# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- SelP_N PF04592.14 KFQ90427.1 - 3.6e-40 137.8 19.2 4e-40 137.7 19.2 1.0 1 0 0 1 1 1 1 Selenoprotein P, N terminal region Zip PF02535.22 KFQ90427.1 - 1.9 7.6 5.7 1.9 7.6 5.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter A2M_recep PF07677.14 KFQ90429.1 - 5.3e-11 43.1 0.6 1.1e-10 42.1 0.2 1.7 2 0 0 2 2 2 1 A-macroglobulin receptor binding domain Cytochrom_B_N_2 PF13631.6 KFQ90430.1 - 0.0018 18.3 0.0 0.0019 18.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Oxidored_q3 PF00499.20 KFQ90431.1 - 7.5e-17 61.4 7.1 7.5e-17 61.4 7.1 1.5 2 0 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Lectin_leg-like PF03388.13 KFQ90432.1 - 1.6e-47 161.8 0.0 4.6e-47 160.3 0.0 1.6 1 1 0 1 1 1 1 Legume-like lectin family Kinocilin PF15033.6 KFQ90432.1 - 0.023 14.3 0.2 0.062 13.0 0.0 1.7 2 0 0 2 2 2 0 Kinocilin protein Hydrolase_6 PF13344.6 KFQ90433.1 - 7.3e-09 35.7 0.0 7.3e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF4032 PF13224.6 KFQ90433.1 - 0.013 15.4 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4032) 7tm_4 PF13853.6 KFQ90434.1 - 1e-48 166.5 16.5 1.3e-48 166.2 16.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ90434.1 - 4.7e-31 108.1 17.2 7e-31 107.5 17.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FGF PF00167.18 KFQ90435.1 - 2.7e-05 24.2 0.1 3.8e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Fibroblast growth factor SR-25 PF10500.9 KFQ90435.1 - 0.038 13.6 4.1 0.047 13.3 4.1 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TraW_N PF12477.8 KFQ90435.1 - 0.092 12.7 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal YabP PF07873.11 KFQ90436.1 - 0.017 14.9 0.1 0.024 14.4 0.1 1.2 1 0 0 1 1 1 0 YabP family 7tm_4 PF13853.6 KFQ90440.1 - 9.5e-55 186.3 17.1 1.1e-54 186.1 17.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ90440.1 - 4.7e-29 101.5 18.6 5.7e-29 101.2 18.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Mito_carr PF00153.27 KFQ90441.1 - 4.8e-33 112.9 0.6 4.8e-11 42.4 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein PetL PF05115.14 KFQ90441.1 - 3.5 7.7 5.9 13 5.8 0.0 2.8 3 0 0 3 3 3 0 Cytochrome B6-F complex subunit VI (PetL) Myosin_head PF00063.21 KFQ90443.1 - 6.4e-195 649.3 4.6 7.4e-195 649.1 4.6 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 KFQ90443.1 - 1.2e-14 53.9 1.4 1.2e-14 53.9 1.4 1.9 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 KFQ90443.1 - 0.007 16.6 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF4537 PF15057.6 KFQ90443.1 - 0.021 14.9 0.1 0.59 10.2 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4537) AAA_16 PF13191.6 KFQ90443.1 - 0.074 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KFQ90443.1 - 0.075 12.5 0.0 0.23 10.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 KFQ90443.1 - 0.099 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SSE PF00437.20 KFQ90443.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 KFQ90443.1 - 0.15 11.8 0.0 0.57 10.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain C1q PF00386.21 KFQ90444.1 - 1.2e-11 44.9 0.0 1.3e-11 44.8 0.0 1.0 1 0 0 1 1 1 1 C1q domain TNF PF00229.18 KFQ90444.1 - 0.065 13.2 0.0 0.065 13.2 0.0 1.0 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family FoP_duplication PF13865.6 KFQ90446.1 - 0.0018 18.8 3.8 0.0018 18.8 3.8 2.2 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 GTA_holin_3TM PF11351.8 KFQ90446.1 - 0.21 12.1 0.1 0.38 11.3 0.1 1.4 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release zf-H2C2_2 PF13465.6 KFQ90447.1 - 4.8e-29 99.5 15.9 1.1e-10 41.4 0.4 3.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ90447.1 - 1.4e-15 56.7 16.0 1.2e-06 28.7 0.2 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ90447.1 - 1.3e-11 44.3 15.5 0.00016 22.2 2.4 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ90447.1 - 7.8e-10 38.8 2.7 0.00018 21.7 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFQ90447.1 - 2.2e-07 30.7 10.7 0.0045 17.0 0.3 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 KFQ90447.1 - 1.2e-05 25.1 9.9 0.00021 21.1 3.3 2.3 2 0 0 2 2 2 2 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 KFQ90447.1 - 1.8e-05 24.7 7.0 0.003 17.7 1.6 2.3 1 1 1 2 2 2 2 Zinc ribbon domain GAGA PF09237.11 KFQ90447.1 - 5.1e-05 23.0 14.9 0.0032 17.3 1.1 3.0 1 1 2 3 3 3 2 GAGA factor Zn-C2H2_12 PF18112.1 KFQ90447.1 - 5.9e-05 23.4 4.2 0.47 11.0 0.0 3.3 3 0 0 3 3 3 1 Autophagy receptor zinc finger-C2H2 domain zf-Di19 PF05605.12 KFQ90447.1 - 0.00018 21.7 3.9 0.00018 21.7 3.9 2.2 1 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Prok-RING_1 PF14446.6 KFQ90447.1 - 0.00063 19.6 1.9 1.5 8.8 0.0 3.1 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 zf_UBZ PF18439.1 KFQ90447.1 - 0.00082 18.9 4.9 0.85 9.3 0.2 3.1 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger FYDLN_acid PF09538.10 KFQ90447.1 - 0.0011 19.6 7.5 0.87 10.3 0.2 3.0 1 1 2 3 3 3 1 Protein of unknown function (FYDLN_acid) zinc_ribbon_9 PF14369.6 KFQ90447.1 - 0.0012 19.1 7.0 0.37 11.1 0.2 3.1 3 0 0 3 3 3 1 zinc-ribbon zf-met PF12874.7 KFQ90447.1 - 0.0012 19.1 8.3 0.2 12.1 0.3 2.8 3 0 0 3 3 2 2 Zinc-finger of C2H2 type DUF3268 PF11672.8 KFQ90447.1 - 0.0036 17.6 0.9 0.018 15.4 0.2 1.9 2 0 0 2 2 2 1 zinc-finger-containing domain YacG PF03884.14 KFQ90447.1 - 0.0064 16.2 5.8 3.9 7.3 0.1 3.2 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG zinc_ribbon_5 PF13719.6 KFQ90447.1 - 0.0077 16.0 5.9 2.1 8.2 0.1 3.1 3 0 0 3 3 3 1 zinc-ribbon domain BolA PF01722.18 KFQ90447.1 - 0.0089 16.3 0.2 1.3 9.4 0.0 2.0 1 1 1 2 2 2 1 BolA-like protein DZR PF12773.7 KFQ90447.1 - 0.012 15.7 10.9 0.47 10.5 10.9 2.2 1 1 0 1 1 1 0 Double zinc ribbon FYVE PF01363.21 KFQ90447.1 - 0.013 15.6 8.4 0.36 11.0 8.4 2.6 1 1 0 1 1 1 0 FYVE zinc finger zf-C2H2_11 PF16622.5 KFQ90447.1 - 0.013 15.2 9.0 0.49 10.2 0.7 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-HIT PF04438.16 KFQ90447.1 - 0.014 15.2 9.7 1.7 8.6 0.2 3.2 3 0 0 3 3 3 0 HIT zinc finger zf-LYAR PF08790.11 KFQ90447.1 - 0.018 14.9 1.6 19 5.3 0.1 3.2 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger C1_4 PF07975.12 KFQ90447.1 - 0.021 15.1 4.8 0.2 11.9 0.7 2.3 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C2HC_2 PF13913.6 KFQ90447.1 - 0.021 14.7 10.9 1.3 9.0 0.0 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 KFQ90447.1 - 0.022 14.6 3.5 1.7 8.6 0.0 2.7 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-ribbon_3 PF13248.6 KFQ90447.1 - 0.022 14.1 10.9 1 8.9 0.4 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_2 PF12756.7 KFQ90447.1 - 0.026 14.9 5.3 1.3 9.4 0.4 2.5 1 1 2 3 3 2 0 C2H2 type zinc-finger (2 copies) zf-trcl PF13451.6 KFQ90447.1 - 0.027 14.4 5.0 1.6 8.7 0.3 3.1 3 0 0 3 3 3 0 Probable zinc-ribbon domain TF_Zn_Ribbon PF08271.12 KFQ90447.1 - 0.035 13.6 5.1 6.5 6.4 0.0 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding TerY_C PF15616.6 KFQ90447.1 - 0.039 14.1 0.9 0.039 14.1 0.9 1.7 1 1 1 2 2 2 0 TerY-C metal binding domain CpXC PF14353.6 KFQ90447.1 - 0.047 13.7 7.9 7.3 6.7 0.1 3.0 2 1 1 3 3 3 0 CpXC protein YhfH PF14149.6 KFQ90447.1 - 0.061 13.3 2.1 11 6.1 0.0 2.8 3 0 0 3 3 3 0 YhfH-like protein XPA_N PF01286.18 KFQ90447.1 - 0.061 13.4 1.7 45 4.2 0.0 3.1 3 0 0 3 3 3 0 XPA protein N-terminal Cript PF10235.9 KFQ90447.1 - 0.064 13.8 2.1 0.57 10.8 0.3 2.5 2 1 0 2 2 2 0 Microtubule-associated protein CRIPT zf-MYST PF17772.1 KFQ90447.1 - 0.067 12.8 1.4 2.7 7.6 0.0 2.3 3 0 0 3 3 2 0 MYST family zinc finger domain FdhE PF04216.12 KFQ90447.1 - 0.07 13.0 6.5 0.048 13.5 2.3 2.1 1 1 0 1 1 1 0 Protein involved in formate dehydrogenase formation zinc_ribbon_15 PF17032.5 KFQ90447.1 - 0.076 13.8 3.9 0.35 11.6 0.9 2.0 1 1 1 2 2 2 0 zinc-ribbon family NADH-G_4Fe-4S_3 PF10588.9 KFQ90447.1 - 0.089 12.3 5.6 2.4 7.8 0.3 3.1 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF2256 PF10013.9 KFQ90447.1 - 0.092 12.9 6.4 2.8 8.1 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) HypA PF01155.19 KFQ90447.1 - 0.11 12.5 4.8 1.2 9.1 4.8 2.0 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF3797 PF12677.7 KFQ90447.1 - 0.12 12.3 3.8 13 5.8 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) zinc-ribbons_6 PF07191.12 KFQ90447.1 - 0.13 12.3 5.5 7.7 6.6 5.5 2.4 1 1 0 1 1 1 0 zinc-ribbons zf-HYPF PF07503.12 KFQ90447.1 - 0.14 11.9 11.8 0.46 10.3 3.2 3.0 1 1 1 2 2 2 0 HypF finger zinc_ribbon_4 PF13717.6 KFQ90447.1 - 0.23 11.4 10.1 11 6.1 0.8 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Rad50_zn_hook PF04423.14 KFQ90447.1 - 0.24 11.2 5.4 0.96 9.3 0.0 3.0 3 0 0 3 3 3 0 Rad50 zinc hook motif TRAF6_Z2 PF18048.1 KFQ90447.1 - 0.27 11.4 11.3 6.4 7.0 0.7 3.3 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 zf-Paramyx-P PF13008.7 KFQ90447.1 - 0.28 10.7 9.1 2.2 7.8 0.1 3.0 3 0 0 3 3 3 0 Zinc-binding domain of Paramyxoviridae V protein zf-C2HE PF16278.5 KFQ90447.1 - 0.32 11.5 6.7 17 5.9 0.3 3.0 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-RING_5 PF14634.6 KFQ90447.1 - 0.36 10.8 8.7 7.6 6.6 0.1 3.0 2 1 0 3 3 3 0 zinc-RING finger domain zf-H2C2_5 PF13909.6 KFQ90447.1 - 0.42 10.4 0.1 0.42 10.4 0.1 3.7 3 1 0 3 3 3 0 C2H2-type zinc-finger domain DNA_ligase_ZBD PF03119.16 KFQ90447.1 - 0.48 10.5 10.4 1.1 9.3 0.1 3.2 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain zf-TFIIB PF13453.6 KFQ90447.1 - 0.52 9.7 7.2 6.2 6.2 3.2 2.8 2 1 0 2 2 2 0 Transcription factor zinc-finger DUF2225 PF09986.9 KFQ90447.1 - 0.8 9.4 7.2 3.3 7.4 0.5 2.7 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) Zn_Tnp_IS1595 PF12760.7 KFQ90447.1 - 0.9 9.6 16.2 1.2 9.2 8.6 2.6 1 1 1 2 2 2 0 Transposase zinc-ribbon domain UBZ_FAAP20 PF15750.5 KFQ90447.1 - 1 9.3 8.3 2.6 8.1 0.1 3.0 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger Cys_rich_CPXG PF14255.6 KFQ90447.1 - 1.4 8.8 5.5 21 5.1 0.1 3.0 3 0 0 3 3 3 0 Cysteine-rich CPXCG zf-AN1 PF01428.16 KFQ90447.1 - 1.6 9.0 12.4 1.8 8.8 0.1 3.4 3 1 0 3 3 3 0 AN1-like Zinc finger zf-CHCC PF10276.9 KFQ90447.1 - 1.8 8.7 0.1 1.8 8.7 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger domain zf-ISL3 PF14690.6 KFQ90447.1 - 1.9 9.2 18.3 0.56 10.9 1.0 3.4 2 1 1 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Ribosomal_L37ae PF01780.19 KFQ90447.1 - 1.9 8.6 7.6 13 6.0 0.3 3.0 1 1 2 3 3 3 0 Ribosomal L37ae protein family OrfB_Zn_ribbon PF07282.11 KFQ90447.1 - 2.7 8.0 8.7 4.2 7.4 2.4 2.8 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Rubredoxin PF00301.20 KFQ90447.1 - 2.7 8.1 9.6 26 4.9 0.4 3.1 3 0 0 3 3 3 0 Rubredoxin DUF4796 PF16044.5 KFQ90447.1 - 2.8 7.5 5.6 4.3 6.9 0.1 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4796) zf-tcix PF14952.6 KFQ90447.1 - 3.2 7.4 8.0 18 5.0 0.7 3.1 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding DUF983 PF06170.12 KFQ90447.1 - 3.4 8.1 4.5 21 5.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF983) TFIIS_C PF01096.18 KFQ90447.1 - 3.5 7.6 9.2 43 4.1 4.7 3.0 2 1 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-CCHC_5 PF14787.6 KFQ90447.1 - 4 7.2 11.3 12 5.7 0.6 3.2 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger Ogr_Delta PF04606.12 KFQ90447.1 - 4.6 7.3 13.8 8.5 6.5 5.0 2.9 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger zinc_ribbon_10 PF10058.9 KFQ90447.1 - 6.1 6.7 7.3 27 4.6 2.7 2.7 2 1 1 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-Mss51 PF13824.6 KFQ90447.1 - 6.8 6.9 13.4 3.7 7.7 0.7 2.9 1 1 2 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C3HC4_2 PF13923.6 KFQ90447.1 - 8.5 6.3 10.2 70 3.4 3.4 3.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Keratin PF02422.16 KFQ90449.1 - 4.2e-35 119.3 13.5 4.5e-35 119.2 13.5 1.0 1 0 0 1 1 1 1 Keratin V-set PF07686.17 KFQ90450.1 - 7.8e-13 48.6 0.0 8.3e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFQ90450.1 - 2e-06 28.3 0.2 3.7e-06 27.4 0.2 1.4 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ90450.1 - 0.0015 18.6 0.0 0.0026 17.8 0.0 1.4 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFQ90450.1 - 0.021 15.0 0.1 0.057 13.6 0.1 1.6 1 1 0 1 1 1 0 Immunoglobulin domain Ig_2 PF13895.6 KFQ90450.1 - 0.021 15.2 0.1 0.054 13.8 0.1 1.6 1 1 0 1 1 1 0 Immunoglobulin domain LRR_8 PF13855.6 KFQ90451.1 - 4.7e-87 285.7 84.1 2e-16 59.5 4.2 5.5 1 1 7 8 8 8 8 Leucine rich repeat LRR_5 PF13306.6 KFQ90451.1 - 3.8e-21 75.4 1.2 4.1e-10 39.7 0.0 2.5 1 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFQ90451.1 - 6.6e-20 70.9 38.8 2.7e-06 27.6 5.1 6.6 2 2 7 9 9 9 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFQ90451.1 - 1.6e-13 50.5 8.7 2.7e-06 27.0 2.9 3.8 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 KFQ90451.1 - 3e-11 42.2 34.5 0.16 12.7 0.1 10.4 10 1 0 10 10 10 5 Leucine Rich Repeat LRR_6 PF13516.6 KFQ90451.1 - 0.00015 21.6 32.8 0.91 9.7 0.6 8.7 9 0 0 9 9 9 4 Leucine Rich repeat LRRNT PF01462.18 KFQ90451.1 - 0.011 15.3 2.8 0.04 13.6 1.9 2.3 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain PT PF04886.12 KFQ90453.1 - 0.026 14.1 30.5 1.8e+04 -18.1 30.5 5.8 1 1 0 1 1 1 0 PT repeat 7tm_4 PF13853.6 KFQ90454.1 - 2.1e-49 168.8 11.2 2.5e-49 168.5 11.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ90454.1 - 5.7e-28 98.0 12.6 7.1e-28 97.6 12.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ90454.1 - 1.8e-06 27.5 11.6 2.7e-06 27.0 11.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFQ90454.1 - 0.00062 19.5 12.3 0.00062 19.5 12.3 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Cadherin_2 PF08266.12 KFQ90455.1 - 2.2e-22 78.7 0.0 1.9e-21 75.7 0.0 2.1 2 0 0 2 2 2 1 Cadherin-like Cadherin PF00028.17 KFQ90455.1 - 1.9e-17 63.5 0.0 4.9e-12 46.1 0.0 2.3 2 0 0 2 2 2 2 Cadherin domain 7tm_4 PF13853.6 KFQ90456.1 - 9.5e-21 74.8 1.8 1.1e-20 74.5 1.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ90456.1 - 0.007 15.7 4.9 0.017 14.4 4.8 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) IalB PF06776.12 KFQ90456.1 - 0.17 11.9 0.1 24 5.0 0.0 2.1 1 1 1 2 2 2 0 Invasion associated locus B (IalB) protein ELYS-bb PF16687.5 KFQ90457.1 - 1.2e-69 235.2 0.4 1.7e-69 234.7 0.4 1.2 1 0 0 1 1 1 1 beta-propeller of ELYS nucleoporin ELYS PF13934.6 KFQ90457.1 - 5.2e-56 190.1 0.8 9.3e-56 189.3 0.8 1.4 1 0 0 1 1 1 1 Nuclear pore complex assembly AT_hook PF02178.19 KFQ90458.1 - 2.6 8.2 26.7 0.072 13.0 1.5 4.2 3 0 0 3 3 3 0 AT hook motif RGM_C PF06534.13 KFQ90459.1 - 6.4e-69 230.9 0.0 7.3e-69 230.7 0.0 1.0 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) C-terminus EFG_IV PF03764.18 KFQ90460.1 - 1.7e-31 108.5 0.0 3.9e-31 107.4 0.0 1.6 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KFQ90460.1 - 3.3e-22 78.3 0.0 7.2e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KFQ90460.1 - 1e-10 41.5 0.0 2.1e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KFQ90460.1 - 4.2e-06 27.1 0.1 9.6e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 NAC PF01849.18 KFQ90461.1 - 1.3e-25 89.2 0.3 2e-25 88.5 0.3 1.3 1 0 0 1 1 1 1 NAC domain Myco_19_kDa PF05481.12 KFQ90461.1 - 0.074 13.3 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen 7tm_4 PF13853.6 KFQ90462.1 - 7.3e-52 176.8 16.9 8.2e-52 176.6 16.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ90462.1 - 2.3e-26 92.7 19.0 3.8e-26 92.0 19.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ90462.1 - 4.1e-05 23.1 18.2 8.9e-05 22.0 18.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx FAM219A PF15260.6 KFQ90463.1 - 3.7e-47 159.8 1.5 4e-47 159.7 1.5 1.0 1 0 0 1 1 1 1 Protein family FAM219A SRCR PF00530.18 KFQ90464.1 - 8.7e-67 221.9 23.6 2.4e-33 114.6 6.3 2.0 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFQ90464.1 - 1e-11 45.2 4.7 5.8e-05 23.5 0.4 2.3 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFQ90464.1 - 6e-06 26.7 2.2 0.068 13.7 0.3 2.3 2 0 0 2 2 2 2 Hepsin, SRCR domain DUF3027 PF11228.8 KFQ90464.1 - 0.058 13.4 5.4 2.8 7.9 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3027) TYW3 PF02676.14 KFQ90464.1 - 0.17 11.2 1.8 4.7 6.5 0.2 2.1 2 0 0 2 2 2 0 Methyltransferase TYW3 Myosin_N PF02736.19 KFQ90465.1 - 1.3e-11 44.1 0.1 1.8e-11 43.7 0.1 1.2 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Trypsin PF00089.26 KFQ90466.1 - 5.3e-66 222.6 2.0 5.9e-66 222.4 2.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFQ90466.1 - 1.6e-06 29.1 0.0 2.8e-06 28.3 0.0 1.3 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFQ90466.1 - 0.00025 21.4 0.0 0.00051 20.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) WD40 PF00400.32 KFQ90467.1 - 0.00016 22.4 0.7 0.17 12.8 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ90467.1 - 0.0042 17.3 0.0 3.4 8.0 0.0 2.1 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain GSHPx PF00255.19 KFQ90468.1 - 1e-36 124.8 0.0 1.3e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KFQ90468.1 - 8.3e-07 29.0 0.0 1.3e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFQ90468.1 - 0.15 11.7 0.0 0.26 11.0 0.0 1.4 1 1 0 1 1 1 0 Redoxin Pex26 PF07163.12 KFQ90469.1 - 0.089 12.1 0.1 0.089 12.1 0.1 1.1 1 0 0 1 1 1 0 Pex26 protein Cohesin_HEAT PF12765.7 KFQ90470.1 - 1.5e-13 50.8 0.2 2.3e-13 50.2 0.2 1.3 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 KFQ90470.1 - 7.6e-06 25.8 0.5 0.0025 17.9 0.0 2.3 2 0 0 2 2 2 2 HEAT repeat HEAT_EZ PF13513.6 KFQ90470.1 - 0.00053 20.4 0.2 0.0091 16.5 0.1 2.2 1 1 1 2 2 2 1 HEAT-like repeat Cnd3 PF12719.7 KFQ90470.1 - 0.0013 18.0 0.1 0.055 12.7 0.0 2.0 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain DUF3385 PF11865.8 KFQ90470.1 - 0.079 12.9 0.0 0.081 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) CcmH PF03918.14 KFQ90470.1 - 0.097 12.0 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein CLASP_N PF12348.8 KFQ90470.1 - 0.15 11.6 0.0 0.29 10.6 0.0 1.5 1 1 0 1 1 1 0 CLASP N terminal Gag_p30 PF02093.16 KFQ90471.1 - 1.4e-18 67.1 0.1 1.8e-18 66.9 0.1 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein 7tm_4 PF13853.6 KFQ90472.1 - 3.6e-36 125.3 9.8 4e-36 125.2 9.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ90472.1 - 1.3e-20 73.8 13.0 1.8e-20 73.4 13.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFQ90472.1 - 0.048 13.0 8.9 0.27 10.6 8.9 2.1 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv SBP56 PF05694.11 KFQ90473.1 - 3.4e-146 487.6 0.0 3.8e-146 487.5 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 KFQ90473.1 - 0.0019 17.5 0.0 0.012 14.9 0.0 1.9 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Folate_carrier PF01770.18 KFQ90474.1 - 8.2e-44 150.0 11.5 1e-43 149.7 11.5 1.1 1 0 0 1 1 1 1 Reduced folate carrier 7tm_4 PF13853.6 KFQ90475.1 - 1.8e-12 47.6 1.1 2.1e-12 47.4 1.1 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ90475.1 - 2.5e-09 36.8 0.4 3.3e-09 36.4 0.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Trefoil PF00088.18 KFQ90476.1 - 2.5e-08 33.7 4.8 3.7e-08 33.1 4.8 1.3 1 0 0 1 1 1 1 Trefoil (P-type) domain NtCtMGAM_N PF16863.5 KFQ90476.1 - 4.6e-05 23.6 0.0 6.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Myosin_head PF00063.21 KFQ90477.1 - 1.3e-210 701.1 2.9 1.6e-210 700.9 2.9 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 KFQ90477.1 - 2.3e-13 49.7 2.3 2.3e-13 49.7 2.3 1.8 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 KFQ90477.1 - 0.0095 16.2 0.0 0.023 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF4537 PF15057.6 KFQ90477.1 - 0.065 13.3 0.2 1 9.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) AAA_16 PF13191.6 KFQ90477.1 - 0.09 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KFQ90477.1 - 0.099 12.1 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 KFQ90477.1 - 0.12 11.4 0.0 0.55 9.2 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein VWA PF00092.28 KFQ90479.1 - 6e-41 140.6 0.6 9.6e-41 139.9 0.6 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain FG-GAP PF01839.23 KFQ90479.1 - 1.9e-17 63.1 8.8 1.3e-08 34.8 1.2 3.8 3 0 0 3 3 3 2 FG-GAP repeat VWA_2 PF13519.6 KFQ90479.1 - 5.9e-14 52.6 0.1 1.4e-13 51.4 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Integrin_alpha2 PF08441.12 KFQ90479.1 - 8e-11 41.5 4.4 1.2e-10 40.9 4.4 1.2 1 0 0 1 1 1 1 Integrin alpha FG-GAP_2 PF14312.6 KFQ90479.1 - 2.8e-07 30.7 4.2 0.019 15.2 0.2 5.2 6 0 0 6 6 6 2 FG-GAP repeat VCBS PF13517.6 KFQ90479.1 - 5.1e-07 30.2 4.9 0.005 17.4 0.2 4.1 4 0 0 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella HisK_sensor PF18698.1 KFQ90479.1 - 0.0016 18.8 2.5 2.1 8.7 0.0 3.6 4 0 0 4 4 4 2 Histidine kinase sensor domain Histone PF00125.24 KFQ90480.1 - 8.2e-48 162.1 0.7 9.2e-48 161.9 0.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KFQ90480.1 - 6.6e-05 23.0 0.1 9.4e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KFQ90480.1 - 0.00029 21.1 0.0 0.00042 20.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KFQ90480.1 - 0.0092 16.2 0.1 0.014 15.7 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFQ90480.1 - 0.1 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit zf-C2H2 PF00096.26 KFQ90481.1 - 9.9e-16 57.2 28.9 1.2e-05 25.5 0.3 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ90481.1 - 2.2e-12 46.8 26.3 0.00024 21.4 0.2 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ90481.1 - 2.9e-11 43.2 26.3 0.00035 21.1 0.3 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ90481.1 - 0.00074 19.7 11.6 0.025 14.9 0.0 3.3 2 1 1 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFQ90481.1 - 0.0011 19.0 28.2 0.36 10.9 0.3 3.8 3 1 0 3 3 3 3 C2H2-type zinc finger OSTMP1 PF09777.9 KFQ90481.1 - 0.002 17.6 0.9 0.0023 17.4 0.9 1.1 1 0 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor zf-C2H2_2 PF12756.7 KFQ90481.1 - 0.0063 16.8 19.0 0.61 10.5 1.5 3.0 1 1 2 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KFQ90481.1 - 0.0094 15.8 7.5 1.6 8.6 0.1 3.0 2 1 1 3 3 3 2 C2H2 type zinc-finger (1 copy) zf-met PF12874.7 KFQ90481.1 - 0.017 15.5 20.2 0.056 13.8 0.5 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf_ZIC PF18366.1 KFQ90481.1 - 0.046 13.8 0.1 0.046 13.8 0.1 3.1 1 1 2 3 3 3 0 Zic proteins zinc finger domain Zn-C2H2_12 PF18112.1 KFQ90481.1 - 0.065 13.7 0.4 0.065 13.7 0.4 3.8 3 2 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain FYVE PF01363.21 KFQ90481.1 - 0.077 13.1 10.8 0.31 11.2 1.6 2.1 1 1 1 2 2 2 0 FYVE zinc finger DUF2256 PF10013.9 KFQ90481.1 - 0.099 12.8 5.6 2.7 8.2 0.2 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) TRAF6_Z2 PF18048.1 KFQ90481.1 - 0.15 12.1 16.2 6.2 7.0 5.1 3.5 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_11 PF16622.5 KFQ90481.1 - 0.24 11.2 16.1 0.79 9.5 4.1 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type UBZ_FAAP20 PF15750.5 KFQ90481.1 - 0.37 10.8 6.1 3.3 7.7 0.2 3.0 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger zinc_ribbon_15 PF17032.5 KFQ90481.1 - 0.4 11.5 6.3 0.87 10.4 2.5 2.1 1 1 1 2 2 2 0 zinc-ribbon family DUF2072 PF09845.9 KFQ90481.1 - 0.71 10.1 11.9 0.48 10.7 0.7 2.5 3 0 0 3 3 3 0 Zn-ribbon containing protein XPA_N PF01286.18 KFQ90481.1 - 0.74 9.9 4.1 6.8 6.8 0.1 2.7 3 0 0 3 3 3 0 XPA protein N-terminal HalOD2 PF18547.1 KFQ90481.1 - 1.1 9.2 5.6 16 5.5 1.2 2.8 2 1 0 2 2 2 0 Halobacterial output domain 2 zf_PR_Knuckle PF18445.1 KFQ90481.1 - 1.8 8.4 6.5 0.6 10.0 0.3 2.6 3 0 0 3 3 3 0 PR zinc knuckle motif CpXC PF14353.6 KFQ90481.1 - 2.9 7.9 9.2 12 6.0 0.2 3.0 1 1 2 3 3 3 0 CpXC protein Mut7-C PF01927.16 KFQ90481.1 - 3.2 7.8 8.0 21 5.2 3.5 2.6 1 1 1 2 2 2 0 Mut7-C RNAse domain zinc_ribbon_4 PF13717.6 KFQ90481.1 - 5.8 6.9 11.7 60 3.7 4.7 3.2 2 1 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 KFQ90481.1 - 6.9 6.7 12.6 3.5 7.6 0.6 2.9 2 1 1 3 3 3 0 SprT-like zinc ribbon domain zf-TFIIB PF13453.6 KFQ90481.1 - 8.6 5.8 7.5 0.81 9.1 1.3 2.2 2 2 1 3 3 3 0 Transcription factor zinc-finger Myosin_head PF00063.21 KFQ90482.1 - 2.1e-84 284.1 0.2 2.3e-84 283.9 0.2 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 KFQ90482.1 - 0.0023 18.2 0.0 0.0029 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFQ90482.1 - 0.016 15.6 0.0 0.02 15.3 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KFQ90482.1 - 0.02 14.4 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 KFQ90482.1 - 0.02 14.6 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SSE PF00437.20 KFQ90482.1 - 0.038 13.0 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 KFQ90482.1 - 0.073 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain TsaE PF02367.17 KFQ90482.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE V-set PF07686.17 KFQ90483.1 - 5.9e-10 39.3 0.0 6.4e-10 39.2 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFQ90483.1 - 0.083 13.0 0.0 0.09 12.8 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin I-set domain zf-H2C2_2 PF13465.6 KFQ90484.1 - 2.6e-13 49.7 12.8 1.2e-09 38.1 3.2 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ90484.1 - 1.1e-10 41.3 7.2 3.1e-06 27.3 0.2 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ90484.1 - 2.4e-07 31.0 7.7 0.00017 22.2 0.3 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ90484.1 - 4.8e-05 23.5 0.6 0.00058 20.1 0.0 2.2 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding CpXC PF14353.6 KFQ90484.1 - 0.002 18.2 0.4 0.18 11.9 0.1 2.0 2 0 0 2 2 2 1 CpXC protein XPA_N PF01286.18 KFQ90484.1 - 0.0023 18.0 0.6 1.4 9.0 0.1 2.1 2 0 0 2 2 2 2 XPA protein N-terminal Zn-ribbon_8 PF09723.10 KFQ90484.1 - 0.0066 16.5 1.8 0.0097 16.0 1.8 1.3 1 0 0 1 1 1 1 Zinc ribbon domain zf-trcl PF13451.6 KFQ90484.1 - 0.018 14.9 2.7 0.043 13.7 2.7 1.7 1 1 0 1 1 1 0 Probable zinc-ribbon domain zf_UBZ PF18439.1 KFQ90484.1 - 0.041 13.5 1.5 2.6 7.7 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 KFQ90484.1 - 0.064 13.6 0.9 0.22 11.9 0.8 1.7 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_ZHX PF18387.1 KFQ90484.1 - 0.17 11.5 1.6 1.9 8.2 0.1 2.0 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_6 PF13912.6 KFQ90484.1 - 1.1 9.3 9.8 2.9 8.0 1.3 2.8 2 2 0 2 2 2 0 C2H2-type zinc finger Arf PF00025.21 KFQ90485.1 - 5.4e-11 42.2 0.8 6.1e-11 42.1 0.8 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KFQ90485.1 - 0.0048 16.1 0.2 0.0048 16.1 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit 6PF2K PF01591.18 KFQ90485.1 - 0.0083 15.5 0.1 0.009 15.3 0.1 1.0 1 0 0 1 1 1 1 6-phosphofructo-2-kinase SRPRB PF09439.10 KFQ90485.1 - 0.045 13.2 0.1 0.049 13.1 0.1 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit SRP54 PF00448.22 KFQ90485.1 - 0.045 13.4 0.1 0.049 13.3 0.1 1.1 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 KFQ90485.1 - 0.11 12.6 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KFQ90485.1 - 0.17 11.2 0.0 0.17 11.2 0.0 1.0 1 0 0 1 1 1 0 Zeta toxin zf-C2H2 PF00096.26 KFQ90486.1 - 4.1e-13 49.0 6.7 3.5e-08 33.5 0.5 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ90486.1 - 3.8e-12 46.0 5.1 2.5e-07 30.8 0.0 3.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ90486.1 - 9.6e-08 32.2 5.9 0.00045 20.8 0.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf_UBZ PF18439.1 KFQ90486.1 - 0.00014 21.4 0.9 0.31 10.7 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 KFQ90486.1 - 0.0002 21.3 3.8 0.22 11.6 0.4 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ90486.1 - 0.00079 19.7 0.1 0.96 9.8 0.1 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding XPA_N PF01286.18 KFQ90486.1 - 0.0028 17.6 1.1 1.8 8.7 0.1 2.2 2 0 0 2 2 2 2 XPA protein N-terminal zf-LYAR PF08790.11 KFQ90486.1 - 0.0038 17.1 3.2 0.084 12.8 0.2 2.2 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger LIM PF00412.22 KFQ90486.1 - 0.0068 16.6 0.2 0.034 14.4 0.2 1.8 1 1 0 1 1 1 1 LIM domain zf_C2H2_ZHX PF18387.1 KFQ90486.1 - 0.013 15.1 0.9 0.11 12.2 0.0 2.0 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_8 PF15909.5 KFQ90486.1 - 0.016 15.5 0.2 0.018 15.3 0.2 1.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon Zn_ribbon_recom PF13408.6 KFQ90486.1 - 0.021 15.4 1.5 0.33 11.5 0.4 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Zn-ribbon_8 PF09723.10 KFQ90486.1 - 0.021 14.9 1.1 0.14 12.3 1.2 2.0 1 1 1 2 2 2 0 Zinc ribbon domain Prok-RING_1 PF14446.6 KFQ90486.1 - 0.033 14.1 0.1 1 9.3 0.1 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 ADK_lid PF05191.14 KFQ90486.1 - 0.033 14.2 0.3 0.24 11.4 0.3 2.3 1 1 0 1 1 1 0 Adenylate kinase, active site lid zf-trcl PF13451.6 KFQ90486.1 - 0.047 13.6 2.2 0.79 9.7 0.1 2.1 2 0 0 2 2 2 0 Probable zinc-ribbon domain DZR PF12773.7 KFQ90486.1 - 0.057 13.4 0.2 0.14 12.2 0.2 1.7 1 1 0 1 1 1 0 Double zinc ribbon DNA_RNApol_7kD PF03604.13 KFQ90486.1 - 0.086 12.5 1.2 1.9 8.2 0.0 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf_C2H2_13 PF18508.1 KFQ90486.1 - 0.11 12.2 0.7 5.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Zinc finger domain YhfH PF14149.6 KFQ90486.1 - 0.12 12.4 1.6 9.1 6.4 0.0 2.1 2 0 0 2 2 2 0 YhfH-like protein CpXC PF14353.6 KFQ90486.1 - 0.14 12.2 0.1 3.2 7.8 0.0 2.0 1 1 1 2 2 2 0 CpXC protein zf-met PF12874.7 KFQ90486.1 - 0.14 12.5 3.3 1.2 9.7 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type TF_Zn_Ribbon PF08271.12 KFQ90486.1 - 0.51 9.9 2.9 3.5 7.2 2.9 2.0 1 1 0 1 1 1 0 TFIIB zinc-binding Rubredoxin_2 PF18073.1 KFQ90486.1 - 0.84 9.4 5.1 4.5 7.1 0.5 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-AN1 PF01428.16 KFQ90486.1 - 1.1 9.4 4.2 3.2 8.0 0.1 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger Synaptobrevin PF00957.21 KFQ90487.1 - 5.1e-21 74.3 0.3 5.5e-21 74.2 0.3 1.0 1 0 0 1 1 1 1 Synaptobrevin PDEase_I PF00233.19 KFQ90488.1 - 1.4e-06 28.2 0.0 1.6e-06 28.0 0.0 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase VirJ PF06057.11 KFQ90490.1 - 0.072 13.0 0.0 0.075 12.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF4567 PF15131.6 KFQ90492.1 - 1.4e-27 95.5 7.1 1.5e-27 95.4 7.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4567) Thymosin PF01290.20 KFQ90493.1 - 1.7e-15 56.5 8.1 1.8e-15 56.4 8.1 1.0 1 0 0 1 1 1 1 Thymosin beta-4 family Ripply PF14998.6 KFQ90494.1 - 2e-20 73.2 0.0 2.3e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Transcription Regulator LRR_6 PF13516.6 KFQ90495.1 - 0.00014 21.7 0.0 0.0022 17.9 0.0 2.0 2 0 0 2 2 2 1 Leucine Rich repeat Homeodomain PF00046.29 KFQ90496.1 - 5.4e-23 80.6 2.9 6.9e-23 80.3 2.9 1.1 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ90496.1 - 5.6e-05 23.0 0.7 0.0001 22.1 0.2 1.7 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.8 KFQ90496.1 - 0.0021 17.5 0.1 0.0028 17.1 0.1 1.2 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez DUF943 PF06092.12 KFQ90496.1 - 0.1 12.3 0.1 0.14 11.9 0.1 1.3 1 1 0 1 1 1 0 Enterobacterial putative membrane protein (DUF943) 6PF2K PF01591.18 KFQ90497.1 - 3.7e-12 46.0 0.2 4.2e-12 45.9 0.2 1.0 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KFQ90497.1 - 0.0013 18.4 0.1 0.0019 18.0 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Homeodomain PF00046.29 KFQ90498.1 - 2.6e-06 27.2 0.4 3.1e-06 26.9 0.4 1.1 1 0 0 1 1 1 1 Homeodomain Homeodomain PF00046.29 KFQ90499.1 - 4.2e-15 55.3 0.5 5.9e-15 54.9 0.5 1.2 1 0 0 1 1 1 1 Homeodomain ATP-synt_F PF01990.17 KFQ90500.1 - 7.2e-17 61.5 0.0 7.8e-17 61.4 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit MH1 PF03165.16 KFQ90501.1 - 7.8e-09 35.7 1.5 1e-08 35.3 1.5 1.2 1 0 0 1 1 1 1 MH1 domain DUF4512 PF14975.6 KFQ90502.1 - 1.8e-13 51.0 0.7 1.9e-13 51.0 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4512) DUF5381 PF17353.2 KFQ90502.1 - 0.14 11.9 0.1 0.16 11.7 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5381) UDPGT PF00201.18 KFQ90503.1 - 5e-20 71.8 0.0 5.3e-20 71.7 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase zf-C2H2 PF00096.26 KFQ90504.1 - 4.7e-14 52.0 2.0 1.6e-07 31.4 1.0 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ90504.1 - 2.9e-10 40.1 1.3 4.3e-05 24.0 0.4 2.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFQ90504.1 - 5e-09 36.2 2.4 5.9e-06 26.5 0.1 2.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-LYAR PF08790.11 KFQ90504.1 - 1.8e-05 24.5 1.0 0.051 13.5 0.1 2.1 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 KFQ90504.1 - 3.8e-05 23.2 0.8 0.053 13.1 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 KFQ90504.1 - 6e-05 22.7 1.7 0.014 15.1 0.4 2.1 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFQ90504.1 - 0.0008 19.3 3.5 0.38 10.8 0.5 2.4 2 1 0 2 2 2 2 C2H2-type zinc finger CpXC PF14353.6 KFQ90504.1 - 0.00082 19.4 0.2 0.12 12.4 0.2 2.0 1 1 0 1 1 1 1 CpXC protein ADK_lid PF05191.14 KFQ90504.1 - 0.0011 18.9 0.0 0.0023 17.9 0.0 1.6 1 1 0 1 1 1 1 Adenylate kinase, active site lid YhfH PF14149.6 KFQ90504.1 - 0.0014 18.6 0.8 0.67 10.0 0.0 2.1 2 0 0 2 2 2 2 YhfH-like protein Zn-ribbon_8 PF09723.10 KFQ90504.1 - 0.0038 17.3 1.5 0.021 14.9 1.6 1.9 1 1 1 2 2 2 2 Zinc ribbon domain DZR PF12773.7 KFQ90504.1 - 0.0065 16.5 0.8 0.0083 16.1 0.8 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-C2HC_2 PF13913.6 KFQ90504.1 - 0.0079 16.1 2.5 1.4 8.9 0.1 2.3 2 0 0 2 2 2 2 zinc-finger of a C2HC-type Zn_ribbon_SprT PF17283.2 KFQ90504.1 - 0.012 15.5 0.3 0.025 14.5 0.3 1.5 1 1 0 1 1 1 0 SprT-like zinc ribbon domain zf-HYPF PF07503.12 KFQ90504.1 - 0.014 15.2 1.6 0.036 13.8 1.6 1.7 1 1 0 1 1 1 0 HypF finger zf-AN1 PF01428.16 KFQ90504.1 - 0.015 15.5 1.3 0.88 9.8 0.3 2.2 1 1 1 2 2 2 0 AN1-like Zinc finger zf-C2HE PF16278.5 KFQ90504.1 - 0.019 15.4 1.2 0.22 12.0 0.2 2.0 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger TRAF6_Z2 PF18048.1 KFQ90504.1 - 0.019 15.0 3.8 1.3 9.2 0.2 2.2 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 LIM PF00412.22 KFQ90504.1 - 0.022 15.0 0.5 0.16 12.2 0.5 1.9 1 1 0 1 1 1 0 LIM domain Prok-RING_1 PF14446.6 KFQ90504.1 - 0.03 14.2 0.7 2.6 8.0 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C2H2_jaz PF12171.8 KFQ90504.1 - 0.03 14.6 0.8 0.64 10.4 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF3268 PF11672.8 KFQ90504.1 - 0.033 14.5 0.1 0.034 14.5 0.1 1.0 1 0 0 1 1 1 0 zinc-finger-containing domain RNA_POL_M_15KD PF02150.16 KFQ90504.1 - 0.046 13.6 0.7 1.5 8.8 0.0 2.1 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-Di19 PF05605.12 KFQ90504.1 - 0.047 14.0 0.2 0.09 13.1 0.2 1.5 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zinc-ribbons_6 PF07191.12 KFQ90504.1 - 0.05 13.6 0.6 0.069 13.1 0.6 1.2 1 0 0 1 1 1 0 zinc-ribbons zf_C2H2_ZHX PF18387.1 KFQ90504.1 - 0.061 13.0 0.6 1.4 8.6 0.1 2.0 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Nudix_N_2 PF14803.6 KFQ90504.1 - 0.065 13.2 0.8 11 6.1 0.0 2.4 2 1 0 2 2 2 0 Nudix N-terminal FYDLN_acid PF09538.10 KFQ90504.1 - 0.072 13.8 0.2 8.3 7.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) TF_Zn_Ribbon PF08271.12 KFQ90504.1 - 0.085 12.4 0.2 0.21 11.1 0.2 1.6 1 1 0 1 1 1 0 TFIIB zinc-binding IBR PF01485.21 KFQ90504.1 - 0.086 13.1 1.0 0.092 13.0 1.0 1.1 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Zn_ribbon_recom PF13408.6 KFQ90504.1 - 0.097 13.2 0.6 3.8 8.1 0.1 2.0 1 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Cys_rich_CPXG PF14255.6 KFQ90504.1 - 0.097 12.6 0.6 2 8.4 0.0 2.1 2 0 0 2 2 2 0 Cysteine-rich CPXCG HNH PF01844.23 KFQ90504.1 - 0.12 12.6 1.6 3.2 8.0 0.2 2.1 2 0 0 2 2 2 0 HNH endonuclease Terminase_GpA PF05876.12 KFQ90504.1 - 0.12 10.9 0.8 0.13 10.8 0.8 1.0 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zf-ribbon_3 PF13248.6 KFQ90504.1 - 0.14 11.6 2.1 5.8 6.5 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_9 PF14369.6 KFQ90504.1 - 0.14 12.4 3.0 4.3 7.7 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon DUF2256 PF10013.9 KFQ90504.1 - 0.16 12.1 0.5 20 5.4 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-met PF12874.7 KFQ90504.1 - 0.17 12.3 1.5 0.31 11.5 0.1 1.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zinc_ribbon_2 PF13240.6 KFQ90504.1 - 0.21 11.3 4.6 5.1 7.0 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.6 KFQ90504.1 - 0.29 10.9 4.2 2.9 7.7 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 KFQ90504.1 - 0.37 10.8 2.6 14 5.7 0.3 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-trcl PF13451.6 KFQ90504.1 - 0.44 10.5 3.8 2.7 7.9 0.2 2.1 2 0 0 2 2 2 0 Probable zinc-ribbon domain Rubredoxin_2 PF18073.1 KFQ90504.1 - 0.48 10.2 5.3 1.3 8.8 0.6 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain DUF1610 PF07754.11 KFQ90504.1 - 1.7 8.7 7.6 8.3 6.5 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) XPA_N PF01286.18 KFQ90504.1 - 2.9 8.0 4.9 20 5.3 0.4 2.1 2 0 0 2 2 2 0 XPA protein N-terminal EF-hand_1 PF00036.32 KFQ90505.1 - 0.00079 18.8 0.0 0.03 13.9 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFQ90505.1 - 0.011 15.6 0.0 0.037 13.9 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain CD225 PF04505.12 KFQ90506.1 - 7.9e-07 29.1 2.0 1.1e-06 28.7 2.0 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein MIOX PF05153.15 KFQ90507.1 - 5.2e-16 59.0 0.0 5.4e-16 58.9 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol oxygenase Spin-Ssty PF02513.17 KFQ90508.1 - 2.2e-29 100.9 0.2 2.5e-29 100.7 0.2 1.1 1 0 0 1 1 1 1 Spin/Ssty Family Histone PF00125.24 KFQ90510.1 - 1.8e-13 51.0 0.0 2e-13 50.9 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFQ90510.1 - 0.00091 19.5 0.0 0.0011 19.2 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Homeodomain PF00046.29 KFQ90511.1 - 4.8e-16 58.3 1.6 5.2e-16 58.2 1.6 1.0 1 0 0 1 1 1 1 Homeodomain DUF2209 PF09974.9 KFQ90511.1 - 0.003 17.9 0.1 0.0032 17.8 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2209) Ras PF00071.22 KFQ90512.1 - 1.7e-13 50.5 0.0 1.8e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ90512.1 - 3.1e-10 40.3 0.0 3.4e-10 40.2 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ90512.1 - 0.053 13.0 0.0 0.054 12.9 0.0 1.0 1 0 0 1 1 1 0 ADP-ribosylation factor family TniB PF05621.11 KFQ90512.1 - 0.12 11.7 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein HLH PF00010.26 KFQ90513.1 - 1.4e-17 63.4 0.1 2.3e-17 62.7 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Peptidase_M14 PF00246.24 KFQ90515.1 - 3.6e-08 33.6 0.0 3.9e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase Ribosomal_S16 PF00886.19 KFQ90519.1 - 3.8e-21 74.9 0.0 4.7e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 zf-C2H2 PF00096.26 KFQ90520.1 - 5.6e-14 51.7 6.9 6.4e-07 29.5 0.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ90520.1 - 4.2e-11 42.8 9.8 1.8e-07 31.2 0.9 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ90520.1 - 7.7e-11 41.9 7.4 5.6e-05 23.6 0.9 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFQ90520.1 - 2.2e-06 27.3 8.1 0.00065 19.4 0.7 2.1 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFQ90520.1 - 0.00032 20.9 0.8 0.69 10.3 0.1 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFQ90520.1 - 0.0011 18.5 1.7 0.25 10.9 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger DZR PF12773.7 KFQ90520.1 - 0.0011 18.9 1.1 0.0015 18.5 1.1 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-C2H2_6 PF13912.6 KFQ90520.1 - 0.0026 17.7 10.4 0.009 16.0 1.8 3.1 2 1 0 2 2 2 1 C2H2-type zinc finger zf-LYAR PF08790.11 KFQ90520.1 - 0.0029 17.5 0.3 0.66 9.9 0.0 2.3 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger Zn-ribbon_8 PF09723.10 KFQ90520.1 - 0.0034 17.5 2.6 0.0099 16.0 2.7 1.7 1 1 1 2 2 2 2 Zinc ribbon domain DUF2256 PF10013.9 KFQ90520.1 - 0.0034 17.5 1.0 1.1 9.4 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HC_2 PF13913.6 KFQ90520.1 - 0.0038 17.1 5.9 0.044 13.7 0.5 2.5 2 1 0 2 2 2 1 zinc-finger of a C2HC-type BolA PF01722.18 KFQ90520.1 - 0.0043 17.3 0.8 2.3 8.6 0.1 2.1 1 1 1 2 2 2 2 BolA-like protein CpXC PF14353.6 KFQ90520.1 - 0.028 14.5 1.4 1.1 9.3 0.1 2.0 1 1 1 2 2 2 0 CpXC protein LIM PF00412.22 KFQ90520.1 - 0.036 14.3 1.9 0.49 10.7 2.1 2.0 1 1 0 1 1 1 0 LIM domain C1_1 PF00130.22 KFQ90520.1 - 0.042 13.7 4.5 0.14 12.0 0.6 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_3rep PF18868.1 KFQ90520.1 - 0.043 14.5 2.4 1.3 9.7 0.2 2.0 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 KFQ90520.1 - 0.048 14.1 5.4 1.3 9.5 0.9 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PknG_rubred PF16919.5 KFQ90520.1 - 0.05 13.8 1.2 0.062 13.5 1.2 1.2 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain ADK_lid PF05191.14 KFQ90520.1 - 0.058 13.4 0.5 0.39 10.7 0.5 2.0 1 1 1 2 2 2 0 Adenylate kinase, active site lid zinc_ribbon_15 PF17032.5 KFQ90520.1 - 0.059 14.1 0.7 0.066 14.0 0.7 1.1 1 0 0 1 1 1 0 zinc-ribbon family XPA_N PF01286.18 KFQ90520.1 - 0.078 13.0 1.2 9.2 6.4 0.1 2.1 2 0 0 2 2 2 0 XPA protein N-terminal zf-Di19 PF05605.12 KFQ90520.1 - 0.091 13.1 2.6 0.1 12.9 2.6 1.1 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 KFQ90520.1 - 0.17 11.6 14.8 0.63 9.9 1.9 3.4 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf_C2H2_13 PF18508.1 KFQ90520.1 - 0.24 11.0 1.8 12 5.6 0.1 2.2 1 1 1 2 2 2 0 Zinc finger domain FYVE PF01363.21 KFQ90520.1 - 0.24 11.5 5.5 0.36 11.0 5.5 1.4 1 1 0 1 1 1 0 FYVE zinc finger Zn_ribbon_recom PF13408.6 KFQ90520.1 - 0.28 11.7 4.7 7.2 7.2 0.3 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain zf_C2H2_ZHX PF18387.1 KFQ90520.1 - 0.5 10.0 5.7 3.8 7.2 0.7 2.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-BED PF02892.15 KFQ90520.1 - 0.55 10.3 6.5 1.2 9.2 0.8 2.1 1 1 1 2 2 2 0 BED zinc finger DUF983 PF06170.12 KFQ90520.1 - 0.72 10.3 1.8 16 6.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) zf-UBP PF02148.19 KFQ90520.1 - 0.87 10.0 6.2 2.2 8.7 6.3 1.6 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Rubredoxin_2 PF18073.1 KFQ90520.1 - 0.9 9.3 6.5 4.3 7.2 0.6 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-C2HE PF16278.5 KFQ90520.1 - 7.2 7.1 6.7 21 5.6 2.1 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Homeodomain PF00046.29 KFQ90522.1 - 2.7e-19 68.7 5.3 3.2e-19 68.5 5.3 1.1 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ90522.1 - 0.00033 20.5 4.0 0.00044 20.1 4.0 1.4 1 1 0 1 1 1 1 Homeobox KN domain DUF1510 PF07423.11 KFQ90522.1 - 0.0012 19.0 0.1 0.0013 18.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1510) CI-B14_5a PF07347.12 KFQ90522.1 - 0.0098 15.8 0.3 0.011 15.6 0.3 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Homeodomain PF00046.29 KFQ90523.1 - 3.5e-22 78.0 6.7 3.9e-22 77.8 6.7 1.0 1 0 0 1 1 1 1 Homeodomain HTH_23 PF13384.6 KFQ90523.1 - 0.0038 17.0 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain Homeobox_KN PF05920.11 KFQ90523.1 - 0.048 13.6 1.4 0.059 13.3 1.4 1.4 1 1 0 1 1 1 0 Homeobox KN domain CI-B14_5a PF07347.12 KFQ90523.1 - 0.072 13.0 0.0 0.094 12.6 0.0 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Spot_14 PF07084.12 KFQ90524.1 - 1e-11 45.2 0.0 1.1e-11 45.0 0.0 1.0 1 0 0 1 1 1 1 Thyroid hormone-inducible hepatic protein Spot 14 CD225 PF04505.12 KFQ90525.1 - 4.6e-08 33.1 2.0 8.2e-08 32.3 2.0 1.4 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF4190 PF13828.6 KFQ90525.1 - 0.46 10.3 2.6 3 7.7 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) ARID PF01388.21 KFQ90529.1 - 4.2e-07 30.6 0.0 4.5e-07 30.5 0.0 1.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain CENP-T_C PF15511.6 KFQ90530.1 - 1.8e-08 34.5 0.1 2.2e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KFQ90530.1 - 2.5e-05 24.4 0.2 3.5e-05 23.9 0.2 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KFQ90530.1 - 4.6e-05 23.7 0.1 6.1e-05 23.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 KFQ90530.1 - 0.00017 21.9 0.3 0.00019 21.8 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFQ90530.1 - 0.00028 21.1 0.1 0.00046 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFQ90530.1 - 0.0059 16.7 0.0 0.0067 16.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KFQ90530.1 - 0.024 14.6 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KFQ90530.1 - 0.21 11.4 0.1 0.25 11.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) PXT1 PF15214.6 KFQ90531.1 - 0.13 12.6 0.4 0.31 11.4 0.1 1.8 2 0 0 2 2 2 0 Peroxisomal testis-specific protein 1 zf-C4 PF00105.18 KFQ90532.1 - 1.9e-18 66.7 5.8 2.2e-18 66.4 5.8 1.1 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF4528 PF15031.6 KFQ90534.1 - 2.6e-42 143.9 0.1 2.8e-42 143.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4528) RIIa PF02197.17 KFQ90535.1 - 6.3e-15 54.5 2.2 7e-15 54.4 2.2 1.0 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Keratin PF02422.16 KFQ90536.1 - 6.1e-22 77.1 9.8 6.4e-22 77.1 9.8 1.0 1 0 0 1 1 1 1 Keratin Fer4_6 PF12837.7 KFQ90536.1 - 0.21 11.7 4.8 0.91 9.7 0.9 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain DUF3432 PF11914.8 KFQ90536.1 - 0.35 11.1 4.4 0.39 11.0 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) zf-H2C2_2 PF13465.6 KFQ90537.1 - 2.4e-25 87.8 27.2 2.4e-08 34.0 0.5 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ90537.1 - 4e-23 80.5 29.9 2.5e-06 27.6 6.1 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ90537.1 - 9e-17 60.3 27.8 0.00065 20.3 0.5 4.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ90537.1 - 3.6e-08 33.5 18.1 0.0071 16.6 0.1 4.1 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFQ90537.1 - 3.3e-05 23.7 31.4 0.018 15.0 1.2 4.6 4 1 1 5 5 5 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFQ90537.1 - 4.7e-05 23.1 23.5 0.02 14.7 1.8 4.1 4 0 0 4 4 4 3 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KFQ90537.1 - 9.6e-05 22.4 14.6 0.048 13.8 1.7 3.4 1 1 3 4 4 4 4 Zinc ribbon domain zf-met PF12874.7 KFQ90537.1 - 0.00015 22.0 24.5 0.09 13.2 0.9 4.1 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf_UBZ PF18439.1 KFQ90537.1 - 0.00023 20.7 16.0 0.27 10.9 0.4 4.3 4 0 0 4 4 4 2 Ubiquitin-Binding Zinc Finger zf_C2H2_ZHX PF18387.1 KFQ90537.1 - 0.00041 19.9 17.3 0.43 10.2 1.8 4.0 1 1 3 4 4 4 3 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_8 PF15909.5 KFQ90537.1 - 0.0031 17.8 9.2 0.4 11.0 0.5 2.2 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-LYAR PF08790.11 KFQ90537.1 - 0.0034 17.3 12.7 2.6 8.0 0.1 4.2 4 0 0 4 4 4 1 LYAR-type C2HC zinc finger DUF3268 PF11672.8 KFQ90537.1 - 0.034 14.5 8.3 0.17 12.2 0.4 2.2 1 1 0 2 2 2 0 zinc-finger-containing domain YhfH PF14149.6 KFQ90537.1 - 0.095 12.7 17.8 11 6.1 0.0 4.2 4 0 0 4 4 4 0 YhfH-like protein zinc_ribbon_15 PF17032.5 KFQ90537.1 - 0.15 12.9 10.3 3.5 8.5 0.7 2.2 1 1 1 2 2 2 0 zinc-ribbon family ADK_lid PF05191.14 KFQ90537.1 - 0.17 11.9 13.0 26 4.9 5.9 4.0 2 1 2 4 4 4 0 Adenylate kinase, active site lid TFIIS_C PF01096.18 KFQ90537.1 - 0.19 11.6 13.7 14 5.7 1.9 4.2 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) Fer4_4 PF12800.7 KFQ90537.1 - 0.25 11.9 1.4 0.25 11.9 1.4 3.9 4 0 0 4 4 4 0 4Fe-4S binding domain zf-C2H2_3rep PF18868.1 KFQ90537.1 - 0.27 11.9 9.1 7.6 7.2 0.5 3.4 1 1 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats Fer4_10 PF13237.6 KFQ90537.1 - 0.84 9.8 12.6 67 3.7 9.0 3.3 2 1 1 3 3 3 0 4Fe-4S dicluster domain DNA_RNApol_7kD PF03604.13 KFQ90537.1 - 1.1 9.0 19.2 15 5.4 0.1 4.3 2 1 1 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2HE PF16278.5 KFQ90537.1 - 1.3 9.5 18.8 0.76 10.3 2.8 4.0 1 1 3 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger LIM PF00412.22 KFQ90537.1 - 1.7 8.9 15.1 47 4.3 6.5 3.4 1 1 2 3 3 3 0 LIM domain Fer4_9 PF13187.6 KFQ90537.1 - 2.4 8.4 14.0 6 7.1 8.6 3.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain CpXC PF14353.6 KFQ90537.1 - 2.7 8.1 13.3 16 5.6 0.0 3.8 2 1 2 4 4 4 0 CpXC protein DUF2256 PF10013.9 KFQ90537.1 - 4.3 7.5 13.5 20 5.4 0.1 4.1 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn_ribbon_recom PF13408.6 KFQ90537.1 - 6 7.5 19.1 5.8 7.5 0.9 3.7 1 1 2 3 3 3 0 Recombinase zinc beta ribbon domain XPA_N PF01286.18 KFQ90537.1 - 8.3 6.6 17.7 16 5.7 0.4 4.2 4 0 0 4 4 4 0 XPA protein N-terminal Colicin_Pyocin PF01320.18 KFQ90538.1 - 0.056 13.6 0.0 0.066 13.3 0.0 1.1 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein Ras PF00071.22 KFQ90539.1 - 1.1e-10 41.3 0.0 1.2e-10 41.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ90539.1 - 1.7e-09 37.9 0.0 1.9e-09 37.8 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 KFQ90539.1 - 0.0032 17.4 0.0 0.0035 17.3 0.0 1.1 1 0 0 1 1 1 1 NACHT domain TniB PF05621.11 KFQ90539.1 - 0.0079 15.6 0.0 0.0079 15.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial TniB protein AAA_22 PF13401.6 KFQ90539.1 - 0.013 15.8 0.0 0.014 15.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFQ90539.1 - 0.02 14.8 0.0 0.02 14.8 0.0 1.0 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 KFQ90539.1 - 0.026 14.0 0.0 0.026 14.0 0.0 1.0 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KFQ90539.1 - 0.039 13.7 0.0 0.043 13.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFQ90539.1 - 0.04 14.3 0.0 0.04 14.3 0.0 1.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KFQ90539.1 - 0.046 13.5 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 KFQ90539.1 - 0.049 13.4 0.0 0.049 13.4 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 KFQ90539.1 - 0.058 12.7 0.0 0.059 12.6 0.0 1.0 1 0 0 1 1 1 0 Septin SRPRB PF09439.10 KFQ90539.1 - 0.064 12.7 0.0 0.067 12.6 0.0 1.0 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Pox_A32 PF04665.12 KFQ90539.1 - 0.066 12.7 0.0 0.066 12.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_5 PF07728.14 KFQ90539.1 - 0.081 12.9 0.0 0.082 12.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MCM PF00493.23 KFQ90539.1 - 0.18 10.9 0.0 0.18 10.9 0.0 1.0 1 0 0 1 1 1 0 MCM P-loop domain Arf PF00025.21 KFQ90539.1 - 0.18 11.2 0.0 0.18 11.2 0.0 1.0 1 0 0 1 1 1 0 ADP-ribosylation factor family IstB_IS21 PF01695.17 KFQ90539.1 - 0.19 11.4 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein zf-H2C2_2 PF13465.6 KFQ90540.1 - 1e-14 54.2 6.8 3.5e-08 33.5 2.6 2.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ90540.1 - 0.00049 20.7 2.1 0.00049 20.7 2.1 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KFQ90540.1 - 0.00092 19.5 3.3 0.00092 19.5 3.3 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFQ90540.1 - 0.0025 18.0 1.5 0.0045 17.2 1.5 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zinc_ribbon_9 PF14369.6 KFQ90540.1 - 0.012 15.8 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 zinc-ribbon zf-H2C2_5 PF13909.6 KFQ90540.1 - 0.051 13.3 14.8 0.75 9.6 5.8 2.8 2 1 0 2 2 2 0 C2H2-type zinc-finger domain F5_F8_type_C PF00754.25 KFQ90541.1 - 2.1e-16 60.2 0.7 2.3e-16 60.1 0.7 1.0 1 0 0 1 1 1 1 F5/8 type C domain CHB_HEX_C_1 PF13290.6 KFQ90541.1 - 0.1 12.7 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain Acetyltransf_1 PF00583.25 KFQ90542.1 - 2.8e-12 46.9 0.0 3.2e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFQ90542.1 - 1.9e-10 41.0 0.1 2.3e-10 40.7 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFQ90542.1 - 4.7e-07 29.8 0.0 6e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFQ90542.1 - 0.00038 20.5 0.0 0.00047 20.2 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KFQ90542.1 - 0.12 12.3 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 FR47-like protein zf-Tim10_DDP PF02953.15 KFQ90544.1 - 4.8e-17 61.3 0.4 6.6e-17 60.9 0.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Nbl1_Borealin_N PF10444.9 KFQ90545.1 - 0.03 14.0 0.4 0.07 12.8 0.1 1.7 1 1 0 1 1 1 0 Nbl1 / Borealin N terminal PurA PF04845.13 KFQ90546.1 - 3.2e-16 59.3 0.0 3.6e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein HAP2-GCS1 PF10699.9 KFQ90546.1 - 0.17 11.9 0.1 4.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Male gamete fusion factor RHD_DNA_bind PF00554.22 KFQ90547.1 - 1.4e-19 70.7 0.0 1.5e-19 70.6 0.0 1.0 1 0 0 1 1 1 1 Rel homology DNA-binding domain Keratin PF02422.16 KFQ90548.1 - 2.1e-35 120.3 11.2 2.1e-35 120.3 11.2 2.0 1 1 1 2 2 2 1 Keratin DUF3432 PF11914.8 KFQ90548.1 - 0.28 11.5 6.3 0.46 10.8 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Vanabin-2 PF11437.8 KFQ90548.1 - 0.32 11.2 5.1 0.4 10.8 5.1 1.1 1 0 0 1 1 1 0 Vanadium-binding protein 2 SET PF00856.28 KFQ90549.1 - 5.2e-14 53.0 0.0 7e-14 52.6 0.0 1.3 1 1 0 1 1 1 1 SET domain zf-H2C2_2 PF13465.6 KFQ90550.1 - 1.1e-13 50.9 22.0 4.8e-06 26.7 1.8 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ90550.1 - 1.5e-08 34.7 24.5 3.2e-05 24.1 3.0 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ90550.1 - 9.9e-08 32.2 23.2 0.00055 20.5 3.0 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFQ90550.1 - 1.7e-07 31.0 21.6 0.00044 20.2 3.0 3.4 3 1 0 3 3 3 3 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFQ90550.1 - 2.4e-05 24.4 14.3 0.098 12.8 0.9 3.1 3 0 0 3 3 3 3 Zinc ribbon domain zf-C2H2_jaz PF12171.8 KFQ90550.1 - 5.7e-05 23.3 7.5 0.012 15.9 0.2 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding XPA_N PF01286.18 KFQ90550.1 - 7.8e-05 22.6 3.0 1.8 8.7 0.1 3.2 3 0 0 3 3 3 2 XPA protein N-terminal zf-met PF12874.7 KFQ90550.1 - 0.00016 21.9 1.2 0.00016 21.9 1.2 2.6 3 0 0 3 3 2 1 Zinc-finger of C2H2 type HalOD2 PF18547.1 KFQ90550.1 - 0.00042 20.2 2.4 0.0058 16.5 0.2 2.2 2 0 0 2 2 2 1 Halobacterial output domain 2 C1_1 PF00130.22 KFQ90550.1 - 0.00071 19.4 8.2 0.0084 16.0 1.8 2.4 1 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_11 PF16622.5 KFQ90550.1 - 0.00085 19.0 13.6 0.55 10.0 0.8 3.2 3 0 0 3 3 3 3 zinc-finger C2H2-type zf_UBZ PF18439.1 KFQ90550.1 - 0.005 16.4 9.1 1.9 8.1 0.4 3.1 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger zf-trcl PF13451.6 KFQ90550.1 - 0.0076 16.1 4.2 8 6.5 0.1 3.1 3 0 0 3 3 3 0 Probable zinc-ribbon domain zf-HIT PF04438.16 KFQ90550.1 - 0.012 15.4 12.0 0.98 9.3 1.3 3.1 3 0 0 3 3 3 0 HIT zinc finger HypA PF01155.19 KFQ90550.1 - 0.014 15.4 4.2 0.064 13.3 4.2 1.8 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Peptidase_C98 PF15499.6 KFQ90550.1 - 0.017 14.6 1.7 0.18 11.2 0.1 2.1 1 1 1 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase zf-H2C2_5 PF13909.6 KFQ90550.1 - 0.017 14.8 13.5 0.94 9.3 0.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-AN1 PF01428.16 KFQ90550.1 - 0.02 15.1 12.3 3 8.1 1.6 3.3 3 1 0 3 3 3 0 AN1-like Zinc finger DZR PF12773.7 KFQ90550.1 - 0.029 14.4 6.2 0.46 10.5 6.2 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-C2HE PF16278.5 KFQ90550.1 - 0.081 13.4 10.5 0.46 11.0 0.6 3.0 1 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger DNA_RNApol_7kD PF03604.13 KFQ90550.1 - 0.11 12.3 9.4 0.73 9.6 0.4 3.2 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Prok-RING_1 PF14446.6 KFQ90550.1 - 0.11 12.4 7.1 5.7 7.0 0.1 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Rubredoxin_2 PF18073.1 KFQ90550.1 - 0.14 11.9 0.8 0.14 11.9 0.8 3.1 3 0 0 3 3 3 0 Rubredoxin metal binding domain zf-Mss51 PF13824.6 KFQ90550.1 - 0.14 12.3 8.5 0.39 10.9 2.4 2.3 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zinc_ribbon_15 PF17032.5 KFQ90550.1 - 0.14 12.9 5.2 2 9.2 5.2 2.0 1 1 0 1 1 1 0 zinc-ribbon family CpXC PF14353.6 KFQ90550.1 - 0.26 11.3 0.1 0.26 11.3 0.1 2.8 1 1 2 3 3 3 0 CpXC protein zf-Paramyx-P PF13008.7 KFQ90550.1 - 0.29 10.6 9.2 0.91 9.0 0.2 3.1 3 0 0 3 3 3 0 Zinc-binding domain of Paramyxoviridae V protein TFIIS_C PF01096.18 KFQ90550.1 - 0.36 10.7 10.7 4.8 7.1 0.3 3.1 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) C1_2 PF03107.16 KFQ90550.1 - 0.6 10.5 14.2 2.4 8.5 4.8 3.0 1 1 0 2 2 2 0 C1 domain Zn_ribbon_SprT PF17283.2 KFQ90550.1 - 0.69 9.9 16.3 0.33 10.9 9.9 2.5 2 1 0 2 2 2 0 SprT-like zinc ribbon domain A2L_zn_ribbon PF08792.10 KFQ90550.1 - 0.84 9.4 8.7 21 5.0 0.3 3.1 3 0 0 3 3 3 0 A2L zinc ribbon domain Cytochrome_C7 PF14522.6 KFQ90550.1 - 0.85 9.7 10.0 25 5.0 10.0 2.6 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Cytochrom_CIII PF02085.16 KFQ90550.1 - 0.97 9.8 8.5 6.6 7.1 8.5 2.0 1 1 0 1 1 1 0 Class III cytochrome C family zf-C2H2_8 PF15909.5 KFQ90550.1 - 1.1 9.6 11.1 0.9 9.9 0.9 2.3 1 1 2 3 3 3 0 C2H2-type zinc ribbon Desulfoferrod_N PF06397.12 KFQ90550.1 - 1.8 8.2 11.7 4.7 6.9 0.4 3.1 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain DUF983 PF06170.12 KFQ90550.1 - 3.8 8.0 5.0 62 4.1 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF983) OrfB_Zn_ribbon PF07282.11 KFQ90550.1 - 4.7 7.2 9.0 6.6 6.7 4.4 2.6 2 1 1 3 3 3 0 Putative transposase DNA-binding domain C1_4 PF07975.12 KFQ90550.1 - 8.5 6.7 12.3 15 5.9 5.5 2.8 1 1 1 2 2 2 0 TFIIH C1-like domain BTB PF00651.31 KFQ90551.1 - 5.5e-24 84.5 0.0 6.3e-24 84.3 0.0 1.0 1 0 0 1 1 1 1 BTB/POZ domain DUF3342 PF11822.8 KFQ90551.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3342) Vg_Tdu PF07545.14 KFQ90554.1 - 7.3e-21 73.6 0.2 3e-20 71.7 0.4 1.8 2 0 0 2 2 2 1 Vestigial/Tondu family TFIIIC_delta PF12657.7 KFQ90555.1 - 0.097 12.6 0.1 0.099 12.6 0.1 1.0 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term Dynein_light PF01221.18 KFQ90556.1 - 2.3e-12 47.1 4.2 2.6e-12 46.9 4.2 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 zf-H2C2_2 PF13465.6 KFQ90560.1 - 9.5e-14 51.1 10.6 8e-06 26.0 0.2 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ90560.1 - 1.5e-13 50.4 20.1 2.5e-06 27.6 1.3 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ90560.1 - 9.1e-09 35.4 18.8 0.0003 21.4 1.9 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KFQ90560.1 - 1.2e-05 25.5 14.2 0.011 16.1 0.4 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFQ90560.1 - 7.7e-05 22.6 12.7 0.27 11.3 0.6 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KFQ90560.1 - 0.00039 20.2 2.6 0.089 12.7 0.1 2.5 1 1 2 3 3 3 2 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 KFQ90560.1 - 0.00085 19.6 1.5 0.00085 19.6 1.5 2.0 1 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KFQ90560.1 - 0.0021 18.3 11.4 0.22 11.8 0.6 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFQ90560.1 - 0.0022 17.7 20.0 0.045 13.5 2.1 3.2 3 0 0 3 3 3 2 C2H2-type zinc-finger domain DZR PF12773.7 KFQ90560.1 - 0.0033 17.4 2.5 0.025 14.6 2.5 1.9 1 1 0 1 1 1 1 Double zinc ribbon Zn_ribbon_SprT PF17283.2 KFQ90560.1 - 0.0034 17.3 9.5 0.0085 16.0 3.5 2.2 2 0 0 2 2 2 1 SprT-like zinc ribbon domain zf-C2H2_2 PF12756.7 KFQ90560.1 - 0.0055 17.0 8.7 0.11 12.8 0.8 2.7 1 1 2 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-CHCC PF10276.9 KFQ90560.1 - 0.0075 16.3 7.0 0.034 14.2 0.2 3.0 3 0 0 3 3 3 1 Zinc-finger domain Zn-C2H2_12 PF18112.1 KFQ90560.1 - 0.022 15.2 8.5 0.67 10.5 0.1 3.0 3 1 0 3 3 2 0 Autophagy receptor zinc finger-C2H2 domain GAGA PF09237.11 KFQ90560.1 - 0.077 12.8 1.4 1.9 8.4 0.2 2.3 1 1 1 2 2 2 0 GAGA factor PyrI_C PF02748.15 KFQ90560.1 - 0.096 12.6 1.1 1.5 8.8 0.1 2.5 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zinc_ribbon_15 PF17032.5 KFQ90560.1 - 0.096 13.4 2.7 0.72 10.6 2.7 1.9 1 1 0 1 1 1 0 zinc-ribbon family zf-C2H2_3rep PF18868.1 KFQ90560.1 - 0.12 13.0 3.3 5.8 7.6 0.0 2.8 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 KFQ90560.1 - 0.13 12.4 6.1 0.47 10.6 0.5 2.8 2 1 1 3 3 3 0 Zinc ribbon domain UBZ_FAAP20 PF15750.5 KFQ90560.1 - 0.16 11.9 0.8 10 6.2 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger zinc_ribbon_4 PF13717.6 KFQ90560.1 - 0.16 11.9 4.9 1.7 8.7 0.3 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_11 PF16622.5 KFQ90560.1 - 0.17 11.7 13.1 0.22 11.3 0.7 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-HIT PF04438.16 KFQ90560.1 - 0.2 11.5 10.4 4.7 7.2 0.4 3.1 3 0 0 3 3 3 0 HIT zinc finger TRAF6_Z2 PF18048.1 KFQ90560.1 - 0.25 11.5 2.9 12 6.0 0.4 2.4 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2HC_2 PF13913.6 KFQ90560.1 - 0.26 11.2 11.6 0.54 10.2 0.7 3.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type DUF2256 PF10013.9 KFQ90560.1 - 0.27 11.4 3.6 6.6 6.9 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_UBZ PF18439.1 KFQ90560.1 - 0.29 10.8 8.0 0.3 10.7 0.2 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-BED PF02892.15 KFQ90560.1 - 0.33 11.0 13.7 0.66 10.1 0.8 3.0 1 1 2 3 3 3 0 BED zinc finger FYVE PF01363.21 KFQ90560.1 - 0.34 11.1 7.0 1 9.6 7.0 1.8 1 1 0 1 1 1 0 FYVE zinc finger PriA_CRR PF18319.1 KFQ90560.1 - 0.39 10.7 13.3 0.32 11.0 0.9 3.2 3 0 0 3 3 3 0 PriA DNA helicase Cys-rich region (CRR) domain HNH_5 PF14279.6 KFQ90560.1 - 0.45 10.4 0.1 0.45 10.4 0.1 2.6 3 0 0 3 3 3 0 HNH endonuclease Zn_ribbon_recom PF13408.6 KFQ90560.1 - 0.78 10.3 9.6 0.72 10.4 3.1 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Zn_Tnp_IS1595 PF12760.7 KFQ90560.1 - 1.4 9.0 8.3 48 4.0 8.3 2.2 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Cript PF10235.9 KFQ90560.1 - 1.4 9.5 5.2 7.8 7.1 0.4 2.5 2 1 0 2 2 2 0 Microtubule-associated protein CRIPT HNH PF01844.23 KFQ90560.1 - 1.6 9.0 9.2 5.8 7.2 0.2 2.9 3 0 0 3 3 3 0 HNH endonuclease MIP PF00230.20 KFQ90561.1 - 5e-32 111.4 1.2 5.8e-32 111.2 1.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF842 PF05811.13 KFQ90562.1 - 5e-24 84.5 9.4 5.5e-24 84.3 9.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) ClpB_D2-small PF10431.9 KFQ90562.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein ELM2 PF01448.24 KFQ90564.1 - 3.1e-07 31.0 0.1 5.2e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-bind_7 PF15963.5 KFQ90564.1 - 0.0028 17.5 0.2 0.0068 16.3 0.1 1.7 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KFQ90564.1 - 0.005 17.0 0.0 0.0087 16.2 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain MH2 PF03166.14 KFQ90565.1 - 1.6e-09 38.2 0.3 1.7e-09 38.2 0.3 1.0 1 0 0 1 1 1 1 MH2 domain UPF0542 PF15086.6 KFQ90566.1 - 2.5e-21 75.4 1.8 2.6e-21 75.3 1.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0542 T_cell_tran_alt PF15128.6 KFQ90566.1 - 0.15 11.9 0.5 0.17 11.7 0.5 1.0 1 0 0 1 1 1 0 T-cell leukemia translocation-altered Lactamase_B PF00753.27 KFQ90568.1 - 4.9e-21 75.6 2.8 2.6e-14 53.7 0.2 2.1 1 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFQ90568.1 - 0.00051 19.6 0.8 0.001 18.6 0.8 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Ribosomal_TL5_C PF14693.6 KFQ90568.1 - 0.041 14.2 0.0 0.072 13.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein TL5, C-terminal domain Histone PF00125.24 KFQ90569.1 - 3e-36 124.7 0.0 3.2e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 KFQ90569.1 - 0.17 12.5 0.1 0.19 12.3 0.1 1.1 1 0 0 1 1 1 0 PCNA-associated factor histone like domain zf-H2C2_2 PF13465.6 KFQ90570.1 - 1e-14 54.2 14.0 5.5e-09 36.0 2.3 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ90570.1 - 4.1e-08 33.2 22.3 1.2e-05 25.5 6.0 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ90570.1 - 1.7e-05 25.3 18.9 0.00049 20.7 4.4 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ90570.1 - 0.00026 21.2 2.1 0.00026 21.2 2.1 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFQ90570.1 - 0.0012 18.7 3.4 0.0012 18.7 3.4 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 KFQ90570.1 - 0.0017 18.6 6.2 0.0017 18.6 6.2 2.0 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KFQ90570.1 - 0.0085 16.5 14.5 0.01 16.2 2.0 3.4 3 1 0 3 3 3 1 Zinc-finger of C2H2 type Elf1 PF05129.13 KFQ90570.1 - 0.013 15.6 3.2 0.017 15.1 3.2 1.3 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-AN1 PF01428.16 KFQ90570.1 - 0.014 15.6 10.2 0.065 13.4 2.8 2.4 1 1 1 2 2 2 0 AN1-like Zinc finger zf-C2H2_9 PF16293.5 KFQ90570.1 - 0.022 14.6 0.4 0.022 14.6 0.4 1.9 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) DUF4428 PF14471.6 KFQ90570.1 - 0.026 14.5 3.8 0.27 11.2 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) Rtf2 PF04641.12 KFQ90570.1 - 0.046 13.1 1.5 0.091 12.1 1.5 1.6 1 1 0 1 1 1 0 Rtf2 RING-finger CpXC PF14353.6 KFQ90570.1 - 0.07 13.2 0.3 0.07 13.2 0.3 1.8 1 1 1 2 2 2 0 CpXC protein Zn-C2H2_12 PF18112.1 KFQ90570.1 - 0.081 13.4 4.5 0.081 13.4 4.5 3.4 3 1 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain DUF2225 PF09986.9 KFQ90570.1 - 0.098 12.4 6.1 0.33 10.7 4.6 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Rad50_zn_hook PF04423.14 KFQ90570.1 - 0.16 11.8 0.1 0.16 11.8 0.1 2.0 3 0 0 3 3 3 0 Rad50 zinc hook motif NADH-G_4Fe-4S_3 PF10588.9 KFQ90570.1 - 0.26 10.9 0.4 0.26 10.9 0.4 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region zf-C2H2_2 PF12756.7 KFQ90570.1 - 0.31 11.4 8.9 0.57 10.5 8.9 1.8 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF2256 PF10013.9 KFQ90570.1 - 0.35 11.0 4.4 1.1 9.4 0.1 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) XPA_N PF01286.18 KFQ90570.1 - 0.65 10.1 6.8 1.6 8.9 0.3 2.8 3 0 0 3 3 3 0 XPA protein N-terminal zf_UBZ PF18439.1 KFQ90570.1 - 0.74 9.5 8.7 0.3 10.7 0.8 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Aldo_ket_red PF00248.21 KFQ90571.1 - 1.7e-12 47.2 0.0 1.8e-12 47.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SMI1_KNR4 PF09346.10 KFQ90571.1 - 0.022 15.1 0.0 0.025 15.0 0.0 1.1 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) zf-C2H2 PF00096.26 KFQ90572.1 - 0.21 12.1 1.3 0.97 10.0 0.5 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type Yae1_N PF09811.9 KFQ90573.1 - 0.0071 16.0 2.7 0.0071 16.0 2.7 3.0 2 1 1 3 3 3 2 Essential protein Yae1, N terminal Oxidored_q3 PF00499.20 KFQ90574.1 - 7.3e-17 61.4 7.1 7.3e-17 61.4 7.1 1.4 2 0 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 IL8 PF00048.20 KFQ90575.1 - 4.1e-07 30.1 0.4 4.9e-07 29.8 0.4 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Sulfotransfer_1 PF00685.27 KFQ90576.1 - 6.6e-55 186.5 0.2 7.3e-55 186.3 0.2 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFQ90576.1 - 0.0025 18.3 0.1 0.0038 17.6 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase family RRM_1 PF00076.22 KFQ90578.1 - 1.4e-33 114.5 0.1 3.1e-17 62.1 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFQ90578.1 - 6.7e-07 28.9 0.1 2e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFQ90578.1 - 3e-06 27.2 0.0 0.0045 17.1 0.0 2.6 2 1 1 3 3 3 2 RNA recognition motif RNA_bind PF08675.11 KFQ90578.1 - 0.00081 19.4 0.0 0.17 11.9 0.0 2.1 2 0 0 2 2 2 2 RNA binding domain RRM_occluded PF16842.5 KFQ90578.1 - 0.011 15.6 0.0 3.4 7.6 0.0 2.4 1 1 1 2 2 2 0 Occluded RNA-recognition motif Calcipressin PF04847.12 KFQ90578.1 - 0.034 13.9 0.0 0.32 10.7 0.0 2.0 1 1 1 2 2 2 0 Calcipressin DbpA PF03880.15 KFQ90578.1 - 0.14 12.2 0.1 2.5 8.2 0.0 2.2 2 0 0 2 2 2 0 DbpA RNA binding domain Nup35_RRM_2 PF14605.6 KFQ90578.1 - 0.14 12.2 0.1 0.55 10.3 0.0 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif HEAT PF02985.22 KFQ90579.1 - 0.019 15.2 0.1 0.062 13.6 0.1 1.9 1 0 0 1 1 1 0 HEAT repeat HSF_DNA-bind PF00447.17 KFQ90580.1 - 1e-17 64.5 0.0 1.1e-17 64.5 0.0 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding 7tm_1 PF00001.21 KFQ90581.1 - 2.3e-07 30.4 11.6 8.1e-07 28.6 11.6 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srbc PF10316.9 KFQ90581.1 - 0.013 15.0 7.9 0.033 13.7 5.8 2.3 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srbc RseC_MucC PF04246.12 KFQ90581.1 - 3.7 7.5 5.4 2 8.4 1.6 2.2 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC LptF_LptG PF03739.14 KFQ90581.1 - 7 5.4 10.5 10 4.8 10.5 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Trypsin PF00089.26 KFQ90582.1 - 1.1e-21 77.7 0.0 1.1e-21 77.6 0.0 1.0 1 0 0 1 1 1 1 Trypsin E1-E2_ATPase PF00122.20 KFQ90583.1 - 4.8e-14 52.3 2.6 5.2e-14 52.2 2.6 1.0 1 0 0 1 1 1 1 E1-E2 ATPase C2 PF00168.30 KFQ90584.1 - 1.2e-21 77.0 0.0 2.3e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain FKBP_C PF00254.28 KFQ90585.1 - 7.5e-05 23.0 0.0 0.00011 22.5 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase BatD PF13584.6 KFQ90585.1 - 0.096 11.5 0.0 0.097 11.5 0.0 1.0 1 0 0 1 1 1 0 Oxygen tolerance Trypsin PF00089.26 KFQ90586.1 - 3.7e-17 62.9 3.0 4e-17 62.8 3.0 1.0 1 0 0 1 1 1 1 Trypsin Histone PF00125.24 KFQ90587.1 - 4e-09 36.9 0.1 4e-09 36.9 0.1 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFQ90587.1 - 1.9e-05 24.9 0.1 3.4e-05 24.0 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MiaE_2 PF13794.6 KFQ90587.1 - 0.031 14.0 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like Sushi PF00084.20 KFQ90588.1 - 4.6e-20 72.0 3.2 2.6e-09 37.6 0.2 2.1 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) LRR_8 PF13855.6 KFQ90589.1 - 5.4e-39 131.8 42.7 1.1e-15 57.2 8.2 9.0 5 3 4 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 KFQ90589.1 - 2.1e-22 78.8 42.9 3.4e-05 24.1 4.9 9.3 6 3 1 8 8 8 6 Leucine Rich repeats (2 copies) TIR PF01582.20 KFQ90589.1 - 3e-21 76.0 0.3 4.7e-21 75.4 0.3 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 KFQ90589.1 - 2.7e-15 57.0 0.1 8.3e-15 55.4 0.1 1.9 2 0 0 2 2 2 1 TIR domain LRR_9 PF14580.6 KFQ90589.1 - 2.4e-07 30.4 11.5 0.00068 19.2 0.0 4.6 2 2 2 5 5 5 3 Leucine-rich repeat LRR_1 PF00560.33 KFQ90589.1 - 2.7e-07 30.2 41.0 0.049 14.2 0.3 12.5 8 2 1 9 9 9 2 Leucine Rich Repeat LRR_5 PF13306.6 KFQ90589.1 - 3.5e-05 23.8 0.0 0.00087 19.3 0.0 3.0 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KFQ90589.1 - 0.0011 18.8 32.4 2.9 8.2 0.2 10.9 11 0 0 11 11 11 2 Leucine Rich repeat DUF1863 PF08937.11 KFQ90589.1 - 0.069 13.5 0.2 0.34 11.2 0.2 2.0 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) HTS PF04204.16 KFQ90589.1 - 0.12 11.2 0.2 1.4 7.8 0.1 2.2 2 0 0 2 2 2 0 Homoserine O-succinyltransferase C2 PF00168.30 KFQ90590.1 - 7.8e-46 154.6 0.0 1.5e-27 95.9 0.0 2.3 2 0 0 2 2 2 2 C2 domain RasGAP PF00616.19 KFQ90590.1 - 8.2e-13 48.5 0.0 1.2e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase zf-CCCH_3 PF15663.5 KFQ90591.1 - 1.5e-11 44.5 0.0 1.7e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Zinc-finger containing family SRF-TF PF00319.18 KFQ90592.1 - 8.9e-07 28.3 0.0 1.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Ig_3 PF13927.6 KFQ90593.1 - 1.9e-88 291.1 7.1 1.9e-13 50.8 0.2 7.3 7 0 0 7 7 7 7 Immunoglobulin domain I-set PF07679.16 KFQ90593.1 - 2.2e-87 287.3 0.0 3.2e-14 52.8 0.0 7.3 7 0 0 7 7 7 7 Immunoglobulin I-set domain Pkinase_Tyr PF07714.17 KFQ90593.1 - 1.9e-82 276.5 0.0 2.6e-82 276.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ig_2 PF13895.6 KFQ90593.1 - 1.5e-66 220.7 7.7 4.7e-11 42.9 0.1 7.3 7 0 0 7 7 7 7 Immunoglobulin domain ig PF00047.25 KFQ90593.1 - 1.2e-47 160.0 1.6 2e-07 31.1 0.0 7.5 7 0 0 7 7 7 7 Immunoglobulin domain Pkinase PF00069.25 KFQ90593.1 - 7.9e-40 136.9 0.0 1.2e-39 136.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain V-set PF07686.17 KFQ90593.1 - 5.4e-27 94.1 11.2 0.016 15.4 0.0 10.2 7 4 2 9 9 9 6 Immunoglobulin V-set domain Ig_6 PF18452.1 KFQ90593.1 - 1.4e-21 75.8 0.2 0.01 15.4 0.0 7.2 7 0 0 7 7 7 6 Immunoglobulin domain Ig_5 PF16681.5 KFQ90593.1 - 8.8e-17 61.3 0.0 0.025 14.9 0.0 7.0 7 1 0 7 7 6 4 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KFQ90593.1 - 3.4e-15 55.9 9.0 0.021 14.9 0.1 7.1 7 0 0 7 7 7 5 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFQ90593.1 - 9.6e-12 45.0 0.4 0.77 10.1 0.0 7.2 7 1 0 7 7 7 3 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 KFQ90593.1 - 2.9e-08 34.0 0.4 0.32 11.4 0.0 5.7 5 0 0 5 5 5 2 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 KFQ90593.1 - 2.8e-07 30.5 0.4 2.4 8.3 0.0 6.2 7 0 0 7 7 6 2 Izumo-like Immunoglobulin domain C2-set PF05790.15 KFQ90593.1 - 1.5e-06 28.3 0.4 1.9 8.7 0.0 6.2 6 0 0 6 6 6 1 Immunoglobulin C2-set domain V-set_CD47 PF08204.11 KFQ90593.1 - 3e-05 24.0 0.1 0.43 10.6 0.0 4.2 4 0 0 4 4 4 2 CD47 immunoglobulin-like domain Adeno_E3_CR1 PF02440.15 KFQ90593.1 - 0.0019 18.0 0.3 7.2 6.5 0.0 5.1 5 1 1 6 6 6 1 Adenovirus E3 region protein CR1 Receptor_2B4 PF11465.8 KFQ90593.1 - 0.074 13.3 0.0 0.98 9.7 0.0 2.9 3 0 0 3 3 3 0 Natural killer cell receptor 2B4 Ig_C17orf99 PF17736.1 KFQ90593.1 - 0.085 12.9 7.1 7.2 6.7 0.0 5.5 6 2 0 6 6 5 0 C17orf99 Ig domain CD34_antigen PF06365.12 KFQ90593.1 - 0.14 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 CD34/Podocalyxin family SOUL PF04832.12 KFQ90594.1 - 1.1e-33 116.8 0.0 1.2e-33 116.7 0.0 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein TPR_12 PF13424.6 KFQ90595.1 - 3.4e-71 235.5 23.5 1.5e-20 73.3 1.2 5.5 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ90595.1 - 1.6e-57 189.9 15.4 1.2e-15 56.8 0.0 7.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ90595.1 - 9.4e-27 91.7 29.2 1.3e-07 31.1 0.5 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ90595.1 - 1.7e-26 90.2 14.2 4e-06 26.5 0.0 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ90595.1 - 1e-18 65.8 25.6 0.00065 19.6 0.4 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ90595.1 - 6.1e-15 54.1 22.5 0.0014 18.7 0.1 6.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KFQ90595.1 - 2.7e-14 53.3 6.3 6.8e-13 48.7 0.4 3.0 3 0 0 3 3 3 1 MalT-like TPR region TPR_16 PF13432.6 KFQ90595.1 - 1.1e-13 51.5 3.2 0.0015 19.1 1.2 5.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ90595.1 - 8.7e-13 48.6 5.9 0.00017 22.1 0.0 4.6 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ90595.1 - 1.5e-09 37.6 11.5 0.068 13.6 0.1 6.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ90595.1 - 3.5e-09 36.7 5.4 5.3 8.1 0.2 6.6 3 1 3 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ90595.1 - 2.9e-07 30.6 11.1 0.0038 17.4 0.1 4.0 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 KFQ90595.1 - 5.9e-07 29.5 1.7 1.8 9.4 0.2 6.6 8 0 0 8 8 6 1 Tetratricopeptide repeat PPR PF01535.20 KFQ90595.1 - 0.00024 21.1 3.4 0.088 13.1 0.0 4.6 6 0 0 6 6 3 1 PPR repeat Uso1_p115_C PF04871.13 KFQ90595.1 - 0.0023 18.3 10.5 0.0023 18.3 10.5 2.5 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region JIP_LZII PF16471.5 KFQ90595.1 - 0.0027 17.8 5.3 0.0027 17.8 5.3 2.6 2 1 0 2 2 2 1 JNK-interacting protein leucine zipper II DUF627 PF04781.12 KFQ90595.1 - 0.0073 16.3 3.9 0.33 11.0 0.1 3.7 2 2 1 3 3 3 1 Protein of unknown function (DUF627) TMF_TATA_bd PF12325.8 KFQ90595.1 - 0.02 15.1 10.4 0.02 15.1 10.4 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding PPR_2 PF13041.6 KFQ90595.1 - 0.02 15.1 0.8 3.3 8.0 0.0 3.4 3 0 0 3 3 3 0 PPR repeat family SHNi-TPR PF10516.9 KFQ90595.1 - 0.03 13.8 2.4 5.2 6.6 0.1 4.1 4 0 0 4 4 4 0 SHNi-TPR Enolase_N PF03952.16 KFQ90595.1 - 0.045 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Enolase, N-terminal domain GHL5 PF14872.6 KFQ90595.1 - 0.056 11.5 2.1 0.082 10.9 2.1 1.2 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 Csm1_N PF18504.1 KFQ90595.1 - 0.12 12.8 8.7 0.61 10.5 8.2 2.6 1 1 0 1 1 1 0 Csm1 N-terminal domain WbqC PF08889.11 KFQ90595.1 - 0.29 11.0 2.6 10 5.9 0.0 3.3 3 1 1 4 4 3 0 WbqC-like protein family COG2 PF06148.11 KFQ90595.1 - 0.36 10.9 8.5 0.23 11.6 5.8 1.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3450 PF11932.8 KFQ90595.1 - 0.54 9.5 9.8 1.2 8.4 9.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 KFQ90595.1 - 0.79 8.5 18.4 1.5 7.6 18.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein RasGAP_C PF03836.15 KFQ90595.1 - 0.86 9.7 11.0 1.2 9.3 9.4 2.1 1 1 0 1 1 1 0 RasGAP C-terminus SOGA PF11365.8 KFQ90595.1 - 1.9 9.7 16.3 17 6.6 10.3 3.8 1 1 0 2 2 2 0 Protein SOGA DUF3972 PF13118.6 KFQ90595.1 - 2.2 8.7 11.4 1.3e+02 3.0 11.4 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3972) FapA PF03961.13 KFQ90595.1 - 2.5 6.6 8.1 4.1 5.9 8.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A YabA PF06156.13 KFQ90595.1 - 3 8.5 16.5 0.096 13.3 4.8 3.6 3 0 0 3 3 3 0 Initiation control protein YabA TPR_11 PF13414.6 KFQ90595.1 - 3.9 7.2 17.8 0.88 9.3 0.2 5.8 6 0 0 6 6 6 0 TPR repeat MIT PF04212.18 KFQ90595.1 - 7.3 6.7 19.6 9.3 6.4 0.8 6.2 5 1 2 7 7 6 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 KFQ90595.1 - 9.5 7.1 16.2 4.2 8.2 0.1 5.9 7 0 0 7 7 5 0 Tetratricopeptide repeat Ribosomal_L2_C PF03947.18 KFQ90596.1 - 7.4e-31 107.0 0.1 1.2e-30 106.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KFQ90596.1 - 9.4e-09 35.1 0.0 2.6e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain G-alpha PF00503.20 KFQ90597.1 - 1.6e-35 122.9 4.5 1.8e-35 122.8 4.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit G-alpha PF00503.20 KFQ90598.1 - 1.1e-114 383.3 3.1 1.3e-114 383.1 3.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFQ90598.1 - 7.1e-14 51.6 0.6 6.2e-13 48.6 0.1 2.6 2 1 1 3 3 3 1 ADP-ribosylation factor family Proteasome PF00227.26 KFQ90599.1 - 1.6e-56 190.8 0.1 1.9e-56 190.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFQ90599.1 - 6.6e-14 51.3 0.0 1.1e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Sortilin-Vps10 PF15902.5 KFQ90600.1 - 3.5e-110 368.9 0.0 5.1e-110 368.3 0.0 1.2 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KFQ90600.1 - 1e-38 133.3 1.9 2.2e-38 132.3 1.9 1.6 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR_6 PF15899.5 KFQ90600.1 - 1.6e-15 55.5 20.5 0.0014 18.5 0.1 7.1 7 0 0 7 7 7 4 BNR-Asp box repeat BNR PF02012.20 KFQ90600.1 - 1.5e-11 42.5 16.9 0.078 13.0 0.5 8.2 8 0 0 8 8 8 4 BNR/Asp-box repeat BNR_2 PF13088.6 KFQ90600.1 - 0.0013 18.1 0.0 0.72 9.1 0.0 3.5 2 2 0 3 3 3 1 BNR repeat-like domain Mo-co_dimer PF03404.16 KFQ90600.1 - 0.0088 16.1 0.0 0.16 12.0 0.0 2.8 3 0 0 3 3 3 1 Mo-co oxidoreductase dimerisation domain CHB_HEX_C PF03174.13 KFQ90600.1 - 0.068 13.2 0.0 2.6 8.1 0.0 3.0 3 0 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain Copine PF07002.16 KFQ90601.1 - 1.8e-61 207.4 0.0 5.2e-61 205.9 0.0 1.7 1 1 0 1 1 1 1 Copine C2 PF00168.30 KFQ90601.1 - 2.2e-24 85.7 0.0 1.1e-13 51.3 0.0 2.3 2 0 0 2 2 2 2 C2 domain VCBS PF13517.6 KFQ90601.1 - 0.046 14.3 0.2 0.15 12.7 0.2 1.9 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella p47_phox_C PF08944.11 KFQ90601.1 - 2.4 7.6 4.5 4.7 6.7 4.5 1.4 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain tRNA-synt_2b PF00587.25 KFQ90603.1 - 1.1e-27 97.2 0.0 1.8e-26 93.2 0.0 2.4 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KFQ90603.1 - 1e-05 25.7 2.6 0.00021 21.5 0.2 2.9 2 1 1 3 3 3 1 Seryl-tRNA synthetase N-terminal domain NOD PF06816.13 KFQ90603.1 - 0.026 14.2 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 NOTCH protein DUF3338 PF11819.8 KFQ90604.1 - 1.2e-28 99.8 0.7 2.8e-28 98.6 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3338) Shisa PF13908.6 KFQ90605.1 - 2.3e-12 47.6 11.6 2.5e-12 47.5 11.6 1.0 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator zf-H2C2_2 PF13465.6 KFQ90606.1 - 4.7e-52 172.2 38.4 1.5e-09 37.8 1.1 7.1 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ90606.1 - 1e-35 120.2 39.1 7.1e-06 26.2 0.8 7.1 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ90606.1 - 1.4e-19 69.1 39.2 0.00031 21.3 0.8 7.1 7 0 0 7 7 7 6 C2H2-type zinc finger zf_UBZ PF18439.1 KFQ90606.1 - 3.6e-09 36.1 12.3 0.22 11.2 0.1 6.2 6 0 0 6 6 6 3 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 KFQ90606.1 - 4.7e-08 33.1 7.3 0.11 12.8 0.4 5.5 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KFQ90606.1 - 4.3e-07 29.9 21.2 0.012 15.8 1.3 4.9 2 2 3 5 5 5 3 Zinc ribbon domain zf-LYAR PF08790.11 KFQ90606.1 - 5.7e-06 26.1 8.8 4.2 7.3 0.1 6.2 6 0 0 6 6 6 1 LYAR-type C2HC zinc finger C1_4 PF07975.12 KFQ90606.1 - 0.0001 22.4 10.9 0.01 16.0 0.1 3.8 2 1 0 3 3 3 1 TFIIH C1-like domain zf-Di19 PF05605.12 KFQ90606.1 - 0.00017 21.8 16.0 0.0021 18.3 2.1 3.9 3 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.16 KFQ90606.1 - 0.00027 21.0 16.3 3.5 7.9 0.1 6.2 6 0 0 6 6 6 1 AN1-like Zinc finger XPA_N PF01286.18 KFQ90606.1 - 0.00034 20.6 12.8 11 6.1 0.5 6.0 6 0 0 6 6 6 0 XPA protein N-terminal zf-trcl PF13451.6 KFQ90606.1 - 0.00038 20.3 14.0 16 5.5 0.0 6.0 6 0 0 6 6 6 0 Probable zinc-ribbon domain zf-met PF12874.7 KFQ90606.1 - 0.00064 20.0 21.9 0.22 12.0 1.2 6.0 6 0 0 6 6 6 1 Zinc-finger of C2H2 type HypA PF01155.19 KFQ90606.1 - 0.0013 18.7 11.1 0.92 9.6 3.5 3.5 1 1 1 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.5 KFQ90606.1 - 0.0034 18.1 11.1 1.2 9.9 2.8 3.4 1 1 2 3 3 3 2 zinc-ribbon family CpXC PF14353.6 KFQ90606.1 - 0.005 16.9 13.7 14 5.8 0.1 5.7 4 2 2 6 6 6 0 CpXC protein zinc_ribbon_4 PF13717.6 KFQ90606.1 - 0.011 15.7 20.4 2.2 8.2 2.4 5.8 5 1 0 5 5 5 0 zinc-ribbon domain FYDLN_acid PF09538.10 KFQ90606.1 - 0.015 16.0 11.8 29 5.4 0.1 5.5 1 1 5 6 6 6 0 Protein of unknown function (FYDLN_acid) DUF2256 PF10013.9 KFQ90606.1 - 0.017 15.2 13.4 24 5.1 0.2 5.9 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF3268 PF11672.8 KFQ90606.1 - 0.023 15.0 8.2 0.7 10.2 0.3 3.3 1 1 2 4 4 4 0 zinc-finger-containing domain DUF4934 PF16288.5 KFQ90606.1 - 0.05 13.5 0.4 7.1 6.6 0.0 3.0 2 1 0 3 3 3 0 Domain of unknown function (DUF4934) TFIIS_C PF01096.18 KFQ90606.1 - 0.054 13.4 19.9 0.35 10.8 1.1 5.3 5 1 0 5 5 5 0 Transcription factor S-II (TFIIS) Zn_ribbon_recom PF13408.6 KFQ90606.1 - 0.11 13.1 21.0 4.1 8.0 1.4 5.2 1 1 3 4 4 4 0 Recombinase zinc beta ribbon domain MBD PF01429.19 KFQ90606.1 - 0.11 12.2 0.4 21 4.9 0.0 3.0 1 1 1 2 2 2 0 Methyl-CpG binding domain YhfH PF14149.6 KFQ90606.1 - 0.11 12.5 17.1 8.5 6.5 0.1 5.5 6 0 0 6 6 6 0 YhfH-like protein DNA_RNApol_7kD PF03604.13 KFQ90606.1 - 0.17 11.6 24.0 7.2 6.4 0.2 6.1 6 0 0 6 6 6 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_11 PF16622.5 KFQ90606.1 - 0.37 10.6 36.5 0.99 9.2 1.3 6.3 7 0 0 7 7 6 0 zinc-finger C2H2-type zinc_ribbon_9 PF14369.6 KFQ90606.1 - 0.49 10.7 17.6 4.7 7.5 0.2 5.3 6 0 0 6 6 6 0 zinc-ribbon LIM PF00412.22 KFQ90606.1 - 0.6 10.4 16.7 5 7.4 1.8 4.5 2 2 2 4 4 4 0 LIM domain zinc-ribbons_6 PF07191.12 KFQ90606.1 - 0.65 10.0 15.6 1.2 9.2 0.8 4.4 1 1 1 3 3 3 0 zinc-ribbons IBR PF01485.21 KFQ90606.1 - 0.89 9.8 17.4 11 6.4 0.7 4.0 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain zf-C2H2_9 PF16293.5 KFQ90606.1 - 0.91 9.4 0.0 0.91 9.4 0.0 3.9 6 0 0 6 6 5 0 C2H2 type zinc-finger (1 copy) BolA PF01722.18 KFQ90606.1 - 1.3 9.3 6.7 20 5.5 0.1 3.6 2 2 2 4 4 4 0 BolA-like protein zf-C2HE PF16278.5 KFQ90606.1 - 1.6 9.3 22.5 1.6 9.2 0.6 5.1 2 2 2 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger zf-ISL3 PF14690.6 KFQ90606.1 - 3 8.6 22.4 1.1 10.0 0.4 5.4 6 0 0 6 6 5 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF2072 PF09845.9 KFQ90606.1 - 3.7 7.8 19.1 10 6.4 2.4 4.7 4 2 0 4 4 4 0 Zn-ribbon containing protein zf-BED PF02892.15 KFQ90606.1 - 3.9 7.6 24.2 11 6.2 1.0 5.0 2 2 3 5 5 4 0 BED zinc finger zf-DNA_Pol PF08996.10 KFQ90606.1 - 4.7 6.9 9.6 6.9 6.4 0.4 2.9 1 1 1 3 3 3 0 DNA Polymerase alpha zinc finger zf_C2H2_ZHX PF18387.1 KFQ90606.1 - 4.9 6.9 26.2 2.8 7.6 0.6 5.8 1 1 5 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 KFQ90606.1 - 7.3 7.0 18.1 15 6.0 0.1 5.1 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-B_box PF00643.24 KFQ90607.1 - 1.5e-09 37.8 8.2 1.9e-09 37.5 8.2 1.2 1 0 0 1 1 1 1 B-box zinc finger Cas_Cas1 PF01867.16 KFQ90607.1 - 0.01 15.0 0.0 0.01 15.0 0.0 1.0 1 0 0 1 1 1 0 CRISPR associated protein Cas1 DUF3421 PF11901.8 KFQ90608.1 - 6.6e-17 61.5 0.2 6.1e-15 55.2 0.0 1.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) zf-H2C2_2 PF13465.6 KFQ90609.1 - 3.9e-46 153.5 40.0 5.5e-09 36.0 0.3 7.0 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ90609.1 - 2.1e-42 141.2 36.8 1.2e-07 31.8 2.0 6.1 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ90609.1 - 2.5e-26 90.1 33.6 1.2e-05 25.7 1.2 6.1 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ90609.1 - 6.6e-21 74.1 3.9 0.012 15.8 0.0 6.1 6 0 0 6 6 6 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFQ90609.1 - 8.6e-16 57.5 36.8 0.00061 19.7 0.6 6.2 6 0 0 6 6 6 5 C2H2-type zinc finger zf-met PF12874.7 KFQ90609.1 - 9.7e-15 54.4 23.2 0.0019 18.5 0.4 6.1 6 0 0 6 6 6 4 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 KFQ90609.1 - 1.6e-10 40.9 15.0 0.0027 17.8 1.2 4.6 3 1 1 4 4 4 2 Zinc ribbon domain zf_UBZ PF18439.1 KFQ90609.1 - 9.5e-10 37.9 11.1 0.75 9.4 0.1 6.2 6 0 0 6 6 6 3 Ubiquitin-Binding Zinc Finger C1_4 PF07975.12 KFQ90609.1 - 4.8e-07 29.9 11.2 0.0051 17.0 2.5 3.9 2 2 2 4 4 4 3 TFIIH C1-like domain zf-C2HC_2 PF13913.6 KFQ90609.1 - 8.1e-07 28.8 4.3 6.8e-05 22.7 1.3 6.0 6 0 0 6 6 6 2 zinc-finger of a C2HC-type DZR PF12773.7 KFQ90609.1 - 1.7e-05 24.7 18.5 5.2e+02 0.8 18.5 3.3 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_3rep PF18868.1 KFQ90609.1 - 5.1e-05 24.0 11.4 1.5 9.5 0.1 5.1 1 1 4 5 5 5 1 Zinc finger C2H2-type, 3 repeats zf-LYAR PF08790.11 KFQ90609.1 - 0.00018 21.4 15.8 3.2 7.7 0.1 6.2 6 0 0 6 6 6 1 LYAR-type C2HC zinc finger DNA_RNApol_7kD PF03604.13 KFQ90609.1 - 0.00024 20.7 19.9 4.6 7.0 0.1 6.0 6 0 0 6 6 6 0 DNA directed RNA polymerase, 7 kDa subunit zf-AN1 PF01428.16 KFQ90609.1 - 0.00053 20.1 20.5 2.3 8.5 0.1 6.2 5 1 1 6 6 6 1 AN1-like Zinc finger zf-trcl PF13451.6 KFQ90609.1 - 0.00062 19.6 7.6 45 4.0 0.0 5.8 6 0 0 6 6 6 0 Probable zinc-ribbon domain zinc_ribbon_15 PF17032.5 KFQ90609.1 - 0.00081 20.1 8.5 0.22 12.3 0.4 3.2 1 1 1 3 3 3 1 zinc-ribbon family zf-C2H2_11 PF16622.5 KFQ90609.1 - 0.0017 18.1 2.9 0.0064 16.2 1.1 5.6 6 0 0 6 6 6 2 zinc-finger C2H2-type Zn_ribbon_SprT PF17283.2 KFQ90609.1 - 0.0022 17.8 1.8 0.0022 17.8 1.8 5.1 5 0 0 5 5 5 1 SprT-like zinc ribbon domain Zn_ribbon_recom PF13408.6 KFQ90609.1 - 0.0032 18.0 21.3 3.2 8.3 2.1 5.4 1 1 2 4 4 4 1 Recombinase zinc beta ribbon domain CpXC PF14353.6 KFQ90609.1 - 0.0048 16.9 15.3 8.5 6.5 0.1 5.6 3 2 2 5 5 5 0 CpXC protein zf-Di19 PF05605.12 KFQ90609.1 - 0.0075 16.6 19.3 0.032 14.5 0.2 4.1 2 1 3 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding DUF3268 PF11672.8 KFQ90609.1 - 0.013 15.8 9.5 1 9.7 0.1 3.2 1 1 0 3 3 3 0 zinc-finger-containing domain DUF2256 PF10013.9 KFQ90609.1 - 0.019 15.1 12.1 8.4 6.6 0.0 5.7 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) HypA PF01155.19 KFQ90609.1 - 0.021 14.8 10.8 1.3 9.1 1.9 3.4 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2HE PF16278.5 KFQ90609.1 - 0.026 15.0 24.6 3.3 8.2 0.4 5.8 1 1 4 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger DUF678 PF05077.12 KFQ90609.1 - 0.04 14.0 5.3 9.4 6.5 0.5 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF678) FYDLN_acid PF09538.10 KFQ90609.1 - 0.049 14.3 11.9 3.6 8.3 0.4 5.1 1 1 4 5 5 5 0 Protein of unknown function (FYDLN_acid) YhfH PF14149.6 KFQ90609.1 - 0.071 13.1 16.3 5.6 7.0 0.0 5.8 6 0 0 6 6 6 0 YhfH-like protein Siva PF05458.12 KFQ90609.1 - 0.12 12.1 4.6 0.4 10.3 1.0 2.5 1 1 2 3 3 3 0 Cd27 binding protein (Siva) XPA_N PF01286.18 KFQ90609.1 - 0.12 12.5 12.9 38 4.5 0.1 5.8 6 0 0 6 6 6 0 XPA protein N-terminal Zf_RING PF16744.5 KFQ90609.1 - 0.15 12.2 10.4 6.6 6.9 0.1 5.1 1 1 5 6 6 6 0 KIAA1045 RING finger zf-C2H2_2 PF12756.7 KFQ90609.1 - 0.21 11.9 16.7 23 5.4 0.1 5.4 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) TFIIS_C PF01096.18 KFQ90609.1 - 0.27 11.1 17.0 20 5.1 0.0 5.9 6 0 0 6 6 6 0 Transcription factor S-II (TFIIS) zf-C2H2_9 PF16293.5 KFQ90609.1 - 0.4 10.5 5.9 6.7 6.6 0.1 4.4 5 0 0 5 5 5 0 C2H2 type zinc-finger (1 copy) U71 PF17474.2 KFQ90609.1 - 0.55 10.2 5.8 43 4.2 0.1 4.2 4 0 0 4 4 4 0 Tegument protein UL11 homolog zf_C2H2_ZHX PF18387.1 KFQ90609.1 - 0.58 9.8 24.4 4.5 7.0 0.1 5.9 1 1 5 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain zf_ZIC PF18366.1 KFQ90609.1 - 1.3 9.2 14.3 55 4.0 0.1 5.7 2 1 4 6 6 6 0 Zic proteins zinc finger domain DUF2757 PF10955.8 KFQ90609.1 - 1.4 9.2 11.3 26 5.1 0.1 5.2 5 1 1 6 6 6 0 Protein of unknown function (DUF2757) LIM PF00412.22 KFQ90609.1 - 1.8 8.8 13.8 24 5.2 0.9 4.7 1 1 4 5 5 5 0 LIM domain RIG-I_C-RD PF11648.8 KFQ90609.1 - 2.3 8.5 7.2 74 3.6 0.0 4.6 5 1 1 6 6 5 0 C-terminal domain of RIG-I ADK_lid PF05191.14 KFQ90609.1 - 3.1 7.9 18.3 15 5.7 0.4 5.6 4 1 2 6 6 6 0 Adenylate kinase, active site lid SCAN PF02023.17 KFQ90610.1 - 2.1e-39 133.2 1.5 2.7e-39 132.9 1.5 1.1 1 0 0 1 1 1 1 SCAN domain Homeodomain PF00046.29 KFQ90611.1 - 6.8e-22 77.1 9.9 1.3e-21 76.2 9.9 1.5 1 0 0 1 1 1 1 Homeodomain Terminase_5 PF06056.12 KFQ90611.1 - 0.095 12.6 0.8 0.3 11.0 0.2 2.0 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) GIT_CC PF16559.5 KFQ90613.1 - 2.4e-33 113.8 5.1 4.9e-33 112.8 5.1 1.6 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor ArfGap PF01412.18 KFQ90613.1 - 3.9e-23 81.8 0.0 7.4e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf GIT_SHD PF08518.11 KFQ90613.1 - 1.8e-11 43.4 0.6 4.6e-11 42.1 0.6 1.8 1 0 0 1 1 1 1 Spa2 homology domain (SHD) of GIT Ank_5 PF13857.6 KFQ90613.1 - 6.1e-08 32.8 0.0 2.4e-07 30.9 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFQ90613.1 - 2.9e-07 30.9 0.0 0.00085 19.8 0.0 2.8 2 1 1 3 3 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFQ90613.1 - 5.6e-07 30.1 0.0 1.7e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFQ90613.1 - 0.00039 20.7 0.5 0.0032 17.8 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat T7SS_ESX_EspC PF10824.8 KFQ90613.1 - 0.0071 16.8 0.1 0.016 15.7 0.1 1.5 1 0 0 1 1 1 1 Excreted virulence factor EspC, type VII ESX diderm SlyX PF04102.12 KFQ90613.1 - 0.012 16.3 2.6 0.026 15.1 2.6 1.6 1 0 0 1 1 1 0 SlyX ZapB PF06005.12 KFQ90613.1 - 0.023 15.1 2.0 0.046 14.2 2.0 1.4 1 0 0 1 1 1 0 Cell division protein ZapB Shugoshin_N PF07558.11 KFQ90613.1 - 0.043 13.7 4.0 0.088 12.7 4.0 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region YabA PF06156.13 KFQ90613.1 - 0.058 14.0 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 Initiation control protein YabA Siah-Interact_N PF09032.11 KFQ90613.1 - 0.072 13.4 0.1 0.22 11.8 0.1 1.8 1 0 0 1 1 1 0 Siah interacting protein, N terminal DUF4147 PF13660.6 KFQ90613.1 - 0.077 12.5 0.1 6.6 6.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) DUF3450 PF11932.8 KFQ90613.1 - 0.1 11.9 2.8 0.16 11.2 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Ank_3 PF13606.6 KFQ90613.1 - 0.11 13.2 0.0 3.4 8.5 0.0 3.1 3 0 0 3 3 2 0 Ankyrin repeat WDCP PF15390.6 KFQ90613.1 - 0.28 9.5 0.9 0.37 9.1 0.9 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF3347 PF11827.8 KFQ90613.1 - 0.34 11.1 1.9 0.6 10.3 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) ADIP PF11559.8 KFQ90613.1 - 0.64 10.1 6.2 1.1 9.3 6.2 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 KFQ90613.1 - 0.88 9.6 5.2 1.6 8.8 5.2 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 KFQ90613.1 - 4.1 7.3 8.9 0.92 9.3 2.7 2.2 1 1 1 2 2 2 0 Septum formation initiator Ada3 PF10198.9 KFQ90613.1 - 8.8 6.5 8.8 15 5.7 1.2 2.3 1 1 1 2 2 2 0 Histone acetyltransferases subunit 3 zf-CXXC PF02008.20 KFQ90614.1 - 1.7e-07 31.1 23.5 2.8e-07 30.5 23.5 1.3 1 0 0 1 1 1 1 CXXC zinc finger domain TCO89 PF10452.9 KFQ90614.1 - 0.032 13.2 6.2 0.047 12.7 6.2 1.1 1 0 0 1 1 1 0 TORC1 subunit TCO89 Striatin PF08232.12 KFQ90614.1 - 0.096 13.3 1.4 0.17 12.5 1.4 1.3 1 0 0 1 1 1 0 Striatin family QueC PF06508.13 KFQ90614.1 - 3.4 7.1 11.0 2 7.9 0.8 2.3 1 1 1 2 2 2 0 Queuosine biosynthesis protein QueC Sec7 PF01369.20 KFQ90615.1 - 6.4e-43 146.6 0.4 1.5e-42 145.4 0.1 1.7 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.6 KFQ90615.1 - 8.1e-38 129.4 3.9 8.6e-38 129.4 0.1 2.6 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 KFQ90615.1 - 1e-13 51.7 0.4 2.2e-13 50.6 0.1 1.8 2 0 0 2 2 2 1 PH domain COBRA1 PF06209.13 KFQ90615.1 - 0.0077 15.2 0.7 0.049 12.5 0.0 2.1 2 0 0 2 2 2 1 Cofactor of BRCA1 (COBRA1) PH_11 PF15413.6 KFQ90615.1 - 0.023 15.1 0.2 0.1 13.0 0.2 2.1 1 0 0 1 1 1 0 Pleckstrin homology domain NADPH_Ox PF08414.10 KFQ90615.1 - 0.08 13.3 0.1 0.23 11.8 0.1 1.8 1 0 0 1 1 1 0 Respiratory burst NADPH oxidase Neuregulin PF02158.15 KFQ90616.1 - 3.8e-166 552.9 33.5 4.8e-166 552.6 33.5 1.1 1 0 0 1 1 1 1 Neuregulin intracellular region I-set PF07679.16 KFQ90616.1 - 9.9e-20 70.4 0.0 2.5e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ90616.1 - 1.4e-16 60.9 0.0 1.4e-16 60.9 0.0 2.6 3 0 0 3 3 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFQ90616.1 - 3.6e-14 52.8 1.3 1.3e-13 51.1 0.0 2.6 4 0 0 4 4 4 1 Immunoglobulin domain ig PF00047.25 KFQ90616.1 - 7.7e-14 51.6 0.0 2.7e-13 49.9 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFQ90616.1 - 0.00014 22.0 1.9 0.0097 16.1 0.0 3.1 2 1 0 2 2 2 1 Immunoglobulin V-set domain Ig_6 PF18452.1 KFQ90616.1 - 0.03 13.9 0.1 0.15 11.6 0.0 2.2 3 0 0 3 3 3 0 Immunoglobulin domain EGF_2 PF07974.13 KFQ90616.1 - 0.065 13.6 10.0 0.18 12.2 10.0 1.9 1 0 0 1 1 1 0 EGF-like domain Izumo-Ig PF16706.5 KFQ90616.1 - 0.08 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain EphA2_TM PF14575.6 KFQ90616.1 - 0.14 13.1 0.0 0.44 11.5 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain EGF PF00008.27 KFQ90616.1 - 0.19 12.1 10.5 0.098 13.0 6.9 2.5 2 0 0 2 2 2 0 EGF-like domain TMEM132D_C PF15706.5 KFQ90616.1 - 0.24 11.2 0.7 0.58 10.0 0.7 1.6 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Ig_4 PF16680.5 KFQ90616.1 - 0.27 11.5 6.8 0.12 12.7 0.4 3.4 3 1 0 3 3 2 0 T-cell surface glycoprotein CD3 delta chain Neur_chan_memb PF02932.16 KFQ90616.1 - 2.1 8.4 6.0 0.31 11.0 0.7 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CYSTM PF12734.7 KFQ90617.1 - 2.5 8.5 47.3 1.8e+03 -0.7 47.3 3.8 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance Prefoldin_2 PF01920.20 KFQ90618.1 - 1.6e-19 69.8 13.0 1.8e-19 69.6 13.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Phage_GP20 PF06810.11 KFQ90618.1 - 0.034 13.9 7.6 0.64 9.8 0.8 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 PEP-utilisers_N PF05524.13 KFQ90618.1 - 0.14 12.3 3.2 8 6.7 0.2 2.1 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF5320 PF17253.2 KFQ90618.1 - 0.28 12.3 0.8 0.39 11.8 0.6 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5320) SlyX PF04102.12 KFQ90618.1 - 1.9 9.1 7.0 8.1 7.1 0.6 2.4 2 0 0 2 2 2 0 SlyX XhlA PF10779.9 KFQ90618.1 - 5.7 7.2 9.4 0.95 9.7 2.6 2.2 2 0 0 2 2 2 0 Haemolysin XhlA EGF PF00008.27 KFQ90619.1 - 7.5e-06 26.2 5.0 1.5e-05 25.1 5.0 1.6 1 0 0 1 1 1 1 EGF-like domain CD34_antigen PF06365.12 KFQ90619.1 - 0.086 12.4 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family EGF_2 PF07974.13 KFQ90619.1 - 3.3 8.2 8.3 0.61 10.5 4.6 1.8 2 1 0 2 2 2 0 EGF-like domain hEGF PF12661.7 KFQ90619.1 - 4.1 8.2 8.0 2 9.2 4.2 2.5 2 1 0 2 2 2 0 Human growth factor-like EGF HCO3_cotransp PF00955.21 KFQ90620.1 - 3.7e-217 722.1 0.4 4.5e-217 721.9 0.4 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 KFQ90620.1 - 3e-66 224.0 0.9 5.2e-48 164.2 0.2 3.2 2 1 1 3 3 3 3 Band 3 cytoplasmic domain Ank_2 PF12796.7 KFQ90621.1 - 1.6e-144 470.9 33.5 1.7e-19 70.2 0.4 12.9 3 3 8 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ90621.1 - 5.2e-118 384.0 17.5 4.4e-10 39.9 0.0 16.6 7 4 9 18 18 18 16 Ankyrin repeats (many copies) Ank PF00023.30 KFQ90621.1 - 3.3e-115 372.0 47.0 5.3e-08 33.0 0.0 23.7 23 0 0 23 23 23 23 Ankyrin repeat Ank_3 PF13606.6 KFQ90621.1 - 4.3e-105 330.8 26.9 6.4e-05 23.1 0.0 24.6 24 0 0 24 24 24 22 Ankyrin repeat Ank_5 PF13857.6 KFQ90621.1 - 3.2e-94 307.7 42.1 5.4e-09 36.1 0.0 19.6 8 4 12 20 20 20 19 Ankyrin repeats (many copies) KH_1 PF00013.29 KFQ90621.1 - 1.4e-14 53.7 0.6 3.8e-14 52.3 0.6 1.8 1 0 0 1 1 1 1 KH domain ScdA_N PF04405.14 KFQ90621.1 - 6.3 6.5 5.4 20 5.0 0.2 4.0 4 0 0 4 4 4 0 Domain of Unknown function (DUF542) SRA1 PF07304.11 KFQ90622.1 - 6.9e-59 197.8 0.2 8.7e-59 197.5 0.2 1.0 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) GUN4 PF05419.12 KFQ90622.1 - 0.038 14.1 0.1 0.085 12.9 0.0 1.6 2 0 0 2 2 2 0 GUN4-like PID PF00640.23 KFQ90623.1 - 7.4e-37 126.5 0.0 7.6e-31 107.0 0.0 2.4 2 1 0 2 2 2 2 Phosphotyrosine interaction domain (PTB/PID) WW PF00397.26 KFQ90623.1 - 1.6e-06 28.1 3.2 4.2e-06 26.7 3.2 1.8 1 0 0 1 1 1 1 WW domain PTB PF08416.13 KFQ90623.1 - 0.0001 22.5 0.0 0.00027 21.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotyrosine-binding domain DnaJ_C PF01556.18 KFQ90624.1 - 1.1e-43 148.9 0.0 1.3e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain PDZ PF00595.24 KFQ90625.1 - 7.6e-10 39.0 0.2 1.4e-09 38.2 0.0 1.5 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFQ90625.1 - 0.018 14.8 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 PDZ domain fn3 PF00041.21 KFQ90626.1 - 3.4e-11 43.3 0.4 6.5e-11 42.4 0.4 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Ank_4 PF13637.6 KFQ90626.1 - 0.0019 18.7 0.0 0.004 17.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Pur_ac_phosph_N PF16656.5 KFQ90626.1 - 0.0059 17.1 1.5 0.023 15.3 1.5 2.0 1 1 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Ank_5 PF13857.6 KFQ90626.1 - 0.0094 16.3 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFQ90626.1 - 0.013 16.1 0.0 0.026 15.1 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Big_5 PF13205.6 KFQ90626.1 - 0.025 15.3 0.0 0.057 14.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain Ank_3 PF13606.6 KFQ90626.1 - 0.04 14.4 0.0 5.9 7.8 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat Retrotrans_gag PF03732.17 KFQ90627.1 - 0.031 14.6 1.8 0.062 13.6 1.8 1.6 1 1 0 1 1 1 0 Retrotransposon gag protein Laminin_N PF00055.17 KFQ90628.1 - 2.1e-70 236.9 0.0 2.1e-70 236.9 0.0 4.5 3 2 1 4 4 4 1 Laminin N-terminal (Domain VI) NTR PF01759.21 KFQ90628.1 - 2.6e-29 101.2 1.6 4.8e-29 100.3 1.6 1.5 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Laminin_EGF PF00053.24 KFQ90628.1 - 1.2e-24 86.1 70.8 1.6e-10 40.9 15.0 4.8 5 0 0 5 5 5 3 Laminin EGF domain TLD PF07534.16 KFQ90629.1 - 1.9e-27 96.2 0.0 1.3e-13 51.4 0.0 2.3 2 0 0 2 2 2 2 TLD RabGAP-TBC PF00566.18 KFQ90629.1 - 1.1e-25 90.5 0.0 1.8e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ATP-synt_C PF00137.21 KFQ90630.1 - 6e-36 122.6 31.1 1.2e-22 79.9 14.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Amidohydro_1 PF01979.20 KFQ90631.1 - 1.2e-19 70.9 0.4 1.5e-19 70.5 0.4 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFQ90631.1 - 1e-06 28.5 0.1 4.8e-06 26.3 0.0 2.0 3 0 0 3 3 3 1 Amidohydrolase family DUF4615 PF15393.6 KFQ90632.1 - 3.1e-38 131.5 7.1 3.1e-38 131.5 7.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4615) NopRA1 PF16201.5 KFQ90632.1 - 0.12 11.9 0.7 0.21 11.2 0.7 1.4 1 1 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 PDE4_UCR PF18100.1 KFQ90632.1 - 1.1 9.9 9.7 0.82 10.3 6.2 2.4 1 1 1 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) Zip PF02535.22 KFQ90632.1 - 1.9 7.6 4.1 2.2 7.4 4.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 KFQ90632.1 - 6.1 5.5 7.2 6.2 5.5 7.2 1.2 1 0 0 1 1 1 0 Presenilin PX PF00787.24 KFQ90633.1 - 0.021 14.8 1.0 0.051 13.6 0.2 1.8 1 1 1 2 2 2 0 PX domain SelP_N PF04592.14 KFQ90633.1 - 0.62 9.4 11.3 0.71 9.2 11.3 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RP-C_C PF11800.8 KFQ90633.1 - 7.1 6.7 7.9 0.48 10.5 3.4 1.3 2 0 0 2 2 2 0 Replication protein C C-terminal region LTD PF00932.19 KFQ90634.1 - 1.2e-09 38.5 0.0 1e-07 32.3 0.0 2.6 2 0 0 2 2 2 2 Lamin Tail Domain RRM_1 PF00076.22 KFQ90635.1 - 2.7e-20 71.9 0.0 4.1e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KFQ90635.1 - 0.00039 20.5 0.0 0.00097 19.2 0.0 1.7 1 0 0 1 1 1 1 Limkain b1 SPX PF03105.19 KFQ90635.1 - 0.00084 19.4 28.6 0.00098 19.1 28.6 1.1 1 0 0 1 1 1 1 SPX domain RRM_3 PF08777.11 KFQ90635.1 - 0.0013 18.7 0.0 0.0038 17.3 0.0 1.8 1 1 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.6 KFQ90635.1 - 0.0018 18.2 0.0 0.0029 17.6 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KFQ90635.1 - 0.0032 17.1 0.0 0.0072 15.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFQ90635.1 - 0.0039 17.3 0.0 0.0088 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 KFQ90635.1 - 0.0049 16.7 0.0 0.0088 15.9 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif Macoilin PF09726.9 KFQ90635.1 - 0.0075 14.9 25.2 0.0092 14.6 25.2 1.1 1 0 0 1 1 1 1 Macoilin family LAP1C PF05609.12 KFQ90635.1 - 0.1 11.6 17.1 0.14 11.2 17.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) BUD22 PF09073.10 KFQ90635.1 - 2.6 7.3 35.5 3.5 6.9 35.5 1.1 1 0 0 1 1 1 0 BUD22 Peptidase_S64 PF08192.11 KFQ90635.1 - 3.6 6.0 21.1 4.3 5.7 21.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 PI3K_1B_p101 PF10486.9 KFQ90635.1 - 3.8 5.2 19.7 4.7 4.9 19.7 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Telomere_reg-2 PF10193.9 KFQ90636.1 - 2.2e-34 118.2 0.8 6.8e-34 116.6 0.2 2.1 2 0 0 2 2 2 1 Telomere length regulation protein RIX1 PF08167.12 KFQ90636.1 - 0.001 18.8 0.2 0.56 9.9 0.0 3.2 3 0 0 3 3 3 2 rRNA processing/ribosome biogenesis L_HMGIC_fpl PF10242.9 KFQ90637.1 - 7.1e-05 23.1 2.0 7.1e-05 23.1 2.0 2.4 1 1 1 2 2 2 1 Lipoma HMGIC fusion partner-like protein Clc-like PF07062.12 KFQ90637.1 - 0.0004 19.9 0.1 0.0004 19.9 0.1 2.1 2 1 1 3 3 3 1 Clc-like Claudin_3 PF06653.11 KFQ90637.1 - 0.00075 19.5 4.5 0.21 11.5 0.1 2.4 2 0 0 2 2 2 2 Tight junction protein, Claudin-like Claudin_2 PF13903.6 KFQ90637.1 - 0.0014 18.5 8.8 0.023 14.4 8.8 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF4418 PF14387.6 KFQ90637.1 - 0.0057 16.8 1.2 0.0057 16.8 1.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4418) PulG PF11773.8 KFQ90637.1 - 0.1 12.4 0.1 0.25 11.2 0.1 1.7 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin SUR7 PF06687.12 KFQ90637.1 - 0.11 12.1 3.4 0.31 10.6 3.3 1.8 1 1 0 1 1 1 0 SUR7/PalI family Neurensin PF14927.6 KFQ90637.1 - 1.3 8.7 4.8 0.93 9.2 0.5 2.5 1 1 1 2 2 2 0 Neurensin Myb_DNA-bind_7 PF15963.5 KFQ90638.1 - 0.0051 16.7 0.2 0.011 15.6 0.2 1.5 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KFQ90638.1 - 0.021 15.0 0.1 0.087 13.0 0.1 2.2 1 1 0 1 1 1 0 Myb-like DNA-binding domain JUPITER PF17054.5 KFQ90639.1 - 9e-08 32.0 7.1 3.1e-05 23.6 0.1 3.6 2 1 2 4 4 4 3 Microtubule-Associated protein Jupiter MBDa PF16564.5 KFQ90639.1 - 0.0027 17.8 0.1 0.046 13.9 0.1 2.2 2 0 0 2 2 2 1 p55-binding region of Methyl-CpG-binding domain proteins MBD Jnk-SapK_ap_N PF09744.9 KFQ90640.1 - 5.9e-57 192.3 24.9 5.9e-57 192.3 24.9 3.8 3 1 1 4 4 4 1 JNK_SAPK-associated protein-1 JIP_LZII PF16471.5 KFQ90640.1 - 1.2e-29 102.3 9.5 1.2e-29 102.3 9.5 4.1 3 1 1 4 4 4 1 JNK-interacting protein leucine zipper II Atg14 PF10186.9 KFQ90640.1 - 0.00019 20.6 6.5 0.00019 20.6 6.5 2.4 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1759 PF03564.15 KFQ90640.1 - 0.17 11.8 5.3 0.49 10.3 5.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) DUF1664 PF07889.12 KFQ90640.1 - 0.23 11.5 16.7 1.7 8.7 5.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) XhlA PF10779.9 KFQ90640.1 - 0.49 10.6 11.7 1.8 8.8 1.2 3.0 3 0 0 3 3 3 0 Haemolysin XhlA ERM PF00769.19 KFQ90640.1 - 2.1 8.1 34.6 0.81 9.5 11.8 3.1 2 1 0 2 2 2 0 Ezrin/radixin/moesin family Prominin PF05478.11 KFQ90640.1 - 2.9 5.7 16.4 2.7 5.8 0.9 2.1 2 0 0 2 2 2 0 Prominin MRP-S34 PF16053.5 KFQ90641.1 - 1.4e-45 154.1 0.3 3.8e-45 152.7 0.3 1.6 1 1 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 NAD_binding_2 PF03446.15 KFQ90642.1 - 6.7e-39 133.6 0.0 1.4e-38 132.6 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFQ90642.1 - 7.4e-23 81.1 1.1 1.3e-22 80.3 1.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PWWP PF00855.17 KFQ90642.1 - 5.6e-14 52.3 1.6 1.1e-13 51.4 0.4 2.1 2 0 0 2 2 2 1 PWWP domain F420_oxidored PF03807.17 KFQ90642.1 - 1.1e-07 32.4 0.0 2.6e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KFQ90642.1 - 0.00015 21.2 0.0 0.0014 18.0 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KFQ90642.1 - 0.00026 21.0 0.0 0.00051 20.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KFQ90642.1 - 0.0004 20.0 0.0 0.00073 19.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KFQ90642.1 - 0.0028 17.6 0.0 0.0077 16.1 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KFQ90642.1 - 0.033 14.4 0.0 0.071 13.4 0.0 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 KFQ90642.1 - 0.16 12.0 0.4 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AT_hook PF02178.19 KFQ90642.1 - 4.4 7.5 11.9 0.1 12.6 4.1 2.6 2 0 0 2 2 2 0 AT hook motif Rogdi_lz PF10259.9 KFQ90643.1 - 3.2e-51 174.3 0.6 3.9e-51 174.1 0.6 1.1 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Takusan PF04822.13 KFQ90643.1 - 5.2 7.0 5.3 0.88 9.5 1.1 1.9 2 0 0 2 2 2 0 Takusan 7tm_1 PF00001.21 KFQ90644.1 - 6.1e-55 186.4 15.8 7e-55 186.2 15.8 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFQ90644.1 - 8.1e-15 54.9 13.8 4.9e-13 49.0 13.8 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 KFQ90644.1 - 7.9e-09 35.3 13.0 1.1e-08 34.8 12.9 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFQ90644.1 - 4.8e-08 33.1 3.8 4.8e-08 33.1 3.8 2.1 2 0 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFQ90644.1 - 0.00042 20.0 9.8 0.00042 20.0 9.8 2.3 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx Flavi_capsid PF01003.19 KFQ90644.1 - 0.12 12.2 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Flavivirus capsid protein C Sigma_reg_N PF13800.6 KFQ90644.1 - 0.15 12.4 0.2 0.15 12.4 0.2 3.1 4 1 0 4 4 4 0 Sigma factor regulator N-terminal IL8 PF00048.20 KFQ90646.1 - 7.6e-17 61.2 0.0 8.7e-17 61.0 0.0 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like ERG2_Sigma1R PF04622.12 KFQ90648.1 - 2.1e-50 171.0 1.1 2.5e-50 170.7 1.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein fn3_3 PF14686.6 KFQ90648.1 - 0.034 13.9 0.9 1.8 8.4 0.3 2.3 2 0 0 2 2 2 0 Polysaccharide lyase family 4, domain II ARID PF01388.21 KFQ90649.1 - 2e-21 76.4 0.0 3.8e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Dynactin_p22 PF07426.11 KFQ90650.1 - 3.3e-41 140.9 2.5 3.8e-41 140.7 2.5 1.0 1 0 0 1 1 1 1 Dynactin subunit p22 MA3 PF02847.17 KFQ90650.1 - 0.0015 18.5 0.2 0.0052 16.8 0.1 1.8 1 1 1 2 2 2 1 MA3 domain DUF3945 PF13101.6 KFQ90650.1 - 0.07 12.9 0.1 5.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3945) SRCR PF00530.18 KFQ90652.1 - 6.3e-98 321.8 28.6 2.9e-29 101.5 2.6 4.4 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Lysyl_oxidase PF01186.17 KFQ90652.1 - 3.1e-53 180.5 0.9 6.1e-53 179.5 0.9 1.5 1 0 0 1 1 1 1 Lysyl oxidase SRCR_2 PF15494.6 KFQ90652.1 - 7.4e-20 71.3 17.2 4.5e-05 23.9 0.2 4.7 4 1 0 4 4 4 4 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFQ90652.1 - 9.6e-11 42.2 3.9 0.0037 17.8 0.1 4.6 4 1 0 4 4 4 4 Hepsin, SRCR domain CUE PF02845.16 KFQ90653.1 - 9.1e-10 38.1 0.0 1.7e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 CUE domain BNIP3 PF06553.12 KFQ90654.1 - 2.9e-21 76.0 0.0 4.2e-21 75.5 0.0 1.2 1 1 0 1 1 1 1 BNIP3 DOCK_N PF16172.5 KFQ90655.1 - 2.9e-105 352.3 0.2 4.9e-105 351.5 0.2 1.4 1 0 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 KFQ90655.1 - 3.8e-100 336.0 0.6 3.8e-100 336.0 0.6 2.2 2 1 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 KFQ90655.1 - 1.2e-60 204.7 0.0 4.4e-60 202.8 0.0 2.0 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins SH3_1 PF00018.28 KFQ90655.1 - 4.7e-05 22.9 0.0 0.0001 21.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFQ90655.1 - 0.00017 21.2 0.0 0.00037 20.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFQ90655.1 - 0.0015 18.3 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain NopRA1 PF16201.5 KFQ90655.1 - 0.054 13.1 0.6 0.24 11.0 0.1 2.3 3 0 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 Nop14 PF04147.12 KFQ90655.1 - 0.3 9.2 0.7 0.58 8.3 0.7 1.4 1 0 0 1 1 1 0 Nop14-like family HA2 PF04408.23 KFQ90656.1 - 2.6e-21 75.9 0.1 6e-21 74.8 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFQ90656.1 - 5.1e-09 36.4 0.0 1.2e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 KFQ90656.1 - 3.4e-05 24.2 0.0 7.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFQ90656.1 - 4.5e-05 23.8 0.0 0.00015 22.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFQ90656.1 - 0.0026 17.5 0.0 0.0046 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFQ90656.1 - 0.0048 17.3 0.2 0.04 14.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 KFQ90656.1 - 0.035 13.1 0.5 0.13 11.3 0.0 2.1 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_25 PF13481.6 KFQ90656.1 - 0.08 12.5 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFQ90656.1 - 0.19 11.5 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 KFQ90656.1 - 0.24 11.3 0.0 0.45 10.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Myosin_tail_1 PF01576.19 KFQ90657.1 - 5.2e-28 97.5 43.0 5.9e-28 97.3 43.0 1.0 1 0 0 1 1 1 1 Myosin tail Tropomyosin PF00261.20 KFQ90657.1 - 0.0031 16.9 43.6 3.4 7.0 12.9 3.4 1 1 0 1 1 1 1 Tropomyosin Bacillus_HBL PF05791.11 KFQ90657.1 - 0.0055 16.6 20.7 0.02 14.7 6.9 2.8 1 1 2 3 3 3 2 Bacillus haemolytic enterotoxin (HBL) DUF3958 PF13125.6 KFQ90657.1 - 0.0083 16.3 9.5 0.0083 16.3 9.5 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF3958) ATG16 PF08614.11 KFQ90657.1 - 0.017 15.4 42.3 0.043 14.0 20.1 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Alanine_zipper PF11839.8 KFQ90657.1 - 0.027 14.8 24.0 1.8 9.0 7.3 4.7 3 2 0 4 4 4 0 Alanine-zipper, major outer membrane lipoprotein Lipoprotein_7 PF01540.16 KFQ90657.1 - 0.044 13.1 17.9 0.065 12.5 17.7 1.4 1 1 0 1 1 1 0 Adhesin lipoprotein Tropomyosin_1 PF12718.7 KFQ90657.1 - 0.11 12.7 42.7 0.1 12.7 17.5 2.6 1 1 1 2 2 2 0 Tropomyosin like CALCOCO1 PF07888.11 KFQ90657.1 - 0.16 10.8 36.5 0.2 10.5 36.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like BRE1 PF08647.11 KFQ90657.1 - 0.19 11.8 40.3 0.061 13.4 9.6 3.1 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase MAD PF05557.13 KFQ90657.1 - 0.24 9.7 40.1 0.045 12.1 20.8 1.8 1 1 0 1 1 1 0 Mitotic checkpoint protein Fib_alpha PF08702.10 KFQ90657.1 - 0.3 11.3 26.6 0.022 15.0 12.8 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Uso1_p115_C PF04871.13 KFQ90657.1 - 0.64 10.4 43.7 4.7 7.6 15.3 3.7 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1664 PF07889.12 KFQ90657.1 - 0.71 9.9 25.6 0.35 10.9 4.7 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 KFQ90657.1 - 0.86 9.9 18.1 17 5.7 1.6 4.2 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) ALMT PF11744.8 KFQ90657.1 - 1.1 8.0 18.4 1.5 7.5 18.4 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter PspA_IM30 PF04012.12 KFQ90657.1 - 1.4 8.4 40.9 1.1 8.7 22.2 2.7 1 1 1 2 2 2 0 PspA/IM30 family Laminin_II PF06009.12 KFQ90657.1 - 1.6 8.7 23.7 7.6 6.6 9.5 3.2 1 1 2 3 3 3 0 Laminin Domain II Tn7_Tnp_TnsA_C PF08721.11 KFQ90657.1 - 2.1 9.1 8.2 0.38 11.4 1.3 3.0 2 2 1 3 3 3 0 TnsA endonuclease C terminal DUF745 PF05335.13 KFQ90657.1 - 2.2 7.9 31.5 4.8 6.9 10.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Leu_zip PF15294.6 KFQ90657.1 - 2.2 7.7 35.4 2.5 7.6 7.1 2.8 1 1 2 3 3 3 0 Leucine zipper AAA_13 PF13166.6 KFQ90657.1 - 2.4 6.7 28.4 3.1 6.3 28.4 1.1 1 0 0 1 1 1 0 AAA domain DUF812 PF05667.11 KFQ90657.1 - 3 6.6 39.3 6.6 5.5 39.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) BT1 PF03092.16 KFQ90657.1 - 4.2 5.5 4.0 4.5 5.4 4.0 1.2 1 0 0 1 1 1 0 BT1 family TolA_bind_tri PF16331.5 KFQ90657.1 - 5 7.3 29.6 0.4 10.8 2.1 4.8 2 2 1 3 3 3 0 TolA binding protein trimerisation TPR_MLP1_2 PF07926.12 KFQ90657.1 - 5.5 7.1 43.0 5.2 7.2 20.4 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein GAS PF13851.6 KFQ90657.1 - 5.8 6.2 44.2 5.7 6.2 15.3 2.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.12 KFQ90657.1 - 6.8 7.2 11.9 15 6.1 1.4 3.6 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DASH_Dad4 PF08650.10 KFQ90657.1 - 7.7 6.6 13.4 4.4 7.3 1.1 3.9 3 1 0 4 4 4 0 DASH complex subunit Dad4 WD40 PF00400.32 KFQ90661.1 - 1e-12 48.3 2.8 0.00052 20.8 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ90661.1 - 7.9e-08 32.5 0.0 0.056 13.7 0.0 3.9 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFQ90661.1 - 5.8e-05 22.2 0.5 0.001 18.1 0.1 2.3 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5122 PF17164.4 KFQ90661.1 - 0.15 12.3 0.9 5 7.5 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller Caskin-tail PF16632.5 KFQ90662.1 - 0.58 10.6 4.8 0.37 11.2 2.5 1.8 1 1 1 2 2 2 0 C-terminal region of Caskin Spc7 PF08317.11 KFQ90662.1 - 0.75 8.6 9.0 0.91 8.3 9.0 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Metallophos PF00149.28 KFQ90663.1 - 1.2e-32 114.1 0.0 1.7e-32 113.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KFQ90663.1 - 0.17 11.5 0.0 0.23 11.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain RVT_1 PF00078.27 KFQ90664.1 - 4.7e-33 114.6 0.0 6.1e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 KFQ90664.1 - 8.5e-08 31.9 0.0 1.7e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase thumb domain RVT_1 PF00078.27 KFQ90665.1 - 4.7e-33 114.6 0.0 6.1e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 KFQ90665.1 - 8.5e-08 31.9 0.0 1.7e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase thumb domain Acyltransferase PF01553.21 KFQ90666.1 - 1.1e-23 83.4 0.0 1.4e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Methyltransf_3 PF01596.17 KFQ90667.1 - 3.1e-74 248.7 0.2 3.8e-74 248.4 0.2 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KFQ90667.1 - 5.5e-14 53.1 0.0 8.3e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFQ90667.1 - 3.3e-06 27.0 0.0 4.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFQ90667.1 - 4.2e-06 27.4 0.0 8.5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFQ90667.1 - 0.00013 21.8 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 KFQ90667.1 - 0.00017 21.0 0.0 0.00031 20.2 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 KFQ90667.1 - 0.0025 17.8 0.0 0.022 14.7 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFQ90667.1 - 0.0066 17.1 0.0 0.018 15.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KFQ90667.1 - 0.016 14.5 0.0 0.02 14.2 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Porin_3 PF01459.22 KFQ90668.1 - 1.2e-85 287.2 5.4 1.4e-85 287.0 5.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin PAP2_C PF14360.6 KFQ90669.1 - 1.5e-27 96.0 10.2 1.5e-27 96.0 10.2 3.0 3 1 0 3 3 3 1 PAP2 superfamily C-terminal SAM_1 PF00536.30 KFQ90669.1 - 2.2e-11 44.0 0.0 3.6e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFQ90669.1 - 4.2e-06 26.8 0.0 8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PAP2 PF01569.21 KFQ90669.1 - 0.0016 18.2 11.4 0.0016 18.2 11.4 2.0 1 1 1 2 2 2 1 PAP2 superfamily SAM_PNT PF02198.16 KFQ90669.1 - 0.028 14.4 0.2 0.26 11.3 0.0 2.6 3 0 0 3 3 3 0 Sterile alpha motif (SAM)/Pointed domain PAP2_3 PF14378.6 KFQ90669.1 - 0.098 12.3 17.1 0.023 14.4 13.4 1.8 1 1 1 2 2 2 0 PAP2 superfamily DSPc PF00782.20 KFQ90670.1 - 1.1e-32 112.6 0.0 1.6e-27 95.9 0.0 2.1 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFQ90670.1 - 0.009 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFQ90671.1 - 3.8e-31 107.6 0.0 5.4e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFQ90671.1 - 0.00062 19.4 0.0 0.00085 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KFQ90671.1 - 0.0008 19.7 0.1 0.0018 18.6 0.0 1.5 1 1 0 1 1 1 1 Rit1 DUSP-like domain DSPn PF14671.6 KFQ90671.1 - 0.0014 19.1 0.0 0.002 18.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half PTPlike_phytase PF14566.6 KFQ90671.1 - 0.029 14.5 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF442 PF04273.13 KFQ90671.1 - 0.033 14.3 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative phosphatase (DUF442) Y_phosphatase3 PF13350.6 KFQ90671.1 - 0.055 13.4 0.0 0.066 13.2 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family PfkB PF00294.24 KFQ90672.1 - 1.6e-77 260.8 0.3 1.8e-77 260.6 0.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KFQ90672.1 - 0.049 13.0 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Raf1_N PF18578.1 KFQ90672.1 - 0.073 13.6 0.4 0.29 11.6 0.1 2.0 2 0 0 2 2 2 0 Rubisco accumulation factor 1 alpha helical domain Adap_comp_sub PF00928.21 KFQ90673.1 - 3.7e-63 213.4 0.1 5.2e-63 212.9 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFQ90673.1 - 5.1e-05 23.2 0.8 0.00015 21.7 0.8 1.8 1 1 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KFQ90673.1 - 0.00024 20.6 0.0 0.00034 20.1 0.0 1.1 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Vinculin PF01044.19 KFQ90674.1 - 0 1523.7 42.7 2.1e-292 973.0 18.3 2.0 1 1 1 2 2 2 2 Vinculin family CARD PF00619.21 KFQ90674.1 - 0.11 12.6 1.0 1 9.4 0.1 3.2 3 0 0 3 3 3 0 Caspase recruitment domain Dynactin_p22 PF07426.11 KFQ90674.1 - 0.28 11.0 14.2 1 9.2 0.0 5.1 5 1 0 5 5 5 0 Dynactin subunit p22 SKA2 PF16740.5 KFQ90674.1 - 1.4 8.7 25.5 6 6.7 2.2 6.6 6 0 0 6 6 6 0 Spindle and kinetochore-associated protein 2 Trypsin PF00089.26 KFQ90675.1 - 4.8e-68 229.3 0.9 6.1e-68 228.9 0.9 1.1 1 0 0 1 1 1 1 Trypsin Kringle PF00051.18 KFQ90675.1 - 1e-17 64.2 4.4 2e-17 63.3 4.4 1.5 1 0 0 1 1 1 1 Kringle domain Trypsin_2 PF13365.6 KFQ90675.1 - 8.5e-06 26.7 0.0 1.4e-05 26.0 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain hEGF PF12661.7 KFQ90675.1 - 0.005 17.4 3.8 0.005 17.4 3.8 3.1 2 0 0 2 2 2 1 Human growth factor-like EGF DUF1986 PF09342.11 KFQ90675.1 - 0.0073 16.7 0.0 0.016 15.6 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) EGF PF00008.27 KFQ90675.1 - 0.0087 16.3 6.7 0.0087 16.3 6.7 3.8 4 1 0 4 4 4 1 EGF-like domain EGF_2 PF07974.13 KFQ90675.1 - 0.015 15.6 8.0 0.015 15.6 8.0 3.1 3 0 0 3 3 3 0 EGF-like domain Pkinase PF00069.25 KFQ90676.1 - 1.4e-71 240.9 0.0 2.3e-71 240.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain CaMKII_AD PF08332.10 KFQ90676.1 - 5.7e-60 201.1 0.0 1e-59 200.3 0.0 1.4 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain Pkinase_Tyr PF07714.17 KFQ90676.1 - 5.5e-32 111.1 0.0 1.8e-31 109.4 0.0 1.8 3 0 0 3 3 3 1 Protein tyrosine kinase SnoaL_3 PF13474.6 KFQ90676.1 - 4.1e-11 43.2 0.0 1e-10 41.9 0.0 1.7 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KFQ90676.1 - 5e-10 39.7 0.0 1.1e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Pkinase_fungal PF17667.1 KFQ90676.1 - 0.0066 15.3 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFQ90676.1 - 0.0075 15.6 0.2 0.017 14.5 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SnoaL_2 PF12680.7 KFQ90676.1 - 0.01 16.4 0.0 0.02 15.5 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain APH PF01636.23 KFQ90676.1 - 0.011 15.7 0.1 2.8 7.8 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KFQ90676.1 - 0.14 11.7 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 RIO1 family HSNSD PF12062.8 KFQ90677.1 - 1.7e-254 845.1 0.0 2.4e-254 844.6 0.0 1.2 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.27 KFQ90677.1 - 7.4e-45 153.5 0.0 1.1e-44 152.9 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFQ90677.1 - 7.1e-09 36.4 0.7 0.0046 17.4 0.0 2.5 1 1 1 2 2 2 2 Sulfotransferase family SWIM PF04434.17 KFQ90678.1 - 0.0034 17.0 6.1 0.0076 15.9 6.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger CHCH PF06747.13 KFQ90679.1 - 2.2e-10 40.4 3.7 2.4e-10 40.3 3.7 1.0 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 KFQ90679.1 - 0.0029 17.8 0.8 0.0031 17.7 0.8 1.1 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Sec23_trunk PF04811.15 KFQ90680.1 - 2e-90 302.6 0.1 2.8e-90 302.2 0.1 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KFQ90680.1 - 2.3e-26 91.6 0.0 5.5e-26 90.4 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KFQ90680.1 - 3.8e-19 69.2 0.1 3.4e-18 66.2 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KFQ90680.1 - 2.9e-14 52.8 11.5 7e-14 51.6 11.5 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KFQ90680.1 - 1.9e-11 43.7 0.0 4.7e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Calsarcin PF05556.11 KFQ90681.1 - 8.6e-11 41.9 2.5 0.0037 16.9 0.1 4.1 2 1 1 4 4 4 3 Calcineurin-binding protein (Calsarcin) PDZ PF00595.24 KFQ90681.1 - 5.5e-07 29.8 0.0 1.3e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFQ90681.1 - 6.4e-05 22.7 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Calsarcin PF05556.11 KFQ90682.1 - 1.7e-104 348.9 0.0 2e-104 348.7 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) p47_phox_C PF08944.11 KFQ90682.1 - 0.085 12.3 0.8 0.19 11.2 0.8 1.6 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain Metallophos PF00149.28 KFQ90684.1 - 2.1e-36 126.4 0.0 3.2e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Annexin PF00191.20 KFQ90685.1 - 2.1e-100 328.8 9.5 1.5e-27 95.5 0.5 4.1 4 0 0 4 4 4 4 Annexin MitMem_reg PF13012.6 KFQ90686.1 - 8.7e-24 84.1 0.7 1.1e-23 83.7 0.2 1.4 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KFQ90686.1 - 1.1e-08 35.0 0.5 2e-08 34.2 0.5 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SH3_1 PF00018.28 KFQ90687.1 - 3.9e-39 132.0 0.7 9.4e-12 44.4 0.0 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 KFQ90687.1 - 1e-38 130.9 2.2 1.6e-14 53.5 0.1 3.9 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 KFQ90687.1 - 2.9e-30 103.7 0.3 2.6e-12 46.2 0.0 3.6 4 0 0 4 4 4 3 Variant SH3 domain Sorb PF02208.16 KFQ90687.1 - 2.8e-19 68.7 1.0 7.4e-19 67.3 1.0 1.8 1 0 0 1 1 1 1 Sorbin homologous domain DUF4749 PF15936.5 KFQ90688.1 - 5.7e-23 81.9 6.0 2.1e-22 80.1 4.3 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4749) PDZ PF00595.24 KFQ90688.1 - 8.3e-13 48.5 0.1 2.3e-12 47.1 0.1 1.8 1 0 0 1 1 1 1 PDZ domain LIM PF00412.22 KFQ90688.1 - 1.9e-11 44.0 5.3 3.6e-11 43.1 5.3 1.4 1 0 0 1 1 1 1 LIM domain PDZ_6 PF17820.1 KFQ90688.1 - 8.9e-08 31.9 0.2 4.7e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KFQ90688.1 - 0.00019 21.7 0.1 0.00051 20.3 0.0 1.8 2 0 0 2 2 2 1 PDZ domain Adeno_E1A PF02703.14 KFQ90688.1 - 0.016 14.8 1.1 0.03 13.9 1.1 1.4 1 0 0 1 1 1 0 Early E1A protein Lar_restr_allev PF14354.6 KFQ90688.1 - 0.73 10.3 3.1 1.4 9.4 3.1 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.10 KFQ90688.1 - 1.8 8.8 5.2 14 5.9 3.4 2.8 1 1 2 3 3 3 0 Zinc ribbon domain DZR PF12773.7 KFQ90688.1 - 2.6 8.1 6.9 5.8 7.0 4.8 2.4 2 1 0 2 2 2 0 Double zinc ribbon SNF2_N PF00176.23 KFQ90689.1 - 7.9e-58 195.8 0.4 4.5e-57 193.4 0.3 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFQ90689.1 - 7.8e-22 77.7 0.2 3.7e-21 75.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFQ90689.1 - 7.8e-08 32.5 0.2 6.4e-07 29.5 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF1601 PF07671.11 KFQ90689.1 - 1.5 8.8 3.4 2.3 8.1 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1601) DUF4657 PF15552.6 KFQ90690.1 - 3e-06 27.0 1.9 3e-06 27.0 1.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4657) Zona_pellucida PF00100.23 KFQ90691.1 - 6.7e-56 189.9 0.6 9e-56 189.5 0.6 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Trefoil PF00088.18 KFQ90691.1 - 7.6e-10 38.5 5.6 2e-09 37.2 5.6 1.8 1 0 0 1 1 1 1 Trefoil (P-type) domain p450 PF00067.22 KFQ90692.1 - 4.9e-151 503.6 0.2 5.6e-151 503.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 CUB PF00431.20 KFQ90693.1 - 4.8e-188 612.7 9.1 2.8e-39 133.9 0.2 5.2 5 0 0 5 5 5 5 CUB domain Astacin PF01400.24 KFQ90693.1 - 1.3e-73 246.7 0.0 2.6e-73 245.7 0.0 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) FXa_inhibition PF14670.6 KFQ90693.1 - 1.1e-14 54.4 30.2 7.6e-09 35.7 11.4 3.4 4 0 0 4 4 2 2 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFQ90693.1 - 3.3e-12 46.1 7.6 3.9e-06 26.7 1.8 3.4 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF_CA PF07645.15 KFQ90693.1 - 9.2e-12 45.0 29.2 1.2e-06 28.6 9.0 2.8 2 0 0 2 2 2 2 Calcium-binding EGF domain EGF_3 PF12947.7 KFQ90693.1 - 1.3e-06 28.4 22.7 0.00088 19.4 3.6 3.0 2 0 0 2 2 2 2 EGF domain CUB_2 PF02408.20 KFQ90693.1 - 2.6e-06 27.2 3.0 0.17 11.7 0.1 5.2 5 0 0 5 5 5 2 CUB-like domain EGF PF00008.27 KFQ90693.1 - 3.7e-05 23.9 24.3 0.0048 17.2 8.3 3.0 2 0 0 2 2 2 2 EGF-like domain Reprolysin_4 PF13583.6 KFQ90693.1 - 0.00056 19.6 0.1 0.0013 18.5 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like hEGF PF12661.7 KFQ90693.1 - 0.00067 20.2 18.5 0.04 14.6 3.9 3.2 2 0 0 2 2 2 2 Human growth factor-like EGF Peptidase_M10 PF00413.24 KFQ90693.1 - 0.0029 17.5 0.7 1 9.2 0.1 2.8 2 0 0 2 2 2 2 Matrixin DUF3558 PF12079.8 KFQ90693.1 - 0.0072 16.3 5.5 3.2 7.7 0.0 4.1 3 1 0 4 4 4 2 Protein of unknown function (DUF3558) EMP70 PF02990.16 KFQ90694.1 - 4.8e-161 537.0 20.8 5.7e-161 536.7 20.8 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 DUF3169 PF11368.8 KFQ90694.1 - 0.63 9.5 19.6 0.58 9.6 4.8 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3169) EVC2_like PF12297.8 KFQ90694.1 - 0.75 8.4 1.8 15 4.2 0.0 2.2 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein DBB PF14545.6 KFQ90695.1 - 1.6e-52 177.1 0.0 2.6e-52 176.4 0.0 1.4 1 0 0 1 1 1 1 Dof, BCAP, and BANK (DBB) motif, TIR_3 PF18567.1 KFQ90695.1 - 3.6e-48 162.9 0.4 7.8e-48 161.8 0.4 1.6 1 0 0 1 1 1 1 Toll/interleukin-1 receptor domain SRP40_C PF05022.12 KFQ90696.1 - 4.7e-28 97.9 3.8 4.7e-28 97.9 3.8 2.9 3 0 0 3 3 3 1 SRP40, C-terminal domain UDPGT PF00201.18 KFQ90697.1 - 5.3e-107 358.7 0.0 6e-107 358.5 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KFQ90697.1 - 0.00063 19.8 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Pro_3_hydrox_C PF05373.11 KFQ90697.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal Homeodomain PF00046.29 KFQ90698.1 - 9.2e-23 79.9 9.4 1.5e-22 79.2 9.4 1.3 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 KFQ90698.1 - 5.2e-08 32.5 0.6 5.2e-08 32.5 0.6 2.3 2 0 0 2 2 2 1 OAR domain Homeobox_KN PF05920.11 KFQ90698.1 - 0.0037 17.1 0.6 0.0037 17.1 0.6 2.0 2 0 0 2 2 2 1 Homeobox KN domain Auxin_canalis PF05703.11 KFQ90698.1 - 5.1 6.9 10.4 1 9.2 6.1 1.8 2 0 0 2 2 2 0 Auxin canalisation Sec7 PF01369.20 KFQ90699.1 - 1.1e-65 220.7 0.2 2e-65 219.9 0.2 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KFQ90699.1 - 1.1e-25 90.4 6.2 1.1e-25 90.4 6.2 3.7 3 1 1 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF758 PF05527.11 KFQ90699.1 - 0.0098 15.9 0.1 0.028 14.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF758) DUF1045 PF06299.12 KFQ90699.1 - 0.036 14.0 0.0 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1045) Frag1 PF10277.9 KFQ90700.1 - 5e-46 157.0 11.3 5.6e-46 156.8 11.3 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.13 KFQ90700.1 - 2.7e-05 23.8 11.6 3.5e-05 23.5 11.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF998) DUF2768 PF10966.8 KFQ90700.1 - 2.2 8.8 7.6 0.63 10.5 2.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2768) RHD_DNA_bind PF00554.22 KFQ90701.1 - 5e-66 221.8 0.1 7.7e-66 221.2 0.1 1.3 1 0 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.5 KFQ90701.1 - 2.6e-38 130.2 0.0 4.9e-38 129.3 0.0 1.5 1 0 0 1 1 1 1 Rel homology dimerisation domain Ank_2 PF12796.7 KFQ90701.1 - 1.5e-29 102.4 1.8 3.7e-12 46.7 0.3 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFQ90701.1 - 4.5e-28 96.4 11.0 3.5e-05 24.1 0.0 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 KFQ90701.1 - 8.7e-28 93.3 3.5 0.0025 18.2 0.0 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.6 KFQ90701.1 - 4.5e-25 87.7 2.2 1.6e-08 34.9 0.0 5.2 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFQ90701.1 - 2.2e-24 85.2 1.5 5e-07 29.9 0.0 4.8 3 1 0 4 4 4 3 Ankyrin repeats (many copies) Death PF00531.22 KFQ90701.1 - 7.9e-07 29.2 0.1 3.7e-06 27.0 0.0 2.2 3 0 0 3 3 3 1 Death domain Sec7 PF01369.20 KFQ90702.1 - 3.8e-43 147.3 0.0 6.4e-43 146.6 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KFQ90702.1 - 2.3e-37 128.0 0.0 8.2e-37 126.2 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KFQ90702.1 - 1.4e-12 48.0 0.0 3.1e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 PH domain LRR_4 PF12799.7 KFQ90703.1 - 1.2e-09 38.2 1.0 0.02 15.3 0.0 5.1 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFQ90703.1 - 1.1e-07 31.3 6.4 0.38 10.9 0.0 6.2 6 0 0 6 6 6 3 Leucine Rich repeat F-box PF00646.33 KFQ90703.1 - 2.7e-06 27.1 1.3 2.7e-06 27.1 1.3 3.2 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KFQ90703.1 - 0.017 15.0 1.8 0.017 15.0 1.8 2.7 3 0 0 3 3 3 0 F-box-like DUF1699 PF08004.11 KFQ90703.1 - 0.12 12.1 0.5 3.6 7.3 0.0 3.1 1 1 2 4 4 4 0 Protein of unknown function (DUF1699) LRR_1 PF00560.33 KFQ90703.1 - 3.3 8.6 13.5 13 6.8 0.1 5.9 6 2 0 6 6 6 0 Leucine Rich Repeat CUE PF02845.16 KFQ90704.1 - 0.0012 18.5 0.1 0.0025 17.5 0.1 1.5 1 0 0 1 1 1 1 CUE domain PAX PF00292.18 KFQ90705.1 - 4.1e-76 252.9 0.5 6.7e-76 252.2 0.5 1.4 1 0 0 1 1 1 1 'Paired box' domain Pax2_C PF12403.8 KFQ90705.1 - 1.5e-54 182.9 14.5 3.2e-54 181.8 14.5 1.5 1 0 0 1 1 1 1 Paired-box protein 2 C terminal HTH_32 PF13565.6 KFQ90705.1 - 1.5e-05 25.5 0.1 0.018 15.7 0.0 2.7 2 1 1 3 3 3 2 Homeodomain-like domain HTH_23 PF13384.6 KFQ90705.1 - 4.5e-05 23.1 0.0 0.0001 22.0 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain Homeodomain PF00046.29 KFQ90705.1 - 0.0057 16.5 0.0 0.021 14.7 0.1 1.9 2 0 0 2 2 2 1 Homeodomain HTH_28 PF13518.6 KFQ90705.1 - 0.034 14.3 0.0 0.069 13.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_IS1 PF12759.7 KFQ90705.1 - 0.071 12.7 0.2 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 InsA C-terminal domain PLA2_inh PF02988.15 KFQ90706.1 - 3.7e-19 69.2 19.9 3.1e-17 63.0 9.2 2.1 2 0 0 2 2 2 2 Phospholipase A2 inhibitor UPAR_LY6 PF00021.21 KFQ90706.1 - 5.3e-10 39.9 21.7 3.9e-06 27.5 4.3 2.1 2 0 0 2 2 2 2 u-PAR/Ly-6 domain MIP PF00230.20 KFQ90707.1 - 6.8e-40 137.2 9.7 8.1e-40 136.9 9.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF3172 PF11371.8 KFQ90707.1 - 0.048 13.4 1.2 0.06 13.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3172) SMI1_KNR4 PF09346.10 KFQ90708.1 - 0.0062 16.9 0.0 0.011 16.2 0.0 1.5 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Pkinase PF00069.25 KFQ90709.1 - 5.2e-31 108.0 0.0 5.7e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ90709.1 - 2.3e-15 56.6 0.0 2.5e-15 56.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ90709.1 - 0.00054 19.4 0.0 0.0008 18.8 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFQ90709.1 - 0.032 13.2 0.0 0.034 13.1 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KFQ90709.1 - 0.11 12.4 0.1 0.13 12.1 0.1 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family DPM2 PF07297.12 KFQ90710.1 - 1.2e-17 63.9 0.1 1.4e-17 63.8 0.1 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) TMEM154 PF15102.6 KFQ90710.1 - 0.036 14.0 0.1 0.043 13.7 0.1 1.0 1 0 0 1 1 1 0 TMEM154 protein family S1FA PF04689.13 KFQ90710.1 - 0.12 12.5 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 DNA binding protein S1FA LAX PF15681.5 KFQ90710.1 - 0.26 10.1 0.2 0.29 9.9 0.2 1.0 1 0 0 1 1 1 0 Lymphocyte activation family X NT-C2 PF10358.9 KFQ90711.1 - 7.3e-30 103.6 0.0 1.6e-29 102.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Mito_carr PF00153.27 KFQ90712.1 - 5.9e-74 244.1 2.0 5.5e-25 87.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KFQ90712.1 - 1.2e-14 54.4 2.4 8.2e-11 42.2 0.4 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFQ90712.1 - 9.1e-14 49.9 2.9 0.0014 18.1 0.2 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KFQ90712.1 - 7.9e-12 44.1 3.4 0.00029 20.5 0.1 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 KFQ90712.1 - 4.3e-08 32.9 1.6 0.0044 16.8 0.1 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KFQ90712.1 - 1.5e-06 27.4 2.7 0.0022 17.4 0.1 3.3 3 1 0 3 3 3 2 EF hand EF-hand_10 PF14788.6 KFQ90712.1 - 0.00062 19.6 0.9 1.2 9.1 0.0 3.5 2 1 1 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 KFQ90712.1 - 0.0017 18.7 0.7 0.0036 17.6 0.7 1.5 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFQ90712.1 - 0.076 13.0 2.7 0.75 9.8 0.6 2.4 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF1002 PF06207.11 KFQ90712.1 - 0.11 12.0 0.2 0.18 11.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) DUF2624 PF11116.8 KFQ90712.1 - 0.13 13.1 0.0 0.28 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) ApoM PF11032.8 KFQ90713.1 - 4.6e-11 42.7 0.0 5.5e-11 42.5 0.0 1.0 1 0 0 1 1 1 1 ApoM domain Lipocalin PF00061.23 KFQ90713.1 - 1.1e-05 25.7 0.0 3.8e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Laminin_EGF PF00053.24 KFQ90714.1 - 5.2e-41 138.6 97.6 2.6e-10 40.3 13.3 5.3 4 1 1 5 5 5 5 Laminin EGF domain TMEM154 PF15102.6 KFQ90714.1 - 0.0037 17.2 0.4 0.006 16.5 0.4 1.2 1 0 0 1 1 1 1 TMEM154 protein family DUF3262 PF11660.8 KFQ90714.1 - 0.079 13.4 0.5 0.14 12.6 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) Stevor PF17410.2 KFQ90714.1 - 0.1 12.1 0.2 0.16 11.4 0.2 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame MACPF PF01823.19 KFQ90716.1 - 3.8e-07 30.4 0.1 1.4e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 MAC/Perforin domain RhoGAP-FF1 PF16512.5 KFQ90716.1 - 0.096 13.4 0.1 0.81 10.4 0.1 2.4 2 0 0 2 2 2 0 p190-A and -B Rho GAPs FF domain LRR_8 PF13855.6 KFQ90719.1 - 2.1e-45 152.3 60.5 5.6e-13 48.4 1.7 9.9 6 2 5 11 11 11 9 Leucine rich repeat TIR PF01582.20 KFQ90719.1 - 3.1e-21 76.0 0.0 6.3e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 KFQ90719.1 - 2.2e-16 59.7 62.9 3e-05 24.3 1.6 11.0 6 4 8 14 14 14 11 Leucine Rich repeats (2 copies) TIR_2 PF13676.6 KFQ90719.1 - 2.5e-11 44.2 0.2 1.3e-10 41.9 0.0 2.3 3 0 0 3 3 3 1 TIR domain LRR_5 PF13306.6 KFQ90719.1 - 4.2e-11 42.9 26.6 1.3e-07 31.6 0.2 5.5 3 2 2 5 5 5 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFQ90719.1 - 2.3e-05 24.3 45.6 0.91 10.3 0.7 13.1 13 1 0 13 13 13 3 Leucine Rich Repeat LRR_9 PF14580.6 KFQ90719.1 - 0.0001 21.9 16.9 0.033 13.7 0.6 4.2 3 1 1 4 4 4 2 Leucine-rich repeat Annexin_like PF18411.1 KFQ90720.1 - 1.8e-45 153.2 0.2 6.5e-45 151.3 0.2 2.1 1 1 0 1 1 1 1 Annexin-like domain ASTN_2_hairpin PF18577.1 KFQ90720.1 - 5.4e-28 96.8 0.7 1.3e-27 95.6 0.7 1.7 1 0 0 1 1 1 1 Astrotactin-2 C-terminal beta-hairpin domain FXa_inhibition PF14670.6 KFQ90720.1 - 3.7e-11 43.1 43.7 1.1e-10 41.6 4.0 4.2 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site MACPF PF01823.19 KFQ90720.1 - 2.9e-06 27.5 0.0 2.2e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 MAC/Perforin domain cEGF PF12662.7 KFQ90720.1 - 0.0027 17.6 5.1 0.14 12.1 0.4 3.3 2 0 0 2 2 2 2 Complement Clr-like EGF-like Herpes_gE PF02480.16 KFQ90720.1 - 0.025 13.4 0.0 0.058 12.1 0.0 1.6 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E fn3 PF00041.21 KFQ90720.1 - 0.028 14.8 0.0 0.11 12.9 0.0 2.0 1 1 0 1 1 1 0 Fibronectin type III domain NHL PF01436.21 KFQ90721.1 - 2.8e-31 105.9 2.1 1.1e-05 25.3 0.0 5.9 5 0 0 5 5 5 5 NHL repeat zf-RING_UBOX PF13445.6 KFQ90721.1 - 3.4e-10 39.8 7.4 3.4e-10 39.8 7.4 2.7 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFQ90721.1 - 5.5e-09 36.2 9.2 5.5e-09 36.2 9.2 3.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KFQ90721.1 - 4.8e-07 29.6 9.1 4.8e-07 29.6 9.1 3.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFQ90721.1 - 2.6e-06 27.2 10.4 2.6e-06 27.2 10.4 3.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 KFQ90721.1 - 4e-05 23.7 3.5 4e-05 23.7 3.5 3.2 3 1 0 3 3 2 1 B-box zinc finger zf-C3HC4_4 PF15227.6 KFQ90721.1 - 0.00012 22.1 8.6 0.00012 22.1 8.6 3.2 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 KFQ90721.1 - 0.00012 22.0 0.8 0.00012 22.0 0.8 2.4 3 0 0 3 3 3 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_2 PF13923.6 KFQ90721.1 - 0.00014 21.7 9.7 0.00014 21.7 9.7 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KFQ90721.1 - 0.00035 20.3 5.8 0.00035 20.3 5.8 2.7 3 0 0 3 3 2 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KFQ90721.1 - 0.001 18.9 9.8 0.001 18.9 9.8 3.9 4 1 1 5 5 4 1 Prokaryotic RING finger family 4 SGL PF08450.12 KFQ90721.1 - 0.0019 17.8 0.0 12 5.4 0.0 3.8 2 1 2 4 4 4 0 SMP-30/Gluconolactonase/LRE-like region OmpH PF03938.14 KFQ90721.1 - 0.0064 16.8 3.8 0.01 16.2 3.8 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) zf-RING_11 PF17123.5 KFQ90721.1 - 0.07 12.9 6.7 0.23 11.2 6.7 2.0 1 0 0 1 1 1 0 RING-like zinc finger FAM184 PF15665.5 KFQ90721.1 - 0.083 12.7 4.3 0.13 12.0 4.3 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Zn_Tnp_IS1595 PF12760.7 KFQ90721.1 - 0.51 10.4 0.0 0.51 10.4 0.0 3.5 4 0 0 4 4 3 0 Transposase zinc-ribbon domain FYVE PF01363.21 KFQ90721.1 - 1.7 8.9 27.2 1.3e+03 -0.4 20.4 3.0 2 1 0 2 2 1 0 FYVE zinc finger CEBP_ZZ PF16366.5 KFQ90721.1 - 1.7 8.9 12.1 3 8.2 1.8 3.5 3 0 0 3 3 3 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Rad50_zn_hook PF04423.14 KFQ90721.1 - 3.6 7.5 7.1 1.1 9.2 0.3 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif Laminin_G_3 PF13385.6 KFQ90722.1 - 1.4e-21 77.2 0.0 2.7e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Sushi PF00084.20 KFQ90722.1 - 2.6e-21 76.0 48.0 1.6e-07 31.8 3.7 8.7 7 2 1 8 8 8 4 Sushi repeat (SCR repeat) Peptidase_M43 PF05572.13 KFQ90722.1 - 7.3e-08 32.5 0.8 2.2e-07 30.9 0.1 2.3 1 1 1 2 2 2 1 Pregnancy-associated plasma protein-A Notch PF00066.17 KFQ90722.1 - 0.0004 20.8 5.0 0.0004 20.8 5.0 6.8 6 0 0 6 6 6 3 LNR domain Reprolysin_3 PF13582.6 KFQ90722.1 - 0.005 17.4 0.2 0.013 16.0 0.2 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFQ90722.1 - 0.075 12.7 0.1 0.23 11.1 0.1 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like fn3 PF00041.21 KFQ90722.1 - 0.32 11.4 1.6 40 4.6 0.1 3.4 3 0 0 3 3 3 0 Fibronectin type III domain Peptidase_M10 PF00413.24 KFQ90722.1 - 0.63 9.9 1.9 1.7 8.5 1.9 1.6 1 0 0 1 1 1 0 Matrixin fn3 PF00041.21 KFQ90724.1 - 3.7e-140 456.6 24.1 3.7e-16 59.2 0.0 9.4 9 0 0 9 9 9 9 Fibronectin type III domain Fibrinogen_C PF00147.18 KFQ90724.1 - 9.9e-86 287.1 6.9 1.6e-85 286.4 6.9 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain EGF_Tenascin PF18720.1 KFQ90724.1 - 4.7e-16 58.4 66.9 6.5e-07 29.3 5.6 5.6 5 0 0 5 5 5 4 Tenascin EGF domain EGF_2 PF07974.13 KFQ90724.1 - 1.5e-15 57.3 90.1 0.00036 20.8 15.1 5.6 5 0 0 5 5 5 5 EGF-like domain Pur_ac_phosph_N PF16656.5 KFQ90724.1 - 1.1e-14 54.8 20.4 0.00048 20.7 0.7 10.1 8 6 0 8 8 7 3 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFQ90724.1 - 5.1e-14 52.4 0.0 0.52 10.7 0.1 8.0 9 0 0 9 9 9 4 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 KFQ90724.1 - 1.9e-11 44.2 0.3 0.14 12.6 0.0 7.2 7 0 0 7 7 7 1 Uncharacterised conserved protein (DUF2369) DUF4998 PF16389.5 KFQ90724.1 - 1.1e-08 34.9 0.1 0.28 10.8 0.0 6.0 6 1 0 7 7 7 2 Domain of unknown function fn3_2 PF16893.5 KFQ90724.1 - 4.8e-08 33.0 0.2 0.98 9.6 0.0 6.8 8 0 0 8 8 8 2 Fibronectin type III domain EGF PF00008.27 KFQ90724.1 - 8.7e-08 32.3 75.7 0.026 14.8 10.1 5.8 5 0 0 5 5 5 4 EGF-like domain DUF4959 PF16323.5 KFQ90724.1 - 1.2e-05 25.5 0.1 3.7 7.9 0.0 5.8 5 1 1 6 6 6 1 Domain of unknown function (DUF4959) Big_5 PF13205.6 KFQ90724.1 - 0.0002 22.0 10.1 0.082 13.6 0.4 5.6 3 1 1 5 5 5 2 Bacterial Ig-like domain Big_10 PF17964.1 KFQ90724.1 - 0.015 15.3 1.5 7.9 6.4 0.0 4.0 4 0 0 4 4 4 0 Bacterial Ig domain DUF4945 PF16303.5 KFQ90724.1 - 0.53 10.2 5.2 1.1e+02 2.8 0.1 5.3 6 1 1 7 7 7 0 Domain of unknown function (DUF4945) hEGF PF12661.7 KFQ90724.1 - 0.79 10.5 58.6 0.067 13.8 5.8 5.8 5 0 0 5 5 5 0 Human growth factor-like EGF TNF PF00229.18 KFQ90725.1 - 7.3e-14 51.8 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family DUF2749 PF10907.8 KFQ90725.1 - 0.16 12.2 0.3 0.28 11.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) TNF PF00229.18 KFQ90726.1 - 6.7e-37 126.3 0.1 1.1e-36 125.6 0.1 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family LppA PF16708.5 KFQ90726.1 - 0.041 13.8 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipoprotein confined to pathogenic Mycobacterium DUF2126 PF09899.9 KFQ90726.1 - 0.17 9.9 0.0 0.2 9.7 0.0 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF4481 PF14800.6 KFQ90727.1 - 8.6e-49 166.6 2.7 9.3e-49 166.5 2.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4481) DUF2070 PF09843.9 KFQ90727.1 - 0.01 14.2 0.8 0.011 14.1 0.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) V-ATPase_G PF03179.15 KFQ90728.1 - 3.6e-25 88.5 8.0 4.1e-25 88.3 8.0 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3924 PF13062.6 KFQ90728.1 - 0.067 13.2 0.2 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3924) OmpH PF03938.14 KFQ90728.1 - 0.14 12.5 6.5 0.17 12.2 6.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RRF PF01765.19 KFQ90728.1 - 0.3 11.0 4.9 0.4 10.6 4.9 1.1 1 0 0 1 1 1 0 Ribosome recycling factor PDZ PF00595.24 KFQ90729.1 - 2e-45 153.1 3.3 2.2e-19 69.6 0.1 3.4 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 KFQ90729.1 - 9.8e-28 95.8 0.1 3.2e-09 36.5 0.0 3.8 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 KFQ90729.1 - 1.1e-14 54.5 0.1 0.00017 21.8 0.0 3.6 3 0 0 3 3 3 3 PDZ domain Tricorn_PDZ PF14685.6 KFQ90729.1 - 0.014 15.3 2.2 5.1 7.1 0.1 3.7 4 0 0 4 4 4 0 Tricorn protease PDZ domain PDZ_4 PF17816.1 KFQ90729.1 - 0.034 14.5 0.0 7.1 7.1 0.0 2.8 3 0 0 3 3 3 0 PDZ domain Sec1 PF00995.23 KFQ90730.1 - 1.1e-15 57.9 0.0 1.2e-15 57.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.23 KFQ90731.1 - 1.1e-103 348.4 5.3 1.3e-103 348.3 5.3 1.0 1 0 0 1 1 1 1 Sec1 family YlbD_coat PF14071.6 KFQ90731.1 - 0.029 14.6 0.8 0.071 13.4 0.8 1.6 1 0 0 1 1 1 0 Putative coat protein DUF365 PF04033.12 KFQ90731.1 - 0.11 12.7 0.2 1.7 9.0 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF365) Ctr PF04145.15 KFQ90732.1 - 4.6e-18 66.3 7.9 1.4e-17 64.6 7.9 1.7 1 1 0 1 1 1 1 Ctr copper transporter family Ion_trans PF00520.31 KFQ90733.1 - 1.9e-250 826.4 78.2 1.5e-65 220.8 26.2 4.1 4 0 0 4 4 4 4 Ion transport protein Ca_chan_IQ PF08763.11 KFQ90733.1 - 2.1e-32 111.2 0.0 5.3e-32 109.8 0.0 1.8 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain GPHH PF16905.5 KFQ90733.1 - 1.2e-30 105.0 0.2 4.5e-30 103.2 0.3 2.0 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 KFQ90733.1 - 3.7e-08 32.5 85.8 3.5e-06 26.0 10.4 9.5 6 4 3 9 9 9 4 Polycystin cation channel Tmemb_9 PF05434.11 KFQ90733.1 - 0.17 11.8 1.6 11 5.9 0.0 3.1 2 0 0 2 2 2 0 TMEM9 Arrestin_C PF02752.22 KFQ90734.1 - 1.1e-21 77.7 0.1 1e-19 71.3 0.1 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KFQ90734.1 - 5.2e-14 52.5 0.1 3.2e-13 50.0 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KFQ90734.1 - 0.062 13.0 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Arrestin_N terminal like Gln-synt_C PF00120.24 KFQ90735.1 - 9.1e-16 57.8 0.0 1.8e-11 43.6 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KFQ90735.1 - 3.7e-13 49.0 0.0 7e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain COBRA1 PF06209.13 KFQ90736.1 - 5.3e-253 840.0 3.6 6.5e-253 839.7 3.6 1.1 1 0 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) Nnf1 PF03980.14 KFQ90736.1 - 0.61 10.5 2.7 0.41 11.0 0.3 2.0 2 0 0 2 2 2 0 Nnf1 GDA1_CD39 PF01150.17 KFQ90737.1 - 1.4e-42 145.9 0.0 1.7e-42 145.6 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family zf-CSL PF05207.13 KFQ90737.1 - 0.017 14.8 0.4 3.4 7.5 0.1 2.3 2 0 0 2 2 2 0 CSL zinc finger Tubulin PF00091.25 KFQ90738.1 - 6.9e-53 179.8 0.0 1.2e-52 179.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFQ90738.1 - 1.9e-43 147.6 0.1 3.1e-43 147.0 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFQ90738.1 - 0.0058 16.3 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KFQ90738.1 - 0.012 14.8 0.1 0.027 13.7 0.0 1.5 2 0 0 2 2 2 0 Tubulin like Pkinase_Tyr PF07714.17 KFQ90739.1 - 4.8e-84 281.7 0.0 6.5e-84 281.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ90739.1 - 1.5e-41 142.5 0.0 1.2e-40 139.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain TMEM154 PF15102.6 KFQ90739.1 - 0.003 17.5 0.4 0.0051 16.7 0.4 1.3 1 0 0 1 1 1 1 TMEM154 protein family F5_F8_type_C PF00754.25 KFQ90739.1 - 0.0075 16.4 0.0 0.026 14.7 0.0 2.0 2 0 0 2 2 2 1 F5/8 type C domain Haspin_kinase PF12330.8 KFQ90739.1 - 0.018 14.0 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF2062 PF09835.9 KFQ90739.1 - 0.026 14.4 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Mid2 PF04478.12 KFQ90739.1 - 0.067 13.0 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF3377 PF11857.8 KFQ90739.1 - 0.11 12.5 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Stevor PF17410.2 KFQ90739.1 - 0.19 11.2 0.5 0.33 10.5 0.5 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame F5_F8_type_C PF00754.25 KFQ90740.1 - 9e-14 51.7 0.1 1.1e-13 51.4 0.1 1.0 1 0 0 1 1 1 1 F5/8 type C domain Torsin PF06309.11 KFQ90741.1 - 2e-14 53.8 0.1 4.9e-14 52.5 0.0 1.6 2 0 0 2 2 2 1 Torsin AAA_16 PF13191.6 KFQ90741.1 - 5.5e-05 23.6 0.0 0.028 14.8 0.0 3.3 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KFQ90741.1 - 0.0053 17.0 0.1 1.3 9.3 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFQ90741.1 - 0.0078 16.8 0.0 0.029 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KFQ90741.1 - 0.03 14.7 0.0 0.078 13.4 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 KFQ90741.1 - 0.056 12.7 0.0 0.11 11.7 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain IstB_IS21 PF01695.17 KFQ90741.1 - 0.087 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Cullin PF00888.22 KFQ90742.1 - 1.6e-30 106.3 2.4 1.6e-30 106.3 2.4 1.9 2 0 0 2 2 2 1 Cullin family ANAPC2 PF08672.11 KFQ90742.1 - 3.8e-24 84.9 1.3 2e-23 82.6 0.7 2.7 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 Cor1 PF04803.12 KFQ90742.1 - 0.048 13.9 7.4 2.1 8.5 1.1 3.5 3 0 0 3 3 3 0 Cor1/Xlr/Xmr conserved region Phostensin PF13914.6 KFQ90743.1 - 7.5e-43 146.5 9.4 1.3e-41 142.4 0.7 2.7 3 0 0 3 3 3 2 Phostensin PP1-binding and SH3-binding region LZ_Tnp_IS481 PF13011.6 KFQ90743.1 - 1.5 9.4 3.1 29 5.3 0.9 2.6 2 0 0 2 2 2 0 leucine-zipper of insertion element IS481 BSP_II PF05432.11 KFQ90743.1 - 6.3 6.4 18.4 0.11 12.2 6.6 2.1 1 1 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF4347 PF14252.6 KFQ90744.1 - 0.00029 20.7 0.0 0.0005 20.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4347) IQ PF00612.27 KFQ90744.1 - 0.00075 19.1 6.0 0.086 12.7 0.2 3.4 3 0 0 3 3 3 2 IQ calmodulin-binding motif cNMP_binding PF00027.29 KFQ90745.1 - 1.6e-51 172.3 0.2 4.7e-18 65.0 0.0 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Patatin PF01734.22 KFQ90745.1 - 8.1e-25 88.2 0.2 1.6e-24 87.2 0.2 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase TNFR_16_TM PF18422.1 KFQ90745.1 - 0.2 11.6 0.3 0.51 10.3 0.3 1.6 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF347 PF03988.12 KFQ90745.1 - 0.32 11.2 3.9 7.5 6.8 2.1 2.4 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) VPDSG-CTERM PF18205.1 KFQ90745.1 - 0.36 10.7 1.6 1.1 9.2 1.6 1.9 1 0 0 1 1 1 0 VPDSG-CTERM motif MRP-L27 PF09809.9 KFQ90746.1 - 9.6e-44 147.8 0.1 1.1e-43 147.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 WD40 PF00400.32 KFQ90747.1 - 8.2e-06 26.5 7.7 0.11 13.4 0.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat zf-MYND PF01753.18 KFQ90748.1 - 2.8e-07 30.5 15.2 4.4e-07 29.9 15.2 1.4 1 0 0 1 1 1 1 MYND finger HNH_3 PF13392.6 KFQ90748.1 - 3.1e-05 23.6 0.2 5.9e-05 22.7 0.2 1.4 1 0 0 1 1 1 1 HNH endonuclease Ribosomal_L11 PF00298.19 KFQ90751.1 - 5.9e-18 65.1 0.2 8.2e-18 64.7 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KFQ90751.1 - 1e-10 41.3 0.0 1.7e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain FKBP_C PF00254.28 KFQ90752.1 - 4.4e-26 91.0 0.0 1.2e-25 89.7 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase WH1 PF00568.23 KFQ90752.1 - 0.0018 18.2 0.2 0.0045 16.9 0.2 1.6 1 0 0 1 1 1 1 WH1 domain FPP PF05911.11 KFQ90752.1 - 0.24 9.5 57.3 0.0089 14.3 50.7 1.7 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil Filament PF00038.21 KFQ90752.1 - 0.55 9.8 65.8 0.059 13.0 45.4 3.4 1 1 2 3 3 3 0 Intermediate filament protein NPV_P10 PF05531.12 KFQ90752.1 - 0.6 10.6 24.2 0.89 10.1 0.3 5.4 2 1 5 7 7 7 0 Nucleopolyhedrovirus P10 protein GAS PF13851.6 KFQ90752.1 - 2.7 7.3 75.2 0.12 11.7 36.9 3.5 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding Ctr PF04145.15 KFQ90753.1 - 2.8e-33 115.6 6.5 6.1e-33 114.5 6.5 1.5 1 1 0 1 1 1 1 Ctr copper transporter family WD40 PF00400.32 KFQ90754.1 - 1.7e-36 123.5 23.0 1.1e-08 35.6 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ90754.1 - 1.6e-14 54.0 0.1 0.0085 16.4 0.0 5.2 3 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 KFQ90754.1 - 2.8e-14 52.3 0.7 2.8e-14 52.3 0.7 2.3 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like WD40_like PF17005.5 KFQ90754.1 - 0.00058 19.3 0.0 0.0025 17.2 0.0 2.0 2 0 0 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 KFQ90754.1 - 0.0023 17.0 0.3 2.6 6.9 0.1 3.5 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFQ90754.1 - 0.0062 15.2 0.9 2.1 6.9 0.0 3.8 1 1 3 4 4 4 1 Nucleoporin Nup120/160 DUF3776 PF12618.8 KFQ90754.1 - 0.31 11.6 2.2 3.9 8.1 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3776) WD40 PF00400.32 KFQ90755.1 - 8.1e-26 89.8 13.3 2.2e-06 28.2 0.5 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ90755.1 - 3e-06 27.4 0.0 0.056 13.7 0.0 3.3 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFQ90755.1 - 0.00017 20.4 6.8 0.82 8.2 0.2 4.5 1 1 2 4 4 4 2 Nucleoporin Nup120/160 HAD_2 PF13419.6 KFQ90756.1 - 1.3e-17 64.4 0.0 1.5e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFQ90756.1 - 6.2e-14 52.8 0.0 7.5e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFQ90756.1 - 2.8e-08 33.7 0.0 5.3e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like TGS PF02824.21 KFQ90756.1 - 0.2 11.7 0.0 0.42 10.7 0.0 1.5 1 0 0 1 1 1 0 TGS domain ALAD PF00490.21 KFQ90757.1 - 5e-117 390.6 0.0 6.1e-117 390.3 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase CBFD_NFYB_HMF PF00808.23 KFQ90758.1 - 2.8e-07 30.7 0.0 5.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SpoU_methylase PF00588.19 KFQ90758.1 - 0.0068 16.6 0.0 0.0085 16.3 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family Histone PF00125.24 KFQ90758.1 - 0.017 15.5 5.9 0.069 13.5 0.0 2.1 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 DUF4746 PF15928.5 KFQ90758.1 - 0.061 12.7 8.0 0.062 12.7 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Myc_N PF01056.18 KFQ90758.1 - 0.077 12.9 6.4 0.073 13.0 6.4 1.1 1 0 0 1 1 1 0 Myc amino-terminal region BUD22 PF09073.10 KFQ90758.1 - 0.079 12.3 15.0 0.086 12.2 15.0 1.1 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.14 KFQ90758.1 - 0.11 12.3 10.7 0.12 12.2 10.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOA36 PF06524.12 KFQ90758.1 - 0.22 10.8 11.3 0.22 10.8 11.3 1.1 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.12 KFQ90758.1 - 0.31 10.4 16.1 0.36 10.2 16.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Afi1 PF07792.12 KFQ90758.1 - 0.35 11.3 12.3 0.49 10.9 12.3 1.3 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CDC45 PF02724.14 KFQ90758.1 - 0.63 8.3 9.8 0.59 8.4 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2956 PF11169.8 KFQ90758.1 - 0.89 9.8 8.1 1.4 9.2 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) DUF913 PF06025.12 KFQ90758.1 - 1.1 8.2 4.1 0.97 8.3 4.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) V_ATPase_I PF01496.19 KFQ90758.1 - 1.3 6.9 4.2 1.2 7.0 4.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Vfa1 PF08432.10 KFQ90758.1 - 1.3 9.3 14.1 1.5 9.1 14.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RPN2_C PF18004.1 KFQ90758.1 - 1.3 8.9 11.9 1.4 8.8 11.9 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Presenilin PF01080.17 KFQ90758.1 - 1.4 7.6 5.8 1.4 7.6 5.8 1.1 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 KFQ90758.1 - 1.5 8.5 3.7 1.5 8.6 3.7 1.2 1 0 0 1 1 1 0 Connexin DNA_pol_phi PF04931.13 KFQ90758.1 - 1.7 6.7 21.8 2 6.4 21.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi NPR3 PF03666.13 KFQ90758.1 - 2.8 6.6 8.0 3.1 6.5 8.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 C2 PF00168.30 KFQ90759.1 - 2e-19 69.8 0.1 3e-19 69.2 0.1 1.3 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.6 KFQ90759.1 - 0.0046 16.5 0.1 0.0056 16.3 0.1 1.4 1 1 0 1 1 1 1 CEP76 C2 domain B9-C2 PF07162.11 KFQ90759.1 - 0.073 13.3 0.1 0.12 12.6 0.0 1.4 2 0 0 2 2 2 0 Ciliary basal body-associated, B9 protein RGS PF00615.19 KFQ90760.1 - 6e-39 133.0 4.1 6.7e-39 132.8 4.1 1.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain Rod_C PF10493.9 KFQ90760.1 - 0.036 12.4 1.0 0.041 12.3 1.0 1.0 1 0 0 1 1 1 0 Rough deal protein C-terminal region Inhibitor_I10 PF12559.8 KFQ90760.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Serine endopeptidase inhibitors zf-C2H2_4 PF13894.6 KFQ90762.1 - 1.5e-09 37.9 23.4 0.028 15.2 2.3 5.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KFQ90762.1 - 1.2e-07 31.8 28.3 0.13 12.8 2.9 5.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type Dimer_Tnp_hAT PF05699.14 KFQ90762.1 - 2.1e-05 24.2 0.2 6.2e-05 22.7 0.2 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-C2H2_3rep PF18868.1 KFQ90762.1 - 0.013 16.2 5.7 0.64 10.7 0.0 3.9 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats C1_2 PF03107.16 KFQ90762.1 - 0.059 13.7 26.8 0.38 11.1 2.6 5.3 5 0 0 5 5 5 0 C1 domain DBD_Tnp_Hermes PF10683.9 KFQ90762.1 - 0.075 12.7 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain DUF4413 PF14372.6 KFQ90762.1 - 0.091 13.1 0.0 0.26 11.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) zf_UBZ PF18439.1 KFQ90762.1 - 0.15 11.7 14.1 0.53 9.9 1.3 4.5 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-H2C2_2 PF13465.6 KFQ90762.1 - 2.8 8.5 24.0 1.2 9.7 0.1 5.3 6 0 0 6 6 6 0 Zinc-finger double domain zf-BED PF02892.15 KFQ90762.1 - 5.4 7.1 24.6 1.9 8.6 2.9 4.9 5 0 0 5 5 5 0 BED zinc finger Rieske PF00355.26 KFQ90763.1 - 9.5e-16 57.5 0.1 1.8e-15 56.7 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KFQ90763.1 - 2.1e-05 24.4 0.0 3.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Lig_chan PF00060.26 KFQ90764.1 - 1.2e-38 132.3 0.1 2e-38 131.6 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.28 KFQ90764.1 - 3.3e-33 115.2 0.0 3.2e-31 108.7 0.0 2.3 1 1 0 1 1 1 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.9 KFQ90764.1 - 6.8e-32 110.1 0.1 3.8e-30 104.4 0.0 2.5 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFQ90764.1 - 2e-19 70.0 0.0 4.4e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 CaM_bdg_C0 PF10562.9 KFQ90764.1 - 9.6e-14 51.1 3.9 2.2e-13 50.0 3.9 1.7 1 0 0 1 1 1 1 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit Ion_trans_2 PF07885.16 KFQ90764.1 - 0.023 14.7 0.6 0.063 13.2 0.6 1.7 1 0 0 1 1 1 0 Ion channel Peripla_BP_6 PF13458.6 KFQ90764.1 - 0.028 14.1 0.0 0.74 9.4 0.0 2.2 2 0 0 2 2 2 0 Periplasmic binding protein zf-RING_UBOX PF13445.6 KFQ90765.1 - 9.7e-09 35.1 3.6 9.7e-09 35.1 3.6 2.1 2 2 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFQ90765.1 - 3e-07 30.7 10.0 3e-07 30.7 10.0 2.3 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KFQ90765.1 - 1.1e-05 25.3 8.8 1.1e-05 25.3 8.8 2.2 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFQ90765.1 - 0.00021 21.4 7.9 0.00021 21.4 7.9 2.5 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KFQ90765.1 - 0.00065 19.5 8.8 0.00065 19.5 8.8 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFQ90765.1 - 0.0026 17.6 10.4 0.0026 17.6 10.4 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFQ90766.1 - 0.0032 17.4 13.8 0.0032 17.4 13.8 3.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFQ90766.1 - 0.0053 17.1 11.8 0.0053 17.1 11.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KFQ90766.1 - 0.014 15.5 12.6 0.014 15.5 12.6 2.8 2 1 0 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.6 KFQ90766.1 - 0.014 15.2 13.7 0.014 15.2 13.7 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 GcpE PF04551.14 KFQ90766.1 - 0.36 9.8 5.6 1.3 8.0 5.6 1.8 1 1 0 1 1 1 0 GcpE protein zf-C3HC4 PF00097.25 KFQ90766.1 - 1.6 8.7 22.7 0.047 13.6 14.6 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS1595 PF12760.7 KFQ90766.1 - 3.7 7.6 13.5 3.2 7.8 2.2 3.0 2 1 1 3 3 3 0 Transposase zinc-ribbon domain ADK_lid PF05191.14 KFQ90766.1 - 9.4 6.3 9.5 0.47 10.5 1.5 2.7 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-RING_2 PF13639.6 KFQ90767.1 - 2.9e-09 37.1 6.1 5.2e-09 36.3 6.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFQ90767.1 - 4.8e-09 36.0 5.8 7.1e-09 35.5 5.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFQ90767.1 - 2.5e-08 33.8 2.4 2.5e-08 33.8 2.4 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFQ90767.1 - 2.7e-08 33.5 5.7 4.7e-08 32.8 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFQ90767.1 - 7.1e-08 32.2 7.6 1.9e-07 30.8 7.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFQ90767.1 - 8.3e-07 29.1 2.9 2.2e-06 27.7 2.9 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KFQ90767.1 - 1.3e-06 28.1 6.7 2.7e-06 27.1 6.7 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KFQ90767.1 - 8.3e-06 25.6 8.9 0.00031 20.5 9.4 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFQ90767.1 - 0.0019 18.5 4.2 0.0022 18.2 3.6 1.5 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFQ90767.1 - 0.0025 17.8 2.1 0.0036 17.3 2.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KFQ90767.1 - 0.0029 17.4 11.3 0.036 13.9 11.6 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Sec23_Sec24 PF04810.15 KFQ90767.1 - 0.022 14.8 2.4 0.082 13.0 0.6 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger NMD3 PF04981.13 KFQ90767.1 - 0.05 13.1 2.4 0.056 12.9 2.4 1.0 1 0 0 1 1 1 0 NMD3 family zf-RING_11 PF17123.5 KFQ90767.1 - 0.085 12.6 0.4 0.085 12.6 0.4 2.4 3 0 0 3 3 3 0 RING-like zinc finger zf-P11 PF03854.14 KFQ90767.1 - 0.1 12.3 11.5 0.45 10.2 5.2 2.8 1 1 1 2 2 2 0 P-11 zinc finger zf-WRNIP1_ubi PF18279.1 KFQ90767.1 - 0.11 13.2 3.1 0.81 10.5 0.3 2.6 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Gin PF10764.9 KFQ90767.1 - 0.2 11.7 0.3 0.2 11.7 0.3 2.2 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin Zn-C2H2_12 PF18112.1 KFQ90767.1 - 0.2 12.1 2.9 3.9 8.0 0.1 2.4 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain DZR PF12773.7 KFQ90767.1 - 0.23 11.5 6.8 2.4 8.3 6.8 2.1 1 1 0 1 1 1 0 Double zinc ribbon DUF4428 PF14471.6 KFQ90767.1 - 0.32 10.9 6.4 0.46 10.4 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) Baculo_IE-1 PF05290.11 KFQ90767.1 - 0.58 10.1 3.1 0.77 9.7 3.1 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) YacG PF03884.14 KFQ90767.1 - 0.76 9.6 6.8 2.9 7.7 1.0 2.3 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG zf-RING_10 PF16685.5 KFQ90767.1 - 1.2 9.4 7.3 2.9 8.1 7.3 1.8 1 1 0 1 1 1 0 zinc RING finger of MSL2 DUF3090 PF11290.8 KFQ90767.1 - 1.6 8.5 4.3 5.3 6.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) RecR PF02132.15 KFQ90767.1 - 5.8 6.6 9.8 4.1 7.0 0.7 2.9 2 1 0 2 2 2 0 RecR protein zf-C2H2_4 PF13894.6 KFQ90767.1 - 6.4 7.9 7.9 20 6.4 2.2 2.9 2 1 0 2 2 2 0 C2H2-type zinc finger FAD_binding_1 PF00667.20 KFQ90768.1 - 1.2e-47 162.4 0.0 2e-47 161.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFQ90768.1 - 6.2e-32 110.8 0.0 9.5e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KFQ90768.1 - 6.3e-17 62.2 0.0 1.2e-16 61.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Tmemb_185A PF10269.9 KFQ90769.1 - 2.4e-06 27.5 12.6 4.9e-06 26.4 11.1 1.8 1 1 0 1 1 1 1 Transmembrane Fragile-X-F protein GDA1_CD39 PF01150.17 KFQ90770.1 - 4.8e-110 368.1 0.0 5.8e-110 367.8 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Hanta_G2 PF01561.16 KFQ90770.1 - 0.078 11.6 0.4 0.12 10.9 0.4 1.2 1 0 0 1 1 1 0 Hantavirus glycoprotein G2 GDA1_CD39 PF01150.17 KFQ90771.1 - 4.8e-112 374.7 0.0 5.8e-112 374.4 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family TPR_2 PF07719.17 KFQ90772.1 - 9.4e-06 25.4 0.1 0.063 13.4 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ90772.1 - 7.6e-05 22.4 0.0 0.003 17.3 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ90772.1 - 0.0039 17.5 0.7 1.4 9.2 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFQ90772.1 - 0.01 16.0 1.8 0.48 10.6 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ90772.1 - 0.086 12.7 0.7 0.83 9.6 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DNA_pol_A_exo1 PF01612.20 KFQ90773.1 - 2.1e-22 79.7 0.0 1e-21 77.4 0.0 2.0 2 0 0 2 2 2 1 3'-5' exonuclease Mut7-C PF01927.16 KFQ90773.1 - 1.8e-13 50.8 1.0 3.5e-13 49.9 0.2 1.9 2 0 0 2 2 2 1 Mut7-C RNAse domain Kunitz_BPTI PF00014.23 KFQ90774.1 - 1.4e-35 121.2 21.1 7.3e-18 64.6 6.8 2.6 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Lipocalin PF00061.23 KFQ90774.1 - 2.8e-27 95.7 0.0 3.7e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family SL4P PF17618.2 KFQ90774.1 - 0.19 11.8 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein Megourin PF17560.2 KFQ90774.1 - 0.52 10.6 9.4 0.97 9.7 3.1 2.6 2 0 0 2 2 2 0 Aphid Megourins DHR-2 PF06920.13 KFQ90775.1 - 9e-133 443.7 6.2 9e-133 443.7 6.2 2.5 3 0 0 3 3 3 1 Dock homology region 2 DOCK-C2 PF14429.6 KFQ90775.1 - 2.4e-56 190.7 0.0 5.5e-56 189.5 0.0 1.7 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DOCK_N PF16172.5 KFQ90775.1 - 1.5e-39 136.0 0.0 2.7e-39 135.2 0.0 1.5 1 0 0 1 1 1 1 DOCK N-terminus Armet PF10208.9 KFQ90776.1 - 2.9e-40 137.5 1.7 3.2e-40 137.4 1.7 1.0 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding CheZ PF04344.13 KFQ90776.1 - 0.011 15.6 0.0 0.012 15.6 0.0 1.0 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Hamartin PF04388.12 KFQ90776.1 - 0.019 13.7 0.0 0.019 13.7 0.0 1.1 1 0 0 1 1 1 0 Hamartin protein SPOC PF07744.13 KFQ90777.1 - 4.2e-36 124.1 0.0 6.1e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 SPOC domain RRM_1 PF00076.22 KFQ90777.1 - 1.2e-25 89.1 0.0 2e-14 53.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFQ90777.1 - 0.00025 21.0 0.0 0.0012 18.9 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 KFQ90777.1 - 0.0013 18.7 0.0 0.0074 16.3 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KFQ90777.1 - 0.034 14.3 0.0 3.3 7.9 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif Nab6_mRNP_bdg PF10567.9 KFQ90777.1 - 0.31 10.5 1.2 3.3 7.1 0.0 2.2 2 0 0 2 2 2 0 RNA-recognition motif SOBP PF15279.6 KFQ90777.1 - 0.89 10.1 7.0 1.3 9.5 7.0 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Asp-B-Hydro_N PF05279.11 KFQ90777.1 - 3.3 7.7 8.4 5 7.1 8.4 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region LisH PF08513.11 KFQ90778.1 - 0.017 15.1 0.1 0.2 11.7 0.0 2.7 3 0 0 3 3 3 0 LisH ANAPC4_WD40 PF12894.7 KFQ90778.1 - 0.066 13.5 0.0 0.25 11.7 0.0 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain DUF913 PF06025.12 KFQ90778.1 - 7.7 5.4 8.4 20 4.0 0.0 2.7 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) SNF2_N PF00176.23 KFQ90779.1 - 8.1e-50 169.5 0.0 1.5e-49 168.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFQ90779.1 - 5e-15 55.8 0.0 1.3e-14 54.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFQ90779.1 - 7.3e-08 32.6 0.0 3e-07 30.6 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFQ90779.1 - 0.00025 20.3 0.0 0.59 9.3 0.0 2.7 2 0 0 2 2 2 2 ERCC3/RAD25/XPB C-terminal helicase CdiA_C PF18451.1 KFQ90779.1 - 0.0037 17.5 0.0 0.014 15.6 0.0 2.0 1 0 0 1 1 1 1 Contact-dependent growth inhibition CdiA C-terminal domain PI3K_1B_p101 PF10486.9 KFQ90779.1 - 6.7 4.3 10.4 11 3.6 10.4 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Sema PF01403.19 KFQ90780.1 - 4.7e-122 407.8 0.0 2.4e-69 234.2 0.0 2.1 2 0 0 2 2 2 2 Sema domain ig PF00047.25 KFQ90780.1 - 6.5e-06 26.2 0.0 1.3e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFQ90780.1 - 1.4e-05 25.6 0.0 3.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ90780.1 - 0.00023 21.2 0.0 0.00039 20.4 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain PSI PF01437.25 KFQ90780.1 - 0.0025 18.3 9.7 0.0069 16.9 9.7 1.8 1 0 0 1 1 1 1 Plexin repeat V-set PF07686.17 KFQ90780.1 - 0.0046 17.1 0.1 0.029 14.5 0.1 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain OCRE PF17780.1 KFQ90781.1 - 7.1e-22 77.2 2.8 1.5e-21 76.1 2.8 1.6 1 0 0 1 1 1 1 OCRE domain G-patch PF01585.23 KFQ90781.1 - 2.1e-09 37.1 2.6 4.7e-09 36.0 2.6 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFQ90781.1 - 0.0053 16.8 3.2 0.023 14.8 3.2 2.2 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 KFQ90781.1 - 0.13 12.6 0.3 0.36 11.2 0.3 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Mon1 PF03164.14 KFQ90782.1 - 5.5e-144 480.2 0.1 6.4e-144 480.0 0.1 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 T3SSipB PF16535.5 KFQ90783.1 - 0.0026 18.3 0.3 0.0026 18.3 0.3 2.9 2 1 1 3 3 3 1 Type III cell invasion protein SipB Filament PF00038.21 KFQ90783.1 - 0.0091 15.6 24.5 0.015 14.9 24.5 1.3 1 0 0 1 1 1 1 Intermediate filament protein GAS PF13851.6 KFQ90783.1 - 0.033 13.5 37.1 0.13 11.6 13.5 2.7 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding APG17 PF04108.12 KFQ90783.1 - 0.13 11.3 18.6 0.36 9.9 6.4 2.4 1 1 1 2 2 2 0 Autophagy protein Apg17 HIP1_clath_bdg PF16515.5 KFQ90783.1 - 0.15 12.7 33.2 0.13 12.8 7.4 3.5 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 KFQ90783.1 - 0.22 10.3 34.7 0.059 12.3 14.0 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein WEMBL PF05701.11 KFQ90783.1 - 0.34 9.6 29.5 2.8 6.5 22.9 2.5 1 1 1 2 2 2 0 Weak chloroplast movement under blue light MAD PF05557.13 KFQ90783.1 - 0.35 9.2 31.9 0.06 11.7 25.6 1.8 1 1 1 2 2 2 0 Mitotic checkpoint protein HMMR_N PF15905.5 KFQ90783.1 - 0.44 10.0 39.1 1.5 8.2 14.5 2.8 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF812 PF05667.11 KFQ90783.1 - 0.58 9.0 27.9 1 8.2 27.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Laminin_II PF06009.12 KFQ90783.1 - 0.65 10.0 21.4 0.071 13.1 7.0 2.7 2 1 0 2 2 2 0 Laminin Domain II DASH_Duo1 PF08651.10 KFQ90783.1 - 0.65 9.8 8.3 1.3 8.9 2.2 3.5 2 1 1 3 3 3 0 DASH complex subunit Duo1 Cast PF10174.9 KFQ90783.1 - 0.73 8.0 33.0 1.2 7.3 23.7 2.1 1 1 1 2 2 2 0 RIM-binding protein of the cytomatrix active zone ATG16 PF08614.11 KFQ90783.1 - 0.82 9.9 31.0 4.1 7.6 23.3 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 KFQ90783.1 - 0.94 9.5 21.9 0.58 10.2 7.7 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 KFQ90783.1 - 1.2 8.3 21.2 0.18 11.0 7.7 2.3 2 0 0 2 2 2 0 TMPIT-like protein Tropomyosin_1 PF12718.7 KFQ90783.1 - 1.3 9.2 31.2 0.21 11.7 11.0 2.8 2 1 1 3 3 3 0 Tropomyosin like Jnk-SapK_ap_N PF09744.9 KFQ90783.1 - 1.5 9.0 34.1 3.9 7.7 12.2 3.0 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 PI3K_P85_iSH2 PF16454.5 KFQ90783.1 - 1.5 8.4 28.2 96 2.5 28.2 2.2 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Fez1 PF06818.15 KFQ90783.1 - 2.8 8.3 30.4 9 6.7 10.1 2.3 1 1 1 2 2 2 0 Fez1 DUF1759 PF03564.15 KFQ90783.1 - 4.2 7.3 9.8 6.4 6.7 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) Fib_alpha PF08702.10 KFQ90783.1 - 4.5 7.4 23.6 0.97 9.6 10.5 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family MscS_porin PF12795.7 KFQ90783.1 - 4.8 6.7 25.9 0.76 9.3 6.9 2.2 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain IFT57 PF10498.9 KFQ90783.1 - 5 6.0 26.8 0.21 10.5 10.3 2.3 1 1 0 2 2 2 0 Intra-flagellar transport protein 57 Colicin PF01024.19 KFQ90783.1 - 5.4 6.9 10.6 0.6 10.0 5.0 2.0 2 0 0 2 2 2 0 Colicin pore forming domain KASH_CCD PF14662.6 KFQ90783.1 - 5.7 6.7 37.9 6.2 6.6 8.3 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 KFQ90783.1 - 6.2 6.9 38.6 56 3.7 11.9 3.2 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DegS PF05384.11 KFQ90783.1 - 6.9 6.1 27.5 6 6.3 5.9 3.1 1 1 2 3 3 3 0 Sensor protein DegS MCPsignal PF00015.21 KFQ90783.1 - 7.3 6.4 8.7 0.68 9.7 1.8 2.4 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CALCOCO1 PF07888.11 KFQ90783.1 - 8.4 5.1 32.8 16 4.2 32.8 1.4 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like FmiP_Thoc5 PF09766.9 KFQ90783.1 - 9.5 5.4 24.0 0.13 11.5 7.7 2.3 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 Flagellin_N PF00669.20 KFQ90783.1 - 9.6 6.3 9.7 3.3 7.8 1.9 2.7 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region zf-piccolo PF05715.13 KFQ90784.1 - 1.1e-56 188.8 35.5 2e-29 101.5 13.6 2.6 2 0 0 2 2 2 2 Piccolo Zn-finger FYVE_2 PF02318.16 KFQ90784.1 - 4.5e-05 23.6 16.2 0.00034 20.8 3.5 5.0 5 0 0 5 5 5 2 FYVE-type zinc finger IBR PF01485.21 KFQ90784.1 - 0.87 9.9 17.5 1.3 9.3 5.4 2.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Peptidase_S9 PF00326.21 KFQ90785.1 - 2.7e-26 92.4 0.0 4e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KFQ90785.1 - 7.6e-12 45.0 0.0 4.4e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFQ90785.1 - 1.1e-10 41.6 0.0 2e-09 37.5 0.1 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 KFQ90785.1 - 1.7e-05 24.5 0.0 4.3e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KFQ90785.1 - 9.6e-05 22.1 0.0 0.44 10.1 0.0 2.3 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 KFQ90785.1 - 0.0035 17.0 0.0 0.0072 16.0 0.0 1.5 1 0 0 1 1 1 1 Putative esterase BAAT_C PF08840.11 KFQ90785.1 - 0.12 12.3 0.0 0.32 10.9 0.0 1.6 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 KFQ90785.1 - 0.18 11.4 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) AXE1 PF05448.12 KFQ90785.1 - 0.19 10.4 0.0 2 7.0 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) E1_UFD PF09358.10 KFQ90787.1 - 1e-07 32.5 0.0 1.3e-07 32.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin fold domain UMP1 PF05348.11 KFQ90787.1 - 0.045 14.0 0.1 0.049 13.9 0.1 1.2 1 0 0 1 1 1 0 Proteasome maturation factor UMP1 EF-hand_like PF09279.11 KFQ90787.1 - 0.047 14.2 0.1 0.087 13.3 0.1 1.5 1 1 1 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like sCache_like PF16736.5 KFQ90787.1 - 0.052 13.6 0.0 0.06 13.4 0.0 1.1 1 0 0 1 1 1 0 Single Cache-like PID_2 PF14719.6 KFQ90787.1 - 0.13 12.1 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) Phage_P2_GpE PF06528.12 KFQ90787.1 - 0.21 11.2 0.0 0.21 11.2 0.0 1.6 2 0 0 2 2 2 0 Phage P2 GpE IPK PF03770.16 KFQ90788.1 - 1e-64 218.0 0.0 1.5e-64 217.5 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase NTP_transferase PF00483.23 KFQ90789.1 - 5e-28 98.3 0.0 9.6e-28 97.4 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 KFQ90789.1 - 1.3e-09 37.3 10.7 2.9e-09 36.3 4.4 3.2 2 1 0 2 2 2 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFQ90789.1 - 2.5e-05 23.9 3.2 2.5e-05 23.9 3.2 2.9 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KFQ90789.1 - 0.0061 14.8 0.4 0.0085 14.3 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) SPRY PF00622.28 KFQ90790.1 - 8.3e-27 93.7 0.1 1.8e-26 92.6 0.1 1.6 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.6 KFQ90790.1 - 1.1e-08 34.8 8.3 1.1e-08 34.8 8.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ90790.1 - 0.0012 19.1 11.7 0.0032 17.8 11.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFQ90790.1 - 0.017 15.0 14.0 0.047 13.6 14.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFQ90790.1 - 0.02 14.7 12.2 0.061 13.2 12.2 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFQ90790.1 - 0.029 14.3 9.9 0.085 12.8 9.9 1.9 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KFQ90790.1 - 0.14 12.1 14.3 0.048 13.5 9.8 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KFQ90790.1 - 2.2 8.5 8.1 0.96 9.6 5.3 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 KFQ90790.1 - 4.9 7.3 12.0 11 6.1 12.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFQ90790.1 - 7.1 6.9 10.7 20 5.5 10.7 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Caudal_act PF04731.12 KFQ90791.1 - 6.1e-44 149.7 7.0 7.8e-44 149.3 7.0 1.1 1 0 0 1 1 1 1 Caudal like protein activation region Homeodomain PF00046.29 KFQ90791.1 - 8.7e-22 76.7 3.2 1.5e-21 76.0 3.2 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ90791.1 - 0.0045 16.9 0.3 0.0045 16.9 0.3 1.8 2 0 0 2 2 2 1 Homeobox KN domain YdaS_antitoxin PF15943.5 KFQ90791.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Erf4 PF10256.9 KFQ90792.1 - 2.2e-10 40.7 0.0 2.8e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family PDZ PF00595.24 KFQ90793.1 - 9e-62 205.4 3.3 3.3e-16 59.4 0.1 4.2 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 KFQ90793.1 - 1.6e-33 114.3 1.3 6.5e-08 32.3 0.1 4.4 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 KFQ90793.1 - 6.9e-18 64.7 0.5 0.0068 16.7 0.0 4.4 4 0 0 4 4 4 4 PDZ domain zf-RING_UBOX PF13445.6 KFQ90793.1 - 2.7e-06 27.3 9.5 6.7e-06 26.0 9.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFQ90793.1 - 4.1e-05 23.3 9.4 0.00011 22.0 9.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFQ90793.1 - 5e-05 23.4 7.0 0.00016 21.7 7.0 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KFQ90793.1 - 0.00018 21.3 9.9 0.00018 21.3 9.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Tricorn_PDZ PF14685.6 KFQ90793.1 - 0.00039 20.3 0.2 21 5.2 0.0 4.2 4 0 0 4 4 4 0 Tricorn protease PDZ domain zf-RING_2 PF13639.6 KFQ90793.1 - 0.0018 18.6 7.4 0.0018 18.6 7.4 2.1 1 1 1 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KFQ90793.1 - 0.0066 16.4 8.7 0.0066 16.4 8.7 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFQ90793.1 - 0.0097 15.8 6.6 0.029 14.2 6.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ras PF00071.22 KFQ90794.1 - 3.9e-23 81.8 0.0 1.6e-22 79.8 0.0 1.8 1 1 0 1 1 1 1 Ras family Arf PF00025.21 KFQ90794.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family UCH PF00443.29 KFQ90795.1 - 1.9e-59 201.3 2.6 2.2e-59 201.0 2.6 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFQ90795.1 - 6.8e-31 108.0 3.9 9e-31 107.6 3.9 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KFQ90795.1 - 0.00017 21.2 11.1 0.0016 18.0 8.8 2.4 2 1 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase NapB PF03892.14 KFQ90795.1 - 0.14 12.1 2.4 0.36 10.8 2.4 1.7 1 0 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) CEBP_ZZ PF16366.5 KFQ90795.1 - 1.3 9.3 6.9 0.56 10.5 1.3 2.4 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain WH2 PF02205.20 KFQ90796.1 - 4.8e-08 32.6 0.0 9.5e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 WH2 motif MFS_1 PF07690.16 KFQ90797.1 - 2.6e-26 92.4 45.5 7.7e-18 64.5 26.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFQ90797.1 - 0.0046 15.6 20.4 0.084 11.4 5.8 3.4 1 1 2 3 3 3 3 MFS/sugar transport protein zf-RING_2 PF13639.6 KFQ90798.1 - 3.5e-13 49.7 8.0 5.5e-13 49.0 8.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFQ90798.1 - 3.5e-10 40.0 4.8 7e-10 39.0 4.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KFQ90798.1 - 1.6e-08 34.1 3.4 1.6e-08 34.1 3.4 1.7 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFQ90798.1 - 4.7e-08 32.7 6.2 7.4e-08 32.1 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ90798.1 - 1.9e-06 27.6 7.6 3.1e-06 26.9 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFQ90798.1 - 4.3e-05 23.4 6.3 6.8e-05 22.8 6.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KFQ90798.1 - 4.5e-05 23.4 1.4 9.5e-05 22.4 1.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KFQ90798.1 - 0.00056 19.7 4.7 0.00095 19.0 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFQ90798.1 - 0.0017 18.2 4.5 0.003 17.4 4.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFQ90798.1 - 0.0048 16.9 4.0 0.01 15.8 4.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KFQ90798.1 - 0.14 11.8 5.1 0.23 11.1 5.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-HC5HC2H_2 PF13832.6 KFQ90798.1 - 0.16 12.2 1.2 0.3 11.3 1.2 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_4 PF14570.6 KFQ90798.1 - 0.17 11.7 4.5 0.32 10.8 4.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KFQ90798.1 - 0.24 11.7 6.2 0.4 11.0 6.2 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 KFQ90798.1 - 1.1 9.4 7.4 2.3 8.4 7.4 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KFQ90798.1 - 1.9 8.7 5.0 6.8 6.9 5.0 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain GREB1 PF15782.5 KFQ90798.1 - 4.5 4.3 11.6 6.1 3.8 11.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer UPRTase PF14681.6 KFQ90799.1 - 2.6e-30 105.4 0.0 3.8e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KFQ90799.1 - 6e-05 22.6 0.0 6.6e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF4683 PF15735.5 KFQ90800.1 - 8.8e-125 417.5 7.8 8.8e-125 417.5 7.8 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF4683) ABC_membrane PF00664.23 KFQ90802.1 - 1.1e-36 126.9 10.0 1.5e-36 126.5 10.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFQ90802.1 - 2.2e-33 115.7 0.0 4.4e-33 114.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFQ90802.1 - 3.1e-05 23.5 0.5 0.011 15.2 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFQ90802.1 - 0.00089 19.7 0.0 0.0022 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.17 KFQ90802.1 - 0.0081 16.3 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_28 PF13521.6 KFQ90802.1 - 0.0095 16.2 0.0 0.14 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFQ90802.1 - 0.011 15.5 0.2 0.011 15.5 0.2 1.9 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KFQ90802.1 - 0.041 14.1 0.1 0.17 12.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFQ90802.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KFQ90802.1 - 0.075 12.2 0.1 0.23 10.5 0.0 1.7 2 0 0 2 2 2 0 G-protein alpha subunit ATP-synt_ab PF00006.25 KFQ90802.1 - 0.088 12.4 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.6 KFQ90802.1 - 0.12 12.9 0.5 0.86 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KFQ90802.1 - 0.13 12.3 0.0 0.44 10.6 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_7 PF12775.7 KFQ90802.1 - 0.13 11.7 0.0 0.65 9.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 KFQ90802.1 - 0.17 11.6 0.0 0.65 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KFQ90802.1 - 0.2 12.2 0.4 0.85 10.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain DHHC PF01529.20 KFQ90803.1 - 4.2e-24 85.2 16.7 4.8e-24 85.0 16.7 1.0 1 0 0 1 1 1 1 DHHC palmitoyltransferase UPRTase PF14681.6 KFQ90804.1 - 9.5e-50 168.9 0.0 1.1e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KFQ90804.1 - 0.00015 21.3 0.0 0.0002 20.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FGF PF00167.18 KFQ90805.1 - 4.8e-34 117.2 0.1 5.4e-34 117.0 0.1 1.0 1 0 0 1 1 1 1 Fibroblast growth factor MecA PF05389.12 KFQ90805.1 - 0.18 11.4 0.1 0.21 11.2 0.1 1.1 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) OST3_OST6 PF04756.13 KFQ90806.1 - 7.3e-107 357.1 0.0 8.2e-107 356.9 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 KFQ90806.1 - 3.8e-05 23.6 0.0 5.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF4131 PF13567.6 KFQ90806.1 - 0.35 10.5 2.9 0.39 10.4 0.4 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) TctB PF07331.11 KFQ90806.1 - 5.2 7.3 7.1 39 4.5 7.1 2.1 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family COX7B PF05392.11 KFQ90807.1 - 1.4e-34 117.6 0.1 1.6e-34 117.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase chain VIIB HMA PF00403.26 KFQ90808.1 - 9.2e-85 279.0 17.9 3.2e-12 46.7 0.0 7.6 7 0 0 7 7 7 7 Heavy-metal-associated domain Hydrolase PF00702.26 KFQ90808.1 - 4.9e-62 209.9 0.5 9.8e-62 209.0 0.5 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFQ90808.1 - 8.3e-30 103.7 14.5 1.5e-20 73.5 1.3 2.9 2 1 1 3 3 3 2 E1-E2 ATPase Hydrolase_3 PF08282.12 KFQ90808.1 - 4.6e-06 26.6 1.6 0.00061 19.6 0.8 2.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RRM_3 PF08777.11 KFQ90808.1 - 9.2e-05 22.4 0.1 22 5.2 0.0 5.5 6 0 0 6 6 6 0 RNA binding motif Hydrolase_6 PF13344.6 KFQ90808.1 - 0.0063 16.6 0.2 0.041 14.0 0.1 2.6 2 0 0 2 2 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFQ90808.1 - 0.017 15.2 0.0 0.047 13.8 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase CT_C_D PF02682.16 KFQ90808.1 - 0.03 14.1 0.1 24 4.6 0.0 3.5 4 0 0 4 4 4 0 Carboxyltransferase domain, subdomain C and D Spore_YhcN_YlaJ PF09580.10 KFQ90808.1 - 0.14 12.2 1.1 22 5.1 0.1 3.0 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) RRM_occluded PF16842.5 KFQ90808.1 - 0.47 10.3 4.3 0.61 10.0 0.2 3.3 4 0 0 4 4 4 0 Occluded RNA-recognition motif DUF2997 PF11211.8 KFQ90808.1 - 2.2 8.1 16.4 0.96 9.3 0.2 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF2997) PGK PF00162.19 KFQ90809.1 - 1.9e-142 474.7 1.1 2.2e-142 474.5 1.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Angiomotin_C PF12240.8 KFQ90810.1 - 2e-92 308.4 21.3 2e-92 308.4 21.3 3.5 2 1 1 3 3 3 2 Angiomotin C terminal NPV_P10 PF05531.12 KFQ90810.1 - 1.8 9.1 7.2 12 6.4 1.7 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Ion_trans PF00520.31 KFQ90811.1 - 5.4e-33 114.2 13.2 8.3e-33 113.6 13.2 1.2 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.11 KFQ90811.1 - 8.7e-29 99.5 0.3 1.9e-28 98.5 0.3 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.7 KFQ90811.1 - 1.4e-10 41.6 1.1 4e-06 27.3 0.5 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ90811.1 - 1.4e-07 31.9 0.0 0.022 15.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ90811.1 - 3.7e-06 26.9 3.3 0.24 12.1 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat PKD_channel PF08016.12 KFQ90811.1 - 0.00012 20.9 14.0 0.01 14.5 2.5 2.7 2 1 0 2 2 2 2 Polycystin cation channel Ank PF00023.30 KFQ90811.1 - 0.00019 21.7 1.8 0.099 13.1 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KFQ90811.1 - 0.00043 20.5 0.4 1.1 9.7 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Gp-FAR-1 PF05823.12 KFQ90811.1 - 0.066 13.6 11.8 1.1 9.7 1.1 3.4 3 0 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF4423 PF14394.6 KFQ90811.1 - 0.16 11.7 1.2 2.3 7.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) Glyco_tran_28_C PF04101.16 KFQ90812.1 - 2.2e-20 73.3 0.0 2.4e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DCX PF03607.17 KFQ90813.1 - 2.6e-43 145.9 0.1 4.3e-22 78.0 0.0 2.4 2 0 0 2 2 2 2 Doublecortin MGC-24 PF05283.11 KFQ90813.1 - 0.084 13.3 4.7 0.1 13.1 1.2 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF2457 PF10446.9 KFQ90813.1 - 1 8.4 9.9 0.064 12.4 4.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Peptidase_C2 PF00648.21 KFQ90814.1 - 5.8e-119 396.5 0.3 8.7e-119 395.9 0.3 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KFQ90814.1 - 9.8e-33 113.4 0.0 1.7e-32 112.6 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III C2 PF00168.30 KFQ90814.1 - 8.2e-11 42.1 0.1 2.3e-10 40.7 0.0 1.7 2 0 0 2 2 2 1 C2 domain Pkinase PF00069.25 KFQ90815.1 - 1e-72 244.7 0.0 1.4e-72 244.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ90815.1 - 1.6e-45 155.5 0.0 2.4e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KFQ90815.1 - 1.1e-23 83.3 0.0 3.2e-23 81.8 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KFQ90815.1 - 1.5e-07 31.1 0.2 0.00033 20.1 0.0 2.7 2 1 1 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 KFQ90815.1 - 1.8e-06 27.0 1.1 5.4e-06 25.4 1.1 1.9 1 1 0 1 1 1 1 Fungal protein kinase Spt5_N PF11942.8 KFQ90815.1 - 0.00093 20.1 2.3 0.0021 19.0 2.3 1.6 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal APH PF01636.23 KFQ90815.1 - 0.0055 16.7 0.0 0.067 13.1 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family DSHCT PF08148.12 KFQ90815.1 - 0.014 15.1 0.0 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 DSHCT (NUC185) domain Kdo PF06293.14 KFQ90815.1 - 0.056 12.8 0.0 0.13 11.6 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SOG2 PF10428.9 KFQ90815.1 - 1.9 7.6 6.6 3.1 6.9 6.6 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Ribosomal_60s PF00428.19 KFQ90815.1 - 6.4 7.4 9.2 0.49 11.0 0.3 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein VWC PF00093.18 KFQ90816.1 - 6.7e-27 93.6 59.4 2.2e-09 37.5 10.4 3.7 4 0 0 4 4 4 3 von Willebrand factor type C domain Amnionless PF14828.6 KFQ90816.1 - 0.00024 20.1 5.9 0.00024 20.1 5.9 3.2 1 1 2 3 3 3 3 Amnionless DUF1496 PF07383.12 KFQ90816.1 - 0.0084 15.7 2.2 2 8.0 0.0 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1496) AMMECR1 PF01871.17 KFQ90817.1 - 6.6e-47 159.2 0.0 7.7e-47 159.0 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 TMEM164 PF14808.6 KFQ90818.1 - 5.1e-118 393.0 9.4 5.9e-118 392.8 9.4 1.0 1 0 0 1 1 1 1 TMEM164 family DUF1184 PF06683.11 KFQ90818.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) AMP-binding PF00501.28 KFQ90819.1 - 3.7e-109 365.1 0.0 4.9e-109 364.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFQ90819.1 - 1.3e-06 29.3 0.0 3.8e-05 24.6 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NTF2 PF02136.20 KFQ90820.1 - 1e-30 106.8 0.5 1.2e-30 106.6 0.5 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_2 PF12680.7 KFQ90820.1 - 0.042 14.5 0.0 0.05 14.2 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain ODR4-like PF14778.6 KFQ90820.1 - 0.12 11.3 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Olfactory receptor 4-like IRS PF02174.17 KFQ90821.1 - 4.4e-32 109.9 0.0 9.1e-32 108.9 0.0 1.6 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.29 KFQ90821.1 - 1.8e-10 41.2 0.1 7.2e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KFQ90821.1 - 1.6e-05 25.2 0.1 5e-05 23.7 0.1 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.10 KFQ90821.1 - 0.011 16.0 0.0 0.041 14.2 0.0 1.9 2 0 0 2 2 2 0 Plant pleckstrin homology-like region PH_8 PF15409.6 KFQ90821.1 - 0.47 10.8 2.7 32 4.9 1.9 2.9 2 1 0 2 2 2 0 Pleckstrin homology domain PH_13 PF16652.5 KFQ90821.1 - 1.2 9.0 3.3 0.85 9.4 0.1 2.2 3 0 0 3 3 3 0 Pleckstrin homology domain C4 PF01413.19 KFQ90822.1 - 2.7e-67 224.1 6.8 3.1e-46 156.3 0.7 2.0 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Peptidase_C54 PF03416.19 KFQ90824.1 - 1.9e-102 342.4 0.0 2.3e-102 342.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Ank_5 PF13857.6 KFQ90825.1 - 2e-47 158.6 9.8 8.6e-12 45.1 0.1 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFQ90825.1 - 1.2e-46 157.1 2.2 9e-17 61.4 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ90825.1 - 1.8e-46 155.9 5.4 1.7e-12 47.5 0.0 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KFQ90825.1 - 1e-40 136.4 6.5 3e-08 33.7 0.1 5.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 KFQ90825.1 - 3e-39 128.5 2.1 1.2e-07 31.5 0.0 5.2 5 0 0 5 5 5 5 Ankyrin repeat MafB19-deam PF14437.6 KFQ90825.1 - 0.1 12.3 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 MafB19-like deaminase DUF249 PF03158.13 KFQ90825.1 - 0.17 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Multigene family 530 protein V-set PF07686.17 KFQ90826.1 - 6e-22 77.9 3.8 2.2e-20 72.8 0.2 3.0 2 1 1 3 3 3 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFQ90826.1 - 3.3e-20 72.5 5.3 2.5e-09 37.6 0.1 3.0 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFQ90826.1 - 2.1e-14 53.3 0.0 8.8e-07 28.9 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFQ90826.1 - 4.8e-12 45.9 0.9 1.6e-07 31.4 0.1 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFQ90826.1 - 1.5e-09 38.0 4.5 0.00085 19.6 0.1 3.0 2 1 0 2 2 2 2 Immunoglobulin domain V-set_CD47 PF08204.11 KFQ90826.1 - 0.0023 17.9 0.9 0.0062 16.5 0.1 2.0 2 0 0 2 2 2 1 CD47 immunoglobulin-like domain Izumo-Ig PF16706.5 KFQ90826.1 - 0.0062 16.6 0.0 4.7 7.3 0.0 2.5 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Shisa PF13908.6 KFQ90826.1 - 0.025 14.8 0.7 0.039 14.2 0.1 1.6 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Herpes_gE PF02480.16 KFQ90826.1 - 0.038 12.7 0.1 0.7 8.6 0.0 2.0 1 1 0 2 2 2 0 Alphaherpesvirus glycoprotein E Syndecan PF01034.20 KFQ90826.1 - 0.044 13.7 3.6 2.4 8.1 4.6 3.3 3 1 0 3 3 3 0 Syndecan domain TMEM154 PF15102.6 KFQ90826.1 - 0.058 13.3 0.1 0.15 11.9 0.0 1.7 1 1 1 2 2 2 0 TMEM154 protein family MscL PF01741.18 KFQ90826.1 - 0.062 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL EphA2_TM PF14575.6 KFQ90826.1 - 0.15 13.0 0.0 0.27 12.1 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Mucin15 PF15672.5 KFQ90826.1 - 1.1 8.6 7.6 0.36 10.3 0.7 2.7 2 1 1 3 3 3 0 Cell-membrane associated Mucin15 C2 PF00168.30 KFQ90827.1 - 2.5e-36 124.1 0.5 1.9e-19 69.8 0.1 2.2 2 0 0 2 2 2 2 C2 domain Ras PF00071.22 KFQ90828.1 - 8e-30 103.6 0.1 9.6e-30 103.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ90828.1 - 6.6e-06 26.3 0.0 1.2e-05 25.5 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase CENP-M PF11111.8 KFQ90828.1 - 0.014 14.6 0.0 0.018 14.3 0.0 1.1 1 0 0 1 1 1 0 Centromere protein M (CENP-M) Prefoldin PF02996.17 KFQ90829.1 - 2.6e-37 127.4 0.3 4e-37 126.8 0.3 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KFQ90829.1 - 0.00036 20.5 4.2 0.063 13.2 0.0 2.3 2 1 0 2 2 2 2 Prefoldin subunit ATG19_autophagy PF12744.7 KFQ90829.1 - 0.056 12.6 1.3 0.084 12.1 1.3 1.2 1 0 0 1 1 1 0 Autophagy protein Atg19, Atg8-binding DUF1664 PF07889.12 KFQ90829.1 - 0.25 11.4 1.7 4.1 7.5 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ANTH PF07651.16 KFQ90830.1 - 1.6e-69 234.0 1.3 2.6e-69 233.3 1.3 1.4 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KFQ90830.1 - 8.4e-07 29.1 0.1 2e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 ENTH domain PH PF00169.29 KFQ90831.1 - 3.2e-20 72.6 0.7 6.3e-20 71.6 0.7 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFQ90831.1 - 8e-05 23.0 4.2 0.00077 19.8 4.2 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 KFQ90831.1 - 0.037 14.4 0.5 0.092 13.1 0.5 1.7 1 1 0 1 1 1 0 Pleckstrin homology domain Mcp5_PH PF12814.7 KFQ90831.1 - 0.085 13.0 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology PH_3 PF14593.6 KFQ90831.1 - 0.54 10.4 3.1 4.2 7.5 3.1 2.2 1 1 0 1 1 1 0 PH domain SNF2_N PF00176.23 KFQ90832.1 - 4.4e-80 269.0 0.4 1e-79 267.8 0.4 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KFQ90832.1 - 2.2e-42 143.7 3.6 2.2e-42 143.7 3.6 2.7 3 0 0 3 3 3 1 SLIDE HAND PF09110.11 KFQ90832.1 - 3e-30 105.2 2.4 3e-30 105.2 2.4 3.5 3 0 0 3 3 3 1 HAND Helicase_C PF00271.31 KFQ90832.1 - 9.8e-22 77.4 0.0 1.2e-20 74.0 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFQ90832.1 - 8.7e-12 45.4 0.1 9.6e-11 42.0 0.0 2.9 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFQ90832.1 - 4.4e-07 29.8 0.0 2.2e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase DBINO PF13892.6 KFQ90832.1 - 2.1e-05 24.9 0.2 2.1e-05 24.9 0.2 5.3 5 0 0 5 5 5 1 DNA-binding domain HDA2-3 PF11496.8 KFQ90832.1 - 2.2e-05 23.8 0.0 6.2e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Myb_DNA-binding PF00249.31 KFQ90832.1 - 2.9e-05 24.1 0.1 0.44 10.8 0.0 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain ERCC3_RAD25_C PF16203.5 KFQ90832.1 - 0.0021 17.3 0.0 0.0069 15.6 0.0 1.9 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase UBA_2 PF08587.11 KFQ90832.1 - 0.14 12.2 1.7 0.8 9.9 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin associated domain (UBA) Tox-GHH PF15636.6 KFQ90833.1 - 2.2e-29 101.2 0.9 4.4e-29 100.3 0.9 1.5 1 0 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin Ten_N PF06484.12 KFQ90833.1 - 7.6e-24 85.3 8.1 1.1e-23 84.7 8.1 1.3 1 0 0 1 1 1 1 Teneurin Intracellular Region EGF_2 PF07974.13 KFQ90833.1 - 1.2e-19 70.3 153.1 0.00037 20.8 9.4 9.7 8 1 1 9 9 9 7 EGF-like domain RHS_repeat PF05593.14 KFQ90833.1 - 5.2e-12 46.0 30.1 0.00052 20.5 1.4 8.7 8 1 1 9 9 9 5 RHS Repeat NHL PF01436.21 KFQ90833.1 - 1.4e-06 28.0 3.0 0.43 10.7 0.0 6.1 5 0 0 5 5 5 1 NHL repeat SGL PF08450.12 KFQ90833.1 - 0.0024 17.5 0.2 0.55 9.8 0.0 3.5 3 1 1 4 4 4 1 SMP-30/Gluconolactonase/LRE-like region CarboxypepD_reg PF13620.6 KFQ90833.1 - 0.0079 16.4 0.2 0.026 14.8 0.2 1.9 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF1939 PF09154.10 KFQ90833.1 - 0.059 13.5 0.2 0.21 11.8 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) Imm27 PF15590.6 KFQ90833.1 - 0.061 13.1 0.4 0.9 9.4 0.0 3.0 3 0 0 3 3 3 0 Immunity protein 27 RHS PF03527.14 KFQ90833.1 - 0.1 12.4 1.8 0.21 11.3 0.0 2.5 3 0 0 3 3 3 0 RHS protein SH2 PF00017.24 KFQ90834.1 - 2.1e-14 53.4 0.0 2.6e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 SH2 domain STAG PF08514.11 KFQ90835.1 - 2e-37 127.6 0.1 9.1e-37 125.4 0.1 2.2 1 0 0 1 1 1 1 STAG domain Cnd3 PF12719.7 KFQ90835.1 - 0.0049 16.1 0.3 0.025 13.8 0.3 2.2 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain AdoHcyase_NAD PF00670.21 KFQ90835.1 - 0.04 14.0 0.0 0.092 12.8 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 7TMR-HDED PF07697.11 KFQ90835.1 - 0.25 11.4 6.9 1.9 8.6 0.3 3.7 3 1 0 3 3 3 0 7TM-HD extracellular Tho2 PF11262.8 KFQ90836.1 - 3.7e-104 348.1 2.3 3.7e-104 348.1 2.3 4.4 4 2 1 5 5 5 1 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 KFQ90836.1 - 6.4e-83 279.5 5.7 5.8e-57 193.7 2.6 4.8 3 2 1 4 4 4 2 THO complex subunit 2 N-terminus Thoc2 PF11732.8 KFQ90836.1 - 3.6e-37 126.3 0.9 3.1e-36 123.3 0.2 2.8 3 0 0 3 3 3 1 Transcription- and export-related complex subunit ANF_receptor PF01094.28 KFQ90838.1 - 3.5e-61 207.3 1.0 5e-61 206.8 1.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 KFQ90838.1 - 5.5e-59 198.3 0.0 1e-58 197.4 0.0 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFQ90838.1 - 1.1e-45 154.5 0.0 2.3e-45 153.5 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFQ90838.1 - 2.3e-24 86.1 0.0 4.2e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF2061 PF09834.9 KFQ90838.1 - 0.082 13.4 0.2 0.27 11.8 0.2 2.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2061) NusG_add PF18298.1 KFQ90838.1 - 0.089 13.0 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 NusG additional domain Ig_3 PF13927.6 KFQ90840.1 - 7.8e-20 71.3 3.4 9e-11 42.2 0.1 3.6 4 0 0 4 4 4 2 Immunoglobulin domain V-set PF07686.17 KFQ90840.1 - 1.4e-18 67.1 2.7 2.1e-15 56.8 0.0 3.7 3 1 1 4 4 4 2 Immunoglobulin V-set domain ig PF00047.25 KFQ90840.1 - 2.6e-16 59.5 2.6 9.4e-08 32.1 0.1 3.4 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFQ90840.1 - 5.4e-15 55.5 0.4 4.8e-08 33.2 0.1 3.5 3 1 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFQ90840.1 - 4.6e-12 45.8 0.1 1.3e-05 25.1 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_6 PF18452.1 KFQ90840.1 - 0.011 15.3 0.1 6.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain Ig_5 PF16681.5 KFQ90840.1 - 0.027 14.9 0.0 0.82 10.1 0.0 2.8 3 0 0 3 3 3 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain DUF3619 PF12279.8 KFQ90840.1 - 0.036 14.4 0.0 0.078 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) FAM163 PF15069.6 KFQ90840.1 - 0.06 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 FAM163 family EphA2_TM PF14575.6 KFQ90840.1 - 0.068 14.1 0.0 0.12 13.2 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 KFQ90840.1 - 0.074 13.3 0.1 0.22 11.7 0.0 1.7 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Hist_deacetyl PF00850.19 KFQ90842.1 - 8e-86 288.3 0.1 1.1e-85 287.8 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Sulfotransfer_1 PF00685.27 KFQ90843.1 - 1.8e-35 122.7 0.2 2.3e-35 122.4 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFQ90843.1 - 1.8e-10 41.6 0.0 1.2e-05 25.9 0.0 2.1 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFQ90843.1 - 0.004 17.1 0.2 0.0061 16.5 0.2 1.3 1 0 0 1 1 1 1 Sulfotransferase family Pkinase_Tyr PF07714.17 KFQ90844.1 - 5.2e-96 320.9 0.0 6.3e-96 320.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ90844.1 - 1.1e-48 165.9 0.0 1.5e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFQ90844.1 - 1.4e-24 86.0 0.1 3.8e-24 84.6 0.1 1.7 2 0 0 2 2 2 1 SH2 domain Haspin_kinase PF12330.8 KFQ90844.1 - 0.039 12.9 0.0 0.15 11.0 0.0 1.8 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KFQ90844.1 - 0.056 12.8 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFQ90844.1 - 0.14 12.1 0.0 3 7.7 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family 5_nucleotid PF05761.14 KFQ90845.1 - 1.9e-49 168.8 0.1 2.4e-49 168.5 0.1 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.6 KFQ90845.1 - 0.0017 18.4 0.0 0.028 14.5 0.0 2.5 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFQ90845.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Collagen PF01391.18 KFQ90846.1 - 2.2e-69 229.1 286.1 4.4e-08 32.8 27.5 10.3 1 1 6 7 7 7 6 Collagen triple helix repeat (20 copies) C1q PF00386.21 KFQ90846.1 - 7e-39 132.9 0.1 8.9e-39 132.6 0.1 1.1 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 KFQ90846.1 - 0.0024 17.8 0.0 0.0037 17.2 0.0 1.1 1 0 0 1 1 1 1 BclA C-terminal domain DUF4962 PF16332.5 KFQ90847.1 - 7.2e-07 28.1 4.2 7.2e-07 28.1 4.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4962) Hepar_II_III PF07940.13 KFQ90847.1 - 0.052 13.2 0.0 3.9 7.0 0.0 2.4 2 0 0 2 2 2 0 Heparinase II/III-like protein DUF3340 PF11818.8 KFQ90847.1 - 0.45 10.7 5.4 0.84 9.8 5.4 1.3 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) TRAPP PF04051.16 KFQ90848.1 - 7.5e-31 106.8 0.0 8.4e-31 106.7 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ca_hom_mod PF14798.6 KFQ90849.1 - 1.6e-88 296.1 11.9 1.9e-88 295.8 11.9 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator Ca_hom_mod PF14798.6 KFQ90850.1 - 9.2e-85 283.8 2.4 1.1e-84 283.6 2.4 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator Wzy_C PF04932.15 KFQ90850.1 - 0.39 10.3 2.9 2.3 7.8 0.1 2.4 2 1 0 2 2 2 0 O-Antigen ligase DUF2093 PF09866.9 KFQ90850.1 - 0.59 9.6 4.4 23 4.5 0.2 3.7 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2093) SNARE PF05739.19 KFQ90850.1 - 1.3 9.0 4.7 1.8 8.6 0.1 2.5 2 0 0 2 2 2 0 SNARE domain RWD PF05773.22 KFQ90851.1 - 1.2e-16 61.0 0.2 1.2e-16 61.0 0.2 1.9 2 1 0 2 2 2 1 RWD domain DFRP_C PF16543.5 KFQ90851.1 - 1.5e-06 28.6 9.1 1.5e-06 28.6 9.1 2.7 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 ACC_central PF08326.12 KFQ90851.1 - 0.0068 14.7 3.8 0.0088 14.3 3.8 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region DUF445 PF04286.12 KFQ90851.1 - 0.013 15.3 9.9 0.016 15.0 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Folliculin PF11704.8 KFQ90851.1 - 0.048 13.5 1.6 0.075 12.9 1.6 1.4 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport BUD22 PF09073.10 KFQ90851.1 - 0.2 11.0 10.5 0.2 10.9 10.5 1.1 1 0 0 1 1 1 0 BUD22 SeleniumBinding PF11524.8 KFQ90851.1 - 0.2 12.1 1.2 0.42 11.1 0.4 2.1 2 1 0 2 2 2 0 Selenium binding protein A_deaminase_N PF08451.11 KFQ90851.1 - 0.54 10.6 5.5 1.3 9.4 5.5 1.7 1 1 0 1 1 1 0 Adenosine/AMP deaminase N-terminal DHHA1 PF02272.19 KFQ90851.1 - 0.85 10.0 6.4 1.4 9.3 5.7 1.8 1 1 1 2 2 2 0 DHHA1 domain Sulfotransfer_1 PF00685.27 KFQ90852.1 - 2.1e-73 247.1 0.1 2.5e-73 246.8 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFQ90852.1 - 5.5e-08 33.4 0.0 0.00025 21.5 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase family Peptidase_C78 PF07910.13 KFQ90853.1 - 2.2e-72 243.0 0.0 3.4e-72 242.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 KFQ90853.1 - 0.0021 17.5 0.0 0.003 17.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C54 YgbB PF02542.16 KFQ90853.1 - 0.17 12.2 0.0 1.4 9.2 0.0 2.2 2 0 0 2 2 2 0 YgbB family Zn-C2H2_12 PF18112.1 KFQ90853.1 - 0.19 12.2 3.1 1 9.9 3.1 2.2 1 1 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain Arm PF00514.23 KFQ90854.1 - 4e-91 296.6 15.9 7.7e-13 48.0 0.6 8.7 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KFQ90854.1 - 2.3e-27 95.3 1.7 5.5e-27 94.0 1.7 1.7 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.6 KFQ90854.1 - 1e-23 83.5 0.0 5.9e-07 29.8 0.0 5.0 3 1 1 5 5 4 4 HEAT repeats HEAT_EZ PF13513.6 KFQ90854.1 - 6.5e-23 80.8 4.7 2.1e-07 31.3 0.0 6.1 4 2 1 5 5 5 4 HEAT-like repeat Arm_3 PF16186.5 KFQ90854.1 - 1.4e-22 79.0 3.9 4.3e-22 77.4 3.1 2.3 3 0 0 3 3 3 1 Atypical Arm repeat HEAT PF02985.22 KFQ90854.1 - 4.4e-19 66.9 4.7 0.00049 20.1 0.0 8.3 9 0 0 9 9 8 2 HEAT repeat V-ATPase_H_C PF11698.8 KFQ90854.1 - 4.2e-06 26.8 0.0 0.13 12.4 0.0 4.5 3 3 2 5 5 5 2 V-ATPase subunit H RICTOR_V PF14668.6 KFQ90854.1 - 6.1e-06 26.4 1.0 0.19 12.0 0.0 4.6 4 2 1 5 5 4 1 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.13 KFQ90854.1 - 9.9e-05 21.9 0.0 0.24 10.8 0.0 3.0 1 1 2 3 3 3 2 Armadillo-like Adaptin_N PF01602.20 KFQ90854.1 - 0.00016 20.4 0.0 0.0035 16.0 0.0 2.4 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_N PF03224.14 KFQ90854.1 - 0.00032 20.1 0.1 0.28 10.4 0.0 3.7 2 2 0 3 3 3 1 V-ATPase subunit H HEAT_PBS PF03130.16 KFQ90854.1 - 0.007 16.9 2.3 6.5 7.7 0.0 5.0 6 0 0 6 6 4 1 PBS lyase HEAT-like repeat NopRA1 PF16201.5 KFQ90854.1 - 0.0078 15.8 0.0 6.9 6.2 0.0 3.7 1 1 2 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 Atx10homo_assoc PF09759.9 KFQ90854.1 - 0.018 15.1 0.1 0.37 10.8 0.0 2.6 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain UNC45-central PF11701.8 KFQ90854.1 - 0.045 13.7 0.0 0.91 9.5 0.0 2.6 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central CTNNBL PF08216.11 KFQ90854.1 - 0.062 13.5 0.0 14 5.9 0.0 3.7 4 0 0 4 4 4 0 Catenin-beta-like, Arm-motif containing nuclear Big_5 PF13205.6 KFQ90854.1 - 0.15 12.8 0.1 0.27 12.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain SEN1_N PF12726.7 KFQ90854.1 - 0.15 10.2 0.0 12 3.9 0.0 2.7 2 1 1 3 3 3 0 SEN1 N terminal NUSAP PF16006.5 KFQ90854.1 - 0.21 11.3 4.4 0.29 10.8 4.4 1.2 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein DUF1075 PF06388.11 KFQ90855.1 - 5.5e-39 133.0 0.2 7.1e-39 132.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1075) RFX_DNA_binding PF02257.15 KFQ90856.1 - 3.5e-31 107.7 0.1 1.1e-30 106.1 0.1 1.9 1 0 0 1 1 1 1 RFX DNA-binding domain RAG2_PHD PF13341.6 KFQ90856.1 - 0.09 12.8 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 RAG2 PHD domain Pox_D5 PF03288.16 KFQ90856.1 - 0.094 13.2 0.1 0.24 11.9 0.1 1.7 1 0 0 1 1 1 0 Poxvirus D5 protein-like Pkinase_Tyr PF07714.17 KFQ90858.1 - 6.6e-96 320.5 0.0 1.2e-95 319.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase fn3 PF00041.21 KFQ90858.1 - 4.5e-43 145.5 32.1 6.4e-10 39.2 0.5 9.8 9 0 0 9 9 9 5 Fibronectin type III domain Pkinase PF00069.25 KFQ90858.1 - 4.5e-41 140.9 0.0 7.6e-41 140.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF2613 PF11021.8 KFQ90858.1 - 0.14 12.3 0.2 0.43 10.7 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) LapA_dom PF06305.11 KFQ90858.1 - 0.32 10.9 0.9 0.72 9.7 0.9 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain F5_F8_type_C PF00754.25 KFQ90859.1 - 2.5e-27 95.5 2.4 5.5e-27 94.4 2.4 1.6 1 0 0 1 1 1 1 F5/8 type C domain CUB PF00431.20 KFQ90859.1 - 2.8e-17 63.1 0.3 8.1e-17 61.6 0.0 2.0 2 0 0 2 2 2 1 CUB domain LCCL PF03815.19 KFQ90859.1 - 1.5e-14 53.9 0.1 3.6e-14 52.6 0.1 1.6 1 0 0 1 1 1 1 LCCL domain DUF3377 PF11857.8 KFQ90859.1 - 0.12 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) PDZ PF00595.24 KFQ90860.1 - 6e-17 61.8 1.9 6.2e-17 61.7 0.5 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFQ90860.1 - 7.2e-09 35.4 0.1 1.6e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFQ90860.1 - 4.7e-05 23.6 0.1 0.00015 22.0 0.1 2.0 1 0 0 1 1 1 1 PDZ domain DUF903 PF06004.12 KFQ90860.1 - 0.016 15.1 0.1 0.034 14.0 0.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) bZIP_2 PF07716.15 KFQ90860.1 - 0.018 15.1 7.7 0.018 15.1 7.7 2.7 2 0 0 2 2 2 0 Basic region leucine zipper PRKG1_interact PF15898.5 KFQ90860.1 - 0.53 11.2 11.0 1.5 9.8 11.0 1.7 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DivIC PF04977.15 KFQ90860.1 - 1 9.2 12.3 1 9.1 2.6 2.8 2 0 0 2 2 2 0 Septum formation initiator JAKMIP_CC3 PF16034.5 KFQ90860.1 - 1.7 8.6 10.6 0.076 13.0 2.8 2.2 1 1 1 2 2 2 0 JAKMIP CC3 domain Atg14 PF10186.9 KFQ90860.1 - 4.3 6.3 9.3 6 5.9 9.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LRR_8 PF13855.6 KFQ90861.1 - 4.6e-56 186.4 51.0 8.6e-14 51.1 0.8 7.6 5 2 2 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 KFQ90861.1 - 2.6e-33 113.5 52.4 5.4e-06 26.7 0.9 10.1 2 2 10 13 13 13 12 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFQ90861.1 - 8e-14 51.5 27.2 1.8e-05 24.3 1.6 6.1 1 1 6 7 7 7 5 Leucine-rich repeat LRR_1 PF00560.33 KFQ90861.1 - 3.1e-11 42.2 34.9 0.54 11.0 0.1 14.0 14 1 0 14 14 14 3 Leucine Rich Repeat LRR_5 PF13306.6 KFQ90861.1 - 8.8e-11 41.9 6.5 2e-06 27.8 0.3 4.4 2 2 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KFQ90861.1 - 0.0012 18.7 31.8 0.44 10.7 0.1 10.8 12 0 0 12 12 12 1 Leucine Rich repeat Prenyltransf PF01255.19 KFQ90862.1 - 2e-08 34.1 0.0 2.2e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Methyltransf_11 PF08241.12 KFQ90862.1 - 0.027 15.1 0.1 0.04 14.6 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF5099 PF17025.5 KFQ90862.1 - 0.035 14.5 0.2 0.12 12.8 0.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5099) Methyltransf_25 PF13649.6 KFQ90862.1 - 0.065 13.9 0.1 0.1 13.3 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KFQ90862.1 - 0.12 13.1 0.1 0.2 12.4 0.1 1.4 1 1 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 KFQ90866.1 - 3.1e-65 220.2 0.0 3.1e-65 220.2 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ90866.1 - 2.3e-44 151.6 1.2 4.9e-44 150.6 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFQ90866.1 - 0.022 14.7 3.2 0.027 14.4 0.0 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family TcdB_N PF12918.7 KFQ90866.1 - 4.7 7.6 14.1 2 8.8 5.3 4.0 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain Aldedh PF00171.22 KFQ90867.1 - 1.2e-69 235.1 0.0 5e-69 233.0 0.0 1.7 1 1 0 1 1 1 1 Aldehyde dehydrogenase family LigT_PEase PF02834.16 KFQ90867.1 - 0.085 13.1 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 LigT like Phosphoesterase Fer4_7 PF12838.7 KFQ90868.1 - 1.8e-08 34.8 4.2 3e-08 34.1 4.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 KFQ90868.1 - 1.7e-07 30.8 11.8 5.2e-06 26.0 4.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 KFQ90868.1 - 1.3e-05 25.2 3.7 2.1e-05 24.6 3.7 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 KFQ90868.1 - 2.9e-05 24.1 5.0 3.9e-05 23.7 0.6 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KFQ90868.1 - 7.6e-05 22.7 4.1 0.00015 21.8 4.1 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KFQ90868.1 - 0.00011 22.1 5.3 0.00011 22.1 5.3 2.1 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_16 PF13484.6 KFQ90868.1 - 0.0004 21.2 6.7 0.00071 20.5 6.5 1.7 1 1 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 KFQ90868.1 - 0.00064 20.0 2.7 0.00064 20.0 2.7 1.8 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_2 PF12797.7 KFQ90868.1 - 0.0015 18.5 3.2 0.0015 18.5 3.2 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_17 PF13534.6 KFQ90868.1 - 0.029 14.9 2.7 0.029 14.9 2.7 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 KFQ90868.1 - 0.06 13.6 1.8 0.32 11.3 0.4 2.1 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_8 PF13183.6 KFQ90868.1 - 0.096 13.1 7.3 0.12 12.9 2.7 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 KFQ90868.1 - 0.41 11.2 7.0 0.45 11.1 4.0 2.1 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 KFQ90868.1 - 0.44 10.7 4.4 1.1 9.5 4.4 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain V_ATPase_I PF01496.19 KFQ90869.1 - 4.8e-215 716.1 11.7 8.2e-196 652.5 0.5 2.0 2 0 0 2 2 2 2 V-type ATPase 116kDa subunit family MRVI1 PF05781.12 KFQ90869.1 - 0.63 8.7 1.0 0.89 8.2 1.0 1.1 1 0 0 1 1 1 0 MRVI1 protein 7tm_4 PF13853.6 KFQ90870.1 - 6e-16 59.0 0.3 7.6e-16 58.7 0.3 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ90870.1 - 0.015 14.6 0.6 0.019 14.3 0.6 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFQ90871.1 - 9.2e-58 196.2 17.6 1.1e-57 196.0 17.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ90871.1 - 4.1e-24 85.3 17.2 6.3e-24 84.7 17.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) VGCC_beta4Aa_N PF12052.8 KFQ90871.1 - 0.17 12.0 0.7 0.27 11.4 0.7 1.3 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal 7tm_4 PF13853.6 KFQ90872.1 - 5.8e-51 173.9 21.0 6.8e-51 173.6 21.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ90872.1 - 3.7e-24 85.5 24.2 4.7e-24 85.1 24.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFQ90873.1 - 1.5e-46 159.4 19.4 1.8e-46 159.2 19.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ90873.1 - 1.5e-22 80.2 22.2 1.9e-22 79.8 22.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFQ90873.1 - 0.24 11.0 25.2 0.39 10.3 25.2 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx SLC3A2_N PF16028.5 KFQ90873.1 - 5 6.7 5.0 4 7.1 1.4 2.3 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus 7tm_4 PF13853.6 KFQ90874.1 - 1.6e-41 142.9 22.9 1.9e-41 142.7 22.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ90874.1 - 2.4e-22 79.5 24.6 3.3e-22 79.1 24.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SLC3A2_N PF16028.5 KFQ90874.1 - 0.093 12.3 0.2 0.093 12.3 0.2 2.6 3 0 0 3 3 3 0 Solute carrier family 3 member 2 N-terminus 7tm_4 PF13853.6 KFQ90875.1 - 7.2e-51 173.6 22.2 8.2e-51 173.4 22.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ90875.1 - 4.4e-24 85.2 20.7 5.8e-24 84.8 20.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFQ90876.1 - 3e-55 187.9 14.9 3.5e-55 187.7 14.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ90876.1 - 3e-25 89.1 13.6 4.6e-25 88.4 13.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ90876.1 - 0.00056 19.4 15.2 0.0067 15.8 15.2 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx XPG_N PF00752.17 KFQ90877.1 - 1e-37 128.7 0.0 2.9e-37 127.2 0.0 1.8 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 KFQ90877.1 - 6.9e-31 106.5 0.4 1.7e-30 105.2 0.0 1.9 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 KFQ90877.1 - 7e-08 33.0 0.1 4.7e-07 30.3 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.16 KFQ90877.1 - 0.0037 17.2 0.0 0.015 15.2 0.0 1.9 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain HHH_5 PF14520.6 KFQ90877.1 - 0.016 15.8 0.0 0.043 14.4 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain Ost5 PF05251.12 KFQ90878.1 - 4.2e-18 65.4 0.5 4.5e-18 65.3 0.5 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 Phage_holin_3_3 PF16083.5 KFQ90878.1 - 0.00052 20.1 0.1 0.00054 20.0 0.1 1.0 1 0 0 1 1 1 1 LydA holin phage, holin superfamily III MPS-4 PF17523.2 KFQ90878.1 - 0.16 12.1 1.4 0.17 12.1 1.4 1.1 1 0 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 Lipase_3 PF01764.25 KFQ90879.1 - 5.4e-10 39.3 0.0 1.1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) C2 PF00168.30 KFQ90880.1 - 2.8e-52 175.3 2.8 6.5e-27 93.8 0.1 2.3 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 KFQ90880.1 - 0.0031 17.1 0.1 0.036 13.6 0.0 2.4 2 1 1 3 3 3 1 CEP76 C2 domain SCIMP PF15050.6 KFQ90880.1 - 0.012 16.1 0.0 0.04 14.4 0.0 2.0 1 0 0 1 1 1 0 SCIMP protein LRR_4 PF12799.7 KFQ90881.1 - 2.9e-14 53.0 0.0 0.00067 20.0 0.0 3.1 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFQ90881.1 - 4.2e-11 42.4 0.3 4.5e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 KFQ90881.1 - 0.00019 21.5 5.1 3.5 8.5 0.1 4.5 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_9 PF14580.6 KFQ90881.1 - 0.0042 16.6 0.0 0.021 14.3 0.0 1.8 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 KFQ90881.1 - 0.072 13.2 0.6 7.7 6.8 0.0 2.7 3 0 0 3 3 3 0 Leucine Rich repeat Sdh5 PF03937.16 KFQ90882.1 - 4e-18 65.2 0.7 5.5e-18 64.7 0.7 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase DUF5552 PF17706.1 KFQ90882.1 - 0.18 11.5 0.0 0.18 11.5 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5552) RRM_1 PF00076.22 KFQ90883.1 - 4.7e-06 26.3 0.0 1.1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFQ90883.1 - 0.042 14.0 0.0 0.08 13.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif Transmemb_17 PF09799.9 KFQ90884.1 - 2e-19 70.2 1.4 2.6e-19 69.8 1.4 1.2 1 0 0 1 1 1 1 Predicted membrane protein TMEM138 PF14935.6 KFQ90885.1 - 1.2e-32 113.1 1.4 1.3e-32 112.9 1.4 1.0 1 0 0 1 1 1 1 Transmembrane protein 138 Cytochrom_B561 PF03188.16 KFQ90886.1 - 1.4e-43 148.3 9.0 1.4e-43 148.3 9.0 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Metal_resist PF13801.6 KFQ90886.1 - 0.16 12.1 2.7 7.9 6.7 1.1 2.5 2 0 0 2 2 2 0 Heavy-metal resistance Holin_9 PF16936.5 KFQ90886.1 - 10 6.4 11.7 3 8.1 6.5 2.8 2 1 0 2 2 2 0 Putative holin MMS1_N PF10433.9 KFQ90887.1 - 1.9e-118 396.2 0.0 4.7e-118 394.9 0.0 1.7 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KFQ90887.1 - 1.6e-82 277.4 0.1 1.4e-81 274.3 0.1 2.4 2 0 0 2 2 2 1 CPSF A subunit region cEGF PF12662.7 KFQ90888.1 - 9.9e-15 54.2 35.0 3.6e-06 26.8 0.6 5.7 5 0 0 5 5 5 3 Complement Clr-like EGF-like EGF_CA PF07645.15 KFQ90888.1 - 8.2e-13 48.3 18.5 8.3e-08 32.3 5.7 5.0 3 1 1 4 4 4 2 Calcium-binding EGF domain FXa_inhibition PF14670.6 KFQ90888.1 - 3e-11 43.4 25.6 9.1e-07 29.1 10.2 5.8 3 2 2 5 5 5 2 Coagulation Factor Xa inhibitory site Fibrillin_U_N PF18193.1 KFQ90888.1 - 2.5e-05 24.3 8.1 2.5e-05 24.3 8.1 3.1 3 0 0 3 3 3 1 Fibrillin 1 unique N-terminal domain EGF PF00008.27 KFQ90888.1 - 0.00017 21.8 7.4 0.00017 21.8 7.4 6.1 4 3 0 4 4 4 2 EGF-like domain hEGF PF12661.7 KFQ90888.1 - 0.0064 17.1 15.1 0.012 16.3 4.1 7.2 8 1 0 8 8 8 2 Human growth factor-like EGF Asp PF00026.23 KFQ90889.1 - 4.2e-113 377.9 1.4 4.8e-113 377.7 1.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFQ90889.1 - 8.3e-16 58.7 1.9 2.5e-13 50.7 0.8 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.12 KFQ90889.1 - 3.9e-11 42.6 0.5 6.4e-11 41.9 0.5 1.4 1 0 0 1 1 1 1 A1 Propeptide TAXi_C PF14541.6 KFQ90889.1 - 0.002 17.9 0.0 0.54 10.0 0.0 2.4 1 1 1 2 2 2 2 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KFQ90889.1 - 0.0047 17.5 0.1 2.3 8.9 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease Mod_r PF07200.13 KFQ90890.1 - 1.1e-34 119.7 21.1 1.5e-34 119.2 21.1 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein RNA_pol_Rpb2_3 PF04565.16 KFQ90890.1 - 0.02 15.1 0.0 0.34 11.1 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 3 zf-C4H2 PF10146.9 KFQ90890.1 - 0.039 14.3 5.2 0.05 13.9 5.2 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein Methyltransf_14 PF08484.11 KFQ90890.1 - 0.054 13.3 0.2 0.089 12.6 0.1 1.4 1 1 0 1 1 1 0 C-methyltransferase C-terminal domain DUF2703 PF10865.8 KFQ90890.1 - 1.9 8.7 5.6 0.27 11.4 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) Atg14 PF10186.9 KFQ90890.1 - 6.7 5.7 12.2 8.8 5.3 12.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SRCR PF00530.18 KFQ90891.1 - 9.7e-45 151.2 18.4 1.6e-26 92.7 6.9 2.1 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFQ90891.1 - 9.2e-06 26.1 11.7 0.0047 17.4 0.9 2.9 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFQ90891.1 - 0.084 13.4 6.2 2.1 8.9 0.4 2.5 3 0 0 3 3 3 0 Hepsin, SRCR domain PTR2 PF00854.21 KFQ90892.1 - 2.7e-81 273.4 0.5 3.9e-81 272.9 0.5 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 KFQ90892.1 - 5.9e-05 22.2 17.4 0.00012 21.1 17.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TMEM132 PF16070.5 KFQ90893.1 - 9.8e-63 212.6 0.0 1.3e-62 212.2 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein family 132 TMEM132D_N PF15705.5 KFQ90893.1 - 8.6e-11 41.8 0.0 1.7e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term WD40 PF00400.32 KFQ90894.1 - 1.6e-34 117.3 11.9 4.1e-08 33.8 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Prp19 PF08606.11 KFQ90894.1 - 3.4e-33 113.4 2.5 3.4e-33 113.4 2.5 1.8 2 0 0 2 2 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 KFQ90894.1 - 1.7e-14 53.8 0.0 0.0029 17.8 0.0 5.1 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain U-box PF04564.15 KFQ90894.1 - 2.3e-06 27.7 0.0 5.1e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 U-box domain Ge1_WD40 PF16529.5 KFQ90894.1 - 8.4e-05 21.7 0.7 1.3 7.9 0.0 3.3 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFQ90894.1 - 0.00033 19.4 0.8 0.028 13.1 0.1 2.3 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KFQ90894.1 - 0.00058 18.5 0.0 0.61 8.6 0.0 2.4 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.11 KFQ90894.1 - 0.00093 19.1 0.0 1.3 8.9 0.0 2.7 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 KFQ90894.1 - 0.034 12.9 0.1 0.88 8.2 0.0 2.2 1 1 0 2 2 2 0 Nup133 N terminal like DUF1830 PF08865.11 KFQ90894.1 - 0.05 13.6 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) zf-Nse PF11789.8 KFQ90894.1 - 0.073 12.9 0.1 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit GP3 PF03076.14 KFQ90894.1 - 0.11 12.6 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Equine arteritis virus GP3 Cep57_MT_bd PF06657.13 KFQ90894.1 - 0.19 12.2 0.5 0.41 11.1 0.1 1.9 2 0 0 2 2 1 0 Centrosome microtubule-binding domain of Cep57 Frtz PF11768.8 KFQ90894.1 - 0.19 10.0 0.0 0.93 7.7 0.0 2.0 1 1 2 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Zona_pellucida PF00100.23 KFQ90895.1 - 1.6e-42 146.1 0.0 2.9e-42 145.3 0.0 1.5 1 0 0 1 1 1 1 Zona pellucida-like domain Trefoil PF00088.18 KFQ90895.1 - 0.00075 19.3 8.7 0.00082 19.2 5.2 2.6 2 0 0 2 2 2 1 Trefoil (P-type) domain Neisseria_TspB PF05616.13 KFQ90895.1 - 0.27 9.7 0.9 0.47 8.9 0.9 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein BAAT_C PF08840.11 KFQ90896.1 - 6.5e-54 183.1 0.0 7.9e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 KFQ90896.1 - 6e-06 26.0 0.0 0.00013 21.6 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 KFQ90896.1 - 0.0013 18.4 0.0 0.0072 16.0 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 KFQ90896.1 - 0.11 11.8 0.0 0.31 10.3 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Cgr1 PF03879.14 KFQ90897.1 - 6.8e-10 39.3 29.1 9.4e-10 38.8 29.1 1.2 1 0 0 1 1 1 1 Cgr1 family RRP36 PF06102.12 KFQ90897.1 - 0.014 15.3 19.9 0.016 15.1 19.9 1.1 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 BLM10_mid PF16507.5 KFQ90897.1 - 0.23 10.0 2.2 0.26 9.9 2.2 1.0 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, mid region HI0933_like PF03486.14 KFQ90897.1 - 4.5 5.8 5.4 5.3 5.6 5.4 1.0 1 0 0 1 1 1 0 HI0933-like protein ESM4 PF15952.5 KFQ90897.1 - 6.4 7.2 9.9 7.4 7.0 9.9 1.1 1 0 0 1 1 1 0 Enhancer of split M4 family CD20 PF04103.15 KFQ90898.1 - 6.2e-11 42.6 3.1 6.6e-11 42.5 3.1 1.0 1 0 0 1 1 1 1 CD20-like family Cobalamin_bind PF01122.19 KFQ90899.1 - 2.3e-18 66.2 0.0 3.2e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic cobalamin-binding protein DUF4430 PF14478.6 KFQ90899.1 - 1.3e-13 51.4 0.0 1.8e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4430) Ribosomal_L16 PF00252.18 KFQ90900.1 - 9.1e-26 90.4 0.0 1.3e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Syntaxin PF00804.25 KFQ90901.1 - 6.8e-59 198.9 15.8 8.8e-59 198.6 15.8 1.1 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KFQ90901.1 - 4.9e-11 42.5 3.2 7.5e-10 38.7 0.8 2.6 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 KFQ90901.1 - 9.6e-10 38.7 6.2 9.6e-10 38.7 6.2 2.2 1 1 1 2 2 2 1 Syntaxin-like protein WXG100 PF06013.12 KFQ90901.1 - 0.032 14.5 4.4 4.4 7.6 0.0 3.4 4 1 0 4 4 4 0 Proteins of 100 residues with WXG GyrB_insert PF18053.1 KFQ90901.1 - 0.035 14.0 0.6 0.035 14.0 0.6 1.9 2 0 0 2 2 2 0 DNA gyrase B subunit insert domain Branch PF02485.21 KFQ90901.1 - 0.039 13.5 0.1 0.056 12.9 0.1 1.3 1 0 0 1 1 1 0 Core-2/I-Branching enzyme DUF3040 PF11239.8 KFQ90901.1 - 0.061 13.6 1.9 0.45 10.8 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) AAA_13 PF13166.6 KFQ90901.1 - 0.071 11.7 13.9 0.091 11.4 13.9 1.1 1 0 0 1 1 1 0 AAA domain Peripla_BP_2 PF01497.18 KFQ90901.1 - 0.074 12.6 1.7 0.11 12.0 0.1 1.9 2 0 0 2 2 2 0 Periplasmic binding protein Syntaxin-6_N PF09177.11 KFQ90901.1 - 0.17 12.4 9.1 0.075 13.6 3.6 2.7 1 1 0 2 2 2 0 Syntaxin 6, N-terminal SapB_1 PF05184.15 KFQ90901.1 - 0.32 11.1 4.8 3.9 7.6 0.2 3.2 2 1 1 3 3 3 0 Saposin-like type B, region 1 RP-C_C PF11800.8 KFQ90901.1 - 0.4 10.7 10.2 1.1 9.3 4.4 2.5 2 1 0 2 2 2 0 Replication protein C C-terminal region DASH_Duo1 PF08651.10 KFQ90901.1 - 1 9.2 5.4 1.8 8.4 0.1 2.9 3 0 0 3 3 3 0 DASH complex subunit Duo1 XhlA PF10779.9 KFQ90901.1 - 1.1 9.5 14.0 11 6.3 3.1 3.7 3 0 0 3 3 3 0 Haemolysin XhlA FlaC_arch PF05377.11 KFQ90901.1 - 2.2 8.8 12.1 1 9.8 0.8 3.9 3 2 0 3 3 3 0 Flagella accessory protein C (FlaC) ALMT PF11744.8 KFQ90901.1 - 2.6 6.8 9.2 2.6 6.8 8.4 1.4 1 1 0 1 1 1 0 Aluminium activated malate transporter DUF2207 PF09972.9 KFQ90901.1 - 3.8 6.2 5.9 0.85 8.3 0.1 2.0 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) ACCA PF03255.14 KFQ90901.1 - 4.4 7.2 8.5 3.7 7.4 2.9 2.5 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit YtxH PF12732.7 KFQ90901.1 - 5.2 7.7 5.7 1.1e+02 3.4 5.7 3.1 1 1 0 1 1 1 0 YtxH-like protein PAT1 PF09770.9 KFQ90902.1 - 7.1e-15 54.4 0.1 7.1e-15 54.4 0.1 3.0 2 2 0 2 2 2 2 Topoisomerase II-associated protein PAT1 Oxysterol_BP PF01237.18 KFQ90903.1 - 1.5e-13 50.4 0.3 1.5e-13 50.4 0.3 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein PH_6 PF15406.6 KFQ90903.1 - 3.5e-05 24.0 0.0 0.00042 20.6 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 KFQ90903.1 - 5.2e-05 23.4 0.2 0.00016 21.9 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KFQ90903.1 - 0.00013 22.4 0.0 0.0004 20.9 0.0 1.8 1 0 0 1 1 1 1 PH domain Syntaxin-6_N PF09177.11 KFQ90903.1 - 0.0032 18.0 5.4 0.043 14.4 2.7 2.7 2 1 1 3 3 3 1 Syntaxin 6, N-terminal betaPIX_CC PF16523.5 KFQ90903.1 - 0.0042 16.9 1.2 0.012 15.4 1.2 1.8 1 0 0 1 1 1 1 betaPIX coiled coil HlyD_D23 PF16576.5 KFQ90903.1 - 0.014 14.6 0.1 0.023 13.9 0.1 1.3 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion MbeD_MobD PF04899.12 KFQ90903.1 - 0.094 12.8 3.5 0.97 9.6 0.7 2.6 2 0 0 2 2 2 0 MbeD/MobD like VGCC_beta4Aa_N PF12052.8 KFQ90903.1 - 0.45 10.7 0.1 0.45 10.7 0.1 2.9 3 0 0 3 3 3 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal DUF3450 PF11932.8 KFQ90903.1 - 5.1 6.3 10.0 3.7 6.8 3.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Oxysterol_BP PF01237.18 KFQ90904.1 - 2e-26 92.8 2.9 2.1e-26 92.7 2.9 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein EF-hand_1 PF00036.32 KFQ90905.1 - 2.7e-25 86.0 9.7 1.2e-08 33.8 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFQ90905.1 - 5.3e-23 81.2 3.8 7.7e-12 45.5 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFQ90905.1 - 1.8e-20 72.5 7.1 9.8e-10 38.1 0.2 3.7 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KFQ90905.1 - 4e-20 70.0 3.7 3.7e-08 32.7 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KFQ90905.1 - 9.5e-17 59.7 13.9 4e-06 26.1 0.1 4.9 4 1 1 5 5 5 3 EF hand Dockerin_1 PF00404.18 KFQ90905.1 - 1.3e-07 31.6 1.4 4.3e-05 23.6 0.7 2.6 2 2 1 3 3 3 2 Dockerin type I domain DIMCO_N PF16844.5 KFQ90905.1 - 0.00022 21.5 0.1 0.00053 20.3 0.1 1.7 1 1 0 1 1 1 1 Dinitrogenase iron-molybdenum cofactor, N-terminal DUF3349 PF11829.8 KFQ90905.1 - 0.00081 20.1 0.0 1.1 10.1 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3349) EF-hand_9 PF14658.6 KFQ90905.1 - 0.0023 18.2 0.6 0.017 15.5 0.1 2.3 2 1 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 KFQ90905.1 - 0.0023 18.2 0.1 0.25 11.7 0.0 2.3 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 KFQ90905.1 - 0.012 15.6 0.7 6.4 6.7 0.1 2.7 2 1 0 2 2 2 0 Tellurite resistance protein TerB EF-hand_4 PF12763.7 KFQ90905.1 - 0.038 13.9 3.1 3.5 7.6 0.1 3.1 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 KFQ90905.1 - 0.087 12.7 0.0 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 Caleosin related protein SpoIIAA-like PF11964.8 KFQ90905.1 - 0.15 13.1 0.3 14 6.8 0.1 2.5 2 1 1 3 3 3 0 SpoIIAA-like POTRA_2 PF08479.11 KFQ90905.1 - 0.16 11.9 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 POTRA domain, ShlB-type WD40 PF00400.32 KFQ90906.1 - 4.5e-08 33.6 1.5 0.0069 17.2 0.1 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ90906.1 - 0.00025 21.3 0.0 0.011 16.0 0.0 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Ig_3 PF13927.6 KFQ90907.1 - 1.4e-08 35.2 0.0 4e-05 24.1 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFQ90907.1 - 1.6e-08 34.7 0.1 6.8e-05 23.0 0.0 3.0 2 1 1 3 3 3 2 Immunoglobulin V-set domain Ig_2 PF13895.6 KFQ90907.1 - 7.3e-08 32.6 0.4 3e-05 24.3 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFQ90907.1 - 9.6e-07 28.9 0.3 0.027 14.6 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFQ90907.1 - 4.7e-06 26.6 0.0 0.00071 19.6 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_6 PF18452.1 KFQ90907.1 - 0.0043 16.6 0.0 3 7.5 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Mlf1IP PF10248.9 KFQ90909.1 - 8.5e-61 204.9 4.3 1e-60 204.6 4.3 1.1 1 0 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein CSN7a_helixI PF18392.1 KFQ90910.1 - 7.8e-21 73.7 3.3 1.4e-20 73.0 3.3 1.4 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain PCI PF01399.27 KFQ90910.1 - 8.6e-08 32.6 0.2 5.5e-07 30.1 0.1 2.1 2 1 0 2 2 2 1 PCI domain DUF4200 PF13863.6 KFQ90910.1 - 0.012 16.0 2.1 0.033 14.6 2.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Ribosomal_S3_C PF00189.20 KFQ90910.1 - 0.013 16.0 0.1 0.024 15.1 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S3, C-terminal domain Band_3_cyto PF07565.13 KFQ90910.1 - 0.32 10.8 3.5 0.44 10.3 3.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain AJAP1_PANP_C PF15298.6 KFQ90911.1 - 1.1e-07 32.2 0.1 9.2e-07 29.3 0.1 2.0 1 1 0 1 1 1 1 AJAP1/PANP C-terminus EphA2_TM PF14575.6 KFQ90911.1 - 0.15 13.0 0.0 0.25 12.3 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain zf-H2C2_2 PF13465.6 KFQ90912.1 - 8e-37 124.1 68.9 1.3e-06 28.6 0.3 9.4 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ90912.1 - 2.4e-33 112.7 79.9 1.8e-05 24.9 3.2 9.4 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ90912.1 - 3.7e-18 64.7 75.1 0.002 18.8 3.0 9.7 9 0 0 9 9 9 7 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFQ90912.1 - 6.4e-05 22.7 6.6 0.0036 17.2 0.5 6.1 7 0 0 7 7 6 2 zinc-finger of a C2HC-type zf-Di19 PF05605.12 KFQ90912.1 - 0.00033 20.9 46.5 0.023 15.0 6.5 5.2 3 1 0 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KFQ90912.1 - 0.00035 20.8 50.8 0.0089 16.3 0.6 8.4 7 1 1 8 8 8 3 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KFQ90912.1 - 0.0059 17.0 40.9 0.35 11.4 3.9 6.0 2 1 3 6 6 5 3 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 KFQ90912.1 - 0.0066 16.2 11.2 0.012 15.4 1.7 9.6 10 1 0 10 10 9 2 C2H2-type zinc-finger domain TerY_C PF15616.6 KFQ90912.1 - 0.23 11.6 17.4 0.61 10.2 0.6 4.0 2 1 2 4 4 4 0 TerY-C metal binding domain zinc_ribbon_9 PF14369.6 KFQ90912.1 - 0.47 10.8 17.2 11 6.4 0.1 6.2 5 1 0 5 5 5 0 zinc-ribbon zf-AN1 PF01428.16 KFQ90912.1 - 0.65 10.2 31.4 13 6.0 0.1 7.5 7 1 0 7 7 7 0 AN1-like Zinc finger Zn-ribbon_8 PF09723.10 KFQ90912.1 - 2.5 8.3 31.0 0.1 12.7 2.4 5.4 3 2 2 5 5 5 0 Zinc ribbon domain zf-met PF12874.7 KFQ90912.1 - 2.6 8.6 61.0 0.27 11.7 2.4 8.8 8 0 0 8 8 8 0 Zinc-finger of C2H2 type zinc-ribbons_6 PF07191.12 KFQ90912.1 - 5.5 7.1 30.1 1.2 9.2 1.1 5.2 2 2 2 4 4 4 0 zinc-ribbons C1_1 PF00130.22 KFQ90912.1 - 5.7 6.9 31.6 1.7 8.6 2.9 6.1 2 2 5 7 7 7 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ING PF12998.7 KFQ90913.1 - 6.2e-27 94.1 2.0 6.2e-27 94.1 2.0 1.9 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KFQ90913.1 - 2.2e-06 27.5 7.6 4.2e-06 26.6 7.6 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KFQ90913.1 - 0.006 16.1 1.1 0.01 15.3 1.1 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KFQ90913.1 - 0.008 16.4 0.5 0.019 15.2 0.5 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain Spc7 PF08317.11 KFQ90913.1 - 0.013 14.4 7.5 0.016 14.1 7.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein AP3D1 PF06375.11 KFQ90913.1 - 0.014 15.6 5.7 0.017 15.3 5.7 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DUF1319 PF07028.11 KFQ90913.1 - 0.13 12.5 1.0 0.62 10.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) SOGA PF11365.8 KFQ90913.1 - 0.19 12.9 11.2 1.5 10.0 5.5 2.9 1 1 1 2 2 2 0 Protein SOGA ABC_tran_CTD PF16326.5 KFQ90913.1 - 0.22 11.8 5.4 0.77 10.0 0.7 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain ORF6C PF10552.9 KFQ90913.1 - 0.32 11.1 7.5 1 9.4 2.2 2.1 2 0 0 2 2 2 0 ORF6C domain DASH_Spc19 PF08287.11 KFQ90913.1 - 7.6 6.4 15.7 1.5 8.7 8.8 2.0 1 1 0 2 2 2 0 Spc19 wnt PF00110.19 KFQ90914.1 - 1.4e-124 415.7 20.3 1.6e-124 415.5 20.3 1.0 1 0 0 1 1 1 1 wnt family 7tm_1 PF00001.21 KFQ90915.1 - 1.8e-48 165.2 21.2 2.2e-48 164.9 21.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Methyltr_RsmB-F PF01189.17 KFQ90916.1 - 2.7e-80 268.7 0.0 4.1e-80 268.2 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KFQ90916.1 - 1.7e-08 34.8 0.0 3.7e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 KFQ90916.1 - 0.0012 19.0 0.0 0.0023 18.1 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 KFQ90916.1 - 0.0015 19.2 0.0 0.0032 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFQ90916.1 - 0.0018 18.1 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFQ90916.1 - 0.0079 16.0 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 KFQ90916.1 - 0.022 14.5 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein DUF2431 PF10354.9 KFQ90916.1 - 0.067 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Methyltransf_15 PF09445.10 KFQ90916.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Filament PF00038.21 KFQ90917.1 - 2.6e-15 56.8 28.3 3.8e-10 39.8 3.6 2.8 3 0 0 3 3 3 2 Intermediate filament protein HlyE PF06109.13 KFQ90917.1 - 0.13 11.5 0.0 0.13 11.5 0.0 1.9 3 0 0 3 3 3 0 Haemolysin E (HlyE) T2SSF PF00482.23 KFQ90917.1 - 0.17 11.8 0.3 0.4 10.6 0.3 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F PAPA-1 PF04795.12 KFQ90917.1 - 0.42 11.4 0.1 0.42 11.4 0.1 3.2 3 1 1 4 4 4 0 PAPA-1-like conserved region Snapin_Pallidin PF14712.6 KFQ90917.1 - 2.6 8.5 14.3 0.55 10.7 4.4 3.1 3 1 0 3 3 3 0 Snapin/Pallidin DUF883 PF05957.13 KFQ90917.1 - 4.1 8.1 10.1 0.43 11.2 0.5 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Gp_dh_C PF02800.20 KFQ90918.1 - 4e-70 234.5 0.0 6.5e-70 233.8 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KFQ90918.1 - 1.5e-34 118.3 0.1 4.2e-34 116.9 0.1 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain OstA PF03968.14 KFQ90918.1 - 0.017 15.3 0.0 0.044 14.0 0.0 1.7 1 0 0 1 1 1 0 OstA-like protein MRP-L51 PF10244.9 KFQ90919.1 - 7.1e-37 125.5 0.6 8.3e-37 125.3 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit DUF4817 PF16087.5 KFQ90919.1 - 0.11 12.3 0.7 14 5.6 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) Synaptobrevin PF00957.21 KFQ90920.1 - 2.6e-33 113.7 2.1 2.8e-33 113.5 2.1 1.0 1 0 0 1 1 1 1 Synaptobrevin MCU PF04678.13 KFQ90920.1 - 0.0041 17.2 0.4 0.0048 17.0 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Duffy_binding PF05424.11 KFQ90920.1 - 0.034 14.2 0.1 0.039 14.0 0.1 1.1 1 0 0 1 1 1 0 Duffy binding domain PRIMA1 PF16101.5 KFQ90920.1 - 0.048 13.7 0.4 0.085 12.9 0.4 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SNARE PF05739.19 KFQ90920.1 - 4.4 7.4 9.8 0.85 9.7 5.7 1.9 2 0 0 2 2 2 0 SNARE domain ASC PF00858.24 KFQ90921.1 - 4.6e-108 362.0 13.2 5.7e-108 361.7 13.2 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel V-set PF07686.17 KFQ90922.1 - 1.1e-21 77.0 0.2 3.3e-16 59.4 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.6 KFQ90922.1 - 6.5e-16 58.7 3.1 1.2e-06 29.1 0.7 3.0 3 0 0 3 3 3 2 Immunoglobulin domain C1-set PF07654.15 KFQ90922.1 - 7.8e-14 51.8 0.1 2.2e-13 50.4 0.1 1.9 1 0 0 1 1 1 1 Immunoglobulin C1-set domain ig PF00047.25 KFQ90922.1 - 1.1e-12 47.9 0.5 2.9e-07 30.6 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFQ90922.1 - 4.5e-11 42.7 0.0 5.8e-05 23.1 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFQ90922.1 - 7.7e-07 29.4 0.2 0.036 14.4 0.1 3.1 2 1 0 2 2 2 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFQ90922.1 - 0.013 15.5 0.0 0.05 13.7 0.0 2.1 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 KFQ90922.1 - 0.067 13.3 3.0 0.07 13.2 0.1 2.5 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain VanW PF04294.13 KFQ90922.1 - 0.085 12.5 0.1 15 5.2 0.0 2.3 2 0 0 2 2 2 0 VanW like protein DUF4083 PF13314.6 KFQ90922.1 - 0.11 12.4 0.1 3.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Cytomega_TRL10 PF06084.11 KFQ90922.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein LRR_4 PF12799.7 KFQ90923.1 - 5.2e-24 83.9 21.6 1.7e-08 34.6 0.6 5.7 5 1 0 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFQ90923.1 - 5e-17 61.4 28.3 5.9e-08 32.4 3.7 5.5 2 1 5 7 7 7 6 Leucine rich repeat LRR_9 PF14580.6 KFQ90923.1 - 1.8e-16 60.1 3.9 4.1e-13 49.2 0.4 3.0 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 KFQ90923.1 - 1.5e-08 34.0 17.9 1.1 9.5 0.1 8.8 9 1 1 10 10 10 4 Leucine Rich repeat LRR_1 PF00560.33 KFQ90923.1 - 0.014 15.8 19.1 5.2 8.0 0.1 6.9 6 3 0 6 6 6 0 Leucine Rich Repeat Enolase_C PF00113.22 KFQ90924.1 - 4e-158 525.3 0.0 5e-158 525.0 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KFQ90924.1 - 1.8e-59 199.6 0.0 3.2e-59 198.8 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KFQ90924.1 - 2.8e-09 36.9 0.0 4.1e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KFQ90924.1 - 3.5e-05 23.1 0.3 7.7e-05 22.0 0.3 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus P_C10 PF14974.6 KFQ90925.1 - 5.7e-41 138.8 0.1 6.5e-41 138.6 0.1 1.0 1 0 0 1 1 1 1 Protein C10 FAST_2 PF08368.12 KFQ90925.1 - 0.011 16.5 0.0 0.028 15.2 0.0 1.6 1 1 1 2 2 2 0 FAST kinase-like protein, subdomain 2 DUF4309 PF14172.6 KFQ90925.1 - 0.056 13.5 0.0 4.1 7.4 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4309) Y_phosphatase PF00102.27 KFQ90926.1 - 8.6e-79 264.4 0.2 1.3e-78 263.8 0.2 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase SH2 PF00017.24 KFQ90926.1 - 3.8e-46 155.1 0.1 1.7e-21 76.1 0.0 3.0 3 0 0 3 3 3 2 SH2 domain DSPc PF00782.20 KFQ90926.1 - 1.6e-05 24.7 0.1 7e-05 22.6 0.1 2.0 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFQ90926.1 - 0.00061 19.8 0.0 0.002 18.2 0.0 1.9 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFQ90926.1 - 0.0096 16.1 0.1 0.057 13.5 0.0 2.5 2 1 0 2 2 2 1 Inositol hexakisphosphate MRNIP PF15749.5 KFQ90926.1 - 0.094 13.4 0.1 0.094 13.4 0.1 2.4 2 0 0 2 2 2 0 MRN-interacting protein Band_7 PF01145.25 KFQ90927.1 - 3.3e-17 63.1 5.0 4.7e-17 62.6 5.0 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.8 KFQ90927.1 - 0.00029 21.0 1.9 0.00056 20.0 1.9 1.5 1 0 0 1 1 1 1 Mediator complex subunit 2 EMG1 PF03587.14 KFQ90928.1 - 1.5e-79 266.2 0.0 1.6e-79 266.1 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase MBOAT PF03062.19 KFQ90929.1 - 2.4e-65 221.2 13.6 2.4e-65 221.2 13.6 2.2 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family CUB PF00431.20 KFQ90930.1 - 3.3e-18 66.0 0.1 7.8e-18 64.8 0.1 1.6 1 1 0 1 1 1 1 CUB domain FXa_inhibition PF14670.6 KFQ90930.1 - 2.5e-09 37.2 6.6 4.8e-09 36.4 6.6 1.5 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 KFQ90930.1 - 1.1e-05 25.6 8.1 1.9e-05 24.8 8.1 1.4 1 0 0 1 1 1 1 Calcium-binding EGF domain EGF PF00008.27 KFQ90930.1 - 0.0047 17.2 7.0 0.011 16.1 7.0 1.6 1 0 0 1 1 1 1 EGF-like domain CUB_2 PF02408.20 KFQ90930.1 - 0.042 13.6 0.9 0.11 12.2 0.2 2.0 2 1 0 2 2 2 0 CUB-like domain hEGF PF12661.7 KFQ90930.1 - 0.053 14.2 5.1 0.13 13.0 5.1 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF CUB PF00431.20 KFQ90931.1 - 8.3e-52 174.2 0.1 5.6e-28 97.5 0.1 2.4 2 0 0 2 2 2 2 CUB domain Trypsin PF00089.26 KFQ90931.1 - 6.8e-50 169.9 0.0 1e-49 169.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin Sushi PF00084.20 KFQ90931.1 - 3.7e-17 62.7 18.2 3.9e-11 43.4 0.9 3.8 3 0 0 3 3 3 2 Sushi repeat (SCR repeat) FXa_inhibition PF14670.6 KFQ90931.1 - 3.4e-10 40.0 12.0 2.2e-09 37.4 9.2 3.0 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFQ90931.1 - 4.9e-05 23.2 7.8 0.00087 19.2 5.2 3.1 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF_CA PF07645.15 KFQ90931.1 - 0.00039 20.6 10.4 0.00053 20.1 8.3 2.5 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF PF00008.27 KFQ90931.1 - 0.0017 18.6 6.0 0.011 16.0 6.0 2.4 1 0 0 1 1 1 1 EGF-like domain CUB_2 PF02408.20 KFQ90931.1 - 0.003 17.3 0.4 0.81 9.5 0.0 3.0 3 0 0 3 3 3 1 CUB-like domain Plasmod_Pvs28 PF06247.11 KFQ90931.1 - 0.24 11.8 2.7 8.3 6.8 0.0 2.9 2 0 0 2 2 2 0 Pvs28 EGF domain hEGF PF12661.7 KFQ90931.1 - 0.29 11.8 7.8 2.3 9.0 7.8 2.8 1 0 0 1 1 1 0 Human growth factor-like EGF Lipocalin_7 PF14651.6 KFQ90932.1 - 0.047 13.6 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Cadherin PF00028.17 KFQ90933.1 - 1.1e-12 48.1 0.0 1.9e-06 28.2 0.0 2.6 2 0 0 2 2 2 2 Cadherin domain Laminin_G_3 PF13385.6 KFQ90933.1 - 2.4e-06 27.8 0.0 7.9e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 KFQ90933.1 - 0.014 16.0 0.0 0.037 14.6 0.0 1.7 1 0 0 1 1 1 0 Laminin G domain Mito_carr PF00153.27 KFQ90934.1 - 4.1e-63 209.3 0.2 1.9e-21 75.8 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TPR_1 PF00515.28 KFQ90935.1 - 3.4e-24 83.6 1.6 3.3e-06 26.7 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ90935.1 - 1e-19 69.0 5.8 0.00016 21.5 0.4 6.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ90935.1 - 3.1e-18 65.2 0.4 3.3e-05 23.5 0.1 5.3 3 1 3 6 6 6 3 TPR repeat TPR_16 PF13432.6 KFQ90935.1 - 1.7e-17 63.8 1.1 3.7e-06 27.5 0.4 4.7 2 2 1 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ90935.1 - 6e-17 60.4 0.1 0.00082 19.4 0.0 5.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ90935.1 - 2.1e-14 52.8 0.7 0.046 14.1 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ90935.1 - 1.5e-13 50.3 13.5 0.01 16.6 0.2 7.3 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ90935.1 - 6.6e-13 49.0 2.4 0.0026 18.2 0.0 4.7 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ90935.1 - 2.2e-10 40.7 5.6 9.2e-05 22.7 0.1 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ90935.1 - 1.6e-09 37.1 2.2 0.25 11.4 0.0 6.1 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_20 PF14561.6 KFQ90935.1 - 4e-07 30.3 1.7 0.37 11.2 0.1 4.8 3 2 3 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFQ90935.1 - 7.8e-07 29.2 5.9 0.058 13.5 0.2 3.5 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ90935.1 - 4.4e-06 26.4 3.1 0.05 13.5 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ90935.1 - 2.1e-05 24.7 2.4 0.067 13.4 0.1 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KFQ90935.1 - 6.7e-05 23.3 5.5 4.1 8.2 0.1 6.3 7 0 0 7 7 6 1 Tetratricopeptide repeat DUF1641 PF07849.11 KFQ90935.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) Secretin_N_2 PF07655.13 KFQ90935.1 - 0.058 13.9 0.1 0.15 12.6 0.1 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain MAS20 PF02064.15 KFQ90935.1 - 0.067 13.3 0.9 9.7 6.3 0.0 3.0 2 2 1 3 3 3 0 MAS20 protein import receptor BTAD PF03704.17 KFQ90935.1 - 0.28 11.6 5.1 3.2 8.2 0.0 3.9 4 1 0 4 4 4 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 KFQ90935.1 - 0.5 10.5 1.9 41 4.3 0.0 3.8 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.9 KFQ90935.1 - 0.56 9.7 4.2 31 4.1 0.0 3.9 4 0 0 4 4 4 0 SHNi-TPR 7tm_4 PF13853.6 KFQ90936.1 - 1.2e-41 143.3 21.7 1.5e-41 143.0 21.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ90936.1 - 1.2e-20 74.0 19.3 1.9e-20 73.3 19.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Gaa1 PF04114.14 KFQ90936.1 - 0.0026 16.8 12.9 0.0046 16.0 12.9 1.4 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component Pkinase_Tyr PF07714.17 KFQ90937.1 - 2.5e-97 325.2 0.0 3.7e-97 324.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.19 KFQ90937.1 - 7.7e-51 172.7 0.9 1.2e-50 172.1 0.9 1.3 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.25 KFQ90937.1 - 7.5e-48 163.2 0.0 1.1e-47 162.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 KFQ90937.1 - 1.1e-24 86.5 0.1 4.8e-12 46.0 0.0 2.7 3 0 0 3 3 2 2 Fibronectin type III domain SAM_1 PF00536.30 KFQ90937.1 - 4.7e-21 75.0 0.0 1.1e-20 73.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFQ90937.1 - 1.1e-17 63.9 0.0 2.2e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EphA2_TM PF14575.6 KFQ90937.1 - 8.9e-15 55.3 0.0 1.7e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Pur_ac_phosph_N PF16656.5 KFQ90937.1 - 9.5e-08 32.5 0.0 6.5e-05 23.4 0.0 2.7 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Ephrin_rec_like PF07699.13 KFQ90937.1 - 1.3e-06 28.1 3.4 1.3e-06 28.1 3.4 3.4 2 1 1 3 3 3 1 Putative ephrin-receptor like Tissue_fac PF01108.17 KFQ90937.1 - 0.012 15.5 0.0 0.39 10.6 0.0 2.4 2 0 0 2 2 2 0 Tissue factor Kdo PF06293.14 KFQ90937.1 - 0.031 13.7 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFQ90937.1 - 0.032 13.2 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Tudor_4 PF18358.1 KFQ90937.1 - 0.15 11.7 0.1 19 4.9 0.0 2.6 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain Pkinase_fungal PF17667.1 KFQ90937.1 - 0.18 10.5 0.0 0.27 9.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase PMP1_2 PF08114.11 KFQ90937.1 - 0.58 9.9 3.8 2.5 7.9 0.0 2.5 2 0 0 2 2 2 0 ATPase proteolipid family LIM PF00412.22 KFQ90938.1 - 8e-34 115.7 34.0 6.1e-13 48.8 8.6 3.2 3 0 0 3 3 3 3 LIM domain zf_C2H2_13 PF18508.1 KFQ90938.1 - 0.02 14.5 1.2 0.072 12.7 0.2 2.4 2 0 0 2 2 2 0 Zinc finger domain DUF2321 PF10083.9 KFQ90938.1 - 2.5 7.7 14.2 5.1 6.7 5.7 2.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) FAM131 PF15010.6 KFQ90939.1 - 3e-100 336.0 5.6 5.9e-100 335.0 5.6 1.4 1 1 0 1 1 1 1 Putative cell signalling Peptidase_C14 PF00656.22 KFQ90940.1 - 9.4e-44 150.2 0.3 4.5e-43 148.0 0.2 1.9 2 0 0 2 2 2 1 Caspase domain CARD PF00619.21 KFQ90940.1 - 5e-20 71.3 0.7 1.1e-19 70.2 0.7 1.6 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 KFQ90940.1 - 1.2e-06 28.5 0.8 2.2e-06 27.6 0.8 1.5 1 0 0 1 1 1 1 Caspase recruitment domain TMEM51 PF15345.6 KFQ90941.1 - 0.039 13.8 0.5 0.046 13.6 0.5 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Rap_GAP PF02145.15 KFQ90942.1 - 9e-65 217.7 0.0 1.4e-64 217.1 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP GoLoco PF02188.17 KFQ90942.1 - 0.00016 21.1 1.6 0.00034 20.0 1.6 1.6 1 0 0 1 1 1 1 GoLoco motif DUF4667 PF15700.5 KFQ90942.1 - 0.017 15.3 3.1 0.025 14.7 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) DSBA PF01323.20 KFQ90943.1 - 4e-37 127.9 0.0 4.9e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain EAL PF00563.20 KFQ90943.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 EAL domain TAF PF02969.17 KFQ90943.1 - 0.17 12.1 0.1 0.48 10.6 0.1 1.7 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) Tubulin-binding PF00418.19 KFQ90944.1 - 6.7e-63 208.3 21.1 9.9e-16 57.5 2.6 5.5 5 0 0 5 5 5 5 Tau and MAP protein, tubulin-binding repeat RII_binding_1 PF10522.9 KFQ90944.1 - 0.00043 20.2 2.9 0.0011 18.9 2.9 1.7 1 0 0 1 1 1 1 RII binding domain UNC80 PF15778.5 KFQ90945.1 - 9.1e-80 266.7 0.0 1.2e-79 266.3 0.0 1.1 1 0 0 1 1 1 1 Cation channel complex component UNC80 Ribul_P_3_epim PF00834.19 KFQ90947.1 - 9.4e-45 152.4 0.1 1.2e-44 152.1 0.1 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 KFQ90947.1 - 0.0036 17.1 0.0 0.0051 16.6 0.0 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.24 KFQ90947.1 - 0.0057 16.3 0.0 0.008 15.8 0.0 1.3 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family TMP-TENI PF02581.17 KFQ90947.1 - 0.0065 15.8 0.0 0.011 15.0 0.0 1.4 1 1 0 1 1 1 1 Thiamine monophosphate synthase His_biosynth PF00977.21 KFQ90947.1 - 0.075 12.5 0.0 0.28 10.6 0.0 1.8 1 1 1 2 2 2 0 Histidine biosynthesis protein PEHE PF15275.6 KFQ90948.1 - 5.2e-21 75.6 8.2 5.2e-21 75.6 8.2 4.6 5 0 0 5 5 5 2 PEHE domain Acyl-CoA_dh_1 PF00441.24 KFQ90949.1 - 4.6e-42 143.7 0.2 6.4e-42 143.3 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFQ90949.1 - 3.3e-30 105.0 0.0 7.1e-30 104.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFQ90949.1 - 1.9e-25 88.9 0.0 4.5e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFQ90949.1 - 2.3e-08 34.4 0.0 3.2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 KFQ90949.1 - 0.032 14.8 0.0 0.078 13.5 0.0 1.7 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal DUF5339 PF17274.2 KFQ90949.1 - 0.2 12.5 0.7 0.4 11.6 0.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5339) EF-hand_1 PF00036.32 KFQ90950.1 - 1.1e-11 43.4 3.5 0.011 15.2 0.1 5.0 4 2 1 5 5 5 4 EF hand EF-hand_6 PF13405.6 KFQ90950.1 - 1.5e-11 43.3 0.7 0.00023 20.8 0.2 4.4 4 1 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 KFQ90950.1 - 3.3e-11 43.5 0.2 6.9e-05 23.2 0.1 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFQ90950.1 - 1.2e-06 28.3 2.0 0.044 13.6 0.1 3.4 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.6 KFQ90950.1 - 0.00037 20.8 0.0 0.53 10.7 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain Cas9_REC PF16592.5 KFQ90950.1 - 0.018 13.8 0.1 0.02 13.7 0.1 1.1 1 0 0 1 1 1 0 REC lobe of CRISPR-associated endonuclease Cas9 DUF2267 PF10025.9 KFQ90950.1 - 0.1 12.9 0.2 0.61 10.4 0.2 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) LANC_like PF05147.13 KFQ90951.1 - 5.7e-107 357.3 0.2 7.4e-107 357.0 0.2 1.1 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Glyco_hydro_127 PF07944.12 KFQ90951.1 - 0.00061 18.4 0.3 0.37 9.2 0.1 2.3 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_88 PF07470.13 KFQ90951.1 - 0.0045 16.1 0.9 2.1 7.3 0.4 2.5 2 1 0 2 2 2 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 KFQ90951.1 - 0.026 14.0 4.8 1 8.8 0.0 3.6 3 1 0 4 4 4 0 D-glucuronyl C5-epimerase C-terminus GlcNAc_2-epim PF07221.11 KFQ90951.1 - 0.17 11.1 0.2 5.5 6.1 0.0 2.4 2 1 1 3 3 3 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) CPSase_L_D2 PF02786.17 KFQ90952.1 - 1.8e-113 377.3 0.5 1.3e-81 273.1 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 KFQ90952.1 - 2.1e-44 150.4 0.0 5.3e-44 149.1 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.19 KFQ90952.1 - 8.2e-38 129.5 0.2 1.7e-37 128.4 0.2 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain GATase PF00117.28 KFQ90952.1 - 8.3e-36 123.5 0.0 1.5e-35 122.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I ATP-grasp PF02222.22 KFQ90952.1 - 9.8e-18 64.3 0.5 3.8e-09 36.3 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.22 KFQ90952.1 - 1.2e-16 60.6 0.0 1e-15 57.7 0.0 2.5 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 KFQ90952.1 - 4e-14 52.6 0.9 1.2e-06 28.2 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KFQ90952.1 - 5.4e-12 45.6 0.0 1.9e-05 24.4 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 KFQ90952.1 - 0.00013 22.0 0.1 0.17 12.0 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain CPSase_C PF18302.1 KFQ90952.1 - 0.0038 17.3 1.0 0.011 15.9 1.0 1.8 1 0 0 1 1 1 1 Carbamoyl phosphate synthetase C-terminal domain AP_endonuc_2 PF01261.24 KFQ90952.1 - 0.016 14.7 0.0 1.5 8.2 0.0 3.8 5 0 0 5 5 5 0 Xylose isomerase-like TIM barrel ATP-grasp_5 PF13549.6 KFQ90952.1 - 0.11 11.9 0.1 15 4.9 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain Pkinase_Tyr PF07714.17 KFQ90954.1 - 5.8e-92 307.6 0.0 1.1e-91 306.7 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase GF_recep_IV PF14843.6 KFQ90954.1 - 9.3e-52 174.3 70.3 2.6e-47 159.9 27.4 4.5 2 1 1 3 3 3 3 Growth factor receptor domain IV Pkinase PF00069.25 KFQ90954.1 - 6.7e-40 137.1 0.0 1.1e-39 136.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.20 KFQ90954.1 - 1.3e-32 112.7 76.9 3.8e-25 88.5 33.4 4.2 2 1 2 4 4 4 3 Furin-like cysteine rich region Recep_L_domain PF01030.24 KFQ90954.1 - 1.8e-27 95.7 0.5 3.4e-27 94.8 0.5 1.5 1 0 0 1 1 1 1 Receptor L domain Haspin_kinase PF12330.8 KFQ90954.1 - 0.0017 17.4 0.0 0.0028 16.7 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFQ90954.1 - 0.0082 16.1 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFQ90954.1 - 0.013 14.9 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF3951 PF13131.6 KFQ90954.1 - 0.049 13.8 1.6 0.11 12.7 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) Adeno_E3_CR2 PF02439.15 KFQ90954.1 - 0.15 11.9 2.1 0.42 10.4 2.1 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 zf-C2H2 PF00096.26 KFQ90955.1 - 1.1e-15 57.1 43.1 8e-05 22.9 1.3 7.0 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ90955.1 - 7.9e-15 54.5 37.8 9.1e-08 32.2 2.7 7.4 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ90955.1 - 1.5e-10 41.0 44.6 0.00089 19.9 1.1 7.3 7 0 0 7 7 7 4 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFQ90955.1 - 5.2e-06 26.1 5.4 6.4e-05 22.6 0.8 5.2 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-MYND PF01753.18 KFQ90955.1 - 0.021 14.9 8.6 0.23 11.6 0.0 3.6 3 1 0 3 3 3 0 MYND finger zf-C2H2_jaz PF12171.8 KFQ90955.1 - 0.1 12.9 22.5 0.9 9.9 0.0 5.5 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFQ90955.1 - 0.15 11.9 0.0 0.15 11.9 0.0 3.3 3 1 1 4 4 4 0 GAGA factor zf-C2HE PF16278.5 KFQ90955.1 - 0.21 12.1 28.0 0.82 10.2 1.0 5.8 5 1 1 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 KFQ90955.1 - 0.29 11.6 0.2 0.29 11.6 0.2 6.3 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFQ90955.1 - 0.92 9.8 15.9 0.36 11.2 3.7 3.7 3 1 0 3 3 3 0 C2H2-type zinc ribbon DUF3268 PF11672.8 KFQ90955.1 - 1.5 9.1 8.3 2 8.8 0.3 3.1 3 0 0 3 3 3 0 zinc-finger-containing domain zf-TRAF PF02176.18 KFQ90955.1 - 3 8.6 15.2 0.72 10.6 4.2 3.5 3 0 0 3 3 3 0 TRAF-type zinc finger zf-C2H2_11 PF16622.5 KFQ90955.1 - 6.3 6.7 18.7 0.12 12.2 0.3 4.3 4 0 0 4 4 4 0 zinc-finger C2H2-type DUF4893 PF16233.5 KFQ90956.1 - 0.04 13.5 0.1 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4893) DUF745 PF05335.13 KFQ90956.1 - 0.52 10.0 7.1 0.33 10.7 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF745) Cep57_CLD_2 PF14197.6 KFQ90956.1 - 1.1 9.4 13.4 2.8 8.1 0.3 3.8 3 3 2 5 5 5 0 Centrosome localisation domain of PPC89 YabA PF06156.13 KFQ90956.1 - 1.2 9.9 9.3 0.58 10.8 2.2 2.9 2 1 1 3 3 3 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 KFQ90956.1 - 1.2 9.4 9.9 0.53 10.5 4.4 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding NYD-SP28_assoc PF14775.6 KFQ90956.1 - 2.7 8.2 8.5 15 5.8 0.3 3.5 2 1 1 3 3 3 0 Sperm tail C-terminal domain VWC PF00093.18 KFQ90957.1 - 5e-07 29.9 52.1 7.6e-06 26.2 17.1 3.2 3 0 0 3 3 3 3 von Willebrand factor type C domain Pacifastin_I PF05375.13 KFQ90957.1 - 0.12 12.1 28.5 0.038 13.7 7.3 3.9 3 0 0 3 3 3 0 Pacifastin inhibitor (LCMII) zf-CCCH_2 PF14608.6 KFQ90957.1 - 0.65 10.6 0.1 0.65 10.6 0.1 5.0 5 0 0 5 5 5 0 RNA-binding, Nab2-type zinc finger ABC_tran PF00005.27 KFQ90958.1 - 1.2e-53 181.3 0.0 8.5e-29 100.8 0.0 3.1 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KFQ90958.1 - 1.5e-49 169.0 44.7 7.9e-29 100.8 14.5 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KFQ90958.1 - 2.2e-26 93.4 0.0 7.1e-09 35.9 0.0 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 KFQ90958.1 - 0.005 17.5 0.0 0.022 15.5 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) IstB_IS21 PF01695.17 KFQ90958.1 - 0.0073 16.1 1.1 0.7 9.6 0.0 3.2 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_23 PF13476.6 KFQ90958.1 - 0.02 15.4 0.4 0.02 15.4 0.4 4.2 4 1 0 4 4 3 0 AAA domain AAA_16 PF13191.6 KFQ90958.1 - 0.05 14.0 0.0 8.6 6.7 0.0 2.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 KFQ90958.1 - 0.056 13.2 3.4 0.99 9.2 0.4 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFQ90958.1 - 0.063 13.2 1.0 5.5 6.9 0.1 2.6 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 KFQ90958.1 - 0.1 12.3 0.0 4.3 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain CathepsinC_exc PF08773.11 KFQ90958.1 - 0.13 12.6 0.2 0.28 11.5 0.2 1.6 1 0 0 1 1 1 0 Cathepsin C exclusion domain MMR_HSR1 PF01926.23 KFQ90958.1 - 0.13 12.4 0.0 4.2 7.5 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRP54 PF00448.22 KFQ90958.1 - 1.7 8.2 6.7 1.8 8.1 0.2 2.6 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_15 PF13175.6 KFQ90958.1 - 5.6 6.6 18.5 0.53 9.9 0.0 4.2 5 0 0 5 5 4 0 AAA ATPase domain AICARFT_IMPCHas PF01808.18 KFQ90959.1 - 6.5e-87 291.7 0.0 1.1e-86 291.0 0.0 1.4 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KFQ90959.1 - 1.6e-24 85.9 0.0 3.1e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain PucR PF07905.11 KFQ90959.1 - 0.052 13.8 0.0 3 8.1 0.0 2.6 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family fn3 PF00041.21 KFQ90960.1 - 1.3e-263 852.3 77.9 2.4e-20 72.7 0.6 17.3 17 0 0 17 17 17 17 Fibronectin type III domain fn1 PF00039.18 KFQ90960.1 - 3.6e-149 484.7 168.5 5e-15 55.4 4.5 12.8 12 0 0 12 12 12 12 Fibronectin type I domain Pur_ac_phosph_N PF16656.5 KFQ90960.1 - 3.1e-32 111.0 55.5 0.00077 20.0 0.0 19.7 16 6 0 16 16 16 10 Purple acid Phosphatase, N-terminal domain fn2 PF00040.19 KFQ90960.1 - 5.3e-31 106.6 29.5 1.4e-16 60.4 7.2 3.9 3 0 0 3 3 2 2 Fibronectin type II domain DUF2369 PF10179.9 KFQ90960.1 - 1.2e-26 92.9 14.0 0.19 12.1 0.0 13.8 13 1 1 14 14 14 7 Uncharacterised conserved protein (DUF2369) Interfer-bind PF09294.10 KFQ90960.1 - 1e-18 67.5 0.0 0.41 11.0 0.0 12.4 14 0 0 14 14 13 2 Interferon-alpha/beta receptor, fibronectin type III DUF4959 PF16323.5 KFQ90960.1 - 1.4e-11 44.6 5.2 0.75 10.1 0.0 8.5 9 0 0 9 9 9 2 Domain of unknown function (DUF4959) DUF4912 PF16258.5 KFQ90960.1 - 9.3e-07 29.1 0.0 5.7 7.2 0.0 7.3 8 0 0 8 8 8 1 Domain of unknown function (DUF4912) TILa PF12714.7 KFQ90960.1 - 0.0011 18.9 1.5 0.0011 18.9 1.5 11.4 5 3 7 12 12 12 1 TILa domain fn3_2 PF16893.5 KFQ90960.1 - 0.0042 17.2 9.9 0.58 10.3 0.0 7.4 8 1 0 8 8 7 1 Fibronectin type III domain MG4 PF17789.1 KFQ90960.1 - 0.011 15.8 0.2 0.095 12.9 0.2 2.7 1 0 0 1 1 1 0 Macroglobulin domain MG4 DUF1410 PF07198.11 KFQ90960.1 - 0.012 16.1 6.6 38 4.9 0.0 7.2 8 0 0 8 8 8 0 Protein of unknown function (DUF1410) Glyco_hydro_66 PF13199.6 KFQ90960.1 - 0.019 13.6 7.3 19 3.7 0.0 6.1 5 2 2 8 8 8 0 Glycosyl hydrolase family 66 Big_10 PF17964.1 KFQ90960.1 - 2.4 8.1 7.3 5.8 6.9 0.1 4.5 4 0 0 4 4 4 0 Bacterial Ig domain Arylsulfotran_N PF17425.2 KFQ90960.1 - 8.4 6.5 26.5 0.8 9.8 0.4 7.7 9 0 0 9 9 9 0 Arylsulfotransferase Ig-like domain MREG PF15812.5 KFQ90961.1 - 2e-70 235.9 4.0 2.3e-70 235.7 4.0 1.0 1 0 0 1 1 1 1 Melanoregulin AIP3 PF03915.13 KFQ90961.1 - 0.011 14.9 0.2 0.013 14.6 0.2 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 COG5 PF10392.9 KFQ90961.1 - 0.038 14.2 0.3 0.053 13.7 0.3 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Lipoprotein_6 PF01441.19 KFQ90961.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 1 0 1 1 1 0 Lipoprotein Methyltransf_11 PF08241.12 KFQ90962.1 - 1.2e-24 86.8 0.0 5.5e-24 84.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFQ90962.1 - 4e-22 78.7 0.0 1.3e-21 77.1 0.0 1.8 2 1 1 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFQ90962.1 - 1.1e-14 54.5 0.0 1.7e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFQ90962.1 - 1.2e-12 47.6 0.0 2.1e-12 46.9 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KFQ90962.1 - 1.3e-11 44.6 0.0 1.8e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFQ90962.1 - 1.8e-11 44.6 0.0 3e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KFQ90962.1 - 8.8e-08 32.3 0.0 2.5e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase TPMT PF05724.11 KFQ90962.1 - 0.00032 20.4 0.0 0.0005 19.8 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.20 KFQ90962.1 - 0.00062 19.1 0.0 0.0015 17.9 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 KFQ90962.1 - 0.0023 16.5 0.0 0.0031 16.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 KFQ90962.1 - 0.0029 17.2 0.0 0.0082 15.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KFQ90962.1 - 0.0041 17.1 0.0 0.0079 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFQ90962.1 - 0.0042 16.5 0.0 0.0064 15.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.12 KFQ90962.1 - 0.0098 15.7 0.0 0.019 14.7 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF938) tRNA_U5-meth_tr PF05958.11 KFQ90962.1 - 0.024 13.6 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DREV PF05219.12 KFQ90962.1 - 0.027 13.6 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_33 PF10017.9 KFQ90962.1 - 0.034 13.3 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent N6_N4_Mtase PF01555.18 KFQ90962.1 - 0.049 13.3 0.0 4.4 6.9 0.0 2.5 2 1 0 2 2 2 0 DNA methylase Methyltransf_15 PF09445.10 KFQ90962.1 - 0.12 11.9 0.0 0.32 10.6 0.0 1.7 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase FtsJ PF01728.19 KFQ90962.1 - 0.16 12.1 0.0 0.55 10.3 0.0 1.7 1 1 1 2 2 2 0 FtsJ-like methyltransferase UQ_con PF00179.26 KFQ90963.1 - 3.4e-29 101.3 0.0 4e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme LRRFIP PF09738.9 KFQ90965.1 - 5.9e-75 252.5 91.1 4.9e-44 151.0 24.8 6.0 2 1 3 5 5 5 3 LRRFIP family BRE1 PF08647.11 KFQ90965.1 - 0.0018 18.3 10.2 0.0018 18.3 10.2 5.9 4 2 1 5 5 5 1 BRE1 E3 ubiquitin ligase TPR_MLP1_2 PF07926.12 KFQ90965.1 - 0.015 15.3 11.9 0.015 15.3 11.9 5.6 3 2 1 4 4 4 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 KFQ90965.1 - 0.016 15.7 11.4 0.016 15.7 11.4 5.1 2 1 3 5 5 5 0 Apg6 coiled-coil region HALZ PF02183.18 KFQ90965.1 - 0.072 13.3 24.3 1.3 9.3 0.5 5.8 5 1 0 5 5 5 0 Homeobox associated leucine zipper Tweety PF04906.13 KFQ90965.1 - 4.5 5.8 18.9 0.4 9.3 3.5 3.9 2 2 3 5 5 5 0 Tweety DUF4462 PF14692.6 KFQ90966.1 - 0.12 11.9 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Ras PF00071.22 KFQ90967.1 - 1.1e-54 184.5 0.1 1.3e-54 184.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ90967.1 - 2.3e-30 105.3 0.0 3.8e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ90967.1 - 1.2e-15 57.4 0.0 1.5e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFQ90967.1 - 1e-06 28.8 0.0 1.5e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFQ90967.1 - 0.00017 21.2 0.0 0.00034 20.2 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFQ90967.1 - 0.00059 19.3 0.0 0.00088 18.7 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KFQ90967.1 - 0.00064 19.7 0.9 0.41 10.5 0.1 2.4 1 1 1 2 2 2 2 RsgA GTPase CPT PF07931.12 KFQ90967.1 - 0.0022 17.9 0.0 0.0039 17.1 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein FeoB_N PF02421.18 KFQ90967.1 - 0.14 11.7 0.5 3.1 7.3 0.5 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B CSN8_PSD8_EIF3K PF10075.9 KFQ90968.1 - 2.6e-36 124.7 0.0 3.5e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 KFQ90968.1 - 0.035 14.6 0.0 0.055 14.0 0.0 1.3 1 0 0 1 1 1 0 PCI domain AAA PF00004.29 KFQ90969.1 - 5.9e-17 62.3 0.0 1.5e-16 61.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IQ PF00612.27 KFQ90969.1 - 0.001 18.6 0.1 0.0029 17.3 0.1 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF3135 PF11333.8 KFQ90969.1 - 0.04 14.2 0.3 0.19 12.0 0.3 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) TsaE PF02367.17 KFQ90969.1 - 0.077 13.0 0.6 0.33 11.0 0.0 2.3 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ArfGap PF01412.18 KFQ90970.1 - 2.2e-40 137.4 0.1 5.2e-40 136.2 0.1 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ras PF00071.22 KFQ90970.1 - 3.1e-18 65.9 0.0 5.6e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Ras family Ank_2 PF12796.7 KFQ90970.1 - 3.3e-11 43.6 0.1 6.3e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) PH PF00169.29 KFQ90970.1 - 5.8e-11 42.8 3.2 9.5e-05 22.9 0.1 3.5 3 0 0 3 3 3 2 PH domain Ank PF00023.30 KFQ90970.1 - 8.7e-10 38.6 0.0 4.1e-06 27.0 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KFQ90970.1 - 3.8e-09 36.6 0.3 8.8e-09 35.5 0.3 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFQ90970.1 - 1.4e-07 31.9 0.1 1.6e-05 25.3 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ90970.1 - 1.6e-05 24.9 0.1 0.00049 20.3 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Roc PF08477.13 KFQ90970.1 - 0.00042 20.5 0.0 0.0023 18.1 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase PH_6 PF15406.6 KFQ90970.1 - 0.0038 17.5 0.3 0.0038 17.5 0.3 1.8 2 0 0 2 2 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFQ90970.1 - 0.024 15.1 7.9 0.44 11.0 0.3 3.4 4 0 0 4 4 3 0 Pleckstrin homology domain MAGI_u1 PF16663.5 KFQ90970.1 - 0.043 13.9 1.3 0.086 12.9 0.1 2.2 2 0 0 2 2 2 0 Unstructured region on MAGI PH_8 PF15409.6 KFQ90970.1 - 0.067 13.5 0.6 5.9 7.2 0.1 2.9 3 0 0 3 3 3 0 Pleckstrin homology domain LSDAT_euk PF18139.1 KFQ90971.1 - 2.9e-59 200.6 0.0 5.9e-59 199.6 0.0 1.5 1 0 0 1 1 1 1 SLOG in TRPM Ion_trans PF00520.31 KFQ90971.1 - 1e-14 54.4 21.2 1e-14 54.4 21.2 2.3 2 1 0 2 2 2 1 Ion transport protein LSDAT_prok PF18171.1 KFQ90971.1 - 1.6e-14 53.6 0.0 3.4e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote DUF2339 PF10101.9 KFQ90971.1 - 0.0079 14.8 1.9 0.0099 14.5 1.9 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) Spp-24 PF07448.11 KFQ90972.1 - 2.8e-21 75.4 0.2 4.7e-21 74.7 0.2 1.4 1 0 0 1 1 1 1 Secreted phosphoprotein 24 (Spp-24) cystatin-like domain Cathelicidins PF00666.17 KFQ90972.1 - 1.6e-08 34.8 0.0 2.1e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Cathelicidin Cystatin PF00031.21 KFQ90972.1 - 0.0069 16.6 0.0 0.01 16.1 0.0 1.2 1 0 0 1 1 1 1 Cystatin domain Arf PF00025.21 KFQ90973.1 - 3e-62 209.2 0.0 3.4e-62 209.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFQ90973.1 - 6.1e-16 58.7 0.0 8.1e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFQ90973.1 - 1.8e-15 56.9 0.0 1.9e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFQ90973.1 - 5.3e-11 42.3 0.0 8e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFQ90973.1 - 2.9e-08 33.3 0.1 1.4e-05 24.5 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KFQ90973.1 - 8.6e-08 32.3 0.0 1.2e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFQ90973.1 - 0.00041 20.0 0.0 0.0013 18.3 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFQ90973.1 - 0.0024 17.3 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region 6PF2K PF01591.18 KFQ90973.1 - 0.061 12.6 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase cobW PF02492.19 KFQ90973.1 - 0.14 11.8 0.0 1.1 8.8 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Scramblase PF03803.15 KFQ90974.1 - 0.032 13.5 0.0 0.032 13.5 0.0 1.0 1 0 0 1 1 1 0 Scramblase SH3_2 PF07653.17 KFQ90975.1 - 1.4e-22 79.1 0.1 5.1e-11 42.1 0.2 3.2 3 0 0 3 3 3 2 Variant SH3 domain SH3_9 PF14604.6 KFQ90975.1 - 1.7e-10 40.6 0.2 2.4e-09 36.9 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFQ90975.1 - 1.8e-10 40.3 0.6 2.6e-09 36.6 0.0 2.7 2 1 0 2 2 2 1 SH3 domain ZU5 PF00791.20 KFQ90975.1 - 6.3e-09 36.1 0.3 1.3e-08 35.1 0.3 1.5 1 0 0 1 1 1 1 ZU5 domain Death PF00531.22 KFQ90975.1 - 0.0019 18.3 2.1 0.79 9.9 0.1 3.5 2 1 1 3 3 3 2 Death domain IR1-M PF12185.8 KFQ90975.1 - 0.037 14.0 0.0 2.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain UDPGT PF00201.18 KFQ90976.1 - 4.4e-211 702.0 0.0 5.1e-211 701.8 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KFQ90976.1 - 8e-05 22.7 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Pro_3_hydrox_C PF05373.11 KFQ90976.1 - 0.13 12.3 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal Herpes_LMP2 PF07415.11 KFQ90976.1 - 0.15 10.8 1.6 0.21 10.3 1.6 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein UDPGT PF00201.18 KFQ90977.1 - 6.4e-46 157.2 0.0 7e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.18 KFQ90978.1 - 2.8e-42 145.2 0.0 3e-42 145.1 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.18 KFQ90979.1 - 3.1e-42 145.0 0.0 3.4e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase CRM1_C PF08767.11 KFQ90979.1 - 0.022 13.9 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 CRM1 C terminal UDPGT PF00201.18 KFQ90980.1 - 5.1e-44 150.9 0.1 5.6e-44 150.8 0.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.18 KFQ90981.1 - 1e-39 136.7 0.1 1.1e-39 136.6 0.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UCH PF00443.29 KFQ90982.1 - 3.8e-40 138.0 0.6 2.8e-34 118.8 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFQ90982.1 - 7.9e-19 68.4 0.1 1.5e-17 64.2 0.1 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase VWD PF00094.25 KFQ90983.1 - 3.7e-30 105.3 2.7 3.7e-30 105.3 2.7 2.0 2 0 0 2 2 2 1 von Willebrand factor type D domain C8 PF08742.11 KFQ90983.1 - 4.7e-19 68.6 16.5 4.7e-19 68.6 16.5 2.6 2 0 0 2 2 2 1 C8 domain TIL PF01826.17 KFQ90983.1 - 2.5e-05 24.4 4.5 2.5e-05 24.4 4.5 4.9 4 1 0 4 4 4 1 Trypsin Inhibitor like cysteine rich domain VWC PF00093.18 KFQ90983.1 - 0.00019 21.7 10.2 0.00019 21.7 10.2 4.7 3 2 1 4 4 4 1 von Willebrand factor type C domain Pacifastin_I PF05375.13 KFQ90983.1 - 0.003 17.3 11.4 0.003 17.3 11.4 3.5 2 1 0 2 2 2 1 Pacifastin inhibitor (LCMII) VWC PF00093.18 KFQ90984.1 - 1.2e-07 31.9 32.5 3.3e-05 24.1 15.0 3.8 3 1 0 3 3 3 2 von Willebrand factor type C domain Cys_knot PF00007.22 KFQ90984.1 - 9.6e-07 29.1 23.9 9.6e-07 29.1 23.9 3.2 2 1 0 2 2 2 1 Cystine-knot domain CUE PF02845.16 KFQ90985.1 - 1.2e-14 53.7 0.2 2.2e-14 52.8 0.2 1.5 1 0 0 1 1 1 1 CUE domain C2 PF00168.30 KFQ90985.1 - 5.1e-14 52.4 0.0 7.6e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 C2 domain UBA PF00627.31 KFQ90985.1 - 0.0004 20.2 0.1 0.00085 19.2 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain HTH_8 PF02954.19 KFQ90985.1 - 0.074 12.9 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Mob1_phocein PF03637.17 KFQ90988.1 - 3e-59 199.8 5.2 3.7e-59 199.5 5.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family DSPc PF00782.20 KFQ90989.1 - 3.4e-44 149.9 0.0 5e-44 149.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 KFQ90989.1 - 2e-11 44.4 0.0 4.7e-11 43.2 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.27 KFQ90989.1 - 0.0019 17.8 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KFQ90989.1 - 0.18 11.9 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate CD225 PF04505.12 KFQ90990.1 - 3.4e-21 75.1 0.7 5.3e-21 74.5 0.7 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein TMEM237 PF15383.6 KFQ90990.1 - 0.037 13.1 0.0 0.06 12.4 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 237 Internalin_N PF12354.8 KFQ90990.1 - 0.13 12.4 0.2 0.35 11.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal ScdA_N PF04405.14 KFQ90990.1 - 0.18 11.5 0.6 0.75 9.5 0.2 2.0 1 1 1 2 2 2 0 Domain of Unknown function (DUF542) Asp PF00026.23 KFQ90991.1 - 4.8e-128 427.0 0.0 5.5e-128 426.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFQ90991.1 - 5.2e-15 56.1 0.1 2.4e-12 47.5 0.1 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.12 KFQ90991.1 - 2.3e-07 30.6 0.3 5.4e-06 26.2 0.3 2.3 2 0 0 2 2 2 1 A1 Propeptide TAXi_C PF14541.6 KFQ90991.1 - 0.00012 21.9 0.0 0.00033 20.5 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KFQ90991.1 - 0.00014 22.5 0.3 2 9.1 0.1 3.3 2 1 0 2 2 2 2 Aspartyl protease 5-nucleotidase PF06189.12 KFQ90992.1 - 5e-91 304.3 0.0 4.4e-90 301.2 0.0 1.6 1 1 1 2 2 2 2 5'-nucleotidase Troponin PF00992.20 KFQ90993.1 - 4.2e-47 159.8 8.0 6.8e-47 159.1 8.0 1.3 1 0 0 1 1 1 1 Troponin DUF2408 PF10303.9 KFQ90993.1 - 0.0036 17.9 5.3 0.0094 16.5 5.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2408) DUF919 PF06034.11 KFQ90993.1 - 0.011 15.6 2.2 0.011 15.6 2.2 2.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Tup_N PF08581.10 KFQ90993.1 - 0.022 15.1 0.8 0.022 15.1 0.8 2.1 2 0 0 2 2 2 0 Tup N-terminal Sec2p PF06428.11 KFQ90993.1 - 0.031 14.3 1.5 0.031 14.3 1.5 3.1 3 2 0 3 3 3 0 GDP/GTP exchange factor Sec2p Helo_like_N PF17111.5 KFQ90993.1 - 0.056 12.8 3.5 0.13 11.6 3.5 1.7 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins KxDL PF10241.9 KFQ90993.1 - 0.086 13.1 2.6 0.16 12.2 0.4 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein YqgF PF14639.6 KFQ90993.1 - 0.24 11.2 1.9 0.58 9.9 0.2 1.9 1 1 1 2 2 2 0 Holliday-junction resolvase-like of SPT6 FAM167 PF11652.8 KFQ90993.1 - 0.3 11.6 4.2 0.25 11.9 0.5 2.3 1 1 0 2 2 2 0 FAM167 TFR_dimer PF04253.15 KFQ90993.1 - 0.4 10.8 2.2 0.39 10.8 0.2 2.1 2 1 0 2 2 2 0 Transferrin receptor-like dimerisation domain MPS2 PF17060.5 KFQ90993.1 - 0.41 9.9 6.9 0.027 13.8 2.1 1.4 2 0 0 2 2 2 0 Monopolar spindle protein 2 CENP-F_leu_zip PF10473.9 KFQ90993.1 - 0.93 9.5 15.2 0.066 13.2 7.4 2.2 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 KFQ90993.1 - 1 9.4 3.8 0.81 9.7 0.6 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 KFQ90993.1 - 4.4 6.1 4.2 3.8 6.3 3.1 1.5 1 1 0 1 1 1 0 LMBR1-like membrane protein APG6_N PF17675.1 KFQ90993.1 - 5.2 7.6 19.8 24 5.4 0.2 2.7 2 1 0 2 2 2 0 Apg6 coiled-coil region DUF4404 PF14357.6 KFQ90993.1 - 7.5 7.3 11.6 14 6.4 2.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Caldesmon PF02029.15 KFQ90994.1 - 8.4e-40 137.0 49.7 3.2e-28 98.8 26.1 2.8 1 1 2 3 3 3 3 Caldesmon DUF4643 PF15485.6 KFQ90995.1 - 3.5e-43 148.6 21.2 4.5e-43 148.3 21.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4643) Troponin PF00992.20 KFQ90997.1 - 6.2e-34 117.2 41.1 2e-31 109.0 34.7 2.1 1 1 1 2 2 2 2 Troponin Ndc1_Nup PF09531.10 KFQ90997.1 - 5.3 5.6 8.0 6.6 5.3 8.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hid1 PF12722.7 KFQ90997.1 - 9.2 4.3 12.7 11 4.0 12.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ribosomal_L23 PF00276.20 KFQ90998.1 - 4.2e-12 46.2 1.5 6.5e-12 45.7 1.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 RNA_pol_Rpc4 PF05132.14 KFQ90998.1 - 0.12 12.8 0.6 0.12 12.8 0.6 1.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 IGF2_C PF08365.11 KFQ90999.1 - 1.5e-29 101.8 3.5 2.7e-29 100.9 3.5 1.4 1 0 0 1 1 1 1 Insulin-like growth factor II E-peptide Insulin PF00049.18 KFQ90999.1 - 4.5e-13 50.0 8.1 1.7e-06 28.9 1.8 2.6 2 1 1 3 3 3 2 Insulin/IGF/Relaxin family Ins_beta PF03488.14 KFQ90999.1 - 0.28 11.2 2.6 9.7 6.3 0.1 2.3 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Insulin PF00049.18 KFQ91000.1 - 3.1e-24 85.8 1.4 3.8e-24 85.5 1.4 1.1 1 0 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.14 KFQ91000.1 - 0.019 15.0 5.3 0.45 10.6 0.2 2.2 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Biopterin_H PF00351.21 KFQ91001.1 - 2.6e-177 588.8 0.4 3.4e-177 588.4 0.4 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase TOH_N PF12549.8 KFQ91001.1 - 5.8e-22 76.9 1.3 4.5e-12 45.4 0.3 2.7 2 0 0 2 2 2 2 Tyrosine hydroxylase N terminal HSDR_N_2 PF13588.6 KFQ91001.1 - 0.054 13.5 0.0 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Tetraspanin PF00335.20 KFQ91002.1 - 9.7e-16 58.2 5.7 1.3e-15 57.8 5.7 1.1 1 0 0 1 1 1 1 Tetraspanin family Tetraspanin PF00335.20 KFQ91003.1 - 3e-40 138.3 7.1 3.7e-40 138.1 7.1 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF5638 PF18688.1 KFQ91003.1 - 0.14 12.5 0.1 6.2 7.2 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5638) DUF4282 PF14110.6 KFQ91003.1 - 8.8 7.1 12.6 12 6.7 4.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) TSSC4 PF15264.6 KFQ91004.1 - 1.2e-28 99.9 0.1 2.8e-28 98.7 0.1 1.7 1 0 0 1 1 1 1 Tumour suppressing sub-chromosomal transferable candidate 4 LSDAT_euk PF18139.1 KFQ91005.1 - 5.9e-50 170.1 0.0 1.3e-49 169.0 0.0 1.5 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 KFQ91005.1 - 9.9e-15 54.3 0.2 3e-14 52.7 0.0 1.8 2 0 0 2 2 2 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 KFQ91005.1 - 1.6e-10 40.6 23.8 9.4e-10 38.1 23.8 2.1 1 1 0 1 1 1 1 Ion transport protein Ion_trans PF00520.31 KFQ91006.1 - 1.6e-26 93.0 12.9 2.2e-26 92.6 12.9 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFQ91006.1 - 1e-11 44.6 5.7 1e-11 44.6 5.7 2.7 2 2 0 2 2 2 1 Ion channel Sensor PF13796.6 KFQ91006.1 - 0.026 14.6 1.6 0.026 14.6 1.6 2.4 2 1 0 2 2 2 0 Putative sensor CD225 PF04505.12 KFQ91006.1 - 0.64 10.2 0.0 0.64 10.2 0.0 3.2 3 0 0 3 3 3 0 Interferon-induced transmembrane protein DUF4462 PF14692.6 KFQ91007.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) MFS_1 PF07690.16 KFQ91008.1 - 1.6e-33 116.1 42.0 1.5e-30 106.4 32.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFQ91008.1 - 3.7e-05 22.7 24.7 0.011 14.6 10.7 3.0 1 1 1 3 3 3 2 MFS_1 like family MFS_3 PF05977.13 KFQ91008.1 - 0.00036 19.1 17.3 0.049 12.0 6.3 3.6 1 1 2 3 3 3 3 Transmembrane secretion effector PH_15 PF17339.2 KFQ91009.1 - 8.7e-12 44.9 0.0 1.2e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 PH domain PH PF00169.29 KFQ91009.1 - 5.9e-06 26.7 0.1 7.2e-06 26.5 0.1 1.1 1 0 0 1 1 1 1 PH domain NAP PF00956.18 KFQ91010.1 - 9.7e-106 352.9 5.6 9.7e-106 352.9 5.6 1.6 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Muted PF14942.6 KFQ91010.1 - 0.16 12.3 7.7 0.052 13.9 1.5 2.5 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein ING PF12998.7 KFQ91010.1 - 0.34 11.5 3.0 1.6 9.4 0.0 2.9 3 1 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding DUF3450 PF11932.8 KFQ91010.1 - 6.9 5.9 7.4 2.3 7.5 3.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) tRNA-synt_1e PF01406.19 KFQ91011.1 - 2e-128 428.0 0.2 2e-128 428.0 0.2 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KFQ91011.1 - 6.1e-07 28.5 1.7 0.00042 19.2 0.2 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KFQ91011.1 - 0.0026 16.1 0.9 0.011 14.0 0.0 2.4 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) Med7 PF05983.11 KFQ91011.1 - 0.04 14.0 6.0 0.098 12.7 6.0 1.7 1 0 0 1 1 1 0 MED7 protein WGG PF10273.9 KFQ91011.1 - 0.11 13.1 0.7 0.52 11.0 0.2 2.4 2 0 0 2 2 2 0 Pre-rRNA-processing protein TSR2 Senescence_reg PF04520.13 KFQ91011.1 - 0.45 11.3 4.5 0.13 13.0 1.2 1.9 2 0 0 2 2 2 0 Senescence regulator TNFR_c6 PF00020.18 KFQ91013.1 - 4.6e-11 42.9 5.6 4.6e-11 42.9 5.6 3.4 2 1 0 3 3 3 3 TNFR/NGFR cysteine-rich region PTP_tm PF18861.1 KFQ91014.1 - 1e-87 292.9 0.1 2.6e-87 291.6 0.1 1.7 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Y_phosphatase PF00102.27 KFQ91014.1 - 3.9e-83 278.6 0.6 6.8e-83 277.8 0.6 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase fn3 PF00041.21 KFQ91014.1 - 3.5e-32 110.6 17.6 1.4e-06 28.5 0.4 6.9 6 1 1 7 7 7 5 Fibronectin type III domain DUF2369 PF10179.9 KFQ91014.1 - 7.7e-09 35.8 1.2 2.9 8.4 0.0 4.8 4 0 0 4 4 4 4 Uncharacterised conserved protein (DUF2369) Interfer-bind PF09294.10 KFQ91014.1 - 2e-08 34.5 0.8 0.68 10.3 0.0 4.6 4 0 0 4 4 4 3 Interferon-alpha/beta receptor, fibronectin type III Citrate_ly_lig PF08218.11 KFQ91014.1 - 4e-05 23.4 2.6 8.1 6.1 0.0 5.1 5 1 1 6 6 6 1 Citrate lyase ligase C-terminal domain Pur_ac_phosph_N PF16656.5 KFQ91014.1 - 4.7e-05 23.9 17.1 0.56 10.8 0.2 5.6 5 1 0 6 6 5 3 Purple acid Phosphatase, N-terminal domain DUF4945 PF16303.5 KFQ91014.1 - 6.8e-05 22.8 0.1 10 6.1 0.0 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4945) CLP1_N PF16573.5 KFQ91014.1 - 0.00069 19.8 0.0 6.5 7.1 0.0 4.4 4 0 0 4 4 4 1 N-terminal beta-sandwich domain of polyadenylation factor PTPlike_phytase PF14566.6 KFQ91014.1 - 0.0062 16.7 0.0 0.03 14.4 0.0 2.2 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KFQ91014.1 - 0.0078 16.2 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KFQ91014.1 - 0.0084 15.9 0.0 0.024 14.4 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF2627 PF11118.8 KFQ91014.1 - 0.011 16.3 0.0 0.025 15.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) Syndecan PF01034.20 KFQ91014.1 - 0.022 14.7 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain DUF1297 PF06973.12 KFQ91014.1 - 0.028 14.0 0.1 10 5.6 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF1297) Y_phosphatase2 PF03162.13 KFQ91014.1 - 0.056 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF4381 PF14316.6 KFQ91014.1 - 0.15 12.3 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) VPDSG-CTERM PF18205.1 KFQ91014.1 - 0.61 10.0 1.7 1.1 9.2 1.7 1.4 1 0 0 1 1 1 0 VPDSG-CTERM motif Y_phosphatase PF00102.27 KFQ91015.1 - 2e-73 246.9 1.0 3.6e-73 246.0 1.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFQ91015.1 - 1.1e-06 28.5 0.0 3.6e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFQ91015.1 - 0.0012 18.9 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family YccF PF03733.13 KFQ91015.1 - 0.0059 17.3 0.7 0.024 15.3 0.7 2.1 1 0 0 1 1 1 1 Inner membrane component domain PTPlike_phytase PF14566.6 KFQ91015.1 - 0.089 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate CPSase_L_D2 PF02786.17 KFQ91015.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain YhhN PF07947.14 KFQ91016.1 - 1.6e-45 155.0 23.8 1.6e-45 155.0 23.8 1.3 1 1 0 1 1 1 1 YhhN family YtpI PF14007.6 KFQ91016.1 - 2.4 8.4 8.1 0.26 11.4 0.3 2.9 2 1 0 2 2 2 0 YtpI-like protein SPT2 PF08243.11 KFQ91017.1 - 1.1e-21 77.4 24.6 1.1e-21 77.4 24.6 3.8 5 0 0 5 5 5 1 SPT2 chromatin protein UEV PF05743.13 KFQ91018.1 - 2.5e-42 143.6 0.2 4e-42 142.9 0.2 1.3 1 0 0 1 1 1 1 UEV domain Ldh_1_N PF00056.23 KFQ91018.1 - 8e-23 81.1 0.5 1.5e-22 80.2 0.5 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KFQ91018.1 - 6.4e-12 45.7 0.0 1.1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3HCDH_N PF02737.18 KFQ91018.1 - 0.072 13.0 0.2 0.14 12.1 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UEV PF05743.13 KFQ91019.1 - 6.5e-48 161.6 1.3 6.8e-47 158.3 0.3 2.2 2 0 0 2 2 2 1 UEV domain Vps23_core PF09454.10 KFQ91019.1 - 3.8e-28 97.2 0.1 6.7e-28 96.4 0.1 1.4 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.26 KFQ91019.1 - 0.00012 21.7 0.3 0.00012 21.7 0.3 2.2 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme DUF3450 PF11932.8 KFQ91019.1 - 0.00068 19.0 8.4 0.0012 18.2 8.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Macoilin PF09726.9 KFQ91019.1 - 0.0068 15.0 2.4 0.0091 14.6 2.4 1.1 1 0 0 1 1 1 1 Macoilin family APG6_N PF17675.1 KFQ91019.1 - 0.019 15.5 11.8 0.019 15.5 11.8 1.6 2 0 0 2 2 1 0 Apg6 coiled-coil region GPS2_interact PF15784.5 KFQ91019.1 - 0.026 15.0 9.0 0.096 13.1 9.0 1.9 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF1640 PF07798.11 KFQ91019.1 - 0.027 14.5 7.1 0.027 14.5 7.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) ERM PF00769.19 KFQ91019.1 - 0.052 13.3 13.9 0.092 12.5 13.9 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Fzo_mitofusin PF04799.13 KFQ91019.1 - 0.061 12.9 4.5 0.12 11.9 4.5 1.4 1 0 0 1 1 1 0 fzo-like conserved region Exonuc_VII_L PF02601.15 KFQ91019.1 - 0.076 12.6 1.6 0.097 12.2 1.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 KFQ91019.1 - 0.082 11.5 5.0 0.11 11.0 5.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Prominin PF05478.11 KFQ91019.1 - 0.11 10.5 2.1 0.15 10.0 2.1 1.1 1 0 0 1 1 1 0 Prominin SlyX PF04102.12 KFQ91019.1 - 0.15 12.7 12.7 0.14 12.8 3.4 3.2 2 1 1 3 3 3 0 SlyX DUF3552 PF12072.8 KFQ91019.1 - 0.17 11.3 10.2 0.26 10.7 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Spc7 PF08317.11 KFQ91019.1 - 0.18 10.7 10.4 0.26 10.1 10.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3492 PF11997.8 KFQ91019.1 - 0.31 10.8 0.7 0.48 10.1 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) DUF3782 PF12644.7 KFQ91019.1 - 0.35 11.0 5.9 5 7.4 0.0 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3782) TMPIT PF07851.13 KFQ91019.1 - 0.46 9.7 3.6 0.65 9.2 3.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein Spc24 PF08286.11 KFQ91019.1 - 0.51 10.6 12.7 0.81 10.0 5.2 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Fib_alpha PF08702.10 KFQ91019.1 - 0.56 10.4 5.0 1 9.5 5.0 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KFQ91019.1 - 0.6 10.2 4.8 1.1 9.3 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KFQ91019.1 - 0.61 10.5 11.8 1 9.8 0.8 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Nsp1_C PF05064.13 KFQ91019.1 - 0.96 9.3 8.1 0.79 9.5 5.5 2.1 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF724 PF05266.14 KFQ91019.1 - 0.98 9.2 9.5 1.7 8.4 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 KFQ91019.1 - 1 7.2 3.0 1.3 6.8 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spore_III_AB PF09548.10 KFQ91019.1 - 1.4 9.0 4.9 2.1 8.4 4.9 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) NPV_P10 PF05531.12 KFQ91019.1 - 1.6 9.3 5.7 4.1 7.9 3.7 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein PCRF PF03462.18 KFQ91019.1 - 2.2 8.1 6.4 4.1 7.2 6.4 1.4 1 0 0 1 1 1 0 PCRF domain Atg14 PF10186.9 KFQ91019.1 - 2.4 7.1 5.6 4 6.4 5.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DivIC PF04977.15 KFQ91019.1 - 2.7 7.8 14.2 1.9 8.3 2.2 2.6 1 1 1 2 2 2 0 Septum formation initiator DUF4140 PF13600.6 KFQ91019.1 - 3.2 8.3 7.9 29 5.2 7.3 2.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Laminin_II PF06009.12 KFQ91019.1 - 3.6 7.6 8.3 9.9 6.2 5.6 2.2 2 0 0 2 2 2 0 Laminin Domain II Prefoldin PF02996.17 KFQ91019.1 - 5.1 7.0 10.3 5 7.1 2.3 2.3 1 1 1 2 2 2 0 Prefoldin subunit BRE1 PF08647.11 KFQ91019.1 - 5.7 7.1 17.7 3.1 7.9 13.9 2.0 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Prefoldin_2 PF01920.20 KFQ91019.1 - 6.7 6.7 15.0 5.5 7.0 2.8 2.4 1 1 1 2 2 2 0 Prefoldin subunit TMF_DNA_bd PF12329.8 KFQ91019.1 - 7.8 6.6 18.1 9.9 6.2 15.8 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Ldh_1_N PF00056.23 KFQ91020.1 - 1.6e-47 161.1 0.2 2.3e-47 160.6 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KFQ91020.1 - 1.3e-21 77.3 0.0 4.8e-21 75.4 0.0 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 KFQ91020.1 - 0.0056 16.3 0.7 0.037 13.6 0.0 2.4 3 0 0 3 3 3 1 Family 4 glycosyl hydrolase PH_TFIIH PF08567.11 KFQ91021.1 - 4.8e-25 87.7 0.0 9.2e-25 86.8 0.0 1.4 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.17 KFQ91021.1 - 1.1e-22 79.7 5.1 1.2e-16 60.5 0.0 3.4 4 0 0 4 4 4 2 BSD domain SAA PF00277.18 KFQ91022.1 - 1.2e-46 157.4 7.8 1.3e-46 157.3 7.8 1.0 1 0 0 1 1 1 1 Serum amyloid A protein Biopterin_H PF00351.21 KFQ91024.1 - 3.1e-177 588.6 0.1 3.9e-177 588.2 0.1 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 KFQ91024.1 - 1.5e-06 27.8 0.1 3.3e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 ACT domain DUF5370 PF17340.2 KFQ91024.1 - 0.032 14.1 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5370) Seryl_tRNA_N PF02403.22 KFQ91024.1 - 0.11 12.8 0.7 18 5.6 0.0 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ACT_4 PF13291.6 KFQ91024.1 - 0.14 12.8 0.4 0.14 12.8 0.4 1.9 2 0 0 2 2 2 0 ACT domain RCC1 PF00415.18 KFQ91025.1 - 5.6e-53 177.4 19.1 7.2e-11 42.5 0.2 6.7 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFQ91025.1 - 6e-33 112.0 38.3 6e-09 35.5 0.5 6.9 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Ion_trans PF00520.31 KFQ91026.1 - 8.2e-45 152.9 12.8 1e-44 152.6 12.8 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFQ91026.1 - 6.8e-28 96.9 0.0 1.7e-27 95.6 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFQ91026.1 - 2.7e-11 43.3 2.6 2.7e-11 43.3 2.6 2.5 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.5 KFQ91026.1 - 0.0029 17.7 0.0 0.0068 16.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Basic PF01586.16 KFQ91027.1 - 1.6e-29 102.9 3.0 1.8e-29 102.7 1.3 2.0 2 0 0 2 2 2 1 Myogenic Basic domain Myf5 PF12232.8 KFQ91027.1 - 1.2e-24 86.8 11.7 1.2e-24 86.8 11.7 1.9 2 0 0 2 2 2 1 Myogenic determination factor 5 HLH PF00010.26 KFQ91027.1 - 5e-14 52.0 3.6 1e-13 51.0 3.6 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ferritin PF00210.24 KFQ91029.1 - 2.3e-13 50.3 0.1 3.4e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 KFQ91029.1 - 0.095 13.1 0.4 0.16 12.4 0.4 1.3 1 0 0 1 1 1 0 Rubrerythrin VWD PF00094.25 KFQ91030.1 - 1.9e-78 262.2 9.6 7.7e-35 120.5 0.3 3.7 3 0 0 3 3 3 3 von Willebrand factor type D domain C8 PF08742.11 KFQ91030.1 - 1.5e-41 140.6 58.3 5e-16 58.9 5.9 9.6 8 0 0 8 8 8 4 C8 domain TIL PF01826.17 KFQ91030.1 - 7.7e-14 51.7 82.5 2.5e-10 40.4 20.8 16.8 15 2 1 16 16 16 5 Trypsin Inhibitor like cysteine rich domain AbfB PF05270.13 KFQ91030.1 - 1.5e-07 31.5 0.1 3.3e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain VWC PF00093.18 KFQ91030.1 - 0.0017 18.6 3.0 0.0017 18.6 3.0 18.1 12 3 7 19 19 19 4 von Willebrand factor type C domain IL33 PF15095.6 KFQ91030.1 - 0.0059 16.1 0.2 0.025 14.0 0.2 2.1 1 1 0 1 1 1 1 Interleukin 33 ABC_membrane PF00664.23 KFQ91031.1 - 9.3e-76 255.1 38.4 2.3e-41 142.3 4.9 2.8 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFQ91031.1 - 3e-50 170.3 2.9 2.2e-24 86.5 0.0 3.7 4 0 0 4 4 4 2 ABC transporter SMC_N PF02463.19 KFQ91031.1 - 6.5e-09 35.5 3.1 0.0082 15.6 0.6 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFQ91031.1 - 0.00028 20.8 2.7 1.2 8.9 0.1 3.9 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFQ91031.1 - 0.00063 19.4 1.0 0.34 10.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KFQ91031.1 - 0.0024 16.8 1.0 0.12 11.1 0.0 3.0 3 1 0 3 3 3 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 KFQ91031.1 - 0.0025 17.4 0.0 0.13 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KFQ91031.1 - 0.0026 17.7 0.0 0.19 11.6 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KFQ91031.1 - 0.011 15.8 0.2 3.7 7.7 0.1 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.6 KFQ91031.1 - 0.035 14.4 0.9 6.4 7.0 0.1 2.9 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 KFQ91031.1 - 0.054 12.8 0.2 9 5.6 0.0 2.5 2 0 0 2 2 2 0 KaiC AAA_15 PF13175.6 KFQ91031.1 - 0.07 12.8 0.4 3.4 7.3 0.1 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 KFQ91031.1 - 0.076 12.5 0.1 5.7 6.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_23 PF13476.6 KFQ91031.1 - 0.091 13.3 7.8 7.9 6.9 4.3 3.0 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KFQ91031.1 - 0.099 12.4 0.2 0.47 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 KFQ91031.1 - 0.14 11.8 0.0 2.8 7.5 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.12 KFQ91031.1 - 0.14 11.4 0.0 0.94 8.7 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.23 KFQ91031.1 - 8.5 6.4 5.9 8.3 6.4 0.0 2.9 3 0 0 3 3 3 0 Dynamin family IRK_C PF17655.1 KFQ91032.1 - 3.2e-69 232.0 0.0 4.1e-69 231.6 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFQ91032.1 - 8.5e-57 190.9 0.5 1.3e-56 190.3 0.5 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain EI24 PF07264.11 KFQ91032.1 - 0.029 14.6 2.0 0.049 13.9 2.0 1.3 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Cupin_2 PF07883.11 KFQ91032.1 - 0.15 11.8 0.1 0.31 10.8 0.1 1.5 1 0 0 1 1 1 0 Cupin domain Ion_trans_2 PF07885.16 KFQ91032.1 - 1.1 9.3 7.8 0.072 13.1 1.7 2.0 2 0 0 2 2 2 0 Ion channel EF-hand_7 PF13499.6 KFQ91033.1 - 2e-11 44.2 3.4 2e-11 44.2 3.4 4.3 3 2 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KFQ91033.1 - 8.9e-09 34.3 5.2 0.00021 20.6 0.4 3.8 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 KFQ91033.1 - 2.4e-07 30.1 3.1 1.3e-05 24.7 0.2 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 KFQ91033.1 - 0.00035 19.9 3.6 0.0096 15.4 0.4 4.3 4 0 0 4 4 4 1 EF hand Histone_HNS PF00816.21 KFQ91033.1 - 0.043 14.6 0.4 0.043 14.6 0.4 3.6 2 1 0 3 3 3 0 H-NS histone family WXG100 PF06013.12 KFQ91033.1 - 0.045 14.0 7.2 0.13 12.5 7.2 1.9 1 0 0 1 1 1 0 Proteins of 100 residues with WXG EF-hand_8 PF13833.6 KFQ91033.1 - 0.07 13.0 1.8 2.9 7.8 0.0 3.6 3 0 0 3 3 3 0 EF-hand domain pair FUSC-like PF12805.7 KFQ91033.1 - 0.87 8.6 6.9 2.1 7.4 6.9 1.6 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS MctB PF11382.8 KFQ91033.1 - 2.6 7.7 7.7 5.1 6.7 7.7 1.4 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB MMTV_SAg PF01054.17 KFQ91033.1 - 4 6.9 6.3 0.81 9.2 0.2 2.3 2 0 0 2 2 2 0 Mouse mammary tumour virus superantigen Ribosomal_S13_N PF08069.12 KFQ91034.1 - 7.1e-26 90.0 0.1 1.3e-25 89.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KFQ91034.1 - 4.2e-15 55.7 1.2 7.2e-15 55.0 1.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 KFQ91034.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain HMG_box PF00505.19 KFQ91035.1 - 1.5e-22 79.8 4.5 5.5e-22 78.0 4.5 2.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFQ91035.1 - 2e-09 37.9 1.1 2e-09 37.9 1.1 3.4 3 0 0 3 3 3 1 HMG-box domain MPS2 PF17060.5 KFQ91035.1 - 2.5 7.3 17.1 0.11 11.7 11.3 1.6 2 0 0 2 2 2 0 Monopolar spindle protein 2 DivIVA PF05103.13 KFQ91035.1 - 9.8 6.3 18.7 11 6.1 13.6 2.4 2 0 0 2 2 2 0 DivIVA protein INSC_LBD PF16748.5 KFQ91037.1 - 9.1e-28 95.5 5.0 2e-27 94.3 5.0 1.5 1 0 0 1 1 1 1 Inscuteable LGN-binding domain Arm PF00514.23 KFQ91037.1 - 0.0047 16.9 0.3 0.0047 16.9 0.3 5.2 5 1 0 5 5 5 2 Armadillo/beta-catenin-like repeat SPOB_ab PF14682.6 KFQ91037.1 - 2 8.5 7.1 2.5 8.2 2.6 2.7 2 1 1 3 3 3 0 Sporulation initiation phospho-transferase B, C-terminal Calc_CGRP_IAPP PF00214.19 KFQ91038.1 - 2.2e-43 147.4 0.2 2.5e-43 147.3 0.2 1.0 1 0 0 1 1 1 1 Calcitonin / CGRP / IAPP family TA_inhibitor PF17574.2 KFQ91038.1 - 0.069 13.2 0.1 0.14 12.2 0.0 1.4 1 1 0 1 1 1 0 Inhibitor of toxin/antitoxin system (Gp4.5) p450 PF00067.22 KFQ91039.1 - 2.6e-117 392.4 0.0 2.9e-117 392.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Proteasome PF00227.26 KFQ91040.1 - 2.8e-51 173.7 0.0 3.5e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFQ91040.1 - 2e-13 49.7 0.0 3.5e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Adaptin_N PF01602.20 KFQ91041.1 - 1.6e-122 409.8 8.7 2.4e-122 409.2 8.7 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 KFQ91041.1 - 7.4e-61 204.2 0.3 1.6e-60 203.1 0.3 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 KFQ91041.1 - 2.9e-60 201.9 0.1 1.6e-59 199.5 0.0 2.2 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 KFQ91041.1 - 4.1e-08 33.4 12.3 3.2e-05 24.0 0.1 4.2 2 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFQ91041.1 - 8.7e-08 31.8 0.2 0.035 14.4 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 KFQ91041.1 - 1.2e-07 32.0 4.0 0.033 14.6 0.0 6.0 5 2 3 8 8 8 3 HEAT repeats HEAT_EZ PF13513.6 KFQ91041.1 - 5.2e-06 26.8 0.4 1.1 9.8 0.0 5.1 5 0 0 5 5 5 2 HEAT-like repeat Arm PF00514.23 KFQ91041.1 - 0.00023 21.1 0.1 1.7 8.8 0.0 4.1 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat MMS19_N PF14500.6 KFQ91041.1 - 0.00029 20.5 2.0 0.0053 16.4 0.0 3.4 2 1 2 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II DUF5578 PF17741.1 KFQ91041.1 - 0.0068 15.9 4.9 0.95 8.8 0.2 3.3 1 1 2 3 3 3 2 Family of unknown function (DUF5578) Ras PF00071.22 KFQ91042.1 - 1.9e-48 164.1 0.3 2.2e-48 163.9 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ91042.1 - 4.6e-12 46.2 0.0 1.6e-11 44.4 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KFQ91042.1 - 2.2e-06 27.3 0.0 2.7e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KFQ91042.1 - 7.8e-06 25.4 0.1 9.3e-06 25.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 KFQ91042.1 - 0.0087 15.9 0.1 0.01 15.6 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein WD40 PF00400.32 KFQ91043.1 - 1.1e-18 67.2 10.6 1.9e-05 25.3 0.1 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ91043.1 - 3.5e-07 30.4 0.0 3.2 8.1 0.0 4.8 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 KFQ91043.1 - 6.4e-05 22.8 1.4 0.00011 22.1 0.7 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFQ91043.1 - 0.0035 17.2 0.3 0.008 16.0 0.3 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 KFQ91043.1 - 0.019 13.7 0.0 1.9 7.1 0.0 2.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 WD40_like PF17005.5 KFQ91043.1 - 0.028 13.8 0.0 0.049 12.9 0.0 1.5 1 0 0 1 1 1 0 WD40-like domain ZapB PF06005.12 KFQ91043.1 - 3.6 8.1 5.0 4.8 7.7 2.2 2.4 2 0 0 2 2 2 0 Cell division protein ZapB p450 PF00067.22 KFQ91044.1 - 4.5e-131 437.8 0.2 5.1e-131 437.6 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 RhoGAP PF00620.27 KFQ91045.1 - 4.3e-46 156.5 0.1 2.8e-45 153.8 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain BAR PF03114.18 KFQ91045.1 - 1.4e-43 149.3 8.5 1e-37 130.0 2.8 2.5 1 1 1 2 2 2 2 BAR domain DUF773 PF05600.12 KFQ91045.1 - 0.02 13.6 0.6 0.04 12.7 0.6 1.4 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 UCH PF00443.29 KFQ91046.1 - 5e-11 42.6 0.0 6.3e-11 42.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-MIZ PF02891.20 KFQ91046.1 - 0.55 10.0 4.4 0.99 9.2 4.4 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger WD40 PF00400.32 KFQ91047.1 - 2.1e-32 110.6 27.1 6.7e-05 23.6 0.1 11.1 11 1 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ91047.1 - 4.4e-08 33.3 1.2 1.1 9.6 0.0 6.4 2 2 3 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFQ91047.1 - 1.1e-07 31.5 3.1 0.084 12.2 0.1 4.4 2 1 1 4 4 4 3 WD40-like domain PQQ_2 PF13360.6 KFQ91047.1 - 0.005 16.5 0.0 3.2 7.3 0.1 3.6 2 1 0 3 3 3 1 PQQ-like domain Kelch_6 PF13964.6 KFQ91047.1 - 0.023 15.0 1.0 12 6.3 0.0 4.2 4 0 0 4 4 4 0 Kelch motif Nucleoporin_N PF08801.11 KFQ91047.1 - 0.036 12.8 1.3 15 4.1 0.1 4.3 3 2 3 6 6 6 0 Nup133 N terminal like PQQ_3 PF13570.6 KFQ91047.1 - 0.041 14.4 10.0 16 6.1 0.2 6.5 6 1 2 8 8 8 0 PQQ-like domain eIF2A PF08662.11 KFQ91047.1 - 0.13 12.1 0.0 4.1 7.2 0.0 2.9 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A TLD PF07534.16 KFQ91048.1 - 6.6e-28 97.7 0.0 1e-14 54.9 0.0 2.5 2 0 0 2 2 2 2 TLD RabGAP-TBC PF00566.18 KFQ91048.1 - 2.3e-24 86.3 0.5 4.1e-24 85.4 0.5 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SNARE PF05739.19 KFQ91049.1 - 0.01 15.8 0.2 0.03 14.3 0.2 1.9 1 0 0 1 1 1 0 SNARE domain Baculo_PEP_C PF04513.12 KFQ91049.1 - 0.023 14.8 5.8 0.12 12.4 0.3 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 KFQ91049.1 - 0.041 14.0 7.4 0.22 11.6 0.3 3.1 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Seryl_tRNA_N PF02403.22 KFQ91049.1 - 0.081 13.2 0.3 0.081 13.2 0.3 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FUSC-like PF12805.7 KFQ91049.1 - 1.5 7.8 5.3 0.51 9.4 1.3 2.0 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS DUF1664 PF07889.12 KFQ91049.1 - 2.2 8.3 7.4 3.1 7.9 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 KFQ91049.1 - 4.1 7.9 10.3 4.5 7.8 2.7 2.8 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4559 PF15112.6 KFQ91049.1 - 5.9 6.5 9.1 9.6 5.8 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) TMPIT PF07851.13 KFQ91049.1 - 10 5.3 8.1 4.6 6.4 0.9 2.0 2 0 0 2 2 2 0 TMPIT-like protein Laminin_N PF00055.17 KFQ91050.1 - 2.2e-87 292.5 0.3 2.2e-87 292.5 0.3 3.9 3 1 2 5 5 5 1 Laminin N-terminal (Domain VI) NTR PF01759.21 KFQ91050.1 - 1.8e-31 108.1 1.0 3.5e-31 107.2 1.0 1.5 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Laminin_EGF PF00053.24 KFQ91050.1 - 1.3e-25 89.2 64.9 2.6e-10 40.3 14.6 4.5 5 0 0 5 5 5 3 Laminin EGF domain PI3K_1B_p101 PF10486.9 KFQ91051.1 - 3.8e-64 216.9 0.6 4.2e-64 216.7 0.6 1.0 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit MFS_1_like PF12832.7 KFQ91052.1 - 2.4e-49 168.2 0.9 3.3e-49 167.8 0.9 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFQ91052.1 - 8.5e-10 38.1 17.9 8.5e-10 38.1 17.9 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF3585 PF12130.8 KFQ91053.1 - 3.3e-22 79.1 15.1 5.5e-22 78.4 15.1 1.3 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain Hep_59 PF07052.11 KFQ91053.1 - 0.0065 17.2 3.2 0.12 13.2 0.2 2.2 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 NEXCaM_BD PF16644.5 KFQ91053.1 - 0.026 14.8 1.2 0.026 14.8 1.2 2.1 2 0 0 2 2 2 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin MIEAP PF16026.5 KFQ91053.1 - 0.043 14.0 1.5 0.05 13.8 1.5 1.2 1 0 0 1 1 1 0 Mitochondria-eating protein Histone_HNS PF00816.21 KFQ91053.1 - 0.081 13.8 3.9 0.14 13.0 3.9 1.5 1 0 0 1 1 1 0 H-NS histone family DUF1027 PF06265.11 KFQ91053.1 - 0.11 12.4 1.3 0.29 11.1 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1027) FlxA PF14282.6 KFQ91053.1 - 0.42 10.6 10.2 0.067 13.2 5.8 1.8 2 0 0 2 2 2 0 FlxA-like protein MRPL52 PF18699.1 KFQ91053.1 - 3.5 7.9 10.7 0.54 10.5 5.1 2.1 1 1 1 2 2 2 0 Mitoribosomal protein mL52 DUF4200 PF13863.6 KFQ91054.1 - 3e-22 79.3 37.3 7.7e-22 77.9 26.6 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4200) Myosin_tail_1 PF01576.19 KFQ91055.1 - 0 1613.8 304.4 0 1613.6 304.4 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_head PF00063.21 KFQ91055.1 - 0 1023.0 0.9 0 1023.0 0.9 3.9 3 1 0 4 4 4 1 Myosin head (motor domain) Myosin_N PF02736.19 KFQ91055.1 - 8.8e-13 47.9 0.2 2.4e-12 46.4 0.2 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain ADIP PF11559.8 KFQ91055.1 - 3e-05 24.1 20.5 3e-05 24.1 20.5 13.3 1 1 12 13 13 13 6 Afadin- and alpha -actinin-Binding IQ PF00612.27 KFQ91055.1 - 8.5e-05 22.0 0.1 0.00026 20.5 0.1 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif CC2-LZ PF16516.5 KFQ91055.1 - 0.008 16.5 17.0 0.008 16.5 17.0 16.3 4 2 11 15 15 15 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator AAA_22 PF13401.6 KFQ91055.1 - 0.079 13.2 0.0 0.079 13.2 0.0 6.6 5 2 2 7 7 7 0 AAA domain HEAT_UF PF18817.1 KFQ91055.1 - 0.1 12.9 0.4 12 6.3 0.2 3.2 2 0 0 2 2 2 0 Repeat of uncharacterized protein PH0542 NUDE_C PF04880.13 KFQ91056.1 - 3.2e-46 158.0 13.3 6.8e-46 157.0 0.7 2.4 2 1 0 2 2 2 1 NUDE protein, C-terminal conserved region PRKG1_interact PF15898.5 KFQ91056.1 - 0.0053 17.6 8.0 0.0053 17.6 8.0 2.9 1 1 2 3 3 3 2 cGMP-dependent protein kinase interacting domain HALZ PF02183.18 KFQ91056.1 - 0.021 15.1 2.6 0.021 15.1 2.6 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF5576 PF17739.1 KFQ91056.1 - 0.029 14.5 0.3 2.7 8.1 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5576) Rootletin PF15035.6 KFQ91056.1 - 0.073 13.1 31.7 0.18 11.8 12.4 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF1664 PF07889.12 KFQ91056.1 - 0.13 12.3 9.8 0.051 13.6 4.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 KFQ91056.1 - 0.15 11.5 24.2 0.26 10.7 24.2 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 ATG16 PF08614.11 KFQ91056.1 - 0.25 11.6 35.8 1.5 9.0 9.1 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HAD_SAK_1 PF10307.9 KFQ91056.1 - 0.26 11.1 7.0 1.5 8.6 6.8 1.9 1 1 1 2 2 2 0 HAD domain family 1 in Swiss Army Knife RNA repair proteins TPR_MLP1_2 PF07926.12 KFQ91056.1 - 0.36 10.9 35.2 0.078 13.0 10.0 3.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein KxDL PF10241.9 KFQ91056.1 - 1.3 9.4 14.6 0.33 11.3 5.9 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein FlaC_arch PF05377.11 KFQ91056.1 - 1.7 9.1 8.5 3.7 8.0 1.0 3.9 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) Fzo_mitofusin PF04799.13 KFQ91056.1 - 2.1 7.9 15.0 0.21 11.1 5.6 2.8 1 1 2 3 3 3 0 fzo-like conserved region BST2 PF16716.5 KFQ91056.1 - 3 8.5 24.8 0.57 10.8 12.4 3.1 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 YabA PF06156.13 KFQ91056.1 - 3.5 8.3 20.8 5.5 7.7 7.0 3.3 1 1 2 3 3 3 0 Initiation control protein YabA DUF5595 PF18077.1 KFQ91056.1 - 4.4 7.4 18.3 0.13 12.4 3.8 3.5 2 2 2 4 4 4 0 Domain of unknown function (DUF5595) YtxH PF12732.7 KFQ91056.1 - 4.6 7.8 5.7 5.9 7.5 1.2 3.0 2 1 0 2 2 2 0 YtxH-like protein CENP-F_leu_zip PF10473.9 KFQ91056.1 - 7.7 6.5 31.2 1.6 8.7 22.9 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lectin_N PF03954.14 KFQ91056.1 - 9.4 6.0 11.8 1.4 8.7 3.8 3.1 2 1 2 4 4 4 0 Hepatic lectin, N-terminal domain zf-RING_UBOX PF13445.6 KFQ91057.1 - 2.3e-09 37.1 6.4 2.3e-09 37.1 6.4 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFQ91057.1 - 3.8e-08 33.5 10.8 1.2e-07 31.9 10.8 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFQ91057.1 - 1.2e-06 28.4 10.7 2.7e-06 27.2 10.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFQ91057.1 - 6.7e-05 22.7 11.2 0.00014 21.6 11.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KFQ91057.1 - 0.00094 19.3 5.9 0.00094 19.3 5.9 1.7 2 0 0 2 2 2 1 FYVE zinc finger zf-C3HC4_2 PF13923.6 KFQ91057.1 - 0.0016 18.2 14.7 0.014 15.3 14.7 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KFQ91057.1 - 0.0093 15.7 7.6 0.019 14.7 7.6 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KFQ91057.1 - 0.02 14.6 8.3 0.02 14.6 8.3 2.1 2 0 0 2 2 2 0 RING-like zinc finger GAGA PF09237.11 KFQ91057.1 - 0.088 12.6 2.3 2 8.3 0.1 2.4 2 0 0 2 2 2 0 GAGA factor zf-4CXXC_R1 PF10497.9 KFQ91057.1 - 0.1 12.8 3.5 0.2 11.9 3.5 1.4 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Prok-RING_4 PF14447.6 KFQ91057.1 - 0.1 12.5 14.5 3 7.8 14.2 2.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 FYVE_2 PF02318.16 KFQ91057.1 - 0.2 11.9 5.6 0.14 12.3 3.6 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger zf-C3HC4_4 PF15227.6 KFQ91057.1 - 0.46 10.7 16.0 0.35 11.0 12.5 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING PIRT PF15099.6 KFQ91058.1 - 1.2e-70 235.1 2.7 1.4e-70 235.0 2.7 1.0 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family TMEM100 PF16311.5 KFQ91058.1 - 0.00018 21.1 0.2 0.00021 20.9 0.2 1.1 1 0 0 1 1 1 1 Transmembrane protein 100 L_HMGIC_fpl PF10242.9 KFQ91058.1 - 0.00057 20.1 0.2 0.00065 19.9 0.2 1.1 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Phage_holin_3_6 PF07332.11 KFQ91058.1 - 0.016 15.2 0.1 0.023 14.7 0.1 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III YajC PF02699.15 KFQ91058.1 - 0.031 14.1 0.3 0.031 14.1 0.3 1.5 2 0 0 2 2 2 0 Preprotein translocase subunit 7TM_GPCR_Srz PF10325.9 KFQ91058.1 - 0.035 13.4 1.3 0.038 13.3 1.3 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz SdpI PF13630.6 KFQ91058.1 - 0.056 13.6 2.9 0.34 11.1 2.9 2.0 1 1 0 1 1 1 0 SdpI/YhfL protein family Ferric_reduct PF01794.19 KFQ91058.1 - 0.066 13.3 0.4 0.13 12.4 0.1 1.5 1 1 0 1 1 1 0 Ferric reductase like transmembrane component Neurensin PF14927.6 KFQ91058.1 - 0.083 12.6 2.4 1.3 8.8 0.1 2.1 1 1 0 2 2 2 0 Neurensin DUF2663 PF10864.8 KFQ91058.1 - 0.1 13.0 0.1 0.15 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) EphA2_TM PF14575.6 KFQ91058.1 - 0.13 13.2 3.9 4.7 8.2 3.9 2.2 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3040 PF11239.8 KFQ91058.1 - 2.8 8.3 4.4 48 4.3 4.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) MT PF12777.7 KFQ91060.1 - 8.1e-198 656.4 14.3 1.3e-197 655.7 14.3 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor DHC_N1 PF08385.12 KFQ91060.1 - 8.5e-171 569.4 6.8 8.5e-171 569.4 6.8 3.4 3 1 1 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 KFQ91060.1 - 1.3e-154 514.0 0.0 1.1e-153 511.0 0.0 2.5 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KFQ91060.1 - 1.3e-112 376.9 5.4 1.3e-112 376.9 5.4 4.7 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 KFQ91060.1 - 9.4e-98 327.2 0.4 3.1e-97 325.5 0.4 2.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 KFQ91060.1 - 9.7e-98 326.6 0.0 3.8e-97 324.7 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KFQ91060.1 - 2.7e-82 275.2 0.1 2.7e-82 275.2 0.1 2.4 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 KFQ91060.1 - 1.2e-78 262.8 0.0 4.5e-71 238.1 0.0 3.7 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KFQ91060.1 - 2.9e-54 183.3 0.0 8.7e-54 181.7 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KFQ91060.1 - 1.6e-48 163.0 0.4 1.6e-48 163.0 0.4 4.5 5 0 0 5 5 4 1 AAA+ lid domain Dynein_heavy PF03028.15 KFQ91060.1 - 9.7e-40 135.4 0.0 2.5e-38 130.8 0.0 3.2 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 KFQ91060.1 - 1.2e-27 96.6 0.5 6.2e-27 94.2 0.5 2.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KFQ91060.1 - 6.4e-27 94.2 0.0 2.9e-13 50.0 0.0 6.5 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFQ91060.1 - 2e-07 31.6 3.6 0.049 14.0 0.0 5.2 5 0 0 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 KFQ91060.1 - 1.3e-05 25.5 1.8 0.8 10.0 0.0 4.8 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 KFQ91060.1 - 1.4e-05 24.9 1.6 0.087 12.5 0.0 4.1 4 0 0 4 4 4 1 AAA domain Sigma54_activat PF00158.26 KFQ91060.1 - 0.0011 18.7 0.0 0.7 9.6 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA PF00004.29 KFQ91060.1 - 0.0014 19.0 0.7 1.1 9.7 0.0 4.6 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) Ploopntkinase3 PF18751.1 KFQ91060.1 - 0.0057 16.6 0.0 0.26 11.2 0.0 2.5 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_18 PF13238.6 KFQ91060.1 - 0.01 16.4 4.0 3.2 8.3 0.0 4.6 5 0 0 5 5 3 0 AAA domain RNA_helicase PF00910.22 KFQ91060.1 - 0.011 16.1 0.2 16 6.0 0.0 4.0 3 0 0 3 3 3 0 RNA helicase DUF815 PF05673.13 KFQ91060.1 - 0.016 14.4 0.0 20 4.2 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF815) PhoH PF02562.16 KFQ91060.1 - 0.029 13.8 0.3 35 3.8 0.0 4.2 4 0 0 4 4 4 0 PhoH-like protein AAA_29 PF13555.6 KFQ91060.1 - 0.04 13.7 0.1 34 4.3 0.0 3.6 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KFQ91060.1 - 0.094 12.9 0.4 39 4.4 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 KFQ91060.1 - 0.13 12.6 3.2 22 5.4 0.0 4.3 4 0 0 4 4 4 0 AAA domain NACHT PF05729.12 KFQ91060.1 - 0.14 12.1 0.1 18 5.2 0.0 3.3 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 KFQ91060.1 - 0.33 11.4 4.6 55 4.3 0.0 5.1 5 0 0 5 5 3 0 ABC transporter HrpB7 PF09486.10 KFQ91060.1 - 1.5 9.2 20.1 1 9.7 2.3 3.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) PMSI1 PF15322.6 KFQ91060.1 - 1.7 8.0 3.5 41 3.5 0.0 2.3 2 0 0 2 2 2 0 Protein missing in infertile sperm 1, putative Lactamase_B_4 PF13691.6 KFQ91061.1 - 5.2e-15 54.9 0.0 6.2e-14 51.4 0.0 2.7 3 0 0 3 3 3 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 KFQ91061.1 - 7.5e-12 45.2 0.3 3.7e-10 39.7 0.5 2.9 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KFQ91061.1 - 0.00017 21.7 0.0 0.00041 20.4 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DASH_Ask1 PF08655.10 KFQ91061.1 - 0.062 13.2 0.1 0.73 9.8 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Ask1 Lactamase_B_6 PF16661.5 KFQ91061.1 - 0.086 12.3 0.0 8.7 5.7 0.0 2.3 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily domain Sacchrp_dh_NADP PF03435.18 KFQ91062.1 - 9.4e-07 29.2 0.0 1.7e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Consortin_C PF15281.6 KFQ91063.1 - 1.4e-54 182.9 0.1 4.4e-54 181.3 0.1 1.9 1 0 0 1 1 1 1 Consortin C-terminus TPR_7 PF13176.6 KFQ91063.1 - 0.038 14.0 0.3 0.54 10.4 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Clathrin PF00637.20 KFQ91063.1 - 0.43 10.4 4.2 2.1 8.2 2.9 2.4 2 0 0 2 2 2 0 Region in Clathrin and VPS RrnaAD PF00398.20 KFQ91064.1 - 2.8e-12 46.3 0.0 3.8e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase SET PF00856.28 KFQ91065.1 - 8.4e-13 49.1 0.1 9.6e-12 45.6 0.0 2.0 2 0 0 2 2 2 1 SET domain TPR_12 PF13424.6 KFQ91065.1 - 0.006 16.8 0.0 0.068 13.5 0.0 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat Kinesin PF00225.23 KFQ91066.1 - 6.4e-62 209.4 0.0 1e-61 208.8 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFQ91066.1 - 9.5e-16 58.1 0.0 1.9e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding AAA_33 PF13671.6 KFQ91068.1 - 7.6e-28 97.5 0.3 1.5e-27 96.5 0.1 1.5 2 0 0 2 2 2 1 AAA domain SPRY PF00622.28 KFQ91068.1 - 2.1e-14 53.7 0.2 2.1e-14 53.7 0.2 2.0 2 0 0 2 2 2 1 SPRY domain SRP54 PF00448.22 KFQ91068.1 - 0.022 14.4 0.2 0.038 13.6 0.2 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 KFQ91068.1 - 0.11 11.7 0.2 0.28 10.4 0.2 1.6 1 1 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 KFQ91068.1 - 0.12 12.9 0.0 0.35 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF3767 PF12597.8 KFQ91069.1 - 8.7e-14 51.2 0.1 1.1e-13 50.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Peptidase_C97 PF05903.14 KFQ91070.1 - 5.3e-39 133.5 0.0 6.9e-39 133.1 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KFQ91070.1 - 0.098 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Adenylsucc_synt PF00709.21 KFQ91071.1 - 2.1e-159 531.0 0.0 2.4e-159 530.8 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Spore_YpjB PF09577.10 KFQ91071.1 - 0.036 13.9 0.0 0.059 13.2 0.0 1.2 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) DUF5530 PF17670.1 KFQ91072.1 - 3.9e-21 75.3 0.1 4.6e-21 75.1 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5530) BTB PF00651.31 KFQ91073.1 - 2.2e-27 95.5 1.3 3.8e-27 94.7 1.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.6 KFQ91073.1 - 1.8e-15 56.3 29.8 0.00031 21.3 3.1 5.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFQ91073.1 - 7.7e-15 54.6 26.8 1.1e-07 31.9 1.9 5.7 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ91073.1 - 1.3e-13 50.6 34.7 0.00079 19.8 2.4 5.0 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFQ91073.1 - 3.6e-05 23.9 15.6 0.0037 17.5 0.0 4.7 4 1 1 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFQ91073.1 - 0.0011 18.9 22.3 0.35 10.9 2.0 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 KFQ91073.1 - 0.0027 18.0 0.1 0.0027 18.0 0.1 5.3 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFQ91073.1 - 0.012 15.3 19.9 0.28 11.0 0.4 4.6 5 0 0 5 5 5 0 zinc-finger C2H2-type Zn-C2H2_12 PF18112.1 KFQ91073.1 - 0.018 15.5 2.0 0.018 15.5 2.0 3.2 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain GAGA PF09237.11 KFQ91073.1 - 0.022 14.5 6.3 0.54 10.1 0.2 3.5 2 1 1 3 3 3 0 GAGA factor CpXC PF14353.6 KFQ91073.1 - 0.027 14.5 6.2 0.37 10.9 0.5 2.7 2 0 0 2 2 2 0 CpXC protein zf_C2H2_10 PF18414.1 KFQ91073.1 - 0.1 12.2 1.4 0.34 10.5 1.4 1.9 1 0 0 1 1 1 0 C2H2 type zinc-finger zf_UBZ PF18439.1 KFQ91073.1 - 0.16 11.6 7.0 3.6 7.2 0.2 3.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFQ91073.1 - 0.31 11.2 7.3 0.36 11.0 0.9 3.3 2 1 1 3 3 3 0 Zinc ribbon domain zf-LYAR PF08790.11 KFQ91073.1 - 0.32 10.9 9.6 0.63 10.0 0.4 4.2 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger PknG_rubred PF16919.5 KFQ91073.1 - 2.8 8.1 6.1 0.46 10.7 0.6 2.5 2 1 2 4 4 4 0 Protein kinase G rubredoxin domain zinc_ribbon_15 PF17032.5 KFQ91073.1 - 3 8.7 9.8 1.4e+02 3.3 6.4 3.5 2 1 1 3 3 3 0 zinc-ribbon family FYVE PF01363.21 KFQ91073.1 - 5.5 7.2 20.0 12 6.1 5.1 4.5 3 1 2 5 5 5 0 FYVE zinc finger XPA_N PF01286.18 KFQ91073.1 - 8.1 6.6 9.4 26 4.9 0.1 4.1 4 0 0 4 4 4 0 XPA protein N-terminal Pkinase PF00069.25 KFQ91074.1 - 2.9e-77 259.6 0.1 6.4e-77 258.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ91074.1 - 2.3e-36 125.4 0.0 3.2e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KFQ91074.1 - 1.1e-10 42.0 0.3 3.1e-10 40.5 0.1 1.9 2 0 0 2 2 2 1 PH domain Pkinase_C PF00433.24 KFQ91074.1 - 1.3e-09 38.6 2.7 2.7e-09 37.6 2.7 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFQ91074.1 - 1.3e-08 34.5 0.0 3.5e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KFQ91074.1 - 0.0091 15.6 0.4 0.97 9.0 0.1 2.3 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFQ91074.1 - 0.19 11.6 0.4 0.37 10.7 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family CCCAP PF15964.5 KFQ91075.1 - 0 1037.4 81.3 0 1037.2 81.3 1.0 1 0 0 1 1 1 1 Centrosomal colon cancer autoantigen protein family CENP-F_leu_zip PF10473.9 KFQ91075.1 - 0.009 16.0 12.5 0.009 16.0 12.5 7.8 4 1 3 8 8 8 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.12 KFQ91075.1 - 0.025 15.2 0.8 0.025 15.2 0.8 9.6 4 1 3 9 9 9 0 SlyX CEP170_C PF15308.6 KFQ91076.1 - 7.8e-262 870.8 61.3 7.8e-262 870.8 61.3 4.0 4 0 0 4 4 4 1 CEP170 C-terminus FHA PF00498.26 KFQ91076.1 - 3.8e-15 56.0 0.0 1.4e-14 54.2 0.0 2.1 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFQ91076.1 - 9.2e-09 35.5 0.0 9.2e-09 35.5 0.0 2.7 3 0 0 3 3 3 1 Inner membrane component of T3SS, cytoplasmic domain DUF4254 PF14063.6 KFQ91076.1 - 0.019 14.8 0.5 0.019 14.8 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4254) Trns_repr_metal PF02583.17 KFQ91076.1 - 0.21 12.0 1.5 1.4 9.3 0.0 2.6 2 0 0 2 2 2 0 Metal-sensitive transcriptional repressor PLDc_3 PF13918.6 KFQ91077.1 - 1.3e-82 275.7 1.1 2.7e-82 274.7 1.1 1.5 1 0 0 1 1 1 1 PLD-like domain PLDc_2 PF13091.6 KFQ91077.1 - 1.4e-12 47.6 0.1 6.9e-07 29.2 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KFQ91077.1 - 1.5e-08 34.5 1.2 0.00014 21.9 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif FAM83 PF07894.12 KFQ91077.1 - 0.078 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 FAM83 A-H Atg8 PF02991.16 KFQ91079.1 - 2.5e-39 133.6 0.3 2.9e-39 133.4 0.3 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KFQ91079.1 - 5.4e-06 26.7 0.1 6.6e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 WD40 PF00400.32 KFQ91080.1 - 4.6e-06 27.3 0.0 0.062 14.2 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KFQ91080.1 - 0.069 11.9 0.1 5 5.8 0.0 2.5 2 1 1 3 3 3 0 Nup133 N terminal like 7tm_1 PF00001.21 KFQ91081.1 - 2.5e-21 76.2 14.1 2.9e-21 76.0 14.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) O-ag_pol_Wzy PF14296.6 KFQ91081.1 - 0.00038 19.3 4.7 0.00053 18.8 4.7 1.2 1 0 0 1 1 1 1 O-antigen polysaccharide polymerase Wzy Herpes_UL49_5 PF05702.11 KFQ91081.1 - 0.025 14.6 1.8 1.2 9.3 0.3 2.6 2 0 0 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein Pex24p PF06398.11 KFQ91081.1 - 0.27 10.2 6.8 3.8 6.4 0.2 2.3 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin DHHC PF01529.20 KFQ91081.1 - 3.8 7.6 9.0 0.54 10.4 5.0 1.6 2 0 0 2 2 2 0 DHHC palmitoyltransferase Mannosyl_trans PF05007.13 KFQ91082.1 - 2.1e-90 303.1 30.1 4.1e-88 295.6 30.1 2.0 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KFQ91082.1 - 0.0024 17.0 31.1 0.0059 15.7 25.1 2.8 1 1 1 2 2 2 1 GPI transamidase subunit PIG-U RGS_DHEX PF18148.1 KFQ91083.1 - 2.9e-50 168.5 1.6 2.9e-50 168.5 1.6 2.2 2 0 0 2 2 2 1 Regulator of G-protein signalling DHEX domain RGS PF00615.19 KFQ91083.1 - 1.5e-35 122.0 0.3 5.4e-35 120.2 0.0 2.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 KFQ91083.1 - 1e-18 67.1 0.0 6.8e-18 64.5 0.0 2.3 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.22 KFQ91083.1 - 3.5e-15 55.8 0.1 1.4e-14 53.8 0.1 2.1 1 0 0 1 1 1 1 GGL domain RGS-like PF09128.11 KFQ91083.1 - 0.081 12.6 0.0 0.081 12.6 0.0 2.1 3 0 0 3 3 3 0 Regulator of G protein signalling-like domain DAN PF03045.15 KFQ91084.1 - 5.2e-41 139.2 10.8 7.1e-41 138.8 10.8 1.1 1 0 0 1 1 1 1 DAN domain Sfi1_C PF10638.9 KFQ91084.1 - 0.091 13.5 0.9 0.15 12.9 0.2 1.7 2 0 0 2 2 2 0 Spindle body associated protein C-terminus NTP_transf_9 PF04248.12 KFQ91084.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF427) FH2 PF02181.23 KFQ91085.1 - 0.0069 15.5 0.9 0.0091 15.2 0.2 1.5 2 0 0 2 2 2 1 Formin Homology 2 Domain FH2 PF02181.23 KFQ91086.1 - 1.2e-81 274.8 5.8 1.4e-81 274.6 5.8 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain IFN-gamma PF00714.17 KFQ91086.1 - 0.079 12.8 3.6 0.082 12.8 0.2 2.5 2 1 0 2 2 2 0 Interferon gamma 7tm_1 PF00001.21 KFQ91087.1 - 1e-78 264.3 1.5 1.4e-78 263.8 1.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ91087.1 - 8.3e-09 35.2 6.0 8.3e-09 35.2 6.0 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFQ91087.1 - 8.7e-08 32.1 8.4 8.7e-08 32.1 8.4 2.4 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFQ91087.1 - 5.5e-06 26.3 11.8 3.5e-05 23.7 3.9 2.4 2 1 0 2 2 2 2 Olfactory receptor CitMHS PF03600.16 KFQ91087.1 - 0.83 8.8 6.2 0.96 8.6 6.2 1.3 1 1 0 1 1 1 0 Citrate transporter RYDR_ITPR PF01365.21 KFQ91088.1 - 3.7e-139 460.8 5.1 1.4e-73 246.7 0.0 4.2 4 0 0 4 4 4 2 RIH domain RyR PF02026.16 KFQ91088.1 - 2.5e-124 405.8 15.5 4.5e-33 113.3 0.0 5.6 5 0 0 5 5 5 4 RyR domain RR_TM4-6 PF06459.12 KFQ91088.1 - 4.6e-95 318.7 0.5 4.6e-95 318.7 0.5 2.3 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 SPRY PF00622.28 KFQ91088.1 - 1.5e-65 218.7 1.2 2.4e-20 72.8 0.1 3.6 3 0 0 3 3 3 3 SPRY domain MIR PF02815.19 KFQ91088.1 - 4.2e-57 193.0 0.1 8.8e-55 185.4 0.0 2.9 2 0 0 2 2 2 1 MIR domain Ins145_P3_rec PF08709.11 KFQ91088.1 - 4.9e-46 156.6 0.0 2.5e-44 151.1 0.0 2.7 2 0 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RIH_assoc PF08454.11 KFQ91088.1 - 2.2e-33 114.1 3.0 9.7e-33 112.0 0.3 3.6 4 0 0 4 4 4 1 RyR and IP3R Homology associated Ion_trans PF00520.31 KFQ91088.1 - 2e-14 53.4 9.2 3.8e-13 49.2 5.7 3.5 3 0 0 3 3 3 1 Ion transport protein EF-hand_8 PF13833.6 KFQ91088.1 - 4.9e-07 29.5 0.6 5.4e-06 26.2 0.2 3.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 KFQ91088.1 - 4.8e-06 26.9 3.1 6.4e-06 26.5 1.0 2.5 2 0 0 2 2 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFQ91088.1 - 0.00011 21.4 0.4 0.0023 17.4 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KFQ91088.1 - 0.0038 17.0 0.0 0.022 14.6 0.0 2.3 1 0 0 1 1 1 1 EF-hand domain GWT1 PF06423.12 KFQ91088.1 - 0.64 10.1 3.1 3.6 7.7 0.0 3.3 3 0 0 3 3 3 0 GWT1 YjfB_motility PF14070.6 KFQ91088.1 - 0.81 9.9 7.6 2.9 8.1 7.6 2.0 1 0 0 1 1 1 0 Putative motility protein Met_synt_B12 PF02965.17 KFQ91089.1 - 5.7e-113 376.9 0.0 8.5e-113 376.4 0.0 1.3 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 KFQ91089.1 - 4.6e-78 262.7 0.0 1e-77 261.6 0.0 1.6 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 KFQ91089.1 - 4.7e-58 196.7 0.1 2.7e-57 194.3 0.0 2.3 3 0 0 3 3 3 1 Pterin binding enzyme B12-binding_2 PF02607.17 KFQ91089.1 - 1.9e-23 82.6 0.0 4.6e-23 81.4 0.0 1.7 1 0 0 1 1 1 1 B12 binding domain B12-binding PF02310.19 KFQ91089.1 - 1.7e-17 63.6 0.1 5.8e-17 61.9 0.1 1.9 1 0 0 1 1 1 1 B12 binding domain CdhD PF03599.16 KFQ91089.1 - 0.0042 15.9 0.1 0.0078 15.0 0.1 1.4 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit IPT PF01745.16 KFQ91089.1 - 0.072 12.5 0.1 0.19 11.1 0.1 1.7 1 0 0 1 1 1 0 Isopentenyl transferase Spectrin PF00435.21 KFQ91090.1 - 1.1e-71 237.9 33.6 4.6e-23 81.7 8.4 4.4 4 0 0 4 4 4 4 Spectrin repeat CH PF00307.31 KFQ91090.1 - 1.2e-53 179.9 0.4 7e-27 93.8 0.0 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KFQ91090.1 - 7.2e-28 96.5 0.0 3.9e-27 94.2 0.0 2.4 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_1 PF00036.32 KFQ91090.1 - 7.7e-09 34.5 1.0 0.004 16.6 0.0 2.9 2 0 0 2 2 2 2 EF hand CAMSAP_CH PF11971.8 KFQ91090.1 - 1.5e-08 34.4 0.0 3.2e-07 30.1 0.0 2.5 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_7 PF13499.6 KFQ91090.1 - 1.3e-06 28.8 1.7 3.9e-06 27.2 0.4 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KFQ91090.1 - 2.4e-06 27.3 3.7 4.8e-06 26.3 0.3 3.2 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 KFQ91090.1 - 8.9e-05 22.1 3.3 0.024 14.5 0.5 3.3 3 0 0 3 3 3 2 EF-hand domain IATP PF04568.12 KFQ91090.1 - 0.03 14.8 5.1 0.28 11.7 0.5 3.3 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP EF-hand_11 PF08976.11 KFQ91090.1 - 0.043 14.7 0.2 0.21 12.5 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain XisI PF08869.11 KFQ91090.1 - 0.25 11.7 6.6 0.075 13.4 1.2 2.7 2 0 0 2 2 2 0 XisI protein Gal-bind_lectin PF00337.22 KFQ91091.1 - 3.1e-77 256.6 0.1 3.4e-39 133.5 0.0 2.0 2 0 0 2 2 2 2 Galactoside-binding lectin WIF PF02019.18 KFQ91091.1 - 0.0012 18.5 0.0 0.11 12.2 0.0 2.4 2 0 0 2 2 2 2 WIF domain DUF1080 PF06439.11 KFQ91091.1 - 0.048 13.8 0.0 0.34 11.0 0.0 2.1 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1080) Death PF00531.22 KFQ91092.1 - 7.7e-10 38.8 0.0 1.4e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Death domain ERO1 PF04137.15 KFQ91093.1 - 1.9e-127 425.3 0.0 2.2e-127 425.1 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) PspB PF06667.12 KFQ91094.1 - 0.72 9.9 6.7 0.21 11.6 2.8 2.2 2 0 0 2 2 2 0 Phage shock protein B Tmemb_161AB PF10268.9 KFQ91095.1 - 5.7e-180 599.0 15.4 6.5e-180 598.8 15.4 1.0 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB Peptidase_A17 PF05380.13 KFQ91096.1 - 0.26 11.3 1.9 0.32 11.0 0.1 1.9 2 0 0 2 2 2 0 Pao retrotransposon peptidase SH2 PF00017.24 KFQ91097.1 - 1.9e-18 66.3 0.1 3e-18 65.7 0.1 1.3 1 0 0 1 1 1 1 SH2 domain Nucleos_tra2_C PF07662.13 KFQ91098.1 - 3.2e-76 255.8 6.9 3.2e-76 255.8 6.9 2.0 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KFQ91098.1 - 1.3e-21 77.0 7.1 1.3e-21 77.0 7.1 3.4 4 1 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 KFQ91098.1 - 3.8e-10 40.0 6.0 3.8e-10 40.0 6.0 3.8 4 2 0 4 4 4 1 Nucleoside recognition Alpha_kinase PF02816.18 KFQ91099.1 - 3.2e-25 89.3 0.0 3.7e-25 89.1 0.0 1.0 1 0 0 1 1 1 1 Alpha-kinase family Peptidase_C14 PF00656.22 KFQ91100.1 - 4.4e-20 72.7 0.0 2e-19 70.5 0.0 1.8 1 1 0 1 1 1 1 Caspase domain Peptidase_S24 PF00717.23 KFQ91101.1 - 1.4e-09 37.8 0.1 2.3e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like Bombesin PF02044.17 KFQ91102.1 - 4.9e-09 35.6 3.1 8.4e-09 34.9 3.1 1.4 1 0 0 1 1 1 1 Bombesin-like peptide SAM_2 PF07647.17 KFQ91103.1 - 1.3e-08 34.9 0.0 1.9e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFQ91103.1 - 5.8e-07 29.8 0.1 9.4e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 KFQ91103.1 - 0.0057 16.9 0.1 0.0099 16.1 0.1 1.6 1 1 0 1 1 1 1 Ste50p, sterile alpha motif Ras PF00071.22 KFQ91104.1 - 5.6e-57 191.9 0.0 6.3e-57 191.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ91104.1 - 4.7e-23 81.7 0.0 7.1e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ91104.1 - 3.5e-10 39.6 0.0 4.9e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFQ91104.1 - 0.028 13.8 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Frag1 PF10277.9 KFQ91105.1 - 3.2e-14 53.0 6.8 3.5e-14 52.9 6.8 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Nup96 PF12110.8 KFQ91106.1 - 7.7e-90 300.9 1.7 1.2e-89 300.3 1.7 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 KFQ91106.1 - 1e-47 162.0 0.0 1.7e-47 161.3 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KFQ91106.1 - 5e-06 27.3 199.6 0.002 19.0 35.0 6.5 2 2 5 7 7 7 4 Nucleoporin FG repeat region Neur_chan_LBD PF02931.23 KFQ91107.1 - 5.8e-69 231.8 0.1 7.1e-69 231.5 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFQ91107.1 - 4.9e-44 151.2 2.8 1.9e-41 142.7 2.8 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region zf-AN1 PF01428.16 KFQ91108.1 - 7.6e-10 38.8 8.2 1.2e-09 38.1 8.2 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger FAM53 PF15242.6 KFQ91108.1 - 0.029 14.2 10.8 0.041 13.7 10.8 1.1 1 0 0 1 1 1 0 Family of FAM53 Rad9 PF04139.13 KFQ91109.1 - 9.7e-09 35.0 0.0 1.3e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Rad9 MAGE_N PF12440.8 KFQ91109.1 - 0.2 12.4 4.5 0.7 10.6 4.3 1.8 1 1 1 2 2 2 0 Melanoma associated antigen family N terminal Metallophos PF00149.28 KFQ91110.1 - 1e-40 140.4 0.1 1.3e-40 140.1 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFQ91110.1 - 3.5e-17 62.6 0.6 8.8e-17 61.3 0.4 1.8 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Pkinase_Tyr PF07714.17 KFQ91111.1 - 1.1e-93 313.3 0.0 1.5e-93 312.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.24 KFQ91111.1 - 1.8e-54 182.6 0.1 2.1e-29 101.9 0.1 2.7 2 0 0 2 2 2 2 Receptor L domain Pkinase PF00069.25 KFQ91111.1 - 1.2e-40 139.6 0.0 1.9e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.20 KFQ91111.1 - 2.2e-19 69.8 27.7 2.2e-19 69.8 27.7 2.2 2 1 0 2 2 2 1 Furin-like cysteine rich region fn3 PF00041.21 KFQ91111.1 - 4.9e-18 65.3 3.8 4.7e-05 23.6 0.2 4.5 4 0 0 4 4 4 4 Fibronectin type III domain Kinase-like PF14531.6 KFQ91111.1 - 0.00093 18.6 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like B2 PF11473.8 KFQ91111.1 - 0.055 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA binding protein B2 Insulin_TMD PF17870.1 KFQ91111.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Pkinase PF00069.25 KFQ91112.1 - 1.2e-67 228.1 0.0 1.3e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ91112.1 - 1.9e-36 125.7 0.0 2.3e-36 125.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFQ91112.1 - 3.4e-05 23.3 0.2 7.3e-05 22.2 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFQ91112.1 - 6.9e-05 22.5 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KFQ91112.1 - 0.00014 20.7 0.0 0.00016 20.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFQ91112.1 - 0.0024 17.8 0.1 0.0097 15.9 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFQ91112.1 - 0.008 15.5 0.1 0.018 14.4 0.1 1.6 1 1 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 KFQ91112.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Toxin_30 PF08117.11 KFQ91112.1 - 0.17 12.1 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 Ptu family SH2 PF00017.24 KFQ91113.1 - 1.8e-17 63.2 0.0 2.6e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 SH2 domain VIR_N PF15912.5 KFQ91113.1 - 4.4 6.8 7.6 1.3 8.6 4.0 1.7 2 0 0 2 2 2 0 Virilizer, N-terminal PRCC PF10253.9 KFQ91114.1 - 4.5e-54 184.5 9.4 4.5e-54 184.5 9.4 2.8 2 1 1 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting TEBP_beta PF07404.11 KFQ91114.1 - 0.054 12.9 3.8 0.095 12.0 3.8 1.3 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) DnaJ_C PF01556.18 KFQ91118.1 - 1.1e-44 152.1 0.0 1.4e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KFQ91118.1 - 5.2e-13 49.1 20.1 8.6e-13 48.5 20.1 1.4 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.31 KFQ91118.1 - 2.1e-05 24.5 0.2 3.6e-05 23.8 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain HypA PF01155.19 KFQ91118.1 - 0.021 14.9 9.2 0.069 13.2 0.6 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 KFQ91118.1 - 0.034 14.1 13.6 0.28 11.2 4.1 3.2 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Filament PF00038.21 KFQ91119.1 - 7.3e-40 137.5 39.4 8.7e-40 137.2 39.4 1.1 1 0 0 1 1 1 1 Intermediate filament protein BRE1 PF08647.11 KFQ91119.1 - 0.016 15.2 5.9 0.016 15.2 5.9 4.1 3 2 2 5 5 5 0 BRE1 E3 ubiquitin ligase Peptidase_C58 PF03543.14 KFQ91119.1 - 0.28 10.9 13.1 0.14 11.8 1.9 2.3 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen YlqD PF11068.8 KFQ91119.1 - 0.3 11.5 37.2 1 9.7 0.0 4.4 2 2 1 3 3 3 0 YlqD protein DUF3037 PF11236.8 KFQ91119.1 - 0.94 9.9 12.9 0.68 10.4 4.4 3.5 2 2 0 2 2 2 0 Protein of unknown function (DUF3037) DUF1664 PF07889.12 KFQ91119.1 - 2.5 8.1 15.6 2.4 8.2 0.1 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) DUF4472 PF14739.6 KFQ91119.1 - 3.5 8.4 37.8 5.1 7.9 6.7 4.2 2 2 2 4 4 4 0 Domain of unknown function (DUF4472) DUF3708 PF12501.8 KFQ91119.1 - 4.1 7.2 6.0 1.1 9.0 1.1 2.0 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter DUF4407 PF14362.6 KFQ91119.1 - 9.2 5.5 23.5 5.2 6.3 10.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Xlink PF00193.17 KFQ91120.1 - 6.3e-63 209.2 0.1 2.2e-34 117.7 0.1 2.2 2 0 0 2 2 2 2 Extracellular link domain V-set PF07686.17 KFQ91120.1 - 3.4e-15 56.2 0.0 6.4e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFQ91120.1 - 1.5e-08 35.1 0.0 3.4e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ91120.1 - 3.5e-08 33.4 0.0 6.6e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFQ91120.1 - 1.5e-05 25.1 0.0 9.8e-05 22.5 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFQ91120.1 - 0.00035 20.6 0.0 0.00069 19.6 0.0 1.5 1 0 0 1 1 1 1 Izumo-like Immunoglobulin domain Ig_2 PF13895.6 KFQ91120.1 - 0.0043 17.4 0.1 0.032 14.5 0.1 2.2 1 1 0 1 1 1 1 Immunoglobulin domain Lectin_C PF00059.21 KFQ91120.1 - 0.021 15.6 0.7 4.7 8.0 0.1 2.4 2 0 0 2 2 2 0 Lectin C-type domain SRF-TF PF00319.18 KFQ91121.1 - 1.1e-19 69.6 0.4 1.9e-19 68.9 0.4 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C PF12347.8 KFQ91121.1 - 1.5e-12 47.3 4.7 1.7e-12 47.2 0.0 3.0 2 0 0 2 2 2 1 Holliday junction regulator protein family C-terminal repeat ANAPC_CDC26 PF10471.9 KFQ91121.1 - 0.0016 19.3 4.8 0.0036 18.1 4.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 SUIM_assoc PF16619.5 KFQ91121.1 - 0.0081 16.2 8.1 0.027 14.5 8.1 1.9 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 KFQ91121.1 - 0.54 10.2 11.1 0.74 9.7 11.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RasGAP PF00616.19 KFQ91122.1 - 1.8e-54 184.6 0.0 5.3e-54 183.1 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KFQ91122.1 - 1.6e-34 119.0 10.1 1.6e-34 119.0 10.1 2.8 3 0 0 3 3 3 1 RasGAP C-terminus CH PF00307.31 KFQ91122.1 - 8.6e-18 64.5 0.0 2.5e-17 63.0 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.27 KFQ91122.1 - 6.2e-17 59.7 25.8 4.1e-05 23.0 3.9 5.2 4 0 0 4 4 4 4 IQ calmodulin-binding motif CAMSAP_CH PF11971.8 KFQ91122.1 - 0.014 15.2 0.0 0.049 13.5 0.0 1.9 1 0 0 1 1 1 0 CAMSAP CH domain AKAP7_RIRII_bdg PF10470.9 KFQ91122.1 - 0.02 14.9 0.0 0.068 13.2 0.0 1.9 1 0 0 1 1 1 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein M-inducer_phosp PF06617.13 KFQ91122.1 - 0.038 13.3 0.2 0.083 12.2 0.2 1.5 1 0 0 1 1 1 0 M-phase inducer phosphatase DUF1198 PF06711.11 KFQ91122.1 - 0.083 12.9 0.1 0.65 10.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1198) SHD1 PF03983.12 KFQ91122.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 SLA1 homology domain 1, SHD1 Syntaxin_2 PF14523.6 KFQ91122.1 - 6.6 7.2 10.3 1.7 9.1 3.6 3.0 2 0 0 2 2 2 0 Syntaxin-like protein YjeF_N PF03853.15 KFQ91123.1 - 6e-36 123.9 0.0 7.3e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus ubiquitin PF00240.23 KFQ91124.1 - 1.3e-12 47.3 0.1 2.2e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family STI1 PF17830.1 KFQ91124.1 - 2.5e-08 33.7 60.1 0.00025 20.9 11.7 7.1 5 2 2 7 7 7 5 STI1 domain UBA PF00627.31 KFQ91124.1 - 1.1e-06 28.4 0.9 1.1e-06 28.4 0.9 2.5 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.8 KFQ91124.1 - 0.0017 18.1 0.1 0.0032 17.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Arm_2 PF04826.13 KFQ91124.1 - 0.0068 15.9 0.3 0.0068 15.9 0.3 2.9 3 0 0 3 3 3 1 Armadillo-like Rad60-SLD_2 PF13881.6 KFQ91124.1 - 0.014 15.4 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KFQ91124.1 - 0.017 15.5 0.2 0.045 14.1 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain HOIP-UBA PF16678.5 KFQ91124.1 - 0.049 13.6 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 HOIP UBA domain pair CUE PF02845.16 KFQ91124.1 - 0.053 13.2 0.0 0.25 11.1 0.0 2.3 1 0 0 1 1 1 0 CUE domain ComX PF05952.12 KFQ91124.1 - 1 9.4 9.1 35 4.4 0.2 5.1 4 1 1 5 5 5 0 Bacillus competence pheromone ComX Robl_LC7 PF03259.17 KFQ91125.1 - 1.4e-13 50.4 0.1 1.6e-13 50.3 0.1 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain Ras PF00071.22 KFQ91126.1 - 2e-57 193.3 0.3 2.2e-57 193.2 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ91126.1 - 6.9e-32 110.2 0.1 9.4e-32 109.8 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ91126.1 - 1.2e-12 47.7 0.1 1.3e-12 47.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFQ91126.1 - 7e-08 32.5 0.1 8.5e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFQ91126.1 - 2.9e-06 27.3 0.9 0.041 13.8 0.1 2.1 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KFQ91126.1 - 8.2e-05 22.1 0.0 9.5e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFQ91126.1 - 0.00087 18.8 0.0 0.0059 16.1 0.0 1.9 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KFQ91126.1 - 0.001 19.3 0.0 0.0051 17.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.18 KFQ91126.1 - 0.0018 17.8 0.7 0.011 15.3 0.7 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_7 PF12775.7 KFQ91126.1 - 0.0025 17.3 0.1 0.0045 16.5 0.1 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 KFQ91126.1 - 0.006 16.6 0.0 0.0091 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KFQ91126.1 - 0.0089 16.3 0.2 0.46 10.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 KFQ91126.1 - 0.0093 15.7 0.1 0.035 13.9 0.0 1.9 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 KFQ91126.1 - 0.011 15.5 0.1 0.022 14.5 0.0 1.6 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.6 KFQ91126.1 - 0.015 15.3 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFQ91126.1 - 0.017 15.5 0.1 0.022 15.2 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 KFQ91126.1 - 0.031 13.7 0.0 0.065 12.6 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein cobW PF02492.19 KFQ91126.1 - 0.042 13.4 0.2 2.2 7.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.14 KFQ91126.1 - 0.054 12.7 0.0 0.068 12.4 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain MobB PF03205.14 KFQ91126.1 - 0.054 13.4 0.1 2.3 8.1 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.27 KFQ91126.1 - 0.059 13.9 0.1 0.13 12.8 0.0 1.4 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 KFQ91126.1 - 0.09 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Ras PF00071.22 KFQ91127.1 - 6.9e-62 207.8 0.1 8.1e-62 207.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ91127.1 - 6.3e-35 120.0 0.1 9e-35 119.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ91127.1 - 1.3e-12 47.5 0.0 1.7e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFQ91127.1 - 1.9e-07 31.2 0.0 2.9e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFQ91127.1 - 7.1e-05 22.8 0.1 0.013 15.4 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KFQ91127.1 - 9.4e-05 22.7 0.1 0.00079 19.7 0.0 2.2 2 1 0 2 2 1 1 AAA domain GTP_EFTU PF00009.27 KFQ91127.1 - 0.00077 19.0 0.1 0.0025 17.4 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFQ91127.1 - 0.0052 16.2 0.0 0.0081 15.5 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KFQ91127.1 - 0.0059 17.0 0.0 0.0096 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain FAD-SLDH PF12318.8 KFQ91127.1 - 0.0075 16.4 0.1 0.013 15.6 0.1 1.4 1 0 0 1 1 1 1 Membrane bound FAD containing D-sorbitol dehydrogenase SRPRB PF09439.10 KFQ91127.1 - 0.011 15.1 0.0 0.022 14.2 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KFQ91127.1 - 0.019 15.5 0.1 0.027 15.0 0.1 1.5 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 KFQ91127.1 - 0.028 14.0 0.1 0.061 12.9 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.6 KFQ91127.1 - 0.028 14.5 0.1 0.062 13.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFQ91127.1 - 0.033 13.9 0.1 0.066 12.9 0.0 1.5 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KFQ91127.1 - 0.037 13.4 0.0 0.18 11.2 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein MCM PF00493.23 KFQ91127.1 - 0.099 11.7 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_5 PF07728.14 KFQ91127.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KFQ91127.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Filament PF00038.21 KFQ91128.1 - 4.8e-102 341.7 43.1 6.6e-102 341.3 43.1 1.2 1 0 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 KFQ91128.1 - 7.1e-16 58.6 0.0 1.3e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Lamin Tail Domain CENP-F_leu_zip PF10473.9 KFQ91128.1 - 0.0014 18.7 57.0 0.021 14.9 22.6 3.7 2 1 0 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 KFQ91128.1 - 0.017 15.2 60.0 0.94 9.6 5.8 4.4 3 2 0 3 3 3 0 TPR/MLP1/MLP2-like protein LPP PF04728.13 KFQ91128.1 - 0.051 14.0 11.7 1.2 9.6 0.3 4.1 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DUF1664 PF07889.12 KFQ91128.1 - 0.12 12.4 26.9 1.6 8.8 3.8 4.8 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) AAA_11 PF13086.6 KFQ91128.1 - 0.14 11.9 0.0 0.14 11.9 0.0 3.0 1 1 1 2 2 1 0 AAA domain DUF5320 PF17253.2 KFQ91128.1 - 0.25 12.4 0.0 0.25 12.4 0.0 4.3 5 1 0 5 5 5 0 Family of unknown function (DUF5320) Rop-like PF05082.13 KFQ91128.1 - 0.31 10.9 10.7 1.4 8.7 1.1 3.3 3 0 0 3 3 3 0 Rop-like DUF4407 PF14362.6 KFQ91128.1 - 0.78 9.0 35.8 1.6 8.0 10.8 4.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 KFQ91128.1 - 0.98 8.2 54.3 1.1 8.1 5.9 3.5 2 1 1 3 3 3 0 Spc7 kinetochore protein NPV_P10 PF05531.12 KFQ91128.1 - 2.8 8.5 12.1 13 6.4 1.7 3.7 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Cnn_1N PF07989.11 KFQ91128.1 - 2.9 8.1 39.9 0.12 12.5 0.6 5.5 2 1 4 6 6 6 0 Centrosomin N-terminal motif 1 Sema PF01403.19 KFQ91129.1 - 2.4e-86 290.2 0.0 2.7e-86 290.1 0.0 1.0 1 0 0 1 1 1 1 Sema domain zf-U11-48K PF05253.12 KFQ91129.1 - 0.088 12.8 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 U11-48K-like CHHC zinc finger Mito_carr PF00153.27 KFQ91130.1 - 1.3e-50 169.3 6.3 2.9e-16 59.2 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Nnf1 PF03980.14 KFQ91131.1 - 1.5e-22 80.1 0.7 2.2e-22 79.5 0.7 1.3 1 0 0 1 1 1 1 Nnf1 HlyIII PF03006.20 KFQ91133.1 - 1.7e-25 90.1 14.5 9.8e-25 87.6 14.5 1.9 1 1 0 1 1 1 1 Haemolysin-III related Cpn60_TCP1 PF00118.24 KFQ91134.1 - 9e-73 245.6 1.7 1e-72 245.4 1.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TRAP_beta PF05753.14 KFQ91135.1 - 1.8e-50 170.8 0.0 2.1e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) Tropomyosin PF00261.20 KFQ91136.1 - 1.8e-103 345.1 88.5 3e-98 327.9 61.9 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 KFQ91136.1 - 5e-38 130.5 76.4 7.8e-34 116.9 44.4 3.1 1 1 1 2 2 2 2 Tropomyosin like Laminin_II PF06009.12 KFQ91136.1 - 1.4e-08 34.9 34.3 1e-05 25.6 7.2 3.8 1 1 3 4 4 4 3 Laminin Domain II CLZ PF16526.5 KFQ91136.1 - 2.4e-07 31.0 51.7 3.8e-06 27.2 12.4 5.0 2 2 2 5 5 5 3 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ERM PF00769.19 KFQ91136.1 - 0.00064 19.6 77.0 0.15 11.9 47.3 2.4 1 1 1 2 2 2 2 Ezrin/radixin/moesin family TMF_DNA_bd PF12329.8 KFQ91136.1 - 0.00087 19.2 9.3 0.00087 19.2 9.3 6.1 2 2 4 6 6 6 2 TATA element modulatory factor 1 DNA binding XhlA PF10779.9 KFQ91136.1 - 0.002 18.3 3.4 0.002 18.3 3.4 6.6 1 1 4 6 6 6 2 Haemolysin XhlA DUF745 PF05335.13 KFQ91136.1 - 0.0067 16.2 51.0 0.17 11.6 9.6 3.2 1 1 2 3 3 3 2 Protein of unknown function (DUF745) CENP-F_leu_zip PF10473.9 KFQ91136.1 - 0.0082 16.2 30.3 0.0082 16.2 30.3 2.2 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KFQ91136.1 - 0.012 15.9 64.1 0.012 15.8 23.7 3.3 1 1 2 3 3 2 0 Autophagy protein 16 (ATG16) HrpB7 PF09486.10 KFQ91136.1 - 0.014 15.8 55.9 0.016 15.6 17.9 4.6 1 1 4 5 5 5 0 Bacterial type III secretion protein (HrpB7) DHR10 PF18595.1 KFQ91136.1 - 0.016 15.3 16.4 0.016 15.3 16.4 4.3 1 1 3 4 4 4 0 Designed helical repeat protein 10 domain SlyX PF04102.12 KFQ91136.1 - 0.027 15.1 0.6 0.027 15.1 0.6 5.3 1 1 5 6 6 6 0 SlyX DUF1664 PF07889.12 KFQ91136.1 - 0.033 14.2 33.9 0.21 11.6 2.9 4.2 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 KFQ91136.1 - 0.05 13.1 57.0 1.2 8.5 21.5 2.6 1 1 2 3 3 3 0 Golgin subfamily A member 5 MscS_porin PF12795.7 KFQ91136.1 - 0.063 12.8 53.6 0.99 8.9 8.6 3.0 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF1794 PF08768.11 KFQ91136.1 - 0.22 11.4 5.2 4.2 7.3 0.1 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF1794) AAA_13 PF13166.6 KFQ91136.1 - 0.26 9.9 50.8 0.45 9.1 13.3 2.1 1 1 1 2 2 2 0 AAA domain Laminin_I PF06008.14 KFQ91136.1 - 0.29 10.8 58.1 0.58 9.8 20.5 3.3 1 1 2 3 3 3 0 Laminin Domain I Lebercilin PF15619.6 KFQ91136.1 - 0.33 10.6 65.5 1.2 8.8 29.2 3.4 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease ADIP PF11559.8 KFQ91136.1 - 0.43 10.7 52.3 1.6 8.8 14.2 4.0 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding MAD PF05557.13 KFQ91136.1 - 0.61 8.4 60.2 1.1 7.5 25.9 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF16 PF01519.16 KFQ91136.1 - 0.72 10.4 40.8 0.37 11.3 0.4 4.5 1 1 3 4 4 4 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 KFQ91136.1 - 0.94 10.0 16.0 2.7 8.5 0.7 4.4 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 KFQ91136.1 - 0.97 9.6 33.0 0.24 11.6 7.3 3.4 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 KFQ91136.1 - 1.3 8.5 38.0 7.7 6.0 13.4 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit EzrA PF06160.12 KFQ91136.1 - 1.4 7.0 58.3 0.28 9.3 7.6 3.1 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA Baculo_PEP_C PF04513.12 KFQ91136.1 - 2 8.4 16.7 9.4 6.3 3.7 3.8 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.12 KFQ91136.1 - 2.9 6.3 22.8 2.7 6.4 1.2 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family TTKRSYEDQ PF10212.9 KFQ91136.1 - 4.8 6.0 39.1 1.1 8.2 15.0 2.1 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF3450 PF11932.8 KFQ91136.1 - 5 6.4 52.6 0.013 14.8 10.2 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) GAS PF13851.6 KFQ91136.1 - 5.2 6.4 66.8 0.63 9.4 16.6 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding FPP PF05911.11 KFQ91136.1 - 6.6 4.8 62.7 0.89 7.7 20.5 2.9 1 1 2 3 3 3 0 Filament-like plant protein, long coiled-coil Fmp27_WPPW PF10359.9 KFQ91136.1 - 6.7 5.4 40.0 0.26 10.1 10.2 2.7 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain BST2 PF16716.5 KFQ91136.1 - 7 7.3 50.2 0.11 13.1 8.8 4.9 1 1 6 7 7 7 0 Bone marrow stromal antigen 2 HOOK PF05622.12 KFQ91136.1 - 7.2 4.6 60.5 0.013 13.7 16.1 2.2 1 1 1 2 2 2 0 HOOK protein SNARE PF05739.19 KFQ91136.1 - 7.7 6.6 15.8 2.3 8.3 0.1 5.1 5 0 0 5 5 5 0 SNARE domain T3SSipB PF16535.5 KFQ91136.1 - 9 6.8 49.9 6.5 7.2 7.4 4.6 1 1 3 4 4 4 0 Type III cell invasion protein SipB NICE-3 PF07406.11 KFQ91137.1 - 1.7e-39 135.7 0.2 2.7e-39 135.0 0.0 1.4 2 0 0 2 2 2 1 NICE-3 protein PhoLip_ATPase_C PF16212.5 KFQ91139.1 - 1.1e-86 290.7 21.9 1.1e-86 290.7 21.9 2.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFQ91139.1 - 1e-27 95.6 6.5 2.7e-27 94.3 6.5 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KFQ91139.1 - 1.4e-11 44.4 0.0 7.5e-11 42.0 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFQ91139.1 - 1.9e-10 41.4 0.3 0.00081 19.7 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFQ91139.1 - 6.5e-07 29.1 0.2 3.8e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFQ91139.1 - 0.00055 19.8 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Formyl_trans_C PF02911.18 KFQ91139.1 - 0.12 12.6 0.0 0.47 10.7 0.0 2.0 2 0 0 2 2 2 0 Formyl transferase, C-terminal domain DUF3899 PF13038.6 KFQ91139.1 - 6 7.4 9.1 0.31 11.6 2.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) UQ_con PF00179.26 KFQ91140.1 - 1.7e-10 40.7 0.0 5.9e-10 38.9 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFQ91140.1 - 0.0041 16.8 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic E2 family B IL13 PF03487.13 KFQ91140.1 - 0.03 14.1 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Interleukin-13 NA37 PF04245.13 KFQ91140.1 - 0.065 12.7 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein Josephin PF02099.17 KFQ91140.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.4 1 1 0 1 1 1 0 Josephin KIAA1430 PF13879.6 KFQ91140.1 - 0.41 11.4 2.9 0.83 10.5 0.2 2.5 2 1 1 3 3 3 0 KIAA1430 homologue PID PF00640.23 KFQ91141.1 - 2.9e-47 160.2 0.0 4.1e-47 159.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.24 KFQ91141.1 - 1.2e-13 51.0 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 SH2 domain Delta_lysin PF05372.11 KFQ91141.1 - 0.11 11.8 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 Delta lysin family PAPS_reduct PF01507.19 KFQ91142.1 - 7.6e-31 107.5 0.0 1.7e-20 73.8 0.0 2.2 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family MoCF_biosynth PF00994.24 KFQ91142.1 - 1.7e-17 63.5 0.0 3.3e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain ATP_bind_3 PF01171.20 KFQ91142.1 - 0.097 12.4 0.0 2 8.2 0.0 2.1 1 1 1 2 2 2 0 PP-loop family Dynamin_M PF01031.20 KFQ91143.1 - 7.4e-109 363.4 3.0 2.2e-108 361.8 2.1 2.1 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KFQ91143.1 - 9.5e-42 142.9 0.0 2.9e-41 141.3 0.0 1.9 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KFQ91143.1 - 3.8e-27 94.3 1.7 1e-26 92.9 1.7 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain PH PF00169.29 KFQ91143.1 - 5.1e-14 52.7 0.6 1.2e-13 51.5 0.6 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFQ91143.1 - 0.13 12.7 2.3 0.72 10.3 1.4 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain DZF PF07528.14 KFQ91144.1 - 1.8e-105 352.0 0.0 3.1e-105 351.3 0.0 1.4 1 0 0 1 1 1 1 DZF domain dsrm PF00035.26 KFQ91144.1 - 6.9e-26 90.7 0.1 5e-13 49.6 0.1 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KFQ91144.1 - 0.00055 20.1 0.6 1.2 9.4 0.1 3.4 2 2 0 2 2 2 2 double strand RNA binding domain from DEAD END PROTEIN 1 BSP_II PF05432.11 KFQ91144.1 - 0.0068 16.1 0.0 0.0068 16.1 0.0 1.8 3 0 0 3 3 3 1 Bone sialoprotein II (BSP-II) Choline_transpo PF04515.12 KFQ91145.1 - 1.2e-108 363.1 34.0 1.2e-108 363.1 34.0 2.6 3 0 0 3 3 3 2 Plasma-membrane choline transporter BUD22 PF09073.10 KFQ91146.1 - 4.1e-10 39.6 39.2 1.2e-08 34.8 8.9 2.2 1 1 1 2 2 2 2 BUD22 FRD2 PF03197.13 KFQ91146.1 - 0.1 12.9 2.2 0.21 11.9 2.2 1.5 1 0 0 1 1 1 0 Bacteriophage FRD2 protein Lysyl_oxidase PF01186.17 KFQ91147.1 - 5.3e-95 316.9 4.2 5.9e-95 316.7 4.2 1.0 1 0 0 1 1 1 1 Lysyl oxidase CARDB PF07705.11 KFQ91147.1 - 0.011 15.9 0.0 0.071 13.4 0.0 2.1 2 0 0 2 2 2 0 CARDB BsuPI PF12690.7 KFQ91147.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Intracellular proteinase inhibitor zf-C2HC_2 PF13913.6 KFQ91149.1 - 2.9e-12 46.1 15.2 2.1e-07 30.6 0.7 2.7 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 KFQ91149.1 - 0.0042 17.8 5.6 4.6 8.3 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFQ91149.1 - 0.016 15.6 6.2 0.4 11.2 0.3 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type Vps36-NZF-N PF16988.5 KFQ91149.1 - 0.22 11.0 4.5 0.3 10.5 0.5 2.5 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C2HC_2 PF13913.6 KFQ91150.1 - 4.2e-21 74.4 4.8 1.5e-11 43.9 0.3 2.7 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 KFQ91150.1 - 0.00019 22.0 4.7 0.19 12.6 0.2 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFQ91150.1 - 0.011 16.2 2.6 0.45 11.1 0.0 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type Sgf11 PF08209.11 KFQ91150.1 - 0.027 14.0 0.3 3.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C2H2_6 PF13912.6 KFQ91150.1 - 0.05 13.6 0.2 3.9 7.6 0.0 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger c-SKI_SMAD_bind PF08782.10 KFQ91150.1 - 0.05 13.8 0.2 0.25 11.6 0.0 1.9 2 0 0 2 2 2 0 c-SKI Smad4 binding domain zf-BED PF02892.15 KFQ91150.1 - 0.093 12.8 2.3 3.8 7.6 0.3 2.5 3 0 0 3 3 3 0 BED zinc finger DUF2318 PF10080.9 KFQ91150.1 - 0.11 12.6 0.2 4.4 7.5 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Prok-RING_1 PF14446.6 KFQ91150.1 - 1.4 8.9 5.4 3.8 7.5 0.2 2.4 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 SNCAIP_SNCA_bd PF16700.5 KFQ91151.1 - 2.9e-24 84.5 8.5 9.1e-24 82.9 8.5 1.9 1 0 0 1 1 1 1 Synphilin-1 alpha-Synuclein-binding domain Ank_4 PF13637.6 KFQ91151.1 - 1e-14 54.7 0.2 5.5e-06 26.8 0.0 3.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFQ91151.1 - 1.9e-14 54.0 1.3 2.4e-07 31.2 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFQ91151.1 - 1.2e-12 47.8 0.2 0.00029 21.1 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KFQ91151.1 - 1.5e-06 28.4 2.7 0.00036 20.8 0.2 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFQ91151.1 - 9.3e-05 22.6 0.3 0.53 11.0 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Vps5 PF09325.10 KFQ91152.1 - 2.9e-84 282.3 18.8 2.9e-84 282.3 18.8 1.4 2 0 0 2 2 1 1 Vps5 C terminal like PX PF00787.24 KFQ91152.1 - 3.9e-30 104.1 0.3 8e-29 99.9 0.1 2.4 2 0 0 2 2 2 1 PX domain Sorting_nexin PF03700.13 KFQ91152.1 - 2.9e-16 60.2 3.1 8.2e-16 58.7 3.1 1.8 1 0 0 1 1 1 1 Sorting nexin, N-terminal domain Spc7 PF08317.11 KFQ91152.1 - 0.0017 17.3 16.5 0.046 12.6 3.5 2.4 2 0 0 2 2 2 2 Spc7 kinetochore protein BAR_3_WASP_bdg PF10456.9 KFQ91152.1 - 0.027 13.9 7.2 0.84 9.1 7.2 2.5 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein DUF4618 PF15397.6 KFQ91152.1 - 0.16 11.4 13.4 0.11 11.9 1.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) DUF241 PF03087.14 KFQ91152.1 - 0.24 11.2 10.7 0.084 12.7 0.9 2.7 1 1 2 3 3 3 0 Arabidopsis protein of unknown function DUF3138 PF11336.8 KFQ91152.1 - 0.27 9.8 4.8 0.42 9.2 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) BLOC1_2 PF10046.9 KFQ91152.1 - 0.34 11.3 14.4 0.19 12.1 1.0 3.7 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3775 PF12616.8 KFQ91152.1 - 0.48 10.5 2.9 0.59 10.2 0.0 2.7 3 0 0 3 3 1 0 Protein of unknown function (DUF3775) HMMR_N PF15905.5 KFQ91152.1 - 0.61 9.5 17.5 0.064 12.7 0.8 2.4 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Csm2_III-A PF03750.13 KFQ91152.1 - 1.6 9.6 9.0 1.1 10.1 1.8 3.1 2 1 1 3 3 3 0 Csm2 Type III-A DUF2203 PF09969.9 KFQ91152.1 - 1.7 9.4 10.3 4.8 7.9 1.6 3.0 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) HR1 PF02185.16 KFQ91152.1 - 2.1 8.6 13.4 0.89 9.7 0.6 3.5 3 0 0 3 3 3 0 Hr1 repeat Exonuc_VII_L PF02601.15 KFQ91152.1 - 2.6 7.5 18.7 0.64 9.5 6.5 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit GrpE PF01025.19 KFQ91152.1 - 2.9 7.5 17.5 0.27 10.9 6.1 2.6 2 0 0 2 2 2 0 GrpE Seryl_tRNA_N PF02403.22 KFQ91152.1 - 3.3 8.0 15.3 9.2 6.6 3.3 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Allexi_40kDa PF05549.11 KFQ91152.1 - 3.4 7.1 7.9 0.62 9.5 0.7 2.6 2 1 1 3 3 3 0 Allexivirus 40kDa protein Tropomyosin PF00261.20 KFQ91152.1 - 3.8 6.8 17.3 0.056 12.8 4.3 2.4 2 0 0 2 2 2 0 Tropomyosin DHR10 PF18595.1 KFQ91152.1 - 3.8 7.6 20.3 1.6 8.8 4.4 3.3 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain Sec34 PF04136.15 KFQ91152.1 - 5.1 7.0 12.9 7.3 6.5 4.5 3.1 2 1 0 2 2 2 0 Sec34-like family Phage_HK97_TLTM PF06120.11 KFQ91152.1 - 6.5 5.9 13.1 6.8 5.8 2.2 2.2 2 0 0 2 2 2 0 Tail length tape measure protein FlaC_arch PF05377.11 KFQ91152.1 - 6.5 7.2 6.7 52 4.3 0.2 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) PX PF00787.24 KFQ91154.1 - 4.7e-14 52.3 3.3 1.4e-13 50.8 2.6 1.8 1 1 1 2 2 2 2 PX domain DUF99 PF01949.16 KFQ91154.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF99 Pro_isomerase PF00160.21 KFQ91155.1 - 1e-45 155.9 0.1 1.2e-45 155.7 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-C2H2 PF00096.26 KFQ91156.1 - 3.6e-13 49.2 20.0 2e-05 24.8 0.1 4.3 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ91156.1 - 1.8e-10 40.7 17.4 0.00013 22.5 1.5 4.5 5 0 0 5 5 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFQ91156.1 - 2.6e-10 40.2 14.7 0.0016 18.8 0.2 4.7 4 0 0 4 4 4 3 Zinc-finger double domain SET PF00856.28 KFQ91156.1 - 2e-07 31.5 0.1 8.6e-06 26.2 0.1 2.3 1 1 0 1 1 1 1 SET domain zf-C2H2_jaz PF12171.8 KFQ91156.1 - 0.00036 20.7 0.3 0.04 14.2 0.0 3.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KFQ91156.1 - 0.024 15.1 5.4 2.6 8.6 0.0 3.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 KFQ91156.1 - 0.035 13.8 1.1 0.035 13.8 1.1 3.9 4 0 0 4 4 4 0 C2H2-type zinc-finger domain UPF0113_N PF17833.1 KFQ91156.1 - 0.15 12.6 0.0 0.55 10.8 0.0 1.8 2 0 0 2 2 2 0 UPF0113 Pre-PUA domain DUF629 PF04780.12 KFQ91156.1 - 0.26 9.8 11.1 1.7 7.0 2.9 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF629) zf-C2H2_11 PF16622.5 KFQ91156.1 - 0.39 10.5 11.0 0.6 9.9 0.1 3.8 3 0 0 3 3 3 0 zinc-finger C2H2-type PyrI_C PF02748.15 KFQ91156.1 - 0.39 10.7 2.9 3.5 7.6 0.0 3.0 3 1 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2HC_2 PF13913.6 KFQ91156.1 - 0.42 10.6 0.0 0.42 10.6 0.0 3.7 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-LYAR PF08790.11 KFQ91156.1 - 0.75 9.8 5.9 11 6.1 0.3 3.7 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-CHCC PF10276.9 KFQ91156.1 - 3.2 7.9 7.2 0.66 10.1 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger domain Zn_ribbon_SprT PF17283.2 KFQ91156.1 - 3.6 7.6 12.4 0.82 9.6 1.9 3.8 4 0 0 4 4 4 0 SprT-like zinc ribbon domain zf-BED PF02892.15 KFQ91156.1 - 4 7.5 10.4 5.3 7.2 0.3 3.8 3 1 1 4 4 3 0 BED zinc finger zf-C2H2_2 PF12756.7 KFQ91156.1 - 4.3 7.7 8.3 24 5.4 0.0 3.7 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 KFQ91156.1 - 5.1 7.5 13.5 3.6 8.0 0.0 4.0 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF3668 PF12416.8 KFQ91157.1 - 1e-92 310.0 0.0 1e-92 310.0 0.0 2.7 2 0 0 2 2 2 1 Cep120 protein C2 PF00168.30 KFQ91157.1 - 1.4e-08 34.9 0.0 0.0089 16.3 0.0 3.5 3 0 0 3 3 3 3 C2 domain TMEM174 PF15029.6 KFQ91158.1 - 1.5e-98 329.2 0.1 1.7e-98 329.0 0.1 1.0 1 0 0 1 1 1 1 Transmembrane protein 174 PDZ PF00595.24 KFQ91159.1 - 3.6e-52 174.6 7.2 3.2e-22 78.7 0.4 3.3 3 0 0 3 3 3 3 PDZ domain Guanylate_kin PF00625.21 KFQ91159.1 - 1.6e-21 76.8 0.1 2.7e-21 76.1 0.1 1.3 1 0 0 1 1 1 1 Guanylate kinase PDZ_6 PF17820.1 KFQ91159.1 - 9.4e-21 73.4 2.7 1.8e-09 37.3 0.1 3.3 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 KFQ91159.1 - 5.9e-16 58.6 3.7 6.1e-07 29.7 0.1 3.3 3 0 0 3 3 3 3 PDZ domain PDZ_assoc PF10600.9 KFQ91159.1 - 1.6e-14 54.4 1.8 6.6e-14 52.5 1.8 2.1 1 0 0 1 1 1 1 PDZ-associated domain of NMDA receptors Tecti-min-caps PF09300.10 KFQ91159.1 - 0.017 15.2 0.0 0.017 15.2 0.0 2.0 2 0 0 2 2 2 0 Tectiviridae, minor capsid PDZ_4 PF17816.1 KFQ91159.1 - 0.032 14.6 0.4 4.8 7.6 0.0 3.2 3 0 0 3 3 3 0 PDZ domain Tricorn_PDZ PF14685.6 KFQ91159.1 - 0.041 13.8 2.4 2.2 8.3 0.0 3.3 3 0 0 3 3 3 0 Tricorn protease PDZ domain Haspin_kinase PF12330.8 KFQ91163.1 - 3.4 6.5 6.3 0.4 9.6 0.9 1.8 1 1 1 2 2 2 0 Haspin like kinase domain FAM178 PF14816.6 KFQ91164.1 - 3.7e-150 500.1 7.9 5e-150 499.6 7.9 1.1 1 0 0 1 1 1 1 Family of unknown function, FAM178 8TM_micro PF17028.5 KFQ91164.1 - 1.4 8.6 6.1 0.15 11.8 0.3 2.1 3 0 0 3 3 3 0 8TM Microsporidial transmembrane domain Sema PF01403.19 KFQ91165.1 - 4.7e-148 493.5 0.0 6.7e-148 493.0 0.0 1.2 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 KFQ91165.1 - 5.3e-05 23.7 6.0 0.00021 21.7 6.0 2.1 1 0 0 1 1 1 1 Plexin repeat Ig_3 PF13927.6 KFQ91165.1 - 0.0019 18.8 0.0 0.0077 16.8 0.0 2.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFQ91165.1 - 0.0026 17.9 0.0 0.0066 16.6 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFQ91165.1 - 0.0034 17.7 0.0 0.0075 16.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain OSTbeta PF15048.6 KFQ91165.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein PSI_integrin PF17205.3 KFQ91165.1 - 0.34 10.7 3.7 0.95 9.3 3.7 1.8 1 0 0 1 1 1 0 Integrin plexin domain AAA_25 PF13481.6 KFQ91167.1 - 3.2e-13 49.7 0.0 5.4e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFQ91167.1 - 5.3e-06 26.9 0.0 1.1e-05 25.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 KFQ91167.1 - 2.4e-05 23.8 0.0 3.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain T2SSE PF00437.20 KFQ91167.1 - 6.6e-05 22.1 0.0 8.2e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 KFQ91167.1 - 0.00028 20.5 0.0 0.00065 19.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KFQ91167.1 - 0.00073 20.1 0.0 0.0011 19.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KFQ91167.1 - 0.0021 17.5 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.6 KFQ91167.1 - 0.0075 16.5 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFQ91167.1 - 0.013 15.6 0.0 0.029 14.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFQ91167.1 - 0.024 14.4 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KFQ91167.1 - 0.041 13.9 0.0 0.084 12.9 0.0 1.5 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 KFQ91167.1 - 0.046 13.2 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.6 KFQ91167.1 - 0.053 13.9 0.0 0.098 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFQ91167.1 - 0.06 12.9 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KFQ91167.1 - 0.071 13.6 0.1 0.13 12.8 0.1 1.4 1 0 0 1 1 1 0 ABC transporter cobW PF02492.19 KFQ91167.1 - 0.074 12.6 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 KFQ91167.1 - 0.099 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 KFQ91167.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase NTPase_1 PF03266.15 KFQ91167.1 - 0.22 11.4 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_11 PF13086.6 KFQ91167.1 - 0.26 11.0 0.0 0.38 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain PDZ PF00595.24 KFQ91168.1 - 4.2e-12 46.2 0.2 4.4e-12 46.2 0.2 1.1 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFQ91168.1 - 1.2e-05 25.0 0.3 4.7e-05 23.1 0.3 1.8 1 1 0 1 1 1 1 PDZ domain Mtc PF03820.17 KFQ91169.1 - 4.7e-152 505.5 0.2 5.3e-152 505.3 0.2 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Ig_3 PF13927.6 KFQ91170.1 - 1.4e-14 54.5 0.0 2.1e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ91170.1 - 4.3e-14 52.3 0.0 6.1e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain IGFBP PF00219.18 KFQ91170.1 - 8.6e-09 35.9 20.6 8.6e-09 35.9 20.6 2.1 2 0 0 2 2 2 1 Insulin-like growth factor binding protein Ig_2 PF13895.6 KFQ91170.1 - 6.4e-07 29.6 0.0 1.4e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFQ91170.1 - 2.7e-06 27.5 0.0 7.6e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Kazal_1 PF00050.21 KFQ91170.1 - 4.2e-05 23.5 0.3 4.2e-05 23.5 0.3 2.0 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KFQ91170.1 - 6.4e-05 23.0 11.0 0.00013 22.1 0.6 2.7 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain V-set PF07686.17 KFQ91170.1 - 0.0021 18.2 0.0 0.007 16.5 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin V-set domain Homeodomain PF00046.29 KFQ91171.1 - 1.5e-20 72.8 6.8 2.6e-20 72.0 6.8 1.4 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 KFQ91171.1 - 0.0023 17.4 0.2 0.0043 16.5 0.2 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 KFQ91171.1 - 0.032 14.2 0.3 0.077 12.9 0.3 1.6 1 0 0 1 1 1 0 Homeobox KN domain WD40 PF00400.32 KFQ91172.1 - 9.8e-40 133.8 18.6 2.3e-06 28.2 0.2 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Beta-TrCP_D PF12125.8 KFQ91172.1 - 3.7e-24 84.3 4.0 7.3e-24 83.4 4.0 1.5 1 0 0 1 1 1 1 D domain of beta-TrCP F-box-like PF12937.7 KFQ91172.1 - 1.7e-10 40.6 0.5 5e-10 39.1 0.2 2.0 1 1 1 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 KFQ91172.1 - 2.6e-09 37.2 2.1 0.06 13.7 0.0 4.5 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 KFQ91172.1 - 6.7e-07 29.0 0.0 1.8e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 KFQ91172.1 - 5.5e-06 25.9 0.3 0.0042 16.5 0.2 2.4 1 1 1 2 2 2 2 WD40-like domain Nup160 PF11715.8 KFQ91172.1 - 6.5e-05 21.8 6.8 0.094 11.3 0.2 4.6 3 1 2 5 5 5 2 Nucleoporin Nup120/160 F-box_5 PF18511.1 KFQ91172.1 - 0.0062 16.1 0.1 0.019 14.6 0.1 1.9 1 0 0 1 1 1 1 F-box eIF2A PF08662.11 KFQ91172.1 - 0.038 13.8 0.0 4.4 7.1 0.0 2.5 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF4508 PF14969.6 KFQ91172.1 - 0.065 13.5 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) DUF5046 PF16465.5 KFQ91172.1 - 0.072 12.5 0.2 5.5 6.3 0.1 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF5046) 120_Rick_ant PF12574.8 KFQ91172.1 - 0.12 11.5 0.1 0.58 9.3 0.0 1.9 1 1 1 2 2 2 0 120 KDa Rickettsia surface antigen Sugar_tr PF00083.24 KFQ91173.1 - 1.9e-105 353.4 22.0 2.1e-105 353.2 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFQ91173.1 - 2.3e-16 59.7 54.3 5.1e-15 55.2 25.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily BChl_A PF02327.17 KFQ91173.1 - 0.038 12.8 0.0 0.053 12.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriochlorophyll A protein YfhO PF09586.10 KFQ91173.1 - 0.43 8.7 2.6 0.62 8.2 2.6 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO RDD PF06271.12 KFQ91173.1 - 2.4 8.3 9.1 0.14 12.4 0.5 2.9 2 1 0 2 2 2 0 RDD family DNA_pol_B_palm PF14792.6 KFQ91174.1 - 1.4e-35 121.9 0.0 5.6e-35 120.0 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 KFQ91174.1 - 8.9e-22 76.7 0.1 1.5e-20 72.7 0.3 2.5 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 KFQ91174.1 - 1.1e-20 73.6 0.0 2.2e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 KFQ91174.1 - 6.5e-19 68.1 0.1 1.5e-18 66.9 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 KFQ91174.1 - 9.1e-05 23.0 0.0 0.12 13.0 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 KFQ91174.1 - 0.02 15.2 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain HHH PF00633.23 KFQ91174.1 - 0.027 14.3 0.0 0.067 13.1 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Cdd1 PF11731.8 KFQ91174.1 - 0.045 14.0 0.0 11 6.4 0.0 2.7 2 0 0 2 2 2 0 Pathogenicity locus IMS_HHH PF11798.8 KFQ91174.1 - 0.1 13.0 0.2 0.33 11.4 0.1 2.0 2 0 0 2 2 2 0 IMS family HHH motif zf-LYAR PF08790.11 KFQ91174.1 - 0.22 11.4 1.7 0.35 10.8 0.3 2.1 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger DPCD PF14913.6 KFQ91175.1 - 1.3e-90 301.9 0.5 1.5e-90 301.7 0.5 1.0 1 0 0 1 1 1 1 DPCD protein family Mcl1_mid PF12341.8 KFQ91175.1 - 0.029 13.7 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KFQ91176.1 - 8.5e-14 51.7 18.9 0.00024 21.8 0.1 6.7 5 1 0 5 5 5 4 WD domain, G-beta repeat F-box-like PF12937.7 KFQ91176.1 - 8.6e-11 41.6 2.2 1.2e-10 41.1 1.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFQ91176.1 - 1.1e-05 25.2 0.7 3e-05 23.8 0.7 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KFQ91176.1 - 0.00067 19.5 0.8 0.17 11.8 0.0 2.7 2 0 0 2 2 2 2 F-box FGF PF00167.18 KFQ91177.1 - 1.1e-42 145.1 1.0 1.6e-42 144.6 1.0 1.2 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.13 KFQ91177.1 - 0.063 13.5 0.0 0.11 12.8 0.0 1.5 1 1 0 1 1 1 0 Fascin domain TLP1_add_C PF18313.1 KFQ91177.1 - 0.19 11.7 0.4 10 6.1 0.0 2.4 2 1 0 2 2 2 0 Thiolase-like protein type 1 additional C-terminal domain Nucleoplasmin PF03066.15 KFQ91178.1 - 1.1e-33 115.7 0.0 1.4e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Nucleoplasmin/nucleophosmin domain Nitrophorin PF02087.15 KFQ91178.1 - 0.0011 19.0 0.1 0.0013 18.8 0.1 1.1 1 0 0 1 1 1 1 Nitrophorin EF-hand_7 PF13499.6 KFQ91179.1 - 1.2e-23 83.3 5.6 2.5e-16 59.9 0.5 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFQ91179.1 - 9.8e-22 74.8 9.4 2.1e-07 30.0 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFQ91179.1 - 1.9e-18 64.7 7.6 8.9e-06 25.2 0.1 4.2 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KFQ91179.1 - 2.2e-17 61.7 3.9 1.5e-05 24.3 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KFQ91179.1 - 3.6e-15 55.5 4.1 1.1e-06 28.4 0.1 3.4 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFQ91179.1 - 2.5e-06 27.8 1.4 0.002 18.5 0.7 3.3 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFQ91179.1 - 0.00031 20.6 2.1 0.05 13.5 0.1 2.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFQ91179.1 - 0.0074 16.6 0.2 0.47 10.8 0.1 2.8 2 1 0 2 2 2 1 EF-hand domain UPF0223 PF05256.12 KFQ91179.1 - 0.0077 16.5 1.1 1 9.7 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0223) Dockerin_1 PF00404.18 KFQ91179.1 - 0.06 13.6 1.4 3.2 8.0 0.4 2.8 1 1 1 2 2 2 0 Dockerin type I domain Caleosin PF05042.13 KFQ91179.1 - 0.11 12.5 5.4 5.1 7.0 0.2 3.4 1 1 2 3 3 3 0 Caleosin related protein DUF1741 PF08427.10 KFQ91180.1 - 3.1e-84 282.3 6.1 5.7e-84 281.4 6.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) HPS6 PF15702.5 KFQ91181.1 - 0 1079.0 7.3 0 1078.8 7.3 1.0 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 6 protein Prominin PF05478.11 KFQ91182.1 - 2.5e-107 359.8 0.1 2.8e-107 359.7 0.1 1.0 1 0 0 1 1 1 1 Prominin Baculo_PEP_C PF04513.12 KFQ91182.1 - 0.02 15.0 0.9 0.038 14.0 0.3 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LPD22 PF18834.1 KFQ91182.1 - 0.059 13.6 0.0 0.29 11.4 0.0 2.0 1 1 0 1 1 1 0 Large polyvalent protein associated domain 22 TBD PF12845.7 KFQ91182.1 - 0.078 12.9 0.0 3.2 7.7 0.0 3.0 3 0 0 3 3 3 0 TBD domain SMC_ScpA PF02616.14 KFQ91182.1 - 0.21 11.5 2.5 0.34 10.8 2.0 1.7 1 1 0 1 1 1 0 Segregation and condensation protein ScpA GrpE PF01025.19 KFQ91182.1 - 0.25 11.0 4.2 0.79 9.4 4.2 1.8 1 1 0 1 1 1 0 GrpE DUF2682 PF10909.8 KFQ91182.1 - 0.28 11.7 1.1 0.81 10.2 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2682) Prominin PF05478.11 KFQ91183.1 - 0.00011 20.4 0.0 0.00012 20.2 0.0 1.0 1 0 0 1 1 1 1 Prominin LIM_bind PF01803.16 KFQ91184.1 - 3.5e-54 183.9 9.0 3.1e-42 144.8 1.6 2.7 2 1 1 3 3 3 2 LIM-domain binding protein LID PF17916.1 KFQ91184.1 - 1.7e-18 65.9 2.5 3e-18 65.2 2.5 1.4 1 0 0 1 1 1 1 LIM interaction domain (LID) RRM_1 PF00076.22 KFQ91186.1 - 8.5e-09 35.1 0.0 1.6e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Apt1 PF10351.9 KFQ91186.1 - 7.1 5.4 17.1 13 4.5 17.1 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain HTH_psq PF05225.16 KFQ91187.1 - 1.4e-14 53.5 0.1 3.7e-14 52.2 0.0 1.8 2 0 0 2 2 2 1 helix-turn-helix, Psq domain LRR_8 PF13855.6 KFQ91188.1 - 5.4e-97 317.5 82.0 4.3e-14 52.0 0.0 10.0 4 4 6 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 KFQ91188.1 - 8.5e-41 137.3 51.6 2e-06 28.0 0.1 11.2 10 1 1 11 11 11 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFQ91188.1 - 8.8e-37 125.9 6.3 4.1e-10 39.7 0.1 5.1 4 1 0 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFQ91188.1 - 5.3e-23 81.4 15.6 0.0022 17.5 0.0 6.1 4 2 2 6 6 6 6 Leucine-rich repeat EGF PF00008.27 KFQ91188.1 - 2.7e-22 78.7 97.4 4.3e-08 33.3 5.9 9.0 10 0 0 10 10 8 5 EGF-like domain Laminin_G_2 PF02210.24 KFQ91188.1 - 1.6e-21 77.2 0.1 2.8e-21 76.4 0.1 1.4 1 0 0 1 1 1 1 Laminin G domain LRRNT PF01462.18 KFQ91188.1 - 2e-21 75.2 30.4 8.2e-09 34.9 1.5 5.6 4 0 0 4 4 4 3 Leucine rich repeat N-terminal domain Laminin_G_1 PF00054.23 KFQ91188.1 - 7.6e-21 74.7 0.0 1.2e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain LRRCT PF01463.24 KFQ91188.1 - 9.3e-20 69.5 17.1 0.00067 20.0 0.0 7.0 6 0 0 6 6 5 4 Leucine rich repeat C-terminal domain hEGF PF12661.7 KFQ91188.1 - 2.8e-11 43.6 89.5 4.6e-05 23.9 3.3 9.9 10 0 0 10 10 8 5 Human growth factor-like EGF LRR_1 PF00560.33 KFQ91188.1 - 4.9e-07 29.4 46.5 0.53 11.0 0.0 13.9 15 2 1 16 16 13 5 Leucine Rich Repeat TPKR_C2 PF16920.5 KFQ91188.1 - 0.00022 21.3 19.5 0.029 14.5 0.4 6.4 6 0 0 6 6 5 2 Tyrosine-protein kinase receptor C2 Ig-like domain EGF_CA PF07645.15 KFQ91188.1 - 0.0017 18.5 7.5 0.0017 18.5 7.5 8.5 7 1 2 9 9 7 1 Calcium-binding EGF domain Laminin_G_3 PF13385.6 KFQ91188.1 - 0.18 11.9 0.2 0.44 10.7 0.2 1.5 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily RhoGAP PF00620.27 KFQ91189.1 - 9.8e-36 122.9 0.4 9.8e-36 122.9 0.4 1.7 2 0 0 2 2 2 1 RhoGAP domain NUC173 PF08161.12 KFQ91190.1 - 2.1e-77 259.4 0.0 2.2e-73 246.3 0.0 3.4 3 0 0 3 3 3 2 NUC173 domain DUF3136 PF11334.8 KFQ91190.1 - 0.077 12.8 0.1 17 5.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) HEAT PF02985.22 KFQ91190.1 - 0.097 13.0 0.0 53 4.5 0.1 4.1 2 0 0 2 2 2 0 HEAT repeat RPN7 PF10602.9 KFQ91190.1 - 0.19 11.4 2.7 34 4.1 0.1 4.1 4 1 0 4 4 4 0 26S proteasome subunit RPN7 Ribosomal_L37 PF08561.10 KFQ91190.1 - 0.49 10.9 5.1 1.4 9.5 5.1 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 His_Phos_1 PF00300.22 KFQ91191.1 - 9.9e-19 67.8 0.0 3.5e-10 39.9 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) EXOSC1 PF10447.9 KFQ91192.1 - 2.6e-15 57.0 0.5 3.6e-12 46.9 0.2 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KFQ91192.1 - 9.7e-05 22.1 0.0 0.00027 20.7 0.0 1.8 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region DHHC PF01529.20 KFQ91193.1 - 9.1e-31 106.7 12.5 9.1e-31 106.7 12.5 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase MMS19_C PF12460.8 KFQ91194.1 - 2.4e-115 386.1 0.7 2.4e-115 386.1 0.7 3.4 2 1 0 2 2 2 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 KFQ91194.1 - 3.8e-90 302.0 10.5 1e-89 300.6 0.1 4.0 4 1 0 4 4 4 2 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.6 KFQ91194.1 - 0.00012 22.4 13.2 0.015 15.7 1.7 5.8 4 2 3 7 7 7 3 HEAT repeats MIF4G PF02854.19 KFQ91194.1 - 0.011 15.4 0.0 0.038 13.6 0.0 1.9 2 0 0 2 2 2 0 MIF4G domain ParcG PF10274.9 KFQ91194.1 - 0.13 12.3 0.3 5.9 7.0 0.1 2.9 2 0 0 2 2 2 0 Parkin co-regulated protein HEAT_EZ PF13513.6 KFQ91194.1 - 1.4 9.5 20.2 0.51 10.9 0.1 7.6 8 1 1 9 9 9 0 HEAT-like repeat UBD PF16455.5 KFQ91195.1 - 9.6e-38 128.6 0.0 1.8e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 KFQ91195.1 - 2.2e-14 53.0 0.1 3.9e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KFQ91195.1 - 0.00042 20.1 0.0 0.0006 19.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ank_4 PF13637.6 KFQ91196.1 - 0.00016 22.1 0.0 0.00026 21.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFQ91196.1 - 0.0013 19.3 0.0 0.002 18.7 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFQ91196.1 - 0.0016 18.8 0.0 0.063 13.8 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KFQ91196.1 - 0.032 14.8 0.0 0.33 11.6 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat DHDPS PF00701.22 KFQ91197.1 - 3.5e-52 176.9 0.0 4.2e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MORN PF02493.20 KFQ91198.1 - 7.6e-28 94.7 20.1 3.4e-08 32.9 0.3 5.7 6 0 0 6 6 6 4 MORN repeat HCBP_related PF06594.11 KFQ91198.1 - 0.054 13.5 1.0 0.2 11.6 0.1 2.3 3 0 0 3 3 3 0 Haemolysin-type calcium binding protein related domain Rib PF08428.10 KFQ91198.1 - 0.055 13.5 0.1 20 5.2 0.0 2.9 3 0 0 3 3 3 0 Rib/alpha-like repeat PI3_PI4_kinase PF00454.27 KFQ91199.1 - 8.6e-62 209.2 0.0 1e-61 208.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase MARVEL PF01284.23 KFQ91200.1 - 7.7e-07 29.2 10.1 8.9e-07 29.0 10.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain FYVE PF01363.21 KFQ91201.1 - 3.6e-08 33.4 11.0 3.6e-08 33.4 11.0 2.2 4 0 0 4 4 4 1 FYVE zinc finger FYVE_2 PF02318.16 KFQ91201.1 - 0.00016 21.9 10.6 0.00018 21.7 6.8 2.3 2 0 0 2 2 2 1 FYVE-type zinc finger Reticulon PF02453.17 KFQ91201.1 - 0.00083 19.4 1.3 0.43 10.5 0.1 2.2 2 0 0 2 2 2 2 Reticulon Pex24p PF06398.11 KFQ91201.1 - 0.022 13.7 0.1 0.36 9.8 0.0 2.0 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin DUF639 PF04842.12 KFQ91201.1 - 0.097 12.1 0.8 12 5.2 0.0 2.3 1 1 0 2 2 2 0 Plant protein of unknown function (DUF639) Erf4 PF10256.9 KFQ91202.1 - 6.9e-33 113.2 0.0 7.9e-33 113.0 0.0 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family VCBS PF13517.6 KFQ91203.1 - 3.6e-30 104.3 15.0 1.1e-10 41.9 1.1 5.2 4 1 1 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella UnbV_ASPIC PF07593.12 KFQ91203.1 - 8.9e-14 51.2 0.0 1.9e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 ASPIC and UnbV FG-GAP PF01839.23 KFQ91203.1 - 3.7e-12 46.1 19.0 0.0029 17.7 0.4 5.3 5 0 0 5 5 5 3 FG-GAP repeat EGF_CA PF07645.15 KFQ91203.1 - 9.7e-11 41.7 7.0 9.7e-11 41.7 7.0 1.8 2 0 0 2 2 2 1 Calcium-binding EGF domain cEGF PF12662.7 KFQ91203.1 - 0.011 15.6 9.1 0.26 11.3 1.7 2.8 2 0 0 2 2 2 0 Complement Clr-like EGF-like Imm75 PF15660.6 KFQ91203.1 - 0.13 12.6 0.1 0.31 11.3 0.1 1.7 1 0 0 1 1 1 0 Putative Immunity protein 75 Dockerin_1 PF00404.18 KFQ91203.1 - 0.29 11.4 3.7 33 4.8 0.1 3.8 4 0 0 4 4 4 0 Dockerin type I domain NCBP3 PF10309.9 KFQ91204.1 - 7.4e-05 22.5 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 KFQ91204.1 - 0.006 16.6 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 RNA binding domain SRCR PF00530.18 KFQ91205.1 - 1.7e-99 326.9 29.1 2.6e-29 101.7 5.5 4.1 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFQ91205.1 - 6.5e-21 74.7 16.9 3.7e-05 24.2 0.2 4.3 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFQ91205.1 - 1.7e-11 44.6 3.4 0.062 13.8 0.0 4.4 4 0 0 4 4 4 3 Hepsin, SRCR domain ABC_trans_aux PF03886.13 KFQ91205.1 - 0.13 11.9 0.1 1.2 8.6 0.0 2.5 3 0 0 3 3 3 0 ABC-type transport auxiliary lipoprotein component YecR PF13992.6 KFQ91205.1 - 0.31 11.3 5.6 11 6.4 0.1 3.6 3 1 1 4 4 4 0 YecR-like lipoprotein GDI PF00996.18 KFQ91206.1 - 0.037 12.5 0.0 0.054 12.0 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor GMC_oxred_N PF00732.19 KFQ91206.1 - 0.07 12.5 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 GMC oxidoreductase Mon1 PF03164.14 KFQ91207.1 - 0.054 12.5 0.0 8.4 5.3 0.0 2.4 2 0 0 2 2 2 0 Trafficking protein Mon1 DUF2535 PF10751.9 KFQ91207.1 - 0.15 12.6 0.0 0.51 10.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2535) Glyco_hydro_79n PF03662.14 KFQ91208.1 - 4.8e-22 78.3 0.4 1.7e-21 76.5 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 79, N-terminal domain Aminotran_1_2 PF00155.21 KFQ91210.1 - 6.6e-88 295.3 0.0 7.8e-88 295.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II GDA1_CD39 PF01150.17 KFQ91211.1 - 9.7e-68 228.8 0.0 1.3e-67 228.3 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family COX15-CtaA PF02628.15 KFQ91212.1 - 8.3e-104 347.1 4.3 9.4e-104 347.0 4.3 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF4807 PF16065.5 KFQ91212.1 - 0.053 13.2 0.1 0.12 12.0 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4807) CutC PF03932.14 KFQ91213.1 - 1.5e-56 191.1 0.0 3.1e-56 190.1 0.0 1.4 2 0 0 2 2 2 1 CutC family BAR PF03114.18 KFQ91214.1 - 1.1e-41 143.1 3.5 1.6e-41 142.5 3.5 1.2 1 0 0 1 1 1 1 BAR domain RhoGEF PF00621.20 KFQ91214.1 - 3.2e-14 53.6 0.0 3.2e-14 53.6 0.0 2.4 2 1 0 2 2 2 1 RhoGEF domain SH3_1 PF00018.28 KFQ91214.1 - 1.6e-11 43.6 0.0 1.5e-07 30.9 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KFQ91214.1 - 1.8e-11 43.6 0.1 5.8e-06 25.9 0.0 2.8 3 0 0 3 3 3 2 Variant SH3 domain SH3_9 PF14604.6 KFQ91214.1 - 1.8e-09 37.3 0.0 4.9e-07 29.5 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 KFQ91214.1 - 0.11 12.8 0.1 0.6 10.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial SH3 domain RhoGEF PF00621.20 KFQ91215.1 - 6.1e-20 72.2 0.6 7.2e-20 72.0 0.6 1.0 1 0 0 1 1 1 1 RhoGEF domain Peptidase_M14 PF00246.24 KFQ91216.1 - 1.2e-80 271.4 0.1 1.5e-80 271.1 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 KFQ91216.1 - 1.3e-14 54.2 0.4 2.5e-14 53.3 0.4 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KFQ91216.1 - 1.2e-09 38.0 0.1 2.2e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 CarboxypepD_reg-like domain AstE_AspA PF04952.14 KFQ91216.1 - 0.028 13.5 0.2 0.069 12.2 0.2 1.7 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family GDA1_CD39 PF01150.17 KFQ91217.1 - 5.2e-136 453.7 0.1 6.1e-136 453.4 0.1 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DDE_Tnp_IS1595 PF12762.7 KFQ91217.1 - 0.15 12.1 0.1 0.26 11.3 0.1 1.3 1 0 0 1 1 1 0 ISXO2-like transposase domain LRR_8 PF13855.6 KFQ91220.1 - 4.2e-15 55.3 2.6 4.2e-15 55.3 2.6 2.3 2 1 0 2 2 2 1 Leucine rich repeat 7tm_2 PF00002.24 KFQ91220.1 - 1.2e-12 47.6 7.9 2.3e-12 46.7 7.9 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 KFQ91220.1 - 3.7e-08 33.8 0.1 3.7e-08 33.8 0.1 3.4 3 0 0 3 3 3 1 GPCR proteolysis site, GPS, motif LRR_4 PF12799.7 KFQ91220.1 - 2.4e-07 30.9 9.8 5e-05 23.6 3.2 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) I-set PF07679.16 KFQ91220.1 - 3.2e-07 30.3 0.0 6.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain HRM PF02793.22 KFQ91220.1 - 5.9e-05 23.3 1.4 5.9e-05 23.3 1.4 2.5 3 0 0 3 3 3 1 Hormone receptor domain LRR_1 PF00560.33 KFQ91220.1 - 0.00077 19.7 5.5 0.17 12.5 0.1 4.4 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_5 PF13306.6 KFQ91220.1 - 0.0026 17.7 0.9 0.016 15.2 0.1 2.7 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) ig PF00047.25 KFQ91220.1 - 0.018 15.2 0.1 0.039 14.1 0.1 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Pex24p PF06398.11 KFQ91220.1 - 5.9 5.8 6.8 0.23 10.4 0.1 2.0 3 0 0 3 3 3 0 Integral peroxisomal membrane peroxin Sulfotransfer_1 PF00685.27 KFQ91221.1 - 1.7e-32 113.0 0.1 2.3e-32 112.6 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFQ91221.1 - 8.5e-13 49.2 0.0 1.8e-08 35.0 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family DNA_pol_B_thumb PF14791.6 KFQ91222.1 - 6.2e-19 67.9 0.4 1.9e-18 66.3 0.4 1.9 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 KFQ91222.1 - 9.9e-18 63.7 0.1 1.8e-17 62.9 0.1 1.4 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 KFQ91222.1 - 2.4e-12 47.0 0.0 1.3e-11 44.7 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_B_palm PF14792.6 KFQ91222.1 - 4.8e-08 33.2 0.0 1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm BRCT PF00533.26 KFQ91222.1 - 8e-05 22.9 0.0 0.0002 21.7 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.23 KFQ91222.1 - 0.0002 21.6 0.0 0.00047 20.4 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Cdd1 PF11731.8 KFQ91222.1 - 0.0051 17.0 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 Pathogenicity locus DUF3463 PF11946.8 KFQ91222.1 - 0.033 14.0 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) HHH_5 PF14520.6 KFQ91222.1 - 0.15 12.7 0.0 0.32 11.6 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain SH2 PF00017.24 KFQ91223.1 - 2.6e-11 43.4 0.1 7.8e-11 41.9 0.1 1.8 2 0 0 2 2 2 1 SH2 domain zf-C2H2 PF00096.26 KFQ91224.1 - 8.4e-06 26.0 48.7 0.091 13.3 0.3 7.6 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFQ91224.1 - 0.013 15.2 0.3 0.013 15.2 0.3 5.2 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KFQ91224.1 - 0.054 14.0 43.4 0.095 13.2 0.6 7.7 7 0 0 7 7 7 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ91224.1 - 0.1 13.5 48.1 1.9 9.6 0.3 8.2 7 0 0 7 7 7 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KFQ91224.1 - 0.11 12.2 16.8 0.45 10.2 0.5 5.4 4 1 1 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-ZPR1 PF03367.13 KFQ91224.1 - 0.57 10.0 10.0 1.3 8.9 5.3 3.1 2 0 0 2 2 2 0 ZPR1 zinc-finger domain Cyclin_C PF02984.19 KFQ91225.1 - 1.2e-19 70.5 0.4 1.2e-19 70.5 0.4 3.2 3 0 0 3 3 3 2 Cyclin, C-terminal domain Cyclin_N PF00134.23 KFQ91225.1 - 2e-19 69.6 1.4 3.9e-19 68.7 0.6 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Ni_hydr_CYTB PF01292.20 KFQ91225.1 - 0.072 12.7 0.4 0.11 12.1 0.4 1.3 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 TFIIA PF03153.13 KFQ91225.1 - 0.31 11.0 7.9 0.4 10.6 7.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PurK_C PF17769.1 KFQ91227.1 - 0.036 13.8 0.2 0.061 13.0 0.2 1.4 1 0 0 1 1 1 0 Phosphoribosylaminoimidazole carboxylase C-terminal domain DUF3535 PF12054.8 KFQ91228.1 - 1.5e-134 449.5 8.2 4.3e-131 438.1 6.3 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KFQ91228.1 - 2.4e-59 200.8 0.0 9.6e-59 198.8 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain HEAT PF02985.22 KFQ91228.1 - 1.3e-21 74.8 21.0 0.0052 16.9 0.0 13.1 12 1 0 12 12 12 6 HEAT repeat Helicase_C PF00271.31 KFQ91228.1 - 2.2e-17 63.4 0.0 6.8e-17 61.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vac14_Fab1_bd PF12755.7 KFQ91228.1 - 2.1e-11 44.2 0.1 0.015 15.9 0.0 5.5 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 KFQ91228.1 - 3e-11 43.5 3.0 0.033 14.6 0.3 6.9 5 1 2 7 7 7 5 HEAT repeats TAF6_C PF07571.13 KFQ91228.1 - 5.3e-05 23.5 0.0 3 8.3 0.0 6.4 4 1 0 5 5 5 1 TAF6 C-terminal HEAT repeat domain HEAT_EZ PF13513.6 KFQ91228.1 - 0.00013 22.4 16.1 0.0041 17.6 0.1 7.9 9 1 0 9 9 9 1 HEAT-like repeat Cnd1 PF12717.7 KFQ91228.1 - 0.0022 18.1 11.6 0.3 11.1 0.2 5.2 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 KFQ91228.1 - 0.027 14.5 2.8 0.86 9.7 0.0 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat UME PF08064.13 KFQ91228.1 - 0.39 10.6 4.1 44 4.1 0.0 5.0 4 1 0 4 4 4 0 UME (NUC010) domain RRM_7 PF16367.5 KFQ91229.1 - 9.2e-38 128.3 0.0 6.4e-36 122.4 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif CEBP_ZZ PF16366.5 KFQ91229.1 - 1.8e-20 72.9 5.8 5e-20 71.5 5.8 1.8 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 KFQ91229.1 - 1e-11 44.5 0.0 1.3e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-U1 PF06220.12 KFQ91229.1 - 0.037 13.8 0.6 0.087 12.6 0.6 1.6 1 0 0 1 1 1 0 U1 zinc finger SKG6 PF08693.10 KFQ91229.1 - 0.33 10.4 4.4 0.68 9.4 4.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain zf-B_box PF00643.24 KFQ91229.1 - 0.35 11.1 5.8 0.89 9.8 5.8 1.6 1 0 0 1 1 1 0 B-box zinc finger EPL1 PF10513.9 KFQ91229.1 - 1.4 9.3 7.8 8.5 6.7 0.2 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like RINGv PF12906.7 KFQ91230.1 - 1.5e-14 53.9 10.9 2.2e-14 53.3 10.9 1.3 1 0 0 1 1 1 1 RING-variant domain DUF2517 PF10725.9 KFQ91230.1 - 0.0011 18.7 0.1 0.003 17.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2517) zf-RING_2 PF13639.6 KFQ91230.1 - 0.0024 18.2 6.6 0.0055 17.0 6.6 1.7 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KFQ91230.1 - 0.041 14.0 5.7 0.09 13.0 5.7 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KFQ91230.1 - 0.44 10.4 6.0 0.95 9.3 6.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-CSL PF05207.13 KFQ91230.1 - 0.5 10.1 3.2 1.1 9.0 3.2 1.5 1 1 0 1 1 1 0 CSL zinc finger PHD PF00628.29 KFQ91230.1 - 1.3 9.0 8.6 2.2 8.2 8.6 1.4 1 0 0 1 1 1 0 PHD-finger Peptidase_M16_M PF16187.5 KFQ91231.1 - 2.5e-99 332.1 6.1 2.5e-99 332.1 6.1 1.7 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KFQ91231.1 - 3.8e-48 163.2 0.2 3.3e-46 157.0 0.1 2.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFQ91231.1 - 5.9e-40 137.2 0.1 5.2e-22 78.7 0.0 3.4 4 0 0 4 4 4 2 Peptidase M16 inactive domain Tn916-Xis PF09035.10 KFQ91231.1 - 0.053 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Excisionase from transposon Tn916 Kinesin PF00225.23 KFQ91232.1 - 9.1e-116 386.4 0.1 9.1e-116 386.4 0.1 3.2 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bind PF13931.6 KFQ91232.1 - 4.5e-50 169.5 2.9 4.5e-50 169.5 2.9 4.4 3 2 1 4 4 4 1 Kinesin-associated microtubule-binding Microtub_bd PF16796.5 KFQ91232.1 - 7.3e-23 81.2 2.7 1.1e-22 80.5 0.0 2.8 2 1 0 2 2 2 1 Microtubule binding FAD-SLDH PF12318.8 KFQ91232.1 - 0.095 12.8 0.2 0.095 12.8 0.2 3.4 3 1 0 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase SH3-WW_linker PF16618.5 KFQ91232.1 - 3.7 8.0 11.9 0.16 12.5 3.7 2.6 2 1 0 2 2 2 0 Linker region between SH3 and WW domains on ARHGAP12 Homeodomain PF00046.29 KFQ91233.1 - 0.00015 21.6 7.6 0.00034 20.4 7.6 1.6 1 0 0 1 1 1 1 Homeodomain p450 PF00067.22 KFQ91234.1 - 2.5e-60 204.6 0.0 3.7e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFQ91235.1 - 1.4e-64 218.6 0.0 1.7e-64 218.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 C2 PF00168.30 KFQ91236.1 - 1.8e-99 326.9 5.7 3.5e-18 65.8 0.0 8.5 7 1 1 8 8 8 8 C2 domain FerB PF08150.12 KFQ91236.1 - 1.8e-31 108.5 0.1 4.4e-31 107.3 0.1 1.7 1 0 0 1 1 1 1 FerB (NUC096) domain Ferlin_C PF16165.5 KFQ91236.1 - 1.3e-29 103.1 1.8 1.1e-25 90.3 0.1 2.5 1 1 1 2 2 2 2 Ferlin C-terminus FerA PF08165.11 KFQ91236.1 - 1.4e-22 79.4 0.3 3e-22 78.3 0.3 1.6 1 0 0 1 1 1 1 FerA (NUC095) domain FerI PF08151.12 KFQ91236.1 - 1.9e-18 66.3 0.1 4.9e-18 65.0 0.1 1.8 1 0 0 1 1 1 1 FerI (NUC094) domain PI3K_C2 PF00792.24 KFQ91236.1 - 0.00083 19.3 0.2 0.85 9.5 0.0 2.9 2 0 0 2 2 2 2 Phosphoinositide 3-kinase C2 DUF812 PF05667.11 KFQ91236.1 - 0.058 12.3 1.0 0.089 11.7 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) SIP PF04954.13 KFQ91236.1 - 0.078 13.5 0.1 0.26 11.8 0.1 1.9 2 0 0 2 2 2 0 Siderophore-interacting protein EABR PF12180.8 KFQ91237.1 - 1.2e-17 63.2 1.7 3.3e-17 61.8 1.7 1.8 1 0 0 1 1 1 1 TSG101 and ALIX binding domain of CEP55 CC2-LZ PF16516.5 KFQ91237.1 - 0.00033 21.0 17.4 0.00033 21.0 17.4 4.6 1 1 4 5 5 5 3 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator ADIP PF11559.8 KFQ91237.1 - 0.0054 16.8 20.8 0.0054 16.8 20.8 4.6 2 2 2 4 4 4 2 Afadin- and alpha -actinin-Binding PI_PP_I PF18363.1 KFQ91237.1 - 1.3 9.3 6.2 1.9 8.7 0.7 3.1 1 1 0 2 2 2 0 Phosphoinositide phosphatase insertion domain Fez1 PF06818.15 KFQ91237.1 - 4.1 7.8 67.1 4.2 7.8 27.9 3.4 1 1 3 4 4 4 0 Fez1 7tm_1 PF00001.21 KFQ91238.1 - 4.8e-32 111.3 22.7 5.6e-32 111.1 22.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2208 PF09973.9 KFQ91238.1 - 0.0039 16.8 2.7 0.0088 15.7 2.7 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2208) Lipocalin PF00061.23 KFQ91239.1 - 4.9e-23 81.9 0.0 7.1e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.12 KFQ91239.1 - 2.7e-07 30.6 0.3 4.4e-07 29.9 0.3 1.3 1 1 0 1 1 1 1 Lipocalin-like domain Triabin PF03973.13 KFQ91239.1 - 1.2e-05 25.3 0.6 4.3e-05 23.4 0.6 1.8 1 1 0 1 1 1 1 Triabin PDEase_I PF00233.19 KFQ91240.1 - 3.4e-81 272.5 3.1 3.4e-81 272.5 3.1 2.4 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 KFQ91240.1 - 6.5e-26 91.5 0.0 2.5e-13 50.8 0.0 2.3 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 KFQ91240.1 - 1.1e-11 45.2 0.0 8.7e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 KFQ91240.1 - 4.4e-07 30.3 0.0 0.0067 16.8 0.0 2.5 2 0 0 2 2 2 2 GAF domain SpoVT_C PF15714.5 KFQ91240.1 - 0.002 18.2 0.4 0.44 10.6 0.0 3.2 3 0 0 3 3 3 1 Stage V sporulation protein T C-terminal, transcription factor CAMSAP_CC1 PF17095.5 KFQ91240.1 - 2.6 8.0 8.9 8.3 6.3 8.9 1.8 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin Fra10Ac1 PF09725.9 KFQ91241.1 - 2.5e-53 179.4 5.0 5.6e-53 178.3 5.0 1.6 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 DUF755 PF05501.11 KFQ91241.1 - 0.0012 19.1 9.2 0.0025 18.1 9.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF755) SpoIIIAH PF12685.7 KFQ91241.1 - 0.27 11.1 4.0 0.48 10.2 4.0 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein PriA_CRR PF18319.1 KFQ91241.1 - 0.43 10.6 2.9 0.23 11.5 0.5 1.9 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain Zn_ribbon_recom PF13408.6 KFQ91241.1 - 1.1 9.8 4.6 0.49 11.0 0.6 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain EPTP PF03736.17 KFQ91242.1 - 1.4e-72 239.4 21.5 7.1e-13 48.3 0.1 7.2 7 0 0 7 7 7 7 EPTP domain LRR_8 PF13855.6 KFQ91242.1 - 1.5e-21 75.9 10.9 2.4e-14 52.8 4.9 2.8 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KFQ91242.1 - 5.2e-09 36.3 7.9 6.5e-05 23.2 2.9 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFQ91242.1 - 5.7e-08 32.8 0.9 5.7e-08 32.8 0.9 2.3 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFQ91242.1 - 0.0028 17.2 0.3 0.0087 15.6 0.3 1.6 1 1 1 2 2 2 1 Leucine-rich repeat LRRCT PF01463.24 KFQ91242.1 - 0.058 14.0 0.0 0.24 12.0 0.0 2.1 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain LRR_1 PF00560.33 KFQ91242.1 - 0.95 10.3 10.3 2.8 8.8 0.8 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat EamA PF00892.20 KFQ91243.1 - 0.0013 18.9 0.5 0.0013 18.9 0.5 1.0 1 0 0 1 1 1 1 EamA-like transporter family Phage_holin_4_2 PF04020.13 KFQ91243.1 - 0.049 14.3 0.3 0.054 14.2 0.3 1.1 1 0 0 1 1 1 0 Mycobacterial 4 TMS phage holin, superfamily IV PI-PLC-Y PF00387.19 KFQ91245.1 - 3e-34 117.8 0.0 7.3e-34 116.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain RA PF00788.23 KFQ91245.1 - 1.2e-23 83.5 0.0 6.2e-19 68.4 0.1 2.5 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain C2 PF00168.30 KFQ91245.1 - 4.9e-09 36.4 0.0 9.4e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain CBF PF03914.17 KFQ91246.1 - 5.5e-31 107.9 0.3 3.2e-30 105.4 0.3 2.4 1 0 0 1 1 1 1 CBF/Mak21 family NOC3p PF07540.11 KFQ91246.1 - 4.8e-30 103.9 1.7 4.8e-30 103.9 1.7 3.0 3 0 0 3 3 3 1 Nucleolar complex-associated protein RICTOR_N PF14664.6 KFQ91246.1 - 0.31 10.0 9.2 0.99 8.3 0.7 3.2 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term DBD_HTH PF18430.1 KFQ91246.1 - 0.67 9.8 5.1 1.1 9.1 1.3 2.7 2 0 0 2 2 2 0 Putative DNA-binding domain RabGAP-TBC PF00566.18 KFQ91247.1 - 1.6e-49 168.5 0.0 3.2e-49 167.5 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain 7tm_1 PF00001.21 KFQ91248.1 - 5.4e-76 255.4 12.1 7.3e-76 255.0 12.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ91248.1 - 6.5e-10 38.8 6.8 2.6e-09 36.8 6.8 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFQ91248.1 - 7.9e-07 29.0 15.2 2.1e-06 27.6 9.0 2.5 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFQ91248.1 - 0.0011 18.7 4.4 0.0033 17.2 4.4 1.7 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srw PF10324.9 KFQ91248.1 - 4.4 6.5 9.9 14 4.9 8.9 2.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw DUF621 PF04789.15 KFQ91248.1 - 6.2 5.9 8.9 16 4.6 8.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF621) Ank_5 PF13857.6 KFQ91249.1 - 3.4e-102 333.1 34.7 1.1e-13 51.1 0.2 13.9 5 5 8 13 13 13 13 Ankyrin repeats (many copies) Ank PF00023.30 KFQ91249.1 - 6.6e-101 326.7 45.5 9.2e-08 32.2 0.2 18.0 18 0 0 18 18 18 15 Ankyrin repeat Ank_4 PF13637.6 KFQ91249.1 - 1.4e-98 322.1 22.0 6.5e-13 48.9 0.2 13.6 6 5 7 14 14 14 14 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFQ91249.1 - 5.1e-98 321.8 31.1 6.9e-15 55.4 0.1 9.8 5 5 4 9 9 9 9 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFQ91249.1 - 9.2e-87 274.5 24.9 1.6e-06 28.0 0.1 18.0 19 0 0 19 19 19 14 Ankyrin repeat PARP PF00644.20 KFQ91249.1 - 1e-25 90.5 4.1 3.1e-23 82.4 4.1 2.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SAM_2 PF07647.17 KFQ91249.1 - 1.2e-13 50.9 0.1 3e-13 49.6 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFQ91249.1 - 3e-11 43.6 0.1 7e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Vps39_1 PF10366.9 KFQ91249.1 - 0.0025 18.1 0.8 4.3 7.7 0.0 3.4 4 0 0 4 4 4 2 Vacuolar sorting protein 39 domain 1 CBM_21 PF03370.13 KFQ91250.1 - 7.7e-33 113.0 1.6 1.1e-32 112.5 1.6 1.2 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KFQ91250.1 - 6.8e-17 61.8 1.4 1.5e-16 60.7 1.4 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) HECT PF00632.25 KFQ91251.1 - 3.2e-84 283.0 0.1 5e-84 282.4 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) TipE PF16972.5 KFQ91251.1 - 0.0087 15.3 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Na+ channel auxiliary subunit TipE RAWUL PF16207.5 KFQ91252.1 - 4.9e-13 49.5 1.3 6.7e-12 45.9 0.0 2.9 3 0 0 3 3 3 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 KFQ91252.1 - 6.8e-10 38.6 10.8 6.8e-10 38.6 10.8 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ91252.1 - 6e-08 32.4 11.5 6e-08 32.4 11.5 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFQ91252.1 - 0.0001 22.2 11.3 0.0001 22.2 11.3 2.9 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFQ91252.1 - 0.00011 22.3 10.4 0.00011 22.3 10.4 3.1 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFQ91252.1 - 0.00014 22.1 9.6 0.00014 22.1 9.6 2.7 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 KFQ91252.1 - 0.00048 20.0 11.2 0.00048 20.0 11.2 3.4 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFQ91252.1 - 0.0011 18.8 9.1 0.0011 18.8 9.1 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KFQ91252.1 - 0.0035 17.1 7.1 0.0065 16.3 7.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 KFQ91252.1 - 0.004 17.3 5.3 0.004 17.3 5.3 2.7 3 0 0 3 3 3 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KFQ91252.1 - 0.015 15.6 8.4 0.076 13.3 8.4 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFQ91252.1 - 0.02 14.7 8.4 0.02 14.7 8.4 2.9 3 1 0 3 3 2 0 Prokaryotic RING finger family 4 DUF678 PF05077.12 KFQ91252.1 - 0.18 11.9 3.4 1.6 9.0 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF678) zf-C3HC4_5 PF17121.5 KFQ91252.1 - 0.42 10.5 7.3 1.5 8.8 7.3 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KFQ91252.1 - 3.4 7.6 13.2 0.046 13.6 4.1 2.5 3 0 0 3 3 3 0 zf-RING of BARD1-type protein Zn_Tnp_IS1595 PF12760.7 KFQ91252.1 - 8.4 6.5 12.5 3.4 7.7 0.2 3.0 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Ank_2 PF12796.7 KFQ91253.1 - 8.2e-31 106.4 1.3 2.5e-12 47.2 0.1 3.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFQ91253.1 - 2.6e-30 104.1 4.5 5.3e-10 39.4 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFQ91253.1 - 9.2e-28 96.3 0.2 3.3e-09 37.1 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KFQ91253.1 - 2.9e-26 90.7 0.2 3.5e-06 27.2 0.0 4.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KFQ91253.1 - 2.4e-25 85.8 0.1 8.8e-06 25.7 0.0 5.5 6 0 0 6 6 6 4 Ankyrin repeat HlyU PF10115.9 KFQ91253.1 - 0.024 14.7 0.2 0.05 13.7 0.2 1.4 1 0 0 1 1 1 0 Transcriptional activator HlyU CDRT4 PF15213.6 KFQ91253.1 - 0.024 15.3 1.0 0.049 14.2 1.0 1.4 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein RNase_P_p30 PF01876.16 KFQ91254.1 - 5.4e-62 209.1 0.0 6.3e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 7tm_1 PF00001.21 KFQ91255.1 - 1.1e-70 238.0 14.1 1.4e-70 237.6 14.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ91255.1 - 0.00025 20.5 13.5 0.00047 19.6 13.5 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFQ91255.1 - 0.00026 20.8 5.8 0.00026 20.8 5.8 1.8 2 1 0 3 3 3 1 Olfactory receptor Kinesin PF00225.23 KFQ91256.1 - 4.1e-97 325.1 1.4 4.1e-97 325.1 1.4 4.0 3 1 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 KFQ91256.1 - 5.5e-17 62.1 0.1 5.5e-17 62.1 0.1 5.2 4 1 0 4 4 4 2 Microtubule binding BRE1 PF08647.11 KFQ91256.1 - 0.0084 16.2 8.5 0.0084 16.2 8.5 12.6 4 2 10 14 14 14 2 BRE1 E3 ubiquitin ligase Fumble PF03630.14 KFQ91257.1 - 6e-121 403.6 0.1 6.9e-121 403.4 0.1 1.0 1 0 0 1 1 1 1 Fumble SpoU_methylase PF00588.19 KFQ91257.1 - 0.072 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 SpoU rRNA Methylase family MFS_1 PF07690.16 KFQ91258.1 - 1.5e-34 119.5 34.7 1.4e-20 73.5 9.5 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFQ91258.1 - 0.0026 16.7 5.4 0.0026 16.7 5.4 3.0 2 1 0 2 2 2 1 MFS_1 like family Gate PF07670.14 KFQ91258.1 - 4.4 7.6 10.1 2.2 8.6 2.7 3.1 2 2 0 2 2 2 0 Nucleoside recognition TPR_2 PF07719.17 KFQ91259.1 - 2.3e-22 77.2 34.5 0.00021 21.1 0.4 10.6 10 1 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ91259.1 - 2.5e-22 77.6 4.1 0.001 19.7 0.0 8.6 6 1 3 9 9 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ91259.1 - 4e-20 70.7 32.6 2e-06 27.3 0.1 9.9 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ91259.1 - 5.6e-18 63.6 30.0 6.6e-05 22.8 0.0 9.7 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ91259.1 - 2.2e-16 60.1 7.8 0.017 15.6 0.0 6.5 5 2 1 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ91259.1 - 1.3e-15 56.8 27.2 5.6e-06 25.9 0.6 8.4 7 1 1 8 8 8 2 TPR repeat TPR_12 PF13424.6 KFQ91259.1 - 1.5e-14 54.0 19.9 0.00012 22.3 0.5 6.7 4 3 3 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ91259.1 - 4e-13 48.7 22.7 0.65 10.5 0.0 9.0 11 0 0 11 11 8 6 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ91259.1 - 3.1e-12 45.6 5.9 0.022 14.8 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_15 PF13429.6 KFQ91259.1 - 1.8e-11 43.8 6.5 7.9e-05 22.0 0.1 4.3 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ91259.1 - 6.6e-11 42.7 8.4 0.051 14.2 0.1 6.0 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ91259.1 - 8.6e-11 41.4 12.4 0.0083 16.0 0.4 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ91259.1 - 2e-07 31.1 14.9 0.41 10.9 0.5 6.0 4 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KFQ91259.1 - 3.6e-07 30.2 0.1 0.59 10.3 0.0 5.7 4 1 2 6 6 6 1 Tetratricopeptide repeat NARP1 PF12569.8 KFQ91259.1 - 2.7e-05 23.3 0.0 2.7e-05 23.3 0.0 3.8 2 2 1 4 4 4 1 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 KFQ91259.1 - 4.6e-05 23.8 16.3 7.5 7.4 0.0 7.7 9 0 0 9 9 6 0 Tetratricopeptide repeat RPN7 PF10602.9 KFQ91259.1 - 5.4e-05 23.0 8.3 0.0026 17.5 0.4 4.3 4 0 0 4 4 4 1 26S proteasome subunit RPN7 SPOB_a PF14689.6 KFQ91259.1 - 0.0011 18.6 2.9 0.44 10.3 0.0 3.6 4 0 0 4 4 4 1 Sensor_kinase_SpoOB-type, alpha-helical domain PPR PF01535.20 KFQ91259.1 - 0.0017 18.5 2.4 5.9 7.4 0.0 4.5 4 0 0 4 4 4 1 PPR repeat DUF627 PF04781.12 KFQ91259.1 - 0.012 15.6 0.7 2.8 8.0 0.0 3.7 4 0 0 4 4 3 0 Protein of unknown function (DUF627) TPR_MalT PF17874.1 KFQ91259.1 - 0.012 15.0 1.4 11 5.3 0.2 4.1 3 1 0 4 4 4 0 MalT-like TPR region Spore_III_AB PF09548.10 KFQ91259.1 - 0.043 13.9 3.1 0.05 13.7 0.5 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) TPR_4 PF07721.14 KFQ91259.1 - 0.062 14.0 0.1 4.6 8.1 0.0 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat IF-2B PF01008.17 KFQ91259.1 - 0.11 11.7 0.1 0.2 10.8 0.1 1.3 1 0 0 1 1 1 0 Initiation factor 2 subunit family TPR_3 PF07720.12 KFQ91259.1 - 0.69 10.0 6.5 11 6.2 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 KFQ91259.1 - 2.4 8.5 7.3 11 6.5 0.0 4.9 6 2 2 8 8 6 0 Tetratricopeptide repeat Sel1 PF08238.12 KFQ91259.1 - 3.7 8.4 10.5 6.5 7.6 0.0 4.7 6 0 0 6 6 3 0 Sel1 repeat TOM20_plant PF06552.12 KFQ91259.1 - 7.6 6.2 8.2 32 4.2 0.0 4.5 3 2 2 6 6 6 0 Plant specific mitochondrial import receptor subunit TOM20 Abhydrolase_1 PF00561.20 KFQ91260.1 - 9.3e-28 97.6 0.5 1.2e-27 97.2 0.5 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KFQ91260.1 - 3.2e-25 87.5 0.0 9.4e-25 86.0 0.0 1.8 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KFQ91260.1 - 2.1e-08 33.7 0.0 1.3e-05 24.6 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 KFQ91260.1 - 0.0014 18.4 0.1 0.016 14.9 0.1 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KFQ91260.1 - 0.0028 18.3 0.0 0.0081 16.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 KFQ91260.1 - 0.029 14.2 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.8 KFQ91260.1 - 0.072 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) FA_hydroxylase PF04116.13 KFQ91261.1 - 2.1e-24 86.4 19.1 2.1e-24 86.4 19.1 1.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Actin PF00022.19 KFQ91262.1 - 7.6e-150 499.0 0.0 2.5e-149 497.3 0.0 1.7 1 1 0 1 1 1 1 Actin USP8_dimer PF08969.11 KFQ91263.1 - 2.2e-18 66.5 0.1 2.2e-18 66.5 0.1 2.2 2 1 0 3 3 3 1 USP8 dimerisation domain JAB PF01398.21 KFQ91263.1 - 6.4e-17 61.6 0.3 1.8e-16 60.2 0.0 1.9 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KFQ91263.1 - 1.2e-06 28.3 0.0 2.6e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain TPR_8 PF13181.6 KFQ91263.1 - 0.065 13.5 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Antibiotic_NAT PF02522.14 KFQ91263.1 - 0.22 11.3 0.5 0.36 10.6 0.5 1.3 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase ABC_tran_Xtn PF12848.7 KFQ91263.1 - 2 8.5 15.1 1.6 8.8 13.6 1.6 2 0 0 2 2 2 0 ABC transporter GrpB PF04229.14 KFQ91263.1 - 4.5 7.4 7.8 11 6.2 1.2 3.0 2 1 0 3 3 3 0 GrpB protein Abhydrolase_1 PF00561.20 KFQ91264.1 - 3e-23 82.8 0.0 6.8e-23 81.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFQ91264.1 - 2.1e-05 23.9 0.0 0.024 13.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydro_lipase PF04083.16 KFQ91264.1 - 0.0041 16.7 0.0 0.0087 15.6 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Ank_2 PF12796.7 KFQ91265.1 - 2.2e-25 89.0 0.7 1.4e-12 48.0 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ91265.1 - 7.9e-24 83.7 5.1 9.8e-07 29.2 0.1 4.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFQ91265.1 - 1.6e-23 82.5 1.6 6.8e-11 42.2 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFQ91265.1 - 8.4e-21 73.4 2.3 6.4e-06 26.4 0.0 5.7 5 1 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 KFQ91265.1 - 5.8e-17 60.1 2.9 7.1e-05 22.9 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Abhydrolase_1 PF00561.20 KFQ91266.1 - 1.2e-23 84.1 0.5 1.8e-22 80.2 0.5 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFQ91266.1 - 0.00023 20.5 0.0 0.65 9.2 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydro_lipase PF04083.16 KFQ91266.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KFQ91267.1 - 9.6e-24 84.4 0.1 1e-14 54.8 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KFQ91267.1 - 6e-21 73.8 0.1 1.4e-20 72.6 0.0 1.7 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KFQ91267.1 - 6e-05 22.4 0.0 0.057 12.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 TMEM72 PF16054.5 KFQ91268.1 - 1.3e-67 227.0 0.2 1.9e-67 226.5 0.2 1.2 1 0 0 1 1 1 1 Transmembrane protein family 72 IL8 PF00048.20 KFQ91269.1 - 1.5e-08 34.7 1.9 1.9e-08 34.3 1.9 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like SNF2_N PF00176.23 KFQ91270.1 - 1e-72 244.8 0.5 2.8e-72 243.3 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFQ91270.1 - 1.3e-17 64.1 0.0 7.2e-17 61.7 0.0 2.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TFIIF_beta PF02270.15 KFQ91270.1 - 0.0064 16.6 0.0 0.021 14.9 0.0 2.0 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TGF_beta PF00019.20 KFQ91271.1 - 3.4e-33 114.7 0.2 7.9e-33 113.5 0.1 1.7 2 0 0 2 2 2 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFQ91271.1 - 6.9e-22 78.4 0.9 1e-21 77.8 0.9 1.2 1 0 0 1 1 1 1 TGF-beta propeptide DUF3330 PF11809.8 KFQ91271.1 - 0.13 12.4 0.4 3.4 7.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3330) Homeodomain PF00046.29 KFQ91272.1 - 3e-22 78.2 0.6 5.5e-22 77.4 0.6 1.4 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 KFQ91272.1 - 2e-07 30.6 1.5 2e-07 30.6 1.5 2.4 2 0 0 2 2 2 1 OAR domain Homeobox_KN PF05920.11 KFQ91272.1 - 0.0033 17.3 0.5 0.015 15.2 0.1 2.1 2 0 0 2 2 2 1 Homeobox KN domain EspF PF04806.12 KFQ91272.1 - 0.23 11.9 0.1 0.23 11.9 0.1 3.0 3 0 0 3 3 3 0 EspF protein repeat TP2 PF01254.18 KFQ91272.1 - 8.5 7.0 8.2 5.2 7.7 0.7 2.4 2 0 0 2 2 2 0 Nuclear transition protein 2 V-set PF07686.17 KFQ91274.1 - 1.6e-08 34.7 1.1 2.4e-08 34.1 0.1 1.8 2 1 0 2 2 2 1 Immunoglobulin V-set domain ig PF00047.25 KFQ91274.1 - 3.7e-06 27.0 0.6 1.6e-05 25.0 0.1 2.2 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFQ91274.1 - 2.9e-05 24.0 0.0 7.3e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFQ91274.1 - 6.9e-05 23.1 0.1 0.004 17.5 0.1 2.6 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFQ91274.1 - 9.3e-05 23.0 0.0 0.00051 20.6 0.0 2.2 1 1 0 1 1 1 1 Immunoglobulin domain Beach PF02138.18 KFQ91275.1 - 1.3e-117 392.1 0.4 2.5e-117 391.2 0.2 1.5 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 KFQ91275.1 - 5.5e-12 45.7 0.1 1.4e-11 44.4 0.1 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 KFQ91275.1 - 8.6e-08 32.7 15.7 3.2e-05 24.6 0.1 5.7 4 1 1 5 5 5 3 WD domain, G-beta repeat LRR_8 PF13855.6 KFQ91276.1 - 5.2e-17 61.4 16.7 2.3e-07 30.5 0.3 4.7 3 1 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 KFQ91276.1 - 1.1e-12 48.0 29.0 9.5e-06 25.9 0.3 5.0 2 1 5 7 7 7 6 Leucine Rich repeats (2 copies) LEDGF PF11467.8 KFQ91276.1 - 0.00015 21.4 0.3 0.025 14.2 0.1 2.5 2 1 0 2 2 2 2 Lens epithelium-derived growth factor (LEDGF) LRR_1 PF00560.33 KFQ91276.1 - 0.0002 21.4 16.2 8.4 7.4 1.6 6.6 6 1 0 6 6 6 3 Leucine Rich Repeat RIX1 PF08167.12 KFQ91277.1 - 0.0059 16.4 0.1 0.075 12.8 0.0 2.5 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis DUF1146 PF06612.11 KFQ91277.1 - 3.4 7.8 5.8 1.5 8.9 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1146) RhoGAP PF00620.27 KFQ91278.1 - 3.2e-48 163.4 0.0 8.2e-48 162.1 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KFQ91278.1 - 5.5e-22 78.3 0.1 1.7e-21 76.7 0.0 1.9 2 0 0 2 2 1 1 PH domain PH_11 PF15413.6 KFQ91278.1 - 4.2e-06 27.1 6.5 4e-05 24.0 0.6 3.0 3 1 0 3 3 3 1 Pleckstrin homology domain PH_8 PF15409.6 KFQ91278.1 - 0.00052 20.3 0.2 0.052 13.8 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain ATG16 PF08614.11 KFQ91278.1 - 0.0006 20.1 12.9 0.0013 19.0 12.9 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF812 PF05667.11 KFQ91278.1 - 0.001 18.1 5.6 0.0015 17.5 5.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) FPP PF05911.11 KFQ91278.1 - 0.0012 17.2 8.3 0.0016 16.7 8.3 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil PspA_IM30 PF04012.12 KFQ91278.1 - 0.0015 18.1 5.3 0.0027 17.3 5.3 1.5 1 0 0 1 1 1 1 PspA/IM30 family PH_3 PF14593.6 KFQ91278.1 - 0.015 15.4 0.0 0.071 13.2 0.0 2.0 2 0 0 2 2 2 0 PH domain RIH_assoc PF08454.11 KFQ91278.1 - 0.037 13.9 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 RyR and IP3R Homology associated THOC7 PF05615.13 KFQ91278.1 - 0.18 12.1 10.1 1.9 8.8 9.4 2.4 1 1 0 1 1 1 0 Tho complex subunit 7 PH_9 PF15410.6 KFQ91278.1 - 0.35 11.2 3.2 14 6.1 0.1 2.8 3 0 0 3 3 2 0 Pleckstrin homology domain CENP-Q PF13094.6 KFQ91278.1 - 0.42 10.8 11.9 1 9.6 11.9 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit CENP-H PF05837.12 KFQ91278.1 - 0.5 10.8 7.3 1.6 9.1 7.3 2.0 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SLX9 PF15341.6 KFQ91278.1 - 0.53 10.7 5.5 1.2 9.5 5.5 1.6 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 SlyX PF04102.12 KFQ91278.1 - 0.57 10.8 5.2 2.3 8.9 5.2 2.1 1 0 0 1 1 1 0 SlyX Fib_alpha PF08702.10 KFQ91278.1 - 1.4 9.1 6.5 3.5 7.8 3.9 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ADIP PF11559.8 KFQ91278.1 - 1.4 9.0 14.3 2.1 8.4 13.3 1.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.12 KFQ91278.1 - 1.5 8.9 17.3 2.9 8.0 16.9 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Cep57_MT_bd PF06657.13 KFQ91278.1 - 4 8.0 14.5 0.1 13.0 3.1 2.7 1 1 1 2 2 1 0 Centrosome microtubule-binding domain of Cep57 TMF_DNA_bd PF12329.8 KFQ91278.1 - 4 7.5 13.3 0.73 9.9 8.7 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Striatin PF08232.12 KFQ91278.1 - 4.6 7.8 11.5 2.5 8.7 8.8 2.0 1 1 1 2 2 2 0 Striatin family Tropomyosin_1 PF12718.7 KFQ91278.1 - 6.3 6.9 17.3 23 5.1 17.2 1.9 1 1 1 2 2 2 0 Tropomyosin like Spc24 PF08286.11 KFQ91278.1 - 7.1 6.9 9.7 1.5 9.1 5.9 1.9 2 0 0 2 2 1 0 Spc24 subunit of Ndc80 Pkinase PF00069.25 KFQ91279.1 - 2e-63 214.2 0.0 2.5e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ91279.1 - 2.5e-29 102.4 0.0 3.3e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFQ91279.1 - 2.6e-07 30.2 0.2 4e-07 29.6 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFQ91279.1 - 2.6e-05 23.7 0.1 4.8e-05 22.8 0.1 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFQ91279.1 - 0.00045 19.9 0.2 0.00088 18.9 0.2 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KFQ91279.1 - 0.0007 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF530 PF04409.12 KFQ91279.1 - 0.046 12.1 0.0 0.091 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF530) FTA2 PF13095.6 KFQ91279.1 - 0.048 13.3 0.1 0.1 12.2 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 PDZ_6 PF17820.1 KFQ91280.1 - 1.1e-12 47.6 0.1 1.6e-12 47.0 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFQ91280.1 - 7.2e-10 39.1 0.0 1.1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFQ91280.1 - 0.00016 21.9 0.0 0.00025 21.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 KFQ91280.1 - 0.075 13.0 0.0 0.17 11.9 0.0 1.6 1 1 0 1 1 1 0 Tricorn protease PDZ domain PDZ_4 PF17816.1 KFQ91280.1 - 0.086 13.2 0.0 1.9 8.9 0.0 2.4 2 0 0 2 2 2 0 PDZ domain Y_phosphatase PF00102.27 KFQ91281.1 - 1.1e-75 254.3 0.2 1.2e-75 254.1 0.2 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFQ91281.1 - 0.00013 21.8 0.1 0.00021 21.1 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFQ91281.1 - 0.0049 17.0 0.0 0.011 15.8 0.0 1.6 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KFQ91281.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family TGF_beta PF00019.20 KFQ91282.1 - 2.7e-30 105.4 0.4 7.2e-30 104.0 0.4 1.7 1 0 0 1 1 1 1 Transforming growth factor beta like domain Stb3 PF10330.9 KFQ91282.1 - 0.16 12.0 0.2 2.4 8.2 0.1 2.5 2 0 0 2 2 2 0 Putative Sin3 binding protein FDF PF09532.10 KFQ91282.1 - 0.55 11.1 3.8 0.99 10.3 3.8 1.4 1 0 0 1 1 1 0 FDF domain TGF_beta PF00019.20 KFQ91283.1 - 1.1e-28 100.2 0.3 2.6e-28 99.0 0.3 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFQ91283.1 - 1e-17 64.7 4.1 1e-17 64.7 0.8 2.3 2 1 0 2 2 2 1 TGF-beta propeptide Peptidase_S41_N PF11918.8 KFQ91284.1 - 2.4e-119 393.2 7.9 1.7e-37 128.6 0.1 4.6 4 0 0 4 4 4 4 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Peptidase_S41 PF03572.18 KFQ91284.1 - 9.9e-98 324.5 0.0 1.5e-25 89.7 0.0 4.2 4 0 0 4 4 4 4 Peptidase family S41 muHD PF10291.9 KFQ91284.1 - 0.011 15.2 0.0 4.8 6.6 0.0 3.1 3 0 0 3 3 3 0 Muniscin C-terminal mu homology domain zf-C2H2_4 PF13894.6 KFQ91285.1 - 0.00038 21.1 32.0 0.023 15.5 4.8 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KFQ91285.1 - 0.0039 17.6 28.2 0.13 12.8 6.7 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type SET PF00856.28 KFQ91285.1 - 0.013 15.9 1.7 0.051 14.0 0.0 2.5 2 1 0 2 2 2 0 SET domain zf-C2H2_2 PF12756.7 KFQ91285.1 - 0.02 15.2 16.0 1.6 9.1 2.8 3.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KFQ91285.1 - 0.14 12.1 5.0 0.71 9.8 0.6 2.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Zn-C2H2_12 PF18112.1 KFQ91285.1 - 0.28 11.7 4.1 1.1 9.8 4.1 2.0 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_jaz PF12171.8 KFQ91285.1 - 0.53 10.6 19.0 0.37 11.1 1.6 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFQ91285.1 - 1 9.2 6.0 0.31 10.9 2.2 2.1 2 0 0 2 2 2 0 GAGA factor CpXC PF14353.6 KFQ91285.1 - 3.8 7.6 10.4 13 5.9 0.4 3.7 3 1 0 3 3 3 0 CpXC protein zf-H2C2_2 PF13465.6 KFQ91285.1 - 9.1 6.9 23.2 3.6 8.2 7.7 4.0 3 1 0 3 3 3 0 Zinc-finger double domain Anth_Ig PF05587.13 KFQ91286.1 - 4.3e-30 104.0 0.1 1e-29 102.8 0.1 1.6 2 0 0 2 2 2 1 Anthrax receptor extracellular domain VWA PF00092.28 KFQ91286.1 - 2.4e-19 70.2 0.0 3.2e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KFQ91286.1 - 0.00016 21.2 0.0 0.00021 20.8 0.0 1.1 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Ant_C PF05586.11 KFQ91287.1 - 4.1e-45 152.3 1.4 5.2e-45 152.0 1.4 1.1 1 0 0 1 1 1 1 Anthrax receptor C-terminus region Annexin PF00191.20 KFQ91288.1 - 1.7e-98 322.7 14.0 3.3e-27 94.4 0.8 4.1 4 0 0 4 4 4 4 Annexin Sigma70_ner PF04546.13 KFQ91288.1 - 0.00014 21.8 0.6 0.081 12.8 0.0 2.6 2 1 1 3 3 3 2 Sigma-70, non-essential region Myb_DNA-bind_7 PF15963.5 KFQ91288.1 - 0.00018 21.3 0.1 1.3 9.0 0.0 3.4 4 0 0 4 4 4 2 Myb DNA-binding like FeoB_Cyto PF17910.1 KFQ91288.1 - 0.011 16.3 2.6 0.12 12.9 0.4 3.1 3 0 0 3 3 3 0 FeoB cytosolic helical domain MnmE_helical PF12631.7 KFQ91288.1 - 0.46 10.6 3.3 0.71 10.0 3.3 1.5 1 1 0 1 1 1 0 MnmE helical domain 7tm_1 PF00001.21 KFQ91289.1 - 9.5e-49 166.1 26.8 1.1e-48 165.9 26.8 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ91289.1 - 4.3e-06 26.3 26.2 8.4e-06 25.4 26.2 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Git3 PF11710.8 KFQ91289.1 - 5 6.9 19.8 0.42 10.3 13.2 2.3 1 1 1 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 ubiquitin PF00240.23 KFQ91290.1 - 3.8e-07 29.8 0.5 5.6e-07 29.2 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_4 PF18036.1 KFQ91290.1 - 0.0028 17.6 1.3 0.39 10.8 0.2 2.1 1 1 1 2 2 2 2 Ubiquitin-like domain Rad60-SLD PF11976.8 KFQ91290.1 - 0.0089 15.8 0.2 0.013 15.3 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFQ91290.1 - 0.27 11.7 2.4 0.87 10.1 2.4 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain PSP94 PF05825.11 KFQ91291.1 - 2.3e-25 89.0 8.3 2.5e-25 88.9 8.3 1.0 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) Pacifastin_I PF05375.13 KFQ91291.1 - 0.00036 20.2 4.3 0.00036 20.2 4.3 1.9 3 0 0 3 3 3 1 Pacifastin inhibitor (LCMII) TILa PF12714.7 KFQ91291.1 - 0.00069 19.5 7.4 0.0011 18.8 7.4 1.7 1 1 0 1 1 1 1 TILa domain VWC PF00093.18 KFQ91291.1 - 0.0033 17.7 9.7 0.0094 16.2 9.7 1.8 1 1 0 1 1 1 1 von Willebrand factor type C domain Fusion_gly PF00523.18 KFQ91291.1 - 0.13 10.5 3.4 0.13 10.5 3.4 1.0 1 0 0 1 1 1 0 Fusion glycoprotein F0 PSP94 PF05825.11 KFQ91292.1 - 9.8e-20 70.9 6.0 1.1e-19 70.8 6.0 1.0 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) VWC PF00093.18 KFQ91292.1 - 0.0028 17.9 6.4 0.009 16.3 6.4 1.8 1 1 0 1 1 1 1 von Willebrand factor type C domain CAP-ZIP_m PF15255.6 KFQ91293.1 - 6.6e-61 204.6 6.5 6.6e-61 204.6 6.5 3.4 3 0 0 3 3 3 1 WASH complex subunit CAP-Z interacting, central region Chisel PF15355.6 KFQ91293.1 - 0.0097 16.1 4.1 0.24 11.6 0.2 4.1 2 0 0 2 2 2 1 Stretch-responsive small skeletal muscle X protein, Chisel ubiquitin PF00240.23 KFQ91294.1 - 3e-20 71.7 0.0 5.5e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family zf-AN1 PF01428.16 KFQ91294.1 - 1.1e-08 35.1 8.7 2.1e-08 34.2 8.7 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD PF11976.8 KFQ91294.1 - 2.8e-05 23.8 0.0 6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFQ91294.1 - 7.3e-05 23.1 0.0 0.00027 21.3 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain RINGv PF12906.7 KFQ91295.1 - 1.8e-15 56.8 16.6 5.3e-15 55.3 16.6 1.9 1 0 0 1 1 1 1 RING-variant domain DctQ PF04290.12 KFQ91295.1 - 0.013 15.5 1.2 0.018 14.9 1.2 1.2 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component p450 PF00067.22 KFQ91296.1 - 5.9e-151 503.3 0.2 6.7e-151 503.2 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1819 PF08849.11 KFQ91296.1 - 0.021 14.6 0.1 5.2 6.8 0.1 2.3 2 0 0 2 2 2 0 Putative inner membrane protein (DUF1819) BLOC1_2 PF10046.9 KFQ91297.1 - 4e-33 113.6 7.3 5.3e-33 113.2 7.3 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 ParB PF08775.10 KFQ91297.1 - 0.0024 18.4 1.3 0.0035 17.8 1.3 1.3 1 0 0 1 1 1 1 ParB family DUF948 PF06103.11 KFQ91297.1 - 0.045 14.0 0.2 0.1 12.9 0.2 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 KFQ91297.1 - 0.051 14.0 0.3 0.11 13.0 0.1 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Pox_Ag35 PF03286.14 KFQ91297.1 - 0.18 11.6 0.9 0.21 11.4 0.9 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein XhlA PF10779.9 KFQ91297.1 - 0.26 11.5 5.1 15 5.9 0.0 3.2 3 1 0 3 3 3 0 Haemolysin XhlA PKD_channel PF08016.12 KFQ91298.1 - 3.2e-159 530.2 18.6 3.2e-159 530.2 18.6 1.4 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 KFQ91298.1 - 4.9e-28 98.0 27.7 4.9e-28 98.0 27.7 1.6 2 0 0 2 2 2 1 Ion transport protein Fer4_24 PF18109.1 KFQ91298.1 - 7.8e-19 67.7 1.5 1.6e-18 66.6 1.5 1.6 1 0 0 1 1 1 1 Ferredoxin I 4Fe-4S cluster domain EF-hand_8 PF13833.6 KFQ91298.1 - 0.00092 19.0 1.8 0.049 13.5 0.6 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KFQ91298.1 - 0.0065 16.3 2.6 0.67 10.0 0.1 3.8 4 0 0 4 4 4 1 EF-hand domain Spc7_N PF15402.6 KFQ91298.1 - 0.019 13.3 0.4 0.024 12.9 0.4 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 EF-hand_1 PF00036.32 KFQ91298.1 - 0.019 14.5 5.5 0.15 11.7 0.2 3.6 4 0 0 4 4 4 0 EF hand EF-hand_7 PF13499.6 KFQ91298.1 - 0.12 12.9 1.2 1.3 9.5 0.4 2.8 2 0 0 2 2 2 0 EF-hand domain pair DUF2205 PF10224.9 KFQ91298.1 - 1.1 9.3 4.6 2.5 8.1 0.9 2.7 2 0 0 2 2 2 0 Short coiled-coil protein FA_desaturase PF00487.24 KFQ91299.1 - 1.7e-15 57.6 8.1 2.9e-15 56.8 8.1 1.3 1 0 0 1 1 1 1 Fatty acid desaturase wnt PF00110.19 KFQ91300.1 - 5.7e-95 318.5 18.7 7.1e-95 318.1 18.7 1.0 1 0 0 1 1 1 1 wnt family WD40 PF00400.32 KFQ91301.1 - 1.8e-05 25.4 5.0 0.1 13.5 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Sec16_C PF12931.7 KFQ91301.1 - 4.3e-05 23.3 0.7 0.00053 19.7 0.7 2.4 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Prp18 PF02840.15 KFQ91301.1 - 0.073 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Prp18 domain NDUF_B8 PF05821.11 KFQ91302.1 - 2e-74 249.3 9.0 2.2e-74 249.2 9.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Cupin_8 PF13621.6 KFQ91303.1 - 1.8e-40 139.3 0.3 2.2e-40 139.0 0.3 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KFQ91303.1 - 1.9e-07 30.9 0.4 2.7e-07 30.4 0.1 1.4 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.22 KFQ91303.1 - 0.029 14.8 0.2 0.14 12.6 0.2 2.1 1 1 0 1 1 1 0 JmjC domain, hydroxylase Cupin_2 PF07883.11 KFQ91303.1 - 0.05 13.3 0.0 0.57 9.9 0.0 2.2 2 0 0 2 2 2 0 Cupin domain Myosin_head PF00063.21 KFQ91306.1 - 1.4e-266 886.1 8.1 1.4e-266 886.1 8.1 3.7 4 1 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KFQ91306.1 - 7.5e-76 255.9 145.5 6.7e-40 136.8 62.1 2.1 1 1 1 2 2 2 2 Myosin tail Myosin_N PF02736.19 KFQ91306.1 - 1.3e-12 47.4 3.9 3.2e-12 46.1 3.9 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain DUF1664 PF07889.12 KFQ91306.1 - 0.00068 19.7 77.4 0.058 13.4 1.6 8.0 2 1 5 8 8 8 4 Protein of unknown function (DUF1664) IQ PF00612.27 KFQ91306.1 - 0.0025 17.5 0.9 0.022 14.5 0.1 2.5 2 0 0 2 2 2 1 IQ calmodulin-binding motif Filament PF00038.21 KFQ91306.1 - 0.27 10.8 119.3 0.053 13.1 13.5 5.9 1 1 5 6 6 6 0 Intermediate filament protein ADIP PF11559.8 KFQ91306.1 - 1.1 9.3 121.3 0.12 12.5 19.0 7.4 1 1 5 7 7 7 0 Afadin- and alpha -actinin-Binding zf-C2H2 PF00096.26 KFQ91309.1 - 2.3e-17 62.4 16.3 3.6e-06 27.1 4.9 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ91309.1 - 1.5e-12 47.3 16.3 3.9e-07 30.2 4.0 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ91309.1 - 1.2e-11 44.3 15.0 0.0005 20.7 0.3 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ91309.1 - 4.3e-09 36.4 1.5 0.0066 16.7 0.0 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding DUF2256 PF10013.9 KFQ91309.1 - 3.4e-06 27.1 1.5 1.1 9.4 0.0 3.2 3 0 0 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2256) zf-met PF12874.7 KFQ91309.1 - 5.2e-05 23.5 5.8 0.2 12.1 0.1 3.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFQ91309.1 - 0.0002 21.3 19.0 0.047 13.7 0.3 3.7 3 1 0 3 3 3 2 C2H2-type zinc finger zf_UBZ PF18439.1 KFQ91309.1 - 0.00038 20.0 4.7 0.57 9.8 0.8 3.1 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger zinc_ribbon_9 PF14369.6 KFQ91309.1 - 0.0064 16.7 4.0 0.93 9.8 0.0 2.8 3 0 0 3 3 3 2 zinc-ribbon zf-C2H2_8 PF15909.5 KFQ91309.1 - 0.011 16.0 3.1 0.015 15.5 0.2 1.9 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-Di19 PF05605.12 KFQ91309.1 - 0.011 16.0 6.9 0.53 10.6 2.7 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.16 KFQ91309.1 - 0.012 15.7 4.3 2 8.6 0.1 2.8 3 0 0 3 3 3 0 AN1-like Zinc finger DZR PF12773.7 KFQ91309.1 - 0.018 15.1 3.0 0.055 13.5 3.0 1.8 1 1 0 1 1 1 0 Double zinc ribbon DNA_RNApol_7kD PF03604.13 KFQ91309.1 - 0.029 14.0 0.6 6.1 6.6 0.1 2.9 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_11 PF16622.5 KFQ91309.1 - 0.032 14.0 5.4 1 9.2 0.2 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type CpXC PF14353.6 KFQ91309.1 - 0.037 14.1 3.9 0.75 9.9 0.5 2.8 1 1 2 3 3 3 0 CpXC protein Zn-ribbon_8 PF09723.10 KFQ91309.1 - 0.038 14.1 5.7 0.078 13.1 2.8 2.4 1 1 1 2 2 2 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 KFQ91309.1 - 0.047 14.5 0.2 0.079 13.7 0.1 1.4 1 1 0 1 1 1 0 zinc-ribbon family FYDLN_acid PF09538.10 KFQ91309.1 - 0.048 14.3 0.9 3 8.6 0.5 2.7 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) HypA PF01155.19 KFQ91309.1 - 0.055 13.5 0.2 0.069 13.2 0.2 1.3 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ADK_lid PF05191.14 KFQ91309.1 - 0.064 13.3 4.4 9.3 6.3 0.0 3.2 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-C2H2_2 PF12756.7 KFQ91309.1 - 0.08 13.3 3.7 2.6 8.4 3.7 2.3 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 KFQ91309.1 - 0.089 13.3 7.4 0.23 12.0 0.2 2.3 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zinc-ribbons_6 PF07191.12 KFQ91309.1 - 0.099 12.6 1.7 0.86 9.6 1.7 2.1 1 1 0 1 1 1 0 zinc-ribbons XPA_N PF01286.18 KFQ91309.1 - 0.1 12.7 3.6 5.4 7.2 0.1 3.0 3 0 0 3 3 3 0 XPA protein N-terminal PknG_rubred PF16919.5 KFQ91309.1 - 0.12 12.5 2.7 0.36 11.0 1.7 2.0 1 1 1 2 2 2 0 Protein kinase G rubredoxin domain zf-LYAR PF08790.11 KFQ91309.1 - 0.15 12.0 3.9 22 5.1 0.3 3.1 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-BED PF02892.15 KFQ91309.1 - 0.16 12.1 12.4 0.25 11.4 0.8 2.9 2 1 1 3 3 3 0 BED zinc finger zinc_ribbon_4 PF13717.6 KFQ91309.1 - 0.38 10.7 5.3 4.7 7.2 0.3 2.8 2 1 0 2 2 2 0 zinc-ribbon domain YacG PF03884.14 KFQ91309.1 - 0.39 10.5 6.7 4 7.3 0.2 2.7 2 1 0 2 2 2 0 DNA gyrase inhibitor YacG HNH PF01844.23 KFQ91309.1 - 0.78 10.0 5.6 10 6.4 0.2 3.0 3 0 0 3 3 3 0 HNH endonuclease DUF4824 PF16106.5 KFQ91310.1 - 0.025 13.9 3.2 0.04 13.2 1.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4824) Ribosomal_L22 PF00237.19 KFQ91311.1 - 4.1e-49 165.1 0.1 6.2e-49 164.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Kazal_2 PF07648.15 KFQ91313.1 - 7e-19 67.7 33.6 1.2e-10 41.3 7.8 4.6 4 0 0 4 4 4 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFQ91313.1 - 2.3e-13 49.9 19.7 4.5e-09 36.2 5.8 4.7 3 2 2 5 5 5 2 Kazal-type serine protease inhibitor domain EGF_2 PF07974.13 KFQ91313.1 - 0.0012 19.2 9.0 0.0012 19.2 9.0 5.2 3 2 2 5 5 5 2 EGF-like domain EphA2_TM PF14575.6 KFQ91313.1 - 0.52 11.2 2.0 0.61 11.0 0.3 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4834 PF16118.5 KFQ91313.1 - 1.3 10.0 2.9 2.4 9.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Myosin_head PF00063.21 KFQ91315.1 - 2.3e-267 888.7 5.3 2.9e-267 888.3 5.3 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KFQ91315.1 - 1.5e-43 148.7 8.4 7.4e-43 146.4 1.6 3.1 3 0 0 3 3 3 1 Unconventional myosin tail, actin- and lipid-binding IQ PF00612.27 KFQ91315.1 - 2.1e-06 27.0 24.4 0.00033 20.2 0.9 6.1 5 0 0 5 5 5 3 IQ calmodulin-binding motif AAA_16 PF13191.6 KFQ91315.1 - 0.0073 16.7 0.1 0.028 14.8 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFQ91315.1 - 0.031 14.6 0.0 0.11 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 KFQ91315.1 - 0.039 13.5 0.9 2 7.9 0.0 2.7 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Sigma54_activat PF00158.26 KFQ91315.1 - 0.083 12.6 0.0 1 9.1 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Chorismate_bind PF00425.18 KFQ91315.1 - 0.1 12.1 0.0 15 5.0 0.0 2.5 2 0 0 2 2 2 0 chorismate binding enzyme DUF4441 PF14536.6 KFQ91315.1 - 3.4 7.9 10.2 2.9 8.1 1.3 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4441) Nab1 PF04902.12 KFQ91316.1 - 4e-60 203.3 0.1 7.6e-60 202.4 0.1 1.5 1 0 0 1 1 1 1 Conserved region in Nab1 NCD2 PF04905.13 KFQ91316.1 - 2.1e-56 189.3 1.0 3.9e-56 188.4 1.0 1.4 1 0 0 1 1 1 1 NAB conserved region 2 (NCD2) NCD1 PF04904.13 KFQ91316.1 - 2.7e-41 139.4 0.0 4.5e-41 138.7 0.0 1.4 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) DUF1564 PF07600.11 KFQ91316.1 - 0.12 12.1 0.1 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) tRNA-synt_1b PF00579.25 KFQ91316.1 - 0.15 11.3 0.5 3.8 6.8 0.1 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) NEMP PF10225.9 KFQ91317.1 - 6.1e-79 265.2 8.2 7.9e-79 264.8 8.2 1.1 1 0 0 1 1 1 1 NEMP family DUF5381 PF17353.2 KFQ91317.1 - 4.4 7.0 9.8 1.7 8.4 5.4 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5381) MFS_1_like PF12832.7 KFQ91318.1 - 1.3e-92 310.6 11.8 1.7e-92 310.2 11.8 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFQ91318.1 - 2.4e-30 105.7 24.7 1.3e-16 60.5 11.5 3.4 2 2 1 3 3 3 3 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KFQ91318.1 - 1e-07 31.3 7.0 1e-07 31.3 7.0 3.6 3 1 0 3 3 3 1 Nucleoside H+ symporter LacY_symp PF01306.19 KFQ91318.1 - 1.2e-06 27.6 18.2 0.0016 17.3 3.8 3.2 3 0 0 3 3 3 3 LacY proton/sugar symporter MFS_2 PF13347.6 KFQ91318.1 - 0.00027 19.6 17.4 0.033 12.7 0.0 3.6 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_3 PF05977.13 KFQ91318.1 - 0.00088 17.8 2.0 0.0011 17.5 0.7 1.7 2 0 0 2 2 2 1 Transmembrane secretion effector DUF5316 PF17247.2 KFQ91318.1 - 0.088 12.8 0.0 0.32 11.0 0.0 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5316) OppC_N PF12911.7 KFQ91318.1 - 1.5 8.8 11.3 3.6 7.6 0.0 4.0 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C ISET-FN3_linker PF16625.5 KFQ91318.1 - 5.9 7.5 9.1 2.8 8.6 3.1 2.6 2 0 0 2 2 2 0 Unstructured linking region I-set and fnIII on Brother of CDO ECH_2 PF16113.5 KFQ91319.1 - 2.2e-138 461.3 0.0 2.8e-138 461.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KFQ91319.1 - 4.6e-32 111.3 0.0 1.6e-29 103.0 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SmAKAP PF15127.6 KFQ91320.1 - 4.2e-26 92.0 0.2 7.8e-26 91.1 0.2 1.4 1 1 0 1 1 1 1 Small membrane A-kinase anchor protein TGFb_propeptide PF00688.18 KFQ91321.1 - 7.9e-34 117.5 0.0 1e-33 117.1 0.0 1.1 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 KFQ91321.1 - 1.7e-28 99.6 0.9 4.5e-28 98.3 0.9 1.8 1 0 0 1 1 1 1 Transforming growth factor beta like domain LydB PF16084.5 KFQ91321.1 - 0.094 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 LydA-holin antagonist DNA_mis_repair PF01119.19 KFQ91323.1 - 8.6e-24 83.5 0.0 3.8e-23 81.4 0.0 2.2 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KFQ91323.1 - 3.2e-12 46.4 0.2 7.8e-12 45.2 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KFQ91323.1 - 1.6e-08 35.0 0.2 3.5e-08 33.9 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HMG_box PF00505.19 KFQ91323.1 - 0.00057 20.2 4.0 0.00057 20.2 4.0 2.8 3 1 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFQ91323.1 - 0.00097 19.7 2.5 0.0028 18.2 2.5 1.8 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 KFQ91323.1 - 0.025 14.5 0.1 0.086 12.8 0.0 1.9 2 0 0 2 2 2 0 CHDNT (NUC034) domain Ribosomal_S4 PF00163.19 KFQ91323.1 - 0.043 14.7 0.4 0.26 12.2 0.2 2.4 2 0 0 2 2 2 0 Ribosomal protein S4/S9 N-terminal domain ORMDL PF04061.14 KFQ91324.1 - 6.1e-54 181.5 2.5 6.8e-54 181.3 2.5 1.0 1 0 0 1 1 1 1 ORMDL family Peptidase_M22 PF00814.25 KFQ91325.1 - 7.2e-57 193.1 1.5 8.6e-57 192.9 1.5 1.1 1 0 0 1 1 1 1 Glycoprotease family Asn_synthase PF00733.21 KFQ91326.1 - 2.1e-19 70.4 0.0 1.8e-07 31.2 0.0 3.2 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 KFQ91326.1 - 1.4e-06 28.3 0.0 7.6e-06 25.9 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KFQ91326.1 - 0.0017 18.6 0.0 0.0067 16.6 0.0 1.9 2 1 0 2 2 2 1 Glutamine amidotransferase domain ATP_bind_3 PF01171.20 KFQ91326.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 PP-loop family QueC PF06508.13 KFQ91326.1 - 0.15 11.6 0.0 0.35 10.3 0.0 1.6 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC FPN1 PF06963.12 KFQ91327.1 - 1.2e-186 620.6 14.8 1.4e-186 620.4 14.8 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) WD40 PF00400.32 KFQ91328.1 - 3.5e-13 49.8 18.3 0.00043 21.0 0.2 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ91328.1 - 1.9e-05 24.8 0.3 2.4 8.5 0.0 5.4 4 1 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain COLFI PF01410.18 KFQ91329.1 - 2.2e-54 184.2 0.0 2.4e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain COLFI PF01410.18 KFQ91330.1 - 4.2e-55 186.6 0.0 4.6e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain SNARE PF05739.19 KFQ91330.1 - 0.085 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 SNARE domain Pep_M12B_propep PF01562.19 KFQ91331.1 - 1.8e-35 122.2 0.7 3.6e-35 121.2 0.7 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_spacer1 PF05986.14 KFQ91331.1 - 4.2e-34 117.0 0.0 8.6e-34 116.0 0.0 1.5 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.19 KFQ91331.1 - 3.1e-32 110.5 79.2 4.2e-11 42.9 7.4 7.9 6 1 0 6 6 6 6 Thrombospondin type 1 domain Reprolysin PF01421.19 KFQ91331.1 - 1.5e-28 100.0 0.1 3.1e-28 99.1 0.1 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 KFQ91331.1 - 4.8e-20 71.9 8.3 4.8e-20 71.9 8.3 6.2 5 3 1 6 6 6 2 ADAM cysteine-rich domain PLAC PF08686.11 KFQ91331.1 - 1.1e-10 42.1 8.8 1.1e-10 42.1 8.8 5.2 4 0 0 4 4 4 1 PLAC (protease and lacunin) domain Reprolysin_5 PF13688.6 KFQ91331.1 - 1.5e-10 41.6 0.8 3.7e-10 40.3 0.1 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KFQ91331.1 - 3.3e-09 36.9 0.1 6.9e-09 35.9 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 KFQ91331.1 - 1.2e-06 29.0 0.1 3.8e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFQ91331.1 - 0.00038 20.2 0.1 0.00088 19.0 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pribosyltran PF00156.27 KFQ91333.1 - 0.00073 19.1 0.0 0.00092 18.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NUDIX PF00293.28 KFQ91334.1 - 5.4e-13 49.1 0.0 8.5e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain ADH_zinc_N_2 PF13602.6 KFQ91335.1 - 6.2e-14 53.2 0.0 1.5e-13 52.0 0.0 1.7 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFQ91335.1 - 5.2e-10 39.4 0.0 1.1e-09 38.3 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFQ91335.1 - 4e-08 33.1 0.0 8.5e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Lectin_C PF00059.21 KFQ91336.1 - 4.1e-18 66.1 0.2 6.7e-18 65.4 0.2 1.3 1 0 0 1 1 1 1 Lectin C-type domain Chordopox_A33R PF05966.12 KFQ91336.1 - 0.0022 17.3 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Chordopoxvirus A33R protein BUD22 PF09073.10 KFQ91336.1 - 0.076 12.3 1.3 0.087 12.2 1.3 1.1 1 0 0 1 1 1 0 BUD22 GPS PF01825.21 KFQ91336.1 - 0.15 12.7 0.8 0.37 11.4 0.8 1.7 1 0 0 1 1 1 0 GPCR proteolysis site, GPS, motif adh_short PF00106.25 KFQ91337.1 - 4.2e-28 98.1 0.0 1.8e-23 83.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFQ91337.1 - 1.7e-17 63.7 0.0 1.3e-15 57.6 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFQ91337.1 - 8.1e-10 38.9 0.1 1.2e-09 38.3 0.1 1.2 1 0 0 1 1 1 1 KR domain WW PF00397.26 KFQ91337.1 - 2.4e-08 33.9 5.7 3.5e-07 30.2 0.4 2.6 2 0 0 2 2 2 2 WW domain Epimerase PF01370.21 KFQ91337.1 - 0.0049 16.3 0.0 0.0067 15.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFQ91337.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain PerB PF06590.11 KFQ91337.1 - 0.12 12.8 0.0 0.29 11.7 0.0 1.6 2 0 0 2 2 2 0 PerB protein Robl_LC7 PF03259.17 KFQ91338.1 - 8.2e-18 64.0 0.0 8.9e-18 63.9 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain Cmc1 PF08583.10 KFQ91339.1 - 5.2e-17 61.6 3.9 5.9e-17 61.4 3.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF755 PF05501.11 KFQ91339.1 - 0.033 14.5 0.4 0.036 14.3 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) CENP-N PF05238.13 KFQ91340.1 - 5.5e-73 246.6 3.9 1e-71 242.4 3.9 2.0 1 1 0 1 1 1 1 Kinetochore protein CHL4 like zf-C2H2 PF00096.26 KFQ91341.1 - 0.032 14.7 13.9 1.1 9.8 0.2 4.5 2 1 1 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ91341.1 - 0.073 13.9 12.8 2.3 9.3 0.5 4.3 2 1 1 3 3 3 0 C2H2-type zinc finger GCV_H PF01597.19 KFQ91342.1 - 5.9e-44 148.9 0.0 6.7e-44 148.7 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein RPE65 PF03055.15 KFQ91343.1 - 1.9e-120 403.2 2.2 2.2e-120 403.0 2.2 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein LRR_4 PF12799.7 KFQ91344.1 - 7e-06 26.3 10.2 0.0083 16.5 0.2 4.5 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFQ91344.1 - 2.8e-05 23.8 2.2 0.12 12.1 0.2 3.1 2 0 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 KFQ91344.1 - 0.0051 16.8 1.1 5.1 7.4 0.0 4.3 4 0 0 4 4 4 1 Leucine Rich repeat PH PF00169.29 KFQ91344.1 - 0.04 14.4 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 PH domain Microtub_bd PF16796.5 KFQ91344.1 - 0.1 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Microtubule binding 3Beta_HSD PF01073.19 KFQ91345.1 - 5.3e-71 238.9 0.0 6.9e-71 238.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFQ91345.1 - 2e-25 89.7 0.0 2.6e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFQ91345.1 - 4.1e-11 42.5 0.0 5.7e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KFQ91345.1 - 3.5e-09 36.5 0.0 2.5e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KFQ91345.1 - 1.6e-07 30.8 0.5 6e-07 28.9 0.5 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KFQ91345.1 - 1.9e-07 30.5 0.0 4.1e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KFQ91345.1 - 0.0002 21.3 0.0 0.00027 20.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KFQ91346.1 - 3.2e-42 144.2 0.0 3.8e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFQ91346.1 - 3.8e-29 101.9 0.0 4.9e-29 101.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFQ91346.1 - 2.6e-05 24.2 0.0 3.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFQ91346.1 - 0.00032 20.1 0.0 0.00052 19.5 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Acetyltransf_2 PF00797.17 KFQ91347.1 - 4.3e-92 308.3 0.1 4.9e-92 308.1 0.1 1.0 1 0 0 1 1 1 1 N-acetyltransferase Acetyltransf_2 PF00797.17 KFQ91348.1 - 9.8e-90 300.5 0.1 1.1e-89 300.4 0.1 1.0 1 0 0 1 1 1 1 N-acetyltransferase Acetyltransf_2 PF00797.17 KFQ91349.1 - 6.7e-93 310.9 0.7 7.6e-93 310.7 0.7 1.0 1 0 0 1 1 1 1 N-acetyltransferase MPP6 PF10175.9 KFQ91350.1 - 6.4e-35 120.5 3.7 6.4e-35 120.5 3.7 1.5 2 0 0 2 2 2 1 M-phase phosphoprotein 6 DUF5085 PF16895.5 KFQ91350.1 - 0.0091 16.3 0.4 0.019 15.3 0.4 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF5085) Ku_C PF03730.14 KFQ91350.1 - 0.033 14.9 1.0 0.033 14.9 1.0 1.6 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm DUF3864 PF12980.7 KFQ91350.1 - 0.08 13.3 0.4 0.17 12.3 0.1 1.8 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3864) Cadherin PF00028.17 KFQ91351.1 - 4.8e-71 235.3 2.1 5.3e-20 71.7 0.0 4.3 4 0 0 4 4 4 4 Cadherin domain Cadherin_3 PF16184.5 KFQ91351.1 - 3e-12 46.5 4.3 0.00032 20.6 0.2 5.2 5 0 0 5 5 5 4 Cadherin-like Cadherin_4 PF17803.1 KFQ91351.1 - 7.5e-06 26.5 17.3 2.4e-05 24.9 2.8 3.9 4 0 0 4 4 4 2 Bacterial cadherin-like domain Big_9 PF17963.1 KFQ91351.1 - 4.2e-05 24.2 2.8 4.2e-05 24.2 2.8 3.3 3 0 0 3 3 3 1 Bacterial Ig domain CUB PF00431.20 KFQ91352.1 - 4.7e-287 931.4 0.0 3.5e-25 88.5 0.0 12.3 12 0 0 12 12 12 12 CUB domain Sushi PF00084.20 KFQ91352.1 - 6.9e-235 759.9 161.9 7.8e-11 42.4 0.3 27.5 27 0 0 27 27 27 27 Sushi repeat (SCR repeat) CUB_2 PF02408.20 KFQ91352.1 - 7.9e-23 80.5 12.6 0.025 14.3 0.3 11.3 11 0 0 11 11 11 8 CUB-like domain HRM PF02793.22 KFQ91352.1 - 0.0061 16.8 73.2 0.65 10.3 0.5 15.4 15 1 1 16 16 16 7 Hormone receptor domain Syntaphilin PF15290.6 KFQ91357.1 - 4e-124 414.3 17.9 8.9e-124 413.2 17.9 1.6 1 0 0 1 1 1 1 Golgi-localised syntaxin-1-binding clamp FPP PF05911.11 KFQ91357.1 - 0.0017 16.7 15.1 0.0017 16.7 15.1 1.5 2 0 0 2 2 2 1 Filament-like plant protein, long coiled-coil CALCOCO1 PF07888.11 KFQ91357.1 - 0.0047 15.9 12.1 0.0047 15.9 12.1 1.4 2 0 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like Atg14 PF10186.9 KFQ91357.1 - 0.036 13.1 13.4 0.064 12.3 13.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 KFQ91357.1 - 0.046 13.3 6.8 0.079 12.5 6.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit ArAE_1_C PF11728.8 KFQ91357.1 - 0.047 13.7 9.7 0.099 12.6 9.7 1.5 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain FAM76 PF16046.5 KFQ91357.1 - 0.054 12.8 16.4 0.11 11.9 11.0 2.3 1 1 1 2 2 2 0 FAM76 protein HMMR_N PF15905.5 KFQ91357.1 - 0.12 11.8 18.6 0.45 10.0 18.6 2.0 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF641 PF04859.12 KFQ91357.1 - 0.15 12.4 13.0 0.085 13.2 2.0 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) ERM PF00769.19 KFQ91357.1 - 0.23 11.3 18.0 0.37 10.6 18.0 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF4407 PF14362.6 KFQ91357.1 - 0.31 10.4 5.8 0.47 9.8 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 KFQ91357.1 - 0.31 11.5 20.3 0.57 10.6 20.2 1.5 1 1 0 1 1 1 0 Fez1 HR1 PF02185.16 KFQ91357.1 - 0.31 11.2 15.8 0.049 13.7 1.6 3.2 2 1 1 3 3 3 0 Hr1 repeat TPR_MLP1_2 PF07926.12 KFQ91357.1 - 0.37 10.9 18.8 0.25 11.4 7.4 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein YgaB PF14182.6 KFQ91357.1 - 0.77 10.2 12.1 0.28 11.6 3.9 2.7 1 1 1 2 2 2 0 YgaB-like protein Sec2p PF06428.11 KFQ91357.1 - 0.81 9.7 17.0 0.12 12.4 3.2 3.0 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Sec8_exocyst PF04048.14 KFQ91357.1 - 0.87 9.5 15.8 0.28 11.0 0.4 2.9 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain CC2-LZ PF16516.5 KFQ91357.1 - 0.92 9.9 16.6 1.2 9.5 4.2 2.5 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator PKcGMP_CC PF16808.5 KFQ91357.1 - 1.1 9.2 14.1 0.064 13.1 4.7 3.1 2 2 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HrpB7 PF09486.10 KFQ91357.1 - 2.7 8.3 9.3 8.9 6.7 1.7 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF948 PF06103.11 KFQ91357.1 - 4.5 7.6 6.7 0.92 9.8 1.1 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) LMBR1 PF04791.16 KFQ91357.1 - 4.9 5.9 7.0 7.1 5.4 7.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF745 PF05335.13 KFQ91357.1 - 5.4 6.7 10.2 10 5.8 10.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Spc7 PF08317.11 KFQ91357.1 - 5.5 5.8 19.9 17 4.2 20.0 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF16 PF01519.16 KFQ91357.1 - 5.7 7.5 17.3 2.1e+02 2.5 16.3 2.8 2 1 0 2 2 2 0 Protein of unknown function DUF16 MPS2 PF17060.5 KFQ91357.1 - 5.9 6.1 13.3 14 4.8 13.2 1.5 1 1 0 1 1 1 0 Monopolar spindle protein 2 FapA PF03961.13 KFQ91357.1 - 7.9 5.0 13.2 12 4.4 13.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3395 PF11875.8 KFQ91358.1 - 7.5 6.4 10.8 13 5.6 10.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) EnY2 PF10163.9 KFQ91359.1 - 1.8e-35 121.2 0.6 2e-35 121.0 0.6 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 DUF2294 PF10057.9 KFQ91359.1 - 0.066 13.3 0.3 0.66 10.1 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2294) CS PF04969.16 KFQ91360.1 - 1e-19 71.3 2.3 1.7e-18 67.4 2.0 2.6 2 0 0 2 2 2 1 CS domain 7tm_1 PF00001.21 KFQ91361.1 - 3.8e-51 173.9 25.1 5.2e-51 173.5 25.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ91361.1 - 3.4e-10 39.7 24.4 6.9e-10 38.7 24.4 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFQ91361.1 - 3.7e-08 33.3 24.0 3.7e-08 33.3 24.0 2.4 1 1 2 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFQ91361.1 - 7.6e-06 25.9 19.4 1.5e-05 24.9 12.8 2.2 2 0 0 2 2 2 2 Olfactory receptor ISK_Channel PF02060.15 KFQ91361.1 - 0.033 13.9 0.1 2.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Slow voltage-gated potassium channel Neurensin PF14927.6 KFQ91362.1 - 1.5e-07 31.2 0.0 2.1e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Neurensin TPR_19 PF14559.6 KFQ91363.1 - 8.8e-11 42.2 8.1 9.6e-06 26.0 1.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ91363.1 - 1.1e-10 40.7 9.9 0.00017 21.4 0.5 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ91363.1 - 1.8e-10 40.7 7.1 0.0052 17.5 0.6 5.3 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ91363.1 - 2.4e-07 31.3 2.0 0.61 10.8 0.2 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ91363.1 - 4e-07 29.6 4.5 0.061 13.2 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ91363.1 - 6.5e-05 22.8 10.8 0.051 13.8 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ91363.1 - 0.0041 17.0 1.6 5 7.4 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFQ91363.1 - 0.0044 17.6 6.8 5.8 7.8 0.1 4.9 6 0 0 6 6 4 1 Tetratricopeptide repeat NARP1 PF12569.8 KFQ91363.1 - 0.0058 15.6 4.8 0.0058 15.6 4.8 2.4 1 1 2 3 3 3 1 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 KFQ91363.1 - 0.006 16.7 1.7 0.72 10.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KFQ91363.1 - 0.0073 16.8 8.4 0.23 11.9 0.4 3.1 1 1 1 3 3 3 2 Alkyl sulfatase dimerisation TPR_20 PF14561.6 KFQ91363.1 - 0.029 14.7 1.5 0.55 10.6 0.1 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KFQ91363.1 - 0.078 12.6 0.4 4.5 6.9 0.3 2.6 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) ANAPC3 PF12895.7 KFQ91363.1 - 0.091 13.0 9.9 0.34 11.2 3.4 3.5 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 MyTH4 PF00784.17 KFQ91363.1 - 0.19 12.2 1.5 23 5.5 0.2 3.2 2 1 1 3 3 3 0 MyTH4 domain TPR_17 PF13431.6 KFQ91363.1 - 0.24 11.9 6.0 1.7 9.2 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribonuclease_T2 PF00445.18 KFQ91363.1 - 1.4 9.1 4.5 3.4 7.9 4.5 1.7 1 1 0 1 1 1 0 Ribonuclease T2 family TPR_12 PF13424.6 KFQ91363.1 - 1.5 9.2 12.8 1.1 9.6 1.3 3.8 3 1 0 4 4 3 0 Tetratricopeptide repeat eIF3_N PF09440.10 KFQ91364.1 - 2e-31 109.2 2.4 2e-31 109.2 2.4 2.0 3 0 0 3 3 3 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KFQ91364.1 - 2.4e-19 69.8 0.2 1e-18 67.8 0.0 2.2 3 0 0 3 3 3 1 PCI domain HD_assoc PF13286.6 KFQ91364.1 - 0.05 14.1 1.4 2.2 8.9 0.2 2.6 2 0 0 2 2 2 0 Phosphohydrolase-associated domain CSN8_PSD8_EIF3K PF10075.9 KFQ91364.1 - 0.14 12.2 1.0 0.69 9.9 0.0 2.6 4 0 0 4 4 4 0 CSN8/PSMD8/EIF3K family Furin-like_2 PF15913.5 KFQ91365.1 - 2.9e-42 143.2 23.3 6.1e-42 142.2 23.3 1.5 1 0 0 1 1 1 1 Furin-like repeat, cysteine-rich Acyltransferase PF01553.21 KFQ91366.1 - 1.9e-20 72.9 0.1 4.2e-20 71.7 0.1 1.6 1 0 0 1 1 1 1 Acyltransferase RlmM_FDX PF18125.1 KFQ91366.1 - 0.12 12.9 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 RlmM ferredoxin-like domain Acyltransferase PF01553.21 KFQ91367.1 - 9.4e-11 41.5 0.0 1.7e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Tropomyosin PF00261.20 KFQ91368.1 - 0.0012 18.3 2.9 0.0012 18.3 2.9 2.0 2 0 0 2 2 2 1 Tropomyosin FlaC_arch PF05377.11 KFQ91368.1 - 0.16 12.4 1.6 0.45 11.0 1.6 1.8 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Peptidase_S49_N PF08496.10 KFQ91368.1 - 3.5 7.7 6.3 0.36 10.9 1.1 1.9 1 1 1 2 2 2 0 Peptidase family S49 N-terminal Ribosomal_S18 PF01084.20 KFQ91369.1 - 4.5e-23 81.2 0.0 9.8e-23 80.1 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S18 Glyco_hydro_79n PF03662.14 KFQ91370.1 - 2.5e-26 92.4 0.0 8.2e-26 90.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 79, N-terminal domain UbiA PF01040.18 KFQ91371.1 - 2.7e-52 177.6 9.0 3.1e-52 177.4 9.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF4018 PF13210.6 KFQ91371.1 - 0.011 15.5 0.5 0.038 13.8 0.0 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4018) PLAC8 PF04749.17 KFQ91372.1 - 2.3e-14 54.2 28.2 4.6e-14 53.2 28.2 1.5 1 1 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 KFQ91373.1 - 6.7e-14 52.7 18.0 1.4e-13 51.7 18.0 1.5 1 1 0 1 1 1 1 PLAC8 family ABC2_membrane PF01061.24 KFQ91374.1 - 2.3e-33 115.4 26.0 2.3e-33 115.4 26.0 1.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KFQ91374.1 - 2.8e-22 79.7 0.3 6.5e-22 78.5 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KFQ91374.1 - 4.3e-07 30.1 0.8 0.0032 17.3 0.2 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFQ91374.1 - 6.9e-06 25.6 0.1 0.022 14.2 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFQ91374.1 - 0.00034 21.2 0.0 0.00034 21.2 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 KFQ91374.1 - 0.0026 17.4 0.0 0.0061 16.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFQ91374.1 - 0.0083 16.0 0.2 0.041 13.8 0.0 2.2 3 0 0 3 3 3 1 RsgA GTPase PDR_assoc PF08370.11 KFQ91374.1 - 0.1 12.4 0.1 0.1 12.4 0.1 2.4 2 0 0 2 2 2 0 Plant PDR ABC transporter associated DUF87 PF01935.17 KFQ91374.1 - 0.18 11.9 0.7 0.49 10.5 0.0 2.0 3 0 0 3 3 3 0 Helicase HerA, central domain ABC2_membrane_2 PF12679.7 KFQ91374.1 - 0.26 10.5 20.3 0.056 12.7 14.9 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein PKD_channel PF08016.12 KFQ91375.1 - 3e-160 533.6 19.1 3e-160 533.6 19.1 1.9 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 KFQ91375.1 - 4.7e-24 85.0 31.2 9.9e-24 83.9 29.4 2.1 2 0 0 2 2 2 1 Ion transport protein Osteopontin PF00865.18 KFQ91376.1 - 3.1e-18 66.3 17.2 5.3e-16 59.0 0.8 2.4 1 1 1 2 2 2 2 Osteopontin NOA36 PF06524.12 KFQ91376.1 - 4.1 6.6 5.9 5.1 6.3 5.9 1.1 1 0 0 1 1 1 0 NOA36 protein BSP_II PF05432.11 KFQ91378.1 - 6.8e-58 196.7 70.1 6.3e-33 114.8 57.1 2.0 1 1 1 2 2 2 2 Bone sialoprotein II (BSP-II) UPF0564 PF10595.9 KFQ91378.1 - 0.01 14.9 6.9 0.014 14.5 6.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 CDC27 PF09507.10 KFQ91378.1 - 0.31 10.4 13.5 0.45 9.8 13.5 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 rRNA_processing PF08524.11 KFQ91378.1 - 0.39 10.8 14.3 0.83 9.7 14.3 1.5 1 0 0 1 1 1 0 rRNA processing SAPS PF04499.15 KFQ91378.1 - 0.55 8.9 10.9 0.61 8.8 10.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1387 PF07139.11 KFQ91378.1 - 1.8 8.2 10.6 2.7 7.6 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Presenilin PF01080.17 KFQ91378.1 - 5.2 5.7 12.3 7.3 5.2 12.3 1.4 1 0 0 1 1 1 0 Presenilin eIF3_subunit PF08597.10 KFQ91378.1 - 7.3 6.4 23.1 14 5.5 23.1 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DMP1 PF07263.11 KFQ91379.1 - 5.2e-13 48.8 44.6 6e-13 48.5 44.6 1.1 1 0 0 1 1 1 1 Dentin matrix protein 1 (DMP1) SPARC_Ca_bdg PF10591.9 KFQ91380.1 - 1.1e-41 141.7 1.1 1.8e-41 141.0 1.1 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_1 PF00050.21 KFQ91380.1 - 1.4e-13 50.6 6.8 1.4e-13 50.6 6.8 2.2 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain FOLN PF09289.10 KFQ91380.1 - 2.3e-09 37.2 9.8 2.3e-09 37.2 9.8 2.7 4 0 0 4 4 4 1 Follistatin/Osteonectin-like EGF domain Kazal_2 PF07648.15 KFQ91380.1 - 6.1e-08 32.7 6.1 6.1e-08 32.7 6.1 2.7 2 1 1 3 3 3 1 Kazal-type serine protease inhibitor domain EF-hand_1 PF00036.32 KFQ91380.1 - 0.076 12.6 0.2 0.81 9.4 0.1 2.3 2 0 0 2 2 2 0 EF hand NUDIX PF00293.28 KFQ91381.1 - 4.8e-09 36.3 0.3 9.1e-09 35.5 0.3 1.5 1 1 0 1 1 1 1 NUDIX domain L27 PF02828.16 KFQ91381.1 - 0.16 11.7 0.4 0.28 11.0 0.4 1.3 1 0 0 1 1 1 0 L27 domain TIMP PF00965.17 KFQ91382.1 - 1.3e-56 191.3 2.3 1.4e-56 191.1 2.3 1.0 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.21 KFQ91382.1 - 0.018 14.8 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 UNC-6/NTR/C345C module Apyrase PF06079.11 KFQ91383.1 - 1.7e-84 283.5 1.0 2e-84 283.2 1.0 1.0 1 0 0 1 1 1 1 Apyrase C1q PF00386.21 KFQ91384.1 - 5.8e-38 130.0 1.4 7.2e-38 129.7 1.4 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFQ91384.1 - 2.2e-08 33.7 12.8 3.2e-08 33.2 12.8 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Glyco_hydro_85 PF03644.13 KFQ91385.1 - 5.9e-97 324.7 0.1 7.8e-97 324.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Fox-1_C PF12414.8 KFQ91386.1 - 1.5e-44 150.3 22.1 1.5e-44 150.3 22.1 2.1 3 0 0 3 3 3 1 Calcitonin gene-related peptide regulator C terminal RRM_1 PF00076.22 KFQ91386.1 - 8.4e-19 67.2 1.5 1.1e-18 66.7 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFQ91386.1 - 0.043 13.4 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SH2 PF00017.24 KFQ91387.1 - 5.1e-16 58.5 0.1 1.3e-15 57.2 0.1 1.8 1 0 0 1 1 1 1 SH2 domain PSCyt2 PF07583.11 KFQ91387.1 - 1.2 9.0 9.7 0.055 13.4 3.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1549) Arm PF00514.23 KFQ91388.1 - 7.4e-23 79.8 18.9 2.2e-07 30.7 0.3 9.0 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KFQ91388.1 - 4.4e-09 36.6 14.6 0.15 12.5 1.3 5.8 2 2 1 5 5 5 4 HEAT repeats Proteasom_PSMB PF10508.9 KFQ91388.1 - 2.2e-05 23.2 2.1 2.2e-05 23.2 2.1 3.1 2 2 1 3 3 3 2 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.6 KFQ91388.1 - 3.1e-05 24.4 6.1 0.3 11.6 0.0 5.8 5 1 1 6 6 6 2 HEAT-like repeat V-ATPase_H_C PF11698.8 KFQ91388.1 - 0.00019 21.5 13.7 0.00052 20.1 0.3 4.6 4 1 2 6 6 6 1 V-ATPase subunit H V-ATPase_H_N PF03224.14 KFQ91388.1 - 0.00065 19.1 18.3 0.11 11.8 1.0 5.0 1 1 1 4 4 4 3 V-ATPase subunit H RTTN_N PF14726.6 KFQ91388.1 - 0.0013 19.5 11.3 0.12 13.1 0.1 4.5 2 2 2 4 4 4 2 Rotatin, an armadillo repeat protein, centriole functioning HEAT PF02985.22 KFQ91388.1 - 0.0069 16.5 10.0 9.9 6.7 0.1 6.8 9 0 0 9 9 9 1 HEAT repeat DUF2711 PF10924.8 KFQ91388.1 - 0.02 14.5 1.0 0.033 13.8 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2711) Rcd1 PF04078.13 KFQ91388.1 - 0.04 13.2 8.0 0.31 10.3 0.1 3.7 3 1 0 4 4 4 0 Cell differentiation family, Rcd1-like Vps39_1 PF10366.9 KFQ91388.1 - 0.049 13.9 0.5 0.049 13.9 0.5 3.0 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 1 Antirestrict PF03230.13 KFQ91388.1 - 0.14 12.3 0.4 21 5.2 0.0 3.4 2 1 1 3 3 3 0 Antirestriction protein Imm30 PF15565.6 KFQ91388.1 - 0.33 11.1 4.6 24 5.1 0.1 4.0 3 1 0 3 3 3 0 Immunity protein 30 Tetraspanin PF00335.20 KFQ91389.1 - 1.6e-53 181.8 5.8 1.8e-53 181.6 5.8 1.0 1 0 0 1 1 1 1 Tetraspanin family Phage_holin_3_6 PF07332.11 KFQ91389.1 - 0.034 14.2 0.4 0.034 14.2 0.4 2.9 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III KH_6 PF15985.5 KFQ91391.1 - 6.6e-17 61.6 0.0 1e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 KH domain Dpy-30 PF05186.13 KFQ91392.1 - 2.1e-13 49.7 0.0 2.4e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Dpy-30 motif RIIa PF02197.17 KFQ91392.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit S-AdoMet_synt_C PF02773.16 KFQ91393.1 - 2.1e-68 228.6 0.1 4.3e-68 227.6 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KFQ91393.1 - 2.4e-46 156.9 0.0 4.5e-46 156.0 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KFQ91393.1 - 8.7e-44 148.2 0.8 1.3e-43 147.7 0.1 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 KFQ91393.1 - 0.035 12.9 0.2 0.085 11.6 0.2 1.6 1 1 1 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) Lectin_C PF00059.21 KFQ91395.1 - 4.4e-18 66.0 0.2 5.1e-18 65.8 0.2 1.1 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 KFQ91396.1 - 4.4e-23 82.1 0.2 5e-23 81.9 0.2 1.0 1 0 0 1 1 1 1 Lectin C-type domain DUF5075 PF16825.5 KFQ91396.1 - 0.016 14.9 0.1 0.018 14.8 0.1 1.3 1 1 0 1 1 1 0 IGP family C-type lectin domain RasGEF PF00617.19 KFQ91397.1 - 1.9e-46 158.5 3.2 1.9e-46 158.5 3.2 2.2 2 1 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KFQ91397.1 - 1.2e-12 47.9 0.4 4.6e-12 46.1 0.2 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif H2TH PF06831.14 KFQ91397.1 - 0.062 13.3 0.0 24 5.0 0.0 3.0 2 0 0 2 2 2 0 Formamidopyrimidine-DNA glycosylase H2TH domain VHS PF00790.19 KFQ91397.1 - 0.088 12.7 1.7 0.99 9.2 0.2 2.3 1 1 1 2 2 2 0 VHS domain RRT14 PF17075.5 KFQ91397.1 - 0.16 12.1 4.0 0.13 12.4 2.4 1.6 2 0 0 2 2 2 0 Regular of rDNA transcription protein 14 CHGN PF05679.16 KFQ91398.1 - 4.9e-84 283.0 0.1 6.4e-84 282.6 0.1 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 KFQ91398.1 - 3e-08 33.2 0.2 7.2e-08 32.0 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase KfrA_N PF11740.8 KFQ91398.1 - 0.00064 20.4 0.5 0.0011 19.6 0.5 1.3 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term Glyco_tranf_2_2 PF10111.9 KFQ91398.1 - 0.0026 17.3 0.3 1.1 8.7 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Atg14 PF10186.9 KFQ91398.1 - 0.043 12.9 3.1 0.068 12.3 3.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fmp27_WPPW PF10359.9 KFQ91398.1 - 0.11 11.3 1.7 0.15 10.9 1.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain FlxA PF14282.6 KFQ91398.1 - 0.15 12.0 6.0 0.3 11.1 6.0 1.5 1 0 0 1 1 1 0 FlxA-like protein Allexi_40kDa PF05549.11 KFQ91398.1 - 0.17 11.4 0.5 0.28 10.7 0.5 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Csm1_N PF18504.1 KFQ91398.1 - 0.17 12.2 4.8 0.38 11.1 4.4 1.8 2 0 0 2 2 1 0 Csm1 N-terminal domain Fib_alpha PF08702.10 KFQ91398.1 - 0.18 12.0 2.9 0.37 11.0 2.9 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Prefoldin PF02996.17 KFQ91398.1 - 0.32 10.9 3.8 0.9 9.5 3.8 1.7 1 0 0 1 1 1 0 Prefoldin subunit DUF4140 PF13600.6 KFQ91398.1 - 0.92 10.0 3.4 1.9 8.9 3.4 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.6 KFQ91398.1 - 1.5 8.1 6.8 0.05 13.0 0.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Cnn_1N PF07989.11 KFQ91398.1 - 4.2 7.6 8.7 1.9 8.7 6.1 1.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Uso1_p115_C PF04871.13 KFQ91398.1 - 9.1 6.7 17.2 0.068 13.5 5.8 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Pkinase_Tyr PF07714.17 KFQ91399.1 - 2e-104 348.4 0.0 2.9e-104 347.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RET_CLD3 PF17812.1 KFQ91399.1 - 3.2e-54 182.1 0.1 7.1e-54 181.0 0.1 1.6 1 0 0 1 1 1 1 RET Cadherin like domain 3 RET_CLD1 PF17756.1 KFQ91399.1 - 7.7e-53 178.1 0.0 2.3e-51 173.3 0.0 3.2 3 0 0 3 3 3 1 RET Cadherin like domain 1 Pkinase PF00069.25 KFQ91399.1 - 5.6e-46 157.0 0.0 1.2e-45 156.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain RET_CLD4 PF17813.1 KFQ91399.1 - 3.4e-45 152.6 0.2 2e-44 150.2 0.1 2.4 2 0 0 2 2 2 1 RET Cadherin like domain 4 Cadherin PF00028.17 KFQ91399.1 - 4.9e-18 65.4 0.1 8.9e-09 35.7 0.0 5.0 4 1 0 4 4 4 2 Cadherin domain Cadherin_2 PF08266.12 KFQ91399.1 - 0.01 15.6 0.3 1 9.3 0.0 2.9 3 0 0 3 3 3 0 Cadherin-like RIO1 PF01163.22 KFQ91399.1 - 0.03 13.9 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 KFQ91399.1 - 0.085 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KFQ91399.1 - 0.1 11.5 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain RIBIOP_C PF04950.12 KFQ91400.1 - 1.5e-96 323.3 0.0 1.5e-96 323.3 0.0 3.0 3 0 0 3 3 3 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KFQ91400.1 - 9.9e-31 105.7 0.3 5.1e-30 103.4 0.0 2.6 2 0 0 2 2 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 KFQ91400.1 - 3.8e-06 26.6 0.0 0.00049 19.7 0.0 3.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFQ91400.1 - 0.0006 19.9 0.2 0.0072 16.4 0.1 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFQ91400.1 - 0.011 16.2 0.7 0.032 14.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 KFQ91400.1 - 0.011 16.1 0.1 0.034 14.6 0.1 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Olfactory_mark PF06554.12 KFQ91400.1 - 0.032 14.0 0.3 0.17 11.6 0.1 2.3 2 0 0 2 2 2 0 Olfactory marker protein RNA_helicase PF00910.22 KFQ91400.1 - 0.042 14.2 0.2 0.31 11.5 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 KFQ91400.1 - 0.055 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Gly_acyl_tr_C PF08444.10 KFQ91400.1 - 0.1 12.8 0.0 0.49 10.6 0.0 2.2 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region ABC_tran PF00005.27 KFQ91400.1 - 1.1 9.7 0.0 1.1 9.7 0.0 3.4 4 0 0 4 4 4 0 ABC transporter Homeodomain PF00046.29 KFQ91401.1 - 3.3e-20 71.7 0.4 3.7e-20 71.5 0.4 1.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ91401.1 - 1.7e-05 24.6 0.4 7.6e-05 22.5 0.1 1.9 2 0 0 2 2 2 1 Homeobox KN domain DUF4499 PF14934.6 KFQ91402.1 - 2.6e-29 101.4 7.5 2.9e-29 101.2 7.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) PALP PF00291.25 KFQ91403.1 - 3.8e-60 203.8 0.2 4.5e-60 203.6 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT_6 PF13740.6 KFQ91403.1 - 0.0061 16.5 0.0 0.018 15.0 0.0 1.8 1 0 0 1 1 1 1 ACT domain PLAC9 PF15205.6 KFQ91404.1 - 2.5e-14 53.4 0.1 2.6e-14 53.3 0.1 1.0 1 0 0 1 1 1 1 Placenta-specific protein 9 Annexin PF00191.20 KFQ91405.1 - 3.9e-103 337.6 13.2 6.7e-26 90.1 0.3 4.1 4 0 0 4 4 4 4 Annexin Myb_DNA-bind_7 PF15963.5 KFQ91405.1 - 0.025 14.4 0.6 9.7 6.2 0.0 3.1 3 0 0 3 3 3 0 Myb DNA-binding like zf-3CxxC_2 PF17180.4 KFQ91406.1 - 3.3e-27 95.0 10.2 3.3e-27 95.0 10.2 1.8 2 0 0 2 2 2 1 Zinc-binding domain zf-CCHC_2 PF13696.6 KFQ91406.1 - 2.8e-11 43.0 6.2 2.8e-11 43.0 6.2 3.1 4 0 0 4 4 4 1 Zinc knuckle UPF0515 PF15135.6 KFQ91406.1 - 8.6e-05 22.0 4.8 0.00011 21.7 4.8 1.3 1 0 0 1 1 1 1 Uncharacterised protein UPF0515 zf-3CxxC PF13695.6 KFQ91406.1 - 0.019 15.4 16.6 0.43 11.1 15.4 2.9 2 1 0 2 2 2 0 Zinc-binding domain zf-CHY PF05495.12 KFQ91406.1 - 0.13 12.7 11.6 0.99 9.9 2.9 2.4 2 0 0 2 2 2 0 CHY zinc finger Cytochrom_c3_2 PF14537.6 KFQ91406.1 - 6.5 7.3 10.9 27 5.3 11.0 1.9 1 1 1 2 2 2 0 Cytochrome c3 Pro_isomerase PF00160.21 KFQ91407.1 - 2.8e-46 157.7 0.2 3e-46 157.6 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-MIZ PF02891.20 KFQ91408.1 - 3.5e-23 81.1 4.5 3.5e-23 81.1 4.5 2.3 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KFQ91408.1 - 6.1e-06 26.0 1.2 6.1e-06 26.0 1.2 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Ribosomal_S24e PF01282.19 KFQ91410.1 - 6.8e-46 154.1 0.4 1.3e-45 153.3 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e RNA_pol_Rpb1_1 PF04997.12 KFQ91411.1 - 4.6e-95 318.6 1.6 7.6e-95 317.8 1.6 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KFQ91411.1 - 1.6e-88 296.6 0.2 2.4e-88 296.0 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KFQ91411.1 - 5e-75 251.3 0.1 8.9e-75 250.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KFQ91411.1 - 5.1e-42 143.5 0.0 9.8e-41 139.3 0.0 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KFQ91411.1 - 2.2e-32 111.2 0.0 8.1e-32 109.4 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Chordopox_RPO7 PF05864.12 KFQ91411.1 - 0.82 10.0 2.8 61 4.0 0.2 3.5 3 0 0 3 3 3 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) BK_channel_a PF03493.18 KFQ91412.1 - 2.3e-33 114.3 0.1 5.1e-33 113.2 0.1 1.6 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 KFQ91412.1 - 3.9e-18 65.6 19.1 7.7e-18 64.6 19.1 1.4 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFQ91412.1 - 3.7e-14 52.5 2.9 3.7e-14 52.5 2.9 2.6 2 0 0 2 2 2 1 Ion channel TrkA_N PF02254.18 KFQ91412.1 - 1.7e-05 25.0 0.1 0.00015 22.0 0.0 2.3 2 0 0 2 2 2 1 TrkA-N domain Lig_chan PF00060.26 KFQ91412.1 - 0.14 12.0 3.1 0.89 9.4 0.7 2.5 2 0 0 2 2 2 0 Ligand-gated ion channel SR-25 PF10500.9 KFQ91412.1 - 6 6.4 13.0 9.8 5.7 13.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Exo_endo_phos PF03372.23 KFQ91413.1 - 9.1e-09 35.2 1.4 1.1e-08 34.9 1.4 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KFQ91413.1 - 0.16 11.8 0.0 3.8 7.4 0.0 2.0 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase zf-C2H2 PF00096.26 KFQ91414.1 - 1.7e-07 31.3 122.9 0.0013 19.1 7.9 14.7 15 0 0 15 15 15 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ91414.1 - 7.1e-05 23.3 131.8 0.13 13.2 6.3 15.7 15 0 0 15 15 15 10 C2H2-type zinc finger zf-met PF12874.7 KFQ91414.1 - 0.013 15.9 1.3 0.013 15.9 1.3 9.7 10 0 0 10 10 10 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KFQ91414.1 - 0.041 14.5 65.8 0.17 12.6 0.6 12.4 10 3 3 13 13 13 0 FOXP coiled-coil domain Peptidase_M48 PF01435.18 KFQ91415.1 - 2.5e-71 239.5 0.0 3.4e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M48_N PF16491.5 KFQ91415.1 - 1.4e-68 230.4 4.1 1.4e-68 230.4 4.1 1.7 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices DUF4710 PF15828.5 KFQ91415.1 - 0.056 13.6 1.3 0.34 11.1 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) Amino_oxidase PF01593.24 KFQ91416.1 - 5e-136 454.6 0.0 3.9e-135 451.7 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 KFQ91416.1 - 6e-18 65.0 0.3 3.5e-17 62.5 0.0 2.4 3 0 0 3 3 2 1 SWIRM domain NAD_binding_8 PF13450.6 KFQ91416.1 - 3.9e-14 52.6 0.7 8.5e-14 51.5 0.7 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFQ91416.1 - 6.3e-08 32.6 0.0 3.1e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFQ91416.1 - 3.8e-06 26.3 0.1 1.9e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KFQ91416.1 - 6.9e-06 25.5 0.4 1.9e-05 24.1 0.4 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KFQ91416.1 - 4.1e-05 22.8 0.9 8.3e-05 21.8 0.6 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KFQ91416.1 - 5.5e-05 23.7 0.2 5.5e-05 23.7 0.2 3.1 4 0 0 4 4 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFQ91416.1 - 0.00091 18.6 0.3 0.0016 17.7 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KFQ91416.1 - 0.00099 17.9 0.4 0.00099 17.9 0.4 2.2 1 1 1 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KFQ91416.1 - 0.0015 17.8 0.1 0.0027 17.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KFQ91416.1 - 0.0015 17.9 0.2 0.015 14.6 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFQ91416.1 - 0.0059 16.0 2.3 0.0059 16.0 2.3 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KFQ91416.1 - 0.02 14.2 0.2 0.074 12.4 0.1 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KFQ91416.1 - 0.059 12.4 5.5 0.12 11.4 0.3 2.2 1 1 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KFQ91416.1 - 0.1 11.6 0.1 0.19 10.7 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein MCRA PF06100.11 KFQ91416.1 - 0.11 11.3 0.4 0.22 10.2 0.1 1.7 1 1 0 1 1 1 0 MCRA family IlvN PF07991.12 KFQ91416.1 - 0.11 12.0 0.5 0.41 10.2 0.2 1.9 1 1 1 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain MutS_IV PF05190.18 KFQ91416.1 - 0.16 12.3 3.1 1.6 9.1 0.6 2.6 2 0 0 2 2 2 0 MutS family domain IV Snapin_Pallidin PF14712.6 KFQ91416.1 - 0.58 10.6 7.2 7.7 7.0 7.2 2.4 1 1 0 1 1 1 0 Snapin/Pallidin DASH_Dad3 PF08656.10 KFQ91416.1 - 0.8 9.8 3.9 7.8 6.7 0.1 2.9 3 0 0 3 3 3 0 DASH complex subunit Dad3 DivIC PF04977.15 KFQ91416.1 - 1.1 9.0 7.5 16 5.3 0.1 2.8 2 0 0 2 2 2 0 Septum formation initiator DUF4298 PF14131.6 KFQ91416.1 - 3.9 7.5 8.3 3.4 7.7 0.7 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) MRPL52 PF18699.1 KFQ91416.1 - 5.7 7.2 10.9 0.25 11.6 3.8 2.4 2 1 0 2 2 2 0 Mitoribosomal protein mL52 AATF-Che1 PF13339.6 KFQ91416.1 - 7.1 7.3 9.7 2.6 8.7 5.8 2.3 2 2 0 2 2 2 0 Apoptosis antagonizing transcription factor HD_assoc PF13286.6 KFQ91417.1 - 0.018 15.5 0.4 0.14 12.8 0.3 2.6 2 0 0 2 2 2 0 Phosphohydrolase-associated domain Pantoate_ligase PF02569.15 KFQ91417.1 - 0.37 10.0 5.3 1.2 8.3 5.3 1.9 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase Trimer_CC PF08954.11 KFQ91417.1 - 2 8.0 21.5 0.34 10.5 0.2 5.0 4 0 0 4 4 4 0 Trimerisation motif DASH_Dam1 PF08653.10 KFQ91417.1 - 5.5 6.9 14.7 18 5.2 0.2 4.6 4 0 0 4 4 4 0 DASH complex subunit Dam1 7tm_1 PF00001.21 KFQ91418.1 - 1.1e-78 264.2 14.3 1.4e-78 263.9 14.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ91418.1 - 2.1e-11 43.7 9.5 5.4e-11 42.3 9.5 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFQ91418.1 - 1.4e-05 24.8 12.2 1.4e-05 24.8 12.2 2.1 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFQ91418.1 - 2.9e-05 24.0 13.3 0.0014 18.5 10.0 2.5 2 1 0 2 2 2 2 Olfactory receptor RRM_1 PF00076.22 KFQ91419.1 - 5.1e-45 151.2 1.6 1.6e-15 56.6 0.4 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) hnRNP_Q_AcD PF18360.1 KFQ91419.1 - 5e-32 109.7 0.1 1.2e-31 108.4 0.1 1.7 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain RRM_7 PF16367.5 KFQ91419.1 - 4.6e-10 39.5 0.2 0.006 16.7 0.0 4.4 2 2 1 3 3 3 3 RNA recognition motif RRM_5 PF13893.6 KFQ91419.1 - 1.3e-06 28.0 0.0 2.5e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFQ91419.1 - 0.00046 20.0 0.0 0.0065 16.3 0.0 2.7 3 0 0 3 3 3 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KFQ91419.1 - 0.00052 20.0 0.1 1.7 8.8 0.1 3.9 3 1 0 3 3 3 1 Limkain b1 Nup35_RRM_2 PF14605.6 KFQ91419.1 - 0.0071 16.3 0.0 15 5.7 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KFQ91419.1 - 0.012 15.9 1.1 31 4.8 0.0 4.5 3 2 2 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter Spo7_2_N PF15407.6 KFQ91419.1 - 0.074 12.7 0.0 11 5.7 0.0 2.5 2 0 0 2 2 2 0 Sporulation protein family 7 Cep57_MT_bd PF06657.13 KFQ91420.1 - 0.0011 19.4 4.6 0.0015 19.0 4.6 1.3 1 0 0 1 1 1 1 Centrosome microtubule-binding domain of Cep57 DivIC PF04977.15 KFQ91420.1 - 0.0079 15.9 5.1 0.012 15.3 5.1 1.5 1 1 0 1 1 1 1 Septum formation initiator Phage_lysis PF03245.13 KFQ91420.1 - 0.011 15.9 2.7 0.011 15.9 2.7 1.2 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Fib_alpha PF08702.10 KFQ91420.1 - 0.015 15.5 3.1 0.016 15.4 3.1 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Bcr-Abl_Oligo PF09036.10 KFQ91420.1 - 0.022 14.7 3.2 0.025 14.5 3.2 1.1 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain Csm1_N PF18504.1 KFQ91420.1 - 0.032 14.6 2.6 0.032 14.6 2.6 1.6 1 1 1 2 2 2 0 Csm1 N-terminal domain Val_tRNA-synt_C PF10458.9 KFQ91420.1 - 0.048 14.0 2.5 0.048 14.0 2.5 2.0 1 1 1 2 2 2 0 Valyl tRNA synthetase tRNA binding arm FlaC_arch PF05377.11 KFQ91420.1 - 0.066 13.6 1.0 0.071 13.5 1.0 1.2 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) THOC7 PF05615.13 KFQ91420.1 - 0.073 13.3 7.9 0.075 13.3 7.9 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 IATP PF04568.12 KFQ91420.1 - 0.084 13.3 11.6 0.12 12.8 11.6 1.2 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DUF1192 PF06698.11 KFQ91420.1 - 0.088 12.9 5.8 0.24 11.5 5.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) XhlA PF10779.9 KFQ91420.1 - 0.1 12.8 5.0 0.12 12.6 5.0 1.2 1 0 0 1 1 1 0 Haemolysin XhlA Prefoldin_2 PF01920.20 KFQ91420.1 - 0.12 12.4 8.5 0.13 12.3 8.5 1.1 1 0 0 1 1 1 0 Prefoldin subunit DUF3450 PF11932.8 KFQ91420.1 - 0.23 10.7 2.9 0.23 10.7 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) OmpH PF03938.14 KFQ91420.1 - 0.31 11.4 5.5 0.3 11.4 5.5 1.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Borrelia_P83 PF05262.11 KFQ91420.1 - 0.31 9.5 8.4 0.31 9.5 8.4 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein TMPIT PF07851.13 KFQ91420.1 - 0.34 10.1 4.5 0.33 10.1 4.5 1.0 1 0 0 1 1 1 0 TMPIT-like protein Lipoprotein_20 PF13942.6 KFQ91420.1 - 0.4 10.6 5.7 0.45 10.4 5.7 1.0 1 0 0 1 1 1 0 YfhG lipoprotein DUF4407 PF14362.6 KFQ91420.1 - 0.43 9.9 2.8 0.39 10.0 2.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Dzip-like_N PF13815.6 KFQ91420.1 - 0.49 10.4 5.5 0.55 10.2 5.5 1.0 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal HAUS5 PF14817.6 KFQ91420.1 - 0.61 8.8 6.3 0.61 8.8 6.3 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 ABC_tran_Xtn PF12848.7 KFQ91420.1 - 0.91 9.6 9.1 1.4 9.0 9.1 1.4 1 1 0 1 1 1 0 ABC transporter DUF4140 PF13600.6 KFQ91420.1 - 1.1 9.8 4.0 1.1 9.7 4.0 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) IMD PF08397.11 KFQ91420.1 - 1.4 8.2 9.1 1.4 8.2 9.1 1.0 1 0 0 1 1 1 0 IRSp53/MIM homology domain DUF612 PF04747.12 KFQ91420.1 - 3.9 6.5 10.5 3.8 6.5 10.5 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF612 Atg14 PF10186.9 KFQ91420.1 - 4 6.4 8.6 4 6.4 8.6 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LCD1 PF09798.9 KFQ91420.1 - 4.5 5.7 9.2 4.1 5.8 9.2 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein DnaJ PF00226.31 KFQ91421.1 - 7.7e-17 61.2 1.3 7.7e-17 61.2 1.3 2.1 2 0 0 2 2 2 1 DnaJ domain DUF3089 PF11288.8 KFQ91421.1 - 0.16 11.5 1.2 0.26 10.8 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3089) 7tm_1 PF00001.21 KFQ91422.1 - 1.5e-41 142.4 29.3 2e-41 142.0 29.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4731 PF15875.5 KFQ91422.1 - 4.7 7.5 8.0 46 4.3 1.7 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4731) XK-related PF09815.9 KFQ91424.1 - 6.8e-75 252.2 11.4 7.7e-75 252.1 11.4 1.0 1 0 0 1 1 1 1 XK-related protein Metallophos PF00149.28 KFQ91425.1 - 9.8e-11 42.5 0.5 1.5e-10 41.9 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RPA_C PF08784.11 KFQ91426.1 - 2.1e-24 86.2 0.2 4.9e-24 85.0 0.1 1.6 1 1 1 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KFQ91426.1 - 0.00032 20.6 0.0 0.00054 19.9 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 KFQ91426.1 - 0.014 15.2 0.1 1.3 8.9 0.0 2.3 1 1 1 2 2 2 0 RecQ-mediated genome instability protein 2 TFA2_Winged_2 PF18121.1 KFQ91426.1 - 0.018 14.7 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 TFA2 Winged helix domain 2 LexA_DNA_bind PF01726.16 KFQ91426.1 - 0.019 14.7 0.0 0.047 13.5 0.0 1.7 1 0 0 1 1 1 0 LexA DNA binding domain Stn1 PF10451.9 KFQ91426.1 - 0.073 12.0 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Telomere regulation protein Stn1 CABIT PF12736.7 KFQ91427.1 - 2.8e-34 118.7 0.0 1.1e-22 80.7 0.0 3.7 3 1 0 3 3 3 3 Cell-cycle sustaining, positive selection, Syntaxin_2 PF14523.6 KFQ91428.1 - 2.3e-24 85.7 14.9 3.4e-24 85.1 8.6 2.3 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KFQ91428.1 - 5.7e-18 64.6 0.4 1.1e-17 63.7 0.4 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KFQ91428.1 - 6.9e-10 38.9 15.8 2.3e-09 37.2 15.8 1.9 1 1 0 1 1 1 1 Syntaxin Sortilin-Vps10 PF15902.5 KFQ91428.1 - 0.0085 14.9 0.2 0.011 14.6 0.2 1.1 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, YxiJ PF14176.6 KFQ91428.1 - 0.022 15.2 0.1 0.049 14.1 0.1 1.5 1 0 0 1 1 1 0 YxiJ-like protein ABC_tran_CTD PF16326.5 KFQ91428.1 - 0.97 9.7 19.3 0.62 10.4 1.6 4.1 2 2 2 4 4 4 0 ABC transporter C-terminal domain ATG16 PF08614.11 KFQ91428.1 - 1.4 9.1 16.2 0.78 9.9 2.9 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Synaptobrevin PF00957.21 KFQ91428.1 - 2.1 8.2 9.8 0.68 9.8 2.6 2.7 2 1 0 2 2 2 0 Synaptobrevin GAS PF13851.6 KFQ91428.1 - 8.2 5.7 20.0 6.4 6.1 3.8 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CITED PF04487.12 KFQ91429.1 - 1.8e-80 270.3 15.7 2.1e-80 270.1 15.7 1.0 1 0 0 1 1 1 1 CITED Med15 PF09606.10 KFQ91429.1 - 7.3 5.1 27.8 8.7 4.9 27.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CTP_synth_N PF06418.14 KFQ91430.1 - 1.3e-129 431.2 0.1 1.7e-129 430.8 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KFQ91430.1 - 6e-55 186.0 0.0 1.1e-54 185.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KFQ91430.1 - 1.9e-09 37.6 0.0 4e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 Transket_pyr PF02779.24 KFQ91430.1 - 0.016 14.9 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain CbiA PF01656.23 KFQ91430.1 - 0.029 14.4 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SLED PF12140.8 KFQ91431.1 - 3.7e-37 127.3 0.1 5.6e-37 126.7 0.1 1.3 1 0 0 1 1 1 1 SLED domain SAM_1 PF00536.30 KFQ91431.1 - 8.2e-17 61.4 0.1 1.6e-16 60.5 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RBR PF17208.3 KFQ91431.1 - 6.2e-11 42.8 16.5 1.9e-10 41.3 16.5 1.9 1 0 0 1 1 1 1 RNA binding Region SAM_2 PF07647.17 KFQ91431.1 - 1.9e-07 31.1 0.0 4.3e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFQ91431.1 - 0.00038 20.4 0.0 0.00066 19.6 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Endothelin PF00322.17 KFQ91432.1 - 2.1e-22 78.4 18.0 5.6e-21 73.8 7.2 2.2 2 0 0 2 2 2 2 Endothelin family Phage_fiber_2 PF03406.13 KFQ91433.1 - 0.085 12.4 0.2 0.15 11.7 0.2 1.3 1 0 0 1 1 1 0 Phage tail fibre repeat DUF3533 PF12051.8 KFQ91434.1 - 7.8 5.3 9.0 11 4.9 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Lipocalin PF00061.23 KFQ91435.1 - 1.9e-22 80.0 0.7 2.1e-22 79.9 0.7 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 KFQ91435.1 - 0.00019 21.4 0.3 0.00038 20.4 0.3 1.4 1 1 1 2 2 2 1 Lipocalin / cytosolic fatty-acid binding protein family Myosin_N PF02736.19 KFQ91435.1 - 0.034 14.0 4.5 0.14 12.0 0.9 2.8 2 1 1 3 3 3 0 Myosin N-terminal SH3-like domain S1 PF00575.23 KFQ91436.1 - 5.2e-07 29.9 0.1 5.2e-07 29.9 0.1 1.7 2 0 0 2 2 2 1 S1 RNA binding domain zf-CCHC_3 PF13917.6 KFQ91436.1 - 0.0034 17.3 1.0 0.0034 17.3 1.0 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 KFQ91436.1 - 0.011 15.8 4.6 0.022 14.8 4.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Rtf2 PF04641.12 KFQ91436.1 - 0.041 13.2 18.0 0.051 12.9 18.0 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger SR-25 PF10500.9 KFQ91436.1 - 0.13 11.9 30.3 0.24 11.0 30.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIF_alpha PF05793.12 KFQ91436.1 - 0.73 8.3 27.9 1.2 7.6 27.9 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3827 PF12877.7 KFQ91436.1 - 0.9 7.8 14.4 1.1 7.6 14.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF913 PF06025.12 KFQ91436.1 - 1.1 8.2 6.7 1.1 8.2 6.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Neur_chan_memb PF02932.16 KFQ91436.1 - 8.8 6.3 6.2 9.5 6.2 6.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region WD40 PF00400.32 KFQ91437.1 - 1.2e-41 139.9 5.4 3.8e-07 30.7 0.0 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ91437.1 - 2.2e-14 53.5 0.1 0.0015 18.8 0.0 4.8 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFQ91437.1 - 3.3e-06 27.1 0.2 0.0034 17.3 0.2 2.8 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KFQ91437.1 - 0.00022 19.9 0.1 0.26 9.7 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.8 KFQ91437.1 - 0.00074 18.3 5.8 2.1 6.9 0.0 4.1 1 1 3 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KFQ91437.1 - 0.0045 16.4 0.0 0.91 8.8 0.1 2.3 1 1 1 2 2 2 2 WD40-like domain NKAIN PF05640.14 KFQ91438.1 - 3.1e-80 268.3 7.4 3.4e-80 268.2 7.4 1.0 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein Syndecan PF01034.20 KFQ91439.1 - 3.7e-28 97.2 0.2 5.6e-28 96.6 0.2 1.3 1 0 0 1 1 1 1 Syndecan domain ECF_trnsprt PF12822.7 KFQ91439.1 - 0.021 14.9 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Sarcoglycan_2 PF05510.13 KFQ91439.1 - 0.041 12.7 0.0 0.48 9.1 0.0 2.0 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon Mtp PF03821.16 KFQ91440.1 - 4.6e-104 347.1 12.2 5.1e-104 346.9 12.2 1.0 1 0 0 1 1 1 1 Golgi 4-transmembrane spanning transporter DUF4728 PF15860.5 KFQ91440.1 - 3.9e-05 24.3 15.2 0.0052 17.4 7.6 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4728) DUF4870 PF09685.10 KFQ91440.1 - 0.16 12.1 8.6 3.1 8.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) DUF1475 PF07343.11 KFQ91440.1 - 0.3 10.9 5.3 0.26 11.1 2.7 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1475) CybS PF05328.12 KFQ91440.1 - 0.45 10.2 4.6 2.3 7.9 0.6 2.6 1 1 1 2 2 2 0 CybS, succinate dehydrogenase cytochrome B small subunit VWA PF00092.28 KFQ91441.1 - 4.9e-102 339.5 4.2 2.9e-53 180.7 0.6 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 KFQ91441.1 - 5.5e-38 129.9 0.2 1.7e-18 67.2 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain Matrilin_ccoil PF10393.9 KFQ91441.1 - 7.1e-11 41.8 0.5 1.9e-10 40.4 0.5 1.8 1 0 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin FXa_inhibition PF14670.6 KFQ91441.1 - 7.8e-10 38.9 13.5 2.3e-09 37.4 7.5 2.5 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFQ91441.1 - 5.2e-06 26.3 2.0 5.2e-06 26.3 2.0 2.2 3 0 0 3 3 3 1 Complement Clr-like EGF-like EGF_CA PF07645.15 KFQ91441.1 - 3.4e-05 23.9 6.1 3.4e-05 23.9 6.1 2.5 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF PF00008.27 KFQ91441.1 - 0.0095 16.2 3.9 0.035 14.4 3.9 2.0 1 0 0 1 1 1 1 EGF-like domain DUF2242 PF10001.9 KFQ91441.1 - 0.038 14.2 0.0 7.7 6.7 0.0 2.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2242) hEGF PF12661.7 KFQ91441.1 - 0.13 13.0 0.2 0.13 13.0 0.2 2.7 3 0 0 3 3 3 0 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 KFQ91441.1 - 4.5 7.7 12.4 0.05 13.9 4.3 1.9 2 0 0 2 2 2 0 Pvs28 EGF domain Aa_trans PF01490.18 KFQ91442.1 - 6.5e-83 278.7 33.3 1.4e-46 159.0 13.9 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein ECSCR PF15820.5 KFQ91442.1 - 3.1 7.7 6.2 0.55 10.1 0.1 2.9 3 0 0 3 3 3 0 Endothelial cell-specific chemotaxis regulator LRR_8 PF13855.6 KFQ91443.1 - 2.7e-24 84.7 12.4 2e-13 49.9 5.0 4.3 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KFQ91443.1 - 1.1e-12 47.9 17.9 9.3e-07 29.1 1.5 4.6 1 1 6 7 7 7 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFQ91443.1 - 2.9e-07 30.5 0.5 6.3e-07 29.4 0.5 1.5 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFQ91443.1 - 4.4e-07 29.6 17.2 0.063 13.8 0.2 7.4 7 1 0 7 7 6 2 Leucine Rich Repeat LRR_9 PF14580.6 KFQ91443.1 - 3.1e-06 26.8 0.7 1.2e-05 24.9 0.4 1.9 1 1 1 2 2 2 1 Leucine-rich repeat ig PF00047.25 KFQ91443.1 - 3.6e-06 27.1 0.0 8.8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFQ91443.1 - 7.3e-06 26.5 0.0 2e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ91443.1 - 0.0002 21.4 0.0 0.0004 20.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 KFQ91443.1 - 0.0003 20.9 0.0 0.0007 19.8 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin V-set domain LRR_6 PF13516.6 KFQ91443.1 - 0.0026 17.7 14.2 1.4 9.1 0.2 6.0 6 0 0 6 6 6 2 Leucine Rich repeat LRRNT PF01462.18 KFQ91443.1 - 0.0037 16.9 1.7 0.0037 16.9 1.7 3.3 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain Ig_2 PF13895.6 KFQ91443.1 - 0.014 15.8 0.0 0.032 14.6 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Herpes_gE PF02480.16 KFQ91443.1 - 0.05 12.4 0.0 4.1 6.0 0.0 2.1 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E Yae1_N PF09811.9 KFQ91444.1 - 2.6e-14 52.6 54.9 1.8e+04 -20.0 54.9 5.3 1 1 0 1 1 1 0 Essential protein Yae1, N terminal TPR_1 PF00515.28 KFQ91445.1 - 1e-33 113.8 23.7 4.6e-06 26.2 1.1 7.2 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ91445.1 - 1.9e-26 90.0 23.2 9.9e-05 22.2 0.1 6.7 6 0 0 6 6 6 6 Tetratricopeptide repeat RPAP3_C PF13877.6 KFQ91445.1 - 9.1e-26 90.2 2.2 1.4e-25 89.6 0.6 2.3 2 0 0 2 2 1 1 Potential Monad-binding region of RPAP3 TPR_8 PF13181.6 KFQ91445.1 - 1.5e-18 65.4 16.7 0.0022 18.1 0.4 7.3 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ91445.1 - 2.5e-16 59.0 13.8 0.00026 20.6 0.0 5.9 3 2 3 6 6 6 4 TPR repeat TPR_7 PF13176.6 KFQ91445.1 - 1.5e-14 52.8 5.1 0.00011 22.0 0.0 5.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ91445.1 - 9.7e-11 41.6 2.7 0.037 14.8 0.1 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ91445.1 - 2.5e-10 40.8 8.7 0.018 15.7 1.8 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFQ91445.1 - 4.5e-10 39.5 0.4 0.0023 18.0 0.2 4.3 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ91445.1 - 1.9e-09 37.7 14.0 0.38 11.1 0.0 5.3 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ91445.1 - 2.2e-08 34.5 9.3 0.018 15.6 1.1 4.7 2 2 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ91445.1 - 0.00022 21.0 10.9 11 6.0 0.2 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFQ91445.1 - 0.00035 21.0 9.9 9.7 7.1 0.6 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 KFQ91445.1 - 0.011 16.0 1.3 10 6.6 0.1 4.2 4 0 0 4 4 3 0 PPR repeat Fis1_TPR_C PF14853.6 KFQ91445.1 - 0.014 15.4 17.6 0.031 14.3 0.1 5.9 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Reprolysin_5 PF13688.6 KFQ91445.1 - 0.11 12.6 0.1 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 Metallo-peptidase family M12 RPN7 PF10602.9 KFQ91445.1 - 0.16 11.7 0.0 0.16 11.7 0.0 4.3 3 1 2 5 5 5 0 26S proteasome subunit RPN7 TPR_17 PF13431.6 KFQ91445.1 - 0.17 12.3 18.6 12 6.5 0.2 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat MIT PF04212.18 KFQ91445.1 - 0.21 11.7 10.4 7.4 6.7 0.1 4.5 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 KFQ91445.1 - 0.85 9.9 4.6 6.6 7.0 0.4 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR_2 PF13041.6 KFQ91445.1 - 3.4 8.0 4.5 28 5.0 0.1 3.3 4 0 0 4 4 2 0 PPR repeat family Spore_II_R PF09551.10 KFQ91445.1 - 9.5 6.7 9.0 0.59 10.6 0.8 3.0 2 1 1 3 3 3 0 Stage II sporulation protein R (spore_II_R) Peptidase_M76 PF09768.9 KFQ91446.1 - 1.5e-55 187.6 6.6 1.7e-55 187.4 6.6 1.0 1 0 0 1 1 1 1 Peptidase M76 family HypD PF01924.16 KFQ91446.1 - 0.0073 15.4 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase formation hypA family SprT-like PF10263.9 KFQ91446.1 - 0.024 14.5 0.9 0.039 13.8 0.9 1.4 1 0 0 1 1 1 0 SprT-like family Peptidase_M90 PF06167.12 KFQ91446.1 - 0.044 13.4 0.2 0.061 12.9 0.2 1.2 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 LRR_8 PF13855.6 KFQ91448.1 - 1.8e-86 283.8 81.9 9.7e-16 57.3 2.0 7.2 2 1 8 10 10 10 9 Leucine rich repeat I-set PF07679.16 KFQ91448.1 - 1.7e-49 165.8 0.0 1.8e-19 69.6 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ91448.1 - 3e-44 149.5 0.0 6.2e-14 52.4 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain LRR_4 PF12799.7 KFQ91448.1 - 2.3e-34 116.8 47.3 3e-06 27.5 0.4 9.2 4 2 5 10 10 10 9 Leucine Rich repeats (2 copies) Ig_2 PF13895.6 KFQ91448.1 - 8.4e-29 99.7 0.0 3e-08 33.9 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain LRR_5 PF13306.6 KFQ91448.1 - 1.9e-27 95.7 1.0 4.4e-11 42.8 0.1 3.4 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) ig PF00047.25 KFQ91448.1 - 3e-26 91.4 0.0 5.5e-07 29.7 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain LRR_9 PF14580.6 KFQ91448.1 - 1.3e-17 63.8 15.6 2e-05 24.2 3.0 5.0 1 1 4 5 5 5 5 Leucine-rich repeat V-set PF07686.17 KFQ91448.1 - 4.2e-12 46.2 2.6 0.08 13.1 0.1 5.7 3 3 1 4 4 4 3 Immunoglobulin V-set domain LRR_1 PF00560.33 KFQ91448.1 - 3.7e-11 42.0 31.4 0.63 10.8 1.0 12.4 12 1 0 12 12 12 3 Leucine Rich Repeat C2-set_2 PF08205.12 KFQ91448.1 - 6e-09 35.8 0.0 0.0015 18.5 0.0 3.7 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFQ91448.1 - 1.1e-08 34.5 0.0 0.11 12.1 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_5 PF16681.5 KFQ91448.1 - 2.6e-06 27.7 0.0 0.21 12.0 0.0 4.4 3 1 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFQ91448.1 - 4e-05 23.6 1.0 2.5 8.2 0.0 4.2 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain C1-set PF07654.15 KFQ91448.1 - 0.00074 19.8 0.0 0.029 14.7 0.0 3.0 3 0 0 3 3 3 1 Immunoglobulin C1-set domain LRR_6 PF13516.6 KFQ91448.1 - 0.0029 17.5 47.5 1.4 9.1 0.6 12.2 13 0 0 13 13 12 3 Leucine Rich repeat C2-set PF05790.15 KFQ91448.1 - 0.039 14.1 0.3 7.5 6.8 0.0 3.7 5 0 0 5 5 4 0 Immunoglobulin C2-set domain Receptor_2B4 PF11465.8 KFQ91448.1 - 0.046 13.9 0.0 1.7 8.9 0.0 2.7 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 MFS_1 PF07690.16 KFQ91452.1 - 9.3e-39 133.3 38.0 1.1e-34 120.0 28.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KFQ91452.1 - 8.8e-07 28.5 7.4 8.8e-07 28.5 7.4 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 KFQ91452.1 - 0.0021 17.0 8.9 0.0021 17.0 8.9 3.3 2 1 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 KFQ91452.1 - 0.0093 14.9 16.7 0.25 10.2 1.4 3.4 2 1 0 3 3 3 3 MFS_1 like family DUF2140 PF09911.9 KFQ91452.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF202 PF02656.15 KFQ91452.1 - 0.21 12.1 2.1 0.87 10.1 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Pardaxin PF07425.11 KFQ91452.1 - 1.5 8.5 4.9 0.27 10.9 0.6 2.1 2 0 0 2 2 2 0 Pardaxin RVT_1 PF00078.27 KFQ91453.1 - 0.0038 16.8 0.0 0.0059 16.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TAFA PF12020.8 KFQ91454.1 - 1.1e-32 112.3 9.0 1.5e-32 111.9 9.0 1.1 1 0 0 1 1 1 1 TAFA family PROCN PF08083.11 KFQ91455.1 - 5e-237 786.3 8.2 5e-237 786.3 8.2 1.6 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KFQ91455.1 - 2.3e-130 433.2 0.6 4e-130 432.4 0.6 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KFQ91455.1 - 9.7e-90 298.6 3.4 2.2e-89 297.5 3.4 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KFQ91455.1 - 3.9e-87 289.9 3.7 3.9e-87 289.9 3.7 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KFQ91455.1 - 4e-74 247.1 0.0 8e-74 246.1 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 KFQ91455.1 - 4.2e-54 181.7 0.0 1e-53 180.4 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 KFQ91455.1 - 2e-48 162.6 0.7 5.3e-48 161.3 0.7 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 KFQ91455.1 - 1.5e-13 50.7 0.0 4.2e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RILP PF11461.8 KFQ91457.1 - 1.5e-20 73.2 6.1 1.5e-20 73.2 6.1 2.8 3 2 0 3 3 3 1 Rab interacting lysosomal protein Jnk-SapK_ap_N PF09744.9 KFQ91457.1 - 0.00089 19.5 4.4 0.00089 19.5 4.4 3.1 3 0 0 3 3 3 2 JNK_SAPK-associated protein-1 Striatin PF08232.12 KFQ91457.1 - 0.02 15.5 6.7 0.02 15.5 6.7 2.3 2 1 1 3 3 3 0 Striatin family Leu_zip PF15294.6 KFQ91457.1 - 0.05 13.1 18.1 0.02 14.4 7.0 2.4 1 1 1 2 2 2 0 Leucine zipper DUF3584 PF12128.8 KFQ91457.1 - 0.44 8.0 19.8 0.035 11.6 5.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TMCO5 PF14992.6 KFQ91457.1 - 0.5 9.9 15.4 0.027 14.1 9.9 1.5 2 0 0 2 2 2 0 TMCO5 family Takusan PF04822.13 KFQ91457.1 - 4.7 7.2 18.4 0.15 11.9 1.4 3.3 2 1 1 3 3 3 0 Takusan DIRP PF06584.13 KFQ91457.1 - 5.3 7.3 10.4 0.11 12.7 0.8 2.6 2 1 1 3 3 3 0 DIRP Laminin_EGF PF00053.24 KFQ91458.1 - 5.8e-20 71.2 147.4 5.2e-05 23.3 5.9 10.1 5 3 5 10 10 10 9 Laminin EGF domain EGF_2 PF07974.13 KFQ91458.1 - 0.0004 20.7 7.8 0.0004 20.7 7.8 15.1 9 5 5 14 14 14 7 EGF-like domain IP_trans PF02121.18 KFQ91459.1 - 1.3e-113 378.6 1.4 1.7e-113 378.3 1.4 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein DUF5595 PF18077.1 KFQ91459.1 - 0.12 12.4 2.3 0.25 11.4 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) SKICH PF17751.1 KFQ91460.1 - 4e-30 104.4 0.1 7.3e-30 103.6 0.1 1.5 1 0 0 1 1 1 1 SKICH domain Exo_endo_phos PF03372.23 KFQ91460.1 - 8e-11 41.9 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Gal4_dimer PF03902.13 KFQ91460.1 - 0.015 15.4 0.2 0.075 13.2 0.1 2.2 2 0 0 2 2 2 0 Gal4-like dimerisation domain Myosin_head PF00063.21 KFQ91461.1 - 3.5e-252 838.5 5.4 4.6e-252 838.1 5.4 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KFQ91461.1 - 1.9e-32 112.5 1.6 4e-32 111.4 1.6 1.6 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding IQ PF00612.27 KFQ91461.1 - 9e-05 21.9 15.6 0.00044 19.8 0.7 4.0 4 0 0 4 4 4 2 IQ calmodulin-binding motif AAA_22 PF13401.6 KFQ91461.1 - 0.0043 17.3 0.0 0.065 13.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFQ91461.1 - 0.019 15.3 0.0 0.08 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 KFQ91461.1 - 0.026 13.8 0.0 0.059 12.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 KFQ91461.1 - 0.078 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE 14-3-3 PF00244.20 KFQ91462.1 - 9.4e-101 335.9 0.8 1e-100 335.8 0.8 1.0 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 KFQ91462.1 - 0.057 11.8 0.5 0.089 11.2 0.5 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 SH3_2 PF07653.17 KFQ91463.1 - 3.7e-25 87.4 0.4 1.7e-11 43.6 0.0 2.2 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KFQ91463.1 - 4.5e-19 67.8 0.5 2.2e-15 56.0 0.2 2.2 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KFQ91463.1 - 1.3e-13 50.5 0.1 2.6e-09 36.8 0.1 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_10 PF17902.1 KFQ91463.1 - 0.05 13.7 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 SH3 domain DUF3804 PF12707.7 KFQ91463.1 - 0.11 12.2 0.0 0.43 10.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3804) NCBP3 PF10309.9 KFQ91464.1 - 8.1e-21 73.6 0.1 2e-20 72.4 0.1 1.7 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 KFQ91464.1 - 0.0011 19.0 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 RNA binding domain NAD_binding_1 PF00175.21 KFQ91464.1 - 1.8 9.3 3.4 2.2 8.9 0.1 2.8 3 1 1 4 4 4 0 Oxidoreductase NAD-binding domain T2SSK PF03934.13 KFQ91465.1 - 0.00056 19.4 0.4 0.0029 17.0 0.1 1.9 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein K LRR_4 PF12799.7 KFQ91465.1 - 0.0017 18.7 1.0 0.0099 16.3 0.9 2.4 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFQ91465.1 - 0.076 13.1 0.7 0.45 10.7 0.2 2.5 2 0 0 2 2 2 0 Leucine Rich repeat TMEM219 PF14940.6 KFQ91466.1 - 2.9e-87 292.2 0.4 3.8e-87 291.8 0.4 1.1 1 0 0 1 1 1 1 Transmembrane 219 Omp28 PF11551.8 KFQ91466.1 - 0.043 13.6 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Outer membrane protein Omp28 VPS9 PF02204.18 KFQ91467.1 - 1.5e-29 102.2 0.0 5.1e-29 100.6 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KFQ91467.1 - 2.3e-21 75.9 1.6 7.2e-21 74.3 1.6 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) zf-A20 PF01754.16 KFQ91467.1 - 4.3e-12 45.7 6.8 9e-12 44.7 6.8 1.6 1 0 0 1 1 1 1 A20-like zinc finger Syntaxin PF00804.25 KFQ91467.1 - 0.039 13.6 12.1 0.54 9.9 4.5 2.6 2 1 1 3 3 3 0 Syntaxin SSTK-IP PF15836.5 KFQ91467.1 - 0.064 13.4 0.1 0.24 11.6 0.0 1.9 2 0 0 2 2 2 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein GIT1_C PF12205.8 KFQ91467.1 - 1.3 9.1 7.3 4.9 7.3 0.1 3.7 4 1 0 4 4 4 0 G protein-coupled receptor kinase-interacting protein 1 C term Mit_KHE1 PF10173.9 KFQ91467.1 - 5.3 7.1 7.5 2.8 8.0 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial K+-H+ exchange-related DUF2116 PF09889.9 KFQ91467.1 - 8.2 6.5 6.0 6.9 6.7 2.0 2.7 2 1 1 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) BTB_2 PF02214.22 KFQ91468.1 - 2.5e-20 72.6 0.1 1.4e-19 70.2 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 KFQ91468.1 - 0.0054 16.8 0.0 0.0091 16.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Sulfotransfer_3 PF13469.6 KFQ91469.1 - 2.5e-54 184.9 0.0 3.8e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KFQ91469.1 - 2.1e-08 34.0 0.1 2e-07 30.8 0.1 2.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 KFQ91469.1 - 0.0016 18.3 0.0 0.0083 16.0 0.1 2.2 1 1 1 2 2 2 1 Sulfotransferase domain RNA_pol_Rpb4 PF03874.16 KFQ91470.1 - 6.5e-10 39.4 0.3 7.9e-10 39.1 0.3 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 Lyase_1 PF00206.20 KFQ91471.1 - 2.4e-06 27.2 0.0 2.6e-06 27.1 0.0 1.0 1 0 0 1 1 1 1 Lyase Lyase_1 PF00206.20 KFQ91472.1 - 8.2e-107 357.2 0.0 3.1e-106 355.3 0.0 1.8 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.6 KFQ91472.1 - 1.7e-20 73.5 0.0 8.1e-20 71.4 0.0 2.3 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal Get5_bdg PF16843.5 KFQ91472.1 - 0.1 12.1 0.2 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein Glyco_hydro_2_C PF02836.17 KFQ91473.1 - 4.7e-106 354.3 0.0 5.9e-106 354.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KFQ91473.1 - 1.4e-17 64.2 0.0 2.6e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KFQ91473.1 - 3.1e-06 27.8 0.5 1.3e-05 25.8 0.5 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 VKOR PF07884.14 KFQ91474.1 - 1.1e-15 57.9 13.6 1.3e-15 57.7 13.6 1.1 1 0 0 1 1 1 1 Vitamin K epoxide reductase family G3P_acyltransf PF02660.15 KFQ91474.1 - 0.74 9.9 9.2 0.93 9.5 9.2 1.1 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase Tmemb_55A PF09788.9 KFQ91474.1 - 1.2 8.2 5.3 1.4 7.9 5.3 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A SPC25 PF06703.11 KFQ91474.1 - 6.6 6.5 11.9 6.8 6.5 10.7 1.6 1 1 1 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) CHCH PF06747.13 KFQ91475.1 - 1.6e-06 28.1 7.8 2.6e-06 27.4 7.8 1.4 1 0 0 1 1 1 1 CHCH domain Nup54_C PF18437.1 KFQ91475.1 - 0.2 11.6 0.1 0.41 10.6 0.1 1.5 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain Pkinase PF00069.25 KFQ91476.1 - 6.1e-78 261.8 0.0 7.5e-78 261.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ91476.1 - 8.6e-33 113.7 0.0 1.1e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ91476.1 - 1.1e-11 44.6 0.0 4.7e-10 39.2 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 KFQ91476.1 - 1.9e-07 30.7 0.1 3.5e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFQ91476.1 - 1.4e-05 24.1 0.1 0.00022 20.1 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 KFQ91476.1 - 2.1e-05 23.7 0.4 3.9e-05 22.8 0.4 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFQ91476.1 - 7.3e-05 22.8 0.3 0.31 10.9 0.2 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 KFQ91476.1 - 0.0001 22.0 1.0 0.00021 20.9 0.2 1.9 2 0 0 2 2 2 1 RIO1 family FTA2 PF13095.6 KFQ91476.1 - 0.0025 17.5 0.1 0.41 10.2 0.1 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 KFQ91476.1 - 0.0076 15.9 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Spc110_C PF18520.1 KFQ91476.1 - 0.026 14.1 0.3 0.2 11.3 0.1 2.2 2 0 0 2 2 2 0 Spindle pole body component 110 C-terminal domain YrbL-PhoP_reg PF10707.9 KFQ91476.1 - 0.13 11.8 0.1 0.25 10.9 0.1 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FGE-sulfatase PF03781.16 KFQ91477.1 - 3.2e-61 207.2 5.1 3.7e-61 207.0 5.1 1.0 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Cpn60_TCP1 PF00118.24 KFQ91478.1 - 2.2e-125 419.1 8.9 6.7e-69 232.8 0.1 2.0 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family Hydrolase PF00702.26 KFQ91479.1 - 8e-19 68.8 0.0 1.3e-18 68.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFQ91479.1 - 8e-13 49.2 0.0 1.4e-12 48.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFQ91479.1 - 1.9e-06 28.1 0.0 0.0036 17.4 0.0 2.6 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KFQ91479.1 - 3e-06 27.0 0.0 5.2e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.12 KFQ91479.1 - 3.7e-05 23.2 0.0 0.00014 21.3 0.0 1.8 2 1 0 2 2 2 1 Putative Phosphatase Acid_phosphat_B PF03767.14 KFQ91479.1 - 0.00071 19.2 0.0 0.042 13.4 0.0 2.1 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_3 PF08282.12 KFQ91479.1 - 0.012 15.4 0.0 0.45 10.2 0.0 2.5 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase StbA PF06406.11 KFQ91479.1 - 0.013 14.8 0.0 0.043 13.1 0.0 1.7 2 0 0 2 2 2 0 StbA protein Hydrolase_like PF13242.6 KFQ91479.1 - 0.053 13.6 0.0 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 HAD-hyrolase-like NIPSNAP PF07978.13 KFQ91480.1 - 1.5e-38 131.1 1.0 1.4e-32 111.9 0.2 2.2 2 0 0 2 2 2 2 NIPSNAP ERM PF00769.19 KFQ91481.1 - 1e-46 159.8 42.7 1e-46 159.8 42.7 2.2 2 0 0 2 2 2 1 Ezrin/radixin/moesin family FERM_M PF00373.18 KFQ91481.1 - 8.9e-27 93.8 1.3 8.9e-27 93.8 1.3 2.7 2 1 0 2 2 2 1 FERM central domain FERM_C PF09380.10 KFQ91481.1 - 3.6e-22 78.5 0.2 3.6e-22 78.5 0.2 2.6 3 0 0 3 3 3 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KFQ91481.1 - 6.3e-11 42.1 0.3 3.5e-10 39.7 0.3 2.3 1 0 0 1 1 1 1 FERM N-terminal domain Na_sulph_symp PF00939.19 KFQ91482.1 - 3.5e-119 398.9 25.7 4.7e-119 398.5 25.7 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KFQ91482.1 - 3.7e-35 121.6 30.7 9.5e-22 77.6 2.2 3.1 2 1 1 3 3 3 3 Citrate transporter DUF4713 PF15831.5 KFQ91482.1 - 5.4 7.5 15.5 9.2 6.8 0.0 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF4713) XAF1_C PF18608.1 KFQ91483.1 - 1.3e-17 63.1 0.9 1.3e-17 63.1 0.9 4.0 3 1 1 4 4 4 1 XIAP-associated factor 1 C-terminal domain zf_UBZ PF18439.1 KFQ91483.1 - 1.4e-06 27.7 29.8 0.022 14.3 0.1 6.4 6 0 0 6 6 6 5 Ubiquitin-Binding Zinc Finger PRP21_like_P PF12230.8 KFQ91483.1 - 0.017 15.0 14.5 1.6 8.5 0.1 3.6 2 1 1 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein DUF4723 PF15851.5 KFQ91483.1 - 3.3 7.9 11.7 0.47 10.6 0.7 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4723) WSC PF01822.19 KFQ91484.1 - 2.6e-31 107.6 19.5 5.2e-20 71.4 10.7 2.3 2 0 0 2 2 2 2 WSC domain Sulfotransfer_1 PF00685.27 KFQ91484.1 - 4.1e-08 33.0 0.2 8.5e-08 32.0 0.2 1.5 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFQ91484.1 - 0.0051 17.2 0.1 0.011 16.2 0.1 1.4 1 0 0 1 1 1 1 Sulfotransferase family PAN_1 PF00024.26 KFQ91484.1 - 2 8.4 8.6 9.8 6.2 0.7 3.2 2 1 1 3 3 3 0 PAN domain Rap_GAP PF02145.15 KFQ91485.1 - 8.4e-65 217.8 0.0 1.4e-64 217.1 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP CCDC92 PF14916.6 KFQ91486.1 - 9.1e-19 67.0 12.3 9.1e-19 67.0 12.3 2.2 2 1 0 2 2 2 1 Coiled-coil domain of unknown function Calici_MSP PF05752.11 KFQ91486.1 - 0.014 15.3 3.1 0.03 14.2 2.9 1.6 1 1 1 2 2 2 0 Calicivirus minor structural protein Rootletin PF15035.6 KFQ91486.1 - 0.086 12.9 17.0 0.83 9.6 2.9 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Cob_adeno_trans PF01923.18 KFQ91486.1 - 0.11 12.7 7.2 0.13 12.3 7.2 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase MYT1 PF08474.11 KFQ91486.1 - 0.12 12.3 0.7 0.14 12.1 0.7 1.1 1 0 0 1 1 1 0 Myelin transcription factor 1 Atg14 PF10186.9 KFQ91486.1 - 0.31 10.1 15.6 0.39 9.7 15.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPD52 PF04201.15 KFQ91486.1 - 0.67 9.5 17.4 0.14 11.8 8.2 2.2 1 1 1 2 2 2 0 Tumour protein D52 family FlxA PF14282.6 KFQ91486.1 - 0.69 9.9 13.0 2.5 8.2 5.0 2.2 1 1 1 2 2 2 0 FlxA-like protein Syntaphilin PF15290.6 KFQ91486.1 - 2 8.0 12.0 2.4 7.8 12.0 1.2 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Tox-ODYAM1 PF15642.6 KFQ91486.1 - 2.8 6.8 9.4 3 6.7 9.4 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus FlaC_arch PF05377.11 KFQ91486.1 - 4.7 7.7 8.0 15 6.1 1.3 3.1 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 KFQ91486.1 - 7 6.5 17.8 1.2 9.0 0.2 3.2 1 1 2 3 3 3 0 Septum formation initiator CLU PF13236.6 KFQ91487.1 - 8.1e-88 293.9 0.0 1.4e-87 293.2 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 KFQ91487.1 - 2.1e-60 203.8 0.0 5e-60 202.5 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 KFQ91487.1 - 4.5e-23 81.3 7.3 3.7e-10 39.9 0.3 3.8 1 1 1 3 3 3 3 Tetratricopeptide repeat CLU_N PF15044.6 KFQ91487.1 - 1.4e-15 57.4 1.2 3.3e-15 56.2 0.1 2.3 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 KFQ91487.1 - 5.9e-08 32.3 5.9 9.4e-05 22.1 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFQ91487.1 - 2e-06 27.4 3.3 6.5e-06 25.7 0.2 2.3 2 0 0 2 2 2 1 MalT-like TPR region DUF727 PF05303.12 KFQ91487.1 - 0.00025 21.1 0.0 0.00087 19.3 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF727) Rad60-SLD PF11976.8 KFQ91487.1 - 0.15 11.9 0.1 0.47 10.3 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like TPR_2 PF07719.17 KFQ91487.1 - 0.96 9.7 4.0 3.3 8.0 0.1 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ91487.1 - 3.4 7.9 6.0 4.3 7.6 0.2 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF1151 PF06625.11 KFQ91487.1 - 5 7.1 8.3 0.19 11.6 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) ANAPC_CDC26 PF10471.9 KFQ91487.1 - 5.5 7.9 6.7 12 6.8 2.2 3.0 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 WD40 PF00400.32 KFQ91488.1 - 8.3e-63 206.8 17.9 1.3e-08 35.3 0.6 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ91488.1 - 2.9e-16 59.5 2.7 0.047 14.0 0.0 5.8 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFQ91488.1 - 1.5e-12 47.0 11.3 0.01 14.5 0.0 6.4 2 2 4 7 7 7 4 Nucleoporin Nup120/160 LisH PF08513.11 KFQ91488.1 - 6.5e-09 35.4 0.4 1.6e-08 34.2 0.4 1.7 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 KFQ91488.1 - 3.3e-05 23.9 2.6 0.097 12.5 0.1 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 KFQ91488.1 - 4.8e-05 22.3 1.4 0.21 10.3 0.0 4.0 1 1 4 5 5 5 1 Nup133 N terminal like Ge1_WD40 PF16529.5 KFQ91488.1 - 0.00035 19.6 8.7 1.3 7.9 0.2 5.1 1 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Pox_A_type_inc PF04508.12 KFQ91488.1 - 0.0016 18.2 0.1 0.0037 17.0 0.1 1.6 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat LisH_2 PF16045.5 KFQ91488.1 - 0.018 14.1 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 LisH Roc PF08477.13 KFQ91488.1 - 0.055 13.7 0.8 1.7 8.9 0.0 3.0 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PH_RBD PF12068.8 KFQ91489.1 - 5.6e-36 123.5 0.5 6.1e-33 113.7 0.0 3.2 2 1 0 2 2 2 2 Rab-binding domain (RBD) RabGAP-TBC PF00566.18 KFQ91489.1 - 1e-31 110.3 10.5 7.1e-30 104.3 6.2 2.6 2 0 0 2 2 2 2 Rab-GTPase-TBC domain RUN PF02759.19 KFQ91489.1 - 2.2e-31 108.6 0.0 6.3e-31 107.1 0.0 1.9 1 0 0 1 1 1 1 RUN domain zf-BED PF02892.15 KFQ91489.1 - 0.0039 17.2 0.9 0.0093 16.0 0.1 2.1 2 0 0 2 2 2 1 BED zinc finger BTB_2 PF02214.22 KFQ91490.1 - 2.6e-20 72.6 0.0 4.9e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KFQ91490.1 - 4.7e-06 26.8 0.0 1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KFQ91490.1 - 0.015 15.4 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain IFT20 PF14931.6 KFQ91491.1 - 2e-32 111.8 8.8 2.2e-32 111.7 8.8 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 HRDC PF00570.23 KFQ91491.1 - 0.028 14.4 1.0 0.038 14.0 1.0 1.2 1 0 0 1 1 1 0 HRDC domain DUF737 PF05300.11 KFQ91491.1 - 0.34 11.3 5.1 0.38 11.1 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DUF2781 PF10914.8 KFQ91492.1 - 1.4e-20 74.2 2.2 1.5e-20 74.1 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Pkinase PF00069.25 KFQ91493.1 - 4.5e-59 200.0 0.0 7.7e-59 199.2 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ91493.1 - 3.5e-28 98.6 0.0 5.3e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFQ91493.1 - 0.00011 21.1 0.0 0.00017 20.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFQ91493.1 - 0.00076 18.5 0.2 0.0016 17.5 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KFQ91493.1 - 0.0083 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFQ91493.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 KFQ91493.1 - 0.032 13.9 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Complex1_LYR PF05347.15 KFQ91494.1 - 3.1e-16 59.2 0.9 3.4e-16 59.0 0.9 1.0 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFQ91494.1 - 8.7e-05 23.2 0.9 0.0001 23.0 0.9 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KFQ91494.1 - 0.0017 18.9 0.0 0.0018 18.8 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Sigma70_r4 PF04545.16 KFQ91494.1 - 0.029 13.9 0.5 6.8 6.3 0.0 2.3 2 1 0 2 2 2 0 Sigma-70, region 4 DUF1320 PF07030.12 KFQ91494.1 - 0.04 14.0 2.5 0.97 9.6 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1320) NO_synthase PF02898.15 KFQ91495.1 - 2e-186 619.3 0.0 2.9e-186 618.8 0.0 1.2 1 0 0 1 1 1 1 Nitric oxide synthase, oxygenase domain FAD_binding_1 PF00667.20 KFQ91495.1 - 8.5e-68 228.2 0.0 1.4e-67 227.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFQ91495.1 - 3.2e-41 140.9 0.0 7.8e-41 139.6 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KFQ91495.1 - 2.5e-22 79.6 0.1 8.1e-22 77.9 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KFQ91495.1 - 0.03 14.5 0.0 0.17 12.0 0.0 2.1 1 1 1 2 2 2 0 Ferric reductase NAD binding domain DUF1400 PF07176.11 KFQ91495.1 - 0.33 11.2 2.2 0.63 10.3 0.0 2.6 4 0 0 4 4 4 0 Alpha/beta hydrolase of unknown function (DUF1400) Pkinase_Tyr PF07714.17 KFQ91496.1 - 8.3e-48 162.9 0.0 1.4e-47 162.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ91496.1 - 3.4e-39 134.8 0.0 5.3e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SAM_KSR1 PF13543.6 KFQ91496.1 - 4.2e-17 62.5 0.1 8e-17 61.6 0.1 1.5 1 0 0 1 1 1 1 SAM like domain present in kinase suppressor RAS 1 Kinase-like PF14531.6 KFQ91496.1 - 9.3e-05 21.9 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like C1_1 PF00130.22 KFQ91496.1 - 0.00075 19.3 11.5 0.00075 19.3 11.5 1.9 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RIO1 PF01163.22 KFQ91496.1 - 0.003 17.2 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family zf-RING-like PF08746.11 KFQ91496.1 - 0.016 15.5 8.1 0.042 14.2 8.1 1.7 1 0 0 1 1 1 0 RING-like domain APH PF01636.23 KFQ91496.1 - 0.084 12.8 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KFQ91496.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAM76 PF16046.5 KFQ91496.1 - 0.69 9.2 8.3 1.6 8.0 8.3 1.6 1 0 0 1 1 1 0 FAM76 protein C1_2 PF03107.16 KFQ91496.1 - 1.1 9.6 7.0 3.9 7.9 7.0 1.9 1 0 0 1 1 1 0 C1 domain WD40 PF00400.32 KFQ91497.1 - 7.4e-35 118.4 14.2 6.4e-08 33.1 0.0 7.3 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ91497.1 - 5.4e-12 45.9 0.3 0.015 15.5 0.0 5.6 3 2 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFQ91497.1 - 1.5e-09 37.3 0.3 0.066 12.2 0.0 4.4 2 2 1 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein SOCS_box PF07525.16 KFQ91497.1 - 3e-09 37.1 0.2 5.8e-09 36.2 0.2 1.5 1 0 0 1 1 1 1 SOCS box eIF2A PF08662.11 KFQ91497.1 - 8.8e-06 25.7 0.0 0.046 13.6 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KFQ91497.1 - 0.00046 19.6 0.0 2.3 7.5 0.0 3.2 1 1 2 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KFQ91497.1 - 0.0027 16.4 0.4 0.15 10.7 0.1 2.5 1 1 1 2 2 2 1 Nucleoporin Nup120/160 PD40 PF07676.12 KFQ91497.1 - 0.028 14.4 6.7 11 6.1 0.2 5.0 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KFQ91497.1 - 0.047 12.2 0.2 3.8 5.9 0.0 2.1 1 1 1 2 2 2 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 KFQ91497.1 - 0.21 12.1 1.6 54 4.5 0.1 3.9 4 0 0 4 4 4 0 PQQ-like domain RasGAP PF00616.19 KFQ91498.1 - 7.9e-29 100.9 0.2 4.8e-20 72.2 0.1 3.0 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 KFQ91498.1 - 1.4e-22 80.3 0.0 5.9e-22 78.3 0.0 2.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KFQ91498.1 - 0.0052 16.5 0.0 0.072 12.8 0.0 2.8 2 0 0 2 2 2 1 CRAL/TRIO domain MOR2-PAG1_C PF14225.6 KFQ91498.1 - 0.023 14.6 4.1 0.027 14.4 0.1 3.4 3 0 0 3 3 3 0 Cell morphogenesis C-terminal MIF4G_like_2 PF09090.11 KFQ91498.1 - 0.091 12.2 1.9 0.26 10.7 0.2 2.6 3 0 0 3 3 3 0 MIF4G like LRR_8 PF13855.6 KFQ91499.1 - 4.3e-15 55.2 24.4 2.6e-09 36.7 1.3 4.1 2 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFQ91499.1 - 8.6e-15 54.6 29.7 0.00018 21.8 2.3 5.4 3 2 1 5 5 5 5 Leucine Rich repeats (2 copies) LRRNT PF01462.18 KFQ91499.1 - 3e-08 33.1 2.9 7e-08 31.9 2.9 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KFQ91499.1 - 1.2e-07 31.2 18.5 0.68 10.7 0.2 7.0 6 1 1 7 7 7 4 Leucine Rich Repeat LRR_9 PF14580.6 KFQ91499.1 - 0.025 14.1 8.1 0.31 10.5 1.3 2.3 1 1 1 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 KFQ91499.1 - 0.31 11.2 23.6 3.6 7.9 0.7 6.2 6 0 0 6 6 6 0 Leucine Rich repeat EVI2A PF05399.11 KFQ91500.1 - 2.7e-79 266.0 10.0 3.3e-79 265.7 10.0 1.1 1 0 0 1 1 1 1 Ectropic viral integration site 2A protein (EVI2A) TMEM154 PF15102.6 KFQ91500.1 - 0.013 15.4 6.2 0.013 15.4 6.2 2.2 2 1 0 2 2 2 0 TMEM154 protein family C_Hendra PF16821.5 KFQ91500.1 - 0.065 13.1 0.5 0.065 13.1 0.5 1.8 2 0 0 2 2 2 0 C protein from hendra and measles viruses Lipocalin_4 PF13648.6 KFQ91500.1 - 0.07 14.1 4.0 0.2 12.6 4.0 1.8 1 0 0 1 1 1 0 Lipocalin-like domain Baculo_11_kDa PF06143.11 KFQ91500.1 - 0.078 12.6 0.2 0.21 11.2 0.2 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family MFS_2 PF13347.6 KFQ91500.1 - 0.085 11.4 0.1 0.1 11.1 0.1 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein RIFIN PF02009.16 KFQ91500.1 - 0.15 12.0 4.2 0.05 13.5 1.0 1.7 2 0 0 2 2 2 0 Rifin Tmemb_9 PF05434.11 KFQ91500.1 - 0.23 11.4 3.5 0.44 10.4 0.0 2.6 3 0 0 3 3 3 0 TMEM9 EphA2_TM PF14575.6 KFQ91500.1 - 0.31 12.0 1.7 1.5 9.7 1.7 2.2 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 KFQ91500.1 - 0.43 10.9 3.1 0.72 10.2 0.3 2.5 2 1 0 2 2 2 0 Orf78 (ac78) Miga PF10265.9 KFQ91500.1 - 6.2 5.7 8.1 11 4.8 5.2 2.0 2 0 0 2 2 2 0 Mitoguardin TUDOR PF00567.24 KFQ91501.1 - 1.5e-17 63.8 0.0 4.4e-17 62.2 0.0 1.9 1 1 0 1 1 1 1 Tudor domain KH_1 PF00013.29 KFQ91501.1 - 8.7e-11 41.5 0.0 2.2e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 KFQ91501.1 - 0.031 14.2 0.0 0.091 12.6 0.0 1.7 1 0 0 1 1 1 0 KH domain Agenet PF05641.12 KFQ91501.1 - 0.056 13.9 0.0 0.19 12.2 0.0 1.9 1 0 0 1 1 1 0 Agenet domain RII_binding_1 PF10522.9 KFQ91501.1 - 0.32 11.3 2.0 1 9.8 2.0 1.9 1 0 0 1 1 1 0 RII binding domain RRM_1 PF00076.22 KFQ91502.1 - 0.27 11.1 0.7 0.39 10.6 0.1 1.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MRP-S23 PF10484.9 KFQ91503.1 - 9.6e-12 45.3 0.1 1e-11 45.2 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S23 CUE PF02845.16 KFQ91504.1 - 1.5e-15 56.5 0.2 3.4e-15 55.4 0.2 1.6 1 0 0 1 1 1 1 CUE domain zf-C2H2 PF00096.26 KFQ91505.1 - 1.2e-16 60.2 56.2 0.0024 18.2 2.8 6.9 7 0 0 7 7 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ91505.1 - 1.3e-16 59.8 55.0 0.00039 21.0 1.0 6.9 7 0 0 7 7 6 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFQ91505.1 - 1.1e-12 47.8 58.8 5e-06 26.7 2.6 8.7 9 0 0 9 9 8 4 Zinc-finger double domain Spt20 PF12090.8 KFQ91505.1 - 0.00014 21.6 32.7 0.00035 20.3 32.7 1.7 1 0 0 1 1 1 1 Spt20 family zf-C2H2_jaz PF12171.8 KFQ91505.1 - 0.00015 22.0 23.5 0.19 12.1 0.7 6.4 6 0 0 6 6 5 1 Zinc-finger double-stranded RNA-binding EIF4E-T PF10477.9 KFQ91505.1 - 0.008 15.1 18.0 0.0097 14.8 18.0 1.1 1 0 0 1 1 1 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E zf-C2H2_6 PF13912.6 KFQ91505.1 - 0.0085 16.1 0.4 0.0085 16.1 0.4 7.6 9 0 0 9 9 6 4 C2H2-type zinc finger Suf PF05843.14 KFQ91505.1 - 0.014 15.4 11.8 0.029 14.4 11.8 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) EOS1 PF12326.8 KFQ91505.1 - 0.015 15.3 8.8 0.035 14.0 8.8 1.6 1 0 0 1 1 1 0 N-glycosylation protein DDHD PF02862.17 KFQ91505.1 - 0.015 15.5 10.9 0.022 14.9 8.9 2.1 2 0 0 2 2 2 0 DDHD domain DUF5427 PF10310.9 KFQ91505.1 - 0.019 13.9 14.6 0.029 13.3 14.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) zf-Di19 PF05605.12 KFQ91505.1 - 0.021 15.1 33.7 0.43 10.9 3.2 4.6 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding CPSF100_C PF13299.6 KFQ91505.1 - 0.024 14.8 10.3 0.14 12.3 10.5 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal zf-BED PF02892.15 KFQ91505.1 - 0.031 14.3 2.7 0.031 14.3 2.7 6.8 5 2 2 7 7 7 0 BED zinc finger ABC2_membrane_2 PF12679.7 KFQ91505.1 - 0.056 12.7 0.4 0.1 11.9 0.4 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein PAT1 PF09770.9 KFQ91505.1 - 0.079 11.2 24.0 0.12 10.7 24.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.12 KFQ91505.1 - 0.11 11.5 17.4 0.15 11.0 17.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) zf_C2H2_13 PF18508.1 KFQ91505.1 - 0.13 11.9 0.1 0.13 11.9 0.1 3.2 3 0 0 3 3 2 0 Zinc finger domain Exonuc_VII_L PF02601.15 KFQ91505.1 - 0.18 11.4 13.2 0.28 10.7 13.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4192 PF13830.6 KFQ91505.1 - 0.2 11.7 1.6 0.3 11.1 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) CSG2 PF16965.5 KFQ91505.1 - 0.24 10.3 5.5 0.37 9.7 5.5 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator ALMT PF11744.8 KFQ91505.1 - 0.24 10.2 13.2 0.39 9.5 13.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 KFQ91505.1 - 0.27 10.2 13.3 0.4 9.7 13.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 KFQ91505.1 - 0.32 9.1 11.4 0.44 8.6 11.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EMC3_TMCO1 PF01956.16 KFQ91505.1 - 0.34 10.6 7.8 0.66 9.7 7.8 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Band_3_cyto PF07565.13 KFQ91505.1 - 0.4 10.4 11.9 0.86 9.4 11.9 1.6 1 0 0 1 1 1 0 Band 3 cytoplasmic domain AUX_IAA PF02309.16 KFQ91505.1 - 0.41 10.5 9.3 0.89 9.4 9.3 1.5 1 0 0 1 1 1 0 AUX/IAA family Pinin_SDK_memA PF04696.13 KFQ91505.1 - 0.42 10.7 26.5 0.79 9.8 26.5 1.3 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Folate_carrier PF01770.18 KFQ91505.1 - 0.47 9.1 5.8 0.7 8.6 5.8 1.2 1 0 0 1 1 1 0 Reduced folate carrier RR_TM4-6 PF06459.12 KFQ91505.1 - 0.53 10.1 15.3 0.42 10.4 13.3 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SUFU_C PF12470.8 KFQ91505.1 - 0.57 10.2 10.7 1.2 9.2 10.7 1.4 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain CobT PF06213.12 KFQ91505.1 - 0.6 9.4 20.1 1.1 8.6 20.1 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Tim54 PF11711.8 KFQ91505.1 - 0.66 8.7 10.5 1.1 8.0 10.5 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 EPL1 PF10513.9 KFQ91505.1 - 0.69 10.3 16.2 0.019 15.3 9.0 2.1 3 0 0 3 3 1 0 Enhancer of polycomb-like Zip PF02535.22 KFQ91505.1 - 0.73 9.0 7.8 1.5 8.0 7.8 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter SpoIIP PF07454.11 KFQ91505.1 - 0.73 9.2 15.3 1.1 8.6 15.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Paramyxo_ncap PF00973.19 KFQ91505.1 - 0.89 8.4 13.6 1.4 7.8 13.6 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Presenilin PF01080.17 KFQ91505.1 - 1.1 8.0 18.2 1.7 7.3 18.2 1.3 1 0 0 1 1 1 0 Presenilin AIF_C PF14721.6 KFQ91505.1 - 1.2 9.5 9.9 2.9 8.3 9.9 1.7 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3537 PF12056.8 KFQ91505.1 - 1.3 7.8 9.5 2.4 6.9 9.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) zf-C2H2_2 PF12756.7 KFQ91505.1 - 1.4 9.3 0.0 1.4 9.3 0.0 6.6 2 1 3 6 6 5 0 C2H2 type zinc-finger (2 copies) DUF4407 PF14362.6 KFQ91505.1 - 1.8 7.8 15.5 2.7 7.3 15.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4834 PF16118.5 KFQ91505.1 - 1.9 9.5 17.3 5.5 8.0 17.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) zf-C2H2_8 PF15909.5 KFQ91505.1 - 2.3 8.6 17.1 0.32 11.3 3.4 3.6 2 1 1 3 3 3 0 C2H2-type zinc ribbon Coilin_N PF15862.5 KFQ91505.1 - 2.4 8.0 19.0 5.9 6.7 19.0 1.6 1 0 0 1 1 1 0 Coilin N-terminus zf_C2H2_ZHX PF18387.1 KFQ91505.1 - 2.6 7.8 14.3 2.6 7.8 0.4 3.8 2 1 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain XRN_M PF17846.1 KFQ91505.1 - 3.2 6.6 12.6 5 6.0 12.6 1.2 1 0 0 1 1 1 0 Xrn1 helical domain EIIBC-GUT_N PF03612.14 KFQ91505.1 - 3.4 7.4 13.2 6.7 6.4 13.2 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Peptidase_S49_N PF08496.10 KFQ91505.1 - 3.5 7.7 11.8 7.6 6.6 11.8 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PepSY_TM PF03929.16 KFQ91505.1 - 3.6 7.2 6.7 6.7 6.3 6.7 1.4 1 0 0 1 1 1 0 PepSY-associated TM region Membralin PF09746.9 KFQ91505.1 - 3.7 6.5 9.8 5.2 6.0 9.8 1.2 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 KFQ91505.1 - 4 7.4 21.6 7.1 6.6 21.6 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 ThiD2 PF17792.1 KFQ91505.1 - 4.3 7.8 8.1 9.3 6.7 8.1 1.5 1 0 0 1 1 1 0 ThiD2 family Ctr PF04145.15 KFQ91505.1 - 4.7 7.8 8.3 12 6.5 8.3 1.7 1 0 0 1 1 1 0 Ctr copper transporter family V_ATPase_I PF01496.19 KFQ91505.1 - 4.9 4.9 14.4 6.7 4.5 14.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4820 PF16091.5 KFQ91505.1 - 5.6 6.3 14.8 0.94 8.8 9.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) WES_acyltransf PF03007.16 KFQ91505.1 - 5.6 6.6 11.2 5.3 6.7 7.1 2.3 2 0 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Serinc PF03348.15 KFQ91505.1 - 6.3 5.6 12.4 1.3 7.8 7.3 1.9 2 0 0 2 2 2 0 Serine incorporator (Serinc) zf-CHCC PF10276.9 KFQ91505.1 - 6.4 6.9 14.4 45 4.2 0.1 5.6 6 0 0 6 6 5 0 Zinc-finger domain DUF4175 PF13779.6 KFQ91505.1 - 6.5 4.5 33.4 8.9 4.1 33.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) zf-FCS PF06467.14 KFQ91505.1 - 7.1 6.7 29.8 2 8.4 3.0 6.6 5 2 2 7 7 7 0 MYM-type Zinc finger with FCS sequence motif DUF4746 PF15928.5 KFQ91505.1 - 7.4 5.9 11.7 12 5.2 11.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) MMR1 PF08505.10 KFQ91505.1 - 7.4 6.8 28.0 8 6.7 22.5 2.3 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein CCDC53 PF10152.9 KFQ91505.1 - 7.9 6.9 18.5 0.21 12.0 11.0 2.1 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF1980 PF09323.10 KFQ91505.1 - 8.2 6.3 13.2 19 5.1 13.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF2722 PF10846.8 KFQ91505.1 - 8.4 5.2 43.3 0.65 8.9 38.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) FAM176 PF14851.6 KFQ91505.1 - 9.9 5.8 12.2 19 4.9 12.2 1.4 1 0 0 1 1 1 0 FAM176 family Dynein_light PF01221.18 KFQ91506.1 - 5.2e-44 148.5 2.1 5.8e-44 148.3 2.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Nop PF01798.18 KFQ91506.1 - 0.067 12.7 0.0 0.074 12.5 0.0 1.0 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin Ectatomin PF06457.11 KFQ91506.1 - 0.15 12.0 0.2 0.25 11.3 0.2 1.4 1 0 0 1 1 1 0 Ectatomin DUF4042 PF13251.6 KFQ91507.1 - 1.7e-71 239.7 5.0 4.2e-70 235.2 0.1 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF4042) HEAT_2 PF13646.6 KFQ91507.1 - 1.4e-21 76.7 1.4 3.7e-06 27.2 0.0 6.7 5 3 1 6 6 6 4 HEAT repeats HEAT PF02985.22 KFQ91507.1 - 3.7e-20 70.3 11.8 0.00018 21.5 0.0 9.8 9 0 0 9 9 9 5 HEAT repeat HEAT_EZ PF13513.6 KFQ91507.1 - 1.3e-13 51.1 20.7 2.6e-06 27.8 0.8 9.3 8 3 4 12 12 11 4 HEAT-like repeat Adaptin_N PF01602.20 KFQ91507.1 - 1.5e-05 23.8 5.1 0.56 8.7 0.1 4.4 4 0 0 4 4 4 3 Adaptin N terminal region Cnd1 PF12717.7 KFQ91507.1 - 1.5e-05 25.1 6.8 0.22 11.6 0.1 4.6 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 MMS19_N PF14500.6 KFQ91507.1 - 0.015 14.9 2.6 0.23 11.0 0.2 3.8 3 2 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II API5 PF05918.11 KFQ91507.1 - 0.02 13.7 3.6 2.2 7.0 0.0 4.0 3 1 1 4 4 4 0 Apoptosis inhibitory protein 5 (API5) HEAT_PBS PF03130.16 KFQ91507.1 - 0.029 15.0 8.8 3.9 8.4 0.0 6.3 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat FANCI_S2 PF14676.6 KFQ91507.1 - 0.11 12.7 4.9 3.4 7.9 0.1 3.4 3 0 0 3 3 3 0 FANCI solenoid 2 Arm PF00514.23 KFQ91507.1 - 0.2 11.7 27.2 1.8 8.7 0.2 8.2 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat RasGEF_N_2 PF14663.6 KFQ91507.1 - 0.32 11.4 5.4 11 6.5 0.1 3.5 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HNF-1B_C PF04812.13 KFQ91508.1 - 1.3e-120 401.6 40.4 2.1e-120 401.0 40.4 1.3 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus HNF-1_N PF04814.13 KFQ91508.1 - 1.8e-62 211.5 0.0 1.8e-62 211.5 0.0 3.0 4 0 0 4 4 4 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Homeodomain PF00046.29 KFQ91508.1 - 3.1e-05 23.7 1.2 0.00026 20.8 1.2 2.5 1 1 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ91508.1 - 0.035 14.0 0.0 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 Homeobox KN domain HTH_5 PF01022.20 KFQ91508.1 - 1.3 8.9 3.3 1 9.3 0.1 2.4 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family DEAD PF00270.29 KFQ91509.1 - 4.5e-38 130.7 0.0 8e-38 130.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFQ91509.1 - 7.1e-31 106.8 0.1 1.2e-28 99.7 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFQ91509.1 - 2.8e-06 27.4 0.8 6e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KFQ91509.1 - 0.0017 18.7 0.0 0.004 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain HEM4 PF02602.15 KFQ91509.1 - 0.046 13.1 0.1 0.096 12.0 0.1 1.5 1 1 0 1 1 1 0 Uroporphyrinogen-III synthase HemD EF-hand_4 PF12763.7 KFQ91510.1 - 0.024 14.6 0.0 0.068 13.1 0.0 1.8 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Myb_DNA-binding PF00249.31 KFQ91511.1 - 2.6e-10 40.3 0.1 6.5e-10 39.1 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 KFQ91511.1 - 3.6e-08 33.6 0.0 1.8e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 KFQ91511.1 - 4.7e-06 26.8 0.3 5.3e-05 23.4 0.1 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Spatacsin_C PF14649.6 KFQ91511.1 - 0.11 11.6 0.5 0.19 10.8 0.5 1.3 1 0 0 1 1 1 0 Spatacsin C-terminus RNA_pol_Rpb4 PF03874.16 KFQ91511.1 - 0.29 11.5 2.7 0.76 10.1 1.2 2.4 2 1 0 2 2 2 0 RNA polymerase Rpb4 DUF4711 PF15829.5 KFQ91512.1 - 3.6e-56 190.6 1.5 4.2e-56 190.4 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4711) DUF5097 PF17020.5 KFQ91512.1 - 0.048 14.0 0.1 0.1 13.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5097) SpoU_methylase PF00588.19 KFQ91513.1 - 4.2e-31 108.0 0.0 5.8e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KFQ91513.1 - 2.4e-13 50.1 0.0 3.9e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding adh_short PF00106.25 KFQ91514.1 - 3.7e-32 111.4 0.0 4.4e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFQ91514.1 - 6e-30 104.5 0.0 7e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFQ91514.1 - 0.0066 16.4 0.0 0.0089 16.0 0.0 1.3 1 1 0 1 1 1 1 KR domain AP3D1 PF06375.11 KFQ91515.1 - 0.32 11.2 11.4 0.65 10.2 1.3 2.7 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 GWT1 PF06423.12 KFQ91516.1 - 5.6e-35 120.7 1.9 5.6e-35 120.7 1.9 2.8 4 0 0 4 4 4 1 GWT1 Tmemb_55A PF09788.9 KFQ91516.1 - 0.24 10.5 1.8 0.26 10.4 0.1 1.9 2 0 0 2 2 2 0 Transmembrane protein 55A Myosin_head PF00063.21 KFQ91517.1 - 1.2e-201 671.5 1.7 1.6e-201 671.1 1.7 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 KFQ91517.1 - 0.00025 20.6 12.7 0.0019 17.8 1.0 3.2 3 0 0 3 3 3 2 IQ calmodulin-binding motif AAA_22 PF13401.6 KFQ91517.1 - 0.0012 19.2 0.0 0.013 15.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFQ91517.1 - 0.012 16.0 0.3 0.47 10.8 0.0 3.4 4 0 0 4 4 4 0 AAA ATPase domain Microtub_bd PF16796.5 KFQ91517.1 - 0.046 13.7 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Microtubule binding ParcG PF10274.9 KFQ91518.1 - 0.0035 17.5 0.0 0.0038 17.4 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein 7tm_1 PF00001.21 KFQ91519.1 - 2.2e-26 92.8 19.4 2.5e-26 92.6 19.4 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2418 PF10332.9 KFQ91519.1 - 0.75 10.4 6.4 0.24 12.0 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) Carb_anhydrase PF00194.21 KFQ91520.1 - 7e-93 310.8 1.0 7.9e-93 310.6 1.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase UCH PF00443.29 KFQ91521.1 - 4.9e-85 285.1 0.1 8.1e-85 284.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KFQ91521.1 - 3.5e-26 91.7 0.0 1.9e-25 89.3 0.0 2.4 1 1 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 KFQ91521.1 - 1.1e-14 54.8 0.0 6.9e-08 32.4 0.0 3.4 2 2 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase EF-hand_6 PF13405.6 KFQ91521.1 - 4.2e-10 38.7 1.7 0.0016 18.3 0.0 4.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KFQ91521.1 - 8.4e-10 37.5 1.7 8e-05 21.9 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KFQ91521.1 - 1.3e-09 38.3 2.1 4.9e-07 30.1 0.5 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KFQ91521.1 - 6.1e-09 35.0 3.4 4.9e-05 22.6 0.1 2.7 2 0 0 2 2 2 2 EF hand Ubiquitin_3 PF14836.6 KFQ91521.1 - 1.3e-05 25.1 0.2 3.4e-05 23.7 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_2 PF14560.6 KFQ91521.1 - 5.3e-05 23.6 1.3 0.003 18.0 0.3 3.0 2 0 0 2 2 2 1 Ubiquitin-like domain EF-hand_8 PF13833.6 KFQ91521.1 - 0.00034 20.4 6.2 0.25 11.2 0.3 3.4 2 1 1 3 3 3 3 EF-hand domain pair DUF4208 PF13907.6 KFQ91522.1 - 7.1e-20 71.2 1.7 8.7e-20 71.0 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) CRAL_TRIO_N PF03765.15 KFQ91522.1 - 0.056 13.6 1.4 0.073 13.3 0.2 1.7 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain TPR_10 PF13374.6 KFQ91523.1 - 4.7e-24 83.5 4.9 1.4e-08 34.3 0.0 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ91523.1 - 3.1e-23 81.9 22.1 5.7e-10 39.4 0.8 7.1 4 3 3 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ91523.1 - 7.4e-09 35.0 2.6 0.0017 18.2 0.1 5.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ91523.1 - 1.2e-05 24.9 24.0 0.00035 20.3 0.2 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ91523.1 - 4.4e-05 23.4 17.3 0.041 14.1 0.3 7.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ91523.1 - 5e-05 23.1 13.4 7.7 6.9 0.3 7.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFQ91523.1 - 0.0011 18.5 10.6 0.086 12.2 2.1 3.3 1 1 2 3 3 3 3 MalT-like TPR region PP2C PF00481.21 KFQ91524.1 - 1.2e-60 205.4 0.0 1.6e-60 204.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFQ91524.1 - 0.15 11.6 0.0 1.1 8.9 0.0 2.1 2 1 0 2 2 2 0 Protein phosphatase 2C BCAS3 PF12490.8 KFQ91525.1 - 2.2e-29 102.7 0.0 3.6e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 3 WD40 PF00400.32 KFQ91525.1 - 0.0001 23.0 1.3 0.02 15.7 0.1 3.1 2 0 0 2 2 2 2 WD domain, G-beta repeat CTP_transf_1 PF01148.20 KFQ91525.1 - 0.064 13.0 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase family T-box PF00907.22 KFQ91526.1 - 2.9e-57 193.9 0.1 3.9e-57 193.5 0.1 1.1 1 0 0 1 1 1 1 T-box TBX PF12598.8 KFQ91526.1 - 8.4e-21 74.6 2.0 8.4e-21 74.6 2.0 2.5 2 0 0 2 2 2 1 T-box transcription factor T-box PF00907.22 KFQ91527.1 - 1.2e-53 182.1 0.1 9.9e-47 159.6 0.0 2.4 2 0 0 2 2 2 2 T-box Helicase_C_2 PF13307.6 KFQ91528.1 - 1.1e-53 181.9 0.0 2.3e-53 180.9 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KFQ91528.1 - 3.6e-49 166.8 0.2 3.6e-49 166.8 0.2 2.4 3 0 0 3 3 3 1 DEAD_2 DEAD PF00270.29 KFQ91528.1 - 9.1e-06 25.6 0.0 3e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase HBB PF06777.11 KFQ91528.1 - 0.00044 20.0 0.0 0.00095 18.9 0.0 1.5 1 0 0 1 1 1 1 Helical and beta-bridge domain ResIII PF04851.15 KFQ91528.1 - 0.0015 18.5 0.0 0.15 12.0 0.0 2.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit INTS2 PF14750.6 KFQ91529.1 - 0 1610.7 22.1 0 1610.5 22.1 1.0 1 0 0 1 1 1 1 Integrator complex subunit 2 Vitellogenin_N PF01347.22 KFQ91529.1 - 0.0024 16.4 0.0 0.0038 15.7 0.0 1.2 1 0 0 1 1 1 1 Lipoprotein amino terminal region Med13_C PF06333.12 KFQ91530.1 - 1.3e-118 396.1 0.1 1.3e-118 396.1 0.1 4.6 5 1 1 6 6 6 1 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 KFQ91530.1 - 5.1e-97 324.5 4.4 5.1e-97 324.5 4.4 3.2 3 1 0 3 3 3 1 MID domain of medPIWI Med13_N PF11597.8 KFQ91530.1 - 2.4e-25 89.6 0.0 6.9e-25 88.1 0.0 1.8 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal zf-C3HC4_3 PF13920.6 KFQ91531.1 - 1.3e-10 41.0 7.5 2.3e-10 40.2 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ91531.1 - 1.4e-09 38.2 11.2 3.2e-09 37.0 11.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFQ91531.1 - 1.6e-09 37.5 10.7 2.9e-09 36.6 10.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFQ91531.1 - 3.9e-09 36.4 7.9 9e-09 35.2 7.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFQ91531.1 - 2.6e-08 33.6 11.7 5.5e-08 32.6 11.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFQ91531.1 - 1.6e-07 31.1 8.6 2.8e-07 30.3 8.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFQ91531.1 - 2.4e-07 30.6 9.8 5.5e-07 29.4 9.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFQ91531.1 - 3.4e-07 30.4 10.1 7.6e-07 29.3 10.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KFQ91531.1 - 1.6e-05 25.0 11.3 3.2e-05 24.0 11.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KFQ91531.1 - 0.0015 18.4 3.1 0.0034 17.2 3.1 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 KFQ91531.1 - 0.013 15.5 7.2 0.43 10.7 7.2 2.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFQ91531.1 - 0.075 12.7 5.8 0.15 11.7 5.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KFQ91531.1 - 0.88 9.4 8.9 2.3 8.1 8.9 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-Nse PF11789.8 KFQ91531.1 - 1.3 8.9 7.6 2.3 8.1 7.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit CTU2 PF10288.9 KFQ91531.1 - 1.5 9.1 5.3 35 4.7 5.3 2.1 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-P11 PF03854.14 KFQ91531.1 - 2.3 7.9 8.0 8 6.2 7.8 2.0 1 1 0 1 1 1 0 P-11 zinc finger DZR PF12773.7 KFQ91531.1 - 2.9 8.0 8.2 7.1 6.8 8.3 1.7 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_5 PF17121.5 KFQ91531.1 - 3.8 7.5 8.8 67 3.5 8.8 3.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KFQ91531.1 - 4.1 7.3 9.5 0.35 10.7 3.4 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Pkinase PF00069.25 KFQ91532.1 - 7.2e-70 235.4 0.0 1.3e-69 234.5 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ91532.1 - 5.2e-37 127.5 0.0 6.7e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KFQ91532.1 - 3e-10 40.6 3.7 7.4e-10 39.4 3.7 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFQ91532.1 - 2e-07 30.6 0.0 6.6e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFQ91532.1 - 0.00018 20.4 0.1 0.00028 19.8 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KFQ91532.1 - 0.036 13.7 0.1 5 6.7 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFQ91532.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFQ91532.1 - 0.19 10.6 0.1 0.28 10.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KFQ91532.1 - 0.25 10.7 0.2 0.4 10.0 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PTH2 PF01981.16 KFQ91533.1 - 2e-47 160.3 0.0 2.5e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Clathrin PF00637.20 KFQ91534.1 - 1.3e-208 683.2 39.9 1.8e-34 118.7 1.4 7.9 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KFQ91534.1 - 3e-50 166.2 3.1 3.1e-08 33.5 0.0 6.7 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 KFQ91534.1 - 1.1e-32 111.7 0.4 7.1e-32 109.1 0.3 2.6 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.10 KFQ91534.1 - 1e-14 53.5 0.7 3.1e-14 52.0 0.7 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 KFQ91534.1 - 1.6e-07 30.8 4.8 1.4e-05 24.4 0.3 4.0 4 0 0 4 4 4 1 Coatomer WD associated region TPR_7 PF13176.6 KFQ91534.1 - 0.00011 22.0 11.4 1.5 9.1 0.1 8.1 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ91534.1 - 0.00045 20.7 3.9 4.1 8.0 0.1 6.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ91534.1 - 0.00097 18.9 7.2 0.27 11.1 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ91534.1 - 0.0049 16.9 8.9 4.5 7.6 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ91534.1 - 0.016 16.0 22.5 24 6.1 0.0 9.2 8 1 1 9 9 8 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ91534.1 - 0.04 14.1 3.1 12 6.2 0.1 5.3 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Ovate PF04844.13 KFQ91534.1 - 0.28 11.2 1.6 1.4 9.0 0.0 2.9 3 0 0 3 3 3 0 Transcriptional repressor, ovate HA2 PF04408.23 KFQ91535.1 - 1e-14 54.7 0.7 2e-14 53.7 0.0 1.9 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFQ91535.1 - 5.7e-14 52.2 0.0 1.1e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFQ91535.1 - 4.8e-13 49.4 0.0 1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFQ91535.1 - 1.6e-06 28.4 0.0 3.7e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KFQ91535.1 - 9.8e-06 25.4 0.2 3.4e-05 23.7 0.2 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4685 PF15737.5 KFQ91535.1 - 0.00012 22.5 1.6 0.12 12.8 0.6 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4685) T2SSE PF00437.20 KFQ91535.1 - 0.0022 17.1 0.3 0.038 13.0 0.0 2.7 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 KFQ91535.1 - 0.0033 17.2 0.0 0.015 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain SesA PF17107.5 KFQ91535.1 - 0.015 15.5 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_19 PF13245.6 KFQ91535.1 - 0.06 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Herpes_ori_bp PF02399.15 KFQ91535.1 - 0.069 11.2 0.0 0.097 10.7 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein Vicilin_N PF04702.12 KFQ91535.1 - 0.11 12.3 2.1 0.24 11.2 2.1 1.4 1 0 0 1 1 1 0 Vicilin N terminal region AAA_29 PF13555.6 KFQ91535.1 - 0.15 11.9 0.9 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KFQ91535.1 - 2.2 8.8 4.6 20 5.7 0.2 3.1 2 1 0 3 3 3 0 ABC transporter Yippee-Mis18 PF03226.14 KFQ91536.1 - 1.1e-12 48.0 0.2 1.5e-12 47.7 0.2 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly ATPgrasp_YheCD PF14398.6 KFQ91536.1 - 0.0091 15.3 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 YheC/D like ATP-grasp RIG-I_C-RD PF11648.8 KFQ91536.1 - 0.034 14.4 0.4 0.069 13.4 0.4 1.5 1 1 0 1 1 1 0 C-terminal domain of RIG-I Evr1_Alr PF04777.13 KFQ91536.1 - 0.072 13.6 2.4 0.26 11.8 0.5 2.0 1 1 0 2 2 2 0 Erv1 / Alr family zf-CHY PF05495.12 KFQ91536.1 - 0.094 13.2 7.3 0.41 11.2 7.3 1.9 1 1 0 1 1 1 0 CHY zinc finger Elf1 PF05129.13 KFQ91536.1 - 0.1 12.7 0.9 4.6 7.3 0.1 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like GDPD PF03009.17 KFQ91537.1 - 1.5e-30 106.8 0.3 4.7e-23 82.2 0.2 2.0 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KFQ91537.1 - 0.0041 17.5 0.0 0.0081 16.6 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF4954 PF16314.5 KFQ91537.1 - 0.07 11.2 0.2 0.1 10.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) PI-PLC-X PF00388.19 KFQ91537.1 - 0.076 12.6 0.3 0.46 10.1 0.1 2.1 2 0 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, X domain Smg8_Smg9 PF10220.9 KFQ91538.1 - 0 1145.0 0.0 0 1144.9 0.0 1.0 1 0 0 1 1 1 1 Smg8_Smg9 CAP_N PF01213.19 KFQ91539.1 - 4.4 6.7 10.4 8.6 5.7 10.4 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SKA2 PF16740.5 KFQ91540.1 - 1.2e-24 86.2 2.0 1.3e-24 86.1 2.0 1.0 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 zf-B_box PF00643.24 KFQ91541.1 - 6.9e-09 35.7 8.7 6.9e-09 35.7 8.7 3.0 2 1 1 3 3 2 1 B-box zinc finger MATH PF00917.26 KFQ91541.1 - 3.1e-08 33.7 0.0 9.3e-08 32.2 0.0 1.9 1 0 0 1 1 1 1 MATH domain zf-C3HC4_3 PF13920.6 KFQ91541.1 - 1.9e-05 24.4 15.1 1.9e-05 24.4 15.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFQ91541.1 - 0.0035 17.1 17.1 0.0035 17.1 17.1 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) HlyD_2 PF12700.7 KFQ91541.1 - 0.012 14.4 4.7 0.021 13.6 4.7 1.3 1 0 0 1 1 1 0 HlyD family secretion protein Baculo_PEP_C PF04513.12 KFQ91541.1 - 0.072 13.1 5.1 1.1 9.3 2.0 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus MRFAP1 PF15155.6 KFQ91541.1 - 0.14 12.7 3.3 0.17 12.4 1.4 2.1 2 0 0 2 2 2 0 MORF4 family-associated protein1 FUSC PF04632.12 KFQ91541.1 - 0.14 10.6 2.8 0.27 9.7 2.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF148 PF02520.17 KFQ91541.1 - 0.9 9.7 9.2 0.98 9.6 2.3 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF148 PIN_8 PF18476.1 KFQ91541.1 - 1 9.2 8.0 0.16 11.8 1.9 2.4 3 0 0 3 3 3 0 PIN like domain DUF2203 PF09969.9 KFQ91541.1 - 1.2 9.9 4.1 29 5.4 2.6 3.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF5071 PF16804.5 KFQ91541.1 - 2.8 8.2 5.3 34 4.7 5.4 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5071) Spc7 PF08317.11 KFQ91541.1 - 3.4 6.4 14.5 37 3.1 11.5 2.7 2 1 0 2 2 2 0 Spc7 kinetochore protein PP2C PF00481.21 KFQ91542.1 - 5.6e-64 216.2 0.2 7e-64 215.9 0.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFQ91542.1 - 0.0019 17.9 0.1 0.0058 16.3 0.1 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KFQ91542.1 - 0.0057 16.6 0.9 0.93 9.4 0.1 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Rad51 PF08423.11 KFQ91543.1 - 1.2e-44 152.6 0.0 2e-44 151.8 0.0 1.3 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KFQ91543.1 - 1.4e-06 28.0 0.0 4.3e-06 26.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 KFQ91543.1 - 6e-05 22.5 0.1 0.00011 21.6 0.1 1.4 1 0 0 1 1 1 1 KaiC RecA PF00154.21 KFQ91543.1 - 0.00014 21.5 0.1 0.0025 17.3 0.1 2.2 2 0 0 2 2 2 1 recA bacterial DNA recombination protein DnaB_C PF03796.15 KFQ91543.1 - 0.0031 16.9 0.0 0.0054 16.1 0.0 1.3 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_24 PF13479.6 KFQ91543.1 - 0.0073 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFQ91543.1 - 0.022 15.3 0.1 0.052 14.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFQ91543.1 - 0.12 12.7 0.0 0.34 11.3 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KFQ91543.1 - 0.13 12.5 1.5 0.78 10.0 0.1 2.6 2 2 1 3 3 3 0 AAA domain AAA_33 PF13671.6 KFQ91543.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFQ91543.1 - 0.14 12.0 0.1 0.31 11.0 0.1 1.7 1 1 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 KFQ91543.1 - 0.18 12.2 0.0 0.51 10.8 0.0 1.7 2 0 0 2 2 2 0 RNA helicase Pkinase_Tyr PF07714.17 KFQ91544.1 - 6.8e-27 94.4 1.3 1.5e-26 93.3 0.1 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ91544.1 - 1.1e-18 67.6 0.1 2.8e-18 66.3 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 KFQ91544.1 - 1e-06 29.2 0.0 4.7e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFQ91544.1 - 0.0002 21.5 0.1 0.088 13.4 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KFQ91544.1 - 0.0056 17.2 0.0 0.018 15.6 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFQ91544.1 - 0.034 14.5 0.0 0.087 13.2 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) 7tm_1 PF00001.21 KFQ91545.1 - 4.5e-44 150.8 13.3 5.6e-44 150.4 13.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFQ91545.1 - 2.5e-07 30.7 6.9 0.00052 19.8 1.5 2.1 2 0 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srv PF10323.9 KFQ91545.1 - 9e-06 25.2 11.5 1.2e-05 24.8 11.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.9 KFQ91545.1 - 0.00024 20.6 13.7 0.003 17.0 13.7 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 KFQ91545.1 - 0.0048 16.2 8.0 0.0048 16.2 8.0 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF4231 PF14015.6 KFQ91545.1 - 4.3 7.9 5.0 1.2 9.6 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) DUF2569 PF10754.9 KFQ91545.1 - 9.4 6.7 14.9 19 5.7 7.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2569) FAM101 PF15068.6 KFQ91546.1 - 3.8e-72 242.6 2.4 4.1e-72 242.5 2.4 1.0 1 0 0 1 1 1 1 FAM101 family Vps53_N PF04100.12 KFQ91547.1 - 1e-171 571.1 0.5 1.7e-171 570.3 0.5 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 KFQ91547.1 - 1.7e-07 30.8 1.8 1.7e-07 30.8 1.8 2.1 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex Spc7 PF08317.11 KFQ91547.1 - 4.2e-05 22.6 3.5 9.3e-05 21.5 3.5 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein VPS53_C PF16854.5 KFQ91547.1 - 0.00052 20.0 5.2 0.001 19.0 0.0 3.0 3 0 0 3 3 3 1 Vacuolar protein sorting-associated protein 53 C-terminus Laminin_II PF06009.12 KFQ91547.1 - 0.0038 17.3 4.8 0.007 16.4 3.4 2.1 2 0 0 2 2 2 1 Laminin Domain II Sec8_exocyst PF04048.14 KFQ91547.1 - 0.012 15.5 2.5 0.015 15.2 1.0 2.0 2 0 0 2 2 1 0 Sec8 exocyst complex component specific domain DUF2451 PF10474.9 KFQ91547.1 - 0.015 15.1 1.6 0.021 14.6 0.1 2.1 2 0 0 2 2 1 0 Protein of unknown function C-terminus (DUF2451) DUF4413 PF14372.6 KFQ91547.1 - 0.017 15.5 0.2 0.19 12.1 0.0 2.9 3 1 0 3 3 2 0 Domain of unknown function (DUF4413) NBD94 PF16830.5 KFQ91547.1 - 0.023 15.1 3.9 0.068 13.6 3.9 1.8 1 0 0 1 1 1 0 Nucleotide-Binding Domain 94 of RH LXG PF04740.12 KFQ91547.1 - 0.039 13.7 2.8 0.13 12.0 2.8 1.8 1 1 0 1 1 1 0 LXG domain of WXG superfamily Vps51 PF08700.11 KFQ91547.1 - 0.043 13.9 5.6 0.086 12.9 1.5 3.3 2 1 1 3 3 2 0 Vps51/Vps67 GrpE PF01025.19 KFQ91547.1 - 0.047 13.4 2.1 0.14 11.8 2.1 1.9 1 0 0 1 1 1 0 GrpE MCPsignal PF00015.21 KFQ91547.1 - 0.086 12.7 1.0 0.31 10.9 1.0 1.9 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Sec34 PF04136.15 KFQ91547.1 - 0.088 12.7 2.4 0.31 10.9 1.6 2.3 2 0 0 2 2 2 0 Sec34-like family ATG16 PF08614.11 KFQ91547.1 - 0.11 12.7 1.6 0.41 10.9 1.6 2.0 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 KFQ91547.1 - 0.12 12.4 11.0 4.3 7.4 6.0 4.4 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) BRE1 PF08647.11 KFQ91547.1 - 0.21 11.7 4.5 0.77 9.9 4.5 1.9 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Tropomyosin PF00261.20 KFQ91547.1 - 0.24 10.8 6.5 0.049 13.0 1.4 2.3 3 0 0 3 3 3 0 Tropomyosin COG5 PF10392.9 KFQ91547.1 - 0.26 11.5 2.6 0.32 11.2 0.9 2.1 2 0 0 2 2 1 0 Golgi transport complex subunit 5 Syntaxin_2 PF14523.6 KFQ91547.1 - 0.46 10.9 5.7 8.1 6.9 5.8 3.1 1 1 0 1 1 1 0 Syntaxin-like protein BLOC1_2 PF10046.9 KFQ91547.1 - 0.56 10.5 5.6 1.8 8.9 2.3 3.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 XhlA PF10779.9 KFQ91547.1 - 0.61 10.3 10.4 0.058 13.6 2.7 2.9 3 0 0 3 3 2 0 Haemolysin XhlA Seryl_tRNA_N PF02403.22 KFQ91547.1 - 0.68 10.2 8.3 0.27 11.5 3.1 2.9 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain COG2 PF06148.11 KFQ91547.1 - 1.3 9.1 5.8 2.4 8.2 2.9 3.0 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CREPT PF16566.5 KFQ91547.1 - 1.4 9.0 7.2 1.8 8.7 1.5 3.4 3 1 1 4 4 3 0 Cell-cycle alteration and expression-elevated protein in tumour Snf7 PF03357.21 KFQ91547.1 - 1.9 8.1 10.4 0.51 9.9 5.6 2.5 2 0 0 2 2 2 0 Snf7 ING PF12998.7 KFQ91547.1 - 2.7 8.6 9.9 0.26 11.9 4.2 2.4 3 0 0 3 3 1 0 Inhibitor of growth proteins N-terminal histone-binding Prefoldin PF02996.17 KFQ91547.1 - 3 7.8 7.5 18 5.3 1.5 3.7 2 1 2 4 4 4 0 Prefoldin subunit TRAM_LAG1_CLN8 PF03798.16 KFQ91548.1 - 4.4e-40 137.6 15.9 4.9e-40 137.4 15.9 1.0 1 0 0 1 1 1 1 TLC domain Mo25 PF08569.11 KFQ91549.1 - 0.094 12.1 0.9 3.3 7.0 0.1 2.4 2 0 0 2 2 2 0 Mo25-like Glyoxalase PF00903.25 KFQ91550.1 - 0.00068 19.8 0.0 0.0051 17.0 0.0 2.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KFQ91550.1 - 0.0047 17.7 0.0 5.5 7.8 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KFQ91550.1 - 0.077 13.3 0.0 0.17 12.2 0.0 1.8 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SpoU_methylase PF00588.19 KFQ91551.1 - 6.5e-25 88.0 0.0 1.4e-22 80.3 0.0 2.2 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KFQ91551.1 - 0.0031 17.8 0.0 0.009 16.3 0.0 1.8 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding Thioredoxin_8 PF13905.6 KFQ91552.1 - 3.9e-33 113.6 0.0 8.3e-29 99.8 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KFQ91552.1 - 1.5e-11 44.7 0.0 2.5e-08 34.3 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.20 KFQ91552.1 - 1.2e-08 34.9 0.0 5.4e-05 23.1 0.0 3.6 3 1 1 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 KFQ91552.1 - 6.1e-08 32.8 0.1 4.2e-07 30.1 0.0 2.3 4 0 0 4 4 4 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KFQ91552.1 - 7.2e-08 32.4 0.0 1.8e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFQ91552.1 - 1.1e-06 28.4 0.0 2.2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 KFQ91552.1 - 2e-05 24.7 0.0 0.0004 20.5 0.0 2.9 2 1 0 2 2 2 1 Thioredoxin-like SCO1-SenC PF02630.14 KFQ91552.1 - 6.5e-05 22.9 0.0 0.00033 20.6 0.0 2.0 2 0 0 2 2 2 1 SCO1/SenC HyaE PF07449.11 KFQ91552.1 - 0.00024 21.0 0.1 2.8 7.9 0.0 3.9 4 0 0 4 4 4 1 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 KFQ91552.1 - 0.00057 20.0 0.0 0.0065 16.7 0.1 2.5 2 0 0 2 2 2 1 Glutaredoxin MatE PF01554.18 KFQ91553.1 - 2.6e-49 167.0 30.6 1.7e-28 99.3 10.3 3.2 2 1 0 2 2 2 2 MatE ECF_trnsprt PF12822.7 KFQ91553.1 - 8.3 6.5 34.2 0.073 13.2 5.8 3.4 2 2 1 3 3 3 0 ECF transporter, substrate-specific component MatE PF01554.18 KFQ91554.1 - 1.5e-56 190.5 31.6 3.1e-29 101.7 9.5 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KFQ91554.1 - 3.1e-06 27.3 14.0 3.1e-06 27.3 14.0 3.5 4 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain CPSase_L_D2 PF02786.17 KFQ91555.1 - 3.5e-86 288.1 0.0 6e-86 287.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KFQ91555.1 - 8.8e-37 125.5 0.0 2e-36 124.4 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain PCC_BT PF18140.1 KFQ91555.1 - 6.3e-30 104.1 0.0 1.9e-29 102.6 0.0 1.9 1 0 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain Biotin_carb_N PF00289.22 KFQ91555.1 - 2.4e-29 102.1 0.9 6.9e-29 100.6 0.4 2.1 2 1 0 2 2 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KFQ91555.1 - 2e-11 43.6 2.1 2e-11 43.6 2.1 2.4 3 0 0 3 3 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KFQ91555.1 - 1.5e-08 34.4 0.0 6.1e-08 32.5 0.0 1.9 1 1 1 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFQ91555.1 - 2.7e-07 30.3 0.0 6.4e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KFQ91555.1 - 0.00029 20.5 0.0 0.00054 19.6 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 KFQ91555.1 - 0.00037 20.6 0.0 0.00096 19.2 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KFQ91555.1 - 0.00078 19.2 0.0 0.0027 17.5 0.0 1.9 2 0 0 2 2 2 1 Biotin-lipoyl like ATP-grasp_5 PF13549.6 KFQ91555.1 - 0.016 14.7 0.1 0.063 12.7 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain SLT_beta PF02258.16 KFQ91555.1 - 0.041 13.9 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Shiga-like toxin beta subunit HlyD_3 PF13437.6 KFQ91555.1 - 0.069 13.8 0.0 0.19 12.4 0.0 1.8 1 0 0 1 1 1 0 HlyD family secretion protein ATPgrasp_ST PF14397.6 KFQ91555.1 - 0.082 12.1 0.0 0.35 10.1 0.0 1.9 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp GARS_A PF01071.19 KFQ91555.1 - 0.091 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GGACT PF06094.12 KFQ91556.1 - 1.5e-22 80.5 0.2 1.8e-22 80.2 0.2 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 KFQ91556.1 - 0.067 13.6 0.0 0.13 12.6 0.0 1.7 1 1 0 1 1 1 0 AIG2-like family TPR_1 PF00515.28 KFQ91557.1 - 2e-34 116.0 19.1 5.8e-05 22.7 0.1 7.6 7 0 0 7 7 7 7 Tetratricopeptide repeat DUF1736 PF08409.11 KFQ91557.1 - 3.7e-33 113.3 2.7 7.4e-33 112.4 2.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_2 PF07719.17 KFQ91557.1 - 3.4e-29 98.6 17.3 1.1e-05 25.1 0.3 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ91557.1 - 1.1e-27 93.8 9.7 5.7e-05 23.0 0.2 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ91557.1 - 1.3e-26 91.0 20.9 6.1e-06 26.3 0.3 7.9 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ91557.1 - 1.4e-24 86.5 5.7 1.1e-07 32.3 0.1 4.8 3 1 1 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ91557.1 - 1.4e-24 85.5 17.6 2.2e-06 27.2 0.3 8.0 2 2 6 8 8 8 5 TPR repeat TPR_12 PF13424.6 KFQ91557.1 - 9.5e-19 67.5 13.7 1.5e-06 28.4 0.2 5.8 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ91557.1 - 2.8e-16 58.8 7.7 0.0044 17.7 0.1 8.0 3 1 6 9 9 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ91557.1 - 2.2e-14 52.8 22.1 5.7e-05 22.9 0.5 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ91557.1 - 1.2e-13 51.3 10.1 2.5e-06 27.9 0.9 5.2 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ91557.1 - 4.2e-10 38.9 5.3 4.6 7.5 0.0 6.9 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_4 PF07721.14 KFQ91557.1 - 8.1e-05 22.9 0.3 3.8 8.4 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFQ91557.1 - 0.00027 20.2 7.4 0.011 15.0 1.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFQ91557.1 - 0.00048 19.6 5.0 0.13 11.6 0.3 3.2 1 1 2 3 3 3 2 MalT-like TPR region NARP1 PF12569.8 KFQ91557.1 - 0.0018 17.2 3.0 0.05 12.5 0.2 2.5 1 1 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 KFQ91557.1 - 0.0044 17.6 3.2 16 6.4 0.0 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFQ91557.1 - 0.0082 16.3 3.9 0.11 12.6 0.1 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 KFQ91557.1 - 0.078 13.3 3.0 0.99 9.8 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 KFQ91557.1 - 0.15 12.5 1.8 0.84 10.1 0.1 2.3 2 0 0 2 2 2 0 Bacterial transcriptional activator domain FAT PF02259.23 KFQ91557.1 - 0.17 11.1 5.3 0.029 13.6 1.4 1.8 2 0 0 2 2 2 0 FAT domain ANAPC3 PF12895.7 KFQ91557.1 - 0.41 10.9 5.5 3.2 8.1 0.4 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 KFQ91557.1 - 5.6 7.1 6.7 14 5.8 0.8 4.0 3 2 1 4 4 3 0 MIT (microtubule interacting and transport) domain EGF_2 PF07974.13 KFQ91560.1 - 5e-43 145.1 210.6 6.2e-08 32.9 16.8 11.0 9 4 2 11 11 11 9 EGF-like domain I-EGF_1 PF18372.1 KFQ91560.1 - 3.2e-05 23.9 199.3 0.0084 16.2 11.7 13.0 14 1 1 15 15 15 9 Integrin beta epidermal growth factor like domain 1 FGF PF00167.18 KFQ91561.1 - 6.3e-41 139.4 0.0 7.7e-41 139.1 0.0 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.13 KFQ91561.1 - 0.008 16.4 0.0 0.02 15.1 0.0 1.6 2 0 0 2 2 2 1 Fascin domain CDtoxinA PF03498.14 KFQ91561.1 - 0.18 11.4 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain Peptidase_S8 PF00082.22 KFQ91563.1 - 1.2e-96 323.5 1.2 1.7e-96 323.0 1.2 1.3 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.8 KFQ91563.1 - 3.3e-80 268.1 0.1 8.2e-80 266.8 0.0 1.7 2 0 0 2 2 2 1 Tripeptidyl peptidase II TPPII_N PF12583.8 KFQ91563.1 - 0.0006 20.4 0.2 0.0012 19.4 0.2 1.4 1 0 0 1 1 1 1 Tripeptidyl peptidase II N terminal Methyltransf_16 PF10294.9 KFQ91564.1 - 5.6e-31 107.6 0.0 7.3e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KFQ91564.1 - 2.6e-07 30.6 0.0 3.8e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFQ91564.1 - 2.4e-05 24.9 0.0 4.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFQ91564.1 - 3e-05 23.6 0.0 4.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KFQ91564.1 - 0.00032 21.4 0.0 0.00061 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFQ91564.1 - 0.00044 20.9 0.0 0.001 19.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain TehB PF03848.14 KFQ91564.1 - 0.029 13.8 0.0 0.06 12.8 0.0 1.5 1 1 0 1 1 1 0 Tellurite resistance protein TehB DREV PF05219.12 KFQ91564.1 - 0.078 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase DUF938 PF06080.12 KFQ91564.1 - 0.079 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) MTS PF05175.14 KFQ91564.1 - 0.088 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 KFQ91564.1 - 0.13 12.0 0.0 0.7 9.7 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Hydrolase_4 PF12146.8 KFQ91565.1 - 1.5e-06 27.7 0.1 0.042 13.1 0.1 2.6 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 KFQ91565.1 - 0.0022 17.6 0.0 0.0039 16.8 0.0 1.5 2 0 0 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.13 KFQ91565.1 - 0.003 17.2 0.0 0.0043 16.7 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 KFQ91565.1 - 0.066 13.0 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KFQ91565.1 - 0.095 12.4 0.0 2.7 7.6 0.0 2.3 2 0 0 2 2 2 0 PGAP1-like protein Glyco_transf_90 PF05686.12 KFQ91566.1 - 2.6e-111 372.3 1.7 3.6e-111 371.9 1.7 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Filamin PF00630.19 KFQ91566.1 - 3.7e-07 30.9 0.1 7.2e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 Filamin/ABP280 repeat Glyco_trans_1_2 PF13524.6 KFQ91566.1 - 2.4e-05 24.6 0.0 4.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 XPG_N PF00752.17 KFQ91568.1 - 5e-33 113.6 0.0 1.8e-32 111.8 0.0 2.1 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KFQ91568.1 - 5.2e-25 87.6 0.0 4e-24 84.8 0.0 2.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 KFQ91568.1 - 0.0022 18.5 0.0 0.014 16.0 0.0 2.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Methyltransf_16 PF10294.9 KFQ91569.1 - 9.7e-33 113.3 0.0 1.3e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KFQ91569.1 - 1.9e-07 31.0 0.0 2.5e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFQ91569.1 - 0.00029 20.3 0.0 0.00037 20.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 KFQ91569.1 - 0.023 15.4 0.0 0.05 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KFQ91569.1 - 0.035 14.8 0.0 0.066 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ephrin PF00812.17 KFQ91572.1 - 1.4e-51 174.1 0.3 1.4e-50 170.9 0.1 2.0 2 0 0 2 2 2 1 Ephrin TMEM132D_C PF15706.5 KFQ91572.1 - 0.002 17.8 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term RIFIN PF02009.16 KFQ91572.1 - 0.045 13.6 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 Rifin OSTbeta PF15048.6 KFQ91572.1 - 0.053 13.7 0.1 12 6.1 0.0 2.4 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein EphA2_TM PF14575.6 KFQ91572.1 - 0.069 14.0 0.0 0.15 13.0 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KFQ91572.1 - 0.074 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family ECSCR PF15820.5 KFQ91572.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Amnionless PF14828.6 KFQ91572.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Amnionless UL45 PF05473.12 KFQ91572.1 - 0.15 11.6 0.2 0.71 9.5 0.0 2.2 3 0 0 3 3 3 0 UL45 protein, carbohydrate-binding C-type lectin-like Stevor PF17410.2 KFQ91572.1 - 0.16 11.5 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame ARGLU PF15346.6 KFQ91573.1 - 9.4e-53 178.1 59.2 1.1e-52 178.0 59.2 1.0 1 0 0 1 1 1 1 Arginine and glutamate-rich 1 Atg14 PF10186.9 KFQ91573.1 - 4.3 6.3 31.1 5 6.1 31.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Asp-B-Hydro_N PF05279.11 KFQ91573.1 - 5.4 7.0 35.7 6.4 6.8 35.7 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Fz PF01392.22 KFQ91575.1 - 6.2 7.5 10.3 0.25 12.0 3.7 1.9 1 1 1 2 2 2 0 Fz domain DNA_ligase_A_M PF01068.21 KFQ91579.1 - 4.1e-54 183.3 0.3 8.5e-54 182.3 0.3 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KFQ91579.1 - 9.5e-42 143.2 0.2 1.9e-41 142.3 0.2 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_IV PF11411.8 KFQ91579.1 - 2.6e-19 69.1 1.4 5.9e-19 67.9 1.4 1.7 1 0 0 1 1 1 1 DNA ligase IV DNA_ligase_A_C PF04679.15 KFQ91579.1 - 2.8e-18 66.3 0.0 1.3e-17 64.2 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.26 KFQ91579.1 - 1.9e-16 60.2 0.2 7e-11 42.4 0.0 3.4 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KFQ91579.1 - 2.9e-13 50.0 0.1 1.4e-10 41.4 0.0 2.8 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 KFQ91579.1 - 8.7e-11 42.4 0.3 2.3e-10 41.0 0.1 1.9 2 0 0 2 2 2 1 RNA ligase mRNA_cap_enzyme PF01331.19 KFQ91579.1 - 0.0076 16.1 0.7 0.091 12.6 0.7 2.3 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain Tox-REase-9 PF15650.6 KFQ91579.1 - 0.071 13.4 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 9 LIG3_BRCT PF16759.5 KFQ91579.1 - 0.099 13.0 0.1 0.87 9.9 0.0 2.4 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain SKA1 PF07160.12 KFQ91579.1 - 0.27 11.1 3.1 0.28 11.0 1.1 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Abhydrolase_1 PF00561.20 KFQ91580.1 - 5.2e-16 59.1 0.0 2.4e-10 40.5 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFQ91580.1 - 7.2e-16 58.2 0.0 2.8e-10 39.9 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 AXE1 PF05448.12 KFQ91580.1 - 2.7e-08 32.9 0.0 0.00028 19.7 0.0 3.1 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 KFQ91580.1 - 4.7e-06 27.4 0.0 4e-05 24.3 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KFQ91580.1 - 0.00011 22.1 0.0 0.0071 16.2 0.0 2.6 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KFQ91580.1 - 0.0005 20.0 0.0 0.00067 19.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KFQ91580.1 - 0.001 18.7 0.0 0.019 14.6 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KFQ91580.1 - 0.0011 18.5 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 KFQ91580.1 - 0.0013 18.7 0.0 0.0076 16.2 0.0 2.0 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 KFQ91580.1 - 0.0027 17.4 0.0 0.0037 16.9 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 KFQ91580.1 - 0.012 15.2 0.0 0.064 12.8 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family Esterase PF00756.20 KFQ91580.1 - 0.042 13.5 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF1057 PF06342.12 KFQ91580.1 - 0.054 12.5 0.0 0.078 12.0 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) PGAP1 PF07819.13 KFQ91580.1 - 0.18 11.5 0.1 0.45 10.2 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein DUF5339 PF17274.2 KFQ91580.1 - 0.2 12.5 0.0 0.33 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5339) TNF PF00229.18 KFQ91581.1 - 3.9e-10 39.8 0.0 6.6e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family TGF_beta PF00019.20 KFQ91582.1 - 6.5e-29 101.0 1.7 1.3e-28 100.0 1.7 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFQ91582.1 - 6.3e-21 75.2 0.0 7.6e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 TGF-beta propeptide SAP PF02037.27 KFQ91583.1 - 5.6e-10 38.7 1.4 1.2e-08 34.5 0.9 2.6 2 0 0 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 KFQ91583.1 - 0.0061 16.3 17.4 0.47 10.3 1.6 4.8 1 1 4 5 5 5 4 Tho1/MOS11 C-terminal domain HCMV_UL139 PF12507.8 KFQ91583.1 - 1.4 9.3 5.8 11 6.4 0.5 2.8 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein ORMDL PF04061.14 KFQ91584.1 - 1.3e-53 180.5 1.8 1.4e-53 180.3 1.8 1.0 1 0 0 1 1 1 1 ORMDL family YlaC PF10777.9 KFQ91584.1 - 0.86 9.4 3.0 0.91 9.3 1.0 1.8 2 0 0 2 2 2 0 Inner membrane protein YlaC Ras PF00071.22 KFQ91585.1 - 2.7e-61 205.9 0.2 3.3e-61 205.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ91585.1 - 8.1e-36 122.9 0.0 1.8e-35 121.7 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ91585.1 - 2.3e-12 46.7 0.0 2.8e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFQ91585.1 - 9.2e-05 22.5 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFQ91585.1 - 9.6e-05 21.8 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFQ91585.1 - 0.00022 20.9 0.0 0.00053 19.6 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFQ91585.1 - 0.00025 21.0 0.2 0.26 11.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KFQ91585.1 - 0.011 16.1 0.1 0.021 15.2 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KFQ91585.1 - 0.06 13.6 0.1 1.2 9.4 0.0 2.1 1 1 1 2 2 2 0 AAA domain zf-H2C2_2 PF13465.6 KFQ91586.1 - 2.9e-19 68.5 32.9 4.9e-08 33.1 2.8 6.1 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ91586.1 - 1.6e-17 62.9 43.3 6.6e-05 23.2 1.3 6.4 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ91586.1 - 1.1e-12 47.6 40.8 0.00073 20.2 1.1 6.5 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFQ91586.1 - 1.1e-05 25.1 30.5 0.0011 18.6 1.1 5.0 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFQ91586.1 - 0.001 19.3 25.6 0.59 10.5 0.0 5.6 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFQ91586.1 - 0.0085 15.9 2.5 0.13 12.0 0.1 2.8 1 1 1 2 2 2 1 GAGA factor zf-C2H2_6 PF13912.6 KFQ91586.1 - 0.014 15.4 4.1 0.014 15.4 4.1 6.5 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFQ91586.1 - 0.045 14.1 10.9 0.13 12.6 2.7 3.2 2 1 1 3 3 3 0 C2H2-type zinc ribbon DUF4764 PF15961.5 KFQ91586.1 - 0.08 11.6 3.1 0.14 10.9 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4764) zf-C2H2_11 PF16622.5 KFQ91586.1 - 0.096 12.5 0.3 0.096 12.5 0.3 4.2 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-met PF12874.7 KFQ91586.1 - 0.25 11.8 0.1 0.25 11.8 0.1 6.0 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KFQ91586.1 - 0.69 10.4 21.9 0.75 10.3 1.2 5.5 5 1 1 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 KFQ91586.1 - 1 9.7 21.8 4.7 7.6 0.2 4.9 2 2 3 5 5 5 0 C2H2 type zinc-finger (2 copies) DUF3268 PF11672.8 KFQ91586.1 - 3.5 8.0 9.1 1.8 8.9 0.6 3.3 2 1 1 3 3 3 0 zinc-finger-containing domain zf-RING_7 PF02591.15 KFQ91586.1 - 9.7 6.5 10.3 1.6e+02 2.6 0.0 5.0 5 0 0 5 5 5 0 C4-type zinc ribbon domain Peptidase_M24 PF00557.24 KFQ91587.1 - 5e-21 75.4 0.2 5.8e-21 75.2 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-CCCH PF00642.24 KFQ91588.1 - 1.6e-13 50.2 16.9 1.3e-07 31.3 0.4 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KFQ91588.1 - 4e-10 39.3 17.3 0.0002 21.1 1.4 3.3 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFQ91588.1 - 2.9e-08 33.5 29.6 4.4e-05 23.4 4.4 3.9 4 0 0 4 4 4 2 Zinc finger domain zf-CCCH_2 PF14608.6 KFQ91588.1 - 3e-08 33.8 21.6 0.00022 21.6 2.7 3.4 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KFQ91588.1 - 2.1e-05 25.2 10.4 0.007 17.1 0.3 3.4 1 1 2 3 3 3 2 Torus domain zf-CCCH_3 PF15663.5 KFQ91588.1 - 0.00052 20.2 9.8 0.0067 16.6 4.6 2.6 2 0 0 2 2 2 1 Zinc-finger containing family TSC22 PF01166.18 KFQ91588.1 - 0.006 16.9 4.3 0.0064 16.8 2.6 1.9 1 1 1 2 2 2 1 TSC-22/dip/bun family bZIP_1 PF00170.21 KFQ91588.1 - 0.011 15.8 1.6 0.027 14.6 1.6 1.7 1 0 0 1 1 1 0 bZIP transcription factor MbeD_MobD PF04899.12 KFQ91588.1 - 0.022 14.8 0.8 0.08 13.1 0.1 2.2 2 1 0 2 2 2 0 MbeD/MobD like NRBF2 PF08961.10 KFQ91588.1 - 0.026 14.1 0.4 0.044 13.4 0.4 1.3 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator bZIP_2 PF07716.15 KFQ91588.1 - 0.94 9.6 5.7 1.6 8.9 4.0 2.3 1 1 1 2 2 2 0 Basic region leucine zipper PDCD9 PF07147.12 KFQ91589.1 - 2.3e-139 465.5 0.0 2.7e-139 465.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) TBCA PF02970.16 KFQ91590.1 - 1.1e-19 70.5 5.3 1.2e-19 70.4 5.3 1.0 1 0 0 1 1 1 1 Tubulin binding cofactor A SCAMP PF04144.13 KFQ91591.1 - 2.7e-69 232.9 18.5 3.2e-69 232.7 18.5 1.0 1 0 0 1 1 1 1 SCAMP family DUF3552 PF12072.8 KFQ91591.1 - 0.7 9.3 6.1 1.1 8.7 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) L_HMGIC_fpl PF10242.9 KFQ91592.1 - 1.2e-54 185.3 5.4 1.3e-54 185.2 5.4 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Nucleos_tra2_C PF07662.13 KFQ91592.1 - 0.0017 18.3 0.7 0.0017 18.3 0.7 1.4 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Claudin_3 PF06653.11 KFQ91592.1 - 0.0051 16.8 5.0 0.0074 16.2 5.0 1.2 1 0 0 1 1 1 1 Tight junction protein, Claudin-like PMP22_Claudin PF00822.20 KFQ91592.1 - 0.033 14.1 12.5 0.051 13.4 12.5 1.3 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFQ91592.1 - 0.06 13.1 10.2 0.11 12.2 10.2 1.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Sulfatase PF00884.23 KFQ91593.1 - 3.1e-48 164.7 0.0 5.9e-48 163.8 0.0 1.4 2 0 0 2 2 2 1 Sulfatase Sulfatase_C PF14707.6 KFQ91593.1 - 0.00047 20.9 0.1 0.0058 17.4 0.0 2.2 2 0 0 2 2 2 1 C-terminal region of aryl-sulfatase DUF1501 PF07394.12 KFQ91593.1 - 0.011 14.9 0.0 0.032 13.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) DUF4994 PF16385.5 KFQ91593.1 - 0.026 14.5 0.0 0.076 12.9 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function Phosphodiest PF01663.22 KFQ91593.1 - 0.044 13.4 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase GCV_T PF01571.21 KFQ91594.1 - 9.5e-71 238.2 0.0 1.3e-70 237.7 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 KFQ91594.1 - 3.4e-63 214.3 0.1 5e-63 213.8 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T_C PF08669.11 KFQ91594.1 - 2.2e-21 75.6 0.0 5.8e-21 74.2 0.0 1.8 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 KFQ91594.1 - 7.9e-13 48.5 0.1 1.7e-12 47.4 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain Pyr_redox_3 PF13738.6 KFQ91594.1 - 5.5e-08 32.4 0.0 0.00011 21.6 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SoxG PF04268.12 KFQ91594.1 - 5.4e-06 26.6 0.0 1.3e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 Sarcosine oxidase, gamma subunit family FAD_binding_2 PF00890.24 KFQ91594.1 - 4.5e-05 22.7 0.1 9.4e-05 21.7 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KFQ91594.1 - 8.8e-05 22.7 0.9 0.00063 19.9 0.6 2.4 1 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFQ91594.1 - 0.00048 19.4 0.2 0.00089 18.6 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KFQ91594.1 - 0.00074 18.8 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFQ91594.1 - 0.0028 17.0 0.3 0.0048 16.2 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 KFQ91594.1 - 0.015 14.9 0.1 0.035 13.7 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 KFQ91594.1 - 0.017 14.2 0.1 0.027 13.5 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 KFQ91594.1 - 0.023 15.3 0.2 0.069 13.7 0.1 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFQ91594.1 - 0.051 13.6 0.1 0.19 11.7 0.1 2.0 3 0 0 3 3 1 0 FAD-NAD(P)-binding MRPL52 PF18699.1 KFQ91594.1 - 0.067 13.4 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Mitoribosomal protein mL52 HI0933_like PF03486.14 KFQ91594.1 - 0.098 11.3 0.0 0.87 8.2 0.1 2.4 3 0 0 3 3 3 0 HI0933-like protein S-methyl_trans PF02574.16 KFQ91595.1 - 1e-50 173.0 0.0 1.3e-50 172.7 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase JMY PF15871.5 KFQ91596.1 - 2.8e-151 503.9 22.9 2.8e-151 503.9 22.9 2.5 2 1 0 2 2 2 1 Junction-mediating and -regulatory protein WH2 PF02205.20 KFQ91596.1 - 0.0018 18.0 0.2 0.0018 18.0 0.2 3.4 4 0 0 4 4 4 1 WH2 motif GAT PF03127.14 KFQ91596.1 - 0.44 10.9 7.8 0.15 12.4 0.7 3.2 3 0 0 3 3 3 0 GAT domain PRIMA1 PF16101.5 KFQ91596.1 - 3.2 7.8 9.1 8.4 6.5 9.1 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 MENTAL PF10457.9 KFQ91597.1 - 3.1e-63 212.8 8.7 3.5e-63 212.6 8.7 1.0 1 0 0 1 1 1 1 Cholesterol-capturing domain DUF2070 PF09843.9 KFQ91597.1 - 7.7 4.7 9.9 9 4.4 9.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Pecanex_C PF05041.15 KFQ91598.1 - 3.4e-114 380.1 0.0 4.9e-114 379.6 0.0 1.2 1 0 0 1 1 1 1 Pecanex protein (C-terminus) NTPase_1 PF03266.15 KFQ91599.1 - 6.9e-56 188.8 0.2 7.7e-56 188.6 0.2 1.0 1 0 0 1 1 1 1 NTPase AAA_30 PF13604.6 KFQ91599.1 - 0.016 14.9 0.1 0.06 13.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KFQ91599.1 - 0.087 12.9 0.0 11 6.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KFQ91599.1 - 0.16 11.9 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain MobB PF03205.14 KFQ91599.1 - 0.17 11.8 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B HPHLAWLY PF14925.6 KFQ91600.1 - 2.7e-80 270.9 34.7 6.6e-76 256.4 28.5 2.9 1 1 1 2 2 2 2 Domain of unknown function SPAR_C PF11881.8 KFQ91601.1 - 7.2e-70 235.6 0.1 2.6e-69 233.8 0.1 2.0 1 0 0 1 1 1 1 C-terminal domain of SPAR protein Rap_GAP PF02145.15 KFQ91601.1 - 4.9e-67 225.1 0.0 1e-66 224.0 0.0 1.6 1 0 0 1 1 1 1 Rap/ran-GAP PDZ_6 PF17820.1 KFQ91601.1 - 1.5e-05 24.7 0.0 3.3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFQ91601.1 - 2.4e-05 24.6 0.0 4.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain bZIP_2 PF07716.15 KFQ91601.1 - 0.37 10.9 4.8 1.5 9.0 4.8 2.1 1 0 0 1 1 1 0 Basic region leucine zipper DivIC PF04977.15 KFQ91601.1 - 5.8 6.8 5.5 13 5.6 5.5 1.5 1 0 0 1 1 1 0 Septum formation initiator Laminin_II PF06009.12 KFQ91602.1 - 0.011 15.8 0.4 0.011 15.8 0.4 4.6 4 1 1 5 5 5 0 Laminin Domain II UVR PF02151.19 KFQ91602.1 - 0.011 15.5 8.6 0.011 15.5 8.6 3.2 3 0 0 3 3 3 0 UvrB/uvrC motif Baculo_PEP_C PF04513.12 KFQ91602.1 - 0.05 13.7 11.3 7.5 6.6 0.1 4.6 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus CHD5 PF04420.14 KFQ91602.1 - 1.7 8.5 18.7 1.2 9.0 0.3 4.0 4 0 0 4 4 4 0 CHD5-like protein Pox_A_type_inc PF04508.12 KFQ91602.1 - 2.5 8.1 0.0 2.5 8.1 0.0 4.7 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Translin PF01997.16 KFQ91603.1 - 9.5e-62 208.6 0.2 1.2e-61 208.3 0.2 1.1 1 0 0 1 1 1 1 Translin family 2OG-FeII_Oxy_3 PF13640.6 KFQ91604.1 - 1.8e-21 76.8 0.0 3.1e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KFQ91604.1 - 9.4e-11 42.2 0.0 1.8e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SprT-like PF10263.9 KFQ91605.1 - 2.8e-21 75.5 0.0 5.8e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 SprT-like family Aminopep PF10023.9 KFQ91605.1 - 0.082 12.3 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative aminopeptidase DUF2484 PF10658.9 KFQ91606.1 - 0.085 13.2 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2484) Exo84_C PF16528.5 KFQ91607.1 - 9.6e-58 195.4 0.0 1.5e-57 194.7 0.0 1.3 1 0 0 1 1 1 1 Exocyst component 84 C-terminal Adeno_terminal PF02459.15 KFQ91607.1 - 0.0045 15.4 7.6 0.0077 14.7 7.6 1.3 1 0 0 1 1 1 1 Adenoviral DNA terminal protein Dor1 PF04124.12 KFQ91607.1 - 0.0062 15.3 1.6 0.022 13.4 0.2 2.3 2 0 0 2 2 2 1 Dor1-like family DUF2052 PF09747.9 KFQ91607.1 - 0.021 15.0 3.6 0.035 14.2 3.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) PH PF00169.29 KFQ91607.1 - 0.069 13.7 0.0 0.26 11.8 0.0 1.9 2 0 0 2 2 2 0 PH domain Ribosomal_60s PF00428.19 KFQ91607.1 - 1.3 9.6 7.4 3.3 8.3 7.4 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ras PF00071.22 KFQ91608.1 - 2.4e-26 92.3 0.0 2.9e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ91608.1 - 1.2e-06 28.7 0.0 3e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Lipase_GDSL_3 PF14606.6 KFQ91608.1 - 0.0019 18.4 0.0 0.0023 18.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SLBP_RNA_bind PF15247.6 KFQ91608.1 - 0.069 13.3 1.4 0.17 12.0 0.4 1.9 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain Abhydrolase_2 PF02230.16 KFQ91608.1 - 0.12 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Ras PF00071.22 KFQ91609.1 - 3.9e-59 198.9 0.2 4.4e-59 198.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ91609.1 - 2.7e-33 114.7 0.1 3.7e-33 114.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ91609.1 - 2.7e-14 53.0 0.1 3.4e-14 52.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFQ91609.1 - 5.1e-06 26.2 0.1 0.00035 20.2 0.1 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFQ91609.1 - 8.3e-05 22.7 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFQ91609.1 - 0.00071 19.0 0.0 0.00083 18.8 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFQ91609.1 - 0.0015 18.0 0.0 0.0025 17.3 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KFQ91609.1 - 0.0021 18.0 0.2 0.91 9.4 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 KFQ91609.1 - 0.0061 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KFQ91609.1 - 0.023 15.0 0.1 0.14 12.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KFQ91609.1 - 0.025 14.3 0.1 0.08 12.7 0.0 1.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KFQ91609.1 - 0.029 14.7 0.0 0.042 14.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 KFQ91609.1 - 0.037 13.4 0.1 0.074 12.4 0.1 1.5 1 0 0 1 1 1 0 KaiC ATP_bind_1 PF03029.17 KFQ91609.1 - 0.04 13.7 0.0 4 7.1 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 KFQ91609.1 - 0.053 13.4 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Septin PF00735.18 KFQ91609.1 - 0.072 12.4 0.0 0.096 11.9 0.0 1.2 1 0 0 1 1 1 0 Septin DUF2075 PF09848.9 KFQ91609.1 - 0.075 12.3 0.1 0.13 11.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 KFQ91609.1 - 0.078 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 KFQ91609.1 - 0.12 12.8 0.1 0.94 9.9 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CCSAP PF15748.5 KFQ91610.1 - 7.1e-53 180.4 24.1 7.8e-53 180.2 24.1 1.0 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated Actin PF00022.19 KFQ91611.1 - 2.3e-132 441.5 0.0 8.5e-132 439.6 0.0 1.7 1 1 0 1 1 1 1 Actin Nucleoporin_C PF03177.14 KFQ91613.1 - 2.4e-25 89.3 14.0 3.3e-24 85.6 14.0 2.6 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KFQ91613.1 - 6.8e-12 44.9 0.4 1.1e-11 44.1 0.4 1.2 1 0 0 1 1 1 1 Nup133 N terminal like DYW_deaminase PF14432.6 KFQ91613.1 - 0.077 12.9 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases ABC_membrane PF00664.23 KFQ91614.1 - 1.8e-59 201.7 5.0 2.5e-59 201.2 5.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFQ91614.1 - 2.2e-33 115.7 0.0 4.7e-33 114.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFQ91614.1 - 2.3e-07 30.5 0.1 5.5e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 KFQ91614.1 - 0.00059 20.3 0.2 0.009 16.4 0.2 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFQ91614.1 - 0.0012 19.2 0.3 0.0048 17.3 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KFQ91614.1 - 0.0023 17.6 0.1 0.005 16.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KFQ91614.1 - 0.0029 17.2 0.0 0.0072 15.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 KFQ91614.1 - 0.003 16.4 0.1 0.052 12.3 0.1 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 KFQ91614.1 - 0.0032 17.7 0.2 0.024 14.9 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KFQ91614.1 - 0.013 15.3 0.1 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 KFQ91614.1 - 0.014 15.4 0.2 0.096 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KFQ91614.1 - 0.02 14.6 0.1 0.078 12.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFQ91614.1 - 0.022 14.7 0.1 0.058 13.3 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 KFQ91614.1 - 0.064 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KFQ91614.1 - 0.1 12.8 0.0 0.37 11.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFQ91614.1 - 0.14 12.7 0.0 0.45 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KFQ91614.1 - 0.16 11.2 0.0 0.51 9.6 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.6 KFQ91614.1 - 0.18 11.5 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain WD40 PF00400.32 KFQ91615.1 - 1.5e-53 177.5 6.1 5.5e-10 39.7 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KFQ91615.1 - 8.1e-31 106.9 3.9 1.4e-30 106.2 3.9 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KFQ91615.1 - 1.4e-12 47.7 0.0 0.0033 17.7 0.0 4.5 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFQ91615.1 - 4.2e-05 22.4 0.4 0.51 8.9 0.1 3.4 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFQ91615.1 - 0.00073 18.6 0.0 0.17 10.8 0.0 3.4 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFQ91615.1 - 0.0013 18.2 0.0 2.2 7.5 0.0 3.2 1 1 0 2 2 2 2 WD40-like domain eIF2A PF08662.11 KFQ91615.1 - 0.0046 16.9 0.0 0.048 13.5 0.0 2.5 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KFQ91615.1 - 0.066 12.5 0.0 0.36 10.1 0.0 2.1 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal DDE_Tnp_1_7 PF13843.6 KFQ91616.1 - 9.6e-84 281.7 0.5 1.1e-83 281.5 0.5 1.0 1 0 0 1 1 1 1 Transposase IS4 HEPN PF05168.14 KFQ91616.1 - 0.046 13.9 0.0 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 HEPN domain DUF3510 PF12022.8 KFQ91617.1 - 1.2e-40 138.8 1.5 1.9e-40 138.1 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) COG2 PF06148.11 KFQ91617.1 - 2.4e-37 128.0 3.4 2.4e-37 128.0 3.4 3.3 4 1 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 KFQ91617.1 - 0.00011 22.2 0.6 0.0021 18.1 0.1 2.8 2 0 0 2 2 2 1 Vps51/Vps67 DUF1664 PF07889.12 KFQ91617.1 - 0.015 15.3 4.8 0.077 13.0 0.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF2451 PF10474.9 KFQ91617.1 - 0.042 13.6 0.2 8.1 6.2 0.0 2.6 1 1 0 2 2 2 0 Protein of unknown function C-terminus (DUF2451) COG5 PF10392.9 KFQ91617.1 - 0.3 11.3 6.9 0.9 9.7 0.4 3.3 3 1 0 3 3 3 0 Golgi transport complex subunit 5 DUF4795 PF16043.5 KFQ91617.1 - 1.2 8.6 5.2 1.9 8.0 1.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) Serpin PF00079.20 KFQ91618.1 - 1.5e-58 198.9 0.0 1.9e-58 198.6 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Peptidase_C2 PF00648.21 KFQ91619.1 - 1.7e-131 437.7 0.0 2.9e-131 436.9 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KFQ91619.1 - 3.8e-49 166.6 0.0 6.5e-49 165.8 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_1 PF00036.32 KFQ91619.1 - 1.1e-10 40.3 5.1 0.00012 21.3 0.1 4.1 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 KFQ91619.1 - 1.9e-10 39.8 2.4 0.00014 21.5 0.1 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KFQ91619.1 - 8.1e-09 35.2 1.3 1.5e-06 28.0 0.1 3.3 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.6 KFQ91619.1 - 0.00059 20.2 5.0 0.21 12.1 0.4 3.5 2 2 0 2 2 2 2 EF-hand domain pair Ndufs5 PF10200.9 KFQ91619.1 - 0.011 16.0 0.2 0.16 12.2 0.0 2.8 3 0 0 3 3 3 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa EF-hand_5 PF13202.6 KFQ91619.1 - 0.037 13.5 4.4 1.2 8.7 0.0 3.3 3 0 0 3 3 3 0 EF hand KAR9 PF08580.10 KFQ91620.1 - 2.4 6.6 8.6 2.6 6.5 8.6 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Arv1 PF04161.13 KFQ91621.1 - 1.2e-48 166.0 4.9 1.4e-48 165.8 4.9 1.0 1 0 0 1 1 1 1 Arv1-like family SLT_L PF14718.6 KFQ91621.1 - 0.13 12.4 0.1 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 Soluble lytic murein transglycosylase L domain SPRY PF00622.28 KFQ91622.1 - 4.9e-12 46.0 0.0 7.7e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 SPRY domain fn3 PF00041.21 KFQ91622.1 - 7.9e-09 35.7 0.0 1.7e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain zf-B_box PF00643.24 KFQ91622.1 - 9.6e-09 35.3 2.8 2.6e-08 33.9 2.8 1.8 1 0 0 1 1 1 1 B-box zinc finger PRY PF13765.6 KFQ91622.1 - 1.4e-05 24.6 0.1 3.4e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 SPRY-associated domain Laminin_G_3 PF13385.6 KFQ91622.1 - 0.011 15.9 0.4 0.034 14.3 0.1 2.0 2 0 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily zf-UBR PF02207.20 KFQ91622.1 - 0.039 14.1 2.2 0.12 12.6 2.2 1.9 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DUF1281 PF06924.11 KFQ91622.1 - 0.12 11.9 0.4 0.2 11.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) DUF4602 PF15375.6 KFQ91623.1 - 3e-20 72.9 12.8 3.3e-20 72.8 12.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4602) Acyltransferase PF01553.21 KFQ91624.1 - 2.9e-25 88.5 0.0 5.3e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase TBP PF00352.21 KFQ91625.1 - 7.2e-64 211.7 0.3 3.2e-32 110.3 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KFQ91625.1 - 0.00033 20.7 1.0 1.5 9.0 0.0 3.0 4 0 0 4 4 4 2 Domain of unknown function (DUF3378) Proteasome PF00227.26 KFQ91626.1 - 8.3e-39 133.0 0.1 1.1e-38 132.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Cytochrom_C1 PF02167.15 KFQ91626.1 - 0.0015 18.3 0.1 0.0021 17.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome C1 family EGF PF00008.27 KFQ91628.1 - 1.3e-40 137.3 152.8 1.1e-08 35.2 6.0 10.2 9 1 0 9 9 9 7 EGF-like domain hEGF PF12661.7 KFQ91628.1 - 5.9e-31 106.0 121.9 9.5e-07 29.2 10.6 10.8 10 0 0 10 10 10 6 Human growth factor-like EGF DSL PF01414.19 KFQ91628.1 - 1e-23 83.3 8.3 1e-23 83.3 8.3 7.8 6 3 2 8 8 8 3 Delta serrate ligand EGF_2 PF07974.13 KFQ91628.1 - 1.5e-05 25.2 172.3 0.0055 17.1 11.5 10.6 10 0 0 10 10 10 6 EGF-like domain EGF_CA PF07645.15 KFQ91628.1 - 2.2e-05 24.5 27.5 0.00014 22.0 10.0 10.2 5 2 5 10 10 10 5 Calcium-binding EGF domain EGF_3 PF12947.7 KFQ91628.1 - 0.00038 20.6 22.0 0.0022 18.1 9.7 10.1 8 2 1 9 9 9 4 EGF domain ECSCR PF15820.5 KFQ91628.1 - 0.028 14.3 0.1 0.028 14.3 0.1 1.7 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator DUF4209 PF13910.6 KFQ91629.1 - 8.2e-28 96.5 0.1 1.7e-23 82.6 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4209) Tctex-1 PF03645.13 KFQ91630.1 - 1.2e-22 80.1 0.8 1.4e-22 79.9 0.8 1.0 1 0 0 1 1 1 1 Tctex-1 family PHD PF00628.29 KFQ91631.1 - 5e-17 61.5 25.0 1.1e-08 34.8 10.5 2.4 1 1 1 2 2 2 2 PHD-finger PHD_4 PF16866.5 KFQ91631.1 - 0.0021 18.1 9.6 0.0021 18.1 9.6 3.2 1 1 1 2 2 2 1 PHD-finger PHD_2 PF13831.6 KFQ91631.1 - 0.014 15.0 4.7 0.014 15.0 4.7 2.7 2 1 0 2 2 2 0 PHD-finger Herpes_MCP PF03122.14 KFQ91631.1 - 0.036 11.6 0.2 0.047 11.1 0.2 1.0 1 0 0 1 1 1 0 Herpes virus major capsid protein Zf_RING PF16744.5 KFQ91631.1 - 4.4 7.5 22.0 3 8.0 9.4 3.2 1 1 1 2 2 2 0 KIAA1045 RING finger zf-PHD-like PF15446.6 KFQ91631.1 - 5.2 6.7 18.2 3.8 7.1 4.7 3.0 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain UPF0669 PF17065.5 KFQ91632.1 - 2.9e-109 362.9 0.3 3.2e-109 362.8 0.3 1.0 1 0 0 1 1 1 1 Putative cytokine, C6ORF120 ROS_MUCR PF05443.11 KFQ91634.1 - 0.074 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein TSP_C PF05735.12 KFQ91635.1 - 8.7e-70 234.7 1.8 1.3e-69 234.2 1.8 1.2 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.18 KFQ91635.1 - 1.5e-57 190.9 139.2 7.4e-12 44.7 15.4 10.4 8 2 2 10 10 10 8 Thrombospondin type 3 repeat TSP_1 PF00090.19 KFQ91635.1 - 2.5e-46 155.7 56.5 4.6e-17 62.0 8.5 4.9 4 0 0 4 4 4 3 Thrombospondin type 1 domain VWC PF00093.18 KFQ91635.1 - 4e-13 49.5 17.7 4e-13 49.5 17.7 6.0 5 1 1 6 6 6 1 von Willebrand factor type C domain EGF_3 PF12947.7 KFQ91635.1 - 2.5e-07 30.8 7.2 2.5e-07 30.8 7.2 5.9 6 0 0 6 6 6 2 EGF domain EGF_CA PF07645.15 KFQ91635.1 - 4.8e-06 26.7 1.7 4.8e-06 26.7 1.7 5.5 4 0 0 4 4 4 3 Calcium-binding EGF domain Laminin_G_3 PF13385.6 KFQ91635.1 - 0.0026 17.9 1.1 0.33 11.1 0.0 2.3 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 KFQ91635.1 - 0.0031 17.8 8.3 0.0031 17.8 8.3 4.9 4 0 0 4 4 4 1 EGF-like domain cEGF PF12662.7 KFQ91635.1 - 0.011 15.6 0.5 0.011 15.6 0.5 5.1 5 0 0 5 5 5 0 Complement Clr-like EGF-like Laminin_G_2 PF02210.24 KFQ91635.1 - 0.13 12.9 0.0 0.24 12.0 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain Thyroglobulin_1 PF00086.18 KFQ91636.1 - 1.2e-37 127.3 18.8 3e-19 68.4 4.5 2.9 2 0 0 2 2 2 2 Thyroglobulin type-1 repeat Thyroglob_assoc PF16597.5 KFQ91636.1 - 3e-24 85.1 2.1 6.3e-24 84.1 2.1 1.6 1 0 0 1 1 1 1 Thyroglobulin_1 repeat associated disordered domain SPARC_Ca_bdg PF10591.9 KFQ91636.1 - 1.1e-11 45.1 0.1 3.1e-11 43.6 0.1 1.8 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_2 PF07648.15 KFQ91636.1 - 1.8e-07 31.2 4.2 1.8e-07 31.2 4.2 2.2 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.6 KFQ91636.1 - 1e-05 25.9 0.1 0.00013 22.3 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFQ91636.1 - 5.9e-05 22.3 0.2 1.4 8.7 0.0 3.7 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 KFQ91636.1 - 0.00014 21.5 0.3 1.5 9.0 0.1 3.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 KFQ91636.1 - 0.018 14.5 2.0 0.13 11.9 0.0 3.2 4 0 0 4 4 4 0 EF hand Sulfotransfer_1 PF00685.27 KFQ91637.1 - 2e-25 89.8 0.6 2.2e-25 89.7 0.6 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_1 PF00685.27 KFQ91638.1 - 7.1e-41 140.5 0.8 8.1e-41 140.2 0.8 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFQ91638.1 - 3.8e-05 24.2 0.0 6.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family Dapper PF15268.6 KFQ91640.1 - 7.9e-237 789.1 39.3 8.9e-237 788.9 39.3 1.0 1 0 0 1 1 1 1 Dapper FERM_M PF00373.18 KFQ91641.1 - 2.9e-21 76.1 0.5 7.1e-21 74.8 0.5 1.7 1 0 0 1 1 1 1 FERM central domain FERM_C PF09380.10 KFQ91641.1 - 4e-16 59.2 0.0 1.2e-15 57.7 0.0 1.8 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KFQ91641.1 - 3e-12 46.3 0.0 6.6e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 FERM N-terminal domain Kinesin PF00225.23 KFQ91642.1 - 1.5e-83 280.5 0.2 4.9e-48 163.8 0.0 2.2 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KFQ91642.1 - 1.2e-40 138.8 0.0 3e-40 137.6 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding EBP50_C PF09007.11 KFQ91642.1 - 0.17 12.9 7.6 2.4 9.1 0.4 2.5 2 0 0 2 2 2 0 EBP50, C-terminal Tup_N PF08581.10 KFQ91642.1 - 1.4 9.2 6.7 1.6 9.1 4.6 2.0 1 1 0 1 1 1 0 Tup N-terminal RA PF00788.23 KFQ91643.1 - 1.3e-46 157.2 0.0 2.1e-23 82.7 0.0 3.1 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain DIL PF01843.19 KFQ91643.1 - 1.9e-30 105.2 1.6 1.9e-30 105.2 1.6 2.1 2 0 0 2 2 2 1 DIL domain PDZ PF00595.24 KFQ91643.1 - 4.7e-17 62.1 0.6 1.1e-16 60.9 0.6 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFQ91643.1 - 2.5e-08 33.6 0.4 5.4e-08 32.6 0.4 1.6 1 0 0 1 1 1 1 PDZ domain FHA PF00498.26 KFQ91643.1 - 1.3e-06 28.6 0.0 3.3e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 FHA domain PDZ_2 PF13180.6 KFQ91643.1 - 5.1e-05 23.5 0.4 0.00018 21.8 0.4 1.9 1 0 0 1 1 1 1 PDZ domain Yop-YscD_cpl PF16697.5 KFQ91643.1 - 0.008 16.5 0.0 0.027 14.8 0.0 2.0 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF4477 PF14780.6 KFQ91643.1 - 0.08 12.6 0.1 0.24 11.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) UNC-93 PF05978.16 KFQ91644.1 - 2.4e-11 43.6 9.6 2.4e-11 43.6 9.6 3.5 2 2 1 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KFQ91644.1 - 2.4e-05 23.5 34.2 0.003 16.5 7.4 3.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Tcp10_C PF07202.13 KFQ91645.1 - 1.6e-86 288.8 6.7 1.8e-86 288.6 6.7 1.0 1 0 0 1 1 1 1 T-complex protein 10 C-terminus DUF4176 PF13780.6 KFQ91645.1 - 0.0081 16.2 0.2 0.12 12.4 0.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4176) GSHPx PF00255.19 KFQ91645.1 - 0.045 13.3 0.1 0.098 12.2 0.1 1.6 1 1 0 1 1 1 0 Glutathione peroxidase Big_11 PF18200.1 KFQ91645.1 - 0.077 12.9 1.6 1.2 9.1 0.3 2.8 1 1 2 3 3 3 0 Bacterial Ig-like domain potato_inhibit PF00280.18 KFQ91645.1 - 0.19 12.4 1.3 32 5.3 0.0 3.4 3 1 1 4 4 4 0 Potato inhibitor I family TBK1_CCD1 PF18394.1 KFQ91646.1 - 0.0035 16.9 0.2 0.004 16.8 0.2 1.1 1 0 0 1 1 1 1 TANK-binding kinase 1 coiled-coil domain 1 Ribonuclease_T2 PF00445.18 KFQ91647.1 - 3e-56 190.5 8.2 3.6e-56 190.3 8.2 1.0 1 0 0 1 1 1 1 Ribonuclease T2 family Pkinase PF00069.25 KFQ91649.1 - 1.3e-147 490.2 0.0 7e-75 251.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ91649.1 - 3.4e-77 259.2 0.0 7e-41 140.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFQ91649.1 - 1.9e-13 50.4 0.0 5.3e-06 26.0 0.0 2.6 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 KFQ91649.1 - 3.7e-10 39.5 0.0 8.6e-06 25.2 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.24 KFQ91649.1 - 6.9e-08 33.1 1.6 2e-07 31.6 1.6 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 KFQ91649.1 - 4.5e-07 29.0 0.0 0.006 15.4 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 KFQ91649.1 - 5.8e-06 26.4 0.0 0.21 11.5 0.0 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family FTA2 PF13095.6 KFQ91649.1 - 2.9e-05 23.8 0.1 0.88 9.2 0.0 3.3 3 0 0 3 3 3 3 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KFQ91649.1 - 5.5e-05 22.3 0.1 0.029 13.3 0.1 2.2 2 0 0 2 2 2 2 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 KFQ91649.1 - 0.00092 18.8 0.0 0.22 11.0 0.0 2.5 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL RIO1 PF01163.22 KFQ91649.1 - 0.0052 16.4 0.3 0.35 10.5 0.0 2.6 3 0 0 3 3 3 1 RIO1 family MPC PF03650.13 KFQ91651.1 - 1.5e-31 108.8 0.1 1.8e-31 108.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Got1 PF04178.12 KFQ91652.1 - 8.4e-36 122.8 17.6 1.7e-35 121.9 16.9 1.7 1 1 1 2 2 2 2 Got1/Sft2-like family DUF4064 PF13273.6 KFQ91652.1 - 0.025 14.9 10.1 2.1 8.7 9.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Bac_export_2 PF01312.19 KFQ91652.1 - 0.18 11.0 6.2 0.94 8.6 6.2 1.8 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family FtsX PF02687.21 KFQ91652.1 - 9 6.8 13.7 57 4.3 13.7 2.0 1 1 0 1 1 1 0 FtsX-like permease family T-box PF00907.22 KFQ91653.1 - 2e-25 90.1 0.2 3e-25 89.6 0.2 1.3 1 0 0 1 1 1 1 T-box PDEase_I PF00233.19 KFQ91654.1 - 5.4e-72 242.3 0.3 1.4e-70 237.7 0.1 2.2 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 KFQ91654.1 - 2.2e-29 102.8 0.0 1.6e-18 67.6 0.0 2.4 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 KFQ91654.1 - 6.3e-19 68.6 0.0 8.2e-09 35.9 0.0 2.3 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 KFQ91654.1 - 5.4e-09 36.5 0.0 1.2e-05 25.6 0.0 2.6 2 0 0 2 2 2 2 GAF domain SpoVT_C PF15714.5 KFQ91654.1 - 1.4e-05 25.1 0.0 0.003 17.6 0.0 2.6 2 0 0 2 2 2 1 Stage V sporulation protein T C-terminal, transcription factor HD PF01966.22 KFQ91654.1 - 0.055 13.7 0.2 0.12 12.6 0.2 1.6 1 0 0 1 1 1 0 HD domain H_kinase_N PF12282.8 KFQ91654.1 - 0.079 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Signal transduction histidine kinase DUF4748 PF15932.5 KFQ91654.1 - 0.17 11.6 0.0 0.44 10.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Quaking_NLS PF16551.5 KFQ91655.1 - 1.3e-16 60.0 5.7 2.2e-16 59.2 5.7 1.4 1 0 0 1 1 1 1 Putative nuclear localisation signal of quaking KH_1 PF00013.29 KFQ91655.1 - 1.7e-06 27.7 0.0 4.3e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 KH domain STAR_dimer PF16544.5 KFQ91655.1 - 0.00031 20.3 0.1 0.00059 19.3 0.1 1.5 1 0 0 1 1 1 1 Homodimerisation region of STAR domain protein zf-RING_14 PF17978.1 KFQ91656.1 - 9.2e-44 147.8 7.3 9.2e-44 147.8 7.3 2.0 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_12 PF17976.1 KFQ91656.1 - 1.6e-39 134.0 5.0 1.6e-39 134.0 5.0 2.7 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain IBR PF01485.21 KFQ91656.1 - 1.6e-13 50.6 19.7 4e-08 33.4 11.2 4.8 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain Acyltransf_C PF16076.5 KFQ91658.1 - 9.3e-27 92.9 0.2 1.8e-26 92.1 0.2 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 KFQ91658.1 - 2e-15 56.6 0.0 3.5e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Kringle PF00051.18 KFQ91660.1 - 8.3e-147 477.9 68.5 5.7e-31 106.7 8.5 5.5 5 0 0 5 5 5 5 Kringle domain Trypsin PF00089.26 KFQ91660.1 - 4e-49 167.4 0.1 9.2e-49 166.2 0.1 1.6 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFQ91660.1 - 1.1e-10 41.8 0.2 2.1e-10 41.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) PAN_1 PF00024.26 KFQ91660.1 - 1.5e-07 31.3 1.5 1.5e-07 31.3 1.5 2.7 2 0 0 2 2 2 1 PAN domain DUF3719 PF12516.8 KFQ91660.1 - 8.8 6.1 9.4 1e+02 2.7 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF3719) Kringle PF00051.18 KFQ91661.1 - 1.7e-149 486.4 71.7 3e-31 107.6 8.1 5.4 5 0 0 5 5 5 5 Kringle domain Trypsin PF00089.26 KFQ91661.1 - 4.2e-63 213.1 0.1 7.2e-63 212.4 0.1 1.4 1 0 0 1 1 1 1 Trypsin PAN_1 PF00024.26 KFQ91661.1 - 7.2e-11 41.9 2.1 7.2e-11 41.9 2.1 2.3 2 0 0 2 2 2 1 PAN domain Trypsin_2 PF13365.6 KFQ91661.1 - 1.3e-09 39.1 0.0 2.6e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFQ91661.1 - 1.2e-07 32.1 0.0 2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) KduI PF04962.12 KFQ91661.1 - 0.036 13.4 4.8 3 7.1 0.1 3.0 3 0 0 3 3 3 0 KduI/IolB family Sugar_tr PF00083.24 KFQ91662.1 - 2.9e-29 102.2 15.5 2.9e-29 102.2 15.5 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KFQ91662.1 - 1e-27 97.0 36.4 8.2e-21 74.3 14.8 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily PDZ PF00595.24 KFQ91663.1 - 0.00035 20.8 0.1 0.0028 18.0 0.1 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KFQ91663.1 - 0.00039 20.7 0.3 0.0007 19.9 0.3 1.4 1 1 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFQ91663.1 - 0.0013 18.5 0.3 0.0045 16.8 0.3 1.8 1 1 0 1 1 1 1 PDZ domain DUF4515 PF14988.6 KFQ91664.1 - 3.4e-15 56.4 22.1 3.4e-15 56.4 22.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4515) FKBP_N PF01346.18 KFQ91664.1 - 0.028 15.4 4.0 0.028 15.4 4.0 2.9 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase zf-NPL4 PF05020.15 KFQ91664.1 - 0.12 12.5 4.3 0.092 12.9 0.4 2.1 2 0 0 2 2 2 0 NPL4 family, putative zinc binding region ENT PF03735.14 KFQ91664.1 - 0.13 12.3 0.6 0.13 12.3 0.6 2.8 3 0 0 3 3 3 0 ENT domain LRR_8 PF13855.6 KFQ91665.1 - 2.8e-33 113.5 47.5 4.4e-08 32.8 4.4 6.3 3 2 2 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFQ91665.1 - 3.2e-29 100.5 48.1 6.9e-05 23.1 0.9 8.7 5 2 4 9 9 9 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFQ91665.1 - 2.9e-07 30.2 22.5 0.00021 20.9 3.7 5.0 1 1 4 6 6 6 4 Leucine-rich repeat LRR_1 PF00560.33 KFQ91665.1 - 0.011 16.2 43.9 15 6.6 0.2 12.3 11 3 1 12 12 12 0 Leucine Rich Repeat H-kinase_dim PF02895.14 KFQ91665.1 - 0.89 10.0 4.3 2.6 8.5 0.3 3.5 3 1 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain CSTF_C PF14304.6 KFQ91665.1 - 1.5 8.4 10.7 7.1 6.3 0.1 5.0 5 0 0 5 5 5 0 Transcription termination and cleavage factor C-terminal RRM_1 PF00076.22 KFQ91666.1 - 5.6e-44 147.8 0.1 1e-18 66.9 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFQ91666.1 - 0.00068 19.7 2.4 0.48 10.6 0.0 3.5 4 1 0 4 4 4 2 RNA recognition motif OB_RNB PF08206.11 KFQ91666.1 - 0.058 13.1 0.1 5.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain RRM_3 PF08777.11 KFQ91666.1 - 0.097 12.7 0.0 8 6.6 0.0 2.8 2 0 0 2 2 2 0 RNA binding motif Pkinase PF00069.25 KFQ91667.1 - 5.1e-22 78.5 0.1 9.1e-22 77.7 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ91667.1 - 2.8e-21 76.0 0.0 4.2e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Plectin PF00681.20 KFQ91668.1 - 9.3e-49 163.0 0.0 2.7e-18 65.5 0.0 4.9 4 1 1 5 5 5 4 Plectin repeat Plectin PF00681.20 KFQ91670.1 - 1.4e-252 815.3 9.5 7.2e-21 73.8 0.0 23.6 20 4 4 24 24 24 18 Plectin repeat HTH_10 PF04967.12 KFQ91670.1 - 1.1e-05 25.2 1.5 29 4.6 0.0 6.5 6 0 0 6 6 6 2 HTH DNA binding domain TA0956 PF11513.8 KFQ91670.1 - 0.012 15.9 1.0 0.088 13.0 0.2 2.9 3 0 0 3 3 3 0 Thermoplasma acidophilum protein TA0956 Retrotran_gag_2 PF14223.6 KFQ91670.1 - 0.049 13.3 2.6 4.9 6.8 0.1 3.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type SANTA PF09133.10 KFQ91670.1 - 0.32 11.5 1.5 17 5.9 0.0 3.4 3 0 0 3 3 3 0 SANTA (SANT Associated) Plectin PF00681.20 KFQ91671.1 - 1.3e-259 837.8 0.7 7e-21 73.8 0.0 23.4 18 5 7 25 25 25 20 Plectin repeat HTH_10 PF04967.12 KFQ91671.1 - 5.5e-06 26.1 0.2 5.4 6.9 0.0 5.9 6 0 0 6 6 6 3 HTH DNA binding domain DUF1722 PF08349.11 KFQ91671.1 - 0.0083 16.4 1.7 6.2 7.1 0.1 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1722) Toprim_Crpt PF13342.6 KFQ91671.1 - 0.029 14.3 0.2 9.9 6.2 0.0 3.4 3 0 0 3 3 3 0 C-terminal repeat of topoisomerase BESS PF02944.20 KFQ91672.1 - 0.082 12.7 1.2 0.2 11.5 1.2 1.7 1 0 0 1 1 1 0 BESS motif Spectrin PF00435.21 KFQ91673.1 - 0.00059 20.3 6.2 0.0047 17.4 0.1 3.1 3 0 0 3 3 3 2 Spectrin repeat BAR PF03114.18 KFQ91674.1 - 2.6e-50 171.3 6.6 2.6e-50 171.3 6.6 1.6 2 0 0 2 2 2 1 BAR domain SH3_9 PF14604.6 KFQ91674.1 - 6.7e-09 35.5 0.0 1.6e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFQ91674.1 - 1.6e-06 27.6 0.1 1.8e-05 24.3 0.1 2.3 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFQ91674.1 - 0.0003 20.4 0.0 0.00061 19.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 KFQ91674.1 - 0.0008 19.2 2.2 0.0017 18.1 2.1 1.5 1 1 0 1 1 1 1 BAR domain of APPL family Arfaptin PF06456.13 KFQ91674.1 - 0.0068 16.0 3.4 0.011 15.3 3.4 1.4 1 0 0 1 1 1 1 Arfaptin-like domain EzrA PF06160.12 KFQ91674.1 - 0.015 13.5 4.1 0.7 8.0 0.3 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA HD_3 PF13023.6 KFQ91674.1 - 0.042 13.8 0.2 0.042 13.8 0.2 2.4 2 1 1 3 3 3 0 HD domain OmpH PF03938.14 KFQ91674.1 - 0.28 11.5 7.4 0.93 9.8 0.2 2.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Jnk-SapK_ap_N PF09744.9 KFQ91674.1 - 0.73 10.0 9.1 0.23 11.7 2.2 2.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Occludin_ELL PF07303.13 KFQ91674.1 - 4.9 7.9 6.1 2.7 8.8 1.0 2.5 2 0 0 2 2 2 0 Occludin homology domain C1-set PF07654.15 KFQ91675.1 - 4.1e-12 46.3 1.5 7.1e-12 45.6 1.5 1.4 1 0 0 1 1 1 1 Immunoglobulin C1-set domain V-set PF07686.17 KFQ91675.1 - 3.4e-11 43.3 0.1 3.4e-11 43.3 0.1 2.0 2 1 0 2 2 2 1 Immunoglobulin V-set domain ig PF00047.25 KFQ91675.1 - 4.5e-05 23.6 1.6 0.14 12.4 1.2 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 KFQ91675.1 - 0.00015 22.3 1.1 0.21 12.2 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFQ91675.1 - 0.093 12.8 0.0 0.093 12.8 0.0 2.3 2 1 0 2 2 2 0 Immunoglobulin I-set domain Integrin_alpha2 PF08441.12 KFQ91677.1 - 9.5e-92 308.3 0.1 1.7e-91 307.5 0.0 1.3 2 0 0 2 2 2 1 Integrin alpha FG-GAP PF01839.23 KFQ91677.1 - 3.6e-24 84.5 18.9 8.2e-11 41.8 0.0 5.0 5 0 0 5 5 5 4 FG-GAP repeat VCBS PF13517.6 KFQ91677.1 - 1.4e-11 44.7 15.5 8.6e-09 35.9 2.7 3.1 1 1 2 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.20 KFQ91677.1 - 0.00088 19.1 0.2 0.0027 17.5 0.2 1.9 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region FG-GAP_2 PF14312.6 KFQ91677.1 - 0.021 15.1 1.0 0.021 15.1 1.0 4.5 5 0 0 5 5 5 0 FG-GAP repeat Neuro_bHLH PF12533.8 KFQ91678.1 - 2.8e-41 141.6 3.5 5.8e-41 140.6 3.5 1.6 1 0 0 1 1 1 1 Neuronal helix-loop-helix transcription factor HLH PF00010.26 KFQ91678.1 - 6.6e-16 58.0 0.7 6.6e-16 58.0 0.7 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain CDC45 PF02724.14 KFQ91678.1 - 6.9 4.8 7.7 8.7 4.5 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Collagen PF01391.18 KFQ91680.1 - 1.2e-40 137.0 125.0 3.9e-09 36.1 26.7 5.3 1 1 2 3 3 3 2 Collagen triple helix repeat (20 copies) SRCR PF00530.18 KFQ91680.1 - 4.2e-28 97.8 1.9 7e-28 97.1 1.9 1.3 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFQ91680.1 - 1.1e-05 25.9 0.2 2.4e-05 24.8 0.2 1.5 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain MHC2-interact PF09307.10 KFQ91680.1 - 0.034 14.1 0.1 0.064 13.3 0.1 1.4 1 0 0 1 1 1 0 CLIP, MHC2 interacting C1q PF00386.21 KFQ91681.1 - 6.1e-13 49.1 0.0 6.4e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 C1q domain TNF PF00229.18 KFQ91681.1 - 0.025 14.5 0.0 0.026 14.5 0.0 1.0 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family F420_oxidored PF03807.17 KFQ91682.1 - 7.9e-16 58.4 0.1 3.2e-15 56.5 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Ferric_reduct PF01794.19 KFQ91682.1 - 2.4e-13 50.3 7.0 5.5e-13 49.1 3.9 2.3 1 1 1 2 2 2 2 Ferric reductase like transmembrane component NAD_binding_2 PF03446.15 KFQ91682.1 - 0.00083 19.6 0.0 0.0025 18.0 0.0 1.7 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KFQ91682.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 KFQ91682.1 - 0.095 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Malt_amylase_C PF16657.5 KFQ91682.1 - 0.11 12.6 0.0 9.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Maltogenic Amylase, C-terminal domain Shikimate_DH PF01488.20 KFQ91682.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF2340 PF10209.9 KFQ91683.1 - 2.4e-44 150.7 0.0 2.6e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) DUF5049 PF16468.5 KFQ91683.1 - 0.17 11.8 0.7 3 7.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5049) TMEM37 PF15108.6 KFQ91684.1 - 2.4e-91 304.5 14.1 2.7e-91 304.4 14.1 1.0 1 0 0 1 1 1 1 Voltage-dependent calcium channel gamma-like subunit protein family 7tm_2 PF00002.24 KFQ91685.1 - 9.9e-91 303.4 17.6 1.3e-90 303.0 17.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFQ91685.1 - 2.8e-20 72.3 4.9 2.8e-20 72.3 4.9 1.8 2 0 0 2 2 2 1 Hormone receptor domain Insulin_TMD PF17870.1 KFQ91685.1 - 0.089 12.9 0.4 0.3 11.2 0.4 1.9 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment PapD-like PF14874.6 KFQ91686.1 - 6.3e-06 26.3 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Flagellar-associated PapD-like TMEM131_like PF12371.8 KFQ91686.1 - 0.00042 20.5 0.0 0.0008 19.6 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein 131-like ASH PF15780.5 KFQ91686.1 - 0.0032 17.7 0.0 0.0075 16.5 0.0 1.6 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin SMP_LBD PF17047.5 KFQ91688.1 - 7.5e-67 224.3 0.2 2.8e-66 222.4 0.4 1.9 2 0 0 2 2 2 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 KFQ91688.1 - 4.4e-51 171.5 2.1 1.2e-21 76.9 0.0 3.6 3 1 0 3 3 3 3 C2 domain cPLA2_C2 PF18695.1 KFQ91688.1 - 0.28 11.2 1.7 0.43 10.6 0.2 2.1 2 0 0 2 2 2 0 Cytosolic phospholipases A2 C2-domain AAA_24 PF13479.6 KFQ91689.1 - 0.0065 16.2 2.1 1.9 8.1 1.8 2.5 2 0 0 2 2 2 2 AAA domain CoA_transf_3 PF02515.17 KFQ91689.1 - 0.41 9.7 3.5 0.82 8.7 3.4 1.6 2 0 0 2 2 2 0 CoA-transferase family III TMCO5 PF14992.6 KFQ91689.1 - 0.79 9.2 41.7 0.015 14.9 21.1 2.4 1 1 1 2 2 2 0 TMCO5 family FAIM1 PF06905.13 KFQ91690.1 - 2.3e-88 294.4 3.3 2.6e-88 294.2 3.3 1.0 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) DUF3748 PF12566.8 KFQ91690.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) CBM-like PF14683.6 KFQ91690.1 - 0.018 14.9 0.1 0.038 13.9 0.1 1.5 1 1 0 1 1 1 0 Polysaccharide lyase family 4, domain III GP88 PF17338.2 KFQ91690.1 - 0.042 13.3 0.0 0.065 12.7 0.0 1.3 1 1 0 1 1 1 0 Gene product 88 MipZ PF09140.11 KFQ91690.1 - 0.082 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ Macro PF01661.21 KFQ91691.1 - 1.8e-38 131.2 0.1 4.2e-28 97.7 0.1 2.9 3 0 0 3 3 3 2 Macro domain PARP PF00644.20 KFQ91691.1 - 9.2e-07 28.6 0.1 4.4e-06 26.4 0.1 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain DTC PF18102.1 KFQ91692.1 - 1.3e-63 213.0 0.2 2.4e-63 212.2 0.2 1.5 1 0 0 1 1 1 1 Deltex C-terminal domain zf-C3HC4_2 PF13923.6 KFQ91692.1 - 3.9e-11 42.6 10.8 7.3e-11 41.7 10.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ91692.1 - 2.2e-09 37.5 9.9 4.7e-09 36.4 9.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFQ91692.1 - 2.9e-08 33.4 8.4 5.6e-08 32.5 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ91692.1 - 4.6e-07 29.6 13.4 9.8e-07 28.5 13.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFQ91692.1 - 4.6e-07 29.7 4.7 4.7e-07 29.7 2.9 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFQ91692.1 - 8.6e-07 28.8 11.0 1.8e-06 27.8 11.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFQ91692.1 - 6.6e-05 23.1 6.2 6.6e-05 23.1 6.2 2.2 2 0 0 2 2 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFQ91692.1 - 0.00016 21.4 9.8 0.0016 18.3 10.1 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 KH_1 PF00013.29 KFQ91692.1 - 0.0053 16.6 0.0 0.11 12.3 0.0 2.6 2 0 0 2 2 2 1 KH domain zf-C3HC4_4 PF15227.6 KFQ91692.1 - 0.0058 16.8 9.4 0.014 15.5 9.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KFQ91692.1 - 0.0074 16.1 3.5 0.016 15.1 3.5 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Siva PF05458.12 KFQ91692.1 - 0.01 15.5 2.5 0.019 14.7 2.5 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-RING_10 PF16685.5 KFQ91692.1 - 0.013 15.7 5.7 0.04 14.1 5.7 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KFQ91692.1 - 0.015 15.1 8.4 0.044 13.6 8.4 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 KFQ91692.1 - 0.029 14.2 7.3 0.088 12.6 7.3 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 KFQ91692.1 - 0.037 14.1 2.0 0.12 12.4 2.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Glyco_hydro_56 PF01630.18 KFQ91692.1 - 0.037 13.0 0.0 0.085 11.8 0.0 1.5 1 0 0 1 1 1 0 Hyaluronidase zf-RING_11 PF17123.5 KFQ91692.1 - 0.11 12.2 5.8 0.28 10.9 5.8 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-UDP PF14569.6 KFQ91692.1 - 0.12 12.6 5.8 0.75 10.0 5.5 2.4 2 0 0 2 2 2 0 Zinc-binding RING-finger ChaB PF06150.12 KFQ91692.1 - 0.15 12.7 0.1 3.6 8.2 0.0 2.5 2 0 0 2 2 2 0 ChaB DZR PF12773.7 KFQ91692.1 - 0.59 10.2 8.4 1.6 8.8 8.4 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4_5 PF17121.5 KFQ91692.1 - 3.6 7.6 11.9 17 5.4 11.9 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRM_occluded PF16842.5 KFQ91693.1 - 1.2e-05 25.1 0.7 0.019 14.8 0.0 2.1 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_occluded PF16842.5 KFQ91694.1 - 0.00031 20.5 0.0 0.0006 19.6 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif BOP1NT PF08145.12 KFQ91694.1 - 0.06 13.3 0.0 0.072 13.0 0.0 1.1 1 0 0 1 1 1 0 BOP1NT (NUC169) domain WWE PF02825.20 KFQ91695.1 - 1.8e-06 28.4 0.0 7.5e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 WWE domain YqgF PF14639.6 KFQ91695.1 - 0.0083 15.9 1.1 0.0099 15.7 0.2 1.7 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 LSM PF01423.22 KFQ91695.1 - 0.031 14.0 0.7 0.086 12.5 0.1 2.0 2 1 0 2 2 2 0 LSM domain Arylsulfotran_N PF17425.2 KFQ91695.1 - 0.076 13.1 0.2 0.25 11.4 0.1 1.9 1 1 0 1 1 1 0 Arylsulfotransferase Ig-like domain FidL_like PF15941.5 KFQ91695.1 - 0.45 11.0 2.9 13 6.3 0.0 2.9 2 1 1 3 3 3 0 FidL-like putative membrane protein Peptidase_M8 PF01457.16 KFQ91696.1 - 8.2e-47 160.1 14.3 2.6e-31 108.9 0.0 3.9 2 1 1 3 3 3 3 Leishmanolysin NAD_Gly3P_dh_C PF07479.14 KFQ91697.1 - 3.4e-50 170.0 0.6 1e-49 168.4 0.2 2.0 3 0 0 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KFQ91697.1 - 3.3e-46 157.1 0.1 9.4e-46 155.6 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF643 PF04867.12 KFQ91697.1 - 0.024 15.2 0.2 0.095 13.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF643) GerD PF17898.1 KFQ91697.1 - 0.026 14.5 0.1 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 Spore germination GerD central core domain Oxysterol_BP PF01237.18 KFQ91698.1 - 4.2e-83 279.2 3.6 2.5e-81 273.4 3.6 2.2 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 KFQ91698.1 - 2.8e-12 47.1 0.0 5.5e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFQ91698.1 - 1.5e-08 34.8 0.0 3.4e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 KFQ91698.1 - 3.2e-05 24.2 0.0 7.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 KFQ91698.1 - 0.0051 17.2 0.1 0.016 15.5 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 KFQ91698.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 KFQ91698.1 - 0.62 10.5 3.2 1.5 9.3 0.3 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain PX PF00787.24 KFQ91699.1 - 2.1e-23 82.4 0.1 5.1e-23 81.2 0.1 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KFQ91699.1 - 1.3e-05 24.9 10.9 0.003 17.1 10.9 2.2 1 1 0 1 1 1 1 Vps5 C terminal like FlgM PF04316.13 KFQ91699.1 - 0.065 13.6 0.2 0.2 12.1 0.2 1.9 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM Indigoidine_A PF04227.12 KFQ91699.1 - 0.082 12.3 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Indigoidine synthase A like protein Med9 PF07544.13 KFQ91699.1 - 0.93 9.6 4.1 4.2 7.5 4.1 2.2 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 zf-H2C2_2 PF13465.6 KFQ91700.1 - 1.7e-22 78.8 22.4 4.2e-07 30.1 0.3 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ91700.1 - 2.7e-12 46.4 37.8 0.00032 21.0 4.0 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ91700.1 - 9.5e-10 38.5 33.8 0.025 15.4 1.0 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger RBFA PF02033.18 KFQ91700.1 - 0.044 14.3 0.2 0.11 12.9 0.2 1.7 1 0 0 1 1 1 0 Ribosome-binding factor A zf-C2H2_jaz PF12171.8 KFQ91700.1 - 0.38 11.1 15.3 3.1 8.2 2.2 3.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DNA_RNApol_7kD PF03604.13 KFQ91700.1 - 0.39 10.4 1.7 1.2 8.8 0.3 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.7 KFQ91700.1 - 0.8 9.8 7.6 7.4 6.7 1.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 KFQ91700.1 - 4.2 8.2 9.4 20 6.0 1.5 2.7 1 1 1 2 2 2 0 zinc-ribbon family zf-MYST PF17772.1 KFQ91700.1 - 8.1 6.1 16.5 0.049 13.2 3.3 2.9 2 1 1 3 3 3 0 MYST family zinc finger domain AA_permease PF00324.21 KFQ91701.1 - 4.6e-43 147.5 35.6 4.6e-43 147.5 35.6 2.0 2 0 0 2 2 2 1 Amino acid permease EGF_CA PF07645.15 KFQ91702.1 - 3.9e-08 33.4 3.8 3.9e-08 33.4 3.8 4.4 3 1 2 5 5 5 2 Calcium-binding EGF domain EGF PF00008.27 KFQ91702.1 - 2.2e-05 24.6 4.6 2.2e-05 24.6 4.6 3.5 3 1 0 3 3 3 2 EGF-like domain hEGF PF12661.7 KFQ91702.1 - 0.00018 22.0 11.3 0.0025 18.4 1.8 3.8 3 0 0 3 3 3 2 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 KFQ91702.1 - 0.00019 21.4 23.8 0.00033 20.6 7.4 3.5 2 1 1 3 3 3 1 MSP1 EGF domain 1 EGF_3 PF12947.7 KFQ91702.1 - 0.00021 21.4 22.8 0.0059 16.8 6.1 3.3 2 1 1 3 3 3 2 EGF domain Orthoreo_P10 PF07204.11 KFQ91702.1 - 0.012 15.5 0.3 0.026 14.5 0.3 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 EB PF01683.18 KFQ91702.1 - 0.03 14.6 27.0 0.19 12.0 7.6 3.4 2 1 1 3 3 3 0 EB module FXa_inhibition PF14670.6 KFQ91702.1 - 0.039 14.2 8.0 0.039 14.2 8.0 4.1 2 1 1 3 3 3 0 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFQ91702.1 - 3.3 7.7 24.1 0.69 9.9 2.4 4.7 4 0 0 4 4 4 0 Complement Clr-like EGF-like Integrin_beta PF00362.18 KFQ91704.1 - 8e-110 366.3 0.0 1.2e-109 365.8 0.0 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_B_tail PF07965.12 KFQ91704.1 - 8.7e-18 64.6 5.6 8.7e-18 64.6 5.6 4.5 3 1 2 5 5 5 1 Integrin beta tail domain Integrin_b_cyt PF08725.11 KFQ91704.1 - 6.1e-17 61.0 0.2 6.1e-17 61.0 0.2 1.9 2 0 0 2 2 2 1 Integrin beta cytoplasmic domain PSI_integrin PF17205.3 KFQ91704.1 - 9.5e-14 50.9 8.2 9.5e-14 50.9 8.2 4.5 4 0 0 4 4 4 1 Integrin plexin domain I-EGF_1 PF18372.1 KFQ91704.1 - 5.4e-10 39.2 8.8 5.4e-10 39.2 8.8 6.1 6 0 0 6 6 6 3 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 KFQ91704.1 - 6.5e-09 36.0 97.7 0.00024 21.4 15.9 5.9 5 1 0 5 5 5 4 EGF-like domain DUF2975 PF11188.8 KFQ91704.1 - 0.17 11.7 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) RVT_1 PF00078.27 KFQ91705.1 - 0.0096 15.5 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) OMPdecase PF00215.24 KFQ91706.1 - 6.1e-76 254.9 0.0 1e-75 254.2 0.0 1.4 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 KFQ91706.1 - 2.5e-12 46.6 0.0 5e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pkinase PF00069.25 KFQ91707.1 - 1.4e-18 67.2 0.0 1.6e-18 67.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ91707.1 - 1.8e-06 27.5 0.0 2.3e-06 27.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase T2SSK PF03934.13 KFQ91707.1 - 0.098 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K CCDC14 PF15254.6 KFQ91708.1 - 0 1115.6 42.3 0 1115.5 42.3 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 14 GldM_N PF12081.8 KFQ91708.1 - 3.6 7.6 14.1 0.6 10.2 8.8 2.2 2 0 0 2 2 2 0 GldM N-terminal domain I-set PF07679.16 KFQ91709.1 - 2.7e-211 684.4 10.6 3.7e-28 97.4 0.1 10.1 10 0 0 10 10 10 9 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ91709.1 - 4e-131 427.9 10.6 3e-15 56.6 0.0 10.4 10 0 0 10 10 10 9 Immunoglobulin domain ig PF00047.25 KFQ91709.1 - 6e-90 295.6 10.1 1.3e-10 41.3 0.0 9.6 9 0 0 9 9 9 9 Immunoglobulin domain Ig_2 PF13895.6 KFQ91709.1 - 1.3e-82 272.2 12.9 8.3e-11 42.1 0.0 10.2 10 0 0 10 10 10 9 Immunoglobulin domain Pkinase PF00069.25 KFQ91709.1 - 1.9e-76 256.9 1.3 2.4e-76 256.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain 23ISL PF16620.5 KFQ91709.1 - 7.3e-51 172.6 19.4 7.3e-51 172.6 19.4 3.3 3 1 0 3 3 1 1 Unstructured linker between I-set domains 2 and 3 on MYLCK V-set PF07686.17 KFQ91709.1 - 3.8e-40 136.4 25.8 4.6e-05 23.5 0.2 16.5 10 8 1 12 12 12 8 Immunoglobulin V-set domain Pkinase_Tyr PF07714.17 KFQ91709.1 - 2.3e-35 122.1 0.0 4.1e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C2-set_2 PF08205.12 KFQ91709.1 - 1.4e-25 89.2 3.3 0.014 15.5 0.0 9.1 8 0 0 8 8 8 6 CD80-like C2-set immunoglobulin domain fn3 PF00041.21 KFQ91709.1 - 1.3e-16 60.7 0.3 5.4e-16 58.7 0.3 2.2 1 0 0 1 1 1 1 Fibronectin type III domain Ig_6 PF18452.1 KFQ91709.1 - 3.1e-10 39.4 0.2 0.3 10.7 0.0 6.6 7 0 0 7 7 7 2 Immunoglobulin domain Receptor_2B4 PF11465.8 KFQ91709.1 - 3.5e-10 40.1 2.2 1.2 9.4 0.0 8.0 9 0 0 9 9 9 2 Natural killer cell receptor 2B4 BiPBP_C PF06832.12 KFQ91709.1 - 4.8e-10 39.3 0.0 8.9 6.4 0.0 7.9 8 0 0 8 8 7 0 Penicillin-Binding Protein C-terminus Family Ig_C17orf99 PF17736.1 KFQ91709.1 - 2.9e-09 36.8 0.5 1.5 8.9 0.0 7.4 10 0 0 10 10 7 2 C17orf99 Ig domain Ig_4 PF16680.5 KFQ91709.1 - 4.2e-08 33.3 13.9 1.4 9.3 0.0 9.0 9 0 0 9 9 9 2 T-cell surface glycoprotein CD3 delta chain Herpes_gE PF02480.16 KFQ91709.1 - 3.8e-07 29.2 0.4 0.015 14.0 0.0 5.1 5 1 1 6 6 6 1 Alphaherpesvirus glycoprotein E Izumo-Ig PF16706.5 KFQ91709.1 - 1.7e-06 28.0 12.3 0.72 10.0 0.0 8.5 9 0 0 9 9 9 2 Izumo-like Immunoglobulin domain Kinase-like PF14531.6 KFQ91709.1 - 0.00042 19.7 0.0 0.0015 18.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFQ91709.1 - 0.024 14.0 0.1 0.055 12.8 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFQ91709.1 - 0.038 13.6 0.1 0.093 12.3 0.1 1.6 1 0 0 1 1 1 0 RIO1 family V-set_CD47 PF08204.11 KFQ91709.1 - 0.039 13.9 5.8 18 5.4 0.0 5.7 7 0 0 7 7 7 0 CD47 immunoglobulin-like domain PTPLA PF04387.14 KFQ91711.1 - 2e-42 144.7 10.3 2.2e-42 144.6 10.3 1.0 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Guanylate_cyc PF00211.20 KFQ91713.1 - 3.4e-122 404.9 3.0 1.2e-62 210.8 0.5 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 KFQ91713.1 - 6.2e-56 190.3 3.8 6.2e-56 190.3 3.8 2.3 2 0 0 2 2 2 1 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF1053 PF06327.14 KFQ91713.1 - 1.7e-25 89.5 0.4 4.9e-25 88.1 0.4 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) HNOBA PF07701.14 KFQ91713.1 - 0.0014 18.1 1.2 0.4 10.1 0.1 2.5 2 0 0 2 2 2 2 Heme NO binding associated TBK1_ULD PF18396.1 KFQ91713.1 - 0.021 14.8 0.1 0.048 13.6 0.1 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Longin PF13774.6 KFQ91714.1 - 5.4e-20 71.2 0.2 1.1e-19 70.3 0.2 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Thioredoxin PF00085.20 KFQ91716.1 - 3.5e-72 238.9 2.9 2e-24 85.6 0.0 4.1 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_2 PF13098.6 KFQ91716.1 - 7.3e-27 94.0 4.4 1.1e-07 32.3 0.0 4.2 4 1 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFQ91716.1 - 1.3e-17 63.8 0.1 2.3e-05 24.5 0.0 3.6 3 0 0 3 3 3 3 Thioredoxin-like AhpC-TSA PF00578.21 KFQ91716.1 - 6.1e-17 61.7 0.6 2.1e-05 24.4 0.0 3.6 3 0 0 3 3 3 3 AhpC/TSA family Thioredoxin_8 PF13905.6 KFQ91716.1 - 1.1e-14 54.5 0.6 0.0023 18.2 0.0 5.3 3 2 2 5 5 5 3 Thioredoxin-like OST3_OST6 PF04756.13 KFQ91716.1 - 5.4e-14 52.2 0.0 2.4e-05 23.8 0.0 3.1 2 1 1 3 3 3 3 OST3 / OST6 family, transporter family Redoxin PF08534.10 KFQ91716.1 - 1.6e-12 47.4 1.5 0.0057 16.4 0.0 3.4 2 1 1 3 3 3 3 Redoxin Thioredoxin_6 PF13848.6 KFQ91716.1 - 3.6e-10 40.0 1.1 0.022 14.7 0.0 4.3 5 0 0 5 5 5 3 Thioredoxin-like domain TraF PF13728.6 KFQ91716.1 - 3.2e-08 33.7 0.1 0.1 12.4 0.0 3.7 3 1 0 3 3 3 2 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 KFQ91716.1 - 5.9e-08 32.6 0.1 0.085 12.6 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin HyaE PF07449.11 KFQ91716.1 - 5.7e-05 23.0 0.0 1.1 9.3 0.0 3.8 4 1 0 4 4 4 2 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 KFQ91716.1 - 0.00042 20.3 0.2 0.41 10.7 0.0 3.4 3 0 0 3 3 3 1 Thioredoxin domain Thioredoxin_4 PF13462.6 KFQ91716.1 - 0.032 14.4 6.6 5.8 7.0 0.3 3.6 2 1 1 3 3 3 0 Thioredoxin Glutaredoxin PF00462.24 KFQ91716.1 - 0.072 13.3 13.3 1.4 9.2 0.2 4.5 4 1 0 4 4 4 0 Glutaredoxin DSBA PF01323.20 KFQ91716.1 - 0.66 9.7 4.6 21 4.8 0.2 4.3 3 3 2 5 5 5 0 DSBA-like thioredoxin domain Sema PF01403.19 KFQ91717.1 - 2.1e-132 442.0 0.7 4.2e-132 441.0 0.0 1.9 2 0 0 2 2 2 1 Sema domain TSP_1 PF00090.19 KFQ91717.1 - 9.2e-43 144.2 96.1 1.4e-10 41.2 9.0 7.7 7 0 0 7 7 7 5 Thrombospondin type 1 domain 7TM_GPCR_Srz PF10325.9 KFQ91717.1 - 0.076 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz MFS_1 PF07690.16 KFQ91718.1 - 7.2e-06 25.2 28.4 7.2e-06 25.2 28.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily AceK PF06315.11 KFQ91718.1 - 0.2 10.1 0.0 0.27 9.7 0.0 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) Cupin_8 PF13621.6 KFQ91719.1 - 8e-35 120.8 0.0 1.2e-34 120.2 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KFQ91719.1 - 1.2e-08 34.8 0.0 1.9e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 KFQ91719.1 - 0.0027 18.1 0.0 0.0058 17.1 0.0 1.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase Pox_C7_F8A PF03287.14 KFQ91719.1 - 0.12 12.3 0.0 4.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Poxvirus C7/F8A protein PTR2 PF00854.21 KFQ91720.1 - 4.8e-48 163.9 5.0 7e-48 163.4 5.0 1.2 1 0 0 1 1 1 1 POT family EAF PF09816.9 KFQ91721.1 - 1.6e-14 54.1 0.1 6.2e-14 52.2 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor AF-4 PF05110.13 KFQ91721.1 - 0.0031 15.7 25.6 0.0042 15.3 25.6 1.3 1 0 0 1 1 1 1 AF-4 proto-oncoprotein PAN_3 PF08277.12 KFQ91721.1 - 0.033 14.0 0.1 0.081 12.7 0.1 1.7 1 0 0 1 1 1 0 PAN-like domain Macoilin PF09726.9 KFQ91721.1 - 0.27 9.7 11.4 0.29 9.6 11.4 1.1 1 0 0 1 1 1 0 Macoilin family Lin-8 PF03353.15 KFQ91721.1 - 0.32 10.5 9.1 0.39 10.2 9.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Cwf_Cwc_15 PF04889.12 KFQ91721.1 - 0.85 9.3 11.9 1.5 8.5 11.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.9 KFQ91721.1 - 3.1 7.4 25.5 5.3 6.6 25.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IQ PF00612.27 KFQ91722.1 - 2e-12 45.7 24.1 1.1e-06 27.9 0.8 5.5 5 0 0 5 5 5 4 IQ calmodulin-binding motif RNase_HII PF01351.18 KFQ91722.1 - 0.097 12.5 0.2 0.24 11.2 0.2 1.6 1 0 0 1 1 1 0 Ribonuclease HII RhoGEF PF00621.20 KFQ91724.1 - 7e-38 130.7 3.0 1.4e-37 129.7 3.0 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 KFQ91724.1 - 0.031 14.1 0.0 0.077 12.8 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Sda PF08970.10 KFQ91724.1 - 0.095 12.4 1.0 0.23 11.2 1.0 1.7 1 0 0 1 1 1 0 Sporulation inhibitor A MKRN1_C PF15815.5 KFQ91724.1 - 0.37 11.2 2.4 3.6 8.0 0.3 2.8 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase makorin-1, C-terminal hNIFK_binding PF12196.8 KFQ91725.1 - 6.5e-20 70.3 0.9 1.1e-19 69.6 0.9 1.4 1 0 0 1 1 1 1 FHA Ki67 binding domain of hNIFK RRM_1 PF00076.22 KFQ91725.1 - 2.2e-05 24.2 0.0 4.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Olfactory_mark PF06554.12 KFQ91725.1 - 0.047 13.4 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Olfactory marker protein CLASP_N PF12348.8 KFQ91726.1 - 8.1e-56 189.1 14.6 3.6e-37 128.1 0.5 4.9 4 1 0 4 4 4 3 CLASP N terminal HEAT PF02985.22 KFQ91726.1 - 2.8e-19 67.6 9.1 1.2e-05 25.1 0.0 9.7 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.6 KFQ91726.1 - 5.3e-12 46.0 2.0 0.016 15.7 0.1 6.1 6 0 0 6 6 5 3 HEAT-like repeat HEAT_2 PF13646.6 KFQ91726.1 - 1.4e-10 41.4 4.0 0.1 13.0 0.0 7.8 5 2 4 10 10 10 4 HEAT repeats Sec7_N PF12783.7 KFQ91726.1 - 9.8e-08 32.1 7.5 0.017 15.0 0.0 5.3 5 0 0 5 5 5 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Vac14_Fab1_bd PF12755.7 KFQ91726.1 - 2.1e-07 31.4 1.6 1.9 9.2 0.0 6.0 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KFQ91726.1 - 2.3e-07 31.0 11.3 0.0046 17.0 0.9 6.4 6 1 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 KFQ91726.1 - 4e-06 27.0 9.6 0.061 13.5 0.1 5.8 6 2 1 7 7 6 2 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KFQ91726.1 - 4.7e-05 22.1 9.7 1.2 7.6 0.0 5.7 5 2 0 7 7 7 3 Adaptin N terminal region Tti2 PF10521.9 KFQ91726.1 - 0.00013 21.7 4.8 2.4 7.6 0.0 5.4 4 1 0 5 5 5 2 Tti2 family ParcG PF10274.9 KFQ91726.1 - 0.00035 20.7 1.6 0.0075 16.4 0.1 3.4 2 1 1 3 3 3 1 Parkin co-regulated protein TFCD_C PF12612.8 KFQ91726.1 - 0.0012 18.8 1.6 0.026 14.4 0.2 3.6 3 1 0 3 3 3 1 Tubulin folding cofactor D C terminal MMS19_C PF12460.8 KFQ91726.1 - 0.002 17.3 1.4 1.6 7.8 0.1 3.4 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal Dopey_N PF04118.14 KFQ91726.1 - 0.003 16.7 2.9 0.36 9.9 0.1 3.6 4 0 0 4 4 4 1 Dopey, N-terminal MMS19_N PF14500.6 KFQ91726.1 - 0.0034 17.0 6.0 0.61 9.6 0.2 4.6 3 2 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II TAN PF11640.8 KFQ91726.1 - 0.0075 16.4 1.3 0.22 11.7 0.1 3.9 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair XRN_M PF17846.1 KFQ91726.1 - 0.016 14.2 0.0 0.032 13.2 0.0 1.4 1 0 0 1 1 1 0 Xrn1 helical domain CTK3 PF12243.8 KFQ91726.1 - 0.065 13.2 0.1 5.2 7.1 0.0 2.8 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 HMW1C_N PF18071.1 KFQ91726.1 - 0.068 13.0 0.0 2.2 8.1 0.0 2.5 2 0 0 2 2 2 0 HMW1C N-terminal RasGEF_N_2 PF14663.6 KFQ91726.1 - 0.085 13.3 0.2 8.2 6.9 0.1 3.8 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain TPR_20 PF14561.6 KFQ91726.1 - 0.097 13.0 3.1 0.35 11.2 0.4 3.4 2 1 1 3 3 2 0 Tetratricopeptide repeat CP2 PF04516.15 KFQ91727.1 - 7.3e-57 192.3 0.0 1.1e-56 191.8 0.0 1.1 1 0 0 1 1 1 1 CP2 transcription factor SAM_3 PF18016.1 KFQ91727.1 - 2.3e-17 62.5 0.0 4.2e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFQ91727.1 - 0.021 14.8 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain zf-C2H2 PF00096.26 KFQ91728.1 - 1.4e-18 66.2 36.9 0.00034 20.9 0.5 6.7 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ91728.1 - 4.4e-12 45.8 30.6 1.7e-06 28.2 1.4 5.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ91728.1 - 1e-05 25.9 32.0 0.0052 17.5 0.3 6.2 6 0 0 6 6 6 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFQ91728.1 - 1.7e-05 25.4 26.6 0.026 15.1 0.1 5.8 2 1 2 5 5 5 2 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 KFQ91728.1 - 0.18 11.9 16.8 1.6 8.8 3.4 3.5 2 1 1 3 3 3 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 KFQ91728.1 - 5.6 7.1 5.4 2.8 8.0 2.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger PcF PF09461.10 KFQ91728.1 - 9 6.8 7.8 44 4.6 0.3 4.1 3 1 1 4 4 4 0 Phytotoxin PcF protein Ras PF00071.22 KFQ91729.1 - 7.8e-52 175.1 0.2 8.8e-52 175.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ91729.1 - 3e-21 75.9 0.0 4.2e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ91729.1 - 4.3e-10 39.3 0.0 5.1e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFQ91729.1 - 5.6e-09 36.1 0.1 5.9e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KFQ91729.1 - 1.6e-05 24.4 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KFQ91729.1 - 0.0001 21.9 0.0 0.00037 20.1 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFQ91729.1 - 0.00043 20.3 0.0 0.0006 19.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFQ91729.1 - 0.00066 19.1 0.0 0.00087 18.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_25 PF13481.6 KFQ91729.1 - 0.0029 17.2 0.0 0.0038 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 KFQ91729.1 - 0.0063 15.8 0.0 0.81 8.9 0.0 2.1 2 0 0 2 2 2 2 Septin FeoB_N PF02421.18 KFQ91729.1 - 0.039 13.5 0.0 0.54 9.8 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B FERM_C PF09380.10 KFQ91730.1 - 1e-21 77.1 0.0 1.8e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FA PF08736.11 KFQ91730.1 - 2.5e-14 53.1 12.0 5.9e-14 51.9 12.0 1.7 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_N PF09379.10 KFQ91730.1 - 5.8e-14 51.8 0.2 2.4e-13 49.8 0.1 2.1 2 0 0 2 2 2 1 FERM N-terminal domain FERM_M PF00373.18 KFQ91730.1 - 5.6e-13 49.3 2.1 2.9e-12 47.0 0.6 2.5 2 1 0 2 2 2 1 FERM central domain Y_phosphatase PF00102.27 KFQ91731.1 - 2.2e-79 266.3 0.5 3.5e-79 265.7 0.5 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FERM_C PF09380.10 KFQ91731.1 - 7.3e-27 93.6 0.4 1.7e-26 92.4 0.4 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 KFQ91731.1 - 1.4e-24 86.7 1.2 2.5e-24 86.0 0.4 1.9 2 0 0 2 2 2 1 FERM central domain PDZ PF00595.24 KFQ91731.1 - 6.8e-20 71.2 0.0 1.7e-19 70.0 0.0 1.7 1 0 0 1 1 1 1 PDZ domain FERM_N PF09379.10 KFQ91731.1 - 6.2e-19 67.7 0.0 3.9e-18 65.2 0.0 2.2 2 0 0 2 2 2 1 FERM N-terminal domain FA PF08736.11 KFQ91731.1 - 3.1e-14 52.8 0.9 3.1e-14 52.8 0.9 2.1 2 0 0 2 2 2 1 FERM adjacent (FA) PDZ_6 PF17820.1 KFQ91731.1 - 0.00026 20.8 0.0 0.00054 19.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain DSPc PF00782.20 KFQ91731.1 - 0.00037 20.3 0.0 0.00082 19.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFQ91731.1 - 0.00053 20.1 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KFQ91731.1 - 0.00082 19.4 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Ras PF00071.22 KFQ91733.1 - 2.7e-53 179.9 0.0 3.2e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ91733.1 - 3e-20 72.6 0.0 4.8e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KFQ91733.1 - 4.1e-07 29.7 0.1 1e-06 28.5 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KFQ91733.1 - 2.2e-06 27.2 0.0 2.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFQ91733.1 - 3.2e-05 23.9 0.6 0.028 14.3 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFQ91733.1 - 0.0024 18.0 0.0 0.0043 17.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KFQ91733.1 - 0.0048 16.7 0.1 0.029 14.1 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KFQ91733.1 - 0.072 13.5 0.1 0.12 12.7 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1_Xtn PF16897.5 KFQ91733.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Gtr1_RagA PF04670.12 KFQ91733.1 - 0.12 11.7 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region F5_F8_type_C PF00754.25 KFQ91735.1 - 3.8e-16 59.4 1.8 4.1e-16 59.3 1.8 1.0 1 0 0 1 1 1 1 F5/8 type C domain Laminin_G_2 PF02210.24 KFQ91736.1 - 3.5e-62 208.6 0.7 4.8e-22 78.9 0.0 3.2 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.23 KFQ91736.1 - 2.3e-47 160.5 0.1 1.3e-18 67.4 0.0 3.3 3 0 0 3 3 3 3 Laminin G domain Laminin_G_3 PF13385.6 KFQ91736.1 - 1.5e-11 44.6 0.1 2.1e-05 24.7 0.0 3.5 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 KFQ91736.1 - 1.2e-07 31.9 33.7 7.7e-05 22.9 9.1 3.6 3 0 0 3 3 3 2 EGF-like domain EGF_2 PF07974.13 KFQ91736.1 - 0.012 15.9 12.8 0.012 15.9 12.8 3.8 4 0 0 4 4 4 0 EGF-like domain hEGF PF12661.7 KFQ91736.1 - 1.2 9.8 31.6 0.033 14.8 8.1 4.2 4 0 0 4 4 4 0 Human growth factor-like EGF Syndecan PF01034.20 KFQ91737.1 - 0.00061 19.7 0.2 0.00089 19.1 0.2 1.3 1 0 0 1 1 1 1 Syndecan domain Protocadherin PF08374.11 KFQ91737.1 - 0.0033 17.4 0.0 0.0033 17.4 0.0 1.1 1 0 0 1 1 1 1 Protocadherin Spore_SspJ PF09575.10 KFQ91737.1 - 0.016 15.5 0.8 0.023 15.0 0.8 1.2 1 0 0 1 1 1 0 Small spore protein J (Spore_SspJ) EphA2_TM PF14575.6 KFQ91737.1 - 0.028 15.3 0.0 0.033 15.1 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MAP17 PF15807.5 KFQ91737.1 - 0.028 14.6 0.0 0.035 14.4 0.0 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 FTCD_C PF04961.12 KFQ91737.1 - 0.047 13.5 0.1 0.051 13.3 0.1 1.1 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Chordopox_A13L PF05961.11 KFQ91737.1 - 0.066 13.4 0.0 0.081 13.2 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Baculo_11_kDa PF06143.11 KFQ91737.1 - 0.089 12.4 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF202 PF02656.15 KFQ91737.1 - 0.11 12.9 0.2 0.14 12.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF202) FAM163 PF15069.6 KFQ91737.1 - 0.13 12.7 0.0 0.14 12.6 0.0 1.1 1 0 0 1 1 1 0 FAM163 family DUF4692 PF15763.5 KFQ91737.1 - 0.14 12.6 0.0 0.17 12.4 0.0 1.1 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) ODV-E18 PF10717.9 KFQ91737.1 - 0.16 11.9 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF4381 PF14316.6 KFQ91737.1 - 0.21 11.8 0.0 0.22 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Adeno_E3_CR2 PF02439.15 KFQ91737.1 - 0.56 10.0 6.4 0.9 9.3 6.4 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 BAR PF03114.18 KFQ91738.1 - 3.4e-43 148.0 9.4 4.4e-43 147.6 9.4 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 KFQ91738.1 - 5.5e-12 45.4 0.2 2.6e-11 43.2 0.2 2.0 1 1 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFQ91738.1 - 3.7e-07 29.7 0.2 1e-06 28.2 0.2 1.8 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFQ91738.1 - 4.6e-06 26.2 0.0 1.1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 KFQ91738.1 - 0.0016 18.2 8.7 0.0041 16.9 8.4 1.8 1 1 1 2 2 2 1 BAR domain of APPL family Jnk-SapK_ap_N PF09744.9 KFQ91738.1 - 0.017 15.4 1.5 0.017 15.4 1.5 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 OmpH PF03938.14 KFQ91738.1 - 0.035 14.4 0.7 0.035 14.4 0.7 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) CEP209_CC5 PF16574.5 KFQ91738.1 - 0.055 13.6 0.8 0.055 13.6 0.8 2.1 2 0 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 DUF3104 PF11302.8 KFQ91738.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) BLOC1_2 PF10046.9 KFQ91738.1 - 0.65 10.3 9.6 0.37 11.1 1.8 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Arfaptin PF06456.13 KFQ91738.1 - 1.1 8.8 7.7 2.7 7.5 7.7 1.7 1 1 0 1 1 1 0 Arfaptin-like domain PTS_IIA PF02255.16 KFQ91738.1 - 1.8 8.6 6.8 6.9 6.8 1.9 2.8 2 1 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit p450 PF00067.22 KFQ91739.1 - 6.2e-102 341.7 0.0 6.9e-102 341.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Importin_rep_6 PF18829.1 KFQ91739.1 - 0.046 13.8 0.0 0.099 12.8 0.0 1.6 1 0 0 1 1 1 0 Importin repeat 6 ERCC3_RAD25_C PF16203.5 KFQ91740.1 - 2.2e-124 413.6 2.0 3.7e-124 412.8 2.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KFQ91740.1 - 1.4e-39 135.2 0.0 4e-39 133.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFQ91740.1 - 5.5e-16 59.0 0.0 1.6e-15 57.5 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFQ91740.1 - 1.9e-09 37.8 0.1 4.9e-09 36.5 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KFQ91740.1 - 0.0013 17.5 0.0 0.0021 16.8 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF2605 PF10792.9 KFQ91740.1 - 0.055 13.4 0.3 0.18 11.7 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) Pkinase PF00069.25 KFQ91741.1 - 4.9e-66 222.8 0.0 6.3e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ91741.1 - 3.4e-39 134.7 0.0 4.5e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.24 KFQ91741.1 - 6e-13 48.5 0.1 1.2e-12 47.6 0.1 1.5 1 0 0 1 1 1 1 PB1 domain Kinase-like PF14531.6 KFQ91741.1 - 5.5e-06 25.9 0.0 0.0014 18.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like FTA2 PF13095.6 KFQ91741.1 - 0.032 13.8 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KFQ91741.1 - 0.071 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KFQ91741.1 - 0.19 10.8 0.0 1.2 8.1 0.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP7 adh_short_C2 PF13561.6 KFQ91742.1 - 6.6e-48 163.3 0.2 7.5e-48 163.1 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFQ91742.1 - 1.5e-38 132.2 0.3 1.9e-38 131.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase CABS1 PF15367.6 KFQ91742.1 - 0.14 11.3 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 Ku_N PF03731.15 KFQ91744.1 - 1.9e-58 197.8 3.5 4e-58 196.8 0.2 2.4 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.16 KFQ91744.1 - 1e-45 155.9 1.3 1.7e-45 155.2 1.3 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 KFQ91744.1 - 6.7e-29 100.5 1.8 6.7e-29 100.5 1.8 3.0 4 0 0 4 4 4 1 Ku C terminal domain like Ku_C PF03730.14 KFQ91744.1 - 6.1e-21 74.9 2.4 2e-20 73.2 2.4 2.0 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm VWA PF00092.28 KFQ91744.1 - 0.0079 16.5 0.4 0.034 14.4 0.1 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain PDDEXK_7 PF04411.12 KFQ91744.1 - 0.072 13.1 0.5 0.17 11.8 0.5 1.5 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Cnl2_NKP2 PF09447.10 KFQ91744.1 - 4.5 7.5 5.5 2.6 8.2 0.1 3.2 4 0 0 4 4 4 0 Cnl2/NKP2 family protein Vint PF14623.6 KFQ91745.1 - 0.16 11.8 0.1 0.16 11.7 0.1 1.1 1 0 0 1 1 1 0 Hint-domain RINGv PF12906.7 KFQ91746.1 - 4.5e-10 39.5 15.0 8.9e-10 38.5 15.0 1.5 1 0 0 1 1 1 1 RING-variant domain HARP PF07443.13 KFQ91747.1 - 1.4e-52 175.1 0.9 4.1e-25 87.2 0.1 2.5 2 0 0 2 2 2 2 HepA-related protein (HARP) SNF2_N PF00176.23 KFQ91747.1 - 4.1e-25 88.2 0.0 6.4e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFQ91747.1 - 6.8e-15 55.4 0.1 3e-14 53.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFQ91747.1 - 9.6e-07 29.0 0.0 0.00012 22.1 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFQ91747.1 - 5.4e-06 25.8 0.2 0.00015 21.1 0.1 2.2 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Flavi_DEAD PF07652.14 KFQ91747.1 - 0.024 14.6 0.0 0.8 9.7 0.0 2.6 2 0 0 2 2 2 0 Flavivirus DEAD domain Ribosomal_L37ae PF01780.19 KFQ91748.1 - 3.9e-47 158.2 11.2 4.4e-47 158.1 11.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 KFQ91748.1 - 0.0047 17.0 4.8 0.0073 16.4 4.2 1.6 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Elf1 PF05129.13 KFQ91748.1 - 0.011 15.8 0.3 0.016 15.3 0.3 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Rsm1 PF08600.10 KFQ91748.1 - 0.013 15.6 0.6 0.019 15.1 0.6 1.3 1 0 0 1 1 1 0 Rsm1-like Zn_Tnp_IS1595 PF12760.7 KFQ91748.1 - 0.052 13.5 1.8 0.076 13.0 1.8 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C4_ClpX PF06689.13 KFQ91748.1 - 0.14 12.1 4.1 0.43 10.5 4.1 1.9 1 1 0 1 1 1 0 ClpX C4-type zinc finger zf-BED PF02892.15 KFQ91748.1 - 0.77 9.8 6.0 5.3 7.2 0.7 2.2 1 1 1 2 2 2 0 BED zinc finger Thyroglobulin_1 PF00086.18 KFQ91749.1 - 2.5e-18 65.5 0.8 4.7e-18 64.6 0.8 1.5 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat Myosin_head PF00063.21 KFQ91750.1 - 5.6e-92 309.1 0.0 3e-91 306.7 0.0 2.2 2 1 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KFQ91750.1 - 0.00017 19.6 106.8 0.00017 19.6 106.8 3.3 1 1 1 2 2 2 1 Myosin tail ADIP PF11559.8 KFQ91750.1 - 0.00065 19.8 13.4 0.00065 19.8 13.4 8.6 2 2 7 9 9 9 3 Afadin- and alpha -actinin-Binding Taxilin PF09728.9 KFQ91750.1 - 0.00072 18.8 31.4 0.00072 18.8 31.4 5.7 1 1 2 5 5 5 2 Myosin-like coiled-coil protein DivIC PF04977.15 KFQ91750.1 - 0.024 14.4 0.0 0.024 14.4 0.0 9.5 6 2 2 8 8 8 0 Septum formation initiator IQ PF00612.27 KFQ91750.1 - 0.027 14.2 0.3 0.027 14.2 0.3 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif LPP PF04728.13 KFQ91750.1 - 0.81 10.1 13.3 8.2 6.9 2.1 3.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Pkinase PF00069.25 KFQ91751.1 - 7e-74 248.5 0.0 1.1e-72 244.6 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ91751.1 - 6.8e-29 100.9 0.0 1.1e-28 100.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 KFQ91751.1 - 7.6e-19 68.1 4.6 1.4e-18 67.2 4.6 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain PH PF00169.29 KFQ91751.1 - 8.2e-11 42.4 0.3 1.6e-10 41.4 0.3 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 KFQ91751.1 - 0.0017 17.7 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFQ91751.1 - 0.0075 15.1 0.0 0.016 14.0 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Crystall PF00030.19 KFQ91752.1 - 7.6e-61 202.3 1.7 2.2e-30 104.7 0.2 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin IL4_i_Ig PF18258.1 KFQ91752.1 - 6.7e-05 23.0 0.8 4.3 7.6 0.0 3.9 2 2 2 4 4 4 2 Interleukin-4 inducing immunoglobulin-binding domain Inhibitor_I36 PF03995.13 KFQ91752.1 - 9.5e-05 22.2 0.0 0.19 11.7 0.0 2.3 2 0 0 2 2 2 2 Peptidase inhibitor family I36 Crystall_3 PF08964.10 KFQ91752.1 - 0.056 13.6 2.4 1.5 9.0 0.2 3.1 2 2 1 3 3 3 0 Beta/Gamma crystallin Syncollin PF15138.6 KFQ91752.1 - 0.13 12.4 0.1 2.2 8.5 0.0 2.3 1 1 1 2 2 2 0 Syncollin Crystall PF00030.19 KFQ91753.1 - 3e-56 187.6 0.5 3e-28 97.8 0.1 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.13 KFQ91753.1 - 0.00011 22.1 0.0 0.0064 16.4 0.0 2.5 2 1 0 2 2 2 1 Peptidase inhibitor family I36 IL4_i_Ig PF18258.1 KFQ91753.1 - 0.00022 21.4 1.3 8.3 6.7 0.0 4.2 1 1 3 4 4 4 3 Interleukin-4 inducing immunoglobulin-binding domain SNF PF00209.18 KFQ91754.1 - 1.5e-142 475.9 20.1 1.7e-142 475.8 20.1 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family PGF-CTERM PF18204.1 KFQ91754.1 - 0.43 10.6 3.2 0.54 10.3 0.8 2.4 2 0 0 2 2 2 0 PGF-CTERM motif GPCR_chapero_1 PF11904.8 KFQ91755.1 - 9.1e-97 324.2 0.1 9.1e-97 324.2 0.1 1.5 2 0 0 2 2 2 1 GPCR-chaperone Ank_4 PF13637.6 KFQ91755.1 - 1.8e-11 44.3 0.0 4.5e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFQ91755.1 - 5.2e-11 43.0 0.0 1.2e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFQ91755.1 - 6.7e-10 38.4 0.0 0.0022 18.3 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KFQ91755.1 - 3.6e-09 36.7 0.0 2.1e-06 27.9 0.0 3.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KFQ91755.1 - 2e-07 31.1 0.0 0.011 16.1 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat YscJ_FliF PF01514.17 KFQ91755.1 - 0.11 12.1 0.6 0.23 11.1 0.2 1.7 2 0 0 2 2 2 0 Secretory protein of YscJ/FliF family UIM PF02809.20 KFQ91755.1 - 0.15 12.0 20.1 0.28 11.2 1.6 4.3 4 0 0 4 4 4 0 Ubiquitin interaction motif GIT1_C PF12205.8 KFQ91756.1 - 2.8e-46 156.4 4.6 2.8e-46 156.4 4.6 2.7 2 0 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term GIT_CC PF16559.5 KFQ91756.1 - 5.7e-28 96.6 6.5 2.1e-27 94.8 6.5 2.0 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor GIT_SHD PF08518.11 KFQ91756.1 - 2.6e-27 94.1 1.6 7.9e-14 51.0 0.1 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT ArfGap PF01412.18 KFQ91756.1 - 1.3e-24 86.5 1.7 2.8e-24 85.4 0.0 2.5 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf Ank_2 PF12796.7 KFQ91756.1 - 5.6e-09 36.5 0.0 1.9e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ91756.1 - 3.5e-08 33.8 0.0 4.7e-05 23.9 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFQ91756.1 - 3.7e-07 30.3 0.0 1.6e-06 28.3 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KFQ91756.1 - 0.001 19.4 0.3 0.0091 16.4 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 KFQ91756.1 - 0.01 16.3 0.0 0.35 11.6 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat Sen15 PF09631.10 KFQ91756.1 - 0.012 15.9 0.2 0.059 13.7 0.0 2.3 2 0 0 2 2 2 0 Sen15 protein TTRAP PF14203.6 KFQ91756.1 - 0.032 14.2 0.6 0.24 11.4 0.1 2.7 3 0 0 3 3 3 0 Putative tranposon-transfer assisting protein Shugoshin_N PF07558.11 KFQ91756.1 - 0.084 12.7 7.0 0.28 11.1 7.0 1.9 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DMPK_coil PF08826.10 KFQ91756.1 - 0.11 12.6 2.1 0.35 11.0 1.1 2.5 2 0 0 2 2 2 0 DMPK coiled coil domain like T7SS_ESX_EspC PF10824.8 KFQ91756.1 - 0.91 10.0 5.0 1.7 9.1 0.1 3.5 4 0 0 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm CRIC_ras_sig PF10534.9 KFQ91756.1 - 9.3 6.5 10.6 0.45 10.7 0.3 4.0 5 1 1 6 6 5 0 Connector enhancer of kinase suppressor of ras TPH PF13868.6 KFQ91757.1 - 9.2e-27 93.5 132.5 1e-26 93.3 132.5 1.0 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain GLTP PF08718.11 KFQ91758.1 - 2.9e-29 102.3 0.0 4.5e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) GN3L_Grn1 PF08701.11 KFQ91758.1 - 0.047 13.8 1.3 0.063 13.4 0.3 1.7 2 0 0 2 2 2 0 GNL3L/Grn1 putative GTPase FliS PF02561.14 KFQ91758.1 - 0.063 13.5 0.4 2.2 8.6 0.1 2.6 2 1 0 3 3 3 0 Flagellar protein FliS Ion_trans PF00520.31 KFQ91759.1 - 2.8e-15 56.2 17.5 3.9e-15 55.8 17.5 1.1 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 KFQ91759.1 - 1.8e-14 54.1 0.3 6.2e-06 26.7 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFQ91759.1 - 4e-10 39.7 0.1 0.00062 20.1 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KFQ91759.1 - 5.3e-10 38.7 0.1 0.0017 18.6 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KFQ91759.1 - 4.9e-08 33.4 0.4 0.012 16.2 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFQ91759.1 - 5.7e-07 29.7 0.2 0.34 11.3 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) GHMP_kinases_N PF00288.26 KFQ91760.1 - 1.5e-20 73.2 0.5 4.2e-20 71.7 0.5 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KFQ91760.1 - 2.2e-06 27.9 2.5 2.3e-06 27.9 0.0 2.3 3 0 0 3 3 3 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 KFQ91760.1 - 0.0047 16.5 0.0 0.0099 15.4 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Cob_adeno_trans PF01923.18 KFQ91761.1 - 5.1e-56 189.3 0.0 5.8e-56 189.1 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase T2SSF PF00482.23 KFQ91761.1 - 0.16 11.9 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F HECT PF00632.25 KFQ91762.1 - 6.3e-94 314.9 0.0 1.4e-93 313.8 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KFQ91762.1 - 0.00092 18.8 3.2 0.0038 16.9 3.2 2.2 1 0 0 1 1 1 1 IQ calmodulin-binding motif BTB_2 PF02214.22 KFQ91763.1 - 9.9e-21 73.9 0.0 1.7e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KFQ91763.1 - 0.00012 22.3 0.0 0.00024 21.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KFQ91763.1 - 0.011 15.9 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Myosin_TH1 PF06017.13 KFQ91764.1 - 7e-33 113.9 1.5 9.1e-33 113.5 1.5 1.1 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding Carm_PH PF17888.1 KFQ91764.1 - 0.089 13.2 0.2 0.19 12.1 0.2 1.8 1 1 0 1 1 1 0 Carmil pleckstrin homology domain ACC_central PF08326.12 KFQ91765.1 - 2.8e-282 938.4 0.3 3.5e-282 938.0 0.3 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KFQ91765.1 - 1.4e-179 597.9 0.0 1.9e-179 597.5 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KFQ91765.1 - 6.1e-52 176.2 0.1 1.2e-51 175.2 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KFQ91765.1 - 5.5e-23 81.1 0.0 1.7e-22 79.5 0.0 2.0 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KFQ91765.1 - 4.1e-19 69.1 0.0 1e-18 67.9 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KFQ91765.1 - 1.1e-12 47.6 0.0 3.1e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KFQ91765.1 - 6.8e-05 22.5 0.0 0.00015 21.4 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFQ91765.1 - 9.7e-05 22.0 0.1 0.00021 20.9 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KFQ91765.1 - 0.0052 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain UDG PF03167.19 KFQ91766.1 - 2.2e-24 86.2 0.0 2.8e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily 2OG-FeII_Oxy_2 PF13532.6 KFQ91767.1 - 1.4e-29 103.7 0.0 1.7e-29 103.4 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UCH PF00443.29 KFQ91768.1 - 6.3e-43 147.1 0.6 7.3e-43 146.9 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFQ91768.1 - 7.8e-14 52.0 9.4 4e-13 49.6 9.4 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Sugar_tr PF00083.24 KFQ91769.1 - 1.3e-37 129.7 26.8 8e-25 87.6 9.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFQ91769.1 - 1.3e-35 123.0 38.3 4.7e-21 75.1 21.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFQ91769.1 - 0.0046 15.6 19.2 0.017 13.7 1.0 3.4 2 1 1 3 3 3 2 MFS/sugar transport protein DAO PF01266.24 KFQ91770.1 - 1.5e-36 126.7 0.1 1.7e-36 126.5 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Gp_dh_N PF00044.24 KFQ91770.1 - 0.074 13.4 0.0 4.6 7.7 0.0 2.9 3 0 0 3 3 3 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KFQ91770.1 - 0.11 12.1 0.2 0.2 11.2 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 KFQ91770.1 - 0.23 10.7 0.0 2.2 7.5 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain DUF1899 PF08953.11 KFQ91771.1 - 9e-32 108.8 0.0 1.7e-31 107.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KFQ91771.1 - 5.1e-22 77.5 0.1 9.6e-22 76.6 0.1 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KFQ91771.1 - 9.7e-15 54.7 6.9 3.5e-05 24.5 0.6 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ91771.1 - 1.7e-06 28.3 1.1 0.023 15.0 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFQ91771.1 - 0.0096 15.8 0.0 0.029 14.3 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A FIN1 PF17300.2 KFQ91771.1 - 0.03 13.8 2.1 0.043 13.3 2.1 1.2 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 PALB2_WD40 PF16756.5 KFQ91771.1 - 0.11 11.4 0.1 0.18 10.7 0.1 1.4 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain TMEM119 PF15724.5 KFQ91774.1 - 1e-75 255.1 1.9 1.2e-75 254.8 1.9 1.0 1 0 0 1 1 1 1 TMEM119 family DUF4064 PF13273.6 KFQ91774.1 - 0.023 15.0 0.1 0.036 14.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) NICE-3 PF07406.11 KFQ91774.1 - 0.049 13.6 0.1 0.077 13.0 0.1 1.2 1 0 0 1 1 1 0 NICE-3 protein MSP1a PF11670.8 KFQ91774.1 - 0.61 9.3 2.7 2.9 7.1 0.0 2.1 2 0 0 2 2 2 0 Major surface protein 1a (MSP1a) NifU_N PF01592.16 KFQ91775.1 - 3.8e-55 185.5 0.1 4.3e-55 185.3 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain DUF3659 PF12396.8 KFQ91775.1 - 0.084 12.8 0.7 0.34 10.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) Jag_N PF14804.6 KFQ91775.1 - 0.3 11.5 3.5 7.8 6.9 0.1 2.8 3 0 0 3 3 3 0 Jag N-terminus Fic PF02661.18 KFQ91776.1 - 3.6e-28 98.3 0.0 7.4e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 Fic/DOC family TPR_2 PF07719.17 KFQ91776.1 - 0.0011 18.9 0.9 0.016 15.3 0.4 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ91776.1 - 0.044 14.4 0.1 0.1 13.3 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ91776.1 - 0.48 10.1 4.9 1 9.1 0.0 2.9 3 1 1 4 4 4 0 TPR repeat 7tm_1 PF00001.21 KFQ91777.1 - 2.5e-42 145.0 26.6 3.4e-42 144.6 26.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFQ91777.1 - 0.0029 17.3 23.1 0.0029 17.3 23.1 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx WSC PF01822.19 KFQ91778.1 - 6.7e-28 96.7 21.0 1.1e-19 70.4 9.9 2.3 2 0 0 2 2 2 2 WSC domain Sulfotransfer_1 PF00685.27 KFQ91778.1 - 3e-05 23.6 0.0 8.5e-05 22.2 0.0 1.6 1 1 1 2 2 2 1 Sulfotransferase domain Y_phosphatase PF00102.27 KFQ91779.1 - 3e-78 262.6 0.5 3.8e-78 262.3 0.5 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFQ91779.1 - 7.7e-06 25.8 0.1 3.4e-05 23.6 0.1 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFQ91779.1 - 0.00046 20.3 0.5 0.002 18.2 0.0 2.1 2 1 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KFQ91779.1 - 0.0005 20.1 0.1 0.0017 18.4 0.0 2.0 1 1 1 2 2 2 1 Tyrosine phosphatase family Tab2_like PF06485.11 KFQ91779.1 - 0.074 12.5 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 RNA-binding protein Tab2/Atab2 SH2 PF00017.24 KFQ91780.1 - 2.7e-25 88.3 0.0 3.3e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 SH2 domain Ribosomal_L6e PF01159.19 KFQ91781.1 - 8.2e-43 145.5 1.0 8.2e-43 145.5 1.0 2.9 2 1 1 3 3 3 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 KFQ91781.1 - 9.3e-28 96.3 14.3 9.3e-28 96.3 14.3 3.0 3 0 0 3 3 3 1 Ribosomal protein L6, N-terminal domain HECT PF00632.25 KFQ91783.1 - 7.4e-42 143.9 0.0 1.4e-41 143.0 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) NatB_MDM20 PF09797.9 KFQ91784.1 - 2.2e-125 418.6 1.5 2.2e-125 418.6 1.5 2.1 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 KFQ91784.1 - 0.00072 20.0 4.4 0.76 10.3 0.0 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ91784.1 - 0.0018 19.0 8.3 9.2 7.4 0.0 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat BTAD PF03704.17 KFQ91784.1 - 0.058 13.8 1.9 0.78 10.2 0.2 3.1 3 1 1 4 4 4 0 Bacterial transcriptional activator domain TPR_17 PF13431.6 KFQ91784.1 - 0.29 11.6 1.4 1.5e+02 3.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ91784.1 - 0.52 10.6 13.5 7.7 6.8 0.6 4.1 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KFQ91784.1 - 0.8 10.0 6.8 12 6.3 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3510 PF12022.8 KFQ91784.1 - 1.4 9.3 6.3 6.6 7.1 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3510) ERp29_N PF07912.13 KFQ91785.1 - 1.1e-43 148.3 0.2 1.7e-43 147.8 0.2 1.3 1 0 0 1 1 1 1 ERp29, N-terminal domain ERp29 PF07749.12 KFQ91785.1 - 6.3e-18 65.5 5.2 1.1e-17 64.7 5.2 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain PRTase_1 PF11202.8 KFQ91785.1 - 0.011 14.9 1.5 0.018 14.3 1.5 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase (PRTase) GPR_Gpa2_C PF11970.8 KFQ91786.1 - 0.00029 20.9 1.8 0.00068 19.7 1.8 1.6 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Pkinase PF00069.25 KFQ91787.1 - 1.5e-61 208.1 0.0 3.1e-61 207.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ91787.1 - 1.2e-21 77.2 0.1 6.8e-21 74.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KFQ91787.1 - 6.1e-05 22.5 0.2 0.00011 21.6 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFQ91787.1 - 6.8e-05 22.3 0.0 0.00014 21.3 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 KFQ91787.1 - 0.068 12.8 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Aldedh PF00171.22 KFQ91788.1 - 4.9e-185 615.5 0.0 5.5e-185 615.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DtxR PF18357.1 KFQ91788.1 - 0.19 11.4 0.5 0.56 9.9 0.1 1.9 2 0 0 2 2 2 0 Diphteria toxin repressor SH3 domain APH PF01636.23 KFQ91789.1 - 3.6e-41 141.7 0.2 5.3e-41 141.1 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family HAD_2 PF13419.6 KFQ91789.1 - 9.7e-11 42.1 0.0 2.6e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFQ91789.1 - 6.1e-10 39.7 0.0 4e-09 37.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Kdo PF06293.14 KFQ91789.1 - 0.00076 18.9 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 KFQ91789.1 - 0.0045 16.3 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 KFQ91789.1 - 0.034 13.8 0.1 0.79 9.3 0.0 2.3 1 1 1 2 2 2 0 RIO1 family THDPS_N_2 PF14805.6 KFQ91789.1 - 0.19 12.0 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal BRAP2 PF07576.12 KFQ91790.1 - 6.5e-36 122.5 0.8 1.3e-35 121.5 0.8 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KFQ91790.1 - 1.1e-20 73.8 7.1 1.1e-20 73.8 7.1 2.2 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KFQ91790.1 - 1.6e-08 34.8 7.0 1.6e-08 34.8 7.0 2.6 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFQ91790.1 - 9.3e-08 31.8 6.1 9.3e-08 31.8 6.1 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFQ91790.1 - 8.3e-06 26.0 4.7 8.3e-06 26.0 4.7 2.6 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KFQ91790.1 - 1.1e-05 25.0 1.8 1.1e-05 25.0 1.8 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KFQ91790.1 - 2.6e-05 24.1 5.7 2.6e-05 24.1 5.7 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFQ91790.1 - 3.5e-05 23.7 0.5 3.5e-05 23.7 0.5 2.9 1 1 1 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFQ91790.1 - 7.4e-05 22.5 6.2 7.4e-05 22.5 6.2 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KFQ91790.1 - 0.00088 19.1 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-ANAPC11 PF12861.7 KFQ91790.1 - 0.0048 16.9 3.1 0.02 14.9 3.1 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KFQ91790.1 - 0.0061 16.4 18.3 0.031 14.1 7.7 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) KASH_CCD PF14662.6 KFQ91790.1 - 0.015 15.2 26.3 0.026 14.4 26.3 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH FXMRP1_C_core PF12235.8 KFQ91790.1 - 0.029 15.0 6.1 0.04 14.6 0.8 2.5 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal zf-C3H2C3 PF17122.5 KFQ91790.1 - 0.039 14.0 4.2 0.17 11.9 4.2 2.3 1 0 0 1 1 1 0 Zinc-finger V_ATPase_I PF01496.19 KFQ91790.1 - 0.063 11.2 17.0 0.31 8.9 12.7 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 KFQ91790.1 - 0.14 11.3 19.2 0.08 12.0 16.7 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Zn_ribbon_17 PF17120.5 KFQ91790.1 - 0.18 11.4 15.0 0.21 11.2 5.6 2.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Peptidase_S46 PF10459.9 KFQ91790.1 - 0.18 10.4 9.0 0.28 9.8 9.0 1.2 1 0 0 1 1 1 0 Peptidase S46 Baculo_PEP_C PF04513.12 KFQ91790.1 - 0.21 11.6 9.4 0.24 11.4 6.8 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vac_Fusion PF02346.16 KFQ91790.1 - 0.26 10.9 3.6 0.94 9.2 0.8 2.8 1 1 1 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 DUF2935 PF11155.8 KFQ91790.1 - 0.29 11.5 4.7 0.32 11.3 3.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) FapA PF03961.13 KFQ91790.1 - 0.35 9.4 15.2 0.57 8.7 15.2 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A GBP_C PF02841.14 KFQ91790.1 - 0.39 10.1 22.9 0.18 11.2 19.0 2.0 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain FUSC PF04632.12 KFQ91790.1 - 0.41 9.1 1.7 0.59 8.6 1.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family UPF0242 PF06785.11 KFQ91790.1 - 0.57 10.3 24.4 1.1 9.4 24.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Prok-RING_4 PF14447.6 KFQ91790.1 - 0.8 9.6 18.1 0.24 11.3 7.4 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 ADIP PF11559.8 KFQ91790.1 - 0.96 9.5 21.9 2.5 8.2 21.9 1.8 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.12 KFQ91790.1 - 1.2 9.6 8.2 11 6.5 6.4 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CREPT PF16566.5 KFQ91790.1 - 2.3 8.4 20.4 0.85 9.8 12.3 3.0 2 1 1 3 3 2 0 Cell-cycle alteration and expression-elevated protein in tumour Exonuc_VII_L PF02601.15 KFQ91790.1 - 2.4 7.6 11.8 4.1 6.9 11.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 KFQ91790.1 - 3.1 7.0 12.8 5.9 6.0 12.8 1.4 1 0 0 1 1 1 0 TMPIT-like protein KELK PF15796.5 KFQ91790.1 - 3.1 8.3 22.1 1.8 9.1 6.2 3.0 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4407 PF14362.6 KFQ91790.1 - 4 6.7 18.8 0.49 9.7 14.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) eIF3_N PF09440.10 KFQ91790.1 - 4.8 7.6 14.3 4.2 7.8 11.0 2.5 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain DUF4250 PF14056.6 KFQ91790.1 - 7.5 6.6 6.1 3.3 7.7 1.1 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4250) DUF3464 PF11947.8 KFQ91790.1 - 9.4 6.0 6.7 0.35 10.6 0.2 1.9 2 0 0 2 2 1 0 Photosynthesis affected mutant 68 SM-ATX PF14438.6 KFQ91791.1 - 3.1e-21 75.3 0.1 8.1e-21 74.0 0.1 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain LsmAD PF06741.13 KFQ91791.1 - 3.3e-15 56.4 4.8 8.3e-15 55.1 4.8 1.7 1 0 0 1 1 1 1 LsmAD domain PAM2 PF07145.15 KFQ91791.1 - 3.5e-06 26.3 1.0 3.5e-06 26.3 1.0 2.0 2 0 0 2 2 2 1 Ataxin-2 C-terminal region LSM PF01423.22 KFQ91791.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 LSM domain PH PF00169.29 KFQ91792.1 - 1e-19 71.0 0.0 1.5e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFQ91792.1 - 1.8e-05 25.0 0.0 3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFQ91792.1 - 0.0005 20.4 1.2 0.03 14.8 1.2 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 KFQ91792.1 - 0.0058 16.9 0.0 0.0086 16.3 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 KFQ91792.1 - 0.034 13.9 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain PH_4 PF15404.6 KFQ91792.1 - 0.077 12.8 0.1 1.6 8.5 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain CUT PF02376.15 KFQ91793.1 - 1.9e-78 258.6 0.2 1.7e-25 88.9 0.0 3.6 3 0 0 3 3 3 3 CUT domain Homeodomain PF00046.29 KFQ91793.1 - 1e-11 44.5 0.3 4e-11 42.6 0.3 2.2 1 0 0 1 1 1 1 Homeodomain DUF4618 PF15397.6 KFQ91793.1 - 8.9e-06 25.3 16.4 0.0013 18.2 2.9 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4618) DUF5572 PF17733.1 KFQ91793.1 - 0.0099 15.7 0.1 34 4.4 0.0 3.8 3 0 0 3 3 3 0 Family of unknown function (DUF5572) Homeobox_KN PF05920.11 KFQ91793.1 - 0.022 14.7 0.3 0.022 14.7 0.3 3.0 2 0 0 2 2 2 0 Homeobox KN domain DrrA_P4M PF14860.6 KFQ91793.1 - 0.04 13.7 3.0 0.89 9.4 0.0 3.7 3 1 0 3 3 3 0 DrrA phosphatidylinositol 4-phosphate binding domain Phage_connect_1 PF05135.13 KFQ91793.1 - 0.15 12.6 3.9 1.2 9.7 0.1 3.5 3 1 0 3 3 2 0 Phage gp6-like head-tail connector protein Lebercilin PF15619.6 KFQ91793.1 - 0.15 11.7 22.7 0.72 9.5 6.1 3.0 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease FH2 PF02181.23 KFQ91793.1 - 0.58 9.2 10.3 0.027 13.6 2.0 2.4 2 0 0 2 2 2 0 Formin Homology 2 Domain DUF4407 PF14362.6 KFQ91793.1 - 0.6 9.4 27.0 0.14 11.5 16.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) PKcGMP_CC PF16808.5 KFQ91793.1 - 0.65 9.9 10.5 1.6 8.7 1.5 3.8 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase NPV_P10 PF05531.12 KFQ91793.1 - 0.89 10.1 6.5 1.8 9.1 1.6 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 KFQ91793.1 - 1.5 7.6 28.0 2.2 7.1 13.2 2.6 2 0 0 2 2 2 0 Spc7 kinetochore protein Abdominal-A PF12407.8 KFQ91793.1 - 2.1 8.0 7.3 1.7 8.3 2.2 2.8 2 0 0 2 2 2 0 Homeobox protein XLF PF09302.11 KFQ91793.1 - 2.7 8.1 9.7 0.63 10.2 1.7 3.6 3 1 1 4 4 4 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component AAA_13 PF13166.6 KFQ91793.1 - 3.1 6.3 16.1 0.27 9.8 11.3 1.6 2 0 0 2 2 2 0 AAA domain DUF2009 PF09418.10 KFQ91793.1 - 3.6 6.5 10.4 3.5 6.6 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2009) FAM76 PF16046.5 KFQ91793.1 - 5.8 6.2 10.1 3.4 6.9 2.8 2.4 2 0 0 2 2 2 0 FAM76 protein TRAF_BIRC3_bd PF16673.5 KFQ91793.1 - 8.7 6.2 8.2 4.5 7.1 1.8 2.8 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Occludin_ELL PF07303.13 KFQ91793.1 - 9 7.1 10.8 2.4 8.9 3.3 2.9 2 0 0 2 2 2 0 Occludin homology domain EF-hand_1 PF00036.32 KFQ91794.1 - 2e-13 48.9 1.1 5.1e-06 25.7 0.9 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFQ91794.1 - 4.3e-09 35.6 1.4 2e-06 27.2 0.8 3.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 KFQ91794.1 - 1.6e-08 34.3 1.9 0.0024 17.7 0.1 3.9 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_7 PF13499.6 KFQ91794.1 - 7e-08 32.8 0.8 1.8e-05 25.1 0.7 2.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KFQ91794.1 - 0.0017 17.7 1.0 0.0017 17.7 1.0 2.4 2 0 0 2 2 2 1 EF hand Caleosin PF05042.13 KFQ91794.1 - 0.054 13.4 0.2 9.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Caleosin related protein Metallophos PF00149.28 KFQ91796.1 - 4.6e-41 141.6 0.1 5.7e-41 141.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFQ91796.1 - 5.1e-17 62.0 0.9 1.2e-16 60.9 0.5 1.8 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain VGPC1_C PF16799.5 KFQ91797.1 - 2.6e-25 88.1 9.2 4.3e-25 87.4 9.2 1.3 1 0 0 1 1 1 1 C-terminal membrane-localisation domain of ion-channel, VCN1 Ion_trans PF00520.31 KFQ91797.1 - 8.8e-07 28.4 6.6 1.2e-06 28.0 6.6 1.2 1 0 0 1 1 1 1 Ion transport protein PLDc_2 PF13091.6 KFQ91797.1 - 0.051 13.5 0.1 0.093 12.6 0.1 1.4 1 0 0 1 1 1 0 PLD-like domain SP_C-Propep PF08999.10 KFQ91797.1 - 1 9.2 3.7 0.62 9.9 0.1 2.1 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide TMF_DNA_bd PF12329.8 KFQ91797.1 - 2.4 8.2 11.0 0.082 12.9 5.1 1.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CcdA PF07362.12 KFQ91797.1 - 7.1 7.1 6.2 0.37 11.2 0.5 1.7 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA DUF1619 PF07773.11 KFQ91798.1 - 5.2e-85 286.2 6.4 3.7e-82 276.8 3.6 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1619) SpoIIE PF07228.12 KFQ91799.1 - 1.9e-14 54.1 0.0 2.4e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KFQ91799.1 - 2.9e-05 23.8 0.1 0.0088 15.7 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KFQ91799.1 - 0.00054 19.7 0.0 0.00071 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Rad9 PF04139.13 KFQ91800.1 - 4.8e-85 285.0 2.1 6.4e-85 284.6 2.1 1.2 1 0 0 1 1 1 1 Rad9 Metallophos_2 PF12850.7 KFQ91801.1 - 4.9e-22 78.9 0.1 5.7e-22 78.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KFQ91801.1 - 3.2e-05 24.5 1.3 0.12 12.8 0.1 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Rod_C PF10493.9 KFQ91802.1 - 4.3e-261 867.1 9.4 4.3e-261 867.1 9.4 2.6 3 0 0 3 3 3 1 Rough deal protein C-terminal region MRP-S22 PF10245.9 KFQ91802.1 - 0.014 15.2 0.2 0.038 13.7 0.2 1.7 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S22 PSP PF04046.16 KFQ91803.1 - 5.8e-17 61.3 0.2 1.2e-16 60.2 0.2 1.6 1 0 0 1 1 1 1 PSP zf-CCHC PF00098.23 KFQ91803.1 - 2.5e-05 24.1 4.0 4.6e-05 23.3 4.0 1.5 1 0 0 1 1 1 1 Zinc knuckle CAP_GLY PF01302.25 KFQ91804.1 - 8.7e-48 160.2 3.4 2.7e-24 85.0 0.5 2.3 2 0 0 2 2 2 2 CAP-Gly domain CLIP1_ZNF PF16641.5 KFQ91804.1 - 7.2e-15 54.4 20.7 7.1e-09 35.3 4.3 2.4 2 0 0 2 2 2 2 CLIP1 zinc knuckle Fungal_TACC PF12709.7 KFQ91804.1 - 0.0017 18.8 7.0 0.0017 18.8 7.0 15.8 4 3 12 19 19 19 2 Fungal Transforming acidic coiled-coil (TACC) proteins zf-CCHC_4 PF14392.6 KFQ91804.1 - 1.9 8.3 6.7 3.9 7.3 0.3 2.6 2 0 0 2 2 2 0 Zinc knuckle Sec1 PF00995.23 KFQ91805.1 - 3.5e-109 366.6 0.0 4.1e-109 366.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF1629 PF07791.11 KFQ91805.1 - 0.037 14.2 0.0 0.078 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1629) Phage_HK97_TLTM PF06120.11 KFQ91805.1 - 0.11 11.7 0.2 0.16 11.1 0.2 1.2 1 0 0 1 1 1 0 Tail length tape measure protein LRR_8 PF13855.6 KFQ91806.1 - 2.4e-11 43.2 2.0 0.015 15.0 0.8 3.7 2 1 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 KFQ91806.1 - 6.4e-09 35.5 0.2 2.1e-05 24.1 0.0 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 KFQ91806.1 - 3.2e-08 33.8 11.3 0.0048 17.3 0.2 4.0 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFQ91806.1 - 0.00034 20.4 2.6 1.4 9.1 0.1 5.1 6 0 0 6 6 6 1 Leucine Rich repeat LRR_1 PF00560.33 KFQ91806.1 - 0.012 16.1 10.5 10 7.1 0.4 5.4 5 0 0 5 5 5 0 Leucine Rich Repeat HLH PF00010.26 KFQ91807.1 - 1.5e-08 34.4 0.6 3.9e-08 33.1 0.6 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ZapB PF06005.12 KFQ91807.1 - 0.0075 16.7 3.9 0.02 15.4 3.9 1.6 1 0 0 1 1 1 1 Cell division protein ZapB DUF4416 PF14385.6 KFQ91807.1 - 0.017 15.0 0.1 0.036 14.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4416) ATG16 PF08614.11 KFQ91807.1 - 0.02 15.1 2.7 0.043 14.0 2.7 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 KFQ91807.1 - 0.037 13.8 2.8 0.074 12.8 2.8 1.4 1 0 0 1 1 1 0 Septum formation initiator HMMR_C PF15908.5 KFQ91807.1 - 0.04 14.2 0.0 0.088 13.1 0.0 1.5 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal Troponin PF00992.20 KFQ91807.1 - 0.055 13.8 1.5 0.1 12.9 1.5 1.4 1 0 0 1 1 1 0 Troponin TolA_bind_tri PF16331.5 KFQ91807.1 - 0.064 13.3 2.9 0.13 12.4 2.9 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF5082 PF16888.5 KFQ91807.1 - 0.064 13.5 1.5 0.11 12.7 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DUF724 PF05266.14 KFQ91807.1 - 0.11 12.3 0.7 0.19 11.5 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FapA PF03961.13 KFQ91807.1 - 0.15 10.6 0.4 0.22 10.1 0.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Seryl_tRNA_N PF02403.22 KFQ91807.1 - 0.56 10.5 3.4 1.1 9.5 3.4 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain BCL_N PF04714.13 KFQ91808.1 - 1.8e-10 40.7 1.7 4.4e-10 39.5 1.7 1.7 1 0 0 1 1 1 1 BCL7, N-terminal conserver region Defensin_propep PF00879.18 KFQ91808.1 - 0.15 12.3 1.8 0.38 11.1 1.8 1.7 1 0 0 1 1 1 0 Defensin propeptide WD40 PF00400.32 KFQ91809.1 - 2.6e-20 72.4 12.3 0.00024 21.8 0.2 9.6 10 0 0 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ91809.1 - 6.7e-06 26.3 0.0 0.14 12.5 0.0 4.7 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFQ91809.1 - 0.002 17.5 0.0 0.0056 16.0 0.0 1.7 1 1 0 1 1 1 1 WD40-like domain RAB3GAP2_N PF14655.6 KFQ91809.1 - 0.081 12.2 0.2 2.8 7.1 0.0 2.3 1 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Enterotoxin_b PF01376.18 KFQ91809.1 - 0.17 12.1 0.0 3 8.1 0.0 2.7 3 0 0 3 3 3 0 Heat-labile enterotoxin beta chain Nas2_N PF18265.1 KFQ91810.1 - 9.2e-28 96.0 0.1 1.7e-27 95.2 0.1 1.4 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_2 PF13180.6 KFQ91810.1 - 2.4e-10 40.6 0.0 4.5e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFQ91810.1 - 6.3e-09 35.6 0.1 1.1e-08 34.8 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFQ91810.1 - 2.1e-07 31.2 0.2 3.3e-07 30.5 0.2 1.4 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KFQ91810.1 - 5.5e-05 23.5 0.0 7.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain RdgC PF04381.12 KFQ91810.1 - 0.029 13.6 0.6 0.048 12.9 0.6 1.3 1 0 0 1 1 1 0 Putative exonuclease, RdgC Glyoxalase PF00903.25 KFQ91811.1 - 3.7e-23 82.1 0.7 2.5e-14 53.6 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KFQ91811.1 - 3.4e-12 46.6 0.1 2.5e-06 27.7 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KFQ91811.1 - 0.0008 19.6 0.0 2.5 8.2 0.0 3.0 4 0 0 4 4 4 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 KFQ91811.1 - 0.0019 18.4 0.1 0.0052 17.0 0.1 1.7 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal N-SET PF11764.8 KFQ91812.1 - 3.1e-28 99.0 0.0 3.1e-28 99.0 0.0 3.0 2 2 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.28 KFQ91812.1 - 9.4e-17 61.9 2.0 9.4e-17 61.9 2.0 3.2 2 2 0 2 2 2 1 SET domain RRM_1 PF00076.22 KFQ91812.1 - 6.5e-09 35.5 0.1 1.3e-08 34.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFQ91812.1 - 0.016 14.8 0.7 0.13 11.9 0.2 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.22 KFQ91813.1 - 1.5e-51 174.2 0.0 1.8e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ91813.1 - 5.5e-22 78.2 0.0 1.1e-21 77.2 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ91813.1 - 2.2e-09 37.0 0.0 3.1e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFQ91813.1 - 0.005 16.9 0.0 0.0094 16.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 KFQ91813.1 - 0.0071 16.3 0.4 0.81 9.6 0.1 2.7 2 1 1 3 3 3 1 NACHT domain G-alpha PF00503.20 KFQ91813.1 - 0.0073 15.5 0.0 0.013 14.7 0.0 1.5 1 1 0 1 1 1 1 G-protein alpha subunit ABC_tran PF00005.27 KFQ91813.1 - 0.0076 16.8 0.2 0.023 15.2 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SRPRB PF09439.10 KFQ91813.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KFQ91813.1 - 0.018 14.5 0.1 0.099 12.2 0.0 2.0 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain KR PF08659.10 KFQ91813.1 - 0.036 14.0 0.1 0.52 10.2 0.2 2.0 1 1 1 2 2 2 0 KR domain AAA_16 PF13191.6 KFQ91813.1 - 0.055 13.9 0.1 0.11 12.9 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 KFQ91813.1 - 0.056 12.6 0.5 0.65 9.1 0.3 2.2 1 1 1 2 2 2 0 NB-ARC domain Gtr1_RagA PF04670.12 KFQ91813.1 - 0.062 12.6 0.0 0.078 12.3 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 KFQ91813.1 - 0.072 12.6 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KFQ91813.1 - 0.12 12.3 1.7 5.6 6.8 0.2 2.5 1 1 0 2 2 2 0 RsgA GTPase TMPIT PF07851.13 KFQ91814.1 - 2.1e-150 500.5 16.7 2.4e-150 500.3 16.7 1.0 1 0 0 1 1 1 1 TMPIT-like protein Snapin_Pallidin PF14712.6 KFQ91814.1 - 5.9 7.4 6.2 10 6.6 1.8 2.5 2 1 0 2 2 2 0 Snapin/Pallidin MORN PF02493.20 KFQ91815.1 - 1.9e-24 84.0 34.9 0.00018 21.2 0.8 6.8 7 0 0 7 7 7 6 MORN repeat Orai-1 PF07856.12 KFQ91816.1 - 3.1e-55 186.5 2.5 3.5e-55 186.4 2.5 1.0 1 0 0 1 1 1 1 Mediator of CRAC channel activity 7TM_GPCR_Str PF10326.9 KFQ91816.1 - 0.042 13.2 4.5 1.7 7.9 0.4 2.0 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Str m04gp34like PF12216.8 KFQ91816.1 - 0.089 12.4 0.3 1.1 8.8 0.0 2.0 1 1 1 2 2 2 0 Immune evasion protein PHD_4 PF16866.5 KFQ91817.1 - 1e-26 92.8 9.6 1e-26 92.8 9.6 2.6 2 0 0 2 2 1 1 PHD-finger zf-CXXC PF02008.20 KFQ91817.1 - 1.4e-14 53.8 21.5 1.4e-14 53.8 21.5 3.0 2 0 0 2 2 2 1 CXXC zinc finger domain F-box PF00646.33 KFQ91817.1 - 2.2e-13 49.7 6.9 1.1e-12 47.4 1.7 2.8 2 0 0 2 2 2 1 F-box domain JHD PF17811.1 KFQ91817.1 - 4.6e-11 43.2 8.4 2.4e-10 40.9 0.1 3.4 3 0 0 3 3 3 1 Jumonji helical domain F-box-like PF12937.7 KFQ91817.1 - 7.3e-09 35.4 5.8 2e-08 34.0 5.8 1.8 1 0 0 1 1 1 1 F-box-like Cupin_8 PF13621.6 KFQ91817.1 - 5.2e-07 29.6 3.1 1.2e-06 28.5 0.0 2.7 2 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 KFQ91817.1 - 6.6e-05 23.3 0.3 6.6e-05 23.3 0.3 3.6 4 1 0 4 4 3 1 JmjC domain, hydroxylase LRR_6 PF13516.6 KFQ91817.1 - 0.0007 19.5 8.4 31 5.0 0.3 7.1 8 0 0 8 8 8 0 Leucine Rich repeat PHD PF00628.29 KFQ91817.1 - 0.0062 16.4 8.1 0.0062 16.4 8.1 3.0 2 0 0 2 2 1 1 PHD-finger LRR_4 PF12799.7 KFQ91817.1 - 0.11 13.0 7.9 6.3 7.4 0.4 4.2 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFQ91817.1 - 0.82 9.5 4.8 56 3.6 0.1 4.0 4 0 0 4 4 4 0 Leucine rich repeat ANAPC5 PF12862.7 KFQ91818.1 - 5.3e-31 106.6 2.4 5.3e-31 106.6 2.4 3.8 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 KFQ91818.1 - 1.9e-09 37.7 10.6 0.00012 22.3 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ91818.1 - 4.1e-05 24.0 9.2 0.16 12.5 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ91818.1 - 0.00023 20.9 6.5 0.021 14.7 2.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ91818.1 - 0.0003 20.6 6.3 0.1 12.7 0.8 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ91818.1 - 0.0041 17.1 13.2 0.78 10.0 2.2 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ91818.1 - 0.063 14.1 7.7 80 4.5 0.0 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat PriA_C PF18074.1 KFQ91818.1 - 0.39 11.6 2.6 0.77 10.6 0.6 2.8 2 1 0 2 2 1 0 Primosomal protein N C-terminal domain TPR_8 PF13181.6 KFQ91818.1 - 0.68 10.3 7.1 26 5.4 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ91818.1 - 1.8 8.6 7.8 2.5 8.1 1.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ91818.1 - 6.1 7.5 6.2 1.1e+02 3.6 0.4 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 KFQ91819.1 - 3.3e-65 220.1 0.0 2.3e-64 217.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ91819.1 - 4.6e-34 117.9 0.0 4.4e-32 111.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFQ91819.1 - 2.1e-08 33.8 0.0 3.1e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFQ91819.1 - 4.8e-05 22.3 0.0 7.3e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KFQ91819.1 - 0.0073 15.9 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KFQ91819.1 - 0.025 14.5 0.2 0.9 9.4 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family P2X_receptor PF00864.19 KFQ91820.1 - 1.4e-156 521.2 5.0 1.6e-156 521.0 5.0 1.0 1 0 0 1 1 1 1 ATP P2X receptor IFT81_CH PF18383.1 KFQ91821.1 - 1.5e-51 173.8 0.1 1.5e-51 173.8 0.1 3.3 3 0 0 3 3 3 1 Intraflagellar transport 81 calponin homology domain Spc7 PF08317.11 KFQ91821.1 - 0.0013 17.7 20.8 0.0013 17.7 20.8 4.9 1 1 3 5 5 5 3 Spc7 kinetochore protein DUF948 PF06103.11 KFQ91821.1 - 0.022 15.0 10.5 0.18 12.1 0.4 4.2 4 2 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Frankia_peptide PF14407.6 KFQ91821.1 - 0.22 11.6 3.6 1.5 8.9 0.1 3.9 3 1 1 4 4 4 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. P21-Arc PF04062.14 KFQ91822.1 - 2.5e-81 271.9 0.1 2.8e-81 271.7 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit SUI1 PF01253.22 KFQ91823.1 - 4.1e-17 62.5 0.1 7.1e-17 61.7 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 HAP1_N PF04849.13 KFQ91824.1 - 0.0083 15.4 49.6 0.0073 15.5 22.1 3.2 1 1 2 3 3 3 2 HAP1 N-terminal conserved region TMF_TATA_bd PF12325.8 KFQ91824.1 - 0.012 15.9 11.1 0.012 15.9 11.1 4.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding MCPsignal PF00015.21 KFQ91824.1 - 1.2 8.9 4.9 2.9 7.7 0.6 2.4 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CobA_CobO_BtuR PF02572.15 KFQ91824.1 - 1.2 9.3 10.7 0.21 11.8 2.0 2.9 2 2 1 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP DUF3800 PF12686.7 KFQ91824.1 - 3.1 8.4 6.7 24 5.6 6.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) ANTH PF07651.16 KFQ91825.1 - 5.8e-75 251.8 9.2 2.1e-74 250.0 0.1 2.7 2 1 0 2 2 2 1 ANTH domain HIP1_clath_bdg PF16515.5 KFQ91825.1 - 1.8e-30 105.4 23.2 1.8e-30 105.4 23.2 5.6 5 1 0 5 5 5 1 Clathrin-binding domain of Huntingtin-interacting protein 1 I_LWEQ PF01608.17 KFQ91825.1 - 4.5e-22 78.9 1.7 4.5e-22 78.9 1.7 4.7 3 2 0 4 4 4 1 I/LWEQ domain Golgin_A5 PF09787.9 KFQ91825.1 - 0.29 10.6 68.1 0.14 11.6 12.2 4.2 2 1 2 4 4 4 0 Golgin subfamily A member 5 Nup54_57_C PF18570.1 KFQ91825.1 - 0.8 9.3 4.7 1 9.0 0.1 3.4 2 1 0 2 2 2 0 NUP57/Nup54 C-terminal domain DUF3584 PF12128.8 KFQ91825.1 - 2.1 5.8 57.4 0.073 10.6 49.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Mod_r PF07200.13 KFQ91826.1 - 9.8e-33 113.3 8.9 1.3e-32 112.9 8.9 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein TBK1_CCD1 PF18394.1 KFQ91826.1 - 0.032 13.8 0.7 0.042 13.4 0.7 1.1 1 0 0 1 1 1 0 TANK-binding kinase 1 coiled-coil domain 1 7TMR-HDED PF07697.11 KFQ91826.1 - 0.14 12.3 2.5 0.17 12.0 2.5 1.1 1 0 0 1 1 1 0 7TM-HD extracellular Cortex-I_coil PF09304.10 KFQ91826.1 - 0.67 10.2 8.1 2.3 8.5 8.1 1.8 1 1 0 1 1 1 0 Cortexillin I, coiled coil ABC_membrane PF00664.23 KFQ91827.1 - 9.3e-59 199.3 16.7 1.7e-58 198.5 16.7 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFQ91827.1 - 1.4e-34 119.6 0.0 3e-34 118.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFQ91827.1 - 1.2e-10 41.2 1.0 5.1e-07 29.4 0.0 2.3 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KFQ91827.1 - 0.00038 20.4 0.0 0.00088 19.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase ABC_membrane_3 PF13748.6 KFQ91827.1 - 0.00043 19.6 3.6 0.00088 18.6 3.6 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 KFQ91827.1 - 0.00049 20.5 0.1 0.0013 19.1 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFQ91827.1 - 0.00064 20.0 0.0 0.003 17.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KFQ91827.1 - 0.0047 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MCU PF04678.13 KFQ91827.1 - 0.0081 16.3 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial calcium uniporter DUF4191 PF13829.6 KFQ91827.1 - 0.069 12.5 0.1 0.069 12.5 0.1 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4191) SbcCD_C PF13558.6 KFQ91827.1 - 0.16 12.2 0.6 2.6 8.3 0.6 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KFQ91827.1 - 0.18 12.3 0.1 0.62 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KFQ91827.1 - 0.18 11.4 0.5 0.31 10.7 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 KFQ91827.1 - 0.21 12.0 0.5 12 6.3 0.2 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MFS_MOT1 PF16983.5 KFQ91827.1 - 4.2 7.8 9.6 0.73 10.3 1.0 3.0 2 1 1 3 3 3 0 Molybdate transporter of MFS superfamily Integrase_H2C2 PF17921.1 KFQ91828.1 - 3.5e-17 62.2 0.6 5e-17 61.8 0.6 1.2 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFQ91828.1 - 2.2e-06 27.8 0.5 4.2e-06 26.9 0.5 1.4 1 0 0 1 1 1 1 H2C2 zinc finger SR-25 PF10500.9 KFQ91830.1 - 2.8e-88 295.3 65.6 4.5e-88 294.7 65.6 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 KFQ91830.1 - 0.17 10.4 34.8 0.21 10.1 34.8 1.3 1 0 0 1 1 1 0 Macoilin family PI3K_1B_p101 PF10486.9 KFQ91830.1 - 3.5 5.3 34.0 4.3 5.0 34.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DAAD PF18752.1 KFQ91830.1 - 3.9 7.2 13.7 6.4 6.5 13.4 1.5 1 1 0 1 1 1 0 Dictyosteliid AID/APOBEC-like Deaminase CDC27 PF09507.10 KFQ91830.1 - 5.2 6.3 49.9 6.1 6.1 49.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Peptidase_S64 PF08192.11 KFQ91830.1 - 7.9 4.8 36.4 9.5 4.6 36.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 Laminin_I PF06008.14 KFQ91831.1 - 0.0056 16.4 24.8 0.0056 16.4 24.8 2.6 2 0 0 2 2 2 1 Laminin Domain I KASH_CCD PF14662.6 KFQ91831.1 - 0.0082 16.0 20.5 0.0082 16.0 20.5 3.7 2 1 1 3 3 3 1 Coiled-coil region of CCDC155 or KASH Tropomyosin_1 PF12718.7 KFQ91831.1 - 0.012 15.7 40.0 0.025 14.7 19.0 3.5 2 1 1 3 3 2 0 Tropomyosin like DUF1664 PF07889.12 KFQ91831.1 - 0.013 15.6 2.6 0.013 15.6 2.6 3.7 4 1 0 5 5 2 0 Protein of unknown function (DUF1664) Pet100 PF09803.9 KFQ91831.1 - 0.077 13.5 3.7 3.9 8.1 1.0 4.0 3 0 0 3 3 3 0 Pet100 GAS PF13851.6 KFQ91831.1 - 0.079 12.3 40.5 0.1 11.9 12.5 3.5 2 1 1 3 3 2 0 Growth-arrest specific micro-tubule binding PI_PP_C PF18365.1 KFQ91831.1 - 0.093 12.7 4.4 0.13 12.3 2.4 2.3 2 0 0 2 2 2 0 Phosphoinositide phosphatase C-terminal domain RPW8 PF05659.11 KFQ91831.1 - 0.13 11.9 8.6 1.3 8.7 2.3 4.0 2 1 1 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Laminin_II PF06009.12 KFQ91831.1 - 0.26 11.3 21.6 0.081 12.9 4.1 3.6 2 1 1 3 3 2 0 Laminin Domain II Vps51 PF08700.11 KFQ91831.1 - 0.26 11.4 10.9 1.2 9.3 0.9 4.5 3 1 0 3 3 3 0 Vps51/Vps67 ADIP PF11559.8 KFQ91831.1 - 0.7 10.0 42.3 0.31 11.1 9.6 4.4 2 1 2 4 4 3 0 Afadin- and alpha -actinin-Binding Tup_N PF08581.10 KFQ91831.1 - 1.1 9.7 26.4 0.6 10.4 1.1 4.8 3 1 1 4 4 4 0 Tup N-terminal BLOC1_2 PF10046.9 KFQ91831.1 - 1.7 9.0 25.5 9.8 6.6 7.2 4.1 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IFT57 PF10498.9 KFQ91831.1 - 3.2 6.6 36.4 0.084 11.8 15.6 3.2 2 1 1 3 3 2 0 Intra-flagellar transport protein 57 Spc7 PF08317.11 KFQ91831.1 - 3.6 6.4 35.8 0.18 10.6 17.4 3.3 2 1 1 3 3 3 0 Spc7 kinetochore protein Tropomyosin PF00261.20 KFQ91831.1 - 4 6.7 34.5 0.67 9.3 4.2 3.7 2 1 2 4 4 4 0 Tropomyosin Myc-LZ PF02344.15 KFQ91831.1 - 4.1 7.6 6.8 3 8.0 1.0 3.2 3 0 0 3 3 3 0 Myc leucine zipper domain DUF3450 PF11932.8 KFQ91831.1 - 8.1 5.7 21.6 4.2 6.6 7.2 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF745 PF05335.13 KFQ91831.1 - 8.4 6.1 23.0 0.14 11.9 14.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF745) RF-1 PF00472.20 KFQ91832.1 - 5.1e-23 81.2 3.7 5.9e-23 81.0 3.7 1.1 1 0 0 1 1 1 1 RF-1 domain DUF2098 PF09871.9 KFQ91832.1 - 0.085 13.2 2.8 0.11 12.8 2.8 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) Nucleoporin_FG2 PF15967.5 KFQ91832.1 - 0.12 10.9 0.3 0.14 10.6 0.3 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region CDK2AP PF09806.9 KFQ91833.1 - 7.5e-10 39.3 0.0 9.6e-10 38.9 0.0 1.4 1 1 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein AAA_34 PF13872.6 KFQ91834.1 - 1.4e-142 474.0 0.0 2.1e-142 473.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 KFQ91834.1 - 2.3e-125 417.8 0.0 3.5e-125 417.1 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue ResIII PF04851.15 KFQ91834.1 - 1.1e-07 32.1 0.3 7e-07 29.4 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFQ91834.1 - 0.1 13.0 0.1 0.39 11.1 0.1 2.1 1 0 0 1 1 1 0 Helicase conserved C-terminal domain SET PF00856.28 KFQ91835.1 - 1e-19 71.5 1.9 2.9e-19 70.1 0.1 2.3 2 1 0 2 2 2 1 SET domain SRP-alpha_N PF04086.13 KFQ91835.1 - 0.23 11.3 8.5 0.3 11.0 8.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RILP PF11461.8 KFQ91836.1 - 2.1e-21 75.9 3.6 2.1e-21 75.9 3.6 1.8 2 0 0 2 2 2 1 Rab interacting lysosomal protein Jnk-SapK_ap_N PF09744.9 KFQ91836.1 - 3.2e-05 24.2 3.1 0.00044 20.5 0.1 2.2 2 0 0 2 2 2 2 JNK_SAPK-associated protein-1 DUF4691 PF15762.5 KFQ91836.1 - 0.037 14.2 1.2 0.073 13.2 1.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4691) RRM_1 PF00076.22 KFQ91837.1 - 1.1e-17 63.6 0.1 1.9e-17 62.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_ligase_IV PF11411.8 KFQ91837.1 - 0.063 13.4 0.0 0.71 10.0 0.0 2.2 2 0 0 2 2 2 0 DNA ligase IV RILP PF11461.8 KFQ91838.1 - 7.5e-21 74.1 4.4 7.5e-21 74.1 4.4 3.1 2 1 1 3 3 3 1 Rab interacting lysosomal protein Jnk-SapK_ap_N PF09744.9 KFQ91838.1 - 3.3e-13 50.1 8.1 3.3e-13 50.1 8.1 3.4 2 1 2 4 4 3 1 JNK_SAPK-associated protein-1 Leu_zip PF15294.6 KFQ91838.1 - 0.0047 16.5 10.6 0.0047 16.5 10.6 2.5 1 1 1 2 2 2 1 Leucine zipper sCache_like PF16736.5 KFQ91838.1 - 0.015 15.4 2.9 0.015 15.4 2.9 2.7 1 1 2 3 3 3 0 Single Cache-like Spc42p PF11544.8 KFQ91838.1 - 0.048 13.7 1.1 0.048 13.7 1.1 4.5 4 1 0 5 5 5 0 Spindle pole body component Spc42p TSC22 PF01166.18 KFQ91838.1 - 0.066 13.5 0.8 0.066 13.5 0.8 4.3 4 1 1 5 5 5 0 TSC-22/dip/bun family YflT PF11181.8 KFQ91838.1 - 0.067 13.7 4.1 0.07 13.6 2.1 2.2 2 1 0 2 2 2 0 Heat induced stress protein YflT FGAR-AT_linker PF18072.1 KFQ91838.1 - 0.17 12.4 1.6 25 5.5 0.0 3.2 2 1 1 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase linker domain DUF4407 PF14362.6 KFQ91838.1 - 0.4 10.0 16.9 2 7.7 15.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HrpB7 PF09486.10 KFQ91838.1 - 3.2 8.1 14.8 2.1 8.7 1.4 2.8 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) SOGA PF11365.8 KFQ91838.1 - 4.8 8.4 27.6 1.1 10.5 8.4 3.6 1 1 1 3 3 3 0 Protein SOGA EMP24_GP25L PF01105.24 KFQ91839.1 - 2.2e-39 135.3 0.1 2.5e-39 135.1 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TerD PF02342.18 KFQ91839.1 - 0.0005 19.6 0.2 0.00061 19.3 0.2 1.1 1 0 0 1 1 1 1 TerD domain Innexin PF00876.18 KFQ91839.1 - 0.033 13.5 0.3 0.038 13.3 0.3 1.1 1 0 0 1 1 1 0 Innexin SdrD_B PF17210.3 KFQ91839.1 - 0.036 14.3 0.3 0.089 13.0 0.3 1.7 1 1 0 1 1 1 0 SdrD B-like domain DUF1104 PF06518.11 KFQ91839.1 - 0.12 12.8 1.6 0.22 11.9 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) DEAD PF00270.29 KFQ91840.1 - 1.5e-41 142.0 0.0 3.4e-41 140.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFQ91840.1 - 6.7e-24 84.4 0.0 3.7e-22 78.8 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFQ91840.1 - 7e-23 80.6 0.6 1.8e-22 79.3 0.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KFQ91840.1 - 2.4e-07 30.9 1.1 2.2e-06 27.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SBF_like PF13593.6 KFQ91840.1 - 0.0076 15.6 0.0 0.01 15.2 0.0 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) AAA_22 PF13401.6 KFQ91840.1 - 0.023 15.0 0.1 0.078 13.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain Helicase_C_2 PF13307.6 KFQ91840.1 - 0.066 13.4 1.9 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 Helicase C-terminal domain SurA_N_3 PF13624.6 KFQ91840.1 - 0.07 12.9 4.4 0.14 12.0 4.4 1.4 1 0 0 1 1 1 0 SurA N-terminal domain SHOCT PF09851.9 KFQ91840.1 - 6.4 6.7 10.8 0.078 12.7 0.7 3.0 3 0 0 3 3 3 0 Short C-terminal domain IF-2B PF01008.17 KFQ91841.1 - 3.2e-77 259.5 0.0 3.6e-77 259.3 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family SPC12 PF06645.13 KFQ91841.1 - 0.1 12.7 0.1 0.41 10.8 0.0 1.9 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Tfb4 PF03850.14 KFQ91842.1 - 1.1e-101 340.0 0.2 1.3e-101 339.8 0.2 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Baculo_IE-1 PF05290.11 KFQ91842.1 - 2 8.4 8.2 0.74 9.8 4.9 1.9 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) DUF1619 PF07773.11 KFQ91843.1 - 8.6e-60 203.3 4.2 1.4e-58 199.3 3.9 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1619) V_ATPase_I PF01496.19 KFQ91844.1 - 7.2e-290 963.6 0.1 8.2e-290 963.4 0.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family SKA2 PF16740.5 KFQ91844.1 - 0.017 14.9 0.2 0.044 13.6 0.2 1.6 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 CENP-F_leu_zip PF10473.9 KFQ91844.1 - 0.018 15.1 3.5 0.082 12.9 1.0 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.6 KFQ91844.1 - 0.018 14.8 2.5 0.038 13.7 2.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Spc24 PF08286.11 KFQ91844.1 - 0.16 12.3 0.2 0.33 11.2 0.2 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Takusan PF04822.13 KFQ91844.1 - 1.3 9.0 6.6 0.26 11.2 2.7 1.8 2 0 0 2 2 2 0 Takusan DUF4404 PF14357.6 KFQ91844.1 - 1.3 9.8 7.2 5.2 7.8 2.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) DHR10 PF18595.1 KFQ91844.1 - 2.7 8.1 10.5 0.17 11.9 3.4 2.4 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain DUF4200 PF13863.6 KFQ91844.1 - 4.9 7.6 8.4 28 5.1 6.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Med21 PF11221.8 KFQ91844.1 - 5.8 7.2 7.8 3.3 8.0 5.5 1.7 2 1 0 2 2 2 0 Subunit 21 of Mediator complex DHC_N1 PF08385.12 KFQ91845.1 - 8.7e-160 533.0 13.3 8.7e-160 533.0 13.3 3.5 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 KFQ91845.1 - 1.5e-158 527.0 0.0 3.1e-156 519.4 0.0 3.4 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KFQ91845.1 - 8e-126 420.3 8.8 8e-126 420.3 8.8 5.5 7 0 0 7 7 7 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KFQ91845.1 - 2.5e-99 331.8 0.0 8.6e-99 330.1 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KFQ91845.1 - 1.5e-83 279.3 1.1 1.5e-83 279.3 1.1 3.6 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 KFQ91845.1 - 5.9e-74 247.5 4.2 6.5e-69 231.1 0.1 3.8 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KFQ91845.1 - 7.9e-55 185.1 0.1 2.1e-54 183.7 0.1 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KFQ91845.1 - 1.4e-47 162.4 14.4 2.8e-47 161.4 14.4 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KFQ91845.1 - 3e-41 140.2 0.0 1.2e-39 135.0 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KFQ91845.1 - 3e-25 88.8 5.7 1.6e-07 31.4 0.0 6.4 6 1 0 6 6 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KFQ91845.1 - 1e-19 70.6 0.1 7e-19 67.9 0.1 2.6 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 KFQ91845.1 - 3e-18 66.1 0.0 1.6e-17 63.8 0.0 2.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 KFQ91845.1 - 3.7e-09 37.0 0.1 0.038 14.3 0.0 5.6 4 0 0 4 4 4 2 AAA domain AAA PF00004.29 KFQ91845.1 - 5.1e-08 33.4 0.0 0.61 10.5 0.0 5.5 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFQ91845.1 - 5.7e-07 30.1 0.1 3.4 8.0 0.0 5.9 4 1 1 5 5 5 2 AAA ATPase domain RsgA_GTPase PF03193.16 KFQ91845.1 - 8.1e-05 22.6 0.1 0.005 16.8 0.0 3.5 3 0 0 3 3 3 1 RsgA GTPase RNA_helicase PF00910.22 KFQ91845.1 - 0.00013 22.3 0.0 4.6 7.7 0.0 3.9 3 0 0 3 3 3 1 RNA helicase AAA_18 PF13238.6 KFQ91845.1 - 0.00014 22.4 0.0 0.11 13.0 0.0 4.7 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KFQ91845.1 - 0.00095 19.4 0.3 28 4.9 0.1 4.7 4 0 0 4 4 4 0 AAA domain Sigma54_activat PF00158.26 KFQ91845.1 - 0.0017 18.1 0.1 3.5 7.3 0.0 3.4 3 0 0 3 3 3 1 Sigma-54 interaction domain T2SSE PF00437.20 KFQ91845.1 - 0.0049 16.0 1.0 0.64 9.0 0.1 2.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.6 KFQ91845.1 - 0.018 14.8 0.0 1.6 8.5 0.0 2.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KFQ91845.1 - 0.05 14.1 2.0 3.2 8.3 0.1 4.4 4 0 0 4 4 3 0 ABC transporter FtsK_SpoIIIE PF01580.18 KFQ91845.1 - 0.087 12.2 0.1 2.5 7.4 0.0 2.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family SMC_N PF02463.19 KFQ91845.1 - 0.17 11.3 0.0 2.5 7.5 0.0 2.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_19 PF13245.6 KFQ91845.1 - 0.44 10.9 2.9 77 3.6 0.1 4.0 3 0 0 3 3 3 0 AAA domain CCDC92 PF14916.6 KFQ91846.1 - 3e-24 84.5 8.6 1.7e-22 78.9 1.8 2.7 2 0 0 2 2 2 2 Coiled-coil domain of unknown function Angiomotin_C PF12240.8 KFQ91846.1 - 0.0017 18.0 8.6 0.002 17.7 7.4 1.7 1 1 1 2 2 2 1 Angiomotin C terminal Sigma54_DBD PF04552.13 KFQ91846.1 - 0.0056 16.4 2.6 0.01 15.6 2.6 1.4 1 0 0 1 1 1 1 Sigma-54, DNA binding domain CENP-F_leu_zip PF10473.9 KFQ91846.1 - 0.017 15.2 23.3 0.43 10.6 0.8 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Exonuc_VII_L PF02601.15 KFQ91846.1 - 0.18 11.3 8.5 0.28 10.7 8.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mei5 PF10376.9 KFQ91846.1 - 0.37 10.6 16.5 0.15 11.9 12.6 1.9 1 1 1 2 2 2 0 Double-strand recombination repair protein DUF3584 PF12128.8 KFQ91846.1 - 0.42 8.1 13.0 0.55 7.7 13.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4407 PF14362.6 KFQ91846.1 - 0.49 9.7 6.1 0.96 8.7 6.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4618 PF15397.6 KFQ91846.1 - 0.56 9.6 19.0 0.47 9.8 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) TPR_MLP1_2 PF07926.12 KFQ91846.1 - 0.67 10.0 21.9 0.28 11.2 0.4 3.2 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.11 KFQ91846.1 - 0.9 9.3 16.6 1.6 8.5 0.3 2.8 1 1 1 2 2 2 0 Phage minor structural protein GP20 Atg14 PF10186.9 KFQ91846.1 - 1.1 8.3 17.9 9.1 5.3 17.9 2.0 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlxA PF14282.6 KFQ91846.1 - 2.4 8.2 15.3 2.2 8.3 3.3 3.3 1 1 3 4 4 4 0 FlxA-like protein Fez1 PF06818.15 KFQ91846.1 - 2.5 8.5 17.4 2.3 8.6 13.8 2.1 1 1 1 2 2 2 0 Fez1 Syntaxin-6_N PF09177.11 KFQ91846.1 - 2.6 8.6 9.8 1.1e+02 3.5 9.8 2.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Nup54 PF13874.6 KFQ91846.1 - 2.8 8.1 16.4 0.12 12.5 5.8 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 V_ATPase_I PF01496.19 KFQ91846.1 - 5.9 4.7 8.6 7.6 4.3 8.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Golgin_A5 PF09787.9 KFQ91846.1 - 6.6 6.1 18.9 4.3 6.7 0.5 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 5 Prominin PF05478.11 KFQ91846.1 - 7.2 4.4 9.7 9.2 4.1 9.7 1.1 1 0 0 1 1 1 0 Prominin KxDL PF10241.9 KFQ91846.1 - 7.4 6.9 16.7 1.6 9.1 7.5 2.6 2 1 1 3 3 3 0 Uncharacterized conserved protein FAM101 PF15068.6 KFQ91847.1 - 1.3e-68 231.0 1.2 1.5e-68 230.8 1.2 1.0 1 0 0 1 1 1 1 FAM101 family DUF3915 PF13054.6 KFQ91848.1 - 0.19 11.7 2.4 0.51 10.3 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) CD36 PF01130.21 KFQ91849.1 - 7.2e-146 486.4 0.1 8.4e-146 486.2 0.1 1.0 1 0 0 1 1 1 1 CD36 family ubiquitin PF00240.23 KFQ91850.1 - 2.7e-105 344.2 10.1 2.7e-34 116.8 0.3 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 KFQ91850.1 - 4.2e-51 170.7 10.7 2.8e-16 59.1 0.4 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFQ91850.1 - 2.3e-20 72.9 3.3 6.9e-05 23.2 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 KFQ91850.1 - 1.1e-12 47.6 1.7 0.014 15.3 0.1 3.2 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KFQ91850.1 - 7.2e-12 45.4 1.0 0.043 13.9 0.0 4.0 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KFQ91850.1 - 1.5e-11 44.5 2.9 0.029 14.7 0.1 3.1 3 0 0 3 3 3 3 Ubiquitin-like domain DUF2407 PF10302.9 KFQ91850.1 - 2.9e-09 37.4 0.1 0.37 11.4 0.0 3.2 1 1 1 3 3 3 3 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 KFQ91850.1 - 1.7e-06 28.0 0.0 1.6 8.5 0.0 3.1 1 1 2 3 3 3 3 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 KFQ91850.1 - 4e-06 26.8 14.1 17 5.6 0.0 6.0 6 0 0 6 6 6 0 Ubiquitin-like domain DUF2870 PF11069.8 KFQ91850.1 - 0.00024 21.4 0.1 20 5.7 0.0 3.8 3 3 0 3 3 3 0 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.14 KFQ91850.1 - 0.0007 19.0 0.1 1.2 8.5 0.0 2.3 2 0 0 2 2 2 2 RNA methyltransferase RBD PF02196.15 KFQ91850.1 - 0.00075 19.5 0.0 22 5.2 0.0 3.3 3 0 0 3 3 3 0 Raf-like Ras-binding domain DUF3861 PF12977.7 KFQ91850.1 - 0.0017 18.5 0.2 26 5.1 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) UDP-g_GGTase PF06427.11 KFQ91850.1 - 0.0018 18.4 2.0 3.4 7.8 0.0 3.2 4 0 0 4 4 3 2 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 KFQ91850.1 - 0.0077 15.7 0.0 14 5.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF969) FlgD_ig PF13860.6 KFQ91850.1 - 0.019 14.8 2.4 39 4.2 0.1 3.4 3 0 0 3 3 3 0 FlgD Ig-like domain Big_7 PF17957.1 KFQ91850.1 - 0.02 15.6 0.0 89 4.0 0.0 3.1 3 0 0 3 3 3 0 Bacterial Ig domain GDYXXLXY PF14345.6 KFQ91850.1 - 0.052 13.3 0.1 75 3.1 0.0 3.3 3 0 0 3 3 3 0 GDYXXLXY protein CorA PF01544.18 KFQ91850.1 - 0.058 12.7 0.1 51 3.0 0.0 3.0 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein ORF11CD3 PF10549.9 KFQ91850.1 - 0.062 13.4 0.0 61 3.8 0.0 3.7 3 0 0 3 3 3 0 ORF11CD3 domain TraK PF06586.11 KFQ91850.1 - 0.068 12.9 0.1 59 3.2 0.0 3.1 3 0 0 3 3 3 0 TraK protein Phage_sheath_1N PF17481.2 KFQ91850.1 - 0.069 13.6 1.7 22 5.6 0.3 3.0 1 1 0 2 2 2 0 Phage tail sheath protein beta-sandwich domain ProRS-C_2 PF09181.10 KFQ91850.1 - 0.084 13.0 1.1 88 3.3 0.0 3.1 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal DMA PF03474.14 KFQ91850.1 - 0.42 10.3 1.7 1.1e+02 2.5 0.0 3.3 3 0 0 3 3 3 0 DMRTA motif PI3K_p85B PF02192.16 KFQ91850.1 - 1.3 8.8 3.4 1.1e+02 2.6 0.1 3.2 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain DUF4257 PF14074.6 KFQ91851.1 - 3.2e-05 24.0 0.0 0.44 10.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4257) TM1506 PF08973.10 KFQ91851.1 - 0.0056 16.4 0.0 3.8 7.2 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1893) Glyco_hydro_67N PF03648.14 KFQ91851.1 - 0.13 12.6 0.1 23 5.3 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 67 N-terminus stn_TNFRSF12A PF12191.8 KFQ91851.1 - 1.3 9.2 5.3 47 4.2 0.1 3.2 3 0 0 3 3 3 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain OB_NTP_bind PF07717.16 KFQ91852.1 - 3.8e-24 84.9 0.0 8.5e-24 83.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KFQ91852.1 - 6.2e-24 84.4 0.0 6.2e-24 84.4 0.0 3.0 3 0 0 3 3 3 1 Helicase associated domain (HA2) DEAD PF00270.29 KFQ91852.1 - 9.7e-12 45.0 0.1 9.7e-12 45.0 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFQ91852.1 - 3e-10 40.4 0.1 2.1e-08 34.5 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFQ91852.1 - 7.4e-07 29.5 0.0 4.8e-06 26.9 0.0 2.4 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 KFQ91852.1 - 1.7e-05 24.6 0.0 4.9e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFQ91852.1 - 1.9e-05 25.0 0.0 5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 KFQ91852.1 - 0.003 17.6 1.5 0.039 13.9 0.0 3.0 3 0 0 3 3 3 1 Flavivirus DEAD domain T2SSE PF00437.20 KFQ91852.1 - 0.0054 15.8 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 KFQ91852.1 - 0.0069 15.8 0.0 0.016 14.5 0.0 1.6 1 0 0 1 1 1 1 KaiC ABC_tran PF00005.27 KFQ91852.1 - 0.027 15.0 4.0 0.42 11.1 0.1 2.8 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 KFQ91852.1 - 0.034 14.7 0.5 0.034 14.7 0.5 3.2 2 2 0 2 2 1 0 AAA domain DUF2075 PF09848.9 KFQ91852.1 - 0.038 13.2 0.0 0.038 13.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KFQ91852.1 - 0.062 13.3 6.4 0.081 12.9 0.4 3.2 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.16 KFQ91852.1 - 0.11 11.9 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Roc PF08477.13 KFQ91852.1 - 0.14 12.4 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase BRI3BP PF14965.6 KFQ91853.1 - 2.1e-65 219.6 1.0 2.4e-65 219.4 1.0 1.0 1 0 0 1 1 1 1 Negative regulator of p53/TP53 CLZ PF16526.5 KFQ91853.1 - 0.028 14.7 0.0 0.052 13.9 0.0 1.3 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MgtE PF01769.16 KFQ91853.1 - 0.033 14.6 2.8 0.048 14.1 2.8 1.4 1 0 0 1 1 1 0 Divalent cation transporter AMP-binding PF00501.28 KFQ91854.1 - 4.2e-43 147.5 0.0 6.3e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KFQ91854.1 - 8.3e-11 41.6 2.4 8.3e-11 41.6 2.4 1.7 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus TMEM132D_N PF15705.5 KFQ91855.1 - 6e-57 191.1 0.0 1e-56 190.4 0.0 1.4 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term TMEM132 PF16070.5 KFQ91855.1 - 1.3e-16 60.9 3.3 2.1e-16 60.2 3.3 1.4 1 0 0 1 1 1 1 Transmembrane protein family 132 TMEM132 PF16070.5 KFQ91856.1 - 4.2e-125 417.6 1.0 5.3e-125 417.3 1.0 1.1 1 0 0 1 1 1 1 Transmembrane protein family 132 TMEM132D_C PF15706.5 KFQ91856.1 - 9.7e-34 115.0 0.0 2.3e-33 113.8 0.0 1.7 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TMEM132D_N PF15705.5 KFQ91857.1 - 4.4e-58 194.8 0.1 5.1e-58 194.6 0.1 1.0 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term TMEM132 PF16070.5 KFQ91858.1 - 8.4e-153 508.7 4.7 1.4e-152 508.0 4.7 1.4 1 0 0 1 1 1 1 Transmembrane protein family 132 TMEM132D_C PF15706.5 KFQ91858.1 - 5.4e-38 128.7 0.0 1.1e-37 127.7 0.0 1.6 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term PTR2 PF00854.21 KFQ91859.1 - 1e-113 380.2 7.4 1.3e-113 379.9 7.4 1.0 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 KFQ91859.1 - 7.9e-10 38.2 11.4 1.6e-09 37.2 11.4 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Glycos_transf_1 PF00534.20 KFQ91860.1 - 2.1e-20 73.0 0.0 3.1e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFQ91860.1 - 1e-15 58.4 0.0 1.7e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KFQ91860.1 - 3.5e-08 33.7 0.0 7.6e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 TMEM132 PF16070.5 KFQ91861.1 - 8.6e-156 518.6 2.2 1.1e-155 518.2 2.2 1.2 1 0 0 1 1 1 1 Transmembrane protein family 132 TMEM132D_C PF15706.5 KFQ91861.1 - 7e-36 121.9 0.0 1.6e-35 120.7 0.0 1.7 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TMEM132D_N PF15705.5 KFQ91862.1 - 3.8e-60 201.5 0.1 4.4e-60 201.3 0.1 1.0 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term Frizzled PF01534.17 KFQ91863.1 - 4.7e-139 463.0 22.8 6.2e-139 462.6 22.8 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 KFQ91863.1 - 1.4e-33 115.8 7.1 3.6e-33 114.5 7.1 1.7 1 0 0 1 1 1 1 Fz domain Piwi PF02171.17 KFQ91864.1 - 1e-105 353.3 0.0 1.5e-105 352.8 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 KFQ91864.1 - 1.1e-35 122.5 0.2 2.6e-35 121.2 0.2 1.6 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 KFQ91864.1 - 4e-08 34.0 0.0 1.2e-07 32.4 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KFQ91864.1 - 3.3e-05 23.5 0.0 9e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain GAGE PF05831.11 KFQ91864.1 - 0.00014 22.3 3.6 0.00032 21.2 3.6 1.6 1 0 0 1 1 1 1 GAGE protein ArgoL2 PF16488.5 KFQ91864.1 - 0.098 13.0 0.3 0.36 11.2 0.0 2.1 2 0 0 2 2 2 0 Argonaute linker 2 domain Calici_coat PF00915.20 KFQ91864.1 - 0.098 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Calicivirus coat protein SH3_2 PF07653.17 KFQ91865.1 - 1.3e-32 111.2 0.0 2.1e-10 40.1 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_9 PF14604.6 KFQ91865.1 - 1.1e-27 95.7 3.4 3.6e-12 45.9 0.1 3.8 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 KFQ91865.1 - 4.1e-16 58.3 0.1 2e-06 27.3 0.0 3.9 3 1 0 3 3 3 3 SH3 domain fn3 PF00041.21 KFQ91865.1 - 2.1e-13 50.4 4.7 0.0003 21.1 0.2 4.2 3 1 0 3 3 3 3 Fibronectin type III domain DUF4527 PF15030.6 KFQ91865.1 - 1.5 8.2 10.7 3.5 7.0 10.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) DUF16 PF01519.16 KFQ91865.1 - 4.9 7.7 6.2 15 6.2 6.2 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF16 ADIP PF11559.8 KFQ91865.1 - 5.5 7.1 12.1 11 6.1 12.1 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Syntaxin PF00804.25 KFQ91866.1 - 1.6e-62 210.7 17.1 1.6e-62 210.7 17.1 1.7 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 KFQ91866.1 - 3.3e-19 68.6 2.1 3.3e-19 68.6 2.1 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 KFQ91866.1 - 1.1e-11 45.0 6.5 1.1e-11 45.0 6.5 2.6 2 2 0 2 2 2 1 Syntaxin-like protein DUF3671 PF12420.8 KFQ91866.1 - 0.00081 19.4 0.8 0.00081 19.4 0.8 2.1 2 0 0 2 2 1 1 Protein of unknown function T2SSF PF00482.23 KFQ91866.1 - 0.0017 18.3 4.8 0.015 15.3 0.6 2.7 2 1 0 2 2 2 1 Type II secretion system (T2SS), protein F COG5 PF10392.9 KFQ91866.1 - 0.0021 18.3 8.1 0.19 11.9 0.8 2.7 2 1 0 2 2 2 2 Golgi transport complex subunit 5 Prominin PF05478.11 KFQ91866.1 - 0.0021 16.1 2.5 0.0021 16.1 2.5 2.1 1 1 0 2 2 2 1 Prominin FapA PF03961.13 KFQ91866.1 - 0.0024 16.6 8.2 0.0024 16.6 8.2 2.1 1 1 0 2 2 2 1 Flagellar Assembly Protein A DUF1640 PF07798.11 KFQ91866.1 - 0.0032 17.5 3.3 0.0032 17.5 3.3 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1640) DUF677 PF05055.12 KFQ91866.1 - 0.011 14.6 14.6 0.011 14.7 3.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF677) DUF16 PF01519.16 KFQ91866.1 - 0.013 16.0 0.7 0.013 16.0 0.7 3.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 AAA_27 PF13514.6 KFQ91866.1 - 0.013 15.1 5.1 0.22 11.1 0.6 2.1 2 0 0 2 2 2 0 AAA domain Syntaxin-6_N PF09177.11 KFQ91866.1 - 0.018 15.6 2.1 0.018 15.6 2.1 3.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.12 KFQ91866.1 - 0.029 14.4 2.2 0.42 10.6 0.2 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4855 PF16147.5 KFQ91866.1 - 0.038 13.1 0.4 0.038 13.1 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4855) DUF1845 PF08900.11 KFQ91866.1 - 0.053 13.3 0.1 0.053 13.3 0.1 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF1845) Lipase_GDSL PF00657.22 KFQ91866.1 - 0.1 12.6 3.4 0.16 11.9 3.4 1.8 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase DUF2205 PF10224.9 KFQ91866.1 - 0.14 12.1 0.3 0.14 12.1 0.3 3.8 4 0 0 4 4 4 0 Short coiled-coil protein LPP PF04728.13 KFQ91866.1 - 0.19 12.1 10.2 9.3 6.7 0.2 3.7 3 1 0 3 3 3 0 Lipoprotein leucine-zipper AAA_13 PF13166.6 KFQ91866.1 - 0.22 10.1 21.4 0.56 8.8 20.0 1.8 1 1 1 2 2 2 0 AAA domain Nas2_N PF18265.1 KFQ91866.1 - 0.27 11.2 5.6 1.1 9.2 0.0 3.5 3 1 0 3 3 3 0 Nas2 N_terminal domain YtxH PF12732.7 KFQ91866.1 - 0.32 11.5 4.8 2.8 8.5 0.2 3.1 2 1 1 3 3 3 0 YtxH-like protein TipAS PF07739.13 KFQ91866.1 - 0.34 11.5 5.1 7.2 7.2 0.4 2.7 2 2 0 2 2 2 0 TipAS antibiotic-recognition domain Serine_rich PF08824.10 KFQ91866.1 - 0.34 10.9 4.2 0.45 10.5 0.7 2.3 2 0 0 2 2 2 0 Serine rich protein interaction domain Mer2 PF09074.10 KFQ91866.1 - 0.39 10.5 17.1 0.032 14.1 2.5 2.7 1 1 1 2 2 2 0 Mer2 YscO PF07321.12 KFQ91866.1 - 0.81 9.6 0.1 0.81 9.6 0.1 3.5 3 2 0 3 3 3 0 Type III secretion protein YscO FH2 PF02181.23 KFQ91866.1 - 0.95 8.5 14.8 1.9 7.5 1.7 3.1 2 1 0 3 3 3 0 Formin Homology 2 Domain K-box PF01486.17 KFQ91866.1 - 1.1 9.5 10.7 0.21 11.8 3.8 2.8 2 2 0 2 2 2 0 K-box region DUF745 PF05335.13 KFQ91866.1 - 1.2 8.9 10.0 5 6.8 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF2207 PF09972.9 KFQ91866.1 - 1.2 7.8 6.2 0.17 10.6 0.5 1.9 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) NPV_P10 PF05531.12 KFQ91866.1 - 1.2 9.6 5.0 22 5.6 1.5 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TSC22 PF01166.18 KFQ91866.1 - 1.5 9.2 8.5 2.4 8.5 0.1 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family FlaC_arch PF05377.11 KFQ91866.1 - 1.7 9.1 13.9 4.8 7.6 0.3 4.4 3 1 0 4 4 4 0 Flagella accessory protein C (FlaC) Sec34 PF04136.15 KFQ91866.1 - 1.8 8.4 12.4 0.31 10.9 3.2 2.9 2 1 1 3 3 3 0 Sec34-like family MCPsignal PF00015.21 KFQ91866.1 - 1.9 8.3 14.0 1.3 8.9 0.7 3.4 1 1 3 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain WXG100 PF06013.12 KFQ91866.1 - 2 8.7 8.3 12 6.2 0.2 3.8 4 1 0 4 4 3 0 Proteins of 100 residues with WXG Mur_ligase_M PF08245.12 KFQ91866.1 - 2.2 8.2 9.1 1.4 8.9 1.5 2.5 2 1 0 2 2 2 0 Mur ligase middle domain DUF848 PF05852.11 KFQ91866.1 - 2.5 8.2 14.7 0.093 12.8 4.6 2.6 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) TMPIT PF07851.13 KFQ91866.1 - 2.7 7.2 14.4 1.3 8.3 3.0 2.3 1 1 0 2 2 2 0 TMPIT-like protein Allexi_40kDa PF05549.11 KFQ91866.1 - 3 7.3 10.8 0.69 9.4 2.1 2.3 1 1 0 2 2 2 0 Allexivirus 40kDa protein DUF1664 PF07889.12 KFQ91866.1 - 3.3 7.8 15.2 28 4.8 3.1 3.9 2 2 0 3 3 3 0 Protein of unknown function (DUF1664) FlgN PF05130.12 KFQ91866.1 - 5.4 7.5 12.1 0.62 10.6 4.7 2.5 1 1 2 3 3 3 0 FlgN protein DUF4199 PF13858.6 KFQ91866.1 - 6.8 7.1 10.9 0.11 12.8 1.6 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF4199) MCU PF04678.13 KFQ91866.1 - 6.9 6.7 12.8 3.7 7.6 2.4 2.4 1 1 0 2 2 2 0 Mitochondrial calcium uniporter FlxA PF14282.6 KFQ91866.1 - 7.2 6.7 11.5 0.69 9.9 3.2 2.8 2 1 0 2 2 2 0 FlxA-like protein Alanine_zipper PF11839.8 KFQ91866.1 - 8.7 6.8 7.5 2.2 8.7 0.2 2.7 3 0 0 3 3 2 0 Alanine-zipper, major outer membrane lipoprotein PCRF PF03462.18 KFQ91866.1 - 9.5 6.0 17.8 1.4 8.7 2.4 2.8 1 1 2 3 3 3 0 PCRF domain Ras PF00071.22 KFQ91867.1 - 5.9e-50 169.0 0.0 7e-50 168.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ91867.1 - 4.2e-31 107.6 0.0 8.4e-31 106.7 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ91867.1 - 1.4e-11 44.2 0.0 1.7e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFQ91867.1 - 9.9e-05 22.4 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KFQ91867.1 - 0.00026 21.4 0.1 0.00094 19.5 0.1 1.8 1 1 0 1 1 1 1 RNA helicase GTP_EFTU PF00009.27 KFQ91867.1 - 0.00081 19.0 0.4 0.0035 16.9 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFQ91867.1 - 0.0012 18.2 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KFQ91867.1 - 0.0076 15.4 1.7 1 8.5 0.1 2.9 2 1 1 3 3 3 1 G-protein alpha subunit SRPRB PF09439.10 KFQ91867.1 - 0.0092 15.4 0.0 0.015 14.7 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 KFQ91867.1 - 0.013 15.3 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 KFQ91867.1 - 0.013 15.0 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 KFQ91867.1 - 0.021 14.4 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ArgoMid PF16487.5 KFQ91867.1 - 0.03 14.6 0.1 0.054 13.8 0.1 1.4 1 0 0 1 1 1 0 Mid domain of argonaute Septin PF00735.18 KFQ91867.1 - 0.036 13.3 0.0 0.06 12.6 0.0 1.4 1 0 0 1 1 1 0 Septin RsgA_GTPase PF03193.16 KFQ91867.1 - 0.066 13.1 0.1 8.7 6.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 KFQ91867.1 - 0.071 13.1 0.1 0.14 12.1 0.1 1.5 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 KFQ91867.1 - 0.072 13.5 0.0 0.099 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KFQ91867.1 - 0.11 12.7 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain 7tm_2 PF00002.24 KFQ91868.1 - 4.7e-54 183.3 18.5 8.8e-54 182.4 18.5 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Laminin_G_3 PF13385.6 KFQ91868.1 - 4.4e-16 59.4 0.1 7.9e-16 58.6 0.1 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily GPS PF01825.21 KFQ91868.1 - 2.2e-12 47.3 1.4 2.2e-12 47.3 1.4 2.0 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif Dicty_CAR PF05462.11 KFQ91868.1 - 9.4e-08 31.5 15.6 1.6e-07 30.8 15.6 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Pentaxin PF00354.17 KFQ91868.1 - 0.0086 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Pentaxin family DRY_EERY PF09750.9 KFQ91869.1 - 1.4e-33 116.0 2.2 1.4e-33 116.0 2.2 4.7 4 1 2 6 6 6 1 Alternative splicing regulator Surp PF01805.20 KFQ91869.1 - 1.5e-26 92.1 7.6 4.1e-13 49.1 0.9 2.5 2 0 0 2 2 2 2 Surp module Bindin PF02084.15 KFQ91869.1 - 0.07 13.4 0.3 0.07 13.4 0.3 2.2 2 0 0 2 2 2 0 Bindin FANCM-MHF_bd PF16783.5 KFQ91869.1 - 4.2 7.5 8.9 0.12 12.5 1.0 2.5 2 0 0 2 2 2 0 FANCM to MHF binding domain Peptidase_M10 PF00413.24 KFQ91870.1 - 1.8e-49 167.6 0.4 3.5e-49 166.7 0.4 1.5 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 KFQ91870.1 - 1.3e-48 162.7 21.1 1.1e-13 50.9 0.5 5.1 5 0 0 5 5 5 4 Hemopexin PG_binding_1 PF01471.18 KFQ91870.1 - 2.2e-11 43.8 0.1 4.9e-11 42.7 0.1 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Peptidase_M66 PF10462.9 KFQ91870.1 - 0.046 12.7 0.1 0.075 12.0 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Astacin PF01400.24 KFQ91870.1 - 0.049 13.2 1.9 0.74 9.4 1.0 2.3 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Pkinase PF00069.25 KFQ91871.1 - 1.9e-67 227.4 1.8 3.8e-67 226.4 0.1 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ91871.1 - 6.8e-49 166.5 0.0 1.2e-48 165.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 KFQ91871.1 - 1.8e-25 89.8 6.1 4.1e-25 88.6 6.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Kdo PF06293.14 KFQ91871.1 - 9.9e-07 28.3 0.0 2.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFQ91871.1 - 7.1e-05 22.5 0.1 0.00012 21.7 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KFQ91871.1 - 0.00038 19.9 0.0 0.0012 18.2 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFQ91871.1 - 0.0015 17.4 0.1 0.0028 16.5 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFQ91871.1 - 0.015 15.3 0.0 0.081 12.8 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family PseudoU_synth_1 PF01416.20 KFQ91872.1 - 7.3e-13 48.9 0.0 2.6e-11 43.9 0.0 2.5 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF2344 PF10105.9 KFQ91872.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) EP400_N PF15790.5 KFQ91873.1 - 3.3e-278 923.3 40.9 3.3e-278 923.3 40.9 6.6 4 3 1 5 5 5 1 E1A-binding protein p400, N-terminal SNF2_N PF00176.23 KFQ91873.1 - 4.8e-48 163.7 2.0 4.8e-48 163.7 2.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain HSA PF07529.13 KFQ91873.1 - 4.7e-20 71.7 11.1 4.7e-20 71.7 11.1 3.6 3 1 1 4 4 4 1 HSA Helicase_C PF00271.31 KFQ91873.1 - 6.4e-09 36.2 0.1 1.9e-08 34.6 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Myb_DNA-binding PF00249.31 KFQ91873.1 - 5.6e-05 23.2 0.0 0.00021 21.4 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KFQ91873.1 - 0.0023 18.2 0.0 0.0023 18.2 0.0 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFQ91873.1 - 0.0035 17.6 2.2 0.0077 16.5 0.1 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain CBF PF03914.17 KFQ91874.1 - 1.4e-36 126.1 0.7 2.3e-36 125.4 0.7 1.3 1 0 0 1 1 1 1 CBF/Mak21 family Muted PF14942.6 KFQ91874.1 - 0.016 15.6 2.0 1.6 9.0 0.2 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Glycos_transf_2 PF00535.26 KFQ91875.1 - 3e-26 92.2 0.1 6e-26 91.3 0.1 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFQ91875.1 - 1.9e-20 73.4 0.0 3e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 KFQ91875.1 - 1.5e-06 28.3 0.0 1.7e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KFQ91875.1 - 0.0056 16.3 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Auts2 PF15336.6 KFQ91877.1 - 1.2e-109 365.5 11.7 1.2e-109 365.5 11.7 5.7 6 1 0 7 7 7 3 Autism susceptibility gene 2 protein ATG16 PF08614.11 KFQ91879.1 - 0.00054 20.2 26.6 0.00054 20.2 26.6 12.3 2 2 10 12 12 12 4 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 KFQ91879.1 - 0.0073 16.3 12.8 0.0073 16.3 12.8 18.7 6 4 13 19 19 19 4 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 KFQ91879.1 - 0.008 16.2 14.6 0.008 16.2 14.6 12.4 3 1 11 14 14 14 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LEM PF03020.15 KFQ91880.1 - 3.7e-11 42.4 1.1 9.7e-11 41.1 0.0 2.1 2 0 0 2 2 2 1 LEM domain Ank_5 PF13857.6 KFQ91880.1 - 2.9e-09 37.0 0.0 0.0022 18.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFQ91880.1 - 9.2e-09 35.8 0.0 1e-05 26.0 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFQ91880.1 - 8.2e-05 22.7 0.1 0.11 13.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Cauli_VI PF01693.16 KFQ91880.1 - 8.8e-05 22.7 0.1 0.00026 21.2 0.1 1.8 1 0 0 1 1 1 1 Caulimovirus viroplasmin Ank_4 PF13637.6 KFQ91880.1 - 0.00013 22.4 0.1 0.00068 20.1 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KFQ91880.1 - 0.00069 19.9 0.0 0.29 11.7 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat DUF406 PF04175.12 KFQ91880.1 - 0.05 14.1 0.0 0.22 12.0 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF406) His_Phos_1 PF00300.22 KFQ91881.1 - 6.9e-23 81.4 0.4 3.8e-21 75.7 0.4 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DHHC PF01529.20 KFQ91882.1 - 3.3e-36 124.3 10.1 3.4e-35 121.1 11.4 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ran_BP1 PF00638.18 KFQ91883.1 - 4.4e-55 185.2 0.4 5.4e-55 184.9 0.4 1.1 1 0 0 1 1 1 1 RanBP1 domain tRNA_U5-meth_tr PF05958.11 KFQ91884.1 - 4.9e-19 68.5 0.2 2.4e-18 66.2 0.2 2.0 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 KFQ91884.1 - 6.4e-12 45.5 0.0 1.1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFQ91884.1 - 4.5e-10 40.1 0.2 1e-09 38.9 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KFQ91884.1 - 4.2e-07 29.6 0.3 8e-07 28.7 0.3 1.4 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 KFQ91884.1 - 5e-07 29.7 0.0 8.5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KFQ91884.1 - 8.1e-07 28.7 0.0 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 KFQ91884.1 - 5.2e-06 27.0 0.1 2.9e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KFQ91884.1 - 1e-05 25.1 0.1 1.7e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 KFQ91884.1 - 1.3e-05 24.9 0.0 2.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 KFQ91884.1 - 1.7e-05 24.4 0.0 3.9e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase RRM_1 PF00076.22 KFQ91884.1 - 2.9e-05 23.8 0.0 6.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_32 PF13679.6 KFQ91884.1 - 9.9e-05 22.4 0.1 0.00025 21.1 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFQ91884.1 - 0.00015 21.1 0.1 0.00027 20.3 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 KFQ91884.1 - 0.00018 21.5 0.1 0.00037 20.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFQ91884.1 - 0.0018 18.1 0.0 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 KFQ91884.1 - 0.0061 16.3 0.7 0.012 15.3 0.0 1.7 2 0 0 2 2 2 1 DNA methylase CMAS PF02353.20 KFQ91884.1 - 0.0099 15.2 0.1 0.017 14.4 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Met_10 PF02475.16 KFQ91884.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein UPF0020 PF01170.18 KFQ91884.1 - 0.021 14.5 0.6 0.13 11.9 0.6 2.1 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 RrnaAD PF00398.20 KFQ91884.1 - 0.023 13.8 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TPMT PF05724.11 KFQ91884.1 - 0.025 14.3 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MetW PF07021.12 KFQ91884.1 - 0.046 13.3 0.1 0.085 12.4 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DREV PF05219.12 KFQ91884.1 - 0.097 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase dsrm PF00035.26 KFQ91885.1 - 2e-20 73.2 4.0 2.6e-12 47.3 0.0 4.0 3 1 0 3 3 3 2 Double-stranded RNA binding motif TANGO2 PF05742.12 KFQ91886.1 - 4.9e-05 23.5 0.0 4.9e-05 23.5 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Arm PF00514.23 KFQ91887.1 - 2.4e-39 132.2 0.8 1.9e-08 34.1 0.0 7.6 7 0 0 7 7 7 5 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KFQ91887.1 - 1.2e-10 41.6 1.2 0.25 11.9 0.1 5.3 5 0 0 5 5 5 3 HEAT-like repeat HEAT_2 PF13646.6 KFQ91887.1 - 1.7e-10 41.2 0.4 0.00015 22.1 0.0 3.3 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.22 KFQ91887.1 - 2.2e-09 36.7 0.6 0.68 10.3 0.0 5.2 5 0 0 5 5 5 3 HEAT repeat Arm_2 PF04826.13 KFQ91887.1 - 4.1e-06 26.4 0.2 0.021 14.3 0.0 3.7 2 2 1 4 4 4 2 Armadillo-like Atx10homo_assoc PF09759.9 KFQ91887.1 - 0.00016 21.6 0.1 0.0075 16.3 0.0 2.8 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Cnd1 PF12717.7 KFQ91887.1 - 0.0022 18.0 0.2 0.38 10.8 0.2 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 UNC45-central PF11701.8 KFQ91887.1 - 0.12 12.3 0.9 5.7 6.9 0.1 3.1 2 1 0 3 3 3 0 Myosin-binding striated muscle assembly central Methyltransf_3 PF01596.17 KFQ91888.1 - 3.1e-22 78.8 0.0 4.4e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KFQ91888.1 - 2.5e-14 54.2 0.0 3.7e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 KFQ91888.1 - 8.2e-05 22.4 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_31 PF13847.6 KFQ91888.1 - 0.00018 21.3 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFQ91888.1 - 0.0027 17.5 0.0 0.0041 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14 PF08704.10 KFQ91888.1 - 0.049 13.3 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Cons_hypoth95 PF03602.15 KFQ91888.1 - 0.074 12.7 0.0 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Met_10 PF02475.16 KFQ91888.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Pyr_redox_2 PF07992.14 KFQ91889.1 - 1.6e-49 168.7 0.0 2.6e-49 168.1 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFQ91889.1 - 5.7e-31 107.0 0.0 1e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFQ91889.1 - 3.1e-12 46.9 0.2 9.4e-08 32.5 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFQ91889.1 - 2.1e-07 30.4 4.6 9e-07 28.3 2.4 2.5 2 1 1 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.6 KFQ91889.1 - 2.6e-06 26.9 3.3 0.029 13.6 0.4 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFQ91889.1 - 8.7e-06 24.7 0.4 0.00048 18.9 0.2 2.4 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KFQ91889.1 - 8.2e-05 21.9 1.6 0.00036 19.8 1.6 1.9 1 1 0 1 1 1 1 Glucose inhibited division protein A K_oxygenase PF13434.6 KFQ91889.1 - 9.3e-05 21.7 0.3 0.023 13.8 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KFQ91889.1 - 0.00026 20.3 0.0 0.00044 19.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KFQ91889.1 - 0.0004 19.9 0.3 0.00099 18.6 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFQ91889.1 - 0.0024 18.1 0.3 0.0067 16.6 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFQ91889.1 - 0.0026 17.4 4.0 0.0047 16.6 1.0 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KFQ91889.1 - 0.0056 16.0 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF1775 PF07987.11 KFQ91889.1 - 0.088 13.1 0.7 8.1 6.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unkown function (DUF1775) Lycopene_cycl PF05834.12 KFQ91889.1 - 0.57 9.2 1.7 0.44 9.5 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein WD40 PF00400.32 KFQ91890.1 - 5.3e-23 80.9 6.8 0.00014 22.6 0.3 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ91890.1 - 5.6e-09 36.2 0.1 0.062 13.6 0.1 4.0 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Septin PF00735.18 KFQ91891.1 - 2.5e-131 437.1 0.5 2.8e-131 436.9 0.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFQ91891.1 - 1.7e-08 34.5 0.0 3.5e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFQ91891.1 - 1.3e-07 31.7 0.2 1.7e-05 24.8 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KFQ91891.1 - 1.2e-05 25.0 0.2 0.029 13.9 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KFQ91891.1 - 0.00094 18.6 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KFQ91891.1 - 0.003 17.7 1.7 0.38 10.8 0.0 2.6 1 1 1 2 2 2 1 Dynamin family Ras PF00071.22 KFQ91891.1 - 0.008 15.8 0.1 0.018 14.6 0.1 1.6 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ91891.1 - 0.014 15.7 0.1 0.026 14.7 0.1 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KFQ91891.1 - 0.015 15.7 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KFQ91891.1 - 0.035 13.8 0.1 0.087 12.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KFQ91891.1 - 0.039 14.5 0.2 0.06 13.9 0.2 1.6 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KFQ91891.1 - 0.05 13.9 0.0 0.13 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFQ91891.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 KFQ91891.1 - 0.2 12.2 2.8 0.89 10.0 2.8 1.9 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 KFQ91892.1 - 4.4e-124 413.3 0.0 7.6e-122 406.0 0.0 2.1 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFQ91892.1 - 3.2e-08 33.7 0.0 1e-07 32.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFQ91892.1 - 9.1e-06 25.3 0.0 0.0028 17.2 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KFQ91892.1 - 5e-05 22.7 0.9 0.00013 21.4 0.0 1.9 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 KFQ91892.1 - 6.1e-05 23.0 1.3 0.0011 18.9 0.3 2.6 2 1 0 2 2 2 1 RsgA GTPase Ras PF00071.22 KFQ91892.1 - 8.9e-05 22.1 0.0 0.00025 20.7 0.0 1.8 1 1 0 1 1 1 1 Ras family Dynamin_N PF00350.23 KFQ91892.1 - 0.00033 20.7 1.8 0.13 12.3 0.0 2.9 2 1 1 3 3 3 2 Dynamin family Roc PF08477.13 KFQ91892.1 - 0.0036 17.5 0.0 0.0066 16.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KFQ91892.1 - 0.0043 17.3 1.1 0.017 15.4 0.0 2.5 3 2 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KFQ91892.1 - 0.0064 16.9 0.0 0.015 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KFQ91892.1 - 0.0093 15.5 0.1 0.024 14.2 0.0 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region Gtr1_RagA PF04670.12 KFQ91892.1 - 0.011 15.1 0.1 0.059 12.7 0.0 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 KFQ91892.1 - 0.02 14.6 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KFQ91892.1 - 0.024 15.1 2.0 0.031 14.8 0.2 2.0 2 1 0 2 2 2 0 ABC transporter G-alpha PF00503.20 KFQ91892.1 - 0.066 12.4 0.0 4.7 6.3 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit NACHT PF05729.12 KFQ91892.1 - 0.14 12.0 0.1 0.69 9.8 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Sec2p PF06428.11 KFQ91892.1 - 0.22 11.5 4.4 0.32 11.0 3.5 1.8 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p AAA_28 PF13521.6 KFQ91892.1 - 0.63 10.3 2.8 21 5.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain CDC45 PF02724.14 KFQ91893.1 - 5.7e-159 530.4 19.5 8e-78 262.3 11.5 3.0 1 1 2 3 3 3 3 CDC45-like protein DUF3848 PF12959.7 KFQ91893.1 - 0.026 14.6 1.0 0.28 11.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) UBA2_C PF16195.5 KFQ91893.1 - 0.35 11.6 7.1 6.4 7.5 6.1 2.4 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus UFD1 PF03152.14 KFQ91894.1 - 6.4e-80 266.7 0.0 7.8e-80 266.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 KFQ91894.1 - 0.14 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 MRP-L28 PF09812.9 KFQ91895.1 - 1.7e-48 164.8 8.3 2e-48 164.6 8.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 DUF4207 PF13904.6 KFQ91895.1 - 0.0005 19.8 9.6 0.00067 19.4 9.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) FliD_N PF02465.18 KFQ91895.1 - 0.21 12.3 2.4 6.2 7.6 0.1 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Hira PF07569.11 KFQ91896.1 - 8.6e-58 195.7 0.2 2.2e-57 194.3 0.2 1.8 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 KFQ91896.1 - 2.4e-28 97.8 31.7 2.5e-08 34.4 4.0 8.6 8 1 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ91896.1 - 7.4e-11 42.2 4.8 0.013 15.8 0.0 6.0 4 1 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 KFQ91896.1 - 4.5e-08 32.8 0.0 1.2e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 HIRA B motif TFIIIC_delta PF12657.7 KFQ91896.1 - 0.024 14.6 2.4 0.6 10.0 0.1 3.5 3 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term WD40_like PF17005.5 KFQ91896.1 - 0.073 12.4 0.0 0.55 9.5 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain Pro_isomerase PF00160.21 KFQ91897.1 - 6.4e-52 176.0 0.1 1.3e-51 175.0 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 KFQ91897.1 - 0.0018 17.7 0.1 0.0018 17.7 0.1 2.2 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.15 KFQ91897.1 - 0.004 17.3 0.0 0.019 15.1 0.0 2.2 2 0 0 2 2 2 1 U-box domain Yippee-Mis18 PF03226.14 KFQ91898.1 - 1.1e-12 48.1 0.1 1.3e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 KFQ91898.1 - 0.016 15.4 0.2 0.028 14.6 0.2 1.4 1 1 0 1 1 1 0 C-terminal domain of RIG-I Evr1_Alr PF04777.13 KFQ91898.1 - 0.057 13.9 2.6 0.43 11.1 2.6 2.0 1 1 0 1 1 1 0 Erv1 / Alr family zf-CHY PF05495.12 KFQ91898.1 - 0.076 13.5 6.8 0.27 11.7 6.8 1.9 1 1 0 1 1 1 0 CHY zinc finger PP2C PF00481.21 KFQ91899.1 - 1.7e-64 218.0 0.0 2e-64 217.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFQ91899.1 - 0.0042 16.7 0.2 0.025 14.2 0.2 2.4 1 1 0 1 1 1 1 Protein phosphatase 2C HHH_5 PF14520.6 KFQ91899.1 - 0.062 13.9 0.1 0.15 12.7 0.0 1.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain Acetyltransf_1 PF00583.25 KFQ91899.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Topoisom_bac PF01131.20 KFQ91900.1 - 4.3e-119 398.2 0.0 5.2e-119 397.9 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 KFQ91900.1 - 7.7e-14 51.8 0.0 1.7e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Toprim domain DUF2204 PF09970.9 KFQ91900.1 - 0.14 11.8 0.1 0.91 9.1 0.0 2.0 2 0 0 2 2 2 0 Nucleotidyl transferase of unknown function (DUF2204) MIR PF02815.19 KFQ91901.1 - 9.6e-13 48.4 0.0 1.1e-09 38.4 0.0 2.0 1 1 1 2 2 2 2 MIR domain YdjC PF04794.12 KFQ91902.1 - 7.7e-34 117.7 0.0 9e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 YdjC-like protein UQ_con PF00179.26 KFQ91903.1 - 5.3e-44 149.3 0.4 6e-44 149.1 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFQ91903.1 - 3.7e-05 24.0 0.1 5.1e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KFQ91903.1 - 3.9e-05 23.4 0.0 4.9e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KFQ91903.1 - 4.2e-05 23.4 0.1 7.4e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 UEV domain BTB PF00651.31 KFQ91904.1 - 9.8e-27 93.4 0.2 1.5e-26 92.8 0.2 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 KFQ91904.1 - 1.6e-26 91.2 24.4 7.4e-06 26.1 1.3 5.8 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ91904.1 - 2.5e-23 80.8 22.7 0.00032 21.3 0.5 5.9 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFQ91904.1 - 2.2e-19 68.9 30.5 5.8e-08 32.8 0.2 7.4 6 1 0 6 6 6 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFQ91904.1 - 7e-16 58.1 3.4 0.00027 21.1 0.3 5.9 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFQ91904.1 - 2.2e-11 43.8 13.3 0.0035 17.7 0.4 5.8 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFQ91904.1 - 3.6e-10 39.6 21.5 0.018 15.0 0.3 5.9 5 1 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KFQ91904.1 - 1.2e-05 26.0 5.6 0.004 17.8 0.3 4.2 1 1 2 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 KFQ91904.1 - 8.6e-05 22.2 16.6 0.23 11.2 0.4 4.7 5 0 0 5 5 4 3 zinc-finger C2H2-type zf-Di19 PF05605.12 KFQ91904.1 - 0.00022 21.5 10.9 0.051 13.9 0.6 3.6 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KFQ91904.1 - 0.00061 20.1 12.5 7.4 7.0 0.2 5.1 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_8 PF15909.5 KFQ91904.1 - 0.0013 19.0 10.0 7.6 6.9 0.8 4.5 1 1 3 4 4 4 0 C2H2-type zinc ribbon zf_C2H2_ZHX PF18387.1 KFQ91904.1 - 0.0018 17.9 4.4 2 8.1 0.0 3.7 3 0 0 3 3 3 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-UBP PF02148.19 KFQ91904.1 - 0.0068 16.7 6.0 2.5 8.5 0.1 3.7 2 1 1 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein zf-C2HE PF16278.5 KFQ91904.1 - 0.0091 16.4 15.9 0.68 10.4 0.3 5.5 1 1 4 5 5 5 1 C2HE / C2H2 / C2HC zinc-binding finger zf_UBZ PF18439.1 KFQ91904.1 - 0.034 13.8 10.6 3.2 7.4 0.1 5.2 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-AN1 PF01428.16 KFQ91904.1 - 0.057 13.6 10.3 29 4.9 0.2 4.6 4 0 0 4 4 4 0 AN1-like Zinc finger zf-MYST PF17772.1 KFQ91904.1 - 0.072 12.7 0.1 12 5.6 0.0 3.5 3 0 0 3 3 3 0 MYST family zinc finger domain GAGA PF09237.11 KFQ91904.1 - 0.14 11.9 3.9 1.6 8.6 0.2 3.0 2 1 1 3 3 3 0 GAGA factor zf-H2C2_5 PF13909.6 KFQ91904.1 - 0.26 11.1 22.1 4.6 7.1 0.1 5.7 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-BED PF02892.15 KFQ91904.1 - 0.28 11.2 16.4 2 8.5 3.7 4.9 4 1 1 5 5 4 0 BED zinc finger Zn-C2H2_12 PF18112.1 KFQ91904.1 - 0.61 10.6 3.4 64 4.1 0.0 4.1 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zinc_ribbon_15 PF17032.5 KFQ91904.1 - 0.89 10.3 8.5 18 6.1 3.0 3.5 1 1 2 3 3 3 0 zinc-ribbon family C1_1 PF00130.22 KFQ91904.1 - 0.97 9.4 7.5 1.1 9.1 1.4 3.4 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.21 KFQ91904.1 - 1.1 9.5 9.1 2.6 8.2 1.1 2.9 1 1 0 2 2 2 0 FYVE zinc finger zf-HYPF PF07503.12 KFQ91904.1 - 2.8 7.8 7.0 17 5.3 0.4 3.4 3 1 0 3 3 3 0 HypF finger LIM PF00412.22 KFQ91904.1 - 6.2 7.1 13.9 0.24 11.7 0.5 3.8 3 1 2 5 5 3 0 LIM domain zf-RING_5 PF14634.6 KFQ91904.1 - 7.3 6.6 8.4 1.1e+02 2.9 0.1 3.7 2 1 0 2 2 2 0 zinc-RING finger domain zf-LYAR PF08790.11 KFQ91904.1 - 8.6 6.4 11.6 2.2 8.3 0.1 4.5 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger Zn-ribbon_8 PF09723.10 KFQ91904.1 - 9.4 6.4 14.6 4.1 7.6 4.4 4.1 2 1 3 5 5 5 0 Zinc ribbon domain Cadherin_2 PF08266.12 KFQ91905.1 - 2.9e-24 84.7 0.1 3.4e-23 81.3 0.0 2.1 2 0 0 2 2 2 1 Cadherin-like Cadherin PF00028.17 KFQ91905.1 - 1.2e-16 61.0 0.0 1.9e-10 41.1 0.0 2.3 2 0 0 2 2 2 2 Cadherin domain Cadherin PF00028.17 KFQ91906.1 - 4.2e-15 55.9 0.0 5.7e-14 52.3 0.0 2.0 2 0 0 2 2 2 1 Cadherin domain Cadherin_3 PF16184.5 KFQ91906.1 - 0.044 13.8 0.1 1 9.4 0.1 2.2 2 0 0 2 2 2 0 Cadherin-like Cadherin-like PF12733.7 KFQ91906.1 - 0.083 13.4 0.1 0.14 12.7 0.1 1.4 1 1 0 1 1 1 0 Cadherin-like beta sandwich domain Nrap_D4 PF17405.2 KFQ91908.1 - 7.9e-53 179.0 0.0 1.5e-52 178.1 0.0 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap PF03813.14 KFQ91908.1 - 2.7e-47 160.6 0.1 5.2e-47 159.7 0.1 1.5 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D2 PF17403.2 KFQ91908.1 - 1.1e-43 148.7 0.7 8.6e-42 142.5 0.3 2.3 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D3 PF17404.2 KFQ91908.1 - 6.5e-40 136.8 0.0 1.1e-39 136.0 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 KFQ91908.1 - 1.7e-30 106.0 0.0 5e-30 104.5 0.0 1.9 2 0 0 2 2 2 1 Nrap protein domain 6 Nrap_D5 PF17406.2 KFQ91908.1 - 4.5e-30 104.6 0.3 7.4e-28 97.4 0.1 2.5 2 0 0 2 2 2 2 Nrap protein PAP/OAS1-like domain 5 Pkinase PF00069.25 KFQ91909.1 - 9.8e-73 244.8 0.4 7.9e-70 235.2 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain cNMP_binding PF00027.29 KFQ91909.1 - 4.7e-38 129.1 0.1 1.1e-19 70.3 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 KFQ91909.1 - 4.5e-34 117.9 0.0 5.7e-33 114.3 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ91909.1 - 0.00061 19.2 0.0 0.001 18.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like ATG16 PF08614.11 KFQ91909.1 - 0.0031 17.8 4.1 0.0071 16.6 4.1 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Nup54 PF13874.6 KFQ91909.1 - 0.016 15.4 2.6 0.04 14.0 2.6 1.6 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Antigen_Bd37 PF11641.8 KFQ91909.1 - 0.026 14.1 1.6 0.038 13.5 0.1 1.9 2 0 0 2 2 2 0 Glycosylphosphatidylinositol-anchored merozoite surface protein Corona_S2 PF01601.16 KFQ91909.1 - 0.047 12.2 0.7 0.079 11.4 0.7 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein APH PF01636.23 KFQ91909.1 - 0.066 13.1 0.3 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family ID PF18543.1 KFQ91909.1 - 0.086 12.9 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Intracellular delivery domain PKcGMP_CC PF16808.5 KFQ91909.1 - 0.15 11.9 10.0 2.1 8.3 0.3 2.7 1 1 1 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3552 PF12072.8 KFQ91909.1 - 0.25 10.7 5.8 0.53 9.7 5.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4200 PF13863.6 KFQ91909.1 - 5.1 7.5 11.6 5.9 7.3 2.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) RasGEF PF00617.19 KFQ91910.1 - 3e-52 177.4 1.2 3.7e-52 177.1 0.2 1.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KFQ91910.1 - 2.1e-16 60.1 1.3 5.6e-16 58.7 0.1 2.2 2 1 0 2 2 2 1 RasGEF N-terminal motif RNase_H2-Ydr279 PF09468.10 KFQ91910.1 - 0.062 13.5 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain DUF846 PF05832.12 KFQ91911.1 - 8.8e-55 184.6 8.7 1e-54 184.3 8.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TMEM192 PF14802.6 KFQ91911.1 - 0.15 11.1 1.9 0.3 10.2 1.9 1.4 1 0 0 1 1 1 0 TMEM192 family Tektin PF03148.14 KFQ91912.1 - 3.3e-153 510.0 32.8 3.8e-153 509.8 32.8 1.0 1 0 0 1 1 1 1 Tektin family Dna2 PF08696.11 KFQ91912.1 - 0.061 13.1 0.4 0.061 13.1 0.4 2.3 2 1 0 2 2 2 0 DNA replication factor Dna2 DUF3742 PF12553.8 KFQ91912.1 - 0.19 11.8 0.6 2.2 8.4 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3742) Baculo_PEP_C PF04513.12 KFQ91912.1 - 0.3 11.1 7.1 0.71 9.9 1.7 3.1 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus JIP_LZII PF16471.5 KFQ91912.1 - 6.2 7.1 13.7 5.7 7.2 0.5 4.0 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II PMP22_Claudin PF00822.20 KFQ91913.1 - 1.2e-31 109.8 9.0 1.3e-31 109.7 9.0 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFQ91913.1 - 1.9e-08 34.3 11.5 2.1e-08 34.1 11.5 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF2723 PF11028.8 KFQ91913.1 - 0.0068 16.3 5.5 0.0082 16.1 5.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2723) SUR7 PF06687.12 KFQ91913.1 - 0.022 14.4 10.9 0.026 14.2 10.9 1.1 1 0 0 1 1 1 0 SUR7/PalI family L_HMGIC_fpl PF10242.9 KFQ91913.1 - 0.045 14.0 8.0 0.068 13.4 8.0 1.5 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein Amastin PF07344.11 KFQ91913.1 - 0.048 13.5 7.0 0.058 13.2 7.0 1.1 1 0 0 1 1 1 0 Amastin surface glycoprotein DUF1980 PF09323.10 KFQ91913.1 - 0.052 13.5 0.2 0.083 12.8 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) 7TMR-DISM_7TM PF07695.11 KFQ91913.1 - 0.14 12.0 12.8 0.16 11.8 11.5 1.5 1 1 0 1 1 1 0 7TM diverse intracellular signalling Clc-like PF07062.12 KFQ91913.1 - 0.53 9.7 11.1 0.99 8.8 11.1 1.5 1 1 0 1 1 1 0 Clc-like TspO_MBR PF03073.15 KFQ91913.1 - 0.67 10.0 8.5 0.92 9.6 8.5 1.2 1 0 0 1 1 1 0 TspO/MBR family DUF2207 PF09972.9 KFQ91913.1 - 1.9 7.2 6.2 2.3 6.9 6.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4064 PF13273.6 KFQ91913.1 - 4.1 7.7 11.8 1.6 9.1 5.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF2721 PF11026.8 KFQ91913.1 - 6.5 6.7 11.6 0.18 11.7 5.6 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) MARVEL PF01284.23 KFQ91913.1 - 6.7 6.7 13.0 21 5.1 12.5 1.8 1 1 0 1 1 1 0 Membrane-associating domain Gram_pos_anchor PF00746.21 KFQ91913.1 - 7.7 6.6 5.1 68 3.5 0.1 3.0 3 0 0 3 3 3 0 LPXTG cell wall anchor motif Sulfotransfer_1 PF00685.27 KFQ91914.1 - 9.3e-32 110.6 0.0 1.1e-31 110.3 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFQ91914.1 - 1.3e-10 42.0 0.0 1.9e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFQ91914.1 - 0.0081 16.1 0.0 0.071 13.0 0.0 2.0 2 0 0 2 2 2 1 Sulfotransferase family UbiA PF01040.18 KFQ91915.1 - 9.2e-55 185.7 14.1 1.3e-54 185.1 14.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF515 PF04415.12 KFQ91915.1 - 0.058 11.8 0.2 0.082 11.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Y_phosphatase PF00102.27 KFQ91917.1 - 1.4e-160 532.0 0.6 3.5e-82 275.5 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 KFQ91917.1 - 1e-117 384.7 28.7 2.9e-16 59.6 0.2 9.6 10 0 0 10 10 9 8 Fibronectin type III domain I-set PF07679.16 KFQ91917.1 - 1.1e-39 134.3 0.0 8.7e-15 54.6 0.0 4.5 5 0 0 5 5 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ91917.1 - 1.5e-39 134.4 1.9 1.1e-11 45.1 0.0 5.8 6 0 0 6 6 5 3 Immunoglobulin domain Ig_2 PF13895.6 KFQ91917.1 - 1.2e-21 76.8 0.2 1.5e-07 31.6 0.0 4.6 4 0 0 4 4 4 3 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFQ91917.1 - 4.5e-19 68.8 17.7 0.01 16.4 0.2 9.4 8 2 0 8 8 8 4 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.5 KFQ91917.1 - 4.8e-16 58.7 0.4 0.036 14.2 0.0 7.8 7 1 0 7 7 7 3 Fibronectin type III domain ig PF00047.25 KFQ91917.1 - 4.4e-14 52.4 0.0 0.0064 16.6 0.0 4.2 4 0 0 4 4 3 3 Immunoglobulin domain Interfer-bind PF09294.10 KFQ91917.1 - 5.3e-11 42.7 0.1 1.2 9.5 0.0 7.2 7 0 0 7 7 6 2 Interferon-alpha/beta receptor, fibronectin type III DSPc PF00782.20 KFQ91917.1 - 4.9e-08 32.9 0.0 0.0085 15.9 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain V-set PF07686.17 KFQ91917.1 - 7.7e-08 32.5 0.0 0.02 15.0 0.0 5.1 3 1 0 3 3 3 2 Immunoglobulin V-set domain Y_phosphatase3 PF13350.6 KFQ91917.1 - 8.9e-07 29.1 0.0 0.052 13.5 0.0 2.3 2 0 0 2 2 2 2 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFQ91917.1 - 1.2e-05 25.5 0.0 0.0057 16.8 0.0 2.7 2 0 0 2 2 2 1 Inositol hexakisphosphate fn3_4 PF16794.5 KFQ91917.1 - 1.2e-05 25.2 3.0 0.091 12.7 0.0 7.2 9 1 0 9 9 8 1 Fibronectin-III type domain DUF2369 PF10179.9 KFQ91917.1 - 1.2e-05 25.6 0.4 14 6.2 0.0 6.6 8 0 0 8 8 7 0 Uncharacterised conserved protein (DUF2369) Ig_C17orf99 PF17736.1 KFQ91917.1 - 3.8e-05 23.6 0.0 1.4 9.0 0.0 4.9 5 0 0 5 5 5 1 C17orf99 Ig domain C2-set_2 PF08205.12 KFQ91917.1 - 5.8e-05 23.1 0.1 2.9 8.0 0.0 3.8 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFQ91917.1 - 0.00034 21.0 0.0 0.2 12.1 0.0 3.9 4 0 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Glyco_hydro_36C PF16874.5 KFQ91917.1 - 0.013 16.0 0.0 48 4.6 0.0 4.2 4 0 0 4 4 3 0 Glycosyl hydrolase family 36 C-terminal domain Reeler PF02014.16 KFQ91917.1 - 0.094 13.5 0.2 26 5.6 0.0 4.6 5 0 0 5 5 4 0 Reeler domain Glyco_hydro_46 PF01374.18 KFQ91917.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 46 Big_5 PF13205.6 KFQ91917.1 - 0.18 12.5 4.3 68 4.2 0.2 4.6 3 1 1 4 4 4 0 Bacterial Ig-like domain GDC-P PF02347.16 KFQ91918.1 - 1.7e-195 649.9 0.0 2.6e-183 609.7 0.0 3.0 3 0 0 3 3 3 3 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KFQ91918.1 - 1.4e-09 37.7 0.1 4.2e-09 36.1 0.0 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KFQ91918.1 - 1.7e-05 24.0 0.2 7.6e-05 21.8 0.1 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KFQ91918.1 - 0.0048 16.1 0.0 0.018 14.2 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II Pyridoxal_deC PF00282.19 KFQ91918.1 - 0.0057 15.4 0.2 0.3 9.8 0.1 2.2 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain DUF5090 PF17009.5 KFQ91920.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) DUF3886 PF13025.6 KFQ91920.1 - 3.3 8.0 21.7 0.19 11.9 6.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) MLANA PF14991.6 KFQ91922.1 - 6.9e-36 123.1 0.1 7.8e-36 122.9 0.1 1.0 1 0 0 1 1 1 1 Protein melan-A WBP-1 PF11669.8 KFQ91922.1 - 0.21 12.3 0.6 0.44 11.2 0.6 1.5 1 1 0 1 1 1 0 WW domain-binding protein 1 SKG6 PF08693.10 KFQ91922.1 - 0.26 10.7 1.3 0.4 10.1 1.3 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MFS_1 PF07690.16 KFQ91923.1 - 6.9e-36 123.9 37.9 4.6e-25 88.3 23.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2721 PF11026.8 KFQ91923.1 - 0.27 11.1 0.0 0.27 11.1 0.0 3.8 2 2 2 4 4 4 0 Protein of unknown function (DUF2721) SLATT_5 PF18160.1 KFQ91923.1 - 5.3 6.3 8.7 1 8.7 1.0 2.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Peptidase_M28 PF04389.17 KFQ91924.1 - 2.4e-47 161.2 0.0 3.4e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KFQ91924.1 - 0.00011 22.0 0.0 0.00041 20.1 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 SGL PF08450.12 KFQ91924.1 - 0.0094 15.6 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Peptidase_M42 PF05343.14 KFQ91924.1 - 0.19 10.7 0.0 0.33 9.9 0.0 1.3 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase Ig_3 PF13927.6 KFQ91925.1 - 1.6e-11 44.6 0.1 0.00016 22.2 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFQ91925.1 - 9.5e-10 38.5 0.2 0.0013 18.8 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFQ91925.1 - 4.3e-07 30.1 0.0 1.1e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFQ91925.1 - 5.9e-07 29.5 0.1 0.034 14.2 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFQ91925.1 - 2.7e-05 24.4 0.3 0.19 12.1 0.0 3.1 2 2 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.15 KFQ91925.1 - 0.00016 21.9 0.3 0.00048 20.5 0.1 1.9 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFQ91925.1 - 0.00036 20.0 0.0 0.0027 17.2 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.12 KFQ91925.1 - 0.005 16.9 0.1 0.017 15.2 0.0 1.8 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 KFQ91926.1 - 8.1e-13 48.8 0.1 1.6e-05 25.4 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFQ91926.1 - 1.5e-10 40.9 0.1 0.00017 21.6 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 KFQ91926.1 - 3.2e-10 40.1 0.1 1.2e-09 38.3 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KFQ91926.1 - 7e-07 29.5 0.1 0.042 14.2 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFQ91926.1 - 1.9e-06 28.0 1.8 0.011 15.8 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFQ91926.1 - 5.8e-05 23.1 0.1 0.00017 21.6 0.1 1.7 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFQ91926.1 - 0.014 14.9 0.0 0.033 13.8 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain C1-set PF07654.15 KFQ91926.1 - 0.042 14.2 0.9 0.17 12.3 0.3 2.1 2 0 0 2 2 2 0 Immunoglobulin C1-set domain Ig_Tie2_1 PF10430.9 KFQ91926.1 - 0.055 13.9 0.4 0.12 12.8 0.4 1.5 1 0 0 1 1 1 0 Tie-2 Ig-like domain 1 Receptor_2B4 PF11465.8 KFQ91926.1 - 0.063 13.5 0.8 0.3 11.3 0.1 2.1 1 1 0 2 2 2 0 Natural killer cell receptor 2B4 DUF2368 PF10166.9 KFQ91927.1 - 9.9e-48 161.2 0.0 1.1e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2368) Insulin PF00049.18 KFQ91928.1 - 0.028 15.4 0.3 0.041 14.9 0.3 1.4 1 1 0 1 1 1 0 Insulin/IGF/Relaxin family Pkinase_Tyr PF07714.17 KFQ91929.1 - 1.7e-144 479.8 0.0 6e-84 281.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFQ91929.1 - 1.9e-72 243.8 0.0 5.6e-49 166.9 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain FERM_F2 PF18377.1 KFQ91929.1 - 8.4e-44 148.7 0.1 2.1e-43 147.4 0.1 1.8 1 0 0 1 1 1 1 FERM F2 acyl-CoA binding protein-like domain FERM_F1 PF18379.1 KFQ91929.1 - 5.6e-40 135.3 0.5 5.6e-40 135.3 0.5 2.1 2 0 0 2 2 2 1 FERM F1 ubiquitin-like domain Jak1_Phl PF17887.1 KFQ91929.1 - 5.4e-19 68.6 0.6 1.8e-18 66.9 0.2 2.0 1 1 1 2 2 2 1 Jak1 pleckstrin homology-like domain Kdo PF06293.14 KFQ91929.1 - 4.3e-06 26.2 0.6 0.021 14.2 0.2 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family FERM_M PF00373.18 KFQ91929.1 - 0.00052 20.4 0.1 0.0013 19.1 0.1 1.7 1 0 0 1 1 1 1 FERM central domain RIO1 PF01163.22 KFQ91929.1 - 0.0058 16.2 1.9 0.58 9.7 0.1 2.5 2 0 0 2 2 2 2 RIO1 family APH PF01636.23 KFQ91929.1 - 0.038 13.9 0.0 2.1 8.2 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family RTC PF01137.21 KFQ91930.1 - 1.8e-43 148.3 0.0 2e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KFQ91930.1 - 3.2e-36 124.0 0.0 5.1e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Sad1_UNC PF07738.13 KFQ91931.1 - 2.8e-34 118.0 0.0 3.1e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Sad1_UNC PF07738.13 KFQ91932.1 - 2.4e-32 111.7 0.0 2.6e-32 111.6 0.0 1.0 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal SDF PF00375.18 KFQ91933.1 - 1.3e-131 439.2 28.1 1.6e-131 439.0 28.1 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family MTABC_N PF16185.5 KFQ91933.1 - 0.23 10.9 5.6 0.77 9.2 5.6 1.9 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region DUF5083 PF16890.5 KFQ91933.1 - 6.9 6.4 7.1 0.44 10.3 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5083) Ras PF00071.22 KFQ91935.1 - 1.4e-45 154.8 0.0 1.6e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ91935.1 - 2.5e-21 76.1 0.0 3.4e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ91935.1 - 5.5e-11 42.2 0.0 6.9e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Myosin_N PF02736.19 KFQ91937.1 - 1.2e-12 47.5 0.1 1.7e-12 46.9 0.1 1.2 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain HOOK PF05622.12 KFQ91938.1 - 1.6e-27 96.0 10.4 1.7e-27 95.9 10.4 1.0 1 0 0 1 1 1 1 HOOK protein KASH_CCD PF14662.6 KFQ91938.1 - 6.3e-05 22.9 9.3 0.00018 21.4 9.3 1.7 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 KFQ91938.1 - 0.012 15.7 8.9 0.032 14.3 1.7 2.4 2 1 1 3 3 3 0 bZIP transcription factor DUF4795 PF16043.5 KFQ91938.1 - 0.036 13.7 3.9 0.046 13.3 3.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Spc7 PF08317.11 KFQ91938.1 - 0.058 12.3 9.5 0.078 11.8 9.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TolA_bind_tri PF16331.5 KFQ91938.1 - 0.08 13.0 11.9 0.79 9.8 0.8 2.6 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF3450 PF11932.8 KFQ91938.1 - 0.33 10.2 8.2 0.46 9.7 8.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) UPF0449 PF15136.6 KFQ91938.1 - 0.4 11.2 4.7 0.77 10.3 4.5 1.6 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 JIP_LZII PF16471.5 KFQ91938.1 - 0.55 10.4 8.9 0.56 10.4 3.7 2.4 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II UPF0242 PF06785.11 KFQ91938.1 - 0.64 10.1 9.8 0.77 9.8 9.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Synaptobrevin PF00957.21 KFQ91938.1 - 1 9.2 4.0 1.1 9.1 0.5 2.2 1 1 1 2 2 2 0 Synaptobrevin YabA PF06156.13 KFQ91938.1 - 1.9 9.2 8.7 5.8 7.6 3.0 2.1 1 1 1 2 2 2 0 Initiation control protein YabA Spc24 PF08286.11 KFQ91938.1 - 2.6 8.3 8.3 0.51 10.6 4.1 1.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 CTP_transf_1 PF01148.20 KFQ91939.1 - 4e-85 285.8 20.4 5e-85 285.5 20.4 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Beach PF02138.18 KFQ91940.1 - 1.8e-126 421.1 0.1 3e-126 420.4 0.1 1.3 1 0 0 1 1 1 1 Beige/BEACH domain FYVE PF01363.21 KFQ91940.1 - 5.4e-18 64.9 12.4 1.3e-17 63.7 12.4 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH_BEACH PF14844.6 KFQ91940.1 - 1e-12 48.0 0.0 2.9e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 KFQ91940.1 - 9.7e-07 29.4 9.3 0.0038 18.0 0.2 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF4704 PF15787.5 KFQ91940.1 - 2.1e-06 27.2 3.9 3.7e-06 26.4 0.8 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 KFQ91940.1 - 0.0015 18.7 0.0 0.005 17.0 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4800 PF16057.5 KFQ91940.1 - 0.0056 16.0 1.4 0.013 14.8 1.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) E3_UbLigase_R4 PF13764.6 KFQ91940.1 - 0.053 11.7 0.1 0.12 10.5 0.1 1.5 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 WAPL PF07814.13 KFQ91940.1 - 7.1 5.3 9.2 0.26 10.0 0.1 3.0 4 1 0 4 4 4 0 Wings apart-like protein regulation of heterochromatin PP2C PF00481.21 KFQ91941.1 - 3e-55 187.6 0.2 4e-55 187.2 0.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFQ91941.1 - 1.1e-13 51.4 0.0 3e-13 49.9 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KFQ91941.1 - 0.064 13.2 0.2 4.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Mab-21 PF03281.14 KFQ91942.1 - 5.3e-100 334.5 0.0 6.4e-100 334.2 0.0 1.1 1 0 0 1 1 1 1 Mab-21 protein Lactamase_B_6 PF16661.5 KFQ91944.1 - 0.094 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Ribosomal_L7Ae PF01248.26 KFQ91945.1 - 1.4e-08 34.3 0.0 2e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family L_HMGIC_fpl PF10242.9 KFQ91946.1 - 3.3e-36 125.2 1.9 3.8e-36 125.0 1.9 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein DUF4245 PF14030.6 KFQ91946.1 - 3.4 7.7 4.3 2.6 8.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4245) Abhydrolase_1 PF00561.20 KFQ91947.1 - 0.0026 17.4 0.1 0.0043 16.7 0.1 1.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFQ91947.1 - 0.01 15.1 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFQ91947.1 - 0.02 15.5 0.0 0.021 15.4 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Gag_p30 PF02093.16 KFQ91948.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Gag P30 core shell protein HU-DNA_bdg PF14848.6 KFQ91949.1 - 0.17 11.9 6.3 1.2 9.2 0.3 2.8 3 0 0 3 3 3 0 DNA-binding domain DUF3447 PF11929.8 KFQ91949.1 - 0.28 11.1 2.6 0.91 9.5 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3447) zf-C2H2 PF00096.26 KFQ91950.1 - 4.6e-16 58.3 4.7 2e-08 34.3 0.2 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ91950.1 - 3.6e-12 46.0 5.2 3.8e-06 27.3 0.6 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFQ91950.1 - 9.9e-12 44.7 12.2 8.2e-07 29.2 0.8 3.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFQ91950.1 - 5.1e-10 39.4 1.7 0.00017 21.8 0.2 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFQ91950.1 - 8.3e-05 22.5 10.3 0.036 14.1 0.2 2.8 2 1 0 2 2 2 2 C2H2-type zinc finger zf-LYAR PF08790.11 KFQ91950.1 - 0.00017 21.4 2.5 0.083 12.8 0.1 2.5 2 1 0 2 2 2 2 LYAR-type C2HC zinc finger zf-met PF12874.7 KFQ91950.1 - 0.00036 20.8 3.5 0.29 11.6 0.3 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type XPA_N PF01286.18 KFQ91950.1 - 0.00052 20.0 3.4 0.12 12.4 0.1 2.2 2 0 0 2 2 2 2 XPA protein N-terminal Zn-ribbon_8 PF09723.10 KFQ91950.1 - 0.00088 19.3 3.8 0.023 14.8 4.7 2.1 1 1 1 2 2 2 2 Zinc ribbon domain zf_UBZ PF18439.1 KFQ91950.1 - 0.001 18.6 0.3 1.2 8.7 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger CpXC PF14353.6 KFQ91950.1 - 0.0049 16.9 0.4 0.32 11.0 0.0 2.0 1 1 1 2 2 2 1 CpXC protein zf_C2H2_ZHX PF18387.1 KFQ91950.1 - 0.0053 16.4 2.4 0.15 11.7 0.2 2.1 1 1 1 2 2 2 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-BED PF02892.15 KFQ91950.1 - 0.0062 16.5 5.3 0.36 10.9 0.5 2.1 1 1 1 2 2 2 2 BED zinc finger LIM PF00412.22 KFQ91950.1 - 0.0077 16.4 1.1 0.013 15.7 1.1 1.4 1 1 0 1 1 1 1 LIM domain zf-C2H2_11 PF16622.5 KFQ91950.1 - 0.0079 15.9 3.5 0.73 9.6 0.2 2.2 2 0 0 2 2 2 2 zinc-finger C2H2-type TFIIS_C PF01096.18 KFQ91950.1 - 0.01 15.7 5.1 1.2 9.0 0.9 2.2 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) C1_4 PF07975.12 KFQ91950.1 - 0.01 16.1 1.9 0.019 15.2 1.9 1.5 1 1 0 1 1 1 0 TFIIH C1-like domain YhfH PF14149.6 KFQ91950.1 - 0.018 15.0 4.5 1.2 9.1 0.1 2.2 2 0 0 2 2 2 0 YhfH-like protein HNH PF01844.23 KFQ91950.1 - 0.02 15.0 1.6 4.7 7.5 0.1 2.2 2 0 0 2 2 2 0 HNH endonuclease zf_C2H2_13 PF18508.1 KFQ91950.1 - 0.02 14.4 0.4 0.69 9.6 0.1 2.1 2 0 0 2 2 2 0 Zinc finger domain Zn_ribbon_SprT PF17283.2 KFQ91950.1 - 0.021 14.7 0.7 1 9.3 0.1 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-C2H2_3rep PF18868.1 KFQ91950.1 - 0.025 15.3 0.3 2 9.1 0.1 2.0 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats DZR PF12773.7 KFQ91950.1 - 0.027 14.5 0.4 0.039 14.0 0.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon DNA_RNApol_7kD PF03604.13 KFQ91950.1 - 0.034 13.8 1.6 3.7 7.3 0.4 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_15 PF17032.5 KFQ91950.1 - 0.042 14.6 0.9 0.049 14.4 0.9 1.1 1 0 0 1 1 1 0 zinc-ribbon family zf-C2HE PF16278.5 KFQ91950.1 - 0.043 14.3 6.2 0.65 10.5 1.4 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-ribbon_3 PF13248.6 KFQ91950.1 - 0.049 13.1 2.2 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_8 PF15909.5 KFQ91950.1 - 0.076 13.3 1.0 0.15 12.3 1.0 1.5 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 KFQ91950.1 - 0.12 12.7 2.4 0.26 11.7 0.4 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-UBP PF02148.19 KFQ91950.1 - 0.19 12.1 2.4 1.1 9.6 2.4 1.9 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Rubredoxin_2 PF18073.1 KFQ91950.1 - 0.28 11.0 5.1 3.8 7.3 0.3 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain C1_1 PF00130.22 KFQ91950.1 - 0.41 10.6 4.6 1.9 8.4 4.6 2.0 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_5 PF13909.6 KFQ91950.1 - 0.46 10.3 13.3 2.8 7.8 0.7 3.3 3 1 0 3 3 3 0 C2H2-type zinc-finger domain Zn_Tnp_IS1595 PF12760.7 KFQ91950.1 - 1.1 9.2 4.9 15 5.7 4.9 2.1 1 1 0 1 1 1 0 Transposase zinc-ribbon domain DUF4342 PF14242.6 KFQ91951.1 - 1.5 8.9 4.3 2.7 8.0 2.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4342) zf-H2C2_2 PF13465.6 KFQ91952.1 - 4.9e-66 216.4 63.1 6.8e-09 35.8 0.6 8.9 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ91952.1 - 1.6e-52 173.2 77.5 1e-07 32.0 0.5 8.3 9 0 0 9 9 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ91952.1 - 1e-31 106.9 63.8 4e-05 24.1 0.4 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf_UBZ PF18439.1 KFQ91952.1 - 1.6e-15 56.4 32.9 0.068 12.8 0.1 8.2 8 0 0 8 8 8 8 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFQ91952.1 - 1.2e-11 44.5 36.8 0.0058 16.7 1.7 5.8 3 2 3 6 6 6 6 Zinc ribbon domain zf-C2H2_jaz PF12171.8 KFQ91952.1 - 5.3e-10 39.3 30.1 0.074 13.4 0.3 7.3 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 KFQ91952.1 - 2.8e-08 33.5 36.8 0.21 11.5 0.2 8.3 8 0 0 8 8 8 3 LYAR-type C2HC zinc finger zf-C2H2_11 PF16622.5 KFQ91952.1 - 5.6e-08 32.4 44.8 0.00056 19.6 0.5 8.1 8 0 0 8 8 8 3 zinc-finger C2H2-type C1_1 PF00130.22 KFQ91952.1 - 4.8e-07 29.6 30.0 0.19 11.7 0.8 6.4 1 1 7 8 8 8 6 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-trcl PF13451.6 KFQ91952.1 - 1.5e-06 28.0 30.9 2.8 7.9 0.2 8.1 8 0 0 8 8 8 2 Probable zinc-ribbon domain XPA_N PF01286.18 KFQ91952.1 - 5.1e-06 26.4 31.1 2.1 8.5 0.3 8.1 8 0 0 8 8 8 3 XPA protein N-terminal zinc_ribbon_15 PF17032.5 KFQ91952.1 - 6.7e-06 26.8 29.0 0.015 16.0 1.5 4.7 1 1 6 7 7 7 7 zinc-ribbon family DZR PF12773.7 KFQ91952.1 - 1.5e-05 24.9 35.9 0.26 11.3 7.1 5.1 1 1 1 2 2 1 1 Double zinc ribbon FYDLN_acid PF09538.10 KFQ91952.1 - 2.4e-05 24.9 20.2 5.1 7.8 0.0 7.3 1 1 4 6 6 6 0 Protein of unknown function (FYDLN_acid) LIM PF00412.22 KFQ91952.1 - 4.6e-05 23.5 32.6 0.23 11.7 3.1 5.8 1 1 4 6 6 6 3 LIM domain DNA_RNApol_7kD PF03604.13 KFQ91952.1 - 8.3e-05 22.2 36.4 3 7.6 0.1 8.1 7 1 0 7 7 7 2 DNA directed RNA polymerase, 7 kDa subunit zf-met PF12874.7 KFQ91952.1 - 0.00051 20.3 51.3 0.049 14.0 0.6 7.7 8 0 0 8 8 7 4 Zinc-finger of C2H2 type YhfH PF14149.6 KFQ91952.1 - 0.00069 19.5 28.3 7.7 6.6 0.1 7.9 8 0 0 8 8 8 0 YhfH-like protein MBD PF01429.19 KFQ91952.1 - 0.0015 18.2 2.5 3.6 7.4 0.0 3.7 1 1 1 3 3 3 2 Methyl-CpG binding domain HypA PF01155.19 KFQ91952.1 - 0.002 18.1 27.0 1.3 9.1 1.6 4.8 1 1 3 4 4 4 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CpXC PF14353.6 KFQ91952.1 - 0.0031 17.5 29.2 2.8 8.0 0.1 7.7 4 2 4 8 8 8 1 CpXC protein DUF3268 PF11672.8 KFQ91952.1 - 0.0047 17.2 25.7 1 9.7 1.7 5.0 2 2 5 7 7 7 4 zinc-finger-containing domain ADK_lid PF05191.14 KFQ91952.1 - 0.0056 16.6 36.6 0.21 11.6 2.1 6.4 2 1 4 6 6 6 2 Adenylate kinase, active site lid DUF2256 PF10013.9 KFQ91952.1 - 0.0092 16.1 25.1 13 6.0 0.0 7.7 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn_Tnp_IS1595 PF12760.7 KFQ91952.1 - 0.01 15.8 46.7 0.23 11.5 3.6 5.7 3 3 4 7 7 7 0 Transposase zinc-ribbon domain zf-Di19 PF05605.12 KFQ91952.1 - 0.011 16.0 36.2 0.46 10.8 3.3 5.6 1 1 1 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_ZHX PF18387.1 KFQ91952.1 - 0.018 14.7 37.9 0.76 9.5 0.7 7.3 1 1 7 8 8 8 0 Zinc-fingers and homeoboxes C2H2 finger domain Yippee-Mis18 PF03226.14 KFQ91952.1 - 0.029 14.6 26.7 1.3 9.2 0.8 5.6 3 2 2 5 5 5 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C2H2_6 PF13912.6 KFQ91952.1 - 0.031 14.3 0.3 0.031 14.3 0.3 9.1 8 3 0 8 8 8 0 C2H2-type zinc finger OSTMP1 PF09777.9 KFQ91952.1 - 0.059 12.8 13.7 0.72 9.2 11.8 2.7 1 1 1 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor zf-AN1 PF01428.16 KFQ91952.1 - 0.29 11.3 49.2 1.1 9.4 0.2 8.2 5 2 3 8 8 8 0 AN1-like Zinc finger DUF2072 PF09845.9 KFQ91952.1 - 0.35 11.1 33.3 2 8.6 0.5 7.2 5 3 2 7 7 7 0 Zn-ribbon containing protein C1_4 PF07975.12 KFQ91952.1 - 0.67 10.2 35.0 0.39 11.0 0.6 6.0 1 1 7 8 8 8 0 TFIIH C1-like domain zf-Paramyx-P PF13008.7 KFQ91952.1 - 1.5 8.4 29.3 14 5.3 0.3 7.7 8 0 0 8 8 8 0 Zinc-binding domain of Paramyxoviridae V protein zf_ZIC PF18366.1 KFQ91952.1 - 1.7 8.8 21.7 21 5.3 0.4 6.5 3 2 4 7 7 7 0 Zic proteins zinc finger domain TFIIS_C PF01096.18 KFQ91952.1 - 2.3 8.1 40.8 6.7 6.7 0.2 8.0 7 1 0 7 7 7 0 Transcription factor S-II (TFIIS) Zn_ribbon_recom PF13408.6 KFQ91952.1 - 3.1 8.4 43.4 4.5 7.9 3.0 7.0 1 1 6 7 7 7 0 Recombinase zinc beta ribbon domain BolA PF01722.18 KFQ91952.1 - 5.8 7.3 9.8 9 6.7 0.2 3.6 3 1 1 4 4 4 0 BolA-like protein zf-C2H2 PF00096.26 KFQ91954.1 - 0.0049 17.2 0.8 0.54 10.8 0.1 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ91954.1 - 0.021 15.2 0.5 0.053 14.0 0.5 1.8 1 1 0 1 1 1 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ91954.1 - 0.04 14.8 2.8 3.4 8.8 0.4 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger RhoGEF PF00621.20 KFQ91955.1 - 2.4e-36 125.7 2.7 5.1e-36 124.6 2.7 1.6 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.28 KFQ91955.1 - 6.8e-11 41.6 0.0 1.5e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFQ91955.1 - 4e-10 39.4 0.0 8.8e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFQ91955.1 - 1e-08 34.7 0.0 1.7e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Homeodomain PF00046.29 KFQ91956.1 - 1.7e-23 82.2 2.2 2.4e-23 81.7 2.2 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ91956.1 - 0.00032 20.6 0.1 0.00078 19.3 0.0 1.7 2 0 0 2 2 2 1 Homeobox KN domain HTH_28 PF13518.6 KFQ91956.1 - 0.024 14.7 0.1 0.043 13.9 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1510 PF07423.11 KFQ91956.1 - 0.026 14.6 0.0 0.029 14.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1510) DUF1323 PF07037.11 KFQ91956.1 - 0.033 14.6 0.5 0.052 13.9 0.5 1.3 1 0 0 1 1 1 0 Putative transcription regulator (DUF1323) VWD PF00094.25 KFQ91957.1 - 1.2e-118 392.8 19.5 1.2e-37 129.6 0.4 4.6 4 0 0 4 4 4 4 von Willebrand factor type D domain VWA PF00092.28 KFQ91957.1 - 1.1e-88 296.1 7.9 4.6e-36 124.7 0.4 3.2 3 0 0 3 3 3 3 von Willebrand factor type A domain C8 PF08742.11 KFQ91957.1 - 8.8e-56 186.2 58.1 2.5e-19 69.5 8.4 8.9 8 1 1 9 9 9 4 C8 domain VWA_2 PF13519.6 KFQ91957.1 - 1.4e-31 109.3 1.6 8.3e-11 42.5 0.1 3.4 3 0 0 3 3 3 3 von Willebrand factor type A domain TIL PF01826.17 KFQ91957.1 - 1.3e-27 95.8 111.4 2.8e-12 46.7 18.8 20.1 17 3 5 22 22 22 5 Trypsin Inhibitor like cysteine rich domain VWC PF00093.18 KFQ91957.1 - 1.8e-08 34.5 59.5 2.1e-06 28.0 15.1 21.1 14 4 7 21 21 21 5 von Willebrand factor type C domain MCR_beta_N PF02783.15 KFQ91957.1 - 0.0037 16.9 0.0 0.0069 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyl-coenzyme M reductase beta subunit, N-terminal domain Anoctamin PF04547.12 KFQ91959.1 - 3.2e-156 520.7 10.4 4e-156 520.3 10.4 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KFQ91959.1 - 2.4e-80 269.5 0.1 5.5e-80 268.3 0.1 1.7 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin NGF PF00243.18 KFQ91960.1 - 9e-52 174.1 3.7 1.6e-51 173.3 3.7 1.4 1 0 0 1 1 1 1 Nerve growth factor family Spaetzle PF16077.5 KFQ91960.1 - 0.0006 20.3 0.5 0.0006 20.3 0.5 1.7 2 0 0 2 2 2 1 Spaetzle Ion_trans PF00520.31 KFQ91961.1 - 1.8e-54 184.6 0.2 2.3e-54 184.2 0.2 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFQ91961.1 - 2.6e-23 82.2 0.1 4.6e-23 81.4 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFQ91961.1 - 3.4e-14 52.6 4.1 3.4e-14 52.6 4.1 2.3 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.12 KFQ91961.1 - 0.00085 18.1 0.9 0.0019 16.9 0.9 1.5 1 0 0 1 1 1 1 Polycystin cation channel Sigma_reg_N PF13800.6 KFQ91961.1 - 0.2 11.9 1.0 7.9 6.9 0.0 3.2 3 0 0 3 3 3 0 Sigma factor regulator N-terminal ELO PF01151.18 KFQ91962.1 - 8.2e-65 218.8 22.8 9.2e-65 218.6 22.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF3290 PF11694.8 KFQ91962.1 - 0.063 13.3 2.9 0.17 11.8 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Insulin_TMD PF17870.1 KFQ91962.1 - 0.089 12.9 2.0 4.2 7.5 0.1 2.6 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Ion_trans PF00520.31 KFQ91963.1 - 2.9e-52 177.3 11.1 4.1e-52 176.9 11.1 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFQ91963.1 - 1.5e-28 99.0 0.3 3.7e-28 97.7 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFQ91963.1 - 6.2e-14 51.7 5.2 6.2e-14 51.7 5.2 2.8 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.12 KFQ91963.1 - 0.012 14.4 0.5 0.012 14.4 0.5 1.8 1 1 1 2 2 2 0 Polycystin cation channel Sigma_reg_N PF13800.6 KFQ91963.1 - 0.16 12.2 8.1 4.6 7.6 0.1 3.8 3 1 0 3 3 3 0 Sigma factor regulator N-terminal DUF423 PF04241.15 KFQ91963.1 - 5 7.4 4.9 1.3 9.3 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF423) Ion_trans PF00520.31 KFQ91964.1 - 1.6e-51 174.9 0.1 2.2e-51 174.5 0.1 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFQ91964.1 - 8.5e-17 61.3 0.3 1.5e-16 60.5 0.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFQ91964.1 - 1.4e-12 47.4 7.0 1.4e-12 47.4 7.0 2.6 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.12 KFQ91964.1 - 0.0061 15.3 2.8 0.013 14.3 2.8 1.6 1 1 0 1 1 1 1 Polycystin cation channel DUF423 PF04241.15 KFQ91964.1 - 0.12 12.6 0.5 0.95 9.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF423) Sigma_reg_N PF13800.6 KFQ91964.1 - 0.43 10.9 2.8 8.5 6.7 0.1 3.3 3 0 0 3 3 3 0 Sigma factor regulator N-terminal DUF973 PF06157.11 KFQ91964.1 - 1.3 8.0 8.8 0.086 11.9 3.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF973) Glycos_transf_2 PF00535.26 KFQ91965.1 - 2.6e-21 76.2 0.1 4e-21 75.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFQ91965.1 - 9.6e-13 48.5 0.0 1.6e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 KFQ91965.1 - 0.02 14.5 0.0 0.048 13.3 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase 3Beta_HSD PF01073.19 KFQ91966.1 - 9.5e-13 47.8 0.0 1.7e-09 37.1 0.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFQ91966.1 - 2.7e-11 43.4 0.0 8.2e-10 38.6 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KFQ91966.1 - 3.8e-10 39.7 0.0 3.2e-09 36.7 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFQ91966.1 - 9.9e-09 35.3 0.0 2.1e-08 34.3 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KFQ91966.1 - 1.2e-07 31.2 0.0 8.5e-06 25.1 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KFQ91966.1 - 3.4e-05 23.2 0.0 0.13 11.4 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KFQ91966.1 - 0.0074 15.7 0.0 0.038 13.4 0.0 2.0 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase Cyclin_N PF00134.23 KFQ91967.1 - 3.5e-37 127.0 1.3 6.7e-37 126.1 1.3 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFQ91967.1 - 5.6e-22 78.1 0.2 4.3e-21 75.2 0.0 2.2 2 1 0 2 2 2 1 Cyclin, C-terminal domain K-cyclin_vir_C PF09080.10 KFQ91967.1 - 0.021 15.2 0.0 0.036 14.5 0.0 1.3 1 0 0 1 1 1 0 K cyclin, C terminal SbcD_C PF12320.8 KFQ91967.1 - 0.099 13.0 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain FGF PF00167.18 KFQ91968.1 - 6.4e-23 81.2 0.0 8.8e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Fibroblast growth factor FGF PF00167.18 KFQ91969.1 - 2.7e-40 137.3 0.0 3.4e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Fibroblast growth factor DUF2362 PF10154.9 KFQ91970.1 - 2e-218 726.4 14.3 2.3e-218 726.2 14.3 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) RAD51_interact PF15696.5 KFQ91971.1 - 1.6e-20 72.9 1.5 1.6e-20 72.9 1.5 2.3 3 0 0 3 3 3 1 RAD51 interacting motif Pkinase PF00069.25 KFQ91973.1 - 2.1e-56 191.2 0.0 2.6e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ91973.1 - 5.6e-19 68.4 0.0 7.9e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFQ91973.1 - 0.00019 21.5 0.0 0.00045 20.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFQ91973.1 - 0.0037 16.9 0.0 0.0084 15.7 0.0 1.6 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KFQ91973.1 - 0.011 15.4 0.8 0.016 14.8 0.8 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 KFQ91973.1 - 0.025 13.9 0.1 0.13 11.5 0.0 1.9 1 1 1 2 2 2 0 Kinase-like AChE_tetra PF08674.10 KFQ91974.1 - 7.7e-24 83.1 7.9 1.4e-23 82.3 7.9 1.4 1 0 0 1 1 1 1 Acetylcholinesterase tetramerisation domain COesterase PF00135.28 KFQ91974.1 - 0.012 14.5 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family DLP_helical PF18709.1 KFQ91974.1 - 0.065 12.4 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Dynamin-like helical domain CENP-Q PF13094.6 KFQ91976.1 - 0.0055 16.9 5.3 0.0066 16.7 5.3 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit TMCO5 PF14992.6 KFQ91976.1 - 0.093 12.3 6.1 0.11 12.1 6.1 1.2 1 0 0 1 1 1 0 TMCO5 family LMBR1 PF04791.16 KFQ91976.1 - 0.2 10.5 2.0 0.2 10.5 2.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4482 PF14818.6 KFQ91976.1 - 0.5 11.2 10.3 0.68 10.8 10.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4482) KLRAQ PF10205.9 KFQ91976.1 - 0.73 10.1 11.8 0.89 9.8 10.5 1.8 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein YabA PF06156.13 KFQ91976.1 - 0.87 10.3 6.7 0.94 10.1 3.2 2.0 2 0 0 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 KFQ91976.1 - 1.7 9.1 14.5 0.22 12.0 9.7 1.8 2 0 0 2 2 2 0 Cell division protein ZapB TMPIT PF07851.13 KFQ91976.1 - 1.7 7.8 6.1 2.1 7.5 6.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF1241 PF06840.11 KFQ91977.1 - 2.1e-63 212.4 3.2 2.9e-63 212.0 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) FH2 PF02181.23 KFQ91977.1 - 0.00072 18.8 2.0 0.00072 18.8 2.0 1.5 1 1 0 1 1 1 1 Formin Homology 2 Domain CENP-L PF13092.6 KFQ91977.1 - 0.0094 16.2 0.1 0.011 15.9 0.1 1.3 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 CREPT PF16566.5 KFQ91977.1 - 0.018 15.2 0.8 0.032 14.4 0.8 1.5 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Med11 PF10280.9 KFQ91977.1 - 0.028 14.9 1.1 0.077 13.5 0.4 2.0 1 1 2 3 3 3 0 Mediator complex protein SabA_adhesion PF18304.1 KFQ91977.1 - 0.049 12.9 0.6 0.069 12.4 0.6 1.2 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain DUF4208 PF13907.6 KFQ91977.1 - 0.06 13.8 1.1 20 5.7 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4208) DUF5344 PF17279.2 KFQ91977.1 - 0.069 13.7 1.5 0.24 12.0 0.6 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5344) GCN5L1 PF06320.13 KFQ91977.1 - 0.073 13.2 1.8 0.59 10.3 0.9 2.2 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) SesA PF17107.5 KFQ91977.1 - 0.076 13.2 2.3 0.1 12.8 0.9 2.0 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Sec23_trunk PF04811.15 KFQ91977.1 - 0.086 12.4 1.2 2.4 7.7 1.3 2.6 1 1 0 1 1 1 0 Sec23/Sec24 trunk domain Syntaxin_2 PF14523.6 KFQ91977.1 - 0.12 12.8 5.7 0.4 11.1 5.7 1.9 1 1 0 1 1 1 0 Syntaxin-like protein TFIIF_beta PF02270.15 KFQ91977.1 - 0.14 12.3 1.0 0.44 10.7 0.3 2.2 2 0 0 2 2 2 0 TFIIF, beta subunit HTH domain NAAA-beta PF15508.6 KFQ91977.1 - 0.2 12.0 0.7 2.8 8.3 0.1 2.7 3 0 0 3 3 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Serpin PF00079.20 KFQ91978.1 - 3.9e-115 385.1 1.2 4.4e-115 384.9 1.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF1280 PF06918.14 KFQ91978.1 - 0.061 12.9 0.4 0.1 12.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) LRR_9 PF14580.6 KFQ91979.1 - 4.7e-06 26.2 0.9 9.8e-06 25.2 0.7 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KFQ91979.1 - 1.4e-05 25.3 9.4 0.0014 19.0 0.3 4.0 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFQ91979.1 - 0.00052 19.7 7.3 0.058 13.2 0.5 3.6 1 1 2 3 3 3 3 Leucine rich repeat HARE-HTH PF05066.13 KFQ91980.1 - 0.097 13.1 1.0 0.38 11.2 1.0 2.0 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain DUF4525 PF15027.6 KFQ91980.1 - 0.38 10.5 3.9 0.12 12.1 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) DUF948 PF06103.11 KFQ91980.1 - 1.7 8.9 3.2 14 6.0 1.5 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PI_PP_I PF18363.1 KFQ91980.1 - 3.2 8.0 8.4 0.47 10.7 2.6 2.6 2 1 0 2 2 2 0 Phosphoinositide phosphatase insertion domain zf-C2H2 PF00096.26 KFQ91982.1 - 9.5e-50 164.4 78.0 5.2e-07 29.8 1.4 10.6 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ91982.1 - 6.9e-33 110.5 73.0 0.00083 20.0 0.6 10.7 10 0 0 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFQ91982.1 - 1e-32 111.1 71.8 2.9e-08 33.8 1.2 11.8 12 0 0 12 12 11 6 Zinc-finger double domain zf-C2H2_6 PF13912.6 KFQ91982.1 - 1.4e-13 50.5 64.4 8.8e-05 22.4 0.2 10.1 10 0 0 10 10 10 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ91982.1 - 2.7e-11 43.4 56.7 0.0027 17.9 0.8 10.9 11 0 0 11 11 11 6 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFQ91982.1 - 1.9e-06 27.5 61.9 4.3e-05 23.2 2.4 9.1 9 1 0 9 9 9 5 C2H2-type zinc-finger domain zf-BED PF02892.15 KFQ91982.1 - 0.00064 19.7 0.5 0.00064 19.7 0.5 7.7 3 3 5 8 8 8 3 BED zinc finger zf-C2H2_8 PF15909.5 KFQ91982.1 - 0.0016 18.7 39.8 0.11 12.9 7.5 5.8 2 1 3 5 5 5 3 C2H2-type zinc ribbon GAGA PF09237.11 KFQ91982.1 - 0.0069 16.2 19.2 2.5 8.0 0.2 5.7 3 1 2 5 5 5 3 GAGA factor Zn-ribbon_8 PF09723.10 KFQ91982.1 - 0.0081 16.3 1.6 0.0081 16.3 1.6 7.9 7 2 0 7 7 7 2 Zinc ribbon domain zf-C2H2_11 PF16622.5 KFQ91982.1 - 0.017 14.9 57.4 0.05 13.4 0.8 8.5 10 0 0 10 10 9 0 zinc-finger C2H2-type zf-met PF12874.7 KFQ91982.1 - 0.034 14.5 48.2 0.37 11.3 0.2 9.6 9 0 0 9 9 9 0 Zinc-finger of C2H2 type PyrI_C PF02748.15 KFQ91982.1 - 0.35 10.8 0.0 0.35 10.8 0.0 6.8 6 1 1 7 7 7 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zinc_ribbon_15 PF17032.5 KFQ91982.1 - 7.5 7.4 45.0 0.23 12.2 0.6 6.4 2 2 6 8 8 8 0 zinc-ribbon family zf-H2C2_2 PF13465.6 KFQ91984.1 - 2.9e-53 176.0 46.7 2.3e-09 37.2 0.2 9.3 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ91984.1 - 5.4e-37 124.2 53.2 5.1e-06 26.7 0.5 8.6 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ91984.1 - 1.8e-31 106.1 51.8 0.00075 20.1 2.1 8.9 8 0 0 8 8 8 8 C2H2-type zinc finger BTB PF00651.31 KFQ91984.1 - 1.2e-23 83.5 0.2 3e-23 82.2 0.2 1.7 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_6 PF13912.6 KFQ91984.1 - 2.4e-12 46.5 45.2 0.022 14.8 0.2 8.6 8 1 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ91984.1 - 8.3e-11 41.9 33.0 0.0031 17.8 0.2 8.4 9 0 0 9 9 8 5 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFQ91984.1 - 4.3e-07 29.6 36.4 0.08 12.7 0.5 8.5 8 0 0 8 8 8 2 C2H2-type zinc-finger domain zf-met PF12874.7 KFQ91984.1 - 9.2e-07 29.1 52.6 0.0026 18.1 0.5 9.0 9 0 0 9 9 9 4 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFQ91984.1 - 3.7e-05 23.9 30.3 0.051 13.9 0.5 5.5 3 1 2 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf-MYST PF17772.1 KFQ91984.1 - 0.00086 18.9 21.2 6.1 6.5 0.1 8.2 8 1 1 9 9 9 1 MYST family zinc finger domain zf-C2H2_11 PF16622.5 KFQ91984.1 - 0.0014 18.4 36.8 0.0016 18.2 0.4 8.2 8 0 0 8 8 8 1 zinc-finger C2H2-type zf_UBZ PF18439.1 KFQ91984.1 - 0.0077 15.8 26.3 0.38 10.4 0.1 7.8 8 0 0 8 8 8 2 Ubiquitin-Binding Zinc Finger zf-C2H2_8 PF15909.5 KFQ91984.1 - 0.0078 16.5 22.1 0.1 12.9 6.8 4.7 1 1 4 5 5 5 1 C2H2-type zinc ribbon DUF3268 PF11672.8 KFQ91984.1 - 0.016 15.5 19.9 0.4 11.0 0.6 4.4 3 1 1 4 4 4 0 zinc-finger-containing domain Zn-ribbon_8 PF09723.10 KFQ91984.1 - 0.018 15.1 30.9 0.79 9.9 2.3 6.8 2 1 5 7 7 7 0 Zinc ribbon domain DUF3342 PF11822.8 KFQ91984.1 - 0.033 14.4 0.3 0.28 11.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) zf_C2H2_13 PF18508.1 KFQ91984.1 - 0.034 13.7 8.9 4.2 7.0 0.0 5.2 5 0 0 5 5 5 0 Zinc finger domain ADK_lid PF05191.14 KFQ91984.1 - 0.058 13.4 30.0 2 8.5 0.7 6.4 4 2 2 6 6 5 0 Adenylate kinase, active site lid zf-BED PF02892.15 KFQ91984.1 - 0.096 12.7 0.2 0.096 12.7 0.2 7.3 4 2 4 8 8 7 0 BED zinc finger Zn_ribbon_SprT PF17283.2 KFQ91984.1 - 0.11 12.5 22.5 0.22 11.5 0.3 5.1 4 1 1 5 5 5 0 SprT-like zinc ribbon domain zf_C2H2_ZHX PF18387.1 KFQ91984.1 - 0.2 11.3 0.1 0.2 11.3 0.1 7.2 4 1 4 8 8 8 0 Zinc-fingers and homeoboxes C2H2 finger domain zinc_ribbon_15 PF17032.5 KFQ91984.1 - 0.21 12.4 32.0 0.57 11.0 1.9 5.5 1 1 3 6 6 6 0 zinc-ribbon family Vps36-NZF-N PF16988.5 KFQ91984.1 - 0.42 10.1 15.0 6 6.3 0.3 5.0 3 1 2 5 5 5 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain GAGA PF09237.11 KFQ91984.1 - 0.91 9.4 11.1 28 4.6 0.1 5.1 2 2 5 7 7 7 0 GAGA factor zf-C2H2_9 PF16293.5 KFQ91984.1 - 1.5 8.7 9.2 25 4.8 0.0 5.6 6 0 0 6 6 6 0 C2H2 type zinc-finger (1 copy) FYVE PF01363.21 KFQ91984.1 - 3.5 7.8 34.8 11 6.3 2.6 5.4 1 1 4 5 5 5 0 FYVE zinc finger XPA_N PF01286.18 KFQ91984.1 - 5.2 7.2 26.6 6.6 6.9 0.0 7.2 8 0 0 8 8 7 0 XPA protein N-terminal C1_4 PF07975.12 KFQ91984.1 - 6 7.2 29.3 2 8.7 6.3 5.6 1 1 4 6 6 6 0 TFIIH C1-like domain zf-C2H2_3rep PF18868.1 KFQ91984.1 - 7.5 7.3 30.9 2.6 8.7 0.7 6.1 2 1 3 5 5 4 0 Zinc finger C2H2-type, 3 repeats LRR_4 PF12799.7 KFQ91985.1 - 8.3e-18 64.2 43.0 0.0027 18.1 2.0 9.2 2 1 11 13 13 13 13 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFQ91985.1 - 1.5e-15 55.9 36.0 0.0068 16.4 0.0 13.7 14 0 0 14 14 14 7 Leucine Rich repeat LRR_1 PF00560.33 KFQ91985.1 - 1.2e-09 37.4 39.8 1.1 10.1 0.2 13.5 13 2 0 13 13 13 4 Leucine Rich Repeat LRR_8 PF13855.6 KFQ91985.1 - 1.4e-07 31.2 38.6 0.13 12.0 0.7 9.9 4 2 7 11 11 11 9 Leucine rich repeat SAM_1 PF00536.30 KFQ91986.1 - 3.6e-13 49.7 0.0 6.7e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFQ91986.1 - 7.4e-09 35.6 0.0 1.6e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Presenilin PF01080.17 KFQ91986.1 - 0.25 10.1 0.1 0.29 9.9 0.1 1.2 1 0 0 1 1 1 0 Presenilin Sec62 PF03839.16 KFQ91987.1 - 1.2e-77 260.3 3.9 1.2e-77 260.3 3.9 2.3 1 1 1 2 2 2 1 Translocation protein Sec62 DEP PF00610.21 KFQ91987.1 - 0.011 15.8 0.2 0.029 14.4 0.0 1.8 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Ctr PF04145.15 KFQ91987.1 - 0.38 11.4 0.1 0.38 11.4 0.1 2.6 2 1 0 2 2 2 0 Ctr copper transporter family Dsh_C PF12316.8 KFQ91987.1 - 7.9 6.8 19.5 12 6.2 1.5 2.2 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal BUD22 PF09073.10 KFQ91987.1 - 9.3 5.5 56.0 1.6 8.0 18.2 2.1 2 0 0 2 2 2 0 BUD22 SAM_1 PF00536.30 KFQ91989.1 - 2.3e-15 56.8 0.0 3.9e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFQ91989.1 - 9.1e-09 35.3 0.0 2.2e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFQ91989.1 - 0.0052 16.7 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain zf-FCS PF06467.14 KFQ91989.1 - 0.39 10.7 3.7 1.2 9.1 1.0 2.6 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif VATC PF18716.1 KFQ91989.1 - 1.2 9.1 5.1 2.6 8.0 5.1 1.6 1 0 0 1 1 1 0 Vms1-associating treble clef domain Pkinase PF00069.25 KFQ91990.1 - 2.2e-67 227.2 0.0 3.5e-67 226.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ91990.1 - 2.5e-34 118.8 0.0 3.6e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KFQ91990.1 - 1.3e-14 53.8 9.8 2.6e-14 52.8 9.8 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PB1 PF00564.24 KFQ91990.1 - 6.1e-11 42.1 0.0 1.7e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 PB1 domain Pkinase_C PF00433.24 KFQ91990.1 - 2e-05 25.2 2.3 5.3e-05 23.8 2.3 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFQ91990.1 - 4.1e-05 23.0 0.0 6.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFQ91990.1 - 0.0091 15.0 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain C1_2 PF03107.16 KFQ91990.1 - 0.015 15.6 2.8 0.033 14.5 2.8 1.5 1 0 0 1 1 1 0 C1 domain APH PF01636.23 KFQ91990.1 - 0.03 14.2 0.0 0.094 12.6 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 KFQ91990.1 - 0.031 13.9 0.1 0.79 9.3 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KFQ91990.1 - 0.032 13.6 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ski_Sno PF02437.17 KFQ91991.1 - 4.4e-44 148.6 1.5 1.2e-43 147.3 1.5 1.8 1 0 0 1 1 1 1 SKI/SNO/DAC family c-SKI_SMAD_bind PF08782.10 KFQ91991.1 - 1e-36 125.0 4.1 2.8e-36 123.6 4.1 1.8 1 0 0 1 1 1 1 c-SKI Smad4 binding domain DUF489 PF04356.12 KFQ91991.1 - 0.27 11.2 9.7 0.2 11.6 7.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF489) PMP22_Claudin PF00822.20 KFQ91992.1 - 1.6e-17 63.9 8.9 2.7e-17 63.1 8.9 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFQ91992.1 - 0.0025 17.6 15.4 0.32 10.7 15.4 2.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction AA_permease_2 PF13520.6 KFQ91993.1 - 4.3e-46 157.6 57.2 9e-45 153.3 38.9 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 KFQ91993.1 - 2.1e-35 122.2 37.8 2.1e-35 122.2 37.8 2.4 2 1 0 2 2 2 2 Amino acid permease AA_permease_C PF13906.6 KFQ91993.1 - 1.7e-20 72.8 9.9 1.7e-20 72.8 9.9 4.5 4 0 0 4 4 4 1 C-terminus of AA_permease Ribosomal_L22e PF01776.17 KFQ91994.1 - 1.7e-44 150.7 6.3 4.8e-44 149.2 6.3 1.6 1 1 0 1 1 1 1 Ribosomal L22e protein family eIF-5a PF01287.20 KFQ91995.1 - 3.5e-28 97.5 0.2 4.4e-28 97.2 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Sugar_tr PF00083.24 KFQ91996.1 - 6.2e-150 500.0 21.9 7.6e-150 499.7 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFQ91996.1 - 3.8e-21 75.4 38.2 9.4e-18 64.3 26.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sigma70_ner PF04546.13 KFQ91996.1 - 0.11 12.4 0.7 0.15 11.9 0.7 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CNH PF00780.22 KFQ91997.1 - 1.6e-60 205.1 0.0 2.6e-60 204.4 0.0 1.3 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.25 KFQ91997.1 - 2.4e-58 197.6 0.0 7.1e-58 196.0 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ91997.1 - 6.3e-44 150.2 0.0 1.3e-43 149.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase fn3 PF00041.21 KFQ91998.1 - 1.6e-89 294.3 3.0 4.2e-11 43.0 0.0 9.9 9 1 0 9 9 9 9 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFQ91998.1 - 2.4e-21 76.1 3.5 0.21 12.2 0.1 8.7 8 1 0 8 8 8 7 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 KFQ91998.1 - 3.5e-13 49.7 0.0 0.046 14.1 0.0 7.1 7 0 0 7 7 7 5 Uncharacterised conserved protein (DUF2369) Interfer-bind PF09294.10 KFQ91998.1 - 1.1e-09 38.5 6.1 5 7.5 0.0 7.7 8 0 0 8 8 8 4 Interferon-alpha/beta receptor, fibronectin type III fn3_2 PF16893.5 KFQ91998.1 - 0.00027 21.0 0.0 3.5 7.8 0.0 5.2 5 0 0 5 5 5 1 Fibronectin type III domain Y_Y_Y PF07495.13 KFQ91998.1 - 0.17 11.9 0.5 11 6.0 0.0 4.0 6 0 0 6 6 6 0 Y_Y_Y domain TNF PF00229.18 KFQ91999.1 - 9e-42 142.0 0.3 1.5e-41 141.3 0.3 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family C1q PF00386.21 KFQ91999.1 - 0.047 13.9 0.9 0.77 10.0 0.0 2.2 1 1 0 2 2 2 0 C1q domain Abhydrolase_3 PF07859.13 KFQ92000.1 - 3.8e-54 183.7 0.1 3.1e-39 135.0 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 KFQ92000.1 - 1.7e-07 30.5 0.0 2.9e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Say1_Mug180 PF10340.9 KFQ92000.1 - 5.6e-07 28.8 0.0 8.5e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KFQ92000.1 - 0.00089 18.8 0.0 0.0026 17.3 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family PuR_N PF09182.10 KFQ92000.1 - 0.0084 16.0 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial purine repressor, N-terminal Chlorophyllase2 PF12740.7 KFQ92000.1 - 0.0098 14.8 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme AXE1 PF05448.12 KFQ92000.1 - 0.019 13.7 0.0 0.028 13.1 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) RhoGEF PF00621.20 KFQ92001.1 - 1.9e-39 135.8 0.4 4e-39 134.7 0.4 1.6 1 0 0 1 1 1 1 RhoGEF domain PTCB-BRCT PF12738.7 KFQ92001.1 - 2.6e-25 88.1 3.9 1.3e-18 66.7 0.1 3.5 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.26 KFQ92001.1 - 5.2e-16 58.8 0.3 5.8e-07 29.8 0.0 3.0 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KFQ92001.1 - 0.00045 20.5 0.0 1.6 9.1 0.1 2.8 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain BRCT_2 PF16589.5 KFQ92001.1 - 0.00084 19.7 0.0 0.018 15.4 0.0 2.7 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KFQ92001.1 - 0.046 13.6 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain NYD-SP12_N PF15015.6 KFQ92002.1 - 6.8e-258 856.7 4.0 8.3e-258 856.4 4.0 1.0 1 0 0 1 1 1 1 Spermatogenesis-associated, N-terminal TPR_2 PF07719.17 KFQ92002.1 - 0.027 14.6 2.0 1.5 9.1 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ92002.1 - 0.12 12.2 0.6 12 6.0 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat COesterase PF00135.28 KFQ92003.1 - 1.8e-125 419.8 0.0 2.2e-125 419.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Sarcoglycan_2 PF05510.13 KFQ92003.1 - 0.015 14.1 0.0 0.034 12.9 0.0 1.5 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon Abhydrolase_3 PF07859.13 KFQ92003.1 - 0.02 14.8 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Leptin PF02024.15 KFQ92004.1 - 0.15 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Leptin FF PF01846.19 KFQ92005.1 - 3.4e-20 71.9 14.2 7.9e-11 42.0 0.9 2.6 3 0 0 3 3 3 2 FF domain WW PF00397.26 KFQ92005.1 - 2.8e-05 24.1 0.1 2.8e-05 24.1 0.1 2.0 2 0 0 2 2 2 1 WW domain Glutaredoxin PF00462.24 KFQ92006.1 - 2.4e-39 133.3 0.1 4e-17 62.2 0.0 3.3 3 0 0 3 3 3 3 Glutaredoxin Thioredoxin PF00085.20 KFQ92006.1 - 1.7e-18 66.5 0.2 1.1e-17 63.9 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 KFQ92006.1 - 1.2e-07 32.1 0.2 8.9e-07 29.3 0.0 2.5 2 2 0 2 2 2 1 Thioredoxin-like domain SH3BGR PF04908.15 KFQ92006.1 - 1.3e-05 25.3 0.0 0.13 12.5 0.0 2.7 2 0 0 2 2 2 2 SH3-binding, glutamic acid-rich protein DIM1 PF02966.16 KFQ92006.1 - 5.2e-05 23.0 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.6 KFQ92006.1 - 0.0004 20.7 0.1 0.1 12.9 0.0 3.6 3 1 1 4 4 4 1 Thioredoxin-like Phosducin PF02114.16 KFQ92006.1 - 0.0004 19.4 0.0 0.00081 18.4 0.0 1.5 1 0 0 1 1 1 1 Phosducin OST3_OST6 PF04756.13 KFQ92006.1 - 0.00066 19.1 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 KFQ92006.1 - 0.00093 19.2 0.5 0.0067 16.5 0.1 2.5 2 1 1 3 3 3 1 Thioredoxin domain HyaE PF07449.11 KFQ92006.1 - 0.0021 18.0 0.0 0.09 12.7 0.0 3.0 2 1 0 3 3 3 1 Hydrogenase-1 expression protein HyaE CTX_RstB PF07459.11 KFQ92006.1 - 0.048 13.9 0.1 7.3 6.9 0.0 3.1 3 0 0 3 3 3 0 CTX phage RstB protein TrbC_Ftype PF09673.10 KFQ92006.1 - 0.11 12.6 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein Cauli_DNA-bind PF03310.13 KFQ92006.1 - 0.13 12.4 0.0 4.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein RdRP PF05183.12 KFQ92006.1 - 0.15 10.7 0.0 7.8 5.0 0.0 2.1 1 1 0 2 2 2 0 RNA dependent RNA polymerase DNA_binding_1 PF01035.20 KFQ92007.1 - 7.5e-27 93.3 0.0 8.9e-27 93.0 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain PP1_bind PF15276.6 KFQ92011.1 - 5.6e-23 81.0 0.8 7.5e-23 80.6 0.8 1.2 1 0 0 1 1 1 1 Protein phosphatase 1 binding FHA PF00498.26 KFQ92012.1 - 8.2e-13 48.5 0.0 1.2e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFQ92012.1 - 2.2e-09 37.5 0.0 3.2e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 KFQ92012.1 - 0.0011 19.1 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 FHA domain Y_phosphatase PF00102.27 KFQ92013.1 - 1.1e-142 473.5 6.5 8.1e-83 277.6 0.9 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 KFQ92013.1 - 0.0008 19.2 0.1 0.0043 16.9 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFQ92013.1 - 0.00085 19.4 0.2 0.0036 17.3 0.0 2.0 3 0 0 3 3 3 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFQ92013.1 - 0.094 12.8 0.0 0.41 10.8 0.0 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate DUF2207 PF09972.9 KFQ92014.1 - 0.099 11.4 5.6 0.085 11.6 3.4 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) ASFV_J13L PF05568.11 KFQ92014.1 - 0.11 12.3 0.3 0.9 9.3 0.1 2.2 2 0 0 2 2 2 0 African swine fever virus J13L protein Telomerase_RBD PF12009.8 KFQ92014.1 - 0.11 12.6 1.0 0.21 11.7 0.1 2.0 2 0 0 2 2 2 0 Telomerase ribonucleoprotein complex - RNA binding domain MadM PF03818.13 KFQ92014.1 - 0.46 10.4 6.1 3.5 7.6 0.7 2.5 2 0 0 2 2 2 0 Malonate/sodium symporter MadM subunit DUF4179 PF13786.6 KFQ92014.1 - 1.3 9.6 4.9 4.7 7.7 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) DUF3671 PF12420.8 KFQ92014.1 - 2.5 8.2 10.5 1.2 9.3 0.4 2.9 1 1 1 3 3 3 0 Protein of unknown function DHR-2 PF06920.13 KFQ92015.1 - 3.4e-81 273.5 3.9 4.2e-81 273.2 3.9 1.1 1 0 0 1 1 1 1 Dock homology region 2 SR-25 PF10500.9 KFQ92015.1 - 0.033 13.8 10.3 0.053 13.1 10.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAM196 PF15265.6 KFQ92017.1 - 1.1e-209 698.0 18.2 1.3e-209 697.8 18.2 1.0 1 0 0 1 1 1 1 FAM196 family CX PF01705.19 KFQ92017.1 - 0.14 12.7 0.9 8.3 7.0 0.0 2.7 2 0 0 2 2 2 0 CX module Flu_C_NS2 PF03555.14 KFQ92018.1 - 0.16 12.1 0.2 0.24 11.6 0.2 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS2) DOCK-C2 PF14429.6 KFQ92019.1 - 2.4e-38 131.9 0.0 3e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DOCK_N PF16172.5 KFQ92019.1 - 4.5e-14 52.2 0.0 6.4e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 DOCK N-terminus Centro_C10orf90 PF17730.1 KFQ92020.1 - 1e-229 763.6 17.8 1.3e-229 763.3 17.8 1.1 1 0 0 1 1 1 1 Centrosomal C10orf90 ALMS_motif PF15309.6 KFQ92020.1 - 1.1e-15 58.2 1.8 1.1e-15 58.2 1.8 2.4 2 1 0 2 2 2 1 ALMS motif Reprolysin PF01421.19 KFQ92021.1 - 1.4e-73 247.1 0.0 1.4e-73 247.1 0.0 1.9 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.12 KFQ92021.1 - 4.4e-33 114.1 4.3 4.4e-33 114.1 4.3 3.4 3 1 0 3 3 3 1 ADAM cysteine-rich Pep_M12B_propep PF01562.19 KFQ92021.1 - 1.6e-28 99.7 0.2 1.6e-28 99.7 0.2 1.6 2 0 0 2 2 2 1 Reprolysin family propeptide Reprolysin_5 PF13688.6 KFQ92021.1 - 4.5e-21 75.9 0.0 1.1e-20 74.7 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Disintegrin PF00200.23 KFQ92021.1 - 1.6e-19 70.5 28.2 1.6e-19 70.5 28.2 4.2 3 1 0 4 4 4 1 Disintegrin Reprolysin_3 PF13582.6 KFQ92021.1 - 1.4e-14 54.7 0.0 2.5e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFQ92021.1 - 2.2e-14 53.6 0.0 4.1e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFQ92021.1 - 2.1e-13 50.6 0.0 3.9e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 KFQ92021.1 - 0.063 12.2 0.2 0.1 11.5 0.2 1.2 1 0 0 1 1 1 0 Peptidase M66 Zincin_1 PF06262.11 KFQ92021.1 - 0.1 12.7 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Zincin-like metallopeptidase HA2 PF04408.23 KFQ92022.1 - 5.8e-20 71.6 0.0 1.7e-19 70.1 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFQ92022.1 - 1.1e-11 45.0 0.1 3.7e-11 43.2 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DUF4821 PF16092.5 KFQ92022.1 - 0.13 11.9 1.6 2.1 7.9 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4821) Pox_D2 PF04701.13 KFQ92022.1 - 0.36 11.0 3.2 3.8 7.7 0.1 2.6 2 0 0 2 2 2 0 Pox virus D2 protein BCIP PF13862.6 KFQ92023.1 - 2.4e-62 210.4 4.7 2.8e-62 210.2 4.7 1.0 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Spt5_N PF11942.8 KFQ92023.1 - 0.18 12.8 3.7 0.26 12.3 1.0 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF4611 PF15387.6 KFQ92023.1 - 0.33 11.2 2.7 0.31 11.3 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CBF PF03914.17 KFQ92023.1 - 0.45 10.5 3.0 1.6 8.8 3.0 1.8 1 1 0 1 1 1 0 CBF/Mak21 family HEM4 PF02602.15 KFQ92024.1 - 9.1e-45 152.8 0.0 1e-44 152.6 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD TPR_2 PF07719.17 KFQ92025.1 - 0.54 10.5 11.2 0.66 10.2 0.7 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ92025.1 - 1 9.7 6.2 16 6.0 1.3 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ92025.1 - 6.1 6.8 6.1 6.7 6.7 0.5 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat 2-Hacid_dh_C PF02826.19 KFQ92026.1 - 2.3e-55 186.7 0.0 4.1e-55 185.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFQ92026.1 - 1.2e-29 102.7 0.1 1.5e-29 102.4 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFQ92026.1 - 0.041 14.0 0.0 0.092 12.9 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AnkUBD PF18418.1 KFQ92027.1 - 9e-55 182.8 0.1 1.7e-54 181.9 0.1 1.5 1 0 0 1 1 1 1 Ankyrin ubiquitin-binding domain OTU PF02338.19 KFQ92027.1 - 3.7e-38 130.9 0.1 9.8e-38 129.5 0.1 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease zf-RanBP PF00641.18 KFQ92027.1 - 1e-10 40.7 30.5 7.4e-06 25.2 6.2 3.7 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others DZR PF12773.7 KFQ92027.1 - 0.024 14.6 13.6 0.7 10.0 7.1 2.8 2 1 0 2 2 2 0 Double zinc ribbon Cluap1 PF10234.9 KFQ92028.1 - 0.0031 16.9 1.8 0.0046 16.4 1.8 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 Pepdidase_M14_N PF18027.1 KFQ92028.1 - 0.081 13.3 0.6 4.8 7.6 0.1 2.4 2 0 0 2 2 2 0 Cytosolic carboxypeptidase N-terminal domain Spore_II_R PF09551.10 KFQ92028.1 - 0.18 12.3 2.4 0.19 12.2 0.9 1.7 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) Methyltransf_31 PF13847.6 KFQ92029.1 - 9.4e-23 80.7 0.0 1.3e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFQ92029.1 - 3.8e-13 50.0 0.0 6.2e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFQ92029.1 - 1.7e-10 41.4 0.0 2.5e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFQ92029.1 - 6.3e-10 39.7 0.0 8.8e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFQ92029.1 - 2.6e-09 37.1 0.0 5.8e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFQ92029.1 - 1.5e-07 31.1 0.0 1.7e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KFQ92029.1 - 1.1e-06 28.3 0.0 1.7e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.11 KFQ92029.1 - 3.4e-05 23.6 0.0 5.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.20 KFQ92029.1 - 0.00019 20.8 0.0 0.00026 20.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 KFQ92029.1 - 0.001 18.7 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 KFQ92029.1 - 0.0021 17.6 0.0 0.0032 17.0 0.0 1.4 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.7 KFQ92029.1 - 0.0025 17.7 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KFQ92029.1 - 0.0027 17.2 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.18 KFQ92029.1 - 0.0028 17.0 0.0 0.0035 16.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KFQ92029.1 - 0.0088 15.8 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 KFQ92029.1 - 0.025 14.6 0.0 0.033 14.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 KFQ92029.1 - 0.03 15.4 0.0 0.04 14.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Pox_MCEL PF03291.16 KFQ92029.1 - 0.035 13.2 0.0 0.1 11.7 0.0 1.8 1 1 0 1 1 1 0 mRNA capping enzyme Cons_hypoth95 PF03602.15 KFQ92029.1 - 0.035 13.8 0.0 0.047 13.3 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 AdoMet_MTase PF07757.13 KFQ92029.1 - 0.062 13.6 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase FAM53 PF15242.6 KFQ92030.1 - 6.3e-101 338.2 28.1 8.6e-101 337.8 28.1 1.2 1 0 0 1 1 1 1 Family of FAM53 Hydrolase_like PF13242.6 KFQ92031.1 - 3.6e-21 75.0 0.0 7e-20 70.9 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KFQ92031.1 - 6.4e-16 58.3 0.0 1e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFQ92031.1 - 1.4e-09 38.3 0.0 1.1e-06 28.8 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFQ92031.1 - 2.5e-07 31.2 0.5 0.00026 21.4 0.1 2.7 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Aminotran_3 PF00202.21 KFQ92032.1 - 1.7e-122 409.0 0.0 2.1e-122 408.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KFQ92032.1 - 0.015 14.5 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Sulfotransfer_1 PF00685.27 KFQ92033.1 - 1.3e-15 57.6 0.0 1.4e-12 47.6 0.0 2.2 2 0 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFQ92033.1 - 6.2e-13 49.6 0.0 2.1e-12 47.9 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase family PVL_ORF50 PF07768.11 KFQ92033.1 - 0.013 15.8 0.1 0.029 14.7 0.1 1.5 1 0 0 1 1 1 0 PVL ORF-50-like family Sulfotransfer_4 PF17784.1 KFQ92033.1 - 0.45 10.3 2.3 3.3 7.5 2.3 2.1 1 1 0 1 1 1 0 Sulfotransferase domain Peptidase_M14 PF00246.24 KFQ92034.1 - 5e-74 249.7 0.1 8e-74 249.0 0.1 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase F5_F8_type_C PF00754.25 KFQ92034.1 - 5.7e-28 97.6 0.1 2.2e-27 95.7 0.1 2.1 2 0 0 2 2 2 1 F5/8 type C domain CarboxypepD_reg PF13620.6 KFQ92034.1 - 1.9e-12 47.2 0.0 4.4e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KFQ92034.1 - 3.7e-05 23.7 0.0 7.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 CarboxypepD_reg-like domain PEGA PF08308.11 KFQ92034.1 - 0.01 15.7 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 0 PEGA domain 7tm_1 PF00001.21 KFQ92036.1 - 4.3e-37 127.9 15.5 5.7e-37 127.5 15.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFQ92036.1 - 7.6e-08 32.3 16.6 7.6e-08 32.3 16.6 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Git3 PF11710.8 KFQ92036.1 - 1.2e-05 25.2 9.9 2e-05 24.5 9.7 1.5 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srbc PF10316.9 KFQ92036.1 - 0.00049 19.7 6.8 0.00049 19.7 6.8 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc TssO PF17561.2 KFQ92036.1 - 0.34 11.0 6.7 0.92 9.6 0.5 2.5 2 0 0 2 2 2 0 Type VI secretion system, TssO WD40 PF00400.32 KFQ92037.1 - 1.5e-22 79.5 2.8 2.4e-05 25.0 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ92037.1 - 7.9e-07 29.3 0.0 1.2 9.5 0.0 4.3 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFQ92037.1 - 0.14 11.1 0.0 0.77 8.6 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Homeodomain PF00046.29 KFQ92038.1 - 3.9e-19 68.2 2.5 5.4e-19 67.8 2.5 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ92038.1 - 0.01 15.7 0.1 0.019 14.9 0.1 1.5 1 0 0 1 1 1 0 Homeobox KN domain Acyl-CoA_dh_1 PF00441.24 KFQ92039.1 - 1.6e-49 168.0 0.4 1.8e-48 164.6 0.2 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFQ92039.1 - 6.2e-28 97.7 0.1 1.3e-27 96.7 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFQ92039.1 - 1.5e-26 92.4 0.0 2.9e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFQ92039.1 - 4.8e-25 88.4 0.0 7.7e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain zf-H2C2_5 PF13909.6 KFQ92040.1 - 8.2e-13 47.8 32.3 2.2e-05 24.1 0.1 4.7 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KFQ92040.1 - 1.3e-12 47.5 45.5 2.6e-07 30.8 4.5 6.3 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ92040.1 - 1.9e-06 28.0 50.2 0.088 13.3 4.4 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ92040.1 - 0.003 18.3 45.3 0.9 10.6 7.4 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger KTI12 PF08433.10 KFQ92041.1 - 3.2e-06 26.8 1.4 5.2e-06 26.1 1.4 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 DUF4259 PF14078.6 KFQ92041.1 - 0.14 12.9 2.5 0.24 12.1 2.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4259) Spc24 PF08286.11 KFQ92041.1 - 4.4 7.6 7.1 0.49 10.6 1.5 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Reprolysin PF01421.19 KFQ92042.1 - 9.3e-56 188.9 0.0 9.3e-56 188.9 0.0 1.9 2 0 0 2 2 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.12 KFQ92042.1 - 5.4e-28 97.7 5.1 5.4e-28 97.7 5.1 4.1 3 2 1 4 4 1 1 ADAM cysteine-rich Pep_M12B_propep PF01562.19 KFQ92042.1 - 8.5e-26 90.9 0.3 1.7e-25 89.9 0.3 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_5 PF13688.6 KFQ92042.1 - 1.4e-21 77.6 0.3 1.4e-21 77.6 0.3 2.4 2 0 0 2 2 2 1 Metallo-peptidase family M12 Disintegrin PF00200.23 KFQ92042.1 - 8.4e-20 71.4 30.3 8.4e-20 71.4 30.3 3.8 3 1 0 3 3 2 1 Disintegrin Reprolysin_3 PF13582.6 KFQ92042.1 - 2.3e-18 66.9 0.6 4.6e-18 65.9 0.6 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFQ92042.1 - 1e-14 54.9 1.4 2.6e-14 53.6 1.4 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFQ92042.1 - 4.9e-11 42.7 0.4 9e-11 41.8 0.4 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFQ92042.1 - 0.00056 19.8 0.1 0.001 18.9 0.1 1.5 1 0 0 1 1 1 1 Matrixin EB PF01683.18 KFQ92042.1 - 0.0018 18.5 12.7 0.0018 18.5 12.7 4.8 3 1 1 4 4 1 1 EB module EGF_2 PF07974.13 KFQ92042.1 - 0.0024 18.2 12.7 0.0024 18.2 12.7 5.8 5 1 1 6 6 5 1 EGF-like domain Peptidase_M57 PF12388.8 KFQ92042.1 - 0.014 15.0 0.9 0.024 14.3 0.9 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Astacin PF01400.24 KFQ92042.1 - 0.023 14.3 0.1 0.048 13.3 0.1 1.5 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M66 PF10462.9 KFQ92042.1 - 0.1 11.5 0.1 0.18 10.8 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 DUF4506 PF14958.6 KFQ92043.1 - 4.1e-24 84.7 0.0 7.2e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4506) ABC_tran PF00005.27 KFQ92043.1 - 5.5 7.5 5.7 21 5.6 0.1 2.9 2 2 0 3 3 3 0 ABC transporter Zona_pellucida PF00100.23 KFQ92044.1 - 2.3e-05 24.3 0.6 2.4e-05 24.3 0.6 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.23 KFQ92045.1 - 1.8e-11 44.3 0.1 1.9e-11 44.3 0.1 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.23 KFQ92046.1 - 7.6e-11 42.3 1.8 8.3e-11 42.2 1.8 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.23 KFQ92047.1 - 1.5e-28 100.3 1.8 1.6e-28 100.2 1.8 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain dNK PF01712.19 KFQ92047.1 - 0.11 12.3 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase Zona_pellucida PF00100.23 KFQ92048.1 - 9.4e-11 42.0 0.1 9.9e-11 41.9 0.1 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.23 KFQ92049.1 - 1.6e-26 93.7 3.1 1.7e-26 93.6 3.1 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.23 KFQ92050.1 - 6e-08 32.8 0.0 6.3e-08 32.7 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.23 KFQ92051.1 - 2.7e-26 92.9 5.0 2.9e-26 92.8 5.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.23 KFQ92052.1 - 1.1e-08 35.2 0.0 1.2e-08 35.1 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Calx-beta PF03160.14 KFQ92053.1 - 3.9e-62 206.7 5.9 2e-35 120.9 0.8 2.6 2 0 0 2 2 2 2 Calx-beta domain Na_Ca_ex PF01699.24 KFQ92053.1 - 1.6e-60 203.4 31.4 1e-33 116.4 11.4 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Na_Ca_ex_C PF16494.5 KFQ92053.1 - 3e-51 173.2 5.8 5.1e-51 172.4 5.8 1.4 1 0 0 1 1 1 1 C-terminal extension of sodium/calcium exchanger domain DnaG_DnaB_bind PF08278.11 KFQ92053.1 - 0.073 13.7 2.0 0.16 12.6 2.0 1.5 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding Pet100 PF09803.9 KFQ92053.1 - 3 8.4 4.5 12 6.5 0.0 2.9 2 1 0 2 2 2 0 Pet100 Sld5 PF05916.11 KFQ92054.1 - 2.8e-05 24.5 0.1 0.00017 22.0 0.0 2.2 3 0 0 3 3 3 1 GINS complex protein CarD_CdnL_TRCF PF02559.16 KFQ92055.1 - 0.044 14.5 1.2 0.089 13.5 1.2 1.8 1 1 0 1 1 1 0 CarD-like/TRCF domain MAD PF05557.13 KFQ92055.1 - 0.14 10.5 30.5 0.16 10.3 30.5 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF4407 PF14362.6 KFQ92055.1 - 0.39 10.0 23.7 0.5 9.7 23.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Dna2 PF08696.11 KFQ92055.1 - 0.56 10.0 5.4 0.73 9.6 5.0 1.5 1 1 0 1 1 1 0 DNA replication factor Dna2 DUF2730 PF10805.8 KFQ92055.1 - 2.3 8.4 12.0 0.11 12.6 3.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) WxL PF13731.6 KFQ92055.1 - 6.1 6.8 7.2 1.6 8.7 0.1 2.1 1 1 1 2 2 2 0 WxL domain surface cell wall-binding DEAD PF00270.29 KFQ92056.1 - 1.2e-42 145.7 0.2 1.8e-42 145.1 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFQ92056.1 - 3.1e-32 111.2 0.0 1.7e-31 108.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFQ92056.1 - 0.00012 22.1 0.0 0.00027 21.0 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KFQ92056.1 - 0.0002 21.8 0.0 0.0022 18.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFQ92056.1 - 0.00022 21.0 0.0 0.00033 20.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain UTP25 PF06862.12 KFQ92056.1 - 0.0047 15.8 0.0 1.1 7.9 0.0 2.1 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 KFQ92056.1 - 0.049 13.9 0.0 0.3 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain ERCC3_RAD25_C PF16203.5 KFQ92056.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Flavi_DEAD PF07652.14 KFQ92056.1 - 0.12 12.4 0.2 0.41 10.6 0.1 2.1 1 1 1 2 2 2 0 Flavivirus DEAD domain Fanconi_A PF03511.14 KFQ92056.1 - 0.19 11.7 0.3 1.5 8.8 0.0 2.3 3 0 0 3 3 3 0 Fanconi anaemia group A protein GBP PF02263.19 KFQ92057.1 - 7.6e-103 343.3 0.0 1e-102 342.9 0.0 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 KFQ92057.1 - 1.9e-06 27.5 0.1 3.9e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain Tiam_CC_Ex PF18385.1 KFQ92057.1 - 0.0052 17.1 0.0 0.021 15.2 0.0 2.0 1 0 0 1 1 1 1 T-lymphoma invasion and metastasis CC-Ex domain ATP-synt_A PF00119.20 KFQ92057.1 - 0.033 14.1 0.1 0.066 13.1 0.1 1.5 1 0 0 1 1 1 0 ATP synthase A chain RRM_5 PF13893.6 KFQ92058.1 - 2e-59 198.7 3.5 4.1e-55 184.7 0.1 3.3 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KFQ92058.1 - 1.8e-17 62.9 1.7 4.9e-07 29.5 0.1 4.6 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KFQ92058.1 - 7.7e-10 38.9 0.1 3.4e-09 36.8 0.0 2.1 3 0 0 3 3 3 1 RRM-like domain RRM_occluded PF16842.5 KFQ92058.1 - 0.00011 21.9 0.0 0.7 9.8 0.0 2.6 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_3 PF08777.11 KFQ92058.1 - 0.0016 18.4 0.0 0.0059 16.6 0.0 1.9 2 0 0 2 2 2 1 RNA binding motif Limkain-b1 PF11608.8 KFQ92058.1 - 0.0074 16.3 0.0 1.2 9.2 0.0 3.1 3 0 0 3 3 3 1 Limkain b1 RL PF17797.1 KFQ92058.1 - 0.02 14.8 0.1 28 4.7 0.0 3.4 3 0 0 3 3 3 0 RL domain DUF4523 PF15023.6 KFQ92058.1 - 0.11 12.3 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Aldose_epim PF01263.20 KFQ92059.1 - 5e-97 324.8 0.0 5.6e-97 324.7 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase RRM_1 PF00076.22 KFQ92060.1 - 8.4e-17 60.8 0.0 1.2e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFQ92060.1 - 0.00058 19.5 0.0 0.0009 18.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KFQ92060.1 - 0.0006 19.8 7.7 0.0012 18.8 7.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KFQ92060.1 - 0.00082 19.3 2.2 0.0019 18.1 2.2 1.7 1 0 0 1 1 1 1 Zinc knuckle Gemin6 PF06372.12 KFQ92062.1 - 1.5e-66 223.1 0.3 1.6e-66 222.9 0.3 1.0 1 0 0 1 1 1 1 Gemin6 protein 53-BP1_Tudor PF09038.10 KFQ92062.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor Ish1 PF10281.9 KFQ92062.1 - 0.049 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein RRM_1 PF00076.22 KFQ92063.1 - 5e-16 58.3 0.0 7e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KFQ92063.1 - 0.00057 19.8 7.7 0.0011 18.9 7.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KFQ92063.1 - 0.0008 19.3 2.3 0.0018 18.2 2.3 1.7 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.6 KFQ92063.1 - 0.0021 17.6 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFQ92063.1 - 0.058 13.3 0.0 0.078 12.8 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif MORN PF02493.20 KFQ92065.1 - 7.2e-11 41.3 0.5 1.3e-09 37.4 0.2 2.0 2 0 0 2 2 2 2 MORN repeat RhoGEF PF00621.20 KFQ92066.1 - 2e-16 60.7 5.2 2.5e-16 60.4 5.2 1.1 1 0 0 1 1 1 1 RhoGEF domain RasGEF PF00617.19 KFQ92068.1 - 2.5e-49 167.9 0.4 5.3e-49 166.8 0.4 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KFQ92068.1 - 1e-31 109.3 0.0 3.4e-31 107.6 0.0 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif RhoGEF PF00621.20 KFQ92068.1 - 2.2e-16 60.6 1.5 5.7e-16 59.3 0.1 2.4 2 0 0 2 2 2 1 RhoGEF domain Histone PF00125.24 KFQ92068.1 - 1.6e-12 47.9 0.0 4.5e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PH PF00169.29 KFQ92068.1 - 5.2e-11 43.0 2.4 5.7e-11 42.9 0.0 2.3 3 0 0 3 3 3 1 PH domain PH_10 PF15411.6 KFQ92068.1 - 0.0013 19.0 0.1 0.0048 17.1 0.1 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 KFQ92068.1 - 0.0017 18.3 0.0 0.007 16.3 0.0 2.0 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 KFQ92068.1 - 0.0023 17.8 0.1 0.0089 15.9 0.1 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain DUF445 PF04286.12 KFQ92068.1 - 0.13 12.0 3.9 7.9 6.2 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF445) CNH PF00780.22 KFQ92069.1 - 4.6e-69 233.1 0.3 7.3e-69 232.4 0.3 1.3 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.25 KFQ92069.1 - 9.2e-57 192.4 0.0 1.3e-56 191.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ92069.1 - 8.8e-37 126.8 0.0 1.4e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFQ92069.1 - 0.0011 17.8 0.0 0.0024 16.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KFQ92069.1 - 0.025 13.9 0.1 0.13 11.5 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Syntaphilin PF15290.6 KFQ92070.1 - 2.9e-73 247.2 21.9 1.7e-71 241.4 19.4 2.2 1 1 1 2 2 2 2 Golgi-localised syntaxin-1-binding clamp FPP PF05911.11 KFQ92070.1 - 0.002 16.4 16.8 0.0029 15.9 16.8 1.2 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil DUF4200 PF13863.6 KFQ92070.1 - 0.04 14.3 22.0 0.84 10.1 5.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Exonuc_VII_L PF02601.15 KFQ92070.1 - 0.049 13.2 6.5 0.072 12.6 6.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit tRNA-synt_2 PF00152.20 KFQ92070.1 - 0.05 12.7 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) DHR10 PF18595.1 KFQ92070.1 - 0.15 12.2 25.5 0.58 10.2 7.8 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain FapA PF03961.13 KFQ92070.1 - 0.22 10.1 9.0 0.36 9.4 9.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A WXG100 PF06013.12 KFQ92070.1 - 0.41 10.9 5.1 0.46 10.7 4.0 1.7 1 1 0 1 1 1 0 Proteins of 100 residues with WXG Phage_HK97_TLTM PF06120.11 KFQ92070.1 - 0.56 9.3 11.1 0.84 8.8 11.1 1.2 1 0 0 1 1 1 0 Tail length tape measure protein CC2-LZ PF16516.5 KFQ92070.1 - 0.59 10.5 18.2 4.3 7.8 4.4 2.6 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Fez1 PF06818.15 KFQ92070.1 - 0.74 10.2 21.0 1.1 9.6 21.0 1.3 1 0 0 1 1 1 0 Fez1 YgaB PF14182.6 KFQ92070.1 - 0.76 10.2 13.7 0.27 11.6 6.8 2.4 1 1 1 2 2 2 0 YgaB-like protein MPS2 PF17060.5 KFQ92070.1 - 1.4 8.1 14.5 2 7.6 3.1 2.1 1 1 1 2 2 2 0 Monopolar spindle protein 2 DUF745 PF05335.13 KFQ92070.1 - 2.1 8.0 12.8 3.9 7.2 12.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) TMF_DNA_bd PF12329.8 KFQ92070.1 - 2.3 8.3 22.0 5.7 7.0 6.9 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.12 KFQ92070.1 - 2.4 8.2 22.8 9.1 6.4 22.8 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 KFQ92070.1 - 2.6 7.1 19.4 4 6.4 5.0 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phlebovirus_NSM PF07246.11 KFQ92070.1 - 2.9 7.2 12.7 4.9 6.4 11.9 1.7 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Prefoldin PF02996.17 KFQ92070.1 - 3.6 7.5 15.8 3.1 7.7 3.4 2.5 2 1 0 2 2 2 0 Prefoldin subunit IBR PF01485.21 KFQ92071.1 - 7.4e-11 42.1 34.6 4.8e-08 33.1 8.5 3.3 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain Cullin_Nedd8 PF10557.9 KFQ92072.1 - 1.3e-12 47.6 0.0 1.7e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Cullin protein neddylation domain Cullin PF00888.22 KFQ92073.1 - 0.00012 20.8 0.0 0.00019 20.2 0.0 1.4 1 1 0 1 1 1 1 Cullin family ANAPC10 PF03256.16 KFQ92073.1 - 0.024 14.3 0.0 0.059 13.0 0.0 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) UQ_con PF00179.26 KFQ92074.1 - 4.5e-48 162.4 0.1 5e-48 162.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFQ92074.1 - 0.011 16.1 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 KFQ92074.1 - 0.021 14.5 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 KFQ92074.1 - 0.054 13.4 0.1 0.086 12.7 0.1 1.4 1 1 0 1 1 1 0 UEV domain TMEM173 PF15009.6 KFQ92075.1 - 1.7e-113 378.7 0.6 2.1e-113 378.3 0.6 1.1 1 0 0 1 1 1 1 Transmembrane protein 173 PRMT5_TIM PF17285.2 KFQ92075.1 - 0.0034 16.6 0.1 0.0082 15.4 0.0 1.6 2 0 0 2 2 2 1 PRMT5 TIM barrel domain Nuc_sug_transp PF04142.15 KFQ92077.1 - 1.7e-42 145.7 20.3 2.1e-42 145.4 20.3 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KFQ92077.1 - 6.6 6.9 41.1 1.2 9.3 12.3 2.3 2 0 0 2 2 2 0 EamA-like transporter family LRR_4 PF12799.7 KFQ92078.1 - 5.1e-16 58.5 13.1 0.0074 16.7 0.0 5.6 3 1 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFQ92078.1 - 3.8e-14 52.2 12.8 0.00012 21.8 3.6 5.2 2 2 3 5 5 5 5 Leucine rich repeat LRR_1 PF00560.33 KFQ92078.1 - 0.00015 21.9 12.4 3.8 8.4 0.0 7.7 7 2 0 7 7 7 1 Leucine Rich Repeat LRRCT PF01463.24 KFQ92078.1 - 0.0031 17.9 0.2 0.02 15.4 0.2 2.5 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain LRR_6 PF13516.6 KFQ92078.1 - 0.0052 16.7 12.2 9.4 6.6 0.0 6.2 6 1 0 6 6 6 2 Leucine Rich repeat Arm PF00514.23 KFQ92079.1 - 0.00045 20.2 22.5 0.96 9.6 0.1 7.7 6 1 1 7 7 7 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 KFQ92079.1 - 0.18 11.8 3.3 15 5.7 0.6 3.4 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 KFQ92079.1 - 0.77 10.3 15.2 1.6 9.3 0.0 5.0 3 2 1 4 4 4 0 HEAT-like repeat L51_S25_CI-B8 PF05047.16 KFQ92080.1 - 3.5e-17 62.1 0.0 4.3e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RED_N PF07808.13 KFQ92081.1 - 1.9e-100 335.3 16.2 1.9e-100 335.3 16.2 2.6 2 0 0 2 2 2 1 RED-like protein N-terminal region RED_C PF07807.11 KFQ92081.1 - 3.5e-49 166.0 6.3 3.5e-49 166.0 6.3 3.8 4 1 0 4 4 4 1 RED-like protein C-terminal region Lsm_interact PF05391.11 KFQ92081.1 - 0.012 15.1 0.1 0.045 13.3 0.1 2.1 1 0 0 1 1 1 0 Lsm interaction motif MCR_C PF04609.12 KFQ92081.1 - 1.1 8.3 3.2 0.31 10.1 0.1 1.7 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein C WD40 PF00400.32 KFQ92082.1 - 2.8e-16 59.6 4.7 0.0043 17.9 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ92082.1 - 2.6e-09 37.2 0.2 0.098 13.0 0.0 3.9 2 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFQ92082.1 - 0.0002 20.8 0.0 0.21 10.9 0.0 2.6 2 1 1 3 3 3 2 WD40-like domain PQQ_3 PF13570.6 KFQ92082.1 - 0.00022 21.6 0.1 4 8.0 0.0 4.7 5 0 0 5 5 5 1 PQQ-like domain BBS2_Mid PF14783.6 KFQ92082.1 - 0.013 15.5 0.0 0.25 11.4 0.0 2.4 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.11 KFQ92082.1 - 0.026 13.3 0.0 3.7 6.2 0.0 2.2 1 1 1 2 2 2 0 Nup133 N terminal like Antimicrobial22 PF16047.5 KFQ92082.1 - 0.065 13.1 0.3 0.16 11.8 0.3 1.7 1 0 0 1 1 1 0 Frog antimicrobial peptide Ge1_WD40 PF16529.5 KFQ92082.1 - 0.19 10.6 0.0 18 4.2 0.0 2.9 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein tRNA-synt_His PF13393.6 KFQ92083.1 - 4.8e-41 141.0 0.0 8.1e-41 140.3 0.0 1.3 2 0 0 2 2 2 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KFQ92083.1 - 9.1e-17 61.0 1.2 1.8e-16 60.0 1.2 1.5 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 KFQ92083.1 - 5.1e-09 36.0 0.5 7.2e-09 35.5 0.5 1.2 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 KFQ92083.1 - 0.0012 18.0 0.0 0.0033 16.6 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) FAM198 PF15051.6 KFQ92083.1 - 0.12 11.2 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 FAM198 protein WHEP-TRS PF00458.20 KFQ92083.1 - 0.39 10.9 2.4 0.45 10.7 0.4 2.2 2 0 0 2 2 2 0 WHEP-TRS domain tRNA-synt_His PF13393.6 KFQ92084.1 - 1e-31 110.4 0.0 1.5e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KFQ92084.1 - 1.5e-14 53.9 0.0 3.1e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 KFQ92084.1 - 0.0002 21.0 0.0 0.00026 20.6 0.0 1.2 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2b PF00587.25 KFQ92084.1 - 0.0019 18.2 0.0 0.0056 16.7 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) FAM198 PF15051.6 KFQ92084.1 - 0.16 10.8 0.1 0.46 9.3 0.0 1.7 2 0 0 2 2 2 0 FAM198 protein zf-C2H2_jaz PF12171.8 KFQ92085.1 - 8e-07 29.2 1.5 8e-07 29.2 1.5 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFQ92085.1 - 1.6e-06 28.3 1.4 2.5e-06 27.7 1.4 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SNRNP27 PF08648.12 KFQ92085.1 - 9.7e-05 22.4 0.3 9.7e-05 22.4 0.3 2.5 4 0 0 4 4 4 1 U4/U6.U5 small nuclear ribonucleoproteins zf-U1 PF06220.12 KFQ92085.1 - 0.00015 21.4 1.0 0.00026 20.7 1.0 1.4 1 0 0 1 1 1 1 U1 zinc finger Cgr1 PF03879.14 KFQ92085.1 - 0.014 15.7 16.8 0.014 15.7 16.8 2.1 2 0 0 2 2 2 0 Cgr1 family DUF4250 PF14056.6 KFQ92085.1 - 0.046 13.7 0.4 0.13 12.3 0.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4250) zf-C2H2 PF00096.26 KFQ92085.1 - 0.75 10.4 3.9 0.26 11.8 1.0 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type Vma12 PF11712.8 KFQ92085.1 - 2.7 8.1 8.1 19 5.3 5.2 2.1 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Presenilin PF01080.17 KFQ92085.1 - 3.4 6.3 3.6 3.2 6.4 3.6 1.2 1 0 0 1 1 1 0 Presenilin Vfa1 PF08432.10 KFQ92085.1 - 8.3 6.7 23.5 0.17 12.2 14.6 1.9 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Meis_PKNOX_N PF16493.5 KFQ92086.1 - 1.9e-39 133.9 1.4 3e-39 133.2 1.4 1.3 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 Homeobox_KN PF05920.11 KFQ92086.1 - 1.1e-19 70.1 2.3 2.1e-19 69.1 2.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFQ92086.1 - 5.6e-08 32.5 0.5 1.3e-07 31.4 0.5 1.6 1 0 0 1 1 1 1 Homeodomain Na_trans_assoc PF06512.13 KFQ92086.1 - 0.025 14.9 0.7 0.052 13.8 0.7 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated RNA_pol_3_Rpc31 PF11705.8 KFQ92086.1 - 0.035 14.4 6.7 0.06 13.6 6.7 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Myc_N PF01056.18 KFQ92086.1 - 0.08 12.8 1.8 0.12 12.2 1.8 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Med4 PF10018.9 KFQ92086.1 - 0.12 12.0 6.2 0.48 10.1 0.0 2.3 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Voldacs PF03517.13 KFQ92086.1 - 0.22 11.6 5.3 0.39 10.8 5.3 1.4 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling NOA36 PF06524.12 KFQ92086.1 - 0.73 9.1 10.9 0.061 12.6 6.3 1.5 2 0 0 2 2 2 0 NOA36 protein TT_ORF2 PF02957.15 KFQ92086.1 - 0.81 10.6 5.4 1.9 9.4 5.4 1.7 1 0 0 1 1 1 0 TT viral ORF2 DNA_pol_phi PF04931.13 KFQ92086.1 - 0.92 7.5 10.8 1.7 6.7 10.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 KFQ92086.1 - 1.5 7.9 5.6 2.9 7.0 5.6 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4746 PF15928.5 KFQ92086.1 - 6.9 6.0 8.5 12 5.2 8.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) V-set PF07686.17 KFQ92087.1 - 9.8e-08 32.1 0.0 1.1e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFQ92087.1 - 0.11 13.1 0.0 0.12 13.0 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KFQ92088.1 - 1.1e-06 28.8 0.0 1.3e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain V-set PF07686.17 KFQ92089.1 - 2.1e-10 40.7 0.0 2.3e-10 40.6 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Phytoreo_P8 PF07124.11 KFQ92089.1 - 0.083 11.8 0.1 0.086 11.8 0.1 1.0 1 0 0 1 1 1 0 Phytoreovirus outer capsid protein P8 Pkinase PF00069.25 KFQ92090.1 - 8.7e-74 248.2 0.2 2.8e-73 246.5 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ92090.1 - 1.3e-33 116.4 0.0 3.3e-33 115.1 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFQ92090.1 - 2.7e-07 29.9 0.1 2.7e-07 29.9 0.1 2.6 3 0 0 3 3 3 1 Haspin like kinase domain Kinase-like PF14531.6 KFQ92090.1 - 0.00031 20.2 0.0 0.0027 17.1 0.0 2.1 1 1 0 1 1 1 1 Kinase-like Med1 PF10744.9 KFQ92091.1 - 2.1e-64 218.1 0.0 1e-63 215.9 0.0 2.3 2 0 0 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 LRR_4 PF12799.7 KFQ92092.1 - 1.4e-19 69.9 11.6 0.0084 16.5 0.2 6.4 6 0 0 6 6 6 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFQ92092.1 - 1.2e-18 65.5 24.7 0.0031 17.4 0.1 10.1 11 0 0 11 11 11 6 Leucine Rich repeat F-box-like PF12937.7 KFQ92092.1 - 2.8e-13 49.5 0.6 1.1e-12 47.6 0.6 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFQ92092.1 - 1.5e-07 31.1 0.7 1.5e-07 31.1 0.7 2.5 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.6 KFQ92092.1 - 8.7e-06 25.4 5.4 0.032 14.0 0.3 5.3 3 2 3 6 6 6 2 Leucine rich repeat LRR_1 PF00560.33 KFQ92092.1 - 0.00024 21.2 23.5 14 6.7 0.1 10.0 11 1 0 11 11 11 2 Leucine Rich Repeat F-box_4 PF15966.5 KFQ92092.1 - 0.0076 16.1 2.6 0.012 15.5 0.0 2.7 3 0 0 3 3 3 1 F-box Ribosomal_L19e PF01280.20 KFQ92093.1 - 1e-65 220.2 12.9 1e-65 220.2 12.9 2.0 1 1 1 2 2 2 1 Ribosomal protein L19e DUF1682 PF07946.14 KFQ92093.1 - 4.6 6.4 15.4 5.8 6.0 15.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Guanylate_kin PF00625.21 KFQ92094.1 - 1.3e-36 126.0 1.2 2.2e-36 125.3 0.3 1.7 2 0 0 2 2 2 1 Guanylate kinase VGCC_beta4Aa_N PF12052.8 KFQ92094.1 - 7.3e-23 80.4 5.8 1.4e-22 79.5 5.8 1.5 1 0 0 1 1 1 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal SH3_1 PF00018.28 KFQ92094.1 - 0.001 18.6 0.0 0.0053 16.3 0.0 2.1 2 0 0 2 2 2 1 SH3 domain DUF4064 PF13273.6 KFQ92095.1 - 0.018 15.3 0.9 0.038 14.3 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) SH3_9 PF14604.6 KFQ92096.1 - 1.3e-15 56.9 0.2 2.1e-15 56.3 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFQ92096.1 - 3.7e-13 48.9 0.1 6.1e-13 48.2 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFQ92096.1 - 4.5e-08 32.7 0.0 1.2e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain LIM PF00412.22 KFQ92096.1 - 3.6e-07 30.3 7.4 5.7e-07 29.7 7.4 1.3 1 0 0 1 1 1 1 LIM domain Nebulin PF00880.18 KFQ92096.1 - 3.7e-05 23.5 0.3 0.055 13.4 0.2 2.7 2 0 0 2 2 2 2 Nebulin repeat Ribosomal_L14 PF00238.19 KFQ92097.1 - 3.7e-36 123.9 0.2 4.3e-36 123.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Big_2 PF02368.18 KFQ92098.1 - 7.5e-15 54.6 1.2 8.9e-13 48.0 0.0 6.8 9 0 0 9 9 9 2 Bacterial Ig-like domain (group 2) AlphaC_N PF08829.10 KFQ92098.1 - 0.11 12.5 0.0 3.2 7.8 0.0 3.0 2 0 0 2 2 2 0 Alpha C protein N terminal PQQ PF01011.21 KFQ92098.1 - 0.15 12.1 0.1 0.48 10.4 0.1 1.8 1 0 0 1 1 1 0 PQQ enzyme repeat T2SS-T3SS_pil_N PF13629.6 KFQ92098.1 - 0.68 9.7 15.7 6.1 6.6 0.0 6.6 7 0 0 7 7 7 0 Pilus formation protein N terminal region Hist_deacetyl PF00850.19 KFQ92099.1 - 6.5e-52 176.9 0.0 8.7e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain wnt PF00110.19 KFQ92100.1 - 7.3e-125 416.6 23.7 1.1e-124 416.1 23.7 1.2 1 0 0 1 1 1 1 wnt family COG6 PF06419.11 KFQ92100.1 - 0.26 9.5 0.1 0.36 9.0 0.1 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 DSPc PF00782.20 KFQ92101.1 - 3.4e-12 46.3 0.0 9.5e-12 44.9 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFQ92101.1 - 3.2e-08 33.4 0.0 6.1e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KFQ92101.1 - 0.00044 20.0 0.0 0.0012 18.5 0.0 1.7 1 1 1 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 KFQ92101.1 - 0.0036 17.3 0.0 0.0092 16.0 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family BDV_P24 PF06595.11 KFQ92101.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Borna disease virus P24 protein 23S_rRNA_IVP PF05635.11 KFQ92101.1 - 0.084 13.2 0.1 0.78 10.1 0.0 2.6 2 0 0 2 2 2 0 23S rRNA-intervening sequence protein Pkinase PF00069.25 KFQ92105.1 - 5.1e-47 160.5 0.0 9.2e-47 159.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ92105.1 - 1.8e-36 125.7 0.0 3.3e-36 124.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 KFQ92105.1 - 4.9e-31 106.7 3.1 9.9e-26 89.7 0.2 2.6 2 0 0 2 2 2 2 Oxidative-stress-responsive kinase 1 C-terminal domain DUF3447 PF11929.8 KFQ92105.1 - 0.053 13.5 0.1 0.053 13.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) Ninjurin PF04923.12 KFQ92106.1 - 4.2e-37 126.2 5.5 4.9e-37 126.0 5.5 1.0 1 0 0 1 1 1 1 Ninjurin CARD PF00619.21 KFQ92107.1 - 5.8e-07 29.5 0.4 1.1e-06 28.6 0.3 1.6 1 1 0 1 1 1 1 Caspase recruitment domain Cytokin_check_N PF10407.9 KFQ92107.1 - 0.0048 16.8 2.1 2.1 8.3 0.6 2.4 2 1 0 2 2 2 2 Cdc14 phosphatase binding protein N-terminus DUF2732 PF10809.8 KFQ92107.1 - 0.04 13.8 0.1 0.073 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) DUF1640 PF07798.11 KFQ92107.1 - 0.041 13.9 1.2 0.053 13.6 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Sushi PF00084.20 KFQ92108.1 - 4.1e-06 27.3 0.2 6.4e-06 26.7 0.2 1.3 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) DUF728 PF05304.12 KFQ92108.1 - 0.0061 16.4 0.3 0.0089 15.9 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF728) Shisa PF13908.6 KFQ92108.1 - 0.037 14.3 0.3 0.041 14.1 0.3 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RhoGEF PF00621.20 KFQ92110.1 - 1.8e-47 162.0 3.8 2.9e-47 161.3 0.6 2.3 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 KFQ92110.1 - 2.4e-22 79.4 0.2 3.1e-13 50.1 0.0 2.7 2 0 0 2 2 2 2 PH domain FYVE PF01363.21 KFQ92110.1 - 1.6e-14 53.7 14.1 3.1e-13 49.6 14.8 2.5 2 0 0 2 2 2 1 FYVE zinc finger PH_13 PF16652.5 KFQ92110.1 - 0.00015 21.6 1.5 0.073 12.9 2.1 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 KFQ92110.1 - 0.00032 20.7 1.4 0.00048 20.1 0.5 1.7 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KFQ92110.1 - 0.016 15.6 0.4 1.9 8.9 0.1 2.9 2 1 0 2 2 2 0 Pleckstrin homology domain PH_9 PF15410.6 KFQ92110.1 - 0.031 14.7 2.1 5.4 7.4 0.1 3.1 3 0 0 3 3 3 0 Pleckstrin homology domain PH_16 PF17838.1 KFQ92110.1 - 0.049 13.5 1.6 0.16 11.8 0.1 2.3 2 0 0 2 2 2 0 PH domain FYVE_2 PF02318.16 KFQ92110.1 - 0.93 9.7 23.0 0.043 14.0 13.0 3.1 3 0 0 3 3 3 0 FYVE-type zinc finger FYDLN_acid PF09538.10 KFQ92110.1 - 5.1 7.8 14.7 9.7 6.9 2.7 3.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DZR PF12773.7 KFQ92110.1 - 5.4 7.1 15.2 29 4.8 2.0 2.7 1 1 1 2 2 2 0 Double zinc ribbon MHC_I_3 PF16497.5 KFQ92111.1 - 3.8e-21 75.5 2.8 4.5e-21 75.2 2.8 1.1 1 0 0 1 1 1 1 MHC-I family domain MHC_I PF00129.18 KFQ92111.1 - 1.5e-11 44.2 0.2 1.8e-11 43.9 0.2 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.15 KFQ92111.1 - 4.7e-06 26.9 0.0 1.7e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Ig_2 PF13895.6 KFQ92111.1 - 0.08 13.3 0.0 0.34 11.3 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin domain MHC_I_3 PF16497.5 KFQ92112.1 - 3e-26 92.1 0.1 3.8e-26 91.8 0.1 1.1 1 0 0 1 1 1 1 MHC-I family domain C1-set PF07654.15 KFQ92112.1 - 7.9e-18 64.6 0.0 1.5e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I PF00129.18 KFQ92112.1 - 1.7e-06 27.7 0.0 2.4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 Ig_2 PF13895.6 KFQ92112.1 - 2.3e-05 24.6 0.0 5.1e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFQ92112.1 - 0.00049 20.6 0.0 0.00094 19.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 KFQ92112.1 - 0.001 19.1 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain I-set PF07679.16 KFQ92112.1 - 0.0066 16.5 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 KFQ92113.1 - 8.2e-08 32.4 0.0 8.2e-08 32.4 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain LRR_6 PF13516.6 KFQ92114.1 - 3.1e-09 36.1 8.5 3.1 8.1 0.0 8.6 9 0 0 9 9 9 2 Leucine Rich repeat F-box-like PF12937.7 KFQ92114.1 - 1.2e-06 28.2 2.9 1.2e-06 28.2 2.9 1.9 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KFQ92114.1 - 1.7e-06 28.3 7.4 0.58 10.7 2.5 5.8 3 2 5 8 8 8 3 Leucine Rich repeats (2 copies) F-box PF00646.33 KFQ92114.1 - 0.0026 17.6 2.3 0.0026 17.6 2.3 2.8 3 1 1 4 4 4 1 F-box domain DUF3885 PF13021.6 KFQ92114.1 - 0.096 12.8 0.0 8.4 6.6 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) Pkinase_Tyr PF07714.17 KFQ92115.1 - 6.5e-102 340.2 0.2 2.3e-101 338.4 0.0 2.1 2 1 1 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ92115.1 - 2.4e-50 171.4 0.0 9.6e-50 169.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain SH2 PF00017.24 KFQ92115.1 - 1.1e-21 76.7 0.0 4e-21 74.9 0.0 2.0 1 0 0 1 1 1 1 SH2 domain FCH PF00611.23 KFQ92115.1 - 1.2e-11 44.7 2.6 1.2e-11 44.7 2.6 3.3 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain ABC1 PF03109.16 KFQ92115.1 - 0.49 10.6 5.2 1.2 9.3 0.0 4.0 4 0 0 4 4 4 0 ABC1 family zf-RING_2 PF13639.6 KFQ92116.1 - 1.8e-05 25.0 9.6 1.8e-05 25.0 9.6 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KFQ92116.1 - 0.00013 21.6 10.3 0.00032 20.4 10.3 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KFQ92116.1 - 0.00041 20.2 6.4 0.0012 18.7 6.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFQ92116.1 - 0.005 16.8 5.9 0.005 16.8 5.9 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Amidase PF01425.21 KFQ92116.1 - 0.038 12.9 0.0 0.059 12.3 0.0 1.2 1 0 0 1 1 1 0 Amidase zf-rbx1 PF12678.7 KFQ92116.1 - 0.086 13.1 7.1 0.24 11.7 7.1 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFQ92116.1 - 0.3 11.2 3.8 0.58 10.3 3.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KFQ92116.1 - 0.34 10.8 12.0 0.11 12.4 8.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFQ92116.1 - 0.43 10.6 8.8 1.1 9.2 8.8 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Glyco_hydro_38N PF01074.22 KFQ92117.1 - 1.4e-108 362.6 4.9 2.4e-108 361.9 4.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KFQ92117.1 - 1e-40 140.1 0.1 2.5e-40 138.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KFQ92117.1 - 1e-25 89.7 0.0 2.1e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase middle domain WAC_Acf1_DNA_bd PF10537.9 KFQ92117.1 - 0.005 17.3 0.4 0.014 15.9 0.4 1.8 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal Mito_carr PF00153.27 KFQ92118.1 - 6e-20 71.0 0.1 2e-11 43.6 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein Utp21 PF04192.12 KFQ92119.1 - 2e-66 223.8 0.1 3.2e-66 223.2 0.1 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 KFQ92119.1 - 2.2e-21 75.8 10.9 1.6e-09 38.2 0.6 8.7 10 0 0 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ92119.1 - 9e-11 41.9 0.1 0.003 17.8 0.0 6.7 4 3 4 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KFQ92119.1 - 0.0012 19.1 0.9 0.0027 18.0 0.9 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 KFQ92119.1 - 0.098 11.6 0.0 0.74 8.7 0.0 2.4 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SGL PF08450.12 KFQ92119.1 - 0.14 11.7 0.0 0.57 9.7 0.0 1.9 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Pkinase PF00069.25 KFQ92120.1 - 1.7e-46 158.7 0.0 1.9e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ92120.1 - 2.5e-15 56.5 0.0 2.8e-15 56.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ92120.1 - 0.00028 20.3 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like START PF01852.19 KFQ92121.1 - 7.8e-18 64.6 0.0 8.4e-18 64.5 0.0 1.0 1 0 0 1 1 1 1 START domain Alveol-reg_P311 PF11092.8 KFQ92122.1 - 1.7e-35 120.9 0.1 1.9e-35 120.8 0.1 1.0 1 0 0 1 1 1 1 Neuronal protein 3.1 (p311) Parecho_VpG PF06344.11 KFQ92122.1 - 0.11 13.1 0.8 43 5.1 0.4 3.1 2 1 0 2 2 2 0 Parechovirus Genome-linked protein Arm_APC_u3 PF16629.5 KFQ92123.1 - 2.2e-174 579.0 21.0 2.2e-174 579.0 21.0 4.0 5 0 0 5 5 3 1 Armadillo-associated region on APC APC_basic PF05956.11 KFQ92123.1 - 7.4e-101 338.0 74.8 7.4e-101 338.0 74.8 8.9 11 1 0 11 11 4 1 APC basic domain EB1_binding PF05937.11 KFQ92123.1 - 3.1e-93 311.2 22.1 3.1e-93 311.2 22.1 8.2 7 2 2 9 9 2 1 EB-1 Binding Domain APC_r PF05923.12 KFQ92123.1 - 7.3e-72 235.9 45.2 1.6e-11 43.6 1.7 8.9 8 0 0 8 8 8 7 APC repeat APC_u5 PF16630.5 KFQ92123.1 - 1e-53 180.5 7.6 1e-53 180.5 7.6 5.3 4 1 1 5 5 1 1 Unstructured region on APC between 1st and 2nd catenin-bdg motifs APC_u9 PF16633.5 KFQ92123.1 - 8.4e-43 145.4 10.6 8.4e-43 145.4 10.6 5.2 2 0 0 2 2 2 1 Unstructured region on APC between 1st two creatine-rich regions APC_u14 PF16635.5 KFQ92123.1 - 1e-40 138.1 11.1 1e-40 138.1 11.1 5.2 6 0 0 6 6 2 1 Unstructured region on APC between SAMP and APC_crr APC_rep PF18797.1 KFQ92123.1 - 9.6e-38 129.0 0.9 9.6e-38 129.0 0.9 4.5 5 0 0 5 5 2 1 Adenomatous polyposis coli (APC) repeat APC_u15 PF16636.5 KFQ92123.1 - 4.5e-32 110.3 6.8 4.5e-32 110.3 6.8 8.3 10 1 0 10 10 4 1 Unstructured region on APC between APC_crr regions 5 and 6 APC_N_CC PF16689.5 KFQ92123.1 - 1.7e-28 98.4 7.3 1.7e-28 98.4 7.3 4.2 5 0 0 5 5 4 1 Coiled-coil N-terminus of APC, dimerisation domain Arm PF00514.23 KFQ92123.1 - 9.6e-25 85.8 12.9 8.7e-07 28.8 0.4 6.8 6 0 0 6 6 6 5 Armadillo/beta-catenin-like repeat APC_u13 PF16634.5 KFQ92123.1 - 1.1e-23 82.9 2.8 1.1e-23 82.9 2.8 2.9 2 0 0 2 2 2 1 Unstructured region on APC between APC_crr and SAMP APC_15aa PF05972.11 KFQ92123.1 - 1e-22 78.9 27.9 4.9e-06 26.5 0.3 5.8 6 0 0 6 6 5 4 APC 15 residue motif Suppressor_APC PF11414.8 KFQ92123.1 - 1.9e-21 75.9 4.5 1.9e-21 75.9 4.5 3.6 3 0 0 3 3 3 1 Adenomatous polyposis coli tumour suppressor protein SAMP PF05924.11 KFQ92123.1 - 1.5e-16 59.0 14.6 8.1e-08 31.3 2.3 4.0 3 0 0 3 3 3 2 SAMP Motif Sec7_N PF12783.7 KFQ92123.1 - 0.17 11.8 0.1 0.41 10.5 0.1 1.6 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal bZIP_1 PF00170.21 KFQ92123.1 - 0.17 12.0 3.2 1.4 9.1 3.2 2.7 1 0 0 1 1 1 0 bZIP transcription factor DUF3361 PF11841.8 KFQ92123.1 - 2.6 7.9 4.1 8.5 6.3 0.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3361) JIP_LZII PF16471.5 KFQ92123.1 - 3.9 7.7 16.6 0.066 13.4 3.3 3.5 3 0 0 3 3 2 0 JNK-interacting protein leucine zipper II SRP19 PF01922.17 KFQ92124.1 - 7.3e-26 91.0 0.0 9.1e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 SRP19 protein TB2_DP1_HVA22 PF03134.19 KFQ92125.1 - 6.2e-30 103.0 2.0 7.2e-30 102.8 2.0 1.1 1 0 0 1 1 1 1 TB2/DP1, HVA22 family UNC-79 PF14776.6 KFQ92126.1 - 3.2e-06 26.2 0.1 6.6e-06 25.2 0.1 1.5 1 1 1 2 2 2 1 Cation-channel complex subunit UNC-79 BTB PF00651.31 KFQ92127.1 - 2.8e-25 88.7 0.2 5.5e-14 52.3 0.0 3.5 1 1 0 2 2 2 2 BTB/POZ domain BACK PF07707.15 KFQ92127.1 - 1.5e-10 41.1 0.2 4e-10 39.7 0.2 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch PHD PF00628.29 KFQ92128.1 - 0.0039 17.1 5.4 0.0039 17.1 5.4 3.6 2 1 0 2 2 2 1 PHD-finger DUF3408 PF11888.8 KFQ92128.1 - 0.99 9.5 9.2 0.42 10.7 4.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3408) TMEM251 PF15190.6 KFQ92129.1 - 5.7e-70 233.2 2.5 6.5e-70 233.1 2.5 1.0 1 0 0 1 1 1 1 Transmembrane protein 251 DUF4064 PF13273.6 KFQ92129.1 - 0.0017 18.6 0.0 0.0025 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) AA_permease PF00324.21 KFQ92129.1 - 0.013 14.1 0.2 0.017 13.7 0.2 1.2 1 0 0 1 1 1 0 Amino acid permease TctB PF07331.11 KFQ92129.1 - 0.092 13.0 2.2 0.62 10.3 2.6 1.8 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF4131 PF13567.6 KFQ92129.1 - 0.1 12.2 3.2 1.2 8.7 2.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Ins134_P3_kin PF05770.11 KFQ92130.1 - 2.2e-83 278.7 0.1 3.3e-83 278.1 0.1 1.2 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 KFQ92130.1 - 1.1e-18 67.3 1.4 5.9e-18 65.0 0.6 2.4 2 0 0 2 2 2 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain RimK PF08443.11 KFQ92130.1 - 0.0003 20.5 0.1 0.58 9.7 0.0 2.6 3 0 0 3 3 3 2 RimK-like ATP-grasp domain Golgin_A5 PF09787.9 KFQ92132.1 - 7.9e-139 462.3 28.4 7.9e-139 462.3 28.4 3.5 2 1 2 4 4 4 2 Golgin subfamily A member 5 Spc7 PF08317.11 KFQ92132.1 - 0.00023 20.2 91.8 0.0075 15.2 11.0 5.0 2 1 3 5 5 5 3 Spc7 kinetochore protein ATG16 PF08614.11 KFQ92132.1 - 0.0039 17.5 17.6 0.0039 17.5 17.6 5.4 2 1 3 5 5 5 2 Autophagy protein 16 (ATG16) HOOK PF05622.12 KFQ92132.1 - 0.0063 14.7 84.6 0.073 11.2 30.1 2.4 1 1 1 2 2 2 2 HOOK protein PKcGMP_CC PF16808.5 KFQ92132.1 - 0.013 15.3 1.0 0.013 15.3 1.0 4.7 6 0 0 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TPR_MLP1_2 PF07926.12 KFQ92132.1 - 0.95 9.5 105.4 0.15 12.1 31.8 6.3 3 2 2 5 5 5 0 TPR/MLP1/MLP2-like protein Peptidase_C13 PF01650.18 KFQ92133.1 - 1.1e-116 388.9 2.0 1.8e-116 388.1 2.0 1.3 1 0 0 1 1 1 1 Peptidase C13 family DUF2675 PF11247.8 KFQ92133.1 - 0.081 13.1 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2675) VPS9 PF02204.18 KFQ92134.1 - 9.9e-27 93.2 0.1 9.9e-27 93.2 0.1 1.8 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain RA PF00788.23 KFQ92134.1 - 5.5e-06 26.9 0.6 1.5e-05 25.5 0.0 2.0 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain SH2 PF00017.24 KFQ92134.1 - 0.15 12.2 0.0 0.7 10.0 0.0 2.3 2 0 0 2 2 2 0 SH2 domain Lactamase_B_6 PF16661.5 KFQ92135.1 - 1.8e-63 213.5 0.0 4.5e-63 212.2 0.0 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KFQ92135.1 - 1.2e-42 145.9 1.6 7.8e-42 143.3 0.0 2.2 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KFQ92135.1 - 1.6e-20 73.5 0.0 3.3e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 KFQ92135.1 - 2.8e-15 56.0 0.0 5.8e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 KFQ92135.1 - 2.1e-06 27.9 0.0 4.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFQ92135.1 - 8.8e-05 22.1 0.0 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 KFQ92135.1 - 0.0018 17.6 0.1 0.018 14.3 0.0 2.4 2 1 0 2 2 2 1 Putative beta-lactamase-like family NADH_oxidored PF08040.11 KFQ92136.1 - 6.7e-36 121.8 0.1 7.3e-36 121.7 0.1 1.0 1 0 0 1 1 1 1 MNLL subunit Josephin PF02099.17 KFQ92137.1 - 1.3e-53 181.5 1.3 1.5e-53 181.3 0.0 1.7 2 0 0 2 2 2 1 Josephin SUIM_assoc PF16619.5 KFQ92137.1 - 7.8e-18 64.3 8.8 2.2e-17 62.9 8.8 1.8 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 UIM PF02809.20 KFQ92137.1 - 3.3e-11 42.3 27.3 5e-05 22.9 0.8 4.9 4 0 0 4 4 4 3 Ubiquitin interaction motif TolA_bind_tri PF16331.5 KFQ92138.1 - 0.00072 19.6 2.0 0.00072 19.6 2.0 21.5 11 6 9 21 21 21 2 TolA binding protein trimerisation DUF4407 PF14362.6 KFQ92138.1 - 0.0023 17.3 11.8 0.0023 17.3 11.8 12.3 1 1 8 9 9 9 1 Domain of unknown function (DUF4407) AP_endonuc_2 PF01261.24 KFQ92138.1 - 6 6.2 6.5 5 6.5 0.2 3.7 3 0 0 3 3 3 0 Xylose isomerase-like TIM barrel EGF_CA PF07645.15 KFQ92139.1 - 7.2e-46 154.1 89.5 2.6e-11 43.5 8.3 7.4 8 0 0 8 8 8 6 Calcium-binding EGF domain cEGF PF12662.7 KFQ92139.1 - 2e-35 120.3 54.6 5.3e-12 45.4 3.8 7.6 8 0 0 8 8 8 6 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFQ92139.1 - 1e-24 86.5 94.0 6.7e-08 32.7 9.7 8.9 8 1 0 8 8 8 4 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 KFQ92139.1 - 3.5e-12 46.3 68.0 1.1e-06 28.7 4.2 7.9 7 1 1 8 8 8 5 EGF domain hEGF PF12661.7 KFQ92139.1 - 1.6e-06 28.5 73.8 0.013 16.1 5.1 8.8 7 1 0 7 7 7 4 Human growth factor-like EGF EGF PF00008.27 KFQ92139.1 - 1e-05 25.7 88.7 0.00026 21.2 8.3 7.9 8 0 0 8 8 8 4 EGF-like domain RANK_CRD_2 PF18278.1 KFQ92139.1 - 6.8 6.9 22.4 2.9 8.1 0.2 6.1 6 0 0 6 6 6 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 C2 PF00168.30 KFQ92140.1 - 1.5e-16 60.6 0.1 1.3e-09 38.3 0.1 2.2 2 0 0 2 2 2 2 C2 domain SMK-1 PF04802.15 KFQ92141.1 - 2.7e-80 268.7 9.6 2.8e-80 268.7 7.1 2.2 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 WH1 PF00568.23 KFQ92141.1 - 0.00038 20.4 0.0 0.00086 19.2 0.0 1.6 1 0 0 1 1 1 1 WH1 domain Ran_BP1 PF00638.18 KFQ92141.1 - 0.0066 16.7 0.0 0.023 14.9 0.0 2.0 1 0 0 1 1 1 1 RanBP1 domain Collagen PF01391.18 KFQ92141.1 - 0.028 14.2 1.8 0.047 13.4 1.8 1.2 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) DUF4392 PF14336.6 KFQ92142.1 - 6.1e-117 390.3 0.0 7.9e-117 389.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) DUF1445 PF07286.12 KFQ92142.1 - 6.5e-64 214.2 0.0 1e-63 213.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Pkinase PF00069.25 KFQ92143.1 - 1.6e-141 470.3 0.4 3.6e-72 242.9 0.2 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ92143.1 - 3.7e-67 226.3 0.1 2.1e-33 115.7 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KFQ92143.1 - 4.9e-13 48.9 1.3 2.1e-09 37.1 0.2 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFQ92143.1 - 9.1e-13 48.7 3.3 0.00017 21.6 0.0 4.2 2 2 2 4 4 4 3 Phosphotransferase enzyme family Kinase-like PF14531.6 KFQ92143.1 - 1.8e-12 47.2 0.0 2.9e-05 23.5 0.0 3.0 2 2 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 KFQ92143.1 - 4.2e-09 35.7 8.4 5e-06 25.5 0.2 3.1 3 0 0 3 3 3 2 Fungal protein kinase Haspin_kinase PF12330.8 KFQ92143.1 - 5.5e-08 32.1 2.7 0.0041 16.1 0.5 2.5 2 0 0 2 2 2 2 Haspin like kinase domain Pkinase_C PF00433.24 KFQ92143.1 - 8.9e-08 32.7 1.1 8.9e-08 32.7 1.1 2.1 2 0 0 2 2 1 1 Protein kinase C terminal domain RIO1 PF01163.22 KFQ92143.1 - 6.2e-07 29.2 1.4 8.4e-05 22.2 0.2 2.5 2 0 0 2 2 2 2 RIO1 family FTA2 PF13095.6 KFQ92143.1 - 2e-06 27.6 1.3 1.2 8.7 0.0 3.6 3 1 0 3 3 3 3 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 KFQ92143.1 - 0.0019 17.8 2.2 0.014 14.9 0.0 2.9 3 0 0 3 3 3 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 KFQ92143.1 - 0.091 12.3 2.7 0.81 9.2 0.1 2.8 2 2 1 3 3 3 0 PhoP regulatory network protein YrbL SR-25 PF10500.9 KFQ92143.1 - 0.093 12.3 7.0 0.2 11.3 7.0 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CaMBD PF02888.16 KFQ92143.1 - 0.36 11.0 2.1 5.9 7.1 0.4 2.4 2 0 0 2 2 2 0 Calmodulin binding domain EF-hand_1 PF00036.32 KFQ92144.1 - 9e-44 143.8 9.7 4.2e-10 38.4 0.4 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFQ92144.1 - 3.8e-37 126.6 2.5 2.5e-19 69.5 0.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFQ92144.1 - 4.5e-35 119.3 9.8 4.8e-15 55.1 0.3 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KFQ92144.1 - 8.5e-32 106.4 4.9 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFQ92144.1 - 1.1e-27 94.3 6.8 1.2e-06 27.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KFQ92144.1 - 7.5e-16 58.2 0.2 2.3e-09 37.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KFQ92144.1 - 2.5e-10 40.2 0.4 5.1e-05 23.2 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFQ92144.1 - 3.7e-08 33.7 0.0 0.0036 17.6 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 KFQ92144.1 - 2e-06 28.6 0.0 0.00083 20.2 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 KFQ92144.1 - 1.1e-05 25.3 0.0 0.042 13.9 0.0 3.1 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KFQ92144.1 - 1.5e-05 25.0 1.0 8.1e-05 22.6 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 KFQ92144.1 - 0.00024 21.2 4.5 0.036 14.2 0.3 3.0 1 1 2 3 3 3 2 Dockerin type I domain DUF1103 PF06513.11 KFQ92144.1 - 0.00071 19.3 1.4 0.00082 19.0 1.4 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.13 KFQ92144.1 - 0.00084 19.3 0.8 0.83 9.6 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein DUF3349 PF11829.8 KFQ92144.1 - 0.0013 19.5 0.5 2.3 9.1 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) DUF4497 PF14924.6 KFQ92144.1 - 0.002 18.6 0.0 0.88 10.1 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) TerB PF05099.13 KFQ92144.1 - 0.0024 17.9 0.8 0.57 10.1 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.16 KFQ92144.1 - 0.0031 17.8 0.7 1.7 9.0 0.1 2.6 3 0 0 3 3 2 1 RNA polymerase Rpb4 DUF5580 PF17743.1 KFQ92144.1 - 0.0056 15.3 0.0 0.0056 15.3 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 KFQ92144.1 - 0.0074 16.2 0.8 0.39 10.6 0.2 2.2 1 1 1 2 2 2 1 SurA N-terminal domain Poly_export PF02563.16 KFQ92144.1 - 0.011 15.9 0.1 0.56 10.5 0.0 3.0 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein EF-hand_14 PF17959.1 KFQ92144.1 - 0.024 15.0 0.1 9.1 6.7 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain SurA_N_3 PF13624.6 KFQ92144.1 - 0.043 13.6 0.4 0.56 10.0 0.2 2.0 1 1 1 2 2 2 0 SurA N-terminal domain Fe_hyd_lg_C PF02906.14 KFQ92144.1 - 0.044 13.4 0.8 0.19 11.3 0.8 1.9 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain MotA_activ PF09114.10 KFQ92144.1 - 0.052 13.7 0.3 0.95 9.6 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 KFQ92144.1 - 0.077 12.2 0.2 6.8 5.8 0.1 2.4 1 1 1 2 2 2 0 Cache domain TetR_C_7 PF14246.6 KFQ92144.1 - 0.083 12.9 0.1 7.2 6.7 0.0 2.8 2 1 1 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain RuvA_C PF07499.13 KFQ92144.1 - 0.13 12.8 0.1 13 6.4 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain CMD PF02627.20 KFQ92144.1 - 0.29 11.2 1.0 7 6.8 0.0 2.8 2 2 1 4 4 3 0 Carboxymuconolactone decarboxylase family SapB_1 PF05184.15 KFQ92144.1 - 0.37 10.9 1.6 27 4.9 0.0 3.4 4 0 0 4 4 4 0 Saposin-like type B, region 1 NRDE-2 PF08424.10 KFQ92145.1 - 2.9e-107 358.5 1.5 2.9e-107 358.5 1.5 4.3 5 1 1 6 6 6 3 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KFQ92145.1 - 1.2e-09 38.1 2.0 0.28 12.1 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ92145.1 - 3.4e-05 24.3 0.6 0.6 10.7 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFQ92145.1 - 0.18 12.5 0.9 55 4.7 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Dsh_C PF12316.8 KFQ92145.1 - 0.42 11.0 6.4 0.81 10.1 6.4 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal TPR_2 PF07719.17 KFQ92145.1 - 5.4 7.4 10.2 4.3 7.7 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat AAA PF00004.29 KFQ92146.1 - 2.2e-41 141.4 0.0 5.7e-41 140.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFQ92146.1 - 5.7e-11 42.1 0.6 1e-10 41.2 0.6 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KFQ92146.1 - 5.2e-10 39.1 0.2 1e-09 38.2 0.2 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KFQ92146.1 - 4.5e-07 30.1 0.1 1.3e-06 28.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFQ92146.1 - 2.2e-06 28.0 0.2 0.0044 17.3 0.0 2.4 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.13 KFQ92146.1 - 2.3e-05 23.7 0.0 4.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KFQ92146.1 - 3.3e-05 23.9 0.4 0.00026 21.0 0.2 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFQ92146.1 - 5.4e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFQ92146.1 - 7.8e-05 23.1 0.1 0.0027 18.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain ATPase PF06745.13 KFQ92146.1 - 0.0017 17.7 0.2 0.26 10.6 0.0 2.5 2 1 1 3 3 2 1 KaiC IstB_IS21 PF01695.17 KFQ92146.1 - 0.0022 17.8 0.0 0.0052 16.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 KFQ92146.1 - 0.0039 17.3 0.0 0.0081 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFQ92146.1 - 0.0055 17.2 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KFQ92146.1 - 0.0057 16.5 0.1 0.1 12.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KFQ92146.1 - 0.0061 16.8 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KFQ92146.1 - 0.007 16.7 0.0 0.017 15.5 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 KFQ92146.1 - 0.0091 15.6 0.3 0.32 10.5 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 KFQ92146.1 - 0.014 15.4 0.0 0.038 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KFQ92146.1 - 0.015 14.6 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 KFQ92146.1 - 0.015 14.7 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Prot_ATP_OB_N PF17758.1 KFQ92146.1 - 0.019 14.6 0.1 0.06 13.0 0.0 1.9 2 0 0 2 2 1 0 Proteasomal ATPase OB N-terminal domain PhoH PF02562.16 KFQ92146.1 - 0.032 13.7 0.0 0.079 12.4 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 KFQ92146.1 - 0.032 13.7 0.0 0.096 12.2 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KFQ92146.1 - 0.035 14.0 0.1 0.57 10.1 0.0 2.6 2 1 1 3 3 2 0 NACHT domain AAA_11 PF13086.6 KFQ92146.1 - 0.037 13.8 0.3 1 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 KFQ92146.1 - 0.049 13.8 0.0 10 6.2 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase AAA_24 PF13479.6 KFQ92146.1 - 0.063 13.0 1.4 0.092 12.5 0.2 1.9 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFQ92146.1 - 0.065 12.9 0.2 0.16 11.7 0.2 1.6 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KFQ92146.1 - 0.067 13.1 0.6 1.8 8.4 0.0 2.9 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KFQ92146.1 - 0.075 12.2 0.1 0.51 9.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain DivIC PF04977.15 KFQ92146.1 - 0.079 12.7 0.1 2.2 8.1 0.3 2.3 2 0 0 2 2 2 0 Septum formation initiator ABC_tran PF00005.27 KFQ92146.1 - 0.087 13.3 0.1 0.38 11.3 0.0 2.2 2 1 0 2 2 2 0 ABC transporter TsaE PF02367.17 KFQ92146.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 KFQ92146.1 - 0.11 11.5 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 KFQ92146.1 - 0.14 11.8 0.0 0.58 9.8 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain Ion_trans_2 PF07885.16 KFQ92147.1 - 6.5e-19 67.7 23.2 1e-14 54.2 8.3 2.3 2 0 0 2 2 2 2 Ion channel LPG_synthase_TM PF03706.13 KFQ92147.1 - 0.07 12.7 1.6 0.12 11.9 1.6 1.4 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region Ion_trans PF00520.31 KFQ92147.1 - 0.33 10.2 16.5 0.071 12.3 5.4 2.2 2 0 0 2 2 2 0 Ion transport protein Tyr-DNA_phospho PF06087.12 KFQ92148.1 - 1.2e-138 462.7 0.0 1.5e-138 462.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase TPR_2 PF07719.17 KFQ92150.1 - 5e-25 85.6 12.2 0.00082 19.3 0.1 8.5 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ92150.1 - 8.9e-22 76.0 16.3 0.00089 19.0 0.3 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ92150.1 - 4.2e-17 62.2 10.4 0.00038 20.7 0.3 6.1 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ92150.1 - 6.1e-16 57.2 9.3 0.014 15.5 0.0 6.6 8 0 0 8 8 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ92150.1 - 5.3e-15 54.8 2.7 0.007 17.1 0.0 7.3 3 2 5 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ92150.1 - 4.7e-11 43.0 10.1 0.0065 17.0 0.0 5.5 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ92150.1 - 7e-10 38.2 11.4 0.042 13.9 0.0 6.9 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ92150.1 - 2.6e-09 37.6 10.0 0.051 14.2 0.5 6.4 7 2 1 8 8 6 3 Tetratricopeptide repeat TPR_15 PF13429.6 KFQ92150.1 - 4.4e-07 29.4 5.1 7.9e-07 28.6 1.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ92150.1 - 8.4e-07 29.0 10.3 0.013 15.8 0.2 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFQ92150.1 - 1.8e-05 24.8 1.2 0.18 12.0 0.1 4.6 2 2 3 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFQ92150.1 - 2.9e-05 24.4 16.1 2 9.2 0.4 7.0 8 1 0 8 8 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ92150.1 - 0.00035 20.3 6.0 0.11 12.4 0.8 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ92150.1 - 0.0015 18.2 12.0 2.4 7.9 0.9 5.7 3 1 2 5 5 5 1 TPR repeat ANAPC3 PF12895.7 KFQ92150.1 - 0.018 15.3 1.4 0.018 15.3 1.4 4.4 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 KFQ92150.1 - 0.028 13.4 4.0 1.4 7.7 0.0 3.1 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 KFQ92150.1 - 0.071 13.8 0.3 9 7.2 0.2 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF5112 PF17139.4 KFQ92150.1 - 3.3 7.1 9.2 0.31 10.5 0.3 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF5112) WD40 PF00400.32 KFQ92151.1 - 5e-63 207.5 84.7 1.2e-05 25.9 0.1 27.2 30 0 0 30 30 30 15 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ92151.1 - 1.4e-38 131.1 6.9 1.3e-07 31.8 0.0 13.2 8 3 4 13 13 13 7 Anaphase-promoting complex subunit 4 WD40 domain HELP PF03451.14 KFQ92151.1 - 3.9e-38 129.2 0.2 7.1e-20 70.6 0.0 2.4 2 0 0 2 2 2 2 HELP motif Ge1_WD40 PF16529.5 KFQ92151.1 - 7.4e-07 28.4 3.9 0.37 9.7 0.0 6.8 4 3 3 7 7 7 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KFQ92151.1 - 1.5e-05 23.9 0.0 0.11 11.2 0.0 4.0 4 0 0 4 4 4 2 Nup133 N terminal like Cytochrom_D1 PF02239.16 KFQ92151.1 - 5.6e-05 21.8 10.9 0.16 10.5 0.0 6.7 7 1 1 8 8 8 2 Cytochrome D1 heme domain Frtz PF11768.8 KFQ92151.1 - 0.00058 18.3 0.0 1.3 7.2 0.0 4.0 4 0 0 4 4 4 2 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 KFQ92151.1 - 0.032 12.9 0.0 6.8 5.2 0.0 3.3 3 0 0 3 3 3 0 Nucleoporin Nup120/160 PD40 PF07676.12 KFQ92151.1 - 0.12 12.3 1.3 2.1e+02 2.0 0.0 4.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat zf-CCCH_2 PF14608.6 KFQ92152.1 - 9.5e-18 64.0 57.9 0.00013 22.3 7.4 5.4 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger PWI PF01480.17 KFQ92152.1 - 0.051 13.9 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 PWI domain Perm-CXXC PF15629.6 KFQ92152.1 - 0.1 12.9 1.9 0.33 11.3 1.9 1.9 1 0 0 1 1 1 0 Permuted single zf-CXXC unit DAHP_snth_FXD PF18152.1 KFQ92152.1 - 0.51 10.2 2.5 1.3 8.9 0.1 2.5 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain Y_phosphatase PF00102.27 KFQ92153.1 - 1.8e-74 250.3 0.7 3.2e-74 249.5 0.1 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase FERM_M PF00373.18 KFQ92153.1 - 3.5e-20 72.6 2.3 1.1e-19 71.0 2.3 1.9 1 0 0 1 1 1 1 FERM central domain FERM_C PF09380.10 KFQ92153.1 - 6.7e-18 64.9 0.2 1.6e-17 63.6 0.2 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KFQ92153.1 - 4.2e-16 58.6 1.7 1e-15 57.4 0.2 2.5 3 0 0 3 3 3 1 FERM N-terminal domain DSPc PF00782.20 KFQ92153.1 - 3.9e-06 26.7 0.0 9.6e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFQ92153.1 - 0.00069 19.6 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family HSD3 PF15244.6 KFQ92154.1 - 6.2e-36 124.8 4.2 6.2e-36 124.8 4.2 1.4 2 0 0 2 2 2 1 Spermatogenesis-associated protein 7, or HSD3 CARD PF00619.21 KFQ92154.1 - 0.012 15.7 1.0 0.043 13.8 0.2 2.0 2 0 0 2 2 2 0 Caspase recruitment domain PUF PF00806.19 KFQ92154.1 - 0.021 14.5 0.1 0.07 12.8 0.1 1.9 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat Ion_trans_2 PF07885.16 KFQ92155.1 - 2.8e-37 126.5 22.7 5.9e-19 67.8 9.9 3.3 3 1 1 4 4 4 2 Ion channel Ion_trans PF00520.31 KFQ92155.1 - 4.5e-07 29.4 11.1 1.1e-06 28.1 0.3 2.5 2 1 0 2 2 2 1 Ion transport protein DUF2390 PF09523.10 KFQ92155.1 - 0.029 14.7 0.4 0.029 14.7 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) PLC-beta_C PF08703.10 KFQ92155.1 - 0.03 14.3 0.2 0.058 13.4 0.2 1.4 1 0 0 1 1 1 0 PLC-beta C terminal PDZ_3 PF17815.1 KFQ92155.1 - 0.079 12.8 0.2 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 PDZ domain TssN PF17555.2 KFQ92155.1 - 0.084 12.3 4.3 0.37 10.1 2.4 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssN Docking PF08990.11 KFQ92155.1 - 0.18 11.4 0.3 0.33 10.6 0.3 1.4 1 0 0 1 1 1 0 Erythronolide synthase docking E1-E2_ATPase PF00122.20 KFQ92155.1 - 0.44 10.1 4.6 0.61 9.6 0.9 2.4 2 0 0 2 2 2 0 E1-E2 ATPase Pox_A14 PF05767.12 KFQ92155.1 - 4.7 7.4 6.2 28 4.9 0.9 3.0 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 7tm_1 PF00001.21 KFQ92157.1 - 1.3e-43 149.3 20.4 1.7e-43 148.8 20.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFQ92157.1 - 0.0013 18.5 16.7 0.0018 18.1 16.7 1.2 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFQ92157.1 - 0.0015 18.2 11.3 0.0015 18.2 11.3 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Str PF10326.9 KFQ92157.1 - 0.13 11.6 20.9 0.43 9.9 3.4 2.9 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Str DUF2975 PF11188.8 KFQ92157.1 - 1.4 8.8 10.8 0.72 9.7 0.4 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2975) Glyco_hydro_59 PF02057.15 KFQ92158.1 - 8.2e-109 363.4 1.2 1.1e-108 363.0 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_59M PF17387.2 KFQ92158.1 - 1.8e-51 173.2 0.0 3.8e-51 172.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 central domain CRCB PF02537.15 KFQ92158.1 - 0.1 12.9 0.2 2.5 8.4 0.0 2.4 2 0 0 2 2 2 0 CrcB-like protein, Camphor Resistance (CrcB) Laminin_G_3 PF13385.6 KFQ92158.1 - 0.35 11.0 3.6 0.21 11.7 1.1 1.9 2 0 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily RLAN PF14401.6 KFQ92160.1 - 0.17 11.6 0.0 0.19 11.4 0.0 1.0 1 0 0 1 1 1 0 RimK-like ATPgrasp N-terminal domain LRR_8 PF13855.6 KFQ92161.1 - 9.4e-33 111.8 30.6 2.8e-13 49.4 6.4 5.4 3 1 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 KFQ92161.1 - 2.4e-18 65.9 29.5 0.00012 22.4 2.7 7.4 3 1 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFQ92161.1 - 4.6e-10 39.6 0.0 3.3e-06 27.1 0.0 3.5 2 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFQ92161.1 - 1.2e-06 28.2 8.9 0.024 14.1 0.1 3.3 2 1 1 3 3 3 3 Leucine-rich repeat LRRNT PF01462.18 KFQ92161.1 - 7.8e-05 22.2 2.6 7.8e-05 22.2 2.6 3.7 5 0 0 5 5 5 1 Leucine rich repeat N-terminal domain LRRCT PF01463.24 KFQ92161.1 - 0.00023 21.5 0.1 0.00069 20.0 0.1 1.9 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain fn3 PF00041.21 KFQ92161.1 - 0.00029 21.1 0.0 0.00077 19.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain LRR_1 PF00560.33 KFQ92161.1 - 0.00072 19.8 17.3 2.9 8.8 0.1 9.1 10 1 0 10 10 10 1 Leucine Rich Repeat LRR_6 PF13516.6 KFQ92161.1 - 0.083 13.0 26.5 1.4 9.2 0.2 7.4 8 0 0 8 8 8 0 Leucine Rich repeat Syndecan PF01034.20 KFQ92161.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain BAMBI PF06211.12 KFQ92164.1 - 2.3e-46 156.5 11.4 2.3e-46 156.5 11.4 1.6 2 0 0 2 2 2 1 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain LapA_dom PF06305.11 KFQ92164.1 - 0.052 13.4 0.9 0.079 12.8 0.9 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain JIP_LZII PF16471.5 KFQ92164.1 - 0.067 13.4 0.4 14 6.0 0.0 2.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II EphA2_TM PF14575.6 KFQ92164.1 - 0.08 13.8 0.0 0.18 12.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain KASH PF10541.9 KFQ92164.1 - 0.97 9.8 3.9 6.6 7.1 0.2 2.5 2 0 0 2 2 2 0 Nuclear envelope localisation domain Pkinase PF00069.25 KFQ92165.1 - 5.1e-49 167.0 0.0 9.5e-49 166.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ92165.1 - 1.4e-25 90.0 0.0 3.3e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFQ92165.1 - 1.6e-05 23.9 0.0 2.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFQ92165.1 - 0.012 15.5 0.0 0.027 14.4 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KFQ92165.1 - 0.038 13.3 0.0 5.6 6.2 0.0 2.2 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.22 KFQ92165.1 - 0.083 12.5 0.1 0.24 11.0 0.1 1.8 1 1 1 2 2 2 0 RIO1 family RL PF17797.1 KFQ92166.1 - 9.6e-35 118.4 0.1 2.3e-34 117.2 0.1 1.7 1 0 0 1 1 1 1 RL domain PAP_assoc PF03828.19 KFQ92166.1 - 7.3e-07 29.3 0.1 2.4e-06 27.6 0.1 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase JCAD PF15351.6 KFQ92167.1 - 0 1831.5 61.3 0 1831.3 61.3 1.0 1 0 0 1 1 1 1 Junctional protein associated with coronary artery disease Gelsolin PF00626.22 KFQ92168.1 - 1.4e-21 76.1 0.5 7.8e-07 28.9 0.0 5.7 5 0 0 5 5 5 4 Gelsolin repeat VHP PF02209.19 KFQ92168.1 - 1.6e-16 60.1 0.1 4.3e-16 58.7 0.1 1.8 1 0 0 1 1 1 1 Villin headpiece domain DUF4695 PF15766.5 KFQ92168.1 - 3.6e-09 36.8 6.7 0.0066 16.6 0.0 4.7 3 0 0 3 3 3 3 Domain of unknown function (DUF4695) zf-H2C2_2 PF13465.6 KFQ92169.1 - 1.9e-07 31.2 35.0 0.00018 21.8 4.6 5.2 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ92169.1 - 0.0034 18.1 46.9 0.062 14.2 3.5 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KFQ92169.1 - 0.022 15.2 43.8 0.042 14.3 4.1 5.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ92170.1 - 1.6e-30 104.1 54.5 6.2e-08 32.7 2.5 7.9 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ92170.1 - 3.4e-24 83.9 66.3 0.0001 22.5 5.0 7.7 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ92170.1 - 2.2e-14 52.9 64.1 0.028 15.2 4.4 8.1 8 0 0 8 8 8 7 C2H2-type zinc finger zf-met PF12874.7 KFQ92170.1 - 4.1e-09 36.5 46.1 0.015 15.6 1.2 6.8 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFQ92170.1 - 1.1e-08 35.2 26.0 1.4e-07 31.6 1.3 3.9 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KFQ92170.1 - 9.2e-08 32.2 54.6 0.0088 16.3 1.9 7.9 8 0 0 8 8 7 5 Zinc-finger double-stranded RNA-binding Homeodomain PF00046.29 KFQ92170.1 - 3.8e-05 23.5 0.0 9.7e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Homeodomain zf-C2H2_6 PF13912.6 KFQ92170.1 - 0.013 15.4 60.9 0.51 10.4 0.9 7.5 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2HE PF16278.5 KFQ92170.1 - 0.08 13.4 0.1 0.08 13.4 0.1 7.1 3 2 2 5 5 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_9 PF16293.5 KFQ92170.1 - 0.15 12.0 15.8 5 7.0 0.0 5.3 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 KFQ92170.1 - 0.42 11.0 44.6 0.12 12.7 1.9 7.0 3 2 4 7 7 7 0 C2H2 type zinc-finger (2 copies) TRAF6_Z2 PF18048.1 KFQ92170.1 - 3.6 7.7 15.4 32 4.7 0.5 5.4 6 0 0 6 6 6 0 TNF receptor-associated factor 6 zinc finger 2 RVT_1 PF00078.27 KFQ92171.1 - 0.027 14.0 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) SH3-WW_linker PF16618.5 KFQ92172.1 - 3.4e-64 217.0 12.1 3.4e-64 217.0 12.1 3.0 3 0 0 3 3 3 1 Linker region between SH3 and WW domains on ARHGAP12 RhoGAP PF00620.27 KFQ92172.1 - 1.5e-50 170.9 1.2 1.6e-50 170.9 0.1 1.6 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 KFQ92172.1 - 5.9e-09 36.4 0.3 2.9e-08 34.2 0.3 2.3 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.6 KFQ92172.1 - 4.1e-08 33.0 0.2 1.1e-07 31.6 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain PH_9 PF15410.6 KFQ92172.1 - 6.6e-07 29.7 0.1 2e-06 28.2 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_1 PF00018.28 KFQ92172.1 - 8.1e-07 28.6 3.5 5.3e-06 26.0 0.9 2.6 2 0 0 2 2 2 1 SH3 domain WW PF00397.26 KFQ92172.1 - 7e-05 22.8 25.4 0.0009 19.3 5.5 4.4 3 1 1 4 4 4 2 WW domain SH3_10 PF17902.1 KFQ92172.1 - 0.022 14.8 0.4 0.086 12.9 0.1 2.1 2 0 0 2 2 2 0 SH3 domain SH3_3 PF08239.11 KFQ92172.1 - 0.14 12.5 2.0 1.6 9.1 0.4 2.9 2 0 0 2 2 2 0 Bacterial SH3 domain Glyco_hyd_101C PF17451.2 KFQ92172.1 - 0.88 9.9 14.2 0.67 10.3 0.6 4.0 5 0 0 5 5 5 0 Glycosyl hydrolase 101 beta sandwich domain Kinesin PF00225.23 KFQ92173.1 - 6.2e-111 370.5 2.5 6.2e-111 370.5 2.5 2.9 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KFQ92173.1 - 4e-24 85.3 0.2 4e-24 85.3 0.2 3.5 4 1 0 4 4 4 1 Microtubule binding APG6_N PF17675.1 KFQ92173.1 - 0.014 15.9 24.6 0.014 15.9 24.6 5.7 2 2 3 5 5 5 0 Apg6 coiled-coil region DUF4226 PF10774.9 KFQ92173.1 - 0.028 14.7 1.3 0.028 14.7 1.3 5.6 3 1 2 6 6 6 0 Domain of unknown function (DUF4226) Cation_ATPase PF13246.6 KFQ92173.1 - 4.4 7.5 7.4 4.9 7.3 0.5 3.9 3 1 0 3 3 3 0 Cation transport ATPase (P-type) E_Pc_C PF06752.12 KFQ92174.1 - 5.2e-98 327.7 43.9 5.2e-98 327.7 43.9 2.3 2 1 0 2 2 2 1 Enhancer of Polycomb C-terminus EPL1 PF10513.9 KFQ92174.1 - 4.5e-06 27.1 0.7 4.5e-06 27.1 0.7 3.6 5 0 0 5 5 5 1 Enhancer of polycomb-like CAF1A PF12253.8 KFQ92174.1 - 0.11 12.7 0.6 0.44 10.7 0.1 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A PKK PF12474.8 KFQ92174.1 - 1.1 9.4 19.1 0.084 13.0 4.1 2.8 2 0 0 2 2 2 0 Polo kinase kinase Integrin_beta PF00362.18 KFQ92175.1 - 2.8e-116 387.5 0.1 3.8e-116 387.0 0.1 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_B_tail PF07965.12 KFQ92175.1 - 5e-22 78.2 8.4 5e-22 78.2 8.4 4.3 5 1 1 6 6 6 1 Integrin beta tail domain I-EGF_1 PF18372.1 KFQ92175.1 - 1.5e-12 47.3 12.1 1.5e-12 47.3 12.1 7.2 9 0 0 9 9 9 3 Integrin beta epidermal growth factor like domain 1 PSI_integrin PF17205.3 KFQ92175.1 - 1.9e-12 46.7 7.4 1.9e-12 46.7 7.4 4.5 3 1 1 4 4 4 1 Integrin plexin domain Integrin_b_cyt PF08725.11 KFQ92175.1 - 5.6e-10 38.7 0.7 9.8e-10 38.0 0.7 1.4 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain EGF_2 PF07974.13 KFQ92175.1 - 2.4e-08 34.2 59.7 6.4e-06 26.4 16.5 6.8 6 1 1 7 7 7 3 EGF-like domain CUB PF00431.20 KFQ92176.1 - 1.7e-58 195.7 0.0 1e-28 99.9 0.0 2.7 2 0 0 2 2 2 2 CUB domain F5_F8_type_C PF00754.25 KFQ92176.1 - 5.9e-54 181.6 3.8 2.3e-28 98.9 0.1 2.8 3 0 0 3 3 3 2 F5/8 type C domain DUF3481 PF11980.8 KFQ92176.1 - 9.7e-48 159.8 0.2 1.9e-47 158.9 0.2 1.5 1 0 0 1 1 1 1 C-terminal domain of neuropilin glycoprotein MAM PF00629.23 KFQ92176.1 - 8.5e-40 136.3 1.3 1.8e-39 135.3 1.3 1.6 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu PDZ PF00595.24 KFQ92177.1 - 3.2e-37 126.7 4.8 2.4e-15 56.7 0.1 3.6 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 KFQ92177.1 - 5.6e-19 67.7 0.0 5.6e-07 29.3 0.1 3.7 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 KFQ92177.1 - 6.9e-15 55.1 0.3 4.7e-06 26.8 0.1 3.8 3 0 0 3 3 3 3 PDZ domain bZIP_1 PF00170.21 KFQ92179.1 - 3.1e-20 72.0 11.7 5e-20 71.4 11.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor pKID PF02173.17 KFQ92179.1 - 9.3e-20 69.8 2.8 2.4e-19 68.5 2.8 1.7 1 0 0 1 1 1 1 pKID domain bZIP_2 PF07716.15 KFQ92179.1 - 3e-07 30.4 11.0 5.1e-07 29.7 11.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFQ92179.1 - 0.0031 18.0 6.2 0.0062 17.0 6.2 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor MMgT PF10270.9 KFQ92179.1 - 0.12 12.7 0.1 1.9 8.9 0.0 2.2 2 0 0 2 2 2 0 Membrane magnesium transporter Cyclin_N PF00134.23 KFQ92180.1 - 9.7e-15 54.4 0.1 1.7e-14 53.7 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KFQ92180.1 - 1.1e-11 45.4 0.1 1.4e-11 45.0 0.1 1.3 1 0 0 1 1 1 1 Cyclin Frizzled PF01534.17 KFQ92181.1 - 5.9e-69 232.6 7.1 9.1e-46 156.4 5.9 2.0 1 1 1 2 2 2 2 Frizzled/Smoothened family membrane region Dicty_CAR PF05462.11 KFQ92181.1 - 0.029 13.5 1.3 0.042 13.0 1.3 1.2 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor zf-C2H2 PF00096.26 KFQ92182.1 - 9.2e-14 51.0 31.7 7.9e-05 22.9 8.9 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ92182.1 - 3.1e-10 40.0 13.7 1.8e-06 28.1 6.5 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ92182.1 - 1.8e-06 28.3 28.4 0.0091 16.8 7.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger DUF3850 PF12961.7 KFQ92182.1 - 0.076 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) zf-C2H2_8 PF15909.5 KFQ92182.1 - 1.7 9.0 12.6 0.37 11.1 6.7 2.7 2 1 1 3 3 3 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 KFQ92182.1 - 1.7 9.3 9.3 1.3 9.7 0.8 2.9 1 1 2 3 3 3 0 FOXP coiled-coil domain DUF4692 PF15763.5 KFQ92182.1 - 1.9 8.9 7.3 2.2 8.7 6.6 1.6 1 1 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) zf-C2H2_jaz PF12171.8 KFQ92182.1 - 2.9 8.3 9.1 8.1 6.9 1.7 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding M16C_assoc PF08367.11 KFQ92184.1 - 3.2e-87 291.8 0.0 5.7e-87 291.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KFQ92184.1 - 1.4e-30 106.7 1.3 4.5e-22 78.9 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KFQ92184.1 - 1.7e-09 37.8 1.0 2.3e-05 24.4 0.0 3.6 5 0 0 5 5 5 2 Insulinase (Peptidase family M16) KMP11 PF03037.16 KFQ92184.1 - 0.52 11.1 12.9 0.11 13.3 3.2 3.2 3 0 0 3 3 3 0 Kinetoplastid membrane protein 11 PFK PF00365.20 KFQ92186.1 - 3.6e-204 676.2 7.5 1.8e-111 372.0 1.6 2.1 2 0 0 2 2 2 2 Phosphofructokinase A_deamin PF02137.18 KFQ92189.1 - 6e-109 364.5 0.0 9e-109 363.9 0.0 1.3 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.26 KFQ92189.1 - 1.4e-24 86.5 0.1 4e-11 43.5 0.0 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KFQ92189.1 - 0.057 13.7 1.0 3.2 8.1 0.0 3.0 2 1 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 WD40 PF00400.32 KFQ92190.1 - 5.9e-27 93.4 23.7 5.3e-07 30.2 0.4 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ92190.1 - 0.019 15.2 3.3 3.6 8.0 0.1 4.2 4 2 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1640 PF07798.11 KFQ92190.1 - 0.073 13.1 2.7 0.12 12.4 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) FAM76 PF16046.5 KFQ92190.1 - 0.91 8.8 5.8 1.5 8.1 5.8 1.2 1 0 0 1 1 1 0 FAM76 protein NUDIX PF00293.28 KFQ92191.1 - 1.7e-24 86.4 0.0 2.2e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain La PF05383.17 KFQ92192.1 - 3.7e-14 52.5 0.2 7.9e-14 51.4 0.2 1.6 1 0 0 1 1 1 1 La domain AMP-binding PF00501.28 KFQ92193.1 - 7e-97 324.7 0.0 7.3e-74 248.9 0.0 2.6 2 1 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.11 KFQ92193.1 - 8.3e-06 26.6 0.2 1.5e-05 25.8 0.2 1.4 1 0 0 1 1 1 1 DMAP1-binding Domain Bromodomain PF00439.25 KFQ92194.1 - 1.4e-10 41.1 0.9 2.6e-10 40.2 0.2 1.9 2 0 0 2 2 2 1 Bromodomain PWWP PF00855.17 KFQ92194.1 - 3.9e-10 40.0 0.3 3.9e-10 40.0 0.3 3.7 3 1 0 3 3 3 1 PWWP domain zf-MYND PF01753.18 KFQ92194.1 - 0.016 15.3 22.1 0.016 15.3 22.1 4.0 3 1 0 3 3 3 0 MYND finger 7tm_2 PF00002.24 KFQ92196.1 - 3.8e-84 281.8 11.6 5.2e-84 281.4 11.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFQ92196.1 - 1.8e-22 79.4 2.3 1.8e-22 79.4 2.3 2.3 2 0 0 2 2 2 1 Hormone receptor domain POLO_box PF00659.18 KFQ92196.1 - 0.0002 21.5 0.2 0.00054 20.1 0.2 1.7 1 0 0 1 1 1 1 POLO box duplicated region SMP_LBD PF17047.5 KFQ92197.1 - 3.6e-121 401.3 0.7 5.3e-121 400.7 0.7 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 KFQ92197.1 - 3.1e-55 184.8 0.0 5.8e-21 74.7 0.0 3.6 3 0 0 3 3 3 3 C2 domain Condensin2nSMC PF12422.8 KFQ92198.1 - 1.8e-57 193.7 4.6 1.6e-56 190.6 0.8 3.6 3 0 0 3 3 3 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.22 KFQ92198.1 - 6.6e-08 32.2 0.1 2.2 8.8 0.0 5.3 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 KFQ92198.1 - 0.00036 20.9 0.0 0.63 10.5 0.0 3.3 1 1 2 3 3 3 2 HEAT repeats Cnd1 PF12717.7 KFQ92198.1 - 0.001 19.2 0.1 0.048 13.7 0.0 4.6 4 1 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KFQ92198.1 - 0.0011 17.7 0.1 0.0011 17.7 0.1 1.8 2 0 0 2 2 2 1 Adaptin N terminal region DUF577 PF04510.12 KFQ92198.1 - 0.0017 18.3 2.7 0.62 10.0 0.0 4.3 3 1 1 4 4 4 1 Family of unknown function (DUF577) TIP120 PF08623.10 KFQ92198.1 - 0.012 15.4 0.7 0.36 10.6 0.0 3.1 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) Vac14_Fab1_bd PF12755.7 KFQ92198.1 - 0.087 13.4 1.0 2.7 8.7 0.0 3.7 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Y_phosphatase PF00102.27 KFQ92201.1 - 6.3e-74 248.5 0.2 9e-74 248.0 0.2 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFQ92201.1 - 0.0012 18.6 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DnaJ PF00226.31 KFQ92203.1 - 8.6e-29 99.5 4.6 1.4e-28 98.8 4.6 1.4 1 0 0 1 1 1 1 DnaJ domain HECT PF00632.25 KFQ92204.1 - 2e-96 323.1 0.0 3.5e-96 322.3 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KFQ92204.1 - 0.00036 20.1 0.1 0.00096 18.8 0.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif MA3 PF02847.17 KFQ92206.1 - 1.5e-26 92.6 2.4 3.6e-26 91.4 1.3 2.4 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 KFQ92206.1 - 2.1e-20 73.3 6.4 2.1e-20 73.3 6.4 2.3 2 0 0 2 2 2 1 MIF4G domain LMBR1 PF04791.16 KFQ92207.1 - 2.9e-91 306.9 26.8 3.7e-55 187.8 14.3 2.0 1 1 1 2 2 2 2 LMBR1-like membrane protein Orf78 PF06024.12 KFQ92207.1 - 0.022 15.0 0.4 0.022 15.0 0.4 3.7 4 0 0 4 4 4 0 Orf78 (ac78) Sigma_reg_N PF13800.6 KFQ92207.1 - 0.1 12.9 0.1 0.1 12.9 0.1 4.6 5 1 0 5 5 5 0 Sigma factor regulator N-terminal CrgA PF06781.12 KFQ92207.1 - 9.6 6.3 8.5 2.8 8.0 0.6 3.5 4 0 0 4 4 4 0 Cell division protein CrgA Hint PF01079.20 KFQ92208.1 - 1.6e-76 256.5 0.0 2e-76 256.2 0.0 1.1 1 0 0 1 1 1 1 Hint module HH_signal PF01085.18 KFQ92208.1 - 2.7e-41 140.9 0.0 9.9e-32 109.8 0.0 2.2 2 0 0 2 2 2 2 Hedgehog amino-terminal signalling domain RRM_1 PF00076.22 KFQ92209.1 - 0.0072 16.1 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFQ92209.1 - 0.051 13.5 0.1 0.34 10.8 0.1 2.3 3 0 0 3 3 3 0 Occluded RNA-recognition motif RRM_3 PF08777.11 KFQ92209.1 - 0.59 10.2 0.0 0.59 10.2 0.0 4.3 5 1 1 6 6 6 0 RNA binding motif DUF3456 PF11938.8 KFQ92210.1 - 2.3e-05 25.0 0.2 2.6e-05 24.8 0.2 1.1 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP SapB_2 PF03489.17 KFQ92210.1 - 0.013 15.6 0.1 0.017 15.3 0.1 1.3 1 0 0 1 1 1 0 Saposin-like type B, region 2 MFS_2 PF13347.6 KFQ92212.1 - 6.3e-22 77.7 20.5 2e-19 69.5 20.5 2.8 1 1 0 1 1 1 1 MFS/sugar transport protein Actin PF00022.19 KFQ92213.1 - 3e-132 441.1 0.0 1.4e-131 438.9 0.0 1.7 1 1 0 1 1 1 1 Actin SUFU_C PF12470.8 KFQ92214.1 - 3.9e-83 278.5 0.0 5.2e-83 278.1 0.0 1.2 1 0 0 1 1 1 1 Suppressor of Fused Gli/Ci N terminal binding domain SUFU PF05076.13 KFQ92214.1 - 4.1e-51 173.4 0.0 6e-51 172.8 0.0 1.2 1 0 0 1 1 1 1 Suppressor of fused protein (SUFU) zf-C3HC4_4 PF15227.6 KFQ92215.1 - 1.1e-10 41.4 8.1 1.1e-10 41.4 8.1 3.4 4 0 0 4 4 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KFQ92215.1 - 1.5e-09 37.6 6.5 1.5e-09 37.6 6.5 2.8 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFQ92215.1 - 6e-09 35.8 8.1 6e-09 35.8 8.1 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFQ92215.1 - 6.2e-08 32.4 7.8 2.8e-07 30.3 7.8 2.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ92215.1 - 8e-06 26.1 8.3 8e-06 26.1 8.3 3.3 3 1 0 3 3 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFQ92215.1 - 2.7e-05 23.9 6.0 2.7e-05 23.9 6.0 3.4 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 KFQ92215.1 - 0.00011 22.2 7.5 0.00011 22.2 7.5 5.4 5 1 0 5 5 4 1 B-box zinc finger zf-RING_10 PF16685.5 KFQ92215.1 - 0.0023 18.0 3.9 0.0023 18.0 3.9 3.3 4 1 0 4 4 1 1 zinc RING finger of MSL2 zf-RING_5 PF14634.6 KFQ92215.1 - 0.013 15.5 8.3 0.013 15.5 8.3 4.0 3 2 0 3 3 2 0 zinc-RING finger domain zf-Nse PF11789.8 KFQ92215.1 - 0.02 14.7 4.1 0.06 13.2 4.1 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 KFQ92215.1 - 0.11 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 U-box domain DUF3552 PF12072.8 KFQ92215.1 - 0.39 10.1 14.1 0.7 9.3 14.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) dCache_2 PF08269.11 KFQ92215.1 - 0.91 8.6 4.5 1.4 8.0 4.5 1.2 1 0 0 1 1 1 0 Cache domain Exonuc_VII_L PF02601.15 KFQ92215.1 - 0.92 9.0 4.6 1.3 8.5 4.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phasin PF05597.11 KFQ92215.1 - 1.1 9.3 8.4 1.9 8.5 8.4 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) CASP_C PF08172.12 KFQ92215.1 - 1.4 8.2 10.4 1 8.7 8.2 1.6 1 1 0 1 1 1 0 CASP C terminal DUF1461 PF07314.11 KFQ92215.1 - 1.7 8.5 2.9 2.9 7.8 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) DUF3287 PF11690.8 KFQ92215.1 - 1.9 8.2 5.5 2.5 7.8 4.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) OEP PF02321.18 KFQ92215.1 - 3 7.6 8.7 4.7 7.0 8.7 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein zf-RING_6 PF14835.6 KFQ92215.1 - 4.4 7.3 10.9 0.074 12.9 3.0 2.2 2 0 0 2 2 1 0 zf-RING of BARD1-type protein Zn_ribbon_recom PF13408.6 KFQ92215.1 - 6.6 7.3 9.3 0.94 10.0 0.1 3.6 2 1 0 2 2 1 0 Recombinase zinc beta ribbon domain Arf PF00025.21 KFQ92217.1 - 4.5e-72 241.1 0.0 5e-72 241.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFQ92217.1 - 1.8e-14 53.6 0.0 2e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KFQ92217.1 - 1.8e-14 53.9 0.0 2.5e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KFQ92217.1 - 1.9e-14 53.6 0.3 1.2e-08 34.5 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KFQ92217.1 - 1.7e-13 50.5 0.0 2e-13 50.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KFQ92217.1 - 1e-12 47.9 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFQ92217.1 - 1.2e-08 35.0 0.0 1.7e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFQ92217.1 - 4.8e-05 23.0 0.0 0.0031 17.1 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 KFQ92217.1 - 0.00018 22.0 0.0 0.00025 21.5 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 KFQ92217.1 - 0.0068 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 KFQ92217.1 - 0.01 16.4 0.0 0.017 15.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFQ92217.1 - 0.014 15.3 0.0 5.2 6.9 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_14 PF13173.6 KFQ92217.1 - 0.024 14.7 0.1 0.047 13.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KFQ92217.1 - 0.046 13.6 0.0 7.4 6.5 0.0 2.2 2 0 0 2 2 2 0 NACHT domain FeoB_N PF02421.18 KFQ92217.1 - 0.052 13.1 0.1 0.17 11.4 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B cobW PF02492.19 KFQ92217.1 - 0.06 12.9 0.1 7.8 6.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KFQ92217.1 - 0.081 11.9 0.0 2.8 6.8 0.0 2.5 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KFQ92217.1 - 0.11 12.8 0.1 0.81 10.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFQ92217.1 - 0.13 12.6 0.1 0.61 10.5 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 KFQ92217.1 - 0.15 12.1 0.0 4 7.5 0.0 2.1 1 1 1 2 2 2 0 Dynamin family Mtc PF03820.17 KFQ92218.1 - 4.3e-135 449.8 0.0 4.8e-135 449.6 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier WBP-1 PF11669.8 KFQ92219.1 - 6.5e-45 152.0 12.9 1.3e-44 151.1 12.9 1.5 1 0 0 1 1 1 1 WW domain-binding protein 1 TMIE PF16038.5 KFQ92219.1 - 0.015 15.1 0.6 0.026 14.3 0.6 1.3 1 0 0 1 1 1 0 TMIE protein p450 PF00067.22 KFQ92220.1 - 1e-137 459.7 0.0 1.2e-137 459.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_31 PF13847.6 KFQ92221.1 - 6.2e-32 110.5 0.0 1.1e-31 109.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFQ92221.1 - 8.2e-21 74.5 0.1 4.3e-20 72.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFQ92221.1 - 4e-18 65.9 0.0 1e-17 64.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFQ92221.1 - 3.8e-14 52.6 0.0 5.6e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KFQ92221.1 - 4e-14 52.8 0.0 8.5e-14 51.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFQ92221.1 - 9e-13 48.8 0.0 1.7e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFQ92221.1 - 4.2e-06 26.7 0.0 6.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.15 KFQ92221.1 - 0.00025 21.0 0.0 0.0004 20.3 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 KFQ92221.1 - 0.00089 18.8 0.0 0.0021 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KFQ92221.1 - 0.0024 17.3 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 KFQ92221.1 - 0.0071 15.8 0.0 0.018 14.5 0.0 1.7 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_16 PF10294.9 KFQ92221.1 - 0.033 13.9 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_32 PF13679.6 KFQ92221.1 - 0.056 13.4 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TylF PF05711.11 KFQ92221.1 - 0.15 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) DUF21 PF01595.20 KFQ92222.1 - 4e-29 101.6 0.0 7.1e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KFQ92222.1 - 3.5e-07 30.6 0.2 0.00037 20.9 0.0 2.7 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.29 KFQ92222.1 - 0.00012 22.1 0.0 0.013 15.5 0.0 2.6 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Nrf1_DNA-bind PF10491.9 KFQ92222.1 - 0.093 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 Cupin_3 PF05899.12 KFQ92222.1 - 0.16 11.7 0.1 0.33 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) 5_nucleotid PF05761.14 KFQ92223.1 - 2.4e-176 587.2 0.0 3e-176 586.8 0.0 1.1 1 0 0 1 1 1 1 5' nucleotidase family zf-C3HC4_2 PF13923.6 KFQ92224.1 - 2.4e-10 40.0 9.1 5.2e-10 39.0 9.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ92224.1 - 1.3e-08 34.5 11.0 2.3e-08 33.7 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RAWUL PF16207.5 KFQ92224.1 - 9.6e-07 29.4 0.0 1.8e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-RING_UBOX PF13445.6 KFQ92224.1 - 1.7e-06 27.9 7.7 3.8e-06 26.8 7.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFQ92224.1 - 1.8e-05 24.9 9.8 1.8e-05 24.9 9.8 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFQ92224.1 - 8.4e-05 22.4 8.7 0.00015 21.5 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFQ92224.1 - 0.00021 21.2 10.7 0.00047 20.0 10.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 KFQ92224.1 - 0.0021 17.9 2.6 0.0036 17.1 2.6 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KFQ92224.1 - 0.0071 16.5 6.2 0.022 14.9 4.4 2.2 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 KFQ92224.1 - 0.01 16.0 10.4 0.021 15.0 10.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFQ92224.1 - 0.1 12.4 8.4 0.21 11.5 8.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFQ92224.1 - 0.22 11.9 9.6 0.76 10.1 9.6 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-Nse PF11789.8 KFQ92224.1 - 0.31 10.9 5.4 0.55 10.1 5.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TackOD1 PF18551.1 KFQ92224.1 - 0.48 10.1 9.9 0.18 11.5 2.4 2.5 2 1 1 3 3 3 0 Thaumarchaeal output domain 1 DUF1272 PF06906.11 KFQ92224.1 - 0.99 9.5 6.1 2.5 8.3 6.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_5 PF17121.5 KFQ92224.1 - 1.4 8.9 9.0 4.1 7.4 9.0 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.32 KFQ92225.1 - 2.1e-58 192.9 9.9 2.5e-11 43.9 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KFQ92225.1 - 4.3e-43 146.6 4.6 9.3e-43 145.6 4.6 1.6 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KFQ92225.1 - 3.4e-15 56.1 0.0 0.00036 20.8 0.0 5.4 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFQ92225.1 - 3.6e-09 35.8 0.4 0.0045 15.7 0.0 3.8 4 0 0 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFQ92225.1 - 2.4e-06 26.8 0.0 1.8 7.4 0.0 4.1 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFQ92225.1 - 0.0039 16.6 0.0 1.4 8.2 0.0 3.6 4 1 1 5 5 5 1 WD40-like domain RAB3GAP2_N PF14655.6 KFQ92225.1 - 0.0088 15.3 0.0 0.11 11.7 0.0 2.4 1 1 1 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Cytochrom_D1 PF02239.16 KFQ92225.1 - 0.018 13.6 0.0 0.96 7.9 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain VID27 PF08553.10 KFQ92225.1 - 0.077 12.0 0.3 0.32 10.0 0.0 1.9 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain PD40 PF07676.12 KFQ92225.1 - 0.099 12.6 0.2 26 4.9 0.1 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat ATP_synth_reg PF14960.6 KFQ92226.1 - 1.8e-27 94.6 0.3 2.1e-27 94.4 0.3 1.0 1 0 0 1 1 1 1 ATP synthase regulation DUF1516 PF07457.11 KFQ92226.1 - 0.088 13.0 0.0 0.093 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1516) Suf PF05843.14 KFQ92227.1 - 5.8e-13 49.5 6.0 5.5e-09 36.4 1.2 4.1 1 1 3 4 4 4 3 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KFQ92227.1 - 1.2e-10 41.7 0.1 0.00013 22.4 0.0 3.6 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ92227.1 - 3.2e-09 36.9 6.2 0.01 16.6 0.1 5.5 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 KFQ92227.1 - 9.2e-08 31.6 6.4 0.00054 19.3 0.8 3.3 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ92227.1 - 5.1e-06 27.0 0.1 0.0082 16.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ92227.1 - 4.6e-05 23.6 3.4 0.0051 17.1 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ92227.1 - 0.0045 17.0 5.9 2.1 8.7 0.2 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ92227.1 - 0.0067 16.6 0.8 0.96 9.7 0.5 2.9 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 FAM124 PF15067.6 KFQ92227.1 - 0.014 15.0 0.7 0.42 10.2 0.3 2.4 2 0 0 2 2 2 0 FAM124 family Ras_bdg_2 PF14847.6 KFQ92227.1 - 0.042 14.2 0.8 1.9 8.9 0.1 2.9 2 0 0 2 2 2 0 Ras-binding domain of Byr2 PPR_2 PF13041.6 KFQ92227.1 - 0.18 12.0 0.1 2.4 8.4 0.1 2.7 2 0 0 2 2 2 0 PPR repeat family PPR PF01535.20 KFQ92227.1 - 0.28 11.5 0.9 21 5.7 0.1 3.8 4 1 0 4 4 3 0 PPR repeat TPR_7 PF13176.6 KFQ92227.1 - 2.3 8.4 4.2 2.6 8.3 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Ca_hom_mod PF14798.6 KFQ92228.1 - 1.4e-86 289.8 0.6 1.6e-86 289.5 0.6 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator DUF1218 PF06749.12 KFQ92228.1 - 0.0019 18.7 1.8 0.0087 16.6 0.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1218) DUF996 PF06195.13 KFQ92228.1 - 0.024 14.9 0.2 0.22 11.8 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF996) Ca_hom_mod PF14798.6 KFQ92229.1 - 2.9e-93 311.6 6.0 3.3e-93 311.4 6.0 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator Ca_hom_mod PF14798.6 KFQ92230.1 - 1.9e-96 322.0 11.0 2.3e-96 321.8 11.0 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator Neuralized PF07177.12 KFQ92232.1 - 8.5e-85 282.2 0.0 4.1e-41 140.5 0.0 2.1 2 0 0 2 2 2 2 Neuralized zf-C3HC4_3 PF13920.6 KFQ92232.1 - 7.4e-13 48.1 13.3 7.4e-13 48.1 13.3 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFQ92232.1 - 1.4e-05 24.9 11.6 1.4e-05 24.9 11.6 3.2 4 0 0 4 4 4 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFQ92232.1 - 0.4 10.7 21.5 0.026 14.5 14.6 2.7 3 0 0 3 3 3 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFQ92232.1 - 0.55 10.1 20.0 0.081 12.8 15.0 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SH3_1 PF00018.28 KFQ92233.1 - 7.5e-39 131.1 20.5 4.3e-11 42.2 0.3 5.4 5 0 0 5 5 5 5 SH3 domain SH3_2 PF07653.17 KFQ92233.1 - 9.8e-35 118.0 9.0 1.9e-10 40.2 0.1 5.3 5 0 0 5 5 5 5 Variant SH3 domain SH3_9 PF14604.6 KFQ92233.1 - 1.3e-32 111.4 15.3 4.8e-10 39.1 0.1 5.4 5 0 0 5 5 5 5 Variant SH3 domain SH3_3 PF08239.11 KFQ92233.1 - 9.7e-16 57.8 22.5 0.00077 19.7 0.1 5.6 5 0 0 5 5 5 5 Bacterial SH3 domain DUF1604 PF07713.13 KFQ92233.1 - 0.0059 16.4 10.5 0.93 9.4 0.1 5.5 5 0 0 5 5 5 1 Protein of unknown function (DUF1604) hSH3 PF14603.6 KFQ92233.1 - 0.16 12.4 0.2 3.1 8.3 0.0 3.0 3 0 0 3 3 3 0 Helically-extended SH3 domain SH3_6 PF12913.7 KFQ92233.1 - 0.31 10.6 3.4 1.7 8.3 0.1 2.9 2 0 0 2 2 2 0 SH3 domain (SH3b1 type) PX PF00787.24 KFQ92234.1 - 1.3e-16 60.6 0.1 1.4e-16 60.5 0.1 1.0 1 0 0 1 1 1 1 PX domain STN1_2 PF09170.10 KFQ92235.1 - 3e-70 236.0 0.5 5.7e-70 235.1 0.5 1.5 1 0 0 1 1 1 1 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 tRNA_anti-codon PF01336.25 KFQ92235.1 - 2.5e-09 37.0 0.1 5.1e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Stn1 PF10451.9 KFQ92235.1 - 1.9e-07 30.3 0.7 9.9e-07 28.0 0.2 2.2 1 1 1 2 2 2 1 Telomere regulation protein Stn1 PKK PF12474.8 KFQ92236.1 - 5.2e-78 259.9 101.3 1.4e-41 141.9 42.9 7.9 7 2 0 7 7 7 2 Polo kinase kinase Pkinase PF00069.25 KFQ92236.1 - 5.3e-68 229.2 0.0 5.3e-68 229.2 0.0 3.7 3 1 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ92236.1 - 9e-48 162.8 0.0 9e-48 162.8 0.0 2.9 3 1 0 3 3 3 1 Protein tyrosine kinase APH PF01636.23 KFQ92236.1 - 1.2 9.0 0.0 1.2 9.0 0.0 3.7 3 1 0 3 3 3 0 Phosphotransferase enzyme family Collagen PF01391.18 KFQ92237.1 - 3.8e-61 202.7 395.3 1e-09 38.0 33.3 17.9 9 4 5 14 14 14 12 Collagen triple helix repeat (20 copies) DUF5006 PF16397.5 KFQ92237.1 - 0.012 14.9 0.0 0.018 14.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5006) DUF2868 PF11067.8 KFQ92237.1 - 3 7.3 5.9 6.1 6.3 5.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Mei5 PF10376.9 KFQ92238.1 - 7.6e-57 192.5 3.9 8.7e-57 192.3 3.9 1.0 1 0 0 1 1 1 1 Double-strand recombination repair protein Mei5_like PF17021.5 KFQ92238.1 - 0.0088 16.1 0.1 0.015 15.3 0.1 1.4 1 0 0 1 1 1 1 Putative double-strand recombination repair-like WD40 PF00400.32 KFQ92239.1 - 0.005 17.6 0.2 0.85 10.6 0.0 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat Leuk-A4-hydro_C PF09127.11 KFQ92239.1 - 0.56 10.3 10.6 0.13 12.3 0.7 3.7 4 0 0 4 4 4 0 Leukotriene A4 hydrolase, C-terminal Tmemb_185A PF10269.9 KFQ92240.1 - 0.043 13.5 0.0 0.056 13.1 0.0 1.1 1 0 0 1 1 1 0 Transmembrane Fragile-X-F protein GST_N_3 PF13417.6 KFQ92242.1 - 1.5e-21 76.5 0.0 5.6e-21 74.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFQ92242.1 - 7.9e-16 58.1 0.0 1.7e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFQ92242.1 - 3.1e-13 49.9 0.0 5.2e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFQ92242.1 - 7.5e-09 35.7 0.1 1.3e-08 35.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFQ92242.1 - 2.3e-08 33.9 0.0 4.8e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFQ92242.1 - 1.4e-07 31.6 0.1 2.2e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KFQ92242.1 - 0.00032 21.2 0.0 0.00052 20.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KFQ92242.1 - 0.00061 20.0 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_4 PF17172.4 KFQ92242.1 - 0.052 14.3 0.0 0.12 13.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Mab-21 PF03281.14 KFQ92243.1 - 3.1e-23 82.5 3.0 1.8e-21 76.7 1.1 3.0 2 1 0 2 2 2 1 Mab-21 protein CemA PF03040.14 KFQ92243.1 - 1 9.3 2.8 1.7 8.5 2.8 1.3 1 0 0 1 1 1 0 CemA family Sortilin-Vps10 PF15902.5 KFQ92245.1 - 2.9e-97 326.3 0.4 7.9e-97 324.8 0.0 1.7 2 0 0 2 2 2 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KFQ92245.1 - 8e-37 127.2 6.0 1.3e-36 126.5 6.0 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal PKD PF00801.20 KFQ92245.1 - 3e-16 59.0 2.2 1.5e-09 37.6 0.0 2.4 2 0 0 2 2 2 2 PKD domain BNR PF02012.20 KFQ92245.1 - 0.18 11.9 13.4 1.5 9.2 0.6 5.9 6 0 0 6 6 6 0 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 KFQ92246.1 - 6.7e-104 348.2 0.0 8.7e-104 347.8 0.0 1.1 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KFQ92246.1 - 1.1e-36 126.7 7.3 1.8e-36 126.0 7.3 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal PKD PF00801.20 KFQ92246.1 - 1.3e-12 47.4 3.8 2.1e-08 33.9 0.0 2.4 2 0 0 2 2 2 2 PKD domain BNR PF02012.20 KFQ92246.1 - 0.0062 16.4 11.7 3.5 8.0 0.5 5.9 5 0 0 5 5 5 1 BNR/Asp-box repeat TNFR_16_TM PF18422.1 KFQ92246.1 - 0.42 10.6 1.9 1.1 9.2 1.9 1.7 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Peptidase_M24 PF00557.24 KFQ92247.1 - 1.1e-45 156.0 0.0 1.5e-45 155.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 KFQ92247.1 - 5.2e-45 153.4 0.0 8.2e-45 152.8 0.0 1.3 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 KFQ92247.1 - 1.1e-24 86.3 0.3 7.5e-24 83.6 0.1 2.6 3 0 0 3 3 3 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KFQ92247.1 - 1.2e-14 55.1 0.0 2.6e-12 47.5 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Aldolase_II PF00596.21 KFQ92249.1 - 5.8e-38 130.7 0.0 9.2e-38 130.0 0.0 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF16 PF01519.16 KFQ92249.1 - 1.7 9.2 5.9 7.1 7.2 5.9 2.2 1 1 0 1 1 1 0 Protein of unknown function DUF16 SMN PF06003.12 KFQ92250.1 - 2.5e-17 63.0 5.3 3.1e-17 62.7 3.9 1.9 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 KFQ92250.1 - 0.0001 22.3 0.0 0.00033 20.7 0.0 1.9 1 1 0 1 1 1 1 Tudor domain DSPc PF00782.20 KFQ92252.1 - 2.5e-45 153.6 0.1 3.3e-45 153.2 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFQ92252.1 - 2.1e-05 24.2 0.0 2.7e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KFQ92252.1 - 0.019 15.3 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain CDKN3 PF05706.12 KFQ92252.1 - 0.076 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) SMC_N PF02463.19 KFQ92253.1 - 1.7e-63 214.0 23.5 3.4e-63 213.0 23.5 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KFQ92253.1 - 3.7e-21 75.6 0.0 1.1e-20 74.1 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 KFQ92253.1 - 2.3e-12 47.3 13.0 2.3e-12 47.3 13.0 5.2 2 2 2 4 4 4 2 AAA ATPase domain AAA_21 PF13304.6 KFQ92253.1 - 7.3e-11 42.4 20.6 3.4e-06 27.1 0.0 5.1 5 1 0 6 6 6 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFQ92253.1 - 1e-08 35.9 47.0 1e-08 35.9 47.0 8.0 2 2 2 4 4 4 1 AAA domain AAA_29 PF13555.6 KFQ92253.1 - 0.0041 16.8 0.0 0.0091 15.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Muted PF14942.6 KFQ92253.1 - 0.0065 16.8 11.7 0.0065 16.8 11.7 8.3 2 2 6 8 8 8 1 Organelle biogenesis, Muted-like protein ABC_tran PF00005.27 KFQ92253.1 - 1.4 9.4 0.0 1.4 9.4 0.0 7.1 2 2 2 4 4 4 0 ABC transporter zf-C2H2_jaz PF12171.8 KFQ92254.1 - 0.0015 18.8 0.2 0.0031 17.8 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding RRM_1 PF00076.22 KFQ92254.1 - 0.075 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-met PF12874.7 KFQ92254.1 - 0.078 13.4 0.3 0.18 12.2 0.3 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type YqfD PF06898.11 KFQ92254.1 - 0.11 11.3 0.5 0.18 10.6 0.5 1.3 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD HAP1_N PF04849.13 KFQ92255.1 - 0.012 14.9 1.7 0.015 14.5 1.7 1.3 1 1 0 1 1 1 0 HAP1 N-terminal conserved region zf-U1 PF06220.12 KFQ92255.1 - 0.012 15.4 2.6 0.02 14.7 2.6 1.3 1 0 0 1 1 1 0 U1 zinc finger NACHT_N PF17100.5 KFQ92255.1 - 0.082 12.8 0.1 0.36 10.6 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase zf-C2H2_jaz PF12171.8 KFQ92255.1 - 0.13 12.6 2.9 0.3 11.4 2.9 1.6 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding MA3 PF02847.17 KFQ92256.1 - 8.7e-48 161.0 0.4 9.5e-25 86.8 0.4 2.1 2 0 0 2 2 2 2 MA3 domain HABP4_PAI-RBP1 PF04774.15 KFQ92256.1 - 0.05 14.5 3.3 0.096 13.5 0.0 2.3 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family LRR_8 PF13855.6 KFQ92257.1 - 1.4e-57 191.3 67.8 1.3e-11 44.0 7.1 8.7 4 3 5 10 10 10 9 Leucine rich repeat LRR_4 PF12799.7 KFQ92257.1 - 9.6e-40 133.9 74.3 1.6e-06 28.3 3.6 10.8 4 2 8 13 13 13 13 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFQ92257.1 - 2.6e-12 46.6 36.0 0.0018 17.8 2.0 5.8 2 2 4 6 6 6 5 Leucine-rich repeat LRR_5 PF13306.6 KFQ92257.1 - 1.1e-06 28.7 4.1 0.1 12.6 1.0 4.5 1 1 5 6 6 6 4 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFQ92257.1 - 7.7e-06 25.8 62.7 4.2 8.3 0.7 17.1 18 2 0 18 18 18 2 Leucine Rich Repeat HERV-K_REC PF15695.5 KFQ92257.1 - 0.032 14.3 1.6 2.7 8.1 0.1 3.6 3 0 0 3 3 3 0 Rec (regulator of expression encoded by corf) of HERV-K-113 RsmF_methylt_CI PF17126.5 KFQ92257.1 - 0.25 11.4 1.7 25 5.0 0.0 4.8 4 2 1 6 6 6 0 RsmF rRNA methyltransferase first C-terminal domain SUFU_C PF12470.8 KFQ92257.1 - 0.7 9.9 2.7 0.87 9.6 0.6 2.1 2 0 0 2 2 2 0 Suppressor of Fused Gli/Ci N terminal binding domain 7tm_1 PF00001.21 KFQ92258.1 - 2.8e-78 262.9 0.0 3.6e-78 262.5 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ92258.1 - 4.8e-10 39.2 13.4 3e-06 26.8 5.5 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFQ92258.1 - 2.5e-07 30.7 6.8 8.8e-06 25.7 4.3 2.2 2 0 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFQ92258.1 - 1.5e-05 24.7 12.8 1.5e-05 24.7 12.8 2.3 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx T2SSM PF04612.12 KFQ92258.1 - 0.21 11.6 0.1 0.4 10.7 0.1 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Acyltransferase PF01553.21 KFQ92259.1 - 9.9e-23 80.2 0.0 2.2e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase Zona_pellucida PF00100.23 KFQ92260.1 - 5.8e-34 118.1 8.1 6.9e-34 117.8 8.1 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain AMP-binding PF00501.28 KFQ92261.1 - 7.9e-113 377.2 0.0 1e-112 376.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFQ92261.1 - 0.00028 21.8 0.1 0.001 20.0 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DHHC PF01529.20 KFQ92262.1 - 6.4e-36 123.4 8.4 9.8e-36 122.8 8.4 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase SH3_2 PF07653.17 KFQ92262.1 - 8.8e-09 34.9 0.4 2.9e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KFQ92262.1 - 0.025 14.4 0.0 0.068 13.0 0.0 1.8 2 0 0 2 2 2 0 Variant SH3 domain V-SNARE PF05008.15 KFQ92263.1 - 1.2e-24 86.5 1.6 1.6e-24 86.0 0.2 1.8 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Exonuc_VII_L PF02601.15 KFQ92263.1 - 0.012 15.2 1.0 0.014 15.0 1.0 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Laminin_I PF06008.14 KFQ92263.1 - 0.016 14.9 1.7 0.045 13.4 1.8 1.7 1 1 0 1 1 1 0 Laminin Domain I DegQ PF08181.11 KFQ92263.1 - 0.11 12.6 2.0 0.38 10.9 1.7 1.9 2 0 0 2 2 2 0 DegQ (SacQ) family DUF1664 PF07889.12 KFQ92263.1 - 0.11 12.5 0.3 0.17 11.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CTNNB1_binding PF08347.11 KFQ92264.1 - 7.2e-38 130.8 7.8 7.2e-38 130.8 7.8 2.9 2 1 0 2 2 2 1 N-terminal CTNNB1 binding HMG_box PF00505.19 KFQ92264.1 - 2.4e-22 79.1 1.0 4.7e-22 78.2 1.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFQ92264.1 - 2.2e-08 34.6 2.0 4.7e-08 33.5 2.0 1.5 1 0 0 1 1 1 1 HMG-box domain Trypsin PF00089.26 KFQ92265.1 - 2.4e-68 230.3 0.6 3.2e-68 229.9 0.6 1.2 1 0 0 1 1 1 1 Trypsin Kringle PF00051.18 KFQ92265.1 - 1.8e-20 73.0 4.6 1.8e-20 73.0 4.6 2.0 2 0 0 2 2 2 1 Kringle domain EGF PF00008.27 KFQ92265.1 - 9.3e-15 54.6 26.0 1.2e-08 35.1 7.4 4.5 4 0 0 4 4 4 2 EGF-like domain Trypsin_2 PF13365.6 KFQ92265.1 - 7.9e-05 23.6 0.0 0.00014 22.8 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain hEGF PF12661.7 KFQ92265.1 - 0.002 18.7 15.8 0.0083 16.7 5.5 5.7 6 0 0 6 6 6 2 Human growth factor-like EGF DUF1986 PF09342.11 KFQ92265.1 - 0.0086 16.5 0.1 0.016 15.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) EGF_2 PF07974.13 KFQ92265.1 - 0.023 15.1 11.9 0.023 15.1 11.9 4.9 4 0 0 4 4 4 0 EGF-like domain EGF_3 PF12947.7 KFQ92265.1 - 1.2 9.4 29.1 0.13 12.5 7.3 4.3 2 2 2 4 4 4 0 EGF domain Nebulin PF00880.18 KFQ92266.1 - 8.6e-216 696.4 163.5 1.2e-08 34.7 0.3 43.6 44 0 0 44 44 44 43 Nebulin repeat LIM PF00412.22 KFQ92266.1 - 3.3e-10 40.0 9.6 7.8e-10 38.8 9.6 1.7 1 0 0 1 1 1 1 LIM domain c-SKI_SMAD_bind PF08782.10 KFQ92266.1 - 0.044 14.0 1.1 0.19 12.0 1.1 2.1 1 0 0 1 1 1 0 c-SKI Smad4 binding domain OGG_N PF07934.12 KFQ92266.1 - 0.21 11.7 3.5 0.89 9.7 1.3 3.1 2 1 0 2 2 2 0 8-oxoguanine DNA glycosylase, N-terminal domain ArfA PF03889.13 KFQ92266.1 - 0.37 10.3 4.3 35 4.0 0.0 4.7 5 0 0 5 5 5 0 Alternative ribosome-rescue factor A DUF1510 PF07423.11 KFQ92266.1 - 0.62 10.3 5.5 34 4.7 0.1 4.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1510) YlbE PF14003.6 KFQ92266.1 - 9.7 6.7 8.5 63 4.1 0.3 4.5 4 0 0 4 4 4 0 YlbE-like protein TPR_MLP1_2 PF07926.12 KFQ92268.1 - 0.011 15.8 21.4 0.011 15.8 21.4 9.0 4 1 6 10 10 10 0 TPR/MLP1/MLP2-like protein TUDOR PF00567.24 KFQ92269.1 - 4.5e-123 404.4 5.0 1.3e-34 118.8 0.0 4.4 4 0 0 4 4 4 4 Tudor domain SMN PF06003.12 KFQ92269.1 - 8.8e-18 64.5 0.2 1.8e-05 24.1 0.0 4.3 4 0 0 4 4 4 4 Survival motor neuron protein (SMN) zf-MYND PF01753.18 KFQ92269.1 - 4.6e-10 39.4 13.3 4.6e-10 39.4 13.3 2.6 2 0 0 2 2 2 1 MYND finger Agenet PF05641.12 KFQ92269.1 - 2.5e-07 31.0 0.8 1.3 9.6 0.0 4.7 4 0 0 4 4 4 2 Agenet domain DUF4537 PF15057.6 KFQ92269.1 - 1.5e-06 28.2 0.0 3.1 7.8 0.0 4.5 4 0 0 4 4 4 3 Domain of unknown function (DUF4537) SNase PF00565.17 KFQ92269.1 - 0.0049 17.3 0.3 0.062 13.8 0.0 2.6 3 0 0 3 3 3 1 Staphylococcal nuclease homologue Tudor_4 PF18358.1 KFQ92269.1 - 0.036 13.7 0.7 1.2 8.8 0.0 3.1 3 0 0 3 3 3 0 Histone methyltransferase Tudor domain NitrOD1 PF18549.1 KFQ92269.1 - 0.081 12.9 0.0 14 5.8 0.0 3.3 2 0 0 2 2 2 0 Nitrosopumilus output domain 1 PCB_OB PF17092.5 KFQ92269.1 - 0.11 13.3 0.0 5.5 7.8 0.0 3.0 3 0 0 3 3 3 0 Penicillin-binding protein OB-like domain zf-HIT PF04438.16 KFQ92269.1 - 5 7.1 15.0 0.41 10.6 8.9 2.5 2 0 0 2 2 2 0 HIT zinc finger VWA PF00092.28 KFQ92270.1 - 4.3e-95 316.9 0.0 2.4e-36 125.6 0.0 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 KFQ92270.1 - 7.7e-38 129.4 0.0 6.9e-14 52.4 0.0 3.6 3 0 0 3 3 3 3 von Willebrand factor type A domain EGF PF00008.27 KFQ92270.1 - 1.3e-14 54.1 25.7 2.5e-08 34.1 9.8 2.7 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 KFQ92270.1 - 4.2e-08 33.5 18.6 0.00011 22.7 5.8 3.0 2 0 0 2 2 2 2 Human growth factor-like EGF VWA_3 PF13768.6 KFQ92270.1 - 4.2e-08 33.3 0.0 0.16 11.9 0.0 3.3 3 0 0 3 3 3 3 von Willebrand factor type A domain FMN_red PF03358.15 KFQ92270.1 - 0.098 12.4 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 NADPH-dependent FMN reductase EGF_2 PF07974.13 KFQ92270.1 - 0.17 12.3 29.3 0.99 9.8 9.6 2.7 2 0 0 2 2 2 0 EGF-like domain FXa_inhibition PF14670.6 KFQ92270.1 - 0.42 10.9 18.9 2.8 8.3 5.2 2.9 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site PH PF00169.29 KFQ92271.1 - 2.3e-22 79.5 2.5 3.4e-10 40.4 0.0 2.6 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KFQ92271.1 - 6.2e-07 29.8 8.2 0.0032 17.9 0.6 3.9 2 2 0 2 2 2 2 Pleckstrin homology domain UPF0242 PF06785.11 KFQ92271.1 - 0.019 15.1 7.8 0.056 13.5 7.8 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Takusan PF04822.13 KFQ92271.1 - 0.23 11.4 8.7 0.76 9.7 8.7 1.9 1 0 0 1 1 1 0 Takusan PH_9 PF15410.6 KFQ92271.1 - 0.23 11.8 1.2 15 6.0 0.1 3.6 2 2 0 2 2 2 0 Pleckstrin homology domain DUF4446 PF14584.6 KFQ92271.1 - 2.1 8.3 4.7 5.7 6.9 4.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) AbLIM_anchor PF16182.5 KFQ92272.1 - 2.6e-112 376.4 26.9 2.7e-87 294.0 21.1 2.7 1 1 1 2 2 2 2 Putative adherens-junction anchoring region of AbLIM LIM PF00412.22 KFQ92272.1 - 1.4e-44 150.1 42.3 6.9e-15 55.0 1.7 5.0 4 1 1 5 5 5 4 LIM domain VHP PF02209.19 KFQ92272.1 - 1.3e-15 57.1 1.2 2.2e-15 56.4 0.6 1.7 2 0 0 2 2 2 1 Villin headpiece domain RAI16-like PF10257.9 KFQ92273.1 - 5.3e-141 469.7 3.0 6.9e-141 469.3 3.0 1.1 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein TruB_N PF01509.18 KFQ92274.1 - 1.5e-48 165.0 0.0 2.1e-48 164.4 0.0 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KFQ92274.1 - 2.5e-08 33.9 0.0 5e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Kelch_5 PF13854.6 KFQ92275.1 - 1.5e-26 91.9 18.1 4.5e-08 32.9 0.0 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KFQ92275.1 - 2.1e-20 72.4 6.0 4e-05 23.5 0.1 6.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 KFQ92275.1 - 4.3e-20 71.0 15.3 0.00012 21.6 0.2 6.7 7 0 0 7 7 7 5 Kelch motif PSI PF01437.25 KFQ92275.1 - 4e-18 65.7 54.1 1.1e-12 48.3 9.8 8.3 7 1 0 7 7 6 5 Plexin repeat Kelch_6 PF13964.6 KFQ92275.1 - 9.4e-17 60.6 15.0 3.7e-05 23.8 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Lectin_C PF00059.21 KFQ92275.1 - 8.1e-16 58.7 0.1 8.1e-16 58.7 0.1 3.4 3 1 0 3 3 1 1 Lectin C-type domain Kelch_3 PF13415.6 KFQ92275.1 - 3.2e-13 49.6 9.7 0.00051 20.3 0.0 6.7 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KFQ92275.1 - 8.2e-12 44.6 8.4 0.022 14.7 0.0 5.5 5 0 0 5 5 5 3 Kelch motif CUB PF00431.20 KFQ92275.1 - 2.5e-11 43.9 0.0 7.5e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 CUB domain EGF_2 PF07974.13 KFQ92275.1 - 8.9e-05 22.8 10.2 8.9e-05 22.8 10.2 8.6 5 2 0 5 5 2 2 EGF-like domain Laminin_EGF PF00053.24 KFQ92275.1 - 0.00011 22.3 18.3 0.00011 22.3 18.3 8.5 5 3 2 7 7 4 2 Laminin EGF domain PSI_integrin PF17205.3 KFQ92275.1 - 0.0013 18.4 7.7 0.0013 18.4 7.7 6.7 7 0 0 7 7 4 2 Integrin plexin domain GDNF PF02351.16 KFQ92276.1 - 9.3e-40 135.5 49.9 3.7e-21 75.9 8.0 3.1 3 0 0 3 3 3 3 GDNF/GAS1 domain Rab5-bind PF09311.11 KFQ92277.1 - 0.0014 18.1 16.1 0.0014 18.1 16.1 2.2 1 1 1 2 2 2 2 Rabaptin-like protein ATG16 PF08614.11 KFQ92277.1 - 0.018 15.3 21.0 0.047 13.9 21.0 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Syntaxin-6_N PF09177.11 KFQ92277.1 - 0.25 11.9 13.9 0.043 14.4 8.4 2.4 2 1 1 3 3 3 0 Syntaxin 6, N-terminal HAUS-augmin3 PF14932.6 KFQ92277.1 - 1.7 8.2 25.9 0.16 11.5 13.6 2.4 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 USP8_interact PF08941.10 KFQ92277.1 - 2.1 8.1 8.9 0.43 10.4 2.1 2.4 1 1 0 2 2 2 0 USP8 interacting Spc7 PF08317.11 KFQ92277.1 - 2.9 6.7 28.3 0.53 9.1 17.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KFQ92277.1 - 3 7.9 33.7 0.26 11.3 24.6 2.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc24 PF08286.11 KFQ92277.1 - 3.9 7.8 25.4 7.7 6.8 6.3 3.3 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 DUF3450 PF11932.8 KFQ92277.1 - 4.3 6.6 16.0 0.52 9.6 10.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Lipase PF00151.19 KFQ92278.1 - 6.6e-58 196.6 0.1 8.1e-58 196.3 0.1 1.1 1 0 0 1 1 1 1 Lipase PLAT PF01477.23 KFQ92278.1 - 2.8e-05 24.6 0.1 4.9e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain Lipase PF00151.19 KFQ92279.1 - 7.6e-71 239.1 0.0 9.5e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 Lipase PLAT PF01477.23 KFQ92279.1 - 2e-08 34.8 0.3 3.7e-08 33.9 0.3 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain HSP70 PF00012.20 KFQ92280.1 - 2.1e-06 26.2 0.0 0.04 12.1 0.0 3.2 3 0 0 3 3 3 3 Hsp70 protein GA-like PF17573.2 KFQ92280.1 - 0.058 13.3 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 GA-like domain FGGY_C PF02782.16 KFQ92280.1 - 0.16 11.6 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Enolase_C PF00113.22 KFQ92281.1 - 3.5e-26 92.2 0.0 4.5e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KFQ92281.1 - 6.3e-15 55.5 0.2 2.2e-09 37.6 0.1 2.3 2 0 0 2 2 2 2 Enolase, N-terminal domain DUF4894 PF16235.5 KFQ92282.1 - 0.42 11.0 3.9 1.5 9.2 3.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4894) Ion_trans_2 PF07885.16 KFQ92283.1 - 7.2e-30 102.8 21.4 3.2e-18 65.5 4.0 2.9 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KFQ92283.1 - 0.00034 19.9 15.6 0.029 13.6 4.3 2.4 2 1 0 2 2 2 2 Ion transport protein MFS_1 PF07690.16 KFQ92284.1 - 7.3e-45 153.4 38.7 1.3e-37 129.5 28.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFQ92284.1 - 5.7e-11 41.9 22.5 5.5e-09 35.4 1.4 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter LacY_symp PF01306.19 KFQ92284.1 - 0.0025 16.7 7.7 0.0025 16.7 7.7 2.8 2 1 0 2 2 2 1 LacY proton/sugar symporter SAYSvFN PF10260.9 KFQ92284.1 - 0.1 12.5 0.2 0.52 10.3 0.2 2.3 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) S_4TM PF18159.1 KFQ92284.1 - 0.22 10.8 0.2 0.49 9.6 0.2 1.6 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain PDZ_6 PF17820.1 KFQ92285.1 - 2.1e-11 43.5 0.1 4.3e-11 42.5 0.1 1.6 1 0 0 1 1 1 1 PDZ domain C1_1 PF00130.22 KFQ92285.1 - 1.9e-08 34.1 13.5 4e-08 33.0 13.5 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PDZ_2 PF13180.6 KFQ92285.1 - 3e-08 33.9 0.1 7.6e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFQ92285.1 - 2.5e-07 30.9 0.1 6.5e-07 29.6 0.1 1.7 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KFQ92285.1 - 0.0038 17.5 0.0 0.0073 16.6 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain MMM1 PF10296.9 KFQ92285.1 - 0.067 12.2 0.0 0.22 10.5 0.0 1.8 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 Homeodomain PF00046.29 KFQ92286.1 - 7.8e-22 76.9 2.6 1.4e-21 76.0 2.6 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ92286.1 - 0.018 14.9 0.0 0.06 13.3 0.0 1.9 1 0 0 1 1 1 0 Homeobox KN domain DUF874 PF05917.11 KFQ92286.1 - 0.056 12.5 1.7 0.097 11.7 1.7 1.3 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) C2 PF00168.30 KFQ92287.1 - 1.1e-19 70.6 0.2 6.4e-19 68.2 0.0 2.3 2 0 0 2 2 2 1 C2 domain RBD-FIP PF09457.10 KFQ92287.1 - 1.7e-16 59.8 3.0 3.7e-16 58.8 3.0 1.6 1 0 0 1 1 1 1 FIP domain DDHD PF02862.17 KFQ92288.1 - 0.099 12.8 3.1 0.1 12.7 3.1 1.2 1 0 0 1 1 1 0 DDHD domain Peptidase_A21 PF03566.13 KFQ92288.1 - 0.17 10.1 1.9 0.21 9.8 1.9 1.1 1 0 0 1 1 1 0 Peptidase family A21 Jak1_Phl PF17887.1 KFQ92288.1 - 0.86 9.6 7.2 1.8 8.6 7.2 1.5 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain Presenilin PF01080.17 KFQ92288.1 - 9.5 4.9 6.2 9.6 4.8 6.2 1.1 1 0 0 1 1 1 0 Presenilin Cullin PF00888.22 KFQ92289.1 - 6.9e-14 51.4 0.0 7.5e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Cullin family Herpes_pp85 PF04637.12 KFQ92289.1 - 0.0044 15.5 0.0 0.0066 14.9 0.0 1.3 1 0 0 1 1 1 1 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DNA_repr_REX1B PF14966.6 KFQ92289.1 - 0.015 15.9 0.1 0.054 14.2 0.1 1.9 1 1 1 2 2 2 0 DNA repair REX1-B PCI PF01399.27 KFQ92290.1 - 9.9e-20 71.0 0.1 9.9e-20 71.0 0.1 4.3 5 0 0 5 5 5 1 PCI domain Avl9 PF09794.9 KFQ92291.1 - 5e-11 41.9 0.1 5.9e-07 28.5 0.0 2.1 1 1 1 2 2 2 2 Transport protein Avl9 SPA PF08616.10 KFQ92291.1 - 6.9e-11 42.1 0.0 1.4e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis DUF2347 PF09804.9 KFQ92291.1 - 1.6e-08 34.5 0.1 3.6e-08 33.4 0.1 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Toxin-deaminase PF14424.6 KFQ92291.1 - 0.0099 16.0 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 The BURPS668_1122 family of deaminases DUF4373 PF14297.6 KFQ92291.1 - 0.078 13.8 0.1 0.57 11.0 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4373) Mtc PF03820.17 KFQ92292.1 - 7.8e-55 186.1 0.1 8.6e-55 186.0 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier DUF3574 PF12098.8 KFQ92292.1 - 0.051 13.4 0.1 7.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) SSF PF00474.17 KFQ92292.1 - 0.055 12.3 2.2 0.32 9.8 0.3 2.0 2 0 0 2 2 2 0 Sodium:solute symporter family RE_HaeIII PF09556.10 KFQ92292.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 HaeIII restriction endonuclease AhpC-TSA PF00578.21 KFQ92293.1 - 1.6e-35 121.8 0.0 2.2e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFQ92293.1 - 9.6e-16 57.8 0.0 1.2e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KFQ92293.1 - 3.3e-14 52.4 0.1 5.4e-14 51.8 0.1 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 KFQ92293.1 - 0.024 14.5 0.1 0.05 13.5 0.1 1.4 1 0 0 1 1 1 0 SCO1/SenC Endothelin PF00322.17 KFQ92293.1 - 0.14 11.8 0.6 0.27 10.9 0.6 1.6 1 0 0 1 1 1 0 Endothelin family Pkinase PF00069.25 KFQ92294.1 - 2.2e-65 220.6 0.0 3.1e-65 220.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ92294.1 - 6.8e-34 117.3 0.0 1e-33 116.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 KFQ92294.1 - 4e-23 81.9 0.2 1.1e-22 80.5 0.0 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain Kinase-like PF14531.6 KFQ92294.1 - 6.2e-05 22.5 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFQ92294.1 - 0.0013 17.6 0.0 0.0038 16.1 0.0 1.6 1 1 0 2 2 2 1 Fungal protein kinase RGS PF00615.19 KFQ92297.1 - 3.9e-33 114.2 5.2 3.9e-33 114.2 5.2 1.5 2 0 0 2 2 2 1 Regulator of G protein signaling domain RGS-like PF09128.11 KFQ92297.1 - 8.5e-05 22.3 0.1 0.00013 21.8 0.1 1.3 1 1 0 1 1 1 1 Regulator of G protein signalling-like domain RRM_1 PF00076.22 KFQ92298.1 - 4.3e-60 199.5 0.0 1.2e-21 76.3 0.0 4.2 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFQ92298.1 - 4.6e-09 36.0 0.0 5.1e-05 23.0 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 KFQ92298.1 - 7e-08 32.5 0.2 0.26 11.4 0.0 4.4 3 1 0 3 3 3 3 RNA recognition motif Nup35_RRM_2 PF14605.6 KFQ92298.1 - 8.1e-05 22.5 0.3 0.15 12.1 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Calcipressin PF04847.12 KFQ92298.1 - 0.00091 19.0 0.0 0.39 10.4 0.0 2.6 3 0 0 3 3 3 2 Calcipressin Nup35_RRM PF05172.13 KFQ92298.1 - 0.00093 19.1 0.2 0.36 10.8 0.2 3.5 1 1 1 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KFQ92298.1 - 0.0098 15.9 0.0 12 6.0 0.0 3.2 3 0 0 3 3 3 1 RNA binding motif DbpA PF03880.15 KFQ92298.1 - 0.15 12.1 0.0 4 7.5 0.0 2.8 3 0 0 3 3 3 0 DbpA RNA binding domain BAG PF02179.16 KFQ92300.1 - 1.9e-18 66.7 4.6 3.2e-18 65.9 4.6 1.4 1 0 0 1 1 1 1 BAG domain Syja_N PF02383.18 KFQ92301.1 - 1.3e-98 330.3 0.6 2.3e-98 329.4 0.6 1.4 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 KFQ92301.1 - 3.9e-23 81.3 0.0 2.1e-22 79.0 0.0 2.3 2 0 0 2 2 2 1 Inositol phosphatase HSM3_C PF18794.1 KFQ92301.1 - 0.034 13.7 1.0 0.92 9.1 0.1 2.8 3 0 0 3 3 3 0 DNA mismatch repair protein HSM3, C terminal domain MCM_bind PF09739.9 KFQ92302.1 - 2.4e-235 782.5 0.0 2.7e-235 782.3 0.0 1.0 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor PAP2 PF01569.21 KFQ92303.1 - 1.7e-28 99.1 0.9 1.7e-28 99.1 0.9 1.5 2 0 0 2 2 2 1 PAP2 superfamily Bax1-I PF01027.20 KFQ92303.1 - 0.071 12.9 0.8 2.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 PAP2_3 PF14378.6 KFQ92303.1 - 0.91 9.2 6.4 33 4.1 6.4 2.6 1 1 0 1 1 1 0 PAP2 superfamily ANAPC4_WD40 PF12894.7 KFQ92304.1 - 2.5e-09 37.3 3.9 0.58 10.5 0.0 7.0 5 1 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 KFQ92304.1 - 0.0011 18.8 0.2 0.94 9.5 0.0 3.2 2 0 0 2 2 2 2 PQQ enzyme repeat RAB3GAP2_N PF14655.6 KFQ92304.1 - 0.0064 15.8 0.1 0.051 12.8 0.0 2.4 3 0 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40 PF00400.32 KFQ92304.1 - 0.018 15.9 12.2 7.1 7.7 0.2 6.3 7 0 0 7 7 7 0 WD domain, G-beta repeat PQQ_2 PF13360.6 KFQ92304.1 - 0.061 12.9 0.3 0.72 9.4 0.0 2.9 3 0 0 3 3 3 0 PQQ-like domain Ser_hydrolase PF06821.13 KFQ92304.1 - 0.089 12.6 0.2 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 Serine hydrolase VPS9 PF02204.18 KFQ92305.1 - 7.4e-23 80.7 0.1 1.6e-22 79.6 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain RA PF00788.23 KFQ92305.1 - 1.6e-12 47.9 0.1 4.2e-12 46.5 0.1 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH2 PF00017.24 KFQ92305.1 - 0.0019 18.2 0.0 0.0077 16.3 0.0 2.1 2 0 0 2 2 2 1 SH2 domain FERM_f0 PF16511.5 KFQ92305.1 - 0.0085 16.4 0.0 0.062 13.6 0.0 2.3 2 0 0 2 2 2 1 N-terminal or F0 domain of Talin-head FERM VRP3 PF03536.15 KFQ92305.1 - 0.025 14.1 0.1 0.046 13.2 0.1 1.4 1 0 0 1 1 1 0 Salmonella virulence-associated 28kDa protein RelB PF04221.12 KFQ92305.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 RelB antitoxin Na_Ca_ex PF01699.24 KFQ92306.1 - 2.3e-58 196.5 40.4 4.6e-30 104.6 14.7 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein SPC25 PF06703.11 KFQ92306.1 - 0.0036 17.1 2.8 0.019 14.8 0.1 2.6 2 0 0 2 2 2 1 Microsomal signal peptidase 25 kDa subunit (SPC25) CENP-B_dimeris PF09026.10 KFQ92306.1 - 0.017 15.5 10.3 0.039 14.3 10.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BUD22 PF09073.10 KFQ92306.1 - 0.022 14.1 1.0 0.029 13.7 1.0 1.1 1 0 0 1 1 1 0 BUD22 RXT2_N PF08595.11 KFQ92306.1 - 0.034 14.2 2.3 0.058 13.4 2.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal RNA_pol_3_Rpc31 PF11705.8 KFQ92306.1 - 0.061 13.6 8.2 0.09 13.0 8.2 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PPP4R2 PF09184.11 KFQ92306.1 - 0.13 11.8 5.4 0.19 11.3 5.4 1.2 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 KFQ92306.1 - 0.14 11.4 8.3 0.22 10.8 8.3 1.2 1 0 0 1 1 1 0 NOA36 protein DUF3449 PF11931.8 KFQ92306.1 - 0.16 11.7 1.6 0.29 10.9 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Cwf_Cwc_15 PF04889.12 KFQ92306.1 - 0.27 10.9 7.5 0.4 10.4 7.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein p53-inducible11 PF14936.6 KFQ92306.1 - 1.9 8.5 7.2 0.56 10.2 3.4 2.0 2 0 0 2 2 2 0 Tumour protein p53-inducible protein 11 WRNPLPNID PF15017.6 KFQ92306.1 - 2.2 9.2 11.3 4.3 8.3 11.3 1.5 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box Astro_capsid_p PF12226.8 KFQ92306.1 - 3.9 6.5 7.5 1.6 7.8 5.3 1.4 2 0 0 2 2 2 0 Turkey astrovirus capsid protein FAM176 PF14851.6 KFQ92306.1 - 5.4 6.7 6.7 19 4.9 6.2 2.0 2 0 0 2 2 2 0 FAM176 family DNA_pol_phi PF04931.13 KFQ92306.1 - 6.1 4.8 14.9 9 4.3 14.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KFQ92306.1 - 7.8 4.6 10.7 11 4.1 10.7 1.1 1 0 0 1 1 1 0 Nop14-like family Ac76 PF05814.11 KFQ92306.1 - 7.9 6.6 8.9 0.77 9.8 1.6 2.5 2 0 0 2 2 2 0 Orf76 (Ac76) TRAP_alpha PF03896.16 KFQ92306.1 - 8.1 5.6 6.6 2.8 7.0 3.8 1.6 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit HAT PF02184.16 KFQ92307.1 - 1.2e-36 124.4 71.8 7.3e-16 57.8 1.1 14.6 13 2 0 13 13 13 7 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 KFQ92307.1 - 2.3e-15 55.9 22.2 0.19 12.6 0.4 11.1 7 3 5 12 12 11 5 Tetratricopeptide repeat Suf PF05843.14 KFQ92307.1 - 3.3e-10 40.4 41.5 0.00031 20.8 6.5 6.0 2 1 3 5 5 5 4 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KFQ92307.1 - 8.2e-09 35.9 5.5 0.0099 16.4 0.0 7.5 7 1 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ92307.1 - 2.6e-07 30.6 9.0 0.0014 18.9 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ92307.1 - 1.8e-06 28.4 1.5 5.9 7.6 0.0 6.5 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ92307.1 - 0.0006 19.8 8.0 5.5 7.5 0.0 6.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ92307.1 - 0.0015 18.8 8.3 6.1 7.2 0.0 5.8 5 1 1 6 6 6 2 Tetratricopeptide repeat NRDE-2 PF08424.10 KFQ92307.1 - 0.0042 16.3 33.8 0.0055 15.9 3.3 6.1 1 1 3 5 5 5 4 NRDE-2, necessary for RNA interference U3_assoc_6 PF08640.11 KFQ92307.1 - 0.01 15.9 1.8 0.01 15.9 1.8 6.4 5 3 2 7 7 7 0 U3 small nucleolar RNA-associated protein 6 Mad3_BUB1_I PF08311.12 KFQ92307.1 - 0.041 13.9 34.8 0.26 11.3 3.3 7.5 5 4 0 5 5 5 0 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 KFQ92307.1 - 0.44 10.8 25.2 2.2 8.6 0.3 8.6 12 0 0 12 12 10 0 Tetratricopeptide repeat DUF4821 PF16092.5 KFQ92308.1 - 3.5e-103 344.8 1.9 1.3e-93 313.4 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4821) Pyr_redox_2 PF07992.14 KFQ92308.1 - 0.00014 21.2 0.0 0.0019 17.5 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFQ92308.1 - 0.05 14.2 0.0 3.9 8.1 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CHASE8 PF17152.4 KFQ92308.1 - 0.066 13.5 0.0 0.21 11.8 0.0 1.8 2 0 0 2 2 2 0 Periplasmic sensor domain XRN_M PF17846.1 KFQ92309.1 - 3.2e-167 557.0 0.0 4.3e-167 556.6 0.0 1.2 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KFQ92309.1 - 3.5e-94 314.8 0.0 6.9e-94 313.8 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Forkhead PF00250.18 KFQ92310.1 - 9.2e-39 131.6 0.2 1.5e-38 131.0 0.2 1.3 1 0 0 1 1 1 1 Forkhead domain Forkhead_N PF08430.12 KFQ92310.1 - 2.8e-25 89.5 45.6 4.6e-25 88.8 45.6 1.3 1 0 0 1 1 1 1 Forkhead N-terminal region 7tm_1 PF00001.21 KFQ92311.1 - 1.5e-62 211.3 11.5 1.7e-62 211.1 11.5 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ92311.1 - 8.2e-16 58.2 3.6 9.7e-16 57.9 3.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFQ92311.1 - 1.1e-09 38.3 2.3 1.1e-09 38.3 2.3 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 KFQ92311.1 - 0.00044 19.6 7.2 0.0035 16.7 0.1 2.5 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 KFQ92311.1 - 0.00054 19.8 8.2 0.0015 18.3 8.2 1.7 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srv PF10323.9 KFQ92311.1 - 0.0028 17.1 5.5 0.0036 16.7 4.1 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv zf-H2C2_2 PF13465.6 KFQ92312.1 - 8.4e-74 241.0 82.2 2.6e-09 37.1 0.7 11.8 12 0 0 12 12 12 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ92312.1 - 1.6e-47 157.4 93.6 2.1e-06 27.9 0.7 12.2 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ92312.1 - 2.8e-40 133.5 88.9 0.00032 21.3 0.5 12.1 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ92312.1 - 7.3e-18 64.4 45.8 0.034 14.5 0.0 11.8 12 0 0 12 12 12 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFQ92312.1 - 2.9e-17 62.2 91.7 0.0066 16.4 3.0 12.6 12 2 0 12 12 12 8 C2H2-type zinc finger zf-met PF12874.7 KFQ92312.1 - 1e-16 60.7 65.2 0.0074 16.7 0.7 11.9 12 0 0 12 12 12 8 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFQ92312.1 - 2.9e-16 58.9 71.2 0.0004 20.1 0.5 12.0 12 1 0 12 12 12 8 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 KFQ92312.1 - 7.2e-06 26.7 39.3 0.23 12.2 1.2 6.2 3 2 3 7 7 7 3 zinc-ribbon family Zn-ribbon_8 PF09723.10 KFQ92312.1 - 8.6e-06 25.8 62.2 0.18 12.0 3.5 9.2 3 3 8 11 11 11 7 Zinc ribbon domain DUF3268 PF11672.8 KFQ92312.1 - 7e-05 23.1 38.5 0.24 11.7 0.4 6.5 4 2 4 8 8 8 5 zinc-finger-containing domain zf_UBZ PF18439.1 KFQ92312.1 - 8.6e-05 22.1 48.8 0.56 9.8 0.1 11.0 12 0 0 12 12 12 5 Ubiquitin-Binding Zinc Finger BolA PF01722.18 KFQ92312.1 - 0.00028 21.1 12.0 2.6 8.4 0.5 5.7 3 2 3 6 6 5 2 BolA-like protein ADK_lid PF05191.14 KFQ92312.1 - 0.00041 20.3 30.2 3.5 7.7 0.3 8.3 6 3 1 7 7 7 3 Adenylate kinase, active site lid zf-H2C2_5 PF13909.6 KFQ92312.1 - 0.05 13.4 0.1 0.05 13.4 0.1 13.3 13 4 0 13 13 10 0 C2H2-type zinc-finger domain zf-trcl PF13451.6 KFQ92312.1 - 0.17 11.8 53.0 5.9 6.9 0.2 10.8 11 0 0 11 11 11 0 Probable zinc-ribbon domain zf_ZIC PF18366.1 KFQ92312.1 - 0.17 12.0 0.4 0.17 12.0 0.4 6.5 7 2 2 9 9 9 0 Zic proteins zinc finger domain zf-C2H2_3rep PF18868.1 KFQ92312.1 - 0.57 10.9 40.1 8.9 7.0 6.2 8.5 1 1 7 8 8 8 0 Zinc finger C2H2-type, 3 repeats Baculo_IE-1 PF05290.11 KFQ92312.1 - 0.61 10.0 21.9 9.8 6.1 0.1 5.4 3 2 2 5 5 5 0 Baculovirus immediate-early protein (IE-0) GATA PF00320.27 KFQ92312.1 - 0.96 9.1 30.3 1.2 8.8 1.0 7.7 6 3 0 6 6 6 0 GATA zinc finger Ta0938 PF11494.8 KFQ92312.1 - 1.2 9.5 26.3 1.4 9.2 1.0 5.7 3 2 4 7 7 7 0 Ta0938 HypA PF01155.19 KFQ92312.1 - 3.3 7.8 45.7 13 5.8 7.2 6.9 1 1 4 5 5 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA IBD PF10416.9 KFQ92312.1 - 5.3 7.1 6.3 58 3.7 0.1 4.1 3 1 1 4 4 4 0 Transcription-initiator DNA-binding domain IBD SNAP PF14938.6 KFQ92313.1 - 6.2e-99 331.0 22.8 7.1e-99 330.8 22.8 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KFQ92313.1 - 1.5e-06 28.4 16.5 0.00056 20.1 0.3 4.5 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ92313.1 - 0.00029 20.7 11.1 0.06 13.4 0.0 5.6 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFQ92313.1 - 0.00046 20.7 11.1 2.3 9.0 0.3 5.7 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ92313.1 - 0.0028 18.3 4.8 16 6.7 0.0 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ92313.1 - 0.013 15.5 20.8 1.8 8.9 0.1 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ92313.1 - 0.07 13.0 7.6 2.6 8.0 0.0 4.4 3 1 2 5 5 5 0 Tetratricopeptide repeat NSF PF02071.20 KFQ92313.1 - 0.097 13.4 39.0 0.55 11.2 2.7 8.7 8 1 1 9 9 8 0 Aromatic-di-Alanine (AdAR) repeat TPR_8 PF13181.6 KFQ92313.1 - 0.22 11.8 23.2 2.7 8.4 0.7 6.4 6 2 1 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ92313.1 - 0.52 11.0 8.8 8.7 7.1 2.7 4.1 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ92313.1 - 1.9 8.2 17.4 3.8 7.3 0.4 5.1 4 1 1 5 5 5 0 TPR repeat Sel1 PF08238.12 KFQ92313.1 - 4.9 8.0 11.3 2.6 8.9 0.3 4.4 5 0 0 5 5 5 0 Sel1 repeat TPR_1 PF00515.28 KFQ92313.1 - 7.5 6.6 22.6 3.3 7.7 1.0 5.1 5 1 0 5 5 4 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 KFQ92314.1 - 1.3e-91 306.5 0.0 1.7e-91 306.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ92314.1 - 6.3e-38 130.6 0.0 9e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 KFQ92314.1 - 1.3e-17 63.9 1.0 1e-07 32.1 0.3 2.7 2 0 0 2 2 2 2 Fibronectin type III domain Ig_2 PF13895.6 KFQ92314.1 - 6.1e-14 52.1 0.1 1.8e-06 28.2 0.1 2.8 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 KFQ92314.1 - 1.4e-13 51.2 0.7 2.5e-06 28.0 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFQ92314.1 - 6.8e-13 48.5 0.0 2e-05 24.6 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.25 KFQ92314.1 - 4.6e-11 42.7 0.0 1e-05 25.6 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFQ92314.1 - 6.1e-05 23.2 0.4 1 9.6 0.0 3.8 3 0 0 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFQ92314.1 - 0.0038 17.3 0.1 0.65 10.1 0.0 3.1 2 1 1 3 3 3 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFQ92314.1 - 0.051 13.1 0.3 0.21 11.2 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin domain APH PF01636.23 KFQ92314.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KFQ92314.1 - 0.11 11.7 0.0 0.3 10.4 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Mad3_BUB1_I PF08311.12 KFQ92315.1 - 8.5e-37 125.9 0.1 3.2e-36 124.0 0.0 2.1 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 KFQ92315.1 - 1.2e-15 57.6 0.0 2.1e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ92315.1 - 7.4e-07 28.7 0.0 1.1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 KFQ92315.1 - 0.072 13.2 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein Pkinase_fungal PF17667.1 KFQ92315.1 - 0.09 11.5 0.9 0.21 10.3 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase Ion_trans PF00520.31 KFQ92316.1 - 1.6e-11 43.9 8.1 2.3e-11 43.4 8.1 1.3 1 0 0 1 1 1 1 Ion transport protein DUF5313 PF17240.2 KFQ92316.1 - 0.11 13.0 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5313) DUF1240 PF06836.12 KFQ92316.1 - 0.21 12.2 4.4 0.089 13.3 1.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) DUF4083 PF13314.6 KFQ92316.1 - 1.2 9.1 6.6 0.11 12.5 1.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) SurA_N_2 PF13623.6 KFQ92316.1 - 7.1 6.5 9.1 5.3 6.9 0.4 2.5 1 1 1 2 2 2 0 SurA N-terminal domain Ion_trans PF00520.31 KFQ92317.1 - 7.4e-18 64.7 25.5 9.9e-18 64.2 25.5 1.1 1 0 0 1 1 1 1 Ion transport protein MARVEL PF01284.23 KFQ92318.1 - 1.4e-09 38.1 11.8 1.7e-09 37.9 11.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF4231 PF14015.6 KFQ92318.1 - 3.4 8.2 7.6 14 6.2 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) Ank_2 PF12796.7 KFQ92319.1 - 5.7e-52 174.2 0.0 2e-18 66.7 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ92319.1 - 1e-46 156.7 0.9 4.8e-11 42.9 0.1 6.4 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ92319.1 - 4.9e-37 121.7 1.5 0.00048 20.4 0.0 9.6 9 0 0 9 9 9 8 Ankyrin repeat Ank PF00023.30 KFQ92319.1 - 6.7e-37 124.4 3.3 5.5e-05 23.4 0.0 9.3 8 1 1 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 KFQ92319.1 - 2.2e-33 113.9 1.8 6.1e-07 29.6 0.1 8.2 1 1 8 9 9 9 8 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFQ92319.1 - 3.6e-10 40.0 4.0 3.6e-10 40.0 4.0 1.8 2 0 0 2 2 2 1 SOCS box DUF3447 PF11929.8 KFQ92319.1 - 0.014 15.4 1.6 0.7 9.9 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) ChaC PF04752.12 KFQ92320.1 - 3.5e-41 141.2 0.0 4e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 KFQ92320.1 - 0.035 14.7 0.0 0.046 14.3 0.0 1.2 1 0 0 1 1 1 0 Gamma-glutamyl cyclotransferase, AIG2-like LRR_8 PF13855.6 KFQ92321.1 - 4.2e-36 122.5 36.6 3.1e-09 36.4 0.2 9.4 3 2 7 10 10 10 8 Leucine rich repeat LRR_4 PF12799.7 KFQ92321.1 - 9.5e-25 86.3 58.7 2.8e-05 24.4 0.4 10.9 10 2 3 13 13 13 9 Leucine Rich repeats (2 copies) TIR PF01582.20 KFQ92321.1 - 9.8e-23 80.8 0.1 1.7e-22 80.1 0.1 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 KFQ92321.1 - 3.7e-18 66.2 0.0 8.7e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.33 KFQ92321.1 - 4.9e-07 29.4 40.1 1.4 9.8 0.0 14.2 16 3 0 16 16 16 3 Leucine Rich Repeat LRR_9 PF14580.6 KFQ92321.1 - 5.9e-06 25.9 11.7 0.053 13.0 0.6 4.5 3 1 1 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 KFQ92321.1 - 0.0001 22.1 35.0 1.3 9.3 0.0 11.5 13 0 0 13 13 13 4 Leucine Rich repeat Acylphosphatase PF00708.18 KFQ92322.1 - 9.9e-16 57.9 0.0 1.1e-15 57.7 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase WD40 PF00400.32 KFQ92323.1 - 1.1e-67 222.2 86.8 7.2e-05 23.5 0.0 28.3 31 0 0 31 31 31 13 WD domain, G-beta repeat HELP PF03451.14 KFQ92323.1 - 4.6e-57 189.8 3.0 2.4e-20 72.2 0.1 3.4 3 0 0 3 3 3 3 HELP motif ANAPC4_WD40 PF12894.7 KFQ92323.1 - 2e-38 130.6 11.2 1.4e-07 31.7 0.0 13.3 9 4 4 13 13 13 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFQ92323.1 - 7e-12 45.0 1.1 0.014 14.3 0.0 7.8 5 3 3 8 8 8 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KFQ92323.1 - 5e-07 28.6 8.4 0.11 11.1 0.0 6.6 6 1 0 6 6 6 2 Cytochrome D1 heme domain WD40_like PF17005.5 KFQ92323.1 - 1.2e-06 28.0 2.3 1.2 8.4 0.0 7.3 8 1 0 8 8 8 2 WD40-like domain Frtz PF11768.8 KFQ92323.1 - 2.3e-05 22.9 0.0 0.014 13.8 0.0 4.0 3 1 1 4 4 4 1 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 KFQ92323.1 - 2.4e-05 24.1 0.5 49 4.0 0.0 6.9 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 KFQ92323.1 - 0.00011 21.1 0.0 0.28 9.9 0.0 4.2 4 0 0 4 4 4 1 Nup133 N terminal like Coatomer_WDAD PF04053.14 KFQ92323.1 - 0.0038 16.3 0.2 8.8 5.2 0.0 4.9 5 2 1 6 6 6 2 Coatomer WD associated region Nup160 PF11715.8 KFQ92323.1 - 0.022 13.4 0.5 35 2.9 0.1 4.3 4 1 1 5 5 5 0 Nucleoporin Nup120/160 Nbas_N PF15492.6 KFQ92323.1 - 0.024 14.0 0.1 17 4.6 0.0 4.5 5 1 1 6 6 6 0 Neuroblastoma-amplified sequence, N terminal PSII_BNR PF14870.6 KFQ92323.1 - 0.17 11.1 2.1 5.1 6.3 0.0 3.3 4 0 0 4 4 4 0 Photosynthesis system II assembly factor YCF48 ubiquitin PF00240.23 KFQ92324.1 - 7.7e-35 118.5 0.6 1.2e-34 117.8 0.3 1.5 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 KFQ92324.1 - 2.9e-28 97.8 4.1 5.8e-28 96.8 4.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.8 KFQ92324.1 - 6.5e-17 61.1 0.4 1.3e-16 60.1 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFQ92324.1 - 5.8e-06 26.7 0.3 2.9e-05 24.4 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KFQ92324.1 - 0.00014 21.9 0.8 0.0003 20.8 0.8 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KFQ92324.1 - 0.0048 16.8 0.1 0.007 16.3 0.1 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KFQ92324.1 - 0.008 16.7 0.8 0.011 16.2 0.8 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 KFQ92324.1 - 0.0094 16.3 1.2 0.013 15.9 0.0 1.8 1 1 1 2 2 2 1 Ubiquitin-like domain IBR PF01485.21 KFQ92324.1 - 0.039 14.2 4.2 0.064 13.5 4.2 1.4 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Ubiquitin_4 PF18036.1 KFQ92324.1 - 0.11 12.5 2.7 9.7 6.3 0.0 2.5 3 0 0 3 3 3 0 Ubiquitin-like domain GTP_EFTU PF00009.27 KFQ92325.1 - 4.6e-34 117.7 3.2 2.2e-32 112.2 3.2 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KFQ92325.1 - 7e-33 112.9 3.1 1e-32 112.3 1.5 2.2 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KFQ92325.1 - 9.1e-10 38.6 0.4 3.4e-09 36.8 0.1 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.21 KFQ92325.1 - 3.3e-05 23.4 0.4 0.00026 20.5 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.22 KFQ92325.1 - 0.001 18.7 0.0 0.0031 17.1 0.0 1.8 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFQ92325.1 - 0.0016 17.9 1.6 0.016 14.7 0.2 2.8 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KFQ92325.1 - 0.0019 17.7 0.1 0.006 16.1 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 KFQ92325.1 - 0.004 17.1 0.9 3 7.9 0.0 2.7 2 0 0 2 2 2 2 C-terminal region of MMR_HSR1 domain Roc PF08477.13 KFQ92325.1 - 0.0041 17.3 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D2 PF03144.25 KFQ92325.1 - 0.0084 16.5 0.1 1.2 9.5 0.0 3.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 Dynamin_N PF00350.23 KFQ92325.1 - 0.014 15.5 1.1 2.9 7.9 0.0 3.3 2 1 1 3 3 3 0 Dynamin family IF2_N PF04760.15 KFQ92325.1 - 0.014 15.2 1.2 0.12 12.2 0.1 2.5 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region GTP_EFTU_D4 PF14578.6 KFQ92325.1 - 0.015 15.2 0.7 0.14 12.0 0.1 2.5 2 0 0 2 2 2 0 Elongation factor Tu domain 4 AAA_26 PF13500.6 KFQ92325.1 - 0.041 13.7 0.3 0.13 12.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KFQ92325.1 - 5.1 7.5 0.0 5.1 7.5 0.0 3.2 3 1 0 3 3 2 0 AAA domain tRNA_edit PF04073.15 KFQ92326.1 - 2.7e-25 88.8 0.0 3.1e-25 88.6 0.0 1.0 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HTH_10 PF04967.12 KFQ92326.1 - 0.075 12.8 0.0 0.66 9.8 0.0 2.3 3 0 0 3 3 3 0 HTH DNA binding domain PRORP PF16953.5 KFQ92326.1 - 0.1 12.1 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein-only RNase P HOOK PF05622.12 KFQ92327.1 - 1.7e-35 122.4 67.7 1.7e-35 122.4 67.7 5.2 1 1 2 4 4 4 2 HOOK protein APG6_N PF17675.1 KFQ92327.1 - 0.0013 19.3 11.5 0.0013 19.3 11.5 15.1 2 1 10 13 13 13 4 Apg6 coiled-coil region DUF4472 PF14739.6 KFQ92327.1 - 0.0035 18.1 16.0 0.0035 18.1 16.0 15.3 4 3 11 16 16 16 3 Domain of unknown function (DUF4472) GAS PF13851.6 KFQ92327.1 - 0.0045 16.3 33.2 0.0045 16.3 33.2 12.5 1 1 10 12 12 12 5 Growth-arrest specific micro-tubule binding ARL2_Bind_BART PF11527.8 KFQ92328.1 - 1.3e-25 89.7 5.1 1.3e-25 89.7 5.1 1.5 2 0 0 2 2 2 1 The ARF-like 2 binding protein BART Ppx-GppA PF02541.16 KFQ92328.1 - 0.0083 15.6 1.2 0.011 15.2 1.2 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Reticulon PF02453.17 KFQ92328.1 - 0.034 14.1 0.1 0.055 13.4 0.1 1.3 1 0 0 1 1 1 0 Reticulon IL31 PF15209.6 KFQ92328.1 - 0.2 11.4 2.2 0.18 11.6 0.6 1.7 1 1 0 2 2 2 0 Interleukin 31 SMK-1 PF04802.15 KFQ92329.1 - 5e-60 202.6 2.7 5e-60 202.6 2.7 2.2 3 0 0 3 3 3 1 Component of IIS longevity pathway SMK-1 IGF2_C PF08365.11 KFQ92329.1 - 0.0044 17.0 0.2 0.013 15.4 0.2 1.8 1 0 0 1 1 1 1 Insulin-like growth factor II E-peptide RNase_PH PF01138.21 KFQ92330.1 - 8.3e-36 123.4 0.5 7.9e-22 78.2 0.0 2.9 2 1 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFQ92330.1 - 3.8e-15 55.7 0.7 5.4e-10 39.1 0.1 2.7 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 PNPase PF03726.14 KFQ92330.1 - 2.3e-10 40.8 0.3 6.6e-10 39.4 0.3 1.9 1 0 0 1 1 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain S1 PF00575.23 KFQ92330.1 - 1e-05 25.8 0.0 5e-05 23.6 0.0 2.2 3 0 0 3 3 3 1 S1 RNA binding domain KH_1 PF00013.29 KFQ92330.1 - 1.9e-05 24.4 0.0 0.00073 19.3 0.0 2.6 2 0 0 2 2 2 1 KH domain OAF PF14941.6 KFQ92330.1 - 0.019 14.4 0.2 0.041 13.3 0.2 1.5 1 0 0 1 1 1 0 Transcriptional regulator, Out at first EGF_CA PF07645.15 KFQ92331.1 - 1.4e-48 162.8 89.8 4.2e-14 52.5 7.2 8.0 8 0 0 8 8 8 6 Calcium-binding EGF domain cEGF PF12662.7 KFQ92331.1 - 2.2e-37 126.6 49.3 2.4e-10 40.1 0.6 7.3 7 0 0 7 7 7 6 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFQ92331.1 - 6e-10 39.2 87.0 6.4e-07 29.6 6.9 7.9 8 1 0 8 8 8 4 Coagulation Factor Xa inhibitory site EGF PF00008.27 KFQ92331.1 - 9.8e-08 32.2 88.3 0.00041 20.6 8.7 8.4 9 1 0 9 9 9 5 EGF-like domain EGF_3 PF12947.7 KFQ92331.1 - 0.00012 22.2 8.5 0.00012 22.2 8.5 8.5 8 2 0 8 8 8 4 EGF domain EGF_MSP1_1 PF12946.7 KFQ92331.1 - 0.00012 22.0 46.4 0.034 14.2 1.6 6.9 5 1 1 6 6 6 3 MSP1 EGF domain 1 hEGF PF12661.7 KFQ92331.1 - 0.00077 20.0 2.1 0.00077 20.0 2.1 10.4 12 0 0 12 12 12 5 Human growth factor-like EGF CCDC85 PF10226.9 KFQ92332.1 - 3.7e-95 317.1 12.7 3.7e-95 317.1 12.7 2.3 3 0 0 3 3 3 1 CCDC85 family AMH_N PF04709.12 KFQ92332.1 - 0.0054 15.7 0.8 0.0054 15.7 0.8 2.1 1 1 1 2 2 2 1 Anti-Mullerian hormone, N terminal region Cast PF10174.9 KFQ92332.1 - 0.016 13.5 8.1 0.01 14.1 6.2 1.5 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone TSC22 PF01166.18 KFQ92332.1 - 0.027 14.8 9.5 1.8 8.9 0.1 3.8 3 0 0 3 3 3 0 TSC-22/dip/bun family Ribosomal_L6e_N PF03868.15 KFQ92332.1 - 0.092 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L6, N-terminal domain bZIP_1 PF00170.21 KFQ92332.1 - 0.26 11.4 11.9 0.27 11.4 0.1 3.4 3 0 0 3 3 3 0 bZIP transcription factor Vir_act_alpha_C PF10400.9 KFQ92332.1 - 0.29 11.9 0.2 0.29 11.9 0.2 2.2 3 0 0 3 3 2 0 Virulence activator alpha C-term Shugoshin_N PF07558.11 KFQ92332.1 - 1.4 8.9 5.9 3.6 7.5 1.4 2.4 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region TMF_TATA_bd PF12325.8 KFQ92332.1 - 4.6 7.5 12.7 14 5.9 0.1 2.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding YabA PF06156.13 KFQ92332.1 - 5.3 7.7 9.1 11 6.7 0.4 3.5 2 1 1 3 3 3 0 Initiation control protein YabA Mod_r PF07200.13 KFQ92332.1 - 6.1 6.9 10.9 0.86 9.7 1.8 2.8 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Pkinase PF00069.25 KFQ92333.1 - 8.2e-17 61.4 0.0 1.1e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ92333.1 - 3.1e-09 36.5 0.1 1e-08 34.8 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFQ92333.1 - 0.0028 16.5 0.0 0.0032 16.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase WD-3 PF09765.9 KFQ92334.1 - 7.6e-107 356.9 0.6 8.7e-107 356.7 0.6 1.0 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.8 KFQ92334.1 - 1.3e-30 105.3 3.2 2.5e-30 104.5 3.2 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 KFQ92334.1 - 8.1e-06 26.1 2.9 2.1e-05 24.7 2.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-HC5HC2H PF13771.6 KFQ92334.1 - 0.052 13.8 0.1 0.1 12.9 0.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-ANAPC11 PF12861.7 KFQ92334.1 - 0.11 12.6 3.0 0.57 10.3 3.1 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KFQ92334.1 - 0.15 12.4 4.0 0.53 10.6 4.0 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain RINGv PF12906.7 KFQ92334.1 - 0.2 11.8 1.0 0.42 10.8 1.0 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C2H2 PF00096.26 KFQ92335.1 - 8e-27 92.2 55.3 5.3e-06 26.6 2.8 7.5 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ92335.1 - 1.9e-16 59.7 50.5 2.9e-07 30.6 1.3 8.6 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ92335.1 - 1.2e-15 56.8 51.8 0.0017 19.0 1.3 7.6 7 0 0 7 7 7 6 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFQ92335.1 - 5.3e-05 22.9 35.9 9.2e-05 22.1 3.9 4.8 5 0 0 5 5 4 2 C2H2-type zinc-finger domain DUF3268 PF11672.8 KFQ92335.1 - 0.00043 20.6 15.5 0.009 16.3 1.3 2.7 2 1 0 2 2 2 2 zinc-finger-containing domain BSP_II PF05432.11 KFQ92335.1 - 0.013 15.2 11.8 0.022 14.5 11.8 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RNA_pol_3_Rpc31 PF11705.8 KFQ92335.1 - 0.043 14.1 7.8 0.087 13.1 7.8 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 GAGA PF09237.11 KFQ92335.1 - 0.073 12.9 6.9 2.6 7.9 0.3 2.8 2 1 0 2 2 2 0 GAGA factor DUF2052 PF09747.9 KFQ92335.1 - 0.17 12.0 9.8 0.27 11.3 9.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Astro_capsid_p PF12226.8 KFQ92335.1 - 0.22 10.6 5.6 0.36 9.9 5.6 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein HTH_18 PF12833.7 KFQ92335.1 - 0.42 10.9 1.3 3.9 7.8 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain Actin_micro PF17003.5 KFQ92335.1 - 0.65 9.1 9.8 4.8 6.2 0.1 3.7 3 1 0 3 3 3 0 Putative actin-like family Ribosomal_60s PF00428.19 KFQ92335.1 - 0.69 10.5 11.7 1.4 9.5 11.7 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein NOA36 PF06524.12 KFQ92335.1 - 0.97 8.7 20.8 0.012 15.0 8.7 2.2 2 0 0 2 2 2 0 NOA36 protein DNA_pol_phi PF04931.13 KFQ92335.1 - 2.2 6.3 14.7 3 5.8 14.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 KFQ92335.1 - 3.2 8.2 14.4 6.9 7.1 14.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2256 PF10013.9 KFQ92335.1 - 3.8 7.7 14.2 14 5.9 0.4 4.9 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) FAM176 PF14851.6 KFQ92335.1 - 4.2 7.0 7.3 9.6 5.9 7.3 1.5 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 KFQ92335.1 - 5.1 5.3 6.6 7.3 4.8 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 KFQ92335.1 - 6.2 6.3 16.3 0.62 9.6 10.0 2.1 2 0 0 2 2 2 0 PPP4R2 RHD_DNA_bind PF00554.22 KFQ92336.1 - 1.8e-75 252.5 0.0 3.6e-75 251.6 0.0 1.5 1 0 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.5 KFQ92336.1 - 2.4e-37 127.1 0.0 4e-37 126.3 0.0 1.4 1 0 0 1 1 1 1 Rel homology dimerisation domain TPD PF14811.6 KFQ92337.1 - 0.081 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif TFIID_20kDa PF03847.13 KFQ92337.1 - 0.25 11.9 2.7 82 3.8 0.0 3.9 4 0 0 4 4 4 0 Transcription initiation factor TFIID subunit A DUF3342 PF11822.8 KFQ92338.1 - 6.2e-37 125.7 1.6 1.2e-36 124.7 1.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) CHORD PF04968.12 KFQ92338.1 - 0.45 11.3 7.8 0.15 12.8 3.0 2.8 2 1 0 2 2 2 0 CHORD Cadherin PF00028.17 KFQ92339.1 - 3.3e-26 91.5 0.2 3.4e-17 62.7 0.0 2.4 2 1 0 2 2 2 2 Cadherin domain RET_CLD1 PF17756.1 KFQ92339.1 - 0.01 16.2 0.0 4.8 7.5 0.0 2.2 2 0 0 2 2 2 2 RET Cadherin like domain 1 Cadherin PF00028.17 KFQ92341.1 - 6e-10 39.4 0.4 1.2e-09 38.4 0.1 1.7 2 0 0 2 2 2 1 Cadherin domain DUF3377 PF11857.8 KFQ92341.1 - 0.0089 15.9 2.0 0.013 15.4 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3377) COX6C PF02937.15 KFQ92341.1 - 0.023 14.8 0.4 0.055 13.6 0.4 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc Syndecan PF01034.20 KFQ92341.1 - 0.1 12.6 0.2 0.21 11.6 0.2 1.5 1 0 0 1 1 1 0 Syndecan domain Stevor PF17410.2 KFQ92341.1 - 0.11 12.0 3.3 0.28 10.7 1.4 1.9 1 1 1 2 2 2 0 Subtelomeric Variable Open Reading frame Aha1_N PF09229.11 KFQ92342.1 - 5.2e-38 130.4 2.2 1e-37 129.4 1.6 1.7 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KFQ92342.1 - 3.4e-17 62.8 0.1 1.4e-16 60.9 0.0 1.9 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein CRM1_C PF08767.11 KFQ92343.1 - 2e-135 451.1 1.6 2e-135 451.1 1.6 2.9 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 KFQ92343.1 - 3.5e-37 127.7 3.7 3.5e-37 127.7 3.7 5.2 6 1 0 6 6 6 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KFQ92343.1 - 7.7e-36 121.6 2.0 2.8e-35 119.8 2.0 2.1 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KFQ92343.1 - 2e-30 104.6 0.7 2e-30 104.6 0.7 2.6 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KFQ92343.1 - 2.3e-18 65.4 3.2 4.6e-18 64.4 3.2 1.6 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KFQ92343.1 - 1.8e-12 46.9 0.7 9.2e-12 44.7 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Hydrolase_3 PF08282.12 KFQ92343.1 - 0.065 13.0 2.5 0.12 12.1 0.0 2.6 3 1 1 4 4 4 0 haloacid dehalogenase-like hydrolase Vac14_Fab1_bd PF12755.7 KFQ92343.1 - 0.61 10.7 2.7 4.3 8.0 0.1 3.7 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region UPF0564 PF10595.9 KFQ92344.1 - 1.2e-58 198.9 48.8 1.2e-58 198.9 48.8 1.6 2 0 0 2 2 2 1 Uncharacterised protein family UPF0564 Metal_resist PF13801.6 KFQ92344.1 - 4.3 7.6 9.0 0.92 9.7 2.7 2.5 2 0 0 2 2 2 0 Heavy-metal resistance Cpn60_TCP1 PF00118.24 KFQ92345.1 - 4.5e-157 523.6 15.6 5.1e-157 523.4 15.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.12 KFQ92345.1 - 0.069 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Phage Tail Protein X FERM_M PF00373.18 KFQ92346.1 - 6.7e-42 142.6 0.0 1.6e-41 141.4 0.0 1.7 1 1 0 1 1 1 1 FERM central domain Kindlin_2_N PF18124.1 KFQ92346.1 - 2.4e-34 117.4 5.0 6.3e-34 116.0 5.0 1.8 1 0 0 1 1 1 1 Kindlin-2 N-terminal domain PH PF00169.29 KFQ92346.1 - 4.7e-11 43.1 0.0 4.2e-10 40.1 0.0 2.4 2 0 0 2 2 2 1 PH domain FERM_N PF09379.10 KFQ92346.1 - 0.011 15.7 0.0 0.036 14.0 0.0 2.0 1 1 0 1 1 1 0 FERM N-terminal domain Rad10 PF03834.14 KFQ92346.1 - 0.17 11.9 2.1 9.6 6.3 0.1 3.0 3 0 0 3 3 3 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) TGFb_propeptide PF00688.18 KFQ92347.1 - 1.2e-36 126.7 0.4 2e-36 126.0 0.4 1.3 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 KFQ92347.1 - 1e-34 119.6 0.6 1.9e-34 118.7 0.6 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain FMN_dh PF01070.18 KFQ92348.1 - 2.8e-129 431.1 4.1 2.8e-128 427.8 4.1 1.9 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KFQ92348.1 - 3.5e-06 26.3 0.9 3.5e-06 26.3 0.9 1.8 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFQ92348.1 - 5.1e-05 22.6 0.1 9.1e-05 21.7 0.1 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 KFQ92348.1 - 0.00011 21.6 0.6 0.29 10.4 0.1 2.5 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KFQ92348.1 - 0.00038 20.0 0.4 0.0051 16.3 0.1 2.4 1 1 1 2 2 2 1 Histidine biosynthesis protein NMO PF03060.15 KFQ92348.1 - 0.0021 17.5 1.8 0.0057 16.1 1.7 1.7 1 1 0 1 1 1 1 Nitronate monooxygenase TMP-TENI PF02581.17 KFQ92348.1 - 0.0069 15.7 0.7 0.051 12.9 0.0 2.5 3 0 0 3 3 3 1 Thiamine monophosphate synthase Dus PF01207.17 KFQ92348.1 - 0.012 14.7 0.1 4.1 6.4 0.0 2.4 2 1 1 3 3 3 0 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 KFQ92348.1 - 0.013 14.8 0.4 0.035 13.3 0.0 1.9 3 0 0 3 3 3 0 Dihydroorotate dehydrogenase MFS_MOT1 PF16983.5 KFQ92348.1 - 0.032 14.7 0.2 0.063 13.7 0.2 1.5 1 0 0 1 1 1 0 Molybdate transporter of MFS superfamily G3P_antiterm PF04309.12 KFQ92348.1 - 0.054 12.9 0.2 7.3 6.0 0.0 2.5 2 1 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator CdhD PF03599.16 KFQ92348.1 - 0.057 12.1 0.0 0.088 11.5 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Thioredoxin PF00085.20 KFQ92349.1 - 1.6e-13 50.5 0.0 2e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin zf-IS66 PF13005.7 KFQ92349.1 - 0.16 12.4 0.1 0.26 11.7 0.1 1.3 1 0 0 1 1 1 0 zinc-finger binding domain of transposase IS66 PI-PLC-X PF00388.19 KFQ92350.1 - 1.1e-58 197.0 0.3 4.4e-58 195.0 0.0 2.3 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PLC-beta_C PF08703.10 KFQ92350.1 - 4.7e-47 160.2 46.6 4.7e-47 160.2 46.6 3.0 3 0 0 3 3 3 1 PLC-beta C terminal PI-PLC-Y PF00387.19 KFQ92350.1 - 5.9e-40 136.2 1.5 5.9e-40 136.2 1.5 4.0 2 1 2 4 4 4 1 Phosphatidylinositol-specific phospholipase C, Y domain PH_14 PF17787.1 KFQ92350.1 - 4.6e-19 68.6 0.0 1.3e-18 67.1 0.0 1.8 1 0 0 1 1 1 1 PH domain EF-hand_like PF09279.11 KFQ92350.1 - 5.6e-11 42.8 0.0 5.6e-11 42.8 0.0 3.2 2 1 2 4 4 4 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 KFQ92350.1 - 2.2e-07 31.1 0.2 8.1e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 C2 domain DUF1154 PF06631.11 KFQ92350.1 - 1e-06 28.7 10.8 1e-06 28.7 10.8 3.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1154) DUF760 PF05542.11 KFQ92350.1 - 0.057 13.8 0.4 15 6.0 0.3 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF760) DUF4510 PF14971.6 KFQ92350.1 - 0.88 9.9 12.0 19 5.6 9.4 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4510) PI-PLC-X PF00388.19 KFQ92351.1 - 7.9e-63 210.4 1.7 1.5e-62 209.5 0.0 2.3 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PH_14 PF17787.1 KFQ92351.1 - 6.7e-44 148.9 0.0 6.7e-44 148.9 0.0 2.5 2 1 0 2 2 2 1 PH domain PI-PLC-Y PF00387.19 KFQ92351.1 - 3.3e-42 143.5 0.4 3.3e-42 143.5 0.4 4.1 3 1 1 4 4 4 1 Phosphatidylinositol-specific phospholipase C, Y domain DUF1154 PF06631.11 KFQ92351.1 - 2.8e-17 62.4 13.1 2.8e-17 62.4 13.1 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1154) EF-hand_like PF09279.11 KFQ92351.1 - 1.3e-13 51.2 1.2 5.7e-13 49.2 0.0 2.7 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 KFQ92351.1 - 1.8e-08 34.6 0.0 4.8e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.6 KFQ92351.1 - 0.092 13.2 0.6 0.41 11.1 0.6 2.2 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 KFQ92351.1 - 0.15 12.0 0.6 0.56 10.3 0.6 2.0 1 0 0 1 1 1 0 EF-hand domain Pkinase PF00069.25 KFQ92352.1 - 1.3e-68 231.2 0.0 1.8e-68 230.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ92352.1 - 4.9e-45 153.8 0.0 6.9e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KFQ92352.1 - 1.5e-15 57.3 0.1 4.2e-15 55.8 0.1 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KFQ92352.1 - 4.2e-08 32.8 0.0 1.1e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFQ92352.1 - 8.2e-05 21.6 0.0 0.00015 20.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFQ92352.1 - 0.11 12.5 0.2 3.3 7.5 0.0 2.9 1 1 2 3 3 3 0 Phosphotransferase enzyme family adh_short PF00106.25 KFQ92353.1 - 1.7e-21 76.6 0.0 2.6e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFQ92353.1 - 4.7e-14 52.5 0.0 5.7e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KFQ92353.1 - 3.4e-06 26.6 0.0 4e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) HMG_box PF00505.19 KFQ92353.1 - 0.0012 19.2 0.5 0.0044 17.4 0.1 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box TDH PF03347.13 KFQ92353.1 - 0.03 13.9 0.1 0.047 13.3 0.1 1.2 1 0 0 1 1 1 0 Vibrio thermostable direct hemolysin Ank_2 PF12796.7 KFQ92354.1 - 2.1e-51 172.4 3.8 2.5e-10 40.8 0.0 5.7 4 1 2 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ92354.1 - 1.6e-42 143.3 10.1 1.5e-14 54.1 0.1 8.8 4 2 5 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ92354.1 - 4.1e-42 137.3 7.3 8.6e-07 28.8 0.0 10.5 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 KFQ92354.1 - 7.6e-41 137.6 16.2 7.1e-08 32.6 0.0 8.9 6 3 4 10 10 10 7 Ankyrin repeats (many copies) Ank PF00023.30 KFQ92354.1 - 6.6e-40 133.9 10.6 8.1e-07 29.2 0.0 9.5 8 1 0 8 8 8 8 Ankyrin repeat SNAP-25 PF00835.19 KFQ92355.1 - 1.3e-21 76.6 0.2 2.7e-21 75.6 0.2 1.6 1 0 0 1 1 1 1 SNAP-25 family DUF5089 PF17002.5 KFQ92355.1 - 6.4e-05 22.9 0.1 8.6e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5089) V-SNARE_C PF12352.8 KFQ92355.1 - 0.069 13.4 3.1 0.37 11.1 0.1 2.7 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus DUF349 PF03993.12 KFQ92355.1 - 0.12 12.6 1.1 0.43 10.9 0.1 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Rx_N PF18052.1 KFQ92355.1 - 0.16 12.3 1.8 0.49 10.7 0.1 2.0 2 0 0 2 2 2 0 Rx N-terminal domain FlaC_arch PF05377.11 KFQ92355.1 - 8.4 6.9 7.5 19 5.8 1.1 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Cpn60_TCP1 PF00118.24 KFQ92356.1 - 2.6e-96 323.2 0.0 2.9e-96 323.0 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family UPF0492 PF15744.5 KFQ92357.1 - 1e-150 502.1 11.6 1.3e-150 501.8 11.6 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0492 EGF PF00008.27 KFQ92358.1 - 4.6e-80 263.4 286.0 2e-09 37.6 7.7 19.4 19 1 0 19 19 19 14 EGF-like domain hEGF PF12661.7 KFQ92358.1 - 8.9e-54 178.4 256.7 4.8e-07 30.2 7.3 20.9 22 0 0 22 22 22 14 Human growth factor-like EGF MNNL PF07657.13 KFQ92358.1 - 5.1e-28 96.9 3.4 5.1e-28 96.9 3.4 6.7 7 1 0 7 7 7 1 N terminus of Notch ligand EGF_2 PF07974.13 KFQ92358.1 - 8.7e-26 90.0 332.8 0.00029 21.1 11.1 19.7 20 0 0 20 20 20 13 EGF-like domain DSL PF01414.19 KFQ92358.1 - 4.4e-24 84.5 7.7 4.4e-24 84.5 7.7 15.6 12 2 4 16 16 16 2 Delta serrate ligand EGF_CA PF07645.15 KFQ92358.1 - 3e-08 33.7 284.8 5.8e-05 23.2 8.8 19.3 10 4 11 21 21 21 11 Calcium-binding EGF domain DUF2920 PF11144.8 KFQ92358.1 - 0.0042 16.3 0.6 0.0068 15.6 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) cEGF PF12662.7 KFQ92358.1 - 0.011 15.7 3.3 0.011 15.7 3.3 17.7 16 3 0 16 16 16 0 Complement Clr-like EGF-like MAP17 PF15807.5 KFQ92358.1 - 0.14 12.4 0.8 0.27 11.5 0.8 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 CLN3 PF02487.17 KFQ92358.1 - 0.33 9.9 0.2 0.48 9.4 0.2 1.1 1 0 0 1 1 1 0 CLN3 protein PHR PF08005.12 KFQ92360.1 - 1.3e-43 149.3 2.1 1.4e-43 149.2 0.9 1.7 2 0 0 2 2 2 1 PHR domain BTB PF00651.31 KFQ92360.1 - 5.1e-24 84.6 0.0 3.2e-23 82.1 0.0 2.2 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFQ92360.1 - 9.3e-08 32.1 3.5 1.1e-07 31.8 1.4 2.2 2 1 0 2 2 2 1 BTB And C-terminal Kelch Aminotran_1_2 PF00155.21 KFQ92361.1 - 1.4e-55 188.9 0.0 1.8e-55 188.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KFQ92361.1 - 0.00028 20.3 0.0 0.00045 19.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KFQ92361.1 - 0.0044 16.0 0.0 0.0063 15.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Raf1_HTH PF18579.1 KFQ92361.1 - 0.084 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain Cyd_oper_YbgE PF09600.10 KFQ92361.1 - 0.094 13.1 0.1 27 5.2 0.0 2.5 2 0 0 2 2 2 0 Cyd operon protein YbgE (Cyd_oper_YbgE) AMOP PF03782.17 KFQ92362.1 - 1.2e-24 87.0 5.1 1.2e-24 87.0 5.1 2.1 2 0 0 2 2 2 1 AMOP domain TSP_1 PF00090.19 KFQ92362.1 - 3.8e-07 30.2 12.4 3.8e-07 30.2 12.4 2.6 2 0 0 2 2 2 1 Thrombospondin type 1 domain Asparaginase_2 PF01112.18 KFQ92363.1 - 1.3e-51 175.5 0.2 2.5e-51 174.5 0.2 1.5 1 0 0 1 1 1 1 Asparaginase Methyltransf_11 PF08241.12 KFQ92364.1 - 1.7e-22 79.8 0.0 2.8e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFQ92364.1 - 2.4e-17 63.4 0.0 3.9e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFQ92364.1 - 7.9e-16 58.3 0.0 1.1e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFQ92364.1 - 5e-13 49.1 0.0 8.7e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFQ92364.1 - 3.8e-11 43.6 0.0 6.1e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFQ92364.1 - 1.9e-10 40.5 0.0 3.1e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 KFQ92364.1 - 1e-06 27.6 0.0 1.4e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.12 KFQ92364.1 - 0.00035 20.2 0.0 0.00049 19.7 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 KFQ92364.1 - 0.001 19.0 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 KFQ92364.1 - 0.0012 18.4 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 KFQ92364.1 - 0.02 14.8 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 KFQ92364.1 - 0.058 13.0 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_7 PF03492.15 KFQ92364.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase Pox_MCEL PF03291.16 KFQ92364.1 - 0.12 11.4 0.0 3 6.9 0.0 2.0 1 1 1 2 2 2 0 mRNA capping enzyme Methyltransf_PK PF05891.12 KFQ92364.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase LRR_8 PF13855.6 KFQ92365.1 - 2.1e-30 104.2 41.2 8.9e-14 51.0 5.2 5.8 3 1 3 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 KFQ92365.1 - 7.7e-15 54.8 42.3 0.0055 17.1 0.8 6.8 3 1 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFQ92365.1 - 3.9e-09 36.2 9.0 0.00041 19.9 1.7 3.5 2 1 1 3 3 3 3 Leucine-rich repeat LRR_5 PF13306.6 KFQ92365.1 - 1e-07 32.0 0.0 0.00014 21.8 0.0 3.6 1 1 2 4 4 4 2 BspA type Leucine rich repeat region (6 copies) LRRNT PF01462.18 KFQ92365.1 - 1.9e-05 24.2 3.9 6.1e-05 22.6 2.3 2.6 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRRCT PF01463.24 KFQ92365.1 - 0.0024 18.3 0.0 0.007 16.8 0.0 1.9 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain fn3 PF00041.21 KFQ92365.1 - 0.01 16.2 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III domain TPKR_C2 PF16920.5 KFQ92365.1 - 0.075 13.2 0.8 0.27 11.4 0.2 2.3 2 0 0 2 2 2 0 Tyrosine-protein kinase receptor C2 Ig-like domain Kinesin PF00225.23 KFQ92366.1 - 1.4e-109 366.0 0.8 1.4e-109 366.0 0.8 3.8 3 1 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 KFQ92366.1 - 6.1e-23 81.4 0.1 6.1e-23 81.4 0.1 3.1 3 0 0 3 3 3 1 Microtubule binding PX PF00787.24 KFQ92366.1 - 3.4e-16 59.2 0.6 3.4e-16 59.2 0.6 3.4 4 0 0 4 4 4 1 PX domain Kinesin_assoc PF16183.5 KFQ92366.1 - 2.8e-09 37.4 3.8 1.1e-05 25.6 0.3 6.2 2 2 4 6 6 6 2 Kinesin-associated Yop-YscD_cpl PF16697.5 KFQ92366.1 - 1.1e-05 25.7 1.0 9.6e-05 22.6 0.0 3.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain AAA_16 PF13191.6 KFQ92366.1 - 2.2 8.6 0.0 2.2 8.6 0.0 4.6 3 2 0 3 3 3 0 AAA ATPase domain RRM_1 PF00076.22 KFQ92367.1 - 3.6e-27 94.0 0.7 7.6e-15 54.5 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFQ92367.1 - 1.2e-08 34.7 0.0 0.0004 20.2 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KFQ92367.1 - 9.2e-08 31.7 0.1 0.0059 16.2 0.1 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_dom-like PF14714.6 KFQ92367.1 - 0.045 14.1 0.1 0.38 11.1 0.1 2.4 2 0 0 2 2 2 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal DUF1027 PF06265.11 KFQ92367.1 - 0.19 11.8 0.6 0.77 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1027) SH3_2 PF07653.17 KFQ92368.1 - 2.4e-19 68.7 0.0 3.4e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFQ92368.1 - 0.0031 17.3 0.0 0.0051 16.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_S8 PF00082.22 KFQ92369.1 - 1.2e-42 146.3 3.0 1.5e-42 145.9 3.0 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KFQ92369.1 - 3.4e-25 87.9 0.1 6.8e-25 86.9 0.1 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KFQ92369.1 - 1.6e-08 35.2 1.7 3e-08 34.3 1.7 1.5 1 0 0 1 1 1 1 Peptidase S8 pro-domain Peptidase_S8_N PF16361.5 KFQ92369.1 - 0.023 15.2 0.0 0.047 14.2 0.0 1.5 1 0 0 1 1 1 0 N-terminal of Subtilase family Filament PF00038.21 KFQ92370.1 - 4.5e-24 85.6 48.0 1.6e-22 80.5 19.8 2.8 3 0 0 3 3 3 2 Intermediate filament protein TPR_MLP1_2 PF07926.12 KFQ92370.1 - 0.0033 17.5 10.3 0.0033 17.5 10.3 4.4 3 1 1 4 4 4 1 TPR/MLP1/MLP2-like protein ApoO PF09769.9 KFQ92370.1 - 0.1 12.6 6.6 1.6 8.7 0.8 4.2 3 1 1 4 4 4 0 Apolipoprotein O DUF5065 PF16723.5 KFQ92370.1 - 0.14 12.2 1.2 0.44 10.6 1.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5065) LemA PF04011.12 KFQ92370.1 - 0.58 10.0 20.4 0.045 13.6 1.9 3.3 2 1 1 3 3 3 0 LemA family Baculo_PEP_C PF04513.12 KFQ92370.1 - 0.73 9.9 12.7 0.16 12.0 1.2 3.3 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus PSI_PsaF PF02507.15 KFQ92370.1 - 1.4 8.7 7.8 4.3 7.2 0.8 3.7 3 1 0 3 3 3 0 Photosystem I reaction centre subunit III KASH_CCD PF14662.6 KFQ92370.1 - 8.1 6.2 39.6 1 9.2 14.6 3.9 2 1 2 4 4 4 0 Coiled-coil region of CCDC155 or KASH Lectin_N PF03954.14 KFQ92370.1 - 8.3 6.2 7.6 0.71 9.6 1.1 2.5 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain 7tm_1 PF00001.21 KFQ92371.1 - 1.2e-46 159.2 24.0 1.5e-46 158.9 24.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ92371.1 - 1.3e-05 24.7 27.5 1.8e-05 24.3 27.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx V-set PF07686.17 KFQ92372.1 - 1.3e-15 57.5 1.0 1.7e-05 24.9 0.1 4.2 4 0 0 4 4 4 3 Immunoglobulin V-set domain Tcell_CD4_C PF12104.8 KFQ92372.1 - 1.8e-11 43.7 11.9 4e-11 42.6 11.9 1.6 1 0 0 1 1 1 1 T cell CD4 receptor C terminal region Ig_2 PF13895.6 KFQ92372.1 - 6.7e-11 42.4 0.1 0.16 12.3 0.0 4.3 4 0 0 4 4 4 3 Immunoglobulin domain Ig_3 PF13927.6 KFQ92372.1 - 1.9e-10 41.2 0.4 0.17 12.5 0.1 4.4 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 KFQ92372.1 - 3.1e-10 40.1 0.4 0.17 12.1 0.0 4.5 4 0 0 4 4 4 3 Immunoglobulin domain CD4-extracel PF09191.10 KFQ92372.1 - 3.1e-07 30.8 0.2 6.9e-07 29.7 0.2 1.5 1 0 0 1 1 1 1 CD4, extracellular I-set PF07679.16 KFQ92372.1 - 4.9e-07 29.7 0.2 0.25 11.5 0.0 4.5 4 2 0 4 4 4 2 Immunoglobulin I-set domain C2-set PF05790.15 KFQ92372.1 - 4.8e-06 26.7 0.2 0.37 11.0 0.0 4.5 4 0 0 4 4 4 2 Immunoglobulin C2-set domain Izumo-Ig PF16706.5 KFQ92372.1 - 1.6e-05 24.8 0.0 3.7 7.7 0.0 4.2 4 0 0 4 4 4 2 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFQ92372.1 - 2e-05 24.0 0.0 1.8 8.2 0.0 3.7 4 0 0 4 4 4 2 Immunoglobulin domain V-set_CD47 PF08204.11 KFQ92372.1 - 0.0029 17.6 0.6 0.24 11.4 0.3 3.7 3 1 1 4 4 4 1 CD47 immunoglobulin-like domain Ig_4 PF16680.5 KFQ92372.1 - 0.0031 17.7 0.5 13 6.1 0.0 4.3 4 1 0 5 5 5 0 T-cell surface glycoprotein CD3 delta chain Filamin PF00630.19 KFQ92372.1 - 0.11 13.3 0.2 1.5 9.6 0.3 2.7 2 1 0 2 2 2 0 Filamin/ABP280 repeat PMP1_2 PF08114.11 KFQ92372.1 - 0.21 11.4 1.2 0.38 10.5 1.2 1.3 1 0 0 1 1 1 0 ATPase proteolipid family 7tm_1 PF00001.21 KFQ92373.1 - 0.0038 16.6 2.4 0.0067 15.8 2.4 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) WD40 PF00400.32 KFQ92374.1 - 1.1e-44 149.5 21.2 3.8e-08 33.9 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ92374.1 - 5.3e-17 61.9 0.0 0.00041 20.6 0.1 5.7 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFQ92374.1 - 1.7e-08 34.6 0.0 0.04 13.8 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KFQ92374.1 - 1.1e-05 24.9 0.1 0.0017 17.7 0.0 3.2 1 1 2 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 KFQ92374.1 - 0.0018 17.3 1.8 15 4.4 0.0 4.3 2 1 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KFQ92374.1 - 0.0045 15.6 0.0 0.022 13.3 0.0 1.9 2 0 0 2 2 2 1 Cytochrome D1 heme domain TIM PF00121.18 KFQ92375.1 - 7.4e-80 267.8 0.1 8.2e-80 267.7 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Laminin_G_2 PF02210.24 KFQ92376.1 - 2.4e-134 441.8 9.1 1.3e-28 100.1 0.0 5.2 5 0 0 5 5 5 5 Laminin G domain Laminin_G_1 PF00054.23 KFQ92376.1 - 1.3e-86 287.5 4.5 1e-24 87.2 0.0 6.5 5 1 0 5 5 5 5 Laminin G domain Laminin_G_3 PF13385.6 KFQ92376.1 - 1.1e-16 61.3 2.9 0.04 14.1 0.0 5.4 5 0 0 5 5 5 5 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 KFQ92376.1 - 8.3e-09 35.6 17.5 1.2e-05 25.5 6.7 2.7 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 KFQ92376.1 - 9.2e-05 22.9 14.7 0.02 15.5 5.3 3.0 2 0 0 2 2 2 2 Human growth factor-like EGF DUF1080 PF06439.11 KFQ92376.1 - 0.0041 17.2 0.0 7.2 6.7 0.0 3.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF1080) Plasmod_Pvs28 PF06247.11 KFQ92376.1 - 8.5 6.8 10.9 0.15 12.4 1.7 2.5 2 0 0 2 2 2 0 Pvs28 EGF domain DNA_pol_B PF00136.21 KFQ92378.1 - 2.4e-131 438.6 1.4 3.5e-131 438.1 1.4 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KFQ92378.1 - 1.4e-59 202.0 0.0 3.8e-59 200.5 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.10 KFQ92378.1 - 7.5e-54 182.3 6.9 1.4e-53 181.4 6.9 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_alpha_N PF12254.8 KFQ92378.1 - 3e-16 59.3 10.9 3e-16 59.3 10.9 2.7 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal DUF1744 PF08490.12 KFQ92378.1 - 0.00017 20.3 0.5 0.00073 18.2 0.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1744) DNA_pol_B_2 PF03175.13 KFQ92378.1 - 0.0023 16.9 0.0 0.0056 15.6 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral CTP_transf_like PF01467.26 KFQ92379.1 - 5.4e-32 110.9 0.4 1e-31 110.0 0.0 1.6 2 0 0 2 2 2 1 Cytidylyltransferase-like Lipoprotein_6 PF01441.19 KFQ92379.1 - 0.074 13.1 1.9 0.12 12.3 1.9 1.2 1 0 0 1 1 1 0 Lipoprotein YtxH PF12732.7 KFQ92379.1 - 0.14 12.7 1.9 0.27 11.8 1.9 1.5 1 0 0 1 1 1 0 YtxH-like protein BCDHK_Adom3 PF10436.9 KFQ92380.1 - 3.2e-46 157.1 0.0 4.8e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KFQ92380.1 - 4.3e-13 49.8 0.0 6.7e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFQ92380.1 - 0.0079 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Solute_trans_a PF03619.16 KFQ92381.1 - 1.2e-40 139.7 19.6 1.5e-40 139.4 19.6 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Wzy_C_2 PF11846.8 KFQ92381.1 - 3.2 7.6 5.2 0.38 10.6 0.4 1.9 2 1 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal Zfx_Zfy_act PF04704.13 KFQ92382.1 - 6.3e-152 505.4 18.9 6.3e-152 505.4 18.9 1.6 2 0 0 2 2 2 1 Zfx / Zfy transcription activation region zf-C2H2 PF00096.26 KFQ92382.1 - 9.3e-43 142.4 116.6 1e-05 25.7 2.1 13.4 13 0 0 13 13 13 12 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ92382.1 - 1.6e-37 126.3 121.8 2.7e-08 33.9 1.2 13.7 14 0 0 14 14 13 12 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ92382.1 - 3.7e-32 108.2 110.5 0.00016 22.2 0.9 13.4 13 0 0 13 13 13 13 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFQ92382.1 - 1.1e-25 89.0 105.6 4.4e-07 29.5 5.8 12.6 12 1 0 12 12 12 8 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFQ92382.1 - 5.4e-11 42.5 76.3 0.028 14.7 0.1 12.3 13 0 0 13 13 12 7 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 KFQ92382.1 - 4.2e-08 33.8 49.4 0.028 15.2 2.4 7.3 4 2 3 7 7 7 5 zinc-ribbon family zf-C2H2_3rep PF18868.1 KFQ92382.1 - 0.00084 20.0 45.1 0.17 12.6 5.7 7.9 2 1 4 7 7 7 3 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 KFQ92382.1 - 0.0036 17.2 11.1 0.0084 16.1 1.0 10.0 11 0 0 11 11 10 5 C2H2-type zinc finger zf-BED PF02892.15 KFQ92382.1 - 0.0057 16.6 2.7 0.0057 16.6 2.7 10.3 3 3 8 11 11 11 4 BED zinc finger zf-C2H2_11 PF16622.5 KFQ92382.1 - 0.021 14.6 0.2 0.021 14.6 0.2 10.4 13 0 0 13 13 13 0 zinc-finger C2H2-type zf-met PF12874.7 KFQ92382.1 - 0.15 12.5 0.0 0.15 12.5 0.0 11.4 12 1 1 13 13 12 0 Zinc-finger of C2H2 type zf-RING_7 PF02591.15 KFQ92382.1 - 2.7 8.3 11.8 27 5.1 0.1 5.7 5 0 0 5 5 5 0 C4-type zinc ribbon domain eIF2_C PF09173.11 KFQ92383.1 - 4.9e-31 106.8 1.4 8.1e-31 106.1 0.2 2.0 2 0 0 2 2 2 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KFQ92383.1 - 4.2e-23 81.9 1.1 3.8e-22 78.8 1.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KFQ92383.1 - 6.1e-13 49.0 0.3 1.6e-12 47.6 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KFQ92383.1 - 0.0028 17.6 0.4 0.023 14.6 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KFQ92383.1 - 0.0029 17.7 0.0 0.0061 16.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KFQ92383.1 - 0.013 15.5 0.1 0.026 14.5 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain G-alpha PF00503.20 KFQ92383.1 - 0.1 11.7 0.1 0.78 8.8 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit Dynamin_N PF00350.23 KFQ92383.1 - 0.13 12.4 0.3 0.6 10.1 0.1 2.0 1 1 0 2 2 2 0 Dynamin family Kelch_1 PF01344.25 KFQ92384.1 - 1.1e-40 137.0 7.6 3e-11 42.7 0.1 5.4 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 KFQ92384.1 - 2.3e-34 116.5 4.8 1.5e-08 34.6 0.2 6.2 3 2 2 5 5 5 5 Kelch motif BTB PF00651.31 KFQ92384.1 - 1.5e-23 83.2 1.9 1.5e-23 83.2 1.9 2.2 3 0 0 3 3 3 1 BTB/POZ domain Kelch_4 PF13418.6 KFQ92384.1 - 1.6e-20 72.8 1.3 0.0049 16.9 0.0 5.9 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KFQ92384.1 - 7.5e-18 64.4 0.8 0.00014 22.1 0.1 5.7 5 2 0 5 5 5 4 Galactose oxidase, central domain BACK PF07707.15 KFQ92384.1 - 5.8e-16 58.5 0.9 8.1e-16 58.0 0.1 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 KFQ92384.1 - 2.4e-14 52.7 11.4 0.0012 18.8 0.0 6.1 6 1 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 KFQ92384.1 - 1.8e-08 34.2 8.6 0.062 13.3 0.0 5.3 5 0 0 5 5 5 4 Kelch motif ApoO PF09769.9 KFQ92385.1 - 5e-37 126.8 0.0 5.6e-37 126.6 0.0 1.0 1 0 0 1 1 1 1 Apolipoprotein O Acetyltransf_1 PF00583.25 KFQ92386.1 - 1.3e-16 60.9 0.1 1.5e-16 60.7 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFQ92386.1 - 7.2e-08 32.8 0.0 1.1e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFQ92386.1 - 4.9e-05 23.3 0.0 7e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFQ92386.1 - 0.00067 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KFQ92386.1 - 0.017 15.8 0.0 0.02 15.6 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain 4HBT PF03061.22 KFQ92387.1 - 2.5e-09 37.4 0.0 0.0015 18.9 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily AhpC-TSA PF00578.21 KFQ92388.1 - 3.3e-34 117.5 0.0 4.2e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFQ92388.1 - 1e-11 44.7 0.0 1.3e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KFQ92388.1 - 8.2e-11 41.6 0.1 2.2e-10 40.2 0.1 1.8 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Patched PF02460.18 KFQ92389.1 - 2.6e-95 320.2 23.0 4.5e-95 319.4 23.0 1.3 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 KFQ92389.1 - 2e-19 69.9 1.6 2e-19 69.9 1.6 2.5 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Peptidase_M13_N PF05649.13 KFQ92391.1 - 2e-109 366.8 2.2 2.5e-109 366.5 2.2 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFQ92391.1 - 6.2e-65 218.6 1.1 8.9e-65 218.1 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M13 DED PF01335.21 KFQ92391.1 - 0.11 12.8 0.2 0.37 11.1 0.2 1.9 1 0 0 1 1 1 0 Death effector domain SpmSyn_N PF17950.1 KFQ92392.1 - 8.4e-51 170.1 0.1 1.5e-50 169.4 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase N -terminal Spermine_synth PF01564.17 KFQ92392.1 - 9.2e-45 152.4 0.1 1.4e-44 151.7 0.1 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KFQ92392.1 - 3e-18 65.5 0.0 6e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Citrate_bind PF16114.5 KFQ92392.1 - 0.034 13.6 0.0 0.31 10.5 0.0 2.1 2 0 0 2 2 2 0 ATP citrate lyase citrate-binding Chisel PF15355.6 KFQ92393.1 - 1.3e-40 137.5 3.2 1.4e-40 137.4 3.2 1.0 1 0 0 1 1 1 1 Stretch-responsive small skeletal muscle X protein, Chisel Kelch_1 PF01344.25 KFQ92394.1 - 9.2e-38 127.6 0.3 6.1e-10 38.5 0.0 6.0 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KFQ92394.1 - 2.4e-32 110.1 2.1 1.5e-08 34.6 0.0 6.3 2 2 4 6 6 6 4 Kelch motif Kelch_4 PF13418.6 KFQ92394.1 - 4.5e-27 93.8 1.2 2.2e-08 33.9 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain BTB PF00651.31 KFQ92394.1 - 3.1e-26 91.8 1.0 4.8e-26 91.2 0.5 1.6 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.6 KFQ92394.1 - 7.6e-19 67.5 0.2 0.0065 16.7 0.0 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KFQ92394.1 - 7.9e-15 54.2 4.6 2.2e-05 24.3 0.1 5.5 5 2 0 5 5 5 4 Kelch motif BACK PF07707.15 KFQ92394.1 - 7.9e-11 42.0 0.1 1.6e-10 41.0 0.1 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 KFQ92394.1 - 3.5e-10 39.6 1.9 0.003 17.5 0.0 5.7 6 0 0 6 6 6 2 Kelch motif DUF1170 PF06663.13 KFQ92395.1 - 5.1e-62 209.3 9.2 5.1e-62 209.3 9.2 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF1170) CRIC_ras_sig PF10534.9 KFQ92395.1 - 2.3e-39 133.5 0.5 7.9e-39 131.7 0.1 2.2 2 0 0 2 2 2 1 Connector enhancer of kinase suppressor of ras SAM_1 PF00536.30 KFQ92395.1 - 1.8e-15 57.1 1.8 7.3e-15 55.2 0.3 2.8 3 0 0 3 3 2 1 SAM domain (Sterile alpha motif) PH PF00169.29 KFQ92395.1 - 6.6e-15 55.5 5.7 1.5e-14 54.3 4.2 2.4 2 0 0 2 2 2 1 PH domain SAM_2 PF07647.17 KFQ92395.1 - 4.8e-10 39.4 0.7 3.2e-09 36.7 0.3 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PDZ PF00595.24 KFQ92395.1 - 5e-09 36.4 0.1 1.5e-08 34.9 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFQ92395.1 - 3.7e-08 33.1 0.0 1e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PH_9 PF15410.6 KFQ92395.1 - 0.00051 20.4 2.4 0.15 12.4 2.9 3.5 3 1 0 3 3 3 1 Pleckstrin homology domain PDZ_2 PF13180.6 KFQ92395.1 - 0.002 18.4 0.2 0.033 14.5 0.0 2.6 2 0 0 2 2 2 1 PDZ domain PH_13 PF16652.5 KFQ92395.1 - 0.37 10.6 3.6 0.15 11.9 0.2 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Opi1 PF08618.10 KFQ92395.1 - 0.78 8.9 6.6 0.098 11.9 2.0 1.7 2 0 0 2 2 2 0 Transcription factor Opi1 PH_11 PF15413.6 KFQ92395.1 - 2.9 8.4 19.6 0.11 13.0 10.6 3.3 3 1 0 3 3 3 0 Pleckstrin homology domain ATG11 PF10377.9 KFQ92395.1 - 4.7 7.3 8.5 0.077 13.1 0.7 2.0 2 0 0 2 2 1 0 Autophagy-related protein 11 Adaptin_binding PF10199.9 KFQ92395.1 - 5 7.7 9.3 51 4.5 0.0 3.0 1 1 1 2 2 1 0 Alpha and gamma adaptin binding protein p34 Yae1_N PF09811.9 KFQ92397.1 - 9.5e-15 54.0 50.5 1.8e+04 -15.4 50.5 5.1 1 1 0 1 1 1 0 Essential protein Yae1, N terminal RVT_1 PF00078.27 KFQ92398.1 - 0.014 14.9 0.0 0.037 13.5 0.0 1.6 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) eIF-1a PF01176.19 KFQ92399.1 - 1.4e-21 76.0 0.1 1.8e-21 75.7 0.1 1.1 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 MAP7 PF05672.11 KFQ92400.1 - 3.5e-47 160.1 88.4 3.5e-47 160.1 88.4 3.3 3 0 0 3 3 3 2 MAP7 (E-MAP-115) family THRAP3_BCLAF1 PF15440.6 KFQ92401.1 - 1.5e-75 255.6 10.9 1.7e-75 255.4 10.9 1.0 1 0 0 1 1 1 1 THRAP3/BCLAF1 family PDCD7 PF16021.5 KFQ92401.1 - 0.021 13.9 0.5 0.028 13.6 0.5 1.1 1 0 0 1 1 1 0 Programmed cell death protein 7 Sa_NUDIX PF18167.1 KFQ92401.1 - 0.068 13.0 0.9 0.13 12.0 0.4 1.7 1 1 0 2 2 2 0 SMODS-associated NUDIX domain TMEM214 PF10151.9 KFQ92401.1 - 0.12 10.9 0.0 0.43 9.0 0.1 1.7 2 0 0 2 2 2 0 TMEM214, C-terminal, caspase 4 activator SH3_9 PF14604.6 KFQ92402.1 - 1.9e-54 181.3 2.8 3.6e-17 62.0 0.1 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 KFQ92402.1 - 3.8e-43 144.8 7.7 6.8e-15 54.4 0.4 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 KFQ92402.1 - 9e-42 140.6 3.7 3e-13 49.2 0.1 3.4 3 0 0 3 3 3 3 Variant SH3 domain XFP PF03894.15 KFQ92402.1 - 0.00023 21.0 0.0 1.8 8.2 0.0 3.2 2 1 1 3 3 3 2 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Tmemb_cc2 PF10267.9 KFQ92402.1 - 0.0042 16.3 0.5 0.0066 15.6 0.5 1.3 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein TrkA_C PF02080.21 KFQ92402.1 - 0.24 11.2 1.3 5.1 7.0 0.1 2.9 3 0 0 3 3 3 0 TrkA-C domain COG2 PF06148.11 KFQ92402.1 - 0.35 10.9 3.4 0.7 10.0 3.4 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4071 PF13281.6 KFQ92403.1 - 1.5e-163 544.2 1.9 1.5e-163 544.2 1.9 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4071) Pkinase PF00069.25 KFQ92403.1 - 1.4e-64 218.0 0.0 3.1e-64 216.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ92403.1 - 1.1e-41 142.8 0.0 2.4e-41 141.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFQ92403.1 - 0.00094 18.1 0.0 0.0028 16.5 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KFQ92403.1 - 0.0022 17.4 0.5 0.011 15.1 0.0 2.3 2 0 0 2 2 2 1 Kinase-like TPD52 PF04201.15 KFQ92403.1 - 1.5 8.4 9.6 0.6 9.7 3.4 2.9 3 0 0 3 3 3 0 Tumour protein D52 family E1_dh PF00676.20 KFQ92404.1 - 9.1e-124 412.3 0.0 1.1e-123 412.0 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KFQ92404.1 - 0.021 14.0 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase 7tm_2 PF00002.24 KFQ92406.1 - 3.1e-56 190.4 23.6 7.2e-56 189.2 23.6 1.7 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 KFQ92406.1 - 2.8e-17 62.9 4.4 2.8e-17 62.9 4.4 2.4 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif ASFV_J13L PF05568.11 KFQ92406.1 - 3 7.6 7.2 14 5.3 0.3 2.7 2 1 0 2 2 2 0 African swine fever virus J13L protein Glyco_hydro_15 PF00723.21 KFQ92407.1 - 1.7e-181 603.9 0.0 2.3e-181 603.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Metallophos PF00149.28 KFQ92408.1 - 2.7e-27 96.6 0.1 9.9e-27 94.8 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.32 KFQ92408.1 - 2.4e-18 64.2 1.6 2.4e-05 23.5 0.2 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KFQ92408.1 - 2.4e-16 60.0 2.9 8.2e-09 35.8 2.1 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFQ92408.1 - 2.7e-15 54.9 1.0 0.00079 19.2 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KFQ92408.1 - 1.4e-13 49.6 0.2 0.00049 19.5 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KFQ92408.1 - 1.7e-08 34.2 1.1 0.004 17.0 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain pair PPP5 PF08321.12 KFQ92408.1 - 2e-06 28.0 0.0 6.7e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 PPP5 TPR repeat region DUF1515 PF07439.11 KFQ92408.1 - 0.0095 16.0 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1515) SPARC_Ca_bdg PF10591.9 KFQ92408.1 - 0.16 12.3 0.0 7.4 6.9 0.1 2.7 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Adenine_deam_C PF13382.6 KFQ92408.1 - 0.18 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Adenine deaminase C-terminal domain EF-hand_4 PF12763.7 KFQ92408.1 - 0.91 9.5 2.5 11 6.1 0.3 3.0 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand IQ PF00612.27 KFQ92408.1 - 1.9 8.5 3.8 0.72 9.8 0.8 2.0 2 0 0 2 2 2 0 IQ calmodulin-binding motif F5_F8_type_C PF00754.25 KFQ92409.1 - 1.6e-30 105.9 0.7 1.6e-30 105.9 0.7 1.4 2 0 0 2 2 2 1 F5/8 type C domain KorB_C PF06613.11 KFQ92409.1 - 0.00097 19.1 0.3 0.0053 16.7 0.0 2.0 2 0 0 2 2 2 1 KorB C-terminal beta-barrel domain Pkinase PF00069.25 KFQ92410.1 - 3e-74 249.7 0.0 4.9e-74 249.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ92410.1 - 2e-34 119.1 0.0 3.4e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFQ92410.1 - 9.4e-05 21.5 0.5 0.00021 20.4 0.5 1.6 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KFQ92410.1 - 0.0017 18.0 0.3 1.2 8.7 0.0 2.6 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KFQ92410.1 - 0.005 16.5 0.8 0.012 15.2 0.8 1.6 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KFQ92410.1 - 0.4 9.4 0.0 0.4 9.4 0.0 2.6 3 0 0 3 3 3 0 Fungal protein kinase SOBP PF15279.6 KFQ92411.1 - 1.6e-08 35.6 38.3 1.8e-07 32.1 38.3 2.4 1 1 0 1 1 1 1 Sine oculis-binding protein DUF4694 PF15765.5 KFQ92411.1 - 0.025 14.6 0.1 0.098 12.7 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4694) BEN PF10523.9 KFQ92412.1 - 2.8e-25 88.3 0.2 1.2e-11 44.7 0.0 2.5 2 0 0 2 2 2 2 BEN domain Nuc_recep-AF1 PF11825.8 KFQ92412.1 - 0.0052 16.8 7.5 0.064 13.3 0.1 2.6 2 0 0 2 2 2 2 Nuclear/hormone receptor activator site AF-1 DUF1647 PF07801.11 KFQ92412.1 - 0.043 13.6 0.0 6.3 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) HJURP_C PF12347.8 KFQ92412.1 - 0.098 12.7 0.6 0.24 11.5 0.0 2.0 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat NHS PF15273.6 KFQ92413.1 - 2.4e-216 720.7 46.4 2.4e-216 720.7 46.4 2.2 2 0 0 2 2 2 1 NHS-like RVT_1 PF00078.27 KFQ92414.1 - 0.0024 17.4 0.0 0.0055 16.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) EF-hand_4 PF12763.7 KFQ92415.1 - 2e-13 50.2 0.0 4.5e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 KFQ92415.1 - 0.014 15.8 0.0 0.032 14.7 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 KFQ92415.1 - 0.025 14.1 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.6 KFQ92415.1 - 0.067 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair CHDCT2 PF08074.11 KFQ92415.1 - 0.17 12.0 0.7 0.43 10.7 0.7 1.6 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Lectin_N PF03954.14 KFQ92415.1 - 1.4 8.7 4.6 9 6.1 0.2 2.5 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain CAF1C_H4-bd PF12265.8 KFQ92416.1 - 3e-27 94.7 1.2 2.7e-26 91.6 0.4 2.7 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KFQ92416.1 - 1.7e-26 91.9 15.8 3.2e-07 30.9 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ92416.1 - 1.2e-05 25.5 0.7 0.0051 17.1 0.1 3.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFQ92416.1 - 7.7e-05 22.7 0.2 0.017 15.0 0.0 2.9 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Capsid_NCLDV PF04451.12 KFQ92416.1 - 0.077 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein Taxilin PF09728.9 KFQ92417.1 - 1.5e-117 392.2 75.4 1.7e-117 392.0 75.4 1.0 1 0 0 1 1 1 1 Myosin-like coiled-coil protein HTH_26 PF13443.6 KFQ92417.1 - 0.057 13.9 1.5 0.35 11.3 0.0 3.1 3 1 0 3 3 3 0 Cro/C1-type HTH DNA-binding domain STOP PF05217.12 KFQ92417.1 - 0.072 13.4 0.5 0.3 11.4 0.5 2.2 1 0 0 1 1 1 0 STOP protein Metallothio_2 PF01439.18 KFQ92417.1 - 0.69 10.8 1.6 11 7.0 0.1 2.7 2 0 0 2 2 2 0 Metallothionein APG6_N PF17675.1 KFQ92417.1 - 3.8 8.0 73.4 2.5 8.6 25.7 3.8 1 1 3 4 4 4 0 Apg6 coiled-coil region BSD PF03909.17 KFQ92418.1 - 1.9e-13 50.2 1.3 1.9e-13 50.2 1.3 3.6 4 1 1 5 5 5 1 BSD domain RlaP PF10127.9 KFQ92418.1 - 0.1 12.2 3.6 0.22 11.1 3.6 1.6 1 0 0 1 1 1 0 RNA repair pathway DNA polymerase beta family CCDC84 PF14968.6 KFQ92418.1 - 7.3 6.1 15.0 1.1 8.8 0.7 2.8 1 1 1 3 3 3 0 Coiled coil protein 84 DUF4462 PF14692.6 KFQ92419.1 - 0.11 12.0 0.2 0.17 11.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) 7tm_1 PF00001.21 KFQ92421.1 - 2.3e-55 187.8 13.6 2.9e-55 187.4 13.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ92421.1 - 2.8e-10 40.0 12.4 5e-10 39.2 12.3 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 KFQ92421.1 - 1e-09 38.2 9.7 1.9e-09 37.3 9.7 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFQ92421.1 - 0.00053 19.8 14.0 0.0011 18.7 14.0 1.6 1 1 0 1 1 1 1 Olfactory receptor Clat_adaptor_s PF01217.20 KFQ92422.1 - 2.2e-60 202.7 2.2 2.6e-60 202.5 2.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF629 PF04780.12 KFQ92422.1 - 0.002 16.7 0.3 0.0026 16.4 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF629) PulA_N1 PF17999.1 KFQ92422.1 - 0.07 13.9 0.1 0.13 13.1 0.1 1.4 1 0 0 1 1 1 0 Pullulanase N1-terminal domain zf-CCCH PF00642.24 KFQ92423.1 - 9.8e-13 47.7 13.0 1.6e-06 27.9 4.2 2.8 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFQ92423.1 - 3e-06 27.1 13.6 0.0002 21.3 2.3 2.7 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KFQ92423.1 - 7e-06 25.7 12.4 0.00047 19.9 4.3 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger RRM_1 PF00076.22 KFQ92423.1 - 9.1e-05 22.2 0.0 0.00021 21.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFQ92423.1 - 0.0056 16.7 0.1 0.012 15.7 0.1 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Torus PF16131.5 KFQ92423.1 - 0.015 16.0 0.3 0.015 16.0 0.3 4.4 3 2 1 4 4 4 0 Torus domain DUF3430 PF11912.8 KFQ92423.1 - 0.11 12.5 0.6 0.17 11.9 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) Collectrin PF16959.5 KFQ92424.1 - 1.4e-69 232.8 0.5 2.1e-69 232.2 0.5 1.2 1 0 0 1 1 1 1 Renal amino acid transporter MscL PF01741.18 KFQ92424.1 - 0.0099 16.2 0.1 0.016 15.5 0.1 1.4 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL ECF_trnsprt PF12822.7 KFQ92424.1 - 0.024 14.7 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Pilin_N PF07790.11 KFQ92424.1 - 0.047 14.6 0.1 0.37 11.7 0.0 2.2 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal DUF5305 PF17231.2 KFQ92424.1 - 0.051 13.0 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF2140 PF09911.9 KFQ92424.1 - 0.057 13.0 0.1 0.25 10.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) CcmH PF03918.14 KFQ92424.1 - 0.061 12.6 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Cytochrome C biogenesis protein UPF0524 PF15823.5 KFQ92424.1 - 0.086 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 UPF0524 of C3orf70 EphA2_TM PF14575.6 KFQ92424.1 - 0.087 13.7 0.1 0.24 12.3 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Glycophorin_A PF01102.18 KFQ92424.1 - 0.095 12.9 0.0 0.31 11.3 0.0 1.8 2 0 0 2 2 2 0 Glycophorin A OAD_gamma PF04277.13 KFQ92424.1 - 0.11 13.1 0.0 0.21 12.2 0.0 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain PetG PF02529.15 KFQ92424.1 - 0.12 12.3 0.2 0.21 11.4 0.2 1.3 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 DUF4381 PF14316.6 KFQ92424.1 - 0.17 12.2 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Peptidase_M2 PF01401.18 KFQ92425.1 - 5.4e-224 745.0 4.4 6.7e-224 744.7 4.4 1.1 1 0 0 1 1 1 1 Angiotensin-converting enzyme Collectrin PF16959.5 KFQ92425.1 - 4.5e-72 240.8 0.3 8e-72 240.0 0.3 1.4 1 0 0 1 1 1 1 Renal amino acid transporter Peptidase_M3 PF01432.20 KFQ92425.1 - 0.018 14.4 3.3 0.71 9.1 0.0 2.9 4 0 0 4 4 4 0 Peptidase family M3 Pkinase_Tyr PF07714.17 KFQ92426.1 - 2e-87 292.8 0.0 2.8e-87 292.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ92426.1 - 7.2e-41 140.3 0.0 1.3e-40 139.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFQ92426.1 - 3.3e-22 78.3 0.5 7.8e-22 77.2 0.5 1.7 1 0 0 1 1 1 1 SH2 domain PH PF00169.29 KFQ92426.1 - 5.6e-18 65.4 1.0 1.2e-17 64.3 0.2 2.0 2 0 0 2 2 2 1 PH domain BTK PF00779.19 KFQ92426.1 - 8.6e-13 47.9 4.1 1.6e-12 47.0 4.1 1.5 1 0 0 1 1 1 1 BTK motif SH3_9 PF14604.6 KFQ92426.1 - 1.2e-08 34.7 0.6 3.2e-08 33.3 0.2 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFQ92426.1 - 1.1e-07 31.4 0.1 3.9e-07 29.6 0.1 2.1 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFQ92426.1 - 1.7e-05 24.4 0.0 4.3e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Haspin_kinase PF12330.8 KFQ92426.1 - 0.0003 19.9 0.0 0.00054 19.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain PH_8 PF15409.6 KFQ92426.1 - 0.0068 16.7 0.9 0.068 13.5 0.2 2.8 3 0 0 3 3 3 1 Pleckstrin homology domain SH3_3 PF08239.11 KFQ92426.1 - 0.02 15.2 0.2 0.051 13.9 0.2 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain SH3_4 PF06347.13 KFQ92426.1 - 0.039 13.8 0.1 0.081 12.8 0.1 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain PH_11 PF15413.6 KFQ92426.1 - 0.069 13.6 2.6 0.076 13.5 0.3 2.3 2 1 0 2 2 2 0 Pleckstrin homology domain Kinase-like PF14531.6 KFQ92426.1 - 0.071 12.4 0.2 0.32 10.2 0.0 2.0 2 0 0 2 2 2 0 Kinase-like PH_3 PF14593.6 KFQ92426.1 - 0.086 13.0 0.7 0.34 11.0 0.1 2.3 2 0 0 2 2 2 0 PH domain SH3_10 PF17902.1 KFQ92426.1 - 0.15 12.2 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 SH3 domain PDGF PF00341.17 KFQ92427.1 - 1e-22 80.2 9.5 1e-22 80.2 9.5 2.3 2 1 0 2 2 2 1 PDGF/VEGF domain CXCXC PF03128.14 KFQ92427.1 - 0.049 14.1 4.3 0.049 14.1 4.3 6.5 6 0 0 6 6 6 0 CXCXC repeat Ank_2 PF12796.7 KFQ92428.1 - 1.9e-33 114.9 7.6 5.8e-13 49.2 0.2 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ92428.1 - 4.3e-31 106.9 7.7 7.9e-10 39.1 0.2 4.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ92428.1 - 4.9e-27 91.0 3.3 0.002 18.4 0.0 6.9 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KFQ92428.1 - 1.8e-25 88.6 7.3 3.9e-06 27.0 0.1 5.6 1 1 5 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KFQ92428.1 - 1.2e-23 82.4 9.4 0.0019 18.6 0.2 7.0 7 0 0 7 7 7 6 Ankyrin repeat SOCS_box PF07525.16 KFQ92428.1 - 2.6e-11 43.7 4.4 5.6e-11 42.6 4.4 1.6 1 0 0 1 1 1 1 SOCS box DUF1843 PF08898.10 KFQ92428.1 - 0.12 12.8 0.1 7.9 7.1 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1843) Nucleotid_trans PF03407.16 KFQ92428.1 - 0.22 11.5 0.0 0.73 9.8 0.0 1.8 2 0 0 2 2 2 0 Nucleotide-diphospho-sugar transferase Ank_4 PF13637.6 KFQ92429.1 - 1.8e-30 104.9 10.1 1.5e-08 35.0 0.1 4.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFQ92429.1 - 2.9e-30 104.7 3.2 2.4e-14 53.7 0.4 3.7 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFQ92429.1 - 5e-26 87.9 4.5 0.0032 17.9 0.1 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 KFQ92429.1 - 1.2e-24 85.6 10.2 0.0012 19.2 0.1 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 KFQ92429.1 - 1.1e-17 63.9 6.1 0.001 19.3 0.1 5.5 1 1 5 6 6 6 6 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFQ92429.1 - 2.3e-06 27.9 3.4 4.1e-06 27.0 3.4 1.5 1 0 0 1 1 1 1 SOCS box CRAL_TRIO PF00650.20 KFQ92430.1 - 2.7e-28 98.7 0.2 4.8e-28 97.9 0.2 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Motile_Sperm PF00635.26 KFQ92430.1 - 5.4e-21 74.5 0.0 1.3e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 MSP (Major sperm protein) domain CRAL_TRIO_2 PF13716.6 KFQ92430.1 - 0.03 14.5 0.1 0.067 13.4 0.1 1.6 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain YLP PF02757.17 KFQ92430.1 - 2.9 8.1 4.5 4 7.7 0.4 2.5 2 0 0 2 2 2 0 YLP motif Neur_chan_LBD PF02931.23 KFQ92432.1 - 1.9e-52 177.8 0.0 2.5e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFQ92432.1 - 1.9e-40 139.4 0.2 7.1e-34 117.9 0.0 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region GEMIN8 PF15348.6 KFQ92434.1 - 2e-95 319.5 15.2 2.2e-95 319.4 15.2 1.0 1 0 0 1 1 1 1 Gemini of Cajal bodies-associated protein 8 Myelin_PLP PF01275.19 KFQ92435.1 - 1e-99 333.2 18.6 1.2e-99 333.0 18.6 1.0 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) PspB PF06667.12 KFQ92435.1 - 0.074 13.1 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Phage shock protein B LapA_dom PF06305.11 KFQ92435.1 - 0.15 11.9 1.6 0.36 10.7 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Saf_2TM PF18303.1 KFQ92435.1 - 0.28 10.7 3.2 0.67 9.5 0.6 2.5 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain Sedlin_N PF04628.13 KFQ92436.1 - 1.9e-48 163.9 0.4 2.2e-48 163.7 0.4 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KFQ92436.1 - 2.2e-09 37.4 0.1 2.8e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 Sybindin-like family Suv3_N PF18114.1 KFQ92436.1 - 0.026 14.6 0.1 0.032 14.3 0.1 1.1 1 0 0 1 1 1 0 Suv3 helical N-terminal domain Ras PF00071.22 KFQ92437.1 - 3.3e-57 192.6 0.0 3.8e-57 192.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ92437.1 - 4.1e-30 104.4 0.0 6.5e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ92437.1 - 1.2e-11 44.4 0.0 1.4e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFQ92437.1 - 6.4e-06 26.2 0.0 1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFQ92437.1 - 6.6e-05 22.9 0.0 0.011 15.6 0.1 2.3 2 1 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 KFQ92437.1 - 0.00015 21.2 0.0 0.00018 20.9 0.0 1.2 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 KFQ92437.1 - 0.0051 16.6 0.2 0.028 14.2 0.0 1.9 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 KFQ92437.1 - 0.0085 15.8 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KFQ92437.1 - 0.02 14.4 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KFQ92437.1 - 0.022 15.1 0.0 0.031 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 KFQ92437.1 - 0.023 13.9 2.3 0.59 9.2 0.1 2.5 1 1 1 2 2 2 0 G-protein alpha subunit GTP_EFTU PF00009.27 KFQ92437.1 - 0.03 13.9 0.0 0.1 12.1 0.0 1.8 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KFQ92437.1 - 0.14 11.6 0.0 0.36 10.3 0.0 1.6 2 1 1 3 3 3 0 Ferrous iron transport protein B AAA_22 PF13401.6 KFQ92437.1 - 0.19 12.0 0.0 0.94 9.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain TFIIS_M PF07500.14 KFQ92438.1 - 1.2e-27 96.6 3.2 1.2e-27 96.6 3.2 2.0 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain Med26 PF08711.11 KFQ92438.1 - 3.8e-10 39.6 0.4 1.3e-09 37.9 0.1 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain TFIIS_C PF01096.18 KFQ92438.1 - 0.0066 16.3 5.6 0.0088 15.9 0.2 2.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Ribosomal_L37e PF01907.19 KFQ92438.1 - 0.41 10.9 3.7 3.3 8.0 0.3 2.5 2 0 0 2 2 2 0 Ribosomal protein L37e MutS_III PF05192.18 KFQ92438.1 - 0.95 9.7 5.2 1.6 8.9 5.0 1.7 1 1 0 1 1 1 0 MutS domain III EGF_CA PF07645.15 KFQ92439.1 - 1.1e-23 83.1 40.5 6.6e-11 42.2 10.7 6.1 4 2 1 5 5 5 3 Calcium-binding EGF domain MAM PF00629.23 KFQ92439.1 - 1.4e-20 73.8 0.0 2.8e-20 72.8 0.0 1.5 1 1 0 1 1 1 1 MAM domain, meprin/A5/mu cEGF PF12662.7 KFQ92439.1 - 7.4e-18 64.1 38.3 3.5e-05 23.6 0.5 5.8 5 0 0 5 5 5 5 Complement Clr-like EGF-like EGF_3 PF12947.7 KFQ92439.1 - 1.6e-11 44.2 24.3 3.2e-10 40.0 12.6 6.4 5 1 0 5 5 5 3 EGF domain EGF PF00008.27 KFQ92439.1 - 3.9e-10 39.8 75.3 8.2e-05 22.8 5.5 6.3 6 0 0 6 6 6 4 EGF-like domain FXa_inhibition PF14670.6 KFQ92439.1 - 6.9e-10 39.0 77.7 7.6e-06 26.1 8.7 5.6 3 1 2 5 5 5 4 Coagulation Factor Xa inhibitory site hEGF PF12661.7 KFQ92439.1 - 0.0026 18.3 1.7 0.0026 18.3 1.7 7.6 7 0 0 7 7 7 3 Human growth factor-like EGF CENP-B_dimeris PF09026.10 KFQ92439.1 - 0.81 10.1 5.1 2.4 8.6 2.4 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain LRR_8 PF13855.6 KFQ92440.1 - 7.9e-75 246.5 100.0 8.9e-11 41.4 9.8 14.2 8 4 6 15 15 15 15 Leucine rich repeat LRR_4 PF12799.7 KFQ92440.1 - 2.9e-35 119.7 105.1 1.1e-05 25.7 2.6 15.2 6 4 6 15 15 15 14 Leucine Rich repeats (2 copies) TIR PF01582.20 KFQ92440.1 - 6.5e-17 61.9 0.1 1.1e-16 61.2 0.1 1.3 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.6 KFQ92440.1 - 1.1e-13 51.0 41.7 0.0001 21.9 6.4 8.1 3 2 5 9 9 9 6 Leucine-rich repeat LRR_5 PF13306.6 KFQ92440.1 - 2.5e-13 50.1 29.2 2.2e-06 27.6 0.2 6.9 4 1 2 7 7 7 4 BspA type Leucine rich repeat region (6 copies) LRR_12 PF18837.1 KFQ92440.1 - 7.4e-12 44.7 0.2 7.4e-12 44.7 0.2 4.5 5 0 0 5 5 5 1 Leucine-rich repeat LRR_1 PF00560.33 KFQ92440.1 - 1.4e-10 40.2 89.6 2.8 8.8 0.0 21.1 19 6 4 23 23 23 8 Leucine Rich Repeat TIR_2 PF13676.6 KFQ92440.1 - 2.3e-08 34.7 0.1 8.7e-08 32.8 0.1 2.0 2 0 0 2 2 2 1 TIR domain LRR_6 PF13516.6 KFQ92440.1 - 0.022 14.8 78.6 0.82 9.9 0.0 17.7 20 0 0 20 20 20 0 Leucine Rich repeat Pribosyl_synth PF14572.6 KFQ92441.1 - 9.3e-45 152.9 2.1 3.6e-37 128.2 0.7 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KFQ92441.1 - 2.1e-33 114.7 0.3 1.2e-32 112.2 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KFQ92441.1 - 1.7e-13 50.4 0.2 3.3e-13 49.5 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KFQ92441.1 - 0.00036 20.1 0.1 0.00057 19.4 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF3247 PF11607.8 KFQ92441.1 - 0.16 12.3 0.1 0.35 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) FERM_M PF00373.18 KFQ92442.1 - 3.1e-18 66.3 0.1 9.3e-18 64.8 0.1 1.9 1 0 0 1 1 1 1 FERM central domain PDZ PF00595.24 KFQ92442.1 - 1.6e-10 41.1 0.0 3.6e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFQ92442.1 - 1.6e-07 31.1 0.1 3.7e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFQ92442.1 - 5e-05 23.5 0.1 0.00019 21.7 0.0 2.0 2 0 0 2 2 2 1 PDZ domain WW PF00397.26 KFQ92442.1 - 0.0013 18.7 0.1 0.0031 17.6 0.1 1.7 1 0 0 1 1 1 1 WW domain FERM_f0 PF16511.5 KFQ92442.1 - 0.0035 17.6 0.0 0.0083 16.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM Vfa1 PF08432.10 KFQ92442.1 - 0.098 13.0 8.2 0.052 13.9 1.8 2.8 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 MRG PF05712.13 KFQ92443.1 - 7.2e-70 234.3 0.5 1.1e-69 233.8 0.5 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KFQ92443.1 - 4e-05 23.4 0.4 0.0001 22.1 0.4 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 KFQ92443.1 - 0.018 15.0 0.2 0.046 13.6 0.2 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DNA_pol_phi PF04931.13 KFQ92443.1 - 3.8 5.5 13.1 5.6 4.9 13.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi RhoGAP PF00620.27 KFQ92444.1 - 8.9e-48 162.0 0.0 1.8e-47 160.9 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain DUF1679 PF07914.11 KFQ92444.1 - 0.055 12.3 0.0 0.09 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) COS PF18568.1 KFQ92445.1 - 2.5e-34 117.0 2.4 3.1e-34 116.7 0.8 2.1 3 0 0 3 3 3 1 TRIM C-terminal subgroup One Signature domain SPRY PF00622.28 KFQ92445.1 - 5.7e-17 61.9 0.0 1.1e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 SPRY domain PRY PF13765.6 KFQ92445.1 - 7.3e-13 47.9 0.0 2.8e-12 46.0 0.0 2.1 1 0 0 1 1 1 1 SPRY-associated domain zf-B_box PF00643.24 KFQ92445.1 - 3.5e-09 36.7 0.8 3.5e-09 36.7 0.8 5.1 5 1 0 5 5 3 2 B-box zinc finger fn3 PF00041.21 KFQ92445.1 - 3.2e-08 33.8 0.2 6.7e-08 32.8 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III domain zf-RING_UBOX PF13445.6 KFQ92445.1 - 4.1e-07 29.9 9.6 4.1e-07 29.9 9.6 4.0 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFQ92445.1 - 1.2e-06 28.3 7.5 1.2e-06 28.3 7.5 4.3 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ92445.1 - 3.6e-06 26.7 11.6 3.6e-06 26.7 11.6 4.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFQ92445.1 - 9.4e-06 25.7 12.3 9.4e-06 25.7 12.3 5.4 5 1 1 6 6 6 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KFQ92445.1 - 1.1e-05 25.2 7.1 1.1e-05 25.2 7.1 5.0 5 1 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ92445.1 - 7.7e-05 22.9 11.4 7.7e-05 22.9 11.4 3.8 4 0 0 4 4 3 2 Ring finger domain zf-RING_5 PF14634.6 KFQ92445.1 - 0.0017 18.3 9.9 0.0017 18.3 9.9 4.5 4 1 0 4 4 3 1 zinc-RING finger domain Pur_ac_phosph_N PF16656.5 KFQ92445.1 - 0.0076 16.8 0.2 0.019 15.6 0.2 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain fn3_4 PF16794.5 KFQ92445.1 - 0.061 13.2 0.0 0.26 11.2 0.0 2.0 3 0 0 3 3 3 0 Fibronectin-III type domain Serine_rich PF08824.10 KFQ92445.1 - 0.32 11.0 7.6 3.3 7.7 7.5 2.2 1 1 0 1 1 1 0 Serine rich protein interaction domain Baculo_PEP_C PF04513.12 KFQ92445.1 - 0.37 10.8 6.2 0.099 12.7 0.7 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Voltage_CLC PF00654.20 KFQ92446.1 - 1.5e-106 356.7 18.0 1.5e-106 356.7 18.0 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KFQ92446.1 - 2.6e-13 50.2 0.7 6.5e-07 29.7 0.1 2.5 2 0 0 2 2 2 2 CBS domain C2 PF00168.30 KFQ92447.1 - 0.00032 20.9 0.0 0.00076 19.7 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF4055 PF13264.6 KFQ92447.1 - 5.7 7.1 8.1 3.3 7.9 0.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4055) Claudin_2 PF13903.6 KFQ92448.1 - 5.3e-14 52.4 8.3 6.5e-14 52.1 8.3 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFQ92448.1 - 2.6e-06 27.4 11.1 4.2e-06 26.7 11.1 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family HIG_1_N PF04588.13 KFQ92448.1 - 2 8.7 10.4 6.8 7.0 0.2 3.6 3 0 0 3 3 3 0 Hypoxia induced protein conserved region ASD2 PF08687.11 KFQ92449.1 - 3.9e-120 400.8 26.1 3.9e-120 400.8 26.1 3.8 3 0 0 3 3 3 1 Apx/Shroom domain ASD2 ASD1 PF08688.10 KFQ92449.1 - 6.9e-58 195.9 6.0 6.9e-58 195.9 6.0 5.3 5 2 0 5 5 5 1 Apx/Shroom domain ASD1 Ocular_alb PF02101.15 KFQ92450.1 - 1.4e-203 676.2 7.6 1.7e-203 676.0 7.6 1.0 1 0 0 1 1 1 1 Ocular albinism type 1 protein 7tm_2 PF00002.24 KFQ92450.1 - 0.00012 21.5 8.3 0.00012 21.5 8.3 1.6 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) WD40 PF00400.32 KFQ92451.1 - 7.1e-53 175.4 27.6 1.7e-10 41.3 0.2 8.5 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ92451.1 - 1.2e-30 105.7 1.7 7.2e-09 35.8 0.0 5.9 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFQ92451.1 - 3.2e-11 43.5 0.5 0.0016 18.3 0.1 3.5 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFQ92451.1 - 1.1e-05 24.5 1.3 0.083 11.8 0.0 3.4 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFQ92451.1 - 0.00021 20.7 0.0 1.2 8.4 0.0 3.2 4 1 0 4 4 4 2 WD40-like domain Nup160 PF11715.8 KFQ92451.1 - 0.025 13.2 4.5 0.27 9.8 0.0 3.5 2 2 3 5 5 5 0 Nucleoporin Nup120/160 PD40 PF07676.12 KFQ92451.1 - 0.038 13.9 0.0 0.28 11.2 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Glyco_hydro_11 PF00457.17 KFQ92451.1 - 0.081 12.6 1.2 2.8 7.6 0.1 2.7 2 0 0 2 2 2 0 Glycosyl hydrolases family 11 IKI3 PF04762.12 KFQ92451.1 - 0.083 10.9 0.4 1.2 7.0 0.0 2.4 2 1 1 3 3 3 0 IKI3 family BTB PF00651.31 KFQ92452.1 - 8.2e-24 84.0 1.4 8.2e-17 61.4 0.3 3.4 3 0 0 3 3 3 2 BTB/POZ domain Ras PF00071.22 KFQ92452.1 - 5.3e-06 26.1 0.0 1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Ras family Rieske_2 PF13806.6 KFQ92453.1 - 7.2e-08 32.3 0.0 9.3e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 KFQ92453.1 - 2.5e-07 30.5 0.0 3.9e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PAF PF15715.5 KFQ92453.1 - 0.078 13.6 0.1 0.12 12.9 0.1 1.3 1 0 0 1 1 1 0 PCNA-associated factor histone like domain Sulfatase PF00884.23 KFQ92454.1 - 2.2e-43 148.8 0.2 4e-43 148.0 0.2 1.4 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 KFQ92454.1 - 8.8e-06 24.6 0.2 9.9e-05 21.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF229) DUF4994 PF16385.5 KFQ92454.1 - 1.8e-05 24.6 0.3 0.00063 19.6 0.0 2.9 2 1 0 2 2 2 1 Domain of unknown function DUF4976 PF16347.5 KFQ92454.1 - 8.2e-05 22.8 0.0 0.00027 21.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Metalloenzyme PF01676.18 KFQ92454.1 - 0.0001 21.8 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 KFQ92454.1 - 0.00097 18.8 0.2 0.0092 15.6 0.0 2.3 3 0 0 3 3 3 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.12 KFQ92454.1 - 0.034 13.2 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) COX_ARM PF06481.14 KFQ92454.1 - 0.11 12.4 0.8 0.25 11.3 0.2 1.9 2 0 0 2 2 2 0 COX Aromatic Rich Motif TPR_1 PF00515.28 KFQ92455.1 - 1.7e-46 154.2 69.0 7e-05 22.5 0.0 24.0 26 1 0 26 26 23 10 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ92455.1 - 8.5e-42 141.5 38.9 0.0008 19.9 1.2 16.2 16 1 1 17 17 15 9 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ92455.1 - 1.3e-40 134.3 85.1 0.00051 19.9 0.0 26.1 27 2 0 28 28 25 9 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ92455.1 - 9.4e-34 113.2 42.4 0.00034 21.2 0.4 21.8 16 5 8 24 24 20 5 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ92455.1 - 1.1e-33 115.6 22.9 4.1e-08 33.7 0.2 13.5 12 4 2 15 15 14 5 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ92455.1 - 5e-31 106.1 49.0 0.00063 19.4 0.0 18.8 18 2 2 20 20 18 8 TPR repeat TPR_8 PF13181.6 KFQ92455.1 - 1.6e-29 99.6 65.7 0.0021 18.1 0.1 22.4 24 0 0 24 24 23 7 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ92455.1 - 2.9e-28 97.9 57.4 0.00016 21.9 0.2 16.0 14 4 4 18 18 15 10 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ92455.1 - 1.8e-25 87.4 43.9 0.0007 19.8 0.2 19.5 19 0 0 19 19 19 4 Tetratricopeptide repeat TPR_9 PF13371.6 KFQ92455.1 - 1.5e-14 53.9 14.7 0.0009 19.3 0.2 9.1 8 1 1 9 9 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ92455.1 - 5e-14 51.2 36.2 0.57 10.3 0.1 16.8 18 1 0 18 18 16 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFQ92455.1 - 4.4e-10 39.5 38.5 3.4 8.5 0.1 16.1 17 0 0 17 17 14 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ92455.1 - 4.1e-08 33.3 49.7 0.0025 18.0 0.7 10.6 7 3 4 11 11 11 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KFQ92455.1 - 4.5e-08 32.6 49.8 2.3e-06 27.0 5.5 8.4 5 2 3 8 8 8 2 Tetratricopeptide repeat RPN7 PF10602.9 KFQ92455.1 - 0.00013 21.7 14.0 4.2 7.1 4.1 8.4 6 3 1 8 8 8 1 26S proteasome subunit RPN7 TPR_21 PF09976.9 KFQ92455.1 - 0.00032 20.5 37.0 0.11 12.2 0.1 8.6 5 3 3 8 8 8 2 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 KFQ92455.1 - 0.00044 20.0 24.2 20 5.2 0.0 11.9 12 0 0 12 12 11 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 KFQ92455.1 - 0.0019 17.3 8.0 0.15 11.1 0.0 4.1 4 2 0 4 4 4 2 Coatomer WD associated region TPR_4 PF07721.14 KFQ92455.1 - 0.0025 18.3 0.3 3.4 8.6 0.0 4.9 3 0 0 3 3 2 1 Tetratricopeptide repeat BTAD PF03704.17 KFQ92455.1 - 0.0053 17.2 0.1 0.0053 17.2 0.1 5.8 5 1 1 6 6 6 1 Bacterial transcriptional activator domain TPR_20 PF14561.6 KFQ92455.1 - 0.048 14.0 18.8 0.65 10.4 0.0 8.6 9 1 1 10 10 8 0 Tetratricopeptide repeat TolB_N PF04052.13 KFQ92455.1 - 0.078 13.2 0.1 0.38 11.0 0.1 2.1 2 0 0 2 2 2 0 TolB amino-terminal domain HrpB1_HrpK PF09613.10 KFQ92455.1 - 0.15 11.7 13.2 1.8 8.2 0.0 6.2 6 1 1 7 7 7 0 Bacterial type III secretion protein (HrpB1_HrpK) SHNi-TPR PF10516.9 KFQ92455.1 - 0.18 11.3 0.9 53 3.4 0.1 4.2 4 0 0 4 4 4 0 SHNi-TPR DUF982 PF06169.12 KFQ92455.1 - 0.24 11.5 1.2 2.5 8.2 0.2 3.4 2 1 1 3 3 2 0 Protein of unknown function (DUF982) Imm71 PF15602.6 KFQ92455.1 - 0.38 10.8 2.9 1.1 9.3 0.1 3.3 3 0 0 3 3 3 0 Immunity protein 71 Retrotran_gag_2 PF14223.6 KFQ92455.1 - 0.41 10.3 14.2 0.24 11.0 0.1 4.7 3 1 1 4 4 4 0 gag-polypeptide of LTR copia-type DUF3856 PF12968.7 KFQ92455.1 - 0.84 9.7 10.1 49 4.0 0.1 6.2 4 3 1 5 5 5 0 Domain of Unknown Function (DUF3856) FlbT PF07378.11 KFQ92455.1 - 1.4 9.0 6.0 2.2 8.3 0.5 3.9 3 0 0 3 3 3 0 Flagellar protein FlbT CP12 PF02672.15 KFQ92455.1 - 3.2 8.6 7.7 35 5.2 0.5 4.4 3 0 0 3 3 2 0 CP12 domain HemY_N PF07219.13 KFQ92455.1 - 3.3 7.9 17.5 15 5.8 0.1 6.9 7 1 1 8 8 7 0 HemY protein N-terminus COG5 PF10392.9 KFQ92456.1 - 0.00069 19.8 16.9 0.0024 18.0 0.3 3.2 2 1 1 3 3 3 1 Golgi transport complex subunit 5 Baculo_PEP_C PF04513.12 KFQ92456.1 - 0.075 13.1 10.5 2.3 8.3 2.2 3.3 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bacillus_HBL PF05791.11 KFQ92456.1 - 0.13 12.1 0.2 0.13 12.1 0.2 3.3 1 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF1664 PF07889.12 KFQ92456.1 - 0.15 12.1 14.0 1.5 8.9 0.4 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) TrbI_Ftype PF09677.10 KFQ92456.1 - 0.92 9.9 3.1 6 7.2 0.4 2.5 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) Fib_alpha PF08702.10 KFQ92456.1 - 1.5 9.0 19.3 3.2 7.9 0.1 3.7 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family T3SS_needle_E PF08988.10 KFQ92456.1 - 1.8 8.8 9.4 4.6 7.5 0.1 3.3 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle Spore_II_R PF09551.10 KFQ92456.1 - 2 8.9 5.4 6.3 7.3 0.1 2.6 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) ING PF12998.7 KFQ92456.1 - 2.4 8.8 18.6 1.4 9.6 10.0 3.6 1 1 3 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding XhlA PF10779.9 KFQ92456.1 - 2.7 8.3 16.0 11 6.3 0.0 4.6 3 1 1 4 4 4 0 Haemolysin XhlA Helo_like_N PF17111.5 KFQ92456.1 - 3.8 6.8 15.2 3.1 7.1 10.1 2.5 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins RTT107_BRCT_5 PF16770.5 KFQ92457.1 - 2e-09 37.2 0.2 3.8e-09 36.3 0.2 1.4 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 KFQ92457.1 - 0.0017 18.7 0.4 0.03 14.7 0.2 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KFQ92457.1 - 0.011 16.0 0.0 4.9 7.5 0.0 2.3 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain NTPase_I-T PF01931.18 KFQ92458.1 - 1.9e-08 34.3 0.1 3.2e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF84 Cortexin PF11057.8 KFQ92459.1 - 1.4e-42 143.4 0.1 1.5e-42 143.3 0.1 1.0 1 0 0 1 1 1 1 Cortexin of kidney EGF_CA PF07645.15 KFQ92460.1 - 0 1033.7 742.7 8.4e-11 41.9 7.5 48.7 48 2 2 50 50 50 44 Calcium-binding EGF domain cEGF PF12662.7 KFQ92460.1 - 1.4e-215 696.3 429.8 3.3e-09 36.5 0.4 51.6 52 0 0 52 52 52 44 Complement Clr-like EGF-like TB PF00683.17 KFQ92460.1 - 9.8e-119 386.9 150.7 4.6e-16 58.3 10.8 11.4 9 0 0 9 9 9 9 TB domain EGF PF00008.27 KFQ92460.1 - 5.3e-114 371.9 704.6 5.7e-05 23.3 11.1 49.8 49 0 0 49 49 49 45 EGF-like domain FXa_inhibition PF14670.6 KFQ92460.1 - 2.4e-92 302.9 733.8 5.1e-08 33.1 10.0 49.7 45 5 5 50 50 50 40 Coagulation Factor Xa inhibitory site hEGF PF12661.7 KFQ92460.1 - 6.6e-76 248.6 688.3 0.00052 20.5 3.3 53.3 54 0 0 54 54 54 41 Human growth factor-like EGF EGF_3 PF12947.7 KFQ92460.1 - 2.4e-36 123.6 655.6 1.8e-08 34.4 11.6 50.6 48 3 2 50 50 50 36 EGF domain Fibrillin_U_N PF18193.1 KFQ92460.1 - 5.7e-19 67.9 7.8 5.7e-19 67.9 7.8 9.9 11 0 0 11 11 11 1 Fibrillin 1 unique N-terminal domain Plasmod_Pvs28 PF06247.11 KFQ92460.1 - 0.64 10.4 549.8 0.052 13.9 6.1 46.0 44 3 1 45 45 45 0 Pvs28 EGF domain Isochorismatase PF00857.20 KFQ92461.1 - 3.9e-26 92.3 0.0 6.2e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Pro_isomerase PF00160.21 KFQ92462.1 - 2.2e-45 154.8 0.1 2.4e-45 154.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PHO4 PF01384.20 KFQ92463.1 - 3.4e-142 473.5 4.0 4.1e-142 473.2 4.0 1.1 1 0 0 1 1 1 1 Phosphate transporter family CS PF04969.16 KFQ92464.1 - 7.2e-17 62.2 0.2 2e-16 60.8 0.2 1.8 1 0 0 1 1 1 1 CS domain DUF1737 PF08410.10 KFQ92464.1 - 0.15 11.9 0.1 0.36 10.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) Pkinase PF00069.25 KFQ92465.1 - 1.3e-60 205.0 0.0 3.5e-47 161.0 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain CaMKII_AD PF08332.10 KFQ92465.1 - 5.1e-31 107.5 0.0 8.8e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain Pkinase_Tyr PF07714.17 KFQ92465.1 - 2.3e-23 82.8 0.0 5.2e-18 65.3 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase SnoaL_3 PF13474.6 KFQ92465.1 - 0.00087 19.6 0.0 0.0016 18.7 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KFQ92465.1 - 0.0014 19.0 0.0 0.0027 18.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Pkinase_fungal PF17667.1 KFQ92465.1 - 0.0039 16.0 0.0 0.0058 15.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFQ92465.1 - 0.015 15.2 0.3 1.9 8.4 0.1 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Longin PF13774.6 KFQ92466.1 - 1.8e-13 50.3 0.0 3e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Hexokinase_2 PF03727.16 KFQ92467.1 - 1.6e-81 273.3 0.1 2.2e-81 272.8 0.1 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KFQ92467.1 - 2.7e-58 197.1 0.3 3e-28 99.1 0.0 2.3 1 1 1 2 2 2 2 Hexokinase DNA_pol_E_B PF04042.16 KFQ92468.1 - 5.7e-40 136.9 0.5 2.1e-39 135.1 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KFQ92468.1 - 5.8e-28 97.6 0.1 4.3e-27 94.8 0.1 2.2 1 1 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Peptidase_M14 PF00246.24 KFQ92469.1 - 5.2e-70 236.5 0.0 6.7e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase F5_F8_type_C PF00754.25 KFQ92469.1 - 4.4e-17 62.4 0.1 1e-16 61.2 0.1 1.6 1 0 0 1 1 1 1 F5/8 type C domain CarboxypepD_reg PF13620.6 KFQ92469.1 - 6.4e-14 52.0 0.0 1.2e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KFQ92469.1 - 1e-05 25.4 0.1 2.5e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 CarboxypepD_reg-like domain Gelsolin PF00626.22 KFQ92470.1 - 8e-13 48.1 0.0 6.2e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 Gelsolin repeat Cofilin_ADF PF00241.20 KFQ92471.1 - 3.1e-14 52.8 0.0 4.3e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_9 PF14604.6 KFQ92471.1 - 1.7e-09 37.4 0.4 6.8e-09 35.4 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFQ92471.1 - 4.8e-07 29.3 0.1 1.6e-06 27.6 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFQ92471.1 - 0.00015 21.4 0.0 0.00039 20.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain HTH_37 PF13744.6 KFQ92471.1 - 0.025 14.5 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Peptidase_C14 PF00656.22 KFQ92472.1 - 1.9e-27 96.8 0.0 2.2e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Amino_oxidase PF01593.24 KFQ92473.1 - 0.00069 19.0 0.0 0.0069 15.7 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Mdv1 PF11542.8 KFQ92473.1 - 0.027 14.4 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial division protein 1 ELMO_CED12 PF04727.13 KFQ92474.1 - 1.2e-30 106.9 0.0 1.8e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family 7tm_1 PF00001.21 KFQ92475.1 - 1.1e-75 254.3 0.0 1.3e-75 254.1 0.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ92475.1 - 2.3e-15 56.7 1.9 1.9e-14 53.7 1.9 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFQ92475.1 - 3.4e-09 36.7 3.1 3.4e-09 36.7 3.1 1.7 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFQ92475.1 - 3.4e-08 33.6 1.6 3.7e-06 26.9 1.3 2.2 2 0 0 2 2 2 2 Olfactory receptor TMEM144 PF07857.12 KFQ92475.1 - 2.2 7.2 6.9 35 3.2 0.0 3.0 3 0 0 3 3 3 0 Transmembrane family, TMEM144 of transporters DUF5453 PF17534.2 KFQ92475.1 - 4.7 7.1 8.9 0.1 12.5 1.4 1.9 3 0 0 3 3 3 0 Family of unknown function (DUF5453) Acyltransferase PF01553.21 KFQ92476.1 - 2.4e-05 24.0 0.0 4.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase FAA_hydrolase PF01557.18 KFQ92477.1 - 1e-63 214.9 0.0 1.2e-63 214.7 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family zf-C2H2 PF00096.26 KFQ92478.1 - 4.5e-14 52.0 3.8 1.7e-06 28.2 0.2 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ92478.1 - 8e-13 48.2 7.1 8.3e-12 45.0 0.5 2.2 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ92478.1 - 2.6e-09 37.1 3.5 0.0002 21.9 0.4 2.0 2 0 0 2 2 2 2 C2H2-type zinc finger XPA_N PF01286.18 KFQ92478.1 - 4.9e-06 26.5 2.2 0.0056 16.7 0.0 2.1 2 0 0 2 2 2 2 XPA protein N-terminal zf-C2H2_jaz PF12171.8 KFQ92478.1 - 7.8e-06 26.0 0.2 0.099 13.0 0.0 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFQ92478.1 - 0.00017 21.5 4.4 0.041 13.9 0.5 2.3 2 1 0 2 2 2 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFQ92478.1 - 0.00082 19.4 7.0 0.0088 16.1 1.6 1.8 1 1 1 2 2 2 2 Zinc ribbon domain zf-BED PF02892.15 KFQ92478.1 - 0.00086 19.3 1.0 0.32 11.1 0.1 2.1 1 1 1 2 2 2 2 BED zinc finger HNH PF01844.23 KFQ92478.1 - 0.0013 18.9 1.1 0.64 10.2 0.1 2.0 2 0 0 2 2 2 2 HNH endonuclease zf-LYAR PF08790.11 KFQ92478.1 - 0.002 18.0 0.2 1.1 9.3 0.0 2.3 2 1 0 2 2 2 2 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 KFQ92478.1 - 0.0037 16.8 0.7 0.42 10.3 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 KFQ92478.1 - 0.009 16.4 0.3 3.1 8.3 0.1 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 KFQ92478.1 - 0.0094 15.6 0.3 2.3 7.9 0.0 2.0 1 1 1 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain FYVE PF01363.21 KFQ92478.1 - 0.015 15.4 0.5 0.022 14.9 0.5 1.4 1 1 0 1 1 1 0 FYVE zinc finger DZR PF12773.7 KFQ92478.1 - 0.018 15.1 0.5 0.023 14.7 0.5 1.2 1 0 0 1 1 1 0 Double zinc ribbon YhfH PF14149.6 KFQ92478.1 - 0.021 14.8 2.1 4.3 7.4 0.5 2.1 2 0 0 2 2 2 0 YhfH-like protein CpXC PF14353.6 KFQ92478.1 - 0.026 14.6 0.4 2.9 8.0 0.1 2.0 2 0 0 2 2 2 0 CpXC protein zf-C2H2_11 PF16622.5 KFQ92478.1 - 0.032 14.0 4.2 1.2 9.0 0.7 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type C1_1 PF00130.22 KFQ92478.1 - 0.052 13.4 0.5 2.6 8.0 0.5 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf_C2HC_14 PF18574.1 KFQ92478.1 - 0.055 13.3 5.0 5.3 6.9 0.1 3.0 2 1 0 2 2 2 0 C2HC Zing finger domain zf-C2H2_2 PF12756.7 KFQ92478.1 - 0.059 13.7 0.3 0.89 9.9 0.0 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) CxC7 PF18866.1 KFQ92478.1 - 0.1 12.7 1.3 5.7 7.2 0.1 2.1 1 1 1 2 2 2 0 CxC7 like cysteine cluster associated with KDZ transposases TFIIS_C PF01096.18 KFQ92478.1 - 0.11 12.4 3.4 2.3 8.1 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn_ribbon_recom PF13408.6 KFQ92478.1 - 0.19 12.3 2.7 5.8 7.5 1.1 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain RNA_POL_M_15KD PF02150.16 KFQ92478.1 - 0.19 11.6 2.4 0.2 11.6 0.1 1.9 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit DUF326 PF03860.16 KFQ92478.1 - 7.9 6.6 8.0 4.1 7.5 1.7 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF326) SRCR PF00530.18 KFQ92479.1 - 1.2e-129 423.6 43.0 1.1e-32 112.5 3.9 4.1 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFQ92479.1 - 6.8e-19 68.2 15.8 0.00035 21.0 0.3 4.3 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFQ92479.1 - 1.3e-06 28.9 5.5 1.4 9.5 0.1 4.4 4 0 0 4 4 4 4 Hepsin, SRCR domain PEP-utilizers PF00391.23 KFQ92479.1 - 0.0053 16.4 0.0 4.9 7.0 0.0 3.5 4 0 0 4 4 4 1 PEP-utilising enzyme, mobile domain ENOD93 PF03386.14 KFQ92479.1 - 0.15 12.0 0.0 9.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Early nodulin 93 ENOD93 protein SRCR PF00530.18 KFQ92480.1 - 5.6e-125 408.7 45.1 4e-33 113.9 6.0 4.1 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFQ92480.1 - 2.3e-21 76.1 18.4 8.5e-05 23.0 0.5 4.6 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFQ92480.1 - 6.2e-08 33.1 6.6 0.59 10.7 0.1 4.5 4 0 0 4 4 4 4 Hepsin, SRCR domain tRNA_Me_trans PF03054.16 KFQ92480.1 - 0.17 10.6 3.2 13 4.4 0.1 3.6 4 0 0 4 4 4 0 tRNA methyl transferase DUF3027 PF11228.8 KFQ92480.1 - 4.2 7.3 22.1 5.4 7.0 0.5 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3027) zf-H2C2_2 PF13465.6 KFQ92481.1 - 1.9e-42 141.9 44.9 1.5e-08 34.7 0.9 7.0 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ92481.1 - 3.4e-36 121.7 40.5 1.6e-06 28.2 0.6 7.1 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ92481.1 - 1.1e-22 78.8 43.0 0.00017 22.2 0.2 7.1 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ92481.1 - 4.9e-17 61.7 18.8 0.0032 17.7 0.0 7.2 6 1 1 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFQ92481.1 - 2e-13 50.2 29.2 0.0007 19.9 0.4 6.3 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFQ92481.1 - 2.3e-07 30.7 40.7 0.29 11.2 0.2 7.3 7 0 0 7 7 7 5 C2H2-type zinc finger XPA_N PF01286.18 KFQ92481.1 - 1.4e-05 25.1 13.7 0.94 9.6 0.1 6.1 6 0 0 6 6 6 1 XPA protein N-terminal zf-Di19 PF05605.12 KFQ92481.1 - 4.2e-05 23.8 27.6 0.04 14.2 0.9 4.3 2 1 3 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding DUF3268 PF11672.8 KFQ92481.1 - 7.1e-05 23.1 9.5 0.18 12.1 0.1 3.1 3 0 0 3 3 3 2 zinc-finger-containing domain zf_UBZ PF18439.1 KFQ92481.1 - 8.5e-05 22.1 15.4 3.1 7.5 0.0 6.1 6 0 0 6 6 6 1 Ubiquitin-Binding Zinc Finger Prok-RING_1 PF14446.6 KFQ92481.1 - 0.00011 22.0 13.0 13 5.8 0.0 6.1 5 1 1 6 6 6 0 Prokaryotic RING finger family 1 PHF5 PF03660.14 KFQ92481.1 - 0.00086 19.5 7.7 1.2 9.4 0.2 3.1 1 1 2 3 3 3 1 PHF5-like protein BolA PF01722.18 KFQ92481.1 - 0.0012 19.0 2.1 2 8.7 0.4 3.0 1 1 0 2 2 2 2 BolA-like protein Zn_ribbon_SprT PF17283.2 KFQ92481.1 - 0.0013 18.5 16.4 0.094 12.6 0.2 4.3 3 1 1 4 4 4 1 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 KFQ92481.1 - 0.0016 18.5 21.2 0.15 12.2 2.0 4.9 1 1 6 7 7 7 3 Zinc ribbon domain FYDLN_acid PF09538.10 KFQ92481.1 - 0.0053 17.4 7.4 2.9 8.6 0.2 4.7 1 1 3 4 4 4 1 Protein of unknown function (FYDLN_acid) zf-trcl PF13451.6 KFQ92481.1 - 0.011 15.7 16.2 1.5 8.8 0.1 5.7 6 0 0 6 6 6 0 Probable zinc-ribbon domain Zf_RING PF16744.5 KFQ92481.1 - 0.012 15.7 16.1 2 8.6 0.1 5.5 1 1 4 5 5 5 0 KIAA1045 RING finger LIM PF00412.22 KFQ92481.1 - 0.036 14.3 18.6 0.31 11.3 1.2 5.0 1 1 1 4 4 4 0 LIM domain zf-AN1 PF01428.16 KFQ92481.1 - 0.046 13.9 25.9 9.1 6.5 0.1 6.2 5 1 1 6 6 6 0 AN1-like Zinc finger zinc-ribbons_6 PF07191.12 KFQ92481.1 - 0.12 12.3 18.2 3.2 7.8 1.2 5.2 2 2 4 6 6 6 0 zinc-ribbons zinc_ribbon_15 PF17032.5 KFQ92481.1 - 0.18 12.6 12.6 6.1 7.7 3.1 3.5 1 1 1 3 3 3 0 zinc-ribbon family zf-C2HC_2 PF13913.6 KFQ92481.1 - 0.23 11.4 29.7 0.44 10.5 0.1 6.9 6 2 0 6 6 6 0 zinc-finger of a C2HC-type CpXC PF14353.6 KFQ92481.1 - 0.37 10.8 13.6 10 6.2 0.1 5.1 2 2 2 5 5 5 0 CpXC protein HypA PF01155.19 KFQ92481.1 - 0.44 10.6 12.5 1.2 9.2 0.8 3.3 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_C2H2_ZHX PF18387.1 KFQ92481.1 - 0.56 9.9 0.0 0.56 9.9 0.0 4.6 1 1 4 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF2225 PF09986.9 KFQ92481.1 - 0.66 9.7 12.0 3.7 7.2 0.3 4.3 3 2 2 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2225) zinc_ribbon_9 PF14369.6 KFQ92481.1 - 0.7 10.2 0.1 0.7 10.2 0.1 5.3 6 0 0 6 6 6 0 zinc-ribbon Chordopox_RPO7 PF05864.12 KFQ92481.1 - 0.79 10.0 5.5 2.5 8.4 0.0 3.8 5 1 0 5 5 4 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Ribosomal_L28 PF00830.19 KFQ92481.1 - 0.97 9.7 13.6 1.2 9.4 0.3 4.5 5 1 0 5 5 4 0 Ribosomal L28 family DUF2256 PF10013.9 KFQ92481.1 - 1.5 9.0 20.4 10 6.3 0.2 5.9 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-HIT PF04438.16 KFQ92481.1 - 2.3 8.2 26.8 1.4 8.9 0.6 5.8 6 0 0 6 6 6 0 HIT zinc finger FYVE PF01363.21 KFQ92481.1 - 2.8 8.2 23.7 39 4.5 11.4 4.1 1 1 2 3 3 3 0 FYVE zinc finger Zn_ribbon_recom PF13408.6 KFQ92481.1 - 3.1 8.4 18.8 19 5.9 2.2 4.3 1 1 3 4 4 4 0 Recombinase zinc beta ribbon domain Rad50_zn_hook PF04423.14 KFQ92481.1 - 3.7 7.5 6.8 6.1 6.8 0.0 3.2 4 0 0 4 4 3 0 Rad50 zinc hook motif zf-MYST PF17772.1 KFQ92481.1 - 3.7 7.2 17.1 15 5.3 2.1 5.2 2 2 4 6 6 6 0 MYST family zinc finger domain DUF2180 PF09947.9 KFQ92481.1 - 6.6 6.8 15.4 6.6e+02 0.4 11.6 3.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) Cript PF10235.9 KFQ92481.1 - 7.7 7.2 20.2 2.8 8.6 0.2 4.6 2 1 3 5 5 5 0 Microtubule-associated protein CRIPT SRCR PF00530.18 KFQ92482.1 - 1.1e-33 115.7 4.9 1.3e-33 115.5 4.9 1.0 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFQ92482.1 - 1.6e-05 25.3 0.4 3e-05 24.5 0.4 1.4 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR PF00530.18 KFQ92483.1 - 5.6e-132 431.1 47.5 3.1e-33 114.3 4.0 4.1 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFQ92483.1 - 1.6e-17 63.9 19.7 0.00021 21.8 0.5 4.4 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFQ92483.1 - 8e-07 29.6 7.0 0.29 11.6 0.1 4.4 4 0 0 4 4 4 4 Hepsin, SRCR domain TYW3 PF02676.14 KFQ92483.1 - 0.39 10.0 9.2 2.5 7.4 0.1 3.6 4 0 0 4 4 4 0 Methyltransferase TYW3 FIIND PF13553.6 KFQ92485.1 - 0.013 14.9 0.2 0.015 14.8 0.2 1.0 1 0 0 1 1 1 0 Function to find PRY PF13765.6 KFQ92485.1 - 0.04 13.5 0.0 0.082 12.6 0.0 1.6 1 1 1 2 2 2 0 SPRY-associated domain DUF3088 PF11287.8 KFQ92485.1 - 0.095 12.5 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3088) Tetraspanin PF00335.20 KFQ92486.1 - 1.6e-23 83.6 3.0 1.8e-23 83.5 3.0 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF1899 PF08953.11 KFQ92487.1 - 9.5e-30 102.3 0.2 1.6e-29 101.5 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KFQ92487.1 - 2.5e-20 72.1 0.0 4e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KFQ92487.1 - 4.1e-19 68.6 3.0 4.6e-06 27.3 0.2 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ92487.1 - 2e-09 37.6 0.0 3.3e-05 24.1 0.0 3.4 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Sacchrp_dh_NADP PF03435.18 KFQ92487.1 - 0.013 15.8 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain SGL PF08450.12 KFQ92487.1 - 0.033 13.8 0.0 0.082 12.5 0.0 1.4 1 1 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Calpain_III PF01067.22 KFQ92487.1 - 0.13 12.6 0.1 0.29 11.4 0.1 1.6 1 0 0 1 1 1 0 Calpain large subunit, domain III Ge1_WD40 PF16529.5 KFQ92487.1 - 0.13 11.2 0.1 1.5 7.7 0.0 2.2 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF249 PF03158.13 KFQ92487.1 - 0.15 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Multigene family 530 protein RabGAP-TBC PF00566.18 KFQ92488.1 - 2e-53 181.2 1.1 2e-53 181.2 1.1 2.4 3 1 0 3 3 3 1 Rab-GTPase-TBC domain PH PF00169.29 KFQ92488.1 - 3.1e-12 46.9 0.1 8.4e-12 45.5 0.1 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFQ92488.1 - 0.00017 21.8 0.1 0.0005 20.3 0.1 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 KFQ92488.1 - 0.0024 18.3 0.8 0.034 14.6 0.8 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain Vps23_core PF09454.10 KFQ92488.1 - 0.1 12.6 1.5 0.26 11.2 0.3 2.4 2 0 0 2 2 2 0 Vps23 core domain BPS PF08947.10 KFQ92488.1 - 0.27 11.1 2.2 0.72 9.7 2.2 1.7 1 0 0 1 1 1 0 BPS (Between PH and SH2) VIT1 PF01988.19 KFQ92488.1 - 0.56 10.0 2.7 1.3 8.8 2.7 1.6 1 0 0 1 1 1 0 VIT family Spc29 PF17082.5 KFQ92488.1 - 0.74 9.6 13.5 2.6 7.8 0.8 2.6 1 1 1 2 2 2 0 Spindle Pole Component 29 FAD_SOX PF18371.1 KFQ92488.1 - 2 8.8 6.6 0.5 10.8 1.4 2.7 3 0 0 3 3 3 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase NPV_P10 PF05531.12 KFQ92488.1 - 9.6 6.8 14.4 3.5 8.1 1.5 3.9 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Actin PF00022.19 KFQ92489.1 - 1.5e-101 340.0 0.0 1.1e-99 333.9 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KFQ92489.1 - 0.0012 17.7 0.2 0.024 13.4 0.2 2.4 1 1 0 1 1 1 1 MreB/Mbl protein DnaJ_C PF01556.18 KFQ92490.1 - 1.9e-44 151.3 0.4 2.6e-44 150.9 0.4 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KFQ92490.1 - 4.7e-15 55.7 20.7 8.3e-15 54.9 20.7 1.4 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.31 KFQ92490.1 - 5.6e-06 26.4 0.2 1.1e-05 25.5 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain Anti-TRAP PF15777.5 KFQ92490.1 - 0.032 14.2 11.8 0.44 10.5 4.5 2.6 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KFQ92490.1 - 0.054 13.5 7.8 0.66 10.0 0.7 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA WD40 PF00400.32 KFQ92491.1 - 1.2e-40 136.7 8.9 7.6e-08 32.9 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ92491.1 - 5.5e-18 65.1 0.2 1.2e-05 25.5 0.0 5.5 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 KFQ92491.1 - 1.2e-13 50.4 0.2 2.3e-13 49.5 0.2 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 KFQ92491.1 - 1.3e-13 50.6 0.6 0.0025 16.8 0.1 3.6 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFQ92491.1 - 4.2e-09 35.6 0.3 0.00087 18.1 0.1 3.9 2 1 2 4 4 4 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KFQ92491.1 - 0.0015 18.4 1.3 1.2 8.9 0.2 3.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Hira PF07569.11 KFQ92491.1 - 0.0033 17.2 1.7 1.6 8.4 0.0 4.4 5 0 0 5 5 5 1 TUP1-like enhancer of split PD40 PF07676.12 KFQ92491.1 - 0.018 14.9 0.0 0.7 9.9 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat LisH PF08513.11 KFQ92491.1 - 0.022 14.7 0.0 0.051 13.6 0.0 1.7 1 0 0 1 1 1 0 LisH Glyco_transf_7N PF13733.6 KFQ92492.1 - 3e-58 195.2 0.1 4.1e-58 194.8 0.1 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 KFQ92492.1 - 6.3e-27 93.1 0.8 1.2e-26 92.1 0.8 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Kazal_1 PF00050.21 KFQ92493.1 - 3.5e-17 62.2 5.2 9.2e-16 57.6 5.2 2.0 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KFQ92493.1 - 5.4e-12 45.6 4.4 5.5e-12 45.6 0.7 2.0 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain zf-RING_11 PF17123.5 KFQ92493.1 - 0.18 11.6 0.7 0.18 11.6 0.7 2.0 2 0 0 2 2 2 0 RING-like zinc finger XPA_C PF05181.12 KFQ92494.1 - 9.7e-30 102.3 0.7 1.1e-29 102.2 0.7 1.0 1 0 0 1 1 1 1 XPA protein C-terminus MIF4G_like_2 PF09090.11 KFQ92495.1 - 5.5e-86 288.3 3.1 1.3e-85 287.1 3.1 1.6 1 0 0 1 1 1 1 MIF4G like MIF4G_like PF09088.11 KFQ92495.1 - 9e-37 126.7 0.9 5.7e-36 124.1 0.6 2.3 2 0 0 2 2 2 1 MIF4G like MIF4G PF02854.19 KFQ92495.1 - 1.4e-26 93.4 0.1 1.4e-26 93.4 0.1 2.5 3 0 0 3 3 3 1 MIF4G domain DUF4611 PF15387.6 KFQ92495.1 - 0.035 14.3 1.0 0.035 14.3 1.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Vfa1 PF08432.10 KFQ92495.1 - 0.072 13.4 1.2 0.14 12.4 1.2 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nuf2 PF03800.14 KFQ92495.1 - 0.073 13.2 0.0 3.8 7.6 0.0 2.7 1 1 1 2 2 2 0 Nuf2 family Mis12 PF05859.12 KFQ92495.1 - 0.1 12.6 2.0 0.37 10.8 1.4 2.3 2 0 0 2 2 2 0 Mis12 protein ApoA-II PF04711.13 KFQ92495.1 - 0.15 12.2 0.8 0.64 10.2 0.0 2.4 3 0 0 3 3 3 0 Apolipoprotein A-II (ApoA-II) DASH_Spc34 PF08657.10 KFQ92495.1 - 0.41 10.4 5.7 0.78 9.5 5.7 1.4 1 0 0 1 1 1 0 DASH complex subunit Spc34 PBP1_TM PF14812.6 KFQ92495.1 - 0.91 9.9 10.9 0.11 12.9 5.6 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UPF0176_N PF17773.1 KFQ92496.1 - 1.4e-17 63.9 0.0 2.3e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 KFQ92496.1 - 7.9e-16 58.2 11.5 7.9e-16 58.2 11.5 2.2 2 0 0 2 2 2 1 Rhodanase C-terminal Rhodanese PF00581.20 KFQ92496.1 - 3e-07 30.9 0.1 9e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain NRDD PF13597.6 KFQ92496.1 - 0.064 12.0 1.5 0.1 11.3 1.5 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase Tropomodulin PF03250.14 KFQ92497.1 - 4.5e-45 153.2 0.5 4.5e-45 153.2 0.5 1.7 2 0 0 2 2 2 1 Tropomodulin LRR_6 PF13516.6 KFQ92497.1 - 0.041 13.9 0.1 0.17 12.0 0.1 2.2 1 0 0 1 1 1 0 Leucine Rich repeat DUF3644 PF12358.8 KFQ92497.1 - 0.066 13.7 0.3 0.32 11.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3644) TUDOR PF00567.24 KFQ92498.1 - 3.8e-64 214.2 0.6 1.4e-25 89.7 0.0 3.4 3 0 0 3 3 3 3 Tudor domain Amelin PF05111.12 KFQ92498.1 - 0.091 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Ameloblastin precursor (Amelin) zf-CpG_bind_C PF12269.8 KFQ92500.1 - 1.2e-30 107.1 0.2 1.3e-30 106.9 0.2 1.0 1 0 0 1 1 1 1 CpG binding protein zinc finger C terminal domain CD34_antigen PF06365.12 KFQ92501.1 - 2.3e-81 272.4 0.0 3.2e-81 271.9 0.0 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family Shisa PF13908.6 KFQ92501.1 - 0.077 13.2 1.5 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator PMP1_2 PF08114.11 KFQ92501.1 - 0.23 11.2 2.8 0.44 10.3 2.8 1.4 1 0 0 1 1 1 0 ATPase proteolipid family BTB PF00651.31 KFQ92502.1 - 1.2e-43 147.8 2.7 1.2e-20 73.7 0.1 3.4 2 1 1 3 3 3 3 BTB/POZ domain Ank_2 PF12796.7 KFQ92502.1 - 2e-07 31.5 0.0 1.8e-06 28.4 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFQ92502.1 - 2.1e-07 31.1 0.1 6.4e-07 29.5 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFQ92502.1 - 1.7e-06 28.4 0.2 1.2e-05 25.8 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF3342 PF11822.8 KFQ92502.1 - 1.5e-05 25.1 0.6 0.022 15.0 0.1 3.6 2 1 1 3 3 3 1 Domain of unknown function (DUF3342) Ank_3 PF13606.6 KFQ92502.1 - 5.2e-05 23.3 0.4 0.00084 19.6 0.0 3.2 4 0 0 4 4 3 1 Ankyrin repeat BACK PF07707.15 KFQ92502.1 - 0.0011 19.1 0.2 0.0035 17.4 0.2 1.9 1 0 0 1 1 1 1 BTB And C-terminal Kelch Ank PF00023.30 KFQ92502.1 - 0.0012 19.1 0.0 0.0041 17.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat P4Ha_N PF08336.11 KFQ92502.1 - 0.031 14.3 1.6 0.091 12.8 0.3 2.3 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Orn_Arg_deC_N PF02784.16 KFQ92502.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain IFT20 PF14931.6 KFQ92502.1 - 0.47 10.6 4.7 0.4 10.8 2.5 2.0 2 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 BACK PF07707.15 KFQ92503.1 - 9.2e-29 99.6 1.7 9.2e-29 99.6 1.7 2.6 3 0 0 3 3 3 1 BTB And C-terminal Kelch Kelch_1 PF01344.25 KFQ92503.1 - 1.2e-28 98.4 10.1 1.8e-09 37.0 0.0 5.1 5 1 0 5 5 5 4 Kelch motif BTB PF00651.31 KFQ92503.1 - 9.7e-23 80.5 1.9 9.7e-23 80.5 1.9 1.9 2 0 0 2 2 2 1 BTB/POZ domain Kelch_6 PF13964.6 KFQ92503.1 - 1.2e-21 76.2 4.0 3.3e-08 33.5 0.0 5.1 4 1 1 5 5 5 3 Kelch motif Kelch_2 PF07646.15 KFQ92503.1 - 5.7e-15 54.6 3.6 2.4e-07 30.5 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 KFQ92503.1 - 4.8e-10 39.2 0.4 0.00015 21.7 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 KFQ92503.1 - 5.4e-10 39.3 2.2 0.003 17.8 0.0 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_4 PF13418.6 KFQ92503.1 - 8e-10 38.6 6.1 0.001 19.0 0.0 5.1 5 1 0 5 5 5 3 Galactose oxidase, central domain DUF3342 PF11822.8 KFQ92503.1 - 0.00017 21.7 1.8 0.00085 19.5 0.2 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3342) UFD1 PF03152.14 KFQ92503.1 - 0.13 11.7 0.2 0.27 10.7 0.2 1.5 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 SecY PF00344.20 KFQ92504.1 - 7.1e-77 258.7 12.0 9.5e-77 258.3 12.0 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KFQ92504.1 - 8.2e-19 67.2 0.2 2.4e-18 65.7 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p YlaH PF14036.6 KFQ92504.1 - 0.11 12.8 3.3 1.9 8.8 0.2 3.2 3 0 0 3 3 3 0 YlaH-like protein DUF2975 PF11188.8 KFQ92504.1 - 0.25 11.2 9.1 0.065 13.1 0.7 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF2975) TIP49 PF06068.13 KFQ92505.1 - 5.1e-173 575.2 0.2 6.3e-173 574.9 0.2 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KFQ92505.1 - 2.5e-27 94.8 0.1 6.8e-27 93.4 0.1 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KFQ92505.1 - 5.4e-13 49.5 0.3 2.8e-08 34.2 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFQ92505.1 - 1.2e-11 44.6 0.1 3.4e-08 33.4 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFQ92505.1 - 3.3e-06 27.4 0.1 0.12 12.7 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KFQ92505.1 - 3.7e-05 24.2 0.0 0.00031 21.2 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KFQ92505.1 - 5.4e-05 23.2 0.1 0.0041 17.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KFQ92505.1 - 0.00016 21.3 0.0 0.00086 18.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KFQ92505.1 - 0.00018 21.3 0.1 0.2 11.3 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 KFQ92505.1 - 0.00073 19.0 0.2 0.037 13.4 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KFQ92505.1 - 0.001 19.4 1.5 0.029 14.7 1.5 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFQ92505.1 - 0.0015 19.1 0.0 0.011 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KFQ92505.1 - 0.0021 17.8 0.0 0.0045 16.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 KFQ92505.1 - 0.0025 18.1 0.1 0.0047 17.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KFQ92505.1 - 0.0031 16.9 0.0 0.0065 15.8 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain ResIII PF04851.15 KFQ92505.1 - 0.0089 16.0 0.0 0.35 10.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 KFQ92505.1 - 0.011 15.0 0.2 0.032 13.5 0.1 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 KFQ92505.1 - 0.011 15.9 0.0 0.031 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KFQ92505.1 - 0.011 15.2 0.1 0.035 13.6 0.1 1.8 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 KFQ92505.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 KFQ92505.1 - 0.015 15.3 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KFQ92505.1 - 0.017 14.7 0.1 0.062 12.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 KFQ92505.1 - 0.017 14.2 0.0 0.039 13.0 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 KFQ92505.1 - 0.02 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFQ92505.1 - 0.038 13.7 0.2 0.81 9.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KFQ92505.1 - 0.046 13.1 1.3 0.2 11.0 0.0 2.5 3 0 0 3 3 3 0 KaiC AAA_14 PF13173.6 KFQ92505.1 - 0.059 13.4 0.0 8.6 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KFQ92505.1 - 0.073 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DNA_pol3_delta2 PF13177.6 KFQ92505.1 - 0.074 12.8 0.0 1.9 8.3 0.0 2.2 2 1 0 2 2 2 0 DNA polymerase III, delta subunit AAA_lid_4 PF17864.1 KFQ92505.1 - 0.081 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 RuvB AAA lid domain RNA_helicase PF00910.22 KFQ92505.1 - 0.1 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase GTP_EFTU_D2 PF03144.25 KFQ92506.1 - 5e-08 33.2 0.1 1.3e-07 31.9 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU PF00009.27 KFQ92506.1 - 6.5e-08 32.3 0.0 9.7e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.19 KFQ92506.1 - 0.00017 21.2 1.0 0.00027 20.6 1.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain FliS_cochap PF16522.5 KFQ92506.1 - 0.0083 16.1 0.9 0.039 13.9 0.3 2.3 3 0 0 3 3 3 1 Flagellar FLiS export co-chaperone, HP1076 Gtr1_RagA PF04670.12 KFQ92506.1 - 0.096 12.0 0.1 0.23 10.8 0.1 1.6 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KFQ92506.1 - 0.11 12.4 0.2 0.35 10.8 0.1 1.9 2 0 0 2 2 2 0 RsgA GTPase Ribophorin_I PF04597.14 KFQ92507.1 - 6.6e-137 457.3 8.0 8.3e-137 457.0 8.0 1.1 1 0 0 1 1 1 1 Ribophorin I DNA_repr_REX1B PF14966.6 KFQ92507.1 - 0.0013 19.4 0.9 0.0027 18.3 0.4 1.8 2 0 0 2 2 2 1 DNA repair REX1-B Ras PF00071.22 KFQ92508.1 - 1.6e-58 196.9 0.1 1.9e-58 196.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ92508.1 - 2.3e-32 111.7 0.0 3.8e-32 111.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ92508.1 - 2.5e-13 49.9 0.1 3e-13 49.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFQ92508.1 - 2.4e-07 30.8 0.0 4.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFQ92508.1 - 2.6e-06 27.5 0.2 0.0033 17.3 0.1 2.2 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KFQ92508.1 - 3.5e-06 26.5 0.0 4.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFQ92508.1 - 1.2e-05 25.0 0.0 0.00077 19.0 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.19 KFQ92508.1 - 0.0026 17.4 0.0 0.0096 15.5 0.0 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 KFQ92508.1 - 0.0028 17.0 0.6 0.021 14.1 0.1 2.1 2 1 0 2 2 2 1 Septin ATP_bind_1 PF03029.17 KFQ92508.1 - 0.0031 17.3 0.3 0.084 12.6 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KFQ92508.1 - 0.0051 17.1 0.0 0.014 15.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 KFQ92508.1 - 0.0053 16.5 0.0 0.12 12.1 0.1 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KFQ92508.1 - 0.012 15.2 0.1 0.019 14.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KFQ92508.1 - 0.015 15.0 0.1 0.027 14.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 KFQ92508.1 - 0.016 14.7 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KFQ92508.1 - 0.019 15.3 0.1 0.036 14.4 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 KFQ92508.1 - 0.023 14.6 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.14 KFQ92508.1 - 0.025 14.6 0.0 0.041 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 KFQ92508.1 - 0.04 13.1 1.2 0.3 10.2 0.2 2.2 2 1 1 3 3 3 0 G-protein alpha subunit TniB PF05621.11 KFQ92508.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein ATPase_2 PF01637.18 KFQ92508.1 - 0.07 13.0 0.7 0.11 12.3 0.1 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KFQ92508.1 - 0.087 12.0 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 KFQ92508.1 - 0.089 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KFQ92508.1 - 0.18 12.4 0.1 0.5 10.9 0.0 1.7 2 0 0 2 2 2 0 ABC transporter Linker_histone PF00538.19 KFQ92509.1 - 1.1e-18 67.3 0.2 1.1e-18 67.3 0.2 1.6 2 0 0 2 2 2 1 linker histone H1 and H5 family DUF2572 PF10833.8 KFQ92509.1 - 0.063 13.0 0.7 0.083 12.6 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) Histone_H2A_C PF16211.5 KFQ92510.1 - 8.1e-21 73.5 1.2 1.4e-20 72.7 1.2 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFQ92510.1 - 6e-17 62.2 0.0 7.3e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFQ92510.1 - 5.7e-05 23.3 0.0 7.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SRAP PF02586.14 KFQ92511.1 - 1.3e-49 168.7 0.0 2.5e-49 167.8 0.0 1.5 2 0 0 2 2 2 1 SOS response associated peptidase (SRAP) Adaptin_N PF01602.20 KFQ92512.1 - 6.1e-136 454.0 10.3 7.7e-136 453.7 10.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KFQ92512.1 - 3.7e-59 199.2 0.7 8.5e-59 198.0 0.7 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KFQ92512.1 - 4.7e-38 129.8 0.0 1e-37 128.7 0.0 1.6 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KFQ92512.1 - 5.3e-18 65.2 0.1 3.9e-08 33.6 0.0 6.2 3 2 3 7 7 7 3 HEAT repeats Cnd1 PF12717.7 KFQ92512.1 - 2.7e-13 50.3 10.8 0.0013 18.8 0.1 5.4 4 1 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFQ92512.1 - 1.2e-05 25.1 4.3 9 6.9 0.0 7.0 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.6 KFQ92512.1 - 4.5e-05 23.9 0.7 0.51 10.9 0.1 3.9 4 0 0 4 4 3 2 HEAT-like repeat MOR2-PAG1_C PF14225.6 KFQ92512.1 - 0.052 13.4 0.2 0.13 12.1 0.2 1.7 1 0 0 1 1 1 0 Cell morphogenesis C-terminal HEAT_PBS PF03130.16 KFQ92512.1 - 0.071 13.8 1.3 29 5.7 0.0 4.6 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Arm PF00514.23 KFQ92512.1 - 0.088 12.9 0.1 6.8 6.9 0.0 4.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 KFQ92512.1 - 0.27 11.2 2.5 0.45 10.5 0.2 2.6 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central Peptidase_M16 PF00675.20 KFQ92513.1 - 5.6e-50 169.2 0.1 8.7e-50 168.6 0.1 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFQ92513.1 - 4.1e-37 128.0 0.0 4.3e-36 124.7 0.0 2.2 2 1 0 2 2 2 1 Peptidase M16 inactive domain PvlArgDC PF01862.16 KFQ92513.1 - 0.044 13.6 0.1 0.081 12.7 0.1 1.4 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) SAP30_Sin3_bdg PF13867.6 KFQ92513.1 - 0.078 13.3 0.0 18 5.7 0.0 2.5 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Virulence_RhuM PF13310.6 KFQ92513.1 - 0.097 11.9 0.0 7 5.8 0.0 2.2 2 0 0 2 2 2 0 Virulence protein RhuM family DUF2013 PF09431.10 KFQ92514.1 - 5.2e-34 117.4 0.3 1.2e-33 116.2 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Rcd1 PF04078.13 KFQ92514.1 - 0.045 13.0 1.8 1.1 8.5 0.0 3.0 2 1 1 3 3 3 0 Cell differentiation family, Rcd1-like DUF1646 PF07854.12 KFQ92514.1 - 0.081 12.3 0.0 0.55 9.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1646) IPK PF03770.16 KFQ92515.1 - 1.1e-64 217.9 0.3 1.1e-64 217.9 0.3 1.6 1 1 0 1 1 1 1 Inositol polyphosphate kinase SpoU_sub_bind PF08032.12 KFQ92515.1 - 0.096 13.0 0.4 0.26 11.6 0.4 1.8 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding Abhydrolase_1 PF00561.20 KFQ92516.1 - 2.5e-24 86.3 0.0 9.3e-17 61.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFQ92516.1 - 4.1e-19 70.1 0.0 6.7e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFQ92516.1 - 8.3e-14 51.4 0.0 1.9e-12 47.0 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KFQ92516.1 - 2.7e-05 23.0 0.0 0.00024 19.9 0.0 2.0 1 1 0 1 1 1 1 Ndr family DUF1057 PF06342.12 KFQ92516.1 - 0.00099 18.2 0.0 0.0013 17.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) UPF0227 PF05728.12 KFQ92516.1 - 0.0044 17.0 0.2 2.3 8.1 0.0 2.4 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0227) Thioesterase PF00975.20 KFQ92516.1 - 0.0097 16.0 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain FSH1 PF03959.13 KFQ92516.1 - 0.03 14.0 0.2 1.9 8.1 0.0 2.5 2 1 1 3 3 3 0 Serine hydrolase (FSH1) Palm_thioest PF02089.15 KFQ92516.1 - 0.031 14.1 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Lipase PF00151.19 KFQ92516.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipase Exo_endo_phos PF03372.23 KFQ92517.1 - 1.2e-13 51.2 0.0 1.4e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Filamin PF00630.19 KFQ92518.1 - 0 1260.6 51.3 5e-20 72.2 0.0 24.1 24 0 0 24 24 24 24 Filamin/ABP280 repeat CH PF00307.31 KFQ92518.1 - 1e-17 64.3 0.0 1.8e-14 53.8 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain Y_Y_Y PF07495.13 KFQ92518.1 - 4.6e-16 58.5 26.7 0.42 10.6 0.0 14.5 17 0 0 17 17 15 5 Y_Y_Y domain Big_3_5 PF16640.5 KFQ92518.1 - 2.4e-15 56.5 31.5 0.13 12.5 1.8 14.2 16 0 0 16 16 16 5 Bacterial Ig-like domain (group 3) Invasin_D3 PF09134.10 KFQ92518.1 - 1.7e-13 50.7 23.7 0.027 14.8 0.0 11.0 13 1 0 13 13 12 4 Invasin, domain 3 DUF5060 PF16586.5 KFQ92518.1 - 5.9e-12 45.8 2.6 2.2 8.7 0.0 11.6 15 0 0 15 15 15 3 Domain of unknown function (DUF5060) YtkA PF13115.6 KFQ92518.1 - 9.8e-11 42.1 11.1 1.9 9.1 0.1 12.5 14 0 0 14 14 14 3 YtkA-like DUF2141 PF09912.9 KFQ92518.1 - 3.9e-05 23.5 0.8 33 4.4 0.0 7.0 7 0 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2141) BatD PF13584.6 KFQ92518.1 - 0.00013 20.9 0.5 0.23 10.2 0.0 3.3 4 0 0 4 4 4 2 Oxygen tolerance EMP24_GP25L PF01105.24 KFQ92518.1 - 0.00019 21.4 0.4 60 3.5 0.0 7.6 9 1 1 10 10 10 0 emp24/gp25L/p24 family/GOLD PapC_N PF13954.6 KFQ92518.1 - 0.0076 16.3 0.0 5.4 7.0 0.0 5.3 6 0 0 6 6 6 1 PapC N-terminal domain Big_1 PF02369.16 KFQ92518.1 - 0.034 14.1 7.6 60 3.7 0.1 8.1 9 0 0 9 9 9 0 Bacterial Ig-like domain (group 1) PEGA PF08308.11 KFQ92518.1 - 0.067 13.1 3.7 2.3e+02 1.8 0.2 7.4 6 0 0 6 6 6 0 PEGA domain FHA PF00498.26 KFQ92519.1 - 1.1e-17 64.1 0.1 2.9e-17 62.8 0.0 1.8 2 0 0 2 2 2 1 FHA domain GAS PF13851.6 KFQ92519.1 - 0.0019 17.6 120.9 0.026 13.9 11.1 6.8 3 2 3 6 6 6 4 Growth-arrest specific micro-tubule binding Lectin_N PF03954.14 KFQ92519.1 - 0.0091 15.7 5.7 0.0091 15.7 5.7 6.5 2 2 3 6 6 6 2 Hepatic lectin, N-terminal domain T3SSipB PF16535.5 KFQ92519.1 - 0.012 16.1 7.8 0.012 16.1 7.8 6.1 2 2 4 6 6 6 0 Type III cell invasion protein SipB DUF4472 PF14739.6 KFQ92519.1 - 0.017 15.9 14.7 0.017 15.9 14.7 8.2 2 2 6 8 8 8 0 Domain of unknown function (DUF4472) WD40_alt PF14077.6 KFQ92519.1 - 0.074 12.9 1.1 2 8.4 0.7 3.5 2 0 0 2 2 2 0 Alternative WD40 repeat motif DUF3138 PF11336.8 KFQ92519.1 - 0.66 8.5 4.1 0.25 9.9 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF812 PF05667.11 KFQ92519.1 - 9.1 5.0 107.8 0.099 11.5 26.1 4.6 2 1 3 5 5 5 0 Protein of unknown function (DUF812) SPA PF08616.10 KFQ92520.1 - 3.9e-16 59.0 0.2 4.9e-15 55.5 0.0 2.4 2 0 0 2 2 2 1 Stabilization of polarity axis DENN PF02141.21 KFQ92520.1 - 9.8e-06 25.6 3.6 9.8e-06 25.6 3.6 2.3 2 1 0 2 2 2 1 DENN (AEX-3) domain Avl9 PF09794.9 KFQ92520.1 - 0.0043 15.8 0.0 0.0084 14.8 0.0 1.5 1 0 0 1 1 1 1 Transport protein Avl9 RAM PF15320.6 KFQ92520.1 - 0.17 12.5 0.1 0.42 11.3 0.1 1.6 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein Arf PF00025.21 KFQ92521.1 - 6.5e-73 243.9 0.2 7e-73 243.8 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFQ92521.1 - 1.5e-14 53.8 0.0 1.8e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KFQ92521.1 - 2.4e-14 53.3 0.0 2.6e-14 53.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ92521.1 - 3.1e-14 53.2 0.0 4.7e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KFQ92521.1 - 2.6e-11 43.3 0.9 1.6e-09 37.4 0.2 2.4 1 1 1 2 2 2 1 G-protein alpha subunit Gtr1_RagA PF04670.12 KFQ92521.1 - 1e-10 41.4 0.0 1.2e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFQ92521.1 - 1e-05 25.6 0.0 1.5e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KFQ92521.1 - 0.017 14.4 0.1 0.026 13.8 0.1 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase CRISPR_Cas2 PF09827.9 KFQ92521.1 - 0.022 14.9 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 CRISPR associated protein Cas2 LepB_N PF18640.1 KFQ92521.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 LepB N-terminal domain AAA_18 PF13238.6 KFQ92521.1 - 0.16 12.5 0.1 0.33 11.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain Exo_endo_phos PF03372.23 KFQ92522.1 - 7.5e-22 78.0 0.0 1.8e-21 76.8 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AAA_6 PF12774.7 KFQ92523.1 - 3.7e-158 525.7 0.1 6.8e-155 515.0 0.0 3.1 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KFQ92523.1 - 2.1e-142 475.0 12.3 2.1e-142 475.0 12.3 2.8 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 KFQ92523.1 - 5.8e-117 390.3 0.0 1.9e-116 388.6 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 KFQ92523.1 - 8e-102 340.0 0.8 4.2e-101 337.6 0.0 2.7 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KFQ92523.1 - 4.4e-90 300.6 0.7 4.4e-90 300.6 0.7 3.5 5 0 0 5 5 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 KFQ92523.1 - 5.7e-86 286.7 0.1 1.6e-83 278.7 0.0 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KFQ92523.1 - 7.9e-63 211.2 0.0 2.5e-62 209.5 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KFQ92523.1 - 7.6e-50 169.9 10.1 1.9e-49 168.6 10.1 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KFQ92523.1 - 2.4e-48 163.1 0.1 5.3e-47 158.8 0.0 3.3 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 KFQ92523.1 - 3.7e-31 107.9 0.2 7.8e-30 103.6 0.0 3.4 3 0 0 3 3 3 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KFQ92523.1 - 3.7e-17 62.6 0.0 3e-05 24.0 0.0 5.6 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KFQ92523.1 - 5.1e-17 61.9 1.0 2e-16 60.0 1.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 KFQ92523.1 - 3.1e-06 27.7 7.2 0.027 14.9 0.0 5.3 6 0 0 6 6 5 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFQ92523.1 - 4.6e-05 23.9 0.1 0.46 10.9 0.0 5.0 5 0 0 5 5 4 1 AAA ATPase domain AAA_22 PF13401.6 KFQ92523.1 - 9e-05 22.8 0.0 1 9.6 0.0 5.1 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.22 KFQ92523.1 - 0.00042 20.7 0.6 5.3 7.5 0.0 4.5 5 0 0 5 5 3 1 RNA helicase AAA_24 PF13479.6 KFQ92523.1 - 0.0091 15.7 0.3 11 5.7 0.0 3.6 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 KFQ92523.1 - 0.045 12.8 0.1 0.21 10.6 0.0 2.2 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_30 PF13604.6 KFQ92523.1 - 0.12 12.1 0.0 6.9 6.3 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KFQ92523.1 - 0.2 12.2 2.4 1.2 9.7 0.0 3.7 4 0 0 4 4 2 0 AAA domain ABC_tran PF00005.27 KFQ92523.1 - 1 9.9 3.1 19 5.8 0.0 3.9 3 0 0 3 3 3 0 ABC transporter Ank_2 PF12796.7 KFQ92524.1 - 2.7e-45 152.8 5.3 1.2e-13 51.5 0.0 6.1 1 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ92524.1 - 2.7e-39 133.0 6.0 4.2e-10 40.0 0.0 8.3 6 1 1 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ92524.1 - 1.1e-37 123.7 10.4 6.9e-05 22.9 0.0 10.8 11 0 0 11 11 11 7 Ankyrin repeat Ank PF00023.30 KFQ92524.1 - 1.6e-31 107.4 9.6 7.6e-05 23.0 0.0 9.5 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 KFQ92524.1 - 7.6e-19 67.5 15.0 1.5e-05 25.1 0.0 8.2 3 2 7 10 10 10 6 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFQ92524.1 - 1.6e-10 41.1 5.0 9.6e-10 38.7 5.5 2.1 2 0 0 2 2 2 1 SOCS box BAR_3 PF16746.5 KFQ92525.1 - 5.2e-55 186.8 13.0 5.2e-55 186.8 13.0 2.2 2 0 0 2 2 2 1 BAR domain of APPL family PID PF00640.23 KFQ92525.1 - 3.1e-12 46.7 0.3 1.7e-11 44.3 0.0 2.5 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PH PF00169.29 KFQ92525.1 - 1.5e-07 31.9 0.1 6.9e-06 26.5 0.0 2.8 2 0 0 2 2 2 1 PH domain PTB PF08416.13 KFQ92525.1 - 0.0025 18.0 0.0 0.0077 16.4 0.0 1.8 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PH_9 PF15410.6 KFQ92525.1 - 0.014 15.8 0.8 0.069 13.5 0.0 2.6 3 0 0 3 3 3 0 Pleckstrin homology domain Gemin6 PF06372.12 KFQ92525.1 - 0.12 11.9 1.4 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 Gemin6 protein Homeodomain PF00046.29 KFQ92526.1 - 5.3e-24 83.8 1.8 2.5e-23 81.7 0.8 2.2 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KFQ92526.1 - 0.0037 17.1 0.3 0.0082 16.0 0.1 1.7 2 0 0 2 2 2 1 Homeobox KN domain IL17R_D_N PF16742.5 KFQ92527.1 - 5.8e-64 213.6 0.0 1.2e-63 212.6 0.0 1.6 1 0 0 1 1 1 1 N-terminus of interleukin 17 receptor D SEFIR PF08357.11 KFQ92527.1 - 2.7e-56 190.0 0.8 5.2e-56 189.1 0.8 1.5 1 0 0 1 1 1 1 SEFIR domain TIR_2 PF13676.6 KFQ92527.1 - 0.0013 19.3 0.0 0.0037 17.9 0.0 1.8 1 1 0 1 1 1 1 TIR domain fn3 PF00041.21 KFQ92527.1 - 0.023 15.1 0.0 5 7.6 0.0 2.7 3 0 0 3 3 3 0 Fibronectin type III domain DUF2141 PF09912.9 KFQ92527.1 - 0.089 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2141) DUF1863 PF08937.11 KFQ92527.1 - 0.17 12.2 0.2 0.57 10.5 0.2 1.9 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) RhoGEF PF00621.20 KFQ92528.1 - 2.4e-39 135.5 0.1 4.8e-39 134.5 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 KFQ92528.1 - 2e-06 27.9 0.5 1.8e-05 24.9 0.5 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFQ92528.1 - 0.00042 20.8 0.0 0.001 19.6 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 KFQ92528.1 - 0.00061 19.6 0.2 0.0074 16.1 0.1 2.6 1 1 1 2 2 2 1 Pleckstrin homology domain PH_16 PF17838.1 KFQ92528.1 - 0.023 14.5 0.2 6.5 6.6 0.0 2.6 2 0 0 2 2 2 0 PH domain zf-Di19 PF05605.12 KFQ92528.1 - 0.92 9.9 3.6 0.37 11.1 0.4 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF3715 PF12509.8 KFQ92529.1 - 1.9e-55 187.0 0.0 5.4e-55 185.5 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3715) CCDC66 PF15236.6 KFQ92530.1 - 6.1e-51 172.3 38.6 6.1e-51 172.3 38.6 4.3 5 0 0 5 5 5 1 Coiled-coil domain-containing protein 66 DUF2285 PF10074.9 KFQ92530.1 - 0.25 12.0 8.1 0.63 10.7 0.2 3.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2285) RVT_1 PF00078.27 KFQ92531.1 - 0.004 16.7 0.0 0.0077 15.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 7tm_4 PF13853.6 KFQ92532.1 - 2.8e-34 119.1 7.0 3.3e-34 118.9 7.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ92532.1 - 6.3e-30 104.4 5.7 7.9e-30 104.1 5.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ92532.1 - 0.019 14.4 10.7 0.026 13.9 10.7 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFQ92532.1 - 0.055 13.1 9.5 0.11 12.1 9.5 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx I-set PF07679.16 KFQ92533.1 - 1e-12 47.9 0.0 2.1e-12 46.9 0.0 1.6 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ92533.1 - 2.1e-12 47.5 0.0 3.7e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.21 KFQ92533.1 - 9e-08 32.4 0.0 0.0071 16.7 0.0 2.5 2 0 0 2 2 2 2 Fibronectin type III domain ig PF00047.25 KFQ92533.1 - 9.8e-08 32.1 0.0 1.6e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFQ92533.1 - 1.1e-06 28.9 0.0 2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFQ92533.1 - 2.5e-06 27.6 0.0 0.003 17.7 0.0 2.5 2 1 1 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFQ92533.1 - 0.0048 16.9 0.0 0.011 15.8 0.0 1.6 1 1 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFQ92533.1 - 0.01 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain MFS_1 PF07690.16 KFQ92535.1 - 1.1e-38 133.1 32.6 2.5e-33 115.5 22.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KFQ92535.1 - 0.00037 18.9 0.8 0.0059 14.9 0.0 2.7 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 KFQ92535.1 - 0.45 9.3 18.2 0.15 10.9 10.8 2.5 2 1 0 2 2 2 0 MFS_1 like family TraB PF01963.17 KFQ92537.1 - 7.1e-24 85.1 0.0 7.7e-24 85.0 0.0 1.0 1 0 0 1 1 1 1 TraB family TraB PF01963.17 KFQ92538.1 - 7.2e-38 131.0 0.0 8.2e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 TraB family RhoGAP PF00620.27 KFQ92541.1 - 1.4e-40 138.6 0.0 3e-40 137.5 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KFQ92541.1 - 3.4e-31 107.9 0.1 5.9e-11 42.8 0.1 5.1 4 1 0 4 4 4 3 PH domain ArfGap PF01412.18 KFQ92541.1 - 4.4e-25 88.0 0.0 4.9e-24 84.7 0.0 2.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH_11 PF15413.6 KFQ92541.1 - 3.2e-13 50.0 0.5 0.086 13.3 0.0 5.7 4 1 0 4 4 4 3 Pleckstrin homology domain PH_8 PF15409.6 KFQ92541.1 - 1.1e-10 41.6 0.4 0.0028 17.9 0.2 4.1 4 0 0 4 4 4 3 Pleckstrin homology domain PH_3 PF14593.6 KFQ92541.1 - 2.3e-09 37.3 0.3 7.5e-05 22.8 0.1 3.5 3 0 0 3 3 3 2 PH domain RA PF00788.23 KFQ92541.1 - 5.4e-09 36.6 0.2 1.3e-08 35.3 0.2 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PH_6 PF15406.6 KFQ92541.1 - 1.7e-08 34.7 0.0 0.00018 21.8 0.0 3.3 3 0 0 3 3 3 2 Pleckstrin homology domain PH_13 PF16652.5 KFQ92541.1 - 4.9e-05 23.2 0.1 0.6 9.9 0.0 3.2 3 0 0 3 3 3 2 Pleckstrin homology domain PH_2 PF08458.10 KFQ92541.1 - 0.00024 21.4 0.0 0.53 10.7 0.0 3.0 2 0 0 2 2 2 2 Plant pleckstrin homology-like region Thioredoxin_6 PF13848.6 KFQ92541.1 - 0.066 13.1 0.5 0.42 10.5 0.1 2.4 3 0 0 3 3 3 0 Thioredoxin-like domain BAH PF01426.18 KFQ92541.1 - 0.14 12.0 0.0 1.7 8.5 0.0 2.6 2 1 0 2 2 2 0 BAH domain DUF1033 PF06279.11 KFQ92541.1 - 0.19 11.9 1.6 1.1 9.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1033) Cornifin PF02389.15 KFQ92542.1 - 8.4 6.6 61.7 2.9 8.1 48.0 2.1 1 1 1 2 2 2 0 Cornifin (SPRR) family Arrestin_N PF00339.29 KFQ92543.1 - 1.3e-48 164.7 0.0 2e-43 147.9 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KFQ92543.1 - 9.2e-31 107.1 0.2 7.2e-30 104.2 0.1 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain BatD PF13584.6 KFQ92543.1 - 0.051 12.4 0.1 0.066 12.0 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance AP3B1_C PF14796.6 KFQ92543.1 - 0.051 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal LDB19 PF13002.7 KFQ92543.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like WD40 PF00400.32 KFQ92544.1 - 2.9e-08 34.2 1.9 0.016 16.1 0.2 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Reprolysin PF01421.19 KFQ92545.1 - 2.4e-41 141.9 3.2 2.4e-41 141.9 3.2 2.3 2 0 0 2 2 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.12 KFQ92545.1 - 1.4e-30 106.1 7.8 1.4e-30 106.1 7.8 4.0 3 2 0 3 3 1 1 ADAM cysteine-rich Pep_M12B_propep PF01562.19 KFQ92545.1 - 3e-22 79.3 0.1 3e-22 79.3 0.1 1.9 2 0 0 2 2 2 1 Reprolysin family propeptide Disintegrin PF00200.23 KFQ92545.1 - 2.9e-18 66.4 26.2 2.9e-18 66.4 26.2 4.8 3 1 0 3 3 2 1 Disintegrin Reprolysin_5 PF13688.6 KFQ92545.1 - 1.1e-15 58.3 2.0 2.4e-15 57.2 2.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFQ92545.1 - 2e-11 44.5 0.2 3.6e-11 43.7 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFQ92545.1 - 4.4e-07 29.7 0.1 7e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFQ92545.1 - 1.1e-05 25.4 0.5 2e-05 24.6 0.5 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 KFQ92545.1 - 0.0053 17.2 1.9 0.0053 17.2 1.9 6.8 3 2 2 6 6 5 2 ADAM cysteine-rich domain Astacin PF01400.24 KFQ92545.1 - 0.0077 15.9 0.1 0.019 14.6 0.1 1.6 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFQ92545.1 - 0.0089 15.9 0.2 0.016 15.1 0.2 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.8 KFQ92545.1 - 0.041 13.5 0.1 0.086 12.4 0.1 1.5 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase OATP PF03137.20 KFQ92546.1 - 6.2e-187 622.2 14.6 2.1e-184 613.8 14.6 2.0 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFQ92546.1 - 1.7e-21 76.6 30.7 3.1e-19 69.1 21.7 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.15 KFQ92546.1 - 9.3e-08 32.1 10.1 1.3e-07 31.6 9.1 1.8 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFQ92546.1 - 0.0003 20.7 3.5 0.00073 19.5 3.5 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain EMP70 PF02990.16 KFQ92546.1 - 3 6.4 6.8 0.76 8.4 2.9 1.9 2 0 0 2 2 2 0 Endomembrane protein 70 PGM_PMM_I PF02878.16 KFQ92548.1 - 2.7e-35 121.1 0.0 8.1e-35 119.5 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KFQ92548.1 - 9.1e-25 87.3 0.0 1.8e-23 83.1 0.0 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KFQ92548.1 - 3.2e-13 49.9 0.1 6.2e-13 49.0 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 KFQ92548.1 - 1.6e-07 31.4 0.1 9.8e-07 28.9 0.0 2.3 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain ISK_Channel PF02060.15 KFQ92549.1 - 1e-05 25.3 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Slow voltage-gated potassium channel LRR_4 PF12799.7 KFQ92551.1 - 2.2e-16 59.7 12.0 0.00074 19.9 0.3 4.5 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFQ92551.1 - 9.7e-11 41.3 19.5 7.6e-05 22.4 3.2 4.1 2 2 1 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 KFQ92551.1 - 6.1e-08 32.1 7.8 1 9.6 0.2 6.0 6 0 0 6 6 6 3 Leucine Rich repeat LRR_9 PF14580.6 KFQ92551.1 - 0.00038 20.0 0.4 0.51 9.8 0.1 2.6 2 1 0 2 2 2 2 Leucine-rich repeat LRR_2 PF07723.13 KFQ92551.1 - 0.072 13.8 0.2 46 4.9 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_1 PF00560.33 KFQ92551.1 - 0.15 12.7 11.8 57 4.8 0.2 6.4 6 1 0 6 6 6 0 Leucine Rich Repeat SPC25 PF06703.11 KFQ92552.1 - 2.6e-45 154.1 0.4 3.1e-45 153.9 0.4 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) BNR_2 PF13088.6 KFQ92553.1 - 1.6e-35 122.8 0.0 1.9e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR_3 PF13859.6 KFQ92553.1 - 2.1e-05 24.0 0.0 2.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 KFQ92553.1 - 0.016 15.1 0.8 0.016 15.1 0.8 3.1 3 0 0 3 3 3 0 BNR/Asp-box repeat CBM_10 PF02013.16 KFQ92553.1 - 0.52 10.8 6.7 7.9 7.0 0.1 2.6 2 0 0 2 2 2 0 Cellulose or protein binding domain P4Ha_N PF08336.11 KFQ92554.1 - 2.8e-22 79.2 0.0 4.4e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 KFQ92554.1 - 1.4e-15 57.9 0.1 2.6e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_6 PF12697.7 KFQ92555.1 - 1.5e-29 104.1 0.0 4.2e-29 102.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFQ92555.1 - 7.5e-14 52.0 0.0 2.3e-13 50.4 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFQ92555.1 - 1.8e-10 40.5 0.0 3.3e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KFQ92555.1 - 0.00012 22.2 0.0 0.00021 21.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 KFQ92555.1 - 0.003 17.3 0.1 0.006 16.3 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 KFQ92555.1 - 0.0037 17.1 0.0 0.0059 16.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KFQ92555.1 - 0.0096 15.8 0.9 3.1 7.5 0.9 2.4 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.20 KFQ92555.1 - 0.022 14.4 0.1 0.08 12.6 0.1 1.8 1 1 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 KFQ92555.1 - 0.026 14.4 0.1 0.066 13.1 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Mito_carr PF00153.27 KFQ92556.1 - 3.8e-66 219.1 1.2 3.8e-23 81.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Colicin_V PF02674.16 KFQ92556.1 - 0.13 12.2 1.7 0.37 10.7 0.3 2.3 1 1 0 2 2 2 0 Colicin V production protein DnaJ_C PF01556.18 KFQ92557.1 - 1.2e-37 129.3 0.0 1.5e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFQ92557.1 - 1.8e-20 72.8 0.4 3.5e-20 71.9 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.32 KFQ92558.1 - 1.6e-18 66.7 12.8 2e-05 25.2 0.0 6.2 7 0 0 7 7 7 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KFQ92558.1 - 0.0002 20.3 0.1 0.12 11.1 0.0 2.6 2 1 1 3 3 3 2 Nup133 N terminal like ANAPC4_WD40 PF12894.7 KFQ92558.1 - 0.027 14.8 0.0 20 5.5 0.0 3.6 2 2 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFQ92558.1 - 0.037 13.4 0.0 1.8 7.8 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain CHCH PF06747.13 KFQ92559.1 - 3.3e-06 27.1 3.1 4.5e-06 26.7 3.1 1.2 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.13 KFQ92559.1 - 0.0053 17.1 1.2 0.0092 16.3 1.2 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) CX9C PF16860.5 KFQ92559.1 - 0.0085 16.1 3.0 0.51 10.4 0.1 2.2 1 1 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KFQ92559.1 - 0.026 14.5 3.7 0.41 10.7 3.7 2.4 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like GCK PF07802.11 KFQ92559.1 - 0.16 12.4 2.4 1.1 9.7 0.4 2.0 1 1 1 2 2 2 0 GCK domain Ribosomal_S10 PF00338.22 KFQ92560.1 - 3.5e-17 62.4 0.6 4.3e-17 62.1 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e Ras PF00071.22 KFQ92561.1 - 2.1e-53 180.2 1.3 2.5e-53 180.0 1.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ92561.1 - 4.7e-32 110.7 0.3 7.5e-32 110.1 0.3 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ92561.1 - 7.6e-12 45.0 0.7 8.7e-12 44.8 0.7 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFQ92561.1 - 1.2e-05 25.0 0.8 2.3e-05 24.0 0.7 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFQ92561.1 - 0.00036 20.0 0.1 0.00047 19.6 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFQ92561.1 - 0.003 17.6 0.1 0.0055 16.8 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase PH PF00169.29 KFQ92563.1 - 7e-08 32.9 0.0 8.8e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFQ92563.1 - 0.0089 16.4 0.4 0.017 15.6 0.4 1.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KFQ92563.1 - 0.0099 16.1 0.1 0.084 13.2 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain TCRP1 PF14944.6 KFQ92565.1 - 3.5e-103 344.8 47.6 3.9e-103 344.7 47.6 1.0 1 0 0 1 1 1 1 Tongue Cancer Chemotherapy Resistant Protein 1 RELT PF12606.8 KFQ92567.1 - 3.2e-19 67.6 0.1 5.4e-19 66.9 0.1 1.4 1 0 0 1 1 1 1 Tumour necrosis factor receptor superfamily member 19 RhoGEF PF00621.20 KFQ92568.1 - 2e-43 148.8 3.1 3.3e-43 148.1 3.1 1.4 1 0 0 1 1 1 1 RhoGEF domain BBS2_Mid PF14783.6 KFQ92568.1 - 0.0008 19.4 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, middle region PIN_5 PF08745.11 KFQ92568.1 - 0.21 11.0 0.6 0.44 9.9 0.6 1.4 1 0 0 1 1 1 0 PINc domain ribonuclease SH3_1 PF00018.28 KFQ92569.1 - 1e-25 89.1 1.4 2.5e-12 46.2 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KFQ92569.1 - 1.1e-24 86.0 1.8 2.5e-13 49.6 0.2 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KFQ92569.1 - 3.4e-21 74.7 0.2 6.6e-11 41.7 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 KFQ92569.1 - 0.00011 22.4 0.3 0.00011 22.4 0.3 3.2 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain hSH3 PF14603.6 KFQ92569.1 - 0.0012 19.2 0.1 0.0078 16.6 0.0 2.3 2 0 0 2 2 2 1 Helically-extended SH3 domain SH3_3 PF08239.11 KFQ92569.1 - 0.0031 17.8 0.5 0.007 16.6 0.1 1.9 2 0 0 2 2 2 1 Bacterial SH3 domain Vac14_Fab1_bd PF12755.7 KFQ92569.1 - 0.068 13.8 1.4 0.22 12.2 0.3 2.2 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region H-kinase_dim PF02895.14 KFQ92569.1 - 0.14 12.5 3.0 6.5 7.2 0.1 3.5 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain SseC PF04888.12 KFQ92569.1 - 7.9 6.0 8.7 9.6 5.7 0.9 2.4 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family Ribosomal_S3_C PF00189.20 KFQ92570.1 - 3e-23 82.1 0.2 1.1e-22 80.3 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KFQ92570.1 - 1.7e-11 43.8 0.1 2.7e-11 43.1 0.1 1.3 1 0 0 1 1 1 1 KH domain GDPD PF03009.17 KFQ92571.1 - 8.1e-21 74.9 0.0 5.4e-18 65.6 0.0 2.2 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KFQ92571.1 - 0.1 13.1 0.0 0.26 11.8 0.0 1.8 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Leader_Thr PF08254.11 KFQ92571.1 - 0.31 10.8 3.7 0.76 9.6 3.7 1.7 1 0 0 1 1 1 0 Threonine leader peptide Kelch_1 PF01344.25 KFQ92572.1 - 2.1e-46 155.2 13.0 3.6e-11 42.4 0.0 7.6 6 2 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFQ92572.1 - 6.3e-38 127.8 8.9 3.4e-08 33.5 0.1 6.4 4 1 2 6 6 6 5 Kelch motif BACK PF07707.15 KFQ92572.1 - 4.8e-33 113.3 0.7 1.8e-32 111.5 0.5 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 KFQ92572.1 - 1.7e-29 100.6 7.0 2.1e-05 24.3 0.0 6.7 6 0 0 6 6 6 5 Kelch motif BTB PF00651.31 KFQ92572.1 - 2.4e-29 101.8 0.0 5.1e-29 100.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 KFQ92572.1 - 2.3e-21 75.5 10.9 0.0004 20.3 0.0 7.0 5 2 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KFQ92572.1 - 5.2e-18 64.9 5.6 0.001 19.3 0.1 6.2 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KFQ92572.1 - 3.9e-14 52.3 9.6 0.028 14.4 0.0 6.3 6 0 0 6 6 6 4 Kelch motif DUF3342 PF11822.8 KFQ92572.1 - 0.00014 22.0 0.0 0.0019 18.3 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3342) STOP PF05217.12 KFQ92573.1 - 2 8.8 4.6 1 9.7 0.8 2.2 2 0 0 2 2 2 0 STOP protein DDA1 PF10172.9 KFQ92574.1 - 0.47 10.8 2.4 8.6 6.7 0.1 2.6 2 0 0 2 2 2 0 Det1 complexing ubiquitin ligase DAGAT PF03982.13 KFQ92575.1 - 2.2e-119 397.8 0.0 2.6e-119 397.5 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DAGAT PF03982.13 KFQ92576.1 - 3e-142 472.8 0.0 3.7e-142 472.5 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 KFQ92576.1 - 0.0033 17.1 0.0 0.0066 16.1 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Atg14 PF10186.9 KFQ92578.1 - 1.7e-18 66.8 9.8 4.4e-18 65.4 9.7 1.6 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 KFQ92578.1 - 4.5e-11 42.3 8.0 8.9e-11 41.3 8.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting 38 C2 PF00168.30 KFQ92578.1 - 0.00028 21.1 0.0 0.001 19.3 0.0 1.9 2 0 0 2 2 2 1 C2 domain TPR_MLP1_2 PF07926.12 KFQ92578.1 - 0.062 13.4 10.7 0.13 12.3 10.7 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3585 PF12130.8 KFQ92578.1 - 0.17 12.0 12.2 0.4 10.8 12.2 1.6 1 0 0 1 1 1 0 Bivalent Mical/EHBP Rab binding domain FapA PF03961.13 KFQ92578.1 - 8.7 4.8 9.4 14 4.2 9.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A wnt PF00110.19 KFQ92579.1 - 1.2e-107 360.1 16.0 1.4e-107 359.9 16.0 1.0 1 0 0 1 1 1 1 wnt family DUF4371 PF14291.6 KFQ92580.1 - 1.8e-13 50.7 0.1 3.5e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFQ92580.1 - 6.3e-10 38.7 0.0 1.7e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region THAP PF05485.12 KFQ92580.1 - 1.1e-08 35.8 0.4 4.1e-08 34.0 0.4 2.1 1 0 0 1 1 1 1 THAP domain L27 PF02828.16 KFQ92580.1 - 0.031 14.0 0.0 6.7 6.6 0.0 2.7 2 0 0 2 2 2 0 L27 domain DUF3391 PF11871.8 KFQ92580.1 - 0.09 13.3 0.4 0.16 12.5 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF4746 PF15928.5 KFQ92580.1 - 0.11 11.9 4.6 0.25 10.7 4.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF659 PF04937.15 KFQ92580.1 - 0.64 9.9 2.9 12 5.7 0.0 3.6 5 0 0 5 5 5 0 Protein of unknown function (DUF 659) ENT PF03735.14 KFQ92581.1 - 1.1e-23 83.1 0.5 2e-23 82.2 0.5 1.5 1 0 0 1 1 1 1 ENT domain Guanylate_cyc PF00211.20 KFQ92582.1 - 9.1e-66 221.0 0.0 2.5e-65 219.6 0.0 1.8 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 KFQ92582.1 - 9.9e-62 209.1 0.0 1.4e-61 208.6 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 KFQ92582.1 - 1.3e-36 126.2 0.0 2.1e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ92582.1 - 1.7e-26 93.2 0.0 3.2e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 KFQ92582.1 - 2.8e-05 23.7 2.7 4.9e-05 22.9 2.7 1.4 1 0 0 1 1 1 1 Heme NO binding associated Catalase_C PF18011.1 KFQ92582.1 - 0.038 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 C-terminal domain found in long catalases Kinase-like PF14531.6 KFQ92582.1 - 0.055 12.8 0.0 0.13 11.5 0.0 1.5 2 0 0 2 2 2 0 Kinase-like LRR_8 PF13855.6 KFQ92583.1 - 5.8e-38 128.5 29.3 4.1e-12 45.7 2.4 6.5 4 2 2 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFQ92583.1 - 3.1e-21 75.1 38.1 3.6e-05 24.0 2.3 7.4 4 2 5 9 9 9 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFQ92583.1 - 3.1e-12 46.6 0.1 1.9e-05 24.6 0.3 2.5 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFQ92583.1 - 8.4e-11 40.9 27.1 0.031 14.8 0.3 9.7 9 1 0 9 9 9 3 Leucine Rich Repeat LRR_6 PF13516.6 KFQ92583.1 - 1.2e-05 24.9 26.5 0.75 10.0 0.0 8.5 9 0 0 9 9 9 3 Leucine Rich repeat LRR_9 PF14580.6 KFQ92583.1 - 0.013 15.0 8.3 1.8 8.1 2.1 3.3 1 1 2 3 3 3 0 Leucine-rich repeat LRRNT PF01462.18 KFQ92583.1 - 0.12 12.1 3.1 0.43 10.3 0.8 2.9 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Ceramidase PF05875.12 KFQ92584.1 - 1.6e-78 263.7 14.4 2e-78 263.5 14.4 1.0 1 0 0 1 1 1 1 Ceramidase DUF2070 PF09843.9 KFQ92584.1 - 1.8 6.7 4.7 2.3 6.4 4.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Peptidase_C2 PF00648.21 KFQ92585.1 - 1.9e-123 411.2 0.8 2.6e-123 410.8 0.8 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KFQ92585.1 - 1e-37 129.5 0.0 1.7e-37 128.8 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III C2 PF00168.30 KFQ92585.1 - 3.9e-12 46.4 0.0 1.1e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 C2 domain Myosin_head PF00063.21 KFQ92587.1 - 2.8e-245 815.7 4.9 3.8e-245 815.3 4.9 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.17 KFQ92587.1 - 5.8e-64 213.3 0.1 5.2e-32 110.6 0.0 3.3 2 0 0 2 2 2 2 MyTH4 domain FERM_M PF00373.18 KFQ92587.1 - 7.7e-27 94.0 11.6 8e-19 68.2 0.0 4.6 5 0 0 5 5 4 2 FERM central domain IQ PF00612.27 KFQ92587.1 - 3.9e-16 57.3 23.4 0.00033 20.2 0.1 6.0 5 0 0 5 5 5 4 IQ calmodulin-binding motif FERM_N PF09379.10 KFQ92587.1 - 6.8e-09 35.6 0.2 0.0036 17.2 0.1 2.7 2 0 0 2 2 2 2 FERM N-terminal domain SH3_9 PF14604.6 KFQ92587.1 - 0.018 14.9 0.0 0.089 12.7 0.0 2.3 1 0 0 1 1 1 0 Variant SH3 domain PID PF00640.23 KFQ92587.1 - 0.036 14.1 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) SH3_1 PF00018.28 KFQ92587.1 - 0.043 13.4 1.6 0.46 10.1 0.1 2.9 3 0 0 3 3 3 0 SH3 domain AAA_16 PF13191.6 KFQ92587.1 - 0.05 14.0 0.5 0.36 11.2 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KFQ92587.1 - 0.058 13.7 3.7 0.18 12.1 0.0 3.6 3 1 1 4 4 4 0 AAA domain SH3_2 PF07653.17 KFQ92587.1 - 0.15 11.8 0.0 0.42 10.3 0.0 1.9 1 0 0 1 1 1 0 Variant SH3 domain DUF3752 PF12572.8 KFQ92587.1 - 0.2 12.2 8.2 0.49 10.9 8.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) ABC_tran PF00005.27 KFQ92587.1 - 0.26 11.8 2.2 0.32 11.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_11 PF13086.6 KFQ92587.1 - 0.56 9.9 2.6 18 5.0 3.0 2.3 2 0 0 2 2 2 0 AAA domain DUF4407 PF14362.6 KFQ92587.1 - 3.2 7.0 7.3 5.7 6.2 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GDPD PF03009.17 KFQ92588.1 - 2.9e-17 63.2 0.0 3.9e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CENP-T_C PF15511.6 KFQ92588.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TctB PF07331.11 KFQ92588.1 - 7.9 6.8 17.5 6.8e+02 0.5 17.4 2.4 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Pkinase PF00069.25 KFQ92589.1 - 8.1e-73 245.0 0.0 1.3e-72 244.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ92589.1 - 3.8e-47 160.7 0.0 6e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KFQ92589.1 - 3.5e-25 88.1 0.0 1.1e-24 86.5 0.0 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KFQ92589.1 - 1.5e-07 31.1 0.0 0.00024 20.5 0.0 2.4 1 1 1 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KFQ92589.1 - 1.7e-06 27.1 0.0 3.4e-06 26.1 0.0 1.6 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFQ92589.1 - 0.0058 16.6 0.0 0.12 12.2 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family DSHCT PF08148.12 KFQ92589.1 - 0.017 14.8 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 DSHCT (NUC185) domain Kdo PF06293.14 KFQ92589.1 - 0.039 13.3 0.0 0.097 12.0 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MIP PF00230.20 KFQ92590.1 - 2.1e-10 40.7 5.1 2.1e-10 40.7 5.1 1.8 1 1 1 2 2 2 2 Major intrinsic protein DUF2929 PF11151.8 KFQ92590.1 - 1.3 9.4 4.8 4.1 7.8 0.1 3.5 3 2 1 4 4 4 0 Protein of unknown function (DUF2929) Voldacs PF03517.13 KFQ92591.1 - 6e-32 110.7 1.6 8.5e-32 110.2 1.6 1.2 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling DUF498 PF04430.14 KFQ92592.1 - 7.9e-20 71.0 0.0 8.7e-20 70.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Indigoidine_A PF04227.12 KFQ92592.1 - 0.016 14.6 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Indigoidine synthase A like protein HflK_N PF12221.8 KFQ92592.1 - 0.092 12.8 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Bacterial membrane protein N terminal EspA PF03433.13 KFQ92592.1 - 0.14 11.9 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 EspA-like secreted protein HEAT PF02985.22 KFQ92593.1 - 1.3e-20 71.7 7.0 0.021 15.1 0.0 8.7 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.6 KFQ92593.1 - 1.6e-15 57.3 6.2 1.2e-05 25.6 0.1 5.2 4 1 2 6 6 6 2 HEAT repeats Adaptin_N PF01602.20 KFQ92593.1 - 5.1e-10 38.5 4.4 0.00044 19.0 0.1 3.2 2 1 1 3 3 3 3 Adaptin N terminal region Cnd1 PF12717.7 KFQ92593.1 - 7.1e-10 39.2 4.7 0.0022 18.1 0.5 4.2 2 1 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KFQ92593.1 - 4.2e-08 33.7 0.9 0.00049 20.6 0.1 4.6 4 2 1 5 5 4 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KFQ92593.1 - 2e-06 27.5 0.4 4.1 6.9 0.1 4.7 2 2 3 5 5 5 3 CLASP N terminal Cohesin_HEAT PF12765.7 KFQ92593.1 - 0.00017 21.8 0.5 0.19 12.1 0.0 4.4 5 0 0 5 5 5 1 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.7 KFQ92593.1 - 0.001 18.4 3.9 0.094 11.9 0.1 2.8 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 KFQ92593.1 - 0.002 18.3 3.8 0.8 9.9 0.1 4.6 2 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF445 PF04286.12 KFQ92593.1 - 0.013 15.4 2.7 0.36 10.6 0.1 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF445) HEAT_PBS PF03130.16 KFQ92593.1 - 0.1 13.4 0.5 41 5.3 0.0 4.8 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat DUF3338 PF11819.8 KFQ92593.1 - 0.11 12.5 0.2 1.9 8.4 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) MMS19_N PF14500.6 KFQ92593.1 - 0.36 10.4 4.4 5.9 6.4 0.0 3.9 3 2 1 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II BTB_2 PF02214.22 KFQ92594.1 - 7.7e-17 61.4 0.0 1.2e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain TNF PF00229.18 KFQ92594.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family Spot_14 PF07084.12 KFQ92595.1 - 1.2e-21 77.5 0.0 1.7e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Thyroid hormone-inducible hepatic protein Spot 14 Spot_14 PF07084.12 KFQ92596.1 - 1.8e-21 76.9 0.0 2.1e-21 76.7 0.0 1.0 1 0 0 1 1 1 1 Thyroid hormone-inducible hepatic protein Spot 14 NDUF_C2 PF06374.11 KFQ92597.1 - 1.4e-24 86.3 0.1 1.6e-24 86.2 0.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Alg6_Alg8 PF03155.15 KFQ92598.1 - 1.4e-173 578.3 31.2 1.6e-173 578.1 31.2 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family BTB_2 PF02214.22 KFQ92599.1 - 2.5e-21 75.8 0.0 5.5e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KFQ92599.1 - 6.9e-05 22.9 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain PH PF00169.29 KFQ92600.1 - 6.8e-19 68.3 0.3 3.1e-18 66.2 0.2 2.3 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KFQ92600.1 - 0.00013 22.3 3.9 0.00027 21.3 1.4 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 KFQ92600.1 - 0.028 14.2 0.4 0.26 11.1 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain PH_2 PF08458.10 KFQ92600.1 - 0.16 12.3 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 Plant pleckstrin homology-like region PH_3 PF14593.6 KFQ92600.1 - 0.19 11.9 0.3 0.59 10.3 0.3 1.8 1 1 0 1 1 1 0 PH domain Phage_TAC_5 PF08890.11 KFQ92600.1 - 0.19 11.7 0.1 0.37 10.8 0.1 1.4 1 0 0 1 1 1 0 Phage XkdN-like tail assembly chaperone protein, TAC tRNA-synt_2 PF00152.20 KFQ92601.1 - 7.4e-96 320.9 0.1 9.1e-96 320.6 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFQ92601.1 - 2.8e-10 40.0 0.0 4.7e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KFQ92601.1 - 0.0011 18.4 1.4 1.4 8.3 0.8 2.7 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 KFQ92601.1 - 0.063 13.2 0.1 0.42 10.6 0.1 2.1 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) Tox-GHH PF15636.6 KFQ92602.1 - 1e-20 73.5 2.3 1.8e-20 72.7 2.3 1.4 1 0 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF977 PF06163.11 KFQ92602.1 - 0.11 12.5 0.2 0.18 11.7 0.2 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) Avidin PF01382.17 KFQ92603.1 - 1.3e-28 99.7 0.8 1.5e-28 99.6 0.8 1.0 1 0 0 1 1 1 1 Avidin family IES5 PF17335.2 KFQ92604.1 - 0.013 15.8 1.3 0.019 15.2 1.3 1.2 1 0 0 1 1 1 0 Ino80 complex subunit 5 Alpha-2-MRAP_C PF06401.11 KFQ92604.1 - 0.013 15.4 2.9 0.018 15.0 2.9 1.1 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain SKA2 PF16740.5 KFQ92604.1 - 0.016 15.0 2.5 0.023 14.5 2.5 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Golgin_A5 PF09787.9 KFQ92604.1 - 0.018 14.6 5.0 0.022 14.2 5.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 SR-25 PF10500.9 KFQ92604.1 - 0.028 14.0 5.2 0.035 13.7 5.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein XhlA PF10779.9 KFQ92604.1 - 0.082 13.1 6.0 0.14 12.4 6.0 1.4 1 0 0 1 1 1 0 Haemolysin XhlA RP-C_C PF11800.8 KFQ92604.1 - 0.099 12.7 2.6 0.13 12.3 2.6 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4349 PF14257.6 KFQ92604.1 - 0.18 11.2 1.3 0.29 10.6 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) PA26 PF04636.13 KFQ92604.1 - 0.27 10.1 1.8 0.34 9.8 1.8 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4407 PF14362.6 KFQ92604.1 - 0.34 10.2 3.0 0.43 9.9 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PIEZO PF15917.5 KFQ92604.1 - 0.51 9.8 4.7 0.72 9.3 4.7 1.1 1 0 0 1 1 1 0 Piezo DUF4611 PF15387.6 KFQ92604.1 - 6.5 7.1 14.1 0.068 13.4 5.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) AA_permease_2 PF13520.6 KFQ92605.1 - 2.6e-56 191.3 42.8 3.3e-56 190.9 42.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFQ92605.1 - 5.1e-21 74.8 39.2 7.6e-21 74.2 39.2 1.2 1 0 0 1 1 1 1 Amino acid permease LRR_4 PF12799.7 KFQ92606.1 - 2.6e-15 56.3 19.7 4.3e-07 30.1 0.7 4.2 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFQ92606.1 - 3.2e-12 46.3 0.4 7e-08 32.2 1.4 3.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KFQ92606.1 - 5.4e-09 35.7 22.4 3.8e-07 29.8 7.2 3.4 1 1 2 3 3 3 3 Leucine rich repeat Endopep_inhib PF16800.5 KFQ92606.1 - 0.0018 18.3 4.7 0.006 16.5 0.3 3.4 3 0 0 3 3 3 1 IseA DL-endopeptidase inhibitor LRR_6 PF13516.6 KFQ92606.1 - 0.0023 17.8 16.8 0.34 11.1 0.5 4.4 3 1 1 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.33 KFQ92606.1 - 1.8 9.4 16.1 2.4 9.0 0.5 4.6 3 1 0 3 3 3 0 Leucine Rich Repeat E2F_CC-MB PF16421.5 KFQ92607.1 - 2.4e-30 104.7 0.2 3.6e-30 104.2 0.2 1.3 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 KFQ92607.1 - 3.2e-14 52.7 0.3 6.4e-14 51.8 0.3 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Carb_anhydrase PF00194.21 KFQ92608.1 - 7.5e-91 304.2 0.0 8.3e-91 304.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 KFQ92609.1 - 8e-91 304.1 0.0 9e-91 303.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 KFQ92610.1 - 5.9e-77 258.6 0.0 6.6e-77 258.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 KFQ92611.1 - 2.7e-92 308.9 0.0 3e-92 308.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase HECT PF00632.25 KFQ92612.1 - 1.2e-97 327.1 0.5 2.3e-97 326.2 0.5 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KFQ92612.1 - 2.9e-50 168.0 31.0 2.1e-13 50.1 1.5 4.6 4 0 0 4 4 4 4 WW domain C2 PF00168.30 KFQ92612.1 - 9.3e-12 45.2 0.1 2.4e-11 43.8 0.1 1.7 1 0 0 1 1 1 1 C2 domain DUF3439 PF11921.8 KFQ92612.1 - 6.4 6.8 6.3 9.6 6.2 4.7 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3439) TPR_17 PF13431.6 KFQ92613.1 - 8.1e-07 29.0 1.4 0.48 10.9 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ92613.1 - 1.8e-06 27.5 14.3 0.17 11.7 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ92613.1 - 4.8e-06 27.0 0.6 0.21 12.1 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ92613.1 - 3.6e-05 23.5 17.0 0.78 10.0 0.0 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ92613.1 - 0.0001 22.8 5.0 30 5.8 0.0 4.7 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ92613.1 - 0.0016 18.1 1.0 0.89 9.3 0.0 3.6 4 0 0 4 4 4 1 TPR repeat TPR_8 PF13181.6 KFQ92613.1 - 0.051 13.8 7.6 1.2 9.5 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ92613.1 - 0.38 11.0 7.0 1.1 9.6 0.6 3.3 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Copine PF07002.16 KFQ92614.1 - 3.6e-92 307.7 0.0 5.4e-92 307.2 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 KFQ92614.1 - 6.4e-30 103.5 0.4 3.4e-14 53.0 0.1 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 KFQ92614.1 - 1.1e-05 25.6 0.0 5.1e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 vWA found in TerF C terminus DUF3211 PF11485.8 KFQ92614.1 - 0.041 14.1 0.1 0.086 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3211) VWA PF00092.28 KFQ92614.1 - 0.049 13.9 0.0 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain S_100 PF01023.19 KFQ92615.1 - 1.1e-18 66.6 0.3 2.1e-18 65.7 0.1 1.6 2 0 0 2 2 2 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.32 KFQ92615.1 - 4.1e-08 32.2 1.0 1.1e-06 27.8 0.3 2.2 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KFQ92615.1 - 2.2e-06 28.0 0.1 2.6e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFQ92615.1 - 1.9e-05 24.2 0.6 0.012 15.4 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFQ92615.1 - 2.2e-05 23.7 1.5 0.00011 21.6 0.4 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KFQ92615.1 - 0.00084 19.1 1.2 0.0031 17.3 1.1 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_11 PF08976.11 KFQ92615.1 - 0.0083 17.0 0.0 0.0096 16.8 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 KFQ92615.1 - 0.093 12.7 0.0 0.096 12.6 0.0 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Nicastrin PF05450.15 KFQ92616.1 - 3.8e-71 239.3 0.3 5.6e-71 238.7 0.3 1.2 1 0 0 1 1 1 1 Nicastrin Ncstrn_small PF18266.1 KFQ92616.1 - 1.4e-62 210.7 0.0 2.5e-62 209.8 0.0 1.5 1 0 0 1 1 1 1 Nicastrin small lobe Peptidase_M28 PF04389.17 KFQ92616.1 - 4.3e-09 36.4 0.0 6.5e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 HLH PF00010.26 KFQ92617.1 - 6.1e-19 67.7 0.2 6.1e-19 67.7 0.2 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain HTH_51 PF18558.1 KFQ92617.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.4 1 1 0 1 1 1 0 Helix-turn-helix domain DUF4703 PF15775.5 KFQ92617.1 - 1.7 8.4 5.1 2.5 7.9 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4703) Strabismus PF06638.11 KFQ92618.1 - 1.6e-249 828.7 0.2 1.9e-249 828.4 0.2 1.0 1 0 0 1 1 1 1 Strabismus protein CcmH PF03918.14 KFQ92619.1 - 0.14 11.4 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C biogenesis protein SKG6 PF08693.10 KFQ92619.1 - 0.14 11.5 1.6 0.28 10.6 1.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.20 KFQ92619.1 - 0.17 11.8 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Syndecan domain ig PF00047.25 KFQ92620.1 - 9e-05 22.6 0.1 0.32 11.2 0.0 3.4 3 0 0 3 3 3 1 Immunoglobulin domain V-set PF07686.17 KFQ92620.1 - 0.00053 20.1 0.0 0.019 15.1 0.0 2.4 2 1 0 2 2 2 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KFQ92620.1 - 0.00086 19.6 1.2 0.73 10.2 0.7 2.6 1 1 1 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 KFQ92620.1 - 0.0011 19.5 0.3 0.35 11.5 0.0 3.0 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFQ92620.1 - 0.01 15.9 0.0 0.31 11.1 0.0 2.9 3 1 0 3 3 3 0 Immunoglobulin I-set domain PKD PF00801.20 KFQ92620.1 - 0.068 13.0 0.1 0.81 9.6 0.0 2.6 2 1 0 2 2 2 0 PKD domain C2-set_2 PF08205.12 KFQ92620.1 - 0.095 12.8 0.7 0.94 9.6 0.0 2.4 1 1 1 2 2 2 0 CD80-like C2-set immunoglobulin domain SLAM PF06214.11 KFQ92621.1 - 0.016 15.2 0.1 0.05 13.6 0.1 1.8 2 0 0 2 2 2 0 Signaling lymphocytic activation molecule (SLAM) protein DUF5595 PF18077.1 KFQ92621.1 - 0.029 14.4 0.0 0.047 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) VMA21 PF09446.10 KFQ92621.1 - 0.064 13.4 0.3 0.13 12.4 0.3 1.6 1 1 0 1 1 1 0 VMA21-like domain Ig_3 PF13927.6 KFQ92621.1 - 1 10.0 3.7 1.2 9.8 1.3 2.2 2 0 0 2 2 2 0 Immunoglobulin domain UPF0258 PF06789.12 KFQ92622.1 - 4.7e-48 163.2 1.1 5.1e-48 163.1 1.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0258) DUF3377 PF11857.8 KFQ92622.1 - 0.054 13.4 0.3 0.091 12.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) EVI2A PF05399.11 KFQ92622.1 - 0.1 12.2 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) DUF4413 PF14372.6 KFQ92624.1 - 0.061 13.7 0.1 0.18 12.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Clat_adaptor_s PF01217.20 KFQ92625.1 - 9e-18 64.6 1.9 1.1e-17 64.3 1.9 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Histone PF00125.24 KFQ92626.1 - 4.9e-25 88.4 0.1 5.9e-25 88.1 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFQ92626.1 - 2.8e-06 27.5 0.4 7e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KFQ92626.1 - 0.011 16.2 0.0 0.023 15.2 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KFQ92626.1 - 0.012 15.7 0.1 0.014 15.4 0.1 1.1 1 0 0 1 1 1 0 YscO-like protein Histone PF00125.24 KFQ92627.1 - 6.8e-26 91.2 0.2 8.4e-26 90.9 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFQ92627.1 - 8.9e-07 29.1 0.7 1.8e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KFQ92627.1 - 0.0031 18.0 0.0 0.006 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KFQ92627.1 - 0.0034 17.4 0.3 0.0039 17.2 0.3 1.2 1 0 0 1 1 1 1 YscO-like protein Histone_H2A_C PF16211.5 KFQ92628.1 - 2.6e-20 71.8 1.1 4e-20 71.2 1.1 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFQ92628.1 - 1.6e-10 41.4 0.0 2.1e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone PF00125.24 KFQ92629.1 - 6.8e-26 91.2 0.2 8.4e-26 90.9 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFQ92629.1 - 8.9e-07 29.1 0.7 1.8e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KFQ92629.1 - 0.0031 18.0 0.0 0.006 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KFQ92629.1 - 0.0034 17.4 0.3 0.0039 17.2 0.3 1.2 1 0 0 1 1 1 1 YscO-like protein Histone_H2A_C PF16211.5 KFQ92630.1 - 4.1e-20 71.2 1.1 7.1e-20 70.4 1.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFQ92630.1 - 1.4e-15 57.8 0.0 1.8e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFQ92630.1 - 7.6e-05 22.9 0.0 0.0001 22.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MIEAP PF16026.5 KFQ92631.1 - 1.3e-60 205.0 0.0 1.5e-60 204.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondria-eating protein Phage_min_tail PF05939.13 KFQ92631.1 - 0.099 13.0 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Phage minor tail protein Arf PF00025.21 KFQ92632.1 - 1.5e-29 102.7 0.0 1.8e-29 102.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFQ92632.1 - 5.4e-09 36.3 0.0 6.9e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFQ92632.1 - 1.2e-06 28.1 0.0 1.4e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KFQ92632.1 - 1.5e-06 27.9 0.0 1.7e-06 27.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KFQ92632.1 - 0.00019 20.9 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KFQ92632.1 - 0.00088 18.5 0.8 0.071 12.3 0.0 2.1 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 KFQ92632.1 - 0.00094 19.3 0.0 0.0033 17.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 KFQ92632.1 - 0.0027 18.1 0.0 0.004 17.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFQ92632.1 - 0.0098 16.3 0.1 0.016 15.6 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KFQ92632.1 - 0.013 15.7 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KFQ92632.1 - 0.014 15.0 0.0 0.18 11.4 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KFQ92632.1 - 0.015 15.6 0.0 0.021 15.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFQ92632.1 - 0.021 15.3 0.3 0.21 12.1 0.3 2.0 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 KFQ92632.1 - 0.024 14.6 0.1 0.37 10.7 0.1 2.1 1 1 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 KFQ92632.1 - 0.057 13.4 0.0 0.078 13.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFQ92632.1 - 0.062 12.8 0.0 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KFQ92632.1 - 0.1 12.3 0.0 3.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 KFQ92632.1 - 0.11 12.9 0.1 0.27 11.6 0.1 1.7 1 1 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.17 KFQ92632.1 - 0.11 12.2 0.0 4.9 6.9 0.1 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein 7tm_1 PF00001.21 KFQ92634.1 - 1.7e-21 76.8 5.0 1.9e-21 76.6 5.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFQ92634.1 - 0.00045 19.6 1.8 0.00062 19.2 1.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw O-ag_pol_Wzy PF14296.6 KFQ92634.1 - 0.0032 16.2 4.3 0.0055 15.4 3.6 1.6 1 1 1 2 2 2 1 O-antigen polysaccharide polymerase Wzy Anticodon_1 PF08264.13 KFQ92634.1 - 0.02 14.8 0.3 0.044 13.7 0.2 1.7 1 1 0 1 1 1 0 Anticodon-binding domain of tRNA DUF443 PF04276.12 KFQ92634.1 - 0.027 14.3 0.9 0.043 13.6 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF443) DUF1129 PF06570.11 KFQ92634.1 - 0.098 12.1 0.3 0.15 11.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2975 PF11188.8 KFQ92634.1 - 8.9 6.2 7.0 26 4.7 7.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) 7tm_1 PF00001.21 KFQ92635.1 - 3.2e-46 157.8 24.4 4.7e-46 157.3 24.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFQ92635.1 - 0.00055 19.3 22.3 0.0042 16.4 1.4 2.3 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw Man-6-P_recep PF02157.15 KFQ92635.1 - 0.12 11.4 0.2 0.25 10.4 0.2 1.4 1 0 0 1 1 1 0 Mannose-6-phosphate receptor DUF4729 PF15866.5 KFQ92635.1 - 0.64 9.3 3.0 0.32 10.3 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4729) DUF4006 PF13179.6 KFQ92637.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF4006) ComGF PF15980.5 KFQ92637.1 - 0.017 15.5 0.0 0.038 14.3 0.0 1.6 1 1 0 1 1 1 0 Putative Competence protein ComGF CnrY PF17524.2 KFQ92637.1 - 0.02 15.1 0.0 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 Anti-sigma factor CnrY V-set PF07686.17 KFQ92637.1 - 0.085 13.0 0.1 0.16 12.2 0.0 1.5 2 0 0 2 2 2 0 Immunoglobulin V-set domain RPOL_N PF14700.6 KFQ92637.1 - 0.12 11.7 0.0 4.4 6.6 0.0 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal Septin PF00735.18 KFQ92638.1 - 1.2e-101 339.7 0.9 1.4e-101 339.5 0.9 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFQ92638.1 - 3.2e-10 40.1 0.1 7e-10 39.0 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFQ92638.1 - 3.4e-07 30.3 1.4 3.2e-06 27.1 0.6 2.3 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KFQ92638.1 - 7.7e-06 25.6 1.1 0.00011 21.8 0.2 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KFQ92638.1 - 1.1e-05 24.9 0.1 1.9e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KFQ92638.1 - 2.2e-05 24.6 2.1 0.0058 16.7 0.7 2.3 1 1 1 2 2 2 2 Dynamin family Roc PF08477.13 KFQ92638.1 - 4.5e-05 23.7 0.0 9.7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFQ92638.1 - 8.6e-05 22.2 0.2 0.00033 20.3 0.0 2.1 2 0 0 2 2 2 1 Ras family AAA_16 PF13191.6 KFQ92638.1 - 0.00063 20.2 0.0 0.0013 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.20 KFQ92638.1 - 0.0013 18.0 1.3 0.0024 17.1 1.2 1.5 1 1 0 1 1 1 1 G-protein alpha subunit AAA_24 PF13479.6 KFQ92638.1 - 0.0016 18.2 0.1 0.0083 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFQ92638.1 - 0.0017 18.6 0.0 0.0033 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain IIGP PF05049.13 KFQ92638.1 - 0.0019 17.4 1.0 0.019 14.0 0.0 2.3 3 0 0 3 3 3 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 KFQ92638.1 - 0.0019 18.7 1.3 0.006 17.1 1.3 1.7 1 1 0 2 2 2 1 ABC transporter NB-ARC PF00931.22 KFQ92638.1 - 0.0064 15.7 0.0 0.0088 15.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Gtr1_RagA PF04670.12 KFQ92638.1 - 0.0099 15.2 0.2 0.14 11.5 0.0 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 KFQ92638.1 - 0.01 15.2 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_15 PF13175.6 KFQ92638.1 - 0.011 15.5 1.4 0.018 14.8 1.4 1.2 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 KFQ92638.1 - 0.012 15.4 0.3 0.16 11.7 0.1 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 KFQ92638.1 - 0.014 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KFQ92638.1 - 0.016 14.7 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KFQ92638.1 - 0.019 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Arf PF00025.21 KFQ92638.1 - 0.032 13.7 0.1 0.064 12.7 0.1 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_14 PF13173.6 KFQ92638.1 - 0.041 13.9 0.1 0.086 12.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KFQ92638.1 - 0.045 13.3 0.2 0.13 11.8 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Ploopntkinase3 PF18751.1 KFQ92638.1 - 0.051 13.5 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Sigma54_activat PF00158.26 KFQ92638.1 - 0.061 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_32 PF13654.6 KFQ92638.1 - 0.08 11.7 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KFQ92638.1 - 0.095 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein RNA_helicase PF00910.22 KFQ92638.1 - 0.12 12.8 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.13 KFQ92638.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CBM_10 PF02013.16 KFQ92639.1 - 0.43 11.1 5.1 0.58 10.7 5.1 1.2 1 0 0 1 1 1 0 Cellulose or protein binding domain TNRC6-PABC_bdg PF16608.5 KFQ92640.1 - 3.2e-105 352.0 36.8 2.6e-75 253.8 7.7 8.0 5 3 2 7 7 7 2 TNRC6-PABC binding domain M_domain PF12938.7 KFQ92640.1 - 5.7e-67 226.1 42.3 5.7e-67 226.1 42.3 6.5 4 1 4 8 8 8 1 M domain of GW182 Ago_hook PF10427.9 KFQ92640.1 - 2e-20 74.0 28.7 2e-20 74.0 28.7 10.9 3 2 5 8 8 8 1 Argonaute hook UBA PF00627.31 KFQ92640.1 - 4.7e-06 26.4 0.1 9.3e-06 25.4 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RRM_1 PF00076.22 KFQ92640.1 - 0.00014 21.6 0.0 0.00024 20.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFQ92640.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF2748 PF10871.8 KFQ92640.1 - 0.51 8.9 4.6 1.5 7.4 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2748) THOC7 PF05615.13 KFQ92640.1 - 3.2 8.0 8.2 5.9 7.2 8.2 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 Ras PF00071.22 KFQ92641.1 - 2.3e-38 131.4 0.0 2.6e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ92641.1 - 5.5e-16 58.9 0.0 7.4e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ92641.1 - 2e-09 37.1 0.0 2.3e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFQ92641.1 - 2.1e-05 24.0 0.0 3.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KFQ92641.1 - 4.6e-05 23.4 0.2 0.096 12.6 0.0 2.1 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFQ92641.1 - 5.1e-05 23.3 0.0 7.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFQ92641.1 - 0.00021 20.9 0.0 0.028 13.9 0.0 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KFQ92641.1 - 0.0056 17.0 0.2 0.038 14.3 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFQ92641.1 - 0.0058 17.0 0.2 0.013 15.9 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KFQ92641.1 - 0.023 14.6 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KFQ92641.1 - 0.023 14.6 0.0 0.08 12.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 KFQ92641.1 - 0.03 13.8 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region G-alpha PF00503.20 KFQ92641.1 - 0.04 13.1 0.0 0.054 12.7 0.0 1.2 1 1 0 1 1 1 0 G-protein alpha subunit Viral_helicase1 PF01443.18 KFQ92641.1 - 0.091 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PRELI PF04707.14 KFQ92642.1 - 1.1e-50 171.5 0.5 1.7e-50 170.9 0.5 1.3 1 0 0 1 1 1 1 PRELI-like family CRAL_TRIO PF00650.20 KFQ92642.1 - 4.9e-41 140.1 0.0 8.5e-41 139.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFQ92642.1 - 7.6e-06 26.0 0.1 2e-05 24.7 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain UNC-93 PF05978.16 KFQ92644.1 - 2.7e-51 173.4 14.6 2.7e-51 173.4 14.6 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KFQ92644.1 - 3.9e-11 42.5 38.5 1.4e-08 34.1 25.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily OAD_gamma PF04277.13 KFQ92644.1 - 0.12 13.0 0.1 0.12 13.0 0.1 2.4 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain OCIA PF07051.11 KFQ92644.1 - 0.12 12.4 0.6 1.6 8.8 0.1 2.6 2 0 0 2 2 2 0 Ovarian carcinoma immunoreactive antigen (OCIA) RRM_1 PF00076.22 KFQ92645.1 - 3e-22 78.2 0.0 4.1e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFQ92645.1 - 0.02 14.9 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KFQ92645.1 - 0.088 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFQ92645.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_8 PF11835.8 KFQ92645.1 - 0.24 11.6 0.0 0.68 10.2 0.0 1.8 1 0 0 1 1 1 0 RRM-like domain Methyltransf_16 PF10294.9 KFQ92646.1 - 2.3e-16 60.0 0.0 3e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase JmjC PF02373.22 KFQ92647.1 - 6.6e-30 103.9 0.0 1.3e-29 102.9 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KFQ92647.1 - 4.4e-14 52.8 0.1 9.2e-14 51.8 0.1 1.6 1 1 0 1 1 1 1 Cupin-like domain AF-4 PF05110.13 KFQ92647.1 - 0.11 10.6 14.2 0.15 10.1 14.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SR-25 PF10500.9 KFQ92647.1 - 9.5 5.8 21.4 18 4.8 21.1 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Glyco_transf_29 PF00777.18 KFQ92648.1 - 5.3e-77 258.8 0.0 7.3e-77 258.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Glyco_transf_29 PF00777.18 KFQ92649.1 - 6.4e-70 235.6 0.0 7.4e-70 235.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Globin PF00042.22 KFQ92650.1 - 3.1e-24 85.6 0.1 5.3e-24 84.9 0.1 1.4 1 0 0 1 1 1 1 Globin DUF592 PF04574.13 KFQ92650.1 - 0.076 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF592) Acetyltransf_1 PF00583.25 KFQ92651.1 - 6.2e-14 52.2 0.0 7.9e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFQ92651.1 - 4.9e-08 33.0 0.0 7.4e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFQ92651.1 - 3.8e-06 27.2 0.0 5.8e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2811 PF10929.8 KFQ92651.1 - 0.15 12.4 0.1 0.33 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) MobA_MobL PF03389.15 KFQ92651.1 - 0.23 11.2 0.1 0.31 10.7 0.1 1.1 1 0 0 1 1 1 0 MobA/MobL family UQ_con PF00179.26 KFQ92652.1 - 1.9e-23 82.7 0.0 5.1e-23 81.3 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme DAGK_cat PF00781.24 KFQ92653.1 - 5.6e-22 77.7 0.0 7.1e-22 77.4 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF3943 PF13084.6 KFQ92653.1 - 0.16 11.8 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3943) Pribosyl_synth PF14572.6 KFQ92654.1 - 3.6e-101 336.8 0.8 3.6e-101 336.8 0.8 1.5 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KFQ92654.1 - 1.6e-38 131.2 0.2 3.4e-38 130.2 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KFQ92654.1 - 1.8e-06 27.6 0.1 4.5e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF4795 PF16043.5 KFQ92655.1 - 0.00011 21.9 13.9 0.0006 19.5 1.1 3.6 3 1 1 4 4 4 2 Domain of unknown function (DUF4795) Spc7 PF08317.11 KFQ92655.1 - 0.0038 16.2 18.4 0.0066 15.4 4.9 3.1 3 1 0 3 3 3 2 Spc7 kinetochore protein zf-CpG_bind_C PF12269.8 KFQ92655.1 - 0.0062 16.3 1.9 0.021 14.6 0.5 2.1 2 0 0 2 2 2 1 CpG binding protein zinc finger C terminal domain Spectrin PF00435.21 KFQ92655.1 - 0.015 15.7 4.5 0.015 15.7 4.5 3.7 3 1 0 3 3 3 0 Spectrin repeat AIP3 PF03915.13 KFQ92655.1 - 0.025 13.7 4.8 0.045 12.9 4.8 1.5 1 1 0 1 1 1 0 Actin interacting protein 3 SHE3 PF17078.5 KFQ92655.1 - 0.029 14.1 0.2 0.029 14.1 0.2 1.9 3 0 0 3 3 3 0 SWI5-dependent HO expression protein 3 PCRF PF03462.18 KFQ92655.1 - 0.042 13.7 9.7 1.3 8.8 0.6 3.1 2 1 1 3 3 3 0 PCRF domain DUF948 PF06103.11 KFQ92655.1 - 0.065 13.5 6.1 1.1 9.5 0.2 3.7 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) CorA PF01544.18 KFQ92655.1 - 0.14 11.4 7.0 0.17 11.2 2.2 2.5 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF2383 PF09537.10 KFQ92655.1 - 0.21 11.9 6.8 30 5.0 0.0 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF2383) SKA2 PF16740.5 KFQ92655.1 - 1.7 8.5 16.2 5.4 6.8 0.5 4.2 3 2 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Not3 PF04065.15 KFQ92655.1 - 1.8 7.9 8.5 0.41 10.0 1.8 2.5 2 1 0 3 3 3 0 Not1 N-terminal domain, CCR4-Not complex component Muted PF14942.6 KFQ92655.1 - 1.9 8.8 10.8 0.35 11.2 2.8 3.1 2 2 1 3 3 3 0 Organelle biogenesis, Muted-like protein Sec34 PF04136.15 KFQ92655.1 - 2 8.3 7.0 0.65 9.9 0.9 2.7 2 1 1 3 3 3 0 Sec34-like family DIMCO_N PF16844.5 KFQ92655.1 - 2.3 8.6 8.7 4.8 7.6 0.1 3.4 3 1 0 3 3 3 0 Dinitrogenase iron-molybdenum cofactor, N-terminal DUF2730 PF10805.8 KFQ92655.1 - 2.8 8.1 9.8 1.4 9.0 0.3 3.9 3 2 2 5 5 5 0 Protein of unknown function (DUF2730) DUF2408 PF10303.9 KFQ92655.1 - 2.8 8.5 8.0 1.1 9.8 3.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) YlbD_coat PF14071.6 KFQ92655.1 - 3.4 7.9 6.7 13 6.0 0.0 3.1 2 1 1 3 3 3 0 Putative coat protein Spore_III_AB PF09548.10 KFQ92655.1 - 5.3 7.1 9.1 1.9 8.6 2.0 2.4 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Wbp11 PF09429.10 KFQ92655.1 - 5.7 7.4 11.7 2.6 8.5 3.0 3.4 2 2 1 3 3 3 0 WW domain binding protein 11 DUF4407 PF14362.6 KFQ92655.1 - 9.8 5.4 13.9 4.5 6.6 8.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) zf-C3HC4_3 PF13920.6 KFQ92657.1 - 3e-14 52.6 9.6 6e-14 51.6 9.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFQ92657.1 - 6.8e-07 29.1 10.2 1.5e-06 28.0 10.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KFQ92657.1 - 1.6e-05 25.1 11.5 4.4e-05 23.7 11.5 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFQ92657.1 - 0.001 19.0 9.9 0.0028 17.6 9.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFQ92657.1 - 0.012 15.4 11.5 0.029 14.2 11.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFQ92657.1 - 0.19 11.5 3.7 0.35 10.7 0.9 2.8 3 0 0 3 3 3 0 RING-like zinc finger zf-RING_4 PF14570.6 KFQ92657.1 - 1.1 9.1 8.3 2.5 7.9 8.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 KFQ92657.1 - 2.1 8.1 11.4 2.1 8.0 9.6 2.1 2 0 0 2 2 2 0 P-11 zinc finger Forkhead PF00250.18 KFQ92658.1 - 1.4e-36 124.6 0.1 2.5e-36 123.8 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain 7tm_1 PF00001.21 KFQ92659.1 - 7.4e-55 186.1 22.7 8.7e-55 185.9 22.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFQ92659.1 - 4.4e-13 49.2 19.2 1.4e-11 44.3 19.2 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 KFQ92659.1 - 4.6e-07 29.9 18.6 1.8e-06 27.9 18.6 1.8 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFQ92659.1 - 0.00016 21.4 25.0 0.0003 20.5 24.3 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx SecG PF03840.14 KFQ92659.1 - 0.014 15.5 1.9 1 9.5 0.0 3.4 3 0 0 3 3 3 0 Preprotein translocase SecG subunit SRP68 PF16969.5 KFQ92660.1 - 5.5e-155 517.5 13.1 6.2e-155 517.4 13.1 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 TPR_6 PF13174.6 KFQ92660.1 - 0.0012 19.3 3.1 0.82 10.4 0.2 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ92660.1 - 0.022 14.6 2.3 1.1 9.2 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF5340 PF17275.2 KFQ92660.1 - 0.31 11.2 6.4 0.77 9.9 0.3 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5340) TPR_2 PF07719.17 KFQ92660.1 - 0.37 11.0 11.5 0.41 10.9 0.3 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Plectin PF00681.20 KFQ92661.1 - 2e-50 168.4 1.0 7.6e-13 48.1 0.1 8.0 5 1 2 7 7 7 6 Plectin repeat SH3_10 PF17902.1 KFQ92661.1 - 4.9e-21 74.6 0.1 1.5e-20 73.0 0.1 2.0 1 0 0 1 1 1 1 SH3 domain Spectrin PF00435.21 KFQ92661.1 - 6e-06 26.7 12.0 0.00028 21.3 2.9 14.4 10 3 4 15 15 15 4 Spectrin repeat Phage_XkdX PF09693.10 KFQ92661.1 - 0.011 15.7 0.2 19 5.4 0.0 3.6 3 0 0 3 3 3 0 Phage uncharacterised protein (Phage_XkdX) Pkinase PF00069.25 KFQ92662.1 - 7.1e-80 268.2 0.0 8.2e-80 267.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ92662.1 - 3.7e-38 131.3 0.0 4.6e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFQ92662.1 - 1.6e-05 24.1 0.1 0.00054 19.0 0.1 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFQ92662.1 - 0.00052 19.4 0.9 0.087 12.1 0.1 2.4 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 KFQ92662.1 - 0.0029 17.6 0.5 0.012 15.5 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KFQ92662.1 - 0.059 12.7 0.1 0.16 11.3 0.1 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2322 PF10084.9 KFQ92662.1 - 0.085 12.9 0.0 0.42 10.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2322) Ten1_2 PF15490.6 KFQ92663.1 - 2.4e-43 146.6 0.0 2.7e-43 146.4 0.0 1.0 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit GFD1 PF17331.2 KFQ92663.1 - 0.071 13.3 0.4 0.11 12.7 0.4 1.3 1 0 0 1 1 1 0 GFD1 mRNA transport factor ACOX PF01756.19 KFQ92664.1 - 4.5e-69 231.6 1.3 1.9e-68 229.5 0.7 2.0 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KFQ92664.1 - 3.2e-27 95.6 0.8 1.4e-26 93.5 0.1 2.4 3 0 0 3 3 3 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KFQ92664.1 - 4.7e-12 45.9 0.0 1.2e-11 44.6 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain PBP PF01161.20 KFQ92666.1 - 3.4e-11 43.6 0.2 5.9e-11 42.8 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein SPRY PF00622.28 KFQ92667.1 - 3.2e-06 27.2 0.9 6.7e-06 26.2 0.9 1.5 1 0 0 1 1 1 1 SPRY domain PRY PF13765.6 KFQ92667.1 - 0.0016 18.1 0.0 0.004 16.8 0.0 1.7 1 0 0 1 1 1 1 SPRY-associated domain TBCC_N PF16752.5 KFQ92667.1 - 0.088 13.3 3.2 0.66 10.4 0.1 2.6 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain DUF848 PF05852.11 KFQ92667.1 - 0.17 12.0 2.3 0.28 11.3 2.3 1.4 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) GRAM PF02893.20 KFQ92668.1 - 6.3e-16 58.3 0.0 8.3e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.8 KFQ92668.1 - 0.019 15.1 0.0 0.03 14.5 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.6 KFQ92668.1 - 0.11 12.8 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial PH domain zf_CCCH_5 PF18384.1 KFQ92669.1 - 7.1e-21 74.0 13.3 7.1e-21 74.0 13.3 3.9 3 1 0 3 3 3 1 Unkempt Zinc finger domain 1 (Znf1) zf-CCCH PF00642.24 KFQ92669.1 - 7.3e-06 25.8 6.1 4.2e-05 23.3 1.0 7.1 8 1 0 8 8 7 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KFQ92669.1 - 0.00011 22.0 10.6 0.00011 22.0 10.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF3450 PF11932.8 KFQ92669.1 - 0.0003 20.2 5.4 0.00047 19.5 5.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) zf_CCCH_4 PF18345.1 KFQ92669.1 - 0.00043 20.2 0.5 0.039 14.0 0.0 6.3 6 1 0 6 6 6 2 Zinc finger domain Laminin_II PF06009.12 KFQ92669.1 - 0.0054 16.8 1.2 0.01 15.9 1.2 1.4 1 0 0 1 1 1 1 Laminin Domain II THOC7 PF05615.13 KFQ92669.1 - 0.009 16.3 0.6 0.009 16.3 0.6 1.6 2 0 0 2 2 1 1 Tho complex subunit 7 Fez1 PF06818.15 KFQ92669.1 - 0.0091 16.5 8.8 0.02 15.4 8.8 1.5 1 0 0 1 1 1 1 Fez1 Sds3 PF08598.11 KFQ92669.1 - 0.076 13.0 1.9 0.16 12.0 1.9 1.5 1 0 0 1 1 1 0 Sds3-like DUF2205 PF10224.9 KFQ92669.1 - 0.39 10.7 4.7 0.18 11.8 1.4 2.2 2 0 0 2 2 2 0 Short coiled-coil protein DUF3560 PF12083.8 KFQ92669.1 - 0.64 10.2 5.1 1.1 9.5 3.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) RRP36 PF06102.12 KFQ92669.1 - 0.84 9.6 7.6 0.78 9.7 4.3 2.3 2 1 0 2 2 2 0 rRNA biogenesis protein RRP36 Alanine_zipper PF11839.8 KFQ92669.1 - 1.4 9.3 7.9 2.7 8.4 7.9 1.5 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein Ribosomal_S27e PF01667.17 KFQ92669.1 - 1.6 8.5 7.3 4.2 7.2 7.3 1.6 1 0 0 1 1 1 0 Ribosomal protein S27 DUF3584 PF12128.8 KFQ92669.1 - 4.4 4.7 12.6 6.1 4.2 12.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Histone PF00125.24 KFQ92670.1 - 7.6e-54 181.6 1.6 8.5e-54 181.4 1.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KFQ92670.1 - 7.9e-05 22.7 0.2 0.00017 21.7 0.0 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KFQ92670.1 - 0.00015 22.3 2.4 0.00019 22.0 2.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 KFQ92670.1 - 0.00028 21.2 0.0 0.00042 20.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KFQ92670.1 - 0.054 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GHMP_kinases_C PF08544.13 KFQ92672.1 - 3.7e-15 56.1 0.0 8.3e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 KFQ92672.1 - 1.2e-13 51.0 0.4 3.8e-13 49.5 0.4 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain ASL_C2 PF14698.6 KFQ92672.1 - 0.17 12.6 1.4 1 10.2 0.2 2.4 1 1 1 2 2 2 0 Argininosuccinate lyase C-terminal Integrin_beta PF00362.18 KFQ92673.1 - 1.7e-103 345.6 0.0 2.8e-103 344.9 0.0 1.4 1 0 0 1 1 1 1 Integrin beta chain VWA domain fn3 PF00041.21 KFQ92673.1 - 3.4e-67 222.8 2.2 1.2e-17 64.0 0.2 4.5 4 0 0 4 4 4 4 Fibronectin type III domain Calx-beta PF03160.14 KFQ92673.1 - 2.8e-16 59.5 0.6 6.2e-16 58.4 0.0 2.0 2 0 0 2 2 2 1 Calx-beta domain Integrin_B_tail PF07965.12 KFQ92673.1 - 3.8e-16 59.3 7.7 3.8e-16 59.3 7.7 2.5 2 0 0 2 2 2 1 Integrin beta tail domain I-EGF_1 PF18372.1 KFQ92673.1 - 7.3e-11 42.0 55.3 7.3e-11 42.0 7.4 5.0 4 0 0 4 4 4 3 Integrin beta epidermal growth factor like domain 1 PSI_integrin PF17205.3 KFQ92673.1 - 1.6e-10 40.6 8.7 1.6e-10 40.6 8.7 3.9 4 0 0 4 4 4 1 Integrin plexin domain Pur_ac_phosph_N PF16656.5 KFQ92673.1 - 2e-09 37.9 0.0 0.06 13.9 0.0 5.6 4 2 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain EGF_2 PF07974.13 KFQ92673.1 - 5.8e-06 26.6 82.0 0.0019 18.5 11.3 5.3 5 0 0 5 5 5 4 EGF-like domain SEA PF01390.20 KFQ92673.1 - 0.0017 18.4 0.0 0.0052 16.8 0.0 1.9 1 0 0 1 1 1 1 SEA domain EGF_Tenascin PF18720.1 KFQ92673.1 - 0.45 10.6 47.8 0.029 14.4 3.9 4.9 4 0 0 4 4 4 0 Tenascin EGF domain HCNGP PF07818.13 KFQ92674.1 - 2.4e-34 117.8 0.3 4.1e-34 117.1 0.3 1.4 1 0 0 1 1 1 1 HCNGP-like protein Trp_DMAT PF11991.8 KFQ92674.1 - 0.055 12.9 0.1 0.078 12.4 0.1 1.2 1 0 0 1 1 1 0 Tryptophan dimethylallyltransferase RecQ5 PF06959.11 KFQ92675.1 - 6.7e-27 94.8 17.5 9.1e-27 94.4 16.4 1.9 1 1 0 1 1 1 1 RecQ helicase protein-like 5 (RecQ5) DEAD PF00270.29 KFQ92675.1 - 3.7e-20 72.4 0.1 7.4e-20 71.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFQ92675.1 - 5.1e-16 59.0 0.1 5.3e-12 46.1 0.0 2.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KFQ92675.1 - 4.3e-10 40.2 2.3 1.6e-09 38.4 2.3 2.1 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 KFQ92675.1 - 0.00011 22.3 0.0 0.00031 20.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TFIIS_M PF07500.14 KFQ92675.1 - 0.0043 17.5 0.0 0.018 15.5 0.0 2.1 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SRI PF08236.11 KFQ92675.1 - 0.086 13.0 0.3 0.086 13.0 0.3 2.5 3 0 0 3 3 3 0 SRI (Set2 Rpb1 interacting) domain DUF4713 PF15831.5 KFQ92676.1 - 1.3e-22 79.9 12.1 1.6e-22 79.7 12.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4713) DUF3593 PF12159.8 KFQ92676.1 - 0.0014 18.6 0.0 0.0017 18.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3593) Shisa PF13908.6 KFQ92676.1 - 0.0021 18.4 1.9 0.0021 18.4 1.9 1.0 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Corona_S2 PF01601.16 KFQ92676.1 - 0.046 12.2 4.9 0.047 12.2 4.9 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Prominin PF05478.11 KFQ92676.1 - 0.29 9.1 6.9 0.28 9.1 6.9 1.0 1 0 0 1 1 1 0 Prominin FAM163 PF15069.6 KFQ92676.1 - 2.1 8.8 8.1 2.7 8.4 8.1 1.2 1 0 0 1 1 1 0 FAM163 family MyTH4 PF00784.17 KFQ92677.1 - 5.1e-30 104.2 0.4 2.7e-29 101.8 0.1 2.3 2 0 0 2 2 2 1 MyTH4 domain FERM_M PF00373.18 KFQ92677.1 - 9e-12 45.4 3.2 2.1e-11 44.2 0.2 2.5 2 0 0 2 2 2 1 FERM central domain FERM_f0 PF16511.5 KFQ92677.1 - 0.016 15.5 0.4 0.091 13.1 0.0 2.3 3 0 0 3 3 3 0 N-terminal or F0 domain of Talin-head FERM SH3_2 PF07653.17 KFQ92678.1 - 5.4e-11 42.0 0.0 9.3e-11 41.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFQ92678.1 - 3.1e-06 26.9 0.0 5.6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFQ92678.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 SH3 domain Myosin_head PF00063.21 KFQ92679.1 - 8.3e-195 648.9 0.0 1e-194 648.6 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.17 KFQ92679.1 - 1.1e-20 74.1 0.0 4.7e-20 72.1 0.0 2.2 1 0 0 1 1 1 1 MyTH4 domain IQ PF00612.27 KFQ92679.1 - 1.2e-07 30.9 11.6 1.4e-05 24.4 2.0 3.0 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_16 PF13191.6 KFQ92679.1 - 0.00078 19.9 1.1 0.0071 16.7 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KFQ92679.1 - 0.02 15.1 0.0 0.076 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KFQ92679.1 - 0.021 13.9 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KFQ92679.1 - 0.036 13.3 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 KFQ92679.1 - 0.058 13.9 0.0 0.77 10.3 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 KFQ92679.1 - 0.07 13.3 0.0 0.28 11.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KFQ92679.1 - 0.089 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 KFQ92679.1 - 0.15 12.1 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Vinculin PF01044.19 KFQ92679.1 - 0.16 10.2 0.3 0.26 9.5 0.3 1.2 1 0 0 1 1 1 0 Vinculin family TPR_1 PF00515.28 KFQ92680.1 - 1.5e-37 125.9 26.8 4.5e-06 26.2 0.5 9.7 8 1 2 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ92680.1 - 1e-32 109.6 22.6 0.00025 20.9 0.4 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat DUF1736 PF08409.11 KFQ92680.1 - 1.5e-30 105.0 1.4 3.3e-30 103.9 1.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_8 PF13181.6 KFQ92680.1 - 1.3e-28 96.8 24.0 0.0043 17.2 0.0 9.4 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ92680.1 - 5.1e-24 84.4 22.2 7.6e-08 32.5 0.0 6.1 4 3 1 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ92680.1 - 2e-22 79.5 9.8 2.3e-05 24.9 2.1 6.1 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ92680.1 - 1.8e-20 72.3 15.4 0.00051 19.7 0.3 7.7 4 3 5 9 9 8 5 TPR repeat TPR_7 PF13176.6 KFQ92680.1 - 3.8e-16 57.8 14.2 0.0055 16.6 0.0 8.6 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ92680.1 - 1.8e-13 49.9 19.6 0.039 14.3 0.3 9.3 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ92680.1 - 6.5e-13 48.1 35.3 0.1 12.5 0.0 9.3 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ92680.1 - 3.1e-12 46.2 10.6 0.95 10.5 0.2 8.9 5 3 4 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ92680.1 - 2.7e-10 40.6 14.9 0.017 15.6 0.0 5.4 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 KFQ92680.1 - 2.1e-08 34.2 1.1 0.21 11.8 0.4 4.5 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFQ92680.1 - 4.8e-08 32.8 2.4 0.00021 20.8 0.0 4.0 1 1 3 4 4 4 1 MalT-like TPR region NARP1 PF12569.8 KFQ92680.1 - 3e-07 29.7 2.2 0.024 13.6 0.5 3.2 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 KFQ92680.1 - 3.2e-06 27.4 7.9 0.1 13.3 0.0 5.9 7 0 0 7 7 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 KFQ92680.1 - 4.1e-06 26.9 0.0 19 6.2 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 KFQ92680.1 - 8.2e-06 25.7 12.0 0.51 10.4 0.3 5.4 7 0 0 7 7 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ92680.1 - 2.9e-05 24.2 14.5 0.02 15.1 1.2 4.5 2 1 3 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 PMT PF02366.18 KFQ92680.1 - 0.00028 20.6 6.1 0.00028 20.6 6.1 1.8 2 0 0 2 2 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_2 PF13231.6 KFQ92680.1 - 0.00055 20.2 3.3 0.00055 20.2 3.3 2.6 3 0 0 3 3 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase FAT PF02259.23 KFQ92680.1 - 0.0016 17.7 2.5 0.024 13.8 0.6 2.4 1 1 1 2 2 2 1 FAT domain Coatomer_E PF04733.14 KFQ92680.1 - 0.002 17.6 2.9 1.9 7.8 0.3 3.2 2 1 0 3 3 3 2 Coatomer epsilon subunit TPR_21 PF09976.9 KFQ92680.1 - 0.002 17.9 2.8 6.5 6.4 0.0 4.4 1 1 2 4 4 4 0 Tetratricopeptide repeat-like domain TPR_15 PF13429.6 KFQ92680.1 - 0.0039 16.4 7.3 0.056 12.7 0.2 3.9 2 2 2 4 4 4 1 Tetratricopeptide repeat DUF389 PF04087.14 KFQ92680.1 - 0.053 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF389) Sel1 PF08238.12 KFQ92680.1 - 0.16 12.7 14.1 70 4.3 0.2 7.0 8 0 0 8 8 6 0 Sel1 repeat SNAP PF14938.6 KFQ92680.1 - 0.2 11.1 5.5 6.6 6.1 0.5 3.2 2 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP DUF2225 PF09986.9 KFQ92680.1 - 2.5 7.8 6.9 1.2 8.8 1.4 3.0 2 2 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) Pentapeptide_4 PF13599.6 KFQ92681.1 - 0.2 11.8 0.0 0.22 11.7 0.0 1.1 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) SNF PF00209.18 KFQ92682.1 - 6.5e-226 751.1 30.9 7.9e-226 750.8 30.9 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Tmemb_18A PF09771.9 KFQ92682.1 - 1.2 9.5 4.4 1 9.8 0.1 2.9 3 0 0 3 3 3 0 Transmembrane protein 188 IQ PF00612.27 KFQ92683.1 - 2.8e-06 26.6 0.1 7.1e-06 25.4 0.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Homeodomain PF00046.29 KFQ92684.1 - 6.9e-24 83.5 6.3 1.6e-23 82.3 6.3 1.6 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 KFQ92684.1 - 3.9e-09 36.0 3.2 9.2e-09 34.9 3.2 1.7 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 KFQ92684.1 - 0.0011 18.8 0.2 0.0035 17.2 0.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain RA PF00788.23 KFQ92685.1 - 5e-07 30.3 0.4 8e-06 26.4 0.0 2.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain Pro-NT_NN PF07421.11 KFQ92686.1 - 3.7e-65 219.2 2.1 4.1e-65 219.0 2.1 1.0 1 0 0 1 1 1 1 Neurotensin/neuromedin N precursor 7tm_1 PF00001.21 KFQ92688.1 - 1.7e-21 76.8 5.0 1.9e-21 76.6 5.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFQ92688.1 - 0.00044 19.6 1.8 0.00062 19.2 1.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw O-ag_pol_Wzy PF14296.6 KFQ92688.1 - 0.0032 16.2 4.0 0.0046 15.7 3.4 1.5 1 1 1 2 2 2 1 O-antigen polysaccharide polymerase Wzy Anticodon_1 PF08264.13 KFQ92688.1 - 0.021 14.8 0.3 0.054 13.4 0.2 1.6 1 1 1 2 2 2 0 Anticodon-binding domain of tRNA DUF443 PF04276.12 KFQ92688.1 - 0.027 14.3 0.9 0.049 13.4 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF443) DUF1129 PF06570.11 KFQ92688.1 - 0.098 12.1 0.3 0.15 11.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2975 PF11188.8 KFQ92688.1 - 8.9 6.2 7.0 26 4.7 7.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) 2OG-FeII_Oxy_3 PF13640.6 KFQ92689.1 - 5.9e-11 43.1 0.1 1.1e-10 42.3 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Oxygenase-NA PF09859.9 KFQ92689.1 - 0.03 13.8 0.3 0.7 9.4 0.3 2.5 1 1 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA Glyco_hydro_20 PF00728.22 KFQ92690.1 - 7.1e-11 42.1 0.6 1.6e-10 40.9 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain DUF3546 PF12066.8 KFQ92690.1 - 0.064 13.5 0.7 0.33 11.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3546) DUF4564 PF15169.6 KFQ92691.1 - 1.2e-84 282.6 0.0 1.4e-84 282.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4564) UbiA PF01040.18 KFQ92691.1 - 0.042 13.2 0.1 0.056 12.7 0.1 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family Fe_hyd_lg_C PF02906.14 KFQ92692.1 - 7.7e-70 235.3 0.1 1.4e-69 234.5 0.1 1.4 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 KFQ92692.1 - 1.3e-09 38.0 0.6 2.2e-09 37.3 0.0 1.8 2 0 0 2 2 2 1 Iron hydrogenase small subunit Forkhead PF00250.18 KFQ92694.1 - 5e-41 138.8 0.2 8.4e-41 138.1 0.2 1.4 1 0 0 1 1 1 1 Forkhead domain ANAPC4_WD40 PF12894.7 KFQ92695.1 - 8.2e-06 26.0 0.0 0.035 14.4 0.0 3.7 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFQ92695.1 - 0.022 15.6 4.5 0.62 11.0 0.0 4.0 4 1 1 5 5 5 0 WD domain, G-beta repeat DUF1513 PF07433.11 KFQ92695.1 - 0.077 12.1 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) PHTB1_N PF14727.6 KFQ92695.1 - 0.11 11.8 0.1 0.22 10.8 0.1 1.6 1 1 0 1 1 1 0 PTHB1 N-terminus DUF3761 PF12587.8 KFQ92695.1 - 0.17 12.3 0.1 0.43 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3761) Ras PF00071.22 KFQ92696.1 - 7e-41 139.5 0.0 9.8e-41 139.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ92696.1 - 9e-21 74.3 0.0 1.3e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SOCS_box PF07525.16 KFQ92696.1 - 7.8e-07 29.4 1.5 1.6e-06 28.3 1.5 1.6 1 0 0 1 1 1 1 SOCS box Arf PF00025.21 KFQ92696.1 - 7.1e-05 22.3 0.0 9.1e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Fructosamin_kin PF03881.14 KFQ92697.1 - 3.2e-69 233.3 0.3 1.1e-68 231.5 0.3 1.7 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KFQ92697.1 - 2.2e-06 27.8 0.0 2.9e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4763 PF15960.5 KFQ92697.1 - 0.036 13.4 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Fructosamin_kin PF03881.14 KFQ92698.1 - 1.3e-73 247.8 0.1 4.6e-73 245.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KFQ92698.1 - 1.3e-12 48.2 0.0 1.8e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFQ92698.1 - 0.00098 18.8 0.0 0.015 14.9 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Pkinase_Tyr PF07714.17 KFQ92698.1 - 0.019 14.2 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase TFCD_C PF12612.8 KFQ92699.1 - 2.3e-70 236.3 0.4 3.4e-69 232.5 0.0 3.0 4 0 0 4 4 4 1 Tubulin folding cofactor D C terminal HEAT_EZ PF13513.6 KFQ92699.1 - 7.8e-05 23.1 11.2 0.28 11.8 0.0 6.4 7 2 1 8 8 8 2 HEAT-like repeat HEAT PF02985.22 KFQ92699.1 - 0.00025 21.0 9.3 0.41 11.0 0.0 8.2 10 0 0 10 10 10 1 HEAT repeat Cnd1 PF12717.7 KFQ92699.1 - 0.0025 17.9 0.5 1.9 8.5 0.0 4.8 7 0 0 7 7 7 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFQ92699.1 - 0.0059 17.0 1.4 3.6 8.0 0.0 4.6 5 0 0 5 5 5 1 HEAT repeats STAG PF08514.11 KFQ92699.1 - 0.012 15.6 0.8 4.9 7.1 0.0 3.1 2 0 0 2 2 2 0 STAG domain HEAT_PBS PF03130.16 KFQ92699.1 - 0.9 10.4 4.8 34 5.5 0.0 5.3 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat zf-C2H2_7 PF15269.6 KFQ92700.1 - 1.8e-36 124.0 11.3 5.9e-36 122.3 11.3 2.0 1 0 0 1 1 1 1 Zinc-finger zf-H2C2_5 PF13909.6 KFQ92700.1 - 0.14 11.9 5.5 0.34 10.7 5.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFQ92700.1 - 2 9.0 10.9 1.2 9.7 5.9 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type Glycos_transf_2 PF00535.26 KFQ92701.1 - 2e-20 73.3 0.0 3.3e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KFQ92701.1 - 4.8e-07 29.9 0.0 5.8e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KFQ92701.1 - 3e-05 24.5 0.0 0.00037 21.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 KFQ92701.1 - 0.00027 20.5 0.0 0.00037 20.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NTR PF01759.21 KFQ92702.1 - 0.013 15.3 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 UNC-6/NTR/C345C module TIMP PF00965.17 KFQ92702.1 - 0.087 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Tissue inhibitor of metalloproteinase ABC_membrane PF00664.23 KFQ92704.1 - 6.1e-72 242.5 12.8 8.1e-72 242.2 12.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFQ92704.1 - 2.5e-36 125.2 0.1 5.3e-36 124.2 0.1 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFQ92704.1 - 7.4e-10 38.6 1.4 4.3e-08 32.9 1.5 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KFQ92704.1 - 0.00018 20.5 0.1 0.00097 18.0 0.0 2.0 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_16 PF13191.6 KFQ92704.1 - 0.00027 21.4 0.5 0.00085 19.7 0.2 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFQ92704.1 - 0.0004 20.7 0.3 0.0024 18.2 0.3 2.0 1 1 0 1 1 1 1 AAA domain DUF2207 PF09972.9 KFQ92704.1 - 0.0011 17.9 0.0 0.0011 17.9 0.0 2.4 2 1 0 2 2 1 1 Predicted membrane protein (DUF2207) Rad17 PF03215.15 KFQ92704.1 - 0.0027 17.6 0.2 0.006 16.5 0.1 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 KFQ92704.1 - 0.0044 16.9 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 KFQ92704.1 - 0.029 14.1 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KFQ92704.1 - 0.031 14.3 0.0 0.28 11.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 KFQ92704.1 - 0.037 13.2 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit IstB_IS21 PF01695.17 KFQ92704.1 - 0.038 13.7 0.1 6 6.6 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.29 KFQ92704.1 - 0.043 14.2 0.1 11 6.4 0.1 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 KFQ92704.1 - 0.051 13.8 0.5 0.57 10.5 0.5 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 KFQ92704.1 - 0.062 13.1 0.0 4.1 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFQ92704.1 - 0.08 12.7 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KFQ92704.1 - 0.08 12.2 0.2 2.8 7.2 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin DUF2098 PF09871.9 KFQ92704.1 - 0.13 12.6 0.1 0.5 10.7 0.0 1.9 2 0 0 2 2 1 0 Uncharacterized protein conserved in archaea (DUF2098) ABC_tran PF00005.27 KFQ92705.1 - 4.5e-32 111.4 0.0 5.1e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 KFQ92705.1 - 0.00095 19.4 0.0 0.0016 18.7 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KFQ92705.1 - 0.001 19.4 0.3 0.071 13.3 0.2 2.1 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.15 KFQ92705.1 - 0.0011 19.0 0.1 0.002 18.1 0.1 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain G-alpha PF00503.20 KFQ92705.1 - 0.0025 17.0 0.0 0.0026 17.0 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit ABC_ATPase PF09818.9 KFQ92705.1 - 0.0033 16.3 0.1 0.013 14.3 0.0 1.8 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_16 PF13191.6 KFQ92705.1 - 0.0045 17.4 0.1 0.0051 17.2 0.1 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KFQ92705.1 - 0.0047 17.4 0.1 0.18 12.2 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KFQ92705.1 - 0.0062 16.3 0.1 0.011 15.5 0.1 1.5 1 1 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.25 KFQ92705.1 - 0.0078 15.9 0.2 0.37 10.4 0.1 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.6 KFQ92705.1 - 0.019 14.7 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KFQ92705.1 - 0.03 14.2 0.5 0.073 13.0 0.3 1.6 1 1 0 1 1 1 0 RsgA GTPase DUF87 PF01935.17 KFQ92705.1 - 0.031 14.4 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain SMC_N PF02463.19 KFQ92705.1 - 0.031 13.7 0.2 0.75 9.2 0.2 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_19 PF13245.6 KFQ92705.1 - 0.032 14.6 0.3 0.086 13.2 0.3 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFQ92705.1 - 0.034 13.7 0.1 0.087 12.3 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 KFQ92705.1 - 0.051 13.3 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.18 KFQ92705.1 - 0.054 13.2 0.6 0.21 11.3 0.6 1.9 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_5 PF07728.14 KFQ92705.1 - 0.07 13.1 0.1 0.26 11.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KFQ92705.1 - 0.087 12.0 0.0 0.22 10.7 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF815) Carn_acyltransf PF00755.20 KFQ92706.1 - 4.9e-171 570.3 0.0 5.6e-171 570.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Thioesterase PF00975.20 KFQ92707.1 - 2.2e-42 145.7 0.0 2.6e-42 145.5 0.0 1.0 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 KFQ92707.1 - 0.00033 20.4 0.0 0.00058 19.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 KFQ92707.1 - 0.00045 20.1 0.0 0.0007 19.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KFQ92707.1 - 0.005 17.5 0.0 0.0059 17.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family GlgX_C PF18390.1 KFQ92707.1 - 0.028 14.2 0.0 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Glycogen debranching enzyme C-terminal domain Hydrolase_4 PF12146.8 KFQ92707.1 - 0.037 13.3 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 KFQ92707.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase ACBP PF00887.19 KFQ92708.1 - 3.7e-29 100.8 0.5 4e-29 100.7 0.5 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein JmjN PF02375.17 KFQ92708.1 - 0.04 13.9 1.1 1.4 8.9 0.1 2.2 2 0 0 2 2 2 0 jmjN domain RPEL PF02755.15 KFQ92708.1 - 0.34 10.7 0.3 0.34 10.7 0.3 1.8 2 0 0 2 2 2 0 RPEL repeat Ribosomal_L7Ae PF01248.26 KFQ92709.1 - 1.8e-08 34.0 0.0 4.5e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KFQ92709.1 - 4.2e-05 23.7 0.0 0.0022 18.0 0.0 2.2 2 0 0 2 2 2 2 RNase P subunit Pop3 NMT_C PF02799.15 KFQ92710.1 - 4.8e-82 274.5 0.2 6.3e-82 274.2 0.2 1.1 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KFQ92710.1 - 1.5e-76 255.6 0.0 3.3e-76 254.6 0.0 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 KFQ92710.1 - 0.00014 22.0 0.0 0.00026 21.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KFQ92710.1 - 0.03 14.4 0.0 0.071 13.2 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFQ92710.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Cadherin PF00028.17 KFQ92713.1 - 4.2e-84 277.1 7.5 7.6e-20 71.2 0.1 5.2 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFQ92713.1 - 1.2e-55 187.8 0.1 2.3e-55 186.9 0.1 1.4 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.12 KFQ92713.1 - 5.7e-06 26.1 0.0 0.96 9.3 0.0 4.6 4 1 0 4 4 4 2 Cadherin-like Cadherin_3 PF16184.5 KFQ92713.1 - 3.9e-05 23.6 5.3 0.82 9.7 0.1 5.0 5 0 0 5 5 5 2 Cadherin-like Cadherin_4 PF17803.1 KFQ92713.1 - 1.8 9.2 17.2 2.2 8.9 1.3 4.5 4 0 0 4 4 4 0 Bacterial cadherin-like domain PRY PF13765.6 KFQ92714.1 - 1.7e-22 78.8 0.3 2.8e-22 78.1 0.3 1.4 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.28 KFQ92714.1 - 3.1e-12 46.7 0.0 3.7e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 SPRY domain Opiods_neuropep PF01160.18 KFQ92714.1 - 0.00067 19.7 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Vertebrate endogenous opioids neuropeptide Ran_BP1 PF00638.18 KFQ92715.1 - 9.2e-14 51.7 0.0 1.7e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain SDF PF00375.18 KFQ92716.1 - 1.7e-132 442.2 29.0 1.9e-132 442.0 29.0 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family MT PF12777.7 KFQ92716.1 - 0.036 13.1 0.0 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor Lon_C PF05362.13 KFQ92717.1 - 1.7e-25 89.8 0.0 5.4e-25 88.2 0.0 1.9 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 KFQ92717.1 - 8.9e-25 87.6 0.0 3.6e-24 85.7 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 KFQ92717.1 - 8.6e-24 84.6 8.3 8.6e-24 84.6 8.3 2.3 3 1 0 3 3 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA_5 PF07728.14 KFQ92717.1 - 4.2e-09 36.5 0.0 1.4e-08 34.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFQ92717.1 - 2.6e-08 34.2 0.0 9.6e-08 32.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KFQ92717.1 - 4.7e-07 30.4 2.3 1.1e-05 25.9 0.0 3.3 3 1 1 4 4 3 1 AAA ATPase domain RuvB_N PF05496.12 KFQ92717.1 - 6.4e-07 29.2 0.0 1.4e-05 24.9 0.0 2.6 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_PrkA PF08298.11 KFQ92717.1 - 3.1e-06 26.3 0.0 6.2e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 KFQ92717.1 - 3.5e-05 24.1 1.8 0.0011 19.3 0.0 3.6 3 1 0 3 3 2 1 AAA domain AAA_14 PF13173.6 KFQ92717.1 - 0.00051 20.1 0.3 0.0031 17.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFQ92717.1 - 0.0015 18.9 0.0 0.0039 17.6 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Acetate_kinase PF00871.17 KFQ92717.1 - 0.0018 17.1 0.8 0.0028 16.4 0.8 1.3 1 0 0 1 1 1 1 Acetokinase family IstB_IS21 PF01695.17 KFQ92717.1 - 0.0018 18.0 0.0 0.005 16.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein LXG PF04740.12 KFQ92717.1 - 0.013 15.2 1.8 0.14 11.8 0.3 2.9 3 0 0 3 3 3 0 LXG domain of WXG superfamily RsgA_GTPase PF03193.16 KFQ92717.1 - 0.02 14.8 0.2 0.068 13.1 0.0 2.0 2 0 0 2 2 1 0 RsgA GTPase NB-ARC PF00931.22 KFQ92717.1 - 0.021 14.0 0.7 0.078 12.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_3 PF07726.11 KFQ92717.1 - 0.021 14.7 0.0 0.24 11.3 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KFQ92717.1 - 0.022 14.5 0.4 0.071 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KFQ92717.1 - 0.022 14.7 0.0 0.1 12.5 0.0 2.3 1 1 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KFQ92717.1 - 0.026 15.1 0.0 0.026 15.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 KFQ92717.1 - 0.032 14.2 0.3 0.4 10.6 0.0 2.7 2 1 1 3 3 2 0 NTPase TsaE PF02367.17 KFQ92717.1 - 0.035 14.1 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KFQ92717.1 - 0.036 14.2 0.1 0.2 11.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFQ92717.1 - 0.043 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 KFQ92717.1 - 0.059 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFQ92717.1 - 0.062 13.8 0.7 0.57 10.7 0.0 2.7 2 1 0 2 2 2 0 ABC transporter Parvo_NS1 PF01057.17 KFQ92717.1 - 0.075 12.1 0.0 0.22 10.6 0.0 1.8 2 0 0 2 2 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.6 KFQ92717.1 - 0.12 12.9 0.0 0.12 12.9 0.0 3.3 2 2 0 2 2 1 0 AAA domain Viral_helicase1 PF01443.18 KFQ92717.1 - 0.15 11.7 0.0 0.51 10.0 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 KFQ92717.1 - 0.2 11.6 10.6 0.62 9.9 0.0 3.8 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea CbiA PF01656.23 KFQ92717.1 - 0.5 10.4 1.5 1.9 8.5 0.0 2.7 4 1 0 4 4 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.6 KFQ92717.1 - 0.76 10.2 0.0 0.76 10.2 0.0 3.7 3 1 0 3 3 3 0 AAA domain AAA_11 PF13086.6 KFQ92717.1 - 1.1 9.0 0.0 1.1 9.0 0.0 2.9 2 1 0 2 2 1 0 AAA domain Lon_C PF05362.13 KFQ92718.1 - 1.1e-40 139.4 0.0 1.3e-40 139.2 0.0 1.0 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.6 KFQ92718.1 - 4.5e-08 33.0 0.0 5.5e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Ribosomal_L36e PF01158.18 KFQ92719.1 - 2.5e-37 127.0 6.3 2.8e-37 126.8 6.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Filament PF00038.21 KFQ92720.1 - 4.7e-85 285.9 47.2 6.2e-85 285.5 47.2 1.2 1 0 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 KFQ92720.1 - 6.6e-18 65.1 0.4 1.4e-17 64.0 0.4 1.6 1 0 0 1 1 1 1 Lamin Tail Domain BRE1 PF08647.11 KFQ92720.1 - 0.00051 20.1 8.5 0.00051 20.1 8.5 3.9 1 1 3 4 4 3 2 BRE1 E3 ubiquitin ligase Laminin_II PF06009.12 KFQ92720.1 - 0.14 12.2 17.8 0.45 10.5 2.7 3.1 2 1 1 3 3 3 0 Laminin Domain II FPP PF05911.11 KFQ92720.1 - 0.17 10.1 43.5 0.044 12.0 22.0 3.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF1844 PF08899.11 KFQ92720.1 - 0.22 11.8 9.3 0.45 10.8 0.7 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1844) Spc7 PF08317.11 KFQ92720.1 - 0.27 10.1 46.2 0.24 10.2 12.5 2.8 1 1 1 2 2 2 0 Spc7 kinetochore protein FlaC_arch PF05377.11 KFQ92720.1 - 0.28 11.6 9.1 18 5.8 0.4 4.8 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF1326 PF07040.11 KFQ92720.1 - 0.4 10.7 2.2 0.44 10.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1326) DUF1664 PF07889.12 KFQ92720.1 - 0.5 10.4 25.2 7.7 6.6 2.4 5.1 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 KFQ92720.1 - 3.4 7.7 55.7 3 7.9 16.5 5.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein HALZ PF02183.18 KFQ92720.1 - 4.9 7.5 13.8 0.61 10.3 0.7 3.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper Peptidase_A22B PF04258.13 KFQ92721.1 - 3.3e-85 286.1 15.2 4.5e-85 285.6 15.2 1.1 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.22 KFQ92721.1 - 2.9e-08 33.6 0.0 6e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 PA domain DUF4079 PF13301.6 KFQ92721.1 - 0.059 13.5 1.8 0.094 12.9 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) LSM PF01423.22 KFQ92722.1 - 2.3e-21 75.3 0.0 2.7e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain Kelch_6 PF13964.6 KFQ92723.1 - 2e-22 78.6 15.2 7e-06 26.1 0.1 6.5 4 2 2 6 6 6 5 Kelch motif BACK PF07707.15 KFQ92723.1 - 9.6e-21 73.8 2.0 1.8e-20 72.9 0.4 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_1 PF01344.25 KFQ92723.1 - 1.9e-20 72.2 18.0 0.0016 18.0 0.0 7.0 6 1 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KFQ92723.1 - 9.5e-08 32.1 6.9 0.042 14.2 0.1 5.2 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_4 PF13418.6 KFQ92723.1 - 9.8e-08 31.9 11.4 0.076 13.0 0.1 6.2 5 2 2 7 7 7 2 Galactose oxidase, central domain Kelch_2 PF07646.15 KFQ92723.1 - 2.6e-07 30.3 8.1 0.28 11.2 0.1 5.7 5 1 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 KFQ92723.1 - 2.8e-07 30.4 5.8 0.16 12.0 0.1 5.7 6 0 0 6 6 6 3 Kelch motif BTB PF00651.31 KFQ92723.1 - 3e-06 27.4 0.1 4.8e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain TRAM_LAG1_CLN8 PF03798.16 KFQ92724.1 - 1.2e-42 145.9 27.0 1.6e-42 145.5 27.0 1.2 1 0 0 1 1 1 1 TLC domain Homeodomain PF00046.29 KFQ92724.1 - 9.5e-07 28.6 0.5 4.4e-06 26.4 0.3 2.0 2 0 0 2 2 2 1 Homeodomain Lipoxygenase PF00305.19 KFQ92726.1 - 2.2e-72 244.6 0.0 7.3e-72 242.8 0.0 1.7 1 1 0 1 1 1 1 Lipoxygenase PLAT PF01477.23 KFQ92726.1 - 1e-19 71.2 0.0 1.7e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 PLAT/LH2 domain CCD48 PF15799.5 KFQ92727.1 - 9.8e-51 172.8 10.9 1.1e-50 172.6 10.9 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 LRRNT PF01462.18 KFQ92728.1 - 4.5e-09 35.7 9.2 1.1e-08 34.5 3.9 3.1 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_8 PF13855.6 KFQ92728.1 - 1.9e-05 24.3 0.0 4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KFQ92728.1 - 4.9e-05 23.6 0.1 0.0006 20.2 0.1 2.5 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRRCT PF01463.24 KFQ92728.1 - 0.0013 19.1 0.1 0.0051 17.3 0.0 2.1 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain LRR_1 PF00560.33 KFQ92728.1 - 0.045 14.3 0.6 0.37 11.5 0.1 2.8 2 0 0 2 2 2 0 Leucine Rich Repeat Ras PF00071.22 KFQ92729.1 - 4.1e-36 124.0 0.1 5e-36 123.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ92729.1 - 9.4e-18 64.6 0.0 2e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ92729.1 - 1.6e-06 27.7 0.1 1.9e-06 27.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Hydrolase_6 PF13344.6 KFQ92730.1 - 1.9e-22 79.3 0.0 3.8e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFQ92730.1 - 0.00015 21.8 0.1 0.006 16.6 0.1 2.9 1 1 0 1 1 1 1 HAD-hyrolase-like Isy1 PF06246.12 KFQ92731.1 - 9.2e-68 228.6 6.8 1.1e-67 228.3 6.8 1.0 1 0 0 1 1 1 1 Isy1-like splicing family BCAS3 PF12490.8 KFQ92731.1 - 0.039 13.5 0.7 0.049 13.1 0.7 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 zf-CCHC PF00098.23 KFQ92732.1 - 4.7e-53 175.0 63.9 3.3e-08 33.3 2.1 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_5 PF14787.6 KFQ92732.1 - 3.8e-16 58.5 47.7 0.0004 20.0 1.7 7.1 5 1 2 7 7 7 6 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 KFQ92732.1 - 7e-13 48.1 46.8 0.02 14.6 0.6 7.1 6 1 1 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 KFQ92732.1 - 1.7e-08 34.2 48.6 0.0024 17.8 0.3 7.0 2 1 5 7 7 7 6 Zinc knuckle zf-CCHC_2 PF13696.6 KFQ92732.1 - 0.0003 20.5 58.1 0.0037 17.0 1.4 7.2 7 0 0 7 7 7 5 Zinc knuckle Pkinase_Tyr PF07714.17 KFQ92733.1 - 6.2e-63 212.5 0.0 8.3e-63 212.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ92733.1 - 4.1e-61 206.7 0.0 5.5e-61 206.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RBD PF02196.15 KFQ92733.1 - 3.6e-28 97.4 0.1 8e-28 96.3 0.1 1.6 1 0 0 1 1 1 1 Raf-like Ras-binding domain C1_1 PF00130.22 KFQ92733.1 - 2.9e-12 46.3 8.5 5.7e-12 45.3 8.5 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 KFQ92733.1 - 4.6e-07 29.4 0.0 8e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFQ92733.1 - 9.5e-05 21.3 0.1 0.00017 20.5 0.1 1.5 1 1 0 1 1 1 1 Fungal protein kinase zf-RING-like PF08746.11 KFQ92733.1 - 0.00023 21.4 4.4 0.00078 19.7 4.4 1.9 1 0 0 1 1 1 1 RING-like domain C1_2 PF03107.16 KFQ92733.1 - 0.035 14.4 4.0 0.073 13.4 4.0 1.5 1 0 0 1 1 1 0 C1 domain Zf_RING PF16744.5 KFQ92733.1 - 0.52 10.5 3.6 2.1 8.5 3.6 2.0 1 0 0 1 1 1 0 KIAA1045 RING finger zf-C3HC4_2 PF13923.6 KFQ92733.1 - 0.93 9.4 10.1 0.19 11.6 5.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ92733.1 - 5.6 7.4 12.5 0.46 10.9 7.2 2.0 2 0 0 2 2 2 0 Ring finger domain zf-CCCH_4 PF18044.1 KFQ92734.1 - 6.3e-24 83.3 32.3 1.5e-07 31.0 3.3 5.0 5 0 0 5 5 5 4 CCCH-type zinc finger zf-CCCH PF00642.24 KFQ92734.1 - 7.9e-21 73.5 28.1 1.6e-06 27.8 3.3 4.6 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFQ92734.1 - 1.4e-20 72.6 33.6 9e-06 25.6 8.3 5.4 4 1 0 4 4 4 4 Zinc finger domain Torus PF16131.5 KFQ92734.1 - 9.2e-14 52.1 16.2 0.00044 20.9 1.1 4.5 3 1 1 4 4 4 4 Torus domain zf-CCCH_2 PF14608.6 KFQ92734.1 - 2e-07 31.2 22.0 0.048 14.1 1.6 5.1 4 1 0 4 4 4 4 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KFQ92734.1 - 4.2e-05 23.7 2.7 4.2e-05 23.7 2.7 3.1 3 0 0 3 3 3 1 Zinc-finger containing family zf-C3HC4 PF00097.25 KFQ92734.1 - 8.8e-05 22.3 10.6 8.8e-05 22.3 10.6 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFQ92734.1 - 0.00036 20.5 6.4 0.00036 20.5 6.4 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFQ92734.1 - 0.00068 19.9 10.2 0.00068 19.9 10.2 3.7 4 1 1 5 5 4 1 Ring finger domain zf-RING_5 PF14634.6 KFQ92734.1 - 0.00097 19.0 9.1 0.00097 19.0 9.1 3.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFQ92734.1 - 0.0076 16.4 10.1 0.011 15.9 6.5 3.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING MKRN1_C PF15815.5 KFQ92734.1 - 0.055 13.9 0.2 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase makorin-1, C-terminal APOBEC1 PF18769.1 KFQ92734.1 - 0.11 12.8 0.4 0.25 11.6 0.4 1.6 1 0 0 1 1 1 0 APOBEC1 zf-C3HC4_2 PF13923.6 KFQ92734.1 - 1 9.2 17.7 0.5 10.2 10.8 3.9 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) tRNA_int_endo_N PF02778.14 KFQ92735.1 - 1.8e-20 72.4 0.5 3.1e-14 52.4 0.5 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain tRNA_int_endo PF01974.17 KFQ92735.1 - 4.9e-17 61.8 0.0 1e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain PPARgamma_N PF12577.8 KFQ92736.1 - 6.9e-35 119.6 1.6 1.7e-34 118.3 1.6 1.7 1 0 0 1 1 1 1 PPAR gamma N-terminal region zf-C4 PF00105.18 KFQ92736.1 - 1.5e-27 95.8 15.0 2.9e-27 94.9 15.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFQ92736.1 - 5.1e-17 62.1 0.4 1.4e-16 60.7 0.4 1.8 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Tmemb_55A PF09788.9 KFQ92736.1 - 0.02 14.0 3.8 0.033 13.3 3.8 1.3 1 0 0 1 1 1 0 Transmembrane protein 55A Synapsin_C PF02750.14 KFQ92737.1 - 8.8e-135 446.6 0.9 1.1e-134 446.4 0.9 1.1 1 0 0 1 1 1 1 Synapsin, ATP binding domain Synapsin PF02078.16 KFQ92737.1 - 1.6e-11 44.3 0.1 9.3e-11 41.9 0.0 2.1 2 0 0 2 2 2 1 Synapsin, N-terminal domain TIMP PF00965.17 KFQ92738.1 - 2.1e-58 197.1 4.1 2.3e-58 197.0 4.1 1.0 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.21 KFQ92738.1 - 0.034 14.0 0.1 0.05 13.4 0.1 1.3 1 0 0 1 1 1 0 UNC-6/NTR/C345C module Tam41_Mmp37 PF09139.11 KFQ92739.1 - 4.6e-87 292.5 0.0 5e-87 292.3 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial VGLL4 PF15245.6 KFQ92740.1 - 1.2e-105 352.4 3.4 9.7e-105 349.4 5.2 1.6 2 0 0 2 2 2 1 Transcription cofactor vestigial-like protein 4 Vg_Tdu PF07545.14 KFQ92740.1 - 6.2e-05 22.7 0.0 0.25 11.1 0.0 2.5 2 0 0 2 2 2 2 Vestigial/Tondu family DUF3868 PF12984.7 KFQ92740.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3868) ATG7_N PF16420.5 KFQ92741.1 - 1.4e-91 307.3 0.0 1.9e-91 306.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KFQ92741.1 - 1.9e-56 191.1 0.0 3e-56 190.5 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 KFQ92741.1 - 0.04 14.0 0.0 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Maf PF02545.14 KFQ92741.1 - 0.054 13.3 0.0 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Maf-like protein 7tm_1 PF00001.21 KFQ92742.1 - 1.1e-70 238.0 0.4 1.4e-70 237.7 0.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ92742.1 - 1.1e-09 38.1 12.1 9.8e-07 28.4 5.9 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFQ92742.1 - 2e-07 31.1 13.5 2.8e-06 27.3 8.3 2.7 2 1 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFQ92742.1 - 7.3e-05 22.5 10.9 7.3e-05 22.5 10.9 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx CoA_binding_3 PF13727.6 KFQ92742.1 - 0.0094 16.0 0.8 0.21 11.6 0.2 2.4 2 0 0 2 2 2 1 CoA-binding domain Serpentine_r_xa PF03383.15 KFQ92742.1 - 0.012 15.6 0.8 0.038 13.9 0.8 1.8 1 0 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa MAR_sialic_bdg PF10564.9 KFQ92742.1 - 0.016 15.2 0.5 0.038 14.0 0.5 1.6 1 0 0 1 1 1 0 Sialic-acid binding micronemal adhesive repeat S_4TM PF18159.1 KFQ92742.1 - 0.28 10.5 0.0 0.28 10.5 0.0 2.1 3 0 0 3 3 3 0 SMODS-associating 4TM effector domain SNF PF00209.18 KFQ92743.1 - 7.6e-234 777.2 41.4 8.7e-234 777.0 41.4 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 KFQ92745.1 - 9.7e-248 823.1 38.8 1.1e-247 822.9 38.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Cation_ATPase_C PF00689.21 KFQ92747.1 - 9.1e-45 152.6 5.4 1.9e-44 151.5 2.6 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KFQ92747.1 - 8.2e-34 116.7 14.4 2.9e-25 88.8 1.5 2.9 3 0 0 3 3 3 2 E1-E2 ATPase ATP_Ca_trans_C PF12424.8 KFQ92747.1 - 6.7e-27 93.7 0.1 1.9e-26 92.3 0.1 1.9 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal Cation_ATPase PF13246.6 KFQ92747.1 - 7e-18 64.5 0.0 1.5e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFQ92747.1 - 2.1e-15 57.6 0.0 3.1e-11 44.0 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFQ92747.1 - 2.8e-15 55.7 0.0 1.5e-14 53.4 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFQ92747.1 - 2.1e-09 37.5 0.6 7.1e-06 26.0 0.2 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase tRNA-synt_1 PF00133.22 KFQ92748.1 - 3.5e-241 801.7 0.0 1.9e-240 799.3 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KFQ92748.1 - 2.5e-25 89.2 0.2 9.4e-25 87.3 0.1 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KFQ92748.1 - 9.1e-14 51.0 0.3 0.0008 18.3 0.0 4.1 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KFQ92748.1 - 0.016 14.6 0.0 0.06 12.7 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain zf-HC5HC2H PF13771.6 KFQ92749.1 - 6.8e-15 55.1 0.3 6.8e-15 55.1 0.3 1.6 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFQ92749.1 - 4.6e-10 39.6 5.9 7.5e-10 38.9 5.9 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain C1_2 PF03107.16 KFQ92749.1 - 0.016 15.5 0.6 0.016 15.5 0.6 2.0 2 1 0 2 2 2 0 C1 domain PHD PF00628.29 KFQ92749.1 - 0.035 14.0 3.8 0.035 14.0 3.8 2.6 2 1 0 2 2 2 0 PHD-finger ADK_lid PF05191.14 KFQ92749.1 - 0.69 9.9 4.5 18 5.4 0.3 3.2 3 0 0 3 3 3 0 Adenylate kinase, active site lid Cyclotide PF03784.13 KFQ92749.1 - 8.8 6.5 11.7 1.1 9.4 5.3 2.5 2 1 0 2 2 2 0 Cyclotide family Shisa PF13908.6 KFQ92750.1 - 1.5e-19 71.0 10.8 1.5e-19 71.0 10.8 1.9 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator Corona_S2 PF01601.16 KFQ92750.1 - 4.5 5.6 6.3 5.4 5.4 6.3 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein BTG PF07742.12 KFQ92751.1 - 4.2e-28 97.5 0.0 6.5e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 BTG family Ins_P5_2-kin PF06090.12 KFQ92752.1 - 1e-90 304.6 0.3 1.1e-90 304.4 0.3 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase zf-C3HC4 PF00097.25 KFQ92752.1 - 0.15 11.9 1.7 0.61 10.0 1.7 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RVT_1 PF00078.27 KFQ92754.1 - 0.003 17.1 0.0 0.0065 16.0 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_8 PF13855.6 KFQ92755.1 - 3.7e-51 170.7 23.8 1.6e-16 59.8 0.1 6.6 5 2 1 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFQ92755.1 - 8e-30 102.4 28.9 1.9e-05 24.9 1.2 8.5 6 1 3 9 9 9 8 Leucine Rich repeats (2 copies) VWC PF00093.18 KFQ92755.1 - 1.2e-11 44.7 13.0 2.8e-11 43.5 13.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type C domain LRR_1 PF00560.33 KFQ92755.1 - 1.1e-10 40.5 27.9 7.4 7.5 0.0 11.9 11 1 0 11 11 11 3 Leucine Rich Repeat LRR_5 PF13306.6 KFQ92755.1 - 2e-10 40.7 0.3 4.1e-05 23.5 0.0 3.4 2 1 2 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFQ92755.1 - 5e-08 32.6 16.0 6.4e-05 22.5 0.8 5.3 2 1 3 5 5 5 3 Leucine-rich repeat LRR_6 PF13516.6 KFQ92755.1 - 1.7e-05 24.5 24.7 0.4 10.9 0.0 9.7 11 0 0 11 11 11 2 Leucine Rich repeat Amnionless PF14828.6 KFQ92755.1 - 2e-05 23.7 2.3 3.2e-05 22.9 2.3 1.3 1 0 0 1 1 1 1 Amnionless LRRNT PF01462.18 KFQ92755.1 - 0.022 14.4 6.8 0.24 11.1 0.2 3.9 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain FNIP PF05725.12 KFQ92755.1 - 0.062 13.5 11.3 5.1 7.3 0.3 4.3 4 0 0 4 4 4 0 FNIP Repeat Peptidase_S49_N PF08496.10 KFQ92755.1 - 9.9 6.2 6.5 20 5.2 6.5 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal LRR_8 PF13855.6 KFQ92757.1 - 1.7e-19 69.3 2.8 1.3e-07 31.3 0.0 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFQ92757.1 - 7.2e-13 48.5 8.5 0.00015 22.1 0.2 4.1 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFQ92757.1 - 3.6e-06 26.9 0.5 0.022 14.7 0.0 2.4 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFQ92757.1 - 1.3e-05 25.1 5.1 4.5 8.2 0.1 5.9 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 KFQ92757.1 - 0.00096 19.0 2.7 2.7 8.3 0.0 4.7 5 0 0 5 5 5 1 Leucine Rich repeat LRR_9 PF14580.6 KFQ92757.1 - 0.053 13.0 2.5 0.92 9.0 0.2 2.2 1 1 1 2 2 2 0 Leucine-rich repeat CENP-P PF13096.6 KFQ92758.1 - 2.5e-37 128.3 1.7 2.5e-37 128.3 1.7 1.5 2 0 0 2 2 2 1 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P DUF1474 PF07342.11 KFQ92758.1 - 0.035 14.6 3.8 0.48 11.0 0.2 2.6 1 1 1 3 3 3 0 Protein of unknown function (DUF1474) TMF_TATA_bd PF12325.8 KFQ92758.1 - 0.3 11.3 5.8 0.077 13.2 1.0 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding RRM_1 PF00076.22 KFQ92759.1 - 6e-06 26.0 0.0 1.6e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFQ92759.1 - 0.14 12.3 0.0 0.42 10.8 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif TBCA PF02970.16 KFQ92760.1 - 1.2e-11 44.7 2.0 1.5e-11 44.4 2.0 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A zf-RVT PF13966.6 KFQ92761.1 - 0.0049 17.5 0.3 0.01 16.6 0.3 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase AHJR-like PF18743.1 KFQ92761.1 - 0.014 14.9 0.2 0.023 14.3 0.2 1.3 1 0 0 1 1 1 0 REase_AHJR-like L_protein_N PF15518.6 KFQ92761.1 - 0.039 13.8 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 L protein N-terminus FolB PF02152.18 KFQ92761.1 - 0.16 12.5 1.1 0.24 11.9 0.3 1.6 2 0 0 2 2 2 0 Dihydroneopterin aldolase PTR2 PF00854.21 KFQ92763.1 - 1.7e-52 178.6 0.5 2.3e-52 178.2 0.5 1.1 1 0 0 1 1 1 1 POT family MFS_2 PF13347.6 KFQ92763.1 - 1.7e-07 30.2 4.4 6.8e-06 24.9 3.3 1.8 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 KFQ92763.1 - 5.6e-07 28.8 1.8 1e-06 28.0 1.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DHR-2 PF06920.13 KFQ92764.1 - 8.9e-211 701.1 7.2 8.9e-211 701.1 7.2 2.1 2 0 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 KFQ92764.1 - 3.8e-58 196.5 0.4 1.1e-57 195.0 0.4 1.9 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 KFQ92764.1 - 3.8e-42 143.3 0.7 1.3e-41 141.6 0.7 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) PH PF00169.29 KFQ92764.1 - 4.2e-14 52.9 0.3 1.5e-13 51.2 0.3 2.1 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KFQ92764.1 - 3.3e-05 24.2 0.0 0.00018 21.8 0.0 2.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KFQ92764.1 - 0.028 14.7 0.1 0.081 13.2 0.1 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain UBA PF00627.31 KFQ92765.1 - 4.3e-12 45.7 0.6 7.4e-12 44.9 0.6 1.4 1 0 0 1 1 1 1 UBA/TS-N domain 7tm_1 PF00001.21 KFQ92766.1 - 3.5e-34 118.3 23.1 4.8e-34 117.9 23.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFQ92766.1 - 0.00052 19.7 30.3 0.00091 18.9 29.5 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 KFQ92767.1 - 5.5e-50 170.1 17.4 7.9e-50 169.6 17.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Srg PF02118.21 KFQ92767.1 - 0.0039 16.9 21.7 0.0039 16.9 21.7 1.6 1 1 0 1 1 1 1 Srg family chemoreceptor 7TM_GPCR_Srd PF10317.9 KFQ92767.1 - 1.8 7.7 32.8 20 4.2 32.8 2.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd 7tm_1 PF00001.21 KFQ92768.1 - 6e-49 166.7 14.3 7.4e-49 166.4 14.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) OapA_N PF08525.11 KFQ92768.1 - 0.24 11.4 3.4 0.85 9.6 3.4 1.9 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif Chordopox_G3 PF06129.12 KFQ92768.1 - 2.9 8.6 5.6 0.55 11.0 1.1 2.2 3 0 0 3 3 3 0 Chordopoxvirus G3 protein HpcH_HpaI PF03328.14 KFQ92769.1 - 1.6e-48 164.8 0.0 2e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KFQ92769.1 - 3.8e-11 42.7 0.1 7.7e-07 28.6 0.0 2.2 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PUFD PF16553.5 KFQ92770.1 - 1.5e-40 137.9 0.3 3e-40 136.9 0.3 1.5 1 0 0 1 1 1 1 BCORL-PCGF1-binding domain Ank_4 PF13637.6 KFQ92770.1 - 9.4e-13 48.4 4.6 6.8e-07 29.7 0.3 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFQ92770.1 - 1e-12 48.4 0.9 5e-11 43.0 0.8 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFQ92770.1 - 1.1e-10 40.8 0.4 2.8e-05 24.2 0.3 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KFQ92770.1 - 3.1e-08 33.7 1.0 8e-05 22.9 0.2 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KFQ92770.1 - 1.2e-07 31.9 2.7 4.6e-05 23.6 0.2 3.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Hormone_recep PF00104.30 KFQ92771.1 - 8.1e-13 48.4 0.0 1.5e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor LIFR_D2 PF17971.1 KFQ92772.1 - 2.6e-19 69.5 4.9 2.6e-19 69.5 4.9 2.5 2 0 0 2 2 2 1 Leukemia inhibitory factor receptor D2 domain fn3 PF00041.21 KFQ92772.1 - 9.1e-17 61.2 6.2 2.1e-05 24.8 0.1 5.8 6 0 0 6 6 6 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFQ92772.1 - 0.15 12.7 0.0 0.15 12.7 0.0 3.4 4 0 0 4 4 4 0 Purple acid Phosphatase, N-terminal domain PKD PF00801.20 KFQ92772.1 - 0.67 9.8 2.7 7.3 6.5 0.1 3.9 3 2 1 4 4 4 0 PKD domain Yae1_N PF09811.9 KFQ92773.1 - 4.5e-09 35.9 30.0 0.0042 16.8 7.4 3.2 1 1 1 2 2 2 2 Essential protein Yae1, N terminal Nucleoporin_N PF08801.11 KFQ92774.1 - 6.9e-109 364.5 0.0 9.3e-109 364.0 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KFQ92774.1 - 2.1e-21 76.3 7.2 3.1e-21 75.8 7.2 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal JAB PF01398.21 KFQ92775.1 - 3.3e-20 72.2 0.0 3.3e-20 72.2 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KFQ92775.1 - 1.3e-07 31.4 0.4 9.4e-07 28.6 0.0 2.1 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain Peptidase_S8 PF00082.22 KFQ92776.1 - 1.8e-14 53.8 0.2 1.8e-14 53.7 0.2 1.0 1 0 0 1 1 1 1 Subtilase family Rad17 PF03215.15 KFQ92778.1 - 3.4e-61 206.4 0.1 3.4e-61 206.4 0.1 1.6 2 0 0 2 2 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KFQ92778.1 - 1.8e-06 28.5 0.0 4.7e-06 27.1 0.0 1.6 2 0 0 2 2 1 1 AAA ATPase domain RuvB_N PF05496.12 KFQ92778.1 - 1.3e-05 25.0 0.0 2.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 KFQ92778.1 - 1.6e-05 25.3 0.0 3.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KFQ92778.1 - 0.00011 22.7 0.0 0.0013 19.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFQ92778.1 - 0.0019 18.5 0.0 0.0056 17.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFQ92778.1 - 0.0036 17.3 0.0 0.0076 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_assoc_2 PF16193.5 KFQ92778.1 - 0.0043 17.4 0.0 0.013 15.8 0.0 1.9 2 0 0 2 2 1 1 AAA C-terminal domain RNA_helicase PF00910.22 KFQ92778.1 - 0.0064 16.9 0.0 0.024 15.0 0.0 2.0 1 1 0 1 1 1 1 RNA helicase AAA_19 PF13245.6 KFQ92778.1 - 0.0074 16.6 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KFQ92778.1 - 0.0097 15.4 0.0 0.026 14.1 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region TsaE PF02367.17 KFQ92778.1 - 0.016 15.2 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 KFQ92778.1 - 0.023 14.5 0.3 0.072 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 KFQ92778.1 - 0.027 13.7 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Zeta_toxin PF06414.12 KFQ92778.1 - 0.049 12.9 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DMA PF03474.14 KFQ92778.1 - 0.057 13.0 0.0 0.28 10.8 0.0 2.2 2 0 0 2 2 2 0 DMRTA motif AAA_28 PF13521.6 KFQ92778.1 - 0.068 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFQ92778.1 - 0.077 13.5 0.0 0.21 12.1 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 KFQ92778.1 - 0.097 12.7 0.0 0.2 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KFQ92778.1 - 0.11 12.4 0.0 0.34 10.8 0.0 1.8 1 0 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.18 KFQ92778.1 - 0.13 12.0 0.0 0.4 10.4 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KFQ92778.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KFQ92778.1 - 0.18 11.4 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFQ92779.1 - 3.2e-27 95.6 0.1 8.2e-27 94.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KFQ92779.1 - 9.2e-07 29.4 0.2 2.1e-06 28.2 0.1 1.7 1 1 1 2 2 2 1 AAA domain SKI PF01202.22 KFQ92779.1 - 0.00021 21.4 1.7 0.009 16.1 0.1 2.6 2 1 1 3 3 3 1 Shikimate kinase AAA PF00004.29 KFQ92779.1 - 0.00068 20.1 0.0 0.0015 19.0 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KFQ92779.1 - 0.0029 17.9 0.0 0.0049 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFQ92779.1 - 0.012 15.8 0.1 0.016 15.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFQ92779.1 - 0.02 15.2 0.0 0.18 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain ADK PF00406.22 KFQ92779.1 - 0.021 15.0 0.2 0.076 13.1 0.1 1.8 2 0 0 2 2 2 0 Adenylate kinase Cytidylate_kin PF02224.18 KFQ92779.1 - 0.058 13.1 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase Cytidylate_kin2 PF13189.6 KFQ92779.1 - 0.088 12.9 0.0 0.12 12.5 0.0 1.5 1 1 0 1 1 1 0 Cytidylate kinase-like family DUF2353 PF09789.9 KFQ92780.1 - 0.014 14.8 0.6 0.014 14.8 0.6 4.1 1 1 2 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) FapA PF03961.13 KFQ92780.1 - 8.5 4.9 18.6 0.25 9.9 11.0 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF3480 PF11979.8 KFQ92781.1 - 6.7e-32 110.8 0.3 1.6e-31 109.6 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3480) FYVE PF01363.21 KFQ92781.1 - 1.6e-18 66.6 14.6 4.3e-18 65.2 14.6 1.8 1 0 0 1 1 1 1 FYVE zinc finger SARA PF11409.8 KFQ92781.1 - 0.0076 16.4 5.4 0.02 15.1 5.4 1.8 1 0 0 1 1 1 1 Smad anchor for receptor activation (SARA) DUF3480 PF11979.8 KFQ92782.1 - 1.4e-107 359.7 0.0 1.6e-107 359.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3480) DUF2181 PF10223.9 KFQ92783.1 - 2.4e-85 285.9 0.2 2.7e-85 285.7 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2181) MACPF PF01823.19 KFQ92783.1 - 0.049 13.7 0.1 0.079 13.0 0.1 1.2 1 0 0 1 1 1 0 MAC/Perforin domain Ank_2 PF12796.7 KFQ92784.1 - 5.4e-26 91.0 0.2 9.4e-15 55.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ92784.1 - 9.5e-21 73.9 0.0 7e-07 29.7 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFQ92784.1 - 1.2e-15 57.1 0.0 5.7e-06 26.5 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KFQ92784.1 - 2.5e-12 45.8 0.0 0.00014 22.0 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KFQ92784.1 - 4.9e-12 45.8 0.2 5.3e-06 26.6 0.0 3.4 4 1 1 5 5 5 3 Ankyrin repeats (many copies) DHFR_1 PF00186.19 KFQ92785.1 - 2e-26 92.6 0.0 2.2e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrofolate reductase MutS_V PF00488.21 KFQ92786.1 - 2.3e-73 246.3 0.3 5e-73 245.2 0.3 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFQ92786.1 - 1.2e-35 123.4 1.5 2.4e-35 122.5 0.6 1.9 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 KFQ92786.1 - 6.4e-11 42.7 0.1 1.9e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KFQ92786.1 - 0.00025 21.3 0.1 0.00075 19.8 0.1 1.8 1 0 0 1 1 1 1 MutS family domain IV AXE1 PF05448.12 KFQ92786.1 - 0.087 11.5 0.0 0.19 10.3 0.0 1.5 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) ATP-gua_Ptrans PF00217.19 KFQ92788.1 - 2.7e-81 272.1 0.0 3.4e-81 271.8 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 KFQ92788.1 - 3e-31 107.6 0.0 5.2e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain zf-CCHC PF00098.23 KFQ92789.1 - 7.6e-17 60.5 25.8 3.3e-06 26.9 0.6 4.4 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.6 KFQ92789.1 - 5.8e-07 29.2 27.2 0.00046 19.9 0.5 4.7 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_4 PF14392.6 KFQ92789.1 - 0.02 14.6 21.9 0.55 10.0 0.6 4.4 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_5 PF14787.6 KFQ92789.1 - 0.042 13.5 0.2 0.042 13.5 0.2 3.7 4 0 0 4 4 4 0 GAG-polyprotein viral zinc-finger Prim_Zn_Ribbon PF08273.12 KFQ92789.1 - 0.22 11.8 7.5 2.7 8.4 0.1 3.5 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase zf-C2H2_10 PF16588.5 KFQ92789.1 - 0.26 11.0 0.0 0.26 11.0 0.0 3.0 4 0 0 4 4 4 0 C2H2 zinc-finger zf-CCCH_6 PF18585.1 KFQ92789.1 - 0.76 9.7 0.0 0.76 9.7 0.0 2.9 3 0 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 PHD_4 PF16866.5 KFQ92789.1 - 4.7 7.4 12.0 1.9 8.6 1.4 3.1 1 1 2 3 3 3 0 PHD-finger START PF01852.19 KFQ92790.1 - 7.7e-20 71.2 0.1 8.9e-20 71.0 0.1 1.1 1 0 0 1 1 1 1 START domain 4HBT PF03061.22 KFQ92791.1 - 1e-18 67.4 0.9 4.4e-10 39.8 0.1 2.2 2 0 0 2 2 2 2 Thioesterase superfamily PTSIIB_sorb PF03830.15 KFQ92791.1 - 0.021 15.1 0.1 0.36 11.1 0.0 2.3 2 0 0 2 2 2 0 PTS system sorbose subfamily IIB component SSDP PF04503.13 KFQ92792.1 - 1.3e-74 252.1 75.8 2.3e-59 202.1 64.2 2.0 1 1 1 2 2 2 2 Single-stranded DNA binding protein, SSDP Autophagy_act_C PF03987.15 KFQ92793.1 - 7.6e-20 71.3 0.9 1.3e-19 70.5 0.9 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Ribosom_S12_S23 PF00164.25 KFQ92794.1 - 3.6e-43 145.8 0.6 3.9e-43 145.7 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 ATP-synt_S1 PF05827.12 KFQ92795.1 - 1.9e-47 160.8 0.7 2.3e-47 160.5 0.7 1.1 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) DUF1242 PF06842.12 KFQ92796.1 - 3e-16 58.9 1.7 3.4e-16 58.7 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) WBP-1 PF11669.8 KFQ92796.1 - 0.031 14.9 0.0 0.031 14.9 0.0 1.0 1 0 0 1 1 1 0 WW domain-binding protein 1 XRCC4 PF06632.12 KFQ92797.1 - 1.5e-120 402.1 0.8 2e-120 401.7 0.8 1.2 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Leu_zip PF15294.6 KFQ92797.1 - 0.00046 19.8 2.8 0.00078 19.0 2.8 1.3 1 0 0 1 1 1 1 Leucine zipper ParD_antitoxin PF03693.14 KFQ92797.1 - 0.026 14.9 0.3 4.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH Prefoldin_2 PF01920.20 KFQ92797.1 - 0.12 12.4 4.8 1.6 8.7 0.4 2.5 2 0 0 2 2 2 0 Prefoldin subunit KxDL PF10241.9 KFQ92797.1 - 0.43 10.9 4.0 0.6 10.4 0.3 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein Pox_A_type_inc PF04508.12 KFQ92797.1 - 0.59 10.1 4.2 14 5.7 0.6 3.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat ZapB PF06005.12 KFQ92797.1 - 1.8 9.1 7.9 19 5.8 8.0 2.4 1 1 1 2 2 2 0 Cell division protein ZapB Xlink PF00193.17 KFQ92798.1 - 1.4e-63 211.3 0.0 3.4e-34 117.1 0.0 2.3 2 0 0 2 2 2 2 Extracellular link domain V-set PF07686.17 KFQ92798.1 - 5.6e-10 39.4 0.0 1.1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFQ92798.1 - 4.6e-05 23.9 0.0 0.00014 22.4 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ92798.1 - 5.8e-05 23.1 0.0 0.00014 21.9 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFQ92798.1 - 0.0004 20.7 0.0 0.0065 16.8 0.0 2.3 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFQ92798.1 - 0.0054 16.9 0.1 0.013 15.6 0.1 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFQ92798.1 - 0.15 12.2 0.0 0.49 10.5 0.0 1.8 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain F5_F8_type_C PF00754.25 KFQ92799.1 - 8.5e-62 206.9 5.6 3.3e-32 111.3 0.8 2.1 2 0 0 2 2 2 2 F5/8 type C domain EGF PF00008.27 KFQ92799.1 - 1.2e-21 76.6 37.2 1.8e-08 34.5 8.5 3.6 3 0 0 3 3 3 3 EGF-like domain hEGF PF12661.7 KFQ92799.1 - 2.4e-09 37.5 38.3 0.00031 21.3 4.4 4.7 4 1 0 4 4 4 3 Human growth factor-like EGF EGF_2 PF07974.13 KFQ92799.1 - 7.6e-05 23.0 39.8 0.082 13.3 7.4 3.7 3 0 0 3 3 3 3 EGF-like domain DUF1438 PF07270.11 KFQ92799.1 - 0.046 13.8 0.1 14 5.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1438) Pepdidase_M14_N PF18027.1 KFQ92799.1 - 0.41 11.0 3.1 2.1 8.8 0.2 2.6 2 1 0 2 2 2 0 Cytosolic carboxypeptidase N-terminal domain AAA_33 PF13671.6 KFQ92800.1 - 2.6e-09 37.4 0.1 3.4e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 AAA domain BRCA-2_helical PF09169.10 KFQ92801.1 - 3.4e-93 310.5 0.2 1.7e-92 308.3 0.0 2.4 2 0 0 2 2 2 1 BRCA2, helical BRCA-2_OB3 PF09104.10 KFQ92801.1 - 3.5e-51 172.5 1.0 8e-51 171.4 0.1 2.2 2 0 0 2 2 2 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 BRCA-2_OB1 PF09103.10 KFQ92801.1 - 6.6e-41 139.1 0.0 2.1e-40 137.5 0.0 2.0 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA2 PF00634.18 KFQ92801.1 - 4e-40 135.1 27.1 3.7e-10 39.3 0.2 7.7 7 1 1 8 8 8 5 BRCA2 repeat Tower PF09121.10 KFQ92801.1 - 7.5e-20 70.9 3.7 2.1e-19 69.4 3.7 1.9 1 0 0 1 1 1 1 Tower Phage_TTP_1 PF04630.12 KFQ92801.1 - 0.014 14.7 1.5 0.055 12.8 0.4 2.2 2 0 0 2 2 2 0 Phage tail tube protein DUF45 PF01863.17 KFQ92801.1 - 1 9.4 5.3 1.6 8.7 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function DUF45 zf-3CxxC PF13695.6 KFQ92802.1 - 3.5e-09 37.0 17.5 6e-09 36.3 17.5 1.4 1 0 0 1 1 1 1 Zinc-binding domain zf-3CxxC_2 PF17180.4 KFQ92802.1 - 0.00045 20.9 23.7 0.00045 20.9 23.7 2.3 2 1 0 2 2 2 1 Zinc-binding domain Fringe PF02434.16 KFQ92803.1 - 5.6e-64 216.0 0.0 8.5e-57 192.5 0.0 2.7 2 1 0 2 2 2 2 Fringe-like Galactosyl_T PF01762.21 KFQ92803.1 - 2.6e-06 27.4 0.0 0.13 12.1 0.0 3.2 2 1 1 3 3 3 3 Galactosyltransferase DUF604 PF04646.12 KFQ92803.1 - 0.0002 20.8 0.4 0.00043 19.8 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF604 Glycos_transf_2 PF00535.26 KFQ92803.1 - 0.025 14.4 0.0 0.068 13.0 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 2 HSP70 PF00012.20 KFQ92805.1 - 7.6e-151 503.3 4.5 6.3e-150 500.2 0.3 2.8 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KFQ92805.1 - 0.084 11.7 0.3 0.23 10.2 0.1 1.7 2 0 0 2 2 2 0 MreB/Mbl protein MAPEG PF01124.18 KFQ92806.1 - 1.8e-08 34.4 0.4 2.2e-08 34.0 0.4 1.2 1 0 0 1 1 1 1 MAPEG family Ndr PF03096.14 KFQ92806.1 - 0.15 10.7 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Ndr family HMG_box PF00505.19 KFQ92808.1 - 3.7e-42 142.6 12.6 2e-27 95.4 0.5 2.8 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KFQ92808.1 - 8.8e-41 138.4 12.7 9.9e-27 93.4 7.4 2.7 3 0 0 3 3 3 2 HMG-box domain HMG_box_5 PF14887.6 KFQ92808.1 - 0.034 14.1 15.9 0.48 10.4 3.9 2.5 2 1 0 2 2 2 0 HMG (high mobility group) box 5 Astro_capsid_p PF12226.8 KFQ92808.1 - 1.8 7.7 17.0 2.4 7.2 17.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CENP-I PF07778.11 KFQ92808.1 - 3 6.4 7.6 4.4 5.9 7.6 1.2 1 0 0 1 1 1 0 Mis6 NOA36 PF06524.12 KFQ92808.1 - 6 6.1 27.3 0.099 11.9 20.4 1.6 2 0 0 2 2 2 0 NOA36 protein AAA PF00004.29 KFQ92809.1 - 7e-40 136.5 0.0 1.6e-39 135.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFQ92809.1 - 6.6e-14 51.4 2.5 1.5e-13 50.3 0.4 2.7 2 1 0 2 2 1 1 AAA+ lid domain Vps4_C PF09336.10 KFQ92809.1 - 1.2e-09 38.0 0.3 1.1e-08 34.9 0.0 2.7 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 KFQ92809.1 - 1.5e-05 24.8 0.0 2.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KFQ92809.1 - 2.2e-05 24.7 0.0 4.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KFQ92809.1 - 2.9e-05 24.3 0.0 5.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KFQ92809.1 - 4.3e-05 24.0 0.1 0.023 15.1 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KFQ92809.1 - 0.00019 21.4 0.3 0.0016 18.4 0.2 2.6 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KFQ92809.1 - 0.0003 20.1 0.0 0.00051 19.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 KFQ92809.1 - 0.00075 18.9 0.2 0.0016 17.8 0.2 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KFQ92809.1 - 0.0014 18.6 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KFQ92809.1 - 0.0026 17.8 0.0 0.0066 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFQ92809.1 - 0.0034 17.2 0.0 0.0072 16.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KFQ92809.1 - 0.005 17.4 0.3 0.024 15.2 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFQ92809.1 - 0.0052 17.1 0.6 0.076 13.3 0.2 2.6 2 1 1 3 3 3 1 AAA domain AAA_7 PF12775.7 KFQ92809.1 - 0.0081 15.7 0.3 0.019 14.5 0.2 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 KFQ92809.1 - 0.012 15.3 0.1 0.34 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KFQ92809.1 - 0.03 13.7 0.2 2.5 7.4 0.1 2.3 1 1 1 2 2 2 0 KaiC TPR_8 PF13181.6 KFQ92809.1 - 0.046 13.9 1.4 3.1 8.2 0.1 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat NACHT PF05729.12 KFQ92809.1 - 0.046 13.6 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 KFQ92809.1 - 0.054 13.7 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KFQ92809.1 - 0.056 12.9 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 KFQ92809.1 - 0.071 13.5 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Guanylate_kin PF00625.21 KFQ92809.1 - 0.13 11.9 0.0 0.49 10.1 0.0 1.9 2 0 0 2 2 2 0 Guanylate kinase AAA_30 PF13604.6 KFQ92809.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KFQ92809.1 - 0.16 11.5 0.3 0.54 9.8 0.3 1.9 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.6 KFQ92809.1 - 0.22 11.9 0.0 0.22 11.9 0.0 2.1 2 0 0 2 2 1 0 AAA domain TPR_2 PF07719.17 KFQ92809.1 - 0.65 10.2 2.0 35 4.8 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Rad60-SLD_2 PF13881.6 KFQ92811.1 - 3.7e-33 113.9 0.0 4.2e-33 113.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KFQ92811.1 - 8.9e-05 22.2 0.0 0.00019 21.1 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KFQ92811.1 - 0.045 14.3 0.0 0.06 13.9 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Met_gamma_lyase PF06838.11 KFQ92811.1 - 0.077 11.5 0.0 0.098 11.2 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase AA_permease_2 PF13520.6 KFQ92812.1 - 1.8e-53 181.9 25.4 1.8e-53 181.9 25.4 2.2 2 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 KFQ92812.1 - 5.4e-39 134.1 24.5 5.4e-39 134.1 24.5 2.3 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 KFQ92812.1 - 5.1e-25 87.3 9.6 5.1e-25 87.3 9.6 3.9 5 0 0 5 5 5 1 C-terminus of AA_permease DUF3278 PF11683.8 KFQ92812.1 - 1.1 9.4 11.6 0.24 11.5 0.9 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) RTBV_P46 PF06216.11 KFQ92813.1 - 0.32 9.8 8.3 0.086 11.7 2.6 2.1 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein MFS_1 PF07690.16 KFQ92815.1 - 1.2e-15 57.4 28.2 1.2e-15 57.4 28.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily UMP1 PF05348.11 KFQ92816.1 - 4.1e-38 130.2 0.1 4.9e-38 130.0 0.1 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Pkinase_Tyr PF07714.17 KFQ92817.1 - 7.7e-107 356.4 0.0 1.1e-106 355.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ92817.1 - 5.2e-45 153.9 0.0 8.2e-31 107.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.6 KFQ92817.1 - 6.6e-27 93.9 0.4 1.6e-14 54.2 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFQ92817.1 - 6.4e-26 90.2 0.0 3.6e-17 62.2 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFQ92817.1 - 1.3e-21 76.7 0.1 8.3e-11 42.1 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFQ92817.1 - 5.1e-18 65.0 0.1 1.8e-08 34.5 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain VEGFR-2_TMD PF17988.1 KFQ92817.1 - 1.8e-16 59.2 0.2 3.3e-16 58.4 0.2 1.4 1 0 0 1 1 1 1 VEGFR-2 Transmembrane domain V-set PF07686.17 KFQ92817.1 - 1.4e-09 38.1 1.2 0.00089 19.4 0.1 4.0 2 2 1 3 3 3 2 Immunoglobulin V-set domain Ig_4 PF16680.5 KFQ92817.1 - 1.2e-05 25.5 0.1 0.018 15.3 0.0 2.9 2 0 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 KFQ92817.1 - 0.00014 22.2 0.1 1 9.8 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFQ92817.1 - 0.0027 17.3 0.0 0.21 11.2 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain Haspin_kinase PF12330.8 KFQ92817.1 - 0.0088 15.0 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Izumo-Ig PF16706.5 KFQ92817.1 - 0.01 15.8 0.1 7.3 6.7 0.0 3.0 2 1 0 2 2 2 0 Izumo-like Immunoglobulin domain Herpes_gE PF02480.16 KFQ92817.1 - 0.034 12.9 0.0 0.14 10.8 0.0 1.8 1 1 0 2 2 2 0 Alphaherpesvirus glycoprotein E Pkinase_Tyr PF07714.17 KFQ92818.1 - 1.4e-102 342.4 0.0 2e-102 341.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ92818.1 - 4.7e-45 154.0 0.0 1.6e-28 99.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.6 KFQ92818.1 - 1.4e-07 32.0 8.1 0.77 10.4 0.1 5.9 6 0 0 6 6 6 2 Immunoglobulin domain I-set PF07679.16 KFQ92818.1 - 4.3e-06 26.7 8.0 0.11 12.6 0.1 5.4 5 1 1 6 6 6 2 Immunoglobulin I-set domain ig PF00047.25 KFQ92818.1 - 5e-06 26.6 0.1 0.0033 17.6 0.0 4.1 3 0 0 3 3 3 1 Immunoglobulin domain Haspin_kinase PF12330.8 KFQ92818.1 - 0.0003 19.9 0.4 0.0031 16.5 0.1 2.4 2 0 0 2 2 2 1 Haspin like kinase domain Ig_2 PF13895.6 KFQ92818.1 - 0.00036 20.8 2.1 0.033 14.5 0.0 3.9 3 0 0 3 3 3 1 Immunoglobulin domain APH PF01636.23 KFQ92818.1 - 0.067 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family MGC-24 PF05283.11 KFQ92818.1 - 0.97 9.9 5.4 1.2 9.6 1.1 3.0 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin WDCP PF15390.6 KFQ92819.1 - 0.74 8.1 4.8 0.66 8.3 4.8 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family LCD1 PF09798.9 KFQ92819.1 - 2.5 6.5 5.6 2.8 6.3 5.6 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein PDZ PF00595.24 KFQ92820.1 - 1.5e-65 217.6 1.7 8.8e-16 58.0 0.0 4.2 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 KFQ92820.1 - 5.1e-31 106.3 1.2 1e-07 31.7 0.1 4.4 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 KFQ92820.1 - 2.3e-17 63.1 0.2 7.6e-05 23.0 0.0 4.3 4 0 0 4 4 4 4 PDZ domain zf-C3HC4_2 PF13923.6 KFQ92820.1 - 2.7e-08 33.5 8.4 2.7e-08 33.5 8.4 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ92820.1 - 4.2e-08 32.9 6.7 4.2e-08 32.9 6.7 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ92820.1 - 6.2e-07 29.7 6.1 6.2e-07 29.7 6.1 3.4 5 0 0 5 5 3 1 Ring finger domain zf-RING_UBOX PF13445.6 KFQ92820.1 - 8.2e-07 28.9 7.9 8.2e-07 28.9 7.9 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFQ92820.1 - 2e-06 27.5 3.1 2e-06 27.5 3.1 3.2 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFQ92820.1 - 8.4e-06 25.6 5.4 8.4e-06 25.6 5.4 2.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFQ92820.1 - 9.2e-05 22.5 7.6 9.2e-05 22.5 7.6 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KFQ92820.1 - 0.0021 18.3 4.3 0.0021 18.3 4.3 2.4 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 KFQ92820.1 - 0.15 11.9 2.2 0.38 10.6 2.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KFQ92820.1 - 0.17 11.8 9.7 0.061 13.2 5.0 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KFQ92820.1 - 0.22 11.3 4.6 1.1 9.0 4.6 2.3 1 1 0 1 1 1 0 RING-like zinc finger eIF3g PF12353.8 KFQ92820.1 - 0.36 11.2 4.7 3.6 8.0 0.5 3.3 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G DZR PF12773.7 KFQ92820.1 - 0.62 10.1 10.3 1.3 9.1 5.9 3.1 2 1 0 2 2 2 0 Double zinc ribbon IF3_N PF05198.16 KFQ92821.1 - 3.7e-17 62.3 0.2 3.1e-16 59.4 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 KFQ92821.1 - 5.3e-09 35.9 0.5 1.6e-08 34.4 0.5 1.9 1 1 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain HTH_33 PF13592.6 KFQ92821.1 - 0.021 14.5 0.1 0.052 13.2 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix zf-C2H2 PF00096.26 KFQ92822.1 - 2.8e-31 106.2 57.8 2.6e-05 24.4 1.9 8.2 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ92822.1 - 1.2e-15 56.8 51.2 0.0039 17.9 0.9 8.3 8 0 0 8 8 8 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFQ92822.1 - 3.3e-15 55.7 61.3 5.1e-05 23.5 0.7 9.4 8 1 1 9 9 9 6 Zinc-finger double domain zf-C2H2_8 PF15909.5 KFQ92822.1 - 0.00039 20.6 25.0 0.035 14.4 6.5 4.3 1 1 5 6 6 6 4 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KFQ92822.1 - 0.00069 19.8 22.2 1.2 9.6 1.7 6.3 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFQ92822.1 - 0.0095 15.7 1.1 0.0095 15.7 1.1 7.8 10 0 0 10 10 9 2 C2H2-type zinc-finger domain zf_C2H2_ZHX PF18387.1 KFQ92822.1 - 0.02 14.5 0.4 0.02 14.5 0.4 4.2 1 1 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain CHORD PF04968.12 KFQ92822.1 - 0.022 15.5 41.2 1.1 10.1 0.4 6.8 2 2 5 7 7 7 0 CHORD zf-Di19 PF05605.12 KFQ92822.1 - 0.05 13.9 21.8 0.19 12.0 2.6 4.9 2 2 2 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding FOXP-CC PF16159.5 KFQ92822.1 - 0.06 14.0 28.0 0.77 10.4 0.0 6.4 2 1 5 7 7 7 0 FOXP coiled-coil domain zf_Hakai PF18408.1 KFQ92822.1 - 0.067 12.9 0.3 0.067 12.9 0.3 5.6 6 0 0 6 6 6 0 C2H2 Hakai zinc finger domain zf-C2H2_11 PF16622.5 KFQ92822.1 - 0.078 12.8 13.0 0.77 9.6 0.0 4.9 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-met PF12874.7 KFQ92822.1 - 1 9.9 21.0 24 5.5 1.0 6.9 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-MYST PF17772.1 KFQ92822.1 - 1.4 8.5 11.4 23 4.7 1.2 3.9 3 0 0 3 3 3 0 MYST family zinc finger domain Ribosomal_L37ae PF01780.19 KFQ92822.1 - 6.5 6.9 12.8 0.18 11.9 2.0 2.9 2 1 0 2 2 2 0 Ribosomal L37ae protein family Ribosomal_L21e PF01157.18 KFQ92824.1 - 3.1e-52 174.6 9.3 3.1e-52 174.6 9.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e Nudix_hydro PF18290.1 KFQ92824.1 - 0.0035 17.3 0.3 0.0055 16.7 0.3 1.3 1 0 0 1 1 1 1 Nudix hydrolase domain CLP_protease PF00574.23 KFQ92824.1 - 0.044 13.7 0.1 0.065 13.1 0.1 1.2 1 0 0 1 1 1 0 Clp protease UCH PF00443.29 KFQ92825.1 - 4.7e-61 206.5 1.9 5.5e-61 206.3 1.9 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFQ92825.1 - 2.4e-31 109.5 3.0 3.3e-31 109.1 3.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KFQ92825.1 - 0.0022 17.5 9.9 0.0045 16.5 7.0 2.4 2 1 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase CEBP_ZZ PF16366.5 KFQ92825.1 - 0.59 10.4 6.5 0.51 10.6 1.7 2.4 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain 7tm_1 PF00001.21 KFQ92826.1 - 1.5e-35 122.8 20.8 1.8e-35 122.6 20.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ92826.1 - 9.5e-06 25.2 11.9 9.5e-06 25.2 11.9 2.0 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFQ92826.1 - 3.6e-05 23.6 19.0 0.00017 21.4 19.0 2.4 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFQ92826.1 - 0.91 9.1 25.5 0.05 13.2 16.9 2.5 1 1 2 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srx WH2 PF02205.20 KFQ92827.1 - 4.1e-07 29.6 0.1 7.4e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 WH2 motif ChaB PF06150.12 KFQ92827.1 - 0.052 14.1 0.0 0.15 12.7 0.0 1.7 1 0 0 1 1 1 0 ChaB Pkinase PF00069.25 KFQ92828.1 - 7.9e-56 189.3 0.1 9.8e-56 189.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ92828.1 - 3.5e-20 72.4 0.0 5.7e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFQ92828.1 - 0.0059 16.6 0.1 0.0094 15.9 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFQ92828.1 - 0.012 14.9 0.1 0.027 13.8 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KFQ92828.1 - 0.12 11.3 0.1 0.63 9.0 0.0 1.8 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase PhoLip_ATPase_C PF16212.5 KFQ92829.1 - 1.4e-73 247.7 15.4 1.4e-73 247.7 15.4 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFQ92829.1 - 1.9e-19 69.1 0.8 1.9e-19 69.1 0.8 2.0 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KFQ92829.1 - 3.4e-14 52.7 0.0 1e-12 47.9 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFQ92829.1 - 4.8e-12 45.8 0.0 1.9e-11 43.8 0.0 2.0 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KFQ92829.1 - 5.2e-07 30.2 0.4 0.0051 17.1 0.2 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Colicin_im PF03857.13 KFQ92829.1 - 0.0017 18.3 0.2 0.0017 18.3 0.2 2.7 2 0 0 2 2 2 1 Colicin immunity protein Hydrolase_3 PF08282.12 KFQ92829.1 - 0.015 15.0 0.6 0.042 13.6 0.2 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Shisa PF13908.6 KFQ92830.1 - 2.8e-22 79.9 4.4 5.2e-22 79.0 4.4 1.6 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator Gag_MA PF01140.19 KFQ92830.1 - 0.032 14.0 1.2 0.047 13.4 0.2 1.6 1 1 1 2 2 2 0 Matrix protein (MA), p15 Rhabdo_glycop PF00974.18 KFQ92830.1 - 0.097 11.1 0.1 0.14 10.6 0.1 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Nucleoporin_FG2 PF15967.5 KFQ92831.1 - 0 1020.1 58.0 0 1019.9 58.0 1.0 1 0 0 1 1 1 1 Nucleoporin FG repeated region FapA PF03961.13 KFQ92831.1 - 0.0067 15.1 5.9 0.053 12.1 0.3 2.1 2 0 0 2 2 2 2 Flagellar Assembly Protein A Tox-ODYAM1 PF15642.6 KFQ92831.1 - 0.015 14.3 6.1 0.022 13.8 6.1 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus DUF1043 PF06295.12 KFQ92831.1 - 0.2 11.6 9.0 2.6 8.1 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) PSY3 PF16836.5 KFQ92831.1 - 0.22 11.0 2.6 0.13 11.8 0.3 1.7 2 0 0 2 2 2 0 Shu complex component Psy3, DNA-binding description DUF1664 PF07889.12 KFQ92831.1 - 0.63 10.1 7.1 3.6 7.7 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) COG2 PF06148.11 KFQ92831.1 - 1.8 8.6 8.1 3 8.0 1.1 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PHM7_cyt PF14703.6 KFQ92831.1 - 2.3 8.5 10.5 1.7 8.8 7.1 2.3 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter CENP-F_leu_zip PF10473.9 KFQ92831.1 - 2.6 8.1 14.4 2.7 8.0 0.4 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.10 KFQ92831.1 - 3.3 7.9 12.1 2.6 8.2 1.0 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Golgin_A5 PF09787.9 KFQ92831.1 - 6.3 6.2 16.8 0.33 10.4 3.1 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 Myotub-related PF06602.14 KFQ92832.1 - 2.3e-142 474.1 0.2 3.6e-142 473.5 0.2 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 KFQ92832.1 - 0.0018 18.1 0.2 0.026 14.3 0.0 2.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFQ92832.1 - 0.0047 16.5 0.0 0.016 14.8 0.0 1.9 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFQ92832.1 - 0.019 15.0 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF5560 PF17715.1 KFQ92834.1 - 2.2 7.7 8.1 0.087 12.3 0.9 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5560) RhoGEF PF00621.20 KFQ92835.1 - 1.9e-45 155.3 5.9 1.9e-45 155.3 5.9 1.8 2 0 0 2 2 2 1 RhoGEF domain SH3_1 PF00018.28 KFQ92835.1 - 2.7e-10 39.7 2.1 5.3e-10 38.7 2.1 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 KFQ92835.1 - 2.8e-10 40.6 0.6 6.4e-10 39.5 0.6 1.6 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.6 KFQ92835.1 - 5.7e-10 38.9 0.1 1e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFQ92835.1 - 1.1e-07 31.5 0.0 2.4e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH_5 PF15405.6 KFQ92835.1 - 0.0037 17.4 0.4 0.078 13.1 0.1 2.6 1 1 1 2 2 2 1 Pleckstrin homology domain Myosin_TH1 PF06017.13 KFQ92835.1 - 0.03 14.0 0.7 0.055 13.1 0.7 1.4 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding C1q PF00386.21 KFQ92836.1 - 3.2e-38 130.8 0.1 4e-38 130.5 0.1 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFQ92836.1 - 2.9e-29 100.6 80.2 1.3e-10 40.8 24.5 3.6 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) BclA_C PF18573.1 KFQ92836.1 - 6.4e-05 22.9 0.0 9.5e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 BclA C-terminal domain Peptidase_M3 PF01432.20 KFQ92837.1 - 8.8e-144 480.2 0.0 1.3e-143 479.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 DUF3126 PF11324.8 KFQ92837.1 - 0.011 15.5 0.1 0.025 14.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3126) Peptidase_M91 PF14891.6 KFQ92837.1 - 0.04 14.2 1.4 0.076 13.3 0.1 1.9 2 0 0 2 2 2 0 Effector protein VKG_Carbox PF05090.14 KFQ92837.1 - 0.084 11.7 0.1 0.13 11.1 0.1 1.1 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase Spore_III_AB PF09548.10 KFQ92837.1 - 0.23 11.6 0.5 0.95 9.5 0.1 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Peptidase_M32 PF02074.15 KFQ92837.1 - 0.58 8.8 2.2 1 8.0 0.4 2.2 2 1 1 3 3 3 0 Carboxypeptidase Taq (M32) metallopeptidase TNFR_c6 PF00020.18 KFQ92838.1 - 3.2e-08 33.8 17.5 8.6e-06 26.1 4.3 5.3 5 1 0 5 5 5 2 TNFR/NGFR cysteine-rich region HEPN PF05168.14 KFQ92839.1 - 1.2e-09 38.4 0.1 5.6e-09 36.1 0.1 2.3 1 0 0 1 1 1 1 HEPN domain DUF4368 PF14287.6 KFQ92839.1 - 0.0021 18.3 0.0 0.0067 16.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4368) HATPase_c_3 PF13589.6 KFQ92839.1 - 0.0024 17.7 0.1 53 3.6 0.0 4.9 3 2 0 3 3 3 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DnaJ PF00226.31 KFQ92839.1 - 0.003 17.7 0.3 0.01 16.0 0.3 1.9 1 0 0 1 1 1 1 DnaJ domain Sarcoglycan_1 PF04790.13 KFQ92840.1 - 6.7e-82 274.7 0.0 8.2e-82 274.5 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2345 PF10106.9 KFQ92840.1 - 0.0055 16.6 0.0 0.024 14.5 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2345) RVT_1 PF00078.27 KFQ92841.1 - 0.0032 17.0 0.0 0.0058 16.2 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) FGF PF00167.18 KFQ92843.1 - 1.9e-47 160.4 0.3 2.3e-47 160.2 0.3 1.1 1 0 0 1 1 1 1 Fibroblast growth factor EF-hand_7 PF13499.6 KFQ92845.1 - 6.3e-12 45.8 10.4 0.00024 21.5 0.1 4.6 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 KFQ92845.1 - 1.2e-08 34.7 12.8 1.5e-05 24.8 0.0 5.6 6 1 1 7 7 7 2 EF-hand domain pair EF-hand_1 PF00036.32 KFQ92845.1 - 8.1e-08 31.3 15.0 0.00083 18.7 0.2 5.5 6 0 0 6 6 6 2 EF hand EF-hand_6 PF13405.6 KFQ92845.1 - 2.9e-07 29.9 8.3 0.0033 17.2 0.2 4.2 5 0 0 5 5 5 2 EF-hand domain EF-hand_4 PF12763.7 KFQ92845.1 - 0.028 14.3 1.6 0.075 13.0 0.1 2.6 3 1 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand MHC_I PF00129.18 KFQ92845.1 - 0.039 13.5 0.4 0.089 12.3 0.4 1.6 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 EF-hand_5 PF13202.6 KFQ92845.1 - 0.21 11.2 8.1 13 5.5 1.1 3.8 3 0 0 3 3 3 0 EF hand DHHC PF01529.20 KFQ92846.1 - 4.6e-36 123.9 17.8 4.6e-36 123.9 17.8 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF599 PF04654.12 KFQ92846.1 - 0.19 11.1 0.0 0.19 11.1 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function, DUF599 Spt4 PF06093.13 KFQ92846.1 - 1.2 9.3 6.3 2.4 8.3 6.3 1.5 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger MRP-63 PF14978.6 KFQ92847.1 - 9.2e-37 125.6 5.0 1e-36 125.4 5.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosome protein 63 DUF1623 PF07785.11 KFQ92848.1 - 0.045 13.9 0.1 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1623) SAP18 PF06487.12 KFQ92849.1 - 4.7e-40 137.0 0.0 5.9e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Pkinase PF00069.25 KFQ92851.1 - 2.2e-61 207.5 0.1 2.8e-39 135.1 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ92851.1 - 6.5e-29 101.0 0.1 3.8e-20 72.3 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_C PF00433.24 KFQ92851.1 - 5.4e-05 23.8 2.4 0.00018 22.1 2.4 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain UBA PF00627.31 KFQ92851.1 - 0.00014 21.6 0.4 0.00028 20.7 0.4 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Haspin_kinase PF12330.8 KFQ92851.1 - 0.00088 18.3 1.5 0.0018 17.3 1.5 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFQ92851.1 - 0.0039 17.1 0.1 0.046 13.6 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFQ92851.1 - 0.01 15.2 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KFQ92851.1 - 0.024 13.7 0.1 0.047 12.7 0.1 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.6 KFQ92851.1 - 0.039 13.3 0.1 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 Kinase-like CRM1_C PF08767.11 KFQ92852.1 - 2.4e-05 23.7 1.1 2.4e-05 23.7 1.1 2.3 2 0 0 2 2 2 1 CRM1 C terminal N6-adenineMlase PF10237.9 KFQ92853.1 - 2.6e-57 193.1 0.0 3.2e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 KFQ92853.1 - 0.00036 20.2 0.0 0.0006 19.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 IL17 PF06083.11 KFQ92854.1 - 4.2e-28 97.6 0.4 5.9e-28 97.2 0.4 1.2 1 0 0 1 1 1 1 Interleukin-17 3HCDH_N PF02737.18 KFQ92855.1 - 6.3e-49 166.3 0.0 8.2e-49 165.9 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KFQ92855.1 - 4.5e-15 56.0 0.0 8.3e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Connexin PF00029.19 KFQ92856.1 - 2.5e-88 295.8 11.1 2.5e-88 295.8 11.1 2.3 2 1 0 2 2 2 1 Connexin Ninjurin PF04923.12 KFQ92856.1 - 0.21 11.5 2.3 0.32 10.9 0.0 2.3 3 1 0 3 3 3 0 Ninjurin Connexin PF00029.19 KFQ92857.1 - 3.9e-87 291.9 11.6 2.5e-85 286.0 11.6 2.0 1 1 0 1 1 1 1 Connexin Connexin PF00029.19 KFQ92858.1 - 2.2e-102 341.8 0.0 2.9e-102 341.4 0.0 1.1 1 0 0 1 1 1 1 Connexin Connexin40_C PF16791.5 KFQ92858.1 - 3.2e-09 38.0 0.3 1.7e-06 29.3 0.1 2.5 2 0 0 2 2 2 2 Connexin 40 C-terminal domain RRM_1 PF00076.22 KFQ92859.1 - 1e-33 114.9 0.0 4.1e-16 58.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.11 KFQ92859.1 - 2.9e-20 72.2 0.3 7.2e-20 70.9 0.3 1.7 1 0 0 1 1 1 1 NOPS (NUC059) domain RRM_7 PF16367.5 KFQ92859.1 - 8.3e-05 22.6 0.0 0.0014 18.7 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif Ank_2 PF12796.7 KFQ92860.1 - 1.6e-19 70.3 1.2 1.4e-10 41.6 0.2 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFQ92860.1 - 5.9e-19 67.9 0.3 1.2e-09 38.2 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFQ92860.1 - 2.8e-17 62.9 0.4 8.7e-09 35.7 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ92860.1 - 6.5e-13 47.6 0.5 4.2e-05 23.6 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KFQ92860.1 - 1.3e-09 38.0 0.6 0.00032 21.0 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Chromo PF00385.24 KFQ92860.1 - 2.8e-09 36.7 0.7 9.9e-09 35.0 0.7 2.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tcp10_C PF07202.13 KFQ92861.1 - 3.2e-86 287.7 7.7 3.2e-86 287.7 7.7 1.5 1 1 0 1 1 1 1 T-complex protein 10 C-terminus PepSY_like PF11396.8 KFQ92861.1 - 0.0079 16.7 1.3 0.06 13.9 0.2 2.6 1 1 1 2 2 2 1 Putative beta-lactamase-inhibitor-like, PepSY-like Plant_vir_prot PF01307.17 KFQ92861.1 - 0.012 15.8 0.4 4.7 7.5 0.0 2.6 1 1 2 3 3 3 0 Plant viral movement protein SH3_15 PF18346.1 KFQ92861.1 - 0.035 14.4 1.5 39 4.7 0.0 3.9 2 2 1 3 3 3 0 Mind bomb SH3 repeat domain FecR PF04773.13 KFQ92861.1 - 0.038 14.6 0.4 6.6 7.4 0.1 3.6 1 1 1 2 2 2 0 FecR protein DUF348 PF03990.14 KFQ92861.1 - 2.4 7.9 4.4 1.7 8.5 0.4 2.7 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain TUDOR PF00567.24 KFQ92862.1 - 3.5e-93 307.9 11.9 1.3e-21 76.9 0.2 7.7 7 1 0 7 7 7 5 Tudor domain Agenet PF05641.12 KFQ92862.1 - 1.9e-11 44.3 2.5 0.07 13.6 0.0 5.1 5 0 0 5 5 5 3 Agenet domain Tudor_2 PF18104.1 KFQ92862.1 - 0.0041 16.8 0.3 0.54 10.0 0.0 3.4 3 0 0 3 3 3 1 Jumonji domain-containing protein 2A Tudor domain Tudor-knot PF11717.8 KFQ92862.1 - 0.019 14.9 0.0 11 6.0 0.0 3.4 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain Tudor_3 PF18115.1 KFQ92862.1 - 0.087 12.7 0.0 54 3.8 0.0 3.7 4 0 0 4 4 4 0 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 KFQ92862.1 - 0.17 11.9 0.0 8.3 6.5 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4537) RA PF00788.23 KFQ92863.1 - 3.1e-13 50.1 0.0 1.2e-12 48.3 0.0 2.0 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain IQ_SEC7_PH PF16453.5 KFQ92863.1 - 0.0039 17.2 0.2 0.021 14.8 0.1 2.2 2 1 1 3 3 3 1 PH domain PH PF00169.29 KFQ92863.1 - 0.014 15.9 0.9 0.14 12.7 0.3 2.5 2 1 0 2 2 2 0 PH domain Ras_bdg_2 PF14847.6 KFQ92863.1 - 0.029 14.7 0.0 0.074 13.4 0.0 1.7 1 0 0 1 1 1 0 Ras-binding domain of Byr2 PH_16 PF17838.1 KFQ92863.1 - 0.052 13.4 0.7 0.16 11.8 0.1 1.9 2 0 0 2 2 2 0 PH domain PH_10 PF15411.6 KFQ92863.1 - 0.12 12.6 0.9 1 9.6 0.9 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain RhoGAP PF00620.27 KFQ92864.1 - 2.2e-40 138.0 0.0 2.8e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain Nod1 PF17114.5 KFQ92864.1 - 4.6e-07 30.1 0.1 3.6e-06 27.2 0.1 2.0 1 1 0 1 1 1 1 Gef2-related medial cortical node protein Nod1 DUF2183 PF09949.9 KFQ92864.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) RHH_7 PF16777.5 KFQ92865.1 - 0.0076 16.6 2.6 0.027 14.9 0.1 2.7 3 0 0 3 3 3 1 Transcriptional regulator, RHH-like, CopG Fer2 PF00111.27 KFQ92866.1 - 1.1e-07 31.7 0.2 1.4e-07 31.3 0.2 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain CTU2 PF10288.9 KFQ92866.1 - 0.025 14.8 0.0 0.12 12.6 0.0 1.9 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Zf_RING PF16744.5 KFQ92866.1 - 0.042 14.0 0.4 0.5 10.5 0.5 2.0 1 1 1 2 2 2 0 KIAA1045 RING finger zf-CHY PF05495.12 KFQ92866.1 - 0.048 14.2 0.4 0.089 13.3 0.4 1.4 1 1 0 1 1 1 0 CHY zinc finger ERM PF00769.19 KFQ92867.1 - 2.8e-76 256.6 52.8 2.8e-76 256.6 52.8 2.5 2 1 1 3 3 3 1 Ezrin/radixin/moesin family FERM_C PF09380.10 KFQ92867.1 - 3.8e-28 97.7 0.0 1.4e-27 95.9 0.0 2.0 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 KFQ92867.1 - 1.1e-27 96.8 1.5 1.1e-27 96.8 1.5 3.6 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.10 KFQ92867.1 - 3.3e-15 55.8 0.8 1.7e-14 53.5 0.1 2.5 2 0 0 2 2 2 1 FERM N-terminal domain RNase_Zc3h12a PF11977.8 KFQ92868.1 - 2.1e-66 222.5 0.0 2.8e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain UBA_6 PF18039.1 KFQ92868.1 - 9.7e-21 73.4 1.8 1.8e-20 72.5 1.8 1.5 1 0 0 1 1 1 1 UBA-like domain zf-CCCH_4 PF18044.1 KFQ92868.1 - 9.9e-05 22.0 7.0 0.00017 21.3 7.0 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Omega-toxin PF06357.11 KFQ92868.1 - 0.011 15.5 4.8 0.021 14.6 4.8 1.3 1 0 0 1 1 1 0 Omega-atracotoxin PRORP PF16953.5 KFQ92868.1 - 0.067 12.7 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein-only RNase P zf-CCCH_2 PF14608.6 KFQ92868.1 - 1.1 9.8 9.6 2.6 8.7 9.6 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 KFQ92868.1 - 1.2 9.2 8.3 9 6.3 8.3 2.1 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CD34_antigen PF06365.12 KFQ92870.1 - 5.5e-05 22.8 0.1 7e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family TMEM154 PF15102.6 KFQ92870.1 - 0.0091 15.9 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family LapA_dom PF06305.11 KFQ92870.1 - 0.01 15.7 0.2 0.018 14.9 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF4834 PF16118.5 KFQ92870.1 - 0.031 15.2 0.0 0.042 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TssO PF17561.2 KFQ92870.1 - 0.031 14.4 0.8 0.041 14.0 0.8 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO DUF3169 PF11368.8 KFQ92870.1 - 0.033 13.7 0.0 0.041 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) MSA-2c PF12238.8 KFQ92870.1 - 0.034 14.2 0.0 0.035 14.1 0.0 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF3328 PF11807.8 KFQ92870.1 - 0.039 13.7 0.0 0.05 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DUF2663 PF10864.8 KFQ92870.1 - 0.042 14.2 0.1 0.051 14.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) EphA2_TM PF14575.6 KFQ92870.1 - 0.043 14.7 0.0 0.066 14.1 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain OAD_gamma PF04277.13 KFQ92870.1 - 0.044 14.4 0.0 0.081 13.5 0.0 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain OSTbeta PF15048.6 KFQ92870.1 - 0.045 13.9 0.0 0.058 13.5 0.0 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein SieB PF14163.6 KFQ92870.1 - 0.061 12.8 0.5 0.081 12.4 0.5 1.1 1 0 0 1 1 1 0 Super-infection exclusion protein B Tmemb_9 PF05434.11 KFQ92870.1 - 0.074 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 TMEM9 IgaA PF07095.11 KFQ92870.1 - 0.12 10.3 0.3 0.15 10.1 0.3 1.0 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA ATP-synt_8 PF00895.20 KFQ92870.1 - 0.13 12.8 0.4 0.23 11.9 0.4 1.4 1 0 0 1 1 1 0 ATP synthase protein 8 DUF2207 PF09972.9 KFQ92870.1 - 0.17 10.6 0.0 0.21 10.3 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Brr6_like_C_C PF10104.9 KFQ92870.1 - 1.2 9.0 5.7 1.2 8.9 4.3 1.6 1 1 1 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain DEAD PF00270.29 KFQ92871.1 - 2.9e-46 157.4 1.1 9.5e-46 155.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFQ92871.1 - 8.2e-26 90.5 0.1 9.8e-25 87.1 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFQ92871.1 - 9.2e-18 64.2 0.3 2.1e-17 63.1 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KFQ92871.1 - 1.4e-10 41.5 0.0 1.4e-10 41.5 0.0 3.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Glyco_transf_90 PF05686.12 KFQ92873.1 - 1.8e-85 287.3 0.4 2.2e-85 286.9 0.4 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KFQ92873.1 - 0.0011 19.3 0.0 0.0021 18.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Filamin PF00630.19 KFQ92873.1 - 0.003 18.3 0.0 0.0056 17.5 0.0 1.5 1 0 0 1 1 1 1 Filamin/ABP280 repeat PI3_PI4_kinase PF00454.27 KFQ92874.1 - 8.8e-53 179.7 0.2 3.1e-52 177.9 0.1 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KFQ92874.1 - 5.5e-46 157.4 12.3 1.5e-45 155.9 12.3 1.8 1 0 0 1 1 1 1 FAT domain TAN PF11640.8 KFQ92874.1 - 2.9e-24 85.9 2.8 2.9e-24 85.9 2.8 5.0 6 0 0 6 6 6 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 KFQ92874.1 - 1e-12 47.6 0.1 2.7e-12 46.3 0.1 1.8 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 KFQ92874.1 - 0.0084 16.3 2.3 0.44 10.9 0.2 4.4 4 0 0 4 4 4 1 HEAT repeat Thiolase_N PF00108.23 KFQ92875.1 - 2.1e-95 319.0 3.2 3e-95 318.5 3.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFQ92875.1 - 5.4e-46 155.2 3.2 9.8e-46 154.4 1.3 2.2 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFQ92875.1 - 6.7e-06 25.9 6.8 9.6e-06 25.4 2.5 2.7 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 KFQ92875.1 - 0.03 14.5 0.6 0.29 11.3 0.0 2.6 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Ras PF00071.22 KFQ92876.1 - 3.3e-29 101.6 0.1 3.9e-29 101.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ92876.1 - 5e-06 26.7 0.0 1e-05 25.7 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ92876.1 - 0.028 13.9 0.0 0.035 13.6 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family zf-C2H2_3 PF13878.6 KFQ92876.1 - 0.073 12.9 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO SLC35F PF06027.12 KFQ92878.1 - 2.2e-136 454.3 29.3 2.5e-136 454.1 29.3 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KFQ92878.1 - 2e-10 40.1 4.8 2e-10 40.1 4.8 2.0 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KFQ92878.1 - 2.2e-10 40.8 35.9 8.6e-06 26.0 18.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family ELMO_CED12 PF04727.13 KFQ92879.1 - 2.7e-47 161.1 0.1 4.5e-47 160.4 0.1 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family 2OG-FeII_Oxy_2 PF13532.6 KFQ92880.1 - 1.7e-21 77.3 0.0 3.9e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.12 KFQ92880.1 - 1.1e-13 51.6 0.0 3.1e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFQ92880.1 - 8.9e-12 45.6 0.1 2.6e-11 44.1 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain RRM_1 PF00076.22 KFQ92880.1 - 1.7e-08 34.1 0.0 4e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_8 PF05148.15 KFQ92880.1 - 2.5e-05 24.2 0.0 4.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_23 PF13489.6 KFQ92880.1 - 8e-05 22.5 0.0 0.0005 19.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFQ92880.1 - 9.3e-05 22.3 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFQ92880.1 - 9.7e-05 23.0 0.0 0.00027 21.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain DUF1891 PF09004.10 KFQ92880.1 - 0.00091 18.8 0.4 0.0022 17.6 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1891) Ubie_methyltran PF01209.18 KFQ92880.1 - 0.029 13.7 0.0 0.088 12.1 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MetW PF07021.12 KFQ92880.1 - 0.057 13.0 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 KFQ92880.1 - 0.067 13.1 0.1 7.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain 2OG-FeII_Oxy PF03171.20 KFQ92880.1 - 0.073 13.6 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Methyltransf_9 PF08003.11 KFQ92880.1 - 0.088 11.7 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) CwfJ_C_1 PF04677.15 KFQ92882.1 - 4.3e-18 65.3 1.3 5.1e-10 39.3 0.1 2.2 2 0 0 2 2 2 2 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KFQ92882.1 - 3.6e-14 53.4 2.1 6.1e-14 52.7 0.0 2.3 3 0 0 3 3 3 1 Protein similar to CwfJ C-terminus 2 VOMI PF03762.17 KFQ92883.1 - 1.1e-51 175.4 0.5 1.3e-51 175.1 0.5 1.1 1 0 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) VOMI PF03762.17 KFQ92884.1 - 1.4e-46 158.7 1.5 1.8e-46 158.4 1.5 1.1 1 0 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) Guanylate_cyc PF00211.20 KFQ92885.1 - 3.4e-62 209.3 0.0 5.6e-62 208.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KFQ92885.1 - 7.9e-50 169.3 2.7 5.4e-48 163.3 2.7 2.3 1 1 0 1 1 1 1 Heme NO binding associated HNOB PF07700.15 KFQ92885.1 - 1.2e-15 57.9 0.2 1.9e-15 57.2 0.2 1.3 1 0 0 1 1 1 1 Haem-NO-binding DUF4761 PF15958.5 KFQ92885.1 - 0.13 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4761) ACPS PF01648.20 KFQ92887.1 - 2.5e-18 66.3 0.1 3.9e-16 59.2 0.0 2.2 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase superfamily BTB PF00651.31 KFQ92888.1 - 3.4e-27 94.9 0.9 3.4e-27 94.9 0.9 2.2 2 0 0 2 2 2 1 BTB/POZ domain Kelch_6 PF13964.6 KFQ92888.1 - 2.7e-26 90.9 3.6 2.1e-05 24.6 0.0 6.7 3 1 3 6 6 6 5 Kelch motif BACK PF07707.15 KFQ92888.1 - 4.6e-26 90.9 3.0 4.6e-26 90.9 3.0 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_1 PF01344.25 KFQ92888.1 - 1.1e-25 88.9 7.5 1.3e-06 27.8 0.0 6.3 6 1 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KFQ92888.1 - 8.2e-12 44.9 0.0 0.08 13.0 0.0 5.1 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KFQ92888.1 - 2.1e-09 37.4 0.1 1 9.8 0.0 5.1 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KFQ92888.1 - 1.9e-06 27.6 5.2 0.11 12.6 0.0 5.8 6 1 0 6 6 6 2 Kelch motif Kelch_5 PF13854.6 KFQ92888.1 - 0.0058 16.6 0.6 4.6 7.3 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Myb_DNA-bind_5 PF13873.6 KFQ92889.1 - 2.9e-23 81.7 6.9 2.9e-23 81.7 6.9 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 KFQ92889.1 - 0.00036 20.7 0.9 0.00036 20.7 0.9 2.5 3 0 0 3 3 3 1 Myb-like DNA-binding domain Flagellin_C PF00700.21 KFQ92889.1 - 0.29 11.5 2.1 0.76 10.2 0.5 2.4 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region ANF_receptor PF01094.28 KFQ92890.1 - 1.5e-65 221.6 0.0 2.2e-65 221.1 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 KFQ92890.1 - 3.2e-59 199.1 0.0 5.1e-59 198.4 0.0 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFQ92890.1 - 1.1e-44 151.3 0.3 2.4e-44 150.2 0.0 1.7 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFQ92890.1 - 1.4e-23 83.5 0.0 2.5e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.6 KFQ92890.1 - 0.00098 18.9 0.0 0.012 15.3 0.0 2.3 2 1 0 2 2 2 1 Periplasmic binding protein Ion_trans_2 PF07885.16 KFQ92890.1 - 5.3 7.1 7.4 5.2 7.1 0.1 3.4 3 0 0 3 3 3 0 Ion channel Yae1_N PF09811.9 KFQ92892.1 - 1.8e-09 37.1 26.3 1.2 8.9 26.3 3.1 1 1 0 1 1 1 1 Essential protein Yae1, N terminal CUB PF00431.20 KFQ92894.1 - 2.6e-20 72.8 0.0 4e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 CUB domain PDGF PF00341.17 KFQ92894.1 - 3.2e-11 43.4 4.2 5.5e-11 42.6 4.2 1.4 1 0 0 1 1 1 1 PDGF/VEGF domain HTH_Tnp_Mu_2 PF09039.11 KFQ92894.1 - 0.035 14.2 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Mu DNA binding, I gamma subdomain AAA_6 PF12774.7 KFQ92896.1 - 1.6e-130 434.9 0.0 1.2e-129 432.0 0.0 2.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KFQ92896.1 - 5.8e-108 361.5 4.8 5.8e-108 361.5 4.8 5.3 6 0 0 6 6 5 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KFQ92896.1 - 7.2e-68 228.0 2.9 7.2e-68 228.0 2.9 4.9 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 KFQ92896.1 - 8.4e-57 192.4 0.2 5.4e-53 180.0 0.1 4.1 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KFQ92896.1 - 2.5e-41 141.9 0.6 2.5e-41 141.9 0.6 3.0 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 KFQ92896.1 - 6.1e-39 133.5 0.0 2e-38 131.8 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KFQ92896.1 - 9.9e-37 126.0 0.0 2e-23 82.9 0.0 5.7 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) DHC_N1 PF08385.12 KFQ92896.1 - 1.7e-35 122.7 0.2 1.7e-35 122.7 0.2 4.8 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 Dynein_heavy PF03028.15 KFQ92896.1 - 3.1e-35 120.8 0.1 8.8e-34 116.2 0.1 3.3 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_7 PF12775.7 KFQ92896.1 - 2.6e-28 98.7 0.6 9.2e-25 87.2 0.0 3.5 3 0 0 3 3 3 2 P-loop containing dynein motor region MT PF12777.7 KFQ92896.1 - 1.4e-25 90.1 13.7 2e-25 89.6 12.4 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_22 PF13401.6 KFQ92896.1 - 1.2e-09 38.6 1.5 0.019 15.2 0.0 5.3 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.6 KFQ92896.1 - 2.8e-08 34.3 16.4 0.0007 20.0 0.0 8.2 8 1 0 8 8 7 2 AAA ATPase domain RsgA_GTPase PF03193.16 KFQ92896.1 - 1.2e-06 28.5 0.4 0.00025 21.0 0.0 4.2 4 0 0 4 4 4 1 RsgA GTPase AAA PF00004.29 KFQ92896.1 - 5.6e-06 26.8 0.7 0.6 10.5 0.0 4.5 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KFQ92896.1 - 4.6e-05 23.2 0.9 0.032 14.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 KFQ92896.1 - 0.0012 18.6 0.6 0.28 10.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KFQ92896.1 - 0.0022 18.5 16.2 0.0026 18.3 0.0 5.2 7 0 0 7 7 3 2 ABC transporter RNA_helicase PF00910.22 KFQ92896.1 - 0.0025 18.2 0.3 1.1 9.6 0.0 3.9 3 0 0 3 3 3 1 RNA helicase AAA_29 PF13555.6 KFQ92896.1 - 0.0029 17.3 0.0 0.29 10.9 0.0 3.5 3 0 0 3 3 3 1 P-loop containing region of AAA domain Rad17 PF03215.15 KFQ92896.1 - 0.0038 17.2 0.6 5.7 6.8 0.0 4.4 4 0 0 4 4 4 0 Rad17 P-loop domain AAA_18 PF13238.6 KFQ92896.1 - 0.0073 16.9 0.1 1.7 9.2 0.0 4.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KFQ92896.1 - 0.0088 16.3 0.2 0.35 11.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KFQ92896.1 - 0.012 15.4 0.7 0.44 10.3 0.0 3.1 3 0 0 3 3 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 KFQ92896.1 - 0.012 14.9 0.0 0.11 11.8 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 KFQ92896.1 - 0.026 14.5 1.0 11 5.9 0.1 4.3 3 0 0 3 3 3 0 NACHT domain AAA_33 PF13671.6 KFQ92896.1 - 0.029 14.5 2.5 0.093 12.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 KFQ92896.1 - 0.064 13.2 11.6 0.12 12.3 0.0 5.0 5 0 0 5 5 3 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 KFQ92896.1 - 0.071 13.6 0.0 0.071 13.6 0.0 9.7 10 1 0 10 10 9 0 AAA domain TsaE PF02367.17 KFQ92896.1 - 0.18 11.8 0.6 0.97 9.4 0.0 2.5 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ERM PF00769.19 KFQ92896.1 - 0.69 9.7 50.7 0.0059 16.5 12.4 4.1 4 0 0 4 4 4 0 Ezrin/radixin/moesin family DUF2968 PF11180.8 KFQ92896.1 - 1.6 8.4 24.0 0.25 10.9 8.8 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DUF641 PF04859.12 KFQ92896.1 - 9.5 6.6 20.2 0.062 13.6 2.9 4.4 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) Cullin_binding PF03556.15 KFQ92897.1 - 2.5e-30 105.4 4.5 3.6e-30 104.9 4.5 1.2 1 0 0 1 1 1 1 Cullin binding Peptidase_M10 PF00413.24 KFQ92898.1 - 3e-65 218.9 0.0 4.8e-65 218.2 0.0 1.3 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 KFQ92898.1 - 8.4e-42 140.9 3.5 9.4e-13 47.9 0.0 4.4 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 KFQ92898.1 - 2.9e-11 43.4 0.1 5.1e-11 42.6 0.1 1.4 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.24 KFQ92898.1 - 0.0097 15.5 0.1 3.3 7.3 0.0 2.4 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 KFQ92898.1 - 0.012 16.2 0.0 0.032 14.7 0.0 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFQ92898.1 - 0.044 13.4 0.1 0.087 12.5 0.0 1.4 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 KFQ92898.1 - 0.057 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Met-zincin Reprolysin_5 PF13688.6 KFQ92898.1 - 0.067 13.3 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 MerR_2 PF13591.6 KFQ92898.1 - 0.09 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 MerR HTH family regulatory protein Peptidase_M10 PF00413.24 KFQ92899.1 - 3.8e-61 205.6 0.1 8.1e-61 204.5 0.1 1.6 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 KFQ92899.1 - 6.5e-45 150.8 10.4 1.2e-14 54.0 0.1 4.4 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 KFQ92899.1 - 1.3e-11 44.5 0.0 2.4e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.24 KFQ92899.1 - 0.0031 17.1 0.1 1.8 8.1 0.1 2.3 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 KFQ92899.1 - 0.0073 16.8 0.2 0.021 15.4 0.2 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFQ92899.1 - 0.083 13.0 0.8 0.16 12.1 0.8 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF4953 PF16313.5 KFQ92899.1 - 0.15 11.2 0.4 0.32 10.1 0.4 1.5 1 0 0 1 1 1 0 Met-zincin Reprolysin_4 PF13583.6 KFQ92899.1 - 0.17 11.5 0.1 0.31 10.6 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFQ92900.1 - 9.9e-62 207.5 0.1 1.9e-61 206.6 0.0 1.5 2 0 0 2 2 2 1 Matrixin Hemopexin PF00045.19 KFQ92900.1 - 8.4e-37 124.9 9.7 2.7e-12 46.4 0.6 4.3 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 KFQ92900.1 - 6.9e-10 39.0 0.1 1.7e-09 37.7 0.1 1.8 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.24 KFQ92900.1 - 0.00016 21.4 0.4 0.41 10.2 0.1 2.4 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 KFQ92900.1 - 0.00047 20.7 0.1 0.0018 18.8 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFQ92900.1 - 0.002 17.8 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFQ92900.1 - 0.0028 17.8 0.0 0.004 17.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M54 PF07998.11 KFQ92900.1 - 0.01 15.9 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M54 DUF4953 PF16313.5 KFQ92900.1 - 0.046 12.9 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Met-zincin Peptidase_M66 PF10462.9 KFQ92900.1 - 0.065 12.2 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M57 PF12388.8 KFQ92900.1 - 0.093 12.3 0.2 0.16 11.6 0.2 1.2 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.24 KFQ92901.1 - 5.5e-60 201.8 0.0 9.2e-60 201.1 0.0 1.4 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 KFQ92901.1 - 6.6e-41 138.0 7.0 1.6e-12 47.2 0.2 4.3 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 KFQ92901.1 - 1.7e-15 57.0 0.1 3.4e-15 56.0 0.1 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Reprolysin_3 PF13582.6 KFQ92901.1 - 0.0025 18.3 0.0 0.0055 17.2 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 KFQ92901.1 - 0.0054 16.4 0.1 0.65 9.6 0.1 2.3 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.6 KFQ92901.1 - 0.029 14.5 0.0 0.047 13.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 KFQ92901.1 - 0.047 12.6 0.1 0.086 11.8 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_4 PF13583.6 KFQ92901.1 - 0.05 13.2 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 KFQ92901.1 - 0.074 12.3 0.2 0.12 11.5 0.2 1.3 1 0 0 1 1 1 0 Met-zincin Peptidase_M54 PF07998.11 KFQ92901.1 - 0.16 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 Peptidase_M10 PF00413.24 KFQ92902.1 - 3.8e-63 212.0 0.0 6.1e-63 211.4 0.0 1.3 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.18 KFQ92902.1 - 9.7e-09 35.3 0.0 1.7e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.24 KFQ92902.1 - 0.0029 17.3 0.2 0.4 10.3 0.1 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) DUF4953 PF16313.5 KFQ92902.1 - 0.022 14.0 0.1 0.036 13.3 0.1 1.3 1 0 0 1 1 1 0 Met-zincin Peptidase_M66 PF10462.9 KFQ92902.1 - 0.028 13.4 0.1 0.04 12.9 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.6 KFQ92902.1 - 0.032 14.8 1.2 0.054 14.0 1.2 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFQ92902.1 - 0.044 13.9 0.1 0.067 13.3 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KFQ92902.1 - 0.045 13.4 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 KFQ92902.1 - 0.089 11.4 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family MGC-24 PF05283.11 KFQ92903.1 - 9.1e-09 35.9 8.7 1.2e-08 35.5 8.7 1.3 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin FSA_C PF10479.9 KFQ92903.1 - 1.3 7.1 9.1 1.3 7.1 9.1 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus BIR PF00653.21 KFQ92904.1 - 7.8e-65 215.5 14.6 1.2e-21 77.1 0.8 3.9 4 0 0 4 4 4 3 Inhibitor of Apoptosis domain CARD PF00619.21 KFQ92904.1 - 1.5e-22 79.4 0.2 3.6e-22 78.2 0.2 1.7 1 0 0 1 1 1 1 Caspase recruitment domain zf-C3HC4_3 PF13920.6 KFQ92904.1 - 1.3e-14 53.8 8.2 1.3e-14 53.8 8.2 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFQ92904.1 - 2.8e-07 30.3 7.9 2.8e-07 30.3 7.9 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC PF07967.13 KFQ92904.1 - 1.1e-06 28.8 2.5 0.62 10.1 0.1 3.7 3 0 0 3 3 3 3 C3HC zinc finger-like zf-RING_5 PF14634.6 KFQ92904.1 - 0.0056 16.6 7.1 0.0056 16.6 7.1 2.4 2 0 0 2 2 2 1 zinc-RING finger domain DUF2039 PF10217.9 KFQ92904.1 - 0.11 12.9 4.4 0.34 11.3 4.4 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) RNA_pol_N PF01194.17 KFQ92904.1 - 0.11 12.8 6.7 2.9 8.3 0.0 3.3 3 0 0 3 3 3 0 RNA polymerases N / 8 kDa subunit zf-RING_UBOX PF13445.6 KFQ92904.1 - 0.29 11.2 6.2 0.69 10.0 3.5 2.7 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFQ92904.1 - 0.41 10.5 13.4 0.21 11.4 9.9 2.5 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) WW PF00397.26 KFQ92905.1 - 5.6e-22 77.5 2.6 2.9e-10 40.1 0.1 2.4 2 0 0 2 2 2 2 WW domain MbtH PF03621.13 KFQ92905.1 - 0.0092 15.4 0.0 0.8 9.2 0.0 2.4 2 0 0 2 2 2 2 MbtH-like protein TFIIA PF03153.13 KFQ92905.1 - 1.6 8.6 9.9 2.1 8.3 9.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4498 PF14926.6 KFQ92906.1 - 9.3e-82 274.0 1.1 1e-81 273.9 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) Fibrinogen_C PF00147.18 KFQ92907.1 - 1.8e-58 198.0 3.8 2.5e-58 197.5 3.8 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Helicase_C PF00271.31 KFQ92909.1 - 2.2e-15 57.0 0.0 4.5e-15 55.9 0.0 1.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C_4 PF13871.6 KFQ92909.1 - 0.032 13.9 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 C-terminal domain on Strawberry notch homologue Glyco_transf_29 PF00777.18 KFQ92910.1 - 7e-19 68.3 0.0 8.6e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Zona_pellucida PF00100.23 KFQ92911.1 - 1.1e-05 25.4 0.0 1.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Zona pellucida-like domain Mur_ligase_M PF08245.12 KFQ92912.1 - 0.012 15.6 0.0 0.46 10.4 0.0 2.2 1 1 0 1 1 1 0 Mur ligase middle domain Mur_ligase_C PF02875.21 KFQ92912.1 - 0.056 13.7 0.0 0.099 12.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Pkinase PF00069.25 KFQ92913.1 - 2.4e-70 236.9 0.0 2.8e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ92913.1 - 5e-33 114.5 0.0 6.5e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFQ92913.1 - 1.8e-07 30.5 0.1 2.4e-07 30.1 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFQ92913.1 - 0.00086 18.7 0.1 0.44 9.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KFQ92913.1 - 0.04 12.7 0.0 0.077 11.8 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase RIO1 PF01163.22 KFQ92913.1 - 0.6 9.7 3.7 0.49 10.0 0.9 2.1 2 1 0 2 2 2 0 RIO1 family Torsin PF06309.11 KFQ92914.1 - 3.3e-39 133.9 0.1 1e-38 132.3 0.0 1.8 2 0 0 2 2 2 1 Torsin AAA_2 PF07724.14 KFQ92914.1 - 0.0012 19.0 0.0 0.0024 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ResIII PF04851.15 KFQ92914.1 - 0.0024 17.9 0.0 0.0032 17.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.29 KFQ92914.1 - 0.055 13.9 0.0 0.089 13.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KFQ92914.1 - 0.088 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 KFQ92914.1 - 0.1 12.9 0.1 2.2 8.6 0.1 2.3 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KFQ92914.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 KFQ92914.1 - 0.17 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pept_tRNA_hydro PF01195.19 KFQ92915.1 - 3e-26 92.4 0.0 3.2e-26 92.3 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Glyco_transf_25 PF01755.17 KFQ92916.1 - 2.8e-29 102.4 0.0 3.2e-27 95.7 0.0 2.9 2 1 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_tranf_2_4 PF13704.6 KFQ92916.1 - 7.3e-08 32.8 0.2 1.9e-07 31.5 0.2 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Anp1 PF03452.14 KFQ92916.1 - 0.0094 15.4 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Anp1 Urm1 PF09138.11 KFQ92917.1 - 1e-37 128.4 0.0 1.1e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KFQ92917.1 - 0.00099 19.7 0.0 0.0012 19.5 0.0 1.1 1 0 0 1 1 1 1 ThiS family AMP-binding PF00501.28 KFQ92918.1 - 1.7e-70 237.8 0.0 2e-70 237.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFQ92918.1 - 0.00065 20.6 0.0 0.0012 19.8 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Coq4 PF05019.13 KFQ92919.1 - 4.7e-94 313.8 0.0 5.4e-94 313.7 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Rnk_N PF14760.6 KFQ92919.1 - 0.078 13.5 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 Rnk N-terminus LAB_N PF07578.11 KFQ92919.1 - 0.17 12.0 0.0 0.49 10.5 0.0 1.7 2 0 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain TruB_N PF01509.18 KFQ92920.1 - 9.8e-24 84.4 0.0 1.4e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KFQ92920.1 - 0.0055 16.8 0.2 0.015 15.4 0.1 1.9 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain Swi5 PF07061.11 KFQ92921.1 - 3.7e-24 84.6 1.6 4.3e-24 84.4 1.6 1.0 1 0 0 1 1 1 1 Swi5 APG6_N PF17675.1 KFQ92921.1 - 0.005 17.4 1.6 0.0061 17.1 1.6 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region ZapB PF06005.12 KFQ92921.1 - 0.0086 16.5 5.9 0.015 15.7 5.9 1.5 1 1 0 1 1 1 1 Cell division protein ZapB BLOC1_2 PF10046.9 KFQ92921.1 - 0.018 15.4 0.3 0.024 14.9 0.3 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 E2F_CC-MB PF16421.5 KFQ92921.1 - 0.051 13.9 0.4 0.058 13.8 0.4 1.1 1 0 0 1 1 1 0 E2F transcription factor CC-MB domain LINES_C PF14695.6 KFQ92921.1 - 0.06 12.8 1.2 3.8 7.0 0.1 2.5 3 0 0 3 3 3 0 Lines C-terminus HTH_38 PF13936.6 KFQ92921.1 - 0.072 12.9 0.6 2.2 8.1 0.1 2.2 1 1 1 2 2 2 0 Helix-turn-helix domain DUF5338 PF17273.2 KFQ92921.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5338) DivIC PF04977.15 KFQ92921.1 - 0.85 9.4 4.4 1.7 8.5 4.4 1.6 1 1 0 1 1 1 0 Septum formation initiator zf-C2H2_jaz PF12171.8 KFQ92922.1 - 8.6e-05 22.7 0.5 8.6e-05 22.7 0.5 4.8 4 1 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFQ92922.1 - 0.0015 18.8 29.3 0.0026 18.1 7.2 4.5 4 0 0 4 4 4 3 Zinc-finger of C2H2 type AKAP95 PF04988.12 KFQ92922.1 - 0.009 16.3 14.3 0.009 16.3 10.2 2.2 2 0 0 2 2 2 1 A-kinase anchoring protein 95 (AKAP95) Myc_N PF01056.18 KFQ92922.1 - 0.012 15.5 2.4 0.012 15.5 2.4 2.0 2 1 0 2 2 2 0 Myc amino-terminal region zf-C2H2_2 PF12756.7 KFQ92922.1 - 0.03 14.7 0.8 0.03 14.7 0.8 4.2 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFQ92922.1 - 0.056 14.3 1.1 0.056 14.3 1.1 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFQ92922.1 - 1.7 9.2 31.0 0.057 13.9 2.6 4.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type THAP PF05485.12 KFQ92922.1 - 3.7 8.5 11.8 0.52 11.3 7.1 2.1 2 0 0 2 2 2 0 THAP domain UPF0184 PF03670.13 KFQ92923.1 - 2.3e-24 85.6 4.2 2.6e-24 85.4 4.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0184) NYD-SP28 PF14772.6 KFQ92923.1 - 0.0024 17.9 2.9 0.0032 17.5 2.9 1.1 1 0 0 1 1 1 1 Sperm tail PhaP_Bmeg PF09602.10 KFQ92923.1 - 0.0026 17.7 0.5 0.003 17.5 0.5 1.0 1 0 0 1 1 1 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) EzrA PF06160.12 KFQ92923.1 - 0.0038 15.5 1.2 0.0041 15.4 1.2 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA GST_N_3 PF13417.6 KFQ92924.1 - 1e-12 48.3 0.5 1.2e-11 44.9 0.1 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 KFQ92924.1 - 3e-10 40.2 0.1 7.3e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.6 KFQ92924.1 - 2e-09 37.6 0.1 1.1e-08 35.2 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFQ92924.1 - 2.3e-06 27.5 0.0 4.4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KFQ92924.1 - 6.7e-05 23.6 0.0 0.00018 22.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N PF02798.20 KFQ92924.1 - 0.00032 21.0 0.0 0.00075 19.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFQ92924.1 - 0.00051 20.2 0.1 0.0011 19.2 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFQ92924.1 - 0.0029 17.7 0.0 0.0072 16.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Urocanase PF01175.18 KFQ92924.1 - 0.026 14.2 0.1 0.21 11.2 0.0 2.1 2 1 0 2 2 2 0 Urocanase Rossmann-like domain SNARE_assoc PF09335.11 KFQ92924.1 - 0.06 13.8 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 SNARE associated Golgi protein DUF668 PF05003.12 KFQ92924.1 - 0.091 13.2 0.0 0.34 11.4 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF668) GLE1 PF07817.13 KFQ92925.1 - 8.9e-89 297.0 0.0 1.6e-88 296.1 0.0 1.5 1 0 0 1 1 1 1 GLE1-like protein DUF4004 PF13171.6 KFQ92925.1 - 0.11 12.7 7.7 0.98 9.6 3.3 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF4004) WD40 PF00400.32 KFQ92926.1 - 2.1e-14 53.7 7.5 0.55 11.2 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ92926.1 - 3.1e-06 27.4 0.1 0.75 10.1 0.0 4.9 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Imm71 PF15602.6 KFQ92926.1 - 0.048 13.7 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 71 NAP PF00956.18 KFQ92927.1 - 1.3e-37 129.5 14.4 9.1e-34 116.9 5.3 3.1 2 1 1 3 3 3 2 Nucleosome assembly protein (NAP) Phage_Mu_Gam PF07352.12 KFQ92927.1 - 0.0032 17.4 2.6 0.0069 16.3 2.6 1.6 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein Mst1_SARAH PF11629.8 KFQ92927.1 - 0.064 13.4 0.8 0.17 12.0 0.8 1.7 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 ZapB PF06005.12 KFQ92927.1 - 2 8.9 9.9 0.12 12.9 4.4 1.8 2 0 0 2 2 2 0 Cell division protein ZapB Nore1-SARAH PF16517.5 KFQ92927.1 - 3.7 7.5 8.6 0.13 12.2 1.3 2.5 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Pkinase PF00069.25 KFQ92928.1 - 3.2e-58 197.2 0.0 5.4e-58 196.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ92928.1 - 4.7e-34 117.8 0.0 7.8e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 KFQ92928.1 - 4.4e-33 113.2 13.5 1.7e-16 60.0 4.3 2.3 2 0 0 2 2 2 2 Hr1 repeat Kinase-like PF14531.6 KFQ92928.1 - 1.2e-05 24.8 0.0 2.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Uds1 PF15456.6 KFQ92928.1 - 0.00015 22.0 6.6 0.012 15.8 1.5 2.3 2 0 0 2 2 2 2 Up-regulated During Septation PL48 PF15903.5 KFQ92928.1 - 0.027 13.5 1.6 4 6.3 0.1 2.2 2 0 0 2 2 2 0 Filopodia upregulated, FAM65 DHHC PF01529.20 KFQ92929.1 - 2e-30 105.6 14.4 3.4e-30 104.9 12.7 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Baculo_11_kDa PF06143.11 KFQ92929.1 - 0.021 14.4 0.3 0.021 14.4 0.3 2.2 2 0 0 2 2 2 0 Baculovirus 11 kDa family UL42 PF17638.2 KFQ92929.1 - 1.2 9.2 3.7 0.78 9.7 1.3 1.9 2 0 0 2 2 2 0 HCMV UL42 DUF4713 PF15831.5 KFQ92929.1 - 2.7 8.5 9.5 0.13 12.7 2.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4713) Arm PF00514.23 KFQ92930.1 - 1.5e-09 37.6 0.2 1.7 8.8 0.0 6.7 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat DUF3361 PF11841.8 KFQ92930.1 - 0.0088 16.0 2.1 2.3 8.1 0.8 3.5 3 1 0 3 3 3 1 Domain of unknown function (DUF3361) zf-CCCH_6 PF18585.1 KFQ92930.1 - 0.0091 15.9 0.2 2.5 8.1 0.0 3.9 3 0 0 3 3 3 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 HEAT_EZ PF13513.6 KFQ92930.1 - 0.019 15.4 0.0 0.14 12.7 0.0 2.6 3 0 0 3 3 3 0 HEAT-like repeat SWC7 PF17330.2 KFQ92930.1 - 0.055 13.5 0.6 0.24 11.5 0.1 2.3 2 0 0 2 2 2 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 CC190 PF15768.5 KFQ92930.1 - 0.096 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 LRR_8 PF13855.6 KFQ92930.1 - 0.1 12.4 8.9 3.1 7.6 0.3 4.0 4 0 0 4 4 4 0 Leucine rich repeat LRR_4 PF12799.7 KFQ92930.1 - 0.13 12.7 12.4 2 8.9 0.8 5.1 2 2 4 6 6 6 0 Leucine Rich repeats (2 copies) Lentiviral_Tat PF02998.14 KFQ92930.1 - 0.15 12.1 0.3 0.5 10.4 0.3 1.9 1 0 0 1 1 1 0 Lentiviral Tat protein LRR_1 PF00560.33 KFQ92930.1 - 0.36 11.5 6.4 40 5.3 0.1 5.7 5 0 0 5 5 5 0 Leucine Rich Repeat RabGAP-TBC PF00566.18 KFQ92931.1 - 3.2e-36 125.0 7.9 8.6e-34 117.1 2.3 2.7 2 1 0 2 2 2 2 Rab-GTPase-TBC domain TFIID_20kDa PF03847.13 KFQ92931.1 - 0.021 15.3 0.5 0.069 13.7 0.1 2.2 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Endonuclease_NS PF01223.23 KFQ92932.1 - 3.6e-65 219.9 0.0 4.1e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 KFQ92932.1 - 0.21 11.7 2.0 0.56 10.3 2.0 1.7 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease Methyltrn_RNA_3 PF02598.17 KFQ92933.1 - 1.2e-108 363.0 0.0 1.4e-108 362.8 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.19 KFQ92933.1 - 0.11 12.7 0.0 2.7 8.2 0.0 2.3 2 0 0 2 2 2 0 SpoU rRNA Methylase family Aminotran_1_2 PF00155.21 KFQ92934.1 - 2.2e-57 194.9 0.0 2.5e-57 194.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KFQ92934.1 - 0.0055 16.0 0.0 0.0098 15.2 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KFQ92934.1 - 0.01 14.4 0.0 0.029 12.9 0.0 1.7 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Pannexin_like PF12534.8 KFQ92935.1 - 4.2e-145 483.2 5.0 5.5e-145 482.9 5.0 1.1 1 0 0 1 1 1 1 Pannexin-like TM region of LRRC8 LRR_8 PF13855.6 KFQ92935.1 - 2.4e-30 104.1 40.6 8.5e-10 38.3 2.5 7.3 5 2 1 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 KFQ92935.1 - 9.9e-28 95.8 49.7 1.3e-06 28.6 1.1 9.6 6 3 2 9 9 9 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFQ92935.1 - 3.2e-11 43.3 0.5 5.5e-06 26.4 0.8 3.9 1 1 3 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFQ92935.1 - 4.2e-08 32.9 17.9 6.8e-05 22.4 1.5 3.6 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 KFQ92935.1 - 0.04 14.0 0.3 0.04 14.0 0.3 8.4 9 0 0 9 9 9 0 Leucine Rich repeat PhyH PF05721.13 KFQ92936.1 - 9.3e-63 212.3 0.0 1.2e-62 212.0 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Ycf70 PF17382.2 KFQ92937.1 - 5 7.6 5.3 3.5 8.1 1.1 2.9 2 0 0 2 2 2 0 Uncharacterized Ycf70-like Nup188 PF10487.9 KFQ92938.1 - 3e-231 770.1 0.3 3e-231 770.1 0.3 1.6 2 0 0 2 2 2 1 Nucleoporin subcomplex protein binding to Pom34 BAR PF03114.18 KFQ92939.1 - 7.8e-67 225.4 1.7 1.5e-66 224.5 1.7 1.5 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 KFQ92939.1 - 5.2e-11 42.2 0.1 1.1e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFQ92939.1 - 1.7e-06 27.5 0.0 3.2e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFQ92939.1 - 1.9e-06 27.4 0.0 3.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.9 KFQ92939.1 - 9e-06 25.0 0.2 1.5e-05 24.3 0.0 1.4 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 KFQ92939.1 - 0.00014 21.6 0.5 0.36 10.5 1.3 2.2 1 1 1 2 2 2 2 BAR domain of APPL family Miga PF10265.9 KFQ92940.1 - 2.1e-229 763.0 0.3 2.4e-229 762.8 0.3 1.0 1 0 0 1 1 1 1 Mitoguardin DUF3824 PF12868.7 KFQ92940.1 - 0.15 12.8 0.2 0.36 11.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) PAP2 PF01569.21 KFQ92941.1 - 8.6e-18 64.4 5.8 1.6e-17 63.5 5.8 1.4 1 0 0 1 1 1 1 PAP2 superfamily UbiA PF01040.18 KFQ92941.1 - 0.0072 15.6 8.8 0.0072 15.6 8.8 2.0 2 0 0 2 2 2 1 UbiA prenyltransferase family WTF PF03303.13 KFQ92941.1 - 0.078 12.7 0.7 0.1 12.3 0.7 1.2 1 0 0 1 1 1 0 WTF protein Phage_holin_3_1 PF05106.12 KFQ92941.1 - 0.089 13.2 0.4 0.17 12.4 0.4 1.4 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) DUF212 PF02681.14 KFQ92941.1 - 0.12 12.6 0.8 1.7 8.8 0.2 2.2 1 1 1 2 2 2 0 Divergent PAP2 family PSI_PsaJ PF01701.18 KFQ92941.1 - 0.34 11.5 5.7 3.8 8.1 0.1 3.2 3 0 0 3 3 3 0 Photosystem I reaction centre subunit IX / PsaJ Carn_acyltransf PF00755.20 KFQ92942.1 - 2.2e-206 687.0 0.0 2.5e-206 686.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase PTPA PF03095.15 KFQ92943.1 - 1.3e-122 409.0 0.0 1.6e-122 408.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Methyltransf_PK PF05891.12 KFQ92945.1 - 7e-93 310.1 0.0 8e-93 309.9 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KFQ92945.1 - 8.6e-13 48.8 0.0 2.6e-12 47.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFQ92945.1 - 6.4e-11 42.8 0.0 1.1e-10 42.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFQ92945.1 - 2.1e-09 38.0 0.0 3.8e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KFQ92945.1 - 3.7e-06 26.4 0.0 7.3e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 KFQ92945.1 - 4.4e-05 23.3 0.0 6.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFQ92945.1 - 7.2e-05 22.2 0.0 9.4e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KFQ92945.1 - 0.021 14.4 0.0 0.041 13.4 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Dioxygenase_N PF04444.14 KFQ92945.1 - 0.09 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Catechol dioxygenase N terminus DREV PF05219.12 KFQ92945.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_29 PF03141.16 KFQ92945.1 - 0.16 10.4 0.0 0.23 9.9 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ank_4 PF13637.6 KFQ92946.1 - 2.2e-21 75.9 1.1 1.4e-05 25.5 0.0 6.0 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 KFQ92946.1 - 4.9e-18 64.7 1.9 7.3e-07 29.4 0.0 5.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KFQ92946.1 - 3.5e-16 59.0 2.2 2e-07 31.2 0.1 5.2 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFQ92946.1 - 1.4e-15 57.7 0.1 9e-07 29.4 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFQ92946.1 - 4.2e-15 54.3 1.0 2.6e-06 27.3 0.0 6.7 7 0 0 7 7 7 2 Ankyrin repeat SOCS_box PF07525.16 KFQ92946.1 - 5.6e-12 45.8 7.1 1.1e-11 44.9 2.2 2.8 2 0 0 2 2 2 1 SOCS box N_methyl PF07963.12 KFQ92946.1 - 0.15 11.6 0.1 0.35 10.5 0.1 1.6 1 0 0 1 1 1 0 Prokaryotic N-terminal methylation motif Homeodomain PF00046.29 KFQ92947.1 - 2.9e-23 81.5 6.9 5.7e-23 80.5 6.9 1.5 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 KFQ92947.1 - 3.7e-08 32.9 0.1 9.1e-08 31.7 0.1 1.7 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 KFQ92947.1 - 0.00029 20.7 0.1 0.00029 20.7 0.1 1.8 2 0 0 2 2 2 1 Homeobox KN domain MAPEG PF01124.18 KFQ92948.1 - 1.9e-21 76.3 0.1 2.2e-21 76.1 0.1 1.0 1 0 0 1 1 1 1 MAPEG family Torsin PF06309.11 KFQ92949.1 - 2.1e-43 147.4 0.1 3.4e-43 146.8 0.1 1.3 1 0 0 1 1 1 1 Torsin Torsin PF06309.11 KFQ92950.1 - 4e-43 146.5 0.2 9.2e-43 145.4 0.1 1.7 2 0 0 2 2 2 1 Torsin Viral_helicase1 PF01443.18 KFQ92950.1 - 0.0013 18.6 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA PF00004.29 KFQ92950.1 - 0.0065 16.9 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFQ92950.1 - 0.013 15.7 0.0 0.52 10.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain Torsin PF06309.11 KFQ92951.1 - 1.1e-47 161.3 0.4 1.8e-47 160.6 0.4 1.4 1 0 0 1 1 1 1 Torsin AAA PF00004.29 KFQ92951.1 - 0.0032 17.9 0.0 0.0056 17.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFQ92951.1 - 0.036 14.1 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFQ92951.1 - 0.04 14.2 0.1 6.1 7.1 0.0 2.3 1 1 1 2 2 2 0 AAA domain Hep_59 PF07052.11 KFQ92952.1 - 2.2e-10 41.2 11.0 2.2e-09 38.0 0.6 3.4 4 0 0 4 4 4 2 Hepatocellular carcinoma-associated antigen 59 DUF2570 PF10828.8 KFQ92952.1 - 0.067 13.0 0.0 0.067 13.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2570) Folate_carrier PF01770.18 KFQ92952.1 - 0.16 10.7 0.8 0.26 10.0 0.8 1.3 1 0 0 1 1 1 0 Reduced folate carrier UCH PF00443.29 KFQ92953.1 - 1.9e-61 207.8 0.0 8.3e-61 205.7 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KFQ92953.1 - 5e-27 94.4 1.5 1e-15 58.1 0.0 2.9 3 0 0 3 3 3 2 DUSP domain UCH_1 PF13423.6 KFQ92953.1 - 1.8e-18 67.2 0.4 7.1e-16 58.7 0.0 4.1 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFQ92953.1 - 3.7e-16 59.2 5.2 3.7e-16 59.2 5.2 2.8 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein FCH PF00611.23 KFQ92954.1 - 1.3e-18 67.1 2.2 1.3e-18 67.1 2.2 3.3 4 1 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 KFQ92954.1 - 6.7e-10 38.7 0.2 1.6e-09 37.5 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFQ92954.1 - 1.5e-09 37.3 0.1 3.5e-09 36.1 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFQ92954.1 - 4.2e-06 26.3 0.1 9.7e-06 25.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFQ92954.1 - 0.00014 22.0 0.2 0.00029 21.0 0.2 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain Lzipper-MIP1 PF14389.6 KFQ92954.1 - 0.00026 21.2 0.6 0.00087 19.5 0.6 1.9 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 HR1 PF02185.16 KFQ92954.1 - 0.00029 20.9 0.2 0.00029 20.9 0.2 3.1 4 0 0 4 4 4 1 Hr1 repeat Laminin_II PF06009.12 KFQ92954.1 - 0.0041 17.1 6.6 0.3 11.1 0.3 3.0 2 1 0 2 2 2 2 Laminin Domain II SH3_16 PF18348.1 KFQ92954.1 - 0.12 12.2 0.1 0.31 10.9 0.1 1.7 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain Spectrin PF00435.21 KFQ92954.1 - 0.16 12.5 21.3 0.069 13.7 1.7 4.1 2 1 1 3 3 3 0 Spectrin repeat DUF1664 PF07889.12 KFQ92954.1 - 4.9 7.2 14.1 2.5 8.1 1.4 3.6 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Lung_7-TM_R PF06814.13 KFQ92955.1 - 7.6e-94 314.3 9.6 1e-93 313.8 9.6 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF4462 PF14692.6 KFQ92956.1 - 0.21 11.1 0.5 0.3 10.6 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) EF-hand_7 PF13499.6 KFQ92957.1 - 1.9e-25 89.1 4.1 2.5e-18 66.3 0.3 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KFQ92957.1 - 5.8e-24 81.8 5.2 2.7e-07 29.7 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KFQ92957.1 - 6.8e-23 78.6 3.5 8.5e-06 25.3 0.1 4.7 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 KFQ92957.1 - 1.6e-17 62.1 4.9 4.8e-05 22.7 0.4 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KFQ92957.1 - 3.3e-13 49.2 4.4 0.0001 22.1 0.3 3.6 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFQ92957.1 - 3.8e-05 24.0 0.8 0.041 14.2 0.2 3.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFQ92957.1 - 0.00041 20.3 2.4 0.72 9.8 0.1 3.1 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFQ92957.1 - 0.00054 20.2 0.1 0.036 14.4 0.0 3.0 2 1 1 3 3 3 1 EF-hand domain EF-hand_3 PF09069.11 KFQ92957.1 - 0.0055 17.1 0.1 0.037 14.5 0.0 1.9 2 0 0 2 2 2 1 EF-hand Caleosin PF05042.13 KFQ92957.1 - 0.0076 16.2 1.6 8.1 6.3 0.0 3.1 1 1 2 3 3 3 1 Caleosin related protein EF-hand_14 PF17959.1 KFQ92957.1 - 0.081 13.3 0.1 1.7 9.1 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain DUF1707 PF08044.11 KFQ92957.1 - 0.095 12.8 0.1 7.9 6.6 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1707) DUF1708 PF08101.11 KFQ92957.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) S10_plectin PF03501.15 KFQ92957.1 - 0.17 12.0 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain EF-hand_2 PF09068.11 KFQ92957.1 - 0.19 11.9 0.0 2.7 8.2 0.0 2.2 2 0 0 2 2 2 0 EF hand KH_1 PF00013.29 KFQ92958.1 - 1.2e-69 230.1 17.2 3.1e-19 68.6 0.3 4.2 4 0 0 4 4 4 4 KH domain KH_2 PF07650.17 KFQ92958.1 - 9.8e-22 76.6 9.9 1.3e-05 24.9 0.0 4.4 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 KFQ92958.1 - 1.7e-12 47.0 8.4 0.025 14.4 0.1 4.3 4 0 0 4 4 4 4 KH domain DUF1897 PF09005.10 KFQ92958.1 - 0.0006 19.2 8.9 0.0014 18.0 8.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1897) KH_5 PF13184.6 KFQ92958.1 - 0.0042 17.2 10.3 10 6.3 0.1 4.4 4 0 0 4 4 4 3 NusA-like KH domain CBM_3 PF00942.18 KFQ92959.1 - 0.0038 17.6 0.2 0.0053 17.2 0.2 1.2 1 0 0 1 1 1 1 Cellulose binding domain zf-H2C2_2 PF13465.6 KFQ92960.1 - 8.7e-12 44.9 6.3 1.7e-05 25.0 0.6 2.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ92960.1 - 6.8e-06 26.2 2.9 6.8e-06 26.2 2.9 2.3 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ92960.1 - 1e-05 25.9 2.1 1e-05 25.9 2.1 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ92960.1 - 0.0038 17.5 0.1 0.0054 17.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFQ92960.1 - 0.0048 17.2 0.4 0.0091 16.4 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFQ92960.1 - 0.01 15.6 1.4 0.01 15.6 1.4 2.9 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-BED PF02892.15 KFQ92960.1 - 0.017 15.1 0.7 0.019 15.0 0.7 1.2 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_2 PF12756.7 KFQ92960.1 - 0.023 15.0 0.1 0.024 15.0 0.1 1.1 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf_C2H2_6 PF18450.1 KFQ92960.1 - 0.031 14.0 0.8 0.047 13.4 0.8 1.3 1 0 0 1 1 1 0 Zinc Finger domain DUF629 PF04780.12 KFQ92960.1 - 0.035 12.7 0.1 0.035 12.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF629) KH_6 PF15985.5 KFQ92961.1 - 8e-14 51.7 0.0 1.7e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 KFQ92961.1 - 5.4e-07 29.3 0.1 9.8e-07 28.5 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Pkinase_Tyr PF07714.17 KFQ92962.1 - 6e-99 330.5 0.0 8.5e-99 330.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ92962.1 - 5.1e-48 163.7 0.0 8.5e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain F_actin_bind PF08919.10 KFQ92962.1 - 7.4e-30 103.3 0.2 1.6e-29 102.2 0.2 1.6 1 0 0 1 1 1 1 F-actin binding SH2 PF00017.24 KFQ92962.1 - 1e-23 83.2 0.2 2.7e-23 81.9 0.2 1.8 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFQ92962.1 - 1.6e-12 46.8 0.0 2.8e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFQ92962.1 - 1.1e-08 34.7 0.0 2.2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFQ92962.1 - 1.7e-07 30.8 0.0 3.4e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFQ92962.1 - 5.8e-05 23.3 0.2 0.00016 21.8 0.2 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain Haspin_kinase PF12330.8 KFQ92962.1 - 0.0011 18.1 0.1 0.002 17.1 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain SH3_6 PF12913.7 KFQ92962.1 - 0.15 11.6 0.0 0.39 10.3 0.0 1.7 1 0 0 1 1 1 0 SH3 domain (SH3b1 type) RFamide_26RFa PF11109.8 KFQ92963.1 - 1.4e-32 113.0 0.3 1.6e-32 112.8 0.3 1.0 1 0 0 1 1 1 1 Orexigenic neuropeptide Qrfp/P518 Fibrinogen_C PF00147.18 KFQ92964.1 - 3e-76 256.1 5.7 4.1e-76 255.7 5.7 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain ATG16 PF08614.11 KFQ92964.1 - 0.033 14.4 0.9 0.049 13.9 0.9 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) CFC PF09443.10 KFQ92964.1 - 0.2 11.5 1.8 0.4 10.6 1.8 1.5 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) CENP-F_leu_zip PF10473.9 KFQ92964.1 - 0.27 11.3 1.1 0.55 10.2 1.1 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Snapin_Pallidin PF14712.6 KFQ92964.1 - 0.33 11.4 4.9 0.47 10.9 0.6 2.3 2 0 0 2 2 2 0 Snapin/Pallidin Laminin_EGF PF00053.24 KFQ92965.1 - 3.8e-79 260.6 204.9 5.6e-12 45.6 10.9 12.1 11 0 0 11 11 11 11 Laminin EGF domain Laminin_N PF00055.17 KFQ92965.1 - 3.3e-77 259.2 0.0 3.3e-77 259.2 0.0 2.7 3 0 0 3 3 3 1 Laminin N-terminal (Domain VI) Laminin_B PF00052.18 KFQ92965.1 - 1.7e-28 99.2 0.1 1.7e-28 99.2 0.1 1.7 2 0 0 2 2 2 1 Laminin B (Domain IV) APG17 PF04108.12 KFQ92965.1 - 0.14 11.3 6.2 0.26 10.4 6.2 1.4 1 0 0 1 1 1 0 Autophagy protein Apg17 EF-hand_7 PF13499.6 KFQ92966.1 - 0.0013 19.1 0.0 0.0019 18.6 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFQ92966.1 - 0.0037 16.7 3.4 0.14 11.8 0.7 2.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFQ92966.1 - 0.0049 16.7 0.1 0.079 12.9 0.1 2.5 3 0 0 3 3 3 1 EF-hand domain UPF0154 PF03672.13 KFQ92966.1 - 0.019 15.0 1.2 0.03 14.3 1.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) TOPRIM_C PF16898.5 KFQ92966.1 - 0.077 13.3 0.2 0.1 12.9 0.2 1.1 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM PAP2 PF01569.21 KFQ92969.1 - 4.6e-14 52.4 3.3 7e-14 51.8 3.3 1.2 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KFQ92969.1 - 0.00091 19.0 7.5 0.0026 17.5 7.5 1.8 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KFQ92969.1 - 0.027 15.0 0.6 0.027 15.0 0.6 1.6 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Zip PF02535.22 KFQ92969.1 - 2.3 7.4 7.3 25 3.9 7.3 2.0 1 1 0 1 1 1 0 ZIP Zinc transporter BAT2_N PF07001.11 KFQ92970.1 - 2.9e-67 226.9 10.3 2.9e-67 226.9 10.3 6.3 5 1 0 6 6 6 1 BAT2 N-terminus PMT PF02366.18 KFQ92971.1 - 9.6e-90 300.4 22.6 9.6e-90 300.4 22.6 2.1 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KFQ92971.1 - 5.6e-53 179.5 11.3 5.6e-53 179.5 11.3 2.9 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KFQ92971.1 - 2.6e-12 47.0 0.0 4.9e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 MIR domain HPP PF04982.13 KFQ92971.1 - 2.3 8.4 10.3 0.094 12.9 0.4 3.5 4 1 0 4 4 4 0 HPP family PRK PF00485.18 KFQ92972.1 - 2.5e-45 154.6 0.9 2.9e-45 154.4 0.9 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CD225 PF04505.12 KFQ92973.1 - 3.7e-21 75.0 0.8 4.6e-21 74.7 0.8 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF4190 PF13828.6 KFQ92973.1 - 0.12 12.1 0.1 0.12 12.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) DUF4328 PF14219.6 KFQ92973.1 - 1.3 8.5 5.9 2.9 7.4 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4328) RasGEF PF00617.19 KFQ92974.1 - 6e-53 179.7 0.7 2.4e-52 177.7 0.3 2.2 1 1 1 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KFQ92974.1 - 4.9e-07 29.9 0.4 4.9e-07 29.9 0.4 3.2 4 0 0 4 4 4 1 RasGEF N-terminal motif Med27 PF11571.8 KFQ92975.1 - 9.4e-28 96.4 0.2 1.8e-27 95.5 0.2 1.5 1 0 0 1 1 1 1 Mediator complex subunit 27 Laminin_N PF00055.17 KFQ92976.1 - 1.4e-49 168.8 0.0 1.4e-49 168.8 0.0 3.3 3 1 1 4 4 4 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 KFQ92976.1 - 3.3e-21 75.2 68.1 3.7e-09 36.6 14.0 4.7 3 1 1 4 4 4 3 Laminin EGF domain EGF PF00008.27 KFQ92976.1 - 0.0017 18.6 7.6 0.0017 18.6 7.6 5.6 4 2 2 6 6 6 2 EGF-like domain BNR PF02012.20 KFQ92976.1 - 0.012 15.5 1.1 1.5 9.2 0.0 3.2 2 0 0 2 2 2 0 BNR/Asp-box repeat F5_F8_type_C PF00754.25 KFQ92976.1 - 0.21 11.7 0.1 0.49 10.5 0.0 1.6 2 0 0 2 2 2 0 F5/8 type C domain AAA_11 PF13086.6 KFQ92977.1 - 1.7e-66 224.7 3.3 1.7e-66 224.7 3.3 3.5 4 0 0 4 4 3 1 AAA domain AAA_12 PF13087.6 KFQ92977.1 - 1e-54 185.2 0.8 4e-54 183.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain SEN1_N PF12726.7 KFQ92977.1 - 1.5e-13 50.0 3.3 6.4e-13 47.8 3.3 2.0 1 1 0 1 1 1 1 SEN1 N terminal AAA_19 PF13245.6 KFQ92977.1 - 2.4e-09 37.7 0.0 3.3e-08 34.0 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_30 PF13604.6 KFQ92977.1 - 2.5e-09 37.1 0.3 0.0025 17.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 KFQ92977.1 - 8.7e-06 25.6 3.7 0.56 9.9 0.0 4.2 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KFQ92977.1 - 0.0001 22.6 0.3 0.00058 20.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFQ92977.1 - 0.0015 18.9 0.0 0.005 17.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 KFQ92977.1 - 0.0019 18.3 0.3 0.01 15.8 0.1 2.5 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit DUF4164 PF13747.6 KFQ92977.1 - 0.0051 17.1 7.0 0.019 15.3 7.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) RNA_helicase PF00910.22 KFQ92977.1 - 0.052 13.9 0.3 0.46 10.9 0.0 2.8 3 0 0 3 3 2 0 RNA helicase Helicase_RecD PF05127.14 KFQ92977.1 - 0.062 13.1 0.1 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 Helicase efb-c PF12199.8 KFQ92977.1 - 0.64 10.1 2.7 1.6 8.8 0.2 2.9 3 0 0 3 3 3 0 Extracellular fibrinogen binding protein C terminal Cep57_CLD_2 PF14197.6 KFQ92977.1 - 0.86 9.7 5.3 2.9 8.0 5.3 2.0 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Myb_DNA-bind_6 PF13921.6 KFQ92978.1 - 8.8e-17 61.1 8.8 3.1e-14 53.0 0.8 3.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFQ92978.1 - 1.1e-14 54.3 15.4 1.3e-09 38.1 0.2 3.7 4 1 0 4 4 4 2 Myb-like DNA-binding domain WbqC PF08889.11 KFQ92978.1 - 0.0041 17.1 1.9 0.035 14.0 0.0 2.8 2 1 0 3 3 3 1 WbqC-like protein family Poxvirus_B22R_N PF13169.6 KFQ92978.1 - 0.03 14.8 0.6 0.03 14.8 0.6 2.9 2 1 0 3 3 3 0 Poxvirus B22R protein N-terminal MMTV_SAg PF01054.17 KFQ92978.1 - 0.044 13.3 1.8 0.098 12.2 1.8 1.6 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen rhaM PF05336.13 KFQ92978.1 - 3.2 7.8 7.5 0.27 11.3 1.9 2.1 2 2 0 2 2 2 0 L-rhamnose mutarotase Anophelin PF10731.9 KFQ92979.1 - 0.0078 16.0 0.3 0.013 15.4 0.3 1.4 1 0 0 1 1 1 1 Thrombin inhibitor from mosquito Homeodomain PF00046.29 KFQ92980.1 - 3.2e-21 74.9 2.6 3.5e-21 74.8 2.6 1.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ92980.1 - 0.009 15.9 0.4 0.015 15.2 0.1 1.5 2 0 0 2 2 2 1 Homeobox KN domain DEAD PF00270.29 KFQ92981.1 - 3.5e-45 153.9 0.0 7.4e-45 152.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFQ92981.1 - 5.9e-26 91.0 0.0 2.3e-25 89.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFQ92981.1 - 1.2e-14 54.3 0.1 2.4e-14 53.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KFQ92981.1 - 1.1e-06 28.8 0.0 2.3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFQ92981.1 - 0.00085 18.6 0.1 0.0046 16.2 0.0 2.0 1 1 1 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase FF PF01846.19 KFQ92981.1 - 0.0079 16.4 0.6 0.34 11.1 0.1 2.5 2 0 0 2 2 2 1 FF domain Helicase_C_2 PF13307.6 KFQ92981.1 - 0.021 15.0 0.1 0.043 14.0 0.1 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain SecA_DEAD PF07517.14 KFQ92981.1 - 0.11 11.7 0.1 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 SecA DEAD-like domain Med29 PF11568.8 KFQ92981.1 - 4.9 7.4 6.4 5 7.4 0.1 3.4 3 1 1 4 4 4 0 Mediator complex subunit 29 TFIIIC_delta PF12657.7 KFQ92982.1 - 1.7e-29 103.0 0.0 4.6e-28 98.4 0.0 2.4 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 KFQ92982.1 - 1.2e-09 38.0 1.9 1.2e-09 38.0 1.9 2.1 2 0 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex ADK PF00406.22 KFQ92983.1 - 0.0074 16.4 0.1 0.0091 16.1 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK PF00406.22 KFQ92984.1 - 2.1e-43 148.0 0.0 6.9e-24 84.7 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 KFQ92984.1 - 1.2e-22 80.8 0.0 7.7e-12 45.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KFQ92984.1 - 3.6e-14 53.4 0.0 5e-10 40.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KFQ92984.1 - 2.5e-13 50.4 0.0 4.9e-08 33.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Hydin_ADK PF17213.3 KFQ92984.1 - 1.1e-12 48.6 0.0 0.011 16.1 0.0 4.1 4 0 0 4 4 4 3 Hydin Adenylate kinase-like domain AAA PF00004.29 KFQ92984.1 - 3.8e-09 37.1 0.0 0.00069 20.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFQ92984.1 - 3.1e-06 27.0 0.0 0.089 12.5 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain KTI12 PF08433.10 KFQ92984.1 - 8.9e-06 25.3 0.0 0.015 14.8 0.0 2.4 2 0 0 2 2 2 2 Chromatin associated protein KTI12 AAA_16 PF13191.6 KFQ92984.1 - 9.2e-06 26.1 0.0 0.12 12.8 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KFQ92984.1 - 0.00019 21.7 0.1 0.54 10.5 0.0 2.8 3 1 0 3 3 2 2 AAA domain AAA_19 PF13245.6 KFQ92984.1 - 0.00024 21.5 0.0 0.0034 17.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KFQ92984.1 - 0.0004 19.8 0.0 0.37 10.1 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KFQ92984.1 - 0.00076 19.8 0.0 2.3 8.7 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 KFQ92984.1 - 0.0013 19.0 0.0 0.81 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFQ92984.1 - 0.0019 18.2 0.0 2.9 7.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KFQ92984.1 - 0.002 17.9 0.0 1.8 8.3 0.0 2.2 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_24 PF13479.6 KFQ92984.1 - 0.0029 17.4 0.0 0.83 9.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KFQ92984.1 - 0.003 18.1 0.0 2.1 8.9 0.0 2.4 2 1 0 2 2 2 1 ABC transporter Cytidylate_kin PF02224.18 KFQ92984.1 - 0.0047 16.7 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase Thymidylate_kin PF02223.17 KFQ92984.1 - 0.0083 15.8 0.0 4.5 6.9 0.0 3.2 3 0 0 3 3 3 1 Thymidylate kinase NACHT PF05729.12 KFQ92984.1 - 0.012 15.5 0.0 0.79 9.6 0.0 2.4 2 0 0 2 2 2 0 NACHT domain DUF3987 PF13148.6 KFQ92984.1 - 0.017 14.2 0.0 0.099 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Sigma54_activ_2 PF14532.6 KFQ92984.1 - 0.017 15.2 0.0 8 6.6 0.0 2.9 2 1 0 2 2 2 0 Sigma-54 interaction domain ResIII PF04851.15 KFQ92984.1 - 0.025 14.6 0.0 0.69 9.9 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Rad17 PF03215.15 KFQ92984.1 - 0.038 13.9 0.1 6.9 6.5 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_7 PF12775.7 KFQ92984.1 - 0.045 13.3 0.0 9.3 5.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 KFQ92984.1 - 0.053 13.1 0.0 4.2 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 KFQ92984.1 - 0.077 13.1 0.0 1.7 8.8 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase AAA_29 PF13555.6 KFQ92984.1 - 0.077 12.7 0.0 3.7 7.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain RIIa PF02197.17 KFQ92984.1 - 0.098 12.3 0.0 0.34 10.6 0.0 1.9 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit TIP49 PF06068.13 KFQ92984.1 - 0.1 11.8 0.0 4.6 6.3 0.0 2.4 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_11 PF13086.6 KFQ92984.1 - 0.11 12.3 0.0 4.1 7.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KFQ92984.1 - 0.12 11.6 0.0 12 5.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin dNK PF01712.19 KFQ92984.1 - 0.17 11.8 0.0 1.4 8.8 0.0 2.4 3 0 0 3 3 2 0 Deoxynucleoside kinase APS_kinase PF01583.20 KFQ92984.1 - 0.17 11.8 0.0 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase SPACA9 PF15120.6 KFQ92985.1 - 1.8e-79 265.2 1.4 2e-79 265.1 1.4 1.0 1 0 0 1 1 1 1 Sperm acrosome-associated protein 9 Allexi_40kDa PF05549.11 KFQ92985.1 - 0.0041 16.7 0.2 0.0052 16.3 0.2 1.3 1 0 0 1 1 1 1 Allexivirus 40kDa protein Binary_toxB_2 PF17475.2 KFQ92985.1 - 0.03 14.1 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA domain 2 Pox_MCEL PF03291.16 KFQ92985.1 - 0.087 11.9 0.3 5.6 6.0 0.0 2.0 1 1 1 2 2 2 0 mRNA capping enzyme zf-H2C2_2 PF13465.6 KFQ92986.1 - 5.5e-30 102.4 42.0 9.1e-08 32.2 2.0 7.1 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ92986.1 - 3.2e-29 99.7 45.9 1.2e-05 25.5 1.4 6.6 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ92986.1 - 2.4e-21 74.6 44.4 0.00032 21.3 1.2 6.6 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ92986.1 - 8.5e-15 54.6 27.1 0.0031 17.8 0.0 6.9 7 0 0 7 7 6 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFQ92986.1 - 1.8e-10 40.6 41.5 0.0024 17.8 2.8 6.5 6 0 0 6 6 6 6 C2H2-type zinc finger zf-met PF12874.7 KFQ92986.1 - 1e-08 35.3 33.3 0.0076 16.6 0.3 6.3 6 0 0 6 6 6 3 Zinc-finger of C2H2 type Ta0938 PF11494.8 KFQ92986.1 - 0.00018 21.7 0.7 0.57 10.5 0.0 2.7 2 1 1 3 3 3 2 Ta0938 zf-CHCC PF10276.9 KFQ92986.1 - 0.00078 19.5 9.7 0.44 10.6 0.3 4.5 4 0 0 4 4 4 2 Zinc-finger domain FYVE PF01363.21 KFQ92986.1 - 0.0023 18.1 26.1 0.082 13.1 9.3 3.8 1 1 3 4 4 4 2 FYVE zinc finger zf-AN1 PF01428.16 KFQ92986.1 - 0.0033 17.6 22.4 3.6 7.8 0.2 6.4 6 0 0 6 6 6 1 AN1-like Zinc finger zf-C2H2_3rep PF18868.1 KFQ92986.1 - 0.0041 17.8 20.2 1.2 9.9 1.9 5.1 1 1 2 3 3 3 1 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 KFQ92986.1 - 0.0089 16.1 23.9 2.5 8.3 0.3 5.2 3 2 2 6 6 6 3 Zinc ribbon domain zf_UBZ PF18439.1 KFQ92986.1 - 0.011 15.4 19.4 6.3 6.5 0.1 5.8 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger HNH_5 PF14279.6 KFQ92986.1 - 0.012 15.4 14.8 4.1 7.3 0.9 6.2 5 1 0 5 5 5 0 HNH endonuclease zf-BED PF02892.15 KFQ92986.1 - 0.021 14.8 34.3 0.21 11.6 7.3 5.7 4 1 2 6 6 6 0 BED zinc finger BolA PF01722.18 KFQ92986.1 - 0.026 14.8 7.3 4 7.8 2.1 3.5 2 2 0 2 2 2 0 BolA-like protein Prok-RING_1 PF14446.6 KFQ92986.1 - 0.026 14.4 16.5 8.6 6.4 0.1 6.0 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 HypA PF01155.19 KFQ92986.1 - 0.043 13.8 13.4 0.75 9.8 3.9 3.4 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_8 PF15909.5 KFQ92986.1 - 0.044 14.1 20.2 0.24 11.7 4.2 3.4 1 1 3 4 4 4 0 C2H2-type zinc ribbon zinc_ribbon_15 PF17032.5 KFQ92986.1 - 0.065 14.0 15.4 1 10.2 1.8 3.5 1 1 1 3 3 3 0 zinc-ribbon family XPA_N PF01286.18 KFQ92986.1 - 0.21 11.6 19.9 7.6 6.7 0.1 6.2 6 0 0 6 6 6 0 XPA protein N-terminal GAGA PF09237.11 KFQ92986.1 - 0.3 10.9 7.9 7.1 6.5 0.1 3.8 2 2 2 4 4 4 0 GAGA factor Sprouty PF05210.13 KFQ92986.1 - 0.32 11.4 12.0 4 7.9 0.4 2.9 2 1 0 2 2 2 0 Sprouty protein (Spry) zf-C2H2_2 PF12756.7 KFQ92986.1 - 0.69 10.3 28.7 3.3 8.1 1.0 6.1 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KFQ92986.1 - 1.6 8.5 28.1 8.2 6.3 0.1 6.3 6 0 0 6 6 6 0 zinc-finger C2H2-type zf-Di19 PF05605.12 KFQ92986.1 - 1.8 8.9 33.3 0.11 12.8 4.9 4.6 3 2 1 5 5 4 0 Drought induced 19 protein (Di19), zinc-binding PyrI_C PF02748.15 KFQ92986.1 - 2.1 8.3 18.1 1.5 8.7 0.1 5.5 5 1 1 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain HNH PF01844.23 KFQ92986.1 - 2.4 8.4 22.8 1.9 8.7 0.7 5.5 6 0 0 6 6 6 0 HNH endonuclease Zn_ribbon_SprT PF17283.2 KFQ92986.1 - 3.8 7.5 18.4 16 5.5 0.1 4.7 4 1 0 4 4 4 0 SprT-like zinc ribbon domain zinc-ribbons_6 PF07191.12 KFQ92986.1 - 4.2 7.4 19.6 11 6.0 1.1 4.7 1 1 2 4 4 4 0 zinc-ribbons zf-C2HC_2 PF13913.6 KFQ92986.1 - 7.4 6.6 26.9 1.7 8.7 1.0 5.5 6 0 0 6 6 5 0 zinc-finger of a C2HC-type DZR PF12773.7 KFQ92986.1 - 7.5 6.7 19.8 1.2e+04 -3.6 19.8 3.7 1 1 0 1 1 0 0 Double zinc ribbon ADK_lid PF05191.14 KFQ92986.1 - 8.8 6.4 14.4 50 4.0 0.8 4.2 1 1 3 4 4 4 0 Adenylate kinase, active site lid Mut7-C PF01927.16 KFQ92986.1 - 9.4 6.3 11.0 10 6.2 3.3 3.2 1 1 1 2 2 2 0 Mut7-C RNAse domain zf_C2H2_ZHX PF18387.1 KFQ92986.1 - 9.8 5.9 20.6 0.089 12.4 3.8 3.9 3 2 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain COesterase PF00135.28 KFQ92987.1 - 1.6e-151 505.7 0.0 2e-151 505.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFQ92987.1 - 3.2e-08 33.7 0.0 6.2e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFQ92987.1 - 0.00041 19.9 0.0 0.00073 19.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Tau95 PF09734.9 KFQ92988.1 - 6.4e-41 140.4 0.4 1.9e-40 138.9 0.4 1.8 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KFQ92988.1 - 5.7e-20 71.8 0.1 1.6e-19 70.4 0.1 1.8 1 0 0 1 1 1 1 Tau95 Triple barrel domain PTPRCAP PF15713.5 KFQ92988.1 - 0.1 12.9 3.4 0.18 12.1 3.4 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Glyco_transf_6 PF03414.13 KFQ92989.1 - 1.3e-142 474.4 0.1 1.4e-142 474.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 6 Glyco_tranf_2_4 PF13704.6 KFQ92989.1 - 0.17 12.4 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF4456 PF14644.6 KFQ92990.1 - 2.5e-61 207.0 8.7 2.7e-61 206.9 8.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4456) MutS_II PF05188.17 KFQ92991.1 - 0.036 14.3 0.4 0.074 13.3 0.4 1.6 1 0 0 1 1 1 0 MutS domain II CobU PF02283.16 KFQ92991.1 - 0.041 13.5 0.4 0.06 12.9 0.4 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF4455 PF14643.6 KFQ92992.1 - 9.4e-44 149.8 4.9 1e-43 149.7 4.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) HTH_WhiA PF02650.14 KFQ92992.1 - 0.048 14.0 0.1 0.23 11.8 0.0 2.2 1 1 1 2 2 2 0 WhiA C-terminal HTH domain Chal_sti_synt_N PF00195.19 KFQ92992.1 - 0.16 11.3 0.1 0.18 11.2 0.1 1.1 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain SURF6 PF04935.12 KFQ92993.1 - 1.2e-38 133.0 66.6 1.2e-38 133.0 66.6 2.1 2 0 0 2 2 2 2 Surfeit locus protein 6 Med22 PF06179.12 KFQ92994.1 - 3.9e-27 94.5 1.9 5.4e-27 94.1 1.9 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Ribosomal_L7Ae PF01248.26 KFQ92995.1 - 3.1e-24 84.5 0.3 1.5e-23 82.3 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SURF1 PF02104.15 KFQ92996.1 - 2.6e-43 148.3 0.0 3.1e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 SURF1 family SURF2 PF05477.11 KFQ92997.1 - 1.5e-85 286.7 7.9 1.7e-85 286.5 7.9 1.0 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) SURF4 PF02077.15 KFQ92998.1 - 6.5e-123 409.5 9.6 7.3e-123 409.4 9.6 1.0 1 0 0 1 1 1 1 SURF4 family SURF2 PF05477.11 KFQ92998.1 - 3.9e-38 131.5 0.0 4.2e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) DoxX PF07681.12 KFQ92998.1 - 0.03 14.9 0.2 0.03 14.9 0.2 3.5 4 1 1 5 5 5 0 DoxX Pkinase PF00069.25 KFQ92999.1 - 8.7e-32 110.5 0.6 9.2e-32 110.4 0.6 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ92999.1 - 6.1e-28 97.8 1.2 6.7e-28 97.7 1.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ92999.1 - 0.00037 19.9 0.3 0.00048 19.5 0.3 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFQ92999.1 - 0.014 14.8 0.1 0.016 14.5 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2004 PF09406.10 KFQ92999.1 - 0.17 12.2 1.5 0.65 10.3 1.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2004) FDX-ACB PF03147.14 KFQ93000.1 - 0.078 13.4 2.2 12 6.4 0.2 3.3 3 0 0 3 3 3 0 Ferredoxin-fold anticodon binding domain UME PF08064.13 KFQ93000.1 - 0.25 11.3 8.3 0.24 11.3 0.3 3.5 2 2 2 4 4 4 0 UME (NUC010) domain IFRD PF05004.13 KFQ93000.1 - 0.37 9.9 8.5 3 6.9 1.2 2.2 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) RNase_T PF00929.24 KFQ93001.1 - 2.2e-21 77.1 0.1 5.6e-21 75.8 0.0 1.7 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KFQ93001.1 - 3.2e-05 23.7 0.0 9.8e-05 22.1 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease DUF4678 PF15727.5 KFQ93001.1 - 0.033 13.5 1.3 0.051 12.8 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4678) DUF3987 PF13148.6 KFQ93001.1 - 8.2 5.3 7.4 1.7 7.5 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Reprolysin_3 PF13582.6 KFQ93002.1 - 8.7e-05 23.0 0.0 9.6e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like BetaGal_dom4_5 PF13364.6 KFQ93002.1 - 0.0075 16.8 0.0 0.0077 16.8 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Reprolysin_4 PF13583.6 KFQ93002.1 - 0.024 14.3 0.0 0.027 14.1 0.0 1.1 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like CUB PF00431.20 KFQ93003.1 - 0.011 16.0 0.1 0.031 14.6 0.1 1.7 2 0 0 2 2 2 0 CUB domain Cg6151-P PF10233.9 KFQ93004.1 - 9e-30 103.3 5.4 1.1e-29 103.0 5.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF4191 PF13829.6 KFQ93004.1 - 0.034 13.5 0.1 0.034 13.5 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) TMEM72 PF16054.5 KFQ93004.1 - 0.096 12.4 3.1 0.13 12.0 3.1 1.2 1 0 0 1 1 1 0 Transmembrane protein family 72 COPI_assoc PF08507.10 KFQ93004.1 - 0.81 9.7 5.6 2.1 8.4 5.6 1.8 1 1 0 1 1 1 0 COPI associated protein DUF3522 PF12036.8 KFQ93005.1 - 9.1e-59 198.9 7.3 1.1e-58 198.7 7.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) Oxidored_q5_N PF01059.17 KFQ93005.1 - 0.18 11.9 5.8 0.26 11.4 3.5 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus TSP_1 PF00090.19 KFQ93006.1 - 2.2e-22 79.0 106.3 1.4e-05 25.2 5.0 9.3 8 2 0 8 8 8 7 Thrombospondin type 1 domain ADAM_spacer1 PF05986.14 KFQ93006.1 - 2.9e-15 56.3 0.1 7.4e-15 55.0 0.1 1.7 1 1 0 1 1 1 1 ADAM-TS Spacer 1 PLAC PF08686.11 KFQ93006.1 - 6.7e-10 39.6 9.5 3.6e-09 37.2 9.5 2.5 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain FAM163 PF15069.6 KFQ93007.1 - 4.4e-65 219.1 0.0 4.9e-65 218.9 0.0 1.0 1 0 0 1 1 1 1 FAM163 family DUF4006 PF13179.6 KFQ93007.1 - 0.0074 16.2 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF4006) ECSCR PF15820.5 KFQ93007.1 - 0.09 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator PRIMA1 PF16101.5 KFQ93007.1 - 0.11 12.5 0.2 0.11 12.5 0.2 2.1 2 1 1 3 3 3 0 Proline-rich membrane anchor 1 HCV_NS4a PF01006.20 KFQ93007.1 - 2.6 7.8 5.2 3.4 7.5 3.2 2.0 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a RhoGEF PF00621.20 KFQ93008.1 - 2.1e-39 135.7 6.0 2.1e-39 135.7 6.0 2.3 3 0 0 3 3 2 1 RhoGEF domain SH3_2 PF07653.17 KFQ93008.1 - 7.2e-28 96.1 0.4 3e-14 52.4 0.1 3.6 3 0 0 3 3 3 2 Variant SH3 domain CAMSAP_CH PF11971.8 KFQ93008.1 - 3.9e-26 90.7 0.1 1.4e-25 88.9 0.1 2.1 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.31 KFQ93008.1 - 8.9e-22 77.3 1.2 5.1e-21 74.9 0.0 2.7 3 0 0 3 3 3 1 Calponin homology (CH) domain SH3_1 PF00018.28 KFQ93008.1 - 2e-21 75.3 0.6 3.3e-12 45.8 0.1 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KFQ93008.1 - 1.4e-19 69.7 0.5 2.8e-11 43.1 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH2 PF00017.24 KFQ93008.1 - 1e-16 60.7 0.2 3.5e-16 59.1 0.2 2.0 1 0 0 1 1 1 1 SH2 domain C1_1 PF00130.22 KFQ93008.1 - 8.8e-10 38.3 3.3 2e-09 37.2 3.3 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 KFQ93008.1 - 1.1e-08 35.5 1.9 2.1e-08 34.6 0.9 2.0 2 0 0 2 2 1 1 PH domain CDC24 PF06395.11 KFQ93008.1 - 0.0074 16.5 0.0 0.021 15.1 0.0 1.8 1 0 0 1 1 1 1 CDC24 Calponin PH_10 PF15411.6 KFQ93008.1 - 0.012 15.8 2.2 0.045 14.0 0.1 2.6 1 1 1 2 2 2 0 Pleckstrin homology domain Prok-RING_1 PF14446.6 KFQ93008.1 - 0.016 15.1 2.8 0.049 13.6 2.8 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 KFQ93008.1 - 0.037 13.6 0.3 0.11 12.1 0.3 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type C1_2 PF03107.16 KFQ93008.1 - 0.17 12.2 8.1 0.045 14.1 4.1 2.1 2 0 0 2 2 2 0 C1 domain SH3_3 PF08239.11 KFQ93008.1 - 0.29 11.4 4.3 3.5 8.0 2.2 2.8 3 0 0 3 3 3 0 Bacterial SH3 domain CotJB PF12652.7 KFQ93008.1 - 1.5 9.1 6.9 1.3 9.3 0.1 3.0 3 0 0 3 3 2 0 CotJB protein Bromodomain PF00439.25 KFQ93009.1 - 4.6e-42 142.0 5.3 2.3e-21 75.7 0.3 2.4 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KFQ93009.1 - 3.4e-29 100.8 0.1 3.4e-29 100.8 0.1 2.3 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Pol_alpha_B_N PF08418.10 KFQ93009.1 - 0.43 10.5 37.3 0.36 10.8 9.4 3.4 3 0 0 3 3 3 0 DNA polymerase alpha subunit B N-terminal Mitofilin PF09731.9 KFQ93009.1 - 2.6 6.8 38.7 4.7 5.9 38.7 1.4 1 0 0 1 1 1 0 Mitochondrial inner membrane protein BBL5 PF07289.11 KFQ93009.1 - 6.1 5.8 8.5 11 4.9 8.5 1.3 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein WD40 PF00400.32 KFQ93010.1 - 1.1e-62 206.4 19.9 5e-10 39.8 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ93010.1 - 4.2e-27 94.3 2.0 4.1e-05 23.8 0.1 6.2 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFQ93010.1 - 8.7e-15 54.3 4.7 0.0017 17.1 0.1 4.8 1 1 4 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.11 KFQ93010.1 - 2.6e-12 47.0 0.1 3.1e-06 27.2 0.0 3.7 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFQ93010.1 - 1.5e-06 27.5 5.1 0.026 13.5 0.8 4.1 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFQ93010.1 - 1.5e-06 27.8 0.1 0.0091 15.3 0.0 3.3 1 1 3 4 4 4 3 WD40-like domain PALB2_WD40 PF16756.5 KFQ93010.1 - 6.5e-06 25.3 1.9 2.1 7.2 0.0 4.2 1 1 2 4 4 4 3 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 KFQ93010.1 - 0.00034 19.1 0.0 0.021 13.1 0.0 2.4 1 1 2 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz VID27 PF08553.10 KFQ93010.1 - 0.0077 15.3 0.0 0.11 11.5 0.0 2.6 2 1 1 4 4 4 2 VID27 C-terminal WD40-like domain Hira PF07569.11 KFQ93010.1 - 0.018 14.7 1.9 28 4.4 0.0 4.4 3 1 1 4 4 4 0 TUP1-like enhancer of split CDtoxinA PF03498.14 KFQ93010.1 - 0.039 13.5 1.2 0.26 10.9 0.1 2.5 1 1 0 2 2 2 0 Cytolethal distending toxin A/C domain SBD PF17882.1 KFQ93010.1 - 0.11 12.3 0.1 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 OAA-family lectin sugar binding domain Nucleoporin_N PF08801.11 KFQ93010.1 - 0.14 10.8 5.3 0.32 9.7 1.7 3.0 1 1 1 2 2 2 0 Nup133 N terminal like Hormone_recep PF00104.30 KFQ93011.1 - 4.1e-40 137.6 0.0 7e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Nuc_recep-AF1 PF11825.8 KFQ93011.1 - 5.1e-40 136.1 23.1 7.9e-40 135.5 23.1 1.3 1 0 0 1 1 1 1 Nuclear/hormone receptor activator site AF-1 zf-C4 PF00105.18 KFQ93011.1 - 4.1e-32 110.5 16.3 6.8e-32 109.8 16.3 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Collagen PF01391.18 KFQ93012.1 - 3.3e-164 532.8 681.3 1.1e-08 34.7 21.5 22.2 4 2 15 19 19 19 16 Collagen triple helix repeat (20 copies) COLFI PF01410.18 KFQ93012.1 - 2.4e-96 321.6 0.0 3.4e-96 321.1 0.0 1.2 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Laminin_G_2 PF02210.24 KFQ93012.1 - 7.4e-05 23.3 0.0 0.00012 22.6 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.6 KFQ93012.1 - 0.0022 18.2 0.0 0.0037 17.4 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_1 PF00054.23 KFQ93012.1 - 0.047 13.9 0.0 0.091 13.0 0.0 1.3 1 0 0 1 1 1 0 Laminin G domain OLF PF02191.16 KFQ93013.1 - 1.3e-89 300.1 7.5 2e-89 299.4 7.5 1.3 1 0 0 1 1 1 1 Olfactomedin-like domain Noelin-1 PF12308.8 KFQ93013.1 - 6.7e-49 164.0 8.9 2e-47 159.3 5.0 2.8 3 0 0 3 3 3 1 Neurogenesis glycoprotein Helo_like_N PF17111.5 KFQ93013.1 - 0.0013 18.1 0.7 0.0013 18.1 0.7 2.5 1 1 1 2 2 2 1 Fungal N-terminal domain of STAND proteins zf-C4H2 PF10146.9 KFQ93013.1 - 0.0036 17.6 0.9 0.0052 17.1 0.9 1.3 1 0 0 1 1 1 1 Zinc finger-containing protein Baculo_PEP_C PF04513.12 KFQ93013.1 - 0.011 15.8 2.0 0.087 12.9 1.1 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GCP_C_terminal PF04130.13 KFQ93013.1 - 0.013 15.0 2.3 0.022 14.2 2.3 1.3 1 0 0 1 1 1 0 Gamma tubulin complex component C-terminal Lipoprotein_7 PF01540.16 KFQ93013.1 - 0.02 14.2 2.7 0.03 13.6 2.7 1.2 1 0 0 1 1 1 0 Adhesin lipoprotein Atg14 PF10186.9 KFQ93013.1 - 0.059 12.5 8.4 0.11 11.5 8.4 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4795 PF16043.5 KFQ93013.1 - 0.065 12.8 11.5 0.44 10.1 11.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) NPV_P10 PF05531.12 KFQ93013.1 - 0.07 13.6 3.4 5.8 7.5 3.4 3.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Xpo1 PF08389.12 KFQ93013.1 - 0.084 12.9 1.8 0.1 12.6 0.4 1.7 1 1 0 1 1 1 0 Exportin 1-like protein APG17 PF04108.12 KFQ93013.1 - 0.1 11.7 10.2 0.2 10.7 10.2 1.4 1 1 0 1 1 1 0 Autophagy protein Apg17 Exonuc_VII_L PF02601.15 KFQ93013.1 - 0.11 12.1 5.9 0.18 11.4 5.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TBCC_N PF16752.5 KFQ93013.1 - 0.11 13.0 12.5 1.4 9.4 12.5 2.4 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain DUF1664 PF07889.12 KFQ93013.1 - 0.19 11.8 9.3 2.3 8.3 4.5 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.6 KFQ93013.1 - 0.23 11.8 10.6 8.4 6.8 9.5 2.6 1 1 0 1 1 1 0 Syntaxin-like protein FUSC PF04632.12 KFQ93013.1 - 0.41 9.1 3.7 0.58 8.6 3.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-Q PF13094.6 KFQ93013.1 - 0.47 10.6 13.2 1.3 9.3 13.2 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit MitMem_reg PF13012.6 KFQ93013.1 - 0.58 10.6 3.6 3.3 8.2 3.6 2.1 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function BLOC1_2 PF10046.9 KFQ93013.1 - 0.61 10.4 15.0 0.17 12.2 1.4 3.7 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Csm2_III-A PF03750.13 KFQ93013.1 - 0.81 10.5 8.6 4.8 8.1 4.2 2.4 1 1 1 2 2 2 0 Csm2 Type III-A CLZ PF16526.5 KFQ93013.1 - 0.92 9.9 14.8 2.5 8.5 4.4 3.4 2 2 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PriC PF07445.12 KFQ93013.1 - 0.98 9.3 13.7 0.54 10.2 7.3 2.2 2 0 0 2 2 2 0 Primosomal replication protein priC Bacillus_HBL PF05791.11 KFQ93013.1 - 1 9.2 6.9 8.6 6.2 2.9 2.3 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) ABC_tran_CTD PF16326.5 KFQ93013.1 - 1.4 9.2 15.5 0.56 10.5 2.7 3.7 1 1 3 4 4 4 0 ABC transporter C-terminal domain H-kinase_dim PF02895.14 KFQ93013.1 - 1.5 9.3 7.4 42 4.6 7.4 2.8 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain Laminin_II PF06009.12 KFQ93013.1 - 1.6 8.8 9.1 0.71 9.9 3.7 2.4 1 1 1 2 2 2 0 Laminin Domain II DUF2203 PF09969.9 KFQ93013.1 - 3.7 8.3 10.9 3.4 8.4 0.9 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Fib_alpha PF08702.10 KFQ93013.1 - 4.2 7.5 11.4 5.7 7.1 7.4 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Occludin_ELL PF07303.13 KFQ93013.1 - 5.3 7.8 13.5 24 5.7 0.6 2.7 1 1 1 2 2 2 0 Occludin homology domain DASH_Dad3 PF08656.10 KFQ93013.1 - 6.1 7.0 10.8 7 6.8 0.4 3.8 2 1 1 4 4 3 0 DASH complex subunit Dad3 FapA PF03961.13 KFQ93013.1 - 6.3 5.3 11.1 1.8 7.1 6.1 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A PCRF PF03462.18 KFQ93013.1 - 6.9 6.5 13.1 2 8.2 5.3 2.2 1 1 1 2 2 2 0 PCRF domain Spectrin PF00435.21 KFQ93013.1 - 8.4 6.9 12.6 17 6.0 0.6 2.5 1 1 1 2 2 2 0 Spectrin repeat TMPIT PF07851.13 KFQ93013.1 - 9.4 5.4 11.2 2.7 7.1 6.0 2.0 1 1 1 2 2 2 0 TMPIT-like protein PPP1R26_N PF15740.5 KFQ93014.1 - 0 1065.3 56.6 0 1064.6 56.6 1.3 1 0 0 1 1 1 1 Protein phosphatase 1 regulatory subunit 26 N-terminus WHEP-TRS PF00458.20 KFQ93014.1 - 0.59 10.3 8.7 3.5 7.8 1.2 3.3 4 0 0 4 4 4 0 WHEP-TRS domain Ribosomal_S2 PF00318.20 KFQ93015.1 - 3.4e-43 147.4 0.5 3.2e-22 78.8 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 PIP49_C PF12260.8 KFQ93016.1 - 1.9e-61 207.0 0.3 1.9e-61 207.0 0.3 1.7 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 PIP49_N PF14875.6 KFQ93016.1 - 1.1e-59 200.8 0.0 2.1e-59 199.9 0.0 1.4 1 0 0 1 1 1 1 N-term cysteine-rich ER, FAM69 EF-hand_1 PF00036.32 KFQ93016.1 - 0.001 18.5 0.1 0.0078 15.7 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 KFQ93016.1 - 0.007 15.8 0.2 0.06 12.9 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KFQ93016.1 - 0.16 12.5 0.0 0.41 11.1 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair Dockerin_1 PF00404.18 KFQ93016.1 - 0.18 12.1 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 Dockerin type I domain Acyltransferase PF01553.21 KFQ93017.1 - 1.2e-23 83.3 0.0 1.5e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase EMI PF07546.13 KFQ93018.1 - 3.5e-18 66.1 7.2 3.5e-18 66.1 7.2 2.5 2 1 0 2 2 1 1 EMI domain EGF_CA PF07645.15 KFQ93018.1 - 1.4e-10 41.2 6.6 1.4e-10 41.2 6.6 3.3 2 1 1 3 3 3 1 Calcium-binding EGF domain FXa_inhibition PF14670.6 KFQ93018.1 - 1.5e-09 37.9 8.5 1.5e-09 37.9 8.5 3.3 3 1 0 3 3 3 1 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFQ93018.1 - 2.9e-08 33.5 4.0 2.7e-06 27.2 0.8 3.5 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF_3 PF12947.7 KFQ93018.1 - 0.0002 21.5 3.7 0.0002 21.5 3.7 3.4 3 0 0 3 3 3 1 EGF domain EGF_2 PF07974.13 KFQ93018.1 - 0.0029 18.0 10.7 0.0029 18.0 10.7 3.6 4 0 0 4 4 4 1 EGF-like domain EGF PF00008.27 KFQ93018.1 - 0.0075 16.5 30.5 0.012 15.9 8.1 3.9 4 0 0 4 4 4 2 EGF-like domain hEGF PF12661.7 KFQ93018.1 - 0.011 16.3 8.6 0.011 16.3 8.6 4.1 4 0 0 4 4 4 0 Human growth factor-like EGF DUF5320 PF17253.2 KFQ93018.1 - 0.015 16.3 0.4 2 9.5 0.1 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5320) Seryl_tRNA_N PF02403.22 KFQ93018.1 - 0.026 14.8 0.1 0.095 12.9 0.0 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain bZIP_2 PF07716.15 KFQ93018.1 - 0.097 12.8 4.5 3.8 7.7 1.5 2.2 2 0 0 2 2 2 0 Basic region leucine zipper SlyX PF04102.12 KFQ93018.1 - 0.1 13.2 0.2 7.9 7.2 0.1 2.3 2 0 0 2 2 2 0 SlyX DUF4988 PF16378.5 KFQ93018.1 - 0.23 11.1 0.1 3.6 7.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function RANK_CRD_2 PF18278.1 KFQ93018.1 - 0.34 11.1 13.1 3.3 7.9 0.3 2.8 2 0 0 2 2 2 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Uds1 PF15456.6 KFQ93018.1 - 0.42 10.8 2.2 2.2 8.5 0.3 2.1 2 0 0 2 2 2 0 Up-regulated During Septation HSBP1 PF06825.12 KFQ93018.1 - 0.76 9.7 2.5 12 5.9 0.3 2.2 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Pox_A_type_inc PF04508.12 KFQ93018.1 - 4 7.5 9.0 0.61 10.0 1.2 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat EGF PF00008.27 KFQ93019.1 - 1.9e-107 350.9 242.7 1.5e-09 38.0 8.9 15.3 15 0 0 15 15 15 15 EGF-like domain hEGF PF12661.7 KFQ93019.1 - 2.8e-65 214.9 208.9 8.4e-07 29.4 8.8 17.5 17 0 0 17 17 17 15 Human growth factor-like EGF EGF_CA PF07645.15 KFQ93019.1 - 3.3e-49 164.8 235.8 8.8e-08 32.2 10.3 15.2 9 4 6 15 15 15 15 Calcium-binding EGF domain EGF_2 PF07974.13 KFQ93019.1 - 1.2e-19 70.3 257.6 0.0026 18.1 9.4 15.3 15 0 0 15 15 15 13 EGF-like domain EGF_3 PF12947.7 KFQ93019.1 - 1.2e-10 41.4 213.4 0.0017 18.5 2.9 16.4 9 6 6 15 15 15 10 EGF domain FXa_inhibition PF14670.6 KFQ93019.1 - 2.6e-07 30.8 210.1 0.4 11.0 4.0 15.7 4 2 11 15 15 15 8 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFQ93019.1 - 0.00024 20.9 204.5 0.007 16.3 5.2 19.1 17 7 0 17 17 17 9 Complement Clr-like EGF-like Ank_2 PF12796.7 KFQ93020.1 - 8e-38 128.9 23.4 1.5e-12 47.9 1.8 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 KFQ93020.1 - 1.3e-30 104.4 8.3 1.7e-05 25.0 0.0 6.8 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KFQ93020.1 - 6e-25 87.0 10.0 1.6e-10 41.0 0.2 5.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ93020.1 - 1.5e-23 80.3 1.6 0.00035 20.8 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 KFQ93020.1 - 4.6e-22 78.1 9.0 5.7e-07 30.0 0.0 5.1 2 1 4 6 6 6 5 Ankyrin repeats (many copies) PUB_1 PF18486.1 KFQ93020.1 - 0.069 13.0 0.5 3.3 7.6 0.1 2.6 2 0 0 2 2 2 0 PNGase/UBA- or UBX-containing domain Exo_endo_phos PF03372.23 KFQ93021.1 - 5.2e-09 36.0 0.0 8.9e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M16_C PF05193.21 KFQ93022.1 - 3.3e-42 144.6 0.0 6e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KFQ93022.1 - 2.5e-40 137.9 0.0 5.9e-40 136.7 0.0 1.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF2695 PF10905.8 KFQ93022.1 - 0.019 15.2 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) Tropomyosin PF00261.20 KFQ93023.1 - 0.0088 15.4 16.9 0.017 14.5 16.9 1.6 1 0 0 1 1 1 1 Tropomyosin ERM PF00769.19 KFQ93023.1 - 0.015 15.1 15.9 0.018 14.9 15.9 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family LNP1 PF15419.6 KFQ93023.1 - 0.024 14.9 5.3 0.034 14.4 5.3 1.3 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 Monooxygenase_B PF04744.12 KFQ93023.1 - 0.035 12.9 0.8 0.039 12.8 0.8 1.1 1 0 0 1 1 1 0 Monooxygenase subunit B protein AP1AR PF15745.5 KFQ93023.1 - 0.086 12.5 9.1 0.097 12.3 9.1 1.1 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein CENP-O PF09496.10 KFQ93023.1 - 0.28 11.2 5.6 0.31 11.0 5.6 1.2 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component HMMR_C PF15908.5 KFQ93023.1 - 0.56 10.5 16.2 1.9 8.7 5.3 2.3 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal PNMA PF14893.6 KFQ93023.1 - 0.57 9.5 10.7 0.82 9.0 10.7 1.3 1 0 0 1 1 1 0 PNMA V_ATPase_I PF01496.19 KFQ93023.1 - 0.65 7.8 10.8 0.71 7.7 10.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EPL1 PF10513.9 KFQ93023.1 - 1.4 9.3 7.6 1.8 9.0 7.6 1.3 1 1 0 1 1 1 0 Enhancer of polycomb-like DUF2514 PF10721.9 KFQ93023.1 - 1.5 8.9 10.3 1.2 9.2 7.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2514) TPR_MLP1_2 PF07926.12 KFQ93023.1 - 1.8 8.7 26.1 1.5 8.9 23.6 1.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF724 PF05266.14 KFQ93023.1 - 1.8 8.4 17.6 0.47 10.3 14.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) GAS PF13851.6 KFQ93023.1 - 1.9 7.8 25.4 0.16 11.3 9.0 1.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CLZ PF16526.5 KFQ93023.1 - 2.7 8.4 15.3 0.6 10.5 8.6 3.0 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Jnk-SapK_ap_N PF09744.9 KFQ93023.1 - 3.4 7.9 21.7 7.9 6.7 19.6 1.9 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 HAUS-augmin3 PF14932.6 KFQ93023.1 - 3.8 7.0 22.1 3.4 7.2 18.6 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF5094 PF17015.5 KFQ93023.1 - 4.2 7.5 16.5 29 4.7 16.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5094) Myb_DNA-binding PF00249.31 KFQ93024.1 - 2.6e-57 190.8 18.9 1.4e-15 57.2 1.2 5.8 5 0 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFQ93024.1 - 2e-42 143.2 26.0 2.5e-13 50.1 0.1 5.8 1 1 4 5 5 5 5 Myb-like DNA-binding domain SLIDE PF09111.10 KFQ93024.1 - 1.2e-11 44.6 11.2 0.0088 16.1 0.0 5.7 3 1 3 6 6 6 4 SLIDE SANT_DAMP1_like PF16282.5 KFQ93024.1 - 0.0026 17.9 10.0 0.65 10.2 0.6 4.5 2 2 2 4 4 4 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 KFQ93024.1 - 0.0099 16.0 0.1 1.5 9.1 0.0 3.0 2 0 0 2 2 2 1 Rap1 Myb domain Rap1_C PF11626.8 KFQ93024.1 - 0.029 14.5 0.0 0.5 10.5 0.0 2.8 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF281 PF03436.13 KFQ93024.1 - 0.24 11.8 0.8 0.85 10.1 0.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF281) DUF5320 PF17253.2 KFQ93024.1 - 0.48 11.5 1.6 3.6 8.7 1.6 2.6 1 0 0 1 1 1 0 Family of unknown function (DUF5320) CARD PF00619.21 KFQ93025.1 - 1.8e-21 75.9 0.9 1.4e-20 73.1 0.0 2.8 2 0 0 2 2 2 1 Caspase recruitment domain CARD_2 PF16739.5 KFQ93025.1 - 6.4e-05 22.9 0.4 0.00028 20.8 0.0 2.4 2 0 0 2 2 2 1 Caspase recruitment domain PspB PF06667.12 KFQ93025.1 - 0.5 10.5 0.0 0.5 10.5 0.0 3.5 4 0 0 4 4 4 0 Phage shock protein B zf-DNL PF05180.12 KFQ93026.1 - 1.5e-26 92.1 0.1 1.8e-26 91.8 0.1 1.1 1 0 0 1 1 1 1 DNL zinc finger Ribosomal_S27e PF01667.17 KFQ93026.1 - 0.046 13.4 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S27 GoLoco PF02188.17 KFQ93027.1 - 2.1e-41 138.9 27.3 2.3e-11 42.9 0.7 4.5 4 0 0 4 4 4 4 GoLoco motif TPR_12 PF13424.6 KFQ93027.1 - 6.4e-40 135.3 27.7 1.6e-09 37.9 0.9 5.9 4 2 2 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ93027.1 - 8.2e-36 120.4 28.8 2.1e-05 24.1 0.0 8.8 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ93027.1 - 7e-30 100.9 20.0 5.5e-06 26.0 0.3 8.8 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ93027.1 - 1.8e-21 74.5 25.1 0.0054 16.9 0.1 8.9 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ93027.1 - 6.3e-20 69.6 30.0 0.002 18.1 0.1 9.0 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ93027.1 - 1.4e-19 69.3 18.4 0.00053 19.8 0.0 8.4 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_MalT PF17874.1 KFQ93027.1 - 6.3e-07 29.1 8.2 0.03 13.7 3.4 3.1 2 1 1 3 3 3 3 MalT-like TPR region TPR_14 PF13428.6 KFQ93027.1 - 6.7e-07 29.6 4.2 29 5.8 0.0 7.5 4 2 3 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFQ93027.1 - 2.6e-06 27.5 0.5 17 6.4 0.0 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ93027.1 - 6.8e-05 23.4 10.7 0.095 13.4 0.1 6.7 3 2 1 6 6 6 1 Tetratricopeptide repeat Rapsyn_N PF10579.9 KFQ93027.1 - 8.7e-05 22.5 1.6 3 8.0 0.1 4.6 3 3 2 5 5 5 2 Rapsyn N-terminal myristoylation and linker region TPR_11 PF13414.6 KFQ93027.1 - 0.00067 19.3 23.5 0.16 11.7 0.2 7.8 7 3 0 7 7 6 1 TPR repeat UreE_C PF05194.12 KFQ93027.1 - 0.085 13.4 1.0 5.5 7.5 0.1 2.9 2 1 1 3 3 2 0 UreE urease accessory protein, C-terminal domain ANAPC5 PF12862.7 KFQ93027.1 - 0.16 12.1 1.0 26 5.0 0.0 3.8 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 FliJ PF02050.16 KFQ93027.1 - 0.2 11.9 3.8 0.74 10.0 0.2 3.2 2 2 1 3 3 3 0 Flagellar FliJ protein TPR_17 PF13431.6 KFQ93027.1 - 0.46 11.0 16.0 21 5.8 0.0 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFQ93027.1 - 1.5 9.6 8.2 1.8e+02 3.1 0.1 6.3 7 1 0 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ93027.1 - 4.3 7.6 15.1 19 5.5 0.0 4.8 3 2 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 CENP-K PF11802.8 KFQ93028.1 - 3.4 7.2 14.8 4.9 6.7 7.4 2.0 1 1 1 2 2 2 0 Centromere-associated protein K OmpH PF03938.14 KFQ93028.1 - 7.3 6.9 15.8 1.2 9.5 11.5 1.7 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) QSOX_Trx1 PF18108.1 KFQ93030.1 - 4.5e-46 155.5 0.0 9.1e-46 154.5 0.0 1.5 1 0 0 1 1 1 1 QSOX Trx-like domain FAD_SOX PF18371.1 KFQ93030.1 - 3e-43 146.4 0.0 2.9e-42 143.2 0.0 2.7 3 0 0 3 3 3 1 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Evr1_Alr PF04777.13 KFQ93030.1 - 6.9e-27 93.9 0.3 2.7e-26 92.0 0.4 2.0 2 0 0 2 2 2 1 Erv1 / Alr family Thioredoxin PF00085.20 KFQ93030.1 - 0.014 15.4 0.1 0.11 12.5 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin Peptidase_A22B PF04258.13 KFQ93030.1 - 0.22 11.0 2.3 0.16 11.5 0.6 1.6 2 0 0 2 2 2 0 Signal peptide peptidase Zn-ribbon_8 PF09723.10 KFQ93030.1 - 0.22 11.7 2.6 7.6 6.7 0.2 2.7 2 0 0 2 2 2 0 Zinc ribbon domain Homeodomain PF00046.29 KFQ93031.1 - 1.8e-21 75.7 2.1 2.8e-21 75.1 2.1 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ93031.1 - 9.3e-05 22.3 0.2 0.00026 20.8 0.0 1.9 2 1 0 2 2 2 1 Homeobox KN domain DUF4449 PF14613.6 KFQ93031.1 - 0.065 13.3 0.1 0.094 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) BTB PF00651.31 KFQ93032.1 - 1.3e-23 83.4 0.0 2.3e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BEN PF10523.9 KFQ93032.1 - 4.7e-10 39.5 0.1 1.2e-09 38.3 0.1 1.7 1 0 0 1 1 1 1 BEN domain UBA PF00627.31 KFQ93033.1 - 4.1e-17 61.7 1.0 1.4e-07 31.2 0.0 2.4 2 0 0 2 2 2 2 UBA/TS-N domain STI1 PF17830.1 KFQ93033.1 - 0.0041 17.0 0.3 0.014 15.3 0.3 2.0 1 0 0 1 1 1 1 STI1 domain UBA_3 PF09288.10 KFQ93033.1 - 0.0077 16.0 0.1 1.3 8.9 0.0 3.0 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain UBA_2 PF08587.11 KFQ93033.1 - 0.019 15.1 0.0 0.058 13.5 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) CAMSAP_CH PF11971.8 KFQ93034.1 - 7.4e-35 118.7 0.3 1.8e-34 117.4 0.3 1.7 1 0 0 1 1 1 1 CAMSAP CH domain CAMSAP_CC1 PF17095.5 KFQ93034.1 - 7.7e-24 83.3 5.4 7.7e-24 83.3 5.4 3.0 2 1 1 3 3 3 1 Spectrin-binding region of Ca2+-Calmodulin CAMSAP_CKK PF08683.11 KFQ93034.1 - 2.7e-13 50.1 0.1 5.2e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated CH PF00307.31 KFQ93034.1 - 0.051 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Calponin homology (CH) domain Galactosyl_T PF01762.21 KFQ93035.1 - 4.3e-38 131.1 0.0 5.4e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 KFQ93035.1 - 1.7e-06 27.7 0.0 3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Proteasom_PSMB PF10508.9 KFQ93036.1 - 3.8e-187 622.7 0.0 4.5e-187 622.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit RICTOR_V PF14668.6 KFQ93036.1 - 1e-05 25.7 0.1 0.76 10.1 0.0 4.2 3 1 2 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_2 PF13646.6 KFQ93036.1 - 1.9e-05 25.0 0.1 0.035 14.5 0.0 4.5 4 1 1 5 5 5 1 HEAT repeats Cnd1 PF12717.7 KFQ93036.1 - 0.0015 18.6 0.1 4.2 7.4 0.1 3.3 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 STAG PF08514.11 KFQ93036.1 - 0.012 15.5 0.0 0.09 12.7 0.1 2.3 2 0 0 2 2 2 0 STAG domain V-ATPase_H_C PF11698.8 KFQ93036.1 - 0.018 15.1 0.1 3.8 7.7 0.0 3.3 3 0 0 3 3 3 0 V-ATPase subunit H CutA1 PF03091.15 KFQ93037.1 - 9.7e-33 112.0 0.0 1.2e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein Mtf2_C PF14061.6 KFQ93038.1 - 3.2e-27 94.4 0.1 5.3e-27 93.7 0.1 1.4 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 Chromo PF00385.24 KFQ93038.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 KFQ93039.1 - 4.5e-15 55.3 17.3 7.5e-10 38.5 1.6 2.5 2 0 0 2 2 2 2 PHD-finger Tudor_2 PF18104.1 KFQ93039.1 - 3.2e-14 52.3 0.2 7.2e-14 51.2 0.2 1.6 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain PHD_2 PF13831.6 KFQ93039.1 - 0.00015 21.2 2.8 0.00015 21.2 2.8 3.5 3 2 0 3 3 3 1 PHD-finger Prok-RING_1 PF14446.6 KFQ93039.1 - 0.0017 18.3 1.5 0.0017 18.3 1.5 3.3 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 DUF4537 PF15057.6 KFQ93039.1 - 0.0023 18.0 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) C1_1 PF00130.22 KFQ93039.1 - 0.014 15.3 0.6 0.014 15.3 0.6 3.9 3 1 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) LBR_tudor PF09465.10 KFQ93039.1 - 0.14 12.0 0.3 0.25 11.2 0.3 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain TRAF_BIRC3_bd PF16673.5 KFQ93040.1 - 3.7e-21 74.7 2.5 7.8e-21 73.6 2.5 1.5 1 0 0 1 1 1 1 TNF receptor-associated factor BIRC3 binding domain zf-TRAF PF02176.18 KFQ93040.1 - 1e-06 29.3 18.3 1.6e-06 28.7 5.3 3.2 3 1 0 3 3 3 2 TRAF-type zinc finger zf-C3HC4 PF00097.25 KFQ93040.1 - 0.00061 19.6 10.8 0.00061 19.6 10.8 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 KFQ93040.1 - 0.002 18.5 6.9 0.002 18.5 6.9 4.2 4 0 0 4 4 4 1 TRAF-like zinc-finger zf-C3HC4_3 PF13920.6 KFQ93040.1 - 0.0081 16.0 8.2 0.0081 16.0 8.2 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFQ93040.1 - 0.0089 16.0 3.1 0.0089 16.0 3.1 3.2 3 1 0 3 3 3 1 RING-type zinc-finger Sina PF03145.16 KFQ93040.1 - 0.069 13.1 11.3 0.24 11.3 7.2 2.3 1 1 1 2 2 2 0 Seven in absentia protein family DUF641 PF04859.12 KFQ93040.1 - 0.084 13.2 0.6 2.5 8.5 0.6 2.3 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) zf_UBZ PF18439.1 KFQ93040.1 - 0.8 9.3 6.4 8.2 6.1 0.2 3.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-ACC PF17848.1 KFQ93040.1 - 2.6 8.2 0.0 2.6 8.2 0.0 4.5 5 0 0 5 5 5 0 Acetyl-coA carboxylase zinc finger domain zf-C3HC4_2 PF13923.6 KFQ93040.1 - 7.1 6.6 18.6 0.07 13.0 7.5 3.1 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) LRR_9 PF14580.6 KFQ93041.1 - 1e-19 70.7 11.8 2.3e-19 69.6 5.3 4.5 3 1 1 4 4 4 2 Leucine-rich repeat LRR_4 PF12799.7 KFQ93041.1 - 6e-14 51.9 26.6 3.1e-08 33.8 3.5 5.4 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFQ93041.1 - 6.9e-12 45.0 16.0 2.2e-07 30.5 1.4 4.2 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 KFQ93041.1 - 3.5e-05 23.5 8.8 0.76 10.0 0.1 5.0 4 0 0 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.33 KFQ93041.1 - 0.019 15.5 8.8 12 6.9 0.0 5.0 4 0 0 4 4 4 0 Leucine Rich Repeat Ras PF00071.22 KFQ93042.1 - 8.6e-61 204.3 0.1 9.9e-61 204.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ93042.1 - 2.5e-32 111.6 0.0 3.8e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ93042.1 - 1.7e-12 47.2 0.0 2.1e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFQ93042.1 - 2.8e-05 23.7 0.0 0.0013 18.3 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFQ93042.1 - 4.9e-05 23.4 0.0 9.3e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFQ93042.1 - 0.00031 20.7 0.1 0.64 9.9 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KFQ93042.1 - 0.0014 18.1 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 KFQ93042.1 - 0.0027 17.5 0.0 0.065 13.0 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 KFQ93042.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF1863 PF08937.11 KFQ93042.1 - 0.055 13.8 0.0 0.096 13.0 0.0 1.5 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) Septin PF00735.18 KFQ93042.1 - 0.082 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Septin AAA PF00004.29 KFQ93042.1 - 0.11 12.9 0.0 0.47 10.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFQ93042.1 - 0.14 12.4 0.1 0.47 10.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain Gelsolin PF00626.22 KFQ93043.1 - 3.3e-107 350.5 0.2 1.9e-20 72.5 0.0 6.2 6 0 0 6 6 6 6 Gelsolin repeat Lipoprotein_Ltp PF07553.11 KFQ93043.1 - 0.0099 16.1 0.2 2.1 8.6 0.1 2.5 2 0 0 2 2 2 2 Host cell surface-exposed lipoprotein CutA1 PF03091.15 KFQ93043.1 - 0.074 12.9 1.5 8.6 6.3 0.0 3.3 4 0 0 4 4 4 0 CutA1 divalent ion tolerance protein Band_7 PF01145.25 KFQ93044.1 - 2.9e-35 121.9 0.7 3.5e-35 121.6 0.7 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KFQ93044.1 - 0.00035 20.3 0.2 0.00053 19.8 0.2 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family GP68 PF17469.2 KFQ93044.1 - 0.14 12.6 0.1 0.34 11.3 0.1 1.6 1 0 0 1 1 1 0 Phage protein Gp68 TTL PF03133.15 KFQ93045.1 - 9.7e-67 225.2 0.0 1.5e-66 224.5 0.0 1.3 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 KFQ93045.1 - 1.8e-08 34.0 0.0 0.0001 21.6 0.0 2.6 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 KFQ93045.1 - 5.1e-06 25.9 0.0 0.0084 15.4 0.0 2.8 2 1 1 3 3 3 2 YheC/D like ATP-grasp RimK PF08443.11 KFQ93045.1 - 0.0093 15.6 0.0 2.9 7.5 0.0 2.3 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 KFQ93045.1 - 0.024 14.7 0.0 0.49 10.4 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain PID PF00640.23 KFQ93046.1 - 4.2e-31 107.9 2.0 4.2e-31 107.9 2.0 1.8 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) DUF2285 PF10074.9 KFQ93046.1 - 0.035 14.7 4.2 6.3 7.5 2.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2285) DivIC PF04977.15 KFQ93046.1 - 0.2 11.5 4.1 0.45 10.3 4.1 1.6 1 0 0 1 1 1 0 Septum formation initiator CHCH PF06747.13 KFQ93049.1 - 1.3e-08 34.7 1.4 1.7e-08 34.4 1.4 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KFQ93049.1 - 0.036 14.1 1.9 0.11 12.5 2.0 1.7 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KFQ93049.1 - 0.053 13.6 0.6 0.069 13.2 0.6 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.17 KFQ93049.1 - 0.058 13.6 1.8 0.077 13.2 1.8 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb MORN PF02493.20 KFQ93050.1 - 1.5e-10 40.3 1.4 0.00014 21.5 0.1 4.1 4 0 0 4 4 4 3 MORN repeat Y_Y_Y PF07495.13 KFQ93050.1 - 0.097 12.6 0.2 0.35 10.9 0.1 1.9 1 1 1 2 2 2 0 Y_Y_Y domain RRM_1 PF00076.22 KFQ93051.1 - 5.2e-12 45.4 0.1 8.2e-12 44.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 KFQ93051.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated RRF PF01765.19 KFQ93052.1 - 1.5e-43 148.5 5.8 2.3e-43 147.9 5.8 1.3 1 0 0 1 1 1 1 Ribosome recycling factor YvbH_ext PF11724.8 KFQ93052.1 - 0.037 14.3 0.7 0.074 13.4 0.7 1.5 1 0 0 1 1 1 0 YvbH-like oligomerisation region YtxH PF12732.7 KFQ93052.1 - 0.093 13.3 9.7 0.28 11.7 6.7 2.7 2 1 0 2 2 2 0 YtxH-like protein DUF3810 PF12725.7 KFQ93052.1 - 1.1 8.6 5.1 0.37 10.1 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) An_peroxidase PF03098.15 KFQ93053.1 - 1.4e-46 159.2 0.0 7.4e-39 133.7 0.0 2.7 1 1 1 2 2 2 2 Animal haem peroxidase EGF PF00008.27 KFQ93053.1 - 0.00025 21.3 13.1 0.0006 20.1 13.1 1.7 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 KFQ93053.1 - 0.057 14.1 5.8 0.13 12.9 5.8 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF Phosducin PF02114.16 KFQ93054.1 - 2.9e-32 111.7 3.3 3.1e-32 111.6 3.3 1.0 1 0 0 1 1 1 1 Phosducin ROQ_II PF18386.1 KFQ93055.1 - 1.2e-33 114.7 1.5 4.2e-33 112.9 0.6 2.2 2 0 0 2 2 2 1 Roquin II domain zf-CCCH PF00642.24 KFQ93055.1 - 2e-06 27.6 1.9 2e-06 27.6 1.9 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_UBOX PF13445.6 KFQ93055.1 - 1.1e-05 25.3 7.5 1.1e-05 25.3 7.5 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFQ93055.1 - 1.2e-05 25.5 7.4 1.2e-05 25.5 7.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KFQ93055.1 - 1.6e-05 24.8 7.8 3.7e-05 23.6 7.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFQ93055.1 - 9e-05 22.3 4.5 9e-05 22.3 4.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFQ93055.1 - 0.00023 20.9 11.5 0.0049 16.7 8.0 3.3 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFQ93055.1 - 0.002 18.2 6.6 0.002 18.2 6.6 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf_CCCH_4 PF18345.1 KFQ93055.1 - 0.002 18.1 1.4 0.0049 16.9 1.4 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KFQ93055.1 - 0.0025 17.6 1.0 0.0047 16.7 1.0 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-C3HC4 PF00097.25 KFQ93055.1 - 0.0027 17.5 8.4 0.007 16.2 8.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Xin PF08043.12 KFQ93055.1 - 0.0053 16.3 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Xin repeat zf-C3HC4_2 PF13923.6 KFQ93055.1 - 0.0086 15.9 7.8 0.026 14.4 7.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KFQ93055.1 - 0.8 9.9 8.0 0.29 11.3 5.0 1.8 2 0 0 2 2 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KFQ93055.1 - 1.3 8.8 5.6 2.8 7.8 5.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 KFQ93055.1 - 1.8 8.5 5.0 4.2 7.3 5.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) BTB PF00651.31 KFQ93056.1 - 6.2e-20 71.5 2.0 6.2e-20 71.5 2.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFQ93056.1 - 2.6e-14 52.9 22.8 5e-08 33.0 0.1 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ93056.1 - 4.6e-14 52.0 34.4 2.2e-05 24.7 1.2 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ93056.1 - 6.2e-11 42.2 32.6 0.001 19.7 0.6 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 KFQ93056.1 - 3.9e-07 30.2 18.2 0.0027 18.1 0.6 3.9 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFQ93056.1 - 0.018 14.8 18.4 0.024 14.4 0.5 4.7 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KFQ93056.1 - 0.083 13.2 21.4 0.38 11.1 8.5 4.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KFQ93056.1 - 0.12 12.7 23.4 1.4 9.3 4.7 5.0 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 KFQ93056.1 - 0.17 11.8 0.1 0.17 11.8 0.1 3.3 3 0 0 3 3 2 0 LYAR-type C2HC zinc finger Sprouty PF05210.13 KFQ93056.1 - 0.21 12.0 7.1 0.065 13.6 3.3 2.1 2 0 0 2 2 2 0 Sprouty protein (Spry) zf-C2H2_8 PF15909.5 KFQ93056.1 - 0.29 11.5 17.6 0.63 10.4 3.5 3.8 1 1 3 4 4 4 0 C2H2-type zinc ribbon zf-UBP PF02148.19 KFQ93056.1 - 0.35 11.2 10.1 3.4 8.0 10.1 2.4 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C2H2_3rep PF18868.1 KFQ93056.1 - 0.36 11.5 10.1 2.5 8.8 2.6 3.2 2 2 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 KFQ93056.1 - 0.39 10.5 27.2 0.63 9.9 0.3 4.7 4 0 0 4 4 4 0 C2H2-type zinc-finger domain ROS_MUCR PF05443.11 KFQ93056.1 - 0.88 9.6 4.6 1.5 8.9 0.3 2.6 1 1 0 2 2 2 0 ROS/MUCR transcriptional regulator protein zf-MYST PF17772.1 KFQ93056.1 - 5.1 6.8 9.7 6.8 6.4 0.4 3.6 3 0 0 3 3 3 0 MYST family zinc finger domain zf-C2HE PF16278.5 KFQ93056.1 - 8 7.0 23.9 11 6.6 5.1 3.9 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger BTB PF00651.31 KFQ93057.1 - 1.8e-18 66.8 0.1 5.8e-18 65.1 0.1 1.9 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 KFQ93057.1 - 5.2e-18 64.4 38.8 1.2e-05 25.5 2.6 5.2 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ93057.1 - 9.3e-17 60.6 18.8 3.7e-07 30.3 0.7 5.7 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ93057.1 - 1.7e-12 47.1 36.9 0.00017 22.2 2.7 5.1 5 0 0 5 5 4 4 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFQ93057.1 - 0.00019 21.1 21.4 0.0029 17.3 2.4 4.3 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-met PF12874.7 KFQ93057.1 - 0.00026 21.3 22.6 0.015 15.6 1.8 4.6 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFQ93057.1 - 0.00036 20.2 23.9 0.0053 16.5 2.3 4.3 4 0 0 4 4 4 3 zinc-finger C2H2-type DUF899 PF05988.12 KFQ93057.1 - 0.00099 18.7 0.1 0.00099 18.7 0.1 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF899) zf-C2H2_2 PF12756.7 KFQ93057.1 - 0.0038 17.5 24.9 0.33 11.3 0.8 5.3 1 1 4 5 5 5 4 C2H2 type zinc-finger (2 copies) zf-CHCC PF10276.9 KFQ93057.1 - 0.12 12.4 4.2 0.15 12.1 0.1 2.7 3 0 0 3 3 2 0 Zinc-finger domain zf-C2H2_jaz PF12171.8 KFQ93057.1 - 0.14 12.5 19.2 2.3 8.6 0.1 4.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.15 KFQ93057.1 - 0.4 10.6 3.4 9.1 6.3 0.0 3.3 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain GAGA PF09237.11 KFQ93057.1 - 0.42 10.4 8.3 27 4.7 0.1 4.2 1 1 3 4 4 4 0 GAGA factor AHH PF14412.6 KFQ93057.1 - 0.43 10.7 7.0 67 3.6 7.0 2.8 1 1 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH zf-C2H2_6 PF13912.6 KFQ93057.1 - 1.6 8.8 29.4 1.2 9.2 2.5 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-Dof PF02701.15 KFQ93057.1 - 2.2 8.5 8.0 0.094 12.9 0.8 2.4 1 1 1 2 2 2 0 Dof domain, zinc finger Zn-ribbon_8 PF09723.10 KFQ93057.1 - 3.9 7.7 9.0 29 4.9 2.3 3.8 2 1 0 3 3 3 0 Zinc ribbon domain FYVE PF01363.21 KFQ93057.1 - 4.7 7.4 22.1 33 4.7 15.0 3.5 1 1 1 2 2 2 0 FYVE zinc finger RabGAP-TBC PF00566.18 KFQ93058.1 - 2.7e-57 193.9 1.6 2.7e-57 193.9 1.6 2.6 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DUF3694 PF12473.8 KFQ93058.1 - 3e-32 112.4 0.1 3e-32 112.4 0.1 2.8 3 1 0 3 3 3 1 Kinesin protein PID PF00640.23 KFQ93058.1 - 5.5e-06 26.5 3.5 2.4e-05 24.4 0.0 3.1 3 1 0 3 3 3 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFQ93058.1 - 0.0014 18.8 0.2 0.0053 16.9 0.0 2.1 2 0 0 2 2 2 1 Phosphotyrosine-binding domain UPF0242 PF06785.11 KFQ93058.1 - 0.0072 16.4 9.0 0.0072 16.4 9.0 3.3 1 1 2 3 3 3 2 Uncharacterised protein family (UPF0242) N-terminus ERM PF00769.19 KFQ93058.1 - 0.11 12.3 54.7 0.02 14.7 48.6 2.4 2 1 1 3 3 3 0 Ezrin/radixin/moesin family DUF3452 PF11934.8 KFQ93058.1 - 1.3 8.5 12.5 1.2 8.7 0.7 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3452) Lebercilin PF15619.6 KFQ93058.1 - 3.6 7.2 45.9 4.9 6.8 36.3 2.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DZF PF07528.14 KFQ93059.1 - 4.2e-79 265.7 0.0 6.6e-79 265.0 0.0 1.3 1 0 0 1 1 1 1 DZF domain dsrm PF00035.26 KFQ93059.1 - 4.2e-26 91.5 0.0 1.8e-13 51.0 0.0 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif SGP PF17228.2 KFQ93059.1 - 0.0015 19.3 2.1 0.0015 19.3 2.1 1.9 2 0 0 2 2 2 1 Sulphur globule protein DND1_DSRM PF14709.7 KFQ93059.1 - 0.2 11.9 8.3 4.1 7.7 0.1 3.8 4 2 0 4 4 4 0 double strand RNA binding domain from DEAD END PROTEIN 1 JIP_LZII PF16471.5 KFQ93059.1 - 0.33 11.2 2.2 0.38 11.0 0.3 2.0 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II EGF PF00008.27 KFQ93061.1 - 4.4e-94 308.2 200.3 1.5e-10 41.2 9.5 16.1 15 2 1 16 16 16 15 EGF-like domain hEGF PF12661.7 KFQ93061.1 - 3e-63 208.5 167.7 2e-07 31.4 3.8 17.6 16 0 0 16 16 16 15 Human growth factor-like EGF EGF_CA PF07645.15 KFQ93061.1 - 5.7e-26 90.4 213.6 3.3e-05 24.0 7.1 15.3 9 3 6 15 15 15 13 Calcium-binding EGF domain EGF_2 PF07974.13 KFQ93061.1 - 1.2e-14 54.4 218.6 0.0022 18.3 10.2 15.3 13 2 1 14 14 14 10 EGF-like domain EGF_3 PF12947.7 KFQ93061.1 - 7.5e-10 38.8 190.0 0.035 14.3 8.8 15.8 12 5 2 14 14 14 11 EGF domain FXa_inhibition PF14670.6 KFQ93061.1 - 2.9e-06 27.4 183.1 0.0072 16.6 6.6 15.4 6 5 8 14 14 14 8 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFQ93061.1 - 2.2e-05 24.3 10.1 0.0011 18.9 2.0 16.1 14 3 0 14 14 14 8 Complement Clr-like EGF-like nos_propeller_2 PF18793.1 KFQ93061.1 - 0.12 12.7 0.0 53 4.2 0.0 3.5 3 0 0 3 3 3 0 Nitrous oxide reductase propeller repeat 2 DENN PF02141.21 KFQ93062.1 - 4e-47 160.6 2.7 4e-47 160.6 2.7 1.9 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 KFQ93062.1 - 7.3e-11 42.7 0.7 7.3e-11 42.7 0.7 2.5 3 0 0 3 3 3 1 uDENN domain dDENN PF03455.19 KFQ93062.1 - 2.6e-10 40.1 2.3 6.2e-10 38.9 2.3 1.7 1 0 0 1 1 1 1 dDENN domain SCIMP PF15050.6 KFQ93062.1 - 0.53 10.7 2.7 0.86 10.1 0.3 2.5 2 0 0 2 2 2 0 SCIMP protein Pkinase PF00069.25 KFQ93063.1 - 1.7e-64 217.8 0.0 2.1e-64 217.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ93063.1 - 2.1e-46 158.3 0.0 2.5e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFQ93063.1 - 2.4e-05 23.5 0.2 5e-05 22.4 0.2 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KFQ93063.1 - 0.0011 17.9 0.0 0.0014 17.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFQ93063.1 - 0.002 17.5 0.0 0.003 16.9 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFQ93063.1 - 0.0027 17.1 0.0 0.0047 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RecG_N PF17190.4 KFQ93063.1 - 0.045 14.5 0.3 0.25 12.1 0.2 2.2 3 0 0 3 3 3 0 RecG N-terminal helical domain PIP49_C PF12260.8 KFQ93063.1 - 0.077 12.6 0.2 4.1 7.0 0.1 2.2 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 Gln_deamidase_2 PF18626.1 KFQ93063.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Glutaminase Proteasome PF00227.26 KFQ93064.1 - 7.8e-45 152.7 0.1 1e-44 152.3 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KFQ93064.1 - 1.6e-13 49.8 0.4 1.6e-13 49.8 0.4 1.8 2 0 0 2 2 2 1 Proteasome beta subunits C terminal 7tm_2 PF00002.24 KFQ93065.1 - 7.7e-45 153.1 24.6 1.3e-44 152.3 24.6 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Pentaxin PF00354.17 KFQ93065.1 - 8e-26 90.9 0.1 1.6e-25 89.9 0.1 1.5 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.6 KFQ93065.1 - 2.4e-13 50.5 0.1 4.4e-13 49.6 0.1 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily GPS PF01825.21 KFQ93065.1 - 9.8e-10 38.8 3.3 9.8e-10 38.8 3.3 2.9 3 0 0 3 3 3 1 GPCR proteolysis site, GPS, motif Dicty_CAR PF05462.11 KFQ93065.1 - 1.2e-05 24.6 7.6 2.2e-05 23.8 7.6 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor GAIN PF16489.5 KFQ93065.1 - 1.4e-05 24.7 0.5 3.1e-05 23.5 0.3 1.7 1 1 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Tex_N PF09371.10 KFQ93065.1 - 0.00023 20.9 0.0 0.00054 19.7 0.0 1.5 1 0 0 1 1 1 1 Tex-like protein N-terminal domain Laminin_G_2 PF02210.24 KFQ93065.1 - 0.016 15.8 0.0 0.056 14.0 0.0 2.0 1 0 0 1 1 1 0 Laminin G domain Lectin_C PF00059.21 KFQ93065.1 - 0.027 15.2 0.4 0.67 10.7 0.0 2.9 2 0 0 2 2 2 0 Lectin C-type domain zf-C4 PF00105.18 KFQ93066.1 - 4e-28 97.7 17.9 8.2e-28 96.7 17.9 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFQ93066.1 - 2.4e-26 92.6 6.2 4.8e-26 91.6 6.2 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Ribosomal_L29 PF00831.23 KFQ93067.1 - 0.00054 19.9 0.7 0.00054 19.9 0.7 2.6 2 1 1 3 3 3 1 Ribosomal L29 protein XFP_N PF09364.10 KFQ93067.1 - 0.042 12.7 0.0 0.043 12.6 0.0 1.0 1 0 0 1 1 1 0 XFP N-terminal domain SCAI PF12070.8 KFQ93068.1 - 6e-206 685.4 6.4 1.6e-205 684.1 6.4 1.6 1 1 0 1 1 1 1 Protein SCAI GRIP PF01465.20 KFQ93069.1 - 5.9e-15 54.9 0.5 2.5e-14 52.9 0.5 2.2 1 0 0 1 1 1 1 GRIP domain DUF3450 PF11932.8 KFQ93069.1 - 0.0042 16.4 13.9 0.0042 16.4 13.9 8.1 2 1 6 8 8 8 2 Protein of unknown function (DUF3450) Nuc_N PF14448.6 KFQ93069.1 - 4.5 7.2 5.6 31 4.5 0.2 3.3 3 0 0 3 3 3 0 Nuclease N terminal DUF5631 PF18645.1 KFQ93069.1 - 5.2 7.5 6.4 12 6.4 0.3 4.2 3 1 1 4 4 4 0 Family of unknown function (DUF5631) P16-Arc PF04699.14 KFQ93070.1 - 6.2e-32 111.1 0.1 6.6e-32 111.0 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 KFQ93070.1 - 0.032 14.6 0.0 0.048 14.0 0.0 1.3 1 0 0 1 1 1 0 Dip2/Utp12 Family Metallophos PF00149.28 KFQ93071.1 - 8.1e-30 104.8 0.1 1.1e-29 104.4 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Kelch_3 PF13415.6 KFQ93072.1 - 1.5e-25 88.9 7.9 7.4e-08 32.5 0.1 4.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 KFQ93072.1 - 9.2e-25 86.0 0.0 1.3e-07 31.1 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 KFQ93072.1 - 5.3e-23 80.5 2.8 2.7e-07 30.6 0.0 3.6 2 1 2 4 4 4 3 Kelch motif Kelch_5 PF13854.6 KFQ93072.1 - 1e-20 73.2 5.4 3.1e-06 27.1 0.1 5.0 4 1 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 KFQ93072.1 - 2.7e-20 72.1 10.9 1.1e-06 28.5 0.1 4.2 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KFQ93072.1 - 3.3e-15 55.4 1.8 2.4e-05 24.1 0.0 4.5 4 1 0 4 4 4 3 Kelch motif PQQ_3 PF13570.6 KFQ93072.1 - 1.1 9.9 5.7 1.5 9.4 0.2 3.2 2 1 1 3 3 3 0 PQQ-like domain HSP70 PF00012.20 KFQ93073.1 - 1.2e-262 872.5 10.3 1.4e-262 872.3 10.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFQ93073.1 - 3.5e-17 62.2 0.1 8e-17 61.0 0.1 1.6 1 1 0 1 1 1 1 MreB/Mbl protein Hydantoinase_A PF01968.18 KFQ93073.1 - 0.0036 16.6 0.2 0.013 14.8 0.1 1.9 1 1 0 1 1 1 1 Hydantoinase/oxoprolinase DDR PF08841.10 KFQ93073.1 - 0.0085 15.1 1.1 0.024 13.7 0.6 1.8 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 KFQ93073.1 - 0.036 13.8 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Radial_spoke_3 PF06098.11 KFQ93073.1 - 1.4 8.1 13.2 0.043 13.1 6.4 1.8 2 0 0 2 2 2 0 Radial spoke protein 3 RasGAP PF00616.19 KFQ93074.1 - 3.9e-35 121.5 0.1 1.2e-34 119.9 0.1 1.9 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase VPS9 PF02204.18 KFQ93074.1 - 8.6e-29 99.8 0.1 3.1e-28 98.0 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KFQ93074.1 - 3.1e-12 46.6 0.2 1.1e-11 44.8 0.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) EF-hand_14 PF17959.1 KFQ93074.1 - 0.12 12.7 0.1 0.89 9.9 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain SURF2 PF05477.11 KFQ93074.1 - 0.28 10.8 5.8 2.5 7.7 0.1 2.4 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) CRIM PF16978.5 KFQ93075.1 - 2.7e-36 124.8 0.0 5.7e-36 123.7 0.0 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1 PF05422.12 KFQ93075.1 - 7.1e-33 114.2 12.0 6.2e-30 104.6 7.4 3.6 2 1 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) SIN1_PH PF16979.5 KFQ93075.1 - 3.7e-28 98.0 0.3 6.8e-28 97.1 0.3 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology E3_UbLigase_RBR PF18091.1 KFQ93075.1 - 0.17 12.1 0.6 0.77 9.9 0.0 2.3 2 0 0 2 2 2 0 E3 Ubiquitin Ligase RBR C-terminal domain PBC PF03792.13 KFQ93076.1 - 1.4e-67 227.1 0.0 3e-67 226.1 0.0 1.5 2 0 0 2 2 2 1 PBC domain Homeodomain PF00046.29 KFQ93076.1 - 2.3e-19 69.0 1.2 4.6e-19 68.0 1.2 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ93076.1 - 2e-15 56.4 0.0 4.5e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 KFQ93076.1 - 0.016 15.0 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Sec15 PF04091.12 KFQ93076.1 - 0.026 13.9 0.4 0.039 13.3 0.4 1.2 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like LZ3wCH PF18517.1 KFQ93076.1 - 0.04 14.0 0.2 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 Leucine zipper with capping helix domain Auxin_canalis PF05703.11 KFQ93076.1 - 0.31 10.9 8.6 1.4 8.8 8.6 1.9 1 1 0 1 1 1 0 Auxin canalisation DUF2464 PF10240.9 KFQ93077.1 - 6.9e-85 284.7 0.0 7.9e-85 284.5 0.0 1.0 1 0 0 1 1 1 1 Multivesicular body subunit 12 Homeodomain PF00046.29 KFQ93078.1 - 2.5e-18 65.7 2.5 5.9e-18 64.5 2.5 1.7 1 0 0 1 1 1 1 Homeodomain LIM PF00412.22 KFQ93078.1 - 9.3e-17 61.0 11.5 1.5e-16 60.3 11.5 1.4 1 0 0 1 1 1 1 LIM domain Homeobox_KN PF05920.11 KFQ93078.1 - 8.2e-05 22.4 0.0 0.00019 21.2 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Pentapeptide_4 PF13599.6 KFQ93079.1 - 0.028 14.6 0.9 0.26 11.5 0.0 2.0 1 1 1 2 2 2 0 Pentapeptide repeats (9 copies) BH4 PF02180.17 KFQ93079.1 - 5.3 7.0 10.6 78 3.2 0.1 4.4 2 2 3 5 5 5 0 Bcl-2 homology region 4 BTB PF00651.31 KFQ93080.1 - 9.3e-27 93.5 0.0 1.6e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFQ93080.1 - 3.5e-09 36.7 16.1 1.7e-06 28.1 0.5 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ93080.1 - 6.9e-07 29.4 23.9 0.0015 18.8 2.5 4.4 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ93080.1 - 0.00012 22.6 21.4 0.031 15.1 1.8 4.3 3 0 0 3 3 3 3 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 KFQ93080.1 - 0.0032 17.4 2.9 0.0032 17.4 2.9 2.1 2 0 0 2 2 2 1 SprT-like zinc ribbon domain zf-met PF12874.7 KFQ93080.1 - 0.14 12.6 10.8 11 6.5 0.7 4.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFQ93080.1 - 0.2 12.0 7.5 0.79 10.1 4.8 2.8 3 0 0 3 3 3 0 C2H2-type zinc ribbon DUF2256 PF10013.9 KFQ93080.1 - 2.3 8.4 7.6 1.6 8.9 0.7 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn-ribbon_8 PF09723.10 KFQ93080.1 - 3.2 8.0 6.5 8.7 6.6 0.3 3.2 2 1 1 3 3 3 0 Zinc ribbon domain zf-C2H2_6 PF13912.6 KFQ93080.1 - 4 7.6 18.4 0.71 9.9 0.1 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger Zn_Tnp_IS91 PF14319.6 KFQ93080.1 - 4 7.5 7.9 0.47 10.5 1.6 2.6 1 1 1 2 2 2 0 Transposase zinc-binding domain BTB PF00651.31 KFQ93081.1 - 6e-26 90.8 0.2 9.7e-26 90.2 0.2 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 KFQ93081.1 - 6.9e-17 60.9 16.9 3.7e-05 24.0 2.1 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ93081.1 - 2.1e-14 53.2 16.9 2e-07 31.1 0.6 4.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ93081.1 - 7.1e-13 48.2 14.8 0.00036 21.1 0.3 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFQ93081.1 - 1.2e-08 35.1 7.2 0.0042 17.4 0.2 3.9 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFQ93081.1 - 6.8e-06 26.2 6.3 0.26 11.6 0.0 3.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding DUF3342 PF11822.8 KFQ93081.1 - 1.2e-05 25.4 0.1 2.6e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) zf-C2H2_11 PF16622.5 KFQ93081.1 - 1.7e-05 24.4 14.2 0.0052 16.5 0.2 4.1 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-BED PF02892.15 KFQ93081.1 - 0.00047 20.1 15.4 0.31 11.1 0.7 3.7 1 1 2 3 3 3 2 BED zinc finger DUF4187 PF13821.6 KFQ93081.1 - 0.0054 16.5 0.5 1.6 8.6 0.1 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) zf-C2H2_6 PF13912.6 KFQ93081.1 - 0.019 14.9 11.4 0.71 9.9 0.8 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFQ93081.1 - 0.024 15.0 10.8 0.14 12.5 0.1 3.9 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 KFQ93081.1 - 0.034 13.9 5.6 1.2 9.0 0.1 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Chordopox_A33R PF05966.12 KFQ93081.1 - 0.045 13.0 0.1 0.086 12.1 0.1 1.4 1 0 0 1 1 1 0 Chordopoxvirus A33R protein PyrI_C PF02748.15 KFQ93081.1 - 0.44 10.5 7.3 7.4 6.6 0.1 3.5 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-Di19 PF05605.12 KFQ93081.1 - 0.7 10.2 9.0 0.4 11.0 2.8 2.9 2 1 1 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding HNH_5 PF14279.6 KFQ93081.1 - 2.2 8.2 7.3 5.5 6.9 0.1 3.3 3 0 0 3 3 3 0 HNH endonuclease zf-C2HC_2 PF13913.6 KFQ93081.1 - 3.2 7.7 12.0 3.3 7.7 0.1 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KFQ93081.1 - 3.3 7.4 5.6 4 7.1 0.3 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 KFQ93081.1 - 3.9 8.2 8.7 19 6.0 0.6 3.4 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2HE PF16278.5 KFQ93081.1 - 5.7 7.5 9.5 8.1 7.0 0.1 3.4 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-AN1 PF01428.16 KFQ93081.1 - 9.2 6.5 10.4 5.1 7.3 0.2 3.7 3 0 0 3 3 3 0 AN1-like Zinc finger RasGEF PF00617.19 KFQ93082.1 - 2.1e-51 174.7 3.4 1.6e-50 171.8 0.9 2.1 1 1 1 2 2 2 2 RasGEF domain PH PF00169.29 KFQ93082.1 - 1.5e-10 41.5 0.0 3.2e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 PH domain Fibrinogen_C PF00147.18 KFQ93083.1 - 2.6e-74 249.8 12.1 3.6e-74 249.3 12.1 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fer4_NifH PF00142.18 KFQ93083.1 - 0.015 14.8 1.1 0.044 13.2 1.4 1.6 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF16 PF01519.16 KFQ93083.1 - 0.55 10.8 10.8 0.43 11.1 3.0 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 LMBR1 PF04791.16 KFQ93083.1 - 2.4 7.0 4.0 3.7 6.3 4.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein WD40 PF00400.32 KFQ93084.1 - 4.7e-16 58.9 11.3 1.4e-05 25.7 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat F-box-like PF12937.7 KFQ93084.1 - 5.1e-08 32.7 4.7 1.7e-07 31.0 3.2 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFQ93084.1 - 1.9e-05 24.4 1.3 7.5e-05 22.5 0.6 2.3 1 1 1 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 KFQ93084.1 - 0.002 18.4 1.1 5.1 7.5 0.0 4.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Sugar_tr PF00083.24 KFQ93085.1 - 5.2e-98 328.8 25.4 6.1e-98 328.6 25.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFQ93085.1 - 3.9e-31 108.3 29.7 3.9e-31 108.3 29.7 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFQ93085.1 - 1.4e-05 23.8 3.9 1.4e-05 23.8 3.9 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_2_1 PF04971.12 KFQ93085.1 - 5 7.2 10.4 3.7 7.6 0.2 3.6 4 0 0 4 4 4 0 Bacteriophage P21 holin S Rap_GAP PF02145.15 KFQ93086.1 - 4.5e-68 228.5 0.1 9.2e-68 227.5 0.1 1.6 1 0 0 1 1 1 1 Rap/ran-GAP CNH PF00780.22 KFQ93086.1 - 6.8e-68 229.2 0.3 1.4e-67 228.3 0.2 1.5 2 0 0 2 2 2 1 CNH domain HEPN_STY4199 PF18729.1 KFQ93086.1 - 0.044 13.0 0.3 2.3 7.3 0.1 2.2 2 0 0 2 2 2 0 STY4199-like HEPN Vg_Tdu PF07545.14 KFQ93087.1 - 3.5e-20 71.5 0.4 5.2e-20 70.9 0.4 1.3 1 0 0 1 1 1 1 Vestigial/Tondu family HNOB PF07700.15 KFQ93087.1 - 0.12 12.4 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Haem-NO-binding Ig_3 PF13927.6 KFQ93088.1 - 4.5e-29 100.9 0.3 3.7e-13 49.9 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFQ93088.1 - 1.4e-23 82.7 0.0 1.2e-10 41.4 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KFQ93088.1 - 1.6e-21 76.4 0.1 3.9e-09 36.7 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFQ93088.1 - 4.3e-21 74.9 0.1 9.8e-08 32.1 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.12 KFQ93088.1 - 1.5e-16 60.2 3.7 4.6e-15 55.4 0.0 2.7 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFQ93088.1 - 9.1e-14 51.6 0.3 0.0034 17.5 0.0 4.2 3 1 1 4 4 4 3 Immunoglobulin V-set domain C1-set PF07654.15 KFQ93088.1 - 4.1e-10 39.9 0.1 4.3e-09 36.6 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Ig_5 PF16681.5 KFQ93088.1 - 5.9e-07 29.8 0.0 0.027 14.8 0.0 3.2 3 0 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFQ93088.1 - 8.1e-06 26.0 0.0 0.051 13.8 0.0 3.5 3 1 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFQ93088.1 - 0.00027 20.9 0.0 1.8 8.7 0.0 3.2 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain BPD_transp_1 PF00528.22 KFQ93088.1 - 0.11 12.2 1.5 0.16 11.7 1.5 1.1 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component DUF4462 PF14692.6 KFQ93090.1 - 0.1 12.1 0.2 0.17 11.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) CBM_48 PF02922.18 KFQ93092.1 - 1e-16 61.1 0.1 2.3e-16 59.9 0.1 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase_C PF02806.18 KFQ93092.1 - 2.7e-16 59.8 0.0 6.9e-16 58.5 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 KFQ93092.1 - 1.5e-14 54.4 2.3 4.4e-12 46.2 0.2 2.6 2 1 1 3 3 3 2 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KFQ93092.1 - 0.023 13.8 0.6 0.047 12.8 0.1 1.7 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain AMPK1_CBM PF16561.5 KFQ93092.1 - 0.13 12.5 0.1 0.33 11.2 0.1 1.6 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase Ig_3 PF13927.6 KFQ93093.1 - 2.9e-10 40.6 0.3 7.9e-09 36.0 0.3 2.1 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ93093.1 - 1.2e-08 34.9 0.0 0.00087 19.3 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFQ93093.1 - 0.00015 22.0 0.0 0.0014 19.0 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFQ93093.1 - 0.00051 20.1 0.0 1.1 9.5 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFQ93093.1 - 0.0054 16.7 0.0 0.17 11.9 0.0 2.1 1 1 0 1 1 1 1 C17orf99 Ig domain V-set PF07686.17 KFQ93093.1 - 0.007 16.5 0.0 2.4 8.4 0.0 2.1 1 1 1 2 2 2 2 Immunoglobulin V-set domain Ig_6 PF18452.1 KFQ93093.1 - 0.071 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFQ93094.1 - 3.3e-72 238.6 0.0 1.9e-22 79.1 0.0 4.7 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ93094.1 - 3.8e-62 206.9 3.3 5.8e-17 62.1 0.1 5.8 6 0 0 6 6 5 4 Immunoglobulin domain ig PF00047.25 KFQ93094.1 - 8.2e-38 128.5 0.0 1.4e-08 34.7 0.0 4.7 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFQ93094.1 - 5.8e-35 119.5 0.0 1.1e-08 35.3 0.0 5.1 5 0 0 5 5 5 4 Immunoglobulin domain fn3 PF00041.21 KFQ93094.1 - 4.5e-33 113.4 9.8 2.3e-12 47.1 0.3 4.2 3 0 0 3 3 3 3 Fibronectin type III domain V-set PF07686.17 KFQ93094.1 - 9.1e-22 77.3 7.7 3.4e-09 36.8 0.0 7.8 6 2 1 7 7 7 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFQ93094.1 - 6.3e-10 39.0 3.6 0.15 12.2 0.0 5.8 6 0 0 6 6 6 3 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFQ93094.1 - 2.2e-09 36.7 0.0 1 9.0 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin domain Ig_5 PF16681.5 KFQ93094.1 - 5.4e-09 36.3 0.0 0.34 11.3 0.0 4.7 4 0 0 4 4 4 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Pur_ac_phosph_N PF16656.5 KFQ93094.1 - 0.0002 21.8 3.4 0.13 12.9 0.2 3.9 3 1 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Ig_C17orf99 PF17736.1 KFQ93094.1 - 0.00097 19.1 0.1 7.8 6.6 0.0 4.5 4 1 1 5 5 5 1 C17orf99 Ig domain Big_4 PF07532.11 KFQ93094.1 - 0.038 13.7 2.6 0.22 11.3 0.6 2.9 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 4) Izumo-Ig PF16706.5 KFQ93094.1 - 0.077 13.1 0.2 36 4.5 0.0 4.0 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 KFQ93094.1 - 0.11 12.7 0.0 36 4.6 0.0 3.8 4 0 0 4 4 4 0 Natural killer cell receptor 2B4 fn3_4 PF16794.5 KFQ93094.1 - 0.12 12.3 0.0 17 5.4 0.0 2.8 2 0 0 2 2 2 0 Fibronectin-III type domain TFIIE-A_C PF11521.8 KFQ93094.1 - 0.29 11.5 2.1 9.4 6.6 0.9 2.6 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha I-set PF07679.16 KFQ93096.1 - 7.3e-65 215.1 0.0 5.6e-23 80.8 0.0 5.1 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ93096.1 - 1.9e-53 178.9 2.3 6.3e-16 58.8 0.1 5.7 5 0 0 5 5 5 4 Immunoglobulin domain fn3 PF00041.21 KFQ93096.1 - 3.1e-37 126.8 11.5 7.5e-15 55.1 0.9 4.2 3 0 0 3 3 3 3 Fibronectin type III domain ig PF00047.25 KFQ93096.1 - 5.9e-37 125.7 0.1 1.1e-09 38.3 0.0 4.8 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFQ93096.1 - 6.5e-36 122.5 0.2 2.6e-11 43.7 0.0 4.6 4 0 0 4 4 4 4 Immunoglobulin domain V-set PF07686.17 KFQ93096.1 - 2.6e-25 88.7 8.2 2e-08 34.4 0.0 6.5 6 2 0 6 6 5 4 Immunoglobulin V-set domain Ig_6 PF18452.1 KFQ93096.1 - 4.3e-13 48.6 0.0 0.00045 19.7 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin domain Ig_5 PF16681.5 KFQ93096.1 - 1.7e-05 25.1 0.0 0.17 12.3 0.0 3.8 4 0 0 4 4 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 KFQ93096.1 - 5.9e-05 23.0 0.0 2.7 8.1 0.0 4.2 4 0 0 4 4 4 2 C17orf99 Ig domain Ig_4 PF16680.5 KFQ93096.1 - 8.6e-05 22.7 0.1 1 9.7 0.0 4.5 4 1 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Receptor_2B4 PF11465.8 KFQ93096.1 - 0.0045 17.2 0.2 8.9 6.6 0.0 4.3 3 2 1 4 4 4 1 Natural killer cell receptor 2B4 Izumo-Ig PF16706.5 KFQ93096.1 - 0.022 14.8 0.5 59 3.8 0.0 4.3 5 0 0 5 5 5 0 Izumo-like Immunoglobulin domain Adeno_E3_CR1 PF02440.15 KFQ93096.1 - 0.052 13.3 0.3 0.46 10.3 0.0 2.8 4 0 0 4 4 3 0 Adenovirus E3 region protein CR1 fn3_4 PF16794.5 KFQ93096.1 - 0.071 13.0 0.1 8.9 6.3 0.0 3.2 3 0 0 3 3 3 0 Fibronectin-III type domain PRP38_assoc PF12871.7 KFQ93096.1 - 8.4 7.1 7.6 6.6 7.4 4.4 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Ig_3 PF13927.6 KFQ93097.1 - 2.5e-18 66.4 0.0 3.5e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ93097.1 - 3.9e-16 58.9 0.0 5.6e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFQ93097.1 - 1.1e-12 48.1 0.0 1.5e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFQ93097.1 - 2.4e-08 34.0 0.0 5.5e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFQ93097.1 - 6.6e-05 23.0 0.0 0.0023 18.1 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFQ93097.1 - 0.00024 21.1 0.0 0.00027 20.9 0.0 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.12 KFQ93097.1 - 0.05 13.7 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family Ig_6 PF18452.1 KFQ93097.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain Lipase PF00151.19 KFQ93100.1 - 4.9e-82 275.9 0.0 6.5e-82 275.5 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 KFQ93100.1 - 0.014 16.0 0.0 0.018 15.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFQ93100.1 - 0.095 12.3 0.0 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold ABC_membrane PF00664.23 KFQ93102.1 - 9.4e-59 199.3 31.2 3e-30 105.8 10.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFQ93102.1 - 2.4e-55 186.8 0.6 4.4e-31 108.2 0.1 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFQ93102.1 - 3e-09 36.6 7.7 0.00028 20.4 0.2 4.2 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KFQ93102.1 - 1.8e-07 31.2 0.5 0.0056 16.8 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KFQ93102.1 - 6.6e-06 26.6 0.1 0.082 13.3 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KFQ93102.1 - 7.4e-06 25.6 0.9 0.12 12.2 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFQ93102.1 - 1.1e-05 25.4 1.0 0.15 12.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KFQ93102.1 - 5.1e-05 23.4 1.9 0.0046 17.0 0.4 2.8 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.17 KFQ93102.1 - 0.00014 22.0 1.9 0.065 13.3 0.1 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_23 PF13476.6 KFQ93102.1 - 0.0004 20.9 3.4 0.036 14.6 0.2 2.8 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 KFQ93102.1 - 0.00048 20.4 0.3 0.61 10.4 0.2 3.0 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KFQ93102.1 - 0.00078 18.8 0.5 0.38 10.0 0.1 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_21 PF13304.6 KFQ93102.1 - 0.00091 19.1 6.3 1.9 8.2 0.1 4.1 3 2 1 5 5 5 1 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 KFQ93102.1 - 0.0017 17.5 0.1 1.3 8.0 0.1 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.6 KFQ93102.1 - 0.0071 15.9 0.3 0.23 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KFQ93102.1 - 0.0098 15.1 6.0 1.2 8.2 0.0 3.1 2 1 0 2 2 2 1 NB-ARC domain AAA_30 PF13604.6 KFQ93102.1 - 0.017 14.9 0.3 6.1 6.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain ABC_ATPase PF09818.9 KFQ93102.1 - 0.023 13.5 0.2 7.3 5.3 0.0 3.4 4 0 0 4 4 4 0 Predicted ATPase of the ABC class AAA_7 PF12775.7 KFQ93102.1 - 0.026 14.0 0.3 9.1 5.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KFQ93102.1 - 0.031 13.6 0.3 7.1 5.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family MeaB PF03308.16 KFQ93102.1 - 0.035 13.1 0.3 0.39 9.7 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 KFQ93102.1 - 0.039 14.0 0.4 16 5.5 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IIGP PF05049.13 KFQ93102.1 - 0.041 12.9 0.9 2.3 7.2 0.1 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Sigma54_activat PF00158.26 KFQ93102.1 - 0.044 13.5 0.3 6.1 6.5 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain GTP_EFTU PF00009.27 KFQ93102.1 - 0.051 13.1 0.0 3.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain NACHT PF05729.12 KFQ93102.1 - 0.058 13.3 1.1 2.2 8.2 0.0 3.2 3 0 0 3 3 3 0 NACHT domain TrwB_AAD_bind PF10412.9 KFQ93102.1 - 0.061 12.2 0.1 3 6.6 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_15 PF13175.6 KFQ93102.1 - 0.087 12.5 0.2 4.5 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 KFQ93102.1 - 0.13 11.8 1.9 6.9 6.2 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KFQ93102.1 - 0.17 12.5 0.1 40 4.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 KFQ93102.1 - 0.31 10.8 1.3 11 5.7 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AIG1 PF04548.16 KFQ93102.1 - 0.88 8.9 3.5 22 4.3 0.1 3.0 3 0 0 3 3 3 0 AIG1 family HSP70 PF00012.20 KFQ93103.1 - 3.6e-113 378.8 0.3 6.1e-81 272.4 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KFQ93103.1 - 3e-14 52.6 0.2 6.5e-10 38.3 0.0 3.0 3 0 0 3 3 3 2 MreB/Mbl protein BcrAD_BadFG PF01869.20 KFQ93103.1 - 0.0035 16.9 0.0 2.6 7.5 0.0 3.0 2 1 1 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 KFQ93103.1 - 0.0094 16.4 0.2 0.77 10.2 0.0 3.3 2 2 0 2 2 2 1 Cell division protein FtsA StbA PF06406.11 KFQ93103.1 - 0.027 13.7 0.0 0.067 12.4 0.0 1.7 2 0 0 2 2 2 0 StbA protein DDR PF08841.10 KFQ93103.1 - 0.034 13.1 0.4 0.39 9.7 0.1 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Raco_middle PF17651.1 KFQ93103.1 - 0.1 12.3 0.4 9.7 5.9 0.0 2.9 3 0 0 3 3 3 0 RACo middle region SLY PF12485.8 KFQ93105.1 - 1.2e-52 178.8 10.6 1.2e-52 178.8 10.6 2.2 2 0 0 2 2 2 1 Lymphocyte signaling adaptor protein SAM_2 PF07647.17 KFQ93105.1 - 2e-08 34.2 0.2 4.6e-08 33.0 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFQ93105.1 - 6.7e-08 32.9 0.1 1.7e-07 31.6 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 KFQ93105.1 - 7.4e-05 22.4 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFQ93105.1 - 0.022 14.4 0.0 0.045 13.4 0.0 1.6 1 0 0 1 1 1 0 SH3 domain SAM_KSR1 PF13543.6 KFQ93105.1 - 0.19 11.9 1.6 0.5 10.5 0.1 2.2 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 NRIP1_repr_4 PF15690.5 KFQ93107.1 - 4.8e-167 555.0 8.7 4.8e-167 555.0 8.7 2.6 3 0 0 3 3 3 1 Nuclear receptor-interacting protein 1 repression 4 NRIP1_repr_1 PF15687.5 KFQ93107.1 - 2.2e-141 471.0 19.6 2.2e-141 471.0 19.6 2.8 2 0 0 2 2 2 1 Nuclear receptor-interacting protein 1 repression 1 NRIP1_repr_2 PF15688.5 KFQ93107.1 - 5.3e-128 427.5 23.0 5.3e-128 427.5 23.0 3.2 3 2 1 4 4 4 1 Nuclear receptor-interacting protein 1 repression 2 NRIP1_repr_3 PF15689.5 KFQ93107.1 - 2.3e-44 149.6 2.3 2.3e-44 149.6 2.3 3.4 2 0 0 2 2 2 1 Nuclear receptor-interacting protein 1 repression 3 Pentapeptide_4 PF13599.6 KFQ93108.1 - 0.0087 16.2 0.0 0.015 15.4 0.0 1.5 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Phenol_monoox PF04663.12 KFQ93108.1 - 0.75 10.0 12.6 32 4.8 3.1 3.0 1 1 1 2 2 2 0 Phenol hydroxylase conserved region UCH PF00443.29 KFQ93109.1 - 4.3e-48 164.1 0.1 7.5e-48 163.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UIM PF02809.20 KFQ93109.1 - 0.00047 19.9 1.6 0.00047 19.9 1.6 3.7 4 0 0 4 4 4 2 Ubiquitin interaction motif UCH_1 PF13423.6 KFQ93109.1 - 0.002 17.8 0.9 0.014 15.0 0.1 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 KFQ93109.1 - 0.0028 17.4 2.3 0.0041 16.9 0.2 2.3 3 0 0 3 3 3 1 UBA-like domain RNase_E_G PF10150.9 KFQ93109.1 - 0.051 13.0 0.3 0.24 10.8 0.2 2.1 2 0 0 2 2 2 0 Ribonuclease E/G family V-set PF07686.17 KFQ93110.1 - 3.8e-24 85.0 0.6 9.3e-19 67.6 0.0 3.2 2 1 1 3 3 3 2 Immunoglobulin V-set domain I-set PF07679.16 KFQ93110.1 - 1.9e-17 63.1 0.1 1.9e-08 34.3 0.1 2.5 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ93110.1 - 3.3e-16 59.6 0.3 6.7e-09 36.2 0.2 2.7 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFQ93110.1 - 1.8e-15 57.0 0.9 6.6e-10 39.2 0.1 3.2 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFQ93110.1 - 7e-15 55.0 0.0 5.9e-07 29.6 0.1 3.0 2 1 0 2 2 2 2 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFQ93110.1 - 0.00011 22.1 0.0 0.079 13.0 0.0 2.9 3 0 0 3 3 3 1 C17orf99 Ig domain Ig_4 PF16680.5 KFQ93110.1 - 0.00015 21.9 0.2 0.072 13.4 0.1 3.0 2 1 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFQ93110.1 - 0.00035 20.9 0.1 0.042 14.3 0.1 3.0 3 0 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set_CD47 PF08204.11 KFQ93110.1 - 0.0019 18.2 0.0 0.6 10.1 0.0 2.5 2 1 0 2 2 2 1 CD47 immunoglobulin-like domain Ig_6 PF18452.1 KFQ93110.1 - 0.002 17.6 0.0 0.18 11.4 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain FAM163 PF15069.6 KFQ93110.1 - 0.0043 17.5 0.0 0.0082 16.6 0.0 1.4 1 0 0 1 1 1 1 FAM163 family Izumo-Ig PF16706.5 KFQ93110.1 - 0.0094 16.0 0.0 0.81 9.8 0.0 2.5 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain Adeno_E3_CR2 PF02439.15 KFQ93110.1 - 0.028 14.2 0.4 0.059 13.1 0.4 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 KFQ93110.1 - 0.045 13.7 0.0 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 Syndecan domain C2-set PF05790.15 KFQ93110.1 - 0.05 13.8 0.7 2.1 8.6 0.0 2.8 3 0 0 3 3 3 0 Immunoglobulin C2-set domain Mucin15 PF15672.5 KFQ93110.1 - 0.059 12.8 3.3 0.043 13.3 1.4 1.6 1 1 0 1 1 1 0 Cell-membrane associated Mucin15 EphA2_TM PF14575.6 KFQ93110.1 - 0.069 14.0 0.0 0.13 13.2 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Tweety PF04906.13 KFQ93110.1 - 0.12 11.1 0.1 0.16 10.6 0.1 1.1 1 0 0 1 1 1 0 Tweety EURL PF06937.11 KFQ93111.1 - 2e-164 545.9 6.9 2.3e-164 545.7 6.9 1.0 1 0 0 1 1 1 1 EURL protein XRCC4 PF06632.12 KFQ93111.1 - 0.018 13.9 0.7 0.03 13.2 0.7 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Lectin_C PF00059.21 KFQ93112.1 - 1.4e-13 51.5 0.1 3e-13 50.4 0.1 1.5 1 0 0 1 1 1 1 Lectin C-type domain DUF3377 PF11857.8 KFQ93112.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Trypsin PF00089.26 KFQ93113.1 - 5.4e-41 140.8 0.2 5.9e-41 140.7 0.2 1.0 1 0 0 1 1 1 1 Trypsin I-set PF07679.16 KFQ93114.1 - 7.8e-84 275.9 0.8 1.5e-19 69.8 0.0 5.7 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ93114.1 - 1e-67 224.7 6.9 2.2e-16 60.2 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 KFQ93114.1 - 7.1e-48 160.7 0.9 2.6e-10 40.3 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin domain Ig_2 PF13895.6 KFQ93114.1 - 2.4e-46 155.9 0.7 2.2e-10 40.7 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin domain fn3 PF00041.21 KFQ93114.1 - 1.2e-29 102.4 2.0 1.8e-16 60.2 0.6 2.6 2 0 0 2 2 2 2 Fibronectin type III domain V-set PF07686.17 KFQ93114.1 - 1e-26 93.2 2.1 1.3e-05 25.3 0.0 8.1 4 3 1 5 5 5 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFQ93114.1 - 9.7e-13 48.0 1.0 0.00072 19.6 0.0 5.4 5 0 0 5 5 5 3 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFQ93114.1 - 5e-12 45.7 0.1 0.016 15.3 0.0 4.9 5 0 0 5 5 5 2 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 KFQ93114.1 - 1.3e-11 44.3 0.0 0.12 12.4 0.0 5.5 5 0 0 5 5 5 3 C17orf99 Ig domain Ig_5 PF16681.5 KFQ93114.1 - 3.8e-09 36.8 0.2 0.12 12.8 0.0 5.1 5 0 0 5 5 5 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFQ93114.1 - 3.9e-09 35.9 0.0 1.2 8.8 0.0 5.4 5 0 0 5 5 5 2 Immunoglobulin domain Ig_4 PF16680.5 KFQ93114.1 - 1.4e-08 34.9 0.8 1 9.7 0.0 5.9 5 1 0 5 5 5 2 T-cell surface glycoprotein CD3 delta chain Adeno_E3_CR1 PF02440.15 KFQ93114.1 - 1e-06 28.4 0.1 0.26 11.1 0.0 3.9 3 0 0 3 3 3 2 Adenovirus E3 region protein CR1 Receptor_2B4 PF11465.8 KFQ93114.1 - 1.8e-06 28.1 0.4 3.6 7.8 0.0 5.1 5 1 0 5 5 5 1 Natural killer cell receptor 2B4 Herpes_gE PF02480.16 KFQ93114.1 - 0.00039 19.3 0.1 0.31 9.7 0.1 3.4 1 1 1 3 3 3 1 Alphaherpesvirus glycoprotein E Pur_ac_phosph_N PF16656.5 KFQ93114.1 - 0.00042 20.8 1.7 0.0042 17.6 0.9 3.0 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFQ93114.1 - 0.011 16.1 0.0 2.5 8.4 0.0 2.9 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III C2-set PF05790.15 KFQ93114.1 - 0.039 14.1 0.5 3.8 7.7 0.0 4.2 5 0 0 5 5 4 0 Immunoglobulin C2-set domain DUF4462 PF14692.6 KFQ93115.1 - 0.11 12.0 0.3 0.18 11.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) CLPTM1 PF05602.12 KFQ93117.1 - 8.8e-145 483.0 2.2 1e-144 482.8 2.2 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 KFQ93117.1 - 0.014 15.1 2.5 0.48 10.2 0.2 2.7 2 0 0 2 2 2 0 PQ loop repeat DRY_EERY PF09750.9 KFQ93118.1 - 4e-14 53.0 4.3 4e-14 53.0 4.3 2.4 2 1 0 2 2 2 1 Alternative splicing regulator Trnau1ap PF17654.1 KFQ93118.1 - 8 7.4 10.4 8.8 7.3 8.2 2.2 2 1 0 2 2 2 0 Selenocysteine tRNA 1 associated proteins Qua1 PF16274.5 KFQ93119.1 - 2e-28 98.0 0.6 2e-28 98.0 0.6 2.1 2 0 0 2 2 2 1 Qua1 domain Sam68-YY PF16568.5 KFQ93119.1 - 5.3e-19 68.7 34.5 1.1e-18 67.7 34.5 1.6 1 0 0 1 1 1 1 Tyrosine-rich domain of Sam68 KH_1 PF00013.29 KFQ93119.1 - 5.5e-07 29.3 0.0 9.7e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 KH domain STAR_dimer PF16544.5 KFQ93119.1 - 0.083 12.5 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Homodimerisation region of STAR domain protein zf-H2C2_2 PF13465.6 KFQ93121.1 - 8e-43 143.0 133.6 1.6e-07 31.4 0.3 21.0 21 1 0 21 21 21 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ93121.1 - 1.7e-42 141.6 156.6 6.9e-05 23.1 3.3 19.4 19 0 0 19 19 19 17 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ93121.1 - 1.8e-35 118.5 149.9 0.0053 17.5 2.9 19.4 19 0 0 19 19 19 18 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFQ93121.1 - 6.1e-29 99.4 128.0 2.5e-09 36.7 1.1 15.5 17 1 0 17 17 17 9 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KFQ93121.1 - 9.7e-15 54.6 95.1 0.0014 18.9 0.7 12.3 11 1 1 12 12 12 8 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KFQ93121.1 - 9.3e-05 22.7 5.3 9.3e-05 22.7 5.3 15.1 4 2 12 16 16 16 3 C2H2 type zinc-finger (2 copies) Rad50_zn_hook PF04423.14 KFQ93121.1 - 0.0054 16.5 7.0 0.089 12.6 0.1 4.3 3 0 0 3 3 3 1 Rad50 zinc hook motif zf-C2H2_6 PF13912.6 KFQ93121.1 - 0.011 15.7 0.1 0.011 15.7 0.1 14.4 18 0 0 18 18 18 0 C2H2-type zinc finger zf-met PF12874.7 KFQ93121.1 - 0.029 14.8 0.4 0.029 14.8 0.4 14.8 16 0 0 16 16 15 0 Zinc-finger of C2H2 type ARS2 PF04959.13 KFQ93121.1 - 0.17 12.2 0.1 0.17 12.2 0.1 5.3 5 0 0 5 5 4 0 Arsenite-resistance protein 2 Zn-C2H2_12 PF18112.1 KFQ93121.1 - 0.36 11.3 24.8 2 8.9 0.3 8.3 9 0 0 9 9 8 0 Autophagy receptor zinc finger-C2H2 domain UCH PF00443.29 KFQ93122.1 - 7.5e-26 91.2 1.0 9.2e-26 90.9 1.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFQ93122.1 - 4.4e-05 23.7 0.2 8.4e-05 22.8 0.2 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KFQ93122.1 - 0.00047 19.9 0.1 0.00065 19.4 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Synaptobrevin PF00957.21 KFQ93123.1 - 2.1e-29 101.2 0.6 2.2e-29 101.1 0.6 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF2721 PF11026.8 KFQ93123.1 - 0.0072 16.2 0.1 0.0083 16.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) Sec20 PF03908.13 KFQ93123.1 - 0.01 15.7 1.9 0.014 15.3 1.9 1.4 1 1 0 1 1 1 0 Sec20 SNARE PF05739.19 KFQ93123.1 - 0.01 15.8 0.6 0.025 14.6 0.3 1.8 2 0 0 2 2 2 0 SNARE domain DUF2207 PF09972.9 KFQ93123.1 - 0.032 13.0 0.1 0.032 13.0 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MCU PF04678.13 KFQ93123.1 - 0.037 14.1 0.1 0.039 14.1 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Ferlin_C PF16165.5 KFQ93123.1 - 0.062 13.2 0.1 0.068 13.1 0.1 1.1 1 0 0 1 1 1 0 Ferlin C-terminus Integrase_H2C2 PF17921.1 KFQ93123.1 - 0.068 13.3 1.0 0.11 12.6 1.0 1.4 1 1 0 1 1 1 0 Integrase zinc binding domain EMP24_GP25L PF01105.24 KFQ93123.1 - 0.087 12.8 0.5 0.099 12.6 0.5 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Prominin PF05478.11 KFQ93123.1 - 0.094 10.7 0.2 0.11 10.4 0.2 1.1 1 0 0 1 1 1 0 Prominin S-AdoMet_synt_C PF02773.16 KFQ93124.1 - 2e-49 167.1 0.1 2e-49 167.1 0.1 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KFQ93124.1 - 4.3e-47 159.3 0.0 8.5e-47 158.3 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KFQ93124.1 - 6.8e-35 119.7 0.4 1.6e-34 118.5 0.4 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Histone PF00125.24 KFQ93125.1 - 4.5e-18 65.9 0.0 4.9e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KFQ93125.1 - 0.0065 16.2 0.2 0.014 15.2 0.2 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A SDA1 PF05285.12 KFQ93127.1 - 3.9e-67 227.2 42.2 4.2e-38 131.7 4.9 3.1 2 1 1 3 3 3 3 SDA1 NUC130_3NT PF08158.12 KFQ93127.1 - 5.5e-26 90.6 3.7 1.3e-25 89.4 1.1 3.0 3 0 0 3 3 3 1 NUC130/3NT domain Ribosomal_L22 PF00237.19 KFQ93127.1 - 0.011 15.9 2.0 0.03 14.5 0.5 2.5 2 0 0 2 2 2 0 Ribosomal protein L22p/L17e DUF5616 PF18481.1 KFQ93127.1 - 0.17 12.2 1.5 28 5.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5616) CBAH PF02275.18 KFQ93128.1 - 2.8e-08 33.8 0.0 0.0001 22.1 0.0 2.3 2 1 0 2 2 2 2 Linear amide C-N hydrolases, choloylglycine hydrolase family Metallophos PF00149.28 KFQ93129.1 - 8.7e-26 91.7 0.2 4.4e-20 73.1 0.2 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 KFQ93129.1 - 6.3e-18 65.0 8.6 2.2e-11 44.0 3.5 3.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFQ93129.1 - 5.5e-17 60.0 1.8 5.9e-06 25.5 0.1 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KFQ93129.1 - 9.7e-15 53.2 2.9 0.0016 18.2 0.1 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 KFQ93129.1 - 4.4e-12 45.7 3.1 1.6e-05 24.6 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain pair PPP5 PF08321.12 KFQ93129.1 - 1.2e-10 41.6 0.6 2e-09 37.6 0.0 3.0 2 1 1 3 3 3 1 PPP5 TPR repeat region EF-hand_5 PF13202.6 KFQ93129.1 - 3.1e-09 35.9 4.5 0.00047 19.5 0.0 3.6 3 0 0 3 3 3 2 EF hand IQ PF00612.27 KFQ93129.1 - 0.00012 21.5 2.1 0.00038 20.0 2.1 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif EF-hand_4 PF12763.7 KFQ93129.1 - 0.0019 18.1 5.0 0.18 11.8 0.7 3.1 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFQ93129.1 - 0.12 12.7 0.0 29 5.1 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain Nup54 PF13874.6 KFQ93130.1 - 5.5e-46 156.2 2.4 5.5e-46 156.2 2.4 1.9 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nup54_C PF18437.1 KFQ93130.1 - 3.1e-18 65.4 7.9 3.1e-18 65.4 7.9 2.8 2 0 0 2 2 2 1 Nup54 C-terminal interacting domain XhlA PF10779.9 KFQ93130.1 - 0.077 13.2 1.2 0.26 11.5 1.2 1.9 1 0 0 1 1 1 0 Haemolysin XhlA KRTAP PF11759.8 KFQ93130.1 - 0.086 13.4 12.6 0.22 12.1 12.6 1.7 1 0 0 1 1 1 0 Keratin-associated matrix Regulator_TrmB PF11495.8 KFQ93130.1 - 0.18 10.9 0.8 25 4.0 0.0 2.9 2 1 0 3 3 3 0 Archaeal transcriptional regulator TrmB Keratin_2_head PF16208.5 KFQ93130.1 - 2.2 8.4 20.8 4 7.5 20.8 1.5 1 0 0 1 1 1 0 Keratin type II head TBCC_N PF16752.5 KFQ93130.1 - 7.5 7.0 11.0 1.4 9.4 3.8 3.2 2 1 1 3 3 3 0 Tubulin-specific chaperone C N-terminal domain CD36 PF01130.21 KFQ93131.1 - 1.1e-145 485.8 0.5 1.2e-145 485.6 0.5 1.0 1 0 0 1 1 1 1 CD36 family Gal-bind_lectin PF00337.22 KFQ93132.1 - 3.9e-28 97.6 0.0 4.5e-28 97.4 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin Ank_5 PF13857.6 KFQ93133.1 - 3.6e-11 43.1 0.0 2.3e-08 34.1 0.0 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KFQ93133.1 - 1.9e-07 31.2 0.5 2.9e-05 24.3 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 KFQ93133.1 - 4.9e-07 30.3 0.0 6.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ93133.1 - 2.3e-05 24.8 0.1 0.00011 22.7 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ93133.1 - 6e-05 23.1 0.3 0.015 15.7 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeat Septin PF00735.18 KFQ93134.1 - 7.3e-99 330.6 1.3 7.3e-99 330.6 1.3 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KFQ93134.1 - 5.6e-07 29.6 0.0 5.6e-07 29.6 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF3080 PF11279.8 KFQ93134.1 - 8.8e-05 21.9 6.6 0.00013 21.3 6.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3080) Roc PF08477.13 KFQ93134.1 - 0.0004 20.6 0.0 0.0014 18.8 0.0 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KFQ93134.1 - 0.00046 20.6 0.1 0.0015 18.9 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFQ93134.1 - 0.00047 20.4 0.3 0.0016 18.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain Ras PF00071.22 KFQ93134.1 - 0.0019 17.8 0.0 0.006 16.2 0.0 1.9 1 0 0 1 1 1 1 Ras family AAA_23 PF13476.6 KFQ93134.1 - 0.0075 16.8 21.1 0.22 12.0 0.2 2.5 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KFQ93134.1 - 0.011 15.4 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 KFQ93134.1 - 0.021 14.4 8.8 0.93 9.0 0.1 3.6 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 KFQ93134.1 - 0.029 13.9 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Fzo_mitofusin PF04799.13 KFQ93134.1 - 0.07 12.7 8.1 0.2 11.2 8.1 1.8 1 0 0 1 1 1 0 fzo-like conserved region RsgA_GTPase PF03193.16 KFQ93134.1 - 0.072 13.0 6.7 0.19 11.6 0.0 3.1 3 1 0 3 3 3 0 RsgA GTPase Dynamin_N PF00350.23 KFQ93134.1 - 0.079 13.0 9.7 1.6 8.8 0.1 3.2 2 1 0 2 2 2 0 Dynamin family DUF87 PF01935.17 KFQ93134.1 - 0.24 11.4 7.3 2.1 8.4 0.0 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain ABC_tran PF00005.27 KFQ93134.1 - 0.25 11.9 0.1 0.25 11.9 0.1 2.6 2 2 0 2 2 1 0 ABC transporter Atg14 PF10186.9 KFQ93134.1 - 0.33 10.0 15.1 0.48 9.5 13.6 1.9 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cyclin_N PF00134.23 KFQ93135.1 - 1.2e-23 83.2 0.7 5.4e-23 81.1 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFQ93135.1 - 0.00066 19.8 3.7 0.0016 18.5 1.8 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 KFQ93137.1 - 5.7e-17 61.7 0.4 5.7e-17 61.7 0.4 2.1 1 1 1 2 2 2 1 Cyclin, N-terminal domain IL2RB_N1 PF18707.1 KFQ93137.1 - 0.43 11.2 7.6 0.42 11.2 2.0 2.3 1 1 1 2 2 2 0 Interleukin-2 receptor subunit beta N-terminal domain 1 IL8 PF00048.20 KFQ93138.1 - 1.3e-15 57.2 0.9 1.5e-15 57.1 0.9 1.0 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like IL8 PF00048.20 KFQ93139.1 - 1.6e-15 57.0 0.4 1.7e-15 56.9 0.4 1.0 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like IL8 PF00048.20 KFQ93140.1 - 1.3e-10 41.2 0.7 1.4e-10 41.2 0.7 1.0 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Exo_endo_phos PF03372.23 KFQ93141.1 - 5.2e-22 78.5 0.0 4.1e-21 75.6 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 KFQ93141.1 - 3.3e-12 46.0 12.7 2.5e-11 43.1 10.0 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFQ93141.1 - 2.7e-09 37.1 18.6 1e-07 32.1 3.0 3.5 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFQ93141.1 - 0.014 14.9 0.9 0.029 13.9 0.9 1.5 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 KFQ93141.1 - 0.038 14.1 11.2 3.9 7.8 2.7 4.1 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 KFQ93141.1 - 0.1 13.2 18.5 8.1 7.4 0.1 5.7 5 0 0 5 5 5 0 Leucine Rich Repeat 7tm_4 PF13853.6 KFQ93143.1 - 1.4e-08 34.8 0.1 1.6e-08 34.7 0.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_4 PF13853.6 KFQ93144.1 - 1.2e-58 199.0 15.8 1.5e-58 198.8 15.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ93144.1 - 2.4e-29 102.5 20.2 3.1e-29 102.1 20.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pkinase PF00069.25 KFQ93145.1 - 4.7e-36 124.5 1.6 5.2e-36 124.4 1.6 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ93145.1 - 3e-15 56.2 0.2 3.3e-15 56.1 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFQ93145.1 - 4.6e-05 23.5 0.2 0.036 14.0 0.5 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KFQ93145.1 - 0.0033 16.8 0.1 0.004 16.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 KFQ93145.1 - 0.012 15.7 0.1 0.024 14.8 0.0 1.5 2 0 0 2 2 2 0 ABC1 family FTA2 PF13095.6 KFQ93145.1 - 0.033 13.8 0.5 0.49 10.0 0.0 2.4 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PNP_UDP_1 PF01048.20 KFQ93146.1 - 7.9e-46 156.2 0.0 8.9e-46 156.0 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily NLPC_P60 PF00877.19 KFQ93146.1 - 0.031 14.3 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 NlpC/P60 family DUF4589 PF15252.6 KFQ93148.1 - 1.2e-77 261.3 6.0 1.3e-77 261.1 6.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4589) WH1 PF00568.23 KFQ93149.1 - 4.8e-35 119.8 0.3 9.9e-35 118.8 0.3 1.5 1 0 0 1 1 1 1 WH1 domain TMF_TATA_bd PF12325.8 KFQ93149.1 - 0.00061 20.0 18.6 0.00061 20.0 18.6 2.9 2 1 1 3 3 3 1 TATA element modulatory factor 1 TATA binding HMMR_N PF15905.5 KFQ93149.1 - 0.00099 18.7 23.1 0.00099 18.7 23.1 1.9 2 0 0 2 2 2 1 Hyaluronan mediated motility receptor N-terminal GAS PF13851.6 KFQ93149.1 - 0.0027 17.1 18.5 0.0027 17.1 18.5 2.6 2 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 KFQ93149.1 - 0.0062 16.6 14.7 0.19 11.8 8.3 3.2 1 1 2 3 3 3 1 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 KFQ93149.1 - 0.014 15.7 7.6 0.014 15.7 7.6 3.4 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DMPK_coil PF08826.10 KFQ93149.1 - 0.018 15.1 5.1 0.018 15.1 5.1 3.4 2 1 1 3 3 3 0 DMPK coiled coil domain like PKcGMP_CC PF16808.5 KFQ93149.1 - 0.024 14.5 2.7 0.024 14.5 2.7 3.7 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase IFT57 PF10498.9 KFQ93149.1 - 0.045 12.7 26.1 0.099 11.6 26.0 1.6 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 FUSC PF04632.12 KFQ93149.1 - 0.054 12.0 6.9 0.074 11.6 6.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Nsp1_C PF05064.13 KFQ93149.1 - 0.054 13.3 22.7 0.48 10.2 10.4 2.6 1 1 1 2 2 2 0 Nsp1-like C-terminal region APG6_N PF17675.1 KFQ93149.1 - 0.073 13.6 41.5 0.036 14.6 22.8 3.2 1 1 1 2 2 2 0 Apg6 coiled-coil region ATG16 PF08614.11 KFQ93149.1 - 0.13 12.4 38.5 0.73 10.0 20.4 2.8 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) FPP PF05911.11 KFQ93149.1 - 0.19 9.9 32.4 0.059 11.6 27.1 1.9 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil NPV_P10 PF05531.12 KFQ93149.1 - 0.22 12.0 11.9 0.35 11.4 0.8 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 KFQ93149.1 - 0.27 11.2 20.5 0.029 14.4 8.2 2.8 2 1 1 3 3 3 0 Laminin Domain II Phage_GP20 PF06810.11 KFQ93149.1 - 0.5 10.2 23.7 3.9 7.3 15.6 3.6 1 1 2 3 3 3 0 Phage minor structural protein GP20 HemX PF04375.14 KFQ93149.1 - 0.51 9.6 24.1 0.15 11.3 9.9 2.4 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4164 PF13747.6 KFQ93149.1 - 0.54 10.6 23.5 0.06 13.6 12.1 3.4 2 1 1 3 3 2 0 Domain of unknown function (DUF4164) CALCOCO1 PF07888.11 KFQ93149.1 - 0.68 8.7 32.3 0.074 11.9 26.1 2.4 2 1 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Prominin PF05478.11 KFQ93149.1 - 0.73 7.7 10.6 1.3 6.9 10.6 1.5 1 0 0 1 1 1 0 Prominin FlaC_arch PF05377.11 KFQ93149.1 - 0.75 10.2 16.4 8.5 6.9 1.8 4.3 1 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 KFQ93149.1 - 0.79 9.0 19.6 1.8 7.9 19.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fmp27_WPPW PF10359.9 KFQ93149.1 - 0.83 8.4 16.6 1.4 7.6 15.7 1.8 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF812 PF05667.11 KFQ93149.1 - 1.2 7.9 30.4 2.2 7.0 30.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DivIC PF04977.15 KFQ93149.1 - 1.5 8.6 33.4 0.37 10.6 4.0 4.5 3 2 1 4 4 3 0 Septum formation initiator CENP-F_leu_zip PF10473.9 KFQ93149.1 - 1.6 8.8 36.9 0.11 12.5 26.9 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2968 PF11180.8 KFQ93149.1 - 1.7 8.2 27.4 0.49 10.0 3.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) DHR10 PF18595.1 KFQ93149.1 - 2.4 8.2 41.8 0.79 9.8 20.5 3.6 2 1 2 4 4 4 0 Designed helical repeat protein 10 domain FapA PF03961.13 KFQ93149.1 - 2.5 6.6 19.5 19 3.7 19.2 2.2 1 1 0 1 1 1 0 Flagellar Assembly Protein A kleA_kleC PF17383.2 KFQ93149.1 - 2.5 8.5 8.5 2.4 8.5 1.4 2.9 2 1 0 2 2 2 0 Uncharacterized KorC regulated protein A NAM-associated PF14303.6 KFQ93149.1 - 2.5 8.8 16.6 56 4.4 16.6 2.3 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF3461 PF11944.8 KFQ93149.1 - 2.7 8.1 15.2 0.24 11.5 4.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) DUF948 PF06103.11 KFQ93149.1 - 2.7 8.3 11.5 12 6.3 3.1 3.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF489 PF04356.12 KFQ93149.1 - 3 7.8 10.6 1.2 9.2 6.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF489) Leu_zip PF15294.6 KFQ93149.1 - 3.4 7.1 27.9 1.2 8.6 24.4 2.1 1 1 1 2 2 2 0 Leucine zipper Bacillus_HBL PF05791.11 KFQ93149.1 - 3.5 7.4 19.9 0.79 9.5 5.2 2.7 2 1 1 3 3 2 0 Bacillus haemolytic enterotoxin (HBL) Fzo_mitofusin PF04799.13 KFQ93149.1 - 4 7.0 19.9 4.1 6.9 11.6 2.9 1 1 2 3 3 3 0 fzo-like conserved region Uso1_p115_C PF04871.13 KFQ93149.1 - 4.2 7.7 36.1 0.52 10.7 19.2 3.1 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region XhlA PF10779.9 KFQ93149.1 - 4.8 7.4 18.4 0.69 10.2 3.4 3.5 2 1 0 3 3 3 0 Haemolysin XhlA FTCD_C PF04961.12 KFQ93149.1 - 5.6 6.7 9.6 3.1 7.5 3.7 2.5 2 1 0 2 2 2 0 Formiminotransferase-cyclodeaminase Fib_alpha PF08702.10 KFQ93149.1 - 6.1 7.0 20.7 2.2 8.4 11.4 2.6 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 KFQ93149.1 - 8 6.9 30.7 4.9 7.6 6.7 2.8 1 1 2 3 3 3 0 Fez1 DUF4239 PF14023.6 KFQ93149.1 - 8.5 6.0 8.7 3.3 7.4 5.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4239) OmpH PF03938.14 KFQ93149.1 - 9 6.6 32.5 0.27 11.6 17.9 3.4 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) RVT_1 PF00078.27 KFQ93150.1 - 0.002 17.7 0.0 0.0037 16.8 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) HLH PF00010.26 KFQ93151.1 - 1.1e-17 63.7 0.3 1.4e-17 63.4 0.3 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain COE1_HLH PF16423.5 KFQ93151.1 - 0.017 14.8 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain TRIC PF05197.13 KFQ93152.1 - 1.4e-83 279.2 4.4 1.7e-83 278.9 4.4 1.0 1 0 0 1 1 1 1 TRIC channel UPF0126 PF03458.13 KFQ93152.1 - 0.0077 16.1 5.5 0.33 10.9 0.1 2.7 2 1 0 2 2 2 2 UPF0126 domain XPC-binding PF09280.11 KFQ93153.1 - 4e-26 90.5 19.0 7e-26 89.7 19.0 1.4 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 KFQ93153.1 - 4.2e-26 90.4 2.5 9.8e-14 50.9 0.3 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 KFQ93153.1 - 1.2e-13 50.6 0.3 2.6e-13 49.5 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family UBA_3 PF09288.10 KFQ93153.1 - 0.00043 20.0 0.0 0.011 15.6 0.0 2.3 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.6 KFQ93153.1 - 0.0021 18.1 0.0 0.0037 17.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KFQ93153.1 - 0.04 14.5 0.0 0.082 13.5 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF1421 PF07223.11 KFQ93153.1 - 0.11 12.4 0.0 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 UBA-like domain (DUF1421) UBA_2 PF08587.11 KFQ93153.1 - 0.11 12.6 0.1 0.28 11.3 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) DUF1296 PF06972.11 KFQ93153.1 - 0.11 12.6 0.0 3 8.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) Radical_SAM PF04055.21 KFQ93153.1 - 0.22 11.9 0.0 1.1 9.6 0.0 1.9 2 0 0 2 2 2 0 Radical SAM superfamily STI1 PF17830.1 KFQ93153.1 - 1.7 8.6 6.4 11 6.0 6.3 2.3 1 1 0 1 1 1 0 STI1 domain TFIIA PF03153.13 KFQ93153.1 - 4.5 7.2 10.2 6.6 6.6 10.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C2H2 PF00096.26 KFQ93154.1 - 2.3e-18 65.6 18.7 2.2e-06 27.8 2.8 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ93154.1 - 9.8e-13 47.9 11.1 2.4e-07 30.9 2.9 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ93154.1 - 2.5e-10 40.3 17.0 0.0012 19.5 2.1 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2HE PF16278.5 KFQ93154.1 - 0.011 16.2 5.5 0.7 10.4 1.4 2.4 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_8 PF15909.5 KFQ93154.1 - 0.012 15.8 2.8 0.013 15.7 2.8 1.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 KFQ93154.1 - 0.017 14.9 8.8 2.7 7.8 1.1 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 KFQ93154.1 - 0.019 15.3 8.2 0.58 10.6 0.7 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF3850 PF12961.7 KFQ93154.1 - 0.024 14.7 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) zf-C2H2_jaz PF12171.8 KFQ93154.1 - 0.058 13.7 7.2 1.3 9.4 0.4 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFQ93154.1 - 0.063 13.2 2.9 1.1 9.2 0.3 2.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type FOXP-CC PF16159.5 KFQ93154.1 - 0.2 12.3 8.0 0.42 11.3 1.2 2.8 1 1 2 3 3 3 0 FOXP coiled-coil domain HNH PF01844.23 KFQ93154.1 - 0.73 10.1 6.8 5.7 7.2 0.2 2.7 3 0 0 3 3 3 0 HNH endonuclease zf_C2H2_ZHX PF18387.1 KFQ93154.1 - 6.4 6.5 9.2 4.5 7.0 0.6 2.9 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Glyco_hydro_77 PF02446.17 KFQ93156.1 - 0.029 13.2 0.1 0.036 12.9 0.1 1.1 1 0 0 1 1 1 0 4-alpha-glucanotransferase TPR_1 PF00515.28 KFQ93157.1 - 1.4e-27 94.3 9.5 3.4e-09 36.1 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ93157.1 - 2.2e-22 77.3 5.0 2.9e-06 27.0 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ93157.1 - 1.1e-19 69.9 11.4 1.9e-08 33.9 0.9 4.0 2 1 2 4 4 4 3 TPR repeat TPR_8 PF13181.6 KFQ93157.1 - 3.8e-19 67.2 6.8 1.8e-06 27.7 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat SGTA_dimer PF16546.5 KFQ93157.1 - 7.7e-18 64.0 3.3 3.1e-16 58.9 0.2 3.1 3 0 0 3 3 3 1 Homodimerisation domain of SGTA TPR_17 PF13431.6 KFQ93157.1 - 1.3e-14 53.4 5.2 4.5e-08 32.9 1.4 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ93157.1 - 8.8e-13 47.3 0.2 0.00017 21.4 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ93157.1 - 4e-09 36.6 1.6 5.9e-06 26.5 0.4 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ93157.1 - 5.6e-09 36.1 0.0 0.24 12.3 0.0 3.8 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ93157.1 - 9.1e-09 35.7 1.0 5.4e-05 23.6 0.1 2.6 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFQ93157.1 - 8.9e-08 32.2 0.0 6.5e-05 23.0 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ93157.1 - 2.8e-07 31.1 0.0 0.0025 18.4 0.0 2.3 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ93157.1 - 9.2e-07 28.5 3.6 0.037 13.9 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TOM20_plant PF06552.12 KFQ93157.1 - 5.8e-06 26.2 3.4 0.0024 17.6 0.4 3.3 2 1 1 3 3 3 2 Plant specific mitochondrial import receptor subunit TOM20 Fis1_TPR_C PF14853.6 KFQ93157.1 - 7.5e-05 22.7 4.0 0.12 12.5 0.3 3.3 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.9 KFQ93157.1 - 0.00022 20.6 0.1 0.48 9.9 0.1 3.4 3 0 0 3 3 3 1 SHNi-TPR TPR_6 PF13174.6 KFQ93157.1 - 0.00066 20.2 0.3 0.58 10.9 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 KFQ93157.1 - 0.0035 17.4 8.7 0.3 11.2 0.2 3.5 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain DUF627 PF04781.12 KFQ93157.1 - 0.0063 16.5 2.6 0.075 13.1 0.1 2.6 3 0 0 3 3 2 1 Protein of unknown function (DUF627) TPR_15 PF13429.6 KFQ93157.1 - 0.012 14.9 0.1 0.051 12.8 0.1 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat BTAD PF03704.17 KFQ93157.1 - 0.023 15.2 0.2 0.18 12.2 0.1 2.1 1 1 1 2 2 2 0 Bacterial transcriptional activator domain PrkA PF06798.12 KFQ93157.1 - 0.023 14.3 1.7 0.046 13.3 0.2 2.0 2 1 0 2 2 2 0 PrkA serine protein kinase C-terminal domain ANAPC3 PF12895.7 KFQ93157.1 - 0.093 13.0 2.4 0.32 11.2 2.4 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Occludin_ELL PF07303.13 KFQ93158.1 - 0.13 13.0 0.1 2.8 8.7 0.0 2.2 2 0 0 2 2 2 0 Occludin homology domain Laminin_G_2 PF02210.24 KFQ93160.1 - 2.5e-16 60.4 0.1 3.6e-16 59.9 0.1 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFQ93160.1 - 1.3e-05 25.5 0.2 2.1e-05 24.7 0.2 1.7 1 1 0 1 1 1 1 Laminin G domain Na_trans_cytopl PF11933.8 KFQ93160.1 - 0.059 13.2 0.1 0.084 12.7 0.1 1.1 1 0 0 1 1 1 0 Cytoplasmic domain of voltage-gated Na+ ion channel DUF3439 PF11921.8 KFQ93160.1 - 0.36 10.8 5.4 0.59 10.1 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Syndecan PF01034.20 KFQ93161.1 - 4.3e-08 33.0 0.8 1.1e-07 31.6 0.8 1.8 1 1 0 1 1 1 1 Syndecan domain DUF202 PF02656.15 KFQ93161.1 - 0.015 15.7 0.0 0.023 15.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF202) CD34_antigen PF06365.12 KFQ93161.1 - 0.022 14.4 0.1 0.029 13.9 0.1 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family COX14 PF14880.6 KFQ93161.1 - 0.14 12.0 0.2 0.29 11.0 0.2 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Orf78 PF06024.12 KFQ93161.1 - 2.9 8.2 4.6 0.64 10.4 0.3 1.9 1 1 1 2 2 2 0 Orf78 (ac78) T4_deiodinase PF00837.17 KFQ93162.1 - 5.2e-57 192.9 0.0 5.7e-57 192.7 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase T4_deiodinase PF00837.17 KFQ93163.1 - 3.4e-11 42.9 0.2 3.5e-11 42.9 0.2 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase Glyco_transf_41 PF13844.6 KFQ93164.1 - 0.039 12.4 0.0 0.044 12.2 0.0 1.0 1 0 0 1 1 1 0 Glycosyl transferase family 41 HIP1_clath_bdg PF16515.5 KFQ93166.1 - 0.0022 18.6 41.2 0.0075 16.9 16.6 2.9 1 1 2 3 3 3 2 Clathrin-binding domain of Huntingtin-interacting protein 1 T2SSI PF02501.17 KFQ93166.1 - 0.027 14.6 2.2 2 8.6 0.1 2.9 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein I Acyl-CoA_dh_2 PF08028.11 KFQ93166.1 - 0.16 12.3 1.4 0.58 10.4 1.4 1.9 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain GAS PF13851.6 KFQ93166.1 - 0.43 9.9 42.4 0.074 12.4 19.8 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FPP PF05911.11 KFQ93166.1 - 0.51 8.5 35.8 0.61 8.2 35.8 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil CENP-H PF05837.12 KFQ93166.1 - 0.54 10.7 33.0 0.035 14.5 10.0 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) APG6_N PF17675.1 KFQ93166.1 - 1.1 9.8 42.9 3.5 8.2 16.6 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region ATG16 PF08614.11 KFQ93166.1 - 2.7 8.2 34.3 1.2 9.3 19.3 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Peptidase_C3 PF00548.20 KFQ93166.1 - 8 6.3 8.8 3.2 7.7 3.6 2.0 1 1 1 2 2 2 0 3C cysteine protease (picornain 3C) DUF5036 PF16439.5 KFQ93167.1 - 0.031 14.0 0.0 0.074 12.8 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5036) TMF_TATA_bd PF12325.8 KFQ93167.1 - 0.069 13.4 0.6 0.069 13.4 0.6 4.9 2 1 3 5 5 5 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 KFQ93167.1 - 0.33 11.5 62.3 0.14 12.7 17.6 4.3 2 1 2 4 4 4 0 Apg6 coiled-coil region Syntaxin-6_N PF09177.11 KFQ93167.1 - 1 10.0 36.7 0.71 10.5 7.7 4.5 3 1 1 4 4 4 0 Syntaxin 6, N-terminal Toxin_trans PF07952.12 KFQ93167.1 - 6 5.9 7.0 0.58 9.2 1.1 2.2 3 0 0 3 3 3 0 Clostridium neurotoxin, Translocation domain 7tm_1 PF00001.21 KFQ93168.1 - 2e-37 129.0 19.5 2.7e-37 128.5 19.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.6 KFQ93168.1 - 9.9e-05 22.0 0.9 0.00049 19.8 0.2 2.4 1 1 0 2 2 2 1 Leucine rich repeat LRR_5 PF13306.6 KFQ93168.1 - 0.0064 16.4 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) TFIIA PF03153.13 KFQ93169.1 - 1.4e-91 308.6 76.6 5e-54 184.9 21.8 2.5 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit SelP_N PF04592.14 KFQ93169.1 - 0.012 15.0 7.2 0.012 15.0 7.2 1.7 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF742 PF05331.11 KFQ93169.1 - 1.9 8.3 5.8 0.89 9.4 1.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF742) PTPRCAP PF15713.5 KFQ93169.1 - 9.6 6.5 22.5 2 8.7 1.8 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Stonin2_N PF12016.8 KFQ93170.1 - 2.2e-164 546.9 39.9 3.9e-164 546.0 39.9 1.4 1 0 0 1 1 1 1 Stonin 2 Adap_comp_sub PF00928.21 KFQ93170.1 - 8.5e-60 202.3 0.1 1.8e-59 201.3 0.1 1.5 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Sel1 PF08238.12 KFQ93171.1 - 3.5e-65 215.0 35.3 1.1e-09 38.6 0.5 12.7 13 0 0 13 13 13 11 Sel1 repeat fn2 PF00040.19 KFQ93171.1 - 7.2e-18 64.6 6.4 1.3e-17 63.7 6.4 1.5 1 0 0 1 1 1 1 Fibronectin type II domain SF3A2 PF16835.5 KFQ93171.1 - 0.054 13.9 0.2 2.2 8.7 0.0 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) S6PP_C PF08472.10 KFQ93171.1 - 0.16 11.9 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Sucrose-6-phosphate phosphohydrolase C-terminal SNN_linker PF09050.10 KFQ93171.1 - 0.33 10.8 2.6 25 4.8 0.9 2.7 2 0 0 2 2 2 0 Stannin unstructured linker TPR_16 PF13432.6 KFQ93171.1 - 6.1 7.6 10.0 9.3 7.0 0.9 4.6 3 2 0 3 3 3 0 Tetratricopeptide repeat RVT_1 PF00078.27 KFQ93173.1 - 0.11 12.0 0.1 0.17 11.4 0.0 1.3 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) PX PF00787.24 KFQ93174.1 - 1.5e-19 70.0 1.7 7.1e-19 67.9 1.1 2.1 2 0 0 2 2 2 1 PX domain PXA PF02194.15 KFQ93174.1 - 0.1 12.6 0.2 0.17 11.9 0.2 1.5 1 1 0 1 1 1 0 PXA domain OrfB_IS605 PF01385.19 KFQ93174.1 - 0.2 11.9 1.2 0.51 10.6 0.7 1.8 2 0 0 2 2 2 0 Probable transposase NYD-SP28 PF14772.6 KFQ93174.1 - 2.4 8.2 6.6 1.2 9.2 1.5 2.6 3 0 0 3 3 3 0 Sperm tail Voltage_CLC PF00654.20 KFQ93175.1 - 1.1e-96 324.1 27.4 3.6e-96 322.5 24.8 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KFQ93175.1 - 3.2e-16 59.5 0.2 2.4e-10 40.7 0.0 2.5 2 0 0 2 2 2 2 CBS domain FAM181 PF15238.6 KFQ93176.1 - 9.1e-05 22.4 0.2 0.0001 22.3 0.2 1.2 1 0 0 1 1 1 1 FAM181 LUC7 PF03194.15 KFQ93177.1 - 3.7e-72 243.0 13.5 3.7e-72 243.0 13.5 2.2 1 1 1 2 2 2 1 LUC7 N_terminus TSC22 PF01166.18 KFQ93177.1 - 0.49 10.8 3.8 8.8 6.7 0.2 2.9 2 1 1 3 3 3 0 TSC-22/dip/bun family PQQ_2 PF13360.6 KFQ93178.1 - 0.00036 20.2 0.4 0.011 15.4 0.4 2.9 1 1 0 1 1 1 1 PQQ-like domain FG-GAP PF01839.23 KFQ93178.1 - 0.0035 17.5 2.3 0.44 10.7 0.3 3.4 3 0 0 3 3 3 1 FG-GAP repeat VCBS PF13517.6 KFQ93178.1 - 0.083 13.5 0.9 2.7 8.7 0.3 2.7 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF3413 PF11893.8 KFQ93178.1 - 0.1 11.7 0.3 0.15 11.2 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) RGS_DHEX PF18148.1 KFQ93179.1 - 7.2e-38 128.7 0.4 1.9e-37 127.4 0.4 1.7 1 0 0 1 1 1 1 Regulator of G-protein signalling DHEX domain RGS PF00615.19 KFQ93179.1 - 2.8e-32 111.5 0.1 5.9e-32 110.4 0.1 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 KFQ93179.1 - 3.3e-15 55.9 0.0 7.4e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.22 KFQ93179.1 - 3.4e-10 39.8 0.1 6.8e-08 32.4 0.1 2.5 2 0 0 2 2 2 2 GGL domain Rho_GDI PF02115.17 KFQ93180.1 - 2.5e-62 210.1 0.0 3e-62 209.9 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Thioredoxin PF00085.20 KFQ93181.1 - 1e-47 160.4 0.0 1e-24 86.5 0.0 3.1 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KFQ93181.1 - 1.8e-41 142.1 0.0 9.3e-36 123.5 0.0 2.8 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFQ93181.1 - 3.2e-11 43.3 0.3 0.00026 21.1 0.1 3.1 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KFQ93181.1 - 6.8e-10 39.4 0.0 0.00065 20.1 0.0 3.5 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KFQ93181.1 - 1.5e-08 34.3 0.0 0.00062 19.2 0.0 3.3 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KFQ93181.1 - 9.5e-07 29.1 0.0 0.034 14.5 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 KFQ93181.1 - 7e-06 26.0 0.4 0.069 13.1 0.1 2.8 3 0 0 3 3 3 2 AhpC/TSA family Calsequestrin PF01216.17 KFQ93181.1 - 0.0011 18.2 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Calsequestrin Redoxin PF08534.10 KFQ93181.1 - 0.0016 18.2 0.6 0.78 9.5 0.0 3.3 3 0 0 3 3 3 1 Redoxin Glutaredoxin PF00462.24 KFQ93181.1 - 0.0059 16.8 0.1 0.27 11.5 0.0 2.6 2 0 0 2 2 2 1 Glutaredoxin TraF PF13728.6 KFQ93181.1 - 0.023 14.5 0.0 8.6 6.1 0.0 2.8 2 1 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 KFQ93181.1 - 0.029 14.4 0.0 6.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin domain DIX PF00778.17 KFQ93182.1 - 2.6e-31 107.3 1.1 4.6e-31 106.5 1.1 1.4 1 0 0 1 1 1 1 DIX domain RGS PF00615.19 KFQ93182.1 - 1.1e-27 96.7 0.3 2.2e-27 95.6 0.3 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain AXIN1_TNKS_BD PF16646.5 KFQ93182.1 - 2.1e-25 89.4 3.6 1.3e-24 86.9 3.6 2.5 1 0 0 1 1 1 1 Axin-1 tankyrase binding domain Axin_b-cat_bind PF08833.10 KFQ93182.1 - 7.6e-11 41.9 0.0 3e-10 40.1 0.0 2.1 1 0 0 1 1 1 1 Axin beta-catenin binding domain Cwf_Cwc_15 PF04889.12 KFQ93182.1 - 0.6 9.8 6.1 0.27 10.9 1.1 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ribosomal_L28 PF00830.19 KFQ93183.1 - 2.8e-05 24.2 0.0 4.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal L28 family HNHc_6 PF16784.5 KFQ93183.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative HNHc nuclease DUF3522 PF12036.8 KFQ93184.1 - 1.4e-64 217.9 19.3 1.4e-64 217.9 19.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3522) DUF456 PF04306.13 KFQ93184.1 - 0.27 11.5 5.8 0.53 10.6 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF456) DUF2157 PF09925.9 KFQ93184.1 - 4.5 7.1 9.1 2.5 7.9 3.6 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) Globin PF00042.22 KFQ93185.1 - 1.3e-28 99.7 0.2 1.7e-28 99.3 0.2 1.1 1 0 0 1 1 1 1 Globin ESP PF16590.5 KFQ93185.1 - 0.13 12.5 0.0 0.32 11.3 0.0 1.7 2 0 0 2 2 2 0 Exocrine gland-secreting peptide Globin PF00042.22 KFQ93186.1 - 3.8e-24 85.4 0.1 8.9e-24 84.2 0.0 1.6 2 0 0 2 2 2 1 Globin Globin PF00042.22 KFQ93188.1 - 5.5e-29 101.0 0.0 7.5e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Globin NPR3 PF03666.13 KFQ93189.1 - 8.6e-47 160.0 5.2 2.1e-38 132.3 4.4 2.6 1 1 1 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 KFQ93189.1 - 0.0046 15.8 0.3 0.047 12.4 0.3 2.2 1 1 0 1 1 1 1 Nitrogen permease regulator 2 Pur_DNA_glyco PF02245.16 KFQ93190.1 - 9e-60 201.1 0.0 1.1e-59 200.8 0.0 1.1 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) Rhomboid_SP PF12595.8 KFQ93191.1 - 3e-113 376.5 2.0 4.5e-113 375.9 2.0 1.3 1 0 0 1 1 1 1 Rhomboid serine protease Rhomboid PF01694.22 KFQ93191.1 - 8.7e-28 97.2 9.1 8.7e-28 97.2 9.1 1.8 2 0 0 2 2 2 1 Rhomboid family Herpes_UL56 PF04534.12 KFQ93191.1 - 0.032 13.7 1.2 0.04 13.4 0.2 1.7 2 0 0 2 2 2 0 Herpesvirus UL56 protein B-block_TFIIIC PF04182.12 KFQ93192.1 - 8e-19 67.6 0.0 3.4e-18 65.6 0.0 2.2 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC DUF4457 PF14652.6 KFQ93193.1 - 9.3e-234 774.4 0.3 3.9e-150 499.6 0.0 4.5 3 2 1 4 4 4 4 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 KFQ93193.1 - 1.6e-05 24.9 0.0 4.8 7.2 0.0 5.1 5 0 0 5 5 5 2 Sad1 / UNC-like C-terminal GSG-1 PF07803.11 KFQ93194.1 - 4.9e-51 171.5 0.5 9.7e-51 170.6 0.5 1.5 1 0 0 1 1 1 1 GSG1-like protein PMP22_Claudin PF00822.20 KFQ93194.1 - 1.7e-08 34.6 11.8 1.2e-05 25.3 11.8 2.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFQ93194.1 - 0.00023 21.0 16.1 0.0029 17.4 16.0 2.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction TMEM191C PF15194.6 KFQ93194.1 - 0.22 11.7 0.7 0.38 10.9 0.7 1.4 1 0 0 1 1 1 0 TMEM191C family Tissue_fac PF01108.17 KFQ93195.1 - 7.3e-21 74.0 0.0 3.8e-20 71.7 0.0 2.1 2 0 0 2 2 2 1 Tissue factor Interfer-bind PF09294.10 KFQ93195.1 - 9.3e-11 42.0 0.6 4e-10 39.9 0.6 1.9 1 1 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.21 KFQ93195.1 - 0.0018 18.6 0.1 1.6 9.1 0.1 2.6 2 1 0 2 2 2 2 Fibronectin type III domain Fox-1_C PF12414.8 KFQ93198.1 - 1.9e-43 146.7 22.8 1.9e-43 146.7 22.8 2.6 3 1 0 3 3 3 1 Calcitonin gene-related peptide regulator C terminal RRM_1 PF00076.22 KFQ93198.1 - 1.5e-18 66.3 0.1 3.4e-18 65.2 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPESP1 PF15754.5 KFQ93198.1 - 0.032 13.4 3.2 0.048 12.8 3.2 1.2 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 RRM_5 PF13893.6 KFQ93198.1 - 0.053 13.1 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Claudin_2 PF13903.6 KFQ93200.1 - 3.8e-18 65.9 7.4 4.3e-18 65.8 7.4 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFQ93200.1 - 2.5e-07 30.7 5.3 3.5e-07 30.2 5.3 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family AA_permease_C PF13906.6 KFQ93200.1 - 1.1 9.4 10.0 0.24 11.5 4.4 2.3 2 0 0 2 2 2 0 C-terminus of AA_permease PsbN PF02468.15 KFQ93200.1 - 2 8.3 5.5 0.95 9.4 2.2 2.2 1 1 2 3 3 3 0 Photosystem II reaction centre N protein (psbN) Methyltransf_16 PF10294.9 KFQ93201.1 - 9.6e-21 74.3 0.7 6.5e-19 68.3 0.7 2.2 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KFQ93201.1 - 0.0065 17.2 0.1 0.023 15.4 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFQ93201.1 - 0.02 14.7 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF2321 PF10083.9 KFQ93201.1 - 0.088 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) PrmA PF06325.13 KFQ93201.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TMEM223 PF14640.6 KFQ93202.1 - 5.2e-06 26.7 0.1 6.5e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Transmembrane protein 223 PMM PF03332.13 KFQ93203.1 - 5.6e-111 369.6 1.1 6.3e-111 369.4 1.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase DUF600 PF04634.12 KFQ93203.1 - 0.086 12.9 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF600 CSD PF00313.22 KFQ93204.1 - 3.5e-13 49.2 0.0 4.8e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KFQ93204.1 - 0.0094 15.6 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease B OB domain USP7_ICP0_bdg PF12436.8 KFQ93205.1 - 8.8e-76 254.4 0.0 6.7e-75 251.5 0.0 2.3 2 1 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KFQ93205.1 - 6.2e-65 218.8 4.3 3e-62 210.0 2.8 3.2 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 KFQ93205.1 - 6.7e-50 170.0 0.3 1.2e-49 169.2 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFQ93205.1 - 8.3e-18 65.0 0.0 2.8e-17 63.3 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KFQ93205.1 - 8.9e-16 58.1 1.5 1.3e-14 54.3 0.2 2.9 2 1 1 3 3 3 1 MATH domain DUF4588 PF15251.6 KFQ93206.1 - 1.6e-54 185.3 0.0 1.8e-54 185.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) Pet20 PF08692.10 KFQ93207.1 - 0.0082 16.9 0.2 0.01 16.6 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial protein Pet20 GIT_CC PF16559.5 KFQ93207.1 - 0.017 14.9 0.4 0.036 13.9 0.4 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.12 KFQ93207.1 - 0.06 13.8 4.6 4.1 7.9 4.6 2.2 1 1 0 1 1 1 0 Cell division protein ZapB bZIP_2 PF07716.15 KFQ93207.1 - 0.098 12.8 1.4 0.96 9.6 0.3 2.3 2 0 0 2 2 2 0 Basic region leucine zipper TSC22 PF01166.18 KFQ93207.1 - 0.51 10.7 4.2 2.9 8.3 0.6 2.8 1 1 1 2 2 2 0 TSC-22/dip/bun family bZIP_1 PF00170.21 KFQ93207.1 - 0.55 10.4 4.5 2.9 8.1 1.1 2.3 1 1 1 2 2 2 0 bZIP transcription factor NMDAR2_C PF10565.9 KFQ93208.1 - 3.6e-274 911.7 34.6 4.4e-274 911.5 34.6 1.1 1 0 0 1 1 1 1 N-methyl D-aspartate receptor 2B3 C-terminus Lig_chan PF00060.26 KFQ93208.1 - 1.9e-34 118.6 0.1 1.9e-34 118.6 0.1 2.0 3 0 0 3 3 3 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFQ93208.1 - 8e-31 106.6 0.1 4.3e-30 104.3 0.1 2.1 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFQ93208.1 - 7.1e-21 74.7 0.0 2.5e-20 72.9 0.0 1.8 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 KFQ93208.1 - 3e-06 26.6 0.3 1.4e-05 24.4 0.3 2.1 1 1 0 1 1 1 1 Receptor family ligand binding region PMP22_Claudin PF00822.20 KFQ93209.1 - 1.3e-50 171.5 15.1 1.5e-50 171.4 15.1 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFQ93209.1 - 1.7e-11 44.3 6.4 1.7e-11 44.3 6.4 2.0 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.12 KFQ93209.1 - 4.7e-06 26.4 8.8 4.7e-06 26.4 8.8 3.1 1 1 1 2 2 2 1 SUR7/PalI family Amastin PF07344.11 KFQ93209.1 - 0.00049 20.0 12.3 0.00095 19.0 12.3 1.6 1 1 0 1 1 1 1 Amastin surface glycoprotein Claudin_3 PF06653.11 KFQ93209.1 - 0.0042 17.1 16.1 0.0098 15.8 16.1 1.6 1 1 0 1 1 1 1 Tight junction protein, Claudin-like DUF2721 PF11026.8 KFQ93209.1 - 0.018 15.0 2.1 0.018 15.0 2.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) DUF4064 PF13273.6 KFQ93209.1 - 0.063 13.5 0.8 0.063 13.5 0.8 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF4131 PF13567.6 KFQ93209.1 - 0.13 11.9 0.3 0.13 11.9 0.3 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) HisKA_7TM PF16927.5 KFQ93209.1 - 0.15 12.1 10.3 0.28 11.2 10.3 1.6 1 1 0 1 1 1 0 N-terminal 7TM region of histidine kinase Clc-like PF07062.12 KFQ93209.1 - 0.2 11.1 15.6 0.22 11.0 8.4 2.1 1 1 1 2 2 2 0 Clc-like Cytochrom_B561 PF03188.16 KFQ93209.1 - 0.38 10.9 6.3 0.084 13.0 2.7 1.8 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 DUF5090 PF17009.5 KFQ93209.1 - 0.46 10.4 7.5 0.83 9.6 7.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) 7TMR-DISM_7TM PF07695.11 KFQ93209.1 - 1 9.2 17.4 0.032 14.1 9.2 2.2 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF202 PF02656.15 KFQ93209.1 - 5.7 7.5 10.4 5.5e+02 1.1 10.4 3.0 1 1 0 1 1 1 0 Domain of unknown function (DUF202) LptF_LptG PF03739.14 KFQ93209.1 - 8 5.2 9.5 3.7 6.3 0.0 2.5 2 1 1 3 3 3 0 Lipopolysaccharide export system permease LptF/LptG Tektin PF03148.14 KFQ93210.1 - 6.3e-141 469.6 20.8 7.1e-141 469.4 20.8 1.0 1 0 0 1 1 1 1 Tektin family Vps23_core PF09454.10 KFQ93210.1 - 0.0006 19.7 1.7 0.24 11.4 0.3 2.6 2 0 0 2 2 2 2 Vps23 core domain NpwBP PF12622.7 KFQ93210.1 - 0.15 12.9 0.0 0.32 11.8 0.0 1.6 1 0 0 1 1 1 0 mRNA biogenesis factor YkuI_C PF10388.9 KFQ93210.1 - 0.47 10.3 4.3 2.8 7.7 0.4 2.9 2 1 0 2 2 2 0 EAL-domain associated signalling protein domain DUF4094 PF13334.6 KFQ93210.1 - 0.85 10.1 6.5 0.4 11.1 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) JIP_LZII PF16471.5 KFQ93210.1 - 1.5 9.1 10.7 4.2 7.6 0.3 4.0 4 0 0 4 4 4 0 JNK-interacting protein leucine zipper II Exonuc_VII_L PF02601.15 KFQ93210.1 - 6.5 6.2 13.2 5 6.6 4.2 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit ParA PF10609.9 KFQ93211.1 - 2e-86 289.4 0.0 2.3e-86 289.3 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_31 PF13614.6 KFQ93211.1 - 0.049 13.6 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain PcrB PF01884.17 KFQ93211.1 - 0.082 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 PcrB family AAA_26 PF13500.6 KFQ93211.1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain TF_Zn_Ribbon PF08271.12 KFQ93211.1 - 0.11 12.1 0.1 0.25 10.9 0.1 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Fer4_NifH PF00142.18 KFQ93211.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF846 PF05832.12 KFQ93212.1 - 1.7e-53 180.4 15.1 1.9e-53 180.3 15.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) NACHT PF05729.12 KFQ93214.1 - 7.9e-36 123.5 0.0 1.8e-35 122.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain LRR_6 PF13516.6 KFQ93214.1 - 1.7e-15 55.6 11.6 1.3e-05 24.8 0.1 5.6 5 1 0 5 5 5 4 Leucine Rich repeat NLRC4_HD2 PF17776.1 KFQ93214.1 - 1.2e-12 48.5 1.1 5.5e-12 46.3 1.1 2.3 1 0 0 1 1 1 1 NLRC4 helical domain HD2 LRR_4 PF12799.7 KFQ93214.1 - 1.7e-11 44.1 7.8 9e-07 29.1 0.8 4.8 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFQ93214.1 - 2.2e-08 33.8 0.6 0.0001 21.8 0.1 2.8 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KFQ93214.1 - 4.9e-07 29.4 7.2 0.0025 17.5 2.6 4.7 3 1 1 4 4 4 2 Leucine rich repeat NB-ARC PF00931.22 KFQ93214.1 - 5.6e-06 25.7 0.1 1.8e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain LRR_1 PF00560.33 KFQ93214.1 - 1.5e-05 24.9 1.1 22 6.1 0.0 6.0 5 0 0 5 5 5 0 Leucine Rich Repeat AAA PF00004.29 KFQ93214.1 - 0.0018 18.7 0.0 0.0047 17.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PKS_DE PF18369.1 KFQ93214.1 - 0.0074 16.8 0.8 21 5.8 0.0 3.7 2 1 1 3 3 3 0 Polyketide synthase dimerisation element domain AAA_16 PF13191.6 KFQ93214.1 - 0.045 14.1 0.0 0.21 11.9 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KFQ93214.1 - 0.094 13.0 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFQ93214.1 - 0.15 12.4 0.0 0.41 11.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase LRR_2 PF07723.13 KFQ93214.1 - 2.1 9.2 6.9 7.6 7.4 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat Dexa_ind PF15198.6 KFQ93215.1 - 1.7e-43 146.6 10.6 1.9e-43 146.5 10.6 1.0 1 0 0 1 1 1 1 Dexamethasone-induced FPL PF09758.9 KFQ93216.1 - 1.5e-62 210.0 11.9 3e-62 209.0 11.9 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein SH2 PF00017.24 KFQ93218.1 - 2.2e-10 40.5 0.0 4.1e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.16 KFQ93218.1 - 9.7e-09 35.5 0.0 1.9e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 SOCS box RMI2 PF16100.5 KFQ93219.1 - 3e-21 75.6 0.2 3.2e-21 75.5 0.2 1.0 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 DUF5624 PF18538.1 KFQ93220.1 - 0.063 13.4 0.2 0.19 11.8 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) M-factor PF03855.13 KFQ93220.1 - 0.09 12.9 0.3 6.8 6.9 0.1 2.6 2 0 0 2 2 2 0 M-factor zf-LITAF-like PF10601.9 KFQ93221.1 - 2.3e-26 91.8 11.3 3e-26 91.5 11.3 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain DUF4451 PF14616.6 KFQ93221.1 - 0.046 13.9 0.2 0.24 11.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4451) zf-ACC PF17848.1 KFQ93221.1 - 0.36 10.9 5.6 3.4 7.8 1.3 2.5 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain SNN_transmemb PF09049.10 KFQ93222.1 - 2.9e-23 81.5 8.6 3.7e-23 81.2 8.6 1.1 1 0 0 1 1 1 1 Stannin transmembrane SNN_cytoplasm PF09051.10 KFQ93222.1 - 5.1e-21 74.2 0.4 6.7e-21 73.8 0.4 1.2 1 0 0 1 1 1 1 Stannin cytoplasmic SNN_linker PF09050.10 KFQ93222.1 - 2.1e-20 72.1 2.8 2.9e-20 71.7 2.8 1.2 1 0 0 1 1 1 1 Stannin unstructured linker DUF5337 PF17272.2 KFQ93222.1 - 0.032 14.0 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5337) LapA_dom PF06305.11 KFQ93222.1 - 0.06 13.2 0.1 0.085 12.7 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF202 PF02656.15 KFQ93222.1 - 0.12 12.8 0.5 0.15 12.5 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Thioredoxin PF00085.20 KFQ93223.1 - 1.6e-22 79.5 0.0 2.4e-11 43.5 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 KFQ93223.1 - 5.6e-05 23.1 0.1 0.097 12.6 0.0 3.6 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFQ93223.1 - 9.1e-05 22.6 0.8 0.011 15.9 0.0 3.0 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_8 PF13905.6 KFQ93223.1 - 0.00033 20.9 0.2 0.93 9.9 0.1 3.4 2 0 0 2 2 2 2 Thioredoxin-like DUF836 PF05768.14 KFQ93223.1 - 0.0069 16.8 0.0 0.033 14.6 0.0 2.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 KFQ93223.1 - 0.023 15.1 0.3 5.4 7.5 0.1 3.7 3 1 0 3 3 3 0 Thioredoxin-like domain Macoilin PF09726.9 KFQ93223.1 - 0.033 12.8 14.2 0.049 12.2 14.2 1.3 1 0 0 1 1 1 0 Macoilin family TMF_TATA_bd PF12325.8 KFQ93223.1 - 0.038 14.2 16.5 0.12 12.6 16.5 1.9 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Tho2 PF11262.8 KFQ93223.1 - 0.11 11.6 8.8 0.2 10.8 8.8 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Redoxin PF08534.10 KFQ93223.1 - 0.15 11.8 0.0 5.9 6.6 0.0 2.5 2 0 0 2 2 2 0 Redoxin KASH_CCD PF14662.6 KFQ93223.1 - 0.21 11.4 24.1 0.49 10.2 19.0 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH FUSC PF04632.12 KFQ93223.1 - 0.71 8.3 6.0 1.3 7.4 6.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF641 PF04859.12 KFQ93223.1 - 0.84 10.0 14.5 11 6.4 6.5 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) GPS2_interact PF15784.5 KFQ93223.1 - 1.4 9.4 11.5 0.11 12.9 6.3 1.9 2 0 0 2 2 1 0 G-protein pathway suppressor 2-interacting domain Exonuc_VII_L PF02601.15 KFQ93223.1 - 1.9 8.0 14.0 3 7.3 14.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.14 KFQ93223.1 - 2.6 8.4 15.1 6.5 7.1 15.1 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ATG16 PF08614.11 KFQ93223.1 - 2.7 8.2 29.6 0.12 12.6 22.5 2.1 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Nup54 PF13874.6 KFQ93223.1 - 2.8 8.0 20.2 5.2 7.2 20.2 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 APG6_N PF17675.1 KFQ93223.1 - 4.9 7.7 28.8 0.44 11.1 23.2 1.9 1 1 1 2 2 1 0 Apg6 coiled-coil region DUF4407 PF14362.6 KFQ93223.1 - 5.3 6.3 12.2 9.3 5.5 12.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 KFQ93223.1 - 6.2 4.6 10.9 11 3.7 10.9 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_1 PF00515.28 KFQ93224.1 - 1.7e-06 27.6 3.5 0.052 13.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-CCCH PF00642.24 KFQ93224.1 - 3.7e-05 23.5 1.9 3.7e-05 23.5 1.9 4.3 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TPR_2 PF07719.17 KFQ93224.1 - 0.0003 20.7 1.4 0.89 9.8 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat zf_CCCH_4 PF18345.1 KFQ93224.1 - 0.0003 20.7 2.4 0.0003 20.7 2.4 4.0 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_4 PF18044.1 KFQ93224.1 - 0.00067 19.4 1.8 0.00067 19.4 1.8 5.0 4 0 0 4 4 4 2 CCCH-type zinc finger zf-C2H2_jaz PF12171.8 KFQ93224.1 - 0.0019 18.4 6.7 0.0019 18.4 6.7 2.2 2 0 0 2 2 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFQ93224.1 - 0.024 15.0 1.9 0.024 15.0 1.9 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFQ93224.1 - 0.029 14.7 6.3 0.098 13.1 6.3 2.0 1 0 0 1 1 1 0 Zinc-finger of C2H2 type ANAPC3 PF12895.7 KFQ93224.1 - 0.03 14.6 2.1 0.1 12.9 2.1 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KFQ93224.1 - 0.12 12.6 0.3 0.66 10.3 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ93224.1 - 0.13 12.7 0.7 0.3 11.5 0.7 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ93224.1 - 0.13 12.8 0.4 0.34 11.4 0.4 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ93224.1 - 0.16 12.3 1.5 20 5.6 0.0 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat Phospholip_A2_1 PF00068.19 KFQ93225.1 - 7.1e-35 119.9 15.1 8e-35 119.7 15.1 1.0 1 0 0 1 1 1 1 Phospholipase A2 SAM_1 PF00536.30 KFQ93226.1 - 7.9e-11 42.2 0.0 1.5e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C3HC4_4 PF15227.6 KFQ93226.1 - 3e-08 33.7 12.5 7.5e-08 32.4 12.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KFQ93226.1 - 7.4e-08 32.1 13.8 1.4e-07 31.2 13.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFQ93226.1 - 8.3e-08 31.9 13.3 1.6e-07 31.0 13.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SAM_2 PF07647.17 KFQ93226.1 - 1.5e-06 28.2 0.0 2.8e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C3HC4_3 PF13920.6 KFQ93226.1 - 2.1e-06 27.5 8.1 3.6e-06 26.7 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFQ93226.1 - 4.9e-06 26.5 11.2 1.5e-05 25.0 11.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFQ93226.1 - 3.6e-05 24.0 14.6 7.4e-05 23.0 14.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 KFQ93226.1 - 0.019 14.7 5.0 0.019 14.7 5.0 2.6 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain DUF1435 PF07256.12 KFQ93226.1 - 0.022 14.9 0.7 0.37 10.9 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1435) zf-ANAPC11 PF12861.7 KFQ93226.1 - 0.026 14.5 4.6 0.06 13.4 4.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SAM_PNT PF02198.16 KFQ93226.1 - 0.031 14.2 0.2 0.085 12.8 0.2 1.7 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain zf-RING_5 PF14634.6 KFQ93226.1 - 0.033 14.1 11.5 0.073 13.0 11.5 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 KFQ93226.1 - 0.056 13.7 11.0 0.12 12.7 11.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFQ93226.1 - 0.068 13.1 10.3 0.16 11.9 10.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KFQ93226.1 - 0.092 12.9 6.6 0.24 11.5 6.6 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 CAF1 PF04857.20 KFQ93227.1 - 6.6e-79 265.4 1.9 6.6e-79 265.4 1.9 1.7 2 0 0 2 2 2 1 CAF1 family ribonuclease RNA_bind PF08675.11 KFQ93227.1 - 1.1e-33 115.1 0.2 2.1e-33 114.2 0.2 1.5 1 0 0 1 1 1 1 RNA binding domain R3H PF01424.22 KFQ93227.1 - 1.3e-06 28.2 0.0 4e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 R3H domain NCBP3 PF10309.9 KFQ93227.1 - 0.012 15.5 0.1 0.028 14.3 0.1 1.6 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 RRM_1 PF00076.22 KFQ93227.1 - 0.027 14.3 0.0 0.069 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VIT PF08487.10 KFQ93227.1 - 0.041 14.1 1.9 0.42 10.8 0.0 2.7 2 0 0 2 2 2 0 Vault protein inter-alpha-trypsin domain LUD_dom PF02589.15 KFQ93227.1 - 0.075 12.7 0.1 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 LUD domain ECH_1 PF00378.20 KFQ93228.1 - 2.6e-75 253.0 0.0 3.3e-75 252.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFQ93228.1 - 7e-14 52.1 0.0 8.8e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase YwhD PF08741.10 KFQ93228.1 - 0.01 15.5 0.3 0.018 14.7 0.3 1.3 1 0 0 1 1 1 0 YwhD family Exo_endo_phos PF03372.23 KFQ93229.1 - 1.5e-10 41.0 0.0 2e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DELLA PF12041.8 KFQ93229.1 - 0.12 12.3 0.1 0.33 10.9 0.1 1.7 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal Exo_endo_phos PF03372.23 KFQ93230.1 - 4e-12 46.2 0.1 4.9e-12 45.9 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KFQ93230.1 - 0.084 12.7 0.0 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase DUF4507 PF14964.6 KFQ93231.1 - 4e-129 430.6 0.7 4.7e-129 430.4 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4507) Acetyltransf_1 PF00583.25 KFQ93232.1 - 2.1e-14 53.8 0.0 2.9e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFQ93232.1 - 1.6e-08 34.9 0.0 2.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFQ93232.1 - 2.1e-08 34.2 0.1 1.3e-07 31.6 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFQ93232.1 - 1.4e-06 28.1 0.0 2.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Nudix_hydro PF18290.1 KFQ93232.1 - 0.0062 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Nudix hydrolase domain zf-C3HC4_3 PF13920.6 KFQ93233.1 - 1.8e-14 53.3 9.4 2.8e-14 52.7 9.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFQ93233.1 - 9e-07 28.7 10.2 1.6e-06 27.9 10.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KFQ93233.1 - 7.6e-06 26.2 11.7 1.3e-05 25.4 11.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFQ93233.1 - 0.0005 20.0 9.5 0.00089 19.2 9.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFQ93233.1 - 0.0017 18.2 11.3 0.003 17.4 11.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KFQ93233.1 - 1.9 8.3 8.3 3.3 7.6 8.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 KFQ93233.1 - 8.4 6.1 13.0 23 4.7 13.0 1.7 1 1 0 1 1 1 0 P-11 zinc finger Cytochrom_B562 PF07361.11 KFQ93236.1 - 0.087 13.5 0.2 0.1 13.3 0.2 1.1 1 0 0 1 1 1 0 Cytochrome b562 zf-LITAF-like PF10601.9 KFQ93237.1 - 7.5e-24 83.8 16.3 1e-23 83.4 16.3 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Heme_oxygenase PF01126.20 KFQ93238.1 - 2.3e-82 275.7 5.0 2.8e-82 275.5 5.0 1.1 1 0 0 1 1 1 1 Heme oxygenase zf-H2C2_2 PF13465.6 KFQ93239.1 - 1.3e-70 230.8 55.1 1.9e-10 40.7 0.7 8.7 9 0 0 9 9 8 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ93239.1 - 4.4e-51 168.6 52.2 1.3e-07 31.7 0.5 8.4 8 1 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ93239.1 - 2.8e-31 105.5 52.6 0.0008 20.0 0.6 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFQ93239.1 - 3.9e-18 65.0 58.7 0.00027 20.9 0.6 9.7 8 2 0 8 8 8 7 C2H2-type zinc finger zf_UBZ PF18439.1 KFQ93239.1 - 8.6e-18 63.6 28.6 0.056 13.0 0.1 8.1 8 0 0 8 8 8 6 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 KFQ93239.1 - 1.2e-16 60.5 15.3 0.016 15.5 0.0 8.0 8 0 0 8 8 8 3 Zinc-finger double-stranded RNA-binding XPA_N PF01286.18 KFQ93239.1 - 7.2e-12 45.1 27.9 0.83 9.7 0.3 8.2 8 0 0 8 8 8 5 XPA protein N-terminal Zn-ribbon_8 PF09723.10 KFQ93239.1 - 1.8e-10 40.8 41.4 0.023 14.8 4.0 7.1 1 1 6 8 8 8 7 Zinc ribbon domain zf-C2H2_11 PF16622.5 KFQ93239.1 - 1.4e-09 37.5 44.3 0.074 12.8 0.3 8.1 8 0 0 8 8 8 6 zinc-finger C2H2-type zf-LYAR PF08790.11 KFQ93239.1 - 1.7e-08 34.2 26.4 0.41 10.6 0.1 8.2 8 0 0 8 8 8 3 LYAR-type C2HC zinc finger zf-trcl PF13451.6 KFQ93239.1 - 2.1e-08 33.9 23.9 2 8.3 0.2 8.1 8 0 0 8 8 8 1 Probable zinc-ribbon domain DNA_RNApol_7kD PF03604.13 KFQ93239.1 - 3.1e-08 33.1 25.7 1.4 8.6 0.3 8.1 8 0 0 8 8 8 2 DNA directed RNA polymerase, 7 kDa subunit CpXC PF14353.6 KFQ93239.1 - 3.4e-07 30.3 19.7 2.3 8.3 0.1 7.8 2 2 3 7 7 7 1 CpXC protein C1_1 PF00130.22 KFQ93239.1 - 5.7e-07 29.3 29.3 0.24 11.3 1.9 6.9 1 1 7 8 8 8 3 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_4 PF13717.6 KFQ93239.1 - 8.5e-07 28.8 22.2 1.7 8.6 0.0 7.6 6 2 1 7 7 7 2 zinc-ribbon domain DZR PF12773.7 KFQ93239.1 - 9.6e-07 28.7 29.0 1.8e+04 -7.8 29.0 4.8 1 1 0 1 1 0 0 Double zinc ribbon FYDLN_acid PF09538.10 KFQ93239.1 - 1.8e-06 28.6 15.3 14 6.4 0.0 7.6 1 1 7 8 8 8 0 Protein of unknown function (FYDLN_acid) YhfH PF14149.6 KFQ93239.1 - 2e-06 27.7 32.3 3.2 7.8 0.2 8.1 8 0 0 8 8 8 1 YhfH-like protein zinc_ribbon_15 PF17032.5 KFQ93239.1 - 3.3e-06 27.7 23.8 0.22 12.3 1.9 4.2 1 1 3 4 4 4 3 zinc-ribbon family ADK_lid PF05191.14 KFQ93239.1 - 5.4e-06 26.3 16.6 1.2 9.2 0.9 6.6 3 2 3 6 6 6 1 Adenylate kinase, active site lid TFIIS_C PF01096.18 KFQ93239.1 - 1e-05 25.2 31.0 7.7 6.5 0.2 8.0 7 1 0 7 7 7 0 Transcription factor S-II (TFIIS) zf-AN1 PF01428.16 KFQ93239.1 - 1.5e-05 25.1 32.7 7.8 6.8 0.3 8.2 7 1 1 8 8 8 0 AN1-like Zinc finger C1_4 PF07975.12 KFQ93239.1 - 2.9e-05 24.2 28.5 0.15 12.3 3.1 5.2 2 2 4 6 6 6 3 TFIIH C1-like domain LIM PF00412.22 KFQ93239.1 - 6.6e-05 23.0 28.1 1.5 9.1 2.0 6.3 1 1 5 7 7 7 2 LIM domain DUF2256 PF10013.9 KFQ93239.1 - 6.7e-05 22.9 18.0 2.2 8.5 0.3 7.9 8 0 0 8 8 8 1 Uncharacterized protein conserved in bacteria (DUF2256) zf_C2H2_ZHX PF18387.1 KFQ93239.1 - 9.1e-05 22.0 35.5 0.25 11.0 0.2 7.8 1 1 7 8 8 8 2 Zinc-fingers and homeoboxes C2H2 finger domain Zn_ribbon_recom PF13408.6 KFQ93239.1 - 0.00017 22.1 24.0 2.6 8.6 1.4 6.4 1 1 6 7 7 7 1 Recombinase zinc beta ribbon domain Zn_Tnp_IS1595 PF12760.7 KFQ93239.1 - 0.0012 18.7 39.2 0.41 10.7 3.5 6.0 4 2 0 5 5 5 1 Transposase zinc-ribbon domain zf-met PF12874.7 KFQ93239.1 - 0.0027 18.0 36.1 0.22 11.9 0.6 8.2 8 0 0 8 8 8 1 Zinc-finger of C2H2 type HalOD2 PF18547.1 KFQ93239.1 - 0.0035 17.2 24.3 0.35 10.8 1.0 6.8 4 2 2 6 6 6 2 Halobacterial output domain 2 DUF3268 PF11672.8 KFQ93239.1 - 0.014 15.8 20.3 2.1 8.7 0.7 4.5 1 1 6 7 7 7 0 zinc-finger-containing domain DUF3656 PF12392.8 KFQ93239.1 - 0.025 15.2 0.1 9.5 6.9 0.0 4.1 2 1 3 5 5 3 0 Collagenase Siva PF05458.12 KFQ93239.1 - 0.025 14.3 15.3 0.7 9.6 2.2 3.3 1 1 3 4 4 4 0 Cd27 binding protein (Siva) zf-C2HE PF16278.5 KFQ93239.1 - 0.025 15.0 37.5 6.9 7.2 0.8 8.0 1 1 6 7 7 7 0 C2HE / C2H2 / C2HC zinc-binding finger Elf1 PF05129.13 KFQ93239.1 - 0.082 13.0 25.9 0.87 9.7 0.7 5.1 1 1 4 5 5 5 0 Transcription elongation factor Elf1 like DUF2072 PF09845.9 KFQ93239.1 - 0.1 12.9 25.0 30 4.9 0.1 7.5 8 0 0 8 8 8 0 Zn-ribbon containing protein zf-Mss51 PF13824.6 KFQ93239.1 - 0.58 10.3 45.0 1.2 9.3 0.7 7.8 1 1 6 7 7 7 0 Zinc-finger of mitochondrial splicing suppressor 51 HNH PF01844.23 KFQ93239.1 - 0.63 10.3 32.7 6.7 7.0 0.1 7.9 8 0 0 8 8 8 0 HNH endonuclease Raffinose_syn PF05691.12 KFQ93239.1 - 0.64 7.7 2.8 16 3.1 0.1 3.0 1 1 1 3 3 3 0 Raffinose synthase or seed imbibition protein Sip1 Rubredoxin_2 PF18073.1 KFQ93239.1 - 0.73 9.6 46.4 5.4 6.8 0.5 8.1 8 0 0 8 8 8 0 Rubredoxin metal binding domain zinc-ribbons_6 PF07191.12 KFQ93239.1 - 0.97 9.5 29.2 9.7e+02 -0.1 11.1 6.2 1 1 1 2 2 2 0 zinc-ribbons zf-ribbon_3 PF13248.6 KFQ93239.1 - 1.3 8.6 28.7 10 5.7 0.1 7.7 8 0 0 8 8 8 0 zinc-ribbon domain Yippee-Mis18 PF03226.14 KFQ93239.1 - 2.7 8.3 24.3 1.3 9.3 1.4 5.6 2 2 2 4 4 4 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Scramblase PF03803.15 KFQ93239.1 - 4.3 6.6 4.6 13 5.0 0.2 2.5 1 1 3 4 4 4 0 Scramblase Zn_ribbon_SprT PF17283.2 KFQ93239.1 - 4.9 7.1 26.5 5.8 6.9 0.4 6.6 6 2 0 6 6 6 0 SprT-like zinc ribbon domain zf-Paramyx-P PF13008.7 KFQ93239.1 - 8.3 6.0 29.0 21 4.7 0.1 7.5 8 0 0 8 8 8 0 Zinc-binding domain of Paramyxoviridae V protein Slx4 PF09494.10 KFQ93240.1 - 3.4e-16 58.9 0.0 5.5e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Slx4 endonuclease SAP PF02037.27 KFQ93240.1 - 0.14 11.9 0.9 1.4 8.8 0.2 2.2 2 0 0 2 2 2 0 SAP domain BTB PF00651.31 KFQ93241.1 - 6.8e-11 42.4 0.0 1.2e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain HSP90 PF00183.18 KFQ93242.1 - 5.2e-101 339.1 6.1 9.3e-96 321.8 2.1 2.2 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 KFQ93242.1 - 2.6e-11 43.5 0.0 9.8e-11 41.6 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KFQ93242.1 - 2e-08 34.7 0.2 3.6e-08 33.9 0.2 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Guanylate_cyc PF00211.20 KFQ93243.1 - 2.5e-52 177.2 0.0 3.9e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 KFQ93244.1 - 1e-62 211.0 0.2 1.5e-62 210.5 0.2 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF512 PF04459.12 KFQ93244.1 - 0.028 13.7 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF512) DUF2207 PF09972.9 KFQ93244.1 - 0.067 11.9 0.6 1.6 7.4 0.3 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) AC_N PF16214.5 KFQ93244.1 - 0.34 10.0 0.0 0.34 10.0 0.0 2.9 4 0 0 4 4 4 0 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF2157 PF09925.9 KFQ93244.1 - 7.1 6.4 8.6 70 3.2 8.2 2.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) Dynamin_N PF00350.23 KFQ93245.1 - 1.5e-14 54.4 0.0 7.2e-13 48.9 0.0 2.6 2 1 0 2 2 2 1 Dynamin family EHD_N PF16880.5 KFQ93245.1 - 7.7e-11 41.7 0.0 2.2e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 N-terminal EH-domain containing protein MMR_HSR1 PF01926.23 KFQ93245.1 - 1.6e-08 34.6 0.0 3.9e-08 33.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFQ93245.1 - 0.0011 19.0 0.0 0.21 11.5 0.0 3.4 4 0 0 4 4 4 1 RsgA GTPase Roc PF08477.13 KFQ93245.1 - 0.086 13.1 0.0 9.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KFQ93245.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain HLH PF00010.26 KFQ93246.1 - 6.5e-08 32.4 0.2 5.9e-07 29.3 0.1 2.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4940 PF16298.5 KFQ93246.1 - 0.23 11.1 3.9 0.41 10.3 2.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4940) Lzipper-MIP1 PF14389.6 KFQ93246.1 - 1.7 9.0 23.5 5.4 7.4 16.6 3.8 3 1 1 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 Pam16 PF03656.13 KFQ93247.1 - 7.2e-54 181.2 2.8 7.9e-54 181.1 2.8 1.0 1 0 0 1 1 1 1 Pam16 Integrase_Zn PF02022.19 KFQ93247.1 - 0.19 11.7 3.2 5.7 7.0 0.3 2.4 2 0 0 2 2 2 0 Integrase Zinc binding domain WD40_4 PF16300.5 KFQ93248.1 - 2.1e-16 59.5 0.0 3.7e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KFQ93248.1 - 4.9e-15 55.6 0.0 0.00013 22.7 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF1899 PF08953.11 KFQ93248.1 - 2e-10 40.4 0.0 3.7e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) ANAPC4_WD40 PF12894.7 KFQ93248.1 - 9.2e-07 29.1 0.0 0.018 15.3 0.0 2.8 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KFQ93248.1 - 0.16 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 KFQ93249.1 - 2.4e-13 50.3 2.7 2.3e-05 25.1 0.1 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ93249.1 - 7.8e-06 26.1 0.0 0.00014 22.1 0.0 2.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1899 PF08953.11 KFQ93249.1 - 0.00044 20.1 0.1 0.0018 18.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) DnaJ_C PF01556.18 KFQ93250.1 - 5.1e-26 91.5 0.2 7.2e-26 91.0 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFQ93250.1 - 1.4e-24 85.9 4.1 2.5e-24 85.1 4.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KFQ93250.1 - 1.7e-11 44.3 16.3 3.8e-11 43.2 16.3 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KFQ93250.1 - 0.069 13.1 13.6 0.82 9.7 1.9 3.3 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein RseC_MucC PF04246.12 KFQ93250.1 - 2.7 8.0 4.1 0.64 10.0 0.1 1.8 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF2318 PF10080.9 KFQ93250.1 - 3.8 7.7 7.6 5 7.3 1.3 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) LRR_6 PF13516.6 KFQ93251.1 - 5.2e-53 172.6 39.5 6.9e-06 25.7 0.0 15.0 14 0 0 14 14 14 12 Leucine Rich repeat NACHT PF05729.12 KFQ93251.1 - 6.6e-29 100.9 0.0 1.6e-28 99.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain NLRC4_HD2 PF17776.1 KFQ93251.1 - 7.8e-24 84.7 0.6 7.8e-24 84.7 0.6 2.2 2 0 0 2 2 2 1 NLRC4 helical domain HD2 NOD2_WH PF17779.1 KFQ93251.1 - 8.6e-16 58.0 2.4 1.9e-15 56.9 1.1 2.4 2 0 0 2 2 2 1 NOD2 winged helix domain LRR_1 PF00560.33 KFQ93251.1 - 4.2e-05 23.5 11.9 59 4.8 0.0 9.5 10 1 0 10 10 9 0 Leucine Rich Repeat LRR_4 PF12799.7 KFQ93251.1 - 0.0011 19.4 37.8 0.015 15.7 0.5 8.5 7 2 1 9 9 9 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFQ93251.1 - 0.0015 18.2 44.3 2.6 7.9 6.5 9.5 3 2 5 9 9 9 5 Leucine rich repeat FISNA PF14484.6 KFQ93251.1 - 0.0019 18.4 0.1 0.0093 16.2 0.0 2.1 2 0 0 2 2 2 1 Fish-specific NACHT associated domain DUF5474 PF17568.2 KFQ93251.1 - 0.011 15.8 0.0 0.044 13.8 0.0 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5474) KCT2 PF17818.1 KFQ93251.1 - 0.18 11.9 0.1 0.37 10.9 0.1 1.5 1 0 0 1 1 1 0 Keratinocyte-associated gene product IFT43 PF15305.6 KFQ93251.1 - 0.18 11.9 0.0 0.44 10.7 0.0 1.6 1 0 0 1 1 1 0 Intraflagellar transport protein 43 FAM25 PF15825.5 KFQ93251.1 - 0.84 10.0 2.7 30 5.0 0.0 4.1 4 0 0 4 4 4 0 FAM25 family ABC_tran PF00005.27 KFQ93251.1 - 1.2 9.7 7.3 1.8 9.0 0.0 4.0 5 0 0 5 5 4 0 ABC transporter Cluap1 PF10234.9 KFQ93252.1 - 4.2e-115 383.8 13.4 6e-115 383.2 13.4 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 SseC PF04888.12 KFQ93252.1 - 0.0001 22.0 4.4 0.00017 21.3 4.4 1.4 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family DUF4349 PF14257.6 KFQ93252.1 - 0.1 12.0 4.1 0.43 10.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) RasGAP_C PF03836.15 KFQ93252.1 - 0.22 11.6 10.7 0.73 10.0 10.5 1.8 1 1 0 1 1 1 0 RasGAP C-terminus Ank_2 PF12796.7 KFQ93253.1 - 2.8e-40 136.8 2.1 2.2e-14 53.8 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFQ93253.1 - 4.9e-29 99.5 2.8 9.7e-06 25.8 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 KFQ93253.1 - 2.2e-27 92.1 0.5 8e-05 22.8 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KFQ93253.1 - 4.4e-24 84.2 0.9 3.2e-08 33.7 0.0 4.8 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFQ93253.1 - 4.5e-23 81.3 0.1 1.2e-08 35.3 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) SAM_1 PF00536.30 KFQ93253.1 - 1.1e-12 48.2 0.0 2.1e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFQ93253.1 - 4.3e-12 46.0 0.0 9.2e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 KFQ93253.1 - 0.059 13.5 0.1 0.27 11.4 0.0 2.0 2 0 0 2 2 2 0 IGR protein motif YlqD PF11068.8 KFQ93253.1 - 0.094 13.1 3.8 0.17 12.2 3.8 1.3 1 0 0 1 1 1 0 YlqD protein FH2 PF02181.23 KFQ93253.1 - 0.3 10.2 1.7 0.56 9.3 1.7 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain DUF4701 PF15773.5 KFQ93254.1 - 1.2e-17 64.2 10.8 1.4e-17 63.9 10.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4701) RHH_5 PF07878.11 KFQ93254.1 - 0.061 13.2 0.1 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 UPF0242 PF06785.11 KFQ93254.1 - 0.54 10.3 5.7 0.68 10.0 5.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MAT1 PF06391.13 KFQ93254.1 - 0.67 9.7 8.3 1 9.2 8.3 1.3 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Pkinase PF00069.25 KFQ93256.1 - 5.4e-53 180.1 0.0 6.7e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ93256.1 - 6.8e-30 104.2 0.0 7.6e-30 104.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ93256.1 - 3.8e-07 29.7 0.0 5.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFQ93256.1 - 0.001 18.4 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFQ93256.1 - 0.0011 19.0 0.0 0.26 11.2 0.1 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KFQ93256.1 - 0.016 14.2 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Xpo1 PF08389.12 KFQ93257.1 - 1.2e-23 83.9 18.4 3.7e-22 79.0 0.1 6.6 6 1 0 6 6 6 2 Exportin 1-like protein IBN_N PF03810.19 KFQ93257.1 - 3.2e-09 36.6 1.7 2.1e-08 33.9 0.0 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain adh_short_C2 PF13561.6 KFQ93258.1 - 1.2e-46 159.1 0.0 1.5e-46 158.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFQ93258.1 - 1.3e-33 116.1 0.0 1.7e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFQ93258.1 - 0.0006 19.8 0.1 0.0008 19.4 0.1 1.2 1 0 0 1 1 1 1 KR domain EF-hand_7 PF13499.6 KFQ93259.1 - 2.6e-10 40.6 0.0 5.1e-10 39.7 0.0 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFQ93259.1 - 7.2e-10 37.7 0.0 0.00014 21.2 0.0 2.1 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFQ93259.1 - 1.2e-09 37.9 0.8 0.00047 19.9 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFQ93259.1 - 9.5e-09 34.5 0.1 3.7e-05 23.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFQ93259.1 - 1.9e-05 24.0 0.2 0.00033 20.0 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 KFQ93259.1 - 0.00019 21.7 0.0 0.00029 21.1 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain Sigma54_CBD PF04963.13 KFQ93259.1 - 0.26 11.1 0.0 0.29 11.0 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain UPF0242 PF06785.11 KFQ93260.1 - 0.001 19.2 8.7 0.0012 19.0 8.7 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF4686 PF15742.5 KFQ93260.1 - 0.0016 17.7 16.2 0.0017 17.5 16.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) PspA_IM30 PF04012.12 KFQ93260.1 - 0.025 14.2 12.9 0.029 13.9 12.9 1.1 1 0 0 1 1 1 0 PspA/IM30 family bZIP_1 PF00170.21 KFQ93260.1 - 0.064 13.4 17.7 0.052 13.7 5.0 3.7 1 1 2 3 3 3 0 bZIP transcription factor FlaC_arch PF05377.11 KFQ93260.1 - 0.075 13.4 8.0 0.4 11.1 0.1 3.1 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) HAP1_N PF04849.13 KFQ93260.1 - 0.12 11.6 19.9 0.46 9.6 18.9 1.9 1 1 1 2 2 2 0 HAP1 N-terminal conserved region GRDP-like PF07173.12 KFQ93260.1 - 0.17 12.6 2.9 0.21 12.2 2.9 1.2 1 0 0 1 1 1 0 Glycine-rich domain-containing protein-like TSC22 PF01166.18 KFQ93260.1 - 0.18 12.1 0.4 0.18 12.1 0.4 3.4 1 1 2 3 3 3 0 TSC-22/dip/bun family DUF4446 PF14584.6 KFQ93260.1 - 0.2 11.7 0.1 0.2 11.7 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF4200 PF13863.6 KFQ93260.1 - 0.27 11.6 16.8 0.35 11.3 16.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Sipho_Gp157 PF05565.11 KFQ93260.1 - 0.45 10.5 12.6 2.4 8.2 11.8 1.9 1 1 1 2 2 2 0 Siphovirus Gp157 Vac_Fusion PF02346.16 KFQ93260.1 - 0.53 9.9 7.5 4.6 6.9 0.1 3.1 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 Spc7 PF08317.11 KFQ93260.1 - 0.59 8.9 17.1 0.69 8.7 17.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 KFQ93260.1 - 0.65 10.5 24.0 3.8 8.0 17.3 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region AAA_23 PF13476.6 KFQ93260.1 - 0.66 10.5 13.5 0.82 10.1 13.5 1.1 1 0 0 1 1 1 0 AAA domain DUF848 PF05852.11 KFQ93260.1 - 0.75 9.9 13.9 1.4 9.0 9.6 2.2 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) FapA PF03961.13 KFQ93260.1 - 0.78 8.3 7.8 0.99 7.9 7.8 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A ADIP PF11559.8 KFQ93260.1 - 1.1 9.4 18.8 0.28 11.2 3.5 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Exonuc_VII_L PF02601.15 KFQ93260.1 - 1.5 8.3 8.8 1.7 8.1 8.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HlyD_2 PF12700.7 KFQ93260.1 - 1.6 7.4 9.0 1.9 7.1 9.0 1.1 1 0 0 1 1 1 0 HlyD family secretion protein YabA PF06156.13 KFQ93260.1 - 1.9 9.2 14.6 15 6.3 9.7 2.2 1 1 1 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 KFQ93260.1 - 2.8 8.4 22.4 1.1 9.7 0.6 2.9 1 1 1 2 2 2 0 Cell division protein ZapB GIT_CC PF16559.5 KFQ93260.1 - 3.1 7.7 12.8 0.65 9.9 5.9 2.6 1 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor YebO PF13974.6 KFQ93260.1 - 3.3 7.9 12.0 7.1 6.8 11.0 2.1 1 1 1 2 2 2 0 YebO-like protein SlyX PF04102.12 KFQ93260.1 - 4.1 8.1 15.1 1.2 9.8 4.7 2.6 1 1 1 2 2 2 0 SlyX FUSC PF04632.12 KFQ93260.1 - 4.2 5.8 5.3 5.1 5.5 5.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMPIT PF07851.13 KFQ93260.1 - 4.4 6.4 7.7 6.1 6.0 7.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF5446 PF17522.2 KFQ93260.1 - 5.6 7.2 14.9 1.6 9.0 7.8 2.7 1 1 1 2 2 2 0 Family of unknown function (DUF5446) VGPC1_C PF16799.5 KFQ93260.1 - 9.7 6.3 21.4 0.47 10.5 11.6 2.7 2 1 1 3 3 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Septin PF00735.18 KFQ93261.1 - 4.8e-112 373.8 0.2 5.6e-112 373.6 0.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFQ93261.1 - 1e-07 32.0 0.3 2.3e-07 30.9 0.3 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFQ93261.1 - 1.9e-06 27.9 1.2 2.6e-05 24.2 0.4 2.2 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KFQ93261.1 - 2.2e-05 23.9 0.1 3.4e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 KFQ93261.1 - 0.0003 20.4 0.2 0.23 11.0 0.1 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Roc PF08477.13 KFQ93261.1 - 0.00037 20.7 0.2 0.00071 19.8 0.2 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KFQ93261.1 - 0.00045 20.7 0.0 0.0051 17.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KFQ93261.1 - 0.0013 18.2 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Dynamin_N PF00350.23 KFQ93261.1 - 0.0019 18.3 1.9 0.1 12.7 0.9 2.3 1 1 1 2 2 2 1 Dynamin family IIGP PF05049.13 KFQ93261.1 - 0.003 16.7 0.9 0.067 12.2 0.1 2.5 3 0 0 3 3 3 1 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 KFQ93261.1 - 0.0037 17.5 0.0 0.0093 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.12 KFQ93261.1 - 0.0037 16.6 0.6 0.27 10.5 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Ras PF00071.22 KFQ93261.1 - 0.0041 16.7 0.1 0.0089 15.6 0.1 1.6 1 0 0 1 1 1 1 Ras family ABC_tran PF00005.27 KFQ93261.1 - 0.011 16.3 0.8 0.026 15.0 0.7 1.9 1 1 0 1 1 1 0 ABC transporter AAA_32 PF13654.6 KFQ93261.1 - 0.021 13.6 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFQ93261.1 - 0.032 13.8 0.2 0.055 13.0 0.2 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KFQ93261.1 - 0.038 13.7 0.2 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KFQ93261.1 - 0.041 13.6 0.1 0.072 12.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 KFQ93261.1 - 0.049 12.8 1.9 0.5 9.5 0.2 2.3 2 1 1 3 3 3 0 G-protein alpha subunit NB-ARC PF00931.22 KFQ93261.1 - 0.057 12.6 0.1 0.1 11.8 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.26 KFQ93261.1 - 0.068 12.9 0.3 0.15 11.8 0.1 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KFQ93261.1 - 0.1 13.0 0.1 0.29 11.6 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Ploopntkinase3 PF18751.1 KFQ93261.1 - 0.13 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 DUF1542 PF07564.11 KFQ93261.1 - 0.15 12.2 0.1 0.31 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) MARVEL PF01284.23 KFQ93262.1 - 7.8e-20 71.4 33.8 6.3e-10 39.3 7.8 2.0 2 0 0 2 2 2 2 Membrane-associating domain TMPIT PF07851.13 KFQ93262.1 - 0.091 12.0 1.3 0.22 10.8 1.3 1.6 1 0 0 1 1 1 0 TMPIT-like protein IP_trans PF02121.18 KFQ93263.1 - 5.1e-47 160.5 0.0 5.4e-44 150.6 0.0 2.0 2 0 0 2 2 2 2 Phosphatidylinositol transfer protein TPR_8 PF13181.6 KFQ93265.1 - 5.1e-14 51.2 14.7 0.012 15.8 0.2 7.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ93265.1 - 4e-12 45.3 19.2 0.0043 17.1 0.0 7.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ93265.1 - 9.7e-12 44.2 18.2 0.0075 16.0 0.0 7.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ93265.1 - 3e-11 43.1 8.2 0.055 14.3 0.2 6.4 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ93265.1 - 4.1e-06 27.0 15.4 0.00027 21.2 0.2 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ93265.1 - 7.7e-06 26.5 3.7 0.052 14.2 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ93265.1 - 0.0033 17.6 19.4 0.007 16.6 2.5 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KFQ93265.1 - 0.0037 17.2 7.5 17 5.7 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFQ93265.1 - 0.0037 17.4 3.0 3.5 7.8 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ93265.1 - 0.0065 17.0 11.7 0.12 12.9 0.1 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ93265.1 - 0.018 15.4 4.8 79 4.0 0.2 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFQ93265.1 - 0.11 13.2 6.5 39 5.2 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ93265.1 - 0.76 9.5 9.0 4.8 6.9 0.0 4.5 4 1 2 6 6 6 0 TPR repeat WD40 PF00400.32 KFQ93266.1 - 5e-50 166.4 54.8 4.2e-07 30.6 0.4 20.6 21 0 0 21 21 21 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ93266.1 - 2.5e-23 82.2 0.0 0.0078 16.5 0.1 11.3 7 4 6 13 13 11 5 Anaphase-promoting complex subunit 4 WD40 domain DUF667 PF05018.13 KFQ93266.1 - 4e-17 62.5 0.0 8.8e-13 48.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF667) eIF2A PF08662.11 KFQ93266.1 - 6.7e-05 22.8 0.0 11 5.8 0.0 5.9 6 2 1 7 7 7 1 Eukaryotic translation initiation factor eIF2A HELP PF03451.14 KFQ93266.1 - 0.00034 20.4 0.0 0.65 9.9 0.0 2.5 2 0 0 2 2 2 2 HELP motif Ge1_WD40 PF16529.5 KFQ93266.1 - 0.00047 19.2 4.5 4.6 6.1 0.1 5.5 5 1 1 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 KFQ93266.1 - 0.01 15.9 0.0 5.4 7.1 0.0 3.9 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 KFQ93266.1 - 0.012 14.3 4.8 0.17 10.5 0.0 4.4 5 0 0 5 5 5 0 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 KFQ93266.1 - 0.021 14.1 0.0 4.4 6.5 0.0 3.2 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40_like PF17005.5 KFQ93266.1 - 0.046 13.0 0.0 24 4.1 0.0 3.8 3 1 1 4 4 4 0 WD40-like domain Me-amine-dh_H PF06433.11 KFQ93266.1 - 0.098 11.5 0.0 0.96 8.2 0.0 2.6 3 0 0 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) Coatomer_WDAD PF04053.14 KFQ93266.1 - 0.11 11.5 0.0 0.33 9.9 0.0 1.8 1 0 0 1 1 1 0 Coatomer WD associated region PQQ_2 PF13360.6 KFQ93266.1 - 0.18 11.3 0.9 5.9 6.4 0.0 3.7 3 1 1 4 4 4 0 PQQ-like domain EF_assoc_2 PF08356.12 KFQ93267.1 - 1.5e-36 124.2 0.0 3.8e-36 122.9 0.0 1.7 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 KFQ93267.1 - 1.1e-24 85.9 0.5 8.4e-24 83.0 0.0 2.4 2 1 0 2 2 2 1 EF hand associated Ras PF00071.22 KFQ93267.1 - 2e-22 79.5 0.0 1.5e-15 57.1 0.0 2.3 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KFQ93267.1 - 4.1e-09 36.7 0.0 3.8e-05 23.9 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_7 PF13499.6 KFQ93267.1 - 1.1e-06 29.0 0.0 0.0035 17.8 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFQ93267.1 - 1.5e-06 27.7 0.8 0.0002 21.0 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KFQ93267.1 - 2.5e-06 26.6 0.5 0.0018 17.7 0.1 2.5 2 0 0 2 2 2 2 EF hand MMR_HSR1 PF01926.23 KFQ93267.1 - 0.00033 20.7 0.0 0.48 10.5 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 KFQ93267.1 - 0.00076 19.6 0.0 0.32 11.1 0.0 2.3 2 0 0 2 2 2 2 Dynamin family EF-hand_5 PF13202.6 KFQ93267.1 - 0.00098 18.5 0.1 0.0023 17.4 0.1 1.6 1 0 0 1 1 1 1 EF hand RsgA_GTPase PF03193.16 KFQ93267.1 - 0.028 14.3 0.0 52 3.7 0.0 4.5 4 1 1 5 5 5 0 RsgA GTPase Arf PF00025.21 KFQ93267.1 - 0.05 13.0 0.0 0.49 9.8 0.0 2.5 3 1 0 3 3 3 0 ADP-ribosylation factor family SPARC_Ca_bdg PF10591.9 KFQ93267.1 - 0.051 13.9 0.1 4.6 7.6 0.0 2.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region ABC_tran PF00005.27 KFQ93267.1 - 0.07 13.6 0.0 6.3 7.3 0.0 2.4 2 0 0 2 2 2 0 ABC transporter EF-hand_10 PF14788.6 KFQ93267.1 - 0.071 13.0 1.3 2.2 8.2 0.1 2.5 2 0 0 2 2 2 0 EF hand AAA_14 PF13173.6 KFQ93267.1 - 0.1 12.6 0.0 8 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain EF-hand_8 PF13833.6 KFQ93267.1 - 0.13 12.1 0.1 22 5.0 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain pair FtsK_SpoIIIE PF01580.18 KFQ93267.1 - 0.19 11.1 0.0 0.49 9.7 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Rhomboid PF01694.22 KFQ93268.1 - 8.4e-22 77.8 5.1 6.6e-21 74.9 5.1 2.2 1 1 0 1 1 1 1 Rhomboid family LRR_6 PF13516.6 KFQ93269.1 - 8.7e-12 44.1 11.0 0.067 13.3 0.0 8.6 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.7 KFQ93269.1 - 1.1e-08 35.2 2.4 0.059 13.8 0.1 4.9 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFQ93269.1 - 0.00016 21.4 3.9 1.3 8.8 0.5 4.6 4 1 0 4 4 4 2 Leucine rich repeat F-box-like PF12937.7 KFQ93269.1 - 0.0043 16.9 1.0 0.014 15.2 1.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFQ93269.1 - 0.0069 16.2 2.3 0.034 14.0 0.1 2.7 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 KFQ93269.1 - 0.0082 16.5 14.4 0.46 11.2 0.0 6.5 7 1 0 7 7 7 2 Leucine Rich Repeat Methyltransf_23 PF13489.6 KFQ93270.1 - 0.031 14.1 0.0 0.033 14.0 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KFQ93270.1 - 0.089 12.6 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain OmpH PF03938.14 KFQ93271.1 - 0.0062 16.9 31.8 0.035 14.5 12.8 3.1 3 0 0 3 3 3 2 Outer membrane protein (OmpH-like) DUF1664 PF07889.12 KFQ93271.1 - 0.022 14.8 3.6 0.022 14.8 3.6 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4763 PF15960.5 KFQ93271.1 - 0.057 12.7 18.7 0.059 12.7 0.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4763) Ribosomal_S20p PF01649.18 KFQ93271.1 - 0.063 13.9 7.1 2.2 9.0 0.4 3.8 3 1 1 4 4 4 0 Ribosomal protein S20 BLOC1S3 PF15753.5 KFQ93271.1 - 0.17 12.0 11.1 0.21 11.7 7.8 2.6 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Spc7 PF08317.11 KFQ93271.1 - 1.2 7.9 27.2 0.021 13.7 8.8 2.7 2 1 0 2 2 2 0 Spc7 kinetochore protein FapA PF03961.13 KFQ93271.1 - 3.3 6.2 15.1 0.54 8.8 4.4 2.4 2 1 0 2 2 2 0 Flagellar Assembly Protein A DLP_helical PF18709.1 KFQ93271.1 - 3.6 6.7 15.1 0.053 12.7 4.7 2.7 2 2 0 2 2 2 0 Dynamin-like helical domain Lectin_N PF03954.14 KFQ93271.1 - 4.3 7.1 13.4 0.27 11.0 3.2 2.9 3 1 0 3 3 3 0 Hepatic lectin, N-terminal domain DUF883 PF05957.13 KFQ93271.1 - 7.4 7.2 21.7 4.1 8.1 2.6 4.2 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) ParA PF10609.9 KFQ93272.1 - 4.1e-99 331.0 0.0 4.7e-99 330.8 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KFQ93272.1 - 1.8e-12 47.4 0.0 9.6e-12 45.1 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KFQ93272.1 - 4.5e-08 33.2 0.2 3.6e-07 30.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 KFQ93272.1 - 5.8e-08 32.3 0.0 2.1e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 KFQ93272.1 - 9.1e-07 28.3 0.6 6.3e-06 25.6 0.0 2.3 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_26 PF13500.6 KFQ93272.1 - 2.5e-06 27.4 0.0 2.5e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 KFQ93272.1 - 5.3e-05 22.3 0.1 8.3e-05 21.7 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Fer4_NifH PF00142.18 KFQ93272.1 - 0.00024 20.7 0.0 0.0042 16.6 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 KFQ93272.1 - 0.0011 18.5 0.0 0.0028 17.2 0.0 1.6 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ APS_kinase PF01583.20 KFQ93272.1 - 0.0083 16.0 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_25 PF13481.6 KFQ93272.1 - 0.0085 15.7 0.1 0.019 14.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFQ93272.1 - 0.011 15.1 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.22 KFQ93272.1 - 0.029 14.0 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain KTI12 PF08433.10 KFQ93272.1 - 0.031 13.7 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CLP1_P PF16575.5 KFQ93272.1 - 0.057 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NB-ARC PF00931.22 KFQ93272.1 - 0.09 11.9 0.2 0.13 11.4 0.2 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 KFQ93272.1 - 0.11 13.0 0.0 0.17 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFQ93272.1 - 0.13 12.7 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain zf-C4_ClpX PF06689.13 KFQ93272.1 - 0.2 11.6 1.4 0.41 10.6 1.4 1.5 1 0 0 1 1 1 0 ClpX C4-type zinc finger NTPase_1 PF03266.15 KFQ93272.1 - 0.25 11.3 0.3 0.49 10.3 0.3 1.4 1 0 0 1 1 1 0 NTPase RsgA_GTPase PF03193.16 KFQ93272.1 - 0.33 10.8 1.2 0.64 9.9 0.6 1.7 2 0 0 2 2 2 0 RsgA GTPase SPRY PF00622.28 KFQ93273.1 - 4e-12 46.3 1.3 6.5e-12 45.6 0.6 1.7 2 0 0 2 2 2 1 SPRY domain PDZ PF00595.24 KFQ93274.1 - 6.4e-12 45.7 0.0 1.7e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFQ93274.1 - 0.0052 16.6 0.0 0.022 14.6 0.0 2.1 2 0 0 2 2 2 1 PDZ domain DUF1192 PF06698.11 KFQ93274.1 - 0.0061 16.6 5.8 0.12 12.5 1.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) DUF812 PF05667.11 KFQ93274.1 - 0.12 11.2 15.0 0.16 10.8 15.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Laminin_II PF06009.12 KFQ93274.1 - 0.14 12.2 9.3 0.27 11.3 9.3 1.5 1 0 0 1 1 1 0 Laminin Domain II DUF2730 PF10805.8 KFQ93274.1 - 0.16 12.1 5.3 0.42 10.7 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) PKcGMP_CC PF16808.5 KFQ93274.1 - 0.22 11.4 5.3 3.3 7.6 0.4 3.1 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TPR_MLP1_2 PF07926.12 KFQ93274.1 - 0.28 11.3 23.0 0.026 14.6 9.8 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FAP206 PF12018.8 KFQ93274.1 - 0.38 10.2 8.0 0.18 11.3 2.7 2.1 1 1 1 2 2 2 0 Domain of unknown function Med9 PF07544.13 KFQ93274.1 - 0.53 10.4 8.7 0.35 11.0 3.2 2.6 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 CCDC74_C PF14917.6 KFQ93274.1 - 0.77 10.3 6.6 1.2 9.7 5.8 1.8 1 1 0 1 1 1 0 Coiled coil protein 74, C terminal DUF5082 PF16888.5 KFQ93274.1 - 1.3 9.3 9.1 2.9 8.2 9.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) FUSC PF04632.12 KFQ93274.1 - 4.4 5.7 10.7 5.8 5.3 10.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family GIT_CC PF16559.5 KFQ93274.1 - 5.1 7.0 13.1 27 4.7 6.1 3.5 2 2 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4763 PF15960.5 KFQ93274.1 - 8.6 5.6 20.0 0.033 13.5 7.4 2.5 2 1 0 3 3 3 0 Domain of unknown function (DUF4763) PRELI PF04707.14 KFQ93275.1 - 1.3e-44 151.8 0.4 2e-44 151.2 0.4 1.3 1 0 0 1 1 1 1 PRELI-like family CRAL_TRIO PF00650.20 KFQ93275.1 - 6.8e-43 146.1 0.0 1.9e-42 144.7 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFQ93275.1 - 2e-07 31.1 0.1 5.2e-07 29.8 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain NAGPA PF09992.9 KFQ93276.1 - 4.8e-39 134.3 0.2 6.1e-39 133.9 0.2 1.1 1 0 0 1 1 1 1 Phosphodiester glycosidase Glycos_transf_1 PF00534.20 KFQ93277.1 - 1.2e-08 34.7 0.0 1.6e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFQ93277.1 - 4.6e-06 27.1 0.0 6.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFQ93277.1 - 5.1e-05 23.3 0.1 7.6e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KFQ93277.1 - 0.00014 22.4 0.0 0.00021 21.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KFQ93277.1 - 0.023 15.1 0.0 0.047 14.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Methyltransf_16 PF10294.9 KFQ93278.1 - 3e-17 62.9 0.0 3.5e-08 33.4 0.0 2.1 1 1 1 2 2 2 2 Lysine methyltransferase Met_10 PF02475.16 KFQ93278.1 - 0.0072 16.1 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 KFQ93278.1 - 0.013 16.1 0.0 0.025 15.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KFQ93278.1 - 0.022 14.3 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 KFQ93278.1 - 0.025 15.3 0.0 0.065 14.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Peptidase_C2 PF00648.21 KFQ93279.1 - 1.6e-81 273.6 0.0 2.3e-81 273.1 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease zf-RanBP PF00641.18 KFQ93279.1 - 4.3e-24 83.5 52.1 6.7e-08 31.7 1.9 6.8 6 0 0 6 6 6 5 Zn-finger in Ran binding protein and others DZR PF12773.7 KFQ93279.1 - 0.43 10.7 59.5 0.082 12.9 8.4 5.5 6 0 0 6 6 6 0 Double zinc ribbon Gpi1 PF05024.15 KFQ93281.1 - 6.4e-65 218.7 10.1 6.4e-65 218.7 10.1 2.0 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Ras PF00071.22 KFQ93282.1 - 1e-33 116.3 0.0 1.3e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ93282.1 - 5.8e-14 52.3 0.0 8.6e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SOCS_box PF07525.16 KFQ93282.1 - 1.4e-07 31.7 0.4 2.7e-07 30.8 0.4 1.5 1 0 0 1 1 1 1 SOCS box Arf PF00025.21 KFQ93282.1 - 0.0096 15.4 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Kunitz_BPTI PF00014.23 KFQ93283.1 - 3.9e-33 113.5 22.8 5.1e-19 68.2 4.8 3.2 3 0 0 3 3 3 2 Kunitz/Bovine pancreatic trypsin inhibitor domain I-set PF07679.16 KFQ93283.1 - 6.4e-16 58.2 0.0 1.1e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ93283.1 - 7.6e-15 55.3 0.0 1.6e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFQ93283.1 - 2e-10 40.9 0.0 4.4e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFQ93283.1 - 9.1e-10 38.6 0.0 2e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain NTR PF01759.21 KFQ93283.1 - 1.6e-07 31.0 0.0 3.2e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 UNC-6/NTR/C345C module V-set PF07686.17 KFQ93283.1 - 5.2e-05 23.4 0.0 0.0005 20.2 0.0 2.3 1 1 0 1 1 1 1 Immunoglobulin V-set domain Kazal_2 PF07648.15 KFQ93283.1 - 0.0039 17.3 6.7 0.0039 17.3 6.7 3.1 3 1 0 3 3 3 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFQ93283.1 - 0.052 13.6 9.0 0.076 13.0 7.2 2.3 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain FAM195 PF14799.6 KFQ93284.1 - 2.7e-31 108.0 0.1 3.1e-31 107.7 0.1 1.0 1 0 0 1 1 1 1 FAM195 family LAP2alpha PF11560.8 KFQ93284.1 - 0.1 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 2 alpha ABC2_membrane_3 PF12698.7 KFQ93285.1 - 6.3e-65 219.6 35.8 3.9e-35 121.6 22.7 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 KFQ93285.1 - 1.8e-49 167.8 0.0 2e-24 86.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KFQ93285.1 - 5e-19 69.2 0.1 9.3e-06 25.7 0.0 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFQ93285.1 - 0.00013 22.0 0.7 0.0031 17.5 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase SbcCD_C PF13558.6 KFQ93285.1 - 0.00054 20.1 0.0 0.016 15.5 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KFQ93285.1 - 0.00065 20.2 4.1 0.038 14.5 0.1 3.1 3 0 0 3 3 3 1 AAA domain DUF4162 PF13732.6 KFQ93285.1 - 0.0031 18.2 0.0 0.29 11.9 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_22 PF13401.6 KFQ93285.1 - 0.012 15.9 1.2 1.3 9.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KFQ93285.1 - 0.012 15.3 0.2 0.67 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KFQ93285.1 - 0.018 15.1 0.2 1.2 9.2 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_15 PF13175.6 KFQ93285.1 - 0.025 14.3 0.0 0.27 10.9 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain SMC_N PF02463.19 KFQ93285.1 - 0.026 13.9 0.0 13 5.1 0.0 3.2 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFQ93285.1 - 0.034 13.9 2.3 0.33 10.7 0.2 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Arf PF00025.21 KFQ93285.1 - 0.063 12.7 0.5 12 5.3 0.1 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_24 PF13479.6 KFQ93285.1 - 0.085 12.6 1.1 25 4.5 0.1 3.1 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 KFQ93285.1 - 0.11 12.1 4.8 1 9.0 0.4 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KFQ93285.1 - 0.11 12.8 0.1 1.7 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 KFQ93285.1 - 0.18 11.7 0.0 2.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain cobW PF02492.19 KFQ93285.1 - 0.8 9.3 2.9 9.9 5.7 0.1 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pkinase PF00069.25 KFQ93286.1 - 1.9e-08 34.0 0.0 2.2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KFQ93286.1 - 5.7e-06 25.4 0.0 7.5e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KFQ93286.1 - 3.6e-05 23.2 0.0 4.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Cyclin_N PF00134.23 KFQ93287.1 - 8e-28 96.7 3.5 3.3e-27 94.7 0.4 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFQ93287.1 - 2.1e-17 63.3 0.3 5.4e-17 62.0 0.3 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain F-box PF00646.33 KFQ93287.1 - 1.7e-05 24.5 0.1 5.2e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFQ93287.1 - 5.4e-05 23.0 0.1 0.00021 21.1 0.1 2.1 1 0 0 1 1 1 1 F-box-like Sel1 PF08238.12 KFQ93287.1 - 0.2 12.4 0.9 40 5.1 0.0 3.7 3 0 0 3 3 3 0 Sel1 repeat DUF4693 PF15764.5 KFQ93288.1 - 2.4e-97 326.0 5.7 3e-97 325.7 5.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4693) K_channel_TID PF07941.11 KFQ93288.1 - 0.071 13.6 0.7 0.15 12.5 0.7 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Sulfotransfer_1 PF00685.27 KFQ93289.1 - 6.7e-26 91.4 0.4 9.1e-26 90.9 0.4 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFQ93289.1 - 2.1e-17 64.2 1.0 5.3e-10 40.0 0.0 3.1 2 1 1 3 3 3 2 Sulfotransferase family TM231 PF10149.9 KFQ93290.1 - 4.8e-107 357.8 0.5 5.4e-107 357.6 0.5 1.0 1 0 0 1 1 1 1 Transmembrane protein 231 Atg8 PF02991.16 KFQ93291.1 - 7.5e-41 138.5 0.1 8.3e-41 138.4 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KFQ93291.1 - 2.2e-06 28.0 0.0 2.5e-06 27.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 CTXphi_pIII-N1 PF16710.5 KFQ93291.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.3 1 1 0 1 1 1 0 N-terminal N1 domain of Vibrio phage CTXphi pIII A_deamin PF02137.18 KFQ93292.1 - 7e-122 407.0 0.2 2.2e-121 405.3 0.2 1.7 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain tRNA-synt_2 PF00152.20 KFQ93293.1 - 1.3e-74 251.1 0.2 1.7e-74 250.7 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFQ93293.1 - 1.8e-16 59.9 0.0 7.4e-16 57.9 0.0 2.1 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KFQ93293.1 - 9.9e-07 28.5 0.1 0.0065 16.0 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) Rap1_C PF11626.8 KFQ93294.1 - 4.6e-11 42.7 0.1 6.5e-11 42.2 0.1 1.2 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Sulfotransfer_1 PF00685.27 KFQ93295.1 - 4.8e-28 98.4 0.1 6.8e-28 97.9 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFQ93295.1 - 4.3e-17 63.2 1.5 8.3e-10 39.4 0.0 3.0 2 1 1 3 3 3 3 Sulfotransferase family Aminotran_1_2 PF00155.21 KFQ93296.1 - 1.5e-73 248.1 0.0 1.7e-73 247.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II TAT_ubiq PF07706.12 KFQ93296.1 - 3.5e-18 65.5 0.4 5.7e-18 64.8 0.4 1.3 1 0 0 1 1 1 1 Aminotransferase ubiquitination site Aminotran_5 PF00266.19 KFQ93296.1 - 8.9e-07 28.2 0.0 1.3e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFQ93296.1 - 3.2e-05 23.4 0.0 4.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KFQ93296.1 - 5.4e-05 22.7 0.0 8.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KFQ93296.1 - 0.0033 16.0 0.0 0.005 15.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.7 KFQ93296.1 - 0.13 11.0 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase MARVEL PF01284.23 KFQ93297.1 - 2.2e-05 24.5 3.7 2.8e-05 24.2 3.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain Phage_holin_3_6 PF07332.11 KFQ93297.1 - 2.2 8.3 8.8 2e+02 2.0 8.5 2.1 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF997 PF06196.12 KFQ93297.1 - 9.8 6.3 9.0 3.6 7.6 5.5 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF997) Ferlin_C PF16165.5 KFQ93298.1 - 0.27 11.2 1.4 0.4 10.6 1.4 1.2 1 0 0 1 1 1 0 Ferlin C-terminus LRR_8 PF13855.6 KFQ93299.1 - 1.3e-40 137.0 64.4 3.8e-09 36.2 4.4 9.4 7 2 2 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 KFQ93299.1 - 7.1e-28 96.2 70.2 4.7e-07 30.0 3.9 12.3 3 2 10 15 15 15 14 Leucine Rich repeats (2 copies) PP2C PF00481.21 KFQ93299.1 - 1e-25 90.9 0.0 1.6e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_1 PF00560.33 KFQ93299.1 - 0.00025 21.2 65.7 3.7 8.5 0.3 16.5 16 2 0 16 16 16 3 Leucine Rich Repeat PH PF00169.29 KFQ93299.1 - 0.00046 20.7 0.0 0.00099 19.6 0.0 1.5 1 0 0 1 1 1 1 PH domain LRR_6 PF13516.6 KFQ93299.1 - 0.017 15.2 60.0 1.8 8.8 0.2 15.1 15 2 1 16 16 16 0 Leucine Rich repeat Adaptin_N PF01602.20 KFQ93300.1 - 4.5e-154 513.9 8.8 5.4e-154 513.6 8.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KFQ93300.1 - 1.2e-35 122.1 4.7 2.2e-35 121.3 4.7 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KFQ93300.1 - 7.5e-13 48.8 3.9 1.9e-09 37.7 0.1 3.5 2 2 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 RVT_1 PF00078.27 KFQ93301.1 - 0.0023 17.5 0.0 0.004 16.7 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) ig PF00047.25 KFQ93301.1 - 0.074 13.2 0.0 0.088 13.0 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain AXH PF08517.12 KFQ93302.1 - 4e-41 140.2 0.0 7.3e-41 139.4 0.0 1.4 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) Pap_E4 PF02711.14 KFQ93302.1 - 1.8 9.6 8.7 1.1 10.2 3.9 2.7 2 0 0 2 2 2 0 E4 protein zf-C2H2_4 PF13894.6 KFQ93303.1 - 1.2e-07 31.9 6.5 0.0022 18.7 0.0 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KFQ93303.1 - 6.1e-07 29.6 2.7 0.99 9.9 0.2 3.5 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFQ93303.1 - 9.9e-05 22.6 5.0 0.00065 19.9 5.0 2.3 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KFQ93303.1 - 0.00023 21.5 11.6 0.0022 18.4 0.0 3.7 4 0 0 4 4 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ93303.1 - 0.0013 19.0 0.4 0.88 10.1 0.0 3.9 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_9 PF16293.5 KFQ93303.1 - 0.002 17.9 1.2 2.8 7.9 0.1 3.2 1 1 1 2 2 2 2 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 KFQ93303.1 - 0.0042 16.8 0.2 0.0042 16.8 0.2 3.0 3 0 0 3 3 3 2 zinc-finger C2H2-type DZR PF12773.7 KFQ93303.1 - 0.013 15.5 2.9 0.083 12.9 2.1 2.6 2 1 1 3 3 3 0 Double zinc ribbon Rad50_zn_hook PF04423.14 KFQ93303.1 - 0.014 15.2 2.4 0.3 10.9 0.0 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C2H2_jaz PF12171.8 KFQ93303.1 - 0.025 14.8 0.1 15 6.0 0.4 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFQ93303.1 - 0.056 13.5 6.2 0.84 9.7 0.0 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger PhnA_Zn_Ribbon PF08274.12 KFQ93303.1 - 0.093 12.7 9.8 11 6.1 0.1 4.0 3 1 0 3 3 3 0 PhnA Zinc-Ribbon Prok-RING_4 PF14447.6 KFQ93303.1 - 0.43 10.5 7.2 23 4.9 0.6 3.9 4 0 0 4 4 4 0 Prokaryotic RING finger family 4 Peptidase_S46 PF10459.9 KFQ93303.1 - 2.1 6.9 9.5 3.2 6.3 9.5 1.2 1 0 0 1 1 1 0 Peptidase S46 Ist1 PF03398.14 KFQ93305.1 - 6.4e-63 211.6 4.2 7.7e-63 211.3 4.2 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DHO_dh PF01180.21 KFQ93306.1 - 5.2e-111 370.6 0.0 6.2e-111 370.3 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 KFQ93306.1 - 0.002 17.2 0.5 0.013 14.5 0.6 2.2 2 1 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 KFQ93306.1 - 0.011 15.1 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase HA2 PF04408.23 KFQ93307.1 - 7.7e-20 71.2 0.0 7.7e-20 71.2 0.0 4.7 4 1 0 4 4 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFQ93307.1 - 2.7e-16 59.7 0.0 6.2e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFQ93307.1 - 6e-14 52.3 0.0 1.4e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFQ93307.1 - 3.7e-07 30.1 0.0 1e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFQ93307.1 - 2.2e-05 24.8 0.0 6.4e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFQ93307.1 - 0.00057 19.7 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFQ93307.1 - 0.0012 19.2 0.0 0.003 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KFQ93307.1 - 0.0022 17.1 0.0 0.0043 16.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 KFQ93307.1 - 0.0028 17.6 0.0 0.0062 16.5 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain DUF2075 PF09848.9 KFQ93307.1 - 0.0041 16.4 1.8 0.01 15.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KFQ93307.1 - 0.014 14.9 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.22 KFQ93307.1 - 0.029 14.0 0.1 0.072 12.7 0.1 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KFQ93307.1 - 0.063 13.7 0.0 0.21 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KFQ93307.1 - 0.071 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KFQ93307.1 - 0.17 12.0 0.0 0.17 12.0 0.0 3.3 3 0 0 3 3 1 0 AAA domain BRE1 PF08647.11 KFQ93308.1 - 0.002 18.1 5.9 0.002 18.1 5.9 2.7 2 1 0 2 2 2 1 BRE1 E3 ubiquitin ligase BBS2_C PF14782.6 KFQ93308.1 - 0.0066 15.3 5.0 0.0066 15.3 5.0 1.5 1 1 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal Tropomyosin PF00261.20 KFQ93308.1 - 0.0074 15.7 12.6 0.091 12.1 1.4 2.1 2 0 0 2 2 2 2 Tropomyosin Imm27 PF15590.6 KFQ93308.1 - 0.012 15.4 0.5 0.59 9.9 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 27 Spc7 PF08317.11 KFQ93308.1 - 0.052 12.4 22.0 0.38 9.6 4.2 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Rsd_AlgQ PF04353.13 KFQ93308.1 - 0.12 12.3 8.6 0.28 11.1 1.5 2.2 2 0 0 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ DUF4795 PF16043.5 KFQ93308.1 - 0.2 11.2 13.1 0.25 10.9 13.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) HrpB7 PF09486.10 KFQ93308.1 - 0.46 10.9 25.9 3.9 7.9 22.9 2.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) GAS PF13851.6 KFQ93308.1 - 0.63 9.4 18.0 0.42 9.9 4.5 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 KFQ93308.1 - 2.6 7.3 15.5 3.3 7.0 15.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Uso1_p115_C PF04871.13 KFQ93308.1 - 5.1 7.5 23.3 2.1 8.7 4.2 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Allexi_40kDa PF05549.11 KFQ93308.1 - 5.6 6.4 10.6 0.56 9.7 2.7 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein YabA PF06156.13 KFQ93308.1 - 9 7.0 13.2 2.3 8.9 3.3 2.1 2 0 0 2 2 2 0 Initiation control protein YabA CLZ PF16526.5 KFQ93308.1 - 9.2 6.7 17.4 9.1 6.7 2.2 2.5 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Homeodomain PF00046.29 KFQ93309.1 - 1.1e-66 220.6 19.5 1.7e-17 63.0 0.7 5.0 4 0 0 4 4 4 4 Homeodomain zf-C2H2_4 PF13894.6 KFQ93309.1 - 3.3e-14 52.4 138.1 0.095 13.6 3.7 23.5 24 0 0 24 24 23 12 C2H2-type zinc finger zf-C2H2 PF00096.26 KFQ93309.1 - 1.9e-13 50.1 155.6 0.0045 17.4 0.4 22.4 24 0 0 24 24 23 12 Zinc finger, C2H2 type Homeobox_KN PF05920.11 KFQ93309.1 - 6.3e-11 42.0 2.2 0.033 14.1 0.1 4.8 4 0 0 4 4 4 3 Homeobox KN domain zf-met PF12874.7 KFQ93309.1 - 9.2e-08 32.2 108.3 0.00036 20.8 0.9 17.2 18 0 0 18 18 17 8 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFQ93309.1 - 1.1e-05 25.7 5.8 1.1e-05 25.7 5.8 11.6 13 1 1 14 14 14 4 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 KFQ93309.1 - 0.00048 19.8 0.8 0.00048 19.8 0.8 11.5 11 0 0 11 11 11 4 C2H2-type zinc-finger domain MerR_1 PF13411.6 KFQ93309.1 - 0.016 15.3 0.2 0.25 11.4 0.0 3.2 4 0 0 4 4 4 0 MerR HTH family regulatory protein GLTT PF01744.20 KFQ93309.1 - 0.069 12.9 1.0 0.15 11.9 1.0 1.5 1 0 0 1 1 1 0 GLTT repeat (6 copies) zf-C2H2_2 PF12756.7 KFQ93309.1 - 1.3 9.4 136.4 0.58 10.5 2.0 20.2 17 6 4 21 21 20 0 C2H2 type zinc-finger (2 copies) zf_Hakai PF18408.1 KFQ93309.1 - 6.1 6.6 6.1 37 4.1 0.5 3.9 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain zf_C2H2_10 PF18414.1 KFQ93309.1 - 7.7 6.2 11.0 4.1 7.0 0.0 4.7 4 0 0 4 4 4 0 C2H2 type zinc-finger MitMem_reg PF13012.6 KFQ93310.1 - 3.2e-36 124.2 0.5 5.3e-36 123.4 0.5 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KFQ93310.1 - 1.2e-25 89.8 1.8 1.7e-25 89.3 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Coilin_N PF15862.5 KFQ93310.1 - 0.003 17.4 8.6 0.0051 16.6 8.6 1.3 1 0 0 1 1 1 1 Coilin N-terminus Connexin PF00029.19 KFQ93310.1 - 0.027 14.2 5.6 0.048 13.4 5.6 1.3 1 0 0 1 1 1 0 Connexin HECT PF00632.25 KFQ93311.1 - 1.8e-97 326.6 0.2 2.7e-97 326.0 0.2 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KFQ93311.1 - 1.1e-47 159.7 33.8 1.6e-13 50.5 4.8 4.6 4 0 0 4 4 4 4 WW domain NOB1_Zn_bind PF08772.11 KFQ93312.1 - 1.7e-33 114.6 0.2 3e-33 113.8 0.2 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 KFQ93312.1 - 3e-24 85.3 0.0 6.2e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 PIN domain of ribonuclease WRNPLPNID PF15017.6 KFQ93312.1 - 4.3e-19 69.2 9.3 5.4e-19 68.8 7.6 2.0 2 0 0 2 2 2 1 Putative WW-binding domain and destruction box DUF4611 PF15387.6 KFQ93312.1 - 0.028 14.6 1.0 0.054 13.7 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RRP7 PF12923.7 KFQ93312.1 - 0.041 14.0 0.5 0.073 13.2 0.5 1.3 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Zn-ribbon_8 PF09723.10 KFQ93312.1 - 0.066 13.3 0.7 0.14 12.3 0.7 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Peptidase_C31 PF05410.13 KFQ93312.1 - 0.067 13.3 0.0 0.42 10.7 0.0 2.1 2 0 0 2 2 2 0 Porcine arterivirus-type cysteine proteinase alpha HypA PF01155.19 KFQ93312.1 - 0.088 12.8 0.5 0.16 12.0 0.5 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ribosomal_60s PF00428.19 KFQ93312.1 - 0.23 12.1 7.7 0.45 11.1 7.7 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein SPATIAL PF15256.6 KFQ93312.1 - 0.36 11.1 2.0 0.39 11.0 0.7 1.7 2 0 0 2 2 2 0 SPATIAL RHD_dimer PF16179.5 KFQ93313.1 - 3.8e-28 97.5 0.1 1.3e-27 95.9 0.1 2.0 1 0 0 1 1 1 1 Rel homology dimerisation domain RHD_DNA_bind PF00554.22 KFQ93313.1 - 4.5e-21 75.5 0.2 3.1e-20 72.8 0.2 2.5 1 1 0 1 1 1 1 Rel homology DNA-binding domain Cyt-b5 PF00173.28 KFQ93314.1 - 5.2e-12 45.7 0.0 7.7e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TERF2_RBM PF16772.5 KFQ93315.1 - 5.6e-24 83.3 0.8 1.1e-23 82.4 0.8 1.5 1 0 0 1 1 1 1 Telomeric repeat-binding factor 2 Rap1-binding motif TRF PF08558.10 KFQ93315.1 - 2.4e-22 79.7 1.5 4.7e-22 78.8 1.5 1.5 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 KFQ93315.1 - 3e-11 43.3 1.7 3e-11 43.3 1.7 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFQ93315.1 - 0.023 14.9 1.2 0.023 14.9 1.2 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain TIR_2 PF13676.6 KFQ93315.1 - 0.037 14.6 0.0 0.095 13.3 0.0 1.7 1 0 0 1 1 1 0 TIR domain Ribosomal_L36e PF01158.18 KFQ93315.1 - 0.098 12.9 3.2 0.3 11.3 3.2 1.8 1 0 0 1 1 1 0 Ribosomal protein L36e EMP24_GP25L PF01105.24 KFQ93316.1 - 1.3e-29 103.5 0.1 1.5e-29 103.3 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4304 PF14137.6 KFQ93316.1 - 0.014 15.5 0.5 0.025 14.7 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4304) UPF0113 PF03657.13 KFQ93317.1 - 5.3e-23 81.1 0.0 6.7e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 UPF0113 PUA domain UPF0113_N PF17833.1 KFQ93317.1 - 5.5e-08 33.3 0.0 1e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain PUA PF01472.20 KFQ93317.1 - 0.0065 16.4 0.0 0.0085 16.0 0.0 1.2 1 0 0 1 1 1 1 PUA domain PEPCK_GTP PF00821.18 KFQ93317.1 - 0.085 11.7 0.0 0.097 11.5 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain Dor1 PF04124.12 KFQ93318.1 - 4.4e-109 364.2 0.0 5.2e-109 364.0 0.0 1.0 1 0 0 1 1 1 1 Dor1-like family AAA PF00004.29 KFQ93320.1 - 1.7e-30 106.2 0.0 2e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KFQ93320.1 - 1.2e-06 28.0 0.0 1.7e-06 27.5 0.0 1.3 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KFQ93320.1 - 1.4e-06 28.7 0.1 0.00033 21.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFQ93320.1 - 1.6e-06 28.6 0.1 0.00075 19.9 0.0 2.1 1 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 KFQ93320.1 - 2e-06 27.6 0.0 2.8e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 KFQ93320.1 - 1.4e-05 25.1 0.0 1.9e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KFQ93320.1 - 1.9e-05 24.5 0.0 2.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KFQ93320.1 - 2.2e-05 24.5 0.0 5.7e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KFQ93320.1 - 2.6e-05 23.9 0.1 0.18 11.4 0.0 2.1 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.13 KFQ93320.1 - 0.00013 21.3 0.0 0.00015 21.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KFQ93320.1 - 0.00013 22.5 0.0 0.00023 21.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KFQ93320.1 - 0.00025 21.2 0.0 0.00039 20.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KFQ93320.1 - 0.00033 20.9 0.0 0.0013 18.9 0.0 1.7 1 1 1 2 2 2 1 AAA domain TniB PF05621.11 KFQ93320.1 - 0.0018 17.7 0.0 0.82 9.1 0.0 2.1 1 1 1 2 2 2 2 Bacterial TniB protein ATPase PF06745.13 KFQ93320.1 - 0.0023 17.3 0.1 1.1 8.5 0.0 2.1 1 1 1 2 2 2 2 KaiC NACHT PF05729.12 KFQ93320.1 - 0.0029 17.5 0.0 0.08 12.8 0.0 2.0 1 1 1 2 2 2 1 NACHT domain RNA_helicase PF00910.22 KFQ93320.1 - 0.0032 17.9 0.0 0.0053 17.1 0.0 1.5 1 1 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 KFQ93320.1 - 0.0034 17.1 0.0 0.0054 16.5 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KFQ93320.1 - 0.0049 16.4 0.0 0.011 15.3 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 KFQ93320.1 - 0.0066 15.9 0.2 0.014 14.8 0.0 1.7 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KFQ93320.1 - 0.0082 15.6 0.1 0.0095 15.4 0.1 1.3 1 1 0 1 1 1 1 PhoH-like protein Sigma54_activat PF00158.26 KFQ93320.1 - 0.0093 15.7 0.0 0.036 13.8 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain ATPase_2 PF01637.18 KFQ93320.1 - 0.0094 15.9 0.0 1.3 8.9 0.0 2.1 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_17 PF13207.6 KFQ93320.1 - 0.015 15.7 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KFQ93320.1 - 0.017 15.2 0.0 0.034 14.3 0.0 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 KFQ93320.1 - 0.026 14.2 0.0 0.047 13.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 KFQ93320.1 - 0.029 13.5 0.0 0.048 12.7 0.0 1.4 2 0 0 2 2 2 0 MCM P-loop domain AFG1_ATPase PF03969.16 KFQ93320.1 - 0.041 12.8 0.0 0.045 12.6 0.0 1.1 1 0 0 1 1 1 0 AFG1-like ATPase Zeta_toxin PF06414.12 KFQ93320.1 - 0.051 12.8 0.1 0.47 9.7 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin Guanylate_kin PF00625.21 KFQ93320.1 - 0.06 13.0 0.0 0.28 10.9 0.0 1.9 1 1 0 2 2 2 0 Guanylate kinase Parvo_NS1 PF01057.17 KFQ93320.1 - 0.061 12.4 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KFQ93320.1 - 0.065 13.5 0.0 0.12 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 KFQ93320.1 - 0.071 13.1 0.0 0.1 12.6 0.0 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit KAP_NTPase PF07693.14 KFQ93320.1 - 0.076 12.2 0.0 0.29 10.3 0.0 1.8 1 1 0 1 1 1 0 KAP family P-loop domain AAA_29 PF13555.6 KFQ93320.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KFQ93320.1 - 0.11 13.0 0.0 0.17 12.4 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.18 KFQ93320.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KFQ93320.1 - 0.15 11.3 0.0 0.19 10.9 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Torsin PF06309.11 KFQ93320.1 - 0.16 12.1 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Torsin MMR_HSR1 PF01926.23 KFQ93320.1 - 0.17 12.0 0.0 2 8.6 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase PH_17 PF18012.1 KFQ93321.1 - 2.7e-07 30.2 0.1 3.7e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 PH domain WD40 PF00400.32 KFQ93322.1 - 8.2 7.5 8.6 52 5.0 0.1 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat Ctf8 PF09696.10 KFQ93323.1 - 7.5e-08 32.8 0.4 2.4e-07 31.2 0.4 1.7 1 1 0 1 1 1 1 Ctf8 Glyco_tranf_2_3 PF13641.6 KFQ93324.1 - 4.9e-20 72.4 0.1 1.4e-15 57.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.15 KFQ93324.1 - 2e-18 66.3 0.7 7.2e-14 51.3 1.1 3.2 2 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KFQ93324.1 - 6.2e-10 39.3 16.1 2.6e-09 37.3 16.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KFQ93324.1 - 7.5e-10 38.9 0.0 0.00047 20.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KFQ93324.1 - 1.3e-05 24.7 0.0 2.9e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 DUF1294 PF06961.13 KFQ93324.1 - 0.14 12.5 1.5 0.25 11.6 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1294) Cadherin PF00028.17 KFQ93325.1 - 1.8e-71 236.6 2.2 8.9e-22 77.3 0.2 4.3 4 0 0 4 4 4 4 Cadherin domain Cadherin_C PF01049.17 KFQ93325.1 - 9.8e-12 45.4 0.0 1.9e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Cadherin cytoplasmic region Big_9 PF17963.1 KFQ93325.1 - 1.4e-09 38.6 18.9 0.00097 19.8 2.4 3.8 3 1 0 3 3 3 3 Bacterial Ig domain Cadherin_4 PF17803.1 KFQ93325.1 - 8.6e-08 32.7 19.7 0.0029 18.2 4.0 3.9 3 0 0 3 3 3 3 Bacterial cadherin-like domain Polyketide_cyc PF03364.20 KFQ93325.1 - 0.096 12.9 0.3 0.34 11.1 0.2 1.9 1 1 1 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport DUF4625 PF15418.6 KFQ93325.1 - 0.13 12.5 0.0 28 4.9 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4625) PKD PF00801.20 KFQ93325.1 - 0.25 11.2 1.4 12 5.8 0.1 3.2 3 0 0 3 3 3 0 PKD domain Transthyretin PF00576.21 KFQ93326.1 - 3e-37 127.7 0.0 3.3e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family DUF2271 PF10029.9 KFQ93326.1 - 0.02 14.5 0.1 0.33 10.6 0.0 2.0 1 1 1 2 2 2 0 Predicted periplasmic protein (DUF2271) GAS PF13851.6 KFQ93327.1 - 6.4e-81 270.5 32.4 6.4e-81 270.5 32.4 3.0 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding Metal_resist PF13801.6 KFQ93327.1 - 0.094 12.9 0.1 0.094 12.9 0.1 6.2 3 3 3 6 6 6 0 Heavy-metal resistance Baculo_PEP_C PF04513.12 KFQ93327.1 - 4.5 7.3 21.3 2.8 8.0 1.0 4.5 2 2 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3573 PF12097.8 KFQ93327.1 - 4.9 5.9 6.1 2.4 6.9 3.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) Dysbindin PF04440.16 KFQ93328.1 - 1.7e-36 125.6 0.0 2.1e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 Dysbindin (Dystrobrevin binding protein 1) Tubulin PF00091.25 KFQ93329.1 - 1.1e-52 179.2 0.0 1.7e-52 178.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFQ93329.1 - 6.9e-43 145.8 0.1 1.1e-42 145.1 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFQ93329.1 - 0.013 15.2 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 KFQ93329.1 - 0.036 13.2 0.0 0.07 12.3 0.0 1.4 1 0 0 1 1 1 0 Tubulin like Se-cys_synth_N PF12390.8 KFQ93330.1 - 0.14 12.4 0.7 2.4 8.4 0.1 2.6 2 0 0 2 2 2 0 Selenocysteine synthase N terminal 7tm_1 PF00001.21 KFQ93331.1 - 1.8e-34 119.2 37.0 4.2e-33 114.8 37.0 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFQ93331.1 - 1.1e-09 38.5 23.9 8.1e-09 35.6 21.2 2.7 1 1 1 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KFQ93331.1 - 9.6e-06 25.2 32.5 3.5e-05 23.3 32.5 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF809 PF05663.11 KFQ93331.1 - 0.44 10.7 5.4 0.46 10.6 3.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF809) Tcf25 PF04910.14 KFQ93333.1 - 1.7e-123 412.2 5.1 2.1e-123 411.9 5.1 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_12 PF13424.6 KFQ93333.1 - 0.09 13.1 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat SPT6_acidic PF14632.6 KFQ93333.1 - 0.11 13.1 11.8 0.03 14.9 8.5 1.9 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Adaptin_binding PF10199.9 KFQ93333.1 - 2 9.0 10.2 3.2 8.4 7.9 2.2 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 KIND PF16474.5 KFQ93334.1 - 1.4e-44 152.3 0.0 2.3e-44 151.6 0.0 1.3 1 0 0 1 1 1 1 Kinase non-catalytic C-lobe domain FYVE PF01363.21 KFQ93334.1 - 1.2 9.4 15.0 0.39 10.9 10.4 2.5 2 1 0 2 2 2 0 FYVE zinc finger Fanconi_A_N PF15865.5 KFQ93335.1 - 9.7e-128 426.4 0.9 2.5e-127 425.0 0.9 1.8 1 0 0 1 1 1 1 Fanconi anaemia group A protein N terminus Fanconi_A PF03511.14 KFQ93335.1 - 2.7e-24 84.8 2.8 3.6e-24 84.4 0.4 2.6 2 0 0 2 2 2 1 Fanconi anaemia group A protein zf-C2H2 PF00096.26 KFQ93336.1 - 1e-14 54.0 42.3 0.00014 22.2 2.2 6.5 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ93336.1 - 1.4e-13 50.4 40.9 0.0035 18.1 0.8 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFQ93336.1 - 1.4e-07 31.6 46.0 0.00033 21.0 1.1 7.2 7 1 0 7 7 7 4 Zinc-finger double domain zf-AD PF07776.15 KFQ93336.1 - 5.1e-05 23.4 8.9 0.0001 22.5 0.1 3.6 3 0 0 3 3 3 1 Zinc-finger associated domain (zf-AD) CpXC PF14353.6 KFQ93336.1 - 0.002 18.1 14.0 0.24 11.5 0.2 4.3 2 1 2 4 4 4 2 CpXC protein Zn-ribbon_8 PF09723.10 KFQ93336.1 - 0.0033 17.5 18.8 0.16 12.1 0.0 4.3 4 0 0 4 4 4 2 Zinc ribbon domain zf-C2H2_aberr PF17017.5 KFQ93336.1 - 0.0094 16.1 2.7 0.0094 16.1 2.7 2.3 1 1 2 3 3 3 1 Aberrant zinc-finger zf-C2H2_6 PF13912.6 KFQ93336.1 - 0.01 15.8 0.3 0.01 15.8 0.3 5.3 6 0 0 6 6 6 0 C2H2-type zinc finger RBR PF17208.3 KFQ93336.1 - 0.096 13.4 12.5 0.52 11.1 12.5 2.3 1 0 0 1 1 1 0 RNA binding Region zf_UBZ PF18439.1 KFQ93336.1 - 0.34 10.5 16.2 0.93 9.1 0.1 4.2 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger HypA PF01155.19 KFQ93336.1 - 1 9.4 9.5 7.6 6.6 1.6 3.3 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RbpA PF13397.6 KFQ93336.1 - 2.2 8.9 5.7 13 6.5 0.6 3.2 3 0 0 3 3 2 0 RNA polymerase-binding protein ADK_lid PF05191.14 KFQ93336.1 - 2.7 8.1 15.0 0.068 13.2 1.4 3.8 4 0 0 4 4 4 0 Adenylate kinase, active site lid zinc_ribbon_10 PF10058.9 KFQ93336.1 - 3.5 7.4 7.9 12 5.7 0.0 3.8 4 0 0 4 4 4 0 Predicted integral membrane zinc-ribbon metal-binding protein IBR PF01485.21 KFQ93336.1 - 4.5 7.6 23.4 2.7 8.3 0.5 4.6 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain DZR PF12773.7 KFQ93336.1 - 7.8 6.6 15.5 33 4.6 10.2 3.7 2 1 0 2 2 2 0 Double zinc ribbon Pkinase PF00069.25 KFQ93337.1 - 7.9e-66 222.1 0.0 9.2e-66 221.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ93337.1 - 6.9e-32 110.7 0.0 1.8e-31 109.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFQ93337.1 - 7e-08 31.8 0.0 1e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFQ93337.1 - 2.7e-07 30.2 0.2 2e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KFQ93337.1 - 0.0033 17.1 0.0 0.0054 16.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KFQ93337.1 - 0.0044 15.8 0.0 0.0065 15.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Herpes_IE1 PF07340.11 KFQ93337.1 - 0.023 13.6 0.1 0.033 13.1 0.1 1.1 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein APH PF01636.23 KFQ93337.1 - 0.052 13.5 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFQ93337.1 - 0.064 12.3 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 KFQ93337.1 - 0.091 12.1 0.0 0.2 11.0 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Snf7 PF03357.21 KFQ93338.1 - 6.7e-10 38.8 10.6 8.6e-10 38.5 10.6 1.1 1 0 0 1 1 1 1 Snf7 DMSP_lyase PF16867.5 KFQ93338.1 - 0.057 13.1 0.4 0.082 12.6 0.4 1.2 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Wbp11 PF09429.10 KFQ93338.1 - 0.12 12.8 0.4 0.43 11.0 0.1 2.0 1 1 1 2 2 2 0 WW domain binding protein 11 Fes1 PF08609.10 KFQ93338.1 - 0.38 11.7 4.9 0.28 12.1 1.0 2.2 1 1 1 2 2 2 0 Nucleotide exchange factor Fes1 Peptidase_M19 PF01244.21 KFQ93339.1 - 1.4e-46 159.1 1.5 1.5e-46 159.0 1.5 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) RTX_C PF08339.10 KFQ93339.1 - 0.16 12.1 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 RTX C-terminal domain Ribosomal_L13e PF01294.18 KFQ93340.1 - 1.4e-82 275.9 6.4 1.8e-82 275.6 6.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Peptidase_M41 PF01434.18 KFQ93341.1 - 1.1e-63 214.5 0.1 2e-63 213.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KFQ93341.1 - 6.6e-39 133.4 0.1 1.6e-38 132.1 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFQ93341.1 - 1.5e-14 53.5 0.1 5.6e-14 51.7 0.0 2.0 2 0 0 2 2 1 1 AAA+ lid domain FtsH_ext PF06480.15 KFQ93341.1 - 1.1e-07 32.1 0.0 3e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.6 KFQ93341.1 - 1.6e-06 28.6 0.0 3.6e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFQ93341.1 - 2.3e-06 27.6 0.4 3.3e-05 23.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFQ93341.1 - 0.00019 21.7 0.0 0.032 14.5 0.0 3.3 1 1 2 3 3 3 1 AAA domain AAA_2 PF07724.14 KFQ93341.1 - 0.00065 19.9 1.2 0.0014 18.8 0.0 2.2 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KFQ93341.1 - 0.00091 19.0 0.2 0.005 16.6 0.0 2.2 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFQ93341.1 - 0.0014 19.0 0.1 0.0053 17.1 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KFQ93341.1 - 0.0043 16.3 0.1 0.0079 15.4 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 KFQ93341.1 - 0.019 14.4 0.1 0.035 13.5 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KFQ93341.1 - 0.029 14.1 0.1 0.083 12.6 0.1 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF4491 PF14898.6 KFQ93341.1 - 0.036 14.5 0.0 0.087 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) AAA_28 PF13521.6 KFQ93341.1 - 0.089 13.0 0.4 0.26 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain PglZ PF08665.12 KFQ93341.1 - 0.1 12.7 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 PglZ domain NACHT PF05729.12 KFQ93341.1 - 0.11 12.4 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Peptidase_M50B PF13398.6 KFQ93341.1 - 0.14 11.8 1.0 0.32 10.6 0.1 1.9 2 0 0 2 2 2 0 Peptidase M50B-like CSTF2_hinge PF14327.6 KFQ93341.1 - 0.22 12.0 0.4 0.5 10.8 0.4 1.6 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 Ank_2 PF12796.7 KFQ93342.1 - 2.2e-18 66.6 0.2 2.9e-09 37.4 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFQ93342.1 - 8.4e-18 64.0 0.4 0.00017 21.8 0.1 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KFQ93342.1 - 1.8e-17 63.2 0.3 3.6e-08 33.5 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFQ93342.1 - 3.2e-14 53.1 0.2 3.7e-06 27.4 0.0 3.2 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ93342.1 - 8.5e-14 50.3 0.1 0.0007 19.9 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat YcbB PF08664.10 KFQ93343.1 - 0.02 15.0 1.8 0.02 15.0 1.8 2.8 3 0 0 3 3 3 0 YcbB domain AMP-binding PF00501.28 KFQ93344.1 - 8.1e-81 271.8 0.0 9.9e-81 271.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFQ93344.1 - 8.2e-16 58.8 0.1 1.9e-15 57.6 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ATR13 PF16829.5 KFQ93344.1 - 0.037 14.4 0.0 0.078 13.3 0.0 1.5 1 0 0 1 1 1 0 Avirulence protein ATR13, RxLR effector TAFH PF07531.14 KFQ93345.1 - 3.5e-35 120.0 1.1 5.9e-35 119.3 1.1 1.4 1 0 0 1 1 1 1 NHR1 homology to TAF NHR2 PF08788.11 KFQ93345.1 - 4e-16 58.5 2.2 1.2e-15 57.0 2.2 1.9 1 0 0 1 1 1 1 NHR2 domain like zf-MYND PF01753.18 KFQ93345.1 - 3.1e-07 30.4 18.8 3.1e-07 30.4 18.8 2.1 2 0 0 2 2 2 1 MYND finger Efg1 PF10153.9 KFQ93345.1 - 0.005 17.2 1.1 0.015 15.6 1.1 1.8 1 0 0 1 1 1 1 rRNA-processing protein Efg1 vATP-synt_E PF01991.18 KFQ93345.1 - 2.8 7.3 10.0 4.1 6.8 10.0 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit RRM_1 PF00076.22 KFQ93346.1 - 3.5e-17 62.0 0.0 5.9e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFQ93346.1 - 0.013 15.4 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RL PF17797.1 KFQ93346.1 - 0.036 14.0 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 RL domain Sedlin_N PF04628.13 KFQ93347.1 - 2.6e-33 114.9 0.9 3e-33 114.8 0.9 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KFQ93347.1 - 3.8e-10 39.9 0.2 4.6e-10 39.6 0.2 1.1 1 0 0 1 1 1 1 Sybindin-like family Sulfatase PF00884.23 KFQ93348.1 - 4e-86 289.2 0.0 5.4e-86 288.8 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KFQ93348.1 - 2e-32 112.6 0.0 3.6e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 KFQ93348.1 - 3.7e-10 40.0 0.1 2.8e-09 37.0 0.1 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KFQ93348.1 - 0.011 14.4 0.0 0.014 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) TFIIIC_delta PF12657.7 KFQ93348.1 - 0.099 12.6 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term Pribosyltran PF00156.27 KFQ93349.1 - 8.6e-23 80.6 0.0 1e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KFQ93349.1 - 0.00084 18.8 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KFQ93349.1 - 0.041 13.4 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase CDT1 PF08839.11 KFQ93350.1 - 3.3e-54 183.8 3.1 1.8e-53 181.4 3.1 1.9 1 1 0 1 1 1 1 DNA replication factor CDT1 like zf-Di19 PF05605.12 KFQ93351.1 - 7.3e-18 64.6 15.6 3.4e-17 62.5 3.7 2.7 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf_C2HC_14 PF18574.1 KFQ93351.1 - 1.7e-14 53.3 3.5 5.9e-14 51.6 3.5 2.0 1 0 0 1 1 1 1 C2HC Zing finger domain UIM PF02809.20 KFQ93351.1 - 0.00087 19.0 3.7 0.0014 18.4 3.7 1.4 1 0 0 1 1 1 1 Ubiquitin interaction motif Rubredoxin PF00301.20 KFQ93351.1 - 0.0012 18.9 1.7 4.9 7.3 0.0 3.4 3 0 0 3 3 3 1 Rubredoxin zinc_ribbon_2 PF13240.6 KFQ93351.1 - 0.024 14.3 0.2 0.024 14.3 0.2 4.3 5 0 0 5 5 5 0 zinc-ribbon domain zf-CHCC PF10276.9 KFQ93351.1 - 0.038 14.0 0.4 1.9 8.6 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger domain zf-ribbon_3 PF13248.6 KFQ93351.1 - 0.069 12.6 0.0 0.069 12.6 0.0 4.2 5 0 0 5 5 5 0 zinc-ribbon domain zf-C2H2_9 PF16293.5 KFQ93351.1 - 0.14 12.0 10.0 1.3 9.0 0.3 3.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2_4 PF13894.6 KFQ93351.1 - 0.29 12.1 0.6 0.29 12.1 0.6 5.2 5 1 0 5 5 4 0 C2H2-type zinc finger Cmc1 PF08583.10 KFQ93351.1 - 0.59 10.2 5.1 7 6.8 0.7 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like zinc_ribbon_10 PF10058.9 KFQ93351.1 - 1.1 9.0 0.1 1.1 9.0 0.1 3.2 4 0 0 4 4 4 0 Predicted integral membrane zinc-ribbon metal-binding protein DZR PF12773.7 KFQ93351.1 - 3.6 7.7 23.3 0.078 13.0 3.0 3.5 2 2 1 3 3 3 0 Double zinc ribbon zf-P11 PF03854.14 KFQ93351.1 - 5 6.9 10.0 1.3 8.8 5.1 2.5 2 0 0 2 2 2 0 P-11 zinc finger Rad50_zn_hook PF04423.14 KFQ93351.1 - 8.6 6.3 13.5 0.56 10.1 0.3 3.2 2 1 1 3 3 3 0 Rad50 zinc hook motif Actin_micro PF17003.5 KFQ93351.1 - 8.6 5.4 6.7 4.2 6.5 0.9 2.6 2 1 0 2 2 2 0 Putative actin-like family zf-C4pol PF14260.6 KFQ93351.1 - 9.1 6.8 15.7 1.1 9.8 6.5 2.8 2 2 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta zf-H2C2_2 PF13465.6 KFQ93351.1 - 9.3 6.9 15.1 1.4 9.5 0.7 4.2 4 0 0 4 4 4 0 Zinc-finger double domain Cytochrom_B558a PF05038.13 KFQ93352.1 - 8.9e-50 168.8 13.4 4.3e-26 91.6 0.4 2.0 1 1 1 2 2 2 2 Cytochrome Cytochrome b558 alpha-subunit DUF998 PF06197.13 KFQ93352.1 - 0.05 13.2 0.4 0.067 12.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) zf-CCCH_4 PF18044.1 KFQ93353.1 - 1.4e-08 34.4 5.2 2e-08 33.8 5.2 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFQ93353.1 - 1.8e-05 24.6 7.0 3e-05 23.9 7.0 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KFQ93353.1 - 0.00035 20.4 3.2 0.00061 19.6 3.2 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KFQ93353.1 - 0.0045 17.7 0.0 0.0045 17.7 0.0 2.8 2 0 0 2 2 2 1 Torus domain zf-CCCH_2 PF14608.6 KFQ93353.1 - 0.51 10.9 6.4 0.85 10.2 6.4 1.3 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger CIDE-N PF02017.15 KFQ93354.1 - 4.8e-28 97.0 0.0 6.6e-28 96.5 0.0 1.2 1 0 0 1 1 1 1 CIDE-N domain DUF4230 PF14014.6 KFQ93354.1 - 0.21 11.9 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) zf-C2H2 PF00096.26 KFQ93355.1 - 4.1e-07 30.1 22.8 0.0062 16.9 3.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ93355.1 - 1.5e-05 25.5 24.9 0.0045 17.7 1.4 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFQ93355.1 - 0.0018 18.6 10.9 0.0018 18.6 10.9 2.4 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) Zn_ribbon_SprT PF17283.2 KFQ93355.1 - 0.051 13.5 2.2 0.17 11.8 2.2 1.9 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zf-met PF12874.7 KFQ93355.1 - 1.4 9.4 12.7 0.077 13.4 1.8 3.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-MYST PF17772.1 KFQ93355.1 - 2.2 7.9 18.1 0.84 9.3 1.6 3.7 2 2 2 4 4 4 0 MYST family zinc finger domain Actin_micro PF17003.5 KFQ93355.1 - 5.5 6.1 13.2 4.9 6.2 4.9 2.3 1 1 1 2 2 2 0 Putative actin-like family zf-C2HE PF16278.5 KFQ93355.1 - 7.7 7.1 18.5 3 8.4 1.8 3.7 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger BEN PF10523.9 KFQ93356.1 - 4.2e-08 33.3 0.0 1e-06 28.9 0.0 2.5 2 0 0 2 2 2 1 BEN domain Secretin_N_2 PF07655.13 KFQ93356.1 - 4.8 7.8 12.0 9.9 6.8 3.1 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain Carb_anhydrase PF00194.21 KFQ93357.1 - 3.6e-85 285.6 0.0 4.2e-85 285.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Tudor_3 PF18115.1 KFQ93357.1 - 0.019 14.8 0.0 0.46 10.4 0.0 2.7 3 0 0 3 3 3 0 DNA repair protein Crb2 Tudor domain AA_permease_2 PF13520.6 KFQ93358.1 - 4.8e-65 220.1 43.3 5.5e-65 219.9 43.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFQ93358.1 - 2.5e-27 95.6 38.8 3.4e-27 95.2 38.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4448 PF14610.6 KFQ93358.1 - 0.31 10.8 2.3 6.3 6.5 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) SirB PF04247.12 KFQ93358.1 - 0.64 10.1 10.6 0.16 12.1 1.2 2.8 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB Kelch_4 PF13418.6 KFQ93359.1 - 1.7e-39 133.6 0.1 4.9e-11 42.5 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 KFQ93359.1 - 1.2e-33 114.8 3.1 9.3e-08 32.2 0.1 7.5 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KFQ93359.1 - 4.3e-28 96.8 6.7 1.6e-07 31.1 0.2 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFQ93359.1 - 4.2e-27 93.5 2.2 8.1e-07 29.1 0.0 6.2 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KFQ93359.1 - 1.9e-19 68.8 14.2 3.5e-05 23.6 0.0 7.7 6 3 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 KFQ93359.1 - 1.2e-16 60.0 6.4 1.1e-05 24.9 0.0 7.1 6 1 0 6 6 6 4 Kelch motif DUF4110 PF13422.6 KFQ93359.1 - 0.00037 20.5 0.1 0.00037 20.5 0.1 3.3 3 1 1 4 4 4 1 Domain of unknown function (DUF4110) MORN PF02493.20 KFQ93360.1 - 1.2e-41 138.2 67.9 9.1e-10 37.9 0.9 8.6 8 0 0 8 8 8 8 MORN repeat zf-CCHC PF00098.23 KFQ93361.1 - 7.3e-06 25.8 2.2 7.3e-06 25.8 2.2 2.4 3 0 0 3 3 3 1 Zinc knuckle SAM_1 PF00536.30 KFQ93361.1 - 0.00029 21.2 0.6 0.00059 20.2 0.6 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFQ93361.1 - 0.024 14.7 0.3 0.048 13.8 0.3 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) ANAPC_CDC26 PF10471.9 KFQ93361.1 - 3.9 8.4 6.2 6.6 7.6 0.0 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Atg8 PF02991.16 KFQ93362.1 - 1e-43 147.8 0.2 1.1e-43 147.6 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KFQ93362.1 - 1.8e-06 28.3 0.0 2.2e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Rad60-SLD PF11976.8 KFQ93362.1 - 0.076 12.9 0.1 0.62 9.9 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Cytochrom_B559a PF00284.20 KFQ93362.1 - 0.16 11.8 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit DUF3506 PF12014.8 KFQ93363.1 - 0.00043 20.3 4.4 0.9 9.5 4.4 3.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) SBF2 PF12335.8 KFQ93364.1 - 8e-05 22.4 2.2 0.00019 21.1 0.2 2.2 2 1 0 2 2 2 1 Myotubularin protein DUF1754 PF08555.10 KFQ93364.1 - 2.1 9.2 11.2 0.11 13.3 3.0 2.3 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Sld5 PF05916.11 KFQ93365.1 - 2.6e-12 47.1 1.0 2.9e-12 47.0 1.0 1.0 1 0 0 1 1 1 1 GINS complex protein UPF0172 PF03665.13 KFQ93366.1 - 7.2e-45 153.4 0.2 8.1e-45 153.2 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) COX4 PF02936.14 KFQ93367.1 - 4.8e-58 195.1 0.3 5.5e-58 194.9 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DSPc PF00782.20 KFQ93368.1 - 2e-27 95.6 0.0 2.4e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFQ93368.1 - 0.00041 20.0 0.1 0.00046 19.8 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KFQ93368.1 - 0.0083 16.3 0.5 0.014 15.5 0.1 1.7 2 0 0 2 2 2 1 Inositol hexakisphosphate IRF-3 PF10401.9 KFQ93369.1 - 8.2e-67 224.5 0.1 1.1e-66 224.0 0.1 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.17 KFQ93369.1 - 9.6e-43 144.8 0.6 1.8e-42 143.9 0.6 1.5 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor MH2 PF03166.14 KFQ93369.1 - 0.00097 19.4 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 MH2 domain 5-FTHF_cyc-lig PF01812.20 KFQ93371.1 - 3.1e-24 85.9 0.0 4.5e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family RRM_1 PF00076.22 KFQ93371.1 - 3e-05 23.8 0.0 9.7e-05 22.1 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bee_toxin PF17454.2 KFQ93371.1 - 0.036 14.1 0.1 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Honey bee toxin Forkhead PF00250.18 KFQ93372.1 - 6.6e-42 141.7 0.1 7.5e-42 141.5 0.1 1.0 1 0 0 1 1 1 1 Forkhead domain Forkhead PF00250.18 KFQ93373.1 - 1.8e-40 137.1 0.0 2e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Forkhead domain DHHC PF01529.20 KFQ93376.1 - 4e-36 124.1 13.5 4e-36 124.1 13.5 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF3615 PF12274.8 KFQ93376.1 - 0.29 11.7 4.1 0.62 10.6 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3615) TRIQK PF15168.6 KFQ93376.1 - 0.32 10.9 3.2 4.5 7.2 0.1 2.6 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family DUF4191 PF13829.6 KFQ93376.1 - 3 7.1 3.8 5.4 6.3 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Hormone_recep PF00104.30 KFQ93377.1 - 5.3e-39 133.9 0.2 1.2e-38 132.8 0.0 1.6 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFQ93377.1 - 3.2e-30 104.4 18.1 5.2e-30 103.7 18.1 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) LCCL PF03815.19 KFQ93378.1 - 2.6e-50 168.5 10.3 1.9e-26 92.0 0.1 2.9 3 0 0 3 3 3 2 LCCL domain CAP PF00188.26 KFQ93378.1 - 1.9e-21 77.2 5.5 3.3e-21 76.4 5.5 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Rxt3 PF08642.10 KFQ93378.1 - 3.2e-05 24.7 0.0 0.0092 16.7 0.0 2.6 2 0 0 2 2 2 2 Histone deacetylation protein Rxt3 DUF5607 PF18355.1 KFQ93378.1 - 0.0067 16.8 0.1 0.018 15.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5607) UCH PF00443.29 KFQ93379.1 - 7.7e-39 133.7 0.0 1.1e-38 133.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFQ93379.1 - 2.2e-07 30.8 0.0 3.4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PAM2 PF07145.15 KFQ93379.1 - 3.3e-05 23.3 0.0 9.5e-05 21.8 0.0 1.9 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Kelch_1 PF01344.25 KFQ93380.1 - 1.8e-42 142.7 11.1 1.1e-09 37.7 0.1 6.3 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KFQ93380.1 - 2.3e-32 110.2 3.3 6.5e-05 23.1 0.1 6.5 4 2 2 6 6 6 6 Kelch motif BTB PF00651.31 KFQ93380.1 - 2.3e-27 95.4 0.8 1.3e-26 93.0 0.0 2.5 2 1 1 3 3 3 1 BTB/POZ domain Kelch_2 PF07646.15 KFQ93380.1 - 1.6e-22 78.6 5.7 8.9e-05 22.3 0.3 6.6 6 0 0 6 6 6 4 Kelch motif BACK PF07707.15 KFQ93380.1 - 2.3e-21 75.8 0.3 4.5e-21 74.9 0.3 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 KFQ93380.1 - 3e-20 72.0 2.5 0.0048 16.9 0.1 5.6 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KFQ93380.1 - 1.1e-14 54.3 0.9 0.31 11.4 0.2 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFQ93380.1 - 1.3e-14 53.7 2.0 1.3e-05 25.1 0.1 5.4 5 0 0 5 5 5 3 Kelch motif Cofilin_ADF PF00241.20 KFQ93381.1 - 1.5e-20 73.2 0.1 1.8e-20 73.0 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein TLD PF07534.16 KFQ93383.1 - 1e-37 129.5 0.2 1.5e-37 128.9 0.2 1.3 1 0 0 1 1 1 1 TLD E1-E2_ATPase PF00122.20 KFQ93384.1 - 3.8e-51 173.2 0.1 3.8e-51 173.2 0.1 2.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFQ93384.1 - 8.5e-43 146.2 7.1 8.5e-43 146.2 7.1 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 KFQ93384.1 - 4.4e-19 67.9 0.1 9.9e-19 66.8 0.1 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KFQ93384.1 - 1e-15 58.6 3.3 6.2e-15 56.1 3.3 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFQ93384.1 - 3.4e-15 55.9 0.2 2e-14 53.4 0.1 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFQ93384.1 - 0.00023 21.0 2.5 0.00051 19.8 2.5 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3784 PF12650.7 KFQ93384.1 - 0.45 10.7 7.7 5.6 7.2 0.4 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF3784) WAP PF00095.21 KFQ93385.1 - 2e-06 28.1 15.1 2e-06 28.1 15.1 2.3 2 0 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Ion_trans PF00520.31 KFQ93386.1 - 6.9e-39 133.5 3.4 9.5e-39 133.1 3.4 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFQ93386.1 - 4.9e-25 87.7 0.0 1.2e-24 86.4 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFQ93386.1 - 1.8e-12 47.1 4.8 2e-12 46.9 2.5 2.2 2 0 0 2 2 2 1 Ion channel CECR6_TMEM121 PF14997.6 KFQ93386.1 - 0.053 13.3 0.6 0.11 12.3 0.4 1.7 1 1 0 1 1 1 0 CECR6/TMEM121 family MCD PF05292.11 KFQ93387.1 - 3e-23 82.7 0.4 4.1e-23 82.3 0.2 1.3 2 0 0 2 2 2 1 Malonyl-CoA decarboxylase C-terminal domain fn3 PF00041.21 KFQ93388.1 - 5.3e-08 33.1 0.0 1e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain zf-B_box PF00643.24 KFQ93388.1 - 4.1e-07 30.0 4.9 4.1e-07 30.0 4.9 7.6 6 2 0 6 6 6 2 B-box zinc finger AbiGii_2 PF16873.5 KFQ93388.1 - 0.00046 19.0 1.8 0.00079 18.3 1.8 1.3 1 0 0 1 1 1 1 Putative abortive phage resistance protein AbiGii toxin Pur_ac_phosph_N PF16656.5 KFQ93388.1 - 0.016 15.7 0.0 0.033 14.8 0.0 1.5 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain DUF3300 PF11737.8 KFQ93388.1 - 0.048 13.2 0.1 0.087 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) Nitrate_red_del PF02613.15 KFQ93388.1 - 0.17 11.9 1.0 1 9.4 0.5 2.2 1 1 1 2 2 2 0 Nitrate reductase delta subunit Cadherin PF00028.17 KFQ93389.1 - 5.9e-16 58.7 0.2 4.2e-10 39.9 0.5 2.7 2 0 0 2 2 2 2 Cadherin domain Laminin_G_3 PF13385.6 KFQ93389.1 - 0.0004 20.6 0.0 0.00069 19.8 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily V_ATPase_I PF01496.19 KFQ93389.1 - 0.001 17.1 1.7 0.0016 16.4 1.7 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family TMEM132D_C PF15706.5 KFQ93389.1 - 0.0049 16.6 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Myc_N PF01056.18 KFQ93389.1 - 0.0066 16.4 5.5 0.01 15.8 5.5 1.3 1 0 0 1 1 1 1 Myc amino-terminal region SpoIIIAH PF12685.7 KFQ93389.1 - 0.0091 15.8 2.5 0.014 15.2 2.5 1.2 1 0 0 1 1 1 1 SpoIIIAH-like protein Chordopox_A13L PF05961.11 KFQ93389.1 - 0.035 14.3 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Chordopoxvirus A13L protein LRR19-TM PF15176.6 KFQ93389.1 - 0.54 10.3 6.0 1.6 8.7 6.0 1.8 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain SDA1 PF05285.12 KFQ93389.1 - 0.57 9.6 12.5 0.82 9.0 12.5 1.1 1 0 0 1 1 1 0 SDA1 CTP_transf_like PF01467.26 KFQ93390.1 - 6.9e-36 123.6 0.0 4.3e-35 121.0 0.0 1.9 1 1 0 1 1 1 1 Cytidylyltransferase-like DUF3574 PF12098.8 KFQ93390.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) Lipocalin PF00061.23 KFQ93391.1 - 6.8e-18 65.3 0.3 8.1e-18 65.0 0.3 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 KFQ93391.1 - 2.5e-05 24.2 0.2 3.1e-05 23.9 0.2 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.23 KFQ93392.1 - 2.1e-18 66.9 5.9 2.3e-18 66.8 5.9 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 KFQ93392.1 - 3.4e-07 30.2 0.7 4e-07 30.0 0.7 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Coatomer_WDAD PF04053.14 KFQ93393.1 - 2.1e-170 567.6 0.0 3.7e-170 566.8 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 KFQ93393.1 - 3.7e-41 138.3 8.1 1.4e-09 38.4 0.1 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ93393.1 - 4.9e-07 30.0 0.5 0.64 10.4 0.1 6.2 4 3 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain MetallophosC PF16370.5 KFQ93393.1 - 0.073 13.3 0.0 0.6 10.3 0.0 2.2 1 1 1 2 2 2 0 C terminal of Calcineurin-like phosphoesterase Forkhead PF00250.18 KFQ93394.1 - 4.7e-39 132.5 0.0 7.1e-39 132.0 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain PI3Ka PF00613.20 KFQ93395.1 - 3.4e-62 209.1 1.2 7.5e-62 208.0 1.2 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KFQ93395.1 - 8.3e-60 202.7 0.0 1.9e-59 201.5 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_p85B PF02192.16 KFQ93395.1 - 3.4e-33 113.2 0.1 1.2e-32 111.4 0.1 2.0 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain PI3K_rbd PF00794.18 KFQ93395.1 - 3.7e-31 107.4 0.1 8.9e-31 106.2 0.1 1.7 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 KFQ93395.1 - 6.5e-20 71.5 0.0 1.3e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 RWD PF05773.22 KFQ93395.1 - 0.0044 17.3 0.9 1.3 9.3 0.1 3.0 3 0 0 3 3 3 2 RWD domain DUF4135 PF13575.6 KFQ93395.1 - 0.034 13.5 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Synaptobrevin PF00957.21 KFQ93397.1 - 1.4e-21 76.1 1.0 1.5e-21 76.0 1.0 1.0 1 0 0 1 1 1 1 Synaptobrevin Seryl_tRNA_N PF02403.22 KFQ93397.1 - 0.029 14.6 0.2 0.033 14.4 0.2 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Period_C PF12114.8 KFQ93398.1 - 1.4e-93 311.9 6.3 1.4e-93 311.9 6.3 4.0 4 1 0 4 4 4 1 Period protein 2/3C-terminal region PAS_3 PF08447.12 KFQ93398.1 - 1.6e-12 47.5 0.0 5.2e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 KFQ93398.1 - 1.3e-08 35.0 0.0 5.7e-08 32.9 0.0 2.2 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 KFQ93398.1 - 8.4e-06 25.8 0.0 0.00038 20.4 0.0 2.7 2 0 0 2 2 2 1 PAS fold HLH PF00010.26 KFQ93399.1 - 5.3e-16 58.3 2.2 1.1e-15 57.3 2.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 KFQ93399.1 - 1.2e-11 44.6 0.1 2.6e-11 43.5 0.1 1.6 1 0 0 1 1 1 1 Hairy Orange Mo25 PF08569.11 KFQ93400.1 - 9.1e-143 475.5 16.5 1e-142 475.3 16.5 1.0 1 0 0 1 1 1 1 Mo25-like BRICHOS PF04089.14 KFQ93401.1 - 2.9e-22 78.7 0.0 4.6e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 BRICHOS domain 7tm_1 PF00001.21 KFQ93402.1 - 1.5e-32 113.0 26.7 1.7e-32 112.8 26.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CAML PF14963.6 KFQ93402.1 - 0.5 10.5 1.9 0.84 9.7 1.9 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand 7tm_1 PF00001.21 KFQ93403.1 - 6.1e-33 114.3 17.5 7.6e-33 113.9 17.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 KFQ93404.1 - 1.7e-28 99.7 27.9 2e-28 99.5 27.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 KFQ93405.1 - 3.1e-22 79.1 12.0 4.1e-22 78.8 12.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ93405.1 - 0.00069 19.1 4.7 0.0009 18.7 4.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DHHC PF01529.20 KFQ93405.1 - 7.2 6.7 12.6 0.2 11.7 0.4 2.2 1 1 1 2 2 2 0 DHHC palmitoyltransferase 7tm_1 PF00001.21 KFQ93406.1 - 6.5e-28 97.8 8.0 7.3e-28 97.6 8.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1201 PF06716.11 KFQ93406.1 - 4.8 7.3 12.5 0.15 12.1 4.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) Glyco_transf_29 PF00777.18 KFQ93407.1 - 7.7e-38 130.4 0.0 1.6e-37 129.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) C1q PF00386.21 KFQ93408.1 - 3.9e-40 137.0 0.5 4.8e-40 136.7 0.5 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFQ93408.1 - 9.3e-11 41.3 31.6 1.2e-09 37.8 31.6 2.2 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) BclA_C PF18573.1 KFQ93408.1 - 0.0014 18.5 0.0 0.002 18.1 0.0 1.1 1 0 0 1 1 1 1 BclA C-terminal domain PPV_E2_N PF00508.17 KFQ93408.1 - 0.069 12.5 0.2 0.1 12.0 0.2 1.2 1 0 0 1 1 1 0 E2 (early) protein, N terminal MYEOV2 PF15004.6 KFQ93409.1 - 4.8e-34 116.6 6.9 5.3e-34 116.5 6.9 1.0 1 0 0 1 1 1 1 Myeloma-overexpressed-like OTOS PF15182.6 KFQ93410.1 - 1.7e-27 95.1 2.8 1.8e-27 95.0 2.8 1.0 1 0 0 1 1 1 1 Otospiralin DUF4816 PF16086.5 KFQ93411.1 - 2.1 8.3 85.7 1.8e+04 -59.6 85.7 5.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4816) Glypican PF01153.19 KFQ93412.1 - 2e-109 366.9 2.7 2.2e-109 366.8 2.7 1.0 1 0 0 1 1 1 1 Glypican Fz PF01392.22 KFQ93412.1 - 0.042 14.5 0.4 0.042 14.5 0.4 2.2 2 0 0 2 2 2 0 Fz domain Spore_III_AB PF09548.10 KFQ93412.1 - 0.12 12.5 1.0 3.2 7.8 0.5 2.5 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Glypican PF01153.19 KFQ93413.1 - 5.3e-220 732.0 1.8 6.4e-220 731.7 1.8 1.0 1 0 0 1 1 1 1 Glypican Fz PF01392.22 KFQ93413.1 - 0.0034 18.0 0.4 0.01 16.4 0.4 1.8 1 0 0 1 1 1 1 Fz domain HU-CCDC81_euk_2 PF18289.1 KFQ93414.1 - 1.5e-20 73.1 0.0 1.9e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 DSPc PF00782.20 KFQ93415.1 - 5.8e-29 100.6 0.0 6.5e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KFQ93415.1 - 0.018 15.4 0.0 0.025 14.9 0.0 1.2 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KFQ93415.1 - 0.04 13.5 0.0 0.047 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPn PF14671.6 KFQ93415.1 - 0.13 12.7 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half PMP22_Claudin PF00822.20 KFQ93416.1 - 2e-34 118.9 13.2 2.5e-34 118.6 13.2 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFQ93416.1 - 4.7e-11 42.8 13.8 1.1e-10 41.6 13.8 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.11 KFQ93416.1 - 2.5 7.9 13.8 0.26 11.1 6.8 2.2 1 1 1 2 2 2 0 Amastin surface glycoprotein Rhomboid PF01694.22 KFQ93417.1 - 6.8e-27 94.3 15.2 1.1e-26 93.6 15.2 1.3 1 0 0 1 1 1 1 Rhomboid family Caps_synth_CapC PF14102.6 KFQ93417.1 - 0.81 10.1 6.7 0.2 12.1 3.3 1.8 2 0 0 2 2 2 0 Capsule biosynthesis CapC YEATS PF03366.16 KFQ93418.1 - 1.3e-25 89.2 0.7 3.5e-25 87.8 0.7 1.8 1 0 0 1 1 1 1 YEATS family Kelch_1 PF01344.25 KFQ93419.1 - 2.1e-44 148.8 24.5 8e-14 51.0 0.1 7.2 7 1 0 7 7 7 6 Kelch motif BACK PF07707.15 KFQ93419.1 - 2.2e-32 111.2 0.8 2.2e-32 111.2 0.8 1.6 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFQ93419.1 - 6.9e-29 99.2 8.7 1.8e-05 24.9 0.0 6.6 3 1 3 6 6 6 6 Kelch motif BTB PF00651.31 KFQ93419.1 - 1.8e-28 99.0 1.4 4e-28 97.9 0.7 2.0 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.6 KFQ93419.1 - 8.6e-26 89.7 3.6 5.2e-05 23.4 0.1 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 KFQ93419.1 - 3.2e-21 75.1 1.4 0.00031 20.7 0.0 7.0 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KFQ93419.1 - 9.9e-21 72.9 12.5 1.3e-05 24.9 0.1 6.6 6 1 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 KFQ93419.1 - 2.6e-08 33.7 9.0 0.094 12.7 0.1 5.8 6 0 0 6 6 6 2 Kelch motif DUF3342 PF11822.8 KFQ93419.1 - 0.0092 16.2 0.5 0.026 14.7 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) Kelch_1 PF01344.25 KFQ93420.1 - 3.1e-35 119.5 6.0 6.1e-12 44.9 0.1 6.9 6 1 0 6 6 6 5 Kelch motif BACK PF07707.15 KFQ93420.1 - 1.1e-31 109.0 0.3 2.4e-31 107.9 0.3 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFQ93420.1 - 4.8e-28 96.5 0.0 3e-05 24.1 0.0 6.1 4 2 2 6 6 6 5 Kelch motif BTB PF00651.31 KFQ93420.1 - 1.1e-27 96.4 5.0 4.2e-27 94.6 2.4 2.5 1 1 1 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 KFQ93420.1 - 7.9e-27 92.2 0.7 1.5e-05 24.7 0.1 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 KFQ93420.1 - 7.9e-14 51.5 1.3 0.014 15.6 0.0 6.3 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.6 KFQ93420.1 - 1.2e-13 50.8 0.2 0.1 12.6 0.0 6.4 5 2 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFQ93420.1 - 9.7e-11 41.4 1.6 0.00055 19.8 0.1 5.6 6 0 0 6 6 6 2 Kelch motif DUF3342 PF11822.8 KFQ93420.1 - 0.00022 21.3 3.2 0.0018 18.5 0.6 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3342) 7tm_1 PF00001.21 KFQ93421.1 - 2.9e-06 26.8 26.6 1e-05 25.0 26.5 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFQ93421.1 - 0.029 14.1 21.3 0.091 12.5 21.3 1.8 1 1 0 1 1 1 0 Olfactory receptor RhoGEF PF00621.20 KFQ93422.1 - 9.8e-47 159.5 6.6 9.8e-47 159.5 6.6 2.0 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 KFQ93422.1 - 1e-10 42.0 0.6 2.3e-10 40.9 0.6 1.6 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.28 KFQ93422.1 - 3.7e-10 39.2 1.9 6.8e-10 38.4 1.9 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFQ93422.1 - 3.6e-09 36.3 0.1 6.7e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFQ93422.1 - 1.3e-07 31.2 0.0 2.5e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_5 PF15405.6 KFQ93422.1 - 0.068 13.3 0.1 1 9.4 0.0 2.3 1 1 0 2 2 2 0 Pleckstrin homology domain Cor1 PF04803.12 KFQ93422.1 - 0.29 11.3 6.9 0.85 9.8 0.9 3.0 2 1 1 3 3 3 0 Cor1/Xlr/Xmr conserved region TCRP1 PF14944.6 KFQ93424.1 - 1.4e-108 362.5 66.0 4.7e-87 292.0 44.1 2.0 1 1 1 2 2 2 2 Tongue Cancer Chemotherapy Resistant Protein 1 PH PF00169.29 KFQ93425.1 - 1.9e-10 41.2 0.3 2.7e-10 40.7 0.3 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFQ93425.1 - 0.0025 18.2 0.4 0.0067 16.8 0.4 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain Sulfotransfer_2 PF03567.14 KFQ93426.1 - 6.9e-17 62.2 0.1 7.9e-17 62.0 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFQ93427.1 - 2e-48 165.5 0.5 3e-48 164.9 0.5 1.3 1 0 0 1 1 1 1 Sulfotransferase family NuA4 PF09340.10 KFQ93427.1 - 0.53 10.2 2.7 1.2 9.0 2.7 1.6 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 Glyco_transf_24 PF18404.1 KFQ93428.1 - 5.5e-148 491.6 5.5 6.8e-148 491.3 4.1 1.9 2 0 0 2 2 2 1 Glucosyltransferase 24 Thioredoxin_15 PF18403.1 KFQ93428.1 - 4.6e-72 242.4 2.8 2.1e-65 220.7 0.7 3.3 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_14 PF18402.1 KFQ93428.1 - 2.5e-67 227.5 10.7 1e-63 215.7 1.0 3.7 4 0 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KFQ93428.1 - 1.9e-54 184.5 0.1 1.3e-52 178.5 0.1 2.6 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KFQ93428.1 - 5.1e-40 136.0 0.0 1.5e-39 134.5 0.0 1.9 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 KFQ93428.1 - 9.7e-38 129.2 2.4 3.2e-37 127.5 0.3 2.8 3 0 0 3 3 3 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 KFQ93428.1 - 0.00016 21.3 4.1 0.00023 20.8 0.4 2.8 3 0 0 3 3 3 1 Glycosyl transferase family 8 AMMECR1 PF01871.17 KFQ93430.1 - 1e-47 161.8 0.0 1.3e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 RNA_pol_Rpb4 PF03874.16 KFQ93431.1 - 1.1e-26 93.5 5.9 1.3e-26 93.3 5.9 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Rop PF01815.16 KFQ93431.1 - 0.0082 16.0 0.8 0.015 15.1 0.2 1.8 2 0 0 2 2 2 1 Rop protein WD40 PF00400.32 KFQ93432.1 - 5.6e-32 109.3 14.5 1.8e-06 28.5 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ93432.1 - 3.1e-11 43.4 1.7 0.59 10.5 0.0 5.5 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Collagen PF01391.18 KFQ93432.1 - 3.2e-06 26.8 59.7 0.00011 21.8 26.5 9.7 6 1 2 8 8 8 2 Collagen triple helix repeat (20 copies) eIF2A PF08662.11 KFQ93432.1 - 1e-05 25.5 3.4 0.041 13.7 0.7 2.9 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFQ93432.1 - 0.00066 18.7 0.0 0.012 14.6 0.1 2.5 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF3292 PF11696.8 KFQ93432.1 - 3.1 6.1 5.2 4.6 5.5 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) LIM PF00412.22 KFQ93433.1 - 8.6e-62 205.2 59.6 1.5e-14 54.0 3.2 5.1 5 0 0 5 5 5 5 LIM domain 7tm_1 PF00001.21 KFQ93434.1 - 2.5e-50 171.3 17.3 2.5e-50 171.3 17.3 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ93434.1 - 5.9e-07 29.1 18.5 7.1e-07 28.9 18.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 KFQ93434.1 - 0.0002 20.8 15.4 0.0002 20.8 15.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 KFQ93434.1 - 0.0027 17.4 9.9 0.0027 17.4 9.9 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFQ93434.1 - 0.0029 17.4 7.6 0.0029 17.4 7.6 2.6 1 1 1 2 2 2 1 Olfactory receptor Srg PF02118.21 KFQ93434.1 - 0.017 14.8 19.5 0.015 15.0 18.2 1.5 1 1 0 1 1 1 0 Srg family chemoreceptor DUF5409 PF17421.2 KFQ93434.1 - 0.045 14.5 0.5 0.045 14.5 0.5 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5409) DUF983 PF06170.12 KFQ93434.1 - 0.56 10.6 0.1 0.56 10.6 0.1 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF983) TauE PF01925.19 KFQ93434.1 - 0.92 9.1 8.5 1.7 8.2 8.5 1.6 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE Med26 PF08711.11 KFQ93435.1 - 1.2e-14 54.0 0.2 4.6e-14 52.2 0.0 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Trypsin PF00089.26 KFQ93436.1 - 2.8e-61 207.2 0.0 3e-61 207.0 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFQ93436.1 - 0.00083 19.7 0.0 0.0018 18.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 KFQ93436.1 - 0.0011 19.9 0.0 0.0021 19.0 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain DAGK_acc PF00609.19 KFQ93437.1 - 2.4e-51 174.2 0.0 4.8e-51 173.3 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KFQ93437.1 - 2.1e-27 95.3 0.1 5.5e-27 93.9 0.0 1.8 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain SAM_2 PF07647.17 KFQ93437.1 - 2.9e-19 68.9 1.0 1.5e-18 66.7 0.2 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) C1_1 PF00130.22 KFQ93437.1 - 1.2e-18 66.7 28.2 8.6e-11 41.6 4.9 2.9 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) SAM_1 PF00536.30 KFQ93437.1 - 1.6e-17 63.7 2.6 9.1e-17 61.3 0.6 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH PF00169.29 KFQ93437.1 - 2.6e-15 56.8 1.3 6.7e-15 55.5 0.2 2.3 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 KFQ93437.1 - 0.00011 22.5 0.2 0.00025 21.3 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFQ93437.1 - 0.0016 18.8 6.3 0.0028 18.0 2.5 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain C1_2 PF03107.16 KFQ93437.1 - 0.0019 18.5 16.0 0.014 15.7 5.7 3.0 2 0 0 2 2 2 2 C1 domain Mcp5_PH PF12814.7 KFQ93437.1 - 0.0086 16.2 0.1 0.022 14.9 0.1 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Arrestin_N PF00339.29 KFQ93438.1 - 6.6e-38 130.0 0.2 2.9e-34 118.2 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KFQ93438.1 - 6.1e-26 91.5 1.1 9.1e-26 90.9 1.1 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain DUF2079 PF09852.9 KFQ93438.1 - 0.013 14.4 0.1 0.018 13.9 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) Transglut_C PF00927.22 KFQ93438.1 - 0.018 15.2 0.2 0.043 14.0 0.2 1.6 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain ATG16 PF08614.11 KFQ93439.1 - 5.8e-43 147.5 29.0 5.8e-43 147.5 29.0 1.9 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) WD40 PF00400.32 KFQ93439.1 - 4.9e-35 118.9 12.5 1.2e-06 29.1 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ93439.1 - 8.1e-10 38.9 0.1 0.0036 17.6 0.0 4.7 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFQ93439.1 - 2.2e-06 27.7 0.0 0.14 12.0 0.0 3.4 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFQ93439.1 - 1.8e-05 23.8 0.2 0.38 9.7 0.1 3.4 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFQ93439.1 - 0.0001 21.1 8.2 1.4 7.5 0.0 4.6 3 1 1 5 5 5 3 Nucleoporin Nup120/160 ZapB PF06005.12 KFQ93439.1 - 0.004 17.5 7.2 0.004 17.5 7.2 3.8 2 1 2 4 4 3 1 Cell division protein ZapB Fez1 PF06818.15 KFQ93439.1 - 0.0042 17.6 26.4 0.0078 16.7 26.4 1.4 1 0 0 1 1 1 1 Fez1 KASH_CCD PF14662.6 KFQ93439.1 - 0.013 15.4 12.7 0.013 15.4 12.7 3.0 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH V_ATPase_I PF01496.19 KFQ93439.1 - 0.031 12.2 11.7 0.04 11.8 11.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HTH_6 PF01418.17 KFQ93439.1 - 0.05 13.6 1.0 0.16 12.0 1.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Lipoprotein_6 PF01441.19 KFQ93439.1 - 0.063 13.3 4.7 0.12 12.4 4.4 1.6 1 1 0 1 1 1 0 Lipoprotein WD40_like PF17005.5 KFQ93439.1 - 0.072 12.4 0.0 0.54 9.5 0.0 2.3 3 1 0 3 3 3 0 WD40-like domain SGL PF08450.12 KFQ93439.1 - 0.082 12.5 0.1 0.3 10.6 0.0 1.9 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region ERM PF00769.19 KFQ93439.1 - 0.098 12.5 33.6 0.025 14.4 30.2 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family YicC_N PF03755.13 KFQ93439.1 - 0.53 10.7 9.0 1.1 9.7 9.0 1.6 1 0 0 1 1 1 0 YicC-like family, N-terminal region YabA PF06156.13 KFQ93439.1 - 0.91 10.2 22.2 0.18 12.5 7.6 2.8 1 1 1 2 2 2 0 Initiation control protein YabA FUSC PF04632.12 KFQ93439.1 - 1.5 7.3 11.2 2 6.8 11.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Atg14 PF10186.9 KFQ93439.1 - 1.5 7.8 15.5 3.1 6.8 15.5 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 NPV_P10 PF05531.12 KFQ93439.1 - 1.6 9.2 5.2 0.77 10.3 0.6 2.5 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Lebercilin PF15619.6 KFQ93439.1 - 1.7 8.3 34.8 3.2 7.4 34.8 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Synaptobrevin PF00957.21 KFQ93439.1 - 1.9 8.3 6.4 3 7.7 4.9 2.1 2 0 0 2 2 2 0 Synaptobrevin MRP-S27 PF10037.9 KFQ93439.1 - 2.5 6.9 18.8 3.7 6.3 18.8 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Allexi_40kDa PF05549.11 KFQ93439.1 - 2.9 7.3 8.5 4 6.9 7.2 1.7 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF812 PF05667.11 KFQ93439.1 - 3 6.6 28.2 4.2 6.2 28.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF1664 PF07889.12 KFQ93439.1 - 3.3 7.8 8.3 17 5.4 8.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 KFQ93439.1 - 3.5 8.2 41.4 4.9 7.7 22.3 3.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Phage_GPO PF05929.11 KFQ93439.1 - 3.7 7.1 17.4 0.93 9.1 12.7 2.1 1 1 2 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase FlaC_arch PF05377.11 KFQ93439.1 - 4.6 7.7 8.9 0.25 11.8 1.6 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TSC22 PF01166.18 KFQ93439.1 - 4.9 7.5 9.1 1.4 9.3 1.6 3.0 1 1 2 3 3 2 0 TSC-22/dip/bun family PKcGMP_CC PF16808.5 KFQ93439.1 - 7.2 6.6 11.8 0.31 10.9 2.2 3.2 2 1 1 3 3 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF724 PF05266.14 KFQ93439.1 - 8 6.2 21.4 0.21 11.4 13.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) HALZ PF02183.18 KFQ93439.1 - 8 6.8 13.2 0.36 11.1 5.0 3.2 2 2 1 3 3 2 0 Homeobox associated leucine zipper FapA PF03961.13 KFQ93439.1 - 9.1 4.8 20.0 1.5 7.4 15.2 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A SH2 PF00017.24 KFQ93440.1 - 1.3e-17 63.6 0.0 4.4e-17 62.0 0.0 2.0 1 0 0 1 1 1 1 SH2 domain Exo_endo_phos PF03372.23 KFQ93440.1 - 2.4e-09 37.0 0.0 4e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BNR_2 PF13088.6 KFQ93441.1 - 1e-37 129.9 0.0 1.4e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR_3 PF13859.6 KFQ93441.1 - 2.9e-05 23.5 0.0 3.6e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 KFQ93441.1 - 0.0025 17.5 6.3 0.21 11.7 0.2 3.6 4 0 0 4 4 4 2 BNR/Asp-box repeat RhoGEF PF00621.20 KFQ93442.1 - 1.7e-34 119.6 8.9 2.9e-34 118.9 8.9 1.4 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.28 KFQ93442.1 - 2.3e-12 46.3 0.0 6.5e-12 44.9 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFQ93442.1 - 2.5e-12 46.5 0.1 5.1e-12 45.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFQ93442.1 - 3e-07 30.0 0.0 7e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 KFQ93442.1 - 7.4e-06 26.4 0.3 8.8e-05 23.0 0.0 2.7 3 0 0 3 3 3 1 PH domain SesA PF17107.5 KFQ93442.1 - 0.011 15.9 0.6 0.044 14.0 0.6 2.0 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases SH3_16 PF18348.1 KFQ93442.1 - 0.041 13.7 0.0 0.34 10.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain DUF4690 PF15756.5 KFQ93443.1 - 1.9e-46 156.6 0.2 2.1e-46 156.4 0.2 1.0 1 0 0 1 1 1 1 Small Novel Rich in Cartilage GYF PF02213.16 KFQ93444.1 - 1.4e-21 75.8 0.7 3.2e-21 74.7 0.7 1.7 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KFQ93444.1 - 2e-06 27.5 0.1 8.1e-06 25.6 0.1 2.1 1 0 0 1 1 1 1 GYF domain 2 IRK PF01007.20 KFQ93445.1 - 1.4e-46 157.8 0.1 2.4e-46 157.0 0.1 1.4 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain IRK_C PF17655.1 KFQ93445.1 - 3.4e-35 121.2 0.0 4.5e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain Ion_trans_2 PF07885.16 KFQ93445.1 - 0.00015 21.6 3.3 0.00032 20.6 3.3 1.6 1 1 0 1 1 1 1 Ion channel EF-hand_1 PF00036.32 KFQ93446.1 - 2.6e-09 36.0 12.0 6.5e-06 25.3 0.9 3.0 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 KFQ93446.1 - 2.9e-09 37.2 1.0 2.9e-09 37.2 1.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KFQ93446.1 - 5.6e-09 35.2 2.7 1.5e-05 24.5 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KFQ93446.1 - 1.3e-06 27.7 1.7 0.037 13.5 0.4 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFQ93446.1 - 1.2e-05 25.0 6.9 0.031 14.1 0.7 2.7 2 1 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFQ93446.1 - 0.0088 16.4 0.2 0.028 14.8 0.0 1.8 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Myosin_N PF02736.19 KFQ93447.1 - 1.2e-12 47.4 0.4 1.8e-12 46.9 0.4 1.2 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain LRR_8 PF13855.6 KFQ93449.1 - 4.4e-53 176.9 75.7 3.7e-16 58.6 3.8 6.7 2 2 5 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 KFQ93449.1 - 6.2e-21 74.1 43.6 7.4e-07 29.4 0.6 7.5 6 1 4 10 10 10 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFQ93449.1 - 3.3e-17 62.7 0.0 2.2e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFQ93449.1 - 6.1e-08 32.4 13.3 0.031 13.8 0.2 4.2 2 2 2 4 4 4 4 Leucine-rich repeat LRRNT PF01462.18 KFQ93449.1 - 0.0023 17.6 0.8 0.0023 17.6 0.8 2.6 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KFQ93449.1 - 0.011 16.1 48.9 0.27 11.9 0.2 10.8 11 0 0 11 11 11 0 Leucine Rich Repeat Arm PF00514.23 KFQ93451.1 - 3.2e-88 287.4 17.5 1.8e-13 50.0 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KFQ93451.1 - 7.5e-27 93.6 6.6 1.5e-26 92.7 6.6 1.5 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 KFQ93451.1 - 4.3e-23 80.6 3.3 5.6e-23 80.3 1.5 2.1 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.6 KFQ93451.1 - 2.1e-17 63.3 0.0 8.1e-07 29.3 0.0 4.8 2 1 3 6 6 5 3 HEAT repeats HEAT_EZ PF13513.6 KFQ93451.1 - 1.3e-13 51.1 7.1 2.3e-05 24.8 0.0 5.9 4 2 1 5 5 5 3 HEAT-like repeat HEAT PF02985.22 KFQ93451.1 - 2.1e-11 43.0 6.9 0.0024 18.0 0.0 7.6 9 1 0 9 9 8 3 HEAT repeat RICTOR_V PF14668.6 KFQ93451.1 - 2e-05 24.7 1.5 0.29 11.4 0.0 4.8 4 1 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.8 KFQ93451.1 - 2.3e-05 24.4 0.3 0.092 12.9 0.1 4.0 3 3 1 4 4 4 2 V-ATPase subunit H Arm_2 PF04826.13 KFQ93451.1 - 0.00017 21.2 0.5 0.34 10.3 0.2 3.2 3 1 1 4 4 4 2 Armadillo-like V-ATPase_H_N PF03224.14 KFQ93451.1 - 0.0017 17.7 0.3 0.5 9.6 0.0 3.3 2 1 1 3 3 3 1 V-ATPase subunit H DUF3361 PF11841.8 KFQ93451.1 - 0.019 14.9 4.3 11 5.9 0.1 3.9 4 1 1 5 5 5 0 Domain of unknown function (DUF3361) Atx10homo_assoc PF09759.9 KFQ93451.1 - 0.021 14.9 0.1 0.46 10.5 0.0 2.7 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Moulting_cycle PF04870.16 KFQ93451.1 - 0.027 13.7 1.5 0.044 13.1 1.5 1.2 1 0 0 1 1 1 0 Moulting cycle HEAT_PBS PF03130.16 KFQ93451.1 - 2.2 9.2 7.9 11 7.1 0.3 5.0 6 1 0 6 6 5 0 PBS lyase HEAT-like repeat DUF1075 PF06388.11 KFQ93452.1 - 4.9e-50 168.6 0.1 6.1e-50 168.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1075) Cid2 PF09774.9 KFQ93453.1 - 3.4e-13 50.3 4.3 1e-11 45.5 4.3 2.0 1 1 0 1 1 1 1 Caffeine-induced death protein 2 Orbi_VP5 PF00901.17 KFQ93453.1 - 0.04 12.3 0.5 0.042 12.3 0.5 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 FOXP-CC PF16159.5 KFQ93453.1 - 1 10.0 5.8 24 5.6 0.2 2.2 1 1 1 2 2 2 0 FOXP coiled-coil domain Cystatin PF00031.21 KFQ93454.1 - 4.1e-20 71.8 0.1 4.6e-20 71.7 0.1 1.0 1 0 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 KFQ93454.1 - 0.062 13.7 0.1 0.079 13.3 0.1 1.2 1 0 0 1 1 1 0 Aspartic acid proteinase inhibitor Cystatin PF00031.21 KFQ93455.1 - 7.6e-16 58.2 0.1 8.3e-16 58.0 0.1 1.0 1 0 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 KFQ93455.1 - 0.038 14.3 0.0 0.041 14.2 0.0 1.2 1 0 0 1 1 1 0 Aspartic acid proteinase inhibitor Connexin40_C PF16791.5 KFQ93455.1 - 0.073 14.3 0.0 0.074 14.3 0.0 1.1 1 0 0 1 1 1 0 Connexin 40 C-terminal domain ANF_receptor PF01094.28 KFQ93456.1 - 1.3e-108 363.3 0.0 1.6e-108 362.9 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 KFQ93456.1 - 4.2e-65 219.8 30.9 8e-65 218.9 30.9 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 KFQ93456.1 - 1.5e-17 63.3 11.9 4.2e-17 61.9 11.9 1.8 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.6 KFQ93456.1 - 3.3e-12 46.7 0.0 1.6e-10 41.2 0.0 2.7 2 1 0 2 2 2 1 Periplasmic binding protein Ephrin_rec_like PF07699.13 KFQ93456.1 - 0.019 14.7 8.8 0.058 13.2 8.8 1.8 1 0 0 1 1 1 0 Putative ephrin-receptor like DUF2614 PF11023.8 KFQ93456.1 - 1.5 8.9 6.4 0.3 11.2 0.8 2.6 2 0 0 2 2 2 0 Zinc-ribbon containing domain Ig_3 PF13927.6 KFQ93458.1 - 4.8e-08 33.5 1.9 0.0026 18.3 0.5 3.2 2 1 1 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 KFQ93458.1 - 3.8e-07 30.1 1.7 1.7e-06 28.0 1.7 2.0 1 1 1 2 2 2 1 CD80-like C2-set immunoglobulin domain ig PF00047.25 KFQ93458.1 - 5.8e-06 26.4 1.4 0.038 14.2 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFQ93458.1 - 0.00015 21.9 2.6 0.00087 19.4 0.1 2.5 2 1 0 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.16 KFQ93458.1 - 0.00026 21.0 0.5 0.022 14.8 0.1 2.9 2 1 1 3 3 3 1 Immunoglobulin I-set domain C1-set PF07654.15 KFQ93458.1 - 0.0023 18.3 3.5 0.0098 16.2 0.3 2.9 2 2 0 2 2 2 1 Immunoglobulin C1-set domain Glyco_hydro_47 PF01532.20 KFQ93459.1 - 2.1e-157 524.7 0.0 2.6e-157 524.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Apolipoprotein PF01442.18 KFQ93459.1 - 1.3 8.9 5.2 0.98 9.3 2.9 1.8 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain zf-H2C2_2 PF13465.6 KFQ93460.1 - 2.1e-09 37.4 7.9 0.0023 18.3 0.0 3.2 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ93460.1 - 1.6e-07 31.4 11.0 7.3e-06 26.2 4.3 2.4 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ93460.1 - 5.5e-05 23.7 8.8 0.00044 20.8 2.9 2.5 2 1 0 2 2 2 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KFQ93460.1 - 0.0036 16.9 1.0 0.56 9.9 0.1 2.1 1 1 1 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_6 PF13912.6 KFQ93460.1 - 0.0057 16.6 1.7 0.0057 16.6 1.7 2.4 3 0 0 3 3 3 1 C2H2-type zinc finger Sel_put PF04328.13 KFQ93460.1 - 0.14 12.2 0.8 14 5.8 0.2 2.3 2 0 0 2 2 2 0 Selenoprotein, putative FMN_dh PF01070.18 KFQ93461.1 - 2e-133 444.7 0.0 2.3e-133 444.5 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KFQ93461.1 - 7.9e-08 31.7 1.5 3.8e-07 29.4 0.8 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFQ93461.1 - 1.9e-05 24.0 0.1 2.7e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KFQ93461.1 - 0.00097 18.7 0.2 0.0037 16.7 0.1 2.0 2 1 1 3 3 3 1 Histidine biosynthesis protein ThiG PF05690.14 KFQ93461.1 - 0.021 14.1 0.1 0.57 9.5 0.1 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG G3P_antiterm PF04309.12 KFQ93461.1 - 0.031 13.7 0.0 6.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator NMO PF03060.15 KFQ93461.1 - 0.064 12.6 0.8 0.1 12.0 0.8 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase DHO_dh PF01180.21 KFQ93461.1 - 0.1 11.8 0.1 0.2 10.8 0.1 1.4 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase tRNA-synt_1b PF00579.25 KFQ93462.1 - 1.5e-67 228.0 0.0 1.9e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Occludin_ELL PF07303.13 KFQ93462.1 - 0.017 15.9 0.1 0.88 10.3 0.0 2.2 2 0 0 2 2 2 0 Occludin homology domain T-box PF00907.22 KFQ93463.1 - 1.1e-07 32.4 0.0 1.3e-07 32.1 0.0 1.1 1 0 0 1 1 1 1 T-box T-box PF00907.22 KFQ93464.1 - 2.5e-53 181.1 0.1 2.8e-53 180.9 0.1 1.0 1 0 0 1 1 1 1 T-box Glyco_hydro_36C PF16874.5 KFQ93464.1 - 0.042 14.3 0.0 0.077 13.5 0.0 1.7 1 1 0 1 1 1 0 Glycosyl hydrolase family 36 C-terminal domain PapD-like PF14874.6 KFQ93465.1 - 3.6e-10 39.9 0.0 1.1e-09 38.4 0.0 1.7 2 0 0 2 2 2 1 Flagellar-associated PapD-like WD40 PF00400.32 KFQ93466.1 - 9.8e-58 190.8 17.5 6.1e-09 36.4 0.1 10.9 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.12 KFQ93466.1 - 9.9e-21 74.1 0.6 9.9e-21 74.1 0.6 1.7 2 0 0 2 2 2 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KFQ93466.1 - 8.7e-20 70.8 5.1 8e-05 22.9 0.0 8.9 4 3 7 11 11 11 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFQ93466.1 - 4.9e-08 32.7 0.0 0.0021 17.4 0.0 3.8 3 1 0 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 KFQ93466.1 - 2.3e-06 26.8 1.7 4.4 6.2 0.0 6.7 4 2 4 8 8 8 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KFQ93466.1 - 0.015 14.1 0.4 6.2 5.5 0.0 3.7 4 0 0 4 4 4 0 Nup133 N terminal like Nup160 PF11715.8 KFQ93466.1 - 0.04 12.6 1.9 5.2 5.6 0.0 4.2 5 0 0 5 5 5 0 Nucleoporin Nup120/160 ELFV_dehydrog PF00208.21 KFQ93466.1 - 0.3 10.8 1.5 0.58 9.8 1.5 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase RcpC PF16976.5 KFQ93466.1 - 1.5 8.9 4.1 32 4.6 0.0 3.4 3 0 0 3 3 3 0 Flp pilus assembly protein RcpC/CpaB CRAL_TRIO_2 PF13716.6 KFQ93467.1 - 1.8e-32 112.4 1.8 3.2e-32 111.6 1.8 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Macro PF01661.21 KFQ93467.1 - 3e-27 95.0 0.0 5.4e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Macro domain CRAL_TRIO PF00650.20 KFQ93467.1 - 4.3e-07 29.8 0.8 1e-06 28.5 0.8 1.7 1 0 0 1 1 1 1 CRAL/TRIO domain Epimerase_2 PF02350.19 KFQ93467.1 - 0.057 12.3 0.0 0.095 11.5 0.0 1.3 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase NTP_transf_7 PF07984.12 KFQ93468.1 - 9.8e-156 517.9 0.8 1.1e-155 517.7 0.8 1.0 1 0 0 1 1 1 1 Nucleotidyltransferase Zn_ribbon_SprT PF17283.2 KFQ93469.1 - 0.15 12.0 6.7 0.67 9.9 0.5 3.3 3 0 0 3 3 3 0 SprT-like zinc ribbon domain DZR PF12773.7 KFQ93469.1 - 0.89 9.6 7.0 39 4.4 7.0 2.7 1 1 0 1 1 1 0 Double zinc ribbon ATP-synt_ab PF00006.25 KFQ93470.1 - 8.2e-103 342.6 0.0 1e-102 342.3 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Acetyltransf_1 PF00583.25 KFQ93471.1 - 3.5e-14 53.0 0.0 4.4e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFQ93471.1 - 1.4e-09 38.2 0.1 1.9e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFQ93471.1 - 6.4e-09 35.8 0.0 7.9e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFQ93471.1 - 1.9e-05 24.8 0.1 2.9e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFQ93471.1 - 0.0002 21.2 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KFQ93471.1 - 0.0011 19.0 0.0 0.0019 18.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KFQ93471.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KFQ93471.1 - 0.026 15.2 0.0 0.032 14.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Nudix_hydro PF18290.1 KFQ93471.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Nudix hydrolase domain HLH PF00010.26 KFQ93472.1 - 1.6e-10 40.8 0.5 3.8e-10 39.6 0.5 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RsgA_GTPase PF03193.16 KFQ93472.1 - 0.029 14.3 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase SID-1_RNA_chan PF13965.6 KFQ93473.1 - 1.2e-288 958.6 15.6 1.4e-288 958.4 15.6 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 GWT1 PF06423.12 KFQ93473.1 - 0.047 13.8 2.9 0.55 10.3 0.3 3.0 2 1 0 2 2 2 0 GWT1 DUF2157 PF09925.9 KFQ93473.1 - 0.34 10.7 5.7 48 3.7 6.1 3.0 2 2 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF2207 PF09972.9 KFQ93473.1 - 1.2 7.8 8.2 14 4.3 0.0 3.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) SPICE PF15678.5 KFQ93474.1 - 8.9e-165 549.0 28.3 8.9e-165 549.0 28.3 1.8 2 1 0 2 2 2 1 Centriole duplication and mitotic chromosome congression Filamin PF00630.19 KFQ93475.1 - 4.1e-20 72.5 0.1 6.7e-20 71.8 0.1 1.4 1 0 0 1 1 1 1 Filamin/ABP280 repeat zf-B_box PF00643.24 KFQ93475.1 - 3.1e-11 43.2 3.2 3.1e-11 43.2 3.2 4.0 4 0 0 4 4 4 2 B-box zinc finger Laminin_II PF06009.12 KFQ93475.1 - 0.013 15.5 0.7 0.024 14.6 0.7 1.3 1 0 0 1 1 1 0 Laminin Domain II Y_Y_Y PF07495.13 KFQ93475.1 - 0.077 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Y_Y_Y domain V-set PF07686.17 KFQ93476.1 - 1.7e-11 44.3 0.1 8.2e-09 35.6 0.0 3.3 3 1 0 3 3 3 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFQ93476.1 - 4.7e-10 39.9 0.1 0.00023 21.7 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFQ93476.1 - 9.1e-07 28.9 0.4 0.0037 17.3 0.0 2.9 2 2 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFQ93476.1 - 2.6e-06 27.5 0.8 0.00017 21.7 0.0 3.0 2 2 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFQ93476.1 - 0.00048 20.4 0.7 1.2 9.5 0.4 2.7 1 1 0 2 2 2 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFQ93476.1 - 0.0018 18.3 0.0 0.0054 16.8 0.0 1.7 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFQ93476.1 - 0.015 14.9 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain EpuA PF11772.8 KFQ93476.1 - 0.07 12.8 1.5 0.13 12.0 1.5 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Pilin_N PF07790.11 KFQ93476.1 - 0.18 12.8 1.0 0.68 10.9 1.0 2.0 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal CTC1 PF15489.6 KFQ93477.1 - 4e-52 177.0 1.1 4.4e-52 176.9 1.1 1.0 1 0 0 1 1 1 1 CST, telomere maintenance, complex subunit CTC1 Death PF00531.22 KFQ93478.1 - 1.2e-18 67.1 0.1 1.9e-18 66.4 0.1 1.4 1 0 0 1 1 1 1 Death domain TNFR_c6 PF00020.18 KFQ93478.1 - 9.3e-16 58.0 55.8 2.7e-08 34.1 10.9 5.0 5 1 1 6 6 6 4 TNFR/NGFR cysteine-rich region NinF PF05810.12 KFQ93478.1 - 0.03 14.2 0.9 0.03 14.2 0.9 2.7 2 1 0 2 2 2 0 NinF protein DUF1391 PF07151.12 KFQ93478.1 - 0.15 11.9 0.9 0.38 10.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1391) Methyltransf_10 PF05971.12 KFQ93479.1 - 5.1e-114 380.6 0.0 1.1e-113 379.5 0.0 1.5 2 0 0 2 2 2 1 RNA methyltransferase MTS PF05175.14 KFQ93479.1 - 1.8e-05 24.4 0.0 3.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KFQ93479.1 - 0.00032 20.2 0.4 0.00056 19.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MANEC PF07502.14 KFQ93479.1 - 0.0081 16.4 0.9 0.019 15.2 0.3 1.9 2 0 0 2 2 2 1 MANEC domain TFIIE_alpha PF02002.17 KFQ93480.1 - 8.5e-36 122.0 0.6 1.5e-35 121.2 0.6 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 KFQ93480.1 - 1.8e-30 105.0 5.5 5.9e-30 103.4 5.5 1.9 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.12 KFQ93480.1 - 9.3e-12 44.3 1.0 1.8e-11 43.3 1.0 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 KFQ93480.1 - 0.051 13.5 0.1 0.093 12.7 0.1 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-Sec23_Sec24 PF04810.15 KFQ93480.1 - 0.13 12.3 0.4 11 6.2 0.1 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger PyrI_C PF02748.15 KFQ93480.1 - 0.37 10.7 1.6 1.3 9.0 1.8 1.9 1 1 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_4 PF13894.6 KFQ93480.1 - 0.99 10.4 3.0 5.9 8.0 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Roc PF08477.13 KFQ93481.1 - 5.6e-11 42.7 0.0 3e-10 40.4 0.0 1.9 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFQ93481.1 - 6.5e-09 35.6 0.0 2.4e-08 33.8 0.0 1.8 1 1 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KFQ93481.1 - 0.0021 18.1 0.0 0.0029 17.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KFQ93481.1 - 0.14 11.6 0.1 0.48 9.9 0.1 1.9 1 1 0 1 1 1 0 ADP-ribosylation factor family HgmA PF04209.13 KFQ93482.1 - 1.6e-222 738.7 0.0 1.8e-222 738.6 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase NDUF_B4 PF07225.12 KFQ93483.1 - 2.4e-30 105.0 0.0 2.6e-30 104.9 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) LRR_4 PF12799.7 KFQ93484.1 - 3.8e-16 58.9 18.8 1.1e-07 32.0 0.1 3.6 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFQ93484.1 - 2.6e-15 55.9 8.9 1.5e-11 43.9 6.2 2.9 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 KFQ93484.1 - 0.00014 21.9 13.6 1.3 9.9 0.0 5.7 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_9 PF14580.6 KFQ93484.1 - 0.0002 20.9 0.6 0.0004 19.9 0.5 1.5 1 1 0 1 1 1 1 Leucine-rich repeat 7tm_3 PF00003.22 KFQ93485.1 - 9.2e-40 136.8 18.2 1.2e-39 136.4 18.2 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Creatinase_N PF01321.18 KFQ93485.1 - 0.14 12.8 0.0 0.35 11.5 0.0 1.6 1 0 0 1 1 1 0 Creatinase/Prolidase N-terminal domain Pkinase PF00069.25 KFQ93486.1 - 2.8e-69 233.4 0.0 3.3e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ93486.1 - 2e-24 86.3 0.0 2.4e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ93486.1 - 3.7e-05 23.2 0.0 0.00032 20.1 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KFQ93486.1 - 0.0047 16.9 0.1 0.014 15.4 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFQ93486.1 - 0.02 14.3 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 KFQ93486.1 - 0.065 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Choline_kinase PF01633.20 KFQ93486.1 - 0.18 11.4 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase CFAP91 PF14738.6 KFQ93487.1 - 2.4e-65 219.3 8.6 2.4e-65 219.3 8.6 3.9 2 1 1 3 3 3 1 Cilia- and flagella-associated protein 91 DUF5624 PF18538.1 KFQ93487.1 - 0.017 15.2 1.9 0.046 13.8 1.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) DUF5607 PF18355.1 KFQ93487.1 - 0.059 13.8 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5607) Popeye PF04831.13 KFQ93488.1 - 1.2e-49 168.1 0.1 1.4e-49 167.9 0.1 1.1 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.29 KFQ93488.1 - 0.0029 17.7 0.0 0.0056 16.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain CAP_N PF01213.19 KFQ93488.1 - 0.43 10.0 8.2 0.61 9.5 8.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Lipase PF00151.19 KFQ93489.1 - 7.7e-99 331.2 0.0 9.2e-99 330.9 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 KFQ93489.1 - 0.0013 19.4 2.3 0.0018 18.9 2.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ig_3 PF13927.6 KFQ93490.1 - 4.3e-09 36.9 0.2 0.0031 18.1 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFQ93490.1 - 1.1e-06 28.7 0.6 0.0029 17.8 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFQ93490.1 - 1.4e-05 25.1 0.1 0.006 16.6 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 KFQ93490.1 - 1.8e-05 24.9 0.1 0.0011 19.1 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KFQ93490.1 - 0.00093 19.5 0.6 0.08 13.3 0.0 2.5 1 1 1 2 2 2 1 Immunoglobulin domain Ig_5 PF16681.5 KFQ93490.1 - 0.0025 18.2 0.6 0.11 12.9 0.1 2.3 2 0 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Receptor_2B4 PF11465.8 KFQ93490.1 - 0.0047 17.1 0.2 0.018 15.3 0.0 1.9 2 0 0 2 2 2 1 Natural killer cell receptor 2B4 MBG_2 PF18676.1 KFQ93490.1 - 0.011 16.3 0.4 0.023 15.3 0.4 1.5 1 0 0 1 1 1 0 MBG domain (YGX type) Ig_4 PF16680.5 KFQ93490.1 - 0.12 12.7 0.7 1.3 9.3 0.1 2.2 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain Cation_ATPase_C PF00689.21 KFQ93491.1 - 1.7e-44 151.7 0.3 1.7e-44 151.7 0.3 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KFQ93491.1 - 5.1e-44 149.9 0.6 5.1e-44 149.9 0.6 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KFQ93491.1 - 2.8e-24 85.0 0.0 6.4e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFQ93491.1 - 2.1e-18 67.4 0.3 4.1e-09 37.0 0.1 3.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFQ93491.1 - 4.8e-18 64.6 0.0 9.1e-18 63.7 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFQ93491.1 - 7.3e-06 25.9 1.2 0.00084 19.2 0.5 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Mab-21 PF03281.14 KFQ93492.1 - 3.7e-83 279.2 5.2 5e-83 278.8 5.2 1.2 1 0 0 1 1 1 1 Mab-21 protein MFS_1 PF07690.16 KFQ93493.1 - 2.1e-30 105.8 50.4 3.8e-24 85.3 31.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFQ93493.1 - 6.7e-29 101.0 14.8 9.5e-29 100.5 14.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Calsequestrin PF01216.17 KFQ93494.1 - 5.5e-214 710.3 43.8 2.2e-213 708.4 43.8 1.8 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_6 PF13848.6 KFQ93494.1 - 5.2e-21 75.4 5.1 1.8e-19 70.4 2.9 2.3 2 1 0 2 2 2 2 Thioredoxin-like domain SDA1 PF05285.12 KFQ93494.1 - 0.038 13.4 14.7 0.056 12.9 14.7 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KFQ93494.1 - 7.1 5.8 11.4 10 5.4 11.4 1.3 1 0 0 1 1 1 0 BUD22 Strabismus PF06638.11 KFQ93495.1 - 8.9e-255 846.0 0.1 1.1e-254 845.8 0.1 1.0 1 0 0 1 1 1 1 Strabismus protein CDT1_C PF16679.5 KFQ93495.1 - 0.043 14.3 1.7 0.096 13.1 1.6 1.6 1 1 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain SNF2_N PF00176.23 KFQ93496.1 - 9.4e-57 192.3 0.3 3.2e-56 190.6 0.3 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFQ93496.1 - 2.5e-15 56.8 0.0 2.2e-14 53.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFQ93496.1 - 1e-10 41.9 0.1 2.9e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFQ93496.1 - 1.2e-06 28.4 0.0 2.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KFQ93496.1 - 0.0012 18.0 0.2 0.0051 16.0 0.0 2.1 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.6 KFQ93496.1 - 0.0065 16.7 1.1 0.059 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain TT_ORF2 PF02957.15 KFQ93496.1 - 0.022 15.7 2.5 0.054 14.4 2.5 1.6 1 0 0 1 1 1 0 TT viral ORF2 Amidase PF01425.21 KFQ93497.1 - 3.8e-88 296.4 0.0 4.2e-87 293.0 0.0 1.9 1 1 0 1 1 1 1 Amidase UPF0052 PF01933.18 KFQ93497.1 - 0.19 10.9 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 Glyco_transf_7N PF13733.6 KFQ93498.1 - 2.4e-58 195.5 0.1 3.7e-58 194.9 0.1 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 KFQ93498.1 - 5.5e-28 96.4 0.6 1.4e-27 95.1 0.6 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Phycoerythr_ab PF02972.14 KFQ93498.1 - 0.1 12.4 0.0 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 Phycoerythrin, alpha/beta chain Glyco_transf_43 PF03360.16 KFQ93499.1 - 2.9e-72 242.8 0.0 3.4e-72 242.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 RhoGAP PF00620.27 KFQ93500.1 - 6.6e-32 110.4 0.4 1.6e-31 109.2 0.4 1.6 1 0 0 1 1 1 1 RhoGAP domain Tetraspanin PF00335.20 KFQ93501.1 - 4.8e-25 88.6 5.0 6.4e-25 88.2 5.0 1.1 1 0 0 1 1 1 1 Tetraspanin family YrvL PF14184.6 KFQ93501.1 - 0.0071 16.4 1.1 0.0071 16.4 1.1 1.8 2 0 0 2 2 2 1 Regulatory protein YrvL RasGEF_N PF00618.20 KFQ93501.1 - 0.024 14.9 0.0 0.041 14.1 0.0 1.3 1 0 0 1 1 1 0 RasGEF N-terminal motif Peptidase_M61 PF05299.12 KFQ93501.1 - 0.1 13.0 0.1 0.17 12.3 0.1 1.2 1 0 0 1 1 1 0 M61 glycyl aminopeptidase DUF5582 PF17819.1 KFQ93502.1 - 6.1e-27 94.9 0.1 8.5e-27 94.4 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5582) DUF5586 PF17824.1 KFQ93502.1 - 0.002 17.3 0.1 0.0029 16.8 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5586) COesterase PF00135.28 KFQ93503.1 - 3.4e-86 290.2 0.1 3.7e-86 290.0 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFQ93503.1 - 1e-07 32.1 4.7 1.9e-07 31.2 4.7 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold PDZ PF00595.24 KFQ93505.1 - 5.1e-33 113.3 4.8 2.4e-13 50.2 0.1 3.4 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 KFQ93505.1 - 3.1e-16 58.9 1.6 9.9e-07 28.5 0.0 3.4 3 0 0 3 3 3 2 PDZ domain Guanylate_kin PF00625.21 KFQ93505.1 - 1.3e-12 47.8 0.1 2.7e-12 46.7 0.1 1.5 1 0 0 1 1 1 1 Guanylate kinase PDZ_2 PF13180.6 KFQ93505.1 - 4e-10 39.9 0.4 0.00046 20.5 0.0 3.4 3 0 0 3 3 3 2 PDZ domain SH3_2 PF07653.17 KFQ93505.1 - 1.3e-08 34.4 0.5 1.4e-07 31.1 0.0 3.0 4 0 0 4 4 4 1 Variant SH3 domain SH3_1 PF00018.28 KFQ93505.1 - 0.00021 20.8 0.0 0.0032 17.0 0.0 3.0 2 0 0 2 2 2 1 SH3 domain Frataxin_Cyay PF01491.16 KFQ93506.1 - 6.7e-37 125.9 0.0 8e-37 125.6 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain ORF_12_N PF18042.1 KFQ93506.1 - 0.14 12.6 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 ORF 12 gene product N-terminal PIP5K PF01504.18 KFQ93507.1 - 1.3e-92 309.9 0.1 1.7e-92 309.5 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Yae1_N PF09811.9 KFQ93508.1 - 3.1e-09 36.4 38.8 12 5.7 1.4 4.3 2 1 0 2 2 2 2 Essential protein Yae1, N terminal Flavokinase PF01687.17 KFQ93509.1 - 4.1e-24 85.0 0.0 4.6e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase zf-CHC2 PF01807.20 KFQ93509.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 CHC2 zinc finger DUF3248 PF11609.8 KFQ93509.1 - 0.065 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) VPS28 PF03997.12 KFQ93510.1 - 1.9e-43 148.4 0.2 2.1e-43 148.2 0.2 1.0 1 0 0 1 1 1 1 VPS28 protein RIG-I_C PF18119.1 KFQ93510.1 - 0.0018 18.3 0.1 0.0026 17.8 0.1 1.3 1 0 0 1 1 1 1 RIG-I receptor C-terminal domain DUF4477 PF14780.6 KFQ93510.1 - 0.088 12.4 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) CEP209_CC5 PF16574.5 KFQ93510.1 - 0.091 12.9 0.0 0.2 11.8 0.0 1.6 1 1 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 FancD2 PF14631.6 KFQ93512.1 - 0 2426.8 18.7 0 2426.5 18.7 1.0 1 0 0 1 1 1 1 Fanconi anaemia protein FancD2 nuclease FANCI_S2 PF14676.6 KFQ93512.1 - 5.5e-05 23.5 0.3 5.5e-05 23.5 0.3 4.4 4 1 1 5 5 5 1 FANCI solenoid 2 EMC3_TMCO1 PF01956.16 KFQ93513.1 - 2.7e-36 124.9 4.7 4.6e-36 124.1 0.4 2.1 2 0 0 2 2 2 2 Integral membrane protein EMC3/TMCO1-like GSHPx PF00255.19 KFQ93514.1 - 1.2e-26 92.4 0.3 1.5e-26 92.1 0.3 1.1 1 0 0 1 1 1 1 Glutathione peroxidase GyrI-like PF06445.15 KFQ93515.1 - 0.01 16.2 0.1 0.025 14.9 0.0 1.7 2 0 0 2 2 2 0 GyrI-like small molecule binding domain WD40 PF00400.32 KFQ93516.1 - 2.1e-12 47.3 2.0 0.013 16.4 0.0 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat Troponin PF00992.20 KFQ93516.1 - 0.0087 16.4 1.6 0.013 15.8 1.6 1.2 1 0 0 1 1 1 1 Troponin HEAT PF02985.22 KFQ93517.1 - 0.27 11.6 1.5 3.8 8.0 0.2 3.2 4 0 0 4 4 4 0 HEAT repeat IFRD PF05004.13 KFQ93518.1 - 1.4e-20 73.6 0.1 1.5e-20 73.5 0.1 1.0 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) DUF3730 PF12530.8 KFQ93518.1 - 0.022 14.3 0.0 0.024 14.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) OAS1_C PF10421.9 KFQ93519.1 - 1.9e-69 232.8 0.0 3.7e-69 231.9 0.0 1.4 1 0 0 1 1 1 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus ubiquitin PF00240.23 KFQ93519.1 - 7.6e-31 105.7 0.4 6.5e-21 73.9 0.1 3.4 2 1 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 KFQ93519.1 - 4.7e-10 39.2 0.1 1.4e-07 31.3 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFQ93519.1 - 7.8e-09 35.9 0.1 0.0066 16.9 0.0 2.7 1 1 0 2 2 2 2 Ubiquitin-like domain NTP_transf_2 PF01909.23 KFQ93519.1 - 4.6e-06 26.8 0.0 1.3e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain SMODS PF18144.1 KFQ93519.1 - 0.00011 22.4 0.0 0.00024 21.3 0.0 1.6 1 0 0 1 1 1 1 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain Ubiquitin_4 PF18036.1 KFQ93519.1 - 0.0019 18.2 0.0 0.33 11.0 0.0 3.0 3 0 0 3 3 3 1 Ubiquitin-like domain UN_NPL4 PF11543.8 KFQ93519.1 - 0.0096 16.4 0.0 0.3 11.6 0.0 2.4 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 Rad60-SLD_2 PF13881.6 KFQ93519.1 - 0.018 15.2 0.4 0.29 11.2 0.2 2.4 1 1 1 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Sema PF01403.19 KFQ93520.1 - 2.8e-157 523.9 0.0 3.3e-157 523.7 0.0 1.0 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 KFQ93520.1 - 0.0079 16.7 5.8 0.0079 16.7 5.8 2.4 3 0 0 3 3 3 1 Plexin repeat Aa_trans PF01490.18 KFQ93521.1 - 1.8e-07 30.2 1.8 2.1e-07 30.0 1.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein G-alpha PF00503.20 KFQ93522.1 - 2e-117 392.3 4.9 2.3e-117 392.1 4.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFQ93522.1 - 1.1e-13 51.1 0.4 9.1e-13 48.0 0.1 2.5 3 0 0 3 3 3 1 ADP-ribosylation factor family DUF261 PF03196.13 KFQ93522.1 - 0.03 14.4 0.8 3.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF261 Sema PF01403.19 KFQ93523.1 - 9e-147 489.3 0.0 1e-146 489.1 0.0 1.0 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 KFQ93523.1 - 0.0023 18.4 7.5 0.0069 16.9 7.5 1.9 1 0 0 1 1 1 1 Plexin repeat OCRE PF17780.1 KFQ93524.1 - 3.4e-19 68.6 18.4 3.4e-19 68.6 18.4 2.2 2 0 0 2 2 2 1 OCRE domain G-patch PF01585.23 KFQ93524.1 - 4.2e-19 68.2 3.1 7.5e-19 67.4 3.1 1.5 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KFQ93524.1 - 3e-15 55.8 0.0 5.2e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 KFQ93524.1 - 7e-11 41.2 3.5 1.2e-10 40.4 3.5 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.7 KFQ93524.1 - 4.7e-08 33.0 1.4 4.7e-08 33.0 1.4 2.5 3 0 0 3 3 3 1 G-patch domain GSIII_N PF12437.8 KFQ93524.1 - 0.0018 18.0 0.9 0.0042 16.8 0.9 1.5 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal zf-C2HE PF16278.5 KFQ93524.1 - 0.093 13.2 4.6 0.46 11.0 1.0 2.8 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger RED_N PF07808.13 KFQ93524.1 - 0.88 9.1 12.1 0.062 12.9 1.7 2.5 2 0 0 2 2 2 0 RED-like protein N-terminal region LegC3_N PF18654.1 KFQ93524.1 - 2.1 7.5 11.7 0.15 11.3 1.5 2.3 2 0 0 2 2 2 0 LegC3 N-terminal coiled-coil domain KH_1 PF00013.29 KFQ93525.1 - 7.7e-51 169.8 11.8 3.6e-18 65.1 0.3 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KFQ93525.1 - 1.3e-14 53.7 4.2 0.00011 21.9 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KFQ93525.1 - 3.1e-08 33.4 1.1 0.011 15.6 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KFQ93525.1 - 8.7e-05 22.5 5.0 2.9 8.0 0.1 3.5 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 KFQ93525.1 - 0.0037 17.2 0.1 0.1 12.6 0.0 2.8 3 0 0 3 3 3 1 KH-like RNA-binding domain Abhydrolase_1 PF00561.20 KFQ93526.1 - 8.1e-10 38.8 0.0 0.00067 19.4 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFQ93526.1 - 5.6e-07 30.4 1.0 0.001 19.7 0.4 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFQ93526.1 - 9.4e-05 21.8 0.1 0.19 10.9 0.0 2.5 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 KFQ93526.1 - 0.0033 17.0 0.0 0.02 14.5 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KFQ93526.1 - 0.1 12.2 0.0 0.98 8.9 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KFQ93527.1 - 5.5e-09 37.0 5.3 0.00022 21.9 0.4 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFQ93527.1 - 1.4e-07 31.4 0.0 0.00011 22.0 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFQ93527.1 - 0.00018 20.9 0.1 0.12 11.6 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 KFQ93527.1 - 0.013 15.1 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Peptidase_M20 PF01546.28 KFQ93528.1 - 3.3e-36 124.9 0.0 4.4e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFQ93528.1 - 1.8e-13 50.3 0.0 3.1e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KFQ93528.1 - 8e-06 25.7 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Sema PF01403.19 KFQ93529.1 - 6.8e-144 479.8 0.0 8.7e-144 479.4 0.0 1.1 1 0 0 1 1 1 1 Sema domain V-set PF07686.17 KFQ93529.1 - 0.00014 22.0 0.2 0.0066 16.6 0.2 2.4 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFQ93529.1 - 0.00023 21.3 0.0 0.00047 20.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFQ93529.1 - 0.001 19.6 0.0 0.0027 18.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 KFQ93529.1 - 0.0012 18.4 0.0 0.0026 17.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain PSI PF01437.25 KFQ93529.1 - 0.0013 19.2 8.4 0.0029 18.1 8.4 1.6 1 0 0 1 1 1 1 Plexin repeat I-set PF07679.16 KFQ93529.1 - 0.0017 18.4 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFQ93529.1 - 0.13 12.6 0.0 1.1 9.7 0.0 2.5 3 0 0 3 3 3 0 Immunoglobulin domain Peptidase_C12 PF01088.21 KFQ93530.1 - 2.2e-63 213.8 0.0 4.8e-63 212.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KFQ93530.1 - 6.8e-17 61.1 0.1 1.7e-16 59.8 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Nucleo_P87 PF07267.11 KFQ93530.1 - 1.2 7.9 9.4 2.2 7.0 9.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HAUS-augmin3 PF14932.6 KFQ93531.1 - 2.8e-87 292.6 7.7 2.8e-87 292.6 7.7 4.0 3 1 0 3 3 3 1 HAUS augmin-like complex subunit 3 Coat_F PF07875.12 KFQ93531.1 - 0.06 13.6 2.5 0.2 11.9 0.2 3.0 3 0 0 3 3 3 0 Coat F domain DUF2129 PF09902.9 KFQ93531.1 - 0.077 13.1 0.2 0.32 11.1 0.2 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2129) PSP1 PF04468.12 KFQ93531.1 - 3.5 8.0 7.3 0.6 10.4 0.2 3.1 3 1 0 3 3 3 0 PSP1 C-terminal conserved region Cofilin_ADF PF00241.20 KFQ93532.1 - 1.2e-41 141.2 0.5 3.1e-22 78.7 0.5 2.7 3 0 0 3 3 3 2 Cofilin/tropomyosin-type actin-binding protein WD40 PF00400.32 KFQ93532.1 - 4.3e-17 62.2 0.7 3.7e-05 24.4 0.0 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ93532.1 - 5.6e-10 39.4 0.0 0.00081 19.6 0.0 3.8 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain MinC_C PF03775.16 KFQ93532.1 - 0.21 11.6 0.0 0.62 10.1 0.0 1.7 1 0 0 1 1 1 0 Septum formation inhibitor MinC, C-terminal domain PD40 PF07676.12 KFQ93532.1 - 1.1 9.3 5.0 15 5.6 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PP2C PF00481.21 KFQ93533.1 - 1.8e-33 116.3 0.0 3.6e-15 56.3 0.0 3.0 2 1 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 KFQ93533.1 - 4.9e-05 23.3 0.0 0.075 12.9 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KFQ93533.1 - 0.053 13.2 0.0 0.88 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein phosphatase 2C Aminotran_1_2 PF00155.21 KFQ93534.1 - 6.9e-78 262.4 0.0 8.6e-78 262.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Preseq_ALAS PF09029.10 KFQ93534.1 - 1.1e-18 67.7 2.2 2.4e-18 66.7 2.2 1.6 1 0 0 1 1 1 1 5-aminolevulinate synthase presequence Cys_Met_Meta_PP PF01053.20 KFQ93534.1 - 1.7e-07 30.2 0.0 9.2e-07 27.7 0.0 1.9 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KFQ93534.1 - 1.2e-05 24.5 0.0 2.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFQ93534.1 - 0.00061 19.2 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KFQ93534.1 - 0.0081 15.5 0.3 0.028 13.7 0.3 1.8 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family WD40 PF00400.32 KFQ93535.1 - 1.7e-65 215.4 20.6 1.5e-09 38.3 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ93535.1 - 9.8e-24 83.5 0.2 0.00045 20.5 0.0 6.9 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFQ93535.1 - 1.1e-11 44.3 2.9 0.0075 15.3 0.1 5.0 1 1 4 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFQ93535.1 - 8.2e-10 38.9 0.1 9.1e-06 25.7 0.0 2.6 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KFQ93535.1 - 0.00045 18.9 0.1 3 6.3 0.0 3.0 1 1 2 3 3 3 3 Cytochrome D1 heme domain Proteasome_A_N PF10584.9 KFQ93535.1 - 0.0022 17.6 0.4 1 9.1 0.0 3.5 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature Syntaxin-6_N PF09177.11 KFQ93535.1 - 0.0058 17.2 1.2 0.011 16.3 1.2 1.4 1 0 0 1 1 1 1 Syntaxin 6, N-terminal Nup160 PF11715.8 KFQ93535.1 - 0.0099 14.6 6.7 4.7 5.7 0.0 4.3 2 2 2 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.12 KFQ93535.1 - 0.025 14.5 0.2 2.2 8.3 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 KFQ93535.1 - 0.057 12.2 0.4 0.34 9.6 0.3 2.1 2 1 0 2 2 2 0 Nup133 N terminal like WD40_like PF17005.5 KFQ93535.1 - 0.068 12.5 0.0 27 4.0 0.0 3.7 2 2 4 6 6 6 0 WD40-like domain DSPc PF00782.20 KFQ93536.1 - 3.8e-43 146.5 0.0 5.3e-43 146.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 KFQ93536.1 - 0.00018 22.0 0.0 0.00035 21.1 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase PF00102.27 KFQ93536.1 - 0.00049 19.7 0.0 0.00077 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KFQ93536.1 - 0.0071 16.6 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 KFQ93536.1 - 0.021 14.9 0.0 0.051 13.7 0.0 1.6 2 0 0 2 2 2 0 Inositol hexakisphosphate HSF_DNA-bind PF00447.17 KFQ93537.1 - 6.4e-20 71.6 0.1 7.6e-20 71.3 0.1 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding EF-hand_7 PF13499.6 KFQ93538.1 - 1e-27 96.4 9.8 1.7e-16 60.4 6.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFQ93538.1 - 1.1e-27 95.7 15.6 3.9e-15 55.4 0.4 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KFQ93538.1 - 8.6e-26 87.5 24.4 3.3e-08 32.5 1.0 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 KFQ93538.1 - 1.3e-20 71.5 15.9 3.2e-07 29.7 2.1 5.0 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFQ93538.1 - 2.9e-15 55.0 20.4 1.1e-06 27.8 0.3 5.0 4 1 1 5 5 5 3 EF hand EF-hand_9 PF14658.6 KFQ93538.1 - 6e-13 48.9 1.1 3.7e-06 27.2 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KFQ93538.1 - 1e-06 28.6 7.1 0.012 15.5 0.1 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFQ93538.1 - 4.8e-05 23.6 1.7 0.0013 19.1 0.5 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 KFQ93538.1 - 0.0021 18.0 0.1 1.2 9.1 0.0 2.3 1 1 0 2 2 2 2 Tellurite resistance protein TerB DUF1707 PF08044.11 KFQ93538.1 - 0.0041 17.1 0.5 1.8 8.7 0.1 3.3 3 1 1 4 4 4 1 Domain of unknown function (DUF1707) UPF0154 PF03672.13 KFQ93538.1 - 0.0069 16.4 0.0 2.1 8.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) DUF5580 PF17743.1 KFQ93538.1 - 0.014 13.9 0.0 0.017 13.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_10 PF14788.6 KFQ93538.1 - 0.029 14.2 4.1 0.097 12.5 0.8 2.8 2 1 1 3 3 3 0 EF hand DUF1456 PF07308.13 KFQ93538.1 - 0.03 14.6 2.3 2.5 8.5 0.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1456) EMG1 PF03587.14 KFQ93538.1 - 0.074 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 EMG1/NEP1 methyltransferase SapB_1 PF05184.15 KFQ93538.1 - 0.14 12.2 0.3 9.6 6.3 0.0 3.0 3 0 0 3 3 3 0 Saposin-like type B, region 1 Syntaxin PF00804.25 KFQ93538.1 - 0.15 11.7 2.3 1.7 8.3 0.4 2.3 2 0 0 2 2 2 0 Syntaxin RNA_pol_Rpb4 PF03874.16 KFQ93538.1 - 0.91 9.9 3.9 22 5.4 0.1 2.5 3 0 0 3 3 3 0 RNA polymerase Rpb4 PX PF00787.24 KFQ93539.1 - 2.5e-19 69.3 2.4 3e-19 69.1 2.4 1.0 1 0 0 1 1 1 1 PX domain EBV-NA3 PF05009.12 KFQ93539.1 - 0.12 11.9 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) 5_nucleotid PF05761.14 KFQ93541.1 - 1e-153 512.6 4.7 1.2e-153 512.4 4.7 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.6 KFQ93541.1 - 0.0031 17.6 1.1 0.04 14.0 1.7 2.6 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase UPF0640 PF15114.6 KFQ93542.1 - 2.7e-35 119.9 2.6 3e-35 119.8 2.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0640 GN3L_Grn1 PF08701.11 KFQ93543.1 - 3.7e-20 71.8 28.3 3.7e-20 71.8 28.3 3.8 2 2 2 4 4 4 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KFQ93543.1 - 5.4e-13 49.0 0.1 8.5e-11 41.9 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFQ93543.1 - 1.7e-06 27.7 0.1 0.0001 21.9 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Hus1 PF04005.12 KFQ93543.1 - 0.00088 18.5 0.2 0.00088 18.5 0.2 1.8 2 0 0 2 2 2 1 Hus1-like protein RsgA_GTPase PF03193.16 KFQ93543.1 - 0.024 14.6 9.1 0.26 11.2 0.4 3.1 2 1 1 3 3 3 0 RsgA GTPase DUF2291 PF10054.9 KFQ93543.1 - 0.031 14.0 3.2 0.069 12.9 3.2 1.5 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2291) Dynamin_N PF00350.23 KFQ93543.1 - 0.036 14.1 0.0 0.036 14.1 0.0 3.7 3 1 0 3 3 3 0 Dynamin family MeaB PF03308.16 KFQ93543.1 - 0.053 12.5 0.0 0.053 12.5 0.0 2.1 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Glyco_transf_8 PF01501.20 KFQ93544.1 - 4.6e-58 196.8 0.1 5.4e-58 196.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KFQ93544.1 - 0.0042 16.5 0.1 0.0076 15.7 0.1 1.5 1 1 0 1 1 1 1 Glucosyltransferase 24 Glyco_tranf_2_3 PF13641.6 KFQ93544.1 - 0.015 15.2 0.3 5.7 6.8 0.1 2.7 3 1 0 3 3 3 0 Glycosyltransferase like family 2 Synapsin_N PF10581.9 KFQ93544.1 - 0.15 12.0 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 Synapsin N-terminal SPC12 PF06645.13 KFQ93545.1 - 1.6e-31 108.2 1.2 1.8e-31 108.1 1.2 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MFS_1 PF07690.16 KFQ93545.1 - 0.0011 18.0 0.0 0.0011 17.9 0.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3169 PF11368.8 KFQ93545.1 - 0.028 13.9 0.5 0.035 13.6 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) TMEM208_SND2 PF05620.11 KFQ93545.1 - 0.12 12.1 0.1 0.14 12.0 0.1 1.1 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 LapA_dom PF06305.11 KFQ93545.1 - 1.7 8.5 3.6 13 5.7 0.8 2.1 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain ITI_HC_C PF06668.12 KFQ93546.1 - 2.7e-71 239.1 0.1 4.9e-71 238.3 0.1 1.4 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus VIT PF08487.10 KFQ93546.1 - 8.6e-32 109.7 3.2 2e-31 108.5 3.2 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 KFQ93546.1 - 3.3e-20 73.0 0.0 6.6e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFQ93546.1 - 8.8e-14 51.7 0.0 1.4e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFQ93546.1 - 3.4e-11 43.7 0.0 8.6e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 KFQ93546.1 - 0.00089 19.4 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_CoxE PF05762.14 KFQ93546.1 - 0.023 14.1 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein SRP14 PF02290.15 KFQ93546.1 - 0.13 12.6 0.2 0.34 11.3 0.2 1.7 1 0 0 1 1 1 0 Signal recognition particle 14kD protein Mustang PF15682.5 KFQ93547.1 - 3.2e-41 139.3 3.0 3.5e-41 139.2 3.0 1.0 1 0 0 1 1 1 1 Musculoskeletal, temporally activated-embryonic nuclear protein 1 Fer4_13 PF13370.6 KFQ93547.1 - 0.12 12.9 0.0 0.23 12.0 0.0 1.5 1 1 0 1 1 1 0 4Fe-4S single cluster domain of Ferredoxin I STIMATE PF12400.8 KFQ93548.1 - 1.3e-33 116.2 9.8 1.5e-33 116.0 9.0 1.4 2 0 0 2 2 2 1 STIMATE family DUF996 PF06195.13 KFQ93548.1 - 0.53 10.6 9.1 0.69 10.2 3.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF996) Sm_multidrug_ex PF06695.11 KFQ93548.1 - 1.9 9.2 6.7 36 5.0 0.0 3.1 2 1 1 3 3 3 0 Putative small multi-drug export protein WAPL PF07814.13 KFQ93549.1 - 0.058 12.2 0.0 0.058 12.2 0.0 1.0 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin Rft-1 PF04506.13 KFQ93550.1 - 2.9e-142 475.0 26.9 3.3e-142 474.8 26.9 1.0 1 0 0 1 1 1 1 Rft protein Phtf-FEM1B_bdg PF12129.8 KFQ93550.1 - 0.056 13.3 2.1 0.23 11.3 2.1 2.1 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor Sec62 PF03839.16 KFQ93550.1 - 6.3 6.2 9.8 0.38 10.2 3.9 1.9 2 0 0 2 2 2 0 Translocation protein Sec62 Pkinase PF00069.25 KFQ93551.1 - 5.6e-56 189.8 0.0 7.5e-55 186.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ93551.1 - 3.1e-32 111.9 0.0 5.2e-31 107.9 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KFQ93551.1 - 8.2e-32 108.9 20.4 3.7e-17 62.0 7.1 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KFQ93551.1 - 1.2e-08 35.5 1.7 2.3e-08 34.6 1.7 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain C1_2 PF03107.16 KFQ93551.1 - 3.7e-05 23.9 13.8 0.0013 19.0 3.1 2.5 2 0 0 2 2 2 2 C1 domain zf-RING-like PF08746.11 KFQ93551.1 - 0.00073 19.8 19.2 0.044 14.1 6.7 2.7 2 0 0 2 2 2 2 RING-like domain Zf_RING PF16744.5 KFQ93551.1 - 0.0029 17.7 9.3 0.003 17.7 1.5 2.5 2 0 0 2 2 2 1 KIAA1045 RING finger zf-RING_9 PF13901.6 KFQ93551.1 - 0.021 14.8 14.2 0.24 11.4 4.0 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon PHD PF00628.29 KFQ93551.1 - 0.024 14.5 18.3 0.093 12.6 3.5 2.6 2 0 0 2 2 2 0 PHD-finger DUF2318 PF10080.9 KFQ93551.1 - 0.043 13.9 10.8 0.042 14.0 1.5 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Haspin_kinase PF12330.8 KFQ93551.1 - 0.054 12.4 0.1 0.15 11.0 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Spore_YhaL PF14147.6 KFQ93551.1 - 0.12 12.1 0.1 0.5 10.1 0.1 2.1 2 0 0 2 2 2 0 Sporulation protein YhaL DZR PF12773.7 KFQ93551.1 - 0.16 12.1 12.6 0.47 10.5 2.7 2.7 2 0 0 2 2 2 0 Double zinc ribbon Prok-RING_1 PF14446.6 KFQ93551.1 - 0.24 11.4 13.0 1.8 8.6 3.0 3.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 CxC3 PF18804.1 KFQ93551.1 - 0.89 9.4 6.1 1.1 9.2 0.5 3.0 3 0 0 3 3 3 0 CxC3 like cysteine cluster associated with KDZ transposases PADR1 PF08063.12 KFQ93551.1 - 2.1 8.2 12.1 0.053 13.3 2.8 2.7 2 0 0 2 2 2 0 PADR1 (NUC008) domain FYVE_2 PF02318.16 KFQ93551.1 - 4.9 7.4 11.1 2.8 8.2 2.0 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger zf-ACC PF17848.1 KFQ93551.1 - 6.2 7.0 10.6 29 4.8 2.6 3.5 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain 6PF2K PF01591.18 KFQ93552.1 - 2.5e-102 340.9 1.5 3.2e-102 340.6 0.7 1.5 2 0 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KFQ93552.1 - 9.2e-43 146.2 0.0 1.3e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KFQ93552.1 - 4.8e-08 33.3 0.0 1.2e-07 32.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain Prefoldin PF02996.17 KFQ93552.1 - 0.00074 19.4 1.0 0.0012 18.7 0.0 1.9 2 0 0 2 2 2 1 Prefoldin subunit KTI12 PF08433.10 KFQ93552.1 - 0.0008 18.9 0.1 0.0015 18.1 0.1 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 KFQ93552.1 - 0.013 16.0 0.0 0.027 15.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain His_Phos_2 PF00328.22 KFQ93552.1 - 0.031 13.6 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Zeta_toxin PF06414.12 KFQ93552.1 - 0.073 12.3 0.0 0.23 10.7 0.0 2.0 1 1 0 1 1 1 0 Zeta toxin HSF_DNA-bind PF00447.17 KFQ93553.1 - 1.9e-21 76.5 0.1 2.2e-21 76.3 0.1 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding Glyco_hydro_56 PF01630.18 KFQ93554.1 - 2.5e-135 450.8 0.2 3e-135 450.5 0.2 1.0 1 0 0 1 1 1 1 Hyaluronidase EGF_2 PF07974.13 KFQ93554.1 - 0.012 15.9 9.7 0.34 11.3 0.9 2.4 2 0 0 2 2 2 0 EGF-like domain Glyco_hydro_56 PF01630.18 KFQ93555.1 - 1.1e-145 484.8 0.2 1.3e-145 484.6 0.2 1.0 1 0 0 1 1 1 1 Hyaluronidase EGF PF00008.27 KFQ93555.1 - 0.032 14.5 3.8 0.27 11.6 0.2 2.6 2 0 0 2 2 2 0 EGF-like domain EGF_2 PF07974.13 KFQ93555.1 - 0.27 11.6 12.9 1.5 9.3 4.2 2.6 2 0 0 2 2 2 0 EGF-like domain TUSC2 PF15000.6 KFQ93556.1 - 4.9e-33 113.7 0.1 5.4e-33 113.6 0.1 1.0 1 0 0 1 1 1 1 Tumour suppressor candidate 2 zf-MYND PF01753.18 KFQ93557.1 - 1.4e-09 37.8 19.6 1.4e-09 37.8 19.6 2.1 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.16 KFQ93557.1 - 1.1 9.2 8.2 2 8.4 8.2 1.4 1 0 0 1 1 1 0 HIT zinc finger NPR2 PF06218.11 KFQ93558.1 - 1e-77 261.8 7.1 2.6e-41 141.8 2.5 3.0 1 1 2 3 3 3 3 Nitrogen permease regulator 2 Cytochrom_B561 PF03188.16 KFQ93559.1 - 3.8e-37 127.5 11.5 5.4e-37 127.0 11.5 1.2 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF1751 PF08551.10 KFQ93560.1 - 1.2e-19 70.7 0.9 1.2e-19 70.7 0.9 1.9 2 1 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) VGCC_alpha2 PF08473.11 KFQ93561.1 - 1.4e-136 455.7 0.9 1.3e-132 442.7 0.2 2.0 2 0 0 2 2 2 2 Neuronal voltage-dependent calcium channel alpha 2acd VWA PF00092.28 KFQ93562.1 - 1.8e-09 38.1 0.0 2.2e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFQ93562.1 - 4.5e-05 23.4 0.0 5.8e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFQ93562.1 - 0.0081 16.8 0.0 0.032 14.9 0.0 1.8 1 1 1 2 2 2 1 von Willebrand factor type A domain CEP19 PF14933.6 KFQ93565.1 - 0.13 12.6 0.0 0.16 12.3 0.0 1.1 1 0 0 1 1 1 0 CEP19-like protein Gram_pos_anchor PF00746.21 KFQ93565.1 - 0.15 12.0 0.7 0.25 11.3 0.7 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif LapA_dom PF06305.11 KFQ93565.1 - 0.19 11.6 1.2 0.41 10.5 1.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain MTS PF05175.14 KFQ93566.1 - 3.1e-13 49.6 0.0 1.2e-12 47.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KFQ93566.1 - 2.3e-09 37.2 0.0 3.2e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFQ93566.1 - 7.1e-09 36.3 0.0 1.6e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KFQ93566.1 - 4.4e-08 33.0 0.0 8.9e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.13 KFQ93566.1 - 6.8e-08 32.3 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PrmC_N PF17827.1 KFQ93566.1 - 3.2e-07 30.8 0.0 6.3e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 PrmC N-terminal domain Methyltransf_4 PF02390.17 KFQ93566.1 - 5.1e-06 26.1 0.1 3.8e-05 23.2 0.0 2.4 3 1 1 4 4 4 1 Putative methyltransferase UPF0020 PF01170.18 KFQ93566.1 - 3e-05 23.8 0.1 0.0001 22.1 0.1 1.8 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 KFQ93566.1 - 7.9e-05 23.3 0.0 0.00015 22.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFQ93566.1 - 9.4e-05 23.0 0.0 0.00018 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KFQ93566.1 - 0.00039 21.4 0.0 0.00086 20.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KFQ93566.1 - 0.0013 18.7 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 KFQ93566.1 - 0.0028 17.3 0.0 0.0062 16.2 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_15 PF09445.10 KFQ93566.1 - 0.0055 16.3 0.0 0.014 14.9 0.0 1.6 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_23 PF13489.6 KFQ93566.1 - 0.0061 16.4 0.0 0.024 14.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 KFQ93566.1 - 0.011 15.5 0.0 0.048 13.4 0.0 1.9 2 0 0 2 2 2 0 DNA methylase Methyltransf_16 PF10294.9 KFQ93566.1 - 0.015 15.0 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_3 PF01596.17 KFQ93566.1 - 0.026 13.7 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_32 PF13679.6 KFQ93566.1 - 0.033 14.2 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KFQ93566.1 - 0.044 13.5 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14 PF08704.10 KFQ93566.1 - 0.095 12.4 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltrans_SAM PF10672.9 KFQ93566.1 - 0.11 11.7 0.0 0.26 10.4 0.0 1.6 2 0 0 2 2 2 0 S-adenosylmethionine-dependent methyltransferase PRMT5 PF05185.16 KFQ93566.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase DUF938 PF06080.12 KFQ93566.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) EcoRI_methylase PF13651.6 KFQ93566.1 - 0.13 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Adenine-specific methyltransferase EcoRI SH2 PF00017.24 KFQ93567.1 - 1.3e-13 50.8 0.0 2.3e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.16 KFQ93567.1 - 5.6e-12 45.8 0.6 1.7e-11 44.3 0.6 1.9 1 0 0 1 1 1 1 SOCS box SH2_2 PF14633.6 KFQ93567.1 - 0.19 11.1 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 SH2 domain Pkinase PF00069.25 KFQ93568.1 - 8.4e-69 231.9 0.0 1.4e-68 231.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ93568.1 - 3.2e-29 102.0 0.0 4.9e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFQ93568.1 - 2.3e-07 30.4 0.2 4.2e-07 29.5 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFQ93568.1 - 0.0041 15.9 0.0 0.011 14.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase VF530 PF09905.9 KFQ93568.1 - 0.048 13.8 0.0 0.41 10.8 0.0 2.3 2 0 0 2 2 2 0 DNA-binding protein VF530 PAXIP1_C PF15364.6 KFQ93568.1 - 0.061 13.6 0.7 0.33 11.3 0.2 2.4 3 0 0 3 3 3 0 PAXIP1-associated-protein-1 C term PTIP binding protein Choline_kinase PF01633.20 KFQ93568.1 - 0.087 12.4 0.0 0.35 10.4 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase CHGN PF05679.16 KFQ93570.1 - 2.5e-175 584.2 0.1 2.8e-175 584.0 0.1 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 KFQ93570.1 - 3.7e-10 39.3 0.1 9.1e-10 38.1 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KFQ93570.1 - 1.2e-06 28.3 0.0 8.4e-06 25.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KFQ93570.1 - 0.086 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 COX7C PF02935.16 KFQ93571.1 - 1.5e-16 60.4 0.4 1.6e-16 60.3 0.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc LapA_dom PF06305.11 KFQ93571.1 - 0.083 12.7 0.0 0.083 12.7 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Cbl_N3 PF02762.14 KFQ93572.1 - 3.6e-46 154.9 0.0 7.7e-46 153.9 0.0 1.6 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain Cbl_N PF02262.16 KFQ93572.1 - 1.1e-45 154.7 0.4 1.7e-45 154.0 0.4 1.4 1 0 0 1 1 1 1 CBL proto-oncogene N-terminal domain 1 Cbl_N2 PF02761.14 KFQ93572.1 - 1.3e-41 141.2 0.7 2.3e-41 140.4 0.7 1.5 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain Prok-RING_4 PF14447.6 KFQ93572.1 - 3.6e-13 49.2 9.1 6.4e-13 48.3 9.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFQ93572.1 - 5.1e-11 42.3 8.3 8.8e-11 41.5 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ93572.1 - 5.8e-09 35.7 7.9 1.1e-08 34.9 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ93572.1 - 1.6e-08 34.7 7.7 3.1e-08 33.8 7.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFQ93572.1 - 2.8e-05 23.9 8.1 5.1e-05 23.0 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFQ93572.1 - 0.00031 20.7 5.7 0.00085 19.3 5.2 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFQ93572.1 - 0.0034 17.3 10.7 0.0065 16.4 10.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFQ93572.1 - 0.026 14.8 7.4 0.048 14.0 7.4 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KFQ93572.1 - 0.029 14.5 8.3 0.068 13.3 8.3 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KFQ93572.1 - 0.032 14.0 10.7 0.041 13.7 9.8 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 KFQ93572.1 - 1.3 9.2 6.4 4.4 7.5 6.4 1.9 1 1 0 1 1 1 0 Zinc-binding RING-finger IL2 PF00715.17 KFQ93573.1 - 0.00012 22.0 2.0 0.00019 21.4 2.0 1.3 1 0 0 1 1 1 1 Interleukin 2 Leu_zip PF15294.6 KFQ93573.1 - 0.00048 19.7 12.4 0.00048 19.7 12.4 1.6 2 0 0 2 2 2 1 Leucine zipper Apolipoprotein PF01442.18 KFQ93573.1 - 0.022 14.6 24.2 0.05 13.5 24.2 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain VRR_NUC PF08774.11 KFQ93573.1 - 0.023 14.8 0.6 0.053 13.6 0.2 1.9 1 1 1 2 2 2 0 VRR-NUC domain Baculo_PEP_C PF04513.12 KFQ93573.1 - 0.12 12.5 2.1 0.27 11.3 2.1 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Golgin_A5 PF09787.9 KFQ93573.1 - 0.13 11.7 23.5 0.087 12.3 21.7 1.7 1 1 0 1 1 1 0 Golgin subfamily A member 5 DUF87 PF01935.17 KFQ93573.1 - 0.23 11.5 5.0 0.28 11.2 5.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain DUF4055 PF13264.6 KFQ93573.1 - 0.29 11.3 6.8 0.74 10.0 6.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) Prominin PF05478.11 KFQ93573.1 - 0.43 8.5 5.5 0.51 8.2 5.5 1.1 1 0 0 1 1 1 0 Prominin DUF3584 PF12128.8 KFQ93573.1 - 0.68 7.4 25.2 0.21 9.1 22.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.15 KFQ93573.1 - 0.7 9.4 14.7 0.92 9.0 14.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit ECH_2 PF16113.5 KFQ93573.1 - 0.9 9.0 7.2 1.5 8.2 7.2 1.4 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase DUF1664 PF07889.12 KFQ93573.1 - 0.9 9.6 10.0 4.5 7.3 8.4 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) KxDL PF10241.9 KFQ93573.1 - 1.3 9.3 13.7 1.1 9.6 10.2 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein HMMR_N PF15905.5 KFQ93573.1 - 1.6 8.1 25.2 1.5 8.3 4.2 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal FUSC PF04632.12 KFQ93573.1 - 2 6.9 12.4 2.4 6.6 12.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family GAS PF13851.6 KFQ93573.1 - 2.2 7.6 26.9 1.1 8.6 19.4 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF948 PF06103.11 KFQ93573.1 - 2.8 8.3 5.0 18 5.7 2.4 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.9 KFQ93573.1 - 4.9 7.2 26.3 0.19 11.7 4.6 3.3 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FAM76 PF16046.5 KFQ93573.1 - 5.1 6.4 19.9 15 4.8 19.9 1.9 1 1 0 1 1 1 0 FAM76 protein DUF4407 PF14362.6 KFQ93573.1 - 6 6.1 22.6 10 5.4 22.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 KFQ93573.1 - 6.8 5.5 9.8 7.5 5.3 9.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Spc7 PF08317.11 KFQ93573.1 - 7 5.4 23.8 2.3 7.0 20.6 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein Cep57_CLD_2 PF14197.6 KFQ93573.1 - 7.3 6.8 23.7 0.33 11.1 4.8 3.8 3 2 1 4 4 4 0 Centrosome localisation domain of PPC89 NACHT PF05729.12 KFQ93574.1 - 1.2e-07 31.8 0.0 5.2e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 NACHT domain NLRC4_HD2 PF17776.1 KFQ93574.1 - 3e-07 31.0 0.0 0.0069 16.9 0.0 2.8 2 0 0 2 2 2 2 NLRC4 helical domain HD2 LRR_6 PF13516.6 KFQ93574.1 - 1.4e-06 27.9 14.1 0.02 14.9 0.1 6.5 7 0 0 7 7 7 2 Leucine Rich repeat NOD2_WH PF17779.1 KFQ93574.1 - 1.4e-05 25.4 2.8 0.00019 21.7 0.8 3.2 2 1 0 2 2 2 1 NOD2 winged helix domain LRR_1 PF00560.33 KFQ93574.1 - 0.22 12.2 4.7 22 6.1 0.0 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.7 KFQ93574.1 - 2.3 8.8 12.1 0.19 12.2 0.4 4.5 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) ABC2_membrane PF01061.24 KFQ93575.1 - 1e-47 162.3 23.2 1.6e-47 161.7 23.2 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KFQ93575.1 - 5.2e-26 91.8 0.0 8.3e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFQ93575.1 - 3.1e-07 30.5 0.0 0.003 17.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFQ93575.1 - 1.9e-06 27.5 0.3 0.0003 20.3 0.1 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KFQ93575.1 - 0.00023 21.1 0.0 0.00041 20.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_13 PF13166.6 KFQ93575.1 - 0.0056 15.4 0.0 0.088 11.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFQ93575.1 - 0.017 15.2 0.1 0.034 14.2 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 KFQ93575.1 - 0.025 15.1 0.0 0.046 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KFQ93575.1 - 0.04 13.8 0.1 0.073 13.0 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 KFQ93575.1 - 0.041 13.6 0.1 0.086 12.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KFQ93575.1 - 0.068 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KFQ93575.1 - 0.09 13.3 0.1 0.18 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KFQ93575.1 - 0.1 11.5 0.1 0.17 10.8 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC2_membrane_3 PF12698.7 KFQ93575.1 - 1.9 7.5 26.5 0.27 10.3 21.2 1.9 1 1 1 2 2 2 0 ABC-2 family transporter protein DUF1440 PF07274.12 KFQ93575.1 - 2.1 8.7 6.5 0.82 10.0 1.9 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1440) DUF5566 PF17721.1 KFQ93576.1 - 4.1e-121 403.6 16.9 4.6e-121 403.4 16.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5566) PD-C2-AF1 PF09310.10 KFQ93577.1 - 5.3e-135 448.6 14.3 6e-135 448.4 14.3 1.0 1 0 0 1 1 1 1 POU domain, class 2, associating factor 1 BTG PF07742.12 KFQ93578.1 - 9.7e-44 147.9 0.1 1.3e-43 147.5 0.1 1.2 1 0 0 1 1 1 1 BTG family DUF4302 PF14135.6 KFQ93578.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4302) Pkinase PF00069.25 KFQ93579.1 - 1.8e-68 230.8 0.0 2.9e-68 230.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ93579.1 - 1.6e-36 125.9 0.0 2.7e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ93579.1 - 3e-08 33.3 0.0 6e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFQ93579.1 - 9.5e-05 21.5 0.2 0.00034 19.7 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KFQ93579.1 - 0.031 13.6 0.1 0.069 12.5 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SUKH-4 PF14435.6 KFQ93579.1 - 0.054 13.5 0.2 0.33 11.0 0.2 2.2 1 1 0 1 1 1 0 SUKH-4 immunity protein Glyco_transf_22 PF03901.17 KFQ93580.1 - 3.5e-121 405.3 31.8 4.2e-121 405.1 31.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF4231 PF14015.6 KFQ93580.1 - 0.69 10.4 0.0 0.69 10.4 0.0 2.9 4 1 0 4 4 4 0 Protein of unknown function (DUF4231) BORG_CEP PF14957.6 KFQ93582.1 - 7.4e-25 88.5 0.0 1.6e-24 87.5 0.0 1.6 1 0 0 1 1 1 1 Cdc42 effector PBD PF00786.28 KFQ93582.1 - 2e-09 37.7 0.1 3.4e-09 36.9 0.1 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain PHD PF00628.29 KFQ93583.1 - 3.8e-08 33.1 9.9 3.8e-08 33.1 9.9 2.6 2 1 1 3 3 3 1 PHD-finger PHD_4 PF16866.5 KFQ93583.1 - 0.0048 17.0 8.7 0.0048 17.0 8.7 2.7 2 1 1 3 3 3 1 PHD-finger zf-C2H2_4 PF13894.6 KFQ93583.1 - 0.012 16.4 0.8 0.012 16.4 0.8 4.0 4 1 0 4 4 4 0 C2H2-type zinc finger Lar_restr_allev PF14354.6 KFQ93583.1 - 0.047 14.1 17.2 34 4.9 13.9 3.3 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf-C2H2 PF00096.26 KFQ93583.1 - 0.048 14.1 1.2 0.048 14.1 1.2 3.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ93583.1 - 0.16 12.4 0.3 0.16 12.4 0.3 4.3 4 2 0 4 4 4 0 Zinc-finger double domain PBP1_TM PF14812.6 KFQ93583.1 - 1.1 9.7 8.2 1.7 9.1 2.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spectrin PF00435.21 KFQ93584.1 - 7.7e-68 225.6 637.0 4.4e-09 36.8 3.2 59.9 51 11 9 62 62 62 32 Spectrin repeat CH PF00307.31 KFQ93584.1 - 2.7e-36 124.1 6.0 5.4e-21 74.8 0.0 6.3 6 0 0 6 6 6 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFQ93584.1 - 9e-06 25.4 0.0 0.084 12.7 0.0 3.5 2 0 0 2 2 2 2 CAMSAP CH domain TEX12 PF15219.6 KFQ93584.1 - 0.35 11.2 12.5 0.41 11.0 0.2 6.7 5 0 0 5 5 5 0 Testis-expressed 12 V-SNARE_C PF12352.8 KFQ93584.1 - 1.8 8.9 16.9 10 6.5 0.0 7.1 5 0 0 5 5 5 0 Snare region anchored in the vesicle membrane C-terminus GM_CSF PF01109.17 KFQ93584.1 - 1.9 8.7 13.6 0.021 15.0 0.4 5.0 5 0 0 5 5 5 0 Granulocyte-macrophage colony-stimulating factor FERM_N_2 PF18038.1 KFQ93584.1 - 2 9.3 7.1 3.8 8.4 0.3 5.2 3 0 0 3 3 3 0 FERM N-terminal domain Myc_target_1 PF15179.6 KFQ93585.1 - 4.1e-71 238.9 7.7 4.5e-71 238.7 7.7 1.0 1 0 0 1 1 1 1 Myc target protein 1 Hormone_2 PF00123.20 KFQ93586.1 - 6e-24 83.6 4.6 9.5e-12 44.6 0.2 3.0 3 0 0 3 3 3 2 Peptide hormone F-box PF00646.33 KFQ93587.1 - 3.2e-07 30.0 0.0 7.4e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 F-box domain IBR PF01485.21 KFQ93587.1 - 1.8e-05 24.8 10.7 1.8e-05 24.8 10.7 1.8 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain F-box-like PF12937.7 KFQ93587.1 - 0.033 14.1 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 F-box-like DUF1663 PF07909.11 KFQ93587.1 - 0.095 11.4 0.4 0.15 10.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1663) Prok-RING_1 PF14446.6 KFQ93587.1 - 7.9 6.5 14.4 3.3 7.7 1.1 3.3 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 RGS PF00615.19 KFQ93588.1 - 4.9e-36 123.6 1.0 6.7e-36 123.1 1.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain 7tm_1 PF00001.21 KFQ93589.1 - 4.4e-58 196.7 24.9 5.2e-58 196.4 24.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFQ93589.1 - 6e-09 35.7 14.6 7.5e-09 35.4 14.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 KFQ93589.1 - 0.00028 20.6 21.6 0.00043 20.0 21.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFQ93589.1 - 0.0069 16.2 14.3 0.015 15.1 14.3 1.5 1 1 0 1 1 1 1 Olfactory receptor DUF2824 PF11039.8 KFQ93589.1 - 0.0087 16.0 0.2 0.035 14.1 0.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2824) CitMHS PF03600.16 KFQ93589.1 - 0.4 9.8 6.1 0.56 9.3 6.1 1.3 1 0 0 1 1 1 0 Citrate transporter DUF1170 PF06663.13 KFQ93590.1 - 7.8e-57 192.4 1.0 1.7e-56 191.3 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1170) CRIC_ras_sig PF10534.9 KFQ93590.1 - 2.7e-37 126.8 0.1 5.9e-37 125.7 0.1 1.6 1 0 0 1 1 1 1 Connector enhancer of kinase suppressor of ras SAM_1 PF00536.30 KFQ93590.1 - 1.3e-12 47.9 0.4 2.8e-12 46.9 0.4 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 KFQ93590.1 - 3.6e-12 46.7 0.7 3.6e-12 46.7 0.7 2.1 2 0 0 2 2 2 1 PH domain PDZ PF00595.24 KFQ93590.1 - 5.8e-10 39.4 0.0 1.4e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain SAM_2 PF07647.17 KFQ93590.1 - 2.4e-08 34.0 0.5 4.9e-08 33.0 0.5 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ_6 PF17820.1 KFQ93590.1 - 8.8e-07 28.7 0.4 2.7e-06 27.1 0.1 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KFQ93590.1 - 0.0029 17.9 0.0 0.0055 17.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Tiam_CC_Ex PF18385.1 KFQ93591.1 - 8.2e-56 186.5 0.1 1.2e-55 185.9 0.1 1.3 1 0 0 1 1 1 1 T-lymphoma invasion and metastasis CC-Ex domain PH PF00169.29 KFQ93591.1 - 7.2e-09 36.1 0.2 2.5e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 KFQ93591.1 - 1.9e-07 31.4 0.0 5.6e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 KFQ93591.1 - 0.0097 15.7 0.0 0.022 14.6 0.0 1.5 1 1 0 1 1 1 1 Pleckstrin homology domain Nup96 PF12110.8 KFQ93591.1 - 0.018 14.2 0.1 0.026 13.6 0.1 1.2 1 0 0 1 1 1 0 Nuclear protein 96 DUF4660 PF15559.6 KFQ93591.1 - 0.077 13.3 0.6 0.32 11.3 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4660) Arm-DNA-bind_5 PF17293.2 KFQ93591.1 - 0.088 13.3 0.2 0.17 12.3 0.2 1.4 1 0 0 1 1 1 0 Arm DNA-binding domain Hydrolase_4 PF12146.8 KFQ93591.1 - 0.2 10.9 0.0 0.25 10.6 0.0 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 RhoGEF PF00621.20 KFQ93592.1 - 1.1e-26 94.2 0.7 1.1e-26 94.2 0.7 2.1 3 0 0 3 3 3 1 RhoGEF domain DUF1924 PF09086.11 KFQ93592.1 - 0.16 12.4 1.9 0.31 11.4 0.4 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1924) FadA PF09403.10 KFQ93592.1 - 0.35 11.4 5.1 0.69 10.4 0.4 2.6 2 0 0 2 2 2 0 Adhesion protein FadA RrnaAD PF00398.20 KFQ93593.1 - 4.1e-41 140.8 0.0 5.1e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Amelogenin PF02948.15 KFQ93593.1 - 0.0022 18.7 0.6 0.0033 18.1 0.1 1.5 2 0 0 2 2 2 1 Amelogenin PMP22_Claudin PF00822.20 KFQ93594.1 - 5.4e-28 98.0 6.5 7.1e-28 97.6 6.5 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFQ93594.1 - 4.2e-08 33.2 10.3 1.2e-06 28.5 8.4 2.6 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.12 KFQ93594.1 - 0.00094 18.7 0.9 0.0015 18.0 0.3 1.7 1 1 0 1 1 1 1 Clc-like DUF872 PF05915.12 KFQ93594.1 - 0.13 12.4 0.9 0.24 11.6 0.2 1.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF3185 PF11381.8 KFQ93594.1 - 2.1 8.4 6.6 1.4 9.0 0.3 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3185) NAD_binding_6 PF08030.12 KFQ93595.1 - 2.2e-27 96.1 0.1 1.7e-26 93.2 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KFQ93595.1 - 4.4e-27 94.7 1.7 8.7e-27 93.7 1.7 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFQ93595.1 - 2.9e-24 85.2 0.0 6e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.24 KFQ93595.1 - 0.0002 21.7 0.0 0.00039 20.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain TENA_THI-4 PF03070.16 KFQ93598.1 - 0.032 14.0 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 TENA/THI-4/PQQC family TFIIA PF03153.13 KFQ93599.1 - 3.5 7.5 15.0 4.7 7.1 15.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BAF250_C PF12031.8 KFQ93600.1 - 1.3e-121 404.7 0.0 2.4e-121 403.9 0.0 1.5 1 0 0 1 1 1 1 SWI/SNF-like complex subunit BAF250/Osa ARID PF01388.21 KFQ93600.1 - 1.2e-17 64.3 0.0 2.9e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF1358 PF07096.11 KFQ93601.1 - 2.7e-44 149.8 3.0 3e-44 149.7 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1358) DHHC PF01529.20 KFQ93602.1 - 1.3e-35 122.5 8.1 1.3e-35 122.5 8.1 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Imm17 PF15562.6 KFQ93602.1 - 9.1 6.2 9.2 0.78 9.7 0.1 2.6 3 0 0 3 3 3 0 Immunity protein 17 BAR_3_WASP_bdg PF10456.9 KFQ93603.1 - 1.2e-113 378.4 0.7 1.6e-113 378.0 0.7 1.1 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.24 KFQ93603.1 - 1.5e-23 82.9 0.2 3.2e-23 81.9 0.2 1.6 1 0 0 1 1 1 1 PX domain SH3_1 PF00018.28 KFQ93603.1 - 1.2e-09 37.6 0.4 3.5e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFQ93603.1 - 9.4e-09 35.0 0.2 2.4e-08 33.7 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KFQ93603.1 - 5.7e-07 29.1 0.0 1.2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.10 KFQ93603.1 - 0.0095 15.5 0.0 1.5 8.3 0.1 2.4 1 1 1 2 2 2 2 Vps5 C terminal like Syja_N PF02383.18 KFQ93604.1 - 2.4e-66 224.2 0.1 8.8e-66 222.4 0.0 1.8 2 0 0 2 2 2 1 SacI homology domain DUF1866 PF08952.11 KFQ93604.1 - 2.6e-54 183.0 0.9 4.1e-54 182.4 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1866) Exo_endo_phos PF03372.23 KFQ93604.1 - 1.9e-13 50.5 0.0 3.3e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RRM_1 PF00076.22 KFQ93604.1 - 0.035 13.9 0.2 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tfb5 PF06331.12 KFQ93605.1 - 2e-20 72.5 0.1 2.2e-20 72.4 0.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 MIG-14_Wnt-bd PF06664.12 KFQ93607.1 - 1.2e-92 310.3 36.3 1.2e-92 310.3 36.3 2.0 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion PSII_Ycf12 PF05969.11 KFQ93607.1 - 5.2 7.1 6.1 2.5 8.1 0.1 2.8 2 1 0 2 2 2 0 Photosystem II complex subunit Ycf12 Tctex-1 PF03645.13 KFQ93608.1 - 1.7e-33 114.9 0.7 1.9e-33 114.8 0.7 1.0 1 0 0 1 1 1 1 Tctex-1 family C2 PF00168.30 KFQ93609.1 - 5.2e-18 65.2 0.0 7.1e-17 61.6 0.0 2.3 2 0 0 2 2 2 1 C2 domain FYVE_2 PF02318.16 KFQ93609.1 - 6.4e-16 58.6 11.9 6.4e-16 58.6 11.9 1.8 2 0 0 2 2 2 1 FYVE-type zinc finger ERM PF00769.19 KFQ93610.1 - 1.9e-70 237.5 42.1 1.9e-70 237.5 42.1 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_C PF09380.10 KFQ93610.1 - 5.5e-28 97.2 0.2 1.9e-27 95.4 0.0 2.1 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_M PF00373.18 KFQ93610.1 - 9.4e-28 97.0 0.2 9.4e-28 97.0 0.2 3.4 2 1 1 3 3 3 1 FERM central domain FERM_N PF09379.10 KFQ93610.1 - 3.1e-14 52.7 1.5 7.5e-14 51.4 0.1 2.4 3 0 0 3 3 3 1 FERM N-terminal domain RhoGAP PF00620.27 KFQ93611.1 - 1.4e-42 145.1 0.6 3.9e-42 143.6 0.6 1.8 1 0 0 1 1 1 1 RhoGAP domain AMPKBI PF04739.15 KFQ93611.1 - 3.2 8.1 4.9 1.1 9.6 0.3 2.6 3 0 0 3 3 3 0 5'-AMP-activated protein kinase beta subunit, interaction domain Radial_spoke_3 PF06098.11 KFQ93612.1 - 1.1e-129 431.8 11.9 1.3e-129 431.6 11.9 1.0 1 0 0 1 1 1 1 Radial spoke protein 3 SET PF00856.28 KFQ93613.1 - 0.0045 17.4 0.0 0.078 13.4 0.0 2.1 1 1 1 2 2 2 1 SET domain zf-C2H2_4 PF13894.6 KFQ93613.1 - 6.1 8.0 6.8 16 6.6 0.2 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFQ93613.1 - 7.1 7.3 12.1 1 10.0 0.9 3.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ93614.1 - 6.8e-20 70.1 54.8 0.0031 18.2 5.1 7.6 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2 PF00096.26 KFQ93614.1 - 6.2e-18 64.2 62.0 0.0012 19.2 7.8 7.7 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ93614.1 - 2.1e-13 50.0 63.7 0.0046 17.3 4.4 8.7 8 1 0 8 8 8 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFQ93614.1 - 2.1e-05 24.7 31.4 0.56 10.6 0.3 6.3 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KFQ93614.1 - 0.00097 19.4 25.2 0.059 13.7 7.1 3.8 1 1 2 3 3 3 3 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 KFQ93614.1 - 0.023 15.4 20.1 0.053 14.2 1.7 4.3 2 1 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 KFQ93614.1 - 0.046 14.1 33.0 6.8 7.1 0.1 4.9 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KFQ93614.1 - 0.056 13.5 0.1 0.056 13.5 0.1 7.3 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFQ93614.1 - 0.072 12.9 0.1 0.072 12.9 0.1 5.5 6 0 0 6 6 6 0 zinc-finger C2H2-type Acyltransf_C PF16076.5 KFQ93614.1 - 0.075 13.1 2.0 8.6 6.5 0.4 2.6 2 1 0 2 2 2 0 Acyltransferase C-terminus zf-met PF12874.7 KFQ93614.1 - 0.38 11.2 23.5 1.5 9.3 0.1 5.7 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Desulfoferrod_N PF06397.12 KFQ93614.1 - 6.5 6.5 6.6 49 3.6 0.0 3.8 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain zf-C2HC_2 PF13913.6 KFQ93615.1 - 2.9e-16 58.9 5.5 8.3e-09 35.1 0.1 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-CpG_bind_C PF12269.8 KFQ93615.1 - 0.00085 19.2 0.0 0.45 10.3 0.0 2.1 2 0 0 2 2 2 2 CpG binding protein zinc finger C terminal domain NeA_P2 PF12312.8 KFQ93615.1 - 0.0027 17.2 1.0 0.0038 16.7 1.0 1.4 1 0 0 1 1 1 1 Nepovirus subgroup A polyprotein zf-C2H2_4 PF13894.6 KFQ93615.1 - 0.014 16.1 14.7 0.072 14.0 1.7 3.9 4 1 0 4 4 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFQ93615.1 - 0.024 15.1 12.4 0.52 10.9 0.3 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type DNA_RNApol_7kD PF03604.13 KFQ93615.1 - 0.034 13.8 1.0 6.8 6.5 0.1 2.7 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_11 PF16622.5 KFQ93615.1 - 0.04 13.7 1.5 1.7 8.5 0.1 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type CAP_N PF01213.19 KFQ93615.1 - 0.053 13.0 0.9 0.077 12.5 0.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-RING_7 PF02591.15 KFQ93615.1 - 0.13 12.5 4.9 4 7.7 0.7 3.2 3 1 0 3 3 3 0 C4-type zinc ribbon domain zf-CHCC PF10276.9 KFQ93615.1 - 0.13 12.3 3.6 2 8.5 0.1 2.8 4 0 0 4 4 3 0 Zinc-finger domain DZR PF12773.7 KFQ93615.1 - 0.14 12.2 2.1 1.4 9.0 0.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-C2H2_6 PF13912.6 KFQ93615.1 - 0.22 11.6 5.9 11 6.2 0.1 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 KFQ93615.1 - 0.22 11.8 3.1 1.7 9.0 0.3 2.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Prok-RING_1 PF14446.6 KFQ93615.1 - 0.27 11.2 2.4 10 6.1 0.0 2.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zinc_ribbon_4 PF13717.6 KFQ93615.1 - 0.61 10.1 5.9 1.9 8.4 0.5 2.8 3 0 0 3 3 3 0 zinc-ribbon domain YacG PF03884.14 KFQ93615.1 - 0.7 9.7 7.4 0.33 10.7 0.9 2.7 2 1 1 3 3 3 0 DNA gyrase inhibitor YacG zf_UBZ PF18439.1 KFQ93615.1 - 3.9 7.1 10.0 4.4 7.0 0.3 3.2 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-H2C2_2 PF13465.6 KFQ93615.1 - 5.4 7.6 11.3 2.9 8.5 0.2 4.2 5 0 0 5 5 5 0 Zinc-finger double domain DUF2256 PF10013.9 KFQ93615.1 - 6.6 6.9 8.3 25 5.1 0.2 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) LTV PF04180.14 KFQ93616.1 - 1e-87 295.4 17.7 1.5e-86 291.6 17.7 2.3 1 1 0 1 1 1 1 Low temperature viability protein UPF0767 PF15990.5 KFQ93616.1 - 3.7 7.8 7.1 2.6 8.2 4.7 2.0 2 0 0 2 2 2 0 UPF0767 family RPEL PF02755.15 KFQ93617.1 - 6.8e-28 95.5 21.9 1.3e-07 31.1 2.5 4.6 4 0 0 4 4 4 4 RPEL repeat SieB PF14163.6 KFQ93617.1 - 0.25 10.9 2.7 1.3 8.6 2.7 2.2 1 1 0 1 1 1 0 Super-infection exclusion protein B Alpha_L_fucos PF01120.17 KFQ93618.1 - 1.1e-103 347.4 1.0 1.2e-103 347.2 1.0 1.0 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 KFQ93618.1 - 1.3e-28 99.4 0.1 3e-28 98.2 0.1 1.7 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain Peroxin-3 PF04882.12 KFQ93619.1 - 5.1e-66 223.6 6.7 2.6e-49 168.5 1.0 3.0 1 1 1 2 2 2 2 Peroxin-3 DUF3631 PF12307.8 KFQ93619.1 - 0.11 12.7 0.3 0.37 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3631) dCMP_cyt_deam_1 PF00383.23 KFQ93620.1 - 6.1e-19 67.8 1.0 8.4e-19 67.3 1.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFQ93620.1 - 1.1e-17 64.0 0.1 1.5e-17 63.6 0.1 1.2 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 KFQ93620.1 - 0.0004 20.5 0.1 0.00061 19.9 0.1 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 KFQ93620.1 - 0.00046 20.3 4.0 0.01 15.9 4.0 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC2 PF18772.1 KFQ93620.1 - 0.00057 20.0 0.0 0.0008 19.5 0.0 1.2 1 0 0 1 1 1 1 APOBEC2 NAD1 PF18778.1 KFQ93620.1 - 0.0013 18.9 0.0 0.0018 18.4 0.0 1.2 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC3 PF18771.1 KFQ93620.1 - 0.0022 18.1 0.0 0.0032 17.6 0.0 1.2 1 0 0 1 1 1 1 APOBEC3 APOBEC4_like PF18774.1 KFQ93620.1 - 0.0062 16.5 0.1 0.0091 15.9 0.1 1.2 1 0 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase NAD2 PF18782.1 KFQ93620.1 - 0.032 14.3 0.0 0.046 13.8 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 APOBEC_N PF08210.11 KFQ93620.1 - 0.044 13.7 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Inv-AAD PF18785.1 KFQ93620.1 - 0.053 13.4 0.1 0.093 12.6 0.1 1.4 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase DUF929 PF06053.11 KFQ93620.1 - 0.2 11.0 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF929) Far-17a_AIG1 PF04750.14 KFQ93621.1 - 2.2e-64 216.5 10.0 2.5e-64 216.3 10.0 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein FancD2 PF14631.6 KFQ93621.1 - 0.14 9.6 0.1 0.17 9.3 0.1 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease zf-C2H2 PF00096.26 KFQ93622.1 - 2.7e-18 65.3 27.8 0.00011 22.4 1.4 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFQ93622.1 - 1.1e-10 41.5 23.7 0.0021 18.3 1.5 4.9 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KFQ93622.1 - 1.1e-10 41.4 37.2 1.8e-06 28.1 1.0 5.3 5 0 0 5 5 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ93622.1 - 1.4e-09 37.9 23.8 0.07 14.0 0.4 5.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 KFQ93622.1 - 8.6e-05 22.8 25.4 0.0093 16.3 2.8 5.1 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFQ93622.1 - 0.00071 19.3 21.7 0.15 11.8 0.8 4.7 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 KFQ93622.1 - 0.064 13.9 7.2 8.2 7.1 0.4 4.2 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats NOA36 PF06524.12 KFQ93622.1 - 0.19 11.0 22.8 0.17 11.2 14.0 2.4 2 0 0 2 2 2 0 NOA36 protein zf-C2H2_2 PF12756.7 KFQ93622.1 - 0.58 10.5 18.3 0.21 11.9 4.2 4.0 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) RRN3 PF05327.11 KFQ93622.1 - 4 5.9 7.0 7.2 5.0 7.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 zf-Di19 PF05605.12 KFQ93622.1 - 7 7.0 14.8 4.2 7.8 4.0 3.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding 7tm_2 PF00002.24 KFQ93623.1 - 1.8e-48 165.0 17.3 1.8e-48 165.0 17.3 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) CUB PF00431.20 KFQ93623.1 - 2.4e-24 85.8 0.0 5.9e-24 84.5 0.0 1.7 1 0 0 1 1 1 1 CUB domain GPS PF01825.21 KFQ93623.1 - 2.1e-17 63.3 2.9 6.9e-17 61.7 2.9 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Pentaxin PF00354.17 KFQ93623.1 - 1.6e-09 37.7 0.1 5.2e-09 36.1 0.1 1.8 1 0 0 1 1 1 1 Pentaxin family Frizzled PF01534.17 KFQ93623.1 - 0.0013 17.9 20.3 0.76 8.8 20.3 2.7 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region CUB_2 PF02408.20 KFQ93623.1 - 0.02 14.7 0.1 0.09 12.5 0.1 2.2 1 0 0 1 1 1 0 CUB-like domain FIVAR PF07554.13 KFQ93623.1 - 0.19 12.5 3.7 0.13 13.0 0.7 2.4 2 0 0 2 2 2 0 FIVAR domain Vta1 PF04652.16 KFQ93625.1 - 2.4e-40 137.8 2.8 4.9e-40 136.8 1.5 1.9 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 KFQ93625.1 - 1.7e-18 66.0 0.6 1.7e-18 66.0 0.6 1.6 2 0 0 2 2 2 1 Vta1 C-terminal domain DAG_kinase_N PF14513.6 KFQ93625.1 - 0.13 12.4 0.3 0.36 11.0 0.0 1.8 2 1 0 2 2 2 0 Diacylglycerol kinase N-terminus 7tm_1 PF00001.21 KFQ93626.1 - 1.3e-53 182.0 14.0 1.6e-53 181.7 14.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFQ93626.1 - 1.7e-09 37.5 9.2 2.2e-09 37.1 9.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.9 KFQ93626.1 - 8.9e-08 31.8 13.1 1.2e-07 31.3 13.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 KFQ93626.1 - 0.22 10.8 15.7 0.5 9.6 15.7 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw MAP17 PF15807.5 KFQ93628.1 - 0.36 11.1 5.0 0.37 11.0 5.0 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 V_ATPase_I PF01496.19 KFQ93628.1 - 2.8 5.7 3.6 2.9 5.7 3.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Headcase PF16002.5 KFQ93629.1 - 4.2e-83 277.7 3.9 4.2e-83 277.7 3.9 1.7 2 0 0 2 2 2 1 Headcase protein HECA PF15353.6 KFQ93629.1 - 4.7e-40 136.0 8.8 1.2e-39 134.6 8.8 1.7 1 0 0 1 1 1 1 Headcase protein family homologue VATC PF18716.1 KFQ93629.1 - 1.3 8.9 15.7 0.83 9.6 1.2 5.2 4 1 0 4 4 4 0 Vms1-associating treble clef domain HypA PF01155.19 KFQ93629.1 - 5.5 7.0 7.6 9.6 6.3 4.3 2.6 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 KFQ93629.1 - 7.2 6.5 10.9 5.8 6.8 0.4 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Costars PF14705.6 KFQ93630.1 - 3.7e-31 107.1 0.4 4.1e-31 107.0 0.4 1.0 1 0 0 1 1 1 1 Costars DUF4061 PF13270.6 KFQ93631.1 - 5.7e-32 109.9 4.3 7.9e-32 109.4 4.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) tRNA-synt_His PF13393.6 KFQ93631.1 - 0.046 13.0 0.3 0.06 12.6 0.3 1.1 1 0 0 1 1 1 0 Histidyl-tRNA synthetase PMP22_Claudin PF00822.20 KFQ93632.1 - 9.7e-11 41.8 3.4 1.4e-10 41.3 3.4 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 KFQ93632.1 - 0.00062 20.0 5.9 0.0017 18.6 6.0 1.7 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Pox_A14 PF05767.12 KFQ93632.1 - 0.77 10.0 8.0 1.2 9.3 4.5 2.3 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 PMP22_Claudin PF00822.20 KFQ93633.1 - 1.2e-09 38.3 9.5 1.5e-09 38.0 9.5 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 KFQ93633.1 - 0.00092 19.5 7.8 0.0023 18.2 7.8 1.7 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PalH PF08733.10 KFQ93633.1 - 0.067 12.2 5.1 0.087 11.8 5.1 1.1 1 0 0 1 1 1 0 PalH/RIM21 PTR2 PF00854.21 KFQ93633.1 - 0.62 8.8 9.3 2.2 7.0 1.9 2.4 1 1 1 2 2 2 0 POT family Pox_A14 PF05767.12 KFQ93633.1 - 2.1 8.5 8.5 0.28 11.4 4.1 1.7 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 SUR7 PF06687.12 KFQ93633.1 - 4.5 6.8 15.8 1.8 8.1 13.3 1.6 1 1 1 2 2 2 0 SUR7/PalI family zf-A20 PF01754.16 KFQ93634.1 - 7.4e-37 124.9 64.2 1.5e-08 34.4 2.9 6.8 6 0 0 6 6 6 6 A20-like zinc finger OTU PF02338.19 KFQ93634.1 - 1e-29 103.6 0.0 2.9e-29 102.1 0.0 1.9 1 0 0 1 1 1 1 OTU-like cysteine protease HLH PF00010.26 KFQ93635.1 - 1.9e-12 46.9 0.3 3.6e-12 46.0 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tissue_fac PF01108.17 KFQ93636.1 - 2e-18 66.2 0.0 2.4e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Tissue factor GYF PF02213.16 KFQ93636.1 - 0.026 14.2 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 GYF domain Tissue_fac PF01108.17 KFQ93637.1 - 1.1e-32 112.1 2.0 1.1e-32 112.0 0.9 1.6 2 0 0 2 2 2 1 Tissue factor Interfer-bind PF09294.10 KFQ93637.1 - 1.5e-16 60.6 0.5 2.8e-16 59.7 0.2 1.6 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.21 KFQ93637.1 - 0.28 11.6 3.5 1.1 9.7 1.1 2.9 3 1 0 3 3 3 0 Fibronectin type III domain Tissue_fac PF01108.17 KFQ93638.1 - 1.3e-26 92.5 0.2 3.5e-26 91.1 0.2 1.8 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.10 KFQ93638.1 - 6.3e-19 68.2 2.4 8.3e-19 67.8 0.2 2.3 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III EamA PF00892.20 KFQ93639.1 - 0.012 15.7 11.3 0.015 15.4 11.3 1.1 1 0 0 1 1 1 0 EamA-like transporter family NnrU PF07298.11 KFQ93639.1 - 0.11 12.0 1.4 0.17 11.4 0.8 1.6 1 1 0 1 1 1 0 NnrU protein DUF2070 PF09843.9 KFQ93639.1 - 0.38 9.0 6.8 0.5 8.6 6.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4199 PF13858.6 KFQ93639.1 - 2.7 8.4 10.5 0.68 10.3 4.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) 7TMR-DISM_7TM PF07695.11 KFQ93639.1 - 5.7 6.8 10.7 0.43 10.4 4.0 1.7 1 1 0 2 2 2 0 7TM diverse intracellular signalling WD40 PF00400.32 KFQ93640.1 - 7.6e-23 80.4 14.1 4e-06 27.5 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.11 KFQ93640.1 - 5.9e-05 23.0 0.1 0.00067 19.6 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KFQ93640.1 - 0.033 14.5 0.6 1.6 9.1 0.1 3.1 1 1 4 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4071 PF13281.6 KFQ93641.1 - 1.4e-155 517.9 1.9 3.5e-155 516.6 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4071) Pkinase PF00069.25 KFQ93641.1 - 8.9e-64 215.4 0.0 2.1e-63 214.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ93641.1 - 4.8e-42 144.0 0.0 8.2e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFQ93641.1 - 0.00048 19.0 0.0 0.001 18.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFQ93641.1 - 0.0021 17.4 0.0 0.0053 16.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like MAP7 PF05672.11 KFQ93642.1 - 4.2e-43 146.9 82.0 4.2e-43 146.9 82.0 3.2 3 0 0 3 3 3 2 MAP7 (E-MAP-115) family THRAP3_BCLAF1 PF15440.6 KFQ93644.1 - 5.6e-188 627.1 104.3 5.6e-188 627.1 104.3 2.5 2 1 1 3 3 3 1 THRAP3/BCLAF1 family GRP PF07172.11 KFQ93644.1 - 0.68 10.7 15.8 0.035 14.8 5.2 3.7 2 1 0 2 2 2 0 Glycine rich protein family Mito_fiss_reg PF05308.11 KFQ93645.1 - 2.3e-79 267.0 0.2 3e-79 266.6 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial fission regulator PDEase_I PF00233.19 KFQ93646.1 - 6.4e-76 255.2 0.6 8.5e-76 254.8 0.6 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Cmyb_C PF09316.10 KFQ93647.1 - 1e-76 256.2 2.9 1.9e-76 255.3 2.9 1.4 1 0 0 1 1 1 1 C-myb, C-terminal Myb_DNA-binding PF00249.31 KFQ93647.1 - 4.1e-50 167.7 21.0 1.6e-16 60.2 0.5 3.9 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFQ93647.1 - 2.8e-39 133.1 18.0 6.4e-17 61.6 1.5 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain LMSTEN PF07988.12 KFQ93647.1 - 1e-26 92.1 0.6 2e-26 91.2 0.6 1.5 1 0 0 1 1 1 1 LMSTEN motif Myb_DNA-bind_7 PF15963.5 KFQ93647.1 - 2.2e-08 33.9 9.0 0.00034 20.4 0.1 3.8 2 1 2 4 4 4 2 Myb DNA-binding like SLIDE PF09111.10 KFQ93647.1 - 1.2e-05 25.2 0.3 2.7 8.1 0.0 4.0 2 1 2 4 4 4 3 SLIDE SANT_DAMP1_like PF16282.5 KFQ93647.1 - 0.00058 20.0 3.7 1.6 8.9 0.0 3.4 1 1 2 3 3 3 2 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 KFQ93647.1 - 0.059 13.5 8.2 1.7 8.8 0.8 3.5 1 1 2 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Nore1-SARAH PF16517.5 KFQ93647.1 - 0.1 12.5 1.0 1 9.3 0.0 2.6 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Spore_III_AB PF09548.10 KFQ93647.1 - 0.61 10.2 3.6 0.66 10.1 0.0 2.7 3 1 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) GTP_EFTU PF00009.27 KFQ93648.1 - 7e-48 162.8 0.0 1.4e-47 161.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFQ93648.1 - 8.4e-31 106.6 1.2 3.2e-30 104.7 0.1 2.5 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain HBS1_N PF08938.10 KFQ93648.1 - 1.3e-19 70.3 0.3 2.9e-19 69.2 0.3 1.6 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D2 PF03144.25 KFQ93648.1 - 3.2e-07 30.6 0.3 1.3e-06 28.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFQ93648.1 - 4e-07 30.1 0.8 6.9e-05 22.9 0.1 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KFQ93648.1 - 0.0037 17.6 0.4 0.017 15.4 0.0 2.3 3 0 0 3 3 3 1 AAA domain DUF1296 PF06972.11 KFQ93648.1 - 0.098 12.8 0.2 0.3 11.3 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) AAA_29 PF13555.6 KFQ93648.1 - 0.27 11.0 3.0 1.3 8.8 0.0 2.9 3 0 0 3 3 3 0 P-loop containing region of AAA domain Aldedh PF00171.22 KFQ93649.1 - 2.2e-172 573.8 0.0 2.5e-172 573.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KFQ93649.1 - 0.043 13.3 0.1 0.45 9.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Yae1_N PF09811.9 KFQ93651.1 - 7e-08 32.0 42.4 71 3.2 30.3 5.0 2 1 1 3 3 3 1 Essential protein Yae1, N terminal Sugar_tr PF00083.24 KFQ93652.1 - 3e-102 342.8 26.4 1.2e-77 261.7 14.4 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFQ93652.1 - 3.3e-29 101.9 36.0 4.3e-26 91.7 20.0 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_3 PF16080.5 KFQ93652.1 - 0.02 14.6 1.0 0.62 9.9 0.0 3.3 2 0 0 2 2 2 0 Bacteriophage holin family HP1 TBP PF00352.21 KFQ93653.1 - 1.7e-43 146.4 0.2 5.8e-23 80.7 0.1 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KFQ93653.1 - 0.006 16.7 0.0 0.0099 16.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3378) HLH PF00010.26 KFQ93654.1 - 7.6e-16 57.8 0.2 1.1e-15 57.3 0.2 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hydrolase PF00702.26 KFQ93655.1 - 6.3e-07 29.9 0.0 8.5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribosomal_L7Ae PF01248.26 KFQ93656.1 - 4.4e-30 103.3 1.9 5.4e-30 103.0 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family MFS_1 PF07690.16 KFQ93657.1 - 1.1e-36 126.5 69.6 1.4e-22 80.1 36.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFQ93657.1 - 0.00078 18.4 27.5 0.025 13.5 5.4 3.6 1 1 1 2 2 2 2 MFS_1 like family LacY_symp PF01306.19 KFQ93657.1 - 0.0021 16.9 14.4 0.14 10.9 0.4 2.3 1 1 1 2 2 2 2 LacY proton/sugar symporter DUF4112 PF13430.6 KFQ93657.1 - 0.67 10.2 4.0 5.7 7.3 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4112) CN_hydrolase PF00795.22 KFQ93658.1 - 3.6e-21 75.7 0.0 5.1e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CN_hydrolase PF00795.22 KFQ93659.1 - 3.4e-23 82.3 0.0 6.3e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CN_hydrolase PF00795.22 KFQ93660.1 - 3e-22 79.2 0.0 4.5e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase 7tm_1 PF00001.21 KFQ93661.1 - 7.5e-60 202.5 16.4 1e-59 202.0 16.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ93661.1 - 3.7e-06 26.5 20.2 3.7e-06 26.5 20.2 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFQ93661.1 - 0.00046 19.9 20.0 0.00046 19.9 20.0 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx AWPM-19 PF05512.11 KFQ93661.1 - 0.055 13.7 3.5 0.15 12.2 0.2 2.3 2 0 0 2 2 2 0 AWPM-19-like family Syntaxin_2 PF14523.6 KFQ93663.1 - 7.2e-30 103.4 17.8 2.1e-28 98.6 9.5 2.1 2 0 0 2 2 2 2 Syntaxin-like protein SNARE PF05739.19 KFQ93663.1 - 2.4e-20 72.3 1.7 6.5e-20 70.9 1.7 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KFQ93663.1 - 4e-11 43.0 11.2 4e-11 43.0 11.2 2.2 2 1 0 2 2 2 1 Syntaxin DUF3040 PF11239.8 KFQ93663.1 - 0.0076 16.5 0.1 0.05 13.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3040) DASH_Dad4 PF08650.10 KFQ93663.1 - 0.026 14.5 4.4 0.45 10.5 0.1 2.9 2 1 1 3 3 3 0 DASH complex subunit Dad4 CCDC-167 PF15188.6 KFQ93663.1 - 0.042 14.2 14.0 0.12 12.8 1.6 3.1 2 2 1 3 3 3 0 Coiled-coil domain-containing protein 167 Synaptobrevin PF00957.21 KFQ93663.1 - 0.26 11.1 10.4 0.028 14.2 3.4 2.6 2 1 0 2 2 2 0 Synaptobrevin T3SS_needle_E PF08988.10 KFQ93663.1 - 0.26 11.5 0.3 0.26 11.5 0.3 3.8 4 1 1 5 5 5 0 Type III secretion system, cytoplasmic E component of needle Prominin PF05478.11 KFQ93663.1 - 0.7 7.8 9.2 0.11 10.5 0.7 2.1 2 0 0 2 2 2 0 Prominin VIT1 PF01988.19 KFQ93663.1 - 0.83 9.5 2.0 7.3 6.4 0.1 2.2 2 0 0 2 2 2 0 VIT family FUSC PF04632.12 KFQ93663.1 - 1.4 7.3 5.6 0.82 8.1 3.3 1.5 1 1 1 2 2 2 0 Fusaric acid resistance protein family Cep57_CLD_2 PF14197.6 KFQ93663.1 - 1.5 8.9 9.8 0.92 9.6 0.2 2.9 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 PCRF PF03462.18 KFQ93663.1 - 2.9 7.7 11.2 1.6 8.5 2.1 2.3 2 1 0 2 2 2 0 PCRF domain IZUMO PF15005.6 KFQ93663.1 - 3.5 8.1 7.0 2.3 8.7 2.0 2.6 2 2 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated FapA PF03961.13 KFQ93663.1 - 3.8 6.0 9.6 0.43 9.1 1.6 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A Spore_III_AB PF09548.10 KFQ93663.1 - 4.5 7.4 8.9 1.6 8.8 0.3 2.8 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) TMPIT PF07851.13 KFQ93663.1 - 6.3 5.9 10.7 2 7.6 0.7 2.2 1 1 0 2 2 2 0 TMPIT-like protein OmpH PF03938.14 KFQ93663.1 - 9 6.6 22.9 0.38 11.1 9.5 2.4 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Cu2_monooxygen PF01082.20 KFQ93664.1 - 1.1e-49 168.0 1.2 2.3e-49 167.0 1.2 1.6 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 KFQ93664.1 - 8.7e-43 145.5 0.0 1.8e-42 144.6 0.0 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DOMON PF03351.17 KFQ93664.1 - 8.3e-12 45.4 0.4 1.5e-11 44.6 0.4 1.4 1 0 0 1 1 1 1 DOMON domain DUF1987 PF09345.10 KFQ93664.1 - 0.14 11.8 0.2 0.78 9.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1987) Cys_knot PF00007.22 KFQ93665.1 - 2.4e-16 59.9 9.9 2.4e-16 59.9 9.9 3.0 3 1 0 3 3 3 1 Cystine-knot domain VWC PF00093.18 KFQ93665.1 - 3.5e-10 40.0 9.9 3.5e-10 40.0 9.9 3.8 2 1 0 2 2 2 1 von Willebrand factor type C domain TSP_1 PF00090.19 KFQ93665.1 - 6.2e-06 26.3 6.2 6.2e-06 26.3 6.2 2.9 2 0 0 2 2 2 1 Thrombospondin type 1 domain Phosphodiest PF01663.22 KFQ93666.1 - 6.3e-87 292.5 0.0 8.3e-87 292.1 0.0 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.17 KFQ93666.1 - 2.6e-15 56.5 42.6 2.7e-08 34.1 14.8 3.0 3 0 0 3 3 3 2 Somatomedin B domain Endonuclease_NS PF01223.23 KFQ93666.1 - 6.1e-08 32.8 0.1 1.1e-07 32.0 0.1 1.3 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Sulfatase PF00884.23 KFQ93666.1 - 0.00028 20.4 0.0 0.02 14.3 0.0 2.3 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFQ93667.1 - 7.1e-83 279.1 0.1 1.1e-82 278.6 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.17 KFQ93667.1 - 6.7e-14 52.0 46.2 2e-08 34.5 14.3 3.0 3 0 0 3 3 3 2 Somatomedin B domain Endonuclease_NS PF01223.23 KFQ93667.1 - 4.5e-11 43.0 0.2 1.1e-10 41.7 0.2 1.7 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Metalloenzyme PF01676.18 KFQ93667.1 - 3.5e-05 23.3 0.0 5.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KFQ93667.1 - 0.0035 16.8 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 2 Sulfatase Med23 PF11573.8 KFQ93668.1 - 0 2038.2 9.0 0 2038.1 9.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 23 AKAP7_NLS PF10469.9 KFQ93669.1 - 5.2e-39 134.3 3.4 7.5e-39 133.8 3.4 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain AKAP7_RIRII_bdg PF10470.9 KFQ93669.1 - 5.6e-35 119.2 3.7 1.3e-34 118.0 3.7 1.6 1 0 0 1 1 1 1 PKA-RI-RII subunit binding domain of A-kinase anchor protein 2_5_RNA_ligase2 PF13563.6 KFQ93669.1 - 1.8e-06 27.9 0.1 3.5e-06 27.0 0.0 1.5 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily Corona_NS2A PF05213.12 KFQ93669.1 - 0.0075 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Coronavirus NS2A protein LigT_PEase PF02834.16 KFQ93669.1 - 0.028 14.6 0.4 1.6 9.0 0.0 2.8 3 1 0 3 3 3 0 LigT like Phosphoesterase MutS_V PF00488.21 KFQ93670.1 - 5.2e-52 176.6 0.1 9.9e-52 175.7 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFQ93670.1 - 5.9e-26 91.9 0.6 1.1e-25 91.0 0.6 1.4 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 KFQ93670.1 - 3.7e-13 49.6 0.0 7.5e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_14 PF13173.6 KFQ93670.1 - 0.078 13.0 0.0 0.25 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain 4_1_CTD PF05902.13 KFQ93671.1 - 9.3e-50 167.2 10.2 9.3e-50 167.2 10.2 3.4 3 0 0 3 3 3 1 4.1 protein C-terminal domain (CTD) FERM_C PF09380.10 KFQ93671.1 - 1.2e-24 86.5 0.0 2.6e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain SAB PF04382.13 KFQ93671.1 - 8.7e-23 80.1 2.1 8.7e-23 80.1 2.1 2.6 2 0 0 2 2 2 1 SAB domain FERM_M PF00373.18 KFQ93671.1 - 9.9e-20 71.1 0.1 9.9e-20 71.1 0.1 3.1 3 0 0 3 3 3 1 FERM central domain FERM_N PF09379.10 KFQ93671.1 - 1.3e-19 69.8 0.5 4.2e-19 68.3 0.3 2.0 2 0 0 2 2 2 1 FERM N-terminal domain FA PF08736.11 KFQ93671.1 - 1.5e-17 63.4 4.5 1.5e-17 63.4 4.5 2.6 2 0 0 2 2 2 1 FERM adjacent (FA) RVT_1 PF00078.27 KFQ93672.1 - 0.0015 18.0 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2371 PF10177.9 KFQ93673.1 - 3e-61 205.7 0.1 6.1e-61 204.7 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2371) Neurensin PF14927.6 KFQ93673.1 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Neurensin RbcS PF12338.8 KFQ93673.1 - 0.08 13.1 0.3 0.33 11.2 0.3 2.1 1 0 0 1 1 1 0 Ribulose-1,5-bisphosphate carboxylase small subunit She9_MDM33 PF05546.11 KFQ93673.1 - 0.082 12.7 0.0 0.34 10.7 0.0 1.9 1 1 1 2 2 2 0 She9 / Mdm33 family DUF202 PF02656.15 KFQ93673.1 - 0.1 13.0 0.1 11 6.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF63 PF01889.17 KFQ93673.1 - 0.17 12.1 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Membrane protein of unknown function DUF63 SAM_1 PF00536.30 KFQ93674.1 - 2.1e-11 44.1 0.4 5.3e-11 42.8 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFQ93674.1 - 9.6e-09 35.2 0.1 3.5e-08 33.4 0.1 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RPM2 PF08579.11 KFQ93674.1 - 0.3 11.5 0.1 0.3 11.5 0.1 2.5 3 0 0 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) MBT PF02820.18 KFQ93675.1 - 1.1e-95 314.0 5.5 1.5e-31 108.5 0.1 3.1 3 0 0 3 3 3 3 mbt repeat zf-C2HC PF01530.18 KFQ93675.1 - 0.0003 20.9 5.8 0.00072 19.7 5.8 1.7 1 0 0 1 1 1 1 Zinc finger, C2HC type Calci_bind_CcbP PF11535.8 KFQ93675.1 - 0.089 13.3 0.1 0.24 11.9 0.0 1.8 2 0 0 2 2 2 0 Calcium binding SWIRM-assoc_2 PF16496.5 KFQ93675.1 - 0.9 8.3 4.6 3.7 6.3 0.2 2.3 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal Tudor-knot PF11717.8 KFQ93675.1 - 1.1 9.2 5.4 3.7 7.5 0.1 2.9 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain SYS1 PF09801.9 KFQ93676.1 - 6.2e-07 29.7 16.7 9e-07 29.1 16.7 1.2 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network RhoGAP PF00620.27 KFQ93677.1 - 3.8e-42 143.7 1.5 3.8e-42 143.7 1.5 2.5 2 0 0 2 2 2 1 RhoGAP domain Phosducin PF02114.16 KFQ93677.1 - 0.0062 15.5 0.5 0.013 14.5 0.5 1.5 1 0 0 1 1 1 1 Phosducin FTO_CTD PF12934.7 KFQ93677.1 - 0.0085 15.9 1.6 0.02 14.7 0.5 2.1 2 0 0 2 2 2 1 FTO C-terminal domain PAPA-1 PF04795.12 KFQ93677.1 - 0.83 10.5 12.3 0.061 14.1 5.1 2.5 2 0 0 2 2 2 0 PAPA-1-like conserved region Laminin_G_1 PF00054.23 KFQ93678.1 - 5.6e-20 71.9 0.0 1.7e-18 67.1 0.0 2.1 2 0 0 2 2 2 1 Laminin G domain Laminin_G_2 PF02210.24 KFQ93678.1 - 7.5e-20 71.8 0.0 2.6e-19 70.0 0.0 1.7 2 0 0 2 2 2 1 Laminin G domain Laminin_G_3 PF13385.6 KFQ93678.1 - 0.0027 17.9 0.0 0.004 17.3 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_1 PF00054.23 KFQ93679.1 - 2e-08 34.5 0.0 3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.24 KFQ93679.1 - 0.0003 21.4 0.0 0.0005 20.6 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_I PF06008.14 KFQ93680.1 - 6e-48 163.8 18.8 6.6e-48 163.7 18.8 1.0 1 0 0 1 1 1 1 Laminin Domain I CLZ PF16526.5 KFQ93680.1 - 0.028 14.7 5.4 0.028 14.7 5.4 3.6 2 2 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ISG65-75 PF11727.8 KFQ93680.1 - 0.054 12.7 10.8 0.91 8.7 3.6 2.1 1 1 1 2 2 2 0 Invariant surface glycoprotein TINF2_N PF14973.6 KFQ93680.1 - 0.14 12.5 5.4 0.82 10.0 1.5 2.3 1 1 1 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus LPP PF04728.13 KFQ93680.1 - 0.14 12.5 0.5 0.14 12.5 0.5 3.9 2 2 2 4 4 4 0 Lipoprotein leucine-zipper TIP120 PF08623.10 KFQ93680.1 - 0.15 11.9 4.5 0.068 12.9 1.0 2.1 1 1 0 2 2 2 0 TATA-binding protein interacting (TIP20) TMF_TATA_bd PF12325.8 KFQ93680.1 - 0.17 12.1 20.7 0.074 13.3 11.1 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3484 PF11983.8 KFQ93680.1 - 0.2 12.8 1.0 3.3 8.9 0.1 2.6 2 1 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch DUF883 PF05957.13 KFQ93680.1 - 0.32 11.6 18.3 0.48 11.1 1.3 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF948 PF06103.11 KFQ93680.1 - 0.32 11.3 9.8 1.7 8.9 1.5 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1400 PF07176.11 KFQ93680.1 - 0.35 11.2 5.9 0.085 13.1 1.0 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) RNase_J_C PF17770.1 KFQ93680.1 - 0.48 11.5 4.9 0.8 10.8 0.3 3.2 1 1 3 4 4 4 0 Ribonuclease J C-terminal domain Spc7 PF08317.11 KFQ93680.1 - 0.88 8.4 24.6 0.073 11.9 15.2 2.0 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF1068 PF06364.12 KFQ93680.1 - 1.2 9.0 5.9 0.88 9.4 3.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1068) DUF334 PF03904.13 KFQ93680.1 - 1.3 8.5 7.2 2 7.9 7.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF334) ADIP PF11559.8 KFQ93680.1 - 3.3 7.8 20.0 3.4 7.7 10.4 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Spore_II_R PF09551.10 KFQ93680.1 - 3.3 8.2 7.7 9.8 6.7 0.2 3.1 2 1 2 4 4 4 0 Stage II sporulation protein R (spore_II_R) YlqD PF11068.8 KFQ93680.1 - 3.4 8.1 15.6 2.7 8.4 7.4 2.8 1 1 1 2 2 2 0 YlqD protein DUF1664 PF07889.12 KFQ93680.1 - 4.9 7.2 9.4 7.6 6.6 0.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CENP-O PF09496.10 KFQ93680.1 - 7.3 6.5 9.6 0.71 9.8 0.5 2.2 1 1 1 2 2 2 0 Cenp-O kinetochore centromere component YtxH PF12732.7 KFQ93680.1 - 7.4 7.2 11.1 3e+03 -1.2 11.0 3.1 1 1 0 1 1 1 0 YtxH-like protein Exonuc_VII_L PF02601.15 KFQ93680.1 - 7.6 6.0 18.3 4.1 6.9 9.7 2.0 1 1 1 2 2 2 0 Exonuclease VII, large subunit RRP36 PF06102.12 KFQ93680.1 - 8.5 6.3 16.4 0.51 10.3 9.4 2.0 1 1 0 2 2 2 0 rRNA biogenesis protein RRP36 Laminin_N PF00055.17 KFQ93681.1 - 1.6e-72 243.9 0.0 1.6e-72 243.9 0.0 2.6 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 KFQ93681.1 - 2.9e-50 168.2 141.3 3.2e-10 40.0 9.5 8.9 9 0 0 9 9 9 8 Laminin EGF domain Laminin_B PF00052.18 KFQ93681.1 - 4.2e-34 117.3 0.0 6e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 Laminin B (Domain IV) Aa_trans PF01490.18 KFQ93682.1 - 4e-75 253.1 25.4 4.5e-75 252.9 25.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Y_phosphatase PF00102.27 KFQ93683.1 - 6.4e-152 503.8 0.1 3.4e-86 288.6 0.1 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 KFQ93683.1 - 4.8e-25 87.7 0.5 3.9e-10 39.9 0.1 5.1 5 0 0 5 5 5 2 Fibronectin type III domain MAM PF00629.23 KFQ93683.1 - 8.6e-20 71.3 0.0 1.8e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu DSPc PF00782.20 KFQ93683.1 - 2.7e-08 33.7 1.1 0.0047 16.8 0.1 2.6 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain I-set PF07679.16 KFQ93683.1 - 5e-07 29.7 0.0 1.3e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ93683.1 - 3.6e-05 24.3 0.0 9.2e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFQ93683.1 - 7.7e-05 22.8 0.0 0.00018 21.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Y_phosphatase3 PF13350.6 KFQ93683.1 - 9.7e-05 22.4 0.0 0.061 13.3 0.0 2.5 2 0 0 2 2 2 2 Tyrosine phosphatase family Ig_2 PF13895.6 KFQ93683.1 - 0.00078 19.7 0.0 0.002 18.4 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain PTPlike_phytase PF14566.6 KFQ93683.1 - 0.0035 17.5 0.0 0.16 12.1 0.0 2.6 2 0 0 2 2 2 1 Inositol hexakisphosphate Protocadherin PF08374.11 KFQ93683.1 - 0.021 14.8 0.1 0.045 13.7 0.1 1.5 1 0 0 1 1 1 0 Protocadherin Ly49 PF08391.10 KFQ93683.1 - 0.03 14.7 0.0 0.57 10.5 0.0 2.4 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region V-set PF07686.17 KFQ93683.1 - 0.05 13.8 0.1 0.57 10.4 0.1 2.5 1 1 0 1 1 1 0 Immunoglobulin V-set domain ECSCR PF15820.5 KFQ93683.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF1310 PF07006.11 KFQ93683.1 - 0.16 12.0 0.2 14 5.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1310) CABIT PF12736.7 KFQ93684.1 - 3.1e-106 354.8 4.6 1e-52 179.2 1.8 2.1 2 0 0 2 2 2 2 Cell-cycle sustaining, positive selection, DUF1966 PF09260.11 KFQ93684.1 - 0.0023 18.1 0.1 0.0062 16.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Nop10p PF04135.12 KFQ93684.1 - 0.13 12.3 0.3 14 5.8 0.1 2.7 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family Leg1 PF05612.12 KFQ93685.1 - 3.1e-87 292.8 0.0 3.6e-87 292.6 0.0 1.0 1 0 0 1 1 1 1 Leg1 SOGA PF11365.8 KFQ93687.1 - 5.6e-63 210.1 48.4 1.7e-31 109.2 1.0 5.1 4 1 2 6 6 6 3 Protein SOGA ERM PF00769.19 KFQ93687.1 - 0.0021 17.9 6.3 0.0021 17.9 6.3 4.6 3 1 0 3 3 3 1 Ezrin/radixin/moesin family DUF2968 PF11180.8 KFQ93687.1 - 0.0033 17.1 7.3 0.0033 17.1 7.3 3.8 2 1 1 3 3 3 1 Protein of unknown function (DUF2968) TSC22 PF01166.18 KFQ93687.1 - 0.0094 16.2 0.3 0.0094 16.2 0.3 7.0 7 1 0 7 7 7 3 TSC-22/dip/bun family Halo_GVPC PF05465.13 KFQ93687.1 - 0.036 14.3 0.6 0.092 13.0 0.6 1.7 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat SlyX PF04102.12 KFQ93687.1 - 0.52 11.0 41.0 1.4 9.6 0.2 7.6 5 3 2 7 7 7 0 SlyX APG6_N PF17675.1 KFQ93687.1 - 1.5 9.4 65.2 5.1 7.6 6.2 6.2 3 1 2 5 5 5 0 Apg6 coiled-coil region YabA PF06156.13 KFQ93687.1 - 9.3 7.0 48.7 1.1 10.0 3.5 6.9 3 3 3 7 7 7 0 Initiation control protein YabA DUF4482 PF14818.6 KFQ93688.1 - 5.7e-35 121.2 15.6 5.7e-35 121.2 15.6 3.9 4 0 0 4 4 4 2 Domain of unknown function (DUF4482) WWE PF02825.20 KFQ93689.1 - 5.1e-16 59.0 4.8 6.3e-16 58.7 3.1 2.0 2 0 0 2 2 2 1 WWE domain zf-C3HC4_3 PF13920.6 KFQ93689.1 - 3.9e-07 29.8 10.6 7.3e-07 29.0 10.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ93689.1 - 1.8e-05 24.5 9.4 4.3e-05 23.3 9.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFQ93689.1 - 0.00014 21.8 9.3 0.00032 20.6 9.0 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFQ93689.1 - 0.00016 22.0 12.5 0.00028 21.2 12.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFQ93689.1 - 0.00047 19.9 12.0 0.00083 19.1 12.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFQ93689.1 - 0.0032 17.3 9.9 0.0061 16.4 9.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFQ93689.1 - 0.016 15.4 10.6 0.016 15.4 10.6 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KFQ93689.1 - 0.016 15.2 11.4 0.029 14.3 11.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_10 PF16685.5 KFQ93689.1 - 0.028 14.6 7.4 0.051 13.7 7.4 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 CENP-W PF15510.6 KFQ93691.1 - 8.4e-17 61.2 0.3 8.8e-17 61.1 0.3 1.0 1 0 0 1 1 1 1 CENP-W protein CBFD_NFYB_HMF PF00808.23 KFQ93691.1 - 0.0036 17.5 0.2 0.0045 17.2 0.2 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone UPF0020 PF01170.18 KFQ93693.1 - 2.4e-11 43.7 0.0 7e-11 42.2 0.0 1.7 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 KFQ93693.1 - 1.2e-05 24.7 0.0 2.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase N6_N4_Mtase PF01555.18 KFQ93693.1 - 0.0043 16.8 0.1 0.51 10.0 0.0 2.4 2 0 0 2 2 2 2 DNA methylase Eco57I PF07669.11 KFQ93693.1 - 0.097 13.2 0.0 0.33 11.5 0.0 1.9 1 0 0 1 1 1 0 Eco57I restriction-modification methylase Costars PF14705.6 KFQ93694.1 - 1.2e-33 115.1 0.1 1.5e-33 114.8 0.1 1.1 1 0 0 1 1 1 1 Costars DcpS_C PF11969.8 KFQ93695.1 - 7.6e-27 94.1 0.1 8.9e-27 93.8 0.1 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KFQ93695.1 - 9e-08 32.8 1.2 1.5e-07 32.1 1.2 1.4 1 1 0 1 1 1 1 HIT domain TLD PF07534.16 KFQ93696.1 - 4.1e-39 134.0 0.6 4.7e-39 133.8 0.6 1.0 1 0 0 1 1 1 1 TLD HD_3 PF13023.6 KFQ93697.1 - 3.7e-46 157.1 1.2 4.4e-46 156.8 1.2 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KFQ93697.1 - 4.7e-16 59.1 0.5 6.5e-16 58.6 0.5 1.3 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KFQ93697.1 - 0.00027 21.1 0.3 0.00046 20.4 0.3 1.4 1 0 0 1 1 1 1 HD domain DUF4259 PF14078.6 KFQ93697.1 - 0.22 12.3 2.9 0.25 12.1 2.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4259) TPD52 PF04201.15 KFQ93698.1 - 7.9e-62 207.6 5.2 1e-61 207.3 5.2 1.1 1 0 0 1 1 1 1 Tumour protein D52 family OST-HTH PF12872.7 KFQ93698.1 - 0.07 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 OST-HTH/LOTUS domain IBR PF01485.21 KFQ93699.1 - 2.7e-18 65.9 27.5 3e-09 37.0 8.6 3.0 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain LapA_dom PF06305.11 KFQ93699.1 - 0.35 10.7 1.0 0.61 9.9 1.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain zf-UDP PF14569.6 KFQ93699.1 - 8.5 6.6 22.3 8.7 6.5 0.4 3.7 1 1 2 3 3 3 0 Zinc-binding RING-finger NKAIN PF05640.14 KFQ93700.1 - 1.4e-71 240.0 5.6 1.6e-71 239.9 5.6 1.0 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein DUF1003 PF06210.11 KFQ93700.1 - 5.9 7.0 5.5 3.4 7.8 3.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1003) Asp-B-Hydro_N PF05279.11 KFQ93701.1 - 8.2e-07 29.3 2.1 8.2e-07 29.3 2.1 2.1 2 0 0 2 2 2 1 Aspartyl beta-hydroxylase N-terminal region GAGA_bind PF06217.12 KFQ93701.1 - 0.5 10.6 12.4 0.72 10.1 12.4 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family PA26 PF04636.13 KFQ93701.1 - 0.92 8.4 5.9 1.3 7.9 5.9 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) EPL1 PF10513.9 KFQ93701.1 - 3.3 8.1 14.7 5.5 7.3 14.7 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like ALMT PF11744.8 KFQ93701.1 - 5.7 5.7 8.6 7.9 5.2 8.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter CRAL_TRIO PF00650.20 KFQ93702.1 - 1.2e-34 119.4 0.0 2.3e-34 118.4 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFQ93702.1 - 1.7e-08 34.7 0.0 2.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFQ93702.1 - 2e-06 27.9 0.0 4.4e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Metallophos PF00149.28 KFQ93703.1 - 2.3e-13 51.1 0.1 3.3e-13 50.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Lipocalin PF00061.23 KFQ93704.1 - 6.2e-21 75.1 1.3 6.8e-21 75.0 1.3 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Myosin_N PF02736.19 KFQ93704.1 - 0.76 9.7 5.0 6.1 6.8 0.1 3.0 2 1 1 3 3 3 0 Myosin N-terminal SH3-like domain PKI PF02827.16 KFQ93705.1 - 7.5e-25 86.9 0.0 8e-25 86.8 0.0 1.0 1 0 0 1 1 1 1 cAMP-dependent protein kinase inhibitor Serinc PF03348.15 KFQ93707.1 - 9.6e-177 588.2 14.1 1.1e-176 588.0 14.1 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Vert_HS_TF PF06546.11 KFQ93708.1 - 8.2e-75 251.9 20.7 1.3e-74 251.3 19.8 1.8 2 0 0 2 2 2 1 Vertebrate heat shock transcription factor HSF_DNA-bind PF00447.17 KFQ93708.1 - 3.1e-25 88.6 0.7 7.1e-25 87.5 0.7 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding APG6_N PF17675.1 KFQ93708.1 - 0.029 14.9 1.0 0.068 13.7 1.0 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region HALZ PF02183.18 KFQ93708.1 - 0.037 14.3 0.3 0.091 13.0 0.3 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 KFQ93708.1 - 0.12 12.4 1.7 0.33 11.1 1.7 1.8 1 0 0 1 1 1 0 Basic region leucine zipper LMBR1 PF04791.16 KFQ93708.1 - 2 7.3 3.5 3.2 6.5 3.5 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Connexin PF00029.19 KFQ93709.1 - 2e-94 315.8 2.2 2.9e-94 315.2 2.2 1.2 1 0 0 1 1 1 1 Connexin Connexin43 PF03508.13 KFQ93709.1 - 4.6e-11 42.0 15.4 1e-10 41.0 15.4 1.6 1 0 0 1 1 1 1 Gap junction alpha-1 protein (Cx43) Connexin40_C PF16791.5 KFQ93709.1 - 7.1e-06 27.2 1.7 1.1e-05 26.6 1.7 1.3 1 0 0 1 1 1 1 Connexin 40 C-terminal domain SieB PF14163.6 KFQ93709.1 - 6 6.4 7.4 0.87 9.1 0.1 2.7 3 0 0 3 3 3 0 Super-infection exclusion protein B TEX29 PF15839.5 KFQ93709.1 - 8.5 7.1 6.9 1.5 9.5 0.2 2.6 2 1 0 2 2 2 0 Testis-expressed sequence 29 protein BROMI PF14961.6 KFQ93711.1 - 0 2092.7 18.1 0 2092.6 18.1 1.0 1 0 0 1 1 1 1 Broad-minded protein RabGAP-TBC PF00566.18 KFQ93711.1 - 0.013 15.2 6.6 0.015 15.0 4.1 2.5 2 0 0 2 2 2 0 Rab-GTPase-TBC domain UBN_AB PF14075.6 KFQ93711.1 - 0.07 12.8 2.1 2.2 8.0 0.0 2.6 2 0 0 2 2 2 0 Ubinuclein conserved middle domain Glyco_hydro_47 PF01532.20 KFQ93712.1 - 4.9e-155 516.9 0.0 5.6e-155 516.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.13 KFQ93712.1 - 0.061 12.4 0.7 0.14 11.2 0.1 1.9 3 0 0 3 3 3 0 Glycosyl Hydrolase Family 88 TBPIP PF07106.13 KFQ93712.1 - 0.11 12.4 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain MCM PF00493.23 KFQ93714.1 - 4.7e-77 258.1 0.0 8.6e-77 257.2 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFQ93714.1 - 7e-23 80.9 3.8 2.9e-22 78.9 3.8 2.0 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFQ93714.1 - 8.9e-17 61.3 2.2 8.8e-16 58.1 2.2 2.6 2 0 0 2 2 2 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KFQ93714.1 - 7.9e-09 35.2 0.1 0.00033 20.1 0.0 2.6 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFQ93714.1 - 2.1e-07 31.0 0.0 4.4e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFQ93714.1 - 0.0059 16.5 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFQ93714.1 - 0.039 14.3 0.3 0.3 11.4 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain Sigma54_activat PF00158.26 KFQ93714.1 - 0.046 13.4 0.0 5.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 KFQ93714.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 KFQ93714.1 - 0.19 11.4 0.5 0.65 9.7 0.1 2.1 2 1 0 2 2 2 0 AAA domain ASF1_hist_chap PF04729.13 KFQ93715.1 - 6.7e-72 240.5 0.1 8.3e-72 240.2 0.1 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone UPF0154 PF03672.13 KFQ93715.1 - 0.074 13.1 0.0 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0154) MFS_1 PF07690.16 KFQ93716.1 - 3.5e-18 65.7 18.1 2.7e-12 46.3 4.3 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFQ93716.1 - 1.9e-11 43.2 15.6 2.3e-09 36.3 1.0 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein Inhibitor_Mig-6 PF11555.8 KFQ93717.1 - 1.1e-14 54.2 8.9 1.1e-14 54.2 8.9 3.1 3 0 0 3 3 3 2 EGFR receptor inhibitor Mig-6 GTPase_binding PF09027.10 KFQ93717.1 - 9.2e-06 25.6 0.0 2.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 GTPase binding DJ-1_PfpI PF01965.24 KFQ93718.1 - 2.3e-52 177.1 0.0 2.6e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KFQ93718.1 - 0.00031 20.5 0.0 0.026 14.2 0.0 2.1 1 1 1 2 2 2 2 ThiJ/PfpI family-like GATase_3 PF07685.14 KFQ93718.1 - 0.026 14.1 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain TNFR_c6 PF00020.18 KFQ93719.1 - 5.1e-08 33.2 20.4 2.5e-05 24.6 0.8 3.2 3 0 0 3 3 3 3 TNFR/NGFR cysteine-rich region Urotensin_II PF02083.15 KFQ93720.1 - 1.4e-06 27.6 1.0 2.6e-06 26.7 1.0 1.5 1 0 0 1 1 1 1 Urotensin II Synaptobrevin PF00957.21 KFQ93721.1 - 1e-34 118.2 4.1 1.1e-34 118.0 4.1 1.0 1 0 0 1 1 1 1 Synaptobrevin MCU PF04678.13 KFQ93721.1 - 0.0099 16.0 0.2 0.011 15.8 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial calcium uniporter DUF3619 PF12279.8 KFQ93721.1 - 0.066 13.5 0.5 0.084 13.2 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3619) ASFV_J13L PF05568.11 KFQ93721.1 - 4.7 6.9 7.6 7.7 6.2 7.2 1.5 1 1 0 1 1 1 0 African swine fever virus J13L protein CG-1 PF03859.16 KFQ93722.1 - 8.6e-34 115.8 1.1 2.6e-33 114.3 1.1 1.9 1 0 0 1 1 1 1 CG-1 domain TIG PF01833.24 KFQ93722.1 - 1.1e-10 41.4 1.3 3e-10 40.0 0.1 2.5 2 0 0 2 2 2 1 IPT/TIG domain Ank_2 PF12796.7 KFQ93722.1 - 2.2e-09 37.8 0.1 5.8e-05 23.6 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFQ93722.1 - 4.5e-05 23.6 0.7 0.53 10.7 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ93722.1 - 0.00026 21.2 0.5 0.94 10.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat IQ PF00612.27 KFQ93722.1 - 0.0016 18.1 18.7 0.8 9.7 0.3 5.5 5 0 0 5 5 5 3 IQ calmodulin-binding motif Ank_4 PF13637.6 KFQ93722.1 - 0.0032 18.0 1.2 0.31 11.7 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 KFQ93722.1 - 0.012 16.1 0.3 3.4 8.3 0.1 2.8 2 0 0 2 2 2 0 Ankyrin repeat DUF3395 PF11875.8 KFQ93724.1 - 1.8e-46 157.9 0.3 1.8e-46 157.9 0.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 KFQ93724.1 - 1.8e-17 63.2 1.7 3.8e-17 62.1 0.5 2.1 2 0 0 2 2 2 1 DnaJ domain DUF4736 PF15883.5 KFQ93724.1 - 0.09 12.5 1.4 0.17 11.6 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) GDA1_CD39 PF01150.17 KFQ93724.1 - 0.13 10.8 0.1 0.2 10.2 0.1 1.1 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family PHD PF00628.29 KFQ93725.1 - 3.4e-08 33.3 8.2 5.9e-08 32.5 8.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KFQ93725.1 - 3.8e-06 26.4 5.3 6.9e-06 25.5 5.3 1.4 1 0 0 1 1 1 1 PHD-finger zf-C4H2 PF10146.9 KFQ93725.1 - 0.0036 17.7 0.1 0.0055 17.0 0.1 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein zf-HC5HC2H PF13771.6 KFQ93725.1 - 0.014 15.6 1.1 0.031 14.5 1.1 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain C1_1 PF00130.22 KFQ93725.1 - 0.017 15.0 2.0 0.017 15.0 2.0 1.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_9 PF13901.6 KFQ93725.1 - 0.77 9.7 6.8 1.4 8.9 6.8 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Kelch_1 PF01344.25 KFQ93726.1 - 1.1e-38 130.6 23.2 1.5e-11 43.7 2.3 8.2 7 2 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 KFQ93726.1 - 3.4e-33 112.8 5.7 1.7e-10 40.8 0.0 6.5 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KFQ93726.1 - 7.6e-19 66.9 11.6 9.5e-08 31.7 0.1 6.4 6 1 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 KFQ93726.1 - 1.3e-18 66.8 11.2 5.9e-06 26.4 0.3 5.5 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.6 KFQ93726.1 - 1.6e-15 56.8 7.5 0.00017 21.6 0.3 6.5 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KFQ93726.1 - 4.1e-05 23.5 11.8 0.099 12.7 0.2 4.4 5 0 0 5 5 5 2 Kelch motif PQQ_3 PF13570.6 KFQ93726.1 - 0.0011 19.4 3.3 0.8 10.3 0.1 3.7 3 0 0 3 3 3 1 PQQ-like domain DUF1668 PF07893.13 KFQ93726.1 - 0.049 13.0 0.1 1.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1668) zf-H2C2_2 PF13465.6 KFQ93727.1 - 1.4e-53 177.1 80.9 1.4e-09 37.9 1.9 11.1 11 0 0 11 11 11 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ93727.1 - 1.6e-36 122.7 82.1 4e-06 27.0 1.9 10.3 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ93727.1 - 7.1e-30 101.1 80.3 0.0013 19.4 1.6 10.4 10 0 0 10 10 10 9 C2H2-type zinc finger zf-met PF12874.7 KFQ93727.1 - 6.9e-07 29.4 61.6 0.043 14.2 0.9 9.7 10 0 0 10 10 9 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFQ93727.1 - 1.1e-06 28.7 48.2 0.0033 17.7 0.4 9.6 10 0 0 10 10 10 4 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFQ93727.1 - 3.2e-06 26.8 4.8 7.8e-05 22.3 0.6 8.4 9 0 0 9 9 9 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFQ93727.1 - 3.6e-06 26.8 77.4 6.2e-05 22.9 2.2 9.6 10 0 0 10 10 9 5 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFQ93727.1 - 0.0011 18.6 4.6 0.0073 16.0 0.6 9.1 9 1 0 9 9 9 4 C2H2-type zinc-finger domain GAGA PF09237.11 KFQ93727.1 - 0.0019 17.9 3.9 0.03 14.1 0.3 6.0 2 2 4 7 7 7 3 GAGA factor zf-C2H2_8 PF15909.5 KFQ93727.1 - 0.0024 18.1 45.0 0.27 11.6 2.6 5.5 1 1 4 5 5 5 3 C2H2-type zinc ribbon zinc_ribbon_15 PF17032.5 KFQ93727.1 - 0.018 15.7 38.4 0.29 11.9 1.1 5.4 2 1 3 5 5 5 0 zinc-ribbon family DUF2387 PF09526.10 KFQ93727.1 - 0.065 13.4 0.3 0.065 13.4 0.3 3.9 4 1 1 5 5 5 0 Probable metal-binding protein (DUF2387) Zn-ribbon_8 PF09723.10 KFQ93727.1 - 0.092 12.9 52.1 1.5 9.0 1.8 8.2 6 2 2 8 8 7 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 KFQ93727.1 - 0.13 12.6 60.2 0.079 13.3 7.9 8.5 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 KFQ93727.1 - 0.14 12.8 39.2 0.9 10.2 0.8 7.1 1 1 5 6 6 6 0 Zinc finger C2H2-type, 3 repeats DUF4226 PF10774.9 KFQ93727.1 - 0.16 12.3 0.0 18 5.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) zf-MYST PF17772.1 KFQ93727.1 - 0.51 10.0 27.2 1.4 8.5 1.0 7.1 6 2 2 8 8 8 0 MYST family zinc finger domain DUF3268 PF11672.8 KFQ93727.1 - 0.77 10.1 27.4 0.6 10.5 0.4 4.9 3 2 4 7 7 7 0 zinc-finger-containing domain ANF_receptor PF01094.28 KFQ93728.1 - 2e-46 158.8 0.0 2.7e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.14 KFQ93728.1 - 8.4e-14 51.3 10.9 8.4e-14 51.3 10.9 1.9 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR 7tm_3 PF00003.22 KFQ93728.1 - 4.3e-12 46.3 9.2 7.7e-12 45.5 9.2 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 KFQ93728.1 - 0.003 17.3 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein Sp38 PF07354.12 KFQ93728.1 - 3.3 7.1 10.3 0.84 9.0 6.4 1.8 2 0 0 2 2 2 0 Zona-pellucida-binding protein (Sp38) Ephrin_rec_like PF07699.13 KFQ93728.1 - 8.2 6.3 12.3 0.16 11.8 4.7 2.0 2 0 0 2 2 2 0 Putative ephrin-receptor like CLP1_P PF16575.5 KFQ93729.1 - 6e-15 55.5 0.0 9.1e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 KFQ93729.1 - 0.061 13.7 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 4HBT PF03061.22 KFQ93731.1 - 1e-32 112.3 1.4 6.1e-16 58.6 0.1 2.2 2 0 0 2 2 2 2 Thioesterase superfamily tRNA_anti-codon PF01336.25 KFQ93731.1 - 0.00027 20.9 0.0 0.0027 17.7 0.0 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Ribosomal_L22e PF01776.17 KFQ93732.1 - 5.3e-41 139.4 2.3 6.2e-41 139.2 2.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family AJAP1_PANP_C PF15298.6 KFQ93734.1 - 1.1e-48 166.0 0.8 1.2e-48 165.9 0.8 1.0 1 0 0 1 1 1 1 AJAP1/PANP C-terminus Stomagen PF16851.5 KFQ93734.1 - 0.0023 17.9 0.1 0.0038 17.2 0.1 1.3 1 0 0 1 1 1 1 Stomagen UPF0688 PF15772.5 KFQ93735.1 - 7.4e-55 186.7 11.7 8.7e-55 186.5 11.7 1.0 1 0 0 1 1 1 1 UPF0688 family YjzC PF14168.6 KFQ93735.1 - 0.14 12.6 1.2 0.26 11.7 1.2 1.4 1 0 0 1 1 1 0 YjzC-like protein Plasmodium_Vir PF05795.11 KFQ93735.1 - 2.3 7.6 8.1 2.6 7.4 8.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DFF40 PF09230.10 KFQ93736.1 - 6.3e-96 320.4 4.2 7.4e-96 320.1 4.2 1.0 1 0 0 1 1 1 1 DNA fragmentation factor 40 kDa IP_trans PF02121.18 KFQ93736.1 - 0.026 14.1 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol transfer protein CLASP_N PF12348.8 KFQ93737.1 - 0.0081 15.7 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 CLASP N terminal ATP-synt_E_2 PF08112.11 KFQ93737.1 - 0.036 14.3 0.3 0.14 12.5 0.3 1.9 1 0 0 1 1 1 0 ATP synthase epsilon subunit EAV_GS PF01309.18 KFQ93737.1 - 0.14 11.7 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 Equine arteritis virus small envelope glycoprotein UVR PF02151.19 KFQ93737.1 - 0.19 11.5 22.2 0.071 12.9 3.2 3.1 3 0 0 3 3 3 0 UvrB/uvrC motif zf_UBZ PF18439.1 KFQ93737.1 - 0.22 11.2 9.7 1 9.0 0.6 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger B3_4 PF03483.17 KFQ93738.1 - 9.9e-11 41.6 0.0 1.7e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain SpoVG PF04026.12 KFQ93738.1 - 0.089 13.0 0.0 15 5.9 0.0 2.4 2 0 0 2 2 2 0 SpoVG MPS2 PF17060.5 KFQ93739.1 - 0.019 14.3 15.5 0.017 14.4 14.6 1.3 1 1 0 1 1 1 0 Monopolar spindle protein 2 DUF2922 PF11148.8 KFQ93739.1 - 0.074 12.8 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) RRT14 PF17075.5 KFQ93739.1 - 0.17 12.0 17.9 0.16 12.1 16.0 1.7 1 1 1 2 2 2 0 Regular of rDNA transcription protein 14 MAD PF05557.13 KFQ93739.1 - 0.23 9.8 27.2 0.56 8.5 26.6 1.8 1 1 0 1 1 1 0 Mitotic checkpoint protein STATa_Ig PF18214.1 KFQ93739.1 - 0.36 10.9 3.4 0.38 10.8 0.4 2.4 1 1 1 2 2 2 0 STATa Immunoglobulin-like domain USP8_interact PF08941.10 KFQ93739.1 - 0.53 10.1 13.5 0.21 11.4 3.3 2.3 2 0 0 2 2 2 0 USP8 interacting SOGA PF11365.8 KFQ93739.1 - 0.6 11.3 20.8 0.19 12.8 14.7 2.4 2 1 0 2 2 2 0 Protein SOGA ATG16 PF08614.11 KFQ93739.1 - 0.82 9.9 27.5 0.039 14.2 18.3 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FAST_2 PF08368.12 KFQ93739.1 - 0.92 10.3 5.3 2 9.3 0.0 2.9 1 1 2 3 3 3 0 FAST kinase-like protein, subdomain 2 TMF_DNA_bd PF12329.8 KFQ93739.1 - 1.2 9.1 20.6 1.5 8.9 4.1 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Uso1_p115_C PF04871.13 KFQ93739.1 - 1.5 9.2 21.5 4.6 7.6 11.6 2.4 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Atg14 PF10186.9 KFQ93739.1 - 2.5 7.1 19.4 3.3 6.7 19.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.14 KFQ93739.1 - 4.3 7.1 21.5 1.1 9.0 10.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) P53 PF00870.18 KFQ93740.1 - 1.9e-64 217.0 0.0 3.3e-64 216.3 0.0 1.4 1 0 0 1 1 1 1 P53 DNA-binding domain P53_tetramer PF07710.11 KFQ93740.1 - 3.6e-18 64.6 0.8 7.8e-18 63.5 0.8 1.6 1 0 0 1 1 1 1 P53 tetramerisation motif SAM_2 PF07647.17 KFQ93740.1 - 2.5e-08 33.9 0.0 4.8e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFQ93740.1 - 0.0026 18.1 0.0 0.0049 17.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) ANAPC4_WD40 PF12894.7 KFQ93741.1 - 3.4e-12 46.5 0.6 0.0021 18.3 0.0 6.6 2 2 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFQ93741.1 - 7.8e-11 42.4 4.4 0.0047 17.7 0.0 7.6 7 1 0 7 7 7 2 WD domain, G-beta repeat eIF2A PF08662.11 KFQ93741.1 - 1.4e-07 31.6 0.1 1.6 8.6 0.0 4.4 2 2 2 4 4 4 4 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KFQ93741.1 - 0.026 12.5 4.1 0.81 7.6 0.0 3.0 2 1 1 4 4 4 0 IKI3 family PD40 PF07676.12 KFQ93741.1 - 0.031 14.2 0.7 38 4.4 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat hSac2 PF12456.8 KFQ93742.1 - 1.6e-19 69.7 0.0 2.5e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Inositol phosphatase zf-C2H2 PF00096.26 KFQ93743.1 - 5.3e-49 162.0 83.5 5.1e-07 29.8 1.4 10.4 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ93743.1 - 2.2e-32 108.9 76.7 0.00082 20.0 0.6 10.5 10 0 0 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFQ93743.1 - 2.4e-27 94.1 80.0 2.9e-08 33.8 1.2 11.7 13 0 0 13 13 13 6 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFQ93743.1 - 2.7e-12 46.6 55.2 0.061 13.6 0.2 10.4 10 0 0 10 10 10 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFQ93743.1 - 9.6e-09 35.0 67.2 0.058 13.4 0.2 10.2 10 0 0 10 10 10 8 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFQ93743.1 - 1.9e-08 33.9 53.8 0.058 13.2 2.8 9.3 10 0 0 10 10 10 6 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KFQ93743.1 - 1.4e-07 31.2 56.7 4.3e-05 23.2 2.4 8.7 9 1 0 9 9 8 5 C2H2-type zinc-finger domain zf-BED PF02892.15 KFQ93743.1 - 0.00064 19.7 0.5 0.00064 19.7 0.5 7.9 3 3 5 8 8 8 3 BED zinc finger zf-met PF12874.7 KFQ93743.1 - 0.0029 17.9 50.8 0.36 11.3 0.4 9.5 9 0 0 9 9 9 3 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFQ93743.1 - 0.0059 16.9 40.9 0.21 11.9 8.3 5.3 2 1 3 5 5 5 3 C2H2-type zinc ribbon GAGA PF09237.11 KFQ93743.1 - 0.061 13.1 20.2 2 8.3 0.4 5.8 3 1 2 5 5 5 0 GAGA factor zinc_ribbon_15 PF17032.5 KFQ93743.1 - 0.15 12.8 39.5 0.2 12.4 0.2 6.5 3 1 2 7 7 7 0 zinc-ribbon family Ribosomal_L31 PF01197.18 KFQ93743.1 - 0.38 11.0 9.5 5.5 7.3 1.2 4.7 3 1 1 4 4 4 0 Ribosomal protein L31 TPR_2 PF07719.17 KFQ93745.1 - 1e-22 78.3 12.5 0.011 15.8 0.0 9.9 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ93745.1 - 5e-20 70.4 21.3 0.018 14.9 0.0 9.7 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_9 PF13371.6 KFQ93745.1 - 1.8e-12 47.2 6.0 8.5e-05 22.6 0.0 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ93745.1 - 1.4e-11 44.8 14.2 0.12 12.9 0.1 6.8 6 2 1 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ93745.1 - 7e-10 39.1 15.9 0.25 11.6 0.0 8.2 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ93745.1 - 1.9e-09 38.0 6.4 0.045 14.4 0.0 6.4 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ93745.1 - 8.6e-09 34.9 16.1 0.25 11.6 0.1 9.4 11 0 0 11 11 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ93745.1 - 1.2e-08 35.1 20.4 0.14 12.4 0.5 6.5 6 0 0 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KFQ93745.1 - 2.7e-08 33.4 7.1 0.48 10.1 0.0 7.2 7 1 1 8 8 8 3 TPR repeat TPR_6 PF13174.6 KFQ93745.1 - 9.4e-07 29.1 8.3 0.12 13.1 0.0 6.9 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 KFQ93745.1 - 2.1e-06 27.2 3.9 0.0072 15.6 0.1 4.7 2 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ93745.1 - 2.7e-06 27.4 9.9 0.062 13.7 0.0 7.4 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_20 PF14561.6 KFQ93745.1 - 5.5e-06 26.6 12.1 0.1 12.9 0.1 5.6 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ93745.1 - 2.2e-05 24.9 11.7 0.53 11.2 0.3 7.3 6 3 3 9 9 9 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ93745.1 - 0.0002 21.1 8.5 5.4 7.0 0.0 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KFQ93745.1 - 0.00037 20.5 7.4 0.29 11.2 0.7 4.8 2 1 1 3 3 3 1 Putative TPR-like repeat TPR_4 PF07721.14 KFQ93745.1 - 0.019 15.6 0.7 0.49 11.2 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ93745.1 - 0.26 11.4 5.5 17 5.7 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFQ93745.1 - 0.42 10.7 8.1 23 5.1 0.3 4.7 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat SMBP PF16785.5 KFQ93745.1 - 0.46 10.7 3.8 2.9 8.2 0.0 3.0 3 0 0 3 3 2 0 Small metal-binding protein HLH PF00010.26 KFQ93746.1 - 7.2e-16 57.9 2.4 1.1e-15 57.3 2.4 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 KFQ93746.1 - 2.5e-07 30.8 0.9 4.1e-07 30.1 0.9 1.4 1 0 0 1 1 1 1 Hairy Orange RunxI PF08504.11 KFQ93746.1 - 0.0049 17.5 0.7 0.0092 16.7 0.4 1.5 1 1 0 1 1 1 1 Runx inhibition domain HLH PF00010.26 KFQ93747.1 - 3.8e-15 55.6 2.1 6.4e-15 54.9 2.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 KFQ93747.1 - 0.00022 21.4 0.1 0.00034 20.7 0.1 1.3 1 0 0 1 1 1 1 Hairy Orange HLH PF00010.26 KFQ93748.1 - 8.2e-16 57.7 3.4 1.3e-15 57.0 3.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 KFQ93748.1 - 1e-09 38.4 0.5 1.6e-09 37.8 0.5 1.3 1 0 0 1 1 1 1 Hairy Orange Fumble PF03630.14 KFQ93749.1 - 1.9e-128 428.3 3.3 2.4e-128 428.0 3.3 1.1 1 0 0 1 1 1 1 Fumble DUF89 PF01937.19 KFQ93749.1 - 1.4e-56 192.0 0.0 2.1e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 vATP-synt_E PF01991.18 KFQ93749.1 - 0.069 12.6 0.0 0.2 11.0 0.0 1.7 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Lig_chan PF00060.26 KFQ93750.1 - 3.1e-40 137.4 0.3 4.3e-40 137.0 0.3 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFQ93750.1 - 2.8e-37 127.4 0.0 5.4e-37 126.5 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFQ93750.1 - 1.8e-19 70.1 0.0 2.6e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Pex2_Pex12 PF04757.14 KFQ93751.1 - 1.2e-32 113.4 2.7 1.4e-32 113.1 2.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 KFQ93751.1 - 4e-09 36.7 15.7 8e-09 35.7 15.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFQ93751.1 - 7.9e-09 35.2 12.7 1.3e-08 34.5 12.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFQ93751.1 - 6.8e-08 32.3 11.3 1.1e-07 31.5 11.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFQ93751.1 - 7e-08 32.2 13.8 1.5e-07 31.2 13.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFQ93751.1 - 1.2e-06 28.4 9.6 1.5e-06 28.1 7.5 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFQ93751.1 - 1.8e-06 27.7 13.5 3.6e-06 26.7 13.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFQ93751.1 - 2.3e-05 24.6 11.2 6.7e-05 23.1 11.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFQ93751.1 - 6.1e-05 22.9 13.0 0.00012 22.0 13.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DUF3290 PF11694.8 KFQ93751.1 - 0.0097 15.9 0.2 0.019 14.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3290) zf-C3HC4_4 PF15227.6 KFQ93751.1 - 0.0097 16.0 11.7 0.035 14.2 11.8 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KFQ93751.1 - 0.029 14.2 3.9 0.055 13.3 3.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein TMCCDC2 PF15844.5 KFQ93751.1 - 0.048 13.6 1.6 0.36 10.7 0.1 2.5 3 0 0 3 3 3 0 Transmembrane and coiled-coil domain-containing protein 2 zf-RING_4 PF14570.6 KFQ93751.1 - 0.05 13.4 9.4 0.11 12.3 9.4 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KFQ93751.1 - 0.13 12.3 5.9 0.3 11.2 5.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KFQ93751.1 - 0.18 11.5 4.9 0.49 10.2 3.0 2.6 2 1 0 2 2 2 0 RING-like zinc finger Rer1 PF03248.13 KFQ93752.1 - 7.2e-78 260.2 8.2 8.2e-78 260.0 8.2 1.0 1 0 0 1 1 1 1 Rer1 family Bestrophin PF01062.21 KFQ93752.1 - 0.013 14.9 0.2 0.024 14.0 0.2 1.4 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel DUF2208 PF09973.9 KFQ93752.1 - 0.84 9.2 8.4 0.14 11.8 0.6 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Pkinase PF00069.25 KFQ93754.1 - 4.5e-64 216.3 0.0 5.9e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ93754.1 - 2.6e-33 115.4 0.0 4.2e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.24 KFQ93754.1 - 8.7e-15 54.4 0.1 2.1e-14 53.2 0.1 1.7 1 0 0 1 1 1 1 PB1 domain C1_1 PF00130.22 KFQ93754.1 - 1.2e-14 53.9 6.7 2.5e-14 52.9 6.7 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KFQ93754.1 - 1e-05 26.1 1.6 2.5e-05 24.9 1.6 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFQ93754.1 - 3.6e-05 23.2 0.0 6.7e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFQ93754.1 - 0.022 13.7 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KFQ93754.1 - 0.023 14.1 0.0 0.061 12.7 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family C1_2 PF03107.16 KFQ93754.1 - 0.034 14.5 2.5 0.079 13.3 2.5 1.6 1 0 0 1 1 1 0 C1 domain FTA2 PF13095.6 KFQ93754.1 - 0.04 13.5 0.1 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFQ93754.1 - 0.054 13.4 0.1 0.24 11.3 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DZR PF12773.7 KFQ93754.1 - 0.41 10.7 2.2 1.2 9.3 2.2 1.8 1 0 0 1 1 1 0 Double zinc ribbon Neur_chan_LBD PF02931.23 KFQ93755.1 - 1.2e-48 165.4 0.1 2e-48 164.7 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFQ93755.1 - 1.3e-33 117.0 6.7 1e-30 107.5 2.5 2.4 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF1686 PF07937.11 KFQ93755.1 - 0.077 12.9 0.8 0.12 12.2 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1686) Herpes_glycoH_C PF17488.2 KFQ93755.1 - 0.09 12.6 0.2 7.9 6.3 0.4 2.3 2 0 0 2 2 2 0 Herpesvirus glycoprotein H C-terminal domain ASH PF15780.5 KFQ93756.1 - 1.1e-06 28.7 0.1 0.21 11.8 0.0 3.5 2 2 1 3 3 3 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 KFQ93756.1 - 5e-06 26.6 0.1 0.1 12.7 0.0 2.7 3 0 0 3 3 3 2 Flagellar-associated PapD-like Motile_Sperm PF00635.26 KFQ93756.1 - 0.0031 17.4 0.1 4.8 7.1 0.0 3.2 3 0 0 3 3 3 2 MSP (Major sperm protein) domain TMEM131_like PF12371.8 KFQ93756.1 - 0.0034 17.6 0.0 3 8.2 0.0 3.4 3 0 0 3 3 3 1 Transmembrane protein 131-like TMEM52 PF14979.6 KFQ93758.1 - 1.1e-29 103.3 3.2 1.2e-29 103.2 3.2 1.0 1 0 0 1 1 1 1 Transmembrane 52 Comm PF15957.5 KFQ93758.1 - 0.15 12.4 0.9 0.17 12.2 0.9 1.1 1 0 0 1 1 1 0 Commissureless Corona_S2 PF01601.16 KFQ93758.1 - 0.92 7.9 3.8 0.98 7.8 3.8 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein NAD_kinase PF01513.21 KFQ93759.1 - 6.4e-66 222.5 0.1 7.8e-66 222.2 0.1 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KFQ93759.1 - 0.045 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Guanylate_cyc PF00211.20 KFQ93760.1 - 0.093 12.3 0.2 0.31 10.7 0.1 1.8 1 1 1 2 2 2 0 Adenylate and Guanylate cyclase catalytic domain TPT PF03151.16 KFQ93761.1 - 1.2e-91 307.1 23.6 1.5e-91 306.8 23.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFQ93761.1 - 8.3e-12 45.4 29.1 6.5e-06 26.4 12.5 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KFQ93761.1 - 9e-08 31.7 24.7 1.2e-07 31.2 24.7 1.1 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KFQ93761.1 - 0.0035 16.6 8.6 0.0035 16.6 8.6 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter Pkinase PF00069.25 KFQ93762.1 - 1.3e-65 221.4 0.0 1.3e-65 221.4 0.0 2.0 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ93762.1 - 2.9e-30 105.4 0.2 9.8e-30 103.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ93762.1 - 7.8e-06 25.4 0.2 0.00094 18.6 0.0 2.5 1 1 0 2 2 2 2 Kinase-like Peptidase_M10 PF00413.24 KFQ93763.1 - 1.5e-38 132.1 0.2 2.1e-38 131.7 0.2 1.2 1 0 0 1 1 1 1 Matrixin ShK PF01549.24 KFQ93763.1 - 6.8e-09 36.1 8.3 1.3e-08 35.2 8.3 1.5 1 0 0 1 1 1 1 ShK domain-like Ig_2 PF13895.6 KFQ93763.1 - 2.3e-05 24.7 0.1 3.9e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFQ93763.1 - 6.5e-05 23.5 0.1 0.00012 22.6 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain DUF4953 PF16313.5 KFQ93763.1 - 0.003 16.8 0.5 0.0044 16.3 0.5 1.2 1 0 0 1 1 1 1 Met-zincin Reprolysin_4 PF13583.6 KFQ93763.1 - 0.0044 16.7 0.1 0.0068 16.1 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like V-set PF07686.17 KFQ93763.1 - 0.014 15.6 0.2 0.32 11.2 0.0 2.3 1 1 1 2 2 2 0 Immunoglobulin V-set domain Reprolysin_3 PF13582.6 KFQ93763.1 - 0.016 15.7 0.8 0.027 15.0 0.8 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like I-set PF07679.16 KFQ93763.1 - 0.02 14.9 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain Reprolysin_5 PF13688.6 KFQ93763.1 - 0.04 14.1 1.5 0.19 11.8 1.7 1.8 1 1 1 2 2 2 0 Metallo-peptidase family M12 Peptidase_M57 PF12388.8 KFQ93763.1 - 0.069 12.7 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M54 PF07998.11 KFQ93763.1 - 0.08 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M54 Astacin PF01400.24 KFQ93763.1 - 0.23 11.1 4.4 0.61 9.7 2.1 2.7 3 1 1 4 4 4 0 Astacin (Peptidase family M12A) MIB_HERC2 PF06701.13 KFQ93764.1 - 3.6e-49 164.9 26.1 6.8e-25 87.1 5.3 3.8 3 0 0 3 3 3 2 Mib_herc2 Ank_2 PF12796.7 KFQ93764.1 - 6.5e-45 151.6 19.7 3.9e-13 49.8 1.0 5.8 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) SH3_15 PF18346.1 KFQ93764.1 - 6.1e-43 145.0 16.3 7.2e-24 83.9 0.4 4.2 4 0 0 4 4 4 2 Mind bomb SH3 repeat domain Ank_5 PF13857.6 KFQ93764.1 - 3.6e-40 135.5 8.4 4.5e-10 39.6 0.1 6.2 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KFQ93764.1 - 6.5e-36 121.2 4.1 2.2e-07 31.0 0.1 8.1 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 KFQ93764.1 - 1.3e-35 121.3 6.2 6.8e-10 39.3 0.1 7.2 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ93764.1 - 2.7e-28 94.9 6.9 0.00053 20.2 0.1 9.3 10 0 0 10 10 10 6 Ankyrin repeat zf-C3HC4_3 PF13920.6 KFQ93764.1 - 2.1e-10 40.3 27.4 6.5e-07 29.1 8.6 3.7 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) ZZ PF00569.17 KFQ93764.1 - 1.6e-08 34.2 11.1 1.6e-08 34.2 11.1 3.1 3 1 0 3 3 3 1 Zinc finger, ZZ type NfeD PF01957.18 KFQ93764.1 - 8.2 6.9 13.3 2.5 8.6 0.1 3.2 3 1 1 4 4 4 0 NfeD-like C-terminal, partner-binding DUF4407 PF14362.6 KFQ93765.1 - 0.56 9.5 15.8 0.74 9.1 15.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) JIP_LZII PF16471.5 KFQ93765.1 - 2.9 8.1 18.4 0.062 13.5 2.5 3.6 2 2 2 4 4 4 0 JNK-interacting protein leucine zipper II DUF3584 PF12128.8 KFQ93765.1 - 3.7 4.9 29.1 5.2 4.5 29.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Ssu72 PF04722.13 KFQ93767.1 - 4.5e-78 261.2 0.1 5e-78 261.0 0.1 1.0 1 0 0 1 1 1 1 Ssu72-like protein TMEM240 PF15207.6 KFQ93768.1 - 1.2e-75 253.0 1.8 1.5e-75 252.8 1.8 1.0 1 0 0 1 1 1 1 TMEM240 family VWA PF00092.28 KFQ93769.1 - 4.7e-35 121.4 0.0 7.3e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain fn3 PF00041.21 KFQ93769.1 - 1.1e-22 80.2 0.7 8.4e-11 42.1 0.1 2.3 2 0 0 2 2 2 2 Fibronectin type III domain VWA_2 PF13519.6 KFQ93769.1 - 1.1e-14 54.9 0.0 3.1e-14 53.5 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain Pur_ac_phosph_N PF16656.5 KFQ93769.1 - 1.5e-06 28.7 0.6 0.013 16.0 0.1 3.1 2 1 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFQ93769.1 - 1.5e-05 25.2 0.0 0.014 15.7 0.0 2.3 2 0 0 2 2 2 2 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 KFQ93769.1 - 0.012 16.0 0.0 0.57 10.6 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) Big_5 PF13205.6 KFQ93769.1 - 0.023 15.4 0.7 3.6 8.3 0.0 3.6 3 1 2 5 5 5 0 Bacterial Ig-like domain VWA_CoxE PF05762.14 KFQ93769.1 - 0.057 12.8 0.2 0.91 8.9 0.2 2.4 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein DJ-1_PfpI PF01965.24 KFQ93769.1 - 0.059 13.2 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family DUF1410 PF07198.11 KFQ93769.1 - 0.11 13.1 0.2 6.7 7.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1410) DUF2852 PF11014.8 KFQ93770.1 - 0.23 11.6 2.5 0.19 11.9 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) FtsX PF02687.21 KFQ93770.1 - 0.62 10.6 9.3 0.94 10.0 9.3 1.4 1 0 0 1 1 1 0 FtsX-like permease family Ribosomal_L20 PF00453.18 KFQ93771.1 - 4.4e-32 110.4 0.6 6.1e-32 109.9 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L20 Cyclin_N PF00134.23 KFQ93772.1 - 2.1e-14 53.3 1.2 2.6e-08 33.7 0.1 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFQ93772.1 - 7.1e-07 29.3 0.1 7.1e-07 29.3 0.1 2.2 3 0 0 3 3 3 1 Cyclin, C-terminal domain TFIIB PF00382.19 KFQ93772.1 - 0.00034 20.6 0.5 0.28 11.3 0.1 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 KFQ93772.1 - 0.0027 18.1 0.0 0.0073 16.7 0.0 1.9 2 0 0 2 2 2 1 Cyclin C-terminal domain DUF936 PF06075.12 KFQ93772.1 - 4.2 6.2 27.1 5.5 5.8 27.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) adh_short PF00106.25 KFQ93773.1 - 2.8e-22 79.1 0.6 3.7e-22 78.7 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFQ93773.1 - 1e-20 74.3 0.1 1.3e-20 74.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFQ93773.1 - 0.0029 17.6 0.3 0.0053 16.7 0.1 1.4 1 1 0 1 1 1 1 KR domain DUF1713 PF08213.11 KFQ93774.1 - 1.1e-10 41.2 20.2 1.1e-10 41.2 20.2 2.2 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) V-set PF07686.17 KFQ93775.1 - 3.8e-27 94.6 0.2 1.2e-15 57.7 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.25 KFQ93775.1 - 1.5e-09 37.9 1.1 0.0038 17.4 0.1 3.7 2 2 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFQ93775.1 - 4.2e-08 33.1 0.0 0.0083 16.2 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ93775.1 - 1.2e-07 32.2 0.7 0.015 15.9 0.1 3.5 2 2 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFQ93775.1 - 0.0014 18.9 0.2 0.37 11.2 0.0 2.8 2 0 0 2 2 2 1 Immunoglobulin domain Stevor PF17410.2 KFQ93775.1 - 0.002 17.7 0.1 0.0035 16.9 0.1 1.3 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame Izumo-Ig PF16706.5 KFQ93775.1 - 0.0036 17.3 0.0 2.3 8.3 0.0 2.5 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFQ93775.1 - 0.0075 15.8 0.0 3.3 7.3 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain V-set_CD47 PF08204.11 KFQ93775.1 - 0.03 14.3 0.1 0.8 9.7 0.0 2.4 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain DUF4064 PF13273.6 KFQ93775.1 - 0.034 14.4 0.1 0.061 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Receptor_2B4 PF11465.8 KFQ93775.1 - 0.035 14.3 2.1 5.2 7.3 0.1 3.2 4 1 0 4 4 3 0 Natural killer cell receptor 2B4 EphA2_TM PF14575.6 KFQ93775.1 - 0.13 13.1 0.0 0.34 11.8 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF347 PF03988.12 KFQ93775.1 - 0.16 12.2 0.8 0.29 11.4 0.8 1.4 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) NOGCT PF08155.11 KFQ93775.1 - 0.17 11.9 0.9 53 3.9 0.0 3.7 3 0 0 3 3 3 0 NOGCT (NUC087) domain FixQ PF05545.11 KFQ93775.1 - 0.18 11.8 0.7 0.34 10.9 0.7 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Dsh_C PF12316.8 KFQ93776.1 - 6e-72 242.4 26.2 6e-72 242.4 26.2 2.8 3 1 0 3 3 3 1 Segment polarity protein dishevelled (Dsh) C terminal Dishevelled PF02377.15 KFQ93776.1 - 1.2e-68 230.6 26.6 1.2e-68 230.6 26.6 2.8 3 0 0 3 3 3 1 Dishevelled specific domain PDZ PF00595.24 KFQ93776.1 - 1.1e-19 70.5 0.3 2e-19 69.7 0.3 1.4 1 0 0 1 1 1 1 PDZ domain DEP PF00610.21 KFQ93776.1 - 1.8e-16 59.9 0.1 3.4e-16 59.1 0.1 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ_6 PF17820.1 KFQ93776.1 - 4.8e-05 23.1 0.1 8.3e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFQ93776.1 - 0.0028 17.9 0.2 0.0058 16.9 0.2 1.5 1 0 0 1 1 1 1 PDZ domain Shufflon_N PF04917.12 KFQ93776.1 - 0.036 13.5 0.1 0.06 12.8 0.1 1.2 1 0 0 1 1 1 0 Bacterial shufflon protein, N-terminal constant region GLTP PF08718.11 KFQ93777.1 - 3.8e-39 134.4 0.0 4.8e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Beta-Casp PF10996.8 KFQ93778.1 - 9.7e-26 90.2 0.0 3.1e-25 88.6 0.0 1.9 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 KFQ93778.1 - 2.6e-23 82.5 0.0 5e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 KFQ93778.1 - 2.1e-20 72.4 0.1 4.3e-20 71.4 0.1 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 KFQ93778.1 - 4.4e-11 43.1 0.1 1.8e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFQ93778.1 - 1.2e-09 37.9 0.5 1.2e-08 34.7 0.1 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KFQ93778.1 - 0.00024 21.0 0.1 0.0018 18.2 0.0 2.5 3 1 0 3 3 3 1 Beta-lactamase superfamily domain PseudoU_synth_1 PF01416.20 KFQ93779.1 - 3.6e-35 120.7 0.0 2.7e-28 98.6 0.0 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase BAR_3 PF16746.5 KFQ93780.1 - 6.4e-75 251.9 10.8 1.1e-74 251.2 10.8 1.4 1 0 0 1 1 1 1 BAR domain of APPL family ArfGap PF01412.18 KFQ93780.1 - 1.8e-40 137.7 0.5 1.8e-40 137.7 0.5 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.29 KFQ93780.1 - 3.1e-14 53.3 0.2 3.1e-14 53.3 0.2 2.0 2 0 0 2 2 1 1 PH domain Ank_2 PF12796.7 KFQ93780.1 - 3.6e-13 49.9 0.5 1.9e-07 31.6 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFQ93780.1 - 2.8e-09 37.0 0.5 8.5e-06 26.0 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFQ93780.1 - 5.4e-09 36.4 0.5 0.0028 18.2 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ93780.1 - 1.3e-05 25.2 0.5 0.34 11.6 0.0 4.7 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 KFQ93780.1 - 3.2e-05 24.2 1.0 3.7 8.2 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat BAR PF03114.18 KFQ93780.1 - 0.0025 17.5 5.7 0.0047 16.6 5.7 1.4 1 0 0 1 1 1 1 BAR domain PH_11 PF15413.6 KFQ93780.1 - 0.012 16.0 5.0 0.096 13.1 2.5 2.8 2 1 0 2 2 1 0 Pleckstrin homology domain PH_8 PF15409.6 KFQ93780.1 - 0.1 12.9 0.1 0.39 11.0 0.1 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain Exonuc_VII_L PF02601.15 KFQ93780.1 - 0.11 12.1 2.2 0.21 11.1 2.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit ASC PF00858.24 KFQ93781.1 - 2.5e-98 329.9 10.9 3e-98 329.7 10.9 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DUF2632 PF10943.8 KFQ93781.1 - 0.11 12.1 1.4 0.2 11.2 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2632) UQ_con PF00179.26 KFQ93782.1 - 1.2e-18 67.1 0.0 1.8e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme C1q PF00386.21 KFQ93783.1 - 2.9e-06 27.5 0.0 8.2e-06 26.0 0.0 1.7 1 1 1 2 2 2 1 C1q domain Collagen PF01391.18 KFQ93783.1 - 0.0029 17.3 4.3 0.0045 16.7 4.3 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) TNF PF00229.18 KFQ93783.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 TNF(Tumour Necrosis Factor) family Galactosyl_T PF01762.21 KFQ93784.1 - 1.7e-28 99.8 0.0 2.2e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase EF-hand_1 PF00036.32 KFQ93785.1 - 1.4e-20 71.2 8.8 0.00045 19.6 0.0 6.3 6 0 0 6 6 6 5 EF hand EF-hand_7 PF13499.6 KFQ93785.1 - 6.8e-15 55.3 17.5 2.1e-07 31.3 0.3 4.8 2 2 4 6 6 6 5 EF-hand domain pair EF-hand_6 PF13405.6 KFQ93785.1 - 1.1e-12 46.8 3.2 0.27 11.3 0.0 5.5 6 0 0 6 6 6 4 EF-hand domain EF-hand_5 PF13202.6 KFQ93785.1 - 2e-12 46.0 2.6 0.0015 17.9 0.0 5.2 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 KFQ93785.1 - 1.7e-07 31.0 7.5 0.0094 15.8 0.0 5.2 4 2 1 5 5 5 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFQ93785.1 - 0.00063 20.0 16.0 0.18 12.1 1.7 3.5 2 1 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region Pex14_N PF04695.13 KFQ93785.1 - 0.0078 16.9 0.1 0.016 15.8 0.1 1.5 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region TNFR_c6 PF00020.18 KFQ93786.1 - 1.4e-15 57.4 29.7 9.3e-08 32.4 9.6 3.3 3 0 0 3 3 3 3 TNFR/NGFR cysteine-rich region RANK_CRD_2 PF18278.1 KFQ93786.1 - 0.0011 19.1 2.2 0.0011 19.1 2.2 2.0 1 1 0 1 1 1 1 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Ephrin_rec_like PF07699.13 KFQ93786.1 - 0.0046 16.7 15.9 0.071 12.9 1.3 2.5 2 0 0 2 2 2 2 Putative ephrin-receptor like Proteasome PF00227.26 KFQ93786.1 - 0.015 14.8 0.0 0.018 14.5 0.0 1.3 1 1 0 1 1 1 0 Proteasome subunit TNFR_c6 PF00020.18 KFQ93787.1 - 9.3e-05 22.7 0.3 9.3e-05 22.7 0.3 3.1 3 1 1 4 4 4 3 TNFR/NGFR cysteine-rich region PH PF00169.29 KFQ93788.1 - 0.0003 21.3 0.1 0.00041 20.8 0.1 1.2 1 0 0 1 1 1 1 PH domain DUF4501 PF14946.6 KFQ93789.1 - 7.2e-29 101.1 0.5 7.4e-29 101.1 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4501) EVC2_like PF12297.8 KFQ93789.1 - 0.21 10.2 0.1 0.21 10.2 0.1 1.0 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein zf-RING_5 PF14634.6 KFQ93790.1 - 3.3e-09 36.6 6.4 3.3e-09 36.6 6.4 2.0 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFQ93790.1 - 4.8e-09 36.4 6.8 4.8e-09 36.4 6.8 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KFQ93790.1 - 4.5e-08 33.0 7.7 4.5e-08 33.0 5.2 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFQ93790.1 - 1.4e-06 28.1 4.1 1.4e-06 28.1 4.1 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ93790.1 - 3.9e-06 26.6 7.0 3.9e-06 26.6 7.0 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFQ93790.1 - 3.5e-05 23.9 7.1 0.00019 21.5 7.1 2.4 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KFQ93790.1 - 0.00016 21.3 5.0 0.00036 20.2 5.0 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFQ93790.1 - 0.0031 17.3 10.6 0.0031 17.3 10.6 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) UBM PF14377.6 KFQ93790.1 - 0.012 15.1 0.4 0.022 14.2 0.4 1.5 1 0 0 1 1 1 0 Ubiquitin binding region zf-RING_4 PF14570.6 KFQ93790.1 - 0.027 14.3 5.7 0.027 14.3 5.7 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KFQ93790.1 - 0.2 12.0 6.4 1.3 9.3 6.4 2.4 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KFQ93790.1 - 0.6 10.3 7.5 5.5 7.2 4.9 2.7 2 1 0 2 2 2 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 KFQ93790.1 - 6.7 6.7 17.5 0.046 13.6 7.4 2.7 3 1 0 3 3 3 0 Prokaryotic RING finger family 4 Y_phosphatase PF00102.27 KFQ93791.1 - 5e-34 117.9 0.0 5.7e-34 117.7 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFQ93791.1 - 4.5e-06 26.5 0.1 9.5e-06 25.5 0.1 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFQ93791.1 - 0.00053 20.1 0.0 0.0011 19.1 0.0 1.6 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KFQ93791.1 - 0.00094 19.2 0.0 0.0012 18.9 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family UPF0254 PF06787.11 KFQ93791.1 - 0.013 15.2 0.1 0.016 15.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) SH2 PF00017.24 KFQ93792.1 - 5.9e-27 93.6 0.0 7e-27 93.4 0.0 1.1 1 0 0 1 1 1 1 SH2 domain Cbl_N3 PF02762.14 KFQ93792.1 - 0.025 14.4 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain SH2 PF00017.24 KFQ93793.1 - 5.5e-26 90.5 0.0 7.4e-26 90.1 0.0 1.2 1 0 0 1 1 1 1 SH2 domain SH2_2 PF14633.6 KFQ93793.1 - 0.048 13.1 0.0 0.17 11.2 0.0 1.5 1 1 0 1 1 1 0 SH2 domain Laminin_G_1 PF00054.23 KFQ93794.1 - 9e-111 365.6 0.0 2.4e-37 128.1 0.0 3.3 3 0 0 3 3 3 3 Laminin G domain Laminin_G_2 PF02210.24 KFQ93794.1 - 1e-73 245.9 0.0 5.7e-26 91.5 0.1 3.3 3 0 0 3 3 3 3 Laminin G domain Kazal_2 PF07648.15 KFQ93794.1 - 2.7e-72 238.7 121.7 4.3e-11 42.8 5.0 11.4 10 0 0 10 10 10 9 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFQ93794.1 - 1.1e-55 185.4 129.5 1.8e-10 40.7 0.1 10.8 10 0 0 10 10 10 9 Kazal-type serine protease inhibitor domain NtA PF03146.15 KFQ93794.1 - 2.9e-25 88.3 0.0 6.7e-25 87.1 0.0 1.7 1 0 0 1 1 1 1 Agrin NtA domain Laminin_EGF PF00053.24 KFQ93794.1 - 7.5e-19 67.6 31.9 6.1e-13 48.7 11.6 16.8 11 4 6 17 17 17 3 Laminin EGF domain SEA PF01390.20 KFQ93794.1 - 8.5e-16 58.0 0.0 2e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 SEA domain EGF PF00008.27 KFQ93794.1 - 1.4e-12 47.6 50.8 4e-06 27.0 8.4 13.9 12 0 0 12 12 12 4 EGF-like domain Laminin_G_3 PF13385.6 KFQ93794.1 - 2.6e-11 43.9 0.0 0.00022 21.4 0.0 3.3 3 0 0 3 3 3 3 Concanavalin A-like lectin/glucanases superfamily hEGF PF12661.7 KFQ93794.1 - 0.0024 18.4 16.4 0.0046 17.5 3.7 16.0 16 0 0 16 16 16 4 Human growth factor-like EGF Hairy_orange PF07527.13 KFQ93795.1 - 6.9e-20 71.0 0.4 1.2e-19 70.2 0.4 1.4 1 0 0 1 1 1 1 Hairy Orange HLH PF00010.26 KFQ93795.1 - 4.5e-05 23.3 0.2 0.00014 21.8 0.2 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Nup35_RRM_2 PF14605.6 KFQ93795.1 - 0.19 11.7 0.0 0.41 10.7 0.0 1.5 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Cytadhesin_P30 PF07271.11 KFQ93795.1 - 1.5 8.3 10.8 2.1 7.9 10.8 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 Kelch_1 PF01344.25 KFQ93796.1 - 3.7e-79 260.1 15.3 3.8e-16 58.4 0.3 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFQ93796.1 - 1.7e-44 148.7 3.7 2.3e-09 37.2 0.0 6.5 1 1 5 6 6 6 6 Kelch motif BACK PF07707.15 KFQ93796.1 - 1.8e-38 130.8 0.2 4.1e-38 129.6 0.2 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 KFQ93796.1 - 7e-33 113.2 0.8 1.2e-32 112.4 0.2 1.7 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.6 KFQ93796.1 - 1.6e-27 95.2 1.2 2.7e-06 27.3 0.0 6.3 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 KFQ93796.1 - 3.6e-27 94.1 15.7 7.8e-07 29.2 0.1 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KFQ93796.1 - 5.1e-26 89.6 2.0 0.00014 21.7 0.1 6.0 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 KFQ93796.1 - 5.3e-09 35.9 5.5 0.1 12.6 0.0 5.5 5 0 0 5 5 5 3 Kelch motif BA14K PF07886.11 KFQ93796.1 - 0.036 14.0 2.0 0.77 9.7 0.0 3.7 4 0 0 4 4 4 0 BA14K-like protein XPA_C PF05181.12 KFQ93796.1 - 0.12 12.3 0.2 27 4.8 0.0 2.7 2 0 0 2 2 2 0 XPA protein C-terminus PQQ_3 PF13570.6 KFQ93796.1 - 3.3 8.3 13.0 23 5.7 0.1 5.7 6 0 0 6 6 6 0 PQQ-like domain Noc2 PF03715.13 KFQ93797.1 - 1.3e-125 418.6 9.5 1.3e-125 418.6 9.5 2.1 2 0 0 2 2 2 1 Noc2p family SAM_1 PF00536.30 KFQ93798.1 - 2.5e-05 24.6 0.0 5.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFQ93798.1 - 0.0057 16.7 1.0 0.0095 16.0 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Enolase_C PF00113.22 KFQ93799.1 - 3.6e-159 528.7 0.0 4.6e-159 528.4 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KFQ93799.1 - 1.8e-60 202.8 0.1 3.2e-60 202.0 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KFQ93799.1 - 4.7e-08 32.9 0.0 6.8e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KFQ93799.1 - 0.0019 17.4 0.9 0.0029 16.8 0.3 1.6 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Carb_anhydrase PF00194.21 KFQ93800.1 - 5.7e-87 291.5 0.0 7.4e-87 291.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Pentaxin PF00354.17 KFQ93800.1 - 2.7e-36 125.1 0.0 4.4e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.6 KFQ93800.1 - 2e-09 37.7 1.0 4.6e-09 36.6 1.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Sugar_tr PF00083.24 KFQ93801.1 - 7.4e-131 437.1 24.0 8.5e-131 436.9 24.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFQ93801.1 - 1.2e-19 70.5 30.5 2.1e-18 66.4 24.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 KFQ93801.1 - 1.9 8.8 9.9 8.2 6.7 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) Glucosamine_iso PF01182.20 KFQ93802.1 - 3.6e-60 203.6 0.0 5.9e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase G6PD_C PF02781.16 KFQ93802.1 - 4.8e-54 183.5 0.0 7.6e-54 182.9 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KFQ93802.1 - 6.2e-36 124.7 0.0 1.8e-35 123.2 0.0 1.8 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF5617 PF18493.1 KFQ93802.1 - 0.082 13.0 0.8 0.2 11.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5617) SPRY PF00622.28 KFQ93803.1 - 2.6e-19 69.5 0.0 3.7e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.16 KFQ93803.1 - 4.1e-11 43.0 2.9 7.4e-11 42.2 2.9 1.4 1 0 0 1 1 1 1 SOCS box Mito_carr PF00153.27 KFQ93804.1 - 6.4e-61 202.3 1.6 3.4e-20 71.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2448 PF10476.9 KFQ93805.1 - 1.5e-95 318.9 1.6 2.3e-95 318.3 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2448) Ima1_N PF09779.9 KFQ93805.1 - 7.4e-34 117.5 12.2 2e-33 116.1 12.2 1.7 1 0 0 1 1 1 1 Ima1 N-terminal domain zf-RRPl_C4 PF17026.5 KFQ93805.1 - 0.12 12.5 12.2 0.061 13.4 9.3 2.2 2 1 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Cadherin PF00028.17 KFQ93808.1 - 5.3e-15 55.6 0.0 6.9e-07 29.6 0.0 2.8 2 0 0 2 2 2 2 Cadherin domain Laminin_G_3 PF13385.6 KFQ93808.1 - 3.7e-05 23.9 0.0 8.1e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily CDC45 PF02724.14 KFQ93808.1 - 9.8e-05 20.8 2.5 0.00013 20.4 2.5 1.1 1 0 0 1 1 1 1 CDC45-like protein Laminin_G_2 PF02210.24 KFQ93808.1 - 0.0015 19.1 0.2 0.012 16.2 0.0 2.6 3 0 0 3 3 3 1 Laminin G domain V_ATPase_I PF01496.19 KFQ93808.1 - 0.026 12.5 1.6 0.039 11.9 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 KFQ93808.1 - 0.078 12.7 0.3 0.16 11.7 0.3 1.4 1 0 0 1 1 1 0 Connexin SID-1_RNA_chan PF13965.6 KFQ93808.1 - 0.1 11.0 0.5 0.15 10.4 0.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Zip PF02535.22 KFQ93808.1 - 0.15 11.3 2.6 0.24 10.6 2.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RasGAP PF00616.19 KFQ93808.1 - 1.6 8.4 3.7 2.9 7.5 3.7 1.4 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase TRAP_alpha PF03896.16 KFQ93808.1 - 2.4 7.3 6.9 5.4 6.1 6.9 1.6 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit ICAT PF06384.11 KFQ93809.1 - 2.5e-19 69.3 0.0 2.6e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 Beta-catenin-interacting protein ICAT DUF3140 PF11338.8 KFQ93809.1 - 0.14 12.6 0.0 0.17 12.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) ICAT PF06384.11 KFQ93810.1 - 9.1e-27 93.1 2.3 1.9e-26 92.1 0.0 2.4 2 1 1 3 3 3 1 Beta-catenin-interacting protein ICAT CAMP_factor PF07373.11 KFQ93810.1 - 0.00029 20.5 1.1 0.00041 20.0 1.1 1.2 1 0 0 1 1 1 1 CAMP factor (Cfa) GvpG PF05120.12 KFQ93810.1 - 0.0028 17.6 10.5 0.015 15.3 0.2 2.4 2 0 0 2 2 2 1 Gas vesicle protein G Serine_rich PF08824.10 KFQ93810.1 - 0.0034 17.4 1.7 0.0048 16.9 1.7 1.3 1 0 0 1 1 1 1 Serine rich protein interaction domain DUF892 PF05974.12 KFQ93810.1 - 0.0099 15.9 2.0 0.019 15.0 2.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF892) Spc7 PF08317.11 KFQ93810.1 - 0.021 13.7 6.7 0.029 13.3 6.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Importin_rep_6 PF18829.1 KFQ93810.1 - 0.04 14.1 0.5 0.067 13.3 0.5 1.4 1 0 0 1 1 1 0 Importin repeat 6 CK2S PF15011.6 KFQ93810.1 - 0.043 13.7 8.6 0.53 10.2 0.1 2.8 1 1 1 3 3 3 0 Casein Kinase 2 substrate FlxA PF14282.6 KFQ93810.1 - 0.051 13.6 11.1 0.11 12.4 9.0 2.2 1 1 1 2 2 2 0 FlxA-like protein DUF3313 PF11769.8 KFQ93810.1 - 0.062 13.1 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) TetR_C_7 PF14246.6 KFQ93810.1 - 0.069 13.2 0.3 0.17 11.9 0.1 1.8 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain Laminin_II PF06009.12 KFQ93810.1 - 0.2 11.7 5.4 2 8.4 1.3 2.5 1 1 1 2 2 2 0 Laminin Domain II DMAP_binding PF06464.11 KFQ93810.1 - 0.23 12.3 0.4 0.23 12.3 0.4 2.3 2 0 0 2 2 2 0 DMAP1-binding Domain DUF4254 PF14063.6 KFQ93810.1 - 0.29 11.0 5.8 0.4 10.5 1.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4254) Cauli_AT PF03233.13 KFQ93810.1 - 0.3 11.0 3.1 0.58 10.1 3.1 1.4 1 0 0 1 1 1 0 Aphid transmission protein DUF2408 PF10303.9 KFQ93810.1 - 0.47 11.0 7.1 0.73 10.4 6.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Allexi_40kDa PF05549.11 KFQ93810.1 - 0.61 9.6 3.4 0.75 9.3 3.0 1.3 1 1 0 1 1 1 0 Allexivirus 40kDa protein WXG100 PF06013.12 KFQ93810.1 - 0.68 10.2 5.0 0.47 10.7 1.1 2.6 3 1 0 3 3 2 0 Proteins of 100 residues with WXG DUF1216 PF06746.11 KFQ93810.1 - 0.73 9.8 4.7 0.83 9.7 3.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1216) NPV_P10 PF05531.12 KFQ93810.1 - 0.9 10.0 5.2 1.3 9.5 3.7 2.2 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein Baculo_p24 PF05073.12 KFQ93810.1 - 1.1 9.0 4.5 9.8 5.9 2.5 2.0 1 1 1 2 2 2 0 Baculovirus P24 capsid protein DASH_Dam1 PF08653.10 KFQ93810.1 - 2.5 8.0 3.9 18 5.2 0.8 2.6 1 1 2 3 3 3 0 DASH complex subunit Dam1 XhlA PF10779.9 KFQ93810.1 - 2.5 8.3 7.2 18 5.6 7.2 2.3 1 1 0 1 1 1 0 Haemolysin XhlA DUF1664 PF07889.12 KFQ93810.1 - 3.2 7.8 7.0 5 7.2 4.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) YojJ PF10372.9 KFQ93810.1 - 7.6 6.7 9.8 4.8 7.3 1.3 3.0 3 1 1 4 4 3 0 Bacterial membrane-spanning protein N-terminus FapA PF03961.13 KFQ93810.1 - 8.6 4.8 8.0 10 4.6 7.5 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A CorA PF01544.18 KFQ93810.1 - 9.1 5.5 8.7 30 3.8 7.2 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein PSK_trans_fac PF07704.11 KFQ93810.1 - 9.8 7.0 8.4 3 8.7 2.6 2.5 1 1 1 2 2 2 0 Rv0623-like transcription factor CTP_transf_like PF01467.26 KFQ93811.1 - 1.1e-32 113.2 0.0 3.3e-32 111.6 0.0 1.7 1 1 0 1 1 1 1 Cytidylyltransferase-like Lipocalin PF00061.23 KFQ93812.1 - 1.3e-18 67.6 0.6 1.4e-18 67.4 0.6 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 KFQ93812.1 - 4.8e-05 23.3 0.4 5.9e-05 23.0 0.4 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Ufd2P_core PF10408.9 KFQ93813.1 - 3.5e-202 673.4 14.9 4.6e-202 673.0 14.9 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KFQ93813.1 - 3.7e-26 91.1 1.1 9.1e-26 89.8 0.4 2.2 2 0 0 2 2 2 1 U-box domain Kinesin PF00225.23 KFQ93814.1 - 1.2e-116 389.3 0.6 2e-116 388.6 0.6 1.3 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 KFQ93814.1 - 9e-87 289.9 0.4 9e-87 289.9 0.4 2.7 4 0 0 4 4 4 1 Kinesin-associated DUF3694 PF12473.8 KFQ93814.1 - 4.4e-39 134.6 0.0 1.4e-38 133.0 0.0 2.0 1 0 0 1 1 1 1 Kinesin protein Microtub_bd PF16796.5 KFQ93814.1 - 2.1e-25 89.4 0.2 6.5e-24 84.6 0.1 2.9 2 0 0 2 2 2 1 Microtubule binding PH PF00169.29 KFQ93814.1 - 5.3e-13 49.4 0.1 2.4e-11 44.1 0.0 3.7 4 0 0 4 4 4 1 PH domain FHA PF00498.26 KFQ93814.1 - 5.9e-08 32.9 0.3 2.6e-07 30.9 0.1 2.3 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KFQ93814.1 - 0.0019 18.5 0.0 0.0053 17.0 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain KIF1B PF12423.8 KFQ93814.1 - 0.023 15.1 0.7 0.023 15.1 0.7 2.7 2 0 0 2 2 2 0 Kinesin protein 1B 6PGD PF00393.19 KFQ93815.1 - 3.1e-132 440.3 0.0 3.8e-132 440.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KFQ93815.1 - 1.2e-49 168.5 0.0 1.7e-49 168.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFQ93815.1 - 0.013 15.7 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KFQ93815.1 - 0.083 13.5 0.2 0.25 11.9 0.1 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent CENP-S PF15630.6 KFQ93816.1 - 2.9e-32 110.8 0.8 2.9e-32 110.8 0.8 1.6 2 0 0 2 2 2 1 CENP-S protein CENP-T_C PF15511.6 KFQ93816.1 - 1.7e-09 37.8 0.9 2.1e-09 37.4 0.9 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KFQ93816.1 - 0.0002 21.7 1.0 0.0002 21.7 1.0 2.1 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KFQ93816.1 - 0.01 15.8 0.3 0.022 14.8 0.1 1.6 1 1 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 KFQ93816.1 - 0.014 15.5 0.1 0.016 15.3 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIID-18kDa PF02269.16 KFQ93816.1 - 0.13 12.3 1.4 0.19 11.8 1.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit TAF PF02969.17 KFQ93816.1 - 0.22 11.7 2.9 0.41 10.8 0.5 2.7 1 1 2 3 3 3 0 TATA box binding protein associated factor (TAF) DFF-C PF09033.10 KFQ93817.1 - 5.1e-64 215.1 9.4 5.1e-64 215.1 9.4 2.1 2 0 0 2 2 2 1 DNA Fragmentation factor 45kDa, C terminal domain CIDE-N PF02017.15 KFQ93817.1 - 1e-17 63.9 0.6 7.9e-16 57.9 0.0 2.9 3 0 0 3 3 3 1 CIDE-N domain SesA PF17107.5 KFQ93817.1 - 0.14 12.3 3.6 0.18 12.0 0.3 2.6 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases HR1 PF02185.16 KFQ93817.1 - 0.84 9.8 16.0 0.86 9.8 2.9 2.8 3 1 0 3 3 3 0 Hr1 repeat HTH_57 PF18679.1 KFQ93817.1 - 1.5 9.2 5.5 0.6 10.5 1.8 2.2 2 1 0 2 2 2 0 ThcOx helix turn helix domain Yuri_gagarin PF15934.5 KFQ93817.1 - 1.6 8.5 10.1 0.16 11.8 4.0 2.0 2 0 0 2 2 2 0 Yuri gagarin PCRF PF03462.18 KFQ93817.1 - 2.8 7.8 7.8 0.61 9.9 2.1 2.0 2 0 0 2 2 2 0 PCRF domain AAA_23 PF13476.6 KFQ93817.1 - 3.5 8.1 8.8 0.79 10.2 2.7 2.0 2 0 0 2 2 2 0 AAA domain Muted PF14942.6 KFQ93817.1 - 5.5 7.3 9.6 3.6 7.9 4.3 2.4 2 1 1 3 3 3 0 Organelle biogenesis, Muted-like protein DUF4164 PF13747.6 KFQ93817.1 - 7.6 6.9 16.2 4.6 7.6 1.1 3.4 2 1 2 4 4 4 0 Domain of unknown function (DUF4164) Pex14_N PF04695.13 KFQ93818.1 - 5.4e-22 79.1 2.0 5.4e-22 79.1 2.0 3.9 2 2 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region HemX PF04375.14 KFQ93818.1 - 0.00014 21.2 4.6 0.00014 21.2 4.6 1.5 2 0 0 2 2 2 1 HemX, putative uroporphyrinogen-III C-methyltransferase DUF948 PF06103.11 KFQ93818.1 - 0.0028 17.9 0.4 0.0064 16.7 0.4 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) CC2-LZ PF16516.5 KFQ93818.1 - 0.018 15.4 2.0 0.018 15.4 2.0 2.3 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Calici_PP_N PF08405.11 KFQ93818.1 - 0.044 12.6 0.1 0.062 12.1 0.1 1.1 1 0 0 1 1 1 0 Viral polyprotein N-terminal Fib_alpha PF08702.10 KFQ93818.1 - 0.088 13.0 4.6 0.21 11.8 4.6 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family GLE1 PF07817.13 KFQ93818.1 - 0.16 11.2 3.2 0.24 10.6 3.2 1.2 1 0 0 1 1 1 0 GLE1-like protein Phage_Gp23 PF10669.9 KFQ93818.1 - 0.43 10.9 13.6 1.1 9.6 4.7 2.3 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) SPG4 PF17325.2 KFQ93818.1 - 6.5 7.9 8.5 21 6.3 3.3 2.3 2 0 0 2 2 2 0 Stationary phase protein 4 Cwf_Cwc_15 PF04889.12 KFQ93819.1 - 0.04 13.7 18.1 0.068 12.9 18.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 KFQ93819.1 - 0.09 12.4 19.1 0.16 11.5 19.1 1.4 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 KFQ93819.1 - 0.29 9.3 23.8 0.42 8.8 23.8 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 KFQ93819.1 - 9 6.1 20.4 15 5.4 20.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region zf-C2H2 PF00096.26 KFQ93820.1 - 0.037 14.5 26.6 0.11 13.0 2.8 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 KFQ93820.1 - 0.038 14.3 13.2 3.1 8.2 2.1 3.5 1 1 2 3 3 3 0 C2H2-type zinc ribbon Fumble PF03630.14 KFQ93822.1 - 0.032 13.4 0.1 0.046 12.9 0.1 1.1 1 0 0 1 1 1 0 Fumble TAF6_C PF07571.13 KFQ93822.1 - 0.14 12.5 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain TDP43_N PF18694.1 KFQ93823.1 - 2.4e-33 113.8 0.0 4.1e-33 113.0 0.0 1.4 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain RRM_1 PF00076.22 KFQ93823.1 - 8e-28 96.1 0.2 2.4e-15 56.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFQ93823.1 - 1.8e-07 31.2 0.7 0.016 15.3 0.0 3.1 3 1 0 3 3 3 2 RNA recognition motif RL PF17797.1 KFQ93823.1 - 0.00056 19.8 0.0 0.24 11.4 0.0 2.3 2 0 0 2 2 2 2 RL domain RRM_3 PF08777.11 KFQ93823.1 - 0.00087 19.3 0.0 0.14 12.2 0.0 2.4 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 KFQ93823.1 - 0.0053 16.7 0.1 0.14 12.2 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DUF4651 PF15513.6 KFQ93823.1 - 0.068 13.0 0.0 7.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) CUB PF00431.20 KFQ93824.1 - 3.8e-18 65.8 0.1 5.8e-18 65.2 0.1 1.3 1 0 0 1 1 1 1 CUB domain FXa_inhibition PF14670.6 KFQ93824.1 - 8.4e-08 32.4 9.1 8.4e-08 32.4 9.1 1.7 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 KFQ93824.1 - 2.6e-07 30.7 7.6 5.1e-07 29.8 7.6 1.5 1 0 0 1 1 1 1 Calcium-binding EGF domain cEGF PF12662.7 KFQ93824.1 - 0.00014 21.7 1.5 0.00014 21.7 1.5 2.5 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF PF00008.27 KFQ93824.1 - 0.001 19.3 9.8 0.0029 17.9 9.8 1.8 1 1 0 1 1 1 1 EGF-like domain CUB_2 PF02408.20 KFQ93824.1 - 0.033 13.9 0.3 0.051 13.3 0.3 1.5 1 1 0 1 1 1 0 CUB-like domain DUF3440 PF11922.8 KFQ93824.1 - 0.096 12.4 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) Somatostatin PF03002.15 KFQ93825.1 - 8.3e-06 25.6 2.8 1.3e-05 25.0 2.8 1.3 1 0 0 1 1 1 1 Somatostatin/Cortistatin family Spermine_synth PF01564.17 KFQ93827.1 - 1.2e-64 217.2 0.0 1.9e-64 216.6 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_31 PF13847.6 KFQ93827.1 - 1.2e-05 25.1 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFQ93827.1 - 0.00018 22.2 0.0 0.00073 20.2 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 KFQ93827.1 - 0.058 13.3 0.1 0.12 12.3 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_30 PF05430.11 KFQ93827.1 - 0.084 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 KFQ93827.1 - 0.089 13.5 0.0 0.34 11.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain DNA_pol_A_exo1 PF01612.20 KFQ93828.1 - 3.9e-49 166.7 2.1 7.8e-49 165.8 2.1 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 KFQ93828.1 - 8.2e-24 84.1 0.1 5.9e-23 81.4 0.0 2.5 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 KFQ93828.1 - 9e-14 51.2 0.4 1.9e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 HRDC domain DUF5072 PF16807.5 KFQ93828.1 - 0.087 12.9 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5072) ATC_hydrolase PF14196.6 KFQ93828.1 - 3.4 8.4 7.1 68 4.2 1.9 3.8 3 1 1 4 4 4 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase FAT PF02259.23 KFQ93829.1 - 1.3e-130 435.6 12.8 1.3e-130 435.6 12.8 2.4 3 0 0 3 3 3 1 FAT domain PI3_PI4_kinase PF00454.27 KFQ93829.1 - 1.9e-76 257.2 0.1 3.9e-76 256.2 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KFQ93829.1 - 2.5e-60 203.0 6.8 1.7e-58 197.0 0.1 4.8 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KFQ93829.1 - 5.2e-46 155.1 0.4 5.2e-46 155.1 0.4 3.9 5 0 0 5 5 3 1 FKBP12-rapamycin binding domain FATC PF02260.20 KFQ93829.1 - 1.8e-12 46.8 0.1 4.8e-12 45.5 0.1 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 KFQ93829.1 - 2.3e-09 37.5 9.4 0.2 12.1 0.0 8.7 11 1 1 12 12 11 3 HEAT repeats IFRD PF05004.13 KFQ93829.1 - 1.2e-06 27.9 2.4 0.18 10.9 0.0 4.8 4 1 1 5 5 5 2 Interferon-related developmental regulator (IFRD) HEAT PF02985.22 KFQ93829.1 - 5.5e-06 26.2 20.1 10 6.7 0.1 13.3 15 0 0 15 15 14 1 HEAT repeat Vac14_Fab1_bd PF12755.7 KFQ93829.1 - 0.0021 18.6 3.0 11 6.7 0.0 6.6 5 1 2 7 7 7 1 Vacuolar 14 Fab1-binding region UME PF08064.13 KFQ93829.1 - 0.0024 17.8 7.9 0.39 10.6 0.3 5.4 5 0 0 5 5 5 2 UME (NUC010) domain EPSP_synthase PF00275.20 KFQ93829.1 - 0.0073 15.0 0.0 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) HEAT_EZ PF13513.6 KFQ93829.1 - 0.01 16.3 35.3 0.038 14.5 0.0 12.9 15 1 1 16 16 13 0 HEAT-like repeat TPR_19 PF14559.6 KFQ93829.1 - 0.058 13.9 4.0 2.5 8.7 0.0 4.0 5 0 0 5 5 3 0 Tetratricopeptide repeat CFIA_Pcf11 PF11526.8 KFQ93829.1 - 0.12 12.9 3.1 0.66 10.5 3.1 2.3 1 0 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 DUF1104 PF06518.11 KFQ93829.1 - 4.8 7.6 6.2 32 5.0 0.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) UbiA PF01040.18 KFQ93830.1 - 7e-41 140.2 11.5 8.8e-41 139.9 11.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Patched PF02460.18 KFQ93831.1 - 7.7e-20 70.6 29.0 1.5e-16 59.8 3.8 2.5 3 0 0 3 3 3 2 Patched family MMPL PF03176.15 KFQ93831.1 - 4e-14 52.3 30.7 2.1e-09 36.8 6.2 2.3 2 0 0 2 2 2 2 MMPL family Sterol-sensing PF12349.8 KFQ93831.1 - 1.6e-12 47.6 11.5 1.6e-12 47.6 11.5 2.8 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 KFQ93831.1 - 0.012 13.3 7.6 0.026 12.2 7.6 1.4 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family FBA PF04300.13 KFQ93832.1 - 3e-80 268.1 0.2 3.8e-80 267.8 0.2 1.1 1 0 0 1 1 1 1 F-box associated region F-box PF00646.33 KFQ93832.1 - 1.3e-07 31.3 2.7 2.2e-07 30.6 2.7 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFQ93832.1 - 2.2e-07 30.6 2.1 5.6e-07 29.4 2.1 1.7 1 0 0 1 1 1 1 F-box-like FBA PF04300.13 KFQ93833.1 - 8.3e-77 256.9 0.5 1e-76 256.6 0.5 1.1 1 0 0 1 1 1 1 F-box associated region F-box-like PF12937.7 KFQ93833.1 - 1.2e-10 41.1 5.4 3.5e-10 39.6 5.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFQ93833.1 - 4.4e-09 36.0 2.4 1.1e-08 34.7 2.4 1.8 1 0 0 1 1 1 1 F-box domain HORMA PF02301.18 KFQ93834.1 - 1.5e-09 37.8 0.1 2.7e-09 36.9 0.1 1.3 1 1 0 1 1 1 1 HORMA domain Draxin PF15550.6 KFQ93835.1 - 2.7e-144 480.9 10.7 3.1e-144 480.8 10.7 1.0 1 0 0 1 1 1 1 Draxin Dickkopf_N PF04706.12 KFQ93835.1 - 5.1 7.7 14.3 11 6.6 14.3 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region AGTRAP PF06396.11 KFQ93836.1 - 3.2e-56 189.2 3.6 3.5e-56 189.1 3.6 1.0 1 0 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) Smim3 PF17307.2 KFQ93836.1 - 0.5 9.9 3.7 2.2 7.8 0.1 2.3 2 0 0 2 2 2 0 Small integral membrane protein 3 Voltage_CLC PF00654.20 KFQ93837.1 - 4.2e-98 328.9 22.3 1.2e-96 324.1 18.4 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 KFQ93837.1 - 8e-15 55.0 0.4 2.1e-08 34.5 0.0 3.0 3 0 0 3 3 3 2 CBS domain ANP PF00212.18 KFQ93838.1 - 2.2e-14 53.3 9.8 3e-14 52.9 9.8 1.2 1 0 0 1 1 1 1 Atrial natriuretic peptide ANP PF00212.18 KFQ93839.1 - 5.4e-15 55.3 9.4 9.7e-15 54.4 9.4 1.5 1 0 0 1 1 1 1 Atrial natriuretic peptide NFRKB_winged PF14465.6 KFQ93839.1 - 0.12 12.5 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 NFRKB Winged Helix-like Guanylate_cyc PF00211.20 KFQ93840.1 - 3.9e-69 232.0 0.0 4.6e-69 231.7 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KFQ93840.1 - 6.2e-05 22.5 1.5 8.5e-05 22.1 1.0 1.5 2 0 0 2 2 2 1 Heme NO binding associated Trypsin PF00089.26 KFQ93841.1 - 3.8e-67 226.3 1.6 4.3e-67 226.2 1.6 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFQ93841.1 - 7.1e-07 30.2 0.0 1e-06 29.7 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFQ93841.1 - 6.8e-05 23.2 0.2 0.00011 22.6 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF2152 PF10222.9 KFQ93842.1 - 1.2e-191 638.2 0.0 1.3e-191 638.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2152) 2OG-FeII_Oxy PF03171.20 KFQ93843.1 - 2.3e-06 28.0 0.0 5.2e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Anp1 PF03452.14 KFQ93843.1 - 1e-05 25.1 0.7 0.16 11.3 0.1 3.0 2 1 0 3 3 3 2 Anp1 2OG-FeII_Oxy_3 PF13640.6 KFQ93843.1 - 4.1e-05 24.4 0.1 0.00013 22.8 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Fzo_mitofusin PF04799.13 KFQ93844.1 - 3e-75 251.2 14.8 8.6e-75 249.7 4.1 2.9 3 0 0 3 3 3 2 fzo-like conserved region Dynamin_N PF00350.23 KFQ93844.1 - 3.5e-23 82.5 1.6 1.3e-22 80.7 0.0 2.7 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 KFQ93844.1 - 6e-08 32.8 0.0 3.9e-07 30.1 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Synaptobrevin PF00957.21 KFQ93844.1 - 0.21 11.4 3.2 0.41 10.5 0.1 2.6 2 0 0 2 2 2 0 Synaptobrevin GTP_EFTU PF00009.27 KFQ93844.1 - 0.55 9.8 2.9 11 5.5 2.9 2.8 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Apolipoprotein PF01442.18 KFQ93844.1 - 0.9 9.4 11.4 1.5 8.7 4.5 2.8 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Streptin-Immun PF11083.8 KFQ93844.1 - 1.9 8.9 5.6 0.4 11.1 0.4 2.4 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein MIIP PF15734.5 KFQ93845.1 - 8.6e-49 166.9 0.2 9.2e-49 166.8 0.2 1.0 1 0 0 1 1 1 1 Migration and invasion-inhibitory TNFR_c6 PF00020.18 KFQ93846.1 - 2.9e-13 50.0 45.1 3e-05 24.3 2.1 4.8 3 1 0 4 4 4 4 TNFR/NGFR cysteine-rich region TNFR_c6 PF00020.18 KFQ93847.1 - 7.2e-21 74.3 59.9 3.1e-08 33.9 9.8 4.7 5 0 0 5 5 5 4 TNFR/NGFR cysteine-rich region DUF1180 PF06679.12 KFQ93847.1 - 2 8.8 8.6 1.4 9.3 4.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) Presenilin PF01080.17 KFQ93847.1 - 3.3 6.4 4.8 4.2 6.0 4.8 1.2 1 0 0 1 1 1 0 Presenilin Glycophorin_A PF01102.18 KFQ93847.1 - 5.7 7.2 6.3 2.5 8.4 0.2 2.5 2 0 0 2 2 2 0 Glycophorin A Macoilin PF09726.9 KFQ93847.1 - 7.2 5.0 9.3 9.9 4.6 9.3 1.3 1 0 0 1 1 1 0 Macoilin family Hus1 PF04005.12 KFQ93849.1 - 0.014 14.5 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 Hus1-like protein adh_short PF00106.25 KFQ93850.1 - 5.3e-33 114.1 0.0 7.9e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFQ93850.1 - 1.7e-21 76.9 0.0 5.5e-21 75.2 0.0 1.8 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFQ93850.1 - 5.2e-13 49.3 0.2 1.7e-12 47.6 0.2 1.8 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFQ93850.1 - 2.2e-07 30.3 0.0 3e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KFQ93850.1 - 0.007 15.9 0.1 0.01 15.3 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KFQ93850.1 - 0.023 14.7 0.1 0.053 13.6 0.1 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase zf-RING_5 PF14634.6 KFQ93850.1 - 0.16 11.9 0.9 0.65 10.0 0.2 2.1 2 0 0 2 2 2 0 zinc-RING finger domain Abhydrolase_3 PF07859.13 KFQ93852.1 - 2.4e-47 161.5 0.0 2.3e-35 122.4 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 KFQ93852.1 - 2.2e-05 23.5 0.0 0.033 13.1 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Say1_Mug180 PF10340.9 KFQ93852.1 - 0.0057 15.6 0.0 0.0078 15.1 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase AXE1 PF05448.12 KFQ93852.1 - 0.037 12.7 0.0 0.049 12.3 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 KFQ93852.1 - 0.086 12.1 0.0 0.15 11.3 0.0 1.4 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFQ93852.1 - 0.093 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.20 KFQ93852.1 - 0.18 11.5 0.0 0.42 10.2 0.0 1.5 1 1 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 KFQ93853.1 - 2.5e-43 148.4 0.0 6e-30 104.7 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 KFQ93853.1 - 0.018 13.9 0.1 0.16 10.8 0.1 1.9 1 1 0 1 1 1 0 Carboxylesterase family AXE1 PF05448.12 KFQ93853.1 - 0.035 12.8 0.0 0.05 12.3 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KFQ93853.1 - 0.061 12.8 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KFQ93853.1 - 0.084 12.7 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KFQ93854.1 - 1e-50 172.5 0.0 3.3e-37 128.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 KFQ93854.1 - 0.00013 21.0 0.0 0.00044 19.3 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFQ93855.1 - 9e-59 198.9 0.0 1.5e-45 155.6 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 KFQ93855.1 - 3.6e-07 29.4 0.3 3.8e-06 26.0 0.3 2.0 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KFQ93855.1 - 9.9e-05 21.4 0.0 0.00014 20.9 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KFQ93855.1 - 0.065 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase_phd PF10503.9 KFQ93855.1 - 0.11 12.0 0.2 0.21 11.1 0.1 1.4 1 1 0 1 1 1 0 Esterase PHB depolymerase LRR_8 PF13855.6 KFQ93857.1 - 3.8e-34 116.2 21.5 7.6e-14 51.2 4.9 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFQ93857.1 - 4.8e-15 55.4 16.6 3.6e-05 24.1 0.8 4.7 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFQ93857.1 - 1.6e-10 41.0 1.6 3.6e-10 39.9 0.1 2.0 1 1 1 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFQ93857.1 - 2.5e-07 30.3 9.8 0.71 10.7 0.0 6.6 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_9 PF14580.6 KFQ93857.1 - 3.6e-06 26.6 3.7 8.9e-05 22.1 1.5 2.1 1 1 1 2 2 2 2 Leucine-rich repeat DUF3557 PF12078.8 KFQ93857.1 - 0.0029 17.6 0.1 0.0077 16.2 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3557) LRR_3 PF07725.12 KFQ93857.1 - 0.17 11.8 5.4 4.2 7.4 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich Repeat LRRNT PF01462.18 KFQ93857.1 - 0.23 11.1 3.8 0.91 9.2 3.8 2.1 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 KFQ93857.1 - 0.29 11.3 0.2 0.29 11.3 0.2 5.4 6 0 0 6 6 6 0 Leucine Rich repeat zf-C2H2 PF00096.26 KFQ93858.1 - 1.8e-18 65.9 61.4 0.0026 18.1 2.0 8.9 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ93858.1 - 8.5e-17 60.4 59.6 0.0053 17.5 2.4 9.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFQ93858.1 - 2e-10 40.4 44.3 0.0037 17.2 3.1 7.3 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ93858.1 - 0.00089 19.5 27.1 0.24 11.7 0.7 6.9 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KFQ93858.1 - 0.014 15.8 0.2 0.014 15.8 0.2 7.0 6 1 0 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger zf-CHCC PF10276.9 KFQ93858.1 - 0.17 12.0 8.5 1.9 8.6 0.0 4.0 4 0 0 4 4 4 0 Zinc-finger domain PyrI_C PF02748.15 KFQ93858.1 - 0.64 10.0 21.0 0.49 10.3 0.2 6.4 6 1 1 7 7 7 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-MYST PF17772.1 KFQ93858.1 - 0.93 9.2 15.7 2.3 7.9 0.2 5.4 5 0 0 5 5 5 0 MYST family zinc finger domain HypA PF01155.19 KFQ93858.1 - 1.9 8.5 15.8 6.3 6.8 0.2 5.2 4 1 0 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PhnA_Zn_Ribbon PF08274.12 KFQ93858.1 - 6.3 6.9 6.3 40 4.3 0.0 3.3 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-C2H2_3rep PF18868.1 KFQ93858.1 - 7.2 7.3 32.0 30 5.3 0.1 8.4 5 3 2 7 7 7 0 Zinc finger C2H2-type, 3 repeats DUF148 PF02520.17 KFQ93860.1 - 0.0066 16.5 7.5 0.022 14.9 7.5 1.9 1 0 0 1 1 1 1 Domain of unknown function DUF148 DivIC PF04977.15 KFQ93860.1 - 0.014 15.1 27.8 1.1 9.1 0.1 4.6 2 1 1 4 4 4 0 Septum formation initiator FPP PF05911.11 KFQ93860.1 - 0.014 13.6 22.5 0.024 12.9 22.5 1.3 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil TMF_TATA_bd PF12325.8 KFQ93860.1 - 0.32 11.2 34.9 0.3 11.3 5.0 4.2 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 KFQ93860.1 - 5.8 6.9 40.7 1.6 8.8 13.2 3.4 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KFQ93860.1 - 6.8 5.5 34.3 9.6 5.0 14.7 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KFQ93860.1 - 7.2 6.7 43.4 0.022 14.8 23.4 3.1 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein FHA PF00498.26 KFQ93861.1 - 7.5e-17 61.5 0.0 1.6e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFQ93861.1 - 3.1e-11 43.4 0.0 1e-10 41.7 0.0 2.0 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain ADIP PF11559.8 KFQ93861.1 - 0.0049 17.0 27.5 0.16 12.0 4.7 3.1 1 1 0 2 2 2 1 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 KFQ93861.1 - 0.015 15.3 9.7 0.015 15.3 9.7 4.2 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding Lebercilin PF15619.6 KFQ93861.1 - 0.017 14.8 5.4 0.017 14.8 5.4 3.1 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.10 KFQ93861.1 - 0.08 13.1 11.6 0.54 10.4 0.3 3.0 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family ATG16 PF08614.11 KFQ93861.1 - 0.2 11.8 29.7 3.9 7.6 7.3 3.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GAS PF13851.6 KFQ93861.1 - 0.51 9.6 26.0 2 7.7 3.7 2.5 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding TSC22 PF01166.18 KFQ93861.1 - 0.57 10.5 9.2 2.8 8.3 0.0 3.7 4 0 0 4 4 3 0 TSC-22/dip/bun family FlaC_arch PF05377.11 KFQ93861.1 - 0.68 10.4 14.1 1.3 9.5 0.3 3.9 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Csm1_N PF18504.1 KFQ93861.1 - 0.79 10.1 26.6 2 8.8 0.3 4.9 1 1 3 5 5 5 0 Csm1 N-terminal domain DUF1664 PF07889.12 KFQ93861.1 - 2.4 8.2 13.3 3.6 7.7 0.9 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) PHM7_cyt PF14703.6 KFQ93861.1 - 2.7 8.2 9.2 5 7.3 2.9 2.5 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter OmpH PF03938.14 KFQ93861.1 - 3.2 8.1 28.8 3.6 7.9 5.8 2.7 2 1 1 3 3 2 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 KFQ93861.1 - 3.3 8.4 23.1 6.3 7.5 5.2 4.4 1 1 3 4 4 4 0 SlyX BRE1 PF08647.11 KFQ93861.1 - 4.1 7.6 22.8 3.5 7.8 6.7 2.9 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase DUF2452 PF10504.9 KFQ93861.1 - 4.1 6.8 8.6 0.3 10.5 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2452) Cep57_MT_bd PF06657.13 KFQ93861.1 - 4.8 7.7 15.3 1.9 9.0 1.3 3.4 2 2 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Fez1 PF06818.15 KFQ93861.1 - 6.5 7.2 26.0 3.3 8.1 21.0 2.2 1 1 1 2 2 2 0 Fez1 YlqD PF11068.8 KFQ93861.1 - 6.8 7.1 23.3 6.2 7.2 7.4 3.3 2 1 1 3 3 3 0 YlqD protein HIP1_clath_bdg PF16515.5 KFQ93861.1 - 7.4 7.2 31.0 2.9 8.5 4.6 3.3 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4407 PF14362.6 KFQ93861.1 - 8 5.7 24.2 4.3e+03 -3.3 24.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HAUS-augmin3 PF14932.6 KFQ93861.1 - 9.7 5.7 23.2 0.26 10.8 10.7 2.8 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 3 YqgF PF14639.6 KFQ93862.1 - 0.0032 17.3 0.5 0.004 16.9 0.5 1.3 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 MTD PF01993.18 KFQ93862.1 - 0.028 13.8 0.2 0.034 13.5 0.2 1.1 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase FapA PF03961.13 KFQ93862.1 - 0.31 9.6 6.1 0.36 9.4 6.1 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A EF-hand_1 PF00036.32 KFQ93863.1 - 3.3e-08 32.5 6.5 0.00085 18.7 0.4 2.9 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KFQ93863.1 - 8.7e-06 26.1 1.3 1.4e-05 25.5 0.3 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KFQ93863.1 - 1.9e-05 24.2 1.7 0.011 15.6 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KFQ93863.1 - 0.00069 19.4 2.3 0.0026 17.5 2.2 2.0 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KFQ93863.1 - 0.28 10.8 0.1 0.28 10.8 0.1 2.7 3 0 0 3 3 3 0 EF hand Trypsin PF00089.26 KFQ93864.1 - 1.9e-49 168.4 2.8 1.8e-36 126.0 0.1 2.0 1 1 1 2 2 2 2 Trypsin Trypsin_2 PF13365.6 KFQ93864.1 - 3.1e-07 31.4 0.1 5.9e-07 30.5 0.1 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFQ93864.1 - 0.012 16.0 0.2 0.018 15.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Kelch_1 PF01344.25 KFQ93865.1 - 9.6e-85 278.0 17.8 2e-16 59.3 0.0 6.5 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 KFQ93865.1 - 2.5e-51 170.4 4.9 1.8e-10 40.7 0.0 6.4 2 2 4 6 6 6 6 Kelch motif BACK PF07707.15 KFQ93865.1 - 5.7e-33 113.1 0.2 1.6e-32 111.7 0.2 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 KFQ93865.1 - 1.1e-32 110.7 7.7 1.1e-06 28.4 0.0 6.9 7 0 0 7 7 7 5 Kelch motif Kelch_4 PF13418.6 KFQ93865.1 - 1.2e-31 108.5 7.6 1.4e-07 31.4 0.0 6.3 4 2 2 6 6 6 6 Galactose oxidase, central domain BTB PF00651.31 KFQ93865.1 - 2.5e-28 98.5 1.1 4e-28 97.9 0.4 1.7 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.6 KFQ93865.1 - 6.4e-24 83.7 9.8 1.7e-08 34.6 0.1 6.2 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFQ93865.1 - 3.1e-08 33.4 7.5 0.22 11.6 0.0 6.2 7 0 0 7 7 7 2 Kelch motif Glu_cyclase_2 PF05096.12 KFQ93865.1 - 0.018 14.5 0.0 3 7.2 0.0 2.7 1 1 2 4 4 4 0 Glutamine cyclotransferase PDZ PF00595.24 KFQ93869.1 - 5.5e-49 164.4 4.0 2e-20 72.9 0.4 3.4 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 KFQ93869.1 - 2.9e-25 87.9 1.0 1.2e-08 34.7 0.0 3.4 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 KFQ93869.1 - 1.9e-13 50.5 0.1 0.0011 19.3 0.0 4.0 4 0 0 4 4 4 3 PDZ domain RhoGEF PF00621.20 KFQ93871.1 - 9.2e-34 117.3 0.9 1.4e-33 116.7 0.9 1.3 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 KFQ93871.1 - 1.7e-06 28.5 0.0 1.2e-05 25.8 0.0 2.2 2 0 0 2 2 2 1 PH domain T3SS_needle_E PF08988.10 KFQ93871.1 - 0.1 12.8 2.6 0.77 10.0 0.3 2.6 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle ER-remodelling PF14755.6 KFQ93872.1 - 0.005 17.1 6.4 0.0052 17.1 6.4 1.1 1 0 0 1 1 1 1 Intracellular membrane remodeller SH2 PF00017.24 KFQ93873.1 - 0.005 16.9 0.0 0.0056 16.8 0.0 1.1 1 0 0 1 1 1 1 SH2 domain Aph-1 PF06105.12 KFQ93874.1 - 6.1e-86 287.6 13.0 6.9e-86 287.4 13.0 1.0 1 0 0 1 1 1 1 Aph-1 protein YqfD PF06898.11 KFQ93874.1 - 0.014 14.3 0.5 0.021 13.7 0.5 1.1 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD OST3_OST6 PF04756.13 KFQ93874.1 - 0.24 10.7 6.0 0.07 12.5 1.5 2.0 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Tropomyosin PF00261.20 KFQ93875.1 - 1.7e-69 233.8 44.5 6.1e-66 222.2 30.1 2.0 2 0 0 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 KFQ93875.1 - 6.8e-10 39.3 45.9 0.00024 21.3 7.7 4.3 2 1 0 3 3 3 3 Tropomyosin like Laminin_II PF06009.12 KFQ93875.1 - 5.2e-06 26.5 18.4 0.003 17.6 4.3 3.1 2 1 1 3 3 3 3 Laminin Domain II MscS_porin PF12795.7 KFQ93875.1 - 0.0074 15.9 21.9 0.056 13.0 3.2 2.2 2 0 0 2 2 2 2 Mechanosensitive ion channel porin domain XhlA PF10779.9 KFQ93875.1 - 0.028 14.6 31.8 0.18 12.1 1.4 4.9 2 1 3 5 5 5 0 Haemolysin XhlA TMF_DNA_bd PF12329.8 KFQ93875.1 - 0.069 13.2 39.3 0.097 12.7 8.9 3.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.9 KFQ93875.1 - 0.1 12.9 24.0 0.39 11.0 7.9 3.7 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lebercilin PF15619.6 KFQ93875.1 - 0.11 12.1 37.4 0.97 9.1 5.1 3.1 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 KFQ93875.1 - 0.31 11.1 17.0 0.58 10.2 1.6 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2564 PF10819.8 KFQ93875.1 - 0.33 11.4 7.7 0.81 10.1 0.4 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2564) ERM PF00769.19 KFQ93875.1 - 0.45 10.3 45.4 0.17 11.7 10.3 2.9 1 1 0 2 2 2 0 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.9 KFQ93875.1 - 0.49 10.4 41.3 0.18 11.8 26.8 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Uds1 PF15456.6 KFQ93875.1 - 0.58 10.3 28.2 0.17 12.1 4.5 3.9 2 1 1 3 3 3 0 Up-regulated During Septation TPR_MLP1_2 PF07926.12 KFQ93875.1 - 0.67 10.0 38.2 0.71 9.9 4.9 3.9 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.12 KFQ93875.1 - 0.75 9.8 4.7 3 7.9 0.9 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 KFQ93875.1 - 0.79 8.5 36.6 0.81 8.5 22.3 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein SNARE PF05739.19 KFQ93875.1 - 0.82 9.7 3.6 7.5 6.6 1.3 2.6 2 0 0 2 2 2 0 SNARE domain Sec34 PF04136.15 KFQ93875.1 - 1.2 9.0 11.4 5.7 6.8 0.3 3.1 2 1 0 2 2 2 0 Sec34-like family Alanine_zipper PF11839.8 KFQ93875.1 - 1.6 9.1 19.0 1.6 9.2 2.8 4.3 3 2 1 4 4 4 0 Alanine-zipper, major outer membrane lipoprotein ADIP PF11559.8 KFQ93875.1 - 1.9 8.6 25.7 1.1 9.3 3.6 3.3 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Syntaxin_2 PF14523.6 KFQ93875.1 - 2 8.8 13.9 0.45 10.9 3.1 2.5 2 1 0 2 2 2 0 Syntaxin-like protein KxDL PF10241.9 KFQ93875.1 - 2.2 8.6 15.3 0.13 12.6 2.0 3.5 2 1 1 3 3 3 0 Uncharacterized conserved protein HrpB7 PF09486.10 KFQ93875.1 - 2.3 8.6 25.2 0.3 11.5 2.3 3.7 2 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) Exonuc_VII_L PF02601.15 KFQ93875.1 - 2.3 7.7 19.1 4.9 6.6 11.0 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit CLZ PF16526.5 KFQ93875.1 - 2.6 8.5 26.1 0.61 10.5 0.9 4.2 2 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels T3SSipB PF16535.5 KFQ93875.1 - 2.9 8.3 25.2 0.79 10.2 3.7 3.3 2 1 0 2 2 2 0 Type III cell invasion protein SipB Fez1 PF06818.15 KFQ93875.1 - 3.4 8.1 33.2 3.7 7.9 20.4 2.6 1 1 0 2 2 2 0 Fez1 Spectrin PF00435.21 KFQ93875.1 - 3.5 8.2 29.0 0.13 12.7 3.8 4.0 2 1 2 4 4 4 0 Spectrin repeat Fib_alpha PF08702.10 KFQ93875.1 - 3.6 7.8 19.2 0.32 11.2 3.8 2.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 KFQ93875.1 - 4.4 7.8 25.9 1.7 9.2 6.7 3.9 2 1 1 3 3 3 0 Protein of unknown function DUF16 DUF724 PF05266.14 KFQ93875.1 - 4.9 6.9 35.9 6.1 6.6 4.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF724) DUF745 PF05335.13 KFQ93875.1 - 5.4 6.7 25.8 4.7 6.9 13.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF745) ATG16 PF08614.11 KFQ93875.1 - 6.4 7.0 33.7 3.8 7.7 9.3 3.1 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Laminin_I PF06008.14 KFQ93875.1 - 7.6 6.2 28.5 1 9.0 3.9 2.9 2 1 1 3 3 3 0 Laminin Domain I BRE1 PF08647.11 KFQ93875.1 - 8.5 6.5 32.2 0.99 9.5 12.7 3.4 2 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase EzrA PF06160.12 KFQ93875.1 - 9.1 4.3 34.5 0.88 7.7 5.0 3.1 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA PAP_assoc PF03828.19 KFQ93876.1 - 1.6e-15 57.0 0.0 3.5e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KFQ93876.1 - 6.6e-05 23.1 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain INCA1 PF15142.6 KFQ93877.1 - 0.09 12.8 0.1 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 INCA1 fn3 PF00041.21 KFQ93878.1 - 1.4e-09 38.1 0.0 3.5e-06 27.2 0.0 2.8 2 0 0 2 2 2 2 Fibronectin type III domain SPRY PF00622.28 KFQ93878.1 - 8.8e-07 29.1 0.0 1.9e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 SPRY domain Prenyltransf PF01255.19 KFQ93878.1 - 0.99 8.9 3.6 2.1 7.8 3.6 1.5 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Exonuc_VII_L PF02601.15 KFQ93878.1 - 6.5 6.2 7.6 0.32 10.5 2.0 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tom37 PF10568.9 KFQ93879.1 - 1.4e-34 119.1 0.1 2.2e-34 118.4 0.1 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 KFQ93879.1 - 5.6e-24 83.7 1.1 1.1e-23 82.8 0.3 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KFQ93879.1 - 1.7e-17 64.0 0.0 3e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 KFQ93879.1 - 2.4e-08 33.9 0.0 5.2e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFQ93879.1 - 0.013 15.7 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFQ93879.1 - 0.026 14.7 0.0 0.068 13.4 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TSP_C PF05735.12 KFQ93880.1 - 1.3e-98 328.8 1.5 1.8e-98 328.3 1.5 1.2 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.18 KFQ93880.1 - 3.4e-55 183.4 128.6 2.8e-13 49.3 15.4 9.5 7 2 1 8 8 8 7 Thrombospondin type 3 repeat COMP PF11598.8 KFQ93880.1 - 1.9e-19 69.8 2.5 1.9e-19 69.8 2.5 1.7 2 0 0 2 2 2 1 Cartilage oligomeric matrix protein EGF_CA PF07645.15 KFQ93880.1 - 3.1e-13 49.7 41.5 1.3e-08 34.9 5.7 5.2 3 1 0 4 4 4 2 Calcium-binding EGF domain cEGF PF12662.7 KFQ93880.1 - 1.4e-11 44.1 22.8 0.00011 22.1 0.4 4.6 3 0 0 3 3 3 3 Complement Clr-like EGF-like EGF PF00008.27 KFQ93880.1 - 7.9e-09 35.7 50.9 2.5e-05 24.5 2.7 5.5 4 1 0 4 4 4 3 EGF-like domain EGF_3 PF12947.7 KFQ93880.1 - 7e-05 22.9 14.5 0.0013 18.9 2.9 6.3 5 1 2 7 7 7 3 EGF domain EGF_alliinase PF04863.13 KFQ93880.1 - 0.025 15.0 7.2 0.038 14.4 0.6 3.2 2 0 0 2 2 2 0 Alliinase EGF-like domain KNOX1 PF03790.13 KFQ93880.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 KNOX1 domain Serinc PF03348.15 KFQ93881.1 - 1.8e-163 544.4 34.0 2.1e-163 544.3 34.0 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF5336 PF17270.2 KFQ93881.1 - 0.73 9.5 5.6 1.4 8.5 4.2 2.2 1 1 0 1 1 1 0 Family of unknown function (DUF5336) DUF3593 PF12159.8 KFQ93881.1 - 4.4 7.4 15.8 1.4 9.0 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3593) Pkinase PF00069.25 KFQ93882.1 - 8.6e-70 235.1 0.0 9.9e-70 234.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ93882.1 - 3.9e-28 98.5 0.0 5e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ93882.1 - 4.7e-05 22.8 0.1 0.00044 19.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 KFQ93882.1 - 0.0001 21.5 0.2 0.0014 17.7 0.1 2.1 2 0 0 2 2 2 1 Seadornavirus VP7 APH PF01636.23 KFQ93882.1 - 0.0069 16.3 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFQ93882.1 - 0.019 14.6 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KFQ93882.1 - 0.026 13.4 0.9 0.17 10.8 0.9 2.1 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KFQ93882.1 - 0.083 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase CENP-H PF05837.12 KFQ93883.1 - 1.4e-27 96.3 9.9 1.4e-27 96.3 9.9 2.0 2 0 0 2 2 2 1 Centromere protein H (CENP-H) Host_attach PF10116.9 KFQ93883.1 - 0.03 14.9 1.6 0.23 12.0 0.4 2.1 2 0 0 2 2 2 0 Protein required for attachment to host cells FAM76 PF16046.5 KFQ93883.1 - 1.6 8.0 15.4 2 7.7 15.4 1.1 1 0 0 1 1 1 0 FAM76 protein CorA PF01544.18 KFQ93883.1 - 3.6 6.8 9.4 1 8.6 5.9 1.6 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Cyclin_N PF00134.23 KFQ93884.1 - 5.4e-42 142.5 0.0 2.3e-41 140.5 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFQ93884.1 - 7.7e-35 119.6 1.3 1e-34 119.1 0.7 1.5 2 0 0 2 2 2 1 Cyclin, C-terminal domain Ion_trans PF00520.31 KFQ93885.1 - 2.1e-138 459.4 32.3 1.2e-54 185.2 13.3 4.9 4 1 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 KFQ93885.1 - 3.7e-08 32.5 45.8 8e-08 31.4 12.3 6.0 5 2 1 6 6 6 4 Polycystin cation channel Thionin PF00321.17 KFQ93886.1 - 3.7 8.1 36.2 1.6 9.3 1.6 5.8 3 3 3 6 6 6 0 Plant thionin O-FucT PF10250.9 KFQ93887.1 - 5.6e-73 246.6 0.0 6.5e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase MCM3AP_GANP PF16769.5 KFQ93888.1 - 0 1126.9 3.2 0 1126.9 3.2 1.6 2 0 0 2 2 2 1 MCM3AP domain of GANP SAC3_GANP PF03399.16 KFQ93888.1 - 1.8e-117 391.9 4.4 1.8e-117 391.9 4.4 1.9 2 0 0 2 2 2 1 SAC3/GANP family CID_GANP PF16766.5 KFQ93888.1 - 1.2e-28 99.1 11.8 1.4e-28 98.9 5.4 3.0 2 0 0 2 2 2 1 Binding region of GANP to ENY2 CSN8_PSD8_EIF3K PF10075.9 KFQ93888.1 - 4.2e-06 26.8 0.0 1.2e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Tobravirus_2B PF05271.11 KFQ93888.1 - 0.019 14.9 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 Tobravirus 2B protein RRM_1 PF00076.22 KFQ93888.1 - 0.11 12.4 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NleF_casp_inhib PF16809.5 KFQ93888.1 - 0.21 11.5 0.9 9.1 6.2 0.8 2.5 2 0 0 2 2 2 0 NleF caspase inhibitor CNOT11 PF10155.9 KFQ93888.1 - 0.25 11.5 2.0 0.72 10.0 2.0 1.8 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 11 Keratin PF02422.16 KFQ93889.1 - 1e-32 111.7 9.2 1.2e-32 111.5 9.2 1.0 1 0 0 1 1 1 1 Keratin FTCD_N PF07837.12 KFQ93890.1 - 6.4e-72 241.0 0.0 1e-71 240.4 0.0 1.3 1 0 0 1 1 1 1 Formiminotransferase domain, N-terminal subdomain FTCD PF02971.14 KFQ93890.1 - 5.7e-68 227.5 0.0 1e-67 226.6 0.0 1.5 1 0 0 1 1 1 1 Formiminotransferase domain FTCD_C PF04961.12 KFQ93890.1 - 2.9e-66 222.7 0.5 4.1e-66 222.2 0.5 1.2 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase VWA PF00092.28 KFQ93891.1 - 5.9e-85 283.9 5.2 1.1e-28 100.6 0.1 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain Collagen PF01391.18 KFQ93891.1 - 8.8e-52 172.7 202.9 8.9e-10 38.2 25.0 7.3 1 1 4 5 5 5 3 Collagen triple helix repeat (20 copies) VWA_2 PF13519.6 KFQ93891.1 - 8.8e-37 126.0 0.7 1.3e-12 48.3 0.0 3.3 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA PF00092.28 KFQ93892.1 - 2.5e-82 275.4 1.8 2.8e-26 92.8 0.0 3.5 3 1 0 3 3 3 3 von Willebrand factor type A domain Collagen PF01391.18 KFQ93892.1 - 7.3e-52 173.0 206.2 3.1e-09 36.4 24.4 7.2 1 1 6 7 7 7 7 Collagen triple helix repeat (20 copies) VWA_2 PF13519.6 KFQ93892.1 - 1.4e-41 141.4 4.0 2e-18 67.0 0.1 3.7 3 1 0 3 3 3 3 von Willebrand factor type A domain VWA_3 PF13768.6 KFQ93892.1 - 4.8e-07 29.8 0.1 9e-05 22.4 0.1 3.4 3 1 0 3 3 3 1 von Willebrand factor type A domain DUF1194 PF06707.11 KFQ93892.1 - 1.2e-06 27.9 2.6 0.0019 17.4 0.9 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF1194) VWA_CoxE PF05762.14 KFQ93892.1 - 2.4e-05 23.8 0.3 0.0059 16.0 0.0 2.7 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 KFQ93892.1 - 0.039 14.1 0.2 0.099 12.7 0.2 1.6 1 0 0 1 1 1 0 vWA found in TerF C terminus Piwi PF02171.17 KFQ93892.1 - 0.13 11.4 0.2 0.21 10.8 0.2 1.2 1 0 0 1 1 1 0 Piwi domain DUF5507 PF17612.2 KFQ93892.1 - 0.14 11.8 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5507) KH_1 PF00013.29 KFQ93893.1 - 1.5e-45 152.8 13.4 4.4e-19 68.1 0.4 4.1 4 0 0 4 4 4 3 KH domain KH_2 PF07650.17 KFQ93893.1 - 3.9e-11 42.6 1.2 5.5e-06 26.1 0.0 2.8 3 0 0 3 3 3 2 KH domain KH_4 PF13083.6 KFQ93893.1 - 7.7e-06 25.7 1.1 1.1 9.2 0.0 3.5 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 KFQ93893.1 - 0.00055 19.9 0.0 0.024 14.6 0.0 2.4 2 0 0 2 2 2 1 KH-like RNA-binding domain KH_5 PF13184.6 KFQ93893.1 - 0.00091 19.3 5.0 0.32 11.1 0.2 2.7 3 0 0 3 3 3 2 NusA-like KH domain DUF370 PF04025.12 KFQ93893.1 - 0.15 12.2 0.3 0.83 9.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF370) Folate_carrier PF01770.18 KFQ93894.1 - 2.6e-158 527.1 35.0 2.7e-83 280.0 15.8 2.0 1 1 1 2 2 2 2 Reduced folate carrier MFS_1 PF07690.16 KFQ93894.1 - 1.7e-08 33.8 35.2 1.7e-08 33.8 35.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Endostatin PF06482.11 KFQ93895.1 - 1.6e-109 366.2 0.0 2.1e-109 365.9 0.0 1.1 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin Collagen PF01391.18 KFQ93895.1 - 3.6e-66 218.8 336.5 1e-08 34.8 16.1 15.9 9 3 4 13 13 13 12 Collagen triple helix repeat (20 copies) Laminin_G_3 PF13385.6 KFQ93895.1 - 0.00011 22.3 0.0 0.00018 21.7 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF1554 PF07588.11 KFQ93895.1 - 0.25 11.2 0.1 1.7 8.5 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1554) PAS_3 PF08447.12 KFQ93896.1 - 2e-17 63.3 0.4 3.5e-12 46.4 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KFQ93896.1 - 4.2e-12 46.2 0.1 6.1e-10 39.2 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KFQ93896.1 - 6.7e-12 45.4 0.0 1.1e-10 41.5 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 KFQ93896.1 - 0.00056 20.1 0.0 0.088 13.1 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 KFQ93896.1 - 0.09 13.0 0.0 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 PAS fold PAS_3 PF08447.12 KFQ93897.1 - 7.9e-19 67.7 0.1 5.5e-13 49.0 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KFQ93897.1 - 1.5e-12 47.6 0.0 1.8e-10 40.9 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KFQ93897.1 - 1.2e-08 34.9 0.0 3.6e-07 30.2 0.0 2.4 2 0 0 2 2 2 1 PAS fold HLH PF00010.26 KFQ93897.1 - 1.5e-06 28.0 0.5 3.9e-06 26.7 0.1 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 KFQ93897.1 - 0.0045 17.2 0.0 0.1 12.9 0.0 2.4 2 0 0 2 2 2 1 PAS domain dNK PF01712.19 KFQ93898.1 - 8.1e-34 117.3 0.0 1e-33 116.9 0.0 1.1 1 0 0 1 1 1 1 Deoxynucleoside kinase SKI PF01202.22 KFQ93898.1 - 0.0014 18.7 0.1 0.2 11.8 0.1 2.4 2 0 0 2 2 2 1 Shikimate kinase Thymidylate_kin PF02223.17 KFQ93898.1 - 0.0037 17.0 0.5 0.01 15.5 0.2 1.9 2 1 0 2 2 2 1 Thymidylate kinase TsaE PF02367.17 KFQ93898.1 - 0.053 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 KFQ93898.1 - 0.078 13.4 0.0 6.8 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 KFQ93898.1 - 0.18 11.5 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase Hist_deacetyl PF00850.19 KFQ93899.1 - 8.7e-84 281.6 8.3 1.3e-83 281.0 0.0 2.5 2 0 0 2 2 2 1 Histone deacetylase domain HDAC4_Gln PF12203.8 KFQ93899.1 - 8e-35 118.9 46.0 8e-35 118.9 46.0 3.5 2 1 1 3 3 3 1 Glutamine rich N terminal domain of histone deacetylase 4 HLH PF00010.26 KFQ93900.1 - 1.4e-15 56.9 0.6 3e-15 55.9 0.6 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_51 PF18558.1 KFQ93900.1 - 0.0033 17.3 0.0 0.005 16.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain DUF773 PF05600.12 KFQ93900.1 - 0.019 13.7 0.8 0.023 13.4 0.8 1.1 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 GDH_N PF12466.8 KFQ93900.1 - 0.05 13.8 0.1 0.076 13.2 0.1 1.3 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal L27 PF02828.16 KFQ93900.1 - 0.1 12.4 0.3 5.5 6.8 0.0 2.5 2 0 0 2 2 2 0 L27 domain Ank_2 PF12796.7 KFQ93901.1 - 2e-23 82.8 0.0 2e-12 47.5 0.0 3.7 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFQ93901.1 - 9.2e-19 65.6 4.2 0.00081 19.7 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KFQ93901.1 - 2.3e-18 65.7 5.0 0.00034 20.9 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 KFQ93901.1 - 3.6e-15 55.8 1.3 3.3e-05 24.1 0.1 4.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFQ93901.1 - 6.5e-14 52.1 0.9 2.7e-07 31.0 0.0 4.7 2 2 1 4 4 4 3 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFQ93901.1 - 9.8e-08 32.2 4.3 2.2e-07 31.1 4.3 1.5 1 0 0 1 1 1 1 SOCS box HEAT PF02985.22 KFQ93902.1 - 1e-05 25.3 4.1 1.2 9.6 0.0 5.9 6 0 0 6 6 6 1 HEAT repeat Dopey_N PF04118.14 KFQ93902.1 - 6.8e-05 22.1 0.2 0.00013 21.2 0.2 1.5 1 1 0 1 1 1 1 Dopey, N-terminal Tti2 PF10521.9 KFQ93902.1 - 0.00097 18.8 0.2 0.015 14.8 0.0 2.3 1 1 1 2 2 2 1 Tti2 family Cnd1 PF12717.7 KFQ93902.1 - 0.0019 18.2 2.0 0.07 13.2 0.4 2.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 MOR2-PAG1_C PF14225.6 KFQ93902.1 - 0.002 18.0 3.4 0.72 9.7 0.3 2.4 1 1 1 2 2 2 2 Cell morphogenesis C-terminal Adaptin_N PF01602.20 KFQ93902.1 - 0.0064 15.1 1.0 0.02 13.5 1.0 1.8 1 1 0 1 1 1 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 KFQ93902.1 - 0.019 15.6 0.0 0.3 11.7 0.0 2.9 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KFQ93902.1 - 0.028 14.9 3.0 16 6.1 0.5 3.8 3 0 0 3 3 3 0 HEAT-like repeat V-ATPase_H_C PF11698.8 KFQ93902.1 - 0.11 12.6 0.3 1.6 8.8 0.0 3.0 4 0 0 4 4 4 0 V-ATPase subunit H Arm_2 PF04826.13 KFQ93902.1 - 0.14 11.6 1.1 0.21 11.0 0.1 1.8 2 0 0 2 2 2 0 Armadillo-like fn3 PF00041.21 KFQ93903.1 - 3e-71 235.8 3.8 1.2e-11 44.8 0.1 6.3 6 0 0 6 6 6 6 Fibronectin type III domain DUF4945 PF16303.5 KFQ93903.1 - 8.4e-06 25.7 0.0 6.5 6.7 0.0 4.0 4 0 0 4 4 4 3 Domain of unknown function (DUF4945) DUF2369 PF10179.9 KFQ93903.1 - 5.3e-05 23.5 0.0 7.2 7.1 0.0 4.9 5 0 0 5 5 5 1 Uncharacterised conserved protein (DUF2369) DUF4998 PF16389.5 KFQ93903.1 - 0.00022 20.9 0.0 22 4.6 0.0 4.1 4 0 0 4 4 4 2 Domain of unknown function OB_aCoA_assoc PF01796.17 KFQ93903.1 - 0.0032 17.4 11.1 11 6.1 0.0 6.2 6 1 1 7 7 7 1 DUF35 OB-fold domain, acyl-CoA-associated OAF PF14941.6 KFQ93903.1 - 0.1 12.0 0.0 77 2.6 0.0 3.1 3 0 0 3 3 3 0 Transcriptional regulator, Out at first MBD_C PF14048.6 KFQ93903.1 - 3.8 8.3 4.4 2e+02 2.8 0.1 3.4 3 0 0 3 3 3 0 C-terminal domain of methyl-CpG binding protein 2 and 3 MHC_I PF00129.18 KFQ93904.1 - 1.7e-33 115.7 0.4 1.8e-33 115.6 0.4 1.0 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 MHC_I_3 PF16497.5 KFQ93904.1 - 7.3e-05 22.3 0.0 9.2e-05 22.0 0.0 1.0 1 0 0 1 1 1 1 MHC-I family domain 7tm_4 PF13853.6 KFQ93905.1 - 1.4e-56 192.3 14.8 1.8e-56 191.9 14.8 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ93905.1 - 7.6e-30 104.1 18.8 9.8e-30 103.8 18.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RVT_1 PF00078.27 KFQ93906.1 - 0.2 11.2 0.0 0.39 10.2 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) TMEM214 PF10151.9 KFQ93908.1 - 2.7e-48 164.9 0.1 3e-48 164.8 0.1 1.0 1 0 0 1 1 1 1 TMEM214, C-terminal, caspase 4 activator WD40 PF00400.32 KFQ93909.1 - 2.8e-06 28.0 5.9 0.0051 17.6 0.5 3.2 3 1 0 3 3 3 2 WD domain, G-beta repeat LT-IIB PF06453.11 KFQ93909.1 - 0.089 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) Cation_efflux PF01545.21 KFQ93910.1 - 1.4e-15 57.6 0.0 1.8e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KFQ93910.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter PRK PF00485.18 KFQ93911.1 - 5e-56 189.6 0.0 5.7e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KFQ93911.1 - 1.3e-05 25.8 0.0 1.8e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 KFQ93911.1 - 3.1e-05 23.9 0.0 5.2e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 KFQ93911.1 - 6.7e-05 23.1 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KFQ93911.1 - 0.0038 17.7 0.0 0.91 9.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain CoaE PF01121.20 KFQ93911.1 - 0.0054 16.4 0.1 0.46 10.1 0.0 2.2 2 0 0 2 2 2 1 Dephospho-CoA kinase CbiA PF01656.23 KFQ93911.1 - 0.064 13.3 0.2 0.76 9.8 0.2 2.2 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Cytidylate_kin PF02224.18 KFQ93911.1 - 0.065 13.0 0.1 5.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase Mpv17_PMP22 PF04117.12 KFQ93912.1 - 2e-18 66.4 1.2 2.7e-18 65.9 1.2 1.2 1 0 0 1 1 1 1 Mpv17 / PMP22 family CPSase_L_D2 PF02786.17 KFQ93913.1 - 8.4e-70 234.5 1.4 2.5e-29 102.3 0.0 3.4 2 1 1 3 3 3 3 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KFQ93913.1 - 8.4e-40 135.9 0.2 2.8e-39 134.2 0.1 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain GATase PF00117.28 KFQ93913.1 - 7.5e-38 130.2 0.0 1.9e-37 128.9 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 KFQ93913.1 - 3.5e-29 101.7 0.1 7.4e-29 100.7 0.1 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 KFQ93913.1 - 9.4e-20 71.3 0.0 2.7e-19 69.8 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 KFQ93913.1 - 1.2e-18 67.1 0.0 8.9e-18 64.3 0.0 2.4 2 0 0 2 2 2 1 MGS-like domain Amidohydro_1 PF01979.20 KFQ93913.1 - 5.1e-12 45.8 0.1 5.5e-09 35.8 0.1 3.4 3 1 0 3 3 3 2 Amidohydrolase family ATPgrasp_Ter PF15632.6 KFQ93913.1 - 8.6e-12 44.9 0.1 0.00014 21.6 0.0 3.1 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 KFQ93913.1 - 2.2e-08 33.9 0.1 6.3e-06 25.9 0.0 2.7 1 1 1 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFQ93913.1 - 3.8e-06 26.6 0.4 0.063 12.9 0.0 2.6 2 1 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 KFQ93913.1 - 0.00011 22.1 8.0 0.00012 22.0 0.4 3.4 3 1 0 3 3 3 1 Peptidase C26 ATP-grasp_3 PF02655.14 KFQ93913.1 - 0.0023 18.0 0.2 0.18 11.9 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain IBR PF01485.21 KFQ93914.1 - 1.1e-19 70.4 27.2 6.9e-13 48.6 11.6 4.6 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KFQ93914.1 - 0.022 15.1 7.0 0.022 15.1 7.0 4.9 4 2 1 5 5 5 0 Ring finger domain Radical_SAM PF04055.21 KFQ93915.1 - 1.4e-15 58.1 0.1 3.5e-15 56.8 0.1 1.7 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 KFQ93915.1 - 1.3e-08 35.0 0.8 7.4e-07 29.3 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_12 PF13353.6 KFQ93915.1 - 2.1e-08 34.6 0.7 3.7e-08 33.7 0.5 1.6 1 1 0 1 1 1 1 4Fe-4S single cluster domain Thymidylate_kin PF02223.17 KFQ93916.1 - 1.1e-09 38.3 0.3 7e-09 35.6 0.3 2.1 1 1 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.6 KFQ93916.1 - 0.00078 19.6 0.0 0.00094 19.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain PPK2 PF03976.14 KFQ93916.1 - 0.013 15.1 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) AAA_16 PF13191.6 KFQ93916.1 - 0.061 13.7 0.0 0.1 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain HMG_box PF00505.19 KFQ93918.1 - 4.4e-27 94.3 1.9 7.7e-26 90.3 3.5 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFQ93918.1 - 1.2e-08 35.5 0.6 2.7e-08 34.3 0.6 1.6 1 0 0 1 1 1 1 HMG-box domain PRR22 PF15776.5 KFQ93919.1 - 8e-05 22.2 4.6 0.011 15.2 0.0 2.1 1 1 1 2 2 2 2 Proline-rich protein family 22 Lectin_C PF00059.21 KFQ93921.1 - 1.5e-17 64.3 0.0 2.3e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain Collagen PF01391.18 KFQ93921.1 - 1.4e-14 53.6 51.8 2.7e-09 36.6 23.9 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Ribosomal_S7e PF01251.18 KFQ93922.1 - 4.5e-94 313.4 4.1 5.1e-94 313.2 4.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e RNase_H PF00075.24 KFQ93923.1 - 1.7e-46 158.0 0.0 2.3e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KFQ93923.1 - 0.00034 20.4 0.0 0.0007 19.4 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase-like MafB19-deam PF14437.6 KFQ93923.1 - 0.048 13.4 0.1 0.088 12.6 0.1 1.5 1 1 0 1 1 1 0 MafB19-like deaminase ARD PF03079.14 KFQ93924.1 - 2.3e-48 164.3 0.3 2.6e-48 164.2 0.3 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KFQ93924.1 - 1.2e-08 34.6 0.0 1.6e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KFQ93924.1 - 1.7e-05 24.7 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_8 PF13621.6 KFQ93924.1 - 0.0057 16.4 0.0 0.061 13.0 0.0 2.0 1 1 0 1 1 1 1 Cupin-like domain Cupin_1 PF00190.22 KFQ93924.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.12 KFQ93924.1 - 0.052 13.2 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) TPR_2 PF07719.17 KFQ93925.1 - 4.3e-12 45.2 0.0 0.0047 16.9 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ93925.1 - 8.7e-12 44.3 0.0 0.0024 17.6 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ93925.1 - 2.3e-08 34.2 0.4 0.00024 21.3 0.0 3.8 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ93925.1 - 1.5e-06 28.6 0.2 0.031 14.8 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ93925.1 - 1.4e-05 25.6 0.0 0.034 14.8 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFQ93925.1 - 2.6e-05 24.5 0.1 0.0041 17.7 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ93925.1 - 0.0018 18.5 2.0 0.6 10.6 0.2 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ93925.1 - 0.0031 17.6 0.0 4.6 7.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Coatomer_E PF04733.14 KFQ93925.1 - 0.008 15.6 0.1 0.019 14.4 0.1 1.6 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_14 PF13428.6 KFQ93925.1 - 0.061 14.2 0.0 42 5.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ93925.1 - 0.1 12.6 0.0 11 6.3 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ93925.1 - 0.18 12.1 1.2 3.3 8.0 0.1 2.8 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 WD40 PF00400.32 KFQ93926.1 - 2.7e-16 59.7 7.7 1.5e-05 25.7 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Lectin_C PF00059.21 KFQ93927.1 - 0.00099 19.8 4.3 0.00099 19.8 4.3 2.1 2 1 0 2 2 2 1 Lectin C-type domain Mpv17_PMP22 PF04117.12 KFQ93927.1 - 0.016 15.4 0.2 0.033 14.4 0.2 1.5 1 0 0 1 1 1 0 Mpv17 / PMP22 family Spc7 PF08317.11 KFQ93927.1 - 0.17 10.8 2.5 0.24 10.3 2.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Chordopox_A33R PF05966.12 KFQ93927.1 - 0.2 10.9 2.1 0.29 10.4 0.3 1.9 2 0 0 2 2 2 0 Chordopoxvirus A33R protein Ly49 PF08391.10 KFQ93927.1 - 0.22 11.9 3.0 0.24 11.7 0.3 2.2 2 1 0 2 2 2 0 Ly49-like protein, N-terminal region Val_tRNA-synt_C PF10458.9 KFQ93927.1 - 0.24 11.7 0.1 0.24 11.7 0.1 1.8 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm YgaB PF14182.6 KFQ93927.1 - 0.29 11.6 1.5 11 6.4 0.4 2.3 1 1 1 2 2 2 0 YgaB-like protein SlyX PF04102.12 KFQ93927.1 - 4.6 7.9 6.4 4.8 7.9 3.3 2.1 1 1 1 2 2 2 0 SlyX Pkinase_Tyr PF07714.17 KFQ93928.1 - 4.3e-23 81.9 0.0 7.5e-22 77.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ93928.1 - 6.4e-19 68.3 0.0 1e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KFQ93928.1 - 0.0085 15.5 0.0 0.022 14.1 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C2H2 PF00096.26 KFQ93929.1 - 1.1e-41 138.9 43.5 6.8e-08 32.6 1.5 7.1 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ93929.1 - 7.5e-33 111.5 36.3 6.9e-09 35.7 0.1 7.3 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ93929.1 - 1.5e-23 81.4 41.9 0.00014 22.4 0.9 7.1 7 0 0 7 7 7 6 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFQ93929.1 - 1.7e-09 37.6 18.2 0.00058 19.9 0.5 4.7 2 1 4 6 6 6 3 Zinc ribbon domain zf-C2H2_jaz PF12171.8 KFQ93929.1 - 1.9e-07 31.2 13.1 0.77 10.1 0.0 6.0 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFQ93929.1 - 8.2e-07 28.9 39.0 0.0054 16.7 2.4 6.9 6 1 0 6 6 6 2 C2H2-type zinc finger zf-LYAR PF08790.11 KFQ93929.1 - 9.5e-07 28.6 13.0 0.55 10.2 0.3 5.5 5 0 0 5 5 5 3 LYAR-type C2HC zinc finger DZR PF12773.7 KFQ93929.1 - 1.2e-06 28.4 23.8 0.0078 16.2 0.5 3.6 2 1 0 2 2 2 1 Double zinc ribbon zf_UBZ PF18439.1 KFQ93929.1 - 2.1e-06 27.2 23.5 0.72 9.5 0.1 6.5 7 0 0 7 7 7 4 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 KFQ93929.1 - 5e-06 26.2 31.5 0.0079 15.9 0.2 5.9 6 0 0 6 6 6 3 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 KFQ93929.1 - 6.1e-06 26.9 14.2 0.017 15.9 0.5 3.1 2 1 1 3 3 3 3 zinc-ribbon family XPA_N PF01286.18 KFQ93929.1 - 1.3e-05 25.2 18.1 2.5 8.2 0.0 6.2 6 1 0 6 6 6 3 XPA protein N-terminal FYDLN_acid PF09538.10 KFQ93929.1 - 0.00012 22.7 10.7 6.2 7.6 0.0 5.6 1 1 5 6 6 6 0 Protein of unknown function (FYDLN_acid) DNA_RNApol_7kD PF03604.13 KFQ93929.1 - 0.00025 20.6 23.5 1 9.1 0.1 6.2 6 0 0 6 6 6 2 DNA directed RNA polymerase, 7 kDa subunit zf-Di19 PF05605.12 KFQ93929.1 - 0.0023 18.2 16.7 0.45 10.9 0.8 3.8 2 1 2 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding ADK_lid PF05191.14 KFQ93929.1 - 0.0032 17.4 13.3 3.9 7.5 1.2 5.2 1 1 3 4 4 4 1 Adenylate kinase, active site lid zf_C2H2_ZHX PF18387.1 KFQ93929.1 - 0.0072 15.9 22.5 0.96 9.1 0.4 5.7 1 1 5 6 6 6 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-trcl PF13451.6 KFQ93929.1 - 0.0074 16.2 22.0 0.7 9.8 0.0 5.7 4 1 1 5 5 5 1 Probable zinc-ribbon domain CpXC PF14353.6 KFQ93929.1 - 0.0075 16.3 16.5 5.3 7.1 0.2 5.7 2 1 4 6 6 6 1 CpXC protein C1_4 PF07975.12 KFQ93929.1 - 0.012 15.9 14.6 0.19 12.0 0.6 3.5 2 2 0 3 3 3 0 TFIIH C1-like domain Zn_ribbon_recom PF13408.6 KFQ93929.1 - 0.031 14.8 26.4 3.5 8.2 0.5 5.5 3 2 2 5 5 5 0 Recombinase zinc beta ribbon domain DUF2256 PF10013.9 KFQ93929.1 - 0.071 13.2 14.5 18 5.6 0.0 5.8 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) HypA PF01155.19 KFQ93929.1 - 0.088 12.8 16.7 0.74 9.9 0.7 3.7 1 1 3 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-H2C2_5 PF13909.6 KFQ93929.1 - 0.091 12.5 0.1 0.091 12.5 0.1 7.7 8 1 0 8 8 8 0 C2H2-type zinc-finger domain DUF3268 PF11672.8 KFQ93929.1 - 0.12 12.7 12.9 1.4 9.3 1.0 3.2 2 1 2 4 4 4 0 zinc-finger-containing domain zinc_ribbon_9 PF14369.6 KFQ93929.1 - 0.19 12.0 18.6 6.1 7.2 0.6 5.7 6 0 0 6 6 6 0 zinc-ribbon GAGA PF09237.11 KFQ93929.1 - 0.3 10.9 0.0 0.3 10.9 0.0 4.7 1 1 5 6 6 6 0 GAGA factor YhfH PF14149.6 KFQ93929.1 - 3.9 7.5 24.1 18 5.4 0.1 6.0 6 0 0 6 6 6 0 YhfH-like protein LIM PF00412.22 KFQ93929.1 - 4.4 7.6 20.4 8.6 6.7 1.0 4.2 2 1 2 4 4 4 0 LIM domain DUF2321 PF10083.9 KFQ93929.1 - 5.8 6.5 14.1 2.2 7.9 0.9 3.9 1 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2321) Peptidase_C50 PF03568.17 KFQ93930.1 - 6e-29 101.4 0.2 5.9e-15 55.3 0.0 2.5 2 0 0 2 2 2 2 Peptidase family C50 TPR_12 PF13424.6 KFQ93930.1 - 0.012 15.8 4.3 0.012 15.8 0.4 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat HTH_20 PF12840.7 KFQ93930.1 - 0.6 10.2 3.9 0.81 9.8 0.4 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain MFS_5 PF05631.14 KFQ93931.1 - 2.6e-82 276.6 3.2 3.1e-82 276.3 3.2 1.0 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 KFQ93931.1 - 3e-11 42.9 15.1 7.5e-11 41.6 15.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFQ93931.1 - 0.00029 19.8 0.4 0.00029 19.8 0.4 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KFQ93931.1 - 0.00089 18.2 2.4 0.0032 16.4 0.1 2.2 2 1 0 2 2 2 1 MFS_1 like family UNC-93 PF05978.16 KFQ93931.1 - 0.019 14.7 1.2 0.024 14.4 0.3 1.6 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 Glyco_hydro_31 PF01055.26 KFQ93932.1 - 2.8e-272 903.4 8.4 1.2e-147 492.7 2.5 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KFQ93932.1 - 2.4e-53 179.3 0.2 1.4e-28 99.4 0.3 2.6 3 0 0 3 3 3 2 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 KFQ93932.1 - 3.8e-12 45.9 15.4 4.3e-07 29.7 1.7 3.0 3 0 0 3 3 3 2 Trefoil (P-type) domain Gal_mutarotas_2 PF13802.6 KFQ93932.1 - 5.6e-10 39.4 5.5 0.0001 22.6 1.3 2.9 2 0 0 2 2 2 2 Galactose mutarotase-like Tmemb_40 PF10160.9 KFQ93932.1 - 0.23 10.9 0.1 1.7 8.1 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein SPARC_Ca_bdg PF10591.9 KFQ93933.1 - 1.2e-32 112.5 0.4 2.4e-32 111.6 0.4 1.5 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Thyroglobulin_1 PF00086.18 KFQ93933.1 - 6.3e-19 67.4 5.4 6.3e-19 67.4 5.4 2.5 2 1 0 2 2 2 1 Thyroglobulin type-1 repeat Kazal_2 PF07648.15 KFQ93933.1 - 7.9e-11 41.9 7.9 2e-10 40.6 7.9 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFQ93933.1 - 0.00018 21.4 6.3 0.00018 21.4 6.3 2.2 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.6 KFQ93933.1 - 0.084 13.3 1.4 0.9 10.0 0.1 3.0 3 1 1 4 4 4 0 EF-hand domain pair Kelch_1 PF01344.25 KFQ93934.1 - 2.6e-82 270.2 22.2 2.3e-16 59.1 0.6 6.5 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 KFQ93934.1 - 1.8e-38 129.6 2.8 7.9e-06 26.0 0.1 6.4 4 2 2 6 6 6 6 Kelch motif BACK PF07707.15 KFQ93934.1 - 7.1e-37 125.6 1.0 2e-36 124.2 1.0 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 KFQ93934.1 - 3e-32 111.2 0.8 6.7e-32 110.0 0.8 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.6 KFQ93934.1 - 1.2e-29 102.0 13.1 6.9e-05 23.0 0.2 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 KFQ93934.1 - 1.7e-27 94.3 6.1 8e-05 22.5 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 KFQ93934.1 - 7.9e-21 73.8 4.3 0.00041 20.3 0.0 6.3 4 1 2 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 KFQ93934.1 - 0.00016 21.6 13.4 3.3 7.8 0.2 5.3 5 0 0 5 5 5 3 Kelch motif Skp1_POZ PF03931.15 KFQ93934.1 - 0.0066 16.6 0.2 0.039 14.1 0.0 2.1 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF3342 PF11822.8 KFQ93934.1 - 0.16 12.2 0.9 0.96 9.7 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3342) PQQ_3 PF13570.6 KFQ93934.1 - 3.3 8.3 12.7 16 6.1 0.1 4.9 5 0 0 5 5 5 0 PQQ-like domain 7tm_1 PF00001.21 KFQ93935.1 - 2.4e-51 174.6 22.1 2.4e-51 174.6 22.1 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFQ93935.1 - 1.4e-06 28.1 19.0 1.4e-06 28.1 19.0 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFQ93935.1 - 2.2e-06 27.2 21.6 1.2e-05 24.8 21.6 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 KFQ93935.1 - 0.016 14.5 27.5 0.14 11.4 27.5 2.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Adipogenin PF15202.6 KFQ93935.1 - 0.36 10.9 7.3 2.3 8.3 0.1 3.6 3 0 0 3 3 3 0 Adipogenin Laminin_G_1 PF00054.23 KFQ93936.1 - 1.5e-79 264.6 0.0 1.6e-26 93.1 0.0 3.2 3 0 0 3 3 3 3 Laminin G domain Laminin_G_2 PF02210.24 KFQ93936.1 - 1.3e-78 261.7 0.1 9.1e-26 90.9 0.0 3.4 3 0 0 3 3 3 3 Laminin G domain fn3 PF00041.21 KFQ93936.1 - 1.1e-22 80.1 0.2 2.3e-12 47.1 0.2 2.6 2 0 0 2 2 2 2 Fibronectin type III domain Laminin_G_3 PF13385.6 KFQ93936.1 - 6.9e-11 42.5 0.1 0.025 14.7 0.0 3.3 3 0 0 3 3 3 3 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 KFQ93936.1 - 1.6e-09 37.8 40.7 1.5e-07 31.6 7.2 3.9 4 0 0 4 4 4 2 EGF-like domain Stirrup PF09061.6 KFQ93936.1 - 3.8e-07 30.2 0.1 0.013 15.7 0.0 3.4 3 0 0 3 3 3 2 Stirrup hEGF PF12661.7 KFQ93936.1 - 1.4e-06 28.7 12.6 0.0001 22.8 3.9 4.1 4 0 0 4 4 4 2 Human growth factor-like EGF Pur_ac_phosph_N PF16656.5 KFQ93936.1 - 2.3e-06 28.1 0.0 0.02 15.4 0.1 2.6 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain fn3_4 PF16794.5 KFQ93936.1 - 0.0032 17.3 0.0 0.48 10.4 0.1 2.4 2 0 0 2 2 2 1 Fibronectin-III type domain EGF_CA PF07645.15 KFQ93936.1 - 9.3 6.5 38.8 0.79 10.0 5.5 3.5 3 0 0 3 3 3 0 Calcium-binding EGF domain hSH3 PF14603.6 KFQ93937.1 - 1.6e-07 31.6 7.3 1e-06 29.1 0.1 3.5 3 1 0 3 3 3 1 Helically-extended SH3 domain SH3_2 PF07653.17 KFQ93937.1 - 1.5e-05 24.6 0.0 2.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFQ93937.1 - 0.029 14.0 0.0 0.059 13.0 0.0 1.5 1 0 0 1 1 1 0 SH3 domain CDC45 PF02724.14 KFQ93937.1 - 7.5 4.7 8.8 10 4.3 8.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S49_N PF08496.10 KFQ93937.1 - 9 6.3 8.5 20 5.2 8.5 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal HSP20 PF00011.21 KFQ93938.1 - 1.1e-15 57.5 0.1 2.2e-15 56.6 0.0 1.5 2 0 0 2 2 2 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KFQ93938.1 - 0.0053 16.3 0.0 0.0077 15.8 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA HrpB1_HrpK PF09613.10 KFQ93938.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) Arrestin_N PF00339.29 KFQ93939.1 - 1.2e-35 122.7 0.0 4.5e-34 117.6 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KFQ93939.1 - 2.5e-25 89.5 0.0 2.8e-21 76.4 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.15 KFQ93939.1 - 0.0017 17.4 0.1 0.01 14.8 0.1 2.2 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 7tm_1 PF00001.21 KFQ93942.1 - 8.8e-56 189.1 17.5 1.3e-55 188.6 17.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFQ93942.1 - 4.1e-05 23.5 16.5 7.3e-05 22.6 16.5 1.4 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KFQ93942.1 - 0.00021 20.8 24.2 0.0093 15.4 5.9 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx zf-C2H2 PF00096.26 KFQ93943.1 - 6.5e-11 42.1 32.8 0.0036 17.7 1.8 7.2 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-met PF12874.7 KFQ93943.1 - 4.9e-08 33.1 18.9 0.0045 17.3 0.1 5.6 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFQ93943.1 - 2.4e-07 31.0 35.8 0.0066 17.2 1.1 7.5 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ93943.1 - 8.8e-06 25.9 14.7 0.091 13.1 0.6 4.9 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 KFQ93943.1 - 0.039 14.1 9.9 0.2 11.8 0.3 3.7 3 0 0 3 3 3 0 Aberrant zinc-finger DUF5472 PF17566.2 KFQ93943.1 - 0.89 9.6 6.0 37 4.4 0.1 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5472) zf-BED PF02892.15 KFQ93943.1 - 9.8 6.3 19.2 0.35 10.9 2.2 3.5 3 0 0 3 3 3 0 BED zinc finger Tropomyosin_1 PF12718.7 KFQ93944.1 - 0.0048 17.0 25.0 0.0048 17.0 25.0 2.8 1 1 0 2 2 2 1 Tropomyosin like PGA_cap PF09587.10 KFQ93944.1 - 0.0073 15.8 2.0 0.012 15.0 0.1 2.2 1 1 2 3 3 3 1 Bacterial capsule synthesis protein PGA_cap BRE1 PF08647.11 KFQ93944.1 - 0.0086 16.1 15.5 0.0086 16.1 15.5 4.3 1 1 4 5 5 5 1 BRE1 E3 ubiquitin ligase Baculo_PEP_C PF04513.12 KFQ93944.1 - 0.22 11.6 13.0 0.65 10.0 3.5 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus V-SNARE_C PF12352.8 KFQ93944.1 - 0.42 10.9 5.1 3.7 7.9 0.3 3.1 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Fib_alpha PF08702.10 KFQ93944.1 - 0.52 10.5 24.0 0.2 11.8 12.1 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family FUSC PF04632.12 KFQ93944.1 - 1.1 7.7 2.4 1.6 7.2 2.2 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF2316 PF10078.9 KFQ93944.1 - 1.3 9.3 19.7 2.8 8.3 3.9 4.3 1 1 3 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2316) DUF948 PF06103.11 KFQ93944.1 - 3.2 8.1 12.3 2.3 8.5 4.2 3.3 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TRAF_BIRC3_bd PF16673.5 KFQ93944.1 - 3.6 7.5 11.9 0.8 9.5 1.1 3.5 2 1 2 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain DUF3037 PF11236.8 KFQ93944.1 - 6.7 7.2 10.7 2.7 8.4 2.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) Spc7 PF08317.11 KFQ93944.1 - 7.2 5.4 40.4 0.77 8.6 27.8 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein BAR PF03114.18 KFQ93945.1 - 7.5e-75 251.7 8.3 8.8e-75 251.4 8.3 1.0 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KFQ93945.1 - 3.2e-15 55.5 0.3 1.7e-14 53.2 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFQ93945.1 - 1.2e-13 50.5 0.0 2.2e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFQ93945.1 - 1.5e-13 50.4 0.1 2.9e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.9 KFQ93945.1 - 1.5e-08 34.2 4.0 8.2e-08 31.7 2.8 2.0 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 KFQ93945.1 - 6.3e-05 22.8 5.3 0.00093 19.0 5.3 2.2 1 1 0 1 1 1 1 BAR domain of APPL family MRF_C1 PF13887.6 KFQ93945.1 - 0.027 13.6 0.2 0.18 11.0 0.1 2.2 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 DNA_pol_B_2 PF03175.13 KFQ93945.1 - 0.099 11.5 0.9 0.14 11.0 0.9 1.1 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Exonuc_VII_L PF02601.15 KFQ93945.1 - 1 8.8 4.7 1.6 8.3 4.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FH2 PF02181.23 KFQ93945.1 - 1.6 7.7 10.3 0.8 8.8 7.6 1.8 2 1 0 2 2 2 0 Formin Homology 2 Domain Sad1_UNC PF07738.13 KFQ93946.1 - 1e-35 122.6 0.0 1.1e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal TSP_1 PF00090.19 KFQ93948.1 - 9.6e-21 73.7 75.3 1.9e-05 24.8 4.4 8.0 7 2 0 7 7 7 6 Thrombospondin type 1 domain ADAM_spacer1 PF05986.14 KFQ93948.1 - 0.012 15.6 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 ADAM-TS Spacer 1 I-set PF07679.16 KFQ93949.1 - 2.8e-41 139.5 0.0 2.7e-12 46.6 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ93949.1 - 1.7e-37 127.8 0.1 4.3e-12 46.5 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFQ93949.1 - 3.1e-27 94.7 0.0 5.7e-09 36.2 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFQ93949.1 - 1.6e-19 69.9 0.0 4.4e-07 30.0 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin domain Ig_4 PF16680.5 KFQ93949.1 - 1.9e-07 31.2 0.0 0.0059 16.8 0.0 3.4 3 0 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFQ93949.1 - 2.4e-07 30.7 0.6 0.41 10.7 0.1 4.3 3 2 1 4 4 4 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFQ93949.1 - 2.6e-07 30.8 0.2 0.0026 17.9 0.0 4.7 3 3 2 5 5 5 1 Immunoglobulin V-set domain TSP_1 PF00090.19 KFQ93949.1 - 2.5e-05 24.4 11.2 2.5e-05 24.4 11.2 5.5 4 1 1 5 5 5 3 Thrombospondin type 1 domain Ig_C17orf99 PF17736.1 KFQ93949.1 - 0.0071 16.4 0.1 7.3 6.7 0.0 3.3 3 0 0 3 3 3 1 C17orf99 Ig domain V-set_CD47 PF08204.11 KFQ93949.1 - 0.076 13.0 0.2 11 6.0 0.0 3.4 3 1 0 3 3 3 0 CD47 immunoglobulin-like domain L_lactis_ph-MCP PF06673.11 KFQ93951.1 - 0.21 10.5 0.9 0.25 10.3 0.9 1.1 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein DUF3320 PF11784.8 KFQ93951.1 - 2.3 8.3 4.8 27 4.8 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3320) Perilipin PF03036.16 KFQ93952.1 - 1.5e-171 570.8 18.1 1.7e-171 570.6 18.1 1.0 1 0 0 1 1 1 1 Perilipin family SH3BP5 PF05276.14 KFQ93952.1 - 0.0016 18.3 5.3 0.0035 17.2 1.8 2.7 2 1 0 2 2 2 1 SH3 domain-binding protein 5 (SH3BP5) Syntaxin-6_N PF09177.11 KFQ93952.1 - 0.0017 18.8 6.8 0.44 11.1 1.1 3.0 1 1 1 2 2 2 2 Syntaxin 6, N-terminal HBM PF16591.5 KFQ93952.1 - 0.016 14.6 2.0 0.016 14.6 2.0 2.4 2 0 0 2 2 2 0 Helical bimodular sensor domain Snapin_Pallidin PF14712.6 KFQ93952.1 - 0.16 12.4 5.7 2.3 8.7 3.1 2.8 2 0 0 2 2 2 0 Snapin/Pallidin PXA PF02194.15 KFQ93953.1 - 9.2e-53 178.9 0.4 3.3e-51 173.9 0.3 2.9 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 KFQ93953.1 - 9e-26 90.7 1.2 1.7e-24 86.5 0.0 3.4 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.24 KFQ93953.1 - 7e-23 80.8 0.6 7e-23 80.8 0.6 2.4 2 0 0 2 2 2 1 PX domain RGS PF00615.19 KFQ93953.1 - 2.1e-21 76.4 3.4 1.8e-19 70.1 0.2 3.6 3 0 0 3 3 3 1 Regulator of G protein signaling domain Xpo1 PF08389.12 KFQ93953.1 - 0.0039 17.3 0.1 0.043 13.9 0.0 2.9 2 0 0 2 2 2 1 Exportin 1-like protein DUF1664 PF07889.12 KFQ93953.1 - 0.043 13.9 2.0 10 6.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 KFQ93953.1 - 0.096 13.0 3.6 0.25 11.7 0.4 3.2 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Thioredoxin_7 PF13899.6 KFQ93955.1 - 1.6e-25 89.1 0.4 3.6e-25 88.0 0.2 1.6 2 0 0 2 2 2 1 Thioredoxin-like Thioredox_DsbH PF03190.15 KFQ93955.1 - 3.3e-06 27.1 0.1 4.5e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.6 KFQ93955.1 - 1e-05 26.0 0.4 3.4e-05 24.2 0.4 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFQ93956.1 - 1.4e-23 82.9 0.0 3.1e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KFQ93956.1 - 0.0032 17.9 0.4 0.016 15.7 0.1 2.1 2 1 0 2 2 2 1 Thioredoxin-like domain Tetraspanin PF00335.20 KFQ93957.1 - 1.3e-15 57.7 11.4 1.7e-15 57.4 11.4 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF2981 PF11200.8 KFQ93957.1 - 0.091 12.5 1.1 0.1 12.3 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) GAPT PF11770.8 KFQ93957.1 - 3.1 7.6 6.8 0.6 10.0 1.6 2.3 1 1 1 2 2 2 0 GRB2-binding adapter (GAPT) DUF423 PF04241.15 KFQ93957.1 - 5.9 7.2 10.3 2.4 8.4 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF423) Ank_2 PF12796.7 KFQ93958.1 - 2.8e-15 56.7 0.5 8.9e-12 45.4 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFQ93958.1 - 1.3e-12 47.6 0.9 3.8e-09 36.6 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFQ93958.1 - 1.5e-12 47.7 0.5 1.7e-07 31.7 0.1 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KFQ93958.1 - 5.9e-11 42.3 0.2 6.4e-07 29.5 0.2 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFQ93958.1 - 5.6e-10 38.6 0.3 2.5e-07 30.5 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeat zf-MYND PF01753.18 KFQ93958.1 - 1.8e-09 37.5 12.7 1.8e-09 37.5 12.7 2.4 2 0 0 2 2 2 1 MYND finger DUF2151 PF10221.9 KFQ93958.1 - 0.068 11.8 6.0 0.1 11.2 6.0 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator ATP-synt_E PF05680.12 KFQ93958.1 - 0.098 13.0 6.1 0.18 12.2 6.1 1.4 1 0 0 1 1 1 0 ATP synthase E chain TraV PF09676.10 KFQ93958.1 - 0.16 12.9 5.2 0.3 12.1 5.2 1.3 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) zf-Mss51 PF13824.6 KFQ93958.1 - 0.19 11.9 5.6 0.69 10.1 5.6 1.9 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 PolC_DP2 PF03833.13 KFQ93958.1 - 0.24 9.2 6.2 0.36 8.7 6.2 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Spore_coat_CotO PF14153.6 KFQ93958.1 - 0.4 10.6 8.9 0.61 10.0 8.9 1.2 1 0 0 1 1 1 0 Spore coat protein CotO MRPL52 PF18699.1 KFQ93958.1 - 0.55 10.5 6.0 1.2 9.4 6.0 1.5 1 0 0 1 1 1 0 Mitoribosomal protein mL52 MCM_bind PF09739.9 KFQ93958.1 - 2.1 6.7 6.8 3 6.2 6.8 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor LRR_9 PF14580.6 KFQ93959.1 - 1.1e-19 70.6 3.9 1.2e-17 63.9 1.4 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 KFQ93959.1 - 3.9e-14 52.5 16.5 9.2e-06 25.9 5.6 3.3 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFQ93959.1 - 1.2e-08 34.6 13.6 4e-05 23.3 9.7 3.1 2 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 KFQ93959.1 - 0.0031 17.8 11.2 8.2 7.4 0.4 5.0 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.6 KFQ93959.1 - 1.7 8.9 10.9 2.9 8.2 0.5 3.6 4 0 0 4 4 4 0 Leucine Rich repeat Sclerostin PF05463.11 KFQ93960.1 - 7.7e-101 335.8 5.9 8.6e-101 335.7 5.9 1.0 1 0 0 1 1 1 1 Sclerostin (SOST) DAN PF03045.15 KFQ93960.1 - 1.5e-14 54.0 1.9 2.1e-14 53.5 1.9 1.3 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.22 KFQ93960.1 - 4.2e-05 23.8 7.6 0.00022 21.5 7.6 1.9 1 1 0 1 1 1 1 Cystine-knot domain ISPD_C PF18706.1 KFQ93961.1 - 3.2e-53 179.8 6.5 4.6e-53 179.3 6.5 1.2 1 0 0 1 1 1 1 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain IspD PF01128.19 KFQ93961.1 - 7.2e-29 101.1 0.0 1.5e-28 100.1 0.0 1.5 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase TPALS PF18178.1 KFQ93961.1 - 0.029 13.8 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family MIP-T3 PF10243.9 KFQ93961.1 - 0.054 13.5 0.1 5.5 7.0 0.0 2.9 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 CH-like domain Homeodomain PF00046.29 KFQ93963.1 - 1.1e-22 79.6 7.8 1.1e-22 79.6 7.8 1.8 2 0 0 2 2 2 1 Homeodomain CPSF73-100_C PF11718.8 KFQ93963.1 - 1.5 8.3 9.2 3.5 7.1 0.1 2.1 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term FA_hydroxylase PF04116.13 KFQ93964.1 - 2e-28 99.4 11.0 4.4e-28 98.3 11.0 1.6 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily DAGK_acc PF00609.19 KFQ93968.1 - 8.9e-56 188.6 0.0 2e-55 187.5 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAG_kinase_N PF14513.6 KFQ93968.1 - 1.9e-34 119.3 0.4 3.5e-25 89.1 0.0 3.0 2 1 1 3 3 3 2 Diacylglycerol kinase N-terminus DAGK_cat PF00781.24 KFQ93968.1 - 1.5e-27 95.7 0.0 2.8e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 KFQ93968.1 - 4.6e-21 74.5 34.5 1.7e-12 47.0 7.0 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_1 PF00036.32 KFQ93968.1 - 1.5e-13 49.2 0.7 4.3e-06 25.9 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFQ93968.1 - 2.8e-10 40.5 0.5 8.8e-10 38.9 0.5 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFQ93968.1 - 1.1e-09 37.4 0.4 2.7e-05 23.7 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KFQ93968.1 - 1.1e-08 34.2 0.3 0.0045 16.4 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFQ93968.1 - 9.2e-07 28.6 3.6 0.01 15.7 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFQ93968.1 - 0.00019 21.7 0.2 0.0019 18.5 0.2 2.6 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region C1_2 PF03107.16 KFQ93968.1 - 0.24 11.7 20.7 0.31 11.4 4.7 2.6 2 0 0 2 2 2 0 C1 domain ETS_PEA3_N PF04621.13 KFQ93969.1 - 6.7e-142 473.5 22.0 9.2e-142 473.0 22.0 1.2 1 0 0 1 1 1 1 PEA3 subfamily ETS-domain transcription factor N terminal domain Ets PF00178.22 KFQ93969.1 - 2.1e-38 130.6 0.2 3.6e-38 129.9 0.2 1.4 1 0 0 1 1 1 1 Ets-domain Arf PF00025.21 KFQ93971.1 - 7.6e-67 224.1 0.0 8.8e-67 223.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFQ93971.1 - 1.6e-17 63.6 0.0 1.7e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ93971.1 - 3.9e-17 62.6 0.1 5.2e-17 62.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFQ93971.1 - 2.1e-12 46.8 0.1 2.1e-12 46.8 0.1 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFQ93971.1 - 1.1e-08 34.7 0.6 1.4e-06 27.8 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KFQ93971.1 - 3.4e-08 33.6 0.1 4.7e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFQ93971.1 - 5e-05 22.8 0.0 7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFQ93971.1 - 5.3e-05 22.9 0.1 0.00026 20.6 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KFQ93971.1 - 0.0046 16.8 0.0 0.018 14.8 0.0 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein 6PF2K PF01591.18 KFQ93971.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_28 PF13521.6 KFQ93971.1 - 0.061 13.6 0.0 0.44 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KFQ93971.1 - 0.11 12.3 0.7 0.23 11.4 0.6 1.6 1 1 1 2 2 2 0 NTPase Gelsolin PF00626.22 KFQ93972.1 - 3.6e-93 305.5 0.2 2.7e-17 62.4 0.0 6.3 6 0 0 6 6 6 6 Gelsolin repeat DUF3960 PF13142.6 KFQ93972.1 - 0.17 12.1 0.0 1 9.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3960) VWD PF00094.25 KFQ93973.1 - 0.00022 21.5 0.6 0.00042 20.6 0.6 1.5 1 0 0 1 1 1 1 von Willebrand factor type D domain EGF PF00008.27 KFQ93974.1 - 3e-05 24.2 40.0 0.0012 19.1 5.5 4.4 4 0 0 4 4 4 3 EGF-like domain hEGF PF12661.7 KFQ93974.1 - 0.012 16.2 15.8 0.015 15.9 5.6 5.7 6 1 0 6 6 6 0 Human growth factor-like EGF EGF_2 PF07974.13 KFQ93975.1 - 1e-20 73.7 78.4 0.00014 22.1 10.0 5.1 5 0 0 5 5 5 5 EGF-like domain EGF PF00008.27 KFQ93975.1 - 1.3e-14 54.1 75.2 0.0056 17.0 8.1 5.8 5 0 0 5 5 5 5 EGF-like domain hEGF PF12661.7 KFQ93975.1 - 1.9e-09 37.8 84.3 0.003 18.1 5.7 7.4 8 0 0 8 8 8 5 Human growth factor-like EGF Laminin_EGF PF00053.24 KFQ93975.1 - 0.32 11.2 65.4 3 8.0 7.0 5.2 2 1 3 5 5 5 0 Laminin EGF domain EGF PF00008.27 KFQ93976.1 - 3e-14 53.0 57.9 0.00011 22.4 7.7 4.5 4 0 0 4 4 4 4 EGF-like domain EGF_2 PF07974.13 KFQ93976.1 - 1.3e-12 47.8 69.0 0.0014 19.0 13.2 4.2 4 0 0 4 4 4 4 EGF-like domain hEGF PF12661.7 KFQ93976.1 - 2.9e-08 34.1 32.5 0.00011 22.7 4.2 6.4 8 0 0 8 8 8 4 Human growth factor-like EGF Laminin_EGF PF00053.24 KFQ93976.1 - 1.9 8.7 50.9 2 8.6 11.2 4.2 1 1 3 4 4 4 0 Laminin EGF domain DUF1356 PF07092.12 KFQ93977.1 - 2.3e-117 390.3 6.3 2.7e-117 390.0 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) Anti-TRAP PF15777.5 KFQ93977.1 - 0.026 14.5 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein LEA_2 PF03168.13 KFQ93977.1 - 0.11 13.0 0.6 0.37 11.3 0.7 2.0 1 1 0 1 1 1 0 Late embryogenesis abundant protein DnaJ_CXXCXGXG PF00684.19 KFQ93977.1 - 0.22 11.9 2.8 0.21 11.9 0.6 2.1 2 1 0 2 2 2 0 DnaJ central domain TSP_1 PF00090.19 KFQ93979.1 - 4.3e-65 215.7 224.6 4.4e-13 49.2 1.9 23.9 25 1 0 25 25 25 18 Thrombospondin type 1 domain Metallophos PF00149.28 KFQ93980.1 - 7.4e-15 56.0 2.8 1.1e-14 55.4 2.8 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFQ93980.1 - 9.2e-05 22.7 0.1 0.00016 21.9 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Shisa PF13908.6 KFQ93981.1 - 1e-40 140.0 1.0 1.3e-40 139.7 1.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Chordopox_A13L PF05961.11 KFQ93981.1 - 0.078 13.2 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Acetyltransf_1 PF00583.25 KFQ93982.1 - 4.1e-12 46.3 0.1 6.5e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFQ93982.1 - 3.8e-10 39.8 0.1 1.3e-09 38.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFQ93982.1 - 2.1e-08 34.5 0.0 3.8e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFQ93982.1 - 2.5e-08 33.8 0.1 3.6e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KFQ93982.1 - 0.0025 17.9 0.1 0.0038 17.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MutS_V PF00488.21 KFQ93983.1 - 7.9e-73 244.5 0.3 1.7e-72 243.4 0.3 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFQ93983.1 - 4.2e-33 115.2 2.1 1e-31 110.7 0.7 2.4 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 KFQ93983.1 - 2.9e-19 69.7 0.2 6.9e-19 68.5 0.2 1.6 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KFQ93983.1 - 1e-15 57.8 0.1 2.6e-15 56.5 0.1 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_14 PF13173.6 KFQ93983.1 - 6.7e-06 26.2 1.5 0.00026 21.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFQ93983.1 - 0.0013 18.5 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KFQ93983.1 - 0.0095 16.4 0.2 0.076 13.5 0.1 2.5 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 KFQ93983.1 - 0.028 14.4 0.7 0.26 11.2 0.7 2.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KFQ93983.1 - 0.07 13.4 0.1 0.45 10.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain TrpBP PF02081.15 KFQ93983.1 - 0.081 12.8 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein AAA_29 PF13555.6 KFQ93983.1 - 0.1 12.3 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain CbiG_C PF01890.16 KFQ93983.1 - 0.14 12.7 0.0 0.63 10.6 0.0 2.1 2 0 0 2 2 2 0 Cobalamin synthesis G C-terminus AAA_18 PF13238.6 KFQ93983.1 - 0.15 12.6 0.0 0.45 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Prenyltrans PF00432.21 KFQ93984.1 - 3.9e-70 231.2 11.4 6.7e-15 54.5 0.2 5.9 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KFQ93984.1 - 0.00053 19.2 0.0 0.0013 17.9 0.0 1.6 1 1 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KFQ93984.1 - 0.032 13.3 0.0 3.4 6.7 0.0 3.1 2 2 2 4 4 4 0 Squalene-hopene cyclase N-terminal domain Acyl-CoA_dh_1 PF00441.24 KFQ93985.1 - 9.7e-41 139.5 2.3 1.4e-40 138.9 2.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFQ93985.1 - 8.1e-28 96.5 0.0 1.5e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KFQ93985.1 - 3.8e-27 95.2 0.1 7.3e-27 94.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KFQ93985.1 - 8.4e-20 71.4 2.9 1.3e-19 70.8 2.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KFQ93985.1 - 5.8e-05 22.9 0.0 0.0002 21.1 0.0 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Choline_transpo PF04515.12 KFQ93986.1 - 4.9e-113 377.6 34.7 4.9e-113 377.6 34.7 2.6 3 0 0 3 3 3 2 Plasma-membrane choline transporter EVC2_like PF12297.8 KFQ93986.1 - 3.6 6.2 3.9 1.3 7.7 0.1 1.9 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein UPF0242 PF06785.11 KFQ93986.1 - 8.3 6.5 5.4 21 5.1 3.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus LIM PF00412.22 KFQ93987.1 - 1.3e-24 86.2 21.8 2.8e-14 53.1 7.7 2.3 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 KFQ93987.1 - 4.1e-20 71.4 2.5 7e-20 70.6 2.5 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ93987.1 - 4.9e-05 23.1 1.3 7.6e-05 22.5 0.4 1.7 2 0 0 2 2 2 1 Homeobox KN domain DUF2175 PF09943.9 KFQ93987.1 - 0.00049 20.3 3.3 0.0016 18.7 1.0 2.4 1 1 1 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) HTH_11 PF08279.12 KFQ93987.1 - 0.21 11.6 0.0 0.41 10.6 0.0 1.4 1 0 0 1 1 1 0 HTH domain DZR PF12773.7 KFQ93987.1 - 0.77 9.8 8.6 1.7 8.7 2.2 2.7 1 1 1 2 2 2 0 Double zinc ribbon TYW3 PF02676.14 KFQ93988.1 - 2e-30 105.8 0.1 2.4e-30 105.5 0.1 1.0 1 0 0 1 1 1 1 Methyltransferase TYW3 ADH_zinc_N PF00107.26 KFQ93989.1 - 2.1e-24 86.0 0.4 9.3e-23 80.6 0.1 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFQ93989.1 - 1.8e-17 64.6 0.0 4.6e-17 63.3 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFQ93989.1 - 4e-12 46.0 0.1 2.5e-11 43.4 0.2 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KFQ93989.1 - 0.043 13.3 0.1 0.073 12.5 0.1 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus ADH_N_2 PF16884.5 KFQ93989.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Eno-Rase_NADH_b PF12242.8 KFQ93989.1 - 0.84 9.4 3.1 1 9.2 0.6 2.3 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF4590 PF15257.6 KFQ93990.1 - 5.8e-60 200.2 0.4 1e-59 199.4 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4590) Pkinase_Tyr PF07714.17 KFQ93991.1 - 1.7e-57 194.7 0.0 2.7e-57 194.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 KFQ93991.1 - 4.7e-53 177.7 22.9 5.3e-17 62.2 0.7 5.7 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ93991.1 - 5.2e-49 164.0 28.8 8e-11 42.3 0.0 8.2 3 3 6 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 KFQ93991.1 - 5.3e-47 156.3 30.9 3.1e-07 30.5 0.0 11.3 12 0 0 12 12 11 8 Ankyrin repeat Pkinase PF00069.25 KFQ93991.1 - 3.6e-46 157.7 0.0 9.1e-46 156.4 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Ank_3 PF13606.6 KFQ93991.1 - 2.8e-40 131.7 22.7 0.00036 20.7 0.0 11.6 12 0 0 12 12 12 8 Ankyrin repeat Ank_5 PF13857.6 KFQ93991.1 - 2.7e-33 113.6 12.5 3.8e-06 27.1 0.1 9.2 3 1 6 9 9 9 7 Ankyrin repeats (many copies) Kdo PF06293.14 KFQ93991.1 - 0.03 13.7 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFQ93991.1 - 0.034 13.7 1.0 0.12 12.0 0.1 2.0 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 KFQ93991.1 - 0.044 13.7 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KFQ93991.1 - 0.063 12.6 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like SPATA24 PF15175.6 KFQ93991.1 - 0.17 11.8 0.3 0.29 11.0 0.3 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 I-set PF07679.16 KFQ93992.1 - 1.8e-34 117.6 0.3 7.3e-12 45.2 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ93992.1 - 3.7e-34 117.2 0.8 1.6e-13 51.1 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFQ93992.1 - 6.2e-27 93.8 1.1 2.3e-10 40.7 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFQ93992.1 - 8.2e-24 83.6 0.7 2.9e-10 40.2 0.0 4.1 4 0 0 4 4 4 4 Immunoglobulin domain V-set PF07686.17 KFQ93992.1 - 3.2e-13 49.8 3.9 1.5e-05 25.1 0.1 5.0 3 2 1 4 4 4 3 Immunoglobulin V-set domain Izumo-Ig PF16706.5 KFQ93992.1 - 3.8e-07 30.1 0.8 0.0012 18.8 0.1 3.5 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFQ93992.1 - 1.2e-06 28.8 0.0 0.21 12.0 0.0 3.3 3 0 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFQ93992.1 - 2.8e-05 24.3 0.1 0.57 10.5 0.0 3.3 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFQ93992.1 - 0.00054 19.5 0.0 0.45 10.1 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin domain C2-set_2 PF08205.12 KFQ93992.1 - 0.001 19.1 0.1 0.79 9.8 0.0 2.7 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Adeno_E3_CR1 PF02440.15 KFQ93992.1 - 0.003 17.3 2.2 0.92 9.3 0.1 3.6 3 1 0 3 3 3 1 Adenovirus E3 region protein CR1 Ig_C17orf99 PF17736.1 KFQ93992.1 - 0.0069 16.4 0.1 0.12 12.4 0.0 2.8 3 1 0 3 3 3 1 C17orf99 Ig domain V-set_CD47 PF08204.11 KFQ93992.1 - 0.012 15.6 0.1 7.7 6.5 0.1 2.8 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain zf-RanBP PF00641.18 KFQ93993.1 - 1.8e-09 36.7 19.6 1.5e-06 27.4 9.5 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DUF35_N PF12172.8 KFQ93993.1 - 0.027 14.3 7.6 1 9.3 0.7 2.4 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.7 KFQ93993.1 - 4 7.5 8.8 8.3 6.5 2.0 2.1 1 1 1 2 2 2 0 Double zinc ribbon RecR PF02132.15 KFQ93993.1 - 4.8 6.8 7.4 0.8 9.3 1.1 2.3 2 0 0 2 2 2 0 RecR protein Cys_Met_Meta_PP PF01053.20 KFQ93994.1 - 4.4e-145 483.0 0.0 4.9e-145 482.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KFQ93994.1 - 4.2e-07 29.5 0.2 5.4e-07 29.1 0.2 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KFQ93994.1 - 3.1e-06 26.8 0.0 3.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KFQ93994.1 - 4e-06 26.0 0.1 6.3e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.16 KFQ93994.1 - 0.00047 19.1 0.0 0.00081 18.3 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage system P-protein GPCR_chapero_1 PF11904.8 KFQ93995.1 - 1.6e-69 234.7 0.5 3.2e-69 233.7 0.5 1.4 1 1 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.7 KFQ93995.1 - 1.3e-08 35.3 0.1 2.8e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFQ93995.1 - 1.7e-08 34.5 0.3 3.3e-06 27.3 0.8 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KFQ93995.1 - 1.7e-08 34.8 0.1 3.2e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ93995.1 - 6e-08 32.4 0.1 0.0013 19.1 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KFQ93995.1 - 5.7e-05 23.3 0.1 0.00011 22.4 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) LRR_8 PF13855.6 KFQ93997.1 - 1.1e-50 169.2 64.0 2.3e-12 46.5 9.7 8.5 4 1 5 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 KFQ93997.1 - 4.7e-45 150.8 74.1 4.2e-07 30.2 6.1 11.5 5 2 7 13 13 13 13 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFQ93997.1 - 2.2e-10 39.6 56.3 0.04 14.5 0.4 15.8 17 1 0 17 17 17 4 Leucine Rich Repeat LRR_9 PF14580.6 KFQ93997.1 - 1.2e-09 38.0 31.0 0.0043 16.6 2.1 5.9 2 2 4 6 6 6 6 Leucine-rich repeat DASH_Dam1 PF08653.10 KFQ93997.1 - 1.2 9.0 9.0 7.8 6.4 0.5 4.8 4 1 1 5 5 5 0 DASH complex subunit Dam1 LRR_8 PF13855.6 KFQ93998.1 - 1.9e-35 120.4 41.5 6.7e-09 35.4 0.7 6.9 2 1 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFQ93998.1 - 4.4e-29 100.1 47.8 5e-05 23.6 1.7 9.3 8 1 1 9 9 9 9 Leucine Rich repeats (2 copies) PDZ PF00595.24 KFQ93998.1 - 1.8e-16 60.3 0.0 3.5e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFQ93998.1 - 2.7e-06 27.1 0.0 5.5e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain LRR_5 PF13306.6 KFQ93998.1 - 9.9e-06 25.5 1.0 0.019 14.9 0.1 3.8 2 1 1 4 4 4 2 BspA type Leucine rich repeat region (6 copies) PDZ_2 PF13180.6 KFQ93998.1 - 4.4e-05 23.7 0.0 0.00012 22.3 0.0 1.8 1 0 0 1 1 1 1 PDZ domain LRR_1 PF00560.33 KFQ93998.1 - 0.1 13.2 39.7 6.1 7.8 0.1 11.8 11 2 0 11 11 11 0 Leucine Rich Repeat LRR_6 PF13516.6 KFQ93998.1 - 0.13 12.3 19.0 2.4 8.4 0.1 7.3 8 1 1 9 9 9 0 Leucine Rich repeat DEP PF00610.21 KFQ93999.1 - 3.5e-18 65.4 0.1 1.6e-17 63.3 0.0 2.2 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.27 KFQ93999.1 - 0.0014 18.4 10.4 0.17 11.7 0.2 4.1 5 0 0 5 5 5 2 RhoGAP domain DUF148 PF02520.17 KFQ93999.1 - 0.0066 16.6 1.1 0.019 15.0 1.1 1.8 1 0 0 1 1 1 1 Domain of unknown function DUF148 RPE65 PF03055.15 KFQ94000.1 - 4.3e-120 402.0 0.1 4.8e-120 401.9 0.1 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Carboxyl_trans PF01039.22 KFQ94001.1 - 9.8e-100 334.5 0.0 1.2e-99 334.2 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain DUF4462 PF14692.6 KFQ94002.1 - 0.067 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) MIG-14_Wnt-bd PF06664.12 KFQ94003.1 - 2.2e-94 315.9 21.8 3.3e-94 315.4 21.8 1.3 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion Ras PF00071.22 KFQ94004.1 - 5.6e-47 159.4 0.1 6.8e-47 159.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ94004.1 - 2.7e-17 63.1 0.1 5.9e-17 62.0 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ94004.1 - 3e-07 30.0 0.0 4.8e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFQ94004.1 - 3.2e-05 23.9 0.7 0.19 11.6 0.1 2.4 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFQ94004.1 - 0.00024 21.2 0.0 0.00042 20.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFQ94004.1 - 0.00056 19.4 1.3 0.003 17.0 1.3 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KFQ94004.1 - 0.0022 17.6 0.1 0.008 15.7 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KFQ94004.1 - 0.014 14.4 0.2 1.4 7.9 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KFQ94004.1 - 0.016 15.6 0.1 0.023 15.1 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KFQ94004.1 - 0.017 15.4 0.1 0.059 13.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KFQ94004.1 - 0.029 13.9 0.1 0.18 11.3 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 KFQ94004.1 - 0.036 13.8 0.6 0.11 12.1 0.0 2.1 2 1 0 3 3 3 0 AAA domain AAA_28 PF13521.6 KFQ94004.1 - 0.06 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1_Xtn PF16897.5 KFQ94004.1 - 0.082 12.9 0.1 0.18 11.8 0.0 1.6 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain G-gamma PF00631.22 KFQ94005.1 - 2.4e-13 49.9 1.2 2.5e-10 40.2 0.0 2.1 2 0 0 2 2 2 2 GGL domain Ribosomal_L7Ae PF01248.26 KFQ94006.1 - 8.9e-08 31.8 0.0 1.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family XPA_C PF05181.12 KFQ94006.1 - 0.2 11.7 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 XPA protein C-terminus HABP4_PAI-RBP1 PF04774.15 KFQ94007.1 - 2e-32 112.4 10.7 2e-32 112.4 10.7 2.0 2 0 0 2 2 2 1 Hyaluronan / mRNA binding family IHABP4_N PF16174.5 KFQ94007.1 - 6.6e-07 30.1 10.5 6.6e-07 30.1 10.5 2.5 2 1 0 2 2 2 1 Intracellular hyaluronan-binding protein 4 N-terminal TPT PF03151.16 KFQ94010.1 - 1.9e-13 50.4 7.1 2.1e-13 50.3 7.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFQ94010.1 - 6e-05 23.2 17.9 0.0086 16.2 8.2 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KFQ94010.1 - 0.0017 17.7 12.3 0.0022 17.3 12.3 1.2 1 0 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 KFQ94010.1 - 0.0019 17.2 1.1 0.0019 17.2 1.1 2.1 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like ELM2 PF01448.24 KFQ94011.1 - 1e-11 45.4 2.8 9.6e-11 42.3 0.0 3.1 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-binding PF00249.31 KFQ94011.1 - 4.2e-07 30.1 0.1 9.5e-07 28.9 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFQ94011.1 - 0.0049 16.7 0.8 0.02 14.7 0.0 2.5 2 0 0 2 2 2 1 Myb DNA-binding like Sporozoite_P67 PF05642.11 KFQ94011.1 - 4.7 5.2 11.6 13 3.8 0.0 2.2 2 0 0 2 2 2 0 Sporozoite P67 surface antigen WD40 PF00400.32 KFQ94012.1 - 1.4e-10 41.5 5.1 0.00094 20.0 0.1 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ94012.1 - 5e-06 26.7 0.0 1.3 9.3 0.0 5.0 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KFQ94012.1 - 0.0059 15.0 0.0 0.0099 14.2 0.0 1.3 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz DUF3696 PF12476.8 KFQ94012.1 - 0.16 12.4 0.0 0.49 10.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3696) HNF-1_N PF04814.13 KFQ94012.1 - 4.5 7.9 8.7 0.23 12.0 0.5 2.4 2 1 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Insulin PF00049.18 KFQ94013.1 - 0.031 15.3 0.1 0.04 14.9 0.1 1.2 1 0 0 1 1 1 0 Insulin/IGF/Relaxin family Tctex-1 PF03645.13 KFQ94014.1 - 1.8e-24 85.9 0.0 2e-24 85.8 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family muHD PF10291.9 KFQ94015.1 - 4.6e-67 226.2 0.0 6.4e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Adap_comp_sub PF00928.21 KFQ94015.1 - 1.6e-06 27.7 0.0 3.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Atg29_N PF18388.1 KFQ94015.1 - 0.061 13.2 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Atg29 N-terminal domain PDEase_I PF00233.19 KFQ94016.1 - 1.9e-93 312.6 4.8 1.9e-93 312.6 4.8 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase PDE4_UCR PF18100.1 KFQ94016.1 - 4.8e-29 101.4 7.1 9.7e-29 100.4 2.9 3.1 2 1 0 2 2 2 1 Phosphodiesterase 4 upstream conserved regions (UCR) DFP PF04127.15 KFQ94016.1 - 0.51 10.2 2.2 0.4 10.5 0.2 1.8 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein ObR_Ig PF18589.1 KFQ94019.1 - 2.2e-75 249.7 12.6 3.2e-39 133.5 3.4 3.3 3 0 0 3 3 3 2 Obesity receptor immunoglobulin like domain Lep_receptor_Ig PF06328.11 KFQ94019.1 - 1.2e-25 89.2 0.6 6.5e-25 86.9 0.6 2.4 1 0 0 1 1 1 1 Ig-like C2-type domain fn3 PF00041.21 KFQ94019.1 - 4.6e-14 52.5 7.4 0.00088 19.6 0.0 4.8 4 0 0 4 4 4 4 Fibronectin type III domain Vps55 PF04133.14 KFQ94021.1 - 4.1e-39 133.2 6.6 4.6e-39 133.0 6.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 PTEN_C2 PF10409.9 KFQ94022.1 - 3.2e-28 98.2 0.0 6.9e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DnaJ PF00226.31 KFQ94022.1 - 1.9e-06 27.9 0.0 4.4e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Y_phosphatase PF00102.27 KFQ94022.1 - 0.0085 15.7 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase ADK_lid PF05191.14 KFQ94023.1 - 1.8e-16 59.8 0.0 3.4e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid ADK PF00406.22 KFQ94023.1 - 7.9e-15 55.3 0.0 9.3e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase Pkinase_Tyr PF07714.17 KFQ94024.1 - 1.9e-139 463.3 0.0 1.2e-83 280.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFQ94024.1 - 8.3e-71 238.4 0.0 1.1e-46 159.4 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain FERM_F2 PF18377.1 KFQ94024.1 - 8.2e-57 190.8 0.9 1.7e-56 189.8 0.1 2.0 2 0 0 2 2 2 1 FERM F2 acyl-CoA binding protein-like domain Jak1_Phl PF17887.1 KFQ94024.1 - 1.5e-53 180.7 0.7 2.7e-53 179.8 0.7 1.4 1 0 0 1 1 1 1 Jak1 pleckstrin homology-like domain FERM_F1 PF18379.1 KFQ94024.1 - 1.5e-34 117.8 1.1 1.5e-34 117.8 1.1 2.0 2 0 0 2 2 2 1 FERM F1 ubiquitin-like domain SH2 PF00017.24 KFQ94024.1 - 0.00022 21.2 0.0 0.00088 19.3 0.0 2.1 1 0 0 1 1 1 1 SH2 domain Kinase-like PF14531.6 KFQ94024.1 - 0.00031 20.2 0.0 0.18 11.0 0.0 2.9 2 1 0 2 2 2 2 Kinase-like RIO1 PF01163.22 KFQ94024.1 - 0.032 13.8 0.1 0.37 10.3 0.0 2.4 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 KFQ94024.1 - 0.11 12.4 0.0 0.78 9.6 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family RRM_1 PF00076.22 KFQ94025.1 - 2.6e-26 91.2 2.8 5.2e-14 51.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFQ94025.1 - 0.0015 18.4 0.0 2.1 8.3 0.0 3.4 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KFQ94025.1 - 0.069 12.7 1.0 16 5.1 0.0 3.6 3 1 1 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 KFQ94025.1 - 0.14 12.2 0.2 10 6.2 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain VWA_N PF08399.11 KFQ94026.1 - 2.6e-22 79.6 0.1 5e-19 69.0 0.1 3.4 2 1 0 2 2 2 1 VWA N-terminal dCache_1 PF02743.18 KFQ94026.1 - 1.2e-14 54.7 3.5 5.3e-09 36.2 0.0 3.2 3 1 0 3 3 3 2 Cache domain VWA PF00092.28 KFQ94026.1 - 4.2e-07 30.4 1.8 7.7e-07 29.5 1.8 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFQ94026.1 - 1.3e-05 25.8 0.5 3.5e-05 24.4 0.5 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFQ94026.1 - 0.039 13.9 0.4 0.09 12.7 0.3 1.7 2 0 0 2 2 2 0 von Willebrand factor type A domain Pkinase_Tyr PF07714.17 KFQ94028.1 - 7e-92 307.4 0.0 9e-92 307.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ94028.1 - 1.6e-42 145.7 0.0 2.5e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kringle PF00051.18 KFQ94028.1 - 5.3e-23 81.1 4.9 1.3e-22 79.8 4.9 1.8 1 0 0 1 1 1 1 Kringle domain I-set PF07679.16 KFQ94028.1 - 1.8e-17 63.1 0.0 3e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ94028.1 - 2.9e-16 59.8 0.1 6.8e-16 58.6 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin domain Fz PF01392.22 KFQ94028.1 - 2.9e-11 44.0 3.7 2.9e-11 44.0 3.7 2.2 2 0 0 2 2 2 1 Fz domain Ig_2 PF13895.6 KFQ94028.1 - 1.6e-08 34.8 1.3 2.3e-08 34.2 0.1 1.9 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 KFQ94028.1 - 1.4e-07 31.6 0.1 3.2e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFQ94028.1 - 1.2e-05 25.4 0.4 0.00044 20.4 0.4 2.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain Haspin_kinase PF12330.8 KFQ94028.1 - 0.025 13.5 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain TMEM154 PF15102.6 KFQ94028.1 - 0.11 12.4 1.3 0.12 12.3 0.0 1.6 2 0 0 2 2 1 0 TMEM154 protein family PGM_PMM_I PF02878.16 KFQ94030.1 - 5.9e-34 116.7 0.1 9.9e-34 116.0 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KFQ94030.1 - 2e-31 108.5 0.0 3.5e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KFQ94030.1 - 8e-19 68.2 0.0 1.6e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KFQ94030.1 - 1.4e-05 25.2 0.0 3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain EF-hand_7 PF13499.6 KFQ94031.1 - 2.4e-16 59.9 1.5 5.1e-11 42.9 0.2 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KFQ94031.1 - 4.5e-14 50.9 3.2 9.5e-05 21.7 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KFQ94031.1 - 2.4e-12 46.5 5.5 4.1e-09 36.1 0.1 3.5 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KFQ94031.1 - 2e-11 42.9 3.0 1.3e-05 24.7 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 KFQ94031.1 - 1.3e-07 30.8 1.7 0.012 15.1 0.0 3.0 3 0 0 3 3 3 2 EF hand EFhand_Ca_insen PF08726.10 KFQ94031.1 - 0.025 14.7 0.0 0.06 13.4 0.0 1.7 1 0 0 1 1 1 0 Ca2+ insensitive EF hand EF-hand_4 PF12763.7 KFQ94031.1 - 0.05 13.5 0.5 3.6 7.6 0.0 3.2 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF_assoc_2 PF08356.12 KFQ94031.1 - 0.06 13.3 0.0 0.22 11.5 0.0 1.9 1 0 0 1 1 1 0 EF hand associated UPF0154 PF03672.13 KFQ94031.1 - 0.077 13.0 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) DUF3085 PF11284.8 KFQ94031.1 - 0.1 12.9 0.0 3.1 8.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3085) CENP-R PF06729.12 KFQ94032.1 - 2.2e-62 209.0 5.0 2.6e-62 208.8 5.0 1.0 1 0 0 1 1 1 1 Kinetochore component, CENP-R Peptidase_C54 PF03416.19 KFQ94033.1 - 1.6e-106 355.8 0.0 2e-106 355.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 DHR-2 PF06920.13 KFQ94034.1 - 1.9e-212 706.6 3.4 1.9e-212 706.6 3.4 1.5 2 0 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 KFQ94034.1 - 4e-53 180.1 0.2 7.7e-53 179.2 0.2 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 KFQ94034.1 - 1.4e-36 125.3 0.2 7.9e-35 119.7 0.1 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3398) DOCK_N PF16172.5 KFQ94034.1 - 0.01 14.8 1.9 0.016 14.2 0.0 2.2 3 0 0 3 3 3 0 DOCK N-terminus TEA PF01285.18 KFQ94034.1 - 0.1 12.7 0.0 0.5 10.5 0.0 2.1 2 0 0 2 2 2 0 TEA/ATTS domain UCH PF00443.29 KFQ94035.1 - 2.2e-43 148.6 0.7 1.7e-37 129.3 0.2 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFQ94035.1 - 6.6e-16 58.8 12.6 1.2e-13 51.4 12.3 3.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ank_2 PF12796.7 KFQ94037.1 - 1.3e-23 83.4 2.1 6.5e-12 45.9 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFQ94037.1 - 1.9e-22 79.0 4.3 1.3e-13 50.9 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFQ94037.1 - 5.3e-19 67.7 3.7 7.8e-05 22.9 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KFQ94037.1 - 1.3e-17 63.9 0.6 4.3e-08 33.5 0.0 4.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ94037.1 - 7.8e-17 59.7 0.5 0.00085 19.6 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat CTU2 PF10288.9 KFQ94037.1 - 0.44 10.8 3.5 1.1 9.6 3.5 1.7 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 TM2 PF05154.16 KFQ94038.1 - 4.5e-17 62.1 5.5 6.6e-17 61.6 5.5 1.2 1 0 0 1 1 1 1 TM2 domain Nitrate_red_gam PF02665.14 KFQ94038.1 - 0.027 14.0 0.1 0.03 13.9 0.1 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit CTF_NFI PF00859.18 KFQ94039.1 - 1.5e-124 415.7 27.7 1.8e-124 415.4 27.7 1.1 1 0 0 1 1 1 1 CTF/NF-I family transcription modulation region Cadherin_3 PF16184.5 KFQ94041.1 - 1.4e-10 41.2 0.0 1.4e-10 41.1 0.0 1.0 1 0 0 1 1 1 1 Cadherin-like p450 PF00067.22 KFQ94042.1 - 1.4e-09 37.3 0.4 1.4e-09 37.3 0.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFQ94043.1 - 4.2e-42 144.5 0.0 4.6e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFQ94044.1 - 3.7e-132 441.4 0.3 4.2e-132 441.2 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 HOOK PF05622.12 KFQ94045.1 - 0 1016.7 81.3 0 1016.5 81.3 1.0 1 0 0 1 1 1 1 HOOK protein ATG16 PF08614.11 KFQ94045.1 - 1.6e-05 25.3 90.8 0.2 11.9 12.6 5.5 1 1 4 5 5 5 4 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KFQ94045.1 - 4.8e-05 22.4 13.4 4.8e-05 22.4 13.4 5.0 1 1 5 6 6 6 2 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KFQ94045.1 - 0.0024 17.9 22.8 0.0024 17.9 22.8 6.1 2 2 3 6 6 6 3 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.10 KFQ94045.1 - 0.0054 16.9 5.0 0.0054 16.9 5.0 6.4 2 2 5 7 7 7 2 Fibrinogen alpha/beta chain family DUF4200 PF13863.6 KFQ94045.1 - 0.016 15.6 10.9 0.016 15.6 10.9 6.3 2 1 4 6 6 6 0 Domain of unknown function (DUF4200) Pre-PUA PF17832.1 KFQ94045.1 - 1.3 9.7 5.6 3 8.6 0.0 3.9 3 1 0 3 3 3 0 Pre-PUA-like domain GAS PF13851.6 KFQ94045.1 - 5.3 6.3 103.9 1.5 8.1 11.7 5.8 1 1 5 6 6 6 0 Growth-arrest specific micro-tubule binding HMMR_N PF15905.5 KFQ94045.1 - 8.7 5.7 96.0 4.5 6.7 22.0 4.9 1 1 3 4 4 4 0 Hyaluronan mediated motility receptor N-terminal FGGY_C PF02782.16 KFQ94046.1 - 1.7e-48 165.0 0.1 2.5e-48 164.4 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KFQ94046.1 - 2.1e-27 96.3 0.0 3e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KFQ94046.1 - 0.013 15.0 0.0 0.19 11.2 0.0 2.5 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family HSP70 PF00012.20 KFQ94046.1 - 0.14 10.3 0.0 0.19 9.9 0.0 1.1 1 0 0 1 1 1 0 Hsp70 protein Jun PF03957.13 KFQ94047.1 - 7.3e-96 320.5 9.6 1e-95 320.1 9.6 1.2 1 0 0 1 1 1 1 Jun-like transcription factor bZIP_1 PF00170.21 KFQ94047.1 - 7.8e-18 64.3 17.8 1.7e-17 63.2 17.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFQ94047.1 - 2.4e-09 37.1 14.4 6.2e-09 35.8 14.4 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFQ94047.1 - 7.6e-09 36.0 9.3 1.5e-08 35.0 9.3 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor ZapB PF06005.12 KFQ94047.1 - 0.00043 20.7 6.2 0.0018 18.7 3.6 2.4 2 0 0 2 2 2 1 Cell division protein ZapB PspA_IM30 PF04012.12 KFQ94047.1 - 0.0073 15.9 5.7 0.0073 15.9 5.7 1.4 1 1 0 1 1 1 1 PspA/IM30 family Fib_alpha PF08702.10 KFQ94047.1 - 0.01 16.0 1.0 0.017 15.3 1.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Jnk-SapK_ap_N PF09744.9 KFQ94047.1 - 0.02 15.1 7.1 0.035 14.3 7.1 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FlaC_arch PF05377.11 KFQ94047.1 - 0.023 15.1 1.6 0.054 13.9 1.6 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) TSC22 PF01166.18 KFQ94047.1 - 0.046 14.0 0.9 0.17 12.2 0.9 2.0 1 0 0 1 1 1 0 TSC-22/dip/bun family Spc29 PF17082.5 KFQ94047.1 - 0.067 13.0 3.3 0.1 12.4 1.6 2.0 2 0 0 2 2 2 0 Spindle Pole Component 29 DUF3450 PF11932.8 KFQ94047.1 - 0.1 11.9 4.5 0.15 11.3 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Seryl_tRNA_N PF02403.22 KFQ94047.1 - 0.87 9.8 7.9 1.7 8.9 7.9 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 KFQ94047.1 - 1.1 9.3 4.8 1.9 8.5 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 KFQ94047.1 - 3.9 7.3 8.8 7.2 6.4 8.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DivIC PF04977.15 KFQ94047.1 - 4 7.3 8.6 2.1 8.2 5.1 2.2 1 1 1 2 2 2 0 Septum formation initiator Ank_2 PF12796.7 KFQ94048.1 - 2.5e-90 297.2 44.6 7.5e-20 71.3 0.1 7.0 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFQ94048.1 - 3.7e-71 226.6 14.8 0.00012 22.2 0.2 14.8 15 0 0 15 15 15 14 Ankyrin repeat Ank_4 PF13637.6 KFQ94048.1 - 1.3e-70 232.9 13.4 3.2e-10 40.3 0.7 11.8 5 4 7 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.30 KFQ94048.1 - 3.2e-70 229.7 37.8 5.1e-07 29.9 0.0 14.5 14 1 1 15 15 15 14 Ankyrin repeat Ank_5 PF13857.6 KFQ94048.1 - 1.2e-68 226.2 18.4 4.1e-08 33.3 0.0 11.9 3 2 9 12 12 12 11 Ankyrin repeats (many copies) UPF0180 PF03698.13 KFQ94048.1 - 0.064 13.4 0.1 32 4.8 0.0 3.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0180) DUF2520 PF10728.9 KFQ94048.1 - 1.7 8.5 11.0 0.61 9.9 2.5 3.8 4 1 1 5 5 5 0 Domain of unknown function (DUF2520) SWIRM PF04433.17 KFQ94049.1 - 7.4e-21 74.3 0.0 2.5e-20 72.6 0.0 2.0 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 KFQ94049.1 - 3.5e-12 46.3 0.2 9.5e-12 44.9 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain JAB PF01398.21 KFQ94049.1 - 5.4e-12 45.7 0.0 1.3e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KFQ94049.1 - 7.6e-09 35.4 0.0 2e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Myb_DNA-bind_6 PF13921.6 KFQ94049.1 - 0.00016 21.9 0.7 0.00057 20.1 0.7 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain UPF0172 PF03665.13 KFQ94049.1 - 0.003 17.6 0.0 0.0072 16.4 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) Myb_DNA-bind_7 PF15963.5 KFQ94049.1 - 0.012 15.5 0.4 0.049 13.5 0.4 2.1 1 0 0 1 1 1 0 Myb DNA-binding like Peptidase_M48 PF01435.18 KFQ94050.1 - 5.7e-32 111.1 0.1 9.2e-32 110.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M48 Sulf_transp PF04143.14 KFQ94050.1 - 0.013 15.1 0.5 0.024 14.2 0.1 1.6 2 0 0 2 2 2 0 Sulphur transport Peptidase_U49 PF10463.9 KFQ94050.1 - 0.16 11.7 0.9 0.78 9.5 0.8 2.0 2 0 0 2 2 2 0 Peptidase U49 PID PF00640.23 KFQ94051.1 - 3.2e-08 33.7 0.1 5.3e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) MACPF PF01823.19 KFQ94052.1 - 2.7e-36 125.6 0.3 9.9e-36 123.8 0.1 1.9 2 0 0 2 2 2 1 MAC/Perforin domain Ldl_recept_a PF00057.18 KFQ94052.1 - 6e-09 36.0 10.9 3.1e-08 33.7 10.9 2.4 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A TSP_1 PF00090.19 KFQ94052.1 - 5.7e-08 32.8 34.6 4.6e-06 26.7 10.1 3.5 3 0 0 3 3 3 2 Thrombospondin type 1 domain MACPF PF01823.19 KFQ94053.1 - 1.1e-42 146.5 0.1 3.1e-42 145.0 0.0 1.7 2 0 0 2 2 2 1 MAC/Perforin domain Ldl_recept_a PF00057.18 KFQ94053.1 - 7.9e-11 42.0 11.5 7.9e-11 42.0 11.5 2.7 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A TSP_1 PF00090.19 KFQ94053.1 - 0.00025 21.2 32.5 0.0015 18.7 9.2 3.7 3 0 0 3 3 3 2 Thrombospondin type 1 domain DUF3655 PF12379.8 KFQ94053.1 - 0.47 10.8 8.5 1.5 9.2 2.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3655) hSH3 PF14603.6 KFQ94054.1 - 1.3e-15 57.6 0.0 2.7e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Helically-extended SH3 domain SH3_2 PF07653.17 KFQ94054.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain Pkinase PF00069.25 KFQ94055.1 - 2.9e-67 226.8 0.0 4.3e-67 226.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ94055.1 - 9.8e-37 126.6 0.0 1.7e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KFQ94055.1 - 2e-15 57.3 0.8 9e-15 55.2 0.1 2.4 3 0 0 3 3 3 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 KFQ94055.1 - 1.6e-06 27.6 0.0 2.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFQ94055.1 - 0.00053 19.6 0.3 0.0021 17.7 0.2 1.9 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KFQ94055.1 - 0.0016 17.8 0.4 0.0031 16.9 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFQ94055.1 - 0.016 15.1 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFQ94055.1 - 0.021 13.8 0.1 0.039 12.9 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain PAP2 PF01569.21 KFQ94056.1 - 7.4e-26 90.5 2.6 1.4e-25 89.7 1.6 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KFQ94056.1 - 2.2e-05 24.9 1.5 2.2e-05 24.9 1.5 1.9 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2_3 PF14378.6 KFQ94056.1 - 0.005 16.5 1.4 0.015 15.0 1.4 1.7 1 1 0 1 1 1 1 PAP2 superfamily Antimicrobial13 PF08108.11 KFQ94056.1 - 0.24 11.5 1.1 0.96 9.6 0.1 2.3 2 0 0 2 2 2 0 Halocidin family Herpes_LMP1 PF05297.11 KFQ94056.1 - 0.4 9.8 1.1 1.6 7.9 0.1 2.0 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Peptidase_S8 PF00082.22 KFQ94057.1 - 6.8e-21 74.8 1.1 1.1e-20 74.1 1.1 1.3 1 1 0 1 1 1 1 Subtilase family TMEM61 PF15105.6 KFQ94058.1 - 9.1e-47 159.3 1.2 1e-46 159.1 1.2 1.0 1 0 0 1 1 1 1 TMEM61 protein family TMEM51 PF15345.6 KFQ94058.1 - 0.029 14.2 0.0 0.036 13.9 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 CD20 PF04103.15 KFQ94058.1 - 0.03 14.4 0.7 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 CD20-like family Saf_2TM PF18303.1 KFQ94058.1 - 0.21 11.1 0.3 0.76 9.4 0.0 1.8 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain FAD_binding_4 PF01565.23 KFQ94059.1 - 8.2e-17 61.2 0.1 1.3e-16 60.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain SHIPPO-rpt PF07004.12 KFQ94060.1 - 0.056 14.4 11.7 0.29 12.1 0.4 5.1 6 0 0 6 6 6 0 Sperm-tail PG-rich repeat tRNA-synt_2b PF00587.25 KFQ94061.1 - 3.2e-26 92.4 0.0 4.7e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KFQ94061.1 - 7.9e-06 25.9 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain START PF01852.19 KFQ94062.1 - 4.3e-31 108.0 0.0 7e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 START domain 4HBT PF03061.22 KFQ94062.1 - 1.6e-21 76.4 0.1 1.6e-10 41.2 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily CRISPR_Cas2 PF09827.9 KFQ94062.1 - 0.086 13.0 0.0 0.32 11.2 0.0 1.9 2 0 0 2 2 2 0 CRISPR associated protein Cas2 SSDP PF04503.13 KFQ94063.1 - 4.7e-81 273.2 82.3 5.8e-56 190.9 57.8 2.0 1 1 1 2 2 2 2 Single-stranded DNA binding protein, SSDP PDCD9 PF07147.12 KFQ94064.1 - 3.2e-13 49.7 0.2 1.2e-09 37.9 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial 28S ribosomal protein S30 (PDCD9) Thi4 PF01946.17 KFQ94064.1 - 0.17 11.1 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_1 PF00175.21 KFQ94065.1 - 3.2e-14 53.5 0.0 1.7e-13 51.2 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KFQ94065.1 - 9.6e-13 48.3 0.0 1.5e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Oxidored-like PF09791.9 KFQ94065.1 - 5.7e-12 45.1 2.7 6e-11 41.8 3.2 2.1 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal NAD_binding_6 PF08030.12 KFQ94065.1 - 6.2e-05 23.2 0.2 0.0067 16.6 0.0 2.7 2 1 1 3 3 3 1 Ferric reductase NAD binding domain TrbC_Ftype PF09673.10 KFQ94065.1 - 0.0013 18.8 0.0 0.19 11.8 0.0 2.3 2 0 0 2 2 2 1 Type-F conjugative transfer system pilin assembly protein DUF5522 PF17653.1 KFQ94065.1 - 0.54 10.3 7.7 0.16 12.0 4.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5522) CUB PF00431.20 KFQ94066.1 - 2.1e-92 304.9 0.0 1.1e-31 109.4 0.0 3.0 3 0 0 3 3 3 3 CUB domain CUB_2 PF02408.20 KFQ94066.1 - 0.0034 17.1 0.2 0.071 12.9 0.0 2.7 3 0 0 3 3 3 1 CUB-like domain Med26 PF08711.11 KFQ94068.1 - 4e-11 42.8 0.2 4e-11 42.8 0.2 3.0 4 0 0 4 4 4 1 TFIIS helical bundle-like domain TFIIS_M PF07500.14 KFQ94068.1 - 4.7e-08 33.5 0.4 2.8e-07 31.0 0.1 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TssR PF17643.1 KFQ94068.1 - 0.078 10.9 0.0 0.087 10.7 0.0 1.0 1 0 0 1 1 1 0 Type VI secretion system, TssR BSMAP PF12280.8 KFQ94069.1 - 1.5e-70 237.3 0.5 1.5e-70 237.3 0.5 2.1 2 0 0 2 2 2 2 Brain specific membrane anchored protein Ldl_recept_a PF00057.18 KFQ94070.1 - 4.2e-11 42.9 28.5 2.3e-05 24.5 4.5 3.4 3 1 0 3 3 3 3 Low-density lipoprotein receptor domain class A LRR_6 PF13516.6 KFQ94071.1 - 2.1e-07 30.4 9.2 0.053 13.6 0.2 4.5 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.7 KFQ94071.1 - 6.6e-05 23.2 4.1 0.0074 16.7 0.1 3.5 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFQ94071.1 - 0.0075 16.0 6.1 0.015 15.0 0.5 3.0 2 1 0 2 2 2 1 Leucine rich repeat F5_F8_type_C PF00754.25 KFQ94072.1 - 0.15 12.2 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 F5/8 type C domain T4_deiodinase PF00837.17 KFQ94073.1 - 3.2e-23 82.2 0.0 3.5e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase Yip1 PF04893.17 KFQ94074.1 - 1.9e-20 73.3 12.8 2.8e-20 72.7 12.8 1.3 1 0 0 1 1 1 1 Yip1 domain Ndc1_Nup PF09531.10 KFQ94075.1 - 6.3e-127 424.8 8.0 7.7e-127 424.5 8.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup GP41 PF00517.17 KFQ94075.1 - 0.71 9.7 2.9 1.3 8.9 2.9 1.4 1 0 0 1 1 1 0 Retroviral envelope protein zf-C2H2 PF00096.26 KFQ94076.1 - 3.8e-16 58.6 29.4 0.00097 19.5 0.6 7.0 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ94076.1 - 1.8e-10 40.7 22.0 4.8e-05 23.6 0.8 5.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ94076.1 - 2.1e-07 31.2 25.9 0.005 17.6 0.2 6.6 6 0 0 6 6 6 4 C2H2-type zinc finger FOXP-CC PF16159.5 KFQ94076.1 - 2.1e-06 28.3 18.6 0.0063 17.1 0.1 5.5 1 1 4 5 5 5 3 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KFQ94076.1 - 0.0024 18.1 13.1 0.12 12.6 2.3 4.7 1 1 5 6 6 6 5 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KFQ94076.1 - 0.069 13.3 10.2 14 5.8 0.1 4.6 1 1 2 4 4 4 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 KFQ94076.1 - 0.089 13.1 6.6 14 6.1 0.2 3.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFQ94076.1 - 0.11 12.5 3.0 1.6 8.8 0.1 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 KFQ94076.1 - 0.51 10.8 7.0 3.2 8.3 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFQ94076.1 - 2 8.2 11.3 28 4.6 0.1 5.0 4 0 0 4 4 4 0 C2H2-type zinc-finger domain DM PF00751.18 KFQ94077.1 - 2.5e-20 72.1 7.6 2.5e-20 72.1 7.6 1.7 2 0 0 2 2 2 1 DM DNA binding domain Ldl_recept_a PF00057.18 KFQ94078.1 - 4e-80 263.7 143.8 5.3e-14 52.1 16.1 8.0 8 0 0 8 8 7 7 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 KFQ94078.1 - 7.7e-61 202.3 8.4 4.5e-15 55.8 0.0 5.4 5 0 0 5 5 5 5 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 KFQ94078.1 - 1.3e-16 60.6 36.9 4.8e-09 36.4 8.0 6.1 7 1 0 7 7 3 3 Coagulation Factor Xa inhibitory site SGL PF08450.12 KFQ94078.1 - 9.7e-07 28.6 0.6 0.016 14.8 0.0 2.6 1 1 2 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region EGF_CA PF07645.15 KFQ94078.1 - 3.6e-06 27.1 11.3 3.6e-06 27.1 11.3 10.3 6 2 3 9 9 5 2 Calcium-binding EGF domain cEGF PF12662.7 KFQ94078.1 - 2.2e-05 24.2 1.6 2.2e-05 24.2 1.6 5.5 4 0 0 4 4 3 2 Complement Clr-like EGF-like EGF PF00008.27 KFQ94078.1 - 5.7e-05 23.3 19.7 0.00014 22.1 4.7 9.3 9 0 0 9 9 7 2 EGF-like domain SKG6 PF08693.10 KFQ94078.1 - 0.00076 18.8 1.8 0.0017 17.7 1.8 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Arylesterase PF01731.20 KFQ94078.1 - 0.034 14.3 0.0 4.3 7.6 0.1 3.3 3 0 0 3 3 3 0 Arylesterase TMEM154 PF15102.6 KFQ94078.1 - 0.049 13.5 3.7 0.39 10.6 3.7 2.1 1 1 0 1 1 1 0 TMEM154 protein family Polyhedrin PF00738.18 KFQ94078.1 - 0.052 12.9 0.1 0.087 12.1 0.1 1.3 1 0 0 1 1 1 0 Polyhedrin NHL PF01436.21 KFQ94078.1 - 0.077 13.1 5.6 4 7.6 0.0 5.7 8 0 0 8 8 8 0 NHL repeat PAP_PilO PF06864.12 KFQ94078.1 - 0.18 10.6 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) Peptidase_M16_M PF16187.5 KFQ94079.1 - 1.1e-15 57.7 0.0 1.3e-15 57.5 0.0 1.0 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Mago_nashi PF02792.14 KFQ94080.1 - 4.3e-47 159.8 0.0 4.7e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 Mago nashi protein DUF866 PF05907.13 KFQ94081.1 - 1.3e-41 142.1 0.1 1.5e-41 141.9 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) SDF PF00375.18 KFQ94082.1 - 2.4e-125 418.6 27.9 2.8e-125 418.4 27.9 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF2417 PF10329.9 KFQ94082.1 - 0.085 12.3 0.9 0.12 11.7 0.1 1.7 2 0 0 2 2 2 0 Region of unknown function (DUF2417) LRR_8 PF13855.6 KFQ94083.1 - 1.2e-73 242.7 57.0 1.2e-15 57.0 3.2 9.9 8 4 2 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 KFQ94083.1 - 4.1e-45 151.0 67.7 1.3e-07 31.8 0.7 11.8 6 3 7 13 13 13 13 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFQ94083.1 - 3.4e-24 85.2 6.0 3.4e-07 30.3 0.1 5.2 2 1 4 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFQ94083.1 - 3.8e-20 69.3 46.0 0.31 11.7 0.4 15.5 14 3 0 14 14 14 7 Leucine Rich Repeat LRR_9 PF14580.6 KFQ94083.1 - 4.7e-16 58.8 24.7 0.0042 16.6 1.4 6.7 1 1 6 7 7 7 6 Leucine-rich repeat LRR_6 PF13516.6 KFQ94083.1 - 2.1e-11 42.9 43.2 0.71 10.1 0.5 13.3 14 0 0 14 14 14 5 Leucine Rich repeat FNIP PF05725.12 KFQ94083.1 - 0.00028 21.0 15.6 4.3 7.6 0.1 7.6 4 2 2 6 6 6 2 FNIP Repeat LRRNT PF01462.18 KFQ94083.1 - 1.2 8.9 4.5 29 4.5 0.1 3.8 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain SCP2 PF02036.17 KFQ94084.1 - 2.7e-30 104.8 1.2 5.6e-30 103.8 1.2 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family Thiolase_N PF00108.23 KFQ94084.1 - 1e-19 70.9 0.0 4e-18 65.7 0.0 2.8 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFQ94084.1 - 1.4e-11 44.1 0.6 1.6e-10 40.7 0.1 2.8 2 1 0 2 2 2 1 Thiolase, C-terminal domain Alkyl_sulf_C PF14864.6 KFQ94084.1 - 3.1e-06 27.5 0.0 5.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 KFQ94084.1 - 4.8e-05 23.7 0.0 9.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Sterol carrier protein domain ketoacyl-synt PF00109.26 KFQ94084.1 - 0.00063 19.4 0.9 0.013 15.1 0.4 2.4 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KFQ94084.1 - 0.00096 19.0 1.8 0.015 15.1 0.1 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 KFQ94084.1 - 0.0043 17.0 0.2 0.25 11.4 0.0 2.7 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.11 KFQ94084.1 - 0.0077 15.0 0.3 0.22 10.2 0.0 2.5 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) ECH_1 PF00378.20 KFQ94085.1 - 1.2e-51 175.4 0.1 1.4e-51 175.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFQ94085.1 - 2.5e-26 93.0 0.3 1.4e-25 90.5 0.3 1.8 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase LRR_4 PF12799.7 KFQ94086.1 - 4.6e-05 23.7 10.2 0.015 15.7 0.3 4.0 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) BAF250_C PF12031.8 KFQ94086.1 - 0.0025 17.1 2.7 0.0029 17.0 1.2 1.8 2 0 0 2 2 2 1 SWI/SNF-like complex subunit BAF250/Osa DNA_alkylation PF08713.11 KFQ94086.1 - 0.016 14.9 1.7 4.6 6.9 0.1 2.6 3 0 0 3 3 3 0 DNA alkylation repair enzyme DUF3361 PF11841.8 KFQ94086.1 - 0.067 13.1 12.6 0.11 12.5 0.7 4.5 3 1 0 4 4 4 0 Domain of unknown function (DUF3361) His_kinase PF06580.13 KFQ94086.1 - 0.15 12.4 1.5 0.32 11.3 0.4 2.1 2 0 0 2 2 2 0 Histidine kinase LRR_8 PF13855.6 KFQ94086.1 - 0.38 10.6 5.3 4.4 7.1 0.1 3.8 4 0 0 4 4 4 0 Leucine rich repeat Arm PF00514.23 KFQ94086.1 - 1.5 9.0 7.9 97 3.2 0.1 5.5 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Sel1 PF08238.12 KFQ94087.1 - 4.7e-15 55.7 0.1 1.5e-05 25.5 0.0 4.4 4 0 0 4 4 4 3 Sel1 repeat DUF4315 PF14193.6 KFQ94087.1 - 0.12 12.4 0.8 0.19 11.8 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) GSHPx PF00255.19 KFQ94088.1 - 4.4e-36 122.7 0.1 6.2e-36 122.3 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KFQ94088.1 - 7.9e-06 25.8 0.0 5.1e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 AhpC/TSA family TPPK_C PF12555.8 KFQ94088.1 - 0.026 14.6 0.5 0.92 9.6 0.2 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Redoxin PF08534.10 KFQ94088.1 - 0.1 12.3 0.0 0.58 9.9 0.0 2.0 1 1 0 1 1 1 0 Redoxin PAP_assoc PF03828.19 KFQ94089.1 - 1.8e-30 104.9 0.7 9.8e-16 57.7 0.2 3.0 2 0 0 2 2 2 2 Cid1 family poly A polymerase zf-CCHC PF00098.23 KFQ94089.1 - 1.1e-11 44.3 21.7 4.6e-05 23.3 1.0 4.0 3 0 0 3 3 3 3 Zinc knuckle NTP_transf_2 PF01909.23 KFQ94089.1 - 4.3e-10 39.8 0.0 1.1e-07 32.1 0.0 2.8 2 0 0 2 2 2 1 Nucleotidyltransferase domain zf-CCHC_4 PF14392.6 KFQ94089.1 - 2.5e-05 23.9 14.9 0.25 11.1 0.6 3.7 3 0 0 3 3 3 3 Zinc knuckle Polbeta PF18765.1 KFQ94089.1 - 4.7e-05 23.4 0.0 0.055 13.6 0.0 2.6 2 0 0 2 2 2 2 Polymerase beta, Nucleotidyltransferase zf-CCHC_2 PF13696.6 KFQ94089.1 - 0.003 17.3 38.8 0.055 13.3 6.7 5.4 5 0 0 5 5 5 3 Zinc knuckle Ubiq_cyt_C_chap PF03981.12 KFQ94089.1 - 0.097 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone Pex14_N PF04695.13 KFQ94089.1 - 5.7 7.6 12.3 33 5.1 12.3 2.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-CCHC_6 PF15288.6 KFQ94089.1 - 9.5 6.2 11.1 33 4.4 0.2 3.1 2 0 0 2 2 2 0 Zinc knuckle PRP38 PF03371.15 KFQ94090.1 - 1.1e-63 214.2 0.9 1.4e-63 213.9 0.9 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 KFQ94090.1 - 6.9e-06 26.6 50.9 6.9e-06 26.6 50.9 2.2 1 1 1 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF2457 PF10446.9 KFQ94090.1 - 6.6 5.8 40.2 13 4.7 40.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2457) AAA PF00004.29 KFQ94091.1 - 9e-18 65.0 0.0 1.8e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.11 KFQ94091.1 - 3.9e-16 58.8 0.2 1.1e-15 57.4 0.2 1.8 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_22 PF13401.6 KFQ94091.1 - 9.4e-12 45.4 0.0 3e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFQ94091.1 - 9.6e-12 45.6 0.0 7.6e-11 42.7 0.0 2.6 2 2 1 3 3 3 1 AAA ATPase domain AAA_lid_10 PF17872.1 KFQ94091.1 - 3.3e-10 40.0 0.3 1.4e-09 38.0 0.1 2.1 2 0 0 2 2 2 1 AAA lid domain BAH PF01426.18 KFQ94091.1 - 9.8e-10 38.3 0.2 4.2e-09 36.3 0.0 2.1 3 0 0 3 3 3 1 BAH domain AAA_19 PF13245.6 KFQ94091.1 - 0.00024 21.5 0.1 0.00063 20.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFQ94091.1 - 0.00046 20.0 0.0 0.00091 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KFQ94091.1 - 0.0017 17.8 0.0 0.014 14.8 0.0 2.1 2 0 0 2 2 2 1 Bacterial TniB protein DUF2075 PF09848.9 KFQ94091.1 - 0.0042 16.4 0.0 0.0085 15.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 KFQ94091.1 - 0.0059 16.5 0.2 0.022 14.6 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_11 PF13086.6 KFQ94091.1 - 0.18 11.6 0.0 0.18 11.6 0.0 3.0 4 0 0 4 4 4 0 AAA domain C2 PF00168.30 KFQ94092.1 - 1.6e-09 38.0 0.0 3.8e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 C2 domain HECA PF15353.6 KFQ94092.1 - 0.12 12.6 0.1 0.41 10.9 0.1 1.9 1 0 0 1 1 1 0 Headcase protein family homologue LZ_Tnp_IS66 PF13007.7 KFQ94092.1 - 0.41 11.5 0.0 0.41 11.5 0.0 3.7 4 0 0 4 4 4 0 Transposase C of IS166 homeodomain DUF3480 PF11979.8 KFQ94093.1 - 8.1e-176 584.2 0.0 1.1e-175 583.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3480) SARA PF11409.8 KFQ94093.1 - 5.9e-19 68.0 10.6 5.9e-19 68.0 10.6 2.6 3 0 0 3 3 3 1 Smad anchor for receptor activation (SARA) FYVE PF01363.21 KFQ94093.1 - 4.6e-18 65.1 15.9 4.6e-18 65.1 15.9 2.6 2 0 0 2 2 2 1 FYVE zinc finger cPLA2_C2 PF18695.1 KFQ94093.1 - 0.052 13.5 0.8 0.96 9.5 0.0 3.1 3 0 0 3 3 3 0 Cytosolic phospholipases A2 C2-domain Band_3_cyto PF07565.13 KFQ94093.1 - 0.16 11.8 0.2 0.45 10.3 0.2 1.7 1 0 0 1 1 1 0 Band 3 cytoplasmic domain NAC PF01849.18 KFQ94094.1 - 4.7e-25 87.3 0.1 8.2e-25 86.6 0.1 1.4 1 0 0 1 1 1 1 NAC domain Thioredoxin_7 PF13899.6 KFQ94095.1 - 3.5e-18 65.6 0.0 5.5e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 KFQ94095.1 - 1.7e-06 28.0 0.0 2.5e-06 27.4 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KFQ94095.1 - 0.00024 21.5 0.0 0.00039 20.8 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredox_DsbH PF03190.15 KFQ94095.1 - 0.0048 16.9 0.1 0.0056 16.7 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_9 PF14595.6 KFQ94095.1 - 0.008 16.0 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KFQ94095.1 - 0.0086 16.4 0.2 0.045 14.1 0.0 2.1 2 1 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 KFQ94095.1 - 0.016 15.1 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Glutaredoxin PF00462.24 KFQ94095.1 - 0.057 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Ras PF00071.22 KFQ94096.1 - 5.4e-61 204.9 0.5 6.5e-61 204.7 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ94096.1 - 4e-34 117.4 0.6 5.7e-34 116.9 0.6 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ94096.1 - 5.2e-13 48.8 0.2 6.3e-13 48.5 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFQ94096.1 - 4e-05 23.1 0.0 0.00015 21.2 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFQ94096.1 - 0.00022 21.3 0.0 0.0004 20.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFQ94096.1 - 0.00046 19.8 0.1 0.0015 18.1 0.1 1.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFQ94096.1 - 0.00052 19.5 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KFQ94096.1 - 0.0083 15.7 0.0 3.5 7.1 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B G-alpha PF00503.20 KFQ94096.1 - 0.016 14.4 0.3 5.6 6.0 0.0 2.8 1 1 1 2 2 2 0 G-protein alpha subunit RsgA_GTPase PF03193.16 KFQ94096.1 - 0.017 15.0 0.0 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase DUF2757 PF10955.8 KFQ94096.1 - 0.023 15.0 0.1 0.039 14.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) AAA_24 PF13479.6 KFQ94096.1 - 0.046 13.4 0.4 0.12 12.1 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFQ94096.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Peptidase_M16_M PF16187.5 KFQ94097.1 - 8.6e-86 287.7 1.7 1.6e-85 286.8 1.7 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KFQ94097.1 - 2.7e-41 141.0 0.0 2.8e-40 137.7 0.0 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFQ94097.1 - 1e-35 123.4 1.9 5e-21 75.5 0.0 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain SDA1 PF05285.12 KFQ94097.1 - 0.0055 16.2 13.4 0.0083 15.6 13.4 1.2 1 0 0 1 1 1 1 SDA1 BSP_II PF05432.11 KFQ94097.1 - 0.03 14.0 13.1 0.05 13.3 13.1 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Mpp10 PF04006.12 KFQ94097.1 - 0.13 10.7 12.7 0.26 9.7 12.7 1.4 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 KFQ94097.1 - 0.16 10.2 18.5 0.24 9.6 18.5 1.2 1 0 0 1 1 1 0 Nop14-like family EF-hand_4 PF12763.7 KFQ94098.1 - 9.2e-41 138.0 0.9 1.6e-23 82.6 0.0 3.9 4 0 0 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KFQ94098.1 - 5.3e-12 44.4 5.0 0.0021 17.4 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFQ94098.1 - 2.2e-07 30.3 1.9 0.41 10.7 0.0 4.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 KFQ94098.1 - 1.4e-06 28.7 2.0 0.46 11.0 0.0 4.7 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.6 KFQ94098.1 - 3.1e-06 26.9 3.5 0.067 13.0 0.4 3.6 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 KFQ94098.1 - 5.2e-06 25.7 3.4 0.47 10.1 0.0 3.7 3 0 0 3 3 3 2 EF hand Spc7 PF08317.11 KFQ94098.1 - 0.00024 20.1 24.0 0.00024 20.1 24.0 2.9 2 1 1 3 3 3 2 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 KFQ94098.1 - 0.0013 18.7 21.7 0.0013 18.7 21.7 4.8 3 1 2 5 5 3 2 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 KFQ94098.1 - 0.0057 16.9 16.5 0.0057 16.9 16.5 4.5 2 1 3 5 5 5 3 Autophagy protein 16 (ATG16) AAA_13 PF13166.6 KFQ94098.1 - 0.067 11.8 29.6 0.36 9.4 15.7 2.3 1 1 1 2 2 2 0 AAA domain ESSS PF10183.9 KFQ94098.1 - 0.091 13.0 0.5 0.24 11.6 0.5 1.7 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Fib_alpha PF08702.10 KFQ94098.1 - 0.1 12.8 25.3 0.096 12.9 9.5 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 KFQ94098.1 - 0.12 12.9 56.6 0.26 11.8 14.5 3.6 2 1 1 3 3 3 0 Apg6 coiled-coil region UIM PF02809.20 KFQ94098.1 - 0.19 11.7 6.1 0.48 10.5 3.5 3.0 2 0 0 2 2 2 0 Ubiquitin interaction motif RasGAP_C PF03836.15 KFQ94098.1 - 1.3 9.1 27.5 1.5 9.0 5.6 3.4 1 1 2 3 3 3 0 RasGAP C-terminus TMPIT PF07851.13 KFQ94098.1 - 1.9 7.6 28.3 0.22 10.8 14.7 2.3 1 1 1 2 2 2 0 TMPIT-like protein Laminin_II PF06009.12 KFQ94098.1 - 2.7 8.0 21.8 8.9 6.3 2.9 2.7 1 1 1 2 2 2 0 Laminin Domain II DUF3584 PF12128.8 KFQ94098.1 - 3.6 5.0 42.5 0.026 12.1 33.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) KxDL PF10241.9 KFQ94098.1 - 4.9 7.5 23.5 0.18 12.1 2.1 3.5 1 1 3 4 4 4 0 Uncharacterized conserved protein DUF1664 PF07889.12 KFQ94098.1 - 5.1 7.2 23.2 0.19 11.8 6.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Leu_zip PF15294.6 KFQ94098.1 - 8.6 5.8 35.5 0.22 11.0 26.5 2.2 1 1 1 2 2 2 0 Leucine zipper DUF3808 PF10300.9 KFQ94099.1 - 5.9e-163 543.0 5.4 5.9e-163 543.0 5.4 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_16 PF13432.6 KFQ94099.1 - 1.3e-09 38.5 3.3 0.0019 18.8 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ94099.1 - 4.1e-09 36.6 5.6 8.6e-07 29.2 1.2 3.5 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ94099.1 - 2.9e-05 24.5 4.7 0.021 15.6 0.1 4.3 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ94099.1 - 0.00066 19.5 7.1 0.0089 15.9 0.8 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ94099.1 - 0.0022 17.9 14.1 0.016 15.3 1.7 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ94099.1 - 0.0046 16.9 1.9 0.021 14.8 0.6 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFQ94099.1 - 0.0062 17.1 5.3 0.04 14.6 1.6 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ94099.1 - 0.0069 16.9 11.2 0.42 11.2 4.3 4.7 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ94099.1 - 0.0081 15.9 8.4 0.25 11.2 1.8 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFQ94099.1 - 0.0097 15.3 3.8 0.15 11.4 0.6 2.7 3 0 0 3 3 3 1 MalT-like TPR region TPR_8 PF13181.6 KFQ94099.1 - 0.02 15.1 6.3 2.5 8.6 0.5 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFQ94099.1 - 0.16 12.7 0.3 9.1 7.2 0.1 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat SOAR PF16533.5 KFQ94099.1 - 0.4 10.7 0.1 0.4 10.7 0.1 2.7 3 0 0 3 3 3 0 STIM1 Orai1-activating region zf-RING_2 PF13639.6 KFQ94100.1 - 3.5e-12 46.4 5.6 4.8e-12 46.0 5.6 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFQ94100.1 - 2.2e-11 43.3 4.6 2.2e-11 43.3 4.6 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KFQ94100.1 - 9.1e-08 32.0 2.8 1.7e-07 31.2 2.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFQ94100.1 - 4.5e-07 29.6 6.0 6.5e-07 29.1 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFQ94100.1 - 2.3e-06 27.8 7.9 1.2e-05 25.4 7.9 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KFQ94100.1 - 3e-06 27.0 2.2 4.3e-06 26.5 2.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ94100.1 - 3.6e-06 26.7 3.5 5.7e-06 26.1 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFQ94100.1 - 3e-05 23.9 1.7 4.8e-05 23.2 1.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KFQ94100.1 - 5.1e-05 22.8 2.7 8.4e-05 22.1 2.7 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KFQ94100.1 - 0.00012 21.9 2.2 0.00018 21.3 2.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFQ94100.1 - 0.062 13.5 3.7 0.11 12.6 3.7 1.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KFQ94100.1 - 0.084 12.8 1.6 0.13 12.1 1.6 1.2 1 0 0 1 1 1 0 zf-RING of BARD1-type protein BCDHK_Adom3 PF10436.9 KFQ94100.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase zf-C3H2C3 PF17122.5 KFQ94100.1 - 0.15 12.1 3.9 0.37 10.9 3.9 1.8 1 1 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 KFQ94100.1 - 0.19 11.9 8.2 4.4 7.5 8.2 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KFQ94100.1 - 0.36 10.9 6.9 4.1 7.5 7.2 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Ank_2 PF12796.7 KFQ94101.1 - 1.5e-30 105.6 3.4 2.6e-14 53.6 0.0 2.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFQ94101.1 - 5.2e-23 80.8 4.4 1.5e-10 41.1 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFQ94101.1 - 2e-18 66.5 0.3 1.7e-10 41.2 0.0 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KFQ94101.1 - 8.5e-15 54.5 2.1 0.00013 22.2 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 KFQ94101.1 - 4.1e-12 45.2 0.7 0.00042 20.5 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat DUF1843 PF08898.10 KFQ94101.1 - 0.0035 17.8 0.1 0.33 11.5 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1843) UBX PF00789.20 KFQ94102.1 - 2.4e-21 75.7 0.1 7.6e-21 74.1 0.1 1.9 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 KFQ94102.1 - 4e-05 23.3 0.8 9.6e-05 22.1 0.8 1.6 1 0 0 1 1 1 1 UBA-like domain ubiquitin PF00240.23 KFQ94102.1 - 0.00056 19.6 0.1 0.6 9.9 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin family Ubiquitin_2 PF14560.6 KFQ94102.1 - 0.098 13.1 0.1 2.6 8.5 0.0 2.8 2 0 0 2 2 2 0 Ubiquitin-like domain Borrelia_P83 PF05262.11 KFQ94102.1 - 0.3 9.5 6.1 0.43 9.0 6.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein AAA_23 PF13476.6 KFQ94102.1 - 2 8.9 7.9 3.9 7.9 7.9 1.4 1 0 0 1 1 1 0 AAA domain RRM_1 PF00076.22 KFQ94103.1 - 3.7e-66 218.9 0.1 4.1e-21 74.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFQ94103.1 - 8.4e-13 48.0 0.0 3.2e-05 23.5 0.0 3.1 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KFQ94103.1 - 3.7e-05 23.9 0.0 0.49 10.6 0.0 2.8 3 0 0 3 3 3 2 BRCA1-associated protein 2 RRM_occluded PF16842.5 KFQ94103.1 - 0.0003 20.6 0.0 1.1 9.2 0.0 3.4 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 KFQ94103.1 - 0.0026 17.8 0.0 0.43 10.7 0.0 2.5 2 0 0 2 2 2 1 RNA binding motif RRM_7 PF16367.5 KFQ94103.1 - 0.0051 16.9 0.0 1.1 9.4 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif RNA_bind PF08675.11 KFQ94103.1 - 0.06 13.4 0.0 2.7 8.1 0.0 2.7 2 1 0 2 2 2 0 RNA binding domain RRM_2 PF04059.12 KFQ94103.1 - 0.14 12.4 0.1 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif 2 Pepdidase_M14_N PF18027.1 KFQ94104.1 - 1.9e-06 28.2 0.0 2.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain SPATA6 PF14909.6 KFQ94105.1 - 2.2e-53 180.1 0.0 3.5e-53 179.5 0.0 1.3 1 0 0 1 1 1 1 Spermatogenesis-assoc protein 6 NDUFA12 PF05071.16 KFQ94106.1 - 1.6e-05 25.7 2.8 1.8e-05 25.5 2.8 1.3 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 UPF0542 PF15086.6 KFQ94107.1 - 3.3e-32 110.2 2.2 3.7e-32 110.1 2.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0542 TMEM100 PF16311.5 KFQ94107.1 - 0.12 11.9 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 100 ELO PF01151.18 KFQ94108.1 - 2.5e-67 227.0 25.4 3.1e-67 226.7 25.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family GCM PF03615.15 KFQ94109.1 - 3e-70 234.5 4.7 3e-70 234.5 4.7 1.9 2 0 0 2 2 2 1 GCM motif protein F-box-like PF12937.7 KFQ94110.1 - 9.8e-12 44.6 1.4 1.8e-11 43.7 1.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFQ94110.1 - 2.2e-08 33.7 1.6 4.1e-08 32.9 1.6 1.5 1 0 0 1 1 1 1 F-box domain MIT PF04212.18 KFQ94110.1 - 0.00044 20.3 0.8 0.00083 19.4 0.8 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Xol-1_N PF09108.10 KFQ94110.1 - 0.016 15.1 0.2 0.026 14.4 0.2 1.2 1 0 0 1 1 1 0 Switch protein XOL-1, N-terminal Pkinase PF00069.25 KFQ94111.1 - 9.6e-79 264.4 0.0 1.3e-78 264.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ94111.1 - 4.5e-37 127.7 0.1 2.1e-36 125.6 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFQ94111.1 - 0.0015 17.6 0.1 0.0015 17.6 0.1 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Anoct_dimer PF16178.5 KFQ94111.1 - 0.0044 16.8 0.6 0.01 15.5 0.6 1.5 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Dscam_C PF12355.8 KFQ94111.1 - 0.38 11.7 7.8 1.1 10.2 1.2 2.6 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal GST_C_3 PF14497.6 KFQ94112.1 - 8.2e-20 70.8 0.0 1.5e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFQ94112.1 - 1.2e-18 67.2 0.0 2.3e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFQ94112.1 - 3.5e-18 65.6 0.0 6.4e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFQ94112.1 - 0.00096 19.1 0.1 0.0024 17.9 0.0 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFQ94112.1 - 0.062 13.7 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFQ94113.1 - 8.2e-19 67.6 0.0 1.3e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFQ94113.1 - 8.2e-17 61.3 0.0 1.6e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFQ94113.1 - 2.6e-16 59.6 0.0 4.2e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFQ94113.1 - 0.0089 16.0 0.1 0.021 14.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Sa_NUDIX PF18167.1 KFQ94113.1 - 0.028 14.2 0.0 0.18 11.6 0.0 1.9 1 1 1 2 2 2 0 SMODS-associated NUDIX domain GST_N_3 PF13417.6 KFQ94113.1 - 0.046 14.1 0.0 0.13 12.7 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFQ94114.1 - 1.3e-18 67.1 0.0 2.8e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFQ94114.1 - 5.3e-17 61.8 0.2 1e-16 60.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFQ94114.1 - 3.4e-15 56.0 0.0 5.6e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFQ94114.1 - 0.0076 16.6 0.0 0.036 14.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFQ94115.1 - 2.1e-17 63.1 0.0 3.5e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFQ94115.1 - 1.5e-16 60.3 0.0 2.5e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFQ94115.1 - 8.5e-16 58.1 0.0 1.3e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFQ94115.1 - 0.012 16.0 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFQ94115.1 - 0.043 13.8 0.0 0.092 12.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tmemb_14 PF03647.13 KFQ94116.1 - 2.7e-29 101.8 8.1 3e-29 101.6 8.1 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Acyltransferase PF01553.21 KFQ94117.1 - 2.5e-19 69.3 0.0 5.1e-19 68.2 0.0 1.5 2 0 0 2 2 2 1 Acyltransferase Acyltransf_C PF16076.5 KFQ94117.1 - 2.6e-18 65.8 0.8 5.9e-18 64.7 0.8 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus zf-DNL PF05180.12 KFQ94117.1 - 0.089 12.7 0.5 18 5.4 0.1 2.6 2 0 0 2 2 2 0 DNL zinc finger PTCB-BRCT PF12738.7 KFQ94118.1 - 5.2e-21 74.4 4.8 8.4e-18 64.1 0.9 3.5 3 0 0 3 3 3 2 twin BRCT domain BRCT_2 PF16589.5 KFQ94118.1 - 6.9e-18 64.9 1.1 1.3e-08 35.1 0.1 3.6 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KFQ94118.1 - 3.7e-17 62.5 3.9 1.5e-05 25.2 0.3 3.8 3 1 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KFQ94118.1 - 0.0015 18.8 1.2 0.13 12.6 0.4 3.4 3 0 0 3 3 3 1 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 KFQ94118.1 - 0.017 15.0 0.2 1.1 9.2 0.0 3.2 3 1 0 3 3 3 0 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KFQ94118.1 - 0.02 15.0 10.0 0.43 10.7 0.4 4.5 4 0 0 4 4 4 0 BRCA1 C Terminus (BRCT) domain DUF1351 PF07083.11 KFQ94118.1 - 0.047 13.4 1.2 0.11 12.2 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) DUF1664 PF07889.12 KFQ94118.1 - 0.067 13.2 0.2 0.19 11.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fibrinogen_C PF00147.18 KFQ94119.1 - 3.2e-69 233.1 7.1 4.7e-69 232.6 7.1 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Spc29 PF17082.5 KFQ94119.1 - 0.04 13.8 13.7 0.62 9.9 2.6 2.3 1 1 1 2 2 2 0 Spindle Pole Component 29 DUF3601 PF12208.8 KFQ94119.1 - 0.14 12.3 0.3 0.7 10.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3601) MPS2 PF17060.5 KFQ94119.1 - 0.16 11.2 11.4 0.22 10.7 11.4 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 DivIC PF04977.15 KFQ94119.1 - 1.2 8.9 19.6 0.048 13.4 3.1 3.6 1 1 3 4 4 4 0 Septum formation initiator SlyX PF04102.12 KFQ94119.1 - 1.2 9.8 26.1 0.11 13.2 6.0 3.2 1 1 2 3 3 3 0 SlyX DUF724 PF05266.14 KFQ94119.1 - 3.2 7.5 14.3 2.8 7.7 11.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Phage_lysis PF03245.13 KFQ94119.1 - 4.4 7.4 12.8 0.052 13.7 4.5 2.0 2 1 0 2 2 2 0 Bacteriophage Rz lysis protein TMPIT PF07851.13 KFQ94119.1 - 5.4 6.2 18.3 0.18 11.0 9.9 2.0 1 1 1 2 2 2 0 TMPIT-like protein CENP-H PF05837.12 KFQ94119.1 - 8 6.9 22.9 0.6 10.5 4.7 2.9 1 1 2 3 3 3 0 Centromere protein H (CENP-H) WAPL PF07814.13 KFQ94121.1 - 0.054 12.3 0.0 0.057 12.2 0.0 1.0 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin CUB PF00431.20 KFQ94122.1 - 3.8e-15 56.2 0.0 5.3e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 CUB domain Sushi PF00084.20 KFQ94122.1 - 2.4e-08 34.5 0.1 3.9e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) CUB PF00431.20 KFQ94123.1 - 4.8e-284 921.7 0.0 9.4e-28 96.8 0.0 12.3 12 0 0 12 12 12 12 CUB domain Sushi PF00084.20 KFQ94123.1 - 1.9e-250 809.7 158.4 7.1e-12 45.7 0.5 27.4 27 0 0 27 27 27 27 Sushi repeat (SCR repeat) CUB_2 PF02408.20 KFQ94123.1 - 2.1e-21 75.9 11.2 0.0043 16.8 0.0 10.5 12 0 0 12 12 12 6 CUB-like domain GPCR_chapero_1 PF11904.8 KFQ94126.1 - 5.5e-32 111.4 0.0 6.6e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.7 KFQ94126.1 - 1.8e-09 38.0 0.0 3.1e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ94126.1 - 4.7e-09 36.6 0.0 8.8e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFQ94126.1 - 1.4e-08 34.8 0.0 1e-07 32.1 0.1 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ94126.1 - 7.7e-08 32.0 0.0 0.0047 17.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KFQ94126.1 - 3e-05 24.3 0.0 0.011 16.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Pkinase PF00069.25 KFQ94127.1 - 1.4e-70 237.7 0.0 2.3e-69 233.7 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ94127.1 - 3.1e-27 95.5 0.0 5e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 KFQ94127.1 - 1.7e-15 57.3 2.4 3.4e-15 56.4 2.4 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain PH PF00169.29 KFQ94127.1 - 1e-11 45.3 0.1 1.8e-11 44.4 0.1 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 KFQ94127.1 - 0.0035 16.7 0.0 0.0057 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like ATG16 PF08614.11 KFQ94127.1 - 0.056 13.7 0.3 0.15 12.3 0.3 1.7 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Pkinase_fungal PF17667.1 KFQ94127.1 - 0.066 12.0 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase HTH_WhiA PF02650.14 KFQ94127.1 - 0.07 13.5 0.7 0.18 12.2 0.3 1.9 2 0 0 2 2 2 0 WhiA C-terminal HTH domain PHD_4 PF16866.5 KFQ94128.1 - 1.8e-21 76.0 12.0 1.8e-21 76.0 12.0 2.7 2 0 0 2 2 1 1 PHD-finger zf-CXXC PF02008.20 KFQ94128.1 - 1.3e-12 47.5 21.5 1.3e-12 47.5 21.5 2.8 2 0 0 2 2 2 1 CXXC zinc finger domain JHD PF17811.1 KFQ94128.1 - 1.5e-10 41.6 0.1 3.4e-10 40.4 0.1 1.6 1 0 0 1 1 1 1 Jumonji helical domain F-box PF00646.33 KFQ94128.1 - 5.3e-09 35.7 3.9 5.3e-09 35.7 3.9 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KFQ94128.1 - 3.1e-08 33.4 6.5 6.9e-08 32.3 6.5 1.6 1 0 0 1 1 1 1 F-box-like JmjC PF02373.22 KFQ94128.1 - 3.3e-05 24.3 3.9 0.00031 21.2 0.7 3.2 2 1 0 2 2 2 1 JmjC domain, hydroxylase LRR_6 PF13516.6 KFQ94128.1 - 0.00013 21.8 6.5 4.2 7.7 0.1 6.0 6 0 0 6 6 6 2 Leucine Rich repeat Cupin_8 PF13621.6 KFQ94128.1 - 0.0071 16.1 0.1 0.12 12.0 0.1 2.3 1 1 0 1 1 1 1 Cupin-like domain FAM176 PF14851.6 KFQ94128.1 - 0.06 13.0 4.5 4 7.1 0.4 2.8 2 0 0 2 2 2 0 FAM176 family LRR_4 PF12799.7 KFQ94128.1 - 0.1 13.1 8.6 0.22 12.0 1.5 4.2 2 2 2 4 4 4 0 Leucine Rich repeats (2 copies) Cupin_1 PF00190.22 KFQ94128.1 - 0.19 11.3 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 Cupin Ras PF00071.22 KFQ94129.1 - 6.9e-52 175.3 0.0 8.5e-52 175.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ94129.1 - 1.3e-22 80.3 0.0 1.9e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ94129.1 - 5.2e-07 29.3 0.0 6.8e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family NACHT PF05729.12 KFQ94129.1 - 0.005 16.8 0.0 0.7 9.8 0.0 2.1 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.23 KFQ94129.1 - 0.018 15.1 0.0 0.028 14.5 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFQ94129.1 - 0.024 14.6 0.0 4.6 7.1 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KFQ94129.1 - 0.057 13.8 0.1 0.12 12.7 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain GTP_EFTU PF00009.27 KFQ94129.1 - 0.07 12.7 0.1 0.17 11.4 0.0 1.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain 7tm_1 PF00001.21 KFQ94130.1 - 2.3e-08 33.7 18.7 3.6e-08 33.1 18.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2070 PF09843.9 KFQ94130.1 - 2.6 6.2 13.1 2.9 6.1 13.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TssN PF17555.2 KFQ94130.1 - 5 6.4 13.7 7.2 5.9 13.7 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN 7tm_1 PF00001.21 KFQ94131.1 - 1.2e-08 34.7 19.2 1.6e-08 34.2 19.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 KFQ94132.1 - 1.8e-07 30.8 20.8 2.7e-07 30.2 20.8 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2070 PF09843.9 KFQ94132.1 - 0.99 7.6 10.8 1.3 7.3 10.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) 7tm_1 PF00001.21 KFQ94133.1 - 0.00017 21.0 17.2 0.0018 17.6 17.2 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srbc PF10316.9 KFQ94133.1 - 0.00067 19.2 1.5 0.00067 19.2 1.5 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srx PF10328.9 KFQ94133.1 - 0.0032 17.2 5.3 0.0032 17.2 5.3 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2953 PF11167.8 KFQ94133.1 - 0.029 14.4 1.0 0.23 11.6 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) SdpI PF13630.6 KFQ94133.1 - 2.1 8.6 6.2 13 6.0 6.2 2.2 1 1 0 1 1 1 0 SdpI/YhfL protein family 7tm_1 PF00001.21 KFQ94134.1 - 1.7e-05 24.3 7.5 0.00024 20.5 7.5 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srbc PF10316.9 KFQ94134.1 - 0.00032 20.3 6.7 0.0008 19.0 0.1 2.1 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srbc DUF2953 PF11167.8 KFQ94134.1 - 0.02 15.0 1.1 0.046 13.8 0.2 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2953) 7tm_1 PF00001.21 KFQ94135.1 - 2.3e-07 30.4 11.6 8.1e-07 28.6 11.6 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srbc PF10316.9 KFQ94135.1 - 0.013 15.0 7.9 0.033 13.7 5.8 2.3 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srbc RseC_MucC PF04246.12 KFQ94135.1 - 3.7 7.5 5.4 2 8.4 1.6 2.2 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC LptF_LptG PF03739.14 KFQ94135.1 - 7 5.4 10.5 10 4.8 10.5 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG 7tm_1 PF00001.21 KFQ94136.1 - 2.3e-07 30.4 11.6 8.1e-07 28.6 11.6 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srbc PF10316.9 KFQ94136.1 - 0.013 15.0 7.9 0.033 13.7 5.8 2.3 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srbc RseC_MucC PF04246.12 KFQ94136.1 - 3.7 7.5 5.4 2 8.4 1.6 2.2 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC LptF_LptG PF03739.14 KFQ94136.1 - 7 5.4 10.5 10 4.8 10.5 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG 7tm_4 PF13853.6 KFQ94137.1 - 4.9e-48 164.3 17.5 5.7e-48 164.0 17.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ94137.1 - 2.5e-29 102.4 18.3 4.1e-29 101.7 18.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFQ94138.1 - 5.7e-46 157.5 17.8 7.4e-46 157.1 17.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ94138.1 - 6.1e-25 88.0 27.4 9.9e-25 87.3 27.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFQ94138.1 - 0.00012 21.8 15.4 0.00012 21.8 15.4 2.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFQ94138.1 - 0.0018 17.7 23.9 0.0042 16.5 23.8 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFQ94139.1 - 5.1e-49 167.5 19.2 6e-49 167.3 19.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ94139.1 - 7.4e-29 100.9 18.8 1e-28 100.4 18.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFQ94139.1 - 0.0026 17.4 12.5 0.0026 17.4 12.5 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx SLC3A2_N PF16028.5 KFQ94139.1 - 0.014 14.9 0.3 0.014 14.9 0.3 1.9 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus 7tm_4 PF13853.6 KFQ94140.1 - 6.2e-44 150.8 14.6 7.4e-44 150.6 14.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ94140.1 - 1.1e-24 87.2 14.9 1.6e-24 86.7 14.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ94140.1 - 0.00017 21.1 14.1 0.0009 18.7 14.1 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx PNTB_4TM PF12769.7 KFQ94140.1 - 2 8.9 9.4 0.2 12.1 0.4 3.1 2 1 1 3 3 3 0 4TM region of pyridine nucleotide transhydrogenase, mitoch 7tm_4 PF13853.6 KFQ94141.1 - 1.9e-56 191.9 23.3 2.2e-56 191.6 23.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ94141.1 - 9.6e-27 94.0 26.0 9.6e-27 94.0 26.0 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ94141.1 - 3.5e-05 23.3 26.6 6.4e-05 22.4 26.6 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx SLC3A2_N PF16028.5 KFQ94141.1 - 0.019 14.5 0.2 0.019 14.5 0.2 2.5 3 0 0 3 3 3 0 Solute carrier family 3 member 2 N-terminus 7tm_4 PF13853.6 KFQ94142.1 - 9.6e-49 166.6 18.5 1.1e-48 166.4 18.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ94142.1 - 3.2e-19 69.3 20.5 4.1e-19 68.9 20.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ferritin PF00210.24 KFQ94143.1 - 1.6e-30 105.9 2.9 2e-30 105.6 2.9 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 KFQ94143.1 - 0.0084 16.5 1.1 0.011 16.2 1.1 1.3 1 1 0 1 1 1 1 Rubrerythrin Bestrophin PF01062.21 KFQ94144.1 - 3.7e-109 364.7 3.0 4.3e-109 364.5 3.0 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Sec2p PF06428.11 KFQ94145.1 - 9.8e-09 35.1 10.2 9.8e-09 35.1 10.2 2.2 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p IATP PF04568.12 KFQ94145.1 - 0.041 14.3 1.8 0.12 12.9 1.8 1.8 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP AviRa PF11599.8 KFQ94145.1 - 0.094 12.2 0.8 0.13 11.6 0.8 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Spc7 PF08317.11 KFQ94145.1 - 0.096 11.5 13.8 0.15 10.9 13.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 KFQ94145.1 - 0.5 10.4 12.9 0.83 9.7 12.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cob_adeno_trans PF01923.18 KFQ94145.1 - 0.68 10.0 4.1 2.1 8.4 3.9 1.9 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF4407 PF14362.6 KFQ94145.1 - 0.96 8.7 5.4 1.4 8.2 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HSP70 PF00012.20 KFQ94145.1 - 1.8 6.7 8.0 2.6 6.1 8.0 1.2 1 0 0 1 1 1 0 Hsp70 protein Uds1 PF15456.6 KFQ94145.1 - 2.2 8.4 15.2 0.99 9.6 7.3 2.5 1 1 1 2 2 2 0 Up-regulated During Septation DUF1664 PF07889.12 KFQ94145.1 - 2.3 8.2 4.3 8.3 6.5 4.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 KFQ94145.1 - 2.6 7.5 6.8 3.6 7.1 6.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2203 PF09969.9 KFQ94145.1 - 5.5 7.7 7.8 9.7 6.9 7.1 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) FA_desaturase PF00487.24 KFQ94146.1 - 2.3e-28 99.7 21.5 3.3e-16 59.9 2.3 3.1 2 1 1 3 3 3 3 Fatty acid desaturase Cyt-b5 PF00173.28 KFQ94146.1 - 1e-21 76.8 0.0 1.9e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CHDNT PF08073.12 KFQ94146.1 - 0.052 13.5 0.0 0.18 11.8 0.0 1.9 1 0 0 1 1 1 0 CHDNT (NUC034) domain FA_desaturase PF00487.24 KFQ94147.1 - 6e-33 114.7 30.8 6e-33 114.7 30.8 1.7 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 KFQ94148.1 - 1.9e-19 69.6 0.1 3.2e-19 68.9 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 KFQ94148.1 - 1.1e-12 48.4 3.0 1.1e-12 48.4 3.0 2.1 1 1 1 2 2 2 2 Fatty acid desaturase FA_desaturase PF00487.24 KFQ94149.1 - 4.2e-33 115.2 22.4 4.2e-33 115.2 22.4 1.5 1 1 1 2 2 2 1 Fatty acid desaturase Catalase PF00199.19 KFQ94150.1 - 1.4e-197 656.4 0.0 1.8e-197 656.0 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KFQ94150.1 - 4.9e-20 71.5 1.1 1.4e-19 70.1 0.3 2.1 2 0 0 2 2 2 1 Catalase-related immune-responsive BTB PF00651.31 KFQ94151.1 - 5.6e-24 84.5 0.7 1.4e-23 83.2 0.6 1.8 1 1 0 1 1 1 1 BTB/POZ domain Ank_2 PF12796.7 KFQ94151.1 - 2.3e-20 73.0 0.0 2.6e-11 44.0 0.0 3.9 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ94151.1 - 3.7e-16 59.3 0.2 0.00013 22.4 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ94151.1 - 1e-15 56.2 0.9 5.4e-05 23.3 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KFQ94151.1 - 1.9e-13 50.2 5.0 2.1e-05 24.7 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KFQ94151.1 - 4.3e-11 42.8 1.2 0.0025 18.1 0.0 5.0 4 1 1 5 5 5 3 Ankyrin repeats (many copies) BACK PF07707.15 KFQ94151.1 - 0.00086 19.4 0.1 0.0047 17.0 0.0 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch LAGLIDADG_2 PF03161.13 KFQ94151.1 - 0.11 12.6 0.5 0.31 11.1 0.4 1.8 2 0 0 2 2 2 0 LAGLIDADG DNA endonuclease family GNAT_acetyltr_2 PF13718.6 KFQ94152.1 - 2.2e-100 334.7 0.1 1.1e-99 332.4 0.0 2.2 3 0 0 3 3 3 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KFQ94152.1 - 9.2e-80 267.7 4.8 1.8e-79 266.8 4.8 1.5 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KFQ94152.1 - 2.6e-65 219.6 0.4 8e-65 218.0 0.0 2.1 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KFQ94152.1 - 5.9e-35 119.1 0.1 1.8e-34 117.6 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 KFQ94152.1 - 5.7e-05 22.9 0.0 0.21 11.3 0.0 2.6 2 1 0 2 2 2 2 AAA domain Acetyltransf_7 PF13508.7 KFQ94152.1 - 0.00058 20.2 0.0 0.0035 17.7 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_22 PF13401.6 KFQ94152.1 - 0.00082 19.7 0.2 2.3 8.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain Acetyltransf_1 PF00583.25 KFQ94152.1 - 0.0029 17.8 0.0 0.0089 16.3 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Focal_AT PF03623.13 KFQ94152.1 - 0.047 13.7 3.9 0.054 13.5 1.9 2.1 2 0 0 2 2 2 0 Focal adhesion targeting region Acetyltransf_10 PF13673.7 KFQ94152.1 - 0.066 13.1 0.1 8.6 6.3 0.0 3.4 4 0 0 4 4 4 0 Acetyltransferase (GNAT) domain Caprin-1_dimer PF18293.1 KFQ94153.1 - 3.1e-35 121.2 2.7 3.6e-35 120.9 0.2 1.9 2 0 0 2 2 2 1 Caprin-1 dimerization domain Aida_N PF08910.10 KFQ94153.1 - 0.16 12.4 2.1 0.27 11.6 2.2 1.4 1 1 0 1 1 1 0 Aida N-terminus GrpE PF01025.19 KFQ94153.1 - 0.24 11.1 5.8 0.29 10.8 5.8 1.3 1 0 0 1 1 1 0 GrpE SKIP_SNW PF02731.15 KFQ94153.1 - 3.3 7.4 7.6 5.1 6.7 7.6 1.3 1 0 0 1 1 1 0 SKIP/SNW domain LIM PF00412.22 KFQ94154.1 - 1.5e-28 98.7 20.8 1.1e-15 57.6 9.0 2.0 2 0 0 2 2 2 2 LIM domain C1_4 PF07975.12 KFQ94154.1 - 0.019 15.2 5.4 0.019 15.2 5.4 2.6 2 1 0 2 2 2 0 TFIIH C1-like domain TDH PF03347.13 KFQ94154.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Vibrio thermostable direct hemolysin DUF525 PF04379.14 KFQ94155.1 - 1.4e-29 102.1 0.1 4.7e-29 100.5 0.1 1.9 2 0 0 2 2 2 1 ApaG domain SMI1_KNR4 PF09346.10 KFQ94155.1 - 2.9e-10 40.7 0.0 7e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 KFQ94155.1 - 0.0022 18.4 0.0 0.0095 16.3 0.0 2.1 1 1 1 2 2 2 1 SMI1-KNR4 cell-wall SUKH_5 PF14567.6 KFQ94155.1 - 0.035 13.8 0.0 0.088 12.5 0.0 1.7 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall UPAR_LY6 PF00021.21 KFQ94156.1 - 0.022 15.5 13.8 0.12 13.1 13.8 2.0 1 1 0 1 1 1 0 u-PAR/Ly-6 domain Actin PF00022.19 KFQ94157.1 - 6e-150 499.4 0.0 2e-149 497.7 0.0 1.7 1 1 0 1 1 1 1 Actin Ank_2 PF12796.7 KFQ94158.1 - 1.8e-23 82.9 6.9 6.6e-10 39.4 0.2 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) SAM_1 PF00536.30 KFQ94158.1 - 4.1e-20 72.0 0.2 9.9e-20 70.8 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank_4 PF13637.6 KFQ94158.1 - 1.6e-19 70.0 3.6 6.8e-07 29.7 1.2 4.6 3 1 0 4 4 4 2 Ankyrin repeats (many copies) SAM_2 PF07647.17 KFQ94158.1 - 3.3e-18 65.6 0.2 6.9e-18 64.5 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank PF00023.30 KFQ94158.1 - 1.7e-15 56.6 7.9 0.0035 17.7 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KFQ94158.1 - 1e-13 50.1 2.1 0.67 10.7 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat SH3_2 PF07653.17 KFQ94158.1 - 5.2e-13 48.5 0.5 1.2e-12 47.3 0.5 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ank_5 PF13857.6 KFQ94158.1 - 7e-13 48.5 4.0 4.1e-06 27.0 0.0 4.5 2 2 3 5 5 5 3 Ankyrin repeats (many copies) PDZ_6 PF17820.1 KFQ94158.1 - 5.6e-10 38.9 0.2 3.2e-09 36.5 0.2 2.3 2 0 0 2 2 2 1 PDZ domain SH3_9 PF14604.6 KFQ94158.1 - 2.5e-09 36.9 0.0 5.5e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PDZ PF00595.24 KFQ94158.1 - 3.2e-08 33.8 0.0 1.3e-07 31.9 0.0 2.1 1 0 0 1 1 1 1 PDZ domain FERM_f0 PF16511.5 KFQ94158.1 - 7.4e-07 29.4 0.0 2.4e-06 27.8 0.0 1.9 2 0 0 2 2 1 1 N-terminal or F0 domain of Talin-head FERM SH3_1 PF00018.28 KFQ94158.1 - 4.2e-06 26.3 0.0 8.2e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SAM_4 PF18017.1 KFQ94158.1 - 0.048 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFQ94158.1 - 0.18 11.8 0.0 0.44 10.6 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain HS1_rep PF02218.15 KFQ94159.1 - 2.3e-110 360.6 68.2 1.1e-21 76.8 3.5 7.4 7 0 0 7 7 7 6 Repeat in HS1/Cortactin SH3_9 PF14604.6 KFQ94159.1 - 2.5e-17 62.5 0.2 5.3e-17 61.4 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFQ94159.1 - 1.6e-16 59.6 0.2 4.3e-16 58.2 0.2 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFQ94159.1 - 1.3e-09 37.6 0.0 2.9e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain TMEM210 PF15195.6 KFQ94159.1 - 1.5e-07 31.9 5.5 8.1 6.9 0.0 6.2 1 1 4 6 6 6 4 TMEM210 family AMP-binding_C_2 PF14535.6 KFQ94159.1 - 0.035 14.4 2.4 0.45 10.8 0.6 3.0 2 1 0 2 2 2 0 AMP-binding enzyme C-terminal domain Inhibitor_I48 PF10467.9 KFQ94159.1 - 0.28 11.1 1.9 1.8 8.4 0.1 2.7 2 1 1 3 3 3 0 Peptidase inhibitor clitocypin Tho2 PF11262.8 KFQ94159.1 - 0.63 9.2 7.5 1.3 8.1 7.5 1.5 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 SAM_1 PF00536.30 KFQ94160.1 - 5.3e-23 81.2 0.3 7.6e-12 45.5 0.1 3.8 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFQ94160.1 - 5e-22 77.8 0.2 4.8e-08 33.0 0.0 3.7 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) ATG16 PF08614.11 KFQ94160.1 - 0.0051 17.1 15.6 0.0051 17.1 15.6 7.5 5 2 1 6 6 6 1 Autophagy protein 16 (ATG16) HWE_HK PF07536.14 KFQ94160.1 - 0.24 12.1 28.7 0.23 12.2 2.9 6.4 3 2 3 6 6 6 0 HWE histidine kinase Death PF00531.22 KFQ94161.1 - 8.4e-20 70.7 0.3 2.4e-18 66.1 0.2 2.1 2 0 0 2 2 2 1 Death domain DED PF01335.21 KFQ94161.1 - 1.1e-19 70.5 3.0 2.3e-19 69.5 3.0 1.5 1 0 0 1 1 1 1 Death effector domain GP67 PF17634.2 KFQ94161.1 - 0.094 13.1 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Gene product 67 LprI PF07007.12 KFQ94161.1 - 0.13 12.9 0.9 1.1 9.9 0.3 2.1 1 1 1 2 2 2 0 Lysozyme inhibitor LprI Anoctamin PF04547.12 KFQ94162.1 - 1.4e-152 508.7 10.7 2e-152 508.2 10.7 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KFQ94162.1 - 1.7e-84 283.1 0.6 1.7e-84 283.1 0.6 2.4 3 0 0 3 3 3 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin FGF PF00167.18 KFQ94163.1 - 2e-36 124.8 0.1 2.3e-36 124.7 0.1 1.0 1 0 0 1 1 1 1 Fibroblast growth factor FGF PF00167.18 KFQ94164.1 - 2e-31 108.7 0.0 2.5e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Fibroblast growth factor FGF PF00167.18 KFQ94165.1 - 2.2e-19 69.8 0.0 2.7e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Yae1_N PF09811.9 KFQ94166.1 - 2.8e-11 42.9 4.9 4.5e-11 42.3 4.9 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Cyclin_N PF00134.23 KFQ94167.1 - 3.1e-38 130.4 2.4 3.1e-38 130.4 2.4 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFQ94167.1 - 1.8e-20 73.2 2.8 3.5e-20 72.3 0.4 2.3 2 1 1 3 3 3 1 Cyclin, C-terminal domain Ion_trans PF00520.31 KFQ94169.1 - 3.1e-43 147.8 50.1 4.7e-23 81.7 16.8 2.3 2 0 0 2 2 2 2 Ion transport protein CN_hydrolase PF00795.22 KFQ94170.1 - 1.9e-41 142.2 0.0 2.6e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KFQ94170.1 - 2.8e-28 98.6 0.0 6.7e-28 97.4 0.0 1.6 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 KFQ94170.1 - 0.052 13.2 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase ERG4_ERG24 PF01222.17 KFQ94171.1 - 3.2e-95 319.4 27.9 4.1e-95 319.1 27.9 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KFQ94171.1 - 0.0097 15.4 2.5 0.0097 15.4 2.5 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KFQ94171.1 - 0.031 14.7 0.1 0.031 14.7 0.1 2.3 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Orf78 PF06024.12 KFQ94171.1 - 0.037 14.3 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 Orf78 (ac78) LIM PF00412.22 KFQ94172.1 - 5.4e-29 100.2 24.3 2.3e-16 59.7 4.2 2.1 2 0 0 2 2 2 2 LIM domain zf-ACC PF17848.1 KFQ94172.1 - 0.01 15.9 8.8 0.14 12.3 0.4 3.6 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain DUF3718 PF12514.8 KFQ94172.1 - 0.046 13.9 0.6 0.091 12.9 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3718) zf_UBZ PF18439.1 KFQ94172.1 - 0.081 12.5 13.2 0.62 9.7 0.1 4.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Zn_ribbon_2 PF12674.7 KFQ94172.1 - 0.26 12.0 13.3 0.38 11.4 1.4 2.6 2 1 0 2 2 2 0 Putative zinc ribbon domain zf-TFIIB PF13453.6 KFQ94172.1 - 0.81 9.1 0.1 0.81 9.1 0.1 3.7 4 1 1 5 5 5 0 Transcription factor zinc-finger DUF2688 PF10892.8 KFQ94172.1 - 1.5 8.4 6.5 3 7.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2688) E2F_TDP PF02319.20 KFQ94173.1 - 2e-42 143.1 0.5 1.3e-20 73.2 0.0 2.7 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 KFQ94173.1 - 0.0001 22.1 0.1 0.00094 19.0 0.0 2.5 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.12 KFQ94173.1 - 0.012 15.8 1.2 14 6.0 0.0 3.5 3 0 0 3 3 3 0 B-block binding subunit of TFIIIC CH PF00307.31 KFQ94174.1 - 4.9e-14 52.4 0.1 1.3e-13 51.1 0.1 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain AAA_22 PF13401.6 KFQ94174.1 - 6e-06 26.6 0.2 0.00051 20.3 0.2 3.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFQ94174.1 - 8.2e-05 23.2 0.0 0.00043 20.8 0.0 2.4 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.6 KFQ94174.1 - 0.00038 20.5 0.0 0.001 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFQ94174.1 - 0.00042 20.7 2.3 0.0015 18.9 0.0 2.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFQ94174.1 - 0.00085 19.7 0.1 0.16 12.3 0.0 2.8 1 1 1 2 2 2 1 AAA ATPase domain CAMSAP_CH PF11971.8 KFQ94174.1 - 0.0028 17.5 0.1 0.038 13.8 0.0 2.5 2 0 0 2 2 2 1 CAMSAP CH domain PhoH PF02562.16 KFQ94174.1 - 0.0049 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein IstB_IS21 PF01695.17 KFQ94174.1 - 0.0087 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 KFQ94174.1 - 0.015 15.3 0.0 0.1 12.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 KFQ94174.1 - 0.038 13.0 0.4 0.1 11.7 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.6 KFQ94174.1 - 0.044 14.1 0.0 0.044 14.1 0.0 2.3 3 0 0 3 3 1 0 AAA domain AAA_28 PF13521.6 KFQ94174.1 - 0.045 14.0 0.0 0.099 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2205 PF10224.9 KFQ94174.1 - 0.045 13.7 3.7 0.26 11.3 2.9 2.6 2 0 0 2 2 2 0 Short coiled-coil protein AAA_24 PF13479.6 KFQ94174.1 - 0.055 13.2 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain CH_2 PF06294.11 KFQ94174.1 - 0.057 13.5 0.3 0.37 10.9 0.0 2.5 2 0 0 2 2 2 0 CH-like domain in sperm protein DUF4140 PF13600.6 KFQ94174.1 - 0.61 10.5 7.7 28 5.2 0.3 4.0 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) GIT_CC PF16559.5 KFQ94174.1 - 9.2 6.2 11.3 0.24 11.3 3.7 2.4 2 0 0 2 2 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TSNAXIP1_N PF15739.5 KFQ94174.1 - 9.3 6.7 11.9 13 6.2 4.0 3.2 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus Homeodomain PF00046.29 KFQ94175.1 - 7.6e-21 73.7 4.9 8.6e-21 73.5 3.7 1.7 2 0 0 2 2 2 1 Homeodomain DUF2986 PF11661.8 KFQ94175.1 - 0.015 15.9 1.4 0.015 15.9 1.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) Homeobox_KN PF05920.11 KFQ94175.1 - 0.016 15.1 0.1 0.033 14.1 0.1 1.5 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.8 KFQ94175.1 - 0.12 11.9 0.2 0.34 10.4 0.2 1.8 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez YdaS_antitoxin PF15943.5 KFQ94175.1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT PrmA PF06325.13 KFQ94176.1 - 2e-11 43.9 0.0 3.3e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KFQ94176.1 - 2e-10 41.2 0.3 5.7e-10 39.8 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KFQ94176.1 - 3e-09 36.3 0.1 4e-09 35.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_31 PF13847.6 KFQ94176.1 - 3.3e-09 36.7 0.1 9.6e-09 35.2 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFQ94176.1 - 2.2e-08 34.6 0.0 7e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFQ94176.1 - 4e-07 30.0 0.0 4.5e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KFQ94176.1 - 3.6e-06 26.6 0.2 1.4e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KFQ94176.1 - 0.00028 21.6 0.0 0.00076 20.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KFQ94176.1 - 0.00076 18.9 0.1 0.0014 18.1 0.1 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB FtsJ PF01728.19 KFQ94176.1 - 0.00087 19.4 0.6 0.0063 16.6 0.1 2.2 1 1 1 2 2 2 1 FtsJ-like methyltransferase Met_10 PF02475.16 KFQ94176.1 - 0.0012 18.7 0.3 0.003 17.3 0.1 1.7 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_18 PF12847.7 KFQ94176.1 - 0.0015 18.4 0.1 0.0038 17.1 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KFQ94176.1 - 0.0044 16.5 0.1 0.012 15.1 0.1 1.7 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.19 KFQ94176.1 - 0.0059 16.4 0.1 0.01 15.6 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) zf-C2H2_2 PF12756.7 KFQ94176.1 - 0.011 16.0 0.8 0.036 14.4 0.8 1.8 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) ATP-synt_B PF00430.18 KFQ94176.1 - 0.014 15.5 3.7 0.023 14.8 3.7 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Cons_hypoth95 PF03602.15 KFQ94176.1 - 0.023 14.3 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 CMAS PF02353.20 KFQ94176.1 - 0.031 13.6 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 KFQ94176.1 - 0.045 13.5 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase PRMT5_C PF17286.2 KFQ94176.1 - 0.045 13.6 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 PRMT5 oligomerisation domain PRMT5 PF05185.16 KFQ94176.1 - 0.058 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_24 PF13578.6 KFQ94176.1 - 0.083 13.9 0.0 0.6 11.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 KFQ94176.1 - 0.12 12.4 0.7 0.18 11.8 0.0 1.6 2 0 0 2 2 1 0 Methyltransferase domain DUF1707 PF08044.11 KFQ94176.1 - 0.18 11.9 1.3 0.36 10.9 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) zf-C2H2_4 PF13894.6 KFQ94176.1 - 2.1 9.4 5.6 1.1 10.3 2.0 2.5 4 0 0 4 4 1 0 C2H2-type zinc finger SNF PF00209.18 KFQ94177.1 - 1e-122 410.5 17.3 1.2e-122 410.3 17.3 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family EGF_CA PF07645.15 KFQ94178.1 - 6.6e-26 90.2 54.8 7.6e-11 42.0 5.3 11.4 11 2 2 13 13 7 4 Calcium-binding EGF domain VWC PF00093.18 KFQ94178.1 - 3.2e-20 72.2 77.8 9.9e-11 41.8 15.2 9.9 6 1 2 8 8 7 5 von Willebrand factor type C domain EGF_3 PF12947.7 KFQ94178.1 - 8.6e-12 45.0 35.5 3.2e-09 36.8 13.5 10.9 10 1 0 10 10 8 4 EGF domain cEGF PF12662.7 KFQ94178.1 - 9.9e-09 35.0 11.9 1.4e-06 28.1 2.7 11.3 11 0 0 11 11 11 5 Complement Clr-like EGF-like Laminin_G_2 PF02210.24 KFQ94178.1 - 7.6e-08 33.0 0.0 1.3e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.6 KFQ94178.1 - 8.7e-07 29.2 0.0 1.4e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily TILa PF12714.7 KFQ94178.1 - 6.3e-06 26.1 29.5 1.5e-05 24.9 10.9 11.5 6 3 5 12 12 6 4 TILa domain EGF PF00008.27 KFQ94178.1 - 6.3e-06 26.4 35.1 0.0012 19.1 3.0 11.5 12 0 0 12 12 7 4 EGF-like domain Laminin_G_1 PF00054.23 KFQ94178.1 - 0.00015 22.0 0.0 0.00039 20.6 0.0 1.7 1 1 0 1 1 1 1 Laminin G domain hEGF PF12661.7 KFQ94178.1 - 0.00052 20.5 28.7 0.0044 17.6 4.0 12.8 12 1 0 12 12 10 5 Human growth factor-like EGF EGF_2 PF07974.13 KFQ94178.1 - 0.0016 18.7 13.6 0.0016 18.7 13.6 12.4 10 3 1 11 11 8 2 EGF-like domain FXa_inhibition PF14670.6 KFQ94178.1 - 0.0096 16.2 5.9 0.0096 16.2 5.9 11.3 8 3 2 10 10 5 3 Coagulation Factor Xa inhibitory site DUF3734 PF12536.8 KFQ94178.1 - 0.21 11.9 0.0 0.43 10.9 0.0 1.4 1 0 0 1 1 1 0 Patatin phospholipase Anoctamin PF04547.12 KFQ94180.1 - 6.5e-166 552.6 22.1 8.9e-166 552.2 22.1 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KFQ94180.1 - 1.4e-77 260.5 0.5 2.1e-77 259.9 0.5 1.3 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Ctr PF04145.15 KFQ94180.1 - 0.1 13.2 5.1 0.31 11.6 0.8 3.5 4 0 0 4 4 4 0 Ctr copper transporter family MFS_1 PF07690.16 KFQ94181.1 - 5.2e-50 170.4 24.9 1.5e-48 165.6 22.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 KFQ94181.1 - 0.16 10.2 5.4 0.42 8.8 0.0 2.9 3 0 0 3 3 3 0 BT1 family FANCF PF11107.8 KFQ94183.1 - 4.9e-81 272.6 0.1 3.1e-54 184.5 0.1 2.4 2 1 0 2 2 2 2 Fanconi anemia group F protein (FANCF) GAS2 PF02187.17 KFQ94184.1 - 1.1e-27 96.0 0.1 1.8e-27 95.2 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.31 KFQ94184.1 - 3.4e-14 52.9 0.0 5e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Type2_restr_D3 PF16902.5 KFQ94185.1 - 0.061 13.2 0.5 0.19 11.7 0.1 2.1 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain CALCOCO1 PF07888.11 KFQ94185.1 - 0.15 10.9 32.8 0.24 10.2 32.8 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Leu_zip PF15294.6 KFQ94185.1 - 0.32 10.5 34.1 0.028 13.9 9.0 2.0 1 1 1 2 2 2 0 Leucine zipper CmlA_N PF18456.1 KFQ94185.1 - 0.39 10.0 9.2 0.11 11.8 1.1 2.2 1 1 1 2 2 2 0 Diiron non-heme beta-hydroxylase N-terminal domain DUF3584 PF12128.8 KFQ94185.1 - 0.7 7.3 27.3 0.98 6.9 27.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1612 PF07756.12 KFQ94185.1 - 0.72 10.1 7.4 13 6.1 2.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1612) EzrA PF06160.12 KFQ94185.1 - 0.79 7.8 27.2 0.05 11.8 3.7 3.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA YkyA PF10368.9 KFQ94185.1 - 0.8 9.4 34.7 0.077 12.7 21.1 2.3 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein WEMBL PF05701.11 KFQ94185.1 - 1 8.0 30.2 74 1.8 30.7 2.0 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Filament PF00038.21 KFQ94185.1 - 1.7 8.2 31.3 7.5 6.0 4.4 2.9 1 1 2 3 3 3 0 Intermediate filament protein MAD PF05557.13 KFQ94185.1 - 2 6.7 33.1 2.3 6.5 33.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Cep57_CLD_2 PF14197.6 KFQ94185.1 - 2.3 8.3 32.1 4.8 7.3 7.7 3.8 1 1 3 4 4 4 0 Centrosome localisation domain of PPC89 TPR_MLP1_2 PF07926.12 KFQ94185.1 - 4.8 7.2 38.2 0.13 12.3 21.7 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KFQ94185.1 - 5.6 5.7 35.1 2 7.2 25.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 KFQ94185.1 - 6.1 4.6 20.1 0.49 8.3 14.8 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DHR10 PF18595.1 KFQ94185.1 - 6.1 6.9 38.3 1.3 9.1 21.2 3.0 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain YfcL PF08891.11 KFQ94185.1 - 6.7 7.1 9.0 15 6.0 1.9 2.9 2 1 0 2 2 2 0 YfcL protein TMEM192 PF14802.6 KFQ94185.1 - 7.3 5.6 9.3 53 2.8 9.3 2.0 1 1 0 1 1 1 0 TMEM192 family YabA PF06156.13 KFQ94185.1 - 8.6 7.1 27.0 9.2 7.0 5.5 3.1 1 1 1 2 2 2 0 Initiation control protein YabA Fib_alpha PF08702.10 KFQ94185.1 - 8.8 6.5 23.6 4.9 7.3 16.7 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4047 PF13256.6 KFQ94185.1 - 9.1 6.5 14.5 3.6 7.8 0.9 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4047) Anoctamin PF04547.12 KFQ94186.1 - 1.6e-161 538.2 15.0 2e-161 537.8 15.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KFQ94186.1 - 2.1e-76 256.6 1.8 3.7e-76 255.8 1.8 1.4 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin SSF PF00474.17 KFQ94187.1 - 3.4e-39 134.9 20.8 4.3e-39 134.5 20.8 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family NdhL PF10716.9 KFQ94187.1 - 0.28 11.2 7.3 0.091 12.7 2.4 2.7 3 0 0 3 3 3 0 NADH dehydrogenase transmembrane subunit TauD PF02668.16 KFQ94188.1 - 1.1e-39 136.9 0.0 1.5e-39 136.4 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KFQ94188.1 - 1.1e-21 77.2 3.2 4.8e-17 62.4 0.5 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF971) CsiD PF08943.10 KFQ94188.1 - 0.00028 20.1 0.0 0.00048 19.3 0.0 1.2 1 0 0 1 1 1 1 CsiD DSBA PF01323.20 KFQ94188.1 - 0.011 15.5 0.1 0.025 14.4 0.1 1.6 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Raf1_N PF18578.1 KFQ94188.1 - 0.07 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Rubisco accumulation factor 1 alpha helical domain DUF4207 PF13904.6 KFQ94189.1 - 1.2e-30 107.1 36.7 1.4e-30 106.8 36.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) Ndc1_Nup PF09531.10 KFQ94189.1 - 2.6 6.6 7.4 2.7 6.6 7.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Borrelia_P83 PF05262.11 KFQ94189.1 - 3.6 6.0 30.8 4.4 5.7 30.8 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein LRR_8 PF13855.6 KFQ94190.1 - 6.4e-68 224.4 32.7 3.9e-17 61.7 3.7 7.7 3 2 4 7 7 7 7 Leucine rich repeat LRR_5 PF13306.6 KFQ94190.1 - 6.8e-45 152.1 0.0 7.4e-13 48.6 0.0 4.1 1 1 4 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFQ94190.1 - 4.2e-36 122.3 40.5 6.4e-08 32.8 0.1 9.3 4 2 6 11 11 11 10 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFQ94190.1 - 4.8e-17 62.0 8.3 4.4e-06 26.3 0.2 3.8 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 KFQ94190.1 - 2.3e-12 45.6 28.3 2.4 9.1 0.0 12.7 13 1 0 13 13 13 4 Leucine Rich Repeat 7tm_1 PF00001.21 KFQ94190.1 - 8e-12 45.0 11.8 1.3e-11 44.4 11.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Sigma70_r4 PF04545.16 KFQ94190.1 - 0.16 11.5 0.0 0.41 10.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 LRR_6 PF13516.6 KFQ94190.1 - 0.46 10.7 38.2 1.7 8.9 0.1 9.7 11 0 0 11 11 11 0 Leucine Rich repeat L27 PF02828.16 KFQ94191.1 - 5.5e-23 80.5 0.3 1.3e-22 79.3 0.2 1.7 2 0 0 2 2 2 1 L27 domain PDZ PF00595.24 KFQ94191.1 - 4.7e-21 74.9 0.6 6.9e-21 74.4 0.6 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFQ94191.1 - 1.3e-13 50.6 0.6 2.6e-13 49.6 0.2 1.7 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KFQ94191.1 - 0.0044 17.3 0.0 0.0073 16.6 0.0 1.3 1 0 0 1 1 1 1 PDZ domain His_Phos_2 PF00328.22 KFQ94191.1 - 0.084 12.2 0.0 0.091 12.1 0.0 1.3 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) NGF PF00243.18 KFQ94192.1 - 1.7e-46 157.1 2.4 2.2e-46 156.7 2.4 1.2 1 0 0 1 1 1 1 Nerve growth factor family Spaetzle PF16077.5 KFQ94192.1 - 7.6e-05 23.2 0.9 0.00011 22.7 0.9 1.2 1 0 0 1 1 1 1 Spaetzle Kinesin PF00225.23 KFQ94193.1 - 5.4e-115 383.9 0.9 5.4e-115 383.9 0.9 2.5 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KFQ94193.1 - 3.1e-24 85.6 0.1 1.1e-23 83.8 0.1 2.0 1 0 0 1 1 1 1 Microtubule binding DUF2443 PF10398.9 KFQ94193.1 - 2 8.5 4.9 1.5 8.9 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2443) Methyltransf_5 PF01795.19 KFQ94194.1 - 3.8e-81 273.0 0.1 1.8e-80 270.8 0.1 1.8 1 1 0 1 1 1 1 MraW methylase family Methyltr_RsmB-F PF01189.17 KFQ94194.1 - 0.00014 21.6 0.0 0.00051 19.7 0.0 1.8 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 KFQ94194.1 - 0.00077 19.3 0.0 0.43 10.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KFQ94194.1 - 0.0075 16.9 0.0 0.061 14.0 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFQ94194.1 - 0.017 15.8 0.0 0.95 10.2 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_15 PF09445.10 KFQ94194.1 - 0.042 13.4 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_12 PF08242.12 KFQ94194.1 - 0.088 13.6 0.1 2.6 8.8 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase domain MTS PF05175.14 KFQ94194.1 - 0.14 11.7 0.0 4.3 6.9 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.18 KFQ94194.1 - 0.16 11.3 0.0 1.8 7.9 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Cys_knot PF00007.22 KFQ94195.1 - 6.4e-31 106.8 17.5 8.2e-31 106.4 17.5 1.1 1 0 0 1 1 1 1 Cystine-knot domain ARF7EP_C PF14949.6 KFQ94196.1 - 2.1e-36 124.7 6.4 2.2e-36 124.6 5.2 1.7 2 0 0 2 2 2 1 ARF7 effector protein C-terminus Transposon_TraM PF12508.8 KFQ94196.1 - 0.094 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Conjugative transposon, TraM Metallophos PF00149.28 KFQ94197.1 - 2e-11 44.8 0.8 3e-11 44.2 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFQ94197.1 - 0.00042 20.6 0.0 0.17 12.1 0.0 2.3 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain DnaJ PF00226.31 KFQ94199.1 - 6.4e-17 61.4 0.2 8.9e-17 61.0 0.2 1.2 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 KFQ94199.1 - 2.2e-12 46.5 6.3 3.8e-12 45.7 6.3 1.4 1 0 0 1 1 1 1 CSL zinc finger Peptidase_S24 PF00717.23 KFQ94200.1 - 1e-12 47.8 0.0 1.8e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KFQ94200.1 - 2.5e-07 30.6 0.0 0.00065 19.5 0.0 2.8 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 PAXNEB PF05625.11 KFQ94201.1 - 2.3e-91 306.7 0.0 2.4e-91 306.6 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein PAX PF00292.18 KFQ94202.1 - 1e-39 135.3 0.1 2.1e-39 134.3 0.1 1.4 1 0 0 1 1 1 1 'Paired box' domain Homeodomain PF00046.29 KFQ94202.1 - 6.3e-23 80.4 4.5 1.1e-22 79.6 4.5 1.4 1 0 0 1 1 1 1 Homeodomain HTH_32 PF13565.6 KFQ94202.1 - 0.017 15.7 1.7 0.084 13.5 0.0 2.4 2 1 0 2 2 2 0 Homeodomain-like domain Homeobox_KN PF05920.11 KFQ94202.1 - 0.13 12.2 1.1 0.21 11.5 0.1 1.8 2 0 0 2 2 2 0 Homeobox KN domain EF-hand_1 PF00036.32 KFQ94203.1 - 1.1e-17 62.1 17.2 0.001 18.5 0.1 6.8 6 1 0 6 6 6 5 EF hand EF-hand_6 PF13405.6 KFQ94203.1 - 1.3e-16 59.0 13.2 0.00098 18.9 0.0 6.4 6 0 0 6 6 6 5 EF-hand domain EF-hand_7 PF13499.6 KFQ94203.1 - 9.1e-16 58.1 15.6 2.8e-07 30.9 0.3 4.3 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KFQ94203.1 - 1.2e-09 37.2 23.8 0.011 15.2 0.2 6.7 6 1 0 6 6 6 4 EF hand EF-hand_8 PF13833.6 KFQ94203.1 - 8.5e-06 25.5 16.0 0.21 11.5 0.3 6.1 6 2 2 8 8 8 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFQ94203.1 - 0.0011 19.3 10.8 0.22 11.8 0.1 3.5 3 1 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Homez PF11569.8 KFQ94203.1 - 0.36 10.3 2.7 4.9 6.7 0.2 3.0 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez EF-hand_4 PF12763.7 KFQ94203.1 - 4.9 7.2 12.6 2.7 8.0 0.2 4.3 4 1 1 5 5 5 0 Cytoskeletal-regulatory complex EF hand WT1 PF02165.15 KFQ94204.1 - 9.5e-102 340.2 9.6 8.3e-101 337.1 9.6 2.2 1 1 0 1 1 1 1 Wilm's tumour protein zf-H2C2_2 PF13465.6 KFQ94204.1 - 2.2e-15 56.3 35.4 6.6e-07 29.5 2.9 5.6 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ94204.1 - 3.2e-13 49.3 43.9 1.8e-05 24.9 3.1 5.2 5 0 0 5 5 5 4 Zinc finger, C2H2 type FOXP-CC PF16159.5 KFQ94204.1 - 0.0003 21.3 11.8 0.0054 17.3 0.5 3.9 2 1 2 4 4 4 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KFQ94204.1 - 0.0013 19.4 45.2 0.0058 17.4 1.8 5.4 6 0 0 6 6 4 3 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KFQ94204.1 - 0.0035 17.5 6.5 0.65 10.1 0.0 3.2 2 1 0 3 3 3 2 Aberrant zinc-finger zf-C2H2_8 PF15909.5 KFQ94204.1 - 0.0079 16.5 12.6 0.054 13.8 2.9 2.9 1 1 2 3 3 3 2 C2H2-type zinc ribbon zf-met PF12874.7 KFQ94204.1 - 0.046 14.1 2.0 0.046 14.1 2.0 4.6 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFQ94204.1 - 0.38 11.1 16.0 0.13 12.6 1.5 4.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Ofd1_CTDD PF10637.9 KFQ94204.1 - 1.7 7.9 3.5 2 7.7 0.9 1.9 1 1 1 2 2 2 0 Oxoglutarate and iron-dependent oxygenase degradation C-term CCAP PF11105.8 KFQ94204.1 - 4.3 7.3 5.6 0.38 10.7 0.4 1.9 2 0 0 2 2 2 0 Arthropod cardioacceleratory peptide 2a PCI PF01399.27 KFQ94205.1 - 7e-15 55.4 1.7 4.6e-14 52.8 1.0 2.4 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 KFQ94205.1 - 3.5e-12 45.8 2.9 6.7e-12 44.9 2.9 1.5 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix CCDC73 PF15818.5 KFQ94206.1 - 0 1241.7 87.3 0 1241.5 87.3 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 73 family Gla PF00594.20 KFQ94207.1 - 6.2e-19 67.9 7.4 6.2e-19 67.9 7.4 1.6 2 0 0 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain WBP-1 PF11669.8 KFQ94207.1 - 8.2e-05 23.2 0.0 0.00018 22.1 0.0 1.5 1 0 0 1 1 1 1 WW domain-binding protein 1 Orthoreo_P10 PF07204.11 KFQ94207.1 - 0.0029 17.5 0.7 0.0029 17.5 0.7 1.6 2 0 0 2 2 2 1 Orthoreovirus membrane fusion protein p10 EphA2_TM PF14575.6 KFQ94207.1 - 0.0074 17.1 0.0 0.019 15.8 0.0 1.8 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.12 KFQ94207.1 - 0.011 15.3 0.2 0.017 14.7 0.2 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family TMEM154 PF15102.6 KFQ94207.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Adeno_E3_CR2 PF02439.15 KFQ94207.1 - 0.03 14.1 3.7 0.059 13.1 3.7 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Prominin PF05478.11 KFQ94207.1 - 0.15 10.0 0.0 0.17 9.8 0.0 1.0 1 0 0 1 1 1 0 Prominin Comm PF15957.5 KFQ94207.1 - 4.1 7.8 4.7 33 4.9 4.7 2.1 1 1 0 1 1 1 0 Commissureless DUF4211 PF13926.6 KFQ94208.1 - 1.3e-21 77.2 1.2 3.6e-21 75.7 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) NYN_YacP PF05991.11 KFQ94208.1 - 0.44 10.5 6.6 1.8 8.5 6.6 2.1 1 0 0 1 1 1 0 YacP-like NYN domain DEP PF00610.21 KFQ94209.1 - 1.4e-16 60.3 1.7 9.3e-16 57.6 0.2 2.7 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Tcp11 PF05794.13 KFQ94210.1 - 9e-111 371.1 0.0 1e-110 370.9 0.0 1.0 1 0 0 1 1 1 1 T-complex protein 11 DUF1819 PF08849.11 KFQ94210.1 - 0.086 12.6 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) EF_TS PF00889.19 KFQ94210.1 - 0.16 11.6 0.0 0.45 10.1 0.0 1.8 1 0 0 1 1 1 0 Elongation factor TS Suf PF05843.14 KFQ94211.1 - 2.3e-84 283.9 13.6 7.7e-83 278.9 0.2 5.1 4 2 1 5 5 5 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KFQ94211.1 - 3.8e-06 27.3 0.9 0.095 13.6 0.0 5.5 4 2 1 5 5 5 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KFQ94211.1 - 8.3e-06 25.1 13.2 0.24 10.5 0.1 5.7 3 2 4 7 7 7 5 NRDE-2, necessary for RNA interference TPR_6 PF13174.6 KFQ94211.1 - 0.0016 18.9 3.3 0.085 13.5 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ94211.1 - 0.0062 17.0 1.7 0.11 13.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ94211.1 - 0.098 13.3 0.6 0.58 10.9 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat HAT PF02184.16 KFQ94211.1 - 7.3 6.6 7.5 13 5.9 0.0 4.5 5 0 0 5 5 5 0 HAT (Half-A-TPR) repeat Pkinase PF00069.25 KFQ94212.1 - 1.2e-48 165.8 0.0 2.9e-48 164.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ94212.1 - 6e-24 84.7 0.0 1.1e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFQ94212.1 - 6.1e-06 25.7 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFQ94212.1 - 0.0028 16.5 0.7 0.0045 15.8 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFQ94212.1 - 0.0071 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFQ94212.1 - 0.086 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KFQ94212.1 - 0.13 11.8 0.2 3.4 7.3 0.1 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF3827 PF12877.7 KFQ94213.1 - 7.8e-293 973.0 6.2 7.8e-293 973.0 6.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3827) TSP_1 PF00090.19 KFQ94214.1 - 7.4e-87 285.4 86.6 2.5e-17 62.8 6.9 6.7 6 0 0 6 6 6 6 Thrombospondin type 1 domain Spond_N PF06468.13 KFQ94214.1 - 1.2e-71 240.8 0.2 2.7e-71 239.7 0.2 1.6 2 0 0 2 2 2 1 Spondin_N RVT_1 PF00078.27 KFQ94215.1 - 0.0087 15.6 0.1 0.016 14.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) C2 PF00168.30 KFQ94218.1 - 5.4e-53 177.6 0.1 9.2e-26 90.1 0.1 2.3 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 KFQ94218.1 - 0.0013 18.6 0.1 1.4 8.9 0.0 3.0 3 0 0 3 3 3 2 Phosphoinositide 3-kinase C2 CEP76-C2 PF15627.6 KFQ94218.1 - 0.026 14.1 0.0 4.1 6.9 0.0 2.3 2 0 0 2 2 2 0 CEP76 C2 domain OLF PF02191.16 KFQ94219.1 - 1.7e-78 263.6 0.0 2.2e-78 263.3 0.0 1.1 1 0 0 1 1 1 1 Olfactomedin-like domain DUF1088 PF06469.11 KFQ94219.1 - 0.11 12.2 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) SAM_1 PF00536.30 KFQ94220.1 - 2.2e-41 140.1 5.8 8.1e-19 67.8 0.0 4.1 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFQ94220.1 - 2.1e-39 133.4 3.4 4.3e-15 55.6 0.0 4.0 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) Myosin_tail_1 PF01576.19 KFQ94220.1 - 0.0018 16.2 30.7 0.0018 16.2 30.7 1.3 1 1 0 1 1 1 1 Myosin tail PKcGMP_CC PF16808.5 KFQ94220.1 - 0.016 15.1 1.7 0.016 15.1 1.7 4.9 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF16 PF01519.16 KFQ94220.1 - 0.021 15.3 1.7 0.021 15.3 1.7 3.2 3 1 0 3 3 2 0 Protein of unknown function DUF16 zf-C4H2 PF10146.9 KFQ94220.1 - 0.25 11.6 8.3 0.79 10.0 8.3 1.9 1 0 0 1 1 1 0 Zinc finger-containing protein SAM_PNT PF02198.16 KFQ94220.1 - 0.3 11.1 3.7 8.5 6.4 0.1 3.3 3 0 0 3 3 3 0 Sterile alpha motif (SAM)/Pointed domain HMMR_N PF15905.5 KFQ94220.1 - 0.39 10.2 36.4 0.036 13.5 12.0 2.3 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal WHEP-TRS PF00458.20 KFQ94220.1 - 0.63 10.2 4.7 0.5 10.6 0.1 2.8 2 1 0 2 2 2 0 WHEP-TRS domain ADIP PF11559.8 KFQ94220.1 - 1.4 9.0 29.5 14 5.8 17.9 3.4 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF1192 PF06698.11 KFQ94220.1 - 1.5 8.9 8.0 0.92 9.6 4.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) ERM PF00769.19 KFQ94220.1 - 6.8 6.4 37.6 0.76 9.5 25.6 2.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family NAD_binding_1 PF00175.21 KFQ94221.1 - 2e-36 124.9 0.0 3.8e-36 124.1 0.0 1.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KFQ94221.1 - 7.5e-34 116.0 0.0 1.3e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KFQ94221.1 - 1.1e-05 25.6 0.0 0.0002 21.5 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Trypsin PF00089.26 KFQ94222.1 - 1.7e-140 466.2 0.1 1.9e-72 243.7 0.0 2.2 2 0 0 2 2 2 2 Trypsin CUB PF00431.20 KFQ94222.1 - 5.8e-47 158.6 0.1 2.3e-24 85.8 0.0 2.4 2 0 0 2 2 2 2 CUB domain DUF1986 PF09342.11 KFQ94222.1 - 8e-21 74.6 0.2 1.7e-10 41.3 0.3 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 KFQ94222.1 - 2.1e-13 51.4 0.0 2.4e-05 25.3 0.0 2.9 2 1 0 2 2 2 2 Trypsin-like peptidase domain CUB_2 PF02408.20 KFQ94222.1 - 0.0011 18.7 0.0 0.32 10.8 0.0 2.6 2 0 0 2 2 2 2 CUB-like domain Peptidase_S29 PF02907.15 KFQ94222.1 - 0.44 10.3 2.4 11 5.8 0.2 2.5 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease NAD_binding_4 PF07993.12 KFQ94223.1 - 2.6e-77 259.5 0.0 3.3e-77 259.2 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 KFQ94223.1 - 9.9e-31 105.8 1.7 2.2e-30 104.7 1.7 1.6 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KFQ94223.1 - 1.2e-07 31.5 0.0 6.2e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFQ94223.1 - 7.7e-05 21.8 0.1 0.011 14.8 0.2 3.0 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KFQ94223.1 - 0.00014 21.1 0.0 0.0003 20.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 KFQ94223.1 - 0.00053 20.4 0.0 0.0011 19.3 0.0 1.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KFQ94223.1 - 0.0028 17.1 0.0 0.0067 15.9 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KFQ94223.1 - 0.027 14.4 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 KR domain Parathyroid PF01279.17 KFQ94224.1 - 1e-07 32.5 1.9 1.3e-07 32.2 1.9 1.2 1 0 0 1 1 1 1 Parathyroid hormone family BTB_3 PF16017.5 KFQ94225.1 - 1.5e-50 169.7 0.0 2.8e-50 168.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 KFQ94225.1 - 0.00069 19.9 0.0 0.0018 18.6 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain PAS_11 PF14598.6 KFQ94226.1 - 1.2e-26 93.1 0.4 9.3e-23 80.5 0.2 2.3 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 KFQ94226.1 - 5.7e-21 74.6 0.0 2.8e-09 37.0 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 KFQ94226.1 - 6.5e-20 71.2 0.0 8.5e-12 45.2 0.0 2.4 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 KFQ94226.1 - 2.5e-16 59.3 0.8 4.4e-16 58.6 0.8 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 KFQ94226.1 - 1.9e-08 34.5 0.0 7.9e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KFQ94226.1 - 2.9e-05 24.3 0.0 0.01 16.1 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.11 KFQ94226.1 - 0.025 15.3 0.0 0.091 13.4 0.0 1.9 2 0 0 2 2 2 0 PAS fold YBD PF17725.1 KFQ94227.1 - 7.8e-100 332.9 1.2 1e-99 332.5 1.2 1.2 1 0 0 1 1 1 1 YAP binding domain TEA PF01285.18 KFQ94227.1 - 2.3e-27 94.9 0.0 4.4e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 TEA/ATTS domain CH PF00307.31 KFQ94228.1 - 5e-35 120.0 3.2 2.5e-18 66.2 1.0 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFQ94228.1 - 1.3e-05 24.9 0.0 0.066 13.0 0.0 2.6 2 0 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.11 KFQ94228.1 - 2.4e-05 24.3 0.2 0.041 14.0 0.0 2.5 3 0 0 3 3 3 2 CH-like domain in sperm protein Sfi1 PF08457.10 KFQ94228.1 - 0.13 10.7 0.3 0.22 10.0 0.3 1.2 1 0 0 1 1 1 0 Sfi1 spindle body protein FlaG PF03646.15 KFQ94228.1 - 0.19 11.9 2.9 0.12 12.5 0.7 1.8 2 0 0 2 2 2 0 FlaG protein DUF3585 PF12130.8 KFQ94229.1 - 6.2e-42 143.0 26.4 6.2e-42 143.0 26.4 2.1 2 0 0 2 2 2 1 Bivalent Mical/EHBP Rab binding domain CH PF00307.31 KFQ94230.1 - 4.1e-22 78.4 0.0 2.2e-21 76.1 0.0 2.3 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFQ94230.1 - 1.1e-12 47.6 0.0 3e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 CAMSAP CH domain LIM PF00412.22 KFQ94230.1 - 1.5e-08 34.7 10.3 4.2e-08 33.3 10.3 1.8 1 0 0 1 1 1 1 LIM domain FAD_binding_3 PF01494.19 KFQ94230.1 - 5.9e-07 29.1 0.0 1.8e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFQ94230.1 - 1.3e-05 24.6 0.0 3.5e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFQ94230.1 - 4e-05 23.0 0.0 8e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFQ94230.1 - 0.00014 21.0 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KFQ94230.1 - 0.0006 18.6 0.0 0.0012 17.6 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KFQ94230.1 - 0.00068 20.2 0.1 0.0023 18.4 0.1 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KFQ94230.1 - 0.00081 19.8 0.0 0.0022 18.4 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding DAO PF01266.24 KFQ94230.1 - 0.0021 17.7 0.0 0.0043 16.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFQ94230.1 - 0.0045 17.2 0.0 0.0098 16.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KFQ94230.1 - 0.025 13.9 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFQ94230.1 - 0.028 13.5 0.0 0.067 12.2 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 KFQ94230.1 - 0.086 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 KFQ94230.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KFQ94230.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Dickkopf_N PF04706.12 KFQ94231.1 - 2.1e-15 56.9 20.0 2.1e-15 56.9 20.0 3.1 3 0 0 3 3 3 2 Dickkopf N-terminal cysteine-rich region Prokineticin PF06607.11 KFQ94231.1 - 1e-05 25.8 3.3 1e-05 25.8 3.3 2.7 1 1 2 3 3 3 1 Prokineticin Conotoxin_I2 PF17557.2 KFQ94231.1 - 0.022 14.9 6.5 0.022 14.9 6.5 3.5 3 1 1 4 4 4 0 I2-superfamily conotoxins UCH PF00443.29 KFQ94232.1 - 2.5e-49 168.1 0.8 5.8e-49 166.9 0.8 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFQ94232.1 - 8.3e-39 134.0 1.6 2.2e-38 132.7 1.6 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_2 PF14560.6 KFQ94232.1 - 4.1e-08 33.6 0.1 0.11 13.0 0.0 4.1 3 0 0 3 3 3 3 Ubiquitin-like domain ubiquitin PF00240.23 KFQ94232.1 - 5.3e-07 29.3 0.1 0.16 11.8 0.0 3.9 3 0 0 3 3 3 2 Ubiquitin family DUF4487 PF14868.6 KFQ94232.1 - 0.023 13.6 0.2 0.043 12.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4487) Sad1_UNC PF07738.13 KFQ94232.1 - 0.04 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal UN_NPL4 PF11543.8 KFQ94232.1 - 0.088 13.3 0.4 19 5.9 0.0 3.4 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 Glycos_transf_2 PF00535.26 KFQ94234.1 - 2.7e-24 85.9 0.1 3.6e-24 85.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 KFQ94234.1 - 0.00027 20.5 0.0 0.00071 19.2 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Ricin_B_lectin PF00652.22 KFQ94234.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain MIF4G PF02854.19 KFQ94236.1 - 7.5e-58 195.6 1.7 7.5e-58 195.6 1.7 2.2 2 0 0 2 2 2 1 MIF4G domain W2 PF02020.18 KFQ94236.1 - 1.2e-20 73.4 1.6 3.5e-20 71.9 1.0 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon MA3 PF02847.17 KFQ94236.1 - 4.1e-13 49.3 0.2 4.1e-13 49.3 0.2 3.0 3 0 0 3 3 3 1 MA3 domain MRVI1 PF05781.12 KFQ94237.1 - 5.4e-220 731.6 14.3 7.9e-220 731.1 14.3 1.2 1 0 0 1 1 1 1 MRVI1 protein PEP-utilisers_N PF05524.13 KFQ94237.1 - 0.6 10.3 4.2 1.5 9.0 2.4 2.5 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Xlink PF00193.17 KFQ94238.1 - 4.8e-20 71.7 0.1 9.4e-20 70.8 0.1 1.5 1 0 0 1 1 1 1 Extracellular link domain DAG1 PF05454.11 KFQ94238.1 - 0.0013 18.2 1.4 0.0021 17.5 0.4 1.7 1 1 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Comm PF15957.5 KFQ94238.1 - 0.012 15.9 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 Commissureless DUF4834 PF16118.5 KFQ94238.1 - 0.014 16.3 0.1 0.03 15.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) vMSA PF00695.19 KFQ94238.1 - 0.015 14.4 0.4 0.022 13.9 0.4 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus DUF4446 PF14584.6 KFQ94238.1 - 0.016 15.2 0.3 0.028 14.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) OSTbeta PF15048.6 KFQ94238.1 - 0.027 14.6 0.2 0.06 13.5 0.2 1.6 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein MFS_Mycoplasma PF07672.13 KFQ94238.1 - 0.035 13.4 0.1 0.049 12.9 0.1 1.2 1 0 0 1 1 1 0 Mycoplasma MFS transporter Nucleoside_tran PF01733.18 KFQ94238.1 - 0.063 12.7 0.3 0.1 12.0 0.3 1.3 1 0 0 1 1 1 0 Nucleoside transporter Phage_holin_3_6 PF07332.11 KFQ94238.1 - 0.078 13.0 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III STT3 PF02516.14 KFQ94238.1 - 0.079 11.9 0.2 0.11 11.4 0.2 1.1 1 0 0 1 1 1 0 Oligosaccharyl transferase STT3 subunit Folate_carrier PF01770.18 KFQ94238.1 - 0.11 11.2 0.5 0.16 10.6 0.5 1.1 1 0 0 1 1 1 0 Reduced folate carrier TT_ORF1 PF02956.14 KFQ94238.1 - 0.15 10.7 1.2 0.23 10.1 1.2 1.1 1 0 0 1 1 1 0 TT viral orf 1 zf-C3HC4_3 PF13920.6 KFQ94239.1 - 4e-10 39.4 11.2 6.5e-10 38.7 11.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ94239.1 - 2.6e-09 37.2 15.2 4.9e-09 36.4 15.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFQ94239.1 - 7.9e-09 35.2 14.8 1.4e-08 34.4 14.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFQ94239.1 - 5.5e-07 29.3 12.0 1.2e-06 28.2 12.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFQ94239.1 - 5.9e-06 26.1 13.9 1.2e-05 25.1 13.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFQ94239.1 - 3.8e-05 23.6 12.0 9.2e-05 22.4 12.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFQ94239.1 - 0.001 19.0 15.8 0.0097 15.9 15.5 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFQ94239.1 - 0.0028 17.9 14.9 0.0081 16.4 14.9 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain Gp138_N PF18352.1 KFQ94239.1 - 0.029 14.4 0.2 1.6 8.8 0.1 2.4 2 0 0 2 2 2 0 Phage protein Gp138 N-terminal domain zf-C3HC4_4 PF15227.6 KFQ94239.1 - 0.043 14.0 13.0 0.083 13.1 12.3 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KFQ94239.1 - 0.22 11.4 11.9 0.45 10.3 11.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KFQ94239.1 - 1.1 9.3 10.5 2.3 8.3 9.7 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KFQ94239.1 - 4.2 7.2 16.1 2.5 7.9 12.9 2.3 2 1 0 2 2 2 0 RING-like zinc finger A_deaminase PF00962.22 KFQ94240.1 - 3.7e-133 443.9 0.0 1e-132 442.4 0.0 1.7 1 1 0 1 1 1 1 Adenosine/AMP deaminase Calc_CGRP_IAPP PF00214.19 KFQ94241.1 - 5.4e-24 84.9 0.0 6.8e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Calcitonin / CGRP / IAPP family Pkinase PF00069.25 KFQ94242.1 - 3.9e-54 183.8 0.0 5e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ94242.1 - 2.3e-21 76.3 0.0 2.9e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_M74 PF03411.13 KFQ94242.1 - 0.11 12.1 0.3 1.4 8.4 0.0 2.5 3 0 0 3 3 3 0 Penicillin-insensitive murein endopeptidase zf-H2C2_2 PF13465.6 KFQ94243.1 - 1.3e-35 120.3 50.4 9.2e-08 32.2 0.5 7.7 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ94243.1 - 2.8e-30 103.1 47.6 2.3e-06 27.7 1.2 7.4 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ94243.1 - 2.4e-19 68.4 43.6 0.0029 18.3 0.6 7.5 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFQ94243.1 - 1.2e-06 28.7 16.2 0.021 15.1 5.0 3.5 1 1 3 4 4 4 4 C2H2-type zinc ribbon CopK PF11525.8 KFQ94243.1 - 1.8e-06 27.5 3.6 1.6 8.4 0.0 6.0 4 2 2 6 6 6 2 Copper resistance protein K zf-C2H2_jaz PF12171.8 KFQ94243.1 - 3.2e-05 24.1 16.7 1.2 9.5 0.5 6.6 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 KFQ94243.1 - 0.00018 21.7 25.3 0.084 13.0 0.3 6.1 1 1 4 6 6 6 3 Aberrant zinc-finger FOXP-CC PF16159.5 KFQ94243.1 - 0.0011 19.5 17.1 0.28 11.8 0.9 6.9 3 3 4 7 7 7 1 FOXP coiled-coil domain zf-TRAF PF02176.18 KFQ94243.1 - 0.019 15.7 1.4 0.019 15.7 1.4 3.8 2 2 2 4 4 4 0 TRAF-type zinc finger IBN_N PF03810.19 KFQ94244.1 - 2.8e-19 68.8 0.1 1.4e-17 63.4 0.0 3.7 3 1 1 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.10 KFQ94244.1 - 5.2e-08 32.1 1.0 5.2e-08 32.1 1.0 2.6 2 1 0 2 2 2 1 Cse1 Xpo1 PF08389.12 KFQ94244.1 - 0.00027 21.0 8.0 0.00068 19.7 0.9 4.2 4 1 1 5 5 5 1 Exportin 1-like protein RIX1 PF08167.12 KFQ94244.1 - 0.004 16.9 0.8 1.2 8.8 0.1 3.9 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis DUF3730 PF12530.8 KFQ94244.1 - 0.025 14.2 2.1 0.035 13.7 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3730) RRN3 PF05327.11 KFQ94244.1 - 0.21 10.1 13.0 1.8 7.0 0.0 3.3 3 0 0 3 3 3 0 RNA polymerase I specific transcription initiation factor RRN3 FYDLN_acid PF09538.10 KFQ94244.1 - 1 10.1 10.2 2.2 9.0 10.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF2457 PF10446.9 KFQ94244.1 - 6.6 5.8 16.2 9.7 5.2 16.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CobT PF06213.12 KFQ94244.1 - 6.8 6.0 11.1 12 5.2 9.2 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT SNARE_assoc PF09335.11 KFQ94245.1 - 3.5e-22 79.1 6.1 3.5e-22 79.1 6.1 2.6 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF5305 PF17231.2 KFQ94245.1 - 0.14 11.5 0.1 0.78 9.1 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5305) TMEM208_SND2 PF05620.11 KFQ94245.1 - 0.32 10.7 5.7 0.54 10.0 0.9 2.6 2 1 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Oleosin PF01277.17 KFQ94245.1 - 0.33 10.7 0.0 0.33 10.7 0.0 2.8 2 1 1 3 3 3 0 Oleosin DENN PF02141.21 KFQ94246.1 - 3.9e-61 206.3 5.6 4.7e-61 206.0 4.3 1.8 2 0 0 2 2 2 1 DENN (AEX-3) domain RUN PF02759.19 KFQ94246.1 - 7.1e-40 136.1 5.3 1.3e-19 70.5 2.0 2.7 2 0 0 2 2 2 2 RUN domain dDENN PF03455.19 KFQ94246.1 - 1.8e-19 69.4 1.9 1.8e-19 69.4 1.9 3.1 3 0 0 3 3 3 1 dDENN domain uDENN PF03456.18 KFQ94246.1 - 9.1e-15 55.2 0.0 9.1e-15 55.2 0.0 2.2 3 0 0 3 3 3 1 uDENN domain PLAT PF01477.23 KFQ94246.1 - 9.1e-15 55.2 0.0 2.7e-14 53.7 0.0 1.9 2 0 0 2 2 2 1 PLAT/LH2 domain Asp_protease PF09668.10 KFQ94247.1 - 2.2e-09 37.1 0.0 5.2e-09 36.0 0.0 1.6 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFQ94247.1 - 3.9e-08 33.7 0.0 8.3e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFQ94247.1 - 1.7e-05 25.4 0.0 5.3e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KFQ94247.1 - 0.099 12.4 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 Retroviral aspartyl protease Tmemb_9 PF05434.11 KFQ94248.1 - 1.6e-49 167.6 0.4 2.7e-49 166.8 0.4 1.4 1 0 0 1 1 1 1 TMEM9 HLH PF00010.26 KFQ94249.1 - 2.6e-16 59.3 3.1 3.4e-16 58.9 3.1 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Cas9-BH PF16593.5 KFQ94249.1 - 0.02 14.6 0.4 0.046 13.4 0.4 1.5 1 0 0 1 1 1 0 Bridge helix of CRISPR-associated endonuclease Cas9 DUF4537 PF15057.6 KFQ94250.1 - 7.2e-28 97.0 0.0 1.1e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) DENN PF02141.21 KFQ94251.1 - 1.3e-58 198.1 0.7 1.3e-58 198.1 0.7 2.0 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 KFQ94251.1 - 7.5e-17 61.8 0.1 2.2e-16 60.3 0.1 1.9 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KFQ94251.1 - 2.7e-11 43.3 2.3 8.2e-11 41.7 2.3 1.9 1 0 0 1 1 1 1 dDENN domain Ribosomal_L27A PF00828.19 KFQ94252.1 - 1.8e-25 90.1 0.0 2e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A LIM PF00412.22 KFQ94253.1 - 2.4e-30 104.5 21.9 3.8e-15 55.9 8.1 2.0 2 0 0 2 2 2 2 LIM domain RIC3 PF15361.6 KFQ94254.1 - 7.2e-32 110.8 0.0 2.6e-31 109.0 0.0 1.9 2 0 0 2 2 2 1 Resistance to inhibitors of cholinesterase homologue 3 7TMR-HDED PF07697.11 KFQ94254.1 - 0.0083 16.3 0.5 0.014 15.6 0.5 1.4 1 1 0 1 1 1 1 7TM-HD extracellular DUF1664 PF07889.12 KFQ94254.1 - 0.0092 16.0 0.0 0.026 14.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) ParB PF08775.10 KFQ94254.1 - 0.035 14.6 0.4 0.091 13.2 0.4 1.7 1 0 0 1 1 1 0 ParB family Tub PF01167.18 KFQ94255.1 - 1.2e-95 319.8 0.0 1.2e-95 319.8 0.0 2.0 2 1 0 2 2 2 1 Tub family Tub_N PF16322.5 KFQ94255.1 - 7e-64 216.1 26.5 1e-63 215.6 26.5 1.2 1 0 0 1 1 1 1 Tubby N-terminal UpxZ PF06603.11 KFQ94255.1 - 0.21 11.9 0.7 15 5.9 0.1 2.9 2 2 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists RVT_1 PF00078.27 KFQ94256.1 - 0.081 12.4 0.1 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) EMP24_GP25L PF01105.24 KFQ94257.1 - 2.2e-44 151.6 0.1 2.4e-44 151.4 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Tyr_Deacylase PF02580.16 KFQ94258.1 - 3.7e-44 150.8 0.0 4.5e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase RNA_pol_Rpc34 PF05158.12 KFQ94260.1 - 1.8e-103 346.5 0.3 2.2e-103 346.2 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit TrmB PF01978.19 KFQ94260.1 - 0.00017 21.4 0.6 0.01 15.7 0.1 2.9 2 1 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB RPA_C PF08784.11 KFQ94260.1 - 0.0035 18.0 0.9 1.2 9.9 0.0 3.2 3 0 0 3 3 3 1 Replication protein A C terminal TFIIE_alpha PF02002.17 KFQ94260.1 - 0.048 13.5 0.4 0.12 12.2 0.4 1.8 1 0 0 1 1 1 0 TFIIE alpha subunit Acetyltransf_1 PF00583.25 KFQ94261.1 - 5.1e-10 39.6 0.0 1.1e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFQ94261.1 - 1.3e-09 38.1 0.0 2.9e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFQ94261.1 - 6.3e-08 32.9 0.1 1.7e-07 31.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFQ94261.1 - 6.3e-05 22.9 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KFQ94261.1 - 0.0019 18.2 0.0 0.0039 17.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KFQ94261.1 - 0.0079 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase zf_UBZ PF18439.1 KFQ94261.1 - 1.3 8.6 4.1 1.1 8.9 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger PET117 PF15786.5 KFQ94262.1 - 1.2e-07 31.9 2.6 1.5e-07 31.5 2.6 1.2 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial zf-H2C2_2 PF13465.6 KFQ94263.1 - 7.2e-18 64.1 22.7 2.1e-09 37.3 0.6 5.2 5 1 0 5 5 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ94263.1 - 9.3e-18 63.6 26.3 5.3e-05 23.5 2.5 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ94263.1 - 2.6e-11 43.3 25.4 0.00039 21.0 1.7 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KFQ94263.1 - 1e-07 32.7 13.0 8.5e-06 26.5 0.4 3.0 2 1 1 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 KFQ94263.1 - 5.8e-06 26.4 9.6 0.39 11.1 0.3 3.7 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFQ94263.1 - 6e-05 23.3 15.8 0.00093 19.5 2.4 4.4 3 1 1 4 4 4 1 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 KFQ94263.1 - 0.00039 20.0 0.0 0.00039 20.0 0.0 2.8 2 1 1 3 3 3 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_5 PF13909.6 KFQ94263.1 - 0.0047 16.6 20.1 0.14 11.9 0.2 5.3 4 2 1 5 5 5 1 C2H2-type zinc-finger domain FYVE PF01363.21 KFQ94263.1 - 0.0064 16.6 19.8 0.22 11.7 10.3 2.6 1 1 1 2 2 2 2 FYVE zinc finger zf-C2H2_6 PF13912.6 KFQ94263.1 - 0.022 14.7 20.5 0.9 9.6 3.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFQ94263.1 - 0.074 12.8 1.2 0.074 12.8 1.2 3.9 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_12 PF18658.1 KFQ94263.1 - 0.094 12.3 0.0 0.094 12.3 0.0 3.3 1 1 3 4 4 4 0 Zinc-finger C2H2-type DUF2256 PF10013.9 KFQ94263.1 - 0.25 11.5 6.7 6.8 6.9 0.4 3.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-MYST PF17772.1 KFQ94263.1 - 0.35 10.5 12.7 5.3 6.7 0.1 4.1 4 0 0 4 4 4 0 MYST family zinc finger domain Rpr2 PF04032.16 KFQ94263.1 - 0.51 10.7 14.8 2.5 8.5 3.5 3.4 3 1 1 4 4 4 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zinc_ribbon_15 PF17032.5 KFQ94263.1 - 0.56 11.0 11.8 0.67 10.7 1.5 2.3 1 1 1 2 2 2 0 zinc-ribbon family zf-C2H2_2 PF12756.7 KFQ94263.1 - 0.59 10.5 15.7 2.7 8.4 0.4 3.7 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) C5HCH PF17982.1 KFQ94263.1 - 0.65 10.2 11.4 3.9 7.7 0.1 3.5 3 0 0 3 3 3 0 NSD Cys-His rich domain Zn-ribbon_8 PF09723.10 KFQ94263.1 - 0.76 10.0 17.6 5.4 7.2 0.4 4.4 3 1 1 4 4 4 0 Zinc ribbon domain A2L_zn_ribbon PF08792.10 KFQ94263.1 - 0.78 9.5 0.1 0.78 9.5 0.1 3.7 4 0 0 4 4 4 0 A2L zinc ribbon domain XPA_N PF01286.18 KFQ94263.1 - 1.1 9.4 9.9 41 4.3 0.2 4.2 4 0 0 4 4 4 0 XPA protein N-terminal zf_UBZ PF18439.1 KFQ94263.1 - 1.8 8.2 10.7 9.9 5.9 0.6 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger ADK_lid PF05191.14 KFQ94263.1 - 4 7.5 11.2 0.45 10.5 1.6 3.4 3 1 0 3 3 3 0 Adenylate kinase, active site lid zf-dskA_traR PF01258.17 KFQ94263.1 - 4.3 7.4 7.9 9.2 6.3 0.0 3.7 4 0 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger PDDEXK_1 PF12705.7 KFQ94264.1 - 5.7e-08 33.0 0.1 4.4e-07 30.1 0.1 2.2 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily PX PF00787.24 KFQ94265.1 - 1.6e-19 70.0 0.3 1.6e-19 70.0 0.3 2.8 3 1 0 3 3 3 1 PX domain Vps5 PF09325.10 KFQ94265.1 - 5.7e-17 62.1 18.6 8.8e-16 58.2 13.8 2.5 2 1 0 2 2 2 1 Vps5 C terminal like IpaC_SipC PF09599.10 KFQ94265.1 - 0.067 12.7 1.2 0.15 11.5 1.1 1.6 1 1 0 1 1 1 0 Salmonella-Shigella invasin protein C (IpaC_SipC) Glyco_hydro_97 PF10566.9 KFQ94265.1 - 0.11 11.8 0.2 0.17 11.1 0.2 1.4 1 0 0 1 1 1 0 Glycoside hydrolase 97 LcrG PF07216.12 KFQ94265.1 - 0.14 12.1 0.5 8.1 6.4 0.0 3.0 3 0 0 3 3 3 0 LcrG protein BLYB PF05289.11 KFQ94265.1 - 0.28 11.4 6.8 0.29 11.4 1.9 2.9 1 1 1 2 2 2 0 Borrelia hemolysin accessory protein Cofilin_ADF PF00241.20 KFQ94266.1 - 2.1e-32 111.5 0.2 2.6e-32 111.1 0.2 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cystatin PF00031.21 KFQ94267.1 - 9.9e-27 93.0 0.0 1.1e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 KFQ94267.1 - 1.6e-05 25.1 0.1 3.6e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Aspartic acid proteinase inhibitor CD225 PF04505.12 KFQ94268.1 - 1.4e-18 66.8 0.1 2.2e-18 66.1 0.1 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein Ank_2 PF12796.7 KFQ94269.1 - 2.3e-30 105.0 3.5 1.8e-15 57.2 1.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ94269.1 - 4.3e-30 103.7 6.2 4.5e-14 52.6 0.6 5.3 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 KFQ94269.1 - 4.2e-27 93.4 14.5 2.2e-08 34.2 0.6 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KFQ94269.1 - 5.1e-24 84.0 16.0 8.6e-12 45.0 2.3 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ94269.1 - 2.7e-20 70.3 6.1 8.9e-05 22.6 0.2 4.6 4 0 0 4 4 4 4 Ankyrin repeat FAM83 PF07894.12 KFQ94270.1 - 1.4e-76 257.6 0.0 2e-76 257.2 0.0 1.2 1 0 0 1 1 1 1 FAM83 A-H PLDc_2 PF13091.6 KFQ94270.1 - 2.3e-07 30.8 0.0 5.4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 PLD-like domain FAM83 PF07894.12 KFQ94271.1 - 3.4e-37 128.5 0.3 1.6e-24 87.0 0.3 2.1 1 1 1 2 2 2 2 FAM83 A-H Gcd10p PF04189.13 KFQ94271.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.4 1 1 0 1 1 1 0 Gcd10p family HA2 PF04408.23 KFQ94272.1 - 1.2e-20 73.7 0.0 3.4e-20 72.3 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFQ94272.1 - 1.5e-19 70.1 0.0 3.4e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFQ94272.1 - 6.7e-12 45.7 0.0 1.5e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ABC_tran PF00005.27 KFQ94272.1 - 0.00014 22.4 0.2 0.037 14.6 0.1 2.6 1 1 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 KFQ94272.1 - 0.00034 20.9 0.3 0.0015 18.8 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFQ94272.1 - 0.016 14.9 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KFQ94272.1 - 0.042 14.2 0.1 0.18 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFQ94272.1 - 0.08 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Topoisom_I PF01028.20 KFQ94273.1 - 3.3e-103 343.9 3.6 3.3e-103 343.9 3.6 2.7 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KFQ94273.1 - 3.7e-101 337.1 8.3 3.7e-101 337.1 8.3 5.3 4 1 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KFQ94273.1 - 1.3e-33 114.8 0.5 1.3e-33 114.8 0.5 3.0 2 0 0 2 2 2 1 C-terminal topoisomerase domain Arg_decarbox_C PF17944.1 KFQ94273.1 - 0.26 11.9 1.5 1.1 9.8 1.5 2.2 1 0 0 1 1 1 0 Arginine decarboxylase C-terminal helical extension PI-PLC-X PF00388.19 KFQ94274.1 - 8.3e-66 220.0 0.4 2e-65 218.8 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain SH2 PF00017.24 KFQ94274.1 - 8.2e-48 160.4 1.1 2.1e-24 85.4 0.0 3.4 3 0 0 3 3 3 2 SH2 domain PI-PLC-Y PF00387.19 KFQ94274.1 - 2.8e-40 137.3 0.0 6.8e-40 136.0 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain SH3_1 PF00018.28 KFQ94274.1 - 4.1e-16 58.3 0.6 1.2e-15 56.9 0.6 1.8 1 0 0 1 1 1 1 SH3 domain C2 PF00168.30 KFQ94274.1 - 2.1e-14 53.7 0.0 6.6e-14 52.1 0.0 1.9 1 0 0 1 1 1 1 C2 domain PH PF00169.29 KFQ94274.1 - 6.5e-12 45.9 0.1 0.008 16.7 0.0 4.1 4 0 0 4 4 3 3 PH domain SH3_9 PF14604.6 KFQ94274.1 - 2.7e-10 39.9 0.1 2.7e-10 39.9 0.1 2.2 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.17 KFQ94274.1 - 6.6e-09 35.3 0.1 1.4e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain GDPD PF03009.17 KFQ94274.1 - 0.00034 20.4 0.0 0.0015 18.3 0.0 2.0 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family PH_12 PF16457.5 KFQ94274.1 - 0.0042 17.6 0.0 0.012 16.2 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain EF-hand_6 PF13405.6 KFQ94274.1 - 0.12 12.4 0.0 2.8 8.1 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain LNS2 PF08235.13 KFQ94275.1 - 3e-106 354.0 0.0 4.8e-106 353.3 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KFQ94275.1 - 1.4e-41 140.6 0.0 2.4e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 KFQ94275.1 - 9.9e-34 115.5 0.0 1.9e-33 114.6 0.0 1.5 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain EMI PF07546.13 KFQ94276.1 - 2.6e-16 60.1 6.4 2.6e-16 60.1 6.4 2.0 2 0 0 2 2 1 1 EMI domain DUF5082 PF16888.5 KFQ94276.1 - 1.2e-08 35.3 16.3 0.0096 16.2 0.0 6.4 4 2 1 5 5 5 2 Domain of unknown function (DUF5082) DUF1664 PF07889.12 KFQ94276.1 - 2.9e-08 33.8 19.5 0.01 15.9 1.1 7.3 4 2 3 8 8 8 2 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 KFQ94276.1 - 4.5e-05 23.4 16.6 0.23 11.3 0.2 5.8 2 1 3 5 5 5 3 Apolipoprotein A1/A4/E domain Spc7 PF08317.11 KFQ94276.1 - 0.00025 20.1 21.6 0.11 11.4 0.0 4.6 3 1 2 5 5 5 3 Spc7 kinetochore protein Fib_alpha PF08702.10 KFQ94276.1 - 0.00039 20.6 22.6 0.01 16.0 3.2 6.4 3 2 2 5 5 5 1 Fibrinogen alpha/beta chain family CorA PF01544.18 KFQ94276.1 - 0.00062 19.2 3.7 0.00062 19.2 3.7 3.8 3 2 1 4 4 4 2 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 KFQ94276.1 - 0.00062 19.8 18.2 2.9 7.9 3.6 6.9 2 1 5 7 7 7 1 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.6 KFQ94276.1 - 0.00076 19.9 19.5 2.4 8.6 0.0 6.8 6 1 0 6 6 6 1 Snapin/Pallidin NPV_P10 PF05531.12 KFQ94276.1 - 0.0013 19.2 17.5 11 6.5 1.3 8.4 6 1 3 10 10 9 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 KFQ94276.1 - 0.0024 18.2 22.4 6.9 7.1 0.1 10.1 7 3 5 12 12 11 0 Flagella accessory protein C (FlaC) Exonuc_VII_L PF02601.15 KFQ94276.1 - 0.0039 16.8 9.4 0.74 9.3 0.2 3.3 2 1 0 2 2 2 2 Exonuclease VII, large subunit Golgin_A5 PF09787.9 KFQ94276.1 - 0.0054 16.2 2.3 0.0054 16.2 2.3 3.9 3 1 1 5 5 5 1 Golgin subfamily A member 5 Fzo_mitofusin PF04799.13 KFQ94276.1 - 0.009 15.6 3.0 0.009 15.6 3.0 4.7 3 1 2 5 5 5 1 fzo-like conserved region TACC_C PF05010.14 KFQ94276.1 - 0.015 15.1 13.9 0.096 12.5 1.0 3.6 3 1 1 4 4 4 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal COG2 PF06148.11 KFQ94276.1 - 0.025 14.6 17.6 0.29 11.2 0.9 6.1 4 3 0 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 Sugarporin_N PF11471.8 KFQ94276.1 - 0.034 14.1 0.1 0.17 11.8 0.1 2.2 2 0 0 2 2 1 0 Maltoporin periplasmic N-terminal extension WXG100 PF06013.12 KFQ94276.1 - 0.046 14.0 5.2 12 6.3 0.0 6.5 6 3 1 7 7 7 0 Proteins of 100 residues with WXG TPR_MLP1_2 PF07926.12 KFQ94276.1 - 0.056 13.5 26.1 0.12 12.4 3.7 6.1 4 2 2 7 7 7 0 TPR/MLP1/MLP2-like protein HrpB7 PF09486.10 KFQ94276.1 - 0.062 13.7 9.1 8.2 6.8 0.1 5.3 2 1 3 6 6 6 0 Bacterial type III secretion protein (HrpB7) OmpH PF03938.14 KFQ94276.1 - 0.064 13.6 4.7 37 4.6 0.0 4.2 4 0 0 4 4 4 0 Outer membrane protein (OmpH-like) Corona_S2 PF01601.16 KFQ94276.1 - 0.085 11.3 6.3 1.5 7.2 0.3 3.6 3 1 1 4 4 4 0 Coronavirus S2 glycoprotein ApoO PF09769.9 KFQ94276.1 - 0.16 11.9 1.0 21 5.1 0.2 3.8 3 1 0 3 3 3 0 Apolipoprotein O Bacillus_HBL PF05791.11 KFQ94276.1 - 0.26 11.1 9.6 1.4 8.7 0.7 4.8 4 2 1 6 6 6 0 Bacillus haemolytic enterotoxin (HBL) HCMV_UL139 PF12507.8 KFQ94276.1 - 0.27 11.6 7.2 5.9 7.3 0.1 4.0 3 1 1 5 5 5 0 Human Cytomegalovirus UL139 protein PMEI PF04043.15 KFQ94276.1 - 0.34 11.3 7.6 5 7.5 0.1 3.7 3 1 1 4 4 4 0 Plant invertase/pectin methylesterase inhibitor DUF16 PF01519.16 KFQ94276.1 - 0.49 10.9 18.8 12 6.5 1.5 6.1 5 2 1 6 6 6 0 Protein of unknown function DUF16 Trimer_CC PF08954.11 KFQ94276.1 - 2.9 7.5 13.9 2.2 7.9 0.2 4.3 5 0 0 5 5 4 0 Trimerisation motif DASH_Dam1 PF08653.10 KFQ94276.1 - 3.2 7.6 9.2 56 3.7 0.0 5.9 8 0 0 8 8 7 0 DASH complex subunit Dam1 Lectin_N PF03954.14 KFQ94276.1 - 5.8 6.7 15.2 2.5 7.9 0.8 4.8 3 1 3 6 6 6 0 Hepatic lectin, N-terminal domain Spc24 PF08286.11 KFQ94276.1 - 9.7 6.5 20.0 5.1 7.4 0.1 6.5 5 1 1 6 6 6 0 Spc24 subunit of Ndc80 Tropomyosin PF00261.20 KFQ94276.1 - 9.8 5.5 19.5 0.28 10.5 4.7 4.2 2 1 1 3 3 3 0 Tropomyosin Ribophorin_II PF05817.14 KFQ94277.1 - 4.7e-228 758.8 5.1 5.3e-228 758.7 5.1 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Hormone_2 PF00123.20 KFQ94278.1 - 5e-15 55.1 0.3 3.4e-14 52.4 0.1 2.1 2 0 0 2 2 2 1 Peptide hormone UPF0239 PF06783.11 KFQ94279.1 - 1.5e-24 85.9 0.0 1.8e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0239) Pkinase_Tyr PF07714.17 KFQ94280.1 - 6.8e-93 310.7 0.0 8.6e-93 310.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ94280.1 - 9.7e-47 159.5 0.0 1.6e-46 158.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFQ94280.1 - 2.6e-27 94.7 0.1 5.2e-27 93.7 0.1 1.5 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 KFQ94280.1 - 0.00013 21.7 0.6 0.00044 20.0 0.1 2.2 3 0 0 3 3 3 1 Variant SH3 domain SH3_1 PF00018.28 KFQ94280.1 - 0.00036 20.1 0.2 0.0038 16.8 0.1 2.4 2 0 0 2 2 2 1 SH3 domain Haspin_kinase PF12330.8 KFQ94280.1 - 0.0027 16.7 0.0 0.0063 15.5 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain SH3_2 PF07653.17 KFQ94280.1 - 0.0072 16.0 0.1 0.024 14.3 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain APH PF01636.23 KFQ94280.1 - 0.12 12.3 0.0 0.76 9.6 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family BC10 PF06726.12 KFQ94281.1 - 5.3e-27 93.8 10.2 6.8e-27 93.5 10.2 1.2 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Gpi16 PF04113.14 KFQ94282.1 - 2.2e-146 488.6 1.2 2.8e-145 485.0 1.2 1.9 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Dysbindin PF04440.16 KFQ94283.1 - 3.1e-49 166.9 6.2 3.6e-49 166.7 6.2 1.0 1 0 0 1 1 1 1 Dysbindin (Dystrobrevin binding protein 1) SYS1 PF09801.9 KFQ94284.1 - 5.7e-49 166.0 2.8 6.3e-49 165.8 2.8 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Syndecan PF01034.20 KFQ94285.1 - 7.9e-25 86.6 0.2 1.2e-24 86.0 0.2 1.3 1 0 0 1 1 1 1 Syndecan domain Protocadherin PF08374.11 KFQ94285.1 - 0.053 13.5 0.0 0.068 13.1 0.0 1.2 1 0 0 1 1 1 0 Protocadherin DUF2407_C PF13373.6 KFQ94285.1 - 0.18 12.0 0.0 0.26 11.4 0.0 1.3 1 1 0 1 1 1 0 DUF2407 C-terminal domain TH1 PF04858.13 KFQ94286.1 - 1.2e-281 935.5 0.7 1.4e-281 935.3 0.7 1.0 1 0 0 1 1 1 1 TH1 protein Peptidase_C1 PF00112.23 KFQ94287.1 - 3e-39 135.4 7.1 3.8e-39 135.0 7.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KFQ94287.1 - 0.047 12.5 0.3 0.14 10.9 0.3 1.6 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 KFQ94288.1 - 9.2e-46 156.7 10.3 1.1e-45 156.4 10.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Tubulin PF00091.25 KFQ94289.1 - 1.1e-70 237.9 0.0 1.5e-70 237.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFQ94289.1 - 1.6e-40 138.2 0.0 2.6e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KFQ94289.1 - 2.7e-05 24.4 0.0 6.2e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KFQ94289.1 - 0.0047 16.2 0.0 0.0076 15.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin like Tubulin_3 PF14881.6 KFQ94289.1 - 0.0047 16.6 0.0 0.0091 15.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain ATP-synt_Eps PF04627.13 KFQ94290.1 - 5.3e-19 67.9 3.6 5.8e-19 67.8 3.6 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain UPF0556 PF10572.9 KFQ94290.1 - 0.11 12.0 0.2 0.11 12.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0556 PRELI PF04707.14 KFQ94291.1 - 4e-56 189.2 0.1 4.7e-56 188.9 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family Endothelin PF00322.17 KFQ94295.1 - 0.011 15.3 4.0 0.011 15.3 4.0 1.7 2 0 0 2 2 2 0 Endothelin family RPEL PF02755.15 KFQ94296.1 - 5.8e-21 73.5 21.3 9.7e-07 28.3 3.2 4.7 4 0 0 4 4 4 4 RPEL repeat Sod_Ni PF09055.11 KFQ94296.1 - 0.016 15.8 1.0 0.05 14.2 1.0 1.8 1 0 0 1 1 1 0 Nickel-containing superoxide dismutase CBM_21 PF03370.13 KFQ94297.1 - 6.4e-33 113.3 0.2 9.4e-33 112.8 0.2 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KFQ94297.1 - 4.2e-14 52.9 0.4 9.1e-14 51.8 0.4 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) CBM_25 PF03423.13 KFQ94297.1 - 0.016 15.5 0.0 0.028 14.6 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) FAM217 PF15344.6 KFQ94299.1 - 3.2e-88 295.7 1.7 4.6e-88 295.2 1.7 1.2 1 0 0 1 1 1 1 FAM217 family DUF4125 PF13526.6 KFQ94299.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4125) Cadherin PF00028.17 KFQ94300.1 - 1.7e-86 284.8 5.6 5.6e-22 78.0 0.9 5.4 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFQ94300.1 - 1.1e-30 106.9 0.2 2.2e-30 105.9 0.2 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_pro PF08758.11 KFQ94300.1 - 1.3e-17 63.7 0.0 7.2e-17 61.3 0.0 2.2 2 0 0 2 2 2 1 Cadherin prodomain like Cadherin_3 PF16184.5 KFQ94300.1 - 8.7e-07 28.9 6.9 0.0067 16.4 0.2 4.5 4 0 0 4 4 4 2 Cadherin-like Cadherin_2 PF08266.12 KFQ94300.1 - 6.4e-05 22.7 0.0 2.7 7.9 0.0 3.6 3 0 0 3 3 3 2 Cadherin-like He_PIG PF05345.12 KFQ94300.1 - 0.00012 22.2 7.4 0.027 14.7 0.3 5.0 5 0 0 5 5 5 1 Putative Ig domain Cadherin_4 PF17803.1 KFQ94300.1 - 0.026 15.1 25.8 0.17 12.5 0.8 5.4 6 0 0 6 6 6 0 Bacterial cadherin-like domain Stevor PF17410.2 KFQ94300.1 - 0.034 13.7 0.2 0.055 13.0 0.2 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame EphA2_TM PF14575.6 KFQ94300.1 - 0.051 14.5 0.0 0.12 13.3 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PKD PF00801.20 KFQ94300.1 - 0.077 12.9 0.6 2.8 7.8 0.1 3.5 4 0 0 4 4 4 0 PKD domain DUF5527 PF17665.1 KFQ94300.1 - 0.14 11.7 1.4 0.2 11.2 0.4 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5527) FDF PF09532.10 KFQ94301.1 - 1.5e-24 86.8 8.9 1.5e-24 86.8 8.9 1.7 2 0 0 2 2 2 1 FDF domain LSM14 PF12701.7 KFQ94301.1 - 2.1e-12 46.9 0.0 3.6e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain Proteasome PF00227.26 KFQ94302.1 - 1.6e-60 203.8 0.1 1.9e-60 203.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF5069 PF16798.5 KFQ94302.1 - 0.095 12.9 0.2 0.92 9.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5069) Hormone_3 PF00159.18 KFQ94302.1 - 0.1 12.7 0.5 4.7 7.4 0.1 2.3 2 0 0 2 2 2 0 Pancreatic hormone peptide SSXT PF05030.12 KFQ94303.1 - 9.7e-33 111.6 5.0 2.8e-32 110.1 5.0 1.8 1 0 0 1 1 1 1 SSXT protein (N-terminal region) Elf4 PF07011.11 KFQ94303.1 - 0.032 14.1 1.5 1.4 8.9 0.1 2.5 1 1 1 2 2 2 0 Early Flowering 4 domain GTP1_OBG PF01018.22 KFQ94304.1 - 4e-46 156.4 8.4 5.4e-46 156.0 8.4 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 KFQ94304.1 - 1.3e-24 86.4 0.0 2e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFQ94304.1 - 1.2e-12 47.6 0.0 2.9e-12 46.4 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 KFQ94304.1 - 4.2e-05 23.1 0.0 6.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Dynamin_N PF00350.23 KFQ94304.1 - 0.00093 19.3 0.0 0.26 11.3 0.0 2.2 1 1 1 2 2 2 2 Dynamin family Ras PF00071.22 KFQ94304.1 - 0.017 14.7 0.0 0.036 13.7 0.0 1.6 1 1 0 1 1 1 0 Ras family Gtr1_RagA PF04670.12 KFQ94304.1 - 0.02 14.2 0.0 0.029 13.7 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Roc PF08477.13 KFQ94304.1 - 0.022 14.9 0.0 0.16 12.2 0.0 2.1 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KFQ94304.1 - 0.13 12.8 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter MMR_HSR1_Xtn PF16897.5 KFQ94304.1 - 0.16 12.0 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Oxysterol_BP PF01237.18 KFQ94305.1 - 2.5e-149 497.2 0.1 3e-149 496.9 0.1 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein RPN13_C PF16550.5 KFQ94306.1 - 3.2e-36 123.9 2.4 5.5e-36 123.1 2.4 1.4 1 0 0 1 1 1 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 KFQ94306.1 - 3.7e-33 113.9 0.1 6.5e-33 113.1 0.1 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor ASXH PF13919.6 KFQ94306.1 - 0.0091 16.0 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Asx homology domain GerD PF17898.1 KFQ94306.1 - 0.022 14.7 1.3 0.065 13.2 0.2 2.0 2 0 0 2 2 2 0 Spore germination GerD central core domain Laminin_EGF PF00053.24 KFQ94307.1 - 9.3e-154 499.5 440.0 2.1e-11 43.8 14.7 23.2 20 3 3 23 23 23 22 Laminin EGF domain Laminin_N PF00055.17 KFQ94307.1 - 1e-67 228.2 0.0 1e-67 228.2 0.0 2.7 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_G_2 PF02210.24 KFQ94307.1 - 7.2e-65 217.3 0.0 4e-20 72.7 0.0 5.9 6 0 0 6 6 6 5 Laminin G domain Laminin_G_1 PF00054.23 KFQ94307.1 - 4.6e-54 182.1 0.0 4.6e-18 65.7 0.0 5.4 5 0 0 5 5 5 5 Laminin G domain Laminin_I PF06008.14 KFQ94307.1 - 6.4e-52 176.8 38.7 6.4e-52 176.8 38.7 2.7 2 1 0 2 2 2 1 Laminin Domain I Laminin_B PF00052.18 KFQ94307.1 - 3.8e-38 130.4 0.8 8e-38 129.4 0.1 2.0 2 0 0 2 2 2 1 Laminin B (Domain IV) Laminin_II PF06009.12 KFQ94307.1 - 3.3e-36 124.3 5.0 3.3e-36 124.3 5.0 5.2 2 2 2 5 5 5 2 Laminin Domain II Laminin_G_3 PF13385.6 KFQ94307.1 - 5.9e-15 55.7 0.1 0.00013 22.2 0.0 3.6 3 0 0 3 3 3 3 Concanavalin A-like lectin/glucanases superfamily Cyclin_N PF00134.23 KFQ94308.1 - 6e-09 35.7 0.5 1.1e-08 34.9 0.5 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain HGTP_anticodon PF03129.20 KFQ94308.1 - 0.14 12.3 0.0 0.7 10.1 0.0 2.0 2 0 0 2 2 2 0 Anticodon binding domain CtIP_N PF10482.9 KFQ94309.1 - 2e-54 182.7 19.4 2e-54 182.7 19.4 2.1 2 0 0 2 2 2 1 Tumour-suppressor protein CtIP N-terminal domain Atg14 PF10186.9 KFQ94309.1 - 0.005 16.0 8.0 0.012 14.7 8.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 TSC22 PF01166.18 KFQ94309.1 - 0.14 12.5 10.7 0.65 10.3 1.0 3.6 2 1 1 3 3 3 0 TSC-22/dip/bun family HI0933_like PF03486.14 KFQ94309.1 - 2.2 6.9 4.4 3.6 6.2 4.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Spc24 PF08286.11 KFQ94309.1 - 3 8.1 12.4 4.2 7.7 1.4 3.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF4618 PF15397.6 KFQ94309.1 - 3.2 7.1 17.8 1.8 7.9 3.4 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) bZIP_1 PF00170.21 KFQ94309.1 - 3.4 7.8 19.7 0.42 10.7 1.8 3.6 3 1 1 4 4 4 0 bZIP transcription factor DivIC PF04977.15 KFQ94309.1 - 5.1 6.9 18.5 0.2 11.5 0.6 3.5 3 1 0 3 3 3 0 Septum formation initiator NRBF2 PF08961.10 KFQ94309.1 - 7.5 6.1 20.4 0.17 11.5 4.5 3.2 2 1 1 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator GATA-N PF05349.12 KFQ94310.1 - 5.8e-70 235.2 15.4 7.3e-70 234.9 15.4 1.1 1 0 0 1 1 1 1 GATA-type transcription activator, N-terminal GATA PF00320.27 KFQ94310.1 - 4.1e-29 99.9 16.3 1.6e-15 56.4 5.4 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KFQ94310.1 - 5.6e-05 22.6 9.5 0.027 14.0 3.4 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.18 KFQ94310.1 - 0.011 15.8 1.9 0.25 11.4 0.1 2.2 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf eIF-5_eIF-2B PF01873.17 KFQ94310.1 - 0.029 14.2 5.4 3 7.8 2.4 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 DUF2387 PF09526.10 KFQ94310.1 - 0.17 12.0 5.7 4.9 7.4 0.3 3.0 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) Zn-ribbon_8 PF09723.10 KFQ94310.1 - 0.3 11.2 6.8 2.8 8.1 1.3 2.8 2 1 1 3 3 3 0 Zinc ribbon domain DZR PF12773.7 KFQ94310.1 - 0.39 10.8 8.3 18 5.4 1.6 2.7 1 1 1 2 2 2 0 Double zinc ribbon Auto_anti-p27 PF06677.12 KFQ94310.1 - 0.9 9.7 8.9 0.6 10.3 0.6 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Vps36-NZF-N PF16988.5 KFQ94310.1 - 1.2 8.5 10.4 0.17 11.3 1.4 3.3 1 1 2 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain OrfB_Zn_ribbon PF07282.11 KFQ94310.1 - 1.3 9.0 8.0 3.1 7.8 0.4 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Prim_Zn_Ribbon PF08273.12 KFQ94310.1 - 2.7 8.4 11.2 0.28 11.5 2.2 2.7 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase OATP PF03137.20 KFQ94311.1 - 1.8e-183 610.7 17.0 2.3e-183 610.4 17.0 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFQ94311.1 - 2e-15 56.6 26.9 2e-15 56.6 26.9 2.9 2 2 0 2 2 2 1 Major Facilitator Superfamily Kazal_2 PF07648.15 KFQ94311.1 - 4.6e-09 36.2 11.2 1.4e-08 34.7 11.2 1.9 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFQ94311.1 - 0.63 10.1 9.2 2 8.5 9.2 1.9 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain 7tm_1 PF00001.21 KFQ94312.1 - 6.5e-12 45.3 12.5 9.5e-12 44.8 12.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Eaf7 PF07904.13 KFQ94313.1 - 1e-07 32.3 4.2 3.6e-07 30.5 4.2 2.3 1 1 0 1 1 1 1 Chromatin modification-related protein EAF7 Asp-B-Hydro_N PF05279.11 KFQ94313.1 - 0.023 14.8 4.6 0.027 14.6 4.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RAP1 PF07218.11 KFQ94313.1 - 0.7 8.1 4.6 0.87 7.8 4.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) OGFr_N PF04664.13 KFQ94314.1 - 1.4e-104 348.1 8.6 2e-104 347.7 8.6 1.1 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region Collagen PF01391.18 KFQ94315.1 - 4.1e-18 64.9 59.9 1.6e-07 31.0 41.2 2.4 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) HLH PF00010.26 KFQ94316.1 - 4.2e-10 39.4 0.4 1.5e-09 37.6 0.1 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain CLTH PF10607.9 KFQ94317.1 - 2.6e-34 118.3 5.2 3.3e-34 117.9 5.2 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KFQ94317.1 - 1.2e-12 47.3 0.5 4.7e-11 42.2 0.1 2.7 2 0 0 2 2 2 1 LisH MFS_1 PF07690.16 KFQ94318.1 - 9.7e-46 156.3 27.1 9.7e-46 156.3 27.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RAG1 PF12940.7 KFQ94320.1 - 0 1251.5 0.8 0 1251.0 0.8 1.1 1 0 0 1 1 1 1 Recombination-activation protein 1 (RAG1), recombinase RAG1_imp_bd PF12560.8 KFQ94320.1 - 4e-117 390.8 15.5 4e-117 390.8 15.5 2.1 2 0 0 2 2 2 1 RAG1 importin binding zf-RAG1 PF10426.9 KFQ94320.1 - 3.9e-18 65.3 10.3 4.2e-17 62.0 1.8 2.7 2 0 0 2 2 2 2 Recombination-activating protein 1 zinc-finger domain zf-C3HC4 PF00097.25 KFQ94320.1 - 2e-06 27.6 15.0 2e-06 27.6 15.0 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFQ94320.1 - 9.5e-05 22.2 14.2 9.5e-05 22.2 14.2 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KFQ94320.1 - 0.00021 21.1 8.4 0.00021 21.1 8.4 2.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KFQ94320.1 - 0.008 16.3 13.5 0.008 16.3 13.5 3.2 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING RAG2 PF03089.14 KFQ94321.1 - 4.3e-188 624.3 0.1 5.5e-188 624.0 0.1 1.1 1 0 0 1 1 1 1 Recombination activating protein 2 RAG2_PHD PF13341.6 KFQ94321.1 - 2e-47 159.1 2.2 4.3e-47 158.1 2.2 1.6 1 0 0 1 1 1 1 RAG2 PHD domain Kelch_3 PF13415.6 KFQ94321.1 - 5.5e-07 29.7 0.0 0.024 14.9 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KFQ94321.1 - 1.1e-05 25.3 0.4 0.94 9.5 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 KFQ94321.1 - 0.00027 20.9 0.8 9.6 6.3 0.0 4.8 5 0 0 5 5 5 1 Galactose oxidase, central domain PHD PF00628.29 KFQ94321.1 - 0.0022 17.8 0.1 0.012 15.5 0.1 2.3 1 0 0 1 1 1 1 PHD-finger Kelch_6 PF13964.6 KFQ94321.1 - 0.11 12.8 0.0 2.5 8.5 0.0 3.2 4 0 0 4 4 4 0 Kelch motif Kelch_1 PF01344.25 KFQ94321.1 - 0.17 11.5 0.3 1.3 8.6 0.0 2.6 3 0 0 3 3 3 0 Kelch motif DUF5567 PF17722.1 KFQ94322.1 - 2.9e-59 200.8 1.7 3.2e-59 200.7 1.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5567) PDEase_I PF00233.19 KFQ94324.1 - 5.6e-75 252.1 1.0 7.2e-75 251.8 1.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Meiosis_expr PF15163.6 KFQ94324.1 - 0.15 12.7 0.0 0.35 11.5 0.0 1.6 1 0 0 1 1 1 0 Meiosis-expressed Mito_fiss_reg PF05308.11 KFQ94325.1 - 4.9e-81 272.5 3.9 7.2e-81 271.9 3.9 1.2 1 0 0 1 1 1 1 Mitochondrial fission regulator PRIMA1 PF16101.5 KFQ94325.1 - 0.49 10.4 8.9 1 9.4 8.9 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 FlxA PF14282.6 KFQ94325.1 - 2 8.4 8.4 0.058 13.4 1.5 2.0 2 0 0 2 2 2 0 FlxA-like protein Arm PF00514.23 KFQ94326.1 - 2.7e-05 24.0 0.0 6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat HMA PF00403.26 KFQ94326.1 - 0.0017 18.7 0.1 0.0032 17.9 0.1 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain RVT_1 PF00078.27 KFQ94327.1 - 0.0038 16.8 0.0 0.0082 15.7 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) p450 PF00067.22 KFQ94328.1 - 8.6e-51 173.1 0.3 1.3e-50 172.6 0.3 1.2 1 0 0 1 1 1 1 Cytochrome P450 MIOX PF05153.15 KFQ94330.1 - 4.2e-87 291.8 1.9 4.7e-87 291.7 1.9 1.0 1 0 0 1 1 1 1 Myo-inositol oxygenase LMF1 PF06762.14 KFQ94331.1 - 4.1e-93 312.9 16.3 4.9e-93 312.7 16.3 1.0 1 0 0 1 1 1 1 Lipase maturation factor TMEM191C PF15194.6 KFQ94331.1 - 2 8.6 6.5 2.5 8.3 2.8 2.3 2 0 0 2 2 2 0 TMEM191C family CNDH2_C PF16858.5 KFQ94332.1 - 5.6e-24 85.5 0.1 3.6e-23 82.9 0.1 1.8 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term Carn_acyltransf PF00755.20 KFQ94333.1 - 6.1e-105 352.1 2.0 4.8e-56 190.6 0.1 3.0 3 0 0 3 3 3 3 Choline/Carnitine o-acyltransferase CPT_N PF16484.5 KFQ94333.1 - 1.6e-22 79.2 0.2 3.3e-22 78.2 0.2 1.6 1 0 0 1 1 1 1 Carnitine O-palmitoyltransferase N-terminus Fer4_22 PF17179.4 KFQ94333.1 - 0.2 12.5 0.4 4.1 8.3 0.8 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Choline_kinase PF01633.20 KFQ94334.1 - 1.7e-53 181.4 0.1 2.5e-53 180.8 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KFQ94334.1 - 1.6e-09 38.0 0.0 2.3e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFQ94334.1 - 1.7e-05 24.3 0.1 3.3e-05 23.4 0.1 1.5 1 1 0 1 1 1 1 Ecdysteroid kinase Pkinase_fungal PF17667.1 KFQ94334.1 - 0.017 14.0 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PID PF00640.23 KFQ94335.1 - 1.1e-17 64.3 3.1 2.1e-17 63.4 2.2 1.7 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) SH3_9 PF14604.6 KFQ94335.1 - 9.9e-16 57.3 0.2 1.8e-15 56.5 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFQ94335.1 - 5.8e-08 32.2 0.0 9.8e-08 31.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFQ94335.1 - 0.00064 19.4 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PDZ_6 PF17820.1 KFQ94336.1 - 1.8e-09 37.3 0.2 4e-09 36.2 0.2 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFQ94336.1 - 2.8e-07 30.8 0.0 1.2e-06 28.7 0.0 2.2 2 1 0 2 2 2 1 PDZ domain 2C_adapt PF08793.10 KFQ94336.1 - 0.02 15.0 0.1 0.39 10.9 0.0 2.5 2 0 0 2 2 2 0 2-cysteine adaptor domain Ank_2 PF12796.7 KFQ94337.1 - 3.3e-16 59.7 4.3 3.8e-08 33.8 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ94337.1 - 2.2e-15 56.8 4.7 4.7e-06 27.0 0.4 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFQ94337.1 - 2.6e-15 56.3 3.3 1e-07 32.1 0.2 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFQ94337.1 - 9.4e-13 48.0 8.7 0.022 15.2 0.1 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KFQ94337.1 - 2.9e-12 45.6 6.2 0.0038 17.6 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat FERM_f0 PF16511.5 KFQ94338.1 - 0.00023 21.4 0.0 0.0011 19.3 0.0 1.9 2 0 0 2 2 2 1 N-terminal or F0 domain of Talin-head FERM Membr_traf_MHD PF10540.9 KFQ94339.1 - 5e-55 185.8 2.5 9.3e-55 184.9 2.5 1.5 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KFQ94339.1 - 5.6e-14 52.3 0.0 2.4e-13 50.3 0.0 2.0 2 0 0 2 2 2 1 C2 domain KH_1 PF00013.29 KFQ94340.1 - 5.6e-22 77.3 1.5 2.1e-14 53.1 0.1 2.7 3 0 0 3 3 3 2 KH domain zf-C3HC4_3 PF13920.6 KFQ94340.1 - 1.8e-10 40.5 10.2 2.7e-10 39.9 10.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ94340.1 - 1.9e-05 24.9 11.4 3.3e-05 24.1 11.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFQ94340.1 - 0.00085 19.1 10.9 0.0015 18.4 10.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFQ94340.1 - 0.0029 17.4 11.2 0.0055 16.5 11.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFQ94340.1 - 0.079 12.9 10.7 0.15 12.1 10.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain KH_2 PF07650.17 KFQ94340.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 KH domain zf-RING_UBOX PF13445.6 KFQ94340.1 - 0.17 11.9 7.1 0.39 10.8 7.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFQ94340.1 - 1.4 9.1 9.6 4 7.7 9.6 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KFQ94340.1 - 3.2 7.6 9.4 7.3 6.5 9.4 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain MBD_C PF14048.6 KFQ94341.1 - 6.5e-36 122.9 0.4 1.2e-35 122.1 0.1 1.6 2 0 0 2 2 2 1 C-terminal domain of methyl-CpG binding protein 2 and 3 MBDa PF16564.5 KFQ94341.1 - 6.7e-31 106.3 0.8 1.4e-30 105.3 0.8 1.5 1 0 0 1 1 1 1 p55-binding region of Methyl-CpG-binding domain proteins MBD MBD PF01429.19 KFQ94341.1 - 1.9e-08 33.9 0.2 0.00024 20.7 0.0 2.3 2 0 0 2 2 2 2 Methyl-CpG binding domain RasGAP PF00616.19 KFQ94341.1 - 0.0022 17.7 0.0 0.0036 17.0 0.0 1.4 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase NUMOD1 PF07453.13 KFQ94341.1 - 0.19 12.0 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 NUMOD1 domain RNA_pol_3_Rpc31 PF11705.8 KFQ94341.1 - 0.92 9.7 10.2 0.24 11.6 7.3 1.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 UCR_6-4kD PF08997.10 KFQ94342.1 - 2.1e-18 66.0 2.3 2.3e-18 65.9 2.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein QCR10 PF09796.9 KFQ94342.1 - 4.8e-05 23.3 2.8 0.00039 20.4 2.8 1.9 1 1 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Lamprin PF06403.11 KFQ94343.1 - 0.00012 22.1 2.8 0.00012 22.1 2.8 1.1 1 0 0 1 1 1 1 Lamprin Chorion_1 PF01723.16 KFQ94343.1 - 0.042 13.8 12.4 0.093 12.7 12.4 1.6 1 1 0 1 1 1 0 Chorion protein Lem_TRP PF08262.11 KFQ94343.1 - 7.8 6.8 15.8 19 5.6 1.4 5.1 2 1 5 7 7 7 0 Leucophaea maderae tachykinin-related peptide CUT PF02376.15 KFQ94344.1 - 9.6e-32 109.0 0.5 1.6e-31 108.3 0.5 1.3 1 0 0 1 1 1 1 CUT domain Homeodomain PF00046.29 KFQ94344.1 - 1.3e-09 37.7 1.4 2.5e-09 36.8 1.4 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ94344.1 - 0.0036 17.2 0.0 0.0094 15.8 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain PhoLip_ATPase_C PF16212.5 KFQ94345.1 - 1.2e-65 221.8 18.7 1.2e-65 221.8 18.7 2.8 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFQ94345.1 - 1.9e-20 72.3 6.3 5.7e-20 70.8 6.3 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KFQ94345.1 - 7.6e-15 54.8 0.6 1.3e-12 47.6 0.0 3.2 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFQ94345.1 - 1.3e-10 42.0 2.4 0.0005 20.4 0.1 3.4 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFQ94345.1 - 5.9e-07 29.2 2.2 7.4e-06 25.6 0.0 3.0 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFQ94345.1 - 0.0013 18.5 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase EloA-BP1 PF15870.5 KFQ94346.1 - 2.6e-73 245.7 0.2 2.6e-73 245.7 0.2 4.0 2 1 1 3 3 3 1 ElonginA binding-protein 1 RNase_T PF00929.24 KFQ94346.1 - 2.8e-07 31.2 0.2 1.1e-05 26.1 0.1 2.6 2 0 0 2 2 2 1 Exonuclease Hydrolase_4 PF12146.8 KFQ94347.1 - 0.00038 19.8 0.0 0.0007 18.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFQ94347.1 - 0.0008 19.1 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFQ94347.1 - 0.016 14.7 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family FSH1 PF03959.13 KFQ94347.1 - 0.021 14.5 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) UPF0227 PF05728.12 KFQ94347.1 - 0.025 14.5 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) zf-A20 PF01754.16 KFQ94348.1 - 8.1e-13 48.1 6.9 2.5e-12 46.5 6.9 1.9 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.16 KFQ94348.1 - 8.5e-09 35.4 7.0 8.5e-09 35.4 7.0 2.2 2 0 0 2 2 2 1 AN1-like Zinc finger MARCKS PF02063.17 KFQ94348.1 - 0.015 15.3 3.7 0.024 14.6 3.7 1.2 1 0 0 1 1 1 0 MARCKS family TerY_C PF15616.6 KFQ94348.1 - 0.038 14.1 0.8 0.038 14.1 0.8 1.9 2 0 0 2 2 2 0 TerY-C metal binding domain zf-C4 PF00105.18 KFQ94349.1 - 2.2e-33 114.5 13.6 4.3e-33 113.6 13.6 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) SCAMP PF04144.13 KFQ94350.1 - 5.2e-67 225.5 23.4 5.9e-67 225.3 23.4 1.0 1 0 0 1 1 1 1 SCAMP family ATP-gua_Ptrans PF00217.19 KFQ94350.1 - 0.19 11.2 0.0 0.25 10.8 0.0 1.1 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, C-terminal catalytic domain DUF4051 PF13260.6 KFQ94350.1 - 0.35 10.6 0.0 0.35 10.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) CK1gamma_C PF12605.8 KFQ94351.1 - 9.5e-25 87.7 3.4 1.8e-24 86.8 3.4 1.5 1 0 0 1 1 1 1 Casein kinase 1 gamma C terminal Pkinase PF00069.25 KFQ94351.1 - 4.5e-23 81.9 0.0 6.7e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ94351.1 - 3.4e-12 46.2 0.0 4.9e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFQ94351.1 - 7.5e-08 31.5 0.1 1e-07 31.1 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase PHR PF08005.12 KFQ94352.1 - 5e-54 183.1 1.1 7.9e-54 182.4 1.1 1.3 1 0 0 1 1 1 1 PHR domain BTB PF00651.31 KFQ94352.1 - 6.8e-22 77.8 0.4 5.8e-20 71.6 0.0 2.8 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.15 KFQ94352.1 - 2.8e-10 40.2 0.9 7e-09 35.7 0.2 3.0 1 1 2 3 3 3 1 BTB And C-terminal Kelch DUF4082 PF13313.6 KFQ94352.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) Pkinase PF00069.25 KFQ94353.1 - 1.2e-47 162.5 0.0 1.4e-43 149.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ94353.1 - 1.1e-16 60.9 0.0 2.3e-15 56.6 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KFQ94353.1 - 0.00023 20.6 0.1 0.00044 19.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFQ94353.1 - 0.0054 15.6 0.0 0.0089 14.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase zf-RRN7 PF11781.8 KFQ94353.1 - 0.0097 15.6 0.1 0.023 14.4 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 FTA2 PF13095.6 KFQ94353.1 - 0.061 12.9 0.0 3.2 7.3 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFQ94353.1 - 0.12 12.3 0.5 0.2 11.6 0.1 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Mob1_phocein PF03637.17 KFQ94354.1 - 8.3e-84 279.8 0.3 9.4e-84 279.6 0.3 1.0 1 0 0 1 1 1 1 Mob1/phocein family DOT1 PF08123.13 KFQ94355.1 - 5e-83 277.7 0.4 1.4e-82 276.2 0.0 1.9 2 0 0 2 2 2 1 Histone methylation protein DOT1 DUF2000 PF09391.10 KFQ94355.1 - 0.69 9.8 2.4 20 5.1 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2000) HALZ PF02183.18 KFQ94355.1 - 2.7 8.3 15.5 6.9 7.0 10.0 3.4 2 1 1 3 3 3 0 Homeobox associated leucine zipper SF3A2 PF16835.5 KFQ94356.1 - 2.9e-40 136.5 0.2 4.9e-40 135.8 0.2 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KFQ94356.1 - 3.3e-07 30.5 2.0 3.3e-07 30.5 2.0 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 KFQ94356.1 - 0.004 17.1 0.1 0.0066 16.4 0.1 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 KFQ94356.1 - 0.051 13.1 3.2 0.094 12.3 3.2 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like LPD24 PF18839.1 KFQ94356.1 - 0.22 11.8 0.7 28 5.0 0.0 2.7 3 0 0 3 3 3 0 Large polyvalent protein associated domain 24 zf-C2H2_jaz PF12171.8 KFQ94356.1 - 4.9 7.6 6.7 9.9 6.6 5.1 2.3 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding AMH_N PF04709.12 KFQ94358.1 - 1.5e-74 251.3 3.3 1.3e-58 198.8 2.7 2.1 1 1 1 2 2 2 2 Anti-Mullerian hormone, N terminal region TGF_beta PF00019.20 KFQ94358.1 - 1.6e-17 64.4 0.6 2.5e-17 63.7 0.6 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain JSRP PF15312.6 KFQ94359.1 - 2.3e-10 40.2 1.3 2.3e-10 40.2 1.3 2.3 2 2 0 2 2 2 1 Junctional sarcoplasmic reticulum protein LRR_8 PF13855.6 KFQ94361.1 - 4.6e-55 183.2 63.3 6e-13 48.3 4.1 5.9 1 1 7 8 8 8 8 Leucine rich repeat LRR_5 PF13306.6 KFQ94361.1 - 2e-27 95.7 1.0 5.9e-12 45.7 0.1 2.5 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFQ94361.1 - 5.2e-17 61.7 28.0 8.9e-06 26.0 2.0 6.8 4 2 1 7 7 7 6 Leucine Rich repeats (2 copies) I-set PF07679.16 KFQ94361.1 - 1.9e-16 59.9 0.0 3e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ94361.1 - 1.1e-13 51.5 0.0 2.4e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFQ94361.1 - 6.3e-10 39.1 0.1 1.4e-09 38.0 0.0 1.6 2 0 0 2 2 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFQ94361.1 - 2e-07 31.3 0.0 3.8e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.33 KFQ94361.1 - 1e-05 25.4 30.5 0.38 11.5 0.0 10.5 11 1 0 11 11 10 2 Leucine Rich Repeat LRRNT PF01462.18 KFQ94361.1 - 0.0038 16.8 3.5 0.0038 16.8 3.5 3.0 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain V-set PF07686.17 KFQ94361.1 - 0.0042 17.2 0.1 0.16 12.2 0.0 2.6 2 1 0 2 2 2 1 Immunoglobulin V-set domain LRR_9 PF14580.6 KFQ94361.1 - 0.014 14.9 12.7 0.29 10.6 5.4 3.0 1 1 2 3 3 3 0 Leucine-rich repeat Ig_6 PF18452.1 KFQ94361.1 - 0.021 14.4 0.0 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain LRRCT PF01463.24 KFQ94361.1 - 0.023 15.2 2.2 0.26 11.9 0.1 3.9 3 1 1 4 4 4 0 Leucine rich repeat C-terminal domain LRR_6 PF13516.6 KFQ94361.1 - 0.15 12.2 26.7 1.5 9.0 0.0 8.4 10 0 0 10 10 10 0 Leucine Rich repeat XK-related PF09815.9 KFQ94363.1 - 7.4e-91 304.7 30.5 8.6e-91 304.5 30.5 1.0 1 0 0 1 1 1 1 XK-related protein BLACT_WH PF17778.1 KFQ94364.1 - 7.8e-18 64.2 0.0 2.6e-17 62.5 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 KFQ94364.1 - 1.5e-16 61.0 0.2 2e-16 60.6 0.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFQ94364.1 - 0.00023 20.7 0.1 0.0004 20.0 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain HTH_24 PF13412.6 KFQ94364.1 - 0.044 13.4 0.2 8.1 6.1 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TRAM_LAG1_CLN8 PF03798.16 KFQ94365.1 - 3.6e-26 92.1 18.8 3.6e-26 92.1 18.8 1.4 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KFQ94365.1 - 2.1e-22 78.5 2.6 2.6e-22 78.3 0.7 2.2 2 0 0 2 2 2 1 TRAM1-like protein DUF3382 PF11862.8 KFQ94365.1 - 0.037 14.3 0.1 0.13 12.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) DUF3671 PF12420.8 KFQ94365.1 - 1.4 9.0 10.5 0.18 11.9 3.5 2.8 2 1 1 3 3 3 0 Protein of unknown function NCOA_u2 PF16665.5 KFQ94366.1 - 3.7e-38 130.5 16.6 3.7e-38 130.5 16.6 4.7 5 0 0 5 5 5 1 Unstructured region on nuclear receptor coactivator protein PAS_11 PF14598.6 KFQ94366.1 - 2.7e-33 114.5 5.5 3.6e-31 107.6 0.7 2.8 3 0 0 3 3 3 2 PAS domain DUF4927 PF16279.5 KFQ94366.1 - 3.4e-30 104.9 4.5 3.4e-30 104.9 4.5 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4927) DUF1518 PF07469.12 KFQ94366.1 - 1.9e-25 89.0 15.7 1.9e-25 89.0 15.7 4.8 4 1 0 4 4 4 1 Domain of unknown function (DUF1518) Nuc_rec_co-act PF08815.10 KFQ94366.1 - 4e-24 84.2 0.2 1e-23 82.9 0.2 1.7 1 0 0 1 1 1 1 Nuclear receptor coactivator SRC-1 PF08832.10 KFQ94366.1 - 7.4e-21 75.0 4.2 7.4e-21 75.0 4.2 4.0 3 1 0 3 3 3 1 Steroid receptor coactivator PAS PF00989.25 KFQ94366.1 - 3.4e-07 30.3 2.5 7.2e-07 29.2 0.0 2.6 3 0 0 3 3 3 1 PAS fold PAS_3 PF08447.12 KFQ94366.1 - 8.6e-07 29.2 0.0 0.065 13.5 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KFQ94366.1 - 1.9e-05 24.9 0.0 7.6e-05 22.9 0.0 2.1 1 0 0 1 1 1 1 PAS domain HLH PF00010.26 KFQ94366.1 - 0.0064 16.4 0.6 0.014 15.4 0.6 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain zf-H2C2_2 PF13465.6 KFQ94367.1 - 3e-21 74.8 53.8 2.9e-09 36.9 0.7 6.7 7 0 0 7 7 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ94367.1 - 2.1e-19 68.8 56.5 3.5e-07 30.3 3.2 6.6 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ94367.1 - 1.2e-17 63.1 53.3 0.00015 22.3 3.1 6.5 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ94367.1 - 3.6e-08 33.5 31.0 0.0039 17.4 0.6 6.2 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFQ94367.1 - 7.8e-08 32.1 41.2 0.00026 20.9 3.5 7.0 6 1 0 6 6 6 5 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFQ94367.1 - 1.9e-05 24.4 27.0 0.072 13.0 2.8 6.5 6 0 0 6 6 6 3 zinc-finger of a C2HC-type SET PF00856.28 KFQ94367.1 - 3.8e-05 24.1 0.1 0.0016 18.9 0.1 2.4 1 1 0 1 1 1 1 SET domain zf_UBZ PF18439.1 KFQ94367.1 - 0.0013 18.3 26.4 0.68 9.6 0.2 6.3 6 0 0 6 6 6 3 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 KFQ94367.1 - 0.0028 18.0 33.1 0.31 11.5 2.5 6.3 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFQ94367.1 - 0.0075 16.0 2.8 0.0075 16.0 2.8 6.1 7 0 0 7 7 7 2 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KFQ94367.1 - 0.011 16.0 34.5 0.47 10.8 2.1 5.6 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) YhfH PF14149.6 KFQ94367.1 - 0.014 15.4 11.9 3.3 7.7 1.2 4.6 4 0 0 4 4 4 0 YhfH-like protein zf-Di19 PF05605.12 KFQ94367.1 - 0.022 15.0 34.5 0.35 11.2 5.5 3.8 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_15 PF17032.5 KFQ94367.1 - 0.051 14.3 26.0 0.083 13.7 1.3 3.6 2 1 2 4 4 3 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 KFQ94367.1 - 0.086 13.0 25.8 1.1 9.4 1.6 4.8 3 2 2 5 5 5 0 Zinc ribbon domain PyrI_C PF02748.15 KFQ94367.1 - 0.74 9.8 24.7 0.33 10.9 0.2 5.6 5 1 1 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain HypA PF01155.19 KFQ94367.1 - 1.4 9.0 19.3 8.7 6.4 3.0 3.8 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2256 PF10013.9 KFQ94367.1 - 2.4 8.4 21.4 14 5.9 0.1 6.1 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) HNH_5 PF14279.6 KFQ94367.1 - 3 7.8 20.5 6 6.8 0.1 5.4 5 1 0 5 5 5 0 HNH endonuclease zf-CHCC PF10276.9 KFQ94367.1 - 9.2 6.4 17.7 9.3 6.4 0.0 5.0 5 0 0 5 5 5 0 Zinc-finger domain DUF3740 PF12548.8 KFQ94368.1 - 4.8e-59 199.0 23.8 3.1e-54 183.4 2.8 2.8 3 0 0 3 3 3 2 Sulfatase protein Sulfatase PF00884.23 KFQ94368.1 - 3.5e-53 181.0 1.8 3.8e-53 180.9 0.5 1.7 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KFQ94368.1 - 0.0001 22.1 3.5 0.0023 17.6 1.8 2.8 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF5586 PF17824.1 KFQ94370.1 - 5.9e-196 651.4 11.6 6.7e-196 651.2 11.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5586) DEAD_assoc PF08494.11 KFQ94370.1 - 0.089 12.6 0.2 0.15 11.8 0.2 1.3 1 0 0 1 1 1 0 DEAD/H associated Calpain_inhib PF00748.19 KFQ94370.1 - 0.47 11.0 7.2 0.54 10.8 2.6 2.5 2 0 0 2 2 2 0 Calpain inhibitor Peptidase_M14 PF00246.24 KFQ94371.1 - 3.6e-89 299.4 0.1 4.4e-89 299.1 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KFQ94371.1 - 8.6e-11 42.1 1.1 1.1e-10 41.8 0.1 1.7 2 0 0 2 2 2 1 Carboxypeptidase activation peptide Pro_racemase PF05544.11 KFQ94372.1 - 2.5e-66 223.9 0.0 2.9e-66 223.8 0.0 1.0 1 0 0 1 1 1 1 Proline racemase JAMP PF05571.12 KFQ94373.1 - 5.1e-115 384.1 10.4 5.8e-115 383.9 10.4 1.0 1 0 0 1 1 1 1 JNK1/MAPK8-associated membrane protein GTPase_binding PF09027.10 KFQ94373.1 - 0.068 13.2 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 GTPase binding Calici_PP_N PF08405.11 KFQ94373.1 - 6.6 5.4 5.8 3.7 6.3 0.2 2.3 2 1 1 3 3 3 0 Viral polyprotein N-terminal Reticulon PF02453.17 KFQ94374.1 - 1.7e-46 158.0 7.5 2.4e-46 157.5 7.5 1.2 1 0 0 1 1 1 1 Reticulon DUF4736 PF15883.5 KFQ94374.1 - 0.049 13.3 0.1 0.049 13.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) Pecanex_C PF05041.15 KFQ94375.1 - 1.3e-25 90.3 0.0 2.2e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Pecanex protein (C-terminus) TSP_C PF05735.12 KFQ94375.1 - 0.19 11.7 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Thrombospondin C-terminal region YoqO PF14037.6 KFQ94375.1 - 0.38 11.3 6.2 14 6.2 0.1 3.4 3 0 0 3 3 3 0 YoqO-like protein adh_short PF00106.25 KFQ94376.1 - 1.4e-52 178.0 0.0 1.7e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFQ94376.1 - 1.9e-31 109.4 0.0 2.3e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFQ94376.1 - 3e-12 46.8 0.1 4.3e-12 46.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFQ94376.1 - 0.049 13.1 0.1 0.067 12.6 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PP2C PF00481.21 KFQ94377.1 - 9.4e-88 294.2 0.0 1.2e-87 293.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.13 KFQ94377.1 - 1.2e-32 112.2 0.1 2.3e-32 111.3 0.1 1.5 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain S6OS1 PF15676.5 KFQ94378.1 - 8.7e-238 790.4 37.6 9.7e-238 790.2 37.6 1.0 1 0 0 1 1 1 1 Six6 opposite strand transcript 1 family Y_phosphatase3 PF13350.6 KFQ94378.1 - 0.049 13.6 2.9 0.043 13.8 1.2 1.7 1 1 0 1 1 1 0 Tyrosine phosphatase family Fib_alpha PF08702.10 KFQ94378.1 - 0.5 10.5 27.9 1.5 9.0 0.5 3.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family WXG100 PF06013.12 KFQ94378.1 - 0.93 9.8 11.5 0.15 12.3 1.6 3.5 2 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF4201 PF13870.6 KFQ94378.1 - 1.5 8.5 31.6 0.068 12.9 18.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF3452 PF11934.8 KFQ94378.1 - 4.9 6.7 13.3 4.2 6.9 2.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) SIX1_SD PF16878.5 KFQ94379.1 - 2.4e-48 163.3 0.0 2.8e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator, SIX1, N-terminal SD domain SIX1_SD PF16878.5 KFQ94380.1 - 5.2e-47 158.9 0.1 4.7e-45 152.7 0.0 2.2 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 KFQ94380.1 - 1.5e-14 53.6 1.5 3.9e-14 52.2 1.5 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ94380.1 - 6.8e-10 38.7 0.7 1.3e-09 37.8 0.7 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 KFQ94380.1 - 0.031 13.7 0.0 0.082 12.4 0.0 1.7 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez InPase PF18823.1 KFQ94380.1 - 0.18 11.5 0.8 0.27 10.9 0.8 1.2 1 0 0 1 1 1 0 Inorganic Pyrophosphatase MAT1 PF06391.13 KFQ94381.1 - 1.4e-64 217.7 20.1 1.6e-64 217.5 20.1 1.0 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 Met_10 PF02475.16 KFQ94382.1 - 2.7e-66 223.1 0.0 4e-66 222.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_15 PF09445.10 KFQ94382.1 - 0.00013 21.6 0.0 0.00038 20.1 0.0 1.8 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase MethyltransfD12 PF02086.15 KFQ94382.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase TRM PF02005.16 KFQ94382.1 - 0.0029 16.8 0.0 0.0054 15.9 0.0 1.4 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase tRNA_U5-meth_tr PF05958.11 KFQ94382.1 - 0.0048 15.9 0.0 0.015 14.3 0.0 1.7 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase PrmA PF06325.13 KFQ94382.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Aa_trans PF01490.18 KFQ94383.1 - 8e-74 248.8 38.9 9.9e-74 248.5 38.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein C2 PF00168.30 KFQ94384.1 - 7.3e-14 51.9 0.0 8.5e-14 51.7 0.0 1.0 1 0 0 1 1 1 1 C2 domain Tox-REase-5 PF15648.6 KFQ94384.1 - 0.092 13.3 0.0 0.11 13.0 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 5 BclA_C PF18573.1 KFQ94384.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 BclA C-terminal domain HLH PF00010.26 KFQ94385.1 - 5.7e-05 23.0 0.6 6.3e-05 22.8 0.6 1.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3453 PF11935.8 KFQ94386.1 - 7.3e-60 202.4 0.6 9.7e-59 198.7 0.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Symplekin_C PF12295.8 KFQ94386.1 - 2.9e-20 73.1 2.1 7.7e-20 71.8 0.0 2.7 3 0 0 3 3 3 1 Symplekin tight junction protein C terminal Cnd1 PF12717.7 KFQ94386.1 - 0.0059 16.7 1.7 0.37 10.8 0.3 2.6 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFQ94386.1 - 0.0087 16.2 0.0 16 6.1 0.0 3.6 2 0 0 2 2 2 2 HEAT repeat Adaptin_N PF01602.20 KFQ94386.1 - 0.052 12.1 3.3 0.64 8.5 0.2 3.1 4 0 0 4 4 4 0 Adaptin N terminal region Peptidase_M3 PF01432.20 KFQ94387.1 - 4.5e-118 395.4 1.8 6.5e-110 368.5 1.8 2.3 2 0 0 2 2 2 2 Peptidase family M3 Transthyretin PF00576.21 KFQ94387.1 - 0.028 15.1 0.6 1.8 9.3 0.0 3.0 3 0 0 3 3 3 0 HIUase/Transthyretin family TPR_11 PF13414.6 KFQ94388.1 - 1.3e-15 56.7 3.3 4.5e-07 29.5 0.2 2.6 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.28 KFQ94388.1 - 1.5e-14 53.1 2.6 1.2e-06 28.1 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ94388.1 - 5.3e-13 48.0 1.2 4.8e-06 26.3 0.1 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ94388.1 - 2.4e-10 39.8 0.4 0.0017 18.4 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ94388.1 - 1.3e-07 31.1 0.0 0.0037 17.2 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ94388.1 - 1.7e-05 24.9 2.8 0.0013 19.0 0.5 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat SGTA_dimer PF16546.5 KFQ94388.1 - 3.3e-05 23.6 0.3 0.0051 16.6 0.0 3.0 3 0 0 3 3 3 1 Homodimerisation domain of SGTA TPR_14 PF13428.6 KFQ94388.1 - 7.7e-05 23.2 0.0 0.78 10.7 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TOM20_plant PF06552.12 KFQ94388.1 - 0.00022 21.0 0.5 0.093 12.5 0.1 2.5 2 0 0 2 2 2 1 Plant specific mitochondrial import receptor subunit TOM20 MIT PF04212.18 KFQ94388.1 - 0.00032 20.7 3.0 0.6 10.2 0.1 3.3 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 KFQ94388.1 - 0.0012 19.4 0.0 1.9 9.2 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ94388.1 - 0.0014 18.9 0.1 0.43 10.9 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ94388.1 - 0.0053 17.2 0.7 4.3 7.9 0.0 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 KFQ94388.1 - 0.017 14.6 0.0 0.58 9.7 0.1 2.4 2 0 0 2 2 2 0 SHNi-TPR XPC-binding PF09280.11 KFQ94388.1 - 0.019 14.7 10.7 0.22 11.3 3.2 2.4 2 0 0 2 2 2 0 XPC-binding domain TPR_6 PF13174.6 KFQ94388.1 - 0.028 15.1 0.0 4.5 8.1 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat GerD PF17898.1 KFQ94388.1 - 0.035 14.1 0.2 0.46 10.5 0.1 2.3 2 0 0 2 2 2 0 Spore germination GerD central core domain Fucokinase PF07959.12 KFQ94388.1 - 0.055 12.4 0.0 0.073 12.0 0.0 1.1 1 0 0 1 1 1 0 L-fucokinase DUF627 PF04781.12 KFQ94388.1 - 0.11 12.6 0.2 0.39 10.7 0.0 2.0 2 1 0 2 2 1 0 Protein of unknown function (DUF627) TPR_9 PF13371.6 KFQ94388.1 - 0.14 12.3 0.0 11 6.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFQ94388.1 - 0.19 11.8 3.9 1.7 8.8 0.1 2.8 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat STI1 PF17830.1 KFQ94388.1 - 1.8 8.6 8.3 0.22 11.5 2.2 2.3 2 0 0 2 2 2 0 STI1 domain DUF974 PF06159.13 KFQ94389.1 - 5.5e-85 285.1 0.7 7.9e-85 284.6 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Transglut_C PF00927.22 KFQ94389.1 - 0.0015 18.7 0.3 0.028 14.6 0.0 2.9 2 1 1 3 3 3 1 Transglutaminase family, C-terminal ig like domain Trs65 PF12735.7 KFQ94389.1 - 0.0031 17.0 0.0 3 7.2 0.0 3.2 2 1 1 3 3 3 2 TRAPP trafficking subunit Trs65 APOBEC3 PF18771.1 KFQ94390.1 - 0.046 13.8 0.0 0.17 12.0 0.0 1.8 1 1 0 1 1 1 0 APOBEC3 Arf PF00025.21 KFQ94391.1 - 4.7e-71 237.8 0.5 1e-70 236.7 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 KFQ94391.1 - 4.5e-14 52.7 0.2 5.7e-13 49.1 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFQ94391.1 - 5.7e-12 45.5 0.0 1.1e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFQ94391.1 - 3.5e-11 42.8 0.0 6.9e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFQ94391.1 - 3.1e-10 39.8 0.1 8e-08 31.8 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit zf-B_box PF00643.24 KFQ94391.1 - 9.2e-07 28.9 5.4 9.2e-07 28.9 5.4 4.0 4 0 0 4 4 3 2 B-box zinc finger zf-RING_UBOX PF13445.6 KFQ94391.1 - 1.1e-06 28.6 5.1 1.1e-06 28.6 5.1 2.9 3 0 0 3 3 3 1 RING-type zinc-finger Gtr1_RagA PF04670.12 KFQ94391.1 - 1.2e-06 28.0 0.0 2.9e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region zf-RING_5 PF14634.6 KFQ94391.1 - 1.7e-06 27.8 1.9 1.7e-06 27.8 1.9 4.2 3 1 0 3 3 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFQ94391.1 - 3.4e-05 24.1 3.0 3.4e-05 24.1 3.0 4.2 4 0 0 4 4 4 1 Ring finger domain MMR_HSR1 PF01926.23 KFQ94391.1 - 0.0002 21.4 0.1 0.00078 19.5 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase zf-C3HC4 PF00097.25 KFQ94391.1 - 0.00037 20.3 1.3 0.00037 20.3 1.3 3.8 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFQ94391.1 - 0.0068 16.2 3.6 0.0068 16.2 3.6 3.6 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFQ94391.1 - 0.007 16.2 3.2 0.007 16.2 3.2 3.3 4 0 0 4 4 3 1 Prokaryotic RING finger family 4 Thymidylate_kin PF02223.17 KFQ94391.1 - 0.16 11.6 1.1 2.9 7.5 0.1 2.4 2 0 0 2 2 2 0 Thymidylate kinase FemAB PF02388.16 KFQ94391.1 - 0.46 9.3 1.6 0.42 9.4 0.3 1.5 2 0 0 2 2 2 0 FemAB family Pro_isomerase PF00160.21 KFQ94392.1 - 1.5e-50 171.5 0.1 3.1e-50 170.5 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KFQ94392.1 - 4.8e-11 43.0 2.6 0.065 14.1 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ94392.1 - 0.00099 19.4 0.0 1.4 9.2 0.0 3.6 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF505 PF04458.12 KFQ94392.1 - 0.015 13.7 0.0 0.023 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF505) Ge1_WD40 PF16529.5 KFQ94392.1 - 0.09 11.7 0.3 31 3.4 0.0 3.5 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CENP-K PF11802.8 KFQ94393.1 - 3.2e-105 351.5 15.3 3.6e-105 351.3 15.3 1.0 1 0 0 1 1 1 1 Centromere-associated protein K MIS13 PF08202.11 KFQ94393.1 - 0.016 14.5 8.8 0.019 14.3 8.8 1.2 1 0 0 1 1 1 0 Mis12-Mtw1 protein family CSM2 PF16834.5 KFQ94393.1 - 0.019 14.6 1.0 0.025 14.2 1.0 1.3 1 0 0 1 1 1 0 Shu complex component Csm2, DNA-binding Mit_ribos_Mrp51 PF11709.8 KFQ94393.1 - 0.036 13.7 3.5 0.046 13.3 3.5 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit DUF2063 PF09836.9 KFQ94393.1 - 0.16 12.3 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative DNA-binding domain zf-C4H2 PF10146.9 KFQ94393.1 - 0.24 11.7 4.0 0.4 11.0 4.0 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein DUF2730 PF10805.8 KFQ94393.1 - 0.25 11.5 5.9 0.23 11.6 0.6 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) DUF848 PF05852.11 KFQ94393.1 - 0.42 10.7 6.7 0.67 10.1 6.7 1.4 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Exonuc_VII_L PF02601.15 KFQ94393.1 - 0.65 9.5 3.6 0.78 9.2 3.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit HisKA_2 PF07568.12 KFQ94393.1 - 1.3 9.1 5.1 3.1 8.0 0.8 3.2 3 1 1 4 4 4 0 Histidine kinase DS PF01916.17 KFQ94395.1 - 9.9e-31 107.1 0.0 1.1e-30 106.9 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase UPF0139 PF03669.13 KFQ94396.1 - 3.1e-27 94.3 4.5 3.3e-27 94.2 4.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) protein_MS5 PF04776.12 KFQ94396.1 - 0.0068 16.5 0.0 0.0073 16.4 0.0 1.0 1 0 0 1 1 1 1 Protein MS5 Glyco_transf_29 PF00777.18 KFQ94397.1 - 1.3e-77 260.9 0.0 1.6e-77 260.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) PI3_PI4_kinase PF00454.27 KFQ94398.1 - 2e-41 142.4 1.1 1.9e-28 99.9 0.4 2.9 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KFQ94398.1 - 8.8e-35 119.8 0.0 2.1e-34 118.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Ribosomal_L18_c PF14204.6 KFQ94398.1 - 0.14 13.1 0.2 0.34 11.9 0.2 1.7 1 0 0 1 1 1 0 Ribosomal L18 C-terminal region Serpin PF00079.20 KFQ94399.1 - 2.4e-111 372.7 2.7 3.2e-111 372.2 2.7 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF745 PF05335.13 KFQ94400.1 - 0.00099 18.9 1.8 0.016 14.9 1.1 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF745) DUF5082 PF16888.5 KFQ94400.1 - 0.0022 18.3 9.7 0.0052 17.0 4.6 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF5082) DUF1664 PF07889.12 KFQ94400.1 - 0.0038 17.3 4.3 0.096 12.7 1.6 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1664) PspA_IM30 PF04012.12 KFQ94400.1 - 0.012 15.1 0.5 0.012 15.1 0.5 2.0 3 0 0 3 3 3 0 PspA/IM30 family KxDL PF10241.9 KFQ94400.1 - 0.013 15.8 9.2 0.12 12.6 0.1 3.3 3 1 1 4 4 3 0 Uncharacterized conserved protein DUF677 PF05055.12 KFQ94400.1 - 0.017 14.0 6.3 0.88 8.4 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF677) Fib_alpha PF08702.10 KFQ94400.1 - 0.019 15.1 8.2 2.4 8.3 0.2 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 KFQ94400.1 - 0.05 13.9 0.8 0.84 9.9 0.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) V-SNARE_C PF12352.8 KFQ94400.1 - 0.068 13.5 6.9 0.15 12.4 0.5 2.8 3 1 0 3 3 2 0 Snare region anchored in the vesicle membrane C-terminus DUF5446 PF17522.2 KFQ94400.1 - 0.081 13.1 1.2 7.4 6.8 0.5 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5446) DASH_Duo1 PF08651.10 KFQ94400.1 - 0.089 12.6 2.5 0.41 10.4 0.1 2.6 3 0 0 3 3 3 0 DASH complex subunit Duo1 DUF2203 PF09969.9 KFQ94400.1 - 0.093 13.5 2.5 2.4 8.9 2.0 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) APC_N_CC PF16689.5 KFQ94400.1 - 0.13 12.4 2.7 1.8 8.7 0.1 3.1 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain BLOC1_2 PF10046.9 KFQ94400.1 - 0.17 12.2 9.6 2.6 8.4 2.7 3.2 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CREPT PF16566.5 KFQ94400.1 - 0.29 11.3 7.2 1.1 9.4 4.1 2.5 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Trimer_CC PF08954.11 KFQ94400.1 - 0.38 10.4 4.1 11 5.6 0.1 2.9 2 1 1 3 3 3 0 Trimerisation motif SNARE PF05739.19 KFQ94400.1 - 0.45 10.5 7.0 2.6 8.1 0.2 3.6 4 0 0 4 4 4 0 SNARE domain DUF641 PF04859.12 KFQ94400.1 - 0.47 10.8 6.9 0.78 10.1 0.7 2.6 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) SlyX PF04102.12 KFQ94400.1 - 0.51 11.0 5.4 4.3 8.0 0.5 3.1 3 1 1 4 4 4 0 SlyX DUF4407 PF14362.6 KFQ94400.1 - 0.66 9.3 2.7 5.4 6.3 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) XhlA PF10779.9 KFQ94400.1 - 0.75 10.0 12.6 3.7 7.8 0.1 3.7 3 1 2 5 5 5 0 Haemolysin XhlA BRE1 PF08647.11 KFQ94400.1 - 0.97 9.5 11.8 2.6 8.2 0.4 3.1 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase DUF3552 PF12072.8 KFQ94400.1 - 1.5 8.2 9.3 8.4 5.8 2.3 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF3552) FlaC_arch PF05377.11 KFQ94400.1 - 1.6 9.2 6.1 35 4.9 2.5 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF5089 PF17002.5 KFQ94400.1 - 1.7 8.4 11.8 52 3.6 11.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5089) ADIP PF11559.8 KFQ94400.1 - 3.1 7.9 11.9 0.068 13.3 2.3 2.5 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF16 PF01519.16 KFQ94400.1 - 3.1 8.3 9.8 1.8e+02 2.7 9.5 2.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 Holin_BhlA PF10960.8 KFQ94400.1 - 4 7.5 7.3 0.99 9.4 0.3 2.9 3 0 0 3 3 3 0 BhlA holin family UPF0242 PF06785.11 KFQ94400.1 - 4.1 7.5 12.2 17 5.5 12.2 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Uds1 PF15456.6 KFQ94400.1 - 4.6 7.4 12.3 35 4.6 6.8 3.0 2 1 0 2 2 2 0 Up-regulated During Septation LMBR1 PF04791.16 KFQ94400.1 - 7 5.4 6.5 10 4.9 6.5 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein Clathrin PF00637.20 KFQ94401.1 - 4.9e-211 691.1 44.4 1.1e-34 119.4 2.7 7.9 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KFQ94401.1 - 1.6e-48 160.7 1.6 1.3e-09 37.9 0.0 6.6 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 KFQ94401.1 - 2e-30 104.5 1.9 9.1e-30 102.4 0.3 2.9 3 0 0 3 3 3 1 Clathrin-H-link Clathrin-link PF09268.10 KFQ94401.1 - 4.7e-11 41.8 0.4 1.5e-10 40.2 0.4 2.0 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 KFQ94401.1 - 5.9e-05 22.3 3.9 0.001 18.2 0.1 3.9 3 1 0 4 4 4 1 Coatomer WD associated region TPR_19 PF14559.6 KFQ94401.1 - 0.004 17.6 3.9 42 4.8 0.1 6.4 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ94401.1 - 0.021 14.8 12.9 1.3 9.3 0.3 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Mito_carr PF00153.27 KFQ94402.1 - 4.3e-61 202.9 0.2 4.6e-20 71.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein TSP_1 PF00090.19 KFQ94403.1 - 4e-10 39.7 7.6 4e-10 39.7 7.6 2.2 2 1 0 2 2 2 1 Thrombospondin type 1 domain Somatomedin_B PF01033.17 KFQ94403.1 - 8.9e-07 29.2 20.4 8.9e-07 29.2 20.4 2.3 2 1 0 2 2 2 1 Somatomedin B domain Homeodomain PF00046.29 KFQ94405.1 - 6.6e-23 80.3 4.7 1.2e-22 79.5 4.7 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ94405.1 - 0.0081 16.1 0.0 0.03 14.2 0.1 1.9 2 0 0 2 2 2 1 Homeobox KN domain DUF3437 PF11919.8 KFQ94405.1 - 0.57 10.1 2.5 0.86 9.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Es2 PF09751.9 KFQ94406.1 - 1.2e-69 236.1 7.7 1.2e-69 236.1 7.7 2.3 1 1 1 2 2 2 1 Nuclear protein Es2 RED_C PF07807.11 KFQ94406.1 - 0.96 9.9 4.6 0.3 11.6 0.3 2.4 3 1 0 3 3 3 0 RED-like protein C-terminal region Lectin_C PF00059.21 KFQ94407.1 - 7.5e-21 74.9 0.7 1.3e-20 74.1 0.7 1.4 1 0 0 1 1 1 1 Lectin C-type domain Ldl_recept_a PF00057.18 KFQ94407.1 - 3.2e-11 43.3 7.9 3.2e-11 43.3 7.9 3.5 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A UL45 PF05473.12 KFQ94407.1 - 0.0012 18.5 0.4 0.0028 17.3 0.0 1.7 2 0 0 2 2 2 1 UL45 protein, carbohydrate-binding C-type lectin-like Carb_anhydrase PF00194.21 KFQ94408.1 - 1.3e-81 273.9 0.0 1.4e-81 273.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase C1-set PF07654.15 KFQ94409.1 - 7.3e-29 100.0 0.1 8.5e-29 99.8 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.6 KFQ94409.1 - 6.4e-07 29.9 0.3 7.9e-07 29.6 0.3 1.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFQ94409.1 - 4.8e-06 26.7 0.2 5.9e-06 26.4 0.2 1.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ94409.1 - 7.3e-06 26.0 0.0 9.1e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain C2-set_2 PF08205.12 KFQ94409.1 - 8.7e-06 25.7 0.2 1.1e-05 25.5 0.2 1.1 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 KFQ94409.1 - 5.7e-05 23.4 0.3 7.5e-05 23.0 0.3 1.1 1 0 0 1 1 1 1 Immunoglobulin domain PTCRA PF15028.6 KFQ94409.1 - 0.0013 18.5 0.1 0.0014 18.3 0.1 1.0 1 0 0 1 1 1 1 Pre-T-cell antigen receptor C1-set PF07654.15 KFQ94410.1 - 1e-25 89.9 0.3 1.1e-25 89.8 0.3 1.0 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.6 KFQ94410.1 - 3.2e-07 30.9 0.4 3.9e-07 30.6 0.4 1.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFQ94410.1 - 6.1e-07 29.5 0.7 7.3e-07 29.3 0.7 1.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ94410.1 - 6e-05 23.0 0.1 6.6e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFQ94410.1 - 7.6e-05 23.0 0.7 0.00022 21.5 0.7 1.6 1 1 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 KFQ94410.1 - 0.00022 21.2 0.7 0.00027 21.0 0.7 1.1 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Marek_A PF02124.15 KFQ94410.1 - 0.013 15.4 1.5 0.022 14.6 1.5 1.4 1 1 0 1 1 1 0 Marek's disease glycoprotein A PTCRA PF15028.6 KFQ94410.1 - 0.018 14.7 0.3 0.021 14.5 0.3 1.0 1 0 0 1 1 1 0 Pre-T-cell antigen receptor DUF2262 PF10020.9 KFQ94410.1 - 0.1 13.0 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) Ras PF00071.22 KFQ94411.1 - 2.5e-39 134.5 0.4 3.1e-39 134.2 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ94411.1 - 1.4e-14 54.3 0.2 2.6e-14 53.5 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ94411.1 - 0.0003 20.3 0.1 0.00042 19.8 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF2757 PF10955.8 KFQ94411.1 - 0.00067 19.9 0.1 0.0015 18.7 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2757) GTP_EFTU PF00009.27 KFQ94411.1 - 0.046 13.3 0.0 0.1 12.1 0.0 1.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain G-alpha PF00503.20 KFQ94412.1 - 3.7e-71 240.2 0.0 4.1e-71 240.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFQ94412.1 - 1.7e-08 34.1 0.0 2.6e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family A_deaminase PF00962.22 KFQ94413.1 - 5.3e-131 436.8 1.5 1.3e-130 435.6 1.5 1.6 1 1 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 KFQ94413.1 - 0.08 12.2 0.1 3.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Amidohydrolase family GST_N PF02798.20 KFQ94414.1 - 7.8e-18 64.6 0.0 1.4e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFQ94414.1 - 0.0031 17.9 0.0 0.0072 16.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain SeqA_N PF17206.3 KFQ94414.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 SeqA protein N-terminal domain N2227 PF07942.12 KFQ94415.1 - 2.2e-114 381.2 0.2 2.7e-114 380.9 0.2 1.1 1 0 0 1 1 1 1 N2227-like protein RhoGAP PF00620.27 KFQ94415.1 - 0.0022 17.8 0.2 0.071 12.9 0.1 2.3 1 1 1 2 2 2 1 RhoGAP domain Methyltransf_11 PF08241.12 KFQ94415.1 - 0.03 15.0 0.0 0.075 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KFQ94415.1 - 0.03 15.1 0.0 0.12 13.1 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KFQ94415.1 - 0.078 12.8 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain G-gamma PF00631.22 KFQ94416.1 - 1.5e-11 44.1 0.0 1.6e-11 44.1 0.0 1.0 1 0 0 1 1 1 1 GGL domain Pentapeptide_4 PF13599.6 KFQ94417.1 - 0.004 17.3 0.0 1.1 9.4 0.0 2.0 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) DUF2924 PF11149.8 KFQ94417.1 - 0.62 10.4 3.9 3.2 8.1 3.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2924) Sema PF01403.19 KFQ94418.1 - 1.1e-158 528.6 0.0 1.8e-158 527.9 0.0 1.3 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 KFQ94418.1 - 2e-07 31.4 4.5 6.5e-07 29.8 4.5 2.0 1 0 0 1 1 1 1 Plexin repeat ig PF00047.25 KFQ94418.1 - 1.3e-06 28.5 0.1 3.8e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin domain Ig_5 PF16681.5 KFQ94418.1 - 0.00019 21.8 0.8 0.00068 20.0 0.1 2.3 2 0 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_2 PF13895.6 KFQ94418.1 - 0.00027 21.2 0.0 0.00084 19.6 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFQ94418.1 - 0.00053 20.5 0.0 0.0014 19.2 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ94418.1 - 0.00087 19.3 0.3 0.0024 17.9 0.1 1.8 2 0 0 2 2 2 1 Immunoglobulin I-set domain Pkinase_fungal PF17667.1 KFQ94418.1 - 0.11 11.3 0.0 0.22 10.3 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase DUF5472 PF17566.2 KFQ94418.1 - 0.4 10.7 2.2 9.1 6.3 0.2 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5472) PSI_integrin PF17205.3 KFQ94418.1 - 0.46 10.3 3.5 0.68 9.7 1.6 2.3 2 0 0 2 2 2 0 Integrin plexin domain I-set PF07679.16 KFQ94419.1 - 0.032 14.3 0.2 0.045 13.8 0.2 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain CKS PF01111.19 KFQ94420.1 - 3.7e-29 100.8 1.9 4.2e-29 100.6 1.9 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit PID PF00640.23 KFQ94421.1 - 4.7e-50 169.3 0.0 9.4e-50 168.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.24 KFQ94421.1 - 2.2e-17 62.9 0.1 8.5e-17 61.0 0.0 2.0 2 0 0 2 2 2 1 SH2 domain PTB PF08416.13 KFQ94421.1 - 0.004 17.3 0.1 0.28 11.4 0.0 2.5 2 0 0 2 2 2 1 Phosphotyrosine-binding domain Delta_lysin PF05372.11 KFQ94421.1 - 0.1 11.9 0.1 0.21 10.9 0.1 1.5 1 0 0 1 1 1 0 Delta lysin family GHBP PF12772.7 KFQ94422.1 - 3e-133 444.0 12.1 3.7e-133 443.7 12.1 1.1 1 0 0 1 1 1 1 Growth hormone receptor binding fn3 PF00041.21 KFQ94422.1 - 8.6e-07 29.2 0.2 2e-06 28.1 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III domain EpoR_lig-bind PF09067.10 KFQ94422.1 - 0.0058 16.8 1.6 0.0058 16.8 1.6 2.7 3 0 0 3 3 3 1 Erythropoietin receptor, ligand binding Nab6_mRNP_bdg PF10567.9 KFQ94422.1 - 0.062 12.8 0.3 0.16 11.5 0.3 1.6 1 0 0 1 1 1 0 RNA-recognition motif LEDGF PF11467.8 KFQ94424.1 - 9.9e-29 99.4 5.6 2.6e-28 98.0 5.6 1.8 1 0 0 1 1 1 1 Lens epithelium-derived growth factor (LEDGF) DUF4462 PF14692.6 KFQ94426.1 - 0.17 11.4 0.4 0.48 9.9 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) INSIG PF07281.12 KFQ94427.1 - 2.8e-37 128.4 3.8 2.9e-36 125.1 3.8 2.1 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) KOG2701 PF09762.9 KFQ94428.1 - 4.6e-77 258.2 0.1 4.6e-77 258.2 0.1 4.3 2 1 1 3 3 3 1 Coiled-coil domain-containing protein (DUF2037) Baculo_PEP_C PF04513.12 KFQ94428.1 - 0.58 10.2 11.2 4.7 7.3 6.2 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 KFQ94428.1 - 1.6 9.3 9.7 0.37 11.3 0.5 3.8 1 1 4 5 5 5 0 Nucleopolyhedrovirus P10 protein MerR-DNA-bind PF09278.11 KFQ94428.1 - 5.1 7.7 18.4 0.68 10.5 1.8 4.2 3 0 0 3 3 3 0 MerR, DNA binding DUF2730 PF10805.8 KFQ94428.1 - 7.4 6.7 21.6 0.36 10.9 1.0 4.8 4 1 0 5 5 5 0 Protein of unknown function (DUF2730) DUF1664 PF07889.12 KFQ94428.1 - 8.5 6.4 22.4 1.4 8.9 0.9 4.7 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) 7tm_1 PF00001.21 KFQ94429.1 - 1.2e-68 231.3 10.4 1.5e-68 231.0 10.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFQ94429.1 - 2.7e-07 30.5 2.6 2.7e-07 30.5 2.6 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFQ94429.1 - 8.2e-06 25.4 5.9 1e-05 25.1 4.9 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFQ94429.1 - 0.0036 17.1 1.6 0.0036 17.1 1.6 1.8 2 0 0 2 2 2 1 Olfactory receptor DUF2208 PF09973.9 KFQ94429.1 - 0.0074 15.9 2.6 0.015 14.9 0.1 2.0 2 0 0 2 2 2 1 Predicted membrane protein (DUF2208) OppC_N PF12911.7 KFQ94429.1 - 0.022 14.7 3.8 0.059 13.3 0.0 2.9 2 1 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C MBOAT_2 PF13813.6 KFQ94430.1 - 0.18 12.1 3.4 0.12 12.6 1.8 1.6 1 1 1 2 2 2 0 Membrane bound O-acyl transferase family DEAD PF00270.29 KFQ94431.1 - 6e-47 159.7 0.1 1.3e-46 158.6 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFQ94431.1 - 3.2e-24 85.4 0.0 9.3e-23 80.7 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFQ94431.1 - 1.6e-17 63.5 0.3 2.8e-17 62.7 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KFQ94431.1 - 1.7e-07 31.4 0.0 3.1e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CENP-B_dimeris PF09026.10 KFQ94431.1 - 0.41 11.1 3.5 1 9.8 3.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Actin PF00022.19 KFQ94432.1 - 3.1e-86 289.6 0.0 2.2e-52 178.1 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 KFQ94432.1 - 3.3e-05 22.9 0.0 0.052 12.4 0.0 2.3 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 KFQ94432.1 - 0.018 15.4 0.0 0.043 14.2 0.0 1.8 2 1 0 2 2 2 0 Cell division protein FtsA Robl_LC7 PF03259.17 KFQ94432.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Roadblock/LC7 domain EamA PF00892.20 KFQ94433.1 - 8.6e-11 42.2 41.8 3.6e-06 27.2 5.9 3.2 3 0 0 3 3 3 3 EamA-like transporter family BAGE PF08180.11 KFQ94433.1 - 0.18 11.9 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 B melanoma antigen family MHYT PF03707.16 KFQ94433.1 - 2.2 8.5 7.8 0.88 9.8 0.1 3.4 3 1 0 3 3 3 0 Bacterial signalling protein N terminal repeat 7tm_1 PF00001.21 KFQ94434.1 - 1.3e-35 123.0 9.1 1.3e-35 123.0 9.1 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFQ94434.1 - 6.1e-05 22.5 1.0 6.1e-05 22.5 1.0 2.3 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFQ94434.1 - 0.00018 21.3 5.8 0.0072 16.1 1.8 2.6 2 1 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFQ94434.1 - 0.0024 17.6 4.4 0.0024 17.6 4.4 2.5 2 2 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx UPAR_LY6_2 PF16975.5 KFQ94435.1 - 0.0016 18.6 10.0 0.0021 18.2 10.0 1.1 1 0 0 1 1 1 1 Ly6/PLAUR domain-containing protein 6, Lypd6 NCKAP5 PF15246.6 KFQ94436.1 - 1.4e-125 419.0 25.2 1.4e-125 419.0 25.2 4.8 6 0 0 6 6 6 1 Nck-associated protein 5, Peripheral clock protein FTO_CTD PF12934.7 KFQ94437.1 - 0.092 12.5 9.4 0.2 11.4 0.0 2.4 1 1 1 2 2 2 0 FTO C-terminal domain Cwf_Cwc_15 PF04889.12 KFQ94437.1 - 0.16 11.7 12.1 0.21 11.3 12.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Glyco_transf_18 PF15024.6 KFQ94438.1 - 4.4e-265 880.6 0.5 5.6e-265 880.2 0.5 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 18 DUF4525 PF15027.6 KFQ94438.1 - 1.9e-64 215.5 0.1 3.2e-64 214.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4525) Cation_efflux PF01545.21 KFQ94439.1 - 0.00032 20.5 2.4 0.00032 20.5 2.4 3.4 2 2 1 3 3 3 3 Cation efflux family DUF2157 PF09925.9 KFQ94439.1 - 5.4 6.8 10.0 1.4 8.7 5.1 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) Amidohydro_2 PF04909.14 KFQ94440.1 - 2.5e-62 211.3 0.0 3e-62 211.0 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Cyclin_N PF00134.23 KFQ94441.1 - 1e-15 57.6 1.6 1.4e-12 47.4 0.2 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFQ94441.1 - 1.3 9.1 7.7 5.1 7.2 0.1 3.1 3 0 0 3 3 3 0 Cyclin, C-terminal domain Pkinase PF00069.25 KFQ94442.1 - 3.1e-55 187.4 0.0 3.5e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ94442.1 - 1.1e-37 129.7 0.0 1.3e-37 129.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ94442.1 - 1.1e-06 28.3 0.0 1.9e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFQ94442.1 - 0.00048 19.0 0.0 0.00061 18.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFQ94442.1 - 0.0011 19.0 0.1 0.0029 17.6 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFQ94442.1 - 0.11 11.6 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 KFQ94442.1 - 0.27 10.1 0.0 0.38 9.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Rab3-GTPase_cat PF13890.6 KFQ94443.1 - 2.8e-68 228.7 0.0 9.5e-68 226.9 0.0 1.9 2 0 0 2 2 2 1 Rab3 GTPase-activating protein catalytic subunit SNF2_N PF00176.23 KFQ94444.1 - 3.1e-32 111.7 0.1 5.4e-32 110.9 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFQ94444.1 - 3.5e-16 59.5 0.2 1.4e-14 54.4 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFQ94444.1 - 8.6e-11 42.1 0.3 6.8e-09 36.0 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HNH PF01844.23 KFQ94444.1 - 7.4e-09 35.6 0.1 7.4e-09 35.6 0.1 2.5 2 0 0 2 2 2 1 HNH endonuclease zf-RanBP PF00641.18 KFQ94444.1 - 0.0037 16.5 7.7 0.022 14.1 7.7 2.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others HNH_5 PF14279.6 KFQ94444.1 - 0.009 15.8 0.1 0.009 15.8 0.1 3.7 3 0 0 3 3 3 1 HNH endonuclease ERCC3_RAD25_C PF16203.5 KFQ94444.1 - 0.012 14.8 0.0 0.037 13.3 0.0 1.8 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Flavi_DEAD PF07652.14 KFQ94444.1 - 0.04 13.9 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain Transketolase_C PF02780.20 KFQ94444.1 - 0.15 12.0 0.0 0.69 9.8 0.0 2.1 2 0 0 2 2 2 0 Transketolase, C-terminal domain UBX PF00789.20 KFQ94445.1 - 5.6e-19 68.1 0.0 1.1e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain Glyco_hydro_1 PF00232.18 KFQ94446.1 - 2.4e-179 596.5 0.5 2.7e-179 596.4 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 tRNA-synt_2 PF00152.20 KFQ94447.1 - 3e-78 263.1 0.1 3.8e-78 262.7 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFQ94447.1 - 1.3e-08 34.7 1.0 2.2e-08 33.9 1.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KFQ94447.1 - 9.3e-05 22.0 0.3 0.45 10.0 0.2 2.6 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) S-AdoMet_synt_N PF00438.20 KFQ94447.1 - 0.014 16.1 0.2 0.094 13.4 0.2 2.1 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, N-terminal domain tRNA_anti_2 PF13742.6 KFQ94447.1 - 0.1 12.8 0.1 0.26 11.5 0.1 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain 7tm_1 PF00001.21 KFQ94448.1 - 1.7e-50 171.8 14.8 2e-50 171.5 14.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CXCR4_N PF12109.8 KFQ94448.1 - 2.4e-18 66.0 6.7 4.3e-18 65.2 6.7 1.4 1 0 0 1 1 1 1 CXCR4 Chemokine receptor N terminal 7TM_GPCR_Srsx PF10320.9 KFQ94448.1 - 0.00084 18.8 11.9 0.0013 18.2 11.9 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TctB PF07331.11 KFQ94448.1 - 0.13 12.5 11.5 0.14 12.4 1.9 2.4 1 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family COX2_TM PF02790.15 KFQ94448.1 - 0.47 10.6 0.1 0.47 10.6 0.1 2.6 3 1 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain Methyltransf_23 PF13489.6 KFQ94450.1 - 7e-17 61.7 0.0 9.7e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFQ94450.1 - 6.4e-08 33.3 0.0 1.1e-07 32.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFQ94450.1 - 0.001 18.9 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KFQ94450.1 - 0.042 13.6 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase DUF5099 PF17025.5 KFQ94450.1 - 0.12 12.8 0.1 0.45 11.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5099) BTB PF00651.31 KFQ94451.1 - 7.3e-35 119.6 0.7 4.2e-34 117.1 0.1 2.1 1 1 1 2 2 2 1 BTB/POZ domain MATH PF00917.26 KFQ94451.1 - 1.4e-06 28.4 0.0 2.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 MATH domain Neurexophilin PF06312.12 KFQ94452.1 - 2.7e-97 324.3 4.1 3e-97 324.2 4.1 1.0 1 0 0 1 1 1 1 Neurexophilin Nepo_coat_C PF03688.14 KFQ94452.1 - 0.074 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Nepovirus coat protein, C-terminal domain RVT_1 PF00078.27 KFQ94453.1 - 0.0012 18.5 0.0 0.0035 16.9 0.0 1.7 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFQ94454.1 - 0.0053 16.3 0.0 0.0097 15.4 0.0 1.5 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) EGF PF00008.27 KFQ94455.1 - 8e-09 35.6 23.4 1e-05 25.7 6.4 4.6 5 0 0 5 5 5 2 EGF-like domain hEGF PF12661.7 KFQ94455.1 - 5.7e-05 23.6 16.1 0.00023 21.7 6.0 5.8 5 2 0 5 5 5 2 Human growth factor-like EGF VWD PF00094.25 KFQ94456.1 - 0.0058 16.9 0.3 0.013 15.8 0.3 1.5 1 0 0 1 1 1 1 von Willebrand factor type D domain Ldl_recept_a PF00057.18 KFQ94457.1 - 1.3e-277 895.7 595.2 1.6e-12 47.4 16.4 35.2 34 0 0 34 34 34 31 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 KFQ94457.1 - 2e-173 562.7 81.2 8.5e-10 39.0 0.0 36.6 38 1 0 38 38 38 28 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 KFQ94457.1 - 5.6e-60 199.3 349.3 2.4e-11 43.7 7.9 25.2 19 1 4 23 23 23 13 Coagulation Factor Xa inhibitory site SGL PF08450.12 KFQ94457.1 - 6.5e-21 75.0 29.5 0.00083 19.0 0.3 15.0 10 5 5 15 15 15 6 SMP-30/Gluconolactonase/LRE-like region cEGF PF12662.7 KFQ94457.1 - 1.1e-12 47.7 117.0 0.00011 22.0 0.7 16.3 15 0 0 15 15 15 7 Complement Clr-like EGF-like EGF_CA PF07645.15 KFQ94457.1 - 4.5e-11 42.8 45.4 1.9e-06 27.9 10.8 33.1 27 9 8 35 35 35 4 Calcium-binding EGF domain EGF_3 PF12947.7 KFQ94457.1 - 0.00057 20.0 6.9 0.00057 20.0 6.9 27.2 29 0 0 29 29 29 7 EGF domain EGF_2 PF07974.13 KFQ94457.1 - 0.0046 17.3 6.8 0.0046 17.3 6.8 26.7 26 3 3 29 29 29 4 EGF-like domain TMEM154 PF15102.6 KFQ94457.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Aminotran_5 PF00266.19 KFQ94458.1 - 4.4e-14 52.2 0.0 6e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V RhoGAP PF00620.27 KFQ94459.1 - 9.7e-54 181.3 1.2 1.2e-52 177.7 0.0 2.5 2 1 0 2 2 2 1 RhoGAP domain RPEL PF02755.15 KFQ94459.1 - 0.025 14.3 0.5 0.077 12.7 0.5 1.9 1 0 0 1 1 1 0 RPEL repeat DUF3524 PF12038.8 KFQ94460.1 - 3.3e-73 245.1 0.2 6.9e-73 244.0 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3524) Glycos_transf_1 PF00534.20 KFQ94460.1 - 3.2e-07 30.0 0.0 5.8e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pept_S41_N PF18294.1 KFQ94460.1 - 0.18 11.8 0.0 35 4.5 0.0 2.7 2 0 0 2 2 2 0 Peptidase S41 N-terminal domain zf-H2C2_2 PF13465.6 KFQ94461.1 - 1.3e-32 110.7 61.1 1.2e-07 31.8 5.1 8.7 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ94461.1 - 3.2e-25 87.1 72.8 0.00012 22.4 5.0 8.7 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ94461.1 - 5.4e-16 57.9 69.3 0.0049 17.6 1.0 8.8 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ94461.1 - 2.8e-08 33.8 56.5 0.01 16.1 1.9 9.1 9 0 0 9 9 9 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFQ94461.1 - 3e-08 33.8 1.9 3e-08 33.8 1.9 4.3 4 0 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KFQ94461.1 - 3.7e-08 33.5 54.5 0.0087 16.4 0.4 8.4 8 0 0 8 8 8 4 Zinc-finger of C2H2 type Homeodomain PF00046.29 KFQ94461.1 - 0.00013 21.7 0.0 0.00072 19.4 0.0 2.3 2 0 0 2 2 2 1 Homeodomain zf-H2C2_5 PF13909.6 KFQ94461.1 - 0.0019 17.9 0.4 0.0019 17.9 0.4 6.1 6 1 0 6 6 4 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFQ94461.1 - 0.018 15.0 68.2 0.029 14.4 1.5 8.6 8 0 0 8 8 8 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFQ94461.1 - 0.02 15.2 1.1 0.02 15.2 1.1 7.2 4 3 3 7 7 7 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KFQ94461.1 - 2.7 7.8 33.6 0.11 12.3 0.5 6.7 7 0 0 7 7 7 0 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 KFQ94461.1 - 3.1 8.6 29.5 0.33 11.7 1.5 5.2 4 1 1 5 5 5 0 zinc-ribbon family zf-RING_7 PF02591.15 KFQ94461.1 - 3.9 7.8 8.8 9.2 6.5 0.0 4.2 4 0 0 4 4 4 0 C4-type zinc ribbon domain Actin_micro PF17003.5 KFQ94461.1 - 8.6 5.4 18.8 5.5 6.1 3.6 4.3 2 2 1 3 3 3 0 Putative actin-like family Pkinase PF00069.25 KFQ94462.1 - 3.9e-34 118.2 0.0 6.6e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ94462.1 - 1.3e-31 109.8 0.0 2.2e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Activin_recp PF01064.23 KFQ94462.1 - 6.2e-06 27.2 12.5 6.2e-06 27.2 12.5 2.2 2 0 0 2 2 2 1 Activin types I and II receptor domain Pkinase_fungal PF17667.1 KFQ94462.1 - 2.3e-05 23.4 0.0 3.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KFQ94462.1 - 0.035 13.7 0.0 0.22 11.1 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFQ94462.1 - 0.055 13.4 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Toxin_TOLIP PF00087.21 KFQ94462.1 - 0.24 11.7 9.9 0.83 10.0 9.9 1.9 1 1 0 1 1 1 0 Snake toxin and toxin-like protein PWWP PF00855.17 KFQ94463.1 - 0.00015 22.1 0.0 0.00038 20.8 0.0 1.7 1 0 0 1 1 1 1 PWWP domain MBD PF01429.19 KFQ94463.1 - 0.038 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Methyl-CpG binding domain E_Pc_C PF06752.12 KFQ94464.1 - 4.7e-68 229.7 26.1 1.1e-67 228.5 26.1 1.6 1 0 0 1 1 1 1 Enhancer of Polycomb C-terminus EPL1 PF10513.9 KFQ94464.1 - 1.4e-14 54.7 1.6 1.4e-14 54.7 1.6 4.1 3 1 0 3 3 3 1 Enhancer of polycomb-like CAF1A PF12253.8 KFQ94464.1 - 0.038 14.2 0.8 0.2 11.9 0.0 2.4 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A Kinesin PF00225.23 KFQ94466.1 - 9.7e-111 369.9 0.3 9.7e-111 369.9 0.3 2.4 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KFQ94466.1 - 1e-22 80.7 0.0 1e-22 80.7 0.0 3.6 3 1 1 4 4 4 1 Microtubule binding DASH_Dam1 PF08653.10 KFQ94466.1 - 0.37 10.6 12.4 3.3 7.6 0.6 4.7 3 0 0 3 3 3 0 DASH complex subunit Dam1 PTSIIB_sorb PF03830.15 KFQ94466.1 - 0.92 9.7 8.3 1.8 8.8 0.1 3.9 3 0 0 3 3 3 0 PTS system sorbose subfamily IIB component DUF1799 PF08809.11 KFQ94466.1 - 1.8 8.8 4.0 3.3 7.9 0.3 3.1 2 0 0 2 2 2 0 Phage related hypothetical protein (DUF1799) UPAR_LY6_2 PF16975.5 KFQ94467.1 - 2.3e-54 182.1 16.4 2.8e-54 181.8 16.4 1.1 1 0 0 1 1 1 1 Ly6/PLAUR domain-containing protein 6, Lypd6 UPAR_LY6_2 PF16975.5 KFQ94468.1 - 4.2e-52 174.8 12.3 5e-52 174.6 12.3 1.1 1 0 0 1 1 1 1 Ly6/PLAUR domain-containing protein 6, Lypd6 Toxin_TOLIP PF00087.21 KFQ94468.1 - 1.7 9.0 20.2 3.9 7.8 20.2 1.7 1 1 0 1 1 1 0 Snake toxin and toxin-like protein MMADHC PF10229.9 KFQ94469.1 - 4e-133 443.3 0.0 4.5e-133 443.1 0.0 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein DUF1708 PF08101.11 KFQ94470.1 - 0.14 11.3 0.0 0.14 11.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) Ras PF00071.22 KFQ94471.1 - 5.7e-20 71.5 0.0 7.1e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ94471.1 - 0.00058 20.1 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase NID PF07292.13 KFQ94472.1 - 2.4e-13 50.5 0.2 1.3e-07 32.1 0.0 2.6 2 0 0 2 2 2 2 Nmi/IFP 35 domain (NID) RRM_1 PF00076.22 KFQ94472.1 - 0.0041 16.9 0.0 0.0094 15.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NID PF07292.13 KFQ94473.1 - 4.8e-60 200.2 0.0 2.8e-30 104.8 0.1 2.0 2 0 0 2 2 2 2 Nmi/IFP 35 domain (NID) DUF237 PF03072.14 KFQ94473.1 - 0.002 18.1 0.0 0.0036 17.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF237) CUB PF00431.20 KFQ94474.1 - 1.1e-36 125.5 0.1 2e-36 124.7 0.1 1.4 1 0 0 1 1 1 1 CUB domain Xlink PF00193.17 KFQ94474.1 - 7e-30 103.3 0.4 1.1e-29 102.6 0.4 1.3 1 0 0 1 1 1 1 Extracellular link domain Rif1_N PF12231.8 KFQ94475.1 - 1.9e-77 260.8 6.0 4.3e-77 259.6 6.0 1.7 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Nebulin PF00880.18 KFQ94476.1 - 2.1e-26 91.4 5.2 2.9e-11 43.0 1.5 3.4 3 0 0 3 3 3 3 Nebulin repeat SH3_9 PF14604.6 KFQ94476.1 - 3.7e-15 55.5 0.0 6.2e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFQ94476.1 - 5.3e-14 51.6 0.1 1.8e-13 49.9 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFQ94476.1 - 2e-07 30.6 0.0 7.5e-07 28.7 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain mTERF PF02536.14 KFQ94476.1 - 0.018 13.9 0.6 0.028 13.3 0.3 1.4 1 1 0 1 1 1 0 mTERF Nebulin PF00880.18 KFQ94477.1 - 4e-38 128.8 32.5 1.3e-08 34.5 0.9 9.1 9 0 0 9 9 9 8 Nebulin repeat GspL_C PF12693.7 KFQ94477.1 - 0.00079 19.3 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 GspL periplasmic domain HEPN_AbiV PF18728.1 KFQ94477.1 - 0.035 14.3 0.4 0.071 13.3 0.4 1.5 1 0 0 1 1 1 0 AbiV Neur_chan_LBD PF02931.23 KFQ94478.1 - 6e-68 228.5 1.8 8.5e-68 228.0 1.8 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFQ94478.1 - 2e-48 165.6 0.1 2.6e-48 165.2 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Peptidase_A22B PF04258.13 KFQ94480.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Signal peptide peptidase Peptidase_M74 PF03411.13 KFQ94480.1 - 0.18 11.4 0.0 0.24 10.9 0.0 1.1 1 0 0 1 1 1 0 Penicillin-insensitive murein endopeptidase Ras PF00071.22 KFQ94481.1 - 4.4e-44 149.9 0.0 5.2e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ94481.1 - 2.3e-22 79.4 0.0 3.4e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ94481.1 - 1.1e-05 25.0 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFQ94481.1 - 0.025 14.7 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 KFQ94481.1 - 0.05 13.0 0.0 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein SRPRB PF09439.10 KFQ94481.1 - 0.13 11.6 0.0 0.65 9.4 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KFQ94481.1 - 0.16 11.8 0.0 0.61 10.0 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 KFQ94481.1 - 0.19 11.5 0.0 2 8.2 0.0 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Cnd1 PF12717.7 KFQ94482.1 - 0.002 18.2 9.6 1 9.4 0.1 5.8 4 2 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFQ94482.1 - 0.028 14.7 1.8 6.5 7.3 0.0 5.2 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.6 KFQ94482.1 - 0.64 10.6 3.9 40 4.8 0.0 4.9 5 0 0 5 5 5 0 HEAT-like repeat UQ_con PF00179.26 KFQ94483.1 - 3.5e-42 143.4 0.1 4.3e-42 143.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 KFQ94483.1 - 4e-11 42.6 0.0 9e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.6 KFQ94483.1 - 2e-05 24.3 0.0 2.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KFQ94483.1 - 0.0016 18.7 0.0 0.0024 18.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain UBA_3 PF09288.10 KFQ94483.1 - 0.091 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain DUF2615 PF11027.8 KFQ94484.1 - 8.5e-42 141.6 0.0 1e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) UDPG_MGDP_dh_N PF03721.14 KFQ94485.1 - 1.6e-62 210.4 0.0 3.9e-62 209.1 0.0 1.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KFQ94485.1 - 1.2e-36 125.3 0.0 3.4e-35 120.7 0.0 2.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 KFQ94485.1 - 1.7e-33 114.7 0.0 6.5e-33 112.8 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain 3HCDH_N PF02737.18 KFQ94485.1 - 0.0025 17.7 0.0 0.2 11.5 0.0 2.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 KFQ94485.1 - 0.01 15.9 0.0 3.2 7.8 0.0 3.7 2 2 2 4 4 4 0 lactate/malate dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KFQ94485.1 - 0.034 14.7 0.0 5.7 7.6 0.0 3.3 4 2 0 4 4 4 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KFQ94485.1 - 0.037 14.3 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 KFQ94485.1 - 0.085 13.0 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 KFQ94485.1 - 0.16 11.6 0.0 0.8 9.3 0.0 2.0 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA LIAS_N PF16881.5 KFQ94486.1 - 1.6e-44 150.8 0.5 3e-44 149.9 0.5 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KFQ94486.1 - 1.4e-17 64.6 0.0 2e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Ribosomal_L6 PF00347.23 KFQ94487.1 - 1.6e-33 115.2 1.1 1.6e-16 60.7 0.3 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Glyco_hydro_1 PF00232.18 KFQ94488.1 - 5.2e-164 546.0 16.6 7.6e-81 271.8 1.0 3.1 2 1 1 3 3 3 3 Glycosyl hydrolase family 1 Self-incomp_S1 PF05938.11 KFQ94488.1 - 0.059 13.9 0.0 0.39 11.3 0.0 2.5 1 1 0 1 1 1 0 Plant self-incompatibility protein S1 RFC1 PF08519.12 KFQ94489.1 - 4.5e-59 199.1 0.0 1.1e-58 197.8 0.0 1.8 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KFQ94489.1 - 2.1e-16 60.0 0.0 8.9e-16 58.1 0.0 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KFQ94489.1 - 1.5e-14 54.5 0.0 3.6e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PTCB-BRCT PF12738.7 KFQ94489.1 - 6.9e-07 29.1 0.1 1.9e-06 27.7 0.1 1.8 1 0 0 1 1 1 1 twin BRCT domain Rad17 PF03215.15 KFQ94489.1 - 0.0001 22.3 0.3 0.00087 19.3 0.3 2.3 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 KFQ94489.1 - 0.00016 21.7 0.1 0.001 19.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFQ94489.1 - 0.00045 20.2 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KFQ94489.1 - 0.00092 19.6 0.0 0.0056 17.0 0.0 2.5 1 1 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 KFQ94489.1 - 0.0011 19.3 0.0 0.0055 17.0 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFQ94489.1 - 0.0011 19.3 0.0 0.0036 17.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KFQ94489.1 - 0.0015 18.3 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KFQ94489.1 - 0.0018 18.4 0.0 0.0056 16.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFQ94489.1 - 0.0023 18.5 0.1 0.012 16.1 0.1 2.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFQ94489.1 - 0.0038 17.0 0.0 0.043 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KFQ94489.1 - 0.0039 16.7 0.0 0.009 15.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region BRCT_2 PF16589.5 KFQ94489.1 - 0.014 15.8 0.0 0.047 14.1 0.0 2.0 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain AAA_17 PF13207.6 KFQ94489.1 - 0.043 14.2 0.0 0.043 14.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 KFQ94489.1 - 0.045 13.7 0.1 0.15 12.0 0.1 1.8 1 1 0 1 1 1 0 NTPase WD40_3 PF15911.5 KFQ94490.1 - 1.1e-28 99.0 1.2 7.7e-28 96.3 0.1 3.1 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ94490.1 - 1e-12 48.1 0.5 0.012 15.9 0.1 5.7 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 KFQ94490.1 - 2.3e-11 43.8 6.5 0.00033 20.5 0.1 5.2 3 1 2 6 6 6 4 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 KFQ94490.1 - 3.5e-07 29.7 6.1 0.084 11.9 0.0 4.5 5 0 0 5 5 5 3 Coatomer WD associated region WD40 PF00400.32 KFQ94490.1 - 2.8e-05 24.8 6.7 7 7.7 0.1 6.7 6 0 0 6 6 6 1 WD domain, G-beta repeat eIF2A PF08662.11 KFQ94490.1 - 0.00079 19.3 0.1 0.016 15.1 0.0 2.6 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KFQ94490.1 - 0.0025 15.9 0.8 0.43 8.5 0.0 3.1 2 1 0 2 2 2 1 IKI3 family TPR_8 PF13181.6 KFQ94490.1 - 0.008 16.3 14.5 1.5 9.2 0.2 7.2 9 0 0 9 9 7 1 Tetratricopeptide repeat Mcl1_mid PF12341.8 KFQ94490.1 - 0.022 14.1 0.0 0.19 11.0 0.0 2.5 2 1 1 3 3 3 0 Minichromosome loss protein, Mcl1, middle region TPR_12 PF13424.6 KFQ94490.1 - 0.054 13.8 6.7 32 4.9 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ94490.1 - 0.056 13.7 6.8 13 6.1 1.1 4.8 2 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.6 KFQ94490.1 - 0.16 11.4 8.7 0.22 10.9 1.9 2.9 1 1 2 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_14 PF13428.6 KFQ94490.1 - 0.16 12.9 12.3 12 7.0 0.2 7.0 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ94490.1 - 0.25 11.6 21.4 4.3 7.7 0.4 7.3 7 0 0 7 7 6 0 Tetratricopeptide repeat PD40 PF07676.12 KFQ94490.1 - 0.4 10.7 1.2 1.2e+02 2.7 0.1 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DZR PF12773.7 KFQ94490.1 - 0.54 10.3 10.9 6.2 6.9 10.9 2.5 1 1 0 1 1 1 0 Double zinc ribbon TPR_7 PF13176.6 KFQ94490.1 - 0.65 10.2 10.6 6.5 7.0 0.1 5.8 6 1 0 6 6 5 0 Tetratricopeptide repeat TMEM156 PF15106.6 KFQ94491.1 - 3.1e-90 301.6 13.2 3.9e-90 301.2 13.2 1.1 1 0 0 1 1 1 1 TMEM156 protein family Renin_r PF07850.14 KFQ94491.1 - 0.0062 17.1 0.9 0.012 16.2 0.3 1.9 2 0 0 2 2 2 1 Renin receptor-like protein DUF719 PF05334.13 KFQ94492.1 - 3.1e-65 219.9 3.6 3.1e-65 219.9 3.6 3.0 3 2 0 3 3 3 1 Protein of unknown function (DUF719) DUF4347 PF14252.6 KFQ94492.1 - 0.0085 16.0 0.1 0.0085 16.0 0.1 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF4347) TetR_C_24 PF17932.1 KFQ94492.1 - 0.11 12.7 0.1 0.41 10.9 0.1 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TIR PF01582.20 KFQ94493.1 - 8e-23 81.1 0.4 1.4e-22 80.3 0.1 1.6 2 0 0 2 2 2 1 TIR domain LRR_8 PF13855.6 KFQ94493.1 - 3.8e-18 65.0 11.4 1.3e-08 34.4 0.6 4.5 3 2 1 4 4 4 3 Leucine rich repeat TIR_2 PF13676.6 KFQ94493.1 - 2.6e-15 57.0 0.1 9.3e-15 55.3 0.0 2.0 2 0 0 2 2 2 1 TIR domain LRR_4 PF12799.7 KFQ94493.1 - 3.6e-13 49.4 35.9 1.5e-05 25.3 1.9 7.6 6 2 1 8 8 8 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFQ94493.1 - 6.6e-05 22.9 12.7 3.8 8.4 0.1 7.5 5 1 1 6 6 6 1 Leucine Rich Repeat LRR_9 PF14580.6 KFQ94493.1 - 0.00027 20.5 3.4 0.09 12.3 0.2 2.9 1 1 0 2 2 2 2 Leucine-rich repeat LRRCT PF01463.24 KFQ94493.1 - 0.00068 20.0 0.3 0.0046 17.4 0.0 2.6 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain LRR_6 PF13516.6 KFQ94493.1 - 0.03 14.4 25.5 0.04 14.0 0.3 7.3 9 0 0 9 9 9 0 Leucine Rich repeat baeRF_family7 PF18849.1 KFQ94494.1 - 0.076 13.2 0.0 0.076 13.2 0.0 1.7 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 7 TIR PF01582.20 KFQ94495.1 - 1.6e-24 86.7 0.5 1.6e-24 86.7 0.5 1.6 2 0 0 2 2 2 1 TIR domain LRR_8 PF13855.6 KFQ94495.1 - 1e-18 66.8 13.7 2.6e-09 36.7 1.2 4.7 2 2 2 4 4 4 3 Leucine rich repeat TIR_2 PF13676.6 KFQ94495.1 - 1.3e-15 58.0 0.1 5.7e-15 56.0 0.1 2.1 2 1 1 3 3 3 1 TIR domain LRR_4 PF12799.7 KFQ94495.1 - 3e-15 56.1 25.3 4e-06 27.1 0.4 6.0 5 2 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFQ94495.1 - 3.3e-06 26.7 17.8 0.034 14.2 0.3 6.5 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 KFQ94495.1 - 4.2e-06 26.6 17.6 3.2 8.7 0.1 8.1 6 1 1 7 7 7 2 Leucine Rich Repeat LRRCT PF01463.24 KFQ94495.1 - 0.0002 21.7 0.2 0.0022 18.4 0.0 2.9 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain LRR_9 PF14580.6 KFQ94495.1 - 0.0011 18.5 3.4 0.03 13.8 0.3 2.7 1 1 0 2 2 2 1 Leucine-rich repeat baeRF_family7 PF18849.1 KFQ94496.1 - 0.076 13.2 0.0 0.076 13.2 0.0 1.7 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 7 zf-C2H2 PF00096.26 KFQ94497.1 - 3.6e-17 61.8 23.8 2e-06 27.9 2.7 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ94497.1 - 9.8e-13 47.9 8.7 3.1e-09 36.8 1.0 4.4 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ94497.1 - 3.5e-08 33.6 21.9 0.0022 18.7 1.8 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ94497.1 - 0.1 12.9 3.7 8.3 6.8 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFQ94497.1 - 0.11 12.5 9.4 0.38 10.8 0.6 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 KFQ94497.1 - 0.12 12.8 5.2 7.5 7.1 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 KFQ94497.1 - 0.64 10.1 4.3 3.7 7.7 2.9 2.1 1 1 2 3 3 3 0 Aberrant zinc-finger FOXP-CC PF16159.5 KFQ94497.1 - 1.2 9.9 8.0 4.6 7.9 0.7 3.1 2 1 1 3 3 3 0 FOXP coiled-coil domain RabGAP-TBC PF00566.18 KFQ94498.1 - 1.3e-53 181.8 0.7 4.9e-53 180.0 0.7 2.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3350 PF11830.8 KFQ94498.1 - 5.1e-22 78.0 1.8 5.1e-22 78.0 1.8 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3350) PID PF00640.23 KFQ94498.1 - 4.9e-13 49.3 5.2 8.7e-09 35.5 0.5 3.2 3 0 0 3 3 3 2 Phosphotyrosine interaction domain (PTB/PID) RnlB_antitoxin PF15933.5 KFQ94498.1 - 0.11 12.8 2.1 0.35 11.2 2.1 1.9 1 0 0 1 1 1 0 Antitoxin to bacterial toxin RNase LS or RnlA BET PF17035.5 KFQ94498.1 - 0.24 11.6 2.2 23 5.2 0.1 3.1 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation FANCI_S1-cap PF14674.6 KFQ94498.1 - 6.3 7.0 6.1 5.7 7.1 0.2 2.8 2 0 0 2 2 2 0 FANCI solenoid 1 cap PGM_PMM_I PF02878.16 KFQ94499.1 - 1.5e-36 125.1 0.0 2.8e-36 124.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KFQ94499.1 - 2.2e-24 86.0 0.0 6.9e-24 84.4 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KFQ94499.1 - 3.3e-12 46.6 0.2 1.5e-11 44.5 0.0 2.3 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 KFQ94499.1 - 6.7e-06 26.2 0.0 1.9e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RELT PF12606.8 KFQ94500.1 - 6.7e-26 89.0 0.9 1.1e-25 88.4 0.9 1.3 1 0 0 1 1 1 1 Tumour necrosis factor receptor superfamily member 19 Dmrt1 PF12374.8 KFQ94500.1 - 0.057 13.9 0.2 0.057 13.9 0.2 2.1 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 DUF3169 PF11368.8 KFQ94500.1 - 0.13 11.7 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF4699 PF15770.5 KFQ94501.1 - 8.8e-103 344.3 19.7 9.8e-103 344.2 19.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4699) AAA_22 PF13401.6 KFQ94502.1 - 2.3e-05 24.7 0.1 0.00013 22.3 0.0 2.4 3 0 0 3 3 3 1 AAA domain ANAPC4_WD40 PF12894.7 KFQ94502.1 - 5.1e-05 23.5 5.2 20 5.5 0.1 6.6 4 3 2 6 6 6 0 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KFQ94502.1 - 6.9e-05 22.8 0.1 0.00033 20.6 0.1 2.2 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.6 KFQ94502.1 - 0.00045 20.6 0.0 0.0012 19.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 KFQ94502.1 - 0.0014 18.9 0.0 0.0033 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFQ94502.1 - 0.0032 17.9 0.0 0.015 15.7 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PQQ_2 PF13360.6 KFQ94502.1 - 0.021 14.4 0.0 0.69 9.4 0.0 2.8 2 1 0 2 2 2 0 PQQ-like domain STN1_2 PF09170.10 KFQ94502.1 - 0.058 13.6 0.2 0.2 11.9 0.2 1.9 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 WD40 PF00400.32 KFQ94502.1 - 0.2 12.6 1.0 19 6.3 0.2 4.8 5 0 0 5 5 5 0 WD domain, G-beta repeat Death PF00531.22 KFQ94503.1 - 9e-06 25.8 1.8 1.8e-05 24.8 1.8 1.6 1 0 0 1 1 1 1 Death domain AGH PF17558.2 KFQ94503.1 - 0.11 12.6 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 Androgenic gland hormone ZU5 PF00791.20 KFQ94503.1 - 0.24 11.8 0.8 14 6.1 0.0 3.1 3 0 0 3 3 3 0 ZU5 domain PH PF00169.29 KFQ94504.1 - 3e-46 156.2 16.4 3.7e-11 43.5 0.3 5.8 5 0 0 5 5 5 5 PH domain RhoGAP PF00620.27 KFQ94504.1 - 7.9e-42 142.6 0.3 3.1e-41 140.7 0.1 2.2 2 0 0 2 2 2 1 RhoGAP domain ArfGap PF01412.18 KFQ94504.1 - 3.9e-33 114.0 0.1 3e-32 111.2 0.1 2.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH_6 PF15406.6 KFQ94504.1 - 6.7e-11 42.5 0.4 6.1e-05 23.3 0.1 3.9 3 0 0 3 3 3 2 Pleckstrin homology domain PH_11 PF15413.6 KFQ94504.1 - 1.9e-09 37.9 17.8 0.17 12.3 0.9 7.5 5 2 0 5 5 5 4 Pleckstrin homology domain SAM_2 PF07647.17 KFQ94504.1 - 8e-09 35.5 0.0 4.6e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH_8 PF15409.6 KFQ94504.1 - 2.4e-08 34.2 9.1 0.3 11.4 0.0 5.6 5 0 0 5 5 5 3 Pleckstrin homology domain PH_3 PF14593.6 KFQ94504.1 - 3.3e-06 27.1 5.2 0.013 15.6 0.1 4.2 4 0 0 4 4 4 2 PH domain SAM_1 PF00536.30 KFQ94504.1 - 1.7e-05 25.2 0.0 5.7e-05 23.5 0.0 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KFQ94504.1 - 2e-05 25.1 0.0 7.2e-05 23.4 0.0 2.0 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PH_2 PF08458.10 KFQ94504.1 - 0.0018 18.6 0.6 3.8 7.9 0.0 3.0 3 0 0 3 3 2 2 Plant pleckstrin homology-like region Nup188_C PF18378.1 KFQ94504.1 - 0.02 13.7 0.1 0.088 11.6 0.0 2.0 2 0 0 2 2 2 0 Nuclear pore protein NUP188 C-terminal domain Mcp5_PH PF12814.7 KFQ94504.1 - 0.031 14.4 3.5 2.1 8.5 0.0 3.9 4 0 0 4 4 4 0 Meiotic cell cortex C-terminal pleckstrin homology PH_13 PF16652.5 KFQ94504.1 - 0.09 12.6 8.0 0.75 9.6 0.1 3.2 3 0 0 3 3 2 0 Pleckstrin homology domain T6SS-SciN PF12790.7 KFQ94504.1 - 0.11 12.2 0.3 10 5.9 0.0 2.8 2 0 0 2 2 2 0 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 DUF1030 PF06270.11 KFQ94504.1 - 0.15 11.8 0.0 0.43 10.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1030) Carm_PH PF17888.1 KFQ94504.1 - 0.89 10.0 2.6 11 6.4 0.1 3.4 3 0 0 3 3 3 0 Carmil pleckstrin homology domain RasGAP PF00616.19 KFQ94505.1 - 3.9e-60 203.1 3.4 5.9e-60 202.5 0.0 2.7 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KFQ94505.1 - 4e-38 130.7 13.6 4e-38 130.7 13.6 3.4 3 0 0 3 3 3 1 RasGAP C-terminus IQ PF00612.27 KFQ94505.1 - 8.6e-20 68.6 19.8 5.4e-06 25.7 0.6 5.4 5 0 0 5 5 5 4 IQ calmodulin-binding motif WW PF00397.26 KFQ94505.1 - 0.0021 18.1 4.2 0.0048 16.9 4.2 1.6 1 0 0 1 1 1 1 WW domain bZIP_1 PF00170.21 KFQ94505.1 - 0.012 15.7 1.4 0.012 15.7 1.4 3.9 3 0 0 3 3 3 0 bZIP transcription factor Nif11 PF07862.11 KFQ94505.1 - 0.059 13.7 1.6 4.7 7.6 0.1 3.4 2 0 0 2 2 2 0 Nif11 domain RVT_1 PF00078.27 KFQ94507.1 - 0.0088 15.6 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 KFQ94508.1 - 9.7e-67 225.1 0.0 1.1e-66 224.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ94508.1 - 3.1e-33 115.1 0.0 3.9e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ94508.1 - 1.1e-07 31.5 0.0 2.3e-07 30.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFQ94508.1 - 0.0048 16.9 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFQ94508.1 - 0.016 14.1 0.2 0.022 13.7 0.2 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KFQ94508.1 - 0.043 12.6 0.0 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase CagZ PF09053.10 KFQ94508.1 - 0.18 11.4 0.1 0.4 10.3 0.1 1.6 2 0 0 2 2 2 0 CagZ I-set PF07679.16 KFQ94509.1 - 5.8e-158 513.5 0.0 1.4e-15 57.1 0.0 13.3 13 0 0 13 13 13 12 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ94509.1 - 2e-151 492.9 20.4 1e-13 51.7 0.0 14.2 13 0 0 13 13 13 12 Immunoglobulin domain ig PF00047.25 KFQ94509.1 - 2e-104 341.9 0.0 1.2e-09 38.1 0.0 13.7 13 0 0 13 13 13 12 Immunoglobulin domain Ig_2 PF13895.6 KFQ94509.1 - 4.7e-88 289.6 10.8 3.8e-10 39.9 0.0 13.2 13 0 0 13 13 13 11 Immunoglobulin domain V-set PF07686.17 KFQ94509.1 - 1.5e-49 166.7 22.2 0.00054 20.1 0.0 16.3 12 6 0 12 12 12 10 Immunoglobulin V-set domain LRR_8 PF13855.6 KFQ94509.1 - 1.2e-30 105.1 14.0 6.4e-12 45.1 1.2 5.1 2 1 3 5 5 5 4 Leucine rich repeat Ig_6 PF18452.1 KFQ94509.1 - 1.2e-23 82.4 0.0 0.02 14.4 0.0 11.2 11 0 0 11 11 11 5 Immunoglobulin domain Izumo-Ig PF16706.5 KFQ94509.1 - 3.9e-20 71.7 0.5 0.71 10.0 0.0 11.5 11 0 0 11 11 11 3 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFQ94509.1 - 4.1e-10 39.9 0.0 9 6.8 0.0 10.6 12 1 0 12 12 12 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain LRR_4 PF12799.7 KFQ94509.1 - 4.9e-10 39.5 6.0 0.0012 19.2 0.0 4.4 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) Ig_C17orf99 PF17736.1 KFQ94509.1 - 2.3e-08 34.0 0.5 2.4 8.3 0.0 8.5 11 0 0 11 11 10 1 C17orf99 Ig domain Receptor_2B4 PF11465.8 KFQ94509.1 - 3.3e-08 33.7 0.7 3.9 7.7 0.0 7.7 9 0 0 9 9 8 1 Natural killer cell receptor 2B4 LRR_5 PF13306.6 KFQ94509.1 - 2.3e-06 27.6 2.6 2.7e-06 27.3 0.0 2.5 3 0 0 3 3 2 1 BspA type Leucine rich repeat region (6 copies) Ig_4 PF16680.5 KFQ94509.1 - 0.0003 21.0 3.6 12 6.3 0.0 8.5 11 1 0 11 11 10 0 T-cell surface glycoprotein CD3 delta chain C2-set PF05790.15 KFQ94509.1 - 0.0014 18.8 0.9 0.5 10.6 0.0 5.3 6 0 0 6 6 6 1 Immunoglobulin C2-set domain LRRNT PF01462.18 KFQ94509.1 - 0.0074 15.9 1.9 0.023 14.3 1.9 2.0 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain AMP-binding_C_2 PF14535.6 KFQ94509.1 - 0.17 12.2 0.3 13 6.2 0.0 3.8 5 0 0 5 5 4 0 AMP-binding enzyme C-terminal domain LRR_1 PF00560.33 KFQ94509.1 - 5.4 8.0 8.1 31 5.6 0.3 5.3 7 0 0 7 7 5 0 Leucine Rich Repeat Zot PF05707.12 KFQ94510.1 - 0.15 11.6 0.0 0.3 10.7 0.0 1.4 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) Sulfatase PF00884.23 KFQ94511.1 - 2.2e-85 286.8 0.0 2.7e-85 286.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KFQ94511.1 - 8.5e-50 168.6 0.2 1.3e-49 168.0 0.2 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 KFQ94511.1 - 9.6e-10 38.6 0.1 0.00024 20.8 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KFQ94511.1 - 0.082 13.2 0.0 21 5.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 KFQ94512.1 - 6e-49 165.9 0.3 1e-48 165.1 0.3 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Sulfatase PF00884.23 KFQ94512.1 - 5e-43 147.6 0.0 8.1e-43 147.0 0.0 1.3 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFQ94512.1 - 0.00054 19.7 0.0 0.00088 19.0 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.16 KFQ94512.1 - 0.048 12.6 0.7 0.069 12.1 0.7 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily Glyco_transf_8 PF01501.20 KFQ94513.1 - 8e-21 74.8 0.0 1.8e-18 67.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 KFQ94513.1 - 0.0027 17.7 0.0 0.004 17.1 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.8 KFQ94513.1 - 0.0038 16.6 0.0 0.0056 16.1 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative CD99L2 PF12301.8 KFQ94514.1 - 1.2e-13 51.6 0.5 1.5e-12 48.1 0.3 2.2 1 1 0 1 1 1 1 CD99 antigen like protein 2 DUF5323 PF17257.2 KFQ94514.1 - 0.044 13.7 1.2 0.33 10.9 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5323) CD99L2 PF12301.8 KFQ94515.1 - 7.6e-17 62.1 0.6 7.6e-17 62.1 0.6 1.2 1 0 0 1 1 1 1 CD99 antigen like protein 2 Glycophorin_A PF01102.18 KFQ94515.1 - 0.085 13.1 0.0 0.092 13.0 0.0 1.1 1 0 0 1 1 1 0 Glycophorin A adh_short PF00106.25 KFQ94516.1 - 1.1e-18 67.5 0.0 7.1e-18 64.8 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFQ94516.1 - 9.2e-10 38.5 0.0 4.9e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_2 PF00891.18 KFQ94517.1 - 5.4e-85 284.0 0.0 8.5e-85 283.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KFQ94517.1 - 9e-34 115.3 0.1 1.9e-33 114.3 0.1 1.6 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_25 PF13649.6 KFQ94517.1 - 8.5e-08 32.8 0.0 1.8e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFQ94517.1 - 1.3e-05 25.1 0.0 2.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFQ94517.1 - 1.6e-05 25.6 0.0 3.1e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFQ94517.1 - 1.7e-05 25.4 0.0 4.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFQ94517.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.11 KFQ94517.1 - 0.0057 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain MTS PF05175.14 KFQ94517.1 - 0.0093 15.5 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 KFQ94517.1 - 0.029 13.4 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PerB PF06590.11 KFQ94517.1 - 0.18 12.3 0.0 0.34 11.4 0.0 1.4 1 0 0 1 1 1 0 PerB protein RRM_1 PF00076.22 KFQ94518.1 - 0.0019 18.0 0.5 2.5 8.0 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 7tm_1 PF00001.21 KFQ94519.1 - 2.5e-42 145.0 27.0 3.5e-42 144.6 27.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFQ94519.1 - 0.04 13.3 26.8 0.057 12.8 26.8 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv VHS PF00790.19 KFQ94519.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 VHS domain Methyltransf_2 PF00891.18 KFQ94520.1 - 4.1e-55 186.3 0.0 7.3e-55 185.5 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Maf PF02545.14 KFQ94520.1 - 3.3e-44 150.7 0.0 5.3e-44 150.0 0.0 1.4 1 0 0 1 1 1 1 Maf-like protein Dimerisation2 PF16864.5 KFQ94520.1 - 6.2e-32 109.4 0.0 1.8e-31 108.0 0.0 1.9 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_23 PF13489.6 KFQ94520.1 - 4.1e-06 26.7 0.0 1.7e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFQ94520.1 - 2.6e-05 24.8 0.0 9.8e-05 23.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFQ94520.1 - 0.00019 22.1 0.0 0.00061 20.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Mito_carr PF00153.27 KFQ94521.1 - 6.4e-56 186.3 2.3 4.7e-23 80.9 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 KFQ94521.1 - 0.071 12.3 0.1 0.43 9.7 0.1 1.9 2 0 0 2 2 2 0 Fuseless IL6Ra-bind PF09240.10 KFQ94522.1 - 5e-23 81.3 0.1 7.9e-23 80.7 0.1 1.3 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.10 KFQ94522.1 - 0.00033 20.8 0.6 0.00068 19.8 0.3 1.6 2 0 0 2 2 2 1 Erythropoietin receptor, ligand binding IL4Ra_N PF09238.10 KFQ94522.1 - 0.023 15.0 0.5 0.023 15.0 0.5 1.6 2 0 0 2 2 2 0 Interleukin-4 receptor alpha chain, N-terminal IL2RB_N1 PF18707.1 KFQ94522.1 - 0.047 14.2 0.4 0.75 10.4 0.4 2.4 1 1 0 1 1 1 0 Interleukin-2 receptor subunit beta N-terminal domain 1 IL6Ra-bind PF09240.10 KFQ94523.1 - 8.4e-23 80.6 0.2 1.2e-22 80.1 0.2 1.2 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.10 KFQ94523.1 - 0.0004 20.6 0.3 0.00071 19.7 0.3 1.4 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding IL4Ra_N PF09238.10 KFQ94523.1 - 0.013 15.8 0.5 0.025 14.9 0.5 1.4 1 0 0 1 1 1 0 Interleukin-4 receptor alpha chain, N-terminal IL2RB_N1 PF18707.1 KFQ94523.1 - 0.058 13.9 1.5 1.2 9.7 1.5 2.6 1 1 0 1 1 1 0 Interleukin-2 receptor subunit beta N-terminal domain 1 IL6Ra-bind PF09240.10 KFQ94524.1 - 7.2e-23 80.8 0.7 7.2e-23 80.8 0.7 1.6 2 0 0 2 2 2 1 Interleukin-6 receptor alpha chain, binding MurB_C PF02873.16 KFQ94524.1 - 0.078 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain Somatostatin PF03002.15 KFQ94524.1 - 5.9 6.9 7.5 8 6.5 0.1 3.3 3 0 0 3 3 3 0 Somatostatin/Cortistatin family DUF2434 PF10361.9 KFQ94526.1 - 0.073 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) Tissue_fac PF01108.17 KFQ94526.1 - 0.092 12.6 0.5 0.35 10.7 0.1 2.1 2 0 0 2 2 2 0 Tissue factor LAX PF15681.5 KFQ94526.1 - 0.1 11.4 0.6 0.2 10.4 0.6 1.4 1 0 0 1 1 1 0 Lymphocyte activation family X Ribosomal_S5_C PF03719.15 KFQ94527.1 - 1.3e-24 85.4 0.2 2.2e-24 84.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KFQ94527.1 - 1.9e-15 56.6 2.5 1.9e-15 56.6 2.5 2.1 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Connexin PF00029.19 KFQ94528.1 - 2.1e-69 233.9 1.0 9.2e-43 146.7 0.1 2.0 1 1 1 2 2 2 2 Connexin Cytochrom_B_N_2 PF13631.6 KFQ94528.1 - 0.022 14.8 0.5 0.069 13.1 0.1 1.8 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Fungus-induced PF10917.8 KFQ94528.1 - 0.12 12.8 0.3 1.9 8.8 0.1 2.2 2 0 0 2 2 2 0 Fungus-induced protein Thyroglobulin_1 PF00086.18 KFQ94529.1 - 2.5e-20 71.9 0.7 6.1e-20 70.7 0.7 1.7 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat IGFBP PF00219.18 KFQ94529.1 - 0.0012 19.5 6.8 0.0012 19.5 6.8 3.0 3 0 0 3 3 3 1 Insulin-like growth factor binding protein Neuroparsin PF07327.11 KFQ94529.1 - 3 8.4 9.6 0.36 11.3 1.9 2.9 3 1 0 3 3 3 0 Neuroparsin PTB PF08416.13 KFQ94530.1 - 1.9e-26 92.7 0.0 3.2e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH2 PF00017.24 KFQ94530.1 - 2.2e-09 37.3 0.0 4.6e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 SH2 domain PID PF00640.23 KFQ94530.1 - 0.069 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) Toxin_11 PF07473.11 KFQ94530.1 - 8.3 6.6 6.2 20 5.4 0.2 2.9 2 0 0 2 2 2 0 Spasmodic peptide gm9a; conotoxin from Conus species HMG_box PF00505.19 KFQ94531.1 - 3e-18 66.0 1.7 3e-18 66.0 1.7 2.6 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFQ94531.1 - 4.4e-06 27.2 0.6 4.4e-06 27.2 0.6 2.6 2 0 0 2 2 2 1 HMG-box domain Filament PF00038.21 KFQ94532.1 - 4.7e-22 79.0 19.2 7.4e-22 78.3 19.2 1.3 1 0 0 1 1 1 1 Intermediate filament protein DUF1664 PF07889.12 KFQ94532.1 - 0.15 12.1 0.1 0.15 12.1 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FUSC PF04632.12 KFQ94532.1 - 0.26 9.8 6.4 0.33 9.4 6.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family TPR_MLP1_2 PF07926.12 KFQ94532.1 - 0.35 10.9 15.1 0.064 13.3 7.4 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein BST2 PF16716.5 KFQ94532.1 - 1.2 9.8 11.2 0.49 11.0 4.0 2.8 1 1 1 3 3 3 0 Bone marrow stromal antigen 2 V_ATPase_I PF01496.19 KFQ94532.1 - 1.2 7.0 8.4 1.4 6.7 8.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FliJ PF02050.16 KFQ94532.1 - 1.7 8.8 16.7 6 7.1 2.8 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein UPF0242 PF06785.11 KFQ94532.1 - 1.9 8.6 17.5 0.19 11.8 11.9 2.0 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 KFQ94532.1 - 2.3 7.0 17.2 2.1 7.2 15.4 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 KFQ94532.1 - 5.2 7.7 16.3 1.4 9.6 11.8 2.4 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Macoilin PF09726.9 KFQ94532.1 - 5.5 5.4 12.8 6.5 5.2 12.8 1.2 1 0 0 1 1 1 0 Macoilin family Filament PF00038.21 KFQ94533.1 - 6.6e-110 367.5 18.2 7.4e-110 367.4 18.2 1.0 1 0 0 1 1 1 1 Intermediate filament protein DUF4407 PF14362.6 KFQ94533.1 - 7.3e-06 25.5 9.7 0.059 12.7 2.3 3.0 1 1 2 3 3 3 3 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 KFQ94533.1 - 5.5e-05 23.2 1.5 5.5e-05 23.2 1.5 4.0 3 1 0 3 3 3 1 TPR/MLP1/MLP2-like protein UPF0242 PF06785.11 KFQ94533.1 - 0.0011 19.1 10.4 0.07 13.2 0.0 2.4 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus DUF1257 PF06868.11 KFQ94533.1 - 0.028 14.7 0.2 0.086 13.1 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) APG6_N PF17675.1 KFQ94533.1 - 0.032 14.8 25.5 0.087 13.4 1.8 3.6 3 1 0 3 3 3 0 Apg6 coiled-coil region SlyX PF04102.12 KFQ94533.1 - 0.036 14.7 15.0 4.4 8.0 0.5 4.3 4 1 0 4 4 3 0 SlyX FlxA PF14282.6 KFQ94533.1 - 0.17 11.9 17.6 1.6 8.8 9.7 3.0 1 1 0 2 2 2 0 FlxA-like protein Prefoldin_2 PF01920.20 KFQ94533.1 - 0.28 11.2 20.1 2.4 8.2 1.0 4.5 3 1 1 4 4 4 0 Prefoldin subunit T2SSM PF04612.12 KFQ94533.1 - 0.63 10.1 5.9 0.22 11.6 0.2 2.6 2 2 0 2 2 2 0 Type II secretion system (T2SS), protein M DUF1664 PF07889.12 KFQ94533.1 - 0.87 9.6 10.3 18 5.4 0.1 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 KFQ94533.1 - 1.6 7.8 14.0 2.7 7.0 6.6 2.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TolA_bind_tri PF16331.5 KFQ94533.1 - 1.7 8.7 30.3 4.9 7.3 2.1 4.8 3 2 1 4 4 4 0 TolA binding protein trimerisation COG2 PF06148.11 KFQ94533.1 - 2.1 8.5 11.9 2.8 8.0 0.8 4.0 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 ADIP PF11559.8 KFQ94533.1 - 3.1 7.9 20.5 9.7 6.3 0.8 3.9 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding CHDCT2 PF08074.11 KFQ94533.1 - 3.9 7.6 9.3 1.9 8.6 2.2 2.5 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain Phage_Mu_Gam PF07352.12 KFQ94533.1 - 4.5 7.2 17.6 5.3 6.9 0.7 4.7 3 1 0 4 4 4 0 Bacteriophage Mu Gam like protein DivIC PF04977.15 KFQ94533.1 - 5.2 6.9 26.7 1.5 8.7 1.7 5.0 5 1 1 6 6 6 0 Septum formation initiator Fib_alpha PF08702.10 KFQ94533.1 - 5.7 7.1 10.1 14 5.9 1.2 3.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF4140 PF13600.6 KFQ94533.1 - 6.3 7.3 14.1 4.2 7.9 0.4 4.2 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) NYD-SP28_assoc PF14775.6 KFQ94533.1 - 8 6.6 8.7 36 4.6 0.3 4.0 3 1 0 3 3 3 0 Sperm tail C-terminal domain YabA PF06156.13 KFQ94533.1 - 9.7 6.9 20.4 3.2 8.4 1.7 4.8 3 2 2 5 5 5 0 Initiation control protein YabA Filament PF00038.21 KFQ94534.1 - 9.8e-104 347.3 45.6 1.1e-103 347.1 45.6 1.0 1 0 0 1 1 1 1 Intermediate filament protein DUF1664 PF07889.12 KFQ94534.1 - 0.0042 17.1 23.0 0.17 12.0 0.5 3.9 2 1 2 4 4 4 3 Protein of unknown function (DUF1664) Ribonuclease_T2 PF00445.18 KFQ94534.1 - 0.054 13.7 1.3 0.062 13.5 0.2 1.8 2 0 0 2 2 2 0 Ribonuclease T2 family Spc7 PF08317.11 KFQ94534.1 - 0.25 10.2 35.6 0.17 10.8 11.4 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein YbjQ_1 PF01906.17 KFQ94534.1 - 0.39 11.4 2.0 1.4 9.6 1.8 2.1 1 1 0 1 1 1 0 Putative heavy-metal-binding APG6_N PF17675.1 KFQ94534.1 - 0.4 11.2 46.6 1.6 9.3 7.2 3.3 2 1 1 3 3 3 0 Apg6 coiled-coil region DUF4407 PF14362.6 KFQ94534.1 - 0.55 9.5 27.1 1.6 8.0 3.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF573 PF04504.14 KFQ94534.1 - 0.6 10.8 9.2 0.094 13.4 0.9 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF573 TPR_MLP1_2 PF07926.12 KFQ94534.1 - 2.4 8.2 47.0 0.023 14.8 6.5 3.7 2 2 0 3 3 3 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 KFQ94534.1 - 3.4 6.7 30.7 12 4.9 6.7 2.5 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Syntaxin-6_N PF09177.11 KFQ94534.1 - 9 6.9 28.0 1.1 9.9 2.8 4.5 1 1 1 3 3 3 0 Syntaxin 6, N-terminal KfrA_N PF11740.8 KFQ94534.1 - 9.7 6.9 26.8 4.3 8.0 9.0 3.7 1 1 2 3 3 3 0 Plasmid replication region DNA-binding N-term Jnk-SapK_ap_N PF09744.9 KFQ94534.1 - 9.8 6.4 45.8 0.14 12.4 7.8 4.2 2 2 2 4 4 4 0 JNK_SAPK-associated protein-1 Filament PF00038.21 KFQ94535.1 - 4.4e-117 391.1 35.5 5e-117 390.9 35.5 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.12 KFQ94535.1 - 4.5e-05 23.5 2.0 4.5e-05 23.5 2.0 3.7 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 KFQ94535.1 - 0.00018 20.7 9.1 0.0056 15.8 3.8 2.6 1 1 1 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 KFQ94535.1 - 0.0033 16.8 19.9 0.016 14.6 11.6 2.8 1 1 2 3 3 3 2 Domain of unknown function (DUF4407) APG6_N PF17675.1 KFQ94535.1 - 0.01 16.4 6.3 0.01 16.4 6.3 3.9 2 2 1 4 4 4 0 Apg6 coiled-coil region BRE1 PF08647.11 KFQ94535.1 - 0.018 15.1 2.9 0.018 15.1 2.9 4.1 3 1 1 4 4 4 0 BRE1 E3 ubiquitin ligase SPATA1_C PF15743.5 KFQ94535.1 - 0.024 14.7 0.2 0.024 14.7 0.2 3.9 2 1 0 3 3 3 0 Spermatogenesis-associated C-terminus FlaC_arch PF05377.11 KFQ94535.1 - 0.14 12.5 17.6 1.4 9.3 1.7 4.6 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 KFQ94535.1 - 0.16 12.0 16.2 1.1 9.3 0.9 3.8 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1192 PF06698.11 KFQ94535.1 - 0.17 11.9 6.7 4.6 7.4 1.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Fib_alpha PF08702.10 KFQ94535.1 - 0.22 11.7 22.8 7.7 6.7 1.0 4.2 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family ADIP PF11559.8 KFQ94535.1 - 0.3 11.2 25.3 2.6 8.1 1.7 4.2 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Phage_GP20 PF06810.11 KFQ94535.1 - 0.55 10.0 17.6 0.6 9.9 3.4 3.4 2 2 0 3 3 3 0 Phage minor structural protein GP20 Golgin_A5 PF09787.9 KFQ94535.1 - 0.58 9.6 26.5 5.1 6.5 16.5 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 Spc7 PF08317.11 KFQ94535.1 - 0.77 8.6 26.5 0.14 11.0 12.7 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein FlxA PF14282.6 KFQ94535.1 - 0.92 9.5 17.8 3.3 7.8 0.4 3.0 2 1 1 3 3 3 0 FlxA-like protein DivIC PF04977.15 KFQ94535.1 - 1 9.2 27.9 1.5 8.7 0.8 5.2 5 2 0 5 5 5 0 Septum formation initiator Lebercilin PF15619.6 KFQ94535.1 - 1.1 8.9 30.7 1.4e+02 2.0 26.9 3.9 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CENP-F_leu_zip PF10473.9 KFQ94535.1 - 1.1 9.2 31.8 12 5.9 6.5 4.3 1 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 KFQ94535.1 - 1.1 9.2 16.2 11 6.1 1.4 4.1 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 KFQ94535.1 - 1.3 8.8 18.7 4.2 7.2 1.4 3.5 2 2 1 4 4 4 0 Protein of unknown function (DUF724) Nas2_N PF18265.1 KFQ94535.1 - 1.3 9.0 14.1 1.1 9.2 0.1 4.8 4 1 1 5 5 5 0 Nas2 N_terminal domain DUF4446 PF14584.6 KFQ94535.1 - 1.6 8.7 15.7 5.1 7.1 0.0 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF4446) SlyX PF04102.12 KFQ94535.1 - 1.8 9.3 30.0 0.77 10.4 2.1 5.6 3 1 2 5 5 5 0 SlyX ATG16 PF08614.11 KFQ94535.1 - 3.4 7.8 32.7 8.2 6.6 4.1 4.0 2 2 1 3 3 3 0 Autophagy protein 16 (ATG16) Prefoldin PF02996.17 KFQ94535.1 - 4.2 7.3 18.5 1.1 9.1 1.4 4.2 4 1 0 4 4 4 0 Prefoldin subunit JIP_LZII PF16471.5 KFQ94535.1 - 4.6 7.5 22.6 1.8 8.8 3.4 4.1 4 1 0 4 4 3 0 JNK-interacting protein leucine zipper II Jnk-SapK_ap_N PF09744.9 KFQ94535.1 - 9.4 6.4 28.8 6.7 6.9 6.9 3.6 2 1 2 4 4 4 0 JNK_SAPK-associated protein-1 Snapin_Pallidin PF14712.6 KFQ94535.1 - 9.7 6.7 19.8 0.47 10.9 0.7 4.3 3 1 2 5 5 5 0 Snapin/Pallidin Filament PF00038.21 KFQ94536.1 - 4.8e-114 381.2 24.8 5.4e-114 381.0 24.8 1.0 1 0 0 1 1 1 1 Intermediate filament protein DUF4407 PF14362.6 KFQ94536.1 - 0.0035 16.8 10.6 0.36 10.1 0.2 2.6 1 1 0 2 2 2 2 Domain of unknown function (DUF4407) Sec2p PF06428.11 KFQ94536.1 - 0.047 13.7 0.3 0.047 13.7 0.3 4.7 4 2 1 5 5 5 0 GDP/GTP exchange factor Sec2p DUF1664 PF07889.12 KFQ94536.1 - 0.091 12.8 14.6 3.1 7.9 1.7 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 KFQ94536.1 - 0.11 12.6 0.2 0.11 12.6 0.2 4.0 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.9 KFQ94536.1 - 0.18 12.1 13.6 0.59 10.5 1.1 4.5 3 1 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF5082 PF16888.5 KFQ94536.1 - 0.21 11.9 18.2 0.76 10.1 0.9 4.3 3 1 2 5 5 5 0 Domain of unknown function (DUF5082) SlyX PF04102.12 KFQ94536.1 - 0.27 11.9 23.1 9 7.0 0.4 5.5 4 1 2 6 6 5 0 SlyX DivIC PF04977.15 KFQ94536.1 - 0.33 10.8 17.9 1.9 8.3 1.0 4.6 4 0 0 4 4 4 0 Septum formation initiator Fib_alpha PF08702.10 KFQ94536.1 - 0.65 10.2 14.5 19 5.4 0.7 3.9 2 1 0 4 4 4 0 Fibrinogen alpha/beta chain family DUF2461 PF09365.10 KFQ94536.1 - 0.68 9.9 4.4 21 5.0 0.1 3.2 3 1 0 3 3 3 0 Conserved hypothetical protein (DUF2461) CENP-F_leu_zip PF10473.9 KFQ94536.1 - 1.4 8.9 29.3 2.4 8.2 4.3 4.4 3 2 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 KFQ94536.1 - 1.6 9.2 29.1 0.41 11.2 0.7 3.5 4 0 0 4 4 4 0 Apg6 coiled-coil region Spc7 PF08317.11 KFQ94536.1 - 4.4 6.1 23.9 4.3 6.1 4.5 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein PHA_gran_rgn PF09650.10 KFQ94536.1 - 4.6 7.6 7.9 14 6.0 1.6 3.4 1 1 3 4 4 4 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) DUF4446 PF14584.6 KFQ94536.1 - 7.1 6.6 10.9 2.2 8.3 0.1 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF4446) Lebercilin PF15619.6 KFQ94536.1 - 9.8 5.8 25.3 9.4 5.8 19.1 3.0 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Filament PF00038.21 KFQ94537.1 - 2.2e-100 336.2 39.0 2.5e-100 336.1 39.0 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.12 KFQ94537.1 - 2.1e-05 24.6 4.0 2.1e-05 24.6 4.0 4.2 2 2 2 4 4 4 1 TPR/MLP1/MLP2-like protein EzrA PF06160.12 KFQ94537.1 - 0.0047 15.2 28.3 0.02 13.1 10.6 3.1 2 1 1 3 3 3 2 Septation ring formation regulator, EzrA DUF2312 PF10073.9 KFQ94537.1 - 0.0075 15.9 1.1 0.065 12.9 0.1 2.9 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2312) APG6_N PF17675.1 KFQ94537.1 - 0.014 16.0 5.1 0.014 16.0 5.1 4.0 2 2 2 4 4 4 0 Apg6 coiled-coil region Prefoldin_2 PF01920.20 KFQ94537.1 - 0.016 15.2 32.6 0.63 10.0 0.2 6.0 3 3 3 7 7 7 0 Prefoldin subunit DUF3220 PF11516.8 KFQ94537.1 - 0.041 14.1 0.0 0.14 12.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) DUF4446 PF14584.6 KFQ94537.1 - 0.059 13.4 0.2 0.059 13.4 0.2 4.1 2 1 3 5 5 5 0 Protein of unknown function (DUF4446) BAR_3_WASP_bdg PF10456.9 KFQ94537.1 - 0.061 12.8 5.6 0.097 12.1 0.2 2.4 1 1 0 2 2 2 0 WASP-binding domain of Sorting nexin protein Baculo_PEP_C PF04513.12 KFQ94537.1 - 0.067 13.2 22.6 0.019 15.0 6.6 3.5 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.9 KFQ94537.1 - 0.072 13.1 42.0 0.048 13.7 8.0 4.5 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 T2SSM PF04612.12 KFQ94537.1 - 0.092 12.8 9.9 1.1 9.3 0.1 3.1 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein M ADIP PF11559.8 KFQ94537.1 - 0.15 12.1 36.5 0.24 11.5 1.6 4.1 2 2 2 4 4 4 0 Afadin- and alpha -actinin-Binding Fungal_TACC PF12709.7 KFQ94537.1 - 0.16 12.5 26.2 8.1 7.0 4.7 5.5 3 3 1 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins RNA_binding PF01877.17 KFQ94537.1 - 0.16 12.2 13.7 0.08 13.2 2.8 3.4 2 2 2 4 4 4 0 RNA binding Lectin_N PF03954.14 KFQ94537.1 - 0.22 11.3 16.0 5.1 6.8 6.7 3.7 2 2 1 3 3 3 0 Hepatic lectin, N-terminal domain Spc7 PF08317.11 KFQ94537.1 - 0.27 10.1 38.6 0.048 12.5 11.5 3.3 1 1 1 3 3 3 0 Spc7 kinetochore protein GAS PF13851.6 KFQ94537.1 - 0.51 9.7 34.9 4.6 6.5 16.5 3.8 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding DUF4140 PF13600.6 KFQ94537.1 - 0.62 10.5 20.6 13 6.3 0.8 5.0 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.6 KFQ94537.1 - 0.62 9.4 19.1 12 5.2 7.7 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Nsp1_C PF05064.13 KFQ94537.1 - 0.79 9.5 25.0 0.3 10.9 3.7 3.0 1 1 1 3 3 3 0 Nsp1-like C-terminal region Tropomyosin_1 PF12718.7 KFQ94537.1 - 0.93 9.6 31.5 3.7 7.7 12.2 3.6 1 1 1 3 3 3 0 Tropomyosin like Laminin_II PF06009.12 KFQ94537.1 - 1.3 9.1 21.8 0.52 10.3 7.4 3.6 2 2 1 3 3 3 0 Laminin Domain II OrfB_Zn_ribbon PF07282.11 KFQ94537.1 - 1.5 8.8 4.3 26 4.9 0.1 3.2 4 0 0 4 4 3 0 Putative transposase DNA-binding domain DUF1664 PF07889.12 KFQ94537.1 - 2 8.4 21.7 6.7 6.8 5.5 4.1 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF812 PF05667.11 KFQ94537.1 - 2.2 7.0 30.8 3.7 6.3 8.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Golgin_A5 PF09787.9 KFQ94537.1 - 2.3 7.6 35.8 0.69 9.3 17.9 2.7 1 1 3 4 4 4 0 Golgin subfamily A member 5 DUF4200 PF13863.6 KFQ94537.1 - 3.4 8.1 30.9 1.4 9.3 6.2 4.4 2 2 2 4 4 4 0 Domain of unknown function (DUF4200) Transposase_22 PF02994.14 KFQ94537.1 - 4.3 7.6 6.4 0.47 10.6 1.0 2.2 3 0 0 3 3 2 0 L1 transposable element RBD-like domain ATG16 PF08614.11 KFQ94537.1 - 4.3 7.5 35.8 11 6.2 12.6 3.8 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) SLATT_6 PF18169.1 KFQ94537.1 - 4.9 6.7 9.3 2.8 7.5 2.3 3.0 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 6 Sec2p PF06428.11 KFQ94537.1 - 5.2 7.1 26.3 0.085 12.8 4.6 4.6 3 2 1 4 4 4 0 GDP/GTP exchange factor Sec2p SlyX PF04102.12 KFQ94537.1 - 5.4 7.7 35.3 0.79 10.4 4.8 6.0 2 2 3 6 6 6 0 SlyX Fib_alpha PF08702.10 KFQ94537.1 - 5.7 7.1 31.6 5.5 7.2 0.4 3.8 1 1 1 4 4 4 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 KFQ94537.1 - 6.6 7.1 29.9 23 5.4 10.8 3.2 1 1 1 2 2 1 0 Fez1 ERM PF00769.19 KFQ94537.1 - 8.9 6.0 30.4 1.6 8.5 7.0 2.6 1 1 0 2 2 2 0 Ezrin/radixin/moesin family Phage_GPO PF05929.11 KFQ94537.1 - 9.4 5.8 15.2 1 8.9 5.9 2.8 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF883 PF05957.13 KFQ94537.1 - 9.8 6.9 12.0 6.1 7.5 0.3 4.3 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) Filament PF00038.21 KFQ94538.1 - 3.9e-94 315.7 35.4 4.4e-94 315.6 35.4 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.12 KFQ94538.1 - 5.6e-05 23.2 3.0 5.6e-05 23.2 3.0 4.1 2 2 2 4 4 4 1 TPR/MLP1/MLP2-like protein DUF2312 PF10073.9 KFQ94538.1 - 0.0076 15.9 0.7 0.056 13.1 0.1 2.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2312) EzrA PF06160.12 KFQ94538.1 - 0.0094 14.2 26.6 0.051 11.8 10.2 3.1 1 1 0 3 3 3 3 Septation ring formation regulator, EzrA RNA_binding PF01877.17 KFQ94538.1 - 0.022 15.0 9.2 0.069 13.4 2.5 2.7 2 1 0 2 2 2 0 RNA binding BAR_3_WASP_bdg PF10456.9 KFQ94538.1 - 0.041 13.3 3.6 0.16 11.4 0.1 2.3 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein DUF4446 PF14584.6 KFQ94538.1 - 0.044 13.8 0.2 0.044 13.8 0.2 3.8 2 1 1 4 4 4 0 Protein of unknown function (DUF4446) Prefoldin_2 PF01920.20 KFQ94538.1 - 0.047 13.6 28.8 1.1 9.2 4.5 5.5 3 2 2 5 5 5 0 Prefoldin subunit DUF3220 PF11516.8 KFQ94538.1 - 0.074 13.3 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) Lectin_N PF03954.14 KFQ94538.1 - 0.081 12.7 15.0 6.6 6.5 6.4 3.6 2 2 1 3 3 3 0 Hepatic lectin, N-terminal domain ADIP PF11559.8 KFQ94538.1 - 0.095 12.8 33.3 0.58 10.2 1.9 4.1 2 2 2 4 4 4 0 Afadin- and alpha -actinin-Binding T2SSM PF04612.12 KFQ94538.1 - 0.13 12.3 9.3 1.8 8.6 0.1 3.1 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein M CENP-F_leu_zip PF10473.9 KFQ94538.1 - 0.16 12.0 39.0 0.45 10.5 8.1 4.6 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 KFQ94538.1 - 0.19 12.3 37.8 0.096 13.2 4.0 3.7 2 2 2 4 4 4 0 Apg6 coiled-coil region GAS PF13851.6 KFQ94538.1 - 0.25 10.7 32.7 0.87 8.9 13.8 3.7 2 2 1 3 3 3 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KFQ94538.1 - 0.31 9.9 35.7 0.046 12.6 11.4 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein Lzipper-MIP1 PF14389.6 KFQ94538.1 - 0.35 11.2 24.1 0.38 11.1 6.3 4.3 5 0 0 5 5 4 0 Leucine-zipper of ternary complex factor MIP1 DUF2721 PF11026.8 KFQ94538.1 - 1.1 9.1 3.0 1.1 9.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF45 PF01863.17 KFQ94538.1 - 1.3 9.1 9.9 0.28 11.2 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function DUF45 Fungal_TACC PF12709.7 KFQ94538.1 - 1.5 9.3 25.6 5.2 7.6 3.9 5.4 3 3 0 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins Nsp1_C PF05064.13 KFQ94538.1 - 1.7 8.5 24.0 4.4 7.2 5.9 2.9 1 1 1 2 2 2 0 Nsp1-like C-terminal region SlyX PF04102.12 KFQ94538.1 - 1.9 9.2 34.5 0.79 10.4 4.8 6.0 2 2 3 6 6 6 0 SlyX DUF883 PF05957.13 KFQ94538.1 - 2.2 8.9 10.5 3.3 8.4 0.1 4.1 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) DUF4407 PF14362.6 KFQ94538.1 - 2.6 7.3 17.1 1.1e+03 -1.3 17.1 3.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 KFQ94538.1 - 3 7.9 19.7 4.7 7.3 4.9 4.0 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) OrfB_Zn_ribbon PF07282.11 KFQ94538.1 - 3.2 7.7 5.5 27 4.8 0.1 3.3 4 0 0 4 4 3 0 Putative transposase DNA-binding domain Phage_GPO PF05929.11 KFQ94538.1 - 3.7 7.1 12.2 0.95 9.0 6.2 2.4 1 1 2 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4510 PF14971.6 KFQ94538.1 - 4.1 7.7 9.7 0.18 12.2 1.1 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF4510) Sec2p PF06428.11 KFQ94538.1 - 4.3 7.4 25.8 0.09 12.8 4.6 4.5 3 2 1 4 4 4 0 GDP/GTP exchange factor Sec2p SLATT_6 PF18169.1 KFQ94538.1 - 5 6.7 10.0 3.9 7.1 2.9 3.1 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 6 Golgin_A5 PF09787.9 KFQ94538.1 - 5.5 6.4 34.1 0.31 10.5 16.4 2.8 1 1 2 3 3 3 0 Golgin subfamily A member 5 Tropomyosin_1 PF12718.7 KFQ94538.1 - 5.7 7.1 33.0 3.4 7.8 1.0 3.8 1 1 2 3 3 3 0 Tropomyosin like DivIC PF04977.15 KFQ94538.1 - 6 6.7 31.1 1.1 9.1 1.1 5.7 3 2 3 6 6 6 0 Septum formation initiator Transposase_22 PF02994.14 KFQ94538.1 - 6 7.1 7.2 0.49 10.6 1.0 2.3 3 0 0 3 3 3 0 L1 transposable element RBD-like domain Laminin_II PF06009.12 KFQ94538.1 - 6.2 6.8 20.1 0.5 10.4 7.0 3.4 1 1 1 3 3 3 0 Laminin Domain II SPATA1_C PF15743.5 KFQ94538.1 - 9.9 6.2 28.5 0.58 10.2 5.5 3.5 1 1 1 2 2 1 0 Spermatogenesis-associated C-terminus Filament PF00038.21 KFQ94539.1 - 1.6e-97 326.9 34.3 1.9e-97 326.6 34.3 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.12 KFQ94539.1 - 1.5e-07 31.5 30.7 7.9e-07 29.2 0.2 4.0 3 1 0 4 4 4 2 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 KFQ94539.1 - 0.00021 20.9 27.2 0.0053 16.3 17.9 2.4 1 1 0 2 2 2 2 Golgin subfamily A member 5 Tropomyosin_1 PF12718.7 KFQ94539.1 - 0.00065 19.9 23.5 0.0064 16.7 11.4 3.7 3 1 0 3 3 3 2 Tropomyosin like Phage_GP20 PF06810.11 KFQ94539.1 - 0.0024 17.7 3.4 0.0024 17.7 3.4 3.0 2 2 0 2 2 2 1 Phage minor structural protein GP20 Exonuc_VII_L PF02601.15 KFQ94539.1 - 0.0097 15.5 8.2 0.0097 15.5 8.2 2.2 2 0 0 2 2 2 1 Exonuclease VII, large subunit BAR_3_WASP_bdg PF10456.9 KFQ94539.1 - 0.02 14.3 1.4 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein DUF2551 PF10826.8 KFQ94539.1 - 0.032 14.5 0.2 0.27 11.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2551) DUF4407 PF14362.6 KFQ94539.1 - 0.037 13.4 11.4 4 6.7 11.4 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 KFQ94539.1 - 0.043 12.7 31.0 0.016 14.1 12.2 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein Lectin_N PF03954.14 KFQ94539.1 - 0.046 13.5 14.3 37 4.0 9.7 4.0 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Laminin_II PF06009.12 KFQ94539.1 - 0.078 13.0 15.0 0.062 13.3 6.7 3.1 2 2 1 3 3 3 0 Laminin Domain II Bacillus_HBL PF05791.11 KFQ94539.1 - 0.1 12.4 12.3 0.018 14.8 5.0 3.0 2 2 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Transferrin PF00405.17 KFQ94539.1 - 0.13 11.4 0.1 6 5.9 0.1 2.1 2 0 0 2 2 2 0 Transferrin DUF720 PF05302.11 KFQ94539.1 - 0.14 12.0 8.3 0.082 12.8 5.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF720) Atg14 PF10186.9 KFQ94539.1 - 0.28 10.2 18.0 4.8 6.2 14.3 2.7 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Nop PF01798.18 KFQ94539.1 - 0.35 10.3 7.8 0.17 11.4 0.3 2.2 2 0 0 2 2 2 0 snoRNA binding domain, fibrillarin WEMBL PF05701.11 KFQ94539.1 - 0.43 9.2 20.1 2 7.0 16.6 2.5 1 1 0 2 2 2 0 Weak chloroplast movement under blue light Fungal_TACC PF12709.7 KFQ94539.1 - 0.57 10.7 24.5 1.1 9.8 4.7 5.3 3 2 1 5 5 5 0 Fungal Transforming acidic coiled-coil (TACC) proteins Gp58 PF07902.11 KFQ94539.1 - 0.64 8.2 11.5 1.1 7.5 11.1 1.7 1 1 0 1 1 1 0 gp58-like protein Vps5 PF09325.10 KFQ94539.1 - 0.76 9.3 14.7 0.47 9.9 1.7 3.0 2 1 1 3 3 3 0 Vps5 C terminal like DUF4200 PF13863.6 KFQ94539.1 - 1.1 9.7 24.9 0.81 10.1 0.3 3.6 2 2 0 2 2 2 0 Domain of unknown function (DUF4200) FapA PF03961.13 KFQ94539.1 - 1.2 7.7 23.7 4.2 5.9 0.3 3.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A Cob_adeno_trans PF01923.18 KFQ94539.1 - 1.8 8.7 9.1 0.46 10.6 1.4 2.9 1 1 1 2 2 2 0 Cobalamin adenosyltransferase ADIP PF11559.8 KFQ94539.1 - 2 8.5 28.0 0.8 9.8 11.7 4.4 2 2 2 4 4 4 0 Afadin- and alpha -actinin-Binding Phage_Mu_Gam PF07352.12 KFQ94539.1 - 2.5 8.0 21.7 5.3 6.9 0.1 4.6 3 2 1 4 4 4 0 Bacteriophage Mu Gam like protein POX PF07526.11 KFQ94539.1 - 2.5 8.7 14.0 1.1 9.8 6.1 2.6 2 1 0 2 2 2 0 Associated with HOX BLOC1_2 PF10046.9 KFQ94539.1 - 2.5 8.4 25.0 2.2 8.7 0.1 5.1 3 2 3 6 6 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PspA_IM30 PF04012.12 KFQ94539.1 - 2.7 7.5 21.3 6.6 6.2 2.8 4.2 1 1 2 3 3 3 0 PspA/IM30 family Phage_GPO PF05929.11 KFQ94539.1 - 2.8 7.5 10.0 0.95 9.0 6.3 2.1 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4446 PF14584.6 KFQ94539.1 - 3.1 7.7 19.6 0.65 10.0 0.1 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF4446) DUF948 PF06103.11 KFQ94539.1 - 3.3 8.0 8.3 3.3 8.0 0.5 3.7 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) JIP_LZII PF16471.5 KFQ94539.1 - 3.7 7.8 27.6 2.4 8.4 1.3 5.5 4 1 1 5 5 5 0 JNK-interacting protein leucine zipper II DUF4140 PF13600.6 KFQ94539.1 - 4 7.9 12.4 11 6.5 0.4 4.4 3 2 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF1664 PF07889.12 KFQ94539.1 - 5 7.2 16.5 9.2 6.3 4.4 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 KFQ94539.1 - 5.8 7.0 33.7 3.2 7.8 2.1 3.1 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 KFQ94539.1 - 5.9 6.7 20.3 1.9 8.3 8.2 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF724) MADF_DNA_bdg PF10545.9 KFQ94539.1 - 6.1 7.2 8.2 1.9 8.9 0.1 3.5 2 2 2 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like FliD_C PF07195.12 KFQ94539.1 - 7.1 6.0 15.1 3.5e+02 0.4 15.1 3.2 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Baculo_PEP_C PF04513.12 KFQ94539.1 - 7.5 6.6 17.1 16 5.5 4.4 3.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.21 KFQ94540.1 - 1.8e-96 323.4 39.9 2.1e-96 323.2 39.9 1.0 1 0 0 1 1 1 1 Intermediate filament protein ADIP PF11559.8 KFQ94540.1 - 0.0022 18.1 30.2 0.005 16.9 11.3 3.8 2 2 2 4 4 4 1 Afadin- and alpha -actinin-Binding Phage_GP20 PF06810.11 KFQ94540.1 - 0.0025 17.6 3.6 0.0025 17.6 3.6 3.0 1 1 2 3 3 3 1 Phage minor structural protein GP20 GAS PF13851.6 KFQ94540.1 - 0.004 16.5 36.1 0.19 11.1 17.1 3.6 2 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 KFQ94540.1 - 0.0042 17.1 3.7 0.0042 17.1 3.7 3.7 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein Bacillus_HBL PF05791.11 KFQ94540.1 - 0.0051 16.7 3.8 0.0051 16.7 3.8 3.6 1 1 3 4 4 4 1 Bacillus haemolytic enterotoxin (HBL) DUF720 PF05302.11 KFQ94540.1 - 0.0095 15.8 6.6 0.0095 15.8 6.6 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF720) Vps5 PF09325.10 KFQ94540.1 - 0.013 15.1 4.9 0.013 15.1 4.9 2.7 2 1 1 3 3 3 0 Vps5 C terminal like DUF2551 PF10826.8 KFQ94540.1 - 0.079 13.2 0.1 0.28 11.4 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2551) DUF4407 PF14362.6 KFQ94540.1 - 0.089 12.1 15.9 0.15 11.4 7.2 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) HAD_2 PF13419.6 KFQ94540.1 - 0.18 11.9 12.3 0.1 12.6 0.4 3.0 2 2 1 3 3 3 0 Haloacid dehalogenase-like hydrolase Golgin_A5 PF09787.9 KFQ94540.1 - 0.21 11.0 35.5 0.054 13.0 18.9 2.6 1 1 1 2 2 2 0 Golgin subfamily A member 5 Sulfotransfer_4 PF17784.1 KFQ94540.1 - 0.26 11.1 2.3 8.1 6.2 0.3 2.3 2 0 0 2 2 2 0 Sulfotransferase domain ALIX_LYPXL_bnd PF13949.6 KFQ94540.1 - 0.26 10.5 30.0 0.2 10.9 26.3 2.1 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV AIP3 PF03915.13 KFQ94540.1 - 0.28 10.2 21.9 0.032 13.3 13.3 2.2 1 1 1 2 2 2 0 Actin interacting protein 3 DUF2017 PF09438.10 KFQ94540.1 - 0.3 10.9 6.4 0.11 12.4 3.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF2017) WEMBL PF05701.11 KFQ94540.1 - 0.4 9.3 27.4 0.18 10.5 18.2 2.7 2 1 1 3 3 3 0 Weak chloroplast movement under blue light Gp58 PF07902.11 KFQ94540.1 - 0.56 8.4 14.2 0.85 7.8 14.0 1.4 1 1 0 1 1 1 0 gp58-like protein Transcrip_act PF04949.13 KFQ94540.1 - 0.58 10.0 17.1 0.036 13.9 4.2 2.7 2 1 1 3 3 2 0 Transcriptional activator T2SSM PF04612.12 KFQ94540.1 - 0.71 9.9 12.4 2.9 7.9 0.1 3.0 3 1 0 3 3 3 0 Type II secretion system (T2SS), protein M ACP PF06857.11 KFQ94540.1 - 0.78 10.0 2.8 5.3 7.3 0.3 3.0 2 1 1 3 3 2 0 Malonate decarboxylase delta subunit (MdcD) Tropomyosin_1 PF12718.7 KFQ94540.1 - 0.85 9.8 31.8 0.057 13.6 13.1 3.7 1 1 1 3 3 3 0 Tropomyosin like KIF1B PF12423.8 KFQ94540.1 - 1.4 9.4 4.4 7.2 7.1 4.4 2.3 1 1 0 1 1 1 0 Kinesin protein 1B CENP-F_leu_zip PF10473.9 KFQ94540.1 - 1.5 8.9 44.0 0.51 10.4 9.0 4.8 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lectin_N PF03954.14 KFQ94540.1 - 1.7 8.4 18.4 0.56 9.9 1.1 3.6 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Laminin_II PF06009.12 KFQ94540.1 - 2.5 8.1 19.2 0.28 11.2 7.1 3.2 2 1 1 3 3 3 0 Laminin Domain II DUF812 PF05667.11 KFQ94540.1 - 2.5 6.9 28.3 12 4.7 23.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Phage_GPO PF05929.11 KFQ94540.1 - 2.6 7.6 13.6 1.5 8.4 10.3 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase UPF0242 PF06785.11 KFQ94540.1 - 4.7 7.3 35.6 3.2 7.8 17.4 3.1 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 KFQ94540.1 - 5 5.9 34.7 0.81 8.5 12.6 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein Cob_adeno_trans PF01923.18 KFQ94540.1 - 6.6 6.9 12.1 0.44 10.7 1.4 3.0 1 1 2 3 3 3 0 Cobalamin adenosyltransferase WXG100 PF06013.12 KFQ94540.1 - 6.8 7.0 15.1 0.86 9.9 3.4 4.3 2 2 3 5 5 4 0 Proteins of 100 residues with WXG APG6_N PF17675.1 KFQ94540.1 - 9.6 6.7 43.5 1.5 9.3 18.4 4.0 2 2 1 3 3 3 0 Apg6 coiled-coil region Filament PF00038.21 KFQ94541.1 - 1.3e-103 346.9 25.6 1.4e-103 346.7 25.6 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.12 KFQ94541.1 - 3.1e-05 24.0 0.6 3.1e-05 24.0 0.6 3.7 3 1 0 3 3 3 1 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 KFQ94541.1 - 3.1e-05 24.0 31.1 0.00041 20.4 5.5 4.8 3 2 1 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nsp1_C PF05064.13 KFQ94541.1 - 0.0011 18.8 6.2 0.0011 18.8 6.2 3.4 2 2 1 3 3 3 1 Nsp1-like C-terminal region Prefoldin_2 PF01920.20 KFQ94541.1 - 0.0047 16.8 19.6 0.9 9.5 1.8 4.9 3 1 2 5 5 5 1 Prefoldin subunit SPATA1_C PF15743.5 KFQ94541.1 - 0.0085 16.2 17.2 0.083 13.0 0.1 3.0 2 1 0 2 2 2 1 Spermatogenesis-associated C-terminus ADIP PF11559.8 KFQ94541.1 - 0.0095 16.0 26.7 0.21 11.7 0.9 4.1 3 1 1 4 4 4 1 Afadin- and alpha -actinin-Binding DUF5344 PF17279.2 KFQ94541.1 - 0.022 15.3 9.8 0.39 11.3 3.1 4.0 2 2 2 4 4 4 0 Family of unknown function (DUF5344) RasGAP_C PF03836.15 KFQ94541.1 - 0.042 14.0 14.6 0.51 10.5 0.3 3.1 2 1 1 3 3 3 0 RasGAP C-terminus DUF4200 PF13863.6 KFQ94541.1 - 0.087 13.2 17.0 0.25 11.7 0.4 3.4 2 2 1 3 3 3 0 Domain of unknown function (DUF4200) Baculo_PEP_C PF04513.12 KFQ94541.1 - 0.09 12.8 15.5 1 9.4 1.6 3.4 2 1 2 4 4 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 KFQ94541.1 - 0.17 10.8 27.5 0.059 12.2 14.1 2.9 1 1 0 2 2 2 0 Spc7 kinetochore protein SKA1 PF07160.12 KFQ94541.1 - 0.31 10.9 16.8 0.97 9.2 2.1 3.6 3 1 1 4 4 4 0 Spindle and kinetochore-associated protein 1 DUF4140 PF13600.6 KFQ94541.1 - 0.39 11.2 14.7 2.8 8.5 1.8 3.9 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF745 PF05335.13 KFQ94541.1 - 0.57 9.9 10.6 4.2 7.0 7.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF745) TBCC_N PF16752.5 KFQ94541.1 - 0.97 9.9 8.7 5.3 7.5 2.5 3.0 2 1 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain FlaC_arch PF05377.11 KFQ94541.1 - 1.5 9.3 12.7 7.2 7.1 0.3 4.7 4 2 0 4 4 4 0 Flagella accessory protein C (FlaC) Fungal_TACC PF12709.7 KFQ94541.1 - 1.6 9.3 17.4 4.5 7.8 0.5 4.7 4 2 1 5 5 5 0 Fungal Transforming acidic coiled-coil (TACC) proteins Golgin_A5 PF09787.9 KFQ94541.1 - 1.7 8.1 25.6 1.3 8.5 13.8 2.7 1 1 0 2 2 2 0 Golgin subfamily A member 5 DUF4407 PF14362.6 KFQ94541.1 - 2 7.7 18.2 3.7 6.8 4.8 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) CREPT PF16566.5 KFQ94541.1 - 2 8.6 20.7 0.062 13.5 7.1 3.3 3 2 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Tropomyosin_1 PF12718.7 KFQ94541.1 - 2.4 8.3 23.3 2 8.6 10.3 3.4 3 1 0 3 3 3 0 Tropomyosin like DUF4510 PF14971.6 KFQ94541.1 - 2.4 8.5 8.4 0.29 11.5 1.9 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4510) Bacillus_HBL PF05791.11 KFQ94541.1 - 2.6 7.8 7.6 0.61 9.9 2.4 2.4 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Uso1_p115_C PF04871.13 KFQ94541.1 - 4.3 7.7 19.9 0.22 11.9 6.5 3.0 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region APG6_N PF17675.1 KFQ94541.1 - 4.3 7.9 33.1 0.59 10.7 2.8 4.0 2 2 1 4 4 4 0 Apg6 coiled-coil region TMF_DNA_bd PF12329.8 KFQ94541.1 - 5.7 7.0 12.7 15 5.7 0.2 4.4 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding PI3K_P85_iSH2 PF16454.5 KFQ94541.1 - 6.5 6.3 22.8 1.7 8.2 1.7 3.9 3 1 1 4 4 4 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Jnk-SapK_ap_N PF09744.9 KFQ94541.1 - 7 6.9 29.2 0.41 10.9 2.8 3.5 2 2 1 3 3 3 0 JNK_SAPK-associated protein-1 She9_MDM33 PF05546.11 KFQ94541.1 - 7 6.4 12.4 10 5.9 1.0 3.5 2 2 1 3 3 3 0 She9 / Mdm33 family DUF1664 PF07889.12 KFQ94541.1 - 8.2 6.5 13.2 5.6 7.0 1.3 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) KELK PF15796.5 KFQ94541.1 - 8.2 7.0 15.6 0.11 13.0 4.1 3.3 3 1 0 3 3 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Filament PF00038.21 KFQ94542.1 - 1.4e-106 356.6 24.8 1.5e-106 356.5 24.8 1.0 1 0 0 1 1 1 1 Intermediate filament protein CENP-F_leu_zip PF10473.9 KFQ94542.1 - 2.1e-05 24.6 32.2 0.002 18.1 13.6 4.9 3 2 1 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 KFQ94542.1 - 2.1e-05 24.6 24.8 0.00019 21.5 0.7 3.3 3 1 0 3 3 3 2 TPR/MLP1/MLP2-like protein SPATA1_C PF15743.5 KFQ94542.1 - 0.0011 19.1 17.2 0.083 13.0 0.0 3.0 2 1 0 2 2 2 1 Spermatogenesis-associated C-terminus Nsp1_C PF05064.13 KFQ94542.1 - 0.0025 17.6 7.3 0.0025 17.6 7.3 3.2 2 2 1 3 3 3 1 Nsp1-like C-terminal region MAD PF05557.13 KFQ94542.1 - 0.011 14.1 23.3 0.071 11.5 2.8 2.7 1 1 1 3 3 3 0 Mitotic checkpoint protein KELK PF15796.5 KFQ94542.1 - 0.028 14.9 6.3 0.028 14.9 6.3 3.2 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Spc7 PF08317.11 KFQ94542.1 - 0.032 13.1 25.2 0.046 12.6 14.3 2.6 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF4140 PF13600.6 KFQ94542.1 - 0.038 14.4 15.0 17 5.9 0.1 3.9 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) ADIP PF11559.8 KFQ94542.1 - 0.038 14.1 26.5 0.25 11.4 1.5 4.2 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Prefoldin_2 PF01920.20 KFQ94542.1 - 0.049 13.6 24.1 1.2 9.2 2.7 5.0 4 1 1 5 5 4 0 Prefoldin subunit gp45-slide_C PF09116.10 KFQ94542.1 - 0.13 12.4 0.1 4.1 7.5 0.0 2.4 2 0 0 2 2 2 0 gp45 sliding clamp, C terminal APG6_N PF17675.1 KFQ94542.1 - 0.17 12.4 28.1 0.11 13.0 0.7 3.7 3 1 1 4 4 4 0 Apg6 coiled-coil region DUF4200 PF13863.6 KFQ94542.1 - 0.25 11.7 17.3 0.5 10.8 0.2 3.4 2 2 0 2 2 2 0 Domain of unknown function (DUF4200) DUF4510 PF14971.6 KFQ94542.1 - 0.36 11.2 8.3 0.045 14.1 1.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4510) Tropomyosin_1 PF12718.7 KFQ94542.1 - 0.41 10.8 20.5 2.3 8.3 9.3 3.5 3 1 0 3 3 3 0 Tropomyosin like DUF4407 PF14362.6 KFQ94542.1 - 0.43 9.9 16.7 1.5 8.1 4.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 KFQ94542.1 - 0.46 10.5 13.2 0.26 11.3 4.9 2.8 3 1 0 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5344 PF17279.2 KFQ94542.1 - 0.47 11.1 7.2 18 6.0 2.9 3.4 2 2 1 3 3 3 0 Family of unknown function (DUF5344) Fungal_TACC PF12709.7 KFQ94542.1 - 0.49 10.9 17.4 1.4 9.4 2.7 4.7 4 2 1 5 5 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins Bacillus_HBL PF05791.11 KFQ94542.1 - 0.65 9.8 6.4 0.22 11.3 1.6 2.5 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Sec2p PF06428.11 KFQ94542.1 - 1 9.4 24.5 0.05 13.6 3.6 4.1 3 2 1 4 4 3 0 GDP/GTP exchange factor Sec2p SlyX PF04102.12 KFQ94542.1 - 1 10.0 25.8 0.4 11.3 3.1 4.7 4 1 1 5 5 4 0 SlyX Phage_GP20 PF06810.11 KFQ94542.1 - 1.1 9.1 12.3 6.2 6.6 5.1 3.8 2 2 0 2 2 2 0 Phage minor structural protein GP20 FlxA PF14282.6 KFQ94542.1 - 1.4 8.9 20.8 0.33 11.0 9.9 3.7 2 2 1 3 3 3 0 FlxA-like protein DUF641 PF04859.12 KFQ94542.1 - 1.8 8.9 18.3 1.5 9.2 0.8 3.5 2 2 1 3 3 3 0 Plant protein of unknown function (DUF641) Cortex-I_coil PF09304.10 KFQ94542.1 - 2.1 8.6 17.7 14 6.0 1.3 3.9 3 1 0 3 3 3 0 Cortexillin I, coiled coil DivIC PF04977.15 KFQ94542.1 - 2.2 8.1 20.1 6 6.7 0.2 5.0 5 0 0 5 5 5 0 Septum formation initiator Golgin_A5 PF09787.9 KFQ94542.1 - 2.4 7.5 24.6 3.6 7.0 13.8 2.6 1 1 2 3 3 3 0 Golgin subfamily A member 5 Jnk-SapK_ap_N PF09744.9 KFQ94542.1 - 2.9 8.1 29.3 1.6 8.9 5.6 3.3 2 1 2 4 4 4 0 JNK_SAPK-associated protein-1 DUF745 PF05335.13 KFQ94542.1 - 3 7.5 11.5 16 5.2 7.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Prefoldin PF02996.17 KFQ94542.1 - 4.4 7.3 13.9 6.8 6.6 0.4 4.0 3 1 0 4 4 3 0 Prefoldin subunit Mt_ATP-synt_D PF05873.12 KFQ94542.1 - 4.7 7.0 5.4 3.4 7.5 0.2 2.9 2 2 2 4 4 4 0 ATP synthase D chain, mitochondrial (ATP5H) SKA1 PF07160.12 KFQ94542.1 - 4.8 7.0 16.7 1.7 8.4 1.3 3.3 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 Swi5 PF07061.11 KFQ94542.1 - 5.1 7.3 11.1 4.9 7.3 0.4 4.0 4 0 0 4 4 3 0 Swi5 DHR10 PF18595.1 KFQ94542.1 - 6.4 6.9 27.4 1.6 8.8 2.2 3.3 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain CC2-LZ PF16516.5 KFQ94542.1 - 9.5 6.7 17.5 3.5 8.0 1.1 4.1 3 1 1 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Filament PF00038.21 KFQ94543.1 - 3.1e-98 329.2 21.3 3.5e-98 329.0 21.3 1.0 1 0 0 1 1 1 1 Intermediate filament protein CENP-F_leu_zip PF10473.9 KFQ94543.1 - 0.011 15.7 28.6 0.25 11.4 9.5 4.0 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fungal_TACC PF12709.7 KFQ94543.1 - 0.069 13.6 14.9 6.4 7.3 0.5 4.3 3 1 0 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins NTP_transf_8 PF12281.8 KFQ94543.1 - 0.1 12.6 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase TPR_MLP1_2 PF07926.12 KFQ94543.1 - 0.15 12.1 22.2 4.2 7.5 0.0 3.3 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein PSI_PsaF PF02507.15 KFQ94543.1 - 0.16 11.8 0.5 8.2 6.2 0.4 2.3 2 0 0 2 2 2 0 Photosystem I reaction centre subunit III MitMem_reg PF13012.6 KFQ94543.1 - 0.29 11.6 4.2 1.3 9.5 2.5 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Spectrin PF00435.21 KFQ94543.1 - 0.38 11.3 11.9 0.29 11.7 8.2 2.7 2 1 1 3 3 3 0 Spectrin repeat HR1 PF02185.16 KFQ94543.1 - 0.44 10.7 11.5 4.4 7.5 2.4 3.2 1 1 1 2 2 2 0 Hr1 repeat CREPT PF16566.5 KFQ94543.1 - 0.5 10.5 16.0 1.4 9.1 9.9 3.0 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour SlyX PF04102.12 KFQ94543.1 - 0.84 10.3 20.4 1.8 9.2 3.8 4.8 4 1 2 6 6 5 0 SlyX ADIP PF11559.8 KFQ94543.1 - 1.1 9.3 23.0 18 5.4 2.0 4.2 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Phage_GPO PF05929.11 KFQ94543.1 - 1.2 8.7 7.4 0.95 9.0 5.0 2.1 1 1 2 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Spc7 PF08317.11 KFQ94543.1 - 1.5 7.6 26.0 0.29 10.0 17.8 2.9 2 1 1 3 3 3 0 Spc7 kinetochore protein Mt_ATP-synt_D PF05873.12 KFQ94543.1 - 2 8.2 10.3 0.26 11.1 1.8 2.9 3 1 1 4 4 4 0 ATP synthase D chain, mitochondrial (ATP5H) FlaC_arch PF05377.11 KFQ94543.1 - 3.5 8.1 10.9 27 5.2 4.7 3.4 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 KFQ94543.1 - 8.9 6.4 21.2 5.5 7.0 17.1 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Filament PF00038.21 KFQ94544.1 - 1.3e-118 396.2 28.0 1.4e-118 396.0 28.0 1.0 1 0 0 1 1 1 1 Intermediate filament protein Bacillus_HBL PF05791.11 KFQ94544.1 - 0.014 15.2 1.1 0.014 15.2 1.1 2.7 3 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF4407 PF14362.6 KFQ94544.1 - 0.019 14.3 16.9 0.15 11.4 6.5 3.0 1 1 1 3 3 3 0 Domain of unknown function (DUF4407) FapA PF03961.13 KFQ94544.1 - 0.12 11.0 14.6 0.33 9.5 2.0 2.7 1 1 2 3 3 3 0 Flagellar Assembly Protein A Bap31_Bap29_C PF18035.1 KFQ94544.1 - 0.16 12.0 5.8 0.19 11.7 0.5 3.8 4 0 0 4 4 4 0 Bap31/Bap29 cytoplasmic coiled-coil domain Jnk-SapK_ap_N PF09744.9 KFQ94544.1 - 0.16 12.2 24.7 0.37 11.0 3.3 3.8 3 1 1 4 4 4 0 JNK_SAPK-associated protein-1 SlyX PF04102.12 KFQ94544.1 - 0.18 12.4 25.6 2.8 8.6 0.5 5.5 5 1 1 6 6 6 0 SlyX DUF1664 PF07889.12 KFQ94544.1 - 0.36 10.9 13.4 9.9 6.2 0.4 4.1 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 KFQ94544.1 - 0.46 9.5 15.9 0.57 9.2 1.1 2.6 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DHR10 PF18595.1 KFQ94544.1 - 0.82 9.8 30.3 0.055 13.5 3.1 4.6 3 1 1 4 4 4 0 Designed helical repeat protein 10 domain UPF0242 PF06785.11 KFQ94544.1 - 1 9.4 20.3 1 9.4 9.4 2.5 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TPR_MLP1_2 PF07926.12 KFQ94544.1 - 1.1 9.4 29.6 0.89 9.6 9.6 3.8 3 2 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF5344 PF17279.2 KFQ94544.1 - 1.2 9.8 15.0 1.4 9.5 1.4 4.1 3 1 0 3 3 3 0 Family of unknown function (DUF5344) DUF4446 PF14584.6 KFQ94544.1 - 1.3 9.0 10.4 1.4 8.9 0.1 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF4446) Sec2p PF06428.11 KFQ94544.1 - 1.7 8.7 22.7 0.26 11.3 0.3 4.7 3 2 2 5 5 5 0 GDP/GTP exchange factor Sec2p Fib_alpha PF08702.10 KFQ94544.1 - 2.1 8.5 16.3 21 5.3 2.0 4.1 1 1 1 4 4 4 0 Fibrinogen alpha/beta chain family Lzipper-MIP1 PF14389.6 KFQ94544.1 - 2.8 8.3 16.6 0.16 12.3 0.6 4.5 4 1 1 5 5 5 0 Leucine-zipper of ternary complex factor MIP1 ADIP PF11559.8 KFQ94544.1 - 4 7.5 27.8 1.8 8.6 0.4 4.2 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding FlxA PF14282.6 KFQ94544.1 - 4.4 7.4 16.5 3.3 7.8 0.1 3.4 3 1 2 5 5 5 0 FlxA-like protein Prefoldin PF02996.17 KFQ94544.1 - 4.5 7.2 20.0 5.2 7.0 0.9 5.1 2 1 1 4 4 4 0 Prefoldin subunit Arm PF00514.23 KFQ94545.1 - 1.6e-47 158.2 16.9 1.2e-09 37.9 0.1 11.2 12 0 0 12 12 12 6 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KFQ94545.1 - 4.1e-09 35.9 7.8 0.14 12.5 0.0 7.0 8 0 0 8 8 7 3 HEAT repeat HEAT_EZ PF13513.6 KFQ94545.1 - 1.8e-07 31.5 12.1 1.1 9.8 0.0 8.0 8 1 1 9 9 9 3 HEAT-like repeat HEAT_2 PF13646.6 KFQ94545.1 - 7.4e-07 29.5 11.1 0.0013 19.0 0.6 6.2 4 3 1 6 6 6 1 HEAT repeats Cnd1 PF12717.7 KFQ94545.1 - 1.6e-06 28.3 1.5 0.00091 19.3 0.3 3.8 3 2 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.14 KFQ94545.1 - 2e-06 27.3 1.7 0.055 12.7 0.1 3.6 1 1 0 3 3 3 3 V-ATPase subunit H Adaptin_N PF01602.20 KFQ94545.1 - 1.6e-05 23.7 8.1 0.0015 17.2 1.1 3.0 2 1 0 2 2 2 2 Adaptin N terminal region Atx10homo_assoc PF09759.9 KFQ94545.1 - 0.00019 21.4 2.0 0.017 15.1 0.1 4.6 5 1 1 6 6 6 1 Spinocerebellar ataxia type 10 protein domain RasGEF_N_2 PF14663.6 KFQ94545.1 - 0.00049 20.5 5.1 3.6 8.0 0.2 4.8 4 1 1 5 5 5 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arm_2 PF04826.13 KFQ94545.1 - 0.0021 17.5 4.6 0.97 8.8 0.1 4.8 3 2 2 5 5 5 1 Armadillo-like PUL PF08324.11 KFQ94545.1 - 0.0024 17.2 0.2 0.0024 17.2 0.2 2.2 2 1 0 2 2 2 1 PUL domain DUF3361 PF11841.8 KFQ94545.1 - 0.003 17.5 5.8 0.16 11.9 0.3 4.4 3 2 3 6 6 6 1 Domain of unknown function (DUF3361) RTP1_C1 PF10363.9 KFQ94545.1 - 0.05 13.8 0.5 3.4 7.9 0.0 3.6 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 FKBP_C PF00254.28 KFQ94546.1 - 1.6e-99 326.4 0.0 1.8e-27 95.5 0.0 4.3 4 0 0 4 4 4 4 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_1 PF00036.32 KFQ94546.1 - 1.7e-09 36.5 0.5 0.00075 18.9 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KFQ94546.1 - 3.7e-08 32.5 1.5 0.00065 19.1 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFQ94546.1 - 2.1e-07 31.3 0.2 0.027 14.9 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFQ94546.1 - 3.9e-07 29.5 0.1 0.045 13.7 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KFQ94546.1 - 0.0074 16.1 0.1 0.8 9.6 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair M20_dimer PF07687.14 KFQ94546.1 - 0.17 11.8 0.0 33 4.5 0.0 3.2 4 0 0 4 4 4 0 Peptidase dimerisation domain UMPH-1 PF05822.12 KFQ94547.1 - 2.7e-120 400.5 0.5 3.2e-120 400.2 0.5 1.0 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 KFQ94547.1 - 6e-05 23.5 0.0 0.00013 22.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KFQ94547.1 - 0.12 11.7 0.5 0.61 9.4 0.1 2.2 2 1 0 2 2 2 0 Putative Phosphatase BACK PF07707.15 KFQ94548.1 - 5.7e-28 97.0 3.1 4.4e-27 94.2 1.7 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFQ94548.1 - 4.4e-20 71.2 1.8 6.4e-05 23.1 0.0 4.8 3 1 2 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KFQ94548.1 - 2e-16 59.3 5.9 0.0026 17.3 0.3 5.8 5 1 0 5 5 5 3 Kelch motif BTB PF00651.31 KFQ94548.1 - 1.4e-14 54.2 0.0 6.6e-14 52.1 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.6 KFQ94548.1 - 7.2e-12 45.1 0.0 0.37 10.8 0.0 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KFQ94548.1 - 2.8e-08 33.4 1.8 0.038 14.0 0.1 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 KFQ94548.1 - 1.8e-06 28.1 0.1 0.023 15.0 0.0 4.6 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.6 KFQ94548.1 - 0.095 12.7 1.1 18 5.4 0.0 3.7 3 0 0 3 3 3 0 Kelch motif CesT PF05932.13 KFQ94548.1 - 0.13 12.4 0.0 0.42 10.7 0.0 1.8 2 0 0 2 2 2 0 Tir chaperone protein (CesT) family LVIVD PF08309.11 KFQ94548.1 - 0.34 10.2 1.2 17 4.8 0.3 2.4 2 0 0 2 2 2 0 LVIVD repeat Citrate_bind PF16114.5 KFQ94549.1 - 2.1e-90 301.0 0.1 3.5e-90 300.3 0.1 1.4 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 KFQ94549.1 - 4.2e-23 82.0 0.0 5.1e-20 71.9 0.0 3.0 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 KFQ94549.1 - 2.2e-13 50.3 0.1 5e-13 49.1 0.1 1.7 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 KFQ94549.1 - 6.1e-11 42.9 0.0 1.4e-10 41.7 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 KFQ94549.1 - 2.7e-07 30.4 0.0 5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 KFQ94549.1 - 0.00025 20.8 0.0 0.0027 17.5 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_5 PF13549.6 KFQ94549.1 - 0.046 13.2 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain TPR_12 PF13424.6 KFQ94550.1 - 1.5e-17 63.7 6.3 5.1e-06 26.7 0.1 4.3 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ94550.1 - 5.6e-15 54.2 11.3 0.12 12.5 0.0 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ94550.1 - 1.9e-13 49.6 11.0 0.011 15.5 0.0 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_MalT PF17874.1 KFQ94550.1 - 2e-11 43.9 3.7 4.9e-11 42.6 2.9 1.8 2 0 0 2 2 2 1 MalT-like TPR region TPR_8 PF13181.6 KFQ94550.1 - 2e-10 40.0 15.0 0.16 12.2 0.1 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ94550.1 - 8.2e-08 31.8 10.7 0.048 13.7 0.0 7.0 6 1 1 7 7 6 1 Tetratricopeptide repeat RPN7 PF10602.9 KFQ94550.1 - 9e-05 22.2 0.3 9e-05 22.2 0.3 3.2 3 1 1 4 4 4 1 26S proteasome subunit RPN7 TPR_6 PF13174.6 KFQ94550.1 - 0.00051 20.5 10.3 6.2 7.7 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ94550.1 - 0.0038 17.5 5.5 1.9 9.0 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ94550.1 - 0.014 15.6 6.0 0.57 10.4 0.3 3.8 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KFQ94550.1 - 0.031 15.1 2.4 31 5.7 0.0 4.9 4 2 1 5 5 5 0 Tetratricopeptide repeat FlgT_N PF16548.5 KFQ94550.1 - 0.074 13.6 0.7 0.47 11.0 0.0 2.4 2 0 0 2 2 2 0 Flagellar assembly protein T, N-terminal domain ocr PF08684.10 KFQ94550.1 - 0.14 12.6 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 DNA mimic ocr SMBP PF16785.5 KFQ94550.1 - 0.53 10.5 4.7 2.2 8.5 4.7 2.1 1 1 0 1 1 1 0 Small metal-binding protein TPR_11 PF13414.6 KFQ94550.1 - 1.3 8.7 4.0 79 3.1 0.0 4.3 4 0 0 4 4 4 0 TPR repeat TPR_10 PF13374.6 KFQ94550.1 - 2.8 7.9 8.9 3.3 7.7 0.0 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat CNPase PF05881.12 KFQ94551.1 - 1.1e-114 381.8 0.1 1.6e-114 381.3 0.1 1.2 1 0 0 1 1 1 1 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) Zeta_toxin PF06414.12 KFQ94551.1 - 0.00011 21.5 0.0 0.00018 20.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin 6PF2K PF01591.18 KFQ94551.1 - 0.00016 21.1 0.1 0.3 10.3 0.0 2.2 1 1 0 2 2 2 2 6-phosphofructo-2-kinase AAA_33 PF13671.6 KFQ94551.1 - 0.00019 21.6 0.0 0.00059 20.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KFQ94551.1 - 0.00019 21.4 0.2 0.0015 18.6 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 KFQ94551.1 - 0.00052 20.3 0.3 0.011 16.0 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFQ94551.1 - 0.00075 19.9 0.3 0.0052 17.2 0.2 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KFQ94551.1 - 0.0017 18.3 0.0 0.0033 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 KFQ94551.1 - 0.0023 18.5 0.0 0.0041 17.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter NB-ARC PF00931.22 KFQ94551.1 - 0.0044 16.2 0.5 0.089 12.0 0.5 2.3 1 1 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 KFQ94551.1 - 0.0049 17.4 0.0 0.0094 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFQ94551.1 - 0.0075 16.7 0.0 0.019 15.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CPT PF07931.12 KFQ94551.1 - 0.0081 16.0 0.0 0.02 14.8 0.0 1.5 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_30 PF13604.6 KFQ94551.1 - 0.014 15.2 0.0 0.027 14.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain tRNA_lig_kinase PF08303.11 KFQ94551.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 tRNA ligase kinase domain KTI12 PF08433.10 KFQ94551.1 - 0.014 14.9 0.1 0.022 14.2 0.1 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 KAP_NTPase PF07693.14 KFQ94551.1 - 0.018 14.3 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_17 PF13207.6 KFQ94551.1 - 0.026 15.0 0.0 0.06 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFQ94551.1 - 0.03 14.2 0.1 0.74 9.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 KFQ94551.1 - 0.03 14.2 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TK PF00265.18 KFQ94551.1 - 0.032 14.1 0.2 0.055 13.3 0.2 1.3 1 0 0 1 1 1 0 Thymidine kinase AAA_29 PF13555.6 KFQ94551.1 - 0.052 13.3 0.1 0.18 11.6 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 KFQ94551.1 - 0.06 12.4 0.1 3.7 6.5 0.0 2.1 1 1 1 2 2 2 0 Type II/IV secretion system protein RuvB_N PF05496.12 KFQ94551.1 - 0.065 13.0 0.0 0.61 9.8 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 KFQ94551.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TPR_2 PF07719.17 KFQ94552.1 - 4e-18 64.0 7.0 1.4e-06 28.0 1.6 5.4 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ94552.1 - 1.4e-16 59.5 11.2 6.7e-07 28.9 3.8 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ94552.1 - 6.4e-09 35.4 8.1 2.5e-07 30.3 5.1 3.3 3 1 1 4 4 4 1 TPR repeat TPR_17 PF13431.6 KFQ94552.1 - 8.1e-09 35.3 4.6 9e-06 25.7 0.2 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ94552.1 - 2.7e-08 34.0 4.3 4.7e-06 26.8 1.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ94552.1 - 4.5e-08 33.3 0.2 0.021 15.6 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ94552.1 - 8.6e-07 28.7 5.0 0.001 19.1 0.9 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ94552.1 - 2.3e-06 28.0 1.0 0.038 14.5 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ94552.1 - 3.2e-06 27.7 2.5 0.017 15.7 0.5 3.3 2 1 2 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ94552.1 - 9.8e-05 22.5 7.2 0.057 13.7 2.0 2.6 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KFQ94552.1 - 0.00016 21.7 0.3 0.51 10.5 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ94552.1 - 0.00041 20.1 5.0 0.35 10.8 0.2 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 KFQ94552.1 - 0.0035 17.8 0.2 0.52 11.1 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFQ94552.1 - 0.0057 17.2 5.3 0.11 13.1 0.3 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ94552.1 - 0.0097 15.9 1.5 2 8.6 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.12 KFQ94552.1 - 0.011 15.7 4.4 0.083 12.9 3.8 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KFQ94552.1 - 0.044 14.3 0.8 18 5.8 0.1 2.7 1 1 1 3 3 3 0 Alkyl sulfatase dimerisation TOM20_plant PF06552.12 KFQ94552.1 - 0.12 12.1 0.7 1.9 8.2 0.2 2.2 2 0 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 MIT PF04212.18 KFQ94552.1 - 0.24 11.5 4.7 0.23 11.5 1.8 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 KFQ94552.1 - 0.64 10.1 6.0 9 6.5 0.3 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Ras PF00071.22 KFQ94553.1 - 4.7e-25 88.1 0.2 5.4e-25 87.9 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ94553.1 - 1.7e-10 41.2 0.2 3.7e-10 40.1 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ94553.1 - 1.5e-07 31.0 0.1 1.9e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFQ94553.1 - 2.3e-05 24.0 0.2 0.0033 17.0 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFQ94553.1 - 3.9e-05 23.7 0.0 5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KFQ94553.1 - 0.00078 19.5 0.4 0.002 18.2 0.4 1.9 1 1 0 1 1 1 1 Dynamin family DUF2121 PF09894.9 KFQ94553.1 - 0.0014 18.3 0.2 0.016 14.8 0.0 2.2 2 1 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2121) RsgA_GTPase PF03193.16 KFQ94553.1 - 0.0042 17.0 0.2 3 7.7 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KFQ94553.1 - 0.09 13.2 0.1 0.16 12.4 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain DUF2677 PF10838.8 KFQ94553.1 - 0.11 12.5 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2677) UPF0113 PF03657.13 KFQ94553.1 - 0.11 12.8 0.2 0.49 10.7 0.0 2.0 2 0 0 2 2 2 0 UPF0113 PUA domain zf-met PF12874.7 KFQ94554.1 - 5.5e-09 36.1 0.4 5.5e-09 36.1 0.4 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFQ94554.1 - 2e-05 24.7 0.5 2e-05 24.7 0.5 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Pih1_fungal_CS PF18482.1 KFQ94554.1 - 0.022 15.3 0.5 0.022 15.3 0.5 1.0 1 0 0 1 1 1 0 Fungal Pih1 CS domain zf-U1 PF06220.12 KFQ94554.1 - 0.042 13.6 0.8 0.062 13.1 0.2 1.6 1 1 0 1 1 1 0 U1 zinc finger RIG-I_C-RD PF11648.8 KFQ94555.1 - 1.3e-38 131.8 0.9 1.3e-38 131.8 0.9 1.8 2 0 0 2 2 2 1 C-terminal domain of RIG-I RIG-I_C PF18119.1 KFQ94555.1 - 1.4e-35 122.3 1.4 1.4e-35 122.3 1.4 2.0 2 0 0 2 2 2 1 RIG-I receptor C-terminal domain Helicase_C PF00271.31 KFQ94555.1 - 3.2e-17 62.9 0.0 1.3e-16 60.9 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFQ94555.1 - 1.4e-07 31.7 0.1 3e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFQ94555.1 - 7.8e-06 25.8 0.2 1.9e-05 24.5 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.23 KFQ94555.1 - 0.027 13.2 0.1 0.047 12.4 0.1 1.5 1 0 0 1 1 1 0 SNF2 family N-terminal domain GlnD_UR_UTase PF08335.11 KFQ94555.1 - 0.095 12.8 1.8 0.39 10.8 0.1 2.4 2 0 0 2 2 2 0 GlnD PII-uridylyltransferase TTRAP PF14203.6 KFQ94555.1 - 0.11 12.5 0.1 0.49 10.4 0.1 2.1 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein AAA_11 PF13086.6 KFQ94555.1 - 4.3 7.1 5.8 0.54 10.0 0.4 2.2 3 0 0 3 3 3 0 AAA domain PCAF_N PF06466.11 KFQ94556.1 - 5.7e-105 350.4 2.7 8.3e-105 349.9 2.7 1.3 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain PF00439.25 KFQ94556.1 - 1.6e-22 79.3 0.4 4e-22 78.1 0.4 1.7 1 0 0 1 1 1 1 Bromodomain Ras PF00071.22 KFQ94557.1 - 1.6e-61 206.6 0.5 1.9e-61 206.4 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ94557.1 - 2e-35 121.6 0.0 3.5e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ94557.1 - 5.1e-12 45.6 0.1 6.4e-12 45.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFQ94557.1 - 0.0001 21.7 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFQ94557.1 - 0.00017 21.6 0.0 0.00027 21.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFQ94557.1 - 0.001 19.0 0.4 0.37 10.7 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFQ94557.1 - 0.0034 16.9 0.2 0.01 15.4 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFQ94557.1 - 0.028 14.8 0.1 0.043 14.2 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 KFQ94557.1 - 0.1 12.0 0.1 0.33 10.4 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit BrnT_toxin PF04365.13 KFQ94557.1 - 0.15 12.4 0.1 0.97 9.8 0.0 2.0 2 0 0 2 2 2 0 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system GH3 PF03321.13 KFQ94558.1 - 3.1e-25 89.0 0.0 7.7e-24 84.4 0.0 2.0 1 1 0 1 1 1 1 GH3 auxin-responsive promoter STAT_alpha PF01017.20 KFQ94559.1 - 1.3e-53 181.4 16.2 2.7e-53 180.4 16.2 1.5 1 0 0 1 1 1 1 STAT protein, all-alpha domain STAT_bind PF02864.15 KFQ94559.1 - 4.6e-38 130.8 1.9 8.7e-38 129.9 0.0 2.2 2 0 0 2 2 2 1 STAT protein, DNA binding domain STAT_int PF02865.17 KFQ94559.1 - 5e-38 130.3 7.9 5e-38 130.3 7.9 3.2 3 1 1 4 4 4 1 STAT protein, protein interaction domain SH2 PF00017.24 KFQ94559.1 - 0.086 12.9 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 SH2 domain Syntaxin-6_N PF09177.11 KFQ94559.1 - 0.17 12.5 4.7 0.17 12.4 1.3 2.6 2 1 1 3 3 3 0 Syntaxin 6, N-terminal YojJ PF10372.9 KFQ94559.1 - 0.25 11.5 6.7 1.6 8.9 0.3 2.8 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Fib_alpha PF08702.10 KFQ94559.1 - 0.28 11.3 10.3 0.27 11.4 5.3 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.7 KFQ94559.1 - 0.62 10.2 8.3 0.093 12.9 3.1 2.0 2 0 0 2 2 2 0 Tropomyosin like RecG_N PF17190.4 KFQ94559.1 - 1 10.1 10.1 2 9.2 0.2 3.8 3 1 0 3 3 3 0 RecG N-terminal helical domain MerR-DNA-bind PF09278.11 KFQ94559.1 - 2.8 8.6 13.7 3.6 8.2 0.6 4.0 4 0 0 4 4 4 0 MerR, DNA binding Cep57_CLD PF14073.6 KFQ94559.1 - 3.4 7.6 16.2 6.5 6.7 4.5 3.1 2 1 0 3 3 3 0 Centrosome localisation domain of Cep57 PRKG1_interact PF15898.5 KFQ94559.1 - 3.4 8.6 11.3 0.94 10.4 5.2 2.6 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain eIF3_N PF09440.10 KFQ94559.1 - 3.7 8.0 11.8 2.6 8.5 2.7 3.1 2 1 1 3 3 3 0 eIF3 subunit 6 N terminal domain V_ATPase_I PF01496.19 KFQ94560.1 - 1.6e-284 945.9 2.8 1.9e-284 945.7 2.8 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family NAGLU PF05089.12 KFQ94561.1 - 5.8e-119 396.9 1.3 3.6e-75 253.0 0.0 2.1 2 0 0 2 2 2 2 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 KFQ94561.1 - 7e-31 107.7 0.0 1e-30 107.2 0.0 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain HLH PF00010.26 KFQ94562.1 - 4.8e-15 55.2 0.1 1.3e-14 53.9 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3322 PF11795.8 KFQ94562.1 - 0.053 13.5 0.3 0.16 12.0 0.3 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Tubulin PF00091.25 KFQ94564.1 - 4e-55 187.1 0.0 6.8e-55 186.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFQ94564.1 - 9.2e-47 158.3 0.1 1.9e-46 157.3 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFQ94564.1 - 0.025 14.3 0.2 0.063 13.0 0.0 1.7 2 0 0 2 2 2 0 Tubulin domain Tubulin_2 PF13809.6 KFQ94564.1 - 0.049 12.8 0.0 0.083 12.1 0.0 1.4 1 0 0 1 1 1 0 Tubulin like FERM_M PF00373.18 KFQ94565.1 - 0.00016 22.1 0.0 0.00021 21.7 0.0 1.2 1 0 0 1 1 1 1 FERM central domain ACBP PF00887.19 KFQ94565.1 - 0.0046 17.1 0.0 0.0072 16.5 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein MyTH4 PF00784.17 KFQ94566.1 - 1.5e-26 93.0 0.0 3.3e-26 91.9 0.0 1.6 1 0 0 1 1 1 1 MyTH4 domain RA PF00788.23 KFQ94566.1 - 1.7e-07 31.8 0.0 3.9e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PH PF00169.29 KFQ94566.1 - 2.8e-05 24.5 0.2 4.8e-05 23.8 0.2 1.4 1 0 0 1 1 1 1 PH domain ESCRT-II PF05871.12 KFQ94567.1 - 4.8e-23 82.0 0.2 7.4e-23 81.4 0.2 1.3 1 0 0 1 1 1 1 ESCRT-II complex subunit LisH_TPL PF17814.1 KFQ94567.1 - 0.017 14.8 0.5 4.2 7.1 0.5 2.2 2 0 0 2 2 2 0 LisH-like dimerisation domain Cyclin_N PF00134.23 KFQ94568.1 - 1.7e-05 24.5 1.5 0.0022 17.7 0.2 2.7 3 0 0 3 3 3 2 Cyclin, N-terminal domain APG6 PF04111.12 KFQ94569.1 - 1.1e-76 256.8 0.0 1.7e-76 256.2 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KFQ94569.1 - 3.3e-29 102.1 34.1 5.5e-29 101.4 34.1 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region BH3 PF15285.6 KFQ94569.1 - 1.1e-14 53.8 0.7 5.3e-06 26.1 0.5 2.3 2 0 0 2 2 2 2 Beclin-1 BH3 domain, Bcl-2-interacting FapA PF03961.13 KFQ94569.1 - 0.061 11.9 14.8 0.077 11.6 14.1 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 KFQ94569.1 - 0.087 12.4 5.0 0.13 11.8 5.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit IFT57 PF10498.9 KFQ94569.1 - 0.087 11.8 17.0 0.15 11.0 17.0 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Peptidase_S49 PF01343.18 KFQ94569.1 - 0.21 11.5 0.8 0.83 9.6 0.5 2.0 2 0 0 2 2 2 0 Peptidase family S49 MT PF12777.7 KFQ94569.1 - 0.29 10.1 8.7 0.54 9.2 8.7 1.4 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor ERM PF00769.19 KFQ94569.1 - 0.39 10.5 23.0 0.71 9.6 23.0 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Jnk-SapK_ap_N PF09744.9 KFQ94569.1 - 1.2 9.3 22.7 2.5 8.3 22.7 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 V_ATPase_I PF01496.19 KFQ94569.1 - 1.6 6.6 9.6 2.1 6.1 9.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SecA_DEAD PF07517.14 KFQ94569.1 - 1.9 7.7 5.6 2.8 7.2 5.6 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain TMPIT PF07851.13 KFQ94569.1 - 2.7 7.1 11.1 5.4 6.2 11.1 1.6 1 0 0 1 1 1 0 TMPIT-like protein Golgin_A5 PF09787.9 KFQ94569.1 - 3.9 6.9 20.1 6.7 6.1 20.1 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Spc7 PF08317.11 KFQ94569.1 - 3.9 6.2 21.2 8.1 5.2 21.2 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 KFQ94569.1 - 4.8 7.3 21.5 8.5 6.4 21.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GAS PF13851.6 KFQ94569.1 - 6.1 6.1 27.5 35 3.7 27.0 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Syntaxin-6_N PF09177.11 KFQ94569.1 - 8.7 7.0 13.8 11 6.6 8.5 2.7 2 1 1 3 3 2 0 Syntaxin 6, N-terminal PA28_beta PF02252.18 KFQ94570.1 - 4.8e-65 217.7 3.4 6.2e-65 217.3 3.4 1.1 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 KFQ94570.1 - 4e-24 84.4 0.6 9.2e-24 83.3 0.6 1.7 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit TMF_TATA_bd PF12325.8 KFQ94570.1 - 0.12 12.6 1.7 0.2 11.9 0.3 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Cu_amine_oxid PF01179.20 KFQ94571.1 - 8e-124 413.7 0.5 1.1e-123 413.3 0.5 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KFQ94571.1 - 2e-15 57.0 0.0 3.8e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain DUF1965 PF09248.10 KFQ94571.1 - 7.1e-06 25.7 0.4 9.5e-05 22.1 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1965) Cu_amine_oxid PF01179.20 KFQ94572.1 - 1.5e-126 422.6 0.0 1.8e-126 422.4 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KFQ94572.1 - 7.5e-15 55.2 0.0 1.3e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain bMG6 PF17962.1 KFQ94572.1 - 0.055 13.6 0.1 0.32 11.2 0.0 2.1 1 1 1 2 2 2 0 Bacterial macroglobulin domain 6 DUF1965 PF09248.10 KFQ94572.1 - 0.087 12.6 0.0 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1965) PAP2 PF01569.21 KFQ94573.1 - 1.8e-18 66.6 6.8 2.4e-18 66.2 5.5 1.9 1 1 0 1 1 1 1 PAP2 superfamily Sulfate_transp PF00916.20 KFQ94573.1 - 0.00068 18.5 0.8 0.00093 18.0 0.8 1.2 1 0 0 1 1 1 1 Sulfate permease family PspC PF04024.12 KFQ94573.1 - 0.049 13.5 0.1 30 4.5 0.0 3.4 3 1 0 3 3 3 0 PspC domain tRNA_SAD PF07973.14 KFQ94574.1 - 1.5e-09 37.7 0.2 4.4e-09 36.3 0.2 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Nod_GRP PF07806.11 KFQ94574.1 - 0.099 12.5 2.3 0.25 11.2 2.3 1.6 1 0 0 1 1 1 0 Nodule-specific GRP repeat RUN PF02759.19 KFQ94575.1 - 2.9e-34 117.9 0.0 4.9e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 RUN domain FliD_C PF07195.12 KFQ94575.1 - 0.96 8.8 3.0 13 5.1 2.6 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Ribosomal_L27e PF01777.18 KFQ94576.1 - 1.7e-39 134.0 8.8 2e-39 133.8 8.8 1.0 1 0 0 1 1 1 1 Ribosomal L27e protein family NID PF07292.13 KFQ94577.1 - 1.3e-54 182.7 0.0 6.8e-27 93.9 0.1 2.2 2 0 0 2 2 2 2 Nmi/IFP 35 domain (NID) PHM7_cyt PF14703.6 KFQ94577.1 - 0.12 12.6 0.0 2.8 8.2 0.0 2.5 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Ras PF00071.22 KFQ94578.1 - 1.2e-18 67.2 0.0 2e-18 66.5 0.0 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFQ94578.1 - 3.3e-05 24.1 0.0 5.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase N_BRCA1_IG PF16158.5 KFQ94579.1 - 2.2e-31 108.6 0.9 6.8e-31 107.0 0.3 2.2 2 0 0 2 2 2 1 Ig-like domain from next to BRCA1 gene PB1 PF00564.24 KFQ94579.1 - 4.1e-11 42.7 0.2 8e-11 41.7 0.2 1.5 1 0 0 1 1 1 1 PB1 domain ZZ PF00569.17 KFQ94579.1 - 6e-06 26.0 5.0 1.5e-05 24.7 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type DUF2681 PF10883.8 KFQ94579.1 - 0.74 10.3 5.0 2.3 8.7 5.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF4230 PF14014.6 KFQ94579.1 - 0.93 9.7 4.6 5 7.4 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4230) C1_2 PF03107.16 KFQ94579.1 - 0.94 9.8 8.0 0.33 11.3 4.4 2.1 3 0 0 3 3 3 0 C1 domain HIP1_clath_bdg PF16515.5 KFQ94579.1 - 6.3 7.5 13.0 1.5 9.5 3.9 3.0 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1356 PF07092.12 KFQ94580.1 - 1e-100 335.8 4.4 1.2e-100 335.6 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) Anti-TRAP PF15777.5 KFQ94580.1 - 0.0023 17.9 0.1 0.0044 16.9 0.1 1.4 1 0 0 1 1 1 1 Tryptophan RNA-binding attenuator protein inhibitory protein DnaJ_CXXCXGXG PF00684.19 KFQ94580.1 - 0.061 13.7 0.9 0.094 13.1 0.1 1.7 2 0 0 2 2 2 0 DnaJ central domain OB_NTP_bind PF07717.16 KFQ94581.1 - 3.3e-26 91.5 0.0 6.8e-26 90.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KFQ94581.1 - 2.5e-25 88.9 0.1 4.6e-25 88.0 0.1 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFQ94581.1 - 6e-14 52.3 0.0 1.5e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFQ94581.1 - 4.7e-05 23.2 0.1 0.00021 21.1 0.2 2.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFQ94581.1 - 0.0056 17.0 1.1 0.032 14.5 0.9 2.3 2 1 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 KFQ94581.1 - 0.028 14.4 0.1 0.06 13.3 0.1 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 KFQ94581.1 - 0.057 13.3 0.0 0.84 9.5 0.0 2.6 2 1 1 3 3 3 0 Helicase AAA_19 PF13245.6 KFQ94581.1 - 0.13 12.6 0.1 0.31 11.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain ETS_PEA3_N PF04621.13 KFQ94582.1 - 9.3e-100 334.9 24.1 2.9e-99 333.2 24.1 1.7 1 1 0 1 1 1 1 PEA3 subfamily ETS-domain transcription factor N terminal domain Ets PF00178.22 KFQ94582.1 - 7.8e-39 132.0 0.1 1.3e-38 131.3 0.1 1.4 1 0 0 1 1 1 1 Ets-domain Homeodomain PF00046.29 KFQ94583.1 - 8.8e-24 83.1 8.0 1.1e-23 82.9 8.0 1.1 1 0 0 1 1 1 1 Homeodomain Alpha-2-MRAP_C PF06401.11 KFQ94583.1 - 0.025 14.5 1.4 0.027 14.4 1.4 1.3 1 1 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain Homeobox_KN PF05920.11 KFQ94583.1 - 0.053 13.4 0.7 0.12 12.3 0.1 1.8 2 0 0 2 2 2 0 Homeobox KN domain HSM3_C PF18794.1 KFQ94583.1 - 0.13 11.8 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 DNA mismatch repair protein HSM3, C terminal domain Sclerostin PF05463.11 KFQ94584.1 - 4.2e-70 235.5 7.1 4.6e-70 235.4 7.1 1.0 1 0 0 1 1 1 1 Sclerostin (SOST) DAN PF03045.15 KFQ94584.1 - 2.8e-24 85.3 3.6 3.7e-24 84.9 3.6 1.2 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.22 KFQ94584.1 - 4.3e-05 23.8 5.2 8.3e-05 22.8 5.2 1.5 1 1 0 1 1 1 1 Cystine-knot domain DSPc PF00782.20 KFQ94585.1 - 3.9e-34 117.3 0.1 4.7e-34 117.1 0.1 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFQ94585.1 - 4.1e-05 23.3 0.0 5.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KFQ94585.1 - 0.00034 20.9 0.0 0.00044 20.5 0.0 1.2 1 0 0 1 1 1 1 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 KFQ94585.1 - 0.00089 19.4 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate baeRF_family7 PF18849.1 KFQ94585.1 - 0.0095 16.1 0.1 0.013 15.7 0.1 1.1 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 7 DUF442 PF04273.13 KFQ94585.1 - 0.019 15.1 0.0 0.081 13.0 0.0 1.8 2 0 0 2 2 2 0 Putative phosphatase (DUF442) SNase PF00565.17 KFQ94585.1 - 0.049 14.1 0.1 0.21 12.1 0.1 1.9 1 1 0 1 1 1 0 Staphylococcal nuclease homologue baeRF_family6 PF18848.1 KFQ94585.1 - 0.12 12.8 0.1 0.16 12.3 0.1 1.2 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 6 Ras PF00071.22 KFQ94586.1 - 6.5e-58 194.9 0.1 2.1e-57 193.2 0.0 1.7 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KFQ94586.1 - 3.4e-35 120.8 0.1 6.3e-35 120.0 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ94586.1 - 1.7e-17 63.4 0.0 2e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFQ94586.1 - 1.8e-05 24.8 0.0 3.6e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFQ94586.1 - 0.00013 21.4 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFQ94586.1 - 0.0017 17.9 0.0 0.0047 16.5 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFQ94586.1 - 0.0063 16.9 0.0 0.009 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFQ94586.1 - 0.0091 15.9 0.2 2 8.3 0.0 2.5 2 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KFQ94586.1 - 0.035 13.5 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Guanylate_kin PF00625.21 KFQ94587.1 - 1.6e-42 145.2 0.7 3e-42 144.4 0.7 1.4 1 0 0 1 1 1 1 Guanylate kinase L27 PF02828.16 KFQ94587.1 - 7.9e-25 86.4 4.4 5.6e-13 48.4 0.5 2.7 2 0 0 2 2 2 2 L27 domain PDZ PF00595.24 KFQ94587.1 - 2.4e-11 43.8 0.8 4.9e-11 42.8 0.8 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFQ94587.1 - 8.9e-09 35.1 0.6 2.3e-08 33.8 0.2 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KFQ94587.1 - 1.9e-05 24.9 0.1 6.9e-05 23.1 0.1 1.9 1 0 0 1 1 1 1 PDZ domain SH3_2 PF07653.17 KFQ94587.1 - 0.0066 16.1 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFQ94587.1 - 0.01 15.4 0.0 0.023 14.3 0.0 1.6 1 0 0 1 1 1 0 SH3 domain NPBW PF15180.6 KFQ94587.1 - 0.018 14.9 0.2 8.4 6.3 0.0 3.1 3 0 0 3 3 3 0 Neuropeptides B and W IRK_C PF17655.1 KFQ94588.1 - 6.1e-72 240.9 0.0 7.5e-72 240.6 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFQ94588.1 - 2e-35 121.6 0.2 2.9e-35 121.2 0.2 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 KFQ94588.1 - 0.0046 16.9 0.7 0.009 16.0 0.7 1.6 1 0 0 1 1 1 1 Ion channel Pkinase PF00069.25 KFQ94589.1 - 7.5e-69 232.0 0.0 1.1e-68 231.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ94589.1 - 7.7e-41 140.1 0.0 1.1e-40 139.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.24 KFQ94589.1 - 2.5e-11 43.4 0.1 5.8e-11 42.2 0.1 1.7 1 0 0 1 1 1 1 PB1 domain Kinase-like PF14531.6 KFQ94589.1 - 2.8e-06 26.9 0.0 0.00029 20.3 0.0 2.4 1 1 1 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 KFQ94589.1 - 0.029 13.4 0.2 2 7.4 0.0 2.1 2 0 0 2 2 2 0 Seadornavirus VP7 DUF2340 PF10209.9 KFQ94589.1 - 0.052 14.0 0.2 0.11 13.0 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) FTA2 PF13095.6 KFQ94589.1 - 0.058 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Ion_trans PF00520.31 KFQ94591.1 - 4.9e-37 127.5 6.5 6.8e-37 127.0 6.5 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KFQ94591.1 - 1.1e-12 47.8 0.0 2.4e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KFQ94591.1 - 1.2e-11 44.4 0.1 1.2e-11 44.4 0.1 2.0 2 0 0 2 2 2 1 Ion channel DegS PF05384.11 KFQ94591.1 - 0.075 12.5 0.0 0.89 9.0 0.0 2.5 3 0 0 3 3 3 0 Sensor protein DegS Cytochrom_B561 PF03188.16 KFQ94592.1 - 3.9e-43 146.9 10.0 8.7e-43 145.7 10.0 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 BaxI_1 PF12811.7 KFQ94592.1 - 0.0084 15.7 3.6 0.15 11.6 0.6 2.5 1 1 1 2 2 2 2 Bax inhibitor 1 like DUF4293 PF14126.6 KFQ94592.1 - 0.52 10.6 4.2 8 6.7 0.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) DUF2627 PF11118.8 KFQ94592.1 - 0.6 10.7 9.4 1.9 9.1 1.0 3.5 2 2 2 4 4 4 0 Protein of unknown function (DUF2627) GPI2 PF06432.11 KFQ94592.1 - 1.2 8.5 4.4 3.5 7.0 1.4 2.1 1 1 1 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF202 PF02656.15 KFQ94592.1 - 8.3 6.9 17.5 1.6 9.3 2.0 3.9 2 2 2 4 4 4 0 Domain of unknown function (DUF202) Ank_2 PF12796.7 KFQ94593.1 - 6.1e-55 183.8 4.5 1.4e-13 51.3 0.0 5.9 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ94593.1 - 1.4e-45 153.0 1.8 5e-09 36.5 0.0 7.3 2 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ94593.1 - 3.6e-37 122.1 0.5 0.0045 17.4 0.0 10.8 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 KFQ94593.1 - 1.9e-35 120.5 4.4 7.4e-09 35.7 0.0 9.1 3 2 7 10 10 10 9 Ankyrin repeats (many copies) Ank PF00023.30 KFQ94593.1 - 1.6e-33 113.7 6.9 0.00041 20.7 0.0 10.9 11 0 0 11 11 11 5 Ankyrin repeat TPR_2 PF07719.17 KFQ94593.1 - 4.7e-11 41.9 6.8 0.0011 18.9 1.3 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ94593.1 - 4.6e-09 35.8 5.2 0.016 14.9 0.1 3.4 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.28 KFQ94593.1 - 1.1e-07 31.3 8.2 0.00051 19.7 1.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ94593.1 - 1.9e-07 30.8 1.1 0.022 15.0 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFQ94593.1 - 1.2e-06 28.5 0.2 1.4e-05 25.1 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ94593.1 - 1.6e-05 25.3 1.1 6.8e-05 23.4 0.4 2.6 2 1 0 2 2 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ94593.1 - 0.00023 21.6 2.2 0.0096 16.4 0.6 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ94593.1 - 0.00059 20.1 2.9 0.044 14.1 0.1 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat AAA_16 PF13191.6 KFQ94593.1 - 0.0042 17.5 2.8 0.0051 17.2 0.0 2.7 3 1 0 3 3 2 1 AAA ATPase domain TPR_16 PF13432.6 KFQ94593.1 - 0.0045 17.6 3.2 1.1 9.9 0.1 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ94593.1 - 0.056 13.5 0.4 0.88 9.7 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ94593.1 - 0.069 13.6 2.3 0.42 11.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat SUIM_assoc PF16619.5 KFQ94593.1 - 0.66 10.1 8.7 0.41 10.8 5.0 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TPR_6 PF13174.6 KFQ94593.1 - 1.4 9.7 6.0 19 6.2 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_23 PF13489.6 KFQ94595.1 - 1.2e-16 61.0 0.2 1.9e-16 60.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFQ94595.1 - 6e-15 55.8 0.0 1.4e-14 54.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFQ94595.1 - 8.5e-15 55.2 0.0 2.6e-14 53.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFQ94595.1 - 1.4e-12 48.1 0.0 2.9e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFQ94595.1 - 2.2e-10 40.5 0.2 4.2e-10 39.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFQ94595.1 - 5.5e-07 29.2 0.0 3.7e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KFQ94595.1 - 0.00058 19.4 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 KFQ94595.1 - 0.0081 16.0 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase TPMT PF05724.11 KFQ94595.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) CheR PF01739.18 KFQ94595.1 - 0.04 13.4 0.0 1.4 8.4 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain PrmA PF06325.13 KFQ94595.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Eno-Rase_FAD_bd PF07055.12 KFQ94595.1 - 0.15 12.5 1.9 0.18 12.2 0.5 1.8 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain Integrin_beta PF00362.18 KFQ94596.1 - 7.1e-112 373.1 0.0 1.1e-111 372.4 0.0 1.3 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_B_tail PF07965.12 KFQ94596.1 - 3.5e-22 78.7 9.1 3.5e-22 78.7 9.1 4.6 4 1 1 5 5 5 1 Integrin beta tail domain I-EGF_1 PF18372.1 KFQ94596.1 - 9.4e-13 48.0 10.8 9.4e-13 48.0 10.8 6.0 7 0 0 7 7 7 4 Integrin beta epidermal growth factor like domain 1 PSI_integrin PF17205.3 KFQ94596.1 - 1.1e-12 47.4 7.2 1.1e-12 47.4 7.2 5.2 5 1 0 5 5 5 1 Integrin plexin domain EGF_2 PF07974.13 KFQ94596.1 - 5e-12 46.0 98.1 8.5e-06 26.0 16.9 6.4 5 2 2 7 7 7 4 EGF-like domain Integrin_b_cyt PF08725.11 KFQ94596.1 - 7.7e-09 35.1 0.9 7.7e-09 35.1 0.9 2.1 3 0 0 3 3 3 1 Integrin beta cytoplasmic domain RNA_pol_A_CTD PF03118.15 KFQ94596.1 - 0.02 14.6 0.3 0.069 12.9 0.2 1.8 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain Tmemb_9 PF05434.11 KFQ94597.1 - 0.048 13.6 0.1 0.061 13.2 0.1 1.1 1 0 0 1 1 1 0 TMEM9 DUF1072 PF06380.11 KFQ94597.1 - 0.056 13.3 6.7 0.43 10.5 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) Phospholamban PF04272.14 KFQ94600.1 - 4.3e-33 112.5 8.5 4.7e-33 112.4 8.5 1.0 1 0 0 1 1 1 1 Phospholamban Sarcolipin PF05366.11 KFQ94600.1 - 0.0063 16.2 4.5 0.01 15.5 4.5 1.4 1 0 0 1 1 1 1 Sarcolipin Anoctamin PF04547.12 KFQ94600.1 - 0.12 11.2 0.6 0.11 11.3 0.6 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel SLC35F PF06027.12 KFQ94601.1 - 1e-120 402.8 19.3 1.2e-120 402.6 19.3 1.0 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 KFQ94601.1 - 1.9e-14 54.0 24.5 3.1e-09 37.1 11.2 2.0 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 KFQ94601.1 - 2.6e-09 36.5 7.7 2.6e-09 36.5 7.7 1.9 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Mg_trans_NIPA PF05653.14 KFQ94601.1 - 0.001 18.3 2.8 0.001 18.3 2.8 1.9 1 1 0 1 1 1 1 Magnesium transporter NIPA DUF809 PF05663.11 KFQ94601.1 - 0.12 12.5 0.1 0.12 12.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF809) HCO3_cotransp PF00955.21 KFQ94604.1 - 7e-247 820.2 5.1 8.7e-247 819.9 5.1 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 KFQ94604.1 - 1.1e-105 353.3 0.0 1.5e-105 352.8 0.0 1.2 1 0 0 1 1 1 1 Band 3 cytoplasmic domain Hormone_2 PF00123.20 KFQ94605.1 - 7e-46 153.7 3.7 4.9e-15 55.1 0.1 3.3 3 0 0 3 3 3 3 Peptide hormone Lipoprotein_10 PF03202.13 KFQ94605.1 - 0.00029 21.3 3.6 3.3 8.2 0.3 3.7 3 1 1 4 4 4 2 Putative mycoplasma lipoprotein, C-terminal region SBP_bac_8 PF13416.6 KFQ94605.1 - 0.0054 16.6 0.1 6.1 6.6 0.0 3.0 3 0 0 3 3 3 2 Bacterial extracellular solute-binding protein Sa_NUDIX PF18167.1 KFQ94605.1 - 0.13 12.0 2.1 6.8 6.4 0.3 2.7 1 1 2 3 3 3 0 SMODS-associated NUDIX domain MPM1 PF17234.2 KFQ94605.1 - 0.43 10.8 5.4 0.88 9.8 5.5 1.7 1 1 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 DPPIV_N PF00930.21 KFQ94606.1 - 1.5e-98 329.9 8.3 2.4e-98 329.2 8.3 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KFQ94606.1 - 1.6e-56 191.1 1.0 2.5e-56 190.5 1.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_rep PF18811.1 KFQ94606.1 - 1.1e-07 31.6 0.4 2.1e-07 30.7 0.4 1.5 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) low complexity region Esterase_phd PF10503.9 KFQ94606.1 - 0.00012 21.6 0.0 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase LIP PF03583.14 KFQ94606.1 - 0.00041 19.8 0.2 0.00093 18.6 0.2 1.5 1 0 0 1 1 1 1 Secretory lipase Peptidase_S15 PF02129.18 KFQ94606.1 - 0.001 18.7 3.7 0.003 17.2 0.3 2.3 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 KFQ94606.1 - 0.0013 18.4 0.6 0.0041 16.7 0.1 2.0 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KFQ94606.1 - 0.0037 17.9 0.0 0.0088 16.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KFQ94606.1 - 0.0092 15.8 0.8 1.4 8.7 0.3 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.13 KFQ94606.1 - 0.011 14.3 0.0 0.6 8.6 0.0 2.4 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 KFQ94606.1 - 0.014 14.6 0.3 5 6.3 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 FSH1 PF03959.13 KFQ94606.1 - 0.026 14.2 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) AXE1 PF05448.12 KFQ94606.1 - 0.033 12.9 0.0 0.09 11.4 0.0 1.6 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) Prot_inhib_II PF02428.15 KFQ94606.1 - 0.15 12.5 1.5 0.3 11.6 1.5 1.5 1 0 0 1 1 1 0 Potato type II proteinase inhibitor family Ion_trans PF00520.31 KFQ94607.1 - 2.6e-37 128.4 4.7 3.5e-37 127.9 4.7 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KFQ94607.1 - 1.6e-12 47.3 0.0 2.9e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KFQ94607.1 - 1.1e-11 44.5 0.0 1.1e-11 44.5 0.0 2.0 2 0 0 2 2 2 1 Ion channel AAA PF00004.29 KFQ94608.1 - 1.6e-24 86.8 0.0 2.7e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KFQ94608.1 - 4.5e-07 29.8 0.0 1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 KFQ94608.1 - 6.8e-05 22.6 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KFQ94608.1 - 8.9e-05 22.5 0.0 0.00022 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFQ94608.1 - 0.0034 17.8 0.0 0.009 16.4 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KFQ94608.1 - 0.024 14.4 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFQ94608.1 - 0.038 14.3 0.1 0.076 13.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 KFQ94608.1 - 0.16 11.2 0.2 0.29 10.3 0.0 1.4 2 0 0 2 2 2 0 TIP49 P-loop domain BPS PF08947.10 KFQ94609.1 - 4.4e-29 100.0 0.5 1.5e-28 98.4 0.5 1.9 1 0 0 1 1 1 1 BPS (Between PH and SH2) SH2 PF00017.24 KFQ94609.1 - 1.2e-16 60.6 0.1 2.7e-16 59.4 0.1 1.7 1 0 0 1 1 1 1 SH2 domain RA PF00788.23 KFQ94609.1 - 4.7e-14 52.8 0.2 1.5e-13 51.1 0.2 1.9 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain PH PF00169.29 KFQ94609.1 - 5.9e-10 39.6 0.2 2.2e-09 37.8 0.1 2.1 2 0 0 2 2 2 1 PH domain GlgS PF08971.11 KFQ94609.1 - 0.3 11.1 1.4 24 5.0 0.4 2.5 2 0 0 2 2 2 0 Glycogen synthesis protein Cobl PF09469.10 KFQ94610.1 - 4.5e-43 145.5 0.3 1.5e-42 143.8 0.3 1.9 1 0 0 1 1 1 1 Cordon-bleu ubiquitin-like domain RBD PF02196.15 KFQ94610.1 - 5.9e-07 29.5 0.2 0.047 13.8 0.1 2.6 2 0 0 2 2 2 2 Raf-like Ras-binding domain TUG-UBL1 PF11470.8 KFQ94610.1 - 0.065 13.5 0.3 0.44 10.8 0.1 2.4 2 0 0 2 2 2 0 TUG ubiquitin-like domain Aa_trans PF01490.18 KFQ94611.1 - 1.7e-63 214.8 32.2 1.9e-63 214.6 32.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KFQ94611.1 - 0.0001 21.5 17.0 0.0001 21.5 17.0 2.2 1 1 2 3 3 3 1 Tryptophan/tyrosine permease family DUF2427 PF10348.9 KFQ94611.1 - 0.24 11.2 17.9 0.15 11.8 2.2 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF2427) Neurensin PF14927.6 KFQ94611.1 - 1 9.1 0.0 1 9.1 0.0 3.0 4 0 0 4 4 4 0 Neurensin JSRP PF15312.6 KFQ94611.1 - 2.2 8.2 4.0 0.63 10.0 0.2 2.0 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein Ion_trans PF00520.31 KFQ94612.1 - 7.5e-256 844.1 103.6 2.3e-79 266.1 17.3 4.1 4 0 0 4 4 4 4 Ion transport protein Na_trans_cytopl PF11933.8 KFQ94612.1 - 5.9e-83 277.9 10.3 1.5e-82 276.6 10.3 1.7 1 0 0 1 1 1 1 Cytoplasmic domain of voltage-gated Na+ ion channel Na_trans_assoc PF06512.13 KFQ94612.1 - 2.9e-66 223.7 1.5 2.9e-66 223.7 1.5 3.7 4 0 0 4 4 4 1 Sodium ion transport-associated PKD_channel PF08016.12 KFQ94612.1 - 3.2e-08 32.7 82.1 7.4e-05 21.6 0.6 9.6 6 4 4 10 10 10 7 Polycystin cation channel GPHH PF16905.5 KFQ94612.1 - 0.00011 21.9 0.0 0.00022 20.9 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated IQ PF00612.27 KFQ94612.1 - 0.0012 18.4 0.6 0.0032 17.1 0.6 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif ATP-synt_B PF00430.18 KFQ94612.1 - 0.0013 18.8 4.8 0.0013 18.8 4.8 3.5 5 0 0 5 5 5 1 ATP synthase B/B' CF(0) Neur_chan_memb PF02932.16 KFQ94612.1 - 0.018 15.1 0.2 0.018 15.1 0.2 4.9 7 0 0 7 7 7 0 Neurotransmitter-gated ion-channel transmembrane region SieB PF14163.6 KFQ94612.1 - 0.38 10.2 8.3 0.53 9.8 0.6 3.9 3 0 0 3 3 3 0 Super-infection exclusion protein B DUF4527 PF15030.6 KFQ94612.1 - 3.8 6.9 6.0 7.1 6.0 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) CSRNP_N PF16019.5 KFQ94613.1 - 3.4e-104 347.5 7.4 3.4e-104 347.5 7.4 2.2 2 0 0 2 2 2 1 Cysteine/serine-rich nuclear protein N-terminus Nop25 PF09805.9 KFQ94613.1 - 0.0098 16.4 6.4 0.74 10.3 0.1 2.6 2 0 0 2 2 2 2 Nucleolar protein 12 (25kDa) Spt5_N PF11942.8 KFQ94613.1 - 0.024 15.6 5.2 0.024 15.6 5.2 3.1 3 1 1 4 4 4 0 Spt5 transcription elongation factor, acidic N-terminal GOLD_2 PF13897.6 KFQ94613.1 - 0.14 12.6 1.9 0.44 11.0 1.9 2.0 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Nop14 PF04147.12 KFQ94613.1 - 1.5 6.9 17.7 0.028 12.6 7.3 2.1 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.10 KFQ94613.1 - 7 5.9 14.4 1.4 8.1 7.4 2.2 2 0 0 2 2 2 0 BUD22 Glycos_transf_2 PF00535.26 KFQ94614.1 - 1e-34 119.8 0.0 1.8e-34 119.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFQ94614.1 - 9.7e-25 87.3 0.6 1.6e-24 86.6 0.6 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 KFQ94614.1 - 5.4e-09 35.6 0.0 3.1e-08 33.2 0.1 2.0 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 KFQ94614.1 - 6e-06 26.3 0.0 1.3e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KFQ94614.1 - 0.00024 20.7 0.0 0.086 12.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Ion_trans PF00520.31 KFQ94615.1 - 7.8e-64 215.2 32.8 3.5e-55 186.9 21.4 2.6 3 0 0 3 3 3 2 Ion transport protein PKD_channel PF08016.12 KFQ94615.1 - 8e-07 28.1 23.6 2.8e-05 23.0 1.4 3.3 2 1 1 3 3 3 3 Polycystin cation channel GPHH PF16905.5 KFQ94615.1 - 2.2e-06 27.3 0.0 3.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated IQ PF00612.27 KFQ94615.1 - 0.0022 17.7 0.5 0.0048 16.6 0.5 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Ion_trans PF00520.31 KFQ94616.1 - 2.6e-160 531.2 64.4 2.3e-77 259.5 19.2 3.4 3 0 0 3 3 3 3 Ion transport protein Na_trans_cytopl PF11933.8 KFQ94616.1 - 1e-82 277.1 4.4 2.8e-82 275.7 4.4 1.7 1 0 0 1 1 1 1 Cytoplasmic domain of voltage-gated Na+ ion channel Na_trans_assoc PF06512.13 KFQ94616.1 - 3e-53 181.1 7.1 3e-53 181.1 7.1 2.4 2 1 0 2 2 2 1 Sodium ion transport-associated ATP-synt_B PF00430.18 KFQ94616.1 - 0.072 13.2 10.5 0.34 11.0 10.5 2.2 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Pox_A14 PF05767.12 KFQ94616.1 - 2.7 8.2 9.5 8.6 6.6 0.2 4.3 3 1 1 4 4 4 0 Poxvirus virion envelope protein A14 LIM PF00412.22 KFQ94617.1 - 2.1e-09 37.5 10.4 2.1e-09 37.5 10.4 2.2 2 0 0 2 2 2 1 LIM domain CTP-dep_RFKase PF01982.16 KFQ94617.1 - 0.41 10.7 2.2 1.3 9.1 1.4 2.3 1 1 1 2 2 2 0 Domain of unknown function DUF120 Galactosyl_T PF01762.21 KFQ94619.1 - 1.5e-60 204.4 0.0 1.9e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Pkinase PF00069.25 KFQ94620.1 - 9e-61 205.5 0.0 1.2e-60 205.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ94620.1 - 1.5e-44 152.2 0.0 2.3e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 KFQ94620.1 - 3.2e-22 78.5 0.1 8.3e-22 77.2 0.1 1.8 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Kinase-like PF14531.6 KFQ94620.1 - 0.00041 19.8 0.0 0.0007 19.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFQ94620.1 - 0.0007 18.5 0.0 0.002 17.0 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFQ94620.1 - 0.066 13.1 0.0 0.64 9.9 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 KFQ94620.1 - 0.077 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFQ94620.1 - 0.086 11.8 0.0 0.17 10.8 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain THEG4 PF15834.5 KFQ94620.1 - 0.16 11.9 0.1 0.55 10.2 0.0 1.8 2 0 0 2 2 2 0 Testis highly expressed protein 4 TRAM_LAG1_CLN8 PF03798.16 KFQ94622.1 - 8.2e-40 136.7 24.3 9.9e-40 136.4 24.3 1.1 1 0 0 1 1 1 1 TLC domain Homeodomain PF00046.29 KFQ94622.1 - 4.8e-07 29.5 1.0 8.4e-07 28.7 1.0 1.3 1 0 0 1 1 1 1 Homeodomain Spindle_Spc25 PF08234.12 KFQ94623.1 - 2.6e-23 82.0 0.3 2.6e-23 82.0 0.3 2.2 2 1 0 2 2 2 1 Chromosome segregation protein Spc25 Spc7 PF08317.11 KFQ94623.1 - 2.9e-05 23.1 15.2 3.8e-05 22.7 15.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4254 PF14063.6 KFQ94623.1 - 0.0023 17.7 2.8 0.0042 16.9 2.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4254) CENP-H PF05837.12 KFQ94623.1 - 0.0033 17.8 12.6 0.0033 17.8 12.6 1.7 2 0 0 2 2 2 1 Centromere protein H (CENP-H) DUF3584 PF12128.8 KFQ94623.1 - 0.0057 14.3 10.8 0.0064 14.1 10.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF3950 PF13132.6 KFQ94623.1 - 0.045 13.5 0.1 1.1 9.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3950) Exonuc_VII_L PF02601.15 KFQ94623.1 - 0.054 13.1 6.8 0.064 12.8 6.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 KFQ94623.1 - 0.067 12.3 14.8 0.094 11.8 14.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ubiquitin_2 PF14560.6 KFQ94623.1 - 0.068 13.6 2.8 0.62 10.6 0.0 2.5 2 1 0 2 2 2 0 Ubiquitin-like domain UPF0242 PF06785.11 KFQ94623.1 - 0.097 12.8 16.5 0.14 12.2 16.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DHR10 PF18595.1 KFQ94623.1 - 0.12 12.5 19.0 0.083 12.9 16.9 1.8 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Phage_GPO PF05929.11 KFQ94623.1 - 0.19 11.3 5.5 0.28 10.8 5.5 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase TMPIT PF07851.13 KFQ94623.1 - 0.24 10.6 11.1 0.33 10.2 11.1 1.3 1 0 0 1 1 1 0 TMPIT-like protein ATP-synt_F6 PF05511.11 KFQ94623.1 - 0.34 11.4 5.0 6.4 7.3 1.9 2.9 2 1 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 MCU PF04678.13 KFQ94623.1 - 0.36 10.9 4.0 0.61 10.2 4.0 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter CorA PF01544.18 KFQ94623.1 - 0.53 9.6 10.1 3 7.1 9.6 2.2 1 1 2 3 3 3 0 CorA-like Mg2+ transporter protein Bacillus_HBL PF05791.11 KFQ94623.1 - 0.61 9.9 12.0 0.47 10.3 2.5 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Tox-ODYAM1 PF15642.6 KFQ94623.1 - 0.63 9.0 11.4 1.1 8.2 11.4 1.4 1 1 0 1 1 1 0 Toxin in Odyssella and Amoebophilus FapA PF03961.13 KFQ94623.1 - 1 7.9 11.7 1.3 7.6 11.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF745 PF05335.13 KFQ94623.1 - 1.9 8.2 10.1 2.8 7.6 9.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Dynamin_N PF00350.23 KFQ94623.1 - 2 8.5 11.8 4.5 7.3 5.7 2.3 1 1 1 2 2 2 0 Dynamin family BST2 PF16716.5 KFQ94623.1 - 3 8.5 16.8 1.2 9.8 2.6 2.3 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Fib_alpha PF08702.10 KFQ94623.1 - 4.5 7.5 15.5 5.6 7.1 7.6 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family LMBR1 PF04791.16 KFQ94623.1 - 7.3 5.4 9.5 8.4 5.2 9.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF848 PF05852.11 KFQ94623.1 - 8.1 6.5 13.9 35 4.5 6.3 2.3 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF1664 PF07889.12 KFQ94623.1 - 9.5 6.3 11.1 17 5.5 7.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PAP2 PF01569.21 KFQ94624.1 - 2.8e-15 56.3 6.4 2.8e-15 56.3 6.4 1.8 2 0 0 2 2 2 1 PAP2 superfamily ABC_membrane PF00664.23 KFQ94625.1 - 3.4e-133 443.4 23.2 3.8e-74 249.8 3.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFQ94625.1 - 6e-74 247.0 0.4 1.7e-35 122.5 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFQ94625.1 - 2.6e-13 49.9 0.0 2e-06 27.4 0.3 3.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KFQ94625.1 - 2.5e-09 37.3 0.0 0.0016 18.4 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KFQ94625.1 - 8.9e-08 32.7 0.1 0.0088 16.4 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 KFQ94625.1 - 2e-06 27.2 0.2 0.0041 16.4 0.0 2.7 3 0 0 3 3 3 2 Zeta toxin AAA_15 PF13175.6 KFQ94625.1 - 8.4e-06 25.7 0.0 0.059 13.1 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KFQ94625.1 - 8.4e-06 26.1 0.1 0.06 13.6 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KFQ94625.1 - 3.5e-05 23.5 0.4 0.049 13.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 KFQ94625.1 - 0.00036 20.3 0.4 1.2 8.8 0.0 3.1 2 1 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 KFQ94625.1 - 0.00042 19.2 0.5 0.97 8.1 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_28 PF13521.6 KFQ94625.1 - 0.00045 20.5 0.1 10 6.4 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KFQ94625.1 - 0.00085 18.9 0.0 0.65 9.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region G-alpha PF00503.20 KFQ94625.1 - 0.001 18.3 0.0 1.2 8.2 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit Rad17 PF03215.15 KFQ94625.1 - 0.0024 17.8 0.0 0.16 11.9 0.0 2.8 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_33 PF13671.6 KFQ94625.1 - 0.01 16.0 0.1 7.5 6.7 0.0 2.8 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 KFQ94625.1 - 0.011 15.8 0.2 5.6 7.0 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_25 PF13481.6 KFQ94625.1 - 0.012 15.2 2.5 2.8 7.5 0.0 3.9 4 0 0 4 4 4 0 AAA domain AAA_21 PF13304.6 KFQ94625.1 - 0.012 15.4 0.0 0.26 11.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system SRP54 PF00448.22 KFQ94625.1 - 0.014 15.0 0.0 1.9 8.1 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KFQ94625.1 - 0.023 14.4 0.1 2 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 KFQ94625.1 - 0.034 13.8 0.0 3.4 7.3 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.6 KFQ94625.1 - 0.037 14.3 2.9 2.5 8.4 0.1 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit APS_kinase PF01583.20 KFQ94625.1 - 0.058 13.3 0.0 3.3 7.6 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.22 KFQ94625.1 - 0.075 13.4 0.0 8.4 6.8 0.0 2.9 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.23 KFQ94625.1 - 0.17 12.0 0.0 15 5.7 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase adh_short PF00106.25 KFQ94626.1 - 1.8e-38 132.0 0.0 2.4e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFQ94626.1 - 2.5e-25 89.4 0.0 4.1e-25 88.7 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HMG_box PF00505.19 KFQ94626.1 - 0.21 12.0 1.6 0.41 11.1 1.6 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box Ldl_recept_a PF00057.18 KFQ94627.1 - 0 1100.1 670.0 5.2e-12 45.8 10.0 38.1 38 1 0 38 38 38 36 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 KFQ94627.1 - 5.5e-207 670.1 95.6 2.2e-11 44.0 0.0 38.1 38 0 0 38 38 38 29 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 KFQ94627.1 - 2.1e-68 226.3 330.7 5.6e-10 39.3 5.5 24.2 22 1 0 22 22 22 16 Coagulation Factor Xa inhibitory site DUF5050 PF16472.5 KFQ94627.1 - 9.8e-36 123.4 0.4 1.5e-07 31.0 0.0 10.3 8 2 0 9 9 9 9 Domain of unknown function (DUF5050) cEGF PF12662.7 KFQ94627.1 - 1.3e-29 101.8 150.3 1e-09 38.1 2.6 19.3 19 0 0 19 19 19 10 Complement Clr-like EGF-like SGL PF08450.12 KFQ94627.1 - 6e-16 58.8 30.1 0.033 13.8 0.9 15.1 9 7 3 14 14 14 6 SMP-30/Gluconolactonase/LRE-like region EGF_CA PF07645.15 KFQ94627.1 - 3.5e-12 46.3 43.7 3.7e-08 33.4 6.9 34.0 30 9 11 42 42 42 6 Calcium-binding EGF domain Arylesterase PF01731.20 KFQ94627.1 - 0.00013 22.1 0.0 35 4.7 0.1 8.6 11 1 0 11 11 11 0 Arylesterase He_PIG PF05345.12 KFQ94627.1 - 0.13 12.5 1.0 45 4.4 0.3 4.2 3 0 0 3 3 3 0 Putative Ig domain VWA PF00092.28 KFQ94628.1 - 5e-70 235.3 1.5 1.2e-40 139.6 0.4 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain Collagen PF01391.18 KFQ94628.1 - 2.6e-68 225.7 286.7 2.3e-09 36.9 22.8 12.0 2 2 7 9 9 9 8 Collagen triple helix repeat (20 copies) VWA_2 PF13519.6 KFQ94628.1 - 3.1e-31 108.2 0.0 4.8e-20 72.2 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.6 KFQ94628.1 - 1.8e-05 24.7 0.0 0.0024 17.8 0.0 2.5 2 1 0 2 2 2 2 von Willebrand factor type A domain BBL5 PF07289.11 KFQ94629.1 - 7.2e-157 521.6 0.0 8.2e-157 521.4 0.0 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein Vps36_ESCRT-II PF11605.8 KFQ94629.1 - 0.00015 21.9 0.0 0.17 12.1 0.0 2.4 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 KFQ94629.1 - 0.00045 20.1 0.1 0.21 11.5 0.0 2.4 2 0 0 2 2 2 2 GRAM domain PH_TFIIH PF08567.11 KFQ94629.1 - 0.0026 18.1 0.0 0.46 10.8 0.0 2.5 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain bPH_3 PF14470.6 KFQ94629.1 - 0.0068 16.7 0.1 0.23 11.9 0.0 2.3 2 0 0 2 2 2 1 Bacterial PH domain POB3_N PF17292.2 KFQ94629.1 - 0.1 13.1 0.0 0.32 11.4 0.0 1.8 2 0 0 2 2 2 0 POB3-like N-terminal PH domain Voldacs PF03517.13 KFQ94629.1 - 0.16 12.1 1.1 24 5.0 0.1 2.8 2 1 1 3 3 3 0 Regulator of volume decrease after cellular swelling Kelch_1 PF01344.25 KFQ94630.1 - 4.4e-43 144.6 0.0 1.4e-09 37.4 0.0 5.5 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 KFQ94630.1 - 6.5e-31 106.5 0.7 1.7e-30 105.1 0.3 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFQ94630.1 - 1.8e-29 101.0 0.1 2.3e-08 34.0 0.0 5.6 2 1 3 5 5 5 5 Kelch motif BTB PF00651.31 KFQ94630.1 - 1.8e-28 99.0 0.5 3.9e-28 97.9 0.5 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 KFQ94630.1 - 9.9e-21 73.5 0.7 1.1e-06 28.6 0.0 5.5 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KFQ94630.1 - 1.1e-18 67.0 0.0 0.004 17.4 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KFQ94630.1 - 2.6e-17 62.0 0.2 0.11 12.5 0.0 5.5 4 1 1 5 5 5 5 Kelch motif Kelch_5 PF13854.6 KFQ94630.1 - 3.4e-12 46.1 0.0 0.43 10.6 0.0 5.4 5 0 0 5 5 5 4 Kelch motif DUF3342 PF11822.8 KFQ94630.1 - 0.0041 17.3 0.4 0.074 13.2 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) FAST_2 PF08368.12 KFQ94631.1 - 7.5e-31 106.8 2.9 1.3e-28 99.5 0.0 3.6 4 0 0 4 4 4 1 FAST kinase-like protein, subdomain 2 FAST_1 PF06743.15 KFQ94631.1 - 6.8e-20 70.8 20.1 3.1e-18 65.5 1.7 5.4 6 0 0 6 6 6 2 FAST kinase-like protein, subdomain 1 RAP PF08373.10 KFQ94631.1 - 5.6e-14 52.0 0.9 2e-13 50.2 0.0 2.5 3 0 0 3 3 3 1 RAP domain Pro_isomerase PF00160.21 KFQ94632.1 - 5.3e-48 163.3 0.2 5.3e-48 163.3 0.2 2.5 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SR-25 PF10500.9 KFQ94632.1 - 1.9e-07 31.0 40.0 1.9e-07 31.0 40.0 5.7 2 1 3 5 5 5 1 Nuclear RNA-splicing-associated protein Put_Phosphatase PF06888.12 KFQ94633.1 - 1.4e-92 309.4 0.1 1.5e-92 309.2 0.1 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 KFQ94633.1 - 3.7e-09 37.3 0.1 2.1e-08 34.8 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFQ94633.1 - 0.024 14.7 0.8 1.8 8.6 0.7 2.9 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Kelch_1 PF01344.25 KFQ94634.1 - 6.3e-48 160.1 33.0 6.7e-12 44.8 0.3 7.2 7 1 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 KFQ94634.1 - 6.8e-36 121.4 11.8 5.7e-09 35.9 0.1 6.4 3 2 3 6 6 6 6 Kelch motif BTB PF00651.31 KFQ94634.1 - 1.4e-30 105.8 0.9 2.2e-30 105.2 0.9 1.3 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 KFQ94634.1 - 7.6e-26 89.9 6.2 5.4e-05 23.1 0.0 6.4 5 1 1 6 6 6 5 Galactose oxidase, central domain BACK PF07707.15 KFQ94634.1 - 6.1e-25 87.3 1.9 6.1e-25 87.3 1.9 2.4 3 0 0 3 3 3 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 KFQ94634.1 - 4e-21 74.1 17.0 0.00076 19.4 0.0 7.1 6 2 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KFQ94634.1 - 3.2e-13 49.6 10.3 0.0013 18.9 0.1 5.5 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KFQ94634.1 - 1e-08 35.0 19.2 0.044 13.8 0.3 6.5 7 0 0 7 7 7 4 Kelch motif DUF3342 PF11822.8 KFQ94634.1 - 0.0025 18.0 0.1 0.0075 16.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Skp1_POZ PF03931.15 KFQ94634.1 - 0.066 13.4 0.0 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain RRM_3 PF08777.11 KFQ94635.1 - 6.3e-28 96.8 1.5 6.3e-28 96.8 1.5 3.0 3 1 0 3 3 3 1 RNA binding motif La PF05383.17 KFQ94635.1 - 6.2e-22 77.4 0.1 1.2e-21 76.5 0.1 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KFQ94635.1 - 1.4e-14 53.7 0.2 2.2e-09 37.0 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MTS PF05175.14 KFQ94636.1 - 5.7e-15 55.3 0.1 8.1e-15 54.8 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KFQ94636.1 - 1.8e-11 44.0 0.2 3.1e-11 43.2 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KFQ94636.1 - 9.2e-11 41.8 0.2 1.3e-10 41.3 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFQ94636.1 - 9.9e-10 39.0 0.4 2.2e-09 37.9 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KFQ94636.1 - 3.9e-09 36.4 0.0 5.2e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 KFQ94636.1 - 2.5e-07 30.6 0.5 2.4e-06 27.4 0.5 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.10 KFQ94636.1 - 3.6e-06 26.6 0.1 5.4e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_12 PF08242.12 KFQ94636.1 - 8e-05 23.3 0.1 0.00021 22.0 0.1 1.9 1 1 1 2 2 2 1 Methyltransferase domain DNA_methylase PF00145.17 KFQ94636.1 - 0.0031 16.9 0.2 0.0059 16.0 0.0 1.5 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase Methyltransf_4 PF02390.17 KFQ94636.1 - 0.0038 16.7 0.0 0.005 16.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase N6-adenineMlase PF10237.9 KFQ94636.1 - 0.0063 16.3 0.1 0.009 15.8 0.1 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase N6_Mtase PF02384.16 KFQ94636.1 - 0.0086 15.4 0.5 0.019 14.3 0.4 1.8 1 1 0 1 1 1 1 N-6 DNA Methylase FmrO PF07091.11 KFQ94636.1 - 0.01 15.4 0.1 0.025 14.1 0.1 1.7 1 1 1 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) Methyltr_RsmB-F PF01189.17 KFQ94636.1 - 0.014 15.0 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_16 PF10294.9 KFQ94636.1 - 0.017 14.9 1.0 0.027 14.2 0.1 1.8 2 1 0 2 2 2 0 Lysine methyltransferase DUF43 PF01861.16 KFQ94636.1 - 0.024 13.8 0.1 0.05 12.8 0.0 1.4 1 1 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_9 PF08003.11 KFQ94636.1 - 0.03 13.3 0.5 0.048 12.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 KFQ94636.1 - 0.066 13.2 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 KFQ94636.1 - 0.066 12.6 0.2 0.1 12.0 0.2 1.4 1 1 0 1 1 1 0 Tellurite resistance protein TehB zf-RING_5 PF14634.6 KFQ94637.1 - 0.0026 17.7 0.7 0.0026 17.7 0.7 3.3 3 0 0 3 3 3 1 zinc-RING finger domain CRAL_TRIO PF00650.20 KFQ94637.1 - 0.0078 15.9 0.4 0.03 14.0 0.4 2.1 1 0 0 1 1 1 1 CRAL/TRIO domain zf-C3HC4 PF00097.25 KFQ94637.1 - 0.016 15.1 0.5 0.016 15.1 0.5 3.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ94637.1 - 0.033 14.5 0.6 0.033 14.5 0.6 3.6 3 0 0 3 3 3 0 Ring finger domain Myosin_head PF00063.21 KFQ94638.1 - 8.8e-204 678.6 2.3 1.1e-203 678.3 2.3 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Pkinase PF00069.25 KFQ94638.1 - 2.8e-57 194.1 0.0 4.8e-57 193.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ94638.1 - 1.2e-40 139.4 0.0 2.1e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFQ94638.1 - 4e-06 25.9 0.0 7.2e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFQ94638.1 - 5.1e-06 26.6 0.0 0.078 12.9 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family IQ PF00612.27 KFQ94638.1 - 0.00017 21.1 5.8 0.011 15.5 0.0 3.0 3 0 0 3 3 3 2 IQ calmodulin-binding motif Kinase-like PF14531.6 KFQ94638.1 - 0.00023 20.6 0.0 0.00047 19.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like AAA_22 PF13401.6 KFQ94638.1 - 0.023 15.0 0.0 0.071 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFQ94638.1 - 0.08 13.3 0.0 0.38 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 KFQ94638.1 - 0.14 11.4 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin APH_6_hur PF04655.14 KFQ94638.1 - 0.15 11.4 0.1 0.5 9.7 0.0 1.9 2 0 0 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase AAA_18 PF13238.6 KFQ94638.1 - 0.16 12.5 0.0 7.9 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain zf-C2H2 PF00096.26 KFQ94639.1 - 2.6e-19 68.5 14.2 3.9e-07 30.2 0.9 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ94639.1 - 2.8e-17 62.3 7.8 7.2e-10 38.8 1.1 3.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ94639.1 - 2.3e-13 49.7 14.6 1.2e-05 25.7 1.4 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFQ94639.1 - 6.9e-06 25.9 12.3 0.0028 17.6 0.8 3.7 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ94639.1 - 2.5e-05 24.5 2.0 0.46 10.8 0.2 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFQ94639.1 - 0.00021 21.5 4.2 0.00034 20.8 2.3 2.2 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 KFQ94639.1 - 0.00037 20.4 8.0 1.6 8.8 0.2 3.2 1 1 2 3 3 3 3 BED zinc finger zf-met PF12874.7 KFQ94639.1 - 0.0013 19.1 4.5 2.1 8.8 0.4 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFQ94639.1 - 0.0014 18.9 2.6 0.0016 18.7 2.6 1.1 1 0 0 1 1 1 1 C2H2-type zinc ribbon FOXP-CC PF16159.5 KFQ94639.1 - 0.0019 18.8 5.1 0.32 11.7 0.3 3.0 1 1 2 3 3 3 1 FOXP coiled-coil domain zf-LYAR PF08790.11 KFQ94639.1 - 0.003 17.4 1.7 1.5 8.8 0.1 3.0 3 0 0 3 3 3 1 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 KFQ94639.1 - 0.0036 16.9 1.7 0.089 12.4 0.1 2.9 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger zf_C2H2_ZHX PF18387.1 KFQ94639.1 - 0.0098 15.5 5.1 0.36 10.5 0.2 2.8 1 1 2 3 3 3 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_3rep PF18868.1 KFQ94639.1 - 0.015 16.0 3.8 2 9.1 0.4 2.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 KFQ94639.1 - 0.025 14.4 0.3 0.025 14.4 0.3 3.8 3 1 0 3 3 3 0 C2H2-type zinc-finger domain Zn-ribbon_8 PF09723.10 KFQ94639.1 - 0.027 14.6 1.5 0.086 13.0 1.5 1.9 1 1 0 1 1 1 0 Zinc ribbon domain Ogr_Delta PF04606.12 KFQ94639.1 - 0.032 14.2 0.2 8.7 6.4 0.1 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Zn-C2H2_12 PF18112.1 KFQ94639.1 - 0.032 14.7 7.0 3.9 8.0 2.9 3.4 3 2 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2HE PF16278.5 KFQ94639.1 - 0.033 14.6 10.4 4 8.0 0.4 3.2 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger XPA_N PF01286.18 KFQ94639.1 - 0.041 13.9 0.5 0.49 10.5 0.1 2.3 2 0 0 2 2 2 0 XPA protein N-terminal zinc_ribbon_9 PF14369.6 KFQ94639.1 - 0.047 14.0 1.4 0.087 13.1 0.1 1.9 2 0 0 2 2 2 0 zinc-ribbon zf-C2H2_2 PF12756.7 KFQ94639.1 - 0.054 13.8 3.6 5.7 7.3 0.7 2.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF1610 PF07754.11 KFQ94639.1 - 0.13 12.2 0.6 0.13 12.2 0.6 2.3 4 0 0 4 4 3 0 Domain of unknown function (DUF1610) Zn_Tnp_IS1595 PF12760.7 KFQ94639.1 - 0.14 12.2 0.6 0.14 12.2 0.6 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.6 KFQ94639.1 - 0.14 11.6 1.3 0.88 9.1 0.0 2.5 3 0 0 3 3 3 0 zinc-ribbon domain ADK_lid PF05191.14 KFQ94639.1 - 0.15 12.1 1.5 1.4 9.0 0.2 2.5 2 1 0 2 2 2 0 Adenylate kinase, active site lid zf-C2H2_9 PF16293.5 KFQ94639.1 - 0.29 11.0 2.9 0.51 10.2 0.1 2.2 3 0 0 3 3 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 KFQ94639.1 - 2.3 8.0 8.4 1.6 8.6 0.5 2.8 3 0 0 3 3 3 0 zinc-finger C2H2-type Pyridoxal_deC PF00282.19 KFQ94640.1 - 4.8e-152 506.0 0.0 5.6e-152 505.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KFQ94640.1 - 1.7e-05 24.3 0.0 3.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KFQ94640.1 - 1.7e-05 24.0 0.0 0.00019 20.6 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KFQ94640.1 - 0.0056 16.0 0.0 0.0075 15.6 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SepSecS PF05889.13 KFQ94640.1 - 0.0093 14.7 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS OKR_DC_1 PF01276.20 KFQ94640.1 - 0.029 13.1 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_1_2 PF00155.21 KFQ94640.1 - 0.078 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II GRASP55_65 PF04495.14 KFQ94641.1 - 6e-70 233.9 0.0 2.4e-54 183.4 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KFQ94641.1 - 2.5e-08 33.6 0.0 0.0031 17.3 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFQ94641.1 - 9.2e-07 29.1 0.0 0.044 14.1 0.0 2.8 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 KFQ94641.1 - 0.13 12.6 0.0 32 5.0 0.0 2.5 2 0 0 2 2 2 0 PDZ domain Pkinase PF00069.25 KFQ94642.1 - 1.5e-61 208.1 0.0 1.5e-61 208.1 0.0 1.9 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ94642.1 - 2.3e-34 118.8 0.0 5.4e-34 117.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Vir_act_alpha_C PF10400.9 KFQ94642.1 - 3.5 8.4 16.9 2.4 8.9 3.5 3.7 3 1 0 3 3 3 0 Virulence activator alpha C-term Methyltransf_23 PF13489.6 KFQ94643.1 - 1e-13 51.5 0.0 2.3e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFQ94643.1 - 2.4e-13 50.6 0.1 9.7e-13 48.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFQ94643.1 - 1.1e-11 45.3 0.1 3.5e-11 43.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFQ94643.1 - 2.6e-11 44.0 0.0 5.6e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFQ94643.1 - 2.3e-06 27.5 0.0 5.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 KFQ94643.1 - 0.0088 15.5 0.0 0.2 11.2 0.0 2.3 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_24 PF13578.6 KFQ94643.1 - 0.011 16.8 0.0 0.032 15.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain NodS PF05401.11 KFQ94643.1 - 0.026 14.1 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) MTS PF05175.14 KFQ94643.1 - 0.084 12.4 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Gal-bind_lectin PF00337.22 KFQ94643.1 - 0.67 9.5 3.5 0.75 9.3 2.2 1.7 1 1 0 1 1 1 0 Galactoside-binding lectin DCAF17 PF15802.5 KFQ94644.1 - 1.6e-223 742.7 0.1 1.8e-223 742.5 0.1 1.0 1 0 0 1 1 1 1 DDB1- and CUL4-associated factor 17 Cytochrom_B561 PF03188.16 KFQ94645.1 - 1.4e-36 125.6 9.3 1.4e-36 125.6 9.3 1.5 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 KFQ94645.1 - 5 7.3 12.2 2.7 8.1 8.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) Dynein_IC2 PF11540.8 KFQ94646.1 - 3.4e-15 55.7 0.6 7.2e-15 54.6 0.6 1.6 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 WD40 PF00400.32 KFQ94646.1 - 1.9e-07 31.7 10.3 0.096 13.6 0.3 7.1 7 0 0 7 7 7 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ94646.1 - 0.0012 19.1 0.0 0.028 14.7 0.0 3.1 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain MAT1 PF06391.13 KFQ94646.1 - 0.15 11.9 15.8 1.7 8.4 7.5 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Mito_carr PF00153.27 KFQ94647.1 - 2.8e-73 241.9 0.6 9.7e-26 89.5 0.1 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KFQ94647.1 - 1.5e-12 46.1 1.9 0.014 14.9 0.1 5.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFQ94647.1 - 4.9e-12 44.8 2.8 0.013 15.4 0.0 6.0 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 KFQ94647.1 - 8.6e-11 42.1 1.9 0.0018 18.7 0.0 4.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 KFQ94647.1 - 1.4e-05 24.8 0.2 0.012 15.4 0.0 3.9 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 KFQ94647.1 - 8.5e-05 21.9 0.5 2.3 7.8 0.0 4.1 3 0 0 3 3 3 2 EF hand DUF4734 PF15881.5 KFQ94647.1 - 0.18 12.0 1.3 0.39 10.9 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4734) Hat1_N PF10394.9 KFQ94648.1 - 2.1e-41 141.8 0.7 4.3e-41 140.8 0.5 1.6 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 KFQ94648.1 - 0.025 14.8 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFQ94648.1 - 0.037 14.0 0.0 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFQ94648.1 - 0.047 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_M24 PF00557.24 KFQ94649.1 - 2.7e-55 187.3 0.0 3.3e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Homeodomain PF00046.29 KFQ94650.1 - 4.4e-12 45.6 1.0 7.2e-12 45.0 1.0 1.3 1 0 0 1 1 1 1 Homeodomain HTH_AsnC-type PF13404.6 KFQ94650.1 - 0.17 11.7 0.7 0.29 11.0 0.7 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Integrin_alpha2 PF08441.12 KFQ94651.1 - 2.1e-127 425.9 3.5 2.7e-127 425.5 3.5 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 KFQ94651.1 - 5.3e-19 68.0 26.3 2.2e-09 37.3 6.7 4.3 4 0 0 4 4 4 3 FG-GAP repeat VCBS PF13517.6 KFQ94651.1 - 1.9e-14 54.0 12.4 1.7e-10 41.3 2.6 3.1 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BCDHK_Adom3 PF10436.9 KFQ94653.1 - 1.6e-48 164.6 0.0 2.7e-48 163.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KFQ94653.1 - 1.1e-14 54.8 0.0 2.1e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFQ94653.1 - 0.00053 19.8 0.0 0.00093 19.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PDZ_5 PF17817.1 KFQ94654.1 - 2.5e-27 94.9 4.1 2.5e-27 94.9 4.1 3.0 3 0 0 3 3 3 1 PDZ domain PDZ PF00595.24 KFQ94654.1 - 2.3e-13 50.3 3.4 3.2e-13 49.8 1.9 2.1 2 0 0 2 2 2 1 PDZ domain SAM_2 PF07647.17 KFQ94654.1 - 7.3e-09 35.6 0.4 1.8e-08 34.4 0.4 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFQ94654.1 - 1.1e-07 32.2 0.9 1.1e-07 32.2 0.9 2.4 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) PDZ_6 PF17820.1 KFQ94654.1 - 4.7e-05 23.1 0.6 0.00031 20.5 0.1 2.7 3 0 0 3 3 3 1 PDZ domain SAM_PNT PF02198.16 KFQ94654.1 - 0.00052 19.9 1.4 0.0012 18.7 1.4 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PDZ_2 PF13180.6 KFQ94654.1 - 0.015 15.6 0.3 0.051 13.9 0.3 1.9 1 0 0 1 1 1 0 PDZ domain SAM_3 PF18016.1 KFQ94654.1 - 0.13 12.1 0.9 0.57 10.0 0.2 2.4 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Atg14 PF10186.9 KFQ94654.1 - 1.8 7.6 16.1 4.9 6.1 16.1 1.7 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RasGEF PF00617.19 KFQ94655.1 - 3.4e-52 177.2 1.7 7e-52 176.2 1.7 1.6 1 0 0 1 1 1 1 RasGEF domain cNMP_binding PF00027.29 KFQ94655.1 - 1.7e-35 121.0 0.0 4.8e-16 58.6 0.0 3.6 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain DEP PF00610.21 KFQ94655.1 - 3.3e-22 78.3 2.7 1.1e-21 76.7 1.3 2.3 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RasGEF_N PF00618.20 KFQ94655.1 - 6.9e-12 45.5 0.0 1.9e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif RA PF00788.23 KFQ94655.1 - 0.038 14.6 0.0 0.15 12.7 0.0 2.0 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Pkinase_Tyr PF07714.17 KFQ94656.1 - 2.3e-63 213.9 0.0 4.4e-63 213.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ94656.1 - 5.7e-56 189.8 0.0 1e-55 188.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SAM_1 PF00536.30 KFQ94656.1 - 5.3e-10 39.6 4.1 5e-09 36.5 0.3 3.3 4 0 0 4 4 4 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFQ94656.1 - 3.2e-09 36.7 0.2 8.6e-09 35.4 0.1 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFQ94656.1 - 0.0061 16.5 0.1 0.019 14.9 0.1 1.8 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_4 PF18017.1 KFQ94656.1 - 0.034 14.1 0.0 0.22 11.5 0.0 2.3 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) DUF3552 PF12072.8 KFQ94656.1 - 2 7.8 4.9 3.5 7.0 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) APG6_N PF17675.1 KFQ94656.1 - 2.3 8.7 7.9 0.2 12.2 3.0 1.6 2 0 0 2 2 2 0 Apg6 coiled-coil region zf-H2C2_2 PF13465.6 KFQ94657.1 - 2.2e-13 50.0 22.8 1.2e-07 31.9 2.4 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ94657.1 - 2.7e-13 49.6 28.1 2e-05 24.8 2.2 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ94657.1 - 8e-06 26.3 30.3 0.00081 20.0 1.8 3.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-Di19 PF05605.12 KFQ94657.1 - 0.0089 16.3 2.2 0.0089 16.3 2.2 2.8 1 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KFQ94657.1 - 0.013 15.4 15.3 0.15 12.1 1.4 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFQ94657.1 - 0.12 12.7 6.5 0.13 12.6 4.8 2.0 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KFQ94657.1 - 0.14 12.5 4.8 1.7 9.1 1.2 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 KFQ94657.1 - 0.27 10.9 2.3 4.2 7.1 0.7 2.6 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain YchF-GTPase_C PF06071.13 KFQ94658.1 - 6.2e-42 141.7 0.4 2.2e-41 139.9 0.4 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KFQ94658.1 - 1.9e-23 82.7 0.0 5.7e-23 81.2 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFQ94658.1 - 2e-07 30.6 0.0 4.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 KFQ94658.1 - 0.0037 17.3 0.0 0.0082 16.2 0.0 1.5 1 0 0 1 1 1 1 TGS domain MeaB PF03308.16 KFQ94658.1 - 0.0061 15.6 0.2 0.015 14.3 0.0 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 KFQ94658.1 - 0.013 15.8 0.0 1.4 9.2 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KFQ94658.1 - 0.074 13.1 0.0 9.2 6.3 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 KFQ94658.1 - 0.086 13.4 0.0 0.77 10.3 0.0 2.5 2 1 1 3 3 3 0 AAA domain Yae1_N PF09811.9 KFQ94659.1 - 4.3e-13 48.7 41.5 1.8e+04 -6.2 41.5 4.1 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Peptidase_C69 PF03577.15 KFQ94661.1 - 2.3e-09 36.7 0.1 3.2e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase family C69 AAT PF03417.16 KFQ94661.1 - 0.0073 16.0 0.1 0.08 12.6 0.0 2.4 2 1 0 2 2 2 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Ca_bind_SSO6904 PF18249.1 KFQ94661.1 - 0.094 13.1 0.2 13 6.2 0.0 2.8 3 0 0 3 3 3 0 Calcium binding protein SSO6904 Mem_trans PF03547.18 KFQ94662.1 - 9.1e-19 67.1 21.4 9.2e-14 50.6 6.8 3.1 2 1 1 3 3 3 2 Membrane transport protein DEP PF00610.21 KFQ94662.1 - 1.2e-12 47.7 0.0 2.7e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) MMgT PF10270.9 KFQ94662.1 - 0.17 12.2 2.1 4.7 7.6 1.4 3.0 1 1 0 1 1 1 0 Membrane magnesium transporter Neur_chan_LBD PF02931.23 KFQ94663.1 - 2.1e-71 239.8 1.5 2.7e-71 239.4 1.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFQ94663.1 - 6.6e-69 232.6 12.2 3.2e-53 181.2 9.6 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF2207 PF09972.9 KFQ94663.1 - 1.3 7.7 4.7 15 4.2 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF1129 PF06570.11 KFQ94663.1 - 9.8 5.6 9.1 22 4.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) RhoGAP PF00620.27 KFQ94664.1 - 2.7e-50 170.1 0.0 4.7e-50 169.4 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 KFQ94664.1 - 3.8e-16 58.7 7.5 6.8e-16 57.9 7.5 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH2 PF00017.24 KFQ94664.1 - 5.6e-14 52.0 0.1 1.4e-13 50.8 0.1 1.6 1 0 0 1 1 1 1 SH2 domain FYVE_2 PF02318.16 KFQ94664.1 - 0.042 14.1 2.1 0.08 13.2 2.1 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger PHD_2 PF13831.6 KFQ94664.1 - 0.065 12.8 1.6 0.15 11.7 1.6 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 KFQ94664.1 - 0.27 11.6 5.1 0.57 10.5 5.1 1.5 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 KFQ94664.1 - 2.9 7.8 7.6 5.9 6.9 7.6 1.5 1 0 0 1 1 1 0 PHD-finger bZIP_1 PF00170.21 KFQ94665.1 - 3.2e-12 46.4 7.0 5e-12 45.7 7.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFQ94665.1 - 4.1e-09 36.4 7.7 9.3e-09 35.2 7.7 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFQ94665.1 - 0.0044 17.5 7.7 0.011 16.2 7.7 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor zf-C2H2 PF00096.26 KFQ94665.1 - 0.028 14.9 1.5 0.054 14.0 1.5 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type KxDL PF10241.9 KFQ94665.1 - 0.78 10.1 3.0 2.1 8.7 1.8 2.2 3 0 0 3 3 3 0 Uncharacterized conserved protein ATP-synt_C PF00137.21 KFQ94666.1 - 1.2e-11 44.7 12.4 1.8e-11 44.2 12.4 1.2 1 0 0 1 1 1 1 ATP synthase subunit C zinc_ribbon_10 PF10058.9 KFQ94667.1 - 1.6e-21 75.7 0.3 2.5e-21 75.1 0.3 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein DUF4153 PF13687.6 KFQ94667.1 - 0.00095 18.9 0.2 0.0015 18.2 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4153) DUF2207 PF09972.9 KFQ94667.1 - 0.0087 14.9 0.3 0.012 14.5 0.3 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Homeodomain PF00046.29 KFQ94669.1 - 3.5e-19 68.4 6.1 4.2e-19 68.2 6.1 1.1 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ94669.1 - 0.00024 20.9 3.4 0.00026 20.8 2.3 1.6 1 1 0 1 1 1 1 Homeobox KN domain DUF1510 PF07423.11 KFQ94669.1 - 0.031 14.4 0.1 0.034 14.3 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1510) HTH_23 PF13384.6 KFQ94669.1 - 0.049 13.5 0.1 0.071 12.9 0.1 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HLH PF00010.26 KFQ94670.1 - 5e-11 42.4 0.2 6.8e-11 42.0 0.2 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_51 PF18558.1 KFQ94670.1 - 0.0011 18.8 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Hist_deacetyl PF00850.19 KFQ94671.1 - 3.6e-81 273.0 0.0 3.6e-81 273.0 0.0 2.5 3 1 0 3 3 3 1 Histone deacetylase domain HDAC4_Gln PF12203.8 KFQ94671.1 - 5.9e-35 119.3 47.7 5.9e-35 119.3 47.7 4.0 4 0 0 4 4 4 1 Glutamine rich N terminal domain of histone deacetylase 4 U-box PF04564.15 KFQ94671.1 - 0.68 10.2 4.3 7.7 6.8 0.2 3.5 3 0 0 3 3 3 0 U-box domain JAB PF01398.21 KFQ94672.1 - 9.5e-33 112.7 0.1 2.6e-32 111.2 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KFQ94672.1 - 4.4e-16 59.3 1.3 7.8e-16 58.5 1.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KFQ94672.1 - 2.1e-06 27.5 0.0 3.5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain RRM_1 PF00076.22 KFQ94673.1 - 4.8e-33 112.8 0.0 3.2e-16 58.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KFQ94673.1 - 0.00068 19.8 0.0 0.95 9.7 0.0 2.3 2 0 0 2 2 2 2 BRCA1-associated protein 2 RRM_7 PF16367.5 KFQ94673.1 - 0.12 12.5 0.0 15 5.8 0.0 2.5 2 1 0 2 2 2 0 RNA recognition motif Integrin_beta PF00362.18 KFQ94674.1 - 2.9e-110 367.8 0.0 4.7e-110 367.1 0.0 1.3 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_b_cyt PF08725.11 KFQ94674.1 - 5.1e-19 67.7 0.4 8.3e-19 67.0 0.4 1.4 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain PSI_integrin PF17205.3 KFQ94674.1 - 2.1e-14 53.0 7.2 2.1e-14 53.0 7.2 4.9 5 0 0 5 5 5 1 Integrin plexin domain Integrin_B_tail PF07965.12 KFQ94674.1 - 1.2e-13 51.3 5.7 1.2e-13 51.3 5.7 4.5 3 1 1 5 5 5 1 Integrin beta tail domain I-EGF_1 PF18372.1 KFQ94674.1 - 6.9e-12 45.2 8.8 6.9e-12 45.2 8.8 6.8 8 0 0 8 8 8 4 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 KFQ94674.1 - 1.7e-05 25.1 63.9 0.00053 20.3 19.7 8.3 8 2 2 10 10 10 4 EGF-like domain Lectin_C PF00059.21 KFQ94675.1 - 1.5e-118 389.2 46.6 3.7e-17 63.0 0.4 8.6 8 0 0 8 8 8 8 Lectin C-type domain fn2 PF00040.19 KFQ94675.1 - 2.2e-15 56.6 13.5 2.2e-15 56.6 13.5 2.6 2 0 0 2 2 2 1 Fibronectin type II domain UL45 PF05473.12 KFQ94675.1 - 7.9e-14 51.8 6.5 0.0003 20.5 0.1 7.1 5 2 1 6 6 6 4 UL45 protein, carbohydrate-binding C-type lectin-like Xlink PF00193.17 KFQ94675.1 - 0.0016 18.8 15.2 0.69 10.3 0.0 7.7 8 1 0 8 8 8 1 Extracellular link domain Chordopox_A33R PF05966.12 KFQ94675.1 - 0.013 14.8 6.2 1.3 8.2 0.1 4.7 5 0 0 5 5 5 0 Chordopoxvirus A33R protein Lectin_C PF00059.21 KFQ94676.1 - 5.1e-135 442.2 72.1 2.2e-18 67.0 0.2 11.7 12 1 0 12 12 12 10 Lectin C-type domain fn2 PF00040.19 KFQ94676.1 - 2.3e-14 53.4 7.3 2.3e-14 53.4 7.3 2.6 2 0 0 2 2 2 1 Fibronectin type II domain UL45 PF05473.12 KFQ94676.1 - 1.3e-07 31.4 27.6 0.023 14.3 0.2 9.1 9 2 2 11 11 11 5 UL45 protein, carbohydrate-binding C-type lectin-like Ricin_B_lectin PF00652.22 KFQ94676.1 - 0.01 16.1 1.3 0.01 16.1 1.3 3.6 4 0 0 4 4 4 1 Ricin-type beta-trefoil lectin domain Xlink PF00193.17 KFQ94676.1 - 0.24 11.8 19.4 27 5.2 0.0 9.1 11 1 0 11 11 11 0 Extracellular link domain HCO3_cotransp PF00955.21 KFQ94677.1 - 8.7e-204 678.0 23.8 1.7e-123 413.2 9.7 2.2 1 1 1 2 2 2 2 HCO3- transporter family Band_3_cyto PF07565.13 KFQ94677.1 - 2.5e-106 355.4 0.5 2.5e-106 355.4 0.5 3.1 4 0 0 4 4 4 1 Band 3 cytoplasmic domain BUD22 PF09073.10 KFQ94677.1 - 3.8e-06 26.5 3.0 3.8e-06 26.5 3.0 2.5 2 1 0 2 2 2 1 BUD22 PTS_EIIA_2 PF00359.22 KFQ94677.1 - 0.00017 21.5 0.0 0.00035 20.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 NPR3 PF03666.13 KFQ94677.1 - 0.064 12.0 10.0 0.13 11.1 7.2 2.3 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM176 PF14851.6 KFQ94677.1 - 9.5 5.9 12.7 15 5.2 7.5 2.9 2 0 0 2 2 2 0 FAM176 family LIP1 PF15904.5 KFQ94678.1 - 3.8e-36 123.3 2.0 9e-36 122.1 2.0 1.7 1 0 0 1 1 1 1 LKB1 serine/threonine kinase interacting protein 1 LRR_8 PF13855.6 KFQ94678.1 - 1e-10 41.2 19.7 2.5e-05 23.9 5.5 4.1 2 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KFQ94678.1 - 1.1e-10 41.6 21.2 2.1e-06 28.0 1.3 5.2 3 3 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFQ94678.1 - 1.2e-06 28.1 1.1 4e-06 26.4 1.1 1.9 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 KFQ94678.1 - 0.21 12.3 18.5 37 5.4 0.1 7.6 7 0 0 7 7 7 0 Leucine Rich Repeat Connexin PF00029.19 KFQ94679.1 - 7.7e-96 320.4 0.0 8.6e-96 320.2 0.0 1.0 1 0 0 1 1 1 1 Connexin TGF_beta PF00019.20 KFQ94680.1 - 2.3e-15 57.5 0.9 2.4e-14 54.1 0.9 2.3 1 1 0 1 1 1 1 Transforming growth factor beta like domain DUF4203 PF13886.6 KFQ94681.1 - 8.7e-50 169.2 37.3 1e-49 168.9 37.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) ASC PF00858.24 KFQ94682.1 - 2.9e-106 356.1 0.0 3.9e-106 355.7 0.0 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.24 KFQ94683.1 - 6.3e-18 65.0 0.0 7.1e-18 64.8 0.0 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Rnk_N PF14760.6 KFQ94683.1 - 0.054 14.0 0.1 11 6.6 0.0 2.4 2 0 0 2 2 2 0 Rnk N-terminus Uso1_p115_C PF04871.13 KFQ94684.1 - 0.082 13.3 6.0 0.13 12.7 6.0 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Golgin_A5 PF09787.9 KFQ94684.1 - 0.11 11.9 6.5 0.14 11.6 6.5 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 5_nucleotid PF05761.14 KFQ94684.1 - 0.12 11.2 0.9 0.15 11.0 0.9 1.0 1 0 0 1 1 1 0 5' nucleotidase family Rootletin PF15035.6 KFQ94684.1 - 0.15 12.1 9.9 0.2 11.6 9.9 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Ufd2P_core PF10408.9 KFQ94684.1 - 0.23 10.0 2.2 0.28 9.8 2.2 1.0 1 0 0 1 1 1 0 Ubiquitin elongating factor core YabA PF06156.13 KFQ94684.1 - 0.36 11.5 4.1 0.53 11.0 4.1 1.2 1 0 0 1 1 1 0 Initiation control protein YabA ERM PF00769.19 KFQ94684.1 - 0.7 9.7 13.3 0.92 9.3 13.3 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family CENP-K PF11802.8 KFQ94684.1 - 0.72 9.4 6.9 0.97 8.9 6.9 1.1 1 0 0 1 1 1 0 Centromere-associated protein K APG6_N PF17675.1 KFQ94684.1 - 0.91 10.1 12.6 2.5 8.6 12.6 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region YlqD PF11068.8 KFQ94684.1 - 1.2 9.6 7.8 1.7 9.1 7.8 1.2 1 0 0 1 1 1 0 YlqD protein UPF0242 PF06785.11 KFQ94684.1 - 3.5 7.7 7.8 4.8 7.2 7.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus RhoGAP PF00620.27 KFQ94685.1 - 2.8e-36 124.6 0.0 3.5e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 KFQ94685.1 - 3.9e-07 29.9 4.6 7.3e-07 29.0 4.6 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KFQ94685.1 - 0.016 15.5 0.7 0.038 14.3 0.7 1.6 1 0 0 1 1 1 0 C1 domain PHD PF00628.29 KFQ94685.1 - 0.22 11.5 7.6 0.44 10.5 7.6 1.5 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 KFQ94685.1 - 0.6 10.1 8.0 1.7 8.6 8.0 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 DZR PF12773.7 KFQ94685.1 - 2.8 8.0 9.7 11 6.1 8.8 2.2 2 0 0 2 2 2 0 Double zinc ribbon NTP_transferase PF00483.23 KFQ94686.1 - 7.8e-17 61.7 0.0 1.2e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KFQ94686.1 - 3e-09 36.2 11.0 5.7e-07 29.0 2.0 3.7 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 KFQ94686.1 - 0.0025 16.0 0.1 0.0037 15.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 KFQ94686.1 - 0.015 15.1 0.4 0.11 12.3 0.5 2.5 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Pkinase PF00069.25 KFQ94687.1 - 2.2e-22 79.7 0.5 2.3e-22 79.6 0.5 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ94687.1 - 9.4e-14 51.3 0.2 1.1e-13 51.1 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase I-set PF07679.16 KFQ94688.1 - 1e-19 70.4 0.0 1.2e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ94688.1 - 6.7e-13 49.0 0.0 8.9e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFQ94688.1 - 1.6e-08 34.6 0.0 1.8e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFQ94688.1 - 6.7e-08 32.7 0.0 8.8e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KFQ94688.1 - 1.1e-06 28.8 0.0 1.4e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 KFQ94688.1 - 0.0005 19.6 0.0 0.00074 19.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFQ94688.1 - 0.00086 19.3 0.0 0.001 19.0 0.0 1.2 1 0 0 1 1 1 1 C17orf99 Ig domain Filament PF00038.21 KFQ94689.1 - 3.8e-115 384.8 47.7 4.5e-115 384.5 47.7 1.1 1 0 0 1 1 1 1 Intermediate filament protein Filament_head PF04732.14 KFQ94689.1 - 1.4e-26 93.1 13.1 3.2e-26 92.0 13.1 1.6 1 0 0 1 1 1 1 Intermediate filament head (DNA binding) region Golgin_A5 PF09787.9 KFQ94689.1 - 0.0063 16.0 37.1 0.12 11.8 21.3 2.4 1 1 1 2 2 2 2 Golgin subfamily A member 5 TolA_bind_tri PF16331.5 KFQ94689.1 - 0.0088 16.1 1.4 0.0088 16.1 1.4 6.2 4 2 0 5 5 5 1 TolA binding protein trimerisation Trimer_CC PF08954.11 KFQ94689.1 - 0.018 14.6 0.2 0.018 14.6 0.2 4.3 3 1 1 4 4 4 0 Trimerisation motif Jnk-SapK_ap_N PF09744.9 KFQ94689.1 - 0.039 14.2 41.1 0.2 11.9 15.9 3.9 1 1 3 4 4 4 0 JNK_SAPK-associated protein-1 GAS PF13851.6 KFQ94689.1 - 0.16 11.3 43.4 0.23 10.8 11.5 4.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.8 KFQ94689.1 - 0.19 9.2 38.2 2.5 5.5 38.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) FAM184 PF15665.5 KFQ94689.1 - 0.19 11.5 42.7 0.76 9.5 8.5 3.3 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B Patched PF02460.18 KFQ94689.1 - 0.22 9.6 4.5 0.29 9.1 4.5 1.1 1 0 0 1 1 1 0 Patched family DUF1664 PF07889.12 KFQ94689.1 - 0.29 11.2 20.7 0.64 10.1 1.2 4.1 1 1 3 5 5 5 0 Protein of unknown function (DUF1664) KLRAQ PF10205.9 KFQ94689.1 - 0.32 11.3 26.1 0.15 12.3 11.0 4.0 2 2 1 3 3 3 0 Predicted coiled-coil domain-containing protein Spc7 PF08317.11 KFQ94689.1 - 0.34 9.7 42.3 0.052 12.4 7.1 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 KFQ94689.1 - 0.42 10.7 16.6 4.1 7.4 0.4 4.3 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 KFQ94689.1 - 2.1 8.7 10.0 29 5.0 0.0 4.2 2 2 3 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF4515 PF14988.6 KFQ94689.1 - 2.5 7.9 41.3 0.035 13.9 7.6 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4515) KASH_CCD PF14662.6 KFQ94689.1 - 2.9 7.7 40.6 10 5.9 15.7 3.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 KFQ94689.1 - 3.4 7.7 44.0 5.5 7.1 9.2 4.3 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein WD40_alt PF14077.6 KFQ94689.1 - 3.8 7.4 10.7 31 4.5 1.3 4.4 4 0 0 4 4 3 0 Alternative WD40 repeat motif T6PP_N PF18572.1 KFQ94689.1 - 5.3 6.9 14.8 0.32 10.9 7.2 2.9 2 2 1 3 3 3 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain CENP-H PF05837.12 KFQ94689.1 - 5.7 7.4 32.8 0.39 11.1 2.5 4.2 1 1 4 5 5 5 0 Centromere protein H (CENP-H) DUF573 PF04504.14 KFQ94689.1 - 5.7 7.7 9.1 4.8 7.9 0.5 3.9 2 2 2 4 4 4 0 Protein of unknown function, DUF573 TACC_C PF05010.14 KFQ94689.1 - 6.9 6.4 37.6 0.58 9.9 7.7 2.3 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Fib_alpha PF08702.10 KFQ94689.1 - 7.3 6.8 29.0 0.4 10.9 6.0 3.7 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family WXG100 PF06013.12 KFQ94689.1 - 7.3 6.9 15.4 13 6.1 5.1 3.8 3 1 0 3 3 3 0 Proteins of 100 residues with WXG Peptidase_M18 PF02127.15 KFQ94690.1 - 1.8e-168 560.9 0.0 2.2e-168 560.6 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KFQ94690.1 - 2e-07 30.4 0.0 1.3e-05 24.4 0.0 2.6 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase DnaJ PF00226.31 KFQ94691.1 - 1.7e-27 95.3 4.8 2.4e-27 94.9 4.8 1.2 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 KFQ94691.1 - 0.051 13.5 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 A repeated domain in UCH-protein YqgF PF14639.6 KFQ94691.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 Tubulin PF00091.25 KFQ94692.1 - 1.8e-65 220.8 0.0 2.4e-65 220.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFQ94692.1 - 5e-52 175.3 0.0 1.1e-51 174.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFQ94692.1 - 0.0012 18.6 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 KFQ94694.1 - 5.1e-64 216.1 0.0 6.9e-64 215.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFQ94694.1 - 4.5e-52 175.5 0.0 1.1e-51 174.3 0.0 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFQ94694.1 - 0.026 14.2 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Pkinase PF00069.25 KFQ94697.1 - 1.8e-42 145.5 0.0 2.4e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ94697.1 - 3.3e-25 88.8 0.0 4.1e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ94697.1 - 5.7e-05 22.6 0.0 7.2e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFQ94697.1 - 0.00046 19.6 0.1 0.0008 18.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFQ94697.1 - 0.00059 19.8 0.4 0.078 12.9 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Glyco_hydro_35 PF01301.19 KFQ94698.1 - 2.6e-101 339.4 0.0 3.1e-101 339.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KFQ94698.1 - 3e-09 37.5 0.0 1.5e-08 35.2 0.0 2.2 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Glyco_hydro_42 PF02449.15 KFQ94698.1 - 7.5e-09 35.4 0.0 9.6e-08 31.7 0.0 2.0 1 1 0 1 1 1 1 Beta-galactosidase bVLRF1 PF18826.1 KFQ94699.1 - 7.5e-53 178.4 0.0 1.4e-52 177.5 0.0 1.5 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor VATC PF18716.1 KFQ94699.1 - 4e-19 68.2 2.6 4e-19 68.2 2.6 2.3 2 0 0 2 2 2 1 Vms1-associating treble clef domain Ank_5 PF13857.6 KFQ94699.1 - 2.5e-08 34.0 0.1 5.4e-07 29.8 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFQ94699.1 - 5.2e-06 27.0 0.0 2.3e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFQ94699.1 - 3.4e-05 23.9 0.1 0.00012 22.2 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 KFQ94699.1 - 4.2e-05 23.8 0.3 0.00011 22.4 0.3 1.7 1 0 0 1 1 1 1 Ankyrin repeat zf-FCS PF06467.14 KFQ94699.1 - 0.033 14.1 11.6 2 8.5 0.4 3.5 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Ank_4 PF13637.6 KFQ94699.1 - 0.037 14.6 0.0 0.36 11.5 0.0 2.4 2 1 1 3 3 3 0 Ankyrin repeats (many copies) zf_UBZ PF18439.1 KFQ94699.1 - 0.16 11.6 2.6 0.49 10.0 1.5 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2 PF00096.26 KFQ94699.1 - 6.7 7.4 11.6 0.55 10.8 1.2 3.1 2 1 0 2 2 2 0 Zinc finger, C2H2 type APG9 PF04109.16 KFQ94700.1 - 4.4e-172 573.4 12.0 5.4e-172 573.1 12.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 EMP24_GP25L PF01105.24 KFQ94700.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD MTABC_N PF16185.5 KFQ94701.1 - 1.4e-41 142.6 4.5 3.5e-41 141.3 4.5 1.7 1 0 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region ABC_membrane PF00664.23 KFQ94701.1 - 4.7e-39 134.7 11.4 7.4e-39 134.0 11.4 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFQ94701.1 - 1.2e-34 119.7 0.0 2.1e-34 119.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFQ94701.1 - 1.1e-06 28.2 0.1 8.6e-05 22.1 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFQ94701.1 - 2.9e-05 24.5 0.1 6.2e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFQ94701.1 - 0.00053 20.3 0.0 0.0046 17.2 0.0 2.4 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 KFQ94701.1 - 0.0028 17.6 0.0 0.0055 16.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KFQ94701.1 - 0.0031 17.2 0.0 0.0076 16.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 KFQ94701.1 - 0.0085 16.5 0.0 0.13 12.7 0.0 2.4 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 KFQ94701.1 - 0.0088 15.9 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KFQ94701.1 - 0.015 15.5 0.3 0.32 11.3 0.3 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 KFQ94701.1 - 0.018 14.8 0.0 0.055 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Acyl-CoA_dh_1 PF00441.24 KFQ94701.1 - 0.026 14.8 0.1 0.079 13.2 0.0 1.8 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Zeta_toxin PF06414.12 KFQ94701.1 - 0.05 12.9 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 KFQ94701.1 - 0.053 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFQ94701.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 KFQ94701.1 - 0.06 13.3 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Cytidylate_kin PF02224.18 KFQ94701.1 - 0.072 12.8 0.1 0.31 10.8 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase AAA_5 PF07728.14 KFQ94701.1 - 0.083 12.9 0.2 0.65 10.0 0.0 2.4 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KFQ94701.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) zf-AN1 PF01428.16 KFQ94702.1 - 6.3e-21 74.2 26.5 9.6e-13 48.1 10.6 2.8 2 1 1 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 KFQ94702.1 - 0.086 13.2 16.4 0.93 9.9 2.2 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zinc_ribbon_4 PF13717.6 KFQ94702.1 - 0.19 11.7 9.8 0.33 10.9 1.6 3.4 3 0 0 3 3 3 0 zinc-ribbon domain IBR PF01485.21 KFQ94702.1 - 4.6 7.5 25.7 1.2 9.4 11.6 3.1 1 1 1 3 3 3 0 IBR domain, a half RING-finger domain zinc-ribbons_6 PF07191.12 KFQ94702.1 - 9.4 6.3 19.0 1 9.4 3.3 2.4 2 0 0 2 2 2 0 zinc-ribbons Reticulon PF02453.17 KFQ94703.1 - 0.2 11.6 0.8 0.36 10.8 0.8 1.3 1 0 0 1 1 1 0 Reticulon Cyclin PF08613.11 KFQ94704.1 - 1.4e-07 32.0 0.0 1.9e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KFQ94704.1 - 3.2e-06 26.9 0.0 4.3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Xan_ur_permease PF00860.20 KFQ94705.1 - 2.5e-64 217.4 17.9 4.5e-64 216.6 17.9 1.4 1 1 0 1 1 1 1 Permease family Bap31 PF05529.12 KFQ94705.1 - 0.14 12.0 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region XLF PF09302.11 KFQ94706.1 - 4.3e-36 124.8 0.0 6.5e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF3583 PF12126.8 KFQ94706.1 - 0.02 14.4 1.3 0.033 13.6 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) Patatin PF01734.22 KFQ94706.1 - 0.15 12.2 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Patatin-like phospholipase Hint PF01079.20 KFQ94708.1 - 6.4e-73 244.8 0.0 7.7e-73 244.5 0.0 1.1 1 0 0 1 1 1 1 Hint module HH_signal PF01085.18 KFQ94708.1 - 1.1e-49 168.2 0.3 1.5e-49 167.8 0.3 1.2 1 0 0 1 1 1 1 Hedgehog amino-terminal signalling domain Peptidase_M15_3 PF08291.11 KFQ94708.1 - 0.00043 20.3 0.0 0.00067 19.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase M15 Homeodomain PF00046.29 KFQ94709.1 - 1.8e-22 79.0 7.2 2.6e-22 78.4 7.2 1.3 1 0 0 1 1 1 1 Homeodomain QLQ PF08880.11 KFQ94709.1 - 0.001 18.8 0.4 0.0015 18.2 0.4 1.3 1 0 0 1 1 1 1 QLQ ASH PF15780.5 KFQ94710.1 - 2.7e-36 123.7 0.6 1.3e-06 28.5 0.0 9.3 9 0 0 9 9 9 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 KFQ94710.1 - 1e-17 63.9 0.0 0.08 12.8 0.0 8.6 10 0 0 10 10 10 6 MSP (Major sperm protein) domain TMEM131_like PF12371.8 KFQ94710.1 - 9.5e-08 32.2 0.1 0.13 12.6 0.0 5.3 4 0 0 4 4 4 3 Transmembrane protein 131-like PapD-like PF14874.6 KFQ94710.1 - 4.2e-06 26.9 0.9 0.43 10.8 0.0 6.1 6 0 0 6 6 6 1 Flagellar-associated PapD-like Crystall PF00030.19 KFQ94711.1 - 1e-56 189.1 5.5 9e-28 96.3 0.7 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin IL4_i_Ig PF18258.1 KFQ94711.1 - 0.00026 21.2 2.4 0.37 11.0 0.3 3.6 2 2 2 4 4 4 3 Interleukin-4 inducing immunoglobulin-binding domain Inhibitor_I36 PF03995.13 KFQ94711.1 - 0.00056 19.8 0.3 0.053 13.5 0.4 2.7 2 1 0 2 2 2 2 Peptidase inhibitor family I36 Ets PF00178.22 KFQ94712.1 - 2.2e-36 124.2 0.4 3e-36 123.7 0.4 1.2 1 0 0 1 1 1 1 Ets-domain wnt PF00110.19 KFQ94713.1 - 2.9e-123 411.4 18.6 3.3e-123 411.2 18.6 1.0 1 0 0 1 1 1 1 wnt family p450 PF00067.22 KFQ94714.1 - 9.9e-100 334.5 0.0 1.2e-99 334.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TTL PF03133.15 KFQ94715.1 - 2.4e-101 338.8 0.1 3.6e-101 338.2 0.1 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KFQ94715.1 - 2.9e-06 26.7 0.1 0.00031 20.1 0.0 2.9 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KFQ94715.1 - 0.0013 18.1 0.0 0.012 14.9 0.0 2.1 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp RWD PF05773.22 KFQ94716.1 - 2.9e-13 50.1 0.1 6.8e-13 48.9 0.1 1.6 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 KFQ94716.1 - 2e-06 28.0 7.6 1.6e-05 25.1 7.7 2.3 1 1 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFQ94716.1 - 6e-06 25.9 5.1 6e-06 25.9 5.1 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KFQ94716.1 - 2.9e-05 23.9 6.7 6.9e-05 22.7 6.7 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFQ94716.1 - 0.0041 16.9 7.4 0.0062 16.4 3.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ94716.1 - 0.0085 15.9 4.9 0.086 12.7 5.3 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFQ94716.1 - 0.018 15.0 6.9 0.024 14.7 1.0 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.7 KFQ94716.1 - 0.04 14.2 2.2 0.04 14.2 2.2 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFQ94716.1 - 0.04 14.0 2.3 0.17 12.0 0.6 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zf_RING PF16744.5 KFQ94716.1 - 0.45 10.7 3.9 1.2 9.3 3.9 1.6 1 1 0 1 1 1 0 KIAA1045 RING finger BCS1_N PF08740.11 KFQ94717.1 - 1.4e-45 155.6 3.1 2e-45 155.1 3.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KFQ94717.1 - 3.4e-20 72.8 0.0 5.5e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KFQ94717.1 - 0.00033 21.0 0.0 0.0028 18.0 0.0 2.4 2 1 0 2 2 2 1 RNA helicase AAA_16 PF13191.6 KFQ94717.1 - 0.00096 19.6 0.2 0.0044 17.4 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KFQ94717.1 - 0.0041 16.3 0.0 0.0075 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 KFQ94717.1 - 0.0084 16.6 0.0 0.015 15.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Rad17 PF03215.15 KFQ94717.1 - 0.0088 16.0 0.0 0.034 14.1 0.0 1.8 1 1 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 KFQ94717.1 - 0.015 15.3 0.0 0.035 14.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KFQ94717.1 - 0.032 14.4 0.0 0.077 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KFQ94717.1 - 0.041 13.5 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Polyoma_lg_T_C PF06431.11 KFQ94717.1 - 0.042 12.7 0.0 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus AAA_29 PF13555.6 KFQ94717.1 - 0.046 13.5 0.1 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 KFQ94717.1 - 0.077 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KFQ94717.1 - 0.094 13.3 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KFQ94717.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KFQ94717.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KFQ94717.1 - 0.15 11.5 0.0 0.39 10.2 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 KFQ94717.1 - 0.15 12.3 0.0 0.96 9.7 0.0 2.3 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 KFQ94717.1 - 0.16 11.8 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 KFQ94717.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain zf-H2C2_2 PF13465.6 KFQ94718.1 - 3.5e-41 137.8 325.8 5.1e-06 26.7 2.7 37.7 40 0 0 40 40 40 22 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFQ94718.1 - 1.6e-29 101.3 270.9 2.1e-06 27.4 0.5 32.4 33 0 0 33 33 33 22 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFQ94718.1 - 4.4e-24 83.5 371.7 0.00031 21.0 1.4 39.7 40 0 0 40 40 40 26 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ94718.1 - 1.7e-18 65.7 357.1 0.0016 19.1 1.4 39.7 40 0 0 40 40 40 22 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFQ94718.1 - 2.6e-06 27.3 6.1 0.00011 22.2 0.6 21.5 24 4 1 25 25 25 7 C2H2-type zinc finger Rcd1 PF04078.13 KFQ94719.1 - 1.2e-134 447.6 0.8 1.3e-134 447.4 0.8 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like UCH PF00443.29 KFQ94720.1 - 3.1e-58 197.3 0.9 5.5e-58 196.5 0.9 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_N PF16674.5 KFQ94720.1 - 5.2e-44 148.5 0.0 1.1e-43 147.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal of ubiquitin carboxyl-terminal hydrolase 37 UCH_1 PF13423.6 KFQ94720.1 - 7.1e-12 45.5 19.8 5.4e-09 36.1 19.8 3.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UIM PF02809.20 KFQ94720.1 - 2.1e-08 33.5 20.7 0.00025 20.7 0.2 3.9 3 0 0 3 3 3 3 Ubiquitin interaction motif Peptidase_C98 PF15499.6 KFQ94720.1 - 0.058 12.9 6.5 0.35 10.3 3.4 3.1 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Elongin_A PF06881.11 KFQ94720.1 - 1.8 9.1 11.3 0.38 11.3 6.8 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Gelsolin PF00626.22 KFQ94721.1 - 6.5e-105 343.2 0.0 2e-19 69.2 0.0 6.3 6 0 0 6 6 6 6 Gelsolin repeat VHP PF02209.19 KFQ94721.1 - 7.9e-16 57.8 0.5 1.8e-15 56.7 0.5 1.6 1 0 0 1 1 1 1 Villin headpiece domain NIF PF03031.18 KFQ94722.1 - 9.2e-44 149.0 0.0 1e-43 148.8 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Nramp PF01566.18 KFQ94723.1 - 1.7e-116 389.1 14.3 1.7e-116 389.1 14.3 1.5 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein Lactamase_B PF00753.27 KFQ94725.1 - 0.0036 17.3 0.0 0.008 16.2 0.0 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Bax1-I PF01027.20 KFQ94726.1 - 4.6e-25 88.7 27.3 1.8e-24 86.7 27.3 1.7 1 1 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 KFQ94726.1 - 0.18 11.4 16.3 0.028 14.0 9.3 2.0 2 0 0 2 2 2 0 Bax inhibitor 1 like DUF2070 PF09843.9 KFQ94726.1 - 0.18 10.1 10.2 0.25 9.6 10.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2157 PF09925.9 KFQ94726.1 - 1.3 8.8 8.4 3.3 7.5 8.4 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Wzy_C PF04932.15 KFQ94726.1 - 2.8 7.6 10.1 1.8 8.2 0.1 3.1 2 1 1 3 3 3 0 O-Antigen ligase WD40 PF00400.32 KFQ94727.1 - 1.3e-29 101.8 15.8 1.3e-05 25.8 0.2 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ94727.1 - 3.1e-20 72.2 1.5 1.9e-06 28.0 0.0 5.5 1 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFQ94727.1 - 6.9e-08 32.6 0.2 0.02 14.8 0.1 3.7 2 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KFQ94727.1 - 3.5e-05 23.3 0.0 0.31 10.3 0.0 2.9 3 0 0 3 3 3 2 WD40-like domain PQQ_2 PF13360.6 KFQ94727.1 - 0.0021 17.7 0.3 0.026 14.1 0.1 2.4 1 1 1 2 2 2 1 PQQ-like domain PQQ PF01011.21 KFQ94727.1 - 0.011 15.7 3.7 1.5 8.9 0.0 4.4 4 0 0 4 4 4 0 PQQ enzyme repeat Nup160 PF11715.8 KFQ94727.1 - 0.02 13.6 0.0 0.5 9.0 0.0 2.5 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFQ94727.1 - 0.11 11.5 0.2 1.3 7.9 0.0 2.7 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein P34-Arc PF04045.14 KFQ94728.1 - 4.4e-105 350.7 1.5 5.2e-105 350.5 1.5 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Vps4_C PF09336.10 KFQ94728.1 - 0.033 14.2 0.2 1.1 9.3 0.1 3.0 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain ARPC4 PF05856.12 KFQ94728.1 - 0.034 13.8 0.1 0.086 12.4 0.0 1.7 2 0 0 2 2 2 0 ARP2/3 complex 20 kDa subunit (ARPC4) Calici_coat PF00915.20 KFQ94728.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Calicivirus coat protein RUN PF02759.19 KFQ94729.1 - 1.1e-11 44.8 0.2 1.2e-11 44.6 0.2 1.0 1 0 0 1 1 1 1 RUN domain SH2 PF00017.24 KFQ94731.1 - 2.3e-21 75.7 0.0 4.7e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 SH2 domain PH PF00169.29 KFQ94731.1 - 8.2e-09 35.9 0.4 4.7e-08 33.5 0.2 2.0 2 0 0 2 2 2 1 PH domain SH3_1 PF00018.28 KFQ94731.1 - 4.5e-06 26.2 0.2 8.5e-06 25.3 0.2 1.5 1 0 0 1 1 1 1 SH3 domain PH_11 PF15413.6 KFQ94731.1 - 0.015 15.7 0.2 0.029 14.8 0.2 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain SH3_9 PF14604.6 KFQ94731.1 - 0.047 13.5 0.1 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 Variant SH3 domain THF_DHG_CYH PF00763.23 KFQ94731.1 - 0.2 11.9 0.5 11 6.3 0.0 2.2 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain ubiquitin PF00240.23 KFQ94732.1 - 1.3e-14 53.7 0.0 1.4e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 KFQ94732.1 - 0.018 15.2 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like RAWUL PF16207.5 KFQ94734.1 - 5.6e-12 46.2 0.9 1.1e-11 45.2 0.3 1.8 2 0 0 2 2 2 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-RING_2 PF13639.6 KFQ94734.1 - 0.0093 16.3 3.6 0.0093 16.3 3.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFQ94734.1 - 0.0096 15.7 3.4 0.0096 15.7 3.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFQ94734.1 - 0.011 15.6 2.8 0.011 15.6 2.8 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GAGA PF09237.11 KFQ94734.1 - 0.027 14.3 0.1 0.077 12.8 0.1 1.7 1 0 0 1 1 1 0 GAGA factor zf-rbx1 PF12678.7 KFQ94734.1 - 0.074 13.4 0.6 0.074 13.4 0.6 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KFQ94734.1 - 0.15 11.9 5.0 0.3 10.9 2.2 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KFQ94734.1 - 0.66 9.9 5.3 0.32 10.9 1.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF3337 PF11816.8 KFQ94734.1 - 1.1 9.1 5.3 29 4.5 5.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3337) zf-C3HC4 PF00097.25 KFQ94734.1 - 3.9 7.4 10.3 0.34 10.8 4.7 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFQ94734.1 - 4.7 7.2 7.6 0.9 9.5 2.9 2.2 2 0 0 2 2 2 0 zinc-RING finger domain MDD_C PF18376.1 KFQ94735.1 - 4.1e-64 215.8 0.0 4.6e-64 215.6 0.0 1.0 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain Ras PF00071.22 KFQ94736.1 - 1.1e-08 34.8 0.0 1.2e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Ras family HIF-1a_CTAD PF08778.10 KFQ94738.1 - 1.6e-22 78.8 0.6 3.8e-22 77.6 0.6 1.7 1 0 0 1 1 1 1 HIF-1 alpha C terminal transactivation domain PAS_3 PF08447.12 KFQ94738.1 - 3.3e-20 72.2 0.1 5.7e-20 71.4 0.1 1.4 1 0 0 1 1 1 1 PAS fold HIF-1 PF11413.8 KFQ94738.1 - 7.3e-16 57.3 5.2 1.8e-15 56.0 5.2 1.7 1 0 0 1 1 1 1 Hypoxia-inducible factor-1 PAS_11 PF14598.6 KFQ94738.1 - 7.8e-16 58.2 0.0 2.1e-15 56.9 0.0 1.7 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KFQ94738.1 - 4e-06 26.8 0.0 8.4e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KFQ94738.1 - 0.00012 22.2 0.0 0.0004 20.6 0.0 1.8 2 0 0 2 2 2 1 PAS domain SNAPc_SNAP43 PF09808.9 KFQ94739.1 - 2.5e-45 154.8 3.9 2.5e-45 154.8 3.9 1.6 2 0 0 2 2 2 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 DUF4539 PF15072.6 KFQ94739.1 - 0.15 12.2 0.1 24 5.0 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4539) C2 PF00168.30 KFQ94740.1 - 1.2e-18 67.2 0.0 6.7e-10 39.2 0.0 2.2 2 0 0 2 2 2 2 C2 domain UPF0730 PF15827.5 KFQ94741.1 - 1.7e-27 94.9 8.0 3.3e-27 93.9 8.0 1.5 1 0 0 1 1 1 1 UPF0730 unknown protein family SERTA PF06031.13 KFQ94741.1 - 3e-14 52.4 2.4 4.5e-14 51.8 2.4 1.3 1 0 0 1 1 1 1 SERTA motif Ion_trans PF00520.31 KFQ94742.1 - 2.7e-36 125.0 10.2 3.7e-36 124.6 10.2 1.2 1 0 0 1 1 1 1 Ion transport protein PAS_9 PF13426.7 KFQ94742.1 - 8.7e-17 61.3 0.0 2.6e-16 59.7 0.0 1.9 1 0 0 1 1 1 1 PAS domain Ion_trans_2 PF07885.16 KFQ94742.1 - 5.2e-13 48.8 2.7 5.2e-13 48.8 2.7 2.0 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 KFQ94742.1 - 5.6e-13 48.8 0.0 1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PAS PF00989.25 KFQ94742.1 - 5.1e-07 29.7 0.0 1.5e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 KFQ94742.1 - 0.00019 21.7 0.0 0.00039 20.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold NPV_P10 PF05531.12 KFQ94742.1 - 0.0085 16.5 1.8 0.029 14.8 1.8 1.9 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Cupin_2 PF07883.11 KFQ94742.1 - 0.012 15.3 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Cupin domain PAS_4 PF08448.10 KFQ94742.1 - 0.015 15.5 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 PAS fold Cupin_3 PF05899.12 KFQ94742.1 - 0.055 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Ras PF00071.22 KFQ94743.1 - 1.4e-48 164.6 0.0 1.6e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ94743.1 - 1.4e-18 67.2 0.0 2.1e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ94743.1 - 2.5e-05 23.8 0.0 3.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family TniB PF05621.11 KFQ94743.1 - 0.087 12.2 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Cys_knot PF00007.22 KFQ94744.1 - 1.5e-17 63.8 7.6 1.9e-17 63.5 7.6 1.1 1 0 0 1 1 1 1 Cystine-knot domain DAN PF03045.15 KFQ94744.1 - 0.0032 17.5 1.8 0.0048 16.9 1.8 1.3 1 0 0 1 1 1 1 DAN domain B56 PF01603.20 KFQ94745.1 - 1.5e-176 587.5 9.2 1.7e-176 587.3 9.2 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KFQ94745.1 - 0.081 12.8 4.4 0.76 9.7 0.7 3.0 3 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal SBF2 PF12335.8 KFQ94745.1 - 0.085 12.5 0.0 0.21 11.2 0.0 1.6 2 0 0 2 2 2 0 Myotubularin protein HAD_2 PF13419.6 KFQ94745.1 - 0.1 12.6 0.2 0.84 9.7 0.1 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase WD40 PF00400.32 KFQ94746.1 - 2.1e-11 44.2 13.7 0.019 15.8 0.0 6.5 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ94746.1 - 4.2e-06 27.0 0.1 0.47 10.8 0.0 4.6 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KFQ94746.1 - 0.0095 14.7 0.0 0.17 10.6 0.0 2.3 1 1 0 2 2 2 1 Nup133 N terminal like PAP2 PF01569.21 KFQ94747.1 - 2.1e-15 56.7 7.0 5.6e-15 55.3 7.0 1.7 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KFQ94747.1 - 1.3e-05 25.0 8.9 4.6e-05 23.2 8.9 2.0 1 1 0 1 1 1 1 PAP2 superfamily ERbeta_N PF12497.8 KFQ94748.1 - 3.9e-53 178.1 8.7 6.6e-53 177.3 8.7 1.4 1 0 0 1 1 1 1 Estrogen receptor beta Hormone_recep PF00104.30 KFQ94748.1 - 1.7e-34 119.2 1.4 2.6e-34 118.6 1.4 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFQ94748.1 - 1.7e-31 108.4 13.4 3.5e-31 107.5 13.4 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) FTHFS PF01268.19 KFQ94749.1 - 2.3e-260 864.6 0.0 3e-260 864.2 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KFQ94749.1 - 5e-67 224.2 1.3 5e-67 224.2 1.3 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KFQ94749.1 - 2.1e-32 111.8 0.1 5e-32 110.6 0.1 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain BTB PF00651.31 KFQ94751.1 - 7.7e-20 71.2 1.6 7.7e-20 71.2 1.6 2.0 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2_4 PF13894.6 KFQ94751.1 - 4e-11 42.8 60.8 0.14 13.0 0.1 10.3 9 0 0 9 9 9 6 C2H2-type zinc finger zf-C2H2 PF00096.26 KFQ94751.1 - 3.5e-08 33.5 64.1 0.036 14.5 0.1 10.4 10 0 0 10 10 10 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ94751.1 - 0.00071 19.9 2.6 0.00071 19.9 2.6 8.6 9 1 0 9 9 8 3 Zinc-finger double domain zf_UBZ PF18439.1 KFQ94751.1 - 0.0069 16.0 39.6 0.094 12.3 0.1 8.8 8 1 1 9 9 9 3 Ubiquitin-Binding Zinc Finger zf-C2H2_8 PF15909.5 KFQ94751.1 - 0.027 14.8 25.4 0.9 9.9 0.1 5.2 4 1 1 5 5 5 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KFQ94751.1 - 0.027 14.8 0.2 0.027 14.8 0.2 8.3 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFQ94751.1 - 0.029 14.8 43.0 0.047 14.1 0.4 9.3 8 1 0 8 8 8 0 Zinc-finger of C2H2 type CpXC PF14353.6 KFQ94751.1 - 0.03 14.3 21.8 3.1 7.9 3.0 5.7 3 1 2 5 5 5 0 CpXC protein zf-Di19 PF05605.12 KFQ94751.1 - 0.39 11.1 44.2 0.078 13.3 3.1 7.7 3 2 5 8 8 8 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 KFQ94751.1 - 4.1 7.3 11.7 8.2 6.4 0.1 5.0 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) HSP70 PF00012.20 KFQ94752.1 - 3.5e-263 874.3 10.7 4e-263 874.1 10.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFQ94752.1 - 2.1e-17 63.0 0.7 7.9e-16 57.8 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KFQ94752.1 - 0.00062 19.5 0.0 0.0017 18.1 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KFQ94752.1 - 0.00078 19.8 2.7 1.5 9.3 0.0 3.6 3 1 0 3 3 3 2 Cell division protein FtsA CRIC_ras_sig PF10534.9 KFQ94752.1 - 0.0028 17.8 0.1 0.01 16.0 0.1 2.0 1 1 1 2 2 2 1 Connector enhancer of kinase suppressor of ras Hydantoinase_A PF01968.18 KFQ94752.1 - 0.027 13.8 1.6 0.085 12.1 0.2 2.3 2 1 0 2 2 2 0 Hydantoinase/oxoprolinase SHS2_FTSA PF02491.20 KFQ94752.1 - 0.11 12.9 1.6 8.8 6.8 0.4 2.7 2 0 0 2 2 2 0 SHS2 domain inserted in FTSA TFIIB PF00382.19 KFQ94753.1 - 1.9e-32 111.1 0.0 6e-16 58.2 0.0 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KFQ94753.1 - 5e-27 94.2 11.0 5e-27 94.2 11.0 3.0 3 0 0 3 3 3 1 Brf1-like TBP-binding domain Cyclin_N PF00134.23 KFQ94753.1 - 1e-07 31.7 0.2 0.0006 19.6 0.1 2.6 2 0 0 2 2 2 2 Cyclin, N-terminal domain RB_B PF01857.20 KFQ94753.1 - 0.0017 18.4 0.2 0.0048 16.9 0.2 1.7 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain TFIIB_C_1 PF18542.1 KFQ94753.1 - 0.04 14.0 0.0 0.23 11.5 0.0 2.2 2 0 0 2 2 2 0 Transcription factor IIB C-terminal module 1 SNAD2 PF18745.1 KFQ94753.1 - 0.11 12.1 1.9 0.26 11.0 1.9 1.5 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 2 PHR PF08005.12 KFQ94754.1 - 1.5e-44 152.3 1.3 2.5e-44 151.6 1.3 1.4 1 0 0 1 1 1 1 PHR domain BTB PF00651.31 KFQ94754.1 - 1.1e-24 86.8 0.1 1.4e-23 83.2 0.0 2.3 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFQ94754.1 - 9.2e-08 32.1 3.3 1.3e-07 31.6 1.3 2.3 2 1 0 2 2 2 1 BTB And C-terminal Kelch DUF4082 PF13313.6 KFQ94754.1 - 0.0017 18.4 0.1 0.0035 17.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4082) NUDIX PF00293.28 KFQ94756.1 - 0.00027 21.0 0.1 0.0019 18.3 0.1 1.9 1 1 0 1 1 1 1 NUDIX domain ESPR PF13018.6 KFQ94756.1 - 0.064 13.1 0.3 0.13 12.1 0.3 1.5 1 0 0 1 1 1 0 Extended Signal Peptide of Type V secretion system EGF PF00008.27 KFQ94757.1 - 7.2e-77 253.2 286.4 5.1e-09 36.3 6.5 18.7 20 0 0 20 20 20 15 EGF-like domain hEGF PF12661.7 KFQ94757.1 - 3.3e-45 151.2 244.5 7.7e-06 26.4 7.5 20.5 22 0 0 22 22 22 14 Human growth factor-like EGF MNNL PF07657.13 KFQ94757.1 - 6.6e-27 93.4 1.3 6.6e-27 93.4 1.3 6.6 8 2 0 8 8 8 1 N terminus of Notch ligand DSL PF01414.19 KFQ94757.1 - 2.3e-24 85.4 5.9 2.3e-24 85.4 5.9 13.5 10 3 3 13 13 13 3 Delta serrate ligand EGF_2 PF07974.13 KFQ94757.1 - 1.5e-18 66.8 322.3 0.00053 20.3 7.4 20.2 20 0 0 20 20 20 13 EGF-like domain EGF_CA PF07645.15 KFQ94757.1 - 4.1e-05 23.7 24.7 0.00044 20.4 10.4 19.8 9 4 11 20 20 20 10 Calcium-binding EGF domain HSA PF07529.13 KFQ94758.1 - 9.3e-23 80.3 15.3 9.3e-23 80.3 15.3 2.2 1 1 1 2 2 2 1 HSA NAD_binding_5 PF07994.12 KFQ94758.1 - 0.087 12.2 3.1 0.096 12.1 3.1 1.1 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase DUF2009 PF09418.10 KFQ94758.1 - 0.19 10.8 9.7 0.21 10.6 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) NAT PF04768.13 KFQ94758.1 - 0.26 10.9 5.7 0.33 10.6 2.8 2.0 1 1 1 2 2 2 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase DBINO PF13892.6 KFQ94758.1 - 0.31 11.4 30.9 2.1 8.7 30.9 1.9 1 1 0 1 1 1 0 DNA-binding domain Ndc1_Nup PF09531.10 KFQ94758.1 - 1.1 7.9 5.8 1.2 7.8 5.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CorA PF01544.18 KFQ94758.1 - 2.5 7.3 11.0 3 7.1 11.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Rgp1 PF08737.10 KFQ94758.1 - 5.4 6.1 11.1 6.6 5.8 11.1 1.0 1 0 0 1 1 1 0 Rgp1 TMEM252 PF15664.5 KFQ94759.1 - 1.7e-38 131.5 0.3 2.1e-38 131.2 0.3 1.1 1 0 0 1 1 1 1 Transmembrane protein 252 family PIRT PF15099.6 KFQ94759.1 - 0.1 12.2 0.4 0.13 11.8 0.4 1.2 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Saf_2TM PF18303.1 KFQ94759.1 - 0.19 11.3 0.3 0.25 10.9 0.3 1.3 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain PGM_PMM_III PF02880.16 KFQ94760.1 - 1.8e-28 99.0 0.0 3.2e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_I PF02878.16 KFQ94760.1 - 2.8e-15 56.2 0.0 4.6e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KFQ94760.1 - 1e-12 48.6 0.0 2.5e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II cobW PF02492.19 KFQ94761.1 - 3.8e-45 153.6 0.1 5.2e-45 153.2 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KFQ94761.1 - 9.9e-20 70.3 0.0 1.7e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 KFQ94761.1 - 3.6e-05 23.4 0.3 0.0017 17.9 0.1 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFQ94761.1 - 0.00011 22.1 0.2 0.12 12.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase KN_motif PF12075.8 KFQ94762.1 - 2.9e-20 71.8 0.3 6.6e-20 70.6 0.3 1.7 1 0 0 1 1 1 1 KN motif CCD48 PF15799.5 KFQ94762.1 - 0.98 7.7 4.1 0.99 7.6 1.2 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 48 Dmrt1 PF12374.8 KFQ94764.1 - 2.9e-29 101.3 6.0 2.9e-29 101.3 6.0 2.0 2 1 0 2 2 2 1 Double-sex mab3 related transcription factor 1 Ustilago_mating PF05722.12 KFQ94764.1 - 0.024 14.2 0.5 0.03 13.9 0.5 1.1 1 0 0 1 1 1 0 Ustilago B locus mating-type protein BDV_P40 PF06407.11 KFQ94764.1 - 0.072 12.2 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 Borna disease virus P40 protein DMA PF03474.14 KFQ94765.1 - 8.6e-17 60.4 0.1 1.3e-16 59.8 0.1 1.3 1 0 0 1 1 1 1 DMRTA motif DUF4490 PF14892.6 KFQ94766.1 - 0.015 15.3 0.3 0.038 14.0 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4490) Ldl_recept_a PF00057.18 KFQ94767.1 - 5.7e-101 330.4 150.2 3.8e-14 52.6 13.4 8.6 8 0 0 8 8 8 8 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 KFQ94767.1 - 1.9e-57 191.5 5.2 4.6e-15 55.8 0.0 5.5 5 0 0 5 5 5 5 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 KFQ94767.1 - 5e-20 71.5 32.7 3.7e-10 39.9 5.2 6.2 5 1 0 5 5 5 3 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 KFQ94767.1 - 5.3e-08 32.9 5.5 5.3e-08 32.9 5.5 10.9 6 3 1 7 7 7 2 Calcium-binding EGF domain SGL PF08450.12 KFQ94767.1 - 2.1e-07 30.8 0.5 0.018 14.6 0.1 3.4 1 1 3 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region cEGF PF12662.7 KFQ94767.1 - 2.5e-06 27.3 23.1 0.039 13.9 0.9 6.0 4 1 0 4 4 4 3 Complement Clr-like EGF-like EGF PF00008.27 KFQ94767.1 - 4.3e-05 23.7 15.7 0.00047 20.4 3.5 9.8 8 1 1 9 9 9 3 EGF-like domain hEGF PF12661.7 KFQ94767.1 - 0.023 15.3 0.9 0.023 15.3 0.9 11.6 9 4 3 12 12 12 0 Human growth factor-like EGF Arylesterase PF01731.20 KFQ94767.1 - 0.063 13.5 0.0 3.2 8.0 0.0 2.9 3 0 0 3 3 3 0 Arylesterase CPL PF08144.11 KFQ94768.1 - 9.6e-49 165.4 0.0 9.6e-49 165.4 0.0 4.0 5 1 0 5 5 5 1 CPL (NUC119) domain PUF PF00806.19 KFQ94768.1 - 0.0058 16.3 0.9 4.7 7.1 0.1 4.1 5 0 0 5 5 5 2 Pumilio-family RNA binding repeat Arm-DNA-bind_2 PF12167.8 KFQ94768.1 - 0.047 13.6 0.0 0.18 11.7 0.0 2.0 1 0 0 1 1 1 0 Arm DNA-binding domain PsbI PF02532.14 KFQ94769.1 - 9.9 6.2 8.7 0.18 11.8 1.3 1.9 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) CARM1 PF11531.8 KFQ94770.1 - 2e-23 82.7 1.4 3.9e-23 81.8 1.4 1.5 1 0 0 1 1 1 1 Coactivator-associated arginine methyltransferase 1 N terminal PrmA PF06325.13 KFQ94770.1 - 6.9e-10 38.8 0.0 1.1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KFQ94770.1 - 7.9e-10 39.3 0.0 1.9e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFQ94770.1 - 2.7e-08 34.4 0.0 7.7e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KFQ94770.1 - 2.2e-07 30.1 0.0 3.7e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 KFQ94770.1 - 1.9e-06 27.6 0.0 4.3e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 KFQ94770.1 - 1.1e-05 25.5 0.0 1.9e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFQ94770.1 - 1.9e-05 24.5 0.0 4.1e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFQ94770.1 - 2e-05 24.5 0.0 0.00062 19.6 0.0 2.3 1 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 KFQ94770.1 - 0.00015 21.1 0.1 0.00023 20.5 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PRMT5 PF05185.16 KFQ94770.1 - 0.00021 21.2 0.1 0.00035 20.5 0.1 1.4 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Cons_hypoth95 PF03602.15 KFQ94770.1 - 0.00037 20.2 0.0 0.00082 19.1 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PRMT5_C PF17286.2 KFQ94770.1 - 0.002 18.0 0.2 0.004 17.1 0.2 1.5 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 KFQ94770.1 - 0.003 17.3 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_12 PF08242.12 KFQ94770.1 - 0.0073 17.0 0.0 0.021 15.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KFQ94770.1 - 0.0096 15.4 0.1 0.017 14.5 0.1 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB IL1_propep PF02394.16 KFQ94770.1 - 0.034 15.1 0.4 0.66 10.9 0.6 2.2 2 0 0 2 2 2 0 Interleukin-1 propeptide GidB PF02527.15 KFQ94770.1 - 0.037 13.3 0.0 0.073 12.4 0.0 1.5 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_32 PF13679.6 KFQ94770.1 - 0.065 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RFX1_trans_act PF04589.13 KFQ94771.1 - 1.2e-35 123.1 18.7 1.2e-35 123.1 18.7 2.3 2 0 0 2 2 2 1 RFX1 transcription activation region RFX_DNA_binding PF02257.15 KFQ94771.1 - 1.1e-33 115.6 0.1 3.7e-33 114.0 0.1 1.9 1 0 0 1 1 1 1 RFX DNA-binding domain HisKA PF00512.25 KFQ94771.1 - 0.017 15.1 0.3 0.041 13.9 0.3 1.6 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain Pox_D5 PF03288.16 KFQ94771.1 - 0.064 13.7 0.0 0.19 12.2 0.0 1.8 1 0 0 1 1 1 0 Poxvirus D5 protein-like DUF2258 PF10015.9 KFQ94771.1 - 0.15 12.2 0.3 0.62 10.2 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2258) zf-C2H2 PF00096.26 KFQ94772.1 - 1.4e-17 63.1 22.6 0.00091 19.6 0.8 6.1 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ94772.1 - 1.9e-09 37.5 23.0 5.2e-05 23.5 0.8 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ94772.1 - 1.4e-07 31.7 22.4 0.0071 17.1 0.2 6.1 5 0 0 5 5 5 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFQ94772.1 - 3.7e-07 30.7 14.6 0.14 12.8 0.1 5.4 1 1 4 5 5 5 3 FOXP coiled-coil domain EpoR_lig-bind PF09067.10 KFQ94772.1 - 0.11 12.7 0.2 0.24 11.6 0.2 1.5 1 0 0 1 1 1 0 Erythropoietin receptor, ligand binding zf-C2H2_aberr PF17017.5 KFQ94772.1 - 0.19 11.9 8.7 18 5.4 0.1 4.3 1 1 3 4 4 4 0 Aberrant zinc-finger PcF PF09461.10 KFQ94772.1 - 1.6 9.1 6.4 21 5.6 0.2 4.4 4 0 0 4 4 4 0 Phytotoxin PcF protein zf-C2H2_8 PF15909.5 KFQ94772.1 - 2.9 8.3 17.9 0.067 13.5 1.1 4.5 4 1 1 5 5 5 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KFQ94772.1 - 5.7 7.4 6.9 45 4.5 0.9 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFQ94772.1 - 6.1 7.4 6.7 12 6.5 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Zip PF02535.22 KFQ94773.1 - 3.5e-102 342.1 19.5 9.3e-66 222.3 13.3 5.0 2 2 2 4 4 4 2 ZIP Zinc transporter AAA_6 PF12774.7 KFQ94774.1 - 3.6e-159 529.0 0.4 8.7e-157 521.2 0.0 3.4 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KFQ94774.1 - 1.7e-140 468.6 8.4 1.7e-140 468.6 8.4 4.0 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 KFQ94774.1 - 3.3e-121 404.2 0.0 3.3e-119 397.7 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 KFQ94774.1 - 1.4e-109 365.4 0.5 2.6e-106 354.7 0.1 2.8 2 0 0 2 2 2 2 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KFQ94774.1 - 3.8e-93 310.7 8.0 6.5e-93 309.9 0.5 4.1 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 KFQ94774.1 - 1.8e-83 278.5 0.1 2.7e-81 271.4 0.0 3.3 3 0 0 3 3 2 1 P-loop containing dynein motor region MT PF12777.7 KFQ94774.1 - 2.1e-53 181.6 6.1 2.1e-53 181.6 6.1 2.4 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 KFQ94774.1 - 3.7e-53 179.7 0.3 1.2e-52 178.1 0.0 2.1 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KFQ94774.1 - 2.2e-47 160.0 0.0 3e-44 149.9 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 KFQ94774.1 - 3.5e-39 133.8 0.2 5.4e-38 130.0 0.1 3.2 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KFQ94774.1 - 2.5e-19 69.6 0.0 0.0027 17.7 0.0 6.1 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KFQ94774.1 - 7.6e-18 64.6 0.0 3.4e-17 62.5 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 KFQ94774.1 - 1.3e-06 28.9 1.3 1.7 9.1 0.0 5.6 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFQ94774.1 - 2.8e-06 27.6 0.9 0.28 11.5 0.0 5.2 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 KFQ94774.1 - 0.0018 18.8 0.4 0.18 12.3 0.0 4.0 4 0 0 4 4 3 1 AAA domain AAA_30 PF13604.6 KFQ94774.1 - 0.002 17.9 0.4 3.4 7.4 0.2 3.1 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 KFQ94774.1 - 0.0029 18.0 1.7 7.9 6.9 0.0 4.2 4 0 0 4 4 3 0 RNA helicase AAA_16 PF13191.6 KFQ94774.1 - 0.0048 17.3 0.0 18 5.7 0.0 4.1 4 0 0 4 4 3 0 AAA ATPase domain EF-hand_7 PF13499.6 KFQ94774.1 - 0.012 16.1 0.8 0.079 13.4 0.8 2.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 KFQ94774.1 - 0.014 15.3 1.8 0.057 13.4 1.8 2.1 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 KFQ94774.1 - 0.016 14.7 1.5 0.082 12.5 1.5 2.3 1 0 0 1 1 1 0 EF hand SRP54 PF00448.22 KFQ94774.1 - 0.046 13.3 0.9 1.6 8.3 0.0 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 KFQ94774.1 - 0.048 13.6 0.0 0.5 10.2 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase T2SSE PF00437.20 KFQ94774.1 - 0.064 12.3 0.2 0.39 9.7 0.0 2.4 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_24 PF13479.6 KFQ94774.1 - 0.1 12.3 0.1 20 4.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KFQ94774.1 - 0.14 12.3 0.1 3.7 7.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain EF-hand_8 PF13833.6 KFQ94774.1 - 0.16 11.8 1.2 0.57 10.1 1.2 2.0 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 KFQ94774.1 - 0.19 11.3 0.8 0.54 9.9 0.8 1.8 1 0 0 1 1 1 0 EF hand DUF4349 PF14257.6 KFQ94774.1 - 0.19 11.1 11.7 0.56 9.6 0.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) DUF4407 PF14362.6 KFQ94774.1 - 1.6 8.0 13.2 0.26 10.6 2.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 KFQ94774.1 - 3.4 8.2 12.1 29 5.2 0.0 5.0 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein MbeD_MobD PF04899.12 KFQ94774.1 - 9.2 6.5 13.4 9.8 6.4 0.5 5.2 5 0 0 5 5 5 0 MbeD/MobD like BIR PF00653.21 KFQ94775.1 - 4.1e-22 78.6 3.4 7.7e-22 77.7 3.4 1.5 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 KFQ94775.1 - 0.006 16.6 0.6 0.01 15.9 0.6 1.5 1 0 0 1 1 1 1 C3HC zinc finger-like Pkinase PF00069.25 KFQ94776.1 - 1.8e-68 230.8 0.0 2.2e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ94776.1 - 2e-35 122.3 0.0 2.4e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ94776.1 - 0.0032 16.8 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFQ94776.1 - 0.22 11.4 0.1 0.49 10.3 0.1 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family HECT PF00632.25 KFQ94777.1 - 2e-104 349.4 0.0 3.1e-104 348.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECW_N PF16562.5 KFQ94777.1 - 1.8e-59 198.8 0.0 3.2e-59 198.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 HECW1_helix PF18436.1 KFQ94777.1 - 1.2e-36 124.6 3.1 4.7e-35 119.5 1.0 3.1 3 0 0 3 3 3 1 Helical box domain of E3 ubiquitin-protein ligase HECW1 WW PF00397.26 KFQ94777.1 - 2.1e-17 62.9 0.4 1.8e-09 37.5 0.3 2.5 2 0 0 2 2 2 2 WW domain C2 PF00168.30 KFQ94777.1 - 6.9e-13 48.8 0.0 2e-12 47.3 0.0 1.8 2 0 0 2 2 2 1 C2 domain TPR_8 PF13181.6 KFQ94778.1 - 1.9e-22 77.5 9.9 0.016 15.3 0.0 10.5 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ94778.1 - 2.8e-21 73.9 13.3 0.00011 22.0 0.0 11.8 13 0 0 13 13 11 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ94778.1 - 9.5e-19 66.4 11.6 0.00045 19.9 0.0 10.0 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ94778.1 - 2.6e-12 47.1 16.1 0.035 14.6 0.0 7.9 4 2 3 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ94778.1 - 3.1e-12 46.9 7.8 0.057 14.1 0.6 9.2 9 1 1 10 10 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ94778.1 - 3.8e-12 45.3 10.1 1.5 9.0 0.0 11.0 11 1 1 12 12 12 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ94778.1 - 2e-10 40.8 15.9 0.0012 19.0 0.5 6.1 5 3 2 7 7 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KFQ94778.1 - 2.1e-09 37.4 12.3 3.2 8.8 0.3 10.4 6 3 4 10 10 10 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ94778.1 - 6.8e-09 35.9 24.6 0.0031 17.8 0.7 8.6 7 4 2 9 9 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFQ94778.1 - 2.1e-08 34.2 9.9 0.3 11.8 0.0 9.3 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ94778.1 - 5.6e-08 32.3 5.3 0.0013 18.3 0.0 6.7 7 0 0 7 7 7 1 TPR repeat TPR_9 PF13371.6 KFQ94778.1 - 4.5e-07 29.9 12.7 0.027 14.6 2.2 6.1 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ94778.1 - 1.1e-06 28.5 7.7 0.1 13.0 0.1 7.9 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFQ94778.1 - 0.00024 20.6 7.7 0.73 9.1 0.0 4.9 3 1 2 5 5 5 2 MalT-like TPR region SHNi-TPR PF10516.9 KFQ94778.1 - 0.0048 16.3 0.0 0.026 14.0 0.0 2.3 1 0 0 1 1 1 1 SHNi-TPR TPR_10 PF13374.6 KFQ94778.1 - 0.013 15.3 14.1 6.6 6.8 0.1 7.8 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_20 PF14561.6 KFQ94778.1 - 0.021 15.2 16.9 8.9 6.7 0.0 7.8 7 2 4 11 11 10 0 Tetratricopeptide repeat DUF627 PF04781.12 KFQ94778.1 - 0.083 12.9 1.8 5.2 7.1 0.0 4.5 4 2 2 6 6 6 0 Protein of unknown function (DUF627) Med8 PF10232.9 KFQ94778.1 - 0.14 11.7 9.4 0.016 14.8 2.7 2.1 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 TPR_4 PF07721.14 KFQ94778.1 - 0.16 12.7 7.1 0.46 11.3 0.0 4.9 5 0 0 5 5 3 0 Tetratricopeptide repeat Foie-gras_1 PF11817.8 KFQ94778.1 - 0.37 10.3 7.0 11 5.5 0.7 3.9 3 1 0 3 3 3 0 Foie gras liver health family 1 SAPS PF04499.15 KFQ94778.1 - 7.6 5.2 12.7 13 4.4 8.7 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein DUF4720 PF15846.5 KFQ94779.1 - 1.7e-48 162.5 0.1 1.9e-48 162.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4720) PGAP1 PF07819.13 KFQ94780.1 - 6.2e-78 261.7 0.0 1e-77 261.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 KFQ94780.1 - 0.00048 20.0 0.1 0.00093 19.1 0.0 1.5 2 0 0 2 2 2 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 KFQ94780.1 - 0.0046 17.6 0.0 0.008 16.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KFQ94780.1 - 0.0046 16.5 0.0 0.009 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 KFQ94780.1 - 0.0059 16.3 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFQ94780.1 - 0.028 13.7 0.0 0.055 12.7 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KFQ94780.1 - 0.074 12.9 0.0 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) Peptidase_S9 PF00326.21 KFQ94780.1 - 0.077 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ank_2 PF12796.7 KFQ94781.1 - 2.2e-174 566.5 87.5 1.3e-19 70.6 1.7 14.9 2 2 11 15 15 15 15 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ94781.1 - 6.5e-158 511.3 55.0 2.9e-14 53.2 0.2 22.1 7 5 17 24 24 24 22 Ankyrin repeats (many copies) Ank PF00023.30 KFQ94781.1 - 6.5e-147 472.2 76.3 2.7e-07 30.7 0.1 28.0 28 0 0 28 28 28 25 Ankyrin repeat Ank_3 PF13606.6 KFQ94781.1 - 9.7e-119 372.8 55.7 1.7e-06 27.9 0.4 28.1 28 0 0 28 28 28 23 Ankyrin repeat Ank_5 PF13857.6 KFQ94781.1 - 6.9e-115 373.6 64.9 3.1e-10 40.1 0.3 22.6 7 4 17 24 24 24 23 Ankyrin repeats (many copies) GATase_7 PF13537.6 KFQ94781.1 - 0.03 14.2 0.0 99 2.9 0.0 5.6 6 0 0 6 6 6 0 Glutamine amidotransferase domain Ribosomal_S6 PF01250.17 KFQ94781.1 - 0.053 13.8 0.0 1.3 9.4 0.0 3.3 3 1 1 4 4 4 0 Ribosomal protein S6 Prok-RING_1 PF14446.6 KFQ94781.1 - 6.2 6.8 6.4 5.8 6.9 0.1 4.1 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 SF3b1 PF08920.10 KFQ94782.1 - 4.3e-47 159.5 6.5 4.3e-47 159.5 6.5 4.7 1 1 2 3 3 3 2 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 KFQ94782.1 - 6.3e-08 32.9 5.0 0.031 14.6 0.0 7.1 5 2 4 9 9 9 3 HEAT repeats HEAT PF02985.22 KFQ94782.1 - 1.2e-07 31.3 7.0 1.2 9.5 0.1 8.7 10 0 0 10 10 9 1 HEAT repeat HEAT_EZ PF13513.6 KFQ94782.1 - 2.2e-07 31.2 3.1 0.52 10.9 0.0 7.0 7 1 1 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KFQ94782.1 - 1.9e-05 25.2 0.6 3 8.5 0.0 4.6 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KFQ94782.1 - 0.0014 18.7 8.3 5.6 7.0 0.0 6.3 7 1 1 9 9 9 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KFQ94782.1 - 0.0018 17.9 1.0 3.6 7.1 0.1 3.3 3 0 0 3 3 3 2 CLASP N terminal DUF3385 PF11865.8 KFQ94782.1 - 0.0042 17.0 2.2 4.2 7.3 0.1 4.9 3 1 1 4 4 4 1 Domain of unknown function (DUF3385) UME PF08064.13 KFQ94782.1 - 0.0057 16.5 0.1 6.1 6.8 0.0 5.2 6 1 1 7 7 7 1 UME (NUC010) domain Adaptin_N PF01602.20 KFQ94782.1 - 0.0083 14.7 1.8 0.13 10.7 1.8 2.8 1 1 0 1 1 1 1 Adaptin N terminal region NUC173 PF08161.12 KFQ94782.1 - 0.012 15.2 0.2 2.5 7.7 0.0 4.1 4 1 0 4 4 4 0 NUC173 domain DRIM PF07539.12 KFQ94782.1 - 0.024 12.9 0.1 5.2 5.2 0.0 3.3 3 1 0 4 4 4 0 Down-regulated in metastasis DNA_pol_phi PF04931.13 KFQ94782.1 - 0.026 12.6 0.0 4.3 5.3 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase phi UNC45-central PF11701.8 KFQ94782.1 - 0.027 14.4 0.5 0.097 12.6 0.0 2.2 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central Polyketide_cyc PF03364.20 KFQ94783.1 - 1e-23 83.9 0.0 1.3e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KFQ94783.1 - 0.0028 18.0 0.0 0.0049 17.2 0.0 1.5 1 1 1 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Cpn60_TCP1 PF00118.24 KFQ94784.1 - 7.1e-87 292.1 16.8 2e-86 290.6 16.8 1.6 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn10 PF00166.21 KFQ94785.1 - 1.4e-29 101.9 0.1 1.6e-29 101.8 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Mob1_phocein PF03637.17 KFQ94786.1 - 9.9e-35 120.0 1.1 1.4e-34 119.6 0.8 1.3 1 1 0 1 1 1 1 Mob1/phocein family Raftlin PF15250.6 KFQ94787.1 - 2.3e-184 613.5 0.0 1.2e-183 611.2 0.0 1.8 1 1 0 1 1 1 1 Raftlin PI-PLC-X PF00388.19 KFQ94788.1 - 9.2e-53 177.7 0.1 2e-52 176.6 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFQ94788.1 - 6.2e-41 139.3 0.4 1.7e-40 138.0 0.1 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain PH_12 PF16457.5 KFQ94788.1 - 3.1e-19 69.8 0.0 9.7e-19 68.2 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain C2 PF00168.30 KFQ94788.1 - 5e-18 65.3 0.0 2.4e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 C2 domain EF-hand_like PF09279.11 KFQ94788.1 - 1e-14 54.7 0.0 2.9e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like PH_14 PF17787.1 KFQ94788.1 - 9.2e-08 32.0 0.1 3.5e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 PH domain EF-hand_7 PF13499.6 KFQ94788.1 - 0.0074 16.7 2.1 0.028 14.9 0.1 2.8 3 0 0 3 3 3 1 EF-hand domain pair Mcp5_PH PF12814.7 KFQ94788.1 - 0.018 15.1 0.0 0.043 13.9 0.0 1.7 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KFQ94788.1 - 0.095 13.2 0.2 0.32 11.5 0.0 2.1 2 0 0 2 2 2 0 PH domain CUT PF02376.15 KFQ94789.1 - 2.6e-48 162.1 4.7 1.7e-24 85.7 0.1 3.4 4 0 0 4 4 4 2 CUT domain CUTL PF16557.5 KFQ94789.1 - 1.6e-42 143.6 1.5 1.6e-42 143.6 1.5 3.2 4 0 0 4 4 4 1 CUT1-like DNA-binding domain of SATB ULD PF16534.5 KFQ94789.1 - 1.7e-36 124.5 0.0 4.5e-36 123.2 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-like oligomerisation domain of SATB Homeodomain PF00046.29 KFQ94789.1 - 1.7e-06 27.8 0.0 5.3e-06 26.2 0.0 2.0 1 0 0 1 1 1 1 Homeodomain DUF3818 PF12825.7 KFQ94789.1 - 0.34 9.9 3.1 1.7 7.6 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) UPF0565 PF10561.9 KFQ94790.1 - 5.1e-97 324.7 0.5 5.9e-97 324.5 0.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0565 Cupin_8 PF13621.6 KFQ94791.1 - 6.7e-39 134.1 0.0 8.5e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KFQ94791.1 - 3.7e-10 39.8 0.0 5e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 KFQ94791.1 - 0.0075 16.7 0.0 0.014 15.9 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase FAD_binding_1 PF00667.20 KFQ94791.1 - 0.07 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain MBA1 PF07961.11 KFQ94792.1 - 0.096 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 MBA1-like protein DUF1387 PF07139.11 KFQ94793.1 - 5.5e-135 450.1 22.1 5.5e-135 450.1 22.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1387) DUF1296 PF06972.11 KFQ94793.1 - 0.089 12.9 0.5 0.089 12.9 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1296) Ig_4 PF16680.5 KFQ94793.1 - 1.7 9.0 5.1 2.1 8.7 1.4 2.9 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain BTB_2 PF02214.22 KFQ94794.1 - 6.7e-12 45.6 0.0 3.5e-11 43.3 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 KFQ94794.1 - 0.012 15.8 0.0 0.027 14.6 0.0 1.6 1 1 0 1 1 1 0 BTB/POZ domain Ashwin PF15323.6 KFQ94794.1 - 0.046 13.7 2.2 0.065 13.3 2.2 1.2 1 0 0 1 1 1 0 Developmental protein Shugoshin_C PF07557.11 KFQ94795.1 - 1.5e-09 37.5 0.4 2.8e-09 36.6 0.4 1.4 1 0 0 1 1 1 1 Shugoshin C terminus Ald_Xan_dh_C2 PF02738.18 KFQ94796.1 - 1.4e-194 647.7 0.0 1.7e-194 647.3 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KFQ94796.1 - 2.5e-41 141.3 0.0 5.6e-41 140.1 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 KFQ94796.1 - 1.3e-33 115.6 2.4 3e-33 114.5 2.4 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 KFQ94796.1 - 1.2e-30 105.3 1.1 3.2e-30 104.0 1.1 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 KFQ94796.1 - 3.4e-27 94.6 0.1 8.8e-26 90.1 0.0 3.0 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 KFQ94796.1 - 0.0002 21.3 1.9 0.0002 21.3 1.9 2.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain W2 PF02020.18 KFQ94798.1 - 2.8e-22 78.6 8.0 1.6e-20 73.0 3.7 3.0 3 0 0 3 3 3 2 eIF4-gamma/eIF5/eIF2-epsilon Pkinase PF00069.25 KFQ94799.1 - 3.2e-53 180.8 0.2 4.5e-53 180.3 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ94799.1 - 2.5e-25 89.2 0.4 3.1e-24 85.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pro_isomerase PF00160.21 KFQ94800.1 - 4.7e-53 179.7 0.0 5.3e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NIF3 PF01784.18 KFQ94801.1 - 2.4e-80 269.7 0.0 3.7e-80 269.1 0.0 1.2 1 1 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Hyccin PF09790.9 KFQ94802.1 - 5.8e-111 370.7 0.0 8e-111 370.2 0.0 1.2 1 0 0 1 1 1 1 Hyccin NDUF_B12 PF08122.12 KFQ94803.1 - 1.9e-23 82.2 0.8 3.1e-23 81.6 0.8 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Peptidase_C14 PF00656.22 KFQ94804.1 - 5.9e-46 157.4 0.0 8.8e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 Caspase domain DED PF01335.21 KFQ94804.1 - 3.1e-41 139.5 16.0 4.7e-21 74.9 6.7 2.5 2 0 0 2 2 2 2 Death effector domain FluMu_N PF17891.1 KFQ94804.1 - 0.16 11.8 0.0 10 6.0 0.0 2.7 2 0 0 2 2 2 0 Mu-like prophage FluMu N-terminal domain DED PF01335.21 KFQ94805.1 - 5e-43 145.3 12.4 1.7e-21 76.3 1.9 2.7 3 0 0 3 3 3 2 Death effector domain Peptidase_C14 PF00656.22 KFQ94805.1 - 1.4e-37 130.0 0.1 2.3e-37 129.3 0.1 1.4 1 0 0 1 1 1 1 Caspase domain PYRIN PF02758.16 KFQ94805.1 - 0.017 15.3 0.3 0.017 15.3 0.3 3.3 3 1 0 3 3 3 0 PAAD/DAPIN/Pyrin domain HAP1_N PF04849.13 KFQ94806.1 - 3.9e-126 420.4 36.2 6e-126 419.8 36.2 1.3 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Milton PF12448.8 KFQ94806.1 - 3.2e-34 118.6 1.7 3.2e-34 118.6 1.7 1.9 2 0 0 2 2 2 1 Kinesin associated protein DUF2937 PF11157.8 KFQ94806.1 - 0.12 12.1 1.0 0.47 10.1 1.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Mce4_CUP1 PF11887.8 KFQ94806.1 - 0.14 11.6 0.9 2.8 7.3 0.1 2.3 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Flu_NS2 PF00601.19 KFQ94806.1 - 1.6 9.0 8.9 9.2 6.6 0.2 3.4 2 1 1 3 3 3 0 Influenza non-structural protein (NS2) CCDC144C PF14915.6 KFQ94806.1 - 3.8 6.5 38.1 6.1 5.9 23.7 2.3 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region Pkinase PF00069.25 KFQ94807.1 - 9.6e-38 130.0 0.0 1.6e-36 126.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ94807.1 - 8e-29 100.7 0.0 7.2e-26 91.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ94807.1 - 0.077 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like ASXH PF13919.6 KFQ94807.1 - 0.15 12.1 0.1 0.27 11.3 0.1 1.3 1 0 0 1 1 1 0 Asx homology domain TMEM237 PF15383.6 KFQ94808.1 - 2.2e-105 351.2 0.4 3.1e-105 350.8 0.4 1.2 1 0 0 1 1 1 1 Transmembrane protein 237 CAF20 PF17052.5 KFQ94808.1 - 0.49 10.5 4.2 0.82 9.8 4.2 1.3 1 0 0 1 1 1 0 Cap associated factor RCC1 PF00415.18 KFQ94809.1 - 1.1e-40 138.0 14.9 3.3e-11 43.6 0.2 7.2 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFQ94809.1 - 5.1e-26 89.9 26.2 9.2e-07 28.5 1.3 7.3 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat MORN PF02493.20 KFQ94809.1 - 8.8e-26 88.2 29.8 2.6e-05 23.8 2.7 9.3 8 1 0 8 8 8 7 MORN repeat VPS9 PF02204.18 KFQ94809.1 - 5.6e-24 84.4 0.1 6.7e-23 80.9 0.2 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain RhoGEF PF00621.20 KFQ94809.1 - 1.3e-06 28.8 1.4 2.8e-06 27.7 1.4 1.6 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 KFQ94809.1 - 0.0037 17.7 0.0 0.012 16.1 0.0 1.9 1 0 0 1 1 1 1 PH domain Frizzled PF01534.17 KFQ94810.1 - 6e-139 462.6 20.2 7.3e-139 462.3 20.2 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 KFQ94810.1 - 7.7e-33 113.4 3.3 7.7e-33 113.4 3.3 1.7 2 0 0 2 2 2 1 Fz domain Rad60-SLD PF11976.8 KFQ94811.1 - 7.1e-22 77.0 0.2 8.5e-22 76.8 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KFQ94811.1 - 2e-18 65.9 0.7 2.4e-18 65.7 0.7 1.1 1 0 0 1 1 1 1 Ubiquitin family Nop PF01798.18 KFQ94812.1 - 1.9e-84 282.7 0.1 1.9e-84 282.7 0.1 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KFQ94812.1 - 7.9e-14 51.8 1.6 7.9e-14 51.8 1.6 2.7 3 0 0 3 3 3 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.11 KFQ94812.1 - 0.016 15.3 23.9 0.028 14.5 23.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 tRNA-synt_His PF13393.6 KFQ94812.1 - 0.22 10.8 2.0 2.7 7.2 1.8 2.4 2 0 0 2 2 2 0 Histidyl-tRNA synthetase Pkinase PF00069.25 KFQ94813.1 - 8e-33 113.9 0.0 1.5e-32 113.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ94813.1 - 2.5e-29 102.4 0.0 5.5e-29 101.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Activin_recp PF01064.23 KFQ94813.1 - 1.3e-11 45.5 7.3 1.3e-11 45.5 7.3 2.1 2 0 0 2 2 2 1 Activin types I and II receptor domain APH PF01636.23 KFQ94813.1 - 0.0015 18.5 0.0 0.0037 17.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KFQ94813.1 - 0.042 13.5 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Cadherin_C_2 PF16492.5 KFQ94813.1 - 0.072 13.8 0.1 1.1 10.0 0.0 2.8 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal FAM117 PF15388.6 KFQ94814.1 - 2.3e-123 411.6 12.1 3e-123 411.2 12.1 1.1 1 0 0 1 1 1 1 Protein Family FAM117 WD40 PF00400.32 KFQ94815.1 - 3.8e-34 116.2 28.4 1.5e-05 25.7 1.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ94815.1 - 1.2e-05 25.5 6.0 0.0079 16.5 0.1 4.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 KFQ94815.1 - 0.00061 20.3 0.0 0.0011 19.5 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 KFQ94815.1 - 0.21 10.2 8.3 1.5 7.4 0.3 3.1 1 1 1 3 3 3 0 Nucleoporin Nup120/160 ALS2CR8 PF15299.6 KFQ94816.1 - 1.2e-59 201.9 1.3 1.8e-59 201.3 1.3 1.2 1 0 0 1 1 1 1 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 zf-RING_9 PF13901.6 KFQ94817.1 - 4.5e-68 229.3 9.1 7.4e-68 228.6 8.3 1.8 2 0 0 2 2 2 1 Putative zinc-RING and/or ribbon PH PF00169.29 KFQ94817.1 - 8.2e-13 48.8 0.4 4e-09 36.9 0.0 3.0 3 0 0 3 3 3 2 PH domain PH_13 PF16652.5 KFQ94817.1 - 0.027 14.3 0.2 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain MAAL_N PF05034.13 KFQ94817.1 - 0.095 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase N-terminus Frizzled PF01534.17 KFQ94819.1 - 1.8e-140 467.6 13.1 2.2e-140 467.3 13.1 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 KFQ94819.1 - 3.7e-22 79.0 1.8 9.6e-22 77.7 1.8 1.7 1 0 0 1 1 1 1 Fz domain Cyclin_N PF00134.23 KFQ94820.1 - 8.1e-16 57.9 0.2 1.4e-15 57.1 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KFQ94820.1 - 8.9e-11 42.4 0.2 1.2e-10 42.0 0.2 1.4 1 0 0 1 1 1 1 Cyclin Methyltransf_16 PF10294.9 KFQ94821.1 - 2.8e-43 147.7 0.0 3.2e-43 147.5 0.0 1.0 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KFQ94821.1 - 9.3e-05 22.3 0.0 0.00012 21.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFQ94821.1 - 0.00025 20.6 0.0 0.0003 20.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KFQ94821.1 - 0.00031 20.3 0.0 0.00043 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KFQ94821.1 - 0.014 16.1 0.0 0.024 15.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MOR2-PAG1_mid PF14228.6 KFQ94821.1 - 0.049 11.3 0.0 0.06 11.0 0.0 1.0 1 0 0 1 1 1 0 Cell morphogenesis central region pKID PF02173.17 KFQ94822.1 - 1.3e-21 75.8 2.5 3.2e-21 74.5 2.5 1.7 1 0 0 1 1 1 1 pKID domain bZIP_1 PF00170.21 KFQ94822.1 - 1.9e-13 50.3 7.6 4.1e-13 49.2 7.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFQ94822.1 - 0.00061 19.8 3.0 0.00061 19.8 3.0 1.8 2 0 0 2 2 2 1 Basic region leucine zipper DUF4988 PF16378.5 KFQ94822.1 - 0.058 13.1 0.8 1.6 8.3 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function Rh5 PF18515.1 KFQ94822.1 - 0.067 12.5 2.0 0.097 12.0 2.0 1.2 1 0 0 1 1 1 0 Rh5 coiled-coil domain Nnf1 PF03980.14 KFQ94822.1 - 0.086 13.2 1.4 0.26 11.7 1.4 1.9 1 0 0 1 1 1 0 Nnf1 HNF-1A_C PF04813.12 KFQ94822.1 - 0.14 12.9 9.4 0.79 10.5 0.2 2.6 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus zf-H2C2_2 PF13465.6 KFQ94823.1 - 2.7e-09 37.0 10.9 1.7e-05 25.0 0.7 3.9 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ94823.1 - 6.6e-07 29.5 26.5 0.00013 22.3 0.5 4.0 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ94823.1 - 0.0079 17.0 19.7 0.057 14.3 0.7 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger FOXP-CC PF16159.5 KFQ94823.1 - 0.035 14.7 3.6 1.4 9.6 0.4 2.7 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KFQ94823.1 - 0.45 10.9 5.9 0.17 12.2 2.6 2.1 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 KFQ94823.1 - 5.9 6.7 23.7 0.3 10.9 2.1 4.4 4 1 0 4 4 4 0 C2H2-type zinc-finger domain Peptidase_M14 PF00246.24 KFQ94824.1 - 2.5e-88 296.6 0.2 3e-88 296.4 0.2 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KFQ94824.1 - 5.2e-15 55.6 0.9 1.4e-14 54.2 0.9 1.8 1 0 0 1 1 1 1 Carboxypeptidase activation peptide DUF1642 PF07852.11 KFQ94824.1 - 0.0022 18.6 0.2 0.0048 17.5 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1642) FAST_1 PF06743.15 KFQ94825.1 - 2.5e-22 78.6 11.4 5.5e-22 77.5 0.3 5.2 4 2 2 6 6 6 1 FAST kinase-like protein, subdomain 1 FAST_2 PF08368.12 KFQ94825.1 - 5.2e-09 36.8 0.0 2.2e-08 34.7 0.0 2.2 1 0 0 1 1 1 1 FAST kinase-like protein, subdomain 2 RAP PF08373.10 KFQ94825.1 - 1.6e-07 31.3 0.0 4.1e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 RAP domain Ldh_1_C PF02866.18 KFQ94826.1 - 4.4e-08 33.2 0.0 1.7e-06 28.1 0.0 2.4 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain MRP-S24 PF14955.6 KFQ94826.1 - 0.013 15.5 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S24 Ldh_1_N PF00056.23 KFQ94826.1 - 0.15 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain EF-hand_3 PF09069.11 KFQ94827.1 - 6.5e-19 68.1 0.0 1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 EF-hand EF-hand_2 PF09068.11 KFQ94827.1 - 0.00075 19.6 0.0 0.0013 18.9 0.0 1.4 1 0 0 1 1 1 1 EF hand Aminotran_4 PF01063.19 KFQ94828.1 - 0.0041 17.0 0.0 0.0049 16.8 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Ycf4 PF02392.16 KFQ94829.1 - 0.065 12.8 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 Ycf4 DUF1440 PF07274.12 KFQ94829.1 - 0.1 13.0 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1440) 7tm_1 PF00001.21 KFQ94830.1 - 2.9e-43 148.1 21.7 4e-43 147.6 21.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFQ94830.1 - 0.00019 20.8 4.2 0.00019 20.8 4.2 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw EF1_GNE PF00736.19 KFQ94831.1 - 1.8e-37 127.4 0.3 3.4e-37 126.5 0.3 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KFQ94831.1 - 1.5e-13 50.9 9.7 6.7e-13 48.8 9.7 2.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region Tnp_22_trimer PF17489.2 KFQ94831.1 - 0.041 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 L1 transposable element trimerization domain YL1 PF05764.13 KFQ94831.1 - 0.077 13.1 4.1 0.094 12.8 4.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Molybdopterin PF00384.22 KFQ94832.1 - 8.3e-75 252.4 0.0 1e-73 248.8 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KFQ94832.1 - 6.9e-18 64.5 1.3 9.4e-18 64.1 0.1 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 KFQ94832.1 - 1.3e-17 64.1 0.0 3.1e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 KFQ94832.1 - 3e-17 61.9 0.1 7.8e-17 60.5 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 KFQ94832.1 - 1.3e-09 37.9 0.4 1.3e-09 37.9 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 KFQ94832.1 - 0.05 13.4 1.0 9.8 5.9 0.1 2.8 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 KFQ94832.1 - 0.4 10.6 2.4 16 5.5 0.4 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain zf-C3Hc3H PF13891.6 KFQ94833.1 - 1.6e-17 63.6 5.8 1.6e-17 63.6 5.8 2.3 3 0 0 3 3 3 1 Potential DNA-binding domain CUB PF00431.20 KFQ94834.1 - 1.9e-59 198.8 0.0 1.2e-29 102.9 0.0 2.5 2 0 0 2 2 2 2 CUB domain F5_F8_type_C PF00754.25 KFQ94834.1 - 5.5e-50 168.7 1.9 2.9e-26 92.1 1.3 2.4 2 0 0 2 2 2 2 F5/8 type C domain DUF3481 PF11980.8 KFQ94834.1 - 2.1e-42 142.7 0.5 4.3e-42 141.7 0.5 1.6 1 0 0 1 1 1 1 C-terminal domain of neuropilin glycoprotein MAM PF00629.23 KFQ94834.1 - 3e-25 89.0 0.0 7.7e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu DUF1804 PF08822.11 KFQ94834.1 - 0.25 11.3 0.0 20 5.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) RNA_polI_A34 PF08208.11 KFQ94837.1 - 0.0063 16.6 20.2 0.0065 16.6 20.2 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 SR-25 PF10500.9 KFQ94837.1 - 0.02 14.5 13.2 0.028 14.0 13.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein YL1 PF05764.13 KFQ94837.1 - 0.03 14.5 16.7 0.032 14.3 16.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein TFIIF_alpha PF05793.12 KFQ94837.1 - 0.48 8.9 23.1 0.62 8.6 23.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RR_TM4-6 PF06459.12 KFQ94837.1 - 1.1 9.1 13.5 1.4 8.7 13.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SRP-alpha_N PF04086.13 KFQ94837.1 - 1.1 9.1 16.6 1.2 9.0 16.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal eIF3_subunit PF08597.10 KFQ94837.1 - 1.7 8.5 21.5 2.3 8.1 21.5 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Presenilin PF01080.17 KFQ94837.1 - 2.9 6.6 7.6 3.4 6.4 7.6 1.1 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 KFQ94837.1 - 5.8 6.6 6.9 6.5 6.4 6.9 1.2 1 0 0 1 1 1 0 Connexin Coilin_N PF15862.5 KFQ94837.1 - 6.6 6.5 16.3 8.5 6.2 16.3 1.4 1 1 0 1 1 1 0 Coilin N-terminus Hid1 PF12722.7 KFQ94837.1 - 8 4.4 7.8 9.3 4.2 7.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PDZ PF00595.24 KFQ94838.1 - 6.5e-23 80.9 0.2 1.5e-18 66.9 0.1 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFQ94838.1 - 5e-14 51.9 0.1 4.3e-10 39.3 0.1 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFQ94838.1 - 3.4e-10 40.1 0.0 1.8e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 PDZ domain V-set_2 PF15910.5 KFQ94840.1 - 9.1e-38 128.8 1.6 1.5e-37 128.2 1.6 1.3 1 0 0 1 1 1 1 ICOS V-set domain TMEM154 PF15102.6 KFQ94840.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Insulin_TMD PF17870.1 KFQ94840.1 - 0.053 13.6 0.0 0.095 12.8 0.0 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment NCU-G1 PF15065.6 KFQ94840.1 - 0.08 11.9 0.2 0.13 11.2 0.2 1.2 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 FAM176 PF14851.6 KFQ94840.1 - 0.1 12.3 0.2 0.18 11.5 0.2 1.4 1 0 0 1 1 1 0 FAM176 family V-set PF07686.17 KFQ94841.1 - 7.2e-13 48.7 0.0 9.6e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain V-set_2 PF15910.5 KFQ94841.1 - 1.5e-11 44.3 0.1 2e-11 44.0 0.1 1.2 1 0 0 1 1 1 1 ICOS V-set domain Ig_3 PF13927.6 KFQ94841.1 - 0.01 16.4 0.0 0.02 15.5 0.0 1.5 1 1 0 1 1 1 0 Immunoglobulin domain Ig_6 PF18452.1 KFQ94841.1 - 0.03 13.9 0.0 0.074 12.6 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFQ94841.1 - 0.13 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain V-set_2 PF15910.5 KFQ94842.1 - 8.3e-11 42.0 0.3 1.4e-10 41.3 0.3 1.3 1 0 0 1 1 1 1 ICOS V-set domain V-set PF07686.17 KFQ94842.1 - 2.3e-06 27.7 0.4 4.2e-06 26.9 0.4 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain DUF1195 PF06708.11 KFQ94842.1 - 0.033 13.9 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1195) RA PF00788.23 KFQ94843.1 - 1.7e-13 51.0 2.8 4.1e-13 49.8 0.3 2.6 2 1 1 3 3 3 1 Ras association (RalGDS/AF-6) domain PH PF00169.29 KFQ94843.1 - 4.6e-11 43.2 0.2 1e-10 42.0 0.2 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFQ94843.1 - 0.0031 17.9 0.7 0.0031 17.9 0.7 2.8 2 2 0 2 2 2 1 Pleckstrin homology domain RBD PF02196.15 KFQ94843.1 - 0.0052 16.8 0.1 0.024 14.7 0.0 2.2 2 0 0 2 2 2 1 Raf-like Ras-binding domain FERM_N PF09379.10 KFQ94843.1 - 0.02 14.8 0.2 0.048 13.6 0.2 1.7 1 0 0 1 1 1 0 FERM N-terminal domain Abi_HHR PF07815.14 KFQ94844.1 - 4e-35 119.8 0.2 7.1e-35 119.0 0.2 1.4 1 0 0 1 1 1 1 Abl-interactor HHR SH3_1 PF00018.28 KFQ94844.1 - 5.7e-09 35.4 0.7 9.5e-09 34.7 0.7 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFQ94844.1 - 1.2e-06 28.2 0.1 2.1e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFQ94844.1 - 0.0019 17.8 0.1 0.0037 16.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain ATP-synt_ab_Xtn PF16886.5 KFQ94844.1 - 0.15 11.9 0.0 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 ATPsynthase alpha/beta subunit N-term extension p450 PF00067.22 KFQ94845.1 - 7.3e-46 156.9 0.2 9.2e-46 156.5 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S51 PF03575.17 KFQ94846.1 - 1.5e-43 148.8 0.0 1.7e-43 148.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family S51 ID PF18543.1 KFQ94846.1 - 0.033 14.2 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Intracellular delivery domain Beach PF02138.18 KFQ94848.1 - 6.7e-123 409.4 0.3 7.5e-123 409.3 0.3 1.0 1 0 0 1 1 1 1 Beige/BEACH domain Shugoshin_C PF07557.11 KFQ94851.1 - 0.012 15.4 1.0 0.022 14.5 1.0 1.4 1 0 0 1 1 1 0 Shugoshin C terminus Iso_dh PF00180.20 KFQ94852.1 - 8.4e-79 265.2 0.0 1e-78 265.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF3364 PF11844.8 KFQ94852.1 - 0.13 12.5 0.4 3.8 7.8 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3364) PIP5K PF01504.18 KFQ94853.1 - 1.3e-43 149.2 0.7 5.8e-34 117.6 0.5 2.5 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KFQ94853.1 - 2.4e-32 112.2 0.3 4e-32 111.5 0.3 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KFQ94853.1 - 9.4e-16 57.7 14.0 9.4e-16 57.7 14.0 2.3 2 0 0 2 2 2 1 FYVE zinc finger DEP PF00610.21 KFQ94853.1 - 1.7e-05 24.8 0.0 4.7e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Thioredoxin PF00085.20 KFQ94854.1 - 2.6e-89 294.0 0.5 2.3e-24 85.4 0.1 6.0 6 0 0 6 6 6 4 Thioredoxin DnaJ PF00226.31 KFQ94854.1 - 2.8e-24 85.0 2.8 6.2e-24 83.9 2.8 1.6 1 0 0 1 1 1 1 DnaJ domain Thioredoxin_2 PF13098.6 KFQ94854.1 - 5.5e-15 55.8 2.1 0.00015 22.1 0.0 5.8 4 2 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFQ94854.1 - 6.3e-13 48.9 1.7 0.075 13.4 0.0 6.1 4 2 2 6 6 6 3 Thioredoxin-like Thioredoxin_6 PF13848.6 KFQ94854.1 - 6.4e-12 45.7 0.0 0.0019 18.2 0.0 3.9 2 2 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFQ94854.1 - 1.1e-09 38.3 1.6 0.4 10.9 0.0 4.8 4 0 0 4 4 4 3 Thioredoxin-like OST3_OST6 PF04756.13 KFQ94854.1 - 3.2e-09 36.6 0.0 0.023 14.1 0.0 4.2 3 1 1 4 4 4 3 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KFQ94854.1 - 4.1e-08 33.2 1.8 0.48 10.4 0.1 4.7 4 0 0 4 4 4 2 AhpC/TSA family Redoxin PF08534.10 KFQ94854.1 - 9.1e-08 31.9 1.9 0.082 12.6 0.0 3.8 4 0 0 4 4 4 2 Redoxin Thioredoxin_9 PF14595.6 KFQ94854.1 - 3.1e-06 27.0 2.1 0.44 10.3 0.1 3.8 2 1 0 3 3 3 2 Thioredoxin TraF PF13728.6 KFQ94854.1 - 0.00012 22.0 1.3 0.14 12.0 0.0 3.6 4 0 0 4 4 4 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 KFQ94854.1 - 0.0068 16.4 0.0 2.3 8.3 0.0 2.9 2 0 0 2 2 2 1 Thioredoxin domain Calsequestrin PF01216.17 KFQ94854.1 - 0.044 12.8 0.0 2.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Calsequestrin RMMBL PF07521.12 KFQ94854.1 - 0.054 13.4 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain PDEase_I PF00233.19 KFQ94855.1 - 1.8e-81 273.4 8.7 2.6e-81 272.9 8.2 1.5 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.12 KFQ94855.1 - 4.6e-31 106.4 0.1 1.1e-30 105.2 0.1 1.7 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal DARPP-32 PF05395.12 KFQ94856.1 - 7.6e-32 110.7 6.4 9.9e-32 110.4 6.4 1.1 1 0 0 1 1 1 1 Protein phosphatase inhibitor 1/DARPP-32 SSFA2_C PF14723.6 KFQ94857.1 - 1.6e-73 246.4 10.8 1.6e-73 246.4 10.8 2.5 2 0 0 2 2 2 1 Sperm-specific antigen 2 C-terminus KRAP_IP3R_bind PF14722.6 KFQ94857.1 - 1.3e-56 190.4 0.3 5.3e-56 188.4 0.3 2.1 1 0 0 1 1 1 1 Ki-ras-induced actin-interacting protein-IP3R-interacting domain PBP1_TM PF14812.6 KFQ94857.1 - 1.2 9.6 7.9 4.3 7.8 7.9 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DAGK_cat PF00781.24 KFQ94858.1 - 1.3e-22 79.8 0.0 5e-22 77.9 0.0 2.0 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain Integrin_alpha2 PF08441.12 KFQ94859.1 - 9.1e-77 258.9 5.6 1.7e-74 251.4 2.9 2.3 1 1 1 2 2 2 2 Integrin alpha FG-GAP PF01839.23 KFQ94859.1 - 1.9e-19 69.5 18.3 2.3e-09 37.2 0.0 4.5 5 0 0 5 5 5 3 FG-GAP repeat VCBS PF13517.6 KFQ94859.1 - 2.3e-11 44.1 5.9 1e-07 32.4 0.1 3.0 2 1 1 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.20 KFQ94859.1 - 0.00075 19.3 0.5 0.0016 18.2 0.5 1.6 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region AlgF PF11182.8 KFQ94859.1 - 0.069 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Alginate O-acetyl transferase AlgF UQ_con PF00179.26 KFQ94860.1 - 8.2e-47 158.4 0.0 1.1e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFQ94860.1 - 0.009 15.7 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KFQ94860.1 - 0.0094 16.2 0.1 0.015 15.6 0.1 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KFQ94860.1 - 0.16 11.8 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 UEV domain DUF4663 PF15668.5 KFQ94860.1 - 2.4 7.1 5.2 3.4 6.6 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) MA3 PF02847.17 KFQ94861.1 - 1.5e-24 86.2 1.7 3.2e-24 85.1 1.7 1.6 1 0 0 1 1 1 1 MA3 domain Phage_Gp17 PF17549.2 KFQ94861.1 - 0.035 14.1 1.3 0.086 12.9 1.3 1.6 1 0 0 1 1 1 0 Gene Product 17 SSP160 PF06933.11 KFQ94861.1 - 0.039 12.2 7.8 0.064 11.5 7.8 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-met PF12874.7 KFQ94862.1 - 9.4e-29 98.9 25.2 1.2e-07 31.8 1.9 4.4 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFQ94862.1 - 2.3e-22 78.7 20.7 3e-06 27.3 3.0 4.3 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFQ94862.1 - 9.7e-10 38.7 9.7 0.15 12.4 0.4 4.2 4 0 0 4 4 4 4 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.12 KFQ94862.1 - 2.2e-09 36.9 12.2 0.016 15.0 0.0 4.3 4 0 0 4 4 4 4 U1 zinc finger AKAP95 PF04988.12 KFQ94862.1 - 1.5e-06 28.5 6.1 0.19 11.9 0.1 4.2 4 0 0 4 4 4 2 A-kinase anchoring protein 95 (AKAP95) zf-DBF PF07535.12 KFQ94862.1 - 0.0083 16.2 13.3 0.19 11.8 0.8 4.3 4 0 0 4 4 4 1 DBF zinc finger DUF3449 PF11931.8 KFQ94862.1 - 0.01 15.6 1.0 8.7 6.1 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) zf-C2H2 PF00096.26 KFQ94862.1 - 0.017 15.5 12.4 5.2 7.7 1.4 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type UPF0728 PF15092.6 KFQ94862.1 - 0.094 12.6 0.1 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0728 zf-C2H2_9 PF16293.5 KFQ94862.1 - 0.25 11.2 8.4 29 4.6 0.3 4.2 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_15 PF17032.5 KFQ94862.1 - 0.27 12.0 7.7 5.8 7.8 0.2 3.6 3 1 0 3 3 3 0 zinc-ribbon family zf-C2H2_4 PF13894.6 KFQ94862.1 - 0.27 12.2 9.9 11 7.2 0.4 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-piccolo PF05715.13 KFQ94862.1 - 0.43 10.8 6.7 21 5.3 0.1 4.1 4 0 0 4 4 4 0 Piccolo Zn-finger zf-RING_7 PF02591.15 KFQ94862.1 - 0.68 10.2 3.4 8.4 6.7 0.1 3.8 4 0 0 4 4 4 0 C4-type zinc ribbon domain C1_1 PF00130.22 KFQ94862.1 - 0.94 9.4 4.2 21 5.1 0.0 3.7 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Actin_micro PF17003.5 KFQ94862.1 - 1.2 8.3 13.5 1.9 7.6 0.1 3.6 3 1 0 3 3 3 0 Putative actin-like family IBR PF01485.21 KFQ94862.1 - 1.6 9.0 5.9 8.5 6.7 0.0 3.4 3 1 0 3 3 3 0 IBR domain, a half RING-finger domain zf_C2H2_ZHX PF18387.1 KFQ94862.1 - 2.1 8.1 9.9 1.3 8.7 0.4 2.9 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain CRAL_TRIO_2 PF13716.6 KFQ94863.1 - 1.1e-07 32.1 0.1 2.2e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Spectrin PF00435.21 KFQ94863.1 - 0.00013 22.4 24.5 0.0012 19.3 0.4 4.8 4 1 1 5 5 5 2 Spectrin repeat MatP PF06303.12 KFQ94863.1 - 0.061 13.9 3.1 1 10.0 0.9 3.0 2 0 0 2 2 2 0 MatP N-terminal domain Spectrin PF00435.21 KFQ94864.1 - 0.17 12.4 17.8 0.24 11.9 2.4 3.1 2 1 0 2 2 2 0 Spectrin repeat DUF948 PF06103.11 KFQ94864.1 - 0.44 10.8 2.4 30 5.0 0.1 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Spectrin PF00435.21 KFQ94865.1 - 0.034 14.6 6.8 1 9.9 2.6 2.2 2 0 0 2 2 2 0 Spectrin repeat Coagulase PF08764.10 KFQ94865.1 - 0.043 14.0 0.9 0.053 13.7 0.9 1.0 1 0 0 1 1 1 0 Staphylococcus aureus coagulase I-set PF07679.16 KFQ94866.1 - 5.9e-05 23.1 1.1 0.00015 21.8 0.1 2.3 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ94866.1 - 0.0012 19.4 0.8 0.0033 18.0 0.1 2.1 2 0 0 2 2 2 1 Immunoglobulin domain 7tm_6 PF02949.20 KFQ94866.1 - 0.002 17.3 4.7 0.032 13.3 0.2 2.9 3 0 0 3 3 3 2 7tm Odorant receptor MCPsignal PF00015.21 KFQ94866.1 - 0.009 15.8 1.0 5.7 6.7 0.0 3.3 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DHHA1 PF02272.19 KFQ94866.1 - 0.19 12.2 9.3 0.03 14.7 4.6 2.1 2 0 0 2 2 2 0 DHHA1 domain LPD29 PF18847.1 KFQ94866.1 - 0.25 12.3 1.8 1.7 9.6 1.8 2.6 1 1 0 1 1 1 0 Large polyvalent protein associated domain 29 GARP PF16731.5 KFQ94866.1 - 0.55 9.9 4.2 12 5.6 0.9 3.3 1 1 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma CorA PF01544.18 KFQ94866.1 - 1 8.6 13.5 0.061 12.6 1.1 3.5 1 1 1 3 3 3 0 CorA-like Mg2+ transporter protein DASH_Dad2 PF08654.10 KFQ94866.1 - 1.8 9.0 9.0 1.8 9.0 0.0 4.6 3 1 0 3 3 3 0 DASH complex subunit Dad2 Retrotrans_gag PF03732.17 KFQ94866.1 - 2.6 8.4 12.6 0.75 10.1 4.1 4.1 4 1 0 4 4 4 0 Retrotransposon gag protein Latarcin PF10279.9 KFQ94866.1 - 7.4 7.1 9.6 1.1 9.8 2.5 3.3 2 1 1 3 3 3 0 Latarcin precursor CLZ PF16526.5 KFQ94866.1 - 8.6 6.8 15.5 12 6.4 1.0 5.0 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels I-set PF07679.16 KFQ94867.1 - 0 1842.8 51.8 6.4e-23 80.6 0.0 35.2 35 0 0 35 35 35 35 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ94867.1 - 0 1097.2 17.0 1.4e-15 57.6 0.0 35.4 35 0 0 35 35 35 34 Immunoglobulin domain ig PF00047.25 KFQ94867.1 - 2.9e-194 629.9 48.7 3.9e-12 46.2 0.1 33.1 34 0 0 34 34 33 29 Immunoglobulin domain Ig_2 PF13895.6 KFQ94867.1 - 1.8e-190 617.8 36.0 2.7e-12 46.9 0.1 32.6 29 2 3 32 32 32 25 Immunoglobulin domain V-set PF07686.17 KFQ94867.1 - 3.3e-67 223.5 63.0 0.0018 18.5 0.2 42.0 32 15 0 32 32 32 14 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFQ94867.1 - 1.8e-46 156.1 4.7 0.013 15.5 0.0 22.5 25 0 0 25 25 24 9 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFQ94867.1 - 3.7e-30 104.2 27.0 0.00014 22.2 0.0 22.7 27 0 0 27 27 25 5 Immunoglobulin C1-set domain Receptor_2B4 PF11465.8 KFQ94867.1 - 4.1e-26 91.3 22.7 0.039 14.2 0.1 18.9 20 2 2 22 22 21 5 Natural killer cell receptor 2B4 Titin_Z PF09042.11 KFQ94867.1 - 2e-19 69.2 19.5 1.8e-12 47.0 7.3 3.1 2 0 0 2 2 2 2 Titin Z Ig_6 PF18452.1 KFQ94867.1 - 8.7e-18 63.6 4.2 0.39 10.3 0.0 13.2 14 0 0 14 14 13 2 Immunoglobulin domain Ig_5 PF16681.5 KFQ94867.1 - 1.5e-16 60.5 39.1 0.098 13.1 0.1 17.9 21 0 0 21 21 19 5 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFQ94867.1 - 6.3e-14 52.0 32.3 0.15 12.3 0.1 17.2 21 0 0 21 21 19 4 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 KFQ94867.1 - 1.7e-12 47.2 10.3 0.015 15.3 0.1 12.3 14 0 0 14 14 13 1 C17orf99 Ig domain Izumo-Ig PF16706.5 KFQ94867.1 - 3e-11 43.2 23.8 0.72 10.0 0.0 15.9 20 0 0 20 20 16 3 Izumo-like Immunoglobulin domain V-set_CD47 PF08204.11 KFQ94867.1 - 6.3e-07 29.4 24.8 0.69 9.9 0.1 11.8 13 0 0 13 13 12 3 CD47 immunoglobulin-like domain PKD_3 PF16820.5 KFQ94867.1 - 0.0026 17.4 1.6 0.82 9.5 0.0 5.9 6 0 0 6 6 5 1 PKD-like domain DUF2158 PF09926.9 KFQ94867.1 - 0.0084 15.8 7.1 30 4.4 0.0 8.1 9 0 0 9 9 7 0 Uncharacterized small protein (DUF2158) DUF4198 PF10670.9 KFQ94867.1 - 0.017 15.5 9.1 0.14 12.5 0.0 7.2 9 0 0 9 9 6 0 Domain of unknown function (DUF4198) Laminin_G_1 PF00054.23 KFQ94867.1 - 0.071 13.3 0.1 5.8 7.2 0.0 4.0 4 0 0 4 4 3 0 Laminin G domain CRR7 PF12095.8 KFQ94867.1 - 0.21 12.0 1.1 1.8 9.0 0.0 3.1 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 PKD PF00801.20 KFQ94867.1 - 0.44 10.4 2.1 96 2.9 0.0 5.4 5 0 0 5 5 5 0 PKD domain I-set PF07679.16 KFQ94868.1 - 5.6e-12 45.6 0.0 7.4e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ94868.1 - 9.2e-07 29.4 0.0 1.5e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFQ94868.1 - 3.4e-05 23.9 0.0 4.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 KFQ94868.1 - 0.00023 20.7 0.0 0.00036 20.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFQ94868.1 - 0.00034 20.9 0.0 0.00059 20.1 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFQ94868.1 - 0.0011 18.9 0.0 0.0021 18.1 0.0 1.4 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain V-set PF07686.17 KFQ94868.1 - 0.0025 18.0 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain fn3 PF00041.21 KFQ94869.1 - 2.9e-104 341.6 7.1 5.4e-21 74.7 0.1 7.3 7 0 0 7 7 7 7 Fibronectin type III domain I-set PF07679.16 KFQ94869.1 - 1e-32 112.0 1.7 1.1e-14 54.2 0.1 4.1 4 0 0 4 4 4 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ94869.1 - 5e-19 68.7 0.0 1.8e-08 34.8 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFQ94869.1 - 5e-18 65.5 9.6 0.0025 18.3 0.1 7.9 8 0 0 8 8 8 5 Purple acid Phosphatase, N-terminal domain ig PF00047.25 KFQ94869.1 - 3.1e-11 43.3 0.0 0.00015 21.8 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFQ94869.1 - 7.6e-10 39.0 0.0 0.00048 20.4 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain Tissue_fac PF01108.17 KFQ94869.1 - 3.5e-09 36.5 0.1 0.0021 17.9 0.0 5.4 5 0 0 5 5 5 1 Tissue factor SusE PF14292.6 KFQ94869.1 - 5.4e-06 26.6 0.1 0.99 9.7 0.0 4.5 4 0 0 4 4 4 2 SusE outer membrane protein fn3_2 PF16893.5 KFQ94869.1 - 3.6e-05 23.8 0.0 2.9 8.1 0.0 5.4 7 0 0 7 7 6 1 Fibronectin type III domain PhoD_N PF16655.5 KFQ94869.1 - 0.0022 18.5 0.2 26 5.4 0.0 4.3 4 0 0 4 4 4 0 PhoD-like phosphatase, N-terminal domain Lipocalin_7 PF14651.6 KFQ94869.1 - 0.0024 17.8 0.0 1.4 8.9 0.0 3.6 4 1 0 4 4 4 1 Lipocalin / cytosolic fatty-acid binding protein family Reeler PF02014.16 KFQ94869.1 - 0.0092 16.7 0.1 50 4.6 0.0 4.5 5 0 0 5 5 5 0 Reeler domain Herpes_gE PF02480.16 KFQ94869.1 - 0.077 11.7 0.1 0.43 9.3 0.0 1.9 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E I-set PF07679.16 KFQ94870.1 - 9.2e-09 35.3 0.0 9.4e-09 35.2 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ94870.1 - 2.6e-05 24.7 0.0 2.7e-05 24.7 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFQ94870.1 - 0.027 14.8 0.0 0.03 14.7 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain C2-set_2 PF08205.12 KFQ94870.1 - 0.17 11.9 0.1 0.18 11.9 0.1 1.2 1 1 0 1 1 1 0 CD80-like C2-set immunoglobulin domain I-set PF07679.16 KFQ94871.1 - 7.9e-08 32.3 0.0 8.2e-08 32.2 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ94871.1 - 3.3e-06 27.6 0.0 3.4e-06 27.6 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFQ94871.1 - 0.0088 16.4 0.0 0.01 16.2 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 KFQ94871.1 - 0.049 13.7 0.0 0.049 13.7 0.0 1.1 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain DUF2550 PF10739.9 KFQ94871.1 - 0.15 12.1 0.0 0.15 12.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2550) I-set PF07679.16 KFQ94872.1 - 6e-07 29.4 0.0 6.5e-07 29.3 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ94872.1 - 2.4e-06 28.1 0.0 2.4e-06 28.0 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFQ94872.1 - 0.14 12.5 0.0 0.16 12.3 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFQ94873.1 - 5.3e-07 29.6 0.0 5.6e-07 29.5 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ94873.1 - 2.2e-05 24.9 0.0 2.3e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ94874.1 - 5.1e-07 29.7 0.0 5.3e-07 29.6 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ94874.1 - 2e-05 25.1 0.0 2e-05 25.1 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFQ94874.1 - 0.0016 18.5 0.0 0.0021 18.2 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ94875.1 - 4.7e-09 36.2 0.0 4.9e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ94875.1 - 1.6e-06 28.6 0.0 1.7e-06 28.5 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFQ94875.1 - 0.0031 17.7 0.0 0.0036 17.4 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFQ94875.1 - 0.0081 16.5 0.0 0.0085 16.4 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ94876.1 - 1.8e-10 40.7 0.0 1.9e-10 40.7 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ94876.1 - 1.1e-08 35.5 0.1 1.1e-08 35.5 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFQ94876.1 - 0.00026 21.1 0.1 0.00032 20.8 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFQ94876.1 - 0.0007 19.9 0.0 0.00073 19.8 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFQ94876.1 - 0.0031 17.6 0.0 0.0035 17.5 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFQ94877.1 - 7.5e-08 32.3 0.0 8.1e-08 32.2 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ94877.1 - 4.6e-07 30.3 0.0 5e-07 30.2 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFQ94877.1 - 0.013 15.9 0.0 0.014 15.8 0.0 1.0 1 0 0 1 1 1 0 Immunoglobulin domain DUF3922 PF13059.6 KFQ94877.1 - 0.039 14.4 0.1 0.041 14.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3992) ig PF00047.25 KFQ94877.1 - 0.063 13.5 0.0 0.09 13.0 0.0 1.2 1 1 0 1 1 1 0 Immunoglobulin domain C2-set_2 PF08205.12 KFQ94877.1 - 0.064 13.3 0.0 0.068 13.2 0.0 1.1 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain I-set PF07679.16 KFQ94878.1 - 2.9e-77 254.8 4.1 4.9e-26 90.6 0.0 5.3 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ94878.1 - 1.7e-54 182.4 2.6 1.8e-15 57.3 0.0 5.7 5 0 0 5 5 5 5 Immunoglobulin domain Ig_2 PF13895.6 KFQ94878.1 - 2.8e-32 110.9 2.3 2.9e-08 33.9 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 KFQ94878.1 - 3e-29 101.0 6.5 7.2e-12 45.3 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.17 KFQ94878.1 - 8.7e-22 77.4 11.0 5.6e-06 26.5 0.1 8.2 5 3 1 6 6 6 6 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFQ94878.1 - 1.4e-08 34.7 1.8 0.0016 18.5 0.0 5.3 6 0 0 6 6 6 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFQ94878.1 - 3.8e-07 30.4 1.0 0.015 15.7 0.0 5.2 5 0 0 5 5 5 1 Immunoglobulin C1-set domain Receptor_2B4 PF11465.8 KFQ94878.1 - 1.2e-06 28.7 2.2 1.8 8.8 0.0 4.3 4 0 0 4 4 4 3 Natural killer cell receptor 2B4 Ig_4 PF16680.5 KFQ94878.1 - 9e-05 22.7 1.7 1.1 9.6 0.1 4.3 4 1 0 4 4 3 1 T-cell surface glycoprotein CD3 delta chain PKD_3 PF16820.5 KFQ94878.1 - 0.00012 21.8 0.0 0.19 11.5 0.0 4.0 4 0 0 4 4 4 1 PKD-like domain Ig_5 PF16681.5 KFQ94878.1 - 0.00036 20.9 3.7 2.5 8.5 0.3 5.1 4 2 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain MetRS-N PF09635.10 KFQ94878.1 - 0.05 14.1 0.2 0.44 11.1 0.0 2.5 2 0 0 2 2 2 0 MetRS-N binding domain DarA_N PF18788.1 KFQ94878.1 - 0.061 13.4 1.5 0.097 12.8 0.3 1.9 2 0 0 2 2 1 0 Defence against restriction A N-terminal Egh16-like PF11327.8 KFQ94878.1 - 0.1 13.0 0.7 17 5.7 0.0 3.1 2 1 1 3 3 3 0 Egh16-like virulence factor FAD_binding_6 PF00970.24 KFQ94878.1 - 0.11 12.8 0.0 0.38 11.1 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain DUF4198 PF10670.9 KFQ94878.1 - 0.14 12.5 4.6 3.8 7.8 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4198) PH PF00169.29 KFQ94879.1 - 2.4e-10 40.8 0.0 5.3e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFQ94879.1 - 2.2e-05 24.8 0.5 0.00015 22.1 0.1 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 KFQ94879.1 - 3.9e-05 23.9 0.0 9.4e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain Muted PF14942.6 KFQ94879.1 - 0.015 15.6 0.5 0.032 14.6 0.5 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Cmc1 PF08583.10 KFQ94879.1 - 0.059 13.4 1.6 4.5 7.4 0.1 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like PH_6 PF15406.6 KFQ94879.1 - 0.1 12.9 0.0 0.39 11.0 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain DUF5327 PF17261.2 KFQ94879.1 - 0.26 12.1 0.2 0.26 12.1 0.2 2.0 2 1 0 2 2 2 0 Family of unknown function (DUF5327) FKBP_C PF00254.28 KFQ94880.1 - 1.2e-30 105.7 0.0 1.8e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_7 PF13499.6 KFQ94880.1 - 7.1e-08 32.8 1.2 1.2e-07 32.0 1.2 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFQ94880.1 - 1.2e-07 31.1 2.6 0.01 15.7 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KFQ94880.1 - 2.9e-07 29.5 2.1 0.0031 16.9 0.3 2.4 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KFQ94880.1 - 3.1e-06 26.4 1.0 0.0032 16.9 0.2 2.6 2 0 0 2 2 2 2 EF hand Gasdermin PF04598.12 KFQ94881.1 - 8e-17 61.5 0.0 9.2e-17 61.3 0.0 1.0 1 0 0 1 1 1 1 Gasdermin pore forming domain DUF4663 PF15668.5 KFQ94881.1 - 0.0057 15.8 0.0 0.0063 15.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4663) Oxysterol_BP PF01237.18 KFQ94882.1 - 3.7e-128 427.5 0.5 3.7e-128 427.5 0.5 2.2 2 1 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.6 KFQ94882.1 - 4.5e-13 49.3 0.4 1e-12 48.1 0.4 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFQ94882.1 - 1.8e-08 34.8 0.9 5.6e-08 33.3 0.9 1.9 1 0 0 1 1 1 1 PH domain tRNA_bind_3 PF17176.4 KFQ94882.1 - 0.043 14.1 0.7 0.13 12.6 0.7 1.7 1 0 0 1 1 1 0 tRNA-binding domain PH_11 PF15413.6 KFQ94882.1 - 0.047 14.1 3.8 4.2 7.9 3.8 2.9 1 1 0 1 1 1 0 Pleckstrin homology domain PDEase_I PF00233.19 KFQ94883.1 - 5.6e-81 271.8 1.6 3.6e-80 269.1 0.6 2.1 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 KFQ94883.1 - 2.4e-38 131.8 0.0 4.8e-18 66.1 0.0 2.5 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 KFQ94883.1 - 5.1e-16 59.2 0.0 5.6e-07 29.9 0.0 2.5 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 KFQ94883.1 - 1.3e-10 41.7 0.0 9.9e-06 25.9 0.0 4.0 2 2 0 2 2 2 2 GAF domain dCache_1 PF02743.18 KFQ94883.1 - 0.0085 15.9 0.1 5.6 6.7 0.0 2.5 2 0 0 2 2 2 2 Cache domain HD PF01966.22 KFQ94883.1 - 0.032 14.5 0.1 0.076 13.2 0.1 1.7 1 0 0 1 1 1 0 HD domain TPR_19 PF14559.6 KFQ94884.1 - 3.1e-09 37.2 1.2 0.0037 17.7 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ94884.1 - 1.2e-07 31.2 9.1 0.39 10.6 0.1 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ94884.1 - 1.6e-07 31.5 2.9 8.5 6.7 0.0 6.4 4 2 3 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ94884.1 - 1.9e-07 30.7 12.3 1 9.7 0.0 7.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ94884.1 - 5.4e-06 26.2 3.8 0.27 11.5 0.0 5.4 5 0 0 5 5 4 1 Tetratricopeptide repeat WXG100 PF06013.12 KFQ94884.1 - 0.0025 18.0 0.3 0.01 16.0 0.0 2.1 2 0 0 2 2 2 1 Proteins of 100 residues with WXG ANAPC3 PF12895.7 KFQ94884.1 - 0.0034 17.6 2.5 0.029 14.6 0.9 4.3 7 0 0 7 7 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KFQ94884.1 - 0.0046 17.7 0.9 1.3e+02 3.8 0.1 5.7 6 1 1 7 7 6 0 Tetratricopeptide repeat SNAP PF14938.6 KFQ94884.1 - 0.012 15.0 5.5 0.74 9.2 0.3 2.4 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP DASH_Dad2 PF08654.10 KFQ94884.1 - 0.023 15.1 0.5 0.083 13.3 0.1 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad2 TPR_10 PF13374.6 KFQ94884.1 - 0.033 14.1 1.6 4.4 7.3 0.0 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ94884.1 - 0.05 13.6 5.1 2.4 8.4 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF285 PF03382.14 KFQ94884.1 - 0.073 12.8 2.2 0.11 12.3 0.9 1.7 1 1 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 TPR_16 PF13432.6 KFQ94884.1 - 0.082 13.6 1.1 6.7 7.4 0.1 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFQ94884.1 - 0.52 11.1 3.5 10 7.0 0.0 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat CC2-LZ PF16516.5 KFQ94884.1 - 2.8 8.4 7.1 0.53 10.7 0.6 2.9 3 0 0 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator FAD-oxidase_C PF02913.19 KFQ94885.1 - 3.9e-58 197.0 0.0 5.2e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KFQ94885.1 - 1.3e-37 128.6 0.0 6.6e-37 126.3 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KFQ94885.1 - 0.083 13.0 0.0 0.27 11.4 0.0 1.8 1 0 0 1 1 1 0 Berberine and berberine like Tom37 PF10568.9 KFQ94887.1 - 3.8e-30 104.7 0.1 1.1e-29 103.3 0.0 1.7 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KFQ94887.1 - 1.1e-24 87.0 0.0 2.1e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KFQ94887.1 - 1.3e-24 85.8 0.2 3.6e-24 84.3 0.2 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFQ94887.1 - 7.5e-07 29.1 0.0 1.9e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFQ94887.1 - 0.046 13.9 0.1 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Homeodomain PF00046.29 KFQ94888.1 - 2.7e-22 78.3 9.1 5e-22 77.5 9.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ94888.1 - 0.068 13.1 0.9 0.14 12.1 0.9 1.5 1 0 0 1 1 1 0 Homeobox KN domain DUF2209 PF09974.9 KFQ94888.1 - 0.077 13.3 0.1 0.11 12.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Homeodomain PF00046.29 KFQ94890.1 - 1.5e-20 72.8 9.6 1.7e-20 72.6 6.1 2.3 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KFQ94890.1 - 0.013 15.4 1.8 0.031 14.2 0.3 2.4 2 0 0 2 2 2 0 Homeobox KN domain Histone PF00125.24 KFQ94890.1 - 0.77 10.1 5.3 1.7 9.0 0.0 2.9 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 DUF3528 PF12045.8 KFQ94891.1 - 5.7e-61 205.3 0.5 9.8e-61 204.5 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3528) Homeodomain PF00046.29 KFQ94891.1 - 2.2e-20 72.2 8.3 4e-20 71.4 8.3 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ94891.1 - 0.023 14.6 0.6 0.069 13.1 0.6 1.8 1 0 0 1 1 1 0 Homeobox KN domain DUF3544 PF12064.8 KFQ94891.1 - 0.097 12.9 3.7 0.15 12.3 3.7 1.2 1 0 0 1 1 1 0 Protein kinase C-binding protein 1 Homeodomain PF00046.29 KFQ94892.1 - 1.9e-20 72.4 10.8 2.1e-20 72.3 10.8 1.0 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 KFQ94892.1 - 0.0029 17.1 0.3 0.004 16.6 0.3 1.2 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 KFQ94892.1 - 0.01 15.7 5.3 0.026 14.4 5.3 1.9 1 1 0 1 1 1 0 Homeobox KN domain NUDIX PF00293.28 KFQ94893.1 - 2.2e-18 66.6 0.1 1.9e-17 63.6 0.0 2.4 3 0 0 3 3 3 1 NUDIX domain Ank_2 PF12796.7 KFQ94893.1 - 4.3e-11 43.2 0.2 1.6e-10 41.4 0.2 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFQ94893.1 - 3.3e-09 36.8 0.1 7.1e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-NADH-PPase PF09297.11 KFQ94893.1 - 6.5e-08 32.1 0.5 1.1e-07 31.3 0.5 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Ank_4 PF13637.6 KFQ94893.1 - 1.3e-07 32.0 0.7 2.9e-05 24.5 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) NUDIX-like PF09296.11 KFQ94893.1 - 2.5e-07 31.3 0.0 4.8e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain Ank PF00023.30 KFQ94893.1 - 4.6e-06 26.8 0.4 0.00016 22.0 0.0 3.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 KFQ94893.1 - 2e-05 24.6 0.2 0.00038 20.7 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat DNA_ligase_ZBD PF03119.16 KFQ94893.1 - 0.18 11.9 0.8 0.54 10.3 0.8 1.9 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain PH PF00169.29 KFQ94894.1 - 6.7e-29 100.5 1.0 8.7e-17 61.5 0.2 2.6 3 0 0 3 3 3 2 PH domain PDZ PF00595.24 KFQ94894.1 - 8.5e-14 51.7 0.0 1.5e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFQ94894.1 - 1.2e-11 44.2 0.3 2.1e-11 43.5 0.3 1.3 1 0 0 1 1 1 1 PDZ domain PH_11 PF15413.6 KFQ94894.1 - 4.8e-10 39.8 11.5 0.00041 20.7 7.1 4.4 2 2 1 3 3 3 3 Pleckstrin homology domain PDZ_2 PF13180.6 KFQ94894.1 - 3e-07 30.7 0.0 6.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PH_8 PF15409.6 KFQ94894.1 - 4.3e-07 30.1 0.7 2e-05 24.8 0.5 3.0 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 KFQ94894.1 - 0.013 15.6 0.1 0.21 11.7 0.0 2.4 2 0 0 2 2 2 0 PH domain PH_9 PF15410.6 KFQ94894.1 - 0.019 15.3 0.4 18 5.8 0.1 3.5 2 2 1 3 3 3 0 Pleckstrin homology domain PH_15 PF17339.2 KFQ94894.1 - 0.11 12.4 0.1 0.56 10.1 0.0 2.0 2 0 0 2 2 2 0 PH domain RVT_1 PF00078.27 KFQ94895.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.4 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) UNC119_bdg PF15435.6 KFQ94896.1 - 2.9e-109 363.2 0.4 3.2e-109 363.0 0.4 1.0 1 0 0 1 1 1 1 UNC119-binding protein C5orf30 homologue Integrase_H2C2 PF17921.1 KFQ94897.1 - 3.9e-16 58.9 1.3 9.2e-16 57.7 1.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KFQ94897.1 - 1.5e-06 28.4 0.1 1.1e-05 25.6 0.0 2.4 2 1 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 KFQ94897.1 - 7e-05 23.0 0.8 0.00016 21.8 0.8 1.7 1 0 0 1 1 1 1 H2C2 zinc finger AbiJ_NTD4 PF18863.1 KFQ94897.1 - 0.00056 20.4 1.9 0.0034 17.9 0.2 2.4 2 1 0 2 2 2 1 AbiJ N-terminal domain 4 Pox_A3L PF05288.11 KFQ94897.1 - 0.085 12.9 1.6 0.61 10.1 0.1 2.7 3 0 0 3 3 3 0 Poxvirus A3L Protein RNA_POL_M_15KD PF02150.16 KFQ94897.1 - 0.15 11.9 0.2 0.37 10.7 0.2 1.6 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit Cu2_monoox_C PF03712.15 KFQ94898.1 - 2.6e-44 150.5 0.2 4.8e-44 149.6 0.2 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 KFQ94898.1 - 4.1e-25 88.5 0.0 8.7e-25 87.5 0.0 1.6 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain NHL PF01436.21 KFQ94898.1 - 5e-19 67.3 8.2 2.6e-05 24.0 0.1 6.2 6 0 0 6 6 6 4 NHL repeat DUF2207 PF09972.9 KFQ94898.1 - 0.11 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SGL PF08450.12 KFQ94898.1 - 0.16 11.5 0.0 16 5.0 0.0 2.5 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region LMBR1 PF04791.16 KFQ94898.1 - 0.17 10.7 0.0 0.17 10.7 0.0 1.5 2 0 0 2 2 2 0 LMBR1-like membrane protein OATP PF03137.20 KFQ94899.1 - 4e-26 91.4 0.1 4e-26 91.4 0.1 1.4 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Sec62 PF03839.16 KFQ94899.1 - 0.16 11.5 0.2 0.21 11.1 0.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Spin-Ssty PF02513.17 KFQ94900.1 - 9.1e-77 252.6 7.8 5.8e-28 96.4 0.2 3.1 3 0 0 3 3 3 3 Spin/Ssty Family Pou PF00157.17 KFQ94901.1 - 6.2e-24 83.8 2.6 3.4e-14 52.6 0.1 3.0 3 0 0 3 3 3 2 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KFQ94901.1 - 1.1e-17 63.6 0.9 1.1e-17 63.6 0.9 2.1 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KFQ94901.1 - 0.0067 16.3 0.2 0.052 13.5 0.0 2.4 2 0 0 2 2 2 1 Homeobox KN domain HOCHOB PF17943.1 KFQ94901.1 - 0.0074 17.0 0.1 0.016 15.9 0.1 1.5 1 0 0 1 1 1 1 Homeobox-cysteine loop-homeobox FtsX_ECD PF18075.1 KFQ94901.1 - 0.025 15.2 0.0 0.025 15.2 0.0 3.0 3 0 0 3 3 3 0 FtsX extracellular domain CLN3 PF02487.17 KFQ94901.1 - 0.19 10.7 4.1 0.44 9.5 4.1 1.5 1 0 0 1 1 1 0 CLN3 protein DUF4179 PF13786.6 KFQ94901.1 - 0.35 11.4 2.1 1.7 9.2 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) V_ATPase_I PF01496.19 KFQ94901.1 - 3.3 5.5 6.6 5.8 4.7 6.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Macoilin PF09726.9 KFQ94901.1 - 9.8 4.6 17.2 1.2 7.5 8.9 2.2 2 0 0 2 2 2 0 Macoilin family Clathrin PF00637.20 KFQ94902.1 - 5.9e-27 94.3 1.0 5.9e-27 94.3 1.0 2.7 3 0 0 3 3 3 1 Region in Clathrin and VPS Vps39_1 PF10366.9 KFQ94902.1 - 0.00034 20.9 4.9 0.0023 18.2 0.1 3.4 3 1 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KFQ94902.1 - 0.00038 20.9 0.2 0.0012 19.2 0.2 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 ANAPC4_WD40 PF12894.7 KFQ94902.1 - 0.0015 18.8 0.2 0.34 11.2 0.0 3.2 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_5 PF14634.6 KFQ94902.1 - 0.012 15.6 5.0 0.04 13.9 5.0 2.0 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 KFQ94902.1 - 0.19 12.1 11.3 0.03 14.7 6.4 2.4 2 0 0 2 2 2 0 Ring finger domain zf-rbx1 PF12678.7 KFQ94902.1 - 0.23 11.8 4.1 0.92 9.8 4.1 2.1 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3H2C3 PF17122.5 KFQ94902.1 - 0.47 10.5 5.8 0.49 10.5 3.9 2.1 1 1 0 1 1 1 0 Zinc-finger zf-RING_11 PF17123.5 KFQ94902.1 - 0.69 9.7 8.2 0.24 11.2 4.5 2.2 2 0 0 2 2 2 0 RING-like zinc finger PHD PF00628.29 KFQ94902.1 - 0.79 9.7 3.4 2.5 8.0 3.4 2.0 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.6 KFQ94902.1 - 3 7.9 6.1 18 5.4 6.0 2.3 1 1 0 1 1 1 0 RING-type zinc-finger Sushi PF00084.20 KFQ94903.1 - 6.9e-26 90.6 12.6 1.1e-08 35.5 1.0 3.0 3 0 0 3 3 3 3 Sushi repeat (SCR repeat) cEGF PF12662.7 KFQ94903.1 - 0.0081 16.1 4.9 6.4 6.8 0.0 3.8 3 1 0 3 3 3 2 Complement Clr-like EGF-like HRM PF02793.22 KFQ94903.1 - 0.092 13.1 5.7 0.35 11.2 0.1 2.6 2 1 0 2 2 2 0 Hormone receptor domain CBM_14 PF01607.24 KFQ94903.1 - 0.66 10.2 6.0 5.5 7.2 0.4 3.0 3 0 0 3 3 3 0 Chitin binding Peritrophin-A domain Sushi PF00084.20 KFQ94904.1 - 5.2e-36 123.0 14.1 4.4e-13 49.6 0.6 3.0 3 0 0 3 3 3 3 Sushi repeat (SCR repeat) HRM PF02793.22 KFQ94904.1 - 0.00031 21.0 7.0 0.14 12.5 0.2 3.4 2 1 1 3 3 3 2 Hormone receptor domain cEGF PF12662.7 KFQ94904.1 - 0.01 15.8 4.2 9 6.3 0.0 3.8 3 1 0 3 3 3 0 Complement Clr-like EGF-like CBM_14 PF01607.24 KFQ94904.1 - 0.2 11.8 5.1 8.9 6.6 0.5 2.9 3 0 0 3 3 3 0 Chitin binding Peritrophin-A domain Sushi PF00084.20 KFQ94905.1 - 1.6e-15 57.4 0.8 1.1e-11 45.1 0.2 2.1 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) Sushi PF00084.20 KFQ94906.1 - 5.7e-38 129.3 10.9 5.6e-13 49.3 0.7 3.0 3 0 0 3 3 3 3 Sushi repeat (SCR repeat) Sortilin_C PF15901.5 KFQ94906.1 - 0.018 15.4 1.2 0.85 9.9 0.2 2.8 1 1 1 3 3 3 0 Sortilin, neurotensin receptor 3, C-terminal cEGF PF12662.7 KFQ94906.1 - 0.027 14.4 9.0 0.99 9.4 0.4 3.6 3 0 0 3 3 3 0 Complement Clr-like EGF-like HRM PF02793.22 KFQ94906.1 - 0.082 13.2 9.4 0.37 11.1 0.5 3.2 2 1 1 3 3 3 0 Hormone receptor domain Sushi PF00084.20 KFQ94907.1 - 1.1e-14 54.7 5.4 3.3e-11 43.6 2.0 2.0 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) Sushi PF00084.20 KFQ94908.1 - 4.6e-20 72.0 3.2 2.6e-09 37.6 0.2 2.1 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) Sushi PF00084.20 KFQ94909.1 - 6.2e-16 58.7 2.3 4.3e-12 46.4 0.4 2.1 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) Sushi PF00084.20 KFQ94910.1 - 3.4e-54 181.3 32.8 9.4e-14 51.8 0.8 6.4 6 1 0 6 6 6 6 Sushi repeat (SCR repeat) FeoB_associated PF12669.7 KFQ94910.1 - 0.047 14.1 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Plexin_cytopl PF08337.12 KFQ94911.1 - 7e-260 863.4 0.2 8.5e-260 863.2 0.2 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.24 KFQ94911.1 - 4.3e-36 122.9 10.5 5.5e-09 36.0 0.0 6.4 6 0 0 6 6 6 4 IPT/TIG domain TIG_2 PF18020.1 KFQ94911.1 - 3.4e-32 110.9 0.0 3.4e-31 107.7 0.0 2.7 2 0 0 2 2 2 1 TIG domain found in plexin TIG_plexin PF17960.1 KFQ94911.1 - 1e-24 86.3 3.9 7.3e-22 77.2 0.0 4.6 4 0 0 4 4 4 2 TIG domain PSI PF01437.25 KFQ94911.1 - 5.1e-20 71.7 57.3 7.7e-10 39.2 13.6 3.6 3 0 0 3 3 3 3 Plexin repeat RasGAP PF00616.19 KFQ94911.1 - 0.00031 20.5 1.0 0.1 12.3 1.5 2.6 2 1 0 2 2 2 2 GTPase-activator protein for Ras-like GTPase PSI_integrin PF17205.3 KFQ94911.1 - 0.0063 16.2 46.1 0.0078 15.9 9.3 3.7 3 0 0 3 3 3 2 Integrin plexin domain Sema PF01403.19 KFQ94912.1 - 9.6e-63 212.5 0.0 1.1e-62 212.2 0.0 1.1 1 0 0 1 1 1 1 Sema domain Pkinase PF00069.25 KFQ94913.1 - 1.3e-76 257.4 0.0 1.6e-76 257.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ94913.1 - 5e-33 114.5 0.0 6.1e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ94913.1 - 1.7e-09 37.5 0.0 2.5e-09 36.9 0.0 1.4 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 KFQ94913.1 - 5.4e-05 22.6 0.0 7.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFQ94913.1 - 0.00035 19.5 0.0 0.00091 18.1 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 KFQ94913.1 - 0.0006 19.5 0.1 0.00089 18.9 0.1 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KFQ94913.1 - 0.0042 17.0 0.0 0.13 12.1 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family CsgA PF17334.2 KFQ94913.1 - 0.033 14.9 0.7 0.57 11.0 0.0 2.7 3 0 0 3 3 3 0 Minor curli fiber component A YrbL-PhoP_reg PF10707.9 KFQ94913.1 - 0.095 12.2 0.1 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Laminin_N PF00055.17 KFQ94914.1 - 4.6e-53 180.2 0.0 4.6e-53 180.2 0.0 2.9 3 1 1 4 4 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 KFQ94914.1 - 8.4e-48 160.3 132.0 4.8e-11 42.6 10.1 7.3 7 1 0 7 7 6 6 Laminin EGF domain DUF948 PF06103.11 KFQ94914.1 - 0.0076 16.5 17.2 0.089 13.1 0.3 5.2 4 1 1 5 5 5 2 Bacterial protein of unknown function (DUF948) Alanine_zipper PF11839.8 KFQ94914.1 - 0.013 15.9 3.2 0.013 15.9 3.2 3.4 3 0 0 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein F5_F8_type_C PF00754.25 KFQ94914.1 - 0.02 15.0 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 F5/8 type C domain NPV_P10 PF05531.12 KFQ94914.1 - 0.028 14.9 8.7 2.4 8.7 0.0 5.4 3 1 3 6 6 6 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 KFQ94914.1 - 0.48 10.5 24.6 0.2 11.7 1.2 4.7 2 2 1 4 4 4 0 Laminin Domain II Sec34 PF04136.15 KFQ94914.1 - 0.8 9.6 18.6 1.9 8.4 0.0 5.4 4 1 0 5 5 5 0 Sec34-like family Tropomyosin_1 PF12718.7 KFQ94914.1 - 2.2 8.4 24.4 0.074 13.2 0.7 4.4 4 1 1 5 5 5 0 Tropomyosin like Cauli_AT PF03233.13 KFQ94914.1 - 2.4 8.0 6.5 2.2 8.2 0.2 3.1 2 1 0 3 3 3 0 Aphid transmission protein DUF1664 PF07889.12 KFQ94914.1 - 3.1 7.9 20.6 2.9 8.0 0.7 5.2 3 2 3 6 6 6 0 Protein of unknown function (DUF1664) G0-G1_switch_2 PF15103.6 KFQ94915.1 - 2.7e-42 143.5 0.7 3e-42 143.3 0.7 1.0 1 0 0 1 1 1 1 G0/G1 switch protein 2 adh_short PF00106.25 KFQ94916.1 - 5.1e-45 153.3 0.2 5.9e-45 153.1 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFQ94916.1 - 8.4e-23 81.1 0.0 9.4e-23 81.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFQ94916.1 - 1.2e-08 35.1 1.1 9e-08 32.2 1.1 1.9 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KFQ94916.1 - 0.0037 17.3 0.2 0.0058 16.7 0.2 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.10 KFQ94916.1 - 0.0079 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 KFQ94916.1 - 0.024 14.0 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_2 PF03446.15 KFQ94916.1 - 0.034 14.3 0.1 0.052 13.7 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase FMO-like PF00743.19 KFQ94916.1 - 0.043 12.2 0.0 0.06 11.8 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like 2-Hacid_dh_C PF02826.19 KFQ94916.1 - 0.082 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 KFQ94917.1 - 3e-44 150.8 0.1 3.8e-44 150.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFQ94917.1 - 2.2e-24 86.3 0.0 2.8e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFQ94917.1 - 9.1e-07 29.0 0.4 0.0073 16.2 0.1 2.1 2 0 0 2 2 2 2 KR domain DUF1776 PF08643.10 KFQ94917.1 - 6e-05 22.6 0.0 8.3e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 KFQ94917.1 - 0.029 13.7 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 KFQ94917.1 - 0.12 12.4 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF4504 PF14953.6 KFQ94918.1 - 4.5e-38 131.1 0.0 4.9e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4504) DUF2156 PF09924.9 KFQ94918.1 - 0.084 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) IRF-3 PF10401.9 KFQ94919.1 - 2.8e-16 59.8 0.0 3.8e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 EF-hand_1 PF00036.32 KFQ94920.1 - 3.4e-23 79.4 10.0 1.4e-06 27.4 0.0 4.5 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 KFQ94920.1 - 5.4e-21 74.8 1.8 5.7e-14 52.3 0.1 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFQ94920.1 - 3.4e-20 70.2 4.5 4.5e-05 23.0 0.1 4.8 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 KFQ94920.1 - 1.4e-15 56.0 10.0 9.8e-05 21.7 0.6 4.5 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 KFQ94920.1 - 2.6e-15 56.0 2.4 5.3e-07 29.4 0.1 3.9 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFQ94920.1 - 5.1e-07 30.0 0.3 0.22 11.8 0.0 3.2 1 1 2 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFQ94920.1 - 0.0067 16.4 1.9 2.8 7.9 0.2 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KFQ94921.1 - 1.3e-22 77.6 11.6 7.2e-07 28.3 0.2 4.8 4 1 1 5 5 5 3 EF hand EF-hand_7 PF13499.6 KFQ94921.1 - 4.1e-21 75.2 3.8 5.2e-14 52.5 0.3 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KFQ94921.1 - 1.3e-20 71.5 5.5 1.9e-05 24.2 0.0 4.6 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KFQ94921.1 - 7e-18 64.2 2.9 1.9e-08 34.0 0.6 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFQ94921.1 - 2.3e-14 52.1 9.1 8.5e-06 25.0 0.9 4.2 4 1 1 5 5 5 3 EF hand SPARC_Ca_bdg PF10591.9 KFQ94921.1 - 2.4e-07 31.0 0.5 0.00043 20.6 0.1 2.9 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFQ94921.1 - 6e-06 26.2 2.6 0.13 12.3 0.1 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KFQ94921.1 - 6.2e-05 23.1 0.5 0.018 15.2 0.3 2.7 2 1 0 2 2 2 1 Dockerin type I domain DUF4891 PF16232.5 KFQ94921.1 - 0.037 14.5 0.0 3.4 8.2 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4891) EF-hand_10 PF14788.6 KFQ94921.1 - 0.056 13.3 1.4 1.7 8.5 0.4 2.3 2 0 0 2 2 2 0 EF hand VCBS PF13517.6 KFQ94921.1 - 0.083 13.5 2.7 9.8 6.9 0.1 3.0 2 1 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella WD40 PF00400.32 KFQ94923.1 - 2.6e-10 40.7 17.3 0.00018 22.2 0.3 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ94923.1 - 6.8e-06 26.3 0.1 1.4 9.3 0.0 3.5 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 KFQ94923.1 - 0.0016 18.4 0.5 0.0068 16.4 0.5 1.9 1 1 0 1 1 1 1 Transcription factor IIIC subunit delta N-term MMS1_N PF10433.9 KFQ94923.1 - 0.073 11.7 0.0 0.088 11.4 0.0 1.1 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Mt_ATP-synt_B PF05405.14 KFQ94924.1 - 1.3e-51 174.4 10.2 1.5e-51 174.3 10.2 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) R_equi_Vir PF05526.11 KFQ94924.1 - 0.15 11.9 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein 7tm_1 PF00001.21 KFQ94925.1 - 2.4e-43 148.4 19.1 2.8e-43 148.2 19.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ94925.1 - 1.9e-11 43.8 19.4 2.3e-11 43.6 19.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFQ94925.1 - 1.9e-08 34.4 11.0 2.2e-08 34.2 11.0 1.4 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFQ94925.1 - 2.5e-05 24.0 17.4 2.5e-05 24.0 17.4 1.5 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF3399 PF11879.8 KFQ94926.1 - 1.2e-46 157.2 11.1 1.2e-46 157.2 11.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3399) Ion_trans PF00520.31 KFQ94926.1 - 2.2e-06 27.1 0.0 2.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFQ94926.1 - 0.001 19.0 0.1 0.0016 18.4 0.1 1.3 1 0 0 1 1 1 1 Ion channel DUF702 PF05142.12 KFQ94926.1 - 0.31 11.5 6.3 0.06 13.8 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF702) BTB_2 PF02214.22 KFQ94927.1 - 2.3e-29 101.6 0.1 4.8e-29 100.6 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.31 KFQ94927.1 - 7.1e-29 100.8 14.0 1.2e-28 100.0 14.0 1.3 1 0 0 1 1 1 1 Ion transport protein BTB_3 PF16017.5 KFQ94927.1 - 2.3e-05 24.4 0.0 6.2e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Shal-type PF11601.8 KFQ94927.1 - 0.00093 18.7 6.9 0.0017 17.8 6.9 1.4 1 0 0 1 1 1 1 Shal-type voltage-gated potassium channels, N-terminal PKD_channel PF08016.12 KFQ94927.1 - 0.1 11.3 10.8 0.19 10.4 10.7 1.5 1 1 0 1 1 1 0 Polycystin cation channel Ion_trans_2 PF07885.16 KFQ94927.1 - 1.4 8.9 14.7 0.061 13.3 4.3 2.8 3 0 0 3 3 3 0 Ion channel CortBP2 PF09727.9 KFQ94928.1 - 2.3e-68 229.9 19.8 2.3e-68 229.9 19.8 2.5 2 0 0 2 2 2 1 Cortactin-binding protein-2 hDGE_amylase PF14701.6 KFQ94928.1 - 0.55 9.3 9.8 1 8.4 9.8 1.4 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain DUF812 PF05667.11 KFQ94928.1 - 0.95 8.3 31.7 2 7.2 31.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF3037 PF11236.8 KFQ94928.1 - 1.5 9.3 13.6 0.39 11.1 0.5 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3037) Rootletin PF15035.6 KFQ94928.1 - 4.3 7.3 37.6 4.1 7.4 14.5 2.7 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion LMBR1 PF04791.16 KFQ94928.1 - 6.9 5.5 11.4 10 4.9 11.4 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein wnt PF00110.19 KFQ94929.1 - 2.4e-124 414.9 29.1 2.8e-124 414.7 29.1 1.0 1 0 0 1 1 1 1 wnt family ST7 PF04184.12 KFQ94930.1 - 6.4e-286 949.0 1.5 7.2e-286 948.8 1.5 1.0 1 0 0 1 1 1 1 ST7 protein TPR_6 PF13174.6 KFQ94930.1 - 0.0018 18.8 0.3 0.0089 16.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ94930.1 - 0.028 14.5 4.5 2 8.8 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ94930.1 - 0.033 14.0 4.4 11 6.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Clathrin PF00637.20 KFQ94930.1 - 0.034 14.0 0.2 0.074 12.9 0.2 1.5 1 0 0 1 1 1 0 Region in Clathrin and VPS TPR_8 PF13181.6 KFQ94930.1 - 0.16 12.3 1.8 21 5.6 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ94930.1 - 0.2 12.2 0.1 0.2 12.2 0.1 3.7 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ94930.1 - 2.7 9.0 11.9 18 6.5 0.7 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat F-actin_cap_A PF01267.17 KFQ94931.1 - 9.4e-106 353.1 0.6 1.1e-105 352.9 0.6 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit CCP_MauG PF03150.14 KFQ94931.1 - 0.0069 17.0 0.1 0.088 13.4 0.1 2.4 1 1 1 2 2 2 1 Di-haem cytochrome c peroxidase DUF5011 PF16403.5 KFQ94931.1 - 0.29 11.3 1.6 0.7 10.1 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5011) Ras PF00071.22 KFQ94933.1 - 3.1e-58 196.0 0.0 3.5e-58 195.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ94933.1 - 2.5e-23 82.6 0.0 3.4e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ94933.1 - 2.3e-10 40.2 0.0 4.1e-10 39.4 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFQ94933.1 - 0.00015 21.4 0.0 0.00029 20.4 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFQ94933.1 - 0.042 13.3 0.0 0.069 12.6 0.0 1.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFQ94933.1 - 0.043 13.2 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PP2C PF00481.21 KFQ94934.1 - 1.8e-28 99.9 0.0 3.5e-13 49.8 0.0 3.1 3 0 0 3 3 3 3 Protein phosphatase 2C SpoIIE PF07228.12 KFQ94934.1 - 4.9e-05 23.3 0.0 0.022 14.7 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) TAFA PF12020.8 KFQ94935.1 - 4.7e-33 113.5 8.3 5.2e-33 113.4 8.3 1.0 1 0 0 1 1 1 1 TAFA family MFS_1 PF07690.16 KFQ94936.1 - 4.6e-37 127.8 36.3 1.3e-30 106.5 26.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Connexin PF00029.19 KFQ94936.1 - 0.13 12.0 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 Connexin Ycf70 PF17382.2 KFQ94936.1 - 0.17 12.3 2.3 1.1 9.7 0.1 2.8 2 0 0 2 2 2 0 Uncharacterized Ycf70-like LRR_8 PF13855.6 KFQ94937.1 - 1.6e-63 210.3 35.0 3.7e-16 58.6 3.8 6.9 3 1 2 6 6 6 5 Leucine rich repeat I-set PF07679.16 KFQ94937.1 - 1.8e-48 162.5 0.0 2.3e-20 72.5 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ94937.1 - 1.3e-44 150.7 0.0 6.3e-14 52.3 0.1 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFQ94937.1 - 5.8e-31 106.7 0.0 1.6e-09 37.9 0.3 3.4 3 0 0 3 3 3 3 Immunoglobulin domain LRR_4 PF12799.7 KFQ94937.1 - 1.6e-28 98.3 40.5 7.6e-06 26.2 0.9 9.2 3 2 8 11 11 11 10 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFQ94937.1 - 1.1e-27 96.5 0.1 1.5e-11 44.3 0.0 3.3 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) ig PF00047.25 KFQ94937.1 - 4.6e-26 90.8 0.0 3.2e-07 30.4 0.2 3.4 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFQ94937.1 - 2.8e-14 53.2 2.0 0.00012 22.2 0.7 5.7 3 3 0 3 3 3 3 Immunoglobulin V-set domain LRR_9 PF14580.6 KFQ94937.1 - 2.8e-12 46.5 13.3 0.00063 19.3 0.5 5.2 1 1 4 5 5 5 5 Leucine-rich repeat LRR_1 PF00560.33 KFQ94937.1 - 2.5e-10 39.5 27.0 0.086 13.4 0.4 11.2 12 1 0 12 12 10 2 Leucine Rich Repeat C2-set_2 PF08205.12 KFQ94937.1 - 2.6e-10 40.2 0.0 0.0017 18.4 0.0 3.6 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFQ94937.1 - 2.7e-08 34.1 0.0 0.042 14.2 0.0 4.1 3 1 0 3 3 3 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFQ94937.1 - 3.2e-06 26.6 0.0 0.74 9.4 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain LRRCT PF01463.24 KFQ94937.1 - 5.2e-05 23.5 0.0 0.00014 22.1 0.0 1.8 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain Izumo-Ig PF16706.5 KFQ94937.1 - 0.00011 22.1 1.6 3.3 7.8 0.0 4.2 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain C1-set PF07654.15 KFQ94937.1 - 0.0045 17.3 0.1 0.073 13.5 0.3 2.8 3 0 0 3 3 3 1 Immunoglobulin C1-set domain ABATE PF07336.11 KFQ94937.1 - 0.19 12.4 0.5 18 6.0 0.0 2.4 1 1 1 2 2 2 0 Putative stress-induced transcription regulator LRR_6 PF13516.6 KFQ94937.1 - 1.3 9.3 50.1 2.3 8.5 0.5 11.9 15 0 0 15 15 13 0 Leucine Rich repeat PDZ PF00595.24 KFQ94938.1 - 1.2e-64 214.6 8.1 2.5e-15 56.6 0.0 5.5 5 0 0 5 5 5 5 PDZ domain PDZ_6 PF17820.1 KFQ94938.1 - 3.5e-43 145.2 16.5 1.7e-10 40.5 0.7 5.5 5 0 0 5 5 5 5 PDZ domain PDZ_2 PF13180.6 KFQ94938.1 - 4.1e-25 87.9 0.1 0.00016 22.0 0.0 5.4 5 0 0 5 5 5 5 PDZ domain WW PF00397.26 KFQ94938.1 - 2.5e-17 62.6 5.3 1.3e-08 34.8 0.1 2.4 2 0 0 2 2 2 2 WW domain Guanylate_kin PF00625.21 KFQ94938.1 - 2.8e-10 40.2 0.0 5.4e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase MAGI_u1 PF16663.5 KFQ94938.1 - 1.5e-05 25.0 6.0 1.5e-05 25.0 6.0 2.5 2 0 0 2 2 2 1 Unstructured region on MAGI Tricorn_PDZ PF14685.6 KFQ94938.1 - 1.6e-05 24.8 5.7 0.25 11.3 0.1 4.8 5 0 0 5 5 5 2 Tricorn protease PDZ domain OB_RNB PF08206.11 KFQ94938.1 - 0.069 12.8 1.1 49 3.7 0.0 4.1 4 0 0 4 4 4 0 Ribonuclease B OB domain Phtf-FEM1B_bdg PF12129.8 KFQ94939.1 - 4.7e-70 234.4 3.0 1.4e-69 232.8 3.0 1.9 1 0 0 1 1 1 1 Male germ-cell putative homeodomain transcription factor Y_phosphatase PF00102.27 KFQ94941.1 - 1.2e-78 263.9 0.1 1.7e-78 263.4 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFQ94941.1 - 0.0017 18.4 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KFQ94941.1 - 0.03 14.2 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF3209 PF11483.8 KFQ94941.1 - 0.17 12.3 0.0 0.5 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3209) DRMBL PF07522.14 KFQ94943.1 - 2e-10 40.8 0.2 4.4e-10 39.7 0.2 1.7 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase RMMBL PF07521.12 KFQ94943.1 - 0.095 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Pkinase PF00069.25 KFQ94944.1 - 8.2e-51 172.9 0.0 1.5e-50 172.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ94944.1 - 3.3e-24 85.6 0.0 5.2e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFQ94944.1 - 1.3e-05 24.7 0.0 3.2e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFQ94944.1 - 0.0094 14.8 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFQ94944.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KFQ94944.1 - 0.02 13.9 0.1 0.035 13.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase C2 PF00168.30 KFQ94945.1 - 1.7e-54 182.4 0.0 6.6e-26 90.6 0.0 3.1 3 0 0 3 3 3 2 C2 domain CEP76-C2 PF15627.6 KFQ94945.1 - 0.00036 20.1 0.0 0.052 13.1 0.0 2.7 3 0 0 3 3 3 2 CEP76 C2 domain PI3K_C2 PF00792.24 KFQ94945.1 - 0.00037 20.4 0.1 0.12 12.3 0.0 3.0 4 0 0 4 4 4 2 Phosphoinositide 3-kinase C2 DOCK-C2 PF14429.6 KFQ94945.1 - 0.039 13.8 0.0 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins Bromodomain PF00439.25 KFQ94946.1 - 2.9e-23 81.7 0.3 9.8e-23 80.0 0.3 2.0 1 0 0 1 1 1 1 Bromodomain zf-B_box PF00643.24 KFQ94946.1 - 5e-12 45.8 19.8 1.7e-09 37.7 6.7 4.9 6 0 0 6 6 6 2 B-box zinc finger PHD PF00628.29 KFQ94946.1 - 4.1e-08 33.0 9.5 4.1e-08 33.0 9.5 4.5 5 0 0 5 5 5 1 PHD-finger Exonuc_VII_L PF02601.15 KFQ94946.1 - 5.9 6.4 9.6 7 6.1 3.9 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit BCAS2 PF05700.11 KFQ94947.1 - 2.1e-56 190.9 13.3 2.3e-56 190.7 13.3 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) EzrA PF06160.12 KFQ94947.1 - 0.00067 18.0 8.0 0.00084 17.6 8.0 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA THOC7 PF05615.13 KFQ94947.1 - 0.00099 19.4 9.8 0.0021 18.4 1.8 2.2 1 1 1 2 2 2 1 Tho complex subunit 7 Tup_N PF08581.10 KFQ94947.1 - 0.0048 17.2 11.2 0.22 11.9 2.1 3.2 1 1 1 3 3 3 1 Tup N-terminal GAS PF13851.6 KFQ94947.1 - 0.0097 15.3 11.9 0.012 14.9 11.5 1.4 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Cep57_CLD PF14073.6 KFQ94947.1 - 0.015 15.3 10.8 0.025 14.6 10.8 1.4 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 DUF4201 PF13870.6 KFQ94947.1 - 0.021 14.6 10.6 7 6.3 4.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Filament PF00038.21 KFQ94947.1 - 0.021 14.4 11.7 0.042 13.4 11.2 1.6 1 1 1 2 2 2 0 Intermediate filament protein bZIP_1 PF00170.21 KFQ94947.1 - 0.058 13.5 3.5 6.7 6.9 0.5 2.8 2 1 0 2 2 2 0 bZIP transcription factor DUF2508 PF10704.9 KFQ94947.1 - 0.061 13.5 0.4 0.061 13.5 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) CENP-F_leu_zip PF10473.9 KFQ94947.1 - 0.087 12.9 11.3 0.22 11.5 11.0 1.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SCRG1 PF15224.6 KFQ94947.1 - 0.11 12.7 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Scrapie-responsive protein 1 Phlebovirus_NSM PF07246.11 KFQ94947.1 - 0.12 11.7 5.1 0.15 11.4 5.1 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF3450 PF11932.8 KFQ94947.1 - 0.14 11.4 11.7 0.36 10.1 4.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) OmpH PF03938.14 KFQ94947.1 - 0.14 12.5 8.1 0.17 12.2 7.4 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Cep57_MT_bd PF06657.13 KFQ94947.1 - 0.18 12.2 9.4 2.2 8.8 1.4 3.1 2 2 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 TMCO5 PF14992.6 KFQ94947.1 - 0.22 11.1 9.9 0.2 11.2 9.1 1.4 1 1 0 1 1 1 0 TMCO5 family TMF_DNA_bd PF12329.8 KFQ94947.1 - 0.24 11.4 9.4 1.2 9.2 9.3 2.2 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF724 PF05266.14 KFQ94947.1 - 0.26 11.1 7.3 0.59 9.9 7.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Uso1_p115_C PF04871.13 KFQ94947.1 - 0.33 11.3 9.0 0.62 10.4 6.4 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DivIC PF04977.15 KFQ94947.1 - 0.38 10.5 11.3 1.5 8.6 1.2 2.6 3 0 0 3 3 2 0 Septum formation initiator GIT_CC PF16559.5 KFQ94947.1 - 0.6 10.0 9.6 2.7 7.9 2.7 2.6 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cnn_1N PF07989.11 KFQ94947.1 - 0.73 10.0 10.8 2.6 8.2 2.0 2.6 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 PRKG1_interact PF15898.5 KFQ94947.1 - 0.74 10.7 12.1 0.18 12.7 6.3 2.3 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Ribosomal_L29 PF00831.23 KFQ94947.1 - 1.2 9.1 7.4 1.6 8.7 1.9 2.4 2 0 0 2 2 2 0 Ribosomal L29 protein DUF1192 PF06698.11 KFQ94947.1 - 1.5 8.9 5.9 3.1 7.9 0.4 3.3 4 0 0 4 4 3 0 Protein of unknown function (DUF1192) FlaC_arch PF05377.11 KFQ94947.1 - 2.4 8.6 8.8 2.7 8.5 0.3 2.9 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) GPS2_interact PF15784.5 KFQ94947.1 - 4.5 7.8 8.7 12 6.4 2.0 2.6 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain Spc24 PF08286.11 KFQ94947.1 - 4.9 7.5 11.4 3.4 7.9 1.2 2.7 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 ABC_tran_CTD PF16326.5 KFQ94947.1 - 5.8 7.2 11.2 9.3 6.6 2.5 3.3 2 1 1 3 3 3 0 ABC transporter C-terminal domain DUF4200 PF13863.6 KFQ94947.1 - 6 7.3 13.1 33 4.9 2.9 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) ZapB PF06005.12 KFQ94947.1 - 6.7 7.2 17.0 16 6.0 2.8 3.4 2 2 1 3 3 3 0 Cell division protein ZapB Csm1_N PF18504.1 KFQ94947.1 - 7.8 6.9 13.5 0.63 10.4 1.3 2.8 3 0 0 3 3 3 0 Csm1 N-terminal domain DENN PF02141.21 KFQ94948.1 - 4.8e-60 202.7 1.6 1e-59 201.7 1.6 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KFQ94948.1 - 2.8e-15 56.8 0.7 6.9e-15 55.5 0.7 1.8 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KFQ94948.1 - 9.4e-10 38.3 2.9 2.5e-09 36.9 2.9 1.8 1 0 0 1 1 1 1 dDENN domain A_deaminase PF00962.22 KFQ94949.1 - 2.7e-133 444.3 1.4 1.8e-132 441.6 1.4 2.0 1 1 0 1 1 1 1 Adenosine/AMP deaminase zf-CCCH_6 PF18585.1 KFQ94949.1 - 2.7 8.0 5.0 9.7 6.2 0.1 3.0 3 0 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Ras PF00071.22 KFQ94950.1 - 5.6e-43 146.4 0.1 6.3e-43 146.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ94950.1 - 2e-11 44.2 0.0 4e-11 43.2 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KFQ94950.1 - 2e-06 27.5 0.0 3.8e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KFQ94950.1 - 0.00015 21.3 0.0 0.00019 20.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFQ94950.1 - 0.0063 16.4 0.0 0.01 15.8 0.0 1.4 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KFQ94950.1 - 0.0072 15.9 0.0 0.014 15.0 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B TPP_enzyme_M PF00205.22 KFQ94950.1 - 0.18 11.5 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain CSD PF00313.22 KFQ94951.1 - 2.2e-82 270.9 16.4 7.3e-17 61.0 0.1 9.1 9 0 0 9 9 9 5 'Cold-shock' DNA-binding domain S1-like PF14444.6 KFQ94951.1 - 3.7e-13 49.2 10.8 0.053 13.5 0.0 7.3 7 0 0 7 7 7 4 S1-like SUZ-C PF12901.7 KFQ94951.1 - 1.2e-11 44.4 0.9 5.7e-11 42.2 0.1 2.3 2 0 0 2 2 2 1 SUZ-C motif CusF_Ec PF11604.8 KFQ94951.1 - 2.9e-09 36.8 7.1 0.066 13.2 0.0 7.6 8 0 0 8 8 8 3 Copper binding periplasmic protein CusF GbpA_2 PF18416.1 KFQ94951.1 - 0.00022 21.5 1.0 26 5.2 0.0 6.0 6 0 0 6 6 6 0 N-acetylglucosamine binding protein domain 2 RsgA_N PF16745.5 KFQ94951.1 - 0.0048 16.6 6.0 19 5.1 0.0 5.8 7 0 0 7 7 7 0 RsgA N-terminal domain DUF3857 PF12969.7 KFQ94951.1 - 0.019 15.0 0.1 9.4 6.3 0.0 3.8 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3857) MazE_antitoxin PF04014.18 KFQ94951.1 - 0.024 14.5 6.7 7.6 6.6 0.1 5.4 5 0 0 5 5 5 0 Antidote-toxin recognition MazE, bacterial antitoxin RlmM_FDX PF18125.1 KFQ94951.1 - 0.35 11.4 2.1 52 4.4 0.0 3.8 4 0 0 4 4 4 0 RlmM ferredoxin-like domain OB_RNB PF08206.11 KFQ94951.1 - 0.41 10.4 9.7 26 4.6 0.1 5.1 5 0 0 5 5 5 0 Ribonuclease B OB domain zf-C4 PF00105.18 KFQ94952.1 - 6.2e-29 100.3 14.4 6.2e-29 100.3 14.4 2.1 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFQ94952.1 - 2e-17 63.4 0.4 7e-17 61.7 0.1 2.0 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor Type_III_YscX PF09474.10 KFQ94952.1 - 0.017 15.4 0.0 0.038 14.3 0.0 1.6 1 0 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) Cys_knot PF00007.22 KFQ94953.1 - 2.6e-30 104.8 14.5 3e-30 104.6 14.5 1.0 1 0 0 1 1 1 1 Cystine-knot domain Pkinase PF00069.25 KFQ94954.1 - 6.6e-62 209.3 0.2 7.6e-62 209.1 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ94954.1 - 1.1e-24 87.2 0.1 1.4e-24 86.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFQ94954.1 - 4.8e-05 23.4 0.2 8.5e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFQ94954.1 - 0.00072 19.0 0.1 0.001 18.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFQ94954.1 - 0.0042 16.4 0.1 0.016 14.5 0.0 1.9 2 0 0 2 2 2 1 Kinase-like DUF3754 PF12576.8 KFQ94954.1 - 0.019 14.9 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) Haspin_kinase PF12330.8 KFQ94954.1 - 0.02 13.8 0.1 0.032 13.2 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KFQ94954.1 - 0.071 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 EPL1 PF10513.9 KFQ94955.1 - 1.3e-37 129.6 0.9 1.2e-35 123.2 0.4 3.0 2 1 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H_2 PF13832.6 KFQ94955.1 - 1.2e-36 125.2 6.1 1.2e-36 125.2 6.1 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFQ94955.1 - 2.3e-25 88.7 4.1 2.3e-25 88.7 4.1 3.4 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.25 KFQ94955.1 - 2.4e-20 72.4 0.2 7.2e-20 70.8 0.2 1.9 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.17 KFQ94955.1 - 2.1e-17 63.3 0.0 7.6e-17 61.5 0.0 2.1 1 0 0 1 1 1 1 PWWP domain PHD_2 PF13831.6 KFQ94955.1 - 3.9e-12 45.5 6.8 3.9e-12 45.5 6.8 2.7 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 KFQ94955.1 - 2.3e-06 27.4 28.6 0.0001 22.1 16.8 2.7 2 0 0 2 2 2 2 PHD-finger Elf-1_N PF12310.8 KFQ94955.1 - 0.061 13.9 0.0 0.2 12.2 0.0 1.9 1 0 0 1 1 1 0 Transcription factor protein N terminal C1_1 PF00130.22 KFQ94955.1 - 1.9 8.4 19.2 0.04 13.8 6.5 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RabGAP-TBC PF00566.18 KFQ94956.1 - 9.4e-53 179.0 2.9 1.3e-52 178.6 2.9 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MIF4G PF02854.19 KFQ94956.1 - 0.059 13.0 0.0 1.4 8.5 0.0 2.4 1 1 0 2 2 2 0 MIF4G domain DUF4864 PF16156.5 KFQ94956.1 - 0.086 13.5 0.0 0.23 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4864) Pkinase PF00069.25 KFQ94957.1 - 7e-50 169.8 0.0 1.1e-49 169.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ94957.1 - 3.1e-12 46.3 0.0 4.7e-12 45.7 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ94957.1 - 2.7e-07 30.2 0.0 3.2e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFQ94957.1 - 7.2e-07 28.8 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFQ94957.1 - 0.0083 14.9 0.0 0.01 14.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFQ94957.1 - 0.032 14.2 0.1 0.055 13.4 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KFQ94957.1 - 0.094 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 KFQ94957.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 KFQ94957.1 - 0.22 10.5 0.0 0.36 9.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RhoGEF PF00621.20 KFQ94958.1 - 7.3e-48 163.2 1.1 1e-47 162.7 1.1 1.2 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 KFQ94958.1 - 1.1e-17 64.0 9.2 2e-17 63.0 9.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 KFQ94958.1 - 5.8e-14 52.5 0.0 7.6e-08 32.8 0.0 2.5 2 0 0 2 2 2 2 PH domain FYVE_2 PF02318.16 KFQ94958.1 - 7.3e-05 23.0 6.4 7.3e-05 23.0 4.7 1.9 2 0 0 2 2 2 1 FYVE-type zinc finger IQ_SEC7_PH PF16453.5 KFQ94958.1 - 0.025 14.6 0.0 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 PH domain PH_13 PF16652.5 KFQ94958.1 - 0.15 11.9 0.0 6.8 6.5 0.0 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain zf-HC5HC2H PF13771.6 KFQ94958.1 - 0.18 12.1 4.8 0.36 11.1 4.8 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain C1_1 PF00130.22 KFQ94958.1 - 0.6 10.0 8.7 0.12 12.3 5.0 1.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Mito_carr PF00153.27 KFQ94959.1 - 7.8e-15 54.6 0.1 1e-08 34.9 0.0 2.7 3 0 0 3 3 3 2 Mitochondrial carrier protein CAP PF00188.26 KFQ94960.1 - 6.6e-21 75.4 0.5 1.2e-20 74.7 0.5 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family FGAR-AT_linker PF18072.1 KFQ94960.1 - 0.097 13.2 0.1 0.41 11.2 0.1 2.0 1 1 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase linker domain MSC PF09402.10 KFQ94960.1 - 0.14 11.6 3.4 0.19 11.2 3.4 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Ras PF00071.22 KFQ94962.1 - 1.9e-48 164.1 0.0 2.3e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ94962.1 - 4.1e-27 94.8 0.0 5.7e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ94962.1 - 4.3e-14 52.3 0.0 5.7e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFQ94962.1 - 4.6e-06 26.3 0.0 0.00069 19.2 0.0 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFQ94962.1 - 5.4e-06 25.9 0.0 6.3e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFQ94962.1 - 9.3e-06 25.2 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFQ94962.1 - 2.2e-05 24.5 0.0 3.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase CENP-M PF11111.8 KFQ94962.1 - 0.011 14.9 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) RsgA_GTPase PF03193.16 KFQ94962.1 - 0.14 12.0 0.0 6.1 6.7 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 KFQ94962.1 - 0.15 12.2 0.0 0.23 11.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain CDI PF02234.19 KFQ94963.1 - 5.5e-21 74.5 3.7 6e-21 74.4 3.7 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor TetR_C_8 PF14278.6 KFQ94963.1 - 0.019 15.0 0.0 0.021 14.9 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region EXS PF03124.14 KFQ94965.1 - 1.1e-106 356.9 24.6 1.5e-106 356.5 24.6 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KFQ94965.1 - 5.7e-21 75.9 15.2 4.5e-14 53.2 5.5 2.3 1 1 1 2 2 2 2 SPX domain DUF4685 PF15737.5 KFQ94966.1 - 1.4e-19 70.7 3.6 5.6e-19 68.8 3.6 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4685) Syntaxin-6_N PF09177.11 KFQ94967.1 - 7.2e-30 103.5 0.6 7.2e-30 103.5 0.6 2.8 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KFQ94967.1 - 1.9e-13 50.2 1.8 4.9e-13 48.9 1.8 1.8 1 0 0 1 1 1 1 SNARE domain Prominin PF05478.11 KFQ94967.1 - 0.012 13.6 4.3 0.048 11.6 4.5 1.7 1 1 1 2 2 2 0 Prominin UPF0184 PF03670.13 KFQ94967.1 - 0.03 14.7 0.4 0.73 10.3 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Use1 PF09753.9 KFQ94967.1 - 0.065 13.0 5.5 0.11 12.2 5.4 1.4 1 1 0 1 1 1 0 Membrane fusion protein Use1 Pox_EPC_I2-L1 PF12575.8 KFQ94967.1 - 0.082 13.1 1.1 0.19 12.0 1.1 1.6 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 FliD_C PF07195.12 KFQ94967.1 - 0.087 12.2 4.0 3.7 6.9 0.0 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus APG17 PF04108.12 KFQ94967.1 - 0.21 10.7 10.5 0.054 12.6 2.0 2.4 1 1 1 2 2 2 0 Autophagy protein Apg17 DUF1664 PF07889.12 KFQ94967.1 - 0.7 9.9 6.5 12 6.0 2.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) EMP24_GP25L PF01105.24 KFQ94967.1 - 2.1 8.3 5.2 0.86 9.5 2.1 2.1 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Exonuc_VII_L PF02601.15 KFQ94967.1 - 2.4 7.7 8.5 4.6 6.7 8.5 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit KxDL PF10241.9 KFQ94967.1 - 2.6 8.4 7.5 2.4 8.5 3.1 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein Ion_trans PF00520.31 KFQ94968.1 - 2e-242 800.1 79.9 2.3e-64 217.0 1.0 4.1 4 0 0 4 4 4 4 Ion transport protein Ca_chan_IQ PF08763.11 KFQ94968.1 - 6.3e-30 103.2 0.3 1.7e-29 101.9 0.3 1.8 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain GPHH PF16905.5 KFQ94968.1 - 1.2e-27 95.4 0.1 6.1e-27 93.2 0.1 2.3 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 KFQ94968.1 - 5.9e-11 41.7 78.0 2.5e-07 29.7 5.7 9.4 7 4 4 11 11 11 6 Polycystin cation channel zf-H2C2_2 PF13465.6 KFQ94970.1 - 3.6e-38 128.3 44.0 5.7e-07 29.7 2.8 7.3 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ94970.1 - 1.7e-29 100.6 41.3 5.1e-05 23.5 3.1 7.1 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ94970.1 - 1.2e-22 78.6 39.8 0.00094 19.8 2.0 7.1 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ94970.1 - 2.2e-12 46.9 13.0 0.12 12.7 0.1 6.9 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zinc_ribbon_9 PF14369.6 KFQ94970.1 - 6.4e-10 39.1 15.5 0.068 13.5 0.4 6.2 5 1 1 6 6 6 3 zinc-ribbon Zn-ribbon_8 PF09723.10 KFQ94970.1 - 2.7e-08 33.8 25.6 0.015 15.4 1.0 5.6 4 1 3 7 7 7 4 Zinc ribbon domain zf-Di19 PF05605.12 KFQ94970.1 - 5.5e-07 29.8 22.7 0.0006 20.1 0.9 4.6 3 2 2 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 KFQ94970.1 - 7.5e-07 28.8 26.6 0.024 14.4 1.1 6.1 7 0 0 7 7 6 3 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFQ94970.1 - 1.8e-06 27.8 40.9 0.032 14.2 0.2 7.6 7 1 0 7 7 7 2 C2H2-type zinc finger zf_UBZ PF18439.1 KFQ94970.1 - 4.8e-05 22.9 20.7 4.1 7.1 0.0 7.1 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 KFQ94970.1 - 0.00039 21.1 16.7 0.37 11.5 0.2 4.8 1 1 3 4 4 4 1 Zinc finger C2H2-type, 3 repeats zf-trcl PF13451.6 KFQ94970.1 - 0.00066 19.5 21.5 0.27 11.2 0.1 6.0 5 1 0 5 5 5 1 Probable zinc-ribbon domain zf-C2HE PF16278.5 KFQ94970.1 - 0.00086 19.7 23.5 0.004 17.6 2.3 4.9 1 1 3 4 4 4 1 C2HE / C2H2 / C2HC zinc-binding finger HypA PF01155.19 KFQ94970.1 - 0.002 18.1 13.5 1.8 8.6 3.2 3.5 1 1 2 3 3 3 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_SprT PF17283.2 KFQ94970.1 - 0.0062 16.4 24.2 0.45 10.5 1.7 5.1 2 2 4 6 6 6 3 SprT-like zinc ribbon domain zf-met PF12874.7 KFQ94970.1 - 0.0071 16.7 16.6 1.1 9.7 0.0 5.7 6 0 0 6 6 5 1 Zinc-finger of C2H2 type FYDLN_acid PF09538.10 KFQ94970.1 - 0.0077 16.9 8.9 10 6.9 1.3 5.2 1 1 4 5 5 5 0 Protein of unknown function (FYDLN_acid) Rad50_zn_hook PF04423.14 KFQ94970.1 - 0.0088 15.9 6.5 2.1 8.3 0.0 4.0 4 0 0 4 4 4 1 Rad50 zinc hook motif C1_1 PF00130.22 KFQ94970.1 - 0.0097 15.8 21.5 0.76 9.7 2.0 5.4 3 2 3 6 6 6 3 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc-ribbons_6 PF07191.12 KFQ94970.1 - 0.023 14.7 18.6 35 4.5 1.1 5.1 1 1 1 2 2 2 0 zinc-ribbons DUF2225 PF09986.9 KFQ94970.1 - 0.028 14.1 11.0 1.1 8.9 0.2 4.0 3 2 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) YacG PF03884.14 KFQ94970.1 - 0.051 13.3 6.7 24 4.8 0.1 4.5 4 0 0 4 4 4 0 DNA gyrase inhibitor YacG Evr1_Alr PF04777.13 KFQ94970.1 - 0.069 13.6 15.3 3.4 8.2 0.3 5.0 1 1 4 5 5 5 0 Erv1 / Alr family C1_4 PF07975.12 KFQ94970.1 - 0.083 13.1 22.2 1.6 9.0 1.1 5.0 1 1 5 6 6 6 0 TFIIH C1-like domain zf-RING_7 PF02591.15 KFQ94970.1 - 0.084 13.1 15.2 13 6.1 0.1 5.7 6 0 0 6 6 5 0 C4-type zinc ribbon domain zinc_ribbon_15 PF17032.5 KFQ94970.1 - 0.088 13.6 17.0 2.1 9.1 0.3 4.0 1 1 3 4 4 4 0 zinc-ribbon family Zn_ribbon_recom PF13408.6 KFQ94970.1 - 0.11 13.1 20.1 1.2 9.7 0.4 5.1 3 1 2 5 5 5 0 Recombinase zinc beta ribbon domain Acetone_carb_G PF08882.11 KFQ94970.1 - 0.17 12.0 0.2 0.17 12.0 0.2 2.6 2 2 1 3 3 3 0 Acetone carboxylase gamma subunit FYVE PF01363.21 KFQ94970.1 - 0.27 11.4 24.9 17 5.6 7.8 5.5 1 1 4 5 5 5 0 FYVE zinc finger DNA_ligase_ZBD PF03119.16 KFQ94970.1 - 0.27 11.3 5.7 27 4.9 0.0 4.1 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain XPA_N PF01286.18 KFQ94970.1 - 0.27 11.3 21.4 20 5.3 0.1 6.6 7 0 0 7 7 7 0 XPA protein N-terminal zf-C2H2_9 PF16293.5 KFQ94970.1 - 0.28 11.1 8.3 8.6 6.3 0.0 4.2 4 2 2 6 6 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 KFQ94970.1 - 0.45 10.9 15.8 8 6.9 0.3 5.2 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) BolA PF01722.18 KFQ94970.1 - 0.51 10.7 6.4 12 6.3 0.1 3.5 2 1 1 3 3 3 0 BolA-like protein zf-AN1 PF01428.16 KFQ94970.1 - 0.55 10.4 31.2 12 6.1 0.1 6.5 5 2 1 6 6 6 0 AN1-like Zinc finger PyrI_C PF02748.15 KFQ94970.1 - 0.63 10.0 0.1 0.63 10.0 0.1 4.2 4 1 1 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF3268 PF11672.8 KFQ94970.1 - 0.84 10.0 12.3 13 6.1 0.4 3.6 1 1 2 4 4 4 0 zinc-finger-containing domain zf-C2HC_2 PF13913.6 KFQ94970.1 - 1.1 9.3 0.1 1.1 9.3 0.1 5.3 7 0 0 7 7 6 0 zinc-finger of a C2HC-type zf-ribbon_3 PF13248.6 KFQ94970.1 - 2 7.9 25.4 2 7.9 0.1 6.1 7 0 0 7 7 6 0 zinc-ribbon domain CpXC PF14353.6 KFQ94970.1 - 3.5 7.7 21.1 22 5.1 0.1 5.9 1 1 5 6 6 6 0 CpXC protein zf-Mss51 PF13824.6 KFQ94970.1 - 3.8 7.7 27.6 15 5.7 0.6 5.7 3 1 1 4 4 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-FPG_IleRS PF06827.14 KFQ94970.1 - 4.8 7.1 17.7 8.8 6.3 0.2 5.6 6 0 0 6 6 5 0 Zinc finger found in FPG and IleRS GAGA PF09237.11 KFQ94970.1 - 5.1 7.0 14.8 13 5.6 0.1 4.6 1 1 5 6 6 6 0 GAGA factor Zn-C2H2_12 PF18112.1 KFQ94970.1 - 5.3 7.6 11.5 14 6.2 0.4 4.5 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain OrfB_Zn_ribbon PF07282.11 KFQ94970.1 - 6 6.9 25.1 16 5.5 0.3 5.5 3 1 3 6 6 6 0 Putative transposase DNA-binding domain ADK_lid PF05191.14 KFQ94970.1 - 7.3 6.7 21.4 0.36 10.8 1.6 4.7 3 2 1 4 4 4 0 Adenylate kinase, active site lid PHD PF00628.29 KFQ94970.1 - 7.7 6.5 23.5 4.2 7.4 2.5 5.4 5 1 1 6 6 6 0 PHD-finger zf_C2H2_ZHX PF18387.1 KFQ94970.1 - 7.9 6.2 15.5 14 5.4 3.1 4.7 3 1 2 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain Gln-synt_C PF00120.24 KFQ94971.1 - 1.2e-17 64.0 0.0 1.5e-12 47.2 0.0 2.2 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KFQ94971.1 - 2.5e-14 52.8 0.0 4.2e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain F-box-like PF12937.7 KFQ94971.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 F-box-like RGS PF00615.19 KFQ94972.1 - 1.2e-09 38.5 0.1 5.5e-05 23.4 0.1 3.5 3 1 0 3 3 3 2 Regulator of G protein signaling domain Ank_2 PF12796.7 KFQ94974.1 - 3.7e-41 139.6 7.6 5.1e-14 52.6 0.0 5.2 3 2 2 5 5 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ94974.1 - 3.2e-40 136.0 0.8 5.1e-09 36.5 0.1 6.9 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFQ94974.1 - 7e-32 109.1 5.3 2.8e-06 27.5 0.0 6.4 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ94974.1 - 8e-32 105.7 1.8 0.0094 16.4 0.0 8.9 9 0 0 9 9 8 7 Ankyrin repeat Ank PF00023.30 KFQ94974.1 - 6.4e-30 102.3 6.5 0.00025 21.3 0.0 8.6 7 1 1 8 8 8 6 Ankyrin repeat Pkinase PF00069.25 KFQ94974.1 - 3.9e-12 46.1 0.0 1.3e-11 44.4 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain Ribonuc_2-5A PF06479.12 KFQ94974.1 - 4.7e-12 46.2 0.6 2.9e-11 43.6 0.3 2.3 2 0 0 2 2 2 1 Ribonuclease 2-5A Kdo PF06293.14 KFQ94974.1 - 5e-09 35.8 1.2 1.2e-07 31.3 0.0 2.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KFQ94974.1 - 4.8e-05 22.8 0.0 9.7e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFQ94974.1 - 0.03 14.2 0.1 0.069 13.1 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFQ94974.1 - 0.083 11.8 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 KFQ94974.1 - 0.087 12.4 0.1 0.34 10.5 0.1 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF2524 PF10732.9 KFQ94974.1 - 0.34 11.2 1.3 19 5.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) RGS PF00615.19 KFQ94975.1 - 9.4e-37 125.9 3.6 1.2e-36 125.6 3.6 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS PF00615.19 KFQ94976.1 - 3.4e-38 130.5 2.3 4.7e-38 130.1 2.3 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain DNA_gyraseB_C PF00986.21 KFQ94976.1 - 0.034 14.3 0.0 7.5 6.8 0.0 2.3 2 0 0 2 2 2 0 DNA gyrase B subunit, carboxyl terminus Arteri_nsp7a PF16749.5 KFQ94976.1 - 0.044 14.0 0.1 0.058 13.6 0.1 1.2 1 0 0 1 1 1 0 Arterivirus nonstructural protein 7 alpha tRNA-synt_2 PF00152.20 KFQ94977.1 - 1.1e-95 320.3 0.0 1.4e-95 320.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GAD PF02938.14 KFQ94977.1 - 3e-14 53.0 0.0 5.9e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 GAD domain tRNA_anti-codon PF01336.25 KFQ94977.1 - 1.3e-07 31.4 0.0 2.5e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain CENP-L PF13092.6 KFQ94978.1 - 2.3e-32 112.5 0.1 3.3e-32 112.0 0.1 1.2 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Kelch_1 PF01344.25 KFQ94979.1 - 3e-92 302.0 20.9 3.5e-17 61.7 0.5 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFQ94979.1 - 1.1e-53 177.8 7.3 1.9e-09 37.5 0.0 6.4 2 2 4 6 6 6 6 Kelch motif BACK PF07707.15 KFQ94979.1 - 2.4e-38 130.4 0.5 4.3e-38 129.6 0.1 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 KFQ94979.1 - 1.2e-35 121.2 7.1 1.5e-05 24.9 0.0 6.2 2 2 4 6 6 6 6 Galactose oxidase, central domain BTB PF00651.31 KFQ94979.1 - 9.2e-33 112.8 0.7 1.5e-32 112.1 0.3 1.6 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 KFQ94979.1 - 7.8e-32 108.1 6.4 1.2e-06 28.2 0.2 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KFQ94979.1 - 1.1e-30 105.2 16.2 9.3e-06 25.8 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 KFQ94979.1 - 7.9e-06 25.7 8.6 1.9 8.5 0.1 5.9 6 0 0 6 6 6 3 Kelch motif XPA_C PF05181.12 KFQ94979.1 - 0.032 14.2 0.4 5.5 7.0 0.0 3.3 4 0 0 4 4 4 0 XPA protein C-terminus Glu_cyclase_2 PF05096.12 KFQ94979.1 - 0.074 12.5 0.0 29 4.0 0.0 2.7 1 1 0 3 3 3 0 Glutamine cyclotransferase PQQ_3 PF13570.6 KFQ94979.1 - 5 7.8 16.7 1.1 9.9 0.5 4.8 5 0 0 5 5 5 0 PQQ-like domain PRK PF00485.18 KFQ94980.1 - 1e-52 178.8 0.2 1.2e-52 178.6 0.2 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CoaE PF01121.20 KFQ94980.1 - 1.8e-06 27.7 0.4 3.8e-06 26.7 0.4 1.5 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KFQ94980.1 - 0.00017 22.1 0.1 0.00049 20.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFQ94980.1 - 0.0018 17.6 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Cytidylate_kin PF02224.18 KFQ94980.1 - 0.042 13.6 1.4 0.87 9.3 0.2 2.3 2 1 0 2 2 2 0 Cytidylate kinase KTI12 PF08433.10 KFQ94980.1 - 0.086 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_17 PF13207.6 KFQ94980.1 - 0.16 12.4 4.8 1.5 9.3 4.8 2.2 1 1 0 1 1 1 0 AAA domain DUF826 PF05696.11 KFQ94980.1 - 0.16 12.1 0.7 7.8 6.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF826) EMC3_TMCO1 PF01956.16 KFQ94981.1 - 3.6e-43 147.3 1.3 4.2e-43 147.0 1.3 1.0 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like TRAM1 PF08390.11 KFQ94981.1 - 0.0017 18.0 0.5 0.0063 16.1 0.0 2.0 2 0 0 2 2 2 1 TRAM1-like protein Vpu PF00558.19 KFQ94981.1 - 0.0072 16.1 1.2 0.013 15.2 1.2 1.5 1 1 0 1 1 1 1 Vpu protein DUF4199 PF13858.6 KFQ94981.1 - 0.011 16.1 0.1 0.022 15.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF2368 PF10166.9 KFQ94981.1 - 0.018 14.7 0.1 0.029 14.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Connexin PF00029.19 KFQ94981.1 - 0.052 13.3 0.2 0.076 12.8 0.2 1.2 1 0 0 1 1 1 0 Connexin DUF4257 PF14074.6 KFQ94981.1 - 0.059 13.6 0.6 0.31 11.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4257) DivIC PF04977.15 KFQ94981.1 - 0.11 12.3 0.5 0.11 12.3 0.5 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF3899 PF13038.6 KFQ94981.1 - 0.12 12.9 0.8 1.4 9.5 0.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3899) Nucleoside_tran PF01733.18 KFQ94981.1 - 0.15 11.4 3.0 0.13 11.6 1.2 1.7 1 1 1 2 2 2 0 Nucleoside transporter DUF1090 PF06476.12 KFQ94981.1 - 0.87 9.7 12.9 1.5 9.0 12.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) XhlA PF10779.9 KFQ94981.1 - 1.1 9.5 6.5 6.1 7.1 6.3 2.1 1 1 1 2 2 2 0 Haemolysin XhlA Atg14 PF10186.9 KFQ94981.1 - 1.8 7.5 6.6 2.6 7.0 6.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SieB PF14163.6 KFQ94981.1 - 4.9 6.6 7.2 16 5.0 5.1 2.5 2 1 0 2 2 2 0 Super-infection exclusion protein B Aldedh PF00171.22 KFQ94982.1 - 8.5e-169 561.9 0.0 9.5e-169 561.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MAPEG PF01124.18 KFQ94983.1 - 8.3e-22 77.5 0.7 1e-21 77.2 0.7 1.1 1 0 0 1 1 1 1 MAPEG family LRR_8 PF13855.6 KFQ94984.1 - 1.1e-22 79.6 18.1 3.7e-11 42.6 1.5 3.3 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFQ94984.1 - 5.6e-09 36.1 7.6 0.0008 19.7 0.3 3.5 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRRNT PF01462.18 KFQ94984.1 - 9.8e-05 21.9 1.1 9.8e-05 21.9 1.1 2.3 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.6 KFQ94984.1 - 0.0028 17.6 0.1 0.0045 17.0 0.1 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFQ94984.1 - 0.12 13.0 8.6 0.31 11.7 0.1 4.9 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 KFQ94984.1 - 0.18 12.0 12.4 1.7 8.9 0.0 4.9 6 0 0 6 6 6 0 Leucine Rich repeat Nuf2 PF03800.14 KFQ94985.1 - 8.1e-36 123.2 0.1 8.1e-36 123.2 0.1 2.7 3 0 0 3 3 3 1 Nuf2 family Filament PF00038.21 KFQ94985.1 - 0.011 15.3 48.7 0.02 14.5 17.6 3.8 1 1 3 4 4 4 0 Intermediate filament protein HMMR_N PF15905.5 KFQ94985.1 - 0.059 12.8 57.5 0.1 12.0 20.6 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal SAVED PF18145.1 KFQ94985.1 - 0.15 11.9 3.3 1.6 8.5 0.1 3.0 2 1 1 3 3 3 0 SMODS-associated and fused to various effectors sensor domain Atg14 PF10186.9 KFQ94985.1 - 0.36 9.9 45.8 0.33 10.0 17.7 3.0 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 KFQ94985.1 - 0.7 10.1 47.8 0.031 14.5 26.4 3.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF5644 PF18712.1 KFQ94985.1 - 0.91 9.6 6.2 0.2 11.7 0.3 2.9 4 0 0 4 4 4 0 Family of unknown function (DUF5644) DUF3584 PF12128.8 KFQ94985.1 - 1.6 6.1 47.2 1.2 6.6 29.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) ApoLp-III PF07464.11 KFQ94985.1 - 4.2 7.4 33.9 0.9 9.6 8.2 3.8 1 1 3 4 4 4 0 Apolipophorin-III precursor (apoLp-III) LMBR1 PF04791.16 KFQ94985.1 - 6 5.6 34.4 2.1 7.2 16.6 2.1 1 1 1 2 2 2 0 LMBR1-like membrane protein PBC PF03792.13 KFQ94986.1 - 3.1e-67 226.0 0.3 5.1e-67 225.3 0.0 1.5 2 0 0 2 2 2 1 PBC domain Homeodomain PF00046.29 KFQ94986.1 - 8.8e-20 70.3 0.9 2.1e-19 69.1 0.9 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ94986.1 - 4.6e-16 58.4 0.0 1.1e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 KFQ94986.1 - 0.0021 17.9 0.0 0.0052 16.6 0.0 1.6 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 KFQ94986.1 - 0.0088 16.1 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix Sec15 PF04091.12 KFQ94986.1 - 0.01 15.3 0.6 0.015 14.7 0.6 1.3 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like LZ3wCH PF18517.1 KFQ94986.1 - 0.15 12.1 0.0 1 9.5 0.0 2.3 2 0 0 2 2 2 0 Leucine zipper with capping helix domain NUC130_3NT PF08158.12 KFQ94986.1 - 0.46 10.8 1.6 27 5.2 0.1 3.0 3 1 0 3 3 3 0 NUC130/3NT domain LIM PF00412.22 KFQ94987.1 - 4e-29 100.6 22.4 9.2e-15 54.6 8.1 2.3 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 KFQ94987.1 - 4.6e-18 64.8 2.5 8.2e-18 64.0 2.5 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ94987.1 - 0.00011 22.1 0.0 0.00025 20.9 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Nuc_recep-AF1 PF11825.8 KFQ94988.1 - 9.8e-44 148.0 14.7 1.9e-43 147.1 14.7 1.5 1 0 0 1 1 1 1 Nuclear/hormone receptor activator site AF-1 Hormone_recep PF00104.30 KFQ94988.1 - 2.1e-38 132.0 0.0 4.4e-38 130.9 0.0 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFQ94988.1 - 4.7e-32 110.3 15.8 7.9e-32 109.5 15.8 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Sushi PF00084.20 KFQ94989.1 - 4.7e-53 177.6 65.1 6.3e-10 39.5 4.0 7.2 7 0 0 7 7 7 6 Sushi repeat (SCR repeat) Lectin_C PF00059.21 KFQ94989.1 - 3.7e-22 79.1 5.1 3.7e-22 79.1 5.1 2.9 4 0 0 4 4 4 1 Lectin C-type domain EGF_2 PF07974.13 KFQ94989.1 - 6.1e-05 23.3 12.3 0.00023 21.5 9.4 3.8 2 0 0 2 2 2 1 EGF-like domain EGF PF00008.27 KFQ94989.1 - 0.0017 18.7 11.3 0.0017 18.7 11.3 4.7 7 0 0 7 7 7 1 EGF-like domain hEGF PF12661.7 KFQ94989.1 - 0.0025 18.4 5.9 0.0025 18.4 5.9 5.0 5 0 0 5 5 5 1 Human growth factor-like EGF EGF_3 PF12947.7 KFQ94989.1 - 0.022 14.9 5.0 0.022 14.9 5.0 5.7 6 0 0 6 6 6 0 EGF domain Ocnus PF05005.15 KFQ94990.1 - 6.3e-24 84.2 0.3 6.9e-24 84.0 0.3 1.0 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) Methyltransf_16 PF10294.9 KFQ94991.1 - 4.5e-12 46.0 0.1 0.00011 22.0 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 KFQ94991.1 - 6.9e-06 26.0 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFQ94991.1 - 2.7e-05 23.8 0.0 4.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KFQ94991.1 - 4.7e-05 22.9 0.1 6.9e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KFQ94991.1 - 0.00011 22.1 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KFQ94991.1 - 0.012 16.3 0.1 0.11 13.3 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KFQ94991.1 - 0.015 14.9 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 KFQ94991.1 - 0.027 15.2 0.0 0.099 13.4 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KFQ94991.1 - 0.079 12.1 0.0 0.16 11.2 0.0 1.4 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family DUF4487 PF14868.6 KFQ94992.1 - 1.2e-189 631.7 27.1 1.2e-189 631.7 27.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4487) Pkinase PF00069.25 KFQ94993.1 - 3.7e-06 26.5 0.0 6.9e-05 22.3 0.0 2.4 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ94993.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase KAP PF05804.12 KFQ94994.1 - 0 1368.3 24.8 0 1368.2 24.8 1.0 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Arm PF00514.23 KFQ94994.1 - 3.6e-08 33.2 9.4 0.21 11.7 0.1 7.2 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat RICTOR_M PF14666.6 KFQ94994.1 - 0.025 14.3 0.3 0.13 12.1 0.0 2.4 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain FPL PF09758.9 KFQ94994.1 - 0.036 14.1 11.9 0.067 13.2 3.9 3.8 2 1 0 3 3 3 0 Uncharacterised conserved protein Herpes_UL33 PF03581.13 KFQ94994.1 - 0.038 14.3 0.1 0.47 10.9 0.1 2.5 2 0 0 2 2 2 0 Herpesvirus UL33-like protein HEAT PF02985.22 KFQ94994.1 - 0.13 12.6 1.1 7.5 7.1 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat V-ATPase_H_C PF11698.8 KFQ94994.1 - 4 7.6 9.8 3.3 7.8 0.2 4.1 4 0 0 4 4 4 0 V-ATPase subunit H Methyltransf_PK PF05891.12 KFQ94995.1 - 6e-69 231.9 0.0 8.1e-69 231.5 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KFQ94995.1 - 1.5e-06 28.8 0.0 2.5e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFQ94995.1 - 2.6e-05 24.8 0.0 4.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFQ94995.1 - 0.0005 20.8 0.0 0.00083 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KFQ94995.1 - 0.0024 17.2 0.0 0.0029 16.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Transcrip_act PF04949.13 KFQ94996.1 - 8.3e-08 32.3 18.9 2.9e-07 30.5 18.8 1.9 1 1 0 1 1 1 1 Transcriptional activator DUF1828 PF08861.10 KFQ94996.1 - 4.8 7.5 8.7 0.45 10.8 1.3 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF1828 Homeodomain PF00046.29 KFQ94997.1 - 3.3e-23 81.3 6.4 6.3e-23 80.4 6.4 1.5 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 KFQ94997.1 - 4.6e-08 32.6 0.1 9.1e-08 31.7 0.1 1.5 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 KFQ94997.1 - 0.00052 19.9 0.2 0.0014 18.4 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain FMO-like PF00743.19 KFQ94998.1 - 1.1e-235 783.1 0.0 1.3e-235 782.9 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFQ94998.1 - 1.6e-15 57.2 0.0 7.3e-12 45.1 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFQ94998.1 - 1.8e-11 43.9 0.0 1.2e-09 37.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFQ94998.1 - 4.9e-07 29.2 0.0 1.5e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KFQ94998.1 - 0.0001 22.5 0.0 0.00028 21.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KFQ94998.1 - 0.00032 20.7 0.0 0.002 18.2 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KFQ94998.1 - 0.0005 19.8 0.1 0.051 13.2 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFQ94998.1 - 0.0072 16.9 0.2 2.4 8.8 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KFQ94998.1 - 0.23 10.8 0.0 1 8.7 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OLF PF02191.16 KFQ94999.1 - 3.2e-82 275.8 0.0 3.6e-82 275.7 0.0 1.0 1 0 0 1 1 1 1 Olfactomedin-like domain Synaptobrevin PF00957.21 KFQ95000.1 - 1.9e-34 117.3 3.2 2.2e-34 117.1 3.2 1.0 1 0 0 1 1 1 1 Synaptobrevin MCU PF04678.13 KFQ95000.1 - 0.001 19.2 0.0 0.0013 18.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Fzo_mitofusin PF04799.13 KFQ95000.1 - 0.0054 16.3 0.7 0.0075 15.8 0.7 1.2 1 0 0 1 1 1 1 fzo-like conserved region DUF1035 PF06281.12 KFQ95000.1 - 0.016 15.2 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) RIFIN PF02009.16 KFQ95000.1 - 0.03 14.2 0.1 0.036 14.0 0.1 1.1 1 0 0 1 1 1 0 Rifin NPV_P10 PF05531.12 KFQ95000.1 - 0.033 14.6 0.3 0.051 14.0 0.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Ferlin_C PF16165.5 KFQ95000.1 - 0.053 13.5 0.0 0.061 13.3 0.0 1.2 1 0 0 1 1 1 0 Ferlin C-terminus DUF5345 PF17280.2 KFQ95000.1 - 0.056 13.4 0.2 0.086 12.8 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5345) UPF0258 PF06789.12 KFQ95000.1 - 0.09 12.9 0.7 0.13 12.4 0.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) DUF1664 PF07889.12 KFQ95000.1 - 3.1 7.9 8.4 0.94 9.5 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 KFQ95000.1 - 4.1 7.7 8.1 0.4 11.0 0.2 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) GP41 PF00517.17 KFQ95000.1 - 4.7 7.1 10.2 0.22 11.4 0.5 2.0 1 1 1 2 2 2 0 Retroviral envelope protein Ham1p_like PF01725.16 KFQ95001.1 - 4.2e-48 163.7 0.0 4.7e-48 163.6 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Methyltransf_25 PF13649.6 KFQ95002.1 - 2.8e-20 72.8 0.1 1.5e-12 48.1 0.1 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 KFQ95002.1 - 7.7e-20 71.2 0.0 3.4e-13 49.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KFQ95002.1 - 1.6e-18 67.1 0.1 3.2e-14 53.3 0.0 3.2 2 1 0 2 2 2 2 Methyltransferase domain Spermine_synth PF01564.17 KFQ95002.1 - 4.4e-10 39.3 0.1 3.4e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 Spermine/spermidine synthase domain MTS PF05175.14 KFQ95002.1 - 5.1e-06 26.1 0.0 0.0047 16.5 0.0 2.5 3 0 0 3 3 3 2 Methyltransferase small domain Methyltransf_12 PF08242.12 KFQ95002.1 - 5.3e-06 27.1 0.0 0.01 16.5 0.0 2.8 2 1 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 KFQ95002.1 - 4.5e-05 22.9 0.1 0.00035 20.0 0.1 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KFQ95002.1 - 8.3e-05 22.5 0.0 0.1 12.4 0.0 3.1 2 1 0 2 2 2 2 Methyltransferase domain DUF3531 PF12049.8 KFQ95002.1 - 0.19 11.6 0.1 0.35 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3531) Dynamin_M PF01031.20 KFQ95003.1 - 5.8e-103 344.0 3.8 5.8e-103 344.0 3.8 2.1 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KFQ95003.1 - 7.5e-43 146.5 0.0 2.5e-42 144.8 0.0 2.0 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KFQ95003.1 - 7.1e-28 96.6 4.8 7.1e-28 96.6 4.8 2.9 3 0 0 3 3 3 1 Dynamin GTPase effector domain PH PF00169.29 KFQ95003.1 - 1.4e-13 51.2 0.7 3.4e-13 50.0 0.7 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFQ95003.1 - 0.1 13.0 1.5 0.62 10.5 1.5 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain DASH_Duo1 PF08651.10 KFQ95003.1 - 0.1 12.4 0.1 9.3 6.1 0.0 2.8 2 0 0 2 2 2 0 DASH complex subunit Duo1 GPI2 PF06432.11 KFQ95004.1 - 7.8e-73 245.3 7.2 8.8e-73 245.2 7.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Sad1_UNC PF07738.13 KFQ95005.1 - 3.8e-37 127.3 0.0 9.2e-37 126.0 0.0 1.7 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal dNK PF01712.19 KFQ95005.1 - 0.015 15.2 0.7 0.032 14.1 0.7 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase MbeD_MobD PF04899.12 KFQ95005.1 - 0.035 14.2 6.5 0.12 12.5 6.5 1.9 1 0 0 1 1 1 0 MbeD/MobD like Tweety PF04906.13 KFQ95005.1 - 0.073 11.7 4.8 0.12 11.0 4.8 1.2 1 0 0 1 1 1 0 Tweety TraH_2 PF06871.11 KFQ95005.1 - 0.093 12.4 0.3 0.27 10.9 0.3 1.7 1 0 0 1 1 1 0 TraH_2 DUF4658 PF15555.6 KFQ95005.1 - 0.17 12.0 0.7 0.46 10.6 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) Telomere_reg-2 PF10193.9 KFQ95005.1 - 0.46 10.9 3.1 2 8.9 3.2 2.0 2 0 0 2 2 2 0 Telomere length regulation protein SlyX PF04102.12 KFQ95005.1 - 1.2 9.8 11.9 3.3 8.4 3.8 3.0 1 1 1 2 2 2 0 SlyX DUF3169 PF11368.8 KFQ95005.1 - 2.3 7.6 4.5 2.6 7.5 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) OmpH PF03938.14 KFQ95005.1 - 4.8 7.5 15.4 1.8 8.9 8.1 3.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Baculo_PEP_C PF04513.12 KFQ95005.1 - 6.2 6.9 13.7 0.1 12.6 6.2 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TNF PF00229.18 KFQ95006.1 - 1.4e-31 109.1 0.2 2.3e-31 108.4 0.2 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Ni_hydr_CYTB PF01292.20 KFQ95006.1 - 0.091 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 GAPT PF11770.8 KFQ95006.1 - 0.48 10.3 1.6 9.7 6.0 1.6 2.2 1 1 0 1 1 1 0 GRB2-binding adapter (GAPT) DUF4488 PF14869.6 KFQ95007.1 - 0.084 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4488) SAGA-Tad1 PF12767.7 KFQ95008.1 - 2.3e-27 96.2 0.5 6.3e-15 55.6 0.1 2.3 1 1 1 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.14 KFQ95008.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family RFC1 PF08519.12 KFQ95009.1 - 0.05 13.8 0.0 0.061 13.5 0.0 1.2 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain PAP2 PF01569.21 KFQ95010.1 - 2.1e-19 69.6 4.6 3.5e-19 68.9 4.6 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KFQ95010.1 - 9.1e-07 28.7 10.9 3.6e-06 26.8 10.9 1.9 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KFQ95010.1 - 0.00097 19.6 3.1 0.00097 19.6 3.1 2.1 1 1 1 2 2 2 1 PAP2 superfamily C-terminal FMO-like PF00743.19 KFQ95011.1 - 2.8e-255 847.7 0.0 3.2e-255 847.6 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFQ95011.1 - 1e-18 67.7 0.0 9.5e-15 54.6 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFQ95011.1 - 4.9e-14 52.3 0.0 1.2e-11 44.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFQ95011.1 - 5.9e-10 38.8 0.6 3.3e-07 29.8 0.0 3.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KFQ95011.1 - 4.5e-06 26.7 0.2 0.15 12.1 0.1 4.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KFQ95011.1 - 1.7e-05 24.9 0.0 8.3e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFQ95011.1 - 2.3e-05 23.7 0.1 0.15 11.3 0.0 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.24 KFQ95011.1 - 5e-05 23.1 2.5 0.036 13.6 0.1 3.1 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFQ95011.1 - 0.00026 21.5 0.6 0.021 15.3 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFQ95011.1 - 0.0014 17.4 0.8 0.25 10.0 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.22 KFQ95011.1 - 0.035 13.2 0.0 1.9 7.5 0.0 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A IlvN PF07991.12 KFQ95011.1 - 0.05 13.2 0.0 2.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_binding_2 PF00890.24 KFQ95011.1 - 0.052 12.6 0.5 6.2 5.8 0.1 2.4 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 KFQ95011.1 - 0.059 12.7 0.3 0.11 11.8 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KFQ95011.1 - 0.11 12.9 0.3 5.4 7.5 0.1 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding AMPK1_CBM PF16561.5 KFQ95012.1 - 3.8e-36 123.2 0.2 6.3e-36 122.5 0.2 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KFQ95012.1 - 7.9e-28 96.5 2.9 1.5e-27 95.6 2.9 1.5 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 KFQ95012.1 - 0.0026 18.1 0.0 0.0052 17.1 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Olduvai PF06758.13 KFQ95013.1 - 7.2e-06 26.2 6.8 1.7e-05 25.0 6.8 1.6 1 0 0 1 1 1 1 Olduvai domain Prok-JAB PF14464.6 KFQ95014.1 - 0.012 15.4 0.1 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic homologs of the JAB domain DUF4164 PF13747.6 KFQ95014.1 - 0.12 12.6 9.3 0.19 12.0 1.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) SMYLE_N PF18615.1 KFQ95015.1 - 1.5e-181 604.2 2.9 1.5e-181 604.2 2.9 4.1 2 1 2 4 4 4 2 Short myomegalin-like EB1 binding proteins, N-terminal domain zf-AD PF07776.15 KFQ95015.1 - 0.0018 18.4 2.0 0.0018 18.4 2.0 3.8 3 1 1 4 4 4 1 Zinc-finger associated domain (zf-AD) Cnd1 PF12717.7 KFQ95015.1 - 0.0063 16.6 1.6 0.0063 16.6 1.6 3.3 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 2-Hacid_dh_C PF02826.19 KFQ95016.1 - 3.6e-60 202.4 0.0 6.2e-60 201.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFQ95016.1 - 1.5e-31 108.8 0.0 2.6e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain HMG_CoA_synt_C PF08540.10 KFQ95017.1 - 1.3e-115 385.9 0.0 1.6e-115 385.6 0.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFQ95017.1 - 3.5e-100 333.1 0.2 4.5e-100 332.7 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Phage_holin_7_1 PF16081.5 KFQ95017.1 - 0.015 15.4 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Abhydrolase_1 PF00561.20 KFQ95017.1 - 0.038 13.6 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold ACP_syn_III PF08545.10 KFQ95017.1 - 0.046 13.6 0.3 0.1 12.5 0.3 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Lectin_C PF00059.21 KFQ95018.1 - 2.7e-15 57.0 2.1 3.2e-15 56.8 2.1 1.1 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 KFQ95018.1 - 0.16 11.6 0.5 0.25 11.0 0.5 1.6 1 1 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Ank_2 PF12796.7 KFQ95020.1 - 4.8e-34 116.8 15.1 1.1e-12 48.4 1.2 4.2 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 KFQ95020.1 - 3.1e-30 103.3 11.3 5.6e-07 29.7 0.0 6.8 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KFQ95020.1 - 1.1e-26 92.6 11.6 1.2e-09 38.2 0.4 5.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ95020.1 - 8.9e-21 71.8 3.8 0.0058 17.1 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 KFQ95020.1 - 1.6e-19 69.9 3.0 3.9e-06 27.3 0.3 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) EGF PF00008.27 KFQ95021.1 - 5.4e-110 359.1 209.8 3.5e-10 40.0 6.5 14.4 14 0 0 14 14 14 14 EGF-like domain hEGF PF12661.7 KFQ95021.1 - 6.2e-81 264.6 181.5 1.9e-07 31.5 3.8 16.2 15 0 0 15 15 15 14 Human growth factor-like EGF EGF_CA PF07645.15 KFQ95021.1 - 5.5e-50 167.3 203.8 8.4e-09 35.5 4.1 14.2 8 5 6 14 14 14 11 Calcium-binding EGF domain EGF_2 PF07974.13 KFQ95021.1 - 4.3e-25 87.8 221.2 0.0042 17.4 4.3 14.3 13 1 1 14 14 14 13 EGF-like domain EGF_3 PF12947.7 KFQ95021.1 - 2.4e-20 72.4 186.7 1.4e-05 25.1 3.1 15.8 11 4 3 14 14 14 11 EGF domain FXa_inhibition PF14670.6 KFQ95021.1 - 6.4e-11 42.3 184.8 0.088 13.1 4.5 14.8 4 3 10 14 14 14 8 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFQ95021.1 - 4.8e-08 32.8 186.4 0.0011 18.9 3.4 17.2 16 3 0 16 16 16 11 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 KFQ95021.1 - 0.007 16.4 5.9 0.007 16.4 5.9 14.4 13 1 1 14 14 14 7 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.11 KFQ95021.1 - 0.01 16.1 14.0 0.024 14.9 2.0 14.4 11 2 3 14 14 14 0 Pvs28 EGF domain Laminin_EGF PF00053.24 KFQ95021.1 - 0.043 14.0 190.1 2.1 8.5 7.7 14.3 3 2 11 14 14 14 0 Laminin EGF domain Longin PF13774.6 KFQ95022.1 - 1.9e-23 82.3 0.1 2.2e-23 82.1 0.1 1.1 1 0 0 1 1 1 1 Regulated-SNARE-like domain Pacs-1 PF10254.9 KFQ95023.1 - 1.1e-204 680.1 0.5 1.1e-204 680.1 0.5 1.6 2 0 0 2 2 2 1 PACS-1 cytosolic sorting protein LIM PF00412.22 KFQ95024.1 - 7.3e-25 87.0 14.8 2.3e-14 53.4 4.0 2.1 2 0 0 2 2 2 2 LIM domain NinD PF17466.2 KFQ95024.1 - 0.0098 16.0 13.8 0.22 11.6 0.1 3.4 2 1 1 3 3 3 2 Family of unknown function zf-CCHC_5 PF14787.6 KFQ95024.1 - 0.013 15.2 0.0 0.013 15.2 0.0 3.6 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger YacG PF03884.14 KFQ95024.1 - 0.018 14.8 8.4 3.5 7.4 0.5 3.5 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG Metallothio_Pro PF02069.16 KFQ95024.1 - 0.034 14.4 6.2 2.7 8.3 0.8 2.6 2 0 0 2 2 2 0 Prokaryotic metallothionein Ribosomal_L37e PF01907.19 KFQ95024.1 - 0.039 14.1 11.8 2 8.6 0.2 3.4 2 1 1 3 3 3 0 Ribosomal protein L37e Pea-VEAacid PF08111.11 KFQ95024.1 - 0.082 13.2 2.6 15 6.2 0.2 2.7 2 0 0 2 2 2 0 Pea-VEAacid family Integrase_H2C2 PF17921.1 KFQ95024.1 - 1.4 9.0 6.7 1.3 9.2 0.2 2.5 2 1 0 2 2 2 0 Integrase zinc binding domain Zn_Tnp_IS1595 PF12760.7 KFQ95024.1 - 1.7 8.6 11.9 0.2 11.6 4.2 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_12 PF11331.8 KFQ95024.1 - 1.8 8.5 7.3 2 8.3 2.0 2.4 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf_UBZ PF18439.1 KFQ95024.1 - 3.9 7.2 25.9 0.65 9.6 1.1 4.4 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger Mut7-C PF01927.16 KFQ95024.1 - 4.7 7.3 6.8 14 5.7 1.5 2.4 2 1 0 2 2 2 0 Mut7-C RNAse domain LIM PF00412.22 KFQ95025.1 - 2.7e-13 49.9 2.3 2.9e-13 49.8 2.3 1.1 1 0 0 1 1 1 1 LIM domain zf_UBZ PF18439.1 KFQ95025.1 - 3.9 7.2 7.4 0.35 10.5 1.1 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF4509 PF14970.6 KFQ95026.1 - 2.7e-58 197.0 0.3 3e-58 196.9 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4509) CECR6_TMEM121 PF14997.6 KFQ95027.1 - 4.4e-60 202.9 11.5 8.1e-60 202.0 11.5 1.4 1 0 0 1 1 1 1 CECR6/TMEM121 family DUF5083 PF16890.5 KFQ95027.1 - 9.5e-05 22.2 1.4 9.5e-05 22.2 1.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5083) PID PF00640.23 KFQ95028.1 - 7.9e-24 84.3 1.9 7.9e-24 84.3 1.9 2.0 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) FAM194 PF14977.6 KFQ95028.1 - 0.73 9.1 4.0 0.24 10.7 0.4 2.0 2 1 1 3 3 3 0 FAM194 protein Phage_GPO PF05929.11 KFQ95028.1 - 0.75 9.4 6.9 0.13 11.9 2.9 1.7 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase SIN1_PH PF16979.5 KFQ95028.1 - 2 8.7 5.9 0.68 10.2 3.2 1.6 2 0 0 2 2 2 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology PID_2 PF14719.6 KFQ95028.1 - 2.1 8.2 5.6 0.19 11.6 0.3 1.9 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) Spt46 PF17734.1 KFQ95029.1 - 2.1e-42 145.5 2.6 2.6e-42 145.2 2.6 1.0 1 0 0 1 1 1 1 Spermatogenesis-associated protein 46 zf-C2H2_4 PF13894.6 KFQ95029.1 - 0.94 10.5 4.3 0.85 10.6 2.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4628 PF15429.6 KFQ95030.1 - 1.7e-43 149.3 1.5 1.8e-43 149.2 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4628) Pkinase PF00069.25 KFQ95031.1 - 2.1e-33 115.8 0.0 2.6e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ95031.1 - 5.2e-17 62.0 0.1 7.2e-17 61.5 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RRM_1 PF00076.22 KFQ95031.1 - 3.7e-08 33.1 0.0 7.1e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinase-like PF14531.6 KFQ95031.1 - 4.5e-08 32.8 0.0 6.1e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFQ95031.1 - 0.00048 19.5 0.1 0.00076 18.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFQ95031.1 - 0.001 19.0 0.1 0.0017 18.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFQ95031.1 - 0.0026 17.4 0.0 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KFQ95031.1 - 0.068 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase UDPGP PF01704.18 KFQ95032.1 - 6.7e-62 209.5 0.0 8.4e-62 209.1 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase F5_F8_type_C PF00754.25 KFQ95033.1 - 4.7e-14 52.6 0.0 5.2e-14 52.5 0.0 1.0 1 0 0 1 1 1 1 F5/8 type C domain Pkinase_Tyr PF07714.17 KFQ95034.1 - 8.4e-85 284.2 0.0 1.1e-84 283.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ95034.1 - 2.6e-43 148.3 0.0 1.9e-41 142.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain F5_F8_type_C PF00754.25 KFQ95034.1 - 0.00032 20.8 0.0 0.0048 17.0 0.0 2.3 2 0 0 2 2 2 1 F5/8 type C domain Haspin_kinase PF12330.8 KFQ95034.1 - 0.018 14.0 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Shisa PF13908.6 KFQ95034.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4834 PF16118.5 KFQ95034.1 - 0.16 12.9 0.0 0.31 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) adh_short PF00106.25 KFQ95035.1 - 1.3e-13 50.9 0.0 1.9e-11 43.8 0.0 3.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFQ95035.1 - 1e-08 35.1 0.0 0.003 17.1 0.0 2.5 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFQ95035.1 - 0.091 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 KR domain OLF PF02191.16 KFQ95036.1 - 1.6e-85 286.7 11.1 2.1e-85 286.2 11.1 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain Noelin-1 PF12308.8 KFQ95036.1 - 0.0014 18.6 0.3 0.012 15.6 0.0 2.3 2 0 0 2 2 2 1 Neurogenesis glycoprotein bZIP_1 PF00170.21 KFQ95037.1 - 8e-10 38.7 14.5 1.6e-09 37.7 14.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFQ95037.1 - 3.4e-05 23.8 12.9 3.4e-05 23.8 12.9 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFQ95037.1 - 0.002 18.6 8.2 0.002 18.6 8.2 2.8 3 0 0 3 3 3 1 bZIP Maf transcription factor Sushi PF00084.20 KFQ95038.1 - 8.6e-59 196.0 57.5 2.6e-11 44.0 1.8 6.9 7 0 0 7 7 6 6 Sushi repeat (SCR repeat) Lectin_C PF00059.21 KFQ95038.1 - 6.3e-24 84.8 3.3 5.3e-23 81.8 3.3 2.6 1 0 0 1 1 1 1 Lectin C-type domain EGF PF00008.27 KFQ95038.1 - 4e-06 27.0 12.5 1.1e-05 25.6 8.9 4.1 2 0 0 2 2 2 1 EGF-like domain EGF_2 PF07974.13 KFQ95038.1 - 0.00016 22.0 8.6 0.00016 22.0 8.6 4.0 2 0 0 2 2 2 1 EGF-like domain EGF_3 PF12947.7 KFQ95038.1 - 0.01 16.0 2.2 0.01 16.0 2.2 5.5 7 0 0 7 7 7 0 EGF domain EGF_CA PF07645.15 KFQ95038.1 - 0.012 15.8 10.1 0.012 15.8 10.1 6.5 7 0 0 7 7 7 0 Calcium-binding EGF domain hEGF PF12661.7 KFQ95038.1 - 0.016 15.9 3.8 0.016 15.9 3.8 4.0 3 0 0 3 3 3 0 Human growth factor-like EGF GAD-like PF08887.11 KFQ95038.1 - 0.021 14.6 0.0 1.6 8.6 0.0 3.3 4 0 0 4 4 4 0 GAD-like domain HRM PF02793.22 KFQ95038.1 - 0.055 13.8 45.1 0.32 11.3 1.3 7.0 7 0 0 7 7 7 0 Hormone receptor domain Glug PF07581.12 KFQ95038.1 - 0.38 11.3 5.4 2.6e+02 2.4 0.0 5.1 5 0 0 5 5 5 0 The GLUG motif DUF5465 PF17553.2 KFQ95038.1 - 0.39 11.3 2.8 1.7e+02 3.2 0.0 4.6 4 0 0 4 4 3 0 Family of unknown function (DUF5465) NAD_binding_10 PF13460.6 KFQ95039.1 - 1.7e-05 24.8 0.0 2.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RGS PF00615.19 KFQ95040.1 - 1e-36 125.8 2.7 1.3e-36 125.4 2.7 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS-like PF09128.11 KFQ95040.1 - 0.012 15.4 0.1 0.016 14.9 0.1 1.1 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain DUF4929 PF16283.5 KFQ95040.1 - 0.022 13.8 0.1 0.028 13.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4929) Gag_p19 PF02228.16 KFQ95040.1 - 0.056 13.9 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Major core protein p19 RGS PF00615.19 KFQ95041.1 - 1.5e-36 125.2 1.5 2e-36 124.8 1.5 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain Sas6_CC PF18594.1 KFQ95041.1 - 0.06 13.1 0.2 0.14 12.0 0.2 1.6 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain RGS PF00615.19 KFQ95043.1 - 1.7e-40 138.0 7.4 1.9e-40 137.8 7.4 1.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain COMPASS-Shg1 PF05205.12 KFQ95043.1 - 0.016 15.9 0.3 0.022 15.4 0.3 1.2 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 RGS-like PF09128.11 KFQ95043.1 - 0.03 14.0 0.2 0.036 13.8 0.2 1.1 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Peptidase_C12 PF01088.21 KFQ95044.1 - 1e-60 205.1 0.0 1.9e-60 204.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KFQ95044.1 - 2e-20 72.4 4.8 4.1e-20 71.4 4.8 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases RcsD_ABL PF16359.5 KFQ95044.1 - 0.062 13.4 0.4 0.12 12.5 0.4 1.4 1 0 0 1 1 1 0 RcsD-ABL domain TROVE PF05731.11 KFQ95045.1 - 1.2e-52 179.5 0.5 5.7e-49 167.4 0.8 2.3 1 1 1 2 2 2 2 TROVE domain DUF2201 PF09967.9 KFQ95045.1 - 0.003 17.7 0.5 0.012 15.7 0.2 2.0 2 0 0 2 2 2 1 VWA-like domain (DUF2201) Glutaredoxin PF00462.24 KFQ95046.1 - 1.7e-19 69.8 0.1 2e-19 69.5 0.1 1.1 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 KFQ95046.1 - 3.1e-05 23.9 0.1 3.8e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.6 KFQ95046.1 - 0.0041 17.6 0.0 0.0049 17.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 KFQ95046.1 - 0.0052 17.2 0.0 0.007 16.8 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 KFQ95046.1 - 0.024 14.4 0.7 1 9.1 0.0 2.0 1 1 0 2 2 2 0 DSBA-like thioredoxin domain FACT-Spt16_Nlob PF14826.6 KFQ95046.1 - 0.05 13.4 0.0 0.058 13.2 0.0 1.1 1 0 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain zf-C2H2_10 PF16588.5 KFQ95046.1 - 0.056 13.2 1.2 0.092 12.5 1.2 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger Thioredoxin PF00085.20 KFQ95046.1 - 0.056 13.4 0.0 0.057 13.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DUF2117 PF09890.9 KFQ95046.1 - 0.073 12.5 0.0 0.081 12.4 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2117) Thioredoxin_7 PF13899.6 KFQ95046.1 - 0.12 12.6 0.2 0.28 11.4 0.2 1.7 1 1 0 1 1 1 0 Thioredoxin-like THF_DHG_CYH PF00763.23 KFQ95046.1 - 0.13 12.5 0.0 0.17 12.2 0.0 1.1 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain CDC73_N PF16050.5 KFQ95047.1 - 5.4e-107 357.5 4.6 7.5e-107 357.0 4.6 1.2 1 0 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal CDC73_C PF05179.14 KFQ95047.1 - 1.7e-50 170.7 0.0 3.4e-50 169.8 0.0 1.5 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal Galactosyl_T PF01762.21 KFQ95048.1 - 9.7e-66 221.3 0.0 1.4e-65 220.8 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase zf-RVT PF13966.6 KFQ95050.1 - 0.0025 18.5 0.4 0.0054 17.4 0.4 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase L_protein_N PF15518.6 KFQ95050.1 - 0.0068 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 L protein N-terminus FolB PF02152.18 KFQ95050.1 - 0.013 16.0 0.6 0.025 15.1 0.2 1.6 2 0 0 2 2 2 0 Dihydroneopterin aldolase AHJR-like PF18743.1 KFQ95050.1 - 0.017 14.7 0.2 0.026 14.1 0.2 1.3 1 0 0 1 1 1 0 REase_AHJR-like BK_channel_a PF03493.18 KFQ95051.1 - 4.1e-32 110.3 1.6 8.7e-32 109.2 0.2 2.4 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 KFQ95051.1 - 1.5e-12 47.3 4.2 7.8e-12 45.0 4.1 2.2 2 0 0 2 2 2 1 Ion channel Castor_Poll_mid PF06241.12 KFQ95051.1 - 0.05 13.6 0.0 3.1 7.8 0.0 2.8 2 0 0 2 2 2 0 Castor and Pollux, part of voltage-gated ion channel Sushi PF00084.20 KFQ95052.1 - 5.9e-157 510.3 144.1 3.1e-13 50.1 1.9 20.1 19 1 1 20 20 20 19 Sushi repeat (SCR repeat) DciA PF05258.12 KFQ95052.1 - 0.18 12.2 0.0 0.43 11.0 0.0 1.5 1 0 0 1 1 1 0 Dna[CI] antecedent, DciA IRF-3 PF10401.9 KFQ95053.1 - 9.5e-18 64.6 0.0 1.2e-17 64.3 0.0 1.1 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IFRD PF05004.13 KFQ95054.1 - 0.0054 15.9 0.0 0.1 11.7 0.0 2.2 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) Xpo1 PF08389.12 KFQ95054.1 - 0.06 13.4 0.9 14 5.8 0.0 3.3 2 1 1 3 3 3 0 Exportin 1-like protein Xpo1 PF08389.12 KFQ95055.1 - 7.1e-25 87.8 0.5 1.1e-24 87.2 0.5 1.3 1 0 0 1 1 1 1 Exportin 1-like protein Tetraspanin PF00335.20 KFQ95056.1 - 2.2e-36 125.7 0.0 2.8e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Tetraspanin family UL42 PF17638.2 KFQ95056.1 - 0.00061 19.8 0.0 0.00095 19.1 0.0 1.3 1 0 0 1 1 1 1 HCMV UL42 AdoHcyase PF05221.17 KFQ95057.1 - 2.6e-34 118.7 0.1 5.5e-34 117.7 0.1 1.5 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase Nrf1_DNA-bind PF10491.9 KFQ95059.1 - 1.4e-116 387.6 0.1 2.1e-116 387.0 0.1 1.3 1 0 0 1 1 1 1 NLS-binding and DNA-binding and dimerisation domains of Nrf1 Nrf1_activ_bdg PF10492.9 KFQ95059.1 - 0.00088 19.9 6.7 0.00088 19.9 6.7 5.7 3 2 1 4 4 4 1 Nrf1 activator activation site binding domain DUF5008 PF16400.5 KFQ95059.1 - 0.054 13.6 0.0 0.21 11.7 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5008) DUF3459 PF11941.8 KFQ95059.1 - 0.094 13.1 0.6 0.37 11.2 0.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Peptidase_M23 PF01551.22 KFQ95059.1 - 0.45 10.8 3.4 0.87 9.8 1.0 2.4 1 1 1 2 2 2 0 Peptidase family M23 UQ_con PF00179.26 KFQ95061.1 - 1.5e-37 128.3 0.0 1.9e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Uteroglobin PF01099.17 KFQ95061.1 - 0.14 12.5 1.2 0.27 11.6 0.9 1.6 1 1 0 2 2 2 0 Uteroglobin family zf-C3HC PF07967.13 KFQ95062.1 - 7.5e-35 119.9 1.4 7.5e-35 119.9 1.4 3.3 3 1 0 3 3 3 1 C3HC zinc finger-like Rsm1 PF08600.10 KFQ95062.1 - 7.8e-15 54.8 10.1 6.8e-10 39.0 0.3 3.4 3 0 0 3 3 3 2 Rsm1-like Yippee-Mis18 PF03226.14 KFQ95062.1 - 4.6 7.5 8.1 23 5.3 2.9 2.5 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Kelch_1 PF01344.25 KFQ95063.1 - 1.5e-41 139.7 9.7 7.6e-10 38.2 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KFQ95063.1 - 1.2e-39 133.3 4.9 4.5e-07 29.9 0.0 6.1 5 1 1 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KFQ95063.1 - 3.2e-36 123.1 11.8 1.9e-10 40.6 0.0 5.8 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KFQ95063.1 - 1.9e-32 110.9 12.9 2.1e-07 31.1 0.0 7.0 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KFQ95063.1 - 2.4e-32 110.4 7.4 1.5e-05 24.9 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 KFQ95063.1 - 3.6e-27 93.3 12.3 7.5e-06 25.7 0.1 6.8 5 2 1 6 6 6 6 Kelch motif CytochromB561_N PF09786.9 KFQ95064.1 - 4.8e-152 507.9 6.3 5.8e-152 507.6 6.3 1.0 1 0 0 1 1 1 1 Cytochrome B561, N terminal NPCC PF08058.11 KFQ95064.1 - 0.0096 16.0 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore complex component Peptidase_M14 PF00246.24 KFQ95065.1 - 3.1e-92 309.5 0.1 3.9e-92 309.1 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KFQ95065.1 - 9.1e-22 77.2 0.1 3.4e-21 75.4 0.0 2.0 2 0 0 2 2 2 1 Carboxypeptidase activation peptide P_C PF06640.11 KFQ95065.1 - 0.041 14.0 0.1 0.069 13.3 0.1 1.2 1 0 0 1 1 1 0 P protein C-terminus Peptidase_M14 PF00246.24 KFQ95066.1 - 8.1e-92 308.1 0.0 9.5e-92 307.9 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KFQ95066.1 - 5.9e-15 55.4 0.0 1.3e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Rhodanese PF00581.20 KFQ95067.1 - 1.1e-11 45.2 0.0 2.3e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Abhydrolase_1 PF00561.20 KFQ95068.1 - 4.7e-07 29.7 0.1 1.6e-06 28.0 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFQ95068.1 - 5.7e-07 30.4 0.1 6.8e-07 30.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFQ95068.1 - 2.4e-05 23.7 0.0 0.0001 21.6 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 KFQ95068.1 - 0.0065 15.5 0.0 0.0087 15.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) HTH_34 PF13601.6 KFQ95068.1 - 0.17 12.1 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain Adaptin_N PF01602.20 KFQ95069.1 - 3.3e-137 458.2 9.3 4e-137 457.9 9.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KFQ95069.1 - 3.5e-63 212.3 0.1 7.9e-63 211.1 0.1 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KFQ95069.1 - 3.3e-40 136.8 0.0 8.7e-40 135.4 0.0 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KFQ95069.1 - 9.2e-17 61.2 0.2 8.5e-09 35.7 0.0 5.1 3 2 4 7 7 7 3 HEAT repeats Cnd1 PF12717.7 KFQ95069.1 - 1.2e-10 41.7 14.6 0.0021 18.2 0.5 4.9 3 1 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KFQ95069.1 - 2.2e-08 34.4 3.8 0.00045 20.7 0.3 4.7 5 0 0 5 5 5 2 HEAT-like repeat HEAT PF02985.22 KFQ95069.1 - 7.6e-06 25.8 7.2 0.5 10.8 0.1 6.2 6 0 0 6 6 6 2 HEAT repeat MOR2-PAG1_C PF14225.6 KFQ95069.1 - 0.013 15.4 0.1 0.043 13.7 0.1 1.9 1 0 0 1 1 1 0 Cell morphogenesis C-terminal HEAT_PBS PF03130.16 KFQ95069.1 - 0.055 14.2 1.7 3 8.8 0.1 4.1 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat UNC45-central PF11701.8 KFQ95069.1 - 0.072 13.0 3.5 0.31 11.0 0.3 3.3 3 1 1 4 4 4 0 Myosin-binding striated muscle assembly central Cnd3 PF12719.7 KFQ95069.1 - 0.077 12.2 3.9 2.2 7.4 0.0 3.2 2 1 1 3 3 3 0 Nuclear condensing complex subunits, C-term domain UvrD_C PF13361.6 KFQ95070.1 - 3.1e-13 49.8 0.9 1.1e-12 48.0 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KFQ95070.1 - 5.5e-13 49.5 0.0 1.3e-12 48.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KFQ95070.1 - 2.6e-12 46.9 4.8 2e-08 34.1 0.4 2.9 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain F-box-like PF12937.7 KFQ95070.1 - 3e-11 43.0 0.9 3e-10 39.8 1.2 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFQ95070.1 - 6.3e-10 38.7 2.7 8.7e-10 38.2 0.8 2.3 2 0 0 2 2 2 1 F-box domain UvrD_C_2 PF13538.6 KFQ95070.1 - 7e-10 38.6 0.2 2.3e-08 33.7 0.2 2.7 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KFQ95070.1 - 2.4e-07 30.8 0.0 0.042 13.6 0.0 3.9 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KFQ95070.1 - 2.6e-07 30.6 0.0 0.011 15.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 KFQ95070.1 - 2.2e-06 27.5 0.1 0.00024 20.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 KFQ95070.1 - 1.8e-05 24.3 0.1 0.21 11.0 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.6 KFQ95070.1 - 0.0019 18.1 0.5 1.2 8.8 0.2 2.5 2 0 0 2 2 2 2 AAA domain F-box_4 PF15966.5 KFQ95070.1 - 0.02 14.8 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 F-box AAA_22 PF13401.6 KFQ95070.1 - 0.037 14.3 0.0 0.48 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 KFQ95070.1 - 0.62 10.0 4.2 2.1 8.3 4.2 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Ank_4 PF13637.6 KFQ95071.1 - 1.5e-62 207.2 19.6 5.2e-12 46.0 0.0 6.5 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFQ95071.1 - 1.9e-52 175.8 6.0 1.4e-12 48.0 0.0 5.1 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFQ95071.1 - 8.2e-46 148.7 7.5 1.3e-05 25.2 0.0 9.4 9 0 0 9 9 9 8 Ankyrin repeat Ank PF00023.30 KFQ95071.1 - 3e-44 147.6 9.7 1.3e-06 28.5 0.0 9.2 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 KFQ95071.1 - 1e-38 130.9 10.4 2.9e-08 33.8 0.0 7.6 1 1 6 8 8 8 8 Ankyrin repeats (many copies) DUF249 PF03158.13 KFQ95071.1 - 0.015 15.0 0.0 3.4 7.3 0.0 2.9 3 1 0 3 3 3 0 Multigene family 530 protein GDI PF00996.18 KFQ95072.1 - 4.8e-227 753.6 0.1 5.6e-227 753.4 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor SH3_14 PF18343.1 KFQ95072.1 - 0.033 14.3 2.6 3.4 7.8 0.3 3.2 2 1 0 3 3 3 0 Dda helicase SH3 domain Myc_N PF01056.18 KFQ95072.1 - 0.036 14.0 0.0 0.098 12.5 0.0 1.6 2 0 0 2 2 2 0 Myc amino-terminal region Amino_oxidase PF01593.24 KFQ95072.1 - 0.057 12.7 0.0 0.076 12.3 0.0 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase DUF3715 PF12509.8 KFQ95073.1 - 4.6e-05 23.5 0.1 9.7e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3715) Ank_2 PF12796.7 KFQ95075.1 - 1.3e-52 176.3 16.4 1.2e-15 57.8 2.9 3.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ95075.1 - 8.4e-40 134.6 9.1 2.1e-10 40.9 0.0 4.7 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KFQ95075.1 - 9e-37 123.9 12.1 9.3e-07 29.0 0.1 7.0 7 1 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 KFQ95075.1 - 4.1e-27 91.2 4.9 0.00014 22.0 0.0 6.8 6 1 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 KFQ95075.1 - 5.9e-25 87.0 4.6 3e-06 27.4 0.1 5.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFQ95075.1 - 7e-10 39.1 0.9 1.2e-09 38.3 0.9 1.4 1 0 0 1 1 1 1 SOCS box EF-hand_1 PF00036.32 KFQ95076.1 - 2.5e-40 133.0 6.4 4.8e-10 38.3 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFQ95076.1 - 4.1e-35 120.1 1.3 8.8e-19 67.7 0.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFQ95076.1 - 3.7e-32 110.0 8.9 5.4e-14 51.8 0.4 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KFQ95076.1 - 1.3e-30 102.6 2.7 1.9e-09 36.7 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFQ95076.1 - 4.5e-23 79.7 2.8 1.2e-06 27.7 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KFQ95076.1 - 5.3e-15 55.5 0.1 5.8e-08 32.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KFQ95076.1 - 6.8e-08 32.4 0.2 0.00098 19.0 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFQ95076.1 - 7.8e-07 29.4 0.2 0.0014 19.0 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 KFQ95076.1 - 1.4e-05 25.9 0.0 0.00047 21.0 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.10 KFQ95076.1 - 1.8e-05 24.8 0.5 4.9e-05 23.3 0.1 2.0 2 2 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.13 KFQ95076.1 - 0.0001 22.2 0.0 0.27 11.3 0.0 3.2 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) Caleosin PF05042.13 KFQ95076.1 - 0.00084 19.3 0.2 0.35 10.8 0.0 3.0 1 1 1 3 3 3 1 Caleosin related protein DUF3349 PF11829.8 KFQ95076.1 - 0.00086 20.0 0.1 4.7 8.1 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Dockerin_1 PF00404.18 KFQ95076.1 - 0.0013 18.8 1.5 0.051 13.8 0.2 2.9 1 1 3 4 4 4 1 Dockerin type I domain RNA_pol_Rpb4 PF03874.16 KFQ95076.1 - 0.0015 18.8 0.4 0.8 10.0 0.2 2.6 2 1 0 2 2 2 1 RNA polymerase Rpb4 TerB PF05099.13 KFQ95076.1 - 0.0065 16.4 0.4 3.3 7.7 0.1 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF4497 PF14924.6 KFQ95076.1 - 0.007 16.8 0.0 1.5 9.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4497) DUF5580 PF17743.1 KFQ95076.1 - 0.019 13.5 0.0 0.02 13.4 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 KFQ95076.1 - 0.026 14.4 0.2 0.38 10.6 0.1 2.1 1 1 0 2 2 2 0 SurA N-terminal domain Fe_hyd_lg_C PF02906.14 KFQ95076.1 - 0.045 13.4 0.1 0.12 12.1 0.1 1.7 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain MotA_activ PF09114.10 KFQ95076.1 - 0.11 12.6 0.0 0.83 9.8 0.0 2.0 2 0 0 2 2 2 0 Transcription factor MotA, activation domain RhoGEF PF00621.20 KFQ95077.1 - 4.8e-37 127.9 0.0 8.5e-37 127.2 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 KFQ95077.1 - 1.5e-08 34.6 0.1 1.5e-07 31.3 0.1 2.6 2 1 0 2 2 2 1 Pleckstrin homology domain PH_5 PF15405.6 KFQ95077.1 - 4.7e-08 33.2 0.3 2.9e-07 30.7 0.3 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFQ95077.1 - 2.6e-07 31.1 0.0 4.9e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 KFQ95077.1 - 0.0062 16.5 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 PH domain Tubulin PF00091.25 KFQ95078.1 - 3e-68 229.9 0.0 4e-68 229.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFQ95078.1 - 4.8e-51 172.2 0.0 7.7e-51 171.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFQ95078.1 - 0.0046 16.7 0.0 0.0088 15.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain hNIFK_binding PF12196.8 KFQ95079.1 - 0.09 12.3 0.4 0.15 11.6 0.4 1.4 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK Tubulin_C PF03953.17 KFQ95080.1 - 3.6e-51 172.6 0.0 7.1e-51 171.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 KFQ95080.1 - 1.9e-47 162.1 0.0 4.6e-47 160.8 0.0 1.6 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain CRF PF00473.17 KFQ95082.1 - 4.3e-14 52.3 1.3 9.1e-14 51.2 1.3 1.6 1 0 0 1 1 1 1 Corticotropin-releasing factor family Phage_clamp_A PF16790.5 KFQ95082.1 - 0.032 14.7 0.1 0.045 14.2 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage clamp loader A subunit UAA PF08449.11 KFQ95083.1 - 9.8e-107 356.6 19.5 1.1e-106 356.5 19.5 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 KFQ95083.1 - 9.3e-06 25.2 15.6 1.7e-05 24.3 4.1 2.0 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 KFQ95083.1 - 0.05 13.8 30.2 0.091 12.9 14.8 3.0 2 1 0 2 2 2 0 EamA-like transporter family Guanylate_kin PF00625.21 KFQ95084.1 - 1.2e-25 90.3 0.0 3.6e-25 88.7 0.0 1.9 2 0 0 2 2 2 1 Guanylate kinase LRR_4 PF12799.7 KFQ95084.1 - 3.7e-22 78.0 37.5 4.8e-07 30.0 2.0 6.1 5 1 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFQ95084.1 - 1.9e-19 69.8 9.6 2.5e-16 59.7 4.1 2.9 2 1 1 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 KFQ95084.1 - 2.7e-15 55.9 39.1 2.6e-05 23.9 7.9 5.8 3 1 4 7 7 7 6 Leucine rich repeat LRR_6 PF13516.6 KFQ95084.1 - 2e-07 30.5 31.9 0.037 14.1 0.5 8.2 8 1 1 9 9 9 5 Leucine Rich repeat LRR_1 PF00560.33 KFQ95084.1 - 4.8 8.1 26.7 24 6.0 0.4 8.1 7 3 0 7 7 7 0 Leucine Rich Repeat Sec8_exocyst PF04048.14 KFQ95086.1 - 4.1e-19 68.9 4.0 5.5e-19 68.5 1.5 2.1 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Zw10 PF06248.13 KFQ95086.1 - 6.7e-06 24.9 7.3 6.7e-06 24.9 7.3 2.0 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 Vps54_N PF10475.9 KFQ95086.1 - 0.00046 19.6 6.2 0.00046 19.6 6.2 2.0 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COG5 PF10392.9 KFQ95086.1 - 0.0012 19.0 2.1 0.0012 19.0 2.1 3.2 2 1 1 3 3 3 1 Golgi transport complex subunit 5 Dor1 PF04124.12 KFQ95086.1 - 0.022 13.5 11.9 0.014 14.1 6.6 2.0 2 0 0 2 2 2 0 Dor1-like family PEP-utilisers_N PF05524.13 KFQ95086.1 - 0.037 14.2 0.3 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal AAA_14 PF13173.6 KFQ95086.1 - 0.074 13.1 0.7 0.84 9.7 0.2 2.6 1 1 1 2 2 2 0 AAA domain T3SS_needle_E PF08988.10 KFQ95086.1 - 0.1 12.7 1.9 2.6 8.3 0.2 3.1 2 1 1 3 3 3 0 Type III secretion system, cytoplasmic E component of needle Ead_Ea22 PF13935.6 KFQ95086.1 - 0.17 12.5 3.5 0.43 11.2 0.8 2.6 2 1 1 3 3 3 0 Ead/Ea22-like protein Vps51 PF08700.11 KFQ95086.1 - 0.48 10.5 7.5 1.8 8.7 1.3 2.9 3 0 0 3 3 3 0 Vps51/Vps67 ResIII PF04851.15 KFQ95086.1 - 0.79 9.7 4.2 0.36 10.8 0.9 2.1 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DASH_Duo1 PF08651.10 KFQ95086.1 - 0.9 9.4 6.7 2.5 8.0 0.5 2.9 3 0 0 3 3 3 0 DASH complex subunit Duo1 YojJ PF10372.9 KFQ95086.1 - 1.1 9.4 4.7 1.5 8.9 0.1 3.0 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus Cauli_AT PF03233.13 KFQ95086.1 - 1.4 8.8 8.3 0.35 10.8 0.7 2.7 3 0 0 3 3 3 0 Aphid transmission protein Prominin PF05478.11 KFQ95086.1 - 4.7 5.0 12.3 2.6 5.9 5.6 2.1 1 1 1 2 2 2 0 Prominin 5_3_exonuc PF01367.20 KFQ95086.1 - 5.4 7.7 6.2 27 5.5 0.0 3.4 3 1 1 4 4 4 0 5'-3' exonuclease, C-terminal SAM fold Exonuc_VII_L PF02601.15 KFQ95086.1 - 7.5 6.0 9.8 73 2.8 9.8 2.1 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF737 PF05300.11 KFQ95088.1 - 2e-48 165.4 34.8 6.1e-37 127.9 28.7 2.4 2 1 1 3 3 3 2 Protein of unknown function (DUF737) CHCH PF06747.13 KFQ95088.1 - 0.0044 17.1 2.2 0.0085 16.2 2.2 1.4 1 0 0 1 1 1 1 CHCH domain PIN_9 PF18477.1 KFQ95088.1 - 0.15 12.4 1.9 9.1 6.6 1.3 2.4 2 0 0 2 2 2 0 PIN like domain Exonuc_VII_L PF02601.15 KFQ95088.1 - 2.1 7.8 13.2 2.8 7.4 13.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit MAP7 PF05672.11 KFQ95088.1 - 2.4 7.8 33.2 3.6 7.2 33.2 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Jnk-SapK_ap_N PF09744.9 KFQ95088.1 - 3.1 8.0 23.3 7.6 6.7 23.4 1.9 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF2570 PF10828.8 KFQ95088.1 - 3.6 7.4 10.8 0.25 11.2 3.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) Sema PF01403.19 KFQ95089.1 - 1.1e-61 209.0 0.0 1.3e-61 208.7 0.0 1.1 1 0 0 1 1 1 1 Sema domain Plexin_cytopl PF08337.12 KFQ95090.1 - 1.6e-262 872.1 2.7 2e-262 871.8 2.7 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.24 KFQ95090.1 - 7.5e-44 147.7 6.0 1.4e-13 50.7 0.1 6.1 6 0 0 6 6 6 4 IPT/TIG domain TIG_2 PF18020.1 KFQ95090.1 - 3.3e-35 120.6 0.3 5.3e-34 116.7 0.1 2.9 2 0 0 2 2 2 1 TIG domain found in plexin PSI PF01437.25 KFQ95090.1 - 5.7e-23 81.2 56.8 1.9e-10 41.1 15.1 3.6 3 0 0 3 3 3 3 Plexin repeat TIG_plexin PF17960.1 KFQ95090.1 - 1e-20 73.5 14.6 1.3e-20 73.2 0.1 5.2 7 0 0 7 7 7 2 TIG domain PSI_integrin PF17205.3 KFQ95090.1 - 0.0007 19.3 49.6 0.0012 18.5 13.7 3.6 3 0 0 3 3 3 3 Integrin plexin domain RasGAP PF00616.19 KFQ95090.1 - 0.0022 17.7 1.0 0.46 10.2 0.9 2.7 2 1 0 2 2 2 2 GTPase-activator protein for Ras-like GTPase CD34_antigen PF06365.12 KFQ95092.1 - 9.7e-62 208.3 1.2 1.6e-61 207.6 1.2 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family Muskelin_N PF06588.11 KFQ95093.1 - 6e-89 297.2 0.3 9.4e-89 296.6 0.3 1.3 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_3 PF13415.6 KFQ95093.1 - 2.6e-21 75.4 4.8 2.7e-10 40.3 0.0 5.1 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KFQ95093.1 - 6.1e-18 64.1 18.5 1.4e-06 27.7 0.3 6.1 6 1 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 KFQ95093.1 - 4.2e-16 58.6 5.4 0.0053 17.0 0.1 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 KFQ95093.1 - 3.3e-15 55.8 9.3 5.8e-05 23.0 0.1 6.1 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KFQ95093.1 - 1.1e-14 54.0 11.8 0.00032 20.6 0.2 6.6 6 1 0 6 6 6 4 Kelch motif F5_F8_type_C PF00754.25 KFQ95093.1 - 2.4e-07 30.9 0.0 5.2e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain Kelch_2 PF07646.15 KFQ95093.1 - 1.4e-05 24.9 12.3 0.1 12.6 0.1 6.1 6 1 1 7 7 7 2 Kelch motif Sad1_UNC PF07738.13 KFQ95093.1 - 0.029 14.4 0.0 0.075 13.1 0.0 1.6 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Endonuclease_NS PF01223.23 KFQ95095.1 - 1.6e-31 109.9 2.1 2.7e-31 109.1 2.1 1.4 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 KFQ95095.1 - 0.015 15.4 1.4 0.031 14.4 1.4 1.6 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease Sushi PF00084.20 KFQ95096.1 - 8e-08 32.8 0.5 9.7e-08 32.5 0.5 1.1 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) G-patch PF01585.23 KFQ95098.1 - 3.4e-13 49.3 1.5 7.6e-13 48.1 1.5 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KFQ95098.1 - 5.3e-05 23.0 0.1 0.0001 22.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nucleo_P87 PF07267.11 KFQ95098.1 - 2.7 6.7 5.4 3.6 6.3 5.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.14 KFQ95098.1 - 6.2 5.0 6.1 9.2 4.4 6.1 1.2 1 0 0 1 1 1 0 CDC45-like protein 6PF2K PF01591.18 KFQ95099.1 - 1.4e-103 345.0 0.4 2.4e-103 344.2 0.4 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KFQ95099.1 - 5.7e-43 146.9 0.0 7.9e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KFQ95099.1 - 6.7e-07 29.6 0.0 1.7e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KFQ95099.1 - 0.0021 17.6 0.0 0.0035 16.8 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 KFQ95099.1 - 0.02 14.2 0.0 0.096 12.0 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin His_Phos_2 PF00328.22 KFQ95099.1 - 0.055 12.8 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) AAA_17 PF13207.6 KFQ95099.1 - 0.17 12.3 0.0 0.4 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 KFQ95100.1 - 3.3e-42 144.7 0.0 6e-42 143.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain C1_1 PF00130.22 KFQ95100.1 - 1.3e-32 111.4 22.5 3.1e-17 62.2 6.7 2.9 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_Tyr PF07714.17 KFQ95100.1 - 4.1e-27 95.1 0.4 1.3e-26 93.5 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase C1_2 PF03107.16 KFQ95100.1 - 5.9e-05 23.3 16.6 0.0092 16.3 5.7 2.9 2 0 0 2 2 2 2 C1 domain zf-RING_9 PF13901.6 KFQ95100.1 - 0.00012 22.1 15.8 0.0012 18.9 5.4 2.5 2 0 0 2 2 2 2 Putative zinc-RING and/or ribbon Zf_RING PF16744.5 KFQ95100.1 - 0.0043 17.1 2.7 0.0043 17.1 2.7 2.5 2 0 0 2 2 2 1 KIAA1045 RING finger PHD PF00628.29 KFQ95100.1 - 0.0046 16.8 21.1 0.052 13.5 6.6 2.9 2 0 0 2 2 2 2 PHD-finger Haspin_kinase PF12330.8 KFQ95100.1 - 0.012 14.6 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KFQ95100.1 - 0.022 14.1 0.2 0.68 9.2 0.0 2.2 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 KFQ95100.1 - 0.033 14.1 0.0 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-RING-like PF08746.11 KFQ95100.1 - 0.052 13.9 24.0 0.11 12.9 8.3 3.0 2 0 0 2 2 2 0 RING-like domain DZR PF12773.7 KFQ95100.1 - 0.17 11.9 19.5 0.029 14.4 2.8 3.0 3 0 0 3 3 2 0 Double zinc ribbon DUF2318 PF10080.9 KFQ95100.1 - 0.53 10.4 11.3 0.25 11.5 1.5 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) zf-ACC PF17848.1 KFQ95100.1 - 2.7 8.1 8.8 41 4.4 1.8 3.7 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain PHD_2 PF13831.6 KFQ95100.1 - 9.7 5.8 16.3 0.99 9.0 1.9 3.0 3 0 0 3 3 3 0 PHD-finger MBT PF02820.18 KFQ95101.1 - 4.1e-92 302.6 5.7 1.2e-23 83.2 0.1 4.7 5 0 0 5 5 5 4 mbt repeat SLED PF12140.8 KFQ95101.1 - 8.3e-39 132.6 0.1 1.6e-38 131.7 0.1 1.5 1 0 0 1 1 1 1 SLED domain SAM_1 PF00536.30 KFQ95101.1 - 2.5e-08 34.2 0.0 5.2e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFQ95101.1 - 2.4e-05 24.2 0.0 8.3e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.17 KFQ95101.1 - 0.00014 21.9 0.0 0.00033 20.7 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 KFQ95101.1 - 0.012 15.9 2.1 0.012 15.8 0.1 2.1 2 0 0 2 2 2 0 Ste50p, sterile alpha motif STIMATE PF12400.8 KFQ95102.1 - 3.7e-33 114.7 10.9 5.2e-33 114.2 10.9 1.2 1 0 0 1 1 1 1 STIMATE family Vpu PF00558.19 KFQ95102.1 - 0.074 12.8 2.4 0.19 11.5 0.0 2.4 2 0 0 2 2 2 0 Vpu protein ITI_HC_C PF06668.12 KFQ95103.1 - 5.5e-72 241.4 0.3 1.1e-71 240.4 0.3 1.6 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus VIT PF08487.10 KFQ95103.1 - 3.2e-29 101.4 1.0 6.8e-29 100.3 1.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 KFQ95103.1 - 6.3e-21 75.4 0.2 1.3e-20 74.4 0.2 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFQ95103.1 - 4.8e-18 65.6 0.0 7.9e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFQ95103.1 - 2.5e-12 47.4 0.1 8.6e-12 45.7 0.1 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KFQ95103.1 - 0.00021 20.8 0.0 0.0004 19.9 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Kin17_mid PF10357.9 KFQ95104.1 - 1.4e-50 170.4 3.2 1.4e-50 170.4 3.2 1.9 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 KFQ95104.1 - 7.7e-23 80.4 6.2 4.1e-22 78.1 6.7 1.9 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain KOW PF00467.29 KFQ95104.1 - 0.00062 19.6 3.6 0.0012 18.8 0.0 3.0 2 1 1 3 3 3 1 KOW motif SecM PF06558.12 KFQ95104.1 - 0.0032 17.6 0.0 0.0062 16.6 0.0 1.5 1 0 0 1 1 1 1 Secretion monitor precursor protein (SecM) Caskin-tail PF16632.5 KFQ95104.1 - 0.052 14.0 0.4 0.23 11.9 0.4 2.1 1 0 0 1 1 1 0 C-terminal region of Caskin zf-met PF12874.7 KFQ95104.1 - 0.056 13.9 9.0 0.13 12.7 9.0 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFQ95104.1 - 0.36 11.2 8.5 0.78 10.1 8.5 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFQ95104.1 - 4.2 7.8 9.9 0.14 12.5 2.6 2.3 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) ATP-synt PF00231.19 KFQ95105.1 - 3.9e-81 272.8 3.7 4.4e-81 272.7 3.7 1.0 1 0 0 1 1 1 1 ATP synthase Bromo_TP PF07524.13 KFQ95106.1 - 3.2e-16 59.1 0.0 4.8e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated PHD PF00628.29 KFQ95106.1 - 9.3e-11 41.5 7.1 2.6e-10 40.0 7.1 1.8 1 0 0 1 1 1 1 PHD-finger RNA_pol_Rpc4 PF05132.14 KFQ95106.1 - 0.0037 17.7 13.8 0.0037 17.7 13.8 5.9 5 1 1 6 6 6 1 RNA polymerase III RPC4 PHD_2 PF13831.6 KFQ95106.1 - 0.0057 16.2 1.8 0.0057 16.2 1.8 2.1 2 0 0 2 2 2 1 PHD-finger MACPF PF01823.19 KFQ95107.1 - 1e-23 84.5 0.0 1.6e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 MAC/Perforin domain DTC PF18102.1 KFQ95108.1 - 3.5e-58 195.5 0.0 6.1e-58 194.7 0.0 1.4 1 0 0 1 1 1 1 Deltex C-terminal domain zf-RING_UBOX PF13445.6 KFQ95108.1 - 2.3e-08 33.9 1.1 6.1e-08 32.6 1.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFQ95108.1 - 8.4e-08 32.0 1.4 1.8e-07 30.9 1.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ95108.1 - 9.1e-08 32.3 1.6 3.4e-07 30.5 1.6 2.0 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFQ95108.1 - 2.8e-06 27.5 0.9 2.8e-06 27.5 0.9 1.8 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFQ95108.1 - 2.8e-05 24.0 1.5 6.3e-05 22.9 1.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFQ95108.1 - 2.8e-05 23.9 2.7 0.015 15.1 0.8 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFQ95108.1 - 0.00016 21.3 4.3 0.011 15.4 0.7 2.6 2 0 0 2 2 2 2 RING-like zinc finger zf-ANAPC11 PF12861.7 KFQ95108.1 - 0.0002 21.4 1.6 0.00041 20.3 1.4 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KFQ95108.1 - 0.0034 17.5 3.0 0.013 15.7 0.9 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KFQ95108.1 - 0.015 14.9 0.3 0.015 14.9 0.3 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-UDP PF14569.6 KFQ95108.1 - 0.016 15.3 1.4 0.018 15.1 0.1 1.7 2 0 0 2 2 1 0 Zinc-binding RING-finger Trm112p PF03966.16 KFQ95108.1 - 0.057 14.0 0.1 0.11 13.0 0.1 1.5 1 0 0 1 1 1 0 Trm112p-like protein FANCL_C PF11793.8 KFQ95108.1 - 0.065 13.4 1.4 0.22 11.8 1.4 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 KFQ95108.1 - 0.083 12.8 0.8 0.083 12.8 0.8 2.0 2 0 0 2 2 2 0 PHD-finger Prok-RING_4 PF14447.6 KFQ95108.1 - 0.083 12.8 2.6 0.35 10.8 2.6 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KFQ95108.1 - 0.094 12.5 1.4 0.16 11.8 0.2 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KFQ95108.1 - 0.33 10.8 3.4 3.6 7.5 0.4 2.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) ADK_lid PF05191.14 KFQ95108.1 - 0.81 9.7 3.9 3.6 7.7 0.1 3.1 3 0 0 3 3 3 0 Adenylate kinase, active site lid CNTF PF01110.17 KFQ95109.1 - 7e-78 260.5 0.3 7.7e-78 260.3 0.3 1.0 1 0 0 1 1 1 1 Ciliary neurotrophic factor zf-C2H2 PF00096.26 KFQ95110.1 - 4.7e-16 58.3 33.2 0.00056 20.2 0.8 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ95110.1 - 8.4e-12 45.0 24.3 0.00039 20.7 0.3 4.6 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ95110.1 - 3.1e-09 36.9 33.0 0.039 14.8 0.7 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFQ95110.1 - 0.0042 17.0 18.1 0.06 13.4 0.3 4.5 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFQ95110.1 - 0.013 15.7 5.4 0.013 15.7 5.4 2.8 1 1 2 3 3 3 0 C2H2-type zinc ribbon zinc_ribbon_15 PF17032.5 KFQ95110.1 - 0.024 15.4 11.0 0.085 13.6 1.4 2.7 1 1 1 2 2 2 0 zinc-ribbon family CpXC PF14353.6 KFQ95110.1 - 0.027 14.5 9.5 6.9 6.7 1.4 4.5 2 2 1 3 3 3 0 CpXC protein zf-C2HC_2 PF13913.6 KFQ95110.1 - 0.032 14.1 14.7 0.82 9.6 0.3 4.6 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 KFQ95110.1 - 0.076 13.1 14.3 0.16 12.1 0.1 3.5 3 1 0 3 3 3 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 KFQ95110.1 - 0.083 13.2 0.5 0.083 13.2 0.5 2.9 3 0 0 3 3 2 0 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFQ95110.1 - 0.17 12.2 2.6 8.5 6.7 0.7 2.6 2 0 0 2 2 2 0 BolA-like protein Prok-RING_1 PF14446.6 KFQ95110.1 - 0.36 10.8 5.5 0.46 10.5 0.1 3.1 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-Di19 PF05605.12 KFQ95110.1 - 0.73 10.2 23.1 0.2 11.9 4.9 3.8 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding FOXP-CC PF16159.5 KFQ95110.1 - 1 10.0 8.0 2.6 8.7 0.7 3.4 2 1 1 3 3 3 0 FOXP coiled-coil domain zf_C2H2_ZHX PF18387.1 KFQ95110.1 - 4.6 7.0 9.8 1.9 8.2 0.2 3.2 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain LIM PF00412.22 KFQ95111.1 - 4.7e-55 183.7 34.4 1.8e-15 56.9 4.2 5.0 5 0 0 5 5 5 5 LIM domain zf_C2H2_13 PF18508.1 KFQ95111.1 - 1.5 8.5 8.0 4.2 7.1 0.4 3.8 3 0 0 3 3 3 0 Zinc finger domain WRC PF08879.10 KFQ95111.1 - 7.4 6.4 9.4 0.7 9.6 0.1 3.6 4 0 0 4 4 4 0 WRC Arm PF00514.23 KFQ95112.1 - 1.4e-33 113.8 5.2 3e-08 33.4 0.0 7.4 7 0 0 7 7 7 5 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KFQ95112.1 - 2.9e-07 30.9 2.4 0.19 12.3 0.0 5.1 6 0 0 6 6 6 3 HEAT-like repeat HEAT_2 PF13646.6 KFQ95112.1 - 0.00065 20.0 0.8 4 7.9 0.0 3.8 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.22 KFQ95112.1 - 0.0059 16.8 2.8 14 6.3 0.1 4.5 5 0 0 5 5 5 2 HEAT repeat Thioredoxin PF00085.20 KFQ95113.1 - 6.3e-11 42.2 0.0 1.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DUF5020 PF16412.5 KFQ95113.1 - 0.057 13.3 0.0 0.085 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5020) Med19 PF10278.9 KFQ95114.1 - 2e-72 242.9 12.7 2.2e-72 242.7 12.7 1.0 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 Connexin PF00029.19 KFQ95114.1 - 0.043 13.6 0.3 0.053 13.3 0.3 1.1 1 0 0 1 1 1 0 Connexin Zip PF02535.22 KFQ95114.1 - 0.27 10.4 0.7 0.28 10.4 0.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CLP1_P PF16575.5 KFQ95115.1 - 1.3e-36 126.2 0.0 1.7e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 KFQ95115.1 - 3.4e-31 108.1 0.0 5e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 7tm_4 PF13853.6 KFQ95116.1 - 1.1e-45 156.6 10.8 1.2e-45 156.4 10.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ95116.1 - 2.4e-29 102.5 16.6 4.8e-29 101.5 16.6 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFQ95117.1 - 5.1e-24 85.5 4.7 5.7e-24 85.3 4.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ95117.1 - 4.6e-07 29.4 6.3 6e-07 29.0 6.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1980 PF09323.10 KFQ95117.1 - 0.53 10.2 2.4 0.72 9.7 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) V-set PF07686.17 KFQ95118.1 - 8.7e-12 45.2 0.1 1.4e-11 44.6 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFQ95118.1 - 6e-09 36.4 0.1 1.2e-08 35.4 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ95118.1 - 6.2e-09 35.8 0.6 1.5e-08 34.6 0.6 1.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFQ95118.1 - 8.1e-09 35.5 0.1 1.4e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFQ95118.1 - 0.0028 18.0 0.2 0.048 14.0 0.2 2.3 1 1 0 1 1 1 1 Immunoglobulin domain Peptidase_C26 PF07722.13 KFQ95121.1 - 6.6e-21 75.1 0.0 2.9e-20 73.0 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 KFQ95121.1 - 5.1e-09 36.2 0.0 8.8e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CRAL_TRIO PF00650.20 KFQ95122.1 - 2.6e-32 111.8 0.0 3.2e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain DUF5007 PF16398.5 KFQ95122.1 - 0.13 11.9 0.1 0.28 10.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5007) YTH PF04146.15 KFQ95123.1 - 1.2e-39 135.9 0.5 1.2e-39 135.9 0.5 2.3 2 1 0 2 2 2 1 YT521-B-like domain TFIIA PF03153.13 KFQ95123.1 - 0.017 15.2 10.6 0.027 14.5 10.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 KFQ95124.1 - 1.8e-72 243.9 0.0 4.2e-72 242.7 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ95124.1 - 1.4e-39 136.0 0.0 2.2e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KFQ95124.1 - 1.6e-13 50.2 0.1 3.5e-13 49.1 0.1 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 KFQ95124.1 - 5.6e-07 29.2 0.0 1.2e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFQ95124.1 - 8.6e-05 22.0 0.1 0.00017 21.0 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFQ95124.1 - 0.00059 18.9 0.5 0.0013 17.8 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KFQ95124.1 - 0.0012 18.9 0.0 0.03 14.2 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFQ95124.1 - 0.047 13.3 0.1 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase PAX PF00292.18 KFQ95125.1 - 2e-65 218.3 0.9 3.3e-65 217.7 0.9 1.3 1 0 0 1 1 1 1 'Paired box' domain Pax2_C PF12403.8 KFQ95125.1 - 7.4e-39 132.3 6.8 7.4e-39 132.3 6.8 2.1 2 0 0 2 2 2 1 Paired-box protein 2 C terminal HTH_32 PF13565.6 KFQ95125.1 - 5e-06 27.0 0.2 0.0024 18.5 0.0 2.4 1 1 1 2 2 2 2 Homeodomain-like domain HTH_23 PF13384.6 KFQ95125.1 - 3.9e-05 23.3 0.0 8.1e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFQ95125.1 - 0.028 14.6 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_IS1 PF12759.7 KFQ95125.1 - 0.055 13.1 0.1 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 InsA C-terminal domain Homeodomain PF00046.29 KFQ95125.1 - 0.11 12.4 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 Homeodomain zf-C2H2 PF00096.26 KFQ95128.1 - 1.8e-12 47.0 11.6 6.8e-06 26.3 4.0 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ95128.1 - 3e-09 36.9 2.2 3e-09 36.9 2.2 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ95128.1 - 1.1e-08 35.2 10.0 0.00014 22.4 2.8 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KFQ95128.1 - 4.7e-06 27.1 1.4 0.00066 20.3 0.2 2.0 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KFQ95128.1 - 0.00011 22.0 4.3 0.02 14.9 0.9 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFQ95128.1 - 0.002 18.5 1.3 0.11 12.9 0.2 2.4 1 1 2 3 3 3 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFQ95128.1 - 0.0029 17.9 2.2 0.0046 17.2 2.2 1.4 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KFQ95128.1 - 0.005 17.1 2.8 0.15 12.4 0.2 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KFQ95128.1 - 0.009 16.3 1.6 0.011 16.0 1.6 1.2 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_9 PF16293.5 KFQ95128.1 - 0.037 13.9 0.2 0.8 9.6 0.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) C1_4 PF07975.12 KFQ95128.1 - 0.081 13.2 0.7 0.11 12.8 0.7 1.2 1 0 0 1 1 1 0 TFIIH C1-like domain Rad50_zn_hook PF04423.14 KFQ95128.1 - 0.084 12.7 1.0 0.2 11.5 1.0 1.8 1 1 1 2 2 2 0 Rad50 zinc hook motif DUF2225 PF09986.9 KFQ95128.1 - 0.13 12.0 0.9 0.26 11.0 0.3 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Zn-C2H2_12 PF18112.1 KFQ95128.1 - 0.17 12.4 3.5 0.49 10.9 1.8 2.4 2 1 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain DUF2054 PF10218.9 KFQ95130.1 - 9.8e-46 155.1 16.4 1.3e-45 154.7 16.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2054) APS-reductase_C PF12139.8 KFQ95130.1 - 0.023 14.9 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 Adenosine-5'-phosphosulfate reductase beta subunit DUF3369 PF11849.8 KFQ95130.1 - 0.037 14.2 0.2 0.08 13.1 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3369) EF-hand_7 PF13499.6 KFQ95131.1 - 1e-11 45.1 11.4 7.3e-07 29.5 0.6 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFQ95131.1 - 1.7e-08 33.4 0.2 1.4e-06 27.4 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KFQ95131.1 - 6.4e-06 25.7 0.4 3.9e-05 23.3 0.1 2.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 KFQ95131.1 - 8.5e-05 21.9 0.0 0.00024 20.4 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KFQ95131.1 - 0.0031 17.3 2.1 0.072 13.0 0.5 2.5 2 0 0 2 2 2 1 EF-hand domain pair Caleosin PF05042.13 KFQ95131.1 - 0.046 13.7 0.2 0.39 10.6 0.2 2.3 1 1 1 2 2 2 0 Caleosin related protein Gb3_synth PF04572.12 KFQ95131.1 - 0.071 13.3 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Alpha 1,4-glycosyltransferase conserved region M16C_assoc PF08367.11 KFQ95131.1 - 0.15 11.2 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase M16C associated Transglut_core2 PF13369.6 KFQ95132.1 - 1e-42 145.4 0.0 1.8e-42 144.6 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily YccV-like PF08755.11 KFQ95132.1 - 2.2e-29 101.9 0.2 9.1e-28 96.7 0.0 2.9 2 1 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like NO_synthase PF02898.15 KFQ95133.1 - 1.2e-190 633.2 0.0 1.7e-190 632.7 0.0 1.2 1 0 0 1 1 1 1 Nitric oxide synthase, oxygenase domain FAD_binding_1 PF00667.20 KFQ95133.1 - 4.4e-84 281.5 0.0 8.5e-84 280.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFQ95133.1 - 1.8e-30 106.1 0.6 4.5e-29 101.5 0.2 2.7 2 1 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 KFQ95133.1 - 4.6e-21 75.5 0.0 1.6e-20 73.7 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain PDZ PF00595.24 KFQ95133.1 - 9.5e-16 57.9 0.0 2.1e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFQ95133.1 - 2.8e-09 36.7 0.1 7.5e-09 35.3 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFQ95133.1 - 0.00071 19.8 0.0 0.0018 18.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Pkinase_Tyr PF07714.17 KFQ95134.1 - 5.8e-46 156.9 0.0 7.7e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ95134.1 - 1.1e-40 139.6 0.0 1.6e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain C1_1 PF00130.22 KFQ95134.1 - 1.9e-05 24.5 11.8 4.2e-05 23.3 11.8 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 KFQ95134.1 - 0.00065 19.1 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFQ95134.1 - 0.024 14.0 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFQ95134.1 - 0.025 14.2 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KFQ95134.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFQ95134.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family C1_2 PF03107.16 KFQ95134.1 - 0.33 11.3 6.5 0.78 10.1 6.5 1.6 1 0 0 1 1 1 0 C1 domain zf-RING-like PF08746.11 KFQ95134.1 - 1.4 9.3 12.1 0.15 12.4 6.9 2.1 2 0 0 2 2 2 0 RING-like domain Rep_fac_C PF08542.11 KFQ95135.1 - 2.3e-24 85.6 0.4 1.2e-23 83.3 0.1 2.3 3 0 0 3 3 2 1 Replication factor C C-terminal domain AAA PF00004.29 KFQ95135.1 - 9.3e-16 58.5 0.0 1.7e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KFQ95135.1 - 1.9e-14 53.8 0.0 5.5e-11 42.5 0.0 2.2 1 1 0 2 2 2 2 DNA polymerase III, delta subunit AAA_16 PF13191.6 KFQ95135.1 - 2.8e-06 27.8 0.0 6.8e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 KFQ95135.1 - 5.4e-06 26.5 0.0 2.1e-05 24.5 0.0 1.9 1 1 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 KFQ95135.1 - 7.5e-06 26.3 0.1 0.027 14.8 0.0 3.0 2 1 1 3 3 3 2 AAA domain AAA_24 PF13479.6 KFQ95135.1 - 8.4e-06 25.6 0.0 1.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFQ95135.1 - 1.3e-05 25.1 0.0 0.00023 21.0 0.0 2.1 1 1 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 KFQ95135.1 - 3.6e-05 24.0 0.0 8.6e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_19 PF13245.6 KFQ95135.1 - 0.00024 21.5 0.1 0.018 15.4 0.0 2.7 2 1 1 3 3 3 1 AAA domain ResIII PF04851.15 KFQ95135.1 - 0.00027 21.0 0.0 0.073 13.1 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit RuvB_N PF05496.12 KFQ95135.1 - 0.00034 20.4 0.0 0.00081 19.2 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KFQ95135.1 - 0.0005 20.1 0.1 0.0035 17.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PhoH PF02562.16 KFQ95135.1 - 0.00088 18.8 0.3 0.14 11.6 0.0 3.0 2 1 0 3 3 3 1 PhoH-like protein DUF815 PF05673.13 KFQ95135.1 - 0.001 18.3 0.0 0.0019 17.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 KFQ95135.1 - 0.001 18.8 0.0 0.018 14.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KFQ95135.1 - 0.0015 18.6 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 KFQ95135.1 - 0.0017 18.2 0.0 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DEAD PF00270.29 KFQ95135.1 - 0.0017 18.2 0.0 0.04 13.7 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase TniB PF05621.11 KFQ95135.1 - 0.0029 17.0 0.0 0.061 12.7 0.0 2.1 2 0 0 2 2 2 1 Bacterial TniB protein TIP49 PF06068.13 KFQ95135.1 - 0.014 14.6 0.0 0.032 13.5 0.0 1.5 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_7 PF12775.7 KFQ95135.1 - 0.014 14.9 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KFQ95135.1 - 0.018 14.6 0.0 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KFQ95135.1 - 0.018 14.8 0.0 0.12 12.0 0.0 2.1 1 1 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KFQ95135.1 - 0.048 13.0 0.0 0.75 9.1 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KFQ95135.1 - 0.099 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SNF2_N PF00176.23 KFQ95135.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain Hydantoinase_B PF02538.14 KFQ95135.1 - 0.15 10.5 0.0 0.23 9.8 0.0 1.2 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase Thioredoxin_6 PF13848.6 KFQ95135.1 - 0.17 11.8 0.0 0.68 9.8 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like domain DTC PF18102.1 KFQ95136.1 - 2.3e-60 202.6 0.0 3.4e-60 202.0 0.0 1.3 1 0 0 1 1 1 1 Deltex C-terminal domain zf-C3HC4 PF00097.25 KFQ95136.1 - 7.4e-06 25.7 1.0 1.8e-05 24.5 1.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ95136.1 - 1.3e-05 25.5 1.0 6.8e-05 23.1 1.0 2.2 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFQ95136.1 - 2.1e-05 24.4 0.3 5.6e-05 23.1 0.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KFQ95136.1 - 3.2e-05 24.1 1.6 0.00013 22.2 0.6 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFQ95136.1 - 0.00023 21.0 0.8 0.00051 19.9 0.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KFQ95136.1 - 0.0011 18.6 1.3 0.61 9.9 0.1 2.6 2 0 0 2 2 2 2 RING-like zinc finger zf-ANAPC11 PF12861.7 KFQ95136.1 - 0.0045 17.0 1.8 0.015 15.3 1.0 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KFQ95136.1 - 0.0086 15.9 2.8 0.47 10.3 0.4 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-LITAF-like PF10601.9 KFQ95136.1 - 0.034 14.4 0.9 0.034 14.4 0.9 2.3 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain zf-UDP PF14569.6 KFQ95136.1 - 0.037 14.1 0.8 0.071 13.2 0.1 1.8 2 0 0 2 2 2 0 Zinc-binding RING-finger PHD PF00628.29 KFQ95136.1 - 0.12 12.2 0.3 0.12 12.2 0.3 1.9 2 0 0 2 2 2 0 PHD-finger FANCL_C PF11793.8 KFQ95136.1 - 0.37 11.0 2.4 1.2 9.4 2.4 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 KFQ95136.1 - 0.77 10.0 3.4 0.59 10.3 0.7 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING ADK_lid PF05191.14 KFQ95136.1 - 1.6 8.7 8.7 9.2 6.4 0.1 4.0 4 0 0 4 4 4 0 Adenylate kinase, active site lid ADAM17_MPD PF16698.5 KFQ95138.1 - 4.9 7.6 18.4 1.8 9.0 1.6 3.3 1 1 2 3 3 3 0 Membrane-proximal domain, switch, for ADAM17 DUF1030 PF06270.11 KFQ95139.1 - 0.36 10.6 3.3 2.8 7.8 0.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1030) RRM_1 PF00076.22 KFQ95140.1 - 1.2e-10 41.0 0.0 4.9e-10 39.1 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GAS2 PF02187.17 KFQ95141.1 - 4.8e-32 109.9 0.1 8.7e-32 109.0 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.31 KFQ95141.1 - 3e-14 53.1 0.5 4.9e-14 52.4 0.5 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Adaptin_N PF01602.20 KFQ95142.1 - 1.1e-164 548.9 15.1 1.4e-164 548.5 15.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KFQ95142.1 - 8.9e-69 230.7 12.7 1.2e-66 223.7 1.3 3.6 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 KFQ95142.1 - 2.4e-36 124.2 0.1 6.3e-36 122.9 0.1 1.8 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 KFQ95142.1 - 8.7e-23 80.5 3.9 1.4e-08 35.0 0.0 6.1 3 2 4 7 7 7 6 HEAT repeats HEAT PF02985.22 KFQ95142.1 - 2.7e-13 48.9 8.6 0.008 16.4 0.1 7.4 7 0 0 7 7 7 3 HEAT repeat Alpha_adaptinC2 PF02883.20 KFQ95142.1 - 7.9e-10 39.0 0.3 7.9e-10 39.0 0.3 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain Cnd3 PF12719.7 KFQ95142.1 - 1.8e-09 37.2 4.2 1.1e-05 24.8 0.3 2.7 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 KFQ95142.1 - 6.1e-07 29.3 4.6 0.019 15.0 0.0 5.6 6 0 0 6 6 5 2 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KFQ95142.1 - 1.6e-05 25.1 6.9 0.047 13.9 0.0 5.2 2 2 1 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KFQ95142.1 - 8.7e-05 22.2 2.0 0.72 9.4 0.1 4.1 2 2 1 3 3 3 2 CLASP N terminal Arm_2 PF04826.13 KFQ95142.1 - 0.0071 15.8 0.2 0.028 13.9 0.0 2.1 2 0 0 2 2 2 1 Armadillo-like UNC45-central PF11701.8 KFQ95142.1 - 0.011 15.7 0.5 1.4 8.8 0.0 3.5 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central Alpha_adaptin_C PF02296.16 KFQ95142.1 - 0.018 15.2 0.2 0.085 13.0 0.0 2.3 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain HEAT_EZ PF13513.6 KFQ95142.1 - 0.059 13.9 7.6 12 6.6 0.0 5.9 7 0 0 7 7 7 0 HEAT-like repeat Cohesin_HEAT PF12765.7 KFQ95142.1 - 0.093 13.1 0.1 83 3.6 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Sec7_N PF12783.7 KFQ95142.1 - 0.9 9.4 7.9 0.27 11.1 0.4 3.5 3 1 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal NIPSNAP PF07978.13 KFQ95143.1 - 1.1e-37 128.4 0.4 8.2e-34 115.9 0.4 2.2 2 0 0 2 2 2 2 NIPSNAP ERM PF00769.19 KFQ95144.1 - 3.5e-32 112.2 50.3 3.5e-32 112.2 50.3 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_M PF00373.18 KFQ95144.1 - 3e-27 95.4 0.9 3e-27 95.4 0.9 3.0 2 1 1 3 3 3 1 FERM central domain FERM_C PF09380.10 KFQ95144.1 - 5.7e-25 87.5 0.1 3e-24 85.2 0.0 2.2 3 0 0 3 3 3 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KFQ95144.1 - 1.2e-09 38.0 0.1 4.7e-09 36.1 0.1 2.1 1 0 0 1 1 1 1 FERM N-terminal domain EF-hand_1 PF00036.32 KFQ95145.1 - 0.0013 18.1 0.2 0.042 13.4 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KFQ95145.1 - 0.0031 17.3 1.9 1.1 9.2 0.1 2.6 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFQ95145.1 - 0.0057 16.1 0.5 0.15 11.6 0.1 2.3 2 0 0 2 2 2 1 EF hand DUF3271 PF11675.8 KFQ95145.1 - 0.033 13.4 0.0 0.041 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) EF-hand_6 PF13405.6 KFQ95145.1 - 0.047 13.6 0.4 1.8 8.7 0.0 2.6 2 1 0 2 2 2 0 EF-hand domain U79_P34 PF03064.16 KFQ95145.1 - 0.094 12.1 0.1 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 zf-CCCH PF00642.24 KFQ95146.1 - 9e-09 35.0 2.4 1.4e-08 34.4 2.4 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KFQ95146.1 - 5.1e-08 32.5 2.9 9e-08 31.7 2.9 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-U1 PF06220.12 KFQ95146.1 - 2.2e-07 30.5 4.2 3.9e-07 29.7 4.2 1.4 1 0 0 1 1 1 1 U1 zinc finger zf_CCCH_4 PF18345.1 KFQ95146.1 - 1.1e-06 28.5 4.3 1.8e-06 27.8 4.3 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 KFQ95146.1 - 0.0016 18.8 2.9 0.0028 18.1 2.9 1.4 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger DUF4239 PF14023.6 KFQ95146.1 - 0.25 11.0 0.1 0.74 9.5 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) zf-C2H2_jaz PF12171.8 KFQ95146.1 - 1.1 9.6 6.9 6.7 7.1 6.9 2.1 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding UCR_UQCRX_QCR9 PF05365.12 KFQ95147.1 - 2e-23 82.1 0.0 2.4e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Myotub-related PF06602.14 KFQ95148.1 - 7e-139 462.6 0.1 9.8e-139 462.2 0.1 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 KFQ95148.1 - 0.00064 19.4 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFQ95148.1 - 0.0027 17.5 0.0 0.0059 16.4 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFQ95148.1 - 0.0036 17.3 0.0 0.0063 16.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KFQ95148.1 - 0.13 11.9 0.0 0.35 10.4 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family Acyl-CoA_dh_1 PF00441.24 KFQ95149.1 - 9.2e-31 107.1 0.6 9.2e-31 107.1 0.6 2.0 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 KFQ95149.1 - 3.1e-25 88.9 0.0 7.3e-25 87.7 0.0 1.6 2 0 0 2 2 2 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 KFQ95149.1 - 8.3e-15 54.8 0.0 1.5e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFQ95149.1 - 6.1e-10 39.5 1.8 3.5e-09 37.0 0.0 2.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HORMA PF02301.18 KFQ95150.1 - 2.2e-49 167.9 0.0 4.2e-47 160.5 0.0 2.1 1 1 0 1 1 1 1 HORMA domain HTH_micro PF17007.5 KFQ95150.1 - 0.055 12.3 0.1 0.067 12.0 0.1 1.1 1 0 0 1 1 1 0 HTH-like LIF_OSM PF01291.17 KFQ95151.1 - 2.9e-33 115.3 2.4 3.2e-33 115.2 2.4 1.0 1 0 0 1 1 1 1 LIF / OSM family ACT_7 PF13840.6 KFQ95152.1 - 1.4e-33 114.5 0.1 2.2e-17 62.6 0.1 2.3 2 0 0 2 2 2 2 ACT domain Castor1_N PF18700.1 KFQ95152.1 - 3.2e-32 110.2 0.8 2.7e-30 104.0 0.1 2.6 3 0 0 3 3 3 2 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain RabGAP-TBC PF00566.18 KFQ95153.1 - 2.9e-54 184.0 0.0 4.3e-54 183.4 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain LRRCT PF01463.24 KFQ95153.1 - 0.24 12.0 2.1 32 5.4 0.1 3.4 3 0 0 3 3 3 0 Leucine rich repeat C-terminal domain KASH_CCD PF14662.6 KFQ95154.1 - 0.0053 16.6 11.9 0.0053 16.6 11.9 4.0 1 1 2 3 3 3 1 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 KFQ95154.1 - 0.018 15.1 14.8 0.018 15.1 14.8 5.4 3 1 3 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 KFQ95154.1 - 0.027 13.8 73.4 0.12 11.7 21.0 4.5 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding HOOK PF05622.12 KFQ95154.1 - 1.1 7.3 59.7 0.068 11.3 53.8 1.9 2 0 0 2 2 2 0 HOOK protein DUF4279 PF14106.6 KFQ95154.1 - 2.7 8.2 6.6 1.9 8.7 0.3 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4279) BLOC1_2 PF10046.9 KFQ95154.1 - 3.2 8.1 47.4 0.35 11.2 5.7 6.0 2 1 3 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SKA2 PF16740.5 KFQ95154.1 - 9 6.1 49.5 0.03 14.1 5.1 5.0 1 1 3 4 4 4 0 Spindle and kinetochore-associated protein 2 zf-RING_2 PF13639.6 KFQ95155.1 - 1.9e-12 47.3 7.9 4e-12 46.3 7.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFQ95155.1 - 1.4e-10 40.7 3.3 3.3e-10 39.5 3.3 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFQ95155.1 - 5.7e-09 35.7 7.9 1.1e-08 34.8 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ95155.1 - 1.7e-07 31.0 4.8 3.5e-07 30.0 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFQ95155.1 - 4.3e-07 30.1 8.9 3.4e-06 27.2 8.9 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFQ95155.1 - 1.9e-06 27.7 3.9 3.5e-06 26.9 3.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFQ95155.1 - 6.3e-06 26.1 2.0 6.3e-06 26.1 2.0 1.8 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFQ95155.1 - 4.1e-05 23.3 4.5 0.0001 22.1 4.5 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFQ95155.1 - 8.1e-05 22.4 2.8 0.00015 21.5 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 KFQ95155.1 - 0.0091 16.0 2.2 0.024 14.7 2.2 1.7 1 0 0 1 1 1 1 Zinc-finger FtsL PF04999.13 KFQ95155.1 - 0.0093 15.9 0.7 0.02 14.9 0.7 1.5 1 0 0 1 1 1 1 Cell division protein FtsL ZNRF_3_ecto PF18212.1 KFQ95155.1 - 0.011 15.7 0.2 0.018 15.1 0.2 1.4 1 0 0 1 1 1 0 ZNRF-3 Ectodomain zf-ANAPC11 PF12861.7 KFQ95155.1 - 0.046 13.8 4.4 0.12 12.5 4.4 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFQ95155.1 - 1.5 8.5 8.7 3.8 7.2 8.7 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type CRAL_TRIO PF00650.20 KFQ95156.1 - 6.9e-41 139.6 0.0 9.5e-41 139.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 KFQ95156.1 - 6.9e-09 36.3 0.8 9.4e-06 26.2 0.1 2.5 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking CRAL_TRIO_2 PF13716.6 KFQ95156.1 - 4e-06 27.0 0.0 8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFQ95156.1 - 0.0029 17.8 0.2 0.01 16.0 0.2 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Gal-3-0_sulfotr PF06990.11 KFQ95157.1 - 8.7e-154 512.2 2.2 9.7e-154 512.1 2.2 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_3 PF13469.6 KFQ95157.1 - 0.029 14.8 0.2 0.079 13.3 0.1 1.8 2 0 0 2 2 2 0 Sulfotransferase family Pescadillo_N PF06732.11 KFQ95158.1 - 3.2e-125 417.2 1.1 3.2e-125 417.2 1.1 2.1 3 0 0 3 3 3 1 Pescadillo N-terminus BRCT_2 PF16589.5 KFQ95158.1 - 3.5e-08 33.7 0.0 7.4e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DNA_pol_phi PF04931.13 KFQ95158.1 - 0.15 10.2 22.6 0.22 9.6 22.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 KFQ95158.1 - 0.42 8.8 22.9 0.9 7.8 22.9 1.5 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.16 KFQ95158.1 - 0.6 9.3 10.6 2.8 7.1 9.3 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Roughex PF06020.11 KFQ95158.1 - 3.9 6.5 12.5 6.8 5.7 12.5 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Cobalamin_bind PF01122.19 KFQ95159.1 - 7e-58 196.0 0.0 7.7e-58 195.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic cobalamin-binding protein TPT PF03151.16 KFQ95160.1 - 4.1e-09 36.2 0.0 4.8e-09 36.0 0.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFQ95160.1 - 2.8e-06 27.5 1.0 5.1e-06 26.7 1.0 1.4 1 1 0 1 1 1 1 EamA-like transporter family Bax1-I PF01027.20 KFQ95160.1 - 0.057 13.2 4.2 0.071 12.9 4.2 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 PH PF00169.29 KFQ95161.1 - 3e-05 24.5 0.0 0.0001 22.8 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 KFQ95161.1 - 3.8e-05 23.9 0.0 0.00011 22.4 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Oxysterol_BP PF01237.18 KFQ95161.1 - 0.00013 21.0 0.2 0.00013 21.0 0.2 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein Syntaxin-6_N PF09177.11 KFQ95161.1 - 0.0046 17.5 10.4 0.037 14.6 1.0 3.5 2 1 2 4 4 4 1 Syntaxin 6, N-terminal PH_11 PF15413.6 KFQ95161.1 - 0.0073 16.7 0.1 0.027 14.9 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 KFQ95161.1 - 0.012 15.9 0.0 0.029 14.7 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain PH_13 PF16652.5 KFQ95161.1 - 0.012 15.4 0.4 0.048 13.5 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain MbeD_MobD PF04899.12 KFQ95161.1 - 0.091 12.9 2.2 0.26 11.4 0.4 2.3 2 0 0 2 2 2 0 MbeD/MobD like MerR-DNA-bind PF09278.11 KFQ95161.1 - 0.59 10.7 6.1 0.55 10.8 3.2 2.3 2 0 0 2 2 2 0 MerR, DNA binding DUF2205 PF10224.9 KFQ95161.1 - 5.7 7.0 8.5 2.1 8.4 0.1 3.0 2 1 1 3 3 3 0 Short coiled-coil protein Oxysterol_BP PF01237.18 KFQ95162.1 - 7.7e-31 107.3 0.4 8.5e-31 107.1 0.4 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Pro_dh PF01619.18 KFQ95164.1 - 7.5e-65 219.4 0.1 3.8e-63 213.8 0.1 2.0 1 1 0 1 1 1 1 Proline dehydrogenase HrpB2 PF09487.10 KFQ95164.1 - 0.047 14.1 1.1 0.07 13.6 0.1 1.7 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) Laminin_EGF PF00053.24 KFQ95165.1 - 4e-23 81.3 175.5 0.0043 17.2 13.7 11.0 2 1 8 10 10 10 9 Laminin EGF domain EGF_2 PF07974.13 KFQ95165.1 - 0.005 17.2 11.3 0.005 17.2 11.3 16.8 12 3 3 15 15 15 7 EGF-like domain DSL PF01414.19 KFQ95165.1 - 0.0054 17.0 14.1 0.0054 17.0 14.1 10.3 8 1 3 11 11 11 4 Delta serrate ligand Tweety PF04906.13 KFQ95165.1 - 0.063 11.9 2.7 0.11 11.2 2.7 1.3 1 0 0 1 1 1 0 Tweety DGCR6 PF07324.11 KFQ95166.1 - 1.1e-51 175.3 6.3 1.2e-51 175.1 6.3 1.0 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein AA_permease_2 PF13520.6 KFQ95167.1 - 1.2e-44 152.9 40.0 1.2e-44 152.9 40.0 2.0 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 KFQ95167.1 - 2.3e-38 132.0 42.2 3.2e-38 131.5 33.3 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease_C PF13906.6 KFQ95167.1 - 8.1e-21 73.8 8.5 8.1e-21 73.8 8.5 4.1 4 0 0 4 4 4 1 C-terminus of AA_permease LRR_6 PF13516.6 KFQ95168.1 - 1.3e-25 87.2 5.2 0.00012 21.9 0.0 7.0 7 0 0 7 7 7 6 Leucine Rich repeat LRR_1 PF00560.33 KFQ95168.1 - 3.6e-08 32.8 0.0 15 6.6 0.0 6.0 5 2 1 6 6 6 2 Leucine Rich Repeat LRR_4 PF12799.7 KFQ95168.1 - 1.7e-05 25.1 1.8 0.031 14.7 0.1 4.1 2 1 2 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFQ95168.1 - 0.0096 15.7 5.7 8.9 6.2 0.1 4.8 1 1 3 4 4 4 3 Leucine rich repeat P2X_receptor PF00864.19 KFQ95169.1 - 1.1e-92 310.9 0.1 1.4e-92 310.7 0.1 1.0 1 0 0 1 1 1 1 ATP P2X receptor Transmemb_17 PF09799.9 KFQ95170.1 - 3.9e-19 69.2 4.3 4.4e-19 69.1 4.3 1.0 1 0 0 1 1 1 1 Predicted membrane protein FIIND PF13553.6 KFQ95171.1 - 2.9e-86 289.0 0.2 3.8e-86 288.6 0.2 1.2 1 0 0 1 1 1 1 Function to find CARD PF00619.21 KFQ95171.1 - 5.9e-14 51.9 2.7 9.2e-14 51.2 2.7 1.3 1 0 0 1 1 1 1 Caspase recruitment domain HSR PF03172.13 KFQ95171.1 - 0.0078 16.4 0.1 0.018 15.2 0.1 1.6 1 0 0 1 1 1 1 HSR domain Connexin PF00029.19 KFQ95172.1 - 1.3e-74 250.9 0.3 1.5e-74 250.7 0.3 1.1 1 0 0 1 1 1 1 Connexin zf-H2C2_5 PF13909.6 KFQ95173.1 - 2.8e-14 52.5 30.2 2.2e-06 27.3 4.2 27.5 29 0 0 29 29 29 15 C2H2-type zinc-finger domain zf_C2H2_ZHX PF18387.1 KFQ95173.1 - 9.6e-10 38.0 148.5 0.0078 15.8 1.4 26.2 25 3 4 29 29 29 14 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 KFQ95173.1 - 0.007 16.8 6.6 0.007 16.8 6.6 28.2 34 0 0 34 34 34 9 Zinc-finger double domain FKBP_N_2 PF18023.1 KFQ95173.1 - 0.94 9.6 7.1 2.7 8.1 0.2 3.1 2 0 0 2 2 2 0 BDBT FKBP like N-terminal Aminotran_5 PF00266.19 KFQ95174.1 - 1.2e-53 182.4 0.0 1.6e-53 182.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_3 PF00202.21 KFQ95174.1 - 0.1 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III EamA PF00892.20 KFQ95175.1 - 3.5e-15 56.4 30.8 9.3e-08 32.3 7.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family Carboxyl_trans PF01039.22 KFQ95176.1 - 2.2e-190 633.5 0.0 2.6e-190 633.3 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 KFQ95176.1 - 0.021 14.3 1.2 0.29 10.6 0.0 2.7 2 1 1 3 3 3 0 Malonate decarboxylase gamma subunit (MdcE) MSL2-CXC PF16682.5 KFQ95177.1 - 2.9e-19 68.9 20.3 5.5e-19 68.0 20.3 1.5 1 0 0 1 1 1 1 CXC domain of E3 ubiquitin-protein ligase MSL2 EF-hand_13 PF17958.1 KFQ95178.1 - 2.6e-40 136.1 0.1 4.3e-39 132.2 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 KFQ95178.1 - 4.6e-21 75.0 5.4 4e-20 72.1 0.6 3.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 KFQ95178.1 - 1.2e-05 24.5 0.2 0.0008 18.8 0.0 3.2 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 KFQ95178.1 - 0.00022 21.0 0.1 1 9.2 0.0 4.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KFQ95178.1 - 0.00026 20.7 2.1 0.036 14.0 0.0 4.2 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 KFQ95178.1 - 0.00086 18.7 1.7 0.065 12.8 0.1 4.0 4 0 0 4 4 4 1 EF hand SPARC_Ca_bdg PF10591.9 KFQ95178.1 - 0.018 15.4 1.4 5.8 7.3 0.3 2.8 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DBR1 PF05011.13 KFQ95179.1 - 4.4e-36 124.4 0.2 8e-36 123.5 0.2 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KFQ95179.1 - 6.9e-05 23.4 0.3 0.00012 22.7 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Adaptin_binding PF10199.9 KFQ95179.1 - 0.25 12.0 3.7 2.6 8.7 3.7 2.5 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Arm PF00514.23 KFQ95180.1 - 1e-17 63.5 22.4 0.00019 21.4 0.2 11.3 12 0 0 12 12 12 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KFQ95180.1 - 1.7e-08 34.7 3.9 0.0096 16.4 0.1 6.4 7 1 1 8 8 8 2 HEAT-like repeat HEAT PF02985.22 KFQ95180.1 - 6e-07 29.2 17.7 0.032 14.5 0.1 8.2 9 0 0 9 9 9 2 HEAT repeat V-ATPase_H_C PF11698.8 KFQ95180.1 - 9.3e-07 29.0 9.7 0.17 12.0 0.0 5.8 4 2 2 6 6 6 3 V-ATPase subunit H Uso1_p115_head PF04869.14 KFQ95180.1 - 0.0013 17.9 2.8 0.4 9.8 0.4 3.8 3 1 0 3 3 3 1 Uso1 / p115 like vesicle tethering protein, head region ParcG PF10274.9 KFQ95180.1 - 0.056 13.6 3.3 0.86 9.7 0.3 3.4 2 1 0 3 3 3 0 Parkin co-regulated protein Cnd1 PF12717.7 KFQ95180.1 - 0.085 12.9 15.9 0.51 10.4 0.9 4.4 2 2 2 5 5 5 0 non-SMC mitotic condensation complex subunit 1 RasGEF_N_2 PF14663.6 KFQ95180.1 - 0.21 12.0 4.6 11 6.4 0.1 4.3 3 1 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RTTN_N PF14726.6 KFQ95180.1 - 3.6 8.5 8.6 55 4.6 0.1 4.8 2 1 2 4 4 4 0 Rotatin, an armadillo repeat protein, centriole functioning DUF3361 PF11841.8 KFQ95180.1 - 3.9 7.4 18.5 4.1 7.3 2.4 4.5 2 1 2 4 4 4 0 Domain of unknown function (DUF3361) Thioredoxin PF00085.20 KFQ95181.1 - 6.1e-06 26.2 0.0 6.8e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Vps8 PF12816.7 KFQ95182.1 - 2.3e-59 200.3 9.1 1.7e-57 194.1 0.9 3.3 3 0 0 3 3 3 2 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KFQ95182.1 - 1.4e-07 31.5 7.5 7.4e-05 22.7 0.6 3.7 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_11 PF17123.5 KFQ95182.1 - 3.1e-05 23.6 5.0 9.6e-05 22.0 5.0 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KFQ95182.1 - 0.0073 16.3 5.6 0.023 14.7 5.6 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFQ95182.1 - 0.02 15.2 8.4 0.057 13.8 8.4 1.9 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.29 KFQ95182.1 - 0.27 11.2 9.0 0.54 10.2 9.0 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.6 KFQ95182.1 - 3.4 7.7 8.9 10 6.2 8.9 1.9 1 0 0 1 1 1 0 zinc-RING finger domain UPF0524 PF15823.5 KFQ95183.1 - 8.4e-85 284.0 4.9 9.4e-85 283.8 4.9 1.0 1 0 0 1 1 1 1 UPF0524 of C3orf70 ECH_1 PF00378.20 KFQ95184.1 - 1.5e-36 126.0 0.2 1.6e-36 125.9 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFQ95184.1 - 7.2e-27 94.7 0.1 1e-26 94.3 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KFQ95184.1 - 0.00024 21.1 0.0 0.31 11.0 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S49 SeleniumBinding PF11524.8 KFQ95184.1 - 0.13 12.7 0.1 0.29 11.6 0.1 1.6 1 0 0 1 1 1 0 Selenium binding protein Pkinase_Tyr PF07714.17 KFQ95185.1 - 2.8e-64 216.9 0.0 4.3e-64 216.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ95185.1 - 2.6e-59 200.7 0.0 4.8e-59 199.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KFQ95185.1 - 0.00098 18.0 0.0 0.0029 16.4 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase DUF737 PF05300.11 KFQ95185.1 - 0.023 15.1 0.4 0.023 15.1 0.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF737) APH PF01636.23 KFQ95185.1 - 0.073 13.0 0.0 2 8.3 0.0 2.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family SNARE_assoc PF09335.11 KFQ95187.1 - 2.3e-17 63.6 5.9 2.3e-17 63.6 5.9 1.4 2 0 0 2 2 2 1 SNARE associated Golgi protein Lipase PF00151.19 KFQ95188.1 - 4.8e-84 282.5 0.0 6.5e-84 282.1 0.0 1.1 1 0 0 1 1 1 1 Lipase Apc13p PF05839.11 KFQ95189.1 - 3.6e-20 71.9 0.3 5e-20 71.5 0.3 1.2 1 0 0 1 1 1 1 Apc13p protein CEP63 PF17045.5 KFQ95190.1 - 5.5e-109 364.2 57.6 5.5e-109 364.2 57.6 4.6 3 1 2 5 5 5 2 Centrosomal protein of 63 kDa Tup_N PF08581.10 KFQ95190.1 - 0.012 15.9 8.2 0.012 15.9 8.2 8.1 4 2 5 9 9 9 0 Tup N-terminal DASH_Dam1 PF08653.10 KFQ95190.1 - 6.2 6.7 7.2 21 5.0 0.1 4.9 4 0 0 4 4 4 0 DASH complex subunit Dam1 Pkinase_Tyr PF07714.17 KFQ95191.1 - 2.9e-100 334.8 0.0 3.4e-100 334.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ95191.1 - 1.2e-50 172.3 0.0 1.5e-50 172.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.6 KFQ95191.1 - 1.3e-13 51.6 1.0 2.4e-13 50.8 1.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Haspin_kinase PF12330.8 KFQ95191.1 - 0.0044 16.0 0.0 0.007 15.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain ABC1 PF03109.16 KFQ95191.1 - 0.011 15.9 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Kdo PF06293.14 KFQ95191.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFQ95191.1 - 0.15 10.8 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Gb3_synth PF04572.12 KFQ95192.1 - 1.1e-44 151.7 0.4 1.7e-44 151.1 0.4 1.3 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.15 KFQ95192.1 - 1.6e-19 70.4 0.0 4.5e-19 68.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KFQ95192.1 - 0.023 14.1 0.0 0.067 12.6 0.0 1.7 1 1 0 1 1 1 0 Capsular polysaccharide synthesis protein PMP22_Claudin PF00822.20 KFQ95193.1 - 3.2e-31 108.5 14.4 4.2e-31 108.1 14.4 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFQ95193.1 - 1.6e-12 47.6 15.7 3.5e-11 43.2 15.7 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Trp_oprn_chp PF09534.10 KFQ95193.1 - 0.0052 16.6 1.3 0.1 12.4 1.2 2.4 1 1 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Amastin PF07344.11 KFQ95193.1 - 0.56 10.0 11.5 0.38 10.6 9.5 1.7 1 1 0 1 1 1 0 Amastin surface glycoprotein Phage_holin_3_6 PF07332.11 KFQ95193.1 - 3.1 7.9 20.8 0.078 13.0 5.4 2.5 1 1 2 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF308 PF03729.13 KFQ95193.1 - 3.4 8.1 23.9 0.16 12.3 8.3 3.0 2 1 2 4 4 4 0 Short repeat of unknown function (DUF308) Phage_holin_5_2 PF16079.5 KFQ95193.1 - 9.3 6.7 16.9 32 4.9 6.7 3.5 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V HMG_box PF00505.19 KFQ95194.1 - 1.9e-25 89.1 7.8 8.2e-25 87.0 6.1 2.4 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFQ95194.1 - 1.7e-09 38.2 2.6 4e-09 36.9 2.6 1.6 1 1 0 1 1 1 1 HMG-box domain SOXp PF12336.8 KFQ95194.1 - 3.8e-07 31.1 1.2 5.2e-06 27.4 1.2 2.4 1 1 0 1 1 1 1 SOX transcription factor Crystall PF00030.19 KFQ95195.1 - 5.6e-60 199.5 1.7 2.4e-29 101.3 0.1 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin IL4_i_Ig PF18258.1 KFQ95195.1 - 8.3e-08 32.3 0.4 0.021 15.0 0.0 2.9 2 1 0 2 2 2 2 Interleukin-4 inducing immunoglobulin-binding domain Crystall_3 PF08964.10 KFQ95195.1 - 0.00041 20.5 0.1 13 6.0 0.1 3.2 3 0 0 3 3 3 3 Beta/Gamma crystallin Inhibitor_I36 PF03995.13 KFQ95195.1 - 0.022 14.7 3.5 17 5.4 0.2 3.7 2 1 1 4 4 4 0 Peptidase inhibitor family I36 LPD18 PF18832.1 KFQ95195.1 - 0.052 13.6 0.1 12 6.0 0.0 2.2 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 18 TBCC PF07986.12 KFQ95196.1 - 1.1e-37 128.4 0.6 2.7e-37 127.1 0.3 1.8 2 0 0 2 2 2 1 Tubulin binding cofactor C CAP_C PF08603.11 KFQ95196.1 - 1.7e-05 24.5 2.0 3.9e-05 23.3 2.0 1.5 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal DnaJ_C PF01556.18 KFQ95197.1 - 7.2e-38 130.0 0.1 1.2e-37 129.2 0.1 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFQ95197.1 - 1.5e-26 92.3 0.5 2.2e-26 91.8 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain MHC_I_3 PF16497.5 KFQ95198.1 - 1.7e-06 27.7 0.0 2.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 MHC-I family domain PFK PF00365.20 KFQ95199.1 - 1.2e-196 651.5 5.2 1.1e-100 336.6 0.6 2.1 2 0 0 2 2 2 2 Phosphofructokinase LRR_4 PF12799.7 KFQ95200.1 - 1e-08 35.3 13.2 3.7e-05 24.0 3.5 3.5 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFQ95200.1 - 4e-07 29.7 0.3 9.7e-07 28.5 0.3 1.6 1 1 0 1 1 1 1 Leucine-rich repeat SART-1 PF03343.13 KFQ95200.1 - 1.5e-05 23.8 0.2 2.1e-05 23.3 0.2 1.2 1 0 0 1 1 1 1 SART-1 family LRR_8 PF13855.6 KFQ95200.1 - 0.00012 21.8 3.9 0.0042 16.8 3.4 2.9 1 1 1 2 2 2 2 Leucine rich repeat RRM_1 PF00076.22 KFQ95201.1 - 5.1e-22 77.5 0.0 7.2e-22 77.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFQ95201.1 - 0.02 14.7 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_3 PF08777.11 KFQ95201.1 - 0.026 14.6 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif Apt1 PF10351.9 KFQ95201.1 - 0.13 11.1 13.0 0.15 10.9 13.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 KFQ95201.1 - 0.64 8.7 4.6 0.68 8.6 4.6 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 KFQ95201.1 - 0.94 8.2 6.9 1.1 8.0 6.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 KH_1 PF00013.29 KFQ95202.1 - 6.2e-57 189.3 12.2 1.6e-15 56.6 0.2 4.3 4 0 0 4 4 4 4 KH domain KH_2 PF07650.17 KFQ95202.1 - 8e-17 60.8 8.1 0.00042 20.1 0.1 4.8 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 KFQ95202.1 - 2.8e-15 56.0 4.4 0.0013 18.6 0.1 5.0 5 0 0 5 5 5 4 KH domain RRM_1 PF00076.22 KFQ95202.1 - 3.4e-07 30.0 0.0 7.8e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_5 PF13184.6 KFQ95202.1 - 3.8e-07 30.1 3.9 0.4 10.8 0.1 4.5 4 0 0 4 4 4 3 NusA-like KH domain MOEP19 PF16005.5 KFQ95202.1 - 1.1e-05 25.4 0.1 0.13 12.3 0.0 3.9 4 0 0 4 4 4 1 KH-like RNA-binding domain SLS PF14611.6 KFQ95202.1 - 0.85 9.4 5.0 9.3 6.0 0.1 3.8 4 1 1 5 5 5 0 Mitochondrial inner-membrane-bound regulator Peptidase_C48 PF02902.19 KFQ95203.1 - 1.2e-43 149.5 1.2 1.6e-43 149.0 1.2 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.13 KFQ95203.1 - 0.0031 16.3 0.0 0.23 10.1 0.0 2.1 2 0 0 2 2 2 2 Vaccinia virus I7 processing peptidase Angiomotin_C PF12240.8 KFQ95204.1 - 1.2e-95 318.9 10.5 1.2e-95 318.9 10.5 4.2 2 1 2 4 4 4 1 Angiomotin C terminal YqhG PF11079.8 KFQ95204.1 - 0.078 11.9 1.9 0.16 10.9 1.9 1.4 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function Pkinase_Tyr PF07714.17 KFQ95205.1 - 5.2e-81 271.7 0.0 7e-81 271.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ95205.1 - 2.8e-27 95.7 0.0 4.4e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WIF PF02019.18 KFQ95205.1 - 5e-09 35.9 0.5 5e-09 35.9 0.5 1.7 2 0 0 2 2 2 1 WIF domain SID-1_RNA_chan PF13965.6 KFQ95205.1 - 0.029 12.8 0.7 0.043 12.2 0.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Gal-3-0_sulfotr PF06990.11 KFQ95206.1 - 6.8e-120 400.6 0.4 7.6e-120 400.5 0.4 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 KFQ95206.1 - 0.00028 20.9 0.1 0.00082 19.3 0.1 2.1 1 1 0 1 1 1 1 Sulfotransferase family MIP PF00230.20 KFQ95207.1 - 1.1e-08 35.1 5.5 1.3e-08 34.9 5.5 1.3 1 0 0 1 1 1 1 Major intrinsic protein Pkinase PF00069.25 KFQ95208.1 - 5.9e-74 248.8 0.0 8.3e-74 248.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ95208.1 - 1.5e-47 162.1 0.0 2.6e-47 161.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KFQ95208.1 - 3.8e-25 88.0 0.0 9e-25 86.8 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KFQ95208.1 - 3.5e-08 33.1 0.1 0.00036 20.0 0.0 2.4 1 1 1 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KFQ95208.1 - 3.3e-06 26.2 0.0 6.8e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFQ95208.1 - 0.0036 17.3 0.0 0.046 13.6 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFQ95208.1 - 0.0052 15.8 1.2 0.03 13.3 1.2 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFQ95208.1 - 0.029 13.7 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PIG-X PF08320.12 KFQ95209.1 - 2e-41 142.2 0.0 2.3e-41 142.0 0.0 1.0 1 0 0 1 1 1 1 PIG-X / PBN1 CEP19 PF14933.6 KFQ95210.1 - 1.2e-35 123.3 2.4 1.3e-35 123.1 2.4 1.0 1 0 0 1 1 1 1 CEP19-like protein LRR_8 PF13855.6 KFQ95211.1 - 1.3e-47 159.3 61.3 1.5e-10 40.7 2.5 9.4 8 2 2 10 10 10 8 Leucine rich repeat LRR_4 PF12799.7 KFQ95211.1 - 6.7e-29 99.5 60.6 0.0017 18.7 0.8 12.1 6 3 9 16 16 16 15 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFQ95211.1 - 6.2e-13 47.4 46.6 3 8.7 0.1 17.3 17 2 0 17 17 17 3 Leucine Rich Repeat LRR_5 PF13306.6 KFQ95211.1 - 0.00015 21.7 0.0 0.19 11.7 0.0 3.9 5 0 0 5 5 5 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFQ95211.1 - 0.00038 20.0 16.2 0.017 14.6 0.2 4.9 1 1 4 5 5 5 3 Leucine-rich repeat LRR_6 PF13516.6 KFQ95211.1 - 0.0026 17.7 56.6 3.1 8.1 0.0 15.3 16 0 0 16 16 16 3 Leucine Rich repeat TauD PF02668.16 KFQ95211.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family WD40 PF00400.32 KFQ95212.1 - 1.9e-15 57.0 0.5 0.00018 22.2 0.0 6.3 5 1 1 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ95212.1 - 2.8e-06 27.5 0.1 0.0071 16.6 0.0 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Prok-RING_4 PF14447.6 KFQ95213.1 - 8.2e-07 28.8 10.2 2.9e-06 27.1 10.2 2.0 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFQ95213.1 - 1.2e-06 28.2 14.7 3.4e-06 26.8 14.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFQ95213.1 - 2.2e-06 27.4 13.2 4.6e-06 26.4 13.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFQ95213.1 - 2.2e-06 27.4 14.3 5.1e-06 26.2 14.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFQ95213.1 - 1.5e-05 24.9 11.1 4.3e-05 23.5 11.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFQ95213.1 - 2.3e-05 24.2 12.5 6e-05 22.9 12.5 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFQ95213.1 - 0.00025 21.1 17.4 0.00036 20.6 15.9 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFQ95213.1 - 0.002 18.4 16.9 0.0052 17.1 16.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 KFQ95213.1 - 2.1 8.2 14.4 6.6 6.6 12.8 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain UBX PF00789.20 KFQ95214.1 - 5.9e-20 71.3 0.0 1.1e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.6 KFQ95214.1 - 2.2e-15 56.6 0.1 4e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 KFQ95214.1 - 3.5e-09 36.3 0.1 1e-07 31.6 0.0 2.6 2 0 0 2 2 2 1 UBA-like domain UIM PF02809.20 KFQ95214.1 - 0.023 14.6 3.6 0.078 12.9 3.6 2.0 1 0 0 1 1 1 0 Ubiquitin interaction motif Thioredox_DsbH PF03190.15 KFQ95214.1 - 0.035 14.1 0.2 0.06 13.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 UBA PF00627.31 KFQ95214.1 - 0.097 12.6 0.1 0.54 10.2 0.3 2.1 2 0 0 2 2 2 0 UBA/TS-N domain Thioredoxin_2 PF13098.6 KFQ95214.1 - 0.12 12.8 0.1 0.27 11.7 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain L6_membrane PF05805.12 KFQ95215.1 - 2.8e-63 212.9 10.6 3.2e-63 212.8 10.6 1.0 1 0 0 1 1 1 1 L6 membrane protein BNR_2 PF13088.6 KFQ95216.1 - 5.2e-33 114.5 0.0 3.4e-29 102.0 0.0 2.1 2 0 0 2 2 2 2 BNR repeat-like domain BNR_3 PF13859.6 KFQ95216.1 - 4.8e-06 26.1 0.0 6e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 KFQ95216.1 - 0.0047 16.7 4.3 4.6 7.6 0.2 3.8 3 0 0 3 3 3 2 BNR/Asp-box repeat Gal-3-0_sulfotr PF06990.11 KFQ95217.1 - 7.1e-133 443.4 8.0 8e-133 443.2 8.0 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 KFQ95217.1 - 0.00023 21.1 0.1 0.00061 19.8 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family ING PF12998.7 KFQ95218.1 - 1.1e-28 99.8 2.4 1.8e-28 99.1 2.4 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KFQ95218.1 - 2.1e-06 27.5 8.1 4.5e-06 26.5 8.1 1.6 1 0 0 1 1 1 1 PHD-finger RRF PF01765.19 KFQ95218.1 - 0.0019 18.2 2.4 0.0027 17.7 2.4 1.2 1 0 0 1 1 1 1 Ribosome recycling factor Spc7 PF08317.11 KFQ95218.1 - 0.0087 15.0 4.1 0.011 14.7 4.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein zf-HC5HC2H PF13771.6 KFQ95218.1 - 0.023 14.9 1.7 0.032 14.5 0.4 1.9 2 0 0 2 2 2 0 PHD-like zinc-binding domain HD_3 PF13023.6 KFQ95218.1 - 0.057 13.3 1.4 0.085 12.8 1.4 1.2 1 0 0 1 1 1 0 HD domain Spectrin_like PF18373.1 KFQ95218.1 - 0.071 13.2 0.2 0.16 12.1 0.2 1.7 1 1 0 1 1 1 0 Spectrin like domain Thymidylate_kin PF02223.17 KFQ95219.1 - 2.6e-46 157.7 0.0 3e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase Peptidase_C54 PF03416.19 KFQ95220.1 - 3.1e-102 341.7 0.0 3.7e-102 341.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 DUF1794 PF08768.11 KFQ95221.1 - 1e-40 139.1 0.0 1.8e-40 138.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) THAP PF05485.12 KFQ95221.1 - 1.2e-12 48.6 0.8 1.2e-12 48.6 0.8 2.1 2 0 0 2 2 2 1 THAP domain DUF4201 PF13870.6 KFQ95221.1 - 0.0036 17.1 0.4 0.0077 16.0 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) HrpB7 PF09486.10 KFQ95221.1 - 0.0047 17.3 1.4 0.0076 16.7 0.2 1.9 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB7) NPC1_N PF16414.5 KFQ95221.1 - 0.029 13.9 0.8 0.053 13.1 0.8 1.3 1 0 0 1 1 1 0 Niemann-Pick C1 N terminus DivIC PF04977.15 KFQ95221.1 - 0.062 13.1 1.5 0.62 9.9 0.3 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF4200 PF13863.6 KFQ95221.1 - 0.12 12.8 2.2 1.1 9.7 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DHR10 PF18595.1 KFQ95221.1 - 0.27 11.3 3.8 0.087 12.9 0.5 1.8 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Csm1_N PF18504.1 KFQ95221.1 - 1.8 9.0 5.5 1.3 9.5 2.2 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain LSDAT_euk PF18139.1 KFQ95222.1 - 1.1e-79 267.6 0.1 2.1e-79 266.7 0.1 1.4 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 KFQ95222.1 - 2.6e-24 85.6 0.1 4.3e-24 84.9 0.1 1.3 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 KFQ95222.1 - 4.6e-20 71.9 17.2 8.3e-20 71.1 17.2 1.4 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KFQ95222.1 - 0.054 12.2 8.7 0.042 12.5 5.0 2.2 1 1 1 2 2 2 0 Polycystin cation channel LDcluster4 PF18306.1 KFQ95222.1 - 0.083 12.5 1.8 6.4 6.4 0.2 2.3 2 0 0 2 2 2 0 SLOG cluster4 family GBP_C PF02841.14 KFQ95222.1 - 9.9 5.5 9.8 5.4 6.3 0.2 2.2 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain LRR_8 PF13855.6 KFQ95223.1 - 2.6e-15 55.9 0.3 1.1e-08 34.7 0.0 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFQ95223.1 - 4.6e-08 33.2 0.9 0.011 16.1 0.0 2.9 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRRNT PF01462.18 KFQ95223.1 - 9.6e-08 31.5 3.1 9.6e-08 31.5 3.1 2.2 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.6 KFQ95223.1 - 3.2e-06 27.1 0.0 4.9e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFQ95223.1 - 2.3e-05 24.3 0.5 0.18 12.5 0.0 4.7 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.6 KFQ95223.1 - 0.0021 17.9 1.4 0.98 9.6 0.0 2.9 2 0 0 2 2 2 2 Leucine Rich repeat EPTP PF03736.17 KFQ95224.1 - 5.7e-93 304.7 28.9 8.8e-21 73.6 1.5 7.7 7 1 0 7 7 7 7 EPTP domain Laminin_G_3 PF13385.6 KFQ95224.1 - 9.5e-05 22.6 0.0 0.00035 20.7 0.0 1.9 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 KFQ95224.1 - 0.001 19.7 0.0 0.0019 18.8 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFQ95224.1 - 0.0029 17.8 0.0 0.0071 16.6 0.0 1.6 1 0 0 1 1 1 1 Laminin G domain DBP10CT PF08147.12 KFQ95224.1 - 0.14 12.4 0.1 0.3 11.4 0.1 1.5 1 0 0 1 1 1 0 DBP10CT (NUC160) domain UQ_con PF00179.26 KFQ95225.1 - 2.7e-47 159.9 0.0 3e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Rad60-SLD PF11976.8 KFQ95226.1 - 1e-25 89.4 0.0 1.1e-25 89.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KFQ95226.1 - 2e-12 46.7 0.1 2.3e-12 46.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family PSI PF01437.25 KFQ95227.1 - 3.8e-06 27.3 7.5 3.8e-06 27.3 7.5 1.7 2 0 0 2 2 1 1 Plexin repeat Shisa PF13908.6 KFQ95227.1 - 0.00011 22.5 1.6 0.00012 22.4 1.6 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 KFQ95227.1 - 0.0031 18.3 0.1 0.005 17.7 0.1 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain PET117 PF15786.5 KFQ95227.1 - 0.0079 16.4 0.2 0.013 15.8 0.2 1.5 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Prominin PF05478.11 KFQ95227.1 - 0.015 13.3 3.8 0.018 13.0 3.8 1.1 1 0 0 1 1 1 0 Prominin Cadherin_C_2 PF16492.5 KFQ95227.1 - 0.018 15.8 0.0 0.026 15.3 0.0 1.3 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal ETRAMP PF09716.10 KFQ95227.1 - 0.019 15.0 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Orthoreo_P10 PF07204.11 KFQ95227.1 - 0.029 14.3 2.1 0.051 13.5 2.1 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 FAM176 PF14851.6 KFQ95227.1 - 0.065 12.9 0.6 0.08 12.6 0.6 1.1 1 0 0 1 1 1 0 FAM176 family TMEM51 PF15345.6 KFQ95227.1 - 0.14 12.0 0.1 0.18 11.7 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 TMEM154 PF15102.6 KFQ95227.1 - 0.16 11.9 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family CCER1 PF15482.6 KFQ95227.1 - 1 9.2 7.6 1.2 9.0 7.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 DAGK_acc PF00609.19 KFQ95228.1 - 9.9e-57 191.7 0.0 1.7e-56 191.0 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAG_kinase_N PF14513.6 KFQ95228.1 - 5.8e-53 179.6 0.4 3.1e-44 151.1 0.1 2.4 1 1 1 2 2 2 2 Diacylglycerol kinase N-terminus DAGK_cat PF00781.24 KFQ95228.1 - 2.8e-27 94.8 0.0 5.4e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 KFQ95228.1 - 2.1e-22 78.7 28.8 3.1e-11 43.0 9.4 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_1 PF00036.32 KFQ95228.1 - 5.8e-12 44.3 1.1 8.6e-05 21.8 0.3 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFQ95228.1 - 7.8e-10 39.1 0.7 2.2e-09 37.7 0.7 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFQ95228.1 - 1.1e-08 34.3 0.1 0.00029 20.5 0.1 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFQ95228.1 - 2e-07 30.2 2.5 0.0036 16.7 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KFQ95228.1 - 2.2e-05 24.2 0.6 0.098 12.5 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFQ95228.1 - 0.0017 18.6 0.1 0.0099 16.2 0.1 2.2 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region C1_2 PF03107.16 KFQ95228.1 - 0.15 12.4 24.5 0.14 12.5 5.8 3.1 3 0 0 3 3 3 0 C1 domain Bcl-2 PF00452.19 KFQ95229.1 - 8.7e-23 80.9 0.1 1.8e-22 79.9 0.1 1.5 2 0 0 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family Pkinase PF00069.25 KFQ95230.1 - 1.6e-68 231.0 0.0 2e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ95230.1 - 1.9e-49 168.3 0.0 3e-49 167.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFQ95230.1 - 1.9e-05 23.6 0.0 3.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF1241 PF06840.11 KFQ95230.1 - 6.9e-05 22.5 0.0 0.00016 21.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Kinase-like PF14531.6 KFQ95230.1 - 0.0064 15.9 0.1 0.021 14.2 0.0 1.8 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFQ95230.1 - 0.047 12.6 0.1 5.5 5.8 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain RhoGEF PF00621.20 KFQ95231.1 - 6.4e-37 127.6 4.2 1.5e-36 126.4 4.2 1.7 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 KFQ95231.1 - 3e-26 92.0 1.0 2.7e-13 50.3 0.2 2.7 2 0 0 2 2 2 2 PH domain FERM_C PF09380.10 KFQ95231.1 - 2.4e-24 85.5 0.1 6e-24 84.3 0.1 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FA PF08736.11 KFQ95231.1 - 1.8e-15 56.8 5.8 1.8e-15 56.7 4.0 2.0 2 0 0 2 2 2 1 FERM adjacent (FA) FERM_N PF09379.10 KFQ95231.1 - 2.1e-14 53.2 0.1 5.7e-14 51.8 0.1 1.8 1 0 0 1 1 1 1 FERM N-terminal domain FERM_M PF00373.18 KFQ95231.1 - 1.3e-13 51.4 0.2 3.9e-13 49.8 0.2 1.8 1 0 0 1 1 1 1 FERM central domain IQ_SEC7_PH PF16453.5 KFQ95231.1 - 4e-07 30.1 0.2 2.9e-06 27.3 0.1 2.4 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 KFQ95231.1 - 0.00025 20.9 4.3 0.55 10.0 0.0 3.4 2 1 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 KFQ95231.1 - 0.0075 16.6 4.0 1.7 9.0 1.3 3.5 3 1 0 3 3 3 1 Pleckstrin homology domain PH_11 PF15413.6 KFQ95231.1 - 0.84 10.1 10.2 2.2 8.8 2.5 4.2 4 1 0 4 4 3 0 Pleckstrin homology domain FRB_dom PF08771.11 KFQ95231.1 - 1.8 9.0 7.8 1.8 9.0 2.4 3.0 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain Septin PF00735.18 KFQ95232.1 - 1.5e-129 431.3 0.1 1.8e-129 431.0 0.1 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFQ95232.1 - 2.6e-08 34.0 0.1 9.6e-08 32.1 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFQ95232.1 - 3.4e-06 26.7 0.2 0.0036 16.9 0.0 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFQ95232.1 - 5.7e-06 26.3 1.5 0.0012 18.8 0.4 2.6 2 1 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 KFQ95232.1 - 0.00013 21.4 0.3 0.00038 19.9 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Ras PF00071.22 KFQ95232.1 - 0.00052 19.6 0.0 0.0011 18.5 0.0 1.7 1 0 0 1 1 1 1 Ras family Dynamin_N PF00350.23 KFQ95232.1 - 0.0009 19.3 1.9 0.075 13.1 0.0 2.9 3 1 1 4 4 4 1 Dynamin family AAA_22 PF13401.6 KFQ95232.1 - 0.0028 17.9 0.2 0.016 15.5 0.2 2.3 1 1 0 1 1 1 1 AAA domain Roc PF08477.13 KFQ95232.1 - 0.0039 17.4 0.0 0.0076 16.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KFQ95232.1 - 0.005 17.3 0.0 0.017 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 KFQ95232.1 - 0.0084 16.6 0.1 0.017 15.7 0.1 1.7 1 1 0 1 1 1 1 ABC transporter Gtr1_RagA PF04670.12 KFQ95232.1 - 0.011 15.1 0.3 0.33 10.3 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 KFQ95232.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KFQ95232.1 - 0.039 13.5 0.0 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region IIGP PF05049.13 KFQ95232.1 - 0.094 11.8 0.4 0.48 9.4 0.0 2.1 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) KH_1 PF00013.29 KFQ95233.1 - 2.7e-194 629.3 60.3 3.6e-16 58.7 0.6 15.7 15 1 0 15 15 15 15 KH domain SLS PF14611.6 KFQ95233.1 - 1.8e-19 70.5 23.2 5e-05 23.2 0.3 9.4 2 2 7 9 9 9 6 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 KFQ95233.1 - 6.2e-17 61.2 47.8 0.013 15.4 1.8 12.5 11 2 1 13 13 13 8 KH domain KH_5 PF13184.6 KFQ95233.1 - 3.7e-08 33.3 28.3 1.6 8.9 0.3 11.2 11 1 1 12 12 12 4 NusA-like KH domain DUF4530 PF15039.6 KFQ95233.1 - 0.0023 18.1 0.1 2.4 8.3 0.0 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4530) SCO1-SenC PF02630.14 KFQ95233.1 - 0.0072 16.2 7.9 9.7 6.1 0.0 8.1 10 0 0 10 10 10 1 SCO1/SenC BMC PF00936.19 KFQ95233.1 - 0.0096 15.9 5.2 55 3.8 0.1 7.4 10 0 0 10 10 10 0 BMC domain Lactamase_B_4 PF13691.6 KFQ95233.1 - 0.015 15.0 0.0 21 4.9 0.0 4.0 3 0 0 3 3 3 0 tRNase Z endonuclease DUF2096 PF09869.9 KFQ95233.1 - 0.032 14.3 18.6 2.6 8.1 0.5 7.4 8 1 0 9 9 9 0 Uncharacterized protein conserved in archaea (DUF2096) KH_4 PF13083.6 KFQ95233.1 - 1.2 9.0 28.0 1.4 8.8 0.0 10.0 9 2 3 12 12 12 0 KH domain DUF531 PF04407.12 KFQ95233.1 - 2.9 8.0 7.2 22 5.1 0.0 5.0 4 2 2 6 6 5 0 Protein of unknown function (DUF531) FtsQ PF03799.15 KFQ95233.1 - 6 7.7 6.2 3.9e+02 1.9 0.0 5.9 5 3 3 8 8 8 0 Cell division protein FtsQ Anoctamin PF04547.12 KFQ95234.1 - 3.3e-159 530.5 22.2 4.1e-159 530.2 22.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KFQ95234.1 - 4.8e-54 183.5 0.2 2.2e-45 155.2 0.0 2.3 2 0 0 2 2 2 2 Dimerisation domain of Ca+-activated chloride-channel, anoctamin LRR_4 PF12799.7 KFQ95235.1 - 4.5e-37 125.5 42.5 1.5e-09 38.0 2.6 7.2 1 1 6 9 9 9 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFQ95235.1 - 2.4e-23 82.5 34.5 1.6e-08 34.3 7.4 4.0 1 1 3 4 4 4 4 Leucine-rich repeat LRR_8 PF13855.6 KFQ95235.1 - 6.6e-23 80.3 39.5 9.8e-08 31.7 8.1 6.3 2 2 3 6 6 6 6 Leucine rich repeat LRR_6 PF13516.6 KFQ95235.1 - 0.00035 20.4 23.7 2.7 8.3 0.0 8.1 8 1 1 9 9 9 3 Leucine Rich repeat Ribosomal_L50 PF10501.9 KFQ95235.1 - 0.014 15.5 3.6 8.4 6.6 0.1 3.6 1 1 2 4 4 4 0 Ribosomal subunit 39S LRR_1 PF00560.33 KFQ95235.1 - 0.085 13.5 32.9 1.7 9.5 0.4 9.1 8 1 0 8 8 8 0 Leucine Rich Repeat UB2H PF14814.6 KFQ95235.1 - 0.11 12.6 8.6 30 4.7 0.0 5.6 2 2 4 7 7 7 0 Bifunctional transglycosylase second domain RNA_pol_Rpb1_5 PF04998.17 KFQ95235.1 - 3.6 6.9 4.8 8 5.8 4.8 1.6 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Pkinase PF00069.25 KFQ95236.1 - 1.2e-56 192.0 0.0 1.8e-56 191.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ95236.1 - 9.2e-25 87.4 0.0 1.6e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PAS_9 PF13426.7 KFQ95236.1 - 3.8e-13 49.6 0.0 7.4e-05 22.9 0.0 4.6 3 1 1 4 4 4 3 PAS domain PAS PF00989.25 KFQ95236.1 - 1.2e-10 41.4 0.0 7.6e-06 25.9 0.0 3.5 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 KFQ95236.1 - 4.9e-05 23.2 0.0 0.054 13.5 0.0 3.6 3 0 0 3 3 3 1 PAS domain Pkinase_fungal PF17667.1 KFQ95236.1 - 0.00054 18.9 0.0 0.033 13.0 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KFQ95236.1 - 0.0087 15.4 0.0 0.042 13.2 0.0 2.0 2 1 0 2 2 2 1 Kinase-like PAS_2 PF08446.11 KFQ95236.1 - 0.028 15.1 0.0 0.11 13.1 0.0 2.1 1 0 0 1 1 1 0 PAS fold Haspin_kinase PF12330.8 KFQ95236.1 - 0.088 11.7 0.1 0.19 10.6 0.1 1.5 1 1 0 1 1 1 0 Haspin like kinase domain EGF PF00008.27 KFQ95237.1 - 4.5e-81 266.6 217.6 4.6e-08 33.2 12.0 14.7 14 0 0 14 14 14 14 EGF-like domain hEGF PF12661.7 KFQ95237.1 - 1.4e-44 149.3 180.6 9.7e-06 26.0 6.4 16.0 14 1 0 14 14 14 13 Human growth factor-like EGF fn3 PF00041.21 KFQ95237.1 - 6.2e-34 116.2 8.0 1.6e-11 44.4 2.0 3.4 3 0 0 3 3 3 3 Fibronectin type III domain NIDO PF06119.14 KFQ95237.1 - 7.7e-27 94.1 0.1 1.7e-26 93.0 0.1 1.6 1 0 0 1 1 1 1 Nidogen-like EGF_2 PF07974.13 KFQ95237.1 - 5.4e-24 84.3 243.1 0.0058 17.0 13.3 14.5 14 0 0 14 14 14 13 EGF-like domain EGF_CA PF07645.15 KFQ95237.1 - 8.7e-23 80.3 199.7 3e-08 33.7 6.0 14.7 8 5 6 14 14 14 11 Calcium-binding EGF domain cEGF PF12662.7 KFQ95237.1 - 0.00041 20.2 0.9 0.00041 20.2 0.9 17.3 17 2 0 17 17 17 7 Complement Clr-like EGF-like DUF2369 PF10179.9 KFQ95237.1 - 0.048 14.0 0.7 7.5 7.0 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2369) Kinesin PF00225.23 KFQ95238.1 - 3.5e-117 391.1 1.3 5.3e-117 390.5 1.3 1.3 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 KFQ95238.1 - 1.5e-92 308.7 0.1 7.9e-92 306.4 0.0 2.3 2 0 0 2 2 2 1 Kinesin-associated DUF3694 PF12473.8 KFQ95238.1 - 1.7e-36 126.2 0.0 4.3e-36 124.9 0.0 1.7 1 0 0 1 1 1 1 Kinesin protein Microtub_bd PF16796.5 KFQ95238.1 - 7.7e-25 87.6 0.3 2.1e-24 86.1 0.3 1.8 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 KFQ95238.1 - 9.3e-14 51.8 0.0 1.2e-12 48.3 0.0 2.9 3 0 0 3 3 3 1 PH domain FHA PF00498.26 KFQ95238.1 - 2e-07 31.2 0.1 9.6e-07 29.1 0.0 2.3 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.8 KFQ95238.1 - 0.015 15.7 0.9 0.015 15.7 0.9 2.7 2 0 0 2 2 2 0 Kinesin protein 1B PH_11 PF15413.6 KFQ95238.1 - 0.12 12.9 0.0 0.36 11.3 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain IstB_IS21 PF01695.17 KFQ95238.1 - 0.18 11.5 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF3584 PF12128.8 KFQ95238.1 - 0.9 7.0 10.2 1.8 6.0 10.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PP2C PF00481.21 KFQ95239.1 - 2.1e-63 214.4 0.2 2.6e-63 214.1 0.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFQ95239.1 - 0.0001 22.0 0.0 0.00019 21.2 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C BTB PF00651.31 KFQ95240.1 - 1.2e-28 99.6 0.0 2e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.25 KFQ95240.1 - 1.6e-22 78.8 26.6 2.8e-08 33.2 0.2 8.8 8 2 0 8 8 8 5 Kelch motif BACK PF07707.15 KFQ95240.1 - 8.6e-22 77.2 0.3 2.4e-21 75.7 0.1 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFQ95240.1 - 6.1e-19 67.6 9.7 7.5e-07 29.2 0.3 7.0 4 2 2 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KFQ95240.1 - 1e-12 47.5 3.9 0.28 11.2 0.0 6.7 7 0 0 7 7 7 5 Kelch motif Kelch_4 PF13418.6 KFQ95240.1 - 4.8e-09 36.1 9.8 0.0032 17.4 0.8 5.3 4 2 1 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KFQ95240.1 - 1.1e-08 35.2 5.0 6.1e-05 23.2 0.9 4.6 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KFQ95240.1 - 4.8e-07 29.6 0.1 0.011 15.8 0.0 3.7 4 0 0 4 4 4 2 Kelch motif 7tm_1 PF00001.21 KFQ95241.1 - 5e-32 111.3 17.8 6.4e-32 110.9 17.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) COX1 PF00115.20 KFQ95241.1 - 0.00021 20.3 2.0 0.00021 20.3 2.0 1.7 2 0 0 2 2 2 1 Cytochrome C and Quinol oxidase polypeptide I DUF4500 PF14937.6 KFQ95241.1 - 0.43 10.6 2.8 1.3 9.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) POT1PC PF16686.5 KFQ95242.1 - 6.3e-41 139.8 0.0 7.1e-39 133.2 0.0 3.2 3 0 0 3 3 3 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KFQ95242.1 - 3.3e-35 121.0 0.1 3.7e-34 117.6 0.0 2.4 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.25 KFQ95242.1 - 3.2e-07 30.2 0.9 6.6 6.8 0.0 5.5 4 1 1 5 5 5 2 OB-fold nucleic acid binding domain REPA_OB_2 PF16900.5 KFQ95242.1 - 0.00051 19.9 0.0 0.0062 16.4 0.0 2.4 2 0 0 2 2 2 1 Replication protein A OB domain SSB PF00436.25 KFQ95242.1 - 0.019 15.0 0.0 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 Single-strand binding protein family RVT_1 PF00078.27 KFQ95244.1 - 0.021 14.4 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) ANF_receptor PF01094.28 KFQ95245.1 - 2.5e-104 349.2 0.0 3.3e-104 348.8 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 KFQ95245.1 - 2.4e-61 207.5 16.0 3.9e-61 206.8 16.0 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 KFQ95245.1 - 1.7e-12 47.1 11.7 3.4e-12 46.1 11.7 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.6 KFQ95245.1 - 5.4e-08 32.9 0.0 4.3e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 Periplasmic binding protein zf-C2H2_assoc2 PF16624.5 KFQ95246.1 - 3.6e-27 95.2 36.2 1.4e-21 77.3 19.5 4.9 5 2 2 7 7 5 2 Unstructured region upstream of a zinc-finger zf-C2H2 PF00096.26 KFQ95246.1 - 2.1e-16 59.4 57.5 0.0023 18.3 1.6 7.7 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ95246.1 - 2.3e-15 56.0 56.1 0.0094 16.7 1.3 7.6 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFQ95246.1 - 4e-14 52.1 11.8 5.1e-14 51.7 5.3 6.6 7 0 0 7 7 7 3 zinc-finger C2H2-type zf-met PF12874.7 KFQ95246.1 - 5.1e-07 29.9 23.0 0.0026 18.1 0.6 6.5 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFQ95246.1 - 8.2e-07 29.3 32.6 0.0092 16.3 1.0 7.1 6 1 1 7 7 7 3 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 KFQ95246.1 - 1.2e-05 25.5 28.0 0.00082 19.6 1.4 5.6 5 0 0 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 KFQ95246.1 - 1.3e-05 24.9 33.8 4.6e-05 23.1 0.6 6.5 6 0 0 6 6 6 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFQ95246.1 - 0.0004 20.6 1.4 0.0004 20.6 1.4 7.6 8 0 0 8 8 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KFQ95246.1 - 0.002 18.4 1.9 0.002 18.4 1.9 4.2 5 0 0 5 5 5 1 C2H2-type zinc ribbon zf-C2H2_9 PF16293.5 KFQ95246.1 - 0.0023 17.8 9.8 7.5 6.5 0.0 4.8 5 0 0 5 5 5 2 C2H2 type zinc-finger (1 copy) zf-H2C2_2 PF13465.6 KFQ95246.1 - 0.016 15.6 0.4 0.016 15.6 0.4 10.1 11 1 0 11 11 9 0 Zinc-finger double domain Vps39_2 PF10367.9 KFQ95246.1 - 0.018 15.5 3.8 0.018 15.5 3.8 4.5 4 1 1 5 5 5 0 Vacuolar sorting protein 39 domain 2 zf-C2H2_6 PF13912.6 KFQ95246.1 - 0.06 13.4 0.6 0.06 13.4 0.6 7.1 7 0 0 7 7 7 0 C2H2-type zinc finger Not1 PF04054.15 KFQ95246.1 - 0.095 11.6 0.2 0.26 10.1 0.2 1.7 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 CpXC PF14353.6 KFQ95246.1 - 0.23 11.5 0.0 0.23 11.5 0.0 3.7 4 2 1 5 5 5 0 CpXC protein zf-C2H2_12 PF18658.1 KFQ95246.1 - 0.4 10.3 15.7 0.16 11.6 0.8 5.0 5 0 0 5 5 5 0 Zinc-finger C2H2-type DUF4535 PF15054.6 KFQ95246.1 - 2.5 7.9 4.5 7 6.5 4.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) DUF2256 PF10013.9 KFQ95246.1 - 3.9 7.7 19.7 11 6.2 0.0 5.5 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) Plexin_cytopl PF08337.12 KFQ95248.1 - 1.2e-221 737.3 11.5 3.5e-221 735.7 11.5 1.9 1 1 0 1 1 1 1 Plexin cytoplasmic RasGAP domain Sema PF01403.19 KFQ95248.1 - 4.9e-65 220.0 4.1 4.9e-65 220.0 4.1 2.3 1 1 1 2 2 2 1 Sema domain TIG PF01833.24 KFQ95248.1 - 4.5e-37 126.0 9.6 3.9e-12 46.1 1.8 5.2 5 0 0 5 5 5 4 IPT/TIG domain TIG_plexin PF17960.1 KFQ95248.1 - 6.2e-15 55.0 2.4 3.5e-14 52.6 0.1 3.3 3 0 0 3 3 3 1 TIG domain PSI PF01437.25 KFQ95248.1 - 6.8e-15 55.3 49.2 1.4e-09 38.4 16.2 3.7 3 0 0 3 3 3 3 Plexin repeat RasGAP PF00616.19 KFQ95248.1 - 0.00025 20.8 0.0 0.005 16.6 0.0 2.9 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase ubiquitin PF00240.23 KFQ95248.1 - 0.021 14.5 0.6 0.9 9.3 0.0 3.6 4 0 0 4 4 4 0 Ubiquitin family ARL2_Bind_BART PF11527.8 KFQ95248.1 - 2.4 8.3 5.6 0.6 10.2 0.2 2.7 3 0 0 3 3 3 0 The ARF-like 2 binding protein BART Pkinase PF00069.25 KFQ95249.1 - 8.6e-61 205.6 0.1 1e-60 205.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ95249.1 - 1.9e-26 92.9 0.1 2.4e-26 92.6 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFQ95249.1 - 6.4e-06 25.7 0.3 9.2e-06 25.1 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFQ95249.1 - 0.0012 18.8 0.0 0.014 15.3 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFQ95249.1 - 0.02 14.2 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 KFQ95250.1 - 1.1e-63 215.1 0.3 1.4e-63 214.7 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ95250.1 - 1.4e-27 96.6 0.1 1.9e-27 96.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFQ95250.1 - 9.3e-05 21.5 1.1 9.9e-05 21.4 0.1 1.4 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KFQ95250.1 - 0.00038 20.5 0.0 0.00086 19.3 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFQ95250.1 - 0.0036 16.7 0.0 0.0072 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFQ95250.1 - 0.0045 16.3 0.0 0.007 15.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like DUF3381 PF11861.8 KFQ95250.1 - 0.019 14.8 1.6 0.077 12.8 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) UvrD_C PF13361.6 KFQ95250.1 - 0.03 13.7 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain FTA2 PF13095.6 KFQ95250.1 - 0.09 12.4 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Fz PF01392.22 KFQ95251.1 - 1.1e-26 93.6 4.6 1.1e-26 93.6 4.6 2.2 2 1 0 2 2 2 1 Fz domain Hist_deacetyl PF00850.19 KFQ95252.1 - 4.5e-82 276.0 0.0 5.5e-82 275.7 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain UPF0061 PF02696.14 KFQ95253.1 - 7.4e-98 328.3 0.1 1.1e-97 327.8 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family XPC-binding PF09280.11 KFQ95253.1 - 0.017 14.8 2.1 0.18 11.6 1.0 2.9 3 0 0 3 3 3 0 XPC-binding domain Metallopep PF12044.8 KFQ95253.1 - 0.022 13.4 0.2 0.03 13.0 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase family SRP19 PF01922.17 KFQ95253.1 - 0.1 13.6 0.2 1.4 9.9 0.1 2.5 2 0 0 2 2 2 0 SRP19 protein TraB PF01963.17 KFQ95254.1 - 4.3e-29 102.2 0.1 8.7e-29 101.2 0.1 1.5 1 1 1 2 2 2 1 TraB family DNA_pol_D_N PF18018.1 KFQ95254.1 - 0.014 15.5 2.2 0.31 11.1 1.2 2.2 2 0 0 2 2 2 0 DNA polymerase delta subunit OB-fold domain Ribosomal_L22e PF01776.17 KFQ95254.1 - 0.023 15.1 0.7 0.059 13.7 0.2 2.0 1 1 0 1 1 1 0 Ribosomal L22e protein family Tetraspanin PF00335.20 KFQ95256.1 - 0.01 15.6 5.1 0.011 15.5 5.1 1.0 1 0 0 1 1 1 0 Tetraspanin family Innexin PF00876.18 KFQ95257.1 - 6.4e-10 38.8 1.6 2.7e-09 36.8 1.4 1.9 1 1 1 2 2 2 1 Innexin DUF2207 PF09972.9 KFQ95257.1 - 0.0049 15.7 0.1 0.0073 15.1 0.1 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Ecl1 PF12855.7 KFQ95257.1 - 0.95 10.6 10.5 1.1 10.4 0.1 2.4 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins AAA_12 PF13087.6 KFQ95258.1 - 1.4e-44 152.1 0.0 2.9e-44 151.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFQ95258.1 - 2.3e-32 112.8 0.0 1.7e-15 57.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain S1-like PF14444.6 KFQ95258.1 - 1.2e-13 50.8 0.3 1.6e-05 24.7 0.6 4.2 4 0 0 4 4 4 3 S1-like AAA_30 PF13604.6 KFQ95258.1 - 6.1e-13 48.9 0.0 1.3e-12 47.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFQ95258.1 - 9.9e-08 32.4 0.0 3.3e-07 30.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KFQ95258.1 - 0.00019 21.5 0.0 0.00049 20.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFQ95258.1 - 0.0011 18.8 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD_C_2 PF13538.6 KFQ95258.1 - 0.017 14.9 0.5 0.12 12.2 0.3 2.5 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain PhoH PF02562.16 KFQ95258.1 - 0.046 13.2 0.0 4.5 6.7 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA PF00004.29 KFQ95258.1 - 0.051 14.0 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 KFQ95258.1 - 0.065 12.7 0.0 2.7 7.5 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KFQ95258.1 - 0.069 13.4 0.0 0.27 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain KASH PF10541.9 KFQ95259.1 - 0.49 10.7 6.1 2.5 8.4 0.1 2.7 2 0 0 2 2 2 0 Nuclear envelope localisation domain IL17_R_N PF15037.6 KFQ95260.1 - 8.2e-36 123.8 11.6 4.3e-35 121.4 11.6 1.8 1 1 0 1 1 1 1 Interleukin-17 receptor extracellular region RVT_1 PF00078.27 KFQ95261.1 - 0.011 15.3 0.0 0.033 13.7 0.0 1.6 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 KFQ95264.1 - 1.2e-50 172.3 0.0 1.8e-50 171.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ95264.1 - 8.7e-16 58.0 0.0 1.3e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ95264.1 - 9.6e-08 31.7 0.0 1.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFQ95264.1 - 0.00016 21.1 0.0 0.00027 20.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFQ95264.1 - 0.0062 16.2 0.0 0.0089 15.6 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KFQ95264.1 - 0.075 12.9 0.2 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-ZPR1 PF03367.13 KFQ95264.1 - 0.19 11.6 0.1 13 5.6 0.0 2.1 2 0 0 2 2 2 0 ZPR1 zinc-finger domain EGF_CA PF07645.15 KFQ95265.1 - 1.7e-14 53.7 30.9 3.7e-11 43.0 11.1 7.2 4 2 2 6 6 6 2 Calcium-binding EGF domain DUF3456 PF11938.8 KFQ95265.1 - 4.4e-06 27.3 6.7 0.00026 21.5 1.7 3.3 3 1 1 4 4 4 2 TLR4 regulator and MIR-interacting MSAP VSP PF03302.13 KFQ95265.1 - 0.00068 18.6 61.3 0.041 12.8 28.8 2.7 1 1 1 2 2 2 2 Giardia variant-specific surface protein Plasmod_Pvs28 PF06247.11 KFQ95265.1 - 0.0016 18.7 10.8 0.0016 18.7 10.8 5.5 3 2 0 3 3 3 1 Pvs28 EGF domain EGF PF00008.27 KFQ95265.1 - 0.0017 18.6 0.8 0.0017 18.6 0.8 6.6 8 1 1 9 9 9 3 EGF-like domain hEGF PF12661.7 KFQ95265.1 - 0.0022 18.6 0.9 0.0022 18.6 0.9 7.7 8 1 0 8 8 8 1 Human growth factor-like EGF cEGF PF12662.7 KFQ95265.1 - 0.0027 17.6 10.7 0.012 15.5 2.0 6.7 5 1 0 5 5 5 2 Complement Clr-like EGF-like EGF_3 PF12947.7 KFQ95265.1 - 0.031 14.5 5.3 0.031 14.5 5.3 5.9 5 2 1 6 6 6 0 EGF domain Glyco_transf_22 PF03901.17 KFQ95267.1 - 4.5e-44 151.3 30.7 5.6e-44 151.0 30.7 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family zf-BED PF02892.15 KFQ95268.1 - 1.2e-63 210.8 29.5 1.8e-16 59.9 0.4 4.6 4 0 0 4 4 4 4 BED zinc finger Dimer_Tnp_hAT PF05699.14 KFQ95268.1 - 2.6e-11 43.1 0.6 2.6e-11 43.1 0.6 2.6 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region PyrI_C PF02748.15 KFQ95268.1 - 6.7e-05 22.7 5.0 2.5 8.1 0.1 4.5 4 0 0 4 4 4 3 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_12 PF18658.1 KFQ95268.1 - 0.14 11.8 11.7 1 9.0 0.1 4.3 4 0 0 4 4 4 0 Zinc-finger C2H2-type Inhibitor_Mig-6 PF11555.8 KFQ95268.1 - 0.74 10.0 2.5 3.9 7.6 2.5 2.3 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 zinc_ribbon_9 PF14369.6 KFQ95268.1 - 5.5 7.3 9.1 41 4.6 0.0 3.9 4 0 0 4 4 4 0 zinc-ribbon zf-HC5HC2H_2 PF13832.6 KFQ95269.1 - 4.3e-37 126.6 4.5 4.3e-37 126.6 4.5 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 KFQ95269.1 - 4.1e-34 118.2 2.1 4.1e-34 118.2 2.1 2.5 3 1 0 3 3 3 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 KFQ95269.1 - 3.4e-26 91.3 2.9 3.4e-26 91.3 2.9 3.5 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.25 KFQ95269.1 - 2.1e-25 88.6 0.4 5.4e-25 87.3 0.4 1.7 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.17 KFQ95269.1 - 4.3e-18 65.5 0.0 2.3e-17 63.2 0.0 2.3 1 0 0 1 1 1 1 PWWP domain PHD_2 PF13831.6 KFQ95269.1 - 1.9e-13 49.7 4.4 1.9e-13 49.7 4.4 3.0 2 1 0 2 2 2 1 PHD-finger PHD PF00628.29 KFQ95269.1 - 6.5e-07 29.1 27.9 2.7e-06 27.2 13.4 2.9 2 0 0 2 2 2 2 PHD-finger AAA_23 PF13476.6 KFQ95269.1 - 0.044 14.3 9.2 0.04 14.4 1.3 2.9 3 0 0 3 3 3 0 AAA domain DUF3439 PF11921.8 KFQ95269.1 - 0.073 13.0 1.4 0.25 11.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DNA_topoisoIV PF00521.20 KFQ95269.1 - 0.11 11.4 4.1 0.2 10.5 4.1 1.4 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A RVT_1 PF00078.27 KFQ95270.1 - 0.061 12.8 0.0 0.087 12.3 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) TAFA PF12020.8 KFQ95271.1 - 1.4e-44 150.5 9.9 1.6e-44 150.3 9.9 1.0 1 0 0 1 1 1 1 TAFA family RabGAP-TBC PF00566.18 KFQ95274.1 - 1.4e-50 171.9 1.3 1.4e-50 171.9 1.3 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain ELMO_CED12 PF04727.13 KFQ95274.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.8 1 1 0 1 1 1 0 ELMO/CED-12 family DAGK_cat PF00781.24 KFQ95275.1 - 6e-22 77.6 0.0 9.9e-22 76.9 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain GRAM PF02893.20 KFQ95276.1 - 1.7e-22 79.4 0.0 3.7e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 GRAM domain PRT_C PF08372.10 KFQ95276.1 - 0.00051 19.8 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Plant phosphoribosyltransferase C-terminal Tmemb_cc2 PF10267.9 KFQ95276.1 - 0.024 13.8 3.1 0.04 13.1 3.1 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF639 PF04842.12 KFQ95276.1 - 0.14 11.6 1.5 0.15 11.4 0.2 1.6 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) Histone PF00125.24 KFQ95277.1 - 5.6e-26 91.4 0.4 7.2e-26 91.1 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFQ95277.1 - 9.1e-07 29.1 0.7 1.8e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KFQ95277.1 - 0.0034 17.8 0.0 0.006 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KFQ95277.1 - 0.0047 17.0 0.3 0.0055 16.7 0.3 1.2 1 0 0 1 1 1 1 YscO-like protein Cadherin PF00028.17 KFQ95278.1 - 4.1e-168 546.4 14.7 5.8e-23 81.2 0.8 9.7 9 0 0 9 9 9 9 Cadherin domain GAIN PF16489.5 KFQ95278.1 - 2.9e-68 229.4 0.3 4.7e-68 228.8 0.3 1.4 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Laminin_G_2 PF02210.24 KFQ95278.1 - 6.4e-38 130.2 0.1 3.5e-24 85.8 0.0 3.3 2 0 0 2 2 2 2 Laminin G domain 7tm_2 PF00002.24 KFQ95278.1 - 2.8e-35 121.8 15.3 2.8e-34 118.5 15.3 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Laminin_G_1 PF00054.23 KFQ95278.1 - 4.9e-21 75.3 0.1 5.4e-15 55.8 0.0 3.8 2 1 0 2 2 2 2 Laminin G domain EGF PF00008.27 KFQ95278.1 - 1.6e-19 69.8 112.0 4.9e-07 29.9 8.2 9.0 9 0 0 9 9 7 6 EGF-like domain Cadherin_3 PF16184.5 KFQ95278.1 - 4.2e-18 65.4 13.6 0.0051 16.8 0.1 8.5 8 0 0 8 8 8 5 Cadherin-like GPS PF01825.21 KFQ95278.1 - 7.6e-15 55.2 3.4 7.6e-15 55.2 3.4 3.2 2 1 0 2 2 1 1 GPCR proteolysis site, GPS, motif Laminin_EGF PF00053.24 KFQ95278.1 - 2.8e-08 33.8 12.9 2.8e-08 33.8 12.9 8.8 6 2 3 9 9 7 2 Laminin EGF domain Cadherin_2 PF08266.12 KFQ95278.1 - 1.5e-07 31.1 0.0 1.5 8.7 0.0 7.1 7 0 0 7 7 7 1 Cadherin-like hEGF PF12661.7 KFQ95278.1 - 2.5e-07 31.1 84.9 0.00021 21.8 6.5 8.7 8 0 0 8 8 7 4 Human growth factor-like EGF Cadherin_4 PF17803.1 KFQ95278.1 - 5.5e-07 30.1 45.2 0.13 12.9 0.0 9.6 9 0 0 9 9 9 4 Bacterial cadherin-like domain Dicty_CAR PF05462.11 KFQ95278.1 - 0.00073 18.8 7.3 0.0014 17.8 7.3 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor PepSY PF03413.19 KFQ95278.1 - 0.077 13.6 1.2 6.1 7.5 0.0 3.5 4 0 0 4 4 4 0 Peptidase propeptide and YPEB domain tRNA_Me_trans PF03054.16 KFQ95279.1 - 7.4e-123 409.8 0.0 2e-122 408.4 0.0 1.6 1 1 0 1 1 1 1 tRNA methyl transferase GTSE1_N PF15259.6 KFQ95280.1 - 1.1e-58 197.5 3.6 1.1e-58 197.5 3.6 2.3 2 0 0 2 2 2 1 G-2 and S-phase expressed 1 Gemini_C4 PF01492.17 KFQ95280.1 - 0.029 14.3 0.1 0.15 12.0 0.0 2.3 2 0 0 2 2 2 0 Geminivirus C4 protein ATP19 PF11022.8 KFQ95280.1 - 1.3 9.5 6.5 0.95 9.9 1.5 3.2 2 0 0 2 2 2 0 ATP synthase subunit K CGI-121 PF08617.10 KFQ95281.1 - 5.6e-45 153.4 0.4 6.3e-45 153.2 0.4 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 SAPIS-gp6 PF16722.5 KFQ95281.1 - 0.13 12.7 0.4 0.35 11.3 0.4 1.7 1 1 1 2 2 2 0 Pathogenicity island protein gp6 in Staphylococcus Exonuc_VII_S PF02609.16 KFQ95281.1 - 0.16 12.1 0.1 0.43 10.7 0.1 1.7 1 0 0 1 1 1 0 Exonuclease VII small subunit DIE2_ALG10 PF04922.12 KFQ95282.1 - 4.7e-135 450.9 28.0 6e-135 450.5 28.0 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Glyco_hydro_31 PF01055.26 KFQ95283.1 - 9.3e-64 216.2 0.4 1e-63 216.1 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Aminotran_MocR PF12897.7 KFQ95283.1 - 0.12 11.1 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Kinesin PF00225.23 KFQ95284.1 - 3e-107 358.4 0.4 3e-107 358.4 0.4 3.2 3 1 0 4 4 4 1 Kinesin motor domain WD40 PF00400.32 KFQ95284.1 - 2.3e-30 104.2 7.7 3.6e-05 24.4 0.1 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Microtub_bd PF16796.5 KFQ95284.1 - 4.1e-23 82.0 0.0 4.1e-23 82.0 0.0 2.9 2 1 0 2 2 2 1 Microtubule binding Csm1_N PF18504.1 KFQ95284.1 - 0.017 15.4 0.9 0.017 15.4 0.9 9.9 7 3 3 11 11 11 0 Csm1 N-terminal domain ABC_membrane_2 PF06472.15 KFQ95285.1 - 9.3e-101 336.7 4.8 1.3e-100 336.3 4.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KFQ95285.1 - 2.4e-18 67.0 0.0 4.7e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFQ95285.1 - 8.9e-05 22.4 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFQ95285.1 - 0.00087 19.8 0.2 0.0044 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFQ95285.1 - 0.0042 16.8 0.0 0.0098 15.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.15 KFQ95285.1 - 0.0083 16.1 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain Cyto_heme_lyase PF01265.17 KFQ95285.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase Adeno_IVa2 PF02456.15 KFQ95285.1 - 0.022 13.6 0.1 0.039 12.7 0.1 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein SMC_N PF02463.19 KFQ95285.1 - 0.023 14.2 0.1 0.18 11.2 0.1 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain SseC PF04888.12 KFQ95285.1 - 0.029 14.0 0.0 0.068 12.8 0.0 1.5 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family ARID PF01388.21 KFQ95285.1 - 0.066 13.9 0.1 0.22 12.2 0.1 1.9 1 0 0 1 1 1 0 ARID/BRIGHT DNA binding domain AAA_16 PF13191.6 KFQ95285.1 - 0.12 12.8 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Sugar_tr PF00083.24 KFQ95286.1 - 1.5e-93 314.2 11.9 8.3e-69 232.6 2.0 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFQ95286.1 - 2.6e-15 56.2 23.4 2.2e-07 30.1 2.2 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Ral PF11058.8 KFQ95286.1 - 0.077 12.6 1.1 0.15 11.6 1.1 1.4 1 0 0 1 1 1 0 Antirestriction protein Ral PSI_integrin PF17205.3 KFQ95286.1 - 1.7 8.5 5.9 3.3 7.5 5.9 1.5 1 0 0 1 1 1 0 Integrin plexin domain COPIIcoated_ERV PF07970.12 KFQ95287.1 - 6.6e-50 170.0 0.3 9.6e-50 169.5 0.3 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KFQ95287.1 - 1e-24 86.7 0.3 2.3e-24 85.6 0.3 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Laminin_EGF PF00053.24 KFQ95288.1 - 2e-108 354.4 246.7 3.3e-12 46.3 14.4 13.6 13 0 0 13 13 13 13 Laminin EGF domain Laminin_N PF00055.17 KFQ95288.1 - 1.4e-51 175.4 0.0 1.4e-51 175.4 0.0 2.5 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) Desmo_N PF06771.11 KFQ95288.1 - 1.6 9.2 6.0 24 5.3 0.0 3.7 3 0 0 3 3 3 0 Viral Desmoplakin N-terminus Pyr_redox_2 PF07992.14 KFQ95289.1 - 1.9e-66 224.3 7.6 1.9e-66 224.3 7.6 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFQ95289.1 - 3.2e-41 140.0 1.0 9.2e-41 138.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFQ95289.1 - 3.4e-18 66.0 7.0 9.4e-17 61.4 1.3 3.0 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFQ95289.1 - 2.5e-10 40.1 3.4 2.5e-07 30.3 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFQ95289.1 - 4.5e-09 36.2 0.2 4.5e-09 36.2 0.2 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFQ95289.1 - 9.2e-09 34.9 3.8 9.5e-07 28.2 0.3 3.0 3 0 0 3 3 3 2 FAD binding domain GIDA PF01134.22 KFQ95289.1 - 2.2e-06 27.0 10.1 4.9e-06 25.9 4.3 2.9 2 1 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KFQ95289.1 - 8.6e-06 25.9 7.3 6.5e-05 23.1 0.1 2.7 3 0 0 3 3 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KFQ95289.1 - 8.6e-05 21.9 4.7 0.0068 15.7 0.2 3.4 4 0 0 4 4 4 1 FAD binding domain K_oxygenase PF13434.6 KFQ95289.1 - 8.6e-05 21.8 1.9 0.12 11.4 0.2 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KFQ95289.1 - 0.00015 20.6 11.2 0.0017 17.2 0.5 3.7 4 0 0 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.21 KFQ95289.1 - 0.0002 20.7 8.9 0.034 13.5 0.9 3.1 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KFQ95289.1 - 0.00061 19.1 0.9 0.0013 18.0 0.1 2.0 2 0 0 2 2 2 1 Thi4 family UDPG_MGDP_dh_N PF03721.14 KFQ95289.1 - 0.0045 16.6 7.6 1.3 8.6 0.2 3.6 4 0 0 4 4 4 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 KFQ95289.1 - 0.045 13.3 10.3 3.2 7.2 0.1 4.0 4 0 0 4 4 4 0 FAD dependent oxidoreductase UPF0227 PF05728.12 KFQ95289.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) 3HCDH_N PF02737.18 KFQ95289.1 - 0.14 12.0 5.5 1.3 8.9 1.2 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KFQ95289.1 - 0.42 9.9 2.8 2.8 7.3 0.2 2.9 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zf_Hakai PF18408.1 KFQ95290.1 - 2.5e-21 75.0 2.3 5e-21 74.1 2.3 1.5 1 0 0 1 1 1 1 C2H2 Hakai zinc finger domain zf-C3HC4_3 PF13920.6 KFQ95290.1 - 2.5e-05 24.0 7.9 5.2e-05 23.0 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFQ95290.1 - 0.0012 18.7 7.5 0.0027 17.6 7.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFQ95290.1 - 0.0013 18.6 8.7 0.0027 17.6 8.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFQ95290.1 - 0.0016 18.3 9.6 0.0066 16.3 9.6 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFQ95290.1 - 0.02 14.8 6.5 0.043 13.7 6.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DZR PF12773.7 KFQ95290.1 - 0.043 13.8 7.2 0.21 11.6 7.0 2.1 1 1 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 KFQ95290.1 - 0.053 13.5 10.4 0.1 12.6 10.4 1.4 1 0 0 1 1 1 0 zinc-ribbons zf-RING_2 PF13639.6 KFQ95290.1 - 0.069 13.5 8.5 0.17 12.3 8.5 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 KFQ95290.1 - 0.11 12.5 6.8 0.37 10.8 6.8 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 KFQ95290.1 - 0.77 9.6 8.1 0.1 12.4 3.7 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.20 KFQ95290.1 - 0.8 9.5 5.6 1.9 8.3 5.6 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger C1_4 PF07975.12 KFQ95290.1 - 5.8 7.2 10.0 7.3 6.9 8.5 2.0 2 1 0 2 2 2 0 TFIIH C1-like domain Sulfate_transp PF00916.20 KFQ95291.1 - 3.8e-106 355.1 23.1 4.9e-106 354.7 23.1 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFQ95291.1 - 7.8e-34 115.8 0.6 1.5e-33 114.9 0.6 1.5 1 0 0 1 1 1 1 STAS domain 7tm_6 PF02949.20 KFQ95291.1 - 0.18 10.8 1.6 6.5 5.7 0.1 2.4 2 0 0 2 2 2 0 7tm Odorant receptor Bap31 PF05529.12 KFQ95292.1 - 1.8e-31 108.8 3.0 1.8e-31 108.8 3.0 1.9 2 1 1 3 3 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KFQ95292.1 - 1.1e-12 47.7 7.6 1.1e-12 47.7 7.6 2.4 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain ADIP PF11559.8 KFQ95292.1 - 0.00073 19.6 15.2 0.0013 18.8 15.0 1.5 1 1 0 1 1 1 1 Afadin- and alpha -actinin-Binding MPS2 PF17060.5 KFQ95292.1 - 0.00093 18.6 7.5 0.00093 18.6 7.5 1.5 2 0 0 2 2 2 1 Monopolar spindle protein 2 Sec34 PF04136.15 KFQ95292.1 - 0.0029 17.5 9.7 0.017 15.0 3.1 2.6 3 0 0 3 3 3 1 Sec34-like family APG6_N PF17675.1 KFQ95292.1 - 0.0048 17.4 17.3 0.0077 16.8 17.3 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region MAD PF05557.13 KFQ95292.1 - 0.0058 15.1 15.5 0.0071 14.8 15.5 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Cluap1 PF10234.9 KFQ95292.1 - 0.0064 15.9 10.4 0.0083 15.6 10.4 1.3 1 0 0 1 1 1 1 Clusterin-associated protein-1 MscS_porin PF12795.7 KFQ95292.1 - 0.0075 15.8 14.6 0.01 15.4 14.6 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain DUF1664 PF07889.12 KFQ95292.1 - 0.0081 16.2 5.9 0.013 15.5 4.5 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) YabA PF06156.13 KFQ95292.1 - 0.0099 16.5 11.7 0.38 11.4 4.1 2.4 1 1 1 2 2 2 2 Initiation control protein YabA PspA_IM30 PF04012.12 KFQ95292.1 - 0.014 15.0 18.6 0.02 14.4 18.6 1.2 1 0 0 1 1 1 0 PspA/IM30 family Cep57_MT_bd PF06657.13 KFQ95292.1 - 0.015 15.7 6.5 0.015 15.7 6.5 2.4 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 AAA_11 PF13086.6 KFQ95292.1 - 0.026 14.3 3.0 0.031 14.1 3.0 1.2 1 0 0 1 1 1 0 AAA domain AATF-Che1 PF13339.6 KFQ95292.1 - 0.041 14.5 8.0 0.08 13.6 8.0 1.5 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF3450 PF11932.8 KFQ95292.1 - 0.045 13.0 11.8 0.069 12.4 11.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) RACo_linker PF17650.1 KFQ95292.1 - 0.05 13.5 0.1 0.16 11.9 0.1 1.8 1 1 0 1 1 1 0 RACo linker region End3 PF12761.7 KFQ95292.1 - 0.067 13.4 12.1 0.087 13.0 12.1 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Fez1 PF06818.15 KFQ95292.1 - 0.077 13.4 14.3 0.11 12.9 14.3 1.2 1 0 0 1 1 1 0 Fez1 DUF4878 PF12870.7 KFQ95292.1 - 0.13 12.5 7.4 0.24 11.7 7.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) Fzo_mitofusin PF04799.13 KFQ95292.1 - 0.15 11.6 7.5 0.17 11.4 5.9 1.8 1 1 1 2 2 2 0 fzo-like conserved region KASH_CCD PF14662.6 KFQ95292.1 - 0.17 11.7 15.9 0.41 10.4 15.9 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH CENP-H PF05837.12 KFQ95292.1 - 0.18 12.2 16.8 0.28 11.6 10.5 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) HIP1_clath_bdg PF16515.5 KFQ95292.1 - 0.2 12.3 13.5 0.38 11.4 13.5 1.6 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Sec2p PF06428.11 KFQ95292.1 - 0.2 11.6 14.0 0.16 12.0 8.0 2.4 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Ycf54 PF10674.9 KFQ95292.1 - 0.22 11.8 3.0 0.33 11.3 2.1 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF2488) Syntaxin PF00804.25 KFQ95292.1 - 0.22 11.1 10.8 0.36 10.5 10.8 1.3 1 0 0 1 1 1 0 Syntaxin Atg14 PF10186.9 KFQ95292.1 - 0.25 10.4 8.9 0.26 10.3 8.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Mod_r PF07200.13 KFQ95292.1 - 0.32 11.1 14.9 1.6 8.8 14.9 2.0 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Cnn_1N PF07989.11 KFQ95292.1 - 0.39 10.9 12.4 0.24 11.6 8.9 2.4 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 JIP_LZII PF16471.5 KFQ95292.1 - 0.43 10.8 9.8 4.1 7.6 1.3 3.2 2 1 0 3 3 3 0 JNK-interacting protein leucine zipper II CC2-LZ PF16516.5 KFQ95292.1 - 0.52 10.7 16.5 1.1 9.7 7.1 3.2 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator FapA PF03961.13 KFQ95292.1 - 0.7 8.4 9.0 0.9 8.1 9.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A APC_N_CC PF16689.5 KFQ95292.1 - 0.84 9.7 8.2 1.2 9.2 1.7 2.8 1 1 2 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain DivIVA PF05103.13 KFQ95292.1 - 0.91 9.6 13.7 1.8 8.7 13.7 1.5 1 0 0 1 1 1 0 DivIVA protein Spc7 PF08317.11 KFQ95292.1 - 0.93 8.3 16.1 1.3 7.9 16.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 KFQ95292.1 - 1 9.5 15.4 2.4 8.2 13.7 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HALZ PF02183.18 KFQ95292.1 - 1.3 9.3 11.3 3.1 8.1 0.2 3.4 3 1 0 3 3 3 0 Homeobox associated leucine zipper Syntaxin_2 PF14523.6 KFQ95292.1 - 1.3 9.4 9.3 2.3 8.7 7.6 2.0 1 1 1 2 2 2 0 Syntaxin-like protein Exonuc_VII_L PF02601.15 KFQ95292.1 - 1.4 8.4 7.8 1.5 8.3 7.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit LPP PF04728.13 KFQ95292.1 - 1.4 9.3 8.9 0.21 12.0 1.3 2.6 1 1 0 2 2 2 0 Lipoprotein leucine-zipper Tho2 PF11262.8 KFQ95292.1 - 1.5 7.9 9.8 2.5 7.2 9.8 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF1192 PF06698.11 KFQ95292.1 - 1.6 8.9 7.0 3.2 7.9 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Uds1 PF15456.6 KFQ95292.1 - 1.6 8.9 15.5 1.8 8.7 13.4 2.0 1 1 1 2 2 2 0 Up-regulated During Septation Fib_alpha PF08702.10 KFQ95292.1 - 1.8 8.7 8.5 4.5 7.4 8.0 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Uso1_p115_C PF04871.13 KFQ95292.1 - 2.1 8.7 21.9 1.1 9.7 11.5 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region OmpH PF03938.14 KFQ95292.1 - 2.5 8.4 19.1 0.56 10.6 9.8 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Occludin_ELL PF07303.13 KFQ95292.1 - 2.6 8.8 10.8 3 8.6 4.6 2.3 1 1 1 2 2 2 0 Occludin homology domain bZIP_Maf PF03131.17 KFQ95292.1 - 2.8 8.5 13.0 1 9.9 1.6 2.9 1 1 2 3 3 3 0 bZIP Maf transcription factor THOC7 PF05615.13 KFQ95292.1 - 2.9 8.2 15.1 64 3.8 15.0 2.2 1 1 0 1 1 1 0 Tho complex subunit 7 UPF0449 PF15136.6 KFQ95292.1 - 3.3 8.2 12.2 2.2 8.8 2.9 2.8 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 ZapB PF06005.12 KFQ95292.1 - 3.4 8.2 18.4 2.3e+03 -0.9 18.4 2.9 1 1 0 1 1 1 0 Cell division protein ZapB FlaC_arch PF05377.11 KFQ95292.1 - 4.8 7.7 6.5 2.8 8.4 2.0 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF4140 PF13600.6 KFQ95292.1 - 5 7.6 10.6 49 4.5 10.9 2.1 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Cep57_CLD_2 PF14197.6 KFQ95292.1 - 5.3 7.2 14.9 3.7 7.7 1.5 3.2 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 bZIP_1 PF00170.21 KFQ95292.1 - 5.4 7.2 14.3 2.1 8.5 1.0 3.3 1 1 1 2 2 1 0 bZIP transcription factor DUF2203 PF09969.9 KFQ95292.1 - 6.2 7.6 9.5 12 6.7 8.2 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) PIEZO PF15917.5 KFQ95292.1 - 6.2 6.2 11.9 4.6 6.6 10.1 1.6 1 1 1 2 2 2 0 Piezo Nup54_57_C PF18570.1 KFQ95292.1 - 7.4 6.3 9.1 5.2 6.7 2.7 2.7 2 1 1 3 3 3 0 NUP57/Nup54 C-terminal domain SlyX PF04102.12 KFQ95292.1 - 8.6 7.1 8.3 2.4 8.9 2.2 2.5 1 1 0 2 2 2 0 SlyX Seryl_tRNA_N PF02403.22 KFQ95292.1 - 9 6.6 15.2 17 5.7 14.5 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF948 PF06103.11 KFQ95292.1 - 9.3 6.6 10.7 5.2 7.4 1.5 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.6 KFQ95292.1 - 9.5 5.5 14.0 8.5 5.6 13.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Dus PF01207.17 KFQ95293.1 - 1.5e-74 250.9 0.2 1.8e-74 250.6 0.2 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KFQ95293.1 - 1.9e-06 27.5 0.6 0.0024 17.4 0.1 1.5 1 1 1 2 2 2 2 Histidine biosynthesis protein TMP-TENI PF02581.17 KFQ95293.1 - 0.0063 15.9 0.1 0.012 14.9 0.1 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase Oxidored_FMN PF00724.20 KFQ95293.1 - 0.026 13.8 0.0 0.048 12.9 0.0 1.5 1 1 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family ThiG PF05690.14 KFQ95293.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG COG5 PF10392.9 KFQ95294.1 - 3.3e-31 108.2 2.2 3.3e-31 108.2 2.2 2.9 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.11 KFQ95294.1 - 8.5e-10 38.6 3.1 2.7e-09 37.0 0.3 3.4 2 1 1 3 3 3 1 Vps51/Vps67 COG2 PF06148.11 KFQ95294.1 - 0.0003 20.9 0.5 0.0003 20.9 0.5 4.0 4 1 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 FapA PF03961.13 KFQ95294.1 - 0.036 12.7 0.4 0.097 11.3 0.0 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A DLP_helical PF18709.1 KFQ95294.1 - 0.38 9.9 3.8 0.25 10.5 0.1 2.4 3 0 0 3 3 3 0 Dynamin-like helical domain Vps54_N PF10475.9 KFQ95294.1 - 0.46 9.7 6.0 0.099 11.9 1.0 2.1 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Fib_alpha PF08702.10 KFQ95294.1 - 0.62 10.3 4.6 3.4 7.9 0.3 3.6 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Fzo_mitofusin PF04799.13 KFQ95294.1 - 8.2 6.0 6.9 4.4 6.8 0.1 3.3 3 1 0 3 3 3 0 fzo-like conserved region 7tm_1 PF00001.21 KFQ95295.1 - 2e-25 89.6 22.5 2.6e-25 89.3 22.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pex24p PF06398.11 KFQ95295.1 - 0.62 9.0 15.8 0.17 10.8 12.0 2.1 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin DUF1980 PF09323.10 KFQ95295.1 - 3.3 7.6 12.4 2.3 8.1 0.9 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1980) AXH PF08517.12 KFQ95297.1 - 5.9e-35 120.3 0.0 1.1e-34 119.4 0.0 1.5 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) HMG_box PF00505.19 KFQ95297.1 - 6.6e-15 55.3 0.9 1.2e-14 54.4 0.9 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFQ95297.1 - 2.7e-09 37.5 1.6 5.2e-09 36.6 1.6 1.5 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 KFQ95297.1 - 0.0032 16.8 0.1 0.0055 16.0 0.1 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box cNMP_binding PF00027.29 KFQ95298.1 - 2.7e-37 126.7 0.1 6.8e-20 70.9 0.1 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PI3Ka PF00613.20 KFQ95300.1 - 2.5e-63 212.9 1.5 2.5e-63 212.9 1.5 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KFQ95300.1 - 4.9e-57 193.6 0.7 2.2e-56 191.4 0.7 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_rbd PF00794.18 KFQ95300.1 - 6.1e-27 93.9 6.4 7.6e-26 90.4 0.0 3.6 4 0 0 4 4 4 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 KFQ95300.1 - 8.7e-16 58.1 0.3 2.8e-15 56.5 0.1 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 KFQ95300.1 - 0.0037 16.6 0.0 0.0067 15.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) BMFP PF04380.13 KFQ95300.1 - 0.14 12.7 0.3 0.88 10.1 0.1 2.4 2 0 0 2 2 2 0 Membrane fusogenic activity NAPRTase PF04095.16 KFQ95301.1 - 9.8e-73 244.7 0.0 1.3e-72 244.3 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF5598 PF18127.1 KFQ95301.1 - 3.5e-36 123.6 2.3 3.5e-36 123.6 2.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5598) MARVEL PF01284.23 KFQ95302.1 - 4.6e-35 120.8 14.0 6.1e-35 120.4 14.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF996 PF06195.13 KFQ95302.1 - 0.52 10.6 6.1 0.2 11.9 3.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF996) SieB PF14163.6 KFQ95302.1 - 0.85 9.1 3.1 0.81 9.2 1.7 1.6 1 1 0 1 1 1 0 Super-infection exclusion protein B Cadherin PF00028.17 KFQ95303.1 - 7.3e-56 186.6 4.8 2.3e-15 56.8 0.1 6.3 6 0 0 6 6 6 6 Cadherin domain Cadherin_3 PF16184.5 KFQ95303.1 - 3e-12 46.5 0.1 0.0038 17.2 0.1 4.8 4 0 0 4 4 4 3 Cadherin-like Cadherin_2 PF08266.12 KFQ95303.1 - 2.6e-06 27.2 0.0 4.7e-05 23.1 0.0 3.1 4 1 0 4 4 4 1 Cadherin-like Invasin_D3 PF09134.10 KFQ95303.1 - 0.4 11.0 2.1 18 5.8 0.0 4.0 5 0 0 5 5 5 0 Invasin, domain 3 SCA7 PF08313.12 KFQ95304.1 - 3.8e-28 97.2 4.1 6.8e-28 96.4 2.3 2.3 2 0 0 2 2 2 1 SCA7, zinc-binding domain OrsD PF12013.8 KFQ95304.1 - 0.046 14.2 0.6 0.2 12.1 0.6 2.1 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D RINT1_TIP1 PF04437.13 KFQ95305.1 - 4.4e-134 448.1 13.8 4.4e-134 448.1 13.8 2.0 2 1 0 3 3 3 1 RINT-1 / TIP-1 family DUF948 PF06103.11 KFQ95305.1 - 0.12 12.6 2.3 3.5 8.0 0.9 3.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TruD PF01142.18 KFQ95306.1 - 1e-70 238.7 0.0 4.1e-65 220.2 0.0 2.7 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Pkinase PF00069.25 KFQ95307.1 - 5.8e-35 120.9 6.2 4.8e-22 78.6 0.2 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ95307.1 - 1.3e-12 47.6 0.1 5.9e-09 35.6 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFQ95307.1 - 0.0069 15.2 0.2 0.0069 15.2 0.2 2.1 1 1 0 2 2 2 1 Fungal protein kinase L_HMGIC_fpl PF10242.9 KFQ95308.1 - 9e-30 104.2 4.9 9.8e-30 104.1 4.9 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein EVC2_like PF12297.8 KFQ95308.1 - 0.22 10.2 1.2 0.23 10.1 1.2 1.0 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Claudin_2 PF13903.6 KFQ95308.1 - 1.1 9.0 12.3 0.48 10.1 9.6 1.7 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2701 PF10857.8 KFQ95308.1 - 1.9 8.6 5.5 3 7.9 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2701) ORC5_C PF14630.6 KFQ95309.1 - 2.4e-48 165.1 0.6 3.6e-48 164.5 0.1 1.5 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 KFQ95309.1 - 5.4e-16 59.5 0.0 8.9e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFQ95309.1 - 5.3e-10 39.7 0.2 3.5e-09 37.1 0.1 2.0 2 0 0 2 2 2 1 AAA domain Kinesin PF00225.23 KFQ95309.1 - 0.0018 17.3 0.4 0.0039 16.1 0.4 1.5 1 1 0 1 1 1 1 Kinesin motor domain AAA_24 PF13479.6 KFQ95309.1 - 0.0042 16.8 0.0 0.007 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KFQ95309.1 - 0.0048 16.9 0.0 0.009 16.0 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Microtub_bd PF16796.5 KFQ95309.1 - 0.0098 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding AAA PF00004.29 KFQ95309.1 - 0.024 15.1 0.0 0.054 13.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KFQ95309.1 - 0.025 14.6 0.3 0.53 10.3 0.3 2.3 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 KFQ95309.1 - 0.025 14.1 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PIF1 PF05970.14 KFQ95309.1 - 0.043 13.0 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 PIF1-like helicase Bac_DnaA PF00308.18 KFQ95309.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.5 1 1 1 2 2 2 0 Bacterial dnaA protein CPT PF07931.12 KFQ95309.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NB-ARC PF00931.22 KFQ95309.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Sulfate_transp PF00916.20 KFQ95310.1 - 1.8e-116 389.0 26.1 2.5e-116 388.6 26.1 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFQ95310.1 - 7e-27 93.4 0.0 1.4e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 STAS domain AAA PF00004.29 KFQ95311.1 - 1.4e-40 138.8 0.0 5.8e-40 136.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFQ95311.1 - 7.6e-09 35.2 0.1 1.7e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KFQ95311.1 - 5e-05 23.6 0.0 0.0054 17.0 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KFQ95311.1 - 0.00039 20.4 0.1 0.0021 18.1 0.1 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFQ95311.1 - 0.0013 19.1 0.1 0.027 14.9 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KFQ95311.1 - 0.0035 17.5 0.0 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KFQ95311.1 - 0.0037 16.5 0.0 0.011 14.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KFQ95311.1 - 0.0071 16.1 0.0 0.019 14.7 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KFQ95311.1 - 0.012 15.8 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFQ95311.1 - 0.013 15.7 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFQ95311.1 - 0.017 15.6 0.0 0.048 14.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 KFQ95311.1 - 0.019 14.5 0.0 0.045 13.3 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 KFQ95311.1 - 0.058 13.5 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 KFQ95311.1 - 0.06 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KFQ95311.1 - 0.071 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 KFQ95311.1 - 0.073 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 KFQ95311.1 - 0.074 12.8 0.3 0.76 9.5 0.0 2.5 3 1 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 KFQ95311.1 - 0.09 13.2 0.0 0.29 11.5 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_3 PF07726.11 KFQ95311.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KFQ95311.1 - 0.15 12.1 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KFQ95311.1 - 0.16 11.7 0.0 0.42 10.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain RAC_head PF16717.5 KFQ95312.1 - 6.6e-23 81.5 9.0 6.6e-23 81.5 9.0 4.4 5 2 0 5 5 5 1 Ribosome-associated complex head domain Myb_DNA-binding PF00249.31 KFQ95312.1 - 2.3e-20 72.5 0.2 1.4e-11 44.4 0.1 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain DnaJ PF00226.31 KFQ95312.1 - 3.1e-15 56.0 0.1 3.1e-15 56.0 0.1 2.8 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-bind_6 PF13921.6 KFQ95312.1 - 3.2e-10 40.1 1.2 7e-06 26.2 0.1 3.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain GHBP PF12772.7 KFQ95312.1 - 0.86 9.1 16.9 0.19 11.2 12.2 2.5 1 1 1 2 2 2 0 Growth hormone receptor binding Peptidase_M16 PF00675.20 KFQ95313.1 - 2e-56 190.1 0.2 3.1e-56 189.5 0.2 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFQ95313.1 - 1.4e-39 136.0 0.0 9.2e-39 133.3 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain Lactamase_B_2 PF12706.7 KFQ95314.1 - 1.4e-37 129.2 0.0 1.9e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KFQ95314.1 - 7.9e-13 48.6 0.0 1.2e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KFQ95314.1 - 0.014 15.4 0.0 0.052 13.5 0.0 1.9 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Arm_2 PF04826.13 KFQ95315.1 - 1.3e-69 234.5 7.8 1.4e-69 234.4 7.8 1.0 1 0 0 1 1 1 1 Armadillo-like Arm PF00514.23 KFQ95315.1 - 1.6e-08 34.3 1.7 0.041 13.9 0.1 3.5 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KFQ95315.1 - 5.7e-05 23.0 0.1 0.033 14.4 0.0 3.3 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 KFQ95315.1 - 0.00053 20.3 0.1 0.11 12.9 0.0 2.3 2 1 0 2 2 2 1 HEAT repeats Cnd1 PF12717.7 KFQ95315.1 - 0.00068 19.7 1.0 0.0052 16.8 1.0 1.9 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KFQ95315.1 - 0.005 17.3 0.3 3.1 8.4 0.0 2.9 3 1 1 4 4 4 2 HEAT-like repeat UME PF08064.13 KFQ95315.1 - 0.0063 16.4 0.7 0.49 10.3 0.0 2.3 1 1 1 2 2 2 1 UME (NUC010) domain Cnd3 PF12719.7 KFQ95315.1 - 0.011 14.9 1.1 0.049 12.8 0.6 1.9 1 1 1 2 2 2 0 Nuclear condensing complex subunits, C-term domain Atx10homo_assoc PF09759.9 KFQ95315.1 - 0.066 13.2 2.0 0.28 11.2 0.7 2.5 1 1 1 2 2 2 0 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.8 KFQ95315.1 - 0.51 10.3 4.1 0.62 10.0 1.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3361) LRR_6 PF13516.6 KFQ95316.1 - 4.7e-24 82.4 20.8 0.057 13.5 0.0 14.0 15 0 0 15 15 15 6 Leucine Rich repeat LRR_4 PF12799.7 KFQ95316.1 - 7.3e-16 58.0 16.1 0.0013 19.0 0.0 9.2 3 3 10 13 13 13 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFQ95316.1 - 1.4e-09 37.6 11.9 0.0005 19.8 0.0 5.7 5 2 2 7 7 7 2 Leucine rich repeat LRR_1 PF00560.33 KFQ95316.1 - 6.1e-07 29.1 20.7 8.3 7.4 0.0 12.1 14 1 0 14 14 14 2 Leucine Rich Repeat F-box-like PF12937.7 KFQ95316.1 - 2.5e-05 24.1 1.0 5.9e-05 22.9 1.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFQ95316.1 - 0.00052 19.8 0.4 0.0018 18.1 0.4 2.0 1 0 0 1 1 1 1 F-box domain SAM_Ste50p PF09235.10 KFQ95316.1 - 0.09 13.0 14.5 33 4.8 0.2 6.7 6 1 1 7 7 7 0 Ste50p, sterile alpha motif LRR_8 PF13855.6 KFQ95317.1 - 4.5e-28 96.8 19.8 5.7e-12 45.2 4.5 4.2 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFQ95317.1 - 4.9e-14 52.2 23.7 3.6e-06 27.2 3.8 4.9 3 1 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFQ95317.1 - 9e-13 48.3 0.5 1.1e-05 25.4 0.1 2.3 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFQ95317.1 - 1.6e-11 44.0 7.6 2.3e-05 23.9 0.2 2.6 2 1 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFQ95317.1 - 0.00015 21.8 15.5 3.6 8.5 0.5 6.9 7 1 1 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.6 KFQ95317.1 - 0.0019 18.1 16.1 3.8 7.8 1.1 5.6 5 0 0 5 5 5 2 Leucine Rich repeat LRRCT PF01463.24 KFQ95317.1 - 0.02 15.4 0.0 2.5 8.8 0.0 2.9 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain DUF4097 PF13349.6 KFQ95319.1 - 6.2e-09 35.6 22.2 2.1e-06 27.3 15.2 2.9 1 1 1 2 2 2 2 Putative adhesin DUF2807 PF10988.8 KFQ95319.1 - 0.017 14.9 0.9 0.017 14.9 0.9 2.8 1 1 0 2 2 2 0 Putative auto-transporter adhesin, head GIN domain HtaA PF04213.13 KFQ95319.1 - 0.097 13.2 2.8 0.13 12.8 1.1 1.9 2 1 0 2 2 2 0 Htaa DUF948 PF06103.11 KFQ95320.1 - 2.6 8.4 31.1 1.8 8.9 1.8 6.4 6 0 0 6 6 6 0 Bacterial protein of unknown function (DUF948) Fibrinogen_C PF00147.18 KFQ95321.1 - 2.1e-89 299.1 10.1 2.8e-89 298.7 10.1 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain FlaC_arch PF05377.11 KFQ95321.1 - 0.0018 18.6 5.4 0.0027 18.1 2.0 2.4 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) COLFI PF01410.18 KFQ95321.1 - 0.0098 15.2 0.2 0.023 14.0 0.1 1.7 1 1 0 1 1 1 1 Fibrillar collagen C-terminal domain TPR_MLP1_2 PF07926.12 KFQ95321.1 - 0.055 13.5 4.2 3.7 7.6 0.3 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N PF09744.9 KFQ95321.1 - 0.095 12.9 6.6 0.15 12.2 6.6 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Med9 PF07544.13 KFQ95321.1 - 0.11 12.6 7.2 0.24 11.5 0.7 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 BORCS6 PF10157.9 KFQ95321.1 - 0.19 12.0 2.6 0.4 10.9 2.6 1.6 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 6 Laminin_II PF06009.12 KFQ95321.1 - 0.21 11.6 7.1 0.14 12.2 2.9 2.1 2 0 0 2 2 2 0 Laminin Domain II MutS_II PF05188.17 KFQ95321.1 - 0.23 11.7 1.2 0.79 10.0 0.2 2.3 2 1 1 3 3 3 0 MutS domain II YscO PF07321.12 KFQ95321.1 - 0.24 11.4 4.1 0.82 9.6 0.6 2.2 2 0 0 2 2 2 0 Type III secretion protein YscO BLOC1_2 PF10046.9 KFQ95321.1 - 0.29 11.4 6.2 1.9 8.8 2.0 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Exonuc_VII_L PF02601.15 KFQ95321.1 - 0.32 10.5 2.6 0.49 9.9 2.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Alanine_zipper PF11839.8 KFQ95321.1 - 0.35 11.3 1.2 30 5.1 0.1 2.3 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein Prefoldin PF02996.17 KFQ95321.1 - 0.36 10.7 5.8 6.9 6.6 0.5 2.4 2 0 0 2 2 2 0 Prefoldin subunit LPP PF04728.13 KFQ95321.1 - 0.52 10.7 6.0 3.7 8.0 0.5 2.8 3 0 0 3 3 2 0 Lipoprotein leucine-zipper DUF1664 PF07889.12 KFQ95321.1 - 0.53 10.3 3.0 1.6 8.8 0.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Csm1_N PF18504.1 KFQ95321.1 - 0.95 9.8 8.6 1 9.7 1.3 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain EMP24_GP25L PF01105.24 KFQ95321.1 - 1.2 9.0 5.3 1.2 9.1 1.8 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Uds1 PF15456.6 KFQ95321.1 - 1.3 9.2 4.7 2.8 8.1 4.7 1.5 1 0 0 1 1 1 0 Up-regulated During Septation SOGA PF11365.8 KFQ95321.1 - 1.8 9.7 5.9 7.6 7.7 5.9 2.0 1 1 0 1 1 1 0 Protein SOGA CLZ PF16526.5 KFQ95321.1 - 2 8.9 5.6 1.2 9.5 1.3 2.7 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 KFQ95321.1 - 3.1 8.3 5.3 4.6 7.8 1.6 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PRKG1_interact PF15898.5 KFQ95321.1 - 3.5 8.6 9.6 20 6.1 9.3 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain GSAP-16 PF14959.6 KFQ95322.1 - 6.8e-41 138.5 0.1 2.1e-40 137.0 0.1 1.9 1 0 0 1 1 1 1 gamma-Secretase-activating protein C-term Y_phosphatase PF00102.27 KFQ95323.1 - 8.5e-82 274.2 0.2 1.2e-81 273.7 0.2 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFQ95323.1 - 4.4e-05 23.6 0.0 7.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KFQ95323.1 - 0.011 15.5 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain UBN_AB PF14075.6 KFQ95323.1 - 0.018 14.8 0.4 0.043 13.5 0.4 1.6 1 0 0 1 1 1 0 Ubinuclein conserved middle domain ER-remodelling PF14755.6 KFQ95323.1 - 0.23 11.8 6.4 0.37 11.1 3.7 2.6 2 0 0 2 2 2 0 Intracellular membrane remodeller JmjC PF02373.22 KFQ95325.1 - 0.44 11.0 0.0 0.44 11.0 0.0 1.9 2 0 0 2 2 2 0 JmjC domain, hydroxylase Tmemb_185A PF10269.9 KFQ95326.1 - 1.1e-13 51.4 3.0 1.4e-13 51.1 3.0 1.2 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein DUF3522 PF12036.8 KFQ95326.1 - 0.0071 16.6 3.6 0.0097 16.2 3.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3522) CoA_binding_3 PF13727.6 KFQ95326.1 - 4.6 7.2 12.1 0.16 12.0 5.6 1.7 1 1 1 2 2 2 0 CoA-binding domain Phtf-FEM1B_bdg PF12129.8 KFQ95327.1 - 3.5e-63 212.1 0.3 3.5e-63 212.1 0.3 2.1 2 1 1 3 3 3 1 Male germ-cell putative homeodomain transcription factor PDZ PF00595.24 KFQ95328.1 - 2.3e-61 204.1 9.8 3.5e-15 56.1 0.0 5.6 5 0 0 5 5 5 5 PDZ domain PDZ_6 PF17820.1 KFQ95328.1 - 7.3e-49 163.4 13.1 3.1e-11 43.0 0.1 5.3 5 0 0 5 5 5 5 PDZ domain PDZ_2 PF13180.6 KFQ95328.1 - 3.6e-25 88.1 0.1 4.1e-05 23.8 0.0 5.4 5 0 0 5 5 5 5 PDZ domain MAGI_u1 PF16663.5 KFQ95328.1 - 3.3e-23 81.5 2.5 1.1e-22 79.8 2.5 2.0 1 0 0 1 1 1 1 Unstructured region on MAGI WW PF00397.26 KFQ95328.1 - 3.5e-16 59.0 7.2 1.8e-09 37.5 0.3 3.2 3 0 0 3 3 3 2 WW domain Guanylate_kin PF00625.21 KFQ95328.1 - 1.5e-08 34.5 0.0 2.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase Tricorn_PDZ PF14685.6 KFQ95328.1 - 7.8e-07 29.0 2.2 1.8 8.6 0.0 5.1 5 0 0 5 5 5 2 Tricorn protease PDZ domain MAGI_u5 PF16666.5 KFQ95328.1 - 0.001 19.2 3.4 0.001 19.2 3.4 4.8 5 0 0 5 5 5 1 Unstructured region on MAGI PDZ_4 PF17816.1 KFQ95328.1 - 0.02 15.3 0.0 37 4.8 0.0 3.8 3 0 0 3 3 3 0 PDZ domain G-alpha PF00503.20 KFQ95330.1 - 2.8e-120 401.7 2.7 3.5e-120 401.4 2.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFQ95330.1 - 5.9e-16 58.4 0.4 1.9e-11 43.7 0.2 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KFQ95330.1 - 0.0014 18.8 0.5 2.2 8.5 0.1 2.8 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KFQ95330.1 - 0.0036 16.7 2.9 0.4 10.0 0.5 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region TniB PF05621.11 KFQ95330.1 - 0.0039 16.6 0.0 0.0063 16.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_16 PF13191.6 KFQ95330.1 - 0.0068 16.8 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KFQ95330.1 - 0.12 12.2 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CD36 PF01130.21 KFQ95331.1 - 8.7e-145 482.8 0.0 9.9e-145 482.6 0.0 1.0 1 0 0 1 1 1 1 CD36 family Sema PF01403.19 KFQ95332.1 - 1e-147 492.4 0.0 1.5e-147 491.9 0.0 1.2 1 0 0 1 1 1 1 Sema domain I-set PF07679.16 KFQ95332.1 - 6.6e-06 26.1 0.2 1.9e-05 24.6 0.1 1.9 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ95332.1 - 1.3e-05 25.7 0.1 8.1e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain PSI PF01437.25 KFQ95332.1 - 0.00088 19.8 7.5 0.0026 18.3 7.5 1.9 1 0 0 1 1 1 1 Plexin repeat ig PF00047.25 KFQ95332.1 - 0.0057 16.8 0.0 0.019 15.1 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFQ95332.1 - 0.0075 16.6 0.0 0.022 15.1 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFQ95332.1 - 0.01 16.0 0.5 0.2 11.8 0.1 3.0 2 1 0 2 2 2 0 Immunoglobulin V-set domain Kringle PF00051.18 KFQ95333.1 - 1.6e-110 361.6 40.6 1.7e-29 101.9 6.7 4.5 4 0 0 4 4 4 4 Kringle domain Trypsin PF00089.26 KFQ95333.1 - 6.7e-48 163.4 0.0 1.2e-47 162.6 0.0 1.4 1 0 0 1 1 1 1 Trypsin PAN_1 PF00024.26 KFQ95333.1 - 4.1e-10 39.5 1.2 1.3e-09 37.9 1.2 1.9 1 0 0 1 1 1 1 PAN domain DUF1986 PF09342.11 KFQ95333.1 - 0.0012 19.2 0.0 0.0026 18.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) VGCC_alpha2 PF08473.11 KFQ95334.1 - 3.7e-208 691.6 1.3 5.3e-208 691.1 1.3 1.2 1 0 0 1 1 1 1 Neuronal voltage-dependent calcium channel alpha 2acd VWA_N PF08399.11 KFQ95334.1 - 6.1e-36 123.6 0.1 1.8e-35 122.1 0.1 1.9 1 0 0 1 1 1 1 VWA N-terminal VWA PF00092.28 KFQ95334.1 - 4e-22 79.3 0.4 6.9e-22 78.5 0.4 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFQ95334.1 - 5.6e-14 52.4 0.0 9.1e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFQ95334.1 - 7.2e-11 42.7 0.2 1.9e-10 41.4 0.2 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain dCache_1 PF02743.18 KFQ95334.1 - 2.2e-10 40.8 7.3 1e-09 38.6 0.1 3.5 3 1 0 3 3 3 1 Cache domain vWA-TerF-like PF10138.9 KFQ95334.1 - 0.0032 17.6 0.4 0.0063 16.6 0.4 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus PsbP PF01789.16 KFQ95336.1 - 0.041 14.0 0.0 0.046 13.9 0.0 1.1 1 0 0 1 1 1 0 PsbP C2 PF00168.30 KFQ95337.1 - 6.3e-39 132.4 0.3 1.2e-24 86.6 0.0 2.9 2 0 0 2 2 2 2 C2 domain PDZ PF00595.24 KFQ95337.1 - 8.7e-06 26.0 0.4 2.3e-05 24.6 0.4 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFQ95337.1 - 6.1e-05 22.8 0.0 0.00019 21.2 0.0 1.9 1 0 0 1 1 1 1 PDZ domain GPS2_interact PF15784.5 KFQ95337.1 - 2.9 8.4 18.6 0.031 14.7 1.7 3.9 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain Sema PF01403.19 KFQ95339.1 - 4e-146 487.1 0.0 5.7e-146 486.6 0.0 1.2 1 0 0 1 1 1 1 Sema domain ig PF00047.25 KFQ95339.1 - 3.4e-05 23.9 0.0 6.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFQ95339.1 - 0.00012 22.2 0.7 0.0006 20.0 0.0 2.5 2 1 0 2 2 2 1 Immunoglobulin V-set domain PSI PF01437.25 KFQ95339.1 - 0.0032 18.0 5.4 0.0032 18.0 5.4 2.1 2 0 0 2 2 2 1 Plexin repeat Ig_2 PF13895.6 KFQ95339.1 - 0.12 12.7 0.0 1.4 9.3 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain Sema PF01403.19 KFQ95340.1 - 1.3e-160 534.8 0.0 1.8e-160 534.4 0.0 1.2 1 0 0 1 1 1 1 Sema domain ig PF00047.25 KFQ95340.1 - 9.5e-08 32.1 0.0 2.6e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFQ95340.1 - 2e-05 24.7 0.1 9.5e-05 22.5 0.1 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFQ95340.1 - 0.001 19.6 0.0 0.0037 17.8 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain PSI PF01437.25 KFQ95340.1 - 0.0024 18.4 6.9 0.0024 18.4 6.9 2.0 2 0 0 2 2 2 1 Plexin repeat Ig_2 PF13895.6 KFQ95340.1 - 0.0027 18.0 0.0 0.01 16.1 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ95340.1 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_6 PF18452.1 KFQ95340.1 - 0.04 13.5 0.0 0.091 12.3 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain RVT_1 PF00078.27 KFQ95341.1 - 0.0087 15.6 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LIM_bind PF01803.16 KFQ95344.1 - 8.7e-35 120.4 9.4 4.8e-23 81.9 0.4 2.9 2 1 1 3 3 3 2 LIM-domain binding protein LID PF17916.1 KFQ95344.1 - 1.4e-18 66.2 2.5 2.3e-18 65.5 2.5 1.4 1 0 0 1 1 1 1 LIM interaction domain (LID) DTHCT PF08070.11 KFQ95344.1 - 0.03 15.1 2.9 0.03 15.1 2.9 1.7 2 0 0 2 2 2 0 DTHCT (NUC029) region zf-DNL PF05180.12 KFQ95344.1 - 0.065 13.2 0.2 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 DNL zinc finger Coilin_N PF15862.5 KFQ95344.1 - 0.14 12.0 2.6 0.28 11.0 2.6 1.5 1 0 0 1 1 1 0 Coilin N-terminus DUF747 PF05346.11 KFQ95345.1 - 8.5e-108 360.6 19.5 1.1e-107 360.2 19.5 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family DASH_Dad4 PF08650.10 KFQ95345.1 - 0.04 13.9 3.9 0.25 11.4 2.2 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad4 Prominin PF05478.11 KFQ95346.1 - 2.1e-258 859.5 13.4 2.5e-258 859.3 13.4 1.0 1 0 0 1 1 1 1 Prominin Tweety PF04906.13 KFQ95346.1 - 0.013 14.2 0.5 0.013 14.2 0.5 3.4 2 1 0 3 3 3 0 Tweety Cyt_bd_oxida_II PF02322.15 KFQ95346.1 - 0.074 12.4 4.4 5.4 6.3 2.0 2.2 2 0 0 2 2 2 0 Cytochrome bd terminal oxidase subunit II DUF1218 PF06749.12 KFQ95346.1 - 0.095 13.2 13.1 1.1 9.8 2.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) ALIX_LYPXL_bnd PF13949.6 KFQ95346.1 - 0.12 11.6 0.5 0.38 10.0 0.5 1.8 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV ATP-synt_I PF03899.15 KFQ95346.1 - 0.55 10.6 0.1 0.55 10.6 0.1 3.4 3 1 0 3 3 3 0 ATP synthase I chain Claudin_2 PF13903.6 KFQ95346.1 - 1.2 8.9 8.4 11 5.8 4.6 2.6 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF948 PF06103.11 KFQ95346.1 - 5.8 7.2 10.2 13 6.1 0.4 4.7 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) FGF-BP1 PF06473.12 KFQ95347.1 - 1.1e-51 175.8 0.5 1.3e-51 175.6 0.5 1.1 1 0 0 1 1 1 1 FGF binding protein 1 (FGF-BP1) FGF-BP1 PF06473.12 KFQ95348.1 - 1.7e-63 214.5 17.8 3e-63 213.7 17.8 1.4 1 1 0 1 1 1 1 FGF binding protein 1 (FGF-BP1) Rib_hydrolayse PF02267.17 KFQ95349.1 - 1.5e-103 345.4 0.6 1.8e-103 345.2 0.6 1.0 1 0 0 1 1 1 1 ADP-ribosyl cyclase DUF3932 PF13068.6 KFQ95349.1 - 0.046 14.0 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3932) Pilin_N PF07790.11 KFQ95349.1 - 0.13 13.2 0.3 0.25 12.3 0.3 1.5 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal TMEM119 PF15724.5 KFQ95349.1 - 0.18 11.9 0.3 0.26 11.3 0.3 1.2 1 0 0 1 1 1 0 TMEM119 family Rib_hydrolayse PF02267.17 KFQ95350.1 - 3e-17 62.8 0.0 3.2e-17 62.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosyl cyclase F-box-like PF12937.7 KFQ95351.1 - 4.5e-15 55.3 0.1 1.5e-14 53.6 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KFQ95351.1 - 9e-11 41.8 2.2 0.0001 22.6 0.0 3.5 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFQ95351.1 - 1.3e-10 40.5 3.6 0.0078 16.2 0.0 4.5 4 0 0 4 4 4 3 Leucine Rich repeat F-box PF00646.33 KFQ95351.1 - 2.6e-10 39.9 1.5 1e-09 38.0 0.0 2.7 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.33 KFQ95351.1 - 1.7e-06 27.8 0.8 1.3 9.9 0.0 5.3 4 0 0 4 4 4 2 Leucine Rich Repeat Hemerythrin PF01814.23 KFQ95351.1 - 9.3e-06 26.3 5.5 0.0003 21.4 0.5 2.1 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain LRR_8 PF13855.6 KFQ95351.1 - 0.00082 19.1 1.1 0.58 10.0 0.1 3.4 2 1 0 2 2 2 2 Leucine rich repeat F-box_4 PF15966.5 KFQ95351.1 - 0.013 15.4 0.1 0.064 13.1 0.0 2.3 2 0 0 2 2 2 0 F-box FTCD_C PF04961.12 KFQ95351.1 - 0.4 10.4 2.4 1.9 8.2 1.5 2.2 1 1 0 2 2 2 0 Formiminotransferase-cyclodeaminase DUF5523 PF17661.1 KFQ95352.1 - 2.1e-95 319.3 11.8 2.1e-95 319.3 11.8 2.5 2 0 0 2 2 2 1 Family of unknown function (DUF5523) CC2D2AN-C2 PF15625.6 KFQ95352.1 - 1.7e-61 207.0 0.1 3.2e-61 206.1 0.1 1.5 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain C2 PF00168.30 KFQ95352.1 - 5.2e-09 36.3 0.1 2.2e-05 24.7 0.0 2.7 2 0 0 2 2 2 2 C2 domain DUF3987 PF13148.6 KFQ95352.1 - 0.0025 16.9 5.8 0.006 15.6 5.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) Perilipin PF03036.16 KFQ95352.1 - 0.47 9.4 5.8 0.98 8.4 5.8 1.4 1 0 0 1 1 1 0 Perilipin family C1q PF00386.21 KFQ95353.1 - 9.7e-39 132.5 0.0 1.3e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFQ95353.1 - 5.3e-16 58.1 58.5 4.9e-09 35.8 25.8 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) BclA_C PF18573.1 KFQ95353.1 - 0.021 14.7 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 BclA C-terminal domain RRM_7 PF16367.5 KFQ95355.1 - 3e-38 129.8 0.0 2.3e-36 123.8 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif CEBP_ZZ PF16366.5 KFQ95355.1 - 5.1e-21 74.7 5.2 1.2e-20 73.4 5.2 1.7 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 KFQ95355.1 - 4.4e-12 45.6 0.0 8.1e-07 28.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-U1 PF06220.12 KFQ95355.1 - 0.078 12.8 0.3 0.22 11.3 0.3 1.7 1 0 0 1 1 1 0 U1 zinc finger HSP20 PF00011.21 KFQ95355.1 - 0.15 12.2 0.0 0.51 10.5 0.0 1.8 2 0 0 2 2 2 0 Hsp20/alpha crystallin family zf-B_box PF00643.24 KFQ95355.1 - 0.4 10.9 5.9 0.95 9.7 5.9 1.5 1 0 0 1 1 1 0 B-box zinc finger LAP1C PF05609.12 KFQ95357.1 - 1.7 7.7 18.1 1.9 7.5 18.1 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Ras PF00071.22 KFQ95358.1 - 3.6e-41 140.5 0.3 4.8e-41 140.1 0.3 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ95358.1 - 1.4e-28 99.5 0.1 2.3e-28 98.8 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ95358.1 - 1.9e-12 47.0 0.1 2.4e-12 46.7 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFQ95358.1 - 4.3e-05 23.0 0.3 5.5e-05 22.6 0.3 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 KFQ95358.1 - 0.077 12.7 0.1 0.19 11.4 0.1 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 KFQ95358.1 - 0.097 12.4 0.8 0.64 9.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain Sulfotransfer_1 PF00685.27 KFQ95359.1 - 4.7e-38 131.2 0.5 6.5e-38 130.7 0.5 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFQ95359.1 - 8.7e-15 55.7 0.3 2.7e-09 37.8 0.1 2.4 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFQ95359.1 - 0.0018 18.2 0.5 0.0047 16.9 0.5 1.8 1 1 0 1 1 1 1 Sulfotransferase family zf-H2C2_5 PF13909.6 KFQ95361.1 - 8.7e-06 25.4 1.1 8.7e-06 25.4 1.1 4.3 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KFQ95361.1 - 1.8e-05 24.9 0.5 1.8e-05 24.9 0.5 5.6 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ95361.1 - 0.00027 21.2 29.8 0.23 12.0 0.1 5.4 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 KFQ95361.1 - 0.6 9.8 10.2 3 7.6 0.3 4.9 4 0 0 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain TRH PF05438.12 KFQ95363.1 - 3.1e-99 331.2 12.1 3.3e-96 321.3 8.1 2.0 2 0 0 2 2 2 2 Thyrotropin-releasing hormone (TRH) Med2 PF11214.8 KFQ95363.1 - 0.0067 16.6 0.2 0.025 14.7 0.0 2.0 2 0 0 2 2 2 1 Mediator complex subunit 2 Prothymosin PF03247.14 KFQ95363.1 - 1.1 9.7 9.0 0.13 12.7 0.6 2.8 3 0 0 3 3 3 0 Prothymosin/parathymosin family NPF PF16601.5 KFQ95364.1 - 3.5e-55 187.4 16.7 9.5e-55 186.0 16.7 1.8 1 0 0 1 1 1 1 Rabosyn-5 repeating NPF sequence-motif Rbsn PF11464.8 KFQ95364.1 - 1.5e-27 95.0 15.5 1.8e-15 56.4 3.2 3.2 3 0 0 3 3 3 2 Rabenosyn Rab binding domain FYVE PF01363.21 KFQ95364.1 - 8.3e-18 64.3 6.6 2.1e-17 63.0 6.6 1.8 1 0 0 1 1 1 1 FYVE zinc finger RNA_POL_M_15KD PF02150.16 KFQ95364.1 - 0.037 13.9 5.9 0.036 13.9 1.2 2.7 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-Di19 PF05605.12 KFQ95364.1 - 0.042 14.1 0.1 0.042 14.1 0.1 2.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding TerY_C PF15616.6 KFQ95364.1 - 0.073 13.2 0.8 0.22 11.6 0.1 2.2 2 0 0 2 2 2 0 TerY-C metal binding domain IBR PF01485.21 KFQ95364.1 - 0.24 11.7 6.2 0.07 13.4 1.8 2.2 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zinc_ribbon_9 PF14369.6 KFQ95364.1 - 0.49 10.7 6.6 0.25 11.6 0.3 3.1 3 0 0 3 3 3 0 zinc-ribbon zinc_ribbon_12 PF11331.8 KFQ95364.1 - 0.53 10.1 3.2 0.32 10.8 0.2 2.2 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-C2H2_9 PF16293.5 KFQ95364.1 - 0.6 10.0 3.8 2 8.3 0.0 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) C1_1 PF00130.22 KFQ95364.1 - 2.8 7.9 9.5 0.79 9.7 3.6 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HypA PF01155.19 KFQ95364.1 - 4.6 7.3 9.6 0.37 10.8 0.4 3.1 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KFQ95364.1 - 6.9 6.8 11.4 0.41 10.7 2.7 2.8 3 0 0 3 3 3 0 Double zinc ribbon L51_S25_CI-B8 PF05047.16 KFQ95365.1 - 3.9e-13 49.1 0.3 6.5e-13 48.4 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Hormone_recep PF00104.30 KFQ95366.1 - 6.3e-46 156.6 0.8 1.1e-45 155.7 0.8 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFQ95366.1 - 5.6e-32 110.0 16.3 1.1e-31 109.1 16.3 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) FAA_hydro_N_2 PF18288.1 KFQ95366.1 - 0.045 14.2 0.9 0.55 10.7 0.1 3.1 2 2 0 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 SelK_SelG PF10961.8 KFQ95368.1 - 2.9e-29 101.5 0.5 3.3e-29 101.3 0.5 1.0 1 0 0 1 1 1 1 Selenoprotein SelK_SelG Actin PF00022.19 KFQ95369.1 - 1.5e-32 112.8 0.0 6.9e-15 54.6 0.0 3.4 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 KFQ95369.1 - 1.5e-15 57.3 0.1 6.2e-08 32.2 0.1 2.1 2 0 0 2 2 2 2 Putative actin-like family GMC_oxred_N PF00732.19 KFQ95370.1 - 5.2e-98 328.1 0.0 6.9e-98 327.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFQ95370.1 - 6.4e-40 137.0 0.0 1.1e-39 136.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KFQ95370.1 - 2.9e-06 26.6 0.0 0.033 13.3 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KFQ95370.1 - 9.8e-06 25.4 0.0 1.5e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFQ95370.1 - 2.1e-05 23.8 0.0 3.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KFQ95370.1 - 0.0018 17.6 0.0 2 7.6 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFQ95370.1 - 0.0027 17.9 0.0 0.0082 16.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFQ95370.1 - 0.0074 15.6 0.0 0.032 13.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Ion_trans PF00520.31 KFQ95371.1 - 1.5e-252 833.2 86.4 1e-70 237.8 14.2 4.1 4 0 0 4 4 4 4 Ion transport protein CAC1F_C PF16885.5 KFQ95371.1 - 8.2e-75 252.8 2.2 8.2e-75 252.8 2.2 2.5 2 0 0 2 2 2 1 Voltage-gated calcium channel subunit alpha, C-term Ca_chan_IQ PF08763.11 KFQ95371.1 - 7e-31 106.3 0.2 1.6e-30 105.1 0.2 1.7 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain GPHH PF16905.5 KFQ95371.1 - 1.1e-28 98.7 0.1 3.4e-28 97.2 0.1 1.9 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 KFQ95371.1 - 8.5e-11 41.2 26.0 5.1e-10 38.6 7.2 9.5 7 3 2 9 9 9 3 Polycystin cation channel DUF4834 PF16118.5 KFQ95371.1 - 0.039 14.9 0.1 0.039 14.9 0.1 8.9 9 0 0 9 9 9 0 Domain of unknown function (DUF4834) Rer1 PF03248.13 KFQ95371.1 - 0.053 13.3 9.3 0.31 10.7 2.5 4.3 4 0 0 4 4 4 0 Rer1 family DUF5305 PF17231.2 KFQ95371.1 - 0.066 12.6 0.4 3.4 7.0 0.0 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5305) NARP1 PF12569.8 KFQ95371.1 - 1.9 7.3 6.5 3.9 6.3 6.5 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 EphA2_TM PF14575.6 KFQ95371.1 - 7.1 7.6 7.1 32 5.5 0.1 5.4 6 0 0 6 6 6 0 Ephrin type-A receptor 2 transmembrane domain DCP1 PF06058.13 KFQ95372.1 - 7.9e-27 93.5 0.0 1.8e-26 92.4 0.0 1.7 1 0 0 1 1 1 1 Dcp1-like decapping family mRNA_decap_C PF16741.5 KFQ95372.1 - 9.1e-22 76.1 1.4 1.8e-21 75.1 1.4 1.6 1 0 0 1 1 1 1 mRNA-decapping enzyme C-terminus Transketolase_N PF00456.21 KFQ95373.1 - 1.1e-44 152.8 0.0 2.1e-44 151.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KFQ95373.1 - 2.5e-40 138.1 0.0 5.2e-40 137.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFQ95373.1 - 2.9e-33 114.4 0.3 5.8e-33 113.4 0.3 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 KFQ95373.1 - 3e-07 29.7 0.0 8.4e-07 28.2 0.0 1.8 2 0 0 2 2 2 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KFQ95373.1 - 4e-06 26.7 0.1 0.00014 21.7 0.1 3.2 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KFQ95373.1 - 7.8e-06 25.3 0.0 0.00033 20.0 0.0 2.6 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.10 KFQ95373.1 - 0.004 16.0 0.1 0.017 13.9 0.0 1.8 1 1 1 2 2 2 1 XFP N-terminal domain HECT PF00632.25 KFQ95374.1 - 1.5e-102 343.3 0.0 1.9e-102 342.9 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KFQ95374.1 - 1.3e-50 169.2 28.2 7.2e-13 48.4 2.9 5.2 5 0 0 5 5 5 4 WW domain C2 PF00168.30 KFQ95374.1 - 2.5e-20 72.7 0.1 6e-20 71.5 0.1 1.7 1 0 0 1 1 1 1 C2 domain PhoLip_ATPase_C PF16212.5 KFQ95375.1 - 1.6e-79 267.2 24.0 1.6e-79 267.2 24.0 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFQ95375.1 - 8.3e-26 89.5 5.2 8.3e-26 89.5 5.2 2.1 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KFQ95375.1 - 2.7e-13 49.8 0.0 1.8e-12 47.1 0.0 2.4 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFQ95375.1 - 5.5e-10 39.9 0.9 0.00053 20.3 0.0 3.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFQ95375.1 - 1.3e-09 37.9 0.0 6.5e-09 35.6 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFQ95375.1 - 0.0029 17.4 1.6 0.0029 17.4 1.6 2.9 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase FimH_man-bind PF09160.10 KFQ95375.1 - 0.08 12.6 0.0 3.2 7.4 0.1 2.4 2 0 0 2 2 2 0 FimH, mannose binding ATP-synt_8 PF00895.20 KFQ95375.1 - 2.3 8.7 9.1 4.9 7.7 0.2 3.6 3 0 0 3 3 3 0 ATP synthase protein 8 tRNA-synt_2 PF00152.20 KFQ95376.1 - 4.2e-111 371.0 0.0 6.2e-111 370.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFQ95376.1 - 5.4e-11 42.3 0.0 1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1565 PF07602.11 KFQ95376.1 - 0.014 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) Maff2 PF12750.7 KFQ95376.1 - 0.061 13.1 0.0 14 5.6 0.0 2.5 2 0 0 2 2 2 0 Maff2 family tRNA_anti-like PF12869.7 KFQ95376.1 - 0.07 12.7 0.0 0.19 11.4 0.0 1.6 1 1 0 1 1 1 0 tRNA_anti-like Ferrochelatase PF00762.19 KFQ95377.1 - 3.6e-110 368.0 0.0 4.2e-110 367.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Homeodomain PF00046.29 KFQ95378.1 - 1.6e-11 43.9 1.2 2.3e-11 43.4 1.2 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ95378.1 - 1.5e-05 24.8 0.4 2.9e-05 23.9 0.1 1.6 2 0 0 2 2 2 1 Homeobox KN domain HOCHOB PF17943.1 KFQ95378.1 - 0.032 14.9 0.1 0.049 14.3 0.1 1.2 1 0 0 1 1 1 0 Homeobox-cysteine loop-homeobox PH_3 PF14593.6 KFQ95378.1 - 0.065 13.4 0.6 0.08 13.1 0.6 1.1 1 0 0 1 1 1 0 PH domain WD40 PF00400.32 KFQ95379.1 - 2.1e-20 72.6 15.7 0.00019 22.2 0.1 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ95379.1 - 4.9e-09 36.4 0.0 0.045 14.1 0.0 6.6 4 3 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFQ95379.1 - 0.087 11.8 4.9 2.3 7.1 0.0 3.5 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PITH PF06201.13 KFQ95380.1 - 2.7e-40 138.1 0.0 3.7e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 KFQ95380.1 - 1.2e-13 50.9 0.0 2e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KFQ95380.1 - 0.0087 15.4 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Sad1_UNC PF07738.13 KFQ95380.1 - 0.025 14.6 0.0 0.053 13.5 0.0 1.6 1 1 0 1 1 1 0 Sad1 / UNC-like C-terminal HLH PF00010.26 KFQ95381.1 - 2.4e-11 43.4 1.9 6e-11 42.1 1.2 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain CDC45 PF02724.14 KFQ95381.1 - 0.6 8.3 8.8 0.82 7.9 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Ras PF00071.22 KFQ95382.1 - 5.4e-55 185.4 0.0 6.9e-55 185.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ95382.1 - 2.3e-32 111.7 0.0 3.5e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ95382.1 - 3.6e-13 49.3 0.0 5.7e-13 48.7 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_24 PF13479.6 KFQ95382.1 - 9.4e-05 22.2 0.1 0.059 13.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KFQ95382.1 - 0.00011 22.1 0.1 0.12 12.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFQ95382.1 - 0.00042 20.4 0.0 0.00085 19.4 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFQ95382.1 - 0.0037 16.8 0.0 0.011 15.3 0.0 1.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KFQ95382.1 - 0.012 15.4 0.4 0.21 11.3 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.20 KFQ95382.1 - 0.016 14.4 0.3 3.7 6.6 0.0 2.3 1 1 1 2 2 2 0 G-protein alpha subunit Gtr1_RagA PF04670.12 KFQ95382.1 - 0.059 12.7 0.1 0.15 11.4 0.1 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region CENP-M PF11111.8 KFQ95382.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) AAA_22 PF13401.6 KFQ95382.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.6 1 1 1 2 2 2 0 AAA domain START PF01852.19 KFQ95383.1 - 3.2e-22 79.0 0.0 3.7e-22 78.8 0.0 1.0 1 0 0 1 1 1 1 START domain IMS PF00817.20 KFQ95384.1 - 5e-46 156.4 0.0 9.4e-46 155.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KFQ95384.1 - 2.6e-15 57.2 0.0 5.5e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KFQ95384.1 - 1.6e-05 24.9 0.0 4.8e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif Cdd1 PF11731.8 KFQ95384.1 - 0.0014 18.9 0.0 0.0046 17.2 0.0 1.9 2 0 0 2 2 2 1 Pathogenicity locus DNA_pol_lambd_f PF10391.9 KFQ95384.1 - 0.047 13.5 0.0 0.42 10.5 0.0 2.6 3 0 0 3 3 3 0 Fingers domain of DNA polymerase lambda DUF1805 PF08827.11 KFQ95384.1 - 0.16 12.3 0.0 0.52 10.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) MBDa PF16564.5 KFQ95385.1 - 6.2e-31 106.4 2.6 9.7e-31 105.8 2.6 1.3 1 0 0 1 1 1 1 p55-binding region of Methyl-CpG-binding domain proteins MBD MBD_C PF14048.6 KFQ95385.1 - 3.3e-23 82.2 1.1 5e-23 81.6 0.0 1.8 2 1 0 2 2 2 1 C-terminal domain of methyl-CpG binding protein 2 and 3 MBD PF01429.19 KFQ95385.1 - 8.3e-11 41.4 0.4 1.2e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 Methyl-CpG binding domain RasGAP PF00616.19 KFQ95385.1 - 0.031 14.0 0.0 0.081 12.6 0.1 1.6 1 1 1 2 2 2 0 GTPase-activator protein for Ras-like GTPase Pardaxin PF07425.11 KFQ95385.1 - 0.12 12.0 0.9 0.27 10.9 0.9 1.6 1 0 0 1 1 1 0 Pardaxin fn3 PF00041.21 KFQ95386.1 - 8.6e-79 260.0 20.8 1.4e-15 57.3 0.2 6.4 6 0 0 6 6 6 6 Fibronectin type III domain I-set PF07679.16 KFQ95386.1 - 2.3e-59 197.5 0.0 2.4e-16 59.6 0.0 5.8 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ95386.1 - 4.8e-56 187.3 0.0 8.8e-15 55.1 0.0 6.4 6 0 0 6 6 5 4 Immunoglobulin domain Neogenin_C PF06583.12 KFQ95386.1 - 1.7e-40 139.7 4.3 1.7e-40 139.7 4.3 1.9 2 0 0 2 2 1 1 Neogenin C-terminus ig PF00047.25 KFQ95386.1 - 7.1e-40 135.1 0.0 7e-13 48.6 0.0 5.7 5 0 0 5 5 5 4 Immunoglobulin domain Ig_2 PF13895.6 KFQ95386.1 - 4.3e-39 132.7 0.0 1.4e-11 44.6 0.1 5.2 5 0 0 5 5 5 4 Immunoglobulin domain V-set PF07686.17 KFQ95386.1 - 6.3e-19 68.2 3.1 7.1e-05 22.9 0.6 8.5 7 3 0 7 7 6 3 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 KFQ95386.1 - 2.2e-16 60.2 18.0 0.0035 17.9 0.1 7.1 6 2 0 6 6 6 4 Purple acid Phosphatase, N-terminal domain C2-set_2 PF08205.12 KFQ95386.1 - 1.8e-10 40.8 0.6 0.12 12.4 0.0 5.2 5 0 0 5 5 5 3 CD80-like C2-set immunoglobulin domain Interfer-bind PF09294.10 KFQ95386.1 - 3.8e-09 36.8 0.1 0.48 10.8 0.0 5.2 6 0 0 6 6 5 2 Interferon-alpha/beta receptor, fibronectin type III Ig_5 PF16681.5 KFQ95386.1 - 5e-06 26.8 0.0 1.6 9.2 0.0 4.4 4 0 0 4 4 4 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFQ95386.1 - 6.6e-06 25.6 0.0 0.15 11.6 0.0 3.9 3 0 0 3 3 3 1 Immunoglobulin domain Ig_4 PF16680.5 KFQ95386.1 - 6.7e-06 26.3 0.0 0.37 11.1 0.0 5.0 4 1 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain DUF2369 PF10179.9 KFQ95386.1 - 5.6e-05 23.4 0.0 7.1 7.1 0.0 5.1 5 0 0 5 5 5 0 Uncharacterised conserved protein (DUF2369) Protocadherin PF08374.11 KFQ95386.1 - 0.00018 21.6 0.2 0.00035 20.6 0.2 1.4 1 0 0 1 1 1 1 Protocadherin CBM_4_9 PF02018.17 KFQ95386.1 - 0.00046 20.5 4.5 9.5 6.5 0.0 4.7 5 0 0 5 5 4 0 Carbohydrate binding domain EphA2_TM PF14575.6 KFQ95386.1 - 0.00061 20.6 0.0 0.0014 19.5 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SusE PF14292.6 KFQ95386.1 - 0.0033 17.6 0.1 1.9 8.8 0.0 3.8 3 0 0 3 3 3 1 SusE outer membrane protein V-set_CD47 PF08204.11 KFQ95386.1 - 0.021 14.8 0.0 0.36 10.8 0.0 2.7 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain FAM176 PF14851.6 KFQ95386.1 - 0.028 14.1 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 FAM176 family Izumo-Ig PF16706.5 KFQ95386.1 - 0.04 14.0 0.2 6.4 6.9 0.1 3.5 4 1 0 4 4 2 0 Izumo-like Immunoglobulin domain Arylsulfotran_N PF17425.2 KFQ95386.1 - 0.042 13.9 1.6 0.098 12.7 0.2 2.3 2 0 0 2 2 2 0 Arylsulfotransferase Ig-like domain Ig_C17orf99 PF17736.1 KFQ95386.1 - 0.043 13.9 0.0 28 4.8 0.0 3.8 4 0 0 4 4 3 0 C17orf99 Ig domain CD34_antigen PF06365.12 KFQ95386.1 - 0.047 13.3 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF4998 PF16389.5 KFQ95386.1 - 0.051 13.2 0.0 0.73 9.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function TMEM154 PF15102.6 KFQ95386.1 - 0.059 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 TMEM154 protein family Shisa PF13908.6 KFQ95386.1 - 0.36 11.1 5.6 1.6 9.0 5.3 2.2 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator KH_1 PF00013.29 KFQ95387.1 - 1.1e-21 76.4 0.8 3.6e-14 52.3 0.1 2.3 2 0 0 2 2 2 2 KH domain zf-C3HC4_3 PF13920.6 KFQ95387.1 - 9e-11 41.5 11.7 1.3e-10 40.9 11.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFQ95387.1 - 9.7e-07 28.6 10.9 1.6e-06 27.8 10.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFQ95387.1 - 0.00013 21.8 13.1 0.00021 21.1 13.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFQ95387.1 - 0.023 14.7 10.9 0.042 13.8 10.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFQ95387.1 - 0.068 13.2 7.4 0.043 13.9 5.0 2.0 1 1 1 2 2 2 0 RING-type zinc-finger zf-C2HC5 PF06221.13 KFQ95387.1 - 0.079 13.0 6.2 0.18 11.8 6.2 1.6 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type KH_2 PF07650.17 KFQ95387.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 KH domain zf-RING_4 PF14570.6 KFQ95387.1 - 1.5 8.6 9.1 3.1 7.7 9.1 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Lactamase_B PF00753.27 KFQ95388.1 - 1.7e-12 47.8 0.0 4e-12 46.6 0.0 1.5 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 KFQ95388.1 - 1.4e-06 27.9 0.0 3.2e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 KFQ95388.1 - 5.3e-06 26.1 0.0 7.6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Malic_M PF03949.15 KFQ95389.1 - 5.2e-98 327.4 0.4 6.7e-98 327.1 0.4 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KFQ95389.1 - 1.3e-79 266.3 0.0 2.5e-79 265.3 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Pol_alpha_B_N PF08418.10 KFQ95389.1 - 0.042 13.8 0.1 0.072 13.0 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Pkinase PF00069.25 KFQ95390.1 - 3.4e-74 249.5 0.0 4.3e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ95390.1 - 9.2e-31 107.1 0.0 1.2e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFQ95390.1 - 0.00027 20.4 0.1 0.00045 19.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SKA1 PF07160.12 KFQ95391.1 - 1.2e-81 274.1 9.7 1.4e-81 273.9 9.7 1.0 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 DUF3161 PF11362.8 KFQ95391.1 - 0.024 14.6 0.0 0.062 13.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) OmpH PF03938.14 KFQ95391.1 - 0.024 15.0 2.6 0.21 11.9 1.1 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF3427 PF11907.8 KFQ95391.1 - 0.061 12.6 2.9 0.19 11.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3427) Occludin_ELL PF07303.13 KFQ95391.1 - 0.51 11.1 7.4 3 8.6 0.2 3.1 3 1 0 3 3 3 0 Occludin homology domain DUF755 PF05501.11 KFQ95391.1 - 1.7 8.9 7.4 3.6 7.9 7.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Tetraspanin PF00335.20 KFQ95392.1 - 4.3e-34 118.2 3.4 4.8e-34 118.1 3.4 1.0 1 0 0 1 1 1 1 Tetraspanin family OPT PF03169.15 KFQ95392.1 - 0.0026 16.5 4.2 0.0034 16.1 4.2 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SUR7 PF06687.12 KFQ95392.1 - 0.0034 17.0 2.1 0.0047 16.6 2.1 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF2162 PF09930.9 KFQ95392.1 - 0.0089 15.5 2.3 0.011 15.2 2.3 1.1 1 0 0 1 1 1 1 Predicted transporter (DUF2162) Solute_trans_a PF03619.16 KFQ95392.1 - 0.025 14.1 1.0 0.031 13.8 1.0 1.2 1 0 0 1 1 1 0 Organic solute transporter Ostalpha FtsX PF02687.21 KFQ95392.1 - 0.032 14.7 6.1 0.9 10.1 0.4 2.2 1 1 1 2 2 2 0 FtsX-like permease family DUF2207 PF09972.9 KFQ95392.1 - 0.13 11.0 1.4 0.17 10.6 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Pilin_N PF07790.11 KFQ95392.1 - 0.2 12.6 0.0 0.2 12.6 0.0 2.2 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal DUF2371 PF10177.9 KFQ95392.1 - 0.49 10.6 0.1 0.49 10.6 0.1 1.7 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2371) DUF2976 PF11190.8 KFQ95392.1 - 0.56 10.0 3.7 0.2 11.5 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Chordopox_A13L PF05961.11 KFQ95392.1 - 3 8.1 8.0 25 5.2 0.0 2.3 2 0 0 2 2 2 0 Chordopoxvirus A13L protein TMEM132D_C PF15706.5 KFQ95392.1 - 4.3 7.2 6.1 13 5.6 6.1 1.9 1 1 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF2367 PF10164.9 KFQ95392.1 - 9.7 6.8 8.2 3.5 8.2 3.6 2.4 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2367) TPH PF13868.6 KFQ95393.1 - 4e-14 51.9 146.4 4e-14 51.9 146.4 2.2 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Myosin_head PF00063.21 KFQ95394.1 - 1.7e-282 938.7 9.7 1.9e-282 938.5 9.7 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 KFQ95394.1 - 1.4e-05 24.5 8.3 0.00041 19.9 1.9 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif Myosin_N PF02736.19 KFQ95394.1 - 0.00074 19.3 1.5 0.0013 18.5 0.4 2.0 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 KFQ95394.1 - 0.004 17.4 0.0 0.018 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFQ95394.1 - 0.025 15.0 0.0 0.066 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 KFQ95394.1 - 0.079 12.0 0.3 0.26 10.3 0.0 2.0 3 0 0 3 3 3 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KFQ95394.1 - 0.081 12.2 0.1 1 8.6 0.0 2.5 2 1 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.26 KFQ95394.1 - 0.11 12.2 0.1 0.52 10.0 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Csm1_N PF18504.1 KFQ95395.1 - 0.001 19.4 17.2 0.079 13.3 4.3 2.4 2 0 0 2 2 2 2 Csm1 N-terminal domain FapA PF03961.13 KFQ95395.1 - 0.0014 17.3 11.5 0.0016 17.2 11.5 1.0 1 0 0 1 1 1 1 Flagellar Assembly Protein A bZIP_1 PF00170.21 KFQ95395.1 - 0.0033 17.5 17.4 0.023 14.8 7.4 2.4 2 0 0 2 2 2 2 bZIP transcription factor DUF2508 PF10704.9 KFQ95395.1 - 0.013 15.7 3.0 0.013 15.7 3.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2508) DUF1825 PF08855.10 KFQ95395.1 - 0.065 13.2 6.9 0.053 13.4 5.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1825) Peptidase_C9 PF01707.16 KFQ95395.1 - 0.07 12.7 0.3 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 Peptidase family C9 IZUMO PF15005.6 KFQ95395.1 - 0.074 13.6 13.4 0.071 13.6 12.4 1.4 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated DUF2492 PF10678.9 KFQ95395.1 - 0.077 13.3 1.7 0.14 12.5 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2492) LMBR1 PF04791.16 KFQ95395.1 - 0.089 11.7 9.9 0.1 11.5 9.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.6 KFQ95395.1 - 0.11 11.9 9.5 0.13 11.6 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 KFQ95395.1 - 0.11 12.5 22.7 0.16 12.0 22.7 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ApoO PF09769.9 KFQ95395.1 - 0.13 12.2 4.1 0.48 10.4 0.4 2.1 2 0 0 2 2 2 0 Apolipoprotein O T6PP_N PF18572.1 KFQ95395.1 - 0.15 11.9 8.3 1.1 9.1 6.7 2.1 1 1 1 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Prefoldin_2 PF01920.20 KFQ95395.1 - 0.27 11.2 20.9 0.87 9.6 7.2 2.5 2 0 0 2 2 2 0 Prefoldin subunit DUF4795 PF16043.5 KFQ95395.1 - 0.37 10.4 16.3 0.46 10.1 15.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) TMF_TATA_bd PF12325.8 KFQ95395.1 - 0.42 10.8 21.5 0.91 9.8 8.0 2.4 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Prefoldin PF02996.17 KFQ95395.1 - 0.43 10.5 14.5 0.86 9.5 4.2 2.4 2 0 0 2 2 2 0 Prefoldin subunit Uso1_p115_C PF04871.13 KFQ95395.1 - 0.63 10.4 19.5 1 9.7 18.3 1.8 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region APG6_N PF17675.1 KFQ95395.1 - 0.72 10.4 29.3 0.35 11.4 14.6 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF2383 PF09537.10 KFQ95395.1 - 0.82 10.0 8.6 0.94 9.8 1.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF2383) LpqV PF17301.2 KFQ95395.1 - 0.87 9.9 2.8 24 5.2 0.1 2.1 2 0 0 2 2 2 0 Putative lipoprotein LpqV dCache_1 PF02743.18 KFQ95395.1 - 0.95 9.2 4.3 1.5 8.5 4.4 1.4 1 1 0 1 1 1 0 Cache domain betaPIX_CC PF16523.5 KFQ95395.1 - 1 9.3 15.1 0.65 9.9 4.9 2.5 2 0 0 2 2 2 0 betaPIX coiled coil OmpH PF03938.14 KFQ95395.1 - 1 9.7 29.0 3.3 8.1 22.3 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Ax_dynein_light PF10211.9 KFQ95395.1 - 1 9.3 20.9 3 7.8 9.7 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain V_ATPase_I PF01496.19 KFQ95395.1 - 1.1 7.0 12.6 1.4 6.8 12.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.6 KFQ95395.1 - 1.4 8.3 27.6 0.17 11.2 12.5 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.12 KFQ95395.1 - 1.5 9.4 9.7 3.3 8.2 2.2 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TPD52 PF04201.15 KFQ95395.1 - 1.5 8.4 11.3 1.2 8.7 9.7 1.7 1 1 0 1 1 1 0 Tumour protein D52 family Clr5 PF14420.6 KFQ95395.1 - 1.6 9.0 6.1 2.6 8.4 2.3 2.7 2 1 0 2 2 1 0 Clr5 domain Taxilin PF09728.9 KFQ95395.1 - 1.9 7.6 27.7 2.2 7.4 23.6 2.2 2 1 0 2 2 1 0 Myosin-like coiled-coil protein DUF724 PF05266.14 KFQ95395.1 - 2.3 8.0 16.3 4.3 7.1 5.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DHHA1 PF02272.19 KFQ95395.1 - 2.5 8.5 10.6 1.1 9.6 2.4 2.1 2 0 0 2 2 2 0 DHHA1 domain RasGAP_C PF03836.15 KFQ95395.1 - 2.7 8.1 15.5 3.3 7.9 5.9 2.4 1 1 1 2 2 2 0 RasGAP C-terminus zf-C4H2 PF10146.9 KFQ95395.1 - 3 8.1 11.3 3.7 7.8 11.3 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein FAM184 PF15665.5 KFQ95395.1 - 3.1 7.5 23.6 0.9 9.3 17.2 2.0 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B SlyX PF04102.12 KFQ95395.1 - 3.2 8.5 18.6 12 6.6 1.0 3.3 1 1 2 3 3 3 0 SlyX Seryl_tRNA_N PF02403.22 KFQ95395.1 - 3.2 8.0 16.6 60 3.9 16.6 2.3 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Phage_GP20 PF06810.11 KFQ95395.1 - 4 7.2 18.7 1.8 8.4 6.7 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 Exonuc_VII_L PF02601.15 KFQ95395.1 - 4.3 6.8 11.5 5.2 6.5 11.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sulfatase_C PF14707.6 KFQ95395.1 - 7.4 7.3 7.0 20 5.9 1.3 2.2 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase HU-CCDC81_bac_2 PF18175.1 KFQ95395.1 - 7.8 6.4 9.0 10 6.1 2.2 2.4 1 1 1 2 2 2 0 CCDC81-like prokaryotic HU domain 2 TEX13 PF15186.6 KFQ95395.1 - 8 6.1 16.9 3 7.5 7.1 2.3 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family ALMT PF11744.8 KFQ95395.1 - 8.1 5.2 8.0 8.9 5.0 8.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Thiolase_N PF00108.23 KFQ95396.1 - 2.3e-91 305.8 0.1 3.7e-91 305.1 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFQ95396.1 - 5.2e-53 177.9 0.3 1.2e-52 176.7 0.3 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFQ95396.1 - 4.7e-05 23.1 1.4 0.0017 18.0 0.7 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 KFQ95396.1 - 0.12 12.5 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Peptidase_C12 PF01088.21 KFQ95397.1 - 6.9e-60 202.4 0.0 7.8e-60 202.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 COMM_domain PF07258.14 KFQ95398.1 - 2.1e-17 63.0 0.0 3.5e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 COMM domain DUF3870 PF12986.7 KFQ95398.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) RabGAP-TBC PF00566.18 KFQ95400.1 - 1.8e-52 178.1 0.8 5.2e-52 176.6 0.8 1.9 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3350 PF11830.8 KFQ95400.1 - 2e-29 101.7 3.5 7e-29 99.9 3.5 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3350) PID PF00640.23 KFQ95400.1 - 8.7e-08 32.3 0.6 1.3e-06 28.5 0.5 2.5 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) Laminin_I PF06008.14 KFQ95400.1 - 0.0048 16.6 5.6 0.0048 16.6 5.6 2.0 2 0 0 2 2 2 1 Laminin Domain I RecR PF02132.15 KFQ95400.1 - 0.022 14.3 0.9 0.08 12.5 0.9 2.0 1 0 0 1 1 1 0 RecR protein PTB PF08416.13 KFQ95400.1 - 0.054 13.7 0.4 0.25 11.5 0.2 2.4 2 0 0 2 2 2 0 Phosphotyrosine-binding domain DUF4249 PF14054.6 KFQ95400.1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4249) TSP_NTD PF17804.1 KFQ95400.1 - 1.1 9.5 7.7 0.15 12.3 1.5 2.4 2 0 0 2 2 2 0 Tail specific protease N-terminal domain Uso1_p115_C PF04871.13 KFQ95400.1 - 2.2 8.7 12.7 0.18 12.2 5.1 2.8 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Plk4_PB2 PF18409.1 KFQ95400.1 - 6.8 7.4 8.3 4.3 8.1 0.1 3.8 3 0 0 3 3 3 0 Polo-like Kinase 4 Polo Box 2 Pkinase PF00069.25 KFQ95401.1 - 2.1e-75 253.5 0.0 2.6e-75 253.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ95401.1 - 2.9e-34 118.5 0.0 3.7e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFQ95401.1 - 7.7e-05 22.1 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFQ95401.1 - 0.00039 19.8 0.0 0.00087 18.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFQ95401.1 - 0.0016 17.3 0.4 0.004 16.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 KFQ95401.1 - 0.093 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 KFQ95401.1 - 0.12 11.9 0.2 0.25 10.9 0.2 1.4 1 0 0 1 1 1 0 RIO1 family DCX PF03607.17 KFQ95402.1 - 5.1e-37 125.8 0.1 5.5e-23 80.8 0.0 2.5 2 0 0 2 2 2 2 Doublecortin Cyclin_N PF00134.23 KFQ95403.1 - 2.9e-47 159.6 0.1 4.7e-47 158.9 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFQ95403.1 - 6e-29 100.5 2.2 8.6e-29 100.1 0.9 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N2 PF16500.5 KFQ95403.1 - 0.0043 17.8 0.0 0.0071 17.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of cyclin_N SRTM1 PF15872.5 KFQ95405.1 - 1e-52 176.6 11.0 1.1e-52 176.5 11.0 1.0 1 0 0 1 1 1 1 Serine-rich and transmembrane domain-containing protein 1 MH2 PF03166.14 KFQ95406.1 - 1.4e-74 250.3 1.6 1.9e-74 249.9 1.6 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 KFQ95406.1 - 1.5e-42 144.0 1.2 3.6e-42 142.8 1.2 1.7 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.9 KFQ95406.1 - 0.0013 18.5 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 DUF4223 PF13978.6 KFQ95406.1 - 0.02 14.8 0.5 0.044 13.8 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) Glycos_transf_2 PF00535.26 KFQ95407.1 - 2.9e-24 85.8 0.0 3.5e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KFQ95407.1 - 4.1e-08 33.4 0.0 6.4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KFQ95407.1 - 0.0027 17.2 0.0 0.0034 16.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Fasciclin PF02469.22 KFQ95408.1 - 3.1e-104 344.3 0.1 3.9e-27 95.0 0.4 4.4 4 0 0 4 4 4 4 Fasciclin domain Ion_trans PF00520.31 KFQ95411.1 - 3.1e-33 115.0 14.4 4.7e-33 114.4 14.4 1.2 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.11 KFQ95411.1 - 1.3e-28 99.0 0.8 2.8e-28 97.9 0.8 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.7 KFQ95411.1 - 6.2e-10 39.5 0.4 2.6e-05 24.7 0.4 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ95411.1 - 6.1e-09 36.2 0.0 0.00097 19.7 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ95411.1 - 2e-06 27.7 2.8 0.13 12.9 0.1 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KFQ95411.1 - 6.3e-05 23.2 0.1 1.1 9.6 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KFQ95411.1 - 0.00015 22.0 0.4 1 9.9 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat PKD_channel PF08016.12 KFQ95411.1 - 0.00046 19.0 15.7 0.005 15.6 15.7 2.3 1 1 0 1 1 1 1 Polycystin cation channel Gp-FAR-1 PF05823.12 KFQ95411.1 - 1.6 9.1 6.8 7.1 7.0 0.1 2.9 3 0 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) TED_complement PF07678.14 KFQ95413.1 - 2.8e-85 286.1 3.8 6.6e-85 284.9 3.8 1.6 1 1 0 1 1 1 1 A-macroglobulin TED domain A2M PF00207.22 KFQ95413.1 - 2.2e-29 101.1 0.2 9.8e-29 99.1 0.2 2.2 2 0 0 2 2 2 1 Alpha-2-macroglobulin family A2M_recep PF07677.14 KFQ95413.1 - 5.1e-26 91.2 5.9 6.3e-24 84.5 0.0 4.6 4 0 0 4 4 4 1 A-macroglobulin receptor binding domain A2M_BRD PF07703.14 KFQ95413.1 - 1.8e-25 89.9 0.3 3.8e-22 79.2 0.0 3.4 3 0 0 3 3 3 2 Alpha-2-macroglobulin bait region domain NTR PF01759.21 KFQ95413.1 - 2.3e-22 78.8 0.3 7.4e-22 77.2 0.3 2.0 1 0 0 1 1 1 1 UNC-6/NTR/C345C module MG1 PF17790.1 KFQ95413.1 - 3.9e-21 75.4 1.7 1.9e-20 73.2 1.7 2.3 1 0 0 1 1 1 1 Macroglobulin domain MG1 MG2 PF01835.19 KFQ95413.1 - 1.4e-16 60.7 0.1 1e-13 51.5 0.0 3.7 3 0 0 3 3 3 1 MG2 domain MG4 PF17789.1 KFQ95413.1 - 4.6e-14 52.3 0.0 2.5e-13 50.0 0.0 2.4 1 0 0 1 1 1 1 Macroglobulin domain MG4 MG3 PF17791.1 KFQ95413.1 - 6.7e-13 48.7 0.0 3.4e-12 46.5 0.0 2.3 2 0 0 2 2 2 1 Macroglobulin domain MG3 ANATO PF01821.18 KFQ95413.1 - 6.7e-11 42.9 7.5 1.8e-10 41.5 7.5 1.8 1 0 0 1 1 1 1 Anaphylotoxin-like domain DUF4476 PF14771.6 KFQ95414.1 - 1.2e-20 73.5 4.6 6.1e-17 61.7 1.3 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4476) NHL PF01436.21 KFQ95415.1 - 7.9e-12 44.6 3.0 4.1e-06 26.6 0.2 4.9 5 0 0 5 5 5 3 NHL repeat SGL PF08450.12 KFQ95415.1 - 0.00013 21.6 0.4 0.077 12.6 0.0 3.5 3 1 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Tachylectin PF14517.6 KFQ95415.1 - 0.0015 18.1 0.4 0.0033 17.0 0.4 1.6 1 0 0 1 1 1 1 Tachylectin DUF2025 PF09634.10 KFQ95415.1 - 0.024 14.6 0.0 0.072 13.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2025) Proteasome_A_N PF10584.9 KFQ95415.1 - 0.11 12.2 0.2 0.54 10.0 0.0 2.3 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature L_HMGIC_fpl PF10242.9 KFQ95416.1 - 2.5e-29 102.8 3.1 2.8e-29 102.6 3.1 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein UPF0016 PF01169.19 KFQ95416.1 - 0.24 11.8 4.7 0.075 13.4 1.4 1.8 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 COG6 PF06419.11 KFQ95417.1 - 2.9e-211 703.0 10.7 3.4e-211 702.8 10.7 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Sec34 PF04136.15 KFQ95417.1 - 0.0054 16.6 1.6 0.017 15.0 1.6 1.9 1 0 0 1 1 1 1 Sec34-like family YabA PF06156.13 KFQ95417.1 - 0.0065 17.1 1.2 0.03 14.9 1.2 2.2 1 0 0 1 1 1 1 Initiation control protein YabA SOGA PF11365.8 KFQ95417.1 - 0.03 15.5 3.9 0.033 15.3 1.5 2.4 2 0 0 2 2 2 0 Protein SOGA Jnk-SapK_ap_N PF09744.9 KFQ95417.1 - 0.032 14.5 3.0 0.11 12.7 3.0 2.0 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Takusan PF04822.13 KFQ95417.1 - 0.083 12.8 2.0 0.16 11.9 0.5 2.3 2 0 0 2 2 2 0 Takusan Mod_r PF07200.13 KFQ95417.1 - 0.32 11.1 9.5 13 5.8 4.7 2.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein BLOC1_2 PF10046.9 KFQ95417.1 - 0.49 10.7 5.8 0.2 12.0 2.1 2.4 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1043 PF06295.12 KFQ95417.1 - 0.67 10.0 3.8 0.7 9.9 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Nup54 PF13874.6 KFQ95417.1 - 0.73 9.9 4.3 0.68 10.0 1.4 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 GLTSCR1 PF15249.6 KFQ95417.1 - 0.82 10.2 4.0 0.75 10.3 1.5 2.1 1 1 1 2 2 2 0 Conserved region of unknown function on GLTSCR protein Syntaxin-6_N PF09177.11 KFQ95417.1 - 1.2 9.7 4.3 20 5.8 2.4 3.0 2 1 0 2 2 2 0 Syntaxin 6, N-terminal FOXO_KIX_bdg PF16675.5 KFQ95418.1 - 5.8e-30 103.4 1.9 5.8e-30 103.4 1.9 2.9 2 0 0 2 2 2 1 KIX-binding domain of forkhead box O, CR2 FOXO-TAD PF16676.5 KFQ95418.1 - 6.5e-21 74.5 8.6 1.4e-20 73.4 8.6 1.6 1 0 0 1 1 1 1 Transactivation domain of FOXO protein family Forkhead PF00250.18 KFQ95418.1 - 2.2e-08 34.2 0.2 4.9e-08 33.1 0.2 1.6 1 0 0 1 1 1 1 Forkhead domain MRP-S31 PF15433.6 KFQ95419.1 - 4.5e-71 240.1 7.3 4.9e-71 240.0 7.3 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 Mito_carr PF00153.27 KFQ95420.1 - 1.2e-58 195.0 5.9 2.5e-19 69.0 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fibrillarin PF01269.17 KFQ95420.1 - 0.17 11.0 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin PTEN_C2 PF10409.9 KFQ95421.1 - 5.4e-25 87.7 0.1 1.1e-24 86.7 0.1 1.6 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Ion_trans PF00520.31 KFQ95421.1 - 6.8e-13 48.4 7.3 1e-12 47.9 7.3 1.3 1 0 0 1 1 1 1 Ion transport protein DSPc PF00782.20 KFQ95421.1 - 3.4e-09 36.6 0.0 9.3e-09 35.2 0.0 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFQ95421.1 - 1.6e-05 25.1 0.0 2.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KFQ95421.1 - 9.4e-05 22.1 0.0 0.00018 21.2 0.0 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PKD_channel PF08016.12 KFQ95421.1 - 0.0046 15.7 4.2 0.0076 15.0 4.2 1.4 1 0 0 1 1 1 1 Polycystin cation channel Y_phosphatase3 PF13350.6 KFQ95421.1 - 0.034 14.1 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF4282 PF14110.6 KFQ95421.1 - 2.1 9.1 9.2 0.17 12.7 4.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4282) KASH PF10541.9 KFQ95422.1 - 0.043 14.1 0.6 0.063 13.6 0.6 1.3 1 0 0 1 1 1 0 Nuclear envelope localisation domain Fibrinogen_C PF00147.18 KFQ95423.1 - 5.7e-55 186.5 10.1 6.3e-55 186.4 10.1 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain TSP_1 PF00090.19 KFQ95424.1 - 3.7e-11 43.1 6.9 1.6e-10 41.0 6.9 2.2 1 0 0 1 1 1 1 Thrombospondin type 1 domain AJAP1_PANP_C PF15298.6 KFQ95424.1 - 0.015 15.6 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 AJAP1/PANP C-terminus EAP30 PF04157.16 KFQ95425.1 - 2.1e-42 145.0 1.0 3e-42 144.5 1.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 KFQ95425.1 - 3e-12 46.6 0.0 6e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 KFQ95425.1 - 0.0018 18.1 0.0 0.0057 16.5 0.0 1.8 2 0 0 2 2 2 1 GRAM domain DUF1351 PF07083.11 KFQ95425.1 - 0.017 14.9 1.7 0.027 14.2 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) PH_TFIIH PF08567.11 KFQ95425.1 - 0.026 14.8 0.0 0.053 13.8 0.0 1.5 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain TssO PF17561.2 KFQ95425.1 - 0.039 14.1 1.2 0.069 13.2 1.2 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssO BBL5 PF07289.11 KFQ95425.1 - 0.045 12.8 0.1 0.18 10.8 0.0 1.9 2 0 0 2 2 2 0 Bardet-Biedl syndrome 5 protein TTRAP PF14203.6 KFQ95425.1 - 0.16 12.0 4.6 0.21 11.6 1.9 2.2 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein SpmSyn_N PF17950.1 KFQ95425.1 - 0.23 11.7 0.8 4.1 7.6 0.0 2.7 2 1 1 3 3 3 0 S-adenosylmethionine decarboxylase N -terminal YtxH PF12732.7 KFQ95425.1 - 5.1 7.7 8.5 2.8 8.5 5.3 2.1 2 0 0 2 2 2 0 YtxH-like protein CKAP2_C PF15297.6 KFQ95426.1 - 1.8e-77 260.8 30.6 9e-51 173.0 6.0 3.2 2 2 2 4 4 4 2 Cytoskeleton-associated protein 2 C-terminus Pkinase PF00069.25 KFQ95427.1 - 3e-67 226.8 0.3 4.8e-67 226.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ95427.1 - 4e-46 157.4 0.0 6.3e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ95427.1 - 7.2e-08 32.1 0.1 3.9e-07 29.7 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KFQ95427.1 - 0.0041 17.1 0.0 2.1 8.2 0.0 2.3 1 1 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFQ95427.1 - 0.04 12.7 0.1 0.13 11.0 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 KFQ95427.1 - 0.067 12.5 0.3 0.13 11.6 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ku_PK_bind PF08785.11 KFQ95427.1 - 0.12 12.5 0.2 0.35 11.0 0.0 1.8 2 0 0 2 2 2 0 Ku C terminal domain like Pkinase PF00069.25 KFQ95428.1 - 3.3e-66 223.3 0.2 5.1e-66 222.7 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ95428.1 - 4e-46 157.4 0.1 6.2e-46 156.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ95428.1 - 2.4e-06 27.1 0.2 0.00014 21.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KFQ95428.1 - 4.2e-05 22.5 0.0 8.7e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase ALG11_N PF15924.5 KFQ95429.1 - 1.8e-92 309.1 0.1 2.4e-92 308.7 0.1 1.1 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KFQ95429.1 - 1.2e-29 103.0 0.0 2e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFQ95429.1 - 6.8e-14 52.4 0.0 1.3e-13 51.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KFQ95429.1 - 6.6e-05 23.2 0.0 0.00012 22.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFQ95429.1 - 0.0056 16.7 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 DUF4389 PF14333.6 KFQ95429.1 - 0.76 9.7 2.9 0.6 10.1 0.2 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4389) HMA PF00403.26 KFQ95430.1 - 9.4e-71 234.2 0.2 4.2e-14 52.7 0.0 6.8 6 0 0 6 6 6 6 Heavy-metal-associated domain Hydrolase PF00702.26 KFQ95430.1 - 6.1e-62 209.6 1.1 1.1e-61 208.8 1.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFQ95430.1 - 6.1e-46 156.2 4.6 6.1e-46 156.2 4.6 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFQ95430.1 - 2.4e-07 30.8 2.4 4.4e-05 23.3 0.3 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KFQ95430.1 - 0.00016 21.7 0.7 0.006 16.7 0.1 3.1 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFQ95430.1 - 0.0061 16.7 0.1 0.016 15.3 0.1 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 KFQ95430.1 - 0.01 16.2 0.1 0.024 15.1 0.1 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SapB_2 PF03489.17 KFQ95430.1 - 0.021 14.9 0.3 0.072 13.2 0.3 2.0 1 0 0 1 1 1 0 Saposin-like type B, region 2 RRM_3 PF08777.11 KFQ95430.1 - 0.12 12.5 0.0 6 7.0 0.0 3.6 4 0 0 4 4 4 0 RNA binding motif DUF2200 PF09966.9 KFQ95430.1 - 0.71 10.0 3.7 17 5.6 0.0 3.9 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2200) GFA PF04828.14 KFQ95430.1 - 5.7 7.3 8.9 17 5.8 0.1 4.4 5 0 0 5 5 5 0 Glutathione-dependent formaldehyde-activating enzyme adh_short PF00106.25 KFQ95431.1 - 1.2e-27 96.7 0.3 1.8e-26 92.8 0.3 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFQ95431.1 - 3.1e-19 69.5 0.1 4.7e-18 65.6 0.1 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFQ95431.1 - 1.1e-10 41.8 0.1 1.7e-10 41.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFQ95431.1 - 2.2e-07 30.6 0.0 2.7e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KFQ95431.1 - 0.00025 20.5 0.1 0.016 14.6 0.0 2.5 2 1 0 2 2 2 1 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 KFQ95431.1 - 0.00071 19.1 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KFQ95431.1 - 0.0013 18.7 1.7 0.0049 16.8 0.8 2.4 1 1 0 2 2 2 1 NAD(P)H-binding WD40 PF00400.32 KFQ95432.1 - 5.6e-21 74.5 13.6 3.9e-07 30.7 1.3 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat FYVE PF01363.21 KFQ95432.1 - 2.4e-14 53.2 7.8 5.4e-14 52.1 7.8 1.6 1 0 0 1 1 1 1 FYVE zinc finger ANAPC4_WD40 PF12894.7 KFQ95432.1 - 2.7e-06 27.6 0.1 0.19 12.0 0.0 3.8 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KFQ95432.1 - 3.8e-05 22.6 0.6 0.39 9.4 0.0 3.4 3 2 1 4 4 4 2 Nup133 N terminal like FYVE_2 PF02318.16 KFQ95432.1 - 0.044 14.0 4.3 0.1 12.8 4.3 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger DZR PF12773.7 KFQ95432.1 - 0.087 12.9 7.2 0.69 10.0 7.2 2.5 1 1 0 1 1 1 0 Double zinc ribbon DUF2688 PF10892.8 KFQ95432.1 - 0.22 11.0 5.0 0.73 9.3 5.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2688) DiS_P_DiS PF06750.13 KFQ95432.1 - 7.1 6.8 7.3 51 4.1 6.6 2.7 2 1 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain INT_SG_DDX_CT_C PF15300.6 KFQ95433.1 - 5.5e-26 90.2 4.3 1.3e-25 89.0 4.3 1.7 1 0 0 1 1 1 1 INTS6/SAGE1/DDX26B/CT45 C-terminus VWA_2 PF13519.6 KFQ95433.1 - 9.2e-06 26.3 0.0 2.4e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain FAM124 PF15067.6 KFQ95434.1 - 1.6e-108 361.8 0.0 2.3e-108 361.2 0.0 1.2 1 0 0 1 1 1 1 FAM124 family RNase_H2-Ydr279 PF09468.10 KFQ95436.1 - 1.1e-16 61.4 1.0 2e-16 60.6 1.0 1.4 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KFQ95436.1 - 3.1e-13 49.8 0.0 5.7e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain L_lactis_RepB_C PF06430.12 KFQ95436.1 - 0.014 15.4 1.5 1.3 9.1 0.9 2.3 2 0 0 2 2 2 0 Lactococcus lactis RepB C-terminus DUF3892 PF13031.6 KFQ95436.1 - 0.062 13.9 0.8 0.11 13.2 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3892) Clc-like PF07062.12 KFQ95436.1 - 0.31 10.5 0.8 1 8.8 0.1 2.0 2 0 0 2 2 2 0 Clc-like DLEU7 PF15760.5 KFQ95437.1 - 5.8e-72 241.3 2.3 6.8e-72 241.1 2.3 1.0 1 0 0 1 1 1 1 Leukemia-associated protein 7 BTB_2 PF02214.22 KFQ95441.1 - 3.3e-19 69.0 0.1 8.5e-19 67.7 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KFQ95441.1 - 0.0031 17.6 0.0 0.0072 16.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain SPRY PF00622.28 KFQ95442.1 - 6.9e-17 61.7 0.0 8.8e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 SPRY domain Arm PF00514.23 KFQ95443.1 - 6.4e-88 286.4 17.1 1.2e-12 47.3 0.3 9.3 9 1 1 10 10 10 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 KFQ95443.1 - 3.7e-24 84.0 2.4 9.6e-23 79.5 3.3 2.4 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 KFQ95443.1 - 3.8e-24 84.7 1.3 1.4e-08 35.1 0.2 6.3 5 1 1 6 6 6 5 HEAT-like repeat HEAT_2 PF13646.6 KFQ95443.1 - 7.6e-18 64.7 0.3 9.8e-07 29.1 0.0 6.3 3 2 4 8 8 8 3 HEAT repeats HEAT PF02985.22 KFQ95443.1 - 1e-17 62.7 6.5 0.0032 17.6 0.0 6.8 7 0 0 7 7 6 3 HEAT repeat Adaptin_N PF01602.20 KFQ95443.1 - 8.3e-09 34.5 0.1 1.5e-08 33.7 0.1 1.3 1 1 0 1 1 1 1 Adaptin N terminal region IBB PF01749.20 KFQ95443.1 - 1.3e-07 32.0 0.8 3.2e-07 30.7 0.8 1.8 1 0 0 1 1 1 1 Importin beta binding domain Atx10homo_assoc PF09759.9 KFQ95443.1 - 1.2e-05 25.3 1.9 1.8 8.7 0.0 4.8 3 1 3 6 6 6 2 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 KFQ95443.1 - 1.2e-05 25.0 0.4 6.1 6.2 0.0 4.3 2 1 2 4 4 4 1 Armadillo-like V-ATPase_H_C PF11698.8 KFQ95443.1 - 1.6e-05 25.0 0.6 1.3 9.2 0.1 4.3 4 1 1 5 5 5 1 V-ATPase subunit H Cnd1 PF12717.7 KFQ95443.1 - 2.8e-05 24.2 0.4 0.29 11.2 0.0 3.4 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.14 KFQ95443.1 - 7.1e-05 22.3 0.4 0.011 15.0 0.1 2.5 1 1 1 2 2 2 1 V-ATPase subunit H RasGEF_N_2 PF14663.6 KFQ95443.1 - 0.019 15.4 0.1 14 6.2 0.0 3.8 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Mo25 PF08569.11 KFQ95443.1 - 0.022 14.2 0.1 0.042 13.2 0.1 1.6 1 0 0 1 1 1 0 Mo25-like DRIM PF07539.12 KFQ95443.1 - 0.1 10.9 0.1 5.6 5.1 0.0 2.4 2 0 0 2 2 2 0 Down-regulated in metastasis Proteasom_PSMB PF10508.9 KFQ95443.1 - 0.13 10.7 0.5 0.83 8.1 0.1 2.4 2 2 0 2 2 2 0 Proteasome non-ATPase 26S subunit RPEL PF02755.15 KFQ95443.1 - 0.14 11.9 0.2 23 4.9 0.1 2.7 2 0 0 2 2 2 0 RPEL repeat DUF1981 PF09324.10 KFQ95443.1 - 0.17 11.8 0.5 2.5 8.0 0.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1981) DCB PF16213.5 KFQ95443.1 - 0.21 11.2 0.8 1.2 8.8 0.0 2.4 3 0 0 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 CTNNBL PF08216.11 KFQ95443.1 - 0.21 11.8 2.0 33 4.7 0.0 3.8 4 2 1 5 5 4 0 Catenin-beta-like, Arm-motif containing nuclear Arf PF00025.21 KFQ95444.1 - 4.6e-51 172.7 0.0 5.2e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFQ95444.1 - 9.7e-11 41.9 0.0 1.2e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KFQ95444.1 - 1.5e-10 40.8 0.0 1.5e-07 30.9 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KFQ95444.1 - 1.2e-09 38.0 0.0 1.5e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFQ95444.1 - 1.1e-08 34.7 0.0 1.4e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFQ95444.1 - 0.00031 20.2 0.0 0.00042 19.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFQ95444.1 - 0.00091 19.3 0.0 0.0013 18.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RCC1 PF00415.18 KFQ95445.1 - 1.9e-62 207.7 25.8 7e-15 55.4 2.0 6.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFQ95445.1 - 9.3e-34 114.5 32.3 5.5e-10 38.8 2.3 6.6 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KFQ95445.1 - 2.3e-22 79.3 0.6 2e-20 73.1 0.1 2.3 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFQ95445.1 - 1.3e-06 28.4 1.1 0.007 16.5 0.1 3.3 2 1 1 3 3 3 2 BTB And C-terminal Kelch PQQ_3 PF13570.6 KFQ95445.1 - 0.72 10.4 4.4 19 5.9 0.0 3.9 4 0 0 4 4 4 0 PQQ-like domain zf-HC5HC2H PF13771.6 KFQ95446.1 - 1.1e-14 54.4 1.6 1.1e-14 54.4 1.6 2.1 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFQ95446.1 - 1.3e-07 31.8 6.5 1e-06 28.9 6.4 2.1 1 1 0 1 1 1 1 PHD-zinc-finger like domain PHD PF00628.29 KFQ95446.1 - 0.00031 20.6 4.8 0.012 15.5 2.4 2.5 2 0 0 2 2 2 2 PHD-finger CEBP_ZZ PF16366.5 KFQ95446.1 - 1.7 8.9 9.1 0.18 12.1 4.2 1.9 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain SET PF00856.28 KFQ95447.1 - 8.7e-27 94.6 0.6 6.6e-26 91.7 0.1 2.4 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 KFQ95447.1 - 4.1e-15 56.4 6.4 4.1e-15 56.4 6.4 3.5 3 1 0 3 3 3 1 Pre-SET motif MBD PF01429.19 KFQ95447.1 - 8.7e-09 35.0 0.0 2.2e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Methyl-CpG binding domain Mo25 PF08569.11 KFQ95448.1 - 2.1e-132 441.4 11.5 2.4e-132 441.3 11.5 1.0 1 0 0 1 1 1 1 Mo25-like HEAT_2 PF13646.6 KFQ95448.1 - 0.047 14.1 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 HEAT repeats WcbI PF18588.1 KFQ95448.1 - 0.095 12.3 0.1 2.3 7.8 0.0 2.5 2 1 1 3 3 3 0 Polysaccharide biosynthesis enzyme WcbI JmjN PF02375.17 KFQ95448.1 - 0.49 10.4 2.3 3.1 7.8 0.2 3.0 3 0 0 3 3 3 0 jmjN domain dCMP_cyt_deam_1 PF00383.23 KFQ95449.1 - 5.5e-19 67.9 0.3 4.3e-09 36.2 0.0 2.7 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFQ95449.1 - 1.9e-12 47.1 0.3 3e-05 23.8 0.1 2.7 2 1 0 2 2 2 2 MafB19-like deaminase SNAD4 PF18750.1 KFQ95449.1 - 0.0063 16.6 0.6 0.94 9.6 0.1 2.6 2 0 0 2 2 2 2 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 KFQ95449.1 - 0.011 15.9 0.7 0.88 9.6 0.1 2.4 2 0 0 2 2 2 0 Novel AID APOBEC clade 1 APOBEC3 PF18771.1 KFQ95449.1 - 0.096 12.8 0.6 10 6.2 0.1 2.6 2 0 0 2 2 2 0 APOBEC3 AID PF18767.1 KFQ95449.1 - 0.14 12.2 0.1 20 5.3 0.0 2.7 2 0 0 2 2 2 0 Activation induced deaminase fn3 PF00041.21 KFQ95450.1 - 7.4e-87 285.8 0.0 9e-11 42.0 0.0 9.8 9 1 0 9 9 9 9 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFQ95450.1 - 8.1e-18 64.8 9.7 0.047 14.3 0.1 9.2 8 2 1 9 9 9 6 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 KFQ95450.1 - 1.1e-11 44.9 0.0 0.2 12.0 0.0 6.8 7 0 0 7 7 7 3 Uncharacterised conserved protein (DUF2369) Interfer-bind PF09294.10 KFQ95450.1 - 5.8e-06 26.6 4.6 0.064 13.6 0.1 5.4 6 0 0 6 6 6 2 Interferon-alpha/beta receptor, fibronectin type III IL6Ra-bind PF09240.10 KFQ95450.1 - 0.51 10.8 3.9 20 5.7 0.3 2.8 2 0 0 2 2 2 0 Interleukin-6 receptor alpha chain, binding 7tm_1 PF00001.21 KFQ95452.1 - 3.1e-48 164.4 25.9 3.1e-48 164.4 25.9 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFQ95452.1 - 2.3e-07 30.5 15.4 2.3e-07 30.5 15.4 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 KFQ95452.1 - 7.9e-07 29.0 20.9 7.9e-07 29.0 20.9 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 KFQ95452.1 - 0.00031 20.1 27.3 0.023 14.0 27.3 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw TAS2R PF05296.13 KFQ95452.1 - 0.032 13.3 26.4 0.087 11.9 26.4 1.6 1 1 0 1 1 1 0 Taste receptor protein (TAS2R) Saf_2TM PF18303.1 KFQ95452.1 - 0.054 13.1 0.6 0.99 9.0 0.0 2.6 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain DUF898 PF05987.13 KFQ95452.1 - 4.5 6.2 13.5 0.15 11.0 0.7 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF898) RCC1 PF00415.18 KFQ95453.1 - 5.4e-62 206.2 24.2 1.9e-15 57.2 1.6 6.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFQ95453.1 - 5.2e-32 109.0 25.3 2.9e-11 42.9 1.2 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KFQ95453.1 - 3.2e-20 72.4 1.1 2.4e-17 63.2 0.1 2.3 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.15 KFQ95453.1 - 3.1e-06 27.2 2.2 0.00034 20.7 0.3 3.1 2 1 1 3 3 3 1 BTB And C-terminal Kelch DUF4213 PF13938.6 KFQ95453.1 - 0.018 15.3 3.3 4.7 7.5 0.0 3.1 2 1 0 2 2 2 0 Putative heavy-metal chelation Phage_int_SAM_5 PF13102.6 KFQ95453.1 - 0.052 13.9 1.0 0.3 11.4 0.1 2.2 1 1 1 2 2 2 0 Phage integrase SAM-like domain Hira PF07569.11 KFQ95453.1 - 0.053 13.2 3.2 4.6 6.9 0.0 4.1 5 0 0 5 5 5 0 TUP1-like enhancer of split Kelch_5 PF13854.6 KFQ95453.1 - 3 7.9 8.6 45 4.2 0.2 4.4 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.15 KFQ95453.1 - 5.3 7.2 8.4 15 5.7 0.2 4.6 5 0 0 5 5 5 0 Kelch motif Rb_C PF08934.10 KFQ95454.1 - 2.8e-82 273.9 3.3 2.8e-82 273.9 3.3 2.5 3 0 0 3 3 3 1 Rb C-terminal domain RB_A PF01858.17 KFQ95454.1 - 8.6e-77 257.4 0.6 6.7e-76 254.5 0.1 2.5 2 0 0 2 2 2 1 Retinoblastoma-associated protein A domain RB_B PF01857.20 KFQ95454.1 - 1e-31 109.7 5.2 1e-31 109.7 5.2 2.3 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 KFQ95454.1 - 5.4e-14 51.9 2.8 5.4e-14 51.9 2.8 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3452) DUF1955 PF09205.10 KFQ95454.1 - 0.16 11.7 2.5 0.12 12.1 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1955) 7tm_1 PF00001.21 KFQ95455.1 - 1.5e-54 185.1 30.4 1.8e-54 184.8 30.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFQ95455.1 - 4.2e-05 23.3 30.9 4.2e-05 23.3 30.9 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx MscS_TM PF12794.7 KFQ95455.1 - 0.12 11.2 6.1 1.1 8.0 0.3 2.4 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 UCMA PF17085.5 KFQ95455.1 - 0.28 11.2 0.7 2.5 8.1 0.2 2.2 1 1 1 2 2 2 0 Unique cartilage matrix associated protein BRICHOS PF04089.14 KFQ95456.1 - 3.7e-20 72.0 0.0 5.7e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 BRICHOS domain Antiterm PF03589.13 KFQ95456.1 - 0.055 13.8 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 Antitermination protein Med4 PF10018.9 KFQ95457.1 - 2.2e-31 109.0 0.2 3.3e-31 108.5 0.2 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 HMMR_N PF15905.5 KFQ95457.1 - 0.00011 21.8 6.5 0.00015 21.3 6.5 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Mu-like_Pro PF10123.9 KFQ95457.1 - 0.0074 15.9 0.9 0.01 15.4 0.9 1.1 1 0 0 1 1 1 1 Mu-like prophage I protein Csm1_N PF18504.1 KFQ95457.1 - 0.06 13.7 5.9 0.16 12.4 5.9 1.8 1 1 0 1 1 1 0 Csm1 N-terminal domain Trans_reg_C PF00486.28 KFQ95457.1 - 0.2 11.8 1.3 3.6 7.7 0.3 2.5 1 1 1 2 2 2 0 Transcriptional regulatory protein, C terminal FAM76 PF16046.5 KFQ95457.1 - 0.29 10.5 4.0 0.39 10.0 4.0 1.1 1 0 0 1 1 1 0 FAM76 protein DUF724 PF05266.14 KFQ95457.1 - 0.29 11.0 5.4 0.42 10.4 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ATP-grasp_2 PF08442.10 KFQ95459.1 - 3.2e-74 248.9 1.1 7.1e-74 247.7 0.1 1.9 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KFQ95459.1 - 1.2e-26 93.3 2.6 2.1e-26 92.6 2.6 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KFQ95459.1 - 1.5e-09 37.7 0.4 3.9e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 KFQ95459.1 - 0.042 13.6 0.4 0.14 12.0 0.4 1.8 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain nsp7 PF08716.10 KFQ95459.1 - 0.079 13.6 1.9 1.6 9.4 0.3 2.7 2 1 0 2 2 2 0 nsp7 replicase 7tm_1 PF00001.21 KFQ95461.1 - 3.6e-67 226.5 15.2 5.2e-67 225.9 15.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ95461.1 - 1.7e-15 57.1 19.2 2.6e-15 56.5 19.2 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFQ95461.1 - 3.2e-07 30.4 10.0 3.2e-07 30.4 10.0 2.0 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFQ95461.1 - 4.6e-06 26.4 16.2 4.6e-06 26.4 16.2 2.5 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Bee_toxin PF17454.2 KFQ95461.1 - 3.9 7.6 10.5 0.062 13.3 1.3 2.6 2 0 0 2 2 2 0 Honey bee toxin Esterase PF00756.20 KFQ95462.1 - 2.6e-66 223.9 0.0 2.9e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 KFQ95462.1 - 7.6e-08 31.6 0.0 1.2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase_phd PF10503.9 KFQ95462.1 - 4.6e-05 23.0 0.0 0.0035 16.9 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KFQ95462.1 - 5.4e-05 22.8 0.0 8.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KFQ95462.1 - 6.5e-05 22.3 0.0 0.00012 21.5 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KFQ95462.1 - 9.1e-05 21.6 0.0 0.0011 18.1 0.0 2.1 1 1 0 1 1 1 1 Chlorophyllase AXE1 PF05448.12 KFQ95462.1 - 0.0032 16.2 0.0 0.0044 15.7 0.0 1.1 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 KFQ95462.1 - 0.064 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 KFQ95462.1 - 0.07 12.7 0.0 0.72 9.4 0.0 2.0 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KFQ95462.1 - 0.075 13.6 0.0 0.086 13.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 KFQ95462.1 - 0.079 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) LRR_8 PF13855.6 KFQ95463.1 - 1.7e-23 82.1 10.7 2.4e-10 40.0 1.4 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFQ95463.1 - 1.4e-15 57.1 16.2 0.00099 19.5 0.2 5.5 2 1 2 5 5 5 5 Leucine Rich repeats (2 copies) CH PF00307.31 KFQ95463.1 - 3.7e-11 43.2 0.0 9.1e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain LRR_1 PF00560.33 KFQ95463.1 - 4.5e-06 26.5 15.9 1.4 9.7 0.5 6.8 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.6 KFQ95463.1 - 0.0019 18.1 11.4 1.5 9.1 0.5 5.2 5 0 0 5 5 5 2 Leucine Rich repeat CAMSAP_CH PF11971.8 KFQ95463.1 - 0.0044 16.8 0.0 0.015 15.1 0.0 1.9 1 0 0 1 1 1 1 CAMSAP CH domain zf-RING_9 PF13901.6 KFQ95464.1 - 1.1e-66 224.8 21.2 1.7e-66 224.1 21.2 1.3 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon Ploopntkinase1 PF18748.1 KFQ95464.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 CH PF00307.31 KFQ95465.1 - 4.3e-76 252.1 2.2 1.1e-21 77.1 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 KFQ95465.1 - 1.7e-09 38.0 0.0 5.9e-09 36.3 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFQ95465.1 - 2.6e-08 32.8 0.2 0.0031 16.9 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFQ95465.1 - 1e-07 31.3 0.6 0.0015 18.3 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KFQ95465.1 - 0.00051 19.8 0.0 0.011 15.5 0.0 2.9 1 1 1 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.8 KFQ95465.1 - 0.00085 19.1 0.0 0.0049 16.7 0.0 2.3 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_5 PF13202.6 KFQ95465.1 - 0.0022 17.4 0.6 0.31 10.6 0.1 3.0 3 0 0 3 3 3 1 EF hand Peptidase_M14 PF00246.24 KFQ95466.1 - 1.8e-92 310.2 0.1 2.2e-92 310.0 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KFQ95466.1 - 1.5e-07 31.7 0.4 4.4e-07 30.2 0.4 1.8 1 0 0 1 1 1 1 Carboxypeptidase activation peptide tRNA-synt_1b PF00579.25 KFQ95466.1 - 2.7 7.2 5.5 1.5 8.0 0.5 2.6 2 1 1 3 3 3 0 tRNA synthetases class I (W and Y) Chibby PF14645.6 KFQ95467.1 - 0.022 15.1 0.5 0.022 15.1 0.5 2.9 3 0 0 3 3 3 0 Chibby family DUF3966 PF13110.6 KFQ95467.1 - 0.15 12.0 1.0 0.48 10.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3966) Mrpl_C PF18502.1 KFQ95468.1 - 0.02 15.2 0.3 0.023 14.9 0.3 1.1 1 0 0 1 1 1 0 54S ribosomal protein L8 C-terminal domain MAP70 PF07058.11 KFQ95468.1 - 0.11 11.3 3.3 0.1 11.3 3.3 1.0 1 0 0 1 1 1 0 Microtubule-associated protein 70 FAM194 PF14977.6 KFQ95469.1 - 1.4e-55 187.8 0.0 1.5e-55 187.7 0.0 1.0 1 0 0 1 1 1 1 FAM194 protein MORN_2 PF07661.13 KFQ95469.1 - 0.0081 16.3 0.0 0.47 10.8 0.0 2.8 2 0 0 2 2 2 1 MORN repeat variant MORN PF02493.20 KFQ95469.1 - 0.79 9.7 2.5 20 5.3 0.5 2.5 2 0 0 2 2 2 0 MORN repeat Sec34 PF04136.15 KFQ95470.1 - 2.7e-55 186.4 17.1 3.7e-55 185.9 6.7 4.0 4 0 0 4 4 4 2 Sec34-like family PP2C_C PF07830.13 KFQ95470.1 - 0.034 14.6 0.4 0.56 10.7 0.1 2.9 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain CLTH PF10607.9 KFQ95470.1 - 0.078 12.9 8.6 0.027 14.4 1.0 3.1 3 0 0 3 3 3 0 CTLH/CRA C-terminal to LisH motif domain Lant_dehydr_C PF14028.6 KFQ95470.1 - 0.13 11.8 0.1 2.4 7.6 0.0 2.6 2 0 0 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term NPV_P10 PF05531.12 KFQ95470.1 - 0.24 11.9 3.9 5.8 7.5 0.2 4.1 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 KFQ95470.1 - 6.2 6.9 15.8 4.6 7.3 4.1 4.8 5 1 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mito_carr PF00153.27 KFQ95471.1 - 2e-43 146.2 0.3 1.8e-19 69.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SpoVAB PF13782.6 KFQ95471.1 - 0.28 11.5 1.8 21 5.5 0.0 2.7 1 1 1 2 2 2 0 Stage V sporulation protein AB TCTP PF00838.17 KFQ95472.1 - 3.5e-59 199.9 0.2 3.9e-59 199.7 0.2 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Endotoxin_N PF03945.14 KFQ95472.1 - 0.011 15.5 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain TFIIF_beta PF02270.15 KFQ95473.1 - 8.5e-28 96.3 1.0 1.2e-27 95.8 0.2 1.7 2 0 0 2 2 2 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 KFQ95473.1 - 3.4e-14 53.7 0.6 1.9e-13 51.2 0.6 2.3 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus BTB_2 PF02214.22 KFQ95474.1 - 2.2e-18 66.4 0.1 6.2e-18 64.9 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 KFQ95474.1 - 0.0071 16.4 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF3752 PF12572.8 KFQ95475.1 - 2.4e-25 89.8 18.7 2.4e-25 89.8 18.7 1.8 1 1 0 2 2 2 1 Protein of unknown function (DUF3752) DUF5539 PF17693.1 KFQ95475.1 - 0.045 13.4 4.4 0.073 12.7 4.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5539) DUF4065 PF13274.6 KFQ95475.1 - 2.3 9.1 6.0 15 6.5 2.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4065) DUF4462 PF14692.6 KFQ95476.1 - 0.083 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) NUFIP1 PF10453.9 KFQ95477.1 - 5e-20 71.1 7.3 1.4e-19 69.7 7.3 1.9 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-C2H2_jaz PF12171.8 KFQ95477.1 - 2.6e-05 24.4 4.7 9.7e-05 22.5 3.9 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding PCNP PF15473.6 KFQ95477.1 - 0.0042 17.8 2.6 0.0042 17.8 2.6 2.2 3 0 0 3 3 3 1 PEST, proteolytic signal-containing nuclear protein family zf-C2H2 PF00096.26 KFQ95477.1 - 0.045 14.2 1.7 0.21 12.1 1.7 2.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ95477.1 - 0.41 11.6 4.0 2.2 9.3 0.2 2.9 1 1 1 2 2 2 0 C2H2-type zinc finger TSC22 PF01166.18 KFQ95479.1 - 1.5e-29 102.1 4.4 1.7e-29 101.9 4.4 1.1 1 0 0 1 1 1 1 TSC-22/dip/bun family YabA PF06156.13 KFQ95479.1 - 0.00019 22.0 3.2 0.00022 21.8 3.2 1.1 1 0 0 1 1 1 1 Initiation control protein YabA K-box PF01486.17 KFQ95479.1 - 0.0005 20.2 1.6 0.00061 19.9 1.6 1.1 1 0 0 1 1 1 1 K-box region DivIC PF04977.15 KFQ95479.1 - 0.0028 17.4 4.4 0.0033 17.2 4.1 1.3 1 1 0 1 1 1 1 Septum formation initiator ZapB PF06005.12 KFQ95479.1 - 0.02 15.3 8.0 0.028 14.8 8.0 1.5 1 1 0 1 1 1 0 Cell division protein ZapB Fzo_mitofusin PF04799.13 KFQ95479.1 - 0.024 14.2 1.8 0.026 14.1 1.8 1.0 1 0 0 1 1 1 0 fzo-like conserved region bZIP_2 PF07716.15 KFQ95479.1 - 0.042 13.9 5.2 0.072 13.2 5.2 1.3 1 0 0 1 1 1 0 Basic region leucine zipper NYD-SP28_assoc PF14775.6 KFQ95479.1 - 0.053 13.6 1.4 0.084 13.0 1.4 1.3 1 0 0 1 1 1 0 Sperm tail C-terminal domain bZIP_1 PF00170.21 KFQ95479.1 - 0.27 11.4 4.9 0.34 11.0 4.6 1.4 1 1 0 1 1 1 0 bZIP transcription factor Cu-oxidase_4 PF02578.15 KFQ95480.1 - 1.7e-56 191.4 0.0 2.2e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase bZIP_1 PF00170.21 KFQ95481.1 - 0.1 12.7 0.7 0.1 12.7 0.7 6.5 4 3 4 8 8 8 0 bZIP transcription factor TPR_MLP1_2 PF07926.12 KFQ95481.1 - 0.11 12.6 35.8 0.18 11.8 16.1 3.6 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KFQ95481.1 - 0.23 10.3 37.5 1 8.1 15.8 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KFQ95481.1 - 0.41 10.7 40.4 0.22 11.6 13.9 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_I PF06008.14 KFQ95481.1 - 0.63 9.7 28.6 0.16 11.7 18.8 2.7 1 1 2 3 3 3 0 Laminin Domain I DUF1664 PF07889.12 KFQ95481.1 - 0.99 9.4 24.3 1.2 9.2 4.4 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KFQ95481.1 - 1.2 9.2 6.8 1.4 9.0 0.8 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Hemagglutinin PF00509.18 KFQ95481.1 - 1.4 7.3 9.3 0.033 12.6 1.0 1.9 2 0 0 2 2 2 0 Haemagglutinin ENT PF03735.14 KFQ95481.1 - 1.4 9.0 9.2 2.4 8.3 5.3 3.0 2 1 0 2 2 2 0 ENT domain LPP PF04728.13 KFQ95481.1 - 1.5 9.3 7.4 13 6.3 0.0 4.7 4 2 1 5 5 5 0 Lipoprotein leucine-zipper MAD PF05557.13 KFQ95481.1 - 1.8 6.8 37.1 0.098 11.0 24.2 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein Fez1 PF06818.15 KFQ95481.1 - 3 8.2 32.8 1.2 9.5 15.8 2.1 1 1 1 2 2 2 0 Fez1 DUF16 PF01519.16 KFQ95481.1 - 4.1 7.9 26.4 11 6.6 2.0 3.7 1 1 2 3 3 3 0 Protein of unknown function DUF16 HAP1_N PF04849.13 KFQ95481.1 - 8.1 5.6 37.6 1.8e+04 -5.7 38.1 3.5 1 1 0 1 1 0 0 HAP1 N-terminal conserved region Fib_alpha PF08702.10 KFQ95481.1 - 9.3 6.4 27.1 0.44 10.7 10.9 3.1 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family DUF4462 PF14692.6 KFQ95482.1 - 0.083 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) RRM_1 PF00076.22 KFQ95483.1 - 5e-09 35.8 0.0 1.3e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFQ95483.1 - 0.0041 17.2 0.1 0.074 13.2 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KFQ95483.1 - 0.17 11.9 0.0 0.56 10.3 0.1 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif SesA PF17107.5 KFQ95483.1 - 3.5 7.8 11.3 10 6.3 3.1 2.8 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Cob_adeno_trans PF01923.18 KFQ95483.1 - 4 7.6 7.4 13 5.9 2.1 2.4 2 0 0 2 2 2 0 Cobalamin adenosyltransferase DUF1759 PF03564.15 KFQ95483.1 - 5.4 6.9 10.1 2.8 7.8 4.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1759) DnaJ PF00226.31 KFQ95484.1 - 0.00024 21.2 0.0 0.00038 20.5 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain FB_lectin PF07367.11 KFQ95484.1 - 0.083 12.8 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal fruit body lectin XRN1_D2_D3 PF18334.1 KFQ95485.1 - 1.9 8.7 7.1 1.2 9.4 0.1 2.6 2 1 1 3 3 3 0 Exoribonuclease Xrn1 D2/D3 domain MAP7 PF05672.11 KFQ95485.1 - 2.7 7.7 49.5 2.2 8.0 29.7 2.2 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family TNF PF00229.18 KFQ95486.1 - 2.5e-33 114.7 0.8 3.9e-33 114.1 0.8 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family DAGK_acc PF00609.19 KFQ95487.1 - 1.1e-52 178.6 0.0 2.1e-52 177.7 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KFQ95487.1 - 1.3e-26 92.7 0.1 4.5e-26 90.9 0.0 2.0 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 KFQ95487.1 - 2.8e-19 68.7 25.4 6.8e-10 38.7 5.2 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) SAM_2 PF07647.17 KFQ95487.1 - 4.3e-17 62.0 1.0 9.2e-17 60.9 0.2 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH PF00169.29 KFQ95487.1 - 4.4e-16 59.3 0.7 1e-15 58.1 0.7 1.7 1 0 0 1 1 1 1 PH domain SAM_1 PF00536.30 KFQ95487.1 - 5.9e-16 58.7 0.6 1.3e-15 57.6 0.6 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_8 PF15409.6 KFQ95487.1 - 0.00019 21.6 0.3 0.00041 20.6 0.3 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFQ95487.1 - 0.0006 20.2 2.0 0.0065 16.9 2.0 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain C1_2 PF03107.16 KFQ95487.1 - 0.0012 19.1 16.0 0.0054 17.0 5.7 2.6 2 0 0 2 2 2 2 C1 domain DUF883 PF05957.13 KFQ95487.1 - 0.07 13.7 1.4 0.24 12.0 1.4 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Mcp5_PH PF12814.7 KFQ95487.1 - 0.073 13.2 1.3 0.089 12.9 0.1 1.9 2 0 0 2 2 1 0 Meiotic cell cortex C-terminal pleckstrin homology Cdh1_DBD_1 PF18196.1 KFQ95487.1 - 0.12 12.7 5.5 0.41 11.0 5.5 1.9 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 SAM_4 PF18017.1 KFQ95487.1 - 0.17 11.9 0.0 0.42 10.6 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) V_ATPase_I PF01496.19 KFQ95487.1 - 5.4 4.8 7.7 10 3.9 7.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_5 PF07728.14 KFQ95488.1 - 1.6e-100 332.6 0.0 2e-39 134.8 0.0 3.6 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFQ95488.1 - 2.6e-07 31.2 2.5 0.64 10.4 0.0 5.9 5 1 0 6 6 6 2 AAA ATPase domain AAA PF00004.29 KFQ95488.1 - 1.9e-05 25.1 0.4 0.052 14.0 0.0 3.8 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 KFQ95488.1 - 3.9e-05 23.5 0.0 0.0095 15.8 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CbbQ_C PF08406.10 KFQ95488.1 - 7.1e-05 23.0 0.0 0.7 10.2 0.0 2.8 2 0 0 2 2 2 2 CbbQ/NirQ/NorQ C-terminal AAA_14 PF13173.6 KFQ95488.1 - 0.00011 22.2 0.0 0.18 11.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KFQ95488.1 - 0.0002 20.9 0.0 0.73 9.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_lid_7 PF17867.1 KFQ95488.1 - 0.00029 21.0 0.0 0.0042 17.3 0.2 2.7 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_22 PF13401.6 KFQ95488.1 - 0.00042 20.6 0.2 2.1 8.6 0.0 4.3 4 1 0 4 4 3 1 AAA domain Mg_chelatase PF01078.21 KFQ95488.1 - 0.00052 19.5 0.4 2.8 7.3 0.0 3.7 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI TniB PF05621.11 KFQ95488.1 - 0.00064 19.2 0.0 1.4 8.3 0.0 2.7 2 0 0 2 2 2 2 Bacterial TniB protein AAA_2 PF07724.14 KFQ95488.1 - 0.012 15.8 0.0 3.2 7.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) Roc PF08477.13 KFQ95488.1 - 0.019 15.2 0.7 2.1 8.6 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 KFQ95488.1 - 0.022 14.7 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NARP1 PF12569.8 KFQ95489.1 - 8.9e-222 737.6 21.3 8.9e-222 737.6 21.3 1.8 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 KFQ95489.1 - 3.1e-15 55.0 24.1 4.4e-05 23.3 0.1 8.4 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ95489.1 - 1.3e-14 53.6 2.9 0.1 13.5 0.0 9.6 7 2 2 9 9 9 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ95489.1 - 2.4e-12 46.0 24.9 0.00028 20.8 0.2 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ95489.1 - 3.6e-10 39.4 9.9 8.3e-06 25.4 0.1 5.8 5 0 0 5 5 5 2 TPR repeat TPR_1 PF00515.28 KFQ95489.1 - 5.1e-10 38.7 32.4 2e-05 24.2 0.6 8.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ95489.1 - 9.6e-10 39.0 6.4 0.016 15.8 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ95489.1 - 2.1e-08 34.5 11.4 0.041 14.4 0.3 5.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ95489.1 - 6.9e-08 32.7 14.0 1.5 9.1 0.1 7.8 5 2 1 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ95489.1 - 1.2e-07 31.8 19.8 0.00023 21.3 0.5 6.3 6 1 1 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KFQ95489.1 - 4.5e-06 26.1 1.4 4.5e-06 26.1 1.4 3.6 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ95489.1 - 9.7e-05 22.1 12.6 0.071 13.2 0.1 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFQ95489.1 - 0.0033 17.6 7.5 0.52 10.5 0.2 5.0 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ95489.1 - 0.004 17.0 7.9 31 4.6 0.1 6.3 5 0 0 5 5 5 0 Tetratricopeptide repeat CENP-N PF05238.13 KFQ95489.1 - 0.0092 15.3 1.7 0.014 14.7 1.7 1.3 1 0 0 1 1 1 1 Kinetochore protein CHL4 like DUF789 PF05623.12 KFQ95489.1 - 0.061 13.0 2.5 0.13 11.9 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF789) TPR_4 PF07721.14 KFQ95489.1 - 0.074 13.7 0.0 1.7e+02 3.3 0.1 4.5 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ95489.1 - 0.088 13.2 17.0 0.76 10.3 0.1 7.3 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFQ95489.1 - 0.13 12.9 10.5 32 5.4 0.1 6.1 6 1 0 6 6 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFQ95489.1 - 3.7 7.7 24.6 9.4 6.4 0.2 6.9 7 0 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat PCRF PF03462.18 KFQ95490.1 - 1.2e-50 172.1 0.6 1.2e-50 172.1 0.6 2.2 2 1 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KFQ95490.1 - 1.1e-38 131.8 4.1 1.1e-38 131.8 4.1 1.9 2 0 0 2 2 2 1 RF-1 domain HisKA PF00512.25 KFQ95490.1 - 0.13 12.3 6.1 0.43 10.7 0.2 3.5 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain CDI PF02234.19 KFQ95490.1 - 0.15 12.3 2.5 0.73 10.1 0.0 3.2 3 0 0 3 3 3 0 Cyclin-dependent kinase inhibitor zf-C4pol PF14260.6 KFQ95490.1 - 0.86 10.1 3.2 1.1 9.8 0.3 2.6 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DUF5101 PF17031.5 KFQ95490.1 - 2 8.5 8.7 0.33 11.1 0.2 3.0 2 1 0 3 3 3 0 Domain of unknown function (DUF5101) Myb_DNA-bind_3 PF12776.7 KFQ95490.1 - 2.1 9.4 6.6 3.4 8.7 0.3 3.0 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF4635 PF15466.6 KFQ95490.1 - 2.1 7.8 9.0 16 5.0 3.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4635) WW PF00397.26 KFQ95491.1 - 2.8e-20 72.1 17.9 4.6e-10 39.4 3.8 2.6 2 0 0 2 2 2 2 WW domain zf-U1 PF06220.12 KFQ95491.1 - 5.5e-15 54.8 0.7 9.2e-15 54.1 0.7 1.4 1 0 0 1 1 1 1 U1 zinc finger Glyco_hyd_101C PF17451.2 KFQ95491.1 - 0.0089 16.3 16.0 0.073 13.4 0.5 3.2 1 1 1 2 2 2 2 Glycosyl hydrolase 101 beta sandwich domain Elf-1_N PF12310.8 KFQ95492.1 - 3.6e-36 124.1 0.7 3.6e-36 124.1 0.7 2.3 2 0 0 2 2 2 1 Transcription factor protein N terminal Ets PF00178.22 KFQ95492.1 - 3.7e-34 117.0 1.2 6e-34 116.4 1.2 1.3 1 0 0 1 1 1 1 Ets-domain DUF5136 PF17199.4 KFQ95492.1 - 6.2 6.6 7.0 0.27 11.0 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5136) SGS PF05002.15 KFQ95493.1 - 2.7e-34 117.1 2.4 1.1e-33 115.2 2.4 2.1 1 0 0 1 1 1 1 SGS domain CS PF04969.16 KFQ95493.1 - 5.4e-18 65.8 1.7 5.4e-18 65.8 1.7 1.7 2 0 0 2 2 1 1 CS domain TPR_2 PF07719.17 KFQ95493.1 - 2e-07 30.6 10.5 2.9e-05 23.8 2.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ95493.1 - 3.7e-07 29.7 10.1 1.4e-05 24.7 2.6 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ95493.1 - 3.3e-06 27.1 4.3 0.0018 18.5 0.8 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ95493.1 - 4.8e-05 23.3 2.2 0.00097 19.2 1.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ95493.1 - 0.0013 18.4 7.1 0.049 13.3 0.5 2.8 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.6 KFQ95493.1 - 0.0013 19.4 1.8 0.13 13.1 0.2 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ95493.1 - 0.013 16.1 4.1 0.043 14.5 1.5 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Tim29 PF10171.9 KFQ95493.1 - 0.016 14.7 0.1 0.03 13.8 0.1 1.5 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 DUF2018 PF09442.10 KFQ95493.1 - 0.04 14.9 0.4 0.22 12.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) TPR_12 PF13424.6 KFQ95493.1 - 0.071 13.4 3.4 1.5 9.1 0.8 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 KFQ95493.1 - 0.071 13.4 3.4 0.17 12.2 1.1 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ95493.1 - 0.13 12.5 2.6 0.24 11.7 2.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KFQ95493.1 - 0.17 12.0 0.4 1.1 9.4 0.1 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat Methyltransf_32 PF13679.6 KFQ95494.1 - 3.2e-32 111.7 10.3 4.3e-30 104.8 10.3 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFQ95494.1 - 0.00019 22.1 0.0 0.00082 20.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFQ95494.1 - 0.00093 19.1 0.1 0.0045 16.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFQ95494.1 - 0.0011 18.8 0.0 0.0034 17.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFQ95494.1 - 0.002 18.7 0.0 0.024 15.3 0.0 2.6 2 1 1 3 3 3 1 Methyltransferase domain MTS PF05175.14 KFQ95494.1 - 0.02 14.5 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 KFQ95494.1 - 0.021 14.8 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KFQ95494.1 - 0.052 14.3 0.0 0.14 12.9 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 KFQ95494.1 - 0.078 12.6 0.0 0.18 11.4 0.0 1.6 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW NapE PF06796.11 KFQ95494.1 - 0.11 12.1 0.0 0.58 9.7 0.0 2.2 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE DUF3294 PF07957.11 KFQ95494.1 - 0.11 12.3 1.2 0.46 10.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3294) rRNA_processing PF08524.11 KFQ95495.1 - 2.3e-13 50.4 38.2 1.5e-12 47.8 38.2 1.9 1 1 0 1 1 1 1 rRNA processing HTH_psq PF05225.16 KFQ95495.1 - 0.03 14.1 0.0 0.077 12.7 0.0 1.8 1 0 0 1 1 1 0 helix-turn-helix, Psq domain DUF4554 PF15091.6 KFQ95495.1 - 0.3 9.9 8.7 0.31 9.9 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) OrfB_IS605 PF01385.19 KFQ95495.1 - 1.5 9.1 17.5 6.3 7.1 0.7 2.3 2 0 0 2 2 2 0 Probable transposase AMP-binding PF00501.28 KFQ95496.1 - 8.5e-83 278.3 0.0 1e-82 278.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFQ95496.1 - 3.2e-20 72.9 1.4 5.8e-20 72.0 0.5 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KFQ95496.1 - 0.042 13.8 0.3 0.15 12.0 0.3 2.0 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus PDZ PF00595.24 KFQ95497.1 - 7.5e-21 74.3 0.4 1.2e-20 73.6 0.4 1.3 1 0 0 1 1 1 1 PDZ domain L27 PF02828.16 KFQ95497.1 - 1.1e-14 53.9 0.1 2.6e-14 52.7 0.0 1.7 2 0 0 2 2 2 1 L27 domain PDZ_6 PF17820.1 KFQ95497.1 - 1.1e-13 50.7 0.3 3.4e-13 49.2 0.1 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KFQ95497.1 - 0.00068 19.9 0.1 0.0015 18.8 0.0 1.5 2 0 0 2 2 2 1 PDZ domain Basic PF01586.16 KFQ95498.1 - 4.5e-24 85.4 0.1 1.5e-23 83.7 0.0 1.9 2 0 0 2 2 2 1 Myogenic Basic domain HLH PF00010.26 KFQ95498.1 - 4.5e-13 48.9 6.2 7.3e-13 48.3 6.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Myf5 PF12232.8 KFQ95498.1 - 0.016 15.9 6.0 0.016 15.9 6.0 1.9 2 0 0 2 2 2 0 Myogenic determination factor 5 fn3 PF00041.21 KFQ95500.1 - 0.031 14.6 0.6 0.25 11.7 0.6 2.0 1 1 0 1 1 1 0 Fibronectin type III domain DUF4680 PF15730.5 KFQ95500.1 - 0.057 13.8 0.0 0.067 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) VWD PF00094.25 KFQ95501.1 - 2.1e-95 317.3 14.9 2.9e-26 92.6 0.3 4.6 4 0 0 4 4 4 4 von Willebrand factor type D domain C8 PF08742.11 KFQ95501.1 - 3e-44 149.3 55.9 6.9e-16 58.4 3.7 10.2 10 2 0 10 10 10 4 C8 domain TIL PF01826.17 KFQ95501.1 - 4.6e-14 52.4 70.8 1.2e-06 28.6 14.8 17.1 14 3 3 17 17 17 5 Trypsin Inhibitor like cysteine rich domain AbfB PF05270.13 KFQ95501.1 - 1.9e-08 34.4 0.1 4.1e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain Ribosomal_S9 PF00380.19 KFQ95502.1 - 1.9e-32 112.3 0.1 2.2e-32 112.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 PRKG1_interact PF15898.5 KFQ95503.1 - 2.2e-33 115.2 14.6 2.2e-33 115.2 14.6 6.4 5 2 1 6 6 6 1 cGMP-dependent protein kinase interacting domain Ank_4 PF13637.6 KFQ95503.1 - 4.4e-29 100.5 0.4 5.6e-12 45.9 0.0 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFQ95503.1 - 2e-27 95.6 0.5 4.4e-13 49.6 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFQ95503.1 - 1.3e-23 82.7 3.2 3.4e-07 30.4 0.0 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KFQ95503.1 - 5e-20 71.0 0.3 0.0031 17.9 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KFQ95503.1 - 3.1e-16 57.8 1.7 0.017 15.6 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat FPP PF05911.11 KFQ95504.1 - 0.0003 19.1 9.8 0.00052 18.4 9.8 1.3 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil PRKG1_interact PF15898.5 KFQ95504.1 - 0.0013 19.6 10.6 0.0013 19.6 10.6 2.7 2 1 0 2 2 2 1 cGMP-dependent protein kinase interacting domain FAM76 PF16046.5 KFQ95504.1 - 0.0015 18.0 5.3 0.0017 17.7 5.3 1.0 1 0 0 1 1 1 1 FAM76 protein UPF0242 PF06785.11 KFQ95504.1 - 0.0016 18.6 7.1 0.0016 18.6 7.1 1.5 2 0 0 2 2 1 1 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 KFQ95504.1 - 0.0016 18.4 11.4 0.0016 18.4 11.4 1.8 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 KFQ95504.1 - 0.004 17.4 8.8 0.0084 16.3 8.8 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding FlxA PF14282.6 KFQ95504.1 - 0.0052 16.8 4.0 0.0052 16.8 4.0 2.2 2 0 0 2 2 2 1 FlxA-like protein DUF812 PF05667.11 KFQ95504.1 - 0.0057 15.6 6.6 0.007 15.3 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) APG6_N PF17675.1 KFQ95504.1 - 0.01 16.3 8.4 0.01 16.3 8.4 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region ATG16 PF08614.11 KFQ95504.1 - 0.017 15.3 22.2 0.034 14.4 22.2 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Miff PF05644.11 KFQ95504.1 - 0.024 14.3 5.0 0.03 14.0 5.0 1.0 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff DUF1706 PF08020.11 KFQ95504.1 - 0.049 13.5 0.9 0.049 13.5 0.9 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF1706) TSC22 PF01166.18 KFQ95504.1 - 0.091 13.1 14.3 0.13 12.6 3.8 2.4 1 1 1 2 2 2 0 TSC-22/dip/bun family Prominin PF05478.11 KFQ95504.1 - 0.12 10.3 2.3 0.15 10.0 2.3 1.0 1 0 0 1 1 1 0 Prominin Spc7 PF08317.11 KFQ95504.1 - 0.13 11.1 9.5 0.22 10.4 9.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4094 PF13334.6 KFQ95504.1 - 0.17 12.3 0.0 0.17 12.3 0.0 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4094) DUF1664 PF07889.12 KFQ95504.1 - 0.19 11.8 3.0 0.31 11.1 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FapA PF03961.13 KFQ95504.1 - 0.2 10.3 5.2 0.26 9.9 5.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A YabA PF06156.13 KFQ95504.1 - 0.28 11.8 9.2 0.21 12.3 4.1 2.3 1 1 1 2 2 2 0 Initiation control protein YabA V_ATPase_I PF01496.19 KFQ95504.1 - 0.31 8.9 3.6 0.48 8.3 3.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fungal_TACC PF12709.7 KFQ95504.1 - 0.39 11.2 10.7 0.79 10.2 1.6 2.6 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins TolA_bind_tri PF16331.5 KFQ95504.1 - 0.51 10.5 12.5 2.6 8.2 12.5 2.0 1 1 0 1 1 1 0 TolA binding protein trimerisation DUF724 PF05266.14 KFQ95504.1 - 1.1 9.1 9.1 0.058 13.2 3.8 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF724) DUF4140 PF13600.6 KFQ95504.1 - 1.1 9.8 15.3 1.6 9.2 1.3 2.9 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) HAUS6_N PF14661.6 KFQ95504.1 - 1.1 8.8 6.6 0.16 11.5 2.7 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Tubulin_3 PF14881.6 KFQ95504.1 - 1.1 8.9 4.0 0.87 9.2 2.2 1.7 2 0 0 2 2 2 0 Tubulin domain FlaC_arch PF05377.11 KFQ95504.1 - 1.7 9.1 12.1 2.3 8.7 3.8 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) AAA_15 PF13175.6 KFQ95504.1 - 1.7 8.2 9.0 2.2 7.9 9.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain HAP1_N PF04849.13 KFQ95504.1 - 1.8 7.7 17.4 1.3 8.2 2.6 2.6 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Fmp27_WPPW PF10359.9 KFQ95504.1 - 2.1 7.1 10.0 0.12 11.2 4.8 1.4 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain CENP-H PF05837.12 KFQ95504.1 - 2.4 8.6 13.7 0.33 11.4 1.7 2.6 2 1 2 4 4 3 0 Centromere protein H (CENP-H) bZIP_1 PF00170.21 KFQ95504.1 - 2.5 8.3 19.0 0.36 10.9 4.6 2.6 2 1 1 3 3 2 0 bZIP transcription factor Med21 PF11221.8 KFQ95504.1 - 3.2 8.0 18.0 1.7 8.9 1.8 2.7 2 1 1 3 3 3 0 Subunit 21 of Mediator complex Cep57_CLD_2 PF14197.6 KFQ95504.1 - 3.8 7.7 15.8 14 5.8 15.9 1.9 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Nnf1 PF03980.14 KFQ95504.1 - 6.4 7.2 15.0 1.5 9.3 1.8 2.6 2 1 1 3 3 3 0 Nnf1 DivIC PF04977.15 KFQ95504.1 - 7.3 6.4 20.3 0.45 10.3 3.6 2.8 2 1 1 3 3 3 0 Septum formation initiator CorA PF01544.18 KFQ95504.1 - 9.6 5.4 7.9 22 4.3 7.9 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein C2 PF00168.30 KFQ95506.1 - 6e-55 183.9 0.4 8.9e-27 93.4 0.0 2.3 2 0 0 2 2 2 2 C2 domain Comm PF15957.5 KFQ95506.1 - 0.0015 18.9 0.0 0.0042 17.4 0.0 1.8 1 0 0 1 1 1 1 Commissureless CEP76-C2 PF15627.6 KFQ95506.1 - 0.0022 17.6 0.0 1 8.9 0.0 2.3 1 1 1 2 2 2 2 CEP76 C2 domain Shisa PF13908.6 KFQ95506.1 - 0.029 14.6 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator MAP17 PF15807.5 KFQ95506.1 - 0.031 14.5 0.1 0.075 13.3 0.1 1.6 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 LYRIC PF15686.5 KFQ95506.1 - 0.042 13.4 0.0 0.042 13.4 0.0 1.6 2 0 0 2 2 2 0 Lysine-rich CEACAM1 co-isolated protein family DUF1258 PF06869.12 KFQ95506.1 - 0.052 13.0 0.3 0.096 12.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) DOCK-C2 PF14429.6 KFQ95506.1 - 0.08 12.7 0.3 7.8 6.3 0.0 2.2 2 0 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins EphA2_TM PF14575.6 KFQ95506.1 - 0.096 13.6 0.0 0.22 12.4 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orthopox_F7 PF05813.12 KFQ95506.1 - 0.97 9.6 4.5 3.1 8.0 3.9 2.1 2 0 0 2 2 2 0 Orthopoxvirus F7 protein CH PF00307.31 KFQ95507.1 - 8.8e-15 54.8 0.7 1.6e-14 54.0 0.1 1.8 2 0 0 2 2 1 1 Calponin homology (CH) domain AAA_14 PF13173.6 KFQ95507.1 - 6.8e-06 26.1 0.0 2e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFQ95507.1 - 1.6e-05 25.3 0.1 5.9e-05 23.5 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFQ95507.1 - 2.5e-05 24.6 0.2 0.0014 18.9 0.2 2.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFQ95507.1 - 5.4e-05 23.6 0.2 0.034 14.5 0.0 3.0 1 1 1 2 2 2 1 AAA ATPase domain CAMSAP_CH PF11971.8 KFQ95507.1 - 0.00084 19.1 0.2 0.0083 15.9 0.0 2.4 2 0 0 2 2 2 1 CAMSAP CH domain RNA_helicase PF00910.22 KFQ95507.1 - 0.0011 19.3 0.0 0.0059 17.0 0.0 2.3 2 0 0 2 2 1 1 RNA helicase PhoH PF02562.16 KFQ95507.1 - 0.0029 17.1 0.0 0.0063 16.0 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_18 PF13238.6 KFQ95507.1 - 0.0052 17.3 0.0 0.026 15.1 0.0 2.3 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 KFQ95507.1 - 0.0085 15.8 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein ResIII PF04851.15 KFQ95507.1 - 0.0091 16.0 0.2 0.29 11.1 0.1 2.8 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 KFQ95507.1 - 0.011 15.2 0.0 0.14 11.5 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KFQ95507.1 - 0.014 15.6 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KFQ95507.1 - 0.019 15.0 0.0 0.056 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 KFQ95507.1 - 0.019 14.0 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 KFQ95507.1 - 0.021 14.6 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KFQ95507.1 - 0.028 14.6 0.0 0.07 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) CH_2 PF06294.11 KFQ95507.1 - 0.031 14.4 0.2 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 CH-like domain in sperm protein AAA_25 PF13481.6 KFQ95507.1 - 0.032 13.8 0.0 0.12 11.9 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.6 KFQ95507.1 - 0.045 14.1 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFQ95507.1 - 0.063 13.2 0.0 1.1 9.2 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 KFQ95507.1 - 0.073 13.0 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 KFQ95507.1 - 0.16 11.5 0.0 0.35 10.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DivIC PF04977.15 KFQ95507.1 - 0.21 11.4 12.5 2 8.3 0.1 4.4 4 0 0 4 4 4 0 Septum formation initiator DUF4201 PF13870.6 KFQ95507.1 - 2.1 8.1 16.5 0.72 9.6 4.5 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) E2F_TDP PF02319.20 KFQ95508.1 - 1.3e-42 143.6 1.5 9.4e-21 73.7 0.0 2.4 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 KFQ95508.1 - 0.00014 21.7 0.0 0.0012 18.7 0.0 2.3 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.12 KFQ95508.1 - 0.0013 18.9 0.0 0.82 9.9 0.0 2.4 2 0 0 2 2 2 2 B-block binding subunit of TFIIIC Cdc6_C PF09079.11 KFQ95508.1 - 0.11 12.5 0.0 8.1 6.5 0.0 2.4 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain LIM PF00412.22 KFQ95509.1 - 1.7e-30 105.0 27.3 2.7e-17 62.8 5.5 2.1 2 0 0 2 2 2 2 LIM domain DUF4428 PF14471.6 KFQ95509.1 - 0.012 15.5 9.4 0.035 14.0 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) zf_UBZ PF18439.1 KFQ95509.1 - 0.072 12.7 12.7 0.36 10.5 0.5 4.2 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2H2_12 PF18658.1 KFQ95509.1 - 0.94 9.1 6.0 2.8 7.6 0.8 2.9 3 0 0 3 3 3 0 Zinc-finger C2H2-type DHHC PF01529.20 KFQ95510.1 - 1.8e-35 122.0 20.9 1.8e-35 122.0 20.9 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.6 KFQ95510.1 - 2.6e-32 110.8 6.1 8e-09 35.9 0.0 4.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFQ95510.1 - 8.2e-31 106.4 0.2 3.6e-16 59.5 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFQ95510.1 - 7e-29 99.5 2.1 6.5e-07 29.5 0.2 5.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ95510.1 - 1e-28 96.2 1.5 4.5e-05 23.5 0.1 7.5 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 KFQ95510.1 - 2.3e-23 81.5 2.3 5.6e-06 26.6 0.4 6.0 6 0 0 6 6 6 5 Ankyrin repeat Oxysterol_BP PF01237.18 KFQ95511.1 - 2.1e-95 319.7 4.4 5.6e-93 311.7 4.4 2.5 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 KFQ95511.1 - 3.3e-10 40.4 0.0 1.2e-09 38.6 0.0 2.0 1 0 0 1 1 1 1 PH domain Cpn60_TCP1 PF00118.24 KFQ95512.1 - 1.4e-13 50.3 0.0 5.5e-06 25.3 0.0 2.3 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family DNA_photolyase PF00875.18 KFQ95512.1 - 0.036 14.1 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 DNA photolyase NAP PF00956.18 KFQ95513.1 - 4.5e-114 380.2 7.0 6.7e-114 379.6 7.0 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) sCache_3_3 PF17202.4 KFQ95513.1 - 0.059 13.8 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Single cache domain 3 ING PF12998.7 KFQ95513.1 - 0.064 13.8 2.1 0.34 11.5 2.1 2.1 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding KH_8 PF17903.1 KFQ95514.1 - 3.8e-29 100.6 0.0 3.8e-29 100.6 0.0 2.6 3 0 0 3 3 3 1 Krr1 KH1 domain KH_1 PF00013.29 KFQ95514.1 - 8e-05 22.4 0.3 0.0016 18.2 0.0 2.5 2 0 0 2 2 2 1 KH domain KH_4 PF13083.6 KFQ95514.1 - 0.055 13.3 0.6 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 KH domain CAP PF00188.26 KFQ95515.1 - 9.5e-26 91.1 3.8 1.2e-25 90.8 3.8 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 KFQ95516.1 - 8.1e-26 91.3 1.8 9.9e-26 91.0 1.8 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 KFQ95517.1 - 4.1e-13 50.3 5.9 6.6e-13 49.6 5.9 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family RecR PF02132.15 KFQ95517.1 - 3 7.5 9.4 39 3.9 0.1 3.2 2 1 0 2 2 2 0 RecR protein RIC3 PF15361.6 KFQ95518.1 - 9.5e-18 65.0 0.4 1.1e-17 64.7 0.4 1.1 1 0 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 EF-hand_6 PF13405.6 KFQ95519.1 - 7.9e-08 31.6 1.8 0.00032 20.4 0.2 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 KFQ95519.1 - 2.4e-05 24.7 2.6 0.00011 22.6 0.8 2.9 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFQ95519.1 - 2.9e-05 23.3 1.1 0.00032 20.0 0.1 3.0 4 0 0 4 4 4 1 EF hand DUF1126 PF06565.12 KFQ95519.1 - 0.00028 20.6 0.1 0.00064 19.5 0.1 1.5 1 0 0 1 1 1 1 DUF1126 PH-like domain EF-hand_5 PF13202.6 KFQ95519.1 - 0.037 13.5 0.2 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 EF hand Ion_trans PF00520.31 KFQ95520.1 - 1.3e-43 149.0 15.1 1.6e-43 148.7 15.1 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFQ95520.1 - 2.6e-11 43.3 2.7 2.6e-11 43.3 2.7 2.6 3 0 0 3 3 3 1 Ion channel BTB_2 PF02214.22 KFQ95520.1 - 3.9e-10 40.0 0.0 1.1e-09 38.5 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KFQ95520.1 - 0.046 13.8 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain Lig_chan PF00060.26 KFQ95520.1 - 0.098 12.5 1.7 1.7 8.5 0.2 2.3 2 0 0 2 2 2 0 Ligand-gated ion channel Peptidase_M1 PF01433.20 KFQ95521.1 - 6.5e-81 271.1 1.0 1.2e-80 270.2 1.0 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KFQ95521.1 - 1.2e-75 255.0 3.7 2.1e-75 254.2 3.7 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KFQ95521.1 - 1e-28 100.8 0.3 1.8e-28 100.0 0.3 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Biopterin_H PF00351.21 KFQ95522.1 - 3e-175 582.0 0.1 3.6e-175 581.8 0.1 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase Ras PF00071.22 KFQ95524.1 - 1.5e-43 148.2 0.1 1.8e-43 148.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ95524.1 - 1.7e-22 79.9 0.1 3.6e-22 78.8 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ95524.1 - 1e-09 38.1 0.1 1.2e-09 37.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFQ95524.1 - 0.00013 21.6 0.0 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFQ95524.1 - 0.003 17.5 0.1 0.0056 16.6 0.1 1.4 1 1 0 1 1 1 1 RsgA GTPase PduV-EutP PF10662.9 KFQ95524.1 - 0.039 13.7 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF92 PF01940.16 KFQ95526.1 - 1.2e-78 263.8 3.4 1.9e-78 263.2 3.4 1.3 1 0 0 1 1 1 1 Integral membrane protein DUF92 zf-C3H1 PF10650.9 KFQ95527.1 - 6.5e-09 35.4 4.3 1.5e-08 34.2 4.3 1.6 1 0 0 1 1 1 1 Putative zinc-finger domain TPR_17 PF13431.6 KFQ95527.1 - 2.1e-06 27.7 5.7 0.14 12.6 0.5 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ95527.1 - 9.9e-06 26.0 6.7 0.26 12.2 0.0 6.9 7 1 2 9 9 9 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ95527.1 - 1.5e-05 25.4 6.6 0.35 11.4 0.0 6.0 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.6 KFQ95527.1 - 0.00089 19.5 0.0 0.048 14.0 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat ChAPs PF09295.10 KFQ95527.1 - 0.0027 16.8 1.2 0.62 9.0 0.1 3.4 2 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_1 PF00515.28 KFQ95527.1 - 0.12 12.3 1.1 13 5.8 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ95527.1 - 0.18 11.5 6.5 5.5 6.8 0.2 3.7 4 1 1 5 5 5 0 TPR repeat LRR_8 PF13855.6 KFQ95528.1 - 1.6e-106 348.0 80.1 3.1e-15 55.7 0.9 8.5 2 2 10 12 12 12 12 Leucine rich repeat LRR_4 PF12799.7 KFQ95528.1 - 2.8e-41 138.8 36.9 3.4e-06 27.3 0.4 9.7 6 1 5 11 11 11 11 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFQ95528.1 - 3.5e-36 124.0 0.0 5.2e-13 49.1 0.0 5.3 3 1 2 6 6 6 4 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFQ95528.1 - 1.6e-15 57.1 10.0 0.0029 17.1 0.4 5.4 1 1 3 5 5 5 5 Leucine-rich repeat LRR_1 PF00560.33 KFQ95528.1 - 2.3e-12 45.6 37.1 0.99 10.2 0.0 14.3 13 2 0 13 13 13 4 Leucine Rich Repeat 7tm_1 PF00001.21 KFQ95528.1 - 2.9e-11 43.2 15.2 5.9e-11 42.2 15.2 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFQ95528.1 - 0.00016 21.4 8.6 0.00016 21.4 8.6 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2207 PF09972.9 KFQ95528.1 - 5.2 5.7 6.5 24 3.5 0.0 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Y_phosphatase PF00102.27 KFQ95529.1 - 5.2e-75 252.0 0.1 5.2e-75 252.0 0.1 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFQ95529.1 - 0.00019 21.5 0.0 0.00049 20.1 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 KFQ95529.1 - 0.00045 20.0 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CyRPA PF18638.1 KFQ95529.1 - 0.02 14.0 0.1 0.033 13.3 0.1 1.2 1 0 0 1 1 1 0 Cysteine-Rich Protective Antigen 6 bladed domain PTPlike_phytase PF14566.6 KFQ95529.1 - 0.024 14.7 0.2 0.059 13.5 0.0 1.7 2 0 0 2 2 2 0 Inositol hexakisphosphate WBP-1 PF11669.8 KFQ95529.1 - 0.061 14.0 0.2 0.15 12.7 0.2 1.6 1 0 0 1 1 1 0 WW domain-binding protein 1 DUF3149 PF11346.8 KFQ95529.1 - 1.1 9.0 4.1 2.2 8.0 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) CaKB PF03185.15 KFQ95530.1 - 5.2e-56 189.4 0.2 5.9e-56 189.2 0.2 1.0 1 0 0 1 1 1 1 Calcium-activated potassium channel, beta subunit LapA_dom PF06305.11 KFQ95530.1 - 0.11 12.4 0.4 0.16 11.8 0.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain NOT2_3_5 PF04153.18 KFQ95531.1 - 3.2e-32 111.4 0.2 6.1e-32 110.5 0.2 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family MRF_C2 PF13888.6 KFQ95532.1 - 3.1e-49 166.4 2.1 3.1e-49 166.4 2.1 1.9 2 0 0 2 2 2 1 Myelin gene regulatory factor C-terminal domain 2 NDT80_PhoG PF05224.12 KFQ95532.1 - 2.3e-27 96.4 0.5 3.3e-26 92.6 0.5 2.3 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family MRF_C1 PF13887.6 KFQ95532.1 - 1.8e-21 75.0 0.6 5.4e-21 73.5 0.6 1.9 1 0 0 1 1 1 1 Myelin gene regulatory factor -C-terminal domain 1 Peptidase_S74 PF13884.6 KFQ95532.1 - 7.8e-14 51.7 0.1 1.5e-13 50.8 0.1 1.5 1 0 0 1 1 1 1 Chaperone of endosialidase Sec2p PF06428.11 KFQ95533.1 - 1.9e-08 34.2 9.3 1.9e-08 34.2 9.3 2.1 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p FAM76 PF16046.5 KFQ95533.1 - 0.0037 16.7 3.3 0.0061 15.9 3.3 1.3 1 0 0 1 1 1 1 FAM76 protein T3SSipB PF16535.5 KFQ95533.1 - 0.035 14.6 4.6 0.061 13.8 4.6 1.4 1 0 0 1 1 1 0 Type III cell invasion protein SipB UPF0242 PF06785.11 KFQ95533.1 - 0.069 13.3 6.3 0.11 12.6 6.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 KFQ95533.1 - 0.087 11.7 8.5 0.14 11.0 8.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.8 KFQ95533.1 - 0.093 10.2 7.9 0.14 9.6 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GCN5L1 PF06320.13 KFQ95533.1 - 0.11 12.7 4.4 0.22 11.7 4.4 1.4 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) DUF3987 PF13148.6 KFQ95533.1 - 0.21 10.6 3.3 0.31 10.0 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) GAS PF13851.6 KFQ95533.1 - 0.27 10.6 10.3 0.49 9.7 10.3 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FapA PF03961.13 KFQ95533.1 - 0.31 9.6 2.6 0.43 9.1 2.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF5082 PF16888.5 KFQ95533.1 - 0.56 10.5 7.9 5.9 7.2 2.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Cauli_AT PF03233.13 KFQ95533.1 - 0.68 9.8 3.7 13 5.7 1.2 2.6 1 1 2 3 3 3 0 Aphid transmission protein TPR_MLP1_2 PF07926.12 KFQ95533.1 - 0.77 9.8 14.4 1.8 8.6 14.4 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 KFQ95533.1 - 0.83 9.9 11.3 2.9 8.1 11.3 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CC2-LZ PF16516.5 KFQ95533.1 - 1.4 9.4 11.8 1.9 8.9 3.7 2.5 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator PRKG1_interact PF15898.5 KFQ95533.1 - 1.4 9.8 8.8 3.3 8.6 8.8 1.6 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain CENP-H PF05837.12 KFQ95533.1 - 2 8.9 9.5 4.6 7.7 9.5 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ATG16 PF08614.11 KFQ95533.1 - 6.2 7.0 15.1 36 4.5 6.4 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 KFQ95533.1 - 7.4 5.8 8.2 26 4.0 8.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Bestrophin PF01062.21 KFQ95534.1 - 1.3e-104 349.8 5.3 2.1e-104 349.1 5.3 1.3 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Autophagy_N PF03986.13 KFQ95534.1 - 0.0064 16.4 0.2 0.012 15.5 0.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Asp PF00026.23 KFQ95535.1 - 7e-115 383.8 0.1 8.1e-115 383.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFQ95535.1 - 2.9e-12 47.2 1.1 5.3e-10 39.8 1.1 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.12 KFQ95535.1 - 2.7e-09 36.7 1.4 4.8e-09 35.9 1.4 1.4 1 0 0 1 1 1 1 A1 Propeptide TAXi_C PF14541.6 KFQ95535.1 - 0.00085 19.1 0.0 0.0022 17.8 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal LRR_8 PF13855.6 KFQ95536.1 - 1.6e-15 56.6 44.9 9.7e-06 25.3 7.3 4.2 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KFQ95536.1 - 5.8e-15 55.2 21.6 5.6e-05 23.4 0.0 4.4 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) RsmF_methylt_CI PF17126.5 KFQ95536.1 - 0.067 13.3 0.5 13 5.9 0.0 3.3 2 1 2 4 4 4 0 RsmF rRNA methyltransferase first C-terminal domain LRR_1 PF00560.33 KFQ95536.1 - 0.075 13.6 24.8 2.4 9.0 0.2 6.5 6 1 0 6 6 6 0 Leucine Rich Repeat Rota_NS6 PF04866.12 KFQ95536.1 - 0.26 11.5 2.1 1.3 9.3 0.3 2.4 1 1 1 2 2 2 0 Rotavirus non-structural protein 6 Cpn60_TCP1 PF00118.24 KFQ95537.1 - 3.5e-147 491.0 13.5 4e-147 490.8 13.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2529 PF10740.9 KFQ95537.1 - 0.0037 16.9 0.2 0.015 14.9 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF2529) Ribosomal_S13 PF00416.22 KFQ95537.1 - 0.088 13.2 1.2 0.31 11.4 0.3 2.4 2 0 0 2 2 2 0 Ribosomal protein S13/S18 DUF5442 PF17514.2 KFQ95537.1 - 0.15 12.2 0.2 0.31 11.2 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5442) IRS PF02174.17 KFQ95538.1 - 8.1e-25 86.6 0.1 1.9e-24 85.4 0.1 1.6 1 0 0 1 1 1 1 PTB domain (IRS-1 type) YEATS PF03366.16 KFQ95539.1 - 3.8e-27 94.1 0.2 7e-27 93.2 0.2 1.5 1 0 0 1 1 1 1 YEATS family SOGA PF11365.8 KFQ95539.1 - 0.0053 17.8 3.0 0.009 17.1 3.0 1.4 1 0 0 1 1 1 1 Protein SOGA FapA PF03961.13 KFQ95539.1 - 0.077 11.6 1.4 0.09 11.4 1.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A RIC3 PF15361.6 KFQ95539.1 - 0.12 12.8 1.0 0.18 12.2 1.0 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF1664 PF07889.12 KFQ95539.1 - 0.14 12.2 1.1 0.21 11.6 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DivIC PF04977.15 KFQ95539.1 - 0.48 10.2 3.0 0.98 9.2 3.0 1.6 1 0 0 1 1 1 0 Septum formation initiator RRM_1 PF00076.22 KFQ95540.1 - 5.1e-07 29.4 0.0 9e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc PF12871.7 KFQ95540.1 - 0.0038 17.8 50.1 0.0088 16.6 50.1 1.6 1 0 0 1 1 1 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Peptidase_M14 PF00246.24 KFQ95541.1 - 1.3e-76 258.2 0.0 1.7e-76 257.8 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 KFQ95541.1 - 8e-11 42.1 0.0 1.5e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain AstE_AspA PF04952.14 KFQ95541.1 - 9.6e-08 31.4 0.1 1.7e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family CarbopepD_reg_2 PF13715.6 KFQ95541.1 - 2.5e-06 27.4 0.0 5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 CarboxypepD_reg-like domain Dioxygenase_C PF00775.21 KFQ95541.1 - 0.019 14.4 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Dioxygenase Big_1 PF02369.16 KFQ95541.1 - 0.13 12.2 0.3 0.32 11.0 0.3 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) zf-C3HC4_3 PF13920.6 KFQ95542.1 - 2.6e-13 49.6 9.6 2.6e-13 49.6 9.6 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SWIB PF02201.18 KFQ95542.1 - 1.7e-10 40.6 0.1 4.3e-10 39.3 0.0 1.7 2 0 0 2 2 2 1 SWIB/MDM2 domain zf-RanBP PF00641.18 KFQ95542.1 - 6.5e-09 35.0 1.9 6.5e-09 35.0 1.9 2.6 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-RING_2 PF13639.6 KFQ95542.1 - 0.016 15.6 9.5 0.016 15.6 9.5 2.2 2 0 0 2 2 2 0 Ring finger domain zf-FPG_IleRS PF06827.14 KFQ95542.1 - 0.094 12.6 0.1 0.094 12.6 0.1 3.8 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS DZR PF12773.7 KFQ95542.1 - 0.12 12.4 14.9 0.59 10.2 1.9 3.2 3 0 0 3 3 3 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 KFQ95542.1 - 0.62 9.9 9.3 0.16 11.8 2.4 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 KFQ95542.1 - 5.5 7.1 12.2 1 9.4 4.8 2.8 2 0 0 2 2 2 0 zinc-ribbons Nup84_Nup100 PF04121.13 KFQ95543.1 - 7.1e-216 718.7 17.6 8.3e-216 718.5 17.6 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Ras PF00071.22 KFQ95544.1 - 6.2e-40 136.4 0.5 7.1e-40 136.3 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ95544.1 - 7.1e-11 42.4 0.0 1.1e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KFQ95544.1 - 0.0001 21.9 0.1 0.00015 21.4 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KFQ95544.1 - 0.00025 20.6 0.3 0.00025 20.5 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MDM1 PF15501.6 KFQ95545.1 - 3.7e-160 534.7 39.1 2.1e-159 532.3 39.1 2.0 1 1 0 1 1 1 1 Nuclear protein MDM1 BSP_II PF05432.11 KFQ95545.1 - 0.0013 18.5 5.3 0.0013 18.5 5.3 2.0 3 0 0 3 3 3 1 Bone sialoprotein II (BSP-II) KCT2 PF17818.1 KFQ95545.1 - 0.043 13.9 3.5 0.13 12.4 3.5 1.8 1 0 0 1 1 1 0 Keratinocyte-associated gene product Roughex PF06020.11 KFQ95545.1 - 7.8 5.5 16.2 0.69 8.9 8.5 2.1 2 0 0 2 2 2 0 Drosophila roughex protein IL22 PF14565.6 KFQ95546.1 - 4.5e-76 253.8 2.8 5.2e-76 253.6 2.8 1.0 1 0 0 1 1 1 1 Interleukin 22 IL-10-related T-cell-derived-inducible factor IL10 PF00726.17 KFQ95546.1 - 9e-06 25.3 0.5 9.9e-06 25.2 0.5 1.1 1 0 0 1 1 1 1 Interleukin 10 CPL PF08144.11 KFQ95546.1 - 0.026 14.9 0.1 0.039 14.3 0.1 1.2 1 0 0 1 1 1 0 CPL (NUC119) domain CENP-F_leu_zip PF10473.9 KFQ95546.1 - 0.028 14.4 0.3 0.047 13.7 0.3 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Col_cuticle_N PF01484.17 KFQ95546.1 - 0.21 11.7 1.7 4.4 7.4 1.5 2.3 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain IL10 PF00726.17 KFQ95547.1 - 3.7e-09 36.3 0.0 6e-09 35.6 0.0 1.5 1 1 0 1 1 1 1 Interleukin 10 IL22 PF14565.6 KFQ95547.1 - 2.4e-05 24.6 0.0 4.2e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 Interleukin 22 IL-10-related T-cell-derived-inducible factor IFN-gamma PF00714.17 KFQ95549.1 - 3.4e-28 98.2 1.4 4.3e-28 97.9 1.4 1.1 1 0 0 1 1 1 1 Interferon gamma Fib_alpha PF08702.10 KFQ95549.1 - 0.055 13.7 4.4 0.071 13.3 0.6 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TIP120 PF08623.10 KFQ95550.1 - 3.2e-67 225.5 8.8 7.1e-65 217.9 0.8 5.6 4 1 2 6 6 6 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 KFQ95550.1 - 5.1e-22 78.1 1.0 0.011 16.1 0.0 9.5 7 2 2 9 9 9 5 HEAT repeats HEAT_EZ PF13513.6 KFQ95550.1 - 4.6e-21 74.9 7.1 0.00039 20.8 0.1 11.9 10 2 3 13 13 12 3 HEAT-like repeat HEAT PF02985.22 KFQ95550.1 - 2.2e-18 64.7 19.5 0.079 13.3 0.0 13.1 16 0 0 16 16 11 5 HEAT repeat UME PF08064.13 KFQ95550.1 - 1.9e-13 50.2 6.7 0.0083 16.0 0.1 8.1 6 2 1 8 8 8 2 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 KFQ95550.1 - 2.7e-09 37.5 5.7 0.0086 16.7 0.1 7.4 7 2 2 9 9 8 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KFQ95550.1 - 5.7e-09 35.9 2.9 0.095 12.3 0.0 6.2 6 1 1 7 7 7 2 CLASP N terminal Adaptin_N PF01602.20 KFQ95550.1 - 7.2e-09 34.7 14.0 0.00023 19.9 0.1 6.0 2 2 1 4 4 4 4 Adaptin N terminal region Telomere_reg-2 PF10193.9 KFQ95550.1 - 4.1e-08 33.6 6.1 0.49 10.8 0.0 6.8 7 0 0 7 7 5 1 Telomere length regulation protein Cnd1 PF12717.7 KFQ95550.1 - 7.1e-08 32.6 17.1 0.055 13.5 0.4 7.8 7 1 0 9 9 8 3 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 KFQ95550.1 - 4e-07 29.5 20.5 0.00021 20.6 0.6 7.3 6 2 2 8 8 8 2 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 KFQ95550.1 - 3.9e-06 27.0 10.2 1.1 9.4 0.1 7.8 8 1 1 9 9 8 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 PF11865.8 KFQ95550.1 - 0.00023 21.1 9.5 0.00076 19.4 0.1 5.7 7 2 0 7 7 6 1 Domain of unknown function (DUF3385) DRIM PF07539.12 KFQ95550.1 - 0.00033 19.1 9.0 0.17 10.1 0.2 5.1 3 1 3 6 6 6 2 Down-regulated in metastasis RIX1 PF08167.12 KFQ95550.1 - 0.00072 19.3 8.2 6.5 6.4 0.2 6.3 4 1 1 6 6 6 1 rRNA processing/ribosome biogenesis TAF6_C PF07571.13 KFQ95550.1 - 0.0053 17.0 0.1 3.6 8.0 0.0 4.6 3 2 0 3 3 3 1 TAF6 C-terminal HEAT repeat domain V-ATPase_H_N PF03224.14 KFQ95550.1 - 0.0065 15.8 5.8 1.6 8.0 0.3 4.7 3 1 2 5 5 5 1 V-ATPase subunit H VHS PF00790.19 KFQ95550.1 - 0.0065 16.3 0.5 1.8 8.4 0.1 4.1 3 0 0 3 3 3 1 VHS domain API5 PF05918.11 KFQ95550.1 - 0.0066 15.3 5.5 5 5.8 0.4 4.9 6 1 0 7 7 7 2 Apoptosis inhibitory protein 5 (API5) NUC173 PF08161.12 KFQ95550.1 - 0.008 15.9 1.9 14 5.2 0.0 5.3 5 2 1 6 6 6 0 NUC173 domain RRN3 PF05327.11 KFQ95550.1 - 0.023 13.2 0.5 0.075 11.6 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Uso1_p115_head PF04869.14 KFQ95550.1 - 0.036 13.2 0.1 0.27 10.3 0.1 2.5 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, head region Dopey_N PF04118.14 KFQ95550.1 - 0.05 12.7 2.0 5.6 6.0 0.1 3.6 2 1 1 3 3 3 0 Dopey, N-terminal GhoS PF11080.8 KFQ95550.1 - 0.16 11.9 0.0 0.66 10.0 0.0 2.0 1 0 0 1 1 1 0 Endoribonuclease GhoS V-ATPase_H_C PF11698.8 KFQ95550.1 - 0.2 11.8 9.0 26 5.0 0.1 6.2 7 1 0 8 8 7 0 V-ATPase subunit H RasGEF_N_2 PF14663.6 KFQ95550.1 - 0.5 10.8 2.8 40 4.7 0.1 4.5 4 0 0 4 4 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF4042 PF13251.6 KFQ95550.1 - 2 8.1 5.7 46 3.6 0.0 5.1 5 0 0 5 5 5 0 Domain of unknown function (DUF4042) PDZ PF00595.24 KFQ95551.1 - 5e-89 292.8 7.2 4.4e-14 52.6 0.0 7.3 7 0 0 7 7 7 7 PDZ domain PDZ_6 PF17820.1 KFQ95551.1 - 6e-67 221.4 4.9 1.3e-11 44.1 0.0 7.3 7 0 0 7 7 7 7 PDZ domain PDZ_2 PF13180.6 KFQ95551.1 - 7.8e-35 119.1 3.4 2e-05 24.8 0.0 7.5 7 0 0 7 7 7 7 PDZ domain Tricorn_PDZ PF14685.6 KFQ95551.1 - 7.4e-12 45.1 1.1 0.37 10.8 0.0 6.2 6 0 0 6 6 6 4 Tricorn protease PDZ domain GRASP55_65 PF04495.14 KFQ95551.1 - 0.00076 19.8 0.0 4.9 7.5 0.0 4.0 2 2 2 4 4 4 2 GRASP55/65 PDZ-like domain EutA PF06277.11 KFQ95551.1 - 0.085 11.7 1.5 0.47 9.2 0.1 2.4 3 0 0 3 3 3 0 Ethanolamine utilisation protein EutA FTH PF01827.27 KFQ95551.1 - 0.11 12.3 0.0 0.97 9.2 0.0 2.4 3 0 0 3 3 3 0 FTH domain AAA_30 PF13604.6 KFQ95552.1 - 4.1e-27 95.1 0.0 2.6e-26 92.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFQ95552.1 - 2.8e-15 56.9 0.0 2.3e-14 53.9 0.0 2.6 3 1 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 KFQ95552.1 - 1.1e-08 35.1 1.2 0.071 12.8 0.0 3.5 2 1 1 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 KFQ95552.1 - 4.9e-07 29.5 2.3 4.9e-07 29.5 2.3 1.8 2 0 0 2 2 1 1 UvrD-like helicase C-terminal domain CbiA PF01656.23 KFQ95552.1 - 0.00019 21.5 0.0 0.00039 20.5 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_11 PF13086.6 KFQ95552.1 - 0.00039 20.3 0.1 0.24 11.2 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 KFQ95552.1 - 0.00064 20.1 0.2 0.0021 18.5 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KFQ95552.1 - 0.0015 19.1 0.0 0.0079 16.7 0.0 2.3 2 0 0 2 2 1 1 ABC transporter ParA PF10609.9 KFQ95552.1 - 0.0041 16.6 0.0 0.0077 15.7 0.0 1.4 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase RsgA_GTPase PF03193.16 KFQ95552.1 - 0.0095 15.9 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 KFQ95552.1 - 0.0095 16.4 0.0 0.029 14.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 KFQ95552.1 - 0.02 14.6 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 KFQ95552.1 - 0.021 14.0 0.5 0.084 12.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.6 KFQ95552.1 - 0.041 13.6 0.4 0.1 12.4 0.0 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain DUF4888 PF16229.5 KFQ95552.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4888) ArsA_ATPase PF02374.15 KFQ95552.1 - 0.12 11.5 2.6 0.66 9.1 0.3 2.9 3 1 1 4 4 4 0 Anion-transporting ATPase AAA_18 PF13238.6 KFQ95552.1 - 0.14 12.7 0.2 0.64 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KFQ95552.1 - 0.14 11.9 0.4 2.8 7.7 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Rh5 PF18515.1 KFQ95552.1 - 0.39 10.0 3.9 6.3 6.0 0.7 2.8 2 1 1 3 3 3 0 Rh5 coiled-coil domain Yae1_N PF09811.9 KFQ95553.1 - 0.0066 16.1 26.7 0.012 15.3 14.1 4.1 3 1 0 3 3 3 1 Essential protein Yae1, N terminal Bax1-I PF01027.20 KFQ95554.1 - 1.3e-49 168.9 29.7 1.5e-49 168.7 29.7 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Vma12 PF11712.8 KFQ95554.1 - 0.037 14.1 1.0 0.037 14.1 1.0 2.4 2 1 1 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase 7TMR-DISM_7TM PF07695.11 KFQ95554.1 - 0.25 11.2 30.3 1.6 8.6 15.1 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling Laps PF10169.9 KFQ95555.1 - 1.3e-37 129.2 20.0 1.1e-36 126.2 20.0 1.9 1 1 0 1 1 1 1 Learning-associated protein DUF2423 PF10338.9 KFQ95555.1 - 7.3e-05 22.9 7.9 7.3e-05 22.9 7.9 2.6 3 1 0 3 3 3 1 Protein of unknown function (DUF2423) AT_hook PF02178.19 KFQ95556.1 - 0.0085 15.9 27.1 0.079 12.9 7.2 3.2 3 1 0 3 3 3 2 AT hook motif SelR PF01641.18 KFQ95557.1 - 4e-54 181.9 0.2 5e-54 181.5 0.2 1.1 1 0 0 1 1 1 1 SelR domain zf-ribbon_3 PF13248.6 KFQ95557.1 - 0.0048 16.3 1.0 0.49 9.9 0.1 2.8 2 0 0 2 2 2 1 zinc-ribbon domain Yippee-Mis18 PF03226.14 KFQ95557.1 - 0.025 14.8 0.1 0.07 13.3 0.1 1.8 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn_ribbon_SprT PF17283.2 KFQ95557.1 - 0.034 14.1 0.7 0.45 10.5 0.8 2.5 1 1 0 1 1 1 0 SprT-like zinc ribbon domain DZR PF12773.7 KFQ95557.1 - 0.039 14.0 0.4 0.37 10.8 0.4 2.4 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_10 PF10058.9 KFQ95557.1 - 0.042 13.6 0.8 0.98 9.2 0.1 2.4 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-Mss51 PF13824.6 KFQ95557.1 - 0.058 13.5 3.2 0.21 11.7 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 GFA PF04828.14 KFQ95557.1 - 0.13 12.7 1.7 1.6 9.2 0.4 2.4 2 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_2 PF13240.6 KFQ95557.1 - 0.68 9.7 4.1 8 6.3 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zf-tcix PF14952.6 KFQ95557.1 - 1.1 8.9 6.5 25 4.6 0.2 3.3 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding MSC PF09402.10 KFQ95558.1 - 1.7e-20 73.8 0.8 2.7e-20 73.1 0.8 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain RBM39linker PF15519.6 KFQ95558.1 - 0.0037 18.3 1.6 0.009 17.1 0.0 2.5 3 0 0 3 3 3 1 linker between RRM2 and RRM3 domains in RBM39 protein EGF_2 PF07974.13 KFQ95559.1 - 1.6e-19 69.9 92.2 0.00031 21.1 5.1 5.3 5 0 0 5 5 5 5 EGF-like domain WIF PF02019.18 KFQ95559.1 - 5.2e-15 55.3 0.0 7.2e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 WIF domain hEGF PF12661.7 KFQ95559.1 - 1.7e-12 47.4 65.6 0.00039 20.9 6.5 6.3 5 1 0 5 5 5 5 Human growth factor-like EGF EGF PF00008.27 KFQ95559.1 - 3e-11 43.4 88.2 0.00036 20.7 8.6 5.6 5 0 0 5 5 5 4 EGF-like domain DSL PF01414.19 KFQ95559.1 - 0.038 14.3 9.0 0.038 14.3 9.0 3.9 2 2 1 3 3 3 0 Delta serrate ligand Laminin_EGF PF00053.24 KFQ95559.1 - 2.1 8.6 72.1 4.3 7.6 9.3 5.3 1 1 4 5 5 5 0 Laminin EGF domain DUF4682 PF15733.5 KFQ95560.1 - 1.5e-43 148.4 3.1 1.5e-43 148.4 3.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4682) RabGAP-TBC PF00566.18 KFQ95560.1 - 1.5e-36 126.1 1.2 2e-36 125.7 0.1 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain 60KD_IMP PF02096.20 KFQ95560.1 - 0.02 14.8 0.4 0.02 14.8 0.4 2.7 3 0 0 3 3 3 0 60Kd inner membrane protein Sulfatase PF00884.23 KFQ95561.1 - 1.1e-64 218.8 0.5 1.4e-64 218.5 0.5 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFQ95561.1 - 2.4e-07 30.7 0.1 0.0023 17.6 0.1 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KFQ95561.1 - 1.4e-05 25.2 0.1 0.23 11.7 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4976) DUF229 PF02995.17 KFQ95561.1 - 0.019 13.6 0.0 0.056 12.1 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF229) RA PF00788.23 KFQ95562.1 - 3.6e-22 78.8 0.1 3.4e-21 75.7 0.1 2.1 1 1 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Nore1-SARAH PF16517.5 KFQ95562.1 - 4e-16 58.6 3.4 4e-16 58.6 3.4 1.8 2 0 0 2 2 2 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Ras_bdg_2 PF14847.6 KFQ95562.1 - 0.013 15.8 0.0 0.024 15.0 0.0 1.6 1 1 0 1 1 1 0 Ras-binding domain of Byr2 Mst1_SARAH PF11629.8 KFQ95562.1 - 0.022 14.8 0.8 0.046 13.8 0.8 1.5 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 C1_1 PF00130.22 KFQ95563.1 - 0.076 12.9 5.4 0.11 12.4 5.4 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TBK1_CCD1 PF18394.1 KFQ95564.1 - 4e-122 406.7 4.8 6.3e-122 406.0 4.8 1.3 1 0 0 1 1 1 1 TANK-binding kinase 1 coiled-coil domain 1 Pkinase PF00069.25 KFQ95564.1 - 1.3e-45 155.8 0.0 2.8e-45 154.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain TBK1_ULD PF18396.1 KFQ95564.1 - 2.3e-37 126.8 4.5 4.1e-37 126.0 1.8 2.5 2 0 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain Pkinase_Tyr PF07714.17 KFQ95564.1 - 6.7e-26 91.1 0.0 1.3e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFQ95564.1 - 9.8e-07 27.9 0.0 4.7e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KFQ95564.1 - 0.00011 21.6 0.0 0.0016 17.8 0.0 2.3 2 0 0 2 2 2 1 Kinase-like ubiquitin PF00240.23 KFQ95564.1 - 0.0022 17.7 0.4 0.0062 16.3 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin family NPV_P10 PF05531.12 KFQ95564.1 - 0.0029 18.0 0.2 0.95 10.0 0.1 2.7 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein RIO1 PF01163.22 KFQ95564.1 - 0.0051 16.4 0.1 0.2 11.3 0.1 2.5 1 1 1 2 2 2 1 RIO1 family Xpo1 PF08389.12 KFQ95565.1 - 3.6e-37 127.7 10.9 8.9e-37 126.4 1.3 4.2 4 1 0 4 4 4 2 Exportin 1-like protein HEAT PF02985.22 KFQ95565.1 - 0.044 14.1 0.4 14 6.3 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat Csm2_III-A PF03750.13 KFQ95565.1 - 0.34 11.8 3.6 2.6 8.9 0.0 3.8 4 1 0 4 4 4 0 Csm2 Type III-A Phage_min_cap2 PF06152.11 KFQ95565.1 - 0.34 9.8 2.2 0.49 9.2 0.5 1.9 2 0 0 2 2 2 0 Phage minor capsid protein 2 Ribosomal_L18A PF01775.17 KFQ95566.1 - 1.1e-56 190.1 0.0 1.4e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A C12orf66_like PF09404.10 KFQ95568.1 - 2.1e-247 821.1 9.0 2.6e-247 820.8 9.0 1.0 1 0 0 1 1 1 1 KICSTOR complex C12orf66 like Urb2 PF10441.9 KFQ95568.1 - 0.038 13.9 0.7 0.081 12.8 0.4 1.6 1 1 0 1 1 1 0 Urb2/Npa2 family RNase_3_N PF18497.1 KFQ95568.1 - 0.058 13.6 1.3 1.2 9.4 0.1 2.7 2 1 0 2 2 2 0 Ribonuclease III N-terminal domain Pox_I1 PF03289.13 KFQ95568.1 - 0.12 11.5 0.5 0.78 8.8 0.1 2.1 2 0 0 2 2 2 0 Poxvirus protein I1 RhoGAP PF00620.27 KFQ95569.1 - 1.2e-46 158.3 0.4 1.3e-45 155.0 0.0 2.7 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 KFQ95569.1 - 3.6e-17 62.4 6.5 8.3e-17 61.2 5.3 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KFQ95569.1 - 4.9e-10 38.8 0.0 9.2e-10 38.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFQ95569.1 - 7.8e-10 38.5 0.0 1.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFQ95569.1 - 1.1e-08 34.7 0.0 2.3e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DASH_Dad3 PF08656.10 KFQ95569.1 - 0.37 10.9 3.3 12 6.1 1.4 3.1 2 0 0 2 2 2 0 DASH complex subunit Dad3 FlaC_arch PF05377.11 KFQ95569.1 - 0.58 10.6 6.1 0.2 12.1 1.1 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) IF-2B PF01008.17 KFQ95570.1 - 2.4e-87 292.7 0.0 6.4e-87 291.3 0.0 1.6 2 0 0 2 2 2 1 Initiation factor 2 subunit family DUF3450 PF11932.8 KFQ95570.1 - 0.017 14.4 2.5 0.035 13.4 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SNX17_FERM_C PF18116.1 KFQ95571.1 - 4e-41 139.4 0.1 2e-40 137.2 0.0 2.1 2 0 0 2 2 2 1 Sorting Nexin 17 FERM C-terminal domain PX PF00787.24 KFQ95571.1 - 6.2e-15 55.2 0.2 2.1e-14 53.5 0.1 1.9 2 0 0 2 2 2 1 PX domain FERM_M PF00373.18 KFQ95571.1 - 0.0079 16.6 0.7 0.083 13.3 0.3 2.6 2 1 1 3 3 3 1 FERM central domain RA PF00788.23 KFQ95571.1 - 0.024 15.3 0.1 0.057 14.0 0.1 1.7 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Nif11 PF07862.11 KFQ95571.1 - 0.039 14.3 0.3 3.8 7.9 0.0 3.0 3 0 0 3 3 3 0 Nif11 domain Ras_bdg_2 PF14847.6 KFQ95571.1 - 0.085 13.2 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Ras-binding domain of Byr2 FERM_N PF09379.10 KFQ95571.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 FERM N-terminal domain Med15_fungi PF05397.12 KFQ95571.1 - 0.4 11.0 3.3 0.65 10.3 0.0 2.6 3 0 0 3 3 3 0 Mediator complex subunit 15 zf-H2C2_2 PF13465.6 KFQ95572.1 - 6.2e-43 143.4 66.6 7.4e-10 38.8 1.7 9.9 10 0 0 10 10 10 6 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFQ95572.1 - 2.3e-39 132.7 50.1 1.9e-06 27.5 0.0 7.2 7 0 0 7 7 7 7 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFQ95572.1 - 1.6e-19 69.2 68.9 0.0018 18.7 0.4 8.5 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ95572.1 - 1.2e-12 47.5 61.1 0.054 14.4 3.2 8.4 8 0 0 8 8 8 6 C2H2-type zinc finger GAGA PF09237.11 KFQ95572.1 - 1.3e-05 24.9 25.1 0.059 13.2 0.5 5.6 3 2 3 6 6 6 3 GAGA factor zf-C2HE PF16278.5 KFQ95572.1 - 3.3e-05 24.3 41.9 0.039 14.4 1.9 6.6 3 2 5 8 8 8 4 C2HE / C2H2 / C2HC zinc-binding finger OrsD PF12013.8 KFQ95572.1 - 0.065 13.7 41.8 8.5 6.9 0.3 7.8 5 2 3 8 8 8 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf_C2H2_10 PF18414.1 KFQ95572.1 - 1 9.0 10.1 4.4 6.9 0.7 3.6 3 0 0 3 3 3 0 C2H2 type zinc-finger AKAP95 PF04988.12 KFQ95572.1 - 2.8 8.2 23.8 1.8 8.8 0.3 5.4 6 1 0 6 6 6 0 A-kinase anchoring protein 95 (AKAP95) IBR PF01485.21 KFQ95575.1 - 8e-20 70.8 34.3 1.7e-14 53.8 5.8 3.9 3 1 2 5 5 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KFQ95575.1 - 0.00072 19.4 6.7 0.00072 19.4 6.7 4.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ95575.1 - 0.0029 17.9 7.6 0.0029 17.9 7.6 4.5 4 2 1 5 5 5 1 Ring finger domain zf-RING_5 PF14634.6 KFQ95575.1 - 0.0031 17.4 5.4 0.0031 17.4 5.4 4.5 4 1 1 5 5 5 1 zinc-RING finger domain PP2C PF00481.21 KFQ95576.1 - 1.3e-68 231.5 1.1 4.1e-57 193.8 0.4 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KFQ95576.1 - 0.0055 16.4 0.0 0.03 14.0 0.0 2.1 2 1 0 2 2 2 1 Protein phosphatase 2C DUF4481 PF14800.6 KFQ95576.1 - 1.7 8.1 3.0 2 7.8 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4481) Pkinase_Tyr PF07714.17 KFQ95577.1 - 1.4e-24 86.8 0.5 2.9e-24 85.8 0.5 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ95577.1 - 1.5e-24 86.8 1.6 3.9e-24 85.4 1.6 1.6 1 1 0 1 1 1 1 Protein kinase domain PRESAN PF09687.10 KFQ95577.1 - 0.11 13.1 7.3 0.35 11.4 6.9 2.1 2 0 0 2 2 2 0 Plasmodium RESA N-terminal BCLP PF12304.8 KFQ95578.1 - 1.6e-36 125.6 1.5 1.7e-36 125.5 1.5 1.0 1 0 0 1 1 1 1 Beta-casein like protein Clathrin PF00637.20 KFQ95579.1 - 1e-10 41.7 32.9 0.039 13.8 0.3 10.1 6 3 4 11 11 11 6 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 KFQ95579.1 - 9.2e-10 38.7 0.1 0.0048 17.2 0.0 5.2 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFQ95579.1 - 2.2e-06 28.2 5.7 1.2 10.1 0.1 6.6 7 0 0 7 7 7 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KFQ95579.1 - 0.0013 17.9 0.1 0.0013 17.9 0.1 5.4 3 2 2 6 6 6 1 Coatomer WD associated region TPR_7 PF13176.6 KFQ95579.1 - 0.03 14.4 32.4 18 5.7 0.0 11.7 11 3 1 12 12 12 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ95579.1 - 0.037 14.1 58.1 2 8.7 0.4 13.5 13 1 1 14 14 14 0 Tetratricopeptide repeat fn1 PF00039.18 KFQ95579.1 - 0.093 12.9 4.1 22 5.3 0.0 4.7 5 0 0 5 5 5 0 Fibronectin type I domain TPR_12 PF13424.6 KFQ95579.1 - 0.46 10.8 44.6 7.4 6.9 0.5 12.0 12 3 1 13 13 13 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KFQ95579.1 - 1.2 9.2 18.9 2.7 8.0 0.2 6.3 7 1 1 8 8 8 0 Mad3/BUB1 homology region 1 PID PF00640.23 KFQ95580.1 - 1.8e-19 70.2 0.1 2.3e-19 69.8 0.1 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID_2 PF14719.6 KFQ95580.1 - 1.6e-13 51.0 0.1 1.9e-13 50.7 0.1 1.0 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFQ95580.1 - 1.6e-10 41.3 0.0 2e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosine-binding domain fn3 PF00041.21 KFQ95581.1 - 4.8e-10 39.7 0.1 4.8e-10 39.7 0.1 1.9 3 0 0 3 3 3 1 Fibronectin type III domain DUF4808 PF16066.5 KFQ95581.1 - 0.00019 22.0 0.0 0.00036 21.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4808) Pur_ac_phosph_N PF16656.5 KFQ95581.1 - 0.0039 17.7 0.2 0.012 16.1 0.2 1.8 1 1 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain DUF4992 PF16383.5 KFQ95581.1 - 0.017 14.7 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function zf-C2H2_4 PF13894.6 KFQ95583.1 - 7.8e-10 38.7 37.5 0.017 15.9 3.5 6.5 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KFQ95583.1 - 4.3e-08 33.2 30.2 0.0014 19.0 3.5 6.4 6 0 0 6 6 6 3 Zinc finger, C2H2 type IBR PF01485.21 KFQ95583.1 - 2.1e-06 27.9 17.6 0.057 13.7 1.6 3.7 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain zf-BED PF02892.15 KFQ95583.1 - 2.7e-06 27.3 27.8 0.038 14.0 4.9 5.5 4 1 1 5 5 5 4 BED zinc finger CpXC PF14353.6 KFQ95583.1 - 4.8e-06 26.6 10.2 0.0028 17.7 0.1 3.7 3 1 0 3 3 3 2 CpXC protein zf-C2H2_jaz PF12171.8 KFQ95583.1 - 1.7e-05 24.9 17.4 0.0015 18.8 1.2 4.0 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-FCS PF06467.14 KFQ95583.1 - 0.00027 20.8 3.1 0.078 12.9 0.1 3.3 3 0 0 3 3 3 2 MYM-type Zinc finger with FCS sequence motif zf-C2H2_3rep PF18868.1 KFQ95583.1 - 0.015 15.9 11.5 0.67 10.6 0.0 3.9 3 1 2 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_aberr PF17017.5 KFQ95583.1 - 0.018 15.2 20.8 0.59 10.2 0.5 4.5 3 2 1 4 4 4 0 Aberrant zinc-finger zf-C2H2_2 PF12756.7 KFQ95583.1 - 0.054 13.8 25.7 0.33 11.3 0.1 5.0 3 3 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 KFQ95583.1 - 0.15 12.5 26.1 11 6.5 6.0 6.1 5 2 0 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_12 PF18658.1 KFQ95583.1 - 3.7 7.2 12.8 9.8 5.8 0.0 4.1 4 1 1 5 5 5 0 Zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KFQ95583.1 - 6 7.1 19.3 10 6.4 0.9 5.0 5 0 0 5 5 5 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 KFQ95583.1 - 9.4 6.1 14.4 7 6.5 0.7 3.9 4 0 0 4 4 4 0 zinc-ribbon domain zf-met PF12874.7 KFQ95583.1 - 9.4 6.8 20.7 0.47 10.9 0.3 4.6 5 0 0 5 5 5 0 Zinc-finger of C2H2 type ATP_bind_1 PF03029.17 KFQ95584.1 - 1.2e-80 270.8 0.3 1.9e-80 270.1 0.1 1.5 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KFQ95584.1 - 3.6e-08 33.2 0.2 4.3e-06 26.4 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 KFQ95584.1 - 6.8e-06 25.8 0.0 0.07 12.7 0.0 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KFQ95584.1 - 9.7e-06 25.8 0.0 3.4e-05 24.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.23 KFQ95584.1 - 1.5e-05 25.1 0.0 0.00033 20.7 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFQ95584.1 - 1.9e-05 24.2 0.2 0.00013 21.5 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 KFQ95584.1 - 2.7e-05 24.6 0.1 8e-05 23.1 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KFQ95584.1 - 0.00018 21.5 0.1 0.00049 20.0 0.0 1.8 2 0 0 2 2 1 1 NACHT domain SRP54 PF00448.22 KFQ95584.1 - 0.00029 20.5 0.0 0.0053 16.4 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Arf PF00025.21 KFQ95584.1 - 0.00035 20.1 0.0 0.45 9.9 0.0 2.9 2 1 0 2 2 2 1 ADP-ribosylation factor family CLP1_P PF16575.5 KFQ95584.1 - 0.00035 20.4 0.0 0.019 14.8 0.0 2.6 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_24 PF13479.6 KFQ95584.1 - 0.00094 19.0 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KFQ95584.1 - 0.00098 19.1 0.0 0.27 11.1 0.0 2.3 2 0 0 2 2 2 1 NTPase AAA_18 PF13238.6 KFQ95584.1 - 0.0012 19.4 0.0 0.0061 17.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 KFQ95584.1 - 0.0023 17.2 0.1 0.52 9.4 0.0 2.6 2 1 0 2 2 2 1 G-protein alpha subunit SRPRB PF09439.10 KFQ95584.1 - 0.0031 17.0 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KFQ95584.1 - 0.0031 17.8 0.0 0.062 13.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFQ95584.1 - 0.0047 16.9 0.0 0.015 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 KFQ95584.1 - 0.0048 16.8 0.5 6.3 6.7 0.0 3.5 3 1 0 3 3 2 0 RsgA GTPase Viral_helicase1 PF01443.18 KFQ95584.1 - 0.006 16.3 0.0 0.019 14.7 0.0 1.9 3 0 0 3 3 1 1 Viral (Superfamily 1) RNA helicase MeaB PF03308.16 KFQ95584.1 - 0.009 15.0 0.1 0.78 8.7 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 KFQ95584.1 - 0.013 15.5 0.0 0.1 12.6 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 KFQ95584.1 - 0.013 15.7 0.0 3.1 8.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 KFQ95584.1 - 0.014 15.5 0.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 KFQ95584.1 - 0.019 15.5 0.2 0.16 12.5 0.0 2.2 2 1 0 2 2 1 0 AAA domain AAA_19 PF13245.6 KFQ95584.1 - 0.025 14.9 0.1 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KFQ95584.1 - 0.029 14.1 0.3 1 9.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 KFQ95584.1 - 0.041 14.1 0.1 0.38 11.0 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KFQ95584.1 - 0.042 13.4 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 KFQ95584.1 - 0.047 13.7 0.2 1.2 9.2 0.0 3.0 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KFQ95584.1 - 0.052 12.8 0.0 0.15 11.3 0.0 1.8 1 1 0 1 1 1 0 KAP family P-loop domain AAA_30 PF13604.6 KFQ95584.1 - 0.053 13.2 0.8 0.18 11.5 0.8 1.8 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KFQ95584.1 - 0.074 12.2 0.0 0.21 10.8 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain UvrD-helicase PF00580.21 KFQ95584.1 - 0.086 12.3 0.0 5.7 6.4 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_31 PF13614.6 KFQ95584.1 - 0.098 12.6 0.0 13 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFQ95584.1 - 0.12 12.8 0.0 0.86 10.0 0.0 2.5 2 1 0 2 2 2 0 RNA helicase Dynamin_N PF00350.23 KFQ95584.1 - 0.19 11.8 3.9 4.2 7.4 0.0 3.5 4 1 1 5 5 5 0 Dynamin family Thymidylate_kin PF02223.17 KFQ95584.1 - 0.28 10.8 0.0 0.28 10.8 0.0 2.3 4 0 0 4 4 2 0 Thymidylate kinase Zeta_toxin PF06414.12 KFQ95584.1 - 0.34 10.1 2.4 0.75 9.0 0.0 2.6 2 1 1 3 3 3 0 Zeta toxin AAA_17 PF13207.6 KFQ95584.1 - 0.48 10.9 2.4 0.99 9.8 0.0 2.7 3 1 1 4 4 3 0 AAA domain DUF4398 PF14346.6 KFQ95584.1 - 0.51 11.0 2.7 6.8 7.4 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) Ets PF00178.22 KFQ95585.1 - 7.8e-31 106.4 1.4 1.4e-30 105.6 1.4 1.4 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 KFQ95585.1 - 8.7e-18 64.1 0.0 3.3e-17 62.2 0.0 2.0 3 0 0 3 3 3 1 Sterile alpha motif (SAM)/Pointed domain AT_hook PF02178.19 KFQ95585.1 - 0.16 11.9 5.1 0.38 10.8 5.1 1.7 1 0 0 1 1 1 0 AT hook motif HTH_32 PF13565.6 KFQ95585.1 - 0.43 11.2 2.0 8.2 7.1 2.2 2.6 2 1 0 2 2 2 0 Homeodomain-like domain 7tm_1 PF00001.21 KFQ95586.1 - 3.7e-22 78.9 17.6 5.5e-22 78.3 17.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) COX7C PF02935.16 KFQ95586.1 - 0.14 12.5 1.2 18 5.7 0.0 2.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc PDR_CDR PF06422.12 KFQ95586.1 - 0.26 11.2 3.8 2.6 8.0 0.1 2.7 2 0 0 2 2 2 0 CDR ABC transporter Arf PF00025.21 KFQ95587.1 - 2.5e-39 134.5 0.0 3e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFQ95587.1 - 6.9e-14 51.8 0.0 7.6e-14 51.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ95587.1 - 7.7e-11 42.3 0.0 1.2e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KFQ95587.1 - 2.3e-06 27.1 0.0 2.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KFQ95587.1 - 1.9e-05 24.0 0.0 2.3e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.23 KFQ95587.1 - 0.0011 19.1 0.0 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFQ95587.1 - 0.0028 17.1 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Y_phosphatase PF00102.27 KFQ95588.1 - 3.9e-71 239.3 0.0 4.9e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFQ95588.1 - 4.1e-05 23.4 0.0 9.2e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFQ95588.1 - 0.0022 18.0 0.0 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family LRR_8 PF13855.6 KFQ95589.1 - 7.8e-68 224.1 40.4 3.1e-16 58.9 0.4 7.2 3 2 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 KFQ95589.1 - 1.3e-35 120.8 21.4 6.7e-06 26.4 0.7 8.7 5 1 5 10 10 10 10 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFQ95589.1 - 3.5e-19 69.0 0.0 1.1e-07 31.8 0.0 3.5 1 1 0 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFQ95589.1 - 1e-13 51.2 7.8 0.00021 20.9 0.1 4.5 1 1 4 5 5 5 5 Leucine-rich repeat LRR_1 PF00560.33 KFQ95589.1 - 1.5e-07 31.0 26.6 4.9 8.1 0.2 10.6 10 2 0 10 10 10 4 Leucine Rich Repeat 7tm_1 PF00001.21 KFQ95589.1 - 2.3e-07 30.4 16.6 5.5e-07 29.2 16.6 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_6 PF13516.6 KFQ95589.1 - 0.046 13.8 30.7 0.55 10.4 0.1 8.4 10 0 0 10 10 10 0 Leucine Rich repeat RVT_1 PF00078.27 KFQ95590.1 - 0.0061 16.1 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Kelch_1 PF01344.25 KFQ95591.1 - 6.9e-80 262.4 18.5 1.2e-14 53.5 0.2 6.9 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 KFQ95591.1 - 1.3e-44 149.1 13.3 4.9e-10 39.3 0.0 6.3 2 2 4 6 6 6 6 Kelch motif BACK PF07707.15 KFQ95591.1 - 1.4e-34 118.3 0.8 2.9e-34 117.2 0.8 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 KFQ95591.1 - 1e-31 109.4 1.0 2.3e-31 108.3 1.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 KFQ95591.1 - 1.3e-29 101.0 4.3 8e-05 22.5 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KFQ95591.1 - 3.4e-27 94.2 11.4 1.6e-07 31.4 0.7 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.6 KFQ95591.1 - 1.9e-24 85.4 9.8 0.00045 20.2 0.0 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 KFQ95591.1 - 6.7e-13 48.3 10.3 0.023 14.7 0.1 6.1 6 0 0 6 6 6 4 Kelch motif Glu_cyclase_2 PF05096.12 KFQ95591.1 - 0.13 11.6 0.0 0.48 9.8 0.0 1.9 1 1 0 1 1 1 0 Glutamine cyclotransferase Tubulin PF00091.25 KFQ95592.1 - 4e-68 229.5 0.0 5.4e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFQ95592.1 - 5e-48 162.4 0.0 8.5e-48 161.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFQ95592.1 - 0.0054 16.4 0.0 0.0087 15.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain NUDIX_5 PF16705.5 KFQ95592.1 - 0.084 12.6 0.0 5.5 6.7 0.0 2.3 2 0 0 2 2 2 0 NUDIX, or N-terminal NPxY motif-rich, region of KRIT PLU-1 PF08429.11 KFQ95593.1 - 8.2e-93 311.2 11.8 2.6e-89 299.8 4.1 4.0 4 0 0 4 4 4 3 PLU-1-like protein JmjC PF02373.22 KFQ95593.1 - 7.1e-45 152.1 0.7 1.6e-44 150.9 0.7 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 KFQ95593.1 - 6.8e-25 86.7 38.1 1.1e-11 44.4 4.1 4.2 4 0 0 4 4 4 3 PHD-finger ARID PF01388.21 KFQ95593.1 - 1.2e-17 64.3 0.0 3e-17 63.0 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.16 KFQ95593.1 - 2e-13 50.5 12.1 2e-13 50.5 12.1 3.7 3 0 0 3 3 3 1 C5HC2 zinc finger PHD_2 PF13831.6 KFQ95593.1 - 0.02 14.4 27.9 0.18 11.4 2.2 4.0 4 0 0 4 4 4 0 PHD-finger Zf_RING PF16744.5 KFQ95593.1 - 7.1 6.8 12.1 1.7 8.8 1.2 3.5 3 0 0 3 3 3 0 KIAA1045 RING finger zf-PHD-like PF15446.6 KFQ95593.1 - 7.4 6.2 18.4 0.19 11.4 0.4 4.4 5 0 0 5 5 5 0 PHD/FYVE-zinc-finger like domain IBN_N PF03810.19 KFQ95594.1 - 5e-06 26.3 0.0 2e-05 24.4 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KFQ95594.1 - 1.2e-05 25.4 1.8 0.0015 18.6 0.0 4.1 4 0 0 4 4 4 1 Exportin 1-like protein Cse1 PF08506.10 KFQ95594.1 - 0.00013 21.0 0.2 0.003 16.5 0.1 2.4 2 0 0 2 2 2 1 Cse1 RIX1 PF08167.12 KFQ95594.1 - 0.013 15.2 8.0 2.8 7.6 0.1 4.8 6 0 0 6 6 6 0 rRNA processing/ribosome biogenesis MutL_C PF08676.11 KFQ95594.1 - 0.05 13.4 0.3 0.48 10.2 0.0 2.7 3 0 0 3 3 3 0 MutL C terminal dimerisation domain UNC45-central PF11701.8 KFQ95594.1 - 0.1 12.6 0.3 2.1 8.3 0.1 3.1 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central Kelch_3 PF13415.6 KFQ95595.1 - 1.6e-40 136.7 2.0 9.7e-06 25.7 0.1 8.1 8 0 0 8 8 8 7 Galactose oxidase, central domain Kelch_4 PF13418.6 KFQ95595.1 - 3.9e-35 119.6 6.6 1.3e-08 34.7 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain BTB PF00651.31 KFQ95595.1 - 1.5e-33 115.3 5.8 5.6e-21 74.8 0.0 4.9 2 2 2 4 4 4 3 BTB/POZ domain Kelch_1 PF01344.25 KFQ95595.1 - 5.9e-32 109.0 5.2 1.9e-08 33.7 0.0 5.9 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 KFQ95595.1 - 1.3e-29 101.7 4.7 4.6e-07 29.7 0.3 5.5 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 KFQ95595.1 - 2e-26 91.4 9.4 4.3e-09 36.3 0.0 6.4 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KFQ95595.1 - 1.7e-19 69.0 1.5 1.8e-06 27.7 0.0 5.4 5 0 0 5 5 5 3 Kelch motif RAG2 PF03089.14 KFQ95595.1 - 9.2e-05 21.6 0.0 0.00074 18.6 0.0 2.2 2 0 0 2 2 2 1 Recombination activating protein 2 BACK PF07707.15 KFQ95595.1 - 0.0026 17.8 12.5 0.0059 16.7 1.1 4.6 5 0 0 5 5 5 1 BTB And C-terminal Kelch Peptidase_M1 PF01433.20 KFQ95596.1 - 8.3e-50 169.4 0.0 1.3e-49 168.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KFQ95596.1 - 6e-14 52.7 1.4 1.1e-13 51.8 1.4 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Leuk-A4-hydro_C PF09127.11 KFQ95596.1 - 3.3e-09 36.8 0.1 6e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.6 KFQ95596.1 - 0.034 13.8 0.1 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Peptidase MA superfamily AAA_16 PF13191.6 KFQ95597.1 - 0.0011 19.4 2.7 0.0016 18.9 0.0 2.4 2 1 1 3 3 2 1 AAA ATPase domain AAA PF00004.29 KFQ95597.1 - 0.0021 18.5 0.0 0.0066 16.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFQ95597.1 - 0.0024 18.1 0.0 0.009 16.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFQ95597.1 - 0.0044 16.8 0.0 0.0082 15.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 KFQ95597.1 - 0.0048 17.2 0.2 0.012 15.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.6 KFQ95597.1 - 0.0081 16.5 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KFQ95597.1 - 0.0089 15.1 0.0 0.02 14.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ATG16 PF08614.11 KFQ95597.1 - 0.0092 16.2 7.4 0.0092 16.2 7.4 3.2 3 0 0 3 3 2 1 Autophagy protein 16 (ATG16) PhoH PF02562.16 KFQ95597.1 - 0.0093 15.4 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_5 PF07728.14 KFQ95597.1 - 0.018 15.0 0.0 0.046 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KFQ95597.1 - 0.019 15.3 0.0 0.046 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KFQ95597.1 - 0.021 14.9 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KFQ95597.1 - 0.032 13.6 0.0 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 KFQ95597.1 - 0.045 13.7 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 KFQ95597.1 - 0.071 12.8 0.2 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KFQ95597.1 - 0.087 13.4 0.0 0.28 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 KFQ95597.1 - 0.089 12.9 0.0 0.27 11.3 0.0 1.8 2 0 0 2 2 1 0 Torsin NACHT PF05729.12 KFQ95597.1 - 0.1 12.5 0.0 0.38 10.7 0.0 2.0 2 0 0 2 2 1 0 NACHT domain AAA_7 PF12775.7 KFQ95597.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region CwsA PF10814.8 KFQ95597.1 - 0.13 12.4 3.3 0.24 11.6 0.5 2.7 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA Exonuc_VII_L PF02601.15 KFQ95597.1 - 0.14 11.7 5.7 0.19 11.3 2.8 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Rx_N PF18052.1 KFQ95597.1 - 0.64 10.3 2.9 21 5.5 0.2 3.3 3 0 0 3 3 3 0 Rx N-terminal domain DUF4407 PF14362.6 KFQ95597.1 - 0.92 8.8 3.6 2 7.7 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4763 PF15960.5 KFQ95597.1 - 4.1 6.6 11.6 2.3 7.4 1.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) UPF0242 PF06785.11 KFQ95597.1 - 6.1 6.9 15.3 3.5 7.7 4.5 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HOOK PF05622.12 KFQ95597.1 - 6.3 4.8 19.4 0.98 7.5 1.1 2.7 3 0 0 3 3 3 0 HOOK protein DUF4201 PF13870.6 KFQ95597.1 - 6.9 6.4 19.8 0.98 9.1 5.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) C2 PF00168.30 KFQ95598.1 - 2.7e-55 185.0 0.2 1.5e-28 99.1 0.0 2.3 2 0 0 2 2 2 2 C2 domain MAP17 PF15807.5 KFQ95598.1 - 1.6e-05 25.2 0.1 3.9e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 CEP76-C2 PF15627.6 KFQ95598.1 - 2.8e-05 23.7 0.0 0.098 12.2 0.0 2.4 1 1 1 2 2 2 2 CEP76 C2 domain DOCK-C2 PF14429.6 KFQ95598.1 - 0.00071 19.4 0.0 0.79 9.5 0.0 2.4 2 0 0 2 2 2 2 C2 domain in Dock180 and Zizimin proteins PI3K_C2 PF00792.24 KFQ95598.1 - 0.00079 19.4 0.0 0.5 10.3 0.0 2.7 2 0 0 2 2 2 2 Phosphoinositide 3-kinase C2 TMEM52 PF14979.6 KFQ95598.1 - 0.0012 18.8 2.6 0.0023 17.9 2.6 1.4 1 0 0 1 1 1 1 Transmembrane 52 FAM176 PF14851.6 KFQ95598.1 - 0.0056 16.3 0.5 0.011 15.5 0.5 1.4 1 0 0 1 1 1 1 FAM176 family EphA2_TM PF14575.6 KFQ95598.1 - 0.0082 17.0 0.0 0.02 15.8 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Comm PF15957.5 KFQ95598.1 - 0.017 15.4 0.0 0.038 14.3 0.0 1.5 1 0 0 1 1 1 0 Commissureless Transglut_C PF00927.22 KFQ95598.1 - 0.039 14.1 0.8 6.9 6.9 0.1 2.4 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain PRKG1_interact PF15898.5 KFQ95599.1 - 4.3e-35 120.7 21.4 4.3e-35 120.7 21.4 6.2 6 3 0 6 6 6 1 cGMP-dependent protein kinase interacting domain Ank_4 PF13637.6 KFQ95599.1 - 1.1e-27 96.0 0.7 6.2e-13 49.0 0.0 3.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFQ95599.1 - 1.7e-25 89.4 0.3 1.1e-12 48.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFQ95599.1 - 6.8e-24 83.6 1.5 2.3e-09 37.3 0.0 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KFQ95599.1 - 1e-20 73.1 4.6 3.8e-06 27.1 0.1 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KFQ95599.1 - 1.2e-17 62.2 1.8 0.00059 20.1 0.1 5.0 5 0 0 5 5 5 4 Ankyrin repeat LIM PF00412.22 KFQ95600.1 - 5.8e-30 103.3 24.8 5.1e-17 61.8 5.1 2.1 2 0 0 2 2 2 2 LIM domain zf_UBZ PF18439.1 KFQ95600.1 - 0.033 13.8 9.8 1.1 8.9 0.3 4.0 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-ACC PF17848.1 KFQ95600.1 - 0.41 10.8 0.2 0.41 10.8 0.2 4.9 6 0 0 6 6 6 0 Acetyl-coA carboxylase zinc finger domain DUF4428 PF14471.6 KFQ95600.1 - 3 7.8 16.1 0.59 10.1 1.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) Zn-ribbon_8 PF09723.10 KFQ95600.1 - 4.2 7.6 22.8 0.2 11.8 3.3 3.8 4 0 0 4 4 4 0 Zinc ribbon domain Dynactin_p62 PF05502.13 KFQ95600.1 - 5.5 5.6 10.7 6.9 5.3 2.9 2.1 2 0 0 2 2 2 0 Dynactin p62 family zf-C2H2_12 PF18658.1 KFQ95600.1 - 9.7 5.9 9.3 3.8 7.2 1.7 2.9 3 0 0 3 3 3 0 Zinc-finger C2H2-type PH_15 PF17339.2 KFQ95601.1 - 3.1e-06 27.0 0.1 5.3e-06 26.3 0.1 1.4 1 1 0 1 1 1 1 PH domain PH PF00169.29 KFQ95601.1 - 1e-05 26.0 0.1 1.3e-05 25.6 0.1 1.1 1 0 0 1 1 1 1 PH domain MIT_C PF16565.5 KFQ95601.1 - 0.1 12.5 0.1 0.24 11.4 0.1 1.6 1 1 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT Troponin PF00992.20 KFQ95602.1 - 2.2e-49 167.2 7.4 3.1e-49 166.7 7.4 1.2 1 0 0 1 1 1 1 Troponin Tup_N PF08581.10 KFQ95602.1 - 0.022 15.1 2.6 0.032 14.5 0.1 2.3 2 0 0 2 2 2 0 Tup N-terminal XkdW PF09636.10 KFQ95602.1 - 0.081 13.0 1.9 0.35 11.0 1.7 2.1 1 1 0 1 1 1 0 XkdW protein DUF2951 PF11166.8 KFQ95602.1 - 0.2 11.9 4.3 0.62 10.3 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Med9 PF07544.13 KFQ95602.1 - 0.83 9.8 6.7 14 5.9 1.3 2.9 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Troponin PF00992.20 KFQ95603.1 - 1.5e-37 128.9 47.5 1e-33 116.5 36.9 2.0 1 1 1 2 2 2 2 Troponin DUF4250 PF14056.6 KFQ95603.1 - 0.036 14.0 0.7 0.092 12.7 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) Arm PF00514.23 KFQ95604.1 - 2.1e-29 100.6 6.2 2.2e-09 37.0 0.0 7.6 9 0 0 9 9 9 5 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KFQ95604.1 - 7e-07 29.6 2.9 0.06 13.9 0.1 5.1 5 0 0 5 5 5 2 HEAT-like repeat HEAT PF02985.22 KFQ95604.1 - 0.0019 18.3 1.5 1.9 8.9 0.1 4.0 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 KFQ95604.1 - 0.0031 17.9 0.4 0.21 12.0 0.1 3.0 2 1 1 3 3 3 1 HEAT repeats V-ATPase_H_C PF11698.8 KFQ95604.1 - 0.0086 16.2 0.1 0.041 14.0 0.0 2.2 2 0 0 2 2 2 1 V-ATPase subunit H Adaptin_N PF01602.20 KFQ95604.1 - 0.015 13.9 0.9 3.7 6.0 0.0 2.6 1 1 0 2 2 2 0 Adaptin N terminal region Mo25 PF08569.11 KFQ95604.1 - 0.021 14.2 0.1 0.052 12.9 0.0 1.6 2 0 0 2 2 2 0 Mo25-like Arm_2 PF04826.13 KFQ95604.1 - 0.16 11.4 0.6 0.91 8.9 0.1 2.3 2 1 0 2 2 2 0 Armadillo-like fn3 PF00041.21 KFQ95605.1 - 7.9e-60 199.2 10.0 7.7e-17 61.4 0.0 4.6 4 0 0 4 4 4 4 Fibronectin type III domain I-set PF07679.16 KFQ95605.1 - 9.5e-56 185.9 0.8 4.8e-19 68.2 0.0 6.3 7 0 0 7 7 7 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ95605.1 - 9e-34 115.9 8.5 1.1e-13 51.6 0.1 6.7 8 0 0 8 8 8 4 Immunoglobulin domain Ig_2 PF13895.6 KFQ95605.1 - 2.3e-17 63.1 0.0 5.4e-08 33.1 0.1 4.6 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 KFQ95605.1 - 3.9e-15 55.8 2.0 0.0011 19.1 0.0 5.6 6 0 0 6 6 6 3 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFQ95605.1 - 1e-13 51.7 8.0 0.032 14.8 1.0 5.6 5 1 0 5 5 5 4 Purple acid Phosphatase, N-terminal domain Tissue_fac PF01108.17 KFQ95605.1 - 8e-13 48.2 0.5 0.0008 19.2 0.0 4.5 4 0 0 4 4 4 3 Tissue factor fn3_4 PF16794.5 KFQ95605.1 - 8.1e-09 35.3 0.0 0.67 9.9 0.0 4.7 4 0 0 4 4 4 3 Fibronectin-III type domain Receptor_2B4 PF11465.8 KFQ95605.1 - 7.1e-08 32.6 0.4 0.027 14.7 0.0 4.6 5 0 0 5 5 5 2 Natural killer cell receptor 2B4 V-set PF07686.17 KFQ95605.1 - 9.1e-06 25.8 0.9 4.1 7.6 0.0 6.4 5 3 1 6 6 5 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFQ95605.1 - 1.2e-05 25.3 0.1 0.059 13.4 0.0 3.6 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain DUF2369 PF10179.9 KFQ95605.1 - 2.7e-05 24.5 0.0 8.2 6.9 0.0 4.7 5 0 0 5 5 5 1 Uncharacterised conserved protein (DUF2369) SusE PF14292.6 KFQ95605.1 - 4.9e-05 23.5 4.6 0.087 13.1 0.4 3.8 3 1 1 4 4 4 2 SusE outer membrane protein PhoD_N PF16655.5 KFQ95605.1 - 9.8e-05 22.8 0.0 0.08 13.5 0.0 3.9 4 0 0 4 4 4 1 PhoD-like phosphatase, N-terminal domain Y_Y_Y PF07495.13 KFQ95605.1 - 0.0034 17.3 1.6 1 9.4 0.3 3.6 4 0 0 4 4 3 1 Y_Y_Y domain DUF4945 PF16303.5 KFQ95605.1 - 0.088 12.7 0.1 1.1 9.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4945) Tmemb_9 PF05434.11 KFQ95606.1 - 2.2e-53 180.1 0.1 3.3e-53 179.5 0.1 1.3 1 0 0 1 1 1 1 TMEM9 F-box-like PF12937.7 KFQ95607.1 - 0.036 13.9 2.6 0.08 12.9 2.6 1.6 1 0 0 1 1 1 0 F-box-like SAM_1 PF00536.30 KFQ95608.1 - 6.9e-27 93.7 1.4 3.9e-13 49.6 0.2 4.0 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFQ95608.1 - 2.1e-25 88.6 1.1 6.8e-11 42.1 0.1 4.0 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) CREPT PF16566.5 KFQ95608.1 - 0.003 17.8 9.8 0.003 17.8 9.8 5.5 3 2 2 5 5 5 1 Cell-cycle alteration and expression-elevated protein in tumour FlxA PF14282.6 KFQ95608.1 - 0.22 11.5 0.0 0.22 11.5 0.0 5.7 3 1 1 4 4 4 0 FlxA-like protein DUF2087 PF09860.9 KFQ95608.1 - 4.2 7.6 7.6 0.82 9.9 0.3 3.5 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2087) T2SSF PF00482.23 KFQ95608.1 - 4.5 7.2 15.4 0.55 10.2 4.6 3.9 4 0 0 4 4 4 0 Type II secretion system (T2SS), protein F HWE_HK PF07536.14 KFQ95608.1 - 7.4 7.4 16.2 0.18 12.5 2.5 4.5 3 1 0 4 4 4 0 HWE histidine kinase Basic PF01586.16 KFQ95609.1 - 1.8e-31 109.2 0.0 3.5e-31 108.2 0.0 1.5 1 0 0 1 1 1 1 Myogenic Basic domain HLH PF00010.26 KFQ95609.1 - 6.1e-13 48.5 5.9 1e-12 47.8 5.9 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3080 PF11279.8 KFQ95609.1 - 0.0015 17.8 0.3 0.002 17.4 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3080) 7tm_1 PF00001.21 KFQ95610.1 - 1.4e-44 152.4 15.1 1.6e-44 152.2 15.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ95610.1 - 1.1e-10 41.3 12.6 7.3e-10 38.7 12.6 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFQ95610.1 - 5.7e-10 39.4 6.4 7.3e-10 39.0 6.4 1.2 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFQ95610.1 - 9.9e-08 31.9 15.1 1.8e-07 31.0 14.5 1.8 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx UPF0182 PF03699.13 KFQ95610.1 - 0.1 10.7 8.1 0.11 10.6 8.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) CcmH PF03918.14 KFQ95610.1 - 0.17 11.1 0.5 0.79 9.0 0.0 2.2 3 0 0 3 3 3 0 Cytochrome C biogenesis protein Renin_r PF07850.14 KFQ95610.1 - 0.27 11.8 0.1 0.27 11.8 0.1 1.9 2 0 0 2 2 2 0 Renin receptor-like protein DENN PF02141.21 KFQ95611.1 - 1.6e-57 194.5 2.1 3.3e-57 193.5 2.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KFQ95611.1 - 1e-15 58.2 0.0 2.2e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KFQ95611.1 - 6.4e-10 38.9 2.2 1.3e-09 37.9 2.2 1.5 1 0 0 1 1 1 1 dDENN domain 7tm_6 PF02949.20 KFQ95611.1 - 0.024 13.7 0.1 0.056 12.5 0.0 1.6 1 1 0 1 1 1 0 7tm Odorant receptor DUF2164 PF09932.9 KFQ95611.1 - 0.045 13.8 0.0 0.19 11.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2164) SPA PF08616.10 KFQ95611.1 - 0.11 12.5 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis CDP-OH_P_transf PF01066.21 KFQ95612.1 - 1.2e-18 67.6 0.1 1.2e-18 67.6 0.1 3.1 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Frag1 PF10277.9 KFQ95613.1 - 4.2e-37 127.8 16.1 5e-37 127.6 16.1 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family TssN PF17555.2 KFQ95613.1 - 0.11 11.9 12.4 0.17 11.2 12.4 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF3989 PF13150.6 KFQ95613.1 - 0.91 9.3 4.6 8.6 6.2 0.3 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF3989) Ank_2 PF12796.7 KFQ95614.1 - 4.6e-35 120.1 2.2 7.1e-12 45.8 0.2 4.4 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ95614.1 - 5.7e-34 116.1 3.5 2.9e-11 43.6 0.1 6.2 3 1 3 6 6 6 5 Ankyrin repeats (many copies) HECT PF00632.25 KFQ95614.1 - 4.6e-29 101.9 0.3 3.1e-28 99.2 0.0 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Ank_3 PF13606.6 KFQ95614.1 - 2.9e-28 94.8 3.6 1.6e-05 24.9 0.0 7.6 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 KFQ95614.1 - 1.6e-27 94.7 11.3 1.2e-06 28.6 0.1 7.7 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 KFQ95614.1 - 2.4e-23 81.9 5.2 1.5e-07 31.6 0.1 3.9 2 1 1 4 4 4 4 Ankyrin repeats (many copies) CSD PF00313.22 KFQ95615.1 - 1e-17 63.7 0.1 2.2e-17 62.7 0.1 1.6 1 1 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-CCHC PF00098.23 KFQ95615.1 - 9.9e-09 34.9 13.8 6.8e-05 22.8 2.7 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 KFQ95615.1 - 0.43 10.4 10.4 0.15 11.8 1.6 2.3 2 0 0 2 2 2 0 Zinc knuckle Peptidase_S9_N PF02897.15 KFQ95616.1 - 1.4e-143 478.6 0.0 1.7e-143 478.4 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 KFQ95616.1 - 9.2e-68 227.9 0.0 1.4e-67 227.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KFQ95616.1 - 0.077 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative esterase zf-H2C2_2 PF13465.6 KFQ95617.1 - 9e-26 89.1 43.5 1.1e-07 31.9 1.1 5.6 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ95617.1 - 2.2e-12 46.7 42.6 1.8e-05 24.9 0.4 5.7 5 0 0 5 5 5 4 Zinc finger, C2H2 type SET PF00856.28 KFQ95617.1 - 2.4e-07 31.3 0.2 9.7e-07 29.3 0.2 1.9 1 1 0 1 1 1 1 SET domain zf-C2H2_4 PF13894.6 KFQ95617.1 - 8.3e-06 26.2 42.4 0.012 16.3 0.5 5.7 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFQ95617.1 - 0.0052 16.8 0.7 0.0052 16.8 0.7 5.5 5 0 0 5 5 5 2 C2H2-type zinc finger FYVE PF01363.21 KFQ95617.1 - 1.3 9.2 16.0 2.3 8.4 2.1 3.3 2 1 0 2 2 2 0 FYVE zinc finger Zn-ribbon_8 PF09723.10 KFQ95617.1 - 1.6 8.9 13.8 4.7 7.4 1.5 3.7 3 0 0 3 3 3 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 KFQ95617.1 - 4 7.8 28.3 1.4 9.3 0.8 5.2 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding APG5 PF04106.12 KFQ95618.1 - 5e-61 206.2 0.6 6.4e-61 205.8 0.6 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Crystall PF00030.19 KFQ95620.1 - 4.5e-127 414.5 0.7 2.3e-28 98.2 0.0 6.3 6 0 0 6 6 6 6 Beta/Gamma crystallin IL4_i_Ig PF18258.1 KFQ95620.1 - 3.8e-18 65.5 6.3 0.019 15.2 0.1 8.6 6 3 2 8 8 8 5 Interleukin-4 inducing immunoglobulin-binding domain Ricin_B_lectin PF00652.22 KFQ95620.1 - 7.3e-11 42.4 0.0 1.3e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KFQ95620.1 - 0.00015 22.4 0.0 0.14 12.9 0.0 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Inhibitor_I36 PF03995.13 KFQ95620.1 - 0.033 14.1 0.1 16 5.5 0.0 4.7 6 0 0 6 6 6 0 Peptidase inhibitor family I36 ADH_zinc_N_2 PF13602.6 KFQ95621.1 - 2.8e-23 83.5 0.0 4.2e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFQ95621.1 - 4.8e-15 55.7 0.0 1.2e-14 54.4 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFQ95621.1 - 1.4e-08 34.6 0.0 4.2e-08 33.0 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 KFQ95621.1 - 0.0086 15.8 0.2 0.014 15.2 0.2 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase adh_short PF00106.25 KFQ95621.1 - 0.027 13.9 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase THF_DHG_CYH_C PF02882.19 KFQ95621.1 - 0.038 13.3 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 KFQ95621.1 - 0.063 13.0 0.2 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Amidase PF01425.21 KFQ95622.1 - 4.9e-128 427.9 0.0 2.2e-127 425.8 0.0 1.8 1 1 0 1 1 1 1 Amidase FAM176 PF14851.6 KFQ95623.1 - 0.013 15.2 1.9 0.024 14.3 1.9 1.4 1 0 0 1 1 1 0 FAM176 family BEN PF10523.9 KFQ95624.1 - 9.3e-71 234.1 4.6 4e-21 75.0 0.0 4.5 4 0 0 4 4 4 4 BEN domain polyprenyl_synt PF00348.17 KFQ95625.1 - 5.9e-20 71.4 0.1 9.4e-20 70.7 0.1 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase VirK PF06903.12 KFQ95625.1 - 0.0059 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 VirK protein SOBP PF15279.6 KFQ95626.1 - 3.4e-91 307.2 39.9 3.4e-91 307.2 39.9 3.3 3 1 0 3 3 3 1 Sine oculis-binding protein zf-FCS PF06467.14 KFQ95626.1 - 0.0033 17.3 12.2 0.17 11.8 1.5 2.7 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif zf-C6H2 PF15801.5 KFQ95626.1 - 0.65 10.4 9.8 2 8.8 6.1 2.9 2 1 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding SLED PF12140.8 KFQ95627.1 - 2.8e-35 121.2 0.6 4.1e-35 120.7 0.6 1.2 1 0 0 1 1 1 1 SLED domain SAM_1 PF00536.30 KFQ95627.1 - 9.4e-15 54.8 0.1 1.8e-14 53.9 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RBR PF17208.3 KFQ95627.1 - 3.3e-11 43.7 9.6 7.5e-11 42.6 9.6 1.7 1 0 0 1 1 1 1 RNA binding Region SAM_2 PF07647.17 KFQ95627.1 - 0.00063 19.8 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFQ95627.1 - 0.011 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Sec63 PF02889.16 KFQ95628.1 - 6e-20 71.5 3.2 4.3e-09 35.9 0.8 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DnaJ PF00226.31 KFQ95628.1 - 2.7e-17 62.6 0.0 9.1e-17 61.0 0.0 2.0 1 0 0 1 1 1 1 DnaJ domain OSTMP1 PF09777.9 KFQ95629.1 - 2.6e-74 249.6 9.3 2.9e-74 249.4 9.3 1.0 1 0 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor CECR6_TMEM121 PF14997.6 KFQ95629.1 - 0.0011 18.9 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 CECR6/TMEM121 family Hormone_recep PF00104.30 KFQ95630.1 - 1.8e-34 119.1 0.0 2.2e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFQ95630.1 - 4.1e-18 65.6 2.5 1.6e-17 63.7 2.3 2.0 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) C1_2 PF03107.16 KFQ95630.1 - 5.3 7.4 6.6 1.3 9.4 2.6 2.0 2 1 0 2 2 2 0 C1 domain PX PF00787.24 KFQ95631.1 - 2e-22 79.3 0.2 2.2e-22 79.2 0.2 1.1 1 0 0 1 1 1 1 PX domain RdRP_1 PF00680.20 KFQ95631.1 - 0.033 12.7 0.0 0.036 12.6 0.0 1.0 1 0 0 1 1 1 0 RNA dependent RNA polymerase AFG1_ATPase PF03969.16 KFQ95632.1 - 4.3e-115 384.4 4.1 2.6e-111 372.0 0.8 2.0 1 1 1 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 KFQ95632.1 - 8e-05 23.1 0.1 0.039 14.3 0.0 2.8 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.29 KFQ95632.1 - 0.00013 22.4 0.1 0.0011 19.4 0.0 2.6 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFQ95632.1 - 0.0027 18.0 0.1 0.011 16.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 KFQ95632.1 - 0.0034 17.0 0.0 0.023 14.2 0.0 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_14 PF13173.6 KFQ95632.1 - 0.012 15.7 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFQ95632.1 - 0.022 14.7 0.0 0.088 12.7 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 KFQ95632.1 - 0.025 14.9 0.1 1.2 9.5 0.1 2.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFQ95632.1 - 0.065 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 KFQ95632.1 - 0.078 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 KFQ95632.1 - 0.097 12.6 0.1 0.27 11.1 0.1 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Mrx7 PF10906.8 KFQ95632.1 - 0.12 12.7 0.2 0.39 11.0 0.0 1.9 2 0 0 2 2 2 0 MIOREX complex component 7 Arm PF00514.23 KFQ95633.1 - 8.1e-10 38.4 5.8 0.79 9.9 0.1 7.0 6 0 0 6 6 6 4 Armadillo/beta-catenin-like repeat PUL PF08324.11 KFQ95633.1 - 1.1e-05 24.8 3.0 0.00057 19.2 1.1 3.3 2 1 1 3 3 3 1 PUL domain KAP PF05804.12 KFQ95633.1 - 0.00079 17.7 18.9 0.012 13.8 2.7 3.0 2 2 1 3 3 3 2 Kinesin-associated protein (KAP) Cep57_CLD PF14073.6 KFQ95634.1 - 2.8e-64 216.4 36.7 2.8e-64 216.4 36.7 2.8 3 0 0 3 3 3 1 Centrosome localisation domain of Cep57 Cep57_MT_bd PF06657.13 KFQ95634.1 - 2.9e-18 66.1 4.2 2.9e-18 66.1 4.2 4.1 2 1 2 4 4 4 1 Centrosome microtubule-binding domain of Cep57 STELLO PF03385.17 KFQ95634.1 - 0.0089 14.9 0.2 0.0089 14.9 0.2 1.9 2 1 0 2 2 2 1 STELLO glycosyltransferases DUF4549 PF15082.6 KFQ95635.1 - 6.8e-20 71.3 5.6 7.8e-20 71.1 5.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4549) CtaG_Cox11 PF04442.14 KFQ95636.1 - 0.17 11.9 0.0 0.62 10.1 0.0 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein CtaG/Cox11 MGC-24 PF05283.11 KFQ95637.1 - 1.1e-30 106.9 23.0 9.4e-30 103.9 23.0 1.9 1 1 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4366 PF14283.6 KFQ95637.1 - 0.015 15.3 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) FAM220 PF15487.6 KFQ95637.1 - 0.14 11.7 1.5 0.18 11.4 1.5 1.1 1 0 0 1 1 1 0 FAM220 family SOG2 PF10428.9 KFQ95637.1 - 0.65 9.1 9.5 0.7 9.0 9.5 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Pro_isomerase PF00160.21 KFQ95638.1 - 1.2e-42 145.9 0.0 1.5e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4303 PF14136.6 KFQ95638.1 - 0.022 14.5 0.1 0.036 13.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) ADK PF00406.22 KFQ95639.1 - 6.1e-17 62.1 0.0 9.5e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KFQ95639.1 - 1e-12 48.7 0.0 2e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain FAP206 PF12018.8 KFQ95639.1 - 5.3e-11 42.5 1.8 7.6e-06 25.6 0.0 3.2 2 1 1 3 3 3 2 Domain of unknown function YHS PF04945.13 KFQ95639.1 - 2.3e-10 40.4 0.8 0.0092 16.1 0.1 3.4 3 0 0 3 3 3 3 YHS domain AAA_18 PF13238.6 KFQ95639.1 - 0.0014 19.1 0.3 0.013 16.1 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 KFQ95639.1 - 0.0072 16.1 0.1 0.012 15.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KFQ95639.1 - 0.0097 16.2 0.1 0.067 13.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFQ95639.1 - 0.02 15.0 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KFQ95639.1 - 0.052 13.0 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Cytidylate_kin PF02224.18 KFQ95639.1 - 0.054 13.2 0.0 0.094 12.4 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase G-alpha PF00503.20 KFQ95639.1 - 0.074 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_22 PF13401.6 KFQ95639.1 - 0.17 12.2 0.1 0.36 11.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain Josephin PF02099.17 KFQ95639.1 - 0.18 11.9 0.5 0.41 10.7 0.5 1.5 1 0 0 1 1 1 0 Josephin ADK PF00406.22 KFQ95640.1 - 1.4e-12 47.9 0.1 1.4e-08 34.9 0.1 2.2 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 KFQ95640.1 - 7.7e-12 45.8 0.0 1.5e-05 25.4 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA_18 PF13238.6 KFQ95640.1 - 6.8e-10 39.6 0.1 4e-09 37.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain FAP206 PF12018.8 KFQ95640.1 - 4.5e-06 26.4 1.2 3.7e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function AAA PF00004.29 KFQ95640.1 - 1.3e-05 25.6 0.1 2.1e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KFQ95640.1 - 1.5e-05 25.3 0.1 4.2e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFQ95640.1 - 0.00068 19.8 0.2 0.0032 17.6 0.2 2.3 1 1 0 1 1 1 1 AAA domain YHS PF04945.13 KFQ95640.1 - 0.00076 19.5 4.4 0.0024 17.9 1.9 2.5 1 1 1 2 2 2 1 YHS domain G-alpha PF00503.20 KFQ95640.1 - 0.0043 16.3 0.1 0.0051 16.0 0.1 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_24 PF13479.6 KFQ95640.1 - 0.0065 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KFQ95640.1 - 0.015 15.2 0.0 0.082 12.8 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 KFQ95640.1 - 0.016 15.2 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SKI PF01202.22 KFQ95640.1 - 0.018 15.2 0.2 0.053 13.7 0.0 1.9 2 1 0 2 2 2 0 Shikimate kinase TsaE PF02367.17 KFQ95640.1 - 0.022 14.8 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KFQ95640.1 - 0.034 14.4 0.3 0.26 11.6 0.1 2.2 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFQ95640.1 - 0.09 13.3 0.5 0.18 12.3 0.5 1.7 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 KFQ95640.1 - 0.093 12.8 2.3 0.24 11.4 0.3 2.7 2 1 0 2 2 2 0 AAA domain ADK PF00406.22 KFQ95641.1 - 7.9e-21 74.7 0.3 5.9e-19 68.7 0.1 2.5 2 0 0 2 2 2 1 Adenylate kinase AAA_17 PF13207.6 KFQ95641.1 - 5.1e-11 43.1 1.8 5.9e-09 36.5 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KFQ95641.1 - 6.6e-07 29.9 1.3 0.00028 21.5 0.8 3.0 2 1 1 3 3 3 1 AAA domain AAA PF00004.29 KFQ95641.1 - 1.2e-05 25.8 0.2 0.17 12.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Hydin_ADK PF17213.3 KFQ95641.1 - 1.7e-05 25.2 0.1 0.033 14.5 0.0 2.5 2 1 0 2 2 2 2 Hydin Adenylate kinase-like domain NACHT PF05729.12 KFQ95641.1 - 0.0009 19.2 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.27 KFQ95641.1 - 0.00098 19.7 1.4 0.33 11.4 0.0 3.2 3 0 0 3 3 3 1 ABC transporter KTI12 PF08433.10 KFQ95641.1 - 0.0028 17.1 2.0 0.47 9.8 0.0 3.1 3 0 0 3 3 3 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 KFQ95641.1 - 0.0034 17.8 1.3 0.94 9.8 1.8 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KFQ95641.1 - 0.0051 16.8 0.0 0.083 12.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) FAP206 PF12018.8 KFQ95641.1 - 0.0051 16.4 1.9 0.011 15.3 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function RuvB_N PF05496.12 KFQ95641.1 - 0.0077 16.0 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFQ95641.1 - 0.0092 16.3 0.1 0.69 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KFQ95641.1 - 0.019 14.3 0.0 0.1 11.9 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SKI PF01202.22 KFQ95641.1 - 0.031 14.4 0.2 0.27 11.4 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase Herpes_Helicase PF02689.14 KFQ95641.1 - 0.049 11.6 0.0 0.083 10.8 0.0 1.3 1 0 0 1 1 1 0 Helicase AAA_33 PF13671.6 KFQ95641.1 - 0.052 13.7 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFQ95641.1 - 0.091 13.2 0.2 7.8 6.9 0.0 3.1 3 0 0 3 3 3 0 RNA helicase AAA_24 PF13479.6 KFQ95641.1 - 0.12 12.1 0.1 8 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KFQ95641.1 - 0.13 11.6 0.0 0.43 9.8 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 KFQ95641.1 - 0.18 11.5 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KFQ95641.1 - 0.18 11.7 0.2 6.2 6.7 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_28 PF13521.6 KFQ95641.1 - 0.2 11.9 1.8 2.8 8.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain FAM176 PF14851.6 KFQ95641.1 - 0.41 10.3 4.5 0.72 9.5 4.5 1.3 1 0 0 1 1 1 0 FAM176 family Syja_N PF02383.18 KFQ95642.1 - 2e-73 247.5 0.0 3.8e-73 246.6 0.0 1.5 1 0 0 1 1 1 1 SacI homology domain 7tm_1 PF00001.21 KFQ95643.1 - 1.4e-33 116.4 17.0 1.7e-33 116.1 17.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFQ95643.1 - 3e-05 23.9 15.7 0.00048 20.0 15.7 2.5 1 1 0 1 1 1 1 Olfactory receptor WH2 PF02205.20 KFQ95644.1 - 1.7e-07 30.8 0.1 2.8e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 WH2 motif WD40 PF00400.32 KFQ95645.1 - 2.7e-37 126.1 11.9 2e-06 28.4 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ95645.1 - 2.2e-11 43.9 0.1 0.008 16.5 0.1 4.9 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFQ95645.1 - 0.0044 16.9 0.4 2.1 8.2 0.0 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 KFQ95645.1 - 0.045 13.3 0.0 0.15 11.6 0.0 1.8 2 1 1 3 3 3 0 PQQ-like domain Methyltransf_22 PF13383.6 KFQ95646.1 - 6.4e-12 45.6 0.4 7.3e-12 45.4 0.4 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 KFQ95646.1 - 1.7e-06 28.2 0.0 2.5e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain DAO PF01266.24 KFQ95648.1 - 7.1e-36 124.5 0.0 8.1e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFQ95648.1 - 0.011 16.3 0.1 0.36 11.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFQ95648.1 - 0.011 14.8 0.0 0.027 13.6 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 KFQ95648.1 - 0.011 14.9 0.1 0.018 14.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 KFQ95648.1 - 0.024 14.2 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.6 KFQ95648.1 - 0.028 14.6 0.0 0.11 12.7 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Glu_dehyd_C PF16912.5 KFQ95648.1 - 0.12 11.8 0.0 2.8 7.4 0.0 2.1 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Sugar_tr PF00083.24 KFQ95649.1 - 1.5e-22 80.1 25.6 2e-22 79.7 25.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFQ95649.1 - 2.2e-21 76.2 27.1 2.2e-21 76.2 27.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Pkinase PF00069.25 KFQ95650.1 - 4.4e-52 177.1 0.0 5.1e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ95650.1 - 3.6e-19 69.1 0.0 5.8e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFQ95650.1 - 0.011 15.6 0.1 0.019 14.9 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KFQ95650.1 - 0.059 12.7 0.1 0.092 12.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SAM_decarbox PF01536.16 KFQ95653.1 - 7.8e-112 373.8 2.7 8.8e-112 373.6 2.7 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase TFIIIC_sub6 PF10419.9 KFQ95654.1 - 7.9e-18 64.1 0.1 1.3e-17 63.4 0.1 1.4 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Brix PF04427.18 KFQ95655.1 - 2.8e-45 154.8 0.1 4.9e-45 154.0 0.1 1.4 1 0 0 1 1 1 1 Brix domain MFS_1 PF07690.16 KFQ95656.1 - 2.8e-35 121.9 40.1 1.4e-21 76.8 25.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KFQ95656.1 - 1.7e-06 27.6 3.2 2e-06 27.4 3.2 1.3 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF4683 PF15735.5 KFQ95657.1 - 9.1e-173 575.5 13.2 9.1e-173 575.5 13.2 5.8 6 1 0 6 6 6 1 Domain of unknown function (DUF4683) DNA_pol_B PF00136.21 KFQ95657.1 - 1.3e-97 327.5 0.2 2.2e-97 326.7 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KFQ95657.1 - 5.2e-27 94.9 0.2 1.4e-15 57.3 0.1 2.8 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KFQ95657.1 - 2.7e-13 50.2 11.6 2e-12 47.4 11.6 2.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta SEFIR PF08357.11 KFQ95658.1 - 5.1e-33 114.5 0.2 6.7e-33 114.1 0.2 1.2 1 0 0 1 1 1 1 SEFIR domain TIR_2 PF13676.6 KFQ95658.1 - 2.7e-05 24.7 0.0 4.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 TIR domain Pkinase_Tyr PF07714.17 KFQ95659.1 - 1.8e-92 309.3 0.0 2.4e-92 308.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ95659.1 - 2.3e-46 158.3 0.0 3.5e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFQ95659.1 - 5.8e-29 100.0 0.3 1.3e-28 98.9 0.3 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFQ95659.1 - 1.1e-20 72.9 0.3 6.2e-20 70.6 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFQ95659.1 - 2.2e-13 49.8 0.4 5.7e-13 48.5 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KFQ95659.1 - 7.8e-12 44.7 0.0 3e-11 42.8 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain Haspin_kinase PF12330.8 KFQ95659.1 - 0.0067 15.4 0.0 0.03 13.3 0.0 1.8 1 1 0 1 1 1 1 Haspin like kinase domain SH3_10 PF17902.1 KFQ95659.1 - 0.015 15.4 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 SH3 domain SH3_3 PF08239.11 KFQ95659.1 - 0.046 14.0 0.1 0.099 12.9 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain zf-RING_14 PF17978.1 KFQ95659.1 - 0.083 13.3 0.1 0.41 11.1 0.0 2.1 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain IGFBP PF00219.18 KFQ95661.1 - 1.7e-10 41.4 21.1 1.7e-10 41.4 21.1 4.2 3 2 0 3 3 3 1 Insulin-like growth factor binding protein Cys_knot PF00007.22 KFQ95661.1 - 1.9e-05 24.9 11.8 1.9e-05 24.9 11.8 3.5 2 1 1 3 3 3 1 Cystine-knot domain VWC PF00093.18 KFQ95661.1 - 0.00012 22.3 0.2 0.00012 22.3 0.2 4.9 4 2 0 4 4 4 1 von Willebrand factor type C domain Tubulin PF00091.25 KFQ95662.1 - 2.6e-64 217.1 0.0 3.8e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFQ95662.1 - 8.7e-31 106.7 0.0 1.5e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 KFQ95662.1 - 5.2e-06 25.9 0.0 7.8e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin like Tubulin_3 PF14881.6 KFQ95662.1 - 0.0061 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Laminin_G_2 PF02210.24 KFQ95663.1 - 1.4e-92 306.8 0.0 2.3e-22 79.9 0.1 5.6 5 0 0 5 5 5 5 Laminin G domain Laminin_G_1 PF00054.23 KFQ95663.1 - 1.8e-73 244.9 0.0 1.7e-19 70.4 0.0 5.6 5 0 0 5 5 5 5 Laminin G domain Laminin_II PF06009.12 KFQ95663.1 - 6.4e-32 110.5 2.9 6.4e-32 110.5 2.9 5.9 2 1 3 5 5 5 2 Laminin Domain II Laminin_I PF06008.14 KFQ95663.1 - 3.2e-31 109.0 27.0 3.2e-31 109.0 27.0 3.8 2 2 2 4 4 4 2 Laminin Domain I Laminin_EGF PF00053.24 KFQ95663.1 - 5.1e-22 77.8 66.7 7.7e-11 42.0 10.4 4.8 4 1 1 5 5 5 3 Laminin EGF domain Laminin_G_3 PF13385.6 KFQ95663.1 - 2.1e-16 60.5 0.1 1e-06 29.0 0.0 5.2 5 0 0 5 5 5 2 Concanavalin A-like lectin/glucanases superfamily AnfO_nitrog PF09582.10 KFQ95663.1 - 0.15 11.4 2.9 0.38 10.1 2.9 1.6 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) PTS_IIA PF02255.16 KFQ95663.1 - 0.79 9.8 4.4 1.1 9.4 0.6 3.2 3 0 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit Gasdermin_C PF17708.1 KFQ95663.1 - 1.1 9.4 9.5 0.23 11.6 5.8 1.8 2 0 0 2 2 2 0 Gasdermin PUB domain kleA_kleC PF17383.2 KFQ95663.1 - 1.1 9.6 7.0 1.5 9.2 1.7 3.3 2 1 1 3 3 3 0 Uncharacterized KorC regulated protein A Ig_3 PF13927.6 KFQ95664.1 - 3.1e-14 53.3 0.5 9.5e-10 38.9 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFQ95664.1 - 6.4e-13 48.6 0.1 1.9e-09 37.5 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFQ95664.1 - 1e-10 41.6 0.4 7.9e-07 29.2 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFQ95664.1 - 4.2e-09 36.6 0.7 5.6e-06 26.5 0.0 3.2 2 2 1 3 3 3 2 Immunoglobulin V-set domain Ig_4 PF16680.5 KFQ95664.1 - 4.9e-07 29.9 0.2 0.023 14.9 0.1 2.5 2 0 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain Ig_2 PF13895.6 KFQ95664.1 - 6.8e-07 29.5 0.2 0.013 15.8 0.0 2.3 1 1 1 2 2 2 2 Immunoglobulin domain V-set_CD47 PF08204.11 KFQ95664.1 - 0.00016 21.6 2.6 0.015 15.3 0.7 2.7 2 1 0 2 2 2 2 CD47 immunoglobulin-like domain Adeno_E3_CR1 PF02440.15 KFQ95664.1 - 0.017 14.9 0.4 0.049 13.4 0.1 2.0 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 Thioredoxin PF00085.20 KFQ95665.1 - 3.2e-09 36.7 0.0 9.9e-07 28.7 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin DnaJ PF00226.31 KFQ95665.1 - 4.3e-09 36.4 0.0 1e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Thioredoxin_3 PF13192.6 KFQ95665.1 - 0.028 14.5 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain IRK PF01007.20 KFQ95665.1 - 0.04 13.7 0.1 0.08 12.8 0.1 1.4 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain Arginase PF00491.21 KFQ95666.1 - 4.8e-92 308.4 0.0 5.8e-92 308.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family Corona_6B_7B PF03262.13 KFQ95666.1 - 0.09 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Coronavirus 6B/7B protein UPF0489 PF12640.7 KFQ95666.1 - 0.17 12.1 0.1 0.26 11.5 0.1 1.2 1 0 0 1 1 1 0 UPF0489 domain Pkinase PF00069.25 KFQ95667.1 - 3.8e-25 88.7 0.0 8.8e-25 87.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ95667.1 - 1.2e-14 54.2 0.0 3.4e-14 52.7 0.0 1.7 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ95667.1 - 0.00098 18.5 0.0 0.0023 17.3 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KFQ95667.1 - 0.031 14.2 0.1 0.062 13.2 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family dCMP_cyt_deam_1 PF00383.23 KFQ95668.1 - 1.6e-10 40.7 0.1 1.9e-10 40.5 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KFQ95668.1 - 0.00017 21.8 0.8 0.13 12.5 0.0 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 KFQ95668.1 - 0.016 14.9 2.0 0.46 10.1 0.2 2.0 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases PID_2 PF14719.6 KFQ95669.1 - 5e-69 231.8 0.5 6.8e-69 231.4 0.5 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.23 KFQ95669.1 - 0.00047 20.2 0.0 0.00075 19.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) GIDE PF12483.8 KFQ95670.1 - 1.2e-22 80.0 0.1 1.8e-22 79.4 0.1 1.3 1 0 0 1 1 1 1 E3 Ubiquitin ligase zf-C3HC4_3 PF13920.6 KFQ95670.1 - 8e-13 48.0 15.0 1.3e-12 47.3 15.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFQ95670.1 - 8.3e-06 25.6 14.5 1.4e-05 24.8 14.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KFQ95670.1 - 0.00018 21.8 16.2 0.00039 20.7 16.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFQ95670.1 - 0.00051 20.0 15.2 0.00092 19.1 15.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain LapA_dom PF06305.11 KFQ95670.1 - 0.0083 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Peptidase_S49_N PF08496.10 KFQ95670.1 - 0.073 13.1 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal zf-C3HC4_2 PF13923.6 KFQ95670.1 - 0.09 12.6 15.2 0.17 11.7 15.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) VIT_2 PF13757.6 KFQ95671.1 - 4e-28 97.1 0.0 8.2e-28 96.1 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KFQ95671.1 - 7.7e-28 97.4 0.0 1.6e-27 96.4 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KFQ95671.1 - 2e-07 31.4 0.0 3.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFQ95671.1 - 2.8e-07 31.2 0.0 7.2e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 KFQ95671.1 - 8.2e-07 29.2 0.0 1.6e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain DEAD PF00270.29 KFQ95672.1 - 4.7e-29 101.4 0.0 8e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFQ95672.1 - 1.9e-26 92.6 0.0 5.9e-26 91.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFQ95672.1 - 0.0002 21.4 0.0 0.00042 20.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UBX PF00789.20 KFQ95673.1 - 4.5e-10 39.6 0.0 8.2e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 UBX domain Phospholip_A2_1 PF00068.19 KFQ95674.1 - 1.2e-22 80.5 2.7 1.3e-22 80.4 2.7 1.0 1 0 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.10 KFQ95674.1 - 0.057 13.6 0.0 0.066 13.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP1 Phospholip_A2_2 PF05826.12 KFQ95674.1 - 0.13 12.5 7.1 0.19 12.0 7.0 1.4 1 1 0 1 1 1 0 Phospholipase A2 Phospholip_A2_1 PF00068.19 KFQ95675.1 - 6.2e-22 78.2 5.5 6.6e-22 78.1 5.5 1.0 1 0 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.10 KFQ95675.1 - 0.03 14.5 0.0 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 Parvovirus coat protein VP1 Phospholip_A2_2 PF05826.12 KFQ95675.1 - 0.083 13.1 6.8 0.12 12.6 6.7 1.4 1 1 0 1 1 1 0 Phospholipase A2 OTU PF02338.19 KFQ95676.1 - 1.3e-10 41.8 0.0 4.6e-10 40.1 0.0 2.0 2 1 0 2 2 2 1 OTU-like cysteine protease UBA_4 PF14555.6 KFQ95676.1 - 0.0058 16.4 0.2 0.01 15.7 0.2 1.4 1 0 0 1 1 1 1 UBA-like domain Peptidase_C65 PF10275.9 KFQ95676.1 - 0.049 13.1 4.8 0.2 11.1 0.0 2.9 2 1 1 3 3 3 0 Peptidase C65 Otubain DUF726 PF05277.12 KFQ95677.1 - 4.4e-130 433.6 3.7 5.6e-130 433.2 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF900 PF05990.12 KFQ95677.1 - 0.00023 20.8 0.0 0.00036 20.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.15 KFQ95677.1 - 0.0011 18.2 0.0 0.0018 17.5 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase VirJ PF06057.11 KFQ95677.1 - 0.0059 16.5 0.1 0.047 13.6 0.0 2.3 3 0 0 3 3 3 1 Bacterial virulence protein (VirJ) Palm_thioest PF02089.15 KFQ95677.1 - 0.025 14.4 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF4710 PF15828.5 KFQ95677.1 - 0.026 14.6 0.1 0.086 13.0 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) Sm_multidrug_ex PF06695.11 KFQ95677.1 - 0.038 14.6 3.2 0.15 12.7 3.2 2.0 1 1 0 1 1 1 0 Putative small multi-drug export protein DUF3089 PF11288.8 KFQ95677.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) PE-PPE PF08237.11 KFQ95677.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain 7tm_1 PF00001.21 KFQ95678.1 - 3.5e-65 220.0 12.1 4.4e-65 219.6 12.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ95678.1 - 1.4e-05 24.6 5.3 1.4e-05 24.6 5.3 2.5 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFQ95678.1 - 0.00042 20.2 9.6 0.0016 18.2 8.8 2.2 2 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFQ95678.1 - 0.0071 16.0 9.8 0.013 15.1 9.8 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF1385 PF07136.11 KFQ95678.1 - 0.11 11.8 0.7 0.35 10.1 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1385) DAN PF03045.15 KFQ95679.1 - 5.5e-24 84.4 7.6 7.4e-24 84.0 7.6 1.1 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.22 KFQ95679.1 - 1.1e-06 28.9 6.5 1.5e-06 28.5 6.5 1.1 1 0 0 1 1 1 1 Cystine-knot domain DUF543 PF04418.12 KFQ95680.1 - 1.5e-15 57.0 1.4 1.6e-15 56.8 1.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) F_actin_cap_B PF01115.17 KFQ95681.1 - 2.4e-110 367.8 0.0 2.8e-110 367.6 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.17 KFQ95681.1 - 0.045 13.2 0.0 0.5 9.7 0.0 2.6 1 1 0 1 1 1 0 F-actin capping protein alpha subunit Aldo_ket_red PF00248.21 KFQ95682.1 - 6.4e-55 186.4 0.0 7.2e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RL10P_insert PF17777.1 KFQ95683.1 - 5.7e-28 96.7 0.0 9.1e-28 96.1 0.0 1.2 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KFQ95683.1 - 5e-15 55.5 0.1 7e-15 55.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 Flavodoxin_4 PF12682.7 KFQ95683.1 - 0.11 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin TraF PF13728.6 KFQ95683.1 - 0.16 11.8 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein EMC1_C PF07774.13 KFQ95684.1 - 1.1e-72 244.2 0.2 2.5e-72 243.0 0.1 1.7 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KFQ95684.1 - 4.4e-10 39.6 0.5 8.6e-06 25.5 0.7 3.8 3 1 0 3 3 3 2 PQQ-like domain PQQ PF01011.21 KFQ95684.1 - 1.2e-06 28.1 0.1 0.16 11.9 0.0 3.6 3 0 0 3 3 3 2 PQQ enzyme repeat Filament PF00038.21 KFQ95685.1 - 1.2e-19 71.1 17.2 1.3e-10 41.4 1.4 2.1 2 0 0 2 2 2 2 Intermediate filament protein Snapin_Pallidin PF14712.6 KFQ95685.1 - 0.003 18.0 1.7 0.003 18.0 1.7 2.0 2 0 0 2 2 2 1 Snapin/Pallidin HIN PF02760.15 KFQ95685.1 - 0.046 13.4 0.2 0.088 12.5 0.2 1.3 1 0 0 1 1 1 0 HIN-200/IF120x domain Prefoldin PF02996.17 KFQ95685.1 - 0.14 12.1 4.6 6.2 6.8 0.2 2.7 2 0 0 2 2 2 0 Prefoldin subunit CdvA PF18822.1 KFQ95685.1 - 0.16 11.8 7.5 0.36 10.7 3.5 2.5 2 0 0 2 2 2 0 CdvA-like coiled-coil domain TLE_N PF03920.15 KFQ95685.1 - 0.96 9.5 5.6 0.23 11.5 0.3 2.5 2 1 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain FlaC_arch PF05377.11 KFQ95685.1 - 1.4 9.3 5.3 5.3 7.5 2.0 3.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF724 PF05266.14 KFQ95685.1 - 2.2 8.1 10.6 13 5.6 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF724) Rnk_N PF14760.6 KFQ95685.1 - 4.5 7.8 7.7 43 4.7 3.3 3.2 3 0 0 3 3 3 0 Rnk N-terminus Aldedh PF00171.22 KFQ95686.1 - 7.4e-100 334.6 0.0 9.2e-100 334.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PAX PF00292.18 KFQ95687.1 - 1.8e-75 250.8 0.9 2.9e-75 250.2 0.9 1.3 1 0 0 1 1 1 1 'Paired box' domain Homeodomain PF00046.29 KFQ95687.1 - 1.2e-23 82.7 7.0 2.6e-23 81.6 7.0 1.6 1 0 0 1 1 1 1 Homeodomain Pax7 PF12360.8 KFQ95687.1 - 7.4e-20 70.9 6.7 1.7e-19 69.7 6.7 1.7 1 0 0 1 1 1 1 Paired box protein 7 HTH_32 PF13565.6 KFQ95687.1 - 3.4e-05 24.4 6.1 0.0019 18.7 0.0 3.5 2 2 1 3 3 3 2 Homeodomain-like domain Homeobox_KN PF05920.11 KFQ95687.1 - 5.2e-05 23.1 1.6 9.1e-05 22.3 0.8 1.9 2 0 0 2 2 2 1 Homeobox KN domain HTH_23 PF13384.6 KFQ95687.1 - 9.4e-05 22.1 2.2 0.0012 18.6 0.1 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_IS1 PF12759.7 KFQ95687.1 - 0.14 11.8 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 InsA C-terminal domain RhoGEF PF00621.20 KFQ95688.1 - 5.8e-40 137.5 0.4 1.1e-39 136.6 0.4 1.5 1 0 0 1 1 1 1 RhoGEF domain IQ_SEC7_PH PF16453.5 KFQ95688.1 - 0.0043 17.0 0.0 0.0093 15.9 0.0 1.5 1 0 0 1 1 1 1 PH domain RCC1 PF00415.18 KFQ95689.1 - 6.3e-54 180.4 11.4 1e-15 58.1 0.0 6.4 7 1 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFQ95689.1 - 6.9e-31 105.4 12.7 3.6e-08 33.0 0.0 5.8 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 KFQ95689.1 - 0.04 14.4 0.1 0.67 10.4 0.0 2.6 2 1 1 3 3 3 0 SUKH-3 immunity protein PAD PF03068.15 KFQ95690.1 - 1.3e-144 482.0 0.0 1.1e-118 396.7 0.0 2.1 1 1 1 2 2 2 2 Protein-arginine deiminase (PAD) PAD_M PF08527.10 KFQ95690.1 - 2.1e-49 167.3 0.0 4.8e-49 166.1 0.0 1.6 1 1 0 1 1 1 1 Protein-arginine deiminase (PAD) middle domain PAD_N PF08526.10 KFQ95690.1 - 7.6e-23 81.0 0.0 1.4e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) N-terminal domain PAD PF03068.15 KFQ95691.1 - 5.5e-154 512.9 0.0 7.1e-154 512.5 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) PAD_M PF08527.10 KFQ95691.1 - 1.3e-57 193.9 0.0 2.4e-57 193.1 0.0 1.4 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) middle domain PAD_N PF08526.10 KFQ95691.1 - 9.6e-21 74.3 0.0 1.8e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) N-terminal domain PAD PF03068.15 KFQ95692.1 - 4.9e-165 549.2 0.0 5.9e-165 549.0 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) PAD_M PF08527.10 KFQ95692.1 - 1.8e-64 216.2 0.0 3e-64 215.5 0.0 1.3 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) middle domain PAD_N PF08526.10 KFQ95692.1 - 7.8e-29 100.3 0.0 1.3e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) N-terminal domain BpuJI_N PF11564.8 KFQ95692.1 - 0.13 11.4 0.1 0.2 10.8 0.1 1.2 1 0 0 1 1 1 0 Restriction endonuclease BpuJI - N terminal E1-E2_ATPase PF00122.20 KFQ95693.1 - 6.2e-37 126.9 0.1 1.7e-36 125.4 0.0 1.6 1 1 1 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 KFQ95693.1 - 0.00011 21.8 0.2 0.00032 20.3 0.1 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus LptF_LptG PF03739.14 KFQ95693.1 - 0.056 12.3 1.5 0.095 11.5 1.5 1.3 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG FLgD_tudor PF13861.6 KFQ95693.1 - 0.18 12.1 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 FlgD Tudor-like domain Hydrolase PF00702.26 KFQ95693.1 - 0.24 11.7 0.0 0.38 11.0 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase MARVEL PF01284.23 KFQ95693.1 - 0.81 9.7 8.1 0.13 12.3 0.8 2.3 2 1 0 2 2 2 0 Membrane-associating domain DUF1681 PF07933.14 KFQ95694.1 - 9.4e-42 142.2 0.0 1.1e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) SUZ PF12752.7 KFQ95695.1 - 5.3e-13 49.5 0.1 5.3e-13 49.5 0.1 2.6 3 0 0 3 3 3 1 SUZ domain SUZ-C PF12901.7 KFQ95695.1 - 1.3e-09 37.9 4.2 2.8e-09 36.8 4.2 1.6 1 0 0 1 1 1 1 SUZ-C motif Kelch_4 PF13418.6 KFQ95696.1 - 8.7e-28 96.1 0.6 7.9e-08 32.2 0.1 5.6 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KFQ95696.1 - 7.2e-26 89.9 5.7 2.2e-08 34.2 0.1 6.1 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KFQ95696.1 - 2.8e-23 81.4 3.2 7.7e-08 32.2 0.0 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KFQ95696.1 - 3.5e-19 67.9 9.1 3.2e-08 33.2 0.2 6.5 7 0 0 7 7 7 3 Kelch motif Kelch_1 PF01344.25 KFQ95696.1 - 1.3e-18 66.2 0.1 6.5e-06 25.6 0.0 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 KFQ95696.1 - 1.5e-18 66.4 6.0 0.00029 21.0 0.0 5.5 5 0 0 5 5 5 4 Kelch motif F-box-like PF12937.7 KFQ95696.1 - 2.4e-09 36.9 0.1 6.5e-09 35.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFQ95696.1 - 4.1e-07 29.7 0.0 7.8e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 KFQ95696.1 - 9.2e-06 25.1 0.0 1.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 F-box Pkinase_Tyr PF07714.17 KFQ95697.1 - 2.6e-98 328.5 0.0 3e-98 328.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ95697.1 - 7.6e-49 166.4 0.0 9.8e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.6 KFQ95697.1 - 3.5e-14 53.4 0.4 6.9e-14 52.5 0.4 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Haspin_kinase PF12330.8 KFQ95697.1 - 0.00055 19.0 0.0 0.004 16.2 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KFQ95697.1 - 0.097 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Auxin_inducible PF02519.14 KFQ95697.1 - 0.15 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Auxin responsive protein ABC1 PF03109.16 KFQ95697.1 - 0.18 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Pkinase_fungal PF17667.1 KFQ95697.1 - 0.2 10.4 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KFQ95697.1 - 0.24 11.0 0.6 2.3 7.8 0.1 2.5 2 1 0 3 3 3 0 RIO1 family HSP20 PF00011.21 KFQ95698.1 - 5.1e-16 58.7 0.5 7e-16 58.2 0.0 1.4 2 0 0 2 2 2 1 Hsp20/alpha crystallin family SPOC PF07744.13 KFQ95699.1 - 1.2e-24 86.9 0.1 1.4e-24 86.8 0.1 1.0 1 0 0 1 1 1 1 SPOC domain RRM_1 PF00076.22 KFQ95700.1 - 1.4e-24 85.6 1.3 4.7e-11 42.4 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFQ95700.1 - 0.00017 21.2 0.7 2.6 7.7 0.0 3.1 1 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFQ95700.1 - 0.074 13.2 0.0 16 5.7 0.0 3.0 3 0 0 3 3 3 0 RNA recognition motif AF-4 PF05110.13 KFQ95700.1 - 0.21 9.6 17.5 0.21 9.6 17.5 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Apt1 PF10351.9 KFQ95700.1 - 0.89 8.3 4.7 1 8.1 4.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain TMEM82 PF15816.5 KFQ95701.1 - 1.7e-120 401.7 14.6 1.8e-120 401.6 14.6 1.0 1 0 0 1 1 1 1 Transmembrane protein 82 PBP_N PF17093.5 KFQ95701.1 - 0.27 11.5 0.2 0.46 10.7 0.2 1.4 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus YfhO PF09586.10 KFQ95701.1 - 0.4 8.8 1.8 0.62 8.2 1.8 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Mito_carr PF00153.27 KFQ95702.1 - 7.5e-51 170.0 1.9 4.6e-16 58.5 0.4 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein UBA PF00627.31 KFQ95703.1 - 0.0002 21.2 0.1 0.00033 20.5 0.1 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Asp_protease PF09668.10 KFQ95704.1 - 1.8e-39 134.3 1.1 2.3e-39 134.0 1.1 1.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFQ95704.1 - 1.6e-17 63.8 0.0 5.1e-17 62.2 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KFQ95704.1 - 0.0022 17.7 0.1 0.0022 17.7 0.1 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KFQ95704.1 - 0.0066 17.1 0.0 0.019 15.6 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease DDOST_48kD PF03345.14 KFQ95705.1 - 1e-142 475.8 0.0 1.2e-142 475.7 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta OmpH PF03938.14 KFQ95706.1 - 0.0091 16.3 4.4 0.0091 16.3 4.4 2.1 1 1 1 2 2 2 1 Outer membrane protein (OmpH-like) BBP1_C PF15272.6 KFQ95706.1 - 0.061 13.1 15.6 0.26 11.1 14.6 2.0 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal DIT1_PvcA PF05141.12 KFQ95706.1 - 0.25 10.8 5.6 0.32 10.4 5.6 1.1 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein PRP1_N PF06424.12 KFQ95706.1 - 0.57 10.6 5.3 0.87 10.0 5.3 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal AAA_23 PF13476.6 KFQ95706.1 - 3.5 8.1 11.5 4.7 7.6 11.5 1.3 1 0 0 1 1 1 0 AAA domain IZUMO PF15005.6 KFQ95706.1 - 5.5 7.5 8.5 3.3 8.2 6.1 1.7 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated NBP1 PF08537.10 KFQ95706.1 - 6.4 6.1 14.5 3.1 7.1 12.1 1.6 1 1 1 2 2 2 0 Fungal Nap binding protein NBP1 Nop25 PF09805.9 KFQ95706.1 - 8.5 6.8 12.3 12 6.4 12.3 1.5 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) Antimicrobial23 PF16048.5 KFQ95707.1 - 0.24 11.1 1.6 0.54 10.0 1.6 1.6 1 0 0 1 1 1 0 Frog antimicrobial peptide Linker_histone PF00538.19 KFQ95708.1 - 2.1e-54 181.8 0.2 2.4e-18 66.3 0.0 3.4 3 0 0 3 3 3 3 linker histone H1 and H5 family YL1 PF05764.13 KFQ95708.1 - 0.00033 20.8 17.8 0.00033 20.8 17.8 2.6 2 1 0 2 2 1 1 YL1 nuclear protein BSP_II PF05432.11 KFQ95708.1 - 0.014 15.1 7.3 0.014 15.1 7.3 2.7 2 1 1 3 3 2 0 Bone sialoprotein II (BSP-II) SDA1 PF05285.12 KFQ95708.1 - 0.019 14.4 42.0 0.014 14.9 8.5 2.5 2 1 0 2 2 2 0 SDA1 RRN3 PF05327.11 KFQ95708.1 - 0.097 11.2 9.5 0.4 9.2 0.9 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 KFQ95708.1 - 0.11 10.8 31.7 0.064 11.6 13.9 2.3 2 0 0 2 2 2 0 CDC45-like protein Lin-8 PF03353.15 KFQ95708.1 - 0.43 10.1 22.7 0.67 9.5 7.1 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.12 KFQ95708.1 - 0.86 7.7 34.2 0.57 8.3 12.7 2.2 2 0 0 2 2 2 0 Nop14-like family DUF2052 PF09747.9 KFQ95708.1 - 5.4 7.1 35.1 1.6 8.8 14.5 2.7 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SpoIIIAH PF12685.7 KFQ95708.1 - 6.8 6.5 27.3 0.52 10.1 0.8 2.5 3 0 0 3 3 3 0 SpoIIIAH-like protein DUF913 PF06025.12 KFQ95708.1 - 9.1 5.1 16.7 1.2 8.1 2.5 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) MIF4G PF02854.19 KFQ95709.1 - 1.3e-68 230.9 8.5 2.6e-68 229.8 8.5 1.6 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 KFQ95709.1 - 6.1e-32 110.0 0.4 2.5e-31 108.0 0.1 2.3 2 0 0 2 2 2 1 MA3 domain W2 PF02020.18 KFQ95709.1 - 1.2e-18 67.0 4.4 3.1e-18 65.7 0.8 2.9 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon PP_kinase PF02503.17 KFQ95709.1 - 0.023 14.3 1.2 0.054 13.1 1.2 1.5 1 0 0 1 1 1 0 Polyphosphate kinase middle domain DUF1476 PF07345.11 KFQ95709.1 - 1.6 9.2 6.2 1.5 9.2 1.9 2.6 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta Peptidase_M13_N PF05649.13 KFQ95710.1 - 1.5e-125 419.8 1.2 1.9e-125 419.5 1.2 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFQ95710.1 - 2.5e-35 122.0 0.7 6.9e-35 120.5 0.2 2.0 2 0 0 2 2 2 1 Peptidase family M13 DUF3135 PF11333.8 KFQ95710.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) ImmE5 PF11480.8 KFQ95710.1 - 0.13 12.7 0.1 0.31 11.6 0.1 1.6 1 0 0 1 1 1 0 Colicin-E5 Imm protein Alk_phosphatase PF00245.20 KFQ95711.1 - 8.1e-110 367.6 0.0 9.2e-110 367.4 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase UCH PF00443.29 KFQ95713.1 - 2.3e-41 142.0 1.9 2.3e-41 142.0 1.9 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFQ95713.1 - 6.2e-22 78.6 3.0 6.2e-22 78.6 3.0 3.2 2 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KFQ95713.1 - 7.6e-11 42.5 0.4 5.8e-06 26.8 0.0 3.9 3 1 0 3 3 3 3 DUSP domain ubiquitin PF00240.23 KFQ95713.1 - 4.3e-05 23.2 0.1 0.00013 21.6 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family I-set PF07679.16 KFQ95714.1 - 2.1e-92 303.3 0.0 1e-13 51.1 0.0 8.5 8 0 0 8 8 8 8 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ95714.1 - 6.3e-88 289.5 7.2 2.6e-14 53.5 0.1 8.9 9 0 0 9 9 8 8 Immunoglobulin domain ig PF00047.25 KFQ95714.1 - 3.5e-59 197.0 0.0 1.3e-09 38.1 0.0 9.5 10 0 0 10 10 9 8 Immunoglobulin domain Ig_2 PF13895.6 KFQ95714.1 - 2.7e-58 194.2 0.1 2e-09 37.6 0.0 8.7 9 0 0 9 9 8 8 Immunoglobulin domain Laminin_G_1 PF00054.23 KFQ95714.1 - 2.5e-55 186.3 0.0 3.4e-28 98.5 0.0 2.6 2 0 0 2 2 2 2 Laminin G domain Laminin_G_2 PF02210.24 KFQ95714.1 - 3.2e-53 179.6 0.0 3.4e-26 92.3 0.0 3.0 3 0 0 3 3 3 2 Laminin G domain V-set PF07686.17 KFQ95714.1 - 3.2e-33 114.2 4.4 0.067 13.4 0.0 13.6 9 6 5 14 14 14 8 Immunoglobulin V-set domain EGF PF00008.27 KFQ95714.1 - 1e-20 73.6 50.3 1.8e-07 31.3 9.6 5.3 4 1 0 4 4 4 4 EGF-like domain Ig_6 PF18452.1 KFQ95714.1 - 2.6e-17 62.1 0.0 0.047 13.3 0.0 8.1 8 0 0 8 8 8 5 Immunoglobulin domain C2-set_2 PF08205.12 KFQ95714.1 - 6.7e-12 45.3 8.6 0.58 10.3 0.0 6.8 7 0 0 7 7 6 3 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFQ95714.1 - 5.2e-11 42.4 0.2 0.026 14.6 0.0 6.6 6 0 0 6 6 6 1 Izumo-like Immunoglobulin domain hEGF PF12661.7 KFQ95714.1 - 2.3e-07 31.2 42.3 0.0014 19.2 3.1 5.9 4 1 0 4 4 4 2 Human growth factor-like EGF Laminin_G_3 PF13385.6 KFQ95714.1 - 8.4e-07 29.3 0.0 0.0019 18.4 0.0 2.7 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Ig_C17orf99 PF17736.1 KFQ95714.1 - 2.1e-05 24.5 0.7 30 4.7 0.0 7.1 7 1 1 8 8 8 0 C17orf99 Ig domain C2-set PF05790.15 KFQ95714.1 - 0.00096 19.3 0.1 1.5 9.0 0.0 5.4 7 0 0 7 7 7 1 Immunoglobulin C2-set domain Herpes_gE PF02480.16 KFQ95714.1 - 0.023 13.5 0.3 1.1 7.9 0.0 3.5 4 1 0 5 5 5 0 Alphaherpesvirus glycoprotein E Receptor_2B4 PF11465.8 KFQ95714.1 - 0.12 12.6 0.0 1.9 8.7 0.0 2.8 3 0 0 3 3 3 0 Natural killer cell receptor 2B4 EGF_2 PF07974.13 KFQ95714.1 - 0.29 11.5 60.4 0.19 12.1 15.3 4.9 4 0 0 4 4 4 0 EGF-like domain Ig_3 PF13927.6 KFQ95715.1 - 6.2e-06 26.7 0.0 1e-05 26.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFQ95715.1 - 0.00019 21.7 0.0 0.0003 21.1 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ95715.1 - 0.00049 20.1 0.0 0.00067 19.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFQ95715.1 - 0.009 16.2 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFQ95715.1 - 0.039 14.1 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin V-set domain CCDC23 PF15674.5 KFQ95716.1 - 2.8e-31 107.3 10.0 3e-31 107.2 10.0 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 23 zf-C2H2 PF00096.26 KFQ95717.1 - 6.2e-14 51.6 23.3 2.3e-06 27.8 2.7 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ95717.1 - 4.2e-13 49.1 19.7 1.3e-07 31.7 1.2 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ95717.1 - 1e-10 41.5 22.6 0.00014 22.4 2.3 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ95717.1 - 2e-06 27.9 15.4 0.00048 20.3 0.5 3.2 2 1 1 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFQ95717.1 - 0.00011 22.5 19.2 0.0079 16.6 1.1 3.3 2 1 1 3 3 3 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KFQ95717.1 - 0.00028 20.7 0.6 0.00028 20.7 0.6 2.9 3 0 0 3 3 3 1 zinc-finger of a C2HC-type PyrI_C PF02748.15 KFQ95717.1 - 0.0081 16.0 1.9 0.13 12.2 0.1 2.3 2 0 0 2 2 2 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-AN1 PF01428.16 KFQ95717.1 - 0.0094 16.1 6.1 0.57 10.4 0.1 2.8 3 0 0 3 3 3 2 AN1-like Zinc finger zf-CHCC PF10276.9 KFQ95717.1 - 0.01 15.8 3.4 1.2 9.2 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger domain zf-Di19 PF05605.12 KFQ95717.1 - 0.02 15.2 12.2 0.024 14.9 4.2 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-trcl PF13451.6 KFQ95717.1 - 0.029 14.2 4.1 0.11 12.4 1.3 2.2 2 0 0 2 2 2 0 Probable zinc-ribbon domain zinc-ribbons_6 PF07191.12 KFQ95717.1 - 0.031 14.2 1.0 0.031 14.2 1.0 2.1 1 1 1 2 2 2 0 zinc-ribbons zf-C2H2_2 PF12756.7 KFQ95717.1 - 0.036 14.4 13.0 0.98 9.8 1.6 2.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) C1_1 PF00130.22 KFQ95717.1 - 0.04 13.8 9.4 0.25 11.2 4.9 2.9 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2HE PF16278.5 KFQ95717.1 - 0.099 13.1 15.3 0.43 11.1 2.5 2.5 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger FYDLN_acid PF09538.10 KFQ95717.1 - 0.16 12.7 1.3 16 6.2 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) PRP21_like_P PF12230.8 KFQ95717.1 - 0.17 11.8 1.1 0.16 11.8 1.1 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-C2H2_6 PF13912.6 KFQ95717.1 - 0.28 11.2 23.4 0.47 10.5 2.3 3.8 3 2 0 3 3 3 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFQ95717.1 - 0.55 10.4 11.3 1.9 8.6 4.6 2.3 2 1 0 2 2 2 0 Zinc ribbon domain zf-C2H2_9 PF16293.5 KFQ95717.1 - 0.69 9.8 7.3 0.56 10.1 0.2 2.7 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) XPA_N PF01286.18 KFQ95717.1 - 0.91 9.6 7.2 0.92 9.6 0.1 2.9 3 0 0 3 3 3 0 XPA protein N-terminal Zn_ribbon_SprT PF17283.2 KFQ95717.1 - 2.1 8.3 11.9 1.1 9.2 0.7 3.1 1 1 2 3 3 3 0 SprT-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 KFQ95717.1 - 3.5 7.7 9.7 0.08 12.9 3.1 1.7 2 0 0 2 2 2 0 Transposase zinc-ribbon domain FYVE PF01363.21 KFQ95717.1 - 4.3 7.5 10.1 39 4.5 10.1 2.4 1 1 0 1 1 1 0 FYVE zinc finger NADH-G_4Fe-4S_3 PF10588.9 KFQ95717.1 - 6.7 6.3 7.3 5.4 6.6 0.3 2.6 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Sugar_tr PF00083.24 KFQ95719.1 - 2.6e-156 521.0 24.2 3.2e-156 520.7 24.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFQ95719.1 - 4.3e-20 72.0 32.8 2.8e-18 66.0 26.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_EPC_I2-L1 PF12575.8 KFQ95719.1 - 0.29 11.4 3.2 1.3 9.3 3.2 2.2 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 Phage_holin_3_2 PF04550.12 KFQ95719.1 - 9 6.9 9.9 2 9.0 3.7 2.9 2 0 0 2 2 2 0 Phage holin family 2 TPR_12 PF13424.6 KFQ95720.1 - 2.8e-18 66.0 5.5 3.7e-05 23.9 0.4 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat zf-MYND PF01753.18 KFQ95720.1 - 9.4e-09 35.2 6.8 1.6e-08 34.5 6.8 1.4 1 0 0 1 1 1 1 MYND finger TPR_2 PF07719.17 KFQ95720.1 - 7.5e-07 28.8 10.7 0.028 14.5 0.4 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ95720.1 - 0.00035 20.3 4.2 0.077 12.9 0.1 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 KFQ95720.1 - 0.013 16.1 9.8 7 7.6 0.4 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ95720.1 - 0.035 13.9 8.4 7.9 6.5 0.2 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFQ95720.1 - 0.088 13.5 2.8 38 5.2 0.0 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ95720.1 - 0.26 11.6 1.8 34 5.0 0.2 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ95720.1 - 3.3 8.4 12.4 84 3.9 0.9 4.6 3 2 1 4 4 4 0 Tetratricopeptide repeat zf-HIT PF04438.16 KFQ95720.1 - 5.2 7.0 7.3 9.7 6.2 7.3 1.4 1 0 0 1 1 1 0 HIT zinc finger DFP PF04127.15 KFQ95721.1 - 3.3e-07 30.3 0.0 3.3e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein DUF4686 PF15742.5 KFQ95722.1 - 1.8e-99 333.5 96.6 1.8e-99 333.5 96.6 1.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4686) HU-CCDC81_euk_2 PF18289.1 KFQ95723.1 - 3.5e-19 68.7 0.0 4e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 Bac_DNA_binding PF00216.21 KFQ95723.1 - 0.083 13.1 0.0 0.12 12.6 0.0 1.3 1 1 0 1 1 1 0 Bacterial DNA-binding protein DUF134 PF02001.16 KFQ95723.1 - 0.085 13.4 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF134 CSD PF00313.22 KFQ95724.1 - 2.7e-14 52.8 0.1 4.7e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain PMP22_Claudin PF00822.20 KFQ95725.1 - 2.1e-16 60.3 6.3 2.5e-16 60.0 6.3 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFQ95725.1 - 4.8e-11 42.8 9.5 1.4e-10 41.3 9.5 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction FAM70 PF14967.6 KFQ95725.1 - 0.00082 18.9 0.1 0.0011 18.5 0.1 1.3 1 0 0 1 1 1 1 FAM70 protein Clc-like PF07062.12 KFQ95725.1 - 0.0026 17.3 0.4 0.0026 17.3 0.4 1.7 1 1 0 2 2 2 1 Clc-like L_HMGIC_fpl PF10242.9 KFQ95725.1 - 0.011 16.0 7.4 0.02 15.1 7.4 1.5 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.20 KFQ95726.1 - 3.5e-35 121.3 2.8 4.3e-35 121.0 2.8 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFQ95726.1 - 1.1e-11 44.9 6.6 5.7e-11 42.5 6.6 1.9 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction TMEM37 PF15108.6 KFQ95726.1 - 0.022 14.7 2.1 0.032 14.1 2.1 1.2 1 0 0 1 1 1 0 Voltage-dependent calcium channel gamma-like subunit protein family Amastin PF07344.11 KFQ95726.1 - 0.086 12.7 3.3 0.05 13.4 1.8 1.4 1 1 0 1 1 1 0 Amastin surface glycoprotein CD20 PF04103.15 KFQ95726.1 - 0.12 12.5 5.4 0.12 12.5 4.1 1.7 2 0 0 2 2 2 0 CD20-like family DUF1218 PF06749.12 KFQ95726.1 - 0.13 12.8 3.1 0.41 11.2 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) SK_channel PF03530.14 KFQ95726.1 - 0.13 12.3 0.4 0.19 11.7 0.4 1.2 1 0 0 1 1 1 0 Calcium-activated SK potassium channel Phage_holin_5_2 PF16079.5 KFQ95726.1 - 0.18 12.2 2.0 0.37 11.1 1.5 1.9 1 1 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V DUF2207 PF09972.9 KFQ95726.1 - 0.27 10.0 0.3 0.39 9.4 0.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4064 PF13273.6 KFQ95726.1 - 3.2 8.1 9.9 4.6 7.6 6.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF2721 PF11026.8 KFQ95726.1 - 3.3 7.6 6.4 0.18 11.7 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) 2OG-FeII_Oxy_3 PF13640.6 KFQ95727.1 - 4e-11 43.6 0.0 9.6e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KFQ95727.1 - 3.2e-09 37.2 0.0 6.5e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 KFQ95727.1 - 2.6e-05 24.0 7.5 0.0054 16.7 0.4 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ95727.1 - 0.00039 20.1 3.4 0.015 15.1 0.8 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ95727.1 - 0.0017 19.0 0.4 0.21 12.5 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ95727.1 - 0.0093 16.5 0.3 1.3 9.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ95727.1 - 0.047 13.9 0.6 0.36 11.2 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat 2OG-FeII_Oxy_4 PF13661.6 KFQ95727.1 - 0.061 14.0 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF2452 PF10504.9 KFQ95728.1 - 1.1e-58 197.2 0.1 1.2e-58 197.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2452) Ras PF00071.22 KFQ95729.1 - 2.9e-50 170.0 0.0 3.2e-50 169.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ95729.1 - 5.6e-20 71.7 0.0 7.7e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ95729.1 - 2.2e-06 27.3 0.0 2.4e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PET117 PF15786.5 KFQ95729.1 - 0.00047 20.4 0.0 0.00064 19.9 0.0 1.2 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial wnt PF00110.19 KFQ95730.1 - 5.4e-131 436.8 23.8 6.1e-131 436.6 23.8 1.0 1 0 0 1 1 1 1 wnt family Pkinase_Tyr PF07714.17 KFQ95731.1 - 7.6e-94 313.8 0.0 1e-93 313.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.19 KFQ95731.1 - 4.5e-67 225.5 0.0 6.9e-67 224.9 0.0 1.3 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.25 KFQ95731.1 - 1.3e-45 155.9 0.0 1.8e-45 155.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 KFQ95731.1 - 4.1e-31 107.2 0.1 1.1e-15 57.7 0.1 2.9 3 0 0 3 3 3 2 Fibronectin type III domain EphA2_TM PF14575.6 KFQ95731.1 - 7.4e-21 74.8 0.0 1.6e-20 73.7 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SAM_1 PF00536.30 KFQ95731.1 - 1.5e-19 70.2 0.1 2.6e-19 69.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFQ95731.1 - 1.4e-15 57.1 0.0 3.1e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pur_ac_phosph_N PF16656.5 KFQ95731.1 - 8.1e-08 32.7 0.2 2.6e-06 27.9 0.3 2.5 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.5 KFQ95731.1 - 1.1e-06 28.7 0.4 0.0008 19.5 0.1 2.5 2 0 0 2 2 2 2 Fibronectin type III domain SusE PF14292.6 KFQ95731.1 - 6.2e-06 26.4 0.0 0.0073 16.5 0.2 2.4 2 0 0 2 2 2 2 SusE outer membrane protein Ephrin_rec_like PF07699.13 KFQ95731.1 - 0.00012 21.7 5.7 0.00015 21.4 2.5 2.5 2 0 0 2 2 2 1 Putative ephrin-receptor like DUF2369 PF10179.9 KFQ95731.1 - 0.0017 18.7 0.0 0.33 11.4 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2369) Kdo PF06293.14 KFQ95731.1 - 0.005 16.2 0.0 0.0089 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Interfer-bind PF09294.10 KFQ95731.1 - 0.0079 16.5 0.1 0.059 13.7 0.1 2.4 3 0 0 3 3 2 1 Interferon-alpha/beta receptor, fibronectin type III Haspin_kinase PF12330.8 KFQ95731.1 - 0.0095 14.9 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain DUF3300 PF11737.8 KFQ95731.1 - 0.12 11.9 2.1 3.2 7.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3300) C1q PF00386.21 KFQ95732.1 - 5e-34 117.2 0.0 6.1e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFQ95732.1 - 6.6e-13 48.2 31.0 1.3e-08 34.4 16.9 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) BclA_C PF18573.1 KFQ95732.1 - 0.14 12.1 0.3 0.29 11.1 0.3 1.5 1 1 0 1 1 1 0 BclA C-terminal domain Collagen PF01391.18 KFQ95733.1 - 2.8e-19 68.6 53.7 1.7e-10 40.5 22.4 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) C1q PF00386.21 KFQ95733.1 - 3.2e-17 62.9 0.2 3.9e-17 62.7 0.2 1.1 1 0 0 1 1 1 1 C1q domain Pkinase_Tyr PF07714.17 KFQ95734.1 - 3.1e-99 331.4 0.0 3.6e-99 331.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ95734.1 - 2e-49 168.4 0.0 2.4e-49 168.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.6 KFQ95734.1 - 1.5e-13 51.4 1.0 2.6e-13 50.6 1.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Haspin_kinase PF12330.8 KFQ95734.1 - 0.008 15.2 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFQ95734.1 - 0.022 14.1 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFQ95734.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Beta-lactamase PF00144.24 KFQ95735.1 - 4.2e-37 128.1 0.0 6.3e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase FTO_CTD PF12934.7 KFQ95736.1 - 1.9e-09 37.5 0.3 2e-09 37.4 0.3 1.0 1 0 0 1 1 1 1 FTO C-terminal domain FTO_NTD PF12933.7 KFQ95737.1 - 4.4e-123 410.1 0.0 5.8e-123 409.7 0.0 1.1 1 0 0 1 1 1 1 FTO catalytic domain FTO_CTD PF12934.7 KFQ95737.1 - 1.2e-40 139.0 7.6 2.1e-40 138.2 7.6 1.4 1 0 0 1 1 1 1 FTO C-terminal domain C2-C2_1 PF11618.8 KFQ95738.1 - 2.4e-68 228.6 8.5 1.5e-57 193.6 0.4 4.8 4 1 0 4 4 4 3 First C2 domain of RPGR-interacting protein 1 RPGR1_C PF18111.1 KFQ95738.1 - 8.2e-59 198.2 1.4 5e-58 195.6 0.4 2.7 2 0 0 2 2 2 1 Retinitis pigmentosa G-protein regulator interacting C-terminal C2 PF00168.30 KFQ95738.1 - 6.8e-07 29.5 0.2 7e-06 26.3 0.0 2.8 2 1 1 3 3 3 1 C2 domain DUF4497 PF14924.6 KFQ95738.1 - 0.55 10.7 7.6 19 5.8 0.0 5.1 6 0 0 6 6 6 0 Protein of unknown function (DUF4497) UQ_con PF00179.26 KFQ95739.1 - 7.8e-23 80.7 0.0 1.4e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RB_A PF01858.17 KFQ95740.1 - 6e-73 244.9 0.9 1.8e-71 240.1 0.3 2.5 2 0 0 2 2 2 1 Retinoblastoma-associated protein A domain RB_B PF01857.20 KFQ95740.1 - 3.9e-58 195.2 0.2 1.8e-57 193.1 0.0 2.3 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 KFQ95740.1 - 2e-48 163.4 0.1 2e-48 163.4 0.1 3.1 5 0 0 5 5 5 1 Domain of unknown function (DUF3452) Imm-NTF2 PF15655.6 KFQ95740.1 - 0.1 12.9 0.5 0.26 11.6 0.2 1.8 2 0 0 2 2 2 0 NTF2 fold immunity protein SNF2_N PF00176.23 KFQ95742.1 - 1.3e-59 201.7 0.4 2.5e-59 200.8 0.4 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain BRK PF07533.16 KFQ95742.1 - 9.9e-34 114.7 0.1 1.7e-16 59.5 0.1 2.7 2 0 0 2 2 2 2 BRK domain Chromo PF00385.24 KFQ95742.1 - 4.9e-23 80.8 8.7 8.5e-12 44.8 2.1 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KFQ95742.1 - 4.6e-17 62.4 0.0 2.2e-16 60.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFQ95742.1 - 3.9e-07 30.2 0.0 1.3e-06 28.6 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CHDCT2 PF08074.11 KFQ95742.1 - 3.1e-05 24.2 0.0 0.44 10.7 0.0 3.6 3 0 0 3 3 3 2 CHDCT2 (NUC038) domain DEAD PF00270.29 KFQ95742.1 - 0.00031 20.6 0.0 0.00067 19.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KFQ95742.1 - 0.019 14.2 0.1 0.019 14.2 0.1 2.5 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Myb_DNA-bind_7 PF15963.5 KFQ95742.1 - 0.052 13.5 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 Myb DNA-binding like cIII PF08134.11 KFQ95742.1 - 0.15 11.8 0.1 0.38 10.5 0.1 1.7 1 0 0 1 1 1 0 cIII protein family DUF4179 PF13786.6 KFQ95742.1 - 0.21 12.1 0.1 0.57 10.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) HMG_box PF00505.19 KFQ95743.1 - 6.1e-18 65.0 0.3 1.8e-17 63.5 0.3 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFQ95743.1 - 7.8e-12 45.6 0.5 7.8e-12 45.6 0.5 2.6 2 1 0 2 2 2 1 HMG-box domain PA-IL PF07828.12 KFQ95743.1 - 0.068 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 PA-IL-like protein IMUP PF15761.5 KFQ95743.1 - 0.19 12.5 12.0 0.11 13.2 8.5 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein zf-C2H2_4 PF13894.6 KFQ95746.1 - 3.5e-34 114.5 73.2 8.7e-05 23.0 0.4 10.6 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2H2 PF00096.26 KFQ95746.1 - 6.6e-34 114.5 73.8 1.4e-05 25.2 0.2 10.1 10 0 0 10 10 9 8 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFQ95746.1 - 1.4e-25 89.0 39.5 0.00017 21.7 1.4 9.4 9 0 0 9 9 9 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFQ95746.1 - 4.3e-25 87.3 52.2 0.001 19.4 0.6 9.8 9 0 0 9 9 9 8 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KFQ95746.1 - 1.6e-22 78.9 74.4 4.9e-07 29.9 1.1 11.9 13 0 0 13 13 12 5 Zinc-finger double domain zf-C2H2_6 PF13912.6 KFQ95746.1 - 1.4e-08 34.5 68.7 0.12 12.4 2.0 10.2 10 0 0 10 10 10 7 C2H2-type zinc finger IZUMO PF15005.6 KFQ95746.1 - 0.0014 19.2 0.4 0.19 12.2 0.0 2.8 2 0 0 2 2 2 1 Izumo sperm-egg fusion, Ig domain-associated BolA PF01722.18 KFQ95746.1 - 0.01 16.1 9.9 1.9 8.8 0.0 5.1 5 0 0 5 5 5 0 BolA-like protein DUF3268 PF11672.8 KFQ95746.1 - 0.01 16.2 17.3 0.39 11.1 0.3 4.4 4 0 0 4 4 4 0 zinc-finger-containing domain zf-C2H2_2 PF12756.7 KFQ95746.1 - 0.013 15.8 45.8 1.1 9.6 0.9 9.2 5 4 5 10 10 10 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KFQ95746.1 - 0.032 14.1 5.4 7.7 6.4 0.2 4.9 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 KFQ95746.1 - 0.067 13.5 41.0 0.035 14.4 2.3 5.4 6 0 0 6 6 5 0 Drought induced 19 protein (Di19), zinc-binding Hexapep PF00132.24 KFQ95746.1 - 0.12 12.1 0.2 0.35 10.7 0.2 1.7 1 0 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) zf-C2HC_2 PF13913.6 KFQ95746.1 - 0.2 11.6 44.6 0.58 10.1 0.1 8.3 9 0 0 9 9 8 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KFQ95746.1 - 0.25 11.1 50.1 0.67 9.8 0.0 8.7 9 0 0 9 9 8 0 zinc-finger C2H2-type zf-C2HE PF16278.5 KFQ95746.1 - 6 7.4 41.6 0.3 11.6 1.0 7.1 6 2 0 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2HC_14 PF18574.1 KFQ95746.1 - 10 6.0 7.3 2.5 7.9 2.1 2.8 2 0 0 2 2 2 0 C2HC Zing finger domain PX PF00787.24 KFQ95747.1 - 2.2e-16 59.8 6.6 3.2e-16 59.3 4.0 2.4 3 0 0 3 3 3 1 PX domain TPR_12 PF13424.6 KFQ95747.1 - 0.0017 18.6 0.0 0.0032 17.7 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ95747.1 - 0.0067 16.5 0.0 0.63 10.4 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ95747.1 - 0.15 12.0 0.2 28 4.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Ocnus PF05005.15 KFQ95747.1 - 0.16 12.1 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Janus/Ocnus family (Ocnus) TPR_2 PF07719.17 KFQ95747.1 - 0.42 10.8 1.8 16 5.9 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat EF-hand_7 PF13499.6 KFQ95748.1 - 0.0012 19.3 0.0 0.0036 17.7 0.0 2.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFQ95748.1 - 0.0028 17.5 0.0 0.0065 16.3 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KFQ95748.1 - 0.0097 15.4 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 EF hand Nitroreductase PF00881.24 KFQ95748.1 - 0.018 15.1 0.3 0.16 12.0 0.0 2.2 2 1 0 2 2 2 0 Nitroreductase family DUF3512 PF12024.8 KFQ95751.1 - 2.1e-86 289.3 0.1 2.1e-86 289.3 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3512) Bromodomain PF00439.25 KFQ95751.1 - 9e-22 76.9 1.6 2.2e-21 75.7 1.6 1.7 1 0 0 1 1 1 1 Bromodomain Vfa1 PF08432.10 KFQ95751.1 - 4.5 7.6 23.2 0.2 12.0 5.2 2.6 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 DUF2796 PF10986.8 KFQ95751.1 - 5.1 7.0 11.1 0.22 11.5 4.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) NTP_transf_2 PF01909.23 KFQ95752.1 - 1.8e-16 60.2 0.1 4.4e-16 58.9 0.1 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 KFQ95752.1 - 4.8e-15 55.5 0.1 1.5e-14 53.9 0.0 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase Polbeta PF18765.1 KFQ95752.1 - 0.00052 20.0 0.0 0.0013 18.8 0.0 1.8 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase HEAT_EZ PF13513.6 KFQ95753.1 - 2.1e-09 37.7 1.1 2.9e-05 24.5 0.1 4.5 4 1 0 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.6 KFQ95753.1 - 6e-06 26.6 0.4 0.0094 16.3 0.0 3.5 2 1 0 2 2 2 2 HEAT repeats HEAT PF02985.22 KFQ95753.1 - 1.2e-05 25.2 8.4 0.43 11.0 0.2 5.6 5 0 0 5 5 5 2 HEAT repeat Arm PF00514.23 KFQ95753.1 - 0.0058 16.6 0.1 0.0058 16.6 0.1 5.7 9 0 0 9 9 9 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KFQ95753.1 - 0.015 15.3 0.5 0.19 11.8 0.5 2.7 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 TAF6_C PF07571.13 KFQ95753.1 - 0.027 14.8 0.0 0.13 12.6 0.0 2.3 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain Flt3_lig PF02947.14 KFQ95753.1 - 0.26 11.5 3.8 7.6 6.7 0.1 3.5 3 0 0 3 3 3 0 flt3 ligand Tmemb_18A PF09771.9 KFQ95754.1 - 2.8e-56 189.0 0.1 3.1e-56 188.9 0.1 1.0 1 0 0 1 1 1 1 Transmembrane protein 188 DUF418 PF04235.12 KFQ95754.1 - 0.029 14.3 0.2 0.032 14.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF418) DUF35_N PF12172.8 KFQ95754.1 - 0.1 12.5 0.0 6.3 6.8 0.0 3.1 4 0 0 4 4 4 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF5392 PF17370.2 KFQ95754.1 - 0.19 11.8 0.1 0.23 11.5 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5392) zf-C2H2_4 PF13894.6 KFQ95756.1 - 3e-69 223.6 216.0 0.00039 21.0 1.7 31.2 31 0 0 31 31 31 28 C2H2-type zinc finger zf-C2H2 PF00096.26 KFQ95756.1 - 2.9e-58 191.2 215.6 0.00032 21.0 1.4 30.9 31 0 0 31 31 31 22 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ95756.1 - 3.1e-26 90.6 186.3 0.00029 21.1 2.9 29.9 30 0 0 30 30 30 14 Zinc-finger double domain zf-Di19 PF05605.12 KFQ95756.1 - 3.3e-23 81.7 186.7 0.00028 21.1 2.6 19.8 17 4 6 23 23 23 13 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KFQ95756.1 - 7.1e-22 76.9 169.5 1.5e-05 24.8 0.9 26.3 26 1 1 27 27 27 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ95756.1 - 1.9e-17 63.0 171.1 0.0098 16.2 0.8 27.3 27 2 1 28 28 28 13 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 KFQ95756.1 - 6.6e-05 23.6 114.4 0.0013 19.4 8.0 17.0 8 5 6 14 14 14 4 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 KFQ95756.1 - 0.00037 20.8 15.8 0.0024 18.2 2.1 22.9 28 0 0 28 28 27 8 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFQ95756.1 - 0.00072 19.8 177.2 0.67 10.3 6.0 24.7 7 5 11 19 19 18 7 C2H2 type zinc-finger (2 copies) C1_4 PF07975.12 KFQ95756.1 - 0.029 14.6 0.8 0.029 14.6 0.8 19.5 14 3 9 24 24 23 0 TFIIH C1-like domain Zf_RING PF16744.5 KFQ95756.1 - 0.029 14.5 0.6 0.029 14.5 0.6 12.7 12 4 5 17 17 17 0 KIAA1045 RING finger zf-C2H2_9 PF16293.5 KFQ95756.1 - 0.09 12.6 0.1 0.09 12.6 0.1 17.4 17 4 4 21 21 21 0 C2H2 type zinc-finger (1 copy) Zn-C2H2_12 PF18112.1 KFQ95756.1 - 0.11 13.0 0.2 0.11 13.0 0.2 14.4 15 0 0 15 15 13 0 Autophagy receptor zinc finger-C2H2 domain zf-C2HE PF16278.5 KFQ95756.1 - 0.31 11.5 0.0 0.11 12.9 0.6 21.6 14 5 9 23 23 21 0 C2HE / C2H2 / C2HC zinc-binding finger RNase_Zc3h12a PF11977.8 KFQ95757.1 - 3.8e-55 185.9 0.0 1.4e-54 184.1 0.0 2.0 2 0 0 2 2 2 1 Zc3h12a-like Ribonuclease NYN domain DUF4392 PF14336.6 KFQ95757.1 - 0.0013 18.2 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) UBA_6 PF18039.1 KFQ95757.1 - 0.002 18.0 0.4 0.0064 16.4 0.0 2.1 2 0 0 2 2 2 1 UBA-like domain Sina PF03145.16 KFQ95758.1 - 2.7e-88 295.2 0.1 4e-88 294.6 0.1 1.2 1 0 0 1 1 1 1 Seven in absentia protein family Lon_C PF05362.13 KFQ95759.1 - 1.4e-79 266.4 0.0 2.3e-79 265.7 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 KFQ95759.1 - 1e-21 77.8 0.0 3.3e-21 76.1 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 KFQ95759.1 - 2.3e-15 57.0 0.2 2.3e-15 57.0 0.2 1.8 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA_5 PF07728.14 KFQ95759.1 - 5.6e-09 36.1 0.0 1.4e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFQ95759.1 - 5.8e-05 23.5 0.2 0.00049 20.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain ChlI PF13541.6 KFQ95759.1 - 7.9e-05 22.5 0.0 0.00019 21.3 0.0 1.7 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_3 PF07726.11 KFQ95759.1 - 0.00054 19.8 0.0 0.0014 18.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFQ95759.1 - 0.0017 18.7 0.1 0.026 14.8 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.11 KFQ95759.1 - 0.0018 17.3 0.0 0.018 14.0 0.0 2.1 2 0 0 2 2 2 1 PrkA AAA domain AAA_2 PF07724.14 KFQ95759.1 - 0.004 17.3 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RsgA_GTPase PF03193.16 KFQ95759.1 - 0.0051 16.7 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 KFQ95759.1 - 0.0066 17.0 0.0 0.026 15.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KFQ95759.1 - 0.01 15.6 0.0 0.038 13.7 0.0 1.9 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KFQ95759.1 - 0.025 14.3 0.1 0.077 12.7 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.15 KFQ95759.1 - 0.029 14.3 0.0 0.064 13.2 0.0 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain SKI PF01202.22 KFQ95759.1 - 0.036 14.2 0.6 0.089 12.9 0.0 1.9 2 0 0 2 2 2 0 Shikimate kinase AAA_33 PF13671.6 KFQ95759.1 - 0.06 13.5 0.4 0.27 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFQ95759.1 - 0.14 12.5 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Sld5 PF05916.11 KFQ95759.1 - 0.49 10.9 7.3 1.4 9.4 0.6 2.5 2 0 0 2 2 2 0 GINS complex protein DUF4375 PF14300.6 KFQ95759.1 - 0.95 9.7 2.8 0.96 9.7 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Glyco_hydro_15 PF00723.21 KFQ95761.1 - 2.9e-108 362.5 0.0 5.9e-108 361.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 VCBS PF13517.6 KFQ95762.1 - 4.9e-18 65.5 9.5 3.2e-05 24.4 2.0 5.4 4 1 1 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KFQ95762.1 - 4.4e-08 33.1 10.2 0.041 14.0 0.1 5.6 6 0 0 6 6 6 3 FG-GAP repeat Phage_holin_2_4 PF16082.5 KFQ95762.1 - 0.14 11.9 0.1 0.28 11.0 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like K1 PF02960.14 KFQ95762.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 K1 glycoprotein CUB PF00431.20 KFQ95763.1 - 1.7e-41 141.0 0.2 1.2e-26 93.2 0.0 3.0 3 0 0 3 3 3 2 CUB domain Ldl_recept_a PF00057.18 KFQ95763.1 - 1.5e-06 28.3 3.4 1.5e-06 28.3 3.4 2.5 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A Arm_vescicular PF18770.1 KFQ95763.1 - 0.067 13.1 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Armadillo tether-repeat of vescicular transport factor DnaJ_C PF01556.18 KFQ95764.1 - 9.9e-45 152.3 0.2 1.2e-44 151.9 0.2 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFQ95764.1 - 4.1e-16 58.9 1.0 7.6e-16 58.0 1.0 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KFQ95764.1 - 1e-14 54.6 17.4 1.8e-14 53.8 17.4 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KFQ95764.1 - 0.23 11.5 19.3 0.17 11.9 3.2 2.9 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KFQ95764.1 - 0.76 9.8 11.6 2.4 8.2 3.4 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.5 KFQ95764.1 - 2.7 8.2 5.1 3.8 7.7 0.6 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 DUF1258 PF06869.12 KFQ95764.1 - 3 7.3 11.5 0.58 9.6 2.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) A2L_zn_ribbon PF08792.10 KFQ95764.1 - 5.4 6.8 18.2 1.6 8.6 5.5 3.8 3 1 1 4 4 4 0 A2L zinc ribbon domain Borealin PF10512.9 KFQ95765.1 - 1.2e-09 38.2 0.0 1.3e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Cell division cycle-associated protein 8 Marek_A PF02124.15 KFQ95765.1 - 0.085 12.7 0.0 0.085 12.7 0.0 1.0 1 0 0 1 1 1 0 Marek's disease glycoprotein A Aminotran_1_2 PF00155.21 KFQ95766.1 - 1e-31 110.4 0.0 1.2e-31 110.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II UPF0547 PF10571.9 KFQ95767.1 - 1.8e-05 24.7 2.8 2.7e-05 24.1 2.8 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 Zip PF02535.22 KFQ95767.1 - 0.34 10.1 2.7 0.39 9.9 2.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Sec62 PF03839.16 KFQ95767.1 - 0.38 10.2 4.4 0.42 10.1 4.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 RAM PF15320.6 KFQ95767.1 - 0.62 10.7 8.4 0.96 10.1 8.4 1.2 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein Presenilin PF01080.17 KFQ95767.1 - 0.93 8.2 6.3 1.1 8.0 6.3 1.0 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 KFQ95767.1 - 1.8 8.5 4.9 2.2 8.3 4.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.7 KFQ95767.1 - 4 5.5 7.8 4.6 5.2 7.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 KFQ95767.1 - 9.5 4.4 10.9 11 4.2 10.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 KFQ95768.1 - 5.2e-21 75.2 0.0 6.1e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ95768.1 - 1.9e-05 24.1 0.0 2.6e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase ORC6 PF05460.13 KFQ95769.1 - 4.2e-12 46.0 11.4 1.9e-09 37.3 1.8 2.9 2 1 0 2 2 2 2 Origin recognition complex subunit 6 (ORC6) Vps35 PF03635.17 KFQ95770.1 - 1.2e-301 1002.7 13.1 1.4e-301 1002.5 13.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 FerA PF08165.11 KFQ95770.1 - 0.022 14.7 0.2 0.12 12.4 0.2 2.2 1 0 0 1 1 1 0 FerA (NUC095) domain 7tm_1 PF00001.21 KFQ95771.1 - 1.3e-62 211.5 5.2 1.6e-62 211.2 5.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ95771.1 - 1.6e-07 31.0 12.1 7.6e-05 22.2 5.0 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFQ95771.1 - 0.0064 16.3 3.1 0.0064 16.3 3.1 2.1 2 0 0 2 2 2 1 Olfactory receptor DUF996 PF06195.13 KFQ95771.1 - 1.7 8.9 10.4 0.2 11.9 2.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF996) Beta_helix PF13229.6 KFQ95772.1 - 9.8e-11 41.8 0.9 2.1e-10 40.7 0.9 1.5 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 KFQ95772.1 - 1.2e-07 31.3 0.1 2.4e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 KFQ95772.1 - 0.0028 17.5 0.6 0.063 13.1 0.6 2.2 1 1 0 1 1 1 1 Pectate lyase superfamily protein UCR_TM PF02921.14 KFQ95773.1 - 7.2e-27 93.7 3.5 1e-26 93.1 3.5 1.2 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 KFQ95773.1 - 4.6e-13 48.9 0.1 1.2e-12 47.6 0.1 1.7 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Isochorismatase PF00857.20 KFQ95773.1 - 0.062 13.5 0.1 2.4 8.3 0.1 2.1 1 1 0 1 1 1 0 Isochorismatase family Oxidored_q6 PF01058.22 KFQ95773.1 - 0.1 12.4 0.0 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase, 20 Kd subunit V-set PF07686.17 KFQ95775.1 - 0.00028 21.0 0.0 0.00034 20.8 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFQ95775.1 - 0.0087 16.1 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ95775.1 - 0.025 15.1 0.0 0.033 14.8 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain UPF0086 PF01868.16 KFQ95776.1 - 2.8e-26 91.3 0.1 2.8e-26 91.3 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function UPF0086 FYVE PF01363.21 KFQ95777.1 - 5.8e-18 64.8 7.1 1.2e-17 63.8 7.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 KFQ95777.1 - 5.5e-09 36.5 0.4 1.1e-08 35.5 0.2 1.6 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 KFQ95777.1 - 0.00015 21.6 0.5 0.0052 16.6 0.5 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 KFQ95777.1 - 0.00055 19.9 0.1 0.0011 19.0 0.1 1.4 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.16 KFQ95777.1 - 0.0097 16.1 8.9 0.016 15.4 8.5 1.6 1 1 0 1 1 1 1 FYVE-type zinc finger C1_2 PF03107.16 KFQ95777.1 - 0.032 14.6 4.0 0.053 13.9 2.2 2.1 2 0 0 2 2 2 0 C1 domain DUF1835 PF08874.10 KFQ95777.1 - 0.036 14.3 0.0 0.072 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) PH_6 PF15406.6 KFQ95777.1 - 0.045 14.1 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain tRNA_bind_3 PF17176.4 KFQ95777.1 - 0.094 13.0 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 tRNA-binding domain OrfB_Zn_ribbon PF07282.11 KFQ95777.1 - 1.6 8.7 6.8 3.9 7.5 6.8 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Bacteriocin_IIc PF10439.9 KFQ95778.1 - 1.7 8.8 12.4 2.5 8.3 12.4 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.6 KFQ95778.1 - 3 7.9 19.0 18 5.4 19.0 2.0 1 1 1 2 2 2 0 Glycine zipper Gly-zipper_YMGG PF13441.6 KFQ95778.1 - 4.4 7.1 18.2 9 6.1 18.2 1.5 1 1 0 1 1 1 0 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.9 KFQ95779.1 - 1.7 8.8 12.4 2.6 8.2 12.4 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.6 KFQ95779.1 - 3.4 7.7 19.1 21 5.2 19.2 2.0 1 1 1 2 2 2 0 Glycine zipper Gly-zipper_YMGG PF13441.6 KFQ95779.1 - 4.2 7.2 18.2 9.2 6.1 18.2 1.6 1 1 0 1 1 1 0 YMGG-like Gly-zipper PLA2_B PF01735.18 KFQ95780.1 - 1.7e-158 528.1 0.0 2.1e-158 527.8 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain C2 PF00168.30 KFQ95780.1 - 2.4e-15 56.7 0.1 4.9e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 C2 domain DUF2281 PF10047.9 KFQ95780.1 - 0.058 14.1 0.0 0.16 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) An_peroxidase PF03098.15 KFQ95781.1 - 1.9e-55 188.5 0.0 6.4e-49 166.9 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase EGF PF00008.27 KFQ95781.1 - 3e-05 24.2 13.8 6.3e-05 23.2 13.8 1.6 1 0 0 1 1 1 1 EGF-like domain Phosducin PF02114.16 KFQ95782.1 - 2.4e-113 377.5 2.1 2.5e-113 377.4 2.1 1.0 1 0 0 1 1 1 1 Phosducin ODR4-like PF14778.6 KFQ95783.1 - 7.3e-117 390.4 1.0 9.8e-117 390.0 1.0 1.2 1 0 0 1 1 1 1 Olfactory receptor 4-like TPR_MLP1_2 PF07926.12 KFQ95784.1 - 3.9e-33 114.3 31.5 3.9e-33 114.3 31.5 16.1 7 4 6 15 15 15 10 TPR/MLP1/MLP2-like protein ERM PF00769.19 KFQ95784.1 - 0.0025 17.7 34.9 0.0025 17.7 34.9 11.7 5 2 7 12 12 12 2 Ezrin/radixin/moesin family I-set PF07679.16 KFQ95785.1 - 0 2252.3 0.0 3.3e-20 72.0 0.2 44.3 44 0 0 44 44 44 44 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ95785.1 - 0 2008.3 79.8 1e-16 61.3 0.2 44.6 44 0 0 44 44 44 44 Immunoglobulin domain Ig_2 PF13895.6 KFQ95785.1 - 0 1387.5 49.8 4.2e-11 43.0 0.1 44.8 45 0 0 45 45 44 42 Immunoglobulin domain ig PF00047.25 KFQ95785.1 - 0 1144.8 0.1 4.8e-11 42.7 0.0 45.0 44 0 0 44 44 44 42 Immunoglobulin domain V-set PF07686.17 KFQ95785.1 - 6.6e-135 441.4 99.2 0.0068 16.6 0.0 68.9 48 30 5 53 53 52 32 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFQ95785.1 - 3.3e-105 344.4 43.4 0.023 14.7 0.0 40.4 41 0 0 41 41 41 24 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFQ95785.1 - 2.6e-98 321.5 2.8 0.08 12.5 0.0 43.1 46 0 0 46 46 44 22 Immunoglobulin domain Ig_5 PF16681.5 KFQ95785.1 - 8.6e-80 263.2 0.0 0.038 14.4 0.0 39.5 44 0 0 44 44 42 10 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain EGF_CA PF07645.15 KFQ95785.1 - 6.3e-63 208.7 119.2 1.1e-12 47.9 7.0 10.0 9 0 0 9 9 8 8 Calcium-binding EGF domain Ig_4 PF16680.5 KFQ95785.1 - 3.3e-58 193.9 0.0 0.17 12.2 0.0 35.7 40 0 0 40 40 39 8 T-cell surface glycoprotein CD3 delta chain G2F PF07474.12 KFQ95785.1 - 6e-54 182.6 0.0 1.2e-53 181.6 0.0 1.6 1 0 0 1 1 1 1 G2F domain TSP_1 PF00090.19 KFQ95785.1 - 6e-52 173.6 146.9 9.8e-13 48.1 7.4 8.8 10 0 0 10 10 6 6 Thrombospondin type 1 domain cEGF PF12662.7 KFQ95785.1 - 4e-47 157.7 64.0 2.3e-11 43.4 1.2 10.4 9 0 0 9 9 9 8 Complement Clr-like EGF-like Izumo-Ig PF16706.5 KFQ95785.1 - 2e-37 127.1 12.2 1.3 9.1 0.0 32.9 39 0 0 39 39 37 4 Izumo-like Immunoglobulin domain C1-set PF07654.15 KFQ95785.1 - 9.5e-30 102.8 8.2 0.29 11.5 0.0 26.6 32 0 0 32 32 30 2 Immunoglobulin C1-set domain Receptor_2B4 PF11465.8 KFQ95785.1 - 4.3e-29 100.9 9.2 0.5 10.6 0.0 25.4 29 2 1 30 30 27 3 Natural killer cell receptor 2B4 Ig_C17orf99 PF17736.1 KFQ95785.1 - 3.2e-24 84.8 21.2 5.5 7.1 0.0 28.4 35 0 0 35 35 32 1 C17orf99 Ig domain C2-set PF05790.15 KFQ95785.1 - 4.2e-17 62.1 3.3 4.4 7.6 0.1 20.4 28 0 0 28 28 22 1 Immunoglobulin C2-set domain FXa_inhibition PF14670.6 KFQ95785.1 - 7.6e-11 42.1 40.8 8.8e-08 32.3 8.0 10.7 12 0 0 12 12 8 6 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 KFQ95785.1 - 2.3e-06 27.7 110.2 0.00023 21.3 7.8 9.6 9 0 0 9 9 8 5 EGF domain EGF PF00008.27 KFQ95785.1 - 0.0019 18.4 7.3 0.0019 18.4 7.3 10.9 9 1 1 10 10 8 4 EGF-like domain ANAPC4_WD40 PF12894.7 KFQ95785.1 - 0.024 14.9 0.0 5.5 7.4 0.0 4.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Herpes_gI PF01688.17 KFQ95785.1 - 0.025 14.5 2.7 78 3.1 0.0 8.3 15 0 0 15 15 11 0 Alphaherpesvirus glycoprotein I Peptidase_S9_N PF02897.15 KFQ95785.1 - 0.099 11.4 0.1 1.1e+02 1.4 0.0 5.0 6 0 0 6 6 6 0 Prolyl oligopeptidase, N-terminal beta-propeller domain hEGF PF12661.7 KFQ95785.1 - 1.9 9.3 87.2 0.077 13.7 5.2 12.2 9 0 0 9 9 8 0 Human growth factor-like EGF Kelch_1 PF01344.25 KFQ95789.1 - 1.4e-86 283.9 12.3 2.3e-15 55.9 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFQ95789.1 - 4.3e-49 163.3 2.8 2.4e-10 40.3 0.0 6.5 1 1 5 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KFQ95789.1 - 1.2e-38 130.7 7.2 1.6e-08 34.6 0.2 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 KFQ95789.1 - 5.7e-37 124.3 1.9 8e-05 22.5 0.0 6.8 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 KFQ95789.1 - 8.3e-34 115.4 2.5 9.9e-07 28.7 0.0 6.1 5 1 1 6 6 6 5 Galactose oxidase, central domain BTB PF00651.31 KFQ95789.1 - 9.4e-27 93.4 0.5 1.4e-26 92.9 0.5 1.3 1 0 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.6 KFQ95789.1 - 2.3e-16 59.4 5.1 0.0021 18.0 0.0 6.1 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 KFQ95789.1 - 5e-13 49.0 0.1 2.7e-12 46.7 0.0 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch PQQ_3 PF13570.6 KFQ95789.1 - 0.26 11.8 7.5 1.8 9.1 0.1 4.5 5 0 0 5 5 5 0 PQQ-like domain XPA_C PF05181.12 KFQ95789.1 - 0.34 10.9 4.1 38 4.3 0.0 4.3 6 0 0 6 6 6 0 XPA protein C-terminus PIN_4 PF13638.6 KFQ95790.1 - 2.3e-31 108.8 0.4 2.3e-30 105.6 0.1 2.3 2 1 0 2 2 2 1 PIN domain PIN_12 PF16289.5 KFQ95790.1 - 0.0012 19.3 0.9 0.0032 18.0 0.0 2.1 2 1 0 2 2 2 1 PIN domain PIN_9 PF18477.1 KFQ95790.1 - 0.0037 17.6 0.1 0.021 15.1 0.1 2.4 1 1 0 1 1 1 1 PIN like domain Plasmid_RAQPRD PF09686.10 KFQ95790.1 - 0.052 13.8 0.0 15 5.9 0.0 2.6 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Mitofilin PF09731.9 KFQ95790.1 - 0.074 11.9 0.1 0.49 9.2 0.1 1.9 1 1 1 2 2 2 0 Mitochondrial inner membrane protein DUF953 PF06110.11 KFQ95791.1 - 0.02 14.5 0.0 1.1 8.9 0.0 2.3 1 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) WDCP PF15390.6 KFQ95791.1 - 0.19 10.1 2.5 0.24 9.7 2.5 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family TRM PF02005.16 KFQ95792.1 - 9.2e-69 232.4 5.6 1.3e-57 195.7 1.1 3.3 2 1 1 3 3 3 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 KFQ95792.1 - 0.00024 20.9 0.1 0.00054 19.8 0.1 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 KFQ95792.1 - 0.0037 17.9 0.3 1 10.1 0.1 3.4 2 1 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KFQ95792.1 - 0.051 13.2 0.1 0.27 10.8 0.1 2.0 1 1 0 1 1 1 0 Conserved hypothetical protein 95 MTS PF05175.14 KFQ95792.1 - 0.053 13.1 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 KFQ95792.1 - 0.065 13.0 0.1 0.18 11.6 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain RAWUL PF16207.5 KFQ95793.1 - 6.3e-30 103.7 0.2 1.4e-29 102.6 0.2 1.6 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 KFQ95793.1 - 4.8e-16 58.3 10.3 8.1e-16 57.6 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ95793.1 - 5.6e-10 38.9 10.4 1e-09 38.1 10.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ95793.1 - 5.4e-09 36.2 8.5 9.2e-09 35.5 8.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFQ95793.1 - 6.2e-08 32.4 7.9 9.3e-08 31.8 7.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFQ95793.1 - 5.6e-06 26.3 8.0 1.1e-05 25.3 8.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFQ95793.1 - 1.6e-05 24.7 8.5 3e-05 23.9 8.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFQ95793.1 - 4.9e-05 23.4 7.6 9.6e-05 22.5 7.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KFQ95793.1 - 0.00021 21.1 5.5 0.00036 20.3 5.5 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KFQ95793.1 - 0.00023 20.9 6.6 0.00048 19.8 6.6 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KFQ95793.1 - 0.001 18.9 3.7 0.0018 18.1 3.7 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KFQ95793.1 - 0.0015 18.7 7.1 0.0046 17.2 7.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_5 PF17121.5 KFQ95793.1 - 0.035 14.0 7.1 0.34 10.8 7.4 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 KFQ95793.1 - 0.042 13.9 1.9 0.14 12.3 1.9 1.9 1 0 0 1 1 1 0 Zinc-binding RING-finger Prok-RING_4 PF14447.6 KFQ95793.1 - 0.066 13.1 8.4 0.9 9.4 8.8 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFQ95793.1 - 0.21 11.6 2.5 0.43 10.7 2.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KFQ95793.1 - 0.39 10.5 4.6 0.95 9.3 4.6 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-MIZ PF02891.20 KFQ95793.1 - 0.76 9.6 6.8 1.5 8.7 6.8 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C4_Topoisom PF01396.19 KFQ95793.1 - 2.1 8.2 5.1 0.27 11.1 0.9 1.7 2 0 0 2 2 1 0 Topoisomerase DNA binding C4 zinc finger Glyco_hydro_47 PF01532.20 KFQ95795.1 - 9.3e-107 357.7 0.0 1.8e-106 356.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 KFQ95795.1 - 1.4e-12 47.5 0.1 3.1e-12 46.4 0.1 1.6 1 0 0 1 1 1 1 PA domain DUF4612 PF15389.6 KFQ95796.1 - 8.3e-38 130.0 4.7 9e-38 129.8 4.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4612) Sen15 PF09631.10 KFQ95797.1 - 3.1e-27 94.8 0.0 4e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein PCNA_C PF02747.15 KFQ95797.1 - 0.1 12.8 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, C-terminal domain RasGEF PF00617.19 KFQ95798.1 - 1.5e-59 201.2 1.7 1.5e-59 201.2 1.7 1.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KFQ95798.1 - 1.4e-19 70.2 0.0 7.1e-19 68.0 0.0 2.2 1 0 0 1 1 1 1 RasGEF N-terminal motif RA PF00788.23 KFQ95798.1 - 2.4e-15 56.9 0.2 1.3e-13 51.4 0.0 2.9 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain DUF5423 PF17461.2 KFQ95798.1 - 0.02 13.8 12.3 0.033 13.1 12.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Acyl-CoA_ox_N PF14749.6 KFQ95798.1 - 0.056 14.0 3.6 10 6.7 0.1 3.4 3 1 0 3 3 3 0 Acyl-coenzyme A oxidase N-terminal APOBEC4 PF18775.1 KFQ95799.1 - 2.1e-30 104.7 0.9 2.7e-30 104.3 0.9 1.1 1 0 0 1 1 1 1 APOBEC4 NAD1 PF18778.1 KFQ95799.1 - 1.2e-20 74.4 0.1 1.3e-20 74.2 0.1 1.0 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 KFQ95799.1 - 5.1e-20 72.1 0.0 5.9e-20 71.9 0.0 1.0 1 0 0 1 1 1 1 APOBEC-like N-terminal domain SNAD4 PF18750.1 KFQ95799.1 - 3e-13 49.9 0.1 3.8e-13 49.6 0.1 1.1 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC1 PF18769.1 KFQ95799.1 - 2.2e-06 27.9 0.0 3.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 APOBEC1 APOBEC4_like PF18774.1 KFQ95799.1 - 1e-05 25.5 0.0 1.2e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase APOBEC2 PF18772.1 KFQ95799.1 - 1.2e-05 25.5 0.4 1.3e-05 25.3 0.4 1.1 1 0 0 1 1 1 1 APOBEC2 NAD2 PF18782.1 KFQ95799.1 - 1.6e-05 25.1 0.6 1.8e-05 25.0 0.6 1.1 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC3 PF18771.1 KFQ95799.1 - 0.00083 19.5 0.2 0.00098 19.3 0.2 1.1 1 0 0 1 1 1 1 APOBEC3 Toxin-deaminase PF14424.6 KFQ95799.1 - 0.15 12.2 0.3 0.19 11.8 0.3 1.1 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases P16-Arc PF04699.14 KFQ95800.1 - 4.5e-48 163.5 0.1 5e-48 163.4 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 KFQ95800.1 - 0.0045 17.3 0.0 0.0062 16.8 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family SH3_1 PF00018.28 KFQ95801.1 - 5.9e-28 96.2 0.1 1.5e-15 56.5 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KFQ95801.1 - 9e-23 79.9 0.1 2e-12 46.8 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KFQ95801.1 - 4.9e-18 64.6 0.0 1.7e-11 43.6 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain TPR_1 PF00515.28 KFQ95801.1 - 9e-17 60.1 1.0 6.3e-05 22.6 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ95801.1 - 8.6e-16 56.7 1.2 0.0018 18.2 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ95801.1 - 3.4e-09 36.8 1.4 0.003 17.8 0.2 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ95801.1 - 3.4e-09 36.2 0.8 0.0086 16.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat PB1 PF00564.24 KFQ95801.1 - 3.2e-07 30.2 0.0 6.6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 PB1 domain TPR_7 PF13176.6 KFQ95801.1 - 4e-06 26.5 0.3 0.068 13.2 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ95801.1 - 0.00013 22.5 0.0 0.0085 16.7 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFQ95801.1 - 0.0019 18.3 0.1 1.5 9.0 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFQ95801.1 - 0.0022 18.5 1.0 18 6.2 0.1 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ95801.1 - 0.0032 17.3 0.4 6 6.9 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ95801.1 - 0.0045 17.3 0.0 4.1 8.0 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Cobl PF09469.10 KFQ95801.1 - 0.016 15.5 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain Cohesin_load PF10345.9 KFQ95801.1 - 0.023 13.2 0.7 0.034 12.6 0.7 1.1 1 0 0 1 1 1 0 Cohesin loading factor TPR_11 PF13414.6 KFQ95801.1 - 0.046 13.4 1.0 0.94 9.2 0.1 3.0 2 1 1 3 3 3 0 TPR repeat EST1_DNA_bind PF10373.9 KFQ95802.1 - 1e-55 189.2 4.7 1e-55 189.2 4.7 2.2 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KFQ95802.1 - 4.5e-25 88.9 0.3 4.5e-25 88.9 0.3 2.6 2 0 0 2 2 2 1 Telomerase activating protein Est1 zf-AD PF07776.15 KFQ95802.1 - 0.0047 17.1 0.6 0.02 15.1 0.6 2.1 1 1 0 1 1 1 1 Zinc-finger associated domain (zf-AD) TPR_2 PF07719.17 KFQ95802.1 - 0.053 13.7 0.0 0.19 12.0 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ95802.1 - 0.062 13.4 0.6 0.26 11.4 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ95802.1 - 0.22 12.0 1.1 0.67 10.5 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Ferlin_C PF16165.5 KFQ95802.1 - 0.55 10.2 2.1 1.3 9.0 2.1 1.6 1 0 0 1 1 1 0 Ferlin C-terminus CTP_transf_like PF01467.26 KFQ95803.1 - 5.8e-16 59.0 0.0 1.1e-14 54.8 0.0 2.1 1 1 0 1 1 1 1 Cytidylyltransferase-like Laminin_EGF PF00053.24 KFQ95804.1 - 8.5e-41 137.9 143.7 1.7e-09 37.7 11.5 8.6 8 0 0 8 8 8 7 Laminin EGF domain Laminin_B PF00052.18 KFQ95804.1 - 5.9e-28 97.4 0.1 3.6e-27 94.9 0.0 2.3 3 0 0 3 3 3 1 Laminin B (Domain IV) Spc7 PF08317.11 KFQ95804.1 - 0.00094 18.2 13.2 0.00094 18.2 13.2 4.3 2 1 2 4 4 4 3 Spc7 kinetochore protein Sec34 PF04136.15 KFQ95804.1 - 0.95 9.3 11.4 4.6 7.1 0.4 4.6 5 0 0 5 5 5 0 Sec34-like family Fib_alpha PF08702.10 KFQ95804.1 - 2 8.6 16.7 11 6.1 2.0 4.7 3 1 0 4 4 4 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.12 KFQ95805.1 - 0.0002 21.4 19.6 0.0086 16.1 4.4 3.1 1 1 2 3 3 3 2 Laminin Domain II WXG100 PF06013.12 KFQ95805.1 - 0.0049 17.1 7.6 0.0049 17.1 7.6 3.8 1 1 3 4 4 4 1 Proteins of 100 residues with WXG BST2 PF16716.5 KFQ95805.1 - 0.014 16.0 3.1 0.014 16.0 3.1 3.0 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 PRESAN PF09687.10 KFQ95805.1 - 0.017 15.7 0.9 0.48 11.0 0.6 2.2 2 1 0 2 2 2 0 Plasmodium RESA N-terminal CODH_A_N PF18537.1 KFQ95805.1 - 0.02 14.9 3.4 0.81 9.8 0.4 2.9 2 1 0 2 2 2 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain AAA_13 PF13166.6 KFQ95805.1 - 0.025 13.2 19.7 0.033 12.9 19.7 1.0 1 0 0 1 1 1 0 AAA domain DUF948 PF06103.11 KFQ95805.1 - 0.083 13.1 13.8 0.24 11.7 1.8 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Herpes_UL6 PF01763.16 KFQ95805.1 - 0.086 11.3 13.1 0.76 8.2 4.5 2.1 1 1 1 2 2 2 0 Herpesvirus UL6 like Orthopox_B11R PF07033.11 KFQ95805.1 - 0.13 12.1 1.1 0.26 11.1 0.1 2.0 2 0 0 2 2 2 0 Orthopoxvirus B11R protein Med30 PF11315.8 KFQ95805.1 - 0.2 11.8 9.8 0.23 11.7 9.2 1.3 1 1 0 1 1 1 0 Mediator complex subunit 30 DHR10 PF18595.1 KFQ95805.1 - 0.23 11.5 25.5 1.5 8.9 7.8 2.9 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain DUF2203 PF09969.9 KFQ95805.1 - 0.29 11.9 14.6 0.19 12.4 4.6 2.6 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) SKA1 PF07160.12 KFQ95805.1 - 0.32 10.8 9.0 3.5 7.4 2.4 2.6 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 BLOC1_2 PF10046.9 KFQ95805.1 - 0.36 11.2 20.3 2.1 8.7 1.8 4.0 1 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Bep_C_terminal PF17841.1 KFQ95805.1 - 0.37 11.1 7.8 0.19 12.0 5.7 1.7 2 0 0 2 2 1 0 BID domain of Bartonella effector protein (Bep) DUF3450 PF11932.8 KFQ95805.1 - 0.39 10.0 24.5 2.9 7.1 2.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Med9 PF07544.13 KFQ95805.1 - 0.51 10.5 11.0 1.1 9.4 0.5 3.3 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 FUSC PF04632.12 KFQ95805.1 - 0.57 8.6 8.0 0.36 9.3 6.7 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family TPR_MLP1_2 PF07926.12 KFQ95805.1 - 0.63 10.1 25.9 0.11 12.6 13.9 3.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein SesA PF17107.5 KFQ95805.1 - 0.72 10.1 12.2 4.9 7.4 0.5 3.5 1 1 2 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases HisKA PF00512.25 KFQ95805.1 - 0.79 9.8 5.2 0.91 9.6 1.0 2.8 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain LMBR1 PF04791.16 KFQ95805.1 - 1 8.2 6.4 1.3 7.9 6.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Prominin PF05478.11 KFQ95805.1 - 1.2 7.0 10.0 2.9 5.7 10.0 1.5 1 1 0 1 1 1 0 Prominin APG6_N PF17675.1 KFQ95805.1 - 1.2 9.6 24.7 0.25 11.9 11.1 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 KFQ95805.1 - 1.4 9.2 24.1 1.8 8.8 3.4 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.11 KFQ95805.1 - 1.6 9.2 11.3 18 5.8 0.5 4.2 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 KFQ95805.1 - 1.9 8.5 15.4 4.3 7.4 2.5 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) TRAF_BIRC3_bd PF16673.5 KFQ95805.1 - 2.1 8.2 7.7 8.9 6.2 0.1 3.3 4 0 0 4 4 3 0 TNF receptor-associated factor BIRC3 binding domain HsbA PF12296.8 KFQ95805.1 - 2.3 8.7 13.8 5.8 7.4 10.0 2.8 1 1 0 2 2 2 0 Hydrophobic surface binding protein A Syntaxin PF00804.25 KFQ95805.1 - 2.9 7.5 15.6 1 9.0 6.2 2.4 1 1 1 2 2 2 0 Syntaxin End3 PF12761.7 KFQ95805.1 - 3.4 7.8 18.8 3.3 7.8 14.0 2.1 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DUF2201_N PF13203.6 KFQ95805.1 - 4.1 6.9 10.0 2 7.9 7.4 1.7 2 0 0 2 2 2 0 Putative metallopeptidase domain DUF745 PF05335.13 KFQ95805.1 - 4.4 7.0 28.8 8.2 6.1 28.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF745) GET2 PF08690.10 KFQ95805.1 - 4.7 6.8 19.4 0.75 9.4 11.4 2.0 1 1 0 2 2 2 0 GET complex subunit GET2 OmpH PF03938.14 KFQ95805.1 - 5.3 7.4 25.5 0.66 10.3 14.1 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) PepSY_TM_like_2 PF16357.5 KFQ95805.1 - 6 6.8 8.5 2.1 8.3 3.4 1.9 2 0 0 2 2 2 0 Putative PepSY_TM-like TMPIT PF07851.13 KFQ95805.1 - 6.6 5.9 14.6 3.1 6.9 6.4 2.1 1 1 1 2 2 2 0 TMPIT-like protein Alanine_zipper PF11839.8 KFQ95805.1 - 7.3 7.0 41.9 3.3 8.2 17.1 3.2 2 2 2 4 4 4 0 Alanine-zipper, major outer membrane lipoprotein ArlS_N PF18719.1 KFQ95805.1 - 7.5 6.8 8.0 1.2 9.3 2.7 2.2 1 1 0 2 2 2 0 ArlS sensor domain HisKA_3 PF07730.13 KFQ95805.1 - 7.5 7.2 18.1 2.4 8.7 2.0 4.2 1 1 4 5 5 5 0 Histidine kinase SlyX PF04102.12 KFQ95805.1 - 9.7 6.9 13.1 3.4 8.3 0.5 3.2 1 1 2 3 3 3 0 SlyX OB_NTP_bind PF07717.16 KFQ95806.1 - 4.5e-14 52.6 0.0 8e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold dsrm PF00035.26 KFQ95807.1 - 2.9e-18 66.3 0.3 1.9e-11 44.5 0.2 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif Helicase_C PF00271.31 KFQ95807.1 - 1.3e-15 57.7 0.0 3.3e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFQ95807.1 - 2.2e-07 30.8 0.0 8.5e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase HA2 PF04408.23 KFQ95807.1 - 2.5e-05 24.5 0.3 7.2e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) AAA_14 PF13173.6 KFQ95807.1 - 0.012 15.7 0.1 0.068 13.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Dicer_dimer PF03368.14 KFQ95807.1 - 0.016 15.3 0.1 0.13 12.5 0.0 2.5 3 0 0 3 3 3 0 Dicer dimerisation domain T2SSE PF00437.20 KFQ95807.1 - 0.02 14.0 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 KFQ95807.1 - 0.027 14.5 0.4 0.5 10.3 0.0 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit ATPase PF06745.13 KFQ95807.1 - 0.034 13.5 0.0 0.086 12.2 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 KFQ95807.1 - 0.037 14.4 0.0 0.1 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFQ95807.1 - 0.076 13.3 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KFQ95807.1 - 0.083 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Ploopntkinase2 PF18747.1 KFQ95807.1 - 0.12 11.6 0.0 0.28 10.4 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase2 DHDPS PF00701.22 KFQ95808.1 - 2.8e-47 160.8 0.0 3.2e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family SOUL PF04832.12 KFQ95809.1 - 3.2e-48 164.1 0.1 3.9e-48 163.8 0.1 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein BTB PF00651.31 KFQ95810.1 - 6.4e-27 94.0 0.3 1.1e-26 93.3 0.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFQ95810.1 - 4.3e-16 58.5 18.0 4.2e-07 30.1 4.1 4.4 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ95810.1 - 3.2e-12 46.2 20.7 2.1e-05 24.7 1.9 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ95810.1 - 2.4e-09 37.2 18.3 0.0042 17.8 1.1 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger DUF3342 PF11822.8 KFQ95810.1 - 1.8e-05 24.8 0.1 3.5e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) zf-C2H2_2 PF12756.7 KFQ95810.1 - 0.00073 19.8 7.5 0.076 13.4 0.0 3.5 1 1 2 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFQ95810.1 - 0.0017 18.7 16.6 0.035 14.5 0.7 4.4 5 0 0 5 5 3 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFQ95810.1 - 0.0028 17.4 3.7 1.2 8.9 0.2 2.9 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFQ95810.1 - 0.011 16.1 9.9 0.11 12.9 0.1 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KFQ95810.1 - 0.079 13.4 8.9 2.3 8.7 1.2 3.5 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger BTB_2 PF02214.22 KFQ95810.1 - 0.11 12.8 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain PyrI_C PF02748.15 KFQ95810.1 - 0.26 11.2 3.4 10 6.1 0.1 3.2 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zinc_ribbon_15 PF17032.5 KFQ95810.1 - 0.3 11.9 2.8 1.1 10.1 0.7 2.3 1 1 1 2 2 2 0 zinc-ribbon family zf-Di19 PF05605.12 KFQ95810.1 - 0.53 10.6 9.0 0.12 12.6 0.8 2.5 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Elf1 PF05129.13 KFQ95810.1 - 0.91 9.6 3.3 0.85 9.7 0.6 2.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-AN1 PF01428.16 KFQ95810.1 - 1.3 9.2 7.0 19 5.5 0.1 3.3 3 0 0 3 3 3 0 AN1-like Zinc finger zf_C2H2_ZHX PF18387.1 KFQ95810.1 - 1.6 8.5 9.0 16 5.2 0.2 3.3 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain HNH_5 PF14279.6 KFQ95810.1 - 1.9 8.4 5.2 27 4.7 0.1 3.3 3 0 0 3 3 3 0 HNH endonuclease zf-trcl PF13451.6 KFQ95810.1 - 2.2 8.2 5.6 2.4 8.1 0.2 2.6 2 1 1 3 3 3 0 Probable zinc-ribbon domain zf-C2H2_11 PF16622.5 KFQ95810.1 - 2.8 7.8 15.7 2.4 8.0 1.0 3.7 4 0 0 4 4 3 0 zinc-finger C2H2-type zf-BED PF02892.15 KFQ95810.1 - 3.4 7.8 16.2 4.7 7.3 0.6 3.5 1 1 1 2 2 2 0 BED zinc finger PriA_CRR PF18319.1 KFQ95810.1 - 4.2 7.4 7.8 27 4.9 0.9 3.3 3 0 0 3 3 3 0 PriA DNA helicase Cys-rich region (CRR) domain zf-C2H2_6 PF13912.6 KFQ95810.1 - 4.6 7.4 13.7 0.75 9.9 1.6 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KFQ95810.1 - 6.2 7.5 8.1 19 5.9 0.7 3.3 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats ROQ_II PF18386.1 KFQ95811.1 - 2.1e-33 113.9 0.6 4e-33 113.0 0.6 1.5 1 0 0 1 1 1 1 Roquin II domain zf-RING_UBOX PF13445.6 KFQ95811.1 - 3.8e-06 26.8 6.7 9.5e-06 25.5 6.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFQ95811.1 - 5.1e-06 26.2 6.3 0.00011 22.0 1.6 2.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFQ95811.1 - 1.6e-05 24.6 3.8 3.2e-05 23.7 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ95811.1 - 2.6e-05 24.5 6.4 5.4e-05 23.4 6.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KFQ95811.1 - 3.4e-05 23.9 5.1 7.5e-05 22.8 5.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KFQ95811.1 - 4e-05 23.5 6.4 8e-05 22.5 6.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFQ95811.1 - 0.00017 21.4 7.2 0.00034 20.4 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.24 KFQ95811.1 - 0.00026 20.8 3.0 0.00026 20.8 3.0 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.6 KFQ95811.1 - 0.0015 18.3 7.4 0.0037 17.1 7.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KFQ95811.1 - 0.0019 18.3 1.3 0.0039 17.3 1.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf_CCCH_4 PF18345.1 KFQ95811.1 - 0.0077 16.3 2.4 0.023 14.8 2.4 1.9 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KFQ95811.1 - 0.033 14.0 2.0 0.07 13.0 2.0 1.6 1 0 0 1 1 1 0 CCCH-type zinc finger PaaA_PaaC PF05138.12 KFQ95811.1 - 0.038 13.1 0.1 0.066 12.4 0.1 1.3 1 0 0 1 1 1 0 Phenylacetic acid catabolic protein DUF743 PF05332.11 KFQ95811.1 - 0.04 14.0 0.1 0.18 11.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF743) Baculo_IE-1 PF05290.11 KFQ95811.1 - 0.057 13.4 1.5 0.13 12.2 1.5 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 KFQ95811.1 - 0.063 13.1 4.9 0.14 12.0 4.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 KFQ95811.1 - 0.22 11.7 8.0 0.089 12.9 4.1 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KFQ95811.1 - 0.24 11.3 1.3 0.5 10.3 1.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_5 PF17121.5 KFQ95811.1 - 0.58 10.1 2.8 1.6 8.7 2.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CS PF04969.16 KFQ95812.1 - 2.7e-15 57.1 1.3 6.7e-15 55.9 0.2 2.0 2 0 0 2 2 2 1 CS domain Siah-Interact_N PF09032.11 KFQ95812.1 - 9.9e-15 54.6 2.9 9.9e-15 54.6 2.9 2.3 2 0 0 2 2 2 1 Siah interacting protein, N terminal SGS PF05002.15 KFQ95812.1 - 2.6e-06 27.4 2.4 6e-06 26.3 2.4 1.6 1 0 0 1 1 1 1 SGS domain DUF3290 PF11694.8 KFQ95812.1 - 0.1 12.6 0.2 0.19 11.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Pih1_fungal_CS PF18482.1 KFQ95812.1 - 0.16 12.5 3.6 0.32 11.6 0.5 2.6 2 1 1 3 3 3 0 Fungal Pih1 CS domain Ribosomal_S14 PF00253.21 KFQ95813.1 - 3.4e-23 81.2 3.0 3.8e-21 74.6 0.8 2.2 2 0 0 2 2 2 2 Ribosomal protein S14p/S29e Fibrinogen_C PF00147.18 KFQ95814.1 - 1.8e-80 269.9 6.4 3.1e-80 269.1 6.4 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain fn3 PF00041.21 KFQ95814.1 - 1.1e-76 253.2 15.9 1.3e-15 57.5 0.1 6.5 6 0 0 6 6 6 6 Fibronectin type III domain DUF4998 PF16389.5 KFQ95814.1 - 1.9e-14 53.7 0.8 0.01 15.4 0.1 4.5 4 0 0 4 4 4 4 Domain of unknown function EGF_2 PF07974.13 KFQ95814.1 - 3.3e-12 46.5 74.4 0.00039 20.7 9.3 4.9 4 1 0 4 4 4 3 EGF-like domain Interfer-bind PF09294.10 KFQ95814.1 - 1.2e-08 35.2 0.2 1.8 8.9 0.0 5.7 6 0 0 6 6 6 2 Interferon-alpha/beta receptor, fibronectin type III Pur_ac_phosph_N PF16656.5 KFQ95814.1 - 7.6e-07 29.6 20.3 2 9.1 2.3 8.1 4 3 1 5 5 5 4 Purple acid Phosphatase, N-terminal domain CBM_4_9 PF02018.17 KFQ95814.1 - 3.8e-05 24.0 7.5 1.1 9.5 0.0 5.5 3 2 0 6 6 6 2 Carbohydrate binding domain EGF_Tenascin PF18720.1 KFQ95814.1 - 0.00068 19.6 12.1 0.00068 19.6 12.1 4.5 4 0 0 4 4 4 3 Tenascin EGF domain DUF1541 PF07563.11 KFQ95814.1 - 0.047 13.6 0.5 36 4.4 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1541) TSC22 PF01166.18 KFQ95814.1 - 0.14 12.4 0.1 0.33 11.3 0.1 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family fn3 PF00041.21 KFQ95815.1 - 4.4e-120 392.3 21.4 6.9e-16 58.4 0.1 9.3 9 0 0 9 9 9 9 Fibronectin type III domain Fibrinogen_C PF00147.18 KFQ95815.1 - 7.8e-81 271.1 8.0 1.5e-80 270.2 8.0 1.5 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain EGF_Tenascin PF18720.1 KFQ95815.1 - 2.8e-29 100.6 87.4 1.5e-11 44.1 14.8 5.3 5 0 0 5 5 4 4 Tenascin EGF domain Pur_ac_phosph_N PF16656.5 KFQ95815.1 - 1.9e-13 50.8 23.6 0.55 10.8 0.0 11.2 7 7 0 7 7 7 5 Purple acid Phosphatase, N-terminal domain EGF_2 PF07974.13 KFQ95815.1 - 5.8e-12 45.8 88.1 0.0024 18.2 10.9 5.8 5 0 0 5 5 5 5 EGF-like domain Interfer-bind PF09294.10 KFQ95815.1 - 5.3e-11 42.8 0.0 1.3 9.3 0.0 8.0 9 0 0 9 9 9 2 Interferon-alpha/beta receptor, fibronectin type III fn3_2 PF16893.5 KFQ95815.1 - 3.3e-06 27.2 1.9 26 5.0 0.0 7.2 8 1 0 8 8 8 0 Fibronectin type III domain DUF2369 PF10179.9 KFQ95815.1 - 1.3e-05 25.5 2.6 48 4.4 0.0 6.8 7 2 1 8 8 8 0 Uncharacterised conserved protein (DUF2369) CBM_4_9 PF02018.17 KFQ95815.1 - 1.9e-05 24.9 4.4 10 6.4 0.0 6.9 5 2 3 9 9 8 1 Carbohydrate binding domain DUF4998 PF16389.5 KFQ95815.1 - 0.00031 20.4 0.0 2.8 7.5 0.0 4.5 5 0 0 5 5 5 1 Domain of unknown function Big_10 PF17964.1 KFQ95815.1 - 0.001 19.1 8.8 9.3 6.2 0.1 6.1 6 1 1 7 7 7 2 Bacterial Ig domain DUF4959 PF16323.5 KFQ95815.1 - 0.0013 19.1 0.1 1.1 9.6 0.0 3.6 2 1 2 4 4 4 1 Domain of unknown function (DUF4959) Lzipper-MIP1 PF14389.6 KFQ95815.1 - 0.011 16.0 0.1 0.026 14.8 0.1 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Uroplakin_II PF07353.12 KFQ95815.1 - 0.076 12.5 1.0 5.4 6.5 0.1 3.7 5 0 0 5 5 5 0 Uroplakin II DUF1192 PF06698.11 KFQ95815.1 - 0.22 11.6 0.0 0.53 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) WD40 PF00400.32 KFQ95816.1 - 1.3e-22 79.6 4.4 0.032 15.1 0.0 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat zf-C3HC4_2 PF13923.6 KFQ95816.1 - 7.2e-15 54.6 7.8 1.8e-14 53.3 7.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ95816.1 - 2.2e-09 37.0 8.6 6.5e-09 35.5 8.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFQ95816.1 - 2.5e-07 30.6 4.1 9e-07 28.8 4.1 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFQ95816.1 - 2.6e-07 30.5 7.4 2.6e-07 30.5 7.4 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFQ95816.1 - 5.3e-07 29.4 5.5 1.4e-06 28.1 5.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ95816.1 - 5.4e-07 29.8 7.1 5.4e-07 29.8 7.1 2.8 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KFQ95816.1 - 7.1e-06 26.1 7.5 2.6e-05 24.3 7.5 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KFQ95816.1 - 9.2e-05 22.7 3.7 9.2e-05 22.7 3.7 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain ANAPC4_WD40 PF12894.7 KFQ95816.1 - 0.00014 22.1 0.4 1.6 9.1 0.0 4.3 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFQ95816.1 - 0.0003 20.2 0.0 0.0018 17.7 0.0 2.1 1 1 1 2 2 2 1 WD40-like domain zf-RING_4 PF14570.6 KFQ95816.1 - 0.0057 16.4 7.1 0.015 15.1 7.1 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KFQ95816.1 - 0.0064 16.3 5.2 0.017 15.0 5.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf_C2H2_10 PF18414.1 KFQ95816.1 - 0.041 13.4 0.1 0.13 11.8 0.1 1.9 1 0 0 1 1 1 0 C2H2 type zinc-finger zf-RING_10 PF16685.5 KFQ95816.1 - 0.05 13.7 2.2 0.17 12.1 2.2 1.9 1 0 0 1 1 1 0 zinc RING finger of MSL2 AAA_23 PF13476.6 KFQ95816.1 - 7.4 7.0 6.8 16 6.0 6.8 1.5 1 0 0 1 1 1 0 AAA domain Laminin_G_3 PF13385.6 KFQ95817.1 - 2.3e-14 53.8 0.1 7.5e-14 52.1 0.1 1.8 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Peptidase_M43 PF05572.13 KFQ95817.1 - 1.5e-11 44.4 0.3 1.5e-11 44.4 0.3 2.3 3 0 0 3 3 3 1 Pregnancy-associated plasma protein-A Sushi PF00084.20 KFQ95817.1 - 2.5e-06 28.0 1.9 2.5e-06 28.0 1.9 8.5 9 0 0 9 9 9 3 Sushi repeat (SCR repeat) Notch PF00066.17 KFQ95817.1 - 3.4e-05 24.2 1.3 3.4e-05 24.2 1.3 6.7 7 1 0 7 7 7 3 LNR domain DUF4215 PF13948.6 KFQ95817.1 - 8.1e-05 23.0 2.5 8.1e-05 23.0 2.5 5.7 6 0 0 6 6 6 1 Domain of unknown function (DUF4215) Reprolysin_3 PF13582.6 KFQ95817.1 - 0.015 15.8 0.2 0.015 15.8 0.2 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 KFQ95817.1 - 0.092 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M66 PF10462.9 KFQ95817.1 - 0.22 10.4 1.8 0.43 9.5 1.8 1.4 1 0 0 1 1 1 0 Peptidase M66 Annexin_like PF18411.1 KFQ95818.1 - 1.2e-49 166.5 0.0 2.6e-49 165.4 0.0 1.6 1 0 0 1 1 1 1 Annexin-like domain FXa_inhibition PF14670.6 KFQ95818.1 - 3.1e-10 40.1 33.9 3.8e-09 36.7 3.7 4.1 3 0 0 3 3 3 2 Coagulation Factor Xa inhibitory site ASTN_2_hairpin PF18577.1 KFQ95818.1 - 0.00076 19.5 0.1 0.0018 18.3 0.1 1.6 1 0 0 1 1 1 1 Astrotactin-2 C-terminal beta-hairpin domain MACPF PF01823.19 KFQ95818.1 - 0.001 19.2 0.1 0.0022 18.2 0.1 1.4 1 0 0 1 1 1 1 MAC/Perforin domain UPF0560 PF10577.9 KFQ95818.1 - 0.08 11.4 0.4 0.15 10.5 0.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 fn3 PF00041.21 KFQ95818.1 - 0.09 13.1 0.0 0.71 10.3 0.0 2.2 1 1 0 1 1 1 0 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFQ95818.1 - 0.11 13.1 0.0 0.46 11.1 0.0 2.0 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 KFQ95818.1 - 0.13 12.6 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) MACPF PF01823.19 KFQ95819.1 - 5.5e-06 26.6 0.0 1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 MAC/Perforin domain OGG_N PF07934.12 KFQ95819.1 - 0.0049 16.9 3.8 8.9 6.4 0.2 4.0 3 1 1 4 4 4 2 8-oxoguanine DNA glycosylase, N-terminal domain Sec16_C PF12931.7 KFQ95820.1 - 6.6e-44 150.8 0.0 1.8e-43 149.3 0.0 1.6 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KFQ95820.1 - 1e-07 32.5 0.0 2.5e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region DUF3498 PF12004.8 KFQ95821.1 - 7.8e-199 662.2 45.3 7.8e-199 662.2 45.3 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3498) RasGAP PF00616.19 KFQ95821.1 - 3.5e-26 92.2 13.3 1.2e-16 61.1 0.5 3.9 3 1 1 4 4 4 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KFQ95821.1 - 1.5e-09 38.1 0.1 2.9e-09 37.1 0.1 1.5 1 0 0 1 1 1 1 C2 domain PH PF00169.29 KFQ95821.1 - 0.0001 22.8 0.7 0.36 11.4 0.0 3.8 4 0 0 4 4 3 2 PH domain KASH_CCD PF14662.6 KFQ95821.1 - 0.046 13.6 24.8 0.042 13.7 22.4 2.0 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Bacillus_HBL PF05791.11 KFQ95821.1 - 0.084 12.7 5.6 0.23 11.3 5.6 1.7 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) PH_6 PF15406.6 KFQ95821.1 - 0.11 12.9 0.0 0.36 11.1 0.0 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain LptF_LptG PF03739.14 KFQ95821.1 - 0.24 10.2 3.6 0.42 9.4 3.6 1.3 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG XLF PF09302.11 KFQ95821.1 - 0.35 11.0 10.7 0.35 11.0 8.8 1.9 2 0 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Exonuc_VII_L PF02601.15 KFQ95821.1 - 0.57 9.7 12.4 1.2 8.6 12.4 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit FliD_C PF07195.12 KFQ95821.1 - 1 8.8 11.9 4 6.8 2.8 2.7 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus PIN_8 PF18476.1 KFQ95821.1 - 1.4 8.8 11.0 3.1 7.6 11.0 1.5 1 0 0 1 1 1 0 PIN like domain Prominin PF05478.11 KFQ95821.1 - 2.1 6.2 8.7 3.6 5.4 8.7 1.3 1 0 0 1 1 1 0 Prominin V_ATPase_I PF01496.19 KFQ95821.1 - 8.9 4.1 11.0 16 3.2 11.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RasGEF PF00617.19 KFQ95822.1 - 4.5e-53 180.1 0.2 1.5e-52 178.4 0.1 1.8 1 1 1 2 2 2 1 RasGEF domain PH PF00169.29 KFQ95822.1 - 1.3e-09 38.5 0.1 3e-09 37.3 0.1 1.7 1 0 0 1 1 1 1 PH domain CRISPR_Cas9_WED PF18061.1 KFQ95822.1 - 0.012 15.7 0.1 0.023 14.8 0.1 1.4 1 0 0 1 1 1 0 CRISPR-Cas9 WED domain Fibrinogen_C PF00147.18 KFQ95823.1 - 4.4e-73 245.7 10.3 5.9e-73 245.3 10.3 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain ZirS_C PF16583.5 KFQ95823.1 - 0.02 14.5 0.2 0.22 11.1 0.1 2.2 2 0 0 2 2 2 0 Zinc-regulated secreted antivirulence protein C-terminal domain SlyX PF04102.12 KFQ95823.1 - 1.5 9.5 5.5 6.5 7.5 0.6 2.9 1 1 1 3 3 3 0 SlyX Fam20C PF06702.12 KFQ95824.1 - 8.4e-87 290.6 0.0 1.2e-86 290.0 0.0 1.2 1 0 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 FAM198 PF15051.6 KFQ95824.1 - 0.0019 17.1 0.0 0.0034 16.3 0.0 1.4 1 0 0 1 1 1 1 FAM198 protein Torsin PF06309.11 KFQ95825.1 - 3.6e-47 159.6 0.7 5.9e-47 158.9 0.7 1.4 1 0 0 1 1 1 1 Torsin AAA_22 PF13401.6 KFQ95825.1 - 0.00036 20.8 0.1 0.025 14.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KFQ95825.1 - 0.00043 20.7 0.0 0.00059 20.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFQ95825.1 - 0.0091 16.4 0.0 0.053 13.9 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain PIF1 PF05970.14 KFQ95825.1 - 0.0094 15.2 0.1 0.034 13.3 0.1 1.7 1 1 0 1 1 1 1 PIF1-like helicase AAA_2 PF07724.14 KFQ95825.1 - 0.019 15.1 0.0 0.083 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 KFQ95825.1 - 0.086 13.2 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA helicase TniB PF05621.11 KFQ95825.1 - 0.12 11.8 0.0 2.6 7.4 0.0 2.1 1 1 0 1 1 1 0 Bacterial TniB protein IstB_IS21 PF01695.17 KFQ95825.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.22 KFQ95825.1 - 0.16 11.1 0.0 0.32 10.2 0.0 1.6 1 1 0 1 1 1 0 NB-ARC domain Pkinase_Tyr PF07714.17 KFQ95826.1 - 2.5e-97 325.2 0.0 3.9e-97 324.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ95826.1 - 7.6e-47 159.9 0.0 1.4e-46 159.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain F_actin_bind PF08919.10 KFQ95826.1 - 5.9e-28 97.2 0.1 1.3e-27 96.1 0.1 1.6 1 0 0 1 1 1 1 F-actin binding SH2 PF00017.24 KFQ95826.1 - 2.2e-24 85.4 0.2 5.1e-24 84.2 0.2 1.7 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFQ95826.1 - 3.6e-12 45.7 0.0 6.7e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFQ95826.1 - 4.7e-07 29.6 0.0 1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFQ95826.1 - 5.2e-07 29.2 0.0 1.1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFQ95826.1 - 3e-05 24.2 0.6 9.2e-05 22.6 0.6 1.9 1 0 0 1 1 1 1 Bacterial SH3 domain Haspin_kinase PF12330.8 KFQ95826.1 - 0.0035 16.3 0.0 0.0071 15.3 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain RGS12_us1 PF16613.5 KFQ95826.1 - 0.03 14.6 2.7 0.11 12.8 2.7 2.0 1 0 0 1 1 1 0 Unstructured region of RGS12 SH3_6 PF12913.7 KFQ95826.1 - 0.057 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 SH3 domain (SH3b1 type) MBOAT PF03062.19 KFQ95827.1 - 2.1e-58 198.3 35.7 3.2e-58 197.7 35.7 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Band_7 PF01145.25 KFQ95828.1 - 2.4e-27 96.1 0.0 2.9e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KFQ95828.1 - 0.0011 18.7 0.2 0.0017 18.1 0.2 1.2 1 0 0 1 1 1 1 SPFH domain-Band 7 family GatB_N PF02934.15 KFQ95828.1 - 0.065 12.6 0.1 0.079 12.3 0.1 1.1 1 0 0 1 1 1 0 GatB/GatE catalytic domain DUF4607 PF15380.6 KFQ95828.1 - 0.068 12.6 0.3 0.11 12.0 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4607) OST-HTH PF12872.7 KFQ95829.1 - 3e-05 23.8 0.0 6.8e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 OST-HTH/LOTUS domain TUDOR PF00567.24 KFQ95830.1 - 3.6e-13 49.6 0.1 8.1e-13 48.5 0.1 1.6 2 0 0 2 2 2 1 Tudor domain FAM163 PF15069.6 KFQ95831.1 - 2.5e-71 239.4 1.1 2.8e-71 239.2 1.1 1.0 1 0 0 1 1 1 1 FAM163 family DUF4006 PF13179.6 KFQ95831.1 - 0.0068 16.3 0.1 0.012 15.6 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF4006) EphA2_TM PF14575.6 KFQ95831.1 - 0.037 14.9 0.0 0.05 14.5 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3169 PF11368.8 KFQ95831.1 - 0.053 13.0 0.0 0.063 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) MscL PF01741.18 KFQ95831.1 - 0.066 13.5 0.0 0.086 13.1 0.0 1.1 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL FAM176 PF14851.6 KFQ95831.1 - 0.086 12.5 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 FAM176 family DUF4576 PF15144.6 KFQ95831.1 - 0.16 11.9 0.1 0.27 11.1 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4576) HCV_NS4a PF01006.20 KFQ95831.1 - 0.43 10.4 3.9 3.5 7.4 3.2 2.5 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a TSP_1 PF00090.19 KFQ95832.1 - 8.9e-27 93.1 116.7 9.3e-07 29.0 12.5 9.4 8 1 0 8 8 8 7 Thrombospondin type 1 domain ADAM_spacer1 PF05986.14 KFQ95832.1 - 2.4e-20 72.7 0.0 4.1e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 PLAC PF08686.11 KFQ95832.1 - 4.7e-10 40.0 10.6 4.7e-10 40.0 10.6 2.9 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain GYR PF02756.14 KFQ95832.1 - 0.26 11.0 1.8 0.59 9.9 1.8 1.6 1 0 0 1 1 1 0 GYR motif LAP1C PF05609.12 KFQ95833.1 - 1.2e-101 341.0 0.1 1.4e-101 340.9 0.1 1.0 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) LAP1C PF05609.12 KFQ95834.1 - 6.7e-104 348.5 0.1 7.4e-104 348.4 0.1 1.0 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) Stap_Strp_tox_C PF02876.17 KFQ95834.1 - 0.025 14.9 0.0 0.062 13.6 0.0 1.6 1 1 0 1 1 1 0 Staphylococcal/Streptococcal toxin, beta-grasp domain QSOX_Trx1 PF18108.1 KFQ95835.1 - 5.8e-45 151.9 0.0 1.8e-44 150.3 0.0 1.9 2 0 0 2 2 2 1 QSOX Trx-like domain FAD_SOX PF18371.1 KFQ95835.1 - 6.6e-43 145.3 0.0 1.6e-42 144.0 0.0 1.7 1 0 0 1 1 1 1 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Evr1_Alr PF04777.13 KFQ95835.1 - 1.1e-25 90.1 0.2 3e-25 88.6 0.2 1.8 2 0 0 2 2 2 1 Erv1 / Alr family Thioredoxin PF00085.20 KFQ95835.1 - 1e-16 60.8 0.0 9.2e-16 57.7 0.1 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 KFQ95835.1 - 0.00015 22.0 0.0 0.1 12.9 0.0 2.9 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KFQ95835.1 - 0.00042 20.7 0.1 1.2 9.6 0.0 3.4 3 0 0 3 3 3 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KFQ95835.1 - 0.0037 16.7 0.0 0.0073 15.7 0.0 1.4 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF3682 PF12446.8 KFQ95835.1 - 0.047 14.2 2.1 0.14 12.7 2.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Thioredoxin_7 PF13899.6 KFQ95835.1 - 0.14 12.4 0.0 3.9 7.7 0.1 2.6 2 0 0 2 2 2 0 Thioredoxin-like Zn-ribbon_8 PF09723.10 KFQ95835.1 - 0.99 9.6 4.7 16 5.7 0.4 2.6 2 0 0 2 2 2 0 Zinc ribbon domain LIM PF00412.22 KFQ95836.1 - 2.4e-32 110.9 19.5 1.1e-16 60.8 2.9 2.2 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 KFQ95836.1 - 1.7e-21 75.8 2.4 2.8e-21 75.1 2.4 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ95836.1 - 0.0001 22.1 0.0 0.00026 20.8 0.0 1.7 1 1 0 1 1 1 1 Homeobox KN domain Furin-like_2 PF15913.5 KFQ95836.1 - 0.0043 17.2 7.1 0.0043 17.2 7.1 2.1 1 1 1 2 2 2 1 Furin-like repeat, cysteine-rich PHF5 PF03660.14 KFQ95836.1 - 1.8 8.8 10.2 0.094 12.9 3.3 2.1 1 1 1 2 2 2 0 PHF5-like protein CDC37_M PF08565.11 KFQ95837.1 - 1.5e-27 95.9 2.3 1.7e-27 95.7 0.5 2.0 1 1 1 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KFQ95837.1 - 5.5e-08 32.9 0.1 5.5e-08 32.9 0.1 4.4 3 2 1 4 4 4 1 Cdc37 C terminal domain T3SSipB PF16535.5 KFQ95837.1 - 0.02 15.4 4.1 0.02 15.4 4.1 1.9 2 1 0 2 2 2 0 Type III cell invasion protein SipB WXG100 PF06013.12 KFQ95837.1 - 0.15 12.3 2.1 13 6.1 0.0 3.1 3 0 0 3 3 3 0 Proteins of 100 residues with WXG DUF4407 PF14362.6 KFQ95837.1 - 0.2 11.0 5.0 0.27 10.6 3.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.11 KFQ95837.1 - 0.23 12.1 11.2 33 5.1 11.2 2.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal LMBR1 PF04791.16 KFQ95837.1 - 0.57 9.0 5.8 0.69 8.8 5.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein KfrA_N PF11740.8 KFQ95837.1 - 0.7 10.6 7.5 5.9 7.6 0.0 3.3 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term DUF1664 PF07889.12 KFQ95837.1 - 4.7 7.3 6.2 5.3 7.1 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PRKG1_interact PF15898.5 KFQ95837.1 - 6.2 7.8 25.6 13 6.8 9.8 3.5 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain JIP_LZII PF16471.5 KFQ95837.1 - 9.7 6.5 18.0 2.2 8.5 3.2 3.5 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II Pkinase_Tyr PF07714.17 KFQ95838.1 - 4.9e-133 442.2 0.0 4.2e-80 268.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFQ95838.1 - 6.2e-69 232.3 0.0 4.3e-46 157.4 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain FERM_F2 PF18377.1 KFQ95838.1 - 1.8e-54 183.2 2.4 4e-54 182.1 2.4 1.6 1 0 0 1 1 1 1 FERM F2 acyl-CoA binding protein-like domain Jak1_Phl PF17887.1 KFQ95838.1 - 3.5e-47 160.0 0.1 6.4e-45 152.7 0.1 2.4 1 1 0 1 1 1 1 Jak1 pleckstrin homology-like domain FERM_F1 PF18379.1 KFQ95838.1 - 4.5e-32 109.9 0.0 1.1e-31 108.7 0.0 1.7 1 0 0 1 1 1 1 FERM F1 ubiquitin-like domain Kinase-like PF14531.6 KFQ95838.1 - 5.7e-05 22.6 0.0 0.58 9.4 0.0 3.4 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 KFQ95838.1 - 0.00017 21.0 0.1 0.037 13.4 0.1 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family SH2 PF00017.24 KFQ95838.1 - 0.0089 16.1 0.0 0.027 14.6 0.0 1.9 1 0 0 1 1 1 1 SH2 domain RIO1 PF01163.22 KFQ95838.1 - 0.017 14.7 0.1 0.68 9.5 0.0 2.4 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 KFQ95838.1 - 0.16 11.9 0.0 0.81 9.6 0.0 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Serum_albumin PF00273.20 KFQ95839.1 - 1.6e-81 272.3 21.7 1.4e-45 155.2 2.3 3.0 3 0 0 3 3 3 3 Serum albumin family VitD-bind_III PF09164.10 KFQ95839.1 - 6.5e-31 106.1 21.0 1.3e-25 89.2 0.7 5.1 5 0 0 5 5 5 4 Vitamin D binding protein, domain III TMF_TATA_bd PF12325.8 KFQ95839.1 - 0.092 13.0 0.4 0.2 11.9 0.1 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding HCO3_cotransp PF00955.21 KFQ95840.1 - 9.6e-238 790.1 8.5 1.2e-237 789.7 8.5 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 KFQ95840.1 - 5.8e-102 341.1 0.1 8.9e-102 340.5 0.1 1.3 1 0 0 1 1 1 1 Band 3 cytoplasmic domain PTS_EIIA_2 PF00359.22 KFQ95840.1 - 0.00034 20.5 0.0 0.0025 17.7 0.0 2.1 2 0 0 2 2 2 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 dNK PF01712.19 KFQ95841.1 - 1.4e-68 230.8 0.7 1.6e-68 230.6 0.7 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_28 PF13521.6 KFQ95841.1 - 0.00029 21.1 0.1 0.0011 19.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KFQ95841.1 - 0.0033 17.1 0.0 0.027 14.2 0.0 2.2 2 1 0 2 2 2 1 Thymidylate kinase AAA_18 PF13238.6 KFQ95841.1 - 0.01 16.4 0.0 0.08 13.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain DUF5066 PF16728.5 KFQ95841.1 - 0.031 13.6 0.1 0.047 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5066) Mob1_phocein PF03637.17 KFQ95842.1 - 7.5e-80 266.9 0.1 9e-80 266.6 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family RUN PF02759.19 KFQ95843.1 - 2.3e-32 111.8 4.7 3.2e-32 111.3 0.0 2.7 2 1 0 2 2 2 1 RUN domain Trimer_CC PF08954.11 KFQ95843.1 - 0.0032 17.0 7.2 0.091 12.3 0.0 3.2 3 0 0 3 3 3 2 Trimerisation motif bZIP_1 PF00170.21 KFQ95843.1 - 0.056 13.5 0.7 0.056 13.5 0.7 5.3 4 1 1 6 6 6 0 bZIP transcription factor ATG16 PF08614.11 KFQ95843.1 - 0.24 11.6 29.7 0.58 10.4 29.7 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 KFQ95843.1 - 0.81 9.5 40.0 0.67 9.7 25.0 2.6 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF1664 PF07889.12 KFQ95843.1 - 3.5 7.7 23.9 0.61 10.1 3.5 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF5595 PF18077.1 KFQ95843.1 - 6.4 6.9 20.1 0.49 10.5 0.9 3.6 4 1 1 5 5 5 0 Domain of unknown function (DUF5595) DUF948 PF06103.11 KFQ95843.1 - 6.6 7.1 13.4 5.4 7.3 1.5 4.0 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Sas10 PF09368.10 KFQ95844.1 - 1.5e-26 92.6 11.6 1.5e-26 92.6 11.6 2.6 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KFQ95844.1 - 3.6e-16 59.5 0.1 3.6e-16 59.5 0.1 2.5 3 1 0 3 3 3 1 Sas10/Utp3/C1D family DUF2247 PF10004.9 KFQ95844.1 - 0.062 13.1 1.1 0.082 12.7 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) TENA_THI-4 PF03070.16 KFQ95844.1 - 0.11 12.3 1.0 0.42 10.4 0.1 2.1 2 0 0 2 2 2 0 TENA/THI-4/PQQC family RST PF12174.8 KFQ95844.1 - 8.9 6.3 10.8 2.9 7.9 0.7 2.7 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain Ig_J_chain PF15097.6 KFQ95845.1 - 1.3e-66 222.5 4.9 1.5e-66 222.3 4.9 1.0 1 0 0 1 1 1 1 Immunoglobulin J chain CBM_5_12 PF02839.14 KFQ95845.1 - 0.053 14.1 0.2 0.1 13.2 0.2 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain Ets PF00178.22 KFQ95846.1 - 5e-23 81.4 0.2 5.8e-23 81.2 0.2 1.1 1 0 0 1 1 1 1 Ets-domain C2 PF00168.30 KFQ95848.1 - 3.6e-09 36.8 0.1 4.6e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.9 KFQ95850.1 - 3.4e-57 192.8 1.5 5.8e-57 192.0 1.5 1.4 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KFQ95850.1 - 9e-14 51.6 0.0 3.2e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 C2 domain PhoLip_ATPase_C PF16212.5 KFQ95851.1 - 7e-83 278.2 29.2 7e-83 278.2 29.2 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFQ95851.1 - 2e-26 91.5 9.3 5.1e-26 90.1 9.3 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFQ95851.1 - 3.5e-12 47.1 0.1 1.9e-05 25.1 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFQ95851.1 - 8.4e-11 41.8 0.0 1.6e-09 37.7 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFQ95851.1 - 2.1e-06 27.4 0.0 7.2e-06 25.6 0.0 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFQ95851.1 - 0.00036 20.4 0.0 0.0013 18.6 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFQ95851.1 - 0.039 14.0 1.6 1 9.4 0.5 2.9 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase ERCC4 PF02732.15 KFQ95853.1 - 1.7e-06 28.3 0.0 9.6e-06 25.9 0.0 2.0 1 1 0 1 1 1 1 ERCC4 domain Catalase-rel PF06628.12 KFQ95853.1 - 0.088 13.0 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 Catalase-related immune-responsive NDK PF00334.19 KFQ95854.1 - 7.6e-56 187.9 0.0 8.6e-56 187.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.18 KFQ95854.1 - 0.025 15.1 0.0 0.042 14.4 0.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ PDEase_I PF00233.19 KFQ95855.1 - 2.1e-69 233.9 3.8 2.1e-69 233.9 3.8 1.6 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase PDE4_UCR PF18100.1 KFQ95855.1 - 1.5e-15 57.9 1.8 2.2e-15 57.3 0.3 2.1 2 0 0 2 2 2 1 Phosphodiesterase 4 upstream conserved regions (UCR) zf-C4 PF00105.18 KFQ95856.1 - 2.3e-33 114.5 12.3 5.4e-33 113.3 12.3 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFQ95856.1 - 6e-24 84.8 1.9 6e-24 84.8 1.9 1.8 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor LSDAT_euk PF18139.1 KFQ95857.1 - 3.1e-120 400.5 0.1 4.5e-120 400.0 0.1 1.2 1 0 0 1 1 1 1 SLOG in TRPM TRPM_tetra PF16519.5 KFQ95857.1 - 2.4e-27 94.8 2.3 8.9e-27 93.0 2.3 2.1 1 0 0 1 1 1 1 Tetramerisation domain of TRPM LSDAT_prok PF18171.1 KFQ95857.1 - 4e-16 58.8 0.1 9.4e-16 57.6 0.1 1.6 1 1 0 1 1 1 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 KFQ95857.1 - 1.1e-12 47.7 16.6 1.9e-12 46.9 16.6 1.4 1 0 0 1 1 1 1 Ion transport protein Tmemb_18A PF09771.9 KFQ95857.1 - 0.035 14.5 0.8 4.3 7.8 0.1 2.8 2 0 0 2 2 2 0 Transmembrane protein 188 N2227 PF07942.12 KFQ95859.1 - 8.8e-112 372.7 0.2 1.1e-111 372.4 0.2 1.1 1 0 0 1 1 1 1 N2227-like protein RhoGAP PF00620.27 KFQ95859.1 - 0.018 14.8 0.4 0.97 9.2 0.3 2.3 1 1 1 2 2 2 0 RhoGAP domain Methyltransf_11 PF08241.12 KFQ95859.1 - 0.031 14.9 0.0 0.07 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KFQ95859.1 - 0.032 15.0 0.0 0.11 13.2 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 KFQ95859.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AAA_18 PF13238.6 KFQ95860.1 - 2.9e-14 53.7 0.0 7.2e-14 52.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFQ95860.1 - 0.0093 16.1 0.0 0.02 15.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain MobB PF03205.14 KFQ95860.1 - 0.01 15.7 0.1 0.042 13.7 0.1 1.8 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.23 KFQ95860.1 - 0.18 11.9 0.1 2.6 8.2 0.1 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase Ank_2 PF12796.7 KFQ95861.1 - 8.2e-19 68.0 0.2 6.7e-13 49.0 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFQ95861.1 - 4.1e-17 62.0 2.5 4.7e-08 33.2 0.1 2.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) SH3_1 PF00018.28 KFQ95861.1 - 2.5e-16 59.0 0.0 4.5e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFQ95861.1 - 8.4e-15 54.4 0.0 1.3e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFQ95861.1 - 2.2e-13 49.7 0.0 5.4e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Ank_4 PF13637.6 KFQ95861.1 - 3.3e-13 49.9 0.7 3.1e-06 27.6 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFQ95861.1 - 4e-11 42.8 0.3 2.3e-05 24.6 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KFQ95861.1 - 4.9e-08 32.6 0.1 1.2 9.9 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ras PF00071.22 KFQ95862.1 - 3e-26 91.9 0.0 3.4e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ95862.1 - 0.00034 20.8 0.0 0.00054 20.2 0.0 1.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ribosomal_L21p PF00829.21 KFQ95863.1 - 3.6e-23 81.8 0.2 1.3e-22 80.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal prokaryotic L21 protein AAA_11 PF13086.6 KFQ95864.1 - 1e-56 192.7 0.3 1e-56 192.7 0.3 3.3 3 1 0 3 3 2 1 AAA domain AAA_12 PF13087.6 KFQ95864.1 - 3.7e-51 173.6 0.0 8.9e-51 172.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 KFQ95864.1 - 2.3e-14 53.6 1.5 2.8e-10 40.3 0.0 3.1 3 1 0 3 3 3 2 AAA domain R3H PF01424.22 KFQ95864.1 - 1.7e-13 50.3 0.1 6.2e-13 48.5 0.1 2.0 2 0 0 2 2 1 1 R3H domain AAA_19 PF13245.6 KFQ95864.1 - 8.4e-12 45.6 0.1 1e-10 42.1 0.1 2.9 2 1 0 2 2 1 1 AAA domain Helicase_RecD PF05127.14 KFQ95864.1 - 3.4e-09 36.8 0.1 0.00054 19.9 0.0 3.5 2 1 0 2 2 2 2 Helicase Viral_helicase1 PF01443.18 KFQ95864.1 - 7.6e-08 32.4 0.6 0.32 10.7 0.0 4.1 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KFQ95864.1 - 1.8e-07 31.4 0.0 5.6e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-AN1 PF01428.16 KFQ95864.1 - 1.2e-06 28.5 11.3 2.5e-06 27.5 11.3 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger AAA_16 PF13191.6 KFQ95864.1 - 0.00027 21.4 0.2 0.0012 19.3 0.2 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFQ95864.1 - 0.00043 20.6 0.1 0.0025 18.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 KFQ95864.1 - 0.0008 19.4 0.1 0.0036 17.3 0.0 2.2 2 0 0 2 2 1 1 Flavivirus DEAD domain DUF2075 PF09848.9 KFQ95864.1 - 0.00095 18.5 0.7 0.029 13.6 0.7 2.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 KFQ95864.1 - 0.0012 18.4 0.0 0.0089 15.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 KFQ95864.1 - 0.0013 18.5 0.2 0.0055 16.5 0.2 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 KFQ95864.1 - 0.0025 17.4 0.0 0.016 14.7 0.0 2.1 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 KFQ95864.1 - 0.0031 16.6 0.0 0.0061 15.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 KFQ95864.1 - 0.0037 17.7 0.4 0.012 16.0 0.4 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KFQ95864.1 - 0.012 15.3 0.0 0.038 13.7 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein VWA_2 PF13519.6 KFQ95864.1 - 0.023 15.3 0.4 2.3 8.9 0.1 3.3 3 0 0 3 3 3 0 von Willebrand factor type A domain AAA_33 PF13671.6 KFQ95864.1 - 0.026 14.7 0.6 0.19 11.9 0.0 2.6 3 0 0 3 3 2 0 AAA domain UvrD_C_2 PF13538.6 KFQ95864.1 - 0.036 13.9 0.0 0.083 12.7 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PIF1 PF05970.14 KFQ95864.1 - 0.04 13.1 0.0 0.35 10.0 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase ABC_tran PF00005.27 KFQ95864.1 - 0.054 14.0 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter DAP3 PF10236.9 KFQ95864.1 - 0.064 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Zot PF05707.12 KFQ95864.1 - 0.092 12.4 0.1 1.1 8.9 0.0 2.7 1 1 2 3 3 3 0 Zonular occludens toxin (Zot) CobA_CobO_BtuR PF02572.15 KFQ95864.1 - 0.098 12.9 0.2 34 4.6 0.0 3.1 3 0 0 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP RL PF17797.1 KFQ95864.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 RL domain PhoH PF02562.16 KFQ95864.1 - 0.11 12.0 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein cobW PF02492.19 KFQ95864.1 - 0.14 11.7 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Herpes_ori_bp PF02399.15 KFQ95864.1 - 0.23 9.4 0.0 0.34 8.9 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein C2 PF00168.30 KFQ95865.1 - 2.3e-21 76.0 0.0 2e-14 53.7 0.0 2.4 2 0 0 2 2 2 2 C2 domain PSS PF03034.15 KFQ95866.1 - 2e-112 375.4 16.0 3.1e-112 374.8 16.0 1.3 1 0 0 1 1 1 1 Phosphatidyl serine synthase HemY_N PF07219.13 KFQ95866.1 - 0.014 15.6 0.1 0.055 13.7 0.1 2.0 1 0 0 1 1 1 0 HemY protein N-terminus Anoctamin PF04547.12 KFQ95867.1 - 3.4e-137 457.9 16.5 4.3e-137 457.6 16.5 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KFQ95867.1 - 2.5e-12 47.0 1.8 1.3e-08 34.9 0.0 2.4 2 0 0 2 2 2 2 Dimerisation domain of Ca+-activated chloride-channel, anoctamin CitMHS PF03600.16 KFQ95867.1 - 0.043 13.0 0.4 0.11 11.7 0.4 1.8 1 1 0 1 1 1 0 Citrate transporter DUF2339 PF10101.9 KFQ95867.1 - 0.13 10.8 4.6 0.046 12.3 0.7 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2339) DUF2207 PF09972.9 KFQ95867.1 - 0.24 10.1 3.3 1.3 7.7 2.9 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) TIR PF01582.20 KFQ95868.1 - 4.2e-19 69.0 0.0 7.7e-19 68.2 0.0 1.4 2 0 0 2 2 2 1 TIR domain TIR_2 PF13676.6 KFQ95868.1 - 1e-08 35.8 0.0 3.1e-08 34.3 0.0 1.7 1 1 1 2 2 2 1 TIR domain Ig_3 PF13927.6 KFQ95868.1 - 9.1e-06 26.2 0.0 2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain BiPBP_C PF06832.12 KFQ95868.1 - 0.096 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family MucB_RseB PF03888.14 KFQ95868.1 - 0.17 11.4 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 MucB/RseB N-terminal domain Arm PF00514.23 KFQ95869.1 - 3.9e-19 68.0 2.1 5.1e-06 26.3 0.0 5.9 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KFQ95869.1 - 0.0033 17.9 0.1 0.23 12.0 0.0 3.5 3 0 0 3 3 3 1 HEAT-like repeat Atx10homo_assoc PF09759.9 KFQ95869.1 - 0.0036 17.3 0.7 0.21 11.6 0.1 3.2 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_C PF11698.8 KFQ95869.1 - 0.079 13.1 0.0 0.3 11.2 0.0 2.0 1 0 0 1 1 1 0 V-ATPase subunit H HEAT_2 PF13646.6 KFQ95869.1 - 0.079 13.4 0.0 0.45 10.9 0.0 2.4 1 1 0 1 1 1 0 HEAT repeats CHGN PF05679.16 KFQ95870.1 - 6.3e-28 97.9 0.0 2.4e-27 96.0 0.0 1.8 1 1 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 KFQ95870.1 - 1.1e-13 50.7 0.8 2e-13 49.8 0.8 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase PA14 PF07691.12 KFQ95870.1 - 9.1e-06 25.5 0.0 2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 PA14 domain CD225 PF04505.12 KFQ95871.1 - 2.7e-21 75.5 0.8 3.9e-21 75.0 0.8 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF4190 PF13828.6 KFQ95871.1 - 0.014 15.1 1.4 0.035 13.9 1.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4190) IncE PF17627.2 KFQ95871.1 - 0.04 13.9 0.3 0.04 13.9 0.3 1.4 2 0 0 2 2 2 0 Inclusion membrane protein E CD225 PF04505.12 KFQ95872.1 - 1.7e-26 92.1 0.3 2.6e-26 91.5 0.3 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein ScdA_N PF04405.14 KFQ95872.1 - 0.081 12.6 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown function (DUF542) Glyco_hydro_65m PF03632.15 KFQ95873.1 - 9.1e-56 189.4 0.1 2.6e-49 168.1 1.3 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain SIR2 PF02146.17 KFQ95874.1 - 3.8e-56 189.8 0.0 4.8e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Ric8 PF10165.9 KFQ95875.1 - 8.1e-135 450.4 2.7 1.7e-134 449.3 1.1 2.1 2 1 0 2 2 2 1 Guanine nucleotide exchange factor synembryn Uteroglobin PF01099.17 KFQ95876.1 - 2.3e-13 50.3 0.0 2.5e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 Uteroglobin family HEAT_EZ PF13513.6 KFQ95876.1 - 0.17 12.4 1.1 5.6 7.6 0.1 2.1 2 0 0 2 2 2 0 HEAT-like repeat INCENP_ARK-bind PF03941.15 KFQ95877.1 - 7.1e-21 73.9 0.2 1.8e-20 72.6 0.2 1.8 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region Tankyrase_bdg_C PF15327.6 KFQ95878.1 - 1.1e-35 123.6 11.4 1.5e-35 123.2 11.4 1.2 1 0 0 1 1 1 1 Tankyrase binding protein C terminal domain POB3_N PF17292.2 KFQ95879.1 - 3.5e-29 101.0 0.5 1.8e-25 89.1 0.2 2.8 2 0 0 2 2 2 2 POB3-like N-terminal PH domain Rtt106 PF08512.12 KFQ95879.1 - 5.3e-28 97.3 0.1 5.6e-27 94.0 0.1 2.5 2 0 0 2 2 2 1 Histone chaperone Rttp106-like SSrecog PF03531.14 KFQ95879.1 - 6e-28 96.6 0.0 1.5e-27 95.2 0.0 1.8 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) HMG_box PF00505.19 KFQ95879.1 - 1e-24 86.7 6.0 1e-24 86.7 6.0 2.8 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFQ95879.1 - 4.8e-13 49.5 5.5 4.8e-13 49.5 5.5 2.8 3 0 0 3 3 3 1 HMG-box domain V-set PF07686.17 KFQ95880.1 - 2.5e-15 56.6 0.1 2.7e-15 56.5 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFQ95880.1 - 1.1e-08 35.6 0.4 1.9e-08 34.7 0.4 1.4 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ95880.1 - 5.2e-05 23.2 0.0 0.00017 21.6 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFQ95880.1 - 5.5e-05 23.3 0.1 0.00014 21.9 0.1 1.6 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFQ95880.1 - 0.00031 21.0 0.2 0.00079 19.7 0.2 1.6 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFQ95881.1 - 1.2e-10 41.5 0.0 1.2e-10 41.5 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFQ95881.1 - 0.0003 21.3 0.0 0.00038 21.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ95881.1 - 0.01 15.9 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin I-set domain V-set PF07686.17 KFQ95882.1 - 2.8e-19 69.3 0.0 3.3e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFQ95882.1 - 7.9e-08 32.8 0.2 1.6e-07 31.8 0.2 1.5 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ95882.1 - 1.3e-05 25.2 0.0 2e-05 24.5 0.0 1.3 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFQ95882.1 - 1.5e-05 25.1 0.1 6.8e-05 23.0 0.1 1.8 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFQ95882.1 - 0.00098 19.4 1.2 0.0043 17.4 1.2 1.8 1 1 0 1 1 1 1 Immunoglobulin domain Receptor_2B4 PF11465.8 KFQ95882.1 - 0.077 13.2 0.0 0.13 12.5 0.0 1.4 1 1 1 2 2 2 0 Natural killer cell receptor 2B4 DUF3426 PF11906.8 KFQ95882.1 - 0.16 12.1 0.1 0.2 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3426) Peptidase_M10 PF00413.24 KFQ95883.1 - 6e-56 188.7 0.0 8.9e-56 188.1 0.0 1.3 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 KFQ95883.1 - 7.6e-48 160.2 13.9 4.5e-12 45.7 0.2 4.4 4 0 0 4 4 4 4 Hemopexin DUF4953 PF16313.5 KFQ95883.1 - 0.0031 16.8 0.2 0.005 16.1 0.2 1.2 1 0 0 1 1 1 1 Met-zincin Astacin PF01400.24 KFQ95883.1 - 0.0044 16.7 0.3 0.94 9.1 0.1 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 KFQ95883.1 - 0.0047 17.4 0.0 0.0076 16.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFQ95883.1 - 0.0088 15.7 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFQ95883.1 - 0.0092 16.1 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M43 PF05572.13 KFQ95883.1 - 0.032 14.1 0.1 0.055 13.4 0.1 1.3 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Kelch_6 PF13964.6 KFQ95883.1 - 0.062 13.6 0.1 0.53 10.6 0.0 2.6 2 0 0 2 2 2 0 Kelch motif SNF5 PF04855.12 KFQ95884.1 - 1e-56 192.4 0.7 9.1e-30 104.2 0.0 2.2 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 DUF1679 PF07914.11 KFQ95884.1 - 0.0039 16.1 0.0 0.0062 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) DER1 PF04511.15 KFQ95885.1 - 8.2e-58 195.5 11.9 9.4e-58 195.3 11.9 1.0 1 0 0 1 1 1 1 Der1-like family Sugar_tr PF00083.24 KFQ95886.1 - 7.3e-51 173.4 1.7 8.6e-51 173.2 1.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFQ95886.1 - 9.3e-20 70.8 4.7 1.2e-19 70.5 4.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily PspC PF04024.12 KFQ95886.1 - 0.063 13.1 1.1 2.8 7.9 0.3 2.6 2 0 0 2 2 2 0 PspC domain Sugar_tr PF00083.24 KFQ95887.1 - 6.7e-32 110.9 10.5 7.5e-32 110.8 10.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFQ95887.1 - 1.2e-16 60.7 3.8 1.4e-16 60.4 3.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3084 PF11283.8 KFQ95887.1 - 0.49 10.4 2.7 0.28 11.2 0.2 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3084) Sugar_tr PF00083.24 KFQ95888.1 - 9.6e-24 84.0 2.4 1.1e-23 83.9 2.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFQ95888.1 - 5.9e-05 22.2 11.3 0.0011 17.9 11.3 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3792 PF12670.7 KFQ95888.1 - 0.31 11.2 12.1 0.62 10.2 12.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) Sugar_tr PF00083.24 KFQ95889.1 - 1.7e-48 165.6 4.4 2.1e-48 165.3 4.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFQ95889.1 - 2.1e-19 69.7 0.6 2.8e-19 69.3 0.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KFQ95889.1 - 0.0021 17.0 2.8 0.0021 17.0 2.8 1.4 2 0 0 2 2 2 1 MFS_1 like family MFS_2 PF13347.6 KFQ95889.1 - 0.48 8.9 4.3 0.18 10.3 1.5 1.8 2 1 0 2 2 2 0 MFS/sugar transport protein Sugar_tr PF00083.24 KFQ95890.1 - 8.8e-37 127.0 3.1 9.7e-37 126.9 3.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFQ95890.1 - 1.8e-06 27.1 6.3 2.9e-06 26.4 6.3 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3792 PF12670.7 KFQ95890.1 - 3 8.0 11.6 5.5 7.2 11.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) MIF PF01187.18 KFQ95891.1 - 8.4e-52 174.3 0.0 9.3e-52 174.2 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) DEAD PF00270.29 KFQ95892.1 - 1.2e-41 142.4 0.1 2.3e-41 141.5 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFQ95892.1 - 5.1e-28 97.6 0.2 4e-26 91.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFQ95892.1 - 1.6e-11 44.5 0.3 4e-11 43.2 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KFQ95892.1 - 0.0014 18.3 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase T4SS-DNA_transf PF02534.14 KFQ95892.1 - 0.0032 16.4 0.0 0.0056 15.5 0.0 1.4 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer AAA_22 PF13401.6 KFQ95892.1 - 0.0069 16.7 0.6 0.65 10.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 KFQ95892.1 - 0.074 13.4 0.0 0.24 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF4800 PF16057.5 KFQ95892.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) IMS_HHH PF11798.8 KFQ95892.1 - 0.13 12.6 0.1 0.36 11.3 0.1 1.8 1 0 0 1 1 1 0 IMS family HHH motif GST_C PF00043.25 KFQ95893.1 - 7.1e-08 32.6 0.0 1.4e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFQ95893.1 - 1.1e-07 32.1 0.0 4e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFQ95893.1 - 8e-06 26.0 0.0 3.5e-05 23.9 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFQ95893.1 - 1.7e-05 25.1 0.0 3.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFQ95893.1 - 4.7e-05 23.3 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFQ95893.1 - 0.00041 20.6 0.0 0.00092 19.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KFQ95893.1 - 0.11 13.0 0.0 0.32 11.6 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFQ95894.1 - 6.1e-07 29.6 0.0 1.3e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFQ95894.1 - 0.00012 22.2 0.0 0.00044 20.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFQ95894.1 - 0.00025 21.3 0.0 0.00058 20.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFQ95894.1 - 0.0011 18.9 0.1 0.0038 17.2 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFQ95894.1 - 0.0019 18.6 0.0 0.004 17.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain T-box PF00907.22 KFQ95895.1 - 1.5e-80 269.8 0.1 2e-80 269.4 0.1 1.2 1 0 0 1 1 1 1 T-box SH3_2 PF07653.17 KFQ95896.1 - 2.3e-24 84.8 0.2 9.1e-13 47.7 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KFQ95896.1 - 2.5e-21 75.0 0.3 4.2e-16 58.3 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH2 PF00017.24 KFQ95896.1 - 3.2e-21 75.2 0.0 6.6e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 KFQ95896.1 - 2.4e-15 56.1 0.1 1e-07 31.6 0.1 2.9 3 0 0 3 3 3 2 Variant SH3 domain hSH3 PF14603.6 KFQ95896.1 - 0.0096 16.3 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 1 Helically-extended SH3 domain Med15 PF09606.10 KFQ95897.1 - 3.6e-182 608.0 162.3 4.9e-182 607.6 162.3 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal mit_SMPDase PF14724.6 KFQ95898.1 - 0 1511.2 4.8 0 1511.0 4.8 1.0 1 0 0 1 1 1 1 Mitochondrial-associated sphingomyelin phosphodiesterase G_glu_transpept PF01019.21 KFQ95899.1 - 8.1e-138 460.4 0.0 9.2e-138 460.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Polysacc_deac_1 PF01522.21 KFQ95899.1 - 0.077 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide deacetylase G_glu_transpept PF01019.21 KFQ95900.1 - 7.3e-178 592.5 0.0 8.3e-178 592.3 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase LSM PF01423.22 KFQ95901.1 - 6.9e-16 57.7 0.2 9.5e-16 57.3 0.2 1.2 1 0 0 1 1 1 1 LSM domain Kringle PF00051.18 KFQ95901.1 - 0.15 12.4 0.1 0.23 11.8 0.1 1.3 1 0 0 1 1 1 0 Kringle domain Guanylate_cyc_2 PF09778.9 KFQ95902.1 - 4.2e-94 313.8 3.5 4.8e-94 313.6 3.5 1.0 1 0 0 1 1 1 1 Guanylylate cyclase Peptidase_C39_2 PF13529.6 KFQ95902.1 - 3.9e-09 37.2 0.1 1.4e-08 35.4 0.1 1.9 1 1 0 1 1 1 1 Peptidase_C39 like family Peptidase_C70 PF12385.8 KFQ95902.1 - 5.3e-07 29.7 0.0 0.027 14.4 0.0 2.6 2 1 0 2 2 2 2 Papain-like cysteine protease AvrRpt2 DUF3335 PF11814.8 KFQ95902.1 - 3e-05 23.6 0.2 0.021 14.3 0.1 2.2 2 0 0 2 2 2 2 Peptidase_C39 like family Peptidase_C39 PF03412.15 KFQ95902.1 - 0.0004 20.2 0.1 0.0064 16.3 0.2 2.4 2 1 0 2 2 2 1 Peptidase C39 family PyocinActivator PF11112.8 KFQ95902.1 - 0.13 12.4 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Pyocin activator protein PrtN TMEM52 PF14979.6 KFQ95902.1 - 0.22 11.4 5.7 0.42 10.5 5.7 1.4 1 0 0 1 1 1 0 Transmembrane 52 CN_hydrolase PF00795.22 KFQ95903.1 - 8.3e-60 202.3 0.0 9.8e-60 202.1 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase 7tm_1 PF00001.21 KFQ95904.1 - 3.5e-47 160.9 15.9 4.1e-47 160.7 15.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFQ95904.1 - 2.5e-08 34.0 8.9 3.5e-08 33.5 8.9 1.3 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KFQ95904.1 - 2.4e-07 30.4 20.7 2.5e-06 27.1 20.7 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFQ95904.1 - 1.3e-06 28.3 16.2 1.3e-06 28.3 16.2 2.3 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx CH PF00307.31 KFQ95905.1 - 1.1e-20 73.8 0.3 5.3e-20 71.6 0.0 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFQ95905.1 - 9.9e-05 22.1 0.0 0.00023 20.9 0.0 1.7 1 0 0 1 1 1 1 CAMSAP CH domain TMF_DNA_bd PF12329.8 KFQ95905.1 - 0.013 15.5 1.8 0.013 15.5 1.8 9.7 8 3 3 11 11 11 0 TATA element modulatory factor 1 DNA binding RhoGAP PF00620.27 KFQ95906.1 - 1.4e-49 167.8 0.3 1e-48 165.0 0.0 2.5 2 0 0 2 2 2 1 RhoGAP domain Bcr-Abl_Oligo PF09036.10 KFQ95906.1 - 2.9e-37 126.5 1.2 2.9e-37 126.5 1.2 2.7 2 0 0 2 2 2 1 Bcr-Abl oncoprotein oligomerisation domain RhoGEF PF00621.20 KFQ95906.1 - 2e-34 119.4 0.9 4.9e-34 118.2 0.9 1.7 1 0 0 1 1 1 1 RhoGEF domain C2 PF00168.30 KFQ95906.1 - 3.5e-07 30.4 0.0 1.1e-06 28.9 0.0 1.8 1 0 0 1 1 1 1 C2 domain PH PF00169.29 KFQ95906.1 - 0.004 17.6 2.8 0.015 15.8 0.7 2.9 2 1 0 2 2 2 1 PH domain IQ_SEC7_PH PF16453.5 KFQ95906.1 - 0.02 14.9 0.0 0.064 13.2 0.0 1.8 1 0 0 1 1 1 0 PH domain Ras PF00071.22 KFQ95907.1 - 4.4e-45 153.2 0.3 5.7e-45 152.8 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ95907.1 - 2.4e-30 105.2 0.0 4.4e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ95907.1 - 3e-15 56.1 0.0 4.1e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFQ95907.1 - 2.7e-07 30.7 0.0 4.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFQ95907.1 - 6.4e-05 22.4 0.0 8.1e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFQ95907.1 - 0.0016 18.0 0.0 0.11 12.0 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 KFQ95907.1 - 0.0084 15.5 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein FeoB_N PF02421.18 KFQ95907.1 - 0.035 13.6 0.0 0.34 10.4 0.0 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.6 KFQ95907.1 - 0.042 13.9 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFQ95907.1 - 0.091 12.7 0.1 3.4 7.5 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 KFQ95908.1 - 3.9e-119 398.0 1.0 4.5e-119 397.7 1.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFQ95908.1 - 1.1e-16 60.8 0.3 7.7e-11 41.7 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFQ95908.1 - 0.00021 20.7 4.3 0.016 14.6 0.4 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFQ95908.1 - 0.0031 17.6 0.3 1.2 9.2 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase TniB PF05621.11 KFQ95908.1 - 0.012 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Roc PF08477.13 KFQ95908.1 - 0.013 15.7 1.4 1.8 8.8 0.2 2.6 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KFQ95908.1 - 0.013 15.2 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2951 PF11166.8 KFQ95908.1 - 0.067 13.4 0.3 14 5.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) AAA_16 PF13191.6 KFQ95908.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Arm PF00514.23 KFQ95909.1 - 1.8e-12 46.8 3.1 1.4e-05 24.9 0.0 4.2 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KFQ95909.1 - 4.5e-11 42.0 4.5 0.023 14.9 0.0 5.1 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 KFQ95909.1 - 1.3e-10 41.5 5.6 9.4e-08 32.3 0.8 3.5 1 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.7 KFQ95909.1 - 1.3e-07 31.8 0.1 0.00034 20.7 0.0 2.1 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KFQ95909.1 - 1.7e-07 31.6 8.7 0.00045 20.6 0.3 5.1 2 2 3 5 5 5 1 HEAT-like repeat Adaptin_N PF01602.20 KFQ95909.1 - 1.8e-06 26.8 0.1 6.9e-06 24.9 0.1 1.7 1 1 1 2 2 2 1 Adaptin N terminal region Proteasom_PSMB PF10508.9 KFQ95909.1 - 0.00038 19.1 0.1 0.3 9.6 0.0 2.0 2 0 0 2 2 2 2 Proteasome non-ATPase 26S subunit RICTOR_N PF14664.6 KFQ95909.1 - 0.00048 19.2 0.3 0.0049 15.9 0.2 2.0 1 1 1 2 2 2 2 Rapamycin-insensitive companion of mTOR, N-term HEAT_PBS PF03130.16 KFQ95909.1 - 0.0042 17.6 1.1 4.8 8.1 0.0 4.1 3 2 1 4 4 3 1 PBS lyase HEAT-like repeat MMS19_N PF14500.6 KFQ95909.1 - 0.012 15.2 0.7 1.7 8.1 0.1 2.7 1 1 2 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Arm_2 PF04826.13 KFQ95909.1 - 0.019 14.4 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Armadillo-like DUF3636 PF12331.8 KFQ95909.1 - 0.024 14.5 0.2 3.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3636) Tti2 PF10521.9 KFQ95909.1 - 0.03 13.9 0.1 8.9 5.8 0.0 2.4 2 0 0 2 2 2 0 Tti2 family Vac14_Fab1_bd PF12755.7 KFQ95909.1 - 0.034 14.8 0.0 6.9 7.3 0.0 2.6 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region RasGEF_N_2 PF14663.6 KFQ95909.1 - 0.043 14.2 0.4 23 5.4 0.0 3.5 1 1 4 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain IFRD PF05004.13 KFQ95909.1 - 0.048 12.7 2.0 1.4 7.9 0.0 2.7 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) CLASP_N PF12348.8 KFQ95909.1 - 0.13 11.8 0.1 5.9 6.4 0.0 2.9 1 1 2 3 3 3 0 CLASP N terminal MMS19_C PF12460.8 KFQ95909.1 - 0.22 10.6 2.1 8.1 5.4 0.1 2.4 2 1 0 2 2 2 0 RNAPII transcription regulator C-terminal SSF PF00474.17 KFQ95910.1 - 2.7e-167 556.7 25.5 4.6e-167 556.0 25.5 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family TadF PF16964.5 KFQ95910.1 - 0.17 11.6 0.8 0.44 10.3 0.0 1.9 2 0 0 2 2 2 0 Putative tight adherence pilin protein F 14-3-3 PF00244.20 KFQ95911.1 - 3.3e-93 311.3 6.7 3.7e-93 311.1 6.7 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF3504 PF12012.8 KFQ95911.1 - 0.08 12.9 0.4 0.14 12.0 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) SIX1_SD PF16878.5 KFQ95912.1 - 1.9e-13 50.9 1.2 2.4e-13 50.6 0.2 1.6 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 KFQ95912.1 - 9.2e-09 35.0 2.8 9.2e-09 35.0 2.8 2.2 3 0 0 3 3 3 1 Homeodomain Homeobox_KN PF05920.11 KFQ95912.1 - 1.2e-06 28.3 0.4 3.1e-06 27.0 0.4 1.7 1 0 0 1 1 1 1 Homeobox KN domain HTH_Tnp_1 PF01527.20 KFQ95912.1 - 0.012 15.9 0.4 0.024 14.9 0.4 1.5 1 0 0 1 1 1 0 Transposase CENP-B_N PF04218.13 KFQ95912.1 - 0.1 12.2 0.1 0.34 10.6 0.0 1.9 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain IML1 PF12257.8 KFQ95913.1 - 8.6e-114 379.5 0.2 1.4e-113 378.7 0.2 1.4 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KFQ95913.1 - 6.7e-10 38.9 0.0 1.6e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FGGY_N PF00370.21 KFQ95913.1 - 0.08 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Tantalus PF15386.6 KFQ95914.1 - 1.3e-24 86.0 3.2 3e-24 84.9 3.2 1.6 1 0 0 1 1 1 1 Drosophila Tantalus-like MTH865 PF07747.11 KFQ95914.1 - 0.11 12.3 0.0 0.57 10.0 0.0 2.2 2 0 0 2 2 2 0 MTH865-like family PS_Dcarbxylase PF02666.15 KFQ95915.1 - 6.8e-68 228.2 0.0 8.6e-68 227.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase EIF4E-T PF10477.9 KFQ95916.1 - 2.4e-155 519.0 20.9 3.3e-154 515.3 20.9 2.4 1 1 0 1 1 1 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E MMR_HSR1_Xtn PF16897.5 KFQ95917.1 - 1.2e-45 153.8 0.4 2.2e-45 153.0 0.4 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KFQ95917.1 - 7.6e-25 86.7 0.1 1.7e-24 85.6 0.1 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KFQ95917.1 - 1.8e-19 69.9 0.1 4.2e-19 68.7 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFQ95917.1 - 1.1e-10 41.3 0.1 1.3e-09 37.8 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 KFQ95917.1 - 0.0035 16.4 0.3 0.024 13.6 0.1 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 KFQ95917.1 - 0.0048 17.0 0.3 2.7 8.0 0.2 2.3 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 KFQ95917.1 - 0.0063 16.1 0.1 4.3 6.8 0.0 3.7 2 2 1 3 3 3 1 Elongation factor Tu GTP binding domain zf-C2H2_4 PF13894.6 KFQ95918.1 - 5.4e-31 104.6 48.4 0.00018 22.1 1.9 8.6 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2 PF00096.26 KFQ95918.1 - 1e-28 98.2 51.2 0.0001 22.6 0.8 8.5 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_assoc3 PF16637.5 KFQ95918.1 - 1.1e-28 99.3 4.6 1.1e-28 99.3 4.6 2.6 4 0 0 4 4 2 1 Putative zinc-finger between two C2H2 zinc-fingers on Patz zf-C2H2_jaz PF12171.8 KFQ95918.1 - 2.2e-15 56.5 25.5 0.0015 18.8 0.6 8.2 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KFQ95918.1 - 1.1e-14 54.1 58.7 3e-06 27.4 2.2 10.2 11 0 0 11 11 10 4 Zinc-finger double domain zf-met PF12874.7 KFQ95918.1 - 1.2e-12 47.8 27.1 0.027 14.9 0.6 8.1 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFQ95918.1 - 1.5e-11 43.9 45.6 1.4e-05 24.9 3.1 8.4 8 0 0 8 8 8 4 C2H2-type zinc finger zf-Di19 PF05605.12 KFQ95918.1 - 3.8e-05 23.9 29.8 0.052 13.8 1.1 5.9 3 1 2 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 KFQ95918.1 - 0.0003 21.5 20.0 0.014 16.1 0.9 5.5 2 2 3 5 5 5 1 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 KFQ95918.1 - 0.00075 19.6 26.5 0.067 13.3 0.5 5.7 4 1 2 6 6 6 3 Zinc ribbon domain zf_UBZ PF18439.1 KFQ95918.1 - 0.0052 16.3 18.5 7.3 6.3 0.1 8.0 8 0 0 8 8 8 1 Ubiquitin-Binding Zinc Finger ROS_MUCR PF05443.11 KFQ95918.1 - 0.012 15.6 0.1 1.5 8.9 0.0 2.8 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein zf-C2H2_8 PF15909.5 KFQ95918.1 - 0.035 14.4 16.0 0.032 14.5 4.7 3.9 3 1 1 4 4 4 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 KFQ95918.1 - 0.038 14.3 26.9 38 4.7 2.5 7.3 3 1 4 7 7 7 0 C2H2 type zinc-finger (2 copies) ARS2 PF04959.13 KFQ95918.1 - 0.047 14.1 0.1 0.047 14.1 0.1 4.3 4 2 1 5 5 5 0 Arsenite-resistance protein 2 DUF629 PF04780.12 KFQ95918.1 - 0.053 12.0 8.3 5.2 5.5 2.4 4.2 3 1 2 5 5 5 0 Protein of unknown function (DUF629) zf_C2H2_13 PF18508.1 KFQ95918.1 - 0.067 12.8 6.3 0.61 9.7 0.1 3.6 3 0 0 3 3 3 0 Zinc finger domain zf-WRNIP1_ubi PF18279.1 KFQ95918.1 - 0.085 13.5 1.5 32 5.5 0.0 4.6 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Zn-C2H2_12 PF18112.1 KFQ95918.1 - 0.57 10.7 0.1 0.57 10.7 0.1 5.4 6 0 0 6 6 6 0 Autophagy receptor zinc finger-C2H2 domain GAGA PF09237.11 KFQ95918.1 - 0.83 9.5 22.6 5.1 7.0 0.5 6.2 6 1 1 7 7 7 0 GAGA factor DZR PF12773.7 KFQ95918.1 - 1.1 9.4 26.3 2.5 8.2 0.2 4.8 4 1 1 5 5 4 0 Double zinc ribbon zf-C2H2_9 PF16293.5 KFQ95918.1 - 2.2 8.2 13.8 1.8 8.4 0.0 5.3 5 1 1 6 6 6 0 C2H2 type zinc-finger (1 copy) DNA_ligase_ZBD PF03119.16 KFQ95918.1 - 4.3 7.5 6.8 32 4.6 0.1 3.3 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain Kringle PF00051.18 KFQ95919.1 - 6.7e-06 26.3 1.2 1.4e-05 25.3 1.2 1.5 1 0 0 1 1 1 1 Kringle domain SDF PF00375.18 KFQ95919.1 - 0.056 12.5 0.0 0.064 12.3 0.0 1.1 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family ABC2_membrane_3 PF12698.7 KFQ95919.1 - 0.11 11.6 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Pkinase_Tyr PF07714.17 KFQ95920.1 - 1.9e-50 171.6 0.0 2.2e-49 168.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ95920.1 - 1.1e-47 162.6 0.0 1.6e-47 162.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LIM PF00412.22 KFQ95920.1 - 4.8e-25 87.6 18.7 1.7e-15 56.9 5.0 2.6 2 0 0 2 2 2 2 LIM domain PDZ PF00595.24 KFQ95920.1 - 2.2e-15 56.8 0.0 3.7e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Kdo PF06293.14 KFQ95920.1 - 9.1e-06 25.2 0.0 1.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PDZ_6 PF17820.1 KFQ95920.1 - 0.00032 20.5 0.1 0.00065 19.5 0.1 1.5 1 0 0 1 1 1 1 PDZ domain APH PF01636.23 KFQ95920.1 - 0.0056 16.6 0.0 0.0098 15.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-RRN7 PF11781.8 KFQ95920.1 - 8 6.3 13.3 0.65 9.7 0.9 2.8 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-C3HC4_3 PF13920.6 KFQ95921.1 - 7.4e-11 41.7 5.4 1e-10 41.3 5.4 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ95921.1 - 1.8e-10 40.5 7.5 2.5e-10 40.0 7.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ95921.1 - 6.5e-10 39.2 9.7 8.8e-10 38.8 9.7 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFQ95921.1 - 3.4e-09 36.4 8.9 5.1e-09 35.8 8.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFQ95921.1 - 2.2e-07 30.6 6.7 3.2e-07 30.1 6.7 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFQ95921.1 - 2.9e-07 30.4 6.4 3.5e-06 26.9 7.3 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFQ95921.1 - 6.4e-07 29.2 6.4 9.3e-07 28.7 6.4 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFQ95921.1 - 8.4e-06 26.0 6.9 1.4e-05 25.3 6.9 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFQ95921.1 - 6.7e-05 22.9 2.3 9.9e-05 22.3 2.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KFQ95921.1 - 0.00049 20.2 7.5 0.00073 19.6 7.5 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 KFQ95921.1 - 0.00058 19.8 2.6 0.00087 19.3 2.6 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.12 KFQ95921.1 - 0.015 14.7 0.1 0.019 14.3 0.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-UDP PF14569.6 KFQ95921.1 - 0.016 15.3 1.6 0.044 13.9 1.6 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 KFQ95921.1 - 0.025 14.3 5.8 0.057 13.2 5.8 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KFQ95921.1 - 0.16 11.6 5.5 0.25 11.0 5.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type IBR PF01485.21 KFQ95921.1 - 0.28 11.4 7.4 0.82 9.9 3.3 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain DUF1272 PF06906.11 KFQ95921.1 - 1.2 9.2 5.3 3.2 7.9 5.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_11 PF17123.5 KFQ95921.1 - 3.2 7.6 9.9 0.32 10.8 5.2 1.8 2 0 0 2 2 2 0 RING-like zinc finger DUF2011 PF09428.10 KFQ95922.1 - 0.022 15.0 0.9 0.34 11.2 0.2 2.2 1 1 1 2 2 2 0 Fungal protein of unknown function (DUF2011) T3SS_needle_E PF08988.10 KFQ95922.1 - 0.044 13.9 0.4 0.2 11.8 0.1 2.1 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle HNF-1B_C PF04812.13 KFQ95923.1 - 2.4e-98 328.7 37.1 3.8e-98 328.1 37.1 1.3 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus HNF-1_N PF04814.13 KFQ95923.1 - 9.5e-59 199.3 0.1 9.5e-59 199.3 0.1 2.8 2 1 1 3 3 3 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Homeodomain PF00046.29 KFQ95923.1 - 6.9e-05 22.6 2.0 0.00068 19.4 2.0 2.4 1 1 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ95923.1 - 0.032 14.1 0.1 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 Homeobox KN domain Peptidase_A22B PF04258.13 KFQ95924.1 - 2.2e-94 316.2 9.1 2.9e-94 315.8 9.1 1.1 1 0 0 1 1 1 1 Signal peptide peptidase GMP_PDE_delta PF05351.11 KFQ95925.1 - 5.7e-77 257.2 1.5 6.4e-77 257.0 1.5 1.0 1 0 0 1 1 1 1 GMP-PDE, delta subunit Malectin PF11721.8 KFQ95926.1 - 5.7e-40 137.1 0.3 5.7e-40 137.1 0.3 1.4 2 0 0 2 2 2 1 Malectin domain Malectin_like PF12819.7 KFQ95926.1 - 0.14 11.3 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Malectin-like domain EF-hand_1 PF00036.32 KFQ95927.1 - 5.7e-31 103.7 15.3 3.6e-10 38.7 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFQ95927.1 - 4.3e-26 91.2 7.3 3.2e-15 56.3 1.0 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFQ95927.1 - 2.1e-25 86.4 6.0 4e-09 35.7 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KFQ95927.1 - 2.3e-20 71.1 11.3 3.1e-08 32.8 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KFQ95927.1 - 4e-20 71.4 13.1 1.8e-12 46.9 0.5 3.7 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 KFQ95927.1 - 4.4e-09 36.5 0.1 0.0039 17.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 KFQ95927.1 - 1.4e-05 25.2 0.1 0.0015 18.7 0.3 2.6 2 1 0 2 2 2 1 Dockerin type I domain SPARC_Ca_bdg PF10591.9 KFQ95927.1 - 2e-05 24.8 0.1 0.0049 17.2 0.0 2.2 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 KFQ95927.1 - 0.00016 21.7 0.2 0.4 10.6 0.0 2.5 2 1 0 2 2 2 2 Tellurite resistance protein TerB EF-hand_4 PF12763.7 KFQ95927.1 - 0.0027 17.6 1.5 0.052 13.5 0.1 2.5 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand POTRA_2 PF08479.11 KFQ95927.1 - 0.0096 15.7 0.0 0.027 14.3 0.0 1.8 1 0 0 1 1 1 1 POTRA domain, ShlB-type DIMCO_N PF16844.5 KFQ95927.1 - 0.0098 16.2 0.1 0.052 13.9 0.0 2.0 2 0 0 2 2 2 1 Dinitrogenase iron-molybdenum cofactor, N-terminal DUF3349 PF11829.8 KFQ95927.1 - 0.018 15.8 0.0 4.8 8.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) Caleosin PF05042.13 KFQ95927.1 - 0.023 14.6 0.0 1.2 9.1 0.0 2.4 2 1 0 2 2 2 0 Caleosin related protein EF-hand_11 PF08976.11 KFQ95927.1 - 0.05 14.5 0.1 1.3 10.0 0.0 2.0 1 1 1 2 2 2 0 EF-hand domain DUF5580 PF17743.1 KFQ95927.1 - 0.094 11.2 0.0 0.75 8.3 0.0 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5580) DUF2666 PF10869.8 KFQ95927.1 - 0.098 12.9 0.1 7.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) RNase_P_Rpp14 PF01900.19 KFQ95928.1 - 5.3e-27 94.1 0.1 7.7e-27 93.6 0.1 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Dynein_light PF01221.18 KFQ95929.1 - 3e-14 53.1 0.0 3.6e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Ubie_methyltran PF01209.18 KFQ95930.1 - 8.6e-89 296.9 0.0 1.1e-88 296.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KFQ95930.1 - 3.3e-17 63.0 0.0 3.7e-15 56.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFQ95930.1 - 6.4e-17 62.0 0.0 1.6e-16 60.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFQ95930.1 - 2.6e-14 53.3 0.0 2.1e-12 47.1 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFQ95930.1 - 3e-09 37.5 0.0 2.8e-08 34.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFQ95930.1 - 5.2e-06 26.4 0.0 7.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KFQ95930.1 - 0.0074 16.2 0.0 0.025 14.4 0.0 1.9 2 0 0 2 2 2 1 Hypothetical methyltransferase UPF0020 PF01170.18 KFQ95930.1 - 0.023 14.4 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Dynein_light PF01221.18 KFQ95931.1 - 2.9e-44 149.3 1.9 3.2e-44 149.1 1.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 UCH PF00443.29 KFQ95931.1 - 0.1 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Dynein_light PF01221.18 KFQ95932.1 - 5.4e-25 87.5 1.1 5.8e-25 87.4 1.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Glu-tRNAGln PF02686.15 KFQ95933.1 - 1.9e-12 47.3 0.1 1.5e-11 44.4 0.0 1.9 1 1 1 2 2 2 1 Glu-tRNAGln amidotransferase C subunit UPF0203 PF05254.12 KFQ95934.1 - 6.2e-12 45.6 0.0 6.7e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX6A PF02046.15 KFQ95935.1 - 2.1e-15 57.1 0.1 4.1e-15 56.2 0.1 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIa RRM_1 PF00076.22 KFQ95936.1 - 5.7e-23 80.5 0.8 2.2e-15 56.2 0.6 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFQ95936.1 - 1e-05 25.6 0.1 0.00046 20.2 0.4 2.6 2 1 0 2 2 2 1 RNA recognition motif PHM7_cyt PF14703.6 KFQ95936.1 - 0.012 15.8 0.2 0.36 11.1 0.1 2.1 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter NID PF07292.13 KFQ95936.1 - 0.086 13.5 0.7 3.5 8.3 0.1 2.2 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) CSD PF00313.22 KFQ95936.1 - 0.22 11.4 1.3 2.8 7.8 0.3 2.3 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain Phospholip_A2_1 PF00068.19 KFQ95937.1 - 2.8e-37 127.6 13.3 3.3e-37 127.4 13.3 1.0 1 0 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.10 KFQ95937.1 - 0.0044 17.2 0.0 0.0077 16.4 0.0 1.4 1 1 0 1 1 1 1 Parvovirus coat protein VP1 Phospholip_A2_2 PF05826.12 KFQ95937.1 - 0.18 12.1 15.8 0.24 11.7 8.9 2.3 1 1 1 2 2 2 0 Phospholipase A2 SIR2 PF02146.17 KFQ95938.1 - 9e-52 175.5 0.0 1.4e-51 174.9 0.0 1.3 1 1 0 1 1 1 1 Sir2 family XPA_N PF01286.18 KFQ95938.1 - 0.015 15.4 2.3 1.4 9.1 0.2 2.4 2 0 0 2 2 2 0 XPA protein N-terminal zf_UBZ PF18439.1 KFQ95938.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C3HC4_3 PF13920.6 KFQ95938.1 - 0.63 9.9 3.4 0.24 11.3 0.5 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-ACC PF17848.1 KFQ95938.1 - 0.67 10.1 2.8 1.6 8.8 0.1 2.5 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain HEAT PF02985.22 KFQ95939.1 - 4.4e-46 150.9 40.8 0.0037 17.4 0.0 25.5 29 0 0 29 29 27 9 HEAT repeat HEAT_2 PF13646.6 KFQ95939.1 - 3.8e-34 116.9 43.7 4.7e-05 23.7 0.0 17.3 15 3 7 22 22 21 9 HEAT repeats HEAT_EZ PF13513.6 KFQ95939.1 - 3.7e-30 103.9 53.5 0.0049 17.3 0.2 23.1 21 6 6 27 27 27 10 HEAT-like repeat CLASP_N PF12348.8 KFQ95939.1 - 4.9e-19 68.8 4.0 0.00051 19.7 0.0 10.5 10 2 1 12 12 12 3 CLASP N terminal Vac14_Fab1_bd PF12755.7 KFQ95939.1 - 3.6e-16 59.5 0.0 0.41 11.3 0.0 10.3 10 1 1 11 11 11 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KFQ95939.1 - 2.6e-15 56.8 18.8 0.22 11.6 0.0 11.4 10 2 2 12 12 12 4 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 KFQ95939.1 - 6.4e-12 45.3 4.5 0.02 14.8 0.0 10.0 11 0 0 11 11 11 2 UME (NUC010) domain MMS19_C PF12460.8 KFQ95939.1 - 6.8e-08 32.0 16.0 0.029 13.5 0.0 8.0 8 3 1 10 10 10 3 RNAPII transcription regulator C-terminal ParcG PF10274.9 KFQ95939.1 - 3.7e-06 27.2 9.6 2.2 8.4 0.0 8.2 10 0 0 10 10 9 2 Parkin co-regulated protein DUF3385 PF11865.8 KFQ95939.1 - 0.00027 20.9 4.0 18 5.2 0.0 7.8 8 0 0 8 8 8 0 Domain of unknown function (DUF3385) RICTOR_M PF14666.6 KFQ95939.1 - 0.0048 16.6 1.3 4.8 7.0 0.1 5.0 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain Condensin2nSMC PF12422.8 KFQ95939.1 - 0.029 14.6 0.7 26 4.9 0.0 4.8 6 0 0 6 6 6 0 Condensin II non structural maintenance of chromosomes subunit CAAP1 PF15335.6 KFQ95939.1 - 0.091 13.3 0.6 2.2 8.9 0.0 3.6 4 0 0 4 4 3 0 Caspase activity and apoptosis inhibitor 1 MA3 PF02847.17 KFQ95939.1 - 3 7.9 6.2 39 4.3 0.3 4.3 3 0 0 3 3 3 0 MA3 domain Arm PF00514.23 KFQ95939.1 - 4.2 7.6 17.2 45 4.3 0.1 8.3 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat Ras PF00071.22 KFQ95940.1 - 4.5e-55 185.7 0.5 6.1e-55 185.2 0.5 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ95940.1 - 2.5e-31 108.4 1.9 2.8e-31 108.2 0.2 1.9 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ95940.1 - 9.4e-16 57.8 0.2 1.3e-15 57.3 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFQ95940.1 - 1.2e-06 28.3 0.4 2e-06 27.5 0.3 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFQ95940.1 - 0.0011 19.0 0.3 0.0019 18.2 0.3 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dioxygenase_N PF04444.14 KFQ95940.1 - 0.091 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Catechol dioxygenase N terminus Glycoprot_B_PH2 PF17417.2 KFQ95940.1 - 0.43 10.9 3.9 2 8.8 0.9 2.3 2 1 0 2 2 2 0 Herpesvirus Glycoprotein B PH-like domain ATG16 PF08614.11 KFQ95941.1 - 3.8e-05 24.0 19.2 3.8e-05 24.0 19.2 3.6 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) AAA_31 PF13614.6 KFQ95941.1 - 6 6.8 7.1 1.4 8.8 1.4 2.5 1 1 2 3 3 3 0 AAA domain CENP-F_leu_zip PF10473.9 KFQ95941.1 - 6.8 6.7 70.5 12 5.9 12.0 5.4 1 1 4 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pkinase PF00069.25 KFQ95942.1 - 9.6e-61 205.4 1.8 1.8e-59 201.3 0.0 3.3 2 1 0 2 2 2 1 Protein kinase domain CNH PF00780.22 KFQ95942.1 - 2e-60 204.7 0.0 4.5e-60 203.6 0.0 1.5 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.17 KFQ95942.1 - 4.5e-29 101.5 0.0 1.3e-28 100.0 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KFQ95942.1 - 6.1e-10 39.6 0.0 2.4e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 PH domain C1_1 PF00130.22 KFQ95942.1 - 2.6e-05 24.0 9.2 5.4e-05 23.0 9.2 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Seadorna_VP7 PF07387.11 KFQ95942.1 - 0.00064 18.9 0.1 0.0021 17.2 0.1 1.8 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 KFQ95942.1 - 0.0016 18.4 0.0 0.0016 18.4 0.0 4.8 5 2 0 5 5 5 1 Phosphotransferase enzyme family Pkinase_C PF00433.24 KFQ95942.1 - 0.0027 18.4 1.6 0.0082 16.8 1.6 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain AMPKBI PF04739.15 KFQ95943.1 - 3.1e-28 97.8 1.8 5.2e-28 97.1 1.8 1.4 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 KFQ95943.1 - 3e-20 72.2 0.1 5.3e-20 71.4 0.1 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DUF4698 PF15769.5 KFQ95944.1 - 1.5e-174 581.7 13.7 1.7e-174 581.5 13.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4698) YdjM PF04307.14 KFQ95944.1 - 0.2 10.9 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase SRRM_C PF15230.6 KFQ95945.1 - 2.5e-27 95.2 29.2 2.5e-27 95.2 29.2 9.6 4 2 4 8 8 8 2 Serine/arginine repetitive matrix protein C-terminus PBP PF01161.20 KFQ95946.1 - 1.9e-17 63.8 0.0 2.3e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein IKBKB_SDD PF18397.1 KFQ95947.1 - 0.009 15.3 0.2 0.01 15.1 0.2 1.2 1 0 0 1 1 1 1 IQBAL scaffold dimerization domain TRP PF06011.12 KFQ95947.1 - 0.16 10.7 0.0 0.17 10.6 0.0 1.0 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Ion_trans PF00520.31 KFQ95948.1 - 7.7e-54 182.5 62.5 1.1e-27 96.9 30.6 2.2 2 0 0 2 2 2 2 Ion transport protein ECSCR PF15820.5 KFQ95948.1 - 0.12 12.3 0.1 0.65 9.9 0.1 2.2 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator Pilin_N PF07790.11 KFQ95948.1 - 0.12 13.3 0.1 0.85 10.6 0.2 2.2 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal Na_Ca_ex PF01699.24 KFQ95949.1 - 5.5e-45 153.0 46.2 2.1e-24 86.2 17.4 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Cyt_c_ox_IV PF12270.8 KFQ95949.1 - 0.048 13.8 0.0 0.048 13.8 0.0 3.2 4 0 0 4 4 4 0 Cytochrome c oxidase subunit IV DUF4870 PF09685.10 KFQ95949.1 - 0.29 11.2 0.1 0.29 11.2 0.1 4.5 4 2 0 4 4 4 0 Domain of unknown function (DUF4870) Phospholip_B PF04916.13 KFQ95950.1 - 4.3e-167 556.9 0.0 4.9e-167 556.7 0.0 1.0 1 0 0 1 1 1 1 Phospholipase B RRM_1 PF00076.22 KFQ95951.1 - 3.8e-87 286.1 5.4 1.7e-19 69.4 0.0 6.4 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFQ95951.1 - 2.7e-08 33.8 7.2 0.29 11.2 0.2 7.4 5 2 2 7 7 7 2 RNA binding motif RRM_7 PF16367.5 KFQ95951.1 - 3.5e-08 33.5 0.1 0.98 9.6 0.0 5.7 6 0 0 6 6 6 2 RNA recognition motif RRM_Rrp7 PF17799.1 KFQ95951.1 - 1.5e-07 31.3 1.3 0.36 10.6 0.0 5.3 5 0 0 5 5 5 2 Rrp7 RRM-like N-terminal domain Limkain-b1 PF11608.8 KFQ95951.1 - 0.00017 21.6 0.1 0.18 11.9 0.0 5.0 5 2 0 5 5 5 1 Limkain b1 Nup35_RRM_2 PF14605.6 KFQ95951.1 - 0.00031 20.7 0.4 26 4.9 0.0 5.0 5 0 0 5 5 5 0 Nup53/35/40-type RNA recognition motif DnaJ-X PF14308.6 KFQ95951.1 - 0.00067 19.2 0.2 0.00067 19.2 0.2 3.8 3 1 0 3 3 3 1 X-domain of DnaJ-containing RRM_occluded PF16842.5 KFQ95951.1 - 0.0017 18.1 0.0 31 4.5 0.0 4.4 5 0 0 5 5 5 0 Occluded RNA-recognition motif T-box PF00907.22 KFQ95952.1 - 4.7e-18 66.1 0.0 2.9e-11 43.9 0.0 2.3 2 0 0 2 2 2 2 T-box T-box PF00907.22 KFQ95953.1 - 3.2e-85 285.0 0.9 9.6e-85 283.5 0.4 1.8 2 0 0 2 2 2 1 T-box TBX PF12598.8 KFQ95953.1 - 1.7e-14 54.3 2.0 1.7e-14 54.3 2.0 2.2 2 0 0 2 2 2 1 T-box transcription factor UCH PF00443.29 KFQ95954.1 - 1.4e-84 283.6 0.2 2e-84 283.1 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_3 PF14836.6 KFQ95954.1 - 2.6e-40 136.3 0.1 5.3e-40 135.3 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain DUSP PF06337.12 KFQ95954.1 - 1.1e-19 70.9 0.9 1.1e-19 70.9 0.9 2.3 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 KFQ95954.1 - 2e-15 57.2 0.1 2.2e-08 34.1 0.0 3.5 3 1 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 KFQ95954.1 - 4.7e-09 36.3 0.7 1.8e-07 31.1 0.0 2.9 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.8 KFQ95954.1 - 0.00032 20.1 0.0 0.0009 18.6 0.0 1.7 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 CW_binding_1 PF01473.20 KFQ95954.1 - 0.054 13.8 4.7 0.32 11.4 4.7 2.3 1 0 0 1 1 1 0 Putative cell wall binding repeat Mon2_C PF16206.5 KFQ95955.1 - 0 1341.3 4.8 0 1340.2 3.8 1.8 2 0 0 2 2 2 1 C-terminal region of Mon2 protein DCB PF16213.5 KFQ95955.1 - 3e-57 193.2 6.1 3e-57 193.2 6.1 2.9 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 KFQ95955.1 - 7.4e-55 185.2 2.4 7.4e-55 185.2 2.4 2.9 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KFQ95955.1 - 8.4e-18 64.0 0.7 8.6e-16 57.6 0.0 4.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) HEAT PF02985.22 KFQ95955.1 - 4.9e-05 23.2 1.3 14 6.3 0.0 5.5 4 0 0 4 4 4 1 HEAT repeat Keratin_assoc PF09775.9 KFQ95955.1 - 0.016 14.9 0.1 0.67 9.6 0.1 2.7 2 0 0 2 2 2 0 Keratinocyte-associated protein 2 SelK_SelG PF10961.8 KFQ95955.1 - 1.6 9.4 3.4 1.1 9.9 0.9 2.1 2 0 0 2 2 2 0 Selenoprotein SelK_SelG RIX1 PF08167.12 KFQ95955.1 - 1.7 8.4 6.4 7 6.3 0.3 4.3 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis PP2C PF00481.21 KFQ95956.1 - 5.8e-27 95.0 0.0 4.5e-12 46.1 0.0 3.0 3 0 0 3 3 3 3 Protein phosphatase 2C SpoIIE PF07228.12 KFQ95956.1 - 0.00019 21.4 0.0 0.23 11.4 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KFQ95956.1 - 0.018 14.7 0.0 0.12 12.0 0.0 2.2 1 1 0 1 1 1 0 Protein phosphatase 2C Exostosin PF03016.15 KFQ95958.1 - 0.00013 21.3 0.0 0.00022 20.6 0.0 1.4 1 0 0 1 1 1 1 Exostosin family PBSX_XtrA PF17356.2 KFQ95958.1 - 0.039 13.9 0.1 0.086 12.8 0.1 1.5 1 0 0 1 1 1 0 Phage-like element PBSX protein XtrA Flg_bbr_C PF06429.13 KFQ95958.1 - 0.058 13.5 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 Flagellar basal body rod FlgEFG protein C-terminal HCO3_cotransp PF00955.21 KFQ95959.1 - 6.5e-89 299.1 3.0 7.2e-89 298.9 3.0 1.0 1 0 0 1 1 1 1 HCO3- transporter family Cytochrom_B_C PF00032.17 KFQ95959.1 - 0.43 10.9 2.7 0.49 10.7 0.1 2.3 2 1 1 3 3 3 0 Cytochrome b(C-terminal)/b6/petD ArfGap PF01412.18 KFQ95960.1 - 1.3e-38 131.7 0.0 2.3e-38 130.8 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ras PF00071.22 KFQ95960.1 - 4.3e-17 62.2 0.0 1.4e-16 60.6 0.0 1.7 2 0 0 2 2 2 1 Ras family PH PF00169.29 KFQ95960.1 - 1.1e-10 41.9 1.1 3e-05 24.5 0.0 3.3 3 0 0 3 3 3 2 PH domain Ank_2 PF12796.7 KFQ95960.1 - 2.8e-08 34.2 0.0 7.1e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFQ95960.1 - 1.3e-06 28.6 0.0 0.052 14.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KFQ95960.1 - 2.1e-06 28.1 0.0 0.0012 19.3 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFQ95960.1 - 0.00016 21.9 0.3 0.0011 19.3 0.1 2.6 4 0 0 4 4 3 1 Ankyrin repeats (many copies) PH_6 PF15406.6 KFQ95960.1 - 0.0025 18.1 0.0 0.0055 17.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Ank_3 PF13606.6 KFQ95960.1 - 0.0065 16.9 0.0 3.8 8.4 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Roc PF08477.13 KFQ95960.1 - 0.027 14.7 0.0 0.099 12.9 0.0 2.0 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PH_11 PF15413.6 KFQ95960.1 - 0.057 13.8 0.1 6.7 7.2 0.0 2.7 3 0 0 3 3 2 0 Pleckstrin homology domain TniB PF05621.11 KFQ95960.1 - 0.21 11.0 0.0 4.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein Ank_2 PF12796.7 KFQ95961.1 - 2.5e-57 191.4 15.0 2.6e-14 53.6 0.0 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 KFQ95961.1 - 9.3e-39 130.2 13.9 7.4e-06 26.2 0.4 7.7 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.6 KFQ95961.1 - 1.3e-34 118.1 4.9 7e-07 29.7 0.1 7.6 3 1 4 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFQ95961.1 - 2.8e-29 100.8 9.6 1.9e-08 34.4 1.1 4.7 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ95961.1 - 6.5e-27 90.6 10.3 0.00023 21.3 0.0 8.6 8 1 0 8 8 8 5 Ankyrin repeat SOCS_box PF07525.16 KFQ95961.1 - 4.5e-07 30.1 4.3 1.1e-06 28.9 4.3 1.7 1 0 0 1 1 1 1 SOCS box Histone PF00125.24 KFQ95962.1 - 4.8e-21 75.5 0.3 5.9e-21 75.2 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFQ95962.1 - 6.6e-06 26.3 0.0 1.2e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1931 PF09123.11 KFQ95962.1 - 0.011 15.9 0.0 0.021 14.9 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1931) YscO-like PF16789.5 KFQ95962.1 - 0.022 14.8 0.0 0.023 14.8 0.0 1.2 1 0 0 1 1 1 0 YscO-like protein TFIID_20kDa PF03847.13 KFQ95962.1 - 0.022 15.2 0.0 0.037 14.5 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A DUF5393 PF17371.2 KFQ95962.1 - 0.046 11.8 0.0 0.05 11.7 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5393) BRI3BP PF14965.6 KFQ95962.1 - 0.069 12.7 0.0 0.079 12.5 0.0 1.1 1 0 0 1 1 1 0 Negative regulator of p53/TP53 ABC_tran PF00005.27 KFQ95963.1 - 3.2e-47 160.5 0.0 1.4e-24 87.1 0.0 2.8 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 KFQ95963.1 - 9e-22 76.9 3.7 9e-22 76.9 3.7 2.6 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.6 KFQ95963.1 - 8.4e-16 58.6 2.3 0.00019 21.3 0.0 4.2 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFQ95963.1 - 6.5e-07 29.0 0.4 0.37 10.2 0.0 3.8 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFQ95963.1 - 5.4e-06 26.0 0.2 0.0045 16.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFQ95963.1 - 6.5e-05 22.9 0.0 0.016 15.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_15 PF13175.6 KFQ95963.1 - 6.5e-05 22.8 2.8 0.028 14.1 0.1 3.4 4 0 0 4 4 4 1 AAA ATPase domain MMR_HSR1 PF01926.23 KFQ95963.1 - 9.3e-05 22.5 0.0 0.018 15.2 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KFQ95963.1 - 0.00012 22.2 0.1 0.12 12.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KFQ95963.1 - 0.00015 22.2 0.0 0.32 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_24 PF13479.6 KFQ95963.1 - 0.0004 20.2 0.2 0.7 9.6 0.0 3.8 4 0 0 4 4 4 1 AAA domain Rop PF01815.16 KFQ95963.1 - 0.0014 18.5 1.9 0.16 11.9 0.1 2.8 2 0 0 2 2 2 1 Rop protein AAA_22 PF13401.6 KFQ95963.1 - 0.0015 18.8 0.0 0.31 11.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KFQ95963.1 - 0.0047 16.9 0.8 1.1 9.2 0.0 2.8 3 0 0 3 3 2 1 NACHT domain AAA_14 PF13173.6 KFQ95963.1 - 0.0057 16.7 0.0 0.97 9.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 KFQ95963.1 - 0.0059 16.9 0.0 0.47 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KFQ95963.1 - 0.01 16.4 10.8 0.015 15.8 0.1 3.6 3 1 0 3 3 3 0 AAA domain AAA PF00004.29 KFQ95963.1 - 0.019 15.4 0.1 1.8 9.0 0.1 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KFQ95963.1 - 0.022 15.3 1.0 0.4 11.2 0.0 3.0 3 1 0 3 3 2 0 AAA domain AAA_27 PF13514.6 KFQ95963.1 - 0.023 14.3 0.6 1.3 8.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KFQ95963.1 - 0.034 13.9 0.0 0.33 10.6 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 KFQ95963.1 - 0.044 13.8 0.2 6.1 6.9 0.2 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KFQ95963.1 - 0.051 14.0 0.0 0.71 10.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 KFQ95963.1 - 0.053 12.7 0.0 6.4 5.9 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Dynamin_N PF00350.23 KFQ95963.1 - 0.085 12.9 0.0 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 Dynamin family IstB_IS21 PF01695.17 KFQ95963.1 - 0.096 12.4 0.0 18 5.0 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein MeaB PF03308.16 KFQ95963.1 - 0.14 11.2 4.7 2.9 6.8 0.0 3.0 4 0 0 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 KFQ95963.1 - 0.14 11.7 0.1 2.5 7.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 KFQ95963.1 - 1.7 8.7 3.6 1.6 8.8 0.0 2.7 3 1 1 4 4 3 0 Helicase HerA, central domain DUF3584 PF12128.8 KFQ95963.1 - 1.8 6.0 7.2 0.43 8.0 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) TMF_TATA_bd PF12325.8 KFQ95963.1 - 5.4 7.3 7.3 2.3 8.4 2.5 2.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding SWIB PF02201.18 KFQ95965.1 - 1.7e-24 85.5 0.2 4.6e-24 84.1 0.2 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain TFIIA PF03153.13 KFQ95966.1 - 3.7 7.5 13.7 4.2 7.3 13.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit COMM_domain PF07258.14 KFQ95967.1 - 4.9e-18 65.0 1.6 4.9e-18 65.0 1.6 1.7 2 0 0 2 2 2 1 COMM domain HTH_1 PF00126.27 KFQ95967.1 - 0.024 14.6 0.4 0.093 12.7 0.1 1.9 1 1 1 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family SOCS PF12610.8 KFQ95967.1 - 0.098 13.1 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 Suppressor of cytokine signalling DUF5057 PF16480.5 KFQ95967.1 - 0.12 11.7 0.3 0.19 11.0 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5057) zf-RING_2 PF13639.6 KFQ95968.1 - 3.1e-13 49.8 8.3 5.3e-13 49.1 8.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFQ95968.1 - 8.7e-12 44.6 3.9 8.7e-12 44.6 3.9 2.3 2 0 0 2 2 2 1 RING-like zinc finger PA PF02225.22 KFQ95968.1 - 3.5e-09 36.6 0.0 7.5e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.6 KFQ95968.1 - 1.1e-08 34.8 8.9 1.9e-08 34.0 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ95968.1 - 1.8e-08 34.1 8.4 3e-08 33.4 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFQ95968.1 - 3.3e-06 26.9 6.9 5.4e-06 26.3 6.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFQ95968.1 - 3.9e-06 26.6 6.3 6.5e-06 25.9 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFQ95968.1 - 1.3e-05 25.4 10.9 7.2e-05 23.0 10.9 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFQ95968.1 - 6.1e-05 23.0 4.4 0.00014 21.8 2.0 2.3 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFQ95968.1 - 0.0014 18.4 6.7 0.0028 17.5 6.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFQ95968.1 - 0.0024 17.9 5.9 0.0069 16.4 5.9 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Neur_chan_memb PF02932.16 KFQ95968.1 - 0.021 14.9 0.0 0.034 14.2 0.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DNA_ligase_ZBD PF03119.16 KFQ95968.1 - 0.079 13.0 0.4 0.17 11.9 0.4 1.6 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Baculo_11_kDa PF06143.11 KFQ95968.1 - 0.099 12.2 1.2 2.4 7.8 0.3 3.0 3 0 0 3 3 3 0 Baculovirus 11 kDa family FeoB_associated PF12669.7 KFQ95968.1 - 0.1 13.0 1.8 0.29 11.6 1.8 1.7 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein PHD PF00628.29 KFQ95968.1 - 0.13 12.2 8.6 0.23 11.4 8.6 1.4 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 KFQ95968.1 - 0.16 11.6 5.1 0.32 10.7 5.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KFQ95968.1 - 0.3 10.9 8.7 0.63 9.9 8.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain STAC2_u1 PF16664.5 KFQ95968.1 - 0.36 11.3 5.3 0.76 10.2 5.3 1.6 1 1 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 RINGv PF12906.7 KFQ95968.1 - 0.99 9.6 7.4 2.2 8.5 7.4 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 KFQ95968.1 - 4.4 7.4 9.3 14 5.8 9.3 1.9 1 1 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 KFQ95968.1 - 7 6.9 9.0 57 4.0 9.0 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Profilin PF00235.19 KFQ95969.1 - 4.4e-13 49.6 0.0 4.8e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Profilin Gag_p30 PF02093.16 KFQ95970.1 - 3e-26 92.3 0.1 3.6e-26 92.0 0.1 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein Gag_p24 PF00607.20 KFQ95970.1 - 0.002 18.0 0.1 0.0048 16.8 0.1 1.6 1 1 0 1 1 1 1 gag gene protein p24 (core nucleocapsid protein) TSC22 PF01166.18 KFQ95971.1 - 4.7e-27 94.1 5.8 5.6e-27 93.8 5.8 1.1 1 0 0 1 1 1 1 TSC-22/dip/bun family YabA PF06156.13 KFQ95971.1 - 0.0019 18.8 3.1 0.0021 18.7 3.1 1.1 1 0 0 1 1 1 1 Initiation control protein YabA K-box PF01486.17 KFQ95971.1 - 0.002 18.3 1.1 0.0026 17.9 1.1 1.3 1 0 0 1 1 1 1 K-box region DivIC PF04977.15 KFQ95971.1 - 0.0058 16.4 3.2 0.0061 16.3 2.7 1.4 1 1 0 1 1 1 1 Septum formation initiator ZapB PF06005.12 KFQ95971.1 - 0.098 13.1 6.8 0.14 12.6 6.8 1.5 1 1 0 1 1 1 0 Cell division protein ZapB eIF2A PF08662.11 KFQ95972.1 - 1.9e-78 262.8 2.2 6.5e-76 254.5 0.1 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A SR-25 PF10500.9 KFQ95972.1 - 0.53 9.9 16.6 0.81 9.3 16.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CRT10 PF08728.10 KFQ95972.1 - 0.57 8.3 3.0 0.82 7.8 3.0 1.2 1 0 0 1 1 1 0 CRT10 Rdx PF10262.9 KFQ95973.1 - 3.2e-11 43.2 0.0 3.9e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Rdx family FAM194 PF14977.6 KFQ95974.1 - 1.2e-58 197.8 0.0 1.4e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 FAM194 protein Sina PF03145.16 KFQ95975.1 - 1.5e-83 279.6 0.1 1.5e-83 279.6 0.1 1.3 2 0 0 2 2 2 1 Seven in absentia protein family zf_C2H2_6 PF18450.1 KFQ95975.1 - 0.26 11.0 3.0 0.77 9.5 3.0 1.9 1 0 0 1 1 1 0 Zinc Finger domain zf-C3HC4_2 PF13923.6 KFQ95975.1 - 0.37 10.7 15.4 0.076 12.9 11.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ95975.1 - 0.7 9.8 9.9 2.4 8.1 9.9 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFQ95975.1 - 0.81 9.6 12.5 11 6.0 11.7 2.8 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-TRAF_2 PF15965.5 KFQ95975.1 - 2.8 8.5 12.0 0.18 12.3 5.5 2.1 1 1 0 1 1 1 0 TRAF-like zinc-finger zf-C3HC4_4 PF15227.6 KFQ95975.1 - 6.4 7.0 14.4 0.46 10.7 8.3 2.3 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF4205 PF13898.6 KFQ95976.1 - 1.1e-36 126.5 0.0 1.2e-36 126.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) Synaptobrevin PF00957.21 KFQ95977.1 - 0.11 12.3 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 Synaptobrevin DUF3671 PF12420.8 KFQ95977.1 - 1.2 9.2 5.4 0.47 10.5 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function Med12-LCEWAV PF12145.8 KFQ95978.1 - 7.6e-183 608.7 0.7 1.3e-182 607.9 0.7 1.4 1 0 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain Med12 PF09497.10 KFQ95978.1 - 9.3e-15 54.7 0.2 2.2e-14 53.5 0.2 1.6 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Nipped-B_C PF12830.7 KFQ95978.1 - 0.12 12.3 0.8 1.7 8.5 0.2 2.9 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus 7tm_1 PF00001.21 KFQ95979.1 - 4.4e-30 104.9 23.2 5.2e-30 104.7 23.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFQ95979.1 - 4.9e-07 29.6 23.0 4.9e-07 29.6 23.0 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Ni_hydr_CYTB PF01292.20 KFQ95979.1 - 0.034 13.7 3.0 0.04 13.5 1.0 2.1 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF92 PF01940.16 KFQ95979.1 - 0.07 12.5 0.5 0.17 11.3 0.5 1.7 1 0 0 1 1 1 0 Integral membrane protein DUF92 OAD_gamma PF04277.13 KFQ95979.1 - 0.086 13.4 0.2 0.086 13.4 0.2 2.2 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain SARAF PF06682.12 KFQ95979.1 - 0.12 12.0 0.7 2.6 7.6 0.1 2.1 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis YtpI PF14007.6 KFQ95979.1 - 0.68 10.1 0.1 0.68 10.1 0.1 3.9 3 1 2 5 5 5 0 YtpI-like protein 7tm_1 PF00001.21 KFQ95980.1 - 6e-37 127.4 21.8 7.1e-37 127.1 21.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFQ95980.1 - 1.6e-06 27.9 21.4 1.6e-06 27.9 21.4 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Alg14 PF08660.11 KFQ95980.1 - 0.03 14.3 1.4 0.05 13.5 0.7 1.7 1 1 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like Phage_holin_4_2 PF04020.13 KFQ95980.1 - 3.3 8.4 15.8 8.8 7.1 3.8 3.5 2 1 1 3 3 3 0 Mycobacterial 4 TMS phage holin, superfamily IV 7tm_1 PF00001.21 KFQ95981.1 - 1.7e-33 116.0 18.7 2e-33 115.8 18.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFQ95981.1 - 0.00014 21.4 15.6 0.0002 20.9 15.6 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv DUF373 PF04123.13 KFQ95981.1 - 0.66 9.4 7.4 0.34 10.3 5.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF373) 7tm_1 PF00001.21 KFQ95982.1 - 1.5e-35 122.8 22.3 1.7e-35 122.6 22.3 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2976 PF11190.8 KFQ95982.1 - 0.014 15.2 1.1 0.054 13.3 1.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) 7tm_1 PF00001.21 KFQ95983.1 - 5.1e-36 124.3 18.6 6.2e-36 124.1 18.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-CCCH PF00642.24 KFQ95984.1 - 3.9e-10 39.4 25.1 0.00024 20.9 1.1 4.9 4 1 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KFQ95984.1 - 6.5e-09 36.0 6.4 4.7e-05 23.6 0.2 2.4 2 0 0 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 KFQ95984.1 - 2.9e-05 23.7 27.7 0.00035 20.3 2.7 4.7 4 1 0 4 4 4 3 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KFQ95984.1 - 5.5e-05 23.5 27.5 0.24 12.0 1.6 4.4 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KFQ95984.1 - 0.00089 19.9 19.0 1.4 9.6 0.3 4.4 2 2 2 4 4 4 4 Torus domain zf_CCCH_4 PF18345.1 KFQ95984.1 - 0.0048 16.9 33.5 0.051 13.6 4.6 6.7 4 4 0 4 4 4 2 Zinc finger domain DUF1936 PF09151.10 KFQ95984.1 - 6.3 6.8 10.4 5.8 6.9 0.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1936) 7tm_1 PF00001.21 KFQ95985.1 - 5.1e-43 147.3 20.3 7.7e-43 146.7 20.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pet100 PF09803.9 KFQ95985.1 - 0.18 12.4 0.9 0.46 11.0 0.9 1.7 1 0 0 1 1 1 0 Pet100 7TM_GPCR_Srx PF10328.9 KFQ95985.1 - 0.97 9.0 25.3 1.3 8.6 20.4 2.3 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Ras PF00071.22 KFQ95986.1 - 5.8e-56 188.6 0.0 6.6e-56 188.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ95986.1 - 4.1e-20 72.2 0.0 5.5e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ95986.1 - 7.2e-10 38.6 0.0 7.7e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFQ95986.1 - 2.8e-06 27.3 0.1 0.0066 16.4 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFQ95986.1 - 7.4e-06 25.6 0.1 8.1e-05 22.2 0.1 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFQ95986.1 - 0.00031 20.8 0.0 0.00046 20.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFQ95986.1 - 0.012 15.2 0.1 0.048 13.2 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 KFQ95986.1 - 0.014 15.4 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain MeaB PF03308.16 KFQ95986.1 - 0.025 13.6 0.1 0.5 9.3 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RhoGEF PF00621.20 KFQ95987.1 - 5.9e-39 134.2 6.0 1.1e-38 133.3 6.0 1.5 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.6 KFQ95987.1 - 2.4e-12 46.5 0.1 5.1e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFQ95987.1 - 4.7e-12 45.3 0.0 1.4e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFQ95987.1 - 8.4e-10 38.2 0.0 2.3e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 KFQ95987.1 - 2.1e-05 25.0 0.0 8.7e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 KFQ95987.1 - 0.00028 20.9 0.4 0.0011 19.0 0.0 2.1 2 0 0 2 2 2 1 PH domain Suppressor_P21 PF11479.8 KFQ95987.1 - 0.048 13.8 1.0 0.28 11.4 0.2 2.5 2 0 0 2 2 2 0 RNA silencing suppressor P21 C-terminal domain PH_13 PF16652.5 KFQ95987.1 - 0.049 13.4 2.0 0.57 10.0 0.4 2.9 2 1 0 2 2 2 0 Pleckstrin homology domain HA2 PF04408.23 KFQ95988.1 - 8.9e-21 74.2 0.0 2.8e-20 72.6 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFQ95988.1 - 2.1e-17 63.2 0.0 4.8e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFQ95988.1 - 1.3e-16 60.9 0.1 3.2e-16 59.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFQ95988.1 - 9.9e-15 54.7 0.1 3.1e-14 53.1 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFQ95988.1 - 1.1e-05 25.8 0.1 3e-05 24.3 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFQ95988.1 - 0.0011 19.4 0.0 0.0052 17.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 KFQ95988.1 - 0.003 16.9 0.0 0.0085 15.5 0.0 1.7 1 0 0 1 1 1 1 KaiC AAA_14 PF13173.6 KFQ95988.1 - 0.015 15.3 0.5 0.38 10.8 0.5 2.8 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KFQ95988.1 - 0.025 15.1 0.1 0.025 15.1 0.1 2.7 1 1 1 2 2 1 0 AAA domain PhoH PF02562.16 KFQ95988.1 - 0.069 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein RsgA_GTPase PF03193.16 KFQ95988.1 - 0.074 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 KFQ95988.1 - 0.16 11.9 0.3 0.76 9.7 0.3 2.3 1 1 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KFQ95988.1 - 0.21 12.0 1.7 0.63 10.4 0.0 2.7 4 0 0 4 4 4 0 AAA ATPase domain ABC_tran PF00005.27 KFQ95988.1 - 0.35 11.4 1.8 0.99 9.9 0.1 2.5 2 1 1 3 3 3 0 ABC transporter Peptidase_M13_N PF05649.13 KFQ95991.1 - 1.2e-120 403.8 2.2 1.7e-120 403.2 2.2 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFQ95991.1 - 4e-72 242.1 0.1 7.8e-72 241.2 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M13 AAA_23 PF13476.6 KFQ95991.1 - 1.2 9.5 7.4 0.19 12.2 2.2 2.0 2 0 0 2 2 2 0 AAA domain PI-PLC-X PF00388.19 KFQ95993.1 - 2.8e-63 211.9 0.0 8.1e-63 210.3 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFQ95993.1 - 1.2e-40 138.4 0.8 3.7e-40 136.9 0.3 2.2 2 0 0 2 2 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 KFQ95993.1 - 1.7e-18 66.9 1.2 4.2e-18 65.6 0.3 2.2 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 KFQ95993.1 - 5.7e-16 58.7 0.0 1.7e-15 57.2 0.0 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.6 KFQ95993.1 - 4.4e-11 43.1 2.7 3e-10 40.4 0.4 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFQ95993.1 - 6.9e-10 37.8 2.4 2.5e-05 23.5 0.0 3.6 3 1 0 3 3 3 2 EF hand EF-hand_10 PF14788.6 KFQ95993.1 - 2.4e-07 30.5 3.2 2.1e-06 27.5 0.2 3.5 3 1 1 4 4 4 2 EF hand EF-hand_6 PF13405.6 KFQ95993.1 - 4.6e-07 29.3 1.0 0.014 15.3 0.0 3.9 3 0 0 3 3 3 2 EF-hand domain PH_12 PF16457.5 KFQ95993.1 - 5.6e-07 30.2 0.0 1.4e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain EF-hand_5 PF13202.6 KFQ95993.1 - 7.6e-06 25.2 2.5 0.0003 20.2 0.1 3.0 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 KFQ95993.1 - 4.7e-05 23.2 1.2 0.07 13.0 0.1 3.0 2 1 1 3 3 3 2 EF-hand domain pair PH PF00169.29 KFQ95993.1 - 0.0011 19.4 0.0 0.0025 18.3 0.0 1.6 1 0 0 1 1 1 1 PH domain EF-hand_4 PF12763.7 KFQ95993.1 - 0.027 14.4 0.1 0.093 12.7 0.1 2.0 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFQ95993.1 - 0.04 14.2 0.1 0.13 12.6 0.1 1.9 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Acatn PF13000.7 KFQ95994.1 - 1.1e-117 393.8 17.6 1.4e-69 235.0 8.2 3.1 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 GATase PF00117.28 KFQ95995.1 - 6.9e-40 136.8 0.0 3.4e-39 134.6 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 KFQ95995.1 - 3.6e-18 65.4 0.0 9.9e-11 41.5 0.0 3.1 2 1 0 2 2 2 2 GMP synthase C terminal domain NAD_synthase PF02540.17 KFQ95995.1 - 8.8e-13 47.9 0.1 6.8e-09 35.2 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KFQ95995.1 - 4.2e-12 46.3 0.1 1.6e-11 44.4 0.1 2.0 1 1 0 1 1 1 1 Peptidase C26 QueC PF06508.13 KFQ95995.1 - 3e-08 33.4 0.1 3e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KFQ95995.1 - 5.6e-06 25.4 0.1 2.1e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 tRNA methyl transferase ATP_bind_3 PF01171.20 KFQ95995.1 - 0.0004 20.2 0.0 0.0008 19.2 0.0 1.5 1 0 0 1 1 1 1 PP-loop family Asn_synthase PF00733.21 KFQ95995.1 - 0.00044 20.0 0.0 0.00072 19.3 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.14 KFQ95995.1 - 0.00074 19.2 0.1 0.0019 17.8 0.1 1.7 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 KFQ95995.1 - 0.0012 19.0 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.19 KFQ95995.1 - 0.0024 17.2 0.0 0.0039 16.5 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase rve PF00665.26 KFQ95995.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain Aldo_ket_red PF00248.21 KFQ95996.1 - 5e-30 104.7 0.0 7.5e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KFQ95997.1 - 1.3e-14 54.1 0.0 1.6e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2685 PF10886.8 KFQ95997.1 - 0.022 15.0 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2685) Ribonuc_red_2_N PF08471.10 KFQ95997.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase TRAP-gamma PF07074.12 KFQ95998.1 - 4.8e-55 185.7 5.6 5.2e-55 185.6 5.6 1.0 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) Renin_r PF07850.14 KFQ95998.1 - 0.016 15.8 1.2 0.025 15.2 0.2 1.7 1 1 0 2 2 2 0 Renin receptor-like protein SPC25 PF06703.11 KFQ95998.1 - 0.075 12.8 3.3 0.048 13.4 1.7 1.5 1 1 1 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) PARP PF00644.20 KFQ95999.1 - 5.2e-35 120.8 4.7 7.4e-34 117.0 4.7 1.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain IFT57 PF10498.9 KFQ96000.1 - 0.0022 17.0 9.4 0.0022 17.0 9.4 2.2 1 1 1 2 2 2 1 Intra-flagellar transport protein 57 OmpH PF03938.14 KFQ96000.1 - 0.014 15.7 9.5 0.014 15.7 9.5 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Ly49 PF08391.10 KFQ96000.1 - 0.014 15.7 6.7 0.014 15.7 6.7 2.8 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region Fib_alpha PF08702.10 KFQ96000.1 - 0.071 13.3 20.0 0.17 12.1 7.2 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family ADIP PF11559.8 KFQ96000.1 - 0.077 13.1 25.1 0.38 10.8 9.2 2.5 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.12 KFQ96000.1 - 0.082 13.4 9.2 3.5 8.2 0.0 3.5 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein HMMR_N PF15905.5 KFQ96000.1 - 0.095 12.2 31.8 0.0095 15.4 23.3 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 KFQ96000.1 - 0.41 9.5 30.5 0.49 9.2 12.6 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein KASH_CCD PF14662.6 KFQ96000.1 - 0.84 9.4 28.1 1.1 9.0 9.8 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH EzrA PF06160.12 KFQ96000.1 - 0.85 7.7 26.7 1.5 6.9 22.9 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF1664 PF07889.12 KFQ96000.1 - 1 9.4 14.8 0.51 10.4 2.9 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 KFQ96000.1 - 1.1 9.7 24.9 5.7 7.3 6.8 2.5 1 1 1 2 2 2 0 Fez1 GAS PF13851.6 KFQ96000.1 - 1.1 8.5 33.7 0.55 9.5 15.1 2.7 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 KFQ96000.1 - 1.1 9.7 28.0 0.087 13.4 10.4 2.6 2 1 0 2 2 2 0 Apg6 coiled-coil region YabA PF06156.13 KFQ96000.1 - 1.4 9.6 25.4 2.7 8.7 3.7 3.7 1 1 1 3 3 3 0 Initiation control protein YabA LMBR1 PF04791.16 KFQ96000.1 - 1.6 7.6 10.7 2 7.3 10.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CENP-F_leu_zip PF10473.9 KFQ96000.1 - 1.6 8.7 32.1 0.025 14.6 13.3 2.7 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 T3SSipB PF16535.5 KFQ96000.1 - 2 8.9 14.4 1.9 9.0 3.0 2.3 1 1 0 2 2 2 0 Type III cell invasion protein SipB KELK PF15796.5 KFQ96000.1 - 3.4 8.2 27.2 1.3 9.6 1.6 4.5 3 2 1 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3450 PF11932.8 KFQ96000.1 - 5.7 6.2 22.4 0.26 10.5 6.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) PKcGMP_CC PF16808.5 KFQ96000.1 - 8.4 6.3 12.7 0.21 11.5 1.2 3.8 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TMF_DNA_bd PF12329.8 KFQ96001.1 - 0.027 14.4 4.4 0.027 14.4 4.4 5.5 2 1 2 6 6 6 0 TATA element modulatory factor 1 DNA binding GAS PF13851.6 KFQ96001.1 - 0.34 10.2 58.9 0.58 9.5 13.5 3.5 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 KFQ96001.1 - 7.4 6.6 30.2 1.5 8.8 5.8 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Cyclin_N PF00134.23 KFQ96002.1 - 1.4e-11 44.3 0.3 8.4e-06 25.5 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFQ96002.1 - 1e-05 25.6 0.1 1e-05 25.6 0.1 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.19 KFQ96002.1 - 0.00044 20.2 0.4 0.24 11.5 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 KFQ96002.1 - 0.0057 17.0 0.1 0.013 15.9 0.1 1.8 1 1 0 1 1 1 1 Cyclin C-terminal domain DUF936 PF06075.12 KFQ96002.1 - 5.7 5.7 28.0 7.4 5.4 28.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) PH PF00169.29 KFQ96003.1 - 7.3e-13 48.9 0.6 2e-12 47.5 0.6 1.8 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KFQ96003.1 - 0.008 16.5 0.6 0.056 13.8 0.6 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFQ96003.1 - 0.011 16.1 3.2 0.011 16.1 3.2 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain PH_3 PF14593.6 KFQ96003.1 - 0.055 13.6 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 PH domain RasGEF PF00617.19 KFQ96003.1 - 0.29 11.3 1.6 3.4 7.8 0.0 3.0 3 1 0 3 3 3 0 RasGEF domain Pentaxin PF00354.17 KFQ96004.1 - 1.1e-27 97.0 0.1 2.6e-27 95.8 0.0 1.6 2 0 0 2 2 2 1 Pentaxin family Laminin_G_3 PF13385.6 KFQ96004.1 - 1.4e-16 61.0 0.1 5.6e-16 59.0 0.0 1.8 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF438 PF04282.13 KFQ96004.1 - 0.0092 15.9 0.2 0.02 14.9 0.2 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF438) PQ-loop PF04193.14 KFQ96005.1 - 2.3e-17 62.5 1.3 2.3e-17 62.5 1.3 2.3 3 0 0 3 3 3 1 PQ loop repeat Homeodomain PF00046.29 KFQ96006.1 - 6.9e-12 45.0 0.2 1e-11 44.5 0.2 1.2 1 0 0 1 1 1 1 Homeodomain Lebercilin PF15619.6 KFQ96006.1 - 0.0047 16.6 0.7 0.0052 16.5 0.7 1.0 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Pro_CA PF00484.19 KFQ96007.1 - 0.2 12.0 1.4 0.58 10.4 1.4 1.8 1 0 0 1 1 1 0 Carbonic anhydrase Mlf1IP PF10248.9 KFQ96008.1 - 2.6e-76 255.4 9.7 3.2e-76 255.1 9.7 1.1 1 0 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein GTP_EFTU PF00009.27 KFQ96009.1 - 1.3e-63 214.1 0.0 1.9e-63 213.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KFQ96009.1 - 4e-36 123.5 0.3 1.6e-35 121.5 0.1 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KFQ96009.1 - 5.7e-25 87.2 0.1 1.4e-24 86.0 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KFQ96009.1 - 9.1e-22 77.0 0.3 9.4e-21 73.7 0.3 2.4 1 1 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KFQ96009.1 - 2.7e-15 56.5 0.0 7.9e-15 55.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KFQ96009.1 - 0.00011 22.0 0.0 0.00047 20.0 0.0 2.0 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 KFQ96009.1 - 0.0018 18.3 0.1 0.0039 17.3 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KFQ96009.1 - 0.017 14.4 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 AIG1 family SRPRB PF09439.10 KFQ96009.1 - 0.14 11.6 0.0 0.45 9.9 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Latexin PF06907.12 KFQ96010.1 - 3.5e-69 232.6 0.9 3.9e-69 232.5 0.9 1.0 1 0 0 1 1 1 1 Latexin Latexin PF06907.12 KFQ96011.1 - 6.2e-74 248.2 0.2 7e-74 248.0 0.2 1.0 1 0 0 1 1 1 1 Latexin MFS_1 PF07690.16 KFQ96012.1 - 1.3e-28 99.9 44.9 9.8e-15 54.3 22.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFQ96012.1 - 1.8e-06 26.8 20.6 1.8e-06 26.8 20.6 2.3 1 1 1 2 2 2 1 MFS/sugar transport protein IQCJ-SCHIP1 PF15157.6 KFQ96013.1 - 1.5e-55 187.3 1.5 1.6e-55 187.2 1.5 1.0 1 0 0 1 1 1 1 Fusion protein IQCJ-SCHIP1 with IQ-like motif CENP-Q PF13094.6 KFQ96013.1 - 0.00072 19.8 1.2 0.001 19.3 1.2 1.2 1 1 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit IQ PF00612.27 KFQ96013.1 - 0.0082 15.8 0.1 0.016 14.9 0.1 1.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif Plasmid_RAQPRD PF09686.10 KFQ96013.1 - 0.079 13.2 1.5 0.11 12.7 1.5 1.2 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) SCHIP-1 PF10148.9 KFQ96014.1 - 1.2e-89 299.9 13.3 1.4e-89 299.8 13.3 1.0 1 0 0 1 1 1 1 Schwannomin-interacting protein 1 FEZ PF07763.13 KFQ96014.1 - 0.00022 21.0 9.3 0.00039 20.2 9.3 1.5 1 1 0 1 1 1 1 FEZ-like protein DUF5102 PF17104.5 KFQ96014.1 - 0.0091 16.1 6.8 0.012 15.6 6.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) EURL PF06937.11 KFQ96014.1 - 0.16 11.4 7.0 0.2 11.0 1.6 2.0 1 1 0 2 2 2 0 EURL protein ABC_tran_Xtn PF12848.7 KFQ96014.1 - 5 7.2 7.4 2.1 8.4 3.8 1.9 2 0 0 2 2 2 0 ABC transporter FIIND PF13553.6 KFQ96015.1 - 3.9e-26 92.0 0.0 4.4e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 Function to find WD40 PF00400.32 KFQ96016.1 - 5.6e-09 36.5 11.6 2 9.4 0.0 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ96016.1 - 1.4e-08 34.9 3.5 0.23 11.8 0.0 5.6 4 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KFQ96016.1 - 0.0061 15.7 1.1 0.035 13.2 1.3 2.3 3 0 0 3 3 3 1 Coatomer WD associated region Ge1_WD40 PF16529.5 KFQ96016.1 - 0.016 14.2 0.0 1.8 7.4 0.0 2.8 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Gp49 PF05973.14 KFQ96016.1 - 0.088 13.0 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Phage derived protein Gp49-like (DUF891) SMC_N PF02463.19 KFQ96017.1 - 8.2e-70 234.7 31.8 2.1e-69 233.3 31.8 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KFQ96017.1 - 5e-23 81.6 2.5 1.8e-22 79.9 0.1 2.9 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 KFQ96017.1 - 3.8e-17 63.0 6.5 3.8e-17 63.0 6.5 4.7 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KFQ96017.1 - 6.9e-12 45.8 3.9 3.8e-05 23.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFQ96017.1 - 0.0002 21.0 0.0 0.00039 20.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain TPR_MLP1_2 PF07926.12 KFQ96017.1 - 0.0034 17.4 19.7 0.0034 17.4 19.7 7.9 4 2 3 8 8 8 3 TPR/MLP1/MLP2-like protein SHNi-TPR PF10516.9 KFQ96017.1 - 0.25 10.8 6.5 1.1 8.8 0.1 3.7 4 0 0 4 4 4 0 SHNi-TPR ABC_tran PF00005.27 KFQ96017.1 - 0.45 11.0 0.0 0.45 11.0 0.0 6.6 3 2 0 4 4 4 0 ABC transporter DUF745 PF05335.13 KFQ96017.1 - 0.66 9.7 86.7 1.6 8.4 11.7 4.8 3 1 1 4 4 4 0 Protein of unknown function (DUF745) Vac_Fusion PF02346.16 KFQ96017.1 - 6.1 6.6 14.4 1.3 8.7 0.0 5.6 4 1 1 5 5 5 0 Chordopoxvirus multifunctional envelope protein A27 zf-RING_UBOX PF13445.6 KFQ96018.1 - 5.5e-11 42.3 6.1 5.5e-11 42.3 6.1 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-B_box PF00643.24 KFQ96018.1 - 2.7e-08 33.8 1.3 2.7e-08 33.8 1.3 3.2 4 0 0 4 4 4 1 B-box zinc finger zf-C3HC4_2 PF13923.6 KFQ96018.1 - 1e-07 31.7 1.9 1e-07 31.7 1.9 2.7 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ96018.1 - 1.2e-07 31.4 6.1 1.2e-07 31.4 6.1 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ96018.1 - 6.9e-07 29.5 7.5 6.9e-07 29.5 7.5 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KFQ96018.1 - 1.8e-06 28.0 5.3 1.8e-06 28.0 5.3 3.0 2 2 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KFQ96018.1 - 4.7e-06 26.5 4.9 4.7e-06 26.5 4.9 2.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFQ96018.1 - 7.3e-06 25.7 5.9 7.3e-06 25.7 5.9 2.8 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFQ96018.1 - 0.00019 21.2 4.7 0.00019 21.2 4.7 2.7 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 U-box PF04564.15 KFQ96018.1 - 0.0034 17.5 0.1 0.035 14.3 0.1 2.4 1 1 0 1 1 1 1 U-box domain zf-RING_6 PF14835.6 KFQ96018.1 - 0.0034 17.2 2.2 0.0034 17.2 2.2 2.4 3 0 0 3 3 3 1 zf-RING of BARD1-type protein DUF1633 PF07794.11 KFQ96018.1 - 0.059 11.6 0.0 0.077 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) Mei5_like PF17021.5 KFQ96018.1 - 0.12 12.4 2.5 0.76 9.8 1.0 2.4 2 0 0 2 2 2 0 Putative double-strand recombination repair-like zf-RING_4 PF14570.6 KFQ96018.1 - 0.23 11.3 4.5 1.3 8.8 4.5 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KFQ96018.1 - 2 8.2 13.1 0.065 13.0 5.7 2.4 2 0 0 2 2 2 0 RING-like zinc finger Arm PF00514.23 KFQ96019.1 - 1.1e-91 298.4 19.0 2.9e-13 49.3 0.2 9.2 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 KFQ96019.1 - 3.4e-25 87.3 3.1 2.6e-23 81.3 3.2 2.5 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 KFQ96019.1 - 4.3e-22 78.2 1.8 4.5e-09 36.6 0.1 6.0 5 1 1 6 6 6 3 HEAT-like repeat HEAT_2 PF13646.6 KFQ96019.1 - 1.7e-19 70.0 0.6 2.8e-06 27.6 0.0 6.7 2 2 6 9 9 9 5 HEAT repeats HEAT PF02985.22 KFQ96019.1 - 1.1e-17 62.6 5.1 0.0034 17.5 0.0 6.8 7 0 0 7 7 7 4 HEAT repeat IBB PF01749.20 KFQ96019.1 - 2.6e-16 59.8 2.6 7.2e-16 58.4 2.6 1.8 1 0 0 1 1 1 1 Importin beta binding domain Adaptin_N PF01602.20 KFQ96019.1 - 7.8e-08 31.3 1.9 5.6e-07 28.5 1.9 2.2 1 1 0 1 1 1 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 KFQ96019.1 - 3.8e-07 30.2 1.0 0.1 12.7 0.1 4.4 4 1 1 5 5 5 3 V-ATPase subunit H Cnd1 PF12717.7 KFQ96019.1 - 2.1e-06 27.9 1.6 0.07 13.2 0.1 3.5 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.14 KFQ96019.1 - 1.1e-05 24.9 1.4 0.00065 19.1 0.5 2.6 1 1 0 2 2 2 1 V-ATPase subunit H Arm_2 PF04826.13 KFQ96019.1 - 8.6e-05 22.1 1.2 0.16 11.4 0.3 3.5 2 1 2 4 4 4 2 Armadillo-like Atx10homo_assoc PF09759.9 KFQ96019.1 - 0.00038 20.4 1.2 0.55 10.3 0.0 4.8 3 1 1 5 5 5 1 Spinocerebellar ataxia type 10 protein domain DRIM PF07539.12 KFQ96019.1 - 0.0048 15.3 0.8 0.78 8.0 0.1 2.4 1 1 1 2 2 2 2 Down-regulated in metastasis RasGEF_N_2 PF14663.6 KFQ96019.1 - 0.011 16.1 0.5 14 6.1 0.0 3.9 3 2 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Mo25 PF08569.11 KFQ96019.1 - 0.046 13.1 0.1 0.12 11.7 0.1 1.6 1 1 0 1 1 1 0 Mo25-like CTNNBL PF08216.11 KFQ96019.1 - 0.093 12.9 4.3 6.9 6.9 0.1 3.9 4 1 0 4 4 4 0 Catenin-beta-like, Arm-motif containing nuclear MMS19_N PF14500.6 KFQ96019.1 - 0.13 11.9 0.0 0.9 9.1 0.0 2.2 1 1 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II DUF4042 PF13251.6 KFQ96019.1 - 0.29 10.8 1.8 2.3 7.9 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) Arf PF00025.21 KFQ96020.1 - 8.9e-59 197.8 0.0 9.8e-59 197.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KFQ96020.1 - 6.4e-15 55.2 2.1 1.9e-11 43.7 0.5 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KFQ96020.1 - 5.5e-13 48.8 0.0 6.2e-13 48.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ96020.1 - 8.5e-13 48.6 0.0 1.2e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFQ96020.1 - 1.1e-08 34.7 0.0 1.3e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFQ96020.1 - 4.6e-08 32.7 0.0 5.6e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFQ96020.1 - 2.4e-06 27.6 0.0 7.1e-06 26.1 0.0 1.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFQ96020.1 - 3.9e-05 23.3 0.0 0.00021 20.9 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KFQ96020.1 - 0.059 12.3 0.0 1.5 7.8 0.0 2.7 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PP2C PF00481.21 KFQ96021.1 - 1.1e-57 195.6 0.0 1.4e-57 195.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFQ96021.1 - 6.3e-08 32.5 0.0 2.4e-07 30.6 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KFQ96021.1 - 0.0021 18.0 0.0 0.17 11.8 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) SPT_ssu-like PF11779.8 KFQ96023.1 - 1.1e-16 60.1 8.6 1.5e-16 59.7 8.6 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Cytomega_US3 PF05963.11 KFQ96023.1 - 0.15 11.7 2.4 0.17 11.5 2.4 1.1 1 0 0 1 1 1 0 Cytomegalovirus US3 protein NMD3 PF04981.13 KFQ96024.1 - 3.2e-81 272.4 6.9 4.7e-81 271.8 6.9 1.3 1 0 0 1 1 1 1 NMD3 family TMEM37 PF15108.6 KFQ96024.1 - 0.017 15.0 0.1 0.032 14.1 0.1 1.4 1 0 0 1 1 1 0 Voltage-dependent calcium channel gamma-like subunit protein family DUF1289 PF06945.13 KFQ96024.1 - 0.23 11.3 3.2 6.1 6.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) DZR PF12773.7 KFQ96024.1 - 2.7 8.1 12.2 51 4.0 12.2 2.8 1 1 0 1 1 1 0 Double zinc ribbon SPT_ssu-like PF11779.8 KFQ96025.1 - 2.5e-15 55.8 7.5 2.7e-15 55.7 7.5 1.0 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like AC_N PF16214.5 KFQ96025.1 - 0.26 10.4 1.1 0.28 10.3 1.1 1.0 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region C1q PF00386.21 KFQ96026.1 - 9.7e-33 113.1 0.0 1.2e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFQ96026.1 - 1.4e-10 40.8 31.6 1.5e-08 34.3 31.6 2.2 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Glyco_hydro_31 PF01055.26 KFQ96028.1 - 4.2e-69 233.8 1.1 4.7e-69 233.7 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Glyco_hydro_66 PF13199.6 KFQ96028.1 - 0.013 14.2 0.1 0.017 13.8 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 GHL15 PF14885.6 KFQ96028.1 - 0.016 15.2 0.5 0.025 14.6 0.5 1.3 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 Pup_ligase PF03136.15 KFQ96028.1 - 0.1 11.6 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Pup-ligase protein ANF_receptor PF01094.28 KFQ96029.1 - 1.1e-10 41.2 0.0 1.4e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region ABM PF03992.16 KFQ96029.1 - 0.14 12.3 0.2 0.34 11.0 0.1 1.7 2 1 0 2 2 2 0 Antibiotic biosynthesis monooxygenase zf-H2C2_2 PF13465.6 KFQ96030.1 - 1.2e-73 240.5 84.4 5.3e-10 39.3 1.6 13.1 12 1 0 12 12 12 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ96030.1 - 3.3e-68 222.5 95.2 1.7e-08 34.4 2.2 13.0 12 1 1 13 13 12 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ96030.1 - 7.9e-35 116.5 88.4 0.0009 19.9 0.4 12.4 12 1 1 13 13 12 11 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFQ96030.1 - 1.2e-22 79.4 65.2 0.0069 16.1 0.2 13.0 12 1 1 13 13 13 8 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KFQ96030.1 - 2e-13 50.2 70.6 0.00039 20.5 1.4 9.0 3 2 8 11 11 10 8 Zinc ribbon domain zf-C2H2_jaz PF12171.8 KFQ96030.1 - 2.6e-11 43.5 30.9 0.63 10.4 0.1 11.0 11 0 0 11 11 11 3 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFQ96030.1 - 1.6e-07 30.8 65.6 0.41 10.3 0.3 12.4 12 1 1 13 13 12 7 Ubiquitin-Binding Zinc Finger FYDLN_acid PF09538.10 KFQ96030.1 - 5.5e-06 27.0 23.8 3.5 8.3 0.0 9.3 2 2 9 11 11 11 1 Protein of unknown function (FYDLN_acid) zf-trcl PF13451.6 KFQ96030.1 - 6.6e-06 25.9 62.4 0.47 10.4 0.0 11.4 8 4 2 10 10 10 4 Probable zinc-ribbon domain zf-C2H2_6 PF13912.6 KFQ96030.1 - 7.3e-06 25.9 84.0 0.18 11.8 0.6 12.5 11 3 0 11 11 11 6 C2H2-type zinc finger DUF3268 PF11672.8 KFQ96030.1 - 4.6e-05 23.7 29.7 0.066 13.5 1.2 6.0 4 1 1 6 6 6 5 zinc-finger-containing domain zf-Di19 PF05605.12 KFQ96030.1 - 0.0017 18.6 2.5 0.0017 18.6 2.5 6.7 4 3 2 7 7 7 1 Drought induced 19 protein (Di19), zinc-binding ADK_lid PF05191.14 KFQ96030.1 - 0.0027 17.6 2.0 0.0027 17.6 2.0 8.5 6 3 2 8 8 8 2 Adenylate kinase, active site lid DNA_RNApol_7kD PF03604.13 KFQ96030.1 - 0.0034 17.0 69.0 0.42 10.3 0.1 12.6 12 1 1 13 13 13 5 DNA directed RNA polymerase, 7 kDa subunit Zn_ribbon_SprT PF17283.2 KFQ96030.1 - 0.0064 16.4 2.2 0.0064 16.4 2.2 9.8 7 3 2 9 9 8 5 SprT-like zinc ribbon domain zinc_ribbon_15 PF17032.5 KFQ96030.1 - 0.064 14.0 48.0 2.5 8.9 0.4 6.9 1 1 6 8 8 8 0 zinc-ribbon family HypA PF01155.19 KFQ96030.1 - 0.19 11.7 48.8 2.8 8.0 0.3 7.1 1 1 3 5 5 5 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FAM209 PF15206.6 KFQ96030.1 - 0.21 11.4 0.1 6.6 6.5 0.0 2.3 2 0 0 2 2 2 0 FAM209 family C1_4 PF07975.12 KFQ96030.1 - 0.75 10.1 50.1 0.84 9.9 0.7 8.6 2 2 5 8 8 8 0 TFIIH C1-like domain DUF3797 PF12677.7 KFQ96030.1 - 1.2 9.1 0.0 1.2 9.1 0.0 7.7 9 2 2 11 11 8 0 Domain of unknown function (DUF3797) XPA_N PF01286.18 KFQ96030.1 - 3.9 7.6 63.3 5.9 7.0 0.1 12.2 12 1 1 13 13 12 0 XPA protein N-terminal HEAT_PBS PF03130.16 KFQ96031.1 - 6.5 7.7 7.8 1e+02 4.1 7.6 2.8 1 1 1 2 2 2 0 PBS lyase HEAT-like repeat zf-H2C2_2 PF13465.6 KFQ96032.1 - 3.6e-65 213.7 75.7 4.7e-10 39.4 2.7 11.4 11 1 0 11 11 11 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ96032.1 - 2.5e-57 188.3 105.7 2.2e-07 31.0 4.5 11.1 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ96032.1 - 1.2e-38 128.4 95.4 4.7e-05 23.9 2.6 11.1 11 0 0 11 11 11 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ96032.1 - 3.8e-14 52.5 48.1 0.069 13.5 0.1 10.7 11 0 0 11 11 11 5 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KFQ96032.1 - 9.7e-11 41.6 55.0 0.001 19.1 2.5 9.0 5 4 5 10 10 10 5 Zinc ribbon domain zf_UBZ PF18439.1 KFQ96032.1 - 5.3e-10 38.7 44.4 0.28 10.8 0.2 10.8 11 0 0 11 11 11 4 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 KFQ96032.1 - 3.8e-08 33.1 80.8 0.0096 15.9 1.1 12.3 11 1 0 11 11 11 5 C2H2-type zinc finger DZR PF12773.7 KFQ96032.1 - 1.1e-06 28.6 38.1 0.22 11.6 0.4 6.2 2 1 1 3 3 2 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 KFQ96032.1 - 2.4e-06 28.2 25.9 0.4 11.5 0.3 5.8 1 1 3 6 6 6 3 zinc-ribbon family zf-C2H2_11 PF16622.5 KFQ96032.1 - 9.7e-06 25.2 74.3 0.2 11.5 0.9 11.1 11 0 0 11 11 11 6 zinc-finger C2H2-type XPA_N PF01286.18 KFQ96032.1 - 2.5e-05 24.2 46.1 3.6 7.7 0.3 10.8 11 0 0 11 11 11 2 XPA protein N-terminal DNA_RNApol_7kD PF03604.13 KFQ96032.1 - 0.00029 20.4 46.7 3.1 7.6 0.1 10.5 11 0 0 11 11 11 3 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 KFQ96032.1 - 0.0009 19.2 28.3 0.94 9.5 3.2 5.8 1 1 3 4 4 4 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FYDLN_acid PF09538.10 KFQ96032.1 - 0.0017 19.0 17.6 7.6 7.3 0.1 8.5 3 3 3 8 8 8 0 Protein of unknown function (FYDLN_acid) zf-trcl PF13451.6 KFQ96032.1 - 0.0044 16.9 45.0 1.4 8.9 0.0 10.4 9 2 0 9 9 9 1 Probable zinc-ribbon domain LIM PF00412.22 KFQ96032.1 - 0.0086 16.3 39.4 1.9 8.8 1.4 9.0 5 4 2 7 7 7 1 LIM domain zf-LYAR PF08790.11 KFQ96032.1 - 0.012 15.5 51.1 3.3 7.7 0.2 11.0 11 0 0 11 11 11 0 LYAR-type C2HC zinc finger DUF2256 PF10013.9 KFQ96032.1 - 0.026 14.6 41.5 0.91 9.7 0.8 10.0 11 0 0 11 11 11 0 Uncharacterized protein conserved in bacteria (DUF2256) YhfH PF14149.6 KFQ96032.1 - 0.04 13.9 37.4 6.4 6.9 0.1 9.8 10 0 0 10 10 10 0 YhfH-like protein DUF2039 PF10217.9 KFQ96032.1 - 0.053 13.9 0.8 0.053 13.9 0.8 4.5 3 2 2 5 5 5 0 Uncharacterized conserved protein (DUF2039) C1_4 PF07975.12 KFQ96032.1 - 0.1 12.8 43.6 4.1 7.7 1.9 8.1 3 3 5 9 9 9 0 TFIIH C1-like domain zf-C2HC_2 PF13913.6 KFQ96032.1 - 0.2 11.6 0.3 0.2 11.6 0.3 10.5 11 1 0 11 11 11 0 zinc-finger of a C2HC-type zf-met PF12874.7 KFQ96032.1 - 0.24 11.9 63.8 6.5 7.3 0.6 10.7 11 0 0 11 11 11 0 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 KFQ96032.1 - 0.3 11.8 34.1 0.86 10.3 0.9 7.7 3 2 2 5 5 5 0 Zinc finger C2H2-type, 3 repeats CpXC PF14353.6 KFQ96032.1 - 0.45 10.6 36.2 10 6.2 1.9 9.3 5 2 3 9 9 9 0 CpXC protein DUF3268 PF11672.8 KFQ96032.1 - 0.49 10.7 33.1 0.54 10.6 0.7 6.1 2 1 5 8 8 8 0 zinc-finger-containing domain TFIIS_C PF01096.18 KFQ96032.1 - 0.91 9.4 41.2 5.2 7.0 0.1 10.4 11 0 0 11 11 11 0 Transcription factor S-II (TFIIS) Zn_ribbon_recom PF13408.6 KFQ96032.1 - 1.1 9.8 64.1 21 5.7 3.4 9.3 4 3 3 7 7 7 0 Recombinase zinc beta ribbon domain Yippee-Mis18 PF03226.14 KFQ96032.1 - 1.2 9.4 23.7 2.9 8.1 0.9 6.5 2 2 2 4 4 4 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-DNA_Pol PF08996.10 KFQ96032.1 - 6.6 6.4 25.0 0.17 11.6 1.3 4.9 3 2 2 5 5 5 0 DNA Polymerase alpha zinc finger F5_F8_type_C PF00754.25 KFQ96033.1 - 1.5e-11 44.5 0.0 1.7e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain Bcl-2 PF00452.19 KFQ96034.1 - 8.4e-28 97.0 0.5 9.5e-28 96.8 0.5 1.0 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family Bclx_interact PF08945.10 KFQ96034.1 - 0.1 12.4 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain Ferritin PF00210.24 KFQ96035.1 - 4.5e-36 123.9 1.7 5.3e-36 123.7 1.7 1.1 1 0 0 1 1 1 1 Ferritin-like domain MOZART1 PF12554.8 KFQ96036.1 - 9e-24 83.0 0.4 1e-23 82.8 0.4 1.0 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Rad50_zn_hook PF04423.14 KFQ96036.1 - 0.041 13.7 0.0 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 Rad50 zinc hook motif CBP_BcsN PF17038.5 KFQ96036.1 - 0.09 12.1 0.1 0.094 12.1 0.1 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsN BORA_N PF15280.6 KFQ96037.1 - 1.1e-69 234.6 4.8 3.7e-69 232.9 4.8 1.9 1 1 0 1 1 1 1 Protein aurora borealis N-terminus Mce4_CUP1 PF11887.8 KFQ96038.1 - 5.9 6.3 8.4 1.4 8.3 0.2 3.0 2 1 1 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative zf-C2H2 PF00096.26 KFQ96039.1 - 9.9e-17 60.4 20.9 5.9e-06 26.4 2.4 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ96039.1 - 8.5e-12 44.9 7.5 1.8e-07 31.3 1.1 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ96039.1 - 7.3e-09 35.7 20.3 0.0017 19.1 2.0 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFQ96039.1 - 0.00065 20.3 4.7 0.1 13.2 0.1 2.7 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-met PF12874.7 KFQ96039.1 - 0.004 17.5 5.7 0.059 13.8 0.6 3.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFQ96039.1 - 0.026 14.5 1.4 0.026 14.5 1.4 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KFQ96039.1 - 0.042 14.0 5.0 1.2 9.2 0.1 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2HC_2 PF13913.6 KFQ96039.1 - 0.13 12.1 0.5 0.38 10.7 0.2 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type IBR PF01485.21 KFQ96039.1 - 0.74 10.1 6.9 3.5 7.9 6.9 2.0 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C2H2_jaz PF12171.8 KFQ96039.1 - 2.8 8.3 7.8 2.5 8.5 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 KFQ96039.1 - 9.2 6.0 6.7 2.3 7.9 0.7 2.9 2 1 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 KFQ96040.1 - 3.9e-16 58.5 23.1 5.4e-06 26.6 2.9 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ96040.1 - 5.9e-11 42.3 9.5 1.3e-07 31.7 1.4 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ96040.1 - 1.3e-06 28.7 20.2 0.051 14.4 1.9 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFQ96040.1 - 0.073 13.5 2.9 7.9 7.0 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFQ96040.1 - 0.081 13.2 3.5 6.3 7.2 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 KFQ96040.1 - 0.12 12.5 2.7 6.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger FOXP-CC PF16159.5 KFQ96040.1 - 0.75 10.5 5.1 5.7 7.7 1.2 2.6 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KFQ96040.1 - 1.3 9.1 9.4 1 9.5 0.9 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KFQ96040.1 - 6.4 6.5 5.5 2.7 7.7 0.3 2.6 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Peptidase_M14 PF00246.24 KFQ96043.1 - 2.1e-56 191.9 0.0 3e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase F5_F8_type_C PF00754.25 KFQ96043.1 - 3.7e-29 101.4 0.1 6.9e-29 100.5 0.1 1.5 1 0 0 1 1 1 1 F5/8 type C domain AstE_AspA PF04952.14 KFQ96043.1 - 0.088 11.9 0.1 0.19 10.8 0.0 1.6 2 0 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family Acetyltransf_1 PF00583.25 KFQ96044.1 - 8e-15 55.1 0.1 2e-14 53.8 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFQ96044.1 - 6e-12 45.6 0.0 9.5e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFQ96044.1 - 8.7e-12 45.3 0.0 1.7e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFQ96044.1 - 2.4e-05 24.4 0.0 4.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KFQ96044.1 - 0.0023 18.0 0.2 0.046 13.8 0.1 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFQ96044.1 - 0.019 14.9 0.2 0.043 13.8 0.2 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_15 PF17013.5 KFQ96044.1 - 0.082 12.4 0.0 0.13 11.8 0.0 1.5 2 0 0 2 2 2 0 Putative acetyl-transferase Acetyltransf_8 PF13523.6 KFQ96044.1 - 0.18 11.5 0.0 0.45 10.2 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Vps16_N PF04841.13 KFQ96045.1 - 5.7e-118 394.2 0.0 7.2e-118 393.9 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 KFQ96045.1 - 7.8e-104 347.2 2.5 1.9e-103 345.9 2.5 1.7 1 1 0 1 1 1 1 Vps16, C-terminal region Iso_dh PF00180.20 KFQ96046.1 - 2e-76 257.4 0.2 2.4e-76 257.1 0.2 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase AAA_3 PF07726.11 KFQ96046.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Dynactin PF12455.8 KFQ96047.1 - 3.6e-47 161.0 1.9 3.6e-47 161.0 1.9 4.7 2 1 1 5 5 5 1 Dynein associated protein TolA_bind_tri PF16331.5 KFQ96047.1 - 0.0046 17.0 11.8 0.0046 17.0 11.8 6.8 4 2 1 6 6 6 2 TolA binding protein trimerisation Filament PF00038.21 KFQ96047.1 - 0.0046 16.6 78.9 0.17 11.4 24.7 3.7 2 1 0 2 2 2 2 Intermediate filament protein Spc7 PF08317.11 KFQ96047.1 - 0.12 11.3 87.2 0.46 9.3 27.5 4.6 1 1 4 5 5 5 0 Spc7 kinetochore protein Phage_GP20 PF06810.11 KFQ96047.1 - 0.18 11.6 73.0 0.12 12.2 18.6 4.9 1 1 2 4 4 4 0 Phage minor structural protein GP20 BRI3BP PF14965.6 KFQ96047.1 - 1.3 8.5 5.8 2.4 7.7 0.0 3.6 3 1 1 4 4 4 0 Negative regulator of p53/TP53 GAS PF13851.6 KFQ96047.1 - 1.5 8.2 92.9 0.2 11.0 26.5 5.5 2 1 3 5 5 5 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 KFQ96047.1 - 8.8 6.7 77.0 0.88 10.0 36.0 3.4 1 1 1 3 3 3 0 Fez1 CAP_GLY PF01302.25 KFQ96048.1 - 4.5e-25 87.5 2.0 5.5e-25 87.2 2.0 1.1 1 0 0 1 1 1 1 CAP-Gly domain adh_short PF00106.25 KFQ96049.1 - 4.3e-34 117.7 0.2 4.8e-33 114.3 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFQ96049.1 - 7.3e-27 94.4 0.2 9.9e-26 90.7 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFQ96049.1 - 3.3e-06 27.2 0.1 5.4e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 KR domain WD40 PF00400.32 KFQ96051.1 - 0.0013 19.5 0.6 30 5.7 0.0 4.4 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ96051.1 - 0.07 13.4 0.0 2.6 8.4 0.0 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 KFQ96051.1 - 0.21 10.8 0.0 7.5 5.7 0.0 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ_3 PF13570.6 KFQ96051.1 - 0.86 10.2 5.4 7.1 7.3 0.1 3.6 3 2 1 4 4 4 0 PQQ-like domain PAPA-1 PF04795.12 KFQ96052.1 - 1.8e-06 28.6 16.5 1.8e-06 28.6 16.5 1.8 2 1 0 2 2 2 1 PAPA-1-like conserved region DUF3619 PF12279.8 KFQ96052.1 - 4.3 7.7 7.1 41 4.5 7.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3619) DUF5571 PF17732.1 KFQ96054.1 - 2.6e-22 79.7 1.0 3.2e-22 79.5 1.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5571) zf-CCCH_3 PF15663.5 KFQ96054.1 - 4.4e-11 43.0 0.0 7.4e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_3 PF15663.5 KFQ96055.1 - 3e-11 43.5 0.0 4.5e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger containing family DUF5571 PF17732.1 KFQ96055.1 - 2.2e-08 34.0 2.4 2.7e-08 33.6 2.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5571) DUF5565 PF17720.1 KFQ96056.1 - 5.2e-159 528.4 0.4 5.8e-159 528.2 0.4 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5565) TPR_2 PF07719.17 KFQ96057.1 - 4.2e-41 135.7 12.0 9.3e-09 34.7 0.1 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ96057.1 - 2.9e-40 133.1 12.3 4.1e-06 26.6 0.0 9.2 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ96057.1 - 5.8e-40 133.5 17.4 4.9e-10 38.8 0.1 9.7 9 0 0 9 9 9 8 Tetratricopeptide repeat DUF1736 PF08409.11 KFQ96057.1 - 7.5e-32 109.1 1.2 1.7e-31 108.0 1.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_17 PF13431.6 KFQ96057.1 - 1.4e-29 100.3 24.0 3.3e-06 27.1 0.3 10.2 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ96057.1 - 8.5e-27 92.6 10.0 2.2e-05 24.1 0.7 8.3 5 3 3 8 8 8 6 TPR repeat TPR_16 PF13432.6 KFQ96057.1 - 2.9e-20 72.6 0.2 7.7e-06 26.5 0.0 5.9 4 1 2 6 6 6 6 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ96057.1 - 2.7e-19 69.4 13.2 7.6e-07 29.6 0.6 6.5 2 1 3 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ96057.1 - 4.4e-19 68.6 13.5 0.00096 19.4 0.0 7.4 5 3 2 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ96057.1 - 4.3e-15 55.1 7.5 0.00017 22.1 0.0 8.2 3 2 5 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFQ96057.1 - 3.1e-10 40.0 0.7 0.00022 21.3 0.2 4.7 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ96057.1 - 1.4e-09 37.3 6.7 3.5 7.9 0.1 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFQ96057.1 - 4.4e-09 36.4 11.8 0.055 14.1 0.1 8.1 9 0 0 9 9 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ96057.1 - 3.6e-08 33.5 3.9 0.066 13.4 0.3 4.6 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KFQ96057.1 - 9.9e-08 31.6 16.3 0.44 10.5 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat ChAPs PF09295.10 KFQ96057.1 - 0.0001 21.4 8.6 0.048 12.7 0.4 2.9 1 1 2 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) Wzy_C_2 PF11846.8 KFQ96057.1 - 0.0067 16.4 0.1 0.0067 16.4 0.1 2.8 4 0 0 4 4 3 1 Virulence factor membrane-bound polymerase, C-terminal PMT_2 PF13231.6 KFQ96057.1 - 0.013 15.7 6.5 0.013 15.7 6.5 2.2 2 1 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase TPR_15 PF13429.6 KFQ96057.1 - 0.05 12.8 9.5 0.039 13.2 4.4 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat ODC_AZ PF02100.17 KFQ96057.1 - 0.088 12.8 0.1 0.23 11.5 0.1 1.7 1 0 0 1 1 1 0 Ornithine decarboxylase antizyme Fis1_TPR_C PF14853.6 KFQ96057.1 - 0.16 12.1 2.3 21 5.3 0.0 4.2 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat DUF2929 PF11151.8 KFQ96057.1 - 0.98 9.8 4.1 0.31 11.3 0.1 2.4 2 0 0 2 2 1 0 Protein of unknown function (DUF2929) SCF PF02404.15 KFQ96058.1 - 1.7e-144 480.2 2.0 1.9e-144 480.0 2.0 1.0 1 0 0 1 1 1 1 Stem cell factor DSPc PF00782.20 KFQ96060.1 - 2.8e-43 146.9 0.0 4e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 KFQ96060.1 - 2.7e-06 27.8 0.0 5.1e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase PF00102.27 KFQ96060.1 - 0.00035 20.2 0.0 0.00052 19.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KFQ96060.1 - 0.014 15.7 0.0 0.023 15.0 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 KFQ96060.1 - 0.09 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate WD40 PF00400.32 KFQ96061.1 - 1.3e-52 174.6 17.6 6.9e-10 39.4 0.0 6.4 7 0 0 7 7 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ96061.1 - 6.6e-22 77.6 0.1 0.0036 17.6 0.0 5.5 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFQ96061.1 - 3e-12 46.2 0.1 0.018 14.0 0.0 5.2 2 2 3 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFQ96061.1 - 2e-08 34.4 0.2 9.4e-06 25.6 0.0 3.4 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KFQ96061.1 - 6e-06 25.2 4.2 2.2 6.8 0.0 4.8 2 2 0 4 4 4 3 Nucleoporin Nup120/160 Proteasome_A_N PF10584.9 KFQ96061.1 - 0.0008 19.0 0.0 1.6 8.5 0.0 3.5 2 0 0 2 2 2 2 Proteasome subunit A N-terminal signature PD40 PF07676.12 KFQ96061.1 - 0.0008 19.3 0.1 3.1 7.9 0.0 4.1 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KFQ96061.1 - 0.00082 18.8 0.0 1.8 7.8 0.0 3.5 2 1 1 4 4 4 2 WD40-like domain Cytochrom_D1 PF02239.16 KFQ96061.1 - 0.0017 17.0 0.0 1.3 7.5 0.0 2.8 1 1 2 3 3 3 2 Cytochrome D1 heme domain CHAP PF05257.16 KFQ96061.1 - 0.03 14.9 0.4 13 6.4 0.0 3.2 3 1 0 4 4 4 0 CHAP domain Frtz PF11768.8 KFQ96061.1 - 0.063 11.6 0.0 18 3.5 0.0 3.2 2 2 2 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF4908 PF16252.5 KFQ96061.1 - 0.11 12.1 0.0 0.29 10.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4908) DUF2527 PF10736.9 KFQ96061.1 - 0.14 12.0 0.7 32 4.5 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) Cation_ATPase_C PF00689.21 KFQ96062.1 - 6.8e-45 153.0 3.8 6.8e-45 153.0 3.8 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KFQ96062.1 - 3.4e-34 117.9 14.7 7.5e-26 90.7 1.5 2.9 3 0 0 3 3 3 2 E1-E2 ATPase ATP_Ca_trans_C PF12424.8 KFQ96062.1 - 1.2e-28 99.4 3.7 2.9e-14 53.3 1.5 2.8 1 1 1 2 2 2 2 Plasma membrane calcium transporter ATPase C terminal Cation_ATPase PF13246.6 KFQ96062.1 - 2e-17 63.1 0.0 4.2e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFQ96062.1 - 3.2e-16 58.8 0.0 1.9e-15 56.3 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KFQ96062.1 - 5.4e-14 53.0 0.2 2.2e-12 47.7 0.2 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFQ96062.1 - 1.2e-05 25.2 5.8 0.00012 21.9 0.4 3.0 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase DUF2201_N PF13203.6 KFQ96062.1 - 0.21 11.1 0.7 0.39 10.3 0.7 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain LRR_8 PF13855.6 KFQ96064.1 - 1.5e-22 79.1 10.3 1.8e-11 43.6 0.8 3.8 3 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFQ96064.1 - 6.6e-10 39.1 16.1 0.015 15.7 0.2 4.6 2 2 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFQ96064.1 - 5e-07 29.7 0.2 0.00011 22.1 0.0 2.6 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFQ96064.1 - 2e-06 27.4 7.7 0.00013 21.5 2.4 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFQ96064.1 - 9.4e-06 25.5 10.3 3.5 8.5 0.2 6.2 6 0 0 6 6 6 2 Leucine Rich Repeat LRRNT PF01462.18 KFQ96064.1 - 2.6e-05 23.7 3.3 2.6e-05 23.7 3.3 2.6 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 KFQ96064.1 - 0.041 13.9 8.7 23 5.4 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich repeat LRR_8 PF13855.6 KFQ96065.1 - 1.5e-32 111.1 32.3 5.3e-09 35.7 2.7 7.0 4 2 1 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 KFQ96065.1 - 6.5e-20 70.9 29.7 5.9e-05 23.3 2.3 7.4 4 3 2 7 7 7 6 Leucine Rich repeats (2 copies) LRRNT PF01462.18 KFQ96065.1 - 2.2e-06 27.2 4.7 6.4e-06 25.7 2.6 2.7 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 KFQ96065.1 - 9e-06 25.3 13.1 0.0039 16.7 1.6 4.1 1 1 2 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 KFQ96065.1 - 1.2e-05 25.0 24.0 1.1 9.4 0.3 7.8 8 0 0 8 8 8 3 Leucine Rich repeat LRR_5 PF13306.6 KFQ96065.1 - 9.9e-05 22.3 2.0 0.0084 16.1 0.7 3.1 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) CRT10 PF08728.10 KFQ96065.1 - 0.035 12.3 0.0 0.052 11.7 0.0 1.2 1 0 0 1 1 1 0 CRT10 LRR_1 PF00560.33 KFQ96065.1 - 0.13 12.9 34.3 6.9 7.6 0.2 10.5 10 2 0 10 10 10 0 Leucine Rich Repeat LRR_8 PF13855.6 KFQ96066.1 - 7.2e-37 125.0 33.9 1.8e-10 40.4 2.1 6.9 3 1 3 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 KFQ96066.1 - 7e-26 89.9 36.7 2.6e-06 27.6 3.3 7.4 2 1 7 9 9 9 9 Leucine Rich repeats (2 copies) LRRNT PF01462.18 KFQ96066.1 - 6.7e-08 32.0 2.3 6.7e-08 32.0 2.3 2.3 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 KFQ96066.1 - 6.9e-08 32.2 9.3 0.011 15.2 0.4 3.4 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 KFQ96066.1 - 2.7e-07 30.2 29.1 7.3 7.6 0.0 10.7 8 3 0 8 8 8 1 Leucine Rich Repeat LRR_5 PF13306.6 KFQ96066.1 - 7.9e-07 29.1 4.1 0.003 17.5 0.1 3.4 2 2 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KFQ96066.1 - 8.6e-07 28.5 36.4 0.017 15.1 0.0 8.6 10 0 0 10 10 10 4 Leucine Rich repeat Rota_NS53 PF00981.17 KFQ96066.1 - 0.055 12.4 0.0 0.092 11.6 0.0 1.3 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) DUF4292 PF14125.6 KFQ96066.1 - 0.27 10.9 2.2 18 4.9 0.0 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF4292) LRR_8 PF13855.6 KFQ96067.1 - 3.5e-36 122.8 21.5 1.2e-13 50.5 3.9 4.4 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFQ96067.1 - 4.4e-23 81.0 24.5 1.7e-05 25.1 3.2 6.4 1 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFQ96067.1 - 1e-12 47.9 4.6 0.00012 21.7 0.0 3.1 1 1 2 3 3 3 3 Leucine-rich repeat LRR_5 PF13306.6 KFQ96067.1 - 9.2e-11 41.8 2.8 2.8e-05 24.1 0.4 3.2 2 1 2 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRRNT PF01462.18 KFQ96067.1 - 3.2e-10 39.4 10.4 3.8e-10 39.2 5.5 3.0 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KFQ96067.1 - 0.00048 20.3 16.0 9 7.3 0.1 7.8 7 1 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.6 KFQ96067.1 - 0.016 15.2 20.2 1.1 9.5 0.0 7.3 8 0 0 8 8 8 0 Leucine Rich repeat GPS2_interact PF15784.5 KFQ96067.1 - 0.13 12.7 0.1 0.25 11.8 0.1 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain FNIP PF05725.12 KFQ96067.1 - 0.34 11.1 6.7 14 6.0 0.1 3.4 2 1 0 2 2 2 0 FNIP Repeat BTG PF07742.12 KFQ96068.1 - 9.5e-31 106.1 0.0 1.2e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 BTG family RhoGEF PF00621.20 KFQ96069.1 - 1.3e-19 71.1 3.6 1.9e-19 70.6 3.3 1.4 1 1 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 KFQ96069.1 - 5.7e-06 26.2 0.8 3.2e-05 23.8 0.2 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_5 PF15405.6 KFQ96069.1 - 0.00017 21.7 0.5 0.0015 18.6 0.4 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_16 PF17838.1 KFQ96069.1 - 0.0075 16.1 0.2 0.025 14.4 0.1 1.9 2 0 0 2 2 2 1 PH domain FYVE PF01363.21 KFQ96070.1 - 3e-20 72.1 10.7 3e-20 72.1 10.7 2.3 2 0 0 2 2 2 1 FYVE zinc finger CENP-F_leu_zip PF10473.9 KFQ96070.1 - 0.00055 20.0 21.9 0.00055 20.0 21.9 14.5 3 3 9 14 14 14 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IBR PF01485.21 KFQ96070.1 - 0.014 15.6 5.3 0.075 13.3 5.3 2.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KFQ96070.1 - 2.2 8.7 11.7 4.2 7.8 9.6 2.4 2 0 0 2 2 2 0 Ring finger domain KNOX2 PF03791.13 KFQ96070.1 - 8.9 5.9 11.0 4.5 6.9 0.3 4.6 3 0 0 3 3 3 0 KNOX2 domain NUDIX PF00293.28 KFQ96071.1 - 2.8e-16 59.7 0.4 3.3e-16 59.5 0.4 1.1 1 0 0 1 1 1 1 NUDIX domain MRP-S32 PF10210.9 KFQ96072.1 - 6.4e-37 126.0 2.6 7.7e-37 125.7 2.6 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S32 SH2 PF00017.24 KFQ96073.1 - 1.4e-13 50.7 0.1 2.1e-13 50.2 0.1 1.3 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.16 KFQ96073.1 - 1.1e-11 44.9 1.8 1.2e-11 44.7 0.7 1.6 2 0 0 2 2 2 1 SOCS box SH2_2 PF14633.6 KFQ96073.1 - 0.00095 18.6 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 SH2 domain Condensation PF00668.20 KFQ96073.1 - 0.016 13.9 0.0 0.021 13.5 0.0 1.1 1 0 0 1 1 1 0 Condensation domain CARD PF00619.21 KFQ96074.1 - 2.4e-16 59.5 0.1 4.1e-16 58.8 0.1 1.4 1 0 0 1 1 1 1 Caspase recruitment domain Death PF00531.22 KFQ96074.1 - 2.9e-13 49.8 0.2 4.9e-12 45.8 0.1 2.2 2 0 0 2 2 2 1 Death domain CARD_2 PF16739.5 KFQ96074.1 - 0.0004 20.3 0.2 0.0012 18.8 0.1 1.8 2 0 0 2 2 2 1 Caspase recruitment domain Tmemb_cc2 PF10267.9 KFQ96075.1 - 1e-160 535.3 11.5 1.2e-160 535.1 11.5 1.0 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein DUF2407_C PF13373.6 KFQ96075.1 - 0.021 15.0 0.2 0.021 15.0 0.2 1.9 2 0 0 2 2 2 0 DUF2407 C-terminal domain VPS11_C PF12451.8 KFQ96075.1 - 0.14 12.4 0.5 0.14 12.4 0.5 3.5 5 0 0 5 5 5 0 Vacuolar protein sorting protein 11 C terminal Exonuc_VII_L PF02601.15 KFQ96075.1 - 0.26 10.8 17.0 0.77 9.3 8.7 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4735 PF15882.5 KFQ96075.1 - 0.99 8.8 10.3 1 8.8 0.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4735) COG2 PF06148.11 KFQ96075.1 - 2.9 8.0 16.2 0.18 11.9 4.5 3.2 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Lipoprotein_20 PF13942.6 KFQ96075.1 - 6.1 6.7 17.4 0.68 9.8 4.5 2.4 2 1 0 2 2 2 0 YfhG lipoprotein FUSC PF04632.12 KFQ96075.1 - 8.6 4.8 8.3 12 4.3 7.5 1.6 1 1 0 1 1 1 0 Fusaric acid resistance protein family NDUFA12 PF05071.16 KFQ96076.1 - 7.9e-30 103.6 3.6 9.3e-30 103.3 3.6 1.0 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Hormone_recep PF00104.30 KFQ96077.1 - 3.3e-44 151.0 1.2 8.9e-44 149.5 0.2 2.0 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFQ96077.1 - 2e-31 108.3 15.6 4.6e-31 107.1 15.6 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF2318 PF10080.9 KFQ96077.1 - 7 6.8 10.3 0.088 12.9 0.6 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) RhoGEF PF00621.20 KFQ96078.1 - 1.2e-36 126.7 4.3 1.3e-36 126.5 2.2 2.3 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.21 KFQ96078.1 - 3.5e-20 71.9 10.2 7.7e-20 70.8 10.2 1.6 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 KFQ96078.1 - 9.7e-18 64.6 2.0 2e-08 34.7 0.0 3.0 3 0 0 3 3 3 2 PH domain PH_13 PF16652.5 KFQ96078.1 - 9.3e-06 25.5 3.4 0.00074 19.4 2.3 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 KFQ96078.1 - 3.4e-05 23.8 1.2 8.7e-05 22.5 0.1 2.1 2 0 0 2 2 2 1 PH domain FYVE_2 PF02318.16 KFQ96078.1 - 0.0022 18.2 8.2 0.0022 18.2 8.2 2.4 3 0 0 3 3 3 1 FYVE-type zinc finger PH_11 PF15413.6 KFQ96078.1 - 0.0029 18.0 4.0 0.12 12.8 0.1 3.8 4 0 0 4 4 4 1 Pleckstrin homology domain PH_9 PF15410.6 KFQ96078.1 - 0.54 10.6 2.2 7.8 6.9 0.8 3.3 2 1 0 2 2 2 0 Pleckstrin homology domain zf-SNAP50_C PF12251.8 KFQ96078.1 - 1.7 8.3 8.8 3.2 7.4 7.9 1.9 1 1 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal zf-B_box PF00643.24 KFQ96078.1 - 7.6 6.8 11.6 23 5.2 11.6 1.9 1 1 0 1 1 1 0 B-box zinc finger Vezatin PF12632.7 KFQ96079.1 - 2.4e-93 312.5 1.1 2.4e-93 312.5 1.1 2.3 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes RNase_3_N PF18497.1 KFQ96079.1 - 0.019 15.2 0.0 5.4 7.3 0.0 3.0 2 0 0 2 2 2 0 Ribonuclease III N-terminal domain YwiC PF14256.6 KFQ96079.1 - 0.029 14.7 3.0 0.051 13.9 3.0 1.3 1 0 0 1 1 1 0 YwiC-like protein DUF2175 PF09943.9 KFQ96079.1 - 0.54 10.6 2.7 7 7.0 0.6 3.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DUF641 PF04859.12 KFQ96079.1 - 0.92 9.9 7.4 0.51 10.7 1.3 2.7 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Peptidase_M24 PF00557.24 KFQ96080.1 - 2.1e-46 158.2 0.0 2.8e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 UCH PF00443.29 KFQ96082.1 - 1.2e-55 188.8 0.0 3.1e-55 187.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFQ96082.1 - 1.5e-20 73.3 8.7 1.5e-20 73.3 8.7 2.8 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KFQ96082.1 - 8.9e-16 58.4 0.4 3.3e-15 56.5 0.4 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Relaxase PF03432.14 KFQ96082.1 - 0.058 13.0 2.3 0.12 11.9 2.3 1.4 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain MPM1 PF17234.2 KFQ96082.1 - 0.16 12.2 5.1 0.37 11.0 5.1 1.5 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 zf-UBP_var PF17807.1 KFQ96082.1 - 1.6 8.6 4.9 0.33 10.7 0.6 2.0 2 0 0 2 2 2 0 Variant UBP zinc finger Laminin_N PF00055.17 KFQ96083.1 - 4.4e-45 154.1 2.3 7e-45 153.4 0.0 2.4 2 1 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 KFQ96083.1 - 1.9e-30 104.8 55.4 1.1e-12 47.8 3.6 5.4 3 1 1 4 4 4 3 Laminin EGF domain NTR PF01759.21 KFQ96083.1 - 2.8e-22 78.6 0.2 5.6e-22 77.6 0.2 1.5 1 0 0 1 1 1 1 UNC-6/NTR/C345C module F5_F8_type_C PF00754.25 KFQ96083.1 - 0.0036 17.4 0.0 0.008 16.3 0.0 1.6 1 0 0 1 1 1 1 F5/8 type C domain LSM PF01423.22 KFQ96084.1 - 1.6e-21 75.7 0.0 2e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFQ96084.1 - 0.054 13.6 0.0 0.063 13.4 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Amidohydro_3 PF07969.11 KFQ96085.1 - 4e-24 85.9 0.8 2.1e-16 60.5 0.0 2.9 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KFQ96085.1 - 6.9e-23 81.5 2.4 1.7e-21 77.0 2.4 2.2 1 1 0 1 1 1 1 Amidohydrolase family Lyase_aromatic PF00221.19 KFQ96086.1 - 2.3e-194 646.4 0.1 2.7e-194 646.2 0.1 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Par3_HAL_N_term PF12053.8 KFQ96086.1 - 5e-05 23.4 0.0 0.00015 21.9 0.0 1.8 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins Peptidase_M1 PF01433.20 KFQ96087.1 - 2.9e-47 161.1 0.0 4.8e-47 160.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KFQ96087.1 - 1.6e-37 128.0 0.0 3.2e-37 127.1 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KFQ96087.1 - 3.9e-21 76.1 0.1 5.4e-21 75.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M48 PF01435.18 KFQ96087.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M48 E1_DerP2_DerF2 PF02221.15 KFQ96087.1 - 0.14 12.6 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 ML domain Ets PF00178.22 KFQ96088.1 - 1.8e-34 118.0 3.0 3.2e-34 117.2 3.0 1.4 1 0 0 1 1 1 1 Ets-domain Translat_reg PF01818.17 KFQ96088.1 - 0.047 13.7 0.0 0.13 12.2 0.0 1.7 1 1 0 1 1 1 0 Bacteriophage translational regulator DUF3399 PF11879.8 KFQ96088.1 - 0.43 10.9 0.1 0.43 10.9 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3399) Pkinase PF00069.25 KFQ96089.1 - 1.5e-72 244.2 0.0 2.8e-72 243.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ96089.1 - 5.3e-35 120.9 0.0 1.1e-34 119.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFQ96089.1 - 5e-07 29.0 0.1 2.4e-06 26.8 0.1 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFQ96089.1 - 2.9e-06 26.8 0.0 6.6e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFQ96089.1 - 0.00028 20.3 0.3 0.00072 19.0 0.3 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KFQ96089.1 - 0.056 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KFQ96089.1 - 0.07 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFQ96089.1 - 0.12 11.1 0.2 3 6.5 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase DUF4486 PF14858.6 KFQ96090.1 - 4.2e-274 910.1 4.4 4.9e-274 909.9 4.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4486) Dynein_heavy PF03028.15 KFQ96091.1 - 0.044 13.9 0.5 0.61 10.2 0.2 2.9 3 0 0 3 3 3 0 Dynein heavy chain region D6 P-loop domain TPR_12 PF13424.6 KFQ96091.1 - 0.074 13.3 2.4 12 6.3 0.2 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ96091.1 - 0.11 12.6 2.8 1.7 8.9 0.6 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3736 PF12540.8 KFQ96093.1 - 0.051 13.7 0.1 0.051 13.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3736) LEM PF03020.15 KFQ96094.1 - 2e-19 68.9 0.3 3.9e-19 67.9 0.3 1.5 1 0 0 1 1 1 1 LEM domain PBP1_TM PF14812.6 KFQ96094.1 - 5.8 7.4 7.3 9.3 6.7 0.0 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mito_carr PF00153.27 KFQ96095.1 - 1.7e-46 156.0 9.0 2e-19 69.3 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Snapin_Pallidin PF14712.6 KFQ96096.1 - 0.00044 20.6 15.5 0.071 13.5 1.4 4.8 4 1 0 4 4 4 1 Snapin/Pallidin DUF148 PF02520.17 KFQ96096.1 - 0.013 15.6 2.4 0.013 15.6 2.4 3.3 2 1 1 4 4 4 0 Domain of unknown function DUF148 Sec8_exocyst PF04048.14 KFQ96096.1 - 0.014 15.3 1.1 0.014 15.3 1.1 2.7 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain COG5 PF10392.9 KFQ96096.1 - 0.018 15.2 14.6 1.4 9.1 2.9 3.9 1 1 2 3 3 3 0 Golgi transport complex subunit 5 DUF4446 PF14584.6 KFQ96096.1 - 0.046 13.7 13.9 0.97 9.4 3.3 4.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) NPV_P10 PF05531.12 KFQ96096.1 - 0.25 11.8 19.9 7.1 7.2 7.8 4.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 KFQ96096.1 - 0.29 11.4 16.4 2.3 8.5 4.3 4.1 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Rab5-bind PF09311.11 KFQ96096.1 - 0.42 9.9 17.6 0.047 13.1 6.2 3.0 1 1 1 2 2 2 0 Rabaptin-like protein DUF5595 PF18077.1 KFQ96096.1 - 0.47 10.6 4.5 13 6.0 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF5595) DUF2304 PF10066.9 KFQ96096.1 - 0.52 10.6 2.5 0.66 10.2 0.0 2.4 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2304) DUF1664 PF07889.12 KFQ96096.1 - 0.76 9.8 18.2 1.2 9.1 2.3 4.1 1 1 5 6 6 6 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KFQ96096.1 - 1.1 8.1 24.1 0.12 11.3 1.8 3.5 2 1 2 4 4 4 0 Spc7 kinetochore protein DivIC PF04977.15 KFQ96096.1 - 5.8 6.7 16.1 14 5.5 0.1 5.2 5 1 1 6 6 6 0 Septum formation initiator WD40 PF00400.32 KFQ96097.1 - 5.1e-63 207.5 37.3 4.9e-09 36.7 0.5 13.3 13 0 0 13 13 13 10 WD domain, G-beta repeat NB-ARC PF00931.22 KFQ96097.1 - 2.4e-57 194.0 1.3 2.8e-57 193.8 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain APAF1_C PF17908.1 KFQ96097.1 - 1.9e-54 183.3 1.8 5.4e-54 181.9 1.8 1.9 1 0 0 1 1 1 1 APAF-1 helical domain ANAPC4_WD40 PF12894.7 KFQ96097.1 - 1.4e-25 89.4 11.3 0.00042 20.6 0.1 9.7 2 2 9 11 11 11 8 Anaphase-promoting complex subunit 4 WD40 domain CARD PF00619.21 KFQ96097.1 - 3.4e-17 62.3 1.1 9.4e-17 60.8 1.1 1.9 1 0 0 1 1 1 1 Caspase recruitment domain Ge1_WD40 PF16529.5 KFQ96097.1 - 2.1e-11 43.3 7.6 0.0019 17.3 2.9 7.2 2 2 5 8 8 8 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFQ96097.1 - 6.2e-11 42.5 8.5 0.00019 21.4 0.1 5.1 3 2 2 5 5 5 2 Eukaryotic translation initiation factor eIF2A CARD_2 PF16739.5 KFQ96097.1 - 7.4e-10 38.7 0.4 2.2e-09 37.2 0.4 1.8 1 0 0 1 1 1 1 Caspase recruitment domain WD40_like PF17005.5 KFQ96097.1 - 3.8e-08 33.0 4.7 0.075 12.3 0.0 6.1 4 2 1 5 5 5 2 WD40-like domain AAA_16 PF13191.6 KFQ96097.1 - 0.00083 19.8 0.0 0.0017 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF2415 PF10313.9 KFQ96097.1 - 0.014 15.3 0.1 0.25 11.3 0.0 3.4 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) AAA_22 PF13401.6 KFQ96097.1 - 0.017 15.4 0.0 0.17 12.1 0.0 2.6 3 0 0 3 3 2 0 AAA domain DUF2856 PF11043.8 KFQ96097.1 - 0.16 12.1 0.9 8.6 6.6 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2856) PID PF00640.23 KFQ96098.1 - 9.3e-21 74.3 0.4 1.4e-20 73.8 0.4 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFQ96098.1 - 7.6e-06 26.1 0.1 1.1e-05 25.6 0.1 1.2 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.6 KFQ96098.1 - 4.2e-05 23.5 0.0 5.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Coq4 PF05019.13 KFQ96098.1 - 8.2e-05 22.0 0.1 0.00035 20.0 0.1 1.8 1 1 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Ank_2 PF12796.7 KFQ96099.1 - 2.8e-37 127.2 4.9 3.2e-12 46.8 0.1 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFQ96099.1 - 1.2e-36 124.3 8.6 1.2e-07 31.9 0.2 6.5 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFQ96099.1 - 2.9e-32 110.6 4.4 3.1e-08 34.0 0.1 4.9 4 1 0 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KFQ96099.1 - 8.9e-31 105.0 9.6 8.5e-05 22.8 0.1 7.2 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 KFQ96099.1 - 2.1e-30 101.3 2.1 5.3e-05 23.3 0.0 6.9 6 0 0 6 6 6 5 Ankyrin repeat SAM_1 PF00536.30 KFQ96099.1 - 5e-26 90.9 0.0 2.9e-15 56.4 0.0 2.8 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFQ96099.1 - 2.8e-22 78.6 0.3 1e-14 54.4 0.1 2.7 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) Chorein_N PF12624.7 KFQ96100.1 - 9.7e-17 61.2 1.4 2.6e-15 56.6 0.0 3.7 4 0 0 4 4 4 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 KFQ96100.1 - 0.0091 15.8 5.5 0.018 14.8 2.0 2.8 2 1 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal Actin PF00022.19 KFQ96101.1 - 3.4e-78 263.1 0.0 5.2e-77 259.1 0.0 1.9 1 1 0 1 1 1 1 Actin EcoRII-C PF09019.11 KFQ96101.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 EcoRII C terminal DEP PF00610.21 KFQ96102.1 - 1.1e-18 67.1 1.1 3.9e-18 65.3 0.2 2.5 3 0 0 3 3 3 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF2185 PF09951.9 KFQ96102.1 - 0.13 12.1 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2185) DUF1539 PF07560.11 KFQ96102.1 - 0.44 10.6 3.5 7.5 6.6 0.3 3.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) Pkinase PF00069.25 KFQ96103.1 - 1.8e-26 93.1 0.0 3.6e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ96103.1 - 3.5e-15 56.0 0.0 1.6e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase XRN_M PF17846.1 KFQ96103.1 - 0.018 14.0 1.4 0.036 13.0 1.4 1.4 1 0 0 1 1 1 0 Xrn1 helical domain MFS_1 PF07690.16 KFQ96104.1 - 6.1e-48 163.5 29.7 1.2e-46 159.3 28.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 KFQ96104.1 - 0.54 8.4 8.5 2.2 6.4 2.7 2.9 2 1 0 3 3 3 0 BT1 family zf-C4 PF00105.18 KFQ96105.1 - 1.4e-28 99.1 14.9 1.4e-28 99.1 14.9 1.7 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFQ96105.1 - 6.7e-26 91.1 0.8 6.7e-26 91.1 0.8 2.4 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor GAS2 PF02187.17 KFQ96106.1 - 2.8e-27 94.6 0.0 6.1e-27 93.5 0.0 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.31 KFQ96106.1 - 9.6e-11 41.8 0.0 1.5e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Anoctamin PF04547.12 KFQ96107.1 - 2.5e-162 540.8 13.0 3.1e-162 540.5 13.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KFQ96107.1 - 3.8e-75 252.5 2.2 7e-75 251.6 2.2 1.5 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Arf PF00025.21 KFQ96108.1 - 1.3e-75 252.7 0.1 1.5e-75 252.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFQ96108.1 - 3.8e-15 56.2 0.1 5e-15 55.8 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFQ96108.1 - 1.9e-13 50.3 0.0 2.2e-13 50.1 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFQ96108.1 - 1.8e-11 43.8 0.0 2.1e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFQ96108.1 - 3.1e-11 43.1 0.6 3.5e-07 29.7 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KFQ96108.1 - 3.1e-10 39.8 0.0 3.9e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFQ96108.1 - 1.4e-05 25.1 0.0 2.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 KFQ96108.1 - 0.0014 17.7 0.4 0.048 12.6 0.0 2.4 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 KFQ96108.1 - 0.0063 16.1 0.3 0.05 13.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KFQ96108.1 - 0.017 15.6 0.3 0.096 13.2 0.3 1.9 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KFQ96108.1 - 0.019 15.5 0.0 0.025 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KFQ96108.1 - 0.021 14.4 0.8 0.13 11.7 0.8 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B cobW PF02492.19 KFQ96108.1 - 0.085 12.4 0.3 8.3 6.0 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KFQ96108.1 - 0.085 12.8 0.1 13 5.7 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 KFQ96108.1 - 0.14 11.9 0.3 4 7.2 0.1 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KFQ96108.1 - 0.2 12.0 0.1 3.6 7.9 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain Nup192 PF11894.8 KFQ96109.1 - 0 1349.7 10.9 0 1349.4 10.9 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 zf-RING_4 PF14570.6 KFQ96111.1 - 3.5e-20 71.5 12.2 6.2e-20 70.7 12.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KFQ96111.1 - 1.7e-06 27.8 7.4 3.3e-06 26.8 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KFQ96111.1 - 8.4e-06 25.5 0.0 1.9e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 KFQ96111.1 - 0.0035 17.7 11.0 0.0077 16.5 11.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFQ96111.1 - 0.028 14.3 10.4 0.062 13.2 10.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ96111.1 - 0.035 14.0 9.9 0.075 12.9 9.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 KFQ96111.1 - 0.053 13.6 3.6 0.14 12.3 3.6 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_5 PF14634.6 KFQ96111.1 - 0.43 10.6 8.9 0.84 9.7 8.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KFQ96111.1 - 1.8 8.5 9.7 48 3.9 9.9 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Xan_ur_permease PF00860.20 KFQ96112.1 - 2e-89 300.0 25.6 2.7e-89 299.6 25.6 1.1 1 0 0 1 1 1 1 Permease family TadZ_N PF16968.5 KFQ96112.1 - 0.098 12.4 0.2 0.22 11.2 0.2 1.5 1 0 0 1 1 1 0 Pilus assembly protein TadZ N-terminal WD40 PF00400.32 KFQ96113.1 - 2.5e-11 43.9 10.1 0.0033 18.2 0.0 6.5 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ96113.1 - 8.7e-09 35.6 0.0 0.00021 21.5 0.0 3.0 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFQ96113.1 - 7.4e-05 21.9 0.2 0.00039 19.5 0.0 2.1 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4313 PF14190.6 KFQ96113.1 - 0.091 12.8 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4313) Ank_2 PF12796.7 KFQ96114.1 - 1.9e-28 98.9 4.1 7.6e-15 55.3 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFQ96114.1 - 3.7e-28 96.7 7.4 2.4e-06 27.7 0.0 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KFQ96114.1 - 4.9e-26 90.5 12.5 9.3e-09 35.4 1.1 3.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFQ96114.1 - 5.2e-26 90.7 6.7 2.9e-10 40.4 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ96114.1 - 2.5e-24 82.7 3.1 1.4e-06 28.1 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat CCDC84 PF14968.6 KFQ96114.1 - 0.02 14.5 1.2 3.5 7.2 0.0 2.8 1 1 2 3 3 3 0 Coiled coil protein 84 Mic1 PF07035.12 KFQ96114.1 - 0.039 13.6 0.5 0.17 11.6 0.1 2.0 2 1 0 2 2 2 0 Colon cancer-associated protein Mic1-like TM140 PF14985.6 KFQ96115.1 - 8e-24 84.2 1.0 9.2e-24 84.0 1.0 1.0 1 0 0 1 1 1 1 TM140 protein family Pepdidase_M14_N PF18027.1 KFQ96116.1 - 1e-21 77.3 2.5 2.3e-21 76.2 2.5 1.6 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 KFQ96116.1 - 3.5e-18 66.4 0.0 9.1e-18 65.1 0.0 1.7 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 KFQ96116.1 - 0.0018 17.4 0.0 0.0028 16.8 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family PDE6_gamma PF04868.12 KFQ96117.1 - 6.1e-47 157.8 0.9 6.7e-47 157.7 0.9 1.0 1 0 0 1 1 1 1 Retinal cGMP phosphodiesterase, gamma subunit Rho_GDI PF02115.17 KFQ96118.1 - 5.5e-76 254.7 0.2 6.4e-76 254.5 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Thioredoxin_6 PF13848.6 KFQ96119.1 - 3.1e-22 79.4 0.2 3.3e-22 79.3 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin-like domain ART PF01129.18 KFQ96122.1 - 1.1e-50 172.1 2.1 1.2e-50 171.9 2.1 1.0 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase ADPrib_exo_Tox PF03496.14 KFQ96122.1 - 0.00085 18.7 0.0 0.0016 17.8 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosyltransferase exoenzyme DUF4533 PF15047.6 KFQ96123.1 - 2e-28 99.5 0.4 2.3e-28 99.3 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4533) DUF4533 PF15047.6 KFQ96124.1 - 1.3e-65 221.2 8.0 7.2e-64 215.5 8.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4533) DNA_repr_REX1B PF14966.6 KFQ96124.1 - 0.046 14.4 3.8 0.15 12.7 0.6 2.4 2 1 1 3 3 3 0 DNA repair REX1-B Rit1_C PF17184.4 KFQ96124.1 - 0.078 12.4 0.5 0.34 10.3 0.1 1.9 2 0 0 2 2 2 0 Rit1 N-terminal domain SLATT_1 PF18181.1 KFQ96124.1 - 0.098 12.6 2.5 1.3 8.9 0.0 2.4 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 PI3K_P85_iSH2 PF16454.5 KFQ96124.1 - 0.11 12.1 4.8 0.25 11.0 1.7 2.2 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF2408 PF10303.9 KFQ96124.1 - 0.16 12.5 3.9 0.41 11.2 0.9 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) Wbp11 PF09429.10 KFQ96125.1 - 1.6e-22 79.7 13.8 1.6e-22 79.7 13.8 2.0 2 0 0 2 2 2 1 WW domain binding protein 11 MHB PF16525.5 KFQ96125.1 - 0.17 12.1 0.5 2.7 8.3 0.1 2.4 1 1 1 2 2 2 0 Haemophore, haem-binding TEX12 PF15219.6 KFQ96125.1 - 0.71 10.2 2.8 4.1 7.8 0.1 2.3 1 1 1 2 2 2 0 Testis-expressed 12 Histone_H2A_C PF16211.5 KFQ96126.1 - 1.7e-20 72.5 1.1 2.4e-20 71.9 1.1 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFQ96126.1 - 2e-07 31.4 0.0 2.6e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone PF00125.24 KFQ96127.1 - 1.3e-25 90.3 0.3 1.5e-25 90.0 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFQ96127.1 - 2.7e-06 27.6 0.5 6.2e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KFQ96127.1 - 0.0031 18.0 0.0 0.0059 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KFQ96127.1 - 0.057 13.1 0.4 1.7 8.2 0.0 2.0 1 1 1 2 2 2 0 Replication protein C N-terminal domain DUF5393 PF17371.2 KFQ96127.1 - 0.082 11.0 0.0 0.1 10.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5393) DUF2514 PF10721.9 KFQ96127.1 - 0.085 12.9 0.1 0.2 11.7 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) Histone_H2A_C PF16211.5 KFQ96128.1 - 4.2e-20 71.2 1.1 6.7e-20 70.5 1.1 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFQ96128.1 - 9.7e-12 45.4 0.0 1.2e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Ribosomal_L27A PF00828.19 KFQ96128.1 - 0.053 14.2 0.0 0.067 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Histone PF00125.24 KFQ96129.1 - 3.6e-26 92.1 0.5 4.4e-26 91.8 0.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFQ96129.1 - 1.3e-07 31.8 1.7 1.3e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 KFQ96129.1 - 0.00022 21.3 0.2 0.00027 21.0 0.2 1.1 1 0 0 1 1 1 1 YscO-like protein TFIID_20kDa PF03847.13 KFQ96129.1 - 0.0097 16.4 0.0 0.015 15.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.24 KFQ96130.1 - 8.4e-27 94.1 0.5 1e-26 93.8 0.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFQ96130.1 - 7.3e-07 29.4 1.6 8e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 KFQ96130.1 - 0.0019 18.2 0.3 0.0023 18.0 0.3 1.2 1 0 0 1 1 1 1 YscO-like protein TFIID_20kDa PF03847.13 KFQ96130.1 - 0.0024 18.3 0.0 0.0042 17.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A PXT1 PF15214.6 KFQ96131.1 - 0.13 12.6 0.4 0.31 11.4 0.1 1.8 2 0 0 2 2 2 0 Peroxisomal testis-specific protein 1 CENP-T_C PF15511.6 KFQ96132.1 - 1.8e-08 34.5 0.1 2.2e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KFQ96132.1 - 2.5e-05 24.4 0.2 3.5e-05 23.9 0.2 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KFQ96132.1 - 4.6e-05 23.7 0.1 6.1e-05 23.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 KFQ96132.1 - 0.00017 21.9 0.3 0.00019 21.8 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFQ96132.1 - 0.00028 21.1 0.1 0.00046 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFQ96132.1 - 0.0059 16.7 0.0 0.0067 16.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KFQ96132.1 - 0.024 14.6 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KFQ96132.1 - 0.21 11.4 0.1 0.25 11.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone_H2A_C PF16211.5 KFQ96133.1 - 1.6e-20 72.5 1.8 2.3e-20 72.0 1.8 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFQ96133.1 - 4.7e-11 43.2 0.0 6.3e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone PF00125.24 KFQ96134.1 - 6.8e-26 91.2 0.2 8.4e-26 90.9 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFQ96134.1 - 8.9e-07 29.1 0.7 1.8e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KFQ96134.1 - 0.0031 18.0 0.0 0.006 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KFQ96134.1 - 0.0034 17.4 0.3 0.0039 17.2 0.3 1.2 1 0 0 1 1 1 1 YscO-like protein Linker_histone PF00538.19 KFQ96135.1 - 4e-21 75.2 0.5 4e-21 75.2 0.5 1.8 2 0 0 2 2 2 1 linker histone H1 and H5 family CENP-T_C PF15511.6 KFQ96136.1 - 1.8e-08 34.5 0.1 2.2e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KFQ96136.1 - 2.5e-05 24.4 0.2 3.5e-05 23.9 0.2 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KFQ96136.1 - 4.6e-05 23.7 0.1 6.1e-05 23.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 KFQ96136.1 - 0.00017 21.9 0.3 0.00019 21.8 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFQ96136.1 - 0.00028 21.1 0.1 0.00046 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFQ96136.1 - 0.0059 16.7 0.0 0.0067 16.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KFQ96136.1 - 0.024 14.6 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KFQ96136.1 - 0.21 11.4 0.1 0.25 11.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) PXT1 PF15214.6 KFQ96137.1 - 0.13 12.6 0.4 0.31 11.4 0.1 1.8 2 0 0 2 2 2 0 Peroxisomal testis-specific protein 1 Histone PF00125.24 KFQ96138.1 - 2.7e-53 179.8 1.7 3e-53 179.7 1.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KFQ96138.1 - 8.6e-05 22.6 0.3 0.00015 21.8 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KFQ96138.1 - 0.00043 20.6 0.0 0.00064 20.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 KFQ96138.1 - 0.0015 19.1 2.2 0.0019 18.8 2.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KFQ96138.1 - 0.011 16.0 0.1 0.022 15.0 0.1 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFQ96138.1 - 0.12 12.5 0.2 0.22 11.6 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CDC37_M PF08565.11 KFQ96139.1 - 7.9e-20 71.0 0.1 1.5e-19 70.0 0.1 1.4 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain ADK PF00406.22 KFQ96140.1 - 4.9e-31 107.9 0.0 5.7e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.14 KFQ96140.1 - 2.5e-17 62.6 0.0 8.2e-17 60.9 0.0 1.9 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_17 PF13207.6 KFQ96140.1 - 8.8e-05 22.9 0.0 0.00018 21.9 0.0 1.5 2 0 0 2 2 2 1 AAA domain Sad1_UNC PF07738.13 KFQ96141.1 - 1.7e-37 128.4 0.0 1.8e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal SDF PF00375.18 KFQ96142.1 - 4.2e-123 411.2 27.6 4.8e-123 411.0 27.6 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Xlink PF00193.17 KFQ96143.1 - 1.9e-20 73.1 0.5 4.6e-20 71.8 0.0 1.9 2 0 0 2 2 2 1 Extracellular link domain LYRIC PF15686.5 KFQ96143.1 - 0.036 13.6 0.8 0.047 13.3 0.3 1.4 1 1 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family MAP17 PF15807.5 KFQ96143.1 - 0.19 12.0 0.3 0.36 11.0 0.3 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 2-oxoacid_dh PF00198.23 KFQ96144.1 - 1.3e-75 253.9 0.2 1.8e-75 253.4 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFQ96144.1 - 1.4e-20 72.8 0.4 3.3e-20 71.7 0.4 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KFQ96144.1 - 1.2e-10 41.5 0.0 3.5e-10 40.0 0.0 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KFQ96144.1 - 0.00018 21.2 0.0 0.014 15.2 0.0 2.8 2 1 1 3 3 3 1 Biotin-lipoyl like QRPTase_N PF02749.16 KFQ96144.1 - 0.15 12.1 0.0 0.46 10.6 0.0 1.8 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain CIDE-N PF02017.15 KFQ96144.1 - 0.23 11.5 0.6 0.6 10.2 0.1 1.9 2 0 0 2 2 2 0 CIDE-N domain Aldolase_II PF00596.21 KFQ96145.1 - 2.8e-46 157.8 0.0 3.3e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Syja_N PF02383.18 KFQ96145.1 - 0.18 11.0 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 SacI homology domain Ets PF00178.22 KFQ96146.1 - 9.6e-34 115.7 3.8 3.5e-33 113.9 0.6 2.5 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.16 KFQ96146.1 - 7.1e-25 86.8 3.5 8e-25 86.6 2.4 1.8 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain Acetyltransf_2 PF00797.17 KFQ96146.1 - 0.016 15.0 0.2 0.081 12.7 0.2 2.1 1 1 0 1 1 1 0 N-acetyltransferase Ras PF00071.22 KFQ96147.1 - 8.2e-51 171.8 0.0 8.2e-51 171.8 0.0 1.8 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KFQ96147.1 - 1.4e-30 106.0 0.0 3.4e-30 104.7 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ96147.1 - 5.5e-17 61.8 0.0 1.5e-16 60.3 0.0 1.8 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFQ96147.1 - 2.3e-08 34.1 0.0 7.9e-08 32.4 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFQ96147.1 - 0.00056 19.5 0.1 0.00056 19.5 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFQ96147.1 - 0.063 12.6 5.9 0.066 12.6 0.0 3.0 2 1 1 3 3 3 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KFQ96147.1 - 0.25 11.3 5.4 4.2 7.2 0.0 3.3 3 1 1 4 4 4 0 RsgA GTPase AAA_25 PF13481.6 KFQ96147.1 - 0.4 10.2 1.8 2 7.9 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KFQ96147.1 - 0.62 10.2 0.0 0.62 10.2 0.0 3.5 4 1 0 4 4 4 0 AAA domain DUF2514 PF10721.9 KFQ96147.1 - 1 9.4 7.7 2.9 7.9 7.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) GIT_CC PF16559.5 KFQ96147.1 - 1.9 8.4 14.0 8.8 6.3 0.1 4.0 2 1 2 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor TTKRSYEDQ PF10212.9 KFQ96147.1 - 2.7 6.9 23.0 0.56 9.1 19.3 1.7 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein NitrOD5 PF11537.8 KFQ96147.1 - 6.8 6.9 8.4 5 7.3 4.0 2.8 3 0 0 3 3 3 0 Nitrosopumilus output domain 5 Z1 PF10593.9 KFQ96147.1 - 7.5 6.0 12.7 6 6.3 10.0 2.0 1 1 1 2 2 2 0 Z1 domain FUSC-like PF12805.7 KFQ96147.1 - 8.7 5.3 10.5 0.19 10.8 3.4 1.8 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS FERM_M PF00373.18 KFQ96148.1 - 8.9e-19 68.0 0.2 2.2e-18 66.8 0.0 1.8 2 0 0 2 2 2 1 FERM central domain FERM_C PF09380.10 KFQ96148.1 - 5.3e-17 62.0 0.4 1.1e-16 61.0 0.4 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FA PF08736.11 KFQ96148.1 - 2.2e-13 50.0 1.4 4.5e-13 49.0 1.4 1.5 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_N PF09379.10 KFQ96148.1 - 1.3e-11 44.2 0.0 2.4e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 FERM N-terminal domain SKI PF01202.22 KFQ96149.1 - 0.00013 22.1 0.0 0.00044 20.4 0.0 1.8 1 1 0 1 1 1 1 Shikimate kinase ubiquitin PF00240.23 KFQ96150.1 - 4.9e-13 48.6 0.4 9e-13 47.8 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin family STI1 PF17830.1 KFQ96150.1 - 5.2e-10 39.1 61.3 0.00013 21.9 10.2 6.6 3 2 3 6 6 6 5 STI1 domain UBA PF00627.31 KFQ96150.1 - 6.1e-08 32.4 0.6 1.9e-07 30.8 0.6 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 KFQ96150.1 - 0.0021 17.9 0.1 0.0042 16.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RasGAP PF00616.19 KFQ96150.1 - 0.0033 17.2 1.4 0.02 14.6 0.0 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase Rad60-SLD_2 PF13881.6 KFQ96150.1 - 0.015 15.4 0.2 0.029 14.5 0.2 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like HOIP-UBA PF16678.5 KFQ96150.1 - 0.031 14.3 0.2 0.087 12.8 0.0 1.8 2 0 0 2 2 2 0 HOIP UBA domain pair CUE PF02845.16 KFQ96150.1 - 0.068 12.9 1.5 0.23 11.2 0.0 2.6 2 0 0 2 2 2 0 CUE domain DUF2407 PF10302.9 KFQ96150.1 - 0.15 12.6 0.1 0.67 10.6 0.1 2.1 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Clathrin-link PF09268.10 KFQ96150.1 - 1.8 8.0 15.9 6.5 6.2 0.1 5.2 5 0 0 5 5 5 0 Clathrin, heavy-chain linker TetR_C_13 PF16925.5 KFQ96151.1 - 7 6.6 7.8 1.8 8.5 1.2 2.7 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Kinesin PF00225.23 KFQ96152.1 - 7.3e-110 367.0 1.5 7.3e-110 367.0 1.5 3.3 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KFQ96152.1 - 4.5e-24 85.1 0.0 4.5e-24 85.1 0.0 3.2 3 0 0 3 3 3 1 Microtubule binding Q_salvage PF10343.9 KFQ96153.1 - 7.9e-92 307.8 0.1 8.8e-92 307.7 0.1 1.0 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family RMI1_N PF08585.12 KFQ96154.1 - 3.4e-55 187.2 0.1 5.9e-55 186.4 0.1 1.4 1 0 0 1 1 1 1 RecQ mediated genome instability protein RMI1_C PF16099.5 KFQ96154.1 - 6.5e-46 155.7 0.0 1.9e-45 154.2 0.0 1.8 2 0 0 2 2 2 1 Recq-mediated genome instability protein 1, C-terminal OB-fold Nucleos_tra2_C PF07662.13 KFQ96155.1 - 7.6e-77 257.8 5.3 7.6e-77 257.8 5.3 2.5 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KFQ96155.1 - 1.6e-22 79.9 3.5 1.6e-22 79.9 3.5 4.3 4 1 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 KFQ96155.1 - 2.8e-06 27.6 9.3 2.8e-06 27.6 9.3 4.1 4 0 0 4 4 4 1 Nucleoside recognition Yae1_N PF09811.9 KFQ96156.1 - 6.7e-11 41.7 41.5 0.016 14.9 4.3 4.3 2 1 0 2 2 2 2 Essential protein Yae1, N terminal Pepdidase_M14_N PF18027.1 KFQ96157.1 - 1.1e-15 57.9 1.7 2.9e-15 56.6 1.7 1.7 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 KFQ96157.1 - 8.4e-13 48.8 0.0 2e-12 47.6 0.0 1.7 1 1 0 1 1 1 1 Zinc carboxypeptidase V-ATPase_H_N PF03224.14 KFQ96157.1 - 0.001 18.5 0.0 0.0067 15.8 0.0 2.1 1 1 0 1 1 1 1 V-ATPase subunit H AstE_AspA PF04952.14 KFQ96157.1 - 0.0074 15.4 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Mak10 PF04112.13 KFQ96158.1 - 5.2e-35 120.4 2.1 9.7e-26 90.3 0.1 2.9 2 1 1 3 3 3 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Rer1 PF03248.13 KFQ96158.1 - 0.0017 18.2 0.8 0.0034 17.1 0.8 1.5 1 0 0 1 1 1 1 Rer1 family CTP_transf_like PF01467.26 KFQ96159.1 - 0.89 9.7 3.9 1.2 9.3 0.6 2.2 2 0 0 2 2 2 0 Cytidylyltransferase-like Fe-S_biosyn PF01521.20 KFQ96160.1 - 8.4e-19 67.8 0.0 9.3e-19 67.7 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis TUTF7_u4 PF16631.5 KFQ96161.1 - 5.9e-38 129.4 20.8 5.9e-38 129.4 20.8 3.3 4 0 0 4 4 1 1 Unstructured region 4 on terminal uridylyltransferase 7 PAP_assoc PF03828.19 KFQ96161.1 - 4e-27 94.2 0.1 2.2e-14 53.4 0.2 3.1 2 0 0 2 2 2 2 Cid1 family poly A polymerase zf-CCHC PF00098.23 KFQ96161.1 - 9.5e-12 44.4 24.3 3.3e-05 23.7 2.3 4.1 4 0 0 4 4 4 3 Zinc knuckle NTP_transf_2 PF01909.23 KFQ96161.1 - 5.4e-06 26.6 0.0 6.9e-05 23.1 0.0 2.9 2 0 0 2 2 2 1 Nucleotidyltransferase domain zf-CCHC_2 PF13696.6 KFQ96161.1 - 0.00034 20.3 33.6 0.012 15.5 5.7 4.9 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_4 PF14392.6 KFQ96161.1 - 0.00051 19.7 13.1 0.23 11.2 0.3 3.7 3 0 0 3 3 3 3 Zinc knuckle tRNA_NucTransf2 PF09249.11 KFQ96161.1 - 0.00069 19.9 0.0 2.7 8.3 0.0 2.9 2 0 0 2 2 2 2 tRNA nucleotidyltransferase, second domain Polbeta PF18765.1 KFQ96161.1 - 0.0043 17.1 0.0 0.24 11.5 0.0 2.8 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase Spt46 PF17734.1 KFQ96161.1 - 0.014 15.2 0.4 0.45 10.3 0.1 2.6 2 0 0 2 2 2 0 Spermatogenesis-associated protein 46 zf-C2H2_jaz PF12171.8 KFQ96161.1 - 0.039 14.3 3.2 0.14 12.5 3.2 2.1 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFQ96161.1 - 0.091 13.1 5.4 0.081 13.3 0.8 3.0 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Pkinase PF00069.25 KFQ96163.1 - 2.1e-70 237.1 0.0 3e-70 236.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 KFQ96163.1 - 1.9e-52 175.8 3.6 5.1e-17 62.2 0.0 4.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ96163.1 - 8.5e-45 150.6 3.3 3.3e-09 37.1 0.0 7.2 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFQ96163.1 - 1.8e-44 149.2 11.0 1.9e-09 37.6 0.0 7.5 1 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 KFQ96163.1 - 2.9e-39 131.8 7.0 6.5e-06 26.4 0.0 9.1 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 KFQ96163.1 - 1.4e-36 120.4 8.5 9.5e-05 22.5 0.0 8.8 8 0 0 8 8 8 7 Ankyrin repeat Pkinase_Tyr PF07714.17 KFQ96163.1 - 5.8e-34 117.5 0.0 1.2e-33 116.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KFQ96163.1 - 6.1e-06 25.7 0.1 1.5e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFQ96163.1 - 0.00012 21.7 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Roc PF08477.13 KFQ96163.1 - 0.0048 17.1 0.1 2.5 8.3 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 KFQ96163.1 - 0.024 15.2 0.2 0.082 13.4 0.0 2.0 3 0 0 3 3 2 0 AAA domain Kinase-like PF14531.6 KFQ96163.1 - 0.024 14.0 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 KFQ96163.1 - 0.032 13.8 0.0 0.071 12.7 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 KFQ96163.1 - 0.049 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3847 PF12958.7 KFQ96163.1 - 0.069 13.3 0.2 0.28 11.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) ABC_tran PF00005.27 KFQ96163.1 - 0.072 13.6 0.1 0.27 11.8 0.1 1.9 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 KFQ96163.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Death PF00531.22 KFQ96164.1 - 8.6e-22 77.1 0.4 2.7e-20 72.3 0.0 3.2 3 1 0 3 3 3 1 Death domain COR PF16095.5 KFQ96164.1 - 2.5e-08 34.0 0.1 4.1e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Peptidase_C1 PF00112.23 KFQ96165.1 - 1.1e-88 297.0 2.6 1.6e-88 296.4 2.6 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KFQ96165.1 - 3.6e-12 46.5 1.6 7e-12 45.6 1.6 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KFQ96165.1 - 2.9e-06 26.3 2.8 0.00035 19.5 1.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Lipocalin_8 PF16585.5 KFQ96165.1 - 0.022 15.2 0.9 0.042 14.3 0.9 1.4 1 0 0 1 1 1 0 Lipocalin-like domain Styelin PF17562.2 KFQ96165.1 - 0.058 13.7 0.1 0.15 12.5 0.1 1.6 1 0 0 1 1 1 0 Styelin FBPase PF00316.20 KFQ96166.1 - 4.1e-73 244.9 0.1 5.5e-73 244.5 0.1 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 KFQ96166.1 - 0.00013 21.6 0.0 0.00026 20.6 0.0 1.5 2 0 0 2 2 2 1 Inositol monophosphatase family FBPase PF00316.20 KFQ96167.1 - 6.1e-79 263.9 0.3 8e-79 263.5 0.3 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 KFQ96167.1 - 9.3e-06 25.3 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Inositol monophosphatase family Peptidase_M1 PF01433.20 KFQ96168.1 - 8.9e-22 77.7 0.0 2.9e-21 76.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KFQ96168.1 - 7.5e-07 29.5 0.1 1.3e-05 25.4 0.0 2.6 2 1 1 3 3 3 1 Peptidase M1 N-terminal domain Fanconi_C PF02106.15 KFQ96169.1 - 8.5e-251 833.5 20.0 9.7e-251 833.4 20.0 1.0 1 0 0 1 1 1 1 Fanconi anaemia group C protein EF-hand_2 PF09068.11 KFQ96169.1 - 0.00097 19.3 0.0 0.82 9.8 0.0 2.8 2 1 0 2 2 2 2 EF hand Patched PF02460.18 KFQ96170.1 - 1.8e-64 218.2 13.8 5.1e-32 110.9 10.7 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 KFQ96170.1 - 3.2e-32 111.5 2.3 3.2e-32 111.5 2.3 2.4 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation 7tm_1 PF00001.21 KFQ96171.1 - 1.6e-34 119.4 7.8 2.3e-34 118.9 7.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFQ96171.1 - 1.3e-05 24.7 2.4 1.8e-05 24.3 2.4 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 KFQ96171.1 - 0.0045 16.6 5.7 0.0072 16.0 5.7 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx E1-E2_ATPase PF00122.20 KFQ96172.1 - 3.9e-13 49.3 1.3 3.6e-12 46.2 0.5 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 KFQ96172.1 - 4.7e-09 35.8 0.0 8.1e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus BCCT PF02028.17 KFQ96172.1 - 0.062 11.7 0.0 0.075 11.5 0.0 1.0 1 0 0 1 1 1 0 BCCT, betaine/carnitine/choline family transporter Keratin PF02422.16 KFQ96175.1 - 6e-35 118.8 13.5 6.5e-35 118.7 13.5 1.0 1 0 0 1 1 1 1 Keratin Homeodomain PF00046.29 KFQ96176.1 - 1.9e-20 72.4 4.8 3.4e-20 71.6 4.8 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ96176.1 - 0.078 12.9 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain Sds3 PF08598.11 KFQ96178.1 - 6.7e-25 88.4 8.6 3.1e-24 86.2 9.3 1.5 1 1 1 2 2 2 1 Sds3-like Borrelia_P83 PF05262.11 KFQ96178.1 - 0.22 10.0 5.7 0.31 9.5 5.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Ank PF00023.30 KFQ96180.1 - 3.8e-27 93.5 8.3 5.9e-07 29.6 0.2 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.7 KFQ96180.1 - 6.7e-27 93.9 4.5 8.2e-13 48.8 0.3 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFQ96180.1 - 2.2e-26 91.5 4.2 3.9e-10 39.8 0.0 3.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ96180.1 - 1.4e-23 80.4 4.2 7e-06 26.0 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KFQ96180.1 - 4.3e-21 75.0 1.6 4.5e-09 36.7 0.2 4.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) CRR7 PF12095.8 KFQ96180.1 - 0.034 14.6 0.3 0.16 12.4 0.0 2.2 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 Proteasome PF00227.26 KFQ96181.1 - 3e-53 180.2 0.2 3.4e-53 180.0 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit PRORP PF16953.5 KFQ96182.1 - 8.6e-95 316.8 2.9 1e-94 316.6 1.9 1.6 2 0 0 2 2 2 1 Protein-only RNase P PPR_2 PF13041.6 KFQ96182.1 - 1.1e-08 35.1 1.3 0.046 13.9 0.0 4.2 4 1 1 5 5 5 2 PPR repeat family PPR PF01535.20 KFQ96182.1 - 7.2e-06 25.9 9.8 0.0063 16.7 0.1 4.7 5 0 0 5 5 5 2 PPR repeat RNase_Zc3h12a PF11977.8 KFQ96182.1 - 0.0053 16.5 0.1 0.014 15.2 0.1 1.7 1 1 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PPR_long PF17177.4 KFQ96182.1 - 0.006 16.0 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP Rad50_zn_hook PF04423.14 KFQ96182.1 - 0.015 15.1 0.2 0.5 10.3 0.1 2.8 2 0 0 2 2 2 0 Rad50 zinc hook motif Baculo_VP39 PF04501.12 KFQ96182.1 - 0.04 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Baculovirus major capsid protein VP39 PPR_3 PF13812.6 KFQ96182.1 - 0.13 12.3 0.2 21 5.3 0.0 3.5 2 1 2 4 4 4 0 Pentatricopeptide repeat domain EF-hand_7 PF13499.6 KFQ96183.1 - 9.1e-09 35.6 7.6 2.7e-05 24.5 0.2 5.0 4 1 1 5 5 5 2 EF-hand domain pair EF-hand_6 PF13405.6 KFQ96183.1 - 2.2e-06 27.1 3.9 0.49 10.5 0.1 5.4 5 0 0 5 5 5 2 EF-hand domain EF-hand_13 PF17958.1 KFQ96183.1 - 7.7e-06 25.6 0.1 4.8e-05 23.1 0.0 2.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 KFQ96183.1 - 3.9e-05 22.9 0.6 0.26 10.9 0.0 4.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KFQ96183.1 - 0.01 15.6 0.0 1.8 8.5 0.0 3.0 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 KFQ96183.1 - 0.028 13.9 0.9 0.13 11.8 0.0 2.7 3 0 0 3 3 3 0 EF hand FAM177 PF14774.6 KFQ96184.1 - 4.4e-28 98.0 0.1 4.4e-28 98.0 0.1 1.9 1 1 1 2 2 2 1 FAM177 family DUF719 PF05334.13 KFQ96184.1 - 0.0003 21.1 0.1 0.00037 20.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF719) PAF PF15715.5 KFQ96184.1 - 0.0013 19.3 2.5 0.0015 19.2 2.5 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain Connexin PF00029.19 KFQ96184.1 - 0.0037 17.0 0.3 0.0041 16.9 0.3 1.2 1 0 0 1 1 1 1 Connexin ZapB PF06005.12 KFQ96184.1 - 0.016 15.7 7.1 0.023 15.1 7.1 1.2 1 0 0 1 1 1 0 Cell division protein ZapB CPSF100_C PF13299.6 KFQ96184.1 - 0.062 13.5 0.8 0.071 13.3 0.8 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SRP54 PF00448.22 KFQ96185.1 - 1.7e-77 259.5 0.4 7.3e-77 257.4 0.1 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KFQ96185.1 - 2.4e-30 105.1 2.7 2.4e-30 105.1 2.7 3.2 2 1 2 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 KFQ96185.1 - 1e-20 73.7 3.1 3.4e-20 72.1 3.1 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KFQ96185.1 - 3.4e-07 30.0 0.7 3.3e-06 26.8 0.5 2.4 2 1 0 2 2 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KFQ96185.1 - 6.4e-06 26.4 0.0 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KFQ96185.1 - 3e-05 24.1 0.0 0.00011 22.3 0.0 1.9 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2209 PF09974.9 KFQ96185.1 - 0.00016 22.0 0.3 0.00044 20.6 0.3 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2209) SRPRB PF09439.10 KFQ96185.1 - 0.00025 20.5 0.5 0.62 9.5 0.0 2.7 1 1 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KFQ96185.1 - 0.0007 19.9 0.5 0.0066 16.7 0.1 2.7 3 1 0 3 3 2 1 AAA domain MeaB PF03308.16 KFQ96185.1 - 0.0018 17.3 0.0 0.041 12.9 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KFQ96185.1 - 0.0043 16.8 0.0 0.015 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_31 PF13614.6 KFQ96185.1 - 0.0059 16.5 0.6 0.023 14.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFQ96185.1 - 0.0062 16.6 2.0 0.017 15.2 0.2 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.6 KFQ96185.1 - 0.0099 16.3 1.1 0.0099 16.3 1.1 3.0 3 1 0 3 3 1 1 AAA domain ResIII PF04851.15 KFQ96185.1 - 0.01 15.9 0.5 0.028 14.4 0.5 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit GTP_EFTU PF00009.27 KFQ96185.1 - 0.011 15.2 0.4 0.095 12.2 0.4 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFQ96185.1 - 0.015 15.7 0.0 0.039 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain CLP1_P PF16575.5 KFQ96185.1 - 0.022 14.6 0.6 0.84 9.4 0.1 2.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ATP_bind_1 PF03029.17 KFQ96185.1 - 0.024 14.4 1.3 0.18 11.5 0.1 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.14 KFQ96185.1 - 0.027 14.4 0.4 0.1 12.5 0.0 2.2 2 1 1 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.20 KFQ96185.1 - 0.031 14.2 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 KFQ96185.1 - 0.033 14.7 0.1 0.11 13.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 KFQ96185.1 - 0.041 13.2 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_28 PF13521.6 KFQ96185.1 - 0.045 14.0 0.0 0.086 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KFQ96185.1 - 0.049 14.1 1.9 0.46 10.9 0.2 3.2 2 2 1 3 3 1 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 KFQ96185.1 - 0.05 12.8 0.4 0.33 10.1 0.3 2.5 1 1 0 1 1 1 0 G-protein alpha subunit AAA_15 PF13175.6 KFQ96185.1 - 0.065 12.9 0.3 0.5 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.9 KFQ96185.1 - 0.08 12.7 0.4 0.86 9.3 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation YlbD_coat PF14071.6 KFQ96185.1 - 6.9 6.9 11.6 14 6.0 3.2 4.5 2 1 2 4 4 4 0 Putative coat protein Methyltransf_11 PF08241.12 KFQ96186.1 - 2.8e-05 24.7 0.1 6.6e-05 23.5 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain CheR PF01739.18 KFQ96186.1 - 9.4e-05 22.0 0.1 0.00015 21.3 0.1 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_12 PF08242.12 KFQ96186.1 - 0.00012 22.8 0.0 0.00022 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFQ96186.1 - 0.00022 21.8 0.1 0.00051 20.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KFQ96186.1 - 0.006 16.4 0.1 0.01 15.6 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein DOT1 PF08123.13 KFQ96186.1 - 0.011 15.3 1.4 0.15 11.6 1.3 2.3 1 1 0 1 1 1 0 Histone methylation protein DOT1 NTP_transf_3 PF12804.7 KFQ96186.1 - 0.11 12.8 0.0 2.4 8.5 0.0 2.1 2 0 0 2 2 2 0 MobA-like NTP transferase domain YdfZ PF14001.6 KFQ96186.1 - 0.15 12.5 0.0 0.34 11.4 0.0 1.5 1 0 0 1 1 1 0 YdfZ protein WSD PF15613.6 KFQ96187.1 - 7.2e-30 103.4 0.0 7.2e-30 103.4 0.0 4.8 4 2 0 4 4 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WAC_Acf1_DNA_bd PF10537.9 KFQ96187.1 - 9e-25 87.1 0.0 9e-25 87.1 0.0 4.2 4 1 0 4 4 3 1 ATP-utilising chromatin assembly and remodelling N-terminal Bromodomain PF00439.25 KFQ96187.1 - 2.1e-20 72.6 0.4 4.3e-20 71.6 0.4 1.6 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 KFQ96187.1 - 4e-14 52.2 5.8 9.1e-14 51.1 5.8 1.7 1 0 0 1 1 1 1 PHD-finger DDT PF02791.17 KFQ96187.1 - 1.1e-09 38.5 2.4 1.1e-09 38.5 2.4 2.8 3 0 0 3 3 2 1 DDT domain WHIM1 PF15612.6 KFQ96187.1 - 3.2e-09 36.1 0.0 9.9e-09 34.5 0.0 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Prok-RING_1 PF14446.6 KFQ96187.1 - 0.06 13.3 2.4 0.17 11.8 2.4 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.6 KFQ96187.1 - 0.063 13.5 1.7 0.31 11.3 1.7 2.2 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-rbx1 PF12678.7 KFQ96187.1 - 0.1 12.9 3.0 0.27 11.5 3.0 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain Zf_RING PF16744.5 KFQ96187.1 - 0.12 12.5 2.0 0.41 10.8 2.0 2.0 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_2 PF13639.6 KFQ96187.1 - 0.47 10.8 5.4 0.95 9.8 5.4 1.6 1 0 0 1 1 1 0 Ring finger domain Cofilin_ADF PF00241.20 KFQ96188.1 - 2.3e-33 114.5 0.9 3.1e-33 114.1 0.9 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PX PF00787.24 KFQ96189.1 - 7.7e-20 71.0 1.1 1.7e-15 57.0 1.2 3.3 2 1 0 2 2 2 1 PX domain Vps5 PF09325.10 KFQ96189.1 - 8.2e-16 58.3 15.2 7.9e-14 51.8 12.4 2.7 2 1 0 2 2 2 1 Vps5 C terminal like BAR PF03114.18 KFQ96189.1 - 1.6e-05 24.7 15.7 0.0011 18.6 10.6 2.7 3 1 0 3 3 3 2 BAR domain Eapp_C PF10238.9 KFQ96190.1 - 1.8e-52 177.4 8.7 1.8e-52 177.4 8.7 1.8 2 1 0 2 2 2 1 E2F-associated phosphoprotein C1_4 PF07975.12 KFQ96190.1 - 0.025 14.8 2.4 0.059 13.6 0.3 2.4 2 0 0 2 2 2 0 TFIIH C1-like domain DUF5470 PF17564.2 KFQ96190.1 - 0.028 14.6 0.3 0.074 13.2 0.2 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5470) Fer4_22 PF17179.4 KFQ96190.1 - 2.3 9.1 8.6 3.1 8.7 7.0 1.9 2 0 0 2 2 2 0 4Fe-4S dicluster domain Yippee-Mis18 PF03226.14 KFQ96190.1 - 3.1 8.1 7.7 12 6.2 7.7 1.9 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SPT_ssu-like PF11779.8 KFQ96191.1 - 1.7e-05 24.3 0.2 2.1e-05 24.1 0.2 1.1 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like COX14 PF14880.6 KFQ96191.1 - 0.081 12.8 1.1 0.087 12.7 1.1 1.0 1 0 0 1 1 1 0 Cytochrome oxidase c assembly 2OG-FeII_Oxy_3 PF13640.6 KFQ96192.1 - 1.9e-15 57.5 0.0 2.1e-15 57.4 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KFQ96192.1 - 7.5e-09 36.1 0.0 7.7e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PAS_3 PF08447.12 KFQ96193.1 - 2.4e-24 85.4 0.2 1e-18 67.4 0.2 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KFQ96193.1 - 7.9e-13 48.5 0.0 4e-09 36.6 0.1 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 KFQ96193.1 - 5.3e-11 42.5 0.0 1.7e-07 31.2 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KFQ96193.1 - 2.9e-08 33.9 0.0 0.00013 22.2 0.1 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KFQ96193.1 - 0.00043 20.5 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 KFQ96194.1 - 2.5e-05 24.2 0.6 3.2e-05 23.8 0.6 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RhoGAP PF00620.27 KFQ96197.1 - 1e-47 161.7 0.9 1.9e-47 160.9 0.1 1.9 2 0 0 2 2 2 1 RhoGAP domain RhoGAP-FF1 PF16512.5 KFQ96197.1 - 5.6e-30 103.9 14.1 2.4e-28 98.6 6.7 4.3 4 0 0 4 4 4 1 p190-A and -B Rho GAPs FF domain FF PF01846.19 KFQ96197.1 - 5e-14 52.2 10.0 7.5e-10 38.8 1.3 4.5 4 0 0 4 4 4 3 FF domain Ras PF00071.22 KFQ96197.1 - 8.5e-14 51.5 3.9 4.9e-05 23.0 0.3 4.5 4 0 0 4 4 4 4 Ras family AAA_22 PF13401.6 KFQ96197.1 - 0.0037 17.5 0.1 2.1 8.6 0.1 3.0 2 0 0 2 2 2 1 AAA domain NOG1 PF06858.14 KFQ96197.1 - 0.0062 16.3 0.1 0.02 14.7 0.1 1.9 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) GTP_EFTU PF00009.27 KFQ96197.1 - 0.0084 15.7 0.2 0.031 13.8 0.2 2.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Roc PF08477.13 KFQ96197.1 - 0.014 15.6 0.1 0.63 10.3 0.0 3.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KFQ96197.1 - 0.068 13.3 0.0 0.48 10.5 0.0 2.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase U5_2-snRNA_bdg PF10597.9 KFQ96197.1 - 0.096 12.8 0.9 0.31 11.1 0.2 2.1 2 0 0 2 2 2 0 U5-snRNA binding site 2 of PrP8 ParA PF10609.9 KFQ96198.1 - 1.4e-97 326.0 1.1 1.6e-97 325.8 1.1 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KFQ96198.1 - 2.7e-11 43.6 0.0 6.6e-11 42.4 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KFQ96198.1 - 1.9e-08 34.4 0.1 2.3e-06 27.7 0.1 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 KFQ96198.1 - 7.2e-07 28.8 0.0 1.2e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 KFQ96198.1 - 2.1e-05 23.9 0.5 0.00071 18.8 0.3 2.6 2 1 1 3 3 3 1 Anion-transporting ATPase Fer4_NifH PF00142.18 KFQ96198.1 - 0.00066 19.2 0.8 0.0031 17.0 0.8 2.1 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 KFQ96198.1 - 0.0014 18.3 0.4 0.0033 17.0 0.1 1.7 2 0 0 2 2 2 1 AAA domain VirC1 PF07015.11 KFQ96198.1 - 0.015 14.6 0.0 0.032 13.5 0.0 1.5 2 0 0 2 2 2 0 VirC1 protein AAA_26 PF13500.6 KFQ96198.1 - 0.12 12.1 0.5 0.89 9.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain Tyr_Deacylase PF02580.16 KFQ96199.1 - 4.3e-30 105.1 0.0 4.8e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase HEAT_2 PF13646.6 KFQ96200.1 - 1.1e-09 38.6 14.5 1.2 9.6 0.1 8.9 7 1 2 9 9 9 5 HEAT repeats HEAT PF02985.22 KFQ96200.1 - 1.4e-09 37.4 33.6 0.017 15.3 0.7 11.0 11 0 0 11 11 11 3 HEAT repeat Vac14_Fab1_bd PF12755.7 KFQ96200.1 - 0.00044 20.8 0.0 0.0099 16.5 0.0 3.4 2 1 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KFQ96200.1 - 0.013 15.9 30.9 0.32 11.5 0.4 9.5 10 0 0 10 10 10 0 HEAT-like repeat OSCP PF00213.18 KFQ96200.1 - 0.042 14.0 0.0 0.15 12.2 0.0 2.0 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit Cnd1 PF12717.7 KFQ96200.1 - 0.059 13.4 6.5 2.9 7.9 0.1 5.8 6 1 0 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 KFQ96200.1 - 2.3 8.4 13.1 1.1 9.4 0.3 6.0 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Clat_adaptor_s PF01217.20 KFQ96201.1 - 6.1e-38 130.0 7.5 6.8e-38 129.8 7.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PHD_like PF12910.7 KFQ96201.1 - 0.019 15.0 0.8 0.025 14.6 0.8 1.2 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system WD40 PF00400.32 KFQ96202.1 - 2.1e-36 123.3 10.5 3e-08 34.2 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Striatin PF08232.12 KFQ96202.1 - 3.8e-27 95.8 2.6 3.8e-27 95.8 2.6 2.7 2 1 0 2 2 2 1 Striatin family ANAPC4_WD40 PF12894.7 KFQ96202.1 - 5.6e-08 33.0 0.2 0.11 12.9 0.0 4.9 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFQ96202.1 - 5.1e-05 22.1 0.2 0.79 8.3 0.0 3.7 4 0 0 4 4 4 2 Nucleoporin Nup120/160 VWA PF00092.28 KFQ96203.1 - 2.8e-82 275.2 0.1 1e-41 143.1 0.1 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 KFQ96203.1 - 2e-27 95.9 0.0 2.4e-12 47.4 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain LCCL PF03815.19 KFQ96203.1 - 3e-22 78.5 0.0 7.7e-22 77.2 0.0 1.7 1 0 0 1 1 1 1 LCCL domain VWA_3 PF13768.6 KFQ96203.1 - 1.7e-05 24.8 0.0 0.14 12.1 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain Rxt3 PF08642.10 KFQ96203.1 - 0.12 13.2 0.0 0.32 11.8 0.0 1.7 1 1 0 1 1 1 0 Histone deacetylation protein Rxt3 Sec1 PF00995.23 KFQ96204.1 - 8.8e-123 411.5 1.0 9.8e-123 411.4 1.0 1.0 1 0 0 1 1 1 1 Sec1 family cwf21 PF08312.12 KFQ96204.1 - 0.085 13.0 0.1 0.57 10.4 0.0 2.4 2 0 0 2 2 2 0 cwf21 domain zf-HC5HC2H PF13771.6 KFQ96205.1 - 3.1e-19 69.0 4.1 3.1e-19 69.0 4.1 4.1 3 2 0 3 3 3 1 PHD-like zinc-binding domain HECT PF00632.25 KFQ96205.1 - 3e-08 33.5 0.0 8e-08 32.1 0.0 1.5 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-HC5HC2H_2 PF13832.6 KFQ96205.1 - 1.4e-07 31.6 4.7 1.4e-07 31.6 4.7 4.3 2 2 1 4 4 4 1 PHD-zinc-finger like domain DUF508 PF04370.12 KFQ96206.1 - 0.018 14.8 0.5 0.24 11.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF508) Pkinase PF00069.25 KFQ96208.1 - 2.5e-68 230.3 0.0 3.9e-68 229.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ96208.1 - 1.8e-31 109.4 0.0 3.1e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KFQ96208.1 - 3.6e-29 100.4 19.9 1.1e-14 54.0 7.9 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 KFQ96208.1 - 3.2e-09 37.2 0.0 2.6e-08 34.3 0.0 2.4 2 0 0 2 2 2 1 PH domain C1_2 PF03107.16 KFQ96208.1 - 1.2e-05 25.5 15.0 0.0097 16.2 6.2 2.6 2 0 0 2 2 2 2 C1 domain Kinase-like PF14531.6 KFQ96208.1 - 1.3e-05 24.7 0.1 5.7e-05 22.6 0.0 2.1 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.14 KFQ96208.1 - 0.00056 19.3 0.0 0.0014 18.0 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFQ96208.1 - 0.099 12.2 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 RIO1 family zf-RING_9 PF13901.6 KFQ96208.1 - 0.11 12.4 12.4 1 9.3 0.4 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon PHD PF00628.29 KFQ96208.1 - 0.34 10.9 17.7 1.9 8.5 5.3 2.5 2 0 0 2 2 2 0 PHD-finger FYVE_2 PF02318.16 KFQ96208.1 - 1.4 9.1 10.9 6.9 6.9 5.5 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger PHD_2 PF13831.6 KFQ96208.1 - 7.5 6.2 10.2 12 5.5 0.7 3.0 2 0 0 2 2 2 0 PHD-finger Forkhead PF00250.18 KFQ96209.1 - 6.7e-41 138.4 0.1 7.4e-41 138.3 0.1 1.0 1 0 0 1 1 1 1 Forkhead domain Diphtheria_C PF02763.14 KFQ96209.1 - 0.031 14.0 0.1 0.037 13.7 0.1 1.1 1 0 0 1 1 1 0 Diphtheria toxin, C domain zf_CCCH_4 PF18345.1 KFQ96210.1 - 6.2e-17 61.0 24.5 4.6e-06 26.5 5.7 3.4 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH PF00642.24 KFQ96210.1 - 4.9e-14 51.8 15.9 0.00012 21.9 0.9 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KFQ96210.1 - 1.2e-12 47.3 19.7 1.2e-09 37.7 2.6 3.3 3 0 0 3 3 3 3 CCCH-type zinc finger Torus PF16131.5 KFQ96210.1 - 0.00035 21.2 0.5 0.00035 21.2 0.5 5.0 3 1 2 5 5 5 3 Torus domain zf-CCCH_2 PF14608.6 KFQ96210.1 - 0.012 16.1 22.8 1.1 9.8 3.4 3.5 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KFQ96210.1 - 0.037 14.2 10.7 0.14 12.3 2.2 2.5 1 1 1 2 2 2 0 Zinc-finger containing family ThiF PF00899.21 KFQ96211.1 - 0.01 15.2 0.1 0.01 15.2 0.1 1.1 1 0 0 1 1 1 1 ThiF family LRR_8 PF13855.6 KFQ96212.1 - 3.6e-32 109.9 17.1 7.9e-13 48.0 1.7 3.5 2 1 1 3 3 3 3 Leucine rich repeat I-set PF07679.16 KFQ96212.1 - 2.7e-15 56.2 0.0 4.6e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ96212.1 - 9.7e-14 51.7 0.1 2.1e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin domain LRR_5 PF13306.6 KFQ96212.1 - 7.2e-12 45.4 0.8 1e-06 28.7 0.1 2.3 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFQ96212.1 - 1.3e-10 41.3 19.8 0.0025 18.2 4.1 4.6 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) Ig_2 PF13895.6 KFQ96212.1 - 1.5e-10 41.3 0.0 2.9e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFQ96212.1 - 1.6e-08 34.6 0.0 3.2e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.21 KFQ96212.1 - 7.8e-06 26.1 0.0 1.8e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain LRR_9 PF14580.6 KFQ96212.1 - 4e-05 23.2 7.0 0.0027 17.2 1.3 2.5 1 1 1 2 2 2 2 Leucine-rich repeat V-set PF07686.17 KFQ96212.1 - 0.0017 18.5 0.1 0.67 10.1 0.0 2.4 1 1 1 2 2 2 2 Immunoglobulin V-set domain LRR_1 PF00560.33 KFQ96212.1 - 0.012 16.1 13.1 3.7 8.5 0.9 6.0 6 0 0 6 6 5 0 Leucine Rich Repeat Sigma_reg_N PF13800.6 KFQ96212.1 - 0.22 11.8 2.4 0.5 10.7 2.4 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF3139 PF11337.8 KFQ96212.1 - 0.3 11.8 3.3 0.83 10.3 3.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) EF-hand_1 PF00036.32 KFQ96213.1 - 3e-39 129.6 8.5 3.8e-10 38.6 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFQ96213.1 - 3.1e-33 114.0 1.8 1.9e-15 57.1 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFQ96213.1 - 2.8e-31 107.1 8.3 2e-13 50.0 0.1 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KFQ96213.1 - 3.2e-28 95.2 5.0 9.9e-10 37.6 0.1 4.4 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KFQ96213.1 - 1.3e-25 87.7 5.3 9.9e-07 28.0 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KFQ96213.1 - 9.7e-14 51.4 0.1 1.6e-09 37.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KFQ96213.1 - 1.5e-06 28.1 0.3 0.049 13.6 0.0 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFQ96213.1 - 2.1e-06 28.0 0.0 0.049 13.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 KFQ96213.1 - 8.7e-06 25.7 0.0 0.033 14.2 0.0 2.8 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KFQ96213.1 - 4.2e-05 23.5 0.2 0.00015 21.8 0.0 1.9 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 KFQ96213.1 - 0.00013 22.7 0.0 0.06 14.2 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 KFQ96213.1 - 0.00085 19.5 5.6 0.12 12.6 0.7 3.0 1 1 2 3 3 3 2 Dockerin type I domain Caleosin PF05042.13 KFQ96213.1 - 0.00097 19.1 0.3 0.58 10.1 0.0 3.0 1 1 2 3 3 3 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 KFQ96213.1 - 0.0025 18.1 0.9 1.3 9.3 0.1 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb4 DUF1103 PF06513.11 KFQ96213.1 - 0.0038 16.9 1.8 0.0041 16.8 1.8 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF4497 PF14924.6 KFQ96213.1 - 0.0086 16.5 0.0 0.66 10.5 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) Poly_export PF02563.16 KFQ96213.1 - 0.0089 16.2 0.1 0.66 10.2 0.0 2.9 1 1 2 3 3 3 1 Polysaccharide biosynthesis/export protein EF-hand_14 PF17959.1 KFQ96213.1 - 0.019 15.3 0.1 6.6 7.2 0.0 2.3 1 1 1 2 2 2 0 EF-hand domain TerB PF05099.13 KFQ96213.1 - 0.025 14.6 0.3 0.35 10.8 0.0 2.0 1 1 1 2 2 2 0 Tellurite resistance protein TerB SurA_N_2 PF13623.6 KFQ96213.1 - 0.033 14.0 0.4 2.4 8.0 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain MotA_activ PF09114.10 KFQ96213.1 - 0.05 13.7 0.3 1.1 9.4 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain TetR_C_7 PF14246.6 KFQ96213.1 - 0.054 13.5 0.1 5.7 7.0 0.0 2.7 2 1 1 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain RuvA_C PF07499.13 KFQ96213.1 - 0.079 13.4 0.1 10 6.7 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain dCache_2 PF08269.11 KFQ96213.1 - 0.085 12.0 0.1 6.6 5.8 0.1 2.4 1 1 1 2 2 2 0 Cache domain Fe_hyd_lg_C PF02906.14 KFQ96213.1 - 0.093 12.4 0.3 0.29 10.8 0.3 1.8 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain DUF1811 PF08838.10 KFQ96213.1 - 0.12 12.6 0.0 20 5.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) CMD PF02627.20 KFQ96213.1 - 0.16 12.0 0.2 5.8 7.0 0.0 2.5 1 1 0 2 2 2 0 Carboxymuconolactone decarboxylase family Spore_III_AB PF09548.10 KFQ96213.1 - 0.17 12.0 0.1 0.22 11.6 0.1 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Arf PF00025.21 KFQ96216.1 - 5.8e-36 123.6 0.0 6.7e-36 123.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFQ96216.1 - 2.1e-11 43.7 0.0 2.3e-11 43.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ96216.1 - 2.5e-10 40.6 0.0 3.2e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KFQ96216.1 - 3.8e-06 26.3 0.0 4.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.12 KFQ96216.1 - 3.3e-05 23.3 0.0 3.8e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFQ96216.1 - 0.066 13.3 0.0 0.19 11.8 0.0 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Glyco_hydro_56 PF01630.18 KFQ96217.1 - 2.9e-142 473.6 0.2 3.4e-142 473.4 0.2 1.0 1 0 0 1 1 1 1 Hyaluronidase Glyco_hydro_56 PF01630.18 KFQ96218.1 - 3e-148 493.3 1.0 3.5e-148 493.1 1.0 1.0 1 0 0 1 1 1 1 Hyaluronidase EGF PF00008.27 KFQ96218.1 - 0.0061 16.8 2.5 0.17 12.2 0.0 2.5 2 0 0 2 2 2 1 EGF-like domain Chs7 PF12271.8 KFQ96218.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Chitin synthase export chaperone EGF_2 PF07974.13 KFQ96218.1 - 0.17 12.3 7.0 0.4 11.1 0.5 2.5 2 0 0 2 2 2 0 EGF-like domain WH1 PF00568.23 KFQ96219.1 - 1.7e-36 124.5 0.1 2.4e-36 124.0 0.1 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 KFQ96219.1 - 1.5e-18 66.9 0.4 3.9e-18 65.6 0.1 1.9 2 0 0 2 2 2 1 P21-Rho-binding domain WH2 PF02205.20 KFQ96219.1 - 1.2e-16 59.9 1.7 1.6e-07 30.9 0.1 2.7 2 0 0 2 2 2 2 WH2 motif DUF4918 PF16265.5 KFQ96219.1 - 0.083 12.4 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4918) PQQ PF01011.21 KFQ96219.1 - 0.092 12.7 0.0 0.33 10.9 0.0 2.0 1 0 0 1 1 1 0 PQQ enzyme repeat Tropomodulin PF03250.14 KFQ96220.1 - 1.4e-11 44.7 18.2 1.4e-11 44.7 18.2 2.5 2 0 0 2 2 2 1 Tropomodulin LRR_6 PF13516.6 KFQ96220.1 - 0.003 17.5 0.0 0.0091 16.0 0.0 1.9 1 0 0 1 1 1 1 Leucine Rich repeat WH2 PF02205.20 KFQ96220.1 - 0.012 15.4 0.0 0.039 13.8 0.0 1.9 1 0 0 1 1 1 0 WH2 motif PNISR PF15996.5 KFQ96220.1 - 5.2 7.3 32.5 1.1 9.6 18.1 3.3 3 0 0 3 3 3 0 Arginine/serine-rich protein PNISR Ank_2 PF12796.7 KFQ96221.1 - 1.5e-57 192.1 13.8 1e-11 45.2 0.0 6.3 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ96221.1 - 6e-44 147.9 2.4 2e-09 37.8 0.0 7.7 6 2 3 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ96221.1 - 6.4e-42 136.7 5.0 0.00029 21.0 0.0 11.3 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 KFQ96221.1 - 7.2e-31 105.9 10.5 1.3e-06 28.5 0.1 9.5 3 1 8 11 11 11 9 Ankyrin repeats (many copies) Ank PF00023.30 KFQ96221.1 - 9.8e-28 95.4 12.0 0.04 14.4 0.0 10.7 11 0 0 11 11 11 8 Ankyrin repeat SOCS_box PF07525.16 KFQ96221.1 - 1.5e-11 44.5 7.0 2.6e-10 40.5 9.0 2.0 2 0 0 2 2 2 1 SOCS box ETC_C1_NDUFA5 PF04716.14 KFQ96222.1 - 2.5e-27 94.5 0.4 3.8e-27 93.9 0.4 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Complex1_LYR PF05347.15 KFQ96222.1 - 0.022 14.8 0.1 0.031 14.3 0.1 1.3 1 0 0 1 1 1 0 Complex 1 protein (LYR family) PB1-F2 PF11986.8 KFQ96222.1 - 0.044 14.0 0.1 0.061 13.5 0.1 1.2 1 0 0 1 1 1 0 Influenza A Proapoptotic protein NEL PF14496.6 KFQ96222.1 - 0.077 12.4 0.2 1.8 7.9 0.2 2.1 1 1 0 2 2 2 0 C-terminal novel E3 ligase, LRR-interacting ATP-synt_S1 PF05827.12 KFQ96223.1 - 2.4e-52 176.7 0.3 7.9e-52 175.0 0.0 1.9 2 0 0 2 2 2 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Na_sulph_symp PF00939.19 KFQ96224.1 - 5.5e-94 315.9 32.3 7.1e-94 315.5 32.3 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KFQ96224.1 - 2.7e-23 82.7 48.4 2e-13 50.3 4.9 3.2 2 1 1 3 3 3 3 Citrate transporter REC104 PF17378.2 KFQ96224.1 - 0.16 11.7 0.2 1.8 8.4 0.1 2.1 2 0 0 2 2 2 0 Meiotic recombination protein REC104 Sacchrp_dh_C PF16653.5 KFQ96226.1 - 1.4e-80 271.2 0.0 4.2e-80 269.7 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 KFQ96226.1 - 1.8e-27 96.3 0.4 1.6e-26 93.2 0.0 2.6 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 KFQ96226.1 - 1.5e-23 83.4 0.1 2.6e-23 82.7 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 KFQ96226.1 - 2.7e-08 33.4 0.1 4.2e-05 22.9 0.0 3.2 2 1 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KFQ96226.1 - 0.00031 20.8 0.1 0.00064 19.8 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 KFQ96226.1 - 0.0021 17.4 0.4 0.0092 15.4 0.1 1.9 1 1 1 2 2 2 1 ThiF family DUF2325 PF10087.9 KFQ96226.1 - 0.019 15.0 0.2 0.059 13.5 0.2 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) RrnaAD PF00398.20 KFQ96226.1 - 0.14 11.2 0.5 0.6 9.1 0.3 1.9 1 1 1 2 2 2 0 Ribosomal RNA adenine dimethylase Y_phosphatase PF00102.27 KFQ96227.1 - 3.6e-146 484.9 7.2 2.9e-86 288.9 1.5 2.8 3 0 0 3 3 3 2 Protein-tyrosine phosphatase Carb_anhydrase PF00194.21 KFQ96227.1 - 1.4e-73 247.5 0.2 2.5e-73 246.7 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase fn3 PF00041.21 KFQ96227.1 - 6.7e-12 45.6 0.1 2.5e-11 43.8 0.1 2.1 1 0 0 1 1 1 1 Fibronectin type III domain DSPc PF00782.20 KFQ96227.1 - 0.00092 19.0 1.6 0.02 14.7 0.0 3.4 4 0 0 4 4 4 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFQ96227.1 - 0.0046 17.0 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFQ96227.1 - 0.061 13.4 0.1 0.3 11.2 0.0 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate Orf78 PF06024.12 KFQ96227.1 - 1.3 9.3 3.4 0.75 10.1 0.0 2.3 2 0 0 2 2 2 0 Orf78 (ac78) ILEI PF15711.5 KFQ96229.1 - 2.5e-28 98.4 0.0 3.7e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Interleukin-like EMT inducer ING PF12998.7 KFQ96232.1 - 6.5e-16 58.8 2.8 1.8e-15 57.3 2.8 1.8 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KFQ96232.1 - 1.4e-06 28.1 7.3 2.8e-06 27.1 7.3 1.5 1 0 0 1 1 1 1 PHD-finger Pet100 PF09803.9 KFQ96232.1 - 0.074 13.6 1.3 0.2 12.2 1.3 1.7 1 0 0 1 1 1 0 Pet100 SAICAR_synt PF01259.18 KFQ96232.1 - 0.12 11.9 1.0 0.19 11.3 1.0 1.2 1 0 0 1 1 1 0 SAICAR synthetase zf-HC5HC2H PF13771.6 KFQ96232.1 - 0.14 12.4 2.0 0.37 11.1 2.0 1.9 1 1 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 KFQ96232.1 - 0.29 10.7 3.0 0.57 9.8 3.0 1.5 1 0 0 1 1 1 0 PHD-finger Tetraspanin PF00335.20 KFQ96233.1 - 1e-32 113.7 7.4 1.2e-32 113.5 7.4 1.1 1 0 0 1 1 1 1 Tetraspanin family SUR7 PF06687.12 KFQ96233.1 - 0.15 11.7 4.3 0.11 12.1 2.4 1.7 2 0 0 2 2 2 0 SUR7/PalI family MscS_TM PF12794.7 KFQ96233.1 - 4 6.2 9.0 0.42 9.4 4.5 1.6 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 DUF3399 PF11879.8 KFQ96234.1 - 1.6e-42 144.0 10.4 1.6e-42 144.0 10.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3399) Ion_trans PF00520.31 KFQ96234.1 - 2.1e-06 27.1 0.0 2.8e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFQ96234.1 - 0.001 19.0 0.1 0.0015 18.5 0.1 1.3 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 KFQ96235.1 - 1.5e-28 99.7 11.9 2e-28 99.3 11.9 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFQ96235.1 - 8.3e-28 96.6 0.1 2.3e-27 95.2 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Shal-type PF11601.8 KFQ96235.1 - 2.6e-13 49.3 14.9 4.6e-13 48.4 14.9 1.4 1 0 0 1 1 1 1 Shal-type voltage-gated potassium channels, N-terminal BTB_3 PF16017.5 KFQ96235.1 - 0.0012 19.0 0.0 0.0036 17.4 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFQ96235.1 - 0.017 15.1 4.0 0.017 15.1 4.0 2.8 3 0 0 3 3 3 0 Ion channel PKD_channel PF08016.12 KFQ96235.1 - 0.075 11.7 9.9 0.13 10.9 9.9 1.5 1 1 0 1 1 1 0 Polycystin cation channel zf-C2H2 PF00096.26 KFQ96237.1 - 1.8e-12 47.0 12.7 2.3e-07 30.9 2.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ96237.1 - 4.1e-12 45.9 13.2 2.4e-08 34.0 2.3 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ96237.1 - 7.1e-07 29.5 11.1 0.00089 19.9 1.6 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFQ96237.1 - 0.0009 19.3 1.4 0.0015 18.6 1.4 1.4 1 1 0 1 1 1 1 Zinc ribbon domain zf-C2H2_6 PF13912.6 KFQ96237.1 - 0.0013 18.6 10.4 0.13 12.3 2.6 2.5 2 1 0 2 2 2 2 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 KFQ96237.1 - 0.0043 16.9 0.7 0.009 15.9 0.7 1.6 1 1 0 1 1 1 1 SprT-like zinc ribbon domain zf-C2H2_11 PF16622.5 KFQ96237.1 - 0.0062 16.3 7.8 0.072 12.9 0.8 2.3 2 1 0 2 2 2 2 zinc-finger C2H2-type CpXC PF14353.6 KFQ96237.1 - 0.0076 16.3 0.6 0.27 11.3 0.1 2.0 1 1 1 2 2 2 1 CpXC protein zf_UBZ PF18439.1 KFQ96237.1 - 0.014 15.0 1.2 3.7 7.2 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_9 PF14369.6 KFQ96237.1 - 0.018 15.3 1.5 2.8 8.3 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon zf-C2H2_jaz PF12171.8 KFQ96237.1 - 0.019 15.2 1.7 4.4 7.7 0.4 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding XPA_N PF01286.18 KFQ96237.1 - 0.024 14.7 1.0 2.6 8.2 0.1 2.2 2 0 0 2 2 2 0 XPA protein N-terminal DZR PF12773.7 KFQ96237.1 - 0.026 14.6 1.2 0.045 13.8 1.2 1.4 1 1 0 1 1 1 0 Double zinc ribbon zf-ISL3 PF14690.6 KFQ96237.1 - 0.031 14.9 1.6 0.5 11.1 0.2 2.2 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-ribbon_3 PF13248.6 KFQ96237.1 - 0.033 13.6 1.9 2.8 7.5 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-met PF12874.7 KFQ96237.1 - 0.036 14.5 4.2 2.6 8.5 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.6 KFQ96237.1 - 0.045 14.3 1.4 2.7 8.6 1.4 2.1 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain YhfH PF14149.6 KFQ96237.1 - 0.047 13.7 1.1 5.8 7.0 0.1 2.3 2 0 0 2 2 2 0 YhfH-like protein zf-C2H2_8 PF15909.5 KFQ96237.1 - 0.07 13.4 1.7 0.076 13.3 1.7 1.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon HalOD2 PF18547.1 KFQ96237.1 - 0.084 12.8 2.4 0.43 10.5 0.3 2.1 2 0 0 2 2 2 0 Halobacterial output domain 2 DUF2256 PF10013.9 KFQ96237.1 - 0.11 12.6 2.1 6 7.1 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) TF_Zn_Ribbon PF08271.12 KFQ96237.1 - 0.24 10.9 2.8 1.7 8.2 0.1 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding Rubredoxin_2 PF18073.1 KFQ96237.1 - 0.26 11.0 2.9 8.7 6.2 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zinc_ribbon_2 PF13240.6 KFQ96237.1 - 0.32 10.8 4.9 3.4 7.5 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_3 PF13878.6 KFQ96237.1 - 0.47 10.3 11.8 0.5 10.2 2.8 3.4 2 1 1 3 3 3 0 zinc-finger of acetyl-transferase ESCO UPF0547 PF10571.9 KFQ96237.1 - 0.58 10.3 5.4 0.83 9.8 0.3 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DUF2072 PF09845.9 KFQ96237.1 - 0.73 10.1 3.5 0.95 9.7 0.3 2.0 2 0 0 2 2 2 0 Zn-ribbon containing protein OrfB_Zn_ribbon PF07282.11 KFQ96237.1 - 0.78 9.7 2.8 2 8.4 2.8 1.7 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf-H2C2_2 PF13465.6 KFQ96238.1 - 1e-44 149.0 29.6 1.1e-09 38.2 0.4 6.2 6 0 0 6 6 6 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ96238.1 - 4.6e-31 105.5 39.6 1e-06 28.9 1.1 6.2 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ96238.1 - 6.2e-22 76.4 38.9 0.0018 18.9 0.4 6.1 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ96238.1 - 7.5e-12 45.2 11.3 1.3 9.4 0.0 6.4 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KFQ96238.1 - 1.7e-10 40.9 19.9 8.9e-05 22.5 1.2 4.6 3 2 2 5 5 5 3 Zinc ribbon domain zf-C2H2_6 PF13912.6 KFQ96238.1 - 4.2e-09 36.2 44.7 0.0013 18.6 0.2 7.8 7 2 0 7 7 7 4 C2H2-type zinc finger zf-met PF12874.7 KFQ96238.1 - 7.6e-08 32.5 22.9 0.24 11.8 0.1 6.3 6 0 0 6 6 6 3 Zinc-finger of C2H2 type Prok-RING_1 PF14446.6 KFQ96238.1 - 2.7e-06 27.2 16.0 0.5 10.3 2.2 5.9 5 1 0 5 5 5 1 Prokaryotic RING finger family 1 zf_UBZ PF18439.1 KFQ96238.1 - 1.4e-05 24.5 20.2 0.2 11.3 0.1 6.3 6 0 0 6 6 6 1 Ubiquitin-Binding Zinc Finger ADK_lid PF05191.14 KFQ96238.1 - 2e-05 24.5 15.7 0.3 11.1 0.4 4.8 3 2 2 5 5 5 3 Adenylate kinase, active site lid DZR PF12773.7 KFQ96238.1 - 4e-05 23.5 13.6 60 3.8 13.6 3.6 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 KFQ96238.1 - 4.1e-05 24.2 10.4 0.33 11.7 0.5 3.1 2 1 1 3 3 3 2 zinc-ribbon family zf-Di19 PF05605.12 KFQ96238.1 - 4.5e-05 23.6 18.5 0.019 15.3 1.4 3.6 1 1 2 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding XPA_N PF01286.18 KFQ96238.1 - 0.00012 22.0 20.7 4.1 7.5 0.0 6.3 6 1 0 6 6 6 0 XPA protein N-terminal CpXC PF14353.6 KFQ96238.1 - 0.00014 21.9 13.6 2 8.5 0.1 5.7 2 2 3 6 6 6 1 CpXC protein HypA PF01155.19 KFQ96238.1 - 0.00019 21.4 11.0 0.37 10.8 0.4 3.2 1 1 1 3 3 3 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2256 PF10013.9 KFQ96238.1 - 0.00023 21.2 18.8 0.16 12.1 0.5 6.0 6 0 0 6 6 6 1 Uncharacterized protein conserved in bacteria (DUF2256) YhfH PF14149.6 KFQ96238.1 - 0.00035 20.5 16.0 6.2 6.9 0.0 6.1 6 0 0 6 6 6 0 YhfH-like protein FYDLN_acid PF09538.10 KFQ96238.1 - 0.00037 21.1 8.4 1.6 9.5 0.1 5.3 1 1 5 6 6 6 1 Protein of unknown function (FYDLN_acid) zinc-ribbons_6 PF07191.12 KFQ96238.1 - 0.00046 20.1 14.2 1.6 8.7 0.2 4.3 2 1 2 4 4 4 3 zinc-ribbons zf-trcl PF13451.6 KFQ96238.1 - 0.00058 19.7 19.0 2.3 8.2 0.1 6.1 6 0 0 6 6 6 1 Probable zinc-ribbon domain Zf_RING PF16744.5 KFQ96238.1 - 0.0011 19.1 11.6 7.2 6.8 0.0 5.1 1 1 4 5 5 5 0 KIAA1045 RING finger LIM PF00412.22 KFQ96238.1 - 0.0017 18.5 15.4 2.4 8.4 2.4 4.9 1 1 4 5 5 5 1 LIM domain C1_4 PF07975.12 KFQ96238.1 - 0.0055 16.9 16.6 1.3 9.3 1.2 4.5 2 2 2 4 4 4 2 TFIIH C1-like domain DUF3268 PF11672.8 KFQ96238.1 - 0.0057 17.0 11.2 0.65 10.3 0.5 3.3 2 1 2 4 4 4 3 zinc-finger-containing domain BolA PF01722.18 KFQ96238.1 - 0.0068 16.7 1.5 4.6 7.6 0.1 3.6 2 2 0 2 2 2 0 BolA-like protein zf-LYAR PF08790.11 KFQ96238.1 - 0.0086 16.0 22.3 0.22 11.5 0.1 5.7 6 0 0 6 6 6 2 LYAR-type C2HC zinc finger zf-C2H2_11 PF16622.5 KFQ96238.1 - 0.013 15.2 25.2 0.23 11.3 0.3 6.0 6 0 0 6 6 6 0 zinc-finger C2H2-type Zn-C2H2_12 PF18112.1 KFQ96238.1 - 0.017 15.6 12.5 1 9.9 0.6 5.0 5 0 0 5 5 5 0 Autophagy receptor zinc finger-C2H2 domain PHF5 PF03660.14 KFQ96238.1 - 0.022 15.0 6.5 0.59 10.4 0.1 3.2 1 1 2 3 3 3 0 PHF5-like protein zf-C2HC_2 PF13913.6 KFQ96238.1 - 0.023 14.6 29.7 4.8 7.2 1.2 6.6 6 1 0 6 6 6 0 zinc-finger of a C2HC-type zf-RING_5 PF14634.6 KFQ96238.1 - 0.029 14.3 15.2 2.3 8.3 1.2 4.7 2 2 1 3 3 3 0 zinc-RING finger domain zf-AN1 PF01428.16 KFQ96238.1 - 0.029 14.5 28.4 9.4 6.5 0.5 6.4 5 1 1 6 6 6 0 AN1-like Zinc finger zinc_ribbon_9 PF14369.6 KFQ96238.1 - 0.03 14.6 1.3 0.66 10.3 0.1 5.0 6 0 0 6 6 5 0 zinc-ribbon FYVE PF01363.21 KFQ96238.1 - 0.034 14.3 23.4 6.8 6.9 9.8 4.4 1 1 1 2 2 2 0 FYVE zinc finger zf_C2H2_ZHX PF18387.1 KFQ96238.1 - 0.067 12.8 14.7 1.5 8.5 0.1 4.2 2 2 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain MRP-S23 PF10484.9 KFQ96238.1 - 0.085 13.1 0.0 50 4.2 0.0 3.2 3 1 1 4 4 3 0 Mitochondrial ribosomal protein S23 Metallothio_Pro PF02069.16 KFQ96238.1 - 0.16 12.2 16.5 3.2 8.1 0.1 5.0 2 2 2 5 5 5 0 Prokaryotic metallothionein zf-UBR PF02207.20 KFQ96238.1 - 0.17 12.0 18.1 0.14 12.3 7.2 3.4 2 2 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) DUF2072 PF09845.9 KFQ96238.1 - 0.2 11.9 18.6 2.1 8.6 0.2 4.9 4 2 0 4 4 4 0 Zn-ribbon containing protein TFIIS_C PF01096.18 KFQ96238.1 - 0.27 11.1 21.2 24 4.9 0.1 6.1 6 0 0 6 6 6 0 Transcription factor S-II (TFIIS) TF_Zn_Ribbon PF08271.12 KFQ96238.1 - 0.59 9.7 21.9 0.42 10.2 1.4 5.3 5 1 0 5 5 5 0 TFIIB zinc-binding DUF4428 PF14471.6 KFQ96238.1 - 0.73 9.8 11.4 0.86 9.6 0.2 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4428) A2L_zn_ribbon PF08792.10 KFQ96238.1 - 0.89 9.3 0.0 0.89 9.3 0.0 5.4 6 0 0 6 6 5 0 A2L zinc ribbon domain Chordopox_RPO7 PF05864.12 KFQ96238.1 - 1 9.7 6.5 2.5 8.4 0.0 4.0 6 0 0 6 6 3 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) zf-C2H2_3rep PF18868.1 KFQ96238.1 - 2 9.1 17.9 5.7 7.6 6.2 4.8 1 1 3 4 4 4 0 Zinc finger C2H2-type, 3 repeats DUF2039 PF10217.9 KFQ96238.1 - 2.5 8.5 14.1 0.58 10.5 0.6 3.1 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2039) Rad50_zn_hook PF04423.14 KFQ96238.1 - 3.3 7.6 13.9 1.9 8.4 0.5 4.3 3 1 1 4 4 4 0 Rad50 zinc hook motif zf-C2HE PF16278.5 KFQ96238.1 - 3.6 8.1 23.5 8.8 6.9 0.5 5.6 3 3 3 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger Zn_ribbon_SprT PF17283.2 KFQ96238.1 - 3.6 7.6 27.5 0.52 10.3 4.3 5.5 3 2 2 5 5 5 0 SprT-like zinc ribbon domain zinc_ribbon_4 PF13717.6 KFQ96238.1 - 3.8 7.5 21.3 26 4.8 2.7 5.8 4 2 1 5 5 5 0 zinc-ribbon domain DUF2175 PF09943.9 KFQ96238.1 - 4.3 7.7 10.8 37 4.7 0.0 4.7 6 0 0 6 6 5 0 Uncharacterized protein conserved in archaea (DUF2175) zf_ZIC PF18366.1 KFQ96238.1 - 5.7 7.1 14.6 2.4 8.3 0.1 4.8 2 2 4 6 6 6 0 Zic proteins zinc finger domain IBR PF01485.21 KFQ96238.1 - 6.6 7.0 24.8 43 4.4 0.4 4.5 1 1 3 4 4 4 0 IBR domain, a half RING-finger domain Mut7-C PF01927.16 KFQ96238.1 - 7.5 6.7 16.6 5.3 7.1 0.4 4.7 1 1 4 5 5 5 0 Mut7-C RNAse domain zf-HIT PF04438.16 KFQ96238.1 - 8.2 6.4 26.1 16 5.5 0.2 6.0 6 0 0 6 6 6 0 HIT zinc finger GAGA PF09237.11 KFQ96238.1 - 9.6 6.1 15.5 15 5.5 0.2 4.6 2 2 2 4 4 4 0 GAGA factor PRY PF13765.6 KFQ96239.1 - 1.9e-17 62.6 0.0 3.3e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.28 KFQ96239.1 - 1.1e-08 35.3 0.0 1.3e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 SPRY domain V-set PF07686.17 KFQ96240.1 - 5.3e-06 26.6 0.0 5.6e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain zf-H2C2_2 PF13465.6 KFQ96241.1 - 3.6e-71 232.6 80.6 3.1e-09 36.8 2.1 12.2 12 0 0 12 12 12 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ96241.1 - 1.2e-65 214.5 87.4 3.7e-06 27.1 0.2 12.1 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ96241.1 - 2.3e-48 158.7 81.7 0.00018 22.1 0.7 12.1 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFQ96241.1 - 1.6e-17 63.0 79.0 0.0005 20.0 1.4 12.3 12 1 0 12 12 12 6 C2H2-type zinc finger zf_UBZ PF18439.1 KFQ96241.1 - 8.6e-17 60.4 41.7 0.044 13.4 0.0 12.1 12 0 0 12 12 12 6 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 KFQ96241.1 - 9.9e-16 57.2 61.0 0.065 13.0 0.1 11.8 12 0 0 12 12 12 8 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFQ96241.1 - 3.7e-14 52.6 38.2 0.03 14.6 0.2 11.8 12 0 0 12 12 12 3 Zinc-finger double-stranded RNA-binding DZR PF12773.7 KFQ96241.1 - 1.4e-12 47.4 47.0 0.0023 17.9 0.2 7.0 3 2 1 4 4 4 2 Double zinc ribbon zinc_ribbon_15 PF17032.5 KFQ96241.1 - 4.3e-11 43.4 41.9 0.013 16.2 1.1 6.1 3 1 3 6 6 6 5 zinc-ribbon family Zn-ribbon_8 PF09723.10 KFQ96241.1 - 5.9e-11 42.3 59.8 0.0018 18.3 1.2 8.8 2 2 9 11 11 11 7 Zinc ribbon domain CpXC PF14353.6 KFQ96241.1 - 9.6e-09 35.3 40.5 0.2 11.7 0.7 11.1 4 3 7 11 11 11 3 CpXC protein LIM PF00412.22 KFQ96241.1 - 3.9e-08 33.4 42.6 0.026 14.7 0.4 7.8 4 3 2 7 7 7 3 LIM domain zf-C2HC_2 PF13913.6 KFQ96241.1 - 3.9e-07 29.8 56.5 0.073 13.0 0.2 10.8 11 0 0 11 11 10 4 zinc-finger of a C2HC-type zf-met PF12874.7 KFQ96241.1 - 6.1e-07 29.6 59.4 0.79 10.2 0.3 11.5 12 0 0 12 12 11 4 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFQ96241.1 - 6.8e-07 29.5 47.3 0.00015 22.0 1.0 7.3 4 3 3 8 8 7 3 Drought induced 19 protein (Di19), zinc-binding MCM_OB PF17207.3 KFQ96241.1 - 7.3e-06 25.8 27.5 0.55 10.1 4.8 5.3 1 1 4 5 5 5 4 MCM OB domain Zn_ribbon_SprT PF17283.2 KFQ96241.1 - 9.8e-06 25.4 58.4 0.0079 16.1 0.2 9.4 5 3 5 10 10 8 4 SprT-like zinc ribbon domain zf-LYAR PF08790.11 KFQ96241.1 - 1.1e-05 25.2 52.4 0.9 9.5 0.1 11.6 12 0 0 12 12 12 3 LYAR-type C2HC zinc finger DUF3268 PF11672.8 KFQ96241.1 - 6.3e-05 23.3 30.3 0.045 14.1 0.2 6.4 3 2 4 7 7 7 2 zinc-finger-containing domain C1_4 PF07975.12 KFQ96241.1 - 0.00019 21.6 45.6 0.38 11.0 1.1 7.4 3 2 6 9 9 9 3 TFIIH C1-like domain FYDLN_acid PF09538.10 KFQ96241.1 - 0.00022 21.8 35.7 5.7 7.7 0.1 10.3 1 1 6 9 9 9 0 Protein of unknown function (FYDLN_acid) HypA PF01155.19 KFQ96241.1 - 0.0005 20.1 39.7 0.13 12.3 0.2 6.5 1 1 4 5 5 5 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS1595 PF12760.7 KFQ96241.1 - 0.00056 19.8 63.2 0.23 11.5 2.6 7.5 4 1 2 7 7 7 5 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.12 KFQ96241.1 - 0.0042 16.6 0.7 0.0042 16.6 0.7 9.6 9 3 0 9 9 9 1 TFIIB zinc-binding zf-AN1 PF01428.16 KFQ96241.1 - 0.02 15.1 60.8 8 6.7 0.1 12.0 10 1 2 12 12 12 0 AN1-like Zinc finger Trm112p PF03966.16 KFQ96241.1 - 0.021 15.4 0.3 0.021 15.4 0.3 5.0 5 3 0 5 5 4 0 Trm112p-like protein Terminase_GpA PF05876.12 KFQ96241.1 - 0.024 13.2 29.3 0.038 12.5 0.3 4.5 2 2 1 4 4 4 0 Phage terminase large subunit (GpA) Zn_ribbon_recom PF13408.6 KFQ96241.1 - 0.025 15.1 51.2 2.9 8.5 0.3 8.6 3 3 6 9 9 9 0 Recombinase zinc beta ribbon domain YhfH PF14149.6 KFQ96241.1 - 0.026 14.5 40.3 17 5.5 0.0 9.8 11 0 0 11 11 9 0 YhfH-like protein BDHCT_assoc PF16204.5 KFQ96241.1 - 0.028 14.1 10.6 7.4 6.2 2.8 3.9 1 1 4 5 5 5 0 BDHCT-box associated domain on Bloom syndrome protein Zn-C2H2_12 PF18112.1 KFQ96241.1 - 0.029 14.8 0.3 0.029 14.8 0.3 7.0 8 0 0 8 8 6 0 Autophagy receptor zinc finger-C2H2 domain DUF555 PF04475.12 KFQ96241.1 - 0.031 14.6 3.1 15 6.0 0.0 4.8 1 1 5 6 6 6 0 Protein of unknown function (DUF555) zf-DNA_Pol PF08996.10 KFQ96241.1 - 0.043 13.6 41.4 0.13 12.0 0.5 5.8 2 2 5 7 7 7 0 DNA Polymerase alpha zinc finger ADK_lid PF05191.14 KFQ96241.1 - 0.11 12.5 40.7 0.47 10.5 0.5 8.1 5 3 1 6 6 5 0 Adenylate kinase, active site lid Ogr_Delta PF04606.12 KFQ96241.1 - 0.11 12.4 0.4 0.11 12.4 0.4 8.4 6 2 1 8 8 7 0 Ogr/Delta-like zinc finger zf-C4_Topoisom PF01396.19 KFQ96241.1 - 0.12 12.2 25.1 2.6 7.9 0.1 7.4 7 0 0 7 7 7 0 Topoisomerase DNA binding C4 zinc finger PyrI_C PF02748.15 KFQ96241.1 - 0.12 12.3 0.2 0.12 12.3 0.2 7.2 9 1 0 9 9 7 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-ribbon_3 PF13248.6 KFQ96241.1 - 0.15 11.6 53.7 1.1 8.7 0.3 11.4 12 0 0 12 12 12 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 KFQ96241.1 - 0.66 9.9 49.7 2.5 8.1 1.1 11.3 9 3 0 9 9 9 0 zinc-ribbon domain zf-trcl PF13451.6 KFQ96241.1 - 0.87 9.5 56.5 11 6.0 0.0 10.7 9 2 2 11 11 11 0 Probable zinc-ribbon domain zf-C2H2_9 PF16293.5 KFQ96241.1 - 1.4 8.8 0.0 1.4 8.8 0.0 6.7 8 1 1 9 9 8 0 C2H2 type zinc-finger (1 copy) GM_CSF PF01109.17 KFQ96241.1 - 1.9 8.7 6.0 2 8.6 0.1 2.4 2 0 0 2 2 2 0 Granulocyte-macrophage colony-stimulating factor zf-dskA_traR PF01258.17 KFQ96241.1 - 2 8.4 39.6 6.5 6.8 0.7 9.4 10 0 0 10 10 9 0 Prokaryotic dksA/traR C4-type zinc finger TFIIS_C PF01096.18 KFQ96241.1 - 2.3 8.1 51.0 6.4 6.7 3.0 11.4 11 1 0 11 11 11 0 Transcription factor S-II (TFIIS) PRP21_like_P PF12230.8 KFQ96241.1 - 3.5 7.5 5.9 1.1 9.1 0.1 2.7 3 0 0 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein zf-HIT PF04438.16 KFQ96241.1 - 3.9 7.4 58.9 1.1 9.2 0.1 11.2 12 0 0 12 12 12 0 HIT zinc finger zinc-ribbons_6 PF07191.12 KFQ96241.1 - 7.9 6.5 48.1 13 5.9 1.7 7.7 1 1 2 3 3 1 0 zinc-ribbons DUF2089 PF09862.9 KFQ96241.1 - 8.2 6.5 7.1 34 4.5 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2089) DNA_ligase_ZBD PF03119.16 KFQ96241.1 - 9.8 6.3 23.7 9.3 6.4 0.0 6.4 6 0 0 6 6 6 0 NAD-dependent DNA ligase C4 zinc finger domain V-set PF07686.17 KFQ96242.1 - 3.7e-14 52.8 0.0 4.3e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFQ96242.1 - 1.6e-06 28.7 0.0 2.6e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ96242.1 - 6.6e-05 22.9 0.0 0.00015 21.7 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFQ96242.1 - 0.01 16.0 0.0 0.029 14.5 0.0 1.7 1 1 0 1 1 1 0 Immunoglobulin domain V-set_CD47 PF08204.11 KFQ96242.1 - 0.06 13.3 0.0 0.077 13.0 0.0 1.1 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain zf-H2C2_2 PF13465.6 KFQ96243.1 - 2.6e-90 293.2 105.5 1.3e-09 38.0 0.4 13.1 13 1 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ96243.1 - 4e-70 228.6 105.3 2e-07 31.0 1.2 12.6 12 1 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ96243.1 - 2.3e-39 130.6 99.4 0.0015 19.2 1.0 12.5 12 1 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFQ96243.1 - 1.8e-19 69.2 93.0 0.0034 17.3 2.0 12.4 12 0 0 12 12 12 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ96243.1 - 9.4e-17 60.8 51.0 0.25 11.7 0.1 12.3 13 0 0 13 13 12 6 Zinc-finger double-stranded RNA-binding C1_4 PF07975.12 KFQ96243.1 - 1.5e-13 50.7 53.3 0.0092 16.2 1.1 9.8 2 2 4 8 8 8 6 TFIIH C1-like domain Zn-ribbon_8 PF09723.10 KFQ96243.1 - 1.1e-11 44.6 70.2 0.0025 17.9 2.9 8.2 4 3 5 9 9 9 7 Zinc ribbon domain zf_UBZ PF18439.1 KFQ96243.1 - 9.1e-11 41.2 63.5 0.17 11.5 0.1 12.2 12 0 0 12 12 12 9 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 KFQ96243.1 - 1.2e-06 28.7 62.2 0.52 10.8 0.9 12.1 12 0 0 12 12 12 3 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 KFQ96243.1 - 1.9e-06 28.5 46.0 0.34 11.7 3.5 6.4 2 2 5 7 7 7 6 zinc-ribbon family XPA_N PF01286.18 KFQ96243.1 - 2.6e-06 27.3 64.0 0.84 9.7 0.1 12.1 12 0 0 12 12 12 5 XPA protein N-terminal DUF3268 PF11672.8 KFQ96243.1 - 2.7e-05 24.5 36.0 0.075 13.4 0.7 6.6 2 1 4 8 8 8 3 zinc-finger-containing domain zf-AN1 PF01428.16 KFQ96243.1 - 0.00013 22.1 68.6 2.1 8.6 4.2 12.0 11 1 1 12 12 12 3 AN1-like Zinc finger LIM PF00412.22 KFQ96243.1 - 0.00035 20.7 62.5 1 9.6 2.8 9.7 2 2 5 8 8 8 5 LIM domain DUF4934 PF16288.5 KFQ96243.1 - 0.024 14.6 12.5 5.3 7.0 0.1 5.6 1 1 3 5 5 5 0 Domain of unknown function (DUF4934) zf-trcl PF13451.6 KFQ96243.1 - 0.048 13.6 58.9 12 5.9 0.1 11.6 10 2 0 10 10 10 0 Probable zinc-ribbon domain zf-C2H2_11 PF16622.5 KFQ96243.1 - 0.056 13.2 59.1 0.083 12.7 1.0 11.7 12 0 0 12 12 12 0 zinc-finger C2H2-type HypA PF01155.19 KFQ96243.1 - 0.3 11.1 46.1 7.2 6.7 2.5 6.7 1 1 4 5 5 5 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2HE PF16278.5 KFQ96243.1 - 0.31 11.5 75.3 0.65 10.5 1.0 11.6 3 2 8 11 11 11 0 C2HE / C2H2 / C2HC zinc-binding finger CpXC PF14353.6 KFQ96243.1 - 0.75 9.9 46.0 0.96 9.5 0.2 10.5 5 2 5 10 10 10 0 CpXC protein Prok-RING_1 PF14446.6 KFQ96243.1 - 1.5 8.8 0.0 1.5 8.8 0.0 10.4 7 5 1 8 8 8 0 Prokaryotic RING finger family 1 BDHCT_assoc PF16204.5 KFQ96243.1 - 2 8.1 5.0 14 5.3 0.3 2.9 2 1 0 3 3 3 0 BDHCT-box associated domain on Bloom syndrome protein zf-C2H2 PF00096.26 KFQ96244.1 - 2.5e-17 62.3 8.9 8.3e-09 35.4 1.0 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ96244.1 - 1.5e-15 56.8 12.6 4.6e-09 36.3 1.3 3.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ96244.1 - 8.2e-13 48.0 7.3 9.4e-07 29.2 0.7 2.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFQ96244.1 - 2.7e-12 46.3 7.6 2e-06 27.7 1.6 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ96244.1 - 4.8e-08 33.1 1.8 0.00056 20.1 0.1 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFQ96244.1 - 8.3e-06 25.5 3.8 0.0009 19.0 0.4 2.1 2 0 0 2 2 2 2 zinc-finger C2H2-type zf_UBZ PF18439.1 KFQ96244.1 - 2.8e-05 23.6 1.4 0.071 12.7 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFQ96244.1 - 0.00011 22.2 4.5 0.0018 18.3 4.7 2.1 1 1 1 2 2 2 2 Zinc ribbon domain XPA_N PF01286.18 KFQ96244.1 - 0.0003 20.8 3.1 0.1 12.7 0.2 2.1 2 0 0 2 2 2 2 XPA protein N-terminal CpXC PF14353.6 KFQ96244.1 - 0.0015 18.6 0.6 0.75 9.9 0.0 2.0 2 0 0 2 2 2 1 CpXC protein TF_Zn_Ribbon PF08271.12 KFQ96244.1 - 0.0017 17.8 0.7 0.32 10.6 0.1 2.2 2 0 0 2 2 2 1 TFIIB zinc-binding zinc_ribbon_15 PF17032.5 KFQ96244.1 - 0.0033 18.1 0.9 0.0039 17.9 0.9 1.1 1 0 0 1 1 1 1 zinc-ribbon family YhfH PF14149.6 KFQ96244.1 - 0.0034 17.3 2.8 1.2 9.2 0.1 2.2 2 0 0 2 2 2 2 YhfH-like protein zf-Di19 PF05605.12 KFQ96244.1 - 0.0035 17.6 1.8 0.0054 17.0 1.7 1.4 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding C1_4 PF07975.12 KFQ96244.1 - 0.0043 17.3 1.5 0.038 14.2 1.5 1.9 1 1 0 1 1 1 1 TFIIH C1-like domain Zn_ribbon_SprT PF17283.2 KFQ96244.1 - 0.0046 16.8 2.6 0.01 15.8 2.6 1.6 1 1 0 1 1 1 1 SprT-like zinc ribbon domain zf-LYAR PF08790.11 KFQ96244.1 - 0.0053 16.6 1.1 2.9 7.9 0.0 2.3 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger Prok-RING_1 PF14446.6 KFQ96244.1 - 0.0058 16.5 0.1 2.3 8.2 0.0 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-met PF12874.7 KFQ96244.1 - 0.0068 16.8 3.4 0.44 11.0 0.1 2.4 1 1 2 3 3 3 1 Zinc-finger of C2H2 type Yippee-Mis18 PF03226.14 KFQ96244.1 - 0.0072 16.5 0.6 2.1 8.6 0.1 2.0 1 1 1 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C2HC_2 PF13913.6 KFQ96244.1 - 0.011 15.6 4.6 0.11 12.4 0.5 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DNA_RNApol_7kD PF03604.13 KFQ96244.1 - 0.012 15.3 1.0 3.4 7.4 0.1 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit ADK_lid PF05191.14 KFQ96244.1 - 0.016 15.2 0.9 0.016 15.2 0.9 1.8 2 1 0 2 2 1 0 Adenylate kinase, active site lid zf-C2HE PF16278.5 KFQ96244.1 - 0.017 15.5 4.3 0.044 14.2 0.9 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-HIT PF04438.16 KFQ96244.1 - 0.018 14.9 3.7 2 8.4 0.3 2.2 2 0 0 2 2 2 0 HIT zinc finger TFIIS_C PF01096.18 KFQ96244.1 - 0.02 14.7 3.6 2.4 8.1 0.3 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf_C2H2_ZHX PF18387.1 KFQ96244.1 - 0.023 14.3 2.8 1.9 8.2 0.3 2.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain DZR PF12773.7 KFQ96244.1 - 0.024 14.6 2.3 0.039 14.0 2.3 1.4 1 1 0 1 1 1 0 Double zinc ribbon DUF3268 PF11672.8 KFQ96244.1 - 0.027 14.8 0.4 0.027 14.8 0.4 1.1 1 0 0 1 1 1 0 zinc-finger-containing domain FYDLN_acid PF09538.10 KFQ96244.1 - 0.029 15.1 0.3 1.9 9.2 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) Ribosomal_S27e PF01667.17 KFQ96244.1 - 0.03 14.0 0.5 2.8 7.7 0.1 2.1 2 0 0 2 2 2 0 Ribosomal protein S27 zinc_ribbon_4 PF13717.6 KFQ96244.1 - 0.031 14.2 3.3 0.47 10.4 3.3 2.1 1 1 1 2 2 2 0 zinc-ribbon domain FOXP-CC PF16159.5 KFQ96244.1 - 0.037 14.6 0.5 0.76 10.4 0.1 2.0 1 1 1 2 2 2 0 FOXP coiled-coil domain zf_ZIC PF18366.1 KFQ96244.1 - 0.043 13.9 0.4 3.9 7.7 0.1 2.1 1 1 1 2 2 2 0 Zic proteins zinc finger domain Zn-C2H2_12 PF18112.1 KFQ96244.1 - 0.045 14.2 1.5 0.13 12.7 0.1 2.1 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-ribbon_3 PF13248.6 KFQ96244.1 - 0.046 13.1 3.3 0.3 10.6 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-trcl PF13451.6 KFQ96244.1 - 0.06 13.3 1.4 1.1 9.3 0.1 2.2 2 0 0 2 2 2 0 Probable zinc-ribbon domain Terminase_GpA PF05876.12 KFQ96244.1 - 0.083 11.4 0.8 0.082 11.5 0.8 1.0 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) FYVE PF01363.21 KFQ96244.1 - 0.091 12.9 4.8 0.89 9.7 3.4 2.0 1 1 1 2 2 2 0 FYVE zinc finger Zn_ribbon_recom PF13408.6 KFQ96244.1 - 0.1 13.1 3.8 3 8.4 1.4 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain CxC7 PF18866.1 KFQ96244.1 - 0.11 12.6 1.3 1.9 8.7 0.1 2.0 1 1 1 2 2 2 0 CxC7 like cysteine cluster associated with KDZ transposases Desulfoferrod_N PF06397.12 KFQ96244.1 - 0.15 11.7 4.1 4.6 6.9 0.3 2.2 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain Zn_Tnp_IS1595 PF12760.7 KFQ96244.1 - 0.17 11.9 5.5 0.32 11.0 5.5 1.5 1 1 0 1 1 1 0 Transposase zinc-ribbon domain DUF2072 PF09845.9 KFQ96244.1 - 0.17 12.1 1.6 9 6.6 0.3 2.1 2 0 0 2 2 2 0 Zn-ribbon containing protein zf-AN1 PF01428.16 KFQ96244.1 - 0.17 12.0 7.4 3.7 7.8 2.0 2.4 1 1 1 2 2 2 0 AN1-like Zinc finger Ogr_Delta PF04606.12 KFQ96244.1 - 0.19 11.7 2.4 1.4 8.9 0.2 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger HalOD2 PF18547.1 KFQ96244.1 - 0.19 11.6 1.9 11 6.0 0.1 2.1 1 1 0 2 2 2 0 Halobacterial output domain 2 Rubredoxin_2 PF18073.1 KFQ96244.1 - 0.25 11.1 6.6 3.1 7.6 1.4 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain UPF0547 PF10571.9 KFQ96244.1 - 0.39 10.8 6.6 1.1 9.5 0.3 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-BED PF02892.15 KFQ96244.1 - 0.65 10.1 5.4 2.3 8.3 0.3 2.2 1 1 1 2 2 2 0 BED zinc finger zf-Mss51 PF13824.6 KFQ96244.1 - 0.84 9.8 6.5 6.2 7.0 1.0 2.1 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-ACC PF17848.1 KFQ96244.1 - 1.5 9.0 5.7 2 8.5 0.3 2.2 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain OrfB_Zn_ribbon PF07282.11 KFQ96244.1 - 2 8.4 5.1 9.5 6.2 4.9 1.9 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zinc_ribbon_2 PF13240.6 KFQ96244.1 - 2.2 8.1 9.6 2.4 8.0 1.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-H2C2_5 PF13909.6 KFQ96244.1 - 9.6 6.1 20.1 6 6.7 5.5 3.6 2 2 0 2 2 2 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KFQ96245.1 - 1.7e-34 116.7 19.5 3.3e-10 39.9 0.2 4.1 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ96245.1 - 4.4e-30 102.5 21.1 1.3e-07 31.6 0.2 4.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ96245.1 - 6.9e-19 66.9 20.1 0.00046 20.8 0.2 4.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ96245.1 - 8.3e-13 48.3 4.3 0.058 13.7 0.7 4.1 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFQ96245.1 - 6.8e-12 45.1 18.6 0.0024 17.8 2.0 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf_UBZ PF18439.1 KFQ96245.1 - 5.3e-07 29.1 11.5 0.059 13.0 0.1 4.1 4 0 0 4 4 4 3 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 KFQ96245.1 - 6e-07 29.7 12.1 0.04 14.3 0.0 4.2 4 0 0 4 4 4 1 Zinc-finger of C2H2 type C1_4 PF07975.12 KFQ96245.1 - 2.8e-06 27.4 8.6 0.061 13.6 3.4 3.8 1 1 1 3 3 3 3 TFIIH C1-like domain Zn-ribbon_8 PF09723.10 KFQ96245.1 - 3.6e-06 27.0 14.5 0.00075 19.6 2.4 2.7 2 1 1 3 3 3 2 Zinc ribbon domain Prok-RING_1 PF14446.6 KFQ96245.1 - 4.9e-06 26.4 1.6 1.8 8.6 0.0 4.1 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 Yippee-Mis18 PF03226.14 KFQ96245.1 - 0.00018 21.7 3.8 0.6 10.4 0.3 3.2 3 1 0 3 3 3 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf_ZIC PF18366.1 KFQ96245.1 - 0.00035 20.6 2.2 14 5.9 0.1 4.0 1 1 3 4 4 4 0 Zic proteins zinc finger domain zinc_ribbon_15 PF17032.5 KFQ96245.1 - 0.00037 21.2 7.0 0.16 12.8 0.6 2.1 1 1 1 2 2 2 2 zinc-ribbon family C1_1 PF00130.22 KFQ96245.1 - 0.0029 17.5 11.8 0.43 10.5 3.0 3.7 1 1 3 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2HE PF16278.5 KFQ96245.1 - 0.0041 17.5 16.0 0.49 10.9 1.0 4.0 1 1 3 4 4 4 1 C2HE / C2H2 / C2HC zinc-binding finger zf-AN1 PF01428.16 KFQ96245.1 - 0.0044 17.1 13.5 5.6 7.2 0.1 4.2 4 0 0 4 4 4 0 AN1-like Zinc finger XPA_N PF01286.18 KFQ96245.1 - 0.006 16.6 12.9 0.47 10.6 0.3 3.9 4 0 0 4 4 4 2 XPA protein N-terminal zf-Di19 PF05605.12 KFQ96245.1 - 0.0068 16.7 9.3 0.033 14.5 2.2 2.6 1 1 2 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.7 KFQ96245.1 - 0.0074 16.3 11.9 15 5.7 11.9 2.7 1 1 0 1 1 1 0 Double zinc ribbon zf-trcl PF13451.6 KFQ96245.1 - 0.0084 16.0 9.0 9.3 6.2 0.2 4.1 4 0 0 4 4 4 0 Probable zinc-ribbon domain LIM PF00412.22 KFQ96245.1 - 0.0095 16.1 10.4 0.53 10.6 2.6 3.6 1 1 1 2 2 2 1 LIM domain DUF2256 PF10013.9 KFQ96245.1 - 0.021 14.9 8.6 0.55 10.4 0.1 3.9 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) Zf_RING PF16744.5 KFQ96245.1 - 0.034 14.2 7.3 1.3 9.2 0.0 3.4 1 1 2 3 3 3 0 KIAA1045 RING finger Zn_Tnp_IS1595 PF12760.7 KFQ96245.1 - 0.035 14.1 15.2 1.7 8.7 0.2 4.0 4 0 0 4 4 4 0 Transposase zinc-ribbon domain Evr1_Alr PF04777.13 KFQ96245.1 - 0.037 14.5 10.2 6.7 7.3 0.2 3.8 1 1 3 4 4 4 0 Erv1 / Alr family zf-LYAR PF08790.11 KFQ96245.1 - 0.045 13.7 9.9 14 5.6 0.1 4.2 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger Zn_ribbon_SprT PF17283.2 KFQ96245.1 - 0.089 12.7 13.7 0.89 9.5 3.8 3.3 3 0 0 3 3 3 0 SprT-like zinc ribbon domain CpXC PF14353.6 KFQ96245.1 - 0.11 12.6 8.3 7 6.7 0.0 3.8 2 1 2 4 4 4 0 CpXC protein HypA PF01155.19 KFQ96245.1 - 0.13 12.3 7.4 0.62 10.1 0.6 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DNA_RNApol_7kD PF03604.13 KFQ96245.1 - 0.13 12.0 8.2 11 5.8 0.2 4.0 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit Zn-C2H2_12 PF18112.1 KFQ96245.1 - 0.15 12.6 0.4 0.15 12.6 0.4 3.2 4 0 0 4 4 2 0 Autophagy receptor zinc finger-C2H2 domain zf-MYST PF17772.1 KFQ96245.1 - 0.16 11.6 5.0 0.38 10.4 0.2 3.0 2 2 2 4 4 3 0 MYST family zinc finger domain zinc-ribbons_6 PF07191.12 KFQ96245.1 - 0.17 11.9 11.1 5.8 7.0 2.4 3.3 1 1 1 2 2 2 0 zinc-ribbons zf-C2HC_2 PF13913.6 KFQ96245.1 - 0.22 11.5 17.2 0.28 11.1 0.4 4.2 4 0 0 4 4 4 0 zinc-finger of a C2HC-type DUF3268 PF11672.8 KFQ96245.1 - 0.24 11.8 5.7 12 6.3 0.7 2.9 1 1 2 3 3 3 0 zinc-finger-containing domain zf-C2H2_3rep PF18868.1 KFQ96245.1 - 0.25 12.0 6.6 34 5.1 3.7 3.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf_C2H2_ZHX PF18387.1 KFQ96245.1 - 0.26 11.0 11.8 7.1 6.3 0.1 3.6 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-HIT PF04438.16 KFQ96245.1 - 0.35 10.8 15.2 11 6.0 0.3 4.1 4 0 0 4 4 4 0 HIT zinc finger DUF2072 PF09845.9 KFQ96245.1 - 0.36 11.1 9.2 28 5.0 0.0 3.6 3 1 1 4 4 4 0 Zn-ribbon containing protein zf-ribbon_3 PF13248.6 KFQ96245.1 - 0.94 9.0 12.2 2.1 7.9 0.1 3.5 4 0 0 4 4 3 0 zinc-ribbon domain ADK_lid PF05191.14 KFQ96245.1 - 1.3 9.0 8.6 9.9 6.2 0.3 3.2 2 1 0 2 2 2 0 Adenylate kinase, active site lid C1_2 PF03107.16 KFQ96245.1 - 1.5 9.2 17.0 28 5.1 0.6 4.1 2 2 1 3 3 3 0 C1 domain zf-C2H2_11 PF16622.5 KFQ96245.1 - 1.6 8.6 17.5 0.17 11.7 2.3 4.1 4 1 0 4 4 4 0 zinc-finger C2H2-type zf-RING_5 PF14634.6 KFQ96245.1 - 2.1 8.4 13.4 20 5.2 2.9 3.6 1 1 3 4 4 4 0 zinc-RING finger domain Vps39_2 PF10367.9 KFQ96245.1 - 2.2 8.8 11.7 38 4.8 0.2 3.9 1 1 3 4 4 4 0 Vacuolar sorting protein 39 domain 2 TFIIS_C PF01096.18 KFQ96245.1 - 2.3 8.1 14.2 9.6 6.2 0.1 4.1 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) zf-Paramyx-P PF13008.7 KFQ96245.1 - 2.5 7.6 14.0 3.5 7.2 0.2 3.9 4 0 0 4 4 4 0 Zinc-binding domain of Paramyxoviridae V protein zf-CRD PF17979.1 KFQ96245.1 - 2.7 8.1 10.9 0.98 9.5 3.4 2.6 1 1 2 3 3 3 0 Cysteine rich domain with multizinc binding regions FYDLN_acid PF09538.10 KFQ96245.1 - 3.3 8.4 8.0 47 4.7 1.2 3.5 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) Ribosomal_L37ae PF01780.19 KFQ96245.1 - 3.5 7.8 13.8 7.3 6.8 0.0 3.9 2 1 1 3 3 3 0 Ribosomal L37ae protein family zinc_ribbon_10 PF10058.9 KFQ96245.1 - 3.6 7.4 11.9 7.2 6.4 1.9 3.0 2 2 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein HNH PF01844.23 KFQ96245.1 - 5.5 7.2 10.6 13 6.1 0.0 3.8 4 0 0 4 4 4 0 HNH endonuclease PHD PF00628.29 KFQ96245.1 - 6.8 6.7 13.6 13 5.8 2.8 3.0 2 2 0 2 2 2 0 PHD-finger DUF2757 PF10955.8 KFQ96245.1 - 8.2 6.8 7.8 38 4.6 0.2 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2757) zf-H2C2_2 PF13465.6 KFQ96246.1 - 4e-47 156.6 53.3 8.3e-10 38.7 1.1 6.5 7 0 0 7 7 6 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ96246.1 - 4.2e-47 156.0 54.3 8.6e-08 32.2 3.9 7.0 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ96246.1 - 1.8e-24 84.3 49.4 0.00055 20.6 3.1 7.0 7 0 0 7 7 7 6 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFQ96246.1 - 1.4e-08 34.7 33.3 6.8e-05 22.9 3.1 4.4 2 2 2 5 5 5 4 Zinc ribbon domain zf_UBZ PF18439.1 KFQ96246.1 - 1.5e-08 34.1 27.7 0.045 13.4 0.2 6.2 6 0 0 6 6 6 4 Ubiquitin-Binding Zinc Finger C1_4 PF07975.12 KFQ96246.1 - 1e-07 32.1 28.6 0.29 11.4 6.6 5.5 1 1 5 6 6 6 4 TFIIH C1-like domain zf-C2H2_6 PF13912.6 KFQ96246.1 - 1.7e-07 31.1 44.7 0.078 13.0 0.7 6.4 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFQ96246.1 - 4.5e-06 26.3 25.0 0.11 12.3 0.9 6.3 6 0 0 6 6 6 4 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 KFQ96246.1 - 5.7e-06 27.0 21.4 0.08 13.7 1.5 3.1 2 1 1 3 3 3 3 zinc-ribbon family OSTMP1 PF09777.9 KFQ96246.1 - 1e-05 25.1 11.4 1.7e-05 24.3 11.4 1.3 1 1 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor zf-C2H2_jaz PF12171.8 KFQ96246.1 - 1.1e-05 25.6 30.4 0.78 10.1 0.1 6.2 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding XPA_N PF01286.18 KFQ96246.1 - 2.1e-05 24.5 30.1 0.16 12.0 0.3 6.1 6 0 0 6 6 6 3 XPA protein N-terminal zf-met PF12874.7 KFQ96246.1 - 3.3e-05 24.1 31.4 0.14 12.5 1.7 6.5 4 2 3 8 8 8 3 Zinc-finger of C2H2 type CpXC PF14353.6 KFQ96246.1 - 0.00041 20.4 23.7 1.3 9.1 0.1 5.7 2 2 2 5 5 5 1 CpXC protein DUF3268 PF11672.8 KFQ96246.1 - 0.0024 18.2 18.7 0.097 13.0 0.4 3.8 1 1 4 5 5 5 3 zinc-finger-containing domain Prok-RING_1 PF14446.6 KFQ96246.1 - 0.0033 17.3 24.3 0.19 11.6 1.8 6.0 4 2 1 5 5 5 1 Prokaryotic RING finger family 1 zf-AN1 PF01428.16 KFQ96246.1 - 0.0038 17.4 30.1 1.4 9.2 0.3 6.2 6 0 0 6 6 6 2 AN1-like Zinc finger Zn_Tnp_IS1595 PF12760.7 KFQ96246.1 - 0.0082 16.1 32.9 0.05 13.6 4.7 4.6 3 1 2 5 5 5 2 Transposase zinc-ribbon domain HypA PF01155.19 KFQ96246.1 - 0.015 15.3 23.7 0.056 13.5 1.0 3.7 1 1 4 5 5 5 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_SprT PF17283.2 KFQ96246.1 - 0.021 14.7 30.0 0.094 12.6 2.9 4.4 4 0 0 4 4 4 0 SprT-like zinc ribbon domain zf_C2H2_10 PF18414.1 KFQ96246.1 - 0.027 14.0 0.2 0.027 14.0 0.2 4.5 4 0 0 4 4 4 0 C2H2 type zinc-finger Fer4_10 PF13237.6 KFQ96246.1 - 0.045 13.9 24.5 1.1 9.4 0.2 5.0 3 2 3 6 6 6 0 4Fe-4S dicluster domain zf-trcl PF13451.6 KFQ96246.1 - 0.05 13.5 24.9 2.3 8.2 0.1 5.7 6 0 0 6 6 6 0 Probable zinc-ribbon domain zf-H2C2_5 PF13909.6 KFQ96246.1 - 0.057 13.2 1.0 0.057 13.2 1.0 8.6 8 2 0 8 8 7 0 C2H2-type zinc-finger domain ADK_lid PF05191.14 KFQ96246.1 - 0.059 13.4 1.0 0.059 13.4 1.0 4.6 3 1 0 3 3 3 0 Adenylate kinase, active site lid Zn-C2H2_12 PF18112.1 KFQ96246.1 - 0.12 12.8 0.7 0.12 12.8 0.7 4.2 6 0 0 6 6 3 0 Autophagy receptor zinc finger-C2H2 domain TFIIS_C PF01096.18 KFQ96246.1 - 0.12 12.2 34.4 1.8 8.5 0.6 6.2 6 0 0 6 6 6 0 Transcription factor S-II (TFIIS) zf-HIT PF04438.16 KFQ96246.1 - 0.25 11.3 31.4 2 8.4 0.3 6.1 6 0 0 6 6 6 0 HIT zinc finger DNA_RNApol_7kD PF03604.13 KFQ96246.1 - 0.28 10.9 26.2 8 6.2 0.2 6.1 5 1 1 6 6 6 0 DNA directed RNA polymerase, 7 kDa subunit zinc-ribbons_6 PF07191.12 KFQ96246.1 - 0.63 10.1 29.5 1.8e+04 -14.2 29.5 4.8 1 1 0 1 1 0 0 zinc-ribbons LIM PF00412.22 KFQ96246.1 - 0.68 10.2 29.1 0.74 10.1 2.5 5.1 1 1 3 5 5 5 0 LIM domain CxC7 PF18866.1 KFQ96246.1 - 1.2 9.3 21.5 4 7.7 0.7 5.7 4 1 2 6 6 6 0 CxC7 like cysteine cluster associated with KDZ transposases zf-MYST PF17772.1 KFQ96246.1 - 1.3 8.6 18.4 0.42 10.3 1.2 4.8 2 2 3 5 5 5 0 MYST family zinc finger domain HalOD2 PF18547.1 KFQ96246.1 - 1.4 8.9 16.8 0.23 11.4 0.6 4.5 5 1 0 5 5 5 0 Halobacterial output domain 2 Yippee-Mis18 PF03226.14 KFQ96246.1 - 1.4 9.1 19.6 24 5.2 0.0 5.5 2 1 3 5 5 5 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-RING_7 PF02591.15 KFQ96246.1 - 6.2 7.1 21.9 3.2 8.0 0.1 5.7 6 0 0 6 6 6 0 C4-type zinc ribbon domain zf-ribbon_3 PF13248.6 KFQ96246.1 - 6.9 6.2 24.5 2.8 7.5 0.1 5.8 6 0 0 6 6 6 0 zinc-ribbon domain PRY PF13765.6 KFQ96247.1 - 6.4e-20 70.5 0.3 9.6e-20 70.0 0.3 1.3 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.28 KFQ96247.1 - 2.1e-08 34.3 0.0 2.9e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 SPRY domain Opiods_neuropep PF01160.18 KFQ96247.1 - 0.093 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide PRY PF13765.6 KFQ96248.1 - 4.6e-22 77.4 0.0 7.2e-22 76.8 0.0 1.3 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.28 KFQ96248.1 - 3.1e-08 33.7 0.0 3.9e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 SPRY domain WD40 PF00400.32 KFQ96249.1 - 6.1e-45 150.3 24.3 6.5e-09 36.3 0.2 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ96249.1 - 8.1e-11 42.1 0.6 0.0029 17.9 0.0 4.6 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFQ96249.1 - 1.2e-05 25.3 0.2 0.0035 17.2 0.0 2.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFQ96249.1 - 5e-05 22.4 0.1 0.63 9.0 0.0 4.0 2 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFQ96249.1 - 0.00013 20.8 4.5 0.11 11.2 0.1 4.0 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KFQ96249.1 - 0.0042 15.7 0.0 0.021 13.3 0.0 1.9 1 1 1 2 2 2 1 Cytochrome D1 heme domain WD40_like PF17005.5 KFQ96249.1 - 0.0057 16.0 0.0 2.3 7.5 0.0 2.1 2 0 0 2 2 2 2 WD40-like domain DUF1416 PF07210.12 KFQ96249.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) PD40 PF07676.12 KFQ96249.1 - 0.19 11.7 3.6 15 5.6 0.0 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PRY PF13765.6 KFQ96250.1 - 2.1e-24 84.9 0.5 9.8e-24 82.7 0.3 2.0 2 0 0 2 2 2 1 SPRY-associated domain SPRY PF00622.28 KFQ96250.1 - 8.3e-16 58.2 0.1 1e-15 57.9 0.1 1.1 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_4 PF15227.6 KFQ96251.1 - 8.1e-16 57.9 10.8 8.1e-16 57.9 10.8 2.2 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.24 KFQ96251.1 - 2.1e-11 43.8 1.9 2.1e-11 43.8 1.9 3.5 4 0 0 4 4 4 1 B-box zinc finger zf-RING_UBOX PF13445.6 KFQ96251.1 - 2.5e-11 43.4 8.4 2.5e-11 43.4 8.4 1.8 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFQ96251.1 - 3.5e-10 39.6 10.0 3.5e-10 39.6 10.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFQ96251.1 - 9.2e-10 38.2 9.5 9.2e-10 38.2 9.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ96251.1 - 1e-08 35.3 11.0 1e-08 35.3 11.0 2.3 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFQ96251.1 - 1.2e-07 31.5 8.7 1.2e-07 31.5 8.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFQ96251.1 - 1.1e-06 28.5 10.0 1.1e-06 28.5 10.0 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 KFQ96251.1 - 7e-06 25.8 4.6 1.4e-05 24.8 4.6 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KFQ96251.1 - 1e-05 25.6 3.6 1e-05 25.6 3.6 2.2 2 0 0 2 2 2 1 zinc RING finger of MSL2 U-box PF04564.15 KFQ96251.1 - 0.0054 16.9 0.0 0.0095 16.1 0.0 1.4 1 0 0 1 1 1 1 U-box domain Prok-RING_4 PF14447.6 KFQ96251.1 - 0.0065 16.3 9.2 0.0065 16.3 9.2 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 RDM PF11002.8 KFQ96251.1 - 0.037 14.0 0.0 0.054 13.5 0.0 1.2 1 0 0 1 1 1 0 RFPL defining motif (RDM) IBR PF01485.21 KFQ96251.1 - 0.55 10.5 16.5 0.094 13.0 2.1 2.9 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-rbx1 PF12678.7 KFQ96251.1 - 4 7.8 16.0 1.4 9.3 9.4 2.8 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFQ96251.1 - 4.8 7.3 9.2 0.74 9.9 4.6 2.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KFQ96251.1 - 5.1 6.9 14.2 0.08 12.7 6.2 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_4 PF14570.6 KFQ96251.1 - 8.2 6.3 19.8 1.1 9.2 12.3 3.0 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain PRY PF13765.6 KFQ96252.1 - 2.6e-24 84.6 0.4 5.4e-24 83.6 0.4 1.6 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.28 KFQ96252.1 - 3.4e-11 43.3 0.1 4.4e-11 43.0 0.1 1.1 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_4 PF15227.6 KFQ96253.1 - 7.8e-15 54.7 12.2 7.8e-15 54.7 12.2 2.1 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.24 KFQ96253.1 - 9.2e-12 44.9 2.9 9.2e-12 44.9 2.9 3.5 2 1 1 3 3 3 1 B-box zinc finger zf-C3HC4 PF00097.25 KFQ96253.1 - 4e-10 39.4 11.8 4e-10 39.4 11.8 1.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFQ96253.1 - 1.2e-09 38.0 10.7 1.2e-09 38.0 10.7 1.9 2 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFQ96253.1 - 7.3e-09 35.3 11.9 7.3e-09 35.3 11.9 1.9 2 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFQ96253.1 - 8.1e-08 32.0 9.5 8.1e-08 32.0 9.5 2.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ96253.1 - 2.9e-07 30.7 13.2 2.9e-07 30.7 13.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KFQ96253.1 - 5.2e-05 23.1 12.8 5.2e-05 23.1 12.8 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_10 PF16685.5 KFQ96253.1 - 0.00059 19.9 4.5 0.00059 19.9 4.5 2.4 2 1 0 2 2 2 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 KFQ96253.1 - 0.0074 16.1 15.5 0.0099 15.7 9.9 3.0 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 KFQ96253.1 - 0.024 14.6 8.0 0.03 14.3 4.3 2.1 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.6 KFQ96253.1 - 0.036 13.9 7.9 0.078 12.9 7.9 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein U-box PF04564.15 KFQ96253.1 - 0.084 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 U-box domain zf-RING_4 PF14570.6 KFQ96253.1 - 1 9.2 17.9 0.17 11.7 12.5 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KFQ96253.1 - 1.7 8.7 12.3 0.32 11.1 7.7 2.1 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger PRY PF13765.6 KFQ96254.1 - 1.6e-23 82.1 0.1 2.4e-23 81.5 0.1 1.3 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.28 KFQ96254.1 - 1.6e-06 28.2 0.0 1.9e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 SPRY domain Opiods_neuropep PF01160.18 KFQ96254.1 - 0.002 18.1 0.0 0.0033 17.5 0.0 1.2 1 0 0 1 1 1 1 Vertebrate endogenous opioids neuropeptide PRY PF13765.6 KFQ96255.1 - 1.9e-26 91.4 0.1 3.2e-26 90.7 0.1 1.4 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.28 KFQ96255.1 - 5.8e-12 45.8 0.0 7.5e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 SPRY domain PRY PF13765.6 KFQ96256.1 - 2.1e-13 49.7 0.0 4.4e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.28 KFQ96256.1 - 1.2e-10 41.6 0.0 1.5e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 SPRY domain PRY PF13765.6 KFQ96257.1 - 7.9e-26 89.4 0.6 1.2e-25 88.9 0.6 1.3 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.28 KFQ96257.1 - 1.1e-12 48.1 0.0 1.3e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 SPRY domain Opiods_neuropep PF01160.18 KFQ96257.1 - 0.011 15.9 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide DUF4723 PF15851.5 KFQ96258.1 - 0.0044 17.1 1.6 0.006 16.7 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4723) DUF4497 PF14924.6 KFQ96258.1 - 0.053 14.0 0.0 0.061 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4497) PRY PF13765.6 KFQ96259.1 - 1.1e-19 69.8 0.3 1.6e-18 66.1 0.1 2.2 2 0 0 2 2 2 1 SPRY-associated domain SPRY PF00622.28 KFQ96259.1 - 1e-15 57.9 0.4 1.4e-15 57.4 0.4 1.2 1 0 0 1 1 1 1 SPRY domain Neuralized PF07177.12 KFQ96259.1 - 0.0095 15.9 0.0 0.011 15.7 0.0 1.3 1 1 0 1 1 1 1 Neuralized Amino_oxidase PF01593.24 KFQ96260.1 - 5.4e-73 246.8 0.0 6.3e-73 246.6 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFQ96260.1 - 1.4e-15 57.2 0.0 3.6e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KFQ96260.1 - 7.2e-07 28.7 0.1 2.4e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KFQ96260.1 - 1.1e-05 25.2 0.0 0.00011 21.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFQ96260.1 - 1.3e-05 25.6 0.1 6.8e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFQ96260.1 - 2.1e-05 23.8 0.1 3.7e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFQ96260.1 - 2.7e-05 23.6 0.0 5.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFQ96260.1 - 5.7e-05 22.0 0.8 0.00015 20.6 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KFQ96260.1 - 6.6e-05 22.3 0.2 0.00011 21.5 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KFQ96260.1 - 0.00011 21.6 0.2 0.00053 19.3 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KFQ96260.1 - 0.00011 21.7 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KFQ96260.1 - 0.015 14.5 0.1 0.042 13.1 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KFQ96260.1 - 0.018 13.8 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 MCRA family 3HCDH_N PF02737.18 KFQ96260.1 - 0.035 14.0 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.19 KFQ96260.1 - 0.037 12.5 0.0 0.081 11.3 0.0 1.5 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like GIDA PF01134.22 KFQ96260.1 - 0.038 13.1 0.0 0.069 12.2 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 KFQ96260.1 - 0.046 12.6 0.5 0.084 11.7 0.5 1.4 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.18 KFQ96260.1 - 0.077 13.3 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 KFQ96260.1 - 0.17 11.5 0.5 0.56 9.9 0.1 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 KFQ96260.1 - 0.18 10.8 0.1 0.4 9.7 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein zf-H2C2_2 PF13465.6 KFQ96261.1 - 1.7e-91 296.9 73.8 3.2e-10 39.9 1.3 12.2 12 0 0 12 12 12 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ96261.1 - 4.4e-80 259.9 84.1 6e-07 29.6 0.3 12.1 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ96261.1 - 2.4e-46 152.4 77.9 0.00051 20.6 1.1 12.1 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ96261.1 - 7.6e-22 77.1 20.5 0.03 14.6 0.5 11.8 12 0 0 12 12 12 4 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KFQ96261.1 - 9.5e-20 70.4 49.8 0.00093 19.3 0.9 8.9 5 3 5 10 10 10 8 Zinc ribbon domain zf_UBZ PF18439.1 KFQ96261.1 - 2.7e-19 68.4 37.1 0.14 11.7 0.1 12.1 12 0 0 12 12 12 7 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 KFQ96261.1 - 3.7e-17 61.9 76.9 0.00018 21.4 0.2 12.9 13 1 0 13 13 12 7 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFQ96261.1 - 4.5e-12 45.5 55.7 0.22 11.3 0.2 12.1 12 0 0 12 12 12 5 zinc-finger C2H2-type DZR PF12773.7 KFQ96261.1 - 5.4e-10 39.1 43.3 0.067 13.2 4.8 6.8 2 2 3 5 5 5 2 Double zinc ribbon zf-LYAR PF08790.11 KFQ96261.1 - 7.3e-09 35.4 44.5 0.13 12.2 0.1 11.2 12 0 0 12 12 12 4 LYAR-type C2HC zinc finger CpXC PF14353.6 KFQ96261.1 - 1.7e-08 34.5 36.8 3.4 7.7 0.1 11.1 3 3 9 12 12 12 2 CpXC protein zinc_ribbon_15 PF17032.5 KFQ96261.1 - 1.9e-08 35.0 34.1 0.18 12.6 0.4 6.6 1 1 4 5 5 5 3 zinc-ribbon family zf-met PF12874.7 KFQ96261.1 - 3e-08 33.8 47.7 0.49 10.9 1.3 11.8 12 0 0 12 12 12 2 Zinc-finger of C2H2 type C1_4 PF07975.12 KFQ96261.1 - 3.4e-07 30.4 35.9 0.16 12.2 0.3 8.6 1 1 6 9 9 9 3 TFIIH C1-like domain XPA_N PF01286.18 KFQ96261.1 - 3.5e-07 30.2 43.9 0.093 12.8 0.2 11.1 12 0 0 12 12 12 1 XPA protein N-terminal Zn_ribbon_SprT PF17283.2 KFQ96261.1 - 3.5e-07 30.0 62.3 0.0015 18.4 1.5 9.5 6 2 2 8 8 8 2 SprT-like zinc ribbon domain zf-Di19 PF05605.12 KFQ96261.1 - 6.3e-07 29.6 41.7 0.058 13.7 0.3 7.8 3 2 5 9 9 9 4 Drought induced 19 protein (Di19), zinc-binding DNA_RNApol_7kD PF03604.13 KFQ96261.1 - 7.3e-07 28.8 48.7 3.3 7.5 0.1 12.0 12 0 0 12 12 12 1 DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_3rep PF18868.1 KFQ96261.1 - 1.2e-06 29.2 25.4 1.5 9.5 0.5 7.4 3 2 2 5 5 5 3 Zinc finger C2H2-type, 3 repeats zf-trcl PF13451.6 KFQ96261.1 - 2.3e-06 27.4 49.6 2.9 7.9 0.1 11.6 10 2 0 10 10 10 3 Probable zinc-ribbon domain FYDLN_acid PF09538.10 KFQ96261.1 - 4e-06 27.5 27.1 16 6.2 0.2 10.5 1 1 9 10 10 10 0 Protein of unknown function (FYDLN_acid) HypA PF01155.19 KFQ96261.1 - 5.2e-06 26.4 34.1 0.88 9.6 2.3 6.8 1 1 3 4 4 4 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ADK_lid PF05191.14 KFQ96261.1 - 0.00016 21.6 49.4 0.083 12.9 4.4 9.0 4 2 6 10 10 10 2 Adenylate kinase, active site lid zinc_ribbon_4 PF13717.6 KFQ96261.1 - 0.00016 21.5 43.8 1.3 9.0 0.1 10.8 8 4 1 9 9 9 2 zinc-ribbon domain DUF3268 PF11672.8 KFQ96261.1 - 0.00034 20.9 36.0 1 9.7 1.1 6.7 1 1 8 10 10 10 4 zinc-finger-containing domain Zn_ribbon_recom PF13408.6 KFQ96261.1 - 0.0027 18.2 65.3 3.4 8.2 1.8 10.5 2 2 8 10 10 10 1 Recombinase zinc beta ribbon domain zf-AN1 PF01428.16 KFQ96261.1 - 0.02 15.0 59.0 13 6.1 0.2 12.1 10 2 2 12 12 12 0 AN1-like Zinc finger IBR PF01485.21 KFQ96261.1 - 0.045 14.0 46.4 0.14 12.4 1.3 6.9 1 1 2 3 3 2 0 IBR domain, a half RING-finger domain YhfH PF14149.6 KFQ96261.1 - 0.078 13.0 50.0 9.8 6.2 0.1 11.4 12 0 0 12 12 12 0 YhfH-like protein BolA PF01722.18 KFQ96261.1 - 0.078 13.3 0.1 0.078 13.3 0.1 4.8 5 0 0 5 5 5 0 BolA-like protein zinc-ribbons_6 PF07191.12 KFQ96261.1 - 0.11 12.4 39.6 3.9 7.5 0.2 8.1 2 1 1 3 3 2 0 zinc-ribbons Elf1 PF05129.13 KFQ96261.1 - 0.15 12.1 35.2 0.16 12.1 0.3 7.4 1 1 9 10 10 10 0 Transcription elongation factor Elf1 like TFIIS_C PF01096.18 KFQ96261.1 - 0.22 11.4 53.5 9.5 6.2 0.2 11.5 11 1 0 11 11 11 0 Transcription factor S-II (TFIIS) zinc_ribbon_9 PF14369.6 KFQ96261.1 - 0.35 11.2 51.3 6.5 7.1 0.5 10.6 10 1 2 12 12 11 0 zinc-ribbon Zn_Tnp_IS1595 PF12760.7 KFQ96261.1 - 0.39 10.7 67.5 0.41 10.7 2.6 7.6 5 2 4 9 9 9 0 Transposase zinc-ribbon domain LIM PF00412.22 KFQ96261.1 - 0.59 10.4 38.0 4.2 7.7 3.3 8.3 1 1 10 11 11 11 0 LIM domain zinc_ribbon_5 PF13719.6 KFQ96261.1 - 3.1 7.6 46.0 9.3 6.1 0.1 10.7 10 2 1 11 11 11 0 zinc-ribbon domain Collagen_mid PF15984.5 KFQ96262.1 - 0.018 14.8 9.3 0.029 14.1 9.3 1.4 1 1 0 1 1 1 0 Bacterial collagen, middle region zf-C2H2 PF00096.26 KFQ96263.1 - 5.1e-13 48.7 3.4 5.2e-06 26.6 1.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ96263.1 - 1.3e-08 34.9 11.6 0.0015 18.9 0.2 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ96263.1 - 2.8e-05 24.6 4.8 0.11 13.4 1.9 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFQ96263.1 - 0.00014 21.5 1.4 0.078 12.8 0.2 2.1 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-trcl PF13451.6 KFQ96263.1 - 0.00018 21.3 1.5 0.014 15.2 0.1 2.1 2 0 0 2 2 2 1 Probable zinc-ribbon domain zf-LYAR PF08790.11 KFQ96263.1 - 0.00029 20.7 0.1 0.27 11.2 0.0 2.3 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 KFQ96263.1 - 0.0027 17.3 0.2 0.96 9.1 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger Zn_ribbon_recom PF13408.6 KFQ96263.1 - 0.0045 17.5 3.3 1.5 9.4 0.3 2.1 2 0 0 2 2 2 2 Recombinase zinc beta ribbon domain XPA_N PF01286.18 KFQ96263.1 - 0.011 15.7 0.6 4 7.6 0.1 2.1 2 0 0 2 2 2 0 XPA protein N-terminal DUF2321 PF10083.9 KFQ96263.1 - 0.016 14.9 0.1 0.017 14.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) DNA_RNApol_7kD PF03604.13 KFQ96263.1 - 0.022 14.4 2.6 3.4 7.4 0.4 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Ribosomal_L34e PF01199.18 KFQ96263.1 - 0.039 14.2 2.9 2.7 8.4 0.1 2.1 1 1 1 2 2 2 0 Ribosomal protein L34e Zn-ribbon_8 PF09723.10 KFQ96263.1 - 0.045 13.9 3.2 0.22 11.7 3.5 1.8 1 1 1 2 2 2 0 Zinc ribbon domain zf-met PF12874.7 KFQ96263.1 - 0.068 13.6 1.8 1.1 9.7 0.0 2.7 2 1 0 2 2 2 0 Zinc-finger of C2H2 type DUF2072 PF09845.9 KFQ96263.1 - 0.12 12.7 3.3 2.3 8.5 0.2 2.1 2 0 0 2 2 2 0 Zn-ribbon containing protein HypA PF01155.19 KFQ96263.1 - 0.14 12.2 0.4 0.15 12.1 0.4 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-CHCC PF10276.9 KFQ96263.1 - 0.31 11.1 4.5 3.6 7.7 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger domain Ribosomal_L37ae PF01780.19 KFQ96263.1 - 0.6 10.2 4.1 2.4 8.3 0.5 2.1 1 1 1 2 2 2 0 Ribosomal L37ae protein family HalOD2 PF18547.1 KFQ96263.1 - 1.4 8.9 8.1 7.1 6.6 0.8 2.3 1 1 0 1 1 1 0 Halobacterial output domain 2 TFIIS_C PF01096.18 KFQ96263.1 - 1.4 8.8 4.4 11 5.9 0.4 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) YhfH PF14149.6 KFQ96263.1 - 1.8 8.6 5.2 14 5.8 0.3 2.1 2 0 0 2 2 2 0 YhfH-like protein zf-C2H2_6 PF13912.6 KFQ96263.1 - 2.4 8.3 12.3 15 5.8 0.9 3.2 2 2 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFQ96264.1 - 4.3e-45 150.2 60.0 8.1e-11 41.8 0.9 8.0 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ96264.1 - 3.7e-34 115.3 55.1 3.8e-07 30.2 1.4 8.2 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ96264.1 - 9.8e-19 66.4 54.6 0.00084 20.0 1.4 8.2 8 0 0 8 8 8 5 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFQ96264.1 - 1e-05 25.5 34.1 0.0054 16.8 3.5 5.5 2 1 4 6 6 6 4 Zinc ribbon domain zf-LYAR PF08790.11 KFQ96264.1 - 1.3e-05 24.9 16.7 9.1 6.3 0.0 7.2 7 0 0 7 7 7 0 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 KFQ96264.1 - 1.7e-05 24.3 23.7 0.52 10.0 0.1 7.2 7 0 0 7 7 7 2 Ubiquitin-Binding Zinc Finger zf-trcl PF13451.6 KFQ96264.1 - 6.4e-05 22.8 29.5 0.23 11.4 0.4 7.0 6 1 0 6 6 6 3 Probable zinc-ribbon domain zf-C2H2_11 PF16622.5 KFQ96264.1 - 9.4e-05 22.1 45.6 0.052 13.3 0.5 7.5 8 0 0 8 8 8 5 zinc-finger C2H2-type ADK_lid PF05191.14 KFQ96264.1 - 0.00031 20.7 14.5 0.68 10.0 1.0 4.9 3 2 0 3 3 3 3 Adenylate kinase, active site lid XPA_N PF01286.18 KFQ96264.1 - 0.00085 19.3 25.0 3.9 7.6 0.2 7.1 7 0 0 7 7 7 1 XPA protein N-terminal zf-C2H2_jaz PF12171.8 KFQ96264.1 - 0.0014 18.9 19.6 2.6 8.5 0.1 6.6 7 0 0 7 7 6 2 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFQ96264.1 - 0.0018 18.0 3.9 0.19 11.6 1.0 2.9 2 0 0 2 2 2 1 GAGA factor zinc_ribbon_15 PF17032.5 KFQ96264.1 - 0.004 17.9 20.0 0.57 11.0 0.5 4.1 2 2 1 4 4 4 3 zinc-ribbon family zf-C2H2_6 PF13912.6 KFQ96264.1 - 0.023 14.7 2.3 0.023 14.7 2.3 9.4 8 3 0 8 8 8 0 C2H2-type zinc finger FYDLN_acid PF09538.10 KFQ96264.1 - 0.051 14.2 15.8 4.4 8.0 0.1 5.5 1 1 5 6 6 6 0 Protein of unknown function (FYDLN_acid) DUF3268 PF11672.8 KFQ96264.1 - 0.06 13.7 12.4 1 9.7 0.5 3.6 3 1 1 4 4 4 0 zinc-finger-containing domain HypA PF01155.19 KFQ96264.1 - 0.22 11.6 22.9 0.65 10.0 0.9 4.2 1 1 4 5 5 5 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_9 PF14369.6 KFQ96264.1 - 0.3 11.4 31.4 7 7.0 0.2 6.4 6 1 0 6 6 6 0 zinc-ribbon C1_4 PF07975.12 KFQ96264.1 - 0.31 11.3 26.3 0.8 10.0 0.3 5.4 2 2 4 6 6 5 0 TFIIH C1-like domain CpXC PF14353.6 KFQ96264.1 - 0.33 11.0 23.7 16 5.5 0.1 6.5 3 2 2 6 6 6 0 CpXC protein YhfH PF14149.6 KFQ96264.1 - 0.72 9.9 31.0 4.6 7.3 0.2 7.0 7 0 0 7 7 7 0 YhfH-like protein BolA PF01722.18 KFQ96264.1 - 1.3 9.4 12.8 18 5.7 0.4 4.1 3 1 1 4 4 4 0 BolA-like protein DUF2039 PF10217.9 KFQ96264.1 - 2.2 8.7 19.4 1.6 9.1 0.2 3.6 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2039) Zn_ribbon_recom PF13408.6 KFQ96264.1 - 2.6 8.6 33.8 5.9 7.5 4.5 5.7 2 2 2 5 5 5 0 Recombinase zinc beta ribbon domain LIM PF00412.22 KFQ96264.1 - 2.9 8.2 22.3 20 5.5 1.3 5.6 1 1 5 6 6 6 0 LIM domain zf-H2C2_2 PF13465.6 KFQ96265.1 - 6e-75 244.6 88.7 1.9e-08 34.4 1.3 13.0 13 1 0 13 13 12 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ96265.1 - 2.7e-70 229.1 86.1 2.3e-06 27.8 2.1 12.1 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ96265.1 - 1.5e-39 131.2 85.1 9.1e-05 23.0 0.1 12.1 12 0 0 12 12 12 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ96265.1 - 1.3e-19 70.0 20.5 0.026 14.8 0.0 11.7 12 0 0 12 12 12 5 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFQ96265.1 - 1.6e-19 69.3 66.3 0.0019 17.9 0.3 12.2 12 0 0 12 12 12 7 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KFQ96265.1 - 9.1e-12 44.9 52.9 0.0024 17.9 1.1 8.4 6 3 2 8 8 8 3 Zinc ribbon domain zf_UBZ PF18439.1 KFQ96265.1 - 2.5e-10 39.7 46.3 0.12 12.0 0.0 11.9 12 0 0 12 12 12 5 Ubiquitin-Binding Zinc Finger C1_4 PF07975.12 KFQ96265.1 - 2.4e-06 27.6 30.4 1.7 9.0 2.1 8.2 3 3 4 8 8 8 3 TFIIH C1-like domain DZR PF12773.7 KFQ96265.1 - 4.1e-05 23.5 47.5 0.024 14.7 3.1 6.8 2 1 1 3 3 2 2 Double zinc ribbon ADK_lid PF05191.14 KFQ96265.1 - 5.8e-05 23.0 32.5 0.15 12.0 0.2 8.0 4 2 4 8 8 8 4 Adenylate kinase, active site lid Zn_ribbon_SprT PF17283.2 KFQ96265.1 - 9.3e-05 22.3 59.2 0.11 12.4 3.6 9.3 5 3 3 8 8 8 4 SprT-like zinc ribbon domain HypA PF01155.19 KFQ96265.1 - 0.00012 22.1 29.6 0.21 11.6 0.3 6.3 2 2 3 5 5 5 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA BolA PF01722.18 KFQ96265.1 - 0.00056 20.1 7.7 4.5 7.6 1.2 4.8 4 1 0 4 4 4 1 BolA-like protein zf-C2HC_2 PF13913.6 KFQ96265.1 - 0.00079 19.3 0.2 0.00079 19.3 0.2 11.6 12 0 0 12 12 11 3 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 KFQ96265.1 - 0.0022 18.7 26.9 2.3 9.0 0.1 6.2 2 2 5 8 8 8 2 zinc-ribbon family zf-C2H2_6 PF13912.6 KFQ96265.1 - 0.0022 18.0 0.4 0.0022 18.0 0.4 12.7 12 3 0 12 12 11 4 C2H2-type zinc finger FYDLN_acid PF09538.10 KFQ96265.1 - 0.0067 17.1 26.2 20 5.9 1.2 9.4 2 2 6 9 9 9 0 Protein of unknown function (FYDLN_acid) DUF3268 PF11672.8 KFQ96265.1 - 0.011 16.1 0.4 0.011 16.1 0.4 5.6 1 1 5 7 7 7 0 zinc-finger-containing domain CpXC PF14353.6 KFQ96265.1 - 0.017 15.1 36.1 0.34 10.9 0.0 9.3 6 2 4 10 10 10 0 CpXC protein IBD PF10416.9 KFQ96265.1 - 0.061 13.4 0.4 85 3.2 0.0 4.0 4 0 0 4 4 4 0 Transcription-initiator DNA-binding domain IBD XPA_N PF01286.18 KFQ96265.1 - 0.073 13.1 47.0 5.8 7.0 0.0 11.4 12 0 0 12 12 12 0 XPA protein N-terminal BHD_1 PF10403.9 KFQ96265.1 - 0.1 12.5 0.1 10 6.0 0.0 3.4 3 0 0 3 3 3 0 Rad4 beta-hairpin domain 1 zf-Di19 PF05605.12 KFQ96265.1 - 0.11 12.8 0.5 0.11 12.8 0.5 7.4 3 2 5 9 9 9 0 Drought induced 19 protein (Di19), zinc-binding Elf1 PF05129.13 KFQ96265.1 - 0.11 12.5 0.1 0.11 12.5 0.1 6.9 1 1 7 8 8 8 0 Transcription elongation factor Elf1 like zf-met PF12874.7 KFQ96265.1 - 4.6 7.8 52.1 4.4 7.8 0.0 11.2 12 0 0 12 12 12 0 Zinc-finger of C2H2 type DUF2256 PF10013.9 KFQ96265.1 - 6 7.1 45.9 2.8 8.1 0.0 10.9 12 0 0 12 12 12 0 Uncharacterized protein conserved in bacteria (DUF2256) KRAB PF01352.27 KFQ96266.1 - 2.9e-10 39.6 0.1 3.7e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 KRAB box RyR PF02026.16 KFQ96266.1 - 0.025 14.7 0.0 0.029 14.5 0.0 1.0 1 0 0 1 1 1 0 RyR domain PRY PF13765.6 KFQ96267.1 - 8e-22 76.6 0.1 1.4e-21 75.9 0.1 1.4 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.28 KFQ96267.1 - 2.9e-16 59.6 0.1 3.8e-16 59.3 0.1 1.1 1 0 0 1 1 1 1 SPRY domain zf-C2H2 PF00096.26 KFQ96268.1 - 4.8e-19 67.7 35.2 0.0002 21.6 0.6 5.5 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ96268.1 - 1e-12 47.8 27.2 4.6e-05 23.6 0.3 5.0 3 1 1 4 4 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ96268.1 - 6.3e-11 42.2 33.1 0.015 16.1 0.4 5.6 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFQ96268.1 - 4.3e-06 26.9 7.7 4.3e-06 26.9 7.7 2.5 1 1 2 3 3 3 2 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 KFQ96268.1 - 0.0043 17.0 0.4 0.0043 17.0 0.4 6.0 5 1 0 5 5 5 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFQ96268.1 - 0.037 14.1 13.9 0.26 11.4 0.2 3.9 3 1 1 4 4 4 0 Zinc ribbon domain zf-C2H2_7 PF15269.6 KFQ96268.1 - 0.068 13.3 0.2 0.068 13.3 0.2 2.7 2 1 0 2 2 2 0 Zinc-finger zf-C2H2_jaz PF12171.8 KFQ96268.1 - 0.45 10.9 0.1 0.45 10.9 0.1 4.6 5 0 0 5 5 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFQ96268.1 - 1.2 9.7 23.1 9.5 6.8 0.1 5.3 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-LYAR PF08790.11 KFQ96268.1 - 6.7 6.7 12.3 8.6 6.4 0.9 3.8 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zinc_ribbon_15 PF17032.5 KFQ96268.1 - 7.9 7.3 13.9 12 6.8 2.4 2.8 1 1 1 2 2 2 0 zinc-ribbon family DUF1906 PF08924.11 KFQ96269.1 - 0.021 15.0 0.0 0.022 14.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1906) Lectin_C PF00059.21 KFQ96269.1 - 0.023 15.4 0.4 0.031 15.0 0.1 1.4 1 1 0 1 1 1 0 Lectin C-type domain Lectin_C PF00059.21 KFQ96270.1 - 3.5e-11 43.8 5.4 4.3e-11 43.5 5.4 1.1 1 0 0 1 1 1 1 Lectin C-type domain CBM_11 PF03425.13 KFQ96270.1 - 0.029 14.2 2.4 0.032 14.1 2.4 1.0 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) Josephin PF02099.17 KFQ96270.1 - 0.14 12.3 3.7 1.4 9.0 0.9 2.1 2 0 0 2 2 2 0 Josephin UL45 PF05473.12 KFQ96271.1 - 0.0016 18.1 2.8 0.0024 17.6 2.8 1.3 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 KFQ96272.1 - 5.9e-13 49.5 0.7 1.1e-12 48.6 0.7 1.5 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 KFQ96272.1 - 0.0013 18.4 0.5 0.002 17.8 0.5 1.4 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Toxin_13 PF07822.11 KFQ96272.1 - 0.087 13.0 0.7 0.27 11.4 0.7 1.8 1 1 0 1 1 1 0 Neurotoxin B-IV-like protein SLC3A2_N PF16028.5 KFQ96272.1 - 0.13 11.9 0.3 0.28 10.8 0.3 1.5 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus PRY PF13765.6 KFQ96273.1 - 7.4e-17 60.7 0.0 1.2e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.28 KFQ96273.1 - 6.7e-13 48.8 0.2 8.3e-13 48.5 0.2 1.1 1 0 0 1 1 1 1 SPRY domain GNT-I PF03071.15 KFQ96274.1 - 1.1e-173 578.0 0.1 1.2e-173 577.8 0.1 1.0 1 0 0 1 1 1 1 GNT-I family Glyco_tranf_2_3 PF13641.6 KFQ96274.1 - 2.9e-05 24.1 0.6 0.0005 20.0 0.4 2.9 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KFQ96274.1 - 0.036 13.9 0.1 0.2 11.4 0.1 2.0 1 1 0 1 1 1 0 Glycosyl transferase family 2 PRY PF13765.6 KFQ96275.1 - 1.5e-22 79.0 0.9 2.3e-22 78.3 0.4 1.6 2 0 0 2 2 2 1 SPRY-associated domain SPRY PF00622.28 KFQ96275.1 - 2.6e-14 53.4 0.1 4.1e-14 52.7 0.0 1.3 2 0 0 2 2 2 1 SPRY domain DUF4988 PF16378.5 KFQ96275.1 - 0.03 14.0 0.2 0.04 13.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function Ank_5 PF13857.6 KFQ96276.1 - 8.1e-09 35.6 0.2 9.5e-09 35.4 0.2 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KFQ96276.1 - 3.2e-07 30.5 0.7 1.8e-05 24.9 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 KFQ96276.1 - 6.6e-07 29.8 0.0 8.9e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFQ96276.1 - 3.9e-05 23.7 0.2 0.00047 20.4 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KFQ96276.1 - 0.00027 21.4 0.1 0.00038 20.9 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) AAA_2 PF07724.14 KFQ96277.1 - 1.5e-45 155.4 0.5 2.8e-45 154.5 0.5 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KFQ96277.1 - 7.8e-10 38.9 0.0 2.9e-09 37.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 KFQ96277.1 - 8.8e-10 38.5 0.0 3.8e-09 36.5 0.0 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KFQ96277.1 - 2.2e-08 34.6 0.0 2.1e-07 31.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFQ96277.1 - 3.8e-05 23.4 0.1 6.7e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 KFQ96277.1 - 0.00016 21.0 0.0 0.00052 19.4 0.0 1.9 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 KFQ96277.1 - 0.00022 21.6 0.1 0.022 15.2 0.0 2.9 3 1 0 3 3 3 1 AAA ATPase domain YchF-GTPase_C PF06071.13 KFQ96277.1 - 0.00091 19.4 0.0 0.0028 17.8 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) Torsin PF06309.11 KFQ96277.1 - 0.0027 17.8 0.0 0.008 16.3 0.0 1.9 2 0 0 2 2 2 1 Torsin AAA_24 PF13479.6 KFQ96277.1 - 0.0046 16.7 0.0 0.0091 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KFQ96277.1 - 0.0053 16.6 0.0 0.073 12.9 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFQ96277.1 - 0.014 15.7 0.0 0.052 13.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFQ96277.1 - 0.024 15.2 0.2 0.21 12.1 0.2 2.4 1 1 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 KFQ96277.1 - 0.035 14.0 0.2 0.1 12.5 0.2 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KFQ96277.1 - 0.093 12.9 1.0 0.85 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Exo_endo_phos PF03372.23 KFQ96278.1 - 2.9e-10 40.1 0.0 6.1e-10 39.0 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FlpD PF02662.16 KFQ96278.1 - 0.084 12.9 0.1 0.28 11.2 0.0 1.8 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit KAsynt_C_assoc PF16197.5 KFQ96278.1 - 0.25 11.8 1.7 4.7 7.7 0.0 3.0 3 0 0 3 3 3 0 Ketoacyl-synthetase C-terminal extension Folate_rec PF03024.14 KFQ96279.1 - 6.6e-41 140.0 19.6 7.2e-41 139.9 19.6 1.0 1 0 0 1 1 1 1 Folate receptor family zf-RING_2 PF13639.6 KFQ96282.1 - 2.3e-06 27.8 6.1 4.1e-06 27.0 6.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFQ96282.1 - 6.9e-05 23.1 7.0 0.00014 22.1 7.0 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFQ96282.1 - 0.00045 20.0 5.2 0.00097 19.0 5.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFQ96282.1 - 0.0023 17.8 6.6 0.0039 17.1 6.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFQ96282.1 - 0.0091 15.8 5.0 0.018 14.9 4.9 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFQ96282.1 - 0.0095 16.0 4.9 0.029 14.4 5.0 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KFQ96282.1 - 0.011 15.6 8.3 0.043 13.7 8.3 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 KFQ96282.1 - 0.014 15.4 0.2 0.031 14.3 0.2 1.5 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_11 PF17123.5 KFQ96282.1 - 0.015 15.1 3.9 0.045 13.5 3.9 1.9 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 KFQ96282.1 - 0.039 14.0 3.3 0.16 12.0 3.3 2.0 1 1 1 2 2 2 0 RING-type zinc-finger zf-Di19 PF05605.12 KFQ96282.1 - 0.044 14.1 2.5 0.35 11.2 0.2 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-ribbon_3 PF13248.6 KFQ96282.1 - 0.057 12.8 1.6 2.9 7.4 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Cys_rich_CPXG PF14255.6 KFQ96282.1 - 0.097 12.6 1.5 4.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Cysteine-rich CPXCG FANCL_C PF11793.8 KFQ96282.1 - 0.14 12.3 8.1 3 8.1 8.1 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KFQ96282.1 - 0.17 11.5 7.4 0.48 10.1 7.4 1.8 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-UDP PF14569.6 KFQ96282.1 - 0.42 10.8 5.8 0.92 9.7 5.8 1.6 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_3 PF13920.6 KFQ96282.1 - 0.68 9.8 7.8 3.4 7.6 7.6 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.6 KFQ96283.1 - 4.1e-30 104.2 11.5 8.6e-30 103.1 11.5 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFQ96283.1 - 4.3e-19 68.6 10.6 4.3e-19 68.6 10.6 2.6 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KFQ96283.1 - 0.0007 19.1 0.8 0.0007 19.1 0.8 2.8 3 0 0 3 3 3 1 PHD-finger HALZ PF02183.18 KFQ96283.1 - 0.0061 16.7 2.7 0.0061 16.7 2.7 1.8 2 0 0 2 2 2 1 Homeobox associated leucine zipper DUF4022 PF13214.6 KFQ96283.1 - 0.17 12.2 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4022) PHD PF00628.29 KFQ96283.1 - 0.24 11.3 17.1 2.4 8.1 0.3 3.1 2 0 0 2 2 2 0 PHD-finger DUF2180 PF09947.9 KFQ96283.1 - 2.2 8.3 9.0 2.4 8.2 4.7 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) RAWUL PF16207.5 KFQ96284.1 - 5.2e-17 62.3 0.1 7.6e-17 61.8 0.1 1.3 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like Rad60-SLD PF11976.8 KFQ96284.1 - 0.029 14.2 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Proteasome PF00227.26 KFQ96285.1 - 2.2e-34 118.6 0.0 2.5e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit MICSWaP PF17018.5 KFQ96285.1 - 0.071 12.7 0.0 5.1 6.6 0.0 2.1 2 0 0 2 2 2 0 Spore wall protein PIP5K PF01504.18 KFQ96286.1 - 2e-76 256.8 0.1 2.8e-76 256.3 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase CWC25 PF12542.8 KFQ96287.1 - 2e-21 76.8 0.0 2e-21 76.8 0.0 4.5 4 1 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 KFQ96287.1 - 1.6e-15 57.0 13.8 1.6e-15 57.0 13.8 6.1 6 1 1 7 7 7 1 N-terminal domain of CBF1 interacting co-repressor CIR TCL1_MTCP1 PF01840.17 KFQ96289.1 - 1.2e-16 60.4 0.1 1.2e-16 60.4 0.1 1.0 1 0 0 1 1 1 1 TCL1/MTCP1 family MTCP1 PF08991.10 KFQ96290.1 - 1.8e-09 37.7 6.2 2.1e-09 37.5 6.2 1.1 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type FUN14 PF04930.15 KFQ96291.1 - 1.5e-26 92.6 4.7 1.9e-26 92.3 4.7 1.1 1 0 0 1 1 1 1 FUN14 family SH3BGR PF04908.15 KFQ96291.1 - 0.075 13.2 0.0 8.9 6.5 0.1 2.2 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein SPC12 PF06645.13 KFQ96291.1 - 0.23 11.6 2.2 0.25 11.5 0.3 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) F5_F8_type_C PF00754.25 KFQ96292.1 - 2.2e-55 186.2 4.1 1.6e-27 96.1 0.4 3.2 3 0 0 3 3 3 2 F5/8 type C domain Cu-oxidase_3 PF07732.15 KFQ96292.1 - 1.4e-16 60.6 0.0 0.00011 22.2 0.0 4.7 4 0 0 4 4 4 3 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFQ96292.1 - 1e-14 54.5 8.3 5.8e-09 35.8 0.9 5.2 5 1 0 5 5 5 3 Multicopper oxidase Sad1_UNC PF07738.13 KFQ96292.1 - 0.17 11.9 0.1 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Sad1 / UNC-like C-terminal Guanylate_kin PF00625.21 KFQ96293.1 - 8.9e-61 204.7 0.5 1.3e-60 204.2 0.1 1.5 2 0 0 2 2 2 1 Guanylate kinase PDZ PF00595.24 KFQ96293.1 - 2e-19 69.7 2.6 2.3e-19 69.5 1.0 1.9 2 0 0 2 2 2 1 PDZ domain SH3_2 PF07653.17 KFQ96293.1 - 1.3e-10 40.8 0.0 3.1e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFQ96293.1 - 1.2e-08 34.5 1.0 5.5e-08 32.3 1.0 2.1 1 1 0 1 1 1 1 SH3 domain PDZ_6 PF17820.1 KFQ96293.1 - 5.8e-06 26.1 0.3 1.7e-05 24.6 0.1 2.0 2 0 0 2 2 2 1 PDZ domain SH3_9 PF14604.6 KFQ96293.1 - 2.3e-05 24.2 0.0 5.4e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PDZ_2 PF13180.6 KFQ96293.1 - 0.00013 22.3 0.3 0.00095 19.5 0.1 2.2 2 0 0 2 2 2 1 PDZ domain RsgA_GTPase PF03193.16 KFQ96293.1 - 0.0011 18.9 0.0 0.0072 16.3 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase Tricorn_PDZ PF14685.6 KFQ96293.1 - 0.0017 18.3 0.5 0.23 11.5 0.1 3.2 3 1 0 3 3 3 1 Tricorn protease PDZ domain AAA_7 PF12775.7 KFQ96293.1 - 0.033 13.7 0.0 0.072 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KFQ96293.1 - 0.033 14.2 0.0 0.08 13.0 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase PDZ_4 PF17816.1 KFQ96293.1 - 0.046 14.1 0.1 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 PDZ domain DKCLD PF08068.12 KFQ96294.1 - 3.3e-25 87.9 0.1 1.5e-24 85.8 0.1 2.1 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 KFQ96294.1 - 3.5e-22 78.3 0.3 6.6e-22 77.4 0.3 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 KFQ96294.1 - 4.8e-20 72.4 8.5 2.9e-19 69.9 0.1 3.8 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 KFQ96294.1 - 4.7e-18 64.9 1.0 1.2e-17 63.6 1.0 1.8 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KFQ96294.1 - 0.0028 17.9 0.0 0.0072 16.6 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain GAGA_bind PF06217.12 KFQ96294.1 - 3.9 7.7 13.1 6.1 7.0 13.1 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family PBP_N PF17093.5 KFQ96294.1 - 5.7 7.2 7.6 10 6.4 7.6 1.4 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus EF-hand_7 PF13499.6 KFQ96297.1 - 2.3e-25 88.8 4.5 2.7e-16 59.7 0.7 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KFQ96297.1 - 5.6e-25 85.0 12.9 9.6e-08 31.1 0.1 4.6 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 KFQ96297.1 - 9.9e-23 78.1 5.5 2.9e-07 29.9 0.1 4.7 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 KFQ96297.1 - 2.3e-17 61.6 9.4 6.1e-06 25.5 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KFQ96297.1 - 2.8e-13 49.5 11.5 3e-05 23.8 0.4 4.3 4 1 0 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFQ96297.1 - 1.5e-05 25.3 2.0 0.061 13.6 0.5 3.3 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KFQ96297.1 - 0.00025 21.2 0.1 0.069 13.4 0.0 2.8 3 0 0 3 3 3 1 Dockerin type I domain p25-alpha PF05517.12 KFQ96297.1 - 0.0014 18.8 1.2 0.051 13.7 0.4 2.4 2 0 0 2 2 2 1 p25-alpha Caleosin PF05042.13 KFQ96297.1 - 0.0023 17.9 6.2 0.1 12.5 3.3 3.3 2 1 0 2 2 2 1 Caleosin related protein EF-hand_9 PF14658.6 KFQ96297.1 - 0.0034 17.7 0.1 5.6 7.4 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain IL3 PF02059.15 KFQ96297.1 - 0.0041 17.2 0.1 0.016 15.2 0.0 1.9 2 0 0 2 2 2 1 Interleukin-3 EF-hand_4 PF12763.7 KFQ96297.1 - 0.034 14.1 7.1 9.8 6.2 0.0 3.9 2 1 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand SMC_N PF02463.19 KFQ96298.1 - 4.8e-15 55.6 31.2 4.4e-14 52.5 31.2 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFQ96298.1 - 9.3e-07 28.9 5.3 0.0071 16.2 0.4 2.9 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFQ96298.1 - 1.1e-06 29.3 36.1 1.1e-06 29.3 36.1 6.0 2 2 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KFQ96298.1 - 3.4e-05 23.7 17.8 3.4e-05 23.7 17.8 3.7 2 2 0 2 2 2 1 AAA ATPase domain DUF1474 PF07342.11 KFQ96298.1 - 0.0028 18.2 0.7 0.0028 18.2 0.7 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1474) AAA_29 PF13555.6 KFQ96298.1 - 0.0096 15.7 0.3 0.018 14.8 0.3 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Pox_A_type_inc PF04508.12 KFQ96298.1 - 2.1 8.4 10.1 4.3 7.4 0.4 3.8 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat XPG_I PF00867.18 KFQ96299.1 - 1.1e-25 89.8 0.1 1.1e-25 89.8 0.1 2.6 3 0 0 3 3 3 1 XPG I-region Chromo_2 PF18704.1 KFQ96299.1 - 2e-22 79.2 0.3 5.7e-22 77.8 0.3 1.8 1 0 0 1 1 1 1 Chromatin organization modifier domain 2 A2L_zn_ribbon PF08792.10 KFQ96299.1 - 0.0023 17.6 1.8 0.0068 16.1 1.8 1.8 1 0 0 1 1 1 1 A2L zinc ribbon domain 5_3_exonuc PF01367.20 KFQ96299.1 - 0.058 14.0 0.2 0.42 11.2 0.0 2.3 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold XPG_N PF00752.17 KFQ96299.1 - 0.13 12.8 0.0 0.43 11.1 0.0 1.9 1 0 0 1 1 1 0 XPG N-terminal domain RecR PF02132.15 KFQ96299.1 - 0.24 11.0 1.5 0.83 9.3 1.5 2.0 1 0 0 1 1 1 0 RecR protein HLH PF00010.26 KFQ96300.1 - 1.2e-11 44.4 2.1 1.7e-11 43.9 1.4 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Zona_pellucida PF00100.23 KFQ96301.1 - 8.9e-43 146.9 3.8 2.8e-40 138.8 0.5 2.7 2 1 0 2 2 2 2 Zona pellucida-like domain Ion_trans PF00520.31 KFQ96302.1 - 1.7e-48 165.0 0.8 2.2e-48 164.6 0.8 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFQ96302.1 - 7.7e-31 106.3 0.2 3.2e-30 104.3 0.2 2.1 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFQ96302.1 - 5.6e-12 45.5 3.8 5.6e-12 45.5 3.8 1.9 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.5 KFQ96302.1 - 0.012 15.7 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain adh_short PF00106.25 KFQ96303.1 - 8.1e-18 64.6 0.0 7.3e-17 61.5 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFQ96303.1 - 2.2e-12 47.0 0.0 9.6e-12 45.0 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 5-nucleotidase PF06189.12 KFQ96304.1 - 1.3e-97 325.9 0.0 1.6e-97 325.6 0.0 1.0 1 0 0 1 1 1 1 5'-nucleotidase Herpes_US9 PF06072.11 KFQ96304.1 - 0.13 12.1 0.0 1 9.3 0.0 2.1 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 zf-C2H2 PF00096.26 KFQ96306.1 - 1.9e-13 50.1 25.4 0.00011 22.4 4.5 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ96306.1 - 9.3e-13 48.0 21.4 3e-06 27.4 0.8 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ96306.1 - 8.8e-09 35.5 22.6 0.0066 17.2 2.6 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFQ96306.1 - 1.2e-05 25.1 21.6 0.00011 22.0 1.8 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ96306.1 - 0.0011 19.2 14.2 0.15 12.4 1.3 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding C1_4 PF07975.12 KFQ96306.1 - 0.0014 18.8 10.8 0.25 11.6 5.8 2.8 1 1 2 3 3 3 2 TFIIH C1-like domain Zn-ribbon_8 PF09723.10 KFQ96306.1 - 0.002 18.2 8.3 0.015 15.4 1.7 2.4 2 0 0 2 2 2 2 Zinc ribbon domain XPA_N PF01286.18 KFQ96306.1 - 0.0067 16.4 7.9 0.27 11.3 0.8 3.2 3 0 0 3 3 3 1 XPA protein N-terminal zf-AN1 PF01428.16 KFQ96306.1 - 0.015 15.5 16.8 0.14 12.4 3.2 3.4 2 1 1 3 3 3 0 AN1-like Zinc finger GAGA PF09237.11 KFQ96306.1 - 0.032 14.1 2.6 0.13 12.1 0.6 2.4 1 1 1 2 2 2 0 GAGA factor zf-met PF12874.7 KFQ96306.1 - 0.11 12.9 0.4 0.11 12.9 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type CpXC PF14353.6 KFQ96306.1 - 0.29 11.2 0.1 0.29 11.2 0.1 2.7 1 1 2 3 3 3 0 CpXC protein zf_UBZ PF18439.1 KFQ96306.1 - 0.49 10.0 8.0 13 5.5 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF4379 PF14311.6 KFQ96306.1 - 0.95 9.9 3.3 1.2 9.5 0.3 2.2 2 0 0 2 2 2 0 Probable Zinc-ribbon domain FYVE PF01363.21 KFQ96306.1 - 1.9 8.7 13.9 1.1 9.5 6.7 2.3 1 1 1 2 2 2 0 FYVE zinc finger LIM PF00412.22 KFQ96306.1 - 2.1 8.7 12.5 11 6.4 0.2 2.7 1 1 0 2 2 2 0 LIM domain zf-trcl PF13451.6 KFQ96306.1 - 7.5 6.5 13.0 5.6 6.9 0.4 3.1 3 0 0 3 3 3 0 Probable zinc-ribbon domain Zona_pellucida PF00100.23 KFQ96307.1 - 3.5e-29 102.4 0.8 7.3e-27 94.8 0.1 2.5 2 1 0 2 2 2 2 Zona pellucida-like domain ANAPC4_WD40 PF12894.7 KFQ96308.1 - 1.4e-14 54.1 11.0 1.5e-06 28.4 0.2 7.6 4 2 3 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFQ96308.1 - 9e-06 26.3 11.4 0.67 10.9 0.0 6.6 7 0 0 7 7 7 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KFQ96308.1 - 4.2e-05 22.8 4.1 0.00094 18.3 0.1 4.0 4 0 0 4 4 4 1 Coatomer WD associated region Clathrin PF00637.20 KFQ96308.1 - 0.00046 20.1 3.6 0.00098 19.0 1.6 2.5 1 1 1 2 2 2 1 Region in Clathrin and VPS RPN1_RPN2_N PF17781.1 KFQ96308.1 - 0.00056 19.4 0.4 0.0012 18.3 0.4 1.5 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain DUF410 PF04190.13 KFQ96308.1 - 0.011 15.5 3.1 0.77 9.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF410) eIF2A PF08662.11 KFQ96308.1 - 0.017 15.0 1.7 0.12 12.2 0.5 2.9 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Prok-RING_4 PF14447.6 KFQ96308.1 - 0.17 11.8 4.8 0.48 10.3 4.8 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 A2L_zn_ribbon PF08792.10 KFQ96308.1 - 1 9.2 4.3 3.3 7.5 4.3 2.0 1 0 0 1 1 1 0 A2L zinc ribbon domain Cmc1 PF08583.10 KFQ96308.1 - 1.8 8.6 6.9 0.25 11.4 0.8 2.7 3 0 0 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like VWA PF00092.28 KFQ96309.1 - 1.2e-47 162.4 0.2 1.4e-47 162.1 0.2 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain FXa_inhibition PF14670.6 KFQ96309.1 - 7.2e-31 106.2 60.4 3.6e-08 33.5 9.3 4.3 4 0 0 4 4 4 4 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 KFQ96309.1 - 6.4e-23 80.7 50.0 9.9e-07 28.9 7.6 4.3 4 0 0 4 4 4 4 Calcium-binding EGF domain cEGF PF12662.7 KFQ96309.1 - 1.9e-21 75.7 34.3 7.3e-06 25.8 1.9 4.6 4 0 0 4 4 4 4 Complement Clr-like EGF-like VWA_2 PF13519.6 KFQ96309.1 - 9.8e-20 71.2 0.1 1.4e-19 70.7 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain EGF PF00008.27 KFQ96309.1 - 1.2e-06 28.7 48.9 0.095 13.0 5.7 4.6 4 0 0 4 4 4 4 EGF-like domain EGF_3 PF12947.7 KFQ96309.1 - 0.00072 19.7 42.9 0.21 11.8 6.2 4.8 4 0 0 4 4 4 4 EGF domain zf-NF-X1 PF01422.17 KFQ96309.1 - 0.063 13.3 22.3 3.2 7.9 0.9 4.8 4 0 0 4 4 4 0 NF-X1 type zinc finger Plasmod_Pvs28 PF06247.11 KFQ96309.1 - 0.096 13.0 45.8 1.9 8.8 3.2 4.5 3 1 1 4 4 4 0 Pvs28 EGF domain DUF4215 PF13948.6 KFQ96309.1 - 8.9 6.8 42.1 1.8 9.0 3.5 5.1 3 1 2 5 5 5 0 Domain of unknown function (DUF4215) Mtp PF03821.16 KFQ96310.1 - 5.7e-23 81.7 14.1 1.6e-15 57.3 4.9 2.1 1 1 1 2 2 2 2 Golgi 4-transmembrane spanning transporter DUF4728 PF15860.5 KFQ96310.1 - 0.00015 22.3 2.8 0.00015 22.3 2.8 2.5 2 1 1 3 3 3 2 Domain of unknown function (DUF4728) MG3 PF17791.1 KFQ96310.1 - 0.04 14.2 1.6 1.6 9.0 0.2 2.4 2 0 0 2 2 2 0 Macroglobulin domain MG3 Tetraspanin PF00335.20 KFQ96310.1 - 1 9.0 9.5 0.042 13.6 1.2 2.0 2 0 0 2 2 2 0 Tetraspanin family Kinesin PF00225.23 KFQ96311.1 - 1.4e-92 310.2 0.1 1.4e-92 310.2 0.1 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFQ96311.1 - 8.6e-15 55.0 0.1 5.9e-14 52.2 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding UPF0242 PF06785.11 KFQ96311.1 - 1.8 8.6 12.5 0.64 10.1 6.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CREPT PF16566.5 KFQ96311.1 - 4.1 7.6 9.1 0.72 10.0 2.4 2.8 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour RrnaAD PF00398.20 KFQ96312.1 - 8.1e-44 149.7 0.0 9.9e-44 149.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase UPF0020 PF01170.18 KFQ96312.1 - 0.13 11.9 0.0 0.64 9.7 0.0 1.8 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 RVT_1 PF00078.27 KFQ96313.1 - 0.0028 17.2 0.0 0.0089 15.6 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) 7tm_1 PF00001.21 KFQ96314.1 - 8.5e-36 123.6 0.0 1e-35 123.4 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ96314.1 - 0.00091 18.7 0.1 0.0016 17.9 0.1 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Cyt_bd_oxida_II PF02322.15 KFQ96314.1 - 0.0033 16.8 0.9 0.0072 15.7 0.1 1.7 2 0 0 2 2 2 1 Cytochrome bd terminal oxidase subunit II ArsP_1 PF03773.13 KFQ96314.1 - 0.099 11.8 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Predicted permease ABC2_membrane_3 PF12698.7 KFQ96314.1 - 0.12 11.4 1.4 0.15 11.2 0.1 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein zf-C3HC4_3 PF13920.6 KFQ96316.1 - 9.7e-08 31.8 8.6 9.7e-08 31.8 8.6 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ96316.1 - 2.5e-06 27.2 10.9 2.5e-06 27.2 10.9 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFQ96316.1 - 6.6e-06 25.9 12.3 6.6e-06 25.9 12.3 3.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFQ96316.1 - 2.2e-05 24.4 9.8 2.2e-05 24.4 9.8 3.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFQ96316.1 - 2.9e-05 24.3 11.2 2.9e-05 24.3 11.2 3.7 2 1 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 KFQ96316.1 - 0.00035 20.5 8.9 0.00035 20.5 8.9 3.6 3 0 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFQ96316.1 - 0.0022 17.8 8.6 0.0022 17.8 8.6 3.5 3 1 1 4 4 4 1 Prokaryotic RING finger family 4 FeS PF04060.13 KFQ96317.1 - 0.0021 17.7 0.1 0.0061 16.2 0.0 1.8 2 0 0 2 2 2 1 Putative Fe-S cluster RunxI PF08504.11 KFQ96317.1 - 4.6 8.0 8.6 0.18 12.5 1.8 1.9 2 0 0 2 2 2 0 Runx inhibition domain Cadherin PF00028.17 KFQ96318.1 - 2.3e-91 300.4 0.3 9.7e-20 70.8 0.0 6.3 6 0 0 6 6 6 6 Cadherin domain Cadherin_tail PF15974.5 KFQ96318.1 - 1.8e-46 157.8 2.0 3.8e-46 156.7 2.0 1.6 1 0 0 1 1 1 1 Cadherin C-terminal cytoplasmic tail, catenin-binding region Cadherin_2 PF08266.12 KFQ96318.1 - 3.4e-34 116.5 0.1 2.9e-30 103.9 0.1 4.6 6 0 0 6 6 6 2 Cadherin-like Cadherin_C_2 PF16492.5 KFQ96318.1 - 6.5e-27 94.1 0.5 2e-26 92.5 0.1 2.1 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal RET_CLD1 PF17756.1 KFQ96318.1 - 0.0072 16.6 0.0 4.1 7.7 0.0 3.5 3 0 0 3 3 3 1 RET Cadherin like domain 1 Cadherin_4 PF17803.1 KFQ96318.1 - 0.041 14.5 0.7 0.041 14.5 0.7 5.2 5 1 1 6 6 6 0 Bacterial cadherin-like domain He_PIG PF05345.12 KFQ96318.1 - 0.15 12.3 10.0 0.34 11.1 0.2 5.3 7 0 0 7 7 7 0 Putative Ig domain Big_9 PF17963.1 KFQ96318.1 - 0.29 11.9 14.8 0.087 13.6 1.5 4.8 3 1 1 4 4 4 0 Bacterial Ig domain RasGAP PF00616.19 KFQ96319.1 - 1.9e-27 96.3 4.9 6.1e-19 68.6 0.1 2.7 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase SH2 PF00017.24 KFQ96319.1 - 1.1e-21 76.7 0.0 3.2e-21 75.2 0.0 1.9 1 0 0 1 1 1 1 SH2 domain PH PF00169.29 KFQ96319.1 - 3e-18 66.2 0.2 1.8e-17 63.8 0.1 2.4 2 0 0 2 2 2 1 PH domain C2 PF00168.30 KFQ96319.1 - 3.1e-12 46.7 0.1 6.7e-12 45.6 0.1 1.6 1 0 0 1 1 1 1 C2 domain SH3_1 PF00018.28 KFQ96319.1 - 3.3e-10 39.4 0.0 7e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFQ96319.1 - 5.1e-05 23.1 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 KFQ96319.1 - 0.00039 20.8 1.3 0.0067 16.8 0.6 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain Cyclin_C_2 PF16899.5 KFQ96320.1 - 1.9e-24 86.1 0.0 2.1e-22 79.5 0.0 2.3 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 KFQ96320.1 - 3.3e-09 36.6 0.1 6e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain UBA2_C PF16195.5 KFQ96320.1 - 0.084 13.6 0.6 0.14 12.9 0.6 1.2 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus Cyclin_C PF02984.19 KFQ96320.1 - 0.25 11.5 1.8 1.9 8.6 0.5 2.6 2 2 0 2 2 2 0 Cyclin, C-terminal domain Tmemb_161AB PF10268.9 KFQ96321.1 - 8.6e-213 707.2 15.9 9.7e-213 707.1 15.9 1.0 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB Peptidase_A22B PF04258.13 KFQ96322.1 - 1.1e-103 346.6 8.9 1.3e-103 346.4 8.9 1.0 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 KFQ96322.1 - 2.9e-05 23.7 8.2 6e-05 22.7 8.2 1.4 1 1 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease Presenilin PF01080.17 KFQ96322.1 - 0.00098 18.0 5.1 0.00098 18.0 5.1 1.6 1 1 1 2 2 2 1 Presenilin Ras PF00071.22 KFQ96323.1 - 4.8e-24 84.8 0.0 6e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Ras family DUF2369 PF10179.9 KFQ96323.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) Roc PF08477.13 KFQ96323.1 - 0.14 12.4 0.0 0.39 11.0 0.0 1.7 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RabGAP-TBC PF00566.18 KFQ96324.1 - 1.3e-27 96.9 0.0 1.9e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Mis14 PF08641.12 KFQ96324.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Kinetochore protein Mis14 like Pkinase PF00069.25 KFQ96325.1 - 3e-72 243.2 0.3 3.5e-72 242.9 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ96325.1 - 1.6e-20 73.5 0.0 2.1e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFQ96325.1 - 4.7e-08 33.2 0.0 6.4e-06 26.3 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFQ96325.1 - 0.00035 20.0 0.1 0.00058 19.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFQ96325.1 - 0.0053 15.6 0.1 0.016 14.0 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KFQ96325.1 - 0.0089 15.4 0.1 0.047 13.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 KFQ96325.1 - 0.02 14.5 0.2 0.02 14.5 0.2 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase ABC1 PF03109.16 KFQ96325.1 - 0.067 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 ABC1 family FTA2 PF13095.6 KFQ96325.1 - 0.071 12.7 0.2 1.4 8.5 0.0 2.7 2 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 HLH PF00010.26 KFQ96326.1 - 2.9e-18 65.6 0.3 4.1e-18 65.1 0.3 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ParBc PF02195.18 KFQ96327.1 - 3.3e-07 30.5 0.0 4.1e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain LicD PF04991.13 KFQ96328.1 - 1.7e-06 28.4 0.9 8.2e-06 26.1 0.2 2.4 2 1 1 3 3 3 1 LicD family Choline_transpo PF04515.12 KFQ96329.1 - 2e-102 342.7 36.1 2e-102 342.7 36.1 2.7 2 1 1 3 3 3 1 Plasma-membrane choline transporter DUF4131 PF13567.6 KFQ96329.1 - 2.9 7.5 0.0 2.9 7.5 0.0 4.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) NIPSNAP PF07978.13 KFQ96330.1 - 7.6e-51 170.6 0.1 5.9e-29 100.3 0.1 2.0 2 0 0 2 2 2 2 NIPSNAP Sec7 PF01369.20 KFQ96332.1 - 5.3e-44 150.1 0.2 8.6e-44 149.4 0.2 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KFQ96332.1 - 8.3e-41 139.1 1.7 4.9e-40 136.6 0.7 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KFQ96332.1 - 7.8e-15 55.3 0.2 2.2e-14 53.8 0.2 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFQ96332.1 - 0.0059 17.0 2.5 0.0088 16.4 0.7 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_2 PF08458.10 KFQ96332.1 - 0.012 16.0 0.3 0.025 15.0 0.3 1.5 1 0 0 1 1 1 0 Plant pleckstrin homology-like region Lipase PF00151.19 KFQ96333.1 - 1.1e-120 403.0 0.0 1.3e-120 402.7 0.0 1.1 1 0 0 1 1 1 1 Lipase PLAT PF01477.23 KFQ96333.1 - 2.4e-21 76.5 1.1 4.4e-21 75.6 1.1 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain Abhydrolase_6 PF12697.7 KFQ96333.1 - 0.00047 20.8 0.2 0.00068 20.3 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFQ96333.1 - 0.0037 16.9 0.0 0.0072 16.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold RIG-I_C PF18119.1 KFQ96334.1 - 1.1e-36 125.9 2.9 1.1e-36 125.9 2.9 2.1 2 0 0 2 2 2 1 RIG-I receptor C-terminal domain RIG-I_C-RD PF11648.8 KFQ96334.1 - 1.5e-31 109.1 5.6 7.1e-31 106.9 5.6 2.3 1 0 0 1 1 1 1 C-terminal domain of RIG-I CARD_2 PF16739.5 KFQ96334.1 - 3.1e-29 100.8 7.7 4.6e-20 71.4 0.3 3.2 3 0 0 3 3 3 2 Caspase recruitment domain DEAD PF00270.29 KFQ96334.1 - 1.7e-19 70.3 0.1 5.6e-19 68.6 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFQ96334.1 - 2.5e-17 63.4 0.8 6.9e-16 58.7 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFQ96334.1 - 1.7e-13 50.9 0.0 5.8e-13 49.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_25 PF13481.6 KFQ96334.1 - 0.0075 15.9 0.0 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFQ96334.1 - 0.014 15.8 2.0 0.18 12.1 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KFQ96334.1 - 0.056 13.7 0.0 0.19 12.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KFQ96334.1 - 0.15 11.5 0.6 0.6 9.5 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Aconitase PF00330.20 KFQ96335.1 - 1.8e-180 600.9 0.0 2.2e-180 600.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KFQ96335.1 - 6.5e-46 155.9 0.0 1e-44 152.0 0.0 2.2 2 0 0 2 2 2 1 Aconitase C-terminal domain DAGK_acc PF00609.19 KFQ96336.1 - 3.3e-50 170.5 0.0 7.7e-50 169.3 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KFQ96336.1 - 5.5e-23 81.0 0.0 1.5e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain RA PF00788.23 KFQ96336.1 - 4.7e-17 62.4 1.0 9.1e-10 39.0 0.2 3.4 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain C1_1 PF00130.22 KFQ96336.1 - 1.5e-15 56.8 39.9 1.3e-11 44.2 5.7 3.8 3 1 1 4 4 4 3 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KFQ96336.1 - 0.011 16.0 4.0 0.011 16.0 4.0 3.8 3 1 0 3 3 3 0 C1 domain YusW PF14039.6 KFQ96336.1 - 0.27 11.8 1.2 15 6.1 0.0 2.4 2 0 0 2 2 2 0 YusW-like protein BTB PF00651.31 KFQ96337.1 - 1.5e-24 86.3 0.5 4.5e-24 84.8 0.5 1.9 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFQ96337.1 - 5e-15 55.2 51.3 2.7e-07 30.7 6.2 7.5 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ96337.1 - 4.4e-11 42.6 53.8 0.017 15.6 0.2 6.6 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ96337.1 - 1.4e-10 41.0 60.8 0.022 15.6 0.3 7.0 7 0 0 7 7 6 6 C2H2-type zinc finger zf-met PF12874.7 KFQ96337.1 - 1.9e-06 28.1 5.6 0.00028 21.2 0.9 6.6 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFQ96337.1 - 0.00087 19.2 46.7 0.0083 16.1 1.8 6.5 6 1 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ96337.1 - 0.0064 16.7 0.4 0.0064 16.7 0.4 6.7 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFQ96337.1 - 0.098 12.5 5.2 3 7.7 0.0 4.1 4 0 0 4 4 4 0 GAGA factor Zn-ribbon_8 PF09723.10 KFQ96337.1 - 0.88 9.7 25.0 1.6 8.9 3.6 4.6 3 2 1 4 4 4 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 KFQ96337.1 - 2.3 9.0 21.6 8.1 7.3 3.5 4.0 3 1 1 4 4 4 0 zinc-ribbon family zf-C2H2_2 PF12756.7 KFQ96337.1 - 5.3 7.4 36.8 4.9 7.6 2.4 6.6 2 2 3 6 6 6 0 C2H2 type zinc-finger (2 copies) Ras PF00071.22 KFQ96338.1 - 1.5e-15 57.1 0.3 1.7e-15 57.0 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ96338.1 - 2.7e-12 47.0 0.2 3e-12 46.8 0.2 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ96338.1 - 0.0034 16.9 0.0 0.0039 16.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFQ96338.1 - 0.019 14.4 0.1 0.023 14.2 0.1 1.0 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 KFQ96338.1 - 0.046 13.4 0.0 0.046 13.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KFQ96338.1 - 0.076 12.4 0.0 0.076 12.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein MMR_HSR1 PF01926.23 KFQ96338.1 - 0.11 12.6 0.1 0.12 12.5 0.1 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase Pkinase PF00069.25 KFQ96339.1 - 2.5e-47 161.5 0.0 4e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain POLO_box PF00659.18 KFQ96339.1 - 3.8e-35 119.9 1.9 1.9e-16 60.0 0.5 2.5 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_Tyr PF07714.17 KFQ96339.1 - 2.3e-25 89.4 0.0 4.2e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFQ96339.1 - 4.3e-06 25.8 0.0 7.8e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFQ96339.1 - 0.00089 18.7 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Vasculin PF15337.6 KFQ96340.1 - 1.4e-41 141.3 3.4 1.4e-41 141.3 3.4 2.7 2 1 0 3 3 3 1 Vascular protein family Vasculin-like 1 ELM2 PF01448.24 KFQ96341.1 - 2.2e-11 44.3 0.2 7.9e-11 42.5 0.2 2.0 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-binding PF00249.31 KFQ96341.1 - 2.3e-06 27.7 0.1 5.5e-06 26.5 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFQ96341.1 - 0.0023 17.8 0.1 0.007 16.2 0.1 1.8 1 1 0 1 1 1 1 Myb DNA-binding like Dymeclin PF09742.9 KFQ96343.1 - 4.5e-20 71.6 1.3 4.8e-20 71.5 1.3 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein F5_F8_type_C PF00754.25 KFQ96344.1 - 2.1e-16 60.2 0.7 2.3e-16 60.1 0.7 1.0 1 0 0 1 1 1 1 F5/8 type C domain CHB_HEX_C_1 PF13290.6 KFQ96344.1 - 0.1 12.7 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain PDEase_I PF00233.19 KFQ96345.1 - 1.3e-84 283.7 7.4 1.9e-84 283.1 7.4 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.12 KFQ96345.1 - 9.9e-28 95.8 0.1 2e-27 94.8 0.1 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal DUF1848 PF08902.11 KFQ96345.1 - 0.023 14.4 0.1 0.059 13.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) HRG PF16954.5 KFQ96347.1 - 8.9e-22 77.2 13.1 1.7e-21 76.4 5.8 2.2 2 0 0 2 2 2 2 Haem-transporter, endosomal/lysosomal, haem-responsive gene 7tm_1 PF00001.21 KFQ96347.1 - 0.3 10.4 7.7 0.36 10.1 7.7 1.0 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) HLH PF00010.26 KFQ96348.1 - 2.6e-16 59.3 0.4 4.2e-16 58.6 0.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_51 PF18558.1 KFQ96348.1 - 0.0017 18.2 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain DUF773 PF05600.12 KFQ96348.1 - 0.019 13.7 0.1 0.023 13.5 0.1 1.0 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 DUF390 PF04094.14 KFQ96348.1 - 0.059 11.7 0.4 0.07 11.4 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF390) RhoGAP PF00620.27 KFQ96349.1 - 1.6e-44 151.4 0.0 3.3e-44 150.4 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 KFQ96349.1 - 1.8e-07 30.9 2.7 3.4e-07 30.0 2.7 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Cep57_CLD PF14073.6 KFQ96349.1 - 0.0091 16.0 3.8 0.018 15.1 3.8 1.4 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 TonB_2 PF13103.6 KFQ96349.1 - 0.011 16.0 0.1 0.037 14.3 0.1 1.9 1 0 0 1 1 1 0 TonB C terminal APC_N_CC PF16689.5 KFQ96349.1 - 0.015 15.3 0.6 0.039 14.0 0.6 1.8 1 1 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain DUF2968 PF11180.8 KFQ96349.1 - 0.071 12.7 7.7 0.12 12.0 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) zf-CCHC_6 PF15288.6 KFQ96349.1 - 0.16 11.8 2.2 0.42 10.5 2.2 1.7 1 0 0 1 1 1 0 Zinc knuckle Spc7 PF08317.11 KFQ96349.1 - 0.44 9.4 8.7 0.7 8.7 8.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein ASC PF00858.24 KFQ96350.1 - 1.7e-105 353.6 0.6 2e-105 353.3 0.6 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DUF4074 PF13293.6 KFQ96350.1 - 0.23 11.8 1.0 0.41 11.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4074) SWIB PF02201.18 KFQ96351.1 - 5.8e-25 87.0 0.2 1.5e-24 85.7 0.2 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain NAD_Gly3P_dh_N PF01210.23 KFQ96352.1 - 2.6e-55 186.7 0.5 4.4e-55 185.9 0.1 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KFQ96352.1 - 2.1e-50 170.7 0.4 4.1e-50 169.7 0.2 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 KFQ96352.1 - 0.0013 19.3 3.1 0.018 15.6 0.4 3.3 3 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent GerD PF17898.1 KFQ96352.1 - 0.068 13.1 0.1 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Spore germination GerD central core domain DUF643 PF04867.12 KFQ96352.1 - 0.092 13.4 0.0 0.2 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF643) KH_1 PF00013.29 KFQ96352.1 - 0.6 10.0 2.1 0.74 9.7 0.0 2.2 3 0 0 3 3 3 0 KH domain TRAM_LAG1_CLN8 PF03798.16 KFQ96353.1 - 2.9e-41 141.4 29.2 3.4e-41 141.2 29.2 1.0 1 0 0 1 1 1 1 TLC domain Homeodomain PF00046.29 KFQ96353.1 - 3.7e-07 29.9 0.2 6.4e-07 29.1 0.2 1.4 1 0 0 1 1 1 1 Homeodomain LIM PF00412.22 KFQ96354.1 - 4.2e-12 46.1 3.7 8.8e-12 45.1 3.7 1.6 1 0 0 1 1 1 1 LIM domain La PF05383.17 KFQ96355.1 - 3.3e-18 65.5 0.2 6.3e-18 64.6 0.2 1.5 1 0 0 1 1 1 1 La domain bZIP_1 PF00170.21 KFQ96356.1 - 2.9e-21 75.3 9.0 4.7e-21 74.7 9.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor pKID PF02173.17 KFQ96356.1 - 1.1e-18 66.4 5.6 3e-18 65.0 5.6 1.8 1 0 0 1 1 1 1 pKID domain bZIP_2 PF07716.15 KFQ96356.1 - 6.5e-09 35.7 8.1 1.2e-08 34.9 8.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFQ96356.1 - 0.00024 21.6 4.8 0.00065 20.2 4.8 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor ASD2 PF08687.11 KFQ96356.1 - 0.011 15.3 1.5 0.011 15.3 1.5 1.7 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Rh5 PF18515.1 KFQ96356.1 - 0.034 13.5 1.5 0.046 13.0 1.5 1.2 1 0 0 1 1 1 0 Rh5 coiled-coil domain Trypsin PF00089.26 KFQ96357.1 - 1.2e-70 237.8 0.1 1.3e-70 237.6 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFQ96357.1 - 8.4e-06 26.8 0.0 1.3e-05 26.1 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFQ96357.1 - 0.00014 22.2 0.0 0.00024 21.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Methyltransf_11 PF08241.12 KFQ96358.1 - 5.1e-17 62.3 0.0 8.2e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFQ96358.1 - 5.3e-15 55.6 0.0 7e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFQ96358.1 - 2.3e-11 44.3 0.0 3.7e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFQ96358.1 - 1.1e-10 42.1 0.0 2e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFQ96358.1 - 1.3e-07 31.2 0.0 1.6e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KFQ96358.1 - 1.1e-06 28.5 0.0 1.5e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KFQ96358.1 - 0.00052 19.9 0.0 0.00097 19.0 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 KFQ96358.1 - 0.024 13.2 0.1 0.031 12.9 0.1 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.12 KFQ96358.1 - 0.063 12.9 0.0 0.095 12.3 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_11 PF08241.12 KFQ96359.1 - 1.2e-15 57.9 0.0 1.9e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFQ96359.1 - 3.3e-12 46.5 0.0 4.8e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFQ96359.1 - 1.8e-10 41.4 0.0 1.9e-09 38.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFQ96359.1 - 1.6e-09 38.4 0.0 2.8e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFQ96359.1 - 1.8e-08 34.0 0.0 2.5e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KFQ96359.1 - 1e-06 28.6 0.1 7.6e-06 25.8 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KFQ96359.1 - 4e-06 26.9 0.0 5.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase ANAPC4 PF12896.7 KFQ96359.1 - 0.023 14.2 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 HbrB PF08539.11 KFQ96359.1 - 0.086 12.8 0.5 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 HbrB-like Methyltransf_24 PF13578.6 KFQ96359.1 - 0.091 13.8 0.0 0.19 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ank_2 PF12796.7 KFQ96360.1 - 3.8e-20 72.2 0.2 1.3e-15 57.7 0.1 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFQ96360.1 - 3.5e-16 59.0 0.6 4e-07 30.2 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFQ96360.1 - 1.4e-12 47.9 0.1 0.00022 21.7 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KFQ96360.1 - 1.1e-10 41.5 0.5 0.00084 19.7 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KFQ96360.1 - 5.1e-09 35.6 0.3 0.00084 19.6 0.1 3.7 4 0 0 4 4 4 2 Ankyrin repeat Pkinase_Tyr PF07714.17 KFQ96361.1 - 4.5e-37 127.7 0.0 9.4e-37 126.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ96361.1 - 8.5e-36 123.7 0.0 1.3e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.12 KFQ96361.1 - 1.1e-14 53.6 0.1 2.2e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Pkinase_fungal PF17667.1 KFQ96361.1 - 0.00081 18.3 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFQ96361.1 - 0.014 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFQ96361.1 - 0.1 11.5 0.1 0.18 10.7 0.1 1.6 1 1 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KFQ96361.1 - 0.1 12.2 0.0 0.27 10.9 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 KFQ96362.1 - 4e-34 118.2 0.0 5.3e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ96362.1 - 1.5e-31 109.6 0.0 2.1e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.12 KFQ96362.1 - 2.1e-14 52.7 0.6 3.8e-14 51.9 0.6 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Pkinase_fungal PF17667.1 KFQ96362.1 - 2.6e-05 23.2 0.9 0.0001 21.3 0.1 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFQ96362.1 - 0.0022 18.0 0.0 0.0068 16.4 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFQ96362.1 - 0.045 12.7 0.0 0.12 11.3 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain FTA2 PF13095.6 KFQ96362.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Hormone_recep PF00104.30 KFQ96363.1 - 1.5e-35 122.7 0.0 2.1e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFQ96363.1 - 2.7e-18 66.2 11.7 5.1e-18 65.3 11.7 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) ATG101 PF07855.12 KFQ96364.1 - 3.2e-42 144.1 0.1 4.2e-42 143.7 0.1 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 FH2 PF02181.23 KFQ96365.1 - 3.1e-86 289.8 2.5 3.1e-86 289.8 2.5 2.3 2 1 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KFQ96365.1 - 4e-17 62.4 5.2 3.8e-13 49.4 0.6 4.0 4 0 0 4 4 4 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KFQ96365.1 - 5.6e-14 52.2 6.4 2.2e-12 47.0 6.4 2.4 2 0 0 2 2 2 1 Diaphanous FH3 Domain COG2 PF06148.11 KFQ96365.1 - 0.0083 16.2 5.8 0.02 15.0 4.5 2.2 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 CCAP PF11105.8 KFQ96365.1 - 0.12 12.4 2.6 0.75 9.8 0.8 2.4 2 0 0 2 2 2 0 Arthropod cardioacceleratory peptide 2a UPF0242 PF06785.11 KFQ96365.1 - 0.15 12.2 7.6 0.28 11.3 7.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DHR10 PF18595.1 KFQ96365.1 - 0.41 10.7 17.4 0.71 10.0 14.0 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF1539 PF07560.11 KFQ96365.1 - 0.9 9.6 5.0 0.63 10.1 0.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) FlaC_arch PF05377.11 KFQ96365.1 - 2.6 8.5 9.6 0.72 10.3 1.5 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) ORF6C PF10552.9 KFQ96365.1 - 2.8 8.1 5.7 5.2 7.2 4.3 2.0 2 0 0 2 2 2 0 ORF6C domain FlxA PF14282.6 KFQ96365.1 - 4.4 7.4 5.5 9.6 6.3 1.4 2.6 1 1 1 2 2 2 0 FlxA-like protein Csm1_N PF18504.1 KFQ96365.1 - 9.3 6.7 11.6 6.7 7.1 0.0 3.3 2 1 1 3 3 3 0 Csm1 N-terminal domain Bax1-I PF01027.20 KFQ96366.1 - 1.7e-31 109.7 18.2 1.5e-28 100.0 18.2 2.0 1 1 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 CbtA PF09490.10 KFQ96366.1 - 0.19 11.5 4.3 0.28 10.9 4.3 1.3 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Macro PF01661.21 KFQ96368.1 - 2.4e-28 98.6 0.0 4.3e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 Macro domain Histone_H2A_C PF16211.5 KFQ96368.1 - 6.8e-18 64.1 1.5 6.8e-18 64.1 1.5 2.6 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.24 KFQ96368.1 - 1.4e-15 57.8 1.9 3e-14 53.5 0.0 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFQ96368.1 - 0.0048 17.2 0.0 0.017 15.4 0.0 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1764 PF08576.10 KFQ96368.1 - 0.014 16.3 1.7 0.033 15.1 1.7 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Clp_N PF02861.20 KFQ96368.1 - 0.093 12.9 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Clp amino terminal domain, pathogenicity island component YihI PF04220.12 KFQ96368.1 - 0.12 12.1 5.5 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Der GTPase activator (YihI) OAR PF03826.17 KFQ96369.1 - 9.8e-08 31.6 1.3 2e-07 30.6 1.3 1.6 1 0 0 1 1 1 1 OAR domain Homeodomain PF00046.29 KFQ96369.1 - 0.055 13.3 7.4 0.091 12.6 7.4 1.3 1 0 0 1 1 1 0 Homeodomain Pterin_4a PF01329.19 KFQ96370.1 - 6e-32 109.7 0.1 6.7e-32 109.5 0.1 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase IF-2 PF11987.8 KFQ96370.1 - 0.029 14.5 0.0 0.13 12.4 0.0 1.8 1 1 1 2 2 2 0 Translation-initiation factor 2 Thioredoxin PF00085.20 KFQ96371.1 - 5.5e-10 39.2 0.0 8.8e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KFQ96371.1 - 0.19 11.0 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF5568 PF17724.1 KFQ96372.1 - 3.9e-97 323.5 10.5 4.3e-97 323.3 10.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5568) CAML PF14963.6 KFQ96373.1 - 4e-114 381.3 0.0 4.5e-114 381.2 0.0 1.0 1 0 0 1 1 1 1 Calcium signal-modulating cyclophilin ligand Sec23_trunk PF04811.15 KFQ96374.1 - 1.9e-86 289.6 0.2 3.8e-86 288.6 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KFQ96374.1 - 1.4e-24 85.8 0.7 3.9e-24 84.4 0.7 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KFQ96374.1 - 1.3e-20 73.9 0.0 3.5e-20 72.6 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KFQ96374.1 - 9.1e-15 54.4 4.5 2.2e-14 53.2 4.5 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KFQ96374.1 - 7.8e-10 38.5 0.0 1.8e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Sen15 PF09631.10 KFQ96374.1 - 0.071 13.4 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 Sen15 protein Arf PF00025.21 KFQ96375.1 - 2.2e-61 206.3 0.0 2.5e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KFQ96375.1 - 5.4e-10 39.0 0.0 1.2e-07 31.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KFQ96375.1 - 3.8e-09 36.2 0.0 4.8e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KFQ96375.1 - 2.3e-07 31.0 0.0 5.1e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFQ96375.1 - 1.5e-06 27.9 0.0 1.6e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KFQ96375.1 - 3.2e-06 27.2 0.0 4.6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFQ96375.1 - 0.00072 19.1 0.0 0.0084 15.7 0.0 1.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Metalloenzyme PF01676.18 KFQ96375.1 - 0.004 16.6 0.0 0.056 12.8 0.0 2.0 1 1 1 2 2 2 1 Metalloenzyme superfamily Gtr1_RagA PF04670.12 KFQ96375.1 - 0.0086 15.5 0.0 0.0097 15.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region zf-HC5HC2H_2 PF13832.6 KFQ96376.1 - 9.1e-30 103.1 8.0 9.1e-30 103.1 8.0 2.9 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFQ96376.1 - 3.5e-23 81.6 8.1 3.5e-23 81.6 8.1 3.7 4 0 0 4 4 4 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KFQ96376.1 - 2.5e-12 46.1 7.0 2.5e-12 46.1 7.0 4.0 5 0 0 5 5 5 1 PHD-finger PHD PF00628.29 KFQ96376.1 - 2.6e-10 40.0 7.8 2.6e-10 40.0 7.8 3.3 3 0 0 3 3 3 2 PHD-finger EPL1 PF10513.9 KFQ96376.1 - 1.7e-06 28.5 0.2 1.7e-06 28.5 0.2 3.1 4 1 0 4 4 4 1 Enhancer of polycomb-like C1_1 PF00130.22 KFQ96376.1 - 0.0048 16.8 4.0 0.0048 16.8 4.0 3.3 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FerA PF08165.11 KFQ96376.1 - 0.14 12.1 1.6 0.28 11.2 0.2 2.1 2 0 0 2 2 2 0 FerA (NUC095) domain C1_2 PF03107.16 KFQ96376.1 - 0.6 10.5 24.6 0.081 13.3 5.0 3.4 3 0 0 3 3 3 0 C1 domain UQ_con PF00179.26 KFQ96377.1 - 2.6e-46 156.7 0.2 6.8e-39 132.7 0.2 2.0 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme RWD PF05773.22 KFQ96377.1 - 0.0012 19.1 0.1 0.0017 18.7 0.1 1.3 1 0 0 1 1 1 1 RWD domain Citrate_bind PF16114.5 KFQ96377.1 - 0.0055 16.2 0.0 0.0084 15.6 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding UEV PF05743.13 KFQ96377.1 - 0.02 14.7 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 UEV domain Metallophos PF00149.28 KFQ96378.1 - 7.7e-35 121.2 0.6 1.2e-34 120.7 0.5 1.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KFQ96378.1 - 0.017 14.7 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF5378 PF17349.2 KFQ96378.1 - 0.083 12.2 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Skp1_POZ PF03931.15 KFQ96379.1 - 2.2e-30 104.6 0.7 4.9e-30 103.5 0.2 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 KFQ96379.1 - 2.4e-30 104.4 1.6 4.7e-30 103.5 1.6 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain CTNNB1_binding PF08347.11 KFQ96380.1 - 4.5e-35 121.7 5.0 4.5e-35 121.7 5.0 2.1 3 0 0 3 3 3 1 N-terminal CTNNB1 binding HMG_box PF00505.19 KFQ96380.1 - 1.3e-22 79.9 1.1 2.8e-22 78.9 1.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFQ96380.1 - 5.3e-09 36.5 1.4 1.6e-08 35.0 1.4 1.8 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 KFQ96380.1 - 0.014 14.7 0.1 0.022 14.1 0.1 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Mucin-like PF16058.5 KFQ96381.1 - 0.00046 20.2 1.3 0.37 10.9 0.2 2.3 1 1 1 2 2 2 2 Mucin-like Peptidase_A6 PF01829.16 KFQ96381.1 - 0.048 13.0 0.6 7.7 5.7 0.1 2.1 1 1 1 2 2 2 0 Peptidase A6 family Porin_3 PF01459.22 KFQ96382.1 - 3.7e-72 243.0 5.0 4.1e-72 242.9 5.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin SusE PF14292.6 KFQ96382.1 - 0.063 13.5 2.2 0.066 13.4 0.4 2.0 2 0 0 2 2 2 0 SusE outer membrane protein KCT2 PF17818.1 KFQ96383.1 - 4.6e-90 300.7 3.5 4.6e-90 300.7 3.5 1.4 2 0 0 2 2 2 1 Keratinocyte-associated gene product TMEM40 PF15817.5 KFQ96383.1 - 0.096 12.4 0.1 0.24 11.1 0.1 1.7 2 0 0 2 2 2 0 Transmembrane protein 40 family GAT PF03127.14 KFQ96383.1 - 3 8.2 9.0 0.27 11.5 0.6 2.9 2 1 1 3 3 3 0 GAT domain Ig_3 PF13927.6 KFQ96384.1 - 8.4e-29 100.0 0.2 2.5e-17 63.2 0.1 3.6 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFQ96384.1 - 3.4e-26 91.1 0.0 4.9e-16 58.6 0.0 3.6 4 0 0 4 4 3 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFQ96384.1 - 5.4e-16 58.7 0.0 1.2e-08 35.1 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFQ96384.1 - 7.3e-15 54.9 0.0 3.4e-07 30.4 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain Kazal_2 PF07648.15 KFQ96384.1 - 2.2e-09 37.3 5.1 6.8e-09 35.7 5.1 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain EF-hand_1 PF00036.32 KFQ96384.1 - 1.2e-08 33.9 0.1 3.4e-05 23.1 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KFQ96384.1 - 2.1e-08 33.3 0.3 0.0029 17.0 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFQ96384.1 - 8.1e-07 28.5 1.4 0.0044 16.8 0.4 2.9 2 0 0 2 2 2 2 EF-hand domain V-set PF07686.17 KFQ96384.1 - 4.8e-06 26.7 2.4 0.23 11.7 0.1 4.0 3 1 0 3 3 2 2 Immunoglobulin V-set domain Kazal_1 PF00050.21 KFQ96384.1 - 1.2e-05 25.2 7.5 3.5e-05 23.7 7.5 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.6 KFQ96384.1 - 1.3e-05 25.5 4.2 3.1e-05 24.3 4.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair Ig_6 PF18452.1 KFQ96384.1 - 3e-05 23.5 0.0 0.017 14.7 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin domain SPARC_Ca_bdg PF10591.9 KFQ96384.1 - 0.00013 22.2 0.4 0.00026 21.3 0.4 1.5 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region C1-set PF07654.15 KFQ96384.1 - 0.00047 20.5 0.1 0.05 14.0 0.0 3.6 4 0 0 4 4 4 1 Immunoglobulin C1-set domain C2-set_2 PF08205.12 KFQ96384.1 - 0.00068 19.6 0.0 0.32 11.1 0.0 2.9 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain EF-hand_8 PF13833.6 KFQ96384.1 - 0.001 18.9 0.5 0.08 12.8 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair Dockerin_1 PF00404.18 KFQ96384.1 - 0.0094 16.1 0.2 0.072 13.3 0.0 2.4 2 0 0 2 2 2 1 Dockerin type I domain RasGEF_N PF00618.20 KFQ96385.1 - 1.3e-14 54.2 0.4 4.6e-13 49.3 0.4 2.5 1 1 0 1 1 1 1 RasGEF N-terminal motif RA PF00788.23 KFQ96385.1 - 2.9e-12 47.1 0.0 9e-12 45.5 0.0 2.0 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain cNMP_binding PF00027.29 KFQ96385.1 - 6.3e-12 45.4 0.0 6.2e-07 29.4 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PDZ PF00595.24 KFQ96385.1 - 1.2e-11 44.7 0.0 2.5e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFQ96385.1 - 1.9e-10 40.5 0.0 3.8e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFQ96385.1 - 0.00013 22.2 0.0 0.00035 20.8 0.0 1.7 1 0 0 1 1 1 1 PDZ domain FNIP_M PF14637.6 KFQ96386.1 - 5e-89 298.2 0.0 8.7e-89 297.4 0.0 1.4 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain FNIP_C PF14638.6 KFQ96386.1 - 2.4e-72 242.6 0.1 6e-72 241.3 0.1 1.7 1 0 0 1 1 1 1 Folliculin-interacting protein C-terminus FNIP_N PF14636.6 KFQ96386.1 - 1.6e-25 90.9 11.9 3.8e-25 89.7 2.3 3.8 3 1 0 3 3 3 1 Folliculin-interacting protein N-terminus AMP-binding PF00501.28 KFQ96388.1 - 1.3e-108 363.4 0.0 1.8e-108 362.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFQ96388.1 - 7.4e-05 23.6 0.0 0.00019 22.3 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain P4Ha_N PF08336.11 KFQ96389.1 - 4.9e-40 136.7 0.4 4.9e-40 136.7 0.4 1.8 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 KFQ96389.1 - 7.5e-16 58.8 0.0 1.9e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KFQ96389.1 - 6.4e-06 26.6 0.0 1.5e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SPO22 PF08631.10 KFQ96389.1 - 0.11 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like DUF4749 PF15936.5 KFQ96390.1 - 3.8e-21 76.0 0.2 7.4e-21 75.1 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4749) LIM PF00412.22 KFQ96390.1 - 8.5e-15 54.7 3.7 1.7e-14 53.8 3.7 1.4 1 0 0 1 1 1 1 LIM domain PDZ PF00595.24 KFQ96390.1 - 6.4e-11 42.5 0.1 1.3e-10 41.4 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFQ96390.1 - 2.7e-07 30.3 0.0 5.8e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFQ96390.1 - 0.003 17.8 0.0 0.0056 17.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain zf-SNAP50_C PF12251.8 KFQ96390.1 - 0.28 10.8 2.2 1.4 8.6 0.8 2.1 1 1 1 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal Sugar_tr PF00083.24 KFQ96391.1 - 6.6e-28 97.8 18.2 9.5e-28 97.2 18.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFQ96391.1 - 8e-23 80.9 51.6 2.7e-21 75.9 33.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFQ96392.1 - 5.6e-26 91.4 19.6 8.6e-26 90.8 19.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFQ96392.1 - 2.6e-21 75.9 60.3 1.1e-18 67.4 33.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily IRF PF00605.17 KFQ96393.1 - 2e-40 137.3 0.7 3.9e-40 136.4 0.7 1.5 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor IL5 PF02025.15 KFQ96394.1 - 4e-09 36.8 0.3 5.1e-09 36.4 0.3 1.1 1 0 0 1 1 1 1 Interleukin 5 RIH_assoc PF08454.11 KFQ96394.1 - 6.9e-05 22.6 1.6 9.3e-05 22.2 1.6 1.4 1 1 0 1 1 1 1 RyR and IP3R Homology associated DUF1882 PF08966.11 KFQ96394.1 - 0.096 12.9 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1882) AAA_23 PF13476.6 KFQ96395.1 - 1.7e-33 116.8 4.1 1.7e-33 116.8 4.1 9.5 2 1 3 5 5 5 1 AAA domain AAA_21 PF13304.6 KFQ96395.1 - 2.5e-12 47.2 6.0 8.4e-06 25.8 0.0 4.1 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad50_zn_hook PF04423.14 KFQ96395.1 - 3e-12 46.2 0.0 3e-12 46.2 0.0 6.0 6 0 0 6 6 6 1 Rad50 zinc hook motif AAA_15 PF13175.6 KFQ96395.1 - 1e-09 38.6 2.6 1e-09 38.6 2.6 5.8 1 1 4 5 5 5 2 AAA ATPase domain SbcCD_C PF13558.6 KFQ96395.1 - 9.7e-07 29.0 0.0 4.4e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 KFQ96395.1 - 1.9e-05 24.2 0.1 1.9e-05 24.2 0.1 3.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFQ96395.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2703 PF10865.8 KFQ96395.1 - 0.029 14.5 0.5 0.029 14.5 0.5 6.0 5 2 0 7 7 7 0 Domain of unknown function (DUF2703) AAA_19 PF13245.6 KFQ96395.1 - 0.11 12.9 4.0 14 6.0 0.1 4.2 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KFQ96395.1 - 0.48 10.8 0.0 0.48 10.8 0.0 4.7 5 2 0 5 5 5 0 AAA ATPase domain IL4 PF00727.18 KFQ96396.1 - 7.9e-10 38.9 0.4 1.2e-09 38.4 0.4 1.2 1 0 0 1 1 1 1 Interleukin 4 IL13 PF03487.13 KFQ96396.1 - 0.00012 21.9 0.2 0.00018 21.3 0.2 1.3 1 0 0 1 1 1 1 Interleukin-13 Kinesin PF00225.23 KFQ96397.1 - 4.6e-122 407.1 0.1 1.3e-121 405.7 0.1 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFQ96397.1 - 5.2e-27 94.6 0.1 3.7e-26 91.9 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding AAA_22 PF13401.6 KFQ96397.1 - 0.43 10.9 8.7 1.9 8.8 0.0 3.3 3 1 0 3 3 3 0 AAA domain Cyclin_N PF00134.23 KFQ96398.1 - 4.8e-21 74.8 0.6 8.2e-21 74.1 0.6 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFQ96398.1 - 0.044 13.9 0.8 0.11 12.6 0.1 1.9 2 0 0 2 2 2 0 Cyclin, C-terminal domain Septin PF00735.18 KFQ96399.1 - 3.3e-96 321.9 2.3 3.3e-96 321.9 2.3 2.0 2 1 1 3 3 3 1 Septin MMR_HSR1 PF01926.23 KFQ96399.1 - 4.4e-06 26.7 0.0 4.4e-06 26.7 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFQ96399.1 - 0.00017 21.2 6.1 1.2 8.6 0.9 3.3 3 0 0 3 3 3 3 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFQ96399.1 - 0.00027 21.4 0.1 0.00098 19.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFQ96399.1 - 0.00048 20.1 7.0 0.0041 17.0 0.0 3.5 3 2 0 3 3 3 1 RsgA GTPase Roc PF08477.13 KFQ96399.1 - 0.00049 20.3 0.1 0.0018 18.5 0.0 2.0 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KFQ96399.1 - 0.00079 19.7 1.9 0.0013 19.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KFQ96399.1 - 0.0041 17.6 2.4 0.018 15.5 0.0 2.5 2 0 0 2 2 2 1 ABC transporter Ras PF00071.22 KFQ96399.1 - 0.0069 16.0 0.7 0.019 14.6 0.0 2.1 2 0 0 2 2 2 1 Ras family AAA_7 PF12775.7 KFQ96399.1 - 0.0072 15.9 0.0 0.019 14.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KFQ96399.1 - 0.032 14.6 0.0 0.098 13.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Microtub_bd PF16796.5 KFQ96399.1 - 0.091 12.7 0.0 0.091 12.7 0.0 2.8 2 1 0 2 2 1 0 Microtubule binding AAA_24 PF13479.6 KFQ96399.1 - 0.092 12.5 1.0 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Atg14 PF10186.9 KFQ96399.1 - 0.095 11.8 12.9 0.27 10.3 12.9 1.8 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_29 PF13555.6 KFQ96399.1 - 0.17 11.7 0.1 0.46 10.3 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KFQ96399.1 - 0.19 12.2 18.9 0.45 11.0 0.4 2.5 2 1 0 2 2 2 0 AAA domain IMD PF08397.11 KFQ96399.1 - 0.2 11.0 13.1 0.39 10.1 13.1 1.4 1 0 0 1 1 1 0 IRSp53/MIM homology domain Dynamin_N PF00350.23 KFQ96399.1 - 0.34 11.0 8.8 2.3 8.3 0.2 3.1 2 1 0 2 2 2 0 Dynamin family Fzo_mitofusin PF04799.13 KFQ96399.1 - 0.57 9.7 9.3 0.39 10.2 7.3 1.8 2 0 0 2 2 2 0 fzo-like conserved region DUF87 PF01935.17 KFQ96399.1 - 0.89 9.6 8.8 0.91 9.6 0.0 2.6 3 0 0 3 3 3 0 Helicase HerA, central domain Exonuc_VII_L PF02601.15 KFQ96399.1 - 2.8 7.4 11.0 5.5 6.5 11.0 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP_bind_1 PF03029.17 KFQ96399.1 - 5.2 6.8 8.1 23 4.7 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein ASD2 PF08687.11 KFQ96400.1 - 2.8e-65 220.8 19.6 3.6e-64 217.1 19.6 1.9 1 1 0 1 1 1 1 Apx/Shroom domain ASD2 HXXSHH PF07586.11 KFQ96400.1 - 0.22 11.1 3.8 0.28 10.7 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) DUF2721 PF11026.8 KFQ96400.1 - 0.55 10.1 3.1 1.3 9.0 3.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) DUF5320 PF17253.2 KFQ96400.1 - 0.92 10.6 7.4 7.4 7.7 1.0 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5320) Prefoldin PF02996.17 KFQ96400.1 - 3 7.8 9.3 8.3 6.4 0.6 3.1 2 1 1 3 3 3 0 Prefoldin subunit PCRF PF03462.18 KFQ96400.1 - 3.7 7.4 7.9 3.5 7.4 4.9 1.9 2 0 0 2 2 2 0 PCRF domain TMPIT PF07851.13 KFQ96400.1 - 5.7 6.1 6.8 3 7.0 4.9 1.5 2 0 0 2 2 2 0 TMPIT-like protein ASD1 PF08688.10 KFQ96401.1 - 9.9e-40 136.8 9.9 9.9e-40 136.8 9.9 1.7 2 0 0 2 2 2 1 Apx/Shroom domain ASD1 TGF_beta PF00019.20 KFQ96402.1 - 2.6e-26 92.6 0.4 6.5e-26 91.3 0.4 1.7 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFQ96402.1 - 0.036 13.8 0.1 0.07 12.9 0.1 1.5 1 1 0 1 1 1 0 TGF-beta propeptide LEAP-2 PF07359.11 KFQ96403.1 - 3.1e-43 145.5 6.9 3.4e-43 145.4 6.9 1.0 1 0 0 1 1 1 1 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) EB PF01683.18 KFQ96403.1 - 0.0021 18.3 0.7 0.0022 18.3 0.7 1.2 1 0 0 1 1 1 1 EB module SIL1 PF16782.5 KFQ96403.1 - 0.17 11.0 0.0 0.2 10.9 0.0 1.0 1 0 0 1 1 1 0 Nucleotide exchange factor SIL1 AF-4 PF05110.13 KFQ96404.1 - 0 1404.3 146.9 0 1404.2 146.9 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Peptidase_S64 PF08192.11 KFQ96404.1 - 0.0008 18.0 21.1 0.0008 18.0 21.1 5.0 3 2 0 4 4 4 1 Peptidase family S64 zf-CCHC_3 PF13917.6 KFQ96405.1 - 1.2e-18 66.8 4.3 2.5e-18 65.7 4.3 1.6 1 0 0 1 1 1 1 Zinc knuckle CLIP1_ZNF PF16641.5 KFQ96405.1 - 0.061 13.2 1.6 0.092 12.7 1.6 1.3 1 0 0 1 1 1 0 CLIP1 zinc knuckle PNISR PF15996.5 KFQ96405.1 - 0.61 10.3 24.6 0.78 10.0 24.6 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Menin PF05053.13 KFQ96405.1 - 2.1 6.6 17.3 2.5 6.3 17.3 1.0 1 0 0 1 1 1 0 Menin V_ATPase_I PF01496.19 KFQ96405.1 - 2.6 5.9 5.5 2.7 5.8 5.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WDCP PF15390.6 KFQ96405.1 - 3.7 5.8 13.5 4.1 5.7 13.5 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Nop14 PF04147.12 KFQ96405.1 - 9.2 4.3 25.0 10 4.2 25.0 1.0 1 0 0 1 1 1 0 Nop14-like family HSP70 PF00012.20 KFQ96406.1 - 2.2e-209 696.6 15.3 3.7e-203 676.0 0.1 3.0 1 1 2 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 KFQ96406.1 - 7.6e-11 41.4 0.0 1.8e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 MreB/Mbl protein Raco_middle PF17651.1 KFQ96406.1 - 0.011 15.4 0.1 5.1 6.8 0.1 2.6 2 0 0 2 2 2 0 RACo middle region Clr5 PF14420.6 KFQ96406.1 - 0.072 13.3 0.2 0.072 13.3 0.2 3.1 4 0 0 4 4 4 0 Clr5 domain DDHD PF02862.17 KFQ96406.1 - 4.8 7.3 10.9 0.17 12.0 3.0 2.2 2 0 0 2 2 2 0 DDHD domain RWD PF05773.22 KFQ96407.1 - 7e-25 87.6 0.0 1.6e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 RWD domain IBR PF01485.21 KFQ96407.1 - 4.2e-18 65.3 20.0 2.2e-14 53.4 2.7 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 KFQ96407.1 - 0.00024 21.0 16.4 0.00024 21.0 16.4 4.3 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFQ96407.1 - 0.011 16.1 13.5 0.011 16.1 13.5 4.6 3 1 1 4 4 4 0 Ring finger domain TBPIP PF07106.13 KFQ96407.1 - 0.083 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain DUF3644 PF12358.8 KFQ96407.1 - 0.12 12.8 0.0 3.2 8.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3644) zf-RING_11 PF17123.5 KFQ96407.1 - 0.38 10.5 11.4 2.9 7.7 11.4 2.7 1 0 0 1 1 1 0 RING-like zinc finger Glucosamine_iso PF01182.20 KFQ96408.1 - 2.6e-13 50.4 0.0 3.9e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF2370 PF10176.9 KFQ96409.1 - 1.4e-10 41.2 3.9 8.9e-08 32.1 0.5 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF2370) Comm PF15957.5 KFQ96409.1 - 0.011 16.1 0.2 0.02 15.2 0.2 1.4 1 0 0 1 1 1 0 Commissureless Herpes_UL56 PF04534.12 KFQ96409.1 - 0.11 11.9 0.8 0.16 11.4 0.8 1.2 1 0 0 1 1 1 0 Herpesvirus UL56 protein WBP-1 PF11669.8 KFQ96409.1 - 0.41 11.3 0.1 0.41 11.3 0.1 2.8 3 1 1 4 4 4 0 WW domain-binding protein 1 Sprouty PF05210.13 KFQ96410.1 - 1.5e-26 92.8 31.8 2.5e-26 92.0 31.8 1.4 1 0 0 1 1 1 1 Sprouty protein (Spry) FGF PF00167.18 KFQ96412.1 - 1.2e-41 141.7 0.0 1.5e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.13 KFQ96412.1 - 0.00075 19.7 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Fascin domain GCR PF02155.15 KFQ96413.1 - 6.2e-181 601.4 3.7 7.7e-181 601.1 3.7 1.1 1 0 0 1 1 1 1 Glucocorticoid receptor Hormone_recep PF00104.30 KFQ96413.1 - 1.3e-29 103.3 5.2 1.3e-29 103.3 5.2 1.6 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFQ96413.1 - 3e-28 98.1 13.0 5.6e-28 97.2 13.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Yip1 PF04893.17 KFQ96414.1 - 1.9e-10 40.7 16.5 2.6e-10 40.3 16.5 1.3 1 0 0 1 1 1 1 Yip1 domain BTB_2 PF02214.22 KFQ96415.1 - 4.7e-16 58.9 0.0 1.1e-15 57.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KFQ96415.1 - 0.0053 16.9 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Dynein_C PF18199.1 KFQ96415.1 - 0.0094 15.2 0.1 0.013 14.7 0.1 1.1 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain PRELI PF04707.14 KFQ96417.1 - 2.7e-38 131.3 0.2 3.3e-38 131.0 0.2 1.1 1 0 0 1 1 1 1 PRELI-like family DnaJ_CXXCXGXG PF00684.19 KFQ96418.1 - 0.017 15.5 9.7 0.05 14.0 9.4 2.0 1 1 0 1 1 1 0 DnaJ central domain FA PF08736.11 KFQ96418.1 - 0.17 12.0 0.1 0.17 12.0 0.1 1.8 2 0 0 2 2 2 0 FERM adjacent (FA) Anti-TRAP PF15777.5 KFQ96418.1 - 0.62 10.1 8.3 11 6.1 8.3 2.5 1 1 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF678 PF05077.12 KFQ96418.1 - 0.84 9.8 4.7 2.3 8.4 4.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF678) SH3_9 PF14604.6 KFQ96419.1 - 7.5e-26 89.8 0.2 4.7e-13 48.8 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 KFQ96419.1 - 1.3e-25 88.8 0.1 2.8e-11 42.9 0.0 2.8 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 KFQ96419.1 - 1.9e-25 88.2 0.0 1.4e-11 43.8 0.0 2.6 2 0 0 2 2 2 2 SH3 domain zf-C3HC4_2 PF13923.6 KFQ96419.1 - 1e-09 38.1 10.9 1.8e-09 37.3 10.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ96419.1 - 1.5e-09 37.6 10.3 2.7e-09 36.7 10.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ96419.1 - 5.1e-09 36.3 9.2 9.3e-09 35.5 9.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFQ96419.1 - 7.2e-09 35.5 8.5 7.2e-09 35.5 8.5 1.8 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFQ96419.1 - 2e-08 34.0 7.1 3.4e-08 33.2 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFQ96419.1 - 1.6e-07 31.1 9.2 2.8e-07 30.4 9.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 KFQ96419.1 - 9.7e-06 25.3 7.9 1.7e-05 24.5 7.9 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KFQ96419.1 - 0.0002 21.4 9.6 0.00039 20.5 9.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFQ96419.1 - 0.002 17.9 9.4 0.009 15.8 9.6 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFQ96419.1 - 0.029 14.7 6.5 0.059 13.7 6.5 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KFQ96419.1 - 0.3 10.8 8.0 0.079 12.7 3.1 2.4 1 1 1 2 2 2 0 RING-like zinc finger zf-Nse PF11789.8 KFQ96419.1 - 1.2 9.1 7.2 2.8 7.8 7.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.20 KFQ96419.1 - 1.4 8.7 8.0 3.3 7.5 8.0 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DUF1272 PF06906.11 KFQ96419.1 - 1.8 8.7 8.1 0.55 10.4 4.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-ANAPC11 PF12861.7 KFQ96419.1 - 2.5 8.2 5.5 5.9 7.0 5.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.7 KFQ96419.1 - 3.3 7.8 9.7 8.8 6.4 9.7 1.7 1 0 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 KFQ96419.1 - 3.8 7.6 9.3 7 6.7 9.3 1.4 1 0 0 1 1 1 0 zinc-ribbons tRNA-synt_1 PF00133.22 KFQ96420.1 - 1.6e-40 139.0 0.0 2.4e-25 88.9 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KFQ96420.1 - 2.6e-18 66.0 0.0 2.3e-09 36.5 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KFQ96420.1 - 3.6e-16 59.5 0.0 1e-15 58.0 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KFQ96420.1 - 1.9e-06 27.5 0.0 3.8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 KFQ96420.1 - 0.028 13.3 0.4 0.1 11.5 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (K) RRM_1 PF00076.22 KFQ96421.1 - 8.4e-10 38.3 0.6 0.00011 21.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFQ96421.1 - 8.4e-09 35.3 0.0 0.00012 22.0 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 KFQ96421.1 - 2e-05 24.5 0.5 0.1 12.6 0.0 3.2 2 2 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PWI PF01480.17 KFQ96421.1 - 0.00013 22.2 0.0 0.00034 20.9 0.0 1.7 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.24 KFQ96421.1 - 0.00014 21.7 1.1 0.00025 20.9 1.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Herpes_UL6 PF01763.16 KFQ96421.1 - 0.098 11.2 6.1 0.18 10.3 6.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like zf_CCCH_4 PF18345.1 KFQ96421.1 - 0.16 12.0 0.6 0.29 11.3 0.6 1.4 1 0 0 1 1 1 0 Zinc finger domain Ly49 PF08391.10 KFQ96421.1 - 0.55 10.6 6.6 2.9 8.3 6.6 2.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region FapA PF03961.13 KFQ96421.1 - 0.91 8.0 11.3 1.7 7.2 11.3 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A WD40 PF00400.32 KFQ96422.1 - 2.2e-10 40.9 2.2 1.1 10.3 0.1 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ96422.1 - 0.00019 21.7 0.1 12 6.3 0.0 4.7 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 KFQ96423.1 - 1e-65 221.7 0.3 1.7e-65 221.0 0.3 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ96423.1 - 5.6e-39 134.0 0.3 7.3e-39 133.6 0.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ96423.1 - 1.1e-13 51.1 0.1 1.6e-13 50.7 0.1 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFQ96423.1 - 0.0018 17.3 0.6 0.0018 17.3 0.6 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KFQ96423.1 - 0.002 17.0 0.4 0.0048 15.7 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFQ96423.1 - 0.0022 18.0 0.1 0.0031 17.5 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DDE_Tnp_4 PF13359.6 KFQ96423.1 - 0.022 14.4 0.3 0.044 13.5 0.3 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease Endonuclease_5 PF04493.14 KFQ96423.1 - 0.075 12.7 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Endonuclease V Amidohydro_1 PF01979.20 KFQ96424.1 - 3.7e-38 131.7 0.1 4.8e-38 131.4 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFQ96424.1 - 2.6e-12 47.0 0.4 5e-07 29.6 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_2 PF04909.14 KFQ96424.1 - 0.00085 19.2 0.0 0.0028 17.5 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase DUF3928 PF13065.6 KFQ96424.1 - 0.028 15.2 0.0 0.055 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3928) DJ-1_PfpI PF01965.24 KFQ96424.1 - 0.17 11.7 0.2 9 6.1 0.2 3.3 2 1 0 2 2 2 0 DJ-1/PfpI family JAKMIP_CC3 PF16034.5 KFQ96425.1 - 4.4e-84 281.4 19.7 4.4e-84 281.4 19.7 6.7 3 2 2 6 6 6 1 JAKMIP CC3 domain Pox_A_type_inc PF04508.12 KFQ96425.1 - 0.018 14.8 0.0 0.018 14.8 0.0 7.8 10 0 0 10 10 10 0 Viral A-type inclusion protein repeat VPS11_C PF12451.8 KFQ96425.1 - 0.47 10.7 0.0 0.47 10.7 0.0 5.4 6 0 0 6 6 6 0 Vacuolar protein sorting protein 11 C terminal GDNF PF02351.16 KFQ96426.1 - 1.8e-41 141.0 42.1 1.3e-23 83.7 8.0 3.1 3 0 0 3 3 3 3 GDNF/GAS1 domain 2-Hacid_dh_C PF02826.19 KFQ96427.1 - 8.8e-57 191.3 0.0 1.2e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFQ96427.1 - 4.5e-27 94.3 0.0 5.5e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFQ96427.1 - 8.5e-05 22.8 0.0 0.00016 21.8 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 KFQ96427.1 - 0.085 13.4 0.0 0.27 11.8 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain C1_2 PF03107.16 KFQ96428.1 - 0.12 12.7 4.9 0.33 11.3 4.9 1.7 1 0 0 1 1 1 0 C1 domain TB2_DP1_HVA22 PF03134.19 KFQ96429.1 - 5.4e-22 77.5 10.0 7.5e-22 77.1 10.0 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family JmjC PF02373.22 KFQ96430.1 - 2.1e-17 63.6 0.0 3e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KFQ96430.1 - 0.0061 16.2 0.1 0.028 14.1 0.0 2.1 2 0 0 2 2 2 1 Cupin domain Steroid_dh PF02544.16 KFQ96431.1 - 1.2e-59 200.6 3.9 1.4e-59 200.4 3.9 1.0 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KFQ96431.1 - 1.7e-06 27.8 0.1 2e-06 27.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KFQ96431.1 - 0.011 16.1 1.6 0.03 14.7 1.6 1.7 1 1 0 1 1 1 0 Phospholipid methyltransferase Memo PF01875.17 KFQ96432.1 - 9.3e-75 251.3 0.0 1.1e-74 251.0 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Glycolytic PF00274.19 KFQ96432.1 - 0.068 11.9 0.1 0.098 11.4 0.1 1.1 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I Dpy-30 PF05186.13 KFQ96433.1 - 3.3e-09 36.3 0.9 3.9e-09 36.1 0.1 1.6 2 0 0 2 2 2 1 Dpy-30 motif AAA PF00004.29 KFQ96434.1 - 1.1e-39 135.9 0.0 2.8e-39 134.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFQ96434.1 - 4.1e-06 26.6 0.0 1.1e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 KFQ96434.1 - 1.2e-05 25.2 0.0 2.8e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 KFQ96434.1 - 6.1e-05 23.3 0.4 0.019 15.2 0.1 3.4 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFQ96434.1 - 0.00014 21.8 0.2 0.0024 17.9 0.2 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KFQ96434.1 - 0.00034 19.9 0.1 0.00095 18.5 0.0 1.6 1 1 1 2 2 2 1 TIP49 P-loop domain TniB PF05621.11 KFQ96434.1 - 0.00057 19.3 1.2 0.4 10.1 0.0 3.4 3 1 1 4 4 4 2 Bacterial TniB protein AAA_2 PF07724.14 KFQ96434.1 - 0.0016 18.6 0.0 0.0043 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 KFQ96434.1 - 0.0024 17.3 0.5 0.008 15.6 0.5 1.9 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KFQ96434.1 - 0.0062 16.9 1.2 0.097 13.0 0.2 3.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 KFQ96434.1 - 0.0079 16.2 0.0 0.045 13.8 0.0 2.2 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 KFQ96434.1 - 0.0083 15.9 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 KFQ96434.1 - 0.011 15.0 0.0 0.044 12.9 0.0 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KFQ96434.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 KFQ96434.1 - 0.025 14.4 0.0 0.06 13.2 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein MIT PF04212.18 KFQ96434.1 - 0.049 13.7 0.1 0.13 12.3 0.1 1.8 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain AAA_18 PF13238.6 KFQ96434.1 - 0.072 13.6 0.0 0.21 12.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 KFQ96434.1 - 0.087 13.0 0.0 0.28 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KFQ96434.1 - 0.13 11.8 0.0 0.93 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Cation_efflux PF01545.21 KFQ96435.1 - 3.7e-32 111.7 14.8 5.9e-32 111.0 14.8 1.3 1 0 0 1 1 1 1 Cation efflux family Peptidase_M28 PF04389.17 KFQ96436.1 - 5e-48 163.4 0.0 6.3e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Get5_C PF18514.1 KFQ96436.1 - 0.16 11.7 0.6 0.36 10.6 0.1 1.9 2 0 0 2 2 2 0 Get5 C-terminal domain Pkinase PF00069.25 KFQ96437.1 - 1.5e-70 237.6 0.0 2.5e-70 236.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ96437.1 - 6.6e-33 114.1 0.0 1e-32 113.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KFQ96437.1 - 3e-28 97.4 18.5 2.9e-14 52.7 3.0 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 KFQ96437.1 - 1.5e-09 38.3 0.6 2.8e-07 31.0 0.1 3.3 2 1 1 3 3 3 1 PH domain Kinase-like PF14531.6 KFQ96437.1 - 1.6e-07 30.9 0.0 3.4e-06 26.6 0.0 2.6 2 1 0 3 3 3 1 Kinase-like C1_2 PF03107.16 KFQ96437.1 - 1.3e-05 25.4 15.0 0.0095 16.2 1.6 2.6 2 0 0 2 2 2 2 C1 domain Kdo PF06293.14 KFQ96437.1 - 1.6e-05 24.4 0.0 3.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_9 PF13901.6 KFQ96437.1 - 0.089 12.8 12.2 1.1 9.2 0.4 2.5 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon RIO1 PF01163.22 KFQ96437.1 - 0.13 11.8 0.2 0.26 10.9 0.2 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KFQ96437.1 - 0.13 12.2 0.0 1.3 8.9 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KFQ96437.1 - 0.13 11.2 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PHD PF00628.29 KFQ96437.1 - 0.15 12.0 16.1 1.5 8.7 3.2 2.6 2 0 0 2 2 2 0 PHD-finger FYVE_2 PF02318.16 KFQ96437.1 - 1.7 8.8 10.9 7.3 6.8 5.6 2.6 2 0 0 2 2 2 0 FYVE-type zinc finger PHD_2 PF13831.6 KFQ96437.1 - 3.6 7.2 7.4 13 5.4 0.7 2.9 2 0 0 2 2 2 0 PHD-finger Methyltransf_28 PF02636.17 KFQ96438.1 - 3.1e-75 253.2 0.0 4.2e-75 252.8 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CBF PF03914.17 KFQ96439.1 - 4.3e-56 189.6 4.5 4.5e-56 189.5 0.5 2.9 2 0 0 2 2 2 1 CBF/Mak21 family Cnd1 PF12717.7 KFQ96439.1 - 0.014 15.5 1.2 0.014 15.5 1.2 1.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF2553 PF10830.8 KFQ96439.1 - 0.85 10.5 5.3 0.6 11.0 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2553) Sulfotransfer_1 PF00685.27 KFQ96440.1 - 2e-36 125.8 0.1 2.4e-36 125.6 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFQ96440.1 - 0.00012 22.6 0.0 0.00016 22.1 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family DUF1266 PF06889.11 KFQ96440.1 - 0.12 12.4 2.4 0.18 11.8 2.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1266) HU-CCDC81_euk_2 PF18289.1 KFQ96441.1 - 7.1e-21 74.2 0.1 8e-21 74.0 0.1 1.1 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 RVT_1 PF00078.27 KFQ96443.1 - 0.00031 20.3 0.0 0.0021 17.6 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PDEase_I PF00233.19 KFQ96444.1 - 1.6e-83 280.1 4.6 1.6e-83 280.1 4.6 1.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.12 KFQ96444.1 - 1e-31 108.6 0.1 2.9e-31 107.1 0.1 1.9 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal TEX19 PF15553.6 KFQ96444.1 - 0.46 10.4 3.5 1 9.3 3.5 1.7 1 0 0 1 1 1 0 Testis-expressed protein 19 LSM PF01423.22 KFQ96446.1 - 8.4e-21 73.4 0.6 9.2e-21 73.3 0.6 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFQ96446.1 - 0.078 13.1 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.7 KFQ96446.1 - 0.089 12.9 0.1 0.15 12.2 0.1 1.4 1 1 0 1 1 1 0 Scd6-like Sm domain Avl9 PF09794.9 KFQ96447.1 - 4e-146 486.5 0.0 5e-146 486.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 KFQ96447.1 - 6.3e-12 45.7 2.0 6.3e-07 29.3 0.0 3.2 2 1 1 3 3 3 3 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 KFQ96447.1 - 9.9e-09 35.2 0.0 0.00011 22.1 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DENN PF02141.21 KFQ96447.1 - 0.00013 21.9 0.9 0.27 11.2 0.4 2.6 3 0 0 3 3 3 2 DENN (AEX-3) domain Peptidase_C93 PF06035.11 KFQ96447.1 - 0.02 14.7 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial transglutaminase-like cysteine proteinase BTLCP Afi1 PF07792.12 KFQ96447.1 - 0.14 12.7 0.0 0.4 11.1 0.0 1.8 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking BACK PF07707.15 KFQ96448.1 - 1.4e-20 73.3 1.5 2.6e-20 72.5 1.5 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFQ96448.1 - 1.5e-18 66.3 1.9 0.00011 22.4 0.0 4.7 4 1 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 KFQ96448.1 - 5.7e-18 64.2 23.5 1.4e-09 37.4 0.1 7.3 5 3 1 6 6 6 3 Kelch motif Kelch_2 PF07646.15 KFQ96448.1 - 6.5e-09 35.4 5.1 0.037 14.0 0.0 5.2 4 1 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 KFQ96448.1 - 4.6e-06 26.5 11.2 0.05 13.6 0.0 5.3 4 1 1 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KFQ96448.1 - 5.6e-05 23.3 5.0 0.25 11.7 0.1 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain baeRF_family5 PF18846.1 KFQ96448.1 - 0.11 12.7 0.3 1.7 8.9 0.0 2.8 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 5 Kelch_5 PF13854.6 KFQ96448.1 - 0.17 11.9 4.4 7.3 6.7 0.1 3.8 4 0 0 4 4 4 0 Kelch motif WYL_2 PF10902.8 KFQ96448.1 - 0.24 11.8 2.7 23 5.4 0.0 3.6 4 0 0 4 4 4 0 WYL_2, Sm-like SH3 beta-barrel fold CENP-B_dimeris PF09026.10 KFQ96449.1 - 0.45 10.9 10.6 0.26 11.7 7.5 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Chromadorea_ALT PF05535.12 KFQ96449.1 - 0.55 10.5 2.6 0.51 10.6 0.2 2.2 2 0 0 2 2 2 0 Chromadorea ALT protein DUF3727 PF12527.8 KFQ96449.1 - 5.1 7.4 7.8 2 8.7 3.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3727) zf-CCHC_6 PF15288.6 KFQ96450.1 - 0.009 15.8 0.7 0.021 14.6 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle RXT2_N PF08595.11 KFQ96450.1 - 0.27 11.3 8.5 0.36 10.9 8.5 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal TFIIF_alpha PF05793.12 KFQ96450.1 - 0.42 9.1 13.3 0.49 8.9 13.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PBP1_TM PF14812.6 KFQ96450.1 - 2.8 8.4 11.6 4.6 7.7 11.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FKBP_C PF00254.28 KFQ96451.1 - 5.2e-113 369.7 0.0 1.5e-26 92.5 0.0 5.1 5 0 0 5 5 5 4 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_1 PF00036.32 KFQ96451.1 - 9.4e-10 37.3 0.4 0.00049 19.5 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFQ96451.1 - 5.5e-06 26.7 1.0 0.015 15.7 0.1 2.3 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFQ96451.1 - 1.1e-05 24.7 0.3 0.097 12.2 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFQ96451.1 - 1.6e-05 24.4 0.3 0.12 12.4 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KFQ96451.1 - 0.00027 20.7 0.1 0.95 9.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair DUF2895 PF11444.8 KFQ96451.1 - 0.011 15.1 0.0 4.4 6.6 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2895) DUF3047 PF11249.8 KFQ96451.1 - 0.11 11.9 0.0 3.2 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3047) UMPH-1 PF05822.12 KFQ96452.1 - 5.5e-121 402.7 6.0 6.3e-121 402.5 6.0 1.0 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 KFQ96452.1 - 0.00012 22.5 0.1 0.00026 21.5 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ACT_7 PF13840.6 KFQ96452.1 - 0.0013 18.5 0.4 5.1 7.0 0.1 3.3 3 0 0 3 3 3 2 ACT domain CIDE-N PF02017.15 KFQ96452.1 - 0.012 15.7 0.1 0.28 11.2 0.0 2.6 2 0 0 2 2 2 0 CIDE-N domain NIF PF03031.18 KFQ96452.1 - 0.021 14.6 0.2 1.4 8.7 0.0 2.7 1 1 1 2 2 2 0 NLI interacting factor-like phosphatase PHTB1_N PF14727.6 KFQ96453.1 - 2.3e-168 560.8 0.0 3.1e-168 560.4 0.0 1.2 1 0 0 1 1 1 1 PTHB1 N-terminus PHTB1_C PF14728.6 KFQ96453.1 - 5.8e-156 519.3 4.1 7.6e-156 518.9 4.1 1.1 1 0 0 1 1 1 1 PTHB1 C-terminus DUF166 PF02593.14 KFQ96453.1 - 0.069 12.7 0.8 0.14 11.7 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function VWD PF00094.25 KFQ96454.1 - 9.4e-37 126.7 0.1 2.3e-36 125.4 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type D domain VWC PF00093.18 KFQ96454.1 - 4.3e-22 78.2 149.0 5.6e-09 36.2 16.3 8.0 6 1 0 6 6 6 5 von Willebrand factor type C domain C8 PF08742.11 KFQ96454.1 - 5.7e-15 55.5 14.8 5.7e-15 55.5 14.8 5.0 4 2 2 6 6 6 1 C8 domain TIL PF01826.17 KFQ96454.1 - 1.5e-10 41.2 14.3 1.5e-10 41.2 14.3 9.2 3 1 3 6 6 6 1 Trypsin Inhibitor like cysteine rich domain TILa PF12714.7 KFQ96454.1 - 0.0039 17.1 12.4 0.0039 17.1 12.4 9.1 6 3 3 9 9 9 3 TILa domain 7tm_1 PF00001.21 KFQ96455.1 - 5e-43 147.3 13.9 6.3e-43 147.0 13.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) T-box PF00907.22 KFQ96456.1 - 2e-55 187.9 0.1 2.2e-55 187.8 0.1 1.0 1 0 0 1 1 1 1 T-box ubiquitin PF00240.23 KFQ96457.1 - 2.7e-08 33.4 0.1 4.1e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KFQ96457.1 - 0.0012 19.4 0.0 0.0022 18.5 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KFQ96457.1 - 0.19 11.8 0.0 0.47 10.6 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Septin PF00735.18 KFQ96458.1 - 6.9e-124 412.7 0.2 7.9e-124 412.5 0.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFQ96458.1 - 2e-07 31.1 0.0 4.2e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFQ96458.1 - 4.8e-07 29.8 3.6 0.00014 21.8 0.4 2.4 2 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KFQ96458.1 - 0.00014 21.3 1.2 0.039 13.3 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AIG1 PF04548.16 KFQ96458.1 - 0.00018 20.9 0.1 0.00053 19.4 0.0 1.8 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.27 KFQ96458.1 - 0.00053 19.6 0.6 0.33 10.5 0.1 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KFQ96458.1 - 0.0051 17.3 0.0 0.014 15.9 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 KFQ96458.1 - 0.0059 16.9 0.0 0.02 15.2 0.0 1.9 1 1 1 2 2 2 1 AAA domain Dynamin_N PF00350.23 KFQ96458.1 - 0.0061 16.6 4.2 0.43 10.6 0.3 3.0 2 1 1 3 3 3 1 Dynamin family AAA_16 PF13191.6 KFQ96458.1 - 0.007 16.8 0.0 0.016 15.6 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain Ras PF00071.22 KFQ96458.1 - 0.0074 15.9 0.1 0.022 14.4 0.0 1.8 2 0 0 2 2 2 1 Ras family G-alpha PF00503.20 KFQ96458.1 - 0.0075 15.5 0.6 4.2 6.4 0.1 2.7 2 1 1 3 3 3 2 G-protein alpha subunit FeoB_N PF02421.18 KFQ96458.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.6 KFQ96458.1 - 0.028 14.1 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KFQ96458.1 - 0.035 13.6 0.1 0.083 12.4 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region HEPPP_synt_1 PF07307.11 KFQ96458.1 - 0.049 13.2 0.3 0.079 12.5 0.3 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Roc PF08477.13 KFQ96458.1 - 0.056 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 KFQ96458.1 - 0.092 12.8 0.1 12 5.9 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain NB-ARC PF00931.22 KFQ96458.1 - 0.15 11.2 1.0 0.34 10.1 0.0 2.0 2 1 0 2 2 2 0 NB-ARC domain DUF1542 PF07564.11 KFQ96458.1 - 0.32 11.1 3.0 1 9.5 3.0 1.8 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1542) HHH_3 PF12836.7 KFQ96459.1 - 6.2e-42 141.7 0.2 1.3e-20 73.4 0.1 2.3 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH PF00633.23 KFQ96459.1 - 4.3e-17 61.0 0.1 1.3e-06 27.9 0.0 3.7 3 0 0 3 3 3 3 Helix-hairpin-helix motif HHH_6 PF14579.6 KFQ96459.1 - 8.2e-09 35.6 0.0 6.1e-05 23.2 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix motif T2SSK PF03934.13 KFQ96459.1 - 4e-08 33.0 0.0 0.0023 17.4 0.0 2.2 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein K Exo_endo_phos PF03372.23 KFQ96459.1 - 1.1e-07 31.6 0.0 3.1e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HHH_2 PF12826.7 KFQ96459.1 - 1.4e-07 31.5 0.1 0.022 14.8 0.0 2.9 3 0 0 3 3 3 2 Helix-hairpin-helix motif HHH_5 PF14520.6 KFQ96459.1 - 1.4e-05 25.6 0.2 1.2 9.9 0.1 4.0 3 2 2 5 5 5 4 Helix-hairpin-helix domain PsbU PF06514.11 KFQ96459.1 - 0.0064 16.5 0.0 0.69 9.9 0.0 2.4 2 0 0 2 2 2 1 Photosystem II 12 kDa extrinsic protein (PsbU) Exo_endo_phos_2 PF14529.6 KFQ96459.1 - 0.043 13.7 0.4 0.13 12.1 0.4 1.9 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase DUF1704 PF08014.11 KFQ96460.1 - 8.4e-16 57.9 0.0 1.2e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1704) Anillin PF08174.11 KFQ96461.1 - 2.2e-37 128.6 0.1 7.6e-37 126.9 0.1 2.0 1 0 0 1 1 1 1 Cell division protein anillin Anillin_N PF16018.5 KFQ96461.1 - 2.3e-37 127.4 8.2 8e-34 116.1 0.9 4.7 5 0 0 5 5 5 2 Anillin N-terminus PH PF00169.29 KFQ96461.1 - 7.8e-18 64.9 1.4 1.6e-17 63.9 0.2 2.3 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KFQ96461.1 - 0.018 15.4 0.1 0.077 13.4 0.1 2.2 1 0 0 1 1 1 0 Pleckstrin homology domain Lipase_GDSL PF00657.22 KFQ96462.1 - 1.3e-12 48.1 0.0 2.2e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SapB_2 PF03489.17 KFQ96462.1 - 0.031 14.4 0.1 0.092 12.9 0.1 1.8 1 0 0 1 1 1 0 Saposin-like type B, region 2 Cu-binding_MopE PF11617.8 KFQ96462.1 - 1.3 9.2 10.8 0.044 13.9 3.3 2.4 2 1 0 2 2 2 0 Putative metal-binding motif DUF3361 PF11841.8 KFQ96463.1 - 6.3e-62 208.1 3.5 1.4e-61 207.0 3.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.13 KFQ96463.1 - 4.5e-42 144.1 0.9 9.2e-42 143.1 0.9 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 KFQ96463.1 - 7.8e-39 133.3 0.1 3.2e-38 131.3 0.0 2.2 3 0 0 3 3 3 1 Pleckstrin homology domain ZFYVE21_C PF16696.5 KFQ96463.1 - 0.067 13.1 0.1 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 Zinc finger FYVE domain-containing protein 21 C-terminus FERM_N PF09379.10 KFQ96463.1 - 0.079 12.9 0.0 0.71 9.9 0.0 2.5 3 0 0 3 3 3 0 FERM N-terminal domain 7tm_1 PF00001.21 KFQ96464.1 - 3.2e-08 33.2 27.2 5.6e-08 32.4 27.2 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PepSY_TM PF03929.16 KFQ96464.1 - 9 5.9 11.1 2.2 7.9 0.1 2.1 1 1 1 2 2 2 0 PepSY-associated TM region Thioredoxin PF00085.20 KFQ96465.1 - 8.8e-05 22.4 0.1 0.00012 22.1 0.1 1.3 1 1 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 KFQ96465.1 - 0.00034 20.4 0.0 0.00034 20.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KFQ96465.1 - 0.0011 18.9 0.0 0.0011 18.8 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Glutaredoxin PF00462.24 KFQ96465.1 - 0.0076 16.4 0.0 0.0092 16.2 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin Fz PF01392.22 KFQ96466.1 - 1.1e-28 100.1 2.7 1.1e-28 100.1 2.7 1.8 2 1 0 2 2 2 1 Fz domain NTR PF01759.21 KFQ96466.1 - 9e-15 54.4 0.9 1.2e-14 54.0 0.3 1.5 1 1 0 1 1 1 1 UNC-6/NTR/C345C module Ependymin PF00811.18 KFQ96467.1 - 3.6e-37 127.5 0.3 4e-37 127.3 0.3 1.0 1 0 0 1 1 1 1 Ependymin MENTAL PF10457.9 KFQ96468.1 - 9.7e-64 214.4 5.1 1.2e-63 214.2 5.1 1.1 1 0 0 1 1 1 1 Cholesterol-capturing domain Mlh1_C PF16413.5 KFQ96469.1 - 1.4e-98 329.5 0.4 2.2e-98 329.0 0.4 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KFQ96469.1 - 3.7e-34 117.0 0.2 6.8e-34 116.1 0.2 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KFQ96469.1 - 7.6e-14 51.7 0.1 1.6e-13 50.7 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KFQ96469.1 - 4.4e-08 33.6 0.1 1.1e-07 32.3 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CAF1 PF04857.20 KFQ96469.1 - 0.027 13.7 0.2 0.59 9.2 0.0 2.2 1 1 1 2 2 2 0 CAF1 family ribonuclease Hfx_Cass5 PF18287.1 KFQ96469.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Integron Cassette Protein Hfx_Cass5 TPR_2 PF07719.17 KFQ96470.1 - 0.00076 19.4 0.0 2.2 8.6 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ96470.1 - 0.006 16.4 0.0 0.7 9.8 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF3856 PF12968.7 KFQ96470.1 - 0.11 12.5 0.1 5.2 7.1 0.1 2.5 2 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_6 PF13174.6 KFQ96470.1 - 0.16 12.7 0.1 11 6.9 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat UvrD_C PF13361.6 KFQ96471.1 - 4.9e-08 32.7 0.0 0.0005 19.6 0.0 4.7 3 2 1 4 4 4 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 KFQ96471.1 - 2.7e-06 27.1 0.0 0.1 12.4 0.0 2.6 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Ank_2 PF12796.7 KFQ96471.1 - 5.6e-06 26.9 0.0 1.8e-05 25.2 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) UvrD-helicase PF00580.21 KFQ96471.1 - 1e-05 25.3 1.8 1e-05 25.3 1.8 4.1 4 2 0 4 4 4 1 UvrD/REP helicase N-terminal domain Clathrin PF00637.20 KFQ96471.1 - 0.0001 22.2 13.7 0.057 13.3 2.7 4.5 4 1 1 5 5 5 2 Region in Clathrin and VPS Ank_4 PF13637.6 KFQ96471.1 - 0.0003 21.3 0.1 0.09 13.4 0.0 3.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) AAA_19 PF13245.6 KFQ96471.1 - 0.0041 17.5 0.1 0.9 9.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KFQ96471.1 - 0.081 13.4 0.0 0.48 10.9 0.0 2.4 1 0 0 1 1 1 0 ABC transporter Ank PF00023.30 KFQ96471.1 - 0.093 13.2 0.0 2.2 8.9 0.0 3.2 4 0 0 4 4 4 0 Ankyrin repeat TPR_1 PF00515.28 KFQ96471.1 - 5.6 7.0 8.3 14 5.7 0.7 4.2 2 1 2 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 KFQ96472.1 - 7.9e-82 274.6 0.0 9.4e-82 274.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ96472.1 - 2.2e-37 128.8 0.0 2.8e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ96472.1 - 0.0011 18.3 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFQ96472.1 - 0.0036 16.1 0.0 0.0056 15.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFQ96472.1 - 0.0055 16.1 0.0 0.0098 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KFQ96472.1 - 0.034 13.7 4.3 0.056 13.0 0.1 2.6 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL APH PF01636.23 KFQ96472.1 - 0.082 12.8 0.1 0.39 10.6 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family STAC2_u1 PF16664.5 KFQ96473.1 - 2.1e-29 102.6 0.1 2.1e-29 102.6 0.1 2.9 2 1 1 3 3 3 1 Unstructured on SH3 and cysteine-rich domain-containing protein 2 SH3_9 PF14604.6 KFQ96473.1 - 3e-19 68.6 0.0 1.3e-15 56.9 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KFQ96473.1 - 7.5e-17 60.7 0.5 1e-14 53.8 0.1 2.3 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFQ96473.1 - 7.3e-16 57.6 0.1 4.8e-07 29.3 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.22 KFQ96473.1 - 2.1e-10 40.3 10.6 5.2e-10 39.1 10.6 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_9 PF13901.6 KFQ96473.1 - 0.00088 19.3 2.6 0.0016 18.5 2.6 1.4 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon C1_2 PF03107.16 KFQ96473.1 - 0.016 15.5 3.2 0.016 15.5 3.2 2.0 2 0 0 2 2 2 0 C1 domain RNA_POL_M_15KD PF02150.16 KFQ96473.1 - 0.091 12.6 1.3 0.19 11.6 1.3 1.5 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit PHD PF00628.29 KFQ96473.1 - 0.096 12.6 8.2 0.21 11.5 8.2 1.6 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 KFQ96473.1 - 0.49 10.5 6.8 0.21 11.7 4.0 1.8 2 0 0 2 2 2 0 KIAA1045 RING finger zf-RING-like PF08746.11 KFQ96473.1 - 2.1 8.8 10.4 5.3 7.4 10.4 1.7 1 0 0 1 1 1 0 RING-like domain Ndc1_Nup PF09531.10 KFQ96473.1 - 4.9 5.7 6.3 7 5.2 6.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup R3H PF01424.22 KFQ96474.1 - 3e-12 46.3 0.6 9.1e-12 44.8 0.1 2.2 2 0 0 2 2 2 1 R3H domain BRO1 PF03097.18 KFQ96475.1 - 5.8e-101 338.1 3.6 5.8e-101 338.1 3.6 2.2 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KFQ96475.1 - 2.8e-93 312.5 18.0 2.8e-93 312.5 18.0 2.1 2 1 0 2 2 2 1 ALIX V-shaped domain binding to HIV Importin_rep_6 PF18829.1 KFQ96475.1 - 0.11 12.7 3.4 0.15 12.2 0.2 2.6 2 0 0 2 2 2 0 Importin repeat 6 DUF3510 PF12022.8 KFQ96475.1 - 0.16 12.4 4.7 7.8 6.9 2.5 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3510) T2SSM PF04612.12 KFQ96475.1 - 0.97 9.5 6.4 3.5 7.6 0.3 2.6 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M Med10 PF09748.9 KFQ96475.1 - 1.1 9.3 6.1 0.24 11.4 1.1 2.5 3 0 0 3 3 3 0 Transcription factor subunit Med10 of Mediator complex DUF592 PF04574.13 KFQ96475.1 - 1.6 8.5 8.2 5.5 6.8 0.1 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF592) DUF2408 PF10303.9 KFQ96475.1 - 2.7 8.5 11.8 0.25 11.9 3.4 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2408) Ly49 PF08391.10 KFQ96475.1 - 3.8 7.9 12.7 0.42 11.0 5.6 2.7 3 0 0 3 3 3 0 Ly49-like protein, N-terminal region CLASP_N PF12348.8 KFQ96476.1 - 2e-52 178.0 4.2 2.7e-36 125.2 0.1 4.3 4 0 0 4 4 4 3 CLASP N terminal HEAT PF02985.22 KFQ96476.1 - 6e-15 54.1 11.8 0.0041 17.3 0.0 9.8 10 0 0 10 10 8 3 HEAT repeat HEAT_2 PF13646.6 KFQ96476.1 - 4.1e-09 36.7 2.0 0.86 10.0 0.3 8.0 6 3 5 11 11 11 2 HEAT repeats HEAT_EZ PF13513.6 KFQ96476.1 - 4.1e-09 36.7 1.8 0.046 14.2 0.0 6.1 6 0 0 6 6 6 2 HEAT-like repeat Cnd1 PF12717.7 KFQ96476.1 - 8.5e-09 35.6 10.4 0.0096 16.0 0.5 6.5 6 2 1 8 8 8 3 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 KFQ96476.1 - 1.6e-07 31.5 3.3 0.017 15.3 0.1 3.9 3 1 1 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KFQ96476.1 - 4.2e-06 25.6 4.9 0.34 9.4 0.1 6.0 5 1 0 6 6 6 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 KFQ96476.1 - 5.6e-05 23.6 2.9 25 5.5 0.0 6.1 6 1 1 7 7 6 0 Vacuolar 14 Fab1-binding region Sec7_N PF12783.7 KFQ96476.1 - 0.00012 22.0 4.8 3 7.7 1.3 4.6 5 0 0 5 5 5 2 Guanine nucleotide exchange factor in Golgi transport N-terminal ParcG PF10274.9 KFQ96476.1 - 0.00033 20.8 3.5 0.0026 17.9 0.1 3.4 3 1 1 4 4 4 1 Parkin co-regulated protein TFCD_C PF12612.8 KFQ96476.1 - 0.00074 19.4 0.4 0.1 12.4 0.1 4.2 5 0 0 5 5 5 1 Tubulin folding cofactor D C terminal MMS19_N PF14500.6 KFQ96476.1 - 0.0011 18.6 4.7 4.4 6.8 0.1 3.7 3 0 0 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 KFQ96476.1 - 0.02 14.0 7.6 1.1 8.3 0.1 3.6 4 0 0 4 4 4 0 RNAPII transcription regulator C-terminal Ipi1_N PF12333.8 KFQ96476.1 - 0.037 14.6 2.4 0.43 11.2 0.0 3.5 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation TAN PF11640.8 KFQ96476.1 - 0.11 12.6 5.8 0.14 12.3 0.1 3.8 3 1 1 4 4 3 0 Telomere-length maintenance and DNA damage repair CP2 PF04516.15 KFQ96477.1 - 1.7e-58 197.6 0.0 2.5e-58 197.1 0.0 1.1 1 0 0 1 1 1 1 CP2 transcription factor SAM_3 PF18016.1 KFQ96477.1 - 1.1e-20 73.1 0.0 1.9e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFQ96477.1 - 0.0081 16.1 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_1 PF00536.30 KFQ96477.1 - 0.052 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFQ96477.1 - 0.12 12.4 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) LRR_6 PF13516.6 KFQ96478.1 - 9.1e-21 72.1 35.1 6.5e-05 22.7 0.1 10.4 11 0 0 11 11 11 5 Leucine Rich repeat LRR_4 PF12799.7 KFQ96478.1 - 5.5e-15 55.2 23.0 0.028 14.8 0.8 7.2 4 1 4 9 9 9 8 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KFQ96478.1 - 3.6e-08 33.2 0.6 1.4e-07 31.2 0.6 2.1 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 KFQ96478.1 - 2.3e-05 24.3 36.2 0.22 12.2 0.1 10.7 10 1 0 10 10 10 2 Leucine Rich Repeat F-box PF00646.33 KFQ96478.1 - 3.9e-05 23.4 1.4 0.00013 21.7 0.3 2.6 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.6 KFQ96478.1 - 0.0021 17.8 18.0 0.53 10.1 2.5 6.2 5 3 1 6 6 6 2 Leucine rich repeat Mating_N PF12731.7 KFQ96478.1 - 0.049 13.7 0.1 1.5 8.9 0.1 2.6 1 1 0 2 2 2 0 Mating-type protein beta 1 PTE PF02126.18 KFQ96478.1 - 0.075 12.4 0.0 11 5.4 0.0 2.5 2 1 0 2 2 2 0 Phosphotriesterase family Xlink PF00193.17 KFQ96479.1 - 1.9e-14 53.8 0.2 1.9e-14 53.8 0.2 2.0 2 0 0 2 2 2 1 Extracellular link domain Sushi PF00084.20 KFQ96479.1 - 0.00021 21.8 0.7 0.00021 21.8 0.7 2.2 2 0 0 2 2 2 1 Sushi repeat (SCR repeat) GAPT PF11770.8 KFQ96479.1 - 0.0062 16.4 0.1 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 GRB2-binding adapter (GAPT) SIT PF15330.6 KFQ96479.1 - 0.01 16.3 1.8 0.018 15.5 0.2 2.2 2 1 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Insulin_TMD PF17870.1 KFQ96479.1 - 0.042 13.9 0.8 0.096 12.8 0.8 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment EphA2_TM PF14575.6 KFQ96479.1 - 0.066 14.1 0.3 0.2 12.6 0.3 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Ly49 PF08391.10 KFQ96479.1 - 0.088 13.2 0.3 0.2 12.0 0.3 1.6 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF4366 PF14283.6 KFQ96479.1 - 0.11 12.6 3.1 0.11 12.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF5383 PF17355.2 KFQ96479.1 - 0.41 11.0 3.3 9.8 6.6 3.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5383) Metallophos PF00149.28 KFQ96481.1 - 3.7e-14 53.7 0.1 4.9e-14 53.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFQ96481.1 - 1e-05 25.8 0.0 2.2e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_35 PF01301.19 KFQ96482.1 - 5.1e-119 397.6 0.0 6.3e-119 397.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 KFQ96482.1 - 1.7e-14 53.9 0.0 1.7e-12 47.4 0.0 2.1 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 KFQ96482.1 - 8.5e-07 29.6 1.2 1.9e-05 25.2 0.0 3.2 3 1 1 4 4 4 1 Beta-galactosidase jelly roll domain 7tm_1 PF00001.21 KFQ96483.1 - 1e-54 185.7 23.1 1.4e-54 185.2 23.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ96483.1 - 4e-10 39.5 24.2 5.9e-10 38.9 24.2 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF621 PF04789.15 KFQ96483.1 - 1.1 8.3 25.5 1.9 7.6 25.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF621) 7tm_1 PF00001.21 KFQ96484.1 - 8e-53 179.4 21.4 1e-52 179.1 21.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ96484.1 - 2.4e-09 37.0 19.9 3.2e-09 36.5 19.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Mito_carr PF00153.27 KFQ96485.1 - 1e-57 192.1 8.8 4.1e-20 71.5 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein TRAPP PF04051.16 KFQ96485.1 - 0.02 14.6 0.0 6.5 6.5 0.0 2.3 2 0 0 2 2 2 0 Transport protein particle (TRAPP) component 40S_SA_C PF16122.5 KFQ96486.1 - 9.3e-28 97.4 21.6 1.6e-27 96.7 21.6 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Ribosomal_S2 PF00318.20 KFQ96486.1 - 1.5e-26 93.0 0.0 1.6e-13 50.4 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 TMC PF07810.13 KFQ96487.1 - 1.6e-36 125.3 3.3 2e-36 124.9 1.2 2.3 2 0 0 2 2 2 1 TMC domain Speriolin_N PF15058.6 KFQ96487.1 - 0.0016 18.5 0.1 0.0028 17.8 0.1 1.3 1 0 0 1 1 1 1 Speriolin N terminus Ctr PF04145.15 KFQ96487.1 - 0.0037 17.9 6.3 4.2 8.0 0.0 4.9 4 2 0 4 4 4 2 Ctr copper transporter family TRAP_beta PF05753.14 KFQ96487.1 - 0.082 12.3 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Translocon-associated protein beta (TRAPB) COX16 PF14138.6 KFQ96487.1 - 0.35 11.4 0.1 0.35 11.4 0.1 3.1 3 1 0 3 3 3 0 Cytochrome c oxidase assembly protein COX16 SieB PF14163.6 KFQ96487.1 - 0.65 9.5 4.5 21 4.6 0.0 3.6 4 0 0 4 4 4 0 Super-infection exclusion protein B SpoIIIAH PF12685.7 KFQ96487.1 - 1.2 9.0 21.5 0.29 11.0 0.1 2.4 2 0 0 2 2 2 0 SpoIIIAH-like protein Zip PF02535.22 KFQ96487.1 - 2.2 7.4 5.6 1.2e+02 1.8 6.4 2.8 3 0 0 3 3 3 0 ZIP Zinc transporter FYVE_2 PF02318.16 KFQ96488.1 - 2e-24 86.1 20.5 2.2e-24 86.0 20.5 1.0 1 0 0 1 1 1 1 FYVE-type zinc finger zf-piccolo PF05715.13 KFQ96488.1 - 0.052 13.7 11.5 0.052 13.7 11.5 2.1 1 1 0 2 2 2 0 Piccolo Zn-finger Siva PF05458.12 KFQ96488.1 - 0.87 9.3 15.6 0.97 9.1 15.6 1.0 1 0 0 1 1 1 0 Cd27 binding protein (Siva) C1_1 PF00130.22 KFQ96488.1 - 4.9 7.1 22.7 1.9 8.5 16.1 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rab_eff_C PF04698.12 KFQ96489.1 - 0 1293.4 25.5 0 1293.2 25.5 1.0 1 0 0 1 1 1 1 Rab effector MyRIP/melanophilin C-terminus SUI1 PF01253.22 KFQ96490.1 - 2.8e-29 101.4 1.0 3.4e-29 101.2 1.0 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF2729 PF10870.8 KFQ96490.1 - 0.38 10.6 4.1 1.3 9.0 4.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2729) Gastrin PF00918.17 KFQ96491.1 - 7.2e-52 175.6 0.0 8e-52 175.5 0.0 1.0 1 0 0 1 1 1 1 Gastrin/cholecystokinin family HAP1_N PF04849.13 KFQ96492.1 - 1.7e-136 454.4 38.4 2.3e-136 454.0 38.4 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Milton PF12448.8 KFQ96492.1 - 4.5e-66 222.3 7.7 4.5e-66 222.3 7.7 2.7 3 0 0 3 3 3 1 Kinesin associated protein KASH_CCD PF14662.6 KFQ96492.1 - 0.0047 16.8 39.2 0.0077 16.1 12.3 3.4 1 1 2 3 3 3 2 Coiled-coil region of CCDC155 or KASH BSD PF03909.17 KFQ96492.1 - 0.42 10.7 2.0 4.5 7.4 0.1 3.1 2 0 0 2 2 2 0 BSD domain Mod_r PF07200.13 KFQ96492.1 - 0.67 10.0 32.9 0.67 10.0 10.1 3.6 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF1664 PF07889.12 KFQ96492.1 - 0.81 9.7 15.4 0.23 11.5 1.2 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Rootletin PF15035.6 KFQ96492.1 - 2.1 8.4 39.3 0.24 11.4 8.0 3.3 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion ATG16 PF08614.11 KFQ96492.1 - 2.8 8.1 37.5 4.5 7.4 22.9 2.8 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) YabA PF06156.13 KFQ96492.1 - 4.3 8.0 30.8 4.7 7.9 3.2 4.5 2 1 2 4 4 4 0 Initiation control protein YabA CorA PF01544.18 KFQ96492.1 - 7.4 5.8 18.4 0.98 8.7 8.6 2.8 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein Atg14 PF10186.9 KFQ96492.1 - 8.1 5.4 24.6 7.3 5.6 4.0 2.7 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Arm PF00514.23 KFQ96494.1 - 2e-44 148.3 18.6 9e-08 31.9 0.1 12.3 13 0 0 13 13 13 7 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KFQ96494.1 - 1.4e-08 34.9 1.4 0.0058 16.7 0.3 4.4 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFQ96494.1 - 6.2e-07 29.2 2.1 12 6.5 0.0 6.0 5 0 0 5 5 5 1 HEAT repeat Adaptin_N PF01602.20 KFQ96494.1 - 1.5e-06 27.1 2.1 0.00085 18.0 1.1 3.2 3 0 0 3 3 3 2 Adaptin N terminal region HEAT_2 PF13646.6 KFQ96494.1 - 1.5e-06 28.5 6.6 0.029 14.8 0.4 5.1 4 1 1 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 KFQ96494.1 - 1.7e-05 25.2 8.2 0.64 10.6 0.3 6.3 4 2 2 6 6 6 2 HEAT-like repeat KAP PF05804.12 KFQ96494.1 - 0.00013 20.3 1.4 0.033 12.3 0.0 3.4 1 1 1 3 3 3 1 Kinesin-associated protein (KAP) DUF3361 PF11841.8 KFQ96494.1 - 0.00056 19.9 2.3 1.7 8.6 0.0 4.7 2 1 1 4 4 4 1 Domain of unknown function (DUF3361) Atx10homo_assoc PF09759.9 KFQ96494.1 - 0.0016 18.4 2.0 0.018 15.0 0.2 3.5 3 2 1 4 4 4 1 Spinocerebellar ataxia type 10 protein domain RasGEF_N_2 PF14663.6 KFQ96494.1 - 0.005 17.2 6.8 6.2 7.3 0.0 5.0 5 2 1 6 6 5 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arm_2 PF04826.13 KFQ96494.1 - 0.013 15.0 3.8 0.61 9.5 0.0 3.6 2 1 1 3 3 3 0 Armadillo-like Queuosine_synth PF02547.15 KFQ96494.1 - 0.017 14.2 0.5 0.037 13.1 0.1 1.7 2 0 0 2 2 2 0 Queuosine biosynthesis protein DUF4604 PF15377.6 KFQ96495.1 - 4.6e-17 63.0 16.4 5.6e-17 62.7 16.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Asp-B-Hydro_N PF05279.11 KFQ96495.1 - 0.084 12.9 7.5 0.087 12.9 7.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Kinesin PF00225.23 KFQ96496.1 - 8.4e-99 330.6 0.1 8.4e-99 330.6 0.1 3.9 4 1 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 KFQ96496.1 - 4.5e-28 98.1 0.5 8.8e-26 90.6 0.0 3.8 2 0 0 2 2 2 1 Microtubule binding HMMR_C PF15908.5 KFQ96496.1 - 2e-08 34.7 13.8 2e-08 34.7 13.8 9.3 5 2 0 9 9 9 1 Hyaluronan mediated motility receptor C-terminal ADIP PF11559.8 KFQ96496.1 - 0.0093 16.1 12.5 0.0093 16.1 12.5 12.1 3 3 5 11 11 11 1 Afadin- and alpha -actinin-Binding Transglut_N PF00868.20 KFQ96497.1 - 8.1e-33 113.3 0.0 2.4e-32 111.7 0.0 1.9 2 0 0 2 2 2 1 Transglutaminase family Transglut_C PF00927.22 KFQ96497.1 - 1.6e-20 73.2 0.9 2.6e-12 46.8 0.1 2.7 3 0 0 3 3 3 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 KFQ96497.1 - 1.4e-15 57.7 0.1 3.2e-15 56.6 0.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily DHHC PF01529.20 KFQ96498.1 - 3.7e-37 127.4 14.2 3.7e-37 127.4 14.2 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF3615 PF12274.8 KFQ96498.1 - 0.0036 17.8 0.9 0.0068 16.9 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3615) IGFBP PF00219.18 KFQ96498.1 - 2.7 8.7 13.6 34 5.2 10.5 2.4 2 0 0 2 2 2 0 Insulin-like growth factor binding protein RNase_PH PF01138.21 KFQ96499.1 - 2.2e-23 83.2 0.0 3.4e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFQ96499.1 - 2.3e-11 43.5 0.1 6.5e-11 42.1 0.1 1.8 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Lectin_C PF00059.21 KFQ96500.1 - 3e-19 69.7 0.1 3.9e-19 69.4 0.1 1.1 1 0 0 1 1 1 1 Lectin C-type domain Chordopox_A33R PF05966.12 KFQ96500.1 - 0.00033 20.0 0.1 0.00042 19.6 0.1 1.1 1 0 0 1 1 1 1 Chordopoxvirus A33R protein DUF333 PF03891.15 KFQ96500.1 - 0.00061 20.0 0.3 0.29 11.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF333) CUB PF00431.20 KFQ96501.1 - 4.2e-05 23.8 0.0 3.8 7.9 0.0 4.3 4 0 0 4 4 4 3 CUB domain tRNA-synt_1 PF00133.22 KFQ96502.1 - 1.9e-47 161.9 4.9 6.4e-23 80.8 7.7 6.0 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KFQ96502.1 - 5.2e-32 111.1 0.0 2.1e-20 72.9 0.0 3.6 4 0 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KFQ96502.1 - 1.5e-11 44.4 0.4 3.1e-11 43.5 0.4 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 KFQ96502.1 - 3.6e-08 33.1 0.0 0.00016 21.3 0.0 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KFQ96502.1 - 0.00013 21.5 0.0 0.22 10.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 KFQ96502.1 - 0.011 14.7 0.0 0.63 8.9 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (K) LIM PF00412.22 KFQ96503.1 - 1.4e-32 111.6 34.2 2.6e-12 46.8 5.5 3.2 3 0 0 3 3 3 3 LIM domain Syja_N PF02383.18 KFQ96504.1 - 1.2e-94 317.3 0.6 1.5e-94 316.9 0.6 1.1 1 0 0 1 1 1 1 SacI homology domain LSM PF01423.22 KFQ96505.1 - 4e-19 68.1 0.7 6.1e-19 67.5 0.7 1.3 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KFQ96505.1 - 0.0093 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Hfq protein Gemin7 PF11095.8 KFQ96505.1 - 0.041 13.8 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) SM-ATX PF14438.6 KFQ96505.1 - 0.048 13.8 0.1 0.068 13.3 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain API5 PF05918.11 KFQ96505.1 - 1.7 7.4 3.3 2.2 7.0 3.3 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) SNF PF00209.18 KFQ96506.1 - 1.2e-174 581.9 31.0 1.5e-174 581.5 31.0 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family TraL PF07178.11 KFQ96506.1 - 0.95 10.0 0.1 0.95 10.0 0.1 4.4 5 0 0 5 5 5 0 TraL protein Leu_zip PF15294.6 KFQ96507.1 - 7.1e-126 419.4 32.0 8e-126 419.2 32.0 1.0 1 0 0 1 1 1 1 Leucine zipper HisKA_3 PF07730.13 KFQ96507.1 - 0.64 10.6 3.9 23 5.6 0.4 2.8 2 0 0 2 2 2 0 Histidine kinase DUF4407 PF14362.6 KFQ96507.1 - 2.9 7.1 17.7 3.2 7.0 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) FYVE PF01363.21 KFQ96508.1 - 2.9e-16 59.4 18.5 1e-15 57.6 18.5 2.0 1 0 0 1 1 1 1 FYVE zinc finger RUN PF02759.19 KFQ96508.1 - 2.9e-08 33.7 0.0 2.9e-08 33.7 0.0 5.8 4 1 0 4 4 4 1 RUN domain GOLD_2 PF13897.6 KFQ96508.1 - 6.4e-05 23.5 0.0 6.4e-05 23.5 0.0 6.5 5 3 3 8 8 8 1 Golgi-dynamics membrane-trafficking 7tm_1 PF00001.21 KFQ96509.1 - 3e-50 171.0 23.5 4.1e-50 170.5 23.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ96509.1 - 0.00077 18.9 24.7 0.0011 18.5 24.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 KFQ96510.1 - 5.1e-55 186.6 19.7 6.4e-55 186.3 19.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ96510.1 - 3.7e-10 39.6 22.8 4.8e-10 39.3 22.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Sprouty PF05210.13 KFQ96510.1 - 0.015 15.7 2.1 0.88 10.0 0.1 2.6 2 0 0 2 2 2 0 Sprouty protein (Spry) ARL6IP6 PF15062.6 KFQ96510.1 - 0.017 15.2 1.0 3.8 7.7 0.1 2.8 1 1 1 2 2 2 0 Haemopoietic lineage transmembrane helix 7tm_4 PF13853.6 KFQ96510.1 - 0.048 13.4 18.4 0.44 10.2 18.4 2.6 1 1 0 1 1 1 0 Olfactory receptor PspC PF04024.12 KFQ96510.1 - 0.22 11.4 2.6 0.24 11.3 0.2 2.3 2 0 0 2 2 2 0 PspC domain 7tm_1 PF00001.21 KFQ96511.1 - 2.8e-53 180.9 18.9 3.6e-53 180.6 18.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ96511.1 - 5.2e-10 39.1 20.8 7.1e-10 38.7 20.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Sprouty PF05210.13 KFQ96511.1 - 0.14 12.5 1.7 0.94 9.9 0.1 2.4 2 0 0 2 2 2 0 Sprouty protein (Spry) DUF1614 PF07758.11 KFQ96511.1 - 0.58 10.2 5.1 0.21 11.6 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1614) BRCT PF00533.26 KFQ96512.1 - 1.5e-44 150.2 0.9 6.9e-18 64.8 0.1 4.2 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KFQ96512.1 - 2.7e-42 142.6 4.7 6e-24 83.8 0.8 3.9 4 0 0 4 4 4 3 twin BRCT domain BRCT_2 PF16589.5 KFQ96512.1 - 6.2e-19 68.2 1.7 1.2e-08 35.2 0.0 4.0 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KFQ96512.1 - 4.4e-15 55.7 0.0 3.3e-07 30.5 0.0 3.4 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 KFQ96512.1 - 2.8e-08 33.6 0.0 0.0031 17.3 0.0 3.6 3 0 0 3 3 3 3 Regulator of Ty1 transposition protein 107 BRCT domain CDV3 PF15359.6 KFQ96513.1 - 2.7e-43 147.6 8.3 3.8e-43 147.1 8.3 1.2 1 0 0 1 1 1 1 Carnitine deficiency-associated protein 3 MecA_N PF05223.11 KFQ96513.1 - 0.22 11.8 2.2 4 7.7 0.6 2.1 2 0 0 2 2 2 0 NTF2-like N-terminal transpeptidase domain Filament PF00038.21 KFQ96514.1 - 1e-57 196.1 24.3 1.3e-57 195.8 24.3 1.0 1 0 0 1 1 1 1 Intermediate filament protein Lectin_N PF03954.14 KFQ96514.1 - 0.05 13.3 4.3 0.4 10.4 2.3 2.4 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Baculo_PEP_C PF04513.12 KFQ96514.1 - 0.1 12.7 1.3 2.4 8.2 0.1 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FTA4 PF13093.6 KFQ96514.1 - 1.5 8.7 12.6 7.2 6.4 12.6 2.0 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Prominin PF05478.11 KFQ96514.1 - 1.7 6.5 6.5 0.75 7.7 2.3 2.0 2 0 0 2 2 2 0 Prominin DUF1759 PF03564.15 KFQ96514.1 - 4.5 7.2 7.5 2.2 8.2 0.8 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1759) TMEM108 PF15759.5 KFQ96515.1 - 2.1e-134 449.4 8.4 2.4e-134 449.2 8.4 1.0 1 0 0 1 1 1 1 TMEM108 family TPR_12 PF13424.6 KFQ96517.1 - 9.6e-74 243.7 23.5 9.5e-19 67.5 0.0 7.3 3 2 3 7 7 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ96517.1 - 5e-66 217.0 23.5 7.1e-12 44.8 0.5 9.5 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ96517.1 - 3.9e-31 105.6 34.8 6.7e-06 25.7 2.7 9.1 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ96517.1 - 6.5e-31 104.1 19.5 0.00031 20.6 0.1 10.2 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ96517.1 - 4.8e-23 79.4 33.3 9.3e-05 22.4 1.6 9.6 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ96517.1 - 6.5e-20 69.6 33.7 0.0029 17.6 0.2 9.1 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_MalT PF17874.1 KFQ96517.1 - 3.7e-17 62.7 9.8 0.00012 21.6 2.5 4.6 1 1 3 4 4 4 4 MalT-like TPR region TPR_16 PF13432.6 KFQ96517.1 - 5.6e-12 46.1 15.3 0.00081 20.0 0.2 7.3 3 2 5 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ96517.1 - 1.5e-10 40.7 13.9 0.058 13.8 0.1 8.5 8 2 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ96517.1 - 5.7e-10 39.6 19.8 0.01 16.3 0.5 5.6 4 1 0 5 5 5 4 Tetratricopeptide repeat NACHT PF05729.12 KFQ96517.1 - 7.3e-07 29.3 0.5 1.7e-06 28.0 0.1 1.9 2 0 0 2 2 2 1 NACHT domain TPR_14 PF13428.6 KFQ96517.1 - 7.5e-07 29.5 16.9 4 8.5 0.2 8.5 5 2 3 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ96517.1 - 5.5e-06 26.0 24.1 0.28 10.9 0.2 8.1 8 0 0 8 8 8 2 TPR repeat TPR_6 PF13174.6 KFQ96517.1 - 0.00017 22.0 18.5 1.7 9.4 0.1 7.8 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_3 PF07720.12 KFQ96517.1 - 0.00075 19.4 21.4 1.8 8.6 0.4 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat DUF2225 PF09986.9 KFQ96517.1 - 0.0012 18.7 0.1 0.0012 18.7 0.1 4.7 2 1 1 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2225) KAP_NTPase PF07693.14 KFQ96517.1 - 0.0017 17.6 1.0 0.15 11.2 0.0 3.1 2 1 1 3 3 3 1 KAP family P-loop domain AAA_16 PF13191.6 KFQ96517.1 - 0.0019 18.6 0.1 0.0019 18.6 0.1 3.1 3 1 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 KFQ96517.1 - 0.0025 18.1 0.4 0.019 15.2 0.0 2.8 3 0 0 3 3 1 1 AAA domain AAA_19 PF13245.6 KFQ96517.1 - 0.0034 17.7 0.0 0.018 15.3 0.0 2.3 1 0 0 1 1 1 1 AAA domain MIT PF04212.18 KFQ96517.1 - 0.0094 16.0 21.7 2.9 8.0 2.4 6.3 4 1 1 5 5 5 1 MIT (microtubule interacting and transport) domain AAA_33 PF13671.6 KFQ96517.1 - 0.07 13.3 3.0 3.2 7.9 2.0 2.5 2 0 0 2 2 2 0 AAA domain 14-3-3 PF00244.20 KFQ96517.1 - 0.098 12.1 21.9 1.4 8.3 0.0 5.5 3 1 2 5 5 4 0 14-3-3 protein AAA PF00004.29 KFQ96517.1 - 0.13 12.7 0.0 0.48 10.9 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4404 PF14357.6 KFQ96517.1 - 0.17 12.5 14.5 15 6.3 0.0 6.6 4 4 3 7 7 7 0 Domain of unknown function (DUF4404) Tcf25 PF04910.14 KFQ96517.1 - 0.2 10.7 3.4 11 5.0 0.0 4.5 4 2 1 5 5 5 0 Transcriptional repressor TCF25 GIT_CC PF16559.5 KFQ96517.1 - 0.21 11.5 6.7 2.7 7.9 0.3 2.9 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor OmpH PF03938.14 KFQ96517.1 - 0.29 11.5 27.6 0.065 13.6 15.0 3.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Uso1_p115_C PF04871.13 KFQ96517.1 - 1.7 9.0 26.9 0.021 15.2 14.0 3.4 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region SHNi-TPR PF10516.9 KFQ96517.1 - 3.3 7.2 10.2 2.4 7.7 0.1 5.2 7 0 0 7 7 6 0 SHNi-TPR FliD_C PF07195.12 KFQ96517.1 - 3.5 7.0 10.7 13 5.1 0.2 3.2 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus ThiF PF00899.21 KFQ96518.1 - 3.2e-49 167.5 0.1 4.7e-49 167.0 0.1 1.2 1 0 0 1 1 1 1 ThiF family UDPG_MGDP_dh_N PF03721.14 KFQ96518.1 - 0.00081 19.0 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 KFQ96518.1 - 0.032 14.5 2.4 0.48 10.7 0.9 2.7 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KFQ96518.1 - 0.043 14.2 0.0 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KFQ96518.1 - 0.045 13.1 0.3 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KFQ96518.1 - 0.12 12.1 0.1 0.56 9.8 0.1 2.1 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 KFQ96518.1 - 0.15 11.3 0.3 0.24 10.6 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 KFQ96518.1 - 0.26 11.6 0.8 1.8 8.8 0.0 2.7 3 1 0 3 3 3 0 TrkA-N domain APH PF01636.23 KFQ96519.1 - 1.3e-45 156.2 0.0 2.1e-45 155.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.24 KFQ96519.1 - 9.6e-35 120.0 0.9 1.6e-34 119.3 0.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFQ96519.1 - 2.3e-18 66.2 0.0 4e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KFQ96519.1 - 8.1e-13 49.0 0.1 2.8e-12 47.3 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KFQ96519.1 - 1.8e-12 47.7 1.1 5.9e-12 46.0 1.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain EcKinase PF02958.20 KFQ96519.1 - 4.6e-05 22.9 0.0 8.5e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 KFQ96519.1 - 0.052 13.1 0.0 1.6 8.3 0.0 2.8 3 0 0 3 3 3 0 RIO1 family HpaB_N PF11794.8 KFQ96519.1 - 0.053 13.2 0.0 0.099 12.3 0.0 1.5 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF1679 PF07914.11 KFQ96519.1 - 0.07 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 KFQ96519.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase 7tm_1 PF00001.21 KFQ96520.1 - 1.3e-49 169.0 17.3 1.6e-49 168.6 17.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ96520.1 - 4e-07 29.7 15.9 5.2e-07 29.3 15.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx GYF_2 PF14237.6 KFQ96521.1 - 1.8e-18 66.1 1.0 4.5e-18 64.8 1.0 1.8 1 0 0 1 1 1 1 GYF domain 2 DnaJ PF00226.31 KFQ96521.1 - 2.6e-15 56.3 2.0 8.6e-15 54.6 0.1 2.5 2 0 0 2 2 2 1 DnaJ domain TetR_C_15 PF17918.1 KFQ96521.1 - 0.098 13.4 0.0 29 5.5 0.0 3.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain GYF PF02213.16 KFQ96521.1 - 0.11 12.2 4.1 0.068 12.8 1.8 1.9 2 0 0 2 2 2 0 GYF domain DUF3361 PF11841.8 KFQ96521.1 - 2.2 8.2 4.7 2.2 8.2 0.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) His_Phos_2 PF00328.22 KFQ96522.1 - 2.9e-34 119.1 3.7 5.7e-33 114.8 3.7 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Toxin_TOLIP PF00087.21 KFQ96522.1 - 0.23 11.7 1.7 0.35 11.1 0.3 2.0 2 0 0 2 2 2 0 Snake toxin and toxin-like protein DUF3640 PF12342.8 KFQ96524.1 - 0.042 13.6 0.2 0.1 12.3 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3640) Aldedh PF00171.22 KFQ96526.1 - 1.4e-55 188.7 0.1 4e-54 183.9 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Pkinase PF00069.25 KFQ96527.1 - 1.2e-70 237.9 0.1 3.5e-70 236.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ96527.1 - 3e-49 167.6 0.0 5.5e-49 166.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 KFQ96527.1 - 2e-25 89.6 3.1 3.8e-25 88.7 3.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Kdo PF06293.14 KFQ96527.1 - 1.8e-07 30.8 0.0 4.6e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFQ96527.1 - 7.6e-06 25.7 0.1 1.4e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KFQ96527.1 - 0.00024 20.0 0.2 0.00053 18.9 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KFQ96527.1 - 0.0043 16.4 0.0 0.02 14.2 0.0 2.0 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KFQ96527.1 - 0.0074 16.2 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family WD40 PF00400.32 KFQ96528.1 - 7.5e-66 216.5 27.0 2.9e-09 37.4 0.1 9.0 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ96528.1 - 2.8e-25 88.4 4.0 3.2e-06 27.4 0.1 6.4 2 2 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFQ96528.1 - 1.1e-07 31.2 0.0 0.051 12.5 0.0 4.9 2 2 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFQ96528.1 - 2e-07 31.1 0.0 0.43 10.4 0.0 4.0 2 2 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KFQ96528.1 - 6.9e-07 29.1 1.2 0.22 11.5 0.1 5.7 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat NLE PF08154.12 KFQ96528.1 - 1.9e-05 25.1 0.0 4e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain Frtz PF11768.8 KFQ96528.1 - 6.5e-05 21.4 0.0 0.18 10.1 0.0 3.0 2 1 1 3 3 3 3 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 KFQ96528.1 - 0.00092 18.0 2.7 19 3.7 0.0 4.7 3 2 2 5 5 5 0 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KFQ96528.1 - 0.00097 18.2 4.2 0.12 11.3 0.2 3.3 3 0 0 3 3 3 2 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 KFQ96528.1 - 0.0031 16.9 0.0 5.8 6.1 0.0 4.0 4 0 0 4 4 4 1 WD40-like domain Nucleoporin_N PF08801.11 KFQ96528.1 - 0.0057 15.5 1.1 9.3 4.9 0.1 3.9 2 1 1 4 4 4 1 Nup133 N terminal like FAD_binding_9 PF08021.11 KFQ96528.1 - 0.02 15.1 0.0 0.057 13.6 0.0 1.7 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain nos_propeller PF18764.1 KFQ96528.1 - 0.16 11.9 0.2 15 5.6 0.0 3.7 3 1 1 4 4 4 0 Nitrous oxide reductase propeller repeat RGS PF00615.19 KFQ96529.1 - 3.7e-31 107.8 1.7 2.9e-12 46.9 0.1 3.5 3 0 0 3 3 3 3 Regulator of G protein signaling domain L_HMGIC_fpl PF10242.9 KFQ96530.1 - 4.6e-14 53.0 0.5 5.7e-14 52.7 0.5 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein DUF1240 PF06836.12 KFQ96530.1 - 0.069 13.7 0.2 0.086 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) Claudin_2 PF13903.6 KFQ96530.1 - 0.088 12.6 0.4 0.097 12.4 0.4 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction AstE_AspA PF04952.14 KFQ96532.1 - 7.5e-62 209.0 0.0 8.5e-62 208.9 0.0 1.0 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Ank_2 PF12796.7 KFQ96533.1 - 2.2e-18 66.6 8.2 2.6e-08 34.3 1.7 3.8 2 2 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFQ96533.1 - 3.8e-12 46.1 0.0 0.018 15.5 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KFQ96533.1 - 5e-12 44.9 0.3 0.0044 17.4 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KFQ96533.1 - 1e-10 41.6 0.2 0.013 15.8 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFQ96533.1 - 2.2e-09 37.7 0.2 0.0072 16.9 0.0 5.3 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ion_trans PF00520.31 KFQ96533.1 - 1.1e-08 34.6 19.3 1.7e-08 34.0 19.3 1.3 1 0 0 1 1 1 1 Ion transport protein DUF2070 PF09843.9 KFQ96533.1 - 9.3 4.4 17.8 13 3.9 17.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ion_trans PF00520.31 KFQ96534.1 - 2.1e-14 53.3 18.4 3.2e-14 52.7 18.4 1.2 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 KFQ96534.1 - 3.9e-14 53.0 1.4 2.1e-07 31.4 0.2 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFQ96534.1 - 1.2e-09 37.5 0.2 0.0069 16.8 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KFQ96534.1 - 6.7e-09 35.8 0.3 0.00022 21.5 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KFQ96534.1 - 5.8e-07 29.7 0.2 0.1 13.0 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFQ96534.1 - 2.3e-06 28.0 0.0 0.0045 17.5 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PKD_channel PF08016.12 KFQ96534.1 - 0.0035 16.1 9.0 0.0082 14.9 9.0 1.6 1 0 0 1 1 1 1 Polycystin cation channel DUF3562 PF12085.8 KFQ96534.1 - 0.057 13.0 0.0 5.3 6.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3562) CNOT1_HEAT PF16418.5 KFQ96534.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 HEAT repeat FGGY_N PF00370.21 KFQ96535.1 - 1.6e-24 86.9 0.1 2.6e-23 82.8 0.1 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KFQ96535.1 - 0.005 16.4 0.0 0.009 15.5 0.0 1.6 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family PQ-loop PF04193.14 KFQ96536.1 - 5.7e-41 138.1 12.6 1.1e-20 73.1 1.7 2.7 2 0 0 2 2 2 2 PQ loop repeat DUF4929 PF16283.5 KFQ96536.1 - 0.022 13.8 0.1 0.032 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4929) PDZ PF00595.24 KFQ96537.1 - 3.5e-20 72.1 0.2 4.4e-20 71.8 0.2 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFQ96537.1 - 1.8e-11 44.2 0.3 2.5e-11 43.7 0.3 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFQ96537.1 - 3.9e-11 42.6 0.1 7.2e-11 41.8 0.1 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KFQ96537.1 - 0.13 12.6 0.1 0.23 11.8 0.0 1.4 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain Rab5ip PF07019.12 KFQ96538.1 - 3.8e-23 81.9 8.1 4.6e-23 81.6 8.1 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF5084 PF16894.5 KFQ96538.1 - 0.046 14.1 1.4 0.064 13.7 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5084) P2X_receptor PF00864.19 KFQ96539.1 - 6.6e-166 551.9 0.7 7.5e-166 551.7 0.7 1.0 1 0 0 1 1 1 1 ATP P2X receptor VWA PF00092.28 KFQ96540.1 - 8.6e-34 117.3 0.0 1.9e-33 116.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Integrin_alpha2 PF08441.12 KFQ96540.1 - 8.7e-26 90.8 6.3 1.6e-25 89.9 6.3 1.4 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 KFQ96540.1 - 4.3e-20 71.5 7.7 2.1e-08 34.1 0.4 3.7 3 0 0 3 3 3 3 FG-GAP repeat VWA_2 PF13519.6 KFQ96540.1 - 2.4e-12 47.4 0.0 5.6e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VCBS PF13517.6 KFQ96540.1 - 6.5e-11 42.7 0.2 9.8e-08 32.5 0.1 3.0 2 0 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella HisK_sensor PF18698.1 KFQ96540.1 - 0.0038 17.6 0.4 0.24 11.8 0.0 3.4 3 1 0 3 3 3 1 Histidine kinase sensor domain SSV1_ORF_D-335 PF07935.11 KFQ96540.1 - 0.16 12.3 0.1 0.42 10.9 0.1 1.6 1 0 0 1 1 1 0 ORF D-335-like protein Ank_2 PF12796.7 KFQ96541.1 - 1.4e-21 76.9 0.2 1.7e-10 41.3 0.1 4.1 2 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFQ96541.1 - 7.9e-13 47.3 0.0 0.00018 21.7 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KFQ96541.1 - 2.1e-12 47.0 0.1 4.6e-05 23.6 0.0 4.6 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFQ96541.1 - 3.7e-11 43.3 0.0 0.0047 17.5 0.0 4.9 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ion_trans PF00520.31 KFQ96541.1 - 1e-10 41.3 21.3 1.5e-10 40.7 21.3 1.3 1 0 0 1 1 1 1 Ion transport protein Ank PF00023.30 KFQ96541.1 - 2.3e-10 40.4 0.1 0.00047 20.5 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat PKD_channel PF08016.12 KFQ96541.1 - 0.026 13.2 15.4 0.043 12.5 15.0 1.5 1 1 0 1 1 1 0 Polycystin cation channel ubiquitin PF00240.23 KFQ96542.1 - 1.6e-35 120.7 0.3 2e-35 120.4 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KFQ96542.1 - 1.9e-17 62.8 0.4 2.2e-17 62.6 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFQ96542.1 - 1e-06 29.1 0.1 4.3e-06 27.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KFQ96542.1 - 0.0012 18.7 0.1 0.0015 18.4 0.1 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KFQ96542.1 - 0.0014 18.7 0.1 0.0033 17.5 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KFQ96542.1 - 0.0021 18.4 0.1 0.0027 18.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 KFQ96542.1 - 0.0037 17.3 0.2 3 8.0 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-like domain DUF2407 PF10302.9 KFQ96542.1 - 0.036 14.6 0.0 0.044 14.4 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 KFQ96542.1 - 0.13 12.1 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain GFA PF04828.14 KFQ96543.1 - 5e-09 36.4 2.7 5e-09 36.4 2.7 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme PIG-L PF02585.17 KFQ96544.1 - 6.6e-11 43.0 0.0 2e-10 41.4 0.0 1.7 2 0 0 2 2 2 1 GlcNAc-PI de-N-acetylase GPS2_interact PF15784.5 KFQ96545.1 - 9.7e-36 122.1 5.0 9.7e-36 122.1 5.0 7.0 10 0 0 10 10 10 1 G-protein pathway suppressor 2-interacting domain Myb_DNA-binding PF00249.31 KFQ96545.1 - 6.7e-17 61.4 0.3 2.2e-12 47.0 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFQ96545.1 - 0.0026 18.0 2.3 0.066 13.5 0.3 3.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain TPR_12 PF13424.6 KFQ96546.1 - 5e-24 84.4 16.8 2e-12 47.2 0.4 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KFQ96546.1 - 5.9e-14 52.2 15.6 1.2e-07 31.5 2.0 2.4 1 1 1 2 2 2 2 MalT-like TPR region TPR_2 PF07719.17 KFQ96546.1 - 1.1e-13 50.1 16.4 0.0046 17.0 0.4 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ96546.1 - 1.4e-13 50.2 11.5 0.043 13.7 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ96546.1 - 7.7e-11 41.3 17.5 0.0072 16.1 0.5 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ96546.1 - 4e-08 32.8 17.6 0.054 13.7 0.5 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ96546.1 - 4.6e-08 33.2 15.2 0.27 12.2 0.4 6.3 3 2 3 6 6 6 2 Tetratricopeptide repeat ComR_TPR PF18710.1 KFQ96546.1 - 2.2e-06 27.4 9.1 1.3e-05 24.8 5.0 2.6 2 1 0 2 2 2 1 ComR tetratricopeptide TPR_7 PF13176.6 KFQ96546.1 - 3e-06 26.9 11.9 0.038 14.0 0.2 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ96546.1 - 4.4e-06 27.1 19.7 0.0082 16.6 4.0 4.3 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ96546.1 - 6.3e-05 23.5 9.6 0.017 15.7 1.2 5.1 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ96546.1 - 0.00081 19.6 12.1 1.8 9.1 0.0 6.2 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 KFQ96546.1 - 0.00085 19.7 0.0 3 8.8 0.0 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat ANAPC5 PF12862.7 KFQ96546.1 - 0.011 15.8 10.4 0.081 13.0 0.8 3.5 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_21 PF09976.9 KFQ96546.1 - 0.035 13.8 19.5 0.29 10.8 7.1 3.0 2 2 0 2 2 2 0 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 KFQ96546.1 - 0.039 14.2 12.9 0.16 12.2 0.1 4.1 2 2 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 KFQ96546.1 - 0.18 12.1 2.0 5 7.6 0.1 3.8 5 0 0 5 5 4 0 PPR repeat T3SS_basalb_I PF17001.5 KFQ96546.1 - 2.2 9.0 9.4 2.3 8.8 2.4 3.2 2 2 1 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI Complex1_LYR_2 PF13233.6 KFQ96546.1 - 3.4 8.5 5.9 11 6.9 5.9 2.0 1 1 0 1 1 1 0 Complex1_LYR-like MIT PF04212.18 KFQ96546.1 - 4.5 7.4 14.4 2.8 8.1 0.4 4.7 5 1 1 6 6 6 0 MIT (microtubule interacting and transport) domain SWIM PF04434.17 KFQ96547.1 - 5.4e-07 29.1 3.2 8.6e-07 28.5 3.2 1.4 1 0 0 1 1 1 1 SWIM zinc finger 7tm_1 PF00001.21 KFQ96548.1 - 9.5e-54 182.5 16.0 1.2e-53 182.1 16.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ96548.1 - 3.3e-13 49.6 19.0 2.2e-08 33.8 5.1 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFQ96548.1 - 6.5e-13 49.0 17.2 8.9e-13 48.6 17.2 1.1 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFQ96548.1 - 3.6e-06 26.8 18.1 3.6e-06 26.8 18.1 2.7 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx GPR_Gpa2_C PF11970.8 KFQ96548.1 - 0.0039 17.2 0.3 0.015 15.4 0.3 2.0 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term CH PF00307.31 KFQ96549.1 - 9.7e-22 77.2 0.4 3.8e-21 75.3 0.0 2.3 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFQ96549.1 - 6.9e-06 25.8 0.1 2.3e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 CAMSAP CH domain Tim17 PF02466.19 KFQ96550.1 - 3e-27 95.2 3.5 3.5e-27 95.0 3.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family RhoGAP PF00620.27 KFQ96551.1 - 2.9e-33 114.8 0.0 5.6e-33 113.9 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KFQ96551.1 - 1.7e-10 41.3 3.1 1.1e-09 38.7 1.9 2.7 2 1 0 2 2 2 1 PH domain RhoGEF PF00621.20 KFQ96551.1 - 1.3e-09 38.6 1.0 1.8e-09 38.1 0.1 1.7 2 0 0 2 2 2 1 RhoGEF domain C2 PF00168.30 KFQ96551.1 - 0.0029 17.9 0.0 0.0081 16.4 0.0 1.8 1 0 0 1 1 1 1 C2 domain Phage_antiter_Q PF06323.11 KFQ96551.1 - 0.009 15.6 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 Phage antitermination protein Q IQ_SEC7_PH PF16453.5 KFQ96551.1 - 0.068 13.1 0.1 0.38 10.7 0.0 2.1 2 0 0 2 2 2 0 PH domain Tox-PL-2 PF15643.6 KFQ96551.1 - 0.11 12.6 0.1 0.34 11.0 0.1 1.8 1 0 0 1 1 1 0 Papain fold toxin 2 V-SNARE_C PF12352.8 KFQ96552.1 - 6.6e-22 77.6 3.6 6.6e-22 77.6 3.6 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KFQ96552.1 - 0.0046 16.8 0.9 0.031 14.2 0.2 2.2 2 0 0 2 2 2 1 Sec20 DUF1664 PF07889.12 KFQ96552.1 - 0.12 12.4 1.7 0.21 11.6 0.5 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Muted PF14942.6 KFQ96552.1 - 0.21 11.9 4.8 1.6 9.1 2.0 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Peptidase_M14 PF00246.24 KFQ96553.1 - 1.1e-172 573.5 0.0 1.2e-84 284.5 0.1 3.2 3 0 0 3 3 3 3 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 KFQ96553.1 - 3.1e-35 120.3 8.4 1e-13 51.3 0.4 3.4 3 0 0 3 3 3 3 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KFQ96553.1 - 4.2e-20 71.5 2.4 2.1e-08 34.0 0.1 3.4 3 0 0 3 3 3 3 CarboxypepD_reg-like domain AstE_AspA PF04952.14 KFQ96553.1 - 0.00061 19.0 0.2 0.014 14.5 0.1 2.4 2 0 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family PEGA PF08308.11 KFQ96553.1 - 0.00079 19.3 0.1 0.52 10.2 0.0 3.3 3 0 0 3 3 3 2 PEGA domain DUF3823 PF12866.7 KFQ96553.1 - 0.053 13.8 0.1 0.86 9.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3823) N-terminal domain Ig_3 PF13927.6 KFQ96554.1 - 3.8e-20 72.3 4.0 1.1e-15 58.0 1.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFQ96554.1 - 1.4e-19 70.2 1.5 2.5e-14 53.3 0.3 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFQ96554.1 - 2.8e-18 65.9 1.8 1.3e-11 44.5 0.3 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFQ96554.1 - 1.4e-17 63.5 0.8 1.6e-16 60.1 0.1 2.3 2 1 0 2 2 2 1 Immunoglobulin I-set domain V-set PF07686.17 KFQ96554.1 - 1.2e-11 44.7 4.8 3e-09 37.0 1.0 3.8 2 2 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFQ96554.1 - 5.8e-07 29.5 3.2 7.4e-05 22.7 0.5 2.9 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFQ96554.1 - 2e-05 24.7 2.8 0.0096 16.2 0.8 2.7 2 1 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFQ96554.1 - 0.00016 21.2 0.0 0.87 9.2 0.1 2.8 3 0 0 3 3 3 2 Immunoglobulin domain Ig_5 PF16681.5 KFQ96554.1 - 0.0011 19.3 2.2 0.013 15.9 0.3 2.8 2 2 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFQ96554.1 - 0.0046 17.0 0.1 0.069 13.2 0.0 2.4 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain C1-set PF07654.15 KFQ96554.1 - 0.0057 17.0 2.7 0.0095 16.3 1.2 2.0 2 0 0 2 2 2 1 Immunoglobulin C1-set domain IgGFc_binding PF17517.2 KFQ96554.1 - 0.0088 15.4 0.6 1.1 8.5 0.1 2.1 1 1 1 2 2 2 2 IgGFc binding protein Adeno_E3_CR1 PF02440.15 KFQ96554.1 - 0.021 14.6 1.3 0.055 13.3 0.5 2.0 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 Ig_C17orf99 PF17736.1 KFQ96554.1 - 0.043 13.8 0.3 0.25 11.4 0.0 2.3 3 0 0 3 3 3 0 C17orf99 Ig domain C2-set PF05790.15 KFQ96554.1 - 0.047 13.9 6.0 3 8.1 0.1 3.6 3 1 1 4 4 4 0 Immunoglobulin C2-set domain Invasin_D3 PF09134.10 KFQ96554.1 - 0.067 13.5 0.3 0.58 10.5 0.1 2.3 1 1 1 2 2 2 0 Invasin, domain 3 Peptidase_C1_2 PF03051.15 KFQ96555.1 - 1.1e-198 660.4 1.8 1.3e-198 660.2 1.8 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KFQ96555.1 - 1.5e-06 28.5 1.7 0.011 15.9 0.9 2.6 2 1 0 2 2 2 2 Papain family cysteine protease SNF PF00209.18 KFQ96556.1 - 1.4e-227 756.6 37.1 1.6e-227 756.4 37.1 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family 5HT_transport_N PF03491.13 KFQ96556.1 - 2.6e-07 30.7 1.3 5.6e-07 29.6 1.3 1.5 1 0 0 1 1 1 1 Serotonin (5-HT) neurotransmitter transporter, N-terminus DUF2040 PF09745.9 KFQ96557.1 - 3.8e-37 127.0 23.2 3.8e-37 127.0 23.2 5.8 2 1 4 6 6 6 1 Coiled-coil domain-containing protein 55 (DUF2040) DSPc PF00782.20 KFQ96558.1 - 2.5e-34 118.0 0.0 9.4e-34 116.1 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DEK_C PF08766.11 KFQ96558.1 - 4.7e-11 42.4 5.1 1.1e-10 41.3 5.1 1.7 1 0 0 1 1 1 1 DEK C terminal domain Y_phosphatase PF00102.27 KFQ96558.1 - 0.028 14.0 0.0 0.087 12.4 0.0 1.8 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF1899 PF08953.11 KFQ96559.1 - 1.4e-31 108.1 0.1 4.2e-31 106.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KFQ96559.1 - 3e-22 78.2 0.1 6e-22 77.3 0.1 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KFQ96559.1 - 1.4e-13 51.0 2.7 0.00017 22.3 0.3 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ96559.1 - 3.7e-07 30.4 0.6 0.019 15.2 0.0 2.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Trimer_CC PF08954.11 KFQ96559.1 - 5e-05 22.8 0.1 0.0053 16.3 0.1 2.3 2 0 0 2 2 2 1 Trimerisation motif CEP209_CC5 PF16574.5 KFQ96559.1 - 0.063 13.4 0.3 0.13 12.4 0.3 1.5 1 0 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 MetOD2 PF18548.1 KFQ96559.1 - 0.18 11.9 0.1 0.37 10.9 0.1 1.4 1 0 0 1 1 1 0 Metanogen output domain 2 GPCR_chapero_1 PF11904.8 KFQ96560.1 - 1.9e-98 329.7 0.0 2.2e-98 329.5 0.0 1.1 1 0 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.7 KFQ96560.1 - 2.6e-10 40.7 0.0 5.2e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ96560.1 - 1.3e-08 35.2 0.0 2.8e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFQ96560.1 - 1.9e-08 34.4 0.0 5.1e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KFQ96560.1 - 7.3e-07 29.4 0.0 3.4e-06 27.2 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KFQ96560.1 - 2e-06 27.7 0.0 0.00052 20.2 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat UIM PF02809.20 KFQ96560.1 - 0.49 10.4 4.0 0.58 10.2 2.1 2.2 2 0 0 2 2 2 0 Ubiquitin interaction motif AIP3 PF03915.13 KFQ96561.1 - 3.7e-14 52.7 14.8 3.3e-09 36.4 0.0 2.5 2 1 0 2 2 2 2 Actin interacting protein 3 LMBR1 PF04791.16 KFQ96561.1 - 0.87 8.4 1.8 1.2 7.9 1.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein RhoGAP PF00620.27 KFQ96562.1 - 3.7e-24 85.3 0.0 3.9e-24 85.2 0.0 1.0 1 0 0 1 1 1 1 RhoGAP domain SOCS_box PF07525.16 KFQ96563.1 - 6.1e-10 39.3 3.8 6.1e-10 39.3 3.8 2.3 2 0 0 2 2 2 1 SOCS box SH2 PF00017.24 KFQ96563.1 - 4.2e-09 36.4 0.0 1e-08 35.1 0.0 1.7 1 1 0 1 1 1 1 SH2 domain Tim44 PF04280.15 KFQ96564.1 - 1.2e-32 113.0 0.0 1.7e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.11 KFQ96564.1 - 0.0029 16.7 0.0 0.0039 16.3 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein ChaB PF06150.12 KFQ96564.1 - 0.054 14.1 0.4 0.11 13.1 0.1 1.7 2 0 0 2 2 2 0 ChaB Kri1 PF05178.12 KFQ96564.1 - 0.16 12.6 0.3 0.16 12.6 0.3 1.5 2 0 0 2 2 2 0 KRI1-like family Peptidase_M1 PF01433.20 KFQ96565.1 - 2e-92 308.7 0.5 3.1e-92 308.1 0.5 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KFQ96565.1 - 2e-87 293.7 0.0 1.2e-86 291.1 0.0 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KFQ96565.1 - 1.7e-51 175.1 0.1 3.1e-51 174.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain HEAT PF02985.22 KFQ96566.1 - 3.4e-18 64.2 6.5 4.1e-05 23.5 0.0 9.3 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.6 KFQ96566.1 - 1.1e-15 57.8 4.1 2.5e-11 43.8 0.0 6.4 7 1 1 8 8 8 1 HEAT-like repeat IBN_N PF03810.19 KFQ96566.1 - 1.5e-10 40.8 0.6 1.8e-09 37.4 0.0 3.0 2 1 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KFQ96566.1 - 1.7e-08 34.7 0.2 0.00079 19.8 0.0 5.3 2 2 3 5 5 5 3 HEAT repeats Arm PF00514.23 KFQ96566.1 - 1.3e-07 31.4 6.4 0.0031 17.5 0.0 5.1 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KFQ96566.1 - 2.2e-05 24.5 3.8 0.014 15.5 0.0 3.6 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KFQ96566.1 - 5.6e-05 22.8 3.4 0.48 9.9 0.0 4.3 3 1 1 4 4 4 2 CLASP N terminal V-ATPase_H_C PF11698.8 KFQ96566.1 - 0.12 12.4 5.3 0.6 10.2 0.3 3.4 3 0 0 3 3 3 0 V-ATPase subunit H Ribosomal_L10 PF00466.20 KFQ96567.1 - 1e-06 28.8 0.2 1.6e-06 28.1 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 CCDC23 PF15674.5 KFQ96567.1 - 1.6 8.8 3.8 0.51 10.4 0.3 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 23 LRR_4 PF12799.7 KFQ96568.1 - 1.9e-15 56.7 5.8 2.3e-07 31.0 0.3 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFQ96568.1 - 1.5e-12 47.1 5.8 5.8e-07 29.2 1.0 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 KFQ96568.1 - 4.3e-07 29.5 2.5 0.0054 16.7 0.1 3.9 4 0 0 4 4 4 2 Leucine Rich repeat LRR_9 PF14580.6 KFQ96568.1 - 4.6e-06 26.2 0.8 1.1e-05 25.1 0.4 1.6 1 1 1 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 KFQ96568.1 - 0.0053 17.1 10.0 0.48 11.2 0.1 4.5 4 0 0 4 4 4 1 Leucine Rich Repeat Peptidase_C69 PF03577.15 KFQ96569.1 - 1.4e-09 37.4 0.0 1.8e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C69 AAT PF03417.16 KFQ96569.1 - 0.018 14.7 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase zf-C2H2 PF00096.26 KFQ96570.1 - 8.3e-08 32.3 8.8 1.7e-05 25.0 0.6 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ96570.1 - 3.4e-06 27.2 0.2 3.4e-06 27.2 0.2 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ96570.1 - 0.0079 17.0 17.0 0.01 16.6 0.6 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger AAA_7 PF12775.7 KFQ96570.1 - 0.087 12.3 0.1 0.37 10.3 0.1 1.9 1 1 1 2 2 2 0 P-loop containing dynein motor region Putative_PNPOx PF01243.20 KFQ96571.1 - 4.4e-19 68.5 0.0 7.4e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 KFQ96571.1 - 2.8e-18 65.7 1.1 5e-18 64.9 1.1 1.4 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 KFQ96571.1 - 0.00086 19.9 0.0 0.0025 18.4 0.0 1.8 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ATAD4 PF15321.6 KFQ96572.1 - 1e-21 78.1 1.2 2.4e-21 76.9 1.2 1.5 1 1 0 1 1 1 1 ATPase family AAA domain containing 4 DUF773 PF05600.12 KFQ96573.1 - 2e-39 135.8 0.1 2.2e-39 135.6 0.1 1.0 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 DUF3849 PF12960.7 KFQ96573.1 - 0.089 12.8 0.0 0.11 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) TPR_19 PF14559.6 KFQ96573.1 - 0.1 13.1 0.8 0.55 10.8 0.1 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF773 PF05600.12 KFQ96574.1 - 5e-52 177.3 0.0 3.7e-27 95.3 0.1 2.0 1 1 1 2 2 2 2 CDK5 regulatory subunit-associated protein 3 Clat_adaptor_s PF01217.20 KFQ96575.1 - 1.3e-30 106.2 0.0 1.4e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF5392 PF17370.2 KFQ96575.1 - 0.056 13.5 0.0 0.066 13.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5392) Chromo_shadow PF01393.19 KFQ96576.1 - 7.9e-34 115.5 0.1 6.8e-31 106.1 0.0 2.5 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 KFQ96576.1 - 7e-23 80.3 0.4 1.6e-18 66.3 0.4 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 KFQ96576.1 - 0.0013 18.9 0.2 0.0094 16.1 0.2 2.0 2 0 0 2 2 2 1 Polycomb-like MTF2 factor 2 CDC45 PF02724.14 KFQ96576.1 - 0.81 7.9 5.6 0.87 7.8 5.6 1.1 1 0 0 1 1 1 0 CDC45-like protein ELM2 PF01448.24 KFQ96576.1 - 9.3 7.1 7.3 1.6 9.6 0.8 2.4 2 1 0 2 2 2 0 ELM2 domain PX PF00787.24 KFQ96577.1 - 1.1e-26 93.1 0.4 1.3e-26 92.8 0.4 1.1 1 0 0 1 1 1 1 PX domain PaO PF08417.12 KFQ96577.1 - 0.14 12.3 0.0 0.21 11.7 0.0 1.4 1 1 0 1 1 1 0 Pheophorbide a oxygenase PH PF00169.29 KFQ96578.1 - 1.7e-12 47.7 0.9 2e-12 47.6 0.9 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFQ96578.1 - 8.2e-05 23.0 0.9 9.3e-05 22.8 0.9 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KFQ96578.1 - 0.0088 16.1 0.0 0.01 15.9 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFQ96578.1 - 0.089 13.1 0.5 0.11 12.8 0.5 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain DUF4813 PF16072.5 KFQ96579.1 - 1.9e-05 24.5 44.1 0.76 9.4 8.0 4.8 1 1 3 4 4 4 4 Domain of unknown function (DUF4813) Homeodomain PF00046.29 KFQ96581.1 - 2.7e-22 78.3 7.2 3.6e-22 78.0 7.2 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ96581.1 - 0.054 13.4 4.0 0.061 13.2 0.6 2.2 2 0 0 2 2 2 0 Homeobox KN domain Homeodomain PF00046.29 KFQ96583.1 - 5.6e-22 77.4 8.7 8.5e-22 76.8 8.7 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ96583.1 - 0.15 12.0 0.9 0.35 10.8 0.9 1.6 1 0 0 1 1 1 0 Homeobox KN domain DUF2209 PF09974.9 KFQ96583.1 - 0.18 12.1 0.1 0.26 11.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Homeodomain PF00046.29 KFQ96584.1 - 6.9e-22 77.1 8.1 1e-21 76.5 8.1 1.3 1 0 0 1 1 1 1 Homeodomain DUF2209 PF09974.9 KFQ96584.1 - 0.054 13.8 0.1 0.074 13.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Hox9_act PF04617.13 KFQ96585.1 - 4.9e-59 200.2 4.6 7.3e-59 199.6 4.6 1.3 1 0 0 1 1 1 1 Hox9 activation region Homeodomain PF00046.29 KFQ96585.1 - 6.6e-21 73.9 6.3 1.1e-20 73.2 6.3 1.4 1 0 0 1 1 1 1 Homeodomain HTH_23 PF13384.6 KFQ96585.1 - 0.0037 17.0 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain Homeobox_KN PF05920.11 KFQ96585.1 - 0.065 13.1 0.3 0.15 12.0 0.3 1.6 1 0 0 1 1 1 0 Homeobox KN domain SKICH PF17751.1 KFQ96586.1 - 1.2e-31 109.3 4.5 2.8e-31 108.1 2.4 2.4 2 0 0 2 2 2 1 SKICH domain Zn-C2H2_12 PF18112.1 KFQ96586.1 - 2.3e-10 40.7 11.4 1.7e-07 31.6 0.9 2.8 2 0 0 2 2 2 2 Autophagy receptor zinc finger-C2H2 domain DUF4201 PF13870.6 KFQ96586.1 - 0.0061 16.3 5.3 0.0061 16.3 5.3 3.5 2 1 1 3 3 3 1 Domain of unknown function (DUF4201) KASH_CCD PF14662.6 KFQ96586.1 - 0.013 15.3 62.9 0.032 14.0 43.3 3.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH zf-C2H2_4 PF13894.6 KFQ96586.1 - 0.014 16.1 4.0 2.7 9.0 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger UBZ_FAAP20 PF15750.5 KFQ96586.1 - 0.082 12.9 5.9 2.9 7.9 0.9 3.3 1 1 1 2 2 2 0 Ubiquitin-binding zinc-finger zf-Di19 PF05605.12 KFQ96586.1 - 0.45 10.8 5.1 3.4 8.1 5.1 2.5 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding WD40_alt PF14077.6 KFQ96586.1 - 1 9.3 8.9 2.2 8.2 1.7 3.7 2 2 1 3 3 3 0 Alternative WD40 repeat motif ZapB PF06005.12 KFQ96586.1 - 1.6 9.2 67.4 0.12 12.8 16.3 5.2 1 1 3 4 4 4 0 Cell division protein ZapB GAS PF13851.6 KFQ96586.1 - 2.4 7.5 62.7 0.1 11.9 22.3 3.8 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding ATP-synt_C PF00137.21 KFQ96587.1 - 5.2e-12 45.9 12.4 6.4e-12 45.6 12.4 1.1 1 0 0 1 1 1 1 ATP synthase subunit C EAP30 PF04157.16 KFQ96588.1 - 2.3e-76 256.2 0.1 2.7e-76 256.0 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family ZapD PF07072.11 KFQ96588.1 - 0.033 13.9 2.3 7.8 6.2 0.0 3.0 3 0 0 3 3 3 0 Cell division protein Plasmid_RAQPRD PF09686.10 KFQ96588.1 - 0.059 13.6 0.1 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) EutK_C PF16365.5 KFQ96588.1 - 0.17 12.0 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilization protein EutK C-terminus Phage_Mu_Gam PF07352.12 KFQ96588.1 - 4.1 7.3 7.3 0.51 10.2 2.1 2.0 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein Hormone_2 PF00123.20 KFQ96589.1 - 1.9e-10 40.4 6.0 8.8e-09 35.1 0.1 3.3 3 0 0 3 3 3 3 Peptide hormone KH_1 PF00013.29 KFQ96590.1 - 2.3e-58 193.9 12.1 2.3e-14 52.9 0.1 4.5 4 0 0 4 4 4 4 KH domain KH_2 PF07650.17 KFQ96590.1 - 4.3e-19 68.1 2.8 0.0012 18.7 0.1 4.6 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 KFQ96590.1 - 3.2e-16 58.9 1.0 0.0044 16.9 0.0 5.1 5 0 0 5 5 5 4 KH domain KH_5 PF13184.6 KFQ96590.1 - 1.2e-08 34.9 3.9 0.37 10.9 0.1 4.4 4 0 0 4 4 4 3 NusA-like KH domain RRM_1 PF00076.22 KFQ96590.1 - 2.7e-08 33.5 0.0 5.7e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MOEP19 PF16005.5 KFQ96590.1 - 9.8e-08 31.9 0.2 0.054 13.5 0.0 4.3 4 0 0 4 4 4 2 KH-like RNA-binding domain RRM_occluded PF16842.5 KFQ96590.1 - 0.01 15.7 0.0 0.049 13.5 0.0 2.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_5 PF13893.6 KFQ96590.1 - 0.025 14.2 0.2 0.087 12.4 0.1 1.9 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-gamma PF00631.22 KFQ96591.1 - 3.7e-18 65.3 0.0 4e-18 65.2 0.0 1.0 1 0 0 1 1 1 1 GGL domain DUF3294 PF07957.11 KFQ96591.1 - 0.036 13.8 0.7 0.041 13.6 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) Abi_HHR PF07815.14 KFQ96592.1 - 2.1e-18 66.2 0.0 3.6e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Abl-interactor HHR SH3_9 PF14604.6 KFQ96592.1 - 4.6e-15 55.2 0.2 1.2e-14 53.9 0.1 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFQ96592.1 - 4.3e-10 39.1 0.0 6.9e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFQ96592.1 - 8e-06 25.5 0.0 1.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Put_Phosphatase PF06888.12 KFQ96593.1 - 6.6e-100 333.3 0.0 7.4e-100 333.2 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 KFQ96593.1 - 1.1e-08 35.7 0.0 1.7e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFQ96593.1 - 0.0015 18.9 0.0 0.17 12.1 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFQ96593.1 - 0.0034 17.5 0.1 0.31 11.1 0.1 2.5 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase PNK3P PF08645.11 KFQ96593.1 - 0.0076 16.0 0.1 2.6 7.7 0.0 2.4 2 1 0 2 2 2 2 Polynucleotide kinase 3 phosphatase zf-C2H2 PF00096.26 KFQ96594.1 - 4.3e-31 105.6 58.4 1.2e-05 25.5 1.5 9.4 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ96594.1 - 4.5e-26 90.1 66.8 1.3e-07 31.7 1.3 9.7 9 1 0 9 9 9 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ96594.1 - 3.4e-23 80.3 57.7 9e-05 23.0 0.8 9.3 9 0 0 9 9 9 7 C2H2-type zinc finger zf-met PF12874.7 KFQ96594.1 - 4.1e-11 42.9 39.3 0.0018 18.6 0.1 8.0 8 0 0 8 8 7 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFQ96594.1 - 1.8e-09 37.6 38.7 0.043 14.1 0.0 7.5 8 0 0 8 8 7 5 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFQ96594.1 - 0.00047 19.9 27.9 0.11 12.3 0.7 6.9 7 0 0 7 7 7 3 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFQ96594.1 - 0.0014 18.5 52.4 0.0089 16.0 0.2 8.7 9 0 0 9 9 9 5 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFQ96594.1 - 0.0021 17.9 37.8 0.87 9.6 0.0 8.0 8 0 0 8 8 8 3 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KFQ96594.1 - 0.0027 17.2 29.0 3.1 7.5 0.1 8.2 8 0 0 8 8 8 2 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 KFQ96594.1 - 0.0082 16.4 1.3 0.0082 16.4 1.3 5.2 3 3 2 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding ADK_lid PF05191.14 KFQ96594.1 - 0.011 15.7 21.9 0.016 15.2 0.5 5.4 4 1 1 5 5 5 0 Adenylate kinase, active site lid BolA PF01722.18 KFQ96594.1 - 0.02 15.1 6.4 0.63 10.4 0.1 3.8 2 2 1 4 4 4 0 BolA-like protein zf-C2H2_2 PF12756.7 KFQ96594.1 - 0.024 15.0 46.6 0.5 10.7 1.9 6.1 1 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) SDA1 PF05285.12 KFQ96594.1 - 0.038 13.4 22.6 0.055 12.9 22.6 1.2 1 0 0 1 1 1 0 SDA1 zf_C2H2_13 PF18508.1 KFQ96594.1 - 0.19 11.3 6.2 6 6.5 0.1 4.7 4 0 0 4 4 4 0 Zinc finger domain Prim_Zn_Ribbon PF08273.12 KFQ96594.1 - 0.3 11.4 0.2 0.3 11.4 0.2 3.8 5 0 0 5 5 4 0 Zinc-binding domain of primase-helicase BUD22 PF09073.10 KFQ96594.1 - 0.31 10.3 26.7 0.46 9.8 26.7 1.1 1 0 0 1 1 1 0 BUD22 zf-C2H2_3rep PF18868.1 KFQ96594.1 - 0.34 11.6 0.2 0.34 11.6 0.2 7.4 2 1 5 7 7 6 0 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 KFQ96594.1 - 0.88 9.7 37.3 0.8 9.9 1.2 6.6 4 3 3 7 7 7 0 Zinc ribbon domain DUF2502 PF10697.9 KFQ96594.1 - 1.1 9.6 0.0 1.1 9.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2502) PriA_CRR PF18319.1 KFQ96594.1 - 2.4 8.2 6.2 6.1 6.9 0.7 4.2 3 0 0 3 3 3 0 PriA DNA helicase Cys-rich region (CRR) domain zf_C2H2_ZHX PF18387.1 KFQ96594.1 - 5.5 6.7 17.7 1.8 8.2 0.2 4.7 3 1 2 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain HNH_5 PF14279.6 KFQ96594.1 - 6.9 6.6 25.3 2.6 8.0 0.5 6.8 5 3 1 6 6 6 0 HNH endonuclease zf-ribbon_3 PF13248.6 KFQ96594.1 - 8.8 5.9 15.5 4.4 6.8 0.1 5.8 6 0 0 6 6 6 0 zinc-ribbon domain Band_7 PF01145.25 KFQ96595.1 - 1.1e-25 90.7 0.9 1.5e-25 90.2 0.9 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.8 KFQ96595.1 - 0.0049 17.0 0.4 0.0081 16.3 0.4 1.4 1 0 0 1 1 1 1 Mediator complex subunit 2 Peptidase_S66 PF02016.15 KFQ96595.1 - 0.037 14.2 0.0 0.68 10.1 0.0 2.2 2 0 0 2 2 2 0 LD-carboxypeptidase N-terminal domain TNFR_c6 PF00020.18 KFQ96596.1 - 2.9e-27 94.8 46.9 3.4e-11 43.4 5.7 4.3 3 1 0 4 4 4 4 TNFR/NGFR cysteine-rich region Death PF00531.22 KFQ96597.1 - 4.8e-16 58.7 0.6 5.4e-16 58.5 0.6 1.0 1 0 0 1 1 1 1 Death domain FtsX_ECD PF18075.1 KFQ96597.1 - 0.088 13.4 0.1 0.13 12.9 0.1 1.4 1 1 0 1 1 1 0 FtsX extracellular domain Eno-Rase_FAD_bd PF07055.12 KFQ96597.1 - 0.15 12.5 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain Neurexophilin PF06312.12 KFQ96598.1 - 7.5e-104 345.8 1.6 8.3e-104 345.6 1.6 1.0 1 0 0 1 1 1 1 Neurexophilin Filamin PF00630.19 KFQ96598.1 - 0.0096 16.7 0.5 0.79 10.6 0.0 2.2 1 1 1 2 2 2 2 Filamin/ABP280 repeat UAA PF08449.11 KFQ96599.1 - 2e-50 171.7 7.0 2.6e-50 171.3 7.0 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 KFQ96599.1 - 6.4e-14 52.0 4.8 3.2e-08 33.3 1.2 2.0 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 KFQ96599.1 - 7.2e-14 52.1 18.9 2.6e-08 34.2 12.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 KFQ96599.1 - 8.4e-05 21.7 4.5 0.0059 15.6 0.0 2.1 1 1 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 KFQ96599.1 - 0.011 14.9 2.1 0.17 11.0 2.2 2.1 1 1 0 1 1 1 0 Nucleotide-sugar transporter FAM117 PF15388.6 KFQ96600.1 - 3.2e-121 404.6 5.9 3.6e-121 404.4 5.9 1.0 1 0 0 1 1 1 1 Protein Family FAM117 CSTF_C PF14304.6 KFQ96600.1 - 0.34 10.5 4.3 0.58 9.8 0.8 2.3 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal MOZ_SAS PF01853.18 KFQ96601.1 - 2.7e-86 287.8 1.4 4.3e-86 287.1 1.4 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KFQ96601.1 - 2.1e-23 81.6 1.6 2.1e-23 81.6 1.6 2.4 3 0 0 3 3 3 1 MYST family zinc finger domain zf-C2HC PF01530.18 KFQ96601.1 - 2.7e-06 27.5 3.2 2.8e-06 27.4 1.3 2.0 2 0 0 2 2 2 1 Zinc finger, C2HC type Acetyltransf_7 PF13508.7 KFQ96601.1 - 0.023 15.1 0.0 0.047 14.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-met PF12874.7 KFQ96601.1 - 0.031 14.7 0.4 0.081 13.3 0.4 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DLL_N PF12413.8 KFQ96602.1 - 9.7e-23 81.2 16.7 1.8e-22 80.4 16.7 1.5 1 0 0 1 1 1 1 Homeobox protein distal-less-like N terminal Homeodomain PF00046.29 KFQ96602.1 - 5.8e-22 77.3 3.1 1e-21 76.5 3.1 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ96602.1 - 0.0017 18.2 0.3 0.0031 17.4 0.3 1.4 1 0 0 1 1 1 1 Homeobox KN domain DUF4292 PF14125.6 KFQ96602.1 - 0.029 14.1 0.5 2.3 7.9 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4292) YdaS_antitoxin PF15943.5 KFQ96602.1 - 0.034 14.0 0.1 0.061 13.2 0.1 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT FG-GAP PF01839.23 KFQ96603.1 - 0.00016 21.7 3.5 0.00038 20.5 0.3 2.3 2 1 0 2 2 2 1 FG-GAP repeat FG-GAP_2 PF14312.6 KFQ96603.1 - 0.075 13.3 4.0 0.35 11.1 0.4 2.1 2 0 0 2 2 2 0 FG-GAP repeat VCBS PF13517.6 KFQ96603.1 - 0.11 13.1 0.0 0.13 12.9 0.0 1.1 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella SAM_2 PF07647.17 KFQ96604.1 - 5.6e-14 52.0 0.0 9e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFQ96604.1 - 4.5e-13 49.4 0.0 7.8e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Sarcoglycan_2 PF05510.13 KFQ96605.1 - 1e-60 205.6 0.0 1.5e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon COLFI PF01410.18 KFQ96606.1 - 1.1e-56 191.8 0.0 1.2e-56 191.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Collagen PF01391.18 KFQ96607.1 - 1.1e-13 50.7 32.0 1.6e-11 43.8 32.0 2.0 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Guanylate_kin PF00625.21 KFQ96609.1 - 5.3e-48 163.1 0.0 9.5e-48 162.3 0.0 1.4 1 1 0 1 1 1 1 Guanylate kinase L27 PF02828.16 KFQ96609.1 - 9.5e-23 79.7 0.3 5.4e-16 58.1 0.5 2.6 2 0 0 2 2 2 2 L27 domain PDZ PF00595.24 KFQ96609.1 - 1.1e-07 32.1 0.3 2.4e-07 31.0 0.3 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFQ96609.1 - 0.00047 20.4 0.0 0.001 19.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFQ96609.1 - 0.0027 17.5 0.6 0.012 15.4 0.2 2.3 2 0 0 2 2 2 1 PDZ domain RsgA_GTPase PF03193.16 KFQ96609.1 - 0.099 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Hormone_3 PF00159.18 KFQ96610.1 - 2.1e-21 75.7 0.3 5.3e-21 74.4 0.2 1.6 2 0 0 2 2 2 1 Pancreatic hormone peptide AD PF09793.9 KFQ96611.1 - 1.8e-25 88.9 0.6 2.2e-25 88.6 0.6 1.1 1 0 0 1 1 1 1 Anticodon-binding domain Hist_deacetyl PF00850.19 KFQ96612.1 - 2.5e-19 69.9 0.2 2.6e-19 69.8 0.2 1.0 1 0 0 1 1 1 1 Histone deacetylase domain ubiquitin PF00240.23 KFQ96613.1 - 4e-09 36.1 0.0 5.4e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Sgf11 PF08209.11 KFQ96614.1 - 2.2e-18 65.5 2.7 4e-18 64.7 2.7 1.5 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) SCA7 PF08313.12 KFQ96614.1 - 7.9e-08 32.1 1.6 1.9e-07 30.8 1.6 1.6 1 0 0 1 1 1 1 SCA7, zinc-binding domain S_100 PF01023.19 KFQ96614.1 - 0.018 14.8 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain zf-C2HC_2 PF13913.6 KFQ96614.1 - 0.021 14.7 1.1 0.053 13.4 1.1 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Mito_carr PF00153.27 KFQ96615.1 - 1.1e-64 214.3 0.3 2.5e-21 75.4 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFQ96615.1 - 0.13 11.4 0.1 0.53 9.4 0.1 1.9 1 1 0 1 1 1 0 Gammaproteobacterial serine protease RIIa PF02197.17 KFQ96615.1 - 0.19 11.4 0.7 0.41 10.4 0.7 1.6 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Tubulin-binding PF00418.19 KFQ96616.1 - 1.5e-59 197.7 30.1 3e-16 59.1 3.1 5.7 5 0 0 5 5 5 5 Tau and MAP protein, tubulin-binding repeat Tmemb_cc2 PF10267.9 KFQ96616.1 - 1.5 7.8 10.7 0.8 8.8 0.5 2.8 2 1 1 3 3 3 0 Predicted transmembrane and coiled-coil 2 protein PEHE PF15275.6 KFQ96617.1 - 4.7e-15 56.4 1.9 3.8e-14 53.4 0.0 3.2 2 0 0 2 2 2 1 PEHE domain TPR_1 PF00515.28 KFQ96618.1 - 6.7e-46 152.3 13.9 1.2e-09 37.5 0.2 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ96618.1 - 7.1e-33 110.1 14.8 6.4e-06 25.9 0.1 9.6 9 0 0 9 9 9 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ96618.1 - 6.8e-32 109.5 26.1 1.7e-22 79.4 5.7 5.5 3 1 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KFQ96618.1 - 5.1e-29 98.0 10.2 0.00014 21.8 0.2 9.4 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ96618.1 - 9.8e-27 93.1 4.9 3.2e-07 30.5 0.0 7.1 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ96618.1 - 8.6e-25 86.2 13.9 9.3e-07 28.4 0.1 8.5 4 2 5 9 9 8 5 TPR repeat TPR_17 PF13431.6 KFQ96618.1 - 7.9e-23 79.1 9.0 0.0038 17.5 0.0 9.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ96618.1 - 4e-20 72.1 4.7 0.082 13.4 0.0 7.7 5 1 3 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ96618.1 - 9.1e-19 67.8 0.0 6e-08 33.2 0.0 6.0 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ96618.1 - 1.6e-16 59.6 0.1 0.011 16.5 0.0 8.6 4 1 5 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFQ96618.1 - 1.5e-13 50.4 9.0 0.17 12.6 0.0 8.3 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFQ96618.1 - 9.8e-12 44.9 0.0 4.7e-05 23.5 0.0 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ96618.1 - 8.7e-07 28.6 2.7 4.2 7.6 0.0 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat ChAPs PF09295.10 KFQ96618.1 - 1.4e-06 27.6 0.9 0.0019 17.3 0.0 2.3 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.6 KFQ96618.1 - 1.8e-05 24.1 0.0 1.1 8.4 0.0 4.5 3 1 1 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFQ96618.1 - 0.00013 21.5 0.2 0.2 11.0 0.0 3.3 2 1 1 3 3 3 1 MalT-like TPR region TPR_20 PF14561.6 KFQ96618.1 - 0.0079 16.5 0.7 0.14 12.5 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 KFQ96618.1 - 0.015 15.1 0.0 0.31 10.7 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 KFQ96618.1 - 0.022 14.6 2.9 4.9 7.2 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Cas_Cas02710 PF09670.10 KFQ96618.1 - 0.032 13.1 0.1 0.11 11.2 0.0 1.9 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas02710) PPTA PF01239.22 KFQ96618.1 - 0.1 12.4 2.4 1.5 8.7 0.2 2.8 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat SRP_TPR_like PF17004.5 KFQ96618.1 - 0.1 12.6 7.7 7 6.7 0.4 3.7 3 1 1 4 4 4 0 Putative TPR-like repeat DUF2225 PF09986.9 KFQ96618.1 - 2.7 7.7 7.6 1.5 8.5 0.2 3.2 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) EF-hand_6 PF13405.6 KFQ96619.1 - 3e-09 36.1 0.0 0.00074 19.3 0.0 3.7 4 1 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KFQ96619.1 - 6.4e-05 22.2 2.0 0.11 12.1 0.0 4.2 4 1 1 5 5 5 1 EF hand EF-hand_9 PF14658.6 KFQ96619.1 - 0.0004 20.6 0.0 0.37 11.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KFQ96619.1 - 0.0015 18.9 0.1 0.01 16.3 0.0 2.2 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 KFQ96619.1 - 0.14 12.0 1.2 14 5.6 0.1 2.9 1 1 1 2 2 2 0 EF-hand domain pair 7tm_2 PF00002.24 KFQ96620.1 - 3.3e-84 282.0 18.9 4.1e-84 281.7 18.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFQ96620.1 - 3.1e-16 59.4 3.5 6.6e-16 58.4 3.5 1.5 1 0 0 1 1 1 1 Hormone receptor domain DUF1682 PF07946.14 KFQ96621.1 - 1.1e-91 307.5 5.6 1.1e-91 307.5 5.6 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1682) zf-CCCH PF00642.24 KFQ96622.1 - 5e-09 35.8 2.7 5e-09 35.8 2.7 2.3 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KFQ96622.1 - 1.1e-08 34.7 8.4 2.3e-08 33.8 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFQ96622.1 - 1.1e-07 31.5 9.5 2.4e-07 30.5 9.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ96622.1 - 5.2e-06 26.2 10.2 1.2e-05 25.0 10.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFQ96622.1 - 1.6e-05 24.8 12.4 3.3e-05 23.7 12.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFQ96622.1 - 1.6e-05 25.2 9.7 3.5e-05 24.0 9.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf_CCCH_4 PF18345.1 KFQ96622.1 - 5.4e-05 23.1 4.4 5.4e-05 23.1 4.4 2.1 2 0 0 2 2 2 1 Zinc finger domain zf-RING_UBOX PF13445.6 KFQ96622.1 - 8.2e-05 22.6 9.5 0.0002 21.3 9.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-CCCH_4 PF18044.1 KFQ96622.1 - 0.00038 20.2 2.7 0.00038 20.2 2.7 2.5 2 0 0 2 2 2 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 KFQ96622.1 - 0.00042 20.1 7.3 0.00081 19.2 7.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFQ96622.1 - 0.0048 17.0 9.0 0.0048 17.0 9.0 1.8 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KFQ96622.1 - 0.013 15.6 6.9 0.013 15.6 6.9 1.9 2 0 0 2 2 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 KFQ96622.1 - 0.015 15.1 3.8 0.036 13.9 3.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Pannexin_like PF12534.8 KFQ96622.1 - 0.045 12.8 0.8 0.084 12.0 0.8 1.4 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 zf-P11 PF03854.14 KFQ96622.1 - 0.13 11.9 6.8 0.24 11.1 6.8 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-CCCH_2 PF14608.6 KFQ96622.1 - 1.1 9.8 7.7 0.1 13.1 2.5 2.1 2 0 0 2 2 1 0 RNA-binding, Nab2-type zinc finger LIM PF00412.22 KFQ96623.1 - 3e-10 40.1 10.8 3.5e-10 40.0 10.8 1.0 1 0 0 1 1 1 1 LIM domain zf-SNAP50_C PF12251.8 KFQ96623.1 - 0.094 12.4 7.1 0.11 12.2 7.1 1.1 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal Ephrin_rec_like PF07699.13 KFQ96624.1 - 0.0012 18.5 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 Putative ephrin-receptor like Comm PF15957.5 KFQ96624.1 - 0.094 13.1 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Commissureless Ig_2 PF13895.6 KFQ96625.1 - 0.00023 21.4 0.0 0.00041 20.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFQ96625.1 - 0.015 15.9 0.0 0.027 15.1 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Izumo-Ig PF16706.5 KFQ96625.1 - 0.024 14.7 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain I-set PF07679.16 KFQ96625.1 - 0.04 14.0 0.0 0.078 13.1 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain Sp38 PF07354.12 KFQ96625.1 - 0.056 12.9 0.4 0.078 12.4 0.4 1.2 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) V-set PF07686.17 KFQ96625.1 - 0.12 12.6 0.0 0.35 11.1 0.0 1.7 1 1 1 2 2 2 0 Immunoglobulin V-set domain 7tm_2 PF00002.24 KFQ96626.1 - 2e-75 253.2 21.9 2.5e-75 252.9 21.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFQ96626.1 - 2e-16 60.0 1.2 4.4e-16 58.9 1.2 1.6 1 0 0 1 1 1 1 Hormone receptor domain DUF2976 PF11190.8 KFQ96626.1 - 0.13 12.0 1.2 16 5.4 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) DUF4574 PF15141.6 KFQ96626.1 - 0.18 11.8 0.3 19 5.3 0.1 2.6 1 1 1 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 ASC PF00858.24 KFQ96627.1 - 7.9e-20 71.2 0.0 8.8e-20 71.1 0.0 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.24 KFQ96629.1 - 3.3e-98 329.5 0.5 9.5e-98 328.0 0.5 1.6 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel SWIB PF02201.18 KFQ96630.1 - 6.2e-21 74.1 0.1 1.7e-20 72.6 0.1 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain UBA2_C PF16195.5 KFQ96631.1 - 0.00012 22.7 8.9 0.00027 21.5 1.8 2.2 2 0 0 2 2 2 2 SUMO-activating enzyme subunit 2 C-terminus DUF3458 PF11940.8 KFQ96631.1 - 0.18 12.3 0.8 0.57 10.7 0.0 2.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3458) Ig-like fold Rtf2 PF04641.12 KFQ96631.1 - 0.45 9.8 12.4 0.31 10.4 0.3 2.0 1 1 0 2 2 2 0 Rtf2 RING-finger TED_complement PF07678.14 KFQ96632.1 - 2e-105 352.3 0.8 2.8e-105 351.8 0.8 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M PF00207.22 KFQ96632.1 - 1.7e-25 88.7 0.1 8.3e-25 86.5 0.1 2.2 2 0 0 2 2 2 1 Alpha-2-macroglobulin family A2M_BRD PF07703.14 KFQ96632.1 - 2.5e-21 76.5 0.0 9.4e-21 74.6 0.0 2.1 1 0 0 1 1 1 1 Alpha-2-macroglobulin bait region domain SVA PF05326.11 KFQ96632.1 - 6.5e-11 42.3 0.0 1.4e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Seminal vesicle autoantigen (SVA) SQHop_cyclase_N PF13249.6 KFQ96632.1 - 0.0057 15.8 0.1 1.3 8.0 0.0 2.5 2 1 0 2 2 2 2 Squalene-hopene cyclase N-terminal domain A2M_recep PF07677.14 KFQ96632.1 - 0.0097 16.6 0.0 0.02 15.6 0.0 1.6 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain Prenyltrans PF00432.21 KFQ96632.1 - 0.022 14.5 0.1 0.14 12.0 0.0 2.4 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat Acyltransferase PF01553.21 KFQ96633.1 - 4.7e-32 110.4 0.1 7.2e-32 109.8 0.1 1.3 1 0 0 1 1 1 1 Acyltransferase 7tm_2 PF00002.24 KFQ96634.1 - 2.6e-84 282.4 18.3 4e-84 281.7 18.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFQ96634.1 - 2.2e-16 59.9 3.1 2.2e-16 59.9 3.1 2.2 3 0 0 3 3 3 1 Hormone receptor domain DUF2628 PF10947.8 KFQ96634.1 - 0.37 11.2 9.4 0.035 14.5 4.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) DUF4418 PF14387.6 KFQ96634.1 - 0.4 10.9 6.5 0.039 14.2 1.9 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4418) Ion_trans PF00520.31 KFQ96635.1 - 6.3e-250 824.7 109.1 1.5e-77 260.1 17.8 4.1 4 0 0 4 4 4 4 Ion transport protein Na_trans_assoc PF06512.13 KFQ96635.1 - 1.6e-57 195.1 2.7 2.7e-57 194.3 1.1 2.1 2 0 0 2 2 2 1 Sodium ion transport-associated PKD_channel PF08016.12 KFQ96635.1 - 2.9e-08 32.8 87.9 4.3e-05 22.4 0.2 9.5 6 4 4 10 10 10 7 Polycystin cation channel IQ PF00612.27 KFQ96635.1 - 0.00037 20.0 0.8 0.001 18.7 0.8 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif GPHH PF16905.5 KFQ96635.1 - 0.00045 19.9 0.0 0.00087 19.0 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Hormone_1 PF00103.20 KFQ96636.1 - 5.1e-15 55.8 0.0 5.5e-15 55.7 0.0 1.0 1 0 0 1 1 1 1 Somatotropin hormone family Rad52_Rad22 PF04098.15 KFQ96637.1 - 1.6e-08 34.6 0.0 2.1e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein RRM_1 PF00076.22 KFQ96637.1 - 2e-05 24.3 0.2 9.4e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RUN PF02759.19 KFQ96639.1 - 2e-11 44.0 0.1 2e-11 44.0 0.1 1.4 2 0 0 2 2 2 1 RUN domain zf-RING_9 PF13901.6 KFQ96640.1 - 3.7e-58 196.9 3.8 7.5e-58 195.9 3.8 1.5 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon PH PF00169.29 KFQ96640.1 - 1.4e-10 41.7 0.0 4.5e-06 27.1 0.0 2.5 2 0 0 2 2 2 2 PH domain zf-RRN7 PF11781.8 KFQ96640.1 - 0.0095 15.6 3.3 0.5 10.1 1.6 2.7 2 0 0 2 2 2 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 PH_13 PF16652.5 KFQ96640.1 - 0.05 13.4 0.0 4.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain FYVE_2 PF02318.16 KFQ96640.1 - 1.3 9.3 5.0 4.4 7.6 1.3 2.7 2 1 0 2 2 2 0 FYVE-type zinc finger Prok-RING_2 PF14445.6 KFQ96640.1 - 3.6 7.8 9.9 2.2 8.5 0.6 3.5 3 1 0 3 3 3 0 Prokaryotic RING finger family 2 SH3_9 PF14604.6 KFQ96641.1 - 0.0018 18.1 0.0 0.0019 18.0 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFQ96641.1 - 0.015 14.9 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 SH3 domain RhoGAP PF00620.27 KFQ96642.1 - 4.7e-36 123.9 0.0 6e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain GCIP PF13324.6 KFQ96643.1 - 4.9e-05 23.1 0.0 6.6e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting FAM163 PF15069.6 KFQ96643.1 - 0.0011 19.4 0.0 0.0013 19.2 0.0 1.2 1 0 0 1 1 1 1 FAM163 family Cadherin_C_2 PF16492.5 KFQ96643.1 - 0.0095 16.7 0.1 0.018 15.8 0.0 1.5 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal Granulin PF00396.18 KFQ96644.1 - 7.5e-37 125.4 96.6 8.7e-16 58.0 22.1 6.8 6 1 1 7 7 7 5 Granulin Lustrin_cystein PF14625.6 KFQ96644.1 - 0.051 13.9 6.3 0.051 13.9 6.3 6.5 5 2 1 7 7 7 0 Lustrin, cysteine-rich repeated domain DC_STAMP PF07782.13 KFQ96646.1 - 5.4e-53 179.7 0.0 2.5e-52 177.5 0.0 2.1 2 0 0 2 2 2 1 DC-STAMP-like protein PEHE PF15275.6 KFQ96648.1 - 2.1e-27 96.3 1.5 2.1e-27 96.3 1.5 2.1 3 0 0 3 3 3 1 PEHE domain tRNA-synt_1c PF00749.21 KFQ96648.1 - 0.11 11.3 0.1 0.18 10.7 0.1 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain zf-C4 PF00105.18 KFQ96649.1 - 6.3e-30 103.5 18.0 1.1e-29 102.6 18.0 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFQ96649.1 - 1.6e-08 34.4 0.4 1.3e-07 31.4 0.1 2.4 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor DUF3921 PF13060.6 KFQ96649.1 - 0.16 12.0 0.0 6 7.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3921) V-set PF07686.17 KFQ96652.1 - 6.7e-08 32.7 0.1 6.7e-08 32.7 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFQ96652.1 - 3.4e-05 23.8 0.0 3.4e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ96652.1 - 4.1e-05 24.1 0.0 4.6e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFQ96652.1 - 0.00051 20.2 0.1 0.00052 20.1 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 KFQ96652.1 - 0.0046 16.5 0.0 0.0048 16.4 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set_CD47 PF08204.11 KFQ96652.1 - 0.009 16.0 0.0 0.009 16.0 0.0 1.0 1 0 0 1 1 1 1 CD47 immunoglobulin-like domain Herpes_gE PF02480.16 KFQ96652.1 - 0.014 14.1 0.0 0.016 14.0 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Ig_2 PF13895.6 KFQ96652.1 - 0.028 14.8 0.0 0.028 14.8 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain Izumo-Ig PF16706.5 KFQ96652.1 - 0.037 14.1 0.0 0.038 14.1 0.0 1.1 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Ig_3 PF13927.6 KFQ96653.1 - 0.017 15.7 0.0 0.017 15.7 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KFQ96653.1 - 0.025 14.7 0.0 0.025 14.7 0.0 1.0 1 0 0 1 1 1 0 Immunoglobulin V-set domain V-set PF07686.17 KFQ96654.1 - 3.1e-14 53.0 0.7 3.6e-12 46.4 0.0 2.3 2 1 0 2 2 2 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFQ96654.1 - 7.4e-13 48.9 1.1 5.5e-07 30.1 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFQ96654.1 - 4.9e-09 36.1 1.5 0.00041 20.4 0.0 2.8 2 2 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFQ96654.1 - 1.4e-07 31.6 3.3 5.8e-05 23.2 0.1 2.7 2 2 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.15 KFQ96654.1 - 8e-07 29.4 1.5 0.00012 22.4 0.0 3.0 2 1 0 2 2 2 1 Immunoglobulin C1-set domain Ig_2 PF13895.6 KFQ96654.1 - 1e-06 28.9 1.2 0.033 14.5 0.1 3.3 2 2 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFQ96654.1 - 1.4e-05 25.1 0.1 2.5e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.11 KFQ96654.1 - 3.5e-05 23.8 0.1 7.8e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 CD47 immunoglobulin-like domain GPP34 PF05719.11 KFQ96656.1 - 2.2e-60 204.2 1.8 2.8e-60 203.9 1.8 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Peptidase_M15_2 PF05951.13 KFQ96656.1 - 0.039 13.6 0.1 0.071 12.8 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) DZF PF07528.14 KFQ96658.1 - 2.9e-65 220.4 0.0 5.1e-65 219.6 0.0 1.4 1 0 0 1 1 1 1 DZF domain zf-met PF12874.7 KFQ96658.1 - 6.7e-22 77.2 15.3 1.5e-06 28.4 2.2 3.6 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFQ96658.1 - 4.6e-14 52.3 18.5 0.00023 21.4 2.4 4.3 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFQ96658.1 - 0.0042 17.4 17.2 0.96 9.8 0.4 4.1 3 1 1 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.12 KFQ96658.1 - 0.083 12.7 18.3 0.33 10.7 2.6 3.5 3 0 0 3 3 3 0 U1 zinc finger zf-C2H2_4 PF13894.6 KFQ96658.1 - 1.2 10.2 10.7 12 7.0 1.4 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KFQ96658.1 - 2.6 8.7 6.0 1.4 9.7 0.1 2.9 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats LPD38 PF18857.1 KFQ96658.1 - 2.7 8.1 6.7 3.6 7.7 1.4 2.5 2 0 0 2 2 2 0 Large polyvalent protein associated domain 38 zf-C2H2 PF00096.26 KFQ96658.1 - 4.1 8.1 15.5 4.9 7.8 0.1 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type PC4 PF02229.16 KFQ96659.1 - 5.6e-05 22.7 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) QLQ PF08880.11 KFQ96659.1 - 0.021 14.6 0.2 0.038 13.7 0.2 1.5 1 0 0 1 1 1 0 QLQ ANF_receptor PF01094.28 KFQ96660.1 - 1.9e-24 86.4 0.1 2.3e-24 86.2 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region DUF4690 PF15756.5 KFQ96660.1 - 0.048 14.3 0.0 0.092 13.4 0.0 1.4 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Arf PF00025.21 KFQ96661.1 - 1.9e-64 216.3 0.9 2.1e-64 216.2 0.9 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFQ96661.1 - 2.4e-15 56.8 0.3 3.2e-15 56.4 0.3 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFQ96661.1 - 3.3e-14 52.8 0.4 3.6e-14 52.7 0.4 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFQ96661.1 - 3.5e-12 46.1 0.2 4.3e-12 45.8 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFQ96661.1 - 1.1e-08 34.7 1.5 1.6e-06 27.5 0.6 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KFQ96661.1 - 2.7e-07 30.6 0.1 3.8e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFQ96661.1 - 5.8e-07 29.1 0.4 6.9e-07 28.9 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFQ96661.1 - 0.0031 17.1 0.4 0.016 14.8 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 KFQ96661.1 - 0.021 14.8 0.2 0.079 13.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KFQ96661.1 - 0.037 13.5 0.9 0.2 11.2 0.8 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B TPM_phosphatase PF04536.14 KFQ96661.1 - 0.072 13.3 0.2 0.16 12.1 0.1 1.7 1 1 1 2 2 2 0 TPM domain Guanylate_kin PF00625.21 KFQ96662.1 - 1.1e-47 162.1 0.2 1.8e-47 161.4 0.2 1.4 1 0 0 1 1 1 1 Guanylate kinase VGCC_beta4Aa_N PF12052.8 KFQ96662.1 - 1.5e-22 79.4 6.3 3.5e-22 78.2 6.3 1.7 1 0 0 1 1 1 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal SH3_1 PF00018.28 KFQ96662.1 - 0.001 18.6 0.0 0.0047 16.5 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFQ96662.1 - 0.053 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain SH3_9 PF14604.6 KFQ96662.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain FH2 PF02181.23 KFQ96663.1 - 9.2e-103 344.2 10.6 9.2e-103 344.2 10.6 3.4 5 0 0 5 5 5 2 Formin Homology 2 Domain Drf_FH3 PF06367.16 KFQ96663.1 - 1.1e-49 168.7 16.1 1.1e-49 168.7 16.1 2.8 3 0 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 KFQ96663.1 - 1.3e-22 80.3 3.1 2.3e-13 50.2 0.5 5.3 4 1 1 5 5 5 2 Diaphanous GTPase-binding Domain DsrC PF04358.13 KFQ96663.1 - 0.38 11.3 4.2 0.54 10.8 1.5 2.7 2 0 0 2 2 2 0 DsrC like protein Cob_adeno_trans PF01923.18 KFQ96663.1 - 2.9 8.0 6.9 28 4.8 6.4 2.7 1 1 0 1 1 1 0 Cobalamin adenosyltransferase FF PF01846.19 KFQ96664.1 - 5.4e-47 157.8 23.7 3.4e-16 59.1 0.5 6.2 5 0 0 5 5 5 5 FF domain WW PF00397.26 KFQ96664.1 - 1.8e-19 69.5 19.5 2.9e-10 40.1 8.0 2.7 2 0 0 2 2 2 2 WW domain LUD_dom PF02589.15 KFQ96664.1 - 1.6 8.4 7.2 1.4 8.6 1.2 3.1 3 0 0 3 3 3 0 LUD domain Glyco_hyd_101C PF17451.2 KFQ96664.1 - 4 7.8 15.0 5.4 7.3 2.3 3.8 2 1 1 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain TPR_6 PF13174.6 KFQ96664.1 - 4.9 8.0 5.0 29 5.6 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Glycos_transf_2 PF00535.26 KFQ96665.1 - 4.1e-36 124.3 0.0 6.7e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFQ96665.1 - 1.3e-30 106.2 1.4 2e-30 105.6 1.4 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 KFQ96665.1 - 3.5e-07 30.4 0.0 6.8e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KFQ96665.1 - 1e-05 25.1 0.1 2.1e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KFQ96665.1 - 2.1e-05 24.2 0.0 4.6e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.6 KFQ96665.1 - 0.00023 21.8 0.0 0.36 11.6 0.0 2.6 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like IRK_C PF17655.1 KFQ96666.1 - 2.6e-70 235.5 0.0 3.2e-70 235.2 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFQ96666.1 - 5.3e-58 194.8 0.9 7.4e-58 194.4 0.9 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 KFQ96666.1 - 9.9 6.2 12.6 63 3.6 12.6 2.2 1 1 0 1 1 1 0 Ion channel DAO PF01266.24 KFQ96667.1 - 1.5e-52 179.3 0.0 2e-52 178.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KFQ96667.1 - 7.1e-42 142.2 0.1 1.6e-41 141.1 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase EF-hand_7 PF13499.6 KFQ96667.1 - 1.1e-11 45.0 0.5 2.3e-11 44.0 0.5 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFQ96667.1 - 2e-10 39.5 0.7 0.00017 20.9 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFQ96667.1 - 1.8e-09 36.8 0.4 0.00019 21.1 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain FAD_binding_2 PF00890.24 KFQ96667.1 - 4.8e-08 32.5 0.2 1.3e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 KFQ96667.1 - 2.7e-06 26.7 0.0 0.00074 18.7 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 KFQ96667.1 - 3.1e-06 26.8 0.1 2.8e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase EF-hand_5 PF13202.6 KFQ96667.1 - 7.8e-05 22.0 1.5 0.1 12.2 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFQ96667.1 - 8.4e-05 22.3 0.0 0.00024 20.9 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair Pyr_redox_2 PF07992.14 KFQ96667.1 - 8.4e-05 21.9 0.4 0.0023 17.2 0.0 3.1 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_9 PF14658.6 KFQ96667.1 - 0.00084 19.6 0.0 0.002 18.4 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain NAD_binding_8 PF13450.6 KFQ96667.1 - 0.0022 18.2 0.2 0.012 15.9 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KFQ96667.1 - 0.0038 16.0 0.0 0.006 15.3 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KFQ96667.1 - 0.005 16.1 0.0 0.037 13.3 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFQ96667.1 - 0.019 14.2 0.0 0.058 12.6 0.0 1.8 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 KFQ96667.1 - 0.053 12.7 0.0 0.31 10.2 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 KFQ96667.1 - 0.055 14.0 0.3 0.32 11.6 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase BUD22 PF09073.10 KFQ96668.1 - 0.31 10.3 19.8 0.38 10.0 19.8 1.1 1 0 0 1 1 1 0 BUD22 Pkinase PF00069.25 KFQ96669.1 - 1e-31 110.3 0.0 2.5e-31 109.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ96669.1 - 1.5e-31 109.6 0.0 5.1e-15 55.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase TGF_beta_GS PF08515.12 KFQ96669.1 - 3e-17 61.8 0.4 5.5e-17 61.0 0.4 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.23 KFQ96669.1 - 7e-06 27.0 15.6 7e-06 27.0 15.6 2.3 3 0 0 3 3 3 1 Activin types I and II receptor domain Pkinase_fungal PF17667.1 KFQ96669.1 - 0.0017 17.2 0.2 0.0065 15.3 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase zf-RING_12 PF17976.1 KFQ96669.1 - 0.025 14.8 3.3 0.071 13.4 2.8 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain APH PF01636.23 KFQ96669.1 - 0.088 12.7 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KFQ96670.1 - 9.9e-36 123.3 0.0 1.5e-35 122.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ96670.1 - 1.5e-35 122.9 0.0 2.3e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.12 KFQ96670.1 - 1.9e-17 62.4 0.4 3.4e-17 61.6 0.4 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif APH PF01636.23 KFQ96670.1 - 0.0018 18.2 0.1 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFQ96670.1 - 0.0036 16.3 0.1 0.007 15.3 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KFQ96670.1 - 0.028 14.0 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 TMEM154 PF15102.6 KFQ96670.1 - 0.12 12.3 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family PSI_PsaJ PF01701.18 KFQ96670.1 - 1.8 9.2 3.6 4.4 7.9 3.6 1.6 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ PNP_UDP_1 PF01048.20 KFQ96671.1 - 3.3e-19 69.1 0.1 4.5e-19 68.6 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Arm PF00514.23 KFQ96673.1 - 8e-45 149.6 10.5 5.7e-10 38.9 0.0 9.1 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KFQ96673.1 - 2.8e-06 27.6 0.3 0.042 14.2 0.0 3.0 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.22 KFQ96673.1 - 1.3e-05 25.1 3.3 0.98 9.9 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 KFQ96673.1 - 0.00098 19.6 1.4 1.4 9.5 0.0 4.5 4 0 0 4 4 4 1 HEAT-like repeat DUF2570 PF10828.8 KFQ96673.1 - 1.2 9.0 3.1 2.7 7.8 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) DAP PF15228.6 KFQ96674.1 - 2.9e-09 38.0 4.5 1e-08 36.2 4.5 1.7 1 1 0 1 1 1 1 Death-associated protein Ank_2 PF12796.7 KFQ96675.1 - 9.2e-59 196.0 2.0 2.7e-14 53.5 0.0 5.0 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ96675.1 - 1.6e-44 149.7 7.3 1e-07 32.3 0.0 7.7 3 2 6 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ96675.1 - 2e-36 119.9 0.3 0.0025 18.2 0.0 10.4 10 0 0 10 10 10 7 Ankyrin repeat Ank PF00023.30 KFQ96675.1 - 3.4e-34 115.8 4.0 0.00097 19.5 0.0 10.0 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 KFQ96675.1 - 7e-33 112.3 3.1 1.9e-09 37.6 0.0 7.9 2 2 5 8 8 8 6 Ankyrin repeats (many copies) TPR_2 PF07719.17 KFQ96675.1 - 3.2e-07 30.0 7.9 0.41 10.9 0.3 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFQ96675.1 - 2.6e-05 24.3 1.8 0.00072 19.7 0.8 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ96675.1 - 6.8e-05 23.4 3.0 0.001 19.6 0.0 2.8 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ96675.1 - 0.00021 20.9 4.5 1.5 8.6 0.1 3.5 3 0 0 3 3 3 3 TPR repeat TPR_8 PF13181.6 KFQ96675.1 - 0.00021 21.2 3.9 0.037 14.2 0.0 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat AAA_16 PF13191.6 KFQ96675.1 - 0.0018 18.7 0.3 0.016 15.6 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain TPR_19 PF14559.6 KFQ96675.1 - 0.002 18.6 3.3 0.77 10.3 0.3 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ96675.1 - 0.0032 17.2 7.4 4.1 7.4 1.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ96675.1 - 0.0045 17.7 2.8 0.019 15.8 2.8 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ96675.1 - 0.041 14.2 0.2 0.041 14.2 0.2 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ96675.1 - 0.098 12.7 0.2 6.5 7.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ96675.1 - 0.11 12.9 1.8 3 8.4 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat RP-C_C PF11800.8 KFQ96675.1 - 1.4 9.0 6.1 5.2 7.1 6.1 2.0 1 0 0 1 1 1 0 Replication protein C C-terminal region WD40 PF00400.32 KFQ96676.1 - 1.4e-43 146.0 15.5 6.8e-08 33.1 0.5 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat U-box PF04564.15 KFQ96676.1 - 7.9e-25 86.8 0.1 1.5e-24 85.9 0.1 1.5 1 0 0 1 1 1 1 U-box domain SAM_2 PF07647.17 KFQ96676.1 - 3.4e-13 49.5 0.3 5.9e-13 48.7 0.3 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) ANAPC4_WD40 PF12894.7 KFQ96676.1 - 2.1e-12 47.2 0.0 0.016 15.5 0.0 5.0 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain SAM_1 PF00536.30 KFQ96676.1 - 2e-11 44.1 0.2 4e-11 43.2 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) eIF2A PF08662.11 KFQ96676.1 - 1.5e-06 28.2 0.0 0.068 13.0 0.0 3.4 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFQ96676.1 - 3.3e-06 26.3 4.2 0.068 12.1 0.4 4.7 1 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KFQ96676.1 - 1e-05 24.1 0.0 0.14 10.5 0.0 2.6 2 1 1 3 3 3 3 WD repeat-containing and planar cell polarity effector protein Fritz SAM_PNT PF02198.16 KFQ96676.1 - 5.7e-05 23.0 0.1 0.00028 20.8 0.1 2.0 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain zf-NOSIP PF15906.5 KFQ96676.1 - 0.00013 22.0 0.9 0.00074 19.6 0.0 2.6 3 0 0 3 3 2 1 Zinc-finger of nitric oxide synthase-interacting protein PALB2_WD40 PF16756.5 KFQ96676.1 - 0.00016 20.8 0.6 0.012 14.6 0.0 2.7 2 1 1 3 3 3 2 Partner and localizer of BRCA2 WD40 domain SAM_3 PF18016.1 KFQ96676.1 - 0.0016 18.2 0.3 0.005 16.6 0.3 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) ELYS-bb PF16687.5 KFQ96676.1 - 0.0017 17.1 0.0 0.0027 16.4 0.0 1.3 1 0 0 1 1 1 1 beta-propeller of ELYS nucleoporin zf-Nse PF11789.8 KFQ96676.1 - 0.0094 15.8 0.1 0.034 14.0 0.0 2.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit DUF2415 PF10313.9 KFQ96676.1 - 0.23 11.4 3.2 9.8 6.2 0.0 4.0 4 0 0 4 4 4 0 Uncharacterised protein domain (DUF2415) Bromodomain PF00439.25 KFQ96677.1 - 4.9e-22 77.8 0.0 1.4e-21 76.3 0.0 1.8 1 0 0 1 1 1 1 Bromodomain MBD PF01429.19 KFQ96677.1 - 8e-14 51.1 0.1 2.5e-13 49.5 0.1 1.9 1 0 0 1 1 1 1 Methyl-CpG binding domain WSD PF15613.6 KFQ96677.1 - 7.7e-13 48.8 0.3 1.9e-07 31.4 0.1 5.7 6 0 0 6 6 6 2 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD PF00628.29 KFQ96677.1 - 1.2e-11 44.3 9.1 3.3e-11 42.9 9.1 1.8 1 0 0 1 1 1 1 PHD-finger DDT PF02791.17 KFQ96677.1 - 1.3e-08 35.0 0.3 2.9e-08 33.9 0.3 1.7 1 0 0 1 1 1 1 DDT domain Nop14 PF04147.12 KFQ96677.1 - 1.3e-06 27.0 11.2 1.3e-06 27.0 11.2 5.9 5 2 0 5 5 5 2 Nop14-like family BUD22 PF09073.10 KFQ96677.1 - 0.00063 19.2 41.2 0.0016 17.9 13.2 5.8 6 0 0 6 6 6 3 BUD22 RINGv PF12906.7 KFQ96678.1 - 2.5e-15 56.3 8.0 5.1e-15 55.3 8.0 1.6 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 KFQ96678.1 - 0.0003 20.9 4.2 0.0003 20.9 4.2 1.7 2 0 0 2 2 2 1 FANCL C-terminal domain zf-RING_2 PF13639.6 KFQ96678.1 - 0.0015 18.8 5.3 0.0031 17.8 5.3 1.5 1 0 0 1 1 1 1 Ring finger domain DUF1139 PF06599.11 KFQ96678.1 - 0.14 11.5 0.1 6.5 6.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1139) RIIa PF02197.17 KFQ96680.1 - 0.088 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit TMEM213 PF15192.6 KFQ96682.1 - 9e-32 108.9 1.5 9.5e-32 108.8 1.5 1.0 1 0 0 1 1 1 1 TMEM213 family V_ATPase_I PF01496.19 KFQ96683.1 - 0 1110.0 6.4 0 1109.8 6.4 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CSN7a_helixI PF18392.1 KFQ96683.1 - 5 7.1 6.0 67 3.5 0.1 3.7 4 0 0 4 4 4 0 COP9 signalosome complex subunit 7a helix I domain MFS_1 PF07690.16 KFQ96684.1 - 1.2e-29 103.4 45.6 4.2e-22 78.6 23.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFQ96684.1 - 4.5e-23 81.8 34.0 1.1e-18 67.3 10.2 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Bromodomain PF00439.25 KFQ96685.1 - 9.9e-23 80.0 0.1 2.5e-22 78.7 0.1 1.8 1 0 0 1 1 1 1 Bromodomain zf-B_box PF00643.24 KFQ96685.1 - 3.2e-11 43.2 24.0 1.9e-09 37.5 7.7 4.7 5 0 0 5 5 5 2 B-box zinc finger PHD PF00628.29 KFQ96685.1 - 3.2e-08 33.3 10.1 3.2e-08 33.3 10.1 4.6 4 1 0 4 4 4 1 PHD-finger zf-Sec23_Sec24 PF04810.15 KFQ96685.1 - 9.6 6.4 8.5 4 7.6 2.3 3.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Aldo_ket_red PF00248.21 KFQ96686.1 - 1e-46 159.5 0.0 1.3e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PARP PF00644.20 KFQ96687.1 - 2.9e-11 43.3 0.3 4.4e-08 32.9 0.2 2.8 2 1 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain HJURP_C PF12347.8 KFQ96687.1 - 0.021 14.8 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat PARP PF00644.20 KFQ96688.1 - 2e-41 141.8 1.6 2.3e-40 138.3 1.6 1.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain HJURP_C PF12347.8 KFQ96688.1 - 0.017 15.1 0.0 0.038 14.0 0.0 1.6 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat AA_permease_2 PF13520.6 KFQ96689.1 - 1e-51 176.2 36.8 1.2e-51 176.0 36.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFQ96689.1 - 3.7e-25 88.5 27.1 3.7e-25 88.5 27.1 2.0 2 0 0 2 2 2 1 Amino acid permease JHD PF17811.1 KFQ96690.1 - 1.5e-43 147.5 0.1 4.8e-43 145.9 0.1 1.9 1 0 0 1 1 1 1 Jumonji helical domain JmjC PF02373.22 KFQ96690.1 - 2.4e-10 40.8 5.4 5.6e-10 39.7 2.1 2.9 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KFQ96690.1 - 2.5e-08 34.0 0.3 2.5e-08 34.0 0.3 2.8 2 2 0 2 2 2 1 Cupin-like domain Ras PF00071.22 KFQ96691.1 - 2.9e-56 189.6 0.6 3.3e-56 189.4 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ96691.1 - 4.4e-36 123.7 0.4 6.8e-36 123.1 0.4 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ96691.1 - 2.5e-15 56.4 0.2 3.3e-15 56.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFQ96691.1 - 8e-06 25.5 0.6 4.1e-05 23.2 0.6 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFQ96691.1 - 3.7e-05 23.8 0.1 5.7e-05 23.2 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFQ96691.1 - 0.00013 21.4 0.2 0.00023 20.6 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFQ96691.1 - 0.00027 20.4 0.1 0.00065 19.2 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KFQ96691.1 - 0.00058 19.4 0.6 0.058 12.9 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B TniB PF05621.11 KFQ96691.1 - 0.002 17.5 0.1 0.0034 16.8 0.1 1.3 1 0 0 1 1 1 1 Bacterial TniB protein PduV-EutP PF10662.9 KFQ96691.1 - 0.0059 16.4 0.5 0.12 12.1 0.1 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 KFQ96691.1 - 0.034 13.9 0.0 0.048 13.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 KFQ96691.1 - 0.066 12.5 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Septin MKRN1_C PF15815.5 KFQ96692.1 - 3.1e-33 114.0 3.9 8.5e-33 112.6 3.9 1.7 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase makorin-1, C-terminal zf-CCCH_4 PF18044.1 KFQ96692.1 - 6.5e-29 99.2 42.4 3.4e-08 33.1 5.4 4.6 4 0 0 4 4 4 4 CCCH-type zinc finger Torus PF16131.5 KFQ96692.1 - 7.9e-18 65.1 18.7 3.8e-06 27.5 1.4 4.4 3 1 1 4 4 4 4 Torus domain zf-CCCH PF00642.24 KFQ96692.1 - 1.6e-15 56.6 38.6 1.5e-05 24.8 0.1 4.4 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFQ96692.1 - 9.1e-15 54.2 44.8 2.8e-06 27.2 5.3 5.0 4 1 0 4 4 4 3 Zinc finger domain zf-C3HC4 PF00097.25 KFQ96692.1 - 6.7e-07 29.1 7.1 6.7e-07 29.1 7.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFQ96692.1 - 8.7e-06 25.7 3.0 2.6e-05 24.2 3.0 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-CCCH_3 PF15663.5 KFQ96692.1 - 1.5e-05 25.2 6.1 1.5e-05 25.2 6.1 3.2 3 1 0 3 3 3 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KFQ96692.1 - 3.1e-05 24.3 34.1 0.09 13.3 3.9 4.9 4 1 0 4 4 4 4 RNA-binding, Nab2-type zinc finger zf-RING_5 PF14634.6 KFQ96692.1 - 3.6e-05 23.6 6.1 3.6e-05 23.6 6.1 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFQ96692.1 - 6e-05 23.3 6.2 6e-05 23.3 6.2 3.5 3 2 1 4 4 3 1 Ring finger domain zf-rbx1 PF12678.7 KFQ96692.1 - 0.00099 19.4 5.0 0.00099 19.4 5.0 3.3 3 0 0 3 3 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFQ96692.1 - 0.0011 18.9 3.7 0.0011 18.9 3.7 3.2 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KFQ96692.1 - 0.0036 17.4 4.0 0.0036 17.4 4.0 2.5 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KFQ96692.1 - 0.014 15.1 2.4 0.055 13.2 2.4 2.1 1 0 0 1 1 1 0 RING-like zinc finger DUF4929 PF16283.5 KFQ96692.1 - 0.21 10.6 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4929) zf-C3HC4_2 PF13923.6 KFQ96692.1 - 0.65 9.9 15.9 0.57 10.1 10.2 3.7 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Indigoidine_A PF04227.12 KFQ96693.1 - 1.1e-131 438.6 2.2 1.9e-131 437.7 2.1 1.5 2 0 0 2 2 2 1 Indigoidine synthase A like protein PfkB PF00294.24 KFQ96693.1 - 1e-19 71.0 0.0 2.3e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 pfkB family carbohydrate kinase TPP_enzyme_N PF02776.18 KFQ96693.1 - 0.12 12.0 0.4 1.5 8.4 0.0 2.9 3 1 0 3 3 3 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DENN PF02141.21 KFQ96694.1 - 6.2e-57 192.6 1.5 1.3e-56 191.5 1.5 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KFQ96694.1 - 4.7e-16 59.3 0.2 1e-15 58.2 0.2 1.6 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KFQ96694.1 - 8.9e-12 44.8 0.7 2.7e-11 43.3 0.7 1.8 1 0 0 1 1 1 1 dDENN domain SPA PF08616.10 KFQ96694.1 - 0.2 11.6 0.1 0.42 10.6 0.1 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis NADH_B2 PF14813.6 KFQ96695.1 - 4.3e-36 122.5 1.6 4.8e-36 122.4 1.6 1.0 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 Pkinase_Tyr PF07714.17 KFQ96697.1 - 1.2e-54 185.3 0.0 1.9e-54 184.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ96697.1 - 6.2e-47 160.2 0.0 9.8e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RBD PF02196.15 KFQ96697.1 - 1.6e-26 92.2 0.0 3.6e-26 91.0 0.0 1.7 1 0 0 1 1 1 1 Raf-like Ras-binding domain C1_1 PF00130.22 KFQ96697.1 - 3.3e-12 46.1 7.1 6.5e-12 45.1 7.1 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.11 KFQ96697.1 - 7.7e-05 22.9 2.7 0.00021 21.5 2.7 1.8 1 0 0 1 1 1 1 RING-like domain Kinase-like PF14531.6 KFQ96697.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like C1_2 PF03107.16 KFQ96697.1 - 0.0028 17.9 3.6 0.0071 16.6 3.6 1.7 1 0 0 1 1 1 1 C1 domain MRP-S33 PF08293.11 KFQ96698.1 - 1e-25 89.8 3.7 1.3e-25 89.5 3.7 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Claudin_2 PF13903.6 KFQ96699.1 - 1.6e-10 41.0 5.4 2e-10 40.7 5.4 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFQ96699.1 - 0.00016 21.6 4.5 0.00025 21.0 4.5 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DAGK_cat PF00781.24 KFQ96700.1 - 1.1e-24 86.5 0.1 1.6e-24 85.9 0.1 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 KFQ96700.1 - 0.0012 18.2 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Tim54 PF11711.8 KFQ96700.1 - 0.0039 16.0 0.1 0.012 14.4 0.0 1.8 2 0 0 2 2 2 1 Inner membrane protein import complex subunit Tim54 GATase PF00117.28 KFQ96700.1 - 0.051 13.3 0.0 0.083 12.7 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I DUF2347 PF09804.9 KFQ96701.1 - 1e-72 245.1 0.0 1.4e-72 244.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 KFQ96701.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KFQ96701.1 - 2.9e-09 36.1 2.1 0.00038 19.3 0.2 3.2 2 1 0 2 2 2 2 Transport protein Avl9 Baculo_LEF-11 PF06385.12 KFQ96701.1 - 0.067 13.7 0.8 0.13 12.8 0.8 1.4 1 0 0 1 1 1 0 Baculovirus LEF-11 protein SSB PF00436.25 KFQ96702.1 - 4.5e-31 107.0 0.3 5.4e-31 106.7 0.3 1.1 1 0 0 1 1 1 1 Single-strand binding protein family bZIP_1 PF00170.21 KFQ96703.1 - 6.2e-15 55.1 16.0 1.3e-14 54.0 16.0 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFQ96703.1 - 4.9e-09 36.1 10.8 4.9e-09 36.1 10.8 2.3 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFQ96703.1 - 1.6e-06 28.6 10.7 3e-06 27.6 10.7 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor ZapB PF06005.12 KFQ96703.1 - 0.007 16.8 3.2 0.022 15.2 3.2 1.8 1 0 0 1 1 1 1 Cell division protein ZapB Fmp27_WPPW PF10359.9 KFQ96703.1 - 0.0081 15.1 0.4 0.012 14.5 0.4 1.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Goodbye PF17109.5 KFQ96703.1 - 0.017 15.6 0.5 0.038 14.4 0.5 1.6 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain HAUS6_N PF14661.6 KFQ96703.1 - 0.023 14.3 2.2 0.088 12.4 2.6 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus TPR_MLP1_2 PF07926.12 KFQ96703.1 - 0.049 13.7 10.5 0.08 13.0 10.5 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.11 KFQ96703.1 - 0.052 13.9 2.0 0.14 12.6 2.0 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Jnk-SapK_ap_N PF09744.9 KFQ96703.1 - 0.053 13.7 7.5 0.096 12.9 7.5 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 HAUS-augmin3 PF14932.6 KFQ96703.1 - 0.059 12.9 5.4 0.12 11.9 5.4 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 JMY PF15871.5 KFQ96703.1 - 0.076 12.3 5.7 0.12 11.7 5.7 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein APG6_N PF17675.1 KFQ96703.1 - 0.088 13.3 6.5 0.18 12.3 6.5 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region ADIP PF11559.8 KFQ96703.1 - 0.22 11.6 11.0 0.38 10.8 11.0 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 KFQ96703.1 - 0.23 11.3 7.0 0.38 10.6 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FOXP-CC PF16159.5 KFQ96703.1 - 0.24 12.0 1.7 0.59 10.8 1.7 1.7 1 0 0 1 1 1 0 FOXP coiled-coil domain TBCA PF02970.16 KFQ96703.1 - 0.27 11.6 7.4 0.57 10.6 7.4 1.5 1 0 0 1 1 1 0 Tubulin binding cofactor A DUF4404 PF14357.6 KFQ96703.1 - 0.63 10.7 5.0 1.2 9.8 2.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF1664 PF07889.12 KFQ96703.1 - 1 9.4 4.5 1.6 8.8 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) PTN_MK_C PF01091.18 KFQ96704.1 - 9.7e-28 96.4 9.4 9.7e-28 96.4 9.4 3.0 2 1 1 3 3 3 1 PTN/MK heparin-binding protein family, C-terminal domain PTN_MK_N PF05196.13 KFQ96704.1 - 2.2e-26 91.8 16.6 2.2e-26 91.8 16.6 2.7 3 1 0 3 3 3 1 PTN/MK heparin-binding protein family, N-terminal domain UPF0239 PF06783.11 KFQ96704.1 - 3.6 7.8 8.4 4.6 7.5 0.1 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0239) 7tm_1 PF00001.21 KFQ96706.1 - 8.9e-74 248.1 7.1 1.3e-73 247.6 7.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFQ96706.1 - 1.7e-06 27.9 12.1 1.7e-06 27.9 12.1 2.3 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFQ96706.1 - 4.9e-06 26.5 5.5 4.9e-06 26.5 5.5 2.6 2 1 0 3 3 3 1 Olfactory receptor MRP-S24 PF14955.6 KFQ96710.1 - 4.8e-38 130.2 0.0 5.2e-38 130.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S24 RVT_1 PF00078.27 KFQ96712.1 - 0.087 12.3 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Laminin_G_2 PF02210.24 KFQ96714.1 - 4.2e-21 75.8 0.2 6.3e-16 59.1 0.1 2.2 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 KFQ96714.1 - 2.6e-15 56.8 0.0 5.6e-11 42.8 0.0 2.1 2 0 0 2 2 2 2 Laminin G domain DUF4154 PF13689.6 KFQ96714.1 - 0.063 13.5 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 YfiR/HmsC-like DUF3791 PF12668.7 KFQ96714.1 - 0.13 12.3 0.1 0.71 10.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) F5_F8_type_C PF00754.25 KFQ96716.1 - 1e-17 64.4 2.6 1.2e-17 64.3 2.6 1.0 1 0 0 1 1 1 1 F5/8 type C domain SecE PF00584.20 KFQ96718.1 - 6.4e-17 61.2 0.1 8.1e-17 60.9 0.1 1.2 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Pkinase_Tyr PF07714.17 KFQ96719.1 - 5.8e-89 297.8 0.0 8.5e-89 297.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.24 KFQ96719.1 - 2.5e-60 201.5 2.3 5e-30 103.9 2.2 2.5 2 0 0 2 2 2 2 Receptor L domain GF_recep_IV PF14843.6 KFQ96719.1 - 5.3e-55 184.8 81.2 1.4e-47 160.8 25.4 4.0 2 1 1 4 4 4 2 Growth factor receptor domain IV Pkinase PF00069.25 KFQ96719.1 - 7.5e-40 137.0 0.0 1.1e-39 136.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.20 KFQ96719.1 - 1.6e-35 122.2 88.5 3.9e-30 104.7 42.3 4.2 2 1 2 4 4 4 3 Furin-like cysteine rich region APH PF01636.23 KFQ96719.1 - 0.022 14.7 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFQ96719.1 - 0.064 12.2 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KFQ96719.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Kinase-like DUF4462 PF14692.6 KFQ96720.1 - 0.095 12.2 0.9 0.61 9.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) LANC_like PF05147.13 KFQ96721.1 - 4.8e-91 304.9 0.3 5.5e-91 304.8 0.3 1.0 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein C5-epim_C PF06662.13 KFQ96721.1 - 0.0055 16.2 0.1 0.71 9.3 0.0 2.9 3 0 0 3 3 3 1 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_88 PF07470.13 KFQ96721.1 - 0.042 12.9 1.4 0.58 9.2 0.2 2.6 1 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 KFQ96721.1 - 0.097 11.1 0.3 1.6 7.1 0.1 2.3 2 1 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Neil1-DNA_bind PF09292.10 KFQ96721.1 - 0.15 12.1 0.0 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Endonuclease VIII-like 1, DNA bind TMEM52 PF14979.6 KFQ96722.1 - 0.034 14.1 9.3 0.12 12.3 1.8 2.1 2 0 0 2 2 2 0 Transmembrane 52 WBP-1 PF11669.8 KFQ96722.1 - 0.083 13.5 18.0 0.41 11.3 17.9 2.1 1 1 0 1 1 1 0 WW domain-binding protein 1 Biliv-reduc_cat PF09166.10 KFQ96723.1 - 4.2e-58 194.6 0.0 6.9e-58 193.9 0.0 1.4 1 0 0 1 1 1 1 Biliverdin reductase, catalytic GFO_IDH_MocA PF01408.22 KFQ96723.1 - 1.7e-17 64.4 0.2 4.9e-17 62.9 0.2 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KFQ96723.1 - 0.13 12.9 0.1 0.27 11.9 0.1 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Pkinase PF00069.25 KFQ96724.1 - 6.3e-70 235.5 0.1 9.6e-70 235.0 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ96724.1 - 9.4e-32 110.3 0.1 1.3e-31 109.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ96724.1 - 4e-05 23.1 0.0 6.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFQ96724.1 - 0.00012 21.6 0.1 0.00019 20.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SPOUT_MTase_2 PF14419.6 KFQ96724.1 - 0.039 13.3 0.1 0.063 12.7 0.1 1.3 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP RIO1 PF01163.22 KFQ96724.1 - 0.045 13.4 0.3 0.084 12.5 0.3 1.5 1 1 0 1 1 1 0 RIO1 family APH PF01636.23 KFQ96724.1 - 0.058 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family SRA1 PF07304.11 KFQ96724.1 - 0.061 13.1 0.2 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) Pox_ser-thr_kin PF05445.11 KFQ96724.1 - 0.16 10.9 0.2 0.29 10.0 0.1 1.5 1 1 0 1 1 1 0 Poxvirus serine/threonine protein kinase HECT PF00632.25 KFQ96725.1 - 5.4e-106 354.5 0.0 7.7e-106 354.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECW_N PF16562.5 KFQ96725.1 - 3.7e-59 197.8 0.6 7.8e-59 196.7 0.6 1.6 1 0 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 HECW1_helix PF18436.1 KFQ96725.1 - 7.5e-38 128.5 4.4 8.2e-35 118.7 2.7 2.7 2 0 0 2 2 2 2 Helical box domain of E3 ubiquitin-protein ligase HECW1 WW PF00397.26 KFQ96725.1 - 2.3e-17 62.8 0.5 8.8e-10 38.5 0.5 2.6 2 0 0 2 2 2 2 WW domain C2 PF00168.30 KFQ96725.1 - 7.6e-11 42.2 0.0 3e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 C2 domain Keratin_B2_2 PF13885.6 KFQ96725.1 - 2.1 8.4 22.3 5.2 7.1 22.3 1.6 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein RFXA_RFXANK_bdg PF15289.6 KFQ96725.1 - 2.8 8.3 7.8 1.4 9.3 0.1 3.2 3 0 0 3 3 3 0 Regulatory factor X-associated C-terminal binding domain Ribosomal_L32p PF01783.23 KFQ96726.1 - 1.7e-08 34.6 6.7 2.7e-08 33.9 6.7 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family RecR PF02132.15 KFQ96726.1 - 0.00034 20.1 0.8 0.0006 19.3 0.8 1.4 1 0 0 1 1 1 1 RecR protein DZR PF12773.7 KFQ96726.1 - 0.068 13.2 1.8 0.24 11.5 1.3 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KFQ96726.1 - 0.08 12.4 2.0 0.17 11.3 2.0 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Proteasome PF00227.26 KFQ96727.1 - 1.9e-60 203.6 0.0 2.5e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFQ96727.1 - 6.3e-06 25.8 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PBP_dimer PF03717.15 KFQ96727.1 - 0.049 14.0 0.0 6.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Penicillin-binding Protein dimerisation domain DUF5614 PF18474.1 KFQ96728.1 - 3.7e-125 415.5 1.0 5.7e-125 414.9 1.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5614) DUF1308 PF07000.11 KFQ96728.1 - 1.7e-70 236.3 0.1 8.4e-70 234.0 0.0 2.1 2 1 1 3 3 3 1 Protein of unknown function (DUF1308) ACT_4 PF13291.6 KFQ96728.1 - 0.26 11.9 1.1 35 5.1 0.1 2.9 2 1 1 3 3 3 0 ACT domain zf-C2H2 PF00096.26 KFQ96730.1 - 2.4e-20 71.8 30.5 0.00032 21.0 0.5 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ96730.1 - 1.1e-11 44.6 31.0 1.6e-06 28.2 1.4 5.3 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ96730.1 - 3.6e-07 30.5 29.0 0.0049 17.6 0.3 6.0 5 0 0 5 5 5 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFQ96730.1 - 1.7e-06 28.6 20.5 0.045 14.4 6.7 5.1 1 1 2 4 4 4 2 FOXP coiled-coil domain zf_ZIC PF18366.1 KFQ96730.1 - 0.23 11.6 9.4 1.7 8.8 0.6 3.8 1 1 2 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_aberr PF17017.5 KFQ96730.1 - 0.95 9.6 15.7 9.3 6.4 2.4 3.5 2 1 1 3 3 3 0 Aberrant zinc-finger PcF PF09461.10 KFQ96730.1 - 3.2 8.2 5.4 38 4.7 0.3 3.6 2 1 1 3 3 3 0 Phytotoxin PcF protein TGF_beta PF00019.20 KFQ96731.1 - 7.3e-31 107.2 1.2 1.6e-30 106.2 1.2 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFQ96731.1 - 1.4e-08 34.8 1.3 1.1e-07 31.9 1.3 2.2 1 1 0 1 1 1 1 TGF-beta propeptide CoA_transf_3 PF02515.17 KFQ96732.1 - 1.2e-63 215.5 0.0 1.4e-63 215.2 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Pkinase PF00069.25 KFQ96733.1 - 2.1e-74 250.2 0.0 3.2e-74 249.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ96733.1 - 2.2e-35 122.2 0.0 3.5e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFQ96733.1 - 7.7e-08 31.7 0.3 7.7e-08 31.7 0.3 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 KFQ96733.1 - 1.4e-05 24.6 0.0 9.6e-05 21.8 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFQ96733.1 - 0.016 14.5 0.2 0.031 13.7 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFQ96733.1 - 0.25 10.1 0.0 0.25 10.1 0.0 2.6 3 0 0 3 3 3 0 Fungal protein kinase Ras PF00071.22 KFQ96734.1 - 7.8e-56 188.1 0.3 9.3e-56 187.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ96734.1 - 1.7e-19 70.2 0.0 3.1e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ96734.1 - 2e-10 40.4 0.0 2.6e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFQ96734.1 - 7.1e-09 35.8 0.1 5.3e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFQ96734.1 - 6.9e-05 22.5 0.2 0.0002 20.9 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFQ96734.1 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KFQ96734.1 - 0.01 15.2 0.1 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_25 PF13481.6 KFQ96734.1 - 0.012 15.2 0.2 0.055 13.0 0.1 1.9 1 1 1 2 2 2 0 AAA domain ThiF PF00899.21 KFQ96734.1 - 0.11 11.8 2.0 0.18 11.1 0.1 2.1 2 0 0 2 2 2 0 ThiF family MeaB PF03308.16 KFQ96734.1 - 0.15 11.0 0.4 2 7.3 0.3 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Med1 PF10744.9 KFQ96735.1 - 2e-61 208.3 0.1 2.5e-61 208.0 0.1 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Yae1_N PF09811.9 KFQ96736.1 - 3.5e-13 49.0 1.8 5.5e-13 48.4 1.8 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal DUF2385 PF09539.10 KFQ96736.1 - 0.021 15.3 0.1 0.13 12.8 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2385) ACT_7 PF13840.6 KFQ96737.1 - 9.7e-35 118.2 0.0 2.1e-19 69.1 0.0 2.3 2 0 0 2 2 2 2 ACT domain Castor1_N PF18700.1 KFQ96737.1 - 8.8e-18 63.9 2.1 6.6e-17 61.1 0.4 2.7 3 0 0 3 3 3 1 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain Auts2 PF15336.6 KFQ96738.1 - 1.7e-104 348.7 15.8 1.7e-104 348.7 15.8 6.2 3 2 2 6 6 6 1 Autism susceptibility gene 2 protein Glycos_transf_2 PF00535.26 KFQ96739.1 - 1.4e-28 99.8 0.0 2.2e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFQ96739.1 - 4.8e-18 65.6 0.1 7.6e-18 65.0 0.1 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 KFQ96739.1 - 2e-05 24.6 0.0 0.001 19.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.6 KFQ96739.1 - 0.016 15.9 0.1 0.065 14.0 0.0 1.9 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Glyco_transf_7C PF02709.14 KFQ96739.1 - 0.14 11.8 0.0 0.5 10.0 0.0 1.9 2 0 0 2 2 2 0 N-terminal domain of galactosyltransferase EF-hand_1 PF00036.32 KFQ96740.1 - 8.1e-17 59.5 8.8 1.1e-08 34.0 0.1 4.0 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 KFQ96740.1 - 4.2e-15 55.9 1.7 1.2e-13 51.3 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KFQ96740.1 - 9.2e-15 53.2 2.8 2.4e-08 33.3 0.0 3.7 3 1 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KFQ96740.1 - 6.9e-13 48.2 8.8 1.4e-09 37.7 0.4 4.2 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 KFQ96740.1 - 2.2e-12 45.9 10.4 8.7e-06 25.0 0.1 4.2 3 1 1 4 4 4 2 EF hand EF-hand_9 PF14658.6 KFQ96740.1 - 0.00098 19.4 0.0 0.0034 17.7 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 KFQ96740.1 - 0.0084 16.0 0.2 0.023 14.7 0.2 1.7 1 1 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFQ96740.1 - 0.012 16.0 0.2 0.043 14.1 0.0 2.0 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.10 KFQ96740.1 - 0.12 12.5 0.2 0.48 10.6 0.0 2.2 2 1 0 2 2 2 0 Ca2+ insensitive EF hand Radical_SAM PF04055.21 KFQ96741.1 - 8e-29 101.2 0.0 2.2e-28 99.8 0.0 1.8 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 KFQ96741.1 - 1.6e-28 98.9 0.1 3.9e-28 97.6 0.1 1.7 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.25 KFQ96741.1 - 1.8e-23 83.3 0.1 3.5e-23 82.4 0.1 1.5 1 0 0 1 1 1 1 Flavodoxin DUF4769 PF15992.5 KFQ96741.1 - 0.082 12.7 1.4 0.17 11.7 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) Adaptin_binding PF10199.9 KFQ96741.1 - 0.15 12.7 3.8 0.13 12.9 2.1 1.7 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 SBDS_C PF09377.10 KFQ96742.1 - 6.1e-39 132.6 0.9 7.3e-39 132.4 0.9 1.1 1 0 0 1 1 1 1 SBDS protein C-terminal domain Septin PF00735.18 KFQ96743.1 - 2.6e-132 440.3 0.3 3e-132 440.1 0.3 1.0 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 KFQ96743.1 - 5.5e-08 32.9 0.1 2.4e-05 24.3 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFQ96743.1 - 5.7e-08 32.8 0.0 1.1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFQ96743.1 - 3.9e-06 26.5 0.1 0.0047 16.5 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KFQ96743.1 - 0.00026 20.4 0.0 0.00079 18.8 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 KFQ96743.1 - 0.0029 17.7 1.2 0.52 10.3 0.0 2.6 1 1 1 2 2 2 1 Dynamin family Ras PF00071.22 KFQ96743.1 - 0.006 16.2 0.1 0.016 14.8 0.1 1.7 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ96743.1 - 0.012 15.8 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KFQ96743.1 - 0.015 15.7 0.0 0.027 14.8 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KFQ96743.1 - 0.016 15.7 0.0 0.039 14.5 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KFQ96743.1 - 0.032 14.5 0.0 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KFQ96743.1 - 0.04 13.7 0.1 0.091 12.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 KFQ96743.1 - 0.045 12.9 0.3 3.1 6.9 0.1 2.4 1 1 1 2 2 2 0 G-protein alpha subunit Pkinase_Tyr PF07714.17 KFQ96744.1 - 2.4e-52 177.8 0.0 3.9e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ96744.1 - 1.6e-48 165.4 0.0 2.6e-48 164.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LIM PF00412.22 KFQ96744.1 - 7.6e-31 106.1 24.2 1.9e-16 60.0 10.0 2.5 2 0 0 2 2 2 2 LIM domain PDZ PF00595.24 KFQ96744.1 - 1.9e-12 47.4 0.0 4e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Kdo PF06293.14 KFQ96744.1 - 6.1e-08 32.3 0.2 1.2e-07 31.3 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PDZ_6 PF17820.1 KFQ96744.1 - 0.00018 21.3 0.1 0.0017 18.1 0.0 2.3 2 0 0 2 2 2 1 PDZ domain APH PF01636.23 KFQ96744.1 - 0.0018 18.2 0.1 0.0047 16.9 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFQ96744.1 - 0.017 14.8 0.1 0.03 13.9 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KFQ96744.1 - 0.021 13.8 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KFQ96744.1 - 0.042 12.6 0.0 0.064 12.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase PDZ_4 PF17816.1 KFQ96744.1 - 0.049 14.0 0.1 1.2 9.6 0.0 2.4 2 0 0 2 2 2 0 PDZ domain PknG_TPR PF16918.5 KFQ96744.1 - 0.083 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat PDZ_2 PF13180.6 KFQ96744.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Kinase-like PF14531.6 KFQ96744.1 - 0.18 11.1 0.1 19 4.5 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Abhydrolase_1 PF00561.20 KFQ96746.1 - 4.3e-16 59.3 0.1 2e-13 50.6 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFQ96746.1 - 5.2e-15 56.6 0.0 6.2e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFQ96746.1 - 1.4e-09 37.6 0.1 2.6e-09 36.7 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KFQ96746.1 - 1.7e-05 24.7 0.1 2.5e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.20 KFQ96746.1 - 0.00038 20.2 0.0 0.00052 19.7 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 KFQ96746.1 - 0.00049 20.3 0.0 0.0006 20.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Chlorophyllase2 PF12740.7 KFQ96746.1 - 0.0042 16.0 0.0 0.0062 15.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF2048 PF09752.9 KFQ96746.1 - 0.019 14.1 0.0 0.13 11.3 0.0 1.9 1 1 0 1 1 1 0 Abhydrolase domain containing 18 Lipase_3 PF01764.25 KFQ96746.1 - 0.02 14.8 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase PF07224.11 KFQ96746.1 - 0.035 13.1 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Ndr PF03096.14 KFQ96746.1 - 0.063 12.0 0.0 0.14 10.8 0.0 1.5 2 0 0 2 2 2 0 Ndr family Ser_hydrolase PF06821.13 KFQ96746.1 - 0.1 12.5 0.0 13 5.6 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase DUF1057 PF06342.12 KFQ96746.1 - 0.19 10.7 0.1 0.3 10.1 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) PAF-AH_p_II PF03403.13 KFQ96746.1 - 0.22 10.0 0.0 0.31 9.5 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Peptidase_C14 PF00656.22 KFQ96747.1 - 3.6e-43 148.3 0.0 4.6e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain CARD PF00619.21 KFQ96747.1 - 5.3e-17 61.6 0.1 1.6e-16 60.1 0.1 1.8 2 0 0 2 2 2 1 Caspase recruitment domain Myotub-related PF06602.14 KFQ96748.1 - 1.1e-136 455.5 0.0 1.4e-136 455.1 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 KFQ96748.1 - 0.0032 17.1 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFQ96748.1 - 0.0077 16.1 0.0 0.021 14.6 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFQ96748.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family HSF_DNA-bind PF00447.17 KFQ96749.1 - 3.7e-14 53.1 0.0 7.1e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding ZNRF_3_ecto PF18212.1 KFQ96750.1 - 1.1e-49 166.7 0.0 1.8e-49 166.0 0.0 1.4 1 0 0 1 1 1 1 ZNRF-3 Ectodomain zf-RING_2 PF13639.6 KFQ96750.1 - 2.5e-12 46.9 8.9 2.5e-12 46.9 8.9 2.6 4 0 0 4 4 1 1 Ring finger domain zf-RING_11 PF17123.5 KFQ96750.1 - 4.6e-11 42.3 4.2 1.3e-10 40.8 4.2 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFQ96750.1 - 1.4e-09 37.6 7.5 1.4e-09 37.6 7.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ96750.1 - 1.8e-07 30.9 7.2 1.8e-07 30.9 7.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFQ96750.1 - 2.9e-06 27.5 10.7 2.9e-06 27.5 10.7 2.5 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFQ96750.1 - 8.6e-06 25.7 5.0 8.6e-06 25.7 5.0 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFQ96750.1 - 4.7e-05 23.2 6.3 0.00019 21.3 6.3 2.1 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFQ96750.1 - 0.00014 21.6 5.9 0.00043 20.1 5.9 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF3827 PF12877.7 KFQ96750.1 - 0.0085 14.5 0.3 0.013 14.0 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) zf-C3HC4_3 PF13920.6 KFQ96750.1 - 0.017 14.9 4.0 0.017 14.9 4.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KFQ96750.1 - 0.077 13.2 4.3 0.23 11.7 4.3 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain DUF5305 PF17231.2 KFQ96750.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) zf-ANAPC11 PF12861.7 KFQ96750.1 - 0.12 12.5 7.1 0.52 10.4 7.1 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 KFQ96750.1 - 3.7 7.5 12.3 1.2 9.0 6.6 2.5 2 0 0 2 2 2 0 PHD-finger RINGv PF12906.7 KFQ96750.1 - 4.1 7.6 8.3 13 6.0 8.3 1.9 1 0 0 1 1 1 0 RING-variant domain Spt4 PF06093.13 KFQ96752.1 - 1.3e-26 92.5 0.1 1.6e-26 92.2 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger An_peroxidase PF03098.15 KFQ96753.1 - 1e-182 608.5 0.0 1.2e-182 608.2 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase IL8 PF00048.20 KFQ96754.1 - 2.5e-24 85.2 0.5 2.7e-24 85.1 0.5 1.0 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like IL8 PF00048.20 KFQ96755.1 - 6.7e-23 80.6 0.7 8.8e-23 80.2 0.7 1.2 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like IL8 PF00048.20 KFQ96756.1 - 1.8e-23 82.4 0.5 2.6e-23 81.9 0.5 1.2 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like ANTH PF07651.16 KFQ96757.1 - 6.4e-73 245.1 8.3 1.2e-71 240.9 0.1 2.6 2 0 0 2 2 2 2 ANTH domain I_LWEQ PF01608.17 KFQ96757.1 - 1.1e-53 181.6 9.3 1.1e-53 181.6 9.3 4.0 2 1 2 4 4 4 1 I/LWEQ domain HIP1_clath_bdg PF16515.5 KFQ96757.1 - 2.6e-26 92.1 14.5 2.6e-26 92.1 14.5 6.1 4 2 1 5 5 5 1 Clathrin-binding domain of Huntingtin-interacting protein 1 ATG16 PF08614.11 KFQ96757.1 - 0.059 13.6 74.7 2.5 8.3 41.3 4.3 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KFQ96757.1 - 3.6 6.4 65.0 0.0086 15.0 26.5 3.7 2 1 1 3 3 3 0 Spc7 kinetochore protein POM121 PF15229.6 KFQ96758.1 - 2.1e-104 348.3 22.1 2.1e-104 348.3 22.1 3.5 4 0 0 4 4 4 1 POM121 family FKBP_C PF00254.28 KFQ96759.1 - 3.7e-14 52.8 0.0 8.6e-14 51.6 0.0 1.6 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 KFQ96759.1 - 7.2e-09 35.1 7.1 0.001 19.0 0.3 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ96759.1 - 5.1e-08 33.1 3.7 0.00018 21.7 2.3 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ96759.1 - 0.00075 19.5 2.2 0.0044 17.1 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ96759.1 - 0.00086 19.0 6.2 0.054 13.3 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ96759.1 - 0.0022 18.2 4.4 0.045 14.0 3.1 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KFQ96759.1 - 0.0024 17.7 2.9 0.0091 15.8 0.8 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ96759.1 - 0.0039 17.7 3.2 0.011 16.3 2.2 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ96759.1 - 0.0083 16.1 2.6 3.1 8.0 0.3 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ96759.1 - 0.01 16.5 3.3 0.34 11.6 0.8 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ96759.1 - 0.011 15.3 0.8 0.071 12.8 0.1 2.5 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.6 KFQ96759.1 - 0.1 13.5 3.4 1.6 9.7 1.1 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFQ96759.1 - 0.14 12.3 1.0 2.2 8.4 0.0 2.4 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 KFQ96759.1 - 0.22 12.0 1.1 6.9 7.3 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Frizzled PF01534.17 KFQ96760.1 - 5.2e-135 449.7 19.6 7e-135 449.2 19.6 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 KFQ96760.1 - 1.3e-28 99.8 1.4 2.7e-28 98.8 1.4 1.5 1 0 0 1 1 1 1 Fz domain DUF5083 PF16890.5 KFQ96760.1 - 0.18 11.6 0.7 0.39 10.4 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5083) Bromodomain PF00439.25 KFQ96761.1 - 2.1e-22 79.0 0.2 6.4e-22 77.4 0.2 1.9 1 0 0 1 1 1 1 Bromodomain WSD PF15613.6 KFQ96761.1 - 1.2e-21 77.0 0.0 1.2e-21 77.0 0.0 4.8 4 1 0 4 4 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WAC_Acf1_DNA_bd PF10537.9 KFQ96761.1 - 2.4e-19 69.7 0.9 2.4e-19 69.7 0.9 2.6 2 0 0 2 2 1 1 ATP-utilising chromatin assembly and remodelling N-terminal PHD PF00628.29 KFQ96761.1 - 2.5e-13 49.7 6.1 7.4e-13 48.2 6.1 1.9 1 0 0 1 1 1 1 PHD-finger WHIM1 PF15612.6 KFQ96761.1 - 9.2e-08 31.5 2.0 1.7e-07 30.6 0.1 2.7 3 0 0 3 3 3 1 WSTF, HB1, Itc1p, MBD9 motif 1 DDT PF02791.17 KFQ96761.1 - 0.00098 19.4 1.6 0.0014 18.9 0.3 2.0 2 0 0 2 2 2 1 DDT domain zf-HC5HC2H PF13771.6 KFQ96761.1 - 0.018 15.3 3.3 0.074 13.3 3.3 2.0 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-ANAPC11 PF12861.7 KFQ96761.1 - 0.029 14.4 1.9 0.075 13.1 1.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KFQ96761.1 - 0.034 14.5 5.9 0.088 13.2 5.9 1.8 1 0 0 1 1 1 0 Ring finger domain PHD_2 PF13831.6 KFQ96761.1 - 0.039 13.5 0.4 0.11 12.1 0.4 1.8 1 0 0 1 1 1 0 PHD-finger zf-rbx1 PF12678.7 KFQ96761.1 - 0.069 13.4 6.7 0.21 11.9 6.7 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain PHD_4 PF16866.5 KFQ96761.1 - 1.1 9.4 5.6 8.9 6.5 5.6 2.7 1 0 0 1 1 1 0 PHD-finger C1_2 PF03107.16 KFQ96761.1 - 1.4 9.3 7.9 0.77 10.1 4.5 2.4 2 0 0 2 2 2 0 C1 domain Prok-RING_1 PF14446.6 KFQ96761.1 - 2.9 7.9 12.7 0.03 14.3 1.5 3.1 4 0 0 4 4 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 KFQ96761.1 - 8.7 6.2 8.8 46 3.9 8.3 2.5 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain B9-C2 PF07162.11 KFQ96763.1 - 1.4e-52 178.3 0.1 2.3e-52 177.6 0.1 1.3 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein DUF4175 PF13779.6 KFQ96763.1 - 0.059 11.3 1.1 0.086 10.7 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Syntaxin PF00804.25 KFQ96764.1 - 7e-65 218.5 14.7 1.1e-64 217.8 14.7 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KFQ96764.1 - 4.9e-22 77.7 4.0 1.8e-21 75.9 1.9 2.5 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 KFQ96764.1 - 6.6e-12 45.7 6.6 6.6e-12 45.7 6.6 2.4 1 1 1 2 2 2 1 Syntaxin-like protein Prominin PF05478.11 KFQ96764.1 - 0.0011 17.0 12.9 0.051 11.5 13.1 2.1 1 1 0 1 1 1 1 Prominin Laminin_II PF06009.12 KFQ96764.1 - 0.0072 16.4 1.7 0.0072 16.4 1.7 2.4 2 1 0 2 2 2 1 Laminin Domain II GNVR PF13807.6 KFQ96764.1 - 0.0082 16.0 0.1 0.045 13.7 0.1 2.1 2 0 0 2 2 2 1 G-rich domain on putative tyrosine kinase Ferritin PF00210.24 KFQ96764.1 - 0.011 15.7 0.9 0.011 15.7 0.9 1.8 2 0 0 2 2 2 0 Ferritin-like domain DUF948 PF06103.11 KFQ96764.1 - 0.013 15.8 4.1 1.3 9.3 0.3 3.8 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Lzipper-MIP1 PF14389.6 KFQ96764.1 - 0.032 14.5 4.6 0.034 14.4 0.2 2.6 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 CorA PF01544.18 KFQ96764.1 - 0.037 13.3 7.4 0.16 11.3 0.9 2.5 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein WXG100 PF06013.12 KFQ96764.1 - 0.04 14.1 2.1 3.6 7.9 0.2 3.5 4 0 0 4 4 4 0 Proteins of 100 residues with WXG GlutR_dimer PF00745.20 KFQ96764.1 - 0.041 14.3 5.9 3 8.4 1.1 2.7 1 1 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain SIMPL PF04402.14 KFQ96764.1 - 0.046 14.2 4.4 0.13 12.7 4.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF541) Syntaxin-6_N PF09177.11 KFQ96764.1 - 0.13 12.8 12.4 0.055 14.0 4.0 3.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Sec34 PF04136.15 KFQ96764.1 - 0.19 11.6 10.2 3.4 7.6 3.8 3.2 2 1 1 3 3 3 0 Sec34-like family MCPsignal PF00015.21 KFQ96764.1 - 0.25 11.1 8.6 3.9 7.3 1.8 2.9 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain YtxH PF12732.7 KFQ96764.1 - 0.26 11.9 8.2 0.19 12.3 1.3 3.2 3 1 0 3 3 2 0 YtxH-like protein DUF2508 PF10704.9 KFQ96764.1 - 0.27 11.4 3.0 1.2 9.4 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) LOH1CR12 PF10158.9 KFQ96764.1 - 0.41 10.7 7.5 2.7 8.0 0.7 2.6 2 1 0 2 2 2 0 Tumour suppressor protein Nup54 PF13874.6 KFQ96764.1 - 0.53 10.4 9.6 16 5.6 6.3 2.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 PspA_IM30 PF04012.12 KFQ96764.1 - 0.57 9.7 10.9 0.074 12.6 4.9 2.2 2 1 1 3 3 3 0 PspA/IM30 family DUF16 PF01519.16 KFQ96764.1 - 0.7 10.4 12.3 0.33 11.4 0.5 3.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 HAUS6_N PF14661.6 KFQ96764.1 - 0.78 9.3 9.7 8.1 6.0 7.9 2.4 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus FapA PF03961.13 KFQ96764.1 - 0.89 8.1 15.0 0.091 11.3 7.4 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF848 PF05852.11 KFQ96764.1 - 1 9.5 12.4 0.3 11.2 4.6 2.7 2 2 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Lipoprotein_2 PF00921.17 KFQ96764.1 - 1 8.9 8.3 0.069 12.7 1.8 2.2 3 0 0 3 3 3 0 Borrelia lipoprotein Med9 PF07544.13 KFQ96764.1 - 1.1 9.4 8.7 0.72 10.0 2.4 3.3 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF1910 PF08928.10 KFQ96764.1 - 1.1 9.2 13.3 0.38 10.8 1.0 3.1 1 1 0 2 2 2 0 Domain of unknown function (DUF1910) Fez1 PF06818.15 KFQ96764.1 - 1.2 9.6 15.7 3.9 7.9 0.9 2.2 2 0 0 2 2 2 0 Fez1 DUF745 PF05335.13 KFQ96764.1 - 1.3 8.7 5.3 2.4 7.9 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Lge1 PF11488.8 KFQ96764.1 - 1.4 9.2 8.9 0.89 9.8 0.1 3.0 3 1 0 3 3 2 0 Transcriptional regulatory protein LGE1 Phage_GPO PF05929.11 KFQ96764.1 - 1.6 8.3 8.3 5.5 6.5 5.6 2.7 1 1 2 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Herpes_UL25 PF01499.16 KFQ96764.1 - 1.6 7.2 5.3 0.79 8.2 1.5 1.9 1 1 0 2 2 2 0 Herpesvirus UL25 family COG5 PF10392.9 KFQ96764.1 - 1.7 8.9 9.5 2.7 8.2 0.7 2.7 2 1 0 2 2 2 0 Golgi transport complex subunit 5 DUF148 PF02520.17 KFQ96764.1 - 1.8 8.7 11.3 0.066 13.3 1.5 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF148 Ead_Ea22 PF13935.6 KFQ96764.1 - 1.9 9.2 9.8 0.53 10.9 2.3 2.6 2 1 0 2 2 2 0 Ead/Ea22-like protein FlaC_arch PF05377.11 KFQ96764.1 - 2 8.9 15.6 4.5 7.7 2.7 4.2 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 KFQ96764.1 - 3.3 7.9 16.0 1.9 8.7 6.1 3.1 1 1 2 3 3 2 0 Fibrinogen alpha/beta chain family DUF4404 PF14357.6 KFQ96764.1 - 3.5 8.3 8.6 1.9 9.2 2.7 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) DUF4600 PF15372.6 KFQ96764.1 - 4.7 7.7 12.1 0.62 10.5 5.8 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4600) DUF1664 PF07889.12 KFQ96764.1 - 4.9 7.2 13.7 6.9 6.7 3.6 3.5 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 KFQ96764.1 - 6 6.0 12.7 2.2 7.5 5.7 2.3 1 1 0 2 2 2 0 TMPIT-like protein DUF883 PF05957.13 KFQ96764.1 - 6.6 7.4 8.3 7.5 7.2 1.1 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) COG2 PF06148.11 KFQ96764.1 - 8 6.6 13.2 8.7 6.4 2.8 3.5 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Uso1_p115_C PF04871.13 KFQ96764.1 - 8.4 6.8 19.8 0.46 10.9 7.6 3.0 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region WBS_methylT PF12589.8 KFQ96765.1 - 1.7e-20 73.5 5.5 2.5e-20 73.0 5.5 1.2 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KFQ96765.1 - 2e-10 41.2 0.0 3.3e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFQ96765.1 - 1.2e-09 38.8 0.0 2.1e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFQ96765.1 - 0.00021 21.2 0.0 0.00037 20.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFQ96765.1 - 0.00022 21.9 0.0 0.00041 21.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFQ96765.1 - 0.035 13.9 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Mod_r PF07200.13 KFQ96766.1 - 2.1e-12 47.3 0.4 3.1e-12 46.8 0.1 1.4 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Fibrinogen_C PF00147.18 KFQ96767.1 - 3e-44 151.4 3.4 3.5e-44 151.3 3.4 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain SRF-TF PF00319.18 KFQ96769.1 - 1.2e-19 69.5 0.5 2e-19 68.8 0.5 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C PF12347.8 KFQ96769.1 - 8.1e-18 64.2 0.1 3.4e-17 62.2 0.1 2.1 1 0 0 1 1 1 1 Holliday junction regulator protein family C-terminal repeat EF-hand_7 PF13499.6 KFQ96770.1 - 2.6e-26 91.9 11.6 3.9e-15 56.1 2.5 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFQ96770.1 - 6.9e-26 87.8 19.5 6.5e-09 34.7 0.9 4.5 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 KFQ96770.1 - 5.5e-23 78.9 12.5 3.3e-06 26.6 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KFQ96770.1 - 8.8e-16 57.5 14.2 5.3e-11 42.2 0.9 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KFQ96770.1 - 2.2e-12 45.9 12.3 7.6e-05 22.0 0.9 4.7 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 KFQ96770.1 - 2.2e-09 37.5 0.8 0.00014 22.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KFQ96770.1 - 0.00019 21.3 6.3 0.047 13.6 0.3 2.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 KFQ96770.1 - 0.00037 20.5 1.0 0.64 9.9 0.0 3.8 1 1 3 4 4 4 1 Caleosin related protein EF-hand_14 PF17959.1 KFQ96770.1 - 0.0053 17.1 3.3 0.24 11.8 0.2 2.5 1 1 1 2 2 2 1 EF-hand domain HTH_40 PF14493.6 KFQ96770.1 - 0.0057 17.1 2.6 0.57 10.7 0.1 2.3 1 1 1 2 2 2 2 Helix-turn-helix domain SPARC_Ca_bdg PF10591.9 KFQ96770.1 - 0.015 15.6 5.7 0.36 11.2 1.6 2.3 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region UBA_2 PF08587.11 KFQ96770.1 - 0.043 13.9 0.2 2.2 8.4 0.0 2.8 2 1 0 2 2 2 0 Ubiquitin associated domain (UBA) MgtE_N PF03448.17 KFQ96770.1 - 0.11 13.1 0.7 0.11 13.1 0.7 2.5 1 1 2 3 3 3 0 MgtE intracellular N domain MH2 PF03166.14 KFQ96772.1 - 6e-76 254.8 1.4 8.4e-76 254.3 1.4 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 KFQ96772.1 - 2.6e-42 143.2 0.3 5.9e-42 142.1 0.3 1.6 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.9 KFQ96772.1 - 0.00015 21.6 0.0 0.00025 20.9 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 DUF4223 PF13978.6 KFQ96772.1 - 0.13 12.2 0.8 0.27 11.2 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) Fasciclin PF02469.22 KFQ96773.1 - 1.2e-107 355.3 4.6 1.4e-32 112.6 0.2 4.1 4 0 0 4 4 4 4 Fasciclin domain DUF5618 PF18498.1 KFQ96773.1 - 0.07 13.3 0.0 25 5.1 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5618) Fibrillin_U_N PF18193.1 KFQ96773.1 - 0.37 10.9 1.8 1 9.5 1.8 1.7 1 0 0 1 1 1 0 Fibrillin 1 unique N-terminal domain F-box-like PF12937.7 KFQ96774.1 - 5e-12 45.5 1.2 1.3e-11 44.2 0.7 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFQ96774.1 - 1.3e-10 40.9 3.1 1.3e-10 40.9 0.9 2.3 2 0 0 2 2 2 1 F-box domain F-box_5 PF18511.1 KFQ96774.1 - 0.036 13.6 0.1 0.074 12.6 0.1 1.5 1 0 0 1 1 1 0 F-box Humanin PF15040.6 KFQ96775.1 - 0.092 12.2 0.2 0.092 12.2 0.2 1.8 2 0 0 2 2 2 0 Humanin family Mito_carr PF00153.27 KFQ96776.1 - 3.7e-57 190.2 1.2 3.8e-21 74.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF787 PF05619.11 KFQ96776.1 - 0.021 14.0 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF787) DUF3082 PF11282.8 KFQ96776.1 - 0.12 12.6 0.5 5 7.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3082) Ion_trans PF00520.31 KFQ96778.1 - 1.5e-42 145.6 13.3 1.8e-42 145.3 13.3 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFQ96778.1 - 4.5e-27 94.2 0.0 1.1e-26 93.0 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFQ96778.1 - 1.2e-09 38.0 6.2 1.2e-09 38.0 6.2 2.6 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.5 KFQ96778.1 - 0.0014 18.7 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain MgtE PF01769.16 KFQ96778.1 - 0.14 12.6 0.2 0.14 12.6 0.2 2.8 2 1 1 3 3 3 0 Divalent cation transporter PKD_channel PF08016.12 KFQ96778.1 - 0.81 8.3 5.6 1.6 7.3 1.8 2.1 1 1 1 2 2 2 0 Polycystin cation channel Lig_chan-Glu_bd PF10613.9 KFQ96779.1 - 2.4e-26 92.2 0.0 3.2e-25 88.5 0.0 2.1 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.28 KFQ96779.1 - 3.8e-17 62.4 0.0 5.7e-13 48.7 0.0 2.2 1 1 1 2 2 2 2 Receptor family ligand binding region Lig_chan PF00060.26 KFQ96779.1 - 8.1e-13 48.5 4.3 1.3e-12 47.7 4.3 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 KFQ96779.1 - 3.6e-07 29.8 0.0 6.9e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 MatE PF01554.18 KFQ96779.1 - 0.029 14.0 0.3 0.054 13.1 0.3 1.4 1 0 0 1 1 1 0 MatE MoaE PF02391.17 KFQ96782.1 - 4.5e-40 136.5 0.2 5.6e-40 136.1 0.2 1.1 1 0 0 1 1 1 1 MoaE protein VWA PF00092.28 KFQ96783.1 - 7.2e-41 140.3 0.1 1.5e-40 139.3 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Integrin_alpha2 PF08441.12 KFQ96783.1 - 3.2e-35 121.9 6.3 5.5e-35 121.2 6.3 1.3 1 0 0 1 1 1 1 Integrin alpha VWA_2 PF13519.6 KFQ96783.1 - 1.6e-14 54.4 0.0 4.2e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain FG-GAP PF01839.23 KFQ96783.1 - 6.4e-12 45.4 15.0 3.1e-06 27.2 0.4 4.2 4 0 0 4 4 4 2 FG-GAP repeat FG-GAP_2 PF14312.6 KFQ96783.1 - 1.1e-05 25.6 9.0 0.015 15.5 0.0 5.6 6 0 0 6 6 6 2 FG-GAP repeat Integrin_alpha PF00357.20 KFQ96783.1 - 0.00037 20.3 0.7 0.00087 19.1 0.7 1.7 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region VCBS PF13517.6 KFQ96783.1 - 0.0041 17.7 9.2 0.96 10.1 0.1 4.4 5 0 0 5 5 5 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Ion_trans PF00520.31 KFQ96785.1 - 7.2e-51 172.8 3.6 8.9e-51 172.5 3.6 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFQ96785.1 - 1.8e-21 76.3 0.0 3e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFQ96785.1 - 1.2e-12 47.6 10.8 1.3e-12 47.5 7.9 2.4 2 0 0 2 2 2 1 Ion channel DUF423 PF04241.15 KFQ96785.1 - 0.093 13.0 1.9 0.45 10.7 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF423) PKD_channel PF08016.12 KFQ96785.1 - 0.19 10.3 5.8 0.061 12.0 1.8 1.9 1 1 1 2 2 2 0 Polycystin cation channel Lig_chan PF00060.26 KFQ96785.1 - 0.35 10.7 1.5 3 7.7 0.7 2.1 2 0 0 2 2 2 0 Ligand-gated ion channel RRM_1 PF00076.22 KFQ96786.1 - 3.4e-13 49.2 0.0 3.9e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_POL_M_15KD PF02150.16 KFQ96792.1 - 6.2e-08 32.4 0.9 6.2e-08 32.4 0.9 1.5 1 1 0 1 1 1 1 RNA polymerases M/15 Kd subunit bZIP_2 PF07716.15 KFQ96794.1 - 0.00087 19.3 2.8 0.0013 18.8 2.8 1.2 1 0 0 1 1 1 1 Basic region leucine zipper NRBF2 PF08961.10 KFQ96794.1 - 0.0027 17.3 1.0 0.0029 17.2 1.0 1.0 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator TSC22 PF01166.18 KFQ96794.1 - 0.0044 17.3 1.1 0.0047 17.2 1.1 1.2 1 0 0 1 1 1 1 TSC-22/dip/bun family bZIP_1 PF00170.21 KFQ96794.1 - 0.014 15.5 2.5 0.014 15.4 2.5 1.2 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.15 KFQ96794.1 - 0.02 14.6 1.9 0.022 14.5 1.9 1.1 1 0 0 1 1 1 0 Septum formation initiator Phage_Gp23 PF10669.9 KFQ96794.1 - 0.03 14.7 0.2 0.032 14.5 0.2 1.1 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) ORF6C PF10552.9 KFQ96794.1 - 0.04 14.0 0.7 0.04 14.0 0.7 1.0 1 0 0 1 1 1 0 ORF6C domain HSBP1 PF06825.12 KFQ96794.1 - 0.042 13.7 0.1 0.054 13.4 0.1 1.3 1 0 0 1 1 1 0 Heat shock factor binding protein 1 BMFP PF04380.13 KFQ96794.1 - 0.051 14.1 1.8 0.065 13.7 1.8 1.2 1 0 0 1 1 1 0 Membrane fusogenic activity IQ_SEC7_PH PF16453.5 KFQ96795.1 - 1.8e-67 225.6 2.1 4e-67 224.4 0.0 2.5 3 0 0 3 3 3 1 PH domain Sec7 PF01369.20 KFQ96795.1 - 4e-63 212.4 0.1 8.9e-63 211.3 0.0 1.7 2 0 0 2 2 2 1 Sec7 domain Parathyroid PF01279.17 KFQ96797.1 - 4.7e-38 130.1 0.5 1e-37 129.0 0.5 1.5 1 0 0 1 1 1 1 Parathyroid hormone family RRP14 PF15459.6 KFQ96797.1 - 1.1 9.9 11.4 1.9 9.1 11.4 1.3 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 Kelch_1 PF01344.25 KFQ96798.1 - 1.3e-28 98.3 5.0 3.2e-09 36.2 0.0 5.2 5 1 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 KFQ96798.1 - 2.3e-24 84.8 3.6 1.2e-07 31.8 0.0 6.1 5 2 1 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KFQ96798.1 - 2.1e-11 43.3 0.8 0.0091 15.9 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 KFQ96798.1 - 3.4e-11 43.1 3.0 0.00054 20.2 0.0 5.1 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KFQ96798.1 - 1.8e-10 40.5 1.2 8.6e-05 22.4 0.0 4.4 4 0 0 4 4 4 2 Kelch motif BTB PF00651.31 KFQ96798.1 - 0.00013 22.2 0.0 0.0029 17.8 0.0 2.4 1 1 1 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.6 KFQ96798.1 - 0.00025 21.0 6.6 0.6 10.2 0.0 5.4 5 2 0 5 5 5 2 Galactose oxidase, central domain BACK PF07707.15 KFQ96798.1 - 0.015 15.4 0.1 0.034 14.3 0.1 1.6 1 0 0 1 1 1 0 BTB And C-terminal Kelch Neuropeptide_S PF14993.6 KFQ96798.1 - 0.022 14.6 0.0 6.3 6.7 0.0 2.5 2 0 0 2 2 2 0 Neuropeptide S precursor protein BILBO1_N PF18281.1 KFQ96798.1 - 0.069 13.6 0.3 30 5.1 0.0 3.8 4 0 0 4 4 4 0 BILBO1 N-terminal domain MRP-S28 PF10213.9 KFQ96800.1 - 1.2e-18 67.8 0.2 2e-18 67.0 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Ion_trans PF00520.31 KFQ96802.1 - 1.6e-27 96.3 10.8 2.2e-27 95.9 10.8 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFQ96802.1 - 9.7e-12 44.7 5.1 9.7e-12 44.7 5.1 2.4 2 1 0 2 2 2 1 Ion channel CD225 PF04505.12 KFQ96802.1 - 0.025 14.7 0.2 0.57 10.4 0.1 3.0 2 0 0 2 2 2 0 Interferon-induced transmembrane protein PsbW PF07123.12 KFQ96802.1 - 0.13 12.3 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) TILa PF12714.7 KFQ96806.1 - 4.4e-17 61.8 131.9 0.025 14.5 2.7 11.1 6 5 5 11 11 11 11 TILa domain FOLN PF09289.10 KFQ96806.1 - 4.9e-13 49.0 145.4 0.0018 18.4 4.6 14.9 12 5 5 17 17 17 7 Follistatin/Osteonectin-like EGF domain CBM_1 PF00734.18 KFQ96806.1 - 4.7e-12 45.7 60.3 0.38 10.8 1.0 11.9 11 0 0 11 11 11 11 Fungal cellulose binding domain zf_CCCH_4 PF18345.1 KFQ96806.1 - 2.3e-06 27.4 34.3 27 5.0 0.1 11.6 11 0 0 11 11 11 5 Zinc finger domain DUF4951 PF16309.5 KFQ96806.1 - 0.0085 16.1 0.0 2.9e+02 1.6 0.0 4.9 5 0 0 5 5 5 0 Domian of unknown function (DUF4951) FOLN PF09289.10 KFQ96807.1 - 1.4e-19 69.9 108.8 0.0022 18.1 1.6 12.0 12 0 0 12 12 12 11 Follistatin/Osteonectin-like EGF domain TILa PF12714.7 KFQ96807.1 - 4.1e-16 58.7 115.5 0.023 14.7 2.9 11.1 5 5 6 11 11 11 10 TILa domain zf_CCCH_4 PF18345.1 KFQ96807.1 - 0.00035 20.5 41.1 27 5.0 0.1 11.6 11 0 0 11 11 11 0 Zinc finger domain DUF4951 PF16309.5 KFQ96807.1 - 0.0013 18.7 1.6 1.2e+02 2.9 0.0 6.1 6 1 2 8 8 8 0 Domian of unknown function (DUF4951) CBM_1 PF00734.18 KFQ96807.1 - 0.0013 18.6 69.3 0.37 10.8 1.0 11.7 11 0 0 11 11 11 6 Fungal cellulose binding domain DUF4316 PF14195.6 KFQ96807.1 - 0.21 11.3 0.1 24 4.8 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4316) Dicty_spore_N PF04562.12 KFQ96807.1 - 0.7 10.6 83.3 0.23 12.1 9.2 6.1 1 1 5 6 6 6 0 Dictyostelium spore coat protein, N terminus TILa PF12714.7 KFQ96808.1 - 3.9e-22 78.0 117.8 0.025 14.5 4.4 11.1 5 5 6 11 11 11 11 TILa domain FOLN PF09289.10 KFQ96808.1 - 1.5e-12 47.5 112.2 0.06 13.5 5.5 11.7 11 1 0 11 11 11 11 Follistatin/Osteonectin-like EGF domain CBM_1 PF00734.18 KFQ96808.1 - 0.0099 15.8 73.2 9.4 6.3 1.1 12.2 11 0 0 11 11 11 11 Fungal cellulose binding domain S36_mt PF10937.8 KFQ96810.1 - 0.0084 17.7 0.1 0.0088 17.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial Med24_N PF11277.8 KFQ96813.1 - 0 1260.7 20.8 0 1260.5 20.8 1.0 1 0 0 1 1 1 1 Mediator complex subunit 24 N-terminal DUF5314 PF17241.2 KFQ96813.1 - 0.052 13.2 0.2 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5314) Med8 PF10232.9 KFQ96813.1 - 0.1 12.1 2.1 0.2 11.2 2.1 1.4 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 GCSF PF16647.5 KFQ96814.1 - 1.3e-22 80.2 0.1 2e-22 79.7 0.1 1.3 1 1 0 1 1 1 1 Granulocyte colony-stimulating factor IL11 PF07400.11 KFQ96814.1 - 0.003 17.2 0.0 0.0043 16.7 0.0 1.3 1 1 0 1 1 1 1 Interleukin 11 IL6 PF00489.17 KFQ96814.1 - 0.013 15.1 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family ORMDL PF04061.14 KFQ96815.1 - 4.3e-54 182.0 4.6 4.9e-54 181.8 4.6 1.0 1 0 0 1 1 1 1 ORMDL family LRR_8 PF13855.6 KFQ96817.1 - 3.4e-17 61.9 4.6 3.8e-11 42.6 0.0 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFQ96817.1 - 1.1e-06 28.9 5.1 0.13 12.7 0.1 3.5 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) DUF3700 PF12481.8 KFQ96817.1 - 7.3e-05 22.3 0.1 0.00024 20.6 0.0 1.8 3 0 0 3 3 3 1 Aluminium induced protein LRRNT PF01462.18 KFQ96817.1 - 0.0055 16.3 0.1 0.016 14.8 0.1 1.9 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 KFQ96817.1 - 0.031 14.3 6.2 2.1 8.6 0.2 3.4 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 KFQ96817.1 - 0.15 12.7 11.3 0.76 10.6 0.5 4.7 4 1 0 4 4 4 0 Leucine Rich Repeat Sp38 PF07354.12 KFQ96818.1 - 7.7e-79 263.2 9.8 1.1e-78 262.8 9.8 1.2 1 0 0 1 1 1 1 Zona-pellucida-binding protein (Sp38) HEPN_RnaseLS PF18869.1 KFQ96818.1 - 0.033 14.3 0.1 11 6.1 0.4 2.2 1 1 1 2 2 2 0 RnaseLS-like HEPN zf-H2C2_2 PF13465.6 KFQ96819.1 - 7.8e-25 86.2 28.1 4.7e-07 30.0 3.8 5.7 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ96819.1 - 1.5e-16 59.8 38.5 7.5e-06 26.1 0.4 6.7 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ96819.1 - 3.4e-12 46.1 39.0 0.00019 22.0 0.3 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFQ96819.1 - 0.00063 19.4 32.4 0.0027 17.4 0.1 5.4 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KFQ96819.1 - 0.0043 16.8 0.2 0.0043 16.8 0.2 4.7 5 1 0 5 5 4 1 zinc-finger C2H2-type GAGA PF09237.11 KFQ96819.1 - 0.067 13.0 2.6 0.1 12.4 0.1 2.5 1 1 0 2 2 2 0 GAGA factor zf-C2HE PF16278.5 KFQ96819.1 - 0.083 13.4 16.4 0.56 10.7 0.8 4.4 2 1 2 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 KFQ96819.1 - 0.11 12.5 40.3 0.5 10.4 0.1 6.5 6 0 0 6 6 6 0 C2H2-type zinc finger DUF3268 PF11672.8 KFQ96819.1 - 0.19 12.1 0.3 0.19 12.1 0.3 3.2 3 1 0 3 3 3 0 zinc-finger-containing domain zf-C2H2_jaz PF12171.8 KFQ96819.1 - 0.62 10.4 23.7 2.3 8.6 0.3 5.5 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-RING_7 PF02591.15 KFQ96819.1 - 3.1 8.1 9.4 30 4.9 0.1 4.1 4 0 0 4 4 4 0 C4-type zinc ribbon domain AKAP95 PF04988.12 KFQ96819.1 - 6.9 6.9 8.0 3.8 7.7 0.4 2.6 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Ribosomal_S2 PF00318.20 KFQ96822.1 - 0.086 12.1 0.0 3 7.0 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S2 DUF373 PF04123.13 KFQ96822.1 - 0.36 10.2 1.2 0.52 9.7 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF373) zf-CCHC PF00098.23 KFQ96823.1 - 6.8e-08 32.2 47.7 6.5e-06 26.0 0.8 5.3 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_3 PF13917.6 KFQ96823.1 - 0.0017 18.3 31.8 0.0023 17.8 0.6 5.1 2 1 3 5 5 5 3 Zinc knuckle zf-CCHC_2 PF13696.6 KFQ96823.1 - 0.0082 15.9 1.6 0.0082 15.9 1.6 5.4 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_4 PF14392.6 KFQ96823.1 - 0.22 11.3 34.9 0.58 9.9 3.6 5.1 4 1 1 5 5 5 0 Zinc knuckle 2-Hacid_dh_C PF02826.19 KFQ96824.1 - 2.1e-60 203.1 0.0 2.6e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFQ96824.1 - 1.4e-17 63.6 0.0 1.6e-17 63.5 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 KFQ96824.1 - 9.5e-07 29.3 0.0 1.9e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KFQ96824.1 - 2.4e-06 27.8 0.0 3.8e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KFQ96824.1 - 0.032 13.8 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ThiF PF00899.21 KFQ96824.1 - 0.11 11.8 0.2 0.27 10.5 0.2 1.5 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.20 KFQ96824.1 - 0.15 12.2 0.0 0.29 11.2 0.0 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KFQ96824.1 - 0.17 12.1 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain BTB PF00651.31 KFQ96825.1 - 2.4e-29 101.8 1.1 5.2e-29 100.7 1.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFQ96825.1 - 6.4e-05 23.2 9.7 0.00086 19.6 0.6 3.6 3 0 0 3 3 3 2 Zinc-finger double domain DUF3342 PF11822.8 KFQ96825.1 - 0.012 15.7 0.2 0.027 14.7 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) Rota_NS35 PF02509.14 KFQ96825.1 - 0.1 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Rotavirus non-structural protein 35 zf-C2H2_4 PF13894.6 KFQ96825.1 - 0.69 10.9 14.9 0.13 13.2 4.5 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger RNA_pol_I_A49 PF06870.12 KFQ96826.1 - 8.4e-81 271.8 1.1 3.7e-80 269.6 1.1 1.7 1 1 0 1 1 1 1 A49-like RNA polymerase I associated factor RgpF PF05045.12 KFQ96826.1 - 0.01 14.6 0.3 0.014 14.2 0.3 1.1 1 0 0 1 1 1 0 Rhamnan synthesis protein F Beta_helix PF13229.6 KFQ96827.1 - 1.2e-46 158.4 48.9 3.3e-19 69.3 17.3 5.9 3 2 3 6 6 6 6 Right handed beta helix region NosD PF05048.13 KFQ96827.1 - 1.1e-32 113.3 29.2 9.3e-13 48.0 2.4 4.8 3 2 2 5 5 5 4 Periplasmic copper-binding protein (NosD) F-box-like PF12937.7 KFQ96827.1 - 3.1e-09 36.6 5.1 6.7e-09 35.5 5.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFQ96827.1 - 2.4e-07 30.5 2.7 6.5e-07 29.1 2.7 1.8 1 0 0 1 1 1 1 F-box domain Pentapeptide_4 PF13599.6 KFQ96827.1 - 0.11 12.7 4.2 0.22 11.7 2.9 2.2 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) F-box_5 PF18511.1 KFQ96827.1 - 0.11 12.0 0.2 0.23 11.0 0.2 1.4 1 0 0 1 1 1 0 F-box Mito_carr PF00153.27 KFQ96828.1 - 5.1e-34 116.1 0.2 3.9e-11 42.7 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 KFQ96829.1 - 4.1e-12 46.4 11.9 0.0004 21.1 0.8 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ96829.1 - 7.7e-05 22.9 0.0 7.2 7.0 0.1 4.3 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.6 KFQ96829.1 - 0.043 13.7 0.1 8 6.4 0.0 2.9 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal CMD PF02627.20 KFQ96830.1 - 1.5e-13 50.6 0.1 1.1e-12 47.9 0.1 2.0 1 1 1 2 2 2 1 Carboxymuconolactone decarboxylase family PA26 PF04636.13 KFQ96830.1 - 0.0097 14.9 0.0 0.013 14.5 0.0 1.2 1 1 0 1 1 1 1 PA26 p53-induced protein (sestrin) DUF1961 PF09224.11 KFQ96830.1 - 0.093 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1961) tRNA_m1G_MT PF01746.21 KFQ96831.1 - 3.8e-23 82.2 0.0 4.1e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase DUF543 PF04418.12 KFQ96831.1 - 0.18 11.8 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF543) FERM_M PF00373.18 KFQ96832.1 - 3.1e-14 53.4 0.2 8.1e-14 52.0 0.2 1.8 1 0 0 1 1 1 1 FERM central domain Jak1_Phl PF17887.1 KFQ96832.1 - 0.00015 21.8 0.1 0.0004 20.4 0.1 1.7 1 0 0 1 1 1 1 Jak1 pleckstrin homology-like domain I_LWEQ PF01608.17 KFQ96832.1 - 0.15 12.3 1.2 0.38 11.0 1.2 1.6 1 0 0 1 1 1 0 I/LWEQ domain HMMR_N PF15905.5 KFQ96834.1 - 0.0052 16.3 0.9 0.006 16.1 0.9 1.0 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Laminin_II PF06009.12 KFQ96834.1 - 0.039 14.0 0.1 0.047 13.7 0.1 1.1 1 0 0 1 1 1 0 Laminin Domain II R3H PF01424.22 KFQ96835.1 - 2.4e-18 65.9 0.1 4.9e-18 64.9 0.1 1.6 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 KFQ96835.1 - 2.7e-12 46.5 99.5 2.2e-05 24.4 11.7 13.5 13 1 0 13 13 13 7 NF-X1 type zinc finger AA_permease PF00324.21 KFQ96836.1 - 1e-49 169.4 17.4 1.2e-38 132.9 5.3 2.1 2 0 0 2 2 2 2 Amino acid permease SLC12 PF03522.15 KFQ96836.1 - 1.6e-46 159.2 8.7 1.5e-16 60.5 3.6 3.3 2 1 1 3 3 3 3 Solute carrier family 12 PRA1 PF03208.19 KFQ96836.1 - 2.1 8.0 11.0 0.27 10.9 0.2 2.6 2 0 0 2 2 2 0 PRA1 family protein zf-H2C2_2 PF13465.6 KFQ96837.1 - 5.5e-11 42.4 13.4 7.5e-07 29.3 0.2 3.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ96837.1 - 3.8e-10 39.6 11.7 2.5e-05 24.5 0.7 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFQ96837.1 - 8.9e-07 28.8 1.4 2.4e-06 27.4 0.2 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KFQ96837.1 - 5.7e-06 26.7 3.7 0.00042 20.9 0.4 3.1 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ96837.1 - 9.6e-05 22.6 0.2 0.0015 18.7 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFQ96837.1 - 0.00012 22.4 0.6 0.00053 20.3 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFQ96837.1 - 0.016 15.5 2.2 0.074 13.4 2.1 1.9 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-CRD PF17979.1 KFQ96837.1 - 0.035 14.2 8.0 2.3 8.3 8.0 2.1 1 1 0 1 1 1 0 Cysteine rich domain with multizinc binding regions Collagen PF01391.18 KFQ96841.1 - 3.2e-200 648.1 771.7 6.3e-10 38.7 25.2 27.4 5 4 21 26 26 26 26 Collagen triple helix repeat (20 copies) C4 PF01413.19 KFQ96841.1 - 8.5e-83 274.1 2.7 4.9e-44 149.2 0.3 2.1 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Collagen PF01391.18 KFQ96842.1 - 5.9e-29 99.6 78.1 6.4e-10 38.6 25.9 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) C4 PF01413.19 KFQ96843.1 - 4.8e-84 278.1 1.5 1e-45 154.7 0.1 2.0 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Integrase_H2C2 PF17921.1 KFQ96843.1 - 0.091 12.9 1.3 10 6.3 0.1 2.4 2 0 0 2 2 2 0 Integrase zinc binding domain Ras PF00071.22 KFQ96844.1 - 9.6e-14 51.3 0.0 3.1e-13 49.6 0.0 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFQ96844.1 - 2.2e-05 24.6 0.0 3.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ96844.1 - 0.02 14.4 0.0 0.028 13.9 0.0 1.3 1 1 0 1 1 1 0 ADP-ribosylation factor family Carb_kinase PF01256.17 KFQ96845.1 - 6e-56 189.6 0.0 7.5e-56 189.3 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 KFQ96845.1 - 0.015 14.7 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family Suc_Fer-like PF06999.12 KFQ96845.1 - 0.05 13.5 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 Sucrase/ferredoxin-like tRNA-synt_1e PF01406.19 KFQ96846.1 - 1.5e-100 336.4 0.3 2e-100 336.1 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KFQ96846.1 - 3.6e-08 32.6 0.9 0.00022 20.1 0.1 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KFQ96846.1 - 0.00026 19.4 0.0 0.00035 19.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.11 KFQ96846.1 - 0.0017 18.8 0.0 0.0046 17.4 0.0 1.8 1 0 0 1 1 1 1 DALR domain tRNA-synt_1f PF01921.18 KFQ96846.1 - 0.045 12.7 0.5 0.086 11.7 0.1 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (K) ING PF12998.7 KFQ96847.1 - 3e-30 104.8 5.2 3e-30 104.8 5.2 2.0 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KFQ96847.1 - 1.9e-06 27.7 8.4 4.6e-06 26.4 8.4 1.7 1 0 0 1 1 1 1 PHD-finger SRP-alpha_N PF04086.13 KFQ96847.1 - 0.0012 18.9 13.3 0.0018 18.3 13.3 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal DUF4661 PF15576.6 KFQ96847.1 - 0.013 15.5 4.1 0.019 14.9 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) PHD_2 PF13831.6 KFQ96847.1 - 0.013 15.1 3.1 0.024 14.2 3.1 1.4 1 0 0 1 1 1 0 PHD-finger ZYG-11_interact PF05884.12 KFQ96847.1 - 0.061 12.7 0.5 0.088 12.2 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 NPR3 PF03666.13 KFQ96847.1 - 0.074 11.8 6.0 0.12 11.2 6.0 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SF3A3 PF16837.5 KFQ96847.1 - 0.091 13.3 0.3 0.2 12.2 0.3 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-HC5HC2H PF13771.6 KFQ96847.1 - 0.1 12.9 3.1 0.4 11.0 3.0 2.3 1 1 0 1 1 1 0 PHD-like zinc-binding domain CDC45 PF02724.14 KFQ96847.1 - 0.26 9.5 9.6 0.25 9.6 9.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Virul_Fac PF10139.9 KFQ96847.1 - 0.84 7.8 10.4 1.1 7.4 10.4 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor ALMT PF11744.8 KFQ96847.1 - 1.2 7.9 8.2 1.6 7.5 8.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Zip PF02535.22 KFQ96847.1 - 1.5 8.0 4.7 1.6 7.9 4.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 KFQ96847.1 - 1.6 8.5 13.0 2.4 7.9 13.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 zf-C4pol PF14260.6 KFQ96847.1 - 1.6 9.2 10.1 5.4 7.5 0.9 3.6 3 1 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta Presenilin PF01080.17 KFQ96847.1 - 2.5 6.8 11.9 3.4 6.3 11.9 1.2 1 0 0 1 1 1 0 Presenilin Ank_2 PF12796.7 KFQ96848.1 - 1.9e-24 86.0 0.6 1.1e-12 48.4 0.3 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ96848.1 - 4.2e-16 59.1 0.3 9.1e-08 32.5 0.0 3.6 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFQ96848.1 - 6.8e-12 45.4 0.3 9.4e-07 29.0 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KFQ96848.1 - 1.7e-11 44.0 0.7 0.00028 21.2 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KFQ96848.1 - 2.9e-09 36.4 0.0 0.0049 17.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat RhoGEF67_u2 PF16614.5 KFQ96849.1 - 1.2e-50 170.1 4.3 1.2e-50 170.1 4.3 2.7 2 1 0 2 2 2 1 Unstructured region two on RhoGEF 6 and 7 betaPIX_CC PF16523.5 KFQ96849.1 - 3.3e-41 139.0 10.1 3.3e-41 139.0 10.1 3.1 4 0 0 4 4 4 1 betaPIX coiled coil RhoGEF PF00621.20 KFQ96849.1 - 8e-32 110.9 0.5 8e-32 110.9 0.5 2.1 2 0 0 2 2 2 1 RhoGEF domain SH3_2 PF07653.17 KFQ96849.1 - 5e-18 64.5 0.2 1.1e-17 63.5 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFQ96849.1 - 2.9e-17 62.2 0.1 5.6e-17 61.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFQ96849.1 - 1.2e-16 60.1 0.2 2.2e-16 59.2 0.2 1.5 1 0 0 1 1 1 1 SH3 domain RhoGEF67_u1 PF16615.5 KFQ96849.1 - 3.4e-16 59.5 2.6 3.4e-16 59.5 2.6 3.4 4 0 0 4 4 3 1 Unstructured region one on RhoGEF 6 and 7 PH PF00169.29 KFQ96849.1 - 4.2e-09 36.9 0.0 1.1e-08 35.6 0.0 1.7 1 0 0 1 1 1 1 PH domain AKNA PF12443.8 KFQ96849.1 - 0.072 13.7 4.9 0.69 10.6 0.1 3.1 2 0 0 2 2 2 0 AT-hook-containing transcription factor GlutR_dimer PF00745.20 KFQ96849.1 - 0.22 12.0 3.5 0.72 10.3 3.5 1.9 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain TCTP PF00838.17 KFQ96849.1 - 0.3 11.4 3.1 1.1 9.6 0.9 2.5 2 0 0 2 2 2 0 Translationally controlled tumour protein CENP-Q PF13094.6 KFQ96849.1 - 0.59 10.3 12.6 0.8 9.9 4.7 3.2 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Cep57_MT_bd PF06657.13 KFQ96849.1 - 3.9 8.0 9.1 2 9.0 4.1 2.9 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 FCH PF00611.23 KFQ96849.1 - 6.4 7.1 7.9 0.94 9.8 0.4 3.2 3 0 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain GCP_C_terminal PF04130.13 KFQ96850.1 - 0.00038 20.0 0.1 0.00044 19.8 0.1 1.0 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_C_terminal PF04130.13 KFQ96851.1 - 3.3e-83 279.7 10.8 3.3e-83 279.7 10.8 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KFQ96851.1 - 1e-81 274.9 0.5 1e-81 274.9 0.5 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal Ig_3 PF13927.6 KFQ96853.1 - 3.3e-31 107.7 3.2 7.5e-11 42.5 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFQ96853.1 - 1.6e-23 82.6 1.6 5.7e-08 32.7 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KFQ96853.1 - 1.3e-22 79.9 0.8 9.9e-07 29.0 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFQ96853.1 - 1.8e-21 76.1 3.3 2e-06 27.9 0.5 3.5 3 1 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.12 KFQ96853.1 - 8.4e-17 61.0 2.9 1.9e-16 59.9 0.2 2.6 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFQ96853.1 - 2.1e-13 50.4 4.8 1.5e-07 31.6 0.0 4.0 2 1 1 3 3 3 3 Immunoglobulin V-set domain Ig_5 PF16681.5 KFQ96853.1 - 4.1e-07 30.3 2.3 0.03 14.7 0.0 4.1 4 1 0 4 4 4 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 KFQ96853.1 - 1.3e-06 28.7 1.0 9.7e-06 25.9 0.0 2.6 2 1 0 2 2 2 1 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 KFQ96853.1 - 0.003 17.6 0.0 4.8 7.3 0.0 2.7 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFQ96853.1 - 0.011 15.2 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain Syndecan PF01034.20 KFQ96853.1 - 0.016 15.1 0.1 0.24 11.3 0.0 2.7 3 0 0 3 3 3 0 Syndecan domain C2-set PF05790.15 KFQ96853.1 - 0.027 14.7 5.5 3.4 7.9 0.8 3.7 4 1 0 4 4 4 0 Immunoglobulin C2-set domain Pentaxin PF00354.17 KFQ96854.1 - 1e-75 253.7 0.0 1.1e-75 253.6 0.0 1.0 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.6 KFQ96854.1 - 2e-07 31.2 0.0 2.7e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DSPc PF00782.20 KFQ96855.1 - 3.7e-11 43.0 0.0 3.7e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFQ96855.1 - 1.5e-09 38.2 0.0 2.4e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KFQ96855.1 - 1.2e-08 34.8 0.0 1.3e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFQ96855.1 - 0.0029 17.6 0.0 0.0035 17.3 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Ig_3 PF13927.6 KFQ96856.1 - 3.1e-52 175.1 0.0 2.5e-13 50.4 0.0 5.7 6 0 0 6 6 6 5 Immunoglobulin domain I-set PF07679.16 KFQ96856.1 - 5.9e-41 138.4 0.0 5.5e-11 42.4 0.0 6.0 6 1 0 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.6 KFQ96856.1 - 3.9e-33 113.6 0.0 1.3e-08 35.0 0.0 5.4 5 1 0 5 5 5 4 Immunoglobulin domain ig PF00047.25 KFQ96856.1 - 2.6e-32 110.9 0.1 1.5e-08 34.7 0.0 5.7 5 1 0 5 5 5 3 Immunoglobulin domain fn3 PF00041.21 KFQ96856.1 - 6.3e-21 74.5 0.0 7.2e-10 39.1 0.0 2.8 2 0 0 2 2 2 2 Fibronectin type III domain V-set PF07686.17 KFQ96856.1 - 1.2e-17 64.0 1.3 0.00097 19.3 0.0 7.1 6 4 2 8 8 8 3 Immunoglobulin V-set domain Ig_6 PF18452.1 KFQ96856.1 - 2.9e-07 29.9 0.0 7.9 6.1 0.0 5.4 5 0 0 5 5 5 2 Immunoglobulin domain C2-set_2 PF08205.12 KFQ96856.1 - 4.9e-06 26.5 0.4 0.34 11.0 0.0 3.6 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFQ96856.1 - 0.0014 18.6 0.0 10 6.3 0.0 4.5 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain C2-set PF05790.15 KFQ96856.1 - 0.064 13.4 0.1 2.2 8.5 0.0 3.2 3 0 0 3 3 3 0 Immunoglobulin C2-set domain V-set_CD47 PF08204.11 KFQ96856.1 - 0.13 12.3 0.0 6.9 6.7 0.0 3.2 4 0 0 4 4 4 0 CD47 immunoglobulin-like domain CH PF00307.31 KFQ96857.1 - 6.4e-21 74.6 0.0 8.2e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 KFQ96857.1 - 1e-13 50.6 6.2 1e-13 50.6 6.2 1.9 2 0 0 2 2 2 1 Calponin family repeat CDC24 PF06395.11 KFQ96857.1 - 0.01 16.1 0.0 0.015 15.6 0.0 1.2 1 0 0 1 1 1 0 CDC24 Calponin TPH PF13868.6 KFQ96858.1 - 1e-78 264.4 173.0 1e-78 264.4 173.0 2.0 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain IQ PF00612.27 KFQ96859.1 - 0.064 13.1 0.2 0.073 12.9 0.2 1.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif zf-C4 PF00105.18 KFQ96860.1 - 2.6e-30 104.7 14.3 4.3e-30 104.0 14.3 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFQ96860.1 - 1.1e-20 74.1 2.4 2.7e-20 72.8 2.4 1.5 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Porin_3 PF01459.22 KFQ96861.1 - 7.9e-32 110.8 0.4 8.7e-32 110.6 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin UCH PF00443.29 KFQ96862.1 - 2.6e-32 112.3 0.0 3e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFQ96862.1 - 3.5e-12 46.6 0.1 2.8e-10 40.3 0.0 2.0 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Glyco_transf_7N PF13733.6 KFQ96863.1 - 2.6e-56 188.9 0.0 3.3e-56 188.6 0.0 1.1 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 KFQ96863.1 - 1.1e-31 108.3 0.0 1.9e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Pex19 PF04614.12 KFQ96865.1 - 7.6e-43 147.0 0.4 9.5e-43 146.7 0.4 1.0 1 0 0 1 1 1 1 Pex19 protein family GlutR_dimer PF00745.20 KFQ96865.1 - 0.046 14.2 1.1 0.96 9.9 0.0 2.9 1 1 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain HIP1_clath_bdg PF16515.5 KFQ96865.1 - 0.069 13.8 4.5 0.15 12.6 4.5 1.5 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 XPC-binding PF09280.11 KFQ96865.1 - 0.3 10.8 2.9 0.65 9.8 0.2 2.9 4 0 0 4 4 4 0 XPC-binding domain DUF3450 PF11932.8 KFQ96865.1 - 0.95 8.7 4.9 1.5 8.1 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) SDA1 PF05285.12 KFQ96866.1 - 0.039 13.4 17.1 0.047 13.1 17.1 1.1 1 0 0 1 1 1 0 SDA1 Lin-8 PF03353.15 KFQ96866.1 - 0.15 11.6 6.9 0.2 11.2 6.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 KFQ96866.1 - 1.2 7.8 8.5 1.5 7.5 8.5 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 KFQ96866.1 - 3.6 5.8 16.7 4.5 5.5 16.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KFQ96866.1 - 4.6 5.3 21.3 5.7 5.0 21.3 1.0 1 0 0 1 1 1 0 Nop14-like family eIF-3c_N PF05470.12 KFQ96866.1 - 5.1 5.3 10.5 6.8 4.9 10.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DED PF01335.21 KFQ96867.1 - 4.7e-20 71.7 0.2 6.6e-20 71.2 0.2 1.2 1 0 0 1 1 1 1 Death effector domain FCD PF07729.12 KFQ96867.1 - 0.04 14.3 0.4 0.12 12.8 0.4 1.7 1 1 0 1 1 1 0 FCD domain FWWh PF14922.6 KFQ96867.1 - 0.11 12.4 0.1 0.16 11.9 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function IRK_C PF17655.1 KFQ96869.1 - 9.8e-67 223.9 0.0 1.4e-66 223.4 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFQ96869.1 - 5.9e-56 188.2 0.5 9.8e-56 187.5 0.5 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 KFQ96869.1 - 0.023 14.6 3.6 0.053 13.5 3.6 1.7 1 1 0 1 1 1 0 Ion channel DUF2182 PF09948.9 KFQ96869.1 - 0.042 13.7 0.5 0.076 12.9 0.5 1.3 1 0 0 1 1 1 0 Predicted metal-binding integral membrane protein (DUF2182) HLH PF00010.26 KFQ96870.1 - 4e-10 39.5 0.6 6.3e-10 38.9 0.6 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain VWD PF00094.25 KFQ96872.1 - 6.7e-43 146.7 0.0 4.8e-31 108.2 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type D domain C8 PF08742.11 KFQ96872.1 - 8.6e-40 135.0 11.5 2.3e-21 76.0 2.5 4.8 5 0 0 5 5 5 2 C8 domain TIL PF01826.17 KFQ96872.1 - 4.9e-21 74.7 34.9 4.9e-12 45.9 12.9 6.2 7 0 0 7 7 7 2 Trypsin Inhibitor like cysteine rich domain TILa PF12714.7 KFQ96872.1 - 9.5e-09 35.1 10.8 9.5e-09 35.1 10.8 4.8 3 1 2 5 5 4 1 TILa domain VWD PF00094.25 KFQ96873.1 - 1.3e-32 113.3 0.3 1.5e-32 113.1 0.3 1.0 1 0 0 1 1 1 1 von Willebrand factor type D domain VWD PF00094.25 KFQ96874.1 - 4e-47 160.4 3.5 8.1e-33 113.9 0.1 2.4 2 0 0 2 2 2 2 von Willebrand factor type D domain C8 PF08742.11 KFQ96874.1 - 2.7e-39 133.4 10.6 2.3e-22 79.2 1.8 4.7 6 0 0 6 6 6 2 C8 domain TIL PF01826.17 KFQ96874.1 - 2e-18 66.3 43.5 2e-12 47.2 17.6 5.3 5 0 0 5 5 5 2 Trypsin Inhibitor like cysteine rich domain TILa PF12714.7 KFQ96874.1 - 6.1e-07 29.3 3.9 6.1e-07 29.3 3.9 5.9 5 1 2 7 7 7 1 TILa domain C8 PF08742.11 KFQ96875.1 - 1.3e-37 128.0 15.8 8.9e-23 80.5 3.7 3.7 4 1 1 5 5 5 2 C8 domain VWD PF00094.25 KFQ96875.1 - 6.9e-30 104.4 0.0 4e-18 66.2 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type D domain TIL PF01826.17 KFQ96875.1 - 2e-12 47.1 14.4 2e-12 47.1 14.4 5.3 5 1 0 5 5 5 1 Trypsin Inhibitor like cysteine rich domain TILa PF12714.7 KFQ96875.1 - 7.1e-11 41.9 9.4 7.1e-11 41.9 9.4 3.8 3 1 1 4 4 4 1 TILa domain LRR_6 PF13516.6 KFQ96876.1 - 0.00011 22.0 0.0 0.0097 15.9 0.0 2.3 2 0 0 2 2 2 2 Leucine Rich repeat Ephrin PF00812.17 KFQ96877.1 - 1.4e-32 112.5 0.1 1.8e-32 112.2 0.1 1.1 1 0 0 1 1 1 1 Ephrin Cnd2 PF05786.14 KFQ96881.1 - 1.2e-15 57.3 0.0 1.2e-15 57.3 0.0 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 7tm_4 PF13853.6 KFQ96882.1 - 4.1e-24 85.8 1.0 4.5e-24 85.6 1.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ96882.1 - 0.00036 19.9 3.2 0.00048 19.5 3.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Yae1_N PF09811.9 KFQ96883.1 - 1.2e-11 44.1 37.2 3.9e+03 -2.4 37.2 4.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Keratin PF02422.16 KFQ96885.1 - 5.9e-40 134.9 10.2 6.3e-40 134.8 10.2 1.0 1 0 0 1 1 1 1 Keratin CALCOCO1 PF07888.11 KFQ96885.1 - 0.29 9.9 0.1 0.31 9.8 0.1 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Keratin PF02422.16 KFQ96886.1 - 3.2e-36 122.9 11.2 3.4e-36 122.8 11.2 1.0 1 0 0 1 1 1 1 Keratin CALCOCO1 PF07888.11 KFQ96886.1 - 0.079 11.8 0.2 0.081 11.8 0.2 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3522 PF12036.8 KFQ96888.1 - 4.4e-09 36.9 4.2 7.3e-09 36.2 4.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) Plasmod_Pvs28 PF06247.11 KFQ96888.1 - 0.74 10.2 5.6 1.9 8.8 5.6 1.6 1 0 0 1 1 1 0 Pvs28 EGF domain EGF_2 PF07974.13 KFQ96888.1 - 5.1 7.6 8.5 16 5.9 8.5 1.9 1 0 0 1 1 1 0 EGF-like domain Ribosomal_S4e PF00900.20 KFQ96891.1 - 7.3e-40 134.7 0.5 1.2e-39 134.0 0.5 1.4 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 KFQ96891.1 - 2.8e-08 33.3 0.5 5.3e-08 32.4 0.5 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 KFQ96891.1 - 2.6e-06 27.0 0.0 5.1e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KFQ96891.1 - 5.5e-06 26.2 1.2 1.5e-05 24.8 0.2 2.4 2 0 0 2 2 2 1 KOW motif RS4NT PF08071.12 KFQ96891.1 - 0.009 16.1 0.8 0.021 14.9 0.8 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain Sipho_tail PF05709.11 KFQ96891.1 - 0.11 11.8 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Phage tail protein TGF_beta PF00019.20 KFQ96892.1 - 3.9e-28 98.5 0.0 5.9e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain DUF3732 PF12532.8 KFQ96893.1 - 0.032 13.8 0.0 0.042 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3732) ASD2 PF08687.11 KFQ96894.1 - 2.9e-56 191.2 7.1 3.2e-56 191.0 7.1 1.0 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 Amido_AtzD_TrzD PF09663.10 KFQ96894.1 - 0.017 14.1 0.1 0.02 13.9 0.1 1.0 1 0 0 1 1 1 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) TetR_C_34 PF17929.1 KFQ96894.1 - 0.063 13.4 0.2 0.41 10.8 0.1 1.9 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DAGK_acc PF00609.19 KFQ96895.1 - 6.2e-51 172.9 0.0 1.2e-50 172.0 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KFQ96895.1 - 1.5e-26 92.4 0.0 1.8e-25 89.0 0.0 2.7 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 KFQ96895.1 - 4.8e-15 55.2 24.5 5.1e-09 35.9 5.1 3.3 3 0 0 3 3 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 KFQ96895.1 - 5.6e-15 55.7 0.5 1.1e-14 54.7 0.5 1.6 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.17 KFQ96895.1 - 1.7e-07 31.3 0.0 3.7e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFQ96895.1 - 6.2e-07 29.8 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_8 PF15409.6 KFQ96895.1 - 6.6e-05 23.1 0.2 0.00017 21.8 0.2 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain C1_2 PF03107.16 KFQ96895.1 - 0.00032 20.9 14.4 0.0049 17.2 4.3 2.8 2 0 0 2 2 2 2 C1 domain PH_11 PF15413.6 KFQ96895.1 - 0.0014 19.0 4.0 0.01 16.2 1.8 3.4 2 1 0 2 2 2 1 Pleckstrin homology domain Mcp5_PH PF12814.7 KFQ96895.1 - 0.08 13.1 1.3 0.12 12.5 0.1 1.9 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology DUF4456 PF14644.6 KFQ96895.1 - 0.085 12.5 0.2 0.085 12.5 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4456) DUF5320 PF17253.2 KFQ96895.1 - 2.5 9.2 4.4 36 5.5 0.1 3.9 3 0 0 3 3 3 0 Family of unknown function (DUF5320) Cyclin_N PF00134.23 KFQ96896.1 - 3.2e-07 30.2 0.0 4.9e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Gal_Lectin PF02140.18 KFQ96897.1 - 1.4e-37 127.9 5.4 5.7e-19 68.3 0.7 2.3 2 0 0 2 2 2 2 Galactose binding lectin domain FAM176 PF14851.6 KFQ96897.1 - 3.6e-12 46.2 0.0 5.5e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 FAM176 family DUF3395 PF11875.8 KFQ96897.1 - 0.018 14.9 0.0 2.6 7.9 0.0 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF3395) GST_C_2 PF13410.6 KFQ96898.1 - 5.8e-07 29.4 0.0 1.1e-06 28.6 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFQ96898.1 - 7.8e-07 29.3 0.0 3.4e-06 27.3 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFQ96898.1 - 0.00033 21.0 0.0 0.00077 19.8 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 KFQ96898.1 - 0.0028 17.9 0.0 0.014 15.6 0.0 2.1 1 1 0 1 1 1 1 Glutaredoxin GST_C PF00043.25 KFQ96898.1 - 0.025 14.8 0.0 0.056 13.7 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF1533 PF07550.11 KFQ96898.1 - 0.061 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1533) Amidase PF01425.21 KFQ96900.1 - 5.5e-79 266.2 0.0 1.4e-78 264.8 0.0 1.7 1 1 0 1 1 1 1 Amidase TSC22 PF01166.18 KFQ96901.1 - 4.4e-28 97.4 4.9 4.4e-28 97.4 4.9 1.9 2 0 0 2 2 2 1 TSC-22/dip/bun family YabA PF06156.13 KFQ96901.1 - 0.00067 20.3 2.6 0.00067 20.3 2.6 1.7 2 0 0 2 2 2 1 Initiation control protein YabA DivIC PF04977.15 KFQ96901.1 - 0.0021 17.8 3.5 0.0081 15.9 2.2 2.2 2 0 0 2 2 2 1 Septum formation initiator ZapB PF06005.12 KFQ96901.1 - 0.0073 16.7 4.5 0.0073 16.7 4.5 1.7 2 0 0 2 2 2 1 Cell division protein ZapB TBK1_CCD1 PF18394.1 KFQ96901.1 - 0.0088 15.6 2.8 0.055 13.0 1.2 2.0 1 1 1 2 2 2 1 TANK-binding kinase 1 coiled-coil domain 1 K-box PF01486.17 KFQ96901.1 - 0.015 15.5 1.9 0.015 15.5 1.9 1.9 2 0 0 2 2 2 0 K-box region bZIP_2 PF07716.15 KFQ96901.1 - 0.16 12.1 5.4 0.37 10.9 5.4 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Fzo_mitofusin PF04799.13 KFQ96901.1 - 0.28 10.7 3.5 0.089 12.3 0.9 1.4 2 0 0 2 2 2 0 fzo-like conserved region COS PF18568.1 KFQ96902.1 - 2.5e-34 117.0 0.8 2.1e-33 114.0 1.1 2.3 2 0 0 2 2 2 1 TRIM C-terminal subgroup One Signature domain SPRY PF00622.28 KFQ96902.1 - 8.3e-13 48.5 0.0 1.5e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 SPRY domain zf-B_box PF00643.24 KFQ96902.1 - 5.8e-09 36.0 1.0 5.8e-09 36.0 1.0 4.5 6 0 0 6 6 5 2 B-box zinc finger PRY PF13765.6 KFQ96902.1 - 2.9e-07 30.0 0.0 9.6e-07 28.3 0.0 2.0 1 0 0 1 1 1 1 SPRY-associated domain zf-RING_UBOX PF13445.6 KFQ96902.1 - 3.7e-07 30.1 9.4 3.7e-07 30.1 9.4 3.5 3 0 0 3 3 3 1 RING-type zinc-finger fn3 PF00041.21 KFQ96902.1 - 6.3e-07 29.7 0.2 1.3e-06 28.7 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III domain zf-C3HC4_3 PF13920.6 KFQ96902.1 - 8.5e-07 28.7 6.4 8.5e-07 28.7 6.4 3.9 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ96902.1 - 3e-06 27.0 10.8 3e-06 27.0 10.8 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFQ96902.1 - 3.4e-06 27.1 13.1 3.4e-06 27.1 13.1 4.1 5 0 0 5 5 4 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KFQ96902.1 - 3.7e-06 26.7 5.5 3.7e-06 26.7 5.5 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ96902.1 - 2.8e-05 24.4 10.9 2.8e-05 24.4 10.9 3.5 4 0 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 KFQ96902.1 - 0.00067 19.6 8.6 0.00067 19.6 8.6 3.6 4 0 0 4 4 4 1 zinc-RING finger domain CEBP_ZZ PF16366.5 KFQ96902.1 - 0.022 15.0 2.9 0.022 15.0 2.9 3.0 3 0 0 3 3 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Pur_ac_phosph_N PF16656.5 KFQ96902.1 - 0.036 14.6 0.1 0.088 13.4 0.1 1.7 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Med22 PF06179.12 KFQ96902.1 - 0.14 12.4 7.5 0.37 11.0 7.5 1.8 1 0 0 1 1 1 0 Surfeit locus protein 5 subunit 22 of Mediator complex DNA_topoisoIV PF00521.20 KFQ96902.1 - 0.38 9.6 7.0 0.58 9.0 7.0 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Wax2_C PF12076.8 KFQ96902.1 - 0.93 9.2 7.9 4.3 7.0 0.2 2.5 2 0 0 2 2 2 0 WAX2 C-terminal domain Dict-STAT-coil PF09267.10 KFQ96902.1 - 2.1 8.7 11.4 0.19 12.1 6.0 2.0 2 0 0 2 2 2 0 Dictyostelium STAT, coiled coil NHS PF15273.6 KFQ96903.1 - 7.1e-31 108.0 27.0 7.3e-27 94.8 19.3 3.2 4 0 0 4 4 4 2 NHS-like Rotamase_3 PF13616.6 KFQ96904.1 - 5.4e-19 68.9 0.1 2.3e-18 66.8 0.1 1.9 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 KFQ96904.1 - 3.1e-16 60.1 0.0 5.4e-16 59.3 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KFQ96904.1 - 0.0055 17.5 0.0 0.0081 17.0 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain SNF2_N PF00176.23 KFQ96905.1 - 8.2e-51 172.8 0.4 1.1e-48 165.8 0.1 2.4 2 1 1 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KFQ96905.1 - 7.1e-21 74.6 0.2 1.6e-19 70.3 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFQ96905.1 - 6.6e-14 52.3 0.0 3.1e-13 50.1 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 KFQ96905.1 - 1.2e-05 24.3 0.0 1.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 SWI2_SNF2 PF18766.1 KFQ96905.1 - 6.9e-05 22.6 0.1 0.00027 20.7 0.0 1.9 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DEAD PF00270.29 KFQ96905.1 - 0.00029 20.6 0.0 0.00092 19.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KFQ96905.1 - 0.00066 18.9 0.0 0.0014 17.9 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD_2 PF06733.15 KFQ96905.1 - 0.019 14.6 0.1 0.052 13.2 0.1 1.7 1 0 0 1 1 1 0 DEAD_2 DUF2075 PF09848.9 KFQ96905.1 - 0.15 11.3 0.1 2.9 7.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) OCRL_clath_bd PF16726.5 KFQ96906.1 - 4e-33 113.7 0.4 1e-32 112.4 0.4 1.8 1 0 0 1 1 1 1 Inositol polyphosphate 5-phosphatase clathrin binding domain RhoGAP PF00620.27 KFQ96906.1 - 1.2e-24 86.8 0.2 2.2e-24 86.0 0.2 1.4 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 KFQ96906.1 - 1.5e-15 57.4 0.0 2.5e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Minor_capsid_3 PF12691.7 KFQ96906.1 - 0.0017 18.8 0.6 1.4 9.3 0.1 2.8 3 0 0 3 3 3 2 Minor capsid protein from bacteriophage VGLL4 PF15245.6 KFQ96906.1 - 0.12 12.4 0.2 0.26 11.4 0.2 1.5 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 Creatinase_N_2 PF16189.5 KFQ96907.1 - 3.9e-44 150.6 0.0 5.1e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KFQ96908.1 - 4.3e-33 114.8 0.0 5.5e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KFQ96908.1 - 2.3e-21 75.6 0.1 3.4e-21 75.1 0.1 1.3 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 SLY PF12485.8 KFQ96909.1 - 5.5e-20 72.7 4.7 1e-19 71.8 4.7 1.5 1 0 0 1 1 1 1 Lymphocyte signaling adaptor protein SAM_2 PF07647.17 KFQ96909.1 - 2.7e-09 37.0 0.6 4e-09 36.5 0.6 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFQ96909.1 - 8.6e-09 35.7 0.2 1.3e-08 35.1 0.2 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 KFQ96909.1 - 2.9e-06 26.9 0.0 5.2e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFQ96909.1 - 0.0049 16.4 0.0 0.0087 15.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Herpes_LMP2 PF07415.11 KFQ96909.1 - 0.097 11.4 0.6 0.14 10.9 0.6 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein DHHC PF01529.20 KFQ96910.1 - 2e-35 121.8 12.6 2e-35 121.8 12.6 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase Utp14 PF04615.13 KFQ96911.1 - 1.5e-153 513.2 48.1 1.3e-82 278.6 39.8 2.0 1 1 1 2 2 2 2 Utp14 protein RhoGAP PF00620.27 KFQ96913.1 - 5.4e-51 172.4 0.1 1.3e-50 171.2 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain RhoGAP-FF1 PF16512.5 KFQ96913.1 - 6.6e-29 100.4 15.1 4.8e-28 97.6 6.7 3.7 3 0 0 3 3 3 1 p190-A and -B Rho GAPs FF domain Ras PF00071.22 KFQ96913.1 - 4e-12 46.0 0.5 3.1e-06 26.9 0.1 4.2 4 0 0 4 4 4 2 Ras family FF PF01846.19 KFQ96913.1 - 1.2e-07 31.8 7.8 6.2e-07 29.5 1.2 3.4 3 0 0 3 3 3 1 FF domain GTP_EFTU PF00009.27 KFQ96913.1 - 0.0062 16.1 0.5 0.053 13.0 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain NOG1 PF06858.14 KFQ96913.1 - 0.022 14.5 0.1 0.069 12.9 0.1 1.9 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) Cdh1_DBD_1 PF18196.1 KFQ96913.1 - 0.051 13.9 1.2 0.17 12.2 1.2 1.9 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 Trypsin PF00089.26 KFQ96915.1 - 1.4e-69 234.3 0.6 1.6e-69 234.1 0.6 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFQ96915.1 - 1.8e-05 25.1 0.1 4e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 KFQ96915.1 - 0.00026 21.9 0.0 0.0004 21.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KFQ96917.1 - 7.6e-74 248.2 2.0 8.5e-74 248.1 2.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFQ96917.1 - 3.5e-05 24.7 0.0 5.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFQ96917.1 - 0.0006 20.2 0.6 0.0018 18.6 0.6 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) zf-CCHC_3 PF13917.6 KFQ96919.1 - 0.018 15.0 0.0 0.019 15.0 0.0 1.3 1 1 0 1 1 1 0 Zinc knuckle CDI PF02234.19 KFQ96922.1 - 2.2e-21 75.8 6.9 4.6e-21 74.7 3.0 2.5 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor CDI PF02234.19 KFQ96923.1 - 1.1e-18 67.2 0.7 1.3e-18 66.9 0.7 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor Coat_F PF07875.12 KFQ96923.1 - 0.015 15.5 0.1 0.021 15.0 0.1 1.2 1 0 0 1 1 1 0 Coat F domain 7tm_1 PF00001.21 KFQ96924.1 - 2.4e-43 148.4 15.7 2.9e-43 148.1 15.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ96924.1 - 1e-08 34.9 14.9 1.4e-08 34.5 14.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFQ96924.1 - 0.0003 20.6 12.5 0.026 14.3 12.5 2.5 1 1 0 1 1 1 1 Olfactory receptor DUF5083 PF16890.5 KFQ96924.1 - 0.14 11.8 8.4 0.28 10.9 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5083) DUF1761 PF08570.10 KFQ96924.1 - 0.35 11.1 11.1 1.8 8.8 1.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1761) DUF4271 PF14093.6 KFQ96924.1 - 4.3 7.2 19.8 0.053 13.4 7.7 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4271) bZIP_2 PF07716.15 KFQ96925.1 - 1.6e-08 34.5 7.8 2.5e-08 33.8 7.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KFQ96925.1 - 7.3e-05 22.8 6.9 0.00012 22.1 6.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor DSPc PF00782.20 KFQ96926.1 - 9.5e-44 148.4 0.0 1.7e-43 147.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 KFQ96926.1 - 3.5e-16 59.7 0.0 1.5e-15 57.6 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.27 KFQ96926.1 - 0.00012 21.7 0.1 0.00039 20.1 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase zf-RING_14 PF17978.1 KFQ96926.1 - 0.0056 17.1 0.3 0.18 12.2 0.0 2.5 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Init_tRNA_PT PF04179.12 KFQ96926.1 - 0.056 13.7 0.5 0.66 10.3 0.0 2.4 2 0 0 2 2 2 0 Rit1 DUSP-like domain LOH1CR12 PF10158.9 KFQ96927.1 - 9.7e-57 190.6 1.8 1.2e-56 190.3 1.8 1.1 1 0 0 1 1 1 1 Tumour suppressor protein DUF1664 PF07889.12 KFQ96927.1 - 0.0024 17.9 1.4 0.0036 17.3 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) RE_Bpu10I PF09549.10 KFQ96927.1 - 0.0053 16.4 0.2 0.0071 16.0 0.2 1.2 1 0 0 1 1 1 1 Bpu10I restriction endonuclease BLOC1_2 PF10046.9 KFQ96927.1 - 0.029 14.7 0.7 0.056 13.7 0.7 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 POX PF07526.11 KFQ96927.1 - 0.45 11.1 4.2 0.65 10.6 4.2 1.5 1 1 0 1 1 1 0 Associated with HOX MANEC PF07502.14 KFQ96928.1 - 1.8e-17 63.4 0.7 3e-17 62.7 0.7 1.3 1 0 0 1 1 1 1 MANEC domain DUF5585 PF17823.1 KFQ96928.1 - 7.9e-07 28.4 0.2 7.9e-07 28.4 0.2 2.4 1 1 1 2 2 2 1 Family of unknown function (DUF5585) Ldl_recept_b PF00058.17 KFQ96929.1 - 1.7e-156 508.5 43.4 3.3e-13 49.9 0.1 20.4 20 0 0 20 20 20 20 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 KFQ96929.1 - 2.1e-40 136.7 64.6 1.9e-11 44.1 8.2 5.7 5 1 0 5 5 5 4 Coagulation Factor Xa inhibitory site Ldl_recept_a PF00057.18 KFQ96929.1 - 2.2e-31 107.8 47.8 6.1e-11 42.4 8.3 3.8 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A DUF5050 PF16472.5 KFQ96929.1 - 5.2e-20 71.8 0.0 0.00014 21.2 0.0 6.6 4 3 2 7 7 7 5 Domain of unknown function (DUF5050) SGL PF08450.12 KFQ96929.1 - 2.8e-16 59.9 18.5 0.12 12.0 0.0 11.9 6 4 4 12 12 12 5 SMP-30/Gluconolactonase/LRE-like region cEGF PF12662.7 KFQ96929.1 - 0.0017 18.3 0.6 0.0017 18.3 0.6 5.2 5 0 0 5 5 5 2 Complement Clr-like EGF-like EGF PF00008.27 KFQ96929.1 - 0.0097 16.2 4.9 0.0097 16.2 4.9 6.2 6 0 0 6 6 6 4 EGF-like domain YoeB_toxin PF06769.14 KFQ96929.1 - 0.24 11.4 2.8 44 4.2 0.1 4.3 4 0 0 4 4 4 0 YoeB-like toxin of bacterial type II toxin-antitoxin system Bcl-2 PF00452.19 KFQ96930.1 - 5.6e-05 23.8 0.0 0.00015 22.4 0.0 1.8 1 1 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family CF222 PF15661.5 KFQ96930.1 - 0.00022 20.3 2.2 0.00029 19.9 2.2 1.2 1 0 0 1 1 1 1 C6orf222, uncharacterised family BID PF06393.11 KFQ96930.1 - 0.034 13.7 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 BH3 interacting domain (BID) RPAP3_C PF13877.6 KFQ96930.1 - 0.096 13.2 0.1 0.2 12.2 0.1 1.6 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 Ets PF00178.22 KFQ96931.1 - 2.4e-30 104.8 1.5 5.3e-30 103.7 1.5 1.6 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 KFQ96931.1 - 7.5e-27 93.1 0.0 1.3e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_3 PF18016.1 KFQ96931.1 - 0.00062 19.5 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFQ96931.1 - 0.13 12.8 0.6 0.38 11.2 0.6 1.8 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) TPR_14 PF13428.6 KFQ96932.1 - 8.3e-05 23.1 0.2 6 8.0 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFQ96932.1 - 0.0016 17.9 5.2 0.0056 16.1 0.4 3.1 2 1 2 4 4 4 1 MalT-like TPR region TPR_2 PF07719.17 KFQ96932.1 - 0.0025 17.8 7.7 4 7.8 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFQ96932.1 - 0.0034 17.9 0.2 4 8.3 0.0 4.7 6 0 0 6 6 6 1 Tetratricopeptide repeat PKD_channel PF08016.12 KFQ96933.1 - 3.4e-112 375.2 10.4 6.8e-112 374.3 7.2 2.2 2 0 0 2 2 2 1 Polycystin cation channel REJ PF02010.15 KFQ96933.1 - 5.4e-92 308.9 1.1 7.8e-92 308.4 0.2 1.6 2 0 0 2 2 2 1 REJ domain PLAT PF01477.23 KFQ96933.1 - 3.6e-21 75.9 0.0 1.2e-20 74.2 0.0 2.0 1 0 0 1 1 1 1 PLAT/LH2 domain Ion_trans PF00520.31 KFQ96933.1 - 3.5e-08 33.0 20.9 3.5e-08 33.0 20.9 2.9 4 0 0 4 4 4 1 Ion transport protein GPS PF01825.21 KFQ96933.1 - 0.27 11.8 2.5 0.82 10.2 2.5 1.9 1 0 0 1 1 1 0 GPCR proteolysis site, GPS, motif C6_DPF PF10170.9 KFQ96934.1 - 1e-40 138.0 3.6 1.3e-40 137.7 3.6 1.1 1 0 0 1 1 1 1 Cysteine-rich domain zf-C4 PF00105.18 KFQ96935.1 - 1.4e-28 99.2 15.9 2.6e-28 98.3 15.9 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFQ96935.1 - 5.5e-16 58.8 0.2 1.2e-15 57.7 0.2 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-BED PF02892.15 KFQ96935.1 - 9.4 6.4 12.9 19 5.4 0.0 3.3 3 0 0 3 3 3 0 BED zinc finger wnt PF00110.19 KFQ96937.1 - 9.4e-125 416.3 26.3 1.1e-124 416.1 26.3 1.0 1 0 0 1 1 1 1 wnt family Atx10homo_assoc PF09759.9 KFQ96938.1 - 1.6e-40 137.1 10.3 1.1e-38 131.2 0.9 4.2 4 1 1 5 5 5 2 Spinocerebellar ataxia type 10 protein domain DUF484 PF04340.12 KFQ96938.1 - 0.02 14.6 0.4 0.02 14.6 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF484 Coatamer_beta_C PF07718.12 KFQ96938.1 - 0.11 12.4 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 Coatomer beta C-terminal region EGF_CA PF07645.15 KFQ96939.1 - 1.9e-69 229.6 138.1 3.1e-11 43.3 5.1 10.8 11 0 0 11 11 11 9 Calcium-binding EGF domain cEGF PF12662.7 KFQ96939.1 - 6.1e-59 195.5 65.4 2.3e-09 37.0 2.0 9.9 8 0 0 8 8 8 8 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFQ96939.1 - 1.1e-26 92.8 136.1 1.7e-06 28.2 9.1 11.3 11 1 0 11 11 11 7 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 KFQ96939.1 - 1.1e-10 41.5 121.5 0.00017 21.7 6.1 10.8 10 1 0 10 10 10 9 EGF domain ANATO PF01821.18 KFQ96939.1 - 4.8e-05 24.1 19.0 0.00035 21.4 6.3 9.5 9 2 1 10 10 10 2 Anaphylotoxin-like domain EGF PF00008.27 KFQ96939.1 - 0.00025 21.3 122.3 0.0052 17.0 8.3 11.6 10 0 0 10 10 10 7 EGF-like domain hEGF PF12661.7 KFQ96939.1 - 0.011 16.3 6.7 0.011 16.3 6.7 13.1 12 1 0 12 12 12 0 Human growth factor-like EGF GBP_PSP PF02425.15 KFQ96939.1 - 4 7.2 15.4 0.48 10.1 1.4 4.4 4 0 0 4 4 4 0 Paralytic/GBP/PSP peptide RIB43A PF05914.12 KFQ96940.1 - 7.4e-128 426.5 59.0 8.3e-128 426.3 59.0 1.0 1 0 0 1 1 1 1 RIB43A SIR2_2 PF13289.6 KFQ96941.1 - 9.1e-18 64.8 0.0 1.8e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 SIR2-like domain STI1 PF17830.1 KFQ96941.1 - 0.034 14.1 0.2 3.8 7.5 0.0 2.6 2 0 0 2 2 2 0 STI1 domain DUF2045 PF09741.9 KFQ96942.1 - 1.1e-96 322.7 1.3 1.4e-96 322.4 1.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2045) NUP50 PF08911.11 KFQ96943.1 - 1.2e-21 77.2 0.8 1.2e-21 77.2 0.8 3.0 4 0 0 4 4 4 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 KFQ96943.1 - 1.3e-10 41.6 0.0 2.4e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain PHD PF00628.29 KFQ96944.1 - 7.9e-08 32.1 6.8 1.5e-07 31.1 6.8 1.5 1 0 0 1 1 1 1 PHD-finger Zf_RING PF16744.5 KFQ96944.1 - 0.71 10.0 7.0 3.7 7.7 7.0 2.2 1 1 0 1 1 1 0 KIAA1045 RING finger zf-rbx1 PF12678.7 KFQ96944.1 - 0.95 9.8 7.2 2.4 8.5 7.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain CRAL_TRIO_2 PF13716.6 KFQ96945.1 - 4e-38 130.7 3.5 8.6e-38 129.6 3.5 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 KFQ96945.1 - 1e-37 129.3 0.0 2.8e-37 127.9 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain CRAL_TRIO PF00650.20 KFQ96945.1 - 1.1e-12 48.0 0.5 2.3e-12 46.9 0.5 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain YvbH_ext PF11724.8 KFQ96945.1 - 0.98 9.8 4.6 2.7 8.4 0.6 2.5 1 1 1 2 2 2 0 YvbH-like oligomerisation region HbrB PF08539.11 KFQ96946.1 - 7.3e-16 58.6 0.6 2.7e-14 53.5 0.1 2.3 1 1 1 2 2 2 2 HbrB-like Shisa PF13908.6 KFQ96947.1 - 3.6e-07 30.6 5.7 3.6e-07 30.6 5.7 2.1 2 0 0 2 2 2 2 Wnt and FGF inhibitory regulator CH PF00307.31 KFQ96948.1 - 9.5e-25 86.9 3.7 3.1e-14 53.1 1.6 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFQ96948.1 - 5.6e-06 26.1 0.2 0.031 14.1 0.0 2.5 2 0 0 2 2 2 2 CAMSAP CH domain CH PF00307.31 KFQ96949.1 - 3.8e-28 97.8 2.0 9.9e-18 64.3 1.2 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFQ96949.1 - 0.0012 18.6 0.0 0.91 9.4 0.0 2.6 2 0 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.11 KFQ96949.1 - 0.0015 18.6 0.2 1.1 9.4 0.0 2.3 2 0 0 2 2 2 2 CH-like domain in sperm protein ACT PF01842.25 KFQ96949.1 - 0.098 12.5 0.0 0.36 10.7 0.0 2.0 1 0 0 1 1 1 0 ACT domain Bac_surface_Ag PF01103.23 KFQ96950.1 - 1.8e-63 215.0 2.6 2.1e-63 214.8 2.6 1.0 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 KFQ96950.1 - 0.0028 18.2 0.0 0.0046 17.5 0.0 1.4 1 0 0 1 1 1 1 Surface antigen variable number repeat Patatin PF01734.22 KFQ96951.1 - 1.8e-06 28.3 0.0 3.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Sulfotransfer_1 PF00685.27 KFQ96952.1 - 9.9e-50 169.5 0.2 1.4e-49 169.0 0.2 1.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFQ96952.1 - 7.7e-09 36.2 0.1 1.1e-08 35.7 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase family Peptidase_C92 PF05708.12 KFQ96952.1 - 0.0067 16.5 0.0 0.0096 16.0 0.0 1.3 1 0 0 1 1 1 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family DUF758 PF05527.11 KFQ96952.1 - 0.042 13.8 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF758) Sulfotransfer_4 PF17784.1 KFQ96952.1 - 0.055 13.3 0.2 0.15 11.9 0.2 1.5 1 1 0 1 1 1 0 Sulfotransferase domain NPA PF16469.5 KFQ96952.1 - 0.063 13.9 0.1 0.16 12.6 0.1 1.6 1 1 0 1 1 1 0 Nematode polyprotein allergen ABA-1 FdsD PF11390.8 KFQ96952.1 - 0.19 12.1 1.4 2.6 8.4 1.5 2.3 1 1 1 2 2 2 0 NADH-dependant formate dehydrogenase delta subunit FdsD Adeno_E1A PF02703.14 KFQ96953.1 - 0.053 13.1 0.4 0.074 12.6 0.4 1.2 1 0 0 1 1 1 0 Early E1A protein Metallophos PF00149.28 KFQ96954.1 - 2.1e-11 44.7 0.6 3.2e-11 44.1 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFQ96954.1 - 2.1e-07 31.3 0.0 4.9e-06 26.8 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FXa_inhibition PF14670.6 KFQ96956.1 - 9e-66 217.8 172.3 1.3e-12 47.7 9.1 12.0 12 0 0 12 12 12 9 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFQ96956.1 - 1.2e-45 153.0 85.8 2.1e-09 37.2 1.1 12.3 11 1 0 11 11 11 9 Complement Clr-like EGF-like Ephrin_rec_like PF07699.13 KFQ96956.1 - 1.4e-35 120.8 34.9 4.2e-15 55.2 8.4 6.7 7 1 1 8 8 8 3 Putative ephrin-receptor like EGF_CA PF07645.15 KFQ96956.1 - 1.5e-29 101.9 170.9 2.7e-09 37.1 8.5 11.9 12 0 0 12 12 12 7 Calcium-binding EGF domain EGF_3 PF12947.7 KFQ96956.1 - 5.6e-22 77.6 139.9 2.7e-10 40.3 9.5 11.2 10 1 0 10 10 10 8 EGF domain CUB PF00431.20 KFQ96956.1 - 4.3e-17 62.5 0.0 4.3e-17 62.5 0.0 2.5 3 0 0 3 3 3 1 CUB domain EGF PF00008.27 KFQ96956.1 - 4.7e-16 58.8 136.7 8.9e-06 25.9 5.4 12.1 10 1 2 12 12 12 8 EGF-like domain hEGF PF12661.7 KFQ96956.1 - 9.8e-05 22.8 12.6 0.00015 22.2 1.9 12.5 11 1 0 11 11 11 6 Human growth factor-like EGF DUF4375 PF14300.6 KFQ96956.1 - 0.15 12.3 0.2 20 5.5 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4375) DUF5398 PF17376.2 KFQ96956.1 - 0.17 12.5 0.5 0.46 11.1 0.5 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5398) TTL PF03133.15 KFQ96958.1 - 1.7e-72 244.1 0.1 2.4e-72 243.6 0.1 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family YkuI_C PF10388.9 KFQ96958.1 - 0.092 12.6 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain TspO_MBR PF03073.15 KFQ96959.1 - 1.5e-49 167.5 13.4 1.8e-49 167.3 13.4 1.0 1 0 0 1 1 1 1 TspO/MBR family DUF1358 PF07096.11 KFQ96959.1 - 2.6 8.1 6.0 0.64 10.0 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1358) Acyl_transf_1 PF00698.21 KFQ96960.1 - 8.8e-05 22.2 0.0 9.4e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Acyl transferase domain bcl-2I13 PF12201.8 KFQ96961.1 - 1.6e-07 31.4 0.0 2.2e-07 30.9 0.0 1.3 1 1 0 1 1 1 1 Bcl2-interacting killer, BH3-domain containing Bclx_interact PF08945.10 KFQ96961.1 - 0.013 15.3 0.0 0.038 13.8 0.0 1.8 2 0 0 2 2 2 0 Bcl-x interacting, BH3 domain BMF PF15185.6 KFQ96961.1 - 0.17 11.6 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis TTL PF03133.15 KFQ96962.1 - 6.2e-114 380.1 0.7 8.3e-114 379.7 0.7 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KFQ96962.1 - 6.5e-08 32.1 0.0 0.00028 20.2 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KFQ96962.1 - 2.4e-05 23.7 0.0 0.00088 18.6 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp FCH PF00611.23 KFQ96963.1 - 9.1e-16 57.9 0.3 9.1e-16 57.9 0.3 3.2 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KFQ96963.1 - 1.8e-15 56.3 0.1 3.9e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFQ96963.1 - 1.9e-15 56.4 0.2 4.1e-15 55.4 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFQ96963.1 - 3.3e-08 33.1 0.0 6.1e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain NPF PF16601.5 KFQ96963.1 - 1e-05 26.1 8.3 1e-05 26.1 8.3 1.8 2 0 0 2 2 2 1 Rabosyn-5 repeating NPF sequence-motif SH3_10 PF17902.1 KFQ96963.1 - 0.13 12.3 0.0 0.54 10.4 0.0 2.0 2 0 0 2 2 2 0 SH3 domain LIN52 PF10044.9 KFQ96963.1 - 0.22 12.3 2.6 0.82 10.4 0.8 2.6 2 0 0 2 2 2 0 Retinal tissue protein DegS PF05384.11 KFQ96963.1 - 6.1 6.3 18.3 0.078 12.5 8.0 2.8 3 1 0 3 3 3 0 Sensor protein DegS ArfGap PF01412.18 KFQ96964.1 - 1e-27 96.5 8.3 1.4e-27 96.1 1.4 2.7 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf Gb3_synth PF04572.12 KFQ96965.1 - 3.6e-48 163.0 2.3 5.3e-48 162.5 2.3 1.3 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.15 KFQ96965.1 - 3.1e-22 79.0 0.0 1e-21 77.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KFQ96965.1 - 0.048 13.0 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain HEPN-like_int PF18867.1 KFQ96965.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 HEPN-like integron domain Gb3_synth PF04572.12 KFQ96966.1 - 8e-45 152.2 3.0 1.3e-44 151.5 3.0 1.3 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.15 KFQ96966.1 - 4.7e-22 78.5 0.0 1.9e-21 76.5 0.0 2.0 3 0 0 3 3 3 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KFQ96966.1 - 0.21 10.8 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Gb3_synth PF04572.12 KFQ96967.1 - 8.2e-45 152.2 3.0 1.3e-44 151.5 3.0 1.3 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.15 KFQ96967.1 - 2.1e-22 79.6 0.0 8.6e-22 77.6 0.0 2.0 3 0 0 3 3 3 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KFQ96967.1 - 0.054 12.8 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain XendoU PF09412.10 KFQ96968.1 - 2.7e-103 344.8 0.1 3e-103 344.6 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU EndoU_bacteria PF14436.6 KFQ96968.1 - 0.0037 17.6 0.0 0.031 14.6 0.0 2.1 2 0 0 2 2 2 1 Bacterial EndoU nuclease Sybindin PF04099.12 KFQ96968.1 - 0.11 12.4 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Sybindin-like family FAD_binding_6 PF00970.24 KFQ96969.1 - 7e-37 125.8 0.0 1e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KFQ96969.1 - 9.1e-36 122.8 0.0 1.4e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KFQ96969.1 - 6.6e-06 26.3 0.0 0.00029 21.0 0.0 2.2 1 1 0 2 2 2 1 Ferric reductase NAD binding domain Rab15_effector PF15208.6 KFQ96970.1 - 5.7e-127 421.9 0.6 6.4e-127 421.8 0.6 1.0 1 0 0 1 1 1 1 Rab15 effector SAM_1 PF00536.30 KFQ96971.1 - 5.6e-39 132.4 9.4 6.2e-17 61.8 0.7 4.1 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFQ96971.1 - 2.3e-33 114.1 7.5 2.4e-14 53.2 0.0 4.2 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) DUF16 PF01519.16 KFQ96971.1 - 0.00091 19.7 2.1 0.00091 19.7 2.1 3.0 2 0 0 2 2 2 1 Protein of unknown function DUF16 SAM_PNT PF02198.16 KFQ96971.1 - 0.0014 18.5 3.2 0.21 11.6 0.2 3.4 3 0 0 3 3 3 2 Sterile alpha motif (SAM)/Pointed domain DUF4407 PF14362.6 KFQ96971.1 - 0.26 10.6 13.8 3.1 7.1 11.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) LRS4 PF10422.9 KFQ96971.1 - 0.69 9.4 16.9 1 8.9 11.2 2.9 3 1 0 3 3 3 0 Monopolin complex subunit LRS4 Prismane PF03063.20 KFQ96971.1 - 0.74 8.4 2.4 7.2 5.2 2.9 1.9 2 0 0 2 2 2 0 Prismane/CO dehydrogenase family ADIP PF11559.8 KFQ96971.1 - 5.2 7.1 23.8 8.1 6.5 9.5 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding PAS_11 PF14598.6 KFQ96972.1 - 1.4e-27 96.0 0.2 9.9e-24 83.6 0.1 2.3 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 KFQ96972.1 - 3.1e-24 85.1 0.0 4.2e-16 59.0 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 KFQ96972.1 - 1.5e-23 82.9 0.0 8.9e-11 41.8 0.0 2.3 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 KFQ96972.1 - 8.8e-16 57.6 2.4 2.7e-15 56.1 2.4 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 KFQ96972.1 - 9e-14 51.6 0.0 6.3e-07 29.6 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KFQ96972.1 - 3.7e-07 30.4 0.0 0.0031 17.7 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.11 KFQ96972.1 - 0.0045 17.6 0.0 0.02 15.6 0.0 1.9 2 0 0 2 2 2 1 PAS fold Pam17 PF08566.10 KFQ96972.1 - 0.055 13.3 0.0 0.34 10.7 0.0 2.3 3 0 0 3 3 3 0 Mitochondrial import protein Pam17 Bro-N PF02498.17 KFQ96972.1 - 0.09 13.5 0.0 0.86 10.3 0.0 2.4 2 0 0 2 2 2 0 BRO family, N-terminal domain Pkinase PF00069.25 KFQ96973.1 - 5.7e-61 206.2 0.1 2.4e-60 204.1 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ96973.1 - 1.4e-27 96.6 2.2 3.9e-19 69.0 0.3 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KFQ96973.1 - 7.1e-08 33.0 1.6 1.3e-07 32.2 0.9 1.8 2 0 0 2 2 2 1 Protein kinase C terminal domain Kdo PF06293.14 KFQ96973.1 - 0.00057 19.3 0.2 0.0011 18.4 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFQ96973.1 - 0.001 18.1 0.1 0.0015 17.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFQ96973.1 - 0.0015 18.5 0.9 0.21 11.5 0.2 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KFQ96973.1 - 0.0023 17.3 0.4 0.074 12.4 0.1 2.5 2 1 0 2 2 2 1 Kinase-like Med21 PF11221.8 KFQ96976.1 - 2.4e-29 102.4 1.1 3.6e-29 101.9 1.1 1.3 1 0 0 1 1 1 1 Subunit 21 of Mediator complex TelA PF05816.11 KFQ96976.1 - 0.0023 17.1 0.1 0.0031 16.6 0.1 1.2 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) DUF4203 PF13886.6 KFQ96977.1 - 9.1e-41 139.7 36.4 1.3e-40 139.3 36.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) SIKE PF05769.11 KFQ96978.1 - 1.1e-72 243.8 26.3 1.3e-72 243.5 26.3 1.0 1 0 0 1 1 1 1 SIKE family Tho2 PF11262.8 KFQ96978.1 - 0.001 18.4 5.8 0.001 18.4 5.8 1.6 1 1 1 2 2 2 1 Transcription factor/nuclear export subunit protein 2 FIN1 PF17300.2 KFQ96978.1 - 0.087 12.3 8.8 0.18 11.3 8.8 1.5 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 TPR_8 PF13181.6 KFQ96978.1 - 0.21 11.9 1.1 10 6.6 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat CotJB PF12652.7 KFQ96978.1 - 0.28 11.4 1.7 4.2 7.7 0.1 2.6 2 0 0 2 2 2 0 CotJB protein CHD5 PF04420.14 KFQ96978.1 - 0.43 10.4 4.6 1.3 8.8 4.6 1.8 1 1 0 1 1 1 0 CHD5-like protein DUF3829 PF12889.7 KFQ96978.1 - 0.83 9.1 12.6 0.067 12.7 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) BST2 PF16716.5 KFQ96978.1 - 3.2 8.4 19.2 2.9 8.5 2.4 3.6 3 1 1 4 4 4 0 Bone marrow stromal antigen 2 LapA_dom PF06305.11 KFQ96978.1 - 3.4 7.5 4.9 1.7 8.5 0.8 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Exonuc_VII_L PF02601.15 KFQ96978.1 - 3.5 7.1 13.1 4.9 6.6 13.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit bZIP_1 PF00170.21 KFQ96978.1 - 3.5 7.8 21.7 3.6 7.8 0.6 4.4 2 2 1 4 4 4 0 bZIP transcription factor FUSC PF04632.12 KFQ96978.1 - 3.7 6.0 11.3 4.3 5.7 11.0 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family DASH_Dam1 PF08653.10 KFQ96978.1 - 4.1 7.3 5.0 1.5 8.7 0.2 2.6 3 0 0 3 3 3 0 DASH complex subunit Dam1 NYD-SP28_assoc PF14775.6 KFQ96978.1 - 4.3 7.5 13.6 0.98 9.6 1.9 3.6 3 1 0 3 3 3 0 Sperm tail C-terminal domain Mgr1 PF08602.10 KFQ96978.1 - 4.4 6.0 9.9 2.6 6.8 7.2 1.8 1 1 1 2 2 2 0 Mgr1-like, i-AAA protease complex subunit Sec20 PF03908.13 KFQ96978.1 - 8.6 6.4 13.3 8.7 6.3 0.4 3.4 1 1 3 4 4 4 0 Sec20 DUF2151 PF10221.9 KFQ96979.1 - 1.3e-302 1005.6 4.4 1.5e-302 1005.4 4.4 1.0 1 0 0 1 1 1 1 Cell cycle and development regulator Plk4_PB2 PF18409.1 KFQ96979.1 - 0.065 13.9 0.1 0.63 10.8 0.1 2.6 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 a_DG1_N2 PF18424.1 KFQ96980.1 - 1.1e-05 25.5 0.0 2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Alpha-Dystroglycan N-terminal domain 2 CD20 PF04103.15 KFQ96982.1 - 7.3e-25 87.9 15.1 9.9e-25 87.5 15.1 1.2 1 0 0 1 1 1 1 CD20-like family TcpE PF12648.7 KFQ96982.1 - 0.017 15.6 2.4 0.017 15.6 2.4 2.1 2 0 0 2 2 2 0 TcpE family DUF2371 PF10177.9 KFQ96982.1 - 0.48 10.6 3.8 8.2 6.6 0.2 3.1 1 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) DUF5336 PF17270.2 KFQ96982.1 - 1.6 8.4 8.1 2.1 7.9 5.6 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5336) RA PF00788.23 KFQ96983.1 - 3.6e-08 33.9 0.0 8.6e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain DUF5344 PF17279.2 KFQ96983.1 - 0.02 15.4 5.9 0.02 15.4 5.9 3.7 2 1 0 4 4 4 0 Family of unknown function (DUF5344) Tropomyosin PF00261.20 KFQ96983.1 - 0.033 13.6 41.9 0.049 13.0 27.5 2.2 1 1 1 2 2 2 0 Tropomyosin Fib_alpha PF08702.10 KFQ96983.1 - 0.074 13.2 31.7 0.39 10.9 4.7 4.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family YscO PF07321.12 KFQ96983.1 - 3.9 7.4 41.0 3.6 7.5 5.7 2.5 1 1 1 2 2 2 0 Type III secretion protein YscO HrpB7 PF09486.10 KFQ96983.1 - 6.5 7.1 21.9 1.5e+02 2.7 1.3 3.6 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Ras PF00071.22 KFQ96984.1 - 1.3e-58 197.2 0.0 1.5e-58 196.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ96984.1 - 6.5e-22 78.0 0.0 1.3e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ96984.1 - 9.5e-10 38.2 0.0 1.2e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFQ96984.1 - 2.4e-07 30.5 0.5 2.3e-06 27.3 0.1 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFQ96984.1 - 2.5e-06 27.5 0.0 0.017 15.1 0.0 2.5 2 1 1 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 KFQ96984.1 - 1.2e-05 25.4 0.1 3e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase MeaB PF03308.16 KFQ96984.1 - 0.0015 17.6 0.2 0.022 13.7 0.1 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB G-alpha PF00503.20 KFQ96984.1 - 0.0023 17.2 0.3 0.091 11.9 0.3 2.1 1 1 1 2 2 2 2 G-protein alpha subunit FeoB_N PF02421.18 KFQ96984.1 - 0.0024 17.4 0.0 0.022 14.3 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 KFQ96984.1 - 0.019 14.8 0.7 0.4 10.4 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.18 KFQ96984.1 - 0.024 13.9 0.3 0.054 12.8 0.0 1.9 2 1 0 2 2 2 0 Septin AAA_25 PF13481.6 KFQ96984.1 - 0.15 11.6 0.0 0.38 10.3 0.0 1.7 2 1 1 3 3 3 0 AAA domain Complex1_LYR PF05347.15 KFQ96985.1 - 1.9e-15 56.7 0.1 2.9e-15 56.1 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFQ96985.1 - 5.9e-08 33.3 0.6 7.9e-08 32.9 0.6 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Casc1_N PF15927.5 KFQ96986.1 - 7.4e-60 202.1 17.1 7.4e-60 202.1 17.1 2.9 3 0 0 3 3 3 1 Cancer susceptibility candidate 1 N-terminus MRVI1 PF05781.12 KFQ96987.1 - 6.1e-146 487.2 11.0 6.8e-146 487.1 11.0 1.0 1 0 0 1 1 1 1 MRVI1 protein KorB PF08535.10 KFQ96987.1 - 0.027 14.5 0.2 0.067 13.2 0.2 1.7 1 0 0 1 1 1 0 KorB domain YejG PF13989.6 KFQ96987.1 - 0.036 14.5 0.2 0.13 12.7 0.3 1.9 2 0 0 2 2 2 0 YejG-like protein DUF919 PF06034.11 KFQ96987.1 - 0.74 9.7 5.6 0.34 10.8 1.9 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF1117 PF06547.12 KFQ96987.1 - 0.76 10.3 3.7 0.69 10.5 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) IZUMO PF15005.6 KFQ96987.1 - 0.95 10.0 5.5 1.9 9.0 5.5 1.4 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated Fib_alpha PF08702.10 KFQ96987.1 - 1.8 8.8 7.4 3.7 7.7 7.4 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Spexin PF15171.6 KFQ96989.1 - 4.7e-41 138.9 2.0 4.7e-41 138.9 2.0 1.5 2 0 0 2 2 2 1 Neuropeptide secretory protein family, NPQ, spexin Glycogen_syn PF05693.13 KFQ96990.1 - 0 1186.0 0.0 0 1185.7 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 KFQ96990.1 - 2.3e-05 24.0 0.0 0.00037 20.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFQ96990.1 - 4.5e-05 23.9 0.0 0.0062 17.0 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFQ96990.1 - 4.6e-05 23.5 0.1 9.3e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Ldh_1_N PF00056.23 KFQ96991.1 - 4.8e-41 140.2 0.1 7.2e-41 139.6 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KFQ96991.1 - 1.1e-21 77.5 0.0 1.6e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 KFQ96991.1 - 0.00017 21.2 0.0 0.00033 20.2 0.0 1.5 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase IRK_C PF17655.1 KFQ96992.1 - 2.2e-71 239.0 0.0 3.1e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFQ96992.1 - 4.6e-59 198.3 3.5 6.8e-59 197.7 3.5 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain EI24 PF07264.11 KFQ96992.1 - 0.097 12.9 3.2 0.15 12.3 3.2 1.3 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DOR PF14839.6 KFQ96992.1 - 0.12 12.3 1.2 0.19 11.7 1.2 1.2 1 0 0 1 1 1 0 DOR family ABC_membrane PF00664.23 KFQ96993.1 - 1.1e-65 222.0 25.4 2.6e-33 115.9 3.7 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFQ96993.1 - 4e-52 176.4 0.2 1.3e-24 87.3 0.0 3.4 4 0 0 4 4 3 2 ABC transporter SMC_N PF02463.19 KFQ96993.1 - 2.7e-07 30.2 7.2 0.018 14.5 0.1 4.3 3 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFQ96993.1 - 8.6e-06 25.8 2.3 0.95 9.2 0.0 3.7 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFQ96993.1 - 2.4e-05 24.3 0.1 0.023 14.6 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KFQ96993.1 - 0.00016 21.4 1.5 0.078 12.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KFQ96993.1 - 0.0014 18.7 0.1 1.6 8.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase IstB_IS21 PF01695.17 KFQ96993.1 - 0.0025 17.6 0.1 5.3 6.7 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_22 PF13401.6 KFQ96993.1 - 0.004 17.4 0.1 2.1 8.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 KFQ96993.1 - 0.012 14.9 0.0 0.2 10.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 KFQ96993.1 - 0.013 15.1 0.0 3.4 7.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 KFQ96993.1 - 0.022 15.2 0.1 0.62 10.4 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 KFQ96993.1 - 0.031 13.9 0.0 0.93 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KFQ96993.1 - 0.044 12.9 0.0 4.8 6.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_ATPase PF09818.9 KFQ96993.1 - 0.047 12.5 0.9 7.3 5.3 0.0 3.3 3 1 0 3 3 3 0 Predicted ATPase of the ABC class AAA_24 PF13479.6 KFQ96993.1 - 0.069 12.9 0.1 1.2 8.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KFQ96993.1 - 0.072 12.8 0.0 2.6 7.7 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 KFQ96993.1 - 0.3 10.4 1.2 9.9 5.4 0.1 2.3 2 0 0 2 2 2 0 KaiC Dynamin_N PF00350.23 KFQ96993.1 - 0.53 10.3 2.7 1.8 8.6 0.1 2.7 2 0 0 2 2 2 0 Dynamin family AAA_23 PF13476.6 KFQ96993.1 - 0.54 10.7 12.9 15 6.0 0.0 3.2 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KFQ96993.1 - 0.57 9.8 3.6 3.2 7.3 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain CTP_transf_3 PF02348.19 KFQ96994.1 - 6.2e-35 121.1 0.0 8.7e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase Hydrolase_3 PF08282.12 KFQ96994.1 - 9.1e-06 25.6 0.2 0.00014 21.7 0.0 2.7 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Sulfotransfer_1 PF00685.27 KFQ96995.1 - 1.8e-66 224.4 4.0 1.4e-61 208.4 2.1 2.1 1 1 1 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFQ96995.1 - 0.00077 19.9 0.0 0.0099 16.3 0.0 2.1 2 0 0 2 2 2 1 Sulfotransferase family zf-C2H2_3 PF13878.6 KFQ96995.1 - 0.16 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO Glyco_transf_29 PF00777.18 KFQ96996.1 - 6.9e-78 261.7 0.0 8.1e-78 261.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Gag_p30 PF02093.16 KFQ96997.1 - 3.8e-22 78.8 0.1 4.4e-22 78.6 0.1 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein Gag_p24 PF00607.20 KFQ96997.1 - 0.0027 17.6 0.1 0.0037 17.1 0.1 1.2 1 0 0 1 1 1 1 gag gene protein p24 (core nucleocapsid protein) C2 PF00168.30 KFQ96998.1 - 3.7e-15 56.1 0.0 7.2e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain YbjQ_1 PF01906.17 KFQ96998.1 - 7.9e-05 23.2 4.1 0.027 15.1 0.0 4.7 4 1 0 4 4 4 1 Putative heavy-metal-binding Choline_kinase PF01633.20 KFQ96999.1 - 1.8e-62 210.7 0.1 2.5e-62 210.2 0.1 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KFQ96999.1 - 7.1e-14 52.3 0.0 1e-13 51.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFQ96999.1 - 0.00015 21.2 0.6 0.00021 20.7 0.1 1.5 2 0 0 2 2 2 1 Ecdysteroid kinase HMG_box PF00505.19 KFQ97001.1 - 2.6e-22 79.0 3.8 2.6e-22 79.0 3.8 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFQ97001.1 - 5.9e-09 36.4 1.1 5.9e-09 36.4 1.1 3.4 4 0 0 4 4 4 1 HMG-box domain MPS2 PF17060.5 KFQ97001.1 - 0.016 14.5 6.5 0.033 13.5 6.5 1.4 1 0 0 1 1 1 0 Monopolar spindle protein 2 Spc7 PF08317.11 KFQ97001.1 - 0.24 10.3 19.3 0.18 10.7 11.2 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein LOH1CR12 PF10158.9 KFQ97001.1 - 0.33 11.0 0.1 0.33 11.0 0.1 2.4 2 0 0 2 2 2 0 Tumour suppressor protein Cob_adeno_trans PF01923.18 KFQ97001.1 - 3.8 7.6 7.0 1.8 8.7 3.5 2.0 2 0 0 2 2 2 0 Cobalamin adenosyltransferase HemX PF04375.14 KFQ97001.1 - 4.1 6.6 24.0 0.25 10.6 16.6 2.1 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase AAA_23 PF13476.6 KFQ97001.1 - 4.7 7.7 16.7 35 4.8 14.5 2.5 2 0 0 2 2 2 0 AAA domain SOAR PF16533.5 KFQ97001.1 - 4.8 7.2 15.2 1.3 9.0 0.4 2.6 2 0 0 2 2 2 0 STIM1 Orai1-activating region UPF0242 PF06785.11 KFQ97001.1 - 6.8 6.7 19.8 3.5 7.7 15.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DivIVA PF05103.13 KFQ97001.1 - 9.6 6.3 20.0 3.6 7.7 14.8 2.3 2 0 0 2 2 2 0 DivIVA protein Aminotran_4 PF01063.19 KFQ97003.1 - 4.2e-34 118.4 0.0 5e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Got1 PF04178.12 KFQ97005.1 - 1e-17 64.6 16.1 1.2e-17 64.3 16.1 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Ac81 PF05820.11 KFQ97005.1 - 0.18 11.4 0.1 0.28 10.8 0.1 1.3 1 0 0 1 1 1 0 Baculoviridae AC81 Fzo_mitofusin PF04799.13 KFQ97005.1 - 0.27 10.8 0.0 0.37 10.3 0.0 1.1 1 0 0 1 1 1 0 fzo-like conserved region DUF3185 PF11381.8 KFQ97005.1 - 2.5 8.2 15.6 0.29 11.2 0.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) Helicase_C PF00271.31 KFQ97006.1 - 7.2e-18 65.0 0.1 5.4e-16 58.9 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFQ97006.1 - 7.5e-17 61.6 0.0 1.6e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KFQ97006.1 - 4.4e-13 49.8 5.4 1.8e-12 47.8 5.4 2.1 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 KFQ97006.1 - 0.00014 21.9 0.0 0.00058 19.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RQC PF09382.10 KFQ97006.1 - 0.00021 21.0 0.0 0.0035 17.1 0.0 2.7 1 1 0 1 1 1 1 RQC domain KOW PF00467.29 KFQ97006.1 - 0.058 13.4 0.2 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 KOW motif NinF PF05810.12 KFQ97006.1 - 0.07 13.0 0.1 0.07 13.0 0.1 2.1 2 0 0 2 2 2 0 NinF protein Osmo_CC PF08946.10 KFQ97006.1 - 2.4 8.4 4.9 6.8 7.0 4.9 1.8 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Pyr_redox_2 PF07992.14 KFQ97007.1 - 5.1e-23 81.7 0.0 3.9e-11 42.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 KFQ97007.1 - 1e-07 31.7 0.5 6.9e-07 29.1 0.0 2.3 2 0 0 2 2 2 1 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox_3 PF13738.6 KFQ97007.1 - 0.01 15.1 0.5 0.54 9.5 0.0 3.1 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase P_proprotein PF01483.20 KFQ97009.1 - 8.3e-31 105.9 0.1 1.3e-30 105.2 0.1 1.3 1 0 0 1 1 1 1 Proprotein convertase P-domain GF_recep_IV PF14843.6 KFQ97009.1 - 1.8e-15 56.9 89.4 7.4e-11 42.0 39.1 3.4 1 1 2 3 3 3 3 Growth factor receptor domain IV PLAC PF08686.11 KFQ97009.1 - 9.5e-13 48.7 6.3 9.5e-13 48.7 6.3 5.0 7 0 0 7 7 7 1 PLAC (protease and lacunin) domain Furin-like_2 PF15913.5 KFQ97009.1 - 8e-12 45.3 73.4 1.2e-05 25.4 19.2 4.8 1 1 2 3 3 3 3 Furin-like repeat, cysteine-rich VSP PF03302.13 KFQ97009.1 - 3.8e-08 32.6 63.7 9.2e-08 31.3 39.8 5.7 2 1 4 6 6 6 3 Giardia variant-specific surface protein CDC37_M PF08565.11 KFQ97011.1 - 6.6e-20 71.2 1.9 1.1e-19 70.5 0.0 2.1 2 1 0 2 2 2 1 Cdc37 Hsp90 binding domain Ribosomal_L2_C PF03947.18 KFQ97012.1 - 7.9e-49 165.1 3.0 1.1e-48 164.6 3.0 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KFQ97012.1 - 3e-08 33.5 0.0 1.2e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain UCH PF00443.29 KFQ97013.1 - 5.4e-50 170.3 0.5 3.3e-49 167.7 0.1 2.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFQ97013.1 - 3.1e-27 96.0 0.0 9.1e-26 91.2 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1722 PF08349.11 KFQ97013.1 - 0.057 13.7 0.0 15 5.9 0.0 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) FAST_1 PF06743.15 KFQ97013.1 - 0.11 12.5 0.2 1.3 9.0 0.0 2.9 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 Vps23_core PF09454.10 KFQ97013.1 - 0.17 11.9 0.6 1.1 9.3 0.1 2.8 3 0 0 3 3 3 0 Vps23 core domain Cas9_a PF18470.1 KFQ97013.1 - 0.18 11.3 0.7 0.46 10.0 0.6 1.7 1 1 0 1 1 1 0 Cas9 alpha-helical lobe domain Med14 PF08638.11 KFQ97014.1 - 9.7e-52 175.2 0.0 2.5e-51 173.8 0.0 1.7 1 0 0 1 1 1 1 Mediator complex subunit MED14 RE_SinI PF09570.10 KFQ97014.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 SinI restriction endonuclease Renin_r PF07850.14 KFQ97015.1 - 4.7e-37 126.5 1.2 7.2e-37 125.9 1.2 1.3 1 0 0 1 1 1 1 Renin receptor-like protein Glycophorin_A PF01102.18 KFQ97015.1 - 0.075 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A DUF2273 PF10031.9 KFQ97015.1 - 0.095 12.7 1.0 0.16 12.0 1.0 1.4 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) PSP94 PF05825.11 KFQ97017.1 - 4.3e-08 33.6 5.6 5.7e-08 33.2 5.6 1.1 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) VWC PF00093.18 KFQ97017.1 - 0.0034 17.7 4.3 0.0072 16.6 4.3 1.7 1 1 0 1 1 1 1 von Willebrand factor type C domain TILa PF12714.7 KFQ97017.1 - 0.077 13.0 7.2 0.15 12.0 7.3 1.7 1 1 0 1 1 1 0 TILa domain Rgp1 PF08737.10 KFQ97018.1 - 6.4e-34 117.8 0.6 8.2e-25 87.8 0.0 2.5 2 1 1 3 3 3 2 Rgp1 DUF4512 PF14975.6 KFQ97020.1 - 1.9e-17 63.8 2.0 2e-17 63.7 2.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4512) Ribosomal_L22 PF00237.19 KFQ97021.1 - 4.1e-49 165.1 0.1 6.2e-49 164.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Thyroglobulin_1 PF00086.18 KFQ97025.1 - 3.3e-19 68.3 3.3 6.2e-19 67.4 3.3 1.5 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat NUFIP2 PF15293.6 KFQ97028.1 - 0 1010.9 24.1 0 1010.7 24.1 1.0 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 2 Crystall PF00030.19 KFQ97029.1 - 6.4e-60 199.3 6.3 6.6e-30 103.1 0.3 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.13 KFQ97029.1 - 0.0021 17.9 0.7 0.94 9.5 0.0 2.8 2 0 0 2 2 2 2 Peptidase inhibitor family I36 IL4_i_Ig PF18258.1 KFQ97029.1 - 0.004 17.3 5.4 29 4.9 0.0 4.1 1 1 3 4 4 4 3 Interleukin-4 inducing immunoglobulin-binding domain DAO PF01266.24 KFQ97030.1 - 5.4e-40 138.0 0.2 6.2e-40 137.9 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFQ97030.1 - 0.00028 21.0 0.0 0.00061 20.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KFQ97030.1 - 0.0089 14.8 0.0 0.04 12.6 0.0 1.9 2 1 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KFQ97030.1 - 0.016 14.3 0.1 0.053 12.6 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KFQ97030.1 - 0.019 14.0 0.0 0.033 13.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KFQ97030.1 - 0.042 13.1 0.0 0.55 9.4 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KFQ97030.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 KFQ97030.1 - 0.25 10.6 0.0 0.41 9.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Sushi PF00084.20 KFQ97032.1 - 4.4e-37 126.5 17.4 1.3e-10 41.7 3.1 4.3 4 0 0 4 4 4 4 Sushi repeat (SCR repeat) CUB PF00431.20 KFQ97032.1 - 8.6e-16 58.2 0.0 9.8e-15 54.9 0.0 2.3 2 0 0 2 2 2 1 CUB domain SKG6 PF08693.10 KFQ97032.1 - 0.033 13.6 1.2 0.061 12.7 1.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain cEGF PF12662.7 KFQ97032.1 - 0.065 13.2 11.0 1.4 8.9 0.1 4.1 3 1 0 3 3 3 0 Complement Clr-like EGF-like Band_7 PF01145.25 KFQ97034.1 - 1.7e-19 70.5 0.1 1.7e-19 70.5 0.1 2.8 2 1 0 2 2 2 1 SPFH domain / Band 7 family Flot PF15975.5 KFQ97034.1 - 5.1e-10 39.6 9.5 5.1e-10 39.6 9.5 3.4 1 1 1 3 3 3 2 Flotillin YjbH PF06082.11 KFQ97034.1 - 0.15 10.9 5.8 0.2 10.5 5.8 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH FAM222A PF15258.6 KFQ97035.1 - 1.5e-281 935.1 38.5 1.7e-281 934.9 38.5 1.0 1 0 0 1 1 1 1 Protein family of FAM222A MATH PF00917.26 KFQ97036.1 - 3.2e-05 24.0 0.0 0.022 14.9 0.0 2.0 1 1 1 2 2 2 2 MATH domain TRAM_LAG1_CLN8 PF03798.16 KFQ97037.1 - 6.6e-16 58.6 12.0 7.9e-16 58.4 12.0 1.1 1 0 0 1 1 1 1 TLC domain DUF4223 PF13978.6 KFQ97037.1 - 0.091 12.7 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) Ribosomal_L23eN PF03939.13 KFQ97038.1 - 7.1e-23 80.6 11.4 7.1e-23 80.6 11.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KFQ97038.1 - 2.1e-16 60.1 3.1 2.1e-16 60.1 3.1 2.6 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L6 PF00347.23 KFQ97038.1 - 0.046 14.4 1.8 0.052 14.2 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein L6 Ras PF00071.22 KFQ97039.1 - 9e-46 155.4 0.1 1.1e-45 155.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ97039.1 - 7.3e-31 106.9 0.0 1.1e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ97039.1 - 2.7e-16 59.5 0.0 3.6e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFQ97039.1 - 2.8e-07 30.6 0.0 5.2e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFQ97039.1 - 4.2e-05 23.0 0.0 5.1e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFQ97039.1 - 0.00038 19.9 0.0 0.00053 19.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KFQ97039.1 - 0.0033 17.0 0.1 0.29 10.7 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 KFQ97039.1 - 0.009 16.1 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 KFQ97039.1 - 0.0093 16.0 0.0 0.78 9.8 0.0 2.7 2 1 1 3 3 3 1 Dynamin family TniB PF05621.11 KFQ97039.1 - 0.029 13.8 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 KFQ97039.1 - 0.069 13.1 0.0 12 5.8 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase DUF695 PF05117.12 KFQ97039.1 - 0.079 13.1 0.0 0.13 12.4 0.0 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF695) TsaE PF02367.17 KFQ97039.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 KFQ97039.1 - 0.16 11.3 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 KFQ97039.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SH2_2 PF14633.6 KFQ97040.1 - 1.7e-84 282.5 0.2 1.7e-84 282.5 0.2 2.2 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.6 KFQ97040.1 - 2e-71 238.6 0.0 6.5e-71 237.0 0.0 2.0 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 KFQ97040.1 - 2e-50 169.5 0.1 4.7e-50 168.3 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.6 KFQ97040.1 - 5.8e-26 91.2 2.4 1.8e-25 89.6 2.4 1.8 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 KFQ97040.1 - 2.5e-15 56.8 31.6 2.5e-15 56.8 31.6 8.0 7 1 2 9 9 7 2 Acidic N-terminal SPT6 Tex_N PF09371.10 KFQ97040.1 - 2.4e-08 33.9 0.0 0.008 15.9 0.0 3.1 2 1 0 2 2 2 2 Tex-like protein N-terminal domain HHH_3 PF12836.7 KFQ97040.1 - 1.3e-07 31.8 0.0 4.6e-07 30.0 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif S1 PF00575.23 KFQ97040.1 - 2e-06 28.0 0.1 5.7e-06 26.6 0.1 1.8 1 0 0 1 1 1 1 S1 RNA binding domain SH2 PF00017.24 KFQ97040.1 - 4e-06 26.8 0.0 1.2e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 SH2 domain HHH_9 PF17674.1 KFQ97040.1 - 1.1e-05 26.3 0.1 7.7e-05 23.5 0.1 2.7 1 0 0 1 1 1 1 HHH domain Tex_YqgF PF16921.5 KFQ97040.1 - 0.00025 21.5 0.0 0.00054 20.4 0.0 1.5 1 0 0 1 1 1 1 Tex protein YqgF-like domain zf-Sec23_Sec24 PF04810.15 KFQ97040.1 - 0.16 12.1 0.2 0.47 10.6 0.2 1.7 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Pkinase PF00069.25 KFQ97042.1 - 1.8e-38 132.4 0.0 1.9e-38 132.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ97042.1 - 4.2e-19 68.8 0.0 4.8e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ97042.1 - 5e-07 29.3 0.1 1.5e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFQ97042.1 - 0.0012 17.8 0.1 0.0012 17.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KFQ97042.1 - 0.002 17.0 0.0 0.0026 16.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFQ97042.1 - 0.0025 17.2 0.3 0.0031 16.9 0.3 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFQ97042.1 - 0.0049 16.8 0.3 0.0059 16.5 0.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFQ97042.1 - 0.035 13.2 0.0 0.1 11.6 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 TPR_MLP1_2 PF07926.12 KFQ97043.1 - 0.0097 16.0 3.5 0.01 15.9 3.5 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein MukF_M PF17192.4 KFQ97043.1 - 0.022 14.5 3.1 0.032 14.0 3.1 1.3 1 1 0 1 1 1 0 MukF middle domain DUF2783 PF10932.8 KFQ97043.1 - 0.048 13.4 0.4 0.087 12.5 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2783) YabA PF06156.13 KFQ97043.1 - 0.05 14.2 0.9 0.053 14.1 0.9 1.2 1 0 0 1 1 1 0 Initiation control protein YabA BLOC1S3 PF15753.5 KFQ97043.1 - 0.054 13.6 0.9 0.21 11.7 0.9 1.8 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 PI3K_P85_iSH2 PF16454.5 KFQ97043.1 - 0.063 12.9 5.1 0.41 10.2 4.9 1.9 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Wtap PF17098.5 KFQ97043.1 - 0.14 12.1 4.9 0.19 11.7 4.9 1.3 1 0 0 1 1 1 0 WTAP/Mum2p family OmpH PF03938.14 KFQ97043.1 - 0.17 12.2 2.0 0.2 12.0 2.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FapA PF03961.13 KFQ97043.1 - 0.31 9.6 0.7 0.3 9.6 0.7 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Ribosomal_L29 PF00831.23 KFQ97043.1 - 1.1 9.3 5.7 1.8 8.6 2.6 2.6 2 1 1 3 3 3 0 Ribosomal L29 protein Glycolytic PF00274.19 KFQ97045.1 - 3.7e-182 604.8 0.0 4.1e-182 604.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I PIG-S PF10510.9 KFQ97046.1 - 2.1e-122 409.6 0.0 2.3e-122 409.4 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein GMP_PDE_delta PF05351.11 KFQ97047.1 - 4.6e-79 264.0 3.1 5.2e-79 263.8 3.1 1.0 1 0 0 1 1 1 1 GMP-PDE, delta subunit IIGP PF05049.13 KFQ97047.1 - 0.11 11.5 0.2 0.15 11.1 0.2 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Forkhead PF00250.18 KFQ97048.1 - 1.3e-34 118.3 1.4 1.6e-34 118.0 0.2 1.9 2 0 0 2 2 2 1 Forkhead domain Na_sulph_symp PF00939.19 KFQ97049.1 - 7.3e-149 496.8 24.2 8.3e-149 496.6 24.2 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KFQ97049.1 - 1e-32 113.5 30.7 6.8e-20 71.5 1.6 3.1 2 1 1 3 3 3 2 Citrate transporter DUF4834 PF16118.5 KFQ97049.1 - 1.3 10.1 4.8 31 5.6 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) MFS_1 PF07690.16 KFQ97050.1 - 5.9e-14 51.7 26.8 5.9e-14 51.7 26.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily SAM_2 PF07647.17 KFQ97051.1 - 1.3e-30 105.3 1.4 9.2e-16 57.7 0.1 3.3 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFQ97051.1 - 1.6e-18 66.9 0.2 6.8e-14 52.1 0.1 2.6 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) TIR_2 PF13676.6 KFQ97051.1 - 2.3e-13 50.8 0.1 1.3e-12 48.3 0.0 2.2 2 0 0 2 2 2 1 TIR domain SAM_3 PF18016.1 KFQ97051.1 - 1.1e-05 25.2 0.1 4.8e-05 23.1 0.1 2.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Hemopexin PF00045.19 KFQ97052.1 - 7e-52 173.1 16.5 4e-17 61.9 0.1 5.4 5 0 0 5 5 5 5 Hemopexin Somatomedin_B PF01033.17 KFQ97052.1 - 4.9e-10 39.7 19.1 9e-10 38.8 19.1 1.5 1 0 0 1 1 1 1 Somatomedin B domain Kinesin PF00225.23 KFQ97053.1 - 1.2e-87 294.0 0.0 1.4e-87 293.7 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFQ97053.1 - 1.5e-20 73.6 0.0 2.5e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding DUF525 PF04379.14 KFQ97054.1 - 4.2e-27 94.2 0.1 7.2e-27 93.5 0.1 1.4 1 0 0 1 1 1 1 ApaG domain YccV-like PF08755.11 KFQ97054.1 - 4.7e-13 49.5 0.5 2.3e-12 47.3 0.1 2.1 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like zf-C2H2_4 PF13894.6 KFQ97056.1 - 1.9e-24 84.2 19.9 0.00013 22.5 0.6 5.8 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2 PF00096.26 KFQ97056.1 - 5.8e-24 83.2 30.8 6e-06 26.4 1.7 5.9 6 0 0 6 6 5 5 Zinc finger, C2H2 type BTB PF00651.31 KFQ97056.1 - 3.2e-23 82.1 0.0 4.6e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFQ97056.1 - 5.1e-21 74.1 24.0 1.5e-07 31.6 0.1 6.5 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFQ97056.1 - 4.4e-16 58.7 2.2 0.00037 20.7 0.2 5.7 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFQ97056.1 - 4.1e-12 45.8 21.5 0.0066 16.4 0.3 6.1 5 1 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 KFQ97056.1 - 3.1e-11 43.3 15.0 0.01 16.2 0.4 6.1 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 KFQ97056.1 - 8.1e-07 29.8 6.3 0.00017 22.3 0.4 4.0 1 1 2 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 KFQ97056.1 - 2.4e-06 27.2 14.8 0.11 12.3 0.3 5.0 5 0 0 5 5 5 3 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KFQ97056.1 - 9.8e-06 25.8 15.6 0.84 10.0 8.1 5.4 2 1 2 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_8 PF15909.5 KFQ97056.1 - 0.00033 20.9 8.9 0.13 12.6 0.0 3.6 2 1 2 4 4 4 1 C2H2-type zinc ribbon zf-Di19 PF05605.12 KFQ97056.1 - 0.0005 20.3 12.4 0.029 14.7 0.8 3.4 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 KFQ97056.1 - 0.00052 19.6 8.7 13 5.5 0.0 5.2 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf_C2H2_ZHX PF18387.1 KFQ97056.1 - 0.0076 15.9 6.4 1.5 8.5 0.2 3.7 4 0 0 4 4 4 1 Zinc-fingers and homeoboxes C2H2 finger domain Zn-ribbon_8 PF09723.10 KFQ97056.1 - 0.0083 16.2 13.2 0.1 12.8 1.1 4.1 2 1 2 4 4 4 2 Zinc ribbon domain zf-C2H2_9 PF16293.5 KFQ97056.1 - 0.011 15.5 2.2 8.5 6.3 0.0 4.0 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-UBP PF02148.19 KFQ97056.1 - 0.051 13.9 11.2 0.95 9.8 0.2 3.5 2 1 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein GAGA PF09237.11 KFQ97056.1 - 0.08 12.8 1.2 2 8.3 0.1 2.6 2 0 0 2 2 2 0 GAGA factor zf-H2C2_5 PF13909.6 KFQ97056.1 - 0.16 11.7 24.3 4.1 7.2 0.5 5.0 5 0 0 5 5 5 0 C2H2-type zinc-finger domain LIM PF00412.22 KFQ97056.1 - 0.19 12.0 0.3 0.19 12.0 0.3 3.9 3 1 2 5 5 4 0 LIM domain zinc_ribbon_15 PF17032.5 KFQ97056.1 - 0.23 12.3 8.4 15 6.4 0.1 3.6 2 1 2 4 4 4 0 zinc-ribbon family zf-C2HE PF16278.5 KFQ97056.1 - 0.39 11.2 12.9 19 5.8 0.5 5.0 2 1 3 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger zf-AN1 PF01428.16 KFQ97056.1 - 0.61 10.3 14.2 19 5.6 0.2 4.9 5 0 0 5 5 4 0 AN1-like Zinc finger HNH_5 PF14279.6 KFQ97056.1 - 1.2 9.0 8.9 25 4.8 0.0 4.7 4 1 0 4 4 4 0 HNH endonuclease DZR PF12773.7 KFQ97056.1 - 2.2 8.4 14.4 1.4e+03 -0.6 10.8 4.2 2 1 0 2 2 2 0 Double zinc ribbon zf-HYPF PF07503.12 KFQ97056.1 - 2.9 7.7 9.1 9.5 6.1 1.4 3.7 3 1 0 3 3 3 0 HypF finger C1_1 PF00130.22 KFQ97056.1 - 3.7 7.5 9.4 0.68 9.9 0.2 3.6 2 1 3 5 5 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-LYAR PF08790.11 KFQ97056.1 - 7.7 6.5 10.8 3.9 7.5 0.0 4.2 5 0 0 5 5 4 0 LYAR-type C2HC zinc finger C1_4 PF07975.12 KFQ97056.1 - 8.2 6.7 9.7 14 6.0 0.6 3.4 2 1 0 3 3 3 0 TFIIH C1-like domain Rep_fac-A_C PF08646.10 KFQ97057.1 - 3e-55 186.0 13.5 4.5e-52 175.7 8.6 2.7 3 0 0 3 3 3 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KFQ97057.1 - 3e-39 132.9 1.0 4.1e-37 126.0 0.4 2.4 2 0 0 2 2 2 2 Replication protein A OB domain Rep-A_N PF04057.12 KFQ97057.1 - 2.1e-27 95.1 0.2 4.1e-27 94.2 0.2 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KFQ97057.1 - 9.8e-13 47.9 0.5 6.2e-11 42.1 0.0 3.2 2 1 1 3 3 3 1 OB-fold nucleic acid binding domain DUF5521 PF17659.1 KFQ97057.1 - 0.001 17.0 0.1 0.0031 15.5 0.0 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5521) DUF4939 PF16297.5 KFQ97057.1 - 0.029 14.3 0.1 0.13 12.1 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4939) IBR PF01485.21 KFQ97057.1 - 0.098 12.9 3.7 0.27 11.5 3.7 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain SET PF00856.28 KFQ97058.1 - 9.6e-14 52.1 0.0 9.8e-13 48.8 0.0 2.6 2 1 0 2 2 2 1 SET domain TPR_12 PF13424.6 KFQ97058.1 - 5.6e-07 29.8 2.6 2.3e-05 24.6 0.5 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-MYND PF01753.18 KFQ97058.1 - 7.7e-07 29.1 13.9 7.7e-07 29.1 13.9 3.4 3 1 0 3 3 2 1 MYND finger TPR_2 PF07719.17 KFQ97058.1 - 2.5e-06 27.2 3.6 0.0069 16.4 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ97058.1 - 9.7e-05 22.1 0.4 0.00073 19.3 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ97058.1 - 0.00015 21.4 0.5 0.089 12.7 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ97058.1 - 0.00051 20.6 4.8 0.088 13.7 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ97058.1 - 0.0025 18.0 5.2 1 9.7 1.0 3.8 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KFQ97058.1 - 0.004 17.1 2.0 0.014 15.4 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFQ97058.1 - 0.0068 15.8 5.4 0.075 12.4 3.0 2.4 2 0 0 2 2 2 1 MalT-like TPR region TPR_16 PF13432.6 KFQ97058.1 - 0.012 16.3 4.0 4.8 7.9 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFQ97058.1 - 0.027 15.1 8.6 0.18 12.6 0.8 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ97058.1 - 0.12 12.9 6.9 3.5 8.2 0.2 3.7 2 1 0 2 2 2 0 Tetratricopeptide repeat YfdX PF10938.8 KFQ97058.1 - 0.15 12.0 0.5 3.6 7.5 0.1 2.4 2 0 0 2 2 2 0 YfdX protein Serpin PF00079.20 KFQ97059.1 - 8.5e-88 295.2 0.4 9.7e-88 295.0 0.4 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFQ97060.1 - 3.4e-87 293.2 1.7 3.9e-87 293.0 1.7 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) WD40 PF00400.32 KFQ97061.1 - 5.1e-16 58.8 5.9 1.6e-06 28.7 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ97061.1 - 0.0019 18.5 0.0 0.22 11.8 0.0 3.5 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KFQ97061.1 - 0.011 15.3 0.0 0.13 11.8 0.0 2.4 3 0 0 3 3 3 0 PQQ-like domain Calponin PF00402.18 KFQ97064.1 - 2e-43 145.6 23.6 4.5e-15 55.0 2.6 3.6 3 0 0 3 3 3 3 Calponin family repeat CH PF00307.31 KFQ97064.1 - 6.4e-23 81.0 0.0 9.6e-23 80.4 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFQ97064.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 CAMSAP CH domain DUF1989 PF09347.10 KFQ97064.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1989) Beta-APP PF03494.13 KFQ97064.1 - 0.13 12.1 1.1 7.7 6.5 0.0 3.0 3 0 0 3 3 3 0 Beta-amyloid peptide (beta-APP) CDC24 PF06395.11 KFQ97064.1 - 0.16 12.2 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 CDC24 Calponin GH43_C2 PF17851.1 KFQ97064.1 - 0.16 11.6 0.5 0.75 9.5 0.1 1.9 1 1 0 2 2 2 0 Beta xylosidase C-terminal Concanavalin A-like domain RRM_1 PF00076.22 KFQ97065.1 - 3.8e-41 138.8 0.0 1.2e-21 76.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFQ97065.1 - 3.2e-07 30.0 0.0 1.5e-05 24.6 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CysA_C_terminal PF17850.1 KFQ97067.1 - 0.22 12.1 3.1 34 5.1 3.1 3.0 1 1 0 1 1 1 0 CysA C-terminal regulatory domain Neurexophilin PF06312.12 KFQ97068.1 - 7.8e-112 371.8 2.7 1e-111 371.5 2.7 1.1 1 0 0 1 1 1 1 Neurexophilin NigD_C PF17415.2 KFQ97068.1 - 0.071 13.2 0.1 0.79 9.8 0.0 2.2 2 0 0 2 2 2 0 NigD-like C-terminal beta sandwich domain Filamin PF00630.19 KFQ97068.1 - 0.078 13.8 0.0 0.27 12.1 0.0 1.9 2 0 0 2 2 2 0 Filamin/ABP280 repeat Arfaptin PF06456.13 KFQ97069.1 - 6.6e-89 297.4 11.9 9.4e-89 296.9 11.9 1.2 1 0 0 1 1 1 1 Arfaptin-like domain ICA69 PF04629.14 KFQ97069.1 - 3.4e-60 204.5 17.8 6.5e-41 141.3 8.6 2.9 1 1 1 2 2 2 2 Islet cell autoantigen ICA69, C-terminal domain BAR_2 PF10455.9 KFQ97069.1 - 0.0012 18.1 2.8 0.0012 18.1 1.7 1.7 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Ead_Ea22 PF13935.6 KFQ97069.1 - 0.33 11.6 2.4 0.87 10.2 2.4 2.0 1 1 0 1 1 1 0 Ead/Ea22-like protein FAM117 PF15388.6 KFQ97070.1 - 1.7e-123 412.1 19.5 1.7e-123 412.1 19.5 1.9 2 0 0 2 2 2 1 Protein Family FAM117 DUF2464 PF10240.9 KFQ97071.1 - 0.016 14.8 0.0 0.017 14.7 0.0 1.0 1 0 0 1 1 1 0 Multivesicular body subunit 12 Rep_fac-A_3 PF08661.11 KFQ97073.1 - 5e-29 100.7 0.0 6.1e-29 100.5 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 SUKH-3 PF14433.6 KFQ97073.1 - 0.12 12.8 0.1 17 5.8 0.0 2.6 1 1 2 3 3 3 0 SUKH-3 immunity protein zinc_ribbon_16 PF17034.5 KFQ97074.1 - 6.9e-24 84.4 14.3 1.5e-23 83.3 14.3 1.6 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 KFQ97074.1 - 0.011 15.4 10.8 0.011 15.4 10.8 2.7 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type CheB_methylest PF01339.17 KFQ97074.1 - 0.092 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 CheB methylesterase Fringe PF02434.16 KFQ97075.1 - 6.5e-15 55.3 0.7 3e-14 53.1 0.7 1.9 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 KFQ97075.1 - 2.7e-09 37.1 0.3 4.1e-05 23.5 0.2 2.2 1 1 1 2 2 2 2 Galactosyltransferase Asn_synthase PF00733.21 KFQ97076.1 - 1.4e-84 284.8 0.5 1.1e-47 163.5 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KFQ97076.1 - 7.8e-26 90.4 0.0 1.4e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KFQ97076.1 - 4.8e-19 68.9 0.0 1e-18 67.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KFQ97076.1 - 6.8e-08 32.2 0.0 1.5e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KFQ97076.1 - 0.014 14.5 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 NAD synthase QueC PF06508.13 KFQ97076.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KFQ97076.1 - 0.05 12.4 0.0 0.073 11.8 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Homeodomain PF00046.29 KFQ97079.1 - 7.2e-21 73.8 2.4 9.8e-21 73.4 2.4 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ97079.1 - 0.0028 17.5 0.1 0.0054 16.6 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain DUF5524 PF17662.1 KFQ97079.1 - 0.01 15.2 0.1 0.4 10.0 0.0 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5524) Homez PF11569.8 KFQ97079.1 - 0.029 13.8 0.1 0.052 13.0 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez YdaS_antitoxin PF15943.5 KFQ97079.1 - 0.049 13.5 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF3199 PF11436.8 KFQ97079.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3199) DSS1_SEM1 PF05160.13 KFQ97080.1 - 1.6e-13 50.5 11.2 1.7e-13 50.4 11.2 1.0 1 0 0 1 1 1 1 DSS1/SEM1 family Mito_carr PF00153.27 KFQ97081.1 - 2.6e-73 242.0 0.6 1.5e-26 92.2 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KFQ97081.1 - 4.7e-09 36.6 0.6 0.00083 19.8 0.0 4.8 3 2 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KFQ97081.1 - 2.2e-08 33.1 3.8 0.031 13.8 0.1 4.9 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 KFQ97081.1 - 1.1e-07 31.2 1.5 0.0083 16.0 0.1 5.1 5 0 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 KFQ97081.1 - 1.7e-07 31.0 0.5 0.026 14.3 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 KFQ97081.1 - 4.3e-05 22.8 0.1 0.94 9.1 0.0 3.9 3 0 0 3 3 3 2 EF hand WD40 PF00400.32 KFQ97082.1 - 1.1e-08 35.5 9.7 0.059 14.3 0.3 6.8 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ97082.1 - 0.03 14.6 0.2 0.57 10.5 0.1 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain BCDHK_Adom3 PF10436.9 KFQ97083.1 - 1.5e-47 161.4 0.0 2.1e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KFQ97083.1 - 1.1e-13 51.6 0.0 1.9e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFQ97083.1 - 0.00021 21.1 0.0 0.00039 20.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ank_4 PF13637.6 KFQ97084.1 - 2.7e-25 88.4 7.6 3.9e-07 30.5 0.3 7.1 2 1 5 7 7 7 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFQ97084.1 - 5.6e-25 87.7 8.8 2.1e-12 47.5 1.3 4.6 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFQ97084.1 - 2.1e-20 70.6 13.8 0.0013 19.1 0.0 9.2 9 1 0 9 9 9 6 Ankyrin repeat Ank PF00023.30 KFQ97084.1 - 3e-19 68.5 12.3 0.056 13.9 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KFQ97084.1 - 1.6e-15 56.9 10.3 0.00041 20.6 0.1 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFQ97084.1 - 3.6e-11 43.2 5.0 7.6e-11 42.2 5.0 1.6 1 0 0 1 1 1 1 SOCS box Arylesterase PF01731.20 KFQ97085.1 - 2.8e-40 136.4 1.4 4.9e-40 135.6 1.4 1.4 1 0 0 1 1 1 1 Arylesterase SGL PF08450.12 KFQ97085.1 - 7.5e-08 32.3 0.0 1.1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KFQ97085.1 - 0.0038 17.3 0.0 0.01 15.9 0.0 1.7 1 0 0 1 1 1 1 Strictosidine synthase Glyco_hydro_42C PF08533.10 KFQ97085.1 - 0.061 13.0 0.2 0.58 9.9 0.2 2.4 1 1 0 1 1 1 0 Beta-galactosidase C-terminal domain SAM_2 PF07647.17 KFQ97086.1 - 5.5e-17 61.6 0.8 9.3e-17 60.9 0.8 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFQ97086.1 - 2.9e-14 53.2 1.0 5.6e-14 52.3 1.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFQ97086.1 - 0.0059 16.5 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain 7tm_4 PF13853.6 KFQ97088.1 - 1.9e-41 142.6 11.8 2.1e-41 142.5 11.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ97088.1 - 9.1e-24 84.2 16.7 1.1e-23 83.9 16.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFQ97088.1 - 0.0034 17.0 12.2 0.0069 16.0 12.2 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2417 PF10329.9 KFQ97088.1 - 0.2 11.0 3.3 0.38 10.1 3.3 1.4 1 0 0 1 1 1 0 Region of unknown function (DUF2417) zf-C4H2 PF10146.9 KFQ97092.1 - 1.3e-76 257.6 20.7 1.5e-76 257.4 20.7 1.0 1 0 0 1 1 1 1 Zinc finger-containing protein Sec20 PF03908.13 KFQ97092.1 - 0.0058 16.5 0.6 0.014 15.3 0.2 1.8 1 1 0 1 1 1 1 Sec20 DZR PF12773.7 KFQ97092.1 - 0.007 16.4 1.0 0.013 15.6 1.0 1.4 1 0 0 1 1 1 1 Double zinc ribbon CENP-O PF09496.10 KFQ97092.1 - 0.028 14.4 3.2 0.044 13.8 3.2 1.5 1 1 0 1 1 1 0 Cenp-O kinetochore centromere component DUF16 PF01519.16 KFQ97092.1 - 0.04 14.4 1.1 0.04 14.4 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 zf-C3HC4_3 PF13920.6 KFQ97092.1 - 0.062 13.2 4.2 0.1 12.4 4.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Tup_N PF08581.10 KFQ97092.1 - 0.079 13.3 9.1 0.45 10.9 9.1 2.2 1 1 0 1 1 1 0 Tup N-terminal zf-P11 PF03854.14 KFQ97092.1 - 0.081 12.6 2.2 0.16 11.7 2.2 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.6 KFQ97092.1 - 0.11 12.3 2.7 0.21 11.4 2.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain BLOC1_2 PF10046.9 KFQ97092.1 - 0.12 12.7 8.1 4.3 7.7 0.9 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3365 PF11845.8 KFQ97092.1 - 0.17 12.2 3.4 0.22 11.8 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) Cytochrom_C_2 PF01322.20 KFQ97092.1 - 0.17 12.7 0.5 0.17 12.7 0.5 2.2 2 1 0 2 2 2 0 Cytochrome C' Fez1 PF06818.15 KFQ97092.1 - 0.2 12.1 12.6 0.37 11.2 12.6 1.4 1 0 0 1 1 1 0 Fez1 Spc7 PF08317.11 KFQ97092.1 - 0.22 10.3 15.0 0.055 12.3 12.1 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 KFQ97092.1 - 0.42 10.7 4.3 1.1 9.3 4.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) HeLo PF14479.6 KFQ97092.1 - 1.8 8.4 6.8 13 5.5 6.8 2.1 1 1 0 1 1 1 0 Prion-inhibition and propagation TMF_TATA_bd PF12325.8 KFQ97092.1 - 3.3 7.9 16.0 7.9 6.7 7.9 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.19 KFQ97092.1 - 3.5 5.4 7.0 3.9 5.3 7.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WAC_Acf1_DNA_bd PF10537.9 KFQ97092.1 - 3.9 8.1 7.4 2.8 8.5 1.3 2.3 1 1 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal YabA PF06156.13 KFQ97092.1 - 5.3 7.7 12.7 0.86 10.3 3.7 2.5 1 1 1 2 2 2 0 Initiation control protein YabA DASH_Dad1 PF08649.10 KFQ97092.1 - 5.7 7.2 6.6 1.2 9.4 0.5 2.6 3 0 0 3 3 3 0 DASH complex subunit Dad1 LMBR1 PF04791.16 KFQ97092.1 - 6.4 5.6 4.9 7.4 5.4 4.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TSNAXIP1_N PF15739.5 KFQ97092.1 - 6.5 7.2 13.8 0.68 10.3 6.8 2.5 2 1 1 3 3 3 0 Translin-associated factor X-interacting N-terminus FUSC PF04632.12 KFQ97092.1 - 7.5 5.0 10.0 15 4.0 9.9 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family FapA PF03961.13 KFQ97092.1 - 7.6 5.0 8.1 9.5 4.7 8.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3450 PF11932.8 KFQ97092.1 - 9.5 5.4 17.9 0.54 9.5 4.6 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) RNase_Zc3h12a PF11977.8 KFQ97093.1 - 4.7e-66 221.4 0.0 6.2e-66 221.0 0.0 1.2 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain UBA_6 PF18039.1 KFQ97093.1 - 3.6e-19 68.4 0.2 9e-19 67.1 0.2 1.7 1 0 0 1 1 1 1 UBA-like domain zf-CCCH_4 PF18044.1 KFQ97093.1 - 7.5e-05 22.4 7.0 0.00018 21.3 7.0 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger PRORP PF16953.5 KFQ97093.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein-only RNase P Omega-toxin PF06357.11 KFQ97093.1 - 0.89 9.4 7.8 0.083 12.7 3.0 1.7 2 0 0 2 2 2 0 Omega-atracotoxin zf-CCCH_2 PF14608.6 KFQ97093.1 - 1.1 9.9 9.6 2.6 8.6 9.6 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 KFQ97093.1 - 1.1 9.3 8.3 9.3 6.3 8.3 2.2 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Las1 PF04031.13 KFQ97095.1 - 7.5e-32 110.6 0.0 1e-31 110.2 0.0 1.2 1 0 0 1 1 1 1 Las1-like ERM PF00769.19 KFQ97096.1 - 4.3e-72 242.9 74.3 4.3e-72 242.9 74.3 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_C PF09380.10 KFQ97096.1 - 9.3e-28 96.5 0.0 3.6e-27 94.6 0.0 2.1 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 KFQ97096.1 - 2e-27 95.9 0.4 2e-27 95.9 0.4 3.8 2 1 1 3 3 3 1 FERM central domain FERM_N PF09379.10 KFQ97096.1 - 5.1e-15 55.2 0.5 6.3e-14 51.7 0.1 2.6 2 0 0 2 2 2 1 FERM N-terminal domain Fer2 PF00111.27 KFQ97097.1 - 2.8e-07 30.4 0.5 3.9e-07 29.9 0.5 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain RhoGAP PF00620.27 KFQ97098.1 - 6.4e-36 123.5 0.1 8.9e-35 119.8 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 KFQ97098.1 - 1.4e-05 25.5 0.1 4.4e-05 23.9 0.1 1.9 1 0 0 1 1 1 1 PH domain RA PF00788.23 KFQ97098.1 - 5.1e-05 23.8 0.0 0.00011 22.7 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ras_bdg_2 PF14847.6 KFQ97098.1 - 0.0019 18.5 0.0 0.012 15.9 0.0 2.3 2 0 0 2 2 2 1 Ras-binding domain of Byr2 YhfZ_C PF14503.6 KFQ97098.1 - 0.1 12.1 0.1 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 YhfZ C-terminal domain V-set PF07686.17 KFQ97099.1 - 1.4e-17 63.8 1.3 6.8e-12 45.5 0.3 3.1 2 1 1 3 3 3 3 Immunoglobulin V-set domain Ig_3 PF13927.6 KFQ97099.1 - 1.3e-16 61.0 0.2 9.1e-10 39.0 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFQ97099.1 - 2.4e-14 53.3 0.2 4.2e-06 26.8 0.2 2.5 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFQ97099.1 - 2.7e-12 46.8 1.0 3.8e-06 27.1 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFQ97099.1 - 6.7e-11 42.1 0.0 0.00029 20.8 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_6 PF18452.1 KFQ97099.1 - 0.0019 17.7 0.0 0.15 11.6 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFQ97099.1 - 0.0019 18.2 0.0 0.76 9.9 0.0 2.4 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 KFQ97099.1 - 0.0058 16.6 0.3 6.9 6.8 0.2 2.9 2 1 0 2 2 2 2 C17orf99 Ig domain V-set_CD47 PF08204.11 KFQ97099.1 - 0.018 15.0 0.0 0.075 13.0 0.0 1.9 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain TIG_2 PF18020.1 KFQ97099.1 - 0.16 12.6 0.0 0.28 11.8 0.0 1.4 1 0 0 1 1 1 0 TIG domain found in plexin V-set PF07686.17 KFQ97100.1 - 2.4e-14 53.4 0.2 2.8e-11 43.5 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.6 KFQ97100.1 - 8.3e-10 39.1 0.1 0.0016 19.0 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFQ97100.1 - 1.2e-08 34.9 0.0 5.3e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFQ97100.1 - 3e-07 30.5 0.1 0.0058 16.8 0.1 2.5 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFQ97100.1 - 1.9e-06 28.1 0.3 0.0016 18.7 0.1 2.8 2 2 1 3 3 3 2 Immunoglobulin domain Ig_6 PF18452.1 KFQ97100.1 - 0.00013 21.5 0.0 0.024 14.2 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFQ97100.1 - 0.029 14.4 0.0 4.3 7.5 0.0 2.5 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Cu-oxidase_2 PF07731.14 KFQ97101.1 - 1.8e-29 102.2 14.2 4.9e-13 49.0 1.8 6.5 6 1 0 6 6 6 5 Multicopper oxidase Cu-oxidase_3 PF07732.15 KFQ97101.1 - 4.8e-27 94.3 4.0 4.8e-08 33.0 0.0 5.6 6 0 0 6 6 6 3 Multicopper oxidase 7tm_1 PF00001.21 KFQ97102.1 - 1.7e-52 178.3 30.0 1.8e-52 178.3 29.2 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ97102.1 - 3e-14 53.0 28.4 3.8e-14 52.7 28.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFQ97102.1 - 0.0085 15.9 17.2 0.012 15.3 16.7 1.6 1 1 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ97103.1 - 7.7e-53 179.5 22.4 1e-52 179.1 22.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ97103.1 - 7.7e-16 58.2 21.9 9.7e-16 57.9 21.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFQ97103.1 - 6.2e-05 22.9 19.6 9.2e-05 22.3 19.6 1.3 1 1 0 1 1 1 1 Olfactory receptor Hormone_recep PF00104.30 KFQ97104.1 - 1.7e-31 109.5 2.7 3e-31 108.6 2.7 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFQ97104.1 - 1.5e-27 95.8 14.4 2.7e-27 95.0 14.4 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) E2F_TDP PF02319.20 KFQ97104.1 - 0.071 13.2 0.1 0.28 11.3 0.0 2.0 2 0 0 2 2 2 0 E2F/DP family winged-helix DNA-binding domain Yip1 PF04893.17 KFQ97105.1 - 4.1e-18 65.7 15.3 7.2e-18 64.9 14.4 1.7 1 1 0 1 1 1 1 Yip1 domain LRR_8 PF13855.6 KFQ97106.1 - 7.6e-46 153.7 30.3 1.5e-14 53.5 3.7 5.2 2 2 3 5 5 5 4 Leucine rich repeat 7tm_1 PF00001.21 KFQ97106.1 - 1.7e-24 86.6 7.6 2.9e-24 85.8 7.6 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_5 PF13306.6 KFQ97106.1 - 6.1e-17 61.8 0.0 8.7e-08 32.2 0.0 2.4 1 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFQ97106.1 - 3e-14 52.9 29.4 4.6e-05 23.7 0.4 6.5 3 2 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFQ97106.1 - 7.8e-11 41.8 13.2 3.4e-06 26.7 0.1 4.0 1 1 2 3 3 3 3 Leucine-rich repeat Ldl_recept_a PF00057.18 KFQ97106.1 - 2e-08 34.3 5.8 4.4e-08 33.2 5.8 1.6 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A LRRNT PF01462.18 KFQ97106.1 - 0.00034 20.2 0.2 0.00098 18.7 0.2 1.8 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KFQ97106.1 - 0.00065 19.9 29.1 4.3 8.3 0.1 9.6 10 1 1 11 11 11 2 Leucine Rich Repeat Ephrin PF00812.17 KFQ97108.1 - 2e-42 144.5 1.8 4.2e-42 143.4 0.2 2.0 2 0 0 2 2 2 1 Ephrin DUF4381 PF14316.6 KFQ97108.1 - 0.0064 16.7 0.0 0.0096 16.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) Baculo_11_kDa PF06143.11 KFQ97108.1 - 0.01 15.4 0.7 0.019 14.5 0.7 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family Shisa PF13908.6 KFQ97108.1 - 0.023 14.9 0.1 0.056 13.7 0.1 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 KFQ97108.1 - 0.04 14.8 0.0 0.076 13.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Glucos_trans_II PF14264.6 KFQ97108.1 - 0.052 12.9 0.0 0.065 12.6 0.0 1.1 1 0 0 1 1 1 0 Glucosyl transferase GtrII WBP-1 PF11669.8 KFQ97108.1 - 0.06 14.0 0.0 0.17 12.5 0.0 1.7 1 0 0 1 1 1 0 WW domain-binding protein 1 Cytomega_TRL10 PF06084.11 KFQ97108.1 - 0.062 13.3 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein TMEM132D_C PF15706.5 KFQ97108.1 - 0.068 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Orthoreo_P10 PF07204.11 KFQ97108.1 - 0.079 12.9 0.2 0.15 12.1 0.2 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 PalH PF08733.10 KFQ97108.1 - 0.088 11.8 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 PalH/RIM21 ECSCR PF15820.5 KFQ97108.1 - 0.093 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Syndecan PF01034.20 KFQ97108.1 - 0.14 12.1 4.7 0.26 11.2 4.7 1.4 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 KFQ97108.1 - 0.18 11.2 2.5 0.37 10.2 2.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Stevor PF17410.2 KFQ97108.1 - 0.26 10.8 1.2 0.29 10.7 0.3 1.4 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Fz PF01392.22 KFQ97109.1 - 0.38 11.4 9.8 0.96 10.1 9.8 1.8 1 1 0 1 1 1 0 Fz domain SelP_N PF04592.14 KFQ97109.1 - 1.4 8.3 16.0 2.3 7.6 16.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TNF PF00229.18 KFQ97110.1 - 3.7e-09 36.6 0.4 1.7e-08 34.4 0.4 1.9 1 1 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Collagen PF01391.18 KFQ97110.1 - 1.4e-07 31.1 45.9 0.00012 21.8 45.9 2.6 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) LRR_8 PF13855.6 KFQ97111.1 - 1.5e-58 194.4 58.9 8e-12 44.7 1.1 10.0 5 2 5 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 KFQ97111.1 - 1.1e-41 140.1 62.2 2.5e-07 30.9 0.0 11.1 8 2 4 12 12 12 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFQ97111.1 - 1.6e-17 61.3 54.6 2.4 9.0 0.4 17.9 19 1 0 19 19 19 9 Leucine Rich Repeat LRR_6 PF13516.6 KFQ97111.1 - 2.7e-11 42.6 63.6 2.6 8.3 0.6 17.5 18 0 0 18 18 18 7 Leucine Rich repeat LRR_9 PF14580.6 KFQ97111.1 - 2.6e-07 30.3 10.4 0.007 15.9 0.3 6.5 3 2 4 7 7 7 2 Leucine-rich repeat LRR_5 PF13306.6 KFQ97111.1 - 1.7e-06 28.1 0.0 0.063 13.2 0.0 3.6 4 0 0 4 4 4 2 BspA type Leucine rich repeat region (6 copies) LRRNT PF01462.18 KFQ97111.1 - 0.012 15.3 0.1 0.044 13.5 0.1 2.1 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain wnt PF00110.19 KFQ97112.1 - 1.3e-111 373.1 9.7 1.5e-111 372.9 9.7 1.0 1 0 0 1 1 1 1 wnt family TAP42 PF04177.12 KFQ97113.1 - 3.9e-74 249.7 0.1 4.5e-74 249.4 0.1 1.0 1 0 0 1 1 1 1 TAP42-like family Phage_prot_Gp6 PF05133.14 KFQ97113.1 - 0.11 11.6 2.0 0.17 11.0 2.0 1.3 1 0 0 1 1 1 0 Phage portal protein, SPP1 Gp6-like Ribosomal_60s PF00428.19 KFQ97113.1 - 0.27 11.8 5.8 0.32 11.6 0.8 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein DAGAT PF03982.13 KFQ97114.1 - 1e-118 395.6 0.0 1.2e-118 395.4 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF2852 PF11014.8 KFQ97114.1 - 0.27 11.4 1.4 0.55 10.4 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) Arrestin_N PF00339.29 KFQ97116.1 - 1.7e-40 138.5 0.1 6.9e-37 126.7 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KFQ97116.1 - 3.2e-25 89.1 0.8 5.3e-25 88.4 0.8 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain BatD PF13584.6 KFQ97116.1 - 0.046 12.5 0.0 0.061 12.1 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance CBM49 PF09478.10 KFQ97116.1 - 0.17 12.3 0.6 0.3 11.4 0.6 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain CBM49 Ras PF00071.22 KFQ97117.1 - 2e-55 186.8 0.4 2.5e-55 186.5 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ97117.1 - 8e-32 110.0 0.2 1.5e-31 109.1 0.2 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ97117.1 - 1.5e-12 47.3 0.5 1.7e-12 47.1 0.5 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFQ97117.1 - 4.3e-06 26.4 0.1 9.2e-06 25.3 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFQ97117.1 - 0.001 18.5 0.1 0.0015 18.0 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFQ97117.1 - 0.0087 16.1 0.1 0.014 15.4 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFQ97117.1 - 0.014 14.9 0.0 0.032 13.8 0.0 1.7 1 0 0 1 1 1 0 Ferrous iron transport protein B PDZ PF00595.24 KFQ97118.1 - 2.3e-17 63.1 0.2 2.7e-17 62.9 0.2 1.0 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFQ97118.1 - 2.7e-10 39.9 0.1 4.5e-10 39.2 0.0 1.4 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KFQ97118.1 - 3.2e-08 33.8 0.0 3.4e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 PDZ domain Kinesin PF00225.23 KFQ97119.1 - 9.3e-116 386.4 0.0 9.3e-116 386.4 0.0 3.0 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KFQ97119.1 - 1.2e-23 83.7 0.0 1.2e-23 83.7 0.0 3.6 4 1 0 4 4 4 1 Microtubule binding TCR PF03638.15 KFQ97119.1 - 2.2 8.6 19.6 5.2 7.5 19.6 1.6 1 0 0 1 1 1 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain TFIID-31kDa PF02291.15 KFQ97121.1 - 4.2e-32 110.8 0.0 6.7e-32 110.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 KFQ97121.1 - 0.018 15.4 0.1 0.04 14.3 0.1 1.6 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KFQ97121.1 - 0.02 15.2 0.1 0.042 14.2 0.1 1.5 1 0 0 1 1 1 0 CENP-S protein CENP-T_C PF15511.6 KFQ97121.1 - 0.12 12.5 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold 7tm_1 PF00001.21 KFQ97122.1 - 3.9e-06 26.4 16.3 4.7e-06 26.1 16.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFQ97122.1 - 0.061 13.0 16.5 0.1 12.2 16.5 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 KFQ97123.1 - 2.3e-52 177.9 24.5 2.3e-52 177.9 24.5 1.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ97123.1 - 4.3e-08 32.8 26.8 6e-08 32.4 26.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 KFQ97123.1 - 0.00095 18.5 30.0 0.0058 16.0 30.0 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Serpentine_r_xa PF03383.15 KFQ97123.1 - 0.18 11.8 17.7 0.048 13.6 2.9 2.7 1 1 1 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa 7TM_GPCR_Srx PF10328.9 KFQ97123.1 - 0.38 10.3 34.7 1.2 8.7 32.9 2.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 KFQ97124.1 - 3.5e-36 124.9 24.3 4.8e-36 124.4 24.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2975 PF11188.8 KFQ97124.1 - 1.2 9.0 11.1 0.97 9.3 5.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) 7tm_1 PF00001.21 KFQ97125.1 - 2.3e-41 141.8 20.5 3e-41 141.5 20.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3318 PF11780.8 KFQ97125.1 - 0.065 13.2 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) 7tm_1 PF00001.21 KFQ97126.1 - 7.4e-39 133.6 17.0 8.7e-39 133.4 17.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFQ97126.1 - 8.2e-05 22.0 1.2 8.2e-05 22.0 1.2 2.6 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw BRICHOS PF04089.14 KFQ97127.1 - 3.3e-18 65.7 0.0 7.4e-18 64.6 0.0 1.6 2 0 0 2 2 2 1 BRICHOS domain T-box PF00907.22 KFQ97128.1 - 8.4e-14 52.2 0.2 1.2e-13 51.7 0.2 1.2 1 0 0 1 1 1 1 T-box Snf7 PF03357.21 KFQ97129.1 - 3.7e-16 59.2 17.7 4.4e-16 59.0 17.7 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 KFQ97129.1 - 3.2e-05 23.9 7.6 4.4e-05 23.5 7.6 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway FlxA PF14282.6 KFQ97129.1 - 0.037 14.0 7.4 0.04 13.9 0.8 2.2 2 0 0 2 2 2 0 FlxA-like protein Mu-like_Pro PF10123.9 KFQ97129.1 - 0.047 13.2 9.1 0.059 12.9 9.1 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein DMSP_lyase PF16867.5 KFQ97129.1 - 0.11 12.1 0.2 0.18 11.4 0.2 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase DUF948 PF06103.11 KFQ97129.1 - 0.16 12.3 8.8 0.054 13.7 4.9 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Mt_ATP-synt_D PF05873.12 KFQ97129.1 - 0.23 11.3 10.1 0.4 10.5 0.6 2.6 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) GrpE PF01025.19 KFQ97129.1 - 0.64 9.7 10.6 1.1 8.9 10.5 1.4 1 1 0 1 1 1 0 GrpE NTP_transf_7 PF07984.12 KFQ97130.1 - 1.7e-158 526.9 3.2 2e-158 526.7 3.2 1.0 1 0 0 1 1 1 1 Nucleotidyltransferase Bromodomain PF00439.25 KFQ97131.1 - 1.3e-38 130.9 0.9 2.2e-18 66.1 0.0 2.6 2 0 0 2 2 2 2 Bromodomain WD40 PF00400.32 KFQ97131.1 - 3.1e-36 122.7 18.3 4.3e-06 27.3 0.2 8.6 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ97131.1 - 2.6e-06 27.6 0.2 0.19 12.1 0.2 5.0 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFQ97131.1 - 0.006 15.6 4.1 1.4 7.8 0.0 4.9 2 1 5 7 7 7 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Auxin_resp PF06507.13 KFQ97131.1 - 0.031 14.5 0.1 0.1 12.9 0.1 1.9 1 0 0 1 1 1 0 Auxin response factor Macoilin PF09726.9 KFQ97131.1 - 0.15 10.6 6.1 0.22 10.0 6.1 1.2 1 0 0 1 1 1 0 Macoilin family HMG14_17 PF01101.18 KFQ97132.1 - 6e-12 46.4 37.1 1.3e-11 45.3 37.1 1.5 1 1 0 1 1 1 1 HMG14 and HMG17 Pap_E4 PF02711.14 KFQ97132.1 - 5.7 8.0 11.3 16 6.5 11.3 1.7 1 1 0 1 1 1 0 E4 protein SH3BGR PF04908.15 KFQ97133.1 - 3.8e-36 123.2 0.1 4.5e-36 123.0 0.1 1.1 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 KFQ97133.1 - 0.00036 20.7 0.0 0.00056 20.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF4569 PF15133.6 KFQ97134.1 - 6.1e-107 357.8 1.8 6.8e-107 357.6 1.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4569) Na_H_Exchanger PF00999.21 KFQ97135.1 - 1.2e-78 264.6 33.4 1.4e-78 264.4 33.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NEXCaM_BD PF16644.5 KFQ97135.1 - 1.2e-11 44.9 0.1 1.7e-11 44.4 0.1 1.3 1 0 0 1 1 1 1 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin Claudin_2 PF13903.6 KFQ97136.1 - 8.1e-29 100.8 3.7 1.1e-28 100.3 3.7 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFQ97136.1 - 0.00039 20.4 8.3 0.014 15.3 5.2 2.7 2 1 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family Pkinase PF00069.25 KFQ97137.1 - 2.2e-145 482.9 0.0 1.3e-72 244.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ97137.1 - 5.4e-75 252.0 0.0 3.9e-40 137.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFQ97137.1 - 7.5e-13 48.4 0.0 3.5e-07 29.8 0.0 3.0 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 KFQ97137.1 - 2.6e-10 40.0 0.0 1.9e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFQ97137.1 - 2.7e-08 33.0 0.0 0.00097 18.0 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Haspin_kinase PF12330.8 KFQ97137.1 - 3.7e-07 29.4 0.3 0.0031 16.5 0.0 2.2 2 0 0 2 2 2 2 Haspin like kinase domain Pkinase_C PF00433.24 KFQ97137.1 - 3.4e-06 27.7 1.5 9.7e-06 26.2 1.5 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 KFQ97137.1 - 2.7e-05 24.2 0.1 0.24 11.3 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KFQ97137.1 - 0.0002 21.0 0.0 0.08 12.5 0.0 2.5 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL FTA2 PF13095.6 KFQ97137.1 - 0.00061 19.5 0.1 2.1 7.9 0.0 3.2 3 0 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KFQ97137.1 - 0.015 14.9 0.0 0.61 9.7 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.11 KFQ97137.1 - 0.13 11.2 0.1 1.8 7.4 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.20 KFQ97137.1 - 0.18 11.3 0.1 6.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase Homeodomain PF00046.29 KFQ97138.1 - 1.8e-11 43.7 2.2 5e-05 23.1 0.0 2.7 2 0 0 2 2 2 2 Homeodomain UDPG_MGDP_dh PF00984.19 KFQ97138.1 - 0.014 15.6 0.0 9.8 6.5 0.0 3.3 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain THEG4 PF15834.5 KFQ97138.1 - 3.3 7.7 7.6 2.9 7.8 0.2 2.6 3 0 0 3 3 3 0 Testis highly expressed protein 4 DUF1170 PF06663.13 KFQ97139.1 - 4.1e-56 190.1 3.6 5.7e-55 186.3 3.6 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1170) CRIC_ras_sig PF10534.9 KFQ97139.1 - 7.4e-38 128.6 1.1 1.9e-37 127.3 0.2 2.2 2 0 0 2 2 2 1 Connector enhancer of kinase suppressor of ras PH PF00169.29 KFQ97139.1 - 5.6e-15 55.7 2.9 1.4e-14 54.4 2.9 1.7 1 0 0 1 1 1 1 PH domain SAM_1 PF00536.30 KFQ97139.1 - 8.1e-15 55.0 0.3 2.6e-14 53.4 0.3 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ PF00595.24 KFQ97139.1 - 1e-09 38.6 0.0 1.3e-08 35.1 0.0 2.5 2 0 0 2 2 2 1 PDZ domain SAM_2 PF07647.17 KFQ97139.1 - 1.7e-09 37.7 0.6 5.6e-09 36.0 0.6 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ_6 PF17820.1 KFQ97139.1 - 2e-08 34.0 0.1 4.8e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFQ97139.1 - 0.0036 17.6 0.0 0.012 15.9 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PH_11 PF15413.6 KFQ97139.1 - 0.063 13.7 10.7 0.62 10.5 10.7 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.6 KFQ97139.1 - 0.084 13.2 2.1 2.9 8.3 1.1 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain Phage-MuB_C PF09077.11 KFQ97139.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 Mu B transposition protein, C terminal ApoO PF09769.9 KFQ97140.1 - 1.7e-38 131.5 0.0 2.9e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 Apolipoprotein O DUF2214 PF09980.9 KFQ97140.1 - 0.21 11.4 0.0 0.42 10.4 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2214) Zfx_Zfy_act PF04704.13 KFQ97141.1 - 1.4e-153 510.8 15.5 1.4e-153 510.8 15.5 1.8 2 0 0 2 2 2 1 Zfx / Zfy transcription activation region zf-C2H2 PF00096.26 KFQ97141.1 - 1.1e-40 135.8 116.6 2.6e-06 27.6 2.9 12.3 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ97141.1 - 5.2e-35 118.3 119.4 1.1e-05 25.6 2.6 13.1 13 0 0 13 13 13 11 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ97141.1 - 1.3e-31 106.5 110.8 0.0001 22.8 2.3 12.4 12 0 0 12 12 12 12 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFQ97141.1 - 1.2e-25 88.9 104.8 3.6e-07 29.8 0.9 12.4 12 0 0 12 12 12 8 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFQ97141.1 - 5.7e-10 39.2 82.1 0.016 15.5 0.1 11.9 12 0 0 12 12 12 6 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 KFQ97141.1 - 2.4e-07 31.4 48.1 0.012 16.3 2.7 7.1 4 2 3 7 7 7 4 zinc-ribbon family zf-C2H2_6 PF13912.6 KFQ97141.1 - 0.0081 16.1 11.4 0.012 15.7 3.9 8.4 8 0 0 8 8 7 3 C2H2-type zinc finger zf-met PF12874.7 KFQ97141.1 - 0.028 14.8 71.7 0.068 13.6 0.1 10.9 11 0 0 11 11 11 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFQ97141.1 - 0.044 13.6 0.5 0.044 13.6 0.5 10.3 11 0 0 11 11 11 0 zinc-finger C2H2-type Ribosomal_S17e PF00833.18 KFQ97141.1 - 0.086 12.8 0.6 0.22 11.5 0.6 1.6 1 0 0 1 1 1 0 Ribosomal S17 HypA PF01155.19 KFQ97141.1 - 9.3 6.3 38.6 1.1 9.3 2.9 6.3 1 1 4 5 5 5 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ATG16 PF08614.11 KFQ97142.1 - 0.0012 19.1 25.2 0.09 13.0 7.6 3.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) APG6_N PF17675.1 KFQ97142.1 - 0.028 15.0 11.5 0.028 15.0 11.5 3.2 1 1 1 3 3 3 0 Apg6 coiled-coil region Golgin_A5 PF09787.9 KFQ97142.1 - 0.037 13.5 21.9 0.22 11.0 11.9 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 PKcGMP_CC PF16808.5 KFQ97142.1 - 0.19 11.6 16.6 0.52 10.2 0.4 4.5 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HrcA PF01628.21 KFQ97142.1 - 0.49 10.3 5.3 0.44 10.4 3.5 1.8 1 1 0 1 1 1 0 HrcA protein C terminal domain Spc7 PF08317.11 KFQ97142.1 - 0.78 8.6 21.3 10 4.9 10.3 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein COQ7 PF03232.13 KFQ97142.1 - 1.5 8.6 6.2 4.1 7.1 0.0 3.2 2 1 0 3 3 3 0 Ubiquinone biosynthesis protein COQ7 DUF445 PF04286.12 KFQ97142.1 - 2.2 8.0 7.4 3.2 7.5 7.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) ERM PF00769.19 KFQ97142.1 - 5.5 6.7 22.0 0.091 12.6 14.1 2.0 2 1 0 2 2 2 0 Ezrin/radixin/moesin family DUF724 PF05266.14 KFQ97142.1 - 5.7 6.7 19.6 0.55 10.0 9.5 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF724) Latarcin PF10279.9 KFQ97142.1 - 7.5 7.0 7.4 38 4.8 7.4 2.3 1 1 0 1 1 1 0 Latarcin precursor GDI PF00996.18 KFQ97143.1 - 8.7e-55 186.0 0.1 6.3e-47 160.1 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KFQ97143.1 - 0.11 12.7 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain LMBR1 PF04791.16 KFQ97144.1 - 0.34 9.8 2.0 0.41 9.5 2.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DDE_Tnp_1_6 PF13751.6 KFQ97144.1 - 0.39 10.9 5.8 0.77 10.0 5.8 1.4 1 0 0 1 1 1 0 Transposase DDE domain DUF4778 PF16008.5 KFQ97144.1 - 1.4 8.9 9.7 3 7.8 9.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Kelch_1 PF01344.25 KFQ97145.1 - 1.1e-75 248.9 23.9 7.2e-15 54.3 0.1 6.7 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 KFQ97145.1 - 4.6e-47 156.9 7.3 1e-09 38.3 0.0 6.5 2 2 4 6 6 6 6 Kelch motif BACK PF07707.15 KFQ97145.1 - 4.4e-32 110.2 2.3 5.4e-32 110.0 0.0 2.3 3 0 0 3 3 3 1 BTB And C-terminal Kelch BTB PF00651.31 KFQ97145.1 - 4.2e-31 107.4 2.0 6.6e-31 106.8 0.9 1.9 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 KFQ97145.1 - 8.8e-25 85.7 8.2 4e-06 26.6 0.0 6.9 7 0 0 7 7 7 5 Kelch motif Kelch_4 PF13418.6 KFQ97145.1 - 1.7e-20 72.7 11.5 0.00029 20.8 0.1 6.3 3 1 3 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KFQ97145.1 - 4.5e-17 61.9 11.7 0.0093 16.2 0.2 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KFQ97145.1 - 4e-05 23.5 7.1 0.51 10.4 0.0 5.9 6 0 0 6 6 6 1 Kelch motif DUF3342 PF11822.8 KFQ97145.1 - 0.066 13.4 0.5 4.5 7.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3342) Hydrolase PF00702.26 KFQ97145.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1708 PF08101.11 KFQ97146.1 - 0.038 13.2 0.0 0.038 13.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) DUF4462 PF14692.6 KFQ97146.1 - 0.14 11.7 0.4 0.24 10.9 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) Cadherin PF00028.17 KFQ97148.1 - 6.2e-114 372.7 5.1 2.1e-22 79.4 0.1 7.5 7 0 0 7 7 7 7 Cadherin domain Protocadherin PF08374.11 KFQ97148.1 - 3.2e-85 285.5 3.5 5.1e-85 284.9 3.5 1.3 1 0 0 1 1 1 1 Protocadherin Cadherin_2 PF08266.12 KFQ97148.1 - 7.1e-20 70.6 0.1 1.2e-08 34.7 0.0 5.2 5 0 0 5 5 5 3 Cadherin-like Cadherin_3 PF16184.5 KFQ97148.1 - 1e-09 38.4 11.0 0.008 16.2 0.1 5.8 5 0 0 5 5 5 4 Cadherin-like Cadherin_4 PF17803.1 KFQ97148.1 - 0.0046 17.5 38.5 0.039 14.6 0.6 6.0 7 0 0 7 7 6 3 Bacterial cadherin-like domain Big_9 PF17963.1 KFQ97148.1 - 0.011 16.5 29.0 0.98 10.2 1.1 5.5 5 0 0 5 5 5 0 Bacterial Ig domain TMEM154 PF15102.6 KFQ97148.1 - 0.015 15.2 0.3 0.043 13.7 0.3 1.8 1 0 0 1 1 1 0 TMEM154 protein family RET_CLD1 PF17756.1 KFQ97148.1 - 0.017 15.4 0.0 2.4 8.5 0.0 2.9 2 0 0 2 2 2 0 RET Cadherin like domain 1 AP3D1 PF06375.11 KFQ97148.1 - 0.027 14.7 0.9 0.062 13.5 0.9 1.5 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Y_Y_Y PF07495.13 KFQ97148.1 - 0.052 13.5 0.0 1.4 8.9 0.0 3.4 3 0 0 3 3 3 0 Y_Y_Y domain Cadherin_C_2 PF16492.5 KFQ97148.1 - 0.11 13.2 0.1 1.2 9.9 0.0 2.6 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal EphA2_TM PF14575.6 KFQ97148.1 - 0.12 13.2 0.2 0.52 11.2 0.2 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain He_PIG PF05345.12 KFQ97148.1 - 1.1 9.4 9.2 3.7 7.8 0.1 4.9 5 1 0 5 5 4 0 Putative Ig domain BRICHOS PF04089.14 KFQ97151.1 - 2.2e-16 59.9 0.0 4e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 BRICHOS domain Tetraspanin PF00335.20 KFQ97152.1 - 5.8e-30 104.7 5.4 6.5e-30 104.5 5.4 1.0 1 0 0 1 1 1 1 Tetraspanin family FixQ PF05545.11 KFQ97152.1 - 0.0025 17.7 0.3 0.0046 16.9 0.3 1.4 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ DUF4190 PF13828.6 KFQ97152.1 - 0.057 13.2 4.0 0.56 10.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) FeoB_C PF07664.12 KFQ97152.1 - 0.74 9.5 4.3 0.41 10.4 0.3 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus DUF4174 PF13778.6 KFQ97153.1 - 2.2e-32 112.0 0.0 3.5e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) HYR PF02494.16 KFQ97153.1 - 1.8e-27 95.5 0.0 2.8e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 HYR domain Sushi PF00084.20 KFQ97153.1 - 2.7e-23 82.3 21.6 8.2e-11 42.3 6.5 3.6 3 0 0 3 3 3 3 Sushi repeat (SCR repeat) cEGF PF12662.7 KFQ97153.1 - 3.1 7.8 16.5 0.38 10.7 1.7 3.7 3 0 0 3 3 3 0 Complement Clr-like EGF-like C2 PF00168.30 KFQ97154.1 - 1.8e-42 143.8 0.0 2.3e-20 72.8 0.0 2.3 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.16 KFQ97154.1 - 1.8e-23 83.0 7.0 3.6e-23 82.0 7.0 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger Prok-RING_4 PF14447.6 KFQ97154.1 - 0.11 12.4 8.1 0.28 11.1 8.1 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFQ97154.1 - 0.36 10.7 9.4 0.7 9.8 9.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KFQ97154.1 - 0.91 9.7 9.0 2 8.6 9.0 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-MIZ PF02891.20 KFQ97154.1 - 2.3 8.0 8.2 4.8 7.0 8.2 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger FYVE PF01363.21 KFQ97154.1 - 2.7 8.2 11.5 8.6 6.6 11.5 1.8 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_5 PF14634.6 KFQ97154.1 - 7.2 6.7 9.2 17 5.5 9.2 1.7 1 1 0 1 1 1 0 zinc-RING finger domain Met_10 PF02475.16 KFQ97155.1 - 2.1e-28 99.5 0.0 2.6e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 KFQ97155.1 - 0.0012 18.4 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KFQ97155.1 - 0.059 14.1 0.0 0.14 12.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KFQ97155.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF3145 PF11343.8 KFQ97155.1 - 0.11 12.0 0.9 0.37 10.3 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3145) Sirohm_synth_M PF14824.6 KFQ97155.1 - 6.4 6.3 7.6 1.5 8.4 0.1 2.9 3 0 0 3 3 3 0 Sirohaem biosynthesis protein central NAD_binding_6 PF08030.12 KFQ97156.1 - 3.7e-31 108.4 0.0 7.6e-31 107.3 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KFQ97156.1 - 5.6e-24 84.7 7.4 1.5e-23 83.2 7.4 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFQ97156.1 - 1.5e-22 79.8 0.0 2.6e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.24 KFQ97156.1 - 0.0021 18.3 0.0 0.0039 17.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KFQ97156.1 - 0.0096 16.6 0.0 0.054 14.1 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain XK-related PF09815.9 KFQ97157.1 - 6e-84 282.0 22.8 6.7e-84 281.8 22.8 1.0 1 0 0 1 1 1 1 XK-related protein NrsF PF06532.11 KFQ97157.1 - 0.097 12.4 0.0 0.097 12.4 0.0 2.9 2 1 1 3 3 3 0 Negative regulator of sigma F PhoLip_ATPase_C PF16212.5 KFQ97158.1 - 1.3e-73 247.8 32.9 1.3e-73 247.8 32.9 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFQ97158.1 - 4.5e-23 80.7 0.3 4.5e-23 80.7 0.3 2.6 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 KFQ97158.1 - 4.9e-11 42.5 0.0 4.9e-11 42.5 0.0 3.0 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KFQ97158.1 - 1.7e-10 40.8 0.0 9.6e-10 38.4 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFQ97158.1 - 3.5e-08 34.0 3.9 0.00011 22.6 3.5 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF63 PF01889.17 KFQ97158.1 - 0.0057 16.9 5.8 0.015 15.5 5.8 1.7 1 0 0 1 1 1 1 Membrane protein of unknown function DUF63 Hydrolase_3 PF08282.12 KFQ97158.1 - 0.0059 16.4 0.1 0.5 10.1 0.0 3.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase VPS13_mid_rpt PF16910.5 KFQ97158.1 - 0.13 11.7 0.3 0.25 10.7 0.3 1.4 1 0 0 1 1 1 0 Repeating coiled region of VPS13 RhoGEF PF00621.20 KFQ97159.1 - 6.9e-36 124.2 0.5 6.9e-36 124.2 0.5 2.6 2 0 0 2 2 2 1 RhoGEF domain CRAL_TRIO_2 PF13716.6 KFQ97159.1 - 9.6e-08 32.3 0.0 2.7e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PH PF00169.29 KFQ97159.1 - 1.4e-06 28.8 0.2 3.2e-06 27.6 0.2 1.6 1 0 0 1 1 1 1 PH domain Spectrin PF00435.21 KFQ97159.1 - 0.0091 16.5 1.5 0.0091 16.5 1.5 4.7 5 1 0 5 5 5 2 Spectrin repeat PH_10 PF15411.6 KFQ97159.1 - 0.066 13.5 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain CRAL_TRIO PF00650.20 KFQ97159.1 - 0.087 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 CRAL/TRIO domain FGF PF00167.18 KFQ97160.1 - 6.4e-44 149.0 0.4 8.2e-44 148.7 0.4 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.13 KFQ97160.1 - 0.00018 21.7 0.1 0.0017 18.6 0.0 2.0 1 1 1 2 2 2 1 Fascin domain TGF_beta_GS PF08515.12 KFQ97160.1 - 0.096 12.2 0.5 0.2 11.2 0.5 1.5 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif zf_ZIC PF18366.1 KFQ97161.1 - 1.4e-27 95.6 8.8 4.8e-27 93.8 0.5 3.7 3 0 0 3 3 3 1 Zic proteins zinc finger domain zf-C2H2 PF00096.26 KFQ97161.1 - 4.5e-22 77.2 31.6 3e-06 27.4 3.0 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ97161.1 - 3.4e-14 52.5 44.5 8.7e-07 29.1 0.3 5.8 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFQ97161.1 - 1.3e-07 31.7 13.6 0.0057 16.9 0.2 5.0 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KFQ97161.1 - 1.1e-06 28.9 48.7 0.0013 19.4 1.9 6.2 6 0 0 6 6 6 5 C2H2-type zinc finger zf-met PF12874.7 KFQ97161.1 - 0.00023 21.4 1.0 0.00023 21.4 1.0 4.2 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFQ97161.1 - 0.0011 18.9 14.0 0.0011 18.9 1.8 4.1 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFQ97161.1 - 0.006 16.8 14.0 0.053 13.8 2.3 3.5 2 1 2 4 4 4 3 C2H2-type zinc ribbon Zf_RING PF16744.5 KFQ97161.1 - 0.12 12.6 1.0 0.28 11.3 0.1 2.0 2 0 0 2 2 2 0 KIAA1045 RING finger CH_2 PF06294.11 KFQ97161.1 - 0.22 11.7 0.0 0.54 10.4 0.0 1.6 1 0 0 1 1 1 0 CH-like domain in sperm protein EMP70 PF02990.16 KFQ97163.1 - 2.5e-197 656.7 14.2 3.2e-197 656.3 14.2 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 RBM1CTR PF08081.11 KFQ97164.1 - 2.6e-21 75.4 18.8 2.6e-21 75.4 18.8 10.0 6 1 2 8 8 8 2 RBM1CTR (NUC064) family RhoGEF67_u2 PF16614.5 KFQ97165.1 - 1.6e-53 179.3 1.3 1.6e-53 179.3 1.3 2.5 2 0 0 2 2 2 1 Unstructured region two on RhoGEF 6 and 7 betaPIX_CC PF16523.5 KFQ97165.1 - 1.3e-37 127.5 8.1 1.3e-37 127.5 8.1 3.4 4 0 0 4 4 4 1 betaPIX coiled coil RhoGEF PF00621.20 KFQ97165.1 - 2.1e-32 112.8 1.4 2.1e-32 112.8 1.4 2.3 2 0 0 2 2 2 1 RhoGEF domain SH3_9 PF14604.6 KFQ97165.1 - 2.1e-17 62.7 0.1 4.2e-17 61.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain CH PF00307.31 KFQ97165.1 - 6.5e-17 61.7 0.0 1.8e-16 60.3 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain SH3_2 PF07653.17 KFQ97165.1 - 2.6e-16 59.0 0.4 5.2e-16 58.1 0.4 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFQ97165.1 - 1.6e-14 53.2 0.3 3e-14 52.3 0.3 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 KFQ97165.1 - 1.1e-09 38.8 0.0 3.2e-09 37.2 0.0 1.8 2 0 0 2 2 1 1 PH domain RhoGEF67_u1 PF16615.5 KFQ97165.1 - 1.4e-09 38.3 4.7 1.4e-09 38.3 4.7 2.9 2 0 0 2 2 2 1 Unstructured region one on RhoGEF 6 and 7 CAMSAP_CH PF11971.8 KFQ97165.1 - 0.002 17.9 0.0 0.0062 16.3 0.0 1.8 1 0 0 1 1 1 1 CAMSAP CH domain Nmad5 PF18757.1 KFQ97165.1 - 0.088 13.0 5.1 0.98 9.6 3.1 2.8 2 1 0 2 2 2 0 Nucleotide modification associated domain 5 DUF4559 PF15112.6 KFQ97165.1 - 0.99 9.0 7.9 0.46 10.1 0.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4559) CENP-Q PF13094.6 KFQ97165.1 - 1.3 9.2 18.3 0.06 13.5 6.7 3.3 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit She9_MDM33 PF05546.11 KFQ97165.1 - 2.1 8.1 8.1 4.4 7.1 0.3 2.4 2 0 0 2 2 2 0 She9 / Mdm33 family RPW8 PF05659.11 KFQ97165.1 - 2.4 7.8 11.6 1.7 8.3 0.6 2.9 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 SKA1 PF07160.12 KFQ97165.1 - 2.7 7.8 11.2 0.2 11.5 3.0 3.0 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 DUF724 PF05266.14 KFQ97165.1 - 6.6 6.5 10.5 2.8 7.7 4.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Nsp1_C PF05064.13 KFQ97165.1 - 7.2 6.5 12.3 0.27 11.1 1.7 3.6 4 1 0 4 4 4 0 Nsp1-like C-terminal region OmpH PF03938.14 KFQ97165.1 - 7.4 6.9 11.3 5.3 7.4 0.3 3.3 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) TNF PF00229.18 KFQ97166.1 - 4.1e-32 110.8 0.2 7.4e-32 110.0 0.2 1.4 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family C1q PF00386.21 KFQ97166.1 - 0.00091 19.4 0.6 0.0041 17.3 0.2 2.3 2 1 0 2 2 2 1 C1q domain DUF2244 PF10003.9 KFQ97166.1 - 0.11 12.2 0.3 0.4 10.3 0.3 1.8 1 1 0 1 1 1 0 Integral membrane protein (DUF2244) Vg_Tdu PF07545.14 KFQ97167.1 - 8.7e-20 70.2 0.3 1.7e-19 69.2 0.3 1.5 1 0 0 1 1 1 1 Vestigial/Tondu family RRM_1 PF00076.22 KFQ97168.1 - 3.6e-16 58.7 0.0 1.3e-06 28.2 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFQ97168.1 - 0.011 15.8 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif RRM_occluded PF16842.5 KFQ97168.1 - 0.093 12.6 0.0 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF1998 PF09369.10 KFQ97168.1 - 0.15 12.9 0.0 1.4 9.8 0.0 2.5 3 1 0 3 3 3 0 Domain of unknown function (DUF1998) 7tm_1 PF00001.21 KFQ97169.1 - 8.6e-58 195.7 14.9 1.3e-57 195.2 14.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ97169.1 - 2.7e-11 43.3 14.5 4.3e-11 42.7 14.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 KFQ97169.1 - 2.7e-08 33.5 14.7 3.5e-08 33.2 14.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 KFQ97169.1 - 1.1e-06 28.5 10.9 1.1e-06 28.5 10.9 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx TAS2R PF05296.13 KFQ97169.1 - 0.00073 18.7 4.2 0.00073 18.7 4.2 2.0 2 0 0 2 2 2 1 Taste receptor protein (TAS2R) Gaa1 PF04114.14 KFQ97169.1 - 2.4 7.1 9.4 0.27 10.2 1.6 2.0 2 0 0 2 2 2 0 Gaa1-like, GPI transamidase component 7tm_2 PF00002.24 KFQ97170.1 - 7.1e-48 163.0 22.7 9.5e-48 162.6 22.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 KFQ97170.1 - 8.3e-16 58.3 5.1 1.5e-15 57.4 5.1 1.5 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif NDUF_B12 PF08122.12 KFQ97170.1 - 0.2 11.8 2.9 16 5.6 0.0 3.4 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family LIM PF00412.22 KFQ97171.1 - 1.5e-47 159.6 72.8 6.3e-13 48.7 10.2 5.1 5 0 0 5 5 5 5 LIM domain zf-RING_6 PF14835.6 KFQ97171.1 - 0.0023 17.8 2.4 0.0023 17.8 2.4 5.5 5 1 0 5 5 5 1 zf-RING of BARD1-type protein Ureidogly_lyase PF04115.12 KFQ97171.1 - 0.026 14.3 0.1 2.2 8.0 0.0 2.9 1 1 1 2 2 2 0 Ureidoglycolate lyase Sgf11 PF08209.11 KFQ97171.1 - 0.036 13.6 0.4 0.036 13.6 0.4 9.2 10 2 2 12 12 12 0 Sgf11 (transcriptional regulation protein) DUF4476 PF14771.6 KFQ97171.1 - 0.21 11.9 0.5 1.2 9.4 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4476) FRD2 PF03197.13 KFQ97171.1 - 6.9 7.0 8.4 1.7 9.0 0.4 3.2 3 1 1 4 4 4 0 Bacteriophage FRD2 protein Na_H_Exchanger PF00999.21 KFQ97172.1 - 8.8e-78 261.7 35.8 4.6e-77 259.4 35.8 2.0 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family MMgT PF10270.9 KFQ97173.1 - 1.1e-06 28.9 0.0 1.6e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Membrane magnesium transporter Motile_Sperm PF00635.26 KFQ97174.1 - 8.4e-18 64.2 0.2 1.3e-17 63.6 0.1 1.4 1 1 0 1 1 1 1 MSP (Major sperm protein) domain Alpha_Helical PF18489.1 KFQ97174.1 - 0.08 13.1 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Alpha helical domain Pribosyltran PF00156.27 KFQ97177.1 - 7.2e-15 54.9 0.0 1.2e-14 54.1 0.0 1.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain zf-HC5HC2H PF13771.6 KFQ97178.1 - 1.6e-34 118.0 31.6 6.4e-18 64.8 9.4 3.6 4 0 0 4 4 4 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFQ97178.1 - 8e-14 51.7 29.3 3.7e-07 30.3 13.1 2.9 2 2 1 3 3 3 2 PHD-zinc-finger like domain zf-ANAPC11 PF12861.7 KFQ97178.1 - 0.32 11.1 14.4 3.7 7.7 0.5 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger Glypican PF01153.19 KFQ97179.1 - 2.8e-227 756.0 6.4 3.3e-227 755.8 6.4 1.0 1 0 0 1 1 1 1 Glypican DUF5082 PF16888.5 KFQ97179.1 - 0.0034 17.6 0.3 0.027 14.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) DUF1910 PF08928.10 KFQ97179.1 - 0.013 15.4 0.5 0.2 11.6 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) Fz PF01392.22 KFQ97179.1 - 0.078 13.6 1.9 0.12 13.0 0.1 2.2 2 0 0 2 2 2 0 Fz domain Sulfotransfer_2 PF03567.14 KFQ97180.1 - 1.5e-18 67.7 0.2 1.5e-18 67.6 0.2 1.0 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFQ97181.1 - 1.6e-48 165.8 1.1 1.6e-48 165.8 1.1 1.5 2 0 0 2 2 2 1 Sulfotransferase family Topoisom_I_N PF02919.15 KFQ97181.1 - 0.27 10.7 5.5 0.42 10.1 5.5 1.3 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment zf-CCCH PF00642.24 KFQ97182.1 - 1.7e-13 50.1 17.3 0.00021 21.1 0.4 4.6 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KFQ97182.1 - 7.1e-06 26.2 12.1 0.012 15.8 0.8 2.7 2 1 0 2 2 2 2 Zinc-finger containing family Torus PF16131.5 KFQ97182.1 - 7.4e-06 26.6 18.9 0.021 15.5 0.2 4.3 2 2 2 4 4 4 4 Torus domain zf-CCCH_2 PF14608.6 KFQ97182.1 - 1.1e-05 25.7 25.3 0.36 11.4 0.8 4.4 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 KFQ97182.1 - 2.7e-05 23.8 2.1 2.7e-05 23.8 2.1 4.8 4 2 0 4 4 4 3 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFQ97182.1 - 0.00045 20.2 32.1 0.015 15.3 3.2 6.7 4 4 0 4 4 4 2 Zinc finger domain DUF1936 PF09151.10 KFQ97182.1 - 0.34 10.9 3.8 8 6.5 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) Ras PF00071.22 KFQ97183.1 - 2.6e-56 189.7 0.0 3e-56 189.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ97183.1 - 2.7e-20 72.8 0.0 3.8e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ97183.1 - 1.4e-09 37.6 0.0 1.5e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFQ97183.1 - 7.9e-07 29.1 0.2 0.0015 18.5 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFQ97183.1 - 2e-05 24.2 0.1 0.00012 21.7 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFQ97183.1 - 0.00033 20.7 0.0 0.00049 20.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFQ97183.1 - 0.0044 16.5 0.2 0.018 14.6 0.2 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 KFQ97183.1 - 0.019 15.0 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain TPP_enzyme_M PF00205.22 KFQ97183.1 - 0.021 14.6 0.0 0.05 13.3 0.0 1.6 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain MeaB PF03308.16 KFQ97183.1 - 0.096 11.6 0.1 1.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FERM_C PF09380.10 KFQ97184.1 - 8.9e-26 90.1 0.4 1.9e-25 89.1 0.4 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 KFQ97184.1 - 6.4e-15 55.6 0.2 1.2e-14 54.8 0.2 1.4 1 0 0 1 1 1 1 FERM central domain FA PF08736.11 KFQ97184.1 - 1.1e-12 47.8 4.6 2.2e-12 46.9 2.3 2.3 2 0 0 2 2 2 1 FERM adjacent (FA) FERM_N PF09379.10 KFQ97184.1 - 2e-09 37.3 0.0 5.5e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 FERM N-terminal domain Pkinase PF00069.25 KFQ97186.1 - 2.6e-72 243.3 0.0 3.1e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ97186.1 - 4.4e-54 183.5 0.0 5.5e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFQ97186.1 - 2.7e-05 23.1 0.0 4.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFQ97186.1 - 0.0036 16.7 0.1 0.039 13.3 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFQ97186.1 - 0.013 14.5 0.1 0.54 9.1 0.1 2.1 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KFQ97186.1 - 0.033 14.1 0.0 5.2 6.9 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KFQ97186.1 - 0.065 12.6 0.1 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ssDNA_DBD PF18333.1 KFQ97186.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Non-canonical single-stranded DNA-binding domain IL6Ra-bind PF09240.10 KFQ97187.1 - 3.6e-19 69.0 0.4 9.1e-19 67.7 0.4 1.7 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.10 KFQ97187.1 - 8.7e-07 29.1 2.1 9.7e-07 29.0 0.4 1.9 2 0 0 2 2 2 1 Erythropoietin receptor, ligand binding fn3 PF00041.21 KFQ97187.1 - 2.4e-05 24.6 0.1 0.0053 17.1 0.0 2.9 2 1 0 2 2 2 1 Fibronectin type III domain Tissue_fac PF01108.17 KFQ97187.1 - 3.8e-05 23.5 1.7 0.44 10.4 0.3 3.3 3 0 0 3 3 3 2 Tissue factor LIFR_N PF18207.1 KFQ97187.1 - 0.083 13.3 0.8 0.22 11.9 0.8 1.8 1 0 0 1 1 1 0 Leukemia inhibitory factor receptor N-terminal domain IL2RB_N1 PF18707.1 KFQ97187.1 - 0.11 13.0 0.6 0.11 13.0 0.6 2.2 3 0 0 3 3 3 0 Interleukin-2 receptor subunit beta N-terminal domain 1 DHR-2 PF06920.13 KFQ97188.1 - 2e-203 676.8 9.5 2e-203 676.8 9.5 1.8 2 0 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 KFQ97188.1 - 3.1e-57 193.5 0.7 4.8e-56 189.7 0.2 2.5 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 KFQ97188.1 - 3.5e-42 143.3 1.5 7e-42 142.4 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3398) PH PF00169.29 KFQ97188.1 - 1.5e-11 44.8 0.6 7.6e-11 42.5 0.6 2.4 1 0 0 1 1 1 1 PH domain PRR22 PF15776.5 KFQ97189.1 - 4.7e-10 39.4 8.9 2.6e-07 30.4 3.1 2.3 1 1 1 2 2 2 2 Proline-rich protein family 22 WD40 PF00400.32 KFQ97190.1 - 1.1e-24 86.2 9.1 0.00022 22.0 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ97190.1 - 7.2e-06 26.2 0.4 1.7 9.0 0.0 4.8 3 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DAO_C PF16901.5 KFQ97190.1 - 0.047 13.6 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase BBS2_Mid PF14783.6 KFQ97190.1 - 0.1 12.7 0.1 4.9 7.2 0.0 3.4 2 2 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Kelch_1 PF01344.25 KFQ97191.1 - 3.7e-56 186.5 8.5 1.2e-10 40.8 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFQ97191.1 - 1.4e-35 120.4 6.3 1e-07 32.0 0.0 7.1 1 1 5 6 6 6 6 Kelch motif BACK PF07707.15 KFQ97191.1 - 3.1e-27 94.7 0.0 6.9e-27 93.6 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 KFQ97191.1 - 3.2e-24 85.3 0.2 1.2e-23 83.4 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 KFQ97191.1 - 7.2e-24 82.8 5.3 3.7e-05 23.5 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KFQ97191.1 - 1.4e-23 82.6 4.0 3.3e-06 27.2 0.0 6.7 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KFQ97191.1 - 1.1e-17 63.8 0.9 0.0015 18.5 0.0 5.6 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KFQ97191.1 - 9.6e-11 41.4 13.0 0.0052 16.7 0.6 5.7 5 0 0 5 5 5 4 Kelch motif PQQ_3 PF13570.6 KFQ97191.1 - 0.0062 17.0 5.7 9.5 6.9 0.0 5.0 6 0 0 6 6 6 1 PQQ-like domain DUF1075 PF06388.11 KFQ97192.1 - 9.3e-38 129.0 0.1 1.1e-37 128.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1075) Pho88 PF10032.9 KFQ97192.1 - 0.14 11.4 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Phosphate transport (Pho88) SNF PF00209.18 KFQ97193.1 - 4.7e-197 655.8 40.9 5.9e-197 655.5 40.9 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family LRR_8 PF13855.6 KFQ97194.1 - 3.5e-30 103.5 37.9 2.5e-13 49.6 8.2 4.1 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFQ97194.1 - 1.7e-16 60.1 51.4 7.3e-07 29.4 3.8 4.8 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFQ97194.1 - 1.1e-11 44.8 2.4 3.2e-09 36.8 1.1 2.1 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFQ97194.1 - 4.6e-08 32.5 34.8 0.28 11.9 2.7 7.3 7 0 0 7 7 7 6 Leucine Rich Repeat LRR_9 PF14580.6 KFQ97194.1 - 1.6e-05 24.5 6.9 0.0044 16.6 0.7 2.6 1 1 2 3 3 3 3 Leucine-rich repeat LRRNT PF01462.18 KFQ97194.1 - 0.066 12.9 1.1 0.066 12.9 1.1 2.0 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 KFQ97194.1 - 2 8.7 0.0 2 8.7 0.0 7.1 7 1 0 7 7 7 0 Leucine Rich repeat CH PF00307.31 KFQ97195.1 - 2.5e-92 304.4 1.8 1.2e-25 89.8 0.1 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 KFQ97195.1 - 2.6e-09 37.4 0.5 1.2e-08 35.3 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFQ97195.1 - 2.4e-07 29.8 2.1 4e-05 22.9 0.5 2.9 2 0 0 2 2 2 2 EF hand CAMSAP_CH PF11971.8 KFQ97195.1 - 9.9e-06 25.3 0.0 0.00035 20.3 0.0 2.8 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_5 PF13202.6 KFQ97195.1 - 0.00016 21.0 4.7 0.0007 19.0 0.1 3.8 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.6 KFQ97195.1 - 0.0076 16.1 3.4 0.036 14.0 0.1 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 KFQ97195.1 - 0.031 14.1 0.4 0.19 11.6 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain pair FYTT PF07078.11 KFQ97196.1 - 0.00024 20.5 5.6 0.00028 20.3 5.6 1.0 1 0 0 1 1 1 1 Forty-two-three protein LRR_8 PF13855.6 KFQ97197.1 - 2.7e-25 87.9 8.5 2.9e-10 39.8 1.3 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFQ97197.1 - 1.3e-15 57.2 16.8 0.00043 20.6 4.0 5.4 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) CH PF00307.31 KFQ97197.1 - 4.2e-10 39.8 0.0 8.6e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain LRR_1 PF00560.33 KFQ97197.1 - 8.9e-05 22.5 17.3 2.8 8.8 0.3 7.7 7 1 0 7 7 7 2 Leucine Rich Repeat CDC24 PF06395.11 KFQ97197.1 - 0.0091 16.2 0.0 0.023 14.9 0.0 1.7 1 0 0 1 1 1 1 CDC24 Calponin LRR_6 PF13516.6 KFQ97197.1 - 0.013 15.5 17.7 15 6.0 0.4 6.3 6 0 0 6 6 6 0 Leucine Rich repeat CAMSAP_CH PF11971.8 KFQ97197.1 - 0.032 14.1 0.1 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 CAMSAP CH domain LRR_9 PF14580.6 KFQ97197.1 - 0.68 9.4 7.9 3.9 7.0 1.3 2.8 1 1 1 2 2 2 0 Leucine-rich repeat DUF4763 PF15960.5 KFQ97197.1 - 3.5 6.9 17.9 0.1 11.9 8.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4763) IL6Ra-bind PF09240.10 KFQ97198.1 - 3.9e-28 97.7 0.4 1.1e-27 96.2 0.1 2.0 2 0 0 2 2 2 1 Interleukin-6 receptor alpha chain, binding fn3 PF00041.21 KFQ97198.1 - 7.9e-09 35.7 0.1 0.0021 18.4 0.1 3.3 3 0 0 3 3 3 2 Fibronectin type III domain EpoR_lig-bind PF09067.10 KFQ97198.1 - 3.4e-05 24.0 0.3 9.4e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Erythropoietin receptor, ligand binding Il13Ra_Ig PF18001.1 KFQ97198.1 - 0.061 13.4 1.8 2.8 8.1 0.1 2.9 3 0 0 3 3 3 0 Interleukin-13 receptor subunit alpha Ig-like domain 7tm_1 PF00001.21 KFQ97199.1 - 4.1e-65 219.7 13.5 5.5e-65 219.3 13.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ97199.1 - 1.2e-12 47.8 14.4 3.2e-12 46.4 14.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFQ97199.1 - 1.3e-05 24.9 12.4 1.3e-05 24.9 12.4 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFQ97199.1 - 0.00029 20.7 9.3 0.00029 20.7 9.3 2.3 2 1 1 3 3 3 1 Olfactory receptor Pox_P21 PF05313.12 KFQ97199.1 - 0.044 13.4 0.7 0.044 13.4 0.7 3.0 3 0 0 3 3 3 0 Poxvirus P21 membrane protein RseC_MucC PF04246.12 KFQ97199.1 - 8.1 6.4 8.1 0.27 11.2 0.3 2.5 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC GDPD PF03009.17 KFQ97200.1 - 6.7e-21 75.2 0.0 2.7e-20 73.2 0.0 1.8 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family 7TMR-HDED PF07697.11 KFQ97200.1 - 0.19 11.8 0.3 0.25 11.4 0.3 1.2 1 0 0 1 1 1 0 7TM-HD extracellular Guanylate_kin PF00625.21 KFQ97201.1 - 7.5e-61 205.0 0.1 1.1e-60 204.4 0.1 1.3 1 0 0 1 1 1 1 Guanylate kinase PDZ PF00595.24 KFQ97201.1 - 5.9e-54 180.4 11.1 7.7e-22 77.5 0.5 3.4 3 0 0 3 3 3 3 PDZ domain PDZ_assoc PF10600.9 KFQ97201.1 - 4.9e-30 104.2 3.6 1.3e-29 102.8 3.6 1.8 1 0 0 1 1 1 1 PDZ-associated domain of NMDA receptors PDZ_6 PF17820.1 KFQ97201.1 - 1e-20 73.3 4.5 6.2e-07 29.2 0.1 3.6 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 KFQ97201.1 - 9.4e-14 51.5 2.9 8.3e-05 22.8 0.2 3.5 3 0 0 3 3 3 3 PDZ domain SH3_1 PF00018.28 KFQ97201.1 - 2e-08 33.7 0.0 4.3e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFQ97201.1 - 1.8e-07 30.7 0.0 4.7e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFQ97201.1 - 0.0024 17.7 0.1 0.0099 15.7 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SPO22 PF08631.10 KFQ97202.1 - 2e-82 276.8 25.7 4.2e-78 262.6 2.8 3.2 3 0 0 3 3 3 3 Meiosis protein SPO22/ZIP4 like TPR_2 PF07719.17 KFQ97202.1 - 7.8e-06 25.6 8.7 0.011 15.8 0.1 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ97202.1 - 2.6e-05 24.4 6.1 1.1 9.6 0.0 5.8 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ97202.1 - 0.00014 22.3 0.5 0.016 15.7 0.0 4.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ97202.1 - 0.0028 17.4 8.4 0.17 11.7 0.1 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat ptaRNA1_toxin PF12703.7 KFQ97202.1 - 0.066 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Toxin of toxin-antitoxin type 1 system DUF493 PF04359.14 KFQ97202.1 - 0.085 13.4 0.1 0.37 11.4 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF493) TPR_8 PF13181.6 KFQ97202.1 - 0.17 12.2 0.6 3.8 8.0 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ97202.1 - 0.59 11.1 3.9 10 7.2 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat RRM_1 PF00076.22 KFQ97203.1 - 1.5e-18 66.4 0.0 1.9e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFQ97203.1 - 0.037 13.9 0.0 0.093 12.6 0.0 1.6 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_5 PF13893.6 KFQ97203.1 - 0.16 11.6 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AA_permease_2 PF13520.6 KFQ97204.1 - 1.8e-50 172.0 20.9 1.8e-50 172.0 20.9 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 KFQ97204.1 - 1.2e-35 123.1 23.5 1.2e-35 123.1 23.5 2.3 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 KFQ97204.1 - 1e-22 79.9 8.0 1e-22 79.9 8.0 4.4 4 0 0 4 4 4 1 C-terminus of AA_permease Trep_Strep PF09605.10 KFQ97204.1 - 0.0025 17.8 6.3 0.0025 17.8 6.3 5.2 4 2 1 5 5 5 1 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF2678 PF10856.8 KFQ97204.1 - 3.7 7.5 10.9 2.2 8.2 3.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2678) PX PF00787.24 KFQ97205.1 - 7.7e-22 77.4 0.2 8.5e-22 77.3 0.2 1.1 1 0 0 1 1 1 1 PX domain RdRP_1 PF00680.20 KFQ97205.1 - 0.12 10.8 0.0 0.13 10.8 0.0 1.0 1 0 0 1 1 1 0 RNA dependent RNA polymerase PA26 PF04636.13 KFQ97206.1 - 3.9e-182 606.1 0.0 4.4e-182 605.9 0.0 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) CMD PF02627.20 KFQ97206.1 - 0.0033 17.4 0.0 0.01 15.9 0.0 1.9 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Leptin PF02024.15 KFQ97206.1 - 0.015 15.1 0.0 0.27 11.0 0.0 2.3 2 0 0 2 2 2 0 Leptin IL6Ra-bind PF09240.10 KFQ97207.1 - 2.8e-20 72.6 0.1 5.1e-20 71.7 0.1 1.5 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.10 KFQ97207.1 - 2e-07 31.2 0.2 4.8e-07 29.9 0.2 1.6 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding fn3 PF00041.21 KFQ97207.1 - 8e-06 26.1 1.3 8e-06 26.1 1.3 2.2 2 0 0 2 2 2 1 Fibronectin type III domain COesterase PF00135.28 KFQ97208.1 - 2.5e-190 633.7 0.0 3e-190 633.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFQ97208.1 - 4.9e-05 23.3 0.2 0.00029 20.7 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Connexin PF00029.19 KFQ97209.1 - 8.3e-85 284.3 16.6 2.9e-83 279.2 16.6 2.0 1 1 0 1 1 1 1 Connexin Ninjurin PF04923.12 KFQ97209.1 - 0.11 12.4 1.3 0.37 10.7 0.0 2.4 2 1 0 2 2 2 0 Ninjurin Connexin PF00029.19 KFQ97210.1 - 6.6e-84 281.3 0.0 8.8e-84 280.9 0.0 1.2 1 0 0 1 1 1 1 Connexin zf-FCS PF06467.14 KFQ97211.1 - 7.9e-65 214.5 115.8 7.9e-10 38.5 3.8 10.7 10 0 0 10 10 10 10 MYM-type Zinc finger with FCS sequence motif DUF3504 PF12012.8 KFQ97211.1 - 9.1e-64 214.3 0.8 9.1e-64 214.3 0.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3504) Arc_trans_TRASH PF08394.10 KFQ97211.1 - 0.00013 22.2 7.4 0.00013 22.2 7.4 8.7 10 2 0 10 10 10 1 Archaeal TRASH domain YHS PF04945.13 KFQ97211.1 - 0.0018 18.3 50.9 0.18 12.0 0.1 10.1 10 1 0 10 10 10 4 YHS domain NosL PF05573.12 KFQ97211.1 - 0.028 14.7 2.2 11 6.4 0.0 4.0 3 1 1 4 4 4 0 NosL CAP_N PF01213.19 KFQ97211.1 - 0.73 9.3 5.1 1.2 8.5 5.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF2733 PF10813.8 KFQ97211.1 - 2.4 8.0 4.9 1.6 8.6 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) RRM_1 PF00076.22 KFQ97212.1 - 8.9e-32 108.7 0.1 8e-16 57.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.11 KFQ97212.1 - 5e-27 93.8 2.0 1.4e-26 92.4 2.0 1.8 1 0 0 1 1 1 1 NOPS (NUC059) domain RRM_7 PF16367.5 KFQ97212.1 - 9.1e-05 22.5 0.0 0.0015 18.6 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 KFQ97212.1 - 0.0078 16.1 0.0 0.03 14.2 0.0 1.9 2 0 0 2 2 2 1 Occluded RNA-recognition motif Lipoprotein_18 PF06804.11 KFQ97212.1 - 0.1 11.6 5.5 0.043 12.9 3.0 1.6 1 1 0 1 1 1 0 NlpB/DapX lipoprotein RRM_5 PF13893.6 KFQ97212.1 - 0.11 12.1 0.0 0.5 10.0 0.0 2.0 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aldedh PF00171.22 KFQ97212.1 - 2.8 6.3 5.1 4 5.8 5.1 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family GvpL_GvpF PF06386.11 KFQ97212.1 - 3.1 7.6 15.9 5 7.0 15.9 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF3523 PF12037.8 KFQ97212.1 - 3.5 6.9 28.8 6.1 6.1 28.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) CHORD PF04968.12 KFQ97213.1 - 1.9e-53 179.0 21.5 4.6e-28 97.7 6.4 2.6 3 0 0 3 3 3 2 CHORD CS PF04969.16 KFQ97213.1 - 6.5e-12 46.3 0.7 1.1e-11 45.6 0.7 1.4 1 0 0 1 1 1 1 CS domain zf-tcix PF14952.6 KFQ97213.1 - 0.013 15.0 1.9 0.49 10.1 0.2 2.6 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding DUF4147 PF13660.6 KFQ97213.1 - 0.2 11.2 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) BTK PF00779.19 KFQ97213.1 - 0.76 9.6 15.9 0.35 10.7 0.4 3.7 4 1 0 4 4 4 0 BTK motif Ras PF00071.22 KFQ97214.1 - 2.1e-56 190.0 0.0 2.5e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ97214.1 - 2.1e-23 82.8 0.0 2.9e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ97214.1 - 7.3e-10 38.6 0.0 9.6e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFQ97214.1 - 0.0072 15.9 0.0 0.04 13.5 0.0 1.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 KFQ97214.1 - 0.097 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF3591 PF12157.8 KFQ97215.1 - 1.1e-163 545.1 0.0 6e-163 542.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 KFQ97215.1 - 7.5e-45 150.9 3.9 4.8e-23 81.0 0.8 2.8 2 0 0 2 2 2 2 Bromodomain TBP-binding PF09247.11 KFQ97215.1 - 1.6e-22 79.5 2.0 4.3e-22 78.1 2.0 1.8 1 0 0 1 1 1 1 TATA box-binding protein binding zf-CCHC_6 PF15288.6 KFQ97215.1 - 4.2e-16 58.5 0.4 1.4e-15 56.9 0.4 1.9 1 0 0 1 1 1 1 Zinc knuckle Glyco_transf_41 PF13844.6 KFQ97216.1 - 1.6e-256 851.2 0.0 2.1e-256 850.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 41 TPR_1 PF00515.28 KFQ97216.1 - 6.8e-98 316.9 27.2 2.5e-10 39.7 0.3 13.5 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ97216.1 - 3.2e-90 295.6 36.3 9.1e-11 41.3 0.4 12.8 3 2 10 13 13 13 12 TPR repeat TPR_2 PF07719.17 KFQ97216.1 - 6.5e-74 238.2 27.7 2.5e-08 33.4 0.4 13.2 13 0 0 13 13 12 11 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ97216.1 - 3.1e-68 221.4 28.8 1.9e-05 24.7 0.1 13.7 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ97216.1 - 1.1e-66 215.5 12.4 1.1e-06 28.4 0.1 13.5 14 0 0 14 14 13 11 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ97216.1 - 3.6e-48 161.7 29.2 2.8e-10 40.3 0.2 9.5 6 2 3 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ97216.1 - 2e-46 152.7 17.0 0.00033 21.2 0.1 12.3 5 3 7 12 12 12 10 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ97216.1 - 1.5e-45 153.5 17.4 2.1e-09 37.9 0.1 7.6 6 1 0 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ97216.1 - 1.3e-43 147.3 20.5 2e-07 31.4 0.6 9.2 4 4 5 9 9 9 9 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ97216.1 - 2.7e-39 130.3 17.3 9.7e-05 22.1 0.1 13.0 13 1 1 14 14 13 9 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ97216.1 - 5.3e-36 121.5 47.3 6.9e-07 28.9 0.4 12.2 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_9 PF13371.6 KFQ97216.1 - 9.8e-18 64.1 14.7 0.00079 19.5 0.4 6.8 5 1 1 7 7 6 5 Tetratricopeptide repeat TPR_6 PF13174.6 KFQ97216.1 - 2e-15 56.3 14.6 0.47 11.2 0.0 10.4 11 0 0 11 11 9 2 Tetratricopeptide repeat NARP1 PF12569.8 KFQ97216.1 - 1.5e-14 53.9 4.9 0.0013 17.7 0.0 5.7 1 1 5 6 6 6 3 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 KFQ97216.1 - 5.9e-14 51.2 9.7 1.4 9.7 0.2 9.3 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFQ97216.1 - 2.4e-12 46.9 12.7 0.00029 20.3 0.1 4.8 1 1 2 4 4 4 4 MalT-like TPR region TPR_15 PF13429.6 KFQ97216.1 - 3.5e-10 39.6 8.0 4.7e-06 26.0 0.8 4.9 1 1 3 5 5 5 2 Tetratricopeptide repeat FAT PF02259.23 KFQ97216.1 - 5.3e-08 32.5 0.1 0.88 8.7 0.0 5.7 2 2 1 4 4 4 2 FAT domain MIT PF04212.18 KFQ97216.1 - 5.1e-07 29.7 22.0 0.11 12.6 0.1 8.5 7 1 2 9 9 8 2 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 KFQ97216.1 - 2.8e-06 27.2 1.5 1.2 9.2 0.0 5.7 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_21 PF09976.9 KFQ97216.1 - 7.7e-06 25.7 10.8 0.17 11.6 0.0 5.2 3 2 2 5 5 5 3 Tetratricopeptide repeat-like domain Wzy_C_2 PF11846.8 KFQ97216.1 - 7.6e-05 22.7 12.3 0.0083 16.1 0.2 4.6 5 0 0 5 5 4 1 Virulence factor membrane-bound polymerase, C-terminal SNAP PF14938.6 KFQ97216.1 - 0.00017 21.1 15.0 0.034 13.6 2.4 4.7 1 1 2 4 4 4 2 Soluble NSF attachment protein, SNAP EST1_DNA_bind PF10373.9 KFQ97216.1 - 0.00018 21.1 13.9 0.23 10.9 0.1 4.8 5 1 1 6 6 6 2 Est1 DNA/RNA binding domain SHNi-TPR PF10516.9 KFQ97216.1 - 0.0014 18.0 2.5 12 5.4 0.0 5.6 7 0 0 7 7 6 0 SHNi-TPR BTAD PF03704.17 KFQ97216.1 - 0.0016 18.9 16.1 0.31 11.4 0.7 5.7 3 2 4 7 7 7 1 Bacterial transcriptional activator domain ANAPC3 PF12895.7 KFQ97216.1 - 0.011 15.9 16.5 0.056 13.7 0.9 5.5 3 2 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 KFQ97216.1 - 0.017 14.9 6.9 29 4.3 0.1 6.2 4 2 5 9 9 9 0 26S proteasome subunit RPN7 TOM20_plant PF06552.12 KFQ97216.1 - 0.048 13.4 0.3 30 4.3 0.0 4.0 3 2 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 Fis1_TPR_C PF14853.6 KFQ97216.1 - 0.07 13.2 0.5 1 9.5 0.0 3.3 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat Tcf25 PF04910.14 KFQ97216.1 - 0.081 12.0 0.1 0.22 10.6 0.0 1.7 2 0 0 2 2 2 0 Transcriptional repressor TCF25 Mad3_BUB1_I PF08311.12 KFQ97216.1 - 0.13 12.3 8.3 91 3.1 0.1 6.7 6 1 1 8 8 8 0 Mad3/BUB1 homology region 1 DUF627 PF04781.12 KFQ97216.1 - 0.19 11.8 3.9 6 6.9 0.0 4.5 3 1 2 5 5 4 0 Protein of unknown function (DUF627) TPR_20 PF14561.6 KFQ97216.1 - 0.36 11.2 12.9 1.9 8.9 0.2 5.9 4 2 3 7 7 7 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KFQ97216.1 - 1.4 9.4 3.9 12 6.3 0.1 3.3 4 0 0 4 4 2 0 Alkyl sulfatase dimerisation DUF5113 PF17140.4 KFQ97216.1 - 1.7 8.4 11.3 26 4.6 0.2 5.4 3 2 4 7 7 7 0 Domain of unknown function (DUF5113) SprT-like PF10263.9 KFQ97217.1 - 1.1e-07 31.7 0.0 2.1e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 SprT-like family SPRY PF00622.28 KFQ97219.1 - 2.8e-19 69.4 0.0 4.4e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.16 KFQ97219.1 - 8.6e-10 38.8 3.4 1.7e-09 37.8 3.4 1.5 1 0 0 1 1 1 1 SOCS box HELP PF03451.14 KFQ97219.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 HELP motif DUF4462 PF14692.6 KFQ97220.1 - 0.21 11.1 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) His_Phos_2 PF00328.22 KFQ97221.1 - 4.6e-32 111.8 0.0 1.2e-31 110.5 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pkinase_Tyr PF07714.17 KFQ97222.1 - 1.9e-97 325.6 0.0 2.2e-97 325.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ97222.1 - 1.5e-46 159.0 0.0 1.8e-46 158.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.6 KFQ97222.1 - 1e-14 55.2 1.1 1.8e-14 54.3 1.1 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Haspin_kinase PF12330.8 KFQ97222.1 - 0.0048 15.9 0.0 0.0079 15.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFQ97222.1 - 0.021 14.2 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAX PF00292.18 KFQ97223.1 - 4.6e-76 252.7 0.9 6.7e-76 252.2 0.9 1.3 1 0 0 1 1 1 1 'Paired box' domain Pax7 PF12360.8 KFQ97223.1 - 1.9e-25 88.8 6.8 3.7e-25 87.9 6.8 1.5 1 0 0 1 1 1 1 Paired box protein 7 Homeodomain PF00046.29 KFQ97223.1 - 7.9e-23 80.1 6.9 1.3e-22 79.3 6.9 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ97223.1 - 0.00033 20.5 1.4 0.00056 19.8 0.7 1.8 2 0 0 2 2 2 1 Homeobox KN domain HTH_23 PF13384.6 KFQ97223.1 - 0.00036 20.3 2.9 0.0012 18.6 0.1 2.5 3 0 0 3 3 3 1 Homeodomain-like domain HTH_Tnp_IS1 PF12759.7 KFQ97223.1 - 0.15 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 InsA C-terminal domain PAP2 PF01569.21 KFQ97224.1 - 6.2e-16 58.4 3.6 6.2e-16 58.4 3.6 2.2 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KFQ97224.1 - 1.9e-06 27.7 2.7 4.7e-06 26.4 2.7 1.8 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 KFQ97224.1 - 0.13 12.4 1.7 0.59 10.3 0.2 2.4 1 1 1 2 2 2 0 Divergent PAP2 family tRNA_synthFbeta PF17759.1 KFQ97225.1 - 1.2e-51 175.3 0.0 1.6e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B3_4 PF03483.17 KFQ97225.1 - 8.1e-28 97.2 0.1 1.5e-27 96.4 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain PhetRS_B1 PF18262.1 KFQ97225.1 - 7.5e-25 87.0 1.4 3.8e-24 84.7 0.5 2.6 2 1 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B5 PF03484.15 KFQ97225.1 - 1.9e-15 56.9 0.0 1.1e-12 48.1 0.0 3.6 4 0 0 4 4 4 1 tRNA synthetase B5 domain Glyco_hydro_77 PF02446.17 KFQ97225.1 - 0.19 10.6 0.0 0.26 10.1 0.0 1.1 1 0 0 1 1 1 0 4-alpha-glucanotransferase DAGAT PF03982.13 KFQ97226.1 - 3.2e-121 403.8 0.3 3.9e-121 403.5 0.3 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase AMP-binding PF00501.28 KFQ97227.1 - 1.7e-101 339.9 0.2 2.2e-101 339.5 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFQ97227.1 - 4.4e-06 27.6 0.2 1.8e-05 25.6 0.1 2.1 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain ISK_Channel PF02060.15 KFQ97228.1 - 9.4e-10 38.3 0.2 1.2e-09 37.9 0.2 1.3 1 0 0 1 1 1 1 Slow voltage-gated potassium channel Granin PF01271.17 KFQ97229.1 - 5e-124 415.4 36.6 5.6e-124 415.2 36.6 1.0 1 0 0 1 1 1 1 Granin (chromogranin or secretogranin) IF2_N PF04760.15 KFQ97229.1 - 0.0046 16.7 1.4 1.6 8.6 0.2 3.3 2 0 0 2 2 2 2 Translation initiation factor IF-2, N-terminal region Clat_adaptor_s PF01217.20 KFQ97230.1 - 4.5e-59 198.5 3.2 5e-59 198.3 3.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CNOT1_HEAT PF16418.5 KFQ97230.1 - 0.071 13.2 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 HEAT repeat FYVE PF01363.21 KFQ97231.1 - 2.5e-14 53.2 7.6 2.5e-14 53.2 7.6 1.8 2 0 0 2 2 2 1 FYVE zinc finger WD40 PF00400.32 KFQ97231.1 - 4.2e-14 52.7 21.4 4.8e-06 27.2 1.2 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ97231.1 - 3e-05 24.2 0.4 0.22 11.9 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KFQ97231.1 - 0.00032 19.6 1.2 0.98 8.1 0.3 3.4 2 1 0 2 2 2 2 Nup133 N terminal like ELYS-bb PF16687.5 KFQ97231.1 - 0.019 13.6 0.0 0.032 12.9 0.0 1.3 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin IBR PF01485.21 KFQ97231.1 - 0.88 9.8 12.1 4.8 7.5 0.6 2.9 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain FYVE_2 PF02318.16 KFQ97231.1 - 1.2 9.3 8.2 3.8 7.7 8.2 1.9 1 1 0 1 1 1 0 FYVE-type zinc finger Serpin PF00079.20 KFQ97232.1 - 2e-109 366.3 0.0 2.3e-109 366.1 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) FAM124 PF15067.6 KFQ97233.1 - 5.4e-108 360.0 0.1 6e-108 359.9 0.1 1.0 1 0 0 1 1 1 1 FAM124 family TPR_7 PF13176.6 KFQ97233.1 - 0.14 12.2 0.0 0.5 10.5 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Cullin PF00888.22 KFQ97234.1 - 1.3e-227 757.4 9.8 1.5e-227 757.1 9.8 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KFQ97234.1 - 1.7e-27 95.2 1.1 1.7e-27 95.2 1.1 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain Phage_antitermQ PF06530.12 KFQ97234.1 - 0.0087 16.0 0.2 0.05 13.5 0.1 2.4 2 0 0 2 2 2 1 Phage antitermination protein Q RhgB_N PF09284.10 KFQ97234.1 - 0.047 13.2 0.1 0.093 12.2 0.1 1.4 1 0 0 1 1 1 0 Rhamnogalacturonan lyase B, N-terminal Phage_TAC_12 PF12363.8 KFQ97234.1 - 0.055 13.9 0.8 1.1 9.7 0.0 3.3 3 0 0 3 3 3 0 Phage tail assembly chaperone protein, TAC RuvB_C PF05491.13 KFQ97234.1 - 0.83 9.6 2.7 1e+02 2.9 0.0 4.4 4 0 0 4 4 4 0 RuvB C-terminal winged helix domain Glyco_hydro_4C PF11975.8 KFQ97234.1 - 1.6 8.8 8.8 1.8 8.6 1.6 3.6 3 1 0 3 3 3 0 Family 4 glycosyl hydrolase C-terminal domain WAC_Acf1_DNA_bd PF10537.9 KFQ97234.1 - 2.4 8.7 7.1 0.93 10.1 0.3 3.4 3 0 0 3 3 3 0 ATP-utilising chromatin assembly and remodelling N-terminal DHR-2 PF06920.13 KFQ97235.1 - 1.5e-209 697.1 11.0 1.5e-209 697.1 11.0 2.2 2 0 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 KFQ97235.1 - 5.3e-57 192.8 0.4 2.6e-56 190.6 0.2 2.4 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 KFQ97235.1 - 4.9e-36 123.6 1.4 1.5e-35 122.0 1.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) PH PF00169.29 KFQ97235.1 - 3.9e-13 49.8 0.6 2e-12 47.5 0.6 2.4 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KFQ97235.1 - 0.0099 16.2 1.1 0.04 14.3 0.1 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_10 PF15411.6 KFQ97235.1 - 0.025 14.8 0.0 0.083 13.2 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain NYAP_N PF15439.6 KFQ97237.1 - 4.8e-136 454.1 39.0 4.8e-136 454.1 39.0 3.8 2 2 1 3 3 3 1 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter NYAP_C PF15452.6 KFQ97237.1 - 6.2e-42 144.3 14.4 6.2e-42 144.3 14.4 1.8 2 0 0 2 2 2 1 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter HLH PF00010.26 KFQ97240.1 - 3.4e-14 52.5 0.4 5.6e-14 51.8 0.4 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain KAP_NTPase PF07693.14 KFQ97241.1 - 1.9e-108 362.6 0.2 2.7e-108 362.1 0.2 1.2 1 0 0 1 1 1 1 KAP family P-loop domain Ank_2 PF12796.7 KFQ97241.1 - 7.9e-76 250.7 1.8 1.4e-13 51.2 0.0 6.8 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFQ97241.1 - 2.1e-62 206.4 7.4 4.4e-12 46.0 0.2 10.4 2 1 8 10 10 10 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFQ97241.1 - 1.1e-58 194.9 0.1 3.4e-10 40.3 0.0 9.6 4 2 7 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 KFQ97241.1 - 1.2e-55 183.7 1.1 7.4e-07 29.4 0.0 11.8 11 0 0 11 11 11 10 Ankyrin repeat Ank_3 PF13606.6 KFQ97241.1 - 5e-49 158.6 0.5 6.6e-06 26.1 0.0 12.5 12 0 0 12 12 12 9 Ankyrin repeat SAM_1 PF00536.30 KFQ97241.1 - 0.00092 19.6 0.0 0.0044 17.4 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) NACHT PF05729.12 KFQ97241.1 - 0.0016 18.4 0.1 0.19 11.6 0.0 2.9 3 0 0 3 3 3 1 NACHT domain DUF4988 PF16378.5 KFQ97241.1 - 0.075 12.7 0.2 0.53 9.9 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function MgtE PF01769.16 KFQ97241.1 - 1.3 9.5 8.6 2.1 8.7 2.0 2.3 2 0 0 2 2 2 0 Divalent cation transporter MBOAT PF03062.19 KFQ97242.1 - 9.5e-30 104.1 19.7 2.5e-28 99.4 19.7 2.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family ArfGap PF01412.18 KFQ97244.1 - 3.5e-33 114.2 0.6 9.2e-33 112.8 0.0 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 KFQ97244.1 - 1.2e-23 84.1 4.7 2.2e-23 83.2 4.7 1.5 1 0 0 1 1 1 1 BAR domain of APPL family Ank_2 PF12796.7 KFQ97244.1 - 5.3e-19 68.6 4.8 4.4e-10 40.0 0.5 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) PH PF00169.29 KFQ97244.1 - 3.6e-12 46.7 0.6 1.4e-11 44.9 0.4 2.2 2 0 0 2 2 1 1 PH domain SH3_9 PF14604.6 KFQ97244.1 - 8.4e-10 38.4 0.1 1.6e-09 37.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ank_4 PF13637.6 KFQ97244.1 - 3.8e-09 36.9 1.4 4.1e-05 24.0 0.2 3.2 2 1 2 4 4 3 2 Ankyrin repeats (many copies) SH3_1 PF00018.28 KFQ97244.1 - 6.5e-09 35.3 1.3 1.5e-08 34.1 0.2 2.2 2 0 0 2 2 2 1 SH3 domain Ank PF00023.30 KFQ97244.1 - 1.7e-08 34.5 0.7 0.0012 19.2 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat SH3_2 PF07653.17 KFQ97244.1 - 1.5e-07 31.0 0.1 3.7e-07 29.7 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain Ank_3 PF13606.6 KFQ97244.1 - 1.2e-06 28.4 0.4 0.1 13.2 0.0 3.9 4 0 0 4 4 3 2 Ankyrin repeat Ank_5 PF13857.6 KFQ97244.1 - 6e-06 26.4 0.1 0.00011 22.4 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) BAR PF03114.18 KFQ97244.1 - 1.5e-05 24.8 1.5 2.7e-05 23.9 1.5 1.4 1 0 0 1 1 1 1 BAR domain PH_9 PF15410.6 KFQ97244.1 - 0.0063 16.9 0.2 1.6 9.1 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 KFQ97244.1 - 0.032 14.1 0.0 0.082 12.7 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain ICAP-1_inte_bdg PF10480.9 KFQ97245.1 - 2.3e-128 426.1 6.9 2.6e-128 425.9 6.9 1.0 1 0 0 1 1 1 1 Beta-1 integrin binding protein PID PF00640.23 KFQ97245.1 - 6.7e-06 26.2 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) YCII PF03795.14 KFQ97245.1 - 0.07 13.5 0.0 0.12 12.8 0.0 1.6 1 1 0 1 1 1 0 YCII-related domain DUF4015 PF13200.6 KFQ97245.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain Herpes_UL6 PF01763.16 KFQ97245.1 - 0.45 9.0 3.3 3.9 5.9 1.2 2.0 2 0 0 2 2 2 0 Herpesvirus UL6 like CPSF73-100_C PF11718.8 KFQ97246.1 - 3.7e-55 186.8 0.2 6.6e-55 186.0 0.2 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KFQ97246.1 - 2.8e-34 117.7 0.0 6.3e-34 116.6 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 KFQ97246.1 - 9.4e-22 76.7 0.2 2e-21 75.7 0.2 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 KFQ97246.1 - 6.4e-19 68.7 0.2 1.1e-18 68.0 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KFQ97246.1 - 1.4e-18 67.1 0.0 3.3e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KFQ97246.1 - 5e-08 32.7 0.3 4e-07 29.8 0.1 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KFQ97246.1 - 2.8e-06 27.3 0.2 6.3e-05 22.9 0.1 3.1 2 1 1 3 3 3 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 KFQ97246.1 - 0.00067 19.0 0.1 0.0017 17.6 0.1 1.7 1 0 0 1 1 1 1 Putative beta-lactamase-like family DUF1611 PF07755.11 KFQ97246.1 - 0.023 14.0 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain Lipase_GDSL_2 PF13472.6 KFQ97247.1 - 2.3e-22 80.2 0.0 3.8e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFQ97247.1 - 3.9e-17 62.9 0.0 4.7e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CP_ATPgrasp_2 PF14403.6 KFQ97247.1 - 0.18 10.7 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 Reprolysin_5 PF13688.6 KFQ97248.1 - 4.4e-37 128.1 0.0 9.1e-37 127.1 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KFQ97248.1 - 1.2e-31 110.1 0.0 2.7e-31 109.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM17_MPD PF16698.5 KFQ97248.1 - 1e-22 80.2 17.0 1e-22 80.2 17.0 4.0 2 1 0 2 2 2 1 Membrane-proximal domain, switch, for ADAM17 Disintegrin PF00200.23 KFQ97248.1 - 4.9e-14 52.9 25.2 4.9e-14 52.9 25.2 3.3 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 KFQ97248.1 - 9.2e-13 48.8 0.1 2e-12 47.7 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 KFQ97248.1 - 5.8e-11 42.7 0.3 1.4e-05 25.1 0.1 3.3 2 1 1 3 3 3 2 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 KFQ97248.1 - 3.5e-08 33.8 0.1 8.8e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_4 PF13583.6 KFQ97248.1 - 2.2e-05 24.2 0.1 3.9e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like 14-3-3 PF00244.20 KFQ97250.1 - 4.1e-107 356.7 5.2 4.7e-107 356.6 5.2 1.0 1 0 0 1 1 1 1 14-3-3 protein FliM PF02154.15 KFQ97250.1 - 0.095 12.6 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Flagellar motor switch protein FliM Peptidase_C98 PF15499.6 KFQ97250.1 - 0.11 11.9 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase XhlA PF10779.9 KFQ97250.1 - 3.1 8.1 4.8 0.8 10.0 1.0 1.9 2 0 0 2 2 2 0 Haemolysin XhlA zf-RRN7 PF11781.8 KFQ97251.1 - 4.5e-10 39.0 4.9 2e-09 37.0 4.9 2.2 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 N6_Mtase PF02384.16 KFQ97251.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 N-6 DNA Methylase CP2 PF04516.15 KFQ97252.1 - 4.1e-81 271.7 2.1 6.1e-81 271.1 2.1 1.2 1 0 0 1 1 1 1 CP2 transcription factor zf-C2H2 PF00096.26 KFQ97253.1 - 2.2e-14 53.0 22.2 7.6e-05 23.0 0.7 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ97253.1 - 1e-11 44.7 9.6 4.4e-07 30.0 1.6 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ97253.1 - 2.1e-07 31.2 20.6 0.0065 17.2 2.2 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFQ97253.1 - 0.00026 21.5 8.1 0.59 10.8 0.1 3.9 2 1 2 4 4 4 2 FOXP coiled-coil domain zf_Hakai PF18408.1 KFQ97253.1 - 0.015 15.0 0.3 0.015 15.0 0.3 2.6 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain zf-C2H2_6 PF13912.6 KFQ97253.1 - 0.035 14.1 0.8 0.035 14.1 0.8 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 KFQ97253.1 - 0.047 14.0 1.4 0.047 14.0 1.4 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF111 PF01969.17 KFQ97253.1 - 0.15 11.1 0.2 0.26 10.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF111 zf-met PF12874.7 KFQ97253.1 - 0.39 11.2 7.2 12 6.5 0.2 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFQ97253.1 - 5.6 7.4 13.5 27 5.2 1.7 3.7 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Ribonuc_red_sm PF00268.21 KFQ97254.1 - 9e-117 389.5 5.4 1.1e-116 389.3 5.4 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain EF-hand_7 PF13499.6 KFQ97256.1 - 3.4e-28 97.9 3.5 2.7e-17 63.0 0.1 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KFQ97256.1 - 5.7e-27 91.2 5.4 3.2e-07 29.4 0.3 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFQ97256.1 - 2.2e-23 80.1 3.7 5.5e-07 29.0 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFQ97256.1 - 1.2e-21 75.2 6.3 3.3e-07 29.5 0.3 4.5 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 KFQ97256.1 - 8.5e-20 70.4 6.3 3.1e-08 33.4 0.1 3.7 3 2 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFQ97256.1 - 4.4e-07 30.2 0.1 0.0071 16.6 0.0 3.3 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFQ97256.1 - 4.8e-06 26.5 0.7 0.18 11.8 0.0 3.4 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 KFQ97256.1 - 0.0025 17.6 0.4 4.1 7.3 0.1 3.0 3 0 0 3 3 3 2 EF hand Dockerin_1 PF00404.18 KFQ97256.1 - 0.0032 17.6 0.0 1.4 9.1 0.0 2.5 2 1 0 2 2 2 2 Dockerin type I domain Orn_Arg_deC_N PF02784.16 KFQ97257.1 - 1e-92 310.0 0.0 1.4e-92 309.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KFQ97257.1 - 2.5e-20 72.5 0.0 3.8e-20 71.9 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain NUC153 PF08159.12 KFQ97260.1 - 1.5e-12 47.0 0.9 3.1e-12 46.1 0.9 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 KFQ97260.1 - 0.091 13.7 0.0 27 5.8 0.0 3.3 4 0 0 4 4 4 0 WD domain, G-beta repeat LLC1 PF14945.6 KFQ97261.1 - 2.1e-06 28.3 6.3 1e-05 26.1 3.1 2.0 1 1 1 2 2 2 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Exonuc_V_gamma PF04257.14 KFQ97261.1 - 0.04 12.1 3.4 0.044 12.0 3.4 1.0 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit Torus PF16131.5 KFQ97261.1 - 0.087 13.5 1.6 0.096 13.4 1.6 1.2 1 0 0 1 1 1 0 Torus domain E2F_CC-MB PF16421.5 KFQ97263.1 - 2.2e-32 111.3 0.6 3.7e-32 110.5 0.6 1.4 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 KFQ97263.1 - 7.7e-24 83.5 0.3 1.6e-23 82.5 0.0 1.6 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain Med4 PF10018.9 KFQ97263.1 - 0.04 13.6 0.1 0.059 13.0 0.1 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 TrmB PF01978.19 KFQ97263.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB FerA PF08165.11 KFQ97263.1 - 0.084 12.8 0.2 0.25 11.3 0.2 1.8 1 0 0 1 1 1 0 FerA (NUC095) domain DUF603 PF04645.12 KFQ97263.1 - 0.12 12.1 0.1 11 5.7 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function, DUF603 GREB1 PF15782.5 KFQ97264.1 - 0 3450.7 20.2 0 3450.4 20.2 1.1 1 0 0 1 1 1 1 Gene regulated by oestrogen in breast cancer PSCyt3 PF07627.11 KFQ97264.1 - 0.31 11.3 2.2 0.97 9.7 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1588) E7 PF00527.18 KFQ97264.1 - 8.3 6.7 11.3 4.4 7.6 0.5 3.5 3 0 0 3 3 3 0 E7 protein, Early protein EPOP PF15223.6 KFQ97267.1 - 3e-123 412.3 6.9 4.2e-123 411.8 6.9 1.1 1 0 0 1 1 1 1 Elongin BC and Polycomb repressive complex 2-associated protein Ski_Sno PF02437.17 KFQ97267.1 - 4.8e-15 55.2 0.1 9.9e-15 54.2 0.1 1.5 1 0 0 1 1 1 1 SKI/SNO/DAC family Nebulin PF00880.18 KFQ97268.1 - 3.5e-32 109.8 1.8 1.4e-12 47.3 0.1 3.3 3 0 0 3 3 3 3 Nebulin repeat SH3_9 PF14604.6 KFQ97268.1 - 2.3e-16 59.4 0.1 3.7e-16 58.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFQ97268.1 - 1.5e-13 50.1 0.0 3.2e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFQ97268.1 - 1.4e-05 24.7 0.0 3.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain RVT_1 PF00078.27 KFQ97269.1 - 0.003 17.1 0.0 0.0074 15.8 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tudor_FRX1 PF18336.1 KFQ97269.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Fragile X mental retardation Tudor domain PSI PF01437.25 KFQ97270.1 - 8.8e-08 32.6 10.9 1.5e-07 31.8 10.9 1.4 1 0 0 1 1 1 1 Plexin repeat MGC-24 PF05283.11 KFQ97270.1 - 0.0013 19.2 7.4 0.0037 17.7 7.4 1.8 1 1 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin PSI_integrin PF17205.3 KFQ97270.1 - 1.9 8.3 9.1 3.2 7.6 9.1 1.4 1 0 0 1 1 1 0 Integrin plexin domain PetM PF08041.11 KFQ97271.1 - 0.036 13.7 2.0 0.036 13.7 2.0 1.6 2 0 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 Amnionless PF14828.6 KFQ97271.1 - 0.041 12.7 0.0 0.043 12.6 0.0 1.1 1 0 0 1 1 1 0 Amnionless Viral_Beta_CD PF04530.12 KFQ97271.1 - 0.077 13.3 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Viral Beta C/D like family MAM PF00629.23 KFQ97272.1 - 9.9e-24 84.1 2.4 1.1e-23 83.9 2.4 1.0 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu MAM PF00629.23 KFQ97273.1 - 3.9e-20 72.4 0.8 4.3e-20 72.2 0.8 1.0 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu HIGH_NTase1 PF05636.11 KFQ97273.1 - 0.077 12.2 0.0 0.077 12.2 0.0 1.1 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase zf-C4H2 PF10146.9 KFQ97275.1 - 0.012 15.9 17.4 0.074 13.3 17.1 2.3 1 1 0 1 1 1 0 Zinc finger-containing protein CENP-F_leu_zip PF10473.9 KFQ97275.1 - 0.17 11.9 17.6 0.24 11.4 8.1 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cdh1_DBD_1 PF18196.1 KFQ97275.1 - 0.56 10.5 5.3 0.96 9.8 3.0 2.5 2 1 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 BRE1 PF08647.11 KFQ97275.1 - 1.5 9.0 13.3 3.4 7.8 8.2 2.6 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase FAM76 PF16046.5 KFQ97275.1 - 5.5 6.2 14.6 0.56 9.5 9.2 1.9 1 1 1 2 2 2 0 FAM76 protein Ank_2 PF12796.7 KFQ97276.1 - 2.4e-49 165.9 14.8 8e-17 61.6 0.4 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFQ97276.1 - 1.1e-32 108.4 1.9 5.1e-05 23.4 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KFQ97276.1 - 5.6e-31 106.2 5.4 5.2e-08 33.0 0.1 5.7 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFQ97276.1 - 2.5e-29 101.3 10.2 6.4e-09 36.2 0.1 5.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KFQ97276.1 - 3.9e-25 87.1 8.6 2.2e-05 24.7 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat Death PF00531.22 KFQ97276.1 - 0.05 13.8 3.4 0.051 13.7 1.6 2.0 2 0 0 2 2 2 0 Death domain Herpes_U15 PF05613.11 KFQ97276.1 - 0.094 13.4 0.0 3.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Human herpesvirus U15 protein IMS PF00817.20 KFQ97277.1 - 9.4e-44 149.0 0.0 4e-43 147.0 0.0 2.1 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 KFQ97277.1 - 5.1e-17 62.7 0.9 1.4e-16 61.3 0.3 2.1 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KFQ97277.1 - 3.5e-09 36.5 0.1 8.2e-09 35.3 0.1 1.7 1 0 0 1 1 1 1 IMS family HHH motif zf-C2H2_12 PF18658.1 KFQ97277.1 - 5.6e-06 25.8 1.4 0.031 13.8 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger C2H2-type Cdd1 PF11731.8 KFQ97277.1 - 0.06 13.6 0.0 0.22 11.8 0.0 1.9 1 0 0 1 1 1 0 Pathogenicity locus zf-Di19 PF05605.12 KFQ97277.1 - 0.076 13.3 4.6 5.1 7.5 0.4 2.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KFQ97277.1 - 1.5 9.5 5.1 12 6.6 0.0 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type START PF01852.19 KFQ97278.1 - 1.2e-30 106.4 1.2 1.9e-30 105.8 0.3 1.8 2 0 0 2 2 2 1 START domain PH PF00169.29 KFQ97278.1 - 1.7e-12 47.8 0.8 5.1e-12 46.2 0.8 1.9 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFQ97278.1 - 2.7e-07 30.8 0.0 9.3e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFQ97278.1 - 0.00056 20.3 1.9 0.053 13.9 0.6 3.1 2 1 0 2 2 2 1 Pleckstrin homology domain Acyl_CoA_thio PF02551.15 KFQ97278.1 - 0.018 14.9 0.0 0.043 13.6 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA thioesterase CREPT PF16566.5 KFQ97278.1 - 0.12 12.5 0.5 0.25 11.5 0.1 1.7 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Med18 PF09637.10 KFQ97279.1 - 1.5e-28 100.3 0.0 1.9e-28 100.0 0.0 1.0 1 0 0 1 1 1 1 Med18 protein Ank_4 PF13637.6 KFQ97280.1 - 4.6e-19 68.5 0.9 1.2e-07 32.1 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFQ97280.1 - 2.8e-14 53.0 1.5 4.4e-06 26.9 0.1 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFQ97280.1 - 1.1e-12 48.3 0.1 9.6e-11 42.1 0.1 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFQ97280.1 - 1.4e-12 47.4 0.1 1.1e-06 28.8 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KFQ97280.1 - 7.1e-12 44.4 0.0 0.00036 20.7 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Peptidase_C1 PF00112.23 KFQ97283.1 - 4.8e-14 53.0 1.5 4.8e-14 53.0 1.5 1.8 1 1 1 2 2 2 1 Papain family cysteine protease G-alpha PF00503.20 KFQ97284.1 - 5.4e-103 344.9 1.4 6.1e-103 344.7 1.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFQ97284.1 - 1.9e-14 53.5 1.5 1.4e-13 50.7 0.5 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 KFQ97284.1 - 0.001 19.3 1.6 0.028 14.6 0.2 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KFQ97284.1 - 0.021 14.4 0.0 0.33 10.5 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Peptidase_M17 PF00883.21 KFQ97285.1 - 4.7e-101 338.1 0.1 6.1e-101 337.8 0.1 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 KFQ97285.1 - 4.6e-17 62.4 0.3 1.7e-16 60.6 0.1 2.0 2 0 0 2 2 2 1 M17 aminopeptidase N-terminal domain 2 SNARE PF05739.19 KFQ97286.1 - 2.2e-19 69.2 2.3 2.2e-19 69.2 2.3 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KFQ97286.1 - 0.00022 21.0 13.1 0.00022 21.0 13.1 2.1 2 1 0 2 2 2 1 Syntaxin TRP PF06011.12 KFQ97286.1 - 0.017 13.9 0.0 0.021 13.6 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Syntaxin_2 PF14523.6 KFQ97286.1 - 0.018 15.4 12.1 0.12 12.7 6.1 2.6 2 1 0 2 2 2 0 Syntaxin-like protein DUF2116 PF09889.9 KFQ97286.1 - 0.026 14.5 1.3 0.066 13.2 1.3 1.7 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF3140 PF11338.8 KFQ97286.1 - 0.038 14.4 0.2 0.092 13.2 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3140) ETRAMP PF09716.10 KFQ97286.1 - 0.046 13.8 0.0 0.055 13.5 0.0 1.5 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF5345 PF17280.2 KFQ97286.1 - 0.087 12.8 0.1 0.087 12.8 0.1 1.9 2 0 0 2 2 1 0 Family of unknown function (DUF5345) Orf78 PF06024.12 KFQ97286.1 - 0.089 13.1 0.5 0.22 11.8 0.5 1.6 1 0 0 1 1 1 0 Orf78 (ac78) DUF4191 PF13829.6 KFQ97286.1 - 0.14 11.5 1.7 0.18 11.1 0.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DASH_Dam1 PF08653.10 KFQ97286.1 - 0.18 11.6 2.4 30 4.5 0.0 3.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 Prominin PF05478.11 KFQ97286.1 - 0.28 9.1 10.8 0.12 10.3 2.4 2.1 2 0 0 2 2 2 0 Prominin T2SSF PF00482.23 KFQ97286.1 - 0.36 10.8 8.1 5.7 6.9 0.2 3.4 4 0 0 4 4 4 0 Type II secretion system (T2SS), protein F EVI2A PF05399.11 KFQ97286.1 - 0.46 10.0 3.9 0.6 9.7 0.4 2.4 2 1 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) SKA1 PF07160.12 KFQ97286.1 - 0.62 9.9 11.8 0.66 9.8 1.8 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 MCPsignal PF00015.21 KFQ97286.1 - 1.3 8.8 5.0 9 6.1 0.2 2.5 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TMPIT PF07851.13 KFQ97286.1 - 1.5 8.0 10.5 1.2 8.3 2.6 2.4 2 1 0 2 2 2 0 TMPIT-like protein Use1 PF09753.9 KFQ97286.1 - 1.9 8.2 11.9 23 4.6 11.9 2.3 1 1 0 1 1 1 0 Membrane fusion protein Use1 Syntaxin-6_N PF09177.11 KFQ97286.1 - 3.5 8.3 9.5 2.5 8.7 3.7 3.0 2 2 0 2 2 2 0 Syntaxin 6, N-terminal Synaptobrevin PF00957.21 KFQ97286.1 - 4.3 7.2 15.1 0.26 11.1 6.0 3.3 3 2 0 3 3 3 0 Synaptobrevin DUF2203 PF09969.9 KFQ97286.1 - 6.9 7.4 7.3 14 6.5 0.8 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) APCDDC PF14921.6 KFQ97287.1 - 1.8e-119 397.4 0.0 1.1e-87 293.4 0.0 2.2 2 0 0 2 2 2 2 Adenomatosis polyposis coli down-regulated 1 Motile_Sperm PF00635.26 KFQ97288.1 - 1.8e-29 101.8 0.1 3.4e-29 100.9 0.1 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ZapB PF06005.12 KFQ97288.1 - 0.0054 17.1 0.4 0.009 16.4 0.4 1.3 1 0 0 1 1 1 1 Cell division protein ZapB Com_YlbF PF06133.11 KFQ97288.1 - 0.035 14.7 0.6 0.062 13.9 0.6 1.3 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA LcrG PF07216.12 KFQ97288.1 - 0.046 13.7 0.3 0.08 12.9 0.3 1.3 1 0 0 1 1 1 0 LcrG protein IF2_N PF04760.15 KFQ97288.1 - 0.064 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region CHD5 PF04420.14 KFQ97288.1 - 0.15 11.9 1.0 0.45 10.4 0.9 1.7 2 0 0 2 2 2 0 CHD5-like protein Ras PF00071.22 KFQ97289.1 - 6.8e-56 188.3 0.0 7.8e-56 188.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ97289.1 - 2.5e-36 124.5 0.0 3.9e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ97289.1 - 1.9e-14 53.5 0.0 2e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFQ97289.1 - 3.6e-05 23.8 0.0 7.1e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFQ97289.1 - 7.4e-05 22.2 0.0 9.7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFQ97289.1 - 0.00012 21.7 0.0 0.00052 19.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFQ97289.1 - 0.00037 20.4 0.6 0.13 12.2 0.0 2.4 1 1 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 KFQ97289.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KFQ97289.1 - 0.013 15.9 0.0 0.026 14.9 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KFQ97289.1 - 0.049 13.4 0.0 0.1 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain DIT1_PvcA PF05141.12 KFQ97289.1 - 0.076 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein CNTF PF01110.17 KFQ97289.1 - 0.076 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Ciliary neurotrophic factor AAA_5 PF07728.14 KFQ97289.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) HEAT PF02985.22 KFQ97290.1 - 1.9e-24 83.6 13.0 0.0086 16.3 0.0 9.4 8 0 0 8 8 8 7 HEAT repeat HEAT_2 PF13646.6 KFQ97290.1 - 1.4e-09 38.2 2.0 0.19 12.1 0.0 7.0 4 3 3 8 8 8 4 HEAT repeats WRNPLPNID PF15017.6 KFQ97290.1 - 4.5e-07 30.6 0.1 4.5e-07 30.6 0.1 3.0 3 1 0 3 3 3 1 Putative WW-binding domain and destruction box Cnd1 PF12717.7 KFQ97290.1 - 0.0016 18.5 7.6 7.3 6.6 0.1 5.8 4 2 3 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KFQ97290.1 - 0.0017 18.9 1.9 5.3 7.7 0.0 5.3 4 3 3 7 7 7 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KFQ97290.1 - 0.037 14.5 0.3 2.6 8.7 0.2 3.7 3 0 0 3 3 3 0 HEAT-like repeat MID_MedPIWI PF18296.1 KFQ97290.1 - 6.5 6.5 11.2 0.26 11.0 0.6 2.3 2 0 0 2 2 2 0 MID domain of medPIWI LLC1 PF14945.6 KFQ97291.1 - 7.4e-44 149.1 2.3 8.1e-44 149.0 2.3 1.0 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein TMEM154 PF15102.6 KFQ97292.1 - 0.03 14.2 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family ECSCR PF15820.5 KFQ97292.1 - 0.11 12.4 0.3 0.19 11.6 0.3 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator PEPCK_GTP PF00821.18 KFQ97293.1 - 2.2e-168 559.7 0.3 2.7e-168 559.4 0.3 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 KFQ97293.1 - 3.6e-98 327.5 0.0 4.8e-98 327.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain TPK_catalytic PF04263.16 KFQ97293.1 - 0.1 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain zf-H2C2_2 PF13465.6 KFQ97294.1 - 5e-35 118.4 59.0 1.8e-08 34.4 0.4 8.2 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ97294.1 - 3.6e-19 68.1 65.6 3.6e-05 24.0 1.0 9.0 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ97294.1 - 2.3e-18 65.3 63.4 0.0031 18.2 0.4 9.1 9 0 0 9 9 9 6 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFQ97294.1 - 5.2e-14 51.7 66.0 7.4e-06 25.6 1.8 9.5 9 1 0 9 9 9 5 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KFQ97294.1 - 0.0015 18.8 42.1 0.088 13.1 1.8 5.3 2 2 1 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding AKAP95 PF04988.12 KFQ97294.1 - 0.0056 16.9 0.7 0.0056 16.9 0.7 3.9 3 2 0 3 3 3 1 A-kinase anchoring protein 95 (AKAP95) zinc_ribbon_15 PF17032.5 KFQ97294.1 - 0.006 17.3 21.6 5.7 7.8 0.3 4.1 4 0 0 4 4 4 3 zinc-ribbon family DiS_P_DiS PF06750.13 KFQ97294.1 - 0.072 13.2 0.7 0.072 13.2 0.7 2.9 4 1 0 4 4 4 0 Bacterial Peptidase A24 N-terminal domain zf-C2H2_11 PF16622.5 KFQ97294.1 - 0.09 12.6 0.5 0.09 12.6 0.5 6.9 8 0 0 8 8 8 0 zinc-finger C2H2-type zf-C2H2_10 PF16588.5 KFQ97294.1 - 0.25 11.1 0.3 0.25 11.1 0.3 4.3 5 0 0 5 5 5 0 C2H2 zinc-finger Zn_Tnp_IS1595 PF12760.7 KFQ97294.1 - 2.5 8.1 28.8 5.5 7.1 1.2 4.8 4 1 0 4 4 4 0 Transposase zinc-ribbon domain PHD PF00628.29 KFQ97294.1 - 7.2 6.6 27.4 0.13 12.2 2.4 5.3 4 2 0 5 5 5 0 PHD-finger WD40 PF00400.32 KFQ97296.1 - 1.1e-10 41.9 17.4 0.02 15.8 0.2 5.8 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ97296.1 - 0.00071 19.8 0.0 0.97 9.8 0.2 3.6 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFQ97296.1 - 0.0097 14.6 0.4 0.92 8.1 0.1 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 TP6A_N PF04406.14 KFQ97297.1 - 1e-23 83.0 0.1 1.9e-23 82.2 0.1 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF760 PF05542.11 KFQ97297.1 - 0.046 14.1 0.2 2.4 8.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF760) TGFb_propeptide PF00688.18 KFQ97298.1 - 5.2e-68 229.4 0.0 8.4e-68 228.8 0.0 1.3 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 KFQ97298.1 - 2e-37 128.3 0.9 6e-37 126.8 0.7 1.9 2 0 0 2 2 2 1 Transforming growth factor beta like domain DUF3504 PF12012.8 KFQ97298.1 - 0.088 12.7 0.1 3.4 7.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3504) TF_AP-2 PF03299.14 KFQ97299.1 - 3.9e-88 294.6 0.0 4.6e-88 294.3 0.0 1.1 1 0 0 1 1 1 1 Transcription factor AP-2 4PPT_N PF17837.1 KFQ97299.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain Rtf2 PF04641.12 KFQ97300.1 - 2.7e-85 285.9 10.7 3.2e-85 285.7 10.7 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 KFQ97300.1 - 0.024 14.8 0.1 0.061 13.5 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein MAS20 PF02064.15 KFQ97300.1 - 0.59 10.2 3.0 0.61 10.2 1.9 1.5 1 1 0 1 1 1 0 MAS20 protein import receptor Branch PF02485.21 KFQ97301.1 - 5.9e-53 179.9 0.3 5.9e-53 179.9 0.3 1.5 2 0 0 2 2 2 1 Core-2/I-Branching enzyme WD40 PF00400.32 KFQ97302.1 - 3.6e-33 113.1 1.8 2.1e-06 28.3 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat CSTF1_dimer PF16699.5 KFQ97302.1 - 8.7e-23 79.8 0.3 1.5e-22 79.1 0.3 1.4 1 0 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain ANAPC4_WD40 PF12894.7 KFQ97302.1 - 2.9e-12 46.7 0.0 0.017 15.4 0.0 4.7 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KFQ97302.1 - 6.5e-06 24.7 0.1 0.00012 20.6 0.0 2.2 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KFQ97302.1 - 0.0017 17.4 1.0 0.6 9.0 0.2 2.9 1 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Pkinase PF00069.25 KFQ97303.1 - 3.2e-69 233.2 0.0 4.5e-69 232.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ97303.1 - 2.1e-41 142.0 0.0 3e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ97303.1 - 1.1e-05 24.9 0.0 8.1e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.9 KFQ97303.1 - 0.015 14.8 0.5 0.039 13.5 0.0 1.9 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL APH PF01636.23 KFQ97303.1 - 0.028 14.4 0.0 0.056 13.4 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KFQ97303.1 - 0.03 14.0 0.1 1.5 8.4 0.0 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 KFQ97303.1 - 0.066 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3408 PF11888.8 KFQ97303.1 - 1.2 9.3 5.9 2.4 8.3 5.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Ndc1_Nup PF09531.10 KFQ97303.1 - 1.4 7.5 4.1 1.7 7.3 4.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 KFQ97303.1 - 1.4 7.6 4.4 1.9 7.2 4.4 1.1 1 0 0 1 1 1 0 Presenilin DUF1279 PF06916.13 KFQ97304.1 - 9.8e-29 99.8 1.1 1.2e-28 99.5 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) YiaAB PF05360.14 KFQ97304.1 - 2.6 8.4 6.1 0.59 10.4 1.6 2.0 2 1 0 2 2 2 0 yiaA/B two helix domain 7tm_1 PF00001.21 KFQ97305.1 - 1.3e-36 126.3 38.2 4e-35 121.4 38.2 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFQ97305.1 - 3.4e-08 33.6 29.1 1.3e-07 31.6 24.8 2.7 1 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KFQ97305.1 - 5e-06 26.1 38.1 1.2e-05 24.9 38.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFQ97305.1 - 0.00045 19.9 28.1 0.00045 19.9 28.1 2.8 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx ANAPC9 PF12856.7 KFQ97306.1 - 0.13 12.5 2.0 0.44 10.7 2.0 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 9 C1q PF00386.21 KFQ97307.1 - 3.7e-19 69.2 0.4 4.1e-19 69.1 0.4 1.0 1 0 0 1 1 1 1 C1q domain PH_2 PF08458.10 KFQ97307.1 - 0.037 14.4 0.0 7.9 6.9 0.0 2.1 1 1 1 2 2 2 0 Plant pleckstrin homology-like region IRS PF02174.17 KFQ97308.1 - 2.6e-29 101.1 0.0 3.8e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 PTB domain (IRS-1 type) Prefoldin_2 PF01920.20 KFQ97309.1 - 3.1e-25 88.2 8.4 3.9e-25 87.9 8.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit NPV_P10 PF05531.12 KFQ97309.1 - 8.5e-06 26.1 1.7 0.0061 17.0 0.3 2.2 2 0 0 2 2 2 2 Nucleopolyhedrovirus P10 protein DUF5082 PF16888.5 KFQ97309.1 - 0.00022 21.5 10.8 0.00078 19.7 10.8 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF5082) Helo_like_N PF17111.5 KFQ97309.1 - 0.00041 19.8 1.8 0.26 10.6 0.1 2.1 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins DUF5320 PF17253.2 KFQ97309.1 - 0.0013 19.8 3.7 0.0061 17.6 0.3 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5320) Prefoldin PF02996.17 KFQ97309.1 - 0.0023 17.8 8.6 0.18 11.7 8.6 2.2 1 1 0 1 1 1 1 Prefoldin subunit KxDL PF10241.9 KFQ97309.1 - 0.0031 17.8 6.5 0.017 15.4 0.8 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein FlxA PF14282.6 KFQ97309.1 - 0.0093 15.9 7.8 0.46 10.5 0.3 2.3 2 0 0 2 2 2 2 FlxA-like protein DUF4140 PF13600.6 KFQ97309.1 - 0.0099 16.3 4.6 0.84 10.1 0.1 2.1 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) Med30 PF11315.8 KFQ97309.1 - 0.01 16.0 3.9 0.013 15.7 3.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 30 Spectrin PF00435.21 KFQ97309.1 - 0.012 16.1 5.0 0.28 11.7 0.5 2.2 2 0 0 2 2 2 0 Spectrin repeat DUF4618 PF15397.6 KFQ97309.1 - 0.012 15.1 6.1 0.14 11.5 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DivIC PF04977.15 KFQ97309.1 - 0.012 15.4 5.0 0.52 10.1 0.3 2.4 2 0 0 2 2 2 0 Septum formation initiator UPF0054 PF02130.17 KFQ97309.1 - 0.012 15.4 3.0 0.031 14.1 3.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein family UPF0054 Fib_alpha PF08702.10 KFQ97309.1 - 0.015 15.5 7.4 0.87 9.8 1.6 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family YabA PF06156.13 KFQ97309.1 - 0.019 15.6 4.8 0.14 12.8 0.5 2.4 2 1 0 2 2 2 0 Initiation control protein YabA FliD_C PF07195.12 KFQ97309.1 - 0.019 14.4 4.2 0.035 13.5 0.1 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Cep57_CLD_2 PF14197.6 KFQ97309.1 - 0.022 14.8 8.6 0.92 9.6 1.0 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Spc24 PF08286.11 KFQ97309.1 - 0.024 14.9 6.7 0.44 10.8 1.6 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TPR_MLP1_2 PF07926.12 KFQ97309.1 - 0.026 14.6 12.4 0.2 11.8 4.5 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Rx_N PF18052.1 KFQ97309.1 - 0.029 14.6 5.1 0.11 12.7 0.9 2.2 2 0 0 2 2 2 0 Rx N-terminal domain BLI1 PF17324.2 KFQ97309.1 - 0.031 14.9 6.4 0.32 11.7 1.1 2.2 2 0 0 2 2 2 0 BLOC-1 interactor 1 RraB PF06877.11 KFQ97309.1 - 0.032 15.0 3.3 0.24 12.2 0.3 2.3 1 1 1 2 2 2 0 Regulator of ribonuclease activity B Seryl_tRNA_N PF02403.22 KFQ97309.1 - 0.038 14.2 8.0 1.2 9.4 0.5 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ABC_tran_CTD PF16326.5 KFQ97309.1 - 0.038 14.2 10.8 0.35 11.2 3.6 2.5 2 1 0 2 2 2 0 ABC transporter C-terminal domain DUF1664 PF07889.12 KFQ97309.1 - 0.041 13.9 5.9 0.096 12.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KFQ97309.1 - 0.047 14.1 9.0 1.6 9.2 1.2 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4854 PF16146.5 KFQ97309.1 - 0.049 14.0 2.8 0.057 13.7 2.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4854) Fzo_mitofusin PF04799.13 KFQ97309.1 - 0.066 12.8 4.2 0.69 9.4 0.4 2.1 2 0 0 2 2 2 0 fzo-like conserved region Atg14 PF10186.9 KFQ97309.1 - 0.066 12.3 2.4 0.13 11.3 2.4 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2721 PF11026.8 KFQ97309.1 - 0.066 13.1 0.8 5.2 7.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) CdvA PF18822.1 KFQ97309.1 - 0.075 12.9 9.2 0.093 12.6 2.5 2.2 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Mod_r PF07200.13 KFQ97309.1 - 0.1 12.7 9.5 0.5 10.5 9.5 1.9 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein APG6_N PF17675.1 KFQ97309.1 - 0.13 12.8 12.6 0.79 10.3 4.2 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region PP2C_2 PF13672.6 KFQ97309.1 - 0.13 11.8 0.1 0.15 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein phosphatase 2C GvpL_GvpF PF06386.11 KFQ97309.1 - 0.16 11.8 2.7 0.45 10.4 0.2 1.9 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF UPF0242 PF06785.11 KFQ97309.1 - 0.24 11.5 12.0 0.48 10.5 12.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DASH_Spc34 PF08657.10 KFQ97309.1 - 0.26 11.1 7.4 0.81 9.4 6.3 1.9 1 1 1 2 2 2 0 DASH complex subunit Spc34 V_ATPase_I PF01496.19 KFQ97309.1 - 0.26 9.2 4.1 0.31 8.9 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CCDC-167 PF15188.6 KFQ97309.1 - 0.32 11.4 8.8 0.76 10.2 3.5 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Mt_ATP-synt_D PF05873.12 KFQ97309.1 - 0.34 10.8 5.2 0.79 9.6 0.2 2.1 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) HalX PF08663.10 KFQ97309.1 - 0.34 11.3 5.0 8.1 6.9 1.6 2.4 2 0 0 2 2 2 0 HalX domain Med9 PF07544.13 KFQ97309.1 - 0.36 10.9 13.9 1.3 9.2 3.8 3.3 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 TBCA PF02970.16 KFQ97309.1 - 0.39 11.1 9.4 1.3 9.4 9.0 2.1 1 1 0 1 1 1 0 Tubulin binding cofactor A TMF_DNA_bd PF12329.8 KFQ97309.1 - 0.4 10.7 13.0 2.1 8.4 1.3 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FAM76 PF16046.5 KFQ97309.1 - 0.44 9.9 7.5 0.72 9.1 7.5 1.4 1 1 0 1 1 1 0 FAM76 protein Csm1_N PF18504.1 KFQ97309.1 - 0.44 10.9 9.6 3.4 8.1 1.5 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain eIF3_N PF09440.10 KFQ97309.1 - 0.49 10.8 6.2 1 9.8 0.3 2.1 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain FmiP_Thoc5 PF09766.9 KFQ97309.1 - 0.51 9.6 7.7 1.9 7.7 1.4 2.1 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 DASH_Dam1 PF08653.10 KFQ97309.1 - 0.53 10.1 2.3 6.7 6.6 0.2 2.6 2 1 1 3 3 3 0 DASH complex subunit Dam1 DUF4988 PF16378.5 KFQ97309.1 - 0.57 9.8 4.7 2.5 7.7 0.2 2.4 2 1 1 3 3 2 0 Domain of unknown function UPF0449 PF15136.6 KFQ97309.1 - 0.58 10.7 8.4 2.7 8.5 1.6 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF2203 PF09969.9 KFQ97309.1 - 0.69 10.7 5.8 2.6 8.8 5.3 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) BORCS7 PF16088.5 KFQ97309.1 - 0.7 10.2 7.5 5.8 7.2 0.3 2.2 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 Med4 PF10018.9 KFQ97309.1 - 0.73 9.5 8.3 1.2 8.7 0.9 2.2 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Plk4_PB2 PF18409.1 KFQ97309.1 - 0.91 10.2 6.0 11 6.7 6.0 2.1 1 1 0 1 1 1 0 Polo-like Kinase 4 Polo Box 2 DUF4407 PF14362.6 KFQ97309.1 - 0.97 8.7 7.1 2.8 7.2 7.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) KfrA_N PF11740.8 KFQ97309.1 - 1.3 9.8 8.3 1.5 9.6 6.8 1.9 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Fmp27_WPPW PF10359.9 KFQ97309.1 - 1.5 7.6 9.0 0.49 9.2 1.8 2.0 1 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain CHD5 PF04420.14 KFQ97309.1 - 1.6 8.6 4.0 2.3 8.0 0.7 2.0 2 0 0 2 2 2 0 CHD5-like protein AAA_23 PF13476.6 KFQ97309.1 - 1.6 9.2 11.5 2.5 8.6 11.5 1.3 1 1 0 1 1 1 0 AAA domain SlyX PF04102.12 KFQ97309.1 - 1.9 9.2 8.4 2.6 8.7 1.2 2.5 2 1 0 2 2 2 0 SlyX GrpE PF01025.19 KFQ97309.1 - 2 8.0 10.8 2.1 8.0 2.2 2.1 2 0 0 2 2 2 0 GrpE bZIP_1 PF00170.21 KFQ97309.1 - 2.3 8.4 10.3 4.1 7.6 3.5 2.3 2 0 0 2 2 2 0 bZIP transcription factor ERM PF00769.19 KFQ97309.1 - 2.4 7.9 13.6 0.52 10.1 4.0 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family YtxH PF12732.7 KFQ97309.1 - 2.7 8.6 5.0 6.5 7.4 0.1 2.3 2 0 0 2 2 2 0 YtxH-like protein DUF2205 PF10224.9 KFQ97309.1 - 3.7 7.6 9.8 0.36 10.9 2.9 2.2 1 1 1 2 2 2 0 Short coiled-coil protein FliD_N PF02465.18 KFQ97309.1 - 3.9 8.2 6.6 19 6.1 0.7 2.2 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Carbpep_Y_N PF05388.11 KFQ97309.1 - 5.5 7.5 7.6 5.1 7.7 0.4 2.8 2 1 1 3 3 3 0 Carboxypeptidase Y pro-peptide PCRF PF03462.18 KFQ97309.1 - 6.9 6.5 11.0 78 3.0 11.0 2.0 1 1 0 1 1 1 0 PCRF domain Med7 PF05983.11 KFQ97309.1 - 7.2 6.6 8.8 8.9 6.3 2.5 2.3 2 0 0 2 2 2 0 MED7 protein DUF812 PF05667.11 KFQ97309.1 - 8.9 5.1 16.3 5 5.9 4.7 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF812) p450 PF00067.22 KFQ97310.1 - 2.1e-83 280.6 0.2 2.4e-83 280.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2 PF00096.26 KFQ97313.1 - 4.5e-20 70.9 50.3 0.00017 21.9 1.0 9.0 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ97313.1 - 4e-18 64.5 53.6 0.001 19.7 0.9 8.9 8 0 0 8 8 8 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFQ97313.1 - 1.3e-09 38.1 63.7 1.1e-07 32.0 0.4 11.8 13 0 0 13 13 12 4 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFQ97313.1 - 4.6e-05 23.1 3.1 4.6e-05 23.1 3.1 8.7 9 1 0 9 9 9 3 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 KFQ97313.1 - 6e-05 23.7 17.9 0.00015 22.4 1.2 5.7 5 1 1 6 6 6 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 KFQ97313.1 - 0.0007 19.9 2.2 0.0007 19.9 2.2 7.1 5 2 1 7 7 7 1 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KFQ97313.1 - 0.014 15.4 1.0 0.014 15.4 1.0 7.9 7 2 0 7 7 7 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFQ97313.1 - 0.18 11.8 15.0 0.65 10.0 0.8 5.7 5 0 0 5 5 5 0 zinc-finger of a C2HC-type CpXC PF14353.6 KFQ97313.1 - 0.23 11.5 14.9 3.8 7.6 0.1 5.8 4 1 0 4 4 4 0 CpXC protein zf-C2H2_jaz PF12171.8 KFQ97313.1 - 0.81 10.1 28.1 0.8 10.1 0.9 6.3 6 0 0 6 6 5 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 KFQ97313.1 - 0.83 9.3 14.9 4.8 6.9 0.1 5.4 5 0 0 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain Actin_micro PF17003.5 KFQ97313.1 - 0.94 8.6 15.2 4 6.5 0.9 3.8 2 1 0 3 3 3 0 Putative actin-like family GAGA PF09237.11 KFQ97313.1 - 1.3 8.9 5.0 1.7 8.5 0.1 3.0 3 0 0 3 3 2 0 GAGA factor AKAP95 PF04988.12 KFQ97313.1 - 1.7 8.9 15.8 2 8.6 1.4 4.0 4 0 0 4 4 4 0 A-kinase anchoring protein 95 (AKAP95) C1_1 PF00130.22 KFQ97313.1 - 2.2 8.3 19.0 1.4 8.8 0.8 4.9 4 1 1 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2256 PF10013.9 KFQ97313.1 - 2.3 8.4 10.2 43 4.3 0.0 5.3 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_4 PF13894.6 KFQ97315.1 - 8.9e-10 38.6 28.7 0.049 14.5 0.1 6.1 6 0 0 6 6 5 4 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFQ97315.1 - 1.9e-09 37.7 26.9 0.005 17.1 0.3 4.7 3 1 1 4 4 4 4 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 KFQ97315.1 - 1.5e-05 25.7 16.5 0.18 12.5 0.8 5.1 3 1 1 4 4 4 3 Zinc finger C2H2-type, 3 repeats zf-C2H2 PF00096.26 KFQ97315.1 - 0.00031 21.0 34.3 0.37 11.3 0.8 6.1 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-met PF12874.7 KFQ97315.1 - 0.0022 18.3 12.1 0.11 13.0 0.4 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFQ97315.1 - 0.02 15.2 15.5 0.035 14.4 0.2 3.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFQ97315.1 - 0.057 13.4 24.7 0.45 10.6 0.2 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger Zn_Tnp_IS1 PF03811.13 KFQ97315.1 - 0.51 10.1 3.5 8.9 6.1 0.9 2.9 2 0 0 2 2 2 0 InsA N-terminal domain PhnA_Zn_Ribbon PF08274.12 KFQ97315.1 - 1.2 9.2 3.7 3.6 7.6 0.0 2.9 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-CpG_bind_C PF12269.8 KFQ97315.1 - 1.9 8.2 13.8 0.11 12.3 2.1 3.2 3 0 0 3 3 3 0 CpG binding protein zinc finger C terminal domain zf-H2C2_2 PF13465.6 KFQ97315.1 - 3.3 8.3 18.8 7.1 7.2 0.3 5.8 5 0 0 5 5 5 0 Zinc-finger double domain zf-C2H2_12 PF18658.1 KFQ97315.1 - 5.3 6.7 11.0 5.4 6.7 0.0 3.9 4 0 0 4 4 4 0 Zinc-finger C2H2-type PhoLip_ATPase_C PF16212.5 KFQ97316.1 - 1.8e-51 175.3 24.4 1.8e-51 175.3 24.4 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFQ97316.1 - 3.9e-17 61.7 3.3 1e-16 60.3 3.3 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFQ97316.1 - 2.9e-14 53.8 2.8 3.1e-11 44.0 2.8 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFQ97316.1 - 1.2e-10 41.2 0.0 1.2e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KFQ97316.1 - 2.1e-08 34.1 0.0 2.9e-07 30.5 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFQ97316.1 - 0.0059 16.4 0.0 0.03 14.1 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RHD_dimer PF16179.5 KFQ97317.1 - 4.3e-25 87.7 0.4 1.1e-24 86.4 0.4 1.7 1 0 0 1 1 1 1 Rel homology dimerisation domain RHD_DNA_bind PF00554.22 KFQ97317.1 - 2e-22 80.0 0.5 5.8e-22 78.4 0.5 1.8 1 1 0 1 1 1 1 Rel homology DNA-binding domain TIG PF01833.24 KFQ97317.1 - 2.8e-06 27.3 0.2 1.6e-05 24.9 0.0 2.5 2 0 0 2 2 2 1 IPT/TIG domain Ion_trans PF00520.31 KFQ97318.1 - 2.6e-37 128.4 9.3 3.8e-37 127.8 9.3 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFQ97318.1 - 1.3e-26 92.8 0.0 2.8e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFQ97318.1 - 4.4e-14 52.2 3.0 4.4e-14 52.2 3.0 2.0 2 0 0 2 2 2 1 Ion channel ThiF PF00899.21 KFQ97319.1 - 1e-64 218.3 0.0 1.4e-64 217.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KFQ97319.1 - 8.8e-11 42.3 0.0 1.8e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain FAD_binding_3 PF01494.19 KFQ97319.1 - 0.17 11.1 0.1 0.22 10.7 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Glycos_transf_2 PF00535.26 KFQ97320.1 - 1.8e-33 115.8 0.0 2.1e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KFQ97320.1 - 1.3e-09 38.3 0.0 3.1e-09 37.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KFQ97320.1 - 6e-05 22.6 0.0 0.00011 21.7 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 KFQ97320.1 - 0.00039 20.0 0.0 0.00059 19.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KFQ97320.1 - 0.13 12.8 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Homeodomain PF00046.29 KFQ97321.1 - 1.1e-07 31.5 0.2 5.1e-07 29.4 0.5 2.0 2 0 0 2 2 2 1 Homeodomain zf-C2H2_4 PF13894.6 KFQ97321.1 - 0.00064 20.3 53.3 0.011 16.5 0.3 9.4 9 0 0 9 9 9 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KFQ97321.1 - 0.055 14.2 11.5 4.1 8.1 0.5 4.9 4 0 0 4 4 4 0 Zinc finger C2H2-type, 3 repeats Homeobox_KN PF05920.11 KFQ97321.1 - 0.079 12.9 0.3 0.28 11.1 0.3 1.9 1 0 0 1 1 1 0 Homeobox KN domain zf-Di19 PF05605.12 KFQ97321.1 - 0.088 13.1 0.2 0.088 13.1 0.2 7.5 7 2 1 8 8 8 0 Drought induced 19 protein (Di19), zinc-binding Thioredoxin_3 PF13192.6 KFQ97321.1 - 0.21 11.7 3.8 8.4 6.5 0.0 4.7 5 0 0 5 5 5 0 Thioredoxin domain zf_C2H2_ZHX PF18387.1 KFQ97321.1 - 0.4 10.3 0.0 0.4 10.3 0.0 5.4 5 1 1 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_9 PF16293.5 KFQ97321.1 - 2.8 7.8 12.1 0.13 12.1 0.2 4.3 5 0 0 5 5 5 0 C2H2 type zinc-finger (1 copy) PB1 PF00564.24 KFQ97323.1 - 7.2e-13 48.3 0.0 1.2e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 PB1 domain PDZ PF00595.24 KFQ97323.1 - 3.3e-11 43.4 0.0 6.1e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFQ97323.1 - 2.7e-08 33.5 0.1 5.3e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Y_phosphatase PF00102.27 KFQ97324.1 - 5.8e-80 268.2 0.0 8e-80 267.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFQ97324.1 - 9.4e-05 22.2 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFQ97324.1 - 0.0063 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFQ97324.1 - 0.042 14.0 0.1 0.17 12.0 0.1 2.2 1 1 0 1 1 1 0 Inositol hexakisphosphate bZIP_2 PF07716.15 KFQ97325.1 - 2.4e-18 65.9 12.9 3.3e-18 65.5 12.9 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KFQ97325.1 - 0.0001 22.3 11.8 0.00017 21.6 11.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor CCD48 PF15799.5 KFQ97325.1 - 0.00012 20.5 1.4 0.0002 19.8 1.4 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 bZIP_Maf PF03131.17 KFQ97325.1 - 0.26 11.8 6.8 0.4 11.2 6.8 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor DivIC PF04977.15 KFQ97325.1 - 0.44 10.4 2.6 0.75 9.6 2.6 1.3 1 0 0 1 1 1 0 Septum formation initiator TMEM189_B_dmain PF10520.9 KFQ97326.1 - 8e-29 101.0 2.1 1.2e-28 100.4 2.1 1.3 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain UQ_con PF00179.26 KFQ97326.1 - 6.5e-18 64.7 0.0 1e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFQ97326.1 - 0.038 14.3 0.0 0.052 13.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain zf-C2H2 PF00096.26 KFQ97327.1 - 1.3e-24 85.3 31.6 5.8e-06 26.5 0.7 5.2 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ97327.1 - 9.1e-19 66.6 32.1 0.00012 22.6 1.4 5.2 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ97327.1 - 3e-14 52.8 18.7 0.00044 20.4 0.2 5.4 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KFQ97327.1 - 1.3e-13 50.7 38.4 3e-07 30.5 0.5 5.9 5 2 0 5 5 5 3 Zinc-finger double domain zf-met PF12874.7 KFQ97327.1 - 3.7e-09 36.7 17.7 0.0031 17.8 0.8 4.4 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFQ97327.1 - 4.6e-08 32.9 33.7 0.0015 18.4 1.2 5.5 5 1 0 5 5 5 4 C2H2-type zinc finger zf-C2HE PF16278.5 KFQ97327.1 - 7.5e-07 29.5 23.8 0.023 15.1 0.7 4.9 1 1 4 5 5 5 3 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 KFQ97327.1 - 0.0041 17.4 22.6 0.98 9.8 1.0 4.9 1 1 3 4 4 4 2 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 KFQ97327.1 - 0.007 17.1 1.0 0.007 17.1 1.0 3.0 2 1 0 2 2 1 1 zinc-ribbon family Zn-ribbon_8 PF09723.10 KFQ97327.1 - 0.0099 16.0 21.0 0.23 11.6 0.8 4.3 1 1 4 5 5 5 3 Zinc ribbon domain zf-BED PF02892.15 KFQ97327.1 - 0.015 15.3 27.6 0.11 12.6 0.7 5.1 2 2 3 5 5 5 0 BED zinc finger zf-C2HC_2 PF13913.6 KFQ97327.1 - 0.016 15.1 13.6 0.64 10.0 0.6 4.5 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-AN1 PF01428.16 KFQ97327.1 - 0.02 15.0 21.0 3.4 7.9 1.7 5.2 5 0 0 5 5 5 0 AN1-like Zinc finger PyrI_C PF02748.15 KFQ97327.1 - 0.077 12.9 15.3 0.85 9.6 2.1 4.7 5 0 0 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_11 PF16622.5 KFQ97327.1 - 0.79 9.5 27.8 5.2 6.9 0.6 5.2 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-CHY PF05495.12 KFQ97327.1 - 1.4 9.5 27.0 1.2 9.6 6.2 2.6 1 1 1 2 2 2 0 CHY zinc finger Spt46 PF17734.1 KFQ97327.1 - 2.1 8.1 16.5 1.1 9.1 4.4 3.6 1 1 2 4 4 4 0 Spermatogenesis-associated protein 46 DUF2180 PF09947.9 KFQ97327.1 - 2.4 8.2 8.8 0.78 9.8 2.6 2.7 3 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) zf_ZIC PF18366.1 KFQ97327.1 - 4.5 7.5 15.0 4.6 7.4 1.6 4.7 1 1 4 5 5 5 0 Zic proteins zinc finger domain Zn_Tnp_IS1595 PF12760.7 KFQ97327.1 - 4.5 7.3 28.5 2.5 8.2 0.6 3.8 3 1 0 3 3 3 0 Transposase zinc-ribbon domain XPA_N PF01286.18 KFQ97327.1 - 5 7.3 15.5 3.5 7.7 0.1 4.7 5 0 0 5 5 5 0 XPA protein N-terminal Sprouty PF05210.13 KFQ97327.1 - 5.5 7.4 18.2 0.41 11.1 2.0 2.7 2 1 0 2 2 2 0 Sprouty protein (Spry) zf-Di19 PF05605.12 KFQ97328.1 - 2.3e-18 66.2 2.4 2.3e-18 66.2 2.4 3.2 2 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf_C2HC_14 PF18574.1 KFQ97328.1 - 1.3e-15 56.9 6.7 1.3e-15 56.9 6.7 2.2 2 0 0 2 2 2 1 C2HC Zing finger domain zf-C2H2_4 PF13894.6 KFQ97328.1 - 0.025 15.4 1.1 0.025 15.4 1.1 4.9 5 1 0 5 5 5 0 C2H2-type zinc finger DND1_DSRM PF14709.7 KFQ97328.1 - 0.027 14.7 0.0 0.074 13.3 0.0 1.8 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 zf-RRN7 PF11781.8 KFQ97328.1 - 0.034 13.8 7.5 0.85 9.4 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 tRNA-synt_1g PF09334.11 KFQ97328.1 - 0.33 9.7 4.5 0.66 8.7 4.2 1.8 1 1 1 2 2 2 0 tRNA synthetases class I (M) DZR PF12773.7 KFQ97328.1 - 0.33 11.0 17.4 2.8 8.0 8.2 2.7 2 1 0 2 2 2 0 Double zinc ribbon zf_UBZ PF18439.1 KFQ97328.1 - 6.2 6.5 9.1 2.8 7.6 0.0 3.8 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-B_box PF00643.24 KFQ97329.1 - 2.3 8.4 17.8 1.3 9.2 4.4 3.1 2 1 0 2 2 2 0 B-box zinc finger Na_H_Exchanger PF00999.21 KFQ97330.1 - 5.4e-63 213.1 39.6 6.5e-63 212.8 39.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Glyco_transf_7N PF13733.6 KFQ97331.1 - 9e-56 187.2 0.0 1.4e-55 186.6 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 KFQ97331.1 - 4.4e-29 100.0 0.4 7.6e-29 99.2 0.4 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Staufen_C PF16482.5 KFQ97332.1 - 3.4e-55 185.0 2.0 2.1e-49 166.3 0.0 5.0 5 0 0 5 5 5 3 Staufen C-terminal domain dsrm PF00035.26 KFQ97332.1 - 2.3e-48 162.8 3.8 2.2e-12 47.5 0.0 4.9 5 0 0 5 5 5 4 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KFQ97332.1 - 8.8e-07 29.1 7.0 0.24 11.7 0.0 5.4 5 2 0 5 5 5 3 double strand RNA binding domain from DEAD END PROTEIN 1 LPP20 PF02169.16 KFQ97332.1 - 0.043 14.2 0.1 6.2 7.3 0.0 3.3 3 0 0 3 3 3 0 LPP20 lipoprotein CAS_CSE1 PF03378.15 KFQ97333.1 - 2.8e-176 586.4 5.8 3.6e-176 586.0 3.6 2.1 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KFQ97333.1 - 1.9e-168 560.0 5.3 4e-168 559.0 5.3 1.6 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 KFQ97333.1 - 1.3e-10 41.0 0.1 8.8e-10 38.4 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KFQ97333.1 - 0.012 15.6 0.0 0.012 15.6 0.0 4.0 4 1 0 5 5 5 0 Exportin 1-like protein PUF PF00806.19 KFQ97333.1 - 0.051 13.3 0.0 1.2 8.9 0.0 3.1 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat DUF3385 PF11865.8 KFQ97333.1 - 0.21 11.5 2.8 0.42 10.5 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Sec7 PF01369.20 KFQ97334.1 - 5.6e-72 241.3 0.7 1.5e-71 239.9 0.7 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KFQ97334.1 - 4e-51 173.0 3.4 1.1e-50 171.6 2.2 2.5 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KFQ97334.1 - 1.4e-37 129.1 0.2 2.6e-36 125.0 0.1 2.9 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 KFQ97334.1 - 1.7e-34 117.5 0.1 1.7e-34 117.5 0.1 5.7 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) Cmyb_C PF09316.10 KFQ97335.1 - 5.3e-65 218.1 4.4 1.3e-64 216.8 4.4 1.7 1 0 0 1 1 1 1 C-myb, C-terminal Myb_DNA-binding PF00249.31 KFQ97335.1 - 3.3e-50 168.1 17.3 3.3e-17 62.4 3.2 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFQ97335.1 - 1.1e-43 147.3 12.4 6e-19 68.1 1.0 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFQ97335.1 - 9.8e-08 31.8 5.4 0.006 16.4 0.0 3.5 2 1 1 3 3 3 3 Myb DNA-binding like SLIDE PF09111.10 KFQ97335.1 - 3.9e-06 26.9 1.4 0.55 10.3 0.0 3.4 1 1 2 3 3 3 3 SLIDE Sigma70_r4_2 PF08281.12 KFQ97335.1 - 0.0013 18.3 0.0 0.003 17.2 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 SANT_DAMP1_like PF16282.5 KFQ97335.1 - 0.0087 16.2 5.6 1.8 8.8 0.1 3.5 1 1 2 3 3 3 1 SANT/Myb-like domain of DAMP1 SbcD_C PF12320.8 KFQ97335.1 - 0.024 14.9 0.3 0.059 13.7 0.0 1.8 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Rap1_C PF11626.8 KFQ97335.1 - 0.045 13.8 6.5 3.1 7.9 1.4 3.6 1 1 2 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Atg29_N PF18388.1 KFQ97335.1 - 0.13 12.1 0.6 0.71 9.7 0.0 2.4 2 0 0 2 2 2 0 Atg29 N-terminal domain Myb_DNA-bind_2 PF08914.11 KFQ97335.1 - 7.6 6.8 6.8 19 5.5 0.2 3.4 1 1 2 3 3 3 0 Rap1 Myb domain ABC_transp_aux PF09822.9 KFQ97337.1 - 6.7e-09 35.6 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DDOST_48kD PF03345.14 KFQ97337.1 - 0.0012 17.8 0.0 0.077 11.8 0.0 2.1 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Pkinase PF00069.25 KFQ97338.1 - 1e-68 231.6 0.0 1.2e-68 231.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ97338.1 - 3.6e-35 121.5 0.0 4.5e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KFQ97338.1 - 3.5e-06 27.6 0.2 6.9e-06 26.7 0.2 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFQ97338.1 - 1.4e-05 24.6 0.1 4.9e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFQ97338.1 - 0.0012 18.2 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KFQ97338.1 - 0.0078 15.9 0.0 0.63 9.6 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Aa_trans PF01490.18 KFQ97339.1 - 1.9e-99 333.2 19.1 2.3e-99 332.9 19.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RhoGAP PF00620.27 KFQ97340.1 - 1.6e-43 148.1 3.9 6e-43 146.3 0.3 2.4 2 0 0 2 2 2 1 RhoGAP domain ERK-JNK_inhib PF15002.6 KFQ97340.1 - 0.026 14.2 1.1 0.057 13.1 1.1 1.5 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor USP7_C2 PF14533.6 KFQ97340.1 - 0.043 13.5 0.1 0.17 11.6 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin-specific protease C-terminal Leukocidin PF07968.12 KFQ97340.1 - 0.06 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Leukocidin/Hemolysin toxin family Actin PF00022.19 KFQ97341.1 - 4.7e-44 150.6 0.0 2.1e-25 89.2 0.0 2.2 2 0 0 2 2 2 2 Actin DUF1542 PF07564.11 KFQ97341.1 - 0.013 15.5 2.6 0.085 13.0 0.2 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) DUF2777 PF10949.8 KFQ97341.1 - 0.069 12.8 1.5 0.13 11.9 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) GH-E PF14410.6 KFQ97341.1 - 0.12 12.7 0.4 0.38 11.2 0.4 1.8 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Sushi PF00084.20 KFQ97346.1 - 5.2e-36 123.0 14.1 4.4e-13 49.6 0.6 3.0 3 0 0 3 3 3 3 Sushi repeat (SCR repeat) HRM PF02793.22 KFQ97346.1 - 0.00031 21.0 7.0 0.14 12.5 0.2 3.4 2 1 1 3 3 3 2 Hormone receptor domain cEGF PF12662.7 KFQ97346.1 - 0.01 15.8 4.2 9 6.3 0.0 3.8 3 1 0 3 3 3 0 Complement Clr-like EGF-like CBM_14 PF01607.24 KFQ97346.1 - 0.2 11.8 5.1 8.9 6.6 0.5 2.9 3 0 0 3 3 3 0 Chitin binding Peritrophin-A domain Sushi PF00084.20 KFQ97347.1 - 1.6e-68 227.2 39.2 6.3e-12 45.9 0.3 7.1 7 0 0 7 7 7 7 Sushi repeat (SCR repeat) cEGF PF12662.7 KFQ97347.1 - 5.6e-06 26.2 20.3 1.1 9.2 0.1 7.5 7 0 0 7 7 7 5 Complement Clr-like EGF-like Sushi PF00084.20 KFQ97348.1 - 4e-15 56.1 0.2 1.1e-10 41.9 0.1 2.0 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) Sushi PF00084.20 KFQ97349.1 - 8.1e-65 215.3 31.2 3.4e-13 50.0 2.0 6.2 6 0 0 6 6 6 6 Sushi repeat (SCR repeat) C4bp_oligo PF18453.1 KFQ97349.1 - 0.0089 16.2 2.1 0.02 15.1 1.2 2.0 2 0 0 2 2 2 1 Oligomerization domain of C4b-binding protein alpha HRM PF02793.22 KFQ97349.1 - 0.24 11.7 26.1 0.36 11.2 1.1 5.9 4 2 1 5 5 5 0 Hormone receptor domain 6PF2K PF01591.18 KFQ97350.1 - 1.7e-101 338.2 1.3 2.4e-101 337.7 1.3 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KFQ97350.1 - 8e-42 143.1 0.0 1e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KFQ97350.1 - 7.3e-08 32.7 0.0 1.8e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KFQ97350.1 - 5.9e-05 22.7 0.2 0.00011 21.8 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_17 PF13207.6 KFQ97350.1 - 0.0047 17.4 0.0 0.012 16.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain His_Phos_2 PF00328.22 KFQ97350.1 - 0.046 13.1 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) APS_kinase PF01583.20 KFQ97350.1 - 0.15 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase OTU PF02338.19 KFQ97351.1 - 1.9e-05 25.1 0.0 3.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease zf-C2H2_2 PF12756.7 KFQ97351.1 - 0.061 13.7 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) IL10 PF00726.17 KFQ97352.1 - 5.2e-05 22.8 0.1 6.3e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Interleukin 10 IL22 PF14565.6 KFQ97352.1 - 0.0073 16.6 0.9 0.87 9.9 0.2 2.2 1 1 1 2 2 2 2 Interleukin 22 IL-10-related T-cell-derived-inducible factor Phospholip_A2_2 PF05826.12 KFQ97352.1 - 0.0094 16.2 0.5 0.015 15.5 0.5 1.3 1 0 0 1 1 1 1 Phospholipase A2 Pkinase PF00069.25 KFQ97353.1 - 2.2e-58 197.7 0.1 4.5e-58 196.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ97353.1 - 3.4e-21 75.7 0.2 7.6e-21 74.6 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFQ97353.1 - 2e-05 24.6 0.0 0.0029 17.6 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KFQ97353.1 - 0.0029 17.2 2.3 0.0031 17.1 0.4 1.9 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 KFQ97353.1 - 0.004 16.8 1.6 0.0073 15.9 1.6 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 KFQ97353.1 - 0.004 16.7 1.2 0.16 11.5 0.0 2.4 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.14 KFQ97353.1 - 0.016 14.6 0.2 0.033 13.5 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Staphylcoagulse PF04022.12 KFQ97353.1 - 0.066 12.8 0.5 0.15 11.6 0.5 1.5 1 0 0 1 1 1 0 Staphylocoagulase repeat Pre-PUA PF17832.1 KFQ97354.1 - 1.5e-20 73.7 0.3 6.7e-20 71.6 0.1 2.3 2 0 0 2 2 2 1 Pre-PUA-like domain SUI1 PF01253.22 KFQ97354.1 - 1.7e-20 73.3 0.3 3.3e-20 72.4 0.3 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 PUA PF01472.20 KFQ97354.1 - 1.3e-05 25.0 0.2 8.4e-05 22.5 0.1 2.1 2 0 0 2 2 2 1 PUA domain SWIB PF02201.18 KFQ97354.1 - 0.0026 17.6 0.1 0.0078 16.1 0.1 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain Nore1-SARAH PF16517.5 KFQ97355.1 - 1.3e-18 66.6 5.1 1.3e-18 66.6 5.1 2.3 2 0 0 2 2 2 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain RA PF00788.23 KFQ97355.1 - 5.2e-17 62.3 0.0 2.5e-16 60.1 0.0 2.1 1 1 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Mst1_SARAH PF11629.8 KFQ97355.1 - 4.3 7.5 7.3 0.5 10.5 0.7 2.6 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 Pkinase PF00069.25 KFQ97356.1 - 6.1e-48 163.5 0.0 9.3e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TBK1_ULD PF18396.1 KFQ97356.1 - 2e-32 110.9 1.1 3.5e-32 110.2 1.1 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Pkinase_Tyr PF07714.17 KFQ97356.1 - 2.7e-28 98.9 0.0 4e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TBK1_CCD1 PF18394.1 KFQ97356.1 - 5.2e-11 42.6 0.2 6.8e-08 32.4 0.1 2.2 2 0 0 2 2 2 2 TANK-binding kinase 1 coiled-coil domain 1 Kinase-like PF14531.6 KFQ97356.1 - 0.00014 21.3 0.0 0.013 14.8 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFQ97356.1 - 0.00021 20.2 0.0 0.0062 15.4 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFQ97356.1 - 0.015 15.2 0.0 1.7 8.5 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF4892 PF16234.5 KFQ97356.1 - 0.036 13.5 0.1 0.15 11.5 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4892) FAM72 PF14976.6 KFQ97357.1 - 3.2e-38 131.1 0.2 3.5e-38 131.0 0.2 1.0 1 0 0 1 1 1 1 FAM72 protein 7tm_1 PF00001.21 KFQ97358.1 - 1.2e-51 175.5 8.6 1.5e-51 175.3 8.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ97358.1 - 1.3e-09 37.8 4.9 1.9e-09 37.3 4.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 KFQ97358.1 - 8.9e-06 25.3 0.1 2.1e-05 24.1 0.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFQ97358.1 - 1.3e-05 25.1 2.7 2.1e-05 24.4 2.7 1.3 1 0 0 1 1 1 1 Olfactory receptor Srg PF02118.21 KFQ97358.1 - 0.0097 15.6 4.9 0.0097 15.6 4.9 2.1 2 1 0 2 2 2 1 Srg family chemoreceptor Git3 PF11710.8 KFQ97358.1 - 0.24 11.1 6.6 0.44 10.3 6.6 1.4 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Asp PF00026.23 KFQ97359.1 - 1.4e-121 405.8 0.3 1.6e-121 405.5 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFQ97359.1 - 3.3e-15 56.8 2.2 2.3e-11 44.3 0.3 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal A1_Propeptide PF07966.12 KFQ97359.1 - 1.6e-07 31.0 0.3 2.4e-07 30.5 0.3 1.3 1 0 0 1 1 1 1 A1 Propeptide Asp_protease_2 PF13650.6 KFQ97359.1 - 0.0075 16.9 0.3 5.4 7.7 0.1 3.2 2 2 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KFQ97359.1 - 0.099 12.4 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Ras PF00071.22 KFQ97360.1 - 1.5e-32 112.5 0.0 1.6e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ97360.1 - 1.9e-12 47.4 0.0 2.7e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ97360.1 - 2.9e-08 33.4 0.0 3.1e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFQ97360.1 - 0.0035 16.9 0.0 0.014 14.9 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 KFQ97360.1 - 0.088 12.8 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Sulfate_transp PF00916.20 KFQ97361.1 - 1.4e-92 310.4 22.2 2e-92 309.9 22.2 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFQ97361.1 - 1.6e-25 89.0 0.0 2.6e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain Peptidase_M20 PF01546.28 KFQ97362.1 - 1.3e-32 113.2 0.0 2.1e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFQ97362.1 - 4.7e-16 58.6 0.0 1e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Ntox3 PF15536.6 KFQ97362.1 - 0.022 14.8 0.0 0.039 14.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial toxin 3 MgtE PF01769.16 KFQ97363.1 - 3.4e-55 185.7 24.9 1.2e-30 106.4 3.5 2.8 3 0 0 3 3 3 2 Divalent cation transporter MFS_1 PF07690.16 KFQ97365.1 - 1.2e-13 50.8 32.6 2.1e-13 50.0 24.0 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFQ97365.1 - 4.2e-07 28.9 2.7 4.2e-07 28.9 2.7 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein PUCC PF03209.15 KFQ97365.1 - 0.004 16.2 1.0 0.004 16.2 1.0 2.1 3 0 0 3 3 3 1 PUCC protein DUF553 PF04473.12 KFQ97365.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like domain Ets PF00178.22 KFQ97367.1 - 5.5e-36 122.9 1.8 8.4e-36 122.3 1.8 1.3 1 0 0 1 1 1 1 Ets-domain MFS_1 PF07690.16 KFQ97368.1 - 3.2e-11 42.7 57.5 5.9e-07 28.7 21.1 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 KFQ97369.1 - 6.7e-69 232.2 0.0 8.2e-69 231.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ97369.1 - 3.7e-33 114.9 0.0 5.3e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ97369.1 - 1.5e-05 24.5 0.0 2.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFQ97369.1 - 8.2e-05 21.7 0.1 0.00027 20.0 0.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFQ97369.1 - 0.0023 17.3 0.1 0.0052 16.2 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KFQ97369.1 - 0.072 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KFQ97369.1 - 0.093 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kelch_1 PF01344.25 KFQ97370.1 - 4.8e-49 163.7 0.9 5.9e-10 38.6 0.0 7.1 7 0 0 7 7 7 7 Kelch motif Kelch_6 PF13964.6 KFQ97370.1 - 7.9e-37 124.4 0.9 1.1e-07 31.9 0.0 7.1 3 3 4 7 7 7 7 Kelch motif Kelch_2 PF07646.15 KFQ97370.1 - 9.7e-22 76.1 0.0 4.9e-05 23.1 0.0 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KFQ97370.1 - 2e-21 75.7 0.3 5.5e-06 26.3 0.0 6.3 6 1 1 7 7 7 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KFQ97370.1 - 6.2e-18 64.6 0.2 0.00098 19.4 0.1 5.9 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFQ97370.1 - 3.6e-10 39.6 1.0 0.0051 16.8 0.0 5.3 6 0 0 6 6 6 2 Kelch motif WYL_2 PF10902.8 KFQ97370.1 - 0.0072 16.7 0.2 5.1 7.5 0.0 3.4 4 0 0 4 4 4 1 WYL_2, Sm-like SH3 beta-barrel fold Pkinase PF00069.25 KFQ97371.1 - 5.4e-68 229.2 0.1 8.3e-68 228.6 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ97371.1 - 1.9e-38 132.2 0.0 2.8e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFQ97371.1 - 8.7e-07 28.2 0.4 1.4e-06 27.5 0.4 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFQ97371.1 - 8.9e-07 28.5 0.0 1.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFQ97371.1 - 1.7e-05 24.5 0.9 2.8e-05 23.8 0.9 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KFQ97371.1 - 0.00012 21.5 0.3 0.0002 20.8 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFQ97371.1 - 0.0019 18.1 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Tmemb_cc2 PF10267.9 KFQ97372.1 - 3.3e-178 592.9 6.9 5.1e-178 592.3 6.9 1.3 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein LMBR1 PF04791.16 KFQ97372.1 - 0.00015 20.8 3.8 0.0012 17.9 0.4 2.1 2 0 0 2 2 2 1 LMBR1-like membrane protein 7TMR-HDED PF07697.11 KFQ97372.1 - 0.0016 18.6 12.3 0.19 11.8 0.2 2.4 2 0 0 2 2 2 2 7TM-HD extracellular TraG_N PF07916.11 KFQ97372.1 - 0.0019 17.1 0.5 0.0045 15.9 0.5 1.5 1 0 0 1 1 1 1 TraG-like protein, N-terminal region Exonuc_VII_L PF02601.15 KFQ97372.1 - 0.0031 17.1 16.5 0.18 11.4 0.6 2.3 2 0 0 2 2 2 2 Exonuclease VII, large subunit AI-2E_transport PF01594.16 KFQ97372.1 - 0.017 14.3 5.8 5.2 6.1 0.0 2.9 3 0 0 3 3 3 0 AI-2E family transporter DUF1479 PF07350.12 KFQ97372.1 - 0.054 12.2 4.5 0.12 11.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) GET2 PF08690.10 KFQ97372.1 - 0.06 13.0 0.2 0.06 13.0 0.2 2.6 2 1 0 2 2 2 0 GET complex subunit GET2 Atg14 PF10186.9 KFQ97372.1 - 0.074 12.1 20.8 0.061 12.4 4.4 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2313 PF10076.9 KFQ97372.1 - 0.074 12.9 5.3 0.046 13.6 0.6 2.4 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2313) Prominin PF05478.11 KFQ97372.1 - 0.097 10.6 20.7 0.12 10.3 10.5 2.4 2 1 0 2 2 2 0 Prominin Lipoprotein_20 PF13942.6 KFQ97372.1 - 0.51 10.2 17.3 0.97 9.3 1.5 2.5 2 1 0 2 2 2 0 YfhG lipoprotein CorA PF01544.18 KFQ97372.1 - 0.8 9.0 14.3 0.64 9.3 4.3 2.7 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein UPF0565 PF10561.9 KFQ97372.1 - 0.82 8.8 5.8 0.18 11.0 0.3 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 Baculo_PEP_C PF04513.12 KFQ97372.1 - 1.2 9.2 13.9 0.053 13.6 1.5 3.5 2 2 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1690 PF07956.11 KFQ97372.1 - 1.3 9.4 22.3 3.2 8.2 5.0 2.7 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) OmpH PF03938.14 KFQ97372.1 - 5.3 7.4 36.8 28 5.1 18.5 3.3 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) CortBP2 PF09727.9 KFQ97372.1 - 8.1 6.3 28.0 0.47 10.3 14.8 2.5 2 0 0 2 2 2 0 Cortactin-binding protein-2 Phage_GPO PF05929.11 KFQ97372.1 - 9.3 5.8 22.8 0.53 9.9 4.4 3.5 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase AAA_11 PF13086.6 KFQ97372.1 - 9.7 5.9 12.6 4.5 7.0 2.7 2.4 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 KFQ97373.1 - 6e-37 127.4 0.0 1.6e-36 126.0 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ97373.1 - 1.1e-35 123.2 0.0 1.9e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFQ97373.1 - 3.6e-05 22.7 0.0 6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFQ97373.1 - 0.0001 21.8 0.0 0.0002 20.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFQ97373.1 - 0.00038 19.5 0.0 0.00096 18.2 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFQ97373.1 - 0.002 17.5 0.7 0.0042 16.5 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFQ97373.1 - 0.12 12.3 2.5 0.3 11.0 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family WD40 PF00400.32 KFQ97374.1 - 8.2e-11 42.3 17.2 0.00036 21.3 2.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ97374.1 - 2.8e-09 37.1 0.7 0.026 14.8 0.0 4.0 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KFQ97374.1 - 0.12 10.6 0.1 0.2 10.0 0.1 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz BUD22 PF09073.10 KFQ97374.1 - 2.2 7.5 11.7 3.3 6.9 11.7 1.2 1 0 0 1 1 1 0 BUD22 Ig_2 PF13895.6 KFQ97375.1 - 0.00024 21.4 0.0 0.00048 20.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFQ97375.1 - 0.0013 18.9 0.0 0.0037 17.4 0.0 1.7 1 1 1 2 2 2 1 Immunoglobulin V-set domain ig PF00047.25 KFQ97375.1 - 0.0089 16.2 0.6 0.019 15.2 0.0 1.9 2 1 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 KFQ97375.1 - 0.02 15.5 0.0 0.042 14.4 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Ig_6 PF18452.1 KFQ97375.1 - 0.021 14.4 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Izumo-Ig PF16706.5 KFQ97375.1 - 0.038 14.1 0.0 0.084 13.0 0.0 1.6 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain TSP_1 PF00090.19 KFQ97375.1 - 0.64 10.3 5.1 1.2 9.4 5.1 1.5 1 0 0 1 1 1 0 Thrombospondin type 1 domain Ig_3 PF13927.6 KFQ97376.1 - 5.5e-76 251.2 0.1 1.9e-12 47.6 0.0 7.3 7 0 0 7 7 7 6 Immunoglobulin domain I-set PF07679.16 KFQ97376.1 - 4e-69 228.7 0.0 6.6e-16 58.2 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.6 KFQ97376.1 - 1.6e-54 182.1 0.0 1e-10 41.8 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.25 KFQ97376.1 - 1.9e-51 172.2 0.1 1.3e-08 34.9 0.0 6.9 7 0 0 7 7 6 6 Immunoglobulin domain fn3 PF00041.21 KFQ97376.1 - 1.9e-48 162.7 3.8 1.5e-17 63.7 0.0 4.5 4 0 0 4 4 4 4 Fibronectin type III domain V-set PF07686.17 KFQ97376.1 - 3e-22 78.9 5.5 0.0062 16.7 0.0 9.3 6 4 1 7 7 7 5 Immunoglobulin V-set domain Ig_5 PF16681.5 KFQ97376.1 - 1.9e-13 50.6 0.0 0.19 12.2 0.0 6.5 7 1 0 7 7 6 4 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFQ97376.1 - 4.5e-13 48.5 0.0 0.0028 17.2 0.0 6.1 6 0 0 6 6 6 2 Immunoglobulin domain Ig_4 PF16680.5 KFQ97376.1 - 2.3e-11 43.8 0.0 0.16 12.3 0.0 5.5 5 0 0 5 5 5 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFQ97376.1 - 8.4e-09 35.4 0.1 0.093 12.8 0.0 5.5 6 0 0 6 6 5 1 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 KFQ97376.1 - 2.5e-08 33.8 0.2 0.9 9.6 0.0 6.2 6 0 0 6 6 6 2 C17orf99 Ig domain Pur_ac_phosph_N PF16656.5 KFQ97376.1 - 9.2e-08 32.6 0.1 0.00048 20.6 0.1 3.5 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain C2-set_2 PF08205.12 KFQ97376.1 - 8e-06 25.8 1.0 0.056 13.5 0.0 4.9 5 0 0 5 5 5 1 CD80-like C2-set immunoglobulin domain C2-set PF05790.15 KFQ97376.1 - 0.002 18.3 0.1 9.9 6.4 0.0 4.9 5 0 0 5 5 5 1 Immunoglobulin C2-set domain Adeno_E3_CR1 PF02440.15 KFQ97376.1 - 0.0092 15.7 0.1 5.9 6.7 0.0 3.7 3 0 0 3 3 3 1 Adenovirus E3 region protein CR1 Interfer-bind PF09294.10 KFQ97376.1 - 0.012 15.9 0.0 0.078 13.3 0.0 2.2 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III Ig_3 PF13927.6 KFQ97377.1 - 3.8e-76 251.7 0.2 4.3e-14 52.9 0.0 7.7 7 0 0 7 7 7 6 Immunoglobulin domain I-set PF07679.16 KFQ97377.1 - 1.4e-70 233.4 0.0 2.5e-13 49.9 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.6 KFQ97377.1 - 2.2e-49 165.7 0.0 9.7e-10 38.7 0.0 6.9 7 0 0 7 7 6 6 Immunoglobulin domain ig PF00047.25 KFQ97377.1 - 6.7e-46 154.4 0.0 3.3e-09 36.8 0.0 6.8 6 0 0 6 6 6 6 Immunoglobulin domain fn3 PF00041.21 KFQ97377.1 - 1.5e-44 150.3 16.7 4.7e-12 46.1 0.1 5.7 5 0 0 5 5 5 5 Fibronectin type III domain Bravo_FIGEY PF13882.6 KFQ97377.1 - 9.3e-27 94.2 5.9 3.1e-26 92.5 5.9 2.0 1 0 0 1 1 1 1 Bravo-like intracellular region V-set PF07686.17 KFQ97377.1 - 7.8e-16 58.2 9.2 0.00049 20.2 0.0 10.4 7 5 2 9 9 9 2 Immunoglobulin V-set domain Ig_6 PF18452.1 KFQ97377.1 - 4.9e-10 38.8 0.0 0.15 11.7 0.0 5.9 6 0 0 6 6 6 2 Immunoglobulin domain C2-set_2 PF08205.12 KFQ97377.1 - 9.8e-10 38.4 0.9 0.15 12.1 0.0 6.2 6 2 1 7 7 7 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFQ97377.1 - 2.1e-09 37.7 0.3 0.027 14.9 0.0 5.4 6 1 0 6 6 6 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFQ97377.1 - 2.8e-07 30.7 5.8 0.88 9.9 0.0 6.4 6 1 0 6 6 6 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFQ97377.1 - 0.00063 19.8 0.1 8.1 6.6 0.0 4.4 4 0 0 4 4 3 1 Izumo-like Immunoglobulin domain V-set_CD47 PF08204.11 KFQ97377.1 - 0.0059 16.6 1.7 6.9 6.7 0.0 3.9 4 1 0 4 4 4 1 CD47 immunoglobulin-like domain LRR_8 PF13855.6 KFQ97378.1 - 1.7e-67 223.1 91.6 3.8e-15 55.4 8.1 6.6 1 1 7 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 KFQ97378.1 - 1.7e-24 85.4 47.0 1.1e-05 25.7 3.3 8.3 2 1 5 9 9 9 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFQ97378.1 - 4.9e-22 78.3 0.0 1.3e-09 38.0 0.0 3.0 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFQ97378.1 - 8.8e-15 54.6 18.4 9.5e-05 22.0 2.1 4.6 1 1 4 5 5 5 5 Leucine-rich repeat I-set PF07679.16 KFQ97378.1 - 9e-14 51.3 0.0 1.7e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ97378.1 - 3.4e-11 43.6 0.0 7.7e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFQ97378.1 - 2.3e-06 27.8 0.0 4.6e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFQ97378.1 - 5.1e-06 26.6 0.0 9.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.33 KFQ97378.1 - 1e-05 25.4 33.0 0.059 13.9 0.3 10.3 10 1 0 10 10 10 2 Leucine Rich Repeat V-set PF07686.17 KFQ97378.1 - 0.0013 18.9 0.0 0.01 16.0 0.0 2.2 1 1 0 1 1 1 1 Immunoglobulin V-set domain LRRCT PF01463.24 KFQ97378.1 - 0.035 14.7 1.0 0.23 12.1 0.2 3.0 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain LRRNT PF01462.18 KFQ97378.1 - 1.3 8.8 7.5 0.13 12.0 1.7 2.5 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain zf-C3HC4_3 PF13920.6 KFQ97379.1 - 6.7e-11 41.9 6.5 6.7e-11 41.9 6.5 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SWIB PF02201.18 KFQ97379.1 - 3.6e-06 26.8 0.0 7.8e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain zf-RanBP PF00641.18 KFQ97379.1 - 2.2e-05 23.7 8.8 2.2e-05 23.7 8.8 2.3 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others DZR PF12773.7 KFQ97379.1 - 0.88 9.6 17.7 1.3 9.1 2.4 3.0 2 0 0 2 2 2 0 Double zinc ribbon DUF4099 PF13351.6 KFQ97380.1 - 0.045 14.0 0.0 0.055 13.7 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4099) PP1c_bdg PF10488.9 KFQ97381.1 - 1.9e-128 428.0 11.4 2.1e-128 427.8 11.4 1.0 1 0 0 1 1 1 1 Phosphatase-1 catalytic subunit binding region SDA1 PF05285.12 KFQ97381.1 - 0.075 12.5 10.3 0.095 12.1 10.3 1.2 1 0 0 1 1 1 0 SDA1 VEFS-Box PF09733.9 KFQ97381.1 - 0.28 11.0 9.4 0.6 9.9 1.3 2.3 2 0 0 2 2 2 0 VEFS-Box of polycomb protein DCA16 PF15349.6 KFQ97381.1 - 4.2 6.9 6.6 7.1 6.1 6.6 1.4 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 Got1 PF04178.12 KFQ97382.1 - 6.2e-17 62.0 18.0 7.1e-17 61.9 18.0 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Asp PF00026.23 KFQ97383.1 - 2.3e-112 375.5 0.0 2.6e-112 375.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFQ97383.1 - 2e-10 41.2 0.1 1.4e-08 35.2 0.1 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KFQ97383.1 - 6.9e-05 22.7 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Choline_kinase PF01633.20 KFQ97384.1 - 3e-59 200.2 0.0 4.1e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KFQ97384.1 - 7.5e-13 48.9 0.0 9.7e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFQ97384.1 - 0.0005 19.5 0.7 0.0016 17.8 0.1 1.8 1 1 0 2 2 2 1 Ecdysteroid kinase HMG_box PF00505.19 KFQ97385.1 - 1e-22 80.3 3.8 2e-22 79.3 3.8 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFQ97385.1 - 3.6e-09 37.1 1.7 3.6e-09 37.1 1.7 2.0 2 0 0 2 2 2 1 HMG-box domain CREPT PF16566.5 KFQ97385.1 - 0.3 11.2 12.1 0.058 13.6 7.9 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour LSM PF01423.22 KFQ97386.1 - 4.2e-18 64.8 0.3 4.5e-18 64.7 0.3 1.0 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KFQ97386.1 - 0.0078 15.8 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Hfq protein Cation_ATPase_C PF00689.21 KFQ97387.1 - 1.4e-44 152.0 4.1 5.6e-44 150.0 1.4 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KFQ97387.1 - 2.4e-35 121.7 14.6 9.6e-27 93.7 2.0 2.9 3 0 0 3 3 3 2 E1-E2 ATPase ATP_Ca_trans_C PF12424.8 KFQ97387.1 - 3.2e-27 94.7 0.1 1.2e-26 92.9 0.1 2.1 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal Cation_ATPase PF13246.6 KFQ97387.1 - 2.7e-20 72.3 0.0 6.3e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFQ97387.1 - 2.1e-15 56.2 0.0 8e-15 54.3 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KFQ97387.1 - 4.1e-14 53.4 0.5 8.6e-13 49.1 0.5 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFQ97387.1 - 7.2e-05 22.6 0.1 0.007 16.1 0.1 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Ferlin_C PF16165.5 KFQ97387.1 - 3.8 7.4 5.6 26 4.7 0.0 2.8 2 1 0 2 2 2 0 Ferlin C-terminus Trypan_PARP PF05887.11 KFQ97387.1 - 6.7 6.7 7.4 13 5.7 0.3 3.0 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) LRR_8 PF13855.6 KFQ97388.1 - 1.1e-22 79.6 3.3 4.3e-10 39.2 0.0 4.0 3 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFQ97388.1 - 1.3e-11 44.6 9.7 0.002 18.5 3.9 4.7 1 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFQ97388.1 - 1.3e-05 24.8 0.7 0.011 15.2 0.1 2.2 2 0 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFQ97388.1 - 3.8e-05 23.7 8.7 5.8 7.9 0.3 5.5 5 1 0 5 5 5 3 Leucine Rich Repeat LRRNT PF01462.18 KFQ97388.1 - 0.00016 21.2 4.1 0.00016 21.2 4.1 3.1 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_12 PF18837.1 KFQ97388.1 - 0.00064 19.3 5.8 0.005 16.4 0.0 3.0 3 0 0 3 3 3 1 Leucine-rich repeat LRR_6 PF13516.6 KFQ97388.1 - 0.0014 18.5 3.6 2.8 8.2 0.1 4.6 5 0 0 5 5 5 1 Leucine Rich repeat LRR_5 PF13306.6 KFQ97388.1 - 0.0056 16.6 0.0 0.72 9.8 0.0 2.5 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) CSTF_C PF14304.6 KFQ97388.1 - 1.8 8.2 4.7 19 4.9 0.3 2.6 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal LRR_8 PF13855.6 KFQ97389.1 - 5.6e-39 131.7 38.8 3.1e-12 46.1 9.0 6.4 3 2 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 KFQ97389.1 - 1.9e-26 91.6 37.3 1.8e-06 28.2 4.0 7.1 4 1 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFQ97389.1 - 6.2e-07 29.1 33.2 0.58 10.9 0.1 10.9 10 1 0 10 10 10 2 Leucine Rich Repeat LRR_9 PF14580.6 KFQ97389.1 - 6.7e-07 29.0 16.5 0.0015 18.1 6.2 4.2 1 1 3 4 4 4 3 Leucine-rich repeat LRRNT PF01462.18 KFQ97389.1 - 3.6e-06 26.5 4.4 3.6e-06 26.5 4.4 3.1 4 0 0 4 4 4 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.6 KFQ97389.1 - 4.4e-06 26.7 1.3 0.0037 17.2 0.0 3.1 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) FNIP PF05725.12 KFQ97389.1 - 0.022 14.9 9.6 5.7 7.2 0.1 4.4 2 2 2 4 4 4 0 FNIP Repeat LRR_6 PF13516.6 KFQ97389.1 - 0.023 14.7 25.5 8.3 6.7 0.0 7.8 9 0 0 9 9 9 0 Leucine Rich repeat LRR_8 PF13855.6 KFQ97390.1 - 4.5e-31 106.4 25.0 8.6e-10 38.2 0.2 6.2 3 2 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 KFQ97390.1 - 6e-22 77.4 26.0 6.9e-07 29.5 0.6 7.0 2 2 6 8 8 8 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFQ97390.1 - 3.4e-10 39.7 4.4 0.00027 20.5 0.1 3.9 1 1 3 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 KFQ97390.1 - 5.5e-10 38.4 20.6 0.2 12.3 0.1 9.5 10 1 0 10 10 10 3 Leucine Rich Repeat LRR_6 PF13516.6 KFQ97390.1 - 1.6e-08 33.9 17.5 0.2 11.8 0.0 8.1 8 0 0 8 8 8 4 Leucine Rich repeat LRRNT PF01462.18 KFQ97390.1 - 7.9e-07 28.6 2.0 7.9e-07 28.6 2.0 3.0 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.6 KFQ97390.1 - 9.1e-07 28.9 2.1 0.00012 22.0 0.0 2.6 2 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) FNIP PF05725.12 KFQ97390.1 - 0.00013 22.0 0.4 3.4 7.9 0.0 4.6 2 2 2 4 4 4 2 FNIP Repeat BTG PF07742.12 KFQ97391.1 - 5.6e-39 132.6 0.0 6.7e-39 132.3 0.0 1.1 1 0 0 1 1 1 1 BTG family SHIPPO-rpt PF07004.12 KFQ97392.1 - 0.064 14.2 15.7 0.066 14.2 0.2 4.4 3 2 0 3 3 3 0 Sperm-tail PG-rich repeat ECR1_N PF14382.6 KFQ97392.1 - 0.065 13.0 0.0 0.32 10.8 0.0 2.1 2 0 0 2 2 2 0 Exosome complex exonuclease RRP4 N-terminal region SHIPPO-rpt PF07004.12 KFQ97393.1 - 0.064 14.2 15.7 0.066 14.2 0.2 4.4 3 2 0 3 3 3 0 Sperm-tail PG-rich repeat ECR1_N PF14382.6 KFQ97393.1 - 0.065 13.0 0.0 0.32 10.8 0.0 2.1 2 0 0 2 2 2 0 Exosome complex exonuclease RRP4 N-terminal region Bromo_TP PF07524.13 KFQ97394.1 - 9.4e-31 105.7 0.8 2.4e-30 104.4 0.2 1.8 2 0 0 2 2 2 1 Bromodomain associated TAF8_C PF10406.9 KFQ97394.1 - 1.2e-22 80.2 1.3 3.2e-22 78.8 1.3 1.8 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term TFIID-31kDa PF02291.15 KFQ97394.1 - 2.2e-05 24.5 0.0 3.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP_like PF17027.5 KFQ97394.1 - 0.0003 20.9 0.0 0.00057 20.0 0.0 1.5 1 0 0 1 1 1 1 Histone-fold protein DUF3090 PF11290.8 KFQ97394.1 - 0.0024 17.7 0.4 0.008 16.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3090) CENP-S PF15630.6 KFQ97394.1 - 0.011 16.1 0.1 0.028 14.8 0.0 1.7 2 0 0 2 2 2 0 CENP-S protein CBFD_NFYB_HMF PF00808.23 KFQ97394.1 - 0.047 14.0 0.1 0.092 13.0 0.1 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KFQ97394.1 - 0.097 12.8 0.1 0.27 11.4 0.0 1.8 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KFQ97394.1 - 0.16 12.2 0.3 0.39 10.9 0.1 1.7 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) Type2_restr_D3 PF16902.5 KFQ97394.1 - 0.17 11.8 0.1 57 3.7 0.1 3.6 4 0 0 4 4 4 0 Type-2 restriction enzyme D3 domain Cyclin_N PF00134.23 KFQ97396.1 - 4e-28 97.7 0.8 6.7e-28 97.0 0.8 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFQ97396.1 - 5.9e-20 71.5 1.2 2.2e-19 69.7 0.2 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain K-cyclin_vir_C PF09080.10 KFQ97396.1 - 0.00058 20.3 0.4 0.00098 19.5 0.4 1.3 1 0 0 1 1 1 1 K cyclin, C terminal Herp-Cyclin PF09241.10 KFQ97396.1 - 0.003 18.2 0.1 0.0053 17.4 0.1 1.3 1 0 0 1 1 1 1 Herpesviridae viral cyclin Bystin PF05291.11 KFQ97397.1 - 5.5e-142 472.3 0.2 6.2e-142 472.1 0.2 1.0 1 0 0 1 1 1 1 Bystin NUC130_3NT PF08158.12 KFQ97397.1 - 0.1 12.9 0.1 0.4 11.0 0.1 2.0 1 0 0 1 1 1 0 NUC130/3NT domain Med20 PF08612.11 KFQ97398.1 - 2e-36 125.4 0.0 2.3e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex UCH PF00443.29 KFQ97399.1 - 1.2e-57 195.4 0.2 1.2e-57 195.4 0.2 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFQ97399.1 - 3e-21 75.5 7.1 3e-21 75.5 7.1 2.9 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KFQ97399.1 - 2e-16 60.5 0.2 2e-16 60.5 0.2 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 KFQ97399.1 - 0.038 13.7 0.4 0.038 13.7 0.4 2.5 2 0 0 2 2 2 0 Variant UBP zinc finger Stc1 PF12898.7 KFQ97399.1 - 0.2 12.2 0.1 0.2 12.2 0.1 3.0 3 0 0 3 3 3 0 Stc1 domain ArfGap PF01412.18 KFQ97399.1 - 6.6 6.8 9.6 0.36 10.9 2.5 2.5 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf IRS PF02174.17 KFQ97400.1 - 2.1e-26 91.7 0.0 4.2e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 PTB domain (IRS-1 type) Notch PF00066.17 KFQ97400.1 - 0.038 14.5 7.0 0.11 13.0 7.0 1.8 1 0 0 1 1 1 0 LNR domain MDFI PF15316.6 KFQ97401.1 - 1.5e-48 165.1 42.4 1.7e-48 164.9 42.4 1.0 1 0 0 1 1 1 1 MyoD family inhibitor FOXP-CC PF16159.5 KFQ97402.1 - 1.4e-34 118.5 5.0 1.4e-34 118.5 5.0 2.2 2 0 0 2 2 2 1 FOXP coiled-coil domain Forkhead PF00250.18 KFQ97402.1 - 3.2e-28 97.8 0.1 6e-28 96.9 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain Zap1_zf2 PF18217.1 KFQ97402.1 - 0.02 14.9 0.5 0.041 13.9 0.5 1.6 1 0 0 1 1 1 0 Zap1 zinc finger 2 Bestrophin PF01062.21 KFQ97402.1 - 0.083 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel SIT PF15330.6 KFQ97403.1 - 2.3e-06 28.0 0.1 3.1e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 SHP2-interacting transmembrane adaptor protein, SIT EphA2_TM PF14575.6 KFQ97403.1 - 0.013 16.4 0.1 0.015 16.2 0.1 1.3 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM100 PF16311.5 KFQ97403.1 - 0.044 13.4 0.1 0.071 12.7 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 100 TMEM154 PF15102.6 KFQ97403.1 - 0.051 13.5 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family TAP35_44 PF07265.11 KFQ97403.1 - 0.09 12.8 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 Herpes_gE PF02480.16 KFQ97403.1 - 0.14 10.9 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E V-set PF07686.17 KFQ97404.1 - 5.3e-11 42.7 1.8 7.5e-11 42.2 1.8 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFQ97404.1 - 0.0048 17.0 0.4 0.011 15.9 0.4 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFQ97404.1 - 0.025 15.2 1.1 0.087 13.4 1.1 1.9 1 1 0 1 1 1 0 Immunoglobulin domain Egh16-like PF11327.8 KFQ97404.1 - 0.12 12.7 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Egh16-like virulence factor CBFB_NFYA PF02045.15 KFQ97405.1 - 2.1e-27 95.5 8.7 3.4e-27 94.8 8.7 1.3 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Macro PF01661.21 KFQ97406.1 - 7.4e-08 32.4 0.0 1.1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Macro domain PSII_Pbs27 PF13326.6 KFQ97406.1 - 0.084 13.2 0.0 0.22 11.9 0.0 1.5 1 1 1 2 2 2 0 Photosystem II Pbs27 Il2rg PF15874.5 KFQ97406.1 - 0.12 12.7 0.1 0.16 12.2 0.1 1.1 1 0 0 1 1 1 0 Putative Interleukin 2 receptor, gamma chain TspO_MBR PF03073.15 KFQ97407.1 - 7.2e-48 162.1 9.5 8.1e-48 161.9 9.5 1.0 1 0 0 1 1 1 1 TspO/MBR family Bcl-2 PF00452.19 KFQ97408.1 - 1.8e-25 89.5 1.1 2e-25 89.3 0.0 1.6 2 0 0 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family Bcl-2_3 PF15286.6 KFQ97408.1 - 0.009 16.7 0.1 0.023 15.3 0.0 1.7 1 1 1 2 2 2 1 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like bcl-2I13 PF12201.8 KFQ97408.1 - 0.025 14.5 1.2 0.34 10.8 0.7 2.1 2 0 0 2 2 2 0 Bcl2-interacting killer, BH3-domain containing Polysacc_deac_3 PF15421.6 KFQ97408.1 - 0.16 10.5 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Putative polysaccharide deacetylase DUF4051 PF13260.6 KFQ97408.1 - 2.9 7.7 6.7 1.4 8.7 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) Humanin PF15040.6 KFQ97409.1 - 0.022 14.2 2.2 0.047 13.1 2.2 1.4 1 0 0 1 1 1 0 Humanin family IPK PF03770.16 KFQ97410.1 - 3e-65 219.8 0.0 3.9e-65 219.4 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase MSC PF09402.10 KFQ97411.1 - 6.4e-17 62.0 1.8 1.1e-16 61.3 1.8 1.4 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain PV-1 PF06637.11 KFQ97411.1 - 0.22 10.3 0.0 0.34 9.7 0.0 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) NAGLU_N PF12971.7 KFQ97411.1 - 0.24 11.2 0.5 0.55 10.0 0.0 1.8 2 0 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain TssO PF17561.2 KFQ97411.1 - 0.29 11.2 1.9 0.72 10.0 0.1 2.1 2 0 0 2 2 2 0 Type VI secretion system, TssO 7tm_1 PF00001.21 KFQ97412.1 - 6.8e-47 160.0 12.5 9.7e-47 159.5 12.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Rhodopsin_N PF10413.9 KFQ97412.1 - 1.1e-25 89.2 3.3 2.5e-25 88.0 3.3 1.7 1 0 0 1 1 1 1 Amino terminal of the G-protein receptor rhodopsin 7TM_GPCR_Srw PF10324.9 KFQ97412.1 - 2.3e-13 50.2 14.9 1.6e-12 47.4 14.9 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 KFQ97412.1 - 3.6e-08 33.1 15.4 5.5e-08 32.5 15.4 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 KFQ97412.1 - 1.9e-07 30.8 16.0 2.8e-07 30.2 16.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv TAS2R PF05296.13 KFQ97412.1 - 6.6e-05 22.2 8.6 0.00081 18.6 1.3 2.2 2 0 0 2 2 2 2 Taste receptor protein (TAS2R) 7tm_4 PF13853.6 KFQ97412.1 - 9.8e-05 22.2 12.1 0.00043 20.1 12.1 1.9 1 1 0 1 1 1 1 Olfactory receptor DUF4079 PF13301.6 KFQ97412.1 - 0.0042 17.3 4.4 0.089 12.9 0.6 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4079) FA_desaturase PF00487.24 KFQ97412.1 - 0.9 9.3 12.3 0.12 12.2 0.5 2.3 2 1 0 2 2 2 0 Fatty acid desaturase 60KD_IMP PF02096.20 KFQ97412.1 - 3.4 7.6 8.3 18 5.2 7.8 2.4 1 1 0 1 1 1 0 60Kd inner membrane protein ANF_receptor PF01094.28 KFQ97413.1 - 8.3e-109 363.9 0.0 1e-108 363.6 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 KFQ97413.1 - 3.2e-59 200.6 13.9 4.4e-59 200.1 13.9 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 KFQ97413.1 - 3.3e-13 49.4 11.5 6.7e-13 48.4 11.5 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.6 KFQ97413.1 - 6e-11 42.6 0.0 9.8e-10 38.6 0.0 2.1 2 0 0 2 2 2 1 Periplasmic binding protein Haem_degrading PF03928.14 KFQ97413.1 - 0.013 15.5 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Haem-degrading NUDIX PF00293.28 KFQ97414.1 - 5.8e-16 58.7 0.3 6.7e-16 58.5 0.3 1.1 1 0 0 1 1 1 1 NUDIX domain Ets PF00178.22 KFQ97416.1 - 2.9e-34 117.4 1.3 6.2e-34 116.3 1.0 1.7 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.16 KFQ97416.1 - 9.5e-25 86.4 0.1 1.8e-24 85.5 0.1 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_3 PF18016.1 KFQ97416.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) N_BRCA1_IG PF16158.5 KFQ97417.1 - 3.9e-34 117.4 0.2 7e-34 116.6 0.2 1.4 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene CARDB PF07705.11 KFQ97417.1 - 0.067 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 CARDB zf-U1 PF06220.12 KFQ97418.1 - 1.9e-20 72.3 8.3 2.5e-20 71.9 8.3 1.2 1 0 0 1 1 1 1 U1 zinc finger Phage_int_SAM_3 PF14659.6 KFQ97418.1 - 0.12 12.6 0.1 0.7 10.2 0.1 1.9 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain zf-C2H2_jaz PF12171.8 KFQ97418.1 - 2.1 8.7 9.9 25 5.3 9.9 2.1 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFQ97418.1 - 2.5 8.6 5.1 24 5.5 5.1 2.1 1 1 0 1 1 1 0 Zinc-finger of C2H2 type VPS13 PF16908.5 KFQ97419.1 - 0.0032 17.3 1.0 0.16 11.8 1.0 2.3 1 1 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal TAFII28 PF04719.14 KFQ97421.1 - 1.3e-39 134.1 0.0 2.3e-39 133.3 0.0 1.4 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.23 KFQ97421.1 - 2.5e-06 27.6 0.0 5.5e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-X PF09415.10 KFQ97421.1 - 0.029 14.7 1.6 8.4 6.8 0.4 2.7 3 0 0 3 3 3 0 CENP-S associating Centromere protein X PID PF00640.23 KFQ97422.1 - 1.9e-19 70.1 0.9 4e-19 69.0 0.9 1.5 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFQ97422.1 - 0.00031 20.9 0.0 0.00053 20.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.6 KFQ97422.1 - 0.0035 17.2 0.0 0.0042 17.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Coq4 PF05019.13 KFQ97422.1 - 0.079 12.3 0.0 0.14 11.5 0.0 1.5 2 0 0 2 2 2 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 FXa_inhibition PF14670.6 KFQ97423.1 - 2e-56 188.0 184.5 1.1e-10 41.6 8.5 12.5 12 1 0 12 12 12 9 Coagulation Factor Xa inhibitory site Ephrin_rec_like PF07699.13 KFQ97423.1 - 9.7e-38 127.7 44.9 6.1e-14 51.5 7.5 6.6 5 1 0 5 5 5 3 Putative ephrin-receptor like cEGF PF12662.7 KFQ97423.1 - 1.7e-35 120.6 103.0 2.5e-08 33.7 0.1 12.1 13 1 0 13 13 13 8 Complement Clr-like EGF-like EGF_CA PF07645.15 KFQ97423.1 - 1.5e-27 95.5 96.0 5.6e-09 36.1 10.1 11.8 13 0 0 13 13 13 6 Calcium-binding EGF domain CUB PF00431.20 KFQ97423.1 - 1.6e-18 67.0 0.0 4.4e-18 65.6 0.0 1.8 1 0 0 1 1 1 1 CUB domain EGF_3 PF12947.7 KFQ97423.1 - 2.9e-17 62.6 153.3 3.6e-10 39.9 11.7 12.1 12 1 0 12 12 12 8 EGF domain EGF PF00008.27 KFQ97423.1 - 1.1e-12 48.0 145.4 1.7e-05 25.0 7.2 12.5 12 1 1 13 13 13 8 EGF-like domain hEGF PF12661.7 KFQ97423.1 - 0.001 19.6 1.4 0.001 19.6 1.4 13.3 13 0 0 13 13 13 5 Human growth factor-like EGF Ribosomal_L1 PF00687.21 KFQ97424.1 - 3.5e-45 154.3 4.9 4.3e-45 154.0 4.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family TetR PF13972.6 KFQ97424.1 - 0.067 12.9 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Bacterial transcriptional repressor DUF3671 PF12420.8 KFQ97424.1 - 0.069 13.2 3.0 0.13 12.4 2.9 1.5 1 1 0 1 1 1 0 Protein of unknown function zf-H2C2_2 PF13465.6 KFQ97425.1 - 3.6e-29 99.9 18.5 9.3e-10 38.5 1.7 4.2 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ97425.1 - 1.6e-22 78.7 16.0 1.5e-07 31.4 0.3 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ97425.1 - 2.4e-17 62.1 14.5 0.00014 22.4 0.3 4.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ97425.1 - 4.3e-11 42.8 0.9 0.011 16.0 0.1 4.4 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 KFQ97425.1 - 1e-06 29.0 4.7 0.37 10.9 0.0 3.5 1 1 1 3 3 3 3 Aberrant zinc-finger zf-C2H2_6 PF13912.6 KFQ97425.1 - 0.00022 21.1 8.1 0.25 11.4 0.1 4.1 4 1 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFQ97425.1 - 0.00029 20.5 15.2 0.13 12.0 2.2 4.7 4 1 0 4 4 4 3 C2H2-type zinc-finger domain zf-met PF12874.7 KFQ97425.1 - 0.0003 21.1 5.0 3.4 8.2 0.1 4.0 4 0 0 4 4 4 2 Zinc-finger of C2H2 type Ogr_Delta PF04606.12 KFQ97425.1 - 0.0012 18.7 2.4 5.2 7.1 0.0 3.4 1 1 2 3 3 3 1 Ogr/Delta-like zinc finger zf-C2H2_8 PF15909.5 KFQ97425.1 - 0.0014 18.9 3.7 0.067 13.5 0.4 2.2 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-TRAF PF02176.18 KFQ97425.1 - 0.0077 16.9 1.9 0.0077 16.9 1.9 2.3 1 1 2 3 3 3 1 TRAF-type zinc finger zf-C2H2_11 PF16622.5 KFQ97425.1 - 0.02 14.7 5.7 2.9 7.7 0.2 3.8 4 0 0 4 4 4 0 zinc-finger C2H2-type FOXP-CC PF16159.5 KFQ97425.1 - 0.042 14.5 3.9 20 5.9 0.0 3.5 3 1 1 4 4 4 0 FOXP coiled-coil domain zf-LYAR PF08790.11 KFQ97425.1 - 0.049 13.5 9.5 10 6.1 0.2 4.4 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf_ZIC PF18366.1 KFQ97425.1 - 0.05 13.7 4.7 8.9 6.5 0.1 3.8 2 2 2 4 4 4 0 Zic proteins zinc finger domain zf-DNA_Pol PF08996.10 KFQ97425.1 - 0.057 13.2 2.0 0.34 10.6 2.0 1.9 1 1 0 1 1 1 0 DNA Polymerase alpha zinc finger zf-C2HC_2 PF13913.6 KFQ97425.1 - 0.16 11.9 9.0 4.9 7.2 0.2 4.4 4 1 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 KFQ97425.1 - 0.16 11.8 0.2 23 4.9 0.0 2.7 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) IBR PF01485.21 KFQ97425.1 - 0.18 12.1 8.4 1.2 9.4 1.0 3.1 1 1 3 4 4 4 0 IBR domain, a half RING-finger domain zf-C2H2 PF00096.26 KFQ97426.1 - 3.3e-08 33.5 9.4 0.00042 20.6 1.4 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ97426.1 - 0.00019 22.0 11.9 0.046 14.6 0.9 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KFQ97426.1 - 0.014 16.0 4.3 0.045 14.4 0.5 2.1 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KFQ97426.1 - 0.034 14.2 9.3 0.13 12.3 1.5 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger Zn_Tnp_IS91 PF14319.6 KFQ97426.1 - 0.035 14.1 3.3 0.051 13.6 3.3 1.4 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-C2H2_aberr PF17017.5 KFQ97426.1 - 0.16 12.1 5.5 0.13 12.4 2.5 1.9 1 1 1 2 2 2 0 Aberrant zinc-finger zf-H2C2_2 PF13465.6 KFQ97426.1 - 0.18 12.3 16.8 1.2 9.6 6.4 3.0 3 0 0 3 3 3 0 Zinc-finger double domain FYDLN_acid PF09538.10 KFQ97426.1 - 0.29 11.8 1.9 0.83 10.4 1.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CpXC PF14353.6 KFQ97426.1 - 0.32 11.1 2.8 0.31 11.1 1.9 1.6 1 1 0 1 1 1 0 CpXC protein PH PF00169.29 KFQ97427.1 - 1.6e-18 67.1 2.4 2.3e-18 66.7 0.7 2.1 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KFQ97427.1 - 1.5e-05 25.4 6.4 1.5e-05 25.4 6.4 3.4 3 1 0 3 3 3 1 Pleckstrin homology domain PH_3 PF14593.6 KFQ97427.1 - 7.8e-05 22.7 2.8 9.1e-05 22.5 0.1 2.5 2 0 0 2 2 2 1 PH domain PH_2 PF08458.10 KFQ97427.1 - 0.0041 17.4 2.0 0.013 15.8 0.0 2.7 2 0 0 2 2 2 1 Plant pleckstrin homology-like region EF-hand_6 PF13405.6 KFQ97427.1 - 0.025 14.5 0.0 0.099 12.6 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain zf-C4 PF00105.18 KFQ97428.1 - 4.9e-09 36.5 5.0 7.5e-09 35.9 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Zn_Tnp_IS91 PF14319.6 KFQ97428.1 - 0.1 12.6 1.3 0.14 12.3 1.3 1.3 1 0 0 1 1 1 0 Transposase zinc-binding domain FA_FANCE PF11510.8 KFQ97429.1 - 2.1e-66 224.0 15.3 4.1e-66 223.0 15.3 1.5 1 0 0 1 1 1 1 Fanconi Anaemia group E protein FANCE MRVI1 PF05781.12 KFQ97430.1 - 2.8e-55 188.0 3.7 3.5e-55 187.7 3.7 1.0 1 0 0 1 1 1 1 MRVI1 protein She9_MDM33 PF05546.11 KFQ97430.1 - 0.053 13.3 2.6 0.074 12.9 2.6 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family Not3 PF04065.15 KFQ97430.1 - 0.61 9.5 6.3 0.84 9.0 5.7 1.3 1 1 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component AAA_33 PF13671.6 KFQ97430.1 - 1.5 9.0 5.9 0.38 10.9 0.5 2.1 2 0 0 2 2 2 0 AAA domain Exo_endo_phos PF03372.23 KFQ97432.1 - 1.5e-17 63.9 0.0 2.3e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Phage_holin_3_6 PF07332.11 KFQ97432.1 - 1.2 9.2 11.5 2.2 8.4 11.5 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III YBD PF17725.1 KFQ97433.1 - 5.1e-96 320.5 0.5 6.6e-96 320.1 0.5 1.1 1 0 0 1 1 1 1 YAP binding domain TEA PF01285.18 KFQ97433.1 - 4e-27 94.1 0.0 8.3e-27 93.1 0.0 1.5 1 0 0 1 1 1 1 TEA/ATTS domain Rotamase_2 PF13145.6 KFQ97433.1 - 0.13 13.1 0.0 0.24 12.2 0.0 1.4 1 0 0 1 1 1 0 PPIC-type PPIASE domain Tub PF01167.18 KFQ97434.1 - 1.1e-95 320.0 0.0 1.2e-95 319.8 0.0 1.0 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.8 KFQ97434.1 - 0.039 13.5 0.0 0.25 10.9 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3527) FKBP_C PF00254.28 KFQ97435.1 - 2.6e-46 155.9 0.1 2.8e-28 98.1 0.0 2.3 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 KFQ97435.1 - 1.9e-15 55.9 13.6 1.5e-08 34.1 1.9 4.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ97435.1 - 4.1e-11 42.2 5.8 2.6e-05 24.1 0.7 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ97435.1 - 7.9e-11 41.2 10.2 2.8e-05 23.9 1.1 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ97435.1 - 3.6e-07 30.4 1.1 0.00056 20.1 1.0 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ97435.1 - 3.3e-06 27.5 0.8 0.0014 19.1 0.7 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ97435.1 - 4.8e-06 26.2 0.7 3e-05 23.7 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFQ97435.1 - 8.2e-06 26.1 2.6 0.044 14.4 0.4 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ97435.1 - 9.1e-05 22.1 2.4 0.046 13.4 0.1 3.3 2 1 1 3 3 3 2 TPR repeat Fis1_TPR_C PF14853.6 KFQ97435.1 - 0.0001 22.3 2.2 0.012 15.7 0.2 2.5 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 KFQ97435.1 - 0.00024 21.2 0.1 0.0013 18.9 0.1 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat FKBP_N_2 PF18023.1 KFQ97435.1 - 0.0028 17.8 0.0 0.034 14.2 0.0 2.8 3 1 0 3 3 3 1 BDBT FKBP like N-terminal DUF3856 PF12968.7 KFQ97435.1 - 0.0061 16.6 0.3 0.011 15.8 0.3 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_16 PF13432.6 KFQ97435.1 - 0.014 16.1 0.1 0.16 12.7 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PknG_TPR PF16918.5 KFQ97435.1 - 0.027 13.2 0.1 0.042 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat ANAPC3 PF12895.7 KFQ97435.1 - 0.14 12.4 6.7 0.31 11.3 1.8 2.8 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KFQ97435.1 - 0.57 10.7 3.3 45 4.8 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Colipase_C PF02740.14 KFQ97436.1 - 3.7e-25 87.8 2.3 7.1e-25 86.9 2.3 1.5 1 0 0 1 1 1 1 Colipase, C-terminal domain Colipase PF01114.18 KFQ97436.1 - 2.6e-20 71.8 3.4 4.8e-20 70.9 3.4 1.5 1 0 0 1 1 1 1 Colipase, N-terminal domain Colipase-like PF15083.6 KFQ97436.1 - 0.0016 18.5 3.2 0.002 18.2 3.2 1.1 1 0 0 1 1 1 1 Colipase-like Prokineticin PF06607.11 KFQ97436.1 - 0.66 10.3 7.6 1.3 9.4 7.6 1.6 1 1 0 1 1 1 0 Prokineticin OapA_N PF08525.11 KFQ97436.1 - 5.2 7.1 6.1 2.2 8.3 0.1 2.1 1 1 1 2 2 2 0 Opacity-associated protein A N-terminal motif L_HMGIC_fpl PF10242.9 KFQ97437.1 - 7.8e-61 205.4 7.4 8.7e-61 205.3 7.4 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.20 KFQ97437.1 - 0.00025 21.0 6.9 0.00029 20.7 6.6 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFQ97437.1 - 1.1 8.9 10.0 2.3 7.9 9.5 1.7 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Pkinase PF00069.25 KFQ97438.1 - 6.8e-44 150.2 0.0 1.1e-22 80.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ97438.1 - 1.7e-14 53.8 0.0 2.3e-10 40.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFQ97438.1 - 0.0019 17.0 0.0 0.0024 16.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Sulfate_transp PF00916.20 KFQ97439.1 - 3.5e-74 249.8 23.1 3.5e-74 249.8 23.1 1.6 2 0 0 2 2 2 1 Sulfate permease family STAS PF01740.21 KFQ97439.1 - 2.1e-21 75.7 0.0 1.2e-20 73.2 0.0 2.1 1 1 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KFQ97439.1 - 8.8e-06 26.1 13.3 2.7e-05 24.5 3.5 3.7 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily PRIMA1 PF16101.5 KFQ97439.1 - 0.035 14.2 0.2 0.12 12.4 0.2 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Ribosomal_S27e PF01667.17 KFQ97439.1 - 3.7 7.3 5.5 0.43 10.3 0.8 1.9 2 1 0 2 2 2 0 Ribosomal protein S27 Pkinase PF00069.25 KFQ97440.1 - 3.9e-59 200.2 0.1 4.6e-59 199.9 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ97440.1 - 7e-28 97.6 0.0 9.4e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFQ97440.1 - 6.6e-05 22.4 0.4 0.0001 21.7 0.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFQ97440.1 - 0.0067 16.4 0.4 0.031 14.2 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFQ97440.1 - 0.039 12.9 0.4 0.059 12.3 0.4 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KFQ97440.1 - 0.059 12.7 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Lectin_C PF00059.21 KFQ97442.1 - 3e-14 53.7 3.2 3e-14 53.7 3.2 1.8 2 0 0 2 2 2 1 Lectin C-type domain Ly49 PF08391.10 KFQ97442.1 - 0.13 12.6 0.0 0.13 12.6 0.0 2.0 2 1 0 2 2 2 0 Ly49-like protein, N-terminal region TMEM52 PF14979.6 KFQ97443.1 - 2.2e-61 206.1 0.1 2.7e-61 205.9 0.1 1.0 1 0 0 1 1 1 1 Transmembrane 52 Herpes_LMP2 PF07415.11 KFQ97443.1 - 0.094 11.5 0.5 0.14 10.9 0.3 1.4 2 0 0 2 2 2 0 Gammaherpesvirus latent membrane protein (LMP2) protein UL42 PF17638.2 KFQ97443.1 - 0.17 11.8 0.9 0.94 9.5 0.3 2.1 2 0 0 2 2 2 0 HCMV UL42 Atg8 PF02991.16 KFQ97444.1 - 2.8e-49 165.6 0.2 3.2e-49 165.4 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KFQ97444.1 - 4.1e-08 33.5 0.0 5.1e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 VitD-bind_III PF09164.10 KFQ97444.1 - 0.16 12.0 0.4 0.26 11.3 0.4 1.3 1 0 0 1 1 1 0 Vitamin D binding protein, domain III Pkinase_Tyr PF07714.17 KFQ97445.1 - 1.1e-64 218.3 0.0 1.5e-64 217.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ97445.1 - 2.7e-32 112.2 0.0 4.1e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KFQ97445.1 - 1.7e-05 24.3 0.0 3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like MAP17 PF15807.5 KFQ97445.1 - 0.0016 18.6 0.5 0.006 16.8 0.0 1.9 2 0 0 2 2 2 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Kdo PF06293.14 KFQ97445.1 - 0.048 13.0 0.1 0.086 12.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YMF19 PF02326.15 KFQ97445.1 - 0.066 14.0 0.1 0.16 12.8 0.1 1.6 1 0 0 1 1 1 0 Plant ATP synthase F0 TMEM154 PF15102.6 KFQ97445.1 - 0.077 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Cadherin PF00028.17 KFQ97449.1 - 7.1e-85 279.6 1.5 8.5e-18 64.6 0.0 5.2 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFQ97449.1 - 4.6e-18 66.0 0.2 1.2e-17 64.6 0.2 1.7 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_4 PF17803.1 KFQ97449.1 - 2.4e-08 34.5 11.3 0.0011 19.5 0.1 4.2 4 0 0 4 4 4 2 Bacterial cadherin-like domain Cadherin_2 PF08266.12 KFQ97449.1 - 6.5e-06 25.9 0.0 0.65 9.9 0.0 3.9 4 0 0 4 4 4 2 Cadherin-like Cadherin_3 PF16184.5 KFQ97449.1 - 0.00016 21.6 7.4 2.1 8.4 0.1 5.4 6 0 0 6 6 6 1 Cadherin-like Big_9 PF17963.1 KFQ97449.1 - 0.0041 17.8 9.2 1.1 10.0 0.9 4.0 3 0 0 3 3 3 2 Bacterial Ig domain Cadherin_pro PF08758.11 KFQ97449.1 - 0.037 14.2 0.0 3.6 7.8 0.0 2.8 2 0 0 2 2 2 0 Cadherin prodomain like Invasin_D3 PF09134.10 KFQ97449.1 - 0.11 12.8 0.8 3.9 7.8 0.0 3.5 3 1 0 3 3 3 0 Invasin, domain 3 DUF5527 PF17665.1 KFQ97449.1 - 0.54 9.8 2.2 1 8.9 2.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Cadherin PF00028.17 KFQ97453.1 - 1.3e-82 272.3 4.2 5e-19 68.5 0.0 5.4 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFQ97453.1 - 1.9e-57 193.7 0.1 3.5e-57 192.8 0.1 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_3 PF16184.5 KFQ97453.1 - 2.7e-07 30.6 4.1 1.2 9.1 0.0 5.7 6 0 0 6 6 6 2 Cadherin-like Cadherin_2 PF08266.12 KFQ97453.1 - 7.9e-05 22.4 0.0 0.13 12.1 0.0 3.6 3 0 0 3 3 3 1 Cadherin-like Cadherin_pro PF08758.11 KFQ97453.1 - 0.002 18.3 0.0 1.2 9.4 0.0 3.5 3 0 0 3 3 3 1 Cadherin prodomain like ASFV_J13L PF05568.11 KFQ97453.1 - 0.02 14.7 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Invasin_D3 PF09134.10 KFQ97453.1 - 0.046 14.0 2.8 15 6.0 0.0 4.6 4 1 1 5 5 5 0 Invasin, domain 3 DUF4286 PF14114.6 KFQ97453.1 - 0.12 12.9 0.0 0.43 11.1 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) Cadherin_4 PF17803.1 KFQ97453.1 - 1.1 9.9 14.2 4.4 8.0 0.2 4.5 5 0 0 5 5 5 0 Bacterial cadherin-like domain Big_9 PF17963.1 KFQ97453.1 - 1.3 9.8 8.8 21 5.9 0.1 4.4 5 0 0 5 5 5 0 Bacterial Ig domain Cadherin PF00028.17 KFQ97455.1 - 7.3e-70 231.5 8.2 4e-19 68.8 0.4 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFQ97455.1 - 5.1e-44 150.1 0.6 9.8e-44 149.2 0.6 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_pro PF08758.11 KFQ97455.1 - 0.0029 17.7 0.2 2 8.6 0.0 3.2 3 0 0 3 3 3 2 Cadherin prodomain like Cadherin_2 PF08266.12 KFQ97455.1 - 0.11 12.4 0.1 2.5 8.0 0.0 3.1 4 0 0 4 4 4 0 Cadherin-like Herpes_UL56 PF04534.12 KFQ97456.1 - 0.00081 18.9 0.2 0.00081 18.9 0.2 1.6 2 0 0 2 2 2 1 Herpesvirus UL56 protein CYYR1 PF10873.8 KFQ97456.1 - 0.46 10.9 4.2 1.6 9.2 1.0 2.2 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 DUF3915 PF13054.6 KFQ97457.1 - 0.036 14.0 4.6 0.37 10.8 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3915) dNK PF01712.19 KFQ97458.1 - 1.6e-25 90.2 1.2 1.9e-25 89.9 1.2 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 KFQ97458.1 - 0.00051 20.6 0.0 0.0007 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFQ97458.1 - 0.00052 20.2 0.0 0.00079 19.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KFQ97458.1 - 0.00085 19.0 0.1 0.0012 18.6 0.1 1.3 1 1 0 1 1 1 1 Thymidylate kinase AAA_17 PF13207.6 KFQ97458.1 - 0.012 16.1 0.1 0.021 15.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain MARVEL PF01284.23 KFQ97459.1 - 0.0002 21.4 16.5 0.001 19.1 16.4 2.2 1 1 0 1 1 1 1 Membrane-associating domain OAD_gamma PF04277.13 KFQ97459.1 - 0.1 13.2 0.0 0.1 13.2 0.0 2.4 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain MSP1a PF11670.8 KFQ97459.1 - 0.57 9.4 5.4 0.97 8.7 5.4 1.3 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) DUF3792 PF12670.7 KFQ97459.1 - 1.2 9.3 13.1 1.1 9.5 11.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3792) MARVEL PF01284.23 KFQ97460.1 - 1.3e-08 35.0 16.7 2.3e-08 34.2 16.7 1.4 1 1 0 1 1 1 1 Membrane-associating domain Cad PF03596.13 KFQ97460.1 - 0.033 14.1 0.9 0.049 13.5 0.9 1.3 1 0 0 1 1 1 0 Cadmium resistance transporter MARVEL PF01284.23 KFQ97461.1 - 5.4e-14 52.4 14.8 7.9e-14 51.9 14.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain YfhO PF09586.10 KFQ97461.1 - 0.00073 17.9 0.6 0.00083 17.7 0.6 1.0 1 0 0 1 1 1 1 Bacterial membrane protein YfhO DUF373 PF04123.13 KFQ97461.1 - 0.42 10.0 3.6 1.3 8.4 3.9 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF373) YIF1 PF03878.15 KFQ97461.1 - 0.53 9.8 5.1 0.85 9.1 4.9 1.3 1 1 0 1 1 1 0 YIF1 DLIC PF05783.11 KFQ97462.1 - 1.1e-253 842.2 0.0 1.2e-253 842.0 0.0 1.0 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) ABC_tran PF00005.27 KFQ97462.1 - 0.0019 18.7 0.0 0.0036 17.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Roc PF08477.13 KFQ97462.1 - 0.0091 16.2 0.2 0.043 14.0 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 KFQ97462.1 - 0.022 14.7 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 KFQ97462.1 - 0.027 14.2 0.2 0.063 13.0 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KFQ97462.1 - 0.035 14.5 0.1 0.073 13.5 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Arf PF00025.21 KFQ97462.1 - 0.035 13.6 0.2 0.46 9.9 0.0 2.5 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA_22 PF13401.6 KFQ97462.1 - 0.037 14.3 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFQ97462.1 - 0.037 13.9 0.3 8.8 6.2 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 KFQ97462.1 - 0.045 13.5 0.1 0.17 11.7 0.1 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 KFQ97462.1 - 0.046 13.3 0.3 9.3 5.7 0.1 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 KFQ97462.1 - 0.048 13.4 0.1 0.085 12.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain Kinesin PF00225.23 KFQ97462.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain ATPase PF06745.13 KFQ97462.1 - 0.13 11.6 0.2 0.24 10.7 0.2 1.5 1 1 0 1 1 1 0 KaiC AAA_23 PF13476.6 KFQ97462.1 - 0.15 12.5 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KFQ97462.1 - 0.16 11.1 0.0 0.31 10.2 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit SRP54 PF00448.22 KFQ97462.1 - 0.26 10.9 1.0 0.74 9.4 0.4 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Atx10homo_assoc PF09759.9 KFQ97464.1 - 0.00013 21.9 6.8 0.0041 17.1 0.4 3.9 3 2 1 4 4 4 2 Spinocerebellar ataxia type 10 protein domain Drf_GBD PF06371.13 KFQ97464.1 - 0.003 17.2 1.4 0.015 14.9 0.4 2.3 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain ThiF PF00899.21 KFQ97465.1 - 6.6e-21 74.8 0.0 1.9e-20 73.2 0.0 1.8 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 KFQ97465.1 - 1.9e-05 24.8 0.0 0.023 14.9 0.0 3.4 3 0 0 3 3 3 2 Ubiquitin-activating enzyme E1 four-helix bundle Transket_pyr PF02779.24 KFQ97465.1 - 0.048 13.3 0.5 0.1 12.2 0.5 1.5 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain Carb_anhydrase PF00194.21 KFQ97466.1 - 1.3e-97 326.3 0.0 1.5e-97 326.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase PP2C PF00481.21 KFQ97467.1 - 5.3e-41 141.0 0.0 6.1e-38 130.9 0.0 2.2 1 1 1 2 2 2 2 Protein phosphatase 2C Importin_rep PF18773.1 KFQ97467.1 - 1.3 8.8 3.4 13 5.6 0.5 2.5 2 0 0 2 2 2 0 Importin 13 repeat Ras PF00071.22 KFQ97468.1 - 8.5e-27 93.7 0.2 4.7e-26 91.3 0.2 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFQ97468.1 - 2.2e-07 31.1 0.0 7.4e-07 29.4 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KFQ97468.1 - 0.0013 18.6 0.1 0.87 9.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KFQ97468.1 - 0.0026 17.3 0.0 0.046 13.2 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_22 PF13401.6 KFQ97468.1 - 0.011 16.0 0.6 2.7 8.3 0.1 3.0 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 KFQ97468.1 - 0.047 14.2 0.6 0.17 12.4 0.6 2.0 1 1 0 1 1 1 0 ABC transporter AAA PF00004.29 KFQ97468.1 - 0.05 14.0 0.2 0.46 10.9 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFQ97468.1 - 0.052 13.9 0.1 0.4 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 KFQ97468.1 - 0.073 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 KFQ97468.1 - 0.083 12.2 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF2608 PF11019.8 KFQ97468.1 - 0.15 11.5 0.0 0.43 10.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) AAA_5 PF07728.14 KFQ97468.1 - 0.15 12.0 0.2 0.37 10.8 0.2 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) HA1 PF18239.1 KFQ97468.1 - 0.16 11.8 0.0 0.5 10.3 0.0 1.8 2 0 0 2 2 2 0 Hemagglutinin I FeS_assembly_P PF01883.19 KFQ97469.1 - 1.2e-14 54.3 0.1 2.7e-14 53.1 0.0 1.6 1 1 1 2 2 2 1 Iron-sulfur cluster assembly protein COesterase PF00135.28 KFQ97470.1 - 7.3e-142 473.8 0.0 3.8e-105 352.7 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KFQ97470.1 - 4.6e-09 36.4 0.3 1.5e-08 34.7 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KFQ97471.1 - 1.1e-167 559.1 0.0 1.2e-167 558.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFQ97471.1 - 1.9e-09 37.7 2.9 9.3e-09 35.4 2.5 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFQ97471.1 - 0.0018 17.8 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KFQ97471.1 - 0.037 13.7 0.9 0.1 12.2 0.9 1.6 1 1 0 1 1 1 0 Putative esterase Abhydrolase_6 PF12697.7 KFQ97471.1 - 0.11 13.0 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family PDCD2_C PF04194.13 KFQ97472.1 - 7.2e-49 166.2 0.1 9.7e-49 165.8 0.1 1.2 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain ThiF PF00899.21 KFQ97473.1 - 6.4e-57 192.7 0.0 9.8e-57 192.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family UBA2_C PF16195.5 KFQ97473.1 - 1.7e-25 89.5 11.2 1.7e-25 89.5 11.2 2.2 2 0 0 2 2 2 1 SUMO-activating enzyme subunit 2 C-terminus UAE_UbL PF14732.6 KFQ97473.1 - 4e-23 81.8 1.1 1.1e-22 80.4 1.1 1.8 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 KFQ97473.1 - 6.6e-07 29.5 6.3 0.0026 17.7 0.4 2.6 2 1 0 3 3 3 2 Ubiquitin-activating enzyme active site LIM PF00412.22 KFQ97474.1 - 5e-36 122.7 36.5 4e-14 52.6 8.4 3.1 3 0 0 3 3 3 3 LIM domain Mut7-C PF01927.16 KFQ97474.1 - 9 6.4 20.1 0.072 13.2 2.0 3.2 1 1 3 4 4 4 0 Mut7-C RNAse domain PGI PF00342.19 KFQ97475.1 - 1.1e-261 868.6 0.0 1.2e-261 868.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF4473 PF14747.6 KFQ97475.1 - 0.012 16.1 0.1 0.045 14.3 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) DUF4745 PF15923.5 KFQ97477.1 - 2.4e-48 163.5 1.6 6.2e-48 162.2 1.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4745) Rapsyn_N PF10579.9 KFQ97477.1 - 5.7 7.1 0.0 5.7 7.1 0.0 3.2 4 0 0 4 4 4 0 Rapsyn N-terminal myristoylation and linker region LSM14 PF12701.7 KFQ97478.1 - 1.6e-33 114.6 0.0 2.7e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KFQ97478.1 - 5e-31 107.7 7.8 5e-31 107.7 7.8 2.1 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.6 KFQ97478.1 - 5.5e-08 32.8 0.0 1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain GRP PF07172.11 KFQ97478.1 - 2.3 9.0 20.4 13 6.5 13.6 2.7 2 0 0 2 2 2 0 Glycine rich protein family TAF4 PF05236.14 KFQ97479.1 - 2.1e-77 260.6 7.1 2.4e-77 260.4 7.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TAF PF02969.17 KFQ97479.1 - 8e-05 22.7 0.9 0.33 11.2 0.1 2.6 2 0 0 2 2 2 2 TATA box binding protein associated factor (TAF) Presenilin PF01080.17 KFQ97479.1 - 0.029 13.2 1.5 0.037 12.8 1.5 1.1 1 0 0 1 1 1 0 Presenilin DUF1955 PF09205.10 KFQ97479.1 - 0.13 12.0 0.3 0.19 11.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) BTB_2 PF02214.22 KFQ97480.1 - 9.5e-17 61.1 0.1 1.5e-16 60.5 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain Sulfotransfer_2 PF03567.14 KFQ97481.1 - 1.2e-56 192.4 3.9 1.5e-56 192.2 3.9 1.1 1 0 0 1 1 1 1 Sulfotransferase family Peptidase_M24 PF00557.24 KFQ97482.1 - 1.5e-61 207.8 0.1 1.1e-58 198.4 0.1 3.0 3 0 0 3 3 3 1 Metallopeptidase family M24 AMP_N PF05195.16 KFQ97482.1 - 6.1e-28 97.0 0.0 1.4e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.7 KFQ97482.1 - 0.081 13.0 0.6 2.2 8.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3793) bZIP_2 PF07716.15 KFQ97483.1 - 1.4e-15 57.1 16.9 1.9e-15 56.7 16.9 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KFQ97483.1 - 2e-05 24.6 12.4 3.6e-05 23.8 12.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor DUF1319 PF07028.11 KFQ97483.1 - 0.016 15.4 1.6 0.023 14.9 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) Jnk-SapK_ap_N PF09744.9 KFQ97483.1 - 0.035 14.3 6.4 0.048 13.9 6.4 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 bZIP_Maf PF03131.17 KFQ97483.1 - 0.044 14.3 7.7 0.077 13.5 7.7 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Seryl_tRNA_N PF02403.22 KFQ97483.1 - 0.048 13.9 6.9 0.079 13.2 6.9 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 KFQ97483.1 - 0.12 12.9 6.9 0.18 12.3 6.9 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region XhlA PF10779.9 KFQ97483.1 - 0.19 11.9 6.4 0.19 12.0 5.2 1.6 1 1 0 1 1 1 0 Haemolysin XhlA DUF4094 PF13334.6 KFQ97483.1 - 0.34 11.3 3.2 0.52 10.8 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DivIC PF04977.15 KFQ97483.1 - 0.38 10.6 7.7 0.38 10.5 6.5 1.6 1 1 0 1 1 1 0 Septum formation initiator Tho2 PF11262.8 KFQ97483.1 - 0.93 8.6 6.0 1.1 8.3 6.0 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 LAM_C PF12544.8 KFQ97483.1 - 1.8 8.8 6.6 11 6.1 6.6 2.2 1 1 0 1 1 1 0 Lysine-2,3-aminomutase bZIP_2 PF07716.15 KFQ97484.1 - 2.4e-13 49.9 10.3 4.6e-13 49.0 10.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper AA_permease_2 PF13520.6 KFQ97485.1 - 2.8e-58 197.7 43.3 3.5e-58 197.4 43.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFQ97485.1 - 7.7e-32 110.5 37.8 9.8e-32 110.2 37.8 1.1 1 0 0 1 1 1 1 Amino acid permease p53-inducible11 PF14936.6 KFQ97485.1 - 0.26 11.3 10.4 2.5 8.1 2.1 2.6 2 0 0 2 2 2 0 Tumour protein p53-inducible protein 11 DUF5408 PF17402.2 KFQ97485.1 - 0.48 10.3 3.7 1.5 8.8 3.7 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5408) DUF1604 PF07713.13 KFQ97486.1 - 5.1e-35 119.2 0.5 5.1e-35 119.2 0.5 4.5 6 0 0 6 6 6 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KFQ97486.1 - 4.7e-07 29.6 1.2 1.1e-06 28.5 0.1 2.2 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KFQ97486.1 - 0.0024 17.9 0.0 0.0024 17.9 0.0 3.4 3 0 0 3 3 3 1 G-patch domain BRO1 PF03097.18 KFQ97487.1 - 2.6e-95 319.5 0.2 3.1e-95 319.2 0.2 1.1 1 0 0 1 1 1 1 BRO1-like domain HR1 PF02185.16 KFQ97487.1 - 3.2e-13 49.6 7.3 3.5e-13 49.4 4.6 2.5 2 0 0 2 2 2 1 Hr1 repeat PDZ_6 PF17820.1 KFQ97487.1 - 1.2e-05 25.0 0.0 3.2e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFQ97487.1 - 0.0001 22.6 0.0 0.00034 20.9 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PND PF17949.1 KFQ97488.1 - 3.9e-51 172.5 0.2 6.9e-51 171.7 0.2 1.4 1 0 0 1 1 1 1 FANCM pseudonuclease domain HHH_2 PF12826.7 KFQ97488.1 - 1.7e-08 34.4 0.0 3.6e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KFQ97488.1 - 2.6e-06 27.9 0.0 4.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain Rad10 PF03834.14 KFQ97488.1 - 0.00099 19.1 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) 5_3_exonuc PF01367.20 KFQ97488.1 - 0.018 15.6 0.0 0.042 14.4 0.0 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold HHH PF00633.23 KFQ97488.1 - 0.023 14.6 0.2 4.9 7.2 0.0 3.1 3 1 0 3 3 3 0 Helix-hairpin-helix motif Pdase_M17_N2 PF18295.1 KFQ97489.1 - 0.033 14.4 0.6 0.14 12.5 0.6 2.1 1 0 0 1 1 1 0 M17 aminopeptidase N-terminal domain 2 zf-RING_2 PF13639.6 KFQ97490.1 - 1.5e-05 25.2 11.7 1.5e-05 25.2 11.7 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KFQ97490.1 - 5.8e-05 23.0 12.1 5.8e-05 23.0 12.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFQ97490.1 - 6.6e-05 22.9 7.5 8.3e-05 22.5 5.4 2.4 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFQ97490.1 - 0.0024 17.7 11.8 0.0024 17.7 11.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) VIT1 PF01988.19 KFQ97490.1 - 0.069 13.0 0.0 0.075 12.9 0.0 1.2 1 0 0 1 1 1 0 VIT family AA_permease_2 PF13520.6 KFQ97491.1 - 5.1e-62 210.1 45.8 6.9e-62 209.6 45.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFQ97491.1 - 4.9e-25 88.1 43.5 6.7e-25 87.6 43.5 1.2 1 0 0 1 1 1 1 Amino acid permease DUF3098 PF11297.8 KFQ97491.1 - 3.4 7.3 12.0 4.1 7.1 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3098) TUDOR PF00567.24 KFQ97492.1 - 3.1e-08 33.7 0.1 7.4e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 Tudor domain Helicase_C PF00271.31 KFQ97492.1 - 2.4e-07 31.0 0.1 2.2e-06 28.0 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFQ97492.1 - 5.9e-07 29.4 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3885 PF13021.6 KFQ97492.1 - 0.12 12.5 0.0 6 7.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) TUDOR PF00567.24 KFQ97493.1 - 3.6e-12 46.4 2.0 4.4e-12 46.1 2.0 1.1 1 0 0 1 1 1 1 Tudor domain Syntaxin_2 PF14523.6 KFQ97495.1 - 0.0015 18.8 0.4 0.0027 18.1 0.2 1.5 2 0 0 2 2 2 1 Syntaxin-like protein Tic110 PF16940.5 KFQ97495.1 - 0.005 15.4 0.2 0.0064 15.0 0.2 1.1 1 0 0 1 1 1 1 Chloroplast envelope transporter LapD_MoxY_N PF16448.5 KFQ97495.1 - 0.021 14.7 0.3 0.045 13.6 0.0 1.6 2 0 0 2 2 2 0 LapD/MoxY periplasmic domain DUF2155 PF09923.9 KFQ97495.1 - 0.027 14.7 0.3 2.5 8.4 0.1 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2155) DUF1539 PF07560.11 KFQ97495.1 - 0.043 13.9 0.1 0.09 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) dsDNA_bind PF01984.20 KFQ97496.1 - 2.4e-30 105.1 3.4 2.7e-30 104.9 3.4 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Methyltransf_4 PF02390.17 KFQ97496.1 - 0.045 13.2 0.3 0.1 12.1 0.1 1.6 1 1 0 1 1 1 0 Putative methyltransferase Rossmann-like PF10727.9 KFQ97496.1 - 0.11 12.3 0.1 0.14 12.0 0.1 1.1 1 0 0 1 1 1 0 Rossmann-like domain Cadherin PF00028.17 KFQ97497.1 - 3.6e-216 700.4 15.3 6e-20 71.5 0.0 15.6 15 0 0 15 15 15 15 Cadherin domain Laminin_G_2 PF02210.24 KFQ97497.1 - 6.2e-35 120.5 0.1 7.5e-17 62.1 0.0 2.7 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 KFQ97497.1 - 1.2e-26 93.4 0.0 1.5e-12 47.9 0.0 2.6 2 0 0 2 2 2 2 Laminin G domain Cadherin_C PF01049.17 KFQ97497.1 - 7.5e-12 45.8 0.4 7.5e-12 45.8 0.4 1.9 2 0 0 2 2 2 1 Cadherin cytoplasmic region Cadherin_3 PF16184.5 KFQ97497.1 - 5e-11 42.6 14.2 0.02 14.9 0.2 9.8 11 0 0 11 11 11 3 Cadherin-like Cadherin_2 PF08266.12 KFQ97497.1 - 2.5e-10 40.0 0.0 0.22 11.4 0.0 8.6 9 0 0 9 9 9 1 Cadherin-like EGF PF00008.27 KFQ97497.1 - 3.5e-10 40.0 62.1 6.2e-07 29.6 6.2 4.9 5 0 0 5 5 4 4 EGF-like domain Cadherin_pro PF08758.11 KFQ97497.1 - 8.1e-10 38.7 0.0 1.7e-05 24.9 0.0 5.9 6 0 0 6 6 6 1 Cadherin prodomain like hEGF PF12661.7 KFQ97497.1 - 5.9e-06 26.7 44.0 0.0011 19.5 3.7 5.4 4 2 0 4 4 4 3 Human growth factor-like EGF EGF_2 PF07974.13 KFQ97497.1 - 0.0023 18.3 5.2 0.0023 18.3 5.2 4.8 4 0 0 4 4 4 2 EGF-like domain Laminin_G_3 PF13385.6 KFQ97497.1 - 0.0045 17.2 0.0 0.064 13.4 0.0 2.9 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Cadherin_4 PF17803.1 KFQ97497.1 - 0.005 17.4 1.3 0.005 17.4 1.3 11.0 13 0 0 13 13 13 3 Bacterial cadherin-like domain cEGF PF12662.7 KFQ97497.1 - 3.4 7.7 26.8 0.55 10.2 0.1 4.8 4 0 0 4 4 4 0 Complement Clr-like EGF-like Laminin_EGF PF00053.24 KFQ97497.1 - 5.9 7.1 49.5 0.43 10.8 3.5 4.5 3 1 1 4 4 3 0 Laminin EGF domain Dpy19 PF10034.9 KFQ97498.1 - 6.5e-244 811.0 29.2 7.5e-244 810.8 29.2 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation DUF4083 PF13314.6 KFQ97498.1 - 5.1 7.1 9.8 2.3 8.2 0.1 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) zf-C2H2 PF00096.26 KFQ97499.1 - 2.8e-14 52.7 73.8 0.011 16.1 3.3 9.6 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ97499.1 - 4.5e-13 48.8 69.2 0.0095 16.7 3.2 9.6 9 0 0 9 9 9 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFQ97499.1 - 5.4e-10 39.2 65.2 0.00027 21.2 2.0 11.0 12 0 0 12 12 12 6 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFQ97499.1 - 0.0039 16.9 75.5 0.03 14.1 2.7 9.5 10 0 0 10 10 10 6 C2H2-type zinc-finger domain DUF5069 PF16798.5 KFQ97499.1 - 0.047 13.9 0.5 7.4 6.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5069) zf_C2H2_ZHX PF18387.1 KFQ97499.1 - 4.2 7.1 41.6 0.25 11.0 2.3 7.9 6 2 2 8 8 8 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 KFQ97500.1 - 2.5e-10 40.6 20.8 0.0063 16.8 1.2 5.3 3 2 1 4 4 4 4 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KFQ97500.1 - 1.8e-09 37.5 27.3 0.034 14.6 2.9 5.7 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ97500.1 - 2.3e-08 34.2 22.0 0.062 14.2 2.6 5.8 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFQ97500.1 - 7.4e-06 25.8 21.5 0.024 14.6 2.4 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 KFQ97500.1 - 0.00045 20.5 7.0 0.026 14.9 2.1 3.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KFQ97500.1 - 0.0027 18.1 11.0 2.5 8.6 0.0 5.1 5 0 0 5 5 5 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 KFQ97500.1 - 0.007 16.6 14.9 0.058 13.7 0.8 4.6 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KFQ97500.1 - 0.037 14.1 10.1 6.4 7.0 0.1 5.0 5 0 0 5 5 5 0 Zinc ribbon domain DUF678 PF05077.12 KFQ97500.1 - 0.065 13.4 3.7 20 5.4 0.0 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF678) zf-C2H2_3rep PF18868.1 KFQ97500.1 - 0.08 13.6 15.0 0.42 11.3 0.8 5.1 4 1 1 5 5 5 0 Zinc finger C2H2-type, 3 repeats PyrI_C PF02748.15 KFQ97500.1 - 0.16 11.9 2.3 4.5 7.2 0.1 3.3 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Homeodomain PF00046.29 KFQ97500.1 - 0.2 11.5 0.4 0.92 9.4 0.2 2.4 2 0 0 2 2 2 0 Homeodomain zf-C2HC_2 PF13913.6 KFQ97500.1 - 0.37 10.7 1.4 0.53 10.3 0.1 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 KFQ97500.1 - 0.91 10.1 12.9 3.1 8.4 0.1 5.2 5 0 0 5 5 4 0 Zinc-finger double domain zf-C2H2_11 PF16622.5 KFQ97500.1 - 1.2 8.9 14.4 0.34 10.7 2.1 3.9 4 0 0 4 4 4 0 zinc-finger C2H2-type OTT_1508_deam PF14441.6 KFQ97500.1 - 1.6 8.8 4.3 3.8 7.6 0.1 3.0 3 0 0 3 3 3 0 OTT_1508-like deaminase zf-CpG_bind_C PF12269.8 KFQ97500.1 - 3.3 7.4 12.0 0.35 10.6 0.4 3.3 5 0 0 5 5 5 0 CpG binding protein zinc finger C terminal domain zf-C2H2_9 PF16293.5 KFQ97500.1 - 5.8 6.8 11.0 4.6 7.2 0.2 4.4 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_assoc PF16606.5 KFQ97501.1 - 3.4e-40 136.1 17.2 3.4e-40 136.1 17.2 2.8 2 0 0 2 2 2 1 Unstructured conserved, between two C2H2-type zinc-fingers zf-C2H2 PF00096.26 KFQ97501.1 - 6.7e-32 108.2 74.1 2.3e-05 24.6 4.0 10.4 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ97501.1 - 1.3e-25 87.8 75.5 0.0022 18.7 2.8 10.8 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFQ97501.1 - 3.4e-20 71.5 82.3 6.7e-08 32.6 2.4 12.5 13 0 0 13 13 12 6 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFQ97501.1 - 9.1e-15 54.1 61.0 2.8e-07 30.1 0.9 10.3 11 0 0 11 11 11 4 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KFQ97501.1 - 9e-08 32.3 48.6 0.0061 16.8 1.7 7.8 6 3 1 7 7 7 5 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 KFQ97501.1 - 0.0004 20.1 10.0 0.7 9.7 0.1 5.9 5 2 2 7 7 7 2 GAGA factor Actin_micro PF17003.5 KFQ97501.1 - 0.0052 16.0 22.0 7.5 5.6 0.2 6.0 4 2 1 5 5 5 2 Putative actin-like family Zn-ribbon_8 PF09723.10 KFQ97501.1 - 0.01 15.9 33.0 0.52 10.5 3.3 6.2 5 2 1 6 6 6 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 KFQ97501.1 - 0.012 16.0 43.1 4.7 7.6 0.1 10.0 5 3 4 9 9 9 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 KFQ97501.1 - 0.019 15.7 2.9 0.019 15.7 2.9 5.5 5 2 3 8 8 8 0 Zinc finger C2H2-type, 3 repeats DUF3268 PF11672.8 KFQ97501.1 - 0.032 14.6 15.2 0.035 14.4 1.2 4.0 4 0 0 4 4 3 0 zinc-finger-containing domain CpXC PF14353.6 KFQ97501.1 - 0.051 13.6 26.4 13 5.9 0.4 7.1 5 3 3 8 8 7 0 CpXC protein TerY_C PF15616.6 KFQ97501.1 - 0.51 10.4 8.0 10 6.2 0.0 3.6 4 0 0 4 4 3 0 TerY-C metal binding domain DZR PF12773.7 KFQ97501.1 - 0.54 10.3 22.5 0.14 12.2 0.4 5.4 5 1 0 5 5 5 0 Double zinc ribbon zf_C2H2_ZHX PF18387.1 KFQ97501.1 - 4 7.2 25.4 0.61 9.8 0.4 5.8 4 2 2 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain Prefoldin PF02996.17 KFQ97502.1 - 2.2e-16 59.8 1.4 4.1e-16 59.0 0.0 2.1 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.6 KFQ97502.1 - 3.8e-09 36.5 0.5 1.5e-08 34.6 0.0 2.3 2 0 0 2 2 2 1 Prefoldin subunit SIN1 PF05422.12 KFQ97502.1 - 0.00093 19.8 0.9 0.00093 19.8 0.9 2.6 3 0 0 3 3 3 1 Stress-activated map kinase interacting protein 1 (SIN1) DUF3835 PF12927.7 KFQ97502.1 - 0.39 11.6 0.2 0.39 11.6 0.2 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF3835) DUF1639 PF07797.14 KFQ97502.1 - 0.79 9.7 3.7 1.3 9.1 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1639) Cyclin_N PF00134.23 KFQ97503.1 - 8.4e-44 148.4 1.5 1.3e-43 147.7 1.5 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFQ97503.1 - 3.7e-19 69.0 0.0 7.4e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain BtpA PF03437.15 KFQ97504.1 - 4.5e-34 118.0 0.1 4.8e-34 117.9 0.1 1.0 1 0 0 1 1 1 1 BtpA family UPF0560 PF10577.9 KFQ97508.1 - 0 1301.3 4.6 0 1301.1 4.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0560 FAM176 PF14851.6 KFQ97508.1 - 0.029 14.0 4.3 7.5 6.2 2.9 2.8 2 0 0 2 2 2 0 FAM176 family Orthoreo_P10 PF07204.11 KFQ97508.1 - 0.11 12.4 0.1 0.26 11.3 0.1 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DUF4131 PF13567.6 KFQ97508.1 - 0.14 11.8 0.1 15 5.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Adeno_E3_CR2 PF02439.15 KFQ97508.1 - 0.25 11.2 1.5 0.44 10.3 1.5 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CsgF PF10614.9 KFQ97508.1 - 2.7 8.2 4.8 6.7 6.9 4.8 1.6 1 0 0 1 1 1 0 Type VIII secretion system (T8SS), CsgF protein Integrin_alpha2 PF08441.12 KFQ97509.1 - 9.2e-114 380.9 0.5 1.1e-113 380.6 0.5 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 KFQ97509.1 - 1.4e-25 89.1 17.0 1.6e-10 40.9 0.0 5.7 6 0 0 6 6 6 4 FG-GAP repeat VCBS PF13517.6 KFQ97509.1 - 6.3e-08 33.1 13.5 0.00026 21.5 0.9 3.9 2 2 3 5 5 5 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF4205 PF13898.6 KFQ97510.1 - 1.4e-53 182.0 0.1 7.2e-50 169.9 0.0 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4205) PTE PF02126.18 KFQ97511.1 - 1e-118 396.2 0.0 1.1e-118 396.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotriesterase family TatD_DNase PF01026.21 KFQ97511.1 - 4.3e-06 26.3 0.0 5.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase C1q PF00386.21 KFQ97512.1 - 2.1e-12 47.4 0.0 2.2e-12 47.3 0.0 1.0 1 0 0 1 1 1 1 C1q domain TNF PF00229.18 KFQ97512.1 - 0.12 12.3 0.0 0.12 12.3 0.0 1.0 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family LRR_8 PF13855.6 KFQ97513.1 - 1.1e-27 95.6 46.9 1.5e-09 37.5 5.3 3.6 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KFQ97513.1 - 3.9e-16 58.9 22.5 6.3e-06 26.4 3.5 4.2 1 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFQ97513.1 - 6.9e-09 35.0 17.5 1.5 9.6 0.2 6.5 6 1 0 6 6 6 5 Leucine Rich Repeat LRR_6 PF13516.6 KFQ97513.1 - 1.1e-05 25.0 18.3 3.8 7.8 0.0 6.3 6 0 0 6 6 6 5 Leucine Rich repeat LRR_9 PF14580.6 KFQ97513.1 - 0.00039 20.0 6.0 0.038 13.5 1.5 2.2 1 1 1 2 2 2 2 Leucine-rich repeat DNA_methylase PF00145.17 KFQ97515.1 - 7.1e-37 127.5 0.0 9.5e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Filament PF00038.21 KFQ97516.1 - 3.6e-114 381.5 51.4 4.3e-114 381.3 51.4 1.1 1 0 0 1 1 1 1 Intermediate filament protein Filament_head PF04732.14 KFQ97516.1 - 1.4e-16 61.2 8.2 2.7e-16 60.2 8.2 1.5 1 0 0 1 1 1 1 Intermediate filament head (DNA binding) region DUF1664 PF07889.12 KFQ97516.1 - 0.00071 19.6 22.4 0.0023 18.0 1.3 3.7 3 1 0 4 4 3 2 Protein of unknown function (DUF1664) DUF4515 PF14988.6 KFQ97516.1 - 0.01 15.7 44.4 0.035 14.0 31.7 3.0 1 1 1 3 3 3 0 Domain of unknown function (DUF4515) TPR_MLP1_2 PF07926.12 KFQ97516.1 - 0.011 15.8 53.6 0.11 12.6 14.3 4.2 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein TolA_bind_tri PF16331.5 KFQ97516.1 - 0.023 14.8 3.2 0.023 14.8 3.2 6.6 2 1 4 6 6 6 0 TolA binding protein trimerisation FPP PF05911.11 KFQ97516.1 - 0.023 12.9 35.0 0.084 11.1 19.1 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Golgin_A5 PF09787.9 KFQ97516.1 - 0.026 14.0 42.8 0.32 10.4 22.6 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 Jnk-SapK_ap_N PF09744.9 KFQ97516.1 - 0.051 13.8 45.8 0.43 10.8 18.3 3.9 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Atg14 PF10186.9 KFQ97516.1 - 0.13 11.3 27.0 1.8 7.6 11.3 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 bZIP_1 PF00170.21 KFQ97516.1 - 0.16 12.1 28.9 4 7.6 1.4 5.9 4 1 1 5 5 5 0 bZIP transcription factor Laminin_II PF06009.12 KFQ97516.1 - 0.17 11.9 27.6 3.4 7.7 1.3 3.6 1 1 3 4 4 4 0 Laminin Domain II Trimer_CC PF08954.11 KFQ97516.1 - 0.21 11.2 8.2 12 5.6 1.3 3.9 3 0 0 3 3 3 0 Trimerisation motif DUF5082 PF16888.5 KFQ97516.1 - 0.25 11.6 27.2 0.14 12.4 9.8 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF5082) Baculo_PEP_C PF04513.12 KFQ97516.1 - 0.29 11.2 19.0 0.74 9.9 2.2 4.4 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.8 KFQ97516.1 - 0.42 8.1 40.9 1.7 6.1 41.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF573 PF04504.14 KFQ97516.1 - 0.5 11.0 10.9 1.5 9.5 0.7 3.6 2 2 1 3 3 3 0 Protein of unknown function, DUF573 HOOK PF05622.12 KFQ97516.1 - 0.55 8.3 44.8 1.1 7.3 42.6 2.0 1 1 1 2 2 2 0 HOOK protein HALZ PF02183.18 KFQ97516.1 - 0.64 10.3 33.8 0.15 12.3 2.1 6.6 7 1 0 7 7 5 0 Homeobox associated leucine zipper HMMR_N PF15905.5 KFQ97516.1 - 0.74 9.2 40.0 0.014 14.9 10.4 2.8 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal GAS PF13851.6 KFQ97516.1 - 0.81 9.0 49.0 0.062 12.6 14.8 3.9 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF4200 PF13863.6 KFQ97516.1 - 0.93 9.9 47.3 0.022 15.2 16.8 4.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) EzrA PF06160.12 KFQ97516.1 - 1.1 7.4 40.5 0.021 13.0 9.1 3.1 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA DUF1759 PF03564.15 KFQ97516.1 - 1.3 8.9 15.7 1.1 9.2 0.6 3.6 1 1 1 3 3 3 0 Protein of unknown function (DUF1759) Rab5-bind PF09311.11 KFQ97516.1 - 2 7.7 44.3 0.47 9.8 12.4 3.3 1 1 0 2 2 2 0 Rabaptin-like protein EspB PF05802.11 KFQ97516.1 - 2.5 8.0 15.4 0.13 12.3 7.0 2.7 1 1 0 2 2 2 0 Enterobacterial EspB protein DUF812 PF05667.11 KFQ97516.1 - 2.8 6.7 42.7 8 5.2 24.2 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF812) Spc7 PF08317.11 KFQ97516.1 - 2.9 6.7 44.4 1.6 7.5 19.1 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF948 PF06103.11 KFQ97516.1 - 3 8.2 12.4 39 4.6 0.1 4.6 1 1 4 5 5 4 0 Bacterial protein of unknown function (DUF948) HGTP_anticodon PF03129.20 KFQ97516.1 - 3.7 7.7 10.6 5.9 7.1 0.1 3.8 4 0 0 4 4 3 0 Anticodon binding domain FAM184 PF15665.5 KFQ97516.1 - 3.8 7.2 46.7 1.9 8.2 2.7 3.5 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B DUF4266 PF14086.6 KFQ97516.1 - 4.1 8.4 5.3 1.2 10.2 0.4 2.8 3 0 0 3 3 1 0 Domain of unknown function (DUF4266) CENP-F_leu_zip PF10473.9 KFQ97516.1 - 4.2 7.4 45.3 0.094 12.7 9.0 3.7 1 1 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.10 KFQ97516.1 - 7.4 6.7 32.3 1.4 9.1 10.7 3.6 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family JIP_LZII PF16471.5 KFQ97516.1 - 9.3 6.5 34.8 1.4 9.2 2.6 6.1 1 1 4 6 6 6 0 JNK-interacting protein leucine zipper II Glyco_transf_29 PF00777.18 KFQ97517.1 - 6.8e-81 271.6 0.0 1e-80 271.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) PTPLA PF04387.14 KFQ97518.1 - 4e-59 199.0 13.4 4.7e-59 198.8 13.4 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA VHS PF00790.19 KFQ97519.1 - 4e-44 149.9 1.7 5.7e-44 149.4 0.1 2.0 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.28 KFQ97519.1 - 4e-16 58.3 0.1 7.7e-16 57.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFQ97519.1 - 1.6e-12 46.9 0.0 2.9e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFQ97519.1 - 1.6e-11 43.9 0.0 2.9e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.20 KFQ97519.1 - 6.9e-05 22.5 1.7 0.00019 21.1 1.7 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif GAT PF03127.14 KFQ97519.1 - 0.021 15.1 3.7 0.055 13.8 3.7 1.8 1 0 0 1 1 1 0 GAT domain SH3_10 PF17902.1 KFQ97519.1 - 0.036 14.1 0.0 0.093 12.8 0.0 1.6 1 0 0 1 1 1 0 SH3 domain HEAT PF02985.22 KFQ97519.1 - 0.43 11.0 1.5 1.3 9.5 0.1 2.4 2 0 0 2 2 2 0 HEAT repeat Lectin_C PF00059.21 KFQ97520.1 - 2e-76 253.7 8.3 1e-24 87.3 0.2 4.8 5 0 0 5 5 5 4 Lectin C-type domain fn2 PF00040.19 KFQ97520.1 - 7.1e-15 55.0 12.2 8.8e-15 54.7 9.9 2.5 2 0 0 2 2 2 1 Fibronectin type II domain UL45 PF05473.12 KFQ97520.1 - 3e-09 36.8 0.2 9.3e-06 25.4 0.0 3.3 3 0 0 3 3 3 2 UL45 protein, carbohydrate-binding C-type lectin-like Ricin_B_lectin PF00652.22 KFQ97520.1 - 9.9e-09 35.5 0.1 2.3e-08 34.3 0.1 1.7 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Xlink PF00193.17 KFQ97520.1 - 4.9e-06 26.9 4.7 0.28 11.6 0.2 5.4 4 1 1 5 5 5 2 Extracellular link domain Chordopox_A33R PF05966.12 KFQ97520.1 - 0.0047 16.2 0.6 0.32 10.3 0.0 2.9 3 0 0 3 3 3 1 Chordopoxvirus A33R protein Lectin_C PF00059.21 KFQ97521.1 - 2.1e-161 527.0 50.2 9.1e-23 81.1 0.4 9.1 9 0 0 9 9 9 8 Lectin C-type domain UL45 PF05473.12 KFQ97521.1 - 5.2e-20 71.9 9.9 5.2e-06 26.3 0.0 6.4 4 1 2 6 6 6 4 UL45 protein, carbohydrate-binding C-type lectin-like fn2 PF00040.19 KFQ97521.1 - 3.1e-13 49.8 5.3 3.1e-13 49.8 5.3 3.5 3 0 0 3 3 3 1 Fibronectin type II domain Xlink PF00193.17 KFQ97521.1 - 1.2e-11 44.8 10.0 0.64 10.4 0.0 8.3 8 1 1 9 9 9 5 Extracellular link domain Ricin_B_lectin PF00652.22 KFQ97521.1 - 2.8e-07 30.8 2.2 2.8e-07 30.8 2.2 2.3 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Chordopox_A33R PF05966.12 KFQ97521.1 - 3.6e-06 26.4 14.7 0.21 10.9 0.2 6.4 7 0 0 7 7 7 4 Chordopoxvirus A33R protein Intimin_C PF07979.11 KFQ97521.1 - 0.00099 19.5 5.6 53 4.3 0.0 7.0 8 0 0 8 8 8 0 Intimin C-type lectin domain Lectin_C PF00059.21 KFQ97522.1 - 1.7e-79 263.6 13.7 1.8e-25 89.8 0.6 5.1 5 0 0 5 5 5 4 Lectin C-type domain fn2 PF00040.19 KFQ97522.1 - 1.6e-17 63.4 8.9 1.6e-17 63.4 8.9 2.7 2 0 0 2 2 2 1 Fibronectin type II domain Ricin_B_lectin PF00652.22 KFQ97522.1 - 5e-09 36.5 0.3 5e-09 36.5 0.3 2.5 3 0 0 3 3 3 1 Ricin-type beta-trefoil lectin domain UL45 PF05473.12 KFQ97522.1 - 1.2e-06 28.4 9.2 0.0057 16.3 0.5 4.6 3 1 1 4 4 4 3 UL45 protein, carbohydrate-binding C-type lectin-like Xlink PF00193.17 KFQ97522.1 - 2.9e-06 27.6 9.3 0.18 12.2 0.3 5.9 5 1 1 6 6 6 2 Extracellular link domain Chordopox_A33R PF05966.12 KFQ97522.1 - 0.00012 21.4 3.9 0.84 8.9 0.0 3.9 4 0 0 4 4 4 2 Chordopoxvirus A33R protein Adeno_E3_CR1 PF02440.15 KFQ97522.1 - 0.38 10.6 5.8 0.98 9.2 0.2 3.7 4 0 0 4 4 4 0 Adenovirus E3 region protein CR1 Lectin_C PF00059.21 KFQ97523.1 - 7.2e-77 255.1 11.4 2.1e-22 79.9 0.1 4.2 4 0 0 4 4 4 4 Lectin C-type domain fn2 PF00040.19 KFQ97523.1 - 2.1e-17 63.1 5.7 6.4e-17 61.6 5.7 1.9 1 0 0 1 1 1 1 Fibronectin type II domain Xlink PF00193.17 KFQ97523.1 - 5.4e-07 29.9 7.2 0.19 12.1 0.1 5.0 4 1 1 5 5 5 2 Extracellular link domain UL45 PF05473.12 KFQ97523.1 - 2.5e-06 27.3 3.1 0.00033 20.4 0.0 3.5 3 1 1 4 4 4 1 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.12 KFQ97523.1 - 1.3e-05 24.6 0.7 0.018 14.3 0.0 3.3 3 0 0 3 3 3 2 Chordopoxvirus A33R protein Intimin_C PF07979.11 KFQ97523.1 - 0.015 15.7 0.2 98 3.5 0.0 4.1 4 0 0 4 4 4 0 Intimin C-type lectin domain Adeno_E3_CR1 PF02440.15 KFQ97523.1 - 0.18 11.6 0.1 0.18 11.6 0.1 2.6 3 0 0 3 3 3 0 Adenovirus E3 region protein CR1 Prok-RING_2 PF14445.6 KFQ97523.1 - 1 9.6 9.4 6.8 7.0 0.1 4.0 4 0 0 4 4 4 0 Prokaryotic RING finger family 2 Lectin_C PF00059.21 KFQ97524.1 - 8.7e-18 65.0 0.3 8.7e-18 65.0 0.3 1.9 2 0 0 2 2 2 1 Lectin C-type domain MFS_Mycoplasma PF07672.13 KFQ97524.1 - 0.0051 16.1 0.1 0.0077 15.5 0.1 1.2 1 0 0 1 1 1 1 Mycoplasma MFS transporter LapA_dom PF06305.11 KFQ97524.1 - 0.0073 16.1 0.4 0.012 15.4 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Connexin PF00029.19 KFQ97524.1 - 0.022 14.5 0.2 0.035 13.9 0.2 1.2 1 0 0 1 1 1 0 Connexin DUF5305 PF17231.2 KFQ97524.1 - 0.044 13.2 0.0 0.059 12.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) OATP PF03137.20 KFQ97524.1 - 0.056 11.7 0.0 0.08 11.2 0.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4366 PF14283.6 KFQ97524.1 - 0.13 12.3 0.1 0.13 12.3 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) Lectin_C PF00059.21 KFQ97525.1 - 7.2e-157 512.5 56.5 1.1e-23 84.0 0.0 8.9 9 0 0 9 9 9 8 Lectin C-type domain fn2 PF00040.19 KFQ97525.1 - 4.1e-16 59.0 1.2 2.1e-15 56.7 1.2 2.4 1 0 0 1 1 1 1 Fibronectin type II domain UL45 PF05473.12 KFQ97525.1 - 5.4e-16 58.8 5.4 0.01 15.5 0.0 8.0 5 2 2 7 7 7 5 UL45 protein, carbohydrate-binding C-type lectin-like Xlink PF00193.17 KFQ97525.1 - 2.2e-08 34.4 9.1 0.62 10.5 0.1 8.2 8 0 0 8 8 8 2 Extracellular link domain Ricin_B_lectin PF00652.22 KFQ97525.1 - 2.2e-08 34.4 2.4 2.2e-08 34.4 2.4 2.4 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Intimin_C PF07979.11 KFQ97525.1 - 0.0003 21.2 6.8 26 5.3 0.0 7.3 7 0 0 7 7 7 0 Intimin C-type lectin domain DUF3301 PF11743.8 KFQ97525.1 - 0.72 9.6 2.4 4.6 7.0 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3301) Chordopox_A33R PF05966.12 KFQ97525.1 - 1.5 8.0 15.2 5 6.4 0.0 5.9 8 0 0 8 8 8 0 Chordopoxvirus A33R protein ZIP4_domain PF18292.1 KFQ97526.1 - 4.9e-61 205.5 5.4 1.5e-56 190.8 2.9 2.4 2 0 0 2 2 2 2 Zinc transporter ZIP4 domain Zip PF02535.22 KFQ97526.1 - 3.5e-56 190.8 9.7 5.7e-56 190.1 9.7 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter Tox-SGS PF15651.6 KFQ97526.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Salivary glad secreted protein domain toxin IL4 PF00727.18 KFQ97526.1 - 0.41 10.9 2.8 4.2 7.7 0.0 3.1 2 1 0 2 2 2 0 Interleukin 4 UPF0114 PF03350.16 KFQ97526.1 - 0.74 10.0 3.5 0.43 10.8 0.8 2.0 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 Guanylate_kin PF00625.21 KFQ97527.1 - 3.2e-50 170.3 0.2 6.8e-50 169.3 0.2 1.6 1 0 0 1 1 1 1 Guanylate kinase VGCC_beta4Aa_N PF12052.8 KFQ97527.1 - 5.3e-23 80.8 6.6 5.3e-23 80.8 6.6 2.9 3 0 0 3 3 3 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal SH3_1 PF00018.28 KFQ97527.1 - 0.0017 18.0 0.1 0.0064 16.1 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFQ97527.1 - 0.16 11.7 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Methyltr_RsmB-F PF01189.17 KFQ97528.1 - 1.2e-46 158.9 0.0 1.9e-46 158.3 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 KFQ97528.1 - 1e-08 35.1 0.0 1.8e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KFQ97528.1 - 4e-08 33.6 0.0 9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase PUA PF01472.20 KFQ97528.1 - 0.00033 20.6 0.1 0.00069 19.5 0.1 1.5 1 0 0 1 1 1 1 PUA domain DUF2431 PF10354.9 KFQ97528.1 - 0.00038 20.8 0.0 0.00068 20.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) PCMT PF01135.19 KFQ97528.1 - 0.002 17.9 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KFQ97528.1 - 0.003 18.2 0.1 0.051 14.3 0.1 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 KFQ97528.1 - 0.0036 16.9 0.0 0.008 15.8 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Ubie_methyltran PF01209.18 KFQ97528.1 - 0.026 13.9 0.0 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KFQ97528.1 - 0.063 12.7 0.1 1.6 8.2 0.1 2.3 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_11 PF08241.12 KFQ97528.1 - 0.14 12.9 0.0 1.2 9.8 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KFQ97528.1 - 0.14 11.7 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Arf PF00025.21 KFQ97529.1 - 4.4e-65 218.4 0.2 4.8e-65 218.3 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFQ97529.1 - 7.4e-16 58.4 0.1 9.7e-16 58.1 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFQ97529.1 - 3.2e-14 52.8 0.1 3.6e-14 52.7 0.1 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFQ97529.1 - 6.8e-13 48.4 0.1 9.2e-13 48.0 0.1 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFQ97529.1 - 5.1e-09 35.8 0.4 3e-06 26.7 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KFQ97529.1 - 2.9e-07 30.6 0.1 4e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFQ97529.1 - 3.6e-07 29.8 0.2 4.2e-07 29.6 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFQ97529.1 - 0.0019 17.8 0.1 0.027 14.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 KFQ97529.1 - 0.013 15.5 0.1 0.038 14.0 0.0 1.7 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.18 KFQ97529.1 - 0.085 12.4 0.6 0.35 10.4 0.5 1.9 1 1 1 2 2 2 0 Ferrous iron transport protein B Keratin PF02422.16 KFQ97532.1 - 5.6e-33 112.5 8.9 6.1e-33 112.4 8.9 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFQ97533.1 - 2e-32 110.7 15.3 5.7e-32 109.3 15.3 1.7 1 1 0 1 1 1 1 Keratin Keratin PF02422.16 KFQ97534.1 - 1.5e-34 117.5 7.4 1.7e-34 117.4 7.4 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFQ97535.1 - 8.5e-35 118.3 6.8 1.1e-34 118.0 6.8 1.2 1 0 0 1 1 1 1 Keratin Keratin_2_head PF16208.5 KFQ97535.1 - 5 7.2 26.9 5.7 7.1 26.9 1.1 1 0 0 1 1 1 0 Keratin type II head WD40 PF00400.32 KFQ97537.1 - 4.4e-17 62.1 9.7 0.00053 20.7 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ97537.1 - 0.00012 22.3 1.2 4.3 7.7 0.0 4.1 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFQ97537.1 - 0.011 14.4 0.0 1.2 7.7 0.1 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 WD40_like PF17005.5 KFQ97537.1 - 0.051 12.9 0.1 7.2 5.8 0.0 3.2 3 1 1 4 4 4 0 WD40-like domain PDEase_I PF00233.19 KFQ97538.1 - 1.1e-91 306.9 4.5 2e-91 306.0 4.5 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PAS_9 PF13426.7 KFQ97538.1 - 8.1e-15 55.0 0.0 2.1e-14 53.7 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 KFQ97538.1 - 4.6e-12 46.0 0.0 1.5e-11 44.3 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 KFQ97538.1 - 1.4e-07 31.7 0.0 3.1e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KFQ97538.1 - 1.1e-06 28.8 0.0 3e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 KFQ97538.1 - 4.2e-05 23.5 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 PAS domain OCRE PF17780.1 KFQ97539.1 - 3.2e-18 65.5 14.4 3.2e-18 65.5 14.4 2.7 3 0 0 3 3 3 1 OCRE domain G-patch PF01585.23 KFQ97539.1 - 1.2e-14 53.9 5.5 2.3e-14 53.0 5.5 1.5 1 0 0 1 1 1 1 G-patch domain FHA PF00498.26 KFQ97539.1 - 1.3e-13 51.1 0.1 3.3e-13 49.8 0.1 1.8 1 0 0 1 1 1 1 FHA domain G-patch_2 PF12656.7 KFQ97539.1 - 1.6e-06 28.1 1.0 1.6e-06 28.1 1.0 2.6 3 0 0 3 3 3 1 G-patch domain Yop-YscD_cpl PF16697.5 KFQ97539.1 - 7.3e-05 23.0 0.8 0.00055 20.2 0.0 2.7 3 0 0 3 3 3 1 Inner membrane component of T3SS, cytoplasmic domain CRF-BP PF05428.11 KFQ97540.1 - 4.9e-178 590.5 0.1 5.5e-178 590.3 0.1 1.0 1 0 0 1 1 1 1 Corticotropin-releasing factor binding protein (CRF-BP) S_100 PF01023.19 KFQ97541.1 - 1.9e-20 72.3 0.4 2.9e-20 71.7 0.4 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_7 PF13499.6 KFQ97541.1 - 1.4e-06 28.6 0.8 2e-06 28.1 0.8 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFQ97541.1 - 3.4e-06 26.2 1.6 3.3e-05 23.1 0.6 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KFQ97541.1 - 0.00035 20.3 0.8 0.053 13.5 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFQ97541.1 - 0.032 13.7 3.1 0.18 11.4 0.8 2.4 2 0 0 2 2 2 0 EF hand DUF826 PF05696.11 KFQ97541.1 - 0.086 12.9 0.2 0.13 12.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF826) EF-hand_8 PF13833.6 KFQ97541.1 - 0.12 12.2 1.9 0.35 10.8 1.9 2.0 1 1 0 1 1 1 0 EF-hand domain pair RasGAP PF00616.19 KFQ97542.1 - 2.2e-55 187.6 2.0 3e-55 187.2 0.0 2.3 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KFQ97542.1 - 5.5e-38 130.2 14.6 5.5e-38 130.2 14.6 3.3 4 0 0 4 4 4 1 RasGAP C-terminus IQ PF00612.27 KFQ97542.1 - 1.8e-20 70.7 7.6 7.3e-05 22.2 0.0 5.2 4 0 0 4 4 4 4 IQ calmodulin-binding motif CH PF00307.31 KFQ97542.1 - 5.1e-15 55.6 0.0 4.6e-14 52.5 0.0 2.9 2 0 0 2 2 2 1 Calponin homology (CH) domain SHD1 PF03983.12 KFQ97542.1 - 0.076 12.8 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 SLA1 homology domain 1, SHD1 FAST_1 PF06743.15 KFQ97542.1 - 0.17 11.9 0.6 1.2 9.2 0.1 2.8 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 7tm_1 PF00001.21 KFQ97543.1 - 9.5e-40 136.6 39.0 2.2e-38 132.1 39.0 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFQ97543.1 - 0.00089 19.0 28.6 0.00089 19.0 28.6 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx PRRSV_2b PF07069.11 KFQ97543.1 - 0.063 13.8 0.6 0.063 13.8 0.6 3.4 4 0 0 4 4 4 0 Porcine reproductive and respiratory syndrome virus 2b MFS_1 PF07690.16 KFQ97544.1 - 2.3e-34 118.9 30.0 4.1e-24 85.2 13.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFQ97544.1 - 1.7e-32 112.9 16.8 1.7e-29 103.0 2.6 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Pentapeptide_4 PF13599.6 KFQ97544.1 - 1.1e-06 28.7 8.7 2e-06 27.9 8.7 1.3 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 KFQ97544.1 - 0.00073 19.6 5.3 0.00073 19.6 5.3 2.0 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) MFS_4 PF06779.14 KFQ97544.1 - 0.00094 18.6 9.4 0.00094 18.6 9.4 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 KFQ97544.1 - 0.0029 16.2 11.7 0.0029 16.2 11.7 2.5 2 0 0 2 2 2 1 MFS/sugar transport protein Pentapeptide PF00805.22 KFQ97544.1 - 0.024 14.3 1.2 0.068 12.8 0.8 1.9 1 1 1 2 2 2 0 Pentapeptide repeats (8 copies) Neurensin PF14927.6 KFQ97544.1 - 0.084 12.6 0.4 0.78 9.5 0.0 2.4 2 0 0 2 2 2 0 Neurensin MFS_3 PF05977.13 KFQ97544.1 - 0.26 9.6 8.0 0.5 8.7 4.2 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector DUF1897 PF09005.10 KFQ97544.1 - 1.7 8.2 4.2 8.7 5.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1897) TLE_N PF03920.15 KFQ97546.1 - 3.3e-53 179.3 10.6 4.7e-53 178.8 10.6 1.2 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.32 KFQ97546.1 - 1.6e-16 60.4 18.7 0.015 16.2 0.8 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ97546.1 - 9.2e-08 32.3 0.0 0.12 12.6 0.0 4.3 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFQ97546.1 - 0.01 14.5 0.2 3.5 6.2 0.0 3.1 2 1 0 3 3 3 0 Nucleoporin Nup120/160 WD40_like PF17005.5 KFQ97546.1 - 0.016 14.6 0.0 7.3 5.8 0.2 2.7 2 1 0 3 3 3 0 WD40-like domain Cytochrom_D1 PF02239.16 KFQ97546.1 - 0.056 12.0 0.0 1.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Ribosomal_S18 PF01084.20 KFQ97546.1 - 0.17 12.1 0.3 0.32 11.2 0.3 1.4 1 0 0 1 1 1 0 Ribosomal protein S18 BAR_3 PF16746.5 KFQ97555.1 - 2.4e-60 204.2 10.9 4.3e-60 203.4 10.9 1.4 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KFQ97555.1 - 1e-08 35.6 0.0 8.3e-08 32.7 0.0 2.5 2 0 0 2 2 2 1 PH domain PID PF00640.23 KFQ97555.1 - 1.8e-07 31.3 0.3 5e-07 29.8 0.3 1.8 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFQ97555.1 - 5.6e-05 23.3 0.1 0.00013 22.1 0.1 1.6 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PH_9 PF15410.6 KFQ97555.1 - 0.0042 17.5 0.0 0.017 15.5 0.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.10 KFQ97555.1 - 0.0048 17.2 0.0 0.021 15.2 0.0 2.1 2 0 0 2 2 2 1 Plant pleckstrin homology-like region DUF3263 PF11662.8 KFQ97555.1 - 0.03 14.2 0.2 0.092 12.6 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3263) PH_17 PF18012.1 KFQ97555.1 - 0.078 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 PH domain WASH-7_N PF14745.6 KFQ97556.1 - 3.3e-239 795.2 22.4 3.3e-239 795.2 22.4 2.2 3 0 0 3 3 3 1 WASH complex subunit 7, N-terminal WASH-7_mid PF14744.6 KFQ97556.1 - 1.7e-174 579.9 9.0 1.7e-174 579.9 9.0 2.3 2 0 0 2 2 2 1 WASH complex subunit 7 WASH-7_C PF14746.6 KFQ97556.1 - 1e-76 256.5 3.8 3.8e-76 254.7 3.8 2.1 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal NSs PF11073.8 KFQ97556.1 - 0.099 12.1 0.0 0.37 10.2 0.0 1.9 2 0 0 2 2 2 0 Rift valley fever virus non structural protein (NSs) like Aldedh PF00171.22 KFQ97557.1 - 1.6e-173 577.5 0.0 2e-173 577.2 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Formyl_trans_N PF00551.19 KFQ97557.1 - 2.7e-45 154.3 0.0 6e-45 153.2 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 KFQ97557.1 - 3.4e-15 56.1 0.0 8.6e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain PP-binding PF00550.25 KFQ97557.1 - 4.4e-05 23.8 0.0 8.9e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF1487 PF07368.11 KFQ97557.1 - 0.0057 16.1 0.0 0.017 14.6 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) DUF4598 PF15370.6 KFQ97558.1 - 2.7e-15 56.8 2.1 3.5e-15 56.4 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) Sigma70_r1_1 PF03979.14 KFQ97558.1 - 0.017 15.2 6.9 0.037 14.1 6.8 1.6 1 1 0 1 1 1 0 Sigma-70 factor, region 1.1 MgtE PF01769.16 KFQ97559.1 - 2.2e-51 173.4 12.2 6e-30 104.2 0.9 3.0 4 0 0 4 4 4 2 Divalent cation transporter DUF3262 PF11660.8 KFQ97559.1 - 0.39 11.1 6.6 17 5.9 0.6 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3262) Sulfotransfer_2 PF03567.14 KFQ97560.1 - 4.3e-69 233.2 8.3 5.6e-69 232.9 8.3 1.1 1 0 0 1 1 1 1 Sulfotransferase family Pyr_redox_2 PF07992.14 KFQ97561.1 - 2.7e-36 125.3 0.0 4.1e-36 124.7 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFQ97561.1 - 6.4e-27 94.0 0.0 1.1e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFQ97561.1 - 6.1e-15 55.5 0.1 1.7e-14 54.1 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFQ97561.1 - 6.7e-08 32.1 0.0 1.6e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Piwi PF02171.17 KFQ97561.1 - 0.069 12.4 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Piwi domain CBFD_NFYB_HMF PF00808.23 KFQ97562.1 - 4e-29 100.7 0.6 6e-29 100.1 0.6 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFQ97562.1 - 6.5e-06 26.5 0.0 9.8e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KFQ97562.1 - 0.0014 18.6 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.6 KFQ97562.1 - 0.0032 17.6 0.0 0.005 16.9 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 KFQ97562.1 - 0.12 12.8 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Bromo_TP PF07524.13 KFQ97562.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated Glyco_transf_8 PF01501.20 KFQ97563.1 - 8.9e-52 176.2 0.0 1.1e-51 175.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KFQ97563.1 - 0.0001 21.8 0.1 0.00023 20.7 0.1 1.6 1 1 1 2 2 2 1 Glucosyltransferase 24 UDG PF03167.19 KFQ97564.1 - 2e-18 66.8 0.0 3e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily GAGA_bind PF06217.12 KFQ97564.1 - 0.28 11.4 3.9 0.49 10.6 3.9 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family HSP90 PF00183.18 KFQ97565.1 - 3.3e-229 762.1 28.8 5.6e-229 761.3 28.8 1.3 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KFQ97565.1 - 4.8e-15 56.0 0.4 9.4e-15 55.1 0.4 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFQ97565.1 - 3.9e-12 46.2 0.3 1.3e-11 44.5 0.3 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AbiJ_NTD5 PF18865.1 KFQ97565.1 - 0.088 12.6 1.2 0.21 11.4 0.2 2.2 2 0 0 2 2 2 0 AbiJ N-terminal domain 5 MH1 PF03165.16 KFQ97565.1 - 0.25 11.6 1.8 0.86 9.8 0.0 2.8 3 0 0 3 3 3 0 MH1 domain 5_nucleotid PF05761.14 KFQ97566.1 - 3.6e-155 517.3 7.2 4.1e-155 517.2 7.2 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.6 KFQ97566.1 - 1.2e-05 25.5 0.3 0.00048 20.3 0.0 3.1 3 1 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Mu-transpos_C PF09299.11 KFQ97566.1 - 0.048 13.6 0.6 0.79 9.7 0.1 3.1 3 0 0 3 3 3 0 Mu transposase, C-terminal Hydrolase PF00702.26 KFQ97566.1 - 0.099 12.9 0.0 0.23 11.7 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Fasciclin PF02469.22 KFQ97567.1 - 4.8e-126 414.8 1.1 2.7e-23 82.6 0.2 7.3 7 0 0 7 7 7 7 Fasciclin domain EGF_3 PF12947.7 KFQ97567.1 - 3.3e-63 209.6 411.4 4.2e-10 39.6 14.6 25.6 25 1 0 25 25 25 16 EGF domain Xlink PF00193.17 KFQ97567.1 - 1.7e-27 95.6 0.4 1.7e-27 95.6 0.4 5.0 5 1 0 5 5 5 1 Extracellular link domain EGF PF00008.27 KFQ97567.1 - 0.0001 22.5 22.7 0.00028 21.1 6.3 26.7 26 1 0 26 26 26 16 EGF-like domain FXa_inhibition PF14670.6 KFQ97567.1 - 0.0011 19.2 26.1 0.0025 18.1 9.2 26.9 17 6 6 23 23 23 9 Coagulation Factor Xa inhibitory site Laminin_EGF PF00053.24 KFQ97567.1 - 0.0017 18.4 12.0 0.0017 18.4 12.0 30.3 13 6 16 30 30 30 2 Laminin EGF domain EGF_MSP1_1 PF12946.7 KFQ97567.1 - 0.0061 16.6 6.4 0.0061 16.6 6.4 23.7 24 0 0 24 24 24 7 MSP1 EGF domain 1 Biopterin_H PF00351.21 KFQ97568.1 - 4.1e-177 588.2 0.0 5.3e-177 587.8 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 KFQ97568.1 - 1.2e-09 37.8 0.0 2.7e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 KFQ97568.1 - 0.0006 20.4 0.1 0.0038 17.8 0.0 2.1 2 0 0 2 2 2 1 ACT domain Biopterin_H PF00351.21 KFQ97569.1 - 4e-173 575.0 1.1 4.8e-173 574.8 1.1 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase Insulin PF00049.18 KFQ97570.1 - 4.9e-15 56.3 5.9 2.6e-12 47.6 5.9 2.2 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.14 KFQ97570.1 - 0.12 12.4 2.0 5.2 7.2 0.1 2.3 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Pro-MCH PF05824.12 KFQ97571.1 - 4e-47 158.1 0.0 6.3e-47 157.4 0.0 1.3 1 0 0 1 1 1 1 Pro-melanin-concentrating hormone (Pro-MCH) Peptidase_C54 PF03416.19 KFQ97572.1 - 0.062 12.7 0.1 0.69 9.3 0.1 2.2 2 0 0 2 2 2 0 Peptidase family C54 WD40 PF00400.32 KFQ97573.1 - 1.1e-14 54.6 1.0 5.3e-05 23.9 0.1 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ97573.1 - 0.00028 21.1 0.0 0.0062 16.8 0.0 2.9 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain CCDC53 PF10152.9 KFQ97574.1 - 1.5e-49 168.3 0.8 1.9e-49 168.0 0.8 1.1 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex Frag1 PF10277.9 KFQ97575.1 - 6.2e-43 146.9 15.0 6.8e-43 146.7 15.0 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Stealth_CR2 PF11380.8 KFQ97576.1 - 2.2e-45 153.3 0.4 2.2e-45 153.3 0.4 2.8 3 0 0 3 3 3 1 Stealth protein CR2, conserved region 2 GlcNAc-1_reg PF18440.1 KFQ97576.1 - 6.6e-45 151.3 0.1 2e-44 149.7 0.1 1.9 1 0 0 1 1 1 1 Putative GlcNAc-1 phosphotransferase regulatory domain Stealth_CR4 PF17103.5 KFQ97576.1 - 3.7e-24 84.4 3.0 9e-24 83.1 1.7 2.3 2 0 0 2 2 2 1 Stealth protein CR4, conserved region 4 Stealth_CR3 PF17102.5 KFQ97576.1 - 7.4e-19 67.4 7.0 1.9e-18 66.1 7.0 1.8 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Notch PF00066.17 KFQ97576.1 - 1.6e-15 57.2 31.9 5.1e-09 36.4 12.6 2.4 2 0 0 2 2 2 2 LNR domain Stealth_CR1 PF17101.5 KFQ97576.1 - 8.3e-12 44.6 0.0 1.9e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 DMAP_binding PF06464.11 KFQ97576.1 - 4.9e-11 43.4 0.2 1.5e-10 41.8 0.2 1.9 1 0 0 1 1 1 1 DMAP1-binding Domain EF-hand_1 PF00036.32 KFQ97576.1 - 0.023 14.2 0.0 0.072 12.7 0.0 1.9 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 KFQ97576.1 - 0.11 13.0 0.0 0.82 10.2 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 KFQ97576.1 - 0.14 11.7 0.1 0.42 10.2 0.1 1.9 1 0 0 1 1 1 0 EF hand CDP-OH_P_transf PF01066.21 KFQ97577.1 - 1.9e-12 47.8 3.6 1.3e-11 45.1 0.0 3.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase I-set PF07679.16 KFQ97578.1 - 1.1e-94 310.7 4.1 1.4e-19 69.9 0.0 7.7 8 0 0 8 8 7 7 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ97578.1 - 9.2e-63 208.8 3.0 2.2e-14 53.8 0.1 7.6 7 0 0 7 7 7 7 Immunoglobulin domain fn3 PF00041.21 KFQ97578.1 - 1.3e-43 147.2 0.9 3.1e-13 49.9 0.0 5.1 5 0 0 5 5 5 3 Fibronectin type III domain Ig_2 PF13895.6 KFQ97578.1 - 2.8e-42 142.9 1.5 1.2e-09 38.4 0.1 7.6 7 1 0 7 7 7 7 Immunoglobulin domain ig PF00047.25 KFQ97578.1 - 1.6e-36 124.4 4.4 8.2e-10 38.7 0.0 7.7 8 0 0 8 8 7 6 Immunoglobulin domain THB PF18362.1 KFQ97578.1 - 2.3e-21 75.1 0.4 9.4e-21 73.1 0.0 2.1 2 0 0 2 2 2 1 Tri-helix bundle domain V-set PF07686.17 KFQ97578.1 - 5.6e-17 61.9 7.1 0.036 14.2 0.1 9.6 7 3 0 7 7 7 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFQ97578.1 - 1e-10 41.6 0.4 0.065 13.3 0.0 6.0 6 0 0 6 6 6 3 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFQ97578.1 - 3.4e-07 30.6 2.9 1.9 9.0 0.1 6.4 7 0 0 7 7 7 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 KFQ97578.1 - 3.3e-06 27.4 8.9 2.9 8.3 0.0 6.9 7 0 0 7 7 7 1 Immunoglobulin C1-set domain Pur_ac_phosph_N PF16656.5 KFQ97578.1 - 0.00034 21.1 3.0 1.2 9.7 0.2 5.1 5 1 0 5 5 4 1 Purple acid Phosphatase, N-terminal domain DUF4251 PF14059.6 KFQ97578.1 - 0.0028 17.6 2.1 6.5 6.7 0.1 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4251) Ig_4 PF16680.5 KFQ97578.1 - 0.11 12.8 13.0 0.72 10.2 0.1 5.6 6 2 0 6 6 6 0 T-cell surface glycoprotein CD3 delta chain V-set_CD47 PF08204.11 KFQ97578.1 - 0.11 12.4 0.7 14 5.7 0.1 3.5 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain LIFR_D2 PF17971.1 KFQ97578.1 - 0.11 12.6 0.0 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Leukemia inhibitory factor receptor D2 domain fn3_2 PF16893.5 KFQ97578.1 - 0.13 12.4 0.0 23 5.2 0.0 2.9 2 0 0 2 2 2 0 Fibronectin type III domain Ets PF00178.22 KFQ97579.1 - 4.2e-23 81.6 0.4 7.3e-23 80.8 0.4 1.4 1 0 0 1 1 1 1 Ets-domain PARP PF00644.20 KFQ97580.1 - 6.6e-39 133.5 0.7 2.2e-38 131.8 0.7 1.7 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain p450 PF00067.22 KFQ97581.1 - 5.1e-91 305.7 1.0 2.3e-71 240.9 0.2 2.0 2 0 0 2 2 2 2 Cytochrome P450 MCM_bind PF09739.9 KFQ97581.1 - 0.1 11.1 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Pkinase PF00069.25 KFQ97582.1 - 1.4e-51 175.4 0.0 3.2e-51 174.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ97582.1 - 3.9e-24 85.4 0.0 6.6e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFQ97582.1 - 1.1e-06 28.2 0.0 4.6e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFQ97582.1 - 0.0041 15.9 1.4 0.011 14.5 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFQ97582.1 - 0.013 15.5 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KFQ97582.1 - 0.014 14.4 0.1 0.021 13.8 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase FTA2 PF13095.6 KFQ97582.1 - 0.15 11.7 0.1 16 5.0 0.0 2.5 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 NAC PF01849.18 KFQ97584.1 - 3.6e-14 52.5 0.7 5.9e-14 51.8 0.7 1.4 1 0 0 1 1 1 1 NAC domain Ank_2 PF12796.7 KFQ97585.1 - 1.4e-26 92.8 0.0 2.7e-13 50.3 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFQ97585.1 - 3.8e-21 74.9 0.2 6.4e-07 29.5 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ97585.1 - 8.8e-20 68.7 0.0 5.1e-06 26.4 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KFQ97585.1 - 4.3e-19 68.1 0.0 6.5e-06 26.3 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KFQ97585.1 - 6.4e-19 68.1 0.2 4.6e-08 33.4 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DUF1296 PF06972.11 KFQ97585.1 - 0.31 11.2 1.3 2.9 8.1 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1296) Kelch_1 PF01344.25 KFQ97586.1 - 2.7e-49 164.5 7.4 5.3e-11 41.9 0.1 5.6 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 KFQ97586.1 - 1.4e-30 105.5 2.3 3.9e-30 104.0 1.6 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 KFQ97586.1 - 4.1e-29 101.0 0.2 8.2e-29 100.1 0.2 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.6 KFQ97586.1 - 3e-23 81.3 5.2 2.3e-05 24.5 0.0 5.9 2 1 4 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KFQ97586.1 - 6.6e-21 73.4 2.3 0.00017 21.4 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 KFQ97586.1 - 1.1e-19 70.2 4.0 5.1e-05 23.4 0.0 6.1 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 KFQ97586.1 - 2.9e-19 68.8 0.6 3e-07 30.3 0.0 5.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KFQ97586.1 - 1.5e-13 50.4 6.5 8.5e-07 28.8 0.0 5.3 6 0 0 6 6 6 3 Kelch motif DUF3342 PF11822.8 KFQ97586.1 - 0.00028 21.0 0.6 0.0017 18.5 0.0 2.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3342) PFU PF09070.11 KFQ97586.1 - 0.028 14.7 0.0 0.073 13.3 0.0 1.7 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) GTP_EFTU PF00009.27 KFQ97587.1 - 1.1e-66 224.1 0.0 1.7e-66 223.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KFQ97587.1 - 4.6e-29 100.3 0.0 2e-28 98.3 0.0 2.2 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KFQ97587.1 - 4.4e-24 84.3 0.0 9.6e-24 83.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 KFQ97587.1 - 1.3e-13 50.7 0.0 2.9e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV RF3_C PF16658.5 KFQ97587.1 - 1.5e-08 34.5 0.0 2.4e-07 30.6 0.0 2.3 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 KFQ97587.1 - 2.6e-08 34.1 0.0 5.8e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFQ97587.1 - 0.00012 22.1 0.0 0.00026 21.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AvrPtoB_bdg PF16847.5 KFQ97587.1 - 0.016 15.6 0.1 0.22 12.0 0.0 2.7 3 0 0 3 3 3 0 Avirulence AvrPtoB, BAK1-binding domain FeoB_N PF02421.18 KFQ97587.1 - 0.027 14.0 0.0 0.14 11.7 0.0 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B AIG1 PF04548.16 KFQ97587.1 - 0.057 12.7 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 AIG1 family Ribosomal_S8e PF01201.22 KFQ97588.1 - 3e-50 169.9 11.7 3e-50 169.9 11.7 1.9 1 1 1 2 2 2 1 Ribosomal protein S8e MFS_1 PF07690.16 KFQ97592.1 - 2.1e-34 119.0 53.4 2.5e-32 112.2 39.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFQ97592.1 - 1.3e-11 44.0 22.5 2e-09 36.8 22.2 3.3 2 1 0 2 2 2 1 MFS_1 like family Spin-Ssty PF02513.17 KFQ97593.1 - 1.2e-76 252.3 7.8 6.5e-28 96.2 0.2 3.2 3 0 0 3 3 3 3 Spin/Ssty Family Ras PF00071.22 KFQ97594.1 - 1.3e-50 171.2 0.1 1.5e-50 170.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ97594.1 - 1.7e-17 63.7 0.0 3.4e-17 62.8 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ97594.1 - 5.7e-07 29.1 0.0 8.2e-07 28.6 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFQ97594.1 - 0.00026 21.0 0.0 0.00053 20.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFQ97594.1 - 0.00051 20.0 2.1 0.5 10.3 0.2 2.3 1 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KFQ97594.1 - 0.0026 17.2 0.8 0.0098 15.3 0.8 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MeaB PF03308.16 KFQ97594.1 - 0.0049 15.9 0.6 0.38 9.7 0.3 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KFQ97594.1 - 0.026 14.9 0.1 0.04 14.3 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KFQ97594.1 - 0.049 13.3 0.6 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KFQ97594.1 - 0.079 13.2 0.3 0.36 11.1 0.3 2.2 1 1 0 1 1 1 0 AAA domain MMR_HSR1_Xtn PF16897.5 KFQ97594.1 - 0.095 12.7 0.1 0.32 11.0 0.1 1.8 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain DUF2408 PF10303.9 KFQ97594.1 - 0.11 13.0 5.3 2 9.0 5.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2408) AAA_28 PF13521.6 KFQ97594.1 - 0.15 12.3 0.1 0.34 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain Pkinase_Tyr PF07714.17 KFQ97595.1 - 4.2e-89 298.3 0.2 6.1e-89 297.7 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ97595.1 - 6.6e-49 166.6 0.0 1.1e-48 165.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFQ97595.1 - 9.7e-43 144.2 0.8 4.3e-21 74.8 0.1 2.5 2 0 0 2 2 2 2 SH2 domain Kdo PF06293.14 KFQ97595.1 - 0.00022 20.6 0.1 0.00037 19.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFQ97595.1 - 0.008 15.2 0.1 0.013 14.5 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain ECH_1 PF00378.20 KFQ97596.1 - 8.8e-59 198.8 0.1 9.7e-59 198.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFQ97596.1 - 3.5e-30 105.7 0.2 2.7e-29 102.7 0.2 1.8 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Vert_IL3-reg_TF PF06529.11 KFQ97597.1 - 4.2e-184 611.2 22.0 6.3e-184 610.7 22.0 1.3 1 0 0 1 1 1 1 Vertebrate interleukin-3 regulated transcription factor bZIP_2 PF07716.15 KFQ97597.1 - 1.2e-14 54.1 9.6 1.2e-14 54.1 9.6 2.9 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 KFQ97597.1 - 0.00026 21.0 7.1 0.00026 21.0 7.1 3.5 3 0 0 3 3 3 1 bZIP transcription factor Lectin_N PF03954.14 KFQ97597.1 - 3.6 7.3 6.0 1.1 8.9 0.3 2.8 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain Pkinase_Tyr PF07714.17 KFQ97598.1 - 2e-86 289.5 0.0 2.6e-86 289.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ97598.1 - 3.9e-37 128.1 0.0 5.6e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kringle PF00051.18 KFQ97598.1 - 1e-25 89.8 2.5 5.4e-25 87.5 2.5 2.2 2 0 0 2 2 2 1 Kringle domain I-set PF07679.16 KFQ97598.1 - 6e-18 64.7 0.0 1.1e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ97598.1 - 1.9e-15 57.2 2.1 2.1e-15 57.0 0.1 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Fz PF01392.22 KFQ97598.1 - 1.6e-11 44.8 2.7 1.6e-11 44.8 2.7 2.1 2 0 0 2 2 2 1 Fz domain Ig_2 PF13895.6 KFQ97598.1 - 6.4e-09 36.0 0.0 2e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFQ97598.1 - 2.8e-07 30.7 0.3 3.8e-05 23.8 0.3 2.4 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFQ97598.1 - 5.5e-07 29.7 0.0 1.5e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain DUF2149 PF09919.9 KFQ97598.1 - 0.14 12.5 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) TMEM154 PF15102.6 KFQ97598.1 - 0.16 11.9 0.1 0.16 11.9 0.1 2.1 3 0 0 3 3 3 0 TMEM154 protein family Aminotran_1_2 PF00155.21 KFQ97599.1 - 8.2e-43 147.0 0.0 9.4e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II PAD PF03068.15 KFQ97599.1 - 0.058 12.4 0.0 0.086 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) Cys_Met_Meta_PP PF01053.20 KFQ97599.1 - 0.058 11.9 0.0 0.094 11.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PBD PF00786.28 KFQ97600.1 - 1.1e-05 25.7 0.1 1.5e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 P21-Rho-binding domain Pentapeptide_4 PF13599.6 KFQ97604.1 - 0.068 13.3 0.0 0.18 12.0 0.0 1.7 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) Homeobox_KN PF05920.11 KFQ97605.1 - 3.7e-17 61.9 0.4 5.5e-17 61.4 0.4 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFQ97605.1 - 9.7e-09 34.9 2.3 1.2e-08 34.7 2.3 1.1 1 0 0 1 1 1 1 Homeodomain MRP-S32 PF10210.9 KFQ97605.1 - 0.016 15.7 2.1 0.019 15.5 2.1 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 Cas_Cmr5 PF09701.10 KFQ97605.1 - 0.051 13.9 0.1 0.056 13.7 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr5) Homez PF11569.8 KFQ97605.1 - 0.054 13.0 0.1 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez zf-CHCC PF10276.9 KFQ97606.1 - 2.2e-18 66.0 0.7 2.9e-18 65.6 0.7 1.2 1 0 0 1 1 1 1 Zinc-finger domain Acyltransferase PF01553.21 KFQ97607.1 - 5.5e-17 61.6 0.0 9.1e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase EF-hand_8 PF13833.6 KFQ97607.1 - 5.3e-12 45.4 5.1 1.5e-07 31.1 0.1 3.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFQ97607.1 - 7.7e-12 44.1 1.8 0.00044 20.0 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 KFQ97607.1 - 1.7e-09 36.5 3.7 0.00018 20.8 0.2 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 KFQ97607.1 - 1.7e-08 34.8 3.1 7.4e-05 23.1 0.1 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFQ97607.1 - 0.00032 20.0 1.9 0.016 14.7 0.4 3.0 3 0 0 3 3 3 1 EF hand EF-hand_4 PF12763.7 KFQ97607.1 - 0.0049 16.8 0.4 0.53 10.3 0.1 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand PrgI PF12666.7 KFQ97607.1 - 0.12 13.1 1.0 0.3 11.8 1.0 1.7 1 0 0 1 1 1 0 PrgI family protein CLPTM1 PF05602.12 KFQ97608.1 - 2.4e-128 428.8 3.2 2.8e-128 428.6 3.2 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Telomerase_RBD PF12009.8 KFQ97609.1 - 5.1e-41 139.9 5.5 1.6e-40 138.3 5.5 1.9 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 KFQ97609.1 - 3.9e-14 52.7 0.3 4.9e-09 36.0 0.0 2.7 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) TERT_thumb PF17984.1 KFQ97609.1 - 0.00076 19.4 1.1 0.0019 18.1 1.1 1.6 1 0 0 1 1 1 1 Telomerase reverse transcriptase thumb DNA binding domain Lipoprotein_11 PF03260.13 KFQ97609.1 - 0.008 15.6 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Lepidopteran low molecular weight (30 kD) lipoprotein UBA2_C PF16195.5 KFQ97609.1 - 0.087 13.5 4.1 0.2 12.4 4.1 1.5 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus zf-IS66 PF13005.7 KFQ97609.1 - 0.097 13.1 0.1 0.4 11.1 0.1 2.1 1 0 0 1 1 1 0 zinc-finger binding domain of transposase IS66 SNF PF00209.18 KFQ97610.1 - 1e-174 582.1 29.0 1.4e-174 581.7 29.0 1.2 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 KFQ97611.1 - 9.7e-177 588.8 29.2 1.2e-176 588.5 29.2 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family PIN_3 PF13470.6 KFQ97612.1 - 0.27 12.0 2.2 0.64 10.8 1.9 1.9 1 1 0 1 1 1 0 PIN domain AAA_23 PF13476.6 KFQ97612.1 - 0.64 10.5 8.1 0.99 9.9 8.1 1.3 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 KFQ97612.1 - 1.2 8.6 8.5 1.6 8.2 8.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAD_binding_2 PF00890.24 KFQ97613.1 - 5e-126 421.2 2.3 6.1e-126 420.9 2.3 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KFQ97613.1 - 4e-38 130.3 0.0 6.1e-38 129.7 0.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KFQ97613.1 - 9.7e-06 25.0 0.4 0.0022 17.3 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFQ97613.1 - 1.5e-05 24.4 0.4 0.11 11.8 0.1 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 KFQ97613.1 - 0.00039 19.6 3.2 0.066 12.3 2.2 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KFQ97613.1 - 0.0044 16.3 0.1 0.0068 15.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFQ97613.1 - 0.022 14.3 0.0 0.12 11.9 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KFQ97613.1 - 0.15 10.7 1.0 0.82 8.3 0.1 2.5 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.6 KFQ97613.1 - 0.59 9.3 1.6 3.4 6.8 0.5 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lyase_1 PF00206.20 KFQ97614.1 - 4e-123 410.8 0.1 5.1e-123 410.4 0.1 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KFQ97614.1 - 7.9e-28 96.7 0.1 4e-27 94.4 0.0 2.2 2 0 0 2 2 2 1 Fumarase C C-terminus Snf7 PF03357.21 KFQ97615.1 - 4.1e-51 173.0 20.9 4.7e-51 172.8 20.9 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 KFQ97615.1 - 0.00086 19.7 1.6 0.00086 19.7 1.6 2.8 1 1 2 3 3 3 1 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 KFQ97615.1 - 0.03 14.6 2.7 0.031 14.5 0.7 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Prefoldin_2 PF01920.20 KFQ97615.1 - 0.066 13.2 21.8 0.58 10.1 0.8 3.5 2 1 1 3 3 3 0 Prefoldin subunit Alpha-E PF04168.12 KFQ97615.1 - 0.08 12.7 1.2 0.13 12.0 0.8 1.4 1 1 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. Hydantoinase_B PF02538.14 KFQ97615.1 - 0.19 10.1 1.3 0.21 10.0 1.3 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase BCDHK_Adom3 PF10436.9 KFQ97615.1 - 0.21 11.4 2.7 0.29 11.0 2.7 1.2 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase GvpK PF05121.12 KFQ97615.1 - 1.2 9.2 11.7 1.2 9.2 2.6 3.1 2 1 0 3 3 3 0 Gas vesicle protein K DUF848 PF05852.11 KFQ97615.1 - 1.6 8.8 9.6 0.77 9.9 6.7 1.9 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Endotoxin_N PF03945.14 KFQ97615.1 - 1.6 8.3 6.4 3.3 7.4 6.4 1.5 1 1 0 1 1 1 0 delta endotoxin, N-terminal domain YlqD PF11068.8 KFQ97615.1 - 3 8.2 18.2 10 6.5 5.3 2.1 1 1 1 2 2 2 0 YlqD protein CorA PF01544.18 KFQ97615.1 - 3.2 7.0 15.1 5.2 6.3 9.5 2.8 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Atg14 PF10186.9 KFQ97615.1 - 9.4 5.2 11.0 12 4.8 11.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BAG PF02179.16 KFQ97616.1 - 3.8e-09 36.8 3.7 1.3e-08 35.1 3.7 1.9 1 1 0 1 1 1 1 BAG domain ubiquitin PF00240.23 KFQ97616.1 - 1.3e-08 34.5 0.1 1.3e-08 34.5 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin family PHTB1_C PF14728.6 KFQ97616.1 - 0.00064 18.9 0.8 0.00078 18.6 0.8 1.1 1 0 0 1 1 1 1 PTHB1 C-terminus Ubiquitin_5 PF18037.1 KFQ97616.1 - 0.0015 18.8 2.8 0.0044 17.4 0.0 2.3 2 1 0 2 2 2 1 Ubiquitin-like domain TRPM_tetra PF16519.5 KFQ97616.1 - 0.0024 17.9 2.5 0.65 10.1 0.6 3.4 2 1 2 4 4 4 1 Tetramerisation domain of TRPM EzrA PF06160.12 KFQ97616.1 - 0.0031 15.8 4.6 0.0041 15.3 4.6 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Ubiquitin_2 PF14560.6 KFQ97616.1 - 0.0059 17.0 0.7 1.2 9.7 0.0 2.7 2 2 0 2 2 2 1 Ubiquitin-like domain Zwint PF15556.6 KFQ97616.1 - 0.018 14.5 5.6 0.046 13.2 3.7 2.0 1 1 1 2 2 2 0 ZW10 interactor DASH_Duo1 PF08651.10 KFQ97616.1 - 0.02 14.6 2.1 0.32 10.8 0.5 2.6 2 0 0 2 2 2 0 DASH complex subunit Duo1 SesA PF17107.5 KFQ97616.1 - 0.024 14.8 2.7 0.045 13.9 2.7 1.5 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases YPEB PF14620.6 KFQ97616.1 - 0.064 12.6 2.8 0.048 13.0 1.2 1.5 2 0 0 2 2 2 0 YpeB sporulation Ubiquitin_4 PF18036.1 KFQ97616.1 - 0.084 12.9 0.4 0.61 10.2 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2247 PF10004.9 KFQ97616.1 - 0.084 12.6 1.5 0.11 12.2 1.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) PIN_8 PF18476.1 KFQ97616.1 - 0.1 12.5 3.8 0.16 11.8 3.8 1.2 1 0 0 1 1 1 0 PIN like domain MscS_porin PF12795.7 KFQ97616.1 - 0.19 11.2 7.3 0.71 9.4 0.2 2.5 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain Prefoldin PF02996.17 KFQ97616.1 - 0.31 10.9 6.9 0.89 9.5 1.6 2.7 1 1 1 2 2 2 0 Prefoldin subunit GrpE PF01025.19 KFQ97616.1 - 1.1 9.0 8.6 2.4 7.8 8.6 1.7 1 1 0 1 1 1 0 GrpE DASH_Dad2 PF08654.10 KFQ97616.1 - 1.1 9.7 7.2 0.47 10.9 1.5 2.6 2 1 1 3 3 2 0 DASH complex subunit Dad2 Spectrin PF00435.21 KFQ97616.1 - 1.4 9.4 8.0 6 7.4 4.7 2.8 3 1 0 3 3 3 0 Spectrin repeat DUF848 PF05852.11 KFQ97616.1 - 1.4 9.0 6.0 1.5 8.9 4.3 1.8 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Laminin_II PF06009.12 KFQ97616.1 - 1.6 8.7 6.7 1.9 8.5 0.9 2.8 2 1 1 3 3 3 0 Laminin Domain II DUF4140 PF13600.6 KFQ97616.1 - 2.1 8.8 5.5 3.7 8.1 2.0 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) FlaC_arch PF05377.11 KFQ97616.1 - 2.2 8.8 5.8 8.5 6.9 3.0 3.2 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Seryl_tRNA_N PF02403.22 KFQ97616.1 - 3.8 7.8 13.0 2.3 8.5 2.9 2.6 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF1033 PF06279.11 KFQ97617.1 - 0.00075 19.7 0.3 0.0017 18.5 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1033) DUF3246 PF11596.8 KFQ97617.1 - 1.9 7.9 6.7 3.7 6.9 6.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) KH_1 PF00013.29 KFQ97618.1 - 6.9e-56 186.0 13.4 3.7e-19 68.3 0.4 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KFQ97618.1 - 1e-16 60.5 6.4 7e-06 25.8 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KFQ97618.1 - 2.7e-09 36.8 2.9 0.0032 17.3 0.4 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KFQ97618.1 - 2.8e-07 30.5 6.3 0.075 13.1 0.1 3.4 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 KFQ97618.1 - 6.1e-05 23.0 0.0 0.012 15.6 0.0 3.1 3 0 0 3 3 3 1 KH-like RNA-binding domain DUF370 PF04025.12 KFQ97618.1 - 0.0074 16.4 1.0 0.34 11.1 0.1 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF370) GETHR PF05671.11 KFQ97619.1 - 2.2e-08 33.3 34.7 0.0013 18.0 19.6 3.1 1 1 1 2 2 2 2 GETHR pentapeptide repeat (5 copies) MOSC_N PF03476.16 KFQ97620.1 - 1.9e-31 108.5 0.0 3.4e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 KFQ97620.1 - 5e-24 84.8 0.0 1e-23 83.8 0.0 1.5 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.19 KFQ97620.1 - 1.6e-22 80.0 0.0 3.4e-22 78.9 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Y_phosphatase PF00102.27 KFQ97621.1 - 1.1e-79 267.3 1.5 2.5e-79 266.2 1.5 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FERM_C PF09380.10 KFQ97621.1 - 5.3e-25 87.6 1.5 2e-24 85.8 1.5 2.1 1 0 0 1 1 1 1 FERM C-terminal PH-like domain PDZ PF00595.24 KFQ97621.1 - 8e-21 74.2 0.1 2.2e-20 72.8 0.0 1.8 2 0 0 2 2 2 1 PDZ domain FERM_M PF00373.18 KFQ97621.1 - 8.9e-21 74.5 0.2 2.4e-20 73.1 0.2 1.8 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 KFQ97621.1 - 2.1e-16 59.6 0.0 4.2e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 FERM N-terminal domain PDZ_6 PF17820.1 KFQ97621.1 - 8e-07 28.8 0.0 1.5e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain DSPc PF00782.20 KFQ97621.1 - 3.2e-05 23.8 0.1 7.6e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFQ97621.1 - 0.00036 20.6 0.0 0.00066 19.7 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFQ97621.1 - 0.00075 19.6 0.1 0.0017 18.5 0.1 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate PDZ_2 PF13180.6 KFQ97621.1 - 0.019 15.3 0.0 0.061 13.7 0.0 1.9 1 0 0 1 1 1 0 PDZ domain FERM_C PF09380.10 KFQ97622.1 - 1.3e-22 80.0 0.0 2.3e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 KFQ97622.1 - 1.1e-16 61.3 0.2 1.7e-16 60.7 0.2 1.3 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 KFQ97622.1 - 2.3e-14 53.1 0.1 1e-13 51.0 0.2 2.1 2 0 0 2 2 2 1 FERM N-terminal domain FA PF08736.11 KFQ97622.1 - 2.8e-13 49.7 10.7 6.7e-13 48.5 10.7 1.7 1 0 0 1 1 1 1 FERM adjacent (FA) AD PF09793.9 KFQ97622.1 - 0.19 11.9 0.0 0.41 10.8 0.0 1.6 1 0 0 1 1 1 0 Anticodon-binding domain DOMON PF03351.17 KFQ97623.1 - 4.9e-21 75.2 0.1 6.3e-21 74.9 0.1 1.1 1 0 0 1 1 1 1 DOMON domain AI-2E_transport PF01594.16 KFQ97624.1 - 2.5e-11 43.3 29.5 3.5e-10 39.6 18.3 4.0 4 2 0 4 4 4 2 AI-2E family transporter Tubulin_2 PF13809.6 KFQ97624.1 - 0.29 10.3 0.5 0.45 9.6 0.0 1.5 2 0 0 2 2 2 0 Tubulin like Vma12 PF11712.8 KFQ97624.1 - 4.9 7.2 5.6 3.1 7.9 2.9 2.1 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Sulfotransfer_2 PF03567.14 KFQ97625.1 - 8e-21 75.1 0.4 8e-21 75.1 0.4 1.6 2 0 0 2 2 2 1 Sulfotransferase family Topoisom_I_N PF02919.15 KFQ97625.1 - 0.15 11.5 5.6 0.21 11.1 5.6 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment YL1_C PF08265.11 KFQ97626.1 - 3.5e-12 45.9 0.9 7.1e-12 44.9 0.1 2.0 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Glycos_transf_2 PF00535.26 KFQ97628.1 - 5.3e-39 133.7 0.0 8.2e-39 133.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFQ97628.1 - 8.3e-30 103.6 3.3 1.4e-29 102.9 3.3 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 KFQ97628.1 - 2.9e-08 33.9 0.0 5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KFQ97628.1 - 1.3e-05 24.8 0.1 2.7e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.6 KFQ97628.1 - 4.2e-05 24.2 0.3 0.026 15.3 0.1 2.8 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Glyco_tranf_2_2 PF10111.9 KFQ97628.1 - 0.00033 20.2 0.0 0.00095 18.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Decorin_bind PF02352.15 KFQ97628.1 - 0.18 12.1 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 Decorin binding protein DUF4674 PF15719.5 KFQ97629.1 - 1.3e-72 243.9 14.3 1.4e-72 243.7 14.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4674) Rpr2 PF04032.16 KFQ97629.1 - 0.47 10.8 5.8 0.24 11.7 1.6 2.6 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain CREPT PF16566.5 KFQ97630.1 - 2e-58 196.7 1.0 2e-58 196.7 1.0 1.5 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour CTD_bind PF04818.13 KFQ97630.1 - 1e-22 80.7 0.4 4.6e-22 78.6 0.0 2.2 2 1 0 2 2 2 1 RNA polymerase II-binding domain. PhoU PF01895.19 KFQ97630.1 - 0.013 16.0 2.4 0.22 12.0 0.7 2.3 2 0 0 2 2 2 0 PhoU domain DIRP PF06584.13 KFQ97630.1 - 0.033 14.4 0.9 0.091 13.0 0.3 1.9 2 0 0 2 2 2 0 DIRP Com_YlbF PF06133.11 KFQ97630.1 - 0.065 13.9 1.6 0.27 11.9 0.5 2.4 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA FH2 PF02181.23 KFQ97631.1 - 6.4e-93 311.8 7.7 6.4e-93 311.8 7.7 2.2 2 1 0 2 2 2 1 Formin Homology 2 Domain LapA_dom PF06305.11 KFQ97642.1 - 0.0056 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain DUF3340 PF11818.8 KFQ97642.1 - 0.041 14.1 1.5 0.046 13.9 0.2 1.7 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) DUF3021 PF11457.8 KFQ97642.1 - 0.051 13.9 0.2 0.078 13.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) Insulin_TMD PF17870.1 KFQ97642.1 - 0.063 13.4 0.5 0.12 12.5 0.5 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Bax1-I PF01027.20 KFQ97643.1 - 5.1e-40 137.5 15.1 7.5e-40 137.0 15.1 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 ABC2_membrane_5 PF13346.6 KFQ97643.1 - 9.2 5.7 8.2 3.8e+02 0.5 7.4 2.6 1 1 0 1 1 1 0 ABC-2 family transporter protein Cadherin PF00028.17 KFQ97644.1 - 7.3e-72 237.9 5.7 3e-16 59.7 0.1 6.3 6 0 0 6 6 6 6 Cadherin domain Fn3_assoc PF13287.6 KFQ97644.1 - 0.053 13.7 1.2 2.7 8.2 0.1 3.4 3 0 0 3 3 3 0 Fn3 associated Cadherin_2 PF08266.12 KFQ97644.1 - 0.1 12.5 0.0 1.5 8.7 0.0 2.8 3 0 0 3 3 3 0 Cadherin-like SOR PF07682.11 KFQ97644.1 - 0.12 11.3 0.5 0.41 9.5 0.5 1.8 1 1 0 1 1 1 0 Sulphur oxygenase reductase Ferric_reduct PF01794.19 KFQ97644.1 - 0.24 11.5 0.6 0.73 10.0 0.1 1.9 2 0 0 2 2 2 0 Ferric reductase like transmembrane component Big_9 PF17963.1 KFQ97644.1 - 0.45 11.3 16.7 1.7 9.4 0.4 5.0 6 0 0 6 6 6 0 Bacterial Ig domain LRR_8 PF13855.6 KFQ97645.1 - 1e-23 82.8 0.2 3.1e-11 42.8 0.0 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFQ97645.1 - 3.5e-13 49.5 11.5 3.8e-06 27.1 1.5 3.1 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) I-set PF07679.16 KFQ97645.1 - 7.2e-11 42.0 0.0 1.1e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ97645.1 - 1.8e-09 38.1 0.0 2.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFQ97645.1 - 1.1e-07 32.0 0.0 1.7e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.33 KFQ97645.1 - 1.5e-06 27.9 3.1 1.7 9.5 0.1 5.1 5 0 0 5 5 5 2 Leucine Rich Repeat Ig_2 PF13895.6 KFQ97645.1 - 0.002 18.4 0.0 0.0045 17.3 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain LRR_5 PF13306.6 KFQ97645.1 - 0.0028 17.6 0.0 0.0049 16.8 0.0 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFQ97645.1 - 0.098 12.2 0.1 0.9 9.0 0.3 1.9 1 1 2 3 3 3 0 Leucine-rich repeat LRR_6 PF13516.6 KFQ97645.1 - 0.5 10.6 4.3 4.8 7.5 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich repeat 7tm_1 PF00001.21 KFQ97646.1 - 3.4e-25 88.9 12.6 1.6e-23 83.4 12.6 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFQ97646.1 - 4.1e-05 23.4 9.1 7.3e-05 22.5 9.1 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFQ97646.1 - 1.6 8.1 8.7 5.4 6.3 8.7 2.1 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx MFS_1 PF07690.16 KFQ97647.1 - 2e-29 102.6 33.0 3.6e-26 91.9 26.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 KFQ97647.1 - 0.0008 18.3 0.3 0.0008 18.3 0.3 2.0 2 0 0 2 2 2 1 LacY proton/sugar symporter BT1 PF03092.16 KFQ97647.1 - 0.0025 16.1 0.2 0.0044 15.3 0.2 1.3 1 0 0 1 1 1 1 BT1 family MFS_1_like PF12832.7 KFQ97647.1 - 5.2 5.8 11.2 0.037 12.9 0.6 2.3 1 1 1 2 2 2 0 MFS_1 like family Carn_acyltransf PF00755.20 KFQ97648.1 - 2.1e-195 650.8 0.0 2.4e-195 650.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Globin PF00042.22 KFQ97648.1 - 0.13 12.8 0.1 1 9.9 0.0 2.3 2 0 0 2 2 2 0 Globin E1_dh PF00676.20 KFQ97649.1 - 6.5e-88 294.5 0.1 1.2e-87 293.7 0.1 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 KFQ97649.1 - 3.2e-67 225.6 0.0 5e-67 225.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 KFQ97649.1 - 4e-54 182.5 0.0 7.3e-54 181.6 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KFQ97649.1 - 1.1e-19 69.8 3.5 1.7e-18 65.9 2.0 2.4 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus GGA_N-GAT PF18308.1 KFQ97649.1 - 0.016 14.8 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 GGA N-GAT domain Tim17 PF02466.19 KFQ97650.1 - 7e-20 71.5 2.4 7.8e-20 71.3 2.4 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family C2 PF00168.30 KFQ97651.1 - 2.7e-30 104.7 0.7 9.8e-16 57.9 0.1 2.2 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 KFQ97651.1 - 0.0022 17.6 0.1 0.072 12.6 0.1 2.5 2 0 0 2 2 2 1 CEP76 C2 domain ELFV_dehydrog PF00208.21 KFQ97652.1 - 6.2e-55 186.6 0.0 9e-52 176.2 0.0 2.1 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KFQ97652.1 - 1.1e-41 141.8 0.0 2.2e-41 140.8 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 KFQ97652.1 - 0.056 12.8 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Synuclein PF01387.17 KFQ97653.1 - 2.6e-50 170.1 23.9 2.8e-50 170.0 23.9 1.0 1 0 0 1 1 1 1 Synuclein YtxH PF12732.7 KFQ97653.1 - 0.54 10.8 7.1 2.9 8.5 7.0 1.9 1 1 0 1 1 1 0 YtxH-like protein C1q PF00386.21 KFQ97654.1 - 1.6e-16 60.6 0.2 3e-16 59.8 0.2 1.4 1 0 0 1 1 1 1 C1q domain EMI PF07546.13 KFQ97654.1 - 1.5e-14 54.5 3.1 3.4e-14 53.4 3.1 1.6 1 0 0 1 1 1 1 EMI domain Phlebovirus_NSM PF07246.11 KFQ97654.1 - 0.0087 15.5 0.9 0.0087 15.5 0.9 2.9 3 1 0 4 4 4 1 Phlebovirus nonstructural protein NS-M Pkinase_Tyr PF07714.17 KFQ97655.1 - 7e-38 130.4 0.0 9.6e-38 129.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ97655.1 - 1.1e-37 129.8 0.0 2e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.12 KFQ97655.1 - 6e-16 57.6 0.7 1.2e-15 56.6 0.7 1.6 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.23 KFQ97655.1 - 4.6e-13 50.1 12.1 4.6e-13 50.1 12.1 2.4 2 0 0 2 2 2 1 Activin types I and II receptor domain Pkinase_fungal PF17667.1 KFQ97655.1 - 2.3e-05 23.4 0.0 3.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KFQ97655.1 - 0.028 14.0 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KFQ97655.1 - 0.079 11.9 0.1 0.17 10.8 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 KFQ97655.1 - 0.22 11.4 0.0 0.52 10.2 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family LIM PF00412.22 KFQ97656.1 - 9.2e-38 128.3 31.8 6.3e-14 51.9 4.7 3.2 3 0 0 3 3 3 3 LIM domain DUF4749 PF15936.5 KFQ97656.1 - 6.1e-10 40.1 0.8 6.1e-10 40.1 0.8 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4749) PDZ PF00595.24 KFQ97656.1 - 2.3e-08 34.3 0.3 4.2e-08 33.4 0.3 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFQ97656.1 - 3.3e-05 23.6 0.0 6.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFQ97656.1 - 0.00093 19.5 0.1 0.002 18.4 0.1 1.5 1 0 0 1 1 1 1 PDZ domain 7tm_1 PF00001.21 KFQ97657.1 - 4.4e-53 180.3 13.9 5.2e-53 180.0 13.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ97657.1 - 1.1e-13 51.1 14.9 1.5e-13 50.7 14.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFQ97657.1 - 5.4e-10 39.3 17.7 9e-10 38.6 17.7 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFQ97657.1 - 4.1e-06 26.4 8.5 5.9e-06 25.8 8.5 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFQ97657.1 - 0.058 13.1 16.4 0.0094 15.7 8.4 2.7 2 1 0 2 2 2 0 Olfactory receptor Git3 PF11710.8 KFQ97657.1 - 6.2 6.5 19.1 0.19 11.5 13.0 1.5 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 DUF3742 PF12553.8 KFQ97657.1 - 8.3 6.6 6.0 4.9 7.3 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) WTF PF03303.13 KFQ97657.1 - 9.9 5.8 11.8 0.2 11.4 3.3 2.0 2 0 0 2 2 2 0 WTF protein WAPL PF07814.13 KFQ97658.1 - 3.9e-117 391.1 8.0 6.6e-117 390.4 8.0 1.4 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Wap1 PF16997.5 KFQ97658.1 - 0.00043 19.6 4.4 0.007 15.6 0.1 2.5 2 1 0 2 2 2 2 Wap1 domain ANF_receptor PF01094.28 KFQ97659.1 - 0.0041 16.3 0.1 0.0041 16.3 0.1 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 KFQ97660.1 - 1.7e-43 148.0 0.3 2.9e-43 147.3 0.3 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFQ97660.1 - 4.9e-40 136.3 0.0 8.4e-40 135.5 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFQ97660.1 - 4.1e-26 91.8 0.0 7.2e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 KFQ97660.1 - 3.7e-21 75.6 0.0 6.7e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Receptor family ligand binding region DUF2369 PF10179.9 KFQ97664.1 - 1.1e-35 121.9 1.6 8.9e-33 112.6 0.4 3.4 3 0 0 3 3 3 2 Uncharacterised conserved protein (DUF2369) fn3 PF00041.21 KFQ97664.1 - 3.2e-08 33.8 1.7 0.0029 17.9 0.1 4.7 5 0 0 5 5 5 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFQ97664.1 - 0.00017 22.1 1.0 0.13 12.9 0.2 3.3 2 1 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFQ97664.1 - 4.4 7.7 6.3 4.8 7.5 0.0 4.0 4 1 1 5 5 5 0 Interferon-alpha/beta receptor, fibronectin type III KH_1 PF00013.29 KFQ97665.1 - 2.4e-37 126.5 7.1 1.9e-15 56.4 0.4 5.7 5 0 0 5 5 5 3 KH domain SAM_1 PF00536.30 KFQ97665.1 - 2.7e-14 53.3 0.1 5.6e-14 52.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFQ97665.1 - 4.3e-11 42.8 0.1 1.1e-10 41.4 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) KH_10 PF17905.1 KFQ97665.1 - 7e-09 36.0 0.8 0.0024 18.2 0.2 3.8 3 1 0 3 3 3 2 GLD-3 KH domain 5 SLS PF14611.6 KFQ97665.1 - 0.00025 21.0 1.3 1.8 8.4 0.3 4.5 2 1 1 4 4 4 2 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 KFQ97665.1 - 0.0003 20.6 0.1 0.12 12.2 0.2 2.7 2 0 0 2 2 2 2 KH domain Alanine_zipper PF11839.8 KFQ97665.1 - 0.12 12.8 4.6 0.29 11.5 4.6 1.6 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein IGR PF09597.10 KFQ97665.1 - 0.15 12.2 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 IGR protein motif fn3 PF00041.21 KFQ97666.1 - 2e-07 31.3 0.3 5.2e-07 29.9 0.1 1.8 2 1 0 2 2 2 1 Fibronectin type III domain fn3_4 PF16794.5 KFQ97666.1 - 0.0084 16.0 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 Fibronectin-III type domain GPW_gp25 PF04965.14 KFQ97667.1 - 0.021 14.6 0.3 0.2 11.4 0.0 2.6 3 0 0 3 3 3 0 Gene 25-like lysozyme PKS_DE PF18369.1 KFQ97667.1 - 0.13 12.9 0.0 0.46 11.1 0.0 1.9 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain PilO PF04350.13 KFQ97667.1 - 0.39 10.9 4.8 0.16 12.1 0.8 2.4 2 0 0 2 2 2 0 Pilus assembly protein, PilO PilJ PF13675.6 KFQ97667.1 - 0.53 10.3 2.7 38 4.4 0.1 3.2 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term RhoGAP PF00620.27 KFQ97668.1 - 4.7e-41 140.1 0.2 5.6e-41 139.9 0.2 1.1 1 0 0 1 1 1 1 RhoGAP domain Fanconi_A_N PF15865.5 KFQ97668.1 - 0.016 14.6 0.2 0.021 14.2 0.2 1.1 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus DUF3328 PF11807.8 KFQ97668.1 - 0.14 12.0 0.1 0.21 11.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) MFS_1 PF07690.16 KFQ97669.1 - 3.4e-27 95.3 37.4 6e-16 58.3 15.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2046 PF09755.9 KFQ97670.1 - 5.4e-120 400.2 49.7 6.4e-120 400.0 49.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) ATG16 PF08614.11 KFQ97670.1 - 4 7.6 45.9 0.59 10.3 20.5 2.6 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Death PF00531.22 KFQ97671.1 - 3.7e-21 75.1 0.0 7e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Death domain PYC_OADA PF02436.18 KFQ97671.1 - 0.0077 16.0 0.4 0.019 14.7 0.4 1.7 1 0 0 1 1 1 1 Conserved carboxylase domain ubiquitin PF00240.23 KFQ97671.1 - 0.028 14.2 0.0 0.21 11.4 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin family DUF2533 PF10752.9 KFQ97671.1 - 0.056 13.9 0.7 3.9 8.0 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2533) Ank_2 PF12796.7 KFQ97672.1 - 1.8e-142 464.3 45.8 1.4e-15 57.6 1.0 11.5 2 2 9 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.30 KFQ97672.1 - 6.8e-130 418.4 63.3 2.6e-06 27.6 0.0 23.2 21 1 2 23 23 23 21 Ankyrin repeat Ank_4 PF13637.6 KFQ97672.1 - 2e-126 410.9 55.5 7.5e-11 42.3 0.3 17.1 3 2 16 20 20 20 20 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFQ97672.1 - 2.2e-118 384.7 32.7 2.5e-11 43.6 0.0 15.3 4 4 12 17 17 17 17 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ97672.1 - 1.5e-107 338.4 30.4 0.00013 22.1 0.0 23.6 23 0 0 23 23 23 20 Ankyrin repeat UPA_2 PF17809.1 KFQ97672.1 - 2.1e-52 176.4 0.0 6.6e-52 174.8 0.0 2.0 1 0 0 1 1 1 1 UPA domain ZU5 PF00791.20 KFQ97672.1 - 2.5e-33 114.3 0.9 8.5e-27 93.4 0.0 3.0 2 0 0 2 2 2 2 ZU5 domain DUF1110 PF06533.12 KFQ97672.1 - 4.2 7.3 6.9 0.36 10.8 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1110) BTB PF00651.31 KFQ97673.1 - 6.8e-29 100.3 5.0 3.1e-17 62.8 0.1 3.9 4 0 0 4 4 4 3 BTB/POZ domain Ras PF00071.22 KFQ97673.1 - 8.4e-24 84.0 0.0 1.8e-23 82.9 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFQ97673.1 - 2.6e-10 40.6 0.0 6.7e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase BACK PF07707.15 KFQ97673.1 - 0.81 9.8 4.2 1.8 8.7 0.2 3.1 3 0 0 3 3 3 0 BTB And C-terminal Kelch Tmem26 PF09772.9 KFQ97674.1 - 5e-102 341.1 9.3 5.8e-102 340.9 9.3 1.0 1 0 0 1 1 1 1 Transmembrane protein 26 CLAMP PF14769.6 KFQ97676.1 - 3.4e-13 49.9 0.0 4.9e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 ARID PF01388.21 KFQ97677.1 - 6.6e-17 62.0 0.0 1.6e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Anillin PF08174.11 KFQ97678.1 - 2.9e-47 160.7 0.2 6.6e-47 159.5 0.2 1.6 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.29 KFQ97678.1 - 4e-08 33.7 0.5 1.2e-07 32.2 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KFQ97678.1 - 0.0027 18.1 0.7 0.012 16.0 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain HR1 PF02185.16 KFQ97678.1 - 0.018 15.2 1.3 0.079 13.1 1.3 2.2 1 0 0 1 1 1 0 Hr1 repeat FXMRP1_C_core PF12235.8 KFQ97678.1 - 0.13 13.0 1.0 0.29 11.8 1.0 1.5 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal RBD-FIP PF09457.10 KFQ97679.1 - 0.014 15.3 2.5 0.062 13.2 2.5 2.0 1 1 0 1 1 1 0 FIP domain ERM PF00769.19 KFQ97679.1 - 0.018 14.8 14.5 0.025 14.4 14.5 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Chal_sti_synt_N PF00195.19 KFQ97679.1 - 0.033 13.6 0.1 0.063 12.7 0.1 1.5 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain Pox_G7 PF05503.12 KFQ97679.1 - 0.04 12.8 0.5 0.057 12.4 0.5 1.3 1 1 0 1 1 1 0 Poxvirus G7-like Nipped-B_C PF12830.7 KFQ97679.1 - 0.058 13.3 2.6 0.086 12.8 2.6 1.2 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus PMC2NT PF08066.12 KFQ97679.1 - 0.074 13.8 1.9 3.7 8.3 0.0 3.1 1 1 1 2 2 2 0 PMC2NT (NUC016) domain zf-C2H2_4 PF13894.6 KFQ97679.1 - 0.11 13.4 1.9 0.64 11.0 1.9 2.4 1 0 0 1 1 1 0 C2H2-type zinc finger FapA PF03961.13 KFQ97679.1 - 0.13 10.9 5.5 0.18 10.4 5.5 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A BAF250_C PF12031.8 KFQ97679.1 - 0.15 11.3 2.4 0.15 11.3 1.1 1.6 1 1 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa zf-C2H2 PF00096.26 KFQ97679.1 - 0.18 12.3 2.8 0.43 11.1 2.0 2.2 2 0 0 2 2 1 0 Zinc finger, C2H2 type GrpE PF01025.19 KFQ97679.1 - 0.22 11.2 15.5 5.6 6.6 15.5 2.1 1 1 0 1 1 1 0 GrpE DUF641 PF04859.12 KFQ97679.1 - 0.47 10.8 11.8 0.54 10.6 3.7 2.6 2 1 1 3 3 2 0 Plant protein of unknown function (DUF641) Spc7 PF08317.11 KFQ97679.1 - 0.66 8.8 14.0 0.97 8.3 14.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FUSC PF04632.12 KFQ97679.1 - 0.9 8.0 6.6 1.3 7.5 6.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 KFQ97679.1 - 1.7 8.1 13.1 4.1 6.9 13.1 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit ALS2CR8 PF15299.6 KFQ97679.1 - 1.9 8.4 8.0 2.6 7.9 2.5 2.2 1 1 1 2 2 2 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Fez1 PF06818.15 KFQ97679.1 - 3.3 8.1 16.0 0.71 10.3 5.1 2.4 1 1 1 2 2 2 0 Fez1 CENP-Q PF13094.6 KFQ97679.1 - 8.1 6.6 16.5 1.6 8.9 7.3 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit NRBF2 PF08961.10 KFQ97680.1 - 3.6e-102 340.0 7.7 3.6e-102 340.0 7.7 1.4 2 0 0 2 2 2 1 Nuclear receptor-binding factor 2, autophagy regulator NRBF2_MIT PF17169.4 KFQ97680.1 - 2.2e-45 152.7 11.1 2.2e-45 152.7 11.1 1.7 2 0 0 2 2 2 1 MIT domain of nuclear receptor-binding factor 2 MIT PF04212.18 KFQ97680.1 - 0.00097 19.2 6.1 0.0026 17.8 6.0 1.9 1 1 0 1 1 1 1 MIT (microtubule interacting and transport) domain bZIP_1 PF00170.21 KFQ97680.1 - 0.0013 18.8 0.7 0.0013 18.8 0.7 2.5 2 0 0 2 2 2 1 bZIP transcription factor YabA PF06156.13 KFQ97680.1 - 0.0015 19.2 9.6 0.0025 18.4 0.7 2.2 2 0 0 2 2 2 1 Initiation control protein YabA DivIC PF04977.15 KFQ97680.1 - 0.0016 18.2 2.3 0.0016 18.2 2.3 2.4 2 1 0 2 2 2 1 Septum formation initiator PikAIV_N PF18605.1 KFQ97680.1 - 0.0031 17.1 3.9 0.0067 16.0 3.9 1.6 1 0 0 1 1 1 1 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain HALZ PF02183.18 KFQ97680.1 - 0.0033 17.6 2.1 0.0096 16.1 2.1 1.8 1 0 0 1 1 1 1 Homeobox associated leucine zipper ZapB PF06005.12 KFQ97680.1 - 0.0061 17.0 2.6 0.0061 17.0 2.6 2.5 2 1 1 3 3 2 1 Cell division protein ZapB DUF5101 PF17031.5 KFQ97680.1 - 0.074 13.1 0.7 0.074 13.1 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5101) TPR_7 PF13176.6 KFQ97680.1 - 0.11 12.6 0.1 0.3 11.2 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF724 PF05266.14 KFQ97680.1 - 8 6.2 13.5 0.74 9.6 1.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF724) TB2_DP1_HVA22 PF03134.19 KFQ97681.1 - 3.6e-27 94.1 10.1 6e-27 93.4 10.1 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2306 PF10067.9 KFQ97681.1 - 0.06 13.6 0.8 0.1 12.8 0.8 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) Sugar_tr PF00083.24 KFQ97682.1 - 4e-33 115.0 14.7 5.1e-33 114.6 14.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFQ97682.1 - 2.3e-32 112.3 47.7 1.7e-27 96.3 27.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RVT_1 PF00078.27 KFQ97683.1 - 0.0007 19.2 0.0 0.0013 18.3 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Vinculin PF01044.19 KFQ97685.1 - 2.9e-190 634.9 28.1 2.7e-177 592.0 22.0 2.1 1 1 1 2 2 2 2 Vinculin family AAA_32 PF13654.6 KFQ97685.1 - 0.0026 16.6 8.5 0.37 9.5 0.1 3.1 2 1 1 3 3 3 3 AAA domain LRR_8 PF13855.6 KFQ97686.1 - 8.1e-55 182.4 60.8 2.4e-14 52.8 5.6 5.8 1 1 5 6 6 6 6 Leucine rich repeat LRR_5 PF13306.6 KFQ97686.1 - 2.1e-31 108.5 1.5 7.5e-13 48.6 0.2 3.1 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFQ97686.1 - 4.9e-19 68.1 39.5 5.5e-05 23.5 3.3 6.5 1 1 9 10 10 10 10 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFQ97686.1 - 4.1e-10 39.4 7.6 0.00015 21.3 3.2 3.5 1 1 3 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 KFQ97686.1 - 7.7e-07 28.8 39.2 1.2 9.9 0.6 10.6 10 1 0 10 10 10 2 Leucine Rich Repeat LRR_6 PF13516.6 KFQ97686.1 - 6.9e-06 25.7 30.7 1.1 9.5 0.2 9.6 10 0 0 10 10 10 2 Leucine Rich repeat LRRNT PF01462.18 KFQ97686.1 - 3e-05 23.6 0.6 3e-05 23.6 0.6 2.5 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain EphA2_TM PF14575.6 KFQ97686.1 - 0.12 13.3 0.2 0.33 11.8 0.1 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain LRR_2 PF07723.13 KFQ97686.1 - 6.1 7.7 12.7 10 7.0 0.2 6.3 7 1 1 8 8 8 0 Leucine Rich Repeat Vinculin PF01044.19 KFQ97687.1 - 1.5e-43 149.3 1.5 1.6e-43 149.2 1.5 1.0 1 0 0 1 1 1 1 Vinculin family HTH_57 PF18679.1 KFQ97687.1 - 0.024 15.0 0.4 0.054 13.8 0.2 1.7 2 0 0 2 2 2 0 ThcOx helix turn helix domain PilJ PF13675.6 KFQ97687.1 - 0.034 14.2 1.6 0.76 9.8 0.2 2.2 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term TMEM89 PF15098.6 KFQ97687.1 - 0.089 13.0 0.2 0.18 11.9 0.1 1.4 1 1 0 1 1 1 0 TMEM89 protein family DnaJ PF00226.31 KFQ97688.1 - 4.5e-19 68.3 0.1 9.7e-19 67.3 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Ribosomal_S6 PF01250.17 KFQ97688.1 - 0.14 12.5 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S6 SIR2 PF02146.17 KFQ97689.1 - 3.3e-60 203.0 0.0 5.8e-60 202.2 0.0 1.4 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KFQ97689.1 - 0.00088 19.0 0.0 0.38 10.5 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 KFQ97689.1 - 0.0052 16.6 0.2 0.01 15.6 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) HLH PF00010.26 KFQ97690.1 - 1.2e-18 66.8 0.1 1.7e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DERM PF14704.6 KFQ97690.1 - 0.036 14.5 0.8 0.39 11.2 0.3 2.1 1 1 1 2 2 2 0 Dermatopontin DUF1295 PF06966.12 KFQ97690.1 - 0.099 12.1 0.1 0.13 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) PhzC-PhzF PF02567.16 KFQ97691.1 - 2.1e-59 201.3 0.0 2.6e-59 201.0 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein DAP_epimerase PF01678.19 KFQ97691.1 - 0.086 13.0 0.0 6 7.1 0.0 2.4 2 0 0 2 2 2 0 Diaminopimelate epimerase RRM_1 PF00076.22 KFQ97692.1 - 1.1e-21 76.4 0.0 1.1e-10 41.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RUN PF02759.19 KFQ97693.1 - 3.9e-29 101.3 0.2 7.8e-29 100.4 0.0 1.6 2 0 0 2 2 2 1 RUN domain Trimer_CC PF08954.11 KFQ97693.1 - 0.0066 16.0 0.3 0.23 11.0 0.0 2.5 2 0 0 2 2 2 1 Trimerisation motif Shugoshin_N PF07558.11 KFQ97693.1 - 0.06 13.2 0.9 0.2 11.5 0.9 1.9 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region ATG16 PF08614.11 KFQ97693.1 - 0.21 11.8 19.9 0.29 11.3 19.9 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) CASP_C PF08172.12 KFQ97693.1 - 0.37 10.1 13.3 0.77 9.0 4.2 2.7 2 1 1 3 3 3 0 CASP C terminal COG2 PF06148.11 KFQ97693.1 - 0.37 10.9 17.0 0.054 13.6 9.3 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Nnf1 PF03980.14 KFQ97693.1 - 0.88 10.0 15.2 0.98 9.8 0.1 3.3 2 1 1 3 3 3 0 Nnf1 SlyX PF04102.12 KFQ97693.1 - 0.93 10.2 14.0 2.9 8.6 4.9 3.1 2 2 0 2 2 2 0 SlyX DUF948 PF06103.11 KFQ97693.1 - 1.3 9.4 5.5 24 5.2 0.4 3.2 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 KFQ97693.1 - 2.3 7.0 23.7 2.7 6.8 11.7 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Mod_r PF07200.13 KFQ97693.1 - 4.3 7.4 20.8 2.3 8.3 9.8 2.4 1 1 1 2 2 1 0 Modifier of rudimentary (Mod(r)) protein Dna2 PF08696.11 KFQ97694.1 - 2e-62 210.6 0.1 4.5e-62 209.5 0.1 1.6 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 KFQ97694.1 - 2.2e-47 161.3 5.1 1.6e-31 109.5 0.2 2.9 2 1 1 3 3 3 2 AAA domain AAA_11 PF13086.6 KFQ97694.1 - 2.5e-32 112.7 0.4 4.1e-16 59.5 0.2 2.5 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 KFQ97694.1 - 7.9e-15 55.1 0.0 2.4e-14 53.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFQ97694.1 - 2.1e-11 44.4 0.0 7.5e-11 42.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain PDDEXK_1 PF12705.7 KFQ97694.1 - 6.3e-09 36.1 0.0 9.4e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.18 KFQ97694.1 - 1.9e-07 31.0 0.7 0.17 11.6 0.0 3.6 2 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Cas_Cas4 PF01930.17 KFQ97694.1 - 5.5e-05 23.3 7.2 0.03 14.4 2.4 3.6 2 1 0 2 2 2 2 Domain of unknown function DUF83 SRP54 PF00448.22 KFQ97694.1 - 0.0014 18.3 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain cobW PF02492.19 KFQ97694.1 - 0.0033 17.0 0.0 0.0071 16.0 0.0 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain UvrD_C_2 PF13538.6 KFQ97694.1 - 0.0052 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KFQ97694.1 - 0.0071 15.9 2.8 0.017 14.7 0.0 2.5 2 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain AAA_25 PF13481.6 KFQ97694.1 - 0.0097 15.5 0.0 0.025 14.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 KFQ97694.1 - 0.013 14.9 0.1 0.059 12.8 0.1 2.2 1 1 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 KFQ97694.1 - 0.018 14.6 0.2 0.039 13.5 0.2 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region CbiA PF01656.23 KFQ97694.1 - 0.019 15.0 2.2 0.066 13.3 2.2 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF853 PF05872.12 KFQ97694.1 - 0.019 13.6 0.1 0.029 13.0 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA PF00004.29 KFQ97694.1 - 0.028 14.8 0.1 0.077 13.4 0.1 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 KFQ97694.1 - 0.056 13.4 0.6 0.52 10.3 0.4 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KFQ97694.1 - 0.057 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Helicase_RecD PF05127.14 KFQ97694.1 - 0.07 13.0 0.0 0.26 11.1 0.0 2.0 2 1 0 2 2 1 0 Helicase AAA_29 PF13555.6 KFQ97694.1 - 0.072 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KFQ97694.1 - 0.076 13.5 1.6 0.12 12.9 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 KFQ97694.1 - 0.12 12.9 0.1 0.44 11.1 0.1 2.0 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 KFQ97694.1 - 0.12 12.2 0.3 0.32 10.9 0.1 1.8 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B Mito_carr PF00153.27 KFQ97695.1 - 3.9e-67 222.2 6.9 7.1e-23 80.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFQ97695.1 - 0.00016 20.9 1.1 0.037 13.2 0.3 2.8 2 2 0 2 2 2 2 Gammaproteobacterial serine protease Tet_JBP PF12851.7 KFQ97696.1 - 5.2e-74 249.6 0.0 5.2e-74 249.6 0.0 2.7 2 1 1 3 3 3 1 Oxygenase domain of the 2OGFeDO superfamily zf-CXXC PF02008.20 KFQ97696.1 - 7.3e-05 22.7 28.8 7.3e-05 22.7 28.8 2.4 2 0 0 2 2 2 1 CXXC zinc finger domain DBC1 PF14443.6 KFQ97697.1 - 8.4e-53 177.6 0.0 4.8e-52 175.2 0.0 2.4 1 0 0 1 1 1 1 DBC1 S1-like PF14444.6 KFQ97697.1 - 2.7e-33 113.7 0.9 4.9e-33 112.9 0.9 1.4 1 0 0 1 1 1 1 S1-like SAP PF02037.27 KFQ97697.1 - 1.7e-08 34.0 5.8 2.7e-08 33.4 2.0 2.5 2 0 0 2 2 2 1 SAP domain Tautomerase_2 PF14552.6 KFQ97697.1 - 0.028 14.5 0.1 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 Tautomerase enzyme CorA PF01544.18 KFQ97697.1 - 0.21 10.9 4.9 0.48 9.7 4.9 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Stork_head PF10264.9 KFQ97698.1 - 1.6e-31 108.3 0.1 4.7e-31 106.8 0.1 1.9 1 0 0 1 1 1 1 Winged helix Storkhead-box1 domain GUCT PF08152.12 KFQ97699.1 - 1.2e-31 108.9 0.0 3.9e-31 107.2 0.0 1.9 2 0 0 2 2 2 1 GUCT (NUC152) domain Helicase_C PF00271.31 KFQ97699.1 - 4.3e-25 88.2 0.0 9.8e-25 87.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KFQ97699.1 - 0.0067 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase KBP_C PF12309.8 KFQ97700.1 - 1.1e-127 426.4 11.4 1.1e-127 426.4 11.4 2.3 2 0 0 2 2 2 1 KIF-1 binding protein C terminal AbiJ_NTD5 PF18865.1 KFQ97700.1 - 0.01 15.6 0.0 0.042 13.7 0.0 2.0 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 TPR_12 PF13424.6 KFQ97700.1 - 0.017 15.4 12.4 1.4 9.2 0.7 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ97700.1 - 0.056 13.3 0.5 0.056 13.3 0.5 4.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ97700.1 - 0.062 13.3 9.6 2.4 8.4 0.6 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ97700.1 - 2.7 8.0 6.7 1.9 8.5 0.3 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Serglycin PF04360.12 KFQ97701.1 - 2.6e-26 92.4 0.0 2.6e-26 92.3 0.0 1.0 1 0 0 1 1 1 1 Serglycin Vps26 PF03643.15 KFQ97702.1 - 9.5e-134 444.6 5.8 1.1e-133 444.4 5.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.22 KFQ97702.1 - 0.0012 19.3 0.2 0.032 14.7 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KFQ97702.1 - 0.015 15.3 0.4 0.5 10.4 0.0 3.0 2 1 1 3 3 3 0 Arrestin (or S-antigen), N-terminal domain Suv3_N PF18114.1 KFQ97703.1 - 2.9e-35 120.9 0.3 6.2e-35 119.8 0.3 1.6 1 0 0 1 1 1 1 Suv3 helical N-terminal domain Suv3_C_1 PF18147.1 KFQ97703.1 - 5.7e-16 58.1 0.2 1.1e-15 57.2 0.2 1.5 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 SUV3_C PF12513.8 KFQ97703.1 - 4.2e-15 55.4 0.0 1e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 KFQ97703.1 - 2.5e-11 43.9 0.0 5.7e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Hexokinase_2 PF03727.16 KFQ97704.1 - 2.2e-169 560.9 0.9 4.8e-88 294.6 0.1 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.21 KFQ97704.1 - 1e-134 446.6 0.0 2.4e-70 236.5 0.0 2.3 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.21 KFQ97705.1 - 2.6e-143 474.7 0.2 1.5e-72 243.7 0.1 2.3 2 0 0 2 2 2 2 Hexokinase Hexokinase_2 PF03727.16 KFQ97705.1 - 8.4e-143 473.9 0.4 1.3e-81 273.5 0.0 3.2 3 0 0 3 3 3 3 Hexokinase CSD PF00313.22 KFQ97705.1 - 0.082 12.8 0.0 4.6 7.2 0.0 2.7 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain 7tm_1 PF00001.21 KFQ97706.1 - 1.1e-57 195.3 21.3 1.4e-57 195.0 21.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ97706.1 - 1.2e-09 38.0 24.1 1.5e-09 37.6 24.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFQ97706.1 - 0.0048 16.7 23.0 0.01 15.6 23.0 1.7 1 1 0 1 1 1 1 Olfactory receptor Herpes_US9 PF06072.11 KFQ97706.1 - 0.1 12.5 3.1 0.49 10.3 1.0 2.9 1 1 1 2 2 2 0 Alphaherpesvirus tegument protein US9 Tetraspanin PF00335.20 KFQ97707.1 - 4.2e-49 167.3 9.4 5e-49 167.1 9.4 1.1 1 0 0 1 1 1 1 Tetraspanin family Macro PF01661.21 KFQ97708.1 - 6.9e-27 93.8 0.1 1.3e-26 93.0 0.1 1.4 1 0 0 1 1 1 1 Macro domain Histone_H2A_C PF16211.5 KFQ97708.1 - 1.6e-16 59.7 0.6 1.6e-16 59.7 0.6 2.4 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.24 KFQ97708.1 - 3.2e-13 50.2 6.5 4.5e-12 46.5 0.0 2.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFQ97708.1 - 0.0066 16.7 0.0 0.017 15.4 0.0 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone AAR2 PF05282.11 KFQ97708.1 - 0.061 12.7 1.3 0.11 11.9 0.9 1.5 2 0 0 2 2 2 0 AAR2 protein Clp_N PF02861.20 KFQ97708.1 - 0.068 13.3 0.2 0.49 10.6 0.0 2.5 3 0 0 3 3 3 0 Clp amino terminal domain, pathogenicity island component DUF1764 PF08576.10 KFQ97708.1 - 0.13 13.2 5.5 0.32 11.9 5.5 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Pyr_redox_2 PF07992.14 KFQ97709.1 - 7.7e-43 146.8 1.8 9e-43 146.6 1.8 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFQ97709.1 - 3e-12 46.9 3.4 5.6e-09 36.4 0.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFQ97709.1 - 3.5e-09 36.3 0.6 2.4e-08 33.6 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFQ97709.1 - 1.8e-08 33.9 1.8 5.4e-06 25.8 0.0 2.7 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KFQ97709.1 - 1.5e-07 31.5 3.1 0.073 13.1 0.1 4.1 4 0 0 4 4 4 2 FAD-NAD(P)-binding GIDA PF01134.22 KFQ97709.1 - 5.8e-05 22.3 12.2 0.87 8.6 0.7 4.2 3 1 1 4 4 4 3 Glucose inhibited division protein A DAO PF01266.24 KFQ97709.1 - 0.00015 21.4 8.9 0.088 12.4 0.0 3.7 3 1 0 4 4 4 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KFQ97709.1 - 0.00028 20.2 2.6 0.027 13.8 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KFQ97709.1 - 0.00071 18.4 3.9 0.25 10.0 0.2 3.6 4 0 0 4 4 4 2 HI0933-like protein NAD_binding_8 PF13450.6 KFQ97709.1 - 0.0012 19.0 1.8 0.82 9.9 0.1 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KFQ97709.1 - 0.0019 17.3 3.3 0.061 12.4 0.2 3.2 4 0 0 4 4 4 1 Lycopene cyclase protein Trp_halogenase PF04820.14 KFQ97709.1 - 0.0031 16.5 5.3 1.1 8.1 0.3 3.2 3 0 0 3 3 3 2 Tryptophan halogenase Peptidase_S28 PF05577.12 KFQ97709.1 - 0.016 14.0 0.2 0.76 8.5 0.0 2.1 2 0 0 2 2 2 0 Serine carboxypeptidase S28 FAD_binding_3 PF01494.19 KFQ97709.1 - 0.019 14.2 1.0 0.21 10.8 0.2 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 KFQ97709.1 - 0.021 15.3 1.8 0.084 13.3 0.4 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding Thi4 PF01946.17 KFQ97709.1 - 0.042 13.1 3.7 0.11 11.7 0.7 2.6 2 1 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 KFQ97709.1 - 0.05 13.9 0.2 12 6.2 0.1 2.7 2 0 0 2 2 2 0 TrkA-N domain DUF4147 PF13660.6 KFQ97709.1 - 0.058 12.9 1.7 0.073 12.6 0.4 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4147) FAD_binding_2 PF00890.24 KFQ97709.1 - 0.14 11.2 6.1 3.1 6.8 0.4 2.8 3 1 0 3 3 3 0 FAD binding domain StbA PF06406.11 KFQ97709.1 - 0.61 9.3 3.6 1.1 8.5 0.1 2.7 4 0 0 4 4 4 0 StbA protein Sulfotransfer_1 PF00685.27 KFQ97711.1 - 6.3e-49 166.9 0.0 7.7e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFQ97711.1 - 1.2e-09 38.9 0.1 4.7e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 Sulfotransferase family SapB_2 PF03489.17 KFQ97712.1 - 4.4e-43 145.1 47.8 2.1e-12 46.9 3.0 6.1 7 0 0 7 7 7 4 Saposin-like type B, region 2 SapB_1 PF05184.15 KFQ97712.1 - 8.7e-43 143.9 25.6 8.7e-14 51.2 1.2 5.7 5 0 0 5 5 5 4 Saposin-like type B, region 1 SapA PF02199.15 KFQ97712.1 - 3.2e-16 59.3 9.5 3.2e-16 59.3 9.5 3.9 4 0 0 4 4 4 2 Saposin A-type domain TLE_N PF03920.15 KFQ97712.1 - 0.1 12.7 5.2 0.84 9.7 0.1 3.2 3 1 1 4 4 4 0 Groucho/TLE N-terminal Q-rich domain DUF4359 PF14271.6 KFQ97712.1 - 0.11 13.3 8.5 6.3 7.6 0.0 4.8 3 2 1 5 5 5 0 Domain of unknown function (DUF4359) DUF4451 PF14616.6 KFQ97712.1 - 1.9 8.7 10.4 10 6.4 0.2 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4451) SapB_1 PF05184.15 KFQ97713.1 - 7e-22 77.1 11.2 1.4e-12 47.3 2.8 2.6 2 0 0 2 2 2 2 Saposin-like type B, region 1 SapB_2 PF03489.17 KFQ97713.1 - 7.4e-16 58.0 4.4 1.6e-10 40.9 1.2 2.9 2 0 0 2 2 2 2 Saposin-like type B, region 2 Helicase_C_3 PF13625.6 KFQ97713.1 - 0.027 14.6 0.0 0.05 13.8 0.0 1.4 1 0 0 1 1 1 0 Helicase conserved C-terminal domain SFTA2 PF15210.6 KFQ97713.1 - 0.075 13.0 0.5 3 7.9 0.0 2.5 2 0 0 2 2 2 0 Surfactant-associated protein 2 Cadherin PF00028.17 KFQ97714.1 - 0 1449.0 43.4 1.3e-19 70.4 0.3 27.3 27 0 0 27 27 27 27 Cadherin domain Cadherin_2 PF08266.12 KFQ97714.1 - 1.4e-25 88.9 0.0 0.49 10.3 0.0 16.0 19 0 0 19 19 19 6 Cadherin-like Cadherin_3 PF16184.5 KFQ97714.1 - 8.4e-23 80.5 37.9 0.0022 17.9 0.1 19.2 22 0 0 22 22 22 9 Cadherin-like RET_CLD1 PF17756.1 KFQ97714.1 - 4.5e-12 46.3 0.0 0.54 10.5 0.0 9.7 11 0 0 11 11 11 2 RET Cadherin like domain 1 SusE PF14292.6 KFQ97714.1 - 0.62 10.3 11.7 3.5 7.9 0.0 6.4 6 0 0 6 6 6 0 SusE outer membrane protein V-set PF07686.17 KFQ97715.1 - 3.9e-06 27.0 0.3 6.4e-05 23.1 0.3 2.2 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFQ97715.1 - 2.1e-05 24.6 0.5 0.0005 20.2 0.5 2.2 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFQ97715.1 - 0.00014 22.1 0.2 0.83 10.0 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 KFQ97715.1 - 0.00018 22.1 0.1 0.0021 18.6 0.1 2.4 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ97715.1 - 0.012 15.7 0.0 3 8.0 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin I-set domain V-set_CD47 PF08204.11 KFQ97715.1 - 0.19 11.7 0.1 1.7 8.7 0.0 2.0 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain DUF5527 PF17665.1 KFQ97716.1 - 7.5e-77 255.6 2.2 8.3e-77 255.4 2.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5527) Oxidored_q2 PF00420.24 KFQ97716.1 - 0.081 12.6 0.6 0.11 12.1 0.6 1.1 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Nucleoside_tran PF01733.18 KFQ97718.1 - 8.4e-71 238.9 8.7 8.4e-71 238.9 8.7 2.0 1 1 1 2 2 2 1 Nucleoside transporter UPA PF17217.3 KFQ97719.1 - 4.8e-72 240.4 0.0 8.3e-72 239.6 0.0 1.4 1 0 0 1 1 1 1 UPA domain ZU5 PF00791.20 KFQ97719.1 - 4.8e-31 107.0 0.0 1e-30 105.9 0.0 1.6 1 0 0 1 1 1 1 ZU5 domain Death PF00531.22 KFQ97719.1 - 1.8e-14 53.6 0.2 3.5e-14 52.7 0.2 1.5 1 0 0 1 1 1 1 Death domain Ig_3 PF13927.6 KFQ97719.1 - 1.8e-11 44.5 0.0 1.7e-07 31.7 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain TSP_1 PF00090.19 KFQ97719.1 - 8e-11 42.0 27.5 1.9e-07 31.1 9.9 2.9 2 0 0 2 2 2 2 Thrombospondin type 1 domain I-set PF07679.16 KFQ97719.1 - 1.9e-10 40.7 0.0 4.4e-09 36.3 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 KFQ97719.1 - 1.4e-06 28.3 0.0 4.1e-05 23.7 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFQ97719.1 - 9.7e-06 25.8 0.0 0.00041 20.6 0.0 2.9 2 0 0 2 2 2 1 Immunoglobulin domain Pterin_4a PF01329.19 KFQ97720.1 - 6.8e-32 109.5 0.0 7.6e-32 109.3 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Pyridoxal_deC PF00282.19 KFQ97721.1 - 5.5e-18 64.8 0.0 8.9e-18 64.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KFQ97721.1 - 6e-14 51.8 0.0 3.8e-13 49.1 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFQ97721.1 - 0.017 14.4 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase ApoLp-III PF07464.11 KFQ97721.1 - 0.052 13.6 0.1 1.3 9.1 0.0 2.7 3 1 1 4 4 4 0 Apolipophorin-III precursor (apoLp-III) SepSecS PF05889.13 KFQ97721.1 - 0.12 11.0 0.0 0.33 9.6 0.0 1.7 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Vitellogenin_N PF01347.22 KFQ97722.1 - 5.1e-15 54.9 0.1 6.8e-15 54.5 0.1 1.1 1 0 0 1 1 1 1 Lipoprotein amino terminal region DUF1943 PF09172.11 KFQ97722.1 - 5.8e-05 22.5 0.3 0.00095 18.5 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1943) Apolipo_F PF15148.6 KFQ97722.1 - 0.074 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein F START PF01852.19 KFQ97723.1 - 1.2e-26 93.4 0.0 2.6e-26 92.3 0.0 1.5 1 1 0 1 1 1 1 START domain Polyketide_cyc PF03364.20 KFQ97723.1 - 0.014 15.6 0.0 0.035 14.3 0.0 1.6 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Pep_M12B_propep PF01562.19 KFQ97724.1 - 3e-30 105.3 0.0 6e-30 104.3 0.0 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_spacer1 PF05986.14 KFQ97724.1 - 9.1e-27 93.4 0.1 1.5e-26 92.7 0.1 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.19 KFQ97724.1 - 5.3e-22 77.8 60.3 1.4e-11 44.4 5.9 6.1 6 0 0 6 6 5 4 Thrombospondin type 1 domain Reprolysin PF01421.19 KFQ97724.1 - 2.6e-20 73.2 0.0 5.3e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 KFQ97724.1 - 2.7e-20 72.6 6.1 2.7e-20 72.6 6.1 5.0 3 2 1 4 4 4 2 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 KFQ97724.1 - 4.3e-16 59.6 0.6 9.5e-16 58.5 0.6 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFQ97724.1 - 1.9e-10 41.3 0.2 3.5e-10 40.5 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFQ97724.1 - 8.4e-09 35.6 0.5 1.7e-08 34.6 0.5 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFQ97724.1 - 8.1e-07 28.9 0.2 2.1e-06 27.5 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like PLAC PF08686.11 KFQ97724.1 - 0.0017 19.1 5.8 0.0017 19.1 5.8 3.0 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain Peptidase_M10 PF00413.24 KFQ97724.1 - 0.0028 17.5 0.1 0.0051 16.7 0.1 1.5 1 0 0 1 1 1 1 Matrixin zf-RING_5 PF14634.6 KFQ97724.1 - 0.011 15.7 2.6 0.092 12.7 2.6 2.8 1 0 0 1 1 1 0 zinc-RING finger domain DUF4953 PF16313.5 KFQ97724.1 - 0.096 11.9 0.2 0.15 11.2 0.2 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M7 PF02031.16 KFQ97724.1 - 0.2 11.8 0.1 0.2 11.8 0.1 1.9 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family PTPlike_phytase PF14566.6 KFQ97725.1 - 2.8e-84 280.9 0.0 7.3e-42 143.1 0.0 2.6 2 0 0 2 2 2 2 Inositol hexakisphosphate Y_phosphatase PF00102.27 KFQ97725.1 - 0.0082 15.7 0.0 0.31 10.6 0.0 2.3 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFQ97725.1 - 0.0096 15.9 0.0 0.1 12.6 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family HTH_48 PF17906.1 KFQ97725.1 - 0.036 14.2 0.4 0.17 12.0 0.1 2.3 2 0 0 2 2 2 0 HTH domain in Mos1 transposase eIF_4EBP PF05456.11 KFQ97726.1 - 2.3e-23 82.3 0.0 2.5e-23 82.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) LRR_8 PF13855.6 KFQ97727.1 - 8.8e-17 60.6 2.6 8.2e-08 31.9 3.4 2.7 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KFQ97727.1 - 1.1e-12 47.9 3.2 0.00054 20.3 0.0 3.8 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFQ97727.1 - 4.2e-08 32.7 6.6 3.4 8.6 0.1 6.0 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.6 KFQ97727.1 - 7e-06 25.7 5.6 0.54 10.4 0.0 5.4 6 0 0 6 6 6 2 Leucine Rich repeat LRR_9 PF14580.6 KFQ97727.1 - 0.00018 21.1 0.7 0.0011 18.5 0.2 1.8 1 1 0 1 1 1 1 Leucine-rich repeat 7tm_1 PF00001.21 KFQ97728.1 - 4.7e-54 183.5 16.7 4.7e-54 183.5 16.7 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ97728.1 - 3e-10 39.9 13.4 5.2e-10 39.1 13.4 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFQ97728.1 - 7.4e-06 25.9 14.2 1.3e-05 25.1 14.2 1.4 1 1 0 1 1 1 1 Olfactory receptor PRIMA1 PF16101.5 KFQ97728.1 - 2 8.5 4.8 2.7 8.0 0.8 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Pyrophosphatase PF00719.19 KFQ97729.1 - 1.3e-61 207.1 0.8 1.6e-61 206.8 0.8 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF2125 PF09898.9 KFQ97729.1 - 0.21 11.2 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2125) Arf PF00025.21 KFQ97730.1 - 5.9e-63 211.5 0.0 6.7e-63 211.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFQ97730.1 - 4.2e-09 36.1 0.0 5.3e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFQ97730.1 - 1.4e-08 34.3 0.1 2.8e-06 26.7 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KFQ97730.1 - 5.8e-08 33.0 0.0 1.2e-07 32.0 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFQ97730.1 - 9.5e-07 28.6 0.0 1.1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KFQ97730.1 - 5.2e-06 26.5 0.0 7.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFQ97730.1 - 0.00034 20.2 0.0 0.0032 17.0 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Metalloenzyme PF01676.18 KFQ97730.1 - 0.015 14.7 0.0 0.13 11.6 0.0 1.9 1 1 1 2 2 2 0 Metalloenzyme superfamily Gtr1_RagA PF04670.12 KFQ97730.1 - 0.02 14.2 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Kazal_2 PF07648.15 KFQ97731.1 - 5.1e-11 42.5 9.6 1.4e-10 41.1 9.6 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain SPARC_Ca_bdg PF10591.9 KFQ97731.1 - 6.6e-05 23.2 0.0 0.00013 22.2 0.0 1.6 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_1 PF00050.21 KFQ97731.1 - 0.00059 19.8 7.6 0.0007 19.5 5.2 2.3 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Thyroglobulin_1 PF00086.18 KFQ97731.1 - 0.00076 19.1 0.1 0.00076 19.1 0.1 2.0 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat AKAP7_NLS PF10469.9 KFQ97732.1 - 1.6e-58 198.0 0.2 1.9e-58 197.8 0.2 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain KH_1 PF00013.29 KFQ97732.1 - 2e-10 40.3 0.9 2e-10 40.3 0.9 1.7 2 0 0 2 2 2 1 KH domain KH_2 PF07650.17 KFQ97732.1 - 0.023 14.5 0.1 0.052 13.4 0.1 1.6 1 0 0 1 1 1 0 KH domain HVSL PF09749.9 KFQ97732.1 - 0.05 13.1 0.1 0.07 12.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein ANAPC16 PF17256.2 KFQ97733.1 - 6.3e-57 189.9 0.1 7.5e-57 189.7 0.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 16 DUF2110 PF09883.9 KFQ97733.1 - 0.09 12.4 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) RTP801_C PF07809.11 KFQ97734.1 - 1.3e-39 134.7 0.0 1.6e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 RTP801 C-terminal region DUF1977 PF09320.11 KFQ97735.1 - 2.8e-28 98.3 0.2 4.9e-28 97.5 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 KFQ97735.1 - 3.8e-27 94.2 0.9 5.9e-27 93.6 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 KFQ97735.1 - 0.012 15.5 0.0 0.26 11.2 0.0 2.3 2 0 0 2 2 2 0 A repeated domain in UCH-protein MCU PF04678.13 KFQ97736.1 - 5.4e-73 244.8 1.1 6.7e-73 244.5 1.1 1.1 1 0 0 1 1 1 1 Mitochondrial calcium uniporter DUF2960 PF11173.8 KFQ97736.1 - 0.02 15.3 0.0 0.064 13.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2960) SPX PF03105.19 KFQ97736.1 - 0.35 10.8 1.3 0.36 10.7 0.2 1.6 2 0 0 2 2 2 0 SPX domain TPR_MLP1_2 PF07926.12 KFQ97736.1 - 1.9 8.6 8.6 0.68 10.0 4.0 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Zona_pellucida PF00100.23 KFQ97737.1 - 4.1e-48 164.4 0.2 2e-47 162.2 0.1 2.0 2 0 0 2 2 2 1 Zona pellucida-like domain FXa_inhibition PF14670.6 KFQ97737.1 - 2.5e-17 62.9 29.1 2.7e-10 40.4 10.6 4.6 6 0 0 6 6 6 3 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFQ97737.1 - 3.5e-08 33.2 16.8 0.0024 17.7 0.4 4.2 3 0 0 3 3 3 3 Complement Clr-like EGF-like PLA2G12 PF06951.11 KFQ97738.1 - 6.6e-89 296.6 9.4 7.9e-89 296.4 9.4 1.0 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) P4Ha_N PF08336.11 KFQ97739.1 - 1.3e-40 138.6 1.2 1.5e-40 138.4 0.1 1.7 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 KFQ97739.1 - 4.8e-16 59.4 0.0 1e-15 58.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KFQ97739.1 - 1.2e-08 35.4 0.0 2.3e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fis1_TPR_C PF14853.6 KFQ97739.1 - 0.0013 18.7 0.5 0.013 15.6 0.5 2.5 1 1 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 KFQ97739.1 - 0.049 13.8 0.8 0.35 11.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ97739.1 - 0.072 13.9 0.2 0.3 12.0 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat YfiO PF13525.6 KFQ97739.1 - 0.095 12.4 2.0 0.22 11.2 2.0 1.6 1 0 0 1 1 1 0 Outer membrane lipoprotein SGT1 PF07093.11 KFQ97740.1 - 6.1e-199 662.3 1.1 6.9e-199 662.1 1.1 1.0 1 0 0 1 1 1 1 SGT1 protein zf-RING_14 PF17978.1 KFQ97740.1 - 0.091 13.2 0.1 0.2 12.1 0.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF3719 PF12516.8 KFQ97741.1 - 2.9e-20 71.7 0.1 9.9e-20 70.0 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3719) FAM220 PF15487.6 KFQ97741.1 - 2.3 7.8 5.2 1 9.0 0.5 2.2 2 0 0 2 2 2 0 FAM220 family DnaJ PF00226.31 KFQ97742.1 - 0.019 15.1 0.5 0.077 13.1 0.0 2.2 2 0 0 2 2 2 0 DnaJ domain DUF1266 PF06889.11 KFQ97742.1 - 0.18 11.8 3.6 0.22 11.5 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1266) Golgin_A5 PF09787.9 KFQ97742.1 - 0.25 10.8 4.8 0.12 11.9 2.2 1.6 1 1 0 1 1 1 0 Golgin subfamily A member 5 HMG_box PF00505.19 KFQ97743.1 - 3.6e-29 101.0 22.9 7.1e-21 74.4 5.9 3.5 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KFQ97743.1 - 1.1e-17 64.4 20.1 3e-09 37.3 0.9 3.2 3 1 0 3 3 3 2 HMG-box domain YABBY PF04690.13 KFQ97743.1 - 0.014 16.0 0.4 0.014 16.0 0.4 3.0 1 1 2 3 3 3 0 YABBY protein DUF1612 PF07756.12 KFQ97743.1 - 0.087 13.1 4.1 1 9.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1612) Protamine_like PF06382.11 KFQ97743.1 - 0.52 10.5 14.4 0.61 10.3 3.8 3.2 1 1 2 3 3 3 0 Protamine and protamine like DUF4055 PF13264.6 KFQ97743.1 - 9 6.4 7.7 1.8 8.7 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) UQ_con PF00179.26 KFQ97744.1 - 7.8e-50 168.2 0.0 8.6e-50 168.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFQ97744.1 - 0.0016 18.8 0.0 0.0018 18.6 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KFQ97744.1 - 0.0075 16.0 0.0 0.009 15.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KFQ97744.1 - 0.076 12.9 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain zf-CDGSH PF09360.10 KFQ97745.1 - 6.7e-10 39.0 0.3 1.2e-09 38.3 0.3 1.5 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type MitoNEET_N PF10660.9 KFQ97745.1 - 2.4e-08 33.9 0.2 3.1e-08 33.5 0.2 1.2 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus CHDNT PF08073.12 KFQ97745.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 CHDNT (NUC034) domain IPK PF03770.16 KFQ97746.1 - 1.5e-68 230.5 0.1 2.6e-68 229.8 0.1 1.4 1 1 0 1 1 1 1 Inositol polyphosphate kinase TMP-TENI PF02581.17 KFQ97746.1 - 0.16 11.3 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase Cadherin PF00028.17 KFQ97747.1 - 3.5e-124 405.6 22.9 2.2e-17 63.3 0.1 10.7 10 0 0 10 10 10 10 Cadherin domain ECD PF18432.1 KFQ97747.1 - 2.6e-52 175.5 1.5 1.9e-50 169.4 1.4 3.6 3 0 0 3 3 3 1 Extracellular Cadherin domain Cadherin_2 PF08266.12 KFQ97747.1 - 2.4e-08 33.7 0.0 0.37 10.7 0.0 5.3 5 0 0 5 5 5 3 Cadherin-like RET_CLD1 PF17756.1 KFQ97747.1 - 5.2e-08 33.2 0.0 0.21 11.9 0.0 4.8 4 0 0 4 4 4 2 RET Cadherin like domain 1 DUF3149 PF11346.8 KFQ97747.1 - 0.026 14.1 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Prokineticin PF06607.11 KFQ97749.1 - 0.00035 20.8 6.2 0.00051 20.3 6.2 1.3 1 0 0 1 1 1 1 Prokineticin MIT_LIKE_ACTX PF17556.2 KFQ97749.1 - 0.0022 18.5 6.3 0.0029 18.1 6.3 1.3 1 0 0 1 1 1 1 MIT-like atracotoxin family Dickkopf_N PF04706.12 KFQ97749.1 - 0.0041 17.6 4.0 0.0041 17.6 4.0 2.2 1 1 1 2 2 2 1 Dickkopf N-terminal cysteine-rich region Pkinase PF00069.25 KFQ97750.1 - 2.3e-71 240.3 0.0 3.2e-71 239.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ97750.1 - 6.6e-36 123.9 0.0 9.9e-36 123.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 KFQ97750.1 - 4.9e-35 119.5 0.1 3.8e-20 71.7 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Kinase-like PF14531.6 KFQ97750.1 - 2.7e-05 23.6 0.0 4.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFQ97750.1 - 0.012 15.6 0.0 0.22 11.4 0.0 2.3 2 1 0 3 3 3 0 Phosphotransferase enzyme family Pkinase_C PF00433.24 KFQ97750.1 - 0.03 15.0 3.7 0.073 13.8 3.7 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain Beach PF02138.18 KFQ97751.1 - 0.074 12.4 0.0 0.084 12.2 0.0 1.1 1 0 0 1 1 1 0 Beige/BEACH domain RRM_1 PF00076.22 KFQ97752.1 - 1.6e-40 136.8 1.6 5.9e-17 61.3 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DND1_DSRM PF14709.7 KFQ97752.1 - 1.2e-24 86.4 0.1 2.5e-24 85.3 0.1 1.6 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 PHM7_cyt PF14703.6 KFQ97752.1 - 4.4e-05 23.8 0.3 0.62 10.3 0.0 3.8 3 1 1 4 4 4 1 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 KFQ97752.1 - 6.6e-05 22.9 0.1 0.86 9.8 0.0 3.3 3 1 0 3 3 3 2 RNA recognition motif RRM_5 PF13893.6 KFQ97752.1 - 0.00034 20.2 0.1 0.48 10.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KFQ97752.1 - 0.0016 18.5 0.1 1.1 9.3 0.0 2.6 2 0 0 2 2 2 2 Limkain b1 RRM_occluded PF16842.5 KFQ97752.1 - 0.0076 16.1 0.1 7.2 6.5 0.0 3.0 3 0 0 3 3 3 2 Occluded RNA-recognition motif BRAP2 PF07576.12 KFQ97752.1 - 0.016 15.4 0.1 0.14 12.4 0.0 2.3 3 0 0 3 3 3 0 BRCA1-associated protein 2 SET_assoc PF11767.8 KFQ97752.1 - 0.032 13.9 0.1 7.7 6.2 0.1 2.4 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated dsrm PF00035.26 KFQ97752.1 - 0.056 14.2 0.5 3.2 8.5 0.1 3.0 2 1 0 2 2 2 0 Double-stranded RNA binding motif HEPN_AbiU2 PF18734.1 KFQ97752.1 - 0.11 12.0 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 AbiU2 Nup35_RRM_2 PF14605.6 KFQ97752.1 - 0.35 10.9 1.2 37 4.4 0.1 2.8 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Ceramidase_alk PF04734.13 KFQ97753.1 - 1.2e-229 763.1 0.0 1.5e-229 762.9 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KFQ97753.1 - 3.6e-49 166.8 0.1 5.4e-49 166.3 0.1 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Pga1 PF10333.9 KFQ97753.1 - 0.081 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 GPI-Mannosyltransferase II co-activator PAP2_C PF14360.6 KFQ97754.1 - 2.4e-29 101.7 15.1 2.4e-29 101.7 15.1 2.5 3 0 0 3 3 3 1 PAP2 superfamily C-terminal SAM_3 PF18016.1 KFQ97754.1 - 5.8e-07 29.2 0.0 1.6e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PAP2 PF01569.21 KFQ97754.1 - 6.1e-07 29.3 10.4 6.1e-07 29.3 10.4 1.9 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KFQ97754.1 - 1.4e-05 24.9 12.9 0.00016 21.4 9.2 2.4 2 0 0 2 2 2 2 PAP2 superfamily SAM_1 PF00536.30 KFQ97754.1 - 0.00015 22.1 0.0 0.00051 20.4 0.0 2.0 1 1 1 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFQ97754.1 - 0.0052 16.9 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFQ97754.1 - 0.04 13.9 1.5 0.19 11.7 0.2 2.8 3 1 0 3 3 3 0 Sterile alpha motif (SAM)/Pointed domain His_Phos_2 PF00328.22 KFQ97755.1 - 1.2e-21 77.5 0.1 1.5e-21 77.2 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF4708 PF15813.5 KFQ97755.1 - 0.03 13.5 0.2 0.082 12.0 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4708) APS_kinase PF01583.20 KFQ97756.1 - 3.5e-74 248.0 0.0 6e-74 247.2 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.17 KFQ97756.1 - 6.2e-68 228.4 0.0 8.9e-68 227.9 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 KFQ97756.1 - 3.7e-52 176.2 0.0 6.6e-52 175.4 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.6 KFQ97756.1 - 2.6e-05 24.4 0.0 5.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFQ97756.1 - 0.00042 20.8 0.0 0.0018 18.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KFQ97756.1 - 0.11 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 NTPase KTI12 PF08433.10 KFQ97756.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA PF00004.29 KFQ97757.1 - 1.7e-36 125.6 0.0 5.1e-36 124.0 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFQ97757.1 - 3.2e-12 46.0 0.1 7e-12 45.0 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KFQ97757.1 - 2e-05 24.4 0.0 7e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFQ97757.1 - 3.1e-05 24.3 0.9 0.081 13.2 0.1 2.9 2 1 1 3 3 3 2 AAA domain TniB PF05621.11 KFQ97757.1 - 5.3e-05 22.7 0.3 0.35 10.2 0.0 3.5 3 1 1 4 4 4 1 Bacterial TniB protein AAA_16 PF13191.6 KFQ97757.1 - 0.00014 22.3 1.0 0.0022 18.4 0.0 2.6 2 1 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 KFQ97757.1 - 0.00014 21.9 0.0 0.00032 20.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFQ97757.1 - 0.00015 21.8 0.1 0.0015 18.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KFQ97757.1 - 0.00032 20.3 0.2 0.85 9.2 0.0 2.6 3 0 0 3 3 2 2 AAA domain Rad17 PF03215.15 KFQ97757.1 - 0.0006 19.8 0.3 0.0057 16.6 0.3 2.4 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_18 PF13238.6 KFQ97757.1 - 0.0034 17.9 0.2 0.034 14.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 KFQ97757.1 - 0.0039 16.6 0.1 0.038 13.4 0.1 2.3 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KFQ97757.1 - 0.0093 15.5 0.1 0.061 12.8 0.0 2.3 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_33 PF13671.6 KFQ97757.1 - 0.011 15.9 0.0 0.022 14.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KFQ97757.1 - 0.015 15.4 0.0 0.062 13.4 0.0 2.0 2 1 0 2 2 1 0 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.12 KFQ97757.1 - 0.017 14.4 0.0 0.051 12.8 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.17 KFQ97757.1 - 0.019 14.7 0.0 0.058 13.1 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KFQ97757.1 - 0.023 15.1 0.0 0.049 14.0 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_21 PF13304.6 KFQ97757.1 - 0.03 14.1 0.3 0.14 11.9 0.1 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system TIP49 PF06068.13 KFQ97757.1 - 0.033 13.4 0.0 0.077 12.2 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_24 PF13479.6 KFQ97757.1 - 0.037 13.8 0.1 0.083 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 KFQ97757.1 - 0.043 13.8 0.1 0.35 10.9 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 KFQ97757.1 - 0.049 13.8 0.1 0.4 10.8 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 KFQ97757.1 - 0.053 13.0 0.0 0.92 8.9 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein SKI PF01202.22 KFQ97757.1 - 0.058 13.5 0.3 0.14 12.3 0.0 1.7 2 0 0 2 2 1 0 Shikimate kinase ABC_tran PF00005.27 KFQ97757.1 - 0.18 12.3 0.3 1.5 9.4 0.0 2.5 3 1 0 3 3 3 0 ABC transporter ATPase PF06745.13 KFQ97757.1 - 0.24 10.7 1.7 0.9 8.8 0.0 2.6 3 1 0 4 4 4 0 KaiC AAA_17 PF13207.6 KFQ97757.1 - 0.43 11.0 0.0 0.43 11.0 0.0 2.5 3 1 1 4 4 2 0 AAA domain PTEN_C2 PF10409.9 KFQ97758.1 - 2e-45 153.8 2.7 3.1e-45 153.3 2.7 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 KFQ97758.1 - 3.2e-08 33.5 0.1 1.9e-07 30.9 0.0 2.0 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFQ97758.1 - 0.00012 21.7 0.0 0.00032 20.3 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFQ97758.1 - 0.0025 17.8 0.0 0.0037 17.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFQ97758.1 - 0.0028 17.8 0.0 0.0062 16.7 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Amino_oxidase PF01593.24 KFQ97759.1 - 6.1e-08 32.4 0.0 9.5e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Abhydrolase_1 PF00561.20 KFQ97760.1 - 1.3e-21 77.4 0.3 2.5e-21 76.5 0.3 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KFQ97760.1 - 7.2e-16 57.5 0.0 1.6e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KFQ97760.1 - 2e-07 30.6 0.0 9.3e-07 28.4 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFQ97760.1 - 0.0018 18.9 0.2 0.0035 18.0 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Kelch_2 PF07646.15 KFQ97760.1 - 0.061 13.3 0.3 17 5.6 0.0 3.4 3 0 0 3 3 3 0 Kelch motif Kelch_1 PF01344.25 KFQ97760.1 - 0.094 12.3 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Kelch motif Abhydrolase_1 PF00561.20 KFQ97761.1 - 4e-26 92.2 0.5 6e-26 91.6 0.5 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KFQ97761.1 - 1.1e-18 66.5 0.0 2.6e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KFQ97761.1 - 2.4e-08 33.5 0.0 1.2e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 VirJ PF06057.11 KFQ97761.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Cutinase PF01083.22 KFQ97761.1 - 0.071 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Cutinase Lipase_2 PF01674.18 KFQ97761.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) MMR_HSR1 PF01926.23 KFQ97762.1 - 4.6e-13 49.3 0.0 7.1e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFQ97762.1 - 3.5e-07 30.3 0.0 0.0074 16.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KFQ97762.1 - 5e-07 29.4 0.1 5.3e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 KFQ97762.1 - 0.00054 20.4 0.1 0.0093 16.4 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain PduV-EutP PF10662.9 KFQ97762.1 - 0.00058 19.6 0.0 0.48 10.2 0.0 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 KFQ97762.1 - 0.0018 18.3 0.5 0.37 10.8 0.2 2.2 1 1 1 2 2 2 2 Dynamin family IIGP PF05049.13 KFQ97762.1 - 0.0032 16.6 0.0 0.0048 16.0 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 KFQ97762.1 - 0.0033 17.7 0.0 0.12 12.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain AIG1 PF04548.16 KFQ97762.1 - 0.0042 16.5 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 AIG1 family AAA_18 PF13238.6 KFQ97762.1 - 0.021 15.4 0.0 0.042 14.4 0.0 1.7 2 1 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 KFQ97762.1 - 0.035 13.9 0.1 6.9 6.4 0.0 2.8 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Ras PF00071.22 KFQ97762.1 - 0.045 13.3 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Ras family Roc PF08477.13 KFQ97762.1 - 0.052 13.8 0.0 0.17 12.1 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KFQ97762.1 - 0.077 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KFQ97762.1 - 0.096 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KFQ97762.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 KFQ97762.1 - 0.22 10.7 0.0 0.63 9.1 0.0 1.7 2 0 0 2 2 2 0 G-protein alpha subunit ECH_1 PF00378.20 KFQ97763.1 - 7.6e-66 222.0 0.5 8.6e-66 221.8 0.5 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFQ97763.1 - 4.7e-32 111.8 0.4 5.6e-32 111.5 0.4 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KFQ97763.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Peptidase family S49 PRAP PF15314.6 KFQ97764.1 - 1.7e-11 44.4 10.1 2.1e-11 44.1 10.1 1.1 1 0 0 1 1 1 1 Proline-rich acidic protein 1, pregnancy-specific uterine DUF629 PF04780.12 KFQ97765.1 - 0.18 10.3 0.1 0.22 10.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF629) GCP_C_terminal PF04130.13 KFQ97766.1 - 5.6e-83 278.9 13.7 5.6e-83 278.9 13.7 2.2 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KFQ97766.1 - 2e-77 260.9 1.4 2e-77 260.9 1.4 2.7 2 1 0 3 3 3 1 Gamma tubulin complex component N-terminal DASH_Ask1 PF08655.10 KFQ97766.1 - 0.093 12.6 0.1 0.67 9.9 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Ask1 zf-Tim10_DDP PF02953.15 KFQ97766.1 - 0.11 12.2 5.7 0.036 13.7 2.4 2.0 2 0 0 2 2 2 0 Tim10/DDP family zinc finger DUF2894 PF11445.8 KFQ97766.1 - 0.13 12.8 1.0 0.75 10.2 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) Adaptin_binding PF10199.9 KFQ97766.1 - 0.19 12.4 2.4 0.28 11.8 0.3 2.2 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Reprolysin PF01421.19 KFQ97767.1 - 6.6e-65 218.8 0.0 1.1e-64 218.0 0.0 1.4 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 KFQ97767.1 - 1.7e-22 80.2 0.2 2.7e-22 79.5 0.2 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide Disintegrin PF00200.23 KFQ97767.1 - 1.1e-19 71.0 31.9 1.1e-19 71.0 31.9 2.7 2 0 0 2 2 2 1 Disintegrin Reprolysin_5 PF13688.6 KFQ97767.1 - 4.2e-18 66.2 0.0 8.4e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFQ97767.1 - 1.2e-14 54.9 0.1 1.9e-14 54.2 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR PF08516.12 KFQ97767.1 - 6.1e-11 42.7 3.7 6.1e-11 42.7 3.7 2.6 2 0 0 2 2 1 1 ADAM cysteine-rich Reprolysin_2 PF13574.6 KFQ97767.1 - 6.9e-10 39.1 0.0 1.3e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFQ97767.1 - 4.6e-07 29.7 0.0 9.6e-07 28.6 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFQ97767.1 - 0.034 14.0 0.1 0.051 13.4 0.1 1.3 1 0 0 1 1 1 0 Matrixin DUF3810 PF12725.7 KFQ97767.1 - 0.11 11.8 0.4 0.17 11.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Peptidase_M66 PF10462.9 KFQ97767.1 - 0.22 10.4 0.1 0.38 9.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 IKBKB_SDD PF18397.1 KFQ97768.1 - 2.9e-137 456.5 9.7 3.8e-137 456.1 9.7 1.1 1 0 0 1 1 1 1 IQBAL scaffold dimerization domain Pkinase PF00069.25 KFQ97768.1 - 1.1e-48 165.9 0.0 2.3e-48 164.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ97768.1 - 4.4e-33 114.6 0.0 1e-32 113.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase IKKbetaNEMObind PF12179.8 KFQ97768.1 - 6.2e-16 58.2 3.4 6.2e-16 58.2 3.4 2.5 3 0 0 3 3 3 1 I-kappa-kinase-beta NEMO binding domain Pkinase_fungal PF17667.1 KFQ97768.1 - 1.3e-05 24.2 0.0 2.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase TBK1_ULD PF18396.1 KFQ97768.1 - 0.00028 20.7 0.1 0.00078 19.3 0.0 1.8 2 0 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain Kdo PF06293.14 KFQ97768.1 - 0.00035 20.0 0.0 0.00086 18.7 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFQ97768.1 - 0.0061 16.5 0.0 0.017 15.1 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF3887 PF13026.6 KFQ97768.1 - 0.069 14.0 0.2 0.2 12.5 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) PNMA PF14893.6 KFQ97768.1 - 0.074 12.4 0.8 0.13 11.7 0.8 1.4 1 0 0 1 1 1 0 PNMA LSM PF01423.22 KFQ97771.1 - 1.9e-16 59.5 0.5 2.5e-16 59.1 0.5 1.2 1 0 0 1 1 1 1 LSM domain CFTR_R PF14396.6 KFQ97772.1 - 3.5e-106 353.5 3.0 3.5e-106 353.5 3.0 1.9 2 0 0 2 2 2 1 Cystic fibrosis TM conductance regulator (CFTR), regulator domain ABC_membrane PF00664.23 KFQ97772.1 - 1.1e-93 313.9 39.9 3.6e-50 171.2 17.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFQ97772.1 - 1.3e-55 187.6 0.0 1.1e-30 106.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KFQ97772.1 - 7.9e-07 29.2 0.3 0.18 11.6 0.0 3.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFQ97772.1 - 1.6e-06 27.7 0.0 0.025 14.0 0.0 3.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 KFQ97772.1 - 2.9e-06 26.5 0.0 0.031 13.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 KFQ97772.1 - 2.5e-05 23.9 1.1 0.009 15.7 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFQ97772.1 - 2.9e-05 24.0 0.7 0.029 14.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 KFQ97772.1 - 0.00044 20.4 1.1 0.31 11.1 0.1 2.7 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_16 PF13191.6 KFQ97772.1 - 0.00044 20.7 0.0 1.2 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain NTPase_1 PF03266.15 KFQ97772.1 - 0.0014 18.6 0.4 0.2 11.5 0.0 3.1 3 0 0 3 3 3 1 NTPase NACHT PF05729.12 KFQ97772.1 - 0.0028 17.6 0.5 2.2 8.2 0.1 2.7 2 0 0 2 2 2 2 NACHT domain AAA_23 PF13476.6 KFQ97772.1 - 0.0054 17.2 11.7 0.44 11.0 0.1 3.8 4 0 0 4 4 3 2 AAA domain MeaB PF03308.16 KFQ97772.1 - 0.0071 15.4 0.4 0.14 11.1 0.1 2.4 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KFQ97772.1 - 0.0095 16.0 0.1 1.1 9.3 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KFQ97772.1 - 0.011 16.0 0.4 8.8 6.6 0.1 3.0 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 KFQ97772.1 - 0.017 14.4 0.5 0.78 8.9 0.1 2.8 3 0 0 3 3 2 0 NB-ARC domain AAA_30 PF13604.6 KFQ97772.1 - 0.019 14.7 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KFQ97772.1 - 0.02 14.2 0.4 0.73 9.1 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 KFQ97772.1 - 0.041 13.4 0.1 7.2 6.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 KFQ97772.1 - 0.055 13.5 0.3 8.6 6.4 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TrwB_AAD_bind PF10412.9 KFQ97772.1 - 0.11 11.4 0.9 3.6 6.4 0.1 2.9 2 1 1 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 KFQ97772.1 - 0.13 11.9 1.4 6 6.4 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 KFQ97772.1 - 0.14 12.6 0.0 24 5.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.6 KFQ97772.1 - 0.17 12.2 0.0 20 5.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain MobB PF03205.14 KFQ97772.1 - 0.23 11.4 1.4 34 4.3 0.1 3.3 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Ank_2 PF12796.7 KFQ97773.1 - 2.7e-32 111.2 6.8 1.9e-15 57.2 0.3 3.4 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFQ97773.1 - 1.9e-24 85.0 1.6 4.5e-07 30.0 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KFQ97773.1 - 2e-22 78.9 1.3 2.2e-11 43.8 0.1 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ97773.1 - 5.8e-19 66.2 1.6 0.0002 21.6 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KFQ97773.1 - 1.1e-17 64.1 2.2 2.3e-07 31.2 0.1 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) SAM_1 PF00536.30 KFQ97773.1 - 4.2e-09 36.7 0.4 8.2e-09 35.8 0.4 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFQ97773.1 - 1.1e-08 35.0 0.4 2.5e-08 33.9 0.4 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) KASH_CCD PF14662.6 KFQ97773.1 - 0.046 13.5 0.0 0.046 13.5 0.0 2.9 3 1 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF643 PF04867.12 KFQ97773.1 - 0.06 14.0 0.2 0.12 13.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF643) wnt PF00110.19 KFQ97774.1 - 2.7e-118 395.0 25.9 3e-118 394.9 25.9 1.0 1 0 0 1 1 1 1 wnt family ST7 PF04184.12 KFQ97775.1 - 1.9e-277 921.0 2.5 2.2e-277 920.8 2.5 1.0 1 0 0 1 1 1 1 ST7 protein TPR_6 PF13174.6 KFQ97775.1 - 0.0004 20.8 0.0 0.0021 18.6 0.0 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Clathrin PF00637.20 KFQ97775.1 - 0.047 13.6 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Region in Clathrin and VPS TPR_19 PF14559.6 KFQ97775.1 - 0.11 13.0 4.7 0.3 11.6 0.2 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ97775.1 - 0.14 12.4 5.6 3.4 8.0 0.0 4.5 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ97775.1 - 0.14 12.0 2.8 23 5.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat F-actin_cap_A PF01267.17 KFQ97776.1 - 5.2e-107 357.2 2.4 5.9e-107 357.0 2.4 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit DUF5121 PF17165.4 KFQ97776.1 - 0.053 13.9 0.3 0.15 12.5 0.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5121) CCP_MauG PF03150.14 KFQ97776.1 - 0.068 13.8 0.9 0.26 11.9 0.5 2.1 1 1 1 2 2 2 0 Di-haem cytochrome c peroxidase Pkinase_Tyr PF07714.17 KFQ97778.1 - 4.8e-94 314.5 0.0 6.9e-94 313.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Sema PF01403.19 KFQ97778.1 - 1.1e-51 176.0 4.0 1.8e-51 175.4 4.0 1.2 1 0 0 1 1 1 1 Sema domain Pkinase PF00069.25 KFQ97778.1 - 1.5e-39 136.0 0.0 3e-39 135.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain TIG PF01833.24 KFQ97778.1 - 5.4e-34 116.1 11.0 6.6e-14 51.8 0.1 4.9 4 0 0 4 4 4 4 IPT/TIG domain Kinase-like PF14531.6 KFQ97778.1 - 7.8e-05 22.1 0.1 0.00029 20.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like PSI PF01437.25 KFQ97778.1 - 0.00013 22.4 17.2 0.00013 22.4 17.2 2.4 2 0 0 2 2 2 1 Plexin repeat Pkinase_fungal PF17667.1 KFQ97778.1 - 0.0054 15.6 0.0 0.0082 15.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF4521 PF15021.6 KFQ97778.1 - 0.15 12.0 0.1 0.31 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) Caveolin PF01146.17 KFQ97779.1 - 1.5e-51 173.8 5.0 1.7e-51 173.6 5.0 1.0 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.17 KFQ97780.1 - 1.9e-48 163.8 6.7 2.1e-48 163.6 6.7 1.0 1 0 0 1 1 1 1 Caveolin PET PF06297.14 KFQ97781.1 - 7.3e-41 138.4 3.1 1.2e-40 137.7 3.1 1.4 1 0 0 1 1 1 1 PET Domain LIM PF00412.22 KFQ97781.1 - 1.4e-27 95.6 60.4 1.5e-13 50.7 10.3 4.7 4 2 0 4 4 4 3 LIM domain SHIRT PF18655.1 KFQ97781.1 - 0.025 15.2 1.1 0.67 10.6 0.1 2.5 2 0 0 2 2 2 0 SHIRT domain Ig_Tie2_1 PF10430.9 KFQ97781.1 - 0.045 14.2 0.5 0.17 12.4 0.0 2.2 2 0 0 2 2 2 0 Tie-2 Ig-like domain 1 DUF3371 PF11851.8 KFQ97782.1 - 5.7e-34 118.0 5.7 5.7e-34 118.0 5.7 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3371) HLH PF00010.26 KFQ97782.1 - 1.4e-15 57.0 0.3 3.1e-15 55.9 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MITF_TFEB_C_3_N PF15951.5 KFQ97782.1 - 5.3e-14 53.1 1.0 5.3e-14 53.1 1.0 2.4 2 0 0 2 2 2 1 MITF/TFEB/TFEC/TFE3 N-terminus PGBA_C PF15437.6 KFQ97782.1 - 8.1 6.9 10.3 21 5.6 1.9 2.8 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal MDFI PF15316.6 KFQ97784.1 - 2.1e-73 246.0 36.8 2.1e-73 246.0 36.8 1.4 2 0 0 2 2 2 1 MyoD family inhibitor Forkhead PF00250.18 KFQ97785.1 - 4.6e-36 122.9 0.0 5.3e-36 122.7 0.0 1.0 1 0 0 1 1 1 1 Forkhead domain Linker_histone PF00538.19 KFQ97785.1 - 0.042 14.2 0.0 0.063 13.6 0.0 1.3 1 0 0 1 1 1 0 linker histone H1 and H5 family CBM_21 PF03370.13 KFQ97786.1 - 1.8e-29 102.2 0.4 4.5e-29 100.9 0.1 1.9 2 0 0 2 2 2 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KFQ97786.1 - 1.3e-07 32.1 0.1 4.2e-07 30.5 0.1 1.9 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) DUF4730 PF15873.5 KFQ97788.1 - 3.3e-21 75.3 4.1 3.8e-21 75.1 4.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4730) FixS PF03597.15 KFQ97788.1 - 0.42 10.3 4.0 3.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Antimicrobial10 PF08105.11 KFQ97788.1 - 2.4 8.3 4.3 1.4 9.0 1.5 1.8 1 1 1 2 2 2 0 Metchnikowin family Bmt2 PF11968.8 KFQ97789.1 - 6e-08 32.8 0.3 3.3e-05 23.8 0.3 2.1 1 1 1 2 2 2 2 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 COX7a PF02238.15 KFQ97790.1 - 1.9 8.9 5.3 5.7 7.4 0.3 3.1 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VII CrgA PF06781.12 KFQ97790.1 - 9.9 6.3 13.9 0.83 9.7 4.0 3.3 2 1 0 2 2 2 0 Cell division protein CrgA DUF4577 PF15145.6 KFQ97791.1 - 4.3e-46 156.1 1.1 4.7e-46 156.0 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4577) SieB PF14163.6 KFQ97791.1 - 0.0042 16.6 0.5 0.0061 16.1 0.5 1.2 1 0 0 1 1 1 1 Super-infection exclusion protein B MscL PF01741.18 KFQ97791.1 - 0.0077 16.5 0.1 0.0083 16.4 0.1 1.2 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL Tetraspanin PF00335.20 KFQ97791.1 - 0.0081 15.9 0.8 0.011 15.5 0.8 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF948 PF06103.11 KFQ97791.1 - 0.022 15.0 0.9 0.043 14.1 0.9 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) COX2_TM PF02790.15 KFQ97791.1 - 0.029 14.5 0.2 0.045 13.9 0.2 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain DUF5345 PF17280.2 KFQ97791.1 - 0.081 12.9 0.6 0.2 11.7 0.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5345) IFRD PF05004.13 KFQ97792.1 - 7.7e-111 370.1 6.0 9.3e-111 369.8 6.0 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.12 KFQ97792.1 - 3.3e-24 85.2 0.7 3.3e-24 85.2 0.7 2.2 2 0 0 2 2 2 1 Interferon-related protein conserved region HEAT PF02985.22 KFQ97792.1 - 0.025 14.8 0.6 17 6.0 0.1 3.1 3 0 0 3 3 3 0 HEAT repeat zf-C2H2_2 PF12756.7 KFQ97793.1 - 4.2e-47 158.6 25.2 2.3e-23 82.4 7.0 3.2 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFQ97793.1 - 9.6e-11 41.6 23.7 0.0013 19.4 0.4 5.7 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ97793.1 - 8.2e-05 22.8 2.4 8.2e-05 22.8 2.4 4.2 5 0 0 5 5 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KFQ97793.1 - 0.00049 20.4 1.6 0.00049 20.4 1.6 5.8 5 2 0 5 5 5 2 Zinc finger, C2H2 type zf-BED PF02892.15 KFQ97793.1 - 0.0045 17.0 1.4 0.0045 17.0 1.4 5.1 5 0 0 5 5 5 2 BED zinc finger zf-C2H2_11 PF16622.5 KFQ97793.1 - 0.018 14.8 11.5 0.52 10.1 0.2 3.8 3 0 0 3 3 3 0 zinc-finger C2H2-type YokU PF14122.6 KFQ97793.1 - 0.034 14.1 0.0 0.034 14.1 0.0 2.6 3 0 0 3 3 2 0 YokU-like protein, putative antitoxin zf-met PF12874.7 KFQ97793.1 - 0.078 13.4 1.3 0.078 13.4 1.3 4.1 4 1 0 4 4 3 0 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 KFQ97793.1 - 0.091 13.4 15.7 12 6.6 0.3 5.1 2 1 3 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 KFQ97793.1 - 0.12 12.6 24.6 3.8 7.9 1.1 5.6 5 1 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-DBF PF07535.12 KFQ97793.1 - 0.13 12.4 8.0 1.2 9.3 0.3 3.0 2 0 0 2 2 2 0 DBF zinc finger CpXC PF14353.6 KFQ97793.1 - 1.1 9.3 10.6 2.5 8.2 0.3 3.7 2 1 2 4 4 4 0 CpXC protein Kazal_1 PF00050.21 KFQ97793.1 - 1.8 8.6 10.3 0.92 9.6 0.1 4.3 4 0 0 4 4 4 0 Kazal-type serine protease inhibitor domain FOXP-CC PF16159.5 KFQ97793.1 - 4.2 8.1 15.6 34 5.2 0.5 5.3 5 0 0 5 5 5 0 FOXP coiled-coil domain DHR-2 PF06920.13 KFQ97794.1 - 1.9e-110 370.0 7.9 1.3e-109 367.3 7.9 2.1 1 1 0 1 1 1 1 Dock homology region 2 DOCK_N PF16172.5 KFQ97794.1 - 7.4e-102 341.1 0.0 1.5e-101 340.1 0.0 1.6 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 KFQ97794.1 - 1.3e-53 181.7 0.0 3e-52 177.3 0.0 2.7 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins SH3_2 PF07653.17 KFQ97794.1 - 0.0028 17.3 0.1 0.0091 15.7 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFQ97794.1 - 0.0031 17.1 0.0 0.0063 16.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFQ97794.1 - 0.0056 16.5 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_S24 PF00717.23 KFQ97795.1 - 2.2e-09 37.2 0.2 5.4e-09 35.9 0.2 1.7 1 1 0 1 1 1 1 Peptidase S24-like LRR_8 PF13855.6 KFQ97796.1 - 6.6e-41 137.9 68.7 2.1e-13 49.8 5.3 7.0 2 1 7 9 9 9 8 Leucine rich repeat LRR_5 PF13306.6 KFQ97796.1 - 1.8e-21 76.4 0.2 1.1e-08 35.0 0.0 3.6 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFQ97796.1 - 1e-19 70.2 47.5 0.00015 22.0 3.1 7.9 6 2 0 7 7 6 5 Leucine Rich repeats (2 copies) I-set PF07679.16 KFQ97796.1 - 1.5e-12 47.4 0.0 5.1e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ97796.1 - 2.2e-12 47.4 0.0 5.7e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.6 KFQ97796.1 - 1.4e-10 40.9 25.5 8.1e-05 22.2 0.6 4.4 1 1 3 4 4 4 4 Leucine-rich repeat ig PF00047.25 KFQ97796.1 - 3.3e-08 33.6 0.0 6.8e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.21 KFQ97796.1 - 1.4e-07 31.8 0.1 2.9e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Ig_2 PF13895.6 KFQ97796.1 - 4.5e-06 26.9 0.0 1.1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain LRRCT PF01463.24 KFQ97796.1 - 0.0019 18.6 0.1 0.0048 17.3 0.1 1.7 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain V-set PF07686.17 KFQ97796.1 - 0.0035 17.5 0.2 0.43 10.8 0.1 2.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 KFQ97796.1 - 0.096 13.3 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain LRRNT PF01462.18 KFQ97796.1 - 0.55 9.9 7.9 0.069 12.8 1.1 3.2 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain DnaJ PF00226.31 KFQ97799.1 - 2.5e-28 98.0 2.2 4.6e-28 97.1 2.2 1.4 1 0 0 1 1 1 1 DnaJ domain THAP PF05485.12 KFQ97800.1 - 6.4e-10 39.8 0.2 2.1e-09 38.2 0.2 2.0 1 0 0 1 1 1 1 THAP domain 7tm_1 PF00001.21 KFQ97801.1 - 6.5e-41 140.4 23.3 7.9e-41 140.1 23.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ97801.1 - 0.0013 18.2 24.4 0.0032 16.9 24.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Patatin PF01734.22 KFQ97802.1 - 1e-22 81.4 0.0 7.5e-22 78.5 0.0 2.3 2 0 0 2 2 2 1 Patatin-like phospholipase SMC_ScpB PF04079.16 KFQ97802.1 - 0.02 14.5 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB DUF4795 PF16043.5 KFQ97802.1 - 0.72 9.4 11.8 3.3 7.3 0.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) Ig_3 PF13927.6 KFQ97803.1 - 1.1e-75 250.2 0.3 1e-12 48.4 0.2 7.0 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 KFQ97803.1 - 3.8e-70 232.0 0.0 8.9e-13 48.1 0.0 7.0 7 0 0 7 7 6 6 Immunoglobulin I-set domain fn3 PF00041.21 KFQ97803.1 - 2.3e-63 210.6 15.6 3.2e-14 53.0 0.1 5.6 5 0 0 5 5 5 5 Fibronectin type III domain Ig_2 PF13895.6 KFQ97803.1 - 2.2e-47 159.3 0.1 7.8e-08 32.5 0.0 6.5 5 1 1 6 6 6 6 Immunoglobulin domain ig PF00047.25 KFQ97803.1 - 3.3e-44 149.0 0.0 2e-07 31.1 0.0 6.8 6 0 0 6 6 6 6 Immunoglobulin domain Bravo_FIGEY PF13882.6 KFQ97803.1 - 6.8e-27 94.7 6.8 1.5e-26 93.6 6.8 1.6 1 0 0 1 1 1 1 Bravo-like intracellular region V-set PF07686.17 KFQ97803.1 - 5.7e-13 49.0 3.2 0.054 13.7 0.0 8.9 8 3 0 8 8 8 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFQ97803.1 - 4.4e-12 45.9 0.0 0.16 12.1 0.0 6.3 6 0 0 6 6 6 3 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFQ97803.1 - 6.3e-10 38.5 0.8 0.79 9.3 0.0 5.9 6 0 0 6 6 6 3 Immunoglobulin domain Ig_5 PF16681.5 KFQ97803.1 - 7.3e-07 29.5 0.0 0.8 10.2 0.0 5.5 6 1 0 6 6 5 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFQ97803.1 - 1.1e-06 28.8 0.1 2 8.7 0.0 5.4 6 0 0 6 6 5 2 T-cell surface glycoprotein CD3 delta chain Pur_ac_phosph_N PF16656.5 KFQ97803.1 - 2.1e-06 28.2 3.9 0.031 14.8 0.1 5.6 5 0 0 5 5 5 1 Purple acid Phosphatase, N-terminal domain V-set_CD47 PF08204.11 KFQ97803.1 - 0.0022 18.0 2.8 3.2 7.7 0.0 3.8 4 0 0 4 4 4 1 CD47 immunoglobulin-like domain Adeno_E3_CR1 PF02440.15 KFQ97803.1 - 0.0023 17.7 3.3 0.17 11.7 0.0 4.2 5 0 0 5 5 4 1 Adenovirus E3 region protein CR1 SIT PF15330.6 KFQ97803.1 - 0.0068 16.8 0.0 0.34 11.4 0.0 2.5 2 0 0 2 2 2 1 SHP2-interacting transmembrane adaptor protein, SIT Izumo-Ig PF16706.5 KFQ97803.1 - 0.012 15.7 0.0 4.1 7.5 0.0 3.7 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain DUF5640 PF18692.1 KFQ97803.1 - 0.14 12.2 0.1 19 5.4 0.0 3.8 3 0 0 3 3 3 0 Family of unknown function (DUF5640) INCA1 PF15142.6 KFQ97803.1 - 0.15 12.1 0.1 0.4 10.7 0.1 1.7 1 0 0 1 1 1 0 INCA1 Ig_3 PF13927.6 KFQ97804.1 - 3.1e-64 213.5 0.0 1.2e-11 45.0 0.0 7.2 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 KFQ97804.1 - 1.6e-58 194.8 0.5 9.2e-12 44.9 0.0 8.3 7 1 0 7 7 7 6 Immunoglobulin I-set domain fn3 PF00041.21 KFQ97804.1 - 9.3e-45 150.9 10.8 4.8e-17 62.1 1.0 4.7 4 0 0 4 4 4 4 Fibronectin type III domain ig PF00047.25 KFQ97804.1 - 1.4e-41 140.5 0.0 8.2e-10 38.7 0.0 7.3 5 2 1 6 6 6 6 Immunoglobulin domain Ig_2 PF13895.6 KFQ97804.1 - 8.4e-39 131.8 0.2 2.4e-07 31.0 0.0 6.5 5 1 1 6 6 6 5 Immunoglobulin domain V-set PF07686.17 KFQ97804.1 - 2.7e-24 85.4 11.2 0.0052 16.9 0.1 10.4 8 4 1 9 9 8 5 Immunoglobulin V-set domain Ig_5 PF16681.5 KFQ97804.1 - 1.4e-10 41.4 0.0 0.39 11.2 0.0 6.5 6 0 0 6 6 6 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFQ97804.1 - 1.6e-10 40.4 0.4 0.52 9.9 0.0 5.9 6 0 0 6 6 6 3 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFQ97804.1 - 1.6e-08 35.0 6.9 2.4e-05 24.8 1.1 3.5 3 1 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Ig_4 PF16680.5 KFQ97804.1 - 1.6e-07 31.5 0.0 2.2 8.6 0.0 5.0 5 0 0 5 5 5 3 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFQ97804.1 - 1.8e-07 31.1 0.2 2.4 8.3 0.0 6.2 7 0 0 7 7 7 1 Izumo-like Immunoglobulin domain Adeno_E3_CR1 PF02440.15 KFQ97804.1 - 1.1e-05 25.1 6.3 1.5 8.6 0.0 6.1 6 1 0 6 6 6 1 Adenovirus E3 region protein CR1 Interfer-bind PF09294.10 KFQ97804.1 - 1.5e-05 25.3 0.0 0.0092 16.3 0.0 3.5 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.17 KFQ97804.1 - 0.0017 18.2 2.3 0.41 10.5 0.0 4.4 3 2 1 4 4 4 1 Tissue factor C2-set_2 PF08205.12 KFQ97804.1 - 0.002 18.2 0.0 4.4 7.5 0.0 3.4 4 0 0 4 4 3 1 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 KFQ97804.1 - 0.0021 18.0 0.0 6.1 7.0 0.0 5.1 5 1 0 5 5 5 1 C17orf99 Ig domain CBM_35 PF16990.5 KFQ97804.1 - 0.0054 17.0 0.1 0.096 13.0 0.0 3.0 3 0 0 3 3 2 1 Carbohydrate binding module (family 35) DUF4998 PF16389.5 KFQ97804.1 - 0.0057 16.3 0.4 0.016 14.8 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function Big_3_4 PF13754.6 KFQ97804.1 - 0.023 14.4 0.0 0.13 12.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF2369 PF10179.9 KFQ97804.1 - 0.086 13.2 0.1 2.9 8.3 0.0 2.8 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2369) PKD PF00801.20 KFQ97804.1 - 0.7 9.8 2.9 10 6.1 0.0 3.9 4 0 0 4 4 4 0 PKD domain PDZ PF00595.24 KFQ97805.1 - 1.9e-20 73.0 0.2 2.2e-15 56.8 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFQ97805.1 - 1.2e-15 57.1 1.5 3.4e-13 49.2 0.3 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFQ97805.1 - 6.6e-07 29.6 0.1 2.3e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 KFQ97805.1 - 0.02 14.8 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain Glyco_transf_8 PF01501.20 KFQ97806.1 - 1e-07 31.8 0.6 2e-07 30.9 0.6 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KFQ97806.1 - 0.024 14.1 0.1 0.037 13.4 0.1 1.4 1 1 0 1 1 1 0 Glucosyltransferase 24 YAF2_RYBP PF17219.3 KFQ97807.1 - 1.1e-19 69.6 0.2 1.8e-19 69.0 0.2 1.4 1 0 0 1 1 1 1 Yaf2/RYBP C-terminal binding motif U3_snoRNA_assoc PF08297.11 KFQ97807.1 - 0.53 11.0 11.9 1.1 10.0 11.9 1.6 1 1 0 1 1 1 0 U3 snoRNA associated CPSF100_C PF13299.6 KFQ97807.1 - 4.4 7.4 9.4 1.1 9.5 5.7 1.7 1 1 1 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RAP1 PF07218.11 KFQ97807.1 - 6.8 4.8 11.5 7.5 4.7 11.5 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RRM_1 PF00076.22 KFQ97808.1 - 3.1e-22 78.2 0.2 5e-22 77.5 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFQ97808.1 - 7.3e-09 35.3 0.0 1.2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KFQ97808.1 - 3.2e-05 23.8 2.0 5.6e-05 23.0 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle SET_assoc PF11767.8 KFQ97808.1 - 0.01 15.5 0.0 0.026 14.2 0.0 1.7 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated zf-CCHC_3 PF13917.6 KFQ97808.1 - 0.013 15.5 0.8 0.024 14.6 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle BRAP2 PF07576.12 KFQ97808.1 - 0.015 15.5 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 BRCA1-associated protein 2 RRM_7 PF16367.5 KFQ97808.1 - 0.02 15.0 0.0 0.051 13.7 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif RRM_occluded PF16842.5 KFQ97808.1 - 0.025 14.4 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KFQ97808.1 - 0.037 14.1 0.3 0.16 12.0 0.3 2.0 1 1 0 1 1 1 0 Limkain b1 PET PF06297.14 KFQ97809.1 - 5.4e-39 132.4 1.1 1.6e-38 130.9 1.1 1.9 1 0 0 1 1 1 1 PET Domain LIM PF00412.22 KFQ97809.1 - 3.5e-25 88.0 40.3 2e-09 37.5 3.3 3.7 3 0 0 3 3 3 3 LIM domain Vasculin PF15337.6 KFQ97809.1 - 0.0027 18.5 0.8 0.015 16.2 0.0 2.5 2 0 0 2 2 2 1 Vascular protein family Vasculin-like 1 TruD PF01142.18 KFQ97811.1 - 3.5e-70 236.9 0.0 4.8e-70 236.5 0.0 1.1 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) R3H PF01424.22 KFQ97811.1 - 0.0024 17.8 0.2 0.015 15.3 0.0 2.5 3 0 0 3 3 3 1 R3H domain Pkinase PF00069.25 KFQ97812.1 - 4.1e-52 177.2 0.0 5.5e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ97812.1 - 1.2e-48 165.7 0.0 2.2e-48 164.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFQ97812.1 - 0.00011 21.1 0.0 0.00018 20.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Focal_AT PF03623.13 KFQ97812.1 - 0.021 14.8 0.1 0.044 13.8 0.1 1.4 1 0 0 1 1 1 0 Focal adhesion targeting region Death PF00531.22 KFQ97812.1 - 0.021 14.9 0.0 0.055 13.6 0.0 1.6 1 0 0 1 1 1 0 Death domain Cofilin_ADF PF00241.20 KFQ97813.1 - 1.3e-43 147.7 0.1 6.1e-21 74.5 0.0 2.4 2 1 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein TMEM117 PF15113.6 KFQ97814.1 - 4.5e-229 760.3 27.5 5.2e-229 760.1 27.5 1.0 1 0 0 1 1 1 1 TMEM117 protein family 7tm_1 PF00001.21 KFQ97815.1 - 2.6e-31 108.9 21.8 3.8e-31 108.4 21.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PHO4 PF01384.20 KFQ97815.1 - 4.9 6.1 6.0 7.2 5.5 6.0 1.5 1 1 0 1 1 1 0 Phosphate transporter family EGF_CA PF07645.15 KFQ97816.1 - 5.3e-29 100.2 65.6 1.5e-11 44.3 7.2 10.2 8 2 1 9 9 8 5 Calcium-binding EGF domain VWC PF00093.18 KFQ97816.1 - 3.5e-18 65.7 63.0 2.6e-10 40.5 14.0 10.3 6 1 2 8 8 5 4 von Willebrand factor type C domain EGF_3 PF12947.7 KFQ97816.1 - 9.2e-14 51.4 38.6 1.3e-08 34.9 14.1 10.4 10 2 1 11 11 9 5 EGF domain cEGF PF12662.7 KFQ97816.1 - 1.3e-09 37.8 11.9 1.1e-07 31.7 3.3 10.3 10 0 0 10 10 10 5 Complement Clr-like EGF-like Laminin_G_2 PF02210.24 KFQ97816.1 - 2.1e-07 31.5 0.1 3.7e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 Laminin G domain EGF PF00008.27 KFQ97816.1 - 2.4e-06 27.7 21.0 6.2e-05 23.2 8.4 11.1 12 1 1 13 13 8 5 EGF-like domain hEGF PF12661.7 KFQ97816.1 - 4.3e-05 24.0 29.9 0.0018 18.9 5.9 12.1 12 0 0 12 12 10 5 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 KFQ97816.1 - 0.00015 21.7 8.8 0.00015 21.7 8.8 9.1 11 0 0 11 11 10 3 MSP1 EGF domain 1 TILa PF12714.7 KFQ97816.1 - 0.00018 21.4 23.8 0.00081 19.3 6.7 11.4 8 5 2 10 10 7 3 TILa domain Laminin_G_3 PF13385.6 KFQ97816.1 - 0.00019 21.6 0.0 0.00034 20.8 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_1 PF00054.23 KFQ97816.1 - 0.00029 21.0 0.0 0.00074 19.7 0.0 1.7 1 1 0 1 1 1 1 Laminin G domain FXa_inhibition PF14670.6 KFQ97816.1 - 0.017 15.4 6.4 0.017 15.4 6.4 10.5 7 2 3 10 10 9 0 Coagulation Factor Xa inhibitory site Hormone_1 PF00103.20 KFQ97817.1 - 1.2e-22 80.7 1.6 1.4e-22 80.5 1.6 1.1 1 0 0 1 1 1 1 Somatotropin hormone family Mer2 PF09074.10 KFQ97817.1 - 0.014 15.2 0.8 0.014 15.2 0.8 1.0 1 0 0 1 1 1 0 Mer2 Mating_N PF12731.7 KFQ97817.1 - 0.021 14.9 0.3 0.06 13.4 0.1 1.8 2 0 0 2 2 2 0 Mating-type protein beta 1 Homeodomain PF00046.29 KFQ97818.1 - 8.8e-21 73.5 5.5 1.9e-20 72.5 5.5 1.5 1 0 0 1 1 1 1 Homeodomain DUF2986 PF11661.8 KFQ97818.1 - 0.0036 17.8 1.8 0.0076 16.7 0.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2986) Homeobox_KN PF05920.11 KFQ97818.1 - 0.036 14.0 0.3 0.036 14.0 0.3 2.1 3 0 0 3 3 3 0 Homeobox KN domain Anoctamin PF04547.12 KFQ97819.1 - 8.2e-155 516.0 21.1 1e-154 515.7 21.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KFQ97819.1 - 1.6e-73 247.2 2.7 2.9e-73 246.3 2.7 1.5 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DUF2207 PF09972.9 KFQ97819.1 - 0.0075 15.1 8.1 0.22 10.2 0.1 2.6 3 0 0 3 3 3 2 Predicted membrane protein (DUF2207) Ctr PF04145.15 KFQ97819.1 - 2.3 8.8 6.4 32 5.1 0.1 3.5 3 1 0 4 4 4 0 Ctr copper transporter family ARID PF01388.21 KFQ97820.1 - 7.6e-25 87.4 0.3 2.8e-24 85.6 0.0 2.2 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain RFX_DNA_binding PF02257.15 KFQ97820.1 - 1.9e-23 82.9 0.1 3.8e-23 81.9 0.1 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain BAF250_C PF12031.8 KFQ97820.1 - 0.54 9.5 6.6 1 8.6 0.6 3.0 1 1 1 2 2 2 0 SWI/SNF-like complex subunit BAF250/Osa Aa_trans PF01490.18 KFQ97822.1 - 2.1e-77 260.6 38.3 2.6e-77 260.3 38.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Cation_ATPase_C PF00689.21 KFQ97822.1 - 8.4e-05 22.3 10.4 8.4e-05 22.3 10.4 3.1 2 2 1 3 3 3 1 Cation transporting ATPase, C-terminus Aa_trans PF01490.18 KFQ97823.1 - 8.4e-78 261.9 40.9 1.1e-77 261.5 40.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UPF0016 PF01169.19 KFQ97823.1 - 0.81 10.1 12.0 1.6 9.1 0.8 3.4 3 1 0 3 3 3 0 Uncharacterized protein family UPF0016 S_100 PF01023.19 KFQ97833.1 - 1.3e-20 72.8 0.8 1.9e-20 72.3 0.8 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_7 PF13499.6 KFQ97833.1 - 6.6e-05 23.3 1.9 0.00015 22.1 1.9 1.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFQ97833.1 - 0.00024 20.4 2.3 0.0004 19.7 0.3 2.4 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 KFQ97833.1 - 0.014 15.3 0.4 1.3 9.2 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain EF-hand_4 PF12763.7 KFQ97833.1 - 0.023 14.6 0.8 0.031 14.2 0.8 1.3 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand zf-H2C2_2 PF13465.6 KFQ97834.1 - 7.6e-57 187.4 32.1 6.7e-10 38.9 0.3 6.2 6 0 0 6 6 6 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ97834.1 - 3.4e-36 121.7 34.1 1.3e-05 25.4 1.0 7.1 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ97834.1 - 1.1e-21 75.6 37.4 0.0023 18.6 0.9 7.0 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ97834.1 - 3.5e-12 46.3 11.4 0.0045 17.3 0.0 6.3 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KFQ97834.1 - 1e-07 31.9 15.8 0.048 13.8 0.3 5.0 4 1 1 5 5 5 2 Zinc ribbon domain zf-Di19 PF05605.12 KFQ97834.1 - 6.2e-07 29.6 21.4 0.00021 21.5 1.8 3.8 1 1 5 6 6 6 4 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 KFQ97834.1 - 1.2e-05 24.8 15.2 0.23 11.1 0.1 6.2 6 0 0 6 6 6 1 Ubiquitin-Binding Zinc Finger FYVE PF01363.21 KFQ97834.1 - 1.3e-05 25.3 17.2 0.35 11.0 9.2 4.1 1 1 1 2 2 2 2 FYVE zinc finger Zn-C2H2_12 PF18112.1 KFQ97834.1 - 1.6e-05 25.2 6.0 1.7 9.2 0.0 4.1 4 0 0 4 4 3 2 Autophagy receptor zinc finger-C2H2 domain XPA_N PF01286.18 KFQ97834.1 - 5.4e-05 23.2 17.1 0.56 10.3 0.1 6.0 6 0 0 6 6 6 1 XPA protein N-terminal FdhE PF04216.12 KFQ97834.1 - 6.5e-05 23.0 9.8 0.016 15.2 0.7 2.9 1 1 1 2 2 2 2 Protein involved in formate dehydrogenase formation zf-C2H2_8 PF15909.5 KFQ97834.1 - 0.00014 22.1 14.4 0.018 15.3 1.6 3.3 1 1 2 3 3 3 2 C2H2-type zinc ribbon Prok-RING_1 PF14446.6 KFQ97834.1 - 0.00016 21.5 10.9 14 5.7 1.4 5.9 5 1 0 5 5 5 0 Prokaryotic RING finger family 1 zinc_ribbon_9 PF14369.6 KFQ97834.1 - 0.00016 21.8 9.4 1.9 8.8 0.0 5.6 6 0 0 6 6 6 1 zinc-ribbon C1_1 PF00130.22 KFQ97834.1 - 0.00019 21.3 15.4 0.79 9.7 2.4 4.7 1 1 3 5 5 5 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ribbon_3 PF13248.6 KFQ97834.1 - 0.00033 20.0 14.5 0.39 10.2 0.0 5.2 5 0 0 5 5 5 1 zinc-ribbon domain zf-C2H2_6 PF13912.6 KFQ97834.1 - 0.00042 20.2 41.5 0.36 10.9 0.8 7.7 7 2 0 7 7 7 4 C2H2-type zinc finger GAGA PF09237.11 KFQ97834.1 - 0.0005 19.8 10.8 1.1 9.2 0.1 4.2 2 2 3 5 5 5 3 GAGA factor zf-met PF12874.7 KFQ97834.1 - 0.00053 20.3 23.2 0.016 15.6 0.5 5.7 6 0 0 6 6 5 1 Zinc-finger of C2H2 type CpXC PF14353.6 KFQ97834.1 - 0.00069 19.6 14.8 12 5.9 0.1 5.8 2 1 4 6 6 6 0 CpXC protein zinc_ribbon_4 PF13717.6 KFQ97834.1 - 0.0016 18.3 16.2 7.4 6.6 0.0 5.9 6 0 0 6 6 6 0 zinc-ribbon domain DZR PF12773.7 KFQ97834.1 - 0.002 18.1 16.4 1.7e+02 2.4 0.2 4.0 1 1 1 2 2 2 0 Double zinc ribbon C1_4 PF07975.12 KFQ97834.1 - 0.0022 18.2 15.3 0.94 9.8 0.1 4.6 1 1 4 5 5 5 1 TFIIH C1-like domain zf-C2HC_2 PF13913.6 KFQ97834.1 - 0.0023 17.8 23.5 0.19 11.7 0.1 6.0 7 0 0 7 7 6 1 zinc-finger of a C2HC-type HypA PF01155.19 KFQ97834.1 - 0.0024 17.9 10.9 1.9 8.6 2.5 3.7 1 1 2 3 3 3 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA IBR PF01485.21 KFQ97834.1 - 0.0031 17.7 12.0 0.89 9.8 0.7 3.6 1 1 2 3 3 3 3 IBR domain, a half RING-finger domain DUF3268 PF11672.8 KFQ97834.1 - 0.0034 17.7 7.7 0.11 12.9 0.1 3.6 1 1 4 5 5 5 2 zinc-finger-containing domain Rad50_zn_hook PF04423.14 KFQ97834.1 - 0.0036 17.1 3.4 4.9 7.1 0.1 3.6 3 0 0 3 3 3 0 Rad50 zinc hook motif zinc-ribbons_6 PF07191.12 KFQ97834.1 - 0.0042 17.0 12.2 2.2 8.3 1.6 4.4 1 1 2 3 3 3 1 zinc-ribbons zinc_ribbon_15 PF17032.5 KFQ97834.1 - 0.0059 17.3 9.3 2.5 8.9 2.1 3.6 1 1 2 3 3 3 1 zinc-ribbon family ADK_lid PF05191.14 KFQ97834.1 - 0.0074 16.2 6.8 3.1 7.9 0.0 4.1 3 3 1 4 4 4 0 Adenylate kinase, active site lid Mut7-C PF01927.16 KFQ97834.1 - 0.01 16.0 12.8 4 7.5 0.1 4.8 1 1 3 4 4 4 0 Mut7-C RNAse domain BolA PF01722.18 KFQ97834.1 - 0.012 15.9 2.6 6 7.2 0.1 3.4 2 2 3 5 5 5 0 BolA-like protein FYDLN_acid PF09538.10 KFQ97834.1 - 0.018 15.7 8.6 37 5.1 0.4 5.5 1 1 4 5 5 5 0 Protein of unknown function (FYDLN_acid) Zn_ribbon_SprT PF17283.2 KFQ97834.1 - 0.02 14.8 21.0 0.49 10.4 0.2 5.3 5 1 0 5 5 5 0 SprT-like zinc ribbon domain Elf1 PF05129.13 KFQ97834.1 - 0.022 14.8 14.9 0.4 10.8 0.7 4.5 1 1 3 4 4 4 0 Transcription elongation factor Elf1 like Arc_trans_TRASH PF08394.10 KFQ97834.1 - 0.025 14.9 2.7 22 5.5 0.0 4.6 5 1 0 5 5 4 0 Archaeal TRASH domain Zf_RING PF16744.5 KFQ97834.1 - 0.032 14.4 13.2 2.5 8.3 0.1 5.2 1 1 5 6 6 6 0 KIAA1045 RING finger zf-RING_5 PF14634.6 KFQ97834.1 - 0.049 13.6 16.7 6.6 6.8 0.0 5.5 5 1 0 5 5 5 0 zinc-RING finger domain PHF5 PF03660.14 KFQ97834.1 - 0.054 13.7 4.2 1.5 9.1 0.4 3.0 1 1 3 4 4 4 0 PHF5-like protein zf-AN1 PF01428.16 KFQ97834.1 - 0.054 13.7 26.2 1.3 9.2 0.1 6.1 4 1 2 6 6 6 0 AN1-like Zinc finger Thioredoxin_4 PF13462.6 KFQ97834.1 - 0.16 12.1 3.2 6.1 7.0 0.2 2.7 3 0 0 3 3 2 0 Thioredoxin zf-LYAR PF08790.11 KFQ97834.1 - 0.2 11.6 10.9 2.6 8.0 0.1 4.7 6 0 0 6 6 4 0 LYAR-type C2HC zinc finger DUF2225 PF09986.9 KFQ97834.1 - 0.21 11.3 6.2 6.8 6.4 0.1 3.8 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_11 PF16622.5 KFQ97834.1 - 0.23 11.2 29.1 2.9 7.7 0.2 6.6 7 0 0 7 7 6 0 zinc-finger C2H2-type zf-trcl PF13451.6 KFQ97834.1 - 0.32 10.9 17.7 11 6.1 0.2 5.7 6 0 0 6 6 6 0 Probable zinc-ribbon domain zf_ZIC PF18366.1 KFQ97834.1 - 0.39 10.8 12.8 44 4.3 0.2 5.6 1 1 5 6 6 6 0 Zic proteins zinc finger domain LIM PF00412.22 KFQ97834.1 - 0.46 10.8 17.5 3.5 7.9 1.5 4.7 2 1 3 5 5 5 0 LIM domain YacG PF03884.14 KFQ97834.1 - 0.6 9.9 13.2 12 5.7 0.0 5.0 5 1 0 5 5 5 0 DNA gyrase inhibitor YacG YhfH PF14149.6 KFQ97834.1 - 0.74 9.9 12.2 17 5.5 0.1 4.8 5 0 0 5 5 4 0 YhfH-like protein Yippee-Mis18 PF03226.14 KFQ97834.1 - 1.4 9.1 9.2 1.9 8.7 1.2 3.7 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly NADH-G_4Fe-4S_3 PF10588.9 KFQ97834.1 - 1.6 8.4 12.5 38 3.9 0.1 4.7 5 0 0 5 5 4 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Ogr_Delta PF04606.12 KFQ97834.1 - 2.1 8.4 12.7 0.48 10.4 0.8 3.8 3 1 1 4 4 4 0 Ogr/Delta-like zinc finger zf-C2H2_9 PF16293.5 KFQ97834.1 - 2.1 8.3 10.0 7.7 6.4 0.1 4.3 4 1 1 5 5 4 0 C2H2 type zinc-finger (1 copy) zf-HIT PF04438.16 KFQ97834.1 - 2.7 7.9 22.5 4.7 7.2 0.5 5.5 6 0 0 6 6 6 0 HIT zinc finger TFIIS_C PF01096.18 KFQ97834.1 - 3 7.8 20.1 2.4 8.1 0.4 5.6 6 0 0 6 6 6 0 Transcription factor S-II (TFIIS) TRAF6_Z2 PF18048.1 KFQ97834.1 - 3.2 7.9 11.5 8.4 6.6 0.2 4.7 5 0 0 5 5 4 0 TNF receptor-associated factor 6 zinc finger 2 zf-WRNIP1_ubi PF18279.1 KFQ97834.1 - 3.4 8.5 11.6 4.5 8.1 0.1 4.9 5 1 0 5 5 4 0 Werner helicase-interacting protein 1 ubiquitin-binding domain DNA_ligase_ZBD PF03119.16 KFQ97834.1 - 3.4 7.8 9.3 5.1 7.2 0.1 3.7 4 0 0 4 4 3 0 NAD-dependent DNA ligase C4 zinc finger domain Zn_Tnp_IS1595 PF12760.7 KFQ97834.1 - 3.5 7.7 28.4 0.91 9.5 3.4 4.8 1 1 4 5 5 5 0 Transposase zinc-ribbon domain zf-C2H2_2 PF12756.7 KFQ97834.1 - 3.9 7.9 17.7 13 6.2 0.1 4.8 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) DUF2256 PF10013.9 KFQ97834.1 - 4.8 7.4 17.1 31 4.8 0.1 5.7 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-Paramyx-P PF13008.7 KFQ97834.1 - 9.3 5.8 21.1 36 3.9 0.1 5.5 5 1 0 5 5 5 0 Zinc-binding domain of Paramyxoviridae V protein PACT_coil_coil PF10495.9 KFQ97837.1 - 2.8e-28 98.3 0.1 4.3e-28 97.7 0.1 1.3 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein DNA_gyraseB PF00204.25 KFQ97838.1 - 0.077 12.5 4.6 0.095 12.2 4.4 1.3 1 1 0 1 1 1 0 DNA gyrase B FAM184 PF15665.5 KFQ97838.1 - 0.77 9.5 28.2 1.7 8.4 14.1 2.1 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B PKK PF12474.8 KFQ97838.1 - 2.9 8.0 31.0 0.29 11.3 23.9 2.0 1 1 1 2 2 2 0 Polo kinase kinase DUF445 PF04286.12 KFQ97838.1 - 3.5 7.4 13.6 4.3 7.1 13.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF4587 PF15248.6 KFQ97839.1 - 1.1e-32 112.6 10.7 1.1e-32 112.6 10.7 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF4587) FAD_binding_3 PF01494.19 KFQ97840.1 - 1.6e-21 76.9 0.0 2.7e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KFQ97840.1 - 8.6e-06 25.9 0.2 2.6e-05 24.4 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFQ97840.1 - 2.4e-05 24.1 0.2 8.1e-05 22.3 0.2 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 KFQ97840.1 - 0.00014 21.0 0.2 0.18 10.8 0.0 2.8 2 1 1 3 3 3 2 Squalene epoxidase 3HCDH_N PF02737.18 KFQ97840.1 - 0.0022 17.9 0.1 0.0036 17.2 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KFQ97840.1 - 0.0057 17.2 0.2 0.011 16.3 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFQ97840.1 - 0.0086 15.3 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KFQ97840.1 - 0.055 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KFQ97840.1 - 0.12 11.4 0.2 0.18 10.9 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 KFQ97840.1 - 0.19 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ATP-synt_I PF03899.15 KFQ97840.1 - 0.24 11.8 0.8 0.78 10.1 0.1 2.0 2 0 0 2 2 2 0 ATP synthase I chain Integrin_beta PF00362.18 KFQ97841.1 - 5.2e-116 386.6 0.0 7.5e-116 386.1 0.0 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_b_cyt PF08725.11 KFQ97841.1 - 6.6e-21 73.7 1.2 1.4e-20 72.7 1.2 1.6 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.12 KFQ97841.1 - 3.7e-17 62.6 5.0 3.7e-17 62.6 5.0 4.8 2 1 3 5 5 5 1 Integrin beta tail domain PSI_integrin PF17205.3 KFQ97841.1 - 1.6e-14 53.3 6.5 1.6e-14 53.3 6.5 4.4 5 0 0 5 5 5 1 Integrin plexin domain I-EGF_1 PF18372.1 KFQ97841.1 - 7.5e-08 32.3 12.7 7.5e-08 32.3 12.7 6.5 8 0 0 8 8 8 2 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 KFQ97841.1 - 0.0016 18.8 107.4 0.013 15.8 15.8 7.2 6 1 1 7 7 7 4 EGF-like domain SLX9 PF15341.6 KFQ97842.1 - 4.9e-15 56.1 7.9 5.7e-15 55.9 7.9 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 IFT46_B_C PF12317.8 KFQ97842.1 - 0.034 13.9 0.5 0.04 13.7 0.5 1.1 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal GutM PF06923.11 KFQ97842.1 - 0.043 13.9 0.1 0.061 13.4 0.1 1.2 1 0 0 1 1 1 0 Glucitol operon activator protein (GutM) MAGP PF05507.11 KFQ97842.1 - 0.044 14.2 0.1 0.05 14.0 0.1 1.1 1 0 0 1 1 1 0 Microfibril-associated glycoprotein (MAGP) A_deamin PF02137.18 KFQ97843.1 - 5.2e-117 391.0 0.0 6.8e-117 390.6 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.26 KFQ97843.1 - 3e-27 95.1 0.2 2.3e-13 50.6 0.1 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KFQ97843.1 - 0.044 14.0 2.5 2.1 8.7 0.2 3.2 2 2 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 HEAT PF02985.22 KFQ97844.1 - 0.027 14.7 3.6 0.68 10.4 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat Cnd1 PF12717.7 KFQ97844.1 - 0.04 14.0 0.1 0.11 12.6 0.1 1.5 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Peptidase_M60 PF13402.6 KFQ97846.1 - 5.6e-77 258.9 0.9 7.4e-77 258.5 0.9 1.2 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like M60-like_N PF17291.2 KFQ97846.1 - 3.1e-25 88.2 0.0 7.9e-25 86.9 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases LBP_M PF17385.2 KFQ97846.1 - 0.0048 16.4 0.0 0.89 9.0 0.0 3.1 3 0 0 3 3 3 2 Lacto-N-biose phosphorylase central domain FKBP_C PF00254.28 KFQ97847.1 - 2e-49 165.8 0.0 1.9e-31 108.2 0.0 2.3 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 KFQ97847.1 - 6.1e-18 63.8 9.2 3.7e-09 36.0 1.6 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ97847.1 - 7.3e-15 53.8 11.0 4e-06 26.5 1.1 4.3 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFQ97847.1 - 1e-08 35.2 0.9 0.0046 17.5 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ97847.1 - 8.5e-07 29.2 2.5 2.2e-05 24.7 1.2 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ97847.1 - 1.4e-06 28.0 10.2 0.00092 19.2 0.8 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ97847.1 - 1.3e-05 24.8 5.5 0.0018 17.9 0.1 3.3 2 1 1 3 3 3 2 TPR repeat TPR_19 PF14559.6 KFQ97847.1 - 1.9e-05 25.1 3.6 0.0098 16.4 2.3 2.8 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ97847.1 - 3.1e-05 24.5 0.5 0.28 11.8 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat PknG_TPR PF16918.5 KFQ97847.1 - 0.00016 20.6 0.6 0.00023 20.0 0.6 1.2 1 0 0 1 1 1 1 Protein kinase G tetratricopeptide repeat TPR_7 PF13176.6 KFQ97847.1 - 0.00016 21.4 4.1 0.022 14.7 0.3 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFQ97847.1 - 0.00038 20.5 0.2 0.00038 20.5 0.2 3.2 3 1 1 4 4 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 KFQ97847.1 - 0.00056 20.0 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ97847.1 - 0.0012 19.5 0.1 0.28 12.1 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF3856 PF12968.7 KFQ97847.1 - 0.0039 17.2 0.3 0.011 15.8 0.3 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_17 PF13431.6 KFQ97847.1 - 0.01 16.1 4.6 0.39 11.2 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ97847.1 - 0.026 14.8 8.0 10 6.5 5.5 3.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 M20_dimer PF07687.14 KFQ97847.1 - 0.091 12.7 0.0 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 Peptidase dimerisation domain Alkyl_sulf_dimr PF14863.6 KFQ97847.1 - 0.54 10.7 4.1 9.1 6.7 0.1 2.8 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation TPR_21 PF09976.9 KFQ97847.1 - 0.94 9.1 8.0 0.26 11.0 2.9 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain Itfg2 PF15907.5 KFQ97848.1 - 3.8e-165 548.8 0.0 4.5e-165 548.6 0.0 1.0 1 0 0 1 1 1 1 Integrin-alpha FG-GAP repeat-containing protein 2 BBS2_Mid PF14783.6 KFQ97848.1 - 1.3e-11 44.5 0.3 0.0025 17.9 0.0 3.4 3 0 0 3 3 3 3 Ciliary BBSome complex subunit 2, middle region VCBS PF13517.6 KFQ97848.1 - 0.00043 20.8 0.9 0.24 12.0 0.1 3.6 3 0 0 3 3 3 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BBS2_C PF14782.6 KFQ97848.1 - 0.064 12.0 0.0 8.5 5.0 0.0 2.9 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, C-terminal PHTB1_N PF14727.6 KFQ97848.1 - 0.098 12.0 0.0 3.3 7.0 0.0 2.7 3 1 1 4 4 4 0 PTHB1 N-terminus FG-GAP PF01839.23 KFQ97848.1 - 0.31 11.2 1.1 1.3 9.2 0.1 2.5 3 0 0 3 3 3 0 FG-GAP repeat Asp_protease PF09668.10 KFQ97849.1 - 2.3e-09 37.1 0.1 3.4e-09 36.5 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFQ97849.1 - 0.0044 17.6 0.0 0.0095 16.5 0.0 1.5 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RHINO PF15319.6 KFQ97850.1 - 4.2e-85 285.7 11.8 4.7e-85 285.6 11.8 1.0 1 0 0 1 1 1 1 RAD9, RAD1, HUS1-interacting nuclear orphan protein Tub PF01167.18 KFQ97851.1 - 1.7e-94 316.1 0.0 2.2e-94 315.7 0.0 1.2 1 0 0 1 1 1 1 Tub family Tub_N PF16322.5 KFQ97851.1 - 7.4e-53 180.1 7.3 1e-52 179.6 7.3 1.2 1 0 0 1 1 1 1 Tubby N-terminal DUF3527 PF12043.8 KFQ97851.1 - 0.094 12.3 0.0 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) YBD PF17725.1 KFQ97852.1 - 3.9e-95 317.6 1.6 5e-95 317.2 1.6 1.1 1 0 0 1 1 1 1 YAP binding domain TEA PF01285.18 KFQ97852.1 - 2e-27 95.0 0.0 4.4e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 TEA/ATTS domain MSP1a PF11670.8 KFQ97852.1 - 0.29 10.4 1.0 0.47 9.7 1.0 1.2 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) Tetraspanin PF00335.20 KFQ97853.1 - 7e-49 166.6 13.5 7.7e-49 166.5 13.5 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2207 PF09972.9 KFQ97853.1 - 0.062 12.1 5.8 0.14 10.9 3.3 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) OppC_N PF12911.7 KFQ97853.1 - 0.066 13.2 2.5 1.3 9.0 1.2 2.6 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C TadF PF16964.5 KFQ97853.1 - 0.074 12.8 0.4 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 Putative tight adherence pilin protein F DUF4834 PF16118.5 KFQ97853.1 - 0.11 13.4 2.8 8.1 7.5 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Baculo_11_kDa PF06143.11 KFQ97853.1 - 0.4 10.3 3.4 0.25 11.0 0.8 1.9 2 0 0 2 2 2 0 Baculovirus 11 kDa family Sigma_reg_N PF13800.6 KFQ97853.1 - 4.5 7.6 6.2 0.67 10.3 1.4 2.1 2 1 0 2 2 2 0 Sigma factor regulator N-terminal CAAP1 PF15335.6 KFQ97857.1 - 6.4e-29 100.3 9.4 1.1e-28 99.6 9.4 1.4 1 0 0 1 1 1 1 Caspase activity and apoptosis inhibitor 1 PUL PF08324.11 KFQ97858.1 - 2.4e-64 217.3 4.3 3.3e-64 216.8 4.3 1.1 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 KFQ97858.1 - 8.7e-40 135.5 0.2 1.5e-39 134.8 0.2 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 KFQ97858.1 - 3.2e-35 119.6 8.2 7.4e-06 26.6 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat BBS2_Mid PF14783.6 KFQ97858.1 - 0.0017 18.4 0.0 2.3 8.3 0.0 3.1 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 KFQ97858.1 - 0.0028 17.0 0.0 1.1 8.6 0.0 2.6 1 1 1 2 2 2 2 WD40-like domain Rnk_N PF14760.6 KFQ97858.1 - 0.32 11.5 1.5 1.7 9.2 0.1 2.3 2 0 0 2 2 2 0 Rnk N-terminus Mob1_phocein PF03637.17 KFQ97859.1 - 1.7e-81 272.2 0.2 2e-81 272.0 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family C9orf72-like PF15019.6 KFQ97860.1 - 1.5e-96 322.7 0.0 2.2e-96 322.1 0.0 1.3 1 0 0 1 1 1 1 C9orf72-like protein family Pkinase_Tyr PF07714.17 KFQ97870.1 - 1.8e-134 447.0 0.0 1e-79 267.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFQ97870.1 - 1.2e-73 247.8 0.0 2.8e-49 167.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain FERM_F2 PF18377.1 KFQ97870.1 - 7e-38 129.5 0.0 1.6e-37 128.4 0.0 1.7 1 0 0 1 1 1 1 FERM F2 acyl-CoA binding protein-like domain FERM_F1 PF18379.1 KFQ97870.1 - 8.2e-33 112.3 0.0 2.6e-32 110.7 0.0 1.9 1 0 0 1 1 1 1 FERM F1 ubiquitin-like domain Jak1_Phl PF17887.1 KFQ97870.1 - 5.9e-16 58.7 0.0 2.9e-15 56.5 0.0 2.2 1 1 1 2 2 2 1 Jak1 pleckstrin homology-like domain SH2 PF00017.24 KFQ97870.1 - 2.6e-05 24.2 0.0 7.6e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Kinase-like PF14531.6 KFQ97870.1 - 0.00043 19.7 0.0 0.68 9.2 0.0 2.5 2 1 0 2 2 2 2 Kinase-like APH PF01636.23 KFQ97870.1 - 0.033 14.1 0.1 0.12 12.2 0.1 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFQ97870.1 - 0.057 12.4 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Ccdc124 PF06244.12 KFQ97871.1 - 2.1e-42 144.7 9.2 2.1e-42 144.7 9.2 2.4 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 KFQ97871.1 - 0.0021 18.5 0.8 0.0021 18.5 0.8 2.8 2 1 1 3 3 3 1 HMG (high mobility group) box UPF0240 PF06784.11 KFQ97871.1 - 0.2 11.7 12.5 0.037 14.1 8.9 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) Asp-B-Hydro_N PF05279.11 KFQ97871.1 - 2.3 8.2 23.0 2.7 8.0 23.0 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TMEM214 PF10151.9 KFQ97871.1 - 5.6 5.3 12.1 6.6 5.1 12.1 1.4 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator SK_channel PF03530.14 KFQ97872.1 - 4.1e-29 100.9 0.5 4.1e-29 100.9 0.5 2.4 2 0 0 2 2 2 1 Calcium-activated SK potassium channel CaMBD PF02888.16 KFQ97872.1 - 5.2e-24 84.2 5.6 1e-23 83.3 5.6 1.5 1 0 0 1 1 1 1 Calmodulin binding domain Ion_trans_2 PF07885.16 KFQ97872.1 - 2e-13 50.1 3.5 2e-13 50.1 3.5 2.0 2 0 0 2 2 2 1 Ion channel PMP1_2 PF08114.11 KFQ97872.1 - 0.28 10.9 4.9 4.7 7.0 0.2 2.7 2 0 0 2 2 2 0 ATPase proteolipid family IRK PF01007.20 KFQ97872.1 - 0.32 10.8 5.2 0.17 11.7 2.6 1.9 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain MARVEL PF01284.23 KFQ97873.1 - 2.6e-29 102.1 13.0 3.6e-29 101.6 13.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain Occludin_ELL PF07303.13 KFQ97873.1 - 2.9e-28 98.5 5.9 4.3e-28 98.0 5.9 1.3 1 0 0 1 1 1 1 Occludin homology domain T3SSipB PF16535.5 KFQ97873.1 - 0.028 14.9 1.0 0.043 14.3 1.0 1.2 1 0 0 1 1 1 0 Type III cell invasion protein SipB DASH_Dad1 PF08649.10 KFQ97873.1 - 0.057 13.6 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad1 NPV_P10 PF05531.12 KFQ97873.1 - 0.13 12.7 0.5 3.2 8.3 0.1 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein BRE1 PF08647.11 KFQ97873.1 - 0.18 11.9 1.3 0.32 11.1 1.3 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF2417 PF10329.9 KFQ97873.1 - 0.91 8.9 5.1 1.7 8.0 5.1 1.4 1 0 0 1 1 1 0 Region of unknown function (DUF2417) DctQ PF04290.12 KFQ97873.1 - 4 7.4 11.0 1.4 8.9 0.1 2.8 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Abhydrolase_1 PF00561.20 KFQ97874.1 - 7.8e-24 84.7 0.1 4.2e-18 65.9 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFQ97874.1 - 8.3e-17 61.2 0.7 1.5e-15 57.1 0.7 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFQ97874.1 - 4.8e-15 56.8 0.1 9.6e-15 55.8 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KFQ97874.1 - 0.00022 21.1 0.3 0.52 10.1 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase DUF2920 PF11144.8 KFQ97874.1 - 0.0055 15.9 0.0 0.18 11.0 0.0 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2920) UBA_6 PF18039.1 KFQ97874.1 - 0.011 15.7 0.2 0.038 13.9 0.1 2.0 2 0 0 2 2 2 0 UBA-like domain FSH1 PF03959.13 KFQ97874.1 - 0.013 15.2 0.0 0.035 13.8 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KFQ97874.1 - 0.024 14.1 0.1 0.19 11.2 0.0 2.2 2 1 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 KFQ97874.1 - 0.039 14.1 0.0 0.093 12.9 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein DLH PF01738.18 KFQ97874.1 - 0.044 13.3 0.0 8.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Ndr PF03096.14 KFQ97874.1 - 0.073 11.8 0.0 1.1 7.9 0.0 2.0 2 0 0 2 2 2 0 Ndr family Ser_hydrolase PF06821.13 KFQ97874.1 - 0.09 12.6 0.0 13 5.6 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase BAAT_C PF08840.11 KFQ97874.1 - 0.14 12.0 0.0 1.2 9.0 0.0 2.4 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal VirJ PF06057.11 KFQ97874.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_8 PF06259.12 KFQ97874.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase LIP PF03583.14 KFQ97874.1 - 0.15 11.3 0.0 0.44 9.8 0.0 1.7 1 1 1 2 2 2 0 Secretory lipase Ribosomal_L34 PF00468.17 KFQ97875.1 - 1.1e-19 70.1 2.0 1.4e-19 69.7 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L34 DDA1 PF10172.9 KFQ97876.1 - 1.8e-30 105.0 0.1 2.7e-30 104.4 0.1 1.3 1 0 0 1 1 1 1 Det1 complexing ubiquitin ligase Ig_3 PF13927.6 KFQ97877.1 - 3.7e-12 46.7 0.1 1.8e-11 44.5 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain CarboxypepD_reg PF13620.6 KFQ97877.1 - 9.9e-11 41.8 1.2 1.5e-05 25.1 0.1 3.0 2 0 0 2 2 2 2 Carboxypeptidase regulatory-like domain Ig_2 PF13895.6 KFQ97877.1 - 3.3e-09 36.9 0.2 7.9e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin domain CarbopepD_reg_2 PF13715.6 KFQ97877.1 - 1.1e-07 31.7 0.0 0.00012 22.0 0.0 2.5 2 0 0 2 2 2 2 CarboxypepD_reg-like domain I-set PF07679.16 KFQ97877.1 - 3.5e-06 27.0 0.0 4.5e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 KFQ97877.1 - 0.0023 18.1 0.0 0.0096 16.1 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFQ97877.1 - 0.18 12.0 0.0 3.5 7.8 0.0 2.8 2 1 1 3 3 3 0 Immunoglobulin V-set domain YjeF_N PF03853.15 KFQ97878.1 - 3.6e-28 98.6 0.0 4.3e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Cohesin_load PF10345.9 KFQ97879.1 - 4.2e-110 369.0 13.1 5.1e-110 368.7 13.1 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.6 KFQ97879.1 - 1.8e-08 34.5 9.3 0.0016 18.7 0.1 4.8 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ97879.1 - 1.7e-07 30.8 5.4 0.22 11.7 0.2 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFQ97879.1 - 3.3e-06 26.7 14.3 0.00046 19.7 2.2 3.7 2 1 2 4 4 4 2 MalT-like TPR region TPR_8 PF13181.6 KFQ97879.1 - 9.8e-05 22.3 5.8 1.3 9.4 0.1 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ97879.1 - 0.00089 19.1 0.1 3.6 7.6 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ97879.1 - 0.0028 17.4 5.1 1.7 8.6 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat HemY_N PF07219.13 KFQ97879.1 - 0.0036 17.5 0.0 0.083 13.1 0.0 2.7 2 0 0 2 2 2 1 HemY protein N-terminus TPR_19 PF14559.6 KFQ97879.1 - 0.065 13.8 4.7 1.8 9.1 0.1 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ97879.1 - 0.092 12.4 0.1 6.4 6.5 0.0 3.3 3 0 0 3 3 3 0 TPR repeat DUF4110 PF13422.6 KFQ97879.1 - 0.12 12.5 0.0 20 5.3 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4110) ANAPC3 PF12895.7 KFQ97879.1 - 0.76 10.0 8.6 6 7.2 0.6 4.1 3 2 2 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Surp PF01805.20 KFQ97880.1 - 1.8e-28 98.3 3.3 2.7e-15 56.1 0.1 2.8 2 0 0 2 2 2 2 Surp module G-patch PF01585.23 KFQ97880.1 - 3.2e-15 55.7 2.8 8.5e-15 54.4 2.8 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFQ97880.1 - 3.7e-07 30.1 1.7 4.3e-06 26.7 0.4 2.9 2 0 0 2 2 2 1 G-patch domain RtcB PF01139.17 KFQ97880.1 - 0.016 14.4 0.3 0.03 13.5 0.3 1.4 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB Tuberculin PF12198.8 KFQ97880.1 - 0.046 13.8 0.0 5.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Theoretical tuberculin protein DUF3439 PF11921.8 KFQ97880.1 - 7.5 6.5 8.0 19 5.2 8.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF2781 PF10914.8 KFQ97881.1 - 1e-22 81.2 16.4 9.2e-22 78.0 7.6 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2781) MFS_1_like PF12832.7 KFQ97881.1 - 0.0096 14.8 0.3 0.014 14.2 0.3 1.4 1 0 0 1 1 1 1 MFS_1 like family F5_F8_type_C PF00754.25 KFQ97882.1 - 0.0013 18.9 0.0 0.0023 18.1 0.0 1.3 1 1 0 1 1 1 1 F5/8 type C domain ApeA_NTD1 PF18862.1 KFQ97882.1 - 0.0051 16.4 0.1 0.0067 16.0 0.1 1.1 1 0 0 1 1 1 1 ApeA N-terminal domain 1 ANAPC10 PF03256.16 KFQ97882.1 - 0.14 11.8 0.1 0.19 11.3 0.1 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) F_actin_bund_C PF18060.1 KFQ97883.1 - 0.051 13.7 0.1 0.058 13.5 0.1 1.0 1 0 0 1 1 1 0 F actin bundling C terminal BORCS8 PF10167.9 KFQ97884.1 - 3.4e-17 62.4 0.1 3.6e-17 62.3 0.1 1.0 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 8 SRF-TF PF00319.18 KFQ97885.1 - 8.5e-24 82.8 0.3 1.4e-23 82.1 0.3 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) GHD PF17834.1 KFQ97885.1 - 0.1 12.6 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Beta-sandwich domain in beta galactosidase Tmemb_161AB PF10268.9 KFQ97886.1 - 1.7e-193 643.6 0.4 2e-193 643.4 0.4 1.0 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB Arm PF00514.23 KFQ97887.1 - 4.7e-09 36.0 2.6 0.085 12.9 0.0 5.5 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 KFQ97887.1 - 0.00062 19.7 6.5 0.14 12.2 0.2 4.7 3 1 3 6 6 6 2 Spinocerebellar ataxia type 10 protein domain UBA_3 PF09288.10 KFQ97887.1 - 0.045 13.6 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain UNC45-central PF11701.8 KFQ97887.1 - 0.068 13.1 0.8 0.27 11.2 0.0 2.5 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central Mis14 PF08641.12 KFQ97887.1 - 0.31 11.4 2.5 0.6 10.4 2.5 1.4 1 0 0 1 1 1 0 Kinetochore protein Mis14 like Surp PF01805.20 KFQ97888.1 - 5.4e-15 55.1 1.8 8.3e-10 38.5 0.1 2.6 2 0 0 2 2 2 2 Surp module G-patch PF01585.23 KFQ97888.1 - 2.9e-14 52.7 4.2 5.2e-14 51.9 4.2 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFQ97888.1 - 0.0018 18.4 2.7 0.0049 16.9 2.7 1.8 1 0 0 1 1 1 1 G-patch domain Nop14 PF04147.12 KFQ97888.1 - 0.075 11.2 12.3 0.14 10.4 12.3 1.3 1 0 0 1 1 1 0 Nop14-like family DUF2591 PF10765.9 KFQ97888.1 - 0.28 11.5 0.7 0.73 10.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2591) CDC45 PF02724.14 KFQ97888.1 - 0.35 9.1 5.4 0.59 8.4 5.4 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF4637 PF15470.6 KFQ97888.1 - 4.6 6.9 12.3 13 5.4 12.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Sema PF01403.19 KFQ97889.1 - 4.7e-148 493.5 1.7 5e-147 490.1 0.0 2.0 1 1 1 2 2 2 1 Sema domain PSI PF01437.25 KFQ97889.1 - 2.6e-07 31.1 3.2 7.2e-07 29.6 3.2 1.8 1 0 0 1 1 1 1 Plexin repeat DUF824 PF05688.11 KFQ97889.1 - 0.03 14.1 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) Ig_3 PF13927.6 KFQ97889.1 - 0.042 14.4 0.0 0.13 12.9 0.0 1.9 1 0 0 1 1 1 0 Immunoglobulin domain ig PF00047.25 KFQ97889.1 - 0.064 13.4 0.0 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 Immunoglobulin domain Ig_2 PF13895.6 KFQ97889.1 - 0.093 13.1 0.1 0.27 11.6 0.1 1.8 1 0 0 1 1 1 0 Immunoglobulin domain Thioredoxin_5 PF13743.6 KFQ97889.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin PSI_integrin PF17205.3 KFQ97889.1 - 0.23 11.2 2.3 0.73 9.6 2.3 1.9 1 0 0 1 1 1 0 Integrin plexin domain WH1 PF00568.23 KFQ97890.1 - 9.4e-37 125.4 0.2 1.8e-36 124.5 0.2 1.5 1 0 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 KFQ97890.1 - 0.15 12.3 2.0 3.5 7.9 0.1 2.4 2 0 0 2 2 2 0 VID27 PH-like domain DUF3461 PF11944.8 KFQ97890.1 - 0.63 10.2 13.6 0.03 14.5 3.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) GAS PF13851.6 KFQ97890.1 - 0.71 9.2 34.5 3.4 7.0 27.6 2.9 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Flu_M1_C PF08289.11 KFQ97890.1 - 1.1 9.5 4.9 0.67 10.2 1.0 2.6 2 1 1 3 3 3 0 Influenza Matrix protein (M1) C-terminal domain PKcGMP_CC PF16808.5 KFQ97890.1 - 2.3 8.2 13.0 0.099 12.5 2.3 3.6 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Laminin_II PF06009.12 KFQ97890.1 - 6.8 6.7 14.9 1.6 8.7 4.9 3.2 3 0 0 3 3 3 0 Laminin Domain II DEAD PF00270.29 KFQ97891.1 - 6.7e-42 143.2 0.4 1.4e-41 142.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFQ97891.1 - 2.5e-27 95.4 0.1 2.5e-27 95.4 0.1 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 KFQ97891.1 - 0.0011 19.3 0.1 0.51 10.7 0.0 2.5 1 1 1 2 2 2 2 AAA domain SWI2_SNF2 PF18766.1 KFQ97891.1 - 0.0049 16.6 0.2 0.071 12.8 0.0 2.3 2 1 0 2 2 2 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 KFQ97891.1 - 0.099 12.9 2.5 0.44 10.8 0.2 2.9 2 1 0 2 2 2 0 AAA domain Coatomer_E PF04733.14 KFQ97892.1 - 5.2e-114 380.5 5.5 5.8e-114 380.4 5.5 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 KFQ97892.1 - 2.7e-10 40.6 7.4 3.2e-05 24.4 0.2 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ97892.1 - 4.3e-09 36.4 4.8 0.015 16.1 0.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ97892.1 - 3.2e-08 33.7 1.1 0.0061 16.8 0.2 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KFQ97892.1 - 9.8e-07 28.4 3.3 0.0009 19.2 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ97892.1 - 7.2e-06 26.2 1.3 0.0046 17.2 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ97892.1 - 4.4e-05 24.0 1.1 0.0043 17.7 0.0 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ97892.1 - 0.00036 20.3 1.1 0.0052 16.7 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ97892.1 - 0.001 18.8 4.0 0.0074 16.1 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat CysG_dimeriser PF10414.9 KFQ97892.1 - 0.04 13.6 0.1 0.093 12.5 0.1 1.6 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region HemY_N PF07219.13 KFQ97892.1 - 0.052 13.7 0.6 6.2 7.1 0.2 2.6 2 0 0 2 2 2 0 HemY protein N-terminus PPR PF01535.20 KFQ97892.1 - 0.07 13.4 2.7 14 6.2 0.0 3.8 4 0 0 4 4 4 0 PPR repeat Com_YlbF PF06133.11 KFQ97892.1 - 0.12 13.0 4.0 0.3 11.7 0.1 2.9 3 0 0 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA TPR_6 PF13174.6 KFQ97892.1 - 0.14 12.8 5.5 1.9 9.3 0.0 3.8 5 0 0 5 5 3 0 Tetratricopeptide repeat TRAM_LAG1_CLN8 PF03798.16 KFQ97893.1 - 4.1e-37 127.8 26.9 4.8e-37 127.6 26.9 1.0 1 0 0 1 1 1 1 TLC domain TGF_beta PF00019.20 KFQ97895.1 - 1e-34 119.6 0.2 2.3e-34 118.5 0.2 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFQ97895.1 - 9.4e-06 25.5 0.1 1.6e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 TGF-beta propeptide UPF1_Zn_bind PF09416.10 KFQ97896.1 - 3.6e-75 251.0 6.7 1.4e-74 249.1 6.9 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 KFQ97896.1 - 4.6e-61 205.9 0.0 8e-61 205.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFQ97896.1 - 4.4e-48 164.4 2.2 6.5e-27 95.0 0.3 2.4 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KFQ97896.1 - 2.5e-31 107.8 0.0 7.8e-31 106.2 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KFQ97896.1 - 1.3e-13 51.1 0.1 2e-12 47.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KFQ97896.1 - 1.5e-10 41.6 0.1 6.1e-10 39.6 0.0 2.0 2 1 0 2 2 1 1 AAA domain ResIII PF04851.15 KFQ97896.1 - 1.4e-05 25.2 0.0 3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KFQ97896.1 - 0.0001 21.7 0.0 0.0076 15.5 0.0 2.7 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 KFQ97896.1 - 0.00042 20.2 0.0 0.001 19.0 0.0 1.7 1 0 0 1 1 1 1 Helicase ATPase PF06745.13 KFQ97896.1 - 0.00074 18.9 0.0 0.014 14.7 0.0 2.2 2 0 0 2 2 2 1 KaiC SRP54 PF00448.22 KFQ97896.1 - 0.0051 16.5 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain UvrD-helicase PF00580.21 KFQ97896.1 - 0.017 14.6 0.1 0.85 9.1 0.0 2.7 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain PIF1 PF05970.14 KFQ97896.1 - 0.045 12.9 0.0 5 6.2 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase DEAD PF00270.29 KFQ97896.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_10 PF12846.7 KFQ97896.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain UvrD_C_2 PF13538.6 KFQ97896.1 - 0.19 11.6 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA PF00004.29 KFQ97896.1 - 0.2 12.1 0.0 0.44 11.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TSP_C PF05735.12 KFQ97897.1 - 9.9e-99 329.2 1.1 1.3e-98 328.8 1.1 1.1 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.18 KFQ97897.1 - 1.3e-54 181.5 134.7 2.9e-11 42.9 11.1 9.4 7 2 1 8 8 8 7 Thrombospondin type 3 repeat EGF_CA PF07645.15 KFQ97897.1 - 2.2e-18 66.2 42.2 4.3e-09 36.4 6.7 5.6 4 0 0 4 4 4 4 Calcium-binding EGF domain COMP PF11598.8 KFQ97897.1 - 5.7e-17 61.9 1.8 1.3e-16 60.8 1.8 1.6 1 0 0 1 1 1 1 Cartilage oligomeric matrix protein cEGF PF12662.7 KFQ97897.1 - 8.1e-11 41.6 26.8 3.6e-05 23.6 3.5 5.6 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF_3 PF12947.7 KFQ97897.1 - 1e-07 32.0 49.7 0.00015 21.9 4.1 6.0 6 0 0 6 6 6 4 EGF domain EGF_MSP1_1 PF12946.7 KFQ97897.1 - 0.0056 16.7 4.3 0.0056 16.7 4.3 4.8 5 0 0 5 5 5 2 MSP1 EGF domain 1 TORC_M PF12885.7 KFQ97898.1 - 1e-68 230.2 9.0 1e-68 230.2 9.0 2.9 3 1 1 4 4 4 1 Transducer of regulated CREB activity middle domain TORC_C PF12886.7 KFQ97898.1 - 5e-33 113.5 2.3 1.4e-32 112.1 2.3 1.8 1 0 0 1 1 1 1 Transducer of regulated CREB activity, C terminus Kelch_1 PF01344.25 KFQ97899.1 - 1.2e-36 124.1 20.2 7.1e-09 35.1 0.4 6.3 5 2 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 KFQ97899.1 - 3e-34 116.2 3.4 5.1e-06 26.6 0.0 5.5 2 1 3 5 5 5 5 Kelch motif BACK PF07707.15 KFQ97899.1 - 5.6e-26 90.6 0.7 1.1e-25 89.7 0.7 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 KFQ97899.1 - 2.6e-18 65.2 8.8 0.00015 21.6 0.1 6.2 6 1 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 KFQ97899.1 - 5.2e-18 64.8 1.8 0.0025 17.8 0.0 5.3 3 1 2 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KFQ97899.1 - 3.7e-15 55.8 0.4 0.0004 20.6 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain BTB PF00651.31 KFQ97899.1 - 3.2e-12 46.6 0.0 7e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.6 KFQ97899.1 - 6.9e-10 38.7 7.2 0.085 12.9 0.1 5.4 5 0 0 5 5 5 4 Kelch motif PQQ_3 PF13570.6 KFQ97899.1 - 0.016 15.7 0.0 25 5.5 0.1 4.1 4 0 0 4 4 4 0 PQQ-like domain BSMAP PF12280.8 KFQ97900.1 - 7.6e-19 68.7 0.0 8.2e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Brain specific membrane anchored protein DUF997 PF06196.12 KFQ97900.1 - 0.022 14.8 0.9 0.027 14.5 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF997) TrkA_TMD PF18613.1 KFQ97900.1 - 0.049 13.1 5.0 0.074 12.5 5.0 1.3 1 0 0 1 1 1 0 Tyrosine kinase receptor A trans-membrane domain Lep_receptor_Ig PF06328.11 KFQ97901.1 - 8.2e-08 32.1 0.0 4.7e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 Ig-like C2-type domain EpoR_lig-bind PF09067.10 KFQ97901.1 - 4.4e-05 23.6 0.0 7.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding IL6Ra-bind PF09240.10 KFQ97901.1 - 0.00034 21.0 0.4 0.0008 19.8 0.4 1.6 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding ig PF00047.25 KFQ97901.1 - 0.0018 18.4 0.1 0.53 10.5 0.0 2.3 2 1 0 2 2 2 2 Immunoglobulin domain ubiquitin PF00240.23 KFQ97902.1 - 6.9e-35 118.6 0.3 8.7e-35 118.3 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 KFQ97902.1 - 3.8e-23 81.1 8.0 6.2e-23 80.4 8.0 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 KFQ97902.1 - 1.2e-17 63.5 0.4 1.2e-17 63.5 0.4 1.4 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFQ97902.1 - 7.5e-06 26.3 0.1 2.8e-05 24.5 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KFQ97902.1 - 0.0017 18.5 0.0 0.0034 17.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KFQ97902.1 - 0.0017 18.3 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KFQ97902.1 - 0.0034 17.7 0.0 0.0057 17.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 KFQ97902.1 - 0.0098 15.9 0.8 2.7 8.1 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin-like domain DUF2407 PF10302.9 KFQ97902.1 - 0.035 14.7 0.1 0.039 14.5 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain KxDL PF10241.9 KFQ97903.1 - 3.1e-30 104.3 1.5 4.8e-30 103.7 1.5 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF4692 PF15763.5 KFQ97903.1 - 1.6 9.2 4.4 15 6.1 4.4 2.0 1 1 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) TPR_1 PF00515.28 KFQ97904.1 - 1.4e-15 56.3 4.6 4.9e-06 26.1 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ97904.1 - 2.7e-13 48.9 3.3 1.1e-05 25.1 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat FKBP_C PF00254.28 KFQ97904.1 - 5e-13 49.2 0.0 9.4e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Fis1_TPR_C PF14853.6 KFQ97904.1 - 1.4e-08 34.6 2.2 0.0008 19.4 0.1 2.6 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 KFQ97904.1 - 1.5e-08 34.8 0.0 2.7e-05 24.6 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ97904.1 - 7.9e-08 31.9 0.4 0.00013 21.9 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ97904.1 - 3.4e-07 29.8 1.2 5.4e-05 22.8 0.0 2.8 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.6 KFQ97904.1 - 4.2e-07 30.5 0.3 0.00056 20.5 0.1 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFQ97904.1 - 7.9e-07 29.1 0.1 5.2e-06 26.5 0.0 2.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ97904.1 - 1.3e-06 28.0 0.6 0.0062 16.5 0.0 3.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ97904.1 - 1.4e-05 25.3 0.7 0.00061 20.0 0.3 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ97904.1 - 2.6e-05 24.6 0.6 0.0074 16.8 0.1 2.5 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ97904.1 - 0.00013 22.1 0.9 0.023 15.0 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ97904.1 - 0.0002 21.5 0.7 0.0014 18.8 0.0 2.5 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 KFQ97904.1 - 0.0023 16.9 0.2 0.0033 16.4 0.2 1.2 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 KFQ97904.1 - 0.0025 17.6 0.8 1.6 8.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFQ97904.1 - 0.008 16.8 0.6 0.42 11.4 0.1 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KFQ97904.1 - 0.18 12.2 0.4 2.9 8.4 0.0 2.2 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation ELL PF10390.9 KFQ97905.1 - 5.1e-106 354.2 0.0 5.1e-106 354.2 0.0 2.4 2 1 0 2 2 2 1 RNA polymerase II elongation factor ELL Occludin_ELL PF07303.13 KFQ97905.1 - 4.4e-34 117.2 13.6 4.4e-34 117.2 13.6 3.0 3 0 0 3 3 3 1 Occludin homology domain TraV PF09676.10 KFQ97905.1 - 1.4 9.9 13.0 1.6 9.7 7.9 2.7 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Seryl_tRNA_N PF02403.22 KFQ97905.1 - 6.5 7.0 14.1 0.78 10.0 2.3 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain NAD_binding_5 PF07994.12 KFQ97906.1 - 5.6e-146 486.0 0.0 6.7e-146 485.7 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KFQ97906.1 - 1.9e-48 163.2 0.1 3.7e-48 162.3 0.1 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Ank_2 PF12796.7 KFQ97910.1 - 4.9e-43 145.6 3.3 3.2e-10 40.5 0.1 4.6 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ97910.1 - 2.4e-35 120.5 6.3 8.6e-09 35.8 0.0 6.9 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 KFQ97910.1 - 1.1e-29 101.5 7.2 2.4e-05 24.5 0.0 8.5 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 KFQ97910.1 - 8.9e-29 99.2 6.0 2.8e-07 30.7 0.0 6.3 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ97910.1 - 2e-28 95.3 2.1 0.00068 19.9 0.0 8.7 9 0 0 9 9 9 6 Ankyrin repeat fn3 PF00041.21 KFQ97911.1 - 2e-32 111.4 9.3 3.3e-09 37.0 0.3 5.6 5 0 0 5 5 5 4 Fibronectin type III domain Lep_receptor_Ig PF06328.11 KFQ97911.1 - 2.6e-29 101.0 0.3 7.5e-29 99.5 0.3 1.9 1 0 0 1 1 1 1 Ig-like C2-type domain EpoR_lig-bind PF09067.10 KFQ97911.1 - 2.3e-05 24.5 0.0 5.3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding fn3_2 PF16893.5 KFQ97911.1 - 0.00024 21.2 0.1 0.0087 16.2 0.0 2.8 2 0 0 2 2 2 1 Fibronectin type III domain IL6Ra-bind PF09240.10 KFQ97911.1 - 0.00037 20.9 0.9 0.0011 19.4 0.1 2.2 2 0 0 2 2 2 1 Interleukin-6 receptor alpha chain, binding ObR_Ig PF18589.1 KFQ97911.1 - 0.03 14.7 0.0 1 9.8 0.0 2.7 1 1 0 1 1 1 0 Obesity receptor immunoglobulin like domain Pur_ac_phosph_N PF16656.5 KFQ97911.1 - 0.1 13.1 12.9 0.34 11.5 0.0 3.9 4 1 0 4 4 4 0 Purple acid Phosphatase, N-terminal domain DUF3377 PF11857.8 KFQ97911.1 - 0.21 11.5 0.3 0.49 10.3 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) fn3 PF00041.21 KFQ97912.1 - 1e-25 89.9 4.8 3.6e-09 36.8 0.1 4.1 4 0 0 4 4 4 3 Fibronectin type III domain DUF4998 PF16389.5 KFQ97912.1 - 0.0014 18.3 0.6 0.81 9.2 0.1 3.1 3 0 0 3 3 3 2 Domain of unknown function Big_5 PF13205.6 KFQ97912.1 - 0.002 18.8 2.7 0.021 15.5 0.2 2.5 2 0 0 2 2 2 1 Bacterial Ig-like domain Pur_ac_phosph_N PF16656.5 KFQ97912.1 - 0.0084 16.7 10.7 5.8 7.6 0.0 3.7 2 1 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Glyco_hydro_36C PF16874.5 KFQ97912.1 - 0.14 12.7 0.0 0.7 10.4 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 36 C-terminal domain DEAD PF00270.29 KFQ97913.1 - 1.6e-49 168.0 0.0 2.9e-49 167.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFQ97913.1 - 8.4e-32 109.8 0.2 8.7e-31 106.5 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFQ97913.1 - 0.0055 16.7 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KFQ97913.1 - 0.12 11.1 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 PAP2 PF01569.21 KFQ97914.1 - 2.2e-28 98.7 1.6 2.2e-28 98.7 1.6 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KFQ97914.1 - 0.0044 17.5 2.0 0.0044 17.5 2.0 2.5 2 1 1 3 3 3 1 PAP2 superfamily C-terminal COX4 PF02936.14 KFQ97914.1 - 0.0064 16.5 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV TPPK_C PF12555.8 KFQ97914.1 - 0.14 12.2 1.2 19 5.4 0.2 2.6 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal DUF4231 PF14015.6 KFQ97914.1 - 1.3 9.5 4.4 2.7 8.5 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) rRNA_proc-arch PF13234.6 KFQ97915.1 - 1.2e-87 294.3 1.8 2.1e-87 293.5 1.8 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 KFQ97915.1 - 5.4e-59 198.5 0.8 1.1e-58 197.5 0.8 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KFQ97915.1 - 9.7e-17 61.3 0.0 2.6e-16 59.9 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFQ97915.1 - 1.7e-07 31.6 0.0 1.7e-06 28.3 0.0 2.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFQ97915.1 - 0.025 14.9 0.0 0.17 12.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain DUF3379 PF11859.8 KFQ97915.1 - 0.047 13.0 0.1 0.18 11.1 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) AAA_19 PF13245.6 KFQ97915.1 - 0.05 13.9 0.1 0.23 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain UCH_1 PF13423.6 KFQ97916.1 - 2.9e-104 349.1 0.2 3.9e-104 348.7 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 KFQ97916.1 - 4.7e-08 32.8 0.8 7.7e-06 25.6 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase WD40_like PF17005.5 KFQ97916.1 - 6.8e-05 22.3 0.2 0.00012 21.5 0.2 1.3 1 0 0 1 1 1 1 WD40-like domain DUF3456 PF11938.8 KFQ97917.1 - 3.4e-39 134.9 0.6 4.2e-39 134.6 0.6 1.1 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP DUF3150 PF11348.8 KFQ97917.1 - 0.01 15.1 0.0 0.56 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3150) SapB_2 PF03489.17 KFQ97917.1 - 0.02 15.0 0.0 0.1 12.7 0.0 2.2 2 0 0 2 2 2 0 Saposin-like type B, region 2 Citrate_synt PF00285.21 KFQ97918.1 - 1.4e-105 353.3 0.0 1.7e-105 353.1 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Queuosine_synth PF02547.15 KFQ97918.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein PAS_3 PF08447.12 KFQ97918.1 - 0.11 12.9 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 PAS fold Polyketide_cyc PF03364.20 KFQ97919.1 - 1.5e-26 93.1 0.2 1.8e-26 92.9 0.2 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Ank_2 PF12796.7 KFQ97920.1 - 9.9e-192 622.1 91.7 3.5e-19 69.2 0.1 14.3 1 1 16 17 17 17 17 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ97920.1 - 7.9e-149 482.3 49.5 9.2e-14 51.6 0.1 19.3 9 4 12 21 21 21 20 Ankyrin repeats (many copies) Ank PF00023.30 KFQ97920.1 - 5.5e-125 402.9 77.6 2.7e-06 27.5 0.2 27.4 27 0 0 27 27 27 27 Ankyrin repeat Ank_3 PF13606.6 KFQ97920.1 - 6.8e-117 367.1 54.5 6.1e-05 23.1 0.1 28.0 28 0 0 28 28 28 25 Ankyrin repeat Ank_5 PF13857.6 KFQ97920.1 - 1.3e-109 356.8 57.8 6.6e-10 39.0 0.1 21.8 6 5 15 22 22 22 21 Ankyrin repeats (many copies) GATase_7 PF13537.6 KFQ97920.1 - 0.0019 18.1 0.0 30 4.5 0.0 6.1 6 0 0 6 6 6 0 Glutamine amidotransferase domain PEGA PF08308.11 KFQ97920.1 - 0.019 14.8 0.0 26 4.8 0.0 4.9 4 0 0 4 4 4 0 PEGA domain USP8_interact PF08941.10 KFQ97921.1 - 2.1e-14 53.7 4.4 3.6e-14 53.0 4.4 1.4 1 0 0 1 1 1 1 USP8 interacting Sina PF03145.16 KFQ97921.1 - 3.5e-06 27.1 2.5 4.8e-06 26.7 2.5 1.2 1 0 0 1 1 1 1 Seven in absentia protein family zf-rbx1 PF12678.7 KFQ97921.1 - 4.2e-06 27.0 5.4 4.2e-06 27.0 5.4 2.6 2 1 1 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFQ97921.1 - 2.6e-05 24.0 3.7 2.6e-05 24.0 3.7 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ97921.1 - 2.7e-05 24.4 4.6 2.7e-05 24.4 4.6 2.4 3 1 1 4 4 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFQ97921.1 - 0.00012 21.8 5.6 0.00012 21.8 5.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 KFQ97921.1 - 0.00023 21.8 3.7 0.036 14.8 2.0 2.7 1 1 1 2 2 2 1 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 KFQ97921.1 - 0.00027 20.8 1.4 0.00027 20.8 1.4 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Trimer_CC PF08954.11 KFQ97921.1 - 0.00081 18.9 0.4 0.0037 16.8 0.2 2.1 2 0 0 2 2 2 1 Trimerisation motif zf-RING_5 PF14634.6 KFQ97921.1 - 0.0013 18.7 3.6 0.0013 18.7 3.6 2.2 3 0 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFQ97921.1 - 0.0057 16.5 2.1 0.017 15.0 2.1 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFQ97921.1 - 0.0063 16.5 2.2 0.016 15.2 2.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger BLOC1_2 PF10046.9 KFQ97921.1 - 0.018 15.4 3.1 0.038 14.3 3.1 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF641 PF04859.12 KFQ97921.1 - 0.019 15.3 0.6 0.033 14.5 0.6 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) zf-RING_UBOX PF13445.6 KFQ97921.1 - 0.021 14.9 4.7 0.021 14.9 4.7 2.2 3 0 0 3 3 2 0 RING-type zinc-finger zf-RING_6 PF14835.6 KFQ97921.1 - 0.023 14.5 0.1 0.023 14.5 0.1 2.0 2 1 1 3 3 2 0 zf-RING of BARD1-type protein Atx10homo_assoc PF09759.9 KFQ97921.1 - 0.045 13.8 2.0 0.61 10.1 0.4 2.2 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain zf-C3HC4_4 PF15227.6 KFQ97921.1 - 0.047 13.8 3.4 0.047 13.8 3.4 2.4 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-CCCH_6 PF18585.1 KFQ97921.1 - 0.082 12.8 2.5 0.17 11.8 0.1 2.6 3 0 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 SlyX PF04102.12 KFQ97921.1 - 0.083 13.5 5.5 0.25 12.0 5.4 1.9 1 1 0 1 1 1 0 SlyX zf-TRAF_2 PF15965.5 KFQ97921.1 - 0.087 13.3 11.7 0.11 13.0 7.9 2.4 1 1 1 2 2 2 0 TRAF-like zinc-finger DUF1754 PF08555.10 KFQ97921.1 - 0.12 13.2 0.3 0.16 12.8 0.3 1.2 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Zn_ribbon_17 PF17120.5 KFQ97921.1 - 0.5 10.0 12.9 0.089 12.4 4.0 2.5 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type Swi5 PF07061.11 KFQ97921.1 - 1.4 9.1 8.2 0.18 11.9 3.3 1.9 2 0 0 2 2 2 0 Swi5 zinc_ribbon_16 PF17034.5 KFQ97921.1 - 1.9 8.7 9.0 2.4 8.4 2.8 2.2 2 0 0 2 2 2 0 Zinc-ribbon like family SWIRM-assoc_2 PF16496.5 KFQ97922.1 - 2.2e-70 237.6 15.5 8e-36 123.8 0.1 3.1 3 0 0 3 3 3 3 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 KFQ97922.1 - 8.9e-33 112.5 0.1 1.7e-32 111.6 0.1 1.5 1 0 0 1 1 1 1 SWIRM domain Hormone_recep PF00104.30 KFQ97924.1 - 2.6e-42 144.7 0.1 4.9e-42 143.9 0.1 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFQ97924.1 - 1.8e-30 105.2 17.9 3.1e-30 104.4 17.9 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF1394 PF07159.12 KFQ97950.1 - 2.5e-139 463.7 0.8 2.8e-139 463.5 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) Ribosomal_S7e PF01251.18 KFQ97951.1 - 2.3e-79 265.5 5.0 2.5e-79 265.3 5.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DEAD PF00270.29 KFQ97952.1 - 4.9e-78 260.9 0.0 7.7e-78 260.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFQ97952.1 - 1.4e-27 96.2 0.1 5.5e-27 94.3 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SPRY PF00622.28 KFQ97952.1 - 1.5e-23 83.2 0.9 2.6e-23 82.4 0.2 1.8 2 0 0 2 2 2 1 SPRY domain CMS1 PF14617.6 KFQ97952.1 - 0.003 16.9 0.1 0.013 14.8 0.0 1.9 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 KFQ97952.1 - 0.0097 15.9 0.0 0.32 11.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Nbas_N PF15492.6 KFQ97953.1 - 3.4e-174 577.8 0.2 5.6e-174 577.1 0.2 1.4 1 0 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal ANAPC4_WD40 PF12894.7 KFQ97953.1 - 0.022 15.1 0.0 5.7 7.3 0.0 3.4 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain GP67 PF17634.2 KFQ97953.1 - 0.22 12.0 3.0 0.53 10.7 3.0 1.6 1 0 0 1 1 1 0 Gene product 67 LRAT PF04970.13 KFQ97954.1 - 9.2e-10 38.9 0.1 9.5e-05 22.7 0.0 2.5 1 1 1 2 2 2 2 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 KFQ97954.1 - 0.0036 17.3 0.0 0.013 15.5 0.0 1.9 1 1 0 1 1 1 1 NlpC/P60 family Keratin PF02422.16 KFQ97968.1 - 1.5e-34 117.5 19.2 1.7e-34 117.4 19.2 1.0 1 0 0 1 1 1 1 Keratin DnaJ PF00226.31 KFQ97975.1 - 3.4e-14 52.7 0.0 3.5e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 DnaJ domain DUF1387 PF07139.11 KFQ97976.1 - 4.8e-127 424.0 9.5 5.5e-127 423.8 9.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1387) T3SchapCesA PF11439.8 KFQ97976.1 - 0.042 14.0 0.7 6.1 7.0 0.0 2.7 2 0 0 2 2 2 0 Type III secretion system filament chaperone CesA IRK_N PF08466.10 KFQ97976.1 - 0.12 12.6 0.9 0.28 11.4 0.4 1.9 2 0 0 2 2 2 0 Inward rectifier potassium channel N-terminal DUF2368 PF10166.9 KFQ97976.1 - 1.4 8.5 4.5 2.3 7.8 4.5 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) MCRS_N PF13325.6 KFQ97977.1 - 8.7e-68 228.3 1.3 1e-67 228.0 1.3 1.0 1 0 0 1 1 1 1 N-terminal region of micro-spherule protein Myb_DNA-binding PF00249.31 KFQ97977.1 - 0.0019 18.3 0.1 3.6 7.9 0.0 3.2 4 0 0 4 4 4 2 Myb-like DNA-binding domain LRR19-TM PF15176.6 KFQ97978.1 - 0.0054 16.7 0.6 0.0058 16.6 0.6 1.1 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain Integrin_alpha PF00357.20 KFQ97978.1 - 0.0056 16.6 1.7 0.0089 15.9 1.7 1.4 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region LYRIC PF15686.5 KFQ97978.1 - 0.013 15.1 1.0 0.013 15.0 1.0 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family DUF4381 PF14316.6 KFQ97978.1 - 0.016 15.5 2.2 0.016 15.5 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) COX6C PF02937.15 KFQ97978.1 - 0.069 13.3 0.5 0.087 13.0 0.5 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc DUF3328 PF11807.8 KFQ97978.1 - 0.074 12.8 0.2 0.079 12.7 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) LapA_dom PF06305.11 KFQ97978.1 - 0.11 12.4 1.5 0.12 12.2 1.5 1.1 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain SurA_N_2 PF13623.6 KFQ97978.1 - 0.11 12.3 0.1 0.14 12.0 0.1 1.1 1 0 0 1 1 1 0 SurA N-terminal domain DUF2207 PF09972.9 KFQ97978.1 - 0.16 10.7 1.2 0.16 10.7 1.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Protocadherin PF08374.11 KFQ97978.1 - 0.22 11.5 0.0 0.24 11.3 0.0 1.0 1 0 0 1 1 1 0 Protocadherin DUF4131 PF13567.6 KFQ97978.1 - 0.26 10.9 2.5 0.26 10.9 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Ras PF00071.22 KFQ97985.1 - 2.9e-25 88.8 0.2 3.2e-25 88.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ97985.1 - 4.1e-11 43.1 0.0 4.9e-11 42.9 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ97985.1 - 0.00035 20.1 0.1 0.00041 19.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family ParE_toxin PF05016.15 KFQ97985.1 - 0.079 13.6 0.0 0.1 13.2 0.0 1.2 1 0 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE Oest_recep PF02159.15 KFQ97994.1 - 3.5e-67 225.2 8.5 3.5e-67 225.2 8.5 1.9 2 0 0 2 2 2 1 Oestrogen receptor Hormone_recep PF00104.30 KFQ97994.1 - 6.4e-34 117.3 3.6 1.1e-33 116.6 3.6 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFQ97994.1 - 1.5e-31 108.7 13.9 2.6e-31 107.9 13.9 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) ESR1_C PF12743.7 KFQ97994.1 - 5.8e-20 70.8 3.1 5.8e-20 70.8 3.1 2.2 2 0 0 2 2 2 1 Oestrogen-type nuclear receptor final C-terminal Thyroglob_assoc PF16597.5 KFQ97994.1 - 0.011 16.1 0.1 0.022 15.0 0.1 1.5 1 0 0 1 1 1 0 Thyroglobulin_1 repeat associated disordered domain HAP1_N PF04849.13 KFQ97995.1 - 0.00012 21.4 14.9 0.00012 21.4 14.9 5.8 1 1 3 5 5 5 1 HAP1 N-terminal conserved region Filament PF00038.21 KFQ97995.1 - 0.0026 17.4 8.7 0.0026 17.4 8.7 6.7 1 1 2 5 5 5 3 Intermediate filament protein Lipocalin_2 PF08212.12 KFQ97995.1 - 2.8 7.8 5.8 0.66 9.9 1.0 2.3 2 1 0 2 2 2 0 Lipocalin-like domain DUF3800 PF12686.7 KFQ97995.1 - 6.4 7.4 9.4 3.3e+03 -1.3 9.1 3.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) DUF89 PF01937.19 KFQ97996.1 - 1.3e-124 415.7 0.7 1.5e-124 415.5 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 KRBA1 PF15287.6 KFQ97996.1 - 0.038 13.7 0.1 0.077 12.7 0.1 1.4 1 0 0 1 1 1 0 KRBA1 family repeat DUF155 PF02582.14 KFQ97997.1 - 1.5e-47 162.0 2.4 2.2e-47 161.4 2.4 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 BTB PF00651.31 KFQ97998.1 - 4.3e-19 68.8 0.2 9e-19 67.8 0.2 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 KFQ97998.1 - 3.2e-14 52.5 30.2 0.00023 21.5 1.5 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ97998.1 - 2.6e-12 46.6 19.9 0.00013 22.3 2.9 5.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ97998.1 - 3.2e-09 36.8 27.2 0.012 16.4 1.3 5.1 5 0 0 5 5 4 3 C2H2-type zinc finger zf-met PF12874.7 KFQ97998.1 - 1.1e-08 35.1 21.9 0.16 12.4 1.5 4.8 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFQ97998.1 - 5.8e-07 29.6 16.6 0.014 15.7 0.1 4.7 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 KFQ97998.1 - 9.1e-05 23.1 8.5 0.25 12.0 0.0 3.9 2 1 2 4 4 4 2 Zinc finger C2H2-type, 3 repeats zf-C2HE PF16278.5 KFQ97998.1 - 0.032 14.7 15.8 6.2 7.3 0.1 4.5 3 1 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 KFQ97998.1 - 0.037 14.0 30.5 0.74 9.9 0.5 4.8 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFQ97998.1 - 0.098 12.6 19.0 0.36 10.8 0.4 4.3 4 0 0 4 4 4 0 zinc-finger of a C2HC-type FYVE PF01363.21 KFQ97998.1 - 0.18 12.0 16.5 5.9 7.1 0.0 3.9 3 1 0 3 3 3 0 FYVE zinc finger zf-C2H2_2 PF12756.7 KFQ97998.1 - 0.25 11.7 17.5 4.1 7.8 0.3 3.5 2 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-AN1 PF01428.16 KFQ97998.1 - 1.3 9.3 21.7 0.31 11.2 2.7 4.7 4 1 0 4 4 4 0 AN1-like Zinc finger Zn-ribbon_8 PF09723.10 KFQ97998.1 - 1.4 9.1 16.2 5 7.3 0.1 4.4 4 0 0 4 4 4 0 Zinc ribbon domain zf-CCHC_2 PF13696.6 KFQ97998.1 - 3.6 7.5 15.9 10 6.0 2.2 3.7 3 0 0 3 3 3 0 Zinc knuckle zf_UBZ PF18439.1 KFQ97998.1 - 5.3 6.7 12.4 24 4.6 0.4 4.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger DUF447 PF04289.12 KFQ98000.1 - 0.069 12.9 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF447) WSK PF03832.13 KFQ98001.1 - 1e-12 47.5 9.5 1.1e-11 44.2 2.6 3.9 4 0 0 4 4 4 2 WSK motif MgpC PF05220.12 KFQ98001.1 - 0.017 14.5 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 MgpC protein precursor PCB_OB PF17092.5 KFQ98001.1 - 2.5 8.9 7.2 2.5 8.9 4.4 2.5 1 1 1 2 2 2 0 Penicillin-binding protein OB-like domain RhoGEF PF00621.20 KFQ98002.1 - 1.1e-44 152.8 1.6 1.1e-44 152.8 1.6 2.1 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 KFQ98002.1 - 0.00017 22.1 0.2 0.00059 20.3 0.1 2.0 1 1 0 1 1 1 1 PH domain PH_10 PF15411.6 KFQ98002.1 - 0.017 15.4 0.1 0.017 15.4 0.1 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain NOG1_N PF17835.1 KFQ98002.1 - 0.022 14.7 0.3 2.5 8.1 0.1 2.8 2 0 0 2 2 2 0 NOG1 N-terminal helical domain IQ_SEC7_PH PF16453.5 KFQ98002.1 - 0.073 13.0 0.2 0.27 11.2 0.2 2.0 1 0 0 1 1 1 0 PH domain SICA_alpha PF12887.7 KFQ98002.1 - 0.085 12.7 0.1 0.25 11.2 0.1 1.8 1 0 0 1 1 1 0 SICA extracellular alpha domain PH_16 PF17838.1 KFQ98002.1 - 0.11 12.3 1.1 0.58 10.0 0.6 2.4 2 1 0 2 2 2 0 PH domain Syntaxin_2 PF14523.6 KFQ98002.1 - 0.37 11.2 4.5 0.61 10.5 0.1 2.8 2 0 0 2 2 2 0 Syntaxin-like protein Nitroreductase PF00881.24 KFQ98004.1 - 1.3e-19 70.9 0.0 1.9e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KFQ98004.1 - 0.0012 18.5 0.0 7 6.1 0.0 3.1 2 1 1 3 3 3 3 Putative TM nitroreductase Ldl_recept_a PF00057.18 KFQ98007.1 - 8.6e-08 32.3 11.9 1.6e-07 31.4 11.9 1.5 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A PKD PF00801.20 KFQ98007.1 - 0.12 12.2 0.1 0.54 10.1 0.0 2.1 2 0 0 2 2 2 0 PKD domain PCMT PF01135.19 KFQ98008.1 - 1.8e-81 272.9 0.0 2e-81 272.7 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KFQ98008.1 - 4.4e-07 30.5 0.0 7.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFQ98008.1 - 1.6e-06 28.0 0.0 3.4e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFQ98008.1 - 6.4e-05 23.5 0.1 0.00018 22.1 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFQ98008.1 - 8e-05 22.1 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GCD14 PF08704.10 KFQ98008.1 - 0.00011 22.0 0.0 0.00013 21.7 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PrmA PF06325.13 KFQ98008.1 - 0.00014 21.4 0.0 0.00016 21.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KFQ98008.1 - 0.0018 18.2 0.0 0.0055 16.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFQ98008.1 - 0.026 14.1 0.1 0.037 13.6 0.1 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 KFQ98008.1 - 0.073 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Fibrillarin PF01269.17 KFQ98008.1 - 0.092 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin FtsJ PF01728.19 KFQ98008.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 KFQ98008.1 - 0.18 11.5 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase WD40 PF00400.32 KFQ98009.1 - 1.1e-06 29.2 5.9 0.0031 18.3 0.1 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat GHD PF17834.1 KFQ98009.1 - 0.028 14.5 0.0 10 6.3 0.0 2.7 2 0 0 2 2 2 0 Beta-sandwich domain in beta galactosidase Hira PF07569.11 KFQ98009.1 - 0.065 12.9 0.1 26 4.5 0.0 3.1 1 1 2 3 3 3 0 TUP1-like enhancer of split PHTB1_N PF14727.6 KFQ98009.1 - 0.11 11.9 0.0 2.5 7.3 0.0 2.4 2 1 0 2 2 2 0 PTHB1 N-terminus BBS2_Mid PF14783.6 KFQ98009.1 - 0.14 12.2 0.1 5.7 7.0 0.0 2.6 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Pkinase PF00069.25 KFQ98010.1 - 2e-61 207.7 0.6 1.5e-39 135.9 0.0 3.1 4 0 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ98010.1 - 2.6e-28 99.0 0.0 5.5e-20 71.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase UBA PF00627.31 KFQ98010.1 - 2.1e-10 40.3 0.8 2.1e-10 40.3 0.8 2.2 2 0 0 2 2 2 1 UBA/TS-N domain Haspin_kinase PF12330.8 KFQ98010.1 - 0.0007 18.6 0.1 0.0013 17.8 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFQ98010.1 - 0.0035 17.3 0.4 0.023 14.6 0.3 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFQ98010.1 - 0.0036 16.7 0.1 0.024 13.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like UBA_3 PF09288.10 KFQ98010.1 - 0.05 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Pkinase_C PF00433.24 KFQ98010.1 - 0.061 14.0 0.9 0.32 11.7 0.9 2.3 1 0 0 1 1 1 0 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.11 KFQ98010.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Cas_Cas6 PF01881.16 KFQ98010.1 - 0.14 12.7 1.5 0.27 11.8 1.5 1.4 1 0 0 1 1 1 0 CRISPR associated protein Cas6 HOIP-UBA PF16678.5 KFQ98010.1 - 0.16 12.0 0.8 0.78 9.7 0.0 2.1 2 0 0 2 2 2 0 HOIP UBA domain pair AAA PF00004.29 KFQ98011.1 - 1.1e-39 135.9 0.0 2.1e-39 134.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFQ98011.1 - 9.8e-17 60.5 1.2 9.7e-16 57.3 1.2 2.7 1 1 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 KFQ98011.1 - 5.6e-09 35.9 0.2 2.3e-08 33.9 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 KFQ98011.1 - 6.1e-06 26.5 0.1 1.7e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KFQ98011.1 - 1.3e-05 25.0 0.0 5.5e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KFQ98011.1 - 4.8e-05 23.5 0.0 0.00015 21.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 KFQ98011.1 - 0.00053 20.0 0.3 0.0039 17.2 0.3 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KFQ98011.1 - 0.0011 18.3 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KFQ98011.1 - 0.0015 18.3 0.0 0.0081 15.9 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 KFQ98011.1 - 0.0018 18.3 0.1 0.0055 16.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 KFQ98011.1 - 0.0033 16.8 0.0 0.0074 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KFQ98011.1 - 0.0043 17.4 0.1 0.011 16.1 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KFQ98011.1 - 0.0045 16.5 0.2 0.012 15.2 0.2 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KFQ98011.1 - 0.005 17.1 1.5 0.079 13.2 0.4 3.1 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 KFQ98011.1 - 0.0062 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 KFQ98011.1 - 0.0076 15.6 0.5 1.1 8.5 0.1 2.6 2 1 1 3 3 2 1 KaiC PhoH PF02562.16 KFQ98011.1 - 0.023 14.1 0.1 0.054 13.0 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 KFQ98011.1 - 0.024 15.2 0.8 0.16 12.5 0.8 2.4 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KFQ98011.1 - 0.031 14.1 0.6 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFQ98011.1 - 0.062 13.7 0.4 0.22 11.9 0.0 2.1 2 1 0 2 2 1 0 RNA helicase ABC_tran PF00005.27 KFQ98011.1 - 0.062 13.8 0.0 0.39 11.2 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 KFQ98011.1 - 0.16 11.7 0.0 0.51 10.0 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 KFQ98011.1 - 0.16 11.7 1.6 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain TPR_1 PF00515.28 KFQ98011.1 - 0.17 11.8 0.2 0.57 10.1 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat NACHT PF05729.12 KFQ98011.1 - 0.17 11.8 0.1 0.49 10.3 0.1 1.8 1 1 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 KFQ98011.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TPR_8 PF13181.6 KFQ98011.1 - 0.19 12.0 0.8 0.51 10.7 0.1 2.2 2 0 0 2 2 1 0 Tetratricopeptide repeat Guanylate_kin PF00625.21 KFQ98011.1 - 0.24 11.0 1.8 1 9.0 0.0 2.7 3 0 0 3 3 3 0 Guanylate kinase TPR_2 PF07719.17 KFQ98011.1 - 0.33 11.2 1.7 1.2 9.4 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Pro_isomerase PF00160.21 KFQ98012.1 - 9e-31 107.3 0.3 2.3e-30 106.0 0.3 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KFQ98012.1 - 5.6e-18 64.5 0.0 1.1e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_Zc3h12a PF11977.8 KFQ98013.1 - 1.5e-64 216.5 0.0 2.1e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain UBA_6 PF18039.1 KFQ98013.1 - 3e-21 75.1 0.2 5.4e-21 74.2 0.2 1.5 1 0 0 1 1 1 1 UBA-like domain zf-CCCH_4 PF18044.1 KFQ98013.1 - 2.7e-05 23.9 5.5 2.7e-05 23.9 5.5 1.9 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 KFQ98013.1 - 0.02 14.8 5.6 0.038 13.9 3.7 2.3 1 1 1 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PRORP PF16953.5 KFQ98013.1 - 0.082 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein-only RNase P zf-CCCH_2 PF14608.6 KFQ98013.1 - 0.22 12.1 8.7 0.45 11.1 8.7 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Omega-toxin PF06357.11 KFQ98013.1 - 1.2 9.0 5.8 2.9 7.8 5.8 1.6 1 0 0 1 1 1 0 Omega-atracotoxin zf_CCCH_4 PF18345.1 KFQ98013.1 - 6.1 7.1 8.6 1.9 8.6 4.5 2.3 2 1 1 3 3 3 0 Zinc finger domain Sulfotransfer_2 PF03567.14 KFQ98014.1 - 3.3e-33 115.6 1.2 4.3e-33 115.3 1.2 1.1 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 KFQ98014.1 - 4.7e-08 32.3 0.3 6.5e-08 31.9 0.3 1.2 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase LLGL PF08366.13 KFQ98017.1 - 5.9e-34 116.5 0.0 1.6e-33 115.2 0.0 1.8 1 0 0 1 1 1 1 LLGL2 ANAPC4_WD40 PF12894.7 KFQ98017.1 - 2.3e-11 43.9 1.1 0.029 14.7 0.1 6.2 4 1 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFQ98017.1 - 2.2e-09 37.8 9.1 0.0035 18.2 0.7 6.6 6 1 0 6 6 6 2 WD domain, G-beta repeat Lgl_C PF08596.10 KFQ98017.1 - 2.9e-07 29.6 0.1 9.6e-06 24.5 0.0 3.1 3 1 0 3 3 3 1 Lethal giant larvae(Lgl) like, C-terminal WD40_like PF17005.5 KFQ98017.1 - 0.0024 17.2 0.0 0.021 14.2 0.0 2.3 1 1 0 1 1 1 1 WD40-like domain Synaptobrevin PF00957.21 KFQ98017.1 - 0.0026 17.5 0.0 0.0074 16.1 0.0 1.8 1 0 0 1 1 1 1 Synaptobrevin RAB3GAP2_N PF14655.6 KFQ98017.1 - 0.0044 16.3 0.0 2.8 7.1 0.0 3.3 3 0 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus ELYS-bb PF16687.5 KFQ98017.1 - 0.0058 15.3 0.0 9.9 4.6 0.0 3.3 2 1 1 3 3 3 1 beta-propeller of ELYS nucleoporin Frtz PF11768.8 KFQ98017.1 - 0.0063 14.9 0.1 0.017 13.4 0.0 1.7 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Hira PF07569.11 KFQ98017.1 - 0.082 12.6 0.0 3.6 7.3 0.0 3.2 2 1 2 4 4 4 0 TUP1-like enhancer of split Globin PF00042.22 KFQ98018.1 - 1.1e-07 32.4 0.1 0.00012 22.6 0.0 2.3 2 0 0 2 2 2 2 Globin IQ PF00612.27 KFQ98018.1 - 0.033 14.0 0.1 0.073 12.9 0.1 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif NUMOD1 PF07453.13 KFQ98018.1 - 0.064 13.5 0.1 0.28 11.5 0.1 2.1 1 0 0 1 1 1 0 NUMOD1 domain Ras PF00071.22 KFQ98021.1 - 2.1e-38 131.5 0.0 2.4e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ98021.1 - 3.8e-28 98.1 0.0 4.7e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ98021.1 - 1.8e-09 37.3 0.0 2.1e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFQ98021.1 - 2.4e-06 27.1 0.0 2.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFQ98021.1 - 0.0002 21.4 0.0 0.00024 21.1 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 KFQ98021.1 - 0.0019 17.8 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KFQ98021.1 - 0.0022 18.3 0.0 0.0029 17.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 KFQ98021.1 - 0.0032 17.0 0.0 0.11 12.0 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KFQ98021.1 - 0.0051 16.6 0.0 1.7 8.3 0.0 2.0 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KFQ98021.1 - 0.043 14.2 0.1 0.067 13.6 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 KFQ98021.1 - 0.047 13.1 0.0 0.27 10.6 0.0 1.9 1 1 1 2 2 2 0 Bacterial TniB protein PduV-EutP PF10662.9 KFQ98021.1 - 0.048 13.4 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 KFQ98021.1 - 0.068 12.3 0.0 0.095 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 KFQ98021.1 - 0.079 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KFQ98021.1 - 0.098 12.4 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KFQ98021.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 KFQ98021.1 - 0.12 12.8 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFQ98021.1 - 0.17 11.9 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRPRB PF09439.10 KFQ98021.1 - 0.17 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ANF_receptor PF01094.28 KFQ98022.1 - 5.2e-95 318.5 0.0 7.7e-95 318.0 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 KFQ98022.1 - 1.1e-56 192.2 27.5 1.6e-56 191.7 27.5 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR GluR_Homer-bdg PF10606.9 KFQ98022.1 - 5.4e-25 87.3 9.6 1.5e-24 85.9 9.6 1.8 1 0 0 1 1 1 1 Homer-binding domain of metabotropic glutamate receptor NCD3G PF07562.14 KFQ98022.1 - 2.3e-15 56.3 10.4 4.8e-15 55.3 10.4 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR DUF5438 PF17506.2 KFQ98022.1 - 0.059 13.7 0.4 0.21 11.9 0.4 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5438) SNF2_N PF00176.23 KFQ98023.1 - 8.3e-132 439.1 2.8 8.3e-132 439.1 2.8 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Linker_histone PF00538.19 KFQ98023.1 - 2.4e-20 72.7 0.6 2.5e-19 69.4 0.2 2.8 2 0 0 2 2 2 1 linker histone H1 and H5 family Helicase_C PF00271.31 KFQ98023.1 - 6e-08 33.0 0.0 2.2e-07 31.2 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD PF00628.29 KFQ98023.1 - 7.4e-06 25.8 6.9 7.4e-06 25.8 6.9 3.8 3 1 0 3 3 2 1 PHD-finger zf-RING_UBOX PF13445.6 KFQ98023.1 - 1.2e-05 25.3 5.9 1.2e-05 25.3 5.9 2.3 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFQ98023.1 - 0.0001 22.1 9.8 0.0001 22.1 9.8 3.0 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ98023.1 - 0.00022 21.5 9.9 0.00022 21.5 9.9 3.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KFQ98023.1 - 0.00024 20.9 9.7 0.00024 20.9 9.7 2.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFQ98023.1 - 0.0016 18.3 4.9 0.0016 18.3 4.9 3.0 4 0 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFQ98023.1 - 0.0018 18.2 9.5 0.0018 18.2 9.5 3.0 2 1 1 3 3 3 1 zinc-RING finger domain PEP-utilisers_N PF05524.13 KFQ98023.1 - 0.065 13.4 2.3 0.11 12.6 0.6 2.3 2 0 0 2 2 1 0 PEP-utilising enzyme, N-terminal TPR_7 PF13176.6 KFQ98023.1 - 0.11 12.5 0.1 0.33 11.1 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Aminotran_3 PF00202.21 KFQ98023.1 - 0.72 8.4 3.3 2.1 6.9 0.2 2.8 3 0 0 3 3 3 0 Aminotransferase class-III Prok-RING_4 PF14447.6 KFQ98023.1 - 0.72 9.8 13.5 0.074 12.9 7.9 2.4 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 F-box_4 PF15966.5 KFQ98024.1 - 2.6e-50 169.1 0.9 2.6e-50 169.1 0.9 2.2 2 0 0 2 2 2 1 F-box zf-TRAF_2 PF15965.5 KFQ98024.1 - 2.1e-38 130.7 15.0 2.1e-38 130.7 15.0 2.9 3 1 0 3 3 3 1 TRAF-like zinc-finger F-box PF00646.33 KFQ98024.1 - 2.1e-07 30.6 0.8 5.9e-07 29.2 0.8 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFQ98024.1 - 2e-06 27.6 0.2 6.2e-06 26.0 0.2 1.8 1 0 0 1 1 1 1 F-box-like zf-TRAF PF02176.18 KFQ98024.1 - 0.0043 17.7 1.9 0.0043 17.7 1.9 4.3 6 0 0 6 6 6 1 TRAF-type zinc finger DUF4644 PF15486.6 KFQ98024.1 - 0.034 13.9 0.6 5 6.9 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4644) DSPc PF00782.20 KFQ98025.1 - 1e-13 51.3 0.0 2e-13 50.3 0.0 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain AAA_25 PF13481.6 KFQ98025.1 - 0.013 15.1 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Y_phosphatase2 PF03162.13 KFQ98025.1 - 0.019 14.6 0.0 0.049 13.2 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family CDKN3 PF05706.12 KFQ98025.1 - 0.051 13.3 0.0 0.079 12.6 0.0 1.4 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) AlaDh_PNT_N PF05222.15 KFQ98025.1 - 0.17 12.2 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain Spectrin PF00435.21 KFQ98026.1 - 6.2e-17 62.0 18.6 8.1e-11 42.3 5.8 2.9 2 1 1 3 3 3 2 Spectrin repeat EFhand_Ca_insen PF08726.10 KFQ98026.1 - 0.034 14.2 0.1 0.14 12.3 0.1 2.0 1 0 0 1 1 1 0 Ca2+ insensitive EF hand NPV_P10 PF05531.12 KFQ98026.1 - 0.075 13.5 13.7 0.32 11.5 0.5 4.3 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein MnmE_helical PF12631.7 KFQ98026.1 - 0.098 12.8 4.6 0.13 12.4 4.6 1.1 1 0 0 1 1 1 0 MnmE helical domain DUF948 PF06103.11 KFQ98026.1 - 0.27 11.5 8.3 36 4.7 0.0 4.1 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Uteroglobin PF01099.17 KFQ98026.1 - 0.29 11.5 3.8 1.5 9.2 1.9 2.5 2 0 0 2 2 2 0 Uteroglobin family DASH_Dam1 PF08653.10 KFQ98026.1 - 0.89 9.4 4.7 9.3 6.1 0.1 4.0 5 0 0 5 5 5 0 DASH complex subunit Dam1 Rab5-bind PF09311.11 KFQ98026.1 - 1.4 8.3 19.5 1.5 8.2 5.3 2.8 2 1 1 3 3 3 0 Rabaptin-like protein FAD_SOX PF18371.1 KFQ98026.1 - 1.7 9.0 5.3 28 5.1 0.0 3.3 2 2 1 4 4 4 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase HetR_C PF18460.1 KFQ98026.1 - 3 7.8 7.8 0.62 10.0 0.1 3.4 2 1 1 4 4 4 0 Heterocyst differentiation regulator C-terminal Hood domain CorA PF01544.18 KFQ98026.1 - 8.2 5.6 13.3 1.6 7.9 6.2 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein CH PF00307.31 KFQ98027.1 - 1.1e-42 144.7 9.2 9e-22 77.3 0.1 4.1 5 1 0 5 5 5 2 Calponin homology (CH) domain Spectrin PF00435.21 KFQ98027.1 - 2e-42 143.9 86.5 1.2e-14 54.7 4.1 7.8 8 0 0 8 8 8 7 Spectrin repeat CAMSAP_CH PF11971.8 KFQ98027.1 - 2.6e-05 24.0 0.0 0.028 14.3 0.0 3.2 2 0 0 2 2 2 2 CAMSAP CH domain Mating_N PF12731.7 KFQ98027.1 - 0.007 16.4 1.1 0.056 13.5 0.4 3.1 2 0 0 2 2 2 1 Mating-type protein beta 1 Pfg27 PF09216.10 KFQ98027.1 - 0.035 14.0 1.7 0.078 12.8 0.3 2.3 2 0 0 2 2 2 0 Pfg27 DUF3288 PF11691.8 KFQ98027.1 - 0.14 12.2 10.5 3.2 7.9 0.1 5.4 5 0 0 5 5 5 0 Protein of unknown function (DUF3288) DUF5304 PF17230.2 KFQ98027.1 - 0.71 10.1 5.3 1.1 9.5 0.9 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5304) AbiEi_1 PF09407.10 KFQ98027.1 - 9.6 6.5 7.8 6.9 7.0 0.0 3.8 5 0 0 5 5 5 0 AbiEi antitoxin C-terminal domain Syntaxin PF00804.25 KFQ98028.1 - 6.9e-64 215.2 14.5 6.9e-64 215.2 14.5 1.4 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 KFQ98028.1 - 2.2e-05 24.4 1.7 5.2e-05 23.1 0.0 2.4 3 0 0 3 3 3 1 SNARE domain Herpes_BLRF2 PF05812.12 KFQ98028.1 - 0.0026 17.9 2.6 0.017 15.3 0.7 2.3 1 1 1 2 2 2 1 Herpesvirus BLRF2 protein DUF1217 PF06748.12 KFQ98028.1 - 0.022 14.8 0.3 0.053 13.6 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1217) FUSC PF04632.12 KFQ98028.1 - 0.047 12.2 0.4 0.068 11.7 0.3 1.2 1 1 0 1 1 1 0 Fusaric acid resistance protein family MbeD_MobD PF04899.12 KFQ98028.1 - 0.1 12.7 0.8 1.5 9.0 0.1 2.6 2 0 0 2 2 2 0 MbeD/MobD like HMMR_C PF15908.5 KFQ98028.1 - 0.13 12.5 3.8 4 7.7 0.4 2.6 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Toprim_Crpt PF13342.6 KFQ98028.1 - 0.16 12.0 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase AbbA_antirepres PF14156.6 KFQ98028.1 - 0.21 11.5 3.0 0.26 11.2 0.6 2.2 2 1 0 2 2 2 0 Antirepressor AbbA HisKA_3 PF07730.13 KFQ98028.1 - 0.24 12.0 3.8 1.9 9.1 0.5 3.5 2 2 2 4 4 4 0 Histidine kinase DivIC PF04977.15 KFQ98028.1 - 0.5 10.2 4.9 0.29 10.9 0.3 2.8 3 0 0 3 3 3 0 Septum formation initiator FlaC_arch PF05377.11 KFQ98028.1 - 0.59 10.6 6.7 2.1 8.8 0.1 3.8 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) Spectrin PF00435.21 KFQ98028.1 - 0.65 10.5 9.8 0.36 11.3 2.6 2.7 2 2 0 2 2 2 0 Spectrin repeat TetR PF13972.6 KFQ98028.1 - 0.95 9.2 4.9 0.21 11.3 0.4 2.3 3 0 0 3 3 3 0 Bacterial transcriptional repressor CENP-H PF05837.12 KFQ98028.1 - 2.2 8.7 6.4 1.3 9.5 0.6 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) SF3b10 PF07189.11 KFQ98029.1 - 1.6e-40 137.1 0.0 1.8e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF2264 PF10022.9 KFQ98029.1 - 0.022 13.9 0.2 0.024 13.7 0.2 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) fn3 PF00041.21 KFQ98030.1 - 1.4e-30 105.4 13.1 3.1e-10 40.3 0.0 5.2 6 0 0 6 6 6 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFQ98030.1 - 1.9e-07 31.6 2.6 0.003 18.1 0.1 5.1 6 0 0 6 6 6 3 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFQ98030.1 - 2.9e-06 27.5 0.0 0.25 11.7 0.3 3.7 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 KFQ98030.1 - 0.0067 16.8 0.0 2.6 8.5 0.0 3.8 3 0 0 3 3 3 1 Uncharacterised conserved protein (DUF2369) Sod_Fe_C PF02777.18 KFQ98031.1 - 1.1e-38 131.5 0.0 1.9e-38 130.7 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KFQ98031.1 - 2.4e-34 117.6 2.5 3.7e-34 117.0 2.5 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Wtap PF17098.5 KFQ98032.1 - 1.4e-61 207.0 13.7 1.4e-61 207.0 13.7 2.4 2 1 0 2 2 2 1 WTAP/Mum2p family Atg14 PF10186.9 KFQ98032.1 - 0.014 14.5 20.0 0.083 12.0 5.2 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 KFQ98032.1 - 0.18 11.8 31.3 0.51 10.4 5.8 3.6 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding SPACA9 PF15120.6 KFQ98032.1 - 2.7 7.8 16.1 0.038 13.8 5.5 2.3 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 DUF2120 PF09893.9 KFQ98032.1 - 5.5 7.1 7.3 1.7 8.7 0.2 2.9 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) Spc7 PF08317.11 KFQ98032.1 - 5.8 5.7 31.7 11 4.8 13.7 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1515 PF07439.11 KFQ98032.1 - 7.8 6.6 6.9 1.6 8.8 1.1 2.6 2 2 2 4 4 4 0 Protein of unknown function (DUF1515) Tropomyosin_1 PF12718.7 KFQ98032.1 - 8.3 6.6 26.4 0.23 11.6 5.0 3.0 2 1 0 2 2 2 0 Tropomyosin like Thiolase_N PF00108.23 KFQ98033.1 - 1.9e-77 260.1 1.4 2.8e-77 259.6 1.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFQ98033.1 - 9.3e-51 170.6 0.8 1.8e-50 169.7 0.8 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFQ98033.1 - 0.00032 20.4 1.3 0.00032 20.4 1.3 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Dodecin PF07311.12 KFQ98033.1 - 0.0023 18.2 0.1 0.0055 16.9 0.1 1.6 1 0 0 1 1 1 1 Dodecin ACP_syn_III_C PF08541.10 KFQ98033.1 - 0.0042 17.2 0.1 0.013 15.7 0.1 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal P33MONOX PF15302.6 KFQ98033.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 P33 mono-oxygenase Cpn60_TCP1 PF00118.24 KFQ98034.1 - 3.4e-153 510.8 14.7 3.9e-153 510.6 14.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_L18p PF00861.22 KFQ98035.1 - 3.2e-05 24.3 0.0 5.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast DMA PF03474.14 KFQ98035.1 - 0.023 14.3 0.3 0.056 13.0 0.0 1.7 2 0 0 2 2 2 0 DMRTA motif CAF1 PF04857.20 KFQ98036.1 - 1.1e-72 244.9 0.1 1.5e-72 244.5 0.1 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease RNA_bind PF08675.11 KFQ98036.1 - 0.11 12.6 0.1 0.3 11.1 0.1 1.8 1 0 0 1 1 1 0 RNA binding domain 7tm_1 PF00001.21 KFQ98037.1 - 8e-18 64.7 27.6 8e-18 64.7 27.6 1.6 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFQ98037.1 - 3.7e-09 36.6 21.6 3.7e-09 36.6 21.6 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.15 KFQ98037.1 - 0.0084 16.1 14.1 0.0084 16.1 14.1 2.9 1 1 2 3 3 3 1 Caenorhabditis serpentine receptor-like protein, class xa ISK_Channel PF02060.15 KFQ98037.1 - 0.18 11.5 2.2 0.86 9.3 0.0 2.6 2 1 0 2 2 2 0 Slow voltage-gated potassium channel CIMR PF00878.18 KFQ98038.1 - 0 1224.4 95.5 1.9e-52 177.2 2.9 16.5 16 1 0 16 16 16 15 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 KFQ98038.1 - 2.7e-62 211.0 95.8 9.4e-09 35.5 0.5 16.0 3 2 12 15 15 15 13 Autophagy-related protein 27 Man-6-P_recep PF02157.15 KFQ98038.1 - 8.9e-46 156.0 45.1 3.3e-10 39.5 0.9 13.6 6 3 8 15 15 15 11 Mannose-6-phosphate receptor fn2 PF00040.19 KFQ98038.1 - 1.4e-18 66.9 7.8 5.5e-18 65.0 7.8 2.2 1 0 0 1 1 1 1 Fibronectin type II domain PRKCSH_1 PF13015.6 KFQ98038.1 - 3.5e-07 30.0 45.6 0.02 14.6 0.2 10.3 11 1 0 12 12 12 5 Glucosidase II beta subunit-like protein DUF4448 PF14610.6 KFQ98038.1 - 0.00029 20.7 0.4 9 6.0 0.0 3.9 3 0 0 3 3 3 2 Protein of unknown function (DUF4448) Sugar_tr PF00083.24 KFQ98039.1 - 1.5e-35 123.0 8.6 1.5e-35 123.0 8.6 1.4 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KFQ98039.1 - 8e-28 97.4 23.4 5.6e-26 91.3 10.9 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_4 PF06779.14 KFQ98039.1 - 0.0054 16.1 0.5 0.0054 16.1 0.5 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB RVT_1 PF00078.27 KFQ98082.1 - 0.0088 15.6 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AdenylateSensor PF16579.5 KFQ98083.1 - 5.6e-13 49.4 0.1 1.4e-12 48.1 0.1 1.6 1 1 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase TMEM174 PF15029.6 KFQ98085.1 - 8.3e-119 395.5 0.1 9.4e-119 395.3 0.1 1.0 1 0 0 1 1 1 1 Transmembrane protein 174 TMEM171 PF15471.6 KFQ98086.1 - 2.4e-155 516.4 2.4 2.6e-155 516.2 2.4 1.0 1 0 0 1 1 1 1 Transmembrane protein family 171 DUF2371 PF10177.9 KFQ98086.1 - 0.16 12.1 0.3 1.8 8.7 0.3 2.3 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) SdpI PF13630.6 KFQ98086.1 - 0.87 9.8 5.1 12 6.1 0.4 3.4 3 1 0 3 3 3 0 SdpI/YhfL protein family Tetraspanin PF00335.20 KFQ98086.1 - 2.5 7.7 11.0 1.1 9.0 1.7 2.2 2 0 0 2 2 2 0 Tetraspanin family Phage_holin_3_6 PF07332.11 KFQ98086.1 - 2.5 8.2 9.6 6.4 6.9 4.2 2.4 1 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III muHD PF10291.9 KFQ98087.1 - 1.3e-63 214.9 0.3 2e-63 214.3 0.3 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Keratin PF02422.16 KFQ98090.1 - 3.9e-22 77.8 10.0 4.1e-22 77.7 10.0 1.0 1 0 0 1 1 1 1 Keratin DnaJ PF00226.31 KFQ98092.1 - 3.4e-29 100.8 5.7 5.4e-29 100.1 5.7 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 KFQ98092.1 - 2.6e-24 86.0 0.3 3.6e-24 85.5 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain RPT PF13446.6 KFQ98092.1 - 0.15 12.0 0.2 0.33 10.9 0.2 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein fn3 PF00041.21 KFQ98101.1 - 9.4e-90 295.1 12.4 7.6e-19 67.8 0.1 6.4 6 0 0 6 6 6 5 Fibronectin type III domain I-set PF07679.16 KFQ98101.1 - 6.1e-67 221.7 9.9 4.2e-20 71.6 0.0 8.3 9 0 0 9 9 8 7 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ98101.1 - 1.2e-49 166.8 1.3 1.7e-12 47.8 0.0 8.1 8 0 0 8 8 7 6 Immunoglobulin domain Ig_2 PF13895.6 KFQ98101.1 - 1.9e-32 111.5 0.4 1.1e-07 32.1 0.0 7.3 7 0 0 7 7 7 4 Immunoglobulin domain ig PF00047.25 KFQ98101.1 - 1.7e-25 89.0 9.9 5.8e-09 36.0 0.0 8.0 8 0 0 8 8 8 5 Immunoglobulin domain V-set PF07686.17 KFQ98101.1 - 5.9e-17 61.8 16.8 0.03 14.5 0.1 10.9 8 4 1 9 9 8 4 Immunoglobulin V-set domain Tissue_fac PF01108.17 KFQ98101.1 - 2.3e-12 46.7 0.6 0.012 15.4 0.0 5.6 6 0 0 6 6 6 4 Tissue factor Pur_ac_phosph_N PF16656.5 KFQ98101.1 - 1.9e-11 44.4 10.5 0.02 15.4 0.8 7.9 7 0 0 7 7 7 3 Purple acid Phosphatase, N-terminal domain C2-set_2 PF08205.12 KFQ98101.1 - 6.3e-07 29.4 0.5 0.12 12.4 0.0 4.4 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.8 KFQ98101.1 - 5.1e-06 26.6 0.5 0.43 10.8 0.0 5.3 5 0 0 5 5 5 1 Natural killer cell receptor 2B4 fn3_2 PF16893.5 KFQ98101.1 - 0.00097 19.2 0.3 8.1 6.7 0.0 4.2 3 1 0 3 3 3 1 Fibronectin type III domain Cadherin-like PF12733.7 KFQ98101.1 - 0.065 13.8 0.9 24 5.5 0.1 3.7 3 0 0 3 3 3 0 Cadherin-like beta sandwich domain Izumo-Ig PF16706.5 KFQ98101.1 - 0.074 13.1 0.5 21 5.3 0.0 4.5 5 0 0 5 5 5 0 Izumo-like Immunoglobulin domain GBP_C PF02841.14 KFQ98101.1 - 3.2 7.1 7.6 5.1 6.4 7.6 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain RhoGEF PF00621.20 KFQ98102.1 - 2.7e-40 138.6 0.5 6.6e-40 137.3 0.5 1.7 1 0 0 1 1 1 1 RhoGEF domain GKAP PF03359.13 KFQ98103.1 - 3.3e-163 543.2 1.5 3.3e-163 543.2 1.5 2.6 2 0 0 2 2 2 1 Guanylate-kinase-associated protein (GKAP) protein Pollen_allerg_2 PF01620.16 KFQ98103.1 - 0.11 12.7 0.2 0.24 11.6 0.2 1.6 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) TDRP PF15683.5 KFQ98105.1 - 7.5e-74 246.6 7.9 8.3e-74 246.4 7.9 1.0 1 0 0 1 1 1 1 Testis development-related protein Elongin_A PF06881.11 KFQ98106.1 - 0.00024 21.6 0.1 0.00024 21.6 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box PF00646.33 KFQ98106.1 - 0.0034 17.2 0.1 0.017 15.0 0.0 2.3 2 0 0 2 2 2 1 F-box domain FAM110_C PF14160.6 KFQ98107.1 - 1.1e-35 123.0 0.7 1.1e-35 123.0 0.7 2.3 3 0 0 3 3 3 1 Centrosome-associated C terminus FAM110_N PF14161.6 KFQ98107.1 - 5.4e-24 84.5 0.6 1.7e-23 82.8 0.1 2.1 2 0 0 2 2 2 1 Centrosome-associated N terminus LMWPc PF01451.21 KFQ98108.1 - 3.8e-47 160.3 0.1 4.2e-47 160.1 0.1 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase TMEM206 PF15122.6 KFQ98108.1 - 0.026 13.7 0.1 0.036 13.2 0.1 1.1 1 0 0 1 1 1 0 TMEM206 protein family FAM150 PF15129.6 KFQ98109.1 - 3.8e-60 201.5 0.7 4.4e-60 201.3 0.7 1.0 1 0 0 1 1 1 1 FAM150 family TMEM18 PF14770.6 KFQ98110.1 - 3e-46 156.2 5.6 3.5e-46 156.0 5.6 1.0 1 0 0 1 1 1 1 Transmembrane protein 18 PDZ PF00595.24 KFQ98111.1 - 9.9e-17 61.1 1.2 1.7e-16 60.3 1.2 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFQ98111.1 - 9.9e-10 38.1 0.2 2.4e-09 36.9 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 KFQ98111.1 - 5.1e-07 30.1 0.0 0.045 14.2 0.0 2.7 2 1 0 2 2 2 2 PH domain PDZ_2 PF13180.6 KFQ98111.1 - 2.9e-05 24.3 0.1 7.4e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PH_17 PF18012.1 KFQ98111.1 - 8.1e-05 22.3 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 PH domain Tricorn_PDZ PF14685.6 KFQ98111.1 - 0.039 13.9 0.5 0.38 10.8 0.1 2.4 2 0 0 2 2 2 0 Tricorn protease PDZ domain An_peroxidase PF03098.15 KFQ98112.1 - 1.2e-185 618.1 0.0 1.5e-185 617.8 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase EGF_CA PF07645.15 KFQ98112.1 - 2.9e-09 37.0 6.2 2.9e-09 37.0 6.2 2.5 2 0 0 2 2 2 1 Calcium-binding EGF domain FXa_inhibition PF14670.6 KFQ98112.1 - 6.5e-06 26.3 6.8 6.5e-06 26.3 6.8 2.9 3 0 0 3 3 3 1 Coagulation Factor Xa inhibitory site Sushi PF00084.20 KFQ98112.1 - 1.1e-05 25.9 4.2 1.1e-05 25.9 4.2 2.2 2 0 0 2 2 2 1 Sushi repeat (SCR repeat) EGF_3 PF12947.7 KFQ98112.1 - 3.1e-05 24.1 6.3 3.1e-05 24.1 6.3 2.2 2 0 0 2 2 2 1 EGF domain cEGF PF12662.7 KFQ98112.1 - 0.00029 20.7 5.1 0.05 13.5 0.5 2.7 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF PF00008.27 KFQ98112.1 - 0.013 15.8 4.4 0.013 15.8 4.4 2.9 3 0 0 3 3 3 0 EGF-like domain Fibin PF15819.5 KFQ98112.1 - 0.065 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Fin bud initiation factor homologue DUF1682 PF07946.14 KFQ98112.1 - 0.18 11.0 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) hEGF PF12661.7 KFQ98112.1 - 1.6 9.5 7.4 0.22 12.2 1.5 2.7 2 0 0 2 2 2 0 Human growth factor-like EGF An_peroxidase PF03098.15 KFQ98113.1 - 4.2e-195 649.3 0.0 6.5e-195 648.7 0.0 1.3 1 0 0 1 1 1 1 Animal haem peroxidase I-set PF07679.16 KFQ98113.1 - 2e-87 287.4 0.5 1.2e-20 73.3 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ98113.1 - 2.8e-77 255.4 6.6 4.4e-20 72.1 0.2 4.7 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFQ98113.1 - 1.6e-50 169.3 3.3 9.7e-12 45.1 0.1 4.7 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 KFQ98113.1 - 8.8e-43 144.4 1.7 2.9e-13 49.8 0.1 4.7 4 0 0 4 4 4 4 Immunoglobulin domain LRR_8 PF13855.6 KFQ98113.1 - 2e-37 126.7 21.9 1.7e-17 62.9 3.6 3.7 1 1 2 3 3 3 3 Leucine rich repeat V-set PF07686.17 KFQ98113.1 - 3.6e-23 81.8 12.8 0.0007 19.7 0.2 8.2 4 4 1 5 5 5 5 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFQ98113.1 - 4.6e-19 68.3 2.7 0.001 19.1 0.0 4.7 4 0 0 4 4 4 4 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFQ98113.1 - 2.5e-16 59.9 0.0 0.0012 19.3 0.1 5.3 5 0 0 5 5 4 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain LRR_4 PF12799.7 KFQ98113.1 - 1.3e-15 57.3 21.3 1.2e-06 28.8 3.0 5.4 4 1 4 8 8 7 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFQ98113.1 - 6.3e-11 42.3 2.0 1.7e-09 37.7 0.1 2.6 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFQ98113.1 - 1.7e-10 40.7 2.5 3.3e-05 23.5 0.8 2.4 1 1 1 2 2 2 2 Leucine-rich repeat Ig_6 PF18452.1 KFQ98113.1 - 4.8e-10 38.8 0.0 0.45 10.1 0.0 4.8 4 0 0 4 4 4 3 Immunoglobulin domain Ig_4 PF16680.5 KFQ98113.1 - 8.6e-10 38.7 0.0 0.017 15.3 0.1 4.9 4 0 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain VWC PF00093.18 KFQ98113.1 - 5.5e-09 36.2 18.5 5.5e-09 36.2 18.5 2.9 3 0 0 3 3 2 1 von Willebrand factor type C domain Ig_C17orf99 PF17736.1 KFQ98113.1 - 1.8e-07 31.1 0.0 0.16 12.0 0.0 4.1 4 0 0 4 4 4 2 C17orf99 Ig domain Izumo-Ig PF16706.5 KFQ98113.1 - 1.9e-05 24.6 0.4 5.8 7.0 0.0 4.5 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain PSP94 PF05825.11 KFQ98113.1 - 0.0014 19.1 9.6 0.004 17.7 9.6 1.8 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) LRR_1 PF00560.33 KFQ98113.1 - 0.0015 18.8 9.8 9.6 7.2 0.2 5.6 4 0 0 4 4 4 0 Leucine Rich Repeat LRRCT PF01463.24 KFQ98113.1 - 0.0033 17.9 0.1 0.033 14.7 0.0 2.7 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain Amnionless PF14828.6 KFQ98113.1 - 0.0059 15.5 9.4 0.0099 14.8 9.4 1.2 1 0 0 1 1 1 1 Amnionless TILa PF12714.7 KFQ98113.1 - 0.0086 16.0 11.1 0.0086 16.0 11.1 2.2 2 0 0 2 2 1 1 TILa domain CFC PF09443.10 KFQ98113.1 - 0.1 12.4 4.2 0.37 10.7 4.2 2.0 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) DUF4618 PF15397.6 KFQ98113.1 - 0.18 11.2 1.2 0.35 10.3 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) fn1 PF00039.18 KFQ98113.1 - 1.6 9.0 6.3 6.8 7.0 6.3 2.2 1 0 0 1 1 1 0 Fibronectin type I domain MIS13 PF08202.11 KFQ98115.1 - 4.6e-27 95.1 2.7 9.5e-27 94.1 2.7 1.5 1 1 0 1 1 1 1 Mis12-Mtw1 protein family 7tm_1 PF00001.21 KFQ98116.1 - 1.1e-34 120.0 23.6 1.3e-34 119.7 23.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ98116.1 - 1.2e-11 44.4 23.2 1.5e-11 44.1 23.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFQ98116.1 - 0.0043 16.8 23.3 0.051 13.3 23.3 2.1 1 1 0 1 1 1 1 Olfactory receptor Rpr2 PF04032.16 KFQ98117.1 - 0.014 15.7 0.2 0.025 14.9 0.1 1.4 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain T4SS PF07996.11 KFQ98118.1 - 0.065 13.6 3.1 0.11 12.9 3.1 1.3 1 0 0 1 1 1 0 Type IV secretion system proteins MRP-S26 PF14943.6 KFQ98118.1 - 0.4 10.6 6.9 0.44 10.4 6.9 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Atg14 PF10186.9 KFQ98118.1 - 0.41 9.7 7.1 0.51 9.4 7.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 KFQ98118.1 - 0.48 10.5 10.4 3 7.9 10.4 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.19 KFQ98118.1 - 0.7 7.7 5.0 0.74 7.7 5.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Thioredoxin_8 PF13905.6 KFQ98120.1 - 1.4e-23 83.0 0.0 2.3e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KFQ98120.1 - 1.5e-05 24.7 0.0 2.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin TraF PF13728.6 KFQ98120.1 - 8e-05 22.6 0.1 0.0028 17.5 0.0 2.4 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 KFQ98120.1 - 0.00013 22.4 0.0 0.00031 21.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 KFQ98120.1 - 0.013 15.5 0.0 0.068 13.2 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin AhpC-TSA PF00578.21 KFQ98120.1 - 0.026 14.4 0.0 0.048 13.6 0.0 1.6 1 1 0 1 1 1 0 AhpC/TSA family CpXC PF14353.6 KFQ98120.1 - 0.029 14.4 0.0 0.083 12.9 0.0 1.8 1 1 0 1 1 1 0 CpXC protein AMP-binding PF00501.28 KFQ98121.1 - 1.1e-69 235.1 0.0 1.3e-69 234.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFQ98121.1 - 2.8e-06 28.2 0.1 5.7e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ank_2 PF12796.7 KFQ98126.1 - 4.9e-29 100.7 2.7 2.2e-15 57.0 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFQ98126.1 - 1.2e-26 91.9 6.3 8.4e-06 26.0 0.0 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KFQ98126.1 - 3.8e-26 91.1 2.8 2.6e-10 40.6 0.1 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ98126.1 - 1.4e-25 86.6 2.9 1.2e-05 25.3 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KFQ98126.1 - 1.4e-24 85.8 5.4 1.7e-09 37.7 0.1 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) CCDC144C PF14915.6 KFQ98127.1 - 1.4e-127 425.0 64.7 1.4e-127 425.0 64.7 5.7 3 2 2 5 5 5 1 CCDC144C protein coiled-coil region DUF3496 PF12001.8 KFQ98127.1 - 3e-23 82.3 2.8 3e-23 82.3 2.8 9.2 7 4 3 10 10 10 1 Domain of unknown function (DUF3496) Fib_alpha PF08702.10 KFQ98127.1 - 0.0013 19.0 10.1 0.0013 19.0 10.1 9.0 4 3 4 9 9 9 2 Fibrinogen alpha/beta chain family ZapB PF06005.12 KFQ98127.1 - 0.013 15.9 3.4 0.013 15.9 3.4 14.8 3 3 6 10 10 10 0 Cell division protein ZapB DUF4382 PF14321.6 KFQ98127.1 - 0.67 10.2 4.4 0.59 10.4 0.3 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4382) DUF3854 PF12965.7 KFQ98127.1 - 9.6 6.2 12.1 6.8 6.7 0.3 4.7 3 1 0 3 3 3 0 Domain of unknown function (DUF3854) DUF945 PF06097.11 KFQ98129.1 - 2.4e-08 33.5 0.0 0.44 9.6 0.0 6.5 1 1 0 2 2 2 2 Bacterial protein of unknown function (DUF945) DUF2993 PF11209.8 KFQ98129.1 - 5.8e-05 23.4 1.2 6.9 6.9 0.0 5.7 2 1 3 5 5 5 1 Protein of unknown function (DUF2993) DUF2125 PF09898.9 KFQ98129.1 - 0.074 12.7 0.0 7 6.2 0.0 3.4 1 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2125) Ntox37 PF15535.6 KFQ98129.1 - 0.58 10.6 10.2 17 6.0 0.7 6.0 4 1 1 5 5 5 0 Bacterial toxin 37 FKBP26_C PF18046.1 KFQ98129.1 - 3.4 7.8 13.4 96 3.2 0.0 7.4 8 1 1 9 9 9 0 FKBP26_C-terminal Glyco_transf_49 PF13896.6 KFQ98130.1 - 2.5e-56 191.4 0.0 2.8e-56 191.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan PT PF04886.12 KFQ98131.1 - 0.88 9.2 86.6 1.8e+04 -49.5 86.6 4.7 1 1 0 1 1 1 0 PT repeat Pkinase PF00069.25 KFQ98133.1 - 1.4e-63 214.8 0.9 1.4e-63 214.7 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ98133.1 - 1.9e-35 122.4 0.1 2.7e-35 121.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ98133.1 - 2.5e-10 40.1 0.1 3.3e-10 39.8 0.1 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFQ98133.1 - 0.00037 19.4 0.2 0.00087 18.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KFQ98133.1 - 0.0077 15.6 0.3 0.0077 15.6 0.3 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFQ98133.1 - 0.011 15.7 0.1 0.021 14.7 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Amidohydro_1 PF01979.20 KFQ98134.1 - 2.8e-37 128.8 0.1 3.4e-37 128.6 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFQ98134.1 - 1.9e-11 44.1 0.2 2.5e-05 23.9 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family HPS3_N PF14761.6 KFQ98134.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 JAKMIP_CC3 PF16034.5 KFQ98135.1 - 4.9e-80 268.2 15.8 4.9e-80 268.2 15.8 6.9 4 2 2 6 6 6 1 JAKMIP CC3 domain Coat_F PF07875.12 KFQ98135.1 - 0.52 10.6 5.3 0.1 12.9 0.5 2.5 2 0 0 2 2 2 0 Coat F domain BNIP3 PF06553.12 KFQ98136.1 - 5e-83 277.6 3.0 5.9e-83 277.3 3.0 1.0 1 0 0 1 1 1 1 BNIP3 SIR4_SID PF16991.5 KFQ98136.1 - 0.05 13.7 1.2 0.074 13.1 1.2 1.2 1 0 0 1 1 1 0 Sir4 SID domain WD40 PF00400.32 KFQ98137.1 - 1.1e-08 35.6 3.6 5.1 8.1 0.1 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ98137.1 - 0.00048 20.4 0.0 18 5.7 0.0 4.6 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Y_phosphatase2 PF03162.13 KFQ98137.1 - 0.0093 15.6 0.3 0.59 9.7 0.0 2.4 2 0 0 2 2 2 2 Tyrosine phosphatase family Exo_endo_phos PF03372.23 KFQ98138.1 - 5.1e-17 62.2 0.0 6.6e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family OLF PF02191.16 KFQ98138.1 - 0.047 13.2 1.3 0.084 12.4 1.3 1.3 1 0 0 1 1 1 0 Olfactomedin-like domain Homeodomain PF00046.29 KFQ98139.1 - 0.00066 19.5 3.3 0.0012 18.6 3.3 1.4 1 0 0 1 1 1 1 Homeodomain 7tm_1 PF00001.21 KFQ98140.1 - 3.7e-46 157.6 11.7 4.4e-46 157.3 11.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ98140.1 - 2.5e-07 30.3 10.3 3e-07 30.1 10.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 KFQ98140.1 - 7.4e-07 28.8 4.0 7.4e-07 28.8 4.0 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.9 KFQ98140.1 - 2.6e-06 26.9 9.0 2.2e-05 23.9 8.9 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 KFQ98140.1 - 6.6e-05 22.8 8.9 0.00033 20.5 8.9 1.9 1 1 0 1 1 1 1 Olfactory receptor AA_kinase PF00696.28 KFQ98142.1 - 2.3e-41 142.0 0.4 4.6e-41 141.0 0.4 1.5 1 0 0 1 1 1 1 Amino acid kinase family Aldedh PF00171.22 KFQ98142.1 - 2.8e-08 32.7 0.2 0.081 11.4 0.0 3.2 3 0 0 3 3 3 3 Aldehyde dehydrogenase family Pkinase_Tyr PF07714.17 KFQ98151.1 - 1.9e-77 260.1 0.0 3e-77 259.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.24 KFQ98151.1 - 3.3e-52 175.3 0.0 6e-28 97.2 0.0 2.3 2 0 0 2 2 2 2 Receptor L domain GF_recep_IV PF14843.6 KFQ98151.1 - 1.7e-40 137.8 30.2 1.7e-40 137.8 30.2 4.2 3 1 0 3 3 3 2 Growth factor receptor domain IV Pkinase PF00069.25 KFQ98151.1 - 5.3e-29 101.4 0.0 8.6e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.20 KFQ98151.1 - 4.3e-17 62.4 67.9 2.1e-12 47.2 12.2 5.1 3 1 2 5 5 5 4 Furin-like cysteine rich region Adeno_E3_CR2 PF02439.15 KFQ98151.1 - 0.0058 16.4 0.1 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 KFQ98151.1 - 0.0091 16.9 0.1 0.021 15.7 0.1 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 KFQ98151.1 - 0.0093 16.0 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 1 Protocadherin TMEM154 PF15102.6 KFQ98151.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Anoctamin PF04547.12 KFQ98170.1 - 5.1e-125 417.8 23.3 6e-125 417.6 23.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF898 PF05987.13 KFQ98170.1 - 3 6.8 12.0 0.023 13.7 2.1 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF898) Abhydrolase_1 PF00561.20 KFQ98171.1 - 7.4e-21 74.9 0.0 2.5e-20 73.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFQ98171.1 - 1.6e-16 61.6 0.0 2.1e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFQ98171.1 - 1.5e-12 47.3 0.0 2.2e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KFQ98171.1 - 0.00097 17.9 0.0 0.0026 16.5 0.0 1.6 2 0 0 2 2 2 1 Ndr family Abhydrolase_3 PF07859.13 KFQ98171.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1071 PF06378.11 KFQ98171.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) PAF-AH_p_II PF03403.13 KFQ98171.1 - 0.14 10.6 0.0 0.26 9.7 0.0 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF4461 PF14688.6 KFQ98172.1 - 6e-123 410.6 0.8 8.9e-123 410.0 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4461) DUF4460 PF14687.6 KFQ98172.1 - 5.4e-39 132.7 0.1 1.8e-38 131.0 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) YkyA PF10368.9 KFQ98172.1 - 0.07 12.8 1.0 0.21 11.2 1.0 1.8 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein ApoB100_C PF12491.8 KFQ98172.1 - 0.092 12.7 1.1 0.27 11.3 0.1 2.2 2 0 0 2 2 2 0 Apolipoprotein B100 C terminal TPR_1 PF00515.28 KFQ98173.1 - 6.5e-15 54.2 15.3 2.1e-05 24.2 0.1 7.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ98173.1 - 1.5e-13 49.7 25.6 0.00097 19.1 0.0 9.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ98173.1 - 3.5e-08 33.6 16.4 0.024 14.9 0.3 7.4 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ98173.1 - 3.6e-06 27.4 18.1 1.5 9.4 0.0 9.0 8 2 2 10 10 10 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ98173.1 - 4.1e-06 26.6 12.1 0.001 19.1 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ98173.1 - 1.2e-05 25.0 2.1 0.024 14.6 0.0 5.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ98173.1 - 1.5e-05 25.4 5.2 12 7.1 0.0 7.4 8 1 1 9 9 8 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KFQ98173.1 - 2.4e-05 24.3 4.1 0.059 13.4 0.3 3.7 3 1 0 3 3 3 2 Putative TPR-like repeat TPR_17 PF13431.6 KFQ98173.1 - 0.00065 19.9 11.1 4.7 7.8 0.1 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ98173.1 - 0.001 18.9 2.9 1.3 9.0 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ98173.1 - 0.0019 18.4 25.5 3.1 8.1 0.4 7.5 7 2 0 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 KFQ98173.1 - 0.015 14.7 4.4 1 8.7 0.0 3.0 3 0 0 3 3 3 0 MalT-like TPR region TPR_16 PF13432.6 KFQ98173.1 - 0.03 15.0 0.2 5.3 7.8 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat BLOC1_2 PF10046.9 KFQ98173.1 - 0.08 13.2 2.9 0.57 10.5 2.9 2.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 KFQ98173.1 - 0.23 11.7 1.3 0.89 9.9 0.6 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TPR_6 PF13174.6 KFQ98173.1 - 0.56 11.0 8.1 28 5.6 0.0 6.0 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ98173.1 - 0.76 9.5 5.3 8.7 6.1 0.0 4.8 5 0 0 5 5 5 0 TPR repeat DLIC PF05783.11 KFQ98174.1 - 2e-245 815.0 0.0 2.3e-245 814.7 0.0 1.0 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) Roc PF08477.13 KFQ98174.1 - 0.04 14.1 0.1 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MARVEL PF01284.23 KFQ98176.1 - 5.2e-09 36.3 15.2 1e-08 35.3 15.2 1.5 1 1 0 1 1 1 1 Membrane-associating domain PhoR PF11808.8 KFQ98176.1 - 9.4 6.7 8.7 38 4.8 0.2 2.6 1 1 1 2 2 2 0 Phosphate regulon sensor protein PhoR MARVEL PF01284.23 KFQ98177.1 - 1.1e-18 67.7 18.3 1.2e-18 67.5 18.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain Retrotran_gag_3 PF14244.6 KFQ98177.1 - 0.33 10.8 1.4 0.35 10.7 0.1 1.6 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type TMEM138 PF14935.6 KFQ98177.1 - 1.7 9.3 13.5 5.4 7.7 6.0 2.1 1 1 1 2 2 2 0 Transmembrane protein 138 HRG PF16954.5 KFQ98177.1 - 3.9 7.9 19.7 0.41 11.1 6.7 3.2 2 1 1 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene NAD_Gly3P_dh_C PF07479.14 KFQ98178.1 - 2.3e-50 170.6 0.4 4.5e-50 169.6 0.4 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KFQ98178.1 - 8.5e-46 155.8 0.4 1.7e-45 154.8 0.1 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Oxysterol_BP PF01237.18 KFQ98179.1 - 1.4e-84 284.1 4.7 9.8e-83 278.0 4.7 2.2 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 KFQ98179.1 - 7.3e-08 32.6 0.0 1.3e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFQ98179.1 - 8.5e-07 29.4 0.0 2.9e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 PH domain PH_6 PF15406.6 KFQ98179.1 - 0.018 15.3 0.0 0.056 13.7 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain PH_16 PF17838.1 KFQ98179.1 - 0.14 12.0 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 PH domain Pyridoxal_deC PF00282.19 KFQ98180.1 - 2.4e-115 385.2 0.0 2.8e-115 385.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KFQ98180.1 - 2.1e-06 26.9 0.0 1.6e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFQ98180.1 - 0.00013 21.4 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 KFQ98180.1 - 0.075 11.7 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS ecTbetaR2 PF08917.10 KFQ98181.1 - 2.4e-42 143.3 17.1 6.6e-42 141.9 17.1 1.7 1 0 0 1 1 1 1 Transforming growth factor beta receptor 2 ectodomain Pkinase_Tyr PF07714.17 KFQ98181.1 - 6.7e-36 123.9 0.0 1.2e-35 123.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ98181.1 - 1.2e-33 116.6 0.0 2.1e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KFQ98181.1 - 0.013 14.2 0.0 0.028 13.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KFQ98181.1 - 0.02 14.8 0.1 0.033 14.1 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFQ98181.1 - 0.025 13.5 0.7 0.17 10.8 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain FixQ PF05545.11 KFQ98181.1 - 0.073 13.1 0.1 0.24 11.4 0.1 1.8 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Sigma_reg_N PF13800.6 KFQ98181.1 - 0.17 12.2 0.2 0.42 10.9 0.2 1.6 1 0 0 1 1 1 0 Sigma factor regulator N-terminal RRM_1 PF00076.22 KFQ98182.1 - 7.3e-19 67.4 0.1 1.9e-13 50.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TBD PF12845.7 KFQ98183.1 - 1.6e-17 63.1 4.5 3.3e-16 58.9 0.1 3.6 3 0 0 3 3 3 1 TBD domain Cob_adeno_trans PF01923.18 KFQ98183.1 - 0.056 13.6 3.5 0.14 12.3 3.5 1.7 1 0 0 1 1 1 0 Cobalamin adenosyltransferase VASP_tetra PF08776.11 KFQ98183.1 - 0.059 13.0 4.3 0.19 11.4 4.3 1.9 1 0 0 1 1 1 0 VASP tetramerisation domain Speriolin_N PF15058.6 KFQ98183.1 - 0.068 13.3 1.6 0.15 12.2 1.6 1.7 1 0 0 1 1 1 0 Speriolin N terminus DUF1515 PF07439.11 KFQ98183.1 - 0.78 9.8 6.3 0.08 13.0 0.5 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) RRM_Rrp7 PF17799.1 KFQ98183.1 - 2 8.2 8.3 2.4 7.9 5.3 2.6 2 1 1 3 3 3 0 Rrp7 RRM-like N-terminal domain FUSC-like PF12805.7 KFQ98183.1 - 2.6 7.0 7.1 4.1 6.4 7.1 1.4 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Prefoldin_2 PF01920.20 KFQ98183.1 - 8.7 6.4 34.1 3.3 7.7 5.4 4.1 3 1 1 4 4 4 0 Prefoldin subunit Cmc1 PF08583.10 KFQ98184.1 - 5.2e-16 58.4 4.4 6.9e-16 58.0 4.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Colipase PF01114.18 KFQ98184.1 - 0.017 14.7 1.3 0.029 14.0 1.3 1.3 1 0 0 1 1 1 0 Colipase, N-terminal domain NDUF_B7 PF05676.13 KFQ98184.1 - 0.028 14.1 1.4 0.028 14.1 1.4 2.0 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) GCK PF07802.11 KFQ98184.1 - 0.18 12.2 4.9 0.31 11.5 4.8 1.5 1 1 0 1 1 1 0 GCK domain CHCH PF06747.13 KFQ98184.1 - 1.3 9.2 8.6 6.9 6.9 1.6 2.6 3 0 0 3 3 3 0 CHCH domain T-box_assoc PF16176.5 KFQ98185.1 - 5.9e-109 363.4 2.6 7.6e-109 363.1 2.6 1.1 1 0 0 1 1 1 1 T-box transcription factor-associated T-box PF00907.22 KFQ98185.1 - 9.6e-63 211.8 0.2 1.6e-62 211.0 0.2 1.4 1 0 0 1 1 1 1 T-box HCO3_cotransp PF00955.21 KFQ98186.1 - 1.7e-243 809.0 9.8 2.1e-243 808.7 9.8 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 KFQ98186.1 - 2.4e-107 358.7 0.0 3.5e-107 358.2 0.0 1.2 1 0 0 1 1 1 1 Band 3 cytoplasmic domain MFS_MOT1 PF16983.5 KFQ98186.1 - 0.64 10.4 6.0 0.51 10.8 1.5 3.2 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily Pkinase PF00069.25 KFQ98187.1 - 2.8e-30 105.6 1.1 2.8e-30 105.6 1.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ98187.1 - 1.4e-21 77.0 0.2 2.4e-21 76.2 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFQ98187.1 - 0.00015 21.8 0.2 0.0011 19.0 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Arm PF00514.23 KFQ98187.1 - 0.00035 20.5 10.5 0.023 14.7 0.2 4.5 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Pkinase_fungal PF17667.1 KFQ98187.1 - 0.00054 18.8 1.1 0.002 16.9 0.0 2.2 3 0 0 3 3 3 1 Fungal protein kinase RIO1 PF01163.22 KFQ98187.1 - 0.00079 19.1 0.1 0.0021 17.7 0.1 1.6 1 1 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KFQ98187.1 - 0.0083 15.1 2.0 0.018 14.0 2.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain LRR_8 PF13855.6 KFQ98188.1 - 2.2e-17 62.5 3.3 1.7e-11 43.7 0.2 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRRNT PF01462.18 KFQ98188.1 - 6.2e-09 35.3 3.0 6.2e-09 35.3 3.0 2.1 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.7 KFQ98188.1 - 5.5e-08 33.0 8.5 2.5e-05 24.5 0.6 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFQ98188.1 - 2.7e-06 27.4 0.1 4.3e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KFQ98188.1 - 0.00029 20.6 2.2 0.2 11.8 0.0 3.5 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 KFQ98188.1 - 0.00038 20.6 8.3 0.23 12.1 0.2 4.4 4 2 0 4 4 4 2 Leucine Rich Repeat ketoacyl-synt PF00109.26 KFQ98189.1 - 1.4e-55 188.7 4.6 1.6e-55 188.5 2.2 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KFQ98189.1 - 2.9e-38 130.5 0.1 5.9e-38 129.5 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KFQ98189.1 - 1.2e-05 24.8 0.1 6.5e-05 22.4 0.1 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KFQ98189.1 - 0.083 13.3 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension PAW PF04721.17 KFQ98190.1 - 5.5e-74 248.2 0.6 5.5e-74 248.2 0.6 1.6 2 0 0 2 2 2 1 PNGase C-terminal domain, mannose-binding module PAW PUB PF09409.10 KFQ98190.1 - 2.4e-16 59.4 0.0 9.1e-16 57.6 0.0 2.1 1 0 0 1 1 1 1 PUB domain Transglut_core PF01841.19 KFQ98190.1 - 3e-14 53.4 0.6 6.7e-14 52.3 0.6 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 KFQ98190.1 - 8.1e-11 41.8 0.5 1.5e-10 40.9 0.5 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain TSC22 PF01166.18 KFQ98190.1 - 0.69 10.3 4.9 2.5 8.5 0.1 2.8 2 1 0 2 2 2 0 TSC-22/dip/bun family DNA_topoisoIV PF00521.20 KFQ98191.1 - 7e-134 446.9 0.3 1.3e-133 446.0 0.0 1.6 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KFQ98191.1 - 2.4e-49 166.9 4.5 2.4e-49 166.9 4.5 2.6 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DTHCT PF08070.11 KFQ98191.1 - 4.3e-27 94.9 17.5 4.3e-27 94.9 17.5 6.6 4 1 2 6 6 6 1 DTHCT (NUC029) region DNA_gyraseB PF00204.25 KFQ98191.1 - 1.1e-25 90.1 1.0 2.8e-25 88.8 1.0 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KFQ98191.1 - 3.6e-15 56.4 0.0 1.5e-14 54.5 0.0 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KFQ98191.1 - 3.7e-09 36.7 0.1 1.6e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 Toprim domain Hormone_recep PF00104.30 KFQ98192.1 - 1.1e-13 51.2 0.3 2.3e-13 50.2 0.0 1.6 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFQ98193.1 - 3.8e-34 117.0 16.3 4.4e-34 116.8 16.3 1.0 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Class_IIIsignal PF04021.12 KFQ98194.1 - 0.65 10.1 0.2 0.65 10.1 0.2 2.1 2 0 0 2 2 2 0 Class III signal peptide zf-C4 PF00105.18 KFQ98197.1 - 2.2e-30 104.9 15.9 4.1e-30 104.0 15.9 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFQ98197.1 - 6.2e-17 61.9 0.0 2.4e-16 59.9 0.0 1.9 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFQ98198.1 - 3.1e-31 107.6 15.9 7.2e-31 106.5 15.9 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFQ98198.1 - 3.7e-25 88.7 0.3 1.1e-24 87.2 0.3 1.8 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor LpxD PF04613.14 KFQ98198.1 - 0.037 13.8 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Ribosomal_L15e PF00827.17 KFQ98199.1 - 4.7e-98 326.5 3.7 5.4e-98 326.3 3.7 1.0 1 0 0 1 1 1 1 Ribosomal L15 Hepatitis_core PF00906.20 KFQ98199.1 - 2 7.9 7.6 0.14 11.7 0.3 2.0 2 0 0 2 2 2 0 Hepatitis core antigen Ras PF00071.22 KFQ98200.1 - 9.8e-27 93.5 0.4 1.1e-26 93.3 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ98200.1 - 8.6e-12 45.3 0.0 1.6e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ98200.1 - 1.8e-09 37.3 0.3 2.4e-09 36.9 0.3 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFQ98200.1 - 1.4e-06 28.4 0.0 2.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFQ98200.1 - 0.00037 20.1 1.7 0.08 12.5 1.7 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFQ98200.1 - 0.0019 18.1 0.6 0.12 12.2 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KFQ98200.1 - 0.0064 16.6 0.7 0.46 10.5 0.0 2.7 2 1 1 3 3 3 1 Dynamin family AAA_14 PF13173.6 KFQ98200.1 - 0.0094 16.0 0.2 0.041 13.9 0.2 1.9 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 KFQ98200.1 - 0.013 15.1 2.8 0.47 10.0 0.3 2.1 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 KFQ98200.1 - 0.028 14.8 0.3 0.34 11.3 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PRORP PF16953.5 KFQ98200.1 - 0.031 13.8 0.0 0.037 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein-only RNase P AAA_24 PF13479.6 KFQ98200.1 - 0.054 13.2 0.1 0.084 12.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain DUF4288 PF14119.6 KFQ98200.1 - 0.065 13.6 0.1 0.14 12.6 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4288) FeoB_N PF02421.18 KFQ98200.1 - 0.068 12.7 0.1 0.14 11.7 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF1057 PF06342.12 KFQ98200.1 - 0.095 11.7 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) AAA_22 PF13401.6 KFQ98200.1 - 0.16 12.2 0.7 1.1 9.5 0.1 2.2 1 1 0 2 2 2 0 AAA domain UQ_con PF00179.26 KFQ98201.1 - 2.1e-43 147.3 0.0 2.3e-43 147.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFQ98201.1 - 0.0017 18.1 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KFQ98201.1 - 0.0098 16.2 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KFQ98201.1 - 0.095 12.6 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 UEV domain UQ_con PF00179.26 KFQ98202.1 - 1.4e-43 147.9 0.0 1.5e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFQ98202.1 - 0.00064 19.4 0.0 0.00079 19.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KFQ98202.1 - 0.016 15.5 0.0 0.022 15.0 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 KFQ98202.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 UEV domain DUF4462 PF14692.6 KFQ98205.1 - 0.078 12.5 0.5 0.48 9.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) zf-met PF12874.7 KFQ98206.1 - 1.6e-08 34.7 0.7 3.4e-08 33.6 0.7 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFQ98206.1 - 0.00025 21.2 0.7 0.00025 21.2 0.7 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFQ98207.1 - 3.4e-21 74.9 16.9 3.2e-08 33.7 2.4 3.6 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFQ98207.1 - 9.8e-18 64.0 14.2 1.7e-06 28.2 3.2 3.3 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFQ98207.1 - 1.1e-07 32.2 6.7 0.017 15.5 0.1 3.2 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.12 KFQ98207.1 - 1e-06 29.1 9.0 0.16 12.2 0.6 3.2 3 0 0 3 3 3 3 A-kinase anchoring protein 95 (AKAP95) zf-U1 PF06220.12 KFQ98207.1 - 1.4e-06 28.0 6.6 0.06 13.1 0.0 3.3 3 0 0 3 3 3 2 U1 zinc finger zf-C2H2_4 PF13894.6 KFQ98207.1 - 0.0034 18.1 5.3 1.4 10.0 0.6 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KFQ98207.1 - 0.0065 16.9 11.0 2 9.0 2.0 3.6 3 0 0 3 3 3 1 Zinc finger, C2H2 type OrfB_Zn_ribbon PF07282.11 KFQ98207.1 - 0.0086 16.0 5.5 0.19 11.7 0.7 3.4 3 0 0 3 3 3 1 Putative transposase DNA-binding domain zf_C2H2_ZHX PF18387.1 KFQ98207.1 - 0.011 15.3 4.1 1.2 8.9 0.3 2.5 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF3449 PF11931.8 KFQ98207.1 - 0.028 14.2 7.3 0.31 10.8 1.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3449) zf-C2H2_9 PF16293.5 KFQ98207.1 - 0.031 14.1 5.3 4.3 7.3 0.3 3.4 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-Sec23_Sec24 PF04810.15 KFQ98207.1 - 0.038 14.0 3.4 16 5.7 0.1 3.4 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger zf-DBF PF07535.12 KFQ98207.1 - 0.059 13.5 8.5 0.088 12.9 0.9 3.3 3 0 0 3 3 3 0 DBF zinc finger UPF0728 PF15092.6 KFQ98207.1 - 0.06 13.2 0.1 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0728 DUF4187 PF13821.6 KFQ98207.1 - 0.087 12.6 0.0 2.5 8.0 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4187) zinc_ribbon_15 PF17032.5 KFQ98207.1 - 0.52 11.1 6.2 18 6.2 0.1 2.9 2 1 2 4 4 4 0 zinc-ribbon family DUF493 PF04359.14 KFQ98207.1 - 4.4 7.9 5.4 8 7.1 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF493) PHD_2 PF13831.6 KFQ98207.1 - 8.2 6.1 6.9 9.1 5.9 0.2 3.0 3 0 0 3 3 3 0 PHD-finger zf-BED PF02892.15 KFQ98207.1 - 8.3 6.5 8.4 5.8 7.0 0.1 2.7 3 0 0 3 3 3 0 BED zinc finger PCAF_N PF06466.11 KFQ98208.1 - 8.7e-104 346.5 1.1 1.4e-103 345.9 1.1 1.3 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain PF00439.25 KFQ98208.1 - 3.6e-25 87.8 0.4 8.5e-25 86.6 0.4 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KFQ98208.1 - 3.7e-10 40.1 0.0 8.6e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFQ98208.1 - 1.6e-07 31.3 0.0 3.3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFQ98208.1 - 6.7e-06 26.4 0.2 1.4e-05 25.4 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFQ98208.1 - 0.11 12.6 0.1 0.3 11.2 0.1 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PP2C PF00481.21 KFQ98209.1 - 7.9e-29 101.1 0.1 1.4e-23 83.9 0.0 3.5 3 1 1 4 4 4 2 Protein phosphatase 2C Ras PF00071.22 KFQ98210.1 - 3.1e-63 212.2 0.3 3.6e-63 212.0 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ98210.1 - 7.5e-36 123.0 0.1 1.5e-35 122.0 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ98210.1 - 1e-12 47.9 0.0 1.2e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFQ98210.1 - 2.2e-05 23.9 0.0 2.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFQ98210.1 - 5.4e-05 23.3 0.0 8.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFQ98210.1 - 0.0004 20.3 0.3 0.36 10.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFQ98210.1 - 0.0018 17.9 0.0 0.0052 16.4 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFQ98210.1 - 0.013 15.9 0.1 0.021 15.2 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain MCR_beta PF02241.18 KFQ98210.1 - 0.019 14.6 0.2 0.025 14.2 0.2 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain BrnT_toxin PF04365.13 KFQ98210.1 - 0.061 13.7 0.1 0.46 10.8 0.0 2.1 2 0 0 2 2 2 0 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system EF-hand_7 PF13499.6 KFQ98211.1 - 1.2e-10 41.6 6.0 1.2e-10 41.6 6.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFQ98211.1 - 1.8e-10 39.6 6.9 8.2e-06 25.0 0.3 2.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFQ98211.1 - 3.1e-10 39.1 5.3 9.3e-06 25.2 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFQ98211.1 - 2e-06 27.0 4.1 0.00052 19.4 0.1 2.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KFQ98211.1 - 6.5e-05 22.7 6.4 0.00028 20.7 5.4 2.2 1 1 1 2 2 2 2 EF-hand domain pair DUF5580 PF17743.1 KFQ98211.1 - 0.00021 20.0 0.2 0.00033 19.3 0.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SPARC_Ca_bdg PF10591.9 KFQ98211.1 - 0.0013 19.0 0.8 0.0034 17.7 0.8 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KFQ98211.1 - 0.042 13.7 4.7 0.25 11.3 1.3 2.7 2 1 0 2 2 2 0 EF hand EF-hand_4 PF12763.7 KFQ98211.1 - 0.1 12.5 1.5 0.44 10.5 0.6 2.2 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF4483 PF14825.6 KFQ98211.1 - 0.12 12.1 0.0 1.2 8.9 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4483) Ion_trans PF00520.31 KFQ98212.1 - 6.9e-33 113.9 13.2 1e-32 113.3 13.2 1.2 1 0 0 1 1 1 1 Ion transport protein PAS_9 PF13426.7 KFQ98212.1 - 2.6e-18 66.2 0.0 1e-17 64.3 0.0 2.0 2 0 0 2 2 2 1 PAS domain Ion_trans_2 PF07885.16 KFQ98212.1 - 8.6e-11 41.7 0.6 8.6e-11 41.7 0.6 2.9 3 0 0 3 3 3 1 Ion channel cNMP_binding PF00027.29 KFQ98212.1 - 1.3e-09 38.0 0.0 3.1e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PAS_3 PF08447.12 KFQ98212.1 - 1e-07 32.2 0.0 2.1e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KFQ98212.1 - 4.4e-05 23.7 0.0 0.00053 20.2 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 KFQ98212.1 - 5.1e-05 23.2 0.0 0.00013 21.9 0.0 1.7 1 0 0 1 1 1 1 PAS fold CENP-F_leu_zip PF10473.9 KFQ98212.1 - 0.00089 19.3 3.1 0.23 11.5 1.8 2.7 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2959 PF11172.8 KFQ98212.1 - 0.034 14.3 0.6 0.07 13.3 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) BAR_3 PF16746.5 KFQ98212.1 - 0.037 13.7 0.6 0.088 12.5 0.6 1.6 1 0 0 1 1 1 0 BAR domain of APPL family SlyX PF04102.12 KFQ98212.1 - 0.054 14.1 0.7 0.15 12.7 0.7 1.7 1 0 0 1 1 1 0 SlyX LPP PF04728.13 KFQ98212.1 - 0.078 13.4 0.9 0.24 11.8 0.9 1.7 1 0 0 1 1 1 0 Lipoprotein leucine-zipper RsgA_GTPase PF03193.16 KFQ98212.1 - 0.081 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase Seryl_tRNA_N PF02403.22 KFQ98212.1 - 0.098 12.9 0.8 0.23 11.7 0.8 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TMF_DNA_bd PF12329.8 KFQ98212.1 - 9.5 6.3 8.4 5.9 7.0 1.3 2.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding RabGAP-TBC PF00566.18 KFQ98214.1 - 6.5e-27 94.6 12.4 3e-25 89.1 12.4 3.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PI-PLC-X PF00388.19 KFQ98215.1 - 2.9e-61 205.3 0.1 6e-61 204.3 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFQ98215.1 - 6.2e-39 132.9 0.2 1.7e-38 131.5 0.2 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain PH_12 PF16457.5 KFQ98215.1 - 1.8e-21 77.0 0.2 7.8e-21 75.0 0.1 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain EF-hand_like PF09279.11 KFQ98215.1 - 3.5e-17 62.7 0.0 8e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 KFQ98215.1 - 1.3e-16 60.8 0.0 3e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain PH_14 PF17787.1 KFQ98215.1 - 4.6e-06 26.5 0.1 1.2e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 PH domain PH PF00169.29 KFQ98215.1 - 4.7e-05 23.9 0.1 0.00015 22.3 0.1 2.0 1 0 0 1 1 1 1 PH domain Mcp5_PH PF12814.7 KFQ98215.1 - 0.00027 21.0 0.0 0.00065 19.8 0.0 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology RRM_1 PF00076.22 KFQ98216.1 - 2.8e-14 52.7 0.4 4.4e-14 52.1 0.4 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFQ98216.1 - 0.00074 19.6 0.7 0.004 17.2 0.1 2.4 2 1 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 KFQ98216.1 - 0.0069 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Raftlin PF15250.6 KFQ98217.1 - 1.2e-223 743.1 1.4 1.5e-223 742.8 1.4 1.1 1 0 0 1 1 1 1 Raftlin PilO PF04350.13 KFQ98217.1 - 0.083 13.0 3.1 0.11 12.6 0.0 2.3 2 0 0 2 2 2 0 Pilus assembly protein, PilO NAD_binding_1 PF00175.21 KFQ98218.1 - 1.3e-13 51.5 0.0 2.4e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KFQ98218.1 - 6e-07 29.7 0.0 1.8e-05 24.9 0.0 2.3 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Ank_2 PF12796.7 KFQ98219.1 - 2.1e-163 531.4 69.4 7.5e-18 64.9 0.2 14.0 3 3 14 17 17 17 17 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ98219.1 - 1e-153 497.9 47.2 8.6e-15 54.9 0.8 20.7 7 3 15 22 22 22 22 Ankyrin repeats (many copies) Ank PF00023.30 KFQ98219.1 - 5.9e-143 459.7 75.4 6.6e-07 29.5 0.1 27.9 28 0 0 28 28 28 26 Ankyrin repeat Ank_3 PF13606.6 KFQ98219.1 - 2.7e-118 371.4 52.1 6.5e-06 26.1 0.1 28.2 28 0 0 28 28 28 27 Ankyrin repeat Ank_5 PF13857.6 KFQ98219.1 - 1.2e-117 382.4 58.1 9.8e-10 38.5 0.1 21.4 5 4 19 24 24 24 22 Ankyrin repeats (many copies) CN_hydrolase PF00795.22 KFQ98220.1 - 2.4e-16 59.9 0.0 3.5e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Collagen PF01391.18 KFQ98221.1 - 4.8e-29 99.9 98.7 2.6e-09 36.7 29.6 4.6 1 1 3 4 4 4 4 Collagen triple helix repeat (20 copies) DUF4215 PF13948.6 KFQ98221.1 - 0.00013 22.4 5.7 0.00013 22.4 5.7 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF4215) GLTP PF08718.11 KFQ98222.1 - 1.2e-42 145.7 0.0 2.5e-42 144.7 0.0 1.6 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) PH PF00169.29 KFQ98222.1 - 5.3e-08 33.3 0.0 1.5e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFQ98222.1 - 6e-05 23.3 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFQ98222.1 - 0.014 15.8 0.0 0.31 11.5 0.0 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain FKBP_C PF00254.28 KFQ98223.1 - 2e-22 79.3 0.0 3.6e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_7 PF13499.6 KFQ98223.1 - 2.2e-07 31.2 3.0 3.4e-07 30.6 3.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFQ98223.1 - 1.3e-06 27.8 2.8 0.022 14.6 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFQ98223.1 - 1.2e-05 24.6 2.4 0.041 13.4 1.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 KFQ98223.1 - 3.5e-05 23.0 6.0 0.0077 15.7 1.4 2.8 3 0 0 3 3 3 2 EF hand Peptidase_C69 PF03577.15 KFQ98224.1 - 2.9e-09 36.4 0.0 4.5e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C69 AAT PF03417.16 KFQ98224.1 - 0.059 13.0 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase WH2 PF02205.20 KFQ98225.1 - 9.7e-10 38.0 0.9 1.9e-09 37.0 0.9 1.6 1 0 0 1 1 1 1 WH2 motif RhoGAP PF00620.27 KFQ98226.1 - 9.9e-51 171.6 0.0 2.2e-50 170.4 0.0 1.5 2 0 0 2 2 2 1 RhoGAP domain C1_1 PF00130.22 KFQ98226.1 - 1.5e-16 60.0 7.0 2.6e-16 59.3 7.0 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH2 PF00017.24 KFQ98226.1 - 5.6e-12 45.6 0.1 2e-11 43.8 0.0 2.0 2 0 0 2 2 2 1 SH2 domain zf-RING-like PF08746.11 KFQ98226.1 - 0.061 13.6 5.0 0.14 12.5 5.0 1.6 1 0 0 1 1 1 0 RING-like domain PHD_2 PF13831.6 KFQ98226.1 - 0.12 12.0 2.3 0.26 10.9 2.3 1.5 1 0 0 1 1 1 0 PHD-finger C1_2 PF03107.16 KFQ98226.1 - 0.22 11.9 3.0 0.54 10.6 3.0 1.7 1 0 0 1 1 1 0 C1 domain FYVE_2 PF02318.16 KFQ98226.1 - 1.8 8.8 9.2 1.6 9.0 7.1 2.0 1 1 1 2 2 2 0 FYVE-type zinc finger PHD PF00628.29 KFQ98226.1 - 7 6.6 9.1 15 5.6 9.1 1.5 1 0 0 1 1 1 0 PHD-finger bZIP_1 PF00170.21 KFQ98227.1 - 7.7e-13 48.3 8.5 1.4e-12 47.5 8.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFQ98227.1 - 5.1e-10 39.3 8.3 5.1e-10 39.3 8.3 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFQ98227.1 - 4.6e-05 23.9 5.1 0.00014 22.3 5.1 1.8 1 0 0 1 1 1 1 bZIP Maf transcription factor ZapB PF06005.12 KFQ98227.1 - 0.0094 16.4 2.7 0.0094 16.4 2.7 1.7 2 0 0 2 2 1 1 Cell division protein ZapB TolA_bind_tri PF16331.5 KFQ98227.1 - 0.023 14.8 3.1 0.023 14.8 3.1 2.4 3 0 0 3 3 3 0 TolA binding protein trimerisation NDUFB11 PF17250.2 KFQ98227.1 - 0.14 12.8 2.5 0.14 12.8 0.9 1.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase 11 kDa subunit GIT_CC PF16559.5 KFQ98227.1 - 0.17 11.8 5.0 0.48 10.3 5.0 1.8 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Zip PF02535.22 KFQ98227.1 - 0.2 10.8 8.8 0.3 10.3 8.8 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DivIC PF04977.15 KFQ98227.1 - 0.49 10.2 3.1 0.96 9.3 3.1 1.4 1 0 0 1 1 1 0 Septum formation initiator Cnn_1N PF07989.11 KFQ98227.1 - 3.3 7.9 7.5 0.25 11.5 2.4 1.7 2 0 0 2 2 1 0 Centrosomin N-terminal motif 1 TAP42 PF04177.12 KFQ98227.1 - 3.7 6.6 9.4 4.4 6.3 1.2 3.0 3 0 0 3 3 3 0 TAP42-like family zf-C2H2_aberr PF17017.5 KFQ98228.1 - 8.6e-07 29.3 2.7 6.2e-05 23.2 0.2 2.2 1 1 1 2 2 2 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 KFQ98228.1 - 0.0017 19.1 6.3 0.54 11.3 2.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFQ98228.1 - 0.012 16.0 6.8 0.68 10.5 2.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 KFQ98228.1 - 0.16 11.6 0.1 0.75 9.5 0.0 2.0 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain ARS2 PF04959.13 KFQ98228.1 - 0.21 12.0 4.5 9.5 6.5 0.4 2.8 1 1 2 3 3 3 0 Arsenite-resistance protein 2 NAD_binding_2 PF03446.15 KFQ98229.1 - 1.4e-50 171.6 0.2 2e-50 171.1 0.2 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFQ98229.1 - 9.9e-34 116.2 0.0 1.5e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 KFQ98229.1 - 5.7e-10 38.8 0.0 9.3e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KFQ98229.1 - 1.6e-07 31.8 0.0 4.4e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KFQ98229.1 - 0.00027 20.9 0.0 0.00059 19.8 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PDH PF02153.17 KFQ98229.1 - 0.0038 16.3 0.1 0.0049 15.9 0.1 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase IlvN PF07991.12 KFQ98229.1 - 0.0066 16.0 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KFQ98229.1 - 0.0097 16.2 0.0 0.034 14.4 0.0 2.1 2 1 0 2 2 2 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KFQ98229.1 - 0.066 12.8 0.0 3.7 7.1 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Homeodomain PF00046.29 KFQ98230.1 - 3.3e-21 74.9 4.9 5.6e-21 74.1 4.9 1.4 1 0 0 1 1 1 1 Homeodomain Homeodomain PF00046.29 KFQ98231.1 - 1.9e-19 69.3 8.0 2.2e-19 69.0 8.0 1.1 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ98231.1 - 5.8e-05 22.9 2.5 8.4e-05 22.4 2.5 1.4 1 1 0 1 1 1 1 Homeobox KN domain DUF1510 PF07423.11 KFQ98231.1 - 0.036 14.2 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1510) CI-B14_5a PF07347.12 KFQ98231.1 - 0.037 13.9 0.8 0.042 13.7 0.2 1.4 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Homez PF11569.8 KFQ98231.1 - 0.096 12.2 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DUF3528 PF12045.8 KFQ98232.1 - 2.5e-64 216.2 0.9 3.9e-64 215.5 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3528) Homeodomain PF00046.29 KFQ98232.1 - 6.1e-20 70.8 7.7 9.9e-20 70.2 7.7 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ98232.1 - 0.051 13.5 0.8 0.093 12.7 0.8 1.4 1 0 0 1 1 1 0 Homeobox KN domain Homeodomain PF00046.29 KFQ98233.1 - 8.2e-22 76.8 8.5 1.3e-21 76.2 8.5 1.3 1 0 0 1 1 1 1 Homeodomain DUF2209 PF09974.9 KFQ98233.1 - 0.18 12.1 0.1 0.29 11.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Homeodomain PF00046.29 KFQ98234.1 - 1.7e-21 75.8 9.1 1.7e-21 75.8 9.1 1.7 2 0 0 2 2 2 1 Homeodomain Homeodomain PF00046.29 KFQ98235.1 - 6.8e-23 80.3 9.1 1e-22 79.7 9.1 1.3 1 0 0 1 1 1 1 Homeodomain DUF2209 PF09974.9 KFQ98235.1 - 0.045 14.1 0.1 0.062 13.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Terminase_5 PF06056.12 KFQ98235.1 - 0.047 13.6 0.3 0.26 11.2 0.1 2.0 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) Homeobox_KN PF05920.11 KFQ98235.1 - 0.12 12.4 0.7 0.12 12.4 0.7 1.9 2 0 0 2 2 2 0 Homeobox KN domain DUF4074 PF13293.6 KFQ98236.1 - 1.6e-36 124.4 9.2 1.6e-36 124.4 9.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4074) Homeodomain PF00046.29 KFQ98236.1 - 1.5e-21 76.0 5.2 3.1e-21 75.0 5.2 1.6 1 0 0 1 1 1 1 Homeodomain Homeodomain PF00046.29 KFQ98237.1 - 1.2e-22 79.5 7.4 1.6e-22 79.1 7.4 1.1 1 0 0 1 1 1 1 Homeodomain YcgR PF07317.12 KFQ98237.1 - 0.014 15.2 0.2 0.37 10.7 0.0 2.1 1 1 1 2 2 2 0 Flagellar regulator YcgR Homeobox_KN PF05920.11 KFQ98237.1 - 0.07 13.1 3.9 0.083 12.8 0.6 2.2 2 0 0 2 2 2 0 Homeobox KN domain PH PF00169.29 KFQ98238.1 - 2.7e-17 63.2 0.8 5.4e-17 62.2 0.8 1.5 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.28 KFQ98238.1 - 2.1e-11 43.2 0.3 6.5e-11 41.7 0.3 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFQ98238.1 - 2.7e-10 39.8 0.1 5.9e-10 38.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFQ98238.1 - 4.2e-10 39.3 0.1 9.4e-10 38.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 KFQ98238.1 - 1.3e-05 25.6 3.4 4.5e-05 23.8 3.4 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 KFQ98238.1 - 1.6e-05 25.3 0.4 4.4e-05 23.8 0.4 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KFQ98238.1 - 2.2e-05 24.5 0.1 4.4e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 KFQ98238.1 - 0.033 14.0 0.1 0.065 13.0 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain PX PF00787.24 KFQ98239.1 - 1.4e-24 86.3 2.9 1.8e-24 85.9 2.9 1.2 1 0 0 1 1 1 1 PX domain Chromo_shadow PF01393.19 KFQ98240.1 - 3.4e-33 113.5 0.1 1.4e-29 101.9 0.0 2.4 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 KFQ98240.1 - 1.4e-20 72.9 0.1 1.1e-16 60.5 0.1 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 KFQ98240.1 - 0.0092 16.1 0.1 0.053 13.7 0.1 2.1 2 0 0 2 2 2 1 Polycomb-like MTF2 factor 2 RRM_1 PF00076.22 KFQ98241.1 - 1.2e-32 111.5 0.0 4.8e-15 55.1 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFQ98241.1 - 8.2e-09 35.5 0.1 0.00068 19.7 0.0 2.6 2 2 0 2 2 2 2 RNA recognition motif OB_RNB PF08206.11 KFQ98241.1 - 0.033 13.9 0.5 1.2 8.9 0.1 2.7 2 0 0 2 2 2 0 Ribonuclease B OB domain FARP PF01581.16 KFQ98242.1 - 0.056 13.9 0.9 83 4.4 0.0 3.7 3 0 0 3 3 3 0 FMRFamide related peptide family ORF45 PF17620.2 KFQ98242.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function NPFF PF15085.6 KFQ98242.1 - 0.16 12.3 1.3 20 5.6 0.1 3.0 2 1 1 3 3 3 0 Neuropeptide FF Cytochrom_C PF00034.21 KFQ98243.1 - 7.5e-14 52.7 0.1 9.7e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KFQ98243.1 - 1.8e-06 28.2 2.6 8.9e-06 25.9 2.6 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KFQ98243.1 - 8.3e-05 22.3 3.1 0.00098 18.8 3.1 2.3 1 1 0 1 1 1 1 Cytochrome c-550 domain UPF0128 PF03673.13 KFQ98243.1 - 0.071 12.6 0.1 0.096 12.2 0.1 1.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0128) Oxysterol_BP PF01237.18 KFQ98244.1 - 1.1e-130 435.8 2.6 1.1e-130 435.8 2.6 2.0 2 1 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.6 KFQ98244.1 - 2.2e-11 43.9 0.1 5.3e-11 42.7 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFQ98244.1 - 8.4e-08 32.7 1.3 4.7e-07 30.3 1.3 2.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFQ98244.1 - 3.5 8.1 6.0 4e+02 1.5 6.0 3.0 1 1 0 1 1 1 0 Pleckstrin homology domain Gasdermin PF04598.12 KFQ98245.1 - 7.5e-90 300.6 1.4 1.1e-89 300.1 1.4 1.2 1 0 0 1 1 1 1 Gasdermin pore forming domain Gasdermin_C PF17708.1 KFQ98245.1 - 9.8e-47 159.3 10.7 9.8e-47 159.3 10.7 1.6 2 0 0 2 2 2 1 Gasdermin PUB domain Guanylate_kin PF00625.21 KFQ98246.1 - 3.8e-49 166.8 0.0 7.3e-49 165.9 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase L27 PF02828.16 KFQ98246.1 - 5e-29 99.8 1.0 4e-17 61.7 0.1 3.2 3 0 0 3 3 3 2 L27 domain SH3_2 PF07653.17 KFQ98246.1 - 1.2e-11 44.1 0.3 4e-11 42.4 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain PDZ PF00595.24 KFQ98246.1 - 8.9e-11 42.0 0.9 1.9e-10 40.9 0.9 1.6 1 0 0 1 1 1 1 PDZ domain SH3_1 PF00018.28 KFQ98246.1 - 4.2e-06 26.3 0.1 1.1e-05 24.9 0.1 1.8 1 0 0 1 1 1 1 SH3 domain PDZ_6 PF17820.1 KFQ98246.1 - 3.5e-05 23.6 0.1 8.5e-05 22.3 0.1 1.7 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.6 KFQ98246.1 - 5e-05 23.1 0.0 0.0001 22.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PDZ_2 PF13180.6 KFQ98246.1 - 0.00017 21.9 0.1 0.00043 20.5 0.1 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 KFQ98246.1 - 0.00066 19.6 0.1 0.013 15.4 0.1 2.8 2 1 0 2 2 2 1 Tricorn protease PDZ domain Hormone_3 PF00159.18 KFQ98248.1 - 5.3e-19 68.0 1.1 1e-18 67.1 1.1 1.5 1 0 0 1 1 1 1 Pancreatic hormone peptide TUDOR PF00567.24 KFQ98249.1 - 2.8e-17 62.9 0.3 7.8e-17 61.4 0.3 1.8 1 0 0 1 1 1 1 Tudor domain Pkinase PF00069.25 KFQ98249.1 - 2.4e-15 56.6 0.0 8e-15 54.9 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ98249.1 - 3.5e-11 42.9 0.0 6.9e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase SNase PF00565.17 KFQ98249.1 - 0.0016 18.9 0.1 0.0047 17.4 0.1 1.9 1 0 0 1 1 1 1 Staphylococcal nuclease homologue CathepsinC_exc PF08773.11 KFQ98249.1 - 0.03 14.6 0.5 0.2 11.9 0.0 2.6 2 0 0 2 2 2 0 Cathepsin C exclusion domain Sfi1_C PF10638.9 KFQ98249.1 - 0.053 14.3 2.2 0.3 11.9 0.2 2.7 1 1 1 2 2 2 0 Spindle body associated protein C-terminus PHM7_cyt PF14703.6 KFQ98249.1 - 0.16 12.2 0.1 0.16 12.2 0.1 2.8 3 1 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DivIC PF04977.15 KFQ98249.1 - 2 8.2 7.9 1.1 9.1 2.9 2.9 2 0 0 2 2 2 0 Septum formation initiator Med28 PF11594.8 KFQ98249.1 - 6.5 6.8 9.2 1.2 9.2 4.3 2.4 2 1 1 3 3 3 0 Mediator complex subunit 28 FAM221 PF14753.6 KFQ98250.1 - 2.4e-94 314.5 7.4 2.9e-94 314.2 7.4 1.1 1 0 0 1 1 1 1 Protein FAM221A/B DUF4525 PF15027.6 KFQ98251.1 - 5.4e-77 256.1 0.5 6.7e-77 255.8 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4525) DUF4407 PF14362.6 KFQ98251.1 - 0.0014 18.0 0.4 0.062 12.6 0.0 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) RRM_1 PF00076.22 KFQ98252.1 - 7.6e-20 70.5 0.0 1.1e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFQ98252.1 - 0.18 11.9 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Apt1 PF10351.9 KFQ98252.1 - 0.29 9.9 11.8 0.31 9.9 11.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 KFQ98252.1 - 1.2 7.9 5.3 1.4 7.6 5.3 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 KFQ98252.1 - 1.6 7.5 6.3 1.8 7.2 6.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 KH_1 PF00013.29 KFQ98253.1 - 9.1e-59 195.2 13.3 3.3e-15 55.7 0.1 5.0 5 0 0 5 5 5 4 KH domain RRM_1 PF00076.22 KFQ98253.1 - 2.9e-17 62.2 0.0 6.7e-09 35.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_2 PF07650.17 KFQ98253.1 - 5.8e-16 58.1 5.8 0.0034 17.2 0.1 4.6 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 KFQ98253.1 - 7.4e-15 54.6 0.5 0.0024 17.7 0.0 4.7 4 0 0 4 4 4 4 KH domain KH_5 PF13184.6 KFQ98253.1 - 6e-07 29.5 5.9 0.61 10.2 0.1 4.3 4 0 0 4 4 4 3 NusA-like KH domain MOEP19 PF16005.5 KFQ98253.1 - 1.3e-05 25.1 0.1 0.14 12.1 0.0 4.3 5 0 0 5 5 5 1 KH-like RNA-binding domain RRM_5 PF13893.6 KFQ98253.1 - 4.1e-05 23.2 0.0 0.023 14.3 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4041 PF13250.6 KFQ98253.1 - 0.26 11.2 1.2 0.52 10.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) RsfS PF02410.15 KFQ98254.1 - 7.3e-26 90.5 0.1 8.5e-26 90.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation PKD PF00801.20 KFQ98255.1 - 6e-12 45.2 1.9 5.6e-11 42.1 0.1 3.0 3 0 0 3 3 3 1 PKD domain Tape_meas_lam_C PF09718.10 KFQ98256.1 - 4.7 7.4 6.9 22 5.3 0.3 2.6 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Kelch_1 PF01344.25 KFQ98257.1 - 8.2e-46 153.4 13.7 9.9e-13 47.5 0.5 5.8 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 KFQ98257.1 - 3e-34 117.2 1.0 3.1e-33 114.0 0.1 2.7 3 0 0 3 3 3 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFQ98257.1 - 9.6e-29 98.7 7.0 4.8e-09 36.2 0.0 6.3 2 1 4 6 6 6 5 Kelch motif BTB PF00651.31 KFQ98257.1 - 1.2e-28 99.5 1.2 1.2e-28 99.5 1.2 1.8 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.6 KFQ98257.1 - 2.1e-22 78.8 0.1 1.4e-08 34.6 0.0 5.5 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KFQ98257.1 - 2.7e-21 74.7 6.2 3.4e-06 26.8 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KFQ98257.1 - 6.8e-11 42.2 4.8 0.00041 20.6 0.0 5.7 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KFQ98257.1 - 3.1e-09 36.6 3.3 0.12 12.4 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Glyoxal_oxid_N PF07250.11 KFQ98257.1 - 0.038 13.2 1.5 0.2 10.8 0.3 2.5 2 1 1 3 3 3 0 Glyoxal oxidase N-terminus UvrD-helicase PF00580.21 KFQ98257.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain ADPRTs_Tse2 PF18648.1 KFQ98257.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Tse2 ADP-ribosyltransferase toxins Hyccin PF09790.9 KFQ98258.1 - 2.6e-130 434.2 0.4 4.3e-130 433.5 0.4 1.4 1 0 0 1 1 1 1 Hyccin DUF4462 PF14692.6 KFQ98259.1 - 0.36 10.3 0.9 0.61 9.6 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) IL6 PF00489.17 KFQ98260.1 - 2.3e-42 144.7 2.3 2.7e-42 144.5 2.3 1.0 1 0 0 1 1 1 1 Interleukin-6/G-CSF/MGF family IL11 PF07400.11 KFQ98260.1 - 0.0012 18.5 0.2 0.0015 18.2 0.2 1.1 1 0 0 1 1 1 1 Interleukin 11 Bac_GDH PF05088.12 KFQ98260.1 - 0.023 12.2 0.4 0.022 12.3 0.4 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase GCSF PF16647.5 KFQ98260.1 - 0.099 12.5 0.0 0.11 12.4 0.0 1.3 1 1 0 1 1 1 0 Granulocyte colony-stimulating factor RasGEF PF00617.19 KFQ98262.1 - 9.4e-52 175.8 3.4 2.7e-51 174.3 2.5 2.2 2 0 0 2 2 2 1 RasGEF domain DEP PF00610.21 KFQ98262.1 - 1.9e-15 56.7 0.1 5e-15 55.3 0.1 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RasGEF_N PF00618.20 KFQ98262.1 - 3.8e-08 33.5 0.8 1.1e-07 32.0 0.8 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif RA PF00788.23 KFQ98262.1 - 0.00069 20.2 1.2 0.068 13.8 0.1 3.0 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain zf-4CXXC_R1 PF10497.9 KFQ98263.1 - 4.6e-37 126.2 9.1 7.7e-37 125.5 9.1 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-H2C2_2 PF13465.6 KFQ98264.1 - 1.1e-15 57.3 8.8 4.2e-09 36.4 2.5 4.4 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ98264.1 - 3.1e-13 49.4 30.9 3.5e-06 27.1 1.1 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ98264.1 - 1.1e-08 35.2 28.9 7e-05 23.3 2.8 3.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFQ98264.1 - 0.00015 21.6 16.8 0.0089 16.0 2.2 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ98264.1 - 0.0016 18.7 4.0 0.43 10.9 1.1 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KFQ98264.1 - 0.0065 16.7 6.6 0.01 16.1 4.1 2.2 2 1 0 2 2 2 1 C2H2-type zinc ribbon DUF971 PF06155.12 KFQ98264.1 - 0.094 13.4 1.8 3.9 8.2 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF971) zf-LYAR PF08790.11 KFQ98264.1 - 0.24 11.3 3.6 6.8 6.7 0.3 2.8 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf_C2H2_ZHX PF18387.1 KFQ98264.1 - 0.91 9.2 3.6 8.3 6.1 0.0 2.6 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_5 PF13909.6 KFQ98264.1 - 1.9 8.3 16.9 2.2 8.1 2.5 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-met PF12874.7 KFQ98264.1 - 2 8.9 6.2 7.7 7.1 1.2 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Zn_Tnp_IS1 PF03811.13 KFQ98264.1 - 3 7.7 9.0 2.4 7.9 2.2 2.5 2 0 0 2 2 2 0 InsA N-terminal domain PPV_E2_N PF00508.17 KFQ98265.1 - 0.16 11.3 0.0 0.16 11.3 0.0 1.0 1 0 0 1 1 1 0 E2 (early) protein, N terminal ABC_membrane PF00664.23 KFQ98266.1 - 2.2e-133 444.1 35.6 6.8e-73 245.7 16.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFQ98266.1 - 1.4e-74 249.1 0.6 2.7e-37 128.3 0.1 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFQ98266.1 - 4e-18 65.7 1.3 1.8e-07 30.8 0.0 3.8 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFQ98266.1 - 1.8e-10 41.5 1.8 0.00037 20.9 0.1 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KFQ98266.1 - 3.5e-10 40.3 0.8 0.00054 20.2 0.1 3.1 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 KFQ98266.1 - 8.2e-08 31.5 1.8 0.00092 18.1 0.1 2.7 2 0 0 2 2 2 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 KFQ98266.1 - 1.4e-07 31.6 0.3 0.019 14.8 0.0 2.8 2 1 0 2 2 2 2 RsgA GTPase Rad17 PF03215.15 KFQ98266.1 - 1.5e-06 28.3 1.4 0.059 13.3 0.1 2.8 2 2 0 2 2 2 2 Rad17 P-loop domain G-alpha PF00503.20 KFQ98266.1 - 1.4e-05 24.4 0.0 0.043 13.0 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit AAA PF00004.29 KFQ98266.1 - 5.6e-05 23.6 4.4 0.42 11.0 0.6 4.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KFQ98266.1 - 8e-05 22.0 2.5 0.03 13.6 0.0 3.5 4 0 0 4 4 4 1 Zeta toxin AAA_5 PF07728.14 KFQ98266.1 - 9.8e-05 22.4 0.2 0.76 9.8 0.0 3.8 3 1 1 4 4 4 2 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KFQ98266.1 - 0.0001 22.6 0.4 0.13 12.5 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KFQ98266.1 - 0.00013 21.8 0.1 0.26 10.9 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_7 PF12775.7 KFQ98266.1 - 0.00019 21.0 0.0 0.53 9.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_29 PF13555.6 KFQ98266.1 - 0.00025 20.7 1.7 0.67 9.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.6 KFQ98266.1 - 0.00055 20.1 3.6 2.2 8.6 0.2 4.2 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 KFQ98266.1 - 0.001 18.9 0.1 4.5 7.0 0.0 4.2 2 2 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system PRK PF00485.18 KFQ98266.1 - 0.004 16.9 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.6 KFQ98266.1 - 0.0051 16.5 6.3 1.1 8.9 0.4 3.6 3 2 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 KFQ98266.1 - 0.0063 16.9 0.0 4 7.9 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_18 PF13238.6 KFQ98266.1 - 0.0074 16.8 0.0 1.1 9.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KFQ98266.1 - 0.0078 15.8 0.1 2.7 7.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.17 KFQ98266.1 - 0.0089 16.1 0.7 2.2 8.3 0.0 3.2 3 0 0 3 3 3 1 Helicase HerA, central domain ATP-synt_ab PF00006.25 KFQ98266.1 - 0.01 15.5 0.1 6.2 6.4 0.0 2.8 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.13 KFQ98266.1 - 0.015 14.5 0.2 2.4 7.3 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF815) APS_kinase PF01583.20 KFQ98266.1 - 0.025 14.5 0.1 0.59 10.0 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_24 PF13479.6 KFQ98266.1 - 0.027 14.2 0.8 5.9 6.6 0.1 2.7 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 KFQ98266.1 - 0.043 14.0 0.0 10 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KFQ98266.1 - 0.043 13.9 0.1 8 6.5 0.0 3.5 3 1 1 4 4 4 0 AAA domain Viral_helicase1 PF01443.18 KFQ98266.1 - 0.043 13.5 0.0 11 5.6 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 KFQ98266.1 - 0.046 13.1 0.0 7.7 5.8 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KFQ98266.1 - 0.05 13.3 1.4 38 4.0 0.0 4.1 4 0 0 4 4 4 0 IstB-like ATP binding protein KdpD PF02702.17 KFQ98266.1 - 0.056 12.9 0.1 8.4 5.8 0.0 2.4 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain MMR_HSR1 PF01926.23 KFQ98266.1 - 0.06 13.4 0.2 16 5.6 0.0 3.4 3 0 0 3 3 3 0 50S ribosome-binding GTPase NB-ARC PF00931.22 KFQ98266.1 - 0.07 12.3 1.2 16 4.6 0.1 3.1 3 0 0 3 3 3 0 NB-ARC domain NACHT PF05729.12 KFQ98266.1 - 0.083 12.8 0.2 7.5 6.4 0.0 2.6 2 0 0 2 2 2 0 NACHT domain tRNA_lig_kinase PF08303.11 KFQ98266.1 - 0.12 12.4 0.0 24 5.0 0.0 2.6 2 0 0 2 2 2 0 tRNA ligase kinase domain DUF2852 PF11014.8 KFQ98266.1 - 0.14 12.3 0.8 7.2 6.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) YL1_C PF08265.11 KFQ98266.1 - 0.16 11.7 0.4 0.38 10.5 0.4 1.6 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain PduV-EutP PF10662.9 KFQ98266.1 - 0.19 11.5 0.7 12 5.7 0.0 3.2 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation RepB-RCR_reg PF10723.9 KFQ98266.1 - 0.2 11.7 0.2 16 5.5 0.0 2.5 2 0 0 2 2 2 0 Replication regulatory protein RepB DUF2057 PF09829.9 KFQ98266.1 - 0.82 9.8 2.9 14 5.8 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2057) Integrin_beta PF00362.18 KFQ98267.1 - 1.8e-97 325.9 0.0 2.8e-97 325.3 0.0 1.3 1 0 0 1 1 1 1 Integrin beta chain VWA domain EGF_2 PF07974.13 KFQ98267.1 - 9.9e-07 29.0 55.8 4.8e-05 23.6 13.9 5.3 5 0 0 5 5 5 3 EGF-like domain I-EGF_1 PF18372.1 KFQ98267.1 - 0.0077 16.3 40.3 0.068 13.3 8.6 4.4 3 0 0 3 3 3 2 Integrin beta epidermal growth factor like domain 1 EGF_Tenascin PF18720.1 KFQ98267.1 - 0.016 15.2 27.5 0.1 12.6 1.7 4.2 3 0 0 3 3 3 0 Tenascin EGF domain Sigma_reg_N PF13800.6 KFQ98267.1 - 0.11 12.8 0.5 0.24 11.7 0.5 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Death PF00531.22 KFQ98270.1 - 8.7e-06 25.8 0.7 0.18 12.0 0.0 3.1 2 1 0 2 2 2 2 Death domain ZU5 PF00791.20 KFQ98270.1 - 2.8e-05 24.4 0.1 6.3e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 ZU5 domain SH3_2 PF07653.17 KFQ98270.1 - 0.00076 19.1 0.1 0.0015 18.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SHE3 PF17078.5 KFQ98270.1 - 0.21 11.3 1.6 2.8 7.6 0.0 3.0 3 0 0 3 3 3 0 SWI5-dependent HO expression protein 3 ABC_membrane_3 PF13748.6 KFQ98271.1 - 0.066 12.4 0.5 0.12 11.6 0.5 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region RPA43_OB PF17875.1 KFQ98272.1 - 6.9e-07 29.9 13.2 0.0013 19.4 13.1 3.3 1 1 0 1 1 1 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 KFQ98272.1 - 0.0043 17.4 0.0 0.0086 16.4 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_polI_A34 PF08208.11 KFQ98272.1 - 3.7 7.6 22.9 6.1 6.9 22.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 HLH PF00010.26 KFQ98273.1 - 4.6e-17 61.7 0.6 4.6e-17 61.7 0.6 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain ATP-gua_Ptrans PF00217.19 KFQ98277.1 - 4e-81 271.5 0.0 5e-81 271.2 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 KFQ98277.1 - 2.8e-31 107.7 0.0 4.9e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Keratin PF02422.16 KFQ98279.1 - 1.7e-31 107.8 16.4 1.9e-31 107.6 16.4 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFQ98280.1 - 1.7e-31 107.8 16.4 1.9e-31 107.6 16.4 1.0 1 0 0 1 1 1 1 Keratin PDZ PF00595.24 KFQ98288.1 - 2.1e-154 502.3 66.5 8.4e-17 61.3 1.1 14.1 14 0 0 14 14 14 12 PDZ domain PDZ_6 PF17820.1 KFQ98288.1 - 8.6e-78 256.1 36.3 1.2e-07 31.5 0.5 12.1 12 0 0 12 12 12 11 PDZ domain PDZ_2 PF13180.6 KFQ98288.1 - 5.2e-47 158.1 38.0 3.2e-05 24.2 0.1 12.5 13 0 0 13 13 13 11 PDZ domain L27_2 PF09045.10 KFQ98288.1 - 3.9e-32 110.0 5.5 8.2e-32 108.9 5.5 1.6 1 0 0 1 1 1 1 L27_2 MPDZ_u10 PF16667.5 KFQ98288.1 - 1.5e-22 80.3 14.9 1.5e-22 80.3 14.9 4.1 4 0 0 4 4 4 1 Unstructured region 10 on multiple PDZ protein L27_1 PF09058.10 KFQ98288.1 - 0.0012 18.8 2.2 0.0016 18.4 1.0 1.9 2 0 0 2 2 2 1 L27_1 PDZ_1 PF12812.7 KFQ98288.1 - 0.0062 16.5 0.4 7.6 6.6 0.0 4.1 4 0 0 4 4 4 1 PDZ-like domain LURAP PF14854.6 KFQ98289.1 - 1.5e-39 134.6 1.8 1.9e-39 134.3 1.8 1.1 1 0 0 1 1 1 1 Leucine rich adaptor protein Tax PF02959.16 KFQ98289.1 - 0.17 11.3 0.0 0.22 11.0 0.0 1.1 1 0 0 1 1 1 0 HTLV Tax Tyrosinase PF00264.20 KFQ98290.1 - 1.3e-33 117.2 0.1 3.2e-33 115.9 0.0 1.6 2 0 0 2 2 2 1 Common central domain of tyrosinase Laminin_EGF PF00053.24 KFQ98290.1 - 0.99 9.6 13.5 3.1 8.0 10.5 2.9 2 1 0 2 2 2 0 Laminin EGF domain Chromosome_seg PF13889.6 KFQ98292.1 - 9.7e-19 67.3 0.4 2.2e-18 66.2 0.4 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis DUF4210 PF13915.6 KFQ98292.1 - 9.6e-14 51.7 0.0 1.9e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Band_7 PF01145.25 KFQ98293.1 - 2.6e-31 109.0 0.1 2.6e-31 109.0 0.1 2.0 1 1 1 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KFQ98293.1 - 1.3e-17 63.5 0.7 4.1e-17 62.0 0.7 1.9 1 0 0 1 1 1 1 C-terminal region of band_7 DUF4769 PF15992.5 KFQ98293.1 - 0.016 15.0 0.4 0.024 14.4 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) Band_7_1 PF13421.6 KFQ98293.1 - 0.078 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family EpoR_lig-bind PF09067.10 KFQ98297.1 - 2.8e-51 172.1 0.3 4.4e-26 91.1 0.0 2.6 2 0 0 2 2 2 2 Erythropoietin receptor, ligand binding fn3 PF00041.21 KFQ98297.1 - 1.4e-23 83.0 11.5 2.3e-06 27.8 0.2 5.1 4 0 0 4 4 4 4 Fibronectin type III domain IL6Ra-bind PF09240.10 KFQ98297.1 - 2.7e-21 75.8 2.6 1.1e-09 38.6 0.1 3.1 3 0 0 3 3 3 2 Interleukin-6 receptor alpha chain, binding Bgal_small_N PF02929.17 KFQ98297.1 - 0.031 13.9 0.5 3.5 7.2 0.1 2.7 2 0 0 2 2 2 0 Beta galactosidase small chain Y_Y_Y PF07495.13 KFQ98297.1 - 0.038 13.9 3.6 3.2 7.8 0.0 4.1 4 0 0 4 4 4 0 Y_Y_Y domain Tissue_fac PF01108.17 KFQ98297.1 - 0.11 12.3 8.4 3.1 7.7 0.2 4.3 4 0 0 4 4 4 0 Tissue factor Aminotran_3 PF00202.21 KFQ98298.1 - 7.9e-93 311.3 0.0 1.2e-92 310.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KFQ98298.1 - 0.0023 17.2 0.0 0.11 11.7 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II zf-C2H2_jaz PF12171.8 KFQ98299.1 - 1.8e-10 40.8 8.8 7e-10 38.9 1.1 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding DnaJ PF00226.31 KFQ98299.1 - 7.4e-09 35.6 0.1 3.3e-08 33.5 0.1 2.3 1 0 0 1 1 1 1 DnaJ domain zf-met PF12874.7 KFQ98299.1 - 2.2e-07 31.1 8.6 1.5e-06 28.4 1.2 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFQ98299.1 - 2.9e-07 30.7 2.4 0.02 15.2 0.2 3.2 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFQ98299.1 - 0.01 16.6 5.6 1.1 10.3 0.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger PARM PF17061.5 KFQ98299.1 - 0.74 9.9 8.7 1.2 9.2 8.7 1.2 1 0 0 1 1 1 0 PARM SCAMP PF04144.13 KFQ98301.1 - 2.8e-15 57.1 2.2 3.4e-15 56.8 2.2 1.1 1 0 0 1 1 1 1 SCAMP family UPF0242 PF06785.11 KFQ98301.1 - 0.025 14.7 0.6 0.03 14.4 0.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus fn3 PF00041.21 KFQ98302.1 - 6.8e-38 128.9 11.5 6.2e-15 55.3 0.1 4.3 4 0 0 4 4 4 3 Fibronectin type III domain Cys_box PF17869.1 KFQ98302.1 - 4.5e-27 94.0 11.1 4.5e-27 94.0 11.1 2.5 2 0 0 2 2 2 1 Anosmin cysteine rich domain WAP PF00095.21 KFQ98302.1 - 9.3e-10 38.7 15.4 9.3e-10 38.7 15.4 2.6 2 1 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Interfer-bind PF09294.10 KFQ98302.1 - 0.00029 21.1 1.8 0.0072 16.6 0.1 3.1 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III Pur_ac_phosph_N PF16656.5 KFQ98302.1 - 0.0033 17.9 6.6 0.48 11.0 0.7 4.2 4 0 0 4 4 4 1 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 KFQ98302.1 - 0.053 13.9 1.3 2.1 8.8 1.0 3.1 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) Patatin PF01734.22 KFQ98303.1 - 2.6e-16 60.4 1.1 6.7e-15 55.8 1.1 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase Sulfatase PF00884.23 KFQ98304.1 - 1e-92 310.8 0.0 1.3e-92 310.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KFQ98304.1 - 4.7e-44 150.1 1.1 1e-43 149.0 1.1 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 KFQ98304.1 - 5e-09 36.2 0.1 0.00027 20.7 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase HAD_2 PF13419.6 KFQ98305.1 - 2.2e-12 47.4 0.0 2.9e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFQ98305.1 - 5.4e-08 33.4 0.0 6.6e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NaeI PF09126.10 KFQ98305.1 - 0.05 12.8 0.0 0.068 12.4 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease NaeI Hydrolase_6 PF13344.6 KFQ98305.1 - 0.12 12.6 0.0 0.33 11.1 0.0 1.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase COesterase PF00135.28 KFQ98306.1 - 1.2e-198 661.2 0.0 1.5e-198 660.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFQ98306.1 - 3.5e-07 30.3 0.2 2.3e-06 27.6 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold SCF PF02404.15 KFQ98306.1 - 0.13 11.6 0.0 2.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Stem cell factor TMEM171 PF15471.6 KFQ98308.1 - 0.049 12.6 0.5 0.051 12.6 0.5 1.3 1 1 0 1 1 1 0 Transmembrane protein family 171 DUF2098 PF09871.9 KFQ98308.1 - 3.9 7.9 6.9 3.2 8.2 1.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) PDZ_5 PF17817.1 KFQ98326.1 - 3.5e-28 97.7 2.2 1.6e-27 95.6 2.2 2.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFQ98326.1 - 1.5e-13 50.9 1.7 3.1e-13 49.9 1.7 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFQ98326.1 - 1.2e-06 28.2 0.3 2.5e-06 27.2 0.3 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFQ98326.1 - 0.0013 19.0 0.2 0.0061 16.9 0.4 2.0 2 0 0 2 2 2 1 PDZ domain UPF0154 PF03672.13 KFQ98326.1 - 0.031 14.3 0.2 0.081 13.0 0.2 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Sarcoglycan_2 PF05510.13 KFQ98327.1 - 1.9e-127 425.2 0.0 2.2e-127 425.0 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon Cas1_AcylT PF07779.12 KFQ98328.1 - 3e-217 722.2 27.4 3.7e-217 721.9 27.4 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 KFQ98328.1 - 0.051 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p FeoB_associated PF12669.7 KFQ98328.1 - 0.2 12.1 0.8 35 4.9 0.1 4.2 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein Collagen PF01391.18 KFQ98329.1 - 7e-165 535.0 673.9 6.3e-10 38.7 33.6 20.9 2 1 18 20 20 20 20 Collagen triple helix repeat (20 copies) COLFI PF01410.18 KFQ98329.1 - 4.8e-107 356.6 0.1 5.9e-107 356.3 0.1 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Use1 PF09753.9 KFQ98330.1 - 0.00031 20.5 0.1 0.0004 20.2 0.1 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 Sec20 PF03908.13 KFQ98330.1 - 0.00043 20.1 0.2 0.00058 19.7 0.2 1.2 1 0 0 1 1 1 1 Sec20 Acyl-CoA_dh_1 PF00441.24 KFQ98331.1 - 2.1e-39 135.1 0.1 2.9e-39 134.7 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFQ98331.1 - 6.8e-23 80.7 0.0 1.3e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFQ98331.1 - 1.7e-12 47.8 0.0 2.8e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFQ98331.1 - 2.7e-10 40.9 0.0 6e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 KFQ98331.1 - 0.14 11.8 0.0 0.38 10.4 0.0 1.7 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF3011 PF11218.8 KFQ98331.1 - 0.15 12.0 0.1 0.24 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3011) G-gamma PF00631.22 KFQ98332.1 - 4.1e-11 42.7 0.0 4.3e-11 42.6 0.0 1.0 1 0 0 1 1 1 1 GGL domain 7tm_2 PF00002.24 KFQ98333.1 - 3.5e-79 265.6 17.2 4.5e-79 265.2 17.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFQ98333.1 - 6.2e-20 71.3 7.6 1.5e-19 70.1 7.6 1.7 1 0 0 1 1 1 1 Hormone receptor domain Vps54_N PF10475.9 KFQ98334.1 - 3e-113 377.9 13.0 8e-113 376.5 13.0 1.8 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KFQ98334.1 - 2.7e-96 321.9 3.0 2.7e-96 321.9 3.0 2.3 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) ERp29 PF07749.12 KFQ98334.1 - 0.71 10.8 3.2 3.2 8.7 0.1 3.4 3 0 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain Ig_3 PF13927.6 KFQ98335.1 - 5.9e-23 81.3 1.0 1.7e-12 47.7 0.4 3.4 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFQ98335.1 - 1e-17 64.0 0.1 2.6e-09 37.0 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 KFQ98335.1 - 9.5e-15 54.5 0.1 7.8e-07 29.2 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFQ98335.1 - 2.3e-14 53.4 0.6 2.2e-08 34.3 0.1 2.9 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 KFQ98335.1 - 1.7e-13 50.7 0.1 2.5e-06 27.6 0.0 4.2 3 2 1 4 4 4 2 Immunoglobulin V-set domain PKD_3 PF16820.5 KFQ98335.1 - 0.0014 18.3 0.0 0.0069 16.1 0.0 2.2 2 0 0 2 2 2 1 PKD-like domain Ig_6 PF18452.1 KFQ98335.1 - 0.0087 15.6 0.0 1 8.9 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.12 KFQ98335.1 - 0.031 14.4 0.0 3.5 7.7 0.0 2.4 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Pkinase PF00069.25 KFQ98336.1 - 6.8e-69 232.2 0.0 7.9e-69 231.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ98336.1 - 1.4e-35 122.8 0.0 2.7e-35 121.9 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFQ98336.1 - 8.4e-07 29.2 0.2 0.0013 18.7 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KFQ98336.1 - 1.9e-05 24.1 0.0 3.6e-05 23.2 0.0 1.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFQ98336.1 - 0.00016 20.7 0.0 0.00027 20.0 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFQ98336.1 - 0.0031 16.9 0.1 0.0063 15.9 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KFQ98336.1 - 0.023 14.3 0.0 0.06 12.9 0.0 1.6 1 1 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KFQ98336.1 - 0.13 11.9 0.0 0.76 9.4 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF1720 PF08226.11 KFQ98338.1 - 1.1 9.7 4.0 2.7 8.5 3.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) AAA PF00004.29 KFQ98339.1 - 8.8e-59 197.7 0.0 1.6e-42 145.1 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-2N PF09263.10 KFQ98339.1 - 2.3e-36 124.0 0.1 3e-35 120.4 0.0 2.6 2 0 0 2 2 2 1 Peroxisome biogenesis factor 1, N-terminal PEX-1N PF09262.11 KFQ98339.1 - 9.9e-26 90.0 0.1 2.4e-25 88.7 0.1 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KFQ98339.1 - 7.6e-15 54.4 1.0 2.3e-09 36.9 0.0 3.5 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 KFQ98339.1 - 2.1e-10 41.2 1.8 0.00085 19.7 0.0 3.4 2 1 1 3 3 3 2 AAA ATPase domain RNA_helicase PF00910.22 KFQ98339.1 - 7.6e-07 29.5 0.0 0.0064 16.9 0.0 3.1 3 0 0 3 3 2 2 RNA helicase AAA_2 PF07724.14 KFQ98339.1 - 8.3e-07 29.3 0.0 0.0013 18.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KFQ98339.1 - 1.7e-06 28.2 0.0 0.07 13.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 KFQ98339.1 - 2.1e-06 27.6 0.0 0.00065 19.5 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KFQ98339.1 - 3.7e-06 27.0 0.0 0.01 15.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KFQ98339.1 - 3.8e-06 27.0 0.2 0.12 12.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KFQ98339.1 - 3.9e-06 26.2 0.0 0.00033 19.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.12 KFQ98339.1 - 4.4e-06 26.7 7.1 0.021 14.8 1.4 5.0 4 1 0 4 4 4 1 NACHT domain AAA_18 PF13238.6 KFQ98339.1 - 1.1e-05 26.0 0.1 0.11 13.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.17 KFQ98339.1 - 1.4e-05 24.9 0.1 0.083 12.6 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.6 KFQ98339.1 - 3e-05 24.4 0.1 0.0086 16.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KFQ98339.1 - 3.7e-05 23.1 0.3 0.03 13.5 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain Sigma54_activat PF00158.26 KFQ98339.1 - 6.7e-05 22.7 0.0 0.12 12.1 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 KFQ98339.1 - 0.00016 21.8 0.0 0.12 12.5 0.0 2.9 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_29 PF13555.6 KFQ98339.1 - 0.00029 20.5 1.9 0.011 15.4 0.9 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 KFQ98339.1 - 0.00031 21.0 0.1 0.81 9.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 KFQ98339.1 - 0.00035 20.6 0.2 0.89 9.6 0.1 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KFQ98339.1 - 0.00064 20.0 2.1 1.6 9.0 0.1 3.5 2 2 1 3 3 3 2 AAA domain AAA_25 PF13481.6 KFQ98339.1 - 0.00085 18.9 3.0 1.6 8.3 0.0 4.0 4 0 0 4 4 4 1 AAA domain T2SSE PF00437.20 KFQ98339.1 - 0.0013 17.9 0.0 0.096 11.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 KFQ98339.1 - 0.0018 17.6 0.2 1 8.6 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin ABC_tran PF00005.27 KFQ98339.1 - 0.002 18.7 5.9 0.091 13.3 0.5 3.7 3 1 1 4 4 3 1 ABC transporter AAA_7 PF12775.7 KFQ98339.1 - 0.002 17.7 0.0 0.79 9.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 KFQ98339.1 - 0.0026 17.2 0.4 2 7.8 0.1 2.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KFQ98339.1 - 0.003 17.3 0.0 1.7 8.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 KFQ98339.1 - 0.0043 16.4 0.0 0.8 9.0 0.0 2.5 2 0 0 2 2 2 1 KaiC Bac_DnaA PF00308.18 KFQ98339.1 - 0.0075 16.1 0.0 0.28 11.0 0.0 2.8 3 0 0 3 3 3 1 Bacterial dnaA protein AAA_30 PF13604.6 KFQ98339.1 - 0.012 15.4 0.4 1.3 8.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KFQ98339.1 - 0.015 15.7 0.5 8.9 6.7 0.0 3.0 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KFQ98339.1 - 0.023 14.6 0.4 0.063 13.2 0.0 1.9 2 0 0 2 2 1 0 Adenylylsulphate kinase Molydop_binding PF01568.21 KFQ98339.1 - 0.027 14.5 0.0 0.17 11.9 0.0 2.3 3 0 0 3 3 1 0 Molydopterin dinucleotide binding domain CoaE PF01121.20 KFQ98339.1 - 0.03 14.0 0.0 0.081 12.6 0.0 1.7 1 0 0 1 1 1 0 Dephospho-CoA kinase NB-ARC PF00931.22 KFQ98339.1 - 0.038 13.2 0.1 3.4 6.8 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain DUF2138 PF09909.9 KFQ98339.1 - 0.093 11.0 0.1 0.14 10.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) Dynamin_N PF00350.23 KFQ98339.1 - 0.12 12.5 1.0 17 5.4 0.3 2.7 2 0 0 2 2 2 0 Dynamin family AAA_23 PF13476.6 KFQ98339.1 - 0.12 12.8 2.4 0.36 11.3 0.5 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KFQ98339.1 - 0.14 12.1 0.4 0.86 9.5 0.0 2.2 2 0 0 2 2 2 0 NTPase Hpr_kinase_C PF07475.12 KFQ98339.1 - 0.28 10.7 1.4 1.1 8.7 0.1 2.2 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain DUF87 PF01935.17 KFQ98339.1 - 6.2 6.8 5.8 0.55 10.3 0.1 2.2 3 0 0 3 3 1 0 Helicase HerA, central domain Aminotran_1_2 PF00155.21 KFQ98340.1 - 3.5e-61 207.4 0.0 4.1e-61 207.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KFQ98340.1 - 0.00045 19.6 0.0 0.00075 18.9 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase IBR PF01485.21 KFQ98342.1 - 4.5e-21 74.8 36.1 2.1e-13 50.3 1.2 4.2 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain Ank_5 PF13857.6 KFQ98342.1 - 8.1e-10 38.8 1.2 0.00019 21.7 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFQ98342.1 - 1.5e-09 38.3 0.4 7.8e-05 23.2 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFQ98342.1 - 3.6e-09 36.7 0.1 0.0033 17.8 0.0 3.2 3 0 0 3 3 2 2 Ankyrin repeat Ank_3 PF13606.6 KFQ98342.1 - 6.3e-07 29.2 0.3 0.013 15.9 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KFQ98342.1 - 7.8e-07 29.5 0.1 0.0078 16.8 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) zf-RING_UBOX PF13445.6 KFQ98342.1 - 4.4e-05 23.4 30.6 0.00012 22.0 6.4 4.2 3 1 0 3 3 3 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFQ98342.1 - 0.00057 19.7 4.9 0.00057 19.7 4.9 4.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ98342.1 - 0.0012 19.2 8.7 0.0012 19.2 8.7 4.0 3 1 0 3 3 3 2 Ring finger domain zf-C3HC4_4 PF15227.6 KFQ98342.1 - 0.0044 17.2 6.5 0.0044 17.2 6.5 4.1 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KFQ98342.1 - 0.0056 16.5 6.1 0.0056 16.5 6.1 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) UIM PF02809.20 KFQ98342.1 - 0.1 12.5 0.7 0.39 10.7 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin interaction motif NUDIX_5 PF16705.5 KFQ98343.1 - 6.8e-86 286.5 0.0 1.2e-85 285.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX, or N-terminal NPxY motif-rich, region of KRIT FERM_M PF00373.18 KFQ98343.1 - 1e-19 71.1 0.6 2.4e-19 69.9 0.1 2.0 2 0 0 2 2 2 1 FERM central domain Ank_2 PF12796.7 KFQ98343.1 - 3.9e-16 59.4 0.1 1.1e-06 29.1 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFQ98343.1 - 1.9e-14 53.5 0.2 1.1e-09 38.3 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFQ98343.1 - 1.7e-11 44.4 0.5 5.9e-07 29.9 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KFQ98343.1 - 3.8e-10 39.7 0.2 0.018 15.4 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KFQ98343.1 - 7.6e-08 32.0 0.2 0.048 14.2 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat p450 PF00067.22 KFQ98344.1 - 1.4e-77 261.5 0.0 1.6e-77 261.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Archease PF01951.16 KFQ98344.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Archease protein family (MTH1598/TM1083) Frizzled PF01534.17 KFQ98346.1 - 2.6e-140 467.1 17.9 3.1e-140 466.8 17.9 1.0 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region DHHC PF01529.20 KFQ98346.1 - 0.56 10.3 12.2 0.58 10.3 1.0 3.4 2 1 1 3 3 3 0 DHHC palmitoyltransferase Pkinase PF00069.25 KFQ98348.1 - 1.3e-67 227.9 0.0 1.7e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ98348.1 - 2.8e-32 112.0 0.0 3.9e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFQ98348.1 - 3.8e-05 22.8 0.0 0.00013 21.0 0.0 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFQ98348.1 - 0.0017 17.8 0.0 0.0039 16.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFQ98348.1 - 0.012 15.5 0.0 0.083 12.8 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 KFQ98348.1 - 0.072 12.7 0.0 5.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 EphA2_TM PF14575.6 KFQ98349.1 - 0.00029 21.6 0.1 0.00046 21.0 0.1 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain FAM163 PF15069.6 KFQ98349.1 - 0.0017 18.8 0.6 0.0027 18.2 0.6 1.3 1 0 0 1 1 1 1 FAM163 family Cadherin_C_2 PF16492.5 KFQ98349.1 - 0.0026 18.5 1.2 0.0051 17.5 1.2 1.5 1 1 0 1 1 1 1 Cadherin cytoplasmic C-terminal Comm PF15957.5 KFQ98349.1 - 0.016 15.6 0.0 0.026 14.9 0.0 1.3 1 0 0 1 1 1 0 Commissureless Prominin PF05478.11 KFQ98349.1 - 0.03 12.3 4.4 0.038 12.0 4.4 1.1 1 0 0 1 1 1 0 Prominin CD34_antigen PF06365.12 KFQ98349.1 - 0.04 13.5 1.3 0.04 13.5 1.3 1.7 1 1 1 2 2 2 0 CD34/Podocalyxin family MLANA PF14991.6 KFQ98349.1 - 0.056 13.7 0.1 0.078 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein melan-A DUF4500 PF14937.6 KFQ98349.1 - 0.062 13.3 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) TMIE PF16038.5 KFQ98349.1 - 0.063 13.1 3.0 0.1 12.5 3.0 1.4 1 0 0 1 1 1 0 TMIE protein LYRIC PF15686.5 KFQ98349.1 - 0.066 12.8 0.1 0.087 12.4 0.1 1.0 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Protocadherin PF08374.11 KFQ98349.1 - 0.14 12.1 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Protocadherin TMEM154 PF15102.6 KFQ98349.1 - 0.16 11.9 0.0 0.22 11.5 0.0 1.3 1 1 0 1 1 1 0 TMEM154 protein family U79_P34 PF03064.16 KFQ98349.1 - 0.33 10.3 4.6 0.43 9.9 4.6 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Synaptobrevin PF00957.21 KFQ98349.1 - 0.79 9.5 3.6 1.5 8.6 3.6 1.4 1 0 0 1 1 1 0 Synaptobrevin SKG6 PF08693.10 KFQ98349.1 - 1.7 8.1 7.8 2.9 7.4 7.8 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Claudin_2 PF13903.6 KFQ98350.1 - 0.014 15.2 13.4 0.1 12.4 13.3 2.2 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction MMR_HSR1 PF01926.23 KFQ98351.1 - 8.6e-23 80.6 0.0 1.7e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.22 KFQ98351.1 - 5.9e-18 64.9 4.3 4e-17 62.2 4.3 2.0 1 1 0 1 1 1 1 GTP1/OBG FeoB_N PF02421.18 KFQ98351.1 - 6.7e-12 45.2 0.1 1e-10 41.4 0.1 2.6 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KFQ98351.1 - 0.0001 21.9 0.0 0.0091 15.5 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KFQ98351.1 - 0.00019 20.5 0.1 0.14 11.1 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 KFQ98351.1 - 0.0013 18.2 0.0 0.0031 17.0 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1_Xtn PF16897.5 KFQ98351.1 - 0.055 13.5 0.1 0.24 11.4 0.1 1.9 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain ATP_bind_1 PF03029.17 KFQ98351.1 - 0.078 12.7 0.4 0.41 10.4 0.1 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.19 KFQ98351.1 - 0.12 11.9 0.2 5.6 6.5 0.2 2.2 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain UvrD-helicase PF00580.21 KFQ98351.1 - 0.16 11.4 2.5 0.14 11.6 0.6 1.7 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain DUF4574 PF15141.6 KFQ98351.1 - 0.18 11.7 2.2 0.58 10.1 2.2 1.8 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Dynamin_N PF00350.23 KFQ98351.1 - 1.6 8.8 4.0 11 6.1 0.1 2.8 2 1 1 3 3 3 0 Dynamin family F420_oxidored PF03807.17 KFQ98354.1 - 4.5e-18 65.6 0.0 8.9e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Ferric_reduct PF01794.19 KFQ98354.1 - 9.6e-16 58.0 9.0 2.1e-14 53.7 4.8 2.5 1 1 1 2 2 2 2 Ferric reductase like transmembrane component NAD_binding_2 PF03446.15 KFQ98354.1 - 4.7e-05 23.6 0.0 8.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KFQ98354.1 - 0.0039 16.6 0.0 0.0067 15.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KFQ98354.1 - 0.018 15.1 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF2768 PF10966.8 KFQ98354.1 - 0.045 14.2 3.0 0.19 12.2 3.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2768) IlvN PF07991.12 KFQ98354.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 KFQ98354.1 - 0.17 12.4 0.0 0.56 10.7 0.0 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding Ferric_reduct PF01794.19 KFQ98355.1 - 5.2e-13 49.2 17.4 3.2e-12 46.6 4.0 2.9 2 1 1 3 3 3 2 Ferric reductase like transmembrane component MgtE PF01769.16 KFQ98355.1 - 7.1 7.0 10.0 4.3 7.7 3.5 2.5 2 1 0 2 2 2 0 Divalent cation transporter zf-C2H2_jaz PF12171.8 KFQ98356.1 - 4.7e-06 26.7 10.5 4.7e-06 26.7 10.5 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Ferric_reduct PF01794.19 KFQ98359.1 - 4.4e-13 49.4 10.1 8.5e-13 48.5 6.1 2.4 1 1 1 2 2 2 1 Ferric reductase like transmembrane component F420_oxidored PF03807.17 KFQ98359.1 - 4.8e-12 46.3 0.1 8e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 KFQ98359.1 - 0.00011 21.9 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 KFQ98359.1 - 0.00033 20.8 0.0 0.00052 20.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KFQ98359.1 - 0.0015 17.9 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rossmann-like PF10727.9 KFQ98359.1 - 0.038 13.9 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain NAD_Gly3P_dh_N PF01210.23 KFQ98359.1 - 0.12 12.4 0.1 1 9.3 0.0 2.1 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus EF-hand_1 PF00036.32 KFQ98360.1 - 2.8e-17 60.9 1.5 0.00036 19.9 0.0 5.4 5 1 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 KFQ98360.1 - 3.2e-14 52.5 1.8 2.2e-10 40.2 0.0 3.6 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KFQ98360.1 - 8.3e-14 50.3 0.3 0.00018 21.1 0.0 4.6 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 KFQ98360.1 - 7.1e-13 48.8 0.2 0.00011 22.6 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KFQ98360.1 - 1.2e-11 43.6 1.8 0.00085 18.7 0.1 3.7 4 0 0 4 4 4 3 EF hand VbhA PF18495.1 KFQ98360.1 - 0.059 13.2 0.1 15 5.6 0.0 2.5 2 0 0 2 2 2 0 Antitoxin VbhA DUF2835 PF11197.8 KFQ98360.1 - 0.064 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2835) Reprolysin PF01421.19 KFQ98361.1 - 1e-60 205.1 0.0 1e-60 205.1 0.0 1.8 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.12 KFQ98361.1 - 7.7e-28 97.2 7.3 7.7e-28 97.2 7.3 3.9 3 2 0 3 3 3 1 ADAM cysteine-rich Pep_M12B_propep PF01562.19 KFQ98361.1 - 1.6e-15 57.5 1.8 1.6e-15 57.5 1.8 1.9 2 0 0 2 2 2 1 Reprolysin family propeptide Disintegrin PF00200.23 KFQ98361.1 - 3.2e-15 56.7 30.4 3.2e-15 56.7 30.4 4.0 4 1 0 4 4 4 1 Disintegrin Reprolysin_3 PF13582.6 KFQ98361.1 - 7.6e-08 32.9 0.0 1.5e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFQ98361.1 - 2.4e-06 27.9 0.0 6.4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 EGF_2 PF07974.13 KFQ98361.1 - 0.0012 19.1 10.8 0.0012 19.1 10.8 6.3 4 2 0 4 4 4 1 EGF-like domain ADAM_CR_2 PF17771.1 KFQ98361.1 - 0.061 13.8 0.4 0.061 13.8 0.4 6.0 4 1 2 6 6 6 0 ADAM cysteine-rich domain FRP PF18032.1 KFQ98361.1 - 0.2 12.3 0.2 0.41 11.3 0.2 1.4 1 0 0 1 1 1 0 Photoprotection regulator fluorescence recovery protein zf-DBF PF07535.12 KFQ98362.1 - 2.2e-17 62.9 2.9 5.9e-17 61.5 2.9 1.8 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.26 KFQ98362.1 - 0.0047 17.3 0.3 0.033 14.6 0.1 2.7 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DnaI_N PF07319.11 KFQ98362.1 - 9.7 6.9 7.1 4.6 8.0 0.8 3.5 4 0 0 4 4 4 0 Primosomal protein DnaI N-terminus RUN PF02759.19 KFQ98363.1 - 2.6e-25 88.9 0.1 7.4e-25 87.5 0.0 1.8 2 0 0 2 2 2 1 RUN domain DUF4477 PF14780.6 KFQ98363.1 - 0.022 14.4 0.4 0.11 12.1 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4477) ABC_tran PF00005.27 KFQ98364.1 - 7e-34 117.3 0.0 8e-34 117.1 0.0 1.0 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 KFQ98364.1 - 0.00016 21.9 0.0 0.00025 21.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFQ98364.1 - 0.00066 20.1 0.3 0.031 14.7 0.3 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 KFQ98364.1 - 0.00076 18.4 0.1 0.003 16.4 0.0 1.8 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_28 PF13521.6 KFQ98364.1 - 0.001 19.3 0.3 0.039 14.2 0.6 2.1 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.15 KFQ98364.1 - 0.0011 19.0 0.1 0.0018 18.2 0.1 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KFQ98364.1 - 0.0021 18.4 0.1 0.0031 17.9 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KFQ98364.1 - 0.0023 17.4 0.3 0.068 12.6 0.3 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain G-alpha PF00503.20 KFQ98364.1 - 0.0026 17.0 0.0 0.0027 16.9 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit SbcCD_C PF13558.6 KFQ98364.1 - 0.0065 16.7 0.3 0.17 12.1 0.3 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 KFQ98364.1 - 0.0068 16.2 0.0 0.012 15.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.25 KFQ98364.1 - 0.0084 15.8 0.1 0.39 10.4 0.1 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.14 KFQ98364.1 - 0.01 15.8 0.1 0.18 11.8 0.1 2.4 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 KFQ98364.1 - 0.019 14.7 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KFQ98364.1 - 0.024 14.5 0.1 0.057 13.3 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase DUF87 PF01935.17 KFQ98364.1 - 0.032 14.3 0.0 0.069 13.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_7 PF12775.7 KFQ98364.1 - 0.037 13.6 0.1 0.091 12.3 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_21 PF13304.6 KFQ98364.1 - 0.048 13.5 0.0 2.1 8.1 0.0 2.2 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFQ98364.1 - 0.053 13.3 0.0 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 KFQ98364.1 - 0.065 13.6 0.1 0.1 12.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain PRK PF00485.18 KFQ98364.1 - 0.068 12.9 0.8 0.26 11.0 0.8 1.9 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF815 PF05673.13 KFQ98364.1 - 0.097 11.8 0.0 0.23 10.6 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF815) TniB PF05621.11 KFQ98364.1 - 0.1 12.0 0.0 3 7.2 0.0 2.1 1 1 0 2 2 2 0 Bacterial TniB protein MIP PF00230.20 KFQ98366.1 - 2.1e-52 178.1 12.6 2.6e-52 177.8 12.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein Epimerase_2 PF02350.19 KFQ98374.1 - 2.8e-67 227.0 0.1 4.4e-67 226.4 0.1 1.2 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase ROK PF00480.20 KFQ98374.1 - 1.4e-56 192.1 2.3 2.6e-56 191.3 2.3 1.4 1 0 0 1 1 1 1 ROK family Hexokinase_1 PF00349.21 KFQ98374.1 - 0.00038 20.4 0.0 0.00076 19.4 0.0 1.4 1 0 0 1 1 1 1 Hexokinase DRTGG PF07085.12 KFQ98374.1 - 0.0016 18.2 0.2 0.0051 16.6 0.2 1.9 1 0 0 1 1 1 1 DRTGG domain BcrAD_BadFG PF01869.20 KFQ98374.1 - 0.0039 16.7 1.9 1.3 8.5 0.1 2.4 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family FGGY_N PF00370.21 KFQ98374.1 - 0.0073 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Glucokinase PF02685.16 KFQ98374.1 - 0.12 11.4 2.3 0.24 10.4 0.0 2.5 3 0 0 3 3 3 0 Glucokinase Clathrin_lg_ch PF01086.17 KFQ98375.1 - 9.7e-54 182.8 9.0 1.8e-53 181.9 9.0 1.5 1 1 0 1 1 1 1 Clathrin light chain CENP-Q PF13094.6 KFQ98375.1 - 5.6e-05 23.4 2.2 6.9e-05 23.1 2.2 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Myc-LZ PF02344.15 KFQ98375.1 - 0.0038 17.3 1.4 0.0088 16.1 1.4 1.6 1 0 0 1 1 1 1 Myc leucine zipper domain ORC3_N PF07034.11 KFQ98375.1 - 0.046 12.8 2.1 0.066 12.3 2.1 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus TBCA PF02970.16 KFQ98375.1 - 2.5 8.5 10.1 4 7.8 8.0 2.3 2 1 1 3 3 3 0 Tubulin binding cofactor A NeuB PF03102.14 KFQ98376.1 - 1.5e-78 263.6 0.0 1.7e-78 263.4 0.0 1.1 1 0 0 1 1 1 1 NeuB family SAF PF08666.12 KFQ98376.1 - 2.3e-06 28.1 0.2 4.5e-06 27.2 0.2 1.5 1 0 0 1 1 1 1 SAF domain ChapFlgA PF13144.6 KFQ98376.1 - 0.0072 16.4 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Chaperone for flagella basal body P-ring formation Opiods_neuropep PF01160.18 KFQ98376.1 - 0.6 10.2 0.0 0.6 10.2 0.0 2.9 3 0 0 3 3 3 0 Vertebrate endogenous opioids neuropeptide zf-RING_2 PF13639.6 KFQ98377.1 - 2.1e-12 47.2 9.9 2.1e-12 47.2 9.9 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KFQ98377.1 - 3.1e-08 33.8 8.8 3.1e-08 33.8 8.8 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KFQ98377.1 - 1e-07 31.6 6.0 1e-07 31.6 6.0 1.9 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFQ98377.1 - 1.2e-07 31.5 9.6 2.5e-07 30.4 9.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ98377.1 - 7.8e-07 28.9 9.2 1.5e-06 28.0 9.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFQ98377.1 - 1.9e-06 27.7 7.4 3.9e-06 26.7 7.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFQ98377.1 - 1.9e-05 24.4 7.4 1.9e-05 24.4 7.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFQ98377.1 - 0.0005 20.0 5.3 0.0015 18.5 5.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KFQ98377.1 - 0.0013 18.7 3.2 0.0013 18.7 3.2 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KFQ98377.1 - 0.011 15.6 8.4 0.011 15.6 8.4 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 KFQ98377.1 - 0.098 12.7 2.9 0.3 11.1 2.9 1.9 1 0 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 KFQ98377.1 - 0.099 12.3 7.4 0.21 11.2 7.4 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 KFQ98377.1 - 0.41 10.8 9.5 0.82 9.8 9.5 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KFQ98377.1 - 0.97 9.7 7.5 3.2 8.0 7.5 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KFQ98377.1 - 3.5 7.5 7.9 9.8 6.1 7.9 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KFQ98377.1 - 8.2 6.8 8.3 10 6.5 7.2 1.8 2 0 0 2 2 1 0 RING-like domain SH2 PF00017.24 KFQ98378.1 - 7.1e-18 64.5 0.1 1.1e-17 63.8 0.1 1.3 1 0 0 1 1 1 1 SH2 domain Ank_2 PF12796.7 KFQ98390.1 - 1.6e-47 160.0 8.0 3.1e-19 69.4 1.0 5.6 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ98390.1 - 1.7e-38 130.5 3.9 7.4e-11 42.4 0.1 6.9 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ98390.1 - 8.2e-36 118.0 8.2 0.00015 22.0 0.0 10.2 9 1 0 9 9 9 7 Ankyrin repeat Ank PF00023.30 KFQ98390.1 - 3.2e-35 119.0 13.6 1.6e-05 25.1 0.0 9.3 8 1 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.6 KFQ98390.1 - 1.7e-32 111.0 6.2 2.3e-08 34.2 0.1 7.0 4 1 3 7 7 7 5 Ankyrin repeats (many copies) TPR_12 PF13424.6 KFQ98390.1 - 3.8e-05 23.9 0.0 0.11 12.8 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ98390.1 - 0.046 13.9 0.6 0.81 10.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ98390.1 - 0.086 12.7 0.1 0.45 10.4 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat I-set PF07679.16 KFQ98404.1 - 6.2e-40 135.2 1.5 5.3e-16 58.5 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ98404.1 - 9.9e-40 135.0 3.1 5.5e-17 62.2 0.1 3.1 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFQ98404.1 - 9.9e-30 102.7 1.5 5.2e-13 49.1 0.1 3.2 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFQ98404.1 - 9.3e-26 89.8 0.8 4.1e-11 42.9 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFQ98404.1 - 2.5e-17 63.0 1.1 2.6e-05 24.3 0.0 5.1 3 2 2 5 5 5 4 Immunoglobulin V-set domain Ig_5 PF16681.5 KFQ98404.1 - 1.3e-10 41.5 0.1 0.032 14.6 0.0 3.6 3 1 0 3 3 3 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFQ98404.1 - 4.2e-08 33.1 0.5 0.0072 16.4 0.1 3.5 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 KFQ98404.1 - 4.6e-07 30.0 1.6 0.11 12.8 0.0 4.0 3 2 1 4 4 4 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFQ98404.1 - 3.7e-06 26.9 1.0 0.1 12.6 0.0 2.7 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFQ98404.1 - 7.1e-06 25.5 0.0 0.068 12.7 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin domain V-set_CD47 PF08204.11 KFQ98404.1 - 0.00017 21.6 0.7 0.29 11.1 0.2 3.2 2 1 1 3 3 3 2 CD47 immunoglobulin-like domain Adeno_E3_CR1 PF02440.15 KFQ98404.1 - 0.0016 18.1 3.6 4.3 7.2 0.2 4.0 3 1 0 3 3 3 2 Adenovirus E3 region protein CR1 Ig_C17orf99 PF17736.1 KFQ98404.1 - 0.0018 18.3 0.9 1 9.4 0.1 4.0 3 2 0 3 3 3 1 C17orf99 Ig domain C2-set PF05790.15 KFQ98404.1 - 0.059 13.6 0.1 19 5.5 0.0 3.7 4 0 0 4 4 4 0 Immunoglobulin C2-set domain Neuromodulin PF06614.11 KFQ98405.1 - 1.1e-68 230.9 67.8 1.1e-68 230.9 67.8 1.8 2 0 0 2 2 2 1 Neuromodulin Neuromodulin_N PF10580.9 KFQ98405.1 - 1.3e-15 56.9 5.6 5.7e-15 54.8 5.6 2.2 1 0 0 1 1 1 1 Gap junction protein N-terminal region IQ PF00612.27 KFQ98405.1 - 1.6e-06 27.4 0.4 2.7e-06 26.7 0.4 1.4 1 0 0 1 1 1 1 IQ calmodulin-binding motif BTB PF00651.31 KFQ98406.1 - 6.4e-24 84.3 0.1 1.9e-23 82.8 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2 PF00096.26 KFQ98406.1 - 3.1e-22 77.7 42.1 1e-06 28.8 1.9 6.2 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ98406.1 - 3.5e-20 71.5 42.7 1.9e-06 28.0 2.7 7.2 7 1 0 7 7 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ98406.1 - 1e-15 57.0 35.3 0.00021 21.8 1.5 6.1 5 0 0 5 5 5 5 C2H2-type zinc finger zf-met PF12874.7 KFQ98406.1 - 1.3e-06 28.6 34.2 0.0035 17.7 1.1 6.0 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KFQ98406.1 - 1.1e-05 25.2 6.4 0.43 10.5 0.0 4.4 4 0 0 4 4 4 3 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KFQ98406.1 - 4.5e-05 23.3 29.2 0.0024 17.8 0.6 5.6 5 0 0 5 5 5 3 C2H2-type zinc finger BolA PF01722.18 KFQ98406.1 - 0.0012 19.0 1.3 0.66 10.3 0.2 3.8 2 1 1 3 3 3 1 BolA-like protein zf-C2H2_2 PF12756.7 KFQ98406.1 - 0.0021 18.4 23.8 0.022 15.1 9.3 4.2 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KFQ98406.1 - 0.0047 16.7 18.3 0.79 9.5 2.0 4.9 5 0 0 5 5 5 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFQ98406.1 - 0.0069 16.7 21.4 0.1 12.9 0.7 4.7 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFQ98406.1 - 0.016 15.5 22.2 1.4 9.3 3.4 4.2 2 1 3 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_11 PF17123.5 KFQ98406.1 - 0.23 11.3 8.5 18 5.2 0.0 4.8 5 0 0 5 5 5 0 RING-like zinc finger DUF2225 PF09986.9 KFQ98406.1 - 2.3 7.9 13.0 1.4 8.6 0.2 3.9 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) Endonuclease_7 PF02945.15 KFQ98406.1 - 4.3 7.3 13.0 1.6 8.7 4.4 3.7 1 1 1 2 2 2 0 Recombination endonuclease VII HNH_5 PF14279.6 KFQ98406.1 - 7.2 6.6 13.5 2.3 8.1 0.2 4.0 4 1 0 4 4 4 0 HNH endonuclease 7tm_1 PF00001.21 KFQ98407.1 - 3.1e-75 252.9 20.0 7.4e-75 251.7 20.0 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ98407.1 - 4.3e-10 39.4 18.6 7.6e-08 32.0 16.0 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFQ98407.1 - 3.2e-05 23.7 15.9 3.2e-05 23.7 15.9 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx TGT PF01702.18 KFQ98408.1 - 9.7e-79 265.0 0.0 1.1e-78 264.9 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DHHC PF01529.20 KFQ98410.1 - 5.6e-31 107.4 8.7 5.6e-31 107.4 8.7 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase VASt PF16016.5 KFQ98411.1 - 9.3e-37 126.8 2.6 1.6e-36 126.0 2.6 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KFQ98411.1 - 3.4e-27 94.6 0.3 1.1e-26 92.9 0.2 2.0 2 0 0 2 2 2 1 GRAM domain TarH PF02203.15 KFQ98411.1 - 0.014 15.3 0.6 0.037 14.0 0.6 1.6 1 0 0 1 1 1 0 Tar ligand binding domain homologue V-set PF07686.17 KFQ98412.1 - 3e-17 62.7 0.0 4.1e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFQ98412.1 - 7.6e-10 39.3 0.0 1.3e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFQ98412.1 - 1.5e-08 34.7 0.0 3e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ98412.1 - 1.6e-08 34.5 0.0 3.3e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFQ98412.1 - 7.5e-08 32.6 0.0 1.8e-07 31.4 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain V-set_CD47 PF08204.11 KFQ98412.1 - 0.00032 20.7 0.0 0.00044 20.2 0.0 1.1 1 0 0 1 1 1 1 CD47 immunoglobulin-like domain DUF3872 PF12988.7 KFQ98412.1 - 0.047 13.5 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3872) Receptor_2B4 PF11465.8 KFQ98412.1 - 0.17 12.1 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 Phospholip_A2_1 PF00068.19 KFQ98413.1 - 2.6e-33 114.8 14.0 3.2e-33 114.5 14.0 1.1 1 0 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.10 KFQ98413.1 - 0.017 15.3 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus coat protein VP1 Claudin_2 PF13903.6 KFQ98414.1 - 1e-18 67.8 0.8 1.7e-18 67.1 0.8 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFQ98414.1 - 9.3e-09 35.4 6.9 5.1e-06 26.4 6.9 2.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family TMEM190 PF15431.6 KFQ98414.1 - 0.023 14.9 0.2 0.023 14.9 0.2 1.8 2 0 0 2 2 2 0 Transmembrane protein 190 Apo-VLDL-II PF05418.11 KFQ98415.1 - 9.1e-44 147.9 0.4 1.1e-43 147.7 0.4 1.1 1 0 0 1 1 1 1 Apovitellenin I (Apo-VLDL-II) LSR PF05624.14 KFQ98416.1 - 3.9e-22 78.0 36.3 6e-22 77.4 36.3 1.3 1 0 0 1 1 1 1 Lipolysis stimulated receptor (LSR) V-set PF07686.17 KFQ98416.1 - 2.7e-07 30.7 4.1 0.0011 19.1 0.0 3.6 2 1 1 3 3 3 3 Immunoglobulin V-set domain ig PF00047.25 KFQ98416.1 - 0.11 12.7 1.9 1.8 8.8 0.0 2.7 3 0 0 3 3 3 0 Immunoglobulin domain I-set PF07679.16 KFQ98416.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin I-set domain HalX PF08663.10 KFQ98417.1 - 0.59 10.5 13.0 0.07 13.5 1.8 3.3 3 0 0 3 3 3 0 HalX domain Vac_Fusion PF02346.16 KFQ98417.1 - 1.9 8.2 11.7 2.6 7.7 0.1 4.2 3 1 1 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 DUF3287 PF11690.8 KFQ98417.1 - 2.2 8.0 16.0 0.2 11.4 2.1 3.9 2 2 2 4 4 4 0 Protein of unknown function (DUF3287) DUF4140 PF13600.6 KFQ98417.1 - 7.8 7.0 16.3 0.82 10.1 1.4 3.4 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) KIND PF16474.5 KFQ98418.1 - 5.2e-43 147.2 0.4 3.3e-32 111.9 0.0 2.1 1 1 1 2 2 2 2 Kinase non-catalytic C-lobe domain DUF4477 PF14780.6 KFQ98419.1 - 1.8e-39 135.3 5.1 2.5e-39 134.9 5.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) TFIID-18kDa PF02269.16 KFQ98420.1 - 1.9e-38 130.3 0.4 2.2e-38 130.1 0.4 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit GTP_EFTU_D2 PF03144.25 KFQ98420.1 - 0.12 12.8 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFQ98421.1 - 7e-20 71.2 0.0 8.8e-20 70.9 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFQ98421.1 - 2.3e-07 30.6 0.0 1.5e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KFQ98421.1 - 5e-07 29.4 0.0 6.9e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFQ98421.1 - 4.9e-06 26.5 0.0 0.00054 19.9 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KFQ98421.1 - 0.00044 20.3 0.1 0.17 11.9 0.0 2.2 1 1 1 2 2 2 2 Dynamin family SRPRB PF09439.10 KFQ98421.1 - 0.00069 19.1 0.0 0.00093 18.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KFQ98421.1 - 0.012 15.9 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 KFQ98421.1 - 0.018 14.1 0.0 0.027 13.5 0.0 1.3 1 1 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_21 PF13304.6 KFQ98421.1 - 0.024 14.4 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 KFQ98421.1 - 0.056 13.7 0.0 0.12 12.7 0.0 1.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 KFQ98421.1 - 0.058 13.1 0.0 0.064 13.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.12 KFQ98421.1 - 0.059 12.7 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 KFQ98421.1 - 0.11 12.3 0.0 1.2 8.9 0.0 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 KFQ98421.1 - 0.14 11.9 0.0 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein V-set PF07686.17 KFQ98422.1 - 2e-07 31.2 0.4 3.2e-07 30.5 0.1 1.5 2 0 0 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.16 KFQ98422.1 - 6.5e-06 26.1 0.2 0.0082 16.2 0.0 2.3 1 1 1 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ98422.1 - 1e-05 26.0 1.5 0.015 15.9 0.2 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFQ98422.1 - 1.5e-05 25.1 3.9 0.017 15.3 0.4 2.7 1 1 1 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFQ98422.1 - 3.9e-05 23.6 0.2 0.00011 22.2 0.1 1.8 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 KFQ98422.1 - 0.0047 17.2 2.2 0.85 10.0 0.2 2.5 1 1 1 2 2 2 2 Immunoglobulin domain DUF4174 PF13778.6 KFQ98424.1 - 2e-106 351.0 0.1 2.9e-38 131.0 1.4 3.5 3 0 0 3 3 3 3 Domain of unknown function (DUF4174) Nuc_sug_transp PF04142.15 KFQ98425.1 - 9.6e-51 172.8 10.9 1.4e-50 172.3 10.9 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KFQ98425.1 - 1.7e-06 28.2 4.8 1.7e-06 28.2 4.8 3.3 3 1 0 3 3 3 1 EamA-like transporter family Autophagy_N PF03986.13 KFQ98426.1 - 9.7e-47 158.4 1.7 2e-46 157.3 1.7 1.6 1 1 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 KFQ98426.1 - 1.5e-20 73.5 4.1 3.2e-20 72.5 4.1 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 KFQ98426.1 - 5.5e-16 57.8 0.7 1e-15 56.9 0.7 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal F5_F8_type_C PF00754.25 KFQ98427.1 - 4.2e-54 182.1 4.9 2.5e-27 95.5 1.1 3.0 2 0 0 2 2 2 2 F5/8 type C domain Cu-oxidase_3 PF07732.15 KFQ98427.1 - 4.7e-30 104.1 0.9 1.1e-08 35.1 0.0 5.9 5 1 0 5 5 5 4 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFQ98427.1 - 2e-14 53.5 1.9 1.2e-06 28.4 0.1 5.7 5 0 0 5 5 5 3 Multicopper oxidase U6-snRNA_bdg PF10596.9 KFQ98427.1 - 0.019 15.0 0.1 0.13 12.3 0.0 2.4 2 0 0 2 2 2 0 U6-snRNA interacting domain of PrP8 Folate_carrier PF01770.18 KFQ98428.1 - 9.8e-161 535.1 25.1 1.2e-160 534.8 25.1 1.1 1 0 0 1 1 1 1 Reduced folate carrier MFS_1 PF07690.16 KFQ98428.1 - 9e-10 38.0 19.7 9e-10 38.0 19.7 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1378 PF07125.11 KFQ98428.1 - 0.026 14.7 0.3 0.07 13.3 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) DUF4207 PF13904.6 KFQ98429.1 - 0.0044 16.7 39.6 0.0044 16.7 39.6 3.6 2 2 2 4 4 4 3 Domain of unknown function (DUF4207) DASH_Hsk3 PF08227.11 KFQ98430.1 - 3.4e-10 40.1 0.2 1.1e-09 38.5 0.2 1.9 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Synaptonemal_3 PF15191.6 KFQ98430.1 - 0.1 12.4 3.3 0.76 9.6 0.7 3.2 1 1 1 3 3 3 0 Synaptonemal complex central element protein 3 CC2-LZ PF16516.5 KFQ98430.1 - 0.11 12.9 0.6 0.11 12.9 0.6 3.2 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator MbeD_MobD PF04899.12 KFQ98430.1 - 3.9 7.6 9.7 1.5 9.0 0.6 3.1 1 1 2 3 3 3 0 MbeD/MobD like PI3K_P85_iSH2 PF16454.5 KFQ98430.1 - 4.7 6.8 16.2 0.19 11.3 3.7 2.6 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain NDK PF00334.19 KFQ98431.1 - 8e-73 242.8 0.0 9.1e-41 139.0 0.0 2.1 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 KFQ98431.1 - 5.3e-06 26.2 0.6 3.1e-05 23.8 0.3 2.2 2 0 0 2 2 2 1 DUF1126 PH-like domain Na_K-ATPase PF00287.18 KFQ98432.1 - 1e-86 290.6 2.0 1.3e-86 290.4 2.0 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain DERM PF14704.6 KFQ98433.1 - 3.2e-31 108.8 3.2 3.9e-31 108.6 3.2 1.1 1 0 0 1 1 1 1 Dermatopontin IL8 PF00048.20 KFQ98434.1 - 2.3e-11 43.7 0.4 3.8e-11 43.0 0.4 1.3 1 1 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like T-box PF00907.22 KFQ98435.1 - 6e-73 245.0 0.0 7.7e-73 244.7 0.0 1.1 1 0 0 1 1 1 1 T-box Got1 PF04178.12 KFQ98436.1 - 3.1e-39 133.9 15.2 8e-37 126.1 9.5 1.9 1 1 1 2 2 2 2 Got1/Sft2-like family Bac_export_2 PF01312.19 KFQ98436.1 - 0.14 11.3 0.8 0.15 11.2 0.8 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family DUF4064 PF13273.6 KFQ98436.1 - 0.29 11.4 8.1 0.5 10.7 4.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF5423 PF17461.2 KFQ98436.1 - 1 8.2 5.2 0.92 8.3 4.0 1.5 1 1 1 2 2 2 0 Family of unknown function (DUF5423) DUF2244 PF10003.9 KFQ98436.1 - 3.5 7.3 11.2 0.31 10.7 3.4 2.0 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) PGG PF13962.6 KFQ98436.1 - 7.2 6.5 9.0 0.19 11.6 1.6 2.1 2 1 1 3 3 3 0 Domain of unknown function TIP41 PF04176.13 KFQ98437.1 - 5.4e-66 221.3 0.4 6.6e-66 221.0 0.4 1.1 1 0 0 1 1 1 1 TIP41-like family Gas_vesicle_C PF01304.17 KFQ98437.1 - 0.2 11.7 3.9 7.3 6.7 0.5 2.4 2 0 0 2 2 2 0 Gas vesicles protein GVPc repeated domain 7tm_1 PF00001.21 KFQ98438.1 - 3.3e-48 164.3 18.8 3.3e-48 164.3 18.8 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFQ98438.1 - 0.0014 18.3 21.7 0.0023 17.6 21.4 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.15 KFQ98438.1 - 1.7 8.6 11.4 0.23 11.4 2.3 2.3 2 0 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa SNF2_N PF00176.23 KFQ98439.1 - 1.2e-76 257.7 3.7 6.2e-76 255.4 0.3 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KFQ98439.1 - 3.2e-14 53.2 0.0 1e-13 51.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFQ98439.1 - 1.9e-07 31.2 0.0 6.8e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFQ98439.1 - 0.00015 21.6 0.0 0.00037 20.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Coprogen_oxidas PF01218.18 KFQ98440.1 - 1.4e-131 437.6 0.0 1.6e-131 437.4 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Glyco_transf_29 PF00777.18 KFQ98441.1 - 4.9e-66 222.9 0.0 6.2e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Collagen PF01391.18 KFQ98442.1 - 5.4e-64 211.8 293.3 3e-07 30.1 27.4 11.2 2 1 5 7 7 7 5 Collagen triple helix repeat (20 copies) C1q PF00386.21 KFQ98442.1 - 1.5e-36 125.4 0.2 1.8e-36 125.1 0.2 1.1 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 KFQ98442.1 - 0.02 14.8 0.0 0.03 14.2 0.0 1.1 1 0 0 1 1 1 0 BclA C-terminal domain F5_F8_type_C PF00754.25 KFQ98443.1 - 1.2e-25 90.1 0.5 1.2e-25 90.1 0.5 1.6 2 0 0 2 2 2 1 F5/8 type C domain CUB PF00431.20 KFQ98443.1 - 4.6e-24 84.9 0.0 7.9e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 CUB domain LCCL PF03815.19 KFQ98443.1 - 9.9e-14 51.2 0.1 2.7e-13 49.8 0.1 1.7 1 0 0 1 1 1 1 LCCL domain Syndecan PF01034.20 KFQ98443.1 - 0.0058 16.5 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Syndecan domain DUF4448 PF14610.6 KFQ98443.1 - 0.024 14.4 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) CDC50 PF03381.15 KFQ98444.1 - 3.7e-86 289.1 0.7 4.7e-86 288.8 0.7 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CMS1 PF14617.6 KFQ98445.1 - 3.5e-28 98.6 0.8 5.8e-28 97.9 0.8 1.3 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KFQ98445.1 - 2.1e-06 27.6 0.0 3.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Herpes_ori_bp PF02399.15 KFQ98445.1 - 0.0072 14.4 0.1 0.0073 14.4 0.1 1.0 1 0 0 1 1 1 1 Origin of replication binding protein CortBP2 PF09727.9 KFQ98446.1 - 8.5e-64 215.0 28.7 8.5e-64 215.0 28.7 7.3 2 2 4 6 6 6 3 Cortactin-binding protein-2 Occludin_ELL PF07303.13 KFQ98446.1 - 0.0014 19.4 10.1 0.0014 19.4 10.1 8.9 3 3 6 9 9 9 4 Occludin homology domain RabGAP-TBC PF00566.18 KFQ98447.1 - 2.9e-22 79.4 1.3 5.4e-22 78.5 1.3 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.20 KFQ98447.1 - 4.5e-08 33.6 0.0 1.3e-07 32.1 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain CN_hydrolase PF00795.22 KFQ98448.1 - 1.1e-66 224.9 0.0 1.2e-66 224.7 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TPR_1 PF00515.28 KFQ98449.1 - 4.2e-38 127.6 26.0 3.3e-09 36.2 0.8 10.1 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ98449.1 - 2.1e-32 108.6 26.9 1.5e-06 27.9 0.2 10.6 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ98449.1 - 3.6e-29 98.5 20.8 0.00016 21.6 0.0 10.0 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ98449.1 - 1.2e-27 95.3 15.8 1e-06 28.3 1.2 7.7 6 2 2 8 8 8 6 TPR repeat TPR_14 PF13428.6 KFQ98449.1 - 1.9e-21 74.9 7.8 0.0013 19.4 0.0 8.7 5 3 5 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ98449.1 - 2.9e-19 69.1 10.3 7.6e-06 26.1 0.1 7.0 3 2 4 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ98449.1 - 2.9e-17 61.7 20.1 0.0037 17.5 0.1 9.8 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFQ98449.1 - 1.7e-13 50.3 7.3 1.3 9.8 0.0 9.1 9 1 0 9 9 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFQ98449.1 - 2e-12 47.1 2.6 0.16 12.1 0.1 7.0 3 3 4 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ98449.1 - 7.2e-10 39.2 17.3 0.041 14.4 0.1 6.7 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ98449.1 - 1.3e-08 35.4 5.2 2.1 9.0 0.0 6.9 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ98449.1 - 4.4e-08 32.6 3.2 0.04 14.0 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF5569 PF17729.1 KFQ98449.1 - 2.9e-06 27.3 2.7 1.2e-05 25.3 0.2 2.6 2 1 1 3 3 3 1 Family of unknown function (DUF5569) MIT PF04212.18 KFQ98449.1 - 6e-05 23.0 12.1 0.12 12.5 1.7 5.6 4 1 0 4 4 4 2 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 KFQ98449.1 - 0.00048 19.9 16.1 4.8 7.2 0.0 6.8 6 1 1 7 7 6 1 Tetratricopeptide repeat NRBF2_MIT PF17169.4 KFQ98449.1 - 0.00073 19.7 0.7 0.0083 16.3 0.1 2.8 2 0 0 2 2 2 1 MIT domain of nuclear receptor-binding factor 2 SHNi-TPR PF10516.9 KFQ98449.1 - 0.0049 16.3 0.8 4.2 6.9 0.0 4.3 4 1 1 5 5 5 1 SHNi-TPR TPR_MalT PF17874.1 KFQ98449.1 - 0.0085 15.5 2.4 0.095 12.1 0.1 3.2 3 3 0 3 3 3 1 MalT-like TPR region PPR PF01535.20 KFQ98449.1 - 0.018 15.3 0.3 7.5 7.0 0.0 3.6 3 0 0 3 3 2 0 PPR repeat Hypoth_Ymh PF09509.10 KFQ98449.1 - 0.022 14.7 1.7 6 6.8 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (Hypoth_ymh) HrpB1_HrpK PF09613.10 KFQ98449.1 - 0.027 14.1 0.9 6.8 6.3 0.1 3.5 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) RPN7 PF10602.9 KFQ98449.1 - 0.034 13.8 0.4 0.034 13.8 0.4 4.0 3 2 1 4 4 4 0 26S proteasome subunit RPN7 Mad3_BUB1_I PF08311.12 KFQ98449.1 - 0.2 11.7 10.6 0.59 10.1 0.2 4.7 5 1 0 5 5 5 0 Mad3/BUB1 homology region 1 ANAPC3 PF12895.7 KFQ98449.1 - 2.7 8.3 24.3 6.8 7.0 0.2 5.8 4 3 2 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 LNP1 PF15419.6 KFQ98451.1 - 1.8e-69 233.5 23.3 2.1e-69 233.3 23.3 1.0 1 0 0 1 1 1 1 Leukemia NUP98 fusion partner 1 DUF716 PF04819.12 KFQ98452.1 - 3.8e-35 120.5 12.3 7.1e-35 119.6 12.3 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF716) PB1 PF00564.24 KFQ98453.1 - 1.4e-11 44.1 0.2 2.7e-11 43.3 0.2 1.5 1 0 0 1 1 1 1 PB1 domain fn3 PF00041.21 KFQ98454.1 - 1.6e-14 54.0 14.6 2.7e-10 40.5 1.1 4.3 4 1 0 4 4 4 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFQ98454.1 - 2.9e-08 34.2 5.5 0.0018 18.8 0.5 3.2 2 1 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFQ98454.1 - 0.00017 21.9 1.7 0.26 11.6 0.0 3.5 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 KFQ98454.1 - 0.085 13.2 0.8 2.9 8.3 0.0 3.0 2 1 1 3 3 3 0 Uncharacterised conserved protein (DUF2369) SEA PF01390.20 KFQ98455.1 - 4e-25 88.0 8.6 2.2e-16 59.9 0.5 3.2 3 0 0 3 3 3 2 SEA domain EGF PF00008.27 KFQ98455.1 - 0.00033 20.9 14.9 0.00035 20.8 4.0 2.4 2 0 0 2 2 2 2 EGF-like domain DUF4214 PF13946.6 KFQ98455.1 - 0.0089 16.1 0.0 0.025 14.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4214) Dam PF05869.11 KFQ98455.1 - 0.045 13.3 0.1 0.091 12.3 0.1 1.4 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) Arb2 PF09757.9 KFQ98456.1 - 7.3e-08 31.8 0.2 1e-07 31.4 0.2 1.3 1 1 0 1 1 1 1 Arb2 domain DUF676 PF05057.14 KFQ98456.1 - 0.053 13.0 0.2 4 6.9 0.0 2.2 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DIM1 PF02966.16 KFQ98457.1 - 4e-55 185.2 0.1 4.6e-55 185.0 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KFQ98457.1 - 7.7e-06 25.8 0.0 9.8e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin tRNA_m1G_MT PF01746.21 KFQ98458.1 - 2e-30 106.0 0.0 3.6e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase PCNP PF15473.6 KFQ98459.1 - 2.4e-68 229.8 12.5 2.7e-68 229.6 12.5 1.0 1 0 0 1 1 1 1 PEST, proteolytic signal-containing nuclear protein family SPATIAL PF15256.6 KFQ98459.1 - 0.058 13.7 1.0 0.095 13.0 0.1 1.5 1 1 1 2 2 2 0 SPATIAL zf-H2C2_2 PF13465.6 KFQ98460.1 - 3e-48 160.2 84.9 5.9e-08 32.8 0.2 13.9 14 0 0 14 14 14 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ98460.1 - 1.9e-41 138.3 94.9 0.00019 21.7 0.9 13.3 13 0 0 13 13 13 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ98460.1 - 1.9e-39 130.9 88.6 0.00075 20.1 1.4 13.5 13 0 0 13 13 13 12 C2H2-type zinc finger BTB PF00651.31 KFQ98460.1 - 5.1e-22 78.2 2.0 5.1e-22 78.2 2.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2_6 PF13912.6 KFQ98460.1 - 6.2e-16 58.0 93.0 0.0001 22.2 0.6 12.0 13 1 0 13 13 11 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ98460.1 - 3.1e-11 43.2 58.6 0.0022 18.3 0.6 12.6 12 1 0 12 12 11 4 Zinc-finger double-stranded RNA-binding Integrase_H2C2 PF17921.1 KFQ98460.1 - 2.3e-08 34.0 1.8 1.7e-07 31.3 1.8 2.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-Di19 PF05605.12 KFQ98460.1 - 1e-07 32.1 49.4 0.0011 19.2 0.7 8.1 4 2 4 8 8 8 5 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KFQ98460.1 - 4.3e-06 27.0 67.8 0.81 10.1 0.6 12.2 3 1 10 13 13 12 6 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFQ98460.1 - 0.0003 21.1 61.0 0.32 11.4 0.4 11.6 11 0 0 11 11 10 3 Zinc-finger of C2H2 type HNH_5 PF14279.6 KFQ98460.1 - 0.0053 16.6 1.3 0.0053 16.6 1.3 6.9 8 2 1 9 9 7 1 HNH endonuclease zf-C2H2_9 PF16293.5 KFQ98460.1 - 0.0079 16.0 15.5 11 6.0 0.1 7.8 6 2 1 7 7 7 0 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 KFQ98460.1 - 0.011 15.5 59.7 0.046 13.5 0.0 11.6 12 0 0 12 12 12 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFQ98460.1 - 0.025 14.5 0.5 0.025 14.5 0.5 9.9 11 0 0 11 11 9 0 zinc-finger of a C2HC-type Ta0938 PF11494.8 KFQ98460.1 - 0.048 13.9 16.5 0.87 9.9 0.7 5.3 3 3 2 6 6 6 0 Ta0938 SNRNP27 PF08648.12 KFQ98460.1 - 0.31 11.1 2.6 9.4 6.4 0.8 3.1 2 0 0 2 2 2 0 U4/U6.U5 small nuclear ribonucleoproteins zinc_ribbon_15 PF17032.5 KFQ98460.1 - 0.53 11.1 43.3 5.2 7.9 1.9 8.3 3 1 7 10 10 10 0 zinc-ribbon family zf-H2C2 PF09337.10 KFQ98460.1 - 1.7 8.9 6.7 1.4 9.2 0.3 3.9 3 0 0 3 3 3 0 H2C2 zinc finger zf-C2H2_8 PF15909.5 KFQ98460.1 - 2.1 8.7 34.1 0.14 12.4 4.4 5.7 2 1 1 4 4 4 0 C2H2-type zinc ribbon PhnA_Zn_Ribbon PF08274.12 KFQ98460.1 - 2.8 8.0 8.2 7.1 6.7 0.0 5.3 6 1 0 6 6 4 0 PhnA Zinc-Ribbon Ribosomal_L24e PF01246.20 KFQ98461.1 - 2.2e-15 56.6 0.5 2.2e-15 56.6 0.5 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e LRR_9 PF14580.6 KFQ98462.1 - 2.7e-21 75.9 1.3 2.1e-16 59.9 0.1 2.6 2 1 1 3 3 3 2 Leucine-rich repeat LRR_4 PF12799.7 KFQ98462.1 - 1.5e-15 57.0 27.5 3.1e-05 24.2 3.9 4.9 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFQ98462.1 - 7.1e-13 48.1 28.0 2.9e-06 26.9 3.5 4.0 1 1 2 4 4 4 4 Leucine rich repeat IQ PF00612.27 KFQ98462.1 - 0.0015 18.2 0.1 0.0031 17.1 0.1 1.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif LRR_6 PF13516.6 KFQ98462.1 - 0.0034 17.3 13.8 0.3 11.3 0.5 5.7 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 KFQ98462.1 - 0.11 13.1 12.8 2.5 9.0 0.2 6.0 4 1 1 5 5 5 0 Leucine Rich Repeat Neurexophilin PF06312.12 KFQ98463.1 - 2.5e-48 164.3 0.0 4.1e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 Neurexophilin Filamin PF00630.19 KFQ98463.1 - 0.00026 21.8 0.0 0.00052 20.8 0.0 1.4 1 0 0 1 1 1 1 Filamin/ABP280 repeat CD20 PF04103.15 KFQ98463.1 - 0.091 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 CD20-like family Ank_2 PF12796.7 KFQ98464.1 - 1e-24 86.9 8.9 2.8e-12 47.1 0.2 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ98464.1 - 9.4e-23 80.3 3.1 0.00015 22.3 0.0 5.9 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KFQ98464.1 - 1.6e-21 75.7 8.5 0.00031 21.1 0.1 6.9 6 2 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 KFQ98464.1 - 3.7e-18 63.7 3.6 0.069 13.7 0.1 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KFQ98464.1 - 1.7e-11 44.1 8.0 0.007 16.7 0.3 5.8 3 2 2 5 5 5 4 Ankyrin repeats (many copies) PD-C2-AF1 PF09310.10 KFQ98464.1 - 0.0025 17.3 0.0 0.014 14.8 0.0 2.0 2 0 0 2 2 2 1 POU domain, class 2, associating factor 1 Zona_pellucida PF00100.23 KFQ98465.1 - 4.9e-44 151.0 2.3 6.5e-44 150.6 2.3 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Ig_3 PF13927.6 KFQ98466.1 - 3.4e-30 104.5 14.0 6.4e-08 33.1 0.0 6.5 5 2 1 6 6 6 6 Immunoglobulin domain Ig_2 PF13895.6 KFQ98466.1 - 3.4e-25 88.2 9.4 7.9e-07 29.3 0.1 5.2 6 0 0 6 6 6 4 Immunoglobulin domain C2-set_2 PF08205.12 KFQ98466.1 - 1e-24 86.4 3.4 5.9e-19 67.9 0.0 4.5 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain ig PF00047.25 KFQ98466.1 - 4.6e-16 58.8 14.8 0.0014 18.8 0.6 7.4 5 3 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 KFQ98466.1 - 8.5e-16 57.8 15.4 0.0014 18.6 0.2 7.5 5 2 0 6 6 6 5 Immunoglobulin I-set domain V-set PF07686.17 KFQ98466.1 - 8.2e-10 38.8 12.3 0.0019 18.3 0.0 7.3 5 4 2 7 7 7 2 Immunoglobulin V-set domain C1-set PF07654.15 KFQ98466.1 - 6.8e-08 32.8 9.7 0.00014 22.2 0.1 4.8 5 1 1 6 6 6 2 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFQ98466.1 - 0.00044 19.8 0.0 0.14 11.8 0.0 3.2 3 0 0 3 3 3 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFQ98466.1 - 0.0078 16.2 0.3 1.4 9.0 0.0 3.5 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain Podoplanin PF05808.11 KFQ98466.1 - 0.061 13.4 0.6 0.14 12.2 0.6 1.7 1 0 0 1 1 1 0 Podoplanin PepSY_TM PF03929.16 KFQ98466.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 PepSY-associated TM region Cbl_N PF02262.16 KFQ98467.1 - 3e-47 159.7 1.7 5.5e-47 158.9 1.7 1.5 1 0 0 1 1 1 1 CBL proto-oncogene N-terminal domain 1 Cbl_N3 PF02762.14 KFQ98467.1 - 4.8e-45 151.3 0.0 8.3e-45 150.5 0.0 1.4 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain Cbl_N2 PF02761.14 KFQ98467.1 - 4e-40 136.4 1.4 7.8e-40 135.5 1.4 1.5 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain Prok-RING_4 PF14447.6 KFQ98467.1 - 2.4e-13 49.7 9.0 5.2e-13 48.6 9.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFQ98467.1 - 4.8e-11 42.3 8.0 1.1e-10 41.2 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ98467.1 - 1.4e-08 34.4 7.4 1.4e-08 34.4 7.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ98467.1 - 2.8e-08 33.9 7.5 2.8e-08 33.9 7.5 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFQ98467.1 - 6.4e-05 22.7 8.0 6.4e-05 22.7 8.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFQ98467.1 - 0.00068 19.6 5.2 0.00068 19.6 5.2 2.4 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFQ98467.1 - 0.0032 17.4 10.3 0.0089 16.0 10.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFQ98467.1 - 0.016 15.4 8.0 0.05 13.8 8.0 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KFQ98467.1 - 0.019 15.3 7.2 0.047 14.0 7.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 KFQ98467.1 - 0.73 9.5 7.7 1.8 8.3 7.7 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-UDP PF14569.6 KFQ98467.1 - 0.93 9.7 6.1 2.7 8.2 6.1 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger DUF2028 PF09667.10 KFQ98469.1 - 7e-62 208.9 11.1 7e-62 208.9 11.1 2.9 2 1 1 3 3 3 2 Domain of unknown function (DUF2028) HMG_box PF00505.19 KFQ98469.1 - 9.7e-17 61.2 0.8 9.7e-17 61.2 0.8 2.5 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFQ98469.1 - 1.7e-10 41.3 1.0 1.7e-10 41.3 1.0 2.3 2 0 0 2 2 2 1 HMG-box domain PorA PF11271.8 KFQ98469.1 - 0.57 9.4 3.2 0.24 10.7 0.6 1.6 2 0 0 2 2 2 0 Porin PorA CD47 PF04549.14 KFQ98470.1 - 5.8e-45 153.1 22.6 7.7e-45 152.7 22.6 1.2 1 0 0 1 1 1 1 CD47 transmembrane region V-set_CD47 PF08204.11 KFQ98470.1 - 1.8e-36 125.0 0.1 2.6e-36 124.5 0.1 1.2 1 0 0 1 1 1 1 CD47 immunoglobulin-like domain V-set PF07686.17 KFQ98470.1 - 1.4e-05 25.2 0.0 2.2e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFQ98470.1 - 0.0013 18.8 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFQ98470.1 - 0.0016 18.6 0.0 0.0032 17.6 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFQ98470.1 - 0.0037 17.8 0.0 0.0068 17.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain PigN PF04987.14 KFQ98470.1 - 0.0075 15.2 7.0 0.01 14.7 7.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Ig_2 PF13895.6 KFQ98470.1 - 0.011 16.0 0.1 0.055 13.8 0.1 1.9 1 1 0 1 1 1 0 Immunoglobulin domain MaAIMP_sms PF16951.5 KFQ98470.1 - 0.044 13.5 1.4 0.044 13.5 1.4 2.0 2 0 0 2 2 2 0 Putative methionine and alanine importer, small subunit IFT57 PF10498.9 KFQ98471.1 - 5.6e-138 459.8 8.3 6.4e-138 459.6 8.3 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Lipoprotein_20 PF13942.6 KFQ98471.1 - 0.0075 16.2 4.7 0.029 14.3 1.1 2.5 1 1 1 2 2 2 1 YfhG lipoprotein MCPsignal PF00015.21 KFQ98471.1 - 0.025 14.4 2.0 0.053 13.3 1.7 1.7 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Ribonuc_L-PSP PF01042.21 KFQ98471.1 - 0.059 13.4 0.6 0.25 11.4 0.1 2.2 2 0 0 2 2 2 0 Endoribonuclease L-PSP HAD_2 PF13419.6 KFQ98471.1 - 2.2 8.3 11.1 0.039 14.0 2.5 2.1 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF4407 PF14362.6 KFQ98471.1 - 3.7 6.8 10.6 0.58 9.5 5.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Med9 PF07544.13 KFQ98471.1 - 4.2 7.5 7.8 0.55 10.4 2.1 2.5 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF1664 PF07889.12 KFQ98471.1 - 9.2 6.3 8.8 4 7.5 1.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) V-set PF07686.17 KFQ98472.1 - 5.1e-25 87.8 6.7 6.8e-12 45.5 0.6 2.8 3 0 0 3 3 3 2 Immunoglobulin V-set domain I-set PF07679.16 KFQ98472.1 - 1.3e-16 60.5 0.1 9.9e-06 25.5 0.0 3.2 2 1 1 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 KFQ98472.1 - 4.2e-15 55.7 4.8 7.2e-07 29.3 0.4 3.3 3 0 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.6 KFQ98472.1 - 4.7e-15 56.0 4.5 2.8e-05 24.6 0.1 3.5 3 1 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFQ98472.1 - 4.7e-08 33.3 11.7 0.0068 16.7 1.0 3.9 1 1 2 3 3 3 2 Immunoglobulin domain V-set_CD47 PF08204.11 KFQ98472.1 - 1.3e-06 28.5 1.9 0.0077 16.2 0.0 2.3 2 0 0 2 2 2 2 CD47 immunoglobulin-like domain Izumo-Ig PF16706.5 KFQ98472.1 - 9e-05 22.5 0.1 0.057 13.5 0.0 2.4 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFQ98472.1 - 0.0006 20.2 0.5 0.52 10.8 0.1 3.7 3 1 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFQ98472.1 - 0.00088 19.5 0.1 1.1 9.6 0.0 4.0 4 0 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFQ98472.1 - 0.0014 18.2 0.1 0.63 9.6 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 KFQ98472.1 - 0.026 14.6 0.0 0.072 13.2 0.0 1.9 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Myosin_head PF00063.21 KFQ98473.1 - 1.4e-288 958.8 0.1 1.4e-288 958.8 0.1 2.9 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KFQ98473.1 - 4.3e-163 544.7 267.6 5.2e-163 544.5 267.6 1.0 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 KFQ98473.1 - 1.4e-17 63.2 6.1 4.1e-17 61.7 6.1 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Filament PF00038.21 KFQ98473.1 - 0.0021 17.7 48.4 0.0021 17.7 48.4 8.3 1 1 8 9 9 9 4 Intermediate filament protein AAA_22 PF13401.6 KFQ98473.1 - 0.07 13.4 0.0 0.07 13.4 0.0 6.0 4 2 2 6 6 6 0 AAA domain DUF1664 PF07889.12 KFQ98473.1 - 0.13 12.3 149.1 0.049 13.7 7.8 13.9 2 2 11 15 15 15 0 Protein of unknown function (DUF1664) IQ PF00612.27 KFQ98473.1 - 0.14 12.0 3.5 4.2 7.4 0.6 2.9 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_16 PF13191.6 KFQ98473.1 - 0.24 11.7 0.0 0.24 11.7 0.0 5.7 3 2 0 4 4 4 0 AAA ATPase domain ATG16 PF08614.11 KFQ98474.1 - 4.5e-05 23.8 28.0 4.5e-05 23.8 28.0 2.5 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) GAS PF13851.6 KFQ98474.1 - 0.55 9.5 61.8 0.24 10.7 31.5 3.9 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding DASH_Dam1 PF08653.10 KFQ98474.1 - 0.56 10.1 4.3 0.3 10.9 0.6 2.6 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF3584 PF12128.8 KFQ98474.1 - 2.6 5.4 47.5 3.9 4.8 47.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SH2 PF00017.24 KFQ98475.1 - 3.6e-15 55.8 0.2 5.1e-15 55.3 0.2 1.2 1 0 0 1 1 1 1 SH2 domain QVR PF17064.5 KFQ98475.1 - 0.07 13.4 0.3 0.11 12.7 0.3 1.2 1 0 0 1 1 1 0 Sleepless protein SIT PF15330.6 KFQ98477.1 - 1.6e-27 96.2 1.0 2.8e-27 95.4 1.0 1.4 1 0 0 1 1 1 1 SHP2-interacting transmembrane adaptor protein, SIT EF-hand_1 PF00036.32 KFQ98478.1 - 3.8e-07 29.2 0.8 1.4e-06 27.4 0.4 2.1 1 1 1 2 2 2 1 EF hand EF-hand_5 PF13202.6 KFQ98478.1 - 1.4e-06 27.5 1.0 6.2e-06 25.5 0.2 2.2 1 1 1 2 2 2 1 EF hand EF-hand_8 PF13833.6 KFQ98478.1 - 7.8e-06 25.6 0.1 1.1e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFQ98478.1 - 2.1e-05 24.1 0.5 4.1e-05 23.2 0.4 1.8 1 1 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KFQ98478.1 - 4.1e-05 23.9 0.6 0.00012 22.5 0.1 1.8 1 1 1 2 2 2 1 EF-hand domain pair DUF3736 PF12540.8 KFQ98479.1 - 0.15 12.2 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3736) Ig_3 PF13927.6 KFQ98480.1 - 5.3e-11 43.0 1.1 1.7e-07 31.7 0.1 2.6 2 1 1 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KFQ98480.1 - 1.3e-10 41.4 0.1 0.00013 22.2 0.1 2.3 2 1 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFQ98480.1 - 1.1e-09 38.2 0.9 8.6e-09 35.4 0.1 2.5 2 2 0 2 2 2 1 CD80-like C2-set immunoglobulin domain ig PF00047.25 KFQ98480.1 - 3e-08 33.7 0.1 3.4e-05 23.9 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFQ98480.1 - 0.00029 20.8 0.1 0.036 14.1 0.1 2.7 2 1 0 2 2 2 1 Immunoglobulin I-set domain Ig_6 PF18452.1 KFQ98480.1 - 0.0069 15.9 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFQ98481.1 - 2.5e-07 30.8 0.0 0.0011 19.1 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin V-set domain I-set PF07679.16 KFQ98481.1 - 0.074 13.1 0.0 0.44 10.6 0.0 2.1 3 0 0 3 3 3 0 Immunoglobulin I-set domain PH PF00169.29 KFQ98483.1 - 1.3e-13 51.3 0.2 3.8e-13 49.9 0.2 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFQ98483.1 - 0.0011 19.2 0.1 0.0029 17.8 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFQ98483.1 - 0.0014 19.0 0.6 0.0065 16.9 0.6 2.3 1 0 0 1 1 1 1 Pleckstrin homology domain Abhydrolase_1 PF00561.20 KFQ98484.1 - 1.9e-11 44.1 0.1 2.6e-10 40.4 0.1 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFQ98484.1 - 1e-09 38.0 0.0 4.9e-07 29.2 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFQ98484.1 - 2.7e-08 34.7 0.0 3.8e-08 34.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KFQ98484.1 - 7.5e-08 32.1 0.0 9.8e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2920 PF11144.8 KFQ98484.1 - 0.0017 17.6 0.0 0.0057 15.9 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2920) UPF0227 PF05728.12 KFQ98484.1 - 0.01 15.8 0.0 0.056 13.4 0.0 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0227) Ser_hydrolase PF06821.13 KFQ98484.1 - 0.011 15.6 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase BAAT_C PF08840.11 KFQ98484.1 - 0.03 14.2 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal B5 PF03484.15 KFQ98484.1 - 0.044 14.1 0.0 2.4 8.5 0.0 2.8 2 1 0 2 2 2 0 tRNA synthetase B5 domain CH PF00307.31 KFQ98485.1 - 1.2e-21 77.0 0.0 1.6e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 KFQ98485.1 - 2.4e-14 52.6 6.4 2.4e-14 52.6 6.4 1.8 2 0 0 2 2 2 1 Calponin family repeat Trypsin PF00089.26 KFQ98486.1 - 3.5e-64 216.7 0.6 6.6e-64 215.7 0.6 1.5 1 0 0 1 1 1 1 Trypsin Ldl_recept_a PF00057.18 KFQ98486.1 - 5.5e-22 77.7 37.3 2.7e-09 37.1 6.6 3.7 2 1 1 3 3 3 3 Low-density lipoprotein receptor domain class A SEA PF01390.20 KFQ98486.1 - 7.8e-20 70.9 0.7 1.4e-19 70.1 0.7 1.4 1 0 0 1 1 1 1 SEA domain CUB PF00431.20 KFQ98486.1 - 4.2e-13 49.6 0.6 1.3e-05 25.5 0.5 2.7 2 0 0 2 2 2 2 CUB domain DUF1986 PF09342.11 KFQ98486.1 - 0.00015 22.2 0.2 0.00055 20.3 0.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 KFQ98486.1 - 0.007 17.3 0.0 0.015 16.2 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain V-set PF07686.17 KFQ98488.1 - 5.5e-08 33.0 0.0 6.1e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFQ98488.1 - 0.00064 19.9 0.1 0.0015 18.6 0.1 1.6 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFQ98488.1 - 0.0042 17.6 0.0 0.0064 17.1 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ98488.1 - 0.0065 16.5 0.0 0.0078 16.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFQ98489.1 - 3.1e-16 59.3 2.2 1.7e-11 44.1 0.5 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 KFQ98489.1 - 4.2e-14 52.9 2.0 6.6e-08 33.1 0.2 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFQ98489.1 - 4e-12 46.0 0.1 3.6e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 KFQ98489.1 - 1.6e-11 44.3 0.6 3e-11 43.5 0.2 1.6 2 0 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFQ98489.1 - 3.1e-05 24.0 0.6 0.00082 19.4 0.1 2.2 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 KFQ98489.1 - 9.3e-05 22.7 3.8 0.0034 17.7 0.6 2.6 2 2 0 2 2 2 1 Immunoglobulin domain C1-set PF07654.15 KFQ98489.1 - 0.00038 20.8 0.2 0.47 10.9 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFQ98489.1 - 0.0028 17.2 0.1 0.007 15.9 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin domain Lep_receptor_Ig PF06328.11 KFQ98489.1 - 0.014 15.4 2.2 2.5 8.1 0.2 2.4 2 1 0 2 2 2 0 Ig-like C2-type domain Ig_4 PF16680.5 KFQ98489.1 - 0.63 10.4 2.5 3 8.2 0.1 2.5 1 1 1 2 2 2 0 T-cell surface glycoprotein CD3 delta chain G6B PF15096.6 KFQ98490.1 - 0.021 14.6 0.1 0.19 11.5 0.0 1.9 1 1 1 2 2 2 0 G6B family AKAP95 PF04988.12 KFQ98491.1 - 0.00013 22.3 0.6 0.00018 21.8 0.6 1.4 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.7 KFQ98491.1 - 0.0034 17.7 1.8 0.0044 17.3 1.1 1.5 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Mut7-C PF01927.16 KFQ98491.1 - 0.011 15.8 1.6 0.36 10.9 0.2 2.2 1 1 1 2 2 2 0 Mut7-C RNAse domain HV_small_capsid PF17086.5 KFQ98491.1 - 0.06 13.6 0.1 0.19 12.0 0.0 1.8 1 1 1 2 2 2 0 Small capsid protein of Herpesviridae ADD_ATRX PF17981.1 KFQ98491.1 - 0.14 12.1 0.1 0.14 12.1 0.1 1.7 2 0 0 2 2 2 0 Cysteine Rich ADD domain zf-C2H2_12 PF18658.1 KFQ98491.1 - 0.23 11.1 1.4 0.37 10.4 0.2 1.9 2 1 1 3 3 3 0 Zinc-finger C2H2-type zf-met PF12874.7 KFQ98491.1 - 2 8.9 6.0 38 4.9 6.0 2.5 1 1 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KFQ98493.1 - 5.8e-08 32.8 39.2 0.022 15.2 1.9 6.2 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ98493.1 - 2.8e-05 24.6 43.4 0.026 15.3 2.6 7.4 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFQ98493.1 - 0.0083 16.4 5.3 0.0083 16.4 5.3 4.6 3 1 1 4 4 4 1 C2H2-type zinc ribbon DUF1178 PF06676.11 KFQ98493.1 - 0.21 12.0 6.0 4.9 7.5 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) zf-met PF12874.7 KFQ98493.1 - 0.29 11.6 13.6 0.52 10.8 0.6 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-MYND PF01753.18 KFQ98493.1 - 7.3 6.8 10.3 2.9 8.1 5.0 3.1 2 0 0 2 2 2 0 MYND finger zf-LYAR PF08790.11 KFQ98493.1 - 8.1 6.4 8.6 18 5.3 0.1 4.0 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger DUF4518 PF15008.6 KFQ98494.1 - 1.6e-91 306.3 0.0 1.9e-91 306.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) Pkinase_Tyr PF07714.17 KFQ98495.1 - 2.1e-99 332.0 0.0 2.4e-99 331.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ98495.1 - 3.3e-49 167.6 0.0 4.2e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.6 KFQ98495.1 - 1.2e-15 58.1 0.1 2.3e-15 57.2 0.1 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Kdo PF06293.14 KFQ98495.1 - 0.003 16.9 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFQ98495.1 - 0.0031 16.5 0.0 0.005 15.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KFQ98495.1 - 0.029 13.2 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Laminin_G_1 PF00054.23 KFQ98496.1 - 1.8e-30 105.9 0.2 9.3e-24 84.1 0.0 2.2 2 0 0 2 2 2 2 Laminin G domain Laminin_G_2 PF02210.24 KFQ98496.1 - 8.7e-22 78.0 0.0 3.6e-13 50.2 0.0 2.2 2 0 0 2 2 2 2 Laminin G domain EGF_CA PF07645.15 KFQ98496.1 - 1.3e-18 66.8 59.0 4.3e-08 33.2 8.7 4.9 4 0 0 4 4 4 4 Calcium-binding EGF domain FXa_inhibition PF14670.6 KFQ98496.1 - 3.2e-17 62.5 58.1 1.9e-08 34.5 11.2 4.6 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site Gla PF00594.20 KFQ98496.1 - 4.3e-16 58.8 9.3 4.3e-16 58.8 9.3 2.4 3 0 0 3 3 3 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain EGF PF00008.27 KFQ98496.1 - 4.8e-12 45.9 51.2 2e-06 28.0 6.2 4.7 4 0 0 4 4 4 3 EGF-like domain cEGF PF12662.7 KFQ98496.1 - 5.3e-11 42.2 41.7 3.8e-06 26.7 4.7 5.5 5 0 0 5 5 5 4 Complement Clr-like EGF-like EGF_3 PF12947.7 KFQ98496.1 - 1.4e-06 28.4 41.2 0.0072 16.5 3.8 4.8 4 0 0 4 4 4 3 EGF domain hEGF PF12661.7 KFQ98496.1 - 7.6e-05 23.2 39.7 0.0076 16.8 4.2 5.3 4 1 1 5 5 5 3 Human growth factor-like EGF LNP1 PF15419.6 KFQ98496.1 - 0.15 12.3 2.4 1.7 8.8 1.5 2.3 2 0 0 2 2 2 0 Leukemia NUP98 fusion partner 1 Arf PF00025.21 KFQ98497.1 - 2.6e-42 144.2 0.8 6.4e-42 143.0 0.0 2.0 2 1 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 KFQ98497.1 - 8e-08 32.5 0.0 2.6e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFQ98497.1 - 1.4e-07 31.3 0.0 2.8e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 Ras family SRPRB PF09439.10 KFQ98497.1 - 5.9e-06 25.8 0.0 5.9e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFQ98497.1 - 2.9e-05 23.4 0.0 2.9e-05 23.4 0.0 3.3 2 2 1 3 3 3 1 G-protein alpha subunit MMR_HSR1 PF01926.23 KFQ98497.1 - 5e-05 23.3 0.4 0.00018 21.6 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Mitofilin PF09731.9 KFQ98497.1 - 0.069 12.0 19.8 0.094 11.5 19.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Syntaxin PF00804.25 KFQ98498.1 - 2.9e-61 206.7 18.9 5e-61 205.9 18.9 1.4 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KFQ98498.1 - 0.001 19.0 1.1 0.0045 16.9 0.0 2.5 3 0 0 3 3 3 1 SNARE domain ALO PF04030.14 KFQ98498.1 - 0.0048 16.7 1.8 0.0062 16.4 0.9 1.5 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase SKA2 PF16740.5 KFQ98498.1 - 0.014 15.2 16.1 0.044 13.6 4.4 3.4 2 2 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Terminase_6C PF17289.2 KFQ98498.1 - 0.016 15.3 2.0 0.13 12.4 0.1 2.4 1 1 1 2 2 2 0 Terminase RNaseH-like domain DUF4988 PF16378.5 KFQ98498.1 - 0.028 14.1 7.3 0.63 9.7 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function HGD-D PF06050.13 KFQ98498.1 - 0.16 11.7 8.8 0.015 15.1 2.5 1.9 1 1 1 2 2 2 0 2-hydroxyglutaryl-CoA dehydratase, D-component Syntaxin-6_N PF09177.11 KFQ98498.1 - 0.58 10.7 13.2 0.074 13.6 2.7 2.8 2 2 0 2 2 2 0 Syntaxin 6, N-terminal DUF948 PF06103.11 KFQ98498.1 - 2.6 8.3 8.3 6.1 7.2 0.3 3.4 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Rx_N PF18052.1 KFQ98498.1 - 2.9 8.2 9.1 4.6 7.6 0.9 2.9 2 1 2 4 4 4 0 Rx N-terminal domain PCRF PF03462.18 KFQ98498.1 - 9.4 6.0 16.4 7.2 6.4 5.2 2.4 2 0 0 2 2 2 0 PCRF domain Methyltr_RsmB-F PF01189.17 KFQ98499.1 - 5.3e-30 104.6 0.0 7.8e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KFQ98499.1 - 0.0022 18.1 0.1 0.013 15.6 0.1 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase Pkinase_Tyr PF07714.17 KFQ98501.1 - 3.5e-95 318.2 0.0 4e-95 318.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ98501.1 - 1.7e-44 152.2 0.0 2.1e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 KFQ98501.1 - 0.0022 17.0 0.0 0.0034 16.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFQ98501.1 - 0.0079 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFQ98501.1 - 0.11 11.2 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Arf PF00025.21 KFQ98502.1 - 1e-54 184.6 0.0 1.2e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KFQ98502.1 - 5.5e-13 48.8 3.6 1.4e-07 31.0 0.6 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KFQ98502.1 - 6.4e-12 45.8 0.0 8.6e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFQ98502.1 - 6.8e-11 42.0 0.0 8e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFQ98502.1 - 1.9e-10 40.5 0.1 2.5e-10 40.1 0.1 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFQ98502.1 - 3.4e-07 29.9 0.1 4e-07 29.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFQ98502.1 - 3.5e-07 30.3 0.0 4.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KFQ98502.1 - 0.0013 19.0 0.1 0.022 15.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 KFQ98502.1 - 0.012 15.2 0.0 0.11 12.0 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KFQ98502.1 - 0.013 15.0 0.1 0.027 14.0 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_18 PF13238.6 KFQ98502.1 - 0.061 13.9 0.0 0.079 13.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFQ98502.1 - 0.12 11.9 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Cupin_4 PF08007.12 KFQ98504.1 - 4.3e-92 309.0 0.0 5.9e-92 308.5 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 KFQ98504.1 - 5.6e-06 26.2 0.1 0.018 14.8 0.1 2.3 1 1 1 2 2 2 2 Cupin-like domain Cupin_2 PF07883.11 KFQ98504.1 - 0.00033 20.3 0.1 0.0094 15.6 0.1 2.3 1 1 0 1 1 1 1 Cupin domain T2SSF PF00482.23 KFQ98504.1 - 0.016 15.2 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F AraC_binding PF02311.19 KFQ98504.1 - 0.092 12.6 0.6 0.31 10.9 0.1 2.2 3 1 0 3 3 3 0 AraC-like ligand binding domain Neur_chan_LBD PF02931.23 KFQ98505.1 - 7.5e-49 166.1 0.3 1.1e-48 165.6 0.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFQ98505.1 - 2.7e-34 119.3 9.5 2.4e-30 106.4 4.4 2.2 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Tmpp129 PF10272.9 KFQ98505.1 - 0.26 10.5 2.4 0.51 9.6 2.4 1.6 1 1 0 1 1 1 0 Putative transmembrane protein precursor CcmD PF04995.14 KFQ98505.1 - 0.79 9.8 3.2 8.3 6.6 0.8 2.5 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF3432 PF11914.8 KFQ98542.1 - 2.5e-36 123.9 39.2 2.5e-36 123.9 39.2 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF3432) DUF3446 PF11928.8 KFQ98542.1 - 1.3e-25 89.5 16.4 1.3e-25 89.5 16.4 4.1 3 1 1 4 4 3 1 Early growth response N-terminal domain zf-H2C2_2 PF13465.6 KFQ98542.1 - 1.9e-21 75.4 26.3 6.4e-08 32.7 0.8 5.2 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ98542.1 - 7.2e-16 57.7 22.9 3.7e-05 23.9 0.3 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ98542.1 - 9e-11 41.7 18.0 0.0094 16.7 0.2 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger Zf_RING PF16744.5 KFQ98542.1 - 0.0095 16.0 2.4 0.27 11.4 0.3 2.4 1 1 1 2 2 2 1 KIAA1045 RING finger zf-C2HC_2 PF13913.6 KFQ98542.1 - 0.04 13.8 11.8 0.21 11.5 0.5 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KFQ98542.1 - 0.042 14.1 5.7 16 5.9 0.0 3.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFQ98542.1 - 0.22 11.3 6.4 27 4.6 0.1 3.7 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-BED PF02892.15 KFQ98542.1 - 0.67 10.0 12.1 0.1 12.7 1.7 3.1 2 1 1 3 3 3 0 BED zinc finger zf-met PF12874.7 KFQ98542.1 - 0.93 10.0 4.3 25 5.5 0.1 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFQ98542.1 - 3.9 7.9 6.3 14 6.1 0.6 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-AN1 PF01428.16 KFQ98542.1 - 4 7.7 5.1 35 4.7 0.2 2.6 2 1 0 2 2 2 0 AN1-like Zinc finger zf-CHY PF05495.12 KFQ98542.1 - 7.1 7.2 9.0 23 5.6 2.2 2.4 1 1 1 2 2 2 0 CHY zinc finger MAPEG PF01124.18 KFQ98543.1 - 0.039 13.8 10.7 3.1 7.7 0.0 2.8 2 1 1 3 3 3 0 MAPEG family Glyco_transf_54 PF04666.13 KFQ98544.1 - 5.5e-137 455.4 0.4 7.3e-137 455.0 0.4 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region STAR_dimer PF16544.5 KFQ98544.1 - 0.33 10.6 2.9 0.18 11.4 0.3 2.0 2 0 0 2 2 2 0 Homodimerisation region of STAR domain protein UBA_5 PF16577.5 KFQ98545.1 - 4.8e-41 138.7 0.1 8.4e-41 137.9 0.1 1.4 1 0 0 1 1 1 1 UBA domain ZZ PF00569.17 KFQ98545.1 - 3.6e-13 49.1 2.8 6.5e-13 48.3 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type PB1 PF00564.24 KFQ98545.1 - 0.00043 20.2 0.0 0.00081 19.3 0.0 1.4 1 0 0 1 1 1 1 PB1 domain C1_2 PF03107.16 KFQ98545.1 - 0.012 15.9 2.4 0.028 14.7 2.4 1.6 1 0 0 1 1 1 0 C1 domain RabGAP-TBC PF00566.18 KFQ98546.1 - 3.7e-48 164.0 0.1 3.7e-48 164.0 0.1 2.4 3 0 0 3 3 3 1 Rab-GTPase-TBC domain GRAM PF02893.20 KFQ98546.1 - 2.4e-42 143.4 0.8 8.4e-23 80.4 0.1 2.5 2 0 0 2 2 2 2 GRAM domain EF-hand_1 PF00036.32 KFQ98546.1 - 0.0017 17.8 1.5 0.0031 16.9 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KFQ98546.1 - 0.041 13.8 0.0 0.17 11.9 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 KFQ98546.1 - 0.07 13.6 0.0 0.37 11.3 0.0 2.3 1 0 0 1 1 1 0 EF-hand domain pair zf-RING_2 PF13639.6 KFQ98547.1 - 9.5e-12 45.1 12.1 1.7e-11 44.2 12.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFQ98547.1 - 2e-09 37.0 4.9 4e-09 36.0 4.9 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFQ98547.1 - 2.7e-08 33.5 12.3 4.8e-08 32.7 12.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ98547.1 - 2.4e-07 30.5 10.9 4.2e-07 29.7 10.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 KFQ98547.1 - 2.9e-07 30.4 0.0 5.5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.7 KFQ98547.1 - 6.6e-07 29.5 10.0 1.4e-06 28.5 10.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFQ98547.1 - 1.4e-06 28.1 9.9 2.3e-06 27.4 9.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFQ98547.1 - 3.8e-05 23.5 9.1 6.8e-05 22.6 9.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFQ98547.1 - 4.2e-05 23.5 7.4 7.6e-05 22.7 7.4 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFQ98547.1 - 0.00016 21.5 8.3 0.00025 20.8 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFQ98547.1 - 0.017 15.2 5.4 0.033 14.2 5.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PspB PF06667.12 KFQ98547.1 - 0.057 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Phage shock protein B AbrB PF05145.12 KFQ98547.1 - 0.071 12.1 0.2 0.11 11.4 0.2 1.3 1 0 0 1 1 1 0 Transition state regulatory protein AbrB Zn_ribbon_17 PF17120.5 KFQ98547.1 - 0.087 12.5 9.9 0.25 11.0 9.9 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Vps39_2 PF10367.9 KFQ98547.1 - 0.24 11.9 0.1 0.24 11.9 0.1 2.6 3 1 1 4 4 4 0 Vacuolar sorting protein 39 domain 2 DUF1180 PF06679.12 KFQ98547.1 - 0.74 10.2 2.1 2.4 8.6 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) zinc_ribbon_16 PF17034.5 KFQ98547.1 - 1.2 9.4 7.1 0.84 9.9 4.5 1.9 1 1 1 2 2 2 0 Zinc-ribbon like family zf-C3H2C3 PF17122.5 KFQ98547.1 - 1.4 9.0 7.3 3 8.0 7.3 1.5 1 0 0 1 1 1 0 Zinc-finger PHD PF00628.29 KFQ98547.1 - 2.1 8.3 10.6 3.6 7.6 10.6 1.4 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 KFQ98547.1 - 2.3 8.4 5.7 5.6 7.1 5.7 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger Pkinase_Tyr PF07714.17 KFQ98548.1 - 1e-109 365.8 0.0 1.6e-109 365.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ig_3 PF13927.6 KFQ98548.1 - 6.3e-55 183.7 15.5 2.3e-11 44.1 0.0 7.2 6 1 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 KFQ98548.1 - 1.4e-43 146.9 8.9 4e-14 52.4 0.1 7.7 6 1 2 8 8 8 4 Immunoglobulin I-set domain Pkinase PF00069.25 KFQ98548.1 - 4.8e-43 147.4 0.0 4.4e-30 104.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Ig_2 PF13895.6 KFQ98548.1 - 2.3e-36 123.9 18.8 2.8e-09 37.2 0.1 9.2 8 2 0 8 8 8 5 Immunoglobulin domain ig PF00047.25 KFQ98548.1 - 4.7e-28 97.2 8.6 5.8e-08 32.8 0.1 6.6 6 0 0 6 6 6 5 Immunoglobulin domain V-set PF07686.17 KFQ98548.1 - 2.9e-21 75.7 16.3 0.00021 21.4 0.2 7.8 6 3 2 8 8 8 6 Immunoglobulin V-set domain VEGFR-2_TMD PF17988.1 KFQ98548.1 - 7.9e-20 70.0 3.7 1.5e-19 69.1 3.7 1.5 1 0 0 1 1 1 1 VEGFR-2 Transmembrane domain Izumo-Ig PF16706.5 KFQ98548.1 - 8e-08 32.2 6.6 2.2 8.4 0.1 6.7 6 2 0 6 6 6 3 Izumo-like Immunoglobulin domain C1-set PF07654.15 KFQ98548.1 - 5.1e-07 30.0 0.7 0.0021 18.4 0.1 4.9 5 0 0 5 5 4 1 Immunoglobulin C1-set domain Ig_5 PF16681.5 KFQ98548.1 - 1.3e-06 28.7 8.0 0.69 10.4 0.0 6.8 6 1 1 7 7 7 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFQ98548.1 - 8.3e-06 25.3 0.6 13 5.5 0.0 5.9 6 0 0 6 6 6 0 Immunoglobulin domain Ig_4 PF16680.5 KFQ98548.1 - 4.2e-05 23.7 9.4 4.5 7.6 0.1 6.1 6 0 0 6 6 6 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFQ98548.1 - 0.00012 22.1 4.4 1.3 9.1 0.0 4.7 5 0 0 5 5 5 1 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.8 KFQ98548.1 - 0.00066 19.8 1.3 0.047 13.9 0.1 3.6 4 0 0 4 4 4 1 Natural killer cell receptor 2B4 Haspin_kinase PF12330.8 KFQ98548.1 - 0.031 13.2 0.1 0.056 12.4 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Herpes_gE PF02480.16 KFQ98548.1 - 0.032 13.0 0.0 2.1 7.0 0.0 2.9 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein E C2-set PF05790.15 KFQ98548.1 - 0.32 11.2 1.9 2 8.6 0.0 3.4 3 0 0 3 3 3 0 Immunoglobulin C2-set domain Adeno_E3_CR1 PF02440.15 KFQ98548.1 - 0.93 9.3 4.3 5.1 7.0 0.1 3.5 3 1 0 3 3 2 0 Adenovirus E3 region protein CR1 7tm_1 PF00001.21 KFQ98549.1 - 5.2e-53 180.0 20.5 6.2e-53 179.8 20.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ98549.1 - 8.1e-12 45.1 18.8 1.2e-11 44.5 18.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFQ98549.1 - 3.1e-07 30.4 15.4 5e-07 29.7 15.4 1.3 1 1 0 1 1 1 1 Olfactory receptor Cyclin_N PF00134.23 KFQ98549.1 - 0.029 14.1 0.9 0.085 12.6 0.1 2.0 2 0 0 2 2 2 0 Cyclin, N-terminal domain HMG_box_2 PF09011.10 KFQ98550.1 - 6.3e-12 45.9 0.4 1.4e-11 44.8 0.4 1.6 1 0 0 1 1 1 1 HMG-box domain CxC4 PF18717.1 KFQ98550.1 - 2.6e-11 43.5 0.1 9.4e-11 41.7 0.1 2.0 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases HMG_box PF00505.19 KFQ98550.1 - 3.4e-11 43.4 0.5 8.2e-11 42.2 0.5 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box Zn_Tnp_IS91 PF14319.6 KFQ98550.1 - 1.7 8.8 5.4 2 8.5 0.7 2.9 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-ribbon_3 PF13248.6 KFQ98550.1 - 2.1 7.8 8.8 5.5 6.5 0.1 3.7 3 0 0 3 3 3 0 zinc-ribbon domain zf-CCCH_2 PF14608.6 KFQ98550.1 - 3.6 8.2 7.2 8.2 7.1 1.2 2.7 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Pkinase_Tyr PF07714.17 KFQ98551.1 - 5.3e-107 356.9 0.0 7.7e-107 356.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ98551.1 - 4e-43 147.7 0.0 6e-27 94.7 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Ig_3 PF13927.6 KFQ98551.1 - 7.6e-26 90.5 4.1 3.9e-06 27.4 0.6 5.6 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 KFQ98551.1 - 5.2e-22 77.7 0.1 0.00032 20.7 0.0 5.9 6 0 0 6 6 5 5 Immunoglobulin I-set domain ig PF00047.25 KFQ98551.1 - 3.3e-18 65.7 4.3 1e-05 25.6 0.2 5.6 5 0 0 5 5 5 4 Immunoglobulin domain Ig_2 PF13895.6 KFQ98551.1 - 1.5e-14 54.1 3.6 1.1e-05 25.6 0.2 5.1 4 1 1 5 5 5 2 Immunoglobulin domain V-set PF07686.17 KFQ98551.1 - 9.9e-08 32.1 5.8 0.024 14.8 0.3 6.7 6 2 1 7 7 7 2 Immunoglobulin V-set domain Ig_4 PF16680.5 KFQ98551.1 - 2.4e-07 30.9 2.0 4.8e-05 23.5 0.0 3.9 4 0 0 4 4 3 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFQ98551.1 - 2.1e-05 24.9 0.3 0.00039 20.8 0.0 3.0 3 0 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFQ98551.1 - 0.0029 17.6 0.1 1.8 8.7 0.0 2.9 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain APH PF01636.23 KFQ98551.1 - 0.0032 17.4 0.0 0.006 16.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family C2-set PF05790.15 KFQ98551.1 - 0.0039 17.4 0.1 0.87 9.8 0.1 3.5 3 0 0 3 3 3 1 Immunoglobulin C2-set domain Haspin_kinase PF12330.8 KFQ98551.1 - 0.11 11.4 0.0 1.1 8.1 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_Tyr PF07714.17 KFQ98552.1 - 3.2e-108 360.9 0.0 4.6e-108 360.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ98552.1 - 3e-44 151.4 0.0 5.5e-27 94.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.6 KFQ98552.1 - 1.8e-28 98.9 7.7 4.1e-10 40.1 0.1 5.7 5 0 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 KFQ98552.1 - 3.3e-27 94.4 4.0 1.4e-09 37.8 0.0 4.9 4 1 0 4 4 4 4 Immunoglobulin I-set domain ig PF00047.25 KFQ98552.1 - 9.3e-23 80.2 4.2 2.9e-08 33.8 0.1 5.8 5 1 0 5 5 5 3 Immunoglobulin domain Ig_2 PF13895.6 KFQ98552.1 - 7.7e-19 67.8 9.9 6.8e-11 42.4 0.1 6.0 5 2 1 6 6 6 3 Immunoglobulin domain C2-set_2 PF08205.12 KFQ98552.1 - 5.3e-06 26.4 8.2 0.045 13.8 0.1 4.9 4 1 0 4 4 4 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFQ98552.1 - 8.1e-06 26.0 11.7 0.0004 20.5 0.7 5.2 5 1 0 5 5 5 1 Immunoglobulin V-set domain Adeno_E3_CR1 PF02440.15 KFQ98552.1 - 0.00017 21.3 0.6 7.4 6.4 0.0 3.8 3 0 0 3 3 3 1 Adenovirus E3 region protein CR1 Ig_5 PF16681.5 KFQ98552.1 - 0.00039 20.8 2.7 0.36 11.3 0.1 4.5 4 2 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Herpes_gE PF02480.16 KFQ98552.1 - 0.0011 17.8 0.9 1.7 7.3 0.1 3.0 2 1 1 3 3 3 2 Alphaherpesvirus glycoprotein E C1-set PF07654.15 KFQ98552.1 - 0.0065 16.8 3.9 2 8.8 0.0 4.6 3 1 0 4 4 4 1 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFQ98552.1 - 0.084 12.5 0.0 0.64 9.6 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin domain Caudal_act PF04731.12 KFQ98553.1 - 4.3e-42 143.7 15.2 7.7e-42 142.9 15.2 1.4 1 0 0 1 1 1 1 Caudal like protein activation region Homeodomain PF00046.29 KFQ98553.1 - 4.5e-21 74.5 2.3 7.6e-21 73.7 2.3 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ98553.1 - 0.0025 17.7 0.4 0.0065 16.3 0.4 1.7 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 KFQ98553.1 - 0.16 11.9 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT SNF PF00209.18 KFQ98554.1 - 8.3e-228 757.3 35.3 9.6e-228 757.1 35.3 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Caveolin PF01146.17 KFQ98554.1 - 3.8 7.5 9.3 0.75 9.7 2.4 2.8 3 0 0 3 3 3 0 Caveolin Phage_holin_2_3 PF16080.5 KFQ98554.1 - 8.8 6.2 7.2 0.46 10.3 0.1 2.5 2 0 0 2 2 2 0 Bacteriophage holin family HP1 Pkinase PF00069.25 KFQ98555.1 - 1.3e-71 241.1 0.0 2e-71 240.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain CaMKII_AD PF08332.10 KFQ98555.1 - 2.8e-64 215.0 0.0 4.5e-64 214.4 0.0 1.3 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain Pkinase_Tyr PF07714.17 KFQ98555.1 - 4.6e-30 104.8 0.0 6.6e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SnoaL_3 PF13474.6 KFQ98555.1 - 1.1e-08 35.4 0.0 1.9e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KFQ98555.1 - 4e-08 33.6 0.0 7.9e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) APH PF01636.23 KFQ98555.1 - 0.0027 17.6 0.4 1.1 9.2 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFQ98555.1 - 0.0038 16.1 0.0 0.0063 15.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFQ98555.1 - 0.0089 15.4 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SnoaL_2 PF12680.7 KFQ98555.1 - 0.045 14.4 0.0 0.095 13.4 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain SnoaL_4 PF13577.6 KFQ98555.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain Sulfatase PF00884.23 KFQ98556.1 - 1.1e-70 238.5 0.1 1.5e-70 238.1 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KFQ98556.1 - 0.014 16.1 0.0 0.21 12.4 0.0 2.4 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase Treacle PF03546.14 KFQ98557.1 - 4.6e-12 45.6 148.7 6.4e-08 31.9 35.8 6.1 1 1 5 6 6 6 4 Treacher Collins syndrome protein Treacle MHCassoc_trimer PF08831.10 KFQ98559.1 - 1e-32 111.9 9.5 1.6e-32 111.3 9.5 1.3 1 0 0 1 1 1 1 Class II MHC-associated invariant chain trimerisation domain MHC2-interact PF09307.10 KFQ98559.1 - 5.4e-32 110.0 3.6 1.1e-31 109.1 3.6 1.5 1 0 0 1 1 1 1 CLIP, MHC2 interacting TssO PF17561.2 KFQ98559.1 - 0.033 14.3 0.2 0.096 12.8 0.0 1.7 2 0 0 2 2 2 0 Type VI secretion system, TssO Ribosomal_S11 PF00411.19 KFQ98560.1 - 3e-45 153.2 0.5 3.7e-45 152.8 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 KFQ98560.1 - 0.072 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) HSNSD PF12062.8 KFQ98561.1 - 1.2e-257 855.5 0.0 1.5e-257 855.1 0.0 1.1 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.27 KFQ98561.1 - 2e-46 158.7 0.0 3.2e-46 158.0 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFQ98561.1 - 1.4e-06 28.8 0.3 0.0056 17.1 0.0 2.5 1 1 1 2 2 2 2 Sulfotransferase family Calsarcin PF05556.11 KFQ98562.1 - 4e-37 128.1 0.0 1.7e-36 126.1 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) RRM_1 PF00076.22 KFQ98563.1 - 2.9e-11 43.0 0.1 4.6e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KFQ98563.1 - 2.8e-06 27.2 1.8 2.8e-06 27.2 1.8 2.1 2 0 0 2 2 2 1 Zinc finger domain Torus PF16131.5 KFQ98563.1 - 4.1e-06 27.4 0.2 1.4e-05 25.8 0.0 1.9 2 0 0 2 2 2 1 Torus domain Nup35_RRM_2 PF14605.6 KFQ98563.1 - 2.2e-05 24.4 0.0 4.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KFQ98563.1 - 0.00018 21.3 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif zf-CCCH PF00642.24 KFQ98563.1 - 0.0019 18.0 1.8 0.0019 18.0 1.8 2.6 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.11 KFQ98563.1 - 0.0021 18.0 0.0 0.0049 16.9 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif zf-CCCH_4 PF18044.1 KFQ98563.1 - 0.0056 16.4 1.8 0.013 15.3 1.8 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KFQ98563.1 - 0.0094 16.2 0.6 0.02 15.1 0.2 1.7 2 0 0 2 2 2 1 Zinc-finger containing family FYVE PF01363.21 KFQ98563.1 - 0.0099 16.0 0.6 0.0099 16.0 0.6 1.7 2 0 0 2 2 2 1 FYVE zinc finger zf-CCCH_2 PF14608.6 KFQ98563.1 - 0.012 16.1 0.5 0.012 16.1 0.5 2.1 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zinc-ribbons_6 PF07191.12 KFQ98563.1 - 1.9 8.5 9.2 4.5 7.3 9.2 1.6 1 0 0 1 1 1 0 zinc-ribbons Dynactin_p62 PF05502.13 KFQ98564.1 - 8.8e-37 127.0 22.5 8.2e-21 74.3 14.2 2.5 1 1 1 2 2 2 2 Dynactin p62 family GSHPx PF00255.19 KFQ98565.1 - 2.3e-06 27.1 0.0 2.6e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase GSHPx PF00255.19 KFQ98566.1 - 7.3e-24 83.4 0.1 9.8e-24 83.0 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase CC2-LZ PF16516.5 KFQ98567.1 - 5e-08 33.2 20.6 5e-08 33.2 20.6 6.6 3 2 2 5 5 5 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Ribosomal_L12_N PF16320.5 KFQ98567.1 - 0.032 13.9 0.0 0.099 12.4 0.0 1.9 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain GLE1 PF07817.13 KFQ98567.1 - 0.8 8.9 8.4 0.042 13.0 0.9 2.6 2 1 0 3 3 3 0 GLE1-like protein Annexin PF00191.20 KFQ98568.1 - 1.8e-188 610.9 33.6 4.5e-25 87.5 0.4 8.1 8 0 0 8 8 8 8 Annexin DUF5069 PF16798.5 KFQ98568.1 - 0.0022 18.2 0.0 0.86 9.8 0.0 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF5069) GGDEF_2 PF17853.1 KFQ98568.1 - 0.0029 17.8 0.2 0.04 14.2 0.1 3.0 3 1 0 3 3 3 1 GGDEF-like domain Myb_DNA-bind_7 PF15963.5 KFQ98568.1 - 0.0031 17.4 0.5 12 5.9 0.0 5.8 8 0 0 8 8 8 1 Myb DNA-binding like Sigma70_ner PF04546.13 KFQ98568.1 - 0.0053 16.7 4.2 14 5.5 0.0 3.8 2 1 2 4 4 4 2 Sigma-70, non-essential region RuvC PF02075.17 KFQ98568.1 - 0.017 15.0 0.1 21 5.0 0.0 3.6 4 0 0 4 4 4 0 Crossover junction endodeoxyribonuclease RuvC DUF2255 PF10012.9 KFQ98568.1 - 0.77 9.9 3.2 76 3.5 0.1 3.8 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2255) AA_permease_2 PF13520.6 KFQ98569.1 - 4.2e-46 157.6 25.4 4.2e-46 157.6 25.4 2.1 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 KFQ98569.1 - 2.7e-38 131.8 25.1 2.7e-38 131.8 25.1 2.1 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 KFQ98569.1 - 1e-19 70.3 8.7 1e-19 70.3 8.7 3.8 4 0 0 4 4 4 1 C-terminus of AA_permease FapA PF03961.13 KFQ98570.1 - 0.045 12.4 8.1 0.049 12.2 8.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1690 PF07956.11 KFQ98570.1 - 0.051 14.0 11.7 0.025 15.0 9.4 1.6 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Lambda_tail_I PF06805.12 KFQ98570.1 - 0.11 12.9 0.1 0.26 11.6 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage lambda tail assembly protein I FAM184 PF15665.5 KFQ98570.1 - 0.15 11.8 17.5 0.24 11.1 17.5 1.4 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B DUF3810 PF12725.7 KFQ98570.1 - 0.2 11.0 1.5 0.22 10.9 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Nuc_N PF14448.6 KFQ98570.1 - 0.33 10.8 4.7 0.7 9.8 1.3 2.8 1 1 1 2 2 2 0 Nuclease N terminal Spectrin PF00435.21 KFQ98570.1 - 0.55 10.8 13.9 0.39 11.2 11.3 2.0 1 1 1 2 2 2 0 Spectrin repeat DUF4140 PF13600.6 KFQ98570.1 - 0.68 10.4 12.7 1.9 9.0 1.0 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) TMPIT PF07851.13 KFQ98570.1 - 3.2 6.9 7.1 4 6.6 7.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein Matrilin_ccoil PF10393.9 KFQ98570.1 - 3.9 7.4 7.0 0.4 10.6 1.7 1.9 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF1707 PF08044.11 KFQ98570.1 - 4.4 7.5 12.5 1.9 8.6 2.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) DUF5320 PF17253.2 KFQ98570.1 - 8.4 7.5 6.8 58 4.8 6.8 2.2 1 1 0 1 1 1 0 Family of unknown function (DUF5320) E1_DerP2_DerF2 PF02221.15 KFQ98571.1 - 3.4e-27 95.5 0.1 4.1e-27 95.2 0.1 1.1 1 0 0 1 1 1 1 ML domain DUF1970 PF09301.10 KFQ98571.1 - 0.032 14.5 0.1 0.84 9.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1970) Aa_trans PF01490.18 KFQ98572.1 - 1.8e-72 244.4 28.0 2e-72 244.1 28.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Cadherin PF00028.17 KFQ98573.1 - 0 1580.6 44.5 6.1e-22 77.9 0.0 33.7 34 0 0 34 34 34 33 Cadherin domain Cadherin_2 PF08266.12 KFQ98573.1 - 1.1e-21 76.4 0.0 0.48 10.3 0.0 18.0 22 0 0 22 22 22 3 Cadherin-like Cadherin_3 PF16184.5 KFQ98573.1 - 3e-19 69.1 47.0 0.056 13.4 0.1 19.8 23 0 0 23 23 23 5 Cadherin-like Laminin_G_2 PF02210.24 KFQ98573.1 - 1e-17 64.9 0.1 4e-17 63.0 0.1 2.2 1 0 0 1 1 1 1 Laminin G domain RET_CLD1 PF17756.1 KFQ98573.1 - 1.6e-15 57.5 0.0 0.33 11.2 0.0 13.6 17 1 1 18 18 17 1 RET Cadherin like domain 1 Laminin_G_1 PF00054.23 KFQ98573.1 - 7.4e-12 45.6 0.0 3e-11 43.6 0.0 2.1 1 0 0 1 1 1 1 Laminin G domain EGF PF00008.27 KFQ98573.1 - 9.6e-12 45.0 40.3 3.7e-05 23.9 8.4 3.6 3 0 0 3 3 3 3 EGF-like domain Laminin_G_3 PF13385.6 KFQ98573.1 - 0.0012 19.0 0.2 0.016 15.3 0.0 2.8 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Cadherin_4 PF17803.1 KFQ98573.1 - 0.007 17.0 98.0 0.09 13.4 1.2 19.2 20 0 0 20 20 19 2 Bacterial cadherin-like domain EGF_2 PF07974.13 KFQ98573.1 - 0.034 14.5 44.5 0.033 14.6 11.4 3.7 3 0 0 3 3 3 0 EGF-like domain Hint PF01079.20 KFQ98573.1 - 0.074 12.6 0.1 0.76 9.2 0.0 2.5 3 0 0 3 3 3 0 Hint module Podovirus_Gp16 PF05894.12 KFQ98573.1 - 0.11 12.0 0.2 18 4.6 0.0 3.4 4 0 0 4 4 4 0 Podovirus DNA encapsidation protein (Gp16) hEGF PF12661.7 KFQ98573.1 - 1.6 9.5 32.3 1.4 9.6 7.7 3.9 3 0 0 3 3 3 0 Human growth factor-like EGF DUF4394 PF14339.6 KFQ98573.1 - 4.3 6.6 8.7 4.1 6.7 0.1 5.2 7 0 0 7 7 7 0 Domain of unknown function (DUF4394) He_PIG PF05345.12 KFQ98573.1 - 5.5 7.2 17.8 38 4.6 0.1 9.0 9 0 0 9 9 9 0 Putative Ig domain SPARC_Ca_bdg PF10591.9 KFQ98574.1 - 3.8e-41 140.0 0.6 8.4e-41 138.8 0.6 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_1 PF00050.21 KFQ98574.1 - 1.6e-15 56.9 7.3 1.3e-14 53.9 4.9 2.7 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KFQ98574.1 - 3.8e-12 46.1 2.6 3.8e-12 46.1 2.6 3.0 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain FOLN PF09289.10 KFQ98574.1 - 6.7e-09 35.8 9.6 6.7e-09 35.8 9.6 2.2 3 0 0 3 3 3 1 Follistatin/Osteonectin-like EGF domain EF-hand_1 PF00036.32 KFQ98574.1 - 0.026 14.1 0.2 0.2 11.3 0.1 2.4 2 1 0 2 2 2 0 EF hand DUF4801 PF16059.5 KFQ98574.1 - 0.05 13.6 7.8 0.14 12.2 7.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4801) hEGF PF12661.7 KFQ98574.1 - 0.17 12.6 2.6 0.61 10.8 2.6 2.0 1 1 0 1 1 1 0 Human growth factor-like EGF HMA PF00403.26 KFQ98575.1 - 2.6e-10 40.6 0.1 2.9e-10 40.4 0.1 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain RXLR_WY PF18634.1 KFQ98575.1 - 0.12 12.4 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 RXLR phytopathogen effector protein WY-domain NTF2 PF02136.20 KFQ98576.1 - 3.1e-26 92.3 0.4 5.5e-26 91.5 0.4 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KFQ98576.1 - 2.1e-13 49.9 0.0 3.7e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFQ98576.1 - 0.00021 21.3 0.0 0.0011 19.0 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif Neur_chan_LBD PF02931.23 KFQ98577.1 - 1e-53 182.0 0.0 1.3e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFQ98577.1 - 3.2e-40 138.7 1.1 1.1e-33 117.3 0.1 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region 7tm_1 PF00001.21 KFQ98578.1 - 1.2e-50 172.3 17.5 1.8e-50 171.7 17.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ98578.1 - 1.3e-09 37.8 17.3 2.8e-09 36.8 17.3 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 KFQ98578.1 - 0.00012 21.5 17.1 0.0046 16.3 17.1 2.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 KFQ98578.1 - 0.00021 21.0 25.1 0.0007 19.3 23.9 2.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFQ98578.1 - 0.00036 20.4 15.4 0.0024 17.7 15.4 2.1 1 1 0 1 1 1 1 Olfactory receptor HRG PF16954.5 KFQ98578.1 - 0.083 13.3 0.4 0.083 13.3 0.4 2.7 3 0 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene HTH_11 PF08279.12 KFQ98578.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 HTH domain Sigma_reg_N PF13800.6 KFQ98578.1 - 6 7.2 7.4 6.5 7.1 0.1 3.6 3 1 0 3 3 3 0 Sigma factor regulator N-terminal YGGT PF02325.17 KFQ98578.1 - 8.6 6.9 13.0 0.23 11.9 4.3 2.8 3 0 0 3 3 3 0 YGGT family ANF_receptor PF01094.28 KFQ98579.1 - 6.6e-69 232.7 0.0 9.8e-69 232.1 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 KFQ98579.1 - 1.4e-59 200.2 0.0 2.2e-59 199.6 0.0 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFQ98579.1 - 1.1e-44 151.3 0.0 3e-44 149.9 0.0 1.8 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFQ98579.1 - 3.8e-24 85.4 0.0 7.6e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF659 PF04937.15 KFQ98579.1 - 0.0038 17.1 0.1 0.011 15.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Ion_trans_2 PF07885.16 KFQ98579.1 - 2.8 8.0 7.1 4.7 7.2 0.1 3.6 3 0 0 3 3 3 0 Ion channel LON_substr_bdg PF02190.16 KFQ98580.1 - 6.2e-23 81.8 0.0 8e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KFQ98580.1 - 1e-09 38.1 14.7 1e-09 38.1 14.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFQ98580.1 - 2.6e-09 36.8 10.1 6.2e-09 35.6 10.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ98580.1 - 3.7e-07 29.9 16.4 6e-07 29.2 14.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFQ98580.1 - 4.6e-07 30.1 14.3 4.6e-07 30.1 14.3 2.4 3 0 0 3 3 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KFQ98580.1 - 5.2e-07 29.6 10.6 2.1e-06 27.6 8.8 2.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFQ98580.1 - 2.6e-06 27.3 13.5 7.9e-06 25.7 13.5 1.9 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFQ98580.1 - 8.6e-06 25.5 11.1 2.1e-05 24.3 11.1 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFQ98580.1 - 4.6e-05 23.5 10.6 0.0002 21.4 10.6 2.1 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KFQ98580.1 - 0.00075 19.6 7.3 0.0019 18.3 7.3 1.7 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KFQ98580.1 - 0.0025 18.1 11.7 0.0074 16.6 11.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain U-box PF04564.15 KFQ98580.1 - 0.0075 16.4 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-RING_6 PF14835.6 KFQ98580.1 - 0.082 12.8 9.7 0.19 11.6 9.7 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KFQ98580.1 - 2 8.2 13.2 5.1 7.0 12.4 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF719 PF05334.13 KFQ98581.1 - 2.6e-71 239.8 2.4 2.6e-71 239.8 2.4 3.2 3 1 1 4 4 4 1 Protein of unknown function (DUF719) RLL PF10036.9 KFQ98581.1 - 2.2 8.0 8.5 0.15 11.9 2.9 2.0 2 1 0 2 2 2 0 RNA transcription, translation and transport factor protein ig PF00047.25 KFQ98582.1 - 9.5e-08 32.1 0.0 1.7e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ98582.1 - 6.3e-07 29.4 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ98582.1 - 2.3e-06 28.1 0.0 5.7e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFQ98582.1 - 5.3e-05 23.3 0.1 0.0044 17.2 0.1 2.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KFQ98582.1 - 0.015 15.6 0.0 0.034 14.5 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Izumo-Ig PF16706.5 KFQ98582.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain SAP30_Sin3_bdg PF13867.6 KFQ98583.1 - 3.5e-26 91.3 0.7 6.5e-26 90.4 0.7 1.5 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 zf-SAP30 PF13866.6 KFQ98583.1 - 6.8e-13 48.5 2.0 6.8e-13 48.5 2.0 1.7 2 0 0 2 2 2 1 SAP30 zinc-finger HLH PF00010.26 KFQ98584.1 - 2.5e-17 62.6 0.0 4.2e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_51 PF18558.1 KFQ98584.1 - 0.011 15.6 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain La PF05383.17 KFQ98585.1 - 1.4e-21 76.3 0.8 3.5e-21 75.0 0.2 2.1 2 0 0 2 2 2 1 La domain DUF5320 PF17253.2 KFQ98585.1 - 0.024 15.7 2.4 0.094 13.8 0.9 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5320) SGP PF17228.2 KFQ98585.1 - 6 7.8 12.6 0.28 12.0 6.2 2.1 2 0 0 2 2 2 0 Sulphur globule protein FA_hydroxylase PF04116.13 KFQ98586.1 - 7.2e-21 74.9 14.9 7.2e-21 74.9 14.9 2.7 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily TRP_2 PF08344.11 KFQ98586.1 - 0.17 12.1 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 Transient receptor ion channel II CAF1 PF04857.20 KFQ98587.1 - 1.5e-23 83.5 1.6 1.1e-11 44.5 0.1 2.4 1 1 0 2 2 2 2 CAF1 family ribonuclease ANAPC4_WD40 PF12894.7 KFQ98588.1 - 2.2e-25 88.8 1.3 6.9e-07 29.5 0.0 6.8 5 2 2 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFQ98588.1 - 7.7e-21 74.0 38.6 8.9e-05 23.2 0.3 12.7 12 2 0 12 12 12 6 WD domain, G-beta repeat Nup160 PF11715.8 KFQ98588.1 - 0.00079 18.2 0.0 0.56 8.8 0.0 3.2 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Ribosomal_L22 PF00237.19 KFQ98589.1 - 1.9e-23 82.6 0.8 2.9e-23 82.1 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Sarcoglycan_1 PF04790.13 KFQ98590.1 - 1.3e-81 273.8 0.0 1.5e-81 273.6 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2345 PF10106.9 KFQ98590.1 - 0.00039 20.3 0.1 0.0035 17.2 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2345) DUF1523 PF07509.11 KFQ98590.1 - 0.08 12.3 0.1 0.17 11.2 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1523) V-set PF07686.17 KFQ98591.1 - 1e-17 64.3 0.1 1.7e-17 63.5 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFQ98591.1 - 0.0014 18.8 0.0 0.011 15.9 0.0 2.3 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFQ98591.1 - 0.021 15.1 1.0 0.32 11.4 1.0 2.3 1 1 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFQ98591.1 - 0.025 14.6 0.0 0.053 13.6 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ98591.1 - 0.028 15.0 1.0 0.32 11.6 0.5 2.9 2 1 0 2 2 2 0 Immunoglobulin domain Receptor_2B4 PF11465.8 KFQ98591.1 - 0.03 14.5 0.0 0.07 13.3 0.0 1.6 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 V-set PF07686.17 KFQ98592.1 - 1.1e-13 51.3 1.1 3.5e-13 49.7 0.3 2.1 2 1 0 2 2 2 1 Immunoglobulin V-set domain ig PF00047.25 KFQ98592.1 - 2.7e-06 27.5 0.0 8.7e-05 22.6 0.0 2.5 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ98592.1 - 0.001 19.1 0.1 0.0035 17.4 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin I-set domain Endomucin PF07010.12 KFQ98592.1 - 0.002 18.1 0.4 0.0028 17.7 0.4 1.1 1 0 0 1 1 1 1 Endomucin Ig_2 PF13895.6 KFQ98592.1 - 0.004 17.4 1.8 0.013 15.8 0.7 2.4 1 1 1 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 KFQ98592.1 - 0.013 16.0 4.1 0.015 15.9 0.5 2.7 2 2 0 2 2 2 0 Immunoglobulin domain Receptor_2B4 PF11465.8 KFQ98592.1 - 0.11 12.7 0.1 0.51 10.6 0.0 2.1 2 1 1 3 3 3 0 Natural killer cell receptor 2B4 Med7 PF05983.11 KFQ98593.1 - 3.9e-46 157.6 7.7 3.1e-45 154.6 7.7 1.9 1 1 0 1 1 1 1 MED7 protein DotU PF09850.9 KFQ98593.1 - 0.52 10.0 2.3 9.1 5.9 0.5 2.2 2 0 0 2 2 2 0 Type VI secretion system protein DotU Pkinase_Tyr PF07714.17 KFQ98594.1 - 5.8e-92 307.6 0.0 7.9e-92 307.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ98594.1 - 2.1e-50 171.5 0.0 3.2e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFQ98594.1 - 2.2e-21 75.7 0.0 4.7e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFQ98594.1 - 3.8e-15 55.2 0.3 8.2e-15 54.2 0.3 1.6 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 KFQ98594.1 - 1.8e-13 50.9 0.4 5.3e-13 49.4 0.4 1.8 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.6 KFQ98594.1 - 2e-13 50.0 0.3 4.4e-13 48.9 0.3 1.7 1 0 0 1 1 1 1 Variant SH3 domain BTK PF00779.19 KFQ98594.1 - 9e-13 47.8 3.4 1.6e-12 47.0 3.4 1.5 1 0 0 1 1 1 1 BTK motif SH3_2 PF07653.17 KFQ98594.1 - 2.6e-07 30.2 0.0 5.6e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFQ98594.1 - 4.7e-05 23.6 0.2 0.00014 22.0 0.2 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_10 PF17902.1 KFQ98594.1 - 0.00015 21.7 0.0 0.00043 20.3 0.0 1.8 1 0 0 1 1 1 1 SH3 domain PH_8 PF15409.6 KFQ98594.1 - 0.00089 19.5 0.3 0.0038 17.5 0.3 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_4 PF06347.13 KFQ98594.1 - 0.016 15.0 0.1 0.036 13.9 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain RFC1 PF08519.12 KFQ98594.1 - 0.018 15.2 0.0 0.043 14.0 0.0 1.6 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain Neprosin PF03080.15 KFQ98594.1 - 0.045 13.1 0.2 0.13 11.6 0.1 1.8 2 0 0 2 2 2 0 Neprosin Kinase-like PF14531.6 KFQ98594.1 - 0.12 11.7 0.0 0.51 9.6 0.0 1.9 2 0 0 2 2 2 0 Kinase-like PH_11 PF15413.6 KFQ98594.1 - 0.65 10.4 3.8 1.1 9.7 1.5 2.6 2 1 0 2 2 1 0 Pleckstrin homology domain fn3 PF00041.21 KFQ98595.1 - 3.1e-05 24.2 0.2 4.7e-05 23.6 0.2 1.3 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFQ98595.1 - 0.051 14.1 0.1 0.09 13.4 0.1 1.4 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Reprolysin PF01421.19 KFQ98596.1 - 4.6e-64 216.0 0.0 4.6e-64 216.0 0.0 1.7 2 0 0 2 2 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.12 KFQ98596.1 - 5.5e-32 110.6 7.5 5.5e-32 110.6 7.5 3.7 3 1 1 4 4 2 1 ADAM cysteine-rich Pep_M12B_propep PF01562.19 KFQ98596.1 - 5.1e-26 91.6 0.2 1.3e-25 90.2 0.2 1.7 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_5 PF13688.6 KFQ98596.1 - 2.2e-24 86.7 1.2 6.4e-24 85.2 1.2 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12 Disintegrin PF00200.23 KFQ98596.1 - 2.2e-19 70.0 26.8 2.2e-19 70.0 26.8 4.7 4 1 0 4 4 3 1 Disintegrin Reprolysin_3 PF13582.6 KFQ98596.1 - 2.4e-16 60.4 0.1 5.8e-16 59.1 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFQ98596.1 - 7.2e-12 45.6 0.2 1.7e-11 44.4 0.2 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFQ98596.1 - 8.5e-11 41.9 0.2 1.6e-10 41.0 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.13 KFQ98596.1 - 0.003 17.9 13.9 0.003 17.9 13.9 6.5 6 2 0 6 6 3 1 EGF-like domain Peptidase_M66 PF10462.9 KFQ98596.1 - 0.03 13.3 0.3 0.052 12.5 0.3 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M54 PF07998.11 KFQ98596.1 - 0.14 12.1 0.2 0.35 10.8 0.2 1.6 1 0 0 1 1 1 0 Peptidase family M54 HMG_box PF00505.19 KFQ98597.1 - 4.2e-23 81.5 1.3 7.2e-23 80.8 1.3 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFQ98597.1 - 1.4e-10 41.6 0.5 2.4e-10 40.8 0.5 1.3 1 0 0 1 1 1 1 HMG-box domain Thg1 PF04446.12 KFQ98598.1 - 1.9e-51 173.3 0.5 2.9e-51 172.7 0.5 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KFQ98598.1 - 9.7e-50 167.8 0.3 1.7e-49 167.0 0.3 1.4 1 0 0 1 1 1 1 Thg1 C terminal domain LSM PF01423.22 KFQ98599.1 - 6.4e-10 38.6 0.1 5.4e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 LSM domain ENTH PF01417.20 KFQ98600.1 - 2.2e-45 153.7 0.0 4.1e-45 152.8 0.0 1.5 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KFQ98600.1 - 3.8e-05 22.8 0.0 6.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 ANTH domain COE1_DBD PF16422.5 KFQ98601.1 - 2e-72 243.4 5.6 2.8e-72 242.9 5.6 1.2 1 0 0 1 1 1 1 Transcription factor COE1 DNA-binding domain COE1_HLH PF16423.5 KFQ98601.1 - 6.7e-37 124.9 3.0 4.3e-30 103.1 0.4 2.5 2 0 0 2 2 2 2 Transcription factor COE1 helix-loop-helix domain TIG PF01833.24 KFQ98601.1 - 3.7e-12 46.1 0.3 3.7e-12 46.1 0.3 2.4 3 0 0 3 3 3 1 IPT/TIG domain HLH PF00010.26 KFQ98601.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain TRC8_N PF13705.6 KFQ98602.1 - 3.3e-154 514.5 46.6 4e-154 514.2 46.6 1.1 1 0 0 1 1 1 1 TRC8 N-terminal domain zf-RING_2 PF13639.6 KFQ98602.1 - 5.4e-10 39.5 7.2 5.4e-10 39.5 7.2 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFQ98602.1 - 3.8e-09 36.2 7.2 9.5e-09 35.0 7.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFQ98602.1 - 8.5e-08 32.4 7.2 2.1e-07 31.1 7.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFQ98602.1 - 1.3e-06 28.3 1.2 1.3e-06 28.3 1.2 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFQ98602.1 - 4.2e-06 26.5 6.5 4.2e-06 26.5 6.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFQ98602.1 - 7.7e-06 25.7 8.7 7.7e-06 25.7 8.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFQ98602.1 - 3.7e-05 23.5 8.7 3.7e-05 23.5 8.7 1.6 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KFQ98602.1 - 0.00018 21.1 4.4 0.00018 21.1 4.4 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KFQ98602.1 - 0.0025 17.8 10.4 0.0025 17.8 10.4 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KFQ98602.1 - 0.015 15.3 7.0 0.039 14.0 7.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFQ98602.1 - 0.52 10.0 15.0 0.11 12.2 8.4 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-P11 PF03854.14 KFQ98602.1 - 0.89 9.3 7.7 3.3 7.5 7.7 2.0 1 0 0 1 1 1 0 P-11 zinc finger NIF PF03031.18 KFQ98603.1 - 1.7e-30 105.8 0.2 2.6e-30 105.2 0.2 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 KFQ98603.1 - 7e-08 32.1 0.1 1.6e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family DUF705 PF05152.12 KFQ98603.1 - 0.0017 17.9 0.1 0.0028 17.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF705) Ubiquitin_2 PF14560.6 KFQ98603.1 - 0.013 16.0 0.1 0.034 14.6 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain Kazal_1 PF00050.21 KFQ98604.1 - 2.7e-17 62.5 4.6 3.1e-17 62.3 4.6 1.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KFQ98604.1 - 5.8e-09 35.9 2.7 7.5e-09 35.6 2.7 1.2 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFQ98605.1 - 2e-13 50.1 5.4 3.1e-13 49.5 5.4 1.2 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KFQ98605.1 - 0.00012 22.1 2.4 0.00012 22.1 2.4 1.5 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Uteroglobin PF01099.17 KFQ98605.1 - 0.024 15.0 1.0 0.024 15.0 1.0 1.5 2 0 0 2 2 2 0 Uteroglobin family Kazal_1 PF00050.21 KFQ98606.1 - 5.3e-55 183.2 29.7 8.8e-20 70.5 5.0 3.1 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KFQ98606.1 - 1.2e-28 99.0 27.3 9.3e-11 41.7 2.9 3.4 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain MDM10 PF12519.8 KFQ98606.1 - 0.011 14.7 0.0 0.014 14.3 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Uteroglobin PF01099.17 KFQ98606.1 - 0.12 12.7 1.4 0.9 9.9 0.1 2.3 2 0 0 2 2 2 0 Uteroglobin family Kazal_1 PF00050.21 KFQ98607.1 - 1.2e-113 371.0 62.8 4.7e-20 71.3 4.0 6.1 6 0 0 6 6 6 6 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KFQ98607.1 - 9.1e-63 208.2 50.5 1.7e-11 44.1 2.3 6.3 6 0 0 6 6 6 6 Kazal-type serine protease inhibitor domain DUF4260 PF14079.6 KFQ98607.1 - 0.016 15.2 0.0 5.8 6.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4260) Ribosomal_L37e PF01907.19 KFQ98616.1 - 8.9e-21 73.8 11.3 1.7e-20 72.9 11.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 KFQ98616.1 - 0.017 15.2 2.2 0.025 14.6 2.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon FeS PF04060.13 KFQ98616.1 - 0.41 10.4 4.0 0.48 10.1 0.7 2.1 2 0 0 2 2 2 0 Putative Fe-S cluster DUF2688 PF10892.8 KFQ98616.1 - 1.7 8.2 5.3 1 8.8 2.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) CBX7_C PF17218.3 KFQ98643.1 - 2.1e-13 49.7 1.9 3e-13 49.2 1.9 1.3 1 0 0 1 1 1 1 CBX family C-terminal motif CBX7_C PF17218.3 KFQ98644.1 - 5.9e-15 54.7 2.3 9.8e-15 54.0 2.3 1.4 1 0 0 1 1 1 1 CBX family C-terminal motif Chromo PF00385.24 KFQ98644.1 - 3.5e-12 46.0 0.5 3.5e-12 46.0 0.5 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RBR PF17208.3 KFQ98644.1 - 1.2e-05 25.9 4.2 0.048 14.4 1.9 2.7 2 0 0 2 2 2 2 RNA binding Region VirC1 PF07015.11 KFQ98644.1 - 0.29 10.4 0.2 0.45 9.8 0.2 1.2 1 0 0 1 1 1 0 VirC1 protein CBX7_C PF17218.3 KFQ98645.1 - 5.1e-13 48.5 0.8 1.3e-12 47.2 0.8 1.7 1 0 0 1 1 1 1 CBX family C-terminal motif RabGAP-TBC PF00566.18 KFQ98646.1 - 6.7e-47 159.9 1.7 1.1e-46 159.2 1.7 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 KFQ98646.1 - 8.3e-07 28.6 0.1 0.047 13.2 0.0 2.3 2 0 0 2 2 2 2 Rab-binding domain (RBD) BRE1 PF08647.11 KFQ98647.1 - 1.7e-14 53.6 11.9 1.7e-14 53.6 11.9 11.9 6 5 7 13 13 13 2 BRE1 E3 ubiquitin ligase SNCAIP_SNCA_bd PF16700.5 KFQ98647.1 - 1.6 8.5 7.7 0.71 9.6 0.3 3.7 2 1 1 3 3 3 0 Synphilin-1 alpha-Synuclein-binding domain Sulfatase PF00884.23 KFQ98648.1 - 2.2e-50 171.8 0.0 6.5e-50 170.3 0.0 1.7 1 1 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KFQ98648.1 - 5.8e-09 36.1 0.4 1.5e-07 31.6 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KFQ98648.1 - 1.8e-07 31.1 0.0 6.5e-06 26.0 0.0 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 KFQ98648.1 - 0.0026 18.5 0.3 0.0052 17.5 0.3 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF1501 PF07394.12 KFQ98648.1 - 0.036 13.1 0.0 0.14 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) Sulfate_transp PF00916.20 KFQ98649.1 - 3.8e-72 243.2 10.0 4.9e-72 242.8 10.0 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFQ98649.1 - 1.9e-11 43.6 0.0 3.4e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KFQ98649.1 - 0.00049 20.4 0.7 0.00049 20.4 0.7 2.1 2 0 0 2 2 2 1 STAS domain DUF2408 PF10303.9 KFQ98650.1 - 0.0038 17.8 3.1 0.26 11.9 0.5 3.2 2 1 0 2 2 2 2 Protein of unknown function (DUF2408) Mustang PF15682.5 KFQ98651.1 - 0.051 13.7 0.0 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 Musculoskeletal, temporally activated-embryonic nuclear protein 1 DUF1400 PF07176.11 KFQ98652.1 - 0.59 10.4 7.0 0.38 11.1 0.1 3.8 4 1 0 4 4 4 0 Alpha/beta hydrolase of unknown function (DUF1400) Endonuclease_5 PF04493.14 KFQ98653.1 - 2.8e-66 223.0 0.0 3.1e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 Endonuclease V UvrC_HhH_N PF08459.11 KFQ98653.1 - 0.019 14.9 0.0 0.05 13.5 0.0 1.6 1 1 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal Pentaxin PF00354.17 KFQ98654.1 - 2e-34 119.0 0.0 3e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.6 KFQ98654.1 - 2.2e-16 60.4 0.0 3.2e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Pox_A_type_inc PF04508.12 KFQ98654.1 - 0.0059 16.4 0.3 6.9 6.7 0.0 3.0 2 0 0 2 2 2 2 Viral A-type inclusion protein repeat Laminin_G_2 PF02210.24 KFQ98654.1 - 0.0076 16.8 0.0 0.013 16.0 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain DUF3024 PF11225.8 KFQ98654.1 - 0.072 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3024) DUF848 PF05852.11 KFQ98654.1 - 0.081 13.0 1.8 0.9 9.6 0.4 2.2 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) SlyX PF04102.12 KFQ98654.1 - 0.44 11.2 7.9 0.65 10.7 1.0 3.0 2 1 1 3 3 3 0 SlyX DUF3450 PF11932.8 KFQ98654.1 - 0.66 9.2 5.7 0.35 10.1 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF16 PF01519.16 KFQ98654.1 - 1 9.9 4.6 19 5.8 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF1664 PF07889.12 KFQ98654.1 - 1.6 8.8 6.1 5 7.2 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 KFQ98654.1 - 2.6 8.1 11.1 0.2 11.7 2.3 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 KFQ98654.1 - 5.5 6.8 6.2 6.6 6.6 0.4 2.8 2 1 1 3 3 3 0 Septum formation initiator TPR_MLP1_2 PF07926.12 KFQ98654.1 - 7.4 6.6 8.5 5.9 7.0 1.1 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Snf7 PF03357.21 KFQ98655.1 - 2.2e-35 121.8 15.2 2.7e-35 121.5 15.2 1.0 1 0 0 1 1 1 1 Snf7 IMD PF08397.11 KFQ98656.1 - 1.3e-95 319.0 6.9 1.8e-95 318.5 6.9 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain SH3_9 PF14604.6 KFQ98656.1 - 3e-10 39.8 0.0 5.4e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFQ98656.1 - 1.2e-07 31.3 0.0 2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFQ98656.1 - 3.6e-05 23.3 0.0 6.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain BAR PF03114.18 KFQ98656.1 - 0.00025 20.8 5.4 0.0004 20.1 5.4 1.4 1 0 0 1 1 1 1 BAR domain Peptidase_Mx1 PF15890.5 KFQ98656.1 - 0.013 14.9 0.8 0.022 14.2 0.8 1.3 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase BAR_3 PF16746.5 KFQ98656.1 - 0.099 12.3 11.4 0.19 11.4 11.4 1.5 1 1 0 1 1 1 0 BAR domain of APPL family DUF445 PF04286.12 KFQ98656.1 - 0.17 11.6 1.4 0.24 11.2 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) AAA_lid_9 PF17871.1 KFQ98656.1 - 0.99 9.4 4.2 20 5.2 0.0 2.8 2 1 1 3 3 3 0 AAA lid domain RasGAP PF00616.19 KFQ98656.1 - 1.2 8.8 8.5 3.6 7.2 8.9 1.6 1 1 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase Exonuc_VII_L PF02601.15 KFQ98656.1 - 2.4 7.6 6.6 3.5 7.1 6.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.14 KFQ98656.1 - 2.7 8.3 14.1 1.2 9.5 7.9 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) IQ PF00612.27 KFQ98658.1 - 0.0071 16.1 1.3 0.036 13.8 1.3 2.3 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF2284 PF10050.9 KFQ98658.1 - 0.89 9.3 3.6 10 5.8 3.6 2.9 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) ENTH PF01417.20 KFQ98659.1 - 0.017 15.2 0.0 0.042 13.9 0.0 1.6 2 0 0 2 2 2 0 ENTH domain HEAT_EZ PF13513.6 KFQ98659.1 - 0.1 13.1 0.9 0.33 11.5 0.1 2.2 2 0 0 2 2 2 0 HEAT-like repeat Actin PF00022.19 KFQ98661.1 - 4.2e-149 496.6 0.0 1.4e-148 494.9 0.0 1.7 1 1 0 1 1 1 1 Actin Fascin PF06268.13 KFQ98663.1 - 3.7e-95 313.7 0.3 1.3e-30 105.9 0.1 4.0 4 0 0 4 4 4 4 Fascin domain FRG1 PF06229.12 KFQ98663.1 - 5.3e-22 78.5 0.0 2.8e-05 23.9 0.0 5.6 3 1 3 6 6 6 5 FRG1-like domain FGF PF00167.18 KFQ98663.1 - 0.00013 22.0 0.0 1.1 9.4 0.0 4.1 3 1 0 4 4 4 1 Fibroblast growth factor FANCAA PF15146.6 KFQ98664.1 - 3.3e-45 155.0 0.5 3.6e-45 154.8 0.5 1.0 1 0 0 1 1 1 1 Fanconi anemia-associated FANCAA PF15146.6 KFQ98665.1 - 9.2e-128 427.0 0.9 1e-127 426.9 0.9 1.0 1 0 0 1 1 1 1 Fanconi anemia-associated NPL4 PF05021.15 KFQ98666.1 - 7.1e-97 324.5 0.0 1.1e-96 323.8 0.0 1.3 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KFQ98666.1 - 2.6e-62 209.3 0.2 4.3e-62 208.5 0.2 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 KFQ98666.1 - 8.8e-31 106.2 0.1 1.6e-30 105.4 0.1 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 PDE6_gamma PF04868.12 KFQ98667.1 - 9.1e-49 163.6 0.6 1e-48 163.5 0.6 1.0 1 0 0 1 1 1 1 Retinal cGMP phosphodiesterase, gamma subunit TAL_effector PF03377.13 KFQ98668.1 - 0.022 15.1 0.2 0.031 14.6 0.2 1.3 1 0 0 1 1 1 0 TAL effector repeat 7tm_1 PF00001.21 KFQ98670.1 - 8.5e-24 84.3 21.7 1e-23 84.0 21.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFQ98670.1 - 2.3e-08 33.7 16.4 7.7e-07 28.7 5.0 2.2 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 KFQ98670.1 - 1.4e-07 31.4 8.4 1.4e-07 31.4 8.4 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4407 PF14362.6 KFQ98670.1 - 1.1 8.6 5.4 1.8 7.8 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BACK PF07707.15 KFQ98671.1 - 7.7e-17 61.3 0.5 5.5e-16 58.5 0.0 2.6 4 0 0 4 4 4 1 BTB And C-terminal Kelch BTB PF00651.31 KFQ98671.1 - 2.7e-10 40.5 0.1 8.1e-10 38.9 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Kinesin PF00225.23 KFQ98672.1 - 1.4e-106 356.2 0.2 1.8e-106 355.9 0.2 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFQ98672.1 - 1.7e-21 76.7 0.0 3.1e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding WD40 PF00400.32 KFQ98673.1 - 0.012 16.4 8.4 0.052 14.4 0.0 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat HlyE PF06109.13 KFQ98673.1 - 0.17 11.1 0.1 0.27 10.5 0.1 1.2 1 0 0 1 1 1 0 Haemolysin E (HlyE) Tweety PF04906.13 KFQ98674.1 - 8.1e-124 413.4 5.1 9.2e-124 413.2 5.1 1.0 1 0 0 1 1 1 1 Tweety PAP2_3 PF14378.6 KFQ98674.1 - 0.0068 16.1 1.0 0.059 13.0 1.4 2.0 2 0 0 2 2 2 1 PAP2 superfamily Glucos_trans_II PF14264.6 KFQ98674.1 - 0.013 14.9 2.1 0.013 14.9 2.1 1.6 2 0 0 2 2 2 0 Glucosyl transferase GtrII Tetraspanin PF00335.20 KFQ98674.1 - 0.2 11.3 12.5 0.028 14.1 8.3 1.7 1 1 0 1 1 1 0 Tetraspanin family Ribosomal_L38e PF01781.18 KFQ98675.1 - 1.1e-35 121.6 4.7 1.2e-35 121.5 4.7 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family fn3 PF00041.21 KFQ98676.1 - 7.2e-178 577.5 29.1 8.6e-16 58.1 0.2 14.4 14 1 0 14 14 14 13 Fibronectin type III domain I-set PF07679.16 KFQ98676.1 - 1.1e-64 214.5 0.0 8.6e-15 54.6 0.0 7.8 7 0 0 7 7 7 6 Immunoglobulin I-set domain Ig_3 PF13927.6 KFQ98676.1 - 1.8e-64 214.3 0.0 1.2e-12 48.3 0.0 7.2 6 0 0 6 6 6 6 Immunoglobulin domain Ig_2 PF13895.6 KFQ98676.1 - 8.6e-47 157.4 0.0 1.8e-09 37.8 0.0 6.5 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.25 KFQ98676.1 - 4.8e-31 106.8 0.0 3.7e-09 36.6 0.0 7.1 6 1 0 6 6 6 5 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFQ98676.1 - 4.3e-26 91.3 16.6 0.011 16.3 0.0 14.0 13 2 0 13 13 13 6 Purple acid Phosphatase, N-terminal domain V-set PF07686.17 KFQ98676.1 - 3.3e-20 72.3 2.1 0.0012 19.0 0.0 9.6 6 5 1 7 7 7 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFQ98676.1 - 5.9e-09 35.9 0.0 1.5 8.9 0.0 5.5 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFQ98676.1 - 4.1e-08 33.5 0.0 0.3 11.5 0.0 5.6 5 1 0 5 5 5 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Interfer-bind PF09294.10 KFQ98676.1 - 5e-08 33.2 0.0 2.2 8.6 0.0 6.8 6 0 0 6 6 6 1 Interferon-alpha/beta receptor, fibronectin type III Ig_6 PF18452.1 KFQ98676.1 - 1.4e-06 27.8 0.0 1.2 8.7 0.0 5.6 5 0 0 5 5 5 1 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFQ98676.1 - 0.00048 20.1 0.0 6.8 6.8 0.0 4.5 5 0 0 5 5 4 1 C17orf99 Ig domain GPI-anchored PF10342.9 KFQ98676.1 - 0.0074 17.0 8.4 2.4 9.0 0.0 7.8 9 1 1 10 10 10 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family C1-set PF07654.15 KFQ98676.1 - 0.076 13.4 0.1 7.2 7.1 0.0 3.8 4 1 0 4 4 3 0 Immunoglobulin C1-set domain Y_Y_Y PF07495.13 KFQ98676.1 - 1.2 9.1 2.9 8 6.5 0.0 3.7 5 0 0 5 5 4 0 Y_Y_Y domain BORG_CEP PF14957.6 KFQ98677.1 - 1.4e-22 81.1 0.4 4.2e-22 79.6 0.4 1.8 1 0 0 1 1 1 1 Cdc42 effector PBD PF00786.28 KFQ98677.1 - 1.1e-08 35.3 0.0 3.4e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain zf-CCCH PF00642.24 KFQ98678.1 - 9.4e-18 63.7 34.2 9.3e-05 22.2 0.6 6.1 5 1 1 6 6 6 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFQ98678.1 - 1.3e-13 50.5 44.8 2.7e-05 24.1 3.5 7.0 6 1 0 6 6 6 5 Zinc finger domain Torus PF16131.5 KFQ98678.1 - 5.7e-09 36.6 29.9 0.001 19.7 0.7 5.1 1 1 4 5 5 5 4 Torus domain zf-CCCH_4 PF18044.1 KFQ98678.1 - 3.7e-06 26.6 7.9 2.2e-05 24.2 0.9 5.7 5 1 0 5 5 5 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KFQ98678.1 - 0.00064 19.9 23.4 0.00089 19.4 11.8 3.2 1 1 2 3 3 3 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 KFQ98678.1 - 0.002 18.5 39.1 0.52 10.9 1.1 6.3 5 2 0 5 5 5 4 RNA-binding, Nab2-type zinc finger WRW PF10206.9 KFQ98679.1 - 4.4e-11 43.0 0.0 5.4e-11 42.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f F1F0-ATPsyn_F PF10791.9 KFQ98679.1 - 0.12 12.9 0.1 0.15 12.6 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi FAM104 PF15434.6 KFQ98680.1 - 1.6e-49 167.0 8.6 2.1e-49 166.6 8.6 1.2 1 0 0 1 1 1 1 Family 104 SR-25 PF10500.9 KFQ98680.1 - 7.3 6.1 22.1 0.84 9.2 18.2 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3510 PF12022.8 KFQ98681.1 - 0.012 16.0 0.0 0.056 13.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) 7tm_1 PF00001.21 KFQ98682.1 - 1.6e-65 221.1 19.8 1.9e-65 220.8 19.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ98682.1 - 1.2e-16 60.9 21.2 1.5e-16 60.6 21.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFQ98682.1 - 2.3e-14 53.7 12.3 2.3e-14 53.7 12.3 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFQ98682.1 - 1.5e-11 44.2 8.2 1.5e-11 44.2 8.2 2.1 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv EVC2_like PF12297.8 KFQ98682.1 - 0.39 9.4 0.7 0.57 8.8 0.7 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein FA_desaturase PF00487.24 KFQ98682.1 - 5 6.9 9.4 1.5 8.6 1.4 2.7 1 1 1 2 2 2 0 Fatty acid desaturase Zip PF02535.22 KFQ98683.1 - 5.7e-25 88.2 10.8 1.5e-24 86.8 10.8 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter HMG_box PF00505.19 KFQ98684.1 - 6.7e-26 90.5 1.3 1.6e-25 89.3 1.3 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box Sox_N PF12444.8 KFQ98684.1 - 1.6e-19 70.8 0.1 1.6e-19 70.8 0.1 3.8 4 1 0 4 4 4 1 Sox developmental protein N terminal HMG_box_2 PF09011.10 KFQ98684.1 - 7.6e-11 42.4 1.1 1.9e-10 41.1 1.1 1.7 1 0 0 1 1 1 1 HMG-box domain VIT_2 PF13757.6 KFQ98684.1 - 0.052 13.5 0.4 0.098 12.6 0.4 1.4 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain IRK_C PF17655.1 KFQ98686.1 - 2.9e-77 258.2 0.0 4.3e-77 257.6 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFQ98686.1 - 1.8e-64 215.8 6.2 2.6e-64 215.3 6.2 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain IRK_N PF08466.10 KFQ98686.1 - 1.7e-26 92.1 1.3 3.5e-26 91.1 1.3 1.6 1 0 0 1 1 1 1 Inward rectifier potassium channel N-terminal Ion_trans_2 PF07885.16 KFQ98686.1 - 0.0011 18.8 6.4 0.0027 17.6 6.4 1.7 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.31 KFQ98686.1 - 0.0033 16.7 5.4 0.0047 16.2 5.4 1.2 1 0 0 1 1 1 1 Ion transport protein IRK_C PF17655.1 KFQ98687.1 - 2.8e-62 209.4 0.0 4.1e-62 208.9 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFQ98687.1 - 4e-57 192.0 7.4 6.1e-57 191.4 7.4 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 KFQ98687.1 - 0.0034 17.3 6.5 0.008 16.1 6.4 1.8 1 1 0 1 1 1 1 Ion channel Pkinase PF00069.25 KFQ98688.1 - 4e-46 157.5 0.0 4.4e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ98688.1 - 4.9e-31 107.9 0.0 5.8e-31 107.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFQ98688.1 - 0.0011 18.0 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFQ98688.1 - 0.0017 17.7 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KFQ98688.1 - 0.0031 16.6 0.2 0.0045 16.1 0.2 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 KFQ98688.1 - 0.0035 16.2 0.1 0.0083 14.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFQ98688.1 - 0.01 15.8 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFQ98688.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase CLP1_P PF16575.5 KFQ98688.1 - 0.043 13.6 0.1 0.089 12.6 0.1 1.5 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF4344 PF14247.6 KFQ98688.1 - 0.071 12.8 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase PIP49_C PF12260.8 KFQ98688.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 ABC_tran PF00005.27 KFQ98689.1 - 2.7e-59 199.6 0.0 6.1e-29 101.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KFQ98689.1 - 2.1e-43 148.8 52.7 1.4e-28 100.1 20.7 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KFQ98689.1 - 1.2e-15 58.2 0.0 0.00041 20.3 0.0 4.6 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFQ98689.1 - 2.1e-10 40.8 0.1 0.00082 19.3 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KFQ98689.1 - 1.7e-06 27.6 0.5 0.085 12.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KFQ98689.1 - 3e-06 27.7 0.0 0.092 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KFQ98689.1 - 1.2e-05 25.4 0.1 0.11 12.6 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_23 PF13476.6 KFQ98689.1 - 6.1e-05 23.6 8.9 0.056 13.9 0.2 3.3 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KFQ98689.1 - 0.00022 21.5 0.7 1.4 9.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KFQ98689.1 - 0.00051 19.9 0.2 1.8 8.2 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.22 KFQ98689.1 - 0.00095 18.4 0.8 4.3 6.4 0.0 3.2 3 0 0 3 3 3 1 NB-ARC domain SMC_N PF02463.19 KFQ98689.1 - 0.0015 18.0 0.1 4.7 6.6 0.0 3.8 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KFQ98689.1 - 0.003 17.3 0.1 1.9 8.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KFQ98689.1 - 0.0044 16.6 1.2 0.43 10.2 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 KFQ98689.1 - 0.0045 17.1 0.0 0.095 12.8 0.0 2.7 2 1 0 2 2 2 1 Dynamin family AAA_5 PF07728.14 KFQ98689.1 - 0.0046 17.0 0.7 2.1 8.3 0.0 4.1 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KFQ98689.1 - 0.0048 17.3 0.1 2.9 8.3 0.0 2.8 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 KFQ98689.1 - 0.0061 16.3 0.0 2 8.2 0.0 3.4 4 0 0 4 4 3 1 IstB-like ATP binding protein AAA PF00004.29 KFQ98689.1 - 0.0068 16.8 0.0 3.8 7.9 0.0 3.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KFQ98689.1 - 0.0084 16.3 0.1 7.7 6.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 KFQ98689.1 - 0.0097 15.8 0.1 0.35 10.8 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain NACHT PF05729.12 KFQ98689.1 - 0.016 15.1 0.3 12 5.8 0.2 3.2 3 0 0 3 3 3 0 NACHT domain AAA_24 PF13479.6 KFQ98689.1 - 0.021 14.5 0.1 4.6 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KFQ98689.1 - 0.021 14.8 0.7 9.1 6.3 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF4162 PF13732.6 KFQ98689.1 - 0.024 15.4 0.4 1.7 9.4 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_7 PF12775.7 KFQ98689.1 - 0.04 13.4 0.3 5.5 6.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 KFQ98689.1 - 0.047 13.3 0.1 4.6 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 KFQ98689.1 - 0.082 12.8 0.2 6.5 6.7 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B T2SSE PF00437.20 KFQ98689.1 - 0.09 11.8 0.1 3.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Pox_vIL-18BP PF05566.12 KFQ98689.1 - 0.1 12.8 0.0 0.35 11.1 0.0 1.9 1 0 0 1 1 1 0 Orthopoxvirus interleukin 18 binding protein Roc PF08477.13 KFQ98689.1 - 0.12 12.6 0.3 25 5.1 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Pullulanase_Ins PF18494.1 KFQ98689.1 - 0.14 12.6 0.1 0.58 10.7 0.1 2.0 1 0 0 1 1 1 0 Pullulanase Ins domain Septin PF00735.18 KFQ98689.1 - 0.17 11.1 0.8 9 5.5 0.0 2.9 3 0 0 3 3 3 0 Septin ATP-synt_ab PF00006.25 KFQ98689.1 - 0.21 11.2 0.0 2.2 7.9 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Mg_chelatase PF01078.21 KFQ98689.1 - 0.21 10.9 0.3 13 5.0 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI FeoB_N PF02421.18 KFQ98689.1 - 0.22 11.0 0.7 7.8 6.0 0.1 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_28 PF13521.6 KFQ98689.1 - 0.72 10.1 1.8 26 5.0 0.2 2.4 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 KFQ98689.1 - 0.75 8.9 3.2 20 4.2 0.0 3.2 3 0 0 3 3 3 0 PIF1-like helicase ABC2_membrane_3 PF12698.7 KFQ98690.1 - 3.5e-09 36.2 2.5 4.2e-09 36.0 2.5 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF898 PF05987.13 KFQ98690.1 - 0.011 14.8 0.6 0.013 14.6 0.6 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) ABC2_membrane_3 PF12698.7 KFQ98691.1 - 1.1e-07 31.3 7.1 1.4e-07 31.0 7.1 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 KFQ98691.1 - 0.00011 22.8 0.1 0.00015 22.3 0.1 1.2 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KFQ98691.1 - 0.042 13.7 0.0 0.058 13.3 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KFQ98691.1 - 0.048 13.4 0.1 0.09 12.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KFQ98693.1 - 4.9e-13 49.8 0.0 8.3e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFQ98693.1 - 0.0018 18.2 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 KFQ98694.1 - 2.8e-62 209.3 0.1 9.6e-31 107.1 0.4 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KFQ98694.1 - 1.1e-34 120.1 47.4 5.2e-25 88.3 26.8 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KFQ98694.1 - 3.9e-16 59.7 3.2 9.4e-07 28.9 0.0 4.7 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFQ98694.1 - 6.9e-10 39.1 3.6 0.00018 21.5 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KFQ98694.1 - 8.8e-06 25.4 2.3 0.013 15.2 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KFQ98694.1 - 0.00013 22.5 6.4 0.044 14.3 0.8 2.8 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 KFQ98694.1 - 0.00023 20.7 0.7 0.65 9.4 0.1 3.8 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KFQ98694.1 - 0.00024 21.2 0.6 0.36 10.9 0.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase Rad17 PF03215.15 KFQ98694.1 - 0.00067 19.6 0.4 0.85 9.5 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_30 PF13604.6 KFQ98694.1 - 0.0038 17.0 0.6 2.5 7.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KFQ98694.1 - 0.0088 15.8 0.3 5.1 6.8 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_22 PF13401.6 KFQ98694.1 - 0.011 16.0 1.6 0.96 9.7 0.2 2.9 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KFQ98694.1 - 0.011 16.1 0.3 0.64 10.4 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 KFQ98694.1 - 0.022 14.8 0.2 5.7 7.0 0.0 3.0 2 1 0 2 2 2 0 Dynamin family AAA_15 PF13175.6 KFQ98694.1 - 0.062 13.0 4.9 15 5.2 0.8 3.8 3 1 0 3 3 3 0 AAA ATPase domain AAA_24 PF13479.6 KFQ98694.1 - 0.075 12.8 0.4 15 5.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KFQ98694.1 - 0.088 12.4 0.8 3.3 7.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KFQ98694.1 - 0.13 12.5 0.8 17 5.6 0.2 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KFQ98694.1 - 0.16 11.6 2.2 2.2 7.8 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 KFQ98694.1 - 0.2 12.1 2.1 6.9 7.1 0.2 3.3 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KFQ98694.1 - 0.42 10.6 4.0 8.9 6.3 0.2 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 KFQ98694.1 - 0.66 10.4 3.6 16 5.9 0.2 3.2 4 0 0 4 4 3 0 AAA domain Fam20C PF06702.12 KFQ98695.1 - 1.6e-97 325.6 0.0 2.1e-97 325.2 0.0 1.1 1 0 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 FAM198 PF15051.6 KFQ98695.1 - 0.0054 15.7 0.3 0.011 14.7 0.0 1.6 2 0 0 2 2 2 1 FAM198 protein PI3_PI4_kinase PF00454.27 KFQ98695.1 - 0.14 12.0 0.7 0.26 11.1 0.7 1.4 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase cNMP_binding PF00027.29 KFQ98696.1 - 5.8e-39 132.1 0.1 2.4e-19 69.2 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 KFQ98696.1 - 2.9e-14 52.5 0.1 5.9e-14 51.4 0.1 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Cupin_2 PF07883.11 KFQ98696.1 - 0.029 14.1 1.6 1.5 8.6 0.1 2.3 2 0 0 2 2 2 0 Cupin domain Cupin_3 PF05899.12 KFQ98696.1 - 0.71 9.6 2.6 18 5.1 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF861) WD40 PF00400.32 KFQ98697.1 - 0.00078 20.2 0.0 16 6.6 0.0 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ98697.1 - 0.004 17.4 0.0 0.87 9.9 0.0 3.7 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain BCAS3 PF12490.8 KFQ98697.1 - 0.025 14.1 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 Sulfatase PF00884.23 KFQ98698.1 - 1.5e-70 238.0 0.0 1.9e-70 237.7 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KFQ98698.1 - 3.8e-23 82.6 0.0 6.8e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 KFQ98698.1 - 0.0047 16.6 0.0 0.0094 15.6 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.16 KFQ98699.1 - 1.9e-37 129.0 20.5 8.1e-36 123.7 15.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily G-alpha PF00503.20 KFQ98700.1 - 1.5e-85 287.5 1.4 1.6e-85 287.4 1.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFQ98700.1 - 2.1e-14 53.4 1.0 3.1e-13 49.5 0.2 2.3 2 1 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFQ98700.1 - 0.0011 18.4 0.3 0.0017 17.7 0.3 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RGS_DHEX PF18148.1 KFQ98701.1 - 5.5e-45 151.5 2.7 1.2e-44 150.5 2.7 1.6 1 0 0 1 1 1 1 Regulator of G-protein signalling DHEX domain RGS PF00615.19 KFQ98701.1 - 2.1e-32 111.8 0.0 4e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 KFQ98701.1 - 4e-13 49.2 0.0 1.1e-12 47.8 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.22 KFQ98701.1 - 9.2e-09 35.2 0.0 4.6e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 GGL domain MNR PF15718.5 KFQ98701.1 - 0.19 9.8 0.1 0.27 9.3 0.1 1.1 1 0 0 1 1 1 0 Protein moonraker DUF424 PF04242.13 KFQ98702.1 - 0.21 11.9 4.3 1.6 9.1 0.7 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF424) Sushi PF00084.20 KFQ98703.1 - 7.3e-41 138.6 21.3 5.1e-11 43.0 0.6 5.0 5 0 0 5 5 5 4 Sushi repeat (SCR repeat) Sushi_2 PF09014.10 KFQ98703.1 - 5.9e-28 96.6 1.2 5.9e-28 96.6 1.2 2.3 4 0 0 4 4 4 1 Beta-2-glycoprotein-1 fifth domain HRM PF02793.22 KFQ98703.1 - 0.00053 20.2 12.5 1.7 9.0 0.1 4.5 4 0 0 4 4 4 2 Hormone receptor domain YTV PF07639.11 KFQ98703.1 - 0.1 12.7 1.8 1.4 9.1 0.2 2.7 2 0 0 2 2 2 0 YTV Meleagrin PF08189.11 KFQ98703.1 - 0.81 9.4 14.0 1.3 8.8 2.1 4.0 4 0 0 4 4 4 0 Meleagrin/Cygnin family cEGF PF12662.7 KFQ98703.1 - 6.3 6.8 11.3 5.7 7.0 0.4 3.4 3 0 0 3 3 3 0 Complement Clr-like EGF-like Pkinase PF00069.25 KFQ98704.1 - 4e-64 216.5 0.0 5.4e-64 216.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ98704.1 - 1.1e-37 129.8 0.0 1.5e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 KFQ98704.1 - 2.1e-29 101.8 0.1 3.5e-29 101.1 0.1 1.3 1 0 0 1 1 1 1 C2 domain C1_1 PF00130.22 KFQ98704.1 - 4.9e-18 64.7 15.9 2e-16 59.6 4.8 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KFQ98704.1 - 0.00033 21.3 0.6 0.0009 19.9 0.6 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KFQ98704.1 - 0.044 12.7 0.1 0.067 12.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KFQ98704.1 - 0.12 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KFQ98704.1 - 0.19 11.0 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like PMP22_Claudin PF00822.20 KFQ98705.1 - 1.4e-24 86.8 0.0 2.6e-24 86.0 0.0 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFQ98705.1 - 3.5e-10 39.9 0.0 5.4e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction AA_permease_2 PF13520.6 KFQ98705.1 - 0.003 16.4 0.0 0.0041 16.0 0.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4195 PF13836.6 KFQ98705.1 - 0.01 16.0 1.4 0.015 15.4 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4195) DUF2269 PF10027.9 KFQ98705.1 - 0.015 15.3 0.0 0.025 14.6 0.0 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) DUF4199 PF13858.6 KFQ98705.1 - 0.024 15.0 0.0 0.033 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Claudin_2 PF13903.6 KFQ98706.1 - 3.4e-39 134.6 5.2 4.3e-39 134.3 5.2 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFQ98706.1 - 3.4e-15 56.3 11.5 1.4e-08 34.8 7.2 2.1 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.11 KFQ98706.1 - 0.038 13.9 6.9 0.72 9.8 4.5 2.1 2 0 0 2 2 2 0 Tight junction protein, Claudin-like DUF981 PF06168.11 KFQ98706.1 - 0.048 13.6 3.1 0.15 12.0 1.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF981) DUF2207 PF09972.9 KFQ98706.1 - 0.17 10.7 0.6 0.26 10.0 0.2 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) PDR_assoc PF08370.11 KFQ98706.1 - 0.17 11.6 2.3 17 5.2 0.0 2.8 3 0 0 3 3 3 0 Plant PDR ABC transporter associated DuoxA PF10204.9 KFQ98706.1 - 0.27 10.2 5.6 0.076 12.0 2.5 1.6 2 0 0 2 2 2 0 Dual oxidase maturation factor DUF805 PF05656.14 KFQ98706.1 - 0.48 10.9 3.4 0.23 11.9 1.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF805) UNC-50 PF05216.13 KFQ98706.1 - 0.84 9.2 8.5 0.041 13.4 3.3 1.4 2 0 0 2 2 2 0 UNC-50 family AAA_12 PF13087.6 KFQ98707.1 - 1.3e-34 119.6 0.0 2.7e-34 118.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFQ98707.1 - 8.7e-23 81.4 11.0 2.2e-12 47.3 0.1 3.8 3 1 1 4 4 4 2 AAA domain AAA_19 PF13245.6 KFQ98707.1 - 5.1e-10 39.9 0.0 6.8e-08 33.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFQ98707.1 - 8.4e-09 35.4 0.0 3.8e-08 33.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain zf-CCCH PF00642.24 KFQ98707.1 - 7.3e-08 32.1 0.6 2e-07 30.8 0.6 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ResIII PF04851.15 KFQ98707.1 - 1.7e-05 24.9 0.0 4.1e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KFQ98707.1 - 2.4e-05 23.9 0.0 0.02 14.4 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein UvrD-helicase PF00580.21 KFQ98707.1 - 0.00011 21.9 0.0 0.00011 21.9 0.0 2.8 4 0 0 4 4 4 1 UvrD/REP helicase N-terminal domain PAM2 PF07145.15 KFQ98707.1 - 0.00022 20.7 0.1 0.00092 18.7 0.1 2.2 1 0 0 1 1 1 1 Ataxin-2 C-terminal region zf_CCCH_4 PF18345.1 KFQ98707.1 - 0.0011 18.9 1.2 0.0029 17.6 1.2 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KFQ98707.1 - 0.0055 16.5 0.3 0.014 15.2 0.3 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger AAA_7 PF12775.7 KFQ98707.1 - 0.024 14.2 0.0 0.072 12.6 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Helicase_RecD PF05127.14 KFQ98707.1 - 0.039 13.8 0.1 0.24 11.2 0.0 2.4 2 0 0 2 2 2 0 Helicase AAA_14 PF13173.6 KFQ98707.1 - 0.04 14.0 0.0 1.8 8.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KFQ98707.1 - 0.045 14.0 0.0 0.18 12.1 0.0 2.2 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 KFQ98707.1 - 0.071 12.9 0.3 0.31 10.8 0.0 2.1 3 0 0 3 3 3 0 Bacterial dnaA protein AAA_16 PF13191.6 KFQ98707.1 - 0.087 13.2 0.0 0.5 10.7 0.0 2.3 2 0 0 2 2 1 0 AAA ATPase domain AAA_5 PF07728.14 KFQ98707.1 - 0.17 11.9 0.1 0.63 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PCI PF01399.27 KFQ98708.1 - 3.7e-23 82.0 2.2 1e-22 80.6 0.1 2.8 2 1 0 2 2 2 1 PCI domain RPN5_C PF18098.1 KFQ98708.1 - 1.9e-15 56.6 8.4 4.4e-15 55.5 8.4 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain Hydrophob_seed PF14547.6 KFQ98708.1 - 0.082 13.1 0.1 0.22 11.8 0.1 1.7 1 0 0 1 1 1 0 Hydrophobic seed protein Tubulin_C PF03953.17 KFQ98708.1 - 0.16 12.2 0.6 0.7 10.1 0.1 2.4 2 1 1 3 3 3 0 Tubulin C-terminal domain Retrotrans_gag PF03732.17 KFQ98708.1 - 0.3 11.4 1.7 20 5.5 0.0 3.7 3 1 1 4 4 4 0 Retrotransposon gag protein Symplekin_C PF12295.8 KFQ98708.1 - 1.8 8.6 8.3 1.4 9.0 0.6 2.9 2 1 1 3 3 3 0 Symplekin tight junction protein C terminal IP_trans PF02121.18 KFQ98709.1 - 1.5e-93 312.9 3.7 1.8e-93 312.7 3.7 1.1 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein NUC205 PF08168.11 KFQ98710.1 - 1.4e-07 30.9 0.1 3.2e-07 29.7 0.1 1.7 1 0 0 1 1 1 1 NUC205 domain HisG_C PF08029.11 KFQ98710.1 - 0.015 15.4 0.0 0.63 10.2 0.0 2.5 2 0 0 2 2 2 0 HisG, C-terminal domain UTP15_C PF09384.10 KFQ98710.1 - 0.058 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 UTP15 C terminal Bromodomain PF00439.25 KFQ98711.1 - 9.1e-26 89.8 0.2 2.2e-25 88.5 0.2 1.7 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 KFQ98711.1 - 5e-18 64.7 28.7 2e-09 37.2 7.1 3.1 2 0 0 2 2 2 2 PHD-finger DDT PF02791.17 KFQ98711.1 - 4.8e-17 62.0 0.3 9.9e-17 61.0 0.3 1.6 1 0 0 1 1 1 1 DDT domain WSD PF15613.6 KFQ98711.1 - 9e-10 38.9 1.5 9e-10 38.9 1.5 6.1 6 1 0 6 6 6 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 KFQ98711.1 - 0.00023 20.6 0.0 0.00069 19.1 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 HK97-gp10_like PF04883.12 KFQ98711.1 - 1.3 10.0 5.1 1.6 9.8 1.2 3.0 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component C1_1 PF00130.22 KFQ98711.1 - 1.7 8.6 14.3 4.8 7.1 1.2 2.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Arc_PepC_II PF06847.11 KFQ98711.1 - 9.1 6.9 6.3 2.1 8.9 0.4 3.1 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II NTR PF01759.21 KFQ98712.1 - 0.07 12.9 0.0 0.079 12.8 0.0 1.3 1 1 0 1 1 1 0 UNC-6/NTR/C345C module Ribosomal_L35p PF01632.19 KFQ98712.1 - 0.079 13.5 0.6 0.14 12.7 0.6 1.4 1 0 0 1 1 1 0 Ribosomal protein L35 Arm PF00514.23 KFQ98714.1 - 1.3e-81 266.5 4.0 8.9e-11 41.4 0.0 8.6 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KFQ98714.1 - 2.9e-30 104.5 6.7 8.8e-30 103.0 6.7 1.9 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 KFQ98714.1 - 1.1e-24 85.7 2.8 2.1e-24 84.8 2.1 1.8 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 KFQ98714.1 - 1.6e-19 70.0 0.1 2.9e-06 27.7 0.0 5.7 4 1 1 5 5 5 3 HEAT-like repeat HEAT_2 PF13646.6 KFQ98714.1 - 2e-11 44.1 0.0 0.0088 16.4 0.0 5.4 3 2 2 6 6 6 3 HEAT repeats HEAT PF02985.22 KFQ98714.1 - 3.8e-08 32.9 0.9 0.15 12.4 0.0 6.5 7 0 0 7 7 7 2 HEAT repeat UxaC PF02614.14 KFQ98714.1 - 0.029 13.2 0.0 3.2 6.5 0.0 2.3 2 0 0 2 2 2 0 Glucuronate isomerase SYCP2_ARLD PF18581.1 KFQ98714.1 - 0.06 13.3 0.2 32 4.5 0.0 3.7 3 1 0 4 4 4 0 Synaptonemal complex 2 armadillo-repeat-like domain ECF-ribofla_trS PF07155.12 KFQ98714.1 - 0.12 12.3 0.1 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component HECT PF00632.25 KFQ98715.1 - 1.9e-102 342.9 0.0 2.5e-102 342.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KFQ98715.1 - 5.6e-30 103.1 9.4 2.4e-11 43.5 0.2 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.30 KFQ98715.1 - 5e-15 55.7 0.0 1.2e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain HPS3_N PF14761.6 KFQ98715.1 - 0.051 13.1 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 DEAD PF00270.29 KFQ98716.1 - 1.1e-48 165.4 0.0 7.6e-48 162.6 0.0 2.3 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFQ98716.1 - 2.6e-31 108.2 0.0 1e-30 106.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain P68HR PF08061.11 KFQ98716.1 - 5.2e-28 96.9 21.0 3.2e-14 52.7 4.6 2.6 2 0 0 2 2 2 2 P68HR (NUC004) repeat ResIII PF04851.15 KFQ98716.1 - 0.0001 22.4 0.0 0.00099 19.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFQ98716.1 - 0.0074 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HGTP_anticodon PF03129.20 KFQ98717.1 - 2.1e-11 43.8 0.0 3.5e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain Ig_C17orf99 PF17736.1 KFQ98718.1 - 1.3e-22 79.7 2.4 4.6e-11 42.6 0.1 2.2 2 0 0 2 2 2 2 C17orf99 Ig domain Ig_3 PF13927.6 KFQ98718.1 - 1.4e-22 80.1 0.5 4.4e-10 40.0 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFQ98718.1 - 1.3e-17 63.9 2.8 2.5e-08 34.1 0.2 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFQ98718.1 - 6e-13 48.8 2.4 1e-06 28.8 0.2 2.5 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFQ98718.1 - 1.1e-09 38.2 0.0 0.0019 18.2 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 KFQ98718.1 - 7.2e-06 26.1 5.6 4.2 7.6 0.1 4.1 2 2 2 4 4 4 3 Immunoglobulin V-set domain Ig_C19orf38 PF17737.1 KFQ98718.1 - 5.5e-05 23.4 0.1 0.051 13.9 0.0 2.3 2 0 0 2 2 2 2 Ig domain in C19orf38 (HIDE1) C2-set_2 PF08205.12 KFQ98718.1 - 0.00082 19.4 0.0 0.21 11.7 0.0 2.2 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 KFQ98719.1 - 3.2e-43 145.9 3.7 1.3e-08 35.0 0.1 6.2 6 0 0 6 6 6 6 Immunoglobulin domain Ig_3 PF13927.6 KFQ98719.1 - 1.3e-35 121.8 0.7 2.5e-05 24.8 0.0 6.9 7 0 0 7 7 7 6 Immunoglobulin domain ig PF00047.25 KFQ98719.1 - 3.2e-21 75.3 9.1 2.5e-05 24.4 0.0 8.2 6 3 0 6 6 6 5 Immunoglobulin domain I-set PF07679.16 KFQ98719.1 - 6e-15 55.1 12.6 0.06 13.4 0.1 7.7 6 3 0 6 6 6 5 Immunoglobulin I-set domain V-set PF07686.17 KFQ98719.1 - 1.2e-12 47.9 6.6 0.15 12.2 0.1 7.8 6 3 1 7 7 7 4 Immunoglobulin V-set domain Ig_C17orf99 PF17736.1 KFQ98719.1 - 2.1e-11 43.7 0.0 0.0093 16.0 0.0 5.3 6 0 0 6 6 6 2 C17orf99 Ig domain Ig_6 PF18452.1 KFQ98719.1 - 9.1e-08 31.6 0.2 0.57 9.8 0.0 4.9 5 0 0 5 5 5 3 Immunoglobulin domain Izumo-Ig PF16706.5 KFQ98719.1 - 1.1e-07 31.8 2.5 0.1 12.7 0.1 5.5 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFQ98719.1 - 0.0002 21.7 3.1 0.046 14.1 0.0 4.6 5 0 0 5 5 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_Tie2_1 PF10430.9 KFQ98719.1 - 0.015 15.7 0.5 0.25 11.8 0.1 2.9 3 0 0 3 3 3 0 Tie-2 Ig-like domain 1 ICAM_N PF03921.14 KFQ98719.1 - 0.019 14.6 2.6 0.75 9.5 0.1 3.0 2 0 0 2 2 2 0 Intercellular adhesion molecule (ICAM), N-terminal domain C2-set PF05790.15 KFQ98719.1 - 0.042 14.0 1.1 20 5.4 0.0 4.9 4 2 0 4 4 4 0 Immunoglobulin C2-set domain DUF3108 PF11306.8 KFQ98719.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3108) MMM1 PF10296.9 KFQ98720.1 - 0.0014 17.8 4.3 0.0014 17.7 0.0 2.9 3 0 0 3 3 3 1 Maintenance of mitochondrial morphology protein 1 Pkinase PF00069.25 KFQ98721.1 - 1.3e-44 152.5 0.0 2.6e-44 151.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 KFQ98721.1 - 9e-42 142.2 0.1 1.6e-41 141.5 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 KFQ98721.1 - 4e-26 91.9 0.0 6.1e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.6 KFQ98721.1 - 7.4e-08 32.3 0.0 0.0064 16.1 0.0 2.3 2 0 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 KFQ98721.1 - 5.4e-06 26.1 0.4 0.11 12.4 0.0 3.6 4 0 0 4 4 4 2 PQQ enzyme repeat APH PF01636.23 KFQ98721.1 - 6.2e-06 26.3 0.2 0.033 14.1 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFQ98721.1 - 6.3e-06 25.2 0.0 0.00036 19.4 0.0 2.0 1 1 1 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KFQ98721.1 - 0.0011 18.4 0.1 0.0022 17.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ_3 PF13570.6 KFQ98721.1 - 0.054 14.0 0.6 3 8.5 0.0 3.9 4 1 1 5 5 5 0 PQQ-like domain RNA_pol_Rpb2_2 PF04561.14 KFQ98722.1 - 0.0018 17.9 0.3 0.0092 15.6 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 DUF244 PF03112.14 KFQ98722.1 - 0.11 12.3 2.6 0.17 11.7 0.5 2.2 2 0 0 2 2 2 0 Uncharacterized protein family (ORF7) DUF ANAPC3 PF12895.7 KFQ98722.1 - 0.26 11.5 3.2 0.38 11.0 1.4 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-C2H2_4 PF13894.6 KFQ98723.1 - 0.48 11.4 6.8 6.8 7.8 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-FCS PF06467.14 KFQ98723.1 - 0.71 9.9 3.9 0.39 10.7 1.3 2.0 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF3449 PF11931.8 KFQ98723.1 - 3.1 7.5 5.3 8 6.2 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) Njmu-R1 PF15053.6 KFQ98724.1 - 2.6e-179 595.8 0.2 2.9e-179 595.6 0.2 1.0 1 0 0 1 1 1 1 Mjmu-R1-like protein family Rhomboid PF01694.22 KFQ98725.1 - 8.2e-34 116.8 11.4 8.2e-34 116.8 11.4 1.9 2 0 0 2 2 2 1 Rhomboid family EF-hand_7 PF13499.6 KFQ98725.1 - 3.2e-09 37.1 0.0 5.1e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KFQ98725.1 - 7.1e-07 29.0 0.0 7.1e-05 22.6 0.0 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFQ98725.1 - 1.3e-06 27.5 0.0 0.0086 15.6 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_11 PF08976.11 KFQ98725.1 - 0.00032 21.5 0.0 0.00055 20.8 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain DUF5580 PF17743.1 KFQ98725.1 - 0.00043 18.9 0.0 0.00054 18.6 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) EF-hand_6 PF13405.6 KFQ98725.1 - 0.00088 19.0 0.1 0.056 13.4 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain DUF3087 PF11286.8 KFQ98725.1 - 0.068 12.6 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) DUF4203 PF13886.6 KFQ98725.1 - 2.4 7.8 16.8 2.7 7.6 3.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) ARL6IP6 PF15062.6 KFQ98725.1 - 4.5 7.5 5.6 1.6 8.9 0.2 2.5 3 0 0 3 3 3 0 Haemopoietic lineage transmembrane helix EF_assoc_2 PF08356.12 KFQ98726.1 - 9e-36 121.7 0.0 2.6e-35 120.3 0.0 1.8 2 0 0 2 2 1 1 EF hand associated EF_assoc_1 PF08355.12 KFQ98726.1 - 1.5e-29 101.4 0.7 9.9e-29 98.8 0.6 2.2 2 0 0 2 2 2 1 EF hand associated Ras PF00071.22 KFQ98726.1 - 4.1e-24 85.0 0.2 3.8e-16 59.1 0.0 2.7 2 1 0 2 2 2 2 Ras family Roc PF08477.13 KFQ98726.1 - 3.7e-08 33.6 0.0 6.3e-05 23.2 0.0 3.5 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 KFQ98726.1 - 1.1e-06 27.7 3.2 0.015 14.8 0.3 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFQ98726.1 - 2.4e-06 27.0 2.6 0.003 17.4 0.2 3.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KFQ98726.1 - 2.9e-06 27.6 1.6 0.011 16.1 0.0 3.1 3 1 0 3 3 2 2 EF-hand domain pair RsgA_GTPase PF03193.16 KFQ98726.1 - 6.3e-05 22.9 2.8 0.26 11.2 0.1 4.0 5 0 0 5 5 5 2 RsgA GTPase EF-hand_8 PF13833.6 KFQ98726.1 - 0.001 18.9 0.6 0.68 9.8 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain pair Rad4 PF03835.15 KFQ98726.1 - 0.0044 16.7 0.0 0.0092 15.7 0.0 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Dynamin_N PF00350.23 KFQ98726.1 - 0.025 14.7 0.1 0.66 10.0 0.0 2.4 2 0 0 2 2 2 0 Dynamin family MMR_HSR1 PF01926.23 KFQ98726.1 - 0.028 14.5 0.2 4.7 7.3 0.0 3.0 2 2 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 KFQ98726.1 - 0.095 12.7 0.0 5.7 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFQ98726.1 - 0.11 13.0 0.0 0.56 10.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter EF-hand_5 PF13202.6 KFQ98726.1 - 0.18 11.3 3.2 6.6 6.4 0.1 2.5 2 0 0 2 2 2 0 EF hand EF-hand_4 PF12763.7 KFQ98726.1 - 0.48 10.4 1.8 2.8 7.9 0.0 2.9 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand ArfGap PF01412.18 KFQ98727.1 - 9.5e-26 90.2 0.1 1.7e-25 89.3 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 KFQ98727.1 - 9e-21 74.4 0.1 7.8e-10 39.2 0.0 2.5 2 1 0 2 2 2 2 PH domain PH_11 PF15413.6 KFQ98727.1 - 7.5e-08 32.7 4.9 0.0033 17.8 0.2 3.9 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 KFQ98727.1 - 1.3e-07 31.8 4.0 0.0032 17.7 0.1 3.4 2 2 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.7 KFQ98727.1 - 0.031 14.4 0.0 0.22 11.7 0.0 2.3 2 1 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology AAA PF00004.29 KFQ98728.1 - 2.2e-07 31.4 5.7 2.6e-06 27.9 0.0 3.6 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFQ98728.1 - 0.00034 21.0 0.0 0.0014 19.0 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 KFQ98728.1 - 0.0019 18.2 11.7 0.073 13.0 0.0 3.9 4 0 0 4 4 4 2 Rad17 P-loop domain AAA_22 PF13401.6 KFQ98728.1 - 0.0059 16.9 0.1 0.031 14.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KFQ98728.1 - 0.0093 15.7 0.0 0.044 13.5 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KFQ98728.1 - 0.0098 16.4 1.8 0.096 13.2 0.0 3.5 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 KFQ98728.1 - 0.012 15.5 0.0 0.037 13.9 0.0 1.9 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.14 KFQ98728.1 - 0.1 12.6 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) fn3 PF00041.21 KFQ98729.1 - 0.0036 17.6 0.0 0.0063 16.8 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain VEFS-Box PF09733.9 KFQ98730.1 - 1.5e-54 183.5 2.9 3.2e-54 182.5 2.9 1.5 1 0 0 1 1 1 1 VEFS-Box of polycomb protein DUF2070 PF09843.9 KFQ98730.1 - 0.004 15.5 0.0 0.0059 15.0 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) zf-C2H2 PF00096.26 KFQ98730.1 - 7.4 7.2 6.5 28 5.4 6.5 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type U3_assoc_6 PF08640.11 KFQ98731.1 - 3.8e-15 55.7 4.7 3.8e-15 55.7 4.7 3.2 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 KFQ98731.1 - 3.2e-06 27.5 6.7 0.2 12.5 0.2 6.1 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ98731.1 - 0.014 16.0 0.3 5.2 7.8 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat HMGL-like PF00682.19 KFQ98731.1 - 0.032 13.8 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 HMGL-like vWF_A PF12450.8 KFQ98731.1 - 0.07 13.1 0.1 0.23 11.5 0.1 1.9 1 0 0 1 1 1 0 von Willebrand factor Mad3_BUB1_I PF08311.12 KFQ98731.1 - 0.78 9.7 13.9 2 8.4 0.3 5.2 3 2 0 4 4 4 0 Mad3/BUB1 homology region 1 RBD-FIP PF09457.10 KFQ98732.1 - 1.6e-17 63.1 3.3 1.6e-17 63.1 3.3 3.6 4 0 0 4 4 4 1 FIP domain bZIP_1 PF00170.21 KFQ98732.1 - 0.00012 22.1 6.1 0.00012 22.1 6.1 6.1 3 1 3 6 6 6 2 bZIP transcription factor ZapB PF06005.12 KFQ98732.1 - 0.0017 18.8 7.4 0.0017 18.8 7.4 5.3 4 2 1 5 5 5 2 Cell division protein ZapB bZIP_2 PF07716.15 KFQ98732.1 - 0.008 16.2 3.9 0.008 16.2 3.9 6.7 6 1 0 6 6 5 1 Basic region leucine zipper DUF682 PF05081.12 KFQ98732.1 - 0.052 13.3 0.7 0.13 12.0 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF682) Leu_zip PF15294.6 KFQ98732.1 - 0.081 12.4 42.3 0.19 11.2 25.9 3.1 2 1 1 3 3 3 0 Leucine zipper Imm49 PF15575.6 KFQ98732.1 - 0.2 11.4 3.2 0.14 11.9 0.9 1.9 2 0 0 2 2 2 0 Immunity protein 49 HAP1_N PF04849.13 KFQ98732.1 - 0.29 10.3 51.0 0.024 13.8 35.3 2.5 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Shugoshin_N PF07558.11 KFQ98732.1 - 0.44 10.4 17.9 0.31 10.9 1.3 4.8 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region VGPC1_C PF16799.5 KFQ98732.1 - 1.1 9.2 16.5 0.58 10.2 2.6 4.4 3 1 1 4 4 4 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Ax_dynein_light PF10211.9 KFQ98732.1 - 2.4 8.1 44.7 2.4 8.1 11.5 4.2 1 1 3 4 4 4 0 Axonemal dynein light chain DivIC PF04977.15 KFQ98732.1 - 3.8 7.3 37.8 0.031 14.0 2.7 5.5 4 2 1 6 6 6 0 Septum formation initiator PikAIV_N PF18605.1 KFQ98732.1 - 8.6 6.0 13.5 0.4 10.3 0.8 4.2 4 0 0 4 4 4 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain FlaC_arch PF05377.11 KFQ98732.1 - 9.8 6.7 30.7 0.33 11.4 0.9 5.5 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) Peptidase_S10 PF00450.22 KFQ98733.1 - 4.3e-84 283.3 1.1 4.9e-84 283.2 1.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 KFQ98733.1 - 0.035 13.4 0.0 0.53 9.5 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DAGK_acc PF00609.19 KFQ98735.1 - 8.7e-51 172.4 0.0 1.4e-50 171.8 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KFQ98735.1 - 7.6e-18 64.3 0.2 2.2e-17 62.9 0.2 1.7 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 KFQ98735.1 - 1.2e-07 31.5 39.3 0.00046 20.0 10.6 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4543 PF15076.6 KFQ98736.1 - 2e-44 149.6 1.1 2.4e-44 149.3 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4543) MmlI PF09448.10 KFQ98736.1 - 0.21 12.0 0.0 0.27 11.7 0.0 1.2 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase CTP_transf_like PF01467.26 KFQ98737.1 - 1.9e-37 128.6 0.0 1.6e-22 80.2 0.0 2.1 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 KFQ98737.1 - 0.0022 17.9 0.1 0.057 13.3 0.0 2.2 2 0 0 2 2 2 1 FAD synthetase CHAP PF05257.16 KFQ98737.1 - 0.012 16.1 0.1 0.051 14.1 0.1 2.1 1 1 0 1 1 1 0 CHAP domain SIR2 PF02146.17 KFQ98738.1 - 8.6e-25 87.7 2.8 1.9e-21 76.8 0.7 2.1 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 KFQ98738.1 - 0.0029 17.4 0.0 0.54 10.0 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain bZIP_Maf PF03131.17 KFQ98740.1 - 1.3e-33 115.4 11.7 1.6e-33 115.1 11.7 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 KFQ98740.1 - 3.5e-05 23.8 15.7 0.00035 20.6 15.7 2.3 1 1 0 1 1 1 1 bZIP transcription factor DivIC PF04977.15 KFQ98740.1 - 9.9e-05 22.0 5.8 9.9e-05 22.0 5.8 2.2 1 1 1 2 2 2 1 Septum formation initiator Prominin PF05478.11 KFQ98740.1 - 0.00039 18.6 1.4 0.00047 18.3 1.4 1.0 1 0 0 1 1 1 1 Prominin DUF1192 PF06698.11 KFQ98740.1 - 0.00056 19.9 5.7 0.024 14.7 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) DUF4164 PF13747.6 KFQ98740.1 - 0.0021 18.3 2.9 0.0021 18.3 2.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4164) DUF2353 PF09789.9 KFQ98740.1 - 0.003 17.0 5.9 0.0036 16.7 5.9 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Cnn_1N PF07989.11 KFQ98740.1 - 0.0061 16.7 8.7 0.014 15.6 8.7 1.7 1 1 0 1 1 1 1 Centrosomin N-terminal motif 1 JIP_LZII PF16471.5 KFQ98740.1 - 0.0071 16.5 2.6 0.0071 16.5 2.6 2.2 2 1 0 2 2 2 1 JNK-interacting protein leucine zipper II HAUS-augmin3 PF14932.6 KFQ98740.1 - 0.014 15.0 6.2 0.017 14.7 6.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 ThrE_2 PF12821.7 KFQ98740.1 - 0.015 15.4 0.1 0.022 14.9 0.1 1.1 1 0 0 1 1 1 0 Threonine/Serine exporter, ThrE FapA PF03961.13 KFQ98740.1 - 0.017 13.8 4.9 0.022 13.4 4.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Tox-ODYAM1 PF15642.6 KFQ98740.1 - 0.069 12.1 3.3 0.087 11.8 3.3 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus bZIP_2 PF07716.15 KFQ98740.1 - 0.074 13.1 16.8 0.11 12.5 13.4 2.7 1 1 1 2 2 2 0 Basic region leucine zipper Mod_r PF07200.13 KFQ98740.1 - 0.083 13.0 7.6 0.11 12.6 7.2 1.3 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein YabA PF06156.13 KFQ98740.1 - 0.11 13.2 8.4 0.055 14.1 3.7 2.1 1 1 1 2 2 2 0 Initiation control protein YabA DUF3584 PF12128.8 KFQ98740.1 - 0.22 9.0 8.4 0.25 8.8 8.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GIT_CC PF16559.5 KFQ98740.1 - 0.28 11.1 6.0 0.24 11.3 4.1 1.9 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4407 PF14362.6 KFQ98740.1 - 0.42 9.9 5.0 0.3 10.4 3.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DASH_Spc19 PF08287.11 KFQ98740.1 - 0.43 10.4 10.9 0.64 9.9 10.9 1.3 1 0 0 1 1 1 0 Spc19 Spc7 PF08317.11 KFQ98740.1 - 0.84 8.5 11.5 2.2 7.1 11.5 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein BST2 PF16716.5 KFQ98740.1 - 0.86 10.2 9.6 1.7 9.3 9.2 1.7 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Mst1_SARAH PF11629.8 KFQ98740.1 - 1 9.5 9.6 4.9 7.3 2.9 2.8 2 1 0 2 2 2 0 C terminal SARAH domain of Mst1 Nup54 PF13874.6 KFQ98740.1 - 1.1 9.4 8.9 1.5 8.9 8.9 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 ZapB PF06005.12 KFQ98740.1 - 1.3 9.5 16.4 1.3 9.5 8.8 2.6 1 1 1 2 2 2 0 Cell division protein ZapB Spc24 PF08286.11 KFQ98740.1 - 1.9 8.7 9.1 0.63 10.3 5.4 1.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF2205 PF10224.9 KFQ98740.1 - 2.1 8.4 9.8 0.73 9.9 4.9 2.1 1 1 1 2 2 2 0 Short coiled-coil protein APG6_N PF17675.1 KFQ98740.1 - 2.3 8.8 15.2 8.6 6.9 15.2 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4140 PF13600.6 KFQ98740.1 - 7.9 7.0 8.1 48 4.5 8.1 2.1 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) HALZ PF02183.18 KFQ98740.1 - 8.8 6.6 13.4 11 6.3 4.2 2.9 2 1 1 3 3 3 0 Homeobox associated leucine zipper P5CR_dimer PF14748.6 KFQ98741.1 - 1.7e-37 127.8 0.0 3.6e-37 126.8 0.0 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KFQ98741.1 - 7.2e-09 36.1 0.0 1.4e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KFQ98741.1 - 0.038 13.6 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PDH PF02153.17 KFQ98741.1 - 0.15 11.1 0.1 0.23 10.4 0.1 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase MARVEL PF01284.23 KFQ98742.1 - 1e-23 83.9 45.4 1.3e-13 51.2 15.2 2.1 2 0 0 2 2 2 2 Membrane-associating domain PAE PF03283.13 KFQ98743.1 - 4.3e-75 253.1 0.0 5.5e-75 252.7 0.0 1.1 1 0 0 1 1 1 1 Pectinacetylesterase UBX PF00789.20 KFQ98744.1 - 1.1e-11 44.7 0.0 4.1e-06 26.9 0.0 2.7 2 0 0 2 2 2 2 UBX domain TUG-UBL1 PF11470.8 KFQ98744.1 - 5e-07 29.8 0.1 1.1e-06 28.7 0.1 1.6 1 0 0 1 1 1 1 TUG ubiquitin-like domain LRR_6 PF13516.6 KFQ98745.1 - 4.9e-16 57.4 14.0 0.0015 18.4 0.2 5.7 5 0 0 5 5 5 4 Leucine Rich repeat LRR_1 PF00560.33 KFQ98745.1 - 0.00031 20.9 9.0 2.4 9.0 1.2 5.9 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.6 KFQ98745.1 - 0.0054 16.5 15.5 0.23 11.3 1.1 4.1 2 1 0 2 2 2 2 Leucine rich repeat MCR_D PF02505.14 KFQ98745.1 - 0.014 15.3 0.8 2.2 8.1 0.0 2.7 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein D LRR_4 PF12799.7 KFQ98745.1 - 0.45 11.0 16.9 0.96 10.0 3.0 4.0 1 1 3 4 4 4 0 Leucine Rich repeats (2 copies) Baculo_PEP_C PF04513.12 KFQ98745.1 - 5.4 7.0 33.8 0.039 14.0 2.7 4.0 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ras PF00071.22 KFQ98746.1 - 3.1e-50 169.9 0.0 3.6e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ98746.1 - 6.5e-19 68.3 0.0 8.5e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ98746.1 - 4e-05 23.1 0.0 4.9e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family CagD PF16567.5 KFQ98746.1 - 0.072 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Pathogenicity island component CagD adh_short_C2 PF13561.6 KFQ98747.1 - 6.3e-38 130.6 0.8 7.4e-38 130.4 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFQ98747.1 - 5.7e-33 114.0 0.1 7.1e-33 113.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.10 KFQ98747.1 - 0.077 12.3 0.0 0.089 12.1 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Fringe PF02434.16 KFQ98748.1 - 1.6e-120 401.2 0.0 1.9e-120 401.0 0.0 1.0 1 0 0 1 1 1 1 Fringe-like Glyco_transf_21 PF13506.6 KFQ98748.1 - 0.0077 15.7 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KFQ98748.1 - 0.013 15.4 0.0 0.084 12.7 0.0 2.0 1 1 0 1 1 1 0 Glycosyltransferase like family 2 Galactosyl_T PF01762.21 KFQ98748.1 - 0.025 14.4 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Galactosyltransferase RPN7 PF10602.9 KFQ98749.1 - 1.6e-63 213.5 0.5 3.4e-63 212.5 0.5 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KFQ98749.1 - 1.5e-17 64.0 1.2 6.9e-17 61.9 0.2 2.3 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 KFQ98749.1 - 0.0047 16.9 4.5 0.16 12.1 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFQ98749.1 - 0.035 13.8 1.0 0.12 12.1 0.0 2.4 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.28 KFQ98749.1 - 0.091 12.6 5.2 0.19 11.6 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Dus PF01207.17 KFQ98750.1 - 5.1e-47 160.5 0.0 7.5e-47 159.9 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF702 PF05142.12 KFQ98750.1 - 8.4e-05 23.1 5.3 0.00018 22.0 5.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF702) Ribosomal_S14 PF00253.21 KFQ98750.1 - 0.0034 17.1 1.0 0.0093 15.7 1.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e His_biosynth PF00977.21 KFQ98750.1 - 0.01 15.3 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Histidine biosynthesis protein TMP-TENI PF02581.17 KFQ98750.1 - 0.038 13.3 0.1 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 Thiamine monophosphate synthase NMO PF03060.15 KFQ98750.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Acyl_transf_1 PF00698.21 KFQ98751.1 - 8.3e-110 367.2 0.0 1.4e-109 366.5 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 KFQ98751.1 - 3.7e-70 236.4 0.0 6.5e-70 235.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thioesterase PF00975.20 KFQ98751.1 - 2.3e-60 204.6 0.9 8.2e-60 202.8 0.2 2.3 3 0 0 3 3 2 1 Thioesterase domain KR PF08659.10 KFQ98751.1 - 4.6e-45 153.7 0.0 1.6e-44 151.9 0.0 2.0 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 KFQ98751.1 - 6.5e-32 110.0 0.0 1.6e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KFQ98751.1 - 8.1e-28 97.1 0.0 2.1e-27 95.8 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KFQ98751.1 - 4e-18 65.6 0.0 1.7e-17 63.6 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PS-DH PF14765.6 KFQ98751.1 - 6.6e-18 65.0 0.0 1.5e-17 63.8 0.0 1.5 1 1 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.6 KFQ98751.1 - 1.1e-14 55.6 0.1 9.2e-14 52.6 0.0 2.7 3 0 0 3 3 1 1 Zinc-binding dehydrogenase PP-binding PF00550.25 KFQ98751.1 - 1.1e-08 35.3 0.6 2.8e-08 34.0 0.6 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 KFQ98751.1 - 1.4e-06 27.9 0.0 5.6e-05 22.7 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase Thiolase_N PF00108.23 KFQ98751.1 - 0.00039 19.9 0.0 0.00084 18.8 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_12 PF08242.12 KFQ98751.1 - 0.045 14.5 0.0 0.19 12.5 0.0 2.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KFQ98751.1 - 0.059 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain YjeF_N PF03853.15 KFQ98751.1 - 0.082 12.8 0.4 3 7.7 0.0 3.0 3 0 0 3 3 3 0 YjeF-related protein N-terminus Minor_tail_Z PF06763.11 KFQ98751.1 - 0.094 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Prophage minor tail protein Z (GPZ) AlaDh_PNT_C PF01262.21 KFQ98751.1 - 0.14 11.4 0.1 0.33 10.2 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain zf-CCHC_6 PF15288.6 KFQ98752.1 - 0.025 14.4 0.9 0.039 13.8 0.2 1.6 2 0 0 2 2 2 0 Zinc knuckle SRR1 PF07985.12 KFQ98752.1 - 0.091 12.8 0.4 0.23 11.5 0.4 1.7 1 1 0 1 1 1 0 SRR1 DivIC PF04977.15 KFQ98753.1 - 0.0058 16.4 0.8 0.0062 16.3 0.8 1.2 1 0 0 1 1 1 1 Septum formation initiator DUF4763 PF15960.5 KFQ98753.1 - 0.0075 15.6 0.4 0.0081 15.5 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) BLOC1S3 PF15753.5 KFQ98753.1 - 0.0076 16.4 0.4 0.0079 16.3 0.4 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 Med4 PF10018.9 KFQ98753.1 - 0.0077 15.9 0.5 0.0079 15.9 0.5 1.1 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Cnn_1N PF07989.11 KFQ98753.1 - 0.0081 16.3 0.4 0.0087 16.2 0.4 1.1 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 PI3K_P85_iSH2 PF16454.5 KFQ98753.1 - 0.01 15.4 1.0 0.011 15.3 1.0 1.0 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Atx10homo_assoc PF09759.9 KFQ98753.1 - 0.039 14.0 0.2 0.039 14.0 0.2 1.0 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain NYD-SP28_assoc PF14775.6 KFQ98753.1 - 0.098 12.8 1.3 0.12 12.4 0.5 1.7 1 1 1 2 2 2 0 Sperm tail C-terminal domain Pkinase PF00069.25 KFQ98754.1 - 2.8e-20 72.8 0.0 3.6e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ98754.1 - 7.4e-13 48.4 0.0 9.8e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFQ98754.1 - 6.3e-10 38.4 0.1 9.4e-10 37.8 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFQ98754.1 - 0.00034 20.6 0.0 0.0014 18.6 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KFQ98754.1 - 0.049 12.6 0.1 0.069 12.1 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KFQ98754.1 - 0.092 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_C1 PF00112.23 KFQ98757.1 - 5.4e-35 121.4 1.3 5.4e-35 121.4 1.3 2.1 2 0 0 2 2 2 1 Papain family cysteine protease Pacifastin_I PF05375.13 KFQ98757.1 - 0.00026 20.6 3.6 0.0013 18.5 3.6 2.2 1 0 0 1 1 1 1 Pacifastin inhibitor (LCMII) Propeptide_C1 PF08127.13 KFQ98757.1 - 0.00028 20.7 0.0 0.00063 19.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C1 propeptide BNR_6 PF15899.5 KFQ98757.1 - 0.15 12.1 0.5 2.2 8.5 0.1 2.7 2 0 0 2 2 2 0 BNR-Asp box repeat MLIP PF15274.6 KFQ98758.1 - 6.5e-111 370.2 1.9 1.2e-110 369.4 1.9 1.4 1 1 0 1 1 1 1 Muscular LMNA-interacting protein LRR_8 PF13855.6 KFQ98760.1 - 5e-31 106.3 37.8 2.6e-08 33.5 2.5 6.3 2 2 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 KFQ98760.1 - 3.2e-28 97.3 46.3 3e-05 24.3 0.0 8.4 6 1 3 9 9 9 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFQ98760.1 - 5.8e-10 38.9 17.3 0.00022 20.8 2.2 4.7 2 1 3 5 5 5 3 Leucine-rich repeat LRR_1 PF00560.33 KFQ98760.1 - 0.016 15.7 38.4 10 7.1 0.1 12.3 9 3 3 12 12 12 0 Leucine Rich Repeat Tropomyosin_1 PF12718.7 KFQ98760.1 - 0.055 13.6 3.1 0.14 12.3 3.1 1.6 1 0 0 1 1 1 0 Tropomyosin like DUF2322 PF10084.9 KFQ98760.1 - 0.19 11.8 0.3 3.6 7.7 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2322) HMw1_D2 PF18254.1 KFQ98760.1 - 0.26 11.7 1.6 5.7 7.4 0.1 3.8 4 1 0 4 4 4 0 HMW1 domain 2 H-kinase_dim PF02895.14 KFQ98760.1 - 0.93 9.9 5.2 0.3 11.5 0.3 2.8 3 2 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain LRR_6 PF13516.6 KFQ98760.1 - 2.7 8.2 31.0 12 6.2 0.1 9.4 10 0 0 10 10 10 0 Leucine Rich repeat Kelch_1 PF01344.25 KFQ98762.1 - 2.4e-45 151.8 11.7 1.8e-11 43.4 0.0 6.6 5 1 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 KFQ98762.1 - 1.2e-31 107.9 3.0 5.9e-08 32.7 0.2 6.1 3 1 3 6 6 6 5 Kelch motif BACK PF07707.15 KFQ98762.1 - 2e-25 88.9 0.1 4.6e-25 87.7 0.1 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 KFQ98762.1 - 4.3e-23 81.1 0.9 4.4e-06 26.8 0.0 5.0 5 0 0 5 5 5 4 Galactose oxidase, central domain BTB PF00651.31 KFQ98762.1 - 1.8e-21 76.5 0.6 4.4e-21 75.2 0.4 1.8 1 1 1 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 KFQ98762.1 - 9.8e-20 69.7 3.0 2.1e-07 30.6 0.2 6.4 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 KFQ98762.1 - 7.2e-18 64.3 0.5 0.00013 21.9 0.0 5.6 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFQ98762.1 - 1.1e-10 41.2 5.4 0.0034 17.3 0.1 5.4 5 0 0 5 5 5 3 Kelch motif Glyoxal_oxid_N PF07250.11 KFQ98762.1 - 0.00024 20.4 0.8 0.065 12.4 0.3 2.6 2 1 0 2 2 2 2 Glyoxal oxidase N-terminus PQQ_3 PF13570.6 KFQ98762.1 - 0.026 15.0 0.3 11 6.7 0.0 4.0 4 0 0 4 4 4 0 PQQ-like domain DUF1668 PF07893.13 KFQ98762.1 - 0.062 12.6 0.0 0.23 10.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1668) DnaJ PF00226.31 KFQ98762.1 - 0.12 12.5 0.0 0.85 9.8 0.0 2.2 2 0 0 2 2 2 0 DnaJ domain ThiG PF05690.14 KFQ98762.1 - 0.17 11.1 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG GCS PF03074.16 KFQ98764.1 - 7e-181 601.4 0.0 8.5e-181 601.2 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 KFQ98764.1 - 0.031 13.6 0.0 0.067 12.5 0.0 1.5 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) SANT_DAMP1_like PF16282.5 KFQ98764.1 - 0.067 13.4 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Glypican PF01153.19 KFQ98774.1 - 4.8e-206 685.9 0.0 5.6e-206 685.7 0.0 1.0 1 0 0 1 1 1 1 Glypican TGF_beta_GS PF08515.12 KFQ98774.1 - 2.8 7.5 4.1 6.9 6.3 4.1 1.7 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif GDP_Man_Dehyd PF16363.5 KFQ98776.1 - 5.9e-66 223.1 0.1 6.7e-66 223.0 0.1 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFQ98776.1 - 1.7e-55 188.1 0.1 2e-55 187.9 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFQ98776.1 - 8.6e-24 84.1 0.0 1e-23 83.8 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KFQ98776.1 - 5.2e-23 81.6 0.0 2.2e-22 79.6 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KFQ98776.1 - 5.3e-20 71.6 0.1 7.5e-20 71.1 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KFQ98776.1 - 7.4e-16 58.1 0.0 1.1e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KFQ98776.1 - 2.3e-06 27.6 0.0 3.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GpcrRhopsn4 PF10192.9 KFQ98777.1 - 6e-81 271.6 4.7 7.4e-81 271.3 4.7 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 KFQ98777.1 - 1.1e-08 34.7 2.5 2.1e-08 33.8 2.4 1.6 1 1 0 1 1 1 1 Lung seven transmembrane receptor PLAC8 PF04749.17 KFQ98777.1 - 0.006 17.6 1.3 0.006 17.6 1.3 2.4 3 0 0 3 3 3 1 PLAC8 family DUF1146 PF06612.11 KFQ98777.1 - 0.033 14.2 0.2 0.12 12.4 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1146) WHIM1 PF15612.6 KFQ98777.1 - 0.034 13.7 0.1 0.11 12.0 0.1 1.8 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 MraZ PF02381.18 KFQ98777.1 - 0.069 13.1 0.4 0.41 10.7 0.1 2.3 2 0 0 2 2 2 0 MraZ protein, putative antitoxin-like ABC_membrane PF00664.23 KFQ98778.1 - 1.8e-77 260.7 39.8 1.7e-46 159.1 13.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFQ98778.1 - 1.6e-51 174.4 0.1 5.8e-31 107.8 0.0 2.9 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFQ98778.1 - 5.8e-12 45.5 6.4 0.0012 18.3 0.6 4.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFQ98778.1 - 2.7e-08 34.4 0.2 0.0046 17.4 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KFQ98778.1 - 4.9e-07 29.8 0.1 0.0057 16.7 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KFQ98778.1 - 1.3e-06 28.1 0.0 0.04 13.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KFQ98778.1 - 1.4e-06 28.4 0.4 0.097 12.5 0.1 3.5 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KFQ98778.1 - 3.4e-06 27.4 1.0 0.24 11.7 0.0 4.2 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KFQ98778.1 - 4.3e-06 26.7 0.0 0.039 13.8 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KFQ98778.1 - 2.3e-05 24.5 0.0 0.027 14.5 0.0 2.7 2 0 0 2 2 2 2 Dynamin family AAA_7 PF12775.7 KFQ98778.1 - 0.00038 20.0 0.0 0.81 9.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 KFQ98778.1 - 0.0006 19.6 1.3 1.8 8.2 0.0 4.1 4 1 1 5 5 5 1 IstB-like ATP binding protein AAA_23 PF13476.6 KFQ98778.1 - 0.00079 20.0 0.0 0.38 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KFQ98778.1 - 0.002 17.3 0.0 0.076 12.1 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 KFQ98778.1 - 0.0053 16.5 0.5 2.5 7.8 0.1 3.0 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.17 KFQ98778.1 - 0.01 16.0 0.4 0.22 11.6 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain cobW PF02492.19 KFQ98778.1 - 0.024 14.2 0.2 2.7 7.6 0.1 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 KFQ98778.1 - 0.034 13.3 0.2 2 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SbcCD_C PF13558.6 KFQ98778.1 - 0.045 14.0 0.0 9 6.6 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 KFQ98778.1 - 0.081 13.3 0.5 10 6.6 0.0 3.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KFQ98778.1 - 0.093 12.0 0.2 9.1 5.5 0.1 2.6 2 0 0 2 2 2 0 Zeta toxin Guanylate_kin PF00625.21 KFQ98778.1 - 0.13 11.9 0.1 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 Guanylate kinase AAA_27 PF13514.6 KFQ98778.1 - 0.15 11.6 0.1 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KFQ98778.1 - 0.16 12.5 0.1 15 6.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 KFQ98778.1 - 0.29 11.3 1.3 12 6.2 0.0 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase Dzip-like_N PF13815.6 KFQ98779.1 - 1.5e-35 121.7 0.0 1.5e-35 121.7 0.0 6.6 4 2 3 7 7 7 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal Herpes_glycoH_C PF17488.2 KFQ98779.1 - 0.031 14.1 0.2 0.089 12.6 0.2 1.7 1 0 0 1 1 1 0 Herpesvirus glycoprotein H C-terminal domain zf-Di19 PF05605.12 KFQ98779.1 - 0.24 11.7 5.3 1.3 9.4 1.2 2.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KFQ98779.1 - 0.28 12.1 9.5 0.15 13.0 3.8 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger DUF384 PF04064.13 KFQ98779.1 - 0.64 9.9 2.9 4.1 7.3 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF384) zf-C2H2_3rep PF18868.1 KFQ98779.1 - 0.82 10.4 9.5 0.25 12.0 4.2 2.9 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2 PF00096.26 KFQ98779.1 - 5.4 7.7 12.2 0.079 13.4 4.1 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type TPR_1 PF00515.28 KFQ98780.1 - 2.5e-28 96.7 25.6 7e-07 28.8 0.0 9.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ98780.1 - 7e-28 94.5 26.7 0.00023 21.0 0.0 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_19 PF14559.6 KFQ98780.1 - 1.6e-25 89.4 21.9 7.9e-07 29.5 1.3 6.8 3 3 3 6 6 6 6 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ98780.1 - 8.9e-23 80.7 12.5 0.00024 21.7 0.8 6.5 5 1 1 6 6 6 5 Tetratricopeptide repeat DnaJ PF00226.31 KFQ98780.1 - 1.7e-21 76.1 2.0 1.7e-21 76.1 2.0 3.4 4 0 0 4 4 4 1 DnaJ domain TPR_11 PF13414.6 KFQ98780.1 - 6e-21 73.9 20.0 0.00027 20.6 0.5 8.2 6 1 2 8 8 8 6 TPR repeat TPR_9 PF13371.6 KFQ98780.1 - 1.1e-17 63.9 7.5 1.2e-05 25.3 0.4 5.1 4 2 1 5 5 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ98780.1 - 2e-17 62.4 17.8 0.017 15.9 0.0 9.6 4 3 6 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ98780.1 - 5.8e-17 60.4 25.6 0.0037 17.4 0.2 8.7 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ98780.1 - 6.9e-13 48.0 9.8 0.0012 19.0 0.0 6.9 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ98780.1 - 7.9e-12 45.3 23.4 0.026 14.8 0.1 7.4 3 2 5 8 8 8 7 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ98780.1 - 1.4e-11 44.5 17.9 0.0001 22.4 0.7 4.6 3 2 2 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KFQ98780.1 - 8.5e-11 41.8 21.3 0.47 11.2 0.2 9.7 10 1 0 10 10 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ98780.1 - 6.1e-09 35.3 14.3 4.4 7.6 0.0 8.6 6 2 3 9 9 9 1 Tetratricopeptide repeat TPR_20 PF14561.6 KFQ98780.1 - 8.3e-07 29.3 24.1 0.3 11.4 0.1 7.1 3 3 4 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 KFQ98780.1 - 0.00031 20.1 16.2 0.17 11.0 0.3 4.9 2 2 3 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFQ98780.1 - 0.015 15.4 14.6 9.9 6.3 0.0 6.0 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 KFQ98780.1 - 0.016 15.6 14.3 4.7 7.6 1.2 5.1 1 1 3 4 4 4 0 Bacterial transcriptional activator domain Alkyl_sulf_dimr PF14863.6 KFQ98780.1 - 0.073 13.5 14.8 1.9 8.9 1.5 5.3 2 1 3 6 6 6 0 Alkyl sulfatase dimerisation Virulence_fact PF13769.6 KFQ98780.1 - 0.093 13.0 2.8 0.26 11.5 0.1 3.1 2 1 1 3 3 2 0 Virulence factor TPR_4 PF07721.14 KFQ98780.1 - 0.2 12.4 12.8 1.1 10.0 0.0 6.0 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_3 PF07720.12 KFQ98780.1 - 1.2 9.2 5.1 2.8 8.0 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ98780.1 - 2.3 8.2 17.7 2.5 8.1 0.0 6.6 8 0 0 8 8 7 0 Tetratricopeptide repeat Vta1_C PF18097.1 KFQ98780.1 - 4.9 6.9 8.0 0.31 10.8 0.6 3.1 3 0 0 3 3 2 0 Vta1 C-terminal domain Glyco_transf_24 PF18404.1 KFQ98781.1 - 3.6e-148 492.2 4.6 7.6e-148 491.1 4.6 1.5 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_15 PF18403.1 KFQ98781.1 - 1e-68 231.4 4.4 5e-67 225.9 1.8 3.0 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_14 PF18402.1 KFQ98781.1 - 1.7e-63 215.0 3.2 9.2e-60 202.7 0.1 3.5 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KFQ98781.1 - 1.6e-41 142.3 0.1 3.4e-41 141.2 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KFQ98781.1 - 3.5e-40 136.5 0.0 9.3e-40 135.1 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 KFQ98781.1 - 6.7e-39 132.9 0.3 3.8e-38 130.5 0.1 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 KFQ98781.1 - 1.1e-06 28.4 0.9 1.1e-06 28.4 0.9 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 8 Sulfotransfer_2 PF03567.14 KFQ98784.1 - 3.3e-50 171.3 1.3 3.3e-50 171.3 1.3 1.6 2 0 0 2 2 2 1 Sulfotransferase family RNA_pol_Rbc25 PF08292.12 KFQ98784.1 - 0.13 12.5 0.3 0.2 11.9 0.3 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 7tm_1 PF00001.21 KFQ98785.1 - 2e-36 125.7 28.9 2.4e-36 125.4 28.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Abhydrolase_9_N PF15420.6 KFQ98785.1 - 0.33 10.9 5.2 0.53 10.2 5.2 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus zf-CCCH PF00642.24 KFQ98786.1 - 8.9e-11 41.4 24.8 0.00018 21.3 0.7 5.4 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KFQ98786.1 - 2.5e-06 27.8 24.8 0.25 11.9 1.5 4.7 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KFQ98786.1 - 2.8e-06 27.5 12.9 0.013 15.7 4.2 2.9 2 1 0 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 KFQ98786.1 - 0.0001 22.0 1.4 0.0001 22.0 1.4 5.3 5 2 0 5 5 5 3 CCCH-type zinc finger Torus PF16131.5 KFQ98786.1 - 0.00046 20.8 20.6 0.3 11.8 0.2 4.6 2 2 2 4 4 4 3 Torus domain zf_CCCH_4 PF18345.1 KFQ98786.1 - 0.0026 17.8 37.6 0.044 13.9 2.6 7.6 5 4 0 5 5 5 2 Zinc finger domain DUF3138 PF11336.8 KFQ98786.1 - 0.18 10.4 3.2 0.26 9.8 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Importin_rep_4 PF18808.1 KFQ98787.1 - 1.2e-26 92.7 1.7 1.2e-26 92.7 1.7 3.4 2 0 0 2 2 2 1 Importin repeat HEAT_EZ PF13513.6 KFQ98787.1 - 1.2e-18 67.2 5.2 1e-08 35.5 0.0 7.8 9 1 1 10 10 8 2 HEAT-like repeat HEAT PF02985.22 KFQ98787.1 - 4.1e-18 63.9 7.2 4.8e-05 23.3 0.0 8.4 9 0 0 9 9 8 3 HEAT repeat HEAT_2 PF13646.6 KFQ98787.1 - 1.8e-17 63.5 0.4 1.9e-08 34.6 0.0 6.7 4 2 2 6 6 6 2 HEAT repeats Vac14_Fab1_bd PF12755.7 KFQ98787.1 - 4.5e-13 49.6 6.9 2e-06 28.3 0.0 8.4 6 2 3 9 9 9 1 Vacuolar 14 Fab1-binding region Importin_rep_6 PF18829.1 KFQ98787.1 - 4.9e-12 45.9 1.5 3e-10 40.2 0.1 3.9 4 0 0 4 4 4 1 Importin repeat 6 Cnd1 PF12717.7 KFQ98787.1 - 4.5e-09 36.6 2.5 0.00083 19.4 0.1 4.6 3 2 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 KFQ98787.1 - 1.1e-06 28.6 4.5 1.9 8.4 0.1 8.0 6 2 4 10 10 10 1 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 KFQ98787.1 - 9.5e-05 21.1 3.5 0.011 14.4 0.3 3.5 3 1 0 4 4 4 2 Adaptin N terminal region IBN_N PF03810.19 KFQ98787.1 - 0.00017 21.4 3.0 0.0005 19.9 0.1 3.3 4 0 0 4 4 4 1 Importin-beta N-terminal domain Importin_rep_5 PF18816.1 KFQ98787.1 - 0.0012 19.1 0.1 0.052 13.9 0.0 3.0 2 0 0 2 2 2 1 Importin repeat Arm PF00514.23 KFQ98787.1 - 0.0042 17.1 3.5 8.2 6.6 0.0 5.6 6 0 0 6 6 5 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KFQ98787.1 - 0.024 14.8 1.7 1.5 9.0 0.0 4.4 5 1 0 5 5 4 0 Required for nuclear transport of RNA pol II C-terminus 1 PBP1_TM PF14812.6 KFQ98787.1 - 0.025 14.9 0.2 0.025 14.9 0.2 2.1 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sec7_N PF12783.7 KFQ98787.1 - 0.04 13.8 0.6 17 5.3 0.8 4.6 5 1 0 5 5 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal AbiJ_NTD5 PF18865.1 KFQ98787.1 - 0.1 12.4 0.1 0.96 9.3 0.4 2.6 2 0 0 2 2 1 0 AbiJ N-terminal domain 5 AAA_30 PF13604.6 KFQ98787.1 - 1.3 8.7 3.7 8.2 6.1 0.0 3.4 3 1 0 3 3 3 0 AAA domain HEAT_PBS PF03130.16 KFQ98787.1 - 8.2 7.4 7.8 34 5.5 0.0 4.8 5 1 0 5 5 3 0 PBS lyase HEAT-like repeat RhoGEF PF00621.20 KFQ98788.1 - 2.3e-31 109.4 1.7 5.3e-31 108.3 1.7 1.7 1 0 0 1 1 1 1 RhoGEF domain FERM_C PF09380.10 KFQ98788.1 - 1.9e-25 89.1 0.2 5e-25 87.7 0.2 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain PH PF00169.29 KFQ98788.1 - 5.3e-23 81.5 0.4 1.8e-13 50.9 0.6 2.9 2 0 0 2 2 2 2 PH domain FA PF08736.11 KFQ98788.1 - 5.1e-16 58.5 3.0 1.9e-15 56.6 3.0 2.1 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_M PF00373.18 KFQ98788.1 - 2.8e-12 47.1 0.7 2.8e-12 47.1 0.7 2.1 3 0 0 3 3 3 1 FERM central domain FERM_N PF09379.10 KFQ98788.1 - 1.2e-08 34.7 0.0 3e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain IQ_SEC7_PH PF16453.5 KFQ98788.1 - 2.7e-06 27.4 0.0 7.5e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 KFQ98788.1 - 0.00022 21.1 3.0 0.38 10.5 0.0 3.2 2 1 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 KFQ98788.1 - 0.086 13.3 3.9 0.86 10.1 1.4 3.7 3 1 0 3 3 3 0 Pleckstrin homology domain PH_2 PF08458.10 KFQ98788.1 - 0.14 12.5 0.3 43 4.5 0.0 3.6 3 0 0 3 3 3 0 Plant pleckstrin homology-like region Pkinase PF00069.25 KFQ98789.1 - 8.6e-52 176.1 0.0 1.2e-51 175.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ98789.1 - 6e-39 133.9 0.0 8.2e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFQ98789.1 - 1.2e-05 24.4 0.0 1.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase DUF1241 PF06840.11 KFQ98789.1 - 0.00016 21.4 0.0 0.00035 20.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Kinase-like PF14531.6 KFQ98789.1 - 0.023 14.0 0.0 0.051 12.9 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 KFQ98789.1 - 0.054 12.8 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RhoGAP PF00620.27 KFQ98791.1 - 1.9e-08 34.2 0.2 2.6e-08 33.9 0.2 1.2 1 0 0 1 1 1 1 RhoGAP domain ATP-synt_ab PF00006.25 KFQ98792.1 - 2.2e-103 344.5 0.0 2.7e-103 344.2 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain DED PF01335.21 KFQ98793.1 - 1.5e-17 63.7 0.5 3.8e-17 62.4 0.1 1.9 2 0 0 2 2 2 1 Death effector domain S_100 PF01023.19 KFQ98794.1 - 8.2e-17 60.6 0.9 1.1e-16 60.2 0.9 1.2 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_7 PF13499.6 KFQ98794.1 - 5.8e-05 23.5 0.2 6.7e-05 23.3 0.2 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFQ98794.1 - 0.0012 18.2 0.4 0.038 13.5 0.1 2.4 2 0 0 2 2 2 1 EF hand EFhand_Ca_insen PF08726.10 KFQ98794.1 - 0.1 12.7 0.3 0.15 12.1 0.1 1.5 2 0 0 2 2 2 0 Ca2+ insensitive EF hand EF-hand_8 PF13833.6 KFQ98794.1 - 0.11 12.4 1.1 0.7 9.8 0.7 2.1 1 1 1 2 2 2 0 EF-hand domain pair zf-C4 PF00105.18 KFQ98795.1 - 6.6e-30 103.4 9.5 7.1e-30 103.3 9.5 1.0 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) PX PF00787.24 KFQ98796.1 - 2.5e-19 69.3 0.1 5.3e-19 68.3 0.1 1.5 1 0 0 1 1 1 1 PX domain RA PF00788.23 KFQ98796.1 - 6.6e-12 45.9 0.0 2.4e-11 44.1 0.0 2.0 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain USP7_C2 PF14533.6 KFQ98796.1 - 0.0007 19.4 0.1 0.0012 18.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal SNX17_FERM_C PF18116.1 KFQ98796.1 - 0.004 17.2 0.1 0.014 15.5 0.1 1.9 1 0 0 1 1 1 1 Sorting Nexin 17 FERM C-terminal domain PDZ_6 PF17820.1 KFQ98796.1 - 0.022 14.6 0.1 0.049 13.5 0.1 1.6 1 0 0 1 1 1 0 PDZ domain bZIP_1 PF00170.21 KFQ98797.1 - 0.00045 20.3 16.1 0.0047 17.0 0.4 3.5 2 1 0 3 3 3 2 bZIP transcription factor KASH_CCD PF14662.6 KFQ98797.1 - 0.00047 20.0 15.9 0.00063 19.6 15.9 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Cast PF10174.9 KFQ98797.1 - 0.00048 18.5 10.9 0.00055 18.3 10.9 1.2 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DUF4200 PF13863.6 KFQ98797.1 - 0.0019 18.6 18.2 0.021 15.2 18.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4200) Fmp27_WPPW PF10359.9 KFQ98797.1 - 0.0055 15.6 7.0 0.0064 15.4 7.0 1.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF4686 PF15742.5 KFQ98797.1 - 0.014 14.5 16.7 0.021 14.0 16.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) Prominin PF05478.11 KFQ98797.1 - 0.015 13.3 1.2 0.016 13.2 1.2 1.1 1 0 0 1 1 1 0 Prominin Spc7 PF08317.11 KFQ98797.1 - 0.019 13.9 13.6 0.024 13.5 13.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein HSD3 PF15244.6 KFQ98797.1 - 0.021 14.4 4.1 0.026 14.1 4.1 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 DUF2937 PF11157.8 KFQ98797.1 - 0.029 14.1 4.2 0.051 13.3 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) SlyX PF04102.12 KFQ98797.1 - 0.031 14.9 6.2 0.031 14.9 6.2 3.2 1 1 2 3 3 3 0 SlyX Exonuc_VII_L PF02601.15 KFQ98797.1 - 0.032 13.8 6.9 0.038 13.6 6.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit VirC1 PF07015.11 KFQ98797.1 - 0.036 13.4 0.3 0.046 13.0 0.3 1.1 1 0 0 1 1 1 0 VirC1 protein Jnk-SapK_ap_N PF09744.9 KFQ98797.1 - 0.04 14.1 17.4 1.1 9.4 2.9 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 SpoIISA_toxin PF14171.6 KFQ98797.1 - 0.046 13.4 0.6 0.059 13.1 0.6 1.2 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Aminopep PF10023.9 KFQ98797.1 - 0.052 12.9 2.1 0.067 12.6 2.1 1.1 1 0 0 1 1 1 0 Putative aminopeptidase LCD1 PF09798.9 KFQ98797.1 - 0.053 12.0 4.8 0.078 11.5 4.8 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF4407 PF14362.6 KFQ98797.1 - 0.055 12.8 3.7 0.062 12.6 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CALCOCO1 PF07888.11 KFQ98797.1 - 0.065 12.1 16.9 0.085 11.7 16.9 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like HAUS-augmin3 PF14932.6 KFQ98797.1 - 0.069 12.7 11.5 0.12 11.9 11.5 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 MPS2 PF17060.5 KFQ98797.1 - 0.086 12.1 7.3 0.096 11.9 7.3 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 FapA PF03961.13 KFQ98797.1 - 0.088 11.4 7.0 0.11 11.1 7.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DNA_primase_lrg PF04104.14 KFQ98797.1 - 0.09 12.2 1.8 0.1 11.9 1.8 1.3 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit bZIP_2 PF07716.15 KFQ98797.1 - 0.099 12.7 0.9 0.099 12.7 0.9 3.6 3 2 0 3 3 3 0 Basic region leucine zipper DUF4988 PF16378.5 KFQ98797.1 - 0.1 12.2 3.3 3.9 7.1 0.7 2.3 1 1 1 2 2 2 0 Domain of unknown function Tropomyosin_1 PF12718.7 KFQ98797.1 - 0.16 12.1 16.2 0.2 11.8 14.5 1.7 1 1 0 1 1 1 0 Tropomyosin like DHR10 PF18595.1 KFQ98797.1 - 0.17 11.9 20.2 0.061 13.4 13.3 2.1 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF737 PF05300.11 KFQ98797.1 - 0.21 11.9 14.5 0.29 11.5 14.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) ADIP PF11559.8 KFQ98797.1 - 0.22 11.6 14.9 2.4 8.2 12.3 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding UPF0515 PF15135.6 KFQ98797.1 - 0.29 10.5 2.2 0.35 10.2 2.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 DUF1664 PF07889.12 KFQ98797.1 - 0.39 10.7 9.0 1.1 9.4 8.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CLZ PF16526.5 KFQ98797.1 - 0.42 11.0 18.1 2 8.8 9.5 3.2 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Med9 PF07544.13 KFQ98797.1 - 0.44 10.7 11.0 0.31 11.2 8.5 2.0 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF724 PF05266.14 KFQ98797.1 - 0.45 10.3 12.0 0.57 10.0 11.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 KFQ98797.1 - 0.48 8.3 7.3 0.56 8.0 7.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HMMR_N PF15905.5 KFQ98797.1 - 0.5 9.8 15.9 0.63 9.5 15.9 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Fib_alpha PF08702.10 KFQ98797.1 - 0.54 10.4 9.4 0.58 10.3 7.6 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.8 KFQ98797.1 - 0.55 10.3 19.1 0.79 9.8 9.2 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding CREPT PF16566.5 KFQ98797.1 - 0.59 10.3 11.5 0.87 9.8 11.5 1.3 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour AKNA PF12443.8 KFQ98797.1 - 0.75 10.5 6.5 1.1 9.9 4.8 2.2 1 1 1 2 2 2 0 AT-hook-containing transcription factor CCDC-167 PF15188.6 KFQ98797.1 - 0.8 10.1 16.2 0.82 10.0 3.4 2.9 1 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 E2F_CC-MB PF16421.5 KFQ98797.1 - 0.83 10.1 5.4 2.5 8.5 5.4 2.0 1 1 0 1 1 1 0 E2F transcription factor CC-MB domain Hemerythrin PF01814.23 KFQ98797.1 - 1.1 9.9 10.9 3.1 8.4 1.1 2.2 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain Atg14 PF10186.9 KFQ98797.1 - 1.1 8.2 13.9 2.3 7.2 14.0 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FAM76 PF16046.5 KFQ98797.1 - 1.1 8.5 11.7 2.2 7.6 11.6 1.6 1 1 0 1 1 1 0 FAM76 protein 7tm_7 PF08395.12 KFQ98797.1 - 1.2 8.3 1.8 1.5 7.9 1.8 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor Occludin_ELL PF07303.13 KFQ98797.1 - 1.2 9.9 7.0 1.1 10.1 5.3 1.8 1 1 1 2 2 2 0 Occludin homology domain Sec2p PF06428.11 KFQ98797.1 - 1.2 9.1 15.0 0.23 11.4 3.7 3.2 1 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p GrpE PF01025.19 KFQ98797.1 - 1.4 8.6 13.0 1.2 8.8 3.3 2.6 1 1 2 3 3 3 0 GrpE DUF4618 PF15397.6 KFQ98797.1 - 1.4 8.3 15.7 2.2 7.6 15.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) DUF1192 PF06698.11 KFQ98797.1 - 1.4 9.0 13.6 5 7.2 0.4 4.2 3 2 1 4 4 4 0 Protein of unknown function (DUF1192) ATG16 PF08614.11 KFQ98797.1 - 1.5 9.0 18.6 0.71 10.1 10.3 2.5 1 1 2 3 3 2 0 Autophagy protein 16 (ATG16) DUF4795 PF16043.5 KFQ98797.1 - 1.5 8.4 15.9 8.2 6.0 16.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF16 PF01519.16 KFQ98797.1 - 1.5 9.4 10.8 3 8.4 7.8 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF445 PF04286.12 KFQ98797.1 - 1.6 8.4 9.3 1.9 8.2 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) CorA PF01544.18 KFQ98797.1 - 1.7 7.9 6.8 2.2 7.5 6.8 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF848 PF05852.11 KFQ98797.1 - 1.8 8.7 11.7 0.27 11.3 2.8 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) CENP-F_leu_zip PF10473.9 KFQ98797.1 - 1.9 8.5 19.7 12 6.0 18.1 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.20 KFQ98797.1 - 2.2 8.3 16.4 2.4 8.2 3.9 3.1 1 1 2 3 3 3 0 Prefoldin subunit YabA PF06156.13 KFQ98797.1 - 2.5 8.8 13.3 0.7 10.6 3.7 2.6 1 1 1 2 2 2 0 Initiation control protein YabA UPF0242 PF06785.11 KFQ98797.1 - 2.9 8.0 16.0 4 7.5 16.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF641 PF04859.12 KFQ98797.1 - 3.8 7.8 13.2 13 6.1 8.8 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) kleA_kleC PF17383.2 KFQ98797.1 - 3.9 7.9 7.4 1.7 9.1 2.0 2.3 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A CENP-H PF05837.12 KFQ98797.1 - 3.9 7.9 15.7 14 6.1 10.0 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Lzipper-MIP1 PF14389.6 KFQ98797.1 - 4.6 7.6 17.6 0.86 9.9 10.7 2.5 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF3450 PF11932.8 KFQ98797.1 - 6 6.1 14.2 5.4 6.3 10.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FUSC PF04632.12 KFQ98797.1 - 8.3 4.8 5.3 9.8 4.6 5.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Proteasome PF00227.26 KFQ98798.1 - 2.1e-32 112.2 0.0 2.4e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Glycos_trans_3N PF02885.17 KFQ98798.1 - 0.061 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain zf-C2H2_4 PF13894.6 KFQ98799.1 - 5e-12 45.6 51.8 0.023 15.5 0.6 7.6 7 0 0 7 7 7 5 C2H2-type zinc finger zf-Di19 PF05605.12 KFQ98799.1 - 3.2e-05 24.1 40.8 0.022 15.0 0.4 5.3 4 1 1 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KFQ98799.1 - 0.00086 19.6 56.1 0.2 12.2 0.2 7.6 7 1 0 7 7 7 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ98799.1 - 0.0077 16.6 5.3 0.055 13.9 0.3 6.7 9 0 0 9 9 7 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFQ98799.1 - 0.07 13.4 31.0 0.15 12.4 0.5 6.1 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.15 KFQ98799.1 - 0.14 12.1 0.1 0.14 12.1 0.1 4.6 4 1 1 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain FYVE PF01363.21 KFQ98799.1 - 0.19 11.9 0.0 0.19 11.9 0.0 4.9 3 1 1 4 4 3 0 FYVE zinc finger zf-C2H2_11 PF16622.5 KFQ98799.1 - 0.54 10.1 0.0 0.54 10.1 0.0 4.4 5 0 0 5 5 5 0 zinc-finger C2H2-type FOXP-CC PF16159.5 KFQ98799.1 - 0.72 10.5 19.3 2.8 8.7 0.1 4.6 2 1 2 4 4 4 0 FOXP coiled-coil domain Rubredoxin PF00301.20 KFQ98799.1 - 0.77 9.8 0.0 0.77 9.8 0.0 5.9 7 0 0 7 7 7 0 Rubredoxin zinc_ribbon_15 PF17032.5 KFQ98799.1 - 2.5 8.9 22.8 0.35 11.6 0.4 4.5 3 2 2 5 5 5 0 zinc-ribbon family zinc_ribbon_5 PF13719.6 KFQ98799.1 - 9.2 6.1 10.5 4.6 7.1 0.2 4.1 4 0 0 4 4 4 0 zinc-ribbon domain SBP56 PF05694.11 KFQ98800.1 - 3.4e-214 711.8 0.0 3.9e-214 711.6 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 KFQ98800.1 - 0.0022 17.3 0.0 0.0081 15.5 0.0 1.8 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Pentapeptide_4 PF13599.6 KFQ98801.1 - 0.004 17.3 0.0 1.1 9.4 0.0 2.0 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) DUF2924 PF11149.8 KFQ98801.1 - 0.62 10.4 3.9 3.2 8.1 3.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2924) SBP56 PF05694.11 KFQ98802.1 - 1.1e-138 462.8 0.0 1.3e-138 462.7 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 KFQ98802.1 - 0.0026 17.1 0.0 0.011 15.0 0.0 1.8 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller SBP56 PF05694.11 KFQ98803.1 - 1.1e-210 700.3 0.0 2.8e-210 698.9 0.0 1.6 1 1 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 KFQ98803.1 - 0.00034 20.0 0.0 0.0015 17.8 0.0 1.9 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller RFX_DNA_binding PF02257.15 KFQ98804.1 - 3.8e-29 101.1 0.1 4.7e-29 100.8 0.1 1.1 1 0 0 1 1 1 1 RFX DNA-binding domain RFX5_N PF18326.1 KFQ98804.1 - 6.6e-15 54.6 2.3 9.8e-15 54.1 2.3 1.3 1 0 0 1 1 1 1 RFX5 N-terminal domain Pox_D5 PF03288.16 KFQ98804.1 - 0.0005 20.5 0.0 0.00083 19.8 0.0 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like UIM PF02809.20 KFQ98805.1 - 1.9e-08 33.6 6.0 0.0001 21.9 0.4 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif VWA_2 PF13519.6 KFQ98805.1 - 4.4e-06 27.3 1.1 3.7e-05 24.3 0.0 3.0 3 1 1 4 4 4 1 von Willebrand factor type A domain RAP80_UIM PF18282.1 KFQ98805.1 - 0.023 14.4 3.0 0.023 14.4 3.0 2.6 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif PIP5K PF01504.18 KFQ98806.1 - 1.9e-91 306.1 0.0 2.3e-91 305.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase YL1 PF05764.13 KFQ98807.1 - 4e-26 92.6 9.4 5.4e-26 92.2 9.4 1.1 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.11 KFQ98807.1 - 1.7e-12 46.9 0.8 3.5e-12 45.9 0.8 1.6 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DNA_methylase PF00145.17 KFQ98807.1 - 0.0053 16.1 0.3 0.0064 15.9 0.3 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Tropomodulin PF03250.14 KFQ98808.1 - 9.8e-16 58.1 0.0 1.9e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Tropomodulin LRR_6 PF13516.6 KFQ98808.1 - 0.15 12.2 0.0 0.15 12.2 0.0 3.7 4 0 0 4 4 4 0 Leucine Rich repeat SCNM1_acidic PF15805.5 KFQ98809.1 - 5.5e-18 64.4 0.6 1.1e-17 63.5 0.6 1.5 1 0 0 1 1 1 1 Acidic C-terminal region of sodium channel modifier 1 SCNM1 zf-SCNM1 PF15803.5 KFQ98809.1 - 8.4e-16 57.3 2.0 1.8e-15 56.3 2.0 1.6 1 0 0 1 1 1 1 Zinc-finger of sodium channel modifier 1 Ank_2 PF12796.7 KFQ98810.1 - 5e-29 100.7 0.6 9.2e-15 55.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFQ98810.1 - 5.1e-21 72.5 0.3 2.6e-06 27.3 0.1 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KFQ98810.1 - 7.9e-20 71.0 2.0 4.7e-11 43.0 0.4 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFQ98810.1 - 9.8e-20 70.1 2.1 4.3e-07 30.1 0.2 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KFQ98810.1 - 5.9e-19 67.9 1.0 9.2e-09 35.4 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) CK1gamma_C PF12605.8 KFQ98810.1 - 1.2 10.4 6.6 12 7.1 1.1 2.8 2 1 0 2 2 2 0 Casein kinase 1 gamma C terminal PBD PF00786.28 KFQ98811.1 - 0.00017 21.9 0.1 0.00031 21.0 0.1 1.4 1 0 0 1 1 1 1 P21-Rho-binding domain CRAL_TRIO_2 PF13716.6 KFQ98812.1 - 4.3e-25 88.5 0.0 4.7e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KFQ98812.1 - 6.7e-07 29.2 0.0 1.1e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 CRAL/TRIO domain TRAM_LAG1_CLN8 PF03798.16 KFQ98813.1 - 2.3e-37 128.7 22.7 6.1e-36 124.0 22.6 2.1 2 0 0 2 2 2 1 TLC domain TraP PF07296.11 KFQ98813.1 - 0.083 12.1 1.2 0.36 10.0 0.2 2.0 2 0 0 2 2 2 0 TraP protein DUF5604 PF18300.1 KFQ98814.1 - 2e-18 66.1 1.1 3.8e-18 65.2 1.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5604) DUF948 PF06103.11 KFQ98814.1 - 0.0037 17.5 1.6 1.3 9.3 0.0 2.7 2 1 0 2 2 2 2 Bacterial protein of unknown function (DUF948) PIN_3 PF13470.6 KFQ98814.1 - 0.042 14.6 1.4 0.11 13.2 1.4 1.7 1 0 0 1 1 1 0 PIN domain YkyA PF10368.9 KFQ98814.1 - 0.068 12.8 16.6 0.084 12.5 11.2 2.3 2 1 0 2 2 2 0 Putative cell-wall binding lipoprotein P4Ha_N PF08336.11 KFQ98814.1 - 0.1 12.6 3.3 0.93 9.5 0.5 2.3 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF2203 PF09969.9 KFQ98814.1 - 0.23 12.2 5.6 0.85 10.4 2.7 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF3391 PF11871.8 KFQ98814.1 - 0.39 11.3 8.4 3.6 8.1 0.1 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3391) Phytochelatin PF05023.14 KFQ98814.1 - 0.41 9.8 2.8 0.42 9.8 0.7 1.8 2 0 0 2 2 2 0 Phytochelatin synthase Laminin_II PF06009.12 KFQ98814.1 - 0.41 10.7 7.3 0.13 12.2 1.6 2.5 2 1 0 2 2 2 0 Laminin Domain II DUF4164 PF13747.6 KFQ98814.1 - 0.55 10.6 0.2 0.55 10.6 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) CR6_interact PF10147.9 KFQ98814.1 - 0.8 9.4 0.1 0.8 9.4 0.1 2.3 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 BLOC1_2 PF10046.9 KFQ98814.1 - 1 9.7 9.2 5.4 7.4 3.5 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-C4H2 PF10146.9 KFQ98814.1 - 3.2 8.0 11.5 9.2 6.5 11.5 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein TMF_DNA_bd PF12329.8 KFQ98814.1 - 3.8 7.6 16.8 0.069 13.2 3.0 3.3 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding TMPIT PF07851.13 KFQ98814.1 - 7.8 5.6 7.0 3.4 6.8 3.6 2.0 2 0 0 2 2 2 0 TMPIT-like protein PAS_3 PF08447.12 KFQ98815.1 - 4.1e-24 84.7 0.0 2.2e-18 66.3 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KFQ98815.1 - 3.6e-22 78.6 0.3 8.5e-20 71.0 0.3 2.7 2 1 0 2 2 2 1 PAS domain PAS PF00989.25 KFQ98815.1 - 1.1e-20 73.7 0.0 6.7e-13 48.6 0.0 2.5 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 KFQ98815.1 - 3.9e-14 52.3 1.1 1.4e-13 50.5 1.1 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 KFQ98815.1 - 8.6e-10 38.8 0.0 9.2e-07 29.1 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KFQ98815.1 - 0.0018 18.5 0.0 1 9.7 0.0 2.6 2 0 0 2 2 2 2 PAS fold HAUS2 PF15003.6 KFQ98815.1 - 0.22 11.3 0.0 0.41 10.4 0.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 Peptidase_C1 PF00112.23 KFQ98816.1 - 1.8e-76 257.0 0.6 2e-76 256.9 0.6 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KFQ98816.1 - 3.4e-07 29.4 2.0 0.00022 20.2 0.5 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 KFQ98817.1 - 1.3e-79 267.4 3.3 1.6e-79 267.0 3.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KFQ98817.1 - 1.2e-10 41.7 0.0 1.8e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KFQ98817.1 - 8.8e-06 24.7 1.3 0.0073 15.1 0.1 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 KFQ98818.1 - 9.9e-83 277.5 2.3 1.2e-82 277.2 2.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KFQ98818.1 - 3.7e-10 40.1 0.0 6.2e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KFQ98818.1 - 0.00018 20.5 1.1 0.15 10.8 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family PINIT PF14324.6 KFQ98819.1 - 4.2e-37 127.7 0.2 6.9e-37 127.0 0.2 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KFQ98819.1 - 1.7e-21 75.7 5.2 3.9e-21 74.5 5.2 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KFQ98819.1 - 4.3e-05 23.3 1.6 0.0001 22.1 1.6 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 KFQ98819.1 - 0.019 14.7 0.1 0.048 13.4 0.1 1.7 1 0 0 1 1 1 0 SAP domain Prok-RING_4 PF14447.6 KFQ98819.1 - 1.1 9.2 8.0 0.061 13.2 1.9 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 HTH_9 PF08221.11 KFQ98820.1 - 1.1e-06 28.6 0.8 2.2e-06 27.6 0.7 1.6 1 1 1 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain zf-RING_2 PF13639.6 KFQ98821.1 - 2.8e-13 50.0 7.8 2.8e-13 50.0 7.8 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFQ98821.1 - 8.1e-09 35.2 7.7 8.1e-09 35.2 7.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFQ98821.1 - 4.2e-08 32.8 3.1 4.2e-08 32.8 3.1 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KFQ98821.1 - 1.5e-07 31.4 4.5 4.4e-07 29.8 2.3 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 KFQ98821.1 - 1.3e-06 28.6 8.8 1.3e-06 28.6 8.8 2.0 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFQ98821.1 - 1.9e-06 27.7 5.7 1.9e-06 27.7 5.7 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFQ98821.1 - 3.1e-06 27.0 6.8 3.1e-06 27.0 6.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFQ98821.1 - 2e-05 24.4 3.3 2e-05 24.4 3.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFQ98821.1 - 8e-05 22.6 6.5 0.00032 20.7 3.6 2.7 3 1 0 3 3 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KFQ98821.1 - 0.0028 17.5 10.6 0.012 15.5 8.0 2.8 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zinc_ribbon_9 PF14369.6 KFQ98821.1 - 0.0059 16.8 7.2 0.0063 16.8 0.6 3.1 3 0 0 3 3 3 1 zinc-ribbon zf-Nse PF11789.8 KFQ98821.1 - 0.032 14.1 3.8 0.069 13.0 3.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-HC5HC2H_2 PF13832.6 KFQ98821.1 - 0.15 12.3 2.4 0.12 12.6 0.6 1.7 1 1 1 2 2 2 0 PHD-zinc-finger like domain Rad50_zn_hook PF04423.14 KFQ98821.1 - 0.15 11.9 7.6 0.46 10.3 0.3 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-RING_6 PF14835.6 KFQ98821.1 - 0.15 11.9 3.1 0.53 10.2 3.1 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-HC5HC2H PF13771.6 KFQ98821.1 - 0.19 12.0 3.0 0.14 12.5 0.6 1.8 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-H2C2_2 PF13465.6 KFQ98821.1 - 0.45 11.0 6.2 39 4.9 0.3 3.4 3 0 0 3 3 3 0 Zinc-finger double domain Vps39_2 PF10367.9 KFQ98821.1 - 0.47 10.9 3.0 4.5 7.8 0.9 2.5 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Opy2 PF09463.10 KFQ98821.1 - 0.48 10.8 6.5 21 5.5 0.3 3.2 3 0 0 3 3 3 0 Opy2 protein zf-ribbon_3 PF13248.6 KFQ98821.1 - 0.6 9.6 3.4 23 4.5 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_4 PF14570.6 KFQ98821.1 - 0.63 9.9 8.6 4.9 7.0 0.0 3.0 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain HypA PF01155.19 KFQ98821.1 - 0.64 10.0 2.9 1.7 8.7 1.1 2.1 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Di19 PF05605.12 KFQ98821.1 - 0.69 10.3 13.4 15 6.0 8.4 3.1 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF983 PF06170.12 KFQ98821.1 - 0.73 10.3 3.8 18 5.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF983) DZR PF12773.7 KFQ98821.1 - 1.4 9.0 4.8 7.2 6.7 1.8 2.7 2 1 0 2 2 2 0 Double zinc ribbon Baculo_IE-1 PF05290.11 KFQ98821.1 - 1.7 8.6 4.6 1.5 8.7 1.5 2.2 2 1 0 2 2 1 0 Baculovirus immediate-early protein (IE-0) Zn_Tnp_IS1595 PF12760.7 KFQ98821.1 - 2.5 8.1 6.4 33 4.6 0.9 3.2 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Zn_ribbon_17 PF17120.5 KFQ98821.1 - 3.9 7.2 10.2 0.15 11.7 4.3 1.7 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type TF_Zn_Ribbon PF08271.12 KFQ98821.1 - 4.3 6.9 7.5 16 5.1 0.2 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding PHD PF00628.29 KFQ98821.1 - 4.5 7.2 9.9 12 5.9 5.2 2.8 2 1 0 2 2 2 0 PHD-finger zinc-ribbons_6 PF07191.12 KFQ98821.1 - 4.6 7.3 6.6 10 6.2 3.0 2.4 2 1 0 2 2 2 0 zinc-ribbons Zn-C2H2_12 PF18112.1 KFQ98821.1 - 5.4 7.6 9.8 6.4 7.3 0.2 3.7 4 0 0 4 4 3 0 Autophagy receptor zinc finger-C2H2 domain Prok-RING_1 PF14446.6 KFQ98821.1 - 6.9 6.7 9.0 7.6 6.5 0.1 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zinc_ribbon_4 PF13717.6 KFQ98821.1 - 8.8 6.4 7.8 9 6.3 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain PEX11 PF05648.14 KFQ98822.1 - 6.3e-74 248.2 0.5 7e-74 248.0 0.5 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) TPR_2 PF07719.17 KFQ98822.1 - 0.065 13.4 0.2 0.18 12.0 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat LIX1 PF14954.6 KFQ98823.1 - 2.3e-133 443.1 0.3 2.6e-133 442.9 0.3 1.0 1 0 0 1 1 1 1 Limb expression 1 CCDC158 PF15921.5 KFQ98823.1 - 0.0047 14.8 0.2 0.0059 14.5 0.2 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 158 Dicer_dimer PF03368.14 KFQ98823.1 - 0.038 14.2 0.0 0.087 13.0 0.0 1.6 1 0 0 1 1 1 0 Dicer dimerisation domain RRM_1 PF00076.22 KFQ98824.1 - 5.3e-19 67.8 0.0 9.3e-19 67.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFQ98824.1 - 1.2e-06 28.5 0.0 2.4e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.6 KFQ98824.1 - 4.2e-05 23.1 0.0 5.5e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lectin_C PF00059.21 KFQ98853.1 - 1.5e-12 48.2 0.7 1.8e-12 48.0 0.2 1.4 2 0 0 2 2 2 1 Lectin C-type domain Ribosomal_L13 PF00572.18 KFQ98853.1 - 0.077 13.3 0.1 0.092 13.0 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L13 Lectin_C PF00059.21 KFQ98854.1 - 1.2e-19 71.1 1.6 1.2e-19 71.1 1.6 1.7 1 1 1 2 2 2 1 Lectin C-type domain UL45 PF05473.12 KFQ98854.1 - 0.098 12.3 0.9 0.39 10.3 1.2 2.0 2 1 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like DUF1681 PF07933.14 KFQ98855.1 - 1.6e-57 193.4 0.0 2e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Sugar_tr PF00083.24 KFQ98856.1 - 3.3e-161 537.1 26.0 3.7e-161 537.0 26.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFQ98856.1 - 3.2e-20 72.4 33.8 9.6e-19 67.5 27.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 KFQ98856.1 - 10 6.8 11.1 0.49 11.0 4.2 2.4 3 0 0 3 3 3 0 Phage holin family 2 Tubulin PF00091.25 KFQ98858.1 - 2.7e-59 200.7 0.0 4.2e-59 200.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFQ98858.1 - 8.3e-43 145.6 0.1 1.3e-42 144.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFQ98858.1 - 0.0067 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KFQ98858.1 - 0.015 14.6 0.0 0.031 13.5 0.0 1.5 1 0 0 1 1 1 0 Tubulin like Ribosomal_S7 PF00177.21 KFQ98860.1 - 1.2e-06 28.3 0.1 1.5e-06 28.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_S7 PF00177.21 KFQ98861.1 - 3.6e-16 59.1 0.1 3.9e-16 59.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e 7tm_3 PF00003.22 KFQ98862.1 - 1.7e-50 172.0 7.7 2.4e-50 171.5 7.7 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 KFQ98862.1 - 5.1e-44 150.8 0.0 3.3e-26 92.2 0.0 2.3 2 1 0 2 2 2 2 Receptor family ligand binding region Peripla_BP_6 PF13458.6 KFQ98862.1 - 2.1e-08 34.2 0.0 2.6e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 Periplasmic binding protein UPF0242 PF06785.11 KFQ98862.1 - 0.00025 21.2 0.6 0.00078 19.6 0.6 1.8 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Kei1 PF08552.11 KFQ98862.1 - 0.012 15.5 2.1 2.4 8.0 0.1 2.9 3 0 0 3 3 3 0 Inositolphosphorylceramide synthase subunit Kei1 Viral_env_E26 PF11050.8 KFQ98862.1 - 0.023 14.0 0.2 0.043 13.2 0.2 1.3 1 0 0 1 1 1 0 Virus envelope protein E26 DUF3995 PF13160.6 KFQ98862.1 - 0.027 14.8 0.5 0.027 14.8 0.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3995) NEMP PF10225.9 KFQ98862.1 - 0.032 13.9 0.4 0.032 13.9 0.4 2.0 2 0 0 2 2 2 0 NEMP family LRRC37AB_C PF14914.6 KFQ98862.1 - 0.055 13.4 1.1 2.9 7.8 0.0 2.6 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain PKcGMP_CC PF16808.5 KFQ98862.1 - 0.15 12.0 8.2 0.42 10.5 8.2 1.8 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4407 PF14362.6 KFQ98862.1 - 0.29 10.4 4.1 0.6 9.4 4.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TctB PF07331.11 KFQ98862.1 - 1.8 8.9 18.7 0.49 10.7 1.1 3.2 1 1 1 3 3 3 0 Tripartite tricarboxylate transporter TctB family KxDL PF10241.9 KFQ98862.1 - 2 8.7 6.7 1.6 9.1 4.5 1.9 2 0 0 2 2 1 0 Uncharacterized conserved protein zf-H2C2_2 PF13465.6 KFQ98863.1 - 7.3e-59 193.7 62.4 5.9e-11 42.3 0.8 8.6 9 0 0 9 9 8 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ98863.1 - 1.2e-42 142.0 81.6 3.4e-07 30.3 1.9 8.4 9 0 0 9 9 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ98863.1 - 1.3e-28 97.2 69.0 0.0008 20.0 0.9 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFQ98863.1 - 8.5e-12 45.0 33.9 0.0017 18.4 4.7 6.2 4 3 1 5 5 5 4 Zinc ribbon domain zf-C2H2_11 PF16622.5 KFQ98863.1 - 4.3e-10 39.2 50.1 2.8e-06 26.9 0.5 7.9 8 0 0 8 8 8 3 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFQ98863.1 - 2.3e-09 37.0 58.3 0.045 13.8 2.7 8.8 8 1 0 8 8 8 4 C2H2-type zinc finger zf_UBZ PF18439.1 KFQ98863.1 - 3.3e-08 33.0 37.2 0.49 10.0 0.1 8.2 8 0 0 8 8 8 5 Ubiquitin-Binding Zinc Finger DUF3268 PF11672.8 KFQ98863.1 - 1.6e-07 31.7 17.0 0.038 14.3 1.2 4.3 2 1 2 4 4 4 3 zinc-finger-containing domain zf-C2H2_jaz PF12171.8 KFQ98863.1 - 2.3e-07 30.9 38.5 0.026 14.8 1.6 8.1 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 KFQ98863.1 - 4.1e-06 26.6 44.7 0.059 13.3 0.4 8.3 8 1 0 8 8 8 4 LYAR-type C2HC zinc finger zf-AN1 PF01428.16 KFQ98863.1 - 4.3e-06 26.8 42.1 2.9 8.1 4.4 8.3 7 1 1 8 8 8 1 AN1-like Zinc finger zf-Di19 PF05605.12 KFQ98863.1 - 2.1e-05 24.7 36.9 0.11 12.8 4.2 5.5 3 1 3 6 6 6 4 Drought induced 19 protein (Di19), zinc-binding CpXC PF14353.6 KFQ98863.1 - 8.2e-05 22.6 31.1 0.16 12.0 3.2 7.1 3 3 3 7 7 7 1 CpXC protein zf-trcl PF13451.6 KFQ98863.1 - 9.6e-05 22.2 33.3 2.1 8.3 0.1 7.7 8 0 0 8 8 8 4 Probable zinc-ribbon domain ADK_lid PF05191.14 KFQ98863.1 - 0.00015 21.7 22.4 0.36 10.9 0.1 5.8 4 2 2 6 6 6 2 Adenylate kinase, active site lid HypA PF01155.19 KFQ98863.1 - 0.00019 21.4 25.4 0.75 9.8 2.4 4.8 1 1 4 5 5 5 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA XPA_N PF01286.18 KFQ98863.1 - 0.00039 20.4 35.3 0.69 10.0 0.1 8.0 8 0 0 8 8 8 2 XPA protein N-terminal C1_1 PF00130.22 KFQ98863.1 - 0.0008 19.2 39.8 1.4 8.8 1.5 7.0 3 2 5 8 8 8 5 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_15 PF17032.5 KFQ98863.1 - 0.00098 19.8 28.5 1.1 10.1 1.9 4.5 1 1 5 6 6 6 5 zinc-ribbon family FYDLN_acid PF09538.10 KFQ98863.1 - 0.0013 19.4 26.2 1.7 9.4 2.3 7.3 1 1 5 6 6 6 1 Protein of unknown function (FYDLN_acid) C1_4 PF07975.12 KFQ98863.1 - 0.0023 18.1 36.2 0.26 11.6 0.4 5.8 1 1 4 6 6 6 2 TFIIH C1-like domain zf-C2H2_3rep PF18868.1 KFQ98863.1 - 0.0027 18.4 26.7 0.024 15.3 7.4 4.7 2 2 3 5 5 5 1 Zinc finger C2H2-type, 3 repeats LIM PF00412.22 KFQ98863.1 - 0.0054 16.9 33.0 3.5 7.9 3.7 6.5 4 2 1 5 5 5 1 LIM domain DUF2256 PF10013.9 KFQ98863.1 - 0.0075 16.4 39.8 0.47 10.6 1.6 7.9 7 1 1 8 8 8 2 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_9 PF14369.6 KFQ98863.1 - 0.018 15.3 30.8 7.8 6.8 0.3 8.0 8 0 0 8 8 8 0 zinc-ribbon zinc-ribbons_6 PF07191.12 KFQ98863.1 - 0.035 14.1 33.8 0.54 10.3 1.2 5.4 2 2 0 3 3 2 0 zinc-ribbons zf-UBP PF02148.19 KFQ98863.1 - 0.12 12.8 41.2 44 4.5 0.1 6.2 1 1 2 3 3 2 0 Zn-finger in ubiquitin-hydrolases and other protein Zn_ribbon_SprT PF17283.2 KFQ98863.1 - 0.15 12.0 42.9 0.082 12.8 9.1 6.3 3 3 0 3 3 2 0 SprT-like zinc ribbon domain BDHCT_assoc PF16204.5 KFQ98863.1 - 0.19 11.4 2.4 1.3 8.7 0.3 2.5 1 1 2 3 3 3 0 BDHCT-box associated domain on Bloom syndrome protein DNA_RNApol_7kD PF03604.13 KFQ98863.1 - 0.31 10.7 24.9 37 4.1 0.1 7.9 8 0 0 8 8 8 0 DNA directed RNA polymerase, 7 kDa subunit BolA PF01722.18 KFQ98863.1 - 0.8 10.0 10.7 4.4 7.7 0.2 3.9 2 2 2 4 4 4 0 BolA-like protein TFIIS_C PF01096.18 KFQ98863.1 - 0.97 9.3 40.3 16 5.4 0.1 7.9 7 1 0 7 7 7 0 Transcription factor S-II (TFIIS) zf-met PF12874.7 KFQ98863.1 - 0.99 9.9 50.3 8.5 6.9 2.8 8.1 8 0 0 8 8 8 0 Zinc-finger of C2H2 type IBR PF01485.21 KFQ98863.1 - 1.2 9.4 41.7 94 3.3 0.3 5.5 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain zf-H2C2_2 PF13465.6 KFQ98864.1 - 1.8e-18 66.0 16.5 1.9e-10 40.7 0.8 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ98864.1 - 6.6e-14 51.5 15.0 3.9e-06 27.0 0.8 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ98864.1 - 4e-08 33.4 12.3 0.0036 18.0 0.7 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFQ98864.1 - 1e-05 25.5 5.9 0.0064 16.6 0.6 2.6 1 1 0 2 2 2 2 Zinc ribbon domain zf-C2H2_6 PF13912.6 KFQ98864.1 - 8.9e-05 22.4 12.6 0.00062 19.7 1.0 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf_UBZ PF18439.1 KFQ98864.1 - 0.00014 21.4 6.5 0.9 9.2 0.4 3.2 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger zf-LYAR PF08790.11 KFQ98864.1 - 0.00017 21.4 5.2 2.9 7.9 0.0 3.3 3 0 0 3 3 3 2 LYAR-type C2HC zinc finger XPA_N PF01286.18 KFQ98864.1 - 0.00047 20.1 4.0 2.1 8.5 0.1 3.2 3 0 0 3 3 3 1 XPA protein N-terminal zinc_ribbon_4 PF13717.6 KFQ98864.1 - 0.00083 19.2 3.5 0.79 9.7 0.3 3.1 1 1 1 2 2 2 2 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KFQ98864.1 - 0.0013 19.5 0.9 0.0048 17.6 0.9 1.8 1 1 0 1 1 1 1 zinc-ribbon family DZR PF12773.7 KFQ98864.1 - 0.002 18.1 2.2 0.0071 16.4 2.2 1.8 1 1 0 1 1 1 1 Double zinc ribbon ADK_lid PF05191.14 KFQ98864.1 - 0.0028 17.6 5.1 0.42 10.6 5.1 2.3 1 1 0 1 1 1 1 Adenylate kinase, active site lid zf-trcl PF13451.6 KFQ98864.1 - 0.0046 16.8 7.5 0.92 9.5 0.2 3.1 3 0 0 3 3 3 2 Probable zinc-ribbon domain zf-AN1 PF01428.16 KFQ98864.1 - 0.005 17.0 7.8 0.86 9.8 0.2 3.1 3 0 0 3 3 3 2 AN1-like Zinc finger LIM PF00412.22 KFQ98864.1 - 0.0076 16.5 2.8 0.11 12.7 0.1 2.6 1 1 1 2 2 2 1 LIM domain zf-C2H2_jaz PF12171.8 KFQ98864.1 - 0.0081 16.4 2.9 1.8 8.9 0.0 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding IBR PF01485.21 KFQ98864.1 - 0.013 15.7 3.1 0.88 9.8 3.1 2.1 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain C1_1 PF00130.22 KFQ98864.1 - 0.02 14.8 3.8 0.18 11.7 2.5 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_11 PF16622.5 KFQ98864.1 - 0.021 14.6 8.1 0.21 11.4 0.2 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type Zn_Tnp_IS1595 PF12760.7 KFQ98864.1 - 0.022 14.7 8.0 0.8 9.7 1.8 2.4 1 1 1 2 2 2 0 Transposase zinc-ribbon domain TFIIS_C PF01096.18 KFQ98864.1 - 0.027 14.3 8.5 1 9.3 0.3 3.1 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) zinc-ribbons_6 PF07191.12 KFQ98864.1 - 0.03 14.3 1.9 0.85 9.6 1.9 2.3 1 1 0 1 1 1 0 zinc-ribbons FYDLN_acid PF09538.10 KFQ98864.1 - 0.037 14.7 1.3 2.9 8.6 0.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-C2H2_8 PF15909.5 KFQ98864.1 - 0.048 14.0 1.2 0.087 13.1 0.2 1.6 1 1 0 1 1 1 0 C2H2-type zinc ribbon HypA PF01155.19 KFQ98864.1 - 0.054 13.5 1.3 0.33 11.0 1.3 2.0 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA YhfH PF14149.6 KFQ98864.1 - 0.055 13.5 7.8 8.6 6.4 0.3 3.2 3 0 0 3 3 3 0 YhfH-like protein zf-Di19 PF05605.12 KFQ98864.1 - 0.071 13.4 1.8 4.4 7.7 0.9 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CpXC PF14353.6 KFQ98864.1 - 0.11 12.5 3.4 2.5 8.1 0.2 2.9 1 1 1 2 2 2 0 CpXC protein zf-RING_7 PF02591.15 KFQ98864.1 - 0.13 12.5 6.9 5.2 7.3 0.1 3.1 3 0 0 3 3 3 0 C4-type zinc ribbon domain DNA_RNApol_7kD PF03604.13 KFQ98864.1 - 0.13 11.9 6.4 2 8.2 0.2 3.1 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2HE PF16278.5 KFQ98864.1 - 0.15 12.5 6.2 0.71 10.4 0.4 2.5 1 1 0 2 2 1 0 C2HE / C2H2 / C2HC zinc-binding finger Zn_ribbon_recom PF13408.6 KFQ98864.1 - 0.22 12.0 6.9 32 5.1 5.8 2.8 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Zn_ribbon_SprT PF17283.2 KFQ98864.1 - 0.24 11.3 4.7 8 6.5 0.2 2.9 2 1 0 2 2 2 0 SprT-like zinc ribbon domain zf-ribbon_3 PF13248.6 KFQ98864.1 - 0.25 10.8 7.6 5.6 6.5 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-Mss51 PF13824.6 KFQ98864.1 - 0.26 11.4 7.3 5.5 7.2 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Mut7-C PF01927.16 KFQ98864.1 - 0.41 10.8 3.1 3.9 7.6 0.1 2.8 1 1 2 3 3 3 0 Mut7-C RNAse domain ZZ PF00569.17 KFQ98864.1 - 0.48 10.3 5.0 0.74 9.7 0.1 2.5 3 0 0 3 3 2 0 Zinc finger, ZZ type zf-Paramyx-P PF13008.7 KFQ98864.1 - 0.61 9.6 5.4 3.2 7.3 0.1 2.6 2 1 0 2 2 2 0 Zinc-binding domain of Paramyxoviridae V protein zf-HIT PF04438.16 KFQ98864.1 - 0.64 9.9 7.0 0.57 10.1 0.4 2.9 3 0 0 3 3 3 0 HIT zinc finger zinc_ribbon_9 PF14369.6 KFQ98864.1 - 0.68 10.2 11.1 2.2 8.6 0.4 3.0 2 1 1 3 3 3 0 zinc-ribbon HalOD2 PF18547.1 KFQ98864.1 - 0.74 9.8 4.9 1.4 8.8 2.7 2.3 2 1 0 2 2 2 0 Halobacterial output domain 2 zf-HYPF PF07503.12 KFQ98864.1 - 0.74 9.6 5.6 28 4.6 0.1 3.2 3 0 0 3 3 3 0 HypF finger zinc_ribbon_5 PF13719.6 KFQ98864.1 - 1.1 9.1 8.2 13 5.6 2.4 3.0 2 1 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 KFQ98864.1 - 1.6 8.7 5.8 5.4 7.0 0.6 2.5 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-dskA_traR PF01258.17 KFQ98864.1 - 2.7 8.0 7.9 18 5.4 0.2 3.2 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger TF_Zn_Ribbon PF08271.12 KFQ98864.1 - 3 7.4 8.0 29 4.3 0.1 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding zinc_ribbon_2 PF13240.6 KFQ98864.1 - 6.2 6.7 14.3 13 5.7 0.4 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-H2C2_2 PF13465.6 KFQ98865.1 - 2.7e-46 154.0 57.2 3.5e-09 36.7 1.1 6.6 7 0 0 7 7 6 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ98865.1 - 3.7e-35 118.4 54.7 9.4e-07 29.0 0.9 7.1 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ98865.1 - 1.4e-20 72.2 49.9 0.0012 19.5 0.8 6.9 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ98865.1 - 3.8e-12 46.2 16.4 0.047 14.0 0.0 5.5 5 0 0 5 5 5 5 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KFQ98865.1 - 9.4e-11 41.6 22.3 0.00017 21.7 1.1 4.3 3 1 1 4 4 4 3 Zinc ribbon domain zf-C2H2_11 PF16622.5 KFQ98865.1 - 2.1e-06 27.4 23.9 0.03 14.1 0.1 5.9 6 0 0 6 6 6 4 zinc-finger C2H2-type zf_UBZ PF18439.1 KFQ98865.1 - 3.8e-06 26.4 23.4 0.56 9.8 0.4 6.1 6 0 0 6 6 6 4 Ubiquitin-Binding Zinc Finger Zn_ribbon_SprT PF17283.2 KFQ98865.1 - 1.9e-05 24.5 28.8 0.0052 16.7 2.4 4.1 3 1 0 3 3 3 3 SprT-like zinc ribbon domain zf-met PF12874.7 KFQ98865.1 - 2.6e-05 24.5 32.3 0.055 13.9 0.2 5.8 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFQ98865.1 - 6.4e-05 23.2 28.4 0.21 11.9 4.6 3.9 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 KFQ98865.1 - 0.00031 20.5 0.3 0.00031 20.5 0.3 3.9 2 1 3 5 5 5 1 GAGA factor zf-C2H2_6 PF13912.6 KFQ98865.1 - 0.00037 20.4 42.2 0.16 12.0 0.3 6.8 7 0 0 7 7 7 4 C2H2-type zinc finger FYDLN_acid PF09538.10 KFQ98865.1 - 0.0017 19.0 16.1 4.8 7.9 0.3 5.7 1 1 5 6 6 6 2 Protein of unknown function (FYDLN_acid) C1_1 PF00130.22 KFQ98865.1 - 0.0021 17.9 27.7 0.038 13.9 5.0 4.4 3 1 1 4 4 4 3 Phorbol esters/diacylglycerol binding domain (C1 domain) LIM PF00412.22 KFQ98865.1 - 0.0025 18.0 22.6 1.4 9.2 4.6 4.6 2 2 3 5 5 5 2 LIM domain zinc_ribbon_15 PF17032.5 KFQ98865.1 - 0.0025 18.5 19.3 0.52 11.1 1.3 3.4 1 1 2 3 3 3 2 zinc-ribbon family zf-AN1 PF01428.16 KFQ98865.1 - 0.0078 16.3 32.9 3.5 7.9 0.2 6.3 6 0 0 6 6 6 1 AN1-like Zinc finger PHD PF00628.29 KFQ98865.1 - 0.025 14.5 1.6 0.025 14.5 1.6 4.3 2 1 1 3 3 2 0 PHD-finger HypA PF01155.19 KFQ98865.1 - 0.026 14.5 17.9 1.3 9.1 2.3 3.5 1 1 3 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zf_RING PF16744.5 KFQ98865.1 - 0.061 13.4 20.4 4.4 7.5 0.3 5.3 1 1 4 5 5 5 0 KIAA1045 RING finger Zn-C2H2_12 PF18112.1 KFQ98865.1 - 0.18 12.3 0.1 0.18 12.3 0.1 5.2 6 0 0 6 6 5 0 Autophagy receptor zinc finger-C2H2 domain Fer4_10 PF13237.6 KFQ98865.1 - 0.27 11.4 19.6 0.36 11.0 6.4 4.9 4 1 1 5 5 5 0 4Fe-4S dicluster domain BolA PF01722.18 KFQ98865.1 - 0.27 11.5 7.8 4.1 7.7 0.1 3.1 2 1 0 3 3 3 0 BolA-like protein XPA_N PF01286.18 KFQ98865.1 - 0.63 10.1 0.1 0.63 10.1 0.1 5.7 6 0 0 6 6 6 0 XPA protein N-terminal DUF3268 PF11672.8 KFQ98865.1 - 0.73 10.2 16.2 0.23 11.8 0.9 3.5 1 1 4 5 5 5 0 zinc-finger-containing domain zinc-ribbons_6 PF07191.12 KFQ98865.1 - 0.77 9.8 24.2 20 5.3 0.2 5.2 1 1 2 3 3 2 0 zinc-ribbons zf-C2HE PF16278.5 KFQ98865.1 - 1.5 9.3 31.9 8.2 7.0 1.5 5.8 1 1 4 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger zf-RING_5 PF14634.6 KFQ98865.1 - 1.6 8.7 26.9 7.2 6.7 6.2 5.2 1 1 2 3 3 2 0 zinc-RING finger domain Baculo_IE-1 PF05290.11 KFQ98865.1 - 2.7 7.9 13.1 4.9 7.1 0.3 3.6 1 1 1 3 3 3 0 Baculovirus immediate-early protein (IE-0) C1_4 PF07975.12 KFQ98865.1 - 3.7 7.8 27.6 13 6.1 3.1 4.8 1 1 5 6 6 6 0 TFIIH C1-like domain CpXC PF14353.6 KFQ98865.1 - 4 7.5 25.1 6.9 6.8 0.1 5.8 1 1 4 6 6 6 0 CpXC protein zf-HIT PF04438.16 KFQ98865.1 - 5 7.1 36.2 2.3 8.2 0.8 6.1 6 0 0 6 6 6 0 HIT zinc finger Mut7-C PF01927.16 KFQ98865.1 - 5.7 7.0 21.6 24 5.0 6.8 4.2 1 1 2 3 3 3 0 Mut7-C RNAse domain HalOD2 PF18547.1 KFQ98865.1 - 7.5 6.5 18.4 40 4.2 0.0 5.1 5 1 0 5 5 5 0 Halobacterial output domain 2 zf-H2C2_2 PF13465.6 KFQ98866.1 - 3.1e-75 245.5 51.0 4e-10 39.7 1.0 9.0 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ98866.1 - 2e-62 204.3 62.1 5.3e-09 36.0 1.2 8.3 9 0 0 9 9 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ98866.1 - 5.3e-40 132.6 50.6 0.00013 22.6 0.4 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ98866.1 - 1e-26 92.6 18.3 0.0016 18.7 0.1 8.1 8 0 0 8 8 8 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFQ98866.1 - 5.4e-19 67.7 46.1 9.7e-05 22.3 0.2 8.3 8 0 0 8 8 8 7 C2H2-type zinc finger zf_UBZ PF18439.1 KFQ98866.1 - 5.3e-17 61.1 26.2 0.082 12.5 0.1 8.1 8 0 0 8 8 8 7 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFQ98866.1 - 7.1e-17 61.2 31.6 5.3e-05 23.2 2.2 6.0 2 1 5 7 7 7 7 Zinc ribbon domain XPA_N PF01286.18 KFQ98866.1 - 1.5e-12 47.3 28.5 0.55 10.3 0.1 8.1 8 0 0 8 8 8 4 XPA protein N-terminal zf-LYAR PF08790.11 KFQ98866.1 - 1.3e-10 41.0 28.9 0.081 12.8 0.1 8.1 8 0 0 8 8 8 4 LYAR-type C2HC zinc finger zf-met PF12874.7 KFQ98866.1 - 1.5e-10 41.1 40.4 0.18 12.2 0.2 8.2 8 0 0 8 8 8 3 Zinc-finger of C2H2 type C1_4 PF07975.12 KFQ98866.1 - 5.9e-10 39.2 23.2 0.055 13.7 0.6 6.0 1 1 3 6 6 6 5 TFIIH C1-like domain CpXC PF14353.6 KFQ98866.1 - 1.2e-09 38.2 21.6 0.69 10.0 1.0 7.8 4 3 1 6 6 6 3 CpXC protein zf-C2H2_8 PF15909.5 KFQ98866.1 - 1.6e-09 37.9 20.9 0.0037 17.5 2.2 4.6 1 1 4 5 5 5 5 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 KFQ98866.1 - 2.1e-09 36.9 30.7 0.11 12.2 0.1 8.2 8 0 0 8 8 8 3 zinc-finger C2H2-type DZR PF12773.7 KFQ98866.1 - 4.9e-09 36.1 25.6 0.025 14.6 1.3 4.9 1 1 0 2 2 2 1 Double zinc ribbon FYDLN_acid PF09538.10 KFQ98866.1 - 7.9e-08 32.9 17.6 2.2 9.0 0.8 7.4 1 1 7 8 8 8 1 Protein of unknown function (FYDLN_acid) zf-trcl PF13451.6 KFQ98866.1 - 1.2e-07 31.5 23.2 3.3 7.7 0.1 8.0 8 0 0 8 8 8 0 Probable zinc-ribbon domain zinc_ribbon_15 PF17032.5 KFQ98866.1 - 1.2e-07 32.4 22.0 0.095 13.5 0.8 4.2 1 1 3 4 4 4 4 zinc-ribbon family Zn_ribbon_SprT PF17283.2 KFQ98866.1 - 1.4e-07 31.2 29.1 0.6 10.1 0.7 7.3 6 2 0 6 6 6 2 SprT-like zinc ribbon domain C1_1 PF00130.22 KFQ98866.1 - 3.5e-07 30.0 18.0 0.3 11.0 0.6 6.2 1 1 7 8 8 8 5 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-AN1 PF01428.16 KFQ98866.1 - 2.4e-06 27.6 33.3 3.9 7.7 0.1 8.2 7 1 1 8 8 8 0 AN1-like Zinc finger HypA PF01155.19 KFQ98866.1 - 4.3e-06 26.7 21.0 0.16 12.0 0.5 4.5 1 1 3 4 4 4 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Di19 PF05605.12 KFQ98866.1 - 4.3e-06 26.9 27.3 0.0049 17.1 1.5 5.9 1 1 5 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding DUF3268 PF11672.8 KFQ98866.1 - 5.8e-06 26.6 18.4 0.12 12.7 0.3 4.4 1 1 0 4 4 4 2 zinc-finger-containing domain DNA_RNApol_7kD PF03604.13 KFQ98866.1 - 8.7e-06 25.3 24.5 3.8 7.3 0.1 8.1 8 0 0 8 8 8 0 DNA directed RNA polymerase, 7 kDa subunit ADK_lid PF05191.14 KFQ98866.1 - 1e-05 25.4 26.4 1.4 9.0 0.8 6.4 4 2 3 7 7 7 2 Adenylate kinase, active site lid YhfH PF14149.6 KFQ98866.1 - 1.4e-05 24.9 24.4 6.6 6.8 0.2 7.8 8 0 0 8 8 8 0 YhfH-like protein zinc_ribbon_4 PF13717.6 KFQ98866.1 - 2.5e-05 24.1 26.9 0.88 9.5 2.3 7.6 6 1 1 7 7 7 2 zinc-ribbon domain zf-HIT PF04438.16 KFQ98866.1 - 3.3e-05 23.6 36.7 3 7.8 0.3 8.1 8 0 0 8 8 8 0 HIT zinc finger zf-C2HC_2 PF13913.6 KFQ98866.1 - 9.4e-05 22.2 32.8 0.018 14.9 0.1 7.4 8 0 0 8 8 8 2 zinc-finger of a C2HC-type TFIIS_C PF01096.18 KFQ98866.1 - 0.00029 20.6 33.3 6.9 6.6 0.1 8.1 8 0 0 8 8 8 0 Transcription factor S-II (TFIIS) zf_C2H2_ZHX PF18387.1 KFQ98866.1 - 0.00049 19.7 25.8 2.1 8.0 0.5 7.5 1 1 7 8 8 8 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-Mss51 PF13824.6 KFQ98866.1 - 0.00058 19.9 42.1 0.31 11.2 0.3 7.5 1 1 5 6 6 6 2 Zinc-finger of mitochondrial splicing suppressor 51 zinc_ribbon_5 PF13719.6 KFQ98866.1 - 0.00063 19.5 24.7 3.6 7.4 0.0 7.5 7 1 1 8 8 8 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 KFQ98866.1 - 0.00082 19.3 37.9 0.016 15.2 3.8 5.6 4 3 1 5 5 5 2 Transposase zinc-ribbon domain zinc-ribbons_6 PF07191.12 KFQ98866.1 - 0.00093 19.1 25.9 90 3.2 9.6 6.2 1 1 1 2 2 2 0 zinc-ribbons zinc_ribbon_9 PF14369.6 KFQ98866.1 - 0.0011 19.2 24.6 1.4 9.2 0.1 7.4 8 0 0 8 8 8 1 zinc-ribbon Zn_ribbon_recom PF13408.6 KFQ98866.1 - 0.0012 19.3 28.6 5.9 7.5 0.7 7.2 1 1 5 6 6 6 0 Recombinase zinc beta ribbon domain zf-RING_7 PF02591.15 KFQ98866.1 - 0.0021 18.2 27.4 0.46 10.7 0.1 7.7 8 0 0 8 8 8 1 C4-type zinc ribbon domain IBR PF01485.21 KFQ98866.1 - 0.0028 17.8 33.1 0.087 13.1 1.7 5.3 1 1 3 4 4 4 1 IBR domain, a half RING-finger domain LIM PF00412.22 KFQ98866.1 - 0.014 15.6 25.1 5.5 7.3 1.2 6.8 1 1 5 7 7 7 0 LIM domain DUF2072 PF09845.9 KFQ98866.1 - 0.02 15.1 27.8 3.8 7.8 2.2 7.0 5 2 2 7 7 7 0 Zn-ribbon containing protein TF_Zn_Ribbon PF08271.12 KFQ98866.1 - 0.022 14.3 32.9 1.8 8.1 0.3 7.4 7 1 0 7 7 7 0 TFIIB zinc-binding FdhE PF04216.12 KFQ98866.1 - 0.029 14.3 0.6 0.029 14.3 0.6 3.9 1 1 2 4 4 3 0 Protein involved in formate dehydrogenase formation YacG PF03884.14 KFQ98866.1 - 0.047 13.4 19.3 18 5.2 0.0 6.6 7 1 1 8 8 7 0 DNA gyrase inhibitor YacG zf-C2H2_3rep PF18868.1 KFQ98866.1 - 0.086 13.5 16.8 19 6.0 3.7 5.8 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-BED PF02892.15 KFQ98866.1 - 0.1 12.6 37.4 0.68 10.0 1.1 7.6 1 1 5 6 6 6 0 BED zinc finger zf-Paramyx-P PF13008.7 KFQ98866.1 - 0.14 11.7 29.8 14 5.2 0.2 7.8 8 0 0 8 8 8 0 Zinc-binding domain of Paramyxoviridae V protein GAGA PF09237.11 KFQ98866.1 - 0.18 11.6 15.4 2 8.3 0.0 5.4 1 1 5 6 6 6 0 GAGA factor Yippee-Mis18 PF03226.14 KFQ98866.1 - 0.34 11.2 20.2 14 6.0 3.1 5.8 3 2 1 4 4 4 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C2H2_9 PF16293.5 KFQ98866.1 - 0.4 10.6 8.2 20 5.1 0.1 4.6 4 1 1 5 5 4 0 C2H2 type zinc-finger (1 copy) DUF2256 PF10013.9 KFQ98866.1 - 0.4 10.8 22.0 14 5.9 0.1 7.5 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) TRAF6_Z2 PF18048.1 KFQ98866.1 - 0.44 10.7 7.6 24 5.1 0.1 4.9 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 Rad50_zn_hook PF04423.14 KFQ98866.1 - 0.48 10.3 12.2 13 5.7 0.1 4.9 3 1 1 4 4 4 0 Rad50 zinc hook motif zf-ribbon_3 PF13248.6 KFQ98866.1 - 0.58 9.6 34.2 2.2 7.8 0.3 7.1 8 0 0 8 8 7 0 zinc-ribbon domain zf-C2HE PF16278.5 KFQ98866.1 - 0.84 10.1 35.7 25 5.4 0.4 7.9 1 1 7 8 8 8 0 C2HE / C2H2 / C2HC zinc-binding finger Cys_rich_CPXG PF14255.6 KFQ98866.1 - 1.1 9.2 12.6 20 5.2 0.1 5.3 6 0 0 6 6 4 0 Cysteine-rich CPXCG PHF5 PF03660.14 KFQ98866.1 - 1.3 9.3 14.1 3.1 8.1 0.5 4.0 1 1 3 4 4 4 0 PHF5-like protein TerY_C PF15616.6 KFQ98866.1 - 1.6 8.8 13.7 4 7.6 0.2 3.5 1 1 2 4 4 4 0 TerY-C metal binding domain NuA4 PF09340.10 KFQ98866.1 - 2.2 8.2 7.2 10 6.1 0.3 4.0 3 2 0 3 3 3 0 Histone acetyltransferase subunit NuA4 zinc_ribbon_10 PF10058.9 KFQ98866.1 - 2.3 8.0 27.3 34 4.3 0.1 7.2 6 2 1 7 7 7 0 Predicted integral membrane zinc-ribbon metal-binding protein HNH PF01844.23 KFQ98866.1 - 5.4 7.3 30.9 21 5.4 0.3 7.7 8 0 0 8 8 8 0 HNH endonuclease DUF4379 PF14311.6 KFQ98866.1 - 8.8 6.8 30.4 1.8 9.0 1.5 5.4 2 2 5 7 7 7 0 Probable Zinc-ribbon domain zf_ZIC PF18366.1 KFQ98866.1 - 10 6.4 19.6 42 4.4 0.2 6.7 1 1 7 8 8 8 0 Zic proteins zinc finger domain Se-cys_synth_N PF12390.8 KFQ98867.1 - 1.5 9.1 13.3 1.5e+02 2.7 7.9 4.2 2 2 0 2 2 2 0 Selenocysteine synthase N terminal zf-C2H2 PF00096.26 KFQ98868.1 - 1e-50 167.4 55.1 9.1e-08 32.2 0.7 8.3 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ98868.1 - 6.2e-47 156.0 46.5 4.7e-07 29.9 2.6 8.3 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ98868.1 - 1.3e-33 112.7 50.1 0.00011 22.7 0.5 8.2 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ98868.1 - 1.3e-21 76.3 19.1 0.0019 18.5 0.2 8.1 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFQ98868.1 - 7.8e-11 41.4 22.3 0.93 9.1 0.2 8.1 8 0 0 8 8 8 4 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFQ98868.1 - 1.6e-10 40.9 28.8 0.0076 16.3 4.4 6.3 2 1 6 8 8 8 5 Zinc ribbon domain zf-C2H2_6 PF13912.6 KFQ98868.1 - 3.4e-10 39.7 38.7 0.058 13.4 0.8 8.9 8 1 0 8 8 8 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFQ98868.1 - 1e-08 34.7 31.8 0.22 11.3 0.7 8.2 8 0 0 8 8 8 4 zinc-finger C2H2-type XPA_N PF01286.18 KFQ98868.1 - 4e-07 29.9 21.7 2.4 8.3 0.0 7.3 8 0 0 8 8 7 4 XPA protein N-terminal zinc_ribbon_15 PF17032.5 KFQ98868.1 - 7.3e-07 29.9 19.7 0.093 13.5 0.6 4.6 1 1 4 5 5 5 4 zinc-ribbon family zf-met PF12874.7 KFQ98868.1 - 1.3e-06 28.6 33.1 0.2 12.1 0.3 7.9 8 0 0 8 8 8 3 Zinc-finger of C2H2 type CpXC PF14353.6 KFQ98868.1 - 2.4e-06 27.6 19.3 0.51 10.4 0.4 6.5 3 2 2 6 6 6 2 CpXC protein DZR PF12773.7 KFQ98868.1 - 2.9e-06 27.2 24.7 0.0077 16.2 6.2 4.7 2 2 2 4 4 4 2 Double zinc ribbon DUF3268 PF11672.8 KFQ98868.1 - 6.8e-06 26.4 13.1 0.028 14.7 0.6 4.2 3 1 0 4 4 4 2 zinc-finger-containing domain ADK_lid PF05191.14 KFQ98868.1 - 3.4e-05 23.7 20.5 0.016 15.2 3.3 6.0 4 3 2 6 6 6 2 Adenylate kinase, active site lid Zn_ribbon_SprT PF17283.2 KFQ98868.1 - 7.5e-05 22.6 35.1 0.042 13.8 6.0 6.3 4 2 1 5 5 5 3 SprT-like zinc ribbon domain zf-LYAR PF08790.11 KFQ98868.1 - 0.0001 22.1 26.2 0.12 12.3 0.2 8.2 8 0 0 8 8 8 1 LYAR-type C2HC zinc finger C1_1 PF00130.22 KFQ98868.1 - 0.00011 22.0 20.7 0.42 10.5 2.3 6.0 1 1 7 8 8 8 4 Phorbol esters/diacylglycerol binding domain (C1 domain) Yippee-Mis18 PF03226.14 KFQ98868.1 - 0.00018 21.7 9.9 0.21 11.8 0.1 4.7 5 0 0 5 5 5 2 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C2HC_2 PF13913.6 KFQ98868.1 - 0.00018 21.3 32.4 0.85 9.6 0.1 7.4 7 0 0 7 7 7 1 zinc-finger of a C2HC-type zf-Di19 PF05605.12 KFQ98868.1 - 0.00023 21.4 27.4 0.13 12.6 0.6 5.3 1 1 4 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.16 KFQ98868.1 - 0.00052 20.1 33.2 3.3 8.0 1.1 7.8 6 2 2 8 8 7 1 AN1-like Zinc finger TFIIS_C PF01096.18 KFQ98868.1 - 0.00057 19.7 20.9 6.9 6.6 0.1 7.2 7 0 0 7 7 7 0 Transcription factor S-II (TFIIS) HypA PF01155.19 KFQ98868.1 - 0.00093 19.2 16.6 0.26 11.3 1.0 4.5 1 1 3 4 4 4 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FYDLN_acid PF09538.10 KFQ98868.1 - 0.002 18.8 18.5 4.5 8.0 0.1 6.6 1 1 3 5 5 5 0 Protein of unknown function (FYDLN_acid) DNA_RNApol_7kD PF03604.13 KFQ98868.1 - 0.0027 17.3 23.3 16 5.3 0.2 7.3 7 0 0 7 7 7 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_4 PF13717.6 KFQ98868.1 - 0.0056 16.6 1.0 0.0056 16.6 1.0 6.3 6 2 0 6 6 4 1 zinc-ribbon domain CxC7 PF18866.1 KFQ98868.1 - 0.0082 16.3 16.8 1.8 8.7 0.1 6.1 4 2 3 7 7 6 1 CxC7 like cysteine cluster associated with KDZ transposases zinc_ribbon_5 PF13719.6 KFQ98868.1 - 0.011 15.5 18.2 2.4 8.0 0.1 6.2 6 0 0 6 6 6 0 zinc-ribbon domain DUF2256 PF10013.9 KFQ98868.1 - 0.011 15.8 22.7 13 6.0 0.1 7.6 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-RING_7 PF02591.15 KFQ98868.1 - 0.012 15.8 21.3 7.3 6.9 0.2 6.4 6 0 0 6 6 6 0 C4-type zinc ribbon domain zf-HIT PF04438.16 KFQ98868.1 - 0.015 15.2 32.9 4.6 7.2 0.1 7.1 8 0 0 8 8 7 0 HIT zinc finger zf-trcl PF13451.6 KFQ98868.1 - 0.016 15.1 24.3 19 5.3 0.2 7.1 7 0 0 7 7 7 0 Probable zinc-ribbon domain zinc-ribbons_6 PF07191.12 KFQ98868.1 - 0.023 14.7 24.6 2.2 8.3 1.3 5.4 2 2 2 4 4 4 0 zinc-ribbons Zn_Tnp_IS1595 PF12760.7 KFQ98868.1 - 0.024 14.6 29.6 0.037 14.0 2.4 4.8 4 1 0 4 4 4 0 Transposase zinc-ribbon domain zinc_ribbon_10 PF10058.9 KFQ98868.1 - 0.029 14.1 16.8 22 4.9 0.0 6.5 6 1 0 6 6 6 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn_ribbon_recom PF13408.6 KFQ98868.1 - 0.07 13.7 30.6 1.2 9.7 0.5 5.3 2 1 4 6 6 5 0 Recombinase zinc beta ribbon domain C1_4 PF07975.12 KFQ98868.1 - 0.081 13.2 29.5 2.1 8.6 0.4 6.1 2 2 5 7 7 7 0 TFIIH C1-like domain zf-H2C2_5 PF13909.6 KFQ98868.1 - 0.12 12.2 0.6 0.12 12.2 0.6 9.4 8 4 0 8 8 6 0 C2H2-type zinc-finger domain Zn-C2H2_12 PF18112.1 KFQ98868.1 - 0.19 12.2 8.8 8.3 7.0 0.5 5.0 5 0 0 5 5 3 0 Autophagy receptor zinc finger-C2H2 domain LIM PF00412.22 KFQ98868.1 - 0.27 11.5 21.8 13 6.1 0.9 5.8 1 1 5 6 6 6 0 LIM domain zf-C2HE PF16278.5 KFQ98868.1 - 0.45 11.0 33.0 9.5 6.8 0.1 7.0 2 2 3 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger Prok-RING_1 PF14446.6 KFQ98868.1 - 1 9.4 20.2 10 6.1 0.0 6.8 7 1 1 8 8 7 0 Prokaryotic RING finger family 1 zinc_ribbon_9 PF14369.6 KFQ98868.1 - 2.1 8.7 29.2 1.4 9.2 0.2 7.1 7 1 1 8 8 7 0 zinc-ribbon zf-MYST PF17772.1 KFQ98868.1 - 3.2 7.4 12.6 19 5.0 0.0 5.1 3 2 3 6 6 6 0 MYST family zinc finger domain FOXP-CC PF16159.5 KFQ98868.1 - 3.4 8.4 19.6 21 5.8 0.3 6.3 3 1 4 7 7 7 0 FOXP coiled-coil domain TF_Zn_Ribbon PF08271.12 KFQ98868.1 - 5.7 6.5 26.7 4.5 6.9 3.7 5.6 5 2 0 5 5 5 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 KFQ98868.1 - 5.8 6.5 26.7 13 5.3 0.2 6.7 7 0 0 7 7 7 0 zinc-ribbon domain HNH PF01844.23 KFQ98868.1 - 9.1 6.5 29.9 0.11 12.7 1.5 6.5 7 1 1 8 8 7 0 HNH endonuclease DUF2072 PF09845.9 KFQ98868.1 - 9.7 6.5 22.0 11 6.2 0.1 6.3 6 1 1 8 8 8 0 Zn-ribbon containing protein zf-H2C2_2 PF13465.6 KFQ98870.1 - 9.9e-58 190.1 34.4 1.2e-10 41.4 0.1 6.9 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ98870.1 - 6.1e-45 149.2 41.5 4.9e-09 36.2 0.6 7.1 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ98870.1 - 1.2e-26 91.1 40.1 6.9e-05 23.3 0.6 7.0 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ98870.1 - 1.6e-14 53.7 5.3 0.027 14.8 0.0 6.2 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFQ98870.1 - 4.9e-12 45.2 21.0 0.02 14.5 0.1 6.4 5 1 0 6 6 6 4 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFQ98870.1 - 3.7e-11 43.0 20.2 0.0004 20.4 0.9 4.3 1 1 4 5 5 5 5 Zinc ribbon domain zf-C2H2_6 PF13912.6 KFQ98870.1 - 7.7e-11 41.7 29.9 0.012 15.6 0.3 6.6 6 0 0 6 6 6 4 C2H2-type zinc finger DZR PF12773.7 KFQ98870.1 - 1.1e-09 38.1 15.4 0.0007 19.6 2.1 3.4 1 1 1 2 2 2 2 Double zinc ribbon zf-C2HC_2 PF13913.6 KFQ98870.1 - 2.9e-07 30.2 20.2 0.01 15.7 0.1 7.2 7 0 0 7 7 7 1 zinc-finger of a C2HC-type XPA_N PF01286.18 KFQ98870.1 - 7e-07 29.2 17.4 2.5 8.2 0.4 6.2 6 0 0 6 6 6 1 XPA protein N-terminal zf-Di19 PF05605.12 KFQ98870.1 - 9.8e-07 29.0 21.8 0.0049 17.1 2.9 4.7 1 1 4 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KFQ98870.1 - 1.2e-06 28.6 25.7 0.023 15.1 0.3 6.2 6 0 0 6 6 6 1 Zinc-finger of C2H2 type YhfH PF14149.6 KFQ98870.1 - 1.5e-06 28.0 12.6 5.1 7.2 0.0 6.1 6 0 0 6 6 6 0 YhfH-like protein zf-trcl PF13451.6 KFQ98870.1 - 2.2e-06 27.4 12.3 2.8 7.9 0.1 6.1 6 0 0 6 6 6 0 Probable zinc-ribbon domain zf-ribbon_3 PF13248.6 KFQ98870.1 - 2.6e-06 26.6 23.9 0.14 11.6 0.4 6.1 6 0 0 6 6 6 2 zinc-ribbon domain zinc_ribbon_9 PF14369.6 KFQ98870.1 - 2.7e-06 27.5 21.2 0.21 11.9 0.5 5.9 6 0 0 6 6 6 2 zinc-ribbon zinc_ribbon_15 PF17032.5 KFQ98870.1 - 3.5e-06 27.7 10.9 0.14 12.9 0.7 3.1 2 1 1 3 3 3 2 zinc-ribbon family FYDLN_acid PF09538.10 KFQ98870.1 - 9e-06 26.3 13.4 3.9 8.2 0.1 5.8 1 1 3 5 5 5 0 Protein of unknown function (FYDLN_acid) CpXC PF14353.6 KFQ98870.1 - 1e-05 25.6 16.4 0.74 9.9 0.1 5.7 1 1 5 6 6 6 1 CpXC protein HypA PF01155.19 KFQ98870.1 - 2.9e-05 24.1 11.6 0.31 11.1 0.9 3.4 1 1 2 3 3 3 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_4 PF07975.12 KFQ98870.1 - 3.7e-05 23.9 17.4 2.1 8.6 3.4 4.8 1 1 1 4 4 4 1 TFIIH C1-like domain DUF3268 PF11672.8 KFQ98870.1 - 7.9e-05 23.0 11.9 0.37 11.1 0.3 3.3 1 1 2 3 3 3 2 zinc-finger-containing domain GAGA PF09237.11 KFQ98870.1 - 9.1e-05 22.2 14.8 0.029 14.2 0.5 4.5 1 1 2 5 5 4 2 GAGA factor Prok-RING_1 PF14446.6 KFQ98870.1 - 0.00015 21.6 14.7 14 5.7 0.0 6.0 5 1 0 5 5 5 0 Prokaryotic RING finger family 1 zf-LYAR PF08790.11 KFQ98870.1 - 0.00029 20.7 22.1 0.066 13.1 0.3 6.1 6 0 0 6 6 6 2 LYAR-type C2HC zinc finger DNA_RNApol_7kD PF03604.13 KFQ98870.1 - 0.00047 19.8 18.5 1.1 8.9 0.1 6.2 6 0 0 6 6 6 1 DNA directed RNA polymerase, 7 kDa subunit zinc-ribbons_6 PF07191.12 KFQ98870.1 - 0.0005 20.0 15.9 2.4 8.2 0.5 4.9 1 1 2 3 3 3 1 zinc-ribbons zf-AN1 PF01428.16 KFQ98870.1 - 0.0012 18.9 31.2 1.2 9.4 0.6 6.3 4 2 2 6 6 6 1 AN1-like Zinc finger ADK_lid PF05191.14 KFQ98870.1 - 0.0013 18.7 15.4 0.21 11.6 0.4 5.8 3 3 4 7 7 7 2 Adenylate kinase, active site lid zf-C2H2_11 PF16622.5 KFQ98870.1 - 0.0016 18.2 30.9 0.51 10.2 0.4 6.8 7 0 0 7 7 7 2 zinc-finger C2H2-type zf-HIT PF04438.16 KFQ98870.1 - 0.0025 17.6 25.6 2.5 8.1 0.3 6.1 6 0 0 6 6 6 1 HIT zinc finger LIM PF00412.22 KFQ98870.1 - 0.0025 18.0 15.9 2.2 8.5 2.9 4.9 1 1 4 5 5 5 1 LIM domain DUF2256 PF10013.9 KFQ98870.1 - 0.0028 17.7 12.5 21 5.3 0.0 6.0 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) TFIIS_C PF01096.18 KFQ98870.1 - 0.0029 17.4 18.3 13 5.8 0.1 6.1 6 0 0 6 6 6 0 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.7 KFQ98870.1 - 0.0067 16.4 27.0 1.5 8.8 4.0 4.8 3 2 2 5 5 5 2 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.6 KFQ98870.1 - 0.012 15.5 22.0 12 5.9 0.2 6.5 6 1 0 6 6 6 0 zinc-ribbon domain Zf_RING PF16744.5 KFQ98870.1 - 0.04 14.0 13.7 1.6 8.9 0.1 5.5 1 1 5 6 6 6 0 KIAA1045 RING finger YacG PF03884.14 KFQ98870.1 - 0.045 13.5 11.9 7.9 6.3 0.1 5.0 6 0 0 6 6 5 0 DNA gyrase inhibitor YacG BolA PF01722.18 KFQ98870.1 - 0.047 14.0 4.6 0.064 13.5 0.6 2.9 2 1 1 3 3 3 0 BolA-like protein Zn-C2H2_12 PF18112.1 KFQ98870.1 - 0.078 13.5 12.6 6.7 7.3 0.0 4.8 5 0 0 5 5 4 0 Autophagy receptor zinc finger-C2H2 domain Cript PF10235.9 KFQ98870.1 - 0.078 13.6 13.4 24 5.6 1.8 5.3 4 1 1 5 5 4 0 Microtubule-associated protein CRIPT Zn_ribbon_SprT PF17283.2 KFQ98870.1 - 0.085 12.8 29.0 0.96 9.4 2.2 5.6 2 2 1 4 4 4 0 SprT-like zinc ribbon domain Ogr_Delta PF04606.12 KFQ98870.1 - 0.11 12.4 20.8 1.8 8.6 0.9 4.9 4 1 0 4 4 4 0 Ogr/Delta-like zinc finger BDHCT_assoc PF16204.5 KFQ98870.1 - 0.12 12.1 0.8 2.1 8.0 0.1 2.3 1 1 1 2 2 2 0 BDHCT-box associated domain on Bloom syndrome protein Zn_ribbon_recom PF13408.6 KFQ98870.1 - 0.12 12.9 21.7 16 6.1 3.7 5.2 1 1 5 6 6 6 0 Recombinase zinc beta ribbon domain zf-C2H2_9 PF16293.5 KFQ98870.1 - 0.16 11.8 7.1 49 3.9 0.1 4.2 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) FYVE PF01363.21 KFQ98870.1 - 0.21 11.8 21.6 30 4.9 6.9 4.2 1 1 2 3 3 3 0 FYVE zinc finger zf-Mss51 PF13824.6 KFQ98870.1 - 0.27 11.4 30.8 12 6.1 0.6 5.9 2 1 1 4 4 4 0 Zinc-finger of mitochondrial splicing suppressor 51 HNH PF01844.23 KFQ98870.1 - 0.27 11.4 24.4 1.6 9.0 0.6 6.2 6 1 0 6 6 6 0 HNH endonuclease Ribosomal_L37ae PF01780.19 KFQ98870.1 - 0.3 11.2 20.1 25 5.0 0.1 5.9 1 1 4 6 6 6 0 Ribosomal L37ae protein family Siva PF05458.12 KFQ98870.1 - 0.36 10.5 9.2 1 9.0 1.7 2.9 1 1 1 3 3 3 0 Cd27 binding protein (Siva) zf_C2H2_ZHX PF18387.1 KFQ98870.1 - 0.8 9.4 21.5 6.5 6.5 0.2 5.6 1 1 5 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF899 PF05988.12 KFQ98870.1 - 1.7 8.1 4.1 16 4.9 0.1 3.0 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF899) zf-C2HE PF16278.5 KFQ98870.1 - 2.2 8.8 19.2 1e+02 3.4 0.3 5.9 2 1 2 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger IBR PF01485.21 KFQ98870.1 - 2.5 8.4 22.8 1.9 8.8 3.5 4.2 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain DUF2072 PF09845.9 KFQ98870.1 - 2.6 8.3 20.1 5.8 7.2 2.1 4.9 3 2 2 5 5 5 0 Zn-ribbon containing protein Yippee-Mis18 PF03226.14 KFQ98870.1 - 2.7 8.2 11.9 31 4.9 6.3 4.0 3 1 1 4 4 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF3797 PF12677.7 KFQ98870.1 - 3.5 7.6 14.7 36 4.3 0.0 5.3 5 1 1 6 6 6 0 Domain of unknown function (DUF3797) zinc_ribbon_5 PF13719.6 KFQ98870.1 - 3.6 7.4 22.9 21 5.0 0.0 5.9 6 1 0 6 6 5 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 KFQ98870.1 - 3.8 7.1 22.7 6.3 6.4 0.1 5.6 6 0 0 6 6 6 0 TFIIB zinc-binding FdhE PF04216.12 KFQ98870.1 - 4.4 7.1 16.5 21 4.9 8.7 3.7 1 1 2 3 3 3 0 Protein involved in formate dehydrogenase formation FOXP-CC PF16159.5 KFQ98870.1 - 4.9 7.9 7.6 58 4.4 0.1 4.1 3 2 1 4 4 4 0 FOXP coiled-coil domain zf_ZIC PF18366.1 KFQ98870.1 - 4.9 7.3 13.0 4.4 7.5 0.1 4.9 3 1 3 6 6 4 0 Zic proteins zinc finger domain zf-RING_5 PF14634.6 KFQ98870.1 - 5 7.2 22.7 19 5.3 0.9 5.4 2 2 2 4 4 3 0 zinc-RING finger domain DUF4796 PF16044.5 KFQ98870.1 - 7.1 6.2 12.1 14 5.3 0.1 4.4 1 1 4 5 5 5 0 Domain of unknown function (DUF4796) zf-ISL3 PF14690.6 KFQ98870.1 - 7.6 7.3 22.0 3.7 8.3 0.5 5.9 6 0 0 6 6 6 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Rad50_zn_hook PF04423.14 KFQ98870.1 - 9.4 6.2 9.1 70 3.4 0.1 4.1 4 0 0 4 4 4 0 Rad50 zinc hook motif zf-C2H2 PF00096.26 KFQ98872.1 - 1e-15 57.2 9.8 2.7e-08 33.8 0.5 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ98872.1 - 2.4e-14 53.0 14.8 1.5e-11 44.2 0.5 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ98872.1 - 1.9e-09 37.6 8.7 1.3e-05 25.6 0.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFQ98872.1 - 9.7e-07 28.6 7.0 1.7e-05 24.7 0.3 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFQ98872.1 - 0.00022 20.9 9.2 0.0095 15.7 4.2 2.1 2 0 0 2 2 2 2 zinc-finger C2H2-type zf_UBZ PF18439.1 KFQ98872.1 - 0.00024 20.6 3.5 0.028 14.0 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFQ98872.1 - 0.00038 20.5 2.1 0.00071 19.6 2.1 1.5 1 1 0 1 1 1 1 Zinc ribbon domain C1_4 PF07975.12 KFQ98872.1 - 0.0013 18.9 0.2 0.012 15.8 0.2 1.9 1 1 0 1 1 1 1 TFIIH C1-like domain zf-H2C2_5 PF13909.6 KFQ98872.1 - 0.0023 17.6 12.6 0.088 12.6 2.6 3.5 3 1 0 3 3 3 2 C2H2-type zinc-finger domain zf-ribbon_3 PF13248.6 KFQ98872.1 - 0.0073 15.7 4.4 0.14 11.6 0.1 2.2 2 0 0 2 2 2 1 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 KFQ98872.1 - 0.0092 15.9 3.1 0.021 14.7 3.1 1.6 1 1 0 1 1 1 1 SprT-like zinc ribbon domain zf-C2H2_jaz PF12171.8 KFQ98872.1 - 0.0097 16.2 1.5 0.019 15.3 0.0 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding DZR PF12773.7 KFQ98872.1 - 0.0099 15.9 2.0 0.013 15.5 2.0 1.2 1 0 0 1 1 1 1 Double zinc ribbon CpXC PF14353.6 KFQ98872.1 - 0.019 15.0 0.6 0.34 11.0 0.1 2.0 1 1 1 2 2 2 0 CpXC protein XPA_N PF01286.18 KFQ98872.1 - 0.048 13.7 5.4 0.42 10.7 0.2 2.2 2 0 0 2 2 2 0 XPA protein N-terminal Fer4_10 PF13237.6 KFQ98872.1 - 0.052 13.7 1.8 0.17 12.0 1.8 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain zf-Di19 PF05605.12 KFQ98872.1 - 0.069 13.4 1.2 0.29 11.5 0.1 1.8 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF3268 PF11672.8 KFQ98872.1 - 0.079 13.3 0.6 0.082 13.2 0.6 1.1 1 0 0 1 1 1 0 zinc-finger-containing domain zf-RING_7 PF02591.15 KFQ98872.1 - 0.1 12.8 0.2 0.1 12.8 0.2 2.1 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf-met PF12874.7 KFQ98872.1 - 0.15 12.5 5.4 1.7 9.1 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 KFQ98872.1 - 0.17 11.6 1.3 1.3 8.7 0.0 2.0 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain YhfH PF14149.6 KFQ98872.1 - 0.17 11.9 4.6 1.2 9.2 0.1 2.2 2 0 0 2 2 2 0 YhfH-like protein TF_Zn_Ribbon PF08271.12 KFQ98872.1 - 0.19 11.3 3.3 0.36 10.4 0.0 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding HypA PF01155.19 KFQ98872.1 - 0.3 11.1 2.1 0.35 10.9 2.1 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 KFQ98872.1 - 0.42 10.6 4.4 1.3 9.0 0.2 2.1 1 1 0 2 2 2 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.13 KFQ98872.1 - 1.4 8.7 5.7 43 3.9 5.8 2.2 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Fer4_2 PF12797.7 KFQ98872.1 - 1.8 8.8 5.8 6.6 7.0 1.7 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain zinc_ribbon_5 PF13719.6 KFQ98872.1 - 4 7.3 5.9 3.2 7.6 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Collagen PF01391.18 KFQ98891.1 - 2.4e-71 235.4 217.1 8.5e-08 31.8 17.4 10.2 1 1 10 11 11 11 11 Collagen triple helix repeat (20 copies) zf-H2C2_2 PF13465.6 KFQ98892.1 - 4.3e-51 169.2 44.7 7.8e-08 32.4 0.2 9.0 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ98892.1 - 1.5e-44 148.0 38.5 8.2e-06 26.0 0.4 8.2 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ98892.1 - 4.1e-31 105.0 37.2 2.9e-05 24.5 0.6 8.2 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ98892.1 - 8.1e-23 80.2 0.3 0.0023 18.2 0.0 8.0 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFQ98892.1 - 1.1e-09 38.4 20.3 0.047 14.1 0.0 7.6 8 0 0 8 8 8 3 Zinc-finger of C2H2 type zf_UBZ PF18439.1 KFQ98892.1 - 5.6e-08 32.2 22.0 0.33 10.6 0.1 7.5 8 0 0 8 8 8 3 Ubiquitin-Binding Zinc Finger zf-LYAR PF08790.11 KFQ98892.1 - 2.7e-07 30.4 14.9 0.21 11.5 0.0 6.8 8 0 0 8 8 7 2 LYAR-type C2HC zinc finger zinc_ribbon_15 PF17032.5 KFQ98892.1 - 4.9e-05 24.0 11.1 0.7 10.7 0.1 4.2 2 1 1 4 4 4 1 zinc-ribbon family Zn_ribbon_SprT PF17283.2 KFQ98892.1 - 0.00011 22.1 8.2 0.0019 18.1 1.2 5.8 3 2 3 6 6 6 3 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 KFQ98892.1 - 0.002 18.2 1.1 0.002 18.2 1.1 6.2 2 2 6 8 8 7 3 Zinc ribbon domain FYDLN_acid PF09538.10 KFQ98892.1 - 0.0022 18.6 11.4 5 7.8 0.1 6.1 1 1 6 7 7 7 1 Protein of unknown function (FYDLN_acid) zf-C2H2_6 PF13912.6 KFQ98892.1 - 0.0033 17.4 0.4 0.0033 17.4 0.4 8.5 9 0 0 9 9 8 3 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFQ98892.1 - 0.0093 15.8 0.2 0.0093 15.8 0.2 6.3 7 1 0 7 7 6 1 zinc-finger of a C2HC-type C1_4 PF07975.12 KFQ98892.1 - 0.011 16.0 18.4 3.8 7.8 0.1 5.5 1 1 5 7 7 7 0 TFIIH C1-like domain XPA_N PF01286.18 KFQ98892.1 - 0.014 15.5 19.6 7 6.8 0.4 7.0 7 0 0 7 7 7 0 XPA protein N-terminal DZR PF12773.7 KFQ98892.1 - 0.016 15.2 31.5 2.4e+02 1.8 21.8 4.9 1 1 1 2 2 2 0 Double zinc ribbon zf-AN1 PF01428.16 KFQ98892.1 - 0.016 15.3 25.5 4.7 7.5 0.2 7.7 8 0 0 8 8 8 0 AN1-like Zinc finger DUF3268 PF11672.8 KFQ98892.1 - 0.036 14.4 13.9 0.66 10.3 0.3 4.2 4 1 1 5 5 4 0 zinc-finger-containing domain zf-RING_7 PF02591.15 KFQ98892.1 - 0.12 12.6 0.0 0.12 12.6 0.0 5.0 8 0 0 8 8 4 0 C4-type zinc ribbon domain HypA PF01155.19 KFQ98892.1 - 0.13 12.3 16.8 3.8 7.6 0.3 4.4 1 1 4 5 5 5 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RRPl_C4 PF17026.5 KFQ98892.1 - 0.29 11.3 2.4 5.4 7.2 1.1 2.5 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-MYST PF17772.1 KFQ98892.1 - 0.43 10.2 5.2 7.6 6.2 0.1 4.8 6 1 2 8 8 7 0 MYST family zinc finger domain ADK_lid PF05191.14 KFQ98892.1 - 0.79 9.8 20.3 0.35 10.9 0.5 5.0 3 2 1 4 4 4 0 Adenylate kinase, active site lid zinc_ribbon_9 PF14369.6 KFQ98892.1 - 0.79 10.0 24.8 9.8 6.5 0.1 6.8 7 0 0 7 7 7 0 zinc-ribbon LIM PF00412.22 KFQ98892.1 - 1.2 9.4 16.4 3.1 8.1 0.5 5.5 2 1 5 7 7 7 0 LIM domain DNA_RNApol_7kD PF03604.13 KFQ98892.1 - 1.2 8.8 31.0 5.4 6.8 0.1 7.1 8 0 0 8 8 8 0 DNA directed RNA polymerase, 7 kDa subunit zf-UBP PF02148.19 KFQ98892.1 - 1.3 9.4 24.4 32 5.0 4.4 5.6 1 1 3 4 4 4 0 Zn-finger in ubiquitin-hydrolases and other protein zf-Di19 PF05605.12 KFQ98892.1 - 2.4 8.5 20.9 3.6 7.9 3.4 4.7 2 2 3 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KFQ98892.1 - 4.5 7.7 16.5 51 4.3 0.4 6.0 1 1 7 8 8 8 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KFQ98892.1 - 8.8 6.2 36.4 0.44 10.3 0.4 7.1 8 0 0 8 8 8 0 zinc-finger C2H2-type YhfH PF14149.6 KFQ98892.1 - 8.9 6.4 21.3 51 4.0 0.2 6.4 7 0 0 7 7 7 0 YhfH-like protein zf-H2C2_2 PF13465.6 KFQ98893.1 - 1.4e-71 233.9 55.1 5.8e-08 32.8 0.1 12.5 13 0 0 13 13 13 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ98893.1 - 1.6e-67 220.4 58.8 6.5e-06 26.3 0.2 12.1 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ98893.1 - 5.6e-36 120.1 59.2 0.004 17.9 0.3 12.0 12 0 0 12 12 12 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ98893.1 - 7.5e-15 54.8 14.8 0.31 11.4 0.0 10.1 10 0 0 10 10 10 3 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFQ98893.1 - 3.9e-11 42.3 26.1 1.5 8.5 0.1 10.9 11 0 0 11 11 11 2 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFQ98893.1 - 7.1e-11 42.0 42.2 0.0078 16.3 1.1 8.0 7 3 1 8 8 8 5 Zinc ribbon domain XPA_N PF01286.18 KFQ98893.1 - 2.2e-09 37.2 30.8 2.8 8.0 0.1 10.8 11 0 0 11 11 11 1 XPA protein N-terminal C1_4 PF07975.12 KFQ98893.1 - 1.8e-08 34.4 21.6 0.04 14.1 0.6 7.4 2 1 4 7 7 7 2 TFIIH C1-like domain zf-C2H2_6 PF13912.6 KFQ98893.1 - 3.9e-08 33.1 68.1 0.091 12.8 0.4 11.9 11 1 0 11 11 11 5 C2H2-type zinc finger zinc_ribbon_15 PF17032.5 KFQ98893.1 - 3.8e-07 30.8 23.0 0.57 11.0 1.2 5.9 1 1 8 9 9 9 6 zinc-ribbon family Zn_ribbon_recom PF13408.6 KFQ98893.1 - 7.4e-07 29.6 56.0 1 9.9 0.3 10.3 4 2 6 10 10 10 3 Recombinase zinc beta ribbon domain DNA_RNApol_7kD PF03604.13 KFQ98893.1 - 1.4e-06 27.9 47.7 4.3 7.1 0.2 11.1 11 0 0 11 11 11 3 DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_11 PF16622.5 KFQ98893.1 - 5.6e-06 26.0 54.9 0.21 11.4 0.6 10.4 11 0 0 11 11 10 4 zinc-finger C2H2-type zf-LYAR PF08790.11 KFQ98893.1 - 0.00028 20.7 21.7 11 6.0 0.1 9.4 11 0 0 11 11 10 0 LYAR-type C2HC zinc finger HypA PF01155.19 KFQ98893.1 - 0.00047 20.1 27.5 1.5 8.8 0.3 5.8 1 1 4 6 6 6 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KFQ98893.1 - 0.0007 19.6 44.9 1.8e+04 -26.5 44.8 6.3 1 1 0 1 1 0 0 Double zinc ribbon DUF3268 PF11672.8 KFQ98893.1 - 0.0017 18.7 25.4 0.07 13.5 0.2 5.8 2 2 5 8 8 8 2 zinc-finger-containing domain Zn_ribbon_SprT PF17283.2 KFQ98893.1 - 0.014 15.3 49.0 0.15 12.0 0.5 8.5 4 3 5 9 9 9 0 SprT-like zinc ribbon domain LIM PF00412.22 KFQ98893.1 - 0.019 15.2 28.9 0.16 12.2 0.6 7.2 2 2 7 9 9 9 0 LIM domain zf-trcl PF13451.6 KFQ98893.1 - 0.024 14.5 40.0 3.2 7.7 0.0 10.1 9 2 0 9 9 9 0 Probable zinc-ribbon domain CpXC PF14353.6 KFQ98893.1 - 0.077 13.0 27.6 3.8 7.6 0.0 9.3 6 4 4 10 10 10 0 CpXC protein Yippee-Mis18 PF03226.14 KFQ98893.1 - 2.8 8.2 23.0 51 4.1 0.8 6.3 2 1 2 4 4 4 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf_C2H2_ZHX PF18387.1 KFQ98893.1 - 2.9 7.6 40.7 4.4 7.0 0.4 9.4 2 2 8 10 10 10 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_3rep PF18868.1 KFQ98893.1 - 4.6 7.9 28.6 83 3.9 0.2 7.6 1 1 4 5 5 5 0 Zinc finger C2H2-type, 3 repeats Pkinase PF00069.25 KFQ98894.1 - 3.6e-59 200.3 0.0 4.2e-59 200.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ98894.1 - 1.1e-27 97.0 0.0 1.4e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFQ98894.1 - 0.0021 17.4 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFQ98894.1 - 0.012 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KFQ98894.1 - 0.08 11.9 0.1 0.1 11.5 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain YukC PF10140.9 KFQ98894.1 - 0.18 10.6 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Syntaxin PF00804.25 KFQ98895.1 - 1.4e-51 175.1 13.1 1.8e-51 174.7 13.1 1.2 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KFQ98895.1 - 3.3e-13 49.4 1.0 3.3e-13 49.4 1.0 1.9 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 KFQ98895.1 - 8.8e-06 26.0 4.1 8.8e-06 26.0 4.1 2.5 1 1 1 2 2 2 1 Syntaxin-like protein Lzipper-MIP1 PF14389.6 KFQ98895.1 - 0.002 18.4 0.5 0.002 18.4 0.5 1.9 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 Lge1 PF11488.8 KFQ98895.1 - 0.09 13.0 0.3 0.09 13.0 0.3 3.1 1 1 2 3 3 3 0 Transcriptional regulatory protein LGE1 DUF1910 PF08928.10 KFQ98895.1 - 0.12 12.4 8.3 0.23 11.4 1.4 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF1910) MCM_N PF14551.6 KFQ98895.1 - 0.5 11.0 4.0 1.5 9.5 0.2 2.4 1 1 0 2 2 2 0 MCM N-terminal domain Med9 PF07544.13 KFQ98895.1 - 0.73 10.0 7.0 1.3 9.2 0.5 2.9 1 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 HAUS6_N PF14661.6 KFQ98895.1 - 3.4 7.2 8.1 4.7 6.7 8.1 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Nup54 PF13874.6 KFQ98895.1 - 5.8 7.0 10.0 29 4.7 10.0 2.1 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Apolipoprotein PF01442.18 KFQ98903.1 - 3e-32 112.0 1.5 4.3e-32 111.5 1.5 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain CorA PF01544.18 KFQ98903.1 - 0.037 13.3 0.9 0.041 13.2 0.9 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein BAG6 PF12057.8 KFQ98903.1 - 0.18 11.5 1.1 5.1 6.8 0.4 2.8 1 1 2 3 3 3 0 BCL2-associated athanogene 6 Bud13 PF09736.9 KFQ98904.1 - 6e-48 162.9 16.1 6e-48 162.9 16.1 2.8 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex Lamprin PF06403.11 KFQ98905.1 - 0.035 14.1 0.1 0.037 14.0 0.1 1.1 1 0 0 1 1 1 0 Lamprin Chorion_1 PF01723.16 KFQ98905.1 - 0.84 9.6 3.9 0.94 9.4 3.9 1.2 1 0 0 1 1 1 0 Chorion protein Peptidase_C5 PF00770.18 KFQ98905.1 - 1.1 8.9 2.8 1.1 8.9 2.8 1.2 1 0 0 1 1 1 0 Adenovirus endoprotease Lem_TRP PF08262.11 KFQ98905.1 - 3.1 8.0 0.0 3.1 8.0 0.0 5.2 6 0 0 6 6 6 0 Leucophaea maderae tachykinin-related peptide Ig_3 PF13927.6 KFQ98906.1 - 7.8e-32 109.7 0.6 3.4e-14 53.2 0.1 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFQ98906.1 - 3.1e-25 88.3 0.3 3.3e-10 40.1 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFQ98906.1 - 1.1e-24 86.3 0.1 8.7e-11 41.8 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 KFQ98906.1 - 7e-24 83.8 0.2 8.4e-10 38.7 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFQ98906.1 - 5.5e-18 65.1 2.2 4.2e-07 30.1 0.1 4.4 3 1 1 4 4 4 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFQ98906.1 - 4.2e-12 46.0 0.0 3.7e-10 39.7 0.0 3.2 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFQ98906.1 - 2e-05 24.6 0.0 0.19 11.8 0.0 2.6 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Adeno_E3_CR1 PF02440.15 KFQ98906.1 - 0.00095 18.9 0.5 0.19 11.5 0.0 2.9 3 0 0 3 3 2 1 Adenovirus E3 region protein CR1 C2-set PF05790.15 KFQ98906.1 - 0.0054 16.9 0.0 33 4.7 0.0 4.2 4 0 0 4 4 4 0 Immunoglobulin C2-set domain Syndecan PF01034.20 KFQ98906.1 - 0.017 15.0 0.0 0.7 9.8 0.1 2.4 2 0 0 2 2 2 0 Syndecan domain C1-set PF07654.15 KFQ98906.1 - 0.035 14.5 0.2 0.65 10.4 0.0 2.9 3 0 0 3 3 3 0 Immunoglobulin C1-set domain Ig_C17orf99 PF17736.1 KFQ98906.1 - 0.082 12.9 0.0 0.64 10.1 0.0 2.5 3 1 0 3 3 3 0 C17orf99 Ig domain DUF3439 PF11921.8 KFQ98906.1 - 0.11 12.4 7.4 0.24 11.4 7.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) V-set_2 PF15910.5 KFQ98906.1 - 0.2 11.8 1.3 3.7 7.7 0.1 2.9 2 1 1 3 3 3 0 ICOS V-set domain RNase_T PF00929.24 KFQ98907.1 - 1.4e-20 74.4 0.0 1.8e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 KFQ98907.1 - 0.018 15.1 0.0 0.023 14.7 0.0 1.1 1 0 0 1 1 1 0 3' exoribonuclease, RNase T-like RRM_1 PF00076.22 KFQ98908.1 - 1.1e-08 34.8 0.0 1.5e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-H2C2_2 PF13465.6 KFQ98909.1 - 9.8e-32 108.0 48.1 7.6e-07 29.3 1.2 9.8 10 0 0 10 10 10 7 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ98909.1 - 4.6e-31 104.8 54.5 0.00013 22.5 1.8 9.6 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2 PF00096.26 KFQ98909.1 - 9.3e-27 92.0 57.5 0.00018 21.8 2.6 9.4 9 0 0 9 9 9 8 Zinc finger, C2H2 type BTB PF00651.31 KFQ98909.1 - 7e-26 90.6 3.0 1.4e-25 89.7 3.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_6 PF13912.6 KFQ98909.1 - 1.4e-17 63.2 54.2 6.4e-06 26.0 1.0 10.0 10 0 0 10 10 10 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ98909.1 - 7.7e-15 54.7 39.4 0.00012 22.3 0.4 9.8 10 1 0 10 10 10 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFQ98909.1 - 4.4e-14 52.3 43.0 0.00013 22.2 0.4 9.5 9 0 0 9 9 9 4 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFQ98909.1 - 0.0015 18.9 42.6 0.15 12.4 0.4 8.4 2 2 7 9 9 9 2 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 KFQ98909.1 - 0.002 17.7 35.3 0.11 12.1 0.1 8.1 9 0 0 9 9 9 2 Ubiquitin-Binding Zinc Finger zf-C2H2_8 PF15909.5 KFQ98909.1 - 0.0049 17.1 24.4 1.8 8.9 0.5 4.9 1 1 4 5 5 5 4 C2H2-type zinc ribbon DZR PF12773.7 KFQ98909.1 - 0.0069 16.4 29.7 3.5e+02 1.3 1.5 5.3 2 1 0 2 2 1 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 KFQ98909.1 - 0.0078 16.9 25.1 0.42 11.4 0.4 5.3 1 1 5 6 6 6 4 zinc-ribbon family Endonuclease_7 PF02945.15 KFQ98909.1 - 0.01 15.7 1.5 0.01 15.7 1.5 4.2 2 2 2 4 4 3 0 Recombination endonuclease VII zf-C2H2_3rep PF18868.1 KFQ98909.1 - 0.02 15.6 16.5 16 6.2 11.5 5.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats MIX PF18529.1 KFQ98909.1 - 0.021 14.5 0.1 0.04 13.6 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial membrane-anchored proteins zf-C2H2_11 PF16622.5 KFQ98909.1 - 0.022 14.5 1.4 0.022 14.5 1.4 8.4 9 0 0 9 9 9 0 zinc-finger C2H2-type zf-MYST PF17772.1 KFQ98909.1 - 0.036 13.7 20.7 0.54 9.9 0.5 6.6 6 3 2 8 8 8 0 MYST family zinc finger domain Zn-C2H2_12 PF18112.1 KFQ98909.1 - 0.1 13.1 0.7 0.1 13.1 0.7 5.6 6 0 0 6 6 6 0 Autophagy receptor zinc finger-C2H2 domain zinc_ribbon_2 PF13240.6 KFQ98909.1 - 0.33 10.7 0.1 0.33 10.7 0.1 5.8 7 0 0 7 7 6 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KFQ98909.1 - 0.38 10.9 0.1 0.38 10.9 0.1 6.9 5 3 4 9 9 9 0 Zinc ribbon domain zf-Di19 PF05605.12 KFQ98909.1 - 1.4 9.3 33.8 0.24 11.7 1.7 5.5 3 1 2 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding DUF3268 PF11672.8 KFQ98909.1 - 1.5 9.2 19.8 3.5 8.0 0.2 4.7 4 1 1 5 5 5 0 zinc-finger-containing domain DUF2197 PF09963.9 KFQ98909.1 - 7.1 7.0 20.0 2.8 8.3 0.2 5.5 5 1 1 6 6 5 0 Uncharacterized protein conserved in bacteria (DUF2197) Spt46 PF17734.1 KFQ98909.1 - 9.2 6.0 11.4 1.5 8.5 0.7 3.1 1 1 2 3 3 3 0 Spermatogenesis-associated protein 46 Neur_chan_LBD PF02931.23 KFQ98910.1 - 8.3e-52 175.8 3.3 1.1e-51 175.4 3.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFQ98910.1 - 1.6e-36 126.6 0.0 2.8e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region UCH PF00443.29 KFQ98911.1 - 2.9e-49 167.9 0.0 3.7e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFQ98911.1 - 0.00027 20.7 1.5 0.031 13.9 1.5 3.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 KFQ98911.1 - 0.045 13.6 0.1 0.17 11.7 0.3 2.0 2 0 0 2 2 2 0 UBA-like domain WD40 PF00400.32 KFQ98935.1 - 7.6e-11 42.4 0.0 3e-05 24.7 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ98935.1 - 5.3e-06 26.6 0.0 1.6e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFQ98935.1 - 0.0016 17.4 0.1 0.0024 16.9 0.1 1.5 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFQ98935.1 - 0.092 12.6 0.0 3.4 7.5 0.0 2.5 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Spc7 PF08317.11 KFQ98936.1 - 0.011 14.7 13.0 0.071 12.0 9.5 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein IFT57 PF10498.9 KFQ98936.1 - 0.019 14.0 7.8 0.051 12.5 7.8 1.7 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 HAUS-augmin3 PF14932.6 KFQ98936.1 - 0.061 12.9 10.4 0.17 11.5 10.4 1.7 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF1664 PF07889.12 KFQ98936.1 - 0.95 9.5 4.7 1.1 9.3 1.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CENP-H PF05837.12 KFQ98936.1 - 1 9.8 9.2 1.1 9.6 6.1 2.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) FapA PF03961.13 KFQ98936.1 - 1.8 7.1 7.7 3.2 6.3 7.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A XhlA PF10779.9 KFQ98936.1 - 5.1 7.4 5.1 1.1 9.5 1.3 1.9 2 0 0 2 2 2 0 Haemolysin XhlA EGF PF00008.27 KFQ98937.1 - 4.2e-32 110.1 89.8 6.1e-10 39.2 10.4 6.9 6 0 0 6 6 6 6 EGF-like domain EGF_2 PF07974.13 KFQ98937.1 - 1.5e-14 54.0 97.1 0.00036 20.8 9.2 6.4 6 0 0 6 6 6 6 EGF-like domain hEGF PF12661.7 KFQ98937.1 - 1.8e-13 50.6 78.4 0.00037 21.0 5.3 7.9 7 0 0 7 7 7 5 Human growth factor-like EGF DUF2448 PF10476.9 KFQ98937.1 - 0.044 13.6 0.0 0.063 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) Laminin_EGF PF00053.24 KFQ98937.1 - 0.045 13.9 68.8 0.077 13.2 7.7 6.5 3 2 3 6 6 6 0 Laminin EGF domain EGF_CA PF07645.15 KFQ98937.1 - 0.08 13.2 77.6 0.083 13.1 8.9 6.7 4 1 1 6 6 6 0 Calcium-binding EGF domain T4_deiodinase PF00837.17 KFQ98938.1 - 4e-36 124.5 0.0 4.6e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase GTP_cyclohydro2 PF00925.20 KFQ98938.1 - 0.23 11.1 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 GTP cyclohydrolase II T4_deiodinase PF00837.17 KFQ98939.1 - 2.9e-54 183.9 0.0 3.3e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase DUF5039 PF16442.5 KFQ98939.1 - 0.091 12.3 0.0 0.092 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5039) B56 PF01603.20 KFQ98940.1 - 1.6e-200 666.4 10.8 2.1e-200 666.0 10.8 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KFQ98940.1 - 0.15 12.0 1.8 2.1 8.3 0.3 2.8 1 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal HSP90 PF00183.18 KFQ98942.1 - 1e-234 780.3 33.5 1.3e-234 779.9 33.5 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KFQ98942.1 - 4.3e-14 53.0 0.1 9.9e-14 51.8 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFQ98942.1 - 6.3e-12 45.5 0.1 2e-11 43.8 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 KFQ98942.1 - 0.1 12.6 1.3 0.35 10.9 0.2 2.3 2 0 0 2 2 2 0 Tumour suppressor protein DUF1198 PF06711.11 KFQ98942.1 - 0.21 11.7 0.6 0.85 9.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1198) Zip PF02535.22 KFQ98942.1 - 0.25 10.5 0.6 0.54 9.4 0.6 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 KFQ98942.1 - 2.9 6.1 14.1 5.7 5.1 14.1 1.4 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.32 KFQ98943.1 - 4.2e-12 46.4 3.7 0.0002 22.1 0.2 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ98943.1 - 2e-08 34.4 0.0 0.49 10.7 0.0 4.2 1 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KFQ98943.1 - 0.00043 20.1 0.0 0.84 9.6 0.0 2.5 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KFQ98943.1 - 0.019 13.9 0.0 0.064 12.2 0.0 1.8 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFQ98943.1 - 0.036 13.9 0.0 0.21 11.5 0.0 2.0 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Pkinase PF00069.25 KFQ98944.1 - 1.1e-67 228.2 0.0 1.4e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ98944.1 - 3.2e-30 105.3 0.0 4.8e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ98944.1 - 0.00018 21.0 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFQ98944.1 - 0.011 15.1 0.1 0.023 14.1 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KFQ98944.1 - 0.016 14.8 0.1 0.05 13.2 0.0 1.7 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF4764 PF15961.5 KFQ98945.1 - 1.7e-128 430.6 16.9 4.4e-83 280.4 8.5 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4764) zf-C2H2 PF00096.26 KFQ98945.1 - 0.016 15.6 0.2 0.036 14.5 0.2 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF4764 PF15961.5 KFQ98946.1 - 1.7e-23 83.3 2.8 1.9e-23 83.2 2.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4764) ACDC PF14733.6 KFQ98946.1 - 0.14 12.5 0.1 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 AP2-coincident C-terminal CK2S PF15011.6 KFQ98947.1 - 0.11 12.4 2.7 0.26 11.1 2.7 1.8 1 1 0 1 1 1 0 Casein Kinase 2 substrate Hyd_WA PF06462.12 KFQ98948.1 - 6.5e-38 128.4 18.6 1e-06 28.6 0.9 8.5 8 0 0 8 8 8 6 Propeller ANAPC4_WD40 PF12894.7 KFQ98948.1 - 0.0012 19.2 0.0 0.0043 17.3 0.0 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFQ98948.1 - 0.0028 18.5 0.0 0.066 14.1 0.0 3.5 2 0 0 2 2 2 1 WD domain, G-beta repeat WD40_like PF17005.5 KFQ98948.1 - 0.015 14.6 0.0 0.12 11.7 0.0 2.2 2 1 1 3 3 3 0 WD40-like domain Ank_5 PF13857.6 KFQ98949.1 - 1.9e-07 31.2 0.2 9.1e-07 29.0 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFQ98949.1 - 5.9e-05 23.5 0.4 0.00092 19.7 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KFQ98949.1 - 0.00012 22.4 2.0 0.00038 20.8 0.1 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KFQ98949.1 - 0.00013 22.5 0.0 0.0005 20.6 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFQ98949.1 - 0.0049 17.3 2.8 0.049 14.2 0.1 3.4 3 0 0 3 3 3 1 Ankyrin repeat Myb_DNA-binding PF00249.31 KFQ98950.1 - 5.6e-17 61.7 0.8 2.3e-09 37.3 0.0 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFQ98950.1 - 1e-05 25.3 12.9 0.00094 19.0 0.1 3.3 3 1 0 3 3 3 2 Myb DNA-binding like ELM2 PF01448.24 KFQ98950.1 - 7.6e-05 23.4 0.0 7.6e-05 23.4 0.0 2.9 2 1 0 2 2 2 1 ELM2 domain Myb_DNA-bind_6 PF13921.6 KFQ98950.1 - 0.00016 21.8 4.1 0.12 12.6 0.1 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Arnt_C PF18583.1 KFQ98950.1 - 0.0083 15.7 0.5 4 7.1 0.1 2.7 2 0 0 2 2 2 2 Aminoarabinose transferase C-terminal domain Homeobox_KN PF05920.11 KFQ98950.1 - 0.064 13.2 0.1 0.2 11.6 0.1 1.9 1 0 0 1 1 1 0 Homeobox KN domain RR_TM4-6 PF06459.12 KFQ98950.1 - 2 8.2 12.6 0.14 12.0 6.4 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 zf-TRAF PF02176.18 KFQ98951.1 - 9.1e-25 87.1 25.6 1.1e-15 58.0 9.0 4.4 1 1 3 4 4 3 2 TRAF-type zinc finger MPS2 PF17060.5 KFQ98951.1 - 0.00073 18.9 6.3 0.0011 18.3 6.3 1.2 1 0 0 1 1 1 1 Monopolar spindle protein 2 Cast PF10174.9 KFQ98951.1 - 0.0027 16.0 11.6 0.0035 15.6 10.7 1.6 1 1 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone ATG16 PF08614.11 KFQ98951.1 - 0.0028 17.9 6.3 0.0028 17.9 6.3 2.2 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Sina PF03145.16 KFQ98951.1 - 0.0037 17.2 7.7 0.0037 17.2 7.7 3.6 2 1 2 4 4 3 2 Seven in absentia protein family zf-C3HC4 PF00097.25 KFQ98951.1 - 0.0064 16.3 15.8 0.0064 16.3 15.8 3.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) FliJ PF02050.16 KFQ98951.1 - 0.0095 16.2 9.3 0.01 16.0 8.3 1.6 1 1 0 1 1 1 1 Flagellar FliJ protein zf-C3HC4_2 PF13923.6 KFQ98951.1 - 0.021 14.7 14.6 0.021 14.7 14.6 3.4 2 1 2 4 4 3 0 Zinc finger, C3HC4 type (RING finger) Spc7 PF08317.11 KFQ98951.1 - 0.028 13.3 14.7 0.042 12.7 14.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Spc29 PF17082.5 KFQ98951.1 - 0.085 12.7 6.3 0.039 13.8 3.5 1.7 1 1 0 1 1 1 0 Spindle Pole Component 29 Tropomyosin_1 PF12718.7 KFQ98951.1 - 0.091 12.9 15.5 0.41 10.8 15.5 2.3 1 1 0 1 1 1 0 Tropomyosin like SPATA24 PF15175.6 KFQ98951.1 - 0.092 12.6 13.4 0.091 12.6 8.0 2.3 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 KxDL PF10241.9 KFQ98951.1 - 0.12 12.7 5.7 0.1 12.9 3.8 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein T3SSipB PF16535.5 KFQ98951.1 - 0.13 12.8 3.8 0.11 13.0 2.2 1.6 1 1 0 1 1 1 0 Type III cell invasion protein SipB DUF1664 PF07889.12 KFQ98951.1 - 0.13 12.3 5.4 0.24 11.4 4.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-RING_6 PF14835.6 KFQ98951.1 - 0.13 12.1 5.7 0.22 11.4 4.2 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein BLOC1_2 PF10046.9 KFQ98951.1 - 0.14 12.4 8.3 0.21 11.9 3.9 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.8 KFQ98951.1 - 0.17 12.0 15.8 0.077 13.1 10.8 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Exonuc_VII_L PF02601.15 KFQ98951.1 - 0.95 9.0 9.0 1.4 8.4 9.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 KFQ98951.1 - 1.4 8.1 6.8 2.4 7.3 6.8 1.5 1 0 0 1 1 1 0 TMPIT-like protein LMBR1 PF04791.16 KFQ98951.1 - 1.6 7.5 4.3 2.2 7.1 4.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Amnionless PF14828.6 KFQ98952.1 - 2.7e-134 448.4 0.0 3.1e-134 448.2 0.0 1.0 1 0 0 1 1 1 1 Amnionless SecG PF03840.14 KFQ98952.1 - 0.15 12.2 2.8 0.13 12.3 1.2 1.7 2 0 0 2 2 2 0 Preprotein translocase SecG subunit FixQ PF05545.11 KFQ98952.1 - 0.21 11.6 0.4 0.44 10.5 0.4 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ CNH PF00780.22 KFQ98953.1 - 1.1e-71 241.7 0.1 2.2e-71 240.7 0.1 1.5 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.25 KFQ98953.1 - 8.4e-56 189.3 0.0 8.4e-56 189.3 0.0 2.7 3 0 0 3 3 3 1 Protein kinase domain KELK PF15796.5 KFQ98953.1 - 6e-32 110.0 20.1 6e-32 110.0 20.1 7.2 6 2 2 8 8 5 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pkinase_Tyr PF07714.17 KFQ98953.1 - 4.3e-29 101.6 0.0 4.3e-29 101.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase DMPK_coil PF08826.10 KFQ98953.1 - 3.2e-26 91.2 11.3 3.2e-26 91.2 11.3 9.3 7 2 3 10 10 9 1 DMPK coiled coil domain like C1_1 PF00130.22 KFQ98953.1 - 4.6e-10 39.2 5.9 1.1e-09 38.1 5.9 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 KFQ98953.1 - 4.2e-07 29.6 0.0 1.6e-06 27.7 0.0 2.0 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 KFQ98953.1 - 0.00049 20.7 1.1 0.0011 19.6 1.1 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain PBD PF00786.28 KFQ98953.1 - 0.00093 19.5 0.2 0.0039 17.5 0.2 2.2 1 0 0 1 1 1 1 P21-Rho-binding domain Myosin_tail_1 PF01576.19 KFQ98953.1 - 0.002 16.0 103.5 0.0044 14.9 75.9 3.3 1 1 2 3 3 3 2 Myosin tail PH PF00169.29 KFQ98953.1 - 0.014 15.9 0.0 0.11 13.0 0.0 2.6 2 0 0 2 2 2 0 PH domain C1_2 PF03107.16 KFQ98953.1 - 0.017 15.4 4.9 0.043 14.1 4.9 1.7 1 0 0 1 1 1 0 C1 domain Filament PF00038.21 KFQ98953.1 - 0.29 10.7 86.8 0.021 14.4 2.4 5.2 1 1 2 5 5 5 0 Intermediate filament protein Baculo_PEP_C PF04513.12 KFQ98953.1 - 2.1 8.4 18.4 0.67 10.0 0.8 4.3 2 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3450 PF11932.8 KFQ98953.1 - 8.1 5.7 71.4 0.072 12.4 7.4 5.5 2 1 3 6 6 6 0 Protein of unknown function (DUF3450) Lbh PF15317.6 KFQ98954.1 - 3e-19 69.8 0.3 3.4e-19 69.5 0.3 1.1 1 0 0 1 1 1 1 Cardiac transcription factor regulator, Developmental protein Sec6 PF06046.13 KFQ98956.1 - 7.5e-73 245.8 4.2 9.5e-73 245.5 4.2 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 Clusterin PF01093.17 KFQ98956.1 - 0.077 12.0 1.0 0.14 11.1 0.3 1.7 2 0 0 2 2 2 0 Clusterin Sec6 PF06046.13 KFQ98957.1 - 6.1e-78 262.6 8.7 7e-78 262.4 8.7 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec6 HD_2 PF12917.7 KFQ98957.1 - 0.094 12.5 3.2 8.3 6.1 0.0 3.0 3 0 0 3 3 3 0 HD containing hydrolase-like enzyme SHS2_Rpb7-N PF03876.17 KFQ98958.1 - 0.18 12.2 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 eIF-5_eIF-2B PF01873.17 KFQ98959.1 - 1.5e-42 144.2 0.6 1.2e-41 141.2 0.1 2.5 3 0 0 3 3 3 1 Domain found in IF2B/IF5 W2 PF02020.18 KFQ98959.1 - 8.6e-22 77.1 1.6 8.6e-22 77.1 1.6 2.8 2 1 1 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon DUF3655 PF12379.8 KFQ98959.1 - 0.7 10.2 8.4 0.91 9.9 1.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3655) Elf1 PF05129.13 KFQ98959.1 - 1.2 9.3 4.0 9.4 6.4 0.7 2.9 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Pkinase PF00069.25 KFQ98960.1 - 1.5e-75 254.0 0.0 2.4e-75 253.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ98960.1 - 2.4e-45 154.8 0.0 4.8e-45 153.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KFQ98960.1 - 5e-22 77.4 0.3 1.7e-20 72.6 0.0 2.3 2 0 0 2 2 2 1 Kinase associated domain 1 Kinase-like PF14531.6 KFQ98960.1 - 1e-07 31.6 0.0 1.8e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like UBA PF00627.31 KFQ98960.1 - 1.2e-05 25.1 0.0 2.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RIO1 PF01163.22 KFQ98960.1 - 0.00029 20.5 0.2 0.00059 19.5 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KFQ98960.1 - 0.0011 18.4 0.2 0.002 17.5 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UBA_2 PF08587.11 KFQ98960.1 - 0.0063 16.6 0.3 0.015 15.4 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Haspin_kinase PF12330.8 KFQ98960.1 - 0.05 12.5 0.1 0.05 12.5 0.1 1.6 2 0 0 2 2 2 0 Haspin like kinase domain ATP-gua_Ptrans PF00217.19 KFQ98961.1 - 1.8e-83 279.2 0.0 2.4e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 KFQ98961.1 - 1.4e-34 118.3 0.1 2e-16 60.1 0.0 2.4 2 0 0 2 2 2 2 ATP:guanido phosphotransferase, N-terminal domain GCD14 PF08704.10 KFQ98962.1 - 2.1e-109 364.9 0.0 2.5e-109 364.7 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 KFQ98962.1 - 2.3e-07 30.7 0.0 3.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFQ98962.1 - 2.7e-05 24.0 0.0 3.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KFQ98962.1 - 0.0015 19.2 0.0 0.0029 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KFQ98962.1 - 0.0057 17.7 0.0 0.0099 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 KFQ98962.1 - 0.023 14.4 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_12 PF08242.12 KFQ98962.1 - 0.041 14.6 0.0 0.087 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GCD14_N PF14801.6 KFQ98962.1 - 0.049 13.5 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term CMAS PF02353.20 KFQ98962.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase BAG PF02179.16 KFQ98963.1 - 3.8e-50 168.2 21.7 1.5e-14 54.1 0.4 5.2 5 0 0 5 5 5 5 BAG domain DUF382 PF04037.13 KFQ98963.1 - 0.02 15.0 1.7 0.15 12.3 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF382) Snapin_Pallidin PF14712.6 KFQ98963.1 - 0.054 13.9 7.7 2.8 8.4 4.7 3.2 2 0 0 2 2 2 0 Snapin/Pallidin SOUL PF04832.12 KFQ98963.1 - 0.068 13.3 4.3 5.7 7.1 0.2 3.3 2 2 1 3 3 3 0 SOUL heme-binding protein DUF2682 PF10909.8 KFQ98963.1 - 0.12 12.9 4.5 2.6 8.6 0.2 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2682) DAGK_cat PF00781.24 KFQ98963.1 - 0.66 9.6 2.4 8.3 6.1 0.1 3.1 3 0 0 3 3 3 0 Diacylglycerol kinase catalytic domain DUF4061 PF13270.6 KFQ98963.1 - 1.6 9.1 5.6 6.4 7.2 1.2 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) PDGF_N PF04692.13 KFQ98963.1 - 3.5 8.5 7.1 0.44 11.4 0.3 3.0 4 0 0 4 4 4 0 Platelet-derived growth factor, N terminal region DUF2315 PF10231.9 KFQ98964.1 - 5.5e-48 162.1 1.6 6.9e-48 161.8 1.6 1.1 1 0 0 1 1 1 1 Apoptogenic protein 1 Sugarporin_N PF11471.8 KFQ98964.1 - 0.079 12.9 0.3 0.14 12.1 0.3 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension V-ATPase_G PF03179.15 KFQ98964.1 - 0.37 11.4 3.6 0.56 10.8 3.6 1.4 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit TPR_12 PF13424.6 KFQ98965.1 - 1e-68 227.6 23.2 1.4e-20 73.3 2.6 5.8 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 KFQ98965.1 - 6.6e-62 203.9 17.0 1.2e-15 56.8 0.0 7.1 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 KFQ98965.1 - 8.4e-33 110.0 16.9 4.2e-06 26.4 0.0 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ98965.1 - 7.5e-29 98.3 31.3 1.4e-07 31.0 0.5 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ98965.1 - 8.1e-21 72.4 27.2 0.00036 20.4 2.7 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ98965.1 - 8.1e-14 50.6 26.9 0.0015 18.6 0.1 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFQ98965.1 - 8.3e-14 52.0 9.0 0.0003 21.4 1.9 6.0 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KFQ98965.1 - 9.5e-14 51.5 9.4 6e-13 48.9 2.6 3.4 3 1 0 3 3 3 1 MalT-like TPR region TPR_19 PF14559.6 KFQ98965.1 - 3.7e-13 49.8 8.8 3e-05 24.4 0.1 4.8 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFQ98965.1 - 1.2e-10 41.3 10.1 0.9 10.5 0.3 6.9 3 1 3 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFQ98965.1 - 4.5e-10 39.2 10.1 0.027 14.8 0.2 6.8 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 KFQ98965.1 - 2e-07 30.9 0.0 10 7.1 0.1 6.8 8 0 0 8 8 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFQ98965.1 - 4.6e-07 30.0 12.0 0.017 15.4 0.5 4.3 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 KFQ98965.1 - 0.00017 21.6 2.2 0.13 12.5 0.0 4.5 6 0 0 6 6 4 1 PPR repeat JIP_LZII PF16471.5 KFQ98965.1 - 0.0078 16.4 7.7 0.0078 16.4 7.7 2.8 1 1 0 2 2 2 1 JNK-interacting protein leucine zipper II TMF_TATA_bd PF12325.8 KFQ98965.1 - 0.02 15.1 10.9 0.02 15.1 10.9 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding WbqC PF08889.11 KFQ98965.1 - 0.039 13.9 7.7 10 5.9 0.0 4.1 3 1 1 4 4 4 0 WbqC-like protein family GHL5 PF14872.6 KFQ98965.1 - 0.12 10.4 5.9 0.18 9.8 5.9 1.2 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 SHNi-TPR PF10516.9 KFQ98965.1 - 0.12 11.9 4.7 9.6 5.8 0.1 4.6 5 0 0 5 5 5 0 SHNi-TPR PPR_2 PF13041.6 KFQ98965.1 - 0.14 12.3 3.1 3.3 8.0 0.0 3.6 4 0 0 4 4 3 0 PPR repeat family DUF4919 PF16266.5 KFQ98965.1 - 0.21 11.5 0.1 0.21 11.5 0.1 3.4 3 2 1 4 4 4 0 Domain of unknown function (DUF4919) DUF627 PF04781.12 KFQ98965.1 - 0.21 11.6 5.5 2.3 8.3 0.1 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF627) COG2 PF06148.11 KFQ98965.1 - 0.47 10.6 9.1 0.25 11.4 5.9 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_11 PF13414.6 KFQ98965.1 - 0.97 9.2 20.2 0.28 10.9 0.7 6.2 6 0 0 6 6 6 0 TPR repeat MIT PF04212.18 KFQ98965.1 - 4.1 7.5 17.1 29 4.8 3.2 6.0 4 2 2 6 6 6 0 MIT (microtubule interacting and transport) domain HIP1_clath_bdg PF16515.5 KFQ98965.1 - 9 7.0 22.5 28 5.4 9.5 3.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 YabA PF06156.13 KFQ98965.1 - 9.4 6.9 19.4 0.11 13.1 5.3 3.8 3 0 0 3 3 3 0 Initiation control protein YabA Rad51 PF08423.11 KFQ98966.1 - 4.1e-38 131.1 0.0 5.3e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KFQ98966.1 - 4.7e-05 23.0 0.5 0.015 14.8 0.0 2.3 1 1 0 2 2 2 2 recA bacterial DNA recombination protein ATPase PF06745.13 KFQ98966.1 - 7.5e-05 22.2 0.0 0.00015 21.2 0.0 1.5 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 KFQ98966.1 - 9.3e-05 22.1 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_pol_A_CTD PF03118.15 KFQ98966.1 - 0.016 14.9 0.1 0.034 13.9 0.1 1.5 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain ZFYVE21_C PF16696.5 KFQ98967.1 - 6.2e-54 181.1 0.1 7.7e-54 180.8 0.1 1.1 1 0 0 1 1 1 1 Zinc finger FYVE domain-containing protein 21 C-terminus FYVE PF01363.21 KFQ98967.1 - 6.6e-12 45.4 23.5 1.3e-11 44.5 23.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger Ank_4 PF13637.6 KFQ98968.1 - 7.7e-17 61.4 1.4 7.6e-12 45.5 0.6 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFQ98968.1 - 8.9e-17 61.5 0.0 1.8e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) SH3_1 PF00018.28 KFQ98968.1 - 1.1e-13 50.6 1.4 2.2e-13 49.6 1.4 1.6 1 0 0 1 1 1 1 SH3 domain Ank PF00023.30 KFQ98968.1 - 2.6e-13 49.7 1.4 2.1e-05 24.7 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFQ98968.1 - 1.1e-12 46.9 0.7 2.4e-05 24.4 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat SH3_9 PF14604.6 KFQ98968.1 - 6e-11 42.0 0.2 1.5e-10 40.8 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFQ98968.1 - 4.3e-10 39.1 0.0 9.5e-10 38.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ank_5 PF13857.6 KFQ98968.1 - 4.4e-08 33.2 0.2 1.4e-06 28.4 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Mit_proteolip PF08039.11 KFQ98970.1 - 1.1e-10 41.8 2.4 1.1e-10 41.8 2.4 1.0 1 0 0 1 1 1 1 Mitochondrial proteolipid RD3 PF14473.6 KFQ98971.1 - 3.9e-52 175.6 3.0 5.5e-52 175.1 3.0 1.2 1 0 0 1 1 1 1 RD3 protein THAP PF05485.12 KFQ98971.1 - 0.084 13.8 1.2 0.39 11.7 0.1 2.2 2 1 0 2 2 2 0 THAP domain Med22 PF06179.12 KFQ98971.1 - 0.13 12.5 0.3 0.13 12.5 0.3 1.8 2 0 0 2 2 2 0 Surfeit locus protein 5 subunit 22 of Mediator complex HA2 PF04408.23 KFQ98972.1 - 8.6e-15 54.9 0.0 2.3e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) TUDOR PF00567.24 KFQ98972.1 - 1.4e-14 54.2 0.0 3.8e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Tudor domain Helicase_C PF00271.31 KFQ98972.1 - 4.8e-14 52.6 0.0 1.5e-13 51.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Asparaginase PF00710.20 KFQ98973.1 - 6.2e-60 202.0 0.0 6.3e-59 198.7 0.0 2.1 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KFQ98973.1 - 1.1e-29 103.0 0.0 2.2e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 KFQ98973.1 - 1.6e-16 60.6 0.0 6.1e-14 52.4 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ98973.1 - 2.6e-16 59.8 0.1 3e-10 40.4 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFQ98973.1 - 5.2e-11 42.6 0.1 2e-05 24.8 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KFQ98973.1 - 1.2e-10 41.3 0.1 2.2e-06 27.9 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFQ98973.1 - 2.7e-10 39.6 0.2 5e-05 23.4 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Kinesin PF00225.23 KFQ98974.1 - 3.4e-60 203.7 0.0 6.2e-60 202.9 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFQ98974.1 - 1.5e-16 60.7 0.0 4.6e-16 59.1 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding DUF1640 PF07798.11 KFQ98974.1 - 0.74 9.8 5.9 1.6 8.7 5.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) FH2 PF02181.23 KFQ98976.1 - 1.5e-78 264.5 14.9 2.5e-78 263.8 14.9 1.3 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 KFQ98976.1 - 2.1e-31 109.1 4.9 2.1e-31 109.1 4.9 2.4 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 KFQ98976.1 - 2e-17 63.4 0.3 2e-17 63.4 0.3 2.1 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH1 PF06346.12 KFQ98976.1 - 7.1e-08 32.3 64.3 7.1e-08 32.3 64.3 2.3 1 1 1 2 2 2 1 Formin Homology Region 1 WH2 PF02205.20 KFQ98976.1 - 0.00018 21.2 0.1 0.00054 19.7 0.1 1.9 1 0 0 1 1 1 1 WH2 motif CDT1 PF08839.11 KFQ98976.1 - 0.0053 17.1 2.2 0.018 15.4 2.2 1.9 1 1 0 1 1 1 1 DNA replication factor CDT1 like DUF3361 PF11841.8 KFQ98976.1 - 0.085 12.8 0.2 0.52 10.3 0.1 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3361) Adenylsucc_synt PF00709.21 KFQ98977.1 - 3.6e-162 540.1 0.0 4e-162 539.9 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase hSac2 PF12456.8 KFQ98977.1 - 0.081 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Inositol phosphatase DUF5442 PF17514.2 KFQ98977.1 - 0.092 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5442) MBF1 PF08523.10 KFQ98977.1 - 0.15 12.5 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 Multiprotein bridging factor 1 Siva PF05458.12 KFQ98978.1 - 4.4e-22 78.6 24.1 4.6e-22 78.5 24.1 1.0 1 0 0 1 1 1 1 Cd27 binding protein (Siva) Pkinase PF00069.25 KFQ98979.1 - 1.5e-78 263.9 0.0 2e-78 263.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ98979.1 - 8.7e-36 123.5 0.0 1.3e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KFQ98979.1 - 1.1e-11 45.2 0.1 2.6e-11 43.9 0.1 1.7 1 0 0 1 1 1 1 PH domain Pkinase_C PF00433.24 KFQ98979.1 - 1.3e-10 41.8 3.3 3.4e-10 40.5 3.3 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFQ98979.1 - 9.4e-09 35.0 0.0 8e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 KFQ98979.1 - 0.043 12.9 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PH_11 PF15413.6 KFQ98979.1 - 0.069 13.6 0.3 0.39 11.2 0.0 2.3 3 0 0 3 3 3 0 Pleckstrin homology domain APH PF01636.23 KFQ98979.1 - 0.16 11.9 0.0 0.45 10.4 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family BTB PF00651.31 KFQ98980.1 - 2.6e-26 92.0 0.6 4.3e-26 91.3 0.6 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.6 KFQ98980.1 - 1.6e-13 50.3 31.0 0.00022 21.8 2.9 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KFQ98980.1 - 4.6e-13 48.8 31.4 0.00054 20.3 1.5 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ98980.1 - 2.8e-12 46.5 26.5 2.6e-07 30.8 1.3 5.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFQ98980.1 - 7.4e-05 22.9 0.6 0.016 15.5 0.0 4.5 6 0 0 6 6 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFQ98980.1 - 0.0005 20.4 13.4 0.11 12.9 0.1 4.9 5 0 0 5 5 5 2 Zinc-finger of C2H2 type Zn-C2H2_12 PF18112.1 KFQ98980.1 - 0.0056 17.1 1.7 0.0056 17.1 1.7 3.3 3 0 0 3 3 3 1 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_6 PF13912.6 KFQ98980.1 - 0.037 14.0 22.1 0.72 9.9 0.2 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFQ98980.1 - 0.063 13.0 0.6 0.063 13.0 0.6 4.2 4 0 0 4 4 4 0 zinc-finger C2H2-type GAGA PF09237.11 KFQ98980.1 - 0.32 10.8 8.2 0.53 10.1 0.2 3.3 2 1 1 3 3 3 0 GAGA factor zf-LYAR PF08790.11 KFQ98980.1 - 0.91 9.5 9.5 5 7.1 0.2 3.8 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf_ZIC PF18366.1 KFQ98980.1 - 2.8 8.1 14.5 7.4 6.8 0.6 4.8 3 1 2 5 5 5 0 Zic proteins zinc finger domain FYVE PF01363.21 KFQ98980.1 - 5.7 7.1 17.7 1.6 8.9 2.8 3.9 2 1 2 4 4 4 0 FYVE zinc finger CEP170_C PF15308.6 KFQ98981.1 - 0 1028.6 56.4 0 1028.6 56.4 3.0 3 0 0 3 3 3 1 CEP170 C-terminus FHA PF00498.26 KFQ98981.1 - 5.7e-18 65.0 0.2 1.5e-17 63.7 0.2 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFQ98981.1 - 1.7e-09 37.9 0.0 3.8e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Transposase_22 PF02994.14 KFQ98981.1 - 0.023 14.8 0.8 0.068 13.4 0.8 1.8 1 0 0 1 1 1 0 L1 transposable element RBD-like domain Syntaxin_2 PF14523.6 KFQ98981.1 - 1.3 9.5 11.3 2.8 8.4 2.5 4.5 4 0 0 4 4 4 0 Syntaxin-like protein PLDc_3 PF13918.6 KFQ98982.1 - 5e-37 127.3 0.0 8e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 PLD-like domain PLDc_2 PF13091.6 KFQ98982.1 - 3.8e-24 85.1 1.0 8.4e-12 45.1 0.1 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KFQ98982.1 - 1.6e-13 50.2 4.3 7.3e-09 35.5 0.8 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Myosin_head PF00063.21 KFQ98992.1 - 1.1e-197 658.4 2.1 1.1e-197 658.4 2.1 2.8 4 0 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KFQ98992.1 - 3.1e-72 243.9 131.4 3.8e-72 243.6 131.4 1.1 1 0 0 1 1 1 1 Myosin tail DUF1664 PF07889.12 KFQ98992.1 - 3.2e-06 27.2 73.4 0.0019 18.3 9.1 7.5 2 1 4 7 7 7 4 Protein of unknown function (DUF1664) IQ PF00612.27 KFQ98992.1 - 0.0077 15.9 2.6 0.044 13.6 0.5 2.6 2 0 0 2 2 2 1 IQ calmodulin-binding motif Filament PF00038.21 KFQ98992.1 - 0.037 13.6 108.6 0.09 12.3 11.1 5.4 1 1 4 5 5 5 0 Intermediate filament protein DASH_Dad1 PF08649.10 KFQ98992.1 - 0.44 10.8 3.7 1.9 8.7 0.3 3.7 2 1 0 2 2 2 0 DASH complex subunit Dad1 ERM PF00769.19 KFQ98992.1 - 0.56 10.0 134.5 0.43 10.4 14.0 5.8 1 1 4 5 5 5 0 Ezrin/radixin/moesin family KASH_CCD PF14662.6 KFQ98992.1 - 1.7 8.4 115.8 0.064 13.1 13.5 5.8 1 1 4 5 5 5 0 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 KFQ98992.1 - 5.5 6.3 122.9 1.1 8.6 28.8 6.3 1 1 4 5 5 5 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.8 KFQ98992.1 - 8 3.8 109.7 2.7 5.4 47.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TetR_C_8 PF14278.6 KFQ98996.1 - 0.1 12.7 0.0 0.1 12.7 0.0 1.0 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region SCO1-SenC PF02630.14 KFQ98997.1 - 9.2e-42 142.1 0.0 1.1e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KFQ98997.1 - 2.3e-05 24.3 0.0 4e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KFQ98997.1 - 0.0013 19.0 0.0 0.0019 18.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Metallophos PF00149.28 KFQ98998.1 - 5.2e-07 30.4 0.1 7.3e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TMEM220 PF15071.6 KFQ98999.1 - 1.2e-14 54.9 1.5 1.3e-14 54.8 0.3 1.6 2 0 0 2 2 2 1 Transmembrane family 220, helix Pkinase PF00069.25 KFQ99000.1 - 1.4e-60 204.9 0.0 1.7e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ99000.1 - 7.7e-39 133.5 0.0 9.8e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ99000.1 - 5.7e-07 29.1 0.0 8.4e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KFQ99000.1 - 0.00015 21.0 0.1 0.00022 20.4 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 KFQ99000.1 - 0.00054 19.0 0.0 0.00082 18.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KFQ99000.1 - 0.0029 16.5 0.0 0.014 14.2 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase DXP_redisom_C PF08436.12 KFQ99000.1 - 0.055 13.6 0.0 4.7 7.4 0.0 2.4 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain APH PF01636.23 KFQ99000.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFQ99000.1 - 0.16 11.5 0.1 0.26 10.8 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase BRICHOS PF04089.14 KFQ99003.1 - 1.2e-21 76.7 0.0 1.6e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 BRICHOS domain ssDBP PF17878.1 KFQ99003.1 - 0.11 12.7 0.0 2.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Single-stranded DNA-binding protein Cadherin PF00028.17 KFQ99004.1 - 1.7e-86 284.8 0.0 1.6e-18 66.9 0.0 6.3 6 0 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.12 KFQ99004.1 - 2.5e-15 56.1 0.0 5.2e-11 42.2 0.0 4.6 6 0 0 6 6 6 2 Cadherin-like TMEM154 PF15102.6 KFQ99004.1 - 0.05 13.5 0.1 0.099 12.5 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family OLF PF02191.16 KFQ99005.1 - 7.1e-83 278.0 9.0 7.1e-83 278.0 9.0 1.5 2 0 0 2 2 2 1 Olfactomedin-like domain DTW PF03942.15 KFQ99009.1 - 4.6e-41 140.7 0.4 5.5e-41 140.5 0.4 1.1 1 0 0 1 1 1 1 DTW domain DUF758 PF05527.11 KFQ99010.1 - 1.2e-77 260.0 8.5 1.4e-77 259.8 8.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) Pico_P2B PF01552.17 KFQ99010.1 - 0.0029 17.7 1.1 0.0054 16.9 0.4 1.9 2 1 0 2 2 2 1 Picornavirus 2B protein DUF2408 PF10303.9 KFQ99010.1 - 0.031 14.8 3.8 0.058 14.0 2.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) HD_3 PF13023.6 KFQ99010.1 - 0.034 14.1 0.8 0.075 13.0 1.0 1.5 2 0 0 2 2 2 0 HD domain DUF459 PF04311.13 KFQ99010.1 - 0.038 13.0 0.3 0.051 12.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF459) DUF4771 PF15995.5 KFQ99010.1 - 0.038 14.3 1.0 0.048 13.9 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4771) Nup54 PF13874.6 KFQ99010.1 - 0.049 13.8 3.2 0.043 13.9 1.7 1.7 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 MaoC_dehydratas PF01575.19 KFQ99011.1 - 7.9e-39 132.0 0.0 1.5e-38 131.1 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain adh_short_C2 PF13561.6 KFQ99011.1 - 2.6e-27 95.9 0.1 6.2e-27 94.7 0.1 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFQ99011.1 - 1.8e-26 92.8 0.1 4.1e-26 91.6 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase SCP2 PF02036.17 KFQ99011.1 - 1.5e-24 86.4 0.3 3.2e-24 85.4 0.3 1.6 1 0 0 1 1 1 1 SCP-2 sterol transfer family KR PF08659.10 KFQ99011.1 - 8e-10 38.9 0.0 1.4e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 KR domain MaoC_dehydrat_N PF13452.6 KFQ99011.1 - 1.4e-08 34.9 0.0 6.1e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Alkyl_sulf_C PF14864.6 KFQ99011.1 - 4.8e-06 26.9 0.1 1e-05 25.8 0.1 1.5 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal ApoC-I PF04691.12 KFQ99011.1 - 0.14 12.1 0.2 0.57 10.2 0.0 2.0 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) Homeodomain PF00046.29 KFQ99015.1 - 3.5e-22 78.0 5.3 5.3e-22 77.4 5.3 1.3 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 KFQ99015.1 - 0.00052 19.4 0.4 0.0011 18.4 0.4 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 KFQ99015.1 - 0.0011 18.8 0.6 0.0047 16.8 0.1 2.1 2 0 0 2 2 2 1 Homeobox KN domain Pro-kuma_activ PF09286.11 KFQ99015.1 - 0.0058 16.9 0.2 0.0086 16.4 0.2 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Antimicrobial21 PF14861.6 KFQ99015.1 - 0.014 15.1 1.4 0.026 14.2 1.4 1.4 1 0 0 1 1 1 0 Plant antimicrobial peptide YdaS_antitoxin PF15943.5 KFQ99015.1 - 0.033 14.1 0.1 0.055 13.3 0.1 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_28 PF13518.6 KFQ99015.1 - 0.12 12.5 0.1 0.3 11.2 0.1 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain MerR_1 PF13411.6 KFQ99015.1 - 0.13 12.4 0.0 0.83 9.8 0.0 2.2 2 0 0 2 2 2 0 MerR HTH family regulatory protein Homeodomain PF00046.29 KFQ99016.1 - 3.3e-21 74.9 5.1 5.5e-21 74.2 5.1 1.4 1 0 0 1 1 1 1 Homeodomain Pro-kuma_activ PF09286.11 KFQ99016.1 - 0.003 17.8 0.2 0.0064 16.8 0.2 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Homez PF11569.8 KFQ99016.1 - 0.007 15.8 0.4 0.017 14.6 0.4 1.6 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 KFQ99016.1 - 0.0095 15.8 6.8 0.036 14.0 4.8 2.9 2 1 0 2 2 2 1 Homeobox KN domain YdaS_antitoxin PF15943.5 KFQ99016.1 - 0.045 13.6 0.1 0.089 12.7 0.1 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT APOBEC4 PF18775.1 KFQ99017.1 - 2.2e-28 98.2 0.8 2.4e-28 98.1 0.8 1.0 1 0 0 1 1 1 1 APOBEC4 NAD1 PF18778.1 KFQ99017.1 - 4e-21 75.9 0.6 4.3e-21 75.8 0.6 1.0 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 SNAD4 PF18750.1 KFQ99017.1 - 1.5e-20 73.4 0.6 1.7e-20 73.3 0.6 1.0 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC1 PF18769.1 KFQ99017.1 - 2.9e-19 69.2 0.1 3.1e-19 69.1 0.1 1.0 1 0 0 1 1 1 1 APOBEC1 APOBEC4_like PF18774.1 KFQ99017.1 - 4.5e-18 65.4 0.5 4.9e-18 65.3 0.5 1.0 1 0 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase APOBEC2 PF18772.1 KFQ99017.1 - 3.6e-17 63.0 0.3 3.8e-17 62.9 0.3 1.0 1 0 0 1 1 1 1 APOBEC2 APOBEC_N PF08210.11 KFQ99017.1 - 2.6e-14 53.5 0.5 2.8e-14 53.4 0.5 1.0 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC3 PF18771.1 KFQ99017.1 - 1e-13 51.6 0.4 1.1e-13 51.5 0.4 1.0 1 0 0 1 1 1 1 APOBEC3 NAD2 PF18782.1 KFQ99017.1 - 1.2e-13 51.6 0.2 1.2e-13 51.5 0.2 1.0 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC_C PF05240.14 KFQ99017.1 - 7.4e-07 29.0 0.0 9.2e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like C-terminal domain AID PF18767.1 KFQ99017.1 - 0.017 15.1 0.1 0.022 14.8 0.1 1.1 1 0 0 1 1 1 0 Activation induced deaminase APOBEC4_like PF18774.1 KFQ99018.1 - 6.6e-56 187.9 0.6 7.6e-56 187.7 0.6 1.0 1 0 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase APOBEC1 PF18769.1 KFQ99018.1 - 4.9e-50 167.9 1.4 6.9e-50 167.5 1.4 1.2 1 0 0 1 1 1 1 APOBEC1 SNAD4 PF18750.1 KFQ99018.1 - 1.8e-37 127.9 0.6 2.2e-37 127.7 0.6 1.1 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 KFQ99018.1 - 6.1e-34 117.6 0.9 6.7e-34 117.5 0.9 1.0 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 KFQ99018.1 - 5.5e-28 98.2 0.5 6.1e-28 98.0 0.5 1.0 1 0 0 1 1 1 1 APOBEC2 NAD2 PF18782.1 KFQ99018.1 - 3.3e-24 85.9 1.6 3.9e-24 85.7 1.6 1.0 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC4 PF18775.1 KFQ99018.1 - 7.6e-24 83.7 0.5 2.1e-23 82.2 0.1 1.9 2 0 0 2 2 2 1 APOBEC4 APOBEC_N PF08210.11 KFQ99018.1 - 1.8e-22 80.1 0.4 2e-22 79.9 0.4 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC3 PF18771.1 KFQ99018.1 - 9.9e-22 77.5 0.5 1.1e-21 77.4 0.5 1.0 1 0 0 1 1 1 1 APOBEC3 APOBEC_C PF05240.14 KFQ99018.1 - 1.7e-15 56.7 1.5 2.1e-15 56.4 0.1 1.8 2 0 0 2 2 2 1 APOBEC-like C-terminal domain dCMP_cyt_deam_1 PF00383.23 KFQ99018.1 - 0.00014 21.7 0.3 0.00023 21.0 0.3 1.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AID PF18767.1 KFQ99018.1 - 0.02 14.9 0.0 0.1 12.6 0.0 1.9 1 1 1 2 2 2 0 Activation induced deaminase MafB19-deam PF14437.6 KFQ99018.1 - 0.024 14.4 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 MafB19-like deaminase APOBEC2 PF18772.1 KFQ99019.1 - 8.9e-70 234.3 1.5 1e-69 234.1 1.5 1.0 1 0 0 1 1 1 1 APOBEC2 NAD1 PF18778.1 KFQ99019.1 - 2.9e-68 229.4 1.3 3.3e-68 229.2 1.3 1.0 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 KFQ99019.1 - 1.4e-60 204.3 0.7 1.6e-60 204.1 0.7 1.0 1 0 0 1 1 1 1 APOBEC-like N-terminal domain NAD2 PF18782.1 KFQ99019.1 - 1.8e-58 197.6 4.7 2.1e-58 197.4 4.7 1.0 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 SNAD4 PF18750.1 KFQ99019.1 - 6.3e-37 126.2 0.1 8.7e-37 125.7 0.1 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 KFQ99019.1 - 3e-35 121.3 0.2 3.9e-35 121.0 0.2 1.1 1 0 0 1 1 1 1 APOBEC3 APOBEC_C PF05240.14 KFQ99019.1 - 2.6e-29 101.0 0.1 4.5e-29 100.2 0.1 1.4 1 0 0 1 1 1 1 APOBEC-like C-terminal domain APOBEC4_like PF18774.1 KFQ99019.1 - 2.1e-25 89.2 0.2 2.7e-25 88.8 0.2 1.2 1 0 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase APOBEC4 PF18775.1 KFQ99019.1 - 2.7e-21 75.5 0.0 4.4e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 APOBEC4 APOBEC1 PF18769.1 KFQ99019.1 - 3e-19 69.2 0.0 4.5e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 APOBEC1 DUF2599 PF10783.9 KFQ99019.1 - 0.057 14.1 0.1 0.43 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2599) Toxin-deaminase PF14424.6 KFQ99019.1 - 0.065 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases RcbX PF02341.15 KFQ99019.1 - 0.09 13.0 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 RbcX protein MAGP PF05507.11 KFQ99020.1 - 2.5e-29 102.4 9.6 3.7e-29 101.8 9.6 1.3 1 0 0 1 1 1 1 Microfibril-associated glycoprotein (MAGP) SVWC PF15430.6 KFQ99020.1 - 0.028 14.7 3.5 0.11 12.7 0.2 2.4 1 1 1 2 2 2 0 Single domain von Willebrand factor type C RimK PF08443.11 KFQ99021.1 - 1.2e-42 145.6 0.0 2.1e-42 144.8 0.0 1.4 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GSH-S_ATP PF02955.16 KFQ99021.1 - 1.1e-11 44.4 0.0 1.8e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_ST PF14397.6 KFQ99021.1 - 6.3e-08 32.2 1.7 0.0054 16.0 0.4 3.1 1 1 1 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 KFQ99021.1 - 1.1e-07 32.0 0.0 1.6e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Synapsin_C PF02750.14 KFQ99021.1 - 0.00019 21.0 0.0 0.00028 20.5 0.0 1.2 1 0 0 1 1 1 1 Synapsin, ATP binding domain Rimk_N PF18030.1 KFQ99021.1 - 0.00028 21.2 0.0 0.0005 20.4 0.0 1.4 1 0 0 1 1 1 1 RimK PreATP-grasp domain ATP-grasp PF02222.22 KFQ99021.1 - 0.0012 18.5 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_YheCD PF14398.6 KFQ99021.1 - 0.0012 18.1 0.0 0.91 8.7 0.0 3.1 1 1 1 2 2 2 2 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.13 KFQ99021.1 - 0.0057 16.2 0.0 0.03 13.9 0.0 1.9 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 KFQ99021.1 - 0.042 13.3 0.0 0.21 11.0 0.0 2.0 1 1 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain TED_complement PF07678.14 KFQ99024.1 - 4e-100 334.9 0.9 6.4e-100 334.2 0.9 1.3 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_BRD PF07703.14 KFQ99024.1 - 1.7e-19 70.5 0.0 5.5e-19 68.9 0.0 2.0 2 0 0 2 2 2 1 Alpha-2-macroglobulin bait region domain A2M PF00207.22 KFQ99024.1 - 2.8e-18 65.5 0.8 7.3e-18 64.2 0.1 2.2 2 0 0 2 2 2 1 Alpha-2-macroglobulin family A2M_recep PF07677.14 KFQ99024.1 - 1.9e-16 60.5 0.0 6.6e-16 58.8 0.0 2.0 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain SVA PF05326.11 KFQ99024.1 - 3.2e-05 23.9 0.7 0.00052 20.0 0.8 2.4 2 0 0 2 2 2 1 Seminal vesicle autoantigen (SVA) Prenyltrans PF00432.21 KFQ99024.1 - 0.17 11.7 0.0 1.6 8.5 0.0 2.6 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat PHC2_SAM_assoc PF16616.5 KFQ99025.1 - 2e-28 99.6 4.6 2e-28 99.6 4.6 5.7 5 2 1 6 6 6 1 Unstructured region on Polyhomeotic-like protein 1 and 2 SAM_1 PF00536.30 KFQ99025.1 - 1.4e-16 60.7 0.0 2.8e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFQ99025.1 - 6.3e-10 39.0 0.0 1.2e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFQ99025.1 - 0.0044 17.0 0.0 0.0098 15.8 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain zf-FCS PF06467.14 KFQ99025.1 - 0.2 11.6 4.4 0.85 9.6 4.4 2.1 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-CGNR PF11706.8 KFQ99025.1 - 0.3 11.0 3.6 0.69 9.8 3.6 1.5 1 0 0 1 1 1 0 CGNR zinc finger Man-6-P_recep PF02157.15 KFQ99026.1 - 1.6e-127 423.8 0.0 1.9e-127 423.6 0.0 1.0 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 KFQ99026.1 - 2e-13 50.8 0.1 3.5e-13 50.0 0.1 1.4 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 KFQ99026.1 - 0.0001 22.4 0.1 0.02 15.0 0.0 2.1 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.6 KFQ99026.1 - 0.042 13.5 0.1 0.059 13.0 0.1 1.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein TED_complement PF07678.14 KFQ99027.1 - 2.2e-109 365.3 0.0 3.5e-109 364.6 0.0 1.3 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_BRD PF07703.14 KFQ99027.1 - 4.5e-33 114.6 0.6 2.8e-30 105.5 0.1 3.0 2 0 0 2 2 2 2 Alpha-2-macroglobulin bait region domain A2M PF00207.22 KFQ99027.1 - 1.2e-28 98.8 1.2 2.3e-28 97.9 0.2 2.1 2 0 0 2 2 2 1 Alpha-2-macroglobulin family MG3 PF17791.1 KFQ99027.1 - 7.4e-25 87.0 3.4 1.7e-24 85.9 0.7 2.9 3 0 0 3 3 3 1 Macroglobulin domain MG3 MG4 PF17789.1 KFQ99027.1 - 1.3e-21 76.6 0.0 8.6e-21 73.9 0.0 2.5 2 0 0 2 2 2 1 Macroglobulin domain MG4 MG2 PF01835.19 KFQ99027.1 - 1.3e-14 54.4 0.0 5.7e-14 52.3 0.0 2.2 2 0 0 2 2 2 1 MG2 domain Big_1 PF02369.16 KFQ99027.1 - 5.1e-05 23.2 0.3 0.00034 20.6 0.3 2.5 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 1) SVA PF05326.11 KFQ99027.1 - 0.00064 19.7 0.0 0.0036 17.3 0.0 2.2 2 0 0 2 2 2 1 Seminal vesicle autoantigen (SVA) CarboxypepD_reg PF13620.6 KFQ99027.1 - 0.0013 19.0 2.7 0.0075 16.5 0.3 3.0 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain Invasin_D3 PF09134.10 KFQ99027.1 - 0.11 12.8 0.2 0.46 10.8 0.2 2.0 1 0 0 1 1 1 0 Invasin, domain 3 DUF4773 PF15998.5 KFQ99027.1 - 0.81 10.2 2.6 1.2 9.7 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4773) TED_complement PF07678.14 KFQ99028.1 - 5.1e-107 357.5 0.2 7.4e-107 357.0 0.2 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_BRD PF07703.14 KFQ99028.1 - 3.7e-34 118.1 2.2 1.5e-30 106.4 0.0 3.1 3 0 0 3 3 3 2 Alpha-2-macroglobulin bait region domain A2M PF00207.22 KFQ99028.1 - 1.5e-28 98.5 0.3 4.9e-28 96.8 0.0 2.1 2 0 0 2 2 2 1 Alpha-2-macroglobulin family MG3 PF17791.1 KFQ99028.1 - 4.1e-26 91.1 6.2 3.7e-25 88.0 1.0 3.9 4 0 0 4 4 4 1 Macroglobulin domain MG3 A2M_recep PF07677.14 KFQ99028.1 - 3.6e-24 85.3 1.6 1.2e-23 83.6 1.6 2.0 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain MG2 PF01835.19 KFQ99028.1 - 1.6e-18 66.9 0.0 6.8e-18 64.9 0.0 2.2 1 0 0 1 1 1 1 MG2 domain MG4 PF17789.1 KFQ99028.1 - 6.1e-18 64.8 0.0 2.3e-17 62.9 0.0 2.1 1 0 0 1 1 1 1 Macroglobulin domain MG4 SQHop_cyclase_C PF13243.6 KFQ99028.1 - 4.5e-06 26.0 0.1 0.0056 15.8 0.2 2.2 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain MG1 PF17790.1 KFQ99028.1 - 0.00028 21.3 0.5 0.0052 17.2 0.0 3.1 3 0 0 3 3 3 1 Macroglobulin domain MG1 SVA PF05326.11 KFQ99028.1 - 0.035 14.1 0.0 0.093 12.7 0.0 1.7 1 0 0 1 1 1 0 Seminal vesicle autoantigen (SVA) Prenyltrans PF00432.21 KFQ99028.1 - 0.066 13.0 0.2 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat Big_1 PF02369.16 KFQ99028.1 - 0.11 12.5 0.1 0.57 10.2 0.1 2.3 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) Band_7 PF01145.25 KFQ99049.1 - 8.8e-18 64.9 0.0 8.8e-18 64.9 0.0 1.8 1 1 1 2 2 2 1 SPFH domain / Band 7 family DUF4769 PF15992.5 KFQ99049.1 - 0.0084 15.9 0.3 0.011 15.5 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4769) Band_7_1 PF13421.6 KFQ99049.1 - 0.034 13.9 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family Phosphodiest PF01663.22 KFQ99050.1 - 6.1e-13 49.1 0.1 9.1e-13 48.5 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.12 KFQ99050.1 - 0.021 14.9 0.1 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 PglZ domain AAA PF00004.29 KFQ99051.1 - 1.4e-93 310.3 0.0 1.5e-46 158.1 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFQ99051.1 - 4.7e-25 87.1 4.6 3.5e-13 49.1 0.2 3.0 3 0 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 KFQ99051.1 - 3.7e-22 78.3 1.7 1.1e-21 76.8 0.6 2.4 3 0 0 3 3 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KFQ99051.1 - 4.2e-14 52.6 0.0 1.5e-05 24.8 0.0 3.4 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFQ99051.1 - 5.6e-14 52.9 1.7 4.8e-05 23.8 0.1 4.6 3 2 1 4 4 4 2 AAA ATPase domain CDC48_2 PF02933.17 KFQ99051.1 - 8.1e-13 48.0 0.0 1.8e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.6 KFQ99051.1 - 4.5e-11 43.1 0.0 2.7e-05 24.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 KFQ99051.1 - 1.3e-10 41.7 0.0 3.5e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KFQ99051.1 - 1.4e-10 41.3 0.4 4.1e-05 23.6 0.0 3.4 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFQ99051.1 - 1.5e-09 38.3 1.2 0.012 15.9 0.1 4.2 3 2 1 4 4 3 2 AAA domain TIP49 PF06068.13 KFQ99051.1 - 6.1e-09 35.5 0.1 0.0011 18.3 0.0 2.7 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_18 PF13238.6 KFQ99051.1 - 6.7e-08 33.2 0.0 0.012 16.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KFQ99051.1 - 1.3e-07 32.0 0.0 0.0058 17.0 0.0 3.2 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.21 KFQ99051.1 - 2.7e-07 30.2 0.2 0.017 14.5 0.0 2.6 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KFQ99051.1 - 3.6e-07 30.3 0.0 0.02 14.9 0.0 2.7 3 0 0 3 3 2 2 AAA domain ATPase PF06745.13 KFQ99051.1 - 4.2e-07 29.6 0.1 0.42 9.9 0.0 3.4 3 0 0 3 3 3 3 KaiC IstB_IS21 PF01695.17 KFQ99051.1 - 4.4e-07 29.8 0.1 0.047 13.4 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Parvo_NS1 PF01057.17 KFQ99051.1 - 2.6e-06 26.7 0.1 0.031 13.4 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KFQ99051.1 - 3.6e-06 27.3 0.0 0.16 12.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 KFQ99051.1 - 5.5e-06 26.0 0.0 0.061 12.8 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 KFQ99051.1 - 5.8e-06 26.4 0.6 0.22 11.4 0.0 3.9 3 2 1 4 4 3 2 ATPase domain predominantly from Archaea ABC_tran PF00005.27 KFQ99051.1 - 7.4e-06 26.5 0.0 0.0088 16.6 0.0 3.4 3 1 0 3 3 2 1 ABC transporter DUF815 PF05673.13 KFQ99051.1 - 9.9e-06 24.9 0.0 0.01 15.0 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_25 PF13481.6 KFQ99051.1 - 1e-05 25.2 2.3 1.4 8.4 0.1 3.6 2 2 0 3 3 3 2 AAA domain AAA_24 PF13479.6 KFQ99051.1 - 3.1e-05 23.8 0.0 0.074 12.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain TsaE PF02367.17 KFQ99051.1 - 4.9e-05 23.3 0.0 0.26 11.3 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 KFQ99051.1 - 5.8e-05 23.0 0.0 0.0016 18.2 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 KFQ99051.1 - 6.4e-05 23.4 0.0 0.82 10.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.26 KFQ99051.1 - 6.9e-05 22.6 0.0 0.37 10.5 0.0 3.0 2 2 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.12 KFQ99051.1 - 8.1e-05 22.6 0.1 0.3 11.0 0.0 3.6 3 1 0 4 4 4 1 NACHT domain NB-ARC PF00931.22 KFQ99051.1 - 0.00027 20.2 0.0 0.19 10.9 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain DUF2075 PF09848.9 KFQ99051.1 - 0.00034 20.0 0.0 0.34 10.1 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 KFQ99051.1 - 0.00044 19.6 0.0 0.46 9.7 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin Bac_DnaA PF00308.18 KFQ99051.1 - 0.00048 20.0 0.0 0.82 9.5 0.0 3.1 4 0 0 4 4 2 1 Bacterial dnaA protein AAA_3 PF07726.11 KFQ99051.1 - 0.00058 19.7 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 KFQ99051.1 - 0.00059 19.9 0.0 0.069 13.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KFQ99051.1 - 0.00087 18.8 0.4 1.5 8.2 0.1 2.5 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activ_2 PF14532.6 KFQ99051.1 - 0.00094 19.3 0.0 2.2 8.4 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_11 PF13086.6 KFQ99051.1 - 0.0023 17.8 0.0 2 8.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KFQ99051.1 - 0.0036 17.2 0.0 0.89 9.4 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_19 PF13245.6 KFQ99051.1 - 0.0044 17.4 2.0 2.8 8.3 0.2 3.4 3 1 0 4 4 2 1 AAA domain AAA_30 PF13604.6 KFQ99051.1 - 0.017 14.8 0.4 2.6 7.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain UFD1 PF03152.14 KFQ99051.1 - 0.02 14.4 0.0 0.048 13.1 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 SKI PF01202.22 KFQ99051.1 - 0.027 14.6 0.0 5 7.2 0.0 2.8 2 0 0 2 2 2 0 Shikimate kinase NTPase_1 PF03266.15 KFQ99051.1 - 0.027 14.4 0.2 4.7 7.1 0.0 3.1 3 0 0 3 3 3 0 NTPase Cytidylate_kin PF02224.18 KFQ99051.1 - 0.04 13.6 0.0 8.4 6.1 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase T2SSE PF00437.20 KFQ99051.1 - 0.062 12.3 0.0 9.2 5.2 0.0 2.9 2 1 0 2 2 2 0 Type II/IV secretion system protein Zot PF05707.12 KFQ99051.1 - 0.074 12.7 0.0 1.2 8.7 0.0 2.6 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) PduV-EutP PF10662.9 KFQ99051.1 - 0.1 12.4 0.0 2.9 7.6 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 KFQ99051.1 - 0.11 11.9 0.0 11 5.3 0.0 2.9 3 0 0 3 3 2 0 Bacterial TniB protein KAP_NTPase PF07693.14 KFQ99051.1 - 0.11 11.7 0.1 3.5 6.8 0.0 2.8 2 2 1 3 3 3 0 KAP family P-loop domain AAA_6 PF12774.7 KFQ99051.1 - 0.15 11.0 1.6 11 4.9 0.0 2.9 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region AAA_23 PF13476.6 KFQ99051.1 - 0.2 12.1 0.1 13 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Keratin PF02422.16 KFQ99054.1 - 3.8e-25 87.4 11.3 4.1e-25 87.3 11.3 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFQ99055.1 - 3.2e-34 116.5 20.5 1.1e-32 111.6 20.5 2.0 1 1 0 1 1 1 1 Keratin DUF3432 PF11914.8 KFQ99055.1 - 0.29 11.4 6.3 0.48 10.7 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Vanabin-2 PF11437.8 KFQ99055.1 - 0.33 11.1 5.1 0.42 10.8 5.1 1.1 1 0 0 1 1 1 0 Vanadium-binding protein 2 Keratin PF02422.16 KFQ99056.1 - 6.6e-37 125.1 12.1 7.3e-37 125.0 12.1 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFQ99057.1 - 2.3e-38 129.8 15.5 2.6e-38 129.6 15.5 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFQ99058.1 - 7.2e-35 118.6 13.1 7.8e-35 118.5 13.1 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFQ99059.1 - 8e-37 124.8 15.4 8.9e-37 124.7 15.4 1.0 1 0 0 1 1 1 1 Keratin Ricin_B_lectin PF00652.22 KFQ99064.1 - 2.6e-09 37.4 6.0 4e-06 27.1 2.0 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 KFQ99064.1 - 0.0019 17.8 1.1 0.012 15.2 1.1 1.9 1 1 0 1 1 1 1 Cytolethal distending toxin A/C domain ChuX_HutX PF06228.13 KFQ99064.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Haem utilisation ChuX/HutX Sema PF01403.19 KFQ99098.1 - 7.7e-164 545.5 0.0 3.1e-162 540.2 0.0 2.1 1 1 1 2 2 2 2 Sema domain V-set PF07686.17 KFQ99098.1 - 0.00077 19.6 0.1 0.051 13.7 0.1 2.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFQ99098.1 - 0.0011 19.5 0.0 0.0027 18.3 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ99098.1 - 0.0012 18.9 0.0 0.0026 17.8 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain PSI PF01437.25 KFQ99098.1 - 0.0012 19.3 8.8 0.0028 18.2 8.8 1.6 1 0 0 1 1 1 1 Plexin repeat ig PF00047.25 KFQ99098.1 - 0.0018 18.4 0.0 0.0046 17.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 KFQ99098.1 - 0.0052 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFQ99098.1 - 0.008 16.5 0.0 0.045 14.1 0.0 2.3 3 0 0 3 3 3 1 Immunoglobulin domain ANF_receptor PF01094.28 KFQ99099.1 - 3.7e-104 348.6 0.1 4.7e-104 348.3 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 KFQ99099.1 - 1.6e-66 224.4 23.5 2.9e-66 223.6 23.5 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 KFQ99099.1 - 2.4e-13 49.8 12.2 6.4e-13 48.5 12.2 1.8 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.6 KFQ99099.1 - 6.1e-09 36.0 0.0 1.1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein DDE_Tnp_IS1 PF03400.13 KFQ99099.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 IS1 transposase Ephrin_rec_like PF07699.13 KFQ99100.1 - 3.7e-09 36.2 84.6 0.00046 19.9 7.2 8.9 6 3 3 9 9 9 7 Putative ephrin-receptor like NCD3G PF07562.14 KFQ99100.1 - 0.14 12.1 68.7 0.12 12.3 5.0 7.9 7 1 0 7 7 7 0 Nine Cysteines Domain of family 3 GPCR Myb_DNA-binding PF00249.31 KFQ99101.1 - 1.5e-31 108.3 13.7 8.3e-20 70.7 0.7 4.4 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFQ99101.1 - 4.7e-15 55.6 5.7 1.4e-08 34.9 0.1 4.5 2 1 2 4 4 4 2 Myb-like DNA-binding domain DUF5591 PF17884.1 KFQ99101.1 - 0.0068 16.3 0.4 4 7.3 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF5591) DUF3818 PF12825.7 KFQ99101.1 - 0.016 14.3 1.6 0.033 13.2 1.6 1.5 1 1 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Myb_DNA-bind_4 PF13837.6 KFQ99101.1 - 1.4 9.3 8.8 0.13 12.6 0.4 3.4 4 1 0 4 4 4 0 Myb/SANT-like DNA-binding domain DUF2678 PF10856.8 KFQ99102.1 - 6.2e-51 171.3 5.8 6.8e-51 171.2 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) Polysacc_synt_C PF14667.6 KFQ99102.1 - 2.6e-06 27.5 2.2 3.1e-06 27.3 2.2 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis C-terminal domain DUF2417 PF10329.9 KFQ99102.1 - 0.038 13.4 8.0 0.082 12.3 8.0 1.5 1 1 0 1 1 1 0 Region of unknown function (DUF2417) Intg_mem_TP0381 PF09529.10 KFQ99102.1 - 0.06 12.9 6.7 0.073 12.6 6.7 1.1 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) 7TMR-DISM_7TM PF07695.11 KFQ99102.1 - 1.1 9.1 12.0 5.4 6.9 12.1 1.7 1 1 0 1 1 1 0 7TM diverse intracellular signalling COPI_assoc PF08507.10 KFQ99102.1 - 1.1 9.3 12.3 0.22 11.6 6.0 2.0 1 1 1 2 2 2 0 COPI associated protein DUF4131 PF13567.6 KFQ99102.1 - 7 6.3 6.2 2.5 7.7 2.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Meiosis_expr PF15163.6 KFQ99103.1 - 6.3e-38 129.3 10.5 7.4e-38 129.1 10.5 1.1 1 0 0 1 1 1 1 Meiosis-expressed POTRA PF07244.15 KFQ99103.1 - 0.024 15.2 0.2 0.042 14.4 0.2 1.4 1 0 0 1 1 1 0 Surface antigen variable number repeat DRMBL PF07522.14 KFQ99104.1 - 1.3e-18 67.2 0.0 2.6e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KFQ99104.1 - 0.0027 17.2 0.0 0.0049 16.4 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.12 KFQ99104.1 - 0.0098 15.8 0.0 0.025 14.5 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 KFQ99104.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily SET PF00856.28 KFQ99105.1 - 7.1e-22 78.6 0.2 2.3e-21 76.9 0.1 1.9 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 KFQ99105.1 - 1.2e-16 61.3 4.1 1.2e-16 61.3 4.1 2.7 3 0 0 3 3 3 1 Pre-SET motif Chromo PF00385.24 KFQ99105.1 - 1.5e-14 53.7 1.5 2.9e-14 52.7 1.5 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AWS PF17907.1 KFQ99105.1 - 0.0079 16.2 1.6 0.0079 16.2 1.6 3.4 3 0 0 3 3 3 1 AWS domain IGPS PF00218.21 KFQ99105.1 - 0.16 11.1 0.0 0.47 9.6 0.0 1.7 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase HSP70 PF00012.20 KFQ99106.1 - 1.2e-109 367.2 0.1 1.4e-109 367.0 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFQ99106.1 - 4.9e-11 42.0 0.3 1.2e-10 40.7 0.0 1.7 2 0 0 2 2 2 1 MreB/Mbl protein DUF1151 PF06625.11 KFQ99108.1 - 2.6e-43 146.6 23.6 3.1e-43 146.3 23.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1151) DUF3338 PF11819.8 KFQ99111.1 - 2.4e-59 199.2 6.0 2.4e-59 199.2 6.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3338) FERM_C PF09380.10 KFQ99111.1 - 8.1e-24 83.8 0.4 1.8e-23 82.7 0.4 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 KFQ99111.1 - 3.2e-20 72.7 4.3 3.4e-20 72.6 0.0 2.9 3 0 0 3 3 3 1 FERM central domain FERM_N PF09379.10 KFQ99111.1 - 3.5e-09 36.5 0.1 9.6e-09 35.1 0.1 1.7 1 0 0 1 1 1 1 FERM N-terminal domain Prp18 PF02840.15 KFQ99112.1 - 1.3e-62 210.0 0.1 2.5e-62 209.2 0.1 1.5 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.11 KFQ99112.1 - 1.2e-13 50.3 3.5 1.2e-13 50.3 3.5 2.1 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Phage_int_SAM_4 PF13495.6 KFQ99112.1 - 0.12 12.9 0.2 20 5.7 0.0 2.6 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain BEN PF10523.9 KFQ99113.1 - 8.1e-18 64.4 0.1 2.2e-17 63.1 0.1 1.8 1 0 0 1 1 1 1 BEN domain AIRS_C PF02769.22 KFQ99114.1 - 5.7e-31 107.8 0.1 8.5e-31 107.2 0.1 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 KFQ99114.1 - 9.6e-11 42.2 0.2 2.5e-10 40.9 0.2 1.7 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain PhyH PF05721.13 KFQ99115.1 - 1.7e-42 146.1 0.0 2.1e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PhyH PF05721.13 KFQ99116.1 - 2.4e-05 24.7 0.0 2.8e-05 24.5 0.0 1.0 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Mcm10 PF09332.11 KFQ99117.1 - 5.2e-150 499.8 10.5 5.2e-150 499.8 10.5 3.0 3 1 1 4 4 4 1 Mcm10 replication factor zf-primase PF09329.11 KFQ99117.1 - 1.6e-17 63.0 1.9 4.8e-17 61.5 1.9 1.9 1 0 0 1 1 1 1 Primase zinc finger DUF3138 PF11336.8 KFQ99117.1 - 0.11 11.1 0.2 0.22 10.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ribosomal_L29 PF00831.23 KFQ99117.1 - 1.1 9.3 9.7 2.5 8.1 3.6 3.2 2 0 0 2 2 2 0 Ribosomal L29 protein SlyX PF04102.12 KFQ99117.1 - 3.2 8.4 9.1 0.5 11.0 1.7 3.5 3 0 0 3 3 3 0 SlyX NEMO PF11577.8 KFQ99118.1 - 2.7e-30 104.2 14.1 2.7e-30 104.2 14.1 5.9 6 0 0 6 6 6 1 NF-kappa-B essential modulator NEMO CC2-LZ PF16516.5 KFQ99118.1 - 7.8e-30 103.2 15.4 7.8e-30 103.2 15.4 5.8 3 2 1 5 5 5 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator zf_C2H2_10 PF18414.1 KFQ99118.1 - 6.9e-16 57.5 5.5 1.5e-15 56.3 5.5 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger MLD PF11647.8 KFQ99118.1 - 0.02 15.1 3.3 3.7 7.9 0.0 3.8 2 1 1 3 3 3 0 Membrane Localization Domain HHA PF05321.11 KFQ99118.1 - 0.67 10.3 3.8 1.9 8.8 0.1 3.5 3 0 0 3 3 3 0 Haemolysin expression modulating protein SAG PF04092.13 KFQ99118.1 - 4.2 8.2 9.2 1.3 9.8 1.0 2.9 2 0 0 2 2 2 0 SRS domain YscO PF07321.12 KFQ99120.1 - 2.8e-06 27.3 8.5 4.3e-06 26.7 8.5 1.2 1 0 0 1 1 1 1 Type III secretion protein YscO DUF812 PF05667.11 KFQ99120.1 - 0.00027 20.0 4.0 0.00035 19.6 4.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) bZIP_1 PF00170.21 KFQ99120.1 - 0.00049 20.1 3.6 0.00049 20.1 3.6 1.8 1 1 1 2 2 2 1 bZIP transcription factor ATG16 PF08614.11 KFQ99120.1 - 0.00053 20.3 5.2 0.00061 20.1 5.2 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 KFQ99120.1 - 0.00097 19.3 2.8 0.0014 18.8 2.8 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family KLRAQ PF10205.9 KFQ99120.1 - 0.0012 19.1 8.4 0.0018 18.5 8.4 1.3 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein DUF3450 PF11932.8 KFQ99120.1 - 0.0018 17.6 2.9 0.0021 17.4 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Tropomyosin_1 PF12718.7 KFQ99120.1 - 0.0029 17.7 8.8 0.0039 17.4 8.8 1.1 1 0 0 1 1 1 1 Tropomyosin like DUF1664 PF07889.12 KFQ99120.1 - 0.0035 17.4 3.5 0.0049 16.9 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KFQ99120.1 - 0.0041 17.5 2.3 0.0054 17.1 1.1 1.8 1 1 1 2 2 2 1 Flagella accessory protein C (FlaC) TMCO5 PF14992.6 KFQ99120.1 - 0.0042 16.7 4.0 0.0052 16.4 4.0 1.1 1 0 0 1 1 1 1 TMCO5 family DegS PF05384.11 KFQ99120.1 - 0.0059 16.1 3.9 0.0095 15.4 3.9 1.3 1 0 0 1 1 1 1 Sensor protein DegS BLOC1_2 PF10046.9 KFQ99120.1 - 0.007 16.6 1.9 0.012 15.8 1.9 1.4 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF489 PF04356.12 KFQ99120.1 - 0.0094 16.0 1.4 0.012 15.6 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF489) Ax_dynein_light PF10211.9 KFQ99120.1 - 0.011 15.6 8.6 0.015 15.2 8.6 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain Herpes_UL6 PF01763.16 KFQ99120.1 - 0.014 13.9 2.8 0.015 13.8 2.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like UPF0242 PF06785.11 KFQ99120.1 - 0.017 15.2 3.0 0.021 14.9 3.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Occludin_ELL PF07303.13 KFQ99120.1 - 0.019 15.7 4.6 0.029 15.1 4.6 1.3 1 0 0 1 1 1 0 Occludin homology domain Prominin PF05478.11 KFQ99120.1 - 0.021 12.8 1.3 0.022 12.7 1.3 1.1 1 0 0 1 1 1 0 Prominin Laminin_II PF06009.12 KFQ99120.1 - 0.022 14.7 4.1 0.031 14.3 4.1 1.1 1 0 0 1 1 1 0 Laminin Domain II ZapB PF06005.12 KFQ99120.1 - 0.025 15.0 8.7 0.042 14.3 8.7 1.4 1 0 0 1 1 1 0 Cell division protein ZapB PRKCSH-like PF12999.7 KFQ99120.1 - 0.028 14.2 1.3 0.033 14.0 1.3 1.1 1 0 0 1 1 1 0 Glucosidase II beta subunit-like LMBR1 PF04791.16 KFQ99120.1 - 0.032 13.1 0.5 0.029 13.3 0.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Uso1_p115_C PF04871.13 KFQ99120.1 - 0.034 14.5 5.8 0.052 13.9 5.8 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region TMPIT PF07851.13 KFQ99120.1 - 0.034 13.4 2.3 0.037 13.3 2.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF745 PF05335.13 KFQ99120.1 - 0.034 13.9 2.8 0.045 13.5 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DivIC PF04977.15 KFQ99120.1 - 0.037 13.8 7.5 0.064 13.0 7.5 1.4 1 0 0 1 1 1 0 Septum formation initiator NPV_P10 PF05531.12 KFQ99120.1 - 0.037 14.5 2.9 0.97 9.9 0.2 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TMF_DNA_bd PF12329.8 KFQ99120.1 - 0.051 13.6 9.4 0.08 13.0 9.4 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF4988 PF16378.5 KFQ99120.1 - 0.054 13.2 0.6 0.078 12.6 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function Rho_Binding PF08912.11 KFQ99120.1 - 0.054 14.3 5.3 0.054 14.3 5.3 1.6 1 1 0 1 1 1 0 Rho Binding DUF3552 PF12072.8 KFQ99120.1 - 0.059 12.8 8.7 0.073 12.5 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Atg14 PF10186.9 KFQ99120.1 - 0.072 12.2 6.7 0.081 12.0 6.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 P4Ha_N PF08336.11 KFQ99120.1 - 0.073 13.1 3.3 0.12 12.4 3.3 1.3 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF3251 PF11622.8 KFQ99120.1 - 0.082 12.5 1.4 0.13 11.9 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) GrpE PF01025.19 KFQ99120.1 - 0.082 12.6 5.7 0.11 12.1 5.7 1.2 1 0 0 1 1 1 0 GrpE SlyX PF04102.12 KFQ99120.1 - 0.096 13.3 4.7 0.25 12.0 4.7 1.7 1 1 0 1 1 1 0 SlyX XhlA PF10779.9 KFQ99120.1 - 0.13 12.4 4.2 0.2 11.9 3.6 1.6 1 1 1 2 2 2 0 Haemolysin XhlA GIT_CC PF16559.5 KFQ99120.1 - 0.14 12.0 10.2 0.36 10.7 2.1 2.5 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 KFQ99120.1 - 0.16 12.6 5.5 0.26 11.9 5.5 1.4 1 0 0 1 1 1 0 Initiation control protein YabA DUF773 PF05600.12 KFQ99120.1 - 0.18 10.5 9.1 0.23 10.1 9.1 1.1 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 Exonuc_VII_L PF02601.15 KFQ99120.1 - 0.2 11.2 5.5 0.23 11.0 5.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ADIP PF11559.8 KFQ99120.1 - 0.22 11.6 11.5 0.32 11.1 11.5 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4446 PF14584.6 KFQ99120.1 - 0.31 11.0 3.6 0.58 10.1 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) TFR_dimer PF04253.15 KFQ99120.1 - 0.47 10.6 3.8 1.7 8.7 2.9 1.9 1 1 1 2 2 2 0 Transferrin receptor-like dimerisation domain Pkinase PF00069.25 KFQ99121.1 - 2.4e-77 259.9 0.0 2.9e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ99121.1 - 2.9e-35 121.8 0.0 3.6e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ99121.1 - 4.6e-09 36.0 0.0 5.8e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFQ99121.1 - 0.00015 21.2 0.1 0.00029 20.3 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFQ99121.1 - 0.00017 20.5 0.0 0.00032 19.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KFQ99121.1 - 0.0011 18.6 0.1 0.0011 18.6 0.1 1.5 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KFQ99121.1 - 0.0014 18.6 0.0 0.2 11.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family 5_nucleotid PF05761.14 KFQ99121.1 - 0.037 12.9 0.1 0.06 12.3 0.1 1.2 1 0 0 1 1 1 0 5' nucleotidase family Pox_ser-thr_kin PF05445.11 KFQ99121.1 - 0.081 11.9 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase D123 PF07065.14 KFQ99123.1 - 3.9e-94 315.2 0.3 4.7e-94 315.0 0.3 1.0 1 0 0 1 1 1 1 D123 R2K_2 PF18299.1 KFQ99123.1 - 0.027 14.3 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 ATPgrasp_YheCD PF14398.6 KFQ99123.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 YheC/D like ATP-grasp SecY PF00344.20 KFQ99124.1 - 2.8e-75 253.4 10.8 3.7e-75 253.0 10.8 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KFQ99124.1 - 8.2e-19 67.2 0.2 2.4e-18 65.7 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p YlaH PF14036.6 KFQ99124.1 - 0.11 12.9 2.7 6.2 7.2 0.2 3.2 2 0 0 2 2 2 0 YlaH-like protein DUF2975 PF11188.8 KFQ99124.1 - 1 9.3 7.7 0.36 10.7 0.3 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF2975) Transket_pyr PF02779.24 KFQ99125.1 - 5.4e-63 211.9 0.0 9.4e-63 211.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KFQ99125.1 - 1.3e-46 158.9 0.0 2.6e-46 157.9 0.0 1.5 1 1 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KFQ99125.1 - 3.6e-46 156.6 0.0 6e-46 155.9 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal MIF4G PF02854.19 KFQ99127.1 - 4.8e-42 144.0 0.0 8.7e-42 143.1 0.0 1.5 1 0 0 1 1 1 1 MIF4G domain Upf2 PF04050.14 KFQ99127.1 - 1.1e-16 61.8 3.2 1.1e-16 61.8 3.2 2.6 1 1 1 2 2 2 1 Up-frameshift suppressor 2 CobT PF06213.12 KFQ99127.1 - 0.35 10.2 18.3 0.51 9.7 18.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.12 KFQ99127.1 - 0.38 8.9 24.3 0.48 8.6 24.3 1.1 1 0 0 1 1 1 0 Nop14-like family Raftlin PF15250.6 KFQ99127.1 - 0.41 9.4 4.7 0.52 9.0 4.7 1.1 1 0 0 1 1 1 0 Raftlin SDA1 PF05285.12 KFQ99127.1 - 0.45 9.9 20.8 0.59 9.5 20.8 1.1 1 0 0 1 1 1 0 SDA1 DUF913 PF06025.12 KFQ99127.1 - 1.4 7.8 4.0 2 7.3 4.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 KFQ99127.1 - 2.3 6.4 13.3 3 6.0 13.3 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 KFQ99127.1 - 2.7 7.2 17.9 3.6 6.8 17.9 1.1 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 KFQ99127.1 - 8.8 5.0 9.1 13 4.4 9.1 1.2 1 0 0 1 1 1 0 Presenilin SARG PF15385.6 KFQ99128.1 - 2.9e-16 59.9 33.9 4.5e-09 36.1 0.8 3.9 1 1 1 3 3 3 3 Specifically androgen-regulated gene protein ECH_1 PF00378.20 KFQ99129.1 - 4.7e-45 153.8 0.0 5.6e-45 153.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFQ99129.1 - 4.2e-23 82.4 0.0 3.6e-20 72.7 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase RabGAP-TBC PF00566.18 KFQ99130.1 - 4.3e-43 147.5 6.0 9.7e-43 146.3 6.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.22 KFQ99132.1 - 9.4e-52 172.7 0.0 6.4e-18 64.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 KFQ99132.1 - 2.1e-10 40.5 0.0 0.089 12.8 0.0 4.0 3 1 0 3 3 3 3 RNA binding domain RRM_7 PF16367.5 KFQ99132.1 - 6e-05 23.1 0.1 0.35 11.0 0.0 3.5 3 1 0 3 3 3 2 RNA recognition motif PHM7_cyt PF14703.6 KFQ99132.1 - 0.00087 19.6 3.0 0.71 10.1 0.1 4.2 3 1 1 4 4 4 2 Cytosolic domain of 10TM putative phosphate transporter Syndecan PF01034.20 KFQ99148.1 - 2.6e-27 94.5 0.0 3.8e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.18 KFQ99148.1 - 0.057 13.7 1.1 0.17 12.1 0.0 2.2 2 1 1 3 3 3 0 Glycophorin A TssR PF17643.1 KFQ99148.1 - 0.28 9.1 0.1 0.34 8.8 0.1 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssR PUF PF00806.19 KFQ99149.1 - 3e-74 240.7 8.7 1.1e-09 37.5 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 KFQ99149.1 - 0.021 15.2 1.2 5.6 7.3 0.1 3.9 1 1 3 4 4 4 0 CPL (NUC119) domain sCache_2 PF17200.4 KFQ99149.1 - 0.029 14.2 0.2 52 3.6 0.0 4.1 4 0 0 4 4 4 0 Single Cache domain 2 Mt_ATP-synt_B PF05405.14 KFQ99149.1 - 3.9 7.1 6.0 9.6 5.8 0.2 3.3 3 1 0 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) AA_permease_2 PF13520.6 KFQ99150.1 - 2.1e-56 191.6 45.4 2.7e-56 191.2 45.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFQ99150.1 - 4.1e-24 85.0 43.1 6.6e-24 84.3 43.1 1.3 1 1 0 1 1 1 1 Amino acid permease HRG PF16954.5 KFQ99150.1 - 0.34 11.3 6.5 0.38 11.2 0.3 4.1 2 1 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene DUF4448 PF14610.6 KFQ99150.1 - 0.56 9.9 1.7 8 6.2 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Ras PF00071.22 KFQ99151.1 - 1.4e-37 128.8 0.0 1.6e-37 128.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ99151.1 - 2.9e-17 63.0 0.0 4.1e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ99151.1 - 2.2e-09 37.0 0.0 3.3e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFQ99151.1 - 0.00097 18.6 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KFQ99151.1 - 0.0071 16.1 0.1 0.18 11.6 0.1 2.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 KFQ99152.1 - 1.1e-57 194.2 0.0 1.3e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ99152.1 - 4.8e-23 81.7 0.0 7.4e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ99152.1 - 6.5e-11 42.0 0.0 1.2e-10 41.1 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFQ99152.1 - 0.00011 21.8 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFQ99152.1 - 0.021 14.7 0.0 0.09 12.7 0.0 2.0 2 1 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 KFQ99152.1 - 0.03 13.7 0.0 0.046 13.1 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFQ99152.1 - 0.05 13.0 0.0 0.077 12.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PX PF00787.24 KFQ99154.1 - 8.7e-12 45.0 0.9 2e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 PX domain Ribosomal_60s PF00428.19 KFQ99154.1 - 9.6 6.9 17.3 2.9 8.5 5.5 3.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein TGF_beta PF00019.20 KFQ99155.1 - 6.5e-34 117.0 0.5 9.6e-34 116.5 0.5 1.2 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFQ99155.1 - 5e-13 49.4 0.0 6.8e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 TGF-beta propeptide LIDHydrolase PF10230.9 KFQ99156.1 - 6.7e-86 288.1 0.0 7.9e-86 287.9 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 KFQ99156.1 - 0.00086 19.2 0.0 0.005 16.7 0.0 2.0 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_6 PF12697.7 KFQ99156.1 - 0.0015 19.1 0.0 0.0017 19.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFQ99156.1 - 0.0053 16.0 0.0 0.0086 15.4 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KFQ99156.1 - 0.024 13.5 0.1 0.074 12.0 0.0 1.9 2 1 1 3 3 3 0 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 KFQ99156.1 - 0.062 12.9 0.0 0.14 11.8 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF900 PF05990.12 KFQ99156.1 - 0.065 12.7 0.1 0.14 11.6 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) BH4 PF02180.17 KFQ99159.1 - 5.2 7.0 11.7 52 3.8 0.2 4.2 1 1 4 5 5 5 0 Bcl-2 homology region 4 RVT_1 PF00078.27 KFQ99160.1 - 0.0014 18.2 0.1 0.0031 17.1 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rnk_N PF14760.6 KFQ99163.1 - 0.09 13.3 1.3 7.2 7.2 1.3 2.5 1 1 0 1 1 1 0 Rnk N-terminus DUF2868 PF11067.8 KFQ99163.1 - 0.23 11.0 0.7 0.35 10.3 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) AAA PF00004.29 KFQ99165.1 - 1.8e-47 161.1 0.0 1.2e-40 139.0 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 KFQ99165.1 - 2.5e-17 62.7 0.1 6.4e-17 61.4 0.1 1.7 1 0 0 1 1 1 1 Bromodomain AAA_lid_3 PF17862.1 KFQ99165.1 - 3.5e-12 45.9 0.0 1.1e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KFQ99165.1 - 4.1e-08 33.8 0.1 0.00033 21.1 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain IstB_IS21 PF01695.17 KFQ99165.1 - 7e-06 25.9 0.0 3.9e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 KFQ99165.1 - 8.8e-05 22.7 0.0 0.00029 21.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFQ99165.1 - 0.00061 20.1 0.1 0.05 13.9 0.1 3.6 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFQ99165.1 - 0.0051 16.8 0.1 0.059 13.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KFQ99165.1 - 0.0055 16.2 0.0 0.25 10.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF1088 PF06469.11 KFQ99165.1 - 0.011 15.4 1.4 0.026 14.2 1.4 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) RNA_helicase PF00910.22 KFQ99165.1 - 0.013 15.8 0.0 0.058 13.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase DUF2075 PF09848.9 KFQ99165.1 - 0.015 14.5 0.0 0.032 13.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 KFQ99165.1 - 0.015 15.4 0.0 1.4 9.0 0.0 2.8 2 1 1 3 3 3 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 KFQ99165.1 - 0.015 14.7 0.0 0.23 10.8 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ResIII PF04851.15 KFQ99165.1 - 0.022 14.8 0.0 0.13 12.3 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RuvB_N PF05496.12 KFQ99165.1 - 0.028 14.2 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KFQ99165.1 - 0.028 15.0 2.6 0.076 13.6 0.0 2.7 2 1 0 2 2 1 0 AAA domain TIP49 PF06068.13 KFQ99165.1 - 0.046 12.9 0.0 0.2 10.8 0.0 1.9 2 0 0 2 2 2 0 TIP49 P-loop domain Sigma54_activat PF00158.26 KFQ99165.1 - 0.068 12.9 0.0 0.76 9.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 KFQ99165.1 - 0.11 12.4 0.0 0.65 9.9 0.1 2.3 2 1 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 KFQ99165.1 - 0.14 11.8 0.0 0.34 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFQ99165.1 - 0.19 11.4 0.0 0.91 9.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KFQ99165.1 - 0.41 10.4 0.0 0.41 10.4 0.0 3.2 4 1 0 4 4 2 0 AAA domain DUF4746 PF15928.5 KFQ99165.1 - 0.77 9.1 4.7 1.4 8.2 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4636 PF15468.6 KFQ99165.1 - 1.9 8.1 6.0 0.55 9.9 1.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4636) SEP PF08059.13 KFQ99166.1 - 5.9e-26 90.8 0.7 1.4e-25 89.7 0.2 1.8 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 KFQ99166.1 - 3.6e-15 55.9 0.1 1.1e-14 54.4 0.1 1.9 2 0 0 2 2 2 1 UBX domain DNA_mis_repair PF01119.19 KFQ99166.1 - 0.09 12.5 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 DNA mismatch repair protein, C-terminal domain MFS_2 PF13347.6 KFQ99167.1 - 6.6e-96 321.5 20.0 1.2e-94 317.3 20.0 1.9 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 KFQ99167.1 - 5e-09 35.5 29.5 6.4e-08 31.9 8.9 2.9 2 1 0 3 3 3 2 Major Facilitator Superfamily ATP-synt_8 PF00895.20 KFQ99167.1 - 3.1 8.3 6.6 1.8 9.1 0.1 3.4 3 0 0 3 3 3 0 ATP synthase protein 8 WDCP PF15390.6 KFQ99168.1 - 0 1046.9 0.0 0 1046.7 0.0 1.0 1 0 0 1 1 1 1 WD repeat and coiled-coil-containing protein family WDCP PF15390.6 KFQ99169.1 - 0 1105.1 0.0 0 1105.0 0.0 1.0 1 0 0 1 1 1 1 WD repeat and coiled-coil-containing protein family ANAPC4_WD40 PF12894.7 KFQ99169.1 - 0.0042 17.3 0.9 0.021 15.1 0.1 2.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain FKBP_C PF00254.28 KFQ99171.1 - 1.1e-28 99.3 0.0 1.3e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RRM_1 PF00076.22 KFQ99172.1 - 1.5e-16 60.0 0.3 1.2e-15 57.0 0.0 2.2 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFQ99172.1 - 0.00021 20.9 0.0 0.00026 20.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ADH_zinc_N PF00107.26 KFQ99173.1 - 1.7e-21 76.6 0.1 3.2e-21 75.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFQ99173.1 - 3.6e-19 70.1 0.0 9.8e-19 68.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFQ99173.1 - 7.4e-09 35.5 0.1 7.4e-07 29.0 0.0 2.6 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain Profilin PF00235.19 KFQ99174.1 - 2.5e-25 89.2 0.0 2.8e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 Profilin RhoGEF PF00621.20 KFQ99175.1 - 0.0041 17.4 0.4 0.0054 17.0 0.4 1.3 1 0 0 1 1 1 1 RhoGEF domain DOT1 PF08123.13 KFQ99175.1 - 0.011 15.3 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 PH_13 PF16652.5 KFQ99176.1 - 2.6e-71 238.5 0.9 2.6e-71 238.5 0.9 3.6 3 1 1 4 4 3 1 Pleckstrin homology domain SH3_9 PF14604.6 KFQ99176.1 - 7.5e-66 217.8 2.4 1.6e-15 56.7 0.0 5.4 5 0 0 5 5 5 5 Variant SH3 domain SH3_1 PF00018.28 KFQ99176.1 - 9.5e-65 214.0 8.5 2.3e-15 55.9 0.1 5.5 5 0 0 5 5 5 5 SH3 domain SH3_2 PF07653.17 KFQ99176.1 - 1.7e-57 190.9 0.2 2.3e-13 49.6 0.1 5.5 5 0 0 5 5 5 5 Variant SH3 domain RhoGEF PF00621.20 KFQ99176.1 - 2.3e-43 148.6 0.1 2.3e-43 148.6 0.1 3.4 2 1 0 2 2 1 1 RhoGEF domain EF-hand_4 PF12763.7 KFQ99176.1 - 1.2e-29 102.3 0.0 2.1e-13 50.1 0.0 2.9 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand C2 PF00168.30 KFQ99176.1 - 4.5e-23 81.5 0.0 1.5e-22 79.8 0.0 1.9 1 0 0 1 1 1 1 C2 domain EF-hand_1 PF00036.32 KFQ99176.1 - 8.7e-10 37.5 0.2 0.0029 17.0 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFQ99176.1 - 7e-08 31.8 0.5 0.62 10.1 0.0 4.2 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 KFQ99176.1 - 1.7e-07 31.6 0.4 0.00058 20.3 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair PH PF00169.29 KFQ99176.1 - 0.00061 20.3 0.1 0.0023 18.4 0.1 2.0 1 0 0 1 1 1 1 PH domain INTAP PF16617.5 KFQ99176.1 - 0.018 15.4 1.2 0.018 15.4 1.2 2.7 2 0 0 2 2 2 0 Intersectin and clathrin adaptor AP2 binding region EF-hand_8 PF13833.6 KFQ99176.1 - 0.025 14.4 0.0 1.7 8.5 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 KFQ99176.1 - 0.029 13.9 0.9 8.7 6.0 0.1 3.3 3 0 0 3 3 3 0 EF hand DUF3800 PF12686.7 KFQ99176.1 - 0.22 12.2 0.9 2.4e+02 2.3 0.0 3.1 2 1 0 3 3 2 0 Protein of unknown function (DUF3800) CDC45 PF02724.14 KFQ99177.1 - 8.1 4.6 9.5 9.4 4.4 9.5 1.1 1 0 0 1 1 1 0 CDC45-like protein GCFC PF07842.12 KFQ99178.1 - 9.6e-28 97.6 3.3 6.6e-27 94.8 3.3 2.2 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein DUF3677 PF12432.8 KFQ99178.1 - 0.039 14.3 0.2 0.13 12.6 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3677) JIP_LZII PF16471.5 KFQ99178.1 - 6.3 7.0 13.0 0.31 11.3 2.6 3.6 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II Ribosomal_L19 PF01245.20 KFQ99179.1 - 2.4e-16 59.7 0.0 4.1e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 DUF4108 PF13390.6 KFQ99179.1 - 0.04 13.8 0.8 1.9 8.4 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4108) FAM176 PF14851.6 KFQ99180.1 - 4.6e-64 214.5 0.2 5.2e-64 214.3 0.2 1.0 1 0 0 1 1 1 1 FAM176 family VirB3 PF05101.13 KFQ99180.1 - 0.005 17.0 0.0 0.0079 16.4 0.0 1.3 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein DUF4576 PF15144.6 KFQ99180.1 - 0.043 13.7 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) DUF555 PF04475.12 KFQ99180.1 - 0.09 13.1 0.4 1.4 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF555) DUF755 PF05501.11 KFQ99180.1 - 1.8 8.8 7.5 2.7 8.3 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Patched PF02460.18 KFQ99182.1 - 2.3e-96 323.7 14.4 3.1e-96 323.3 14.4 1.1 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 KFQ99182.1 - 1.2e-19 70.7 3.0 1.2e-19 70.7 3.0 2.5 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Phage_holin_3_6 PF07332.11 KFQ99182.1 - 3.1 7.9 8.0 13 5.9 0.0 3.2 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III SH3_9 PF14604.6 KFQ99184.1 - 4.6e-45 151.3 4.8 1.3e-15 57.0 0.1 3.7 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 KFQ99184.1 - 1.9e-38 129.8 9.3 1.2e-12 47.2 0.1 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 KFQ99184.1 - 2.4e-35 120.0 7.4 1.8e-12 46.7 0.1 3.6 4 0 0 4 4 4 3 Variant SH3 domain XFP PF03894.15 KFQ99184.1 - 0.00039 20.2 0.0 1.2 8.8 0.0 3.1 3 0 0 3 3 3 2 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Filament PF00038.21 KFQ99184.1 - 0.0084 15.7 2.0 0.014 15.0 2.0 1.2 1 0 0 1 1 1 1 Intermediate filament protein betaPIX_CC PF16523.5 KFQ99184.1 - 2.5 8.0 7.6 7.6 6.4 7.6 1.8 1 1 0 1 1 1 0 betaPIX coiled coil 7tm_2 PF00002.24 KFQ99185.1 - 8.2e-33 113.7 21.7 1.5e-32 112.9 21.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Ig_3 PF13927.6 KFQ99185.1 - 2.7e-15 56.7 13.4 2.4e-10 40.9 0.1 3.7 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFQ99185.1 - 3.2e-15 56.1 16.7 2.8e-08 33.8 0.1 3.9 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFQ99185.1 - 3.6e-15 55.8 4.1 5.7e-10 39.1 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin I-set domain GPS PF01825.21 KFQ99185.1 - 1.9e-14 53.9 3.4 1.9e-14 53.9 3.4 2.7 2 0 0 2 2 1 1 GPCR proteolysis site, GPS, motif GAIN PF16489.5 KFQ99185.1 - 1.1e-09 38.1 3.2 3.1e-09 36.6 3.2 1.8 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Ig_2 PF13895.6 KFQ99185.1 - 2e-09 37.7 20.0 2.3e-07 31.1 0.2 4.5 4 1 0 4 4 4 2 Immunoglobulin domain SEA PF01390.20 KFQ99185.1 - 2.2e-08 34.1 0.9 5.5e-07 29.6 0.0 3.5 3 1 0 3 3 3 1 SEA domain Ig_5 PF16681.5 KFQ99185.1 - 6e-05 23.4 2.7 0.0037 17.6 0.0 3.3 2 1 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set PF07686.17 KFQ99185.1 - 7.9e-05 22.8 12.8 0.0014 18.7 0.3 5.5 4 2 0 4 4 4 1 Immunoglobulin V-set domain Izumo-Ig PF16706.5 KFQ99185.1 - 0.00047 20.2 0.4 0.068 13.2 0.0 3.3 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFQ99185.1 - 0.0088 15.6 2.6 0.64 9.6 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin domain Spp-24 PF07448.11 KFQ99185.1 - 0.067 13.4 3.0 0.15 12.2 0.8 2.7 2 0 0 2 2 2 0 Secreted phosphoprotein 24 (Spp-24) cystatin-like domain Astacin PF01400.24 KFQ99186.1 - 7.2e-68 228.0 0.0 1.1e-67 227.3 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MAM PF00629.23 KFQ99186.1 - 2.7e-38 131.4 0.1 4e-38 130.8 0.1 1.3 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu EGF PF00008.27 KFQ99186.1 - 1.2e-08 35.0 4.8 3.7e-08 33.5 4.8 1.9 1 0 0 1 1 1 1 EGF-like domain EGF_CA PF07645.15 KFQ99186.1 - 0.052 13.7 6.1 0.14 12.4 6.1 1.7 1 0 0 1 1 1 0 Calcium-binding EGF domain EGF_3 PF12947.7 KFQ99186.1 - 1.4 9.2 6.0 4.1 7.7 6.0 1.9 1 0 0 1 1 1 0 EGF domain hEGF PF12661.7 KFQ99186.1 - 1.8 9.3 8.7 0.58 10.9 5.3 2.1 2 0 0 2 2 2 0 Human growth factor-like EGF TAS2R PF05296.13 KFQ99187.1 - 4.7e-63 213.1 37.2 5.4e-63 212.9 37.2 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) Ank_4 PF13637.6 KFQ99188.1 - 2.4e-20 72.6 0.5 6.2e-10 39.4 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFQ99188.1 - 3e-16 59.8 0.0 8.9e-15 55.1 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFQ99188.1 - 9.5e-14 50.2 0.1 0.00024 21.3 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KFQ99188.1 - 1.8e-11 44.1 0.4 0.00027 21.2 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFQ99188.1 - 4.5e-09 36.4 1.2 0.00026 21.3 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat PAF-AH_p_II PF03403.13 KFQ99189.1 - 2.9e-178 592.1 0.0 3.6e-178 591.9 0.0 1.0 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KFQ99189.1 - 1.1e-08 34.3 0.0 3.9e-08 32.5 0.0 1.8 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KFQ99189.1 - 9.8e-06 25.0 0.0 0.065 12.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KFQ99189.1 - 3.9e-05 22.8 0.0 0.038 13.0 0.0 2.3 2 0 0 2 2 2 2 Chlorophyllase Peptidase_S9 PF00326.21 KFQ99189.1 - 6.4e-05 22.5 0.0 0.0002 20.9 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 KFQ99189.1 - 0.0038 17.0 0.0 0.014 15.2 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 KFQ99189.1 - 0.0044 16.6 0.0 0.011 15.3 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KFQ99189.1 - 0.044 13.6 0.0 0.12 12.2 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.12 KFQ99189.1 - 0.061 12.0 0.0 0.69 8.5 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.25 KFQ99189.1 - 0.085 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) BAAT_C PF08840.11 KFQ99189.1 - 0.11 12.4 0.0 0.49 10.3 0.0 2.0 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 KFQ99189.1 - 0.11 12.3 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KFQ99189.1 - 0.14 12.8 0.0 0.31 11.6 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family Tcp10_C PF07202.13 KFQ99190.1 - 0.21 11.5 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 T-complex protein 10 C-terminus TUDOR PF00567.24 KFQ99191.1 - 2e-155 508.9 5.5 1.7e-32 112.0 0.3 7.5 7 0 0 7 7 7 7 Tudor domain Agenet PF05641.12 KFQ99191.1 - 4.9e-11 42.9 6.9 0.11 12.9 0.0 7.9 8 0 0 8 8 8 3 Agenet domain SMN PF06003.12 KFQ99191.1 - 7.7e-11 41.7 0.6 0.0069 15.7 0.1 4.6 4 0 0 4 4 4 2 Survival motor neuron protein (SMN) DUF4537 PF15057.6 KFQ99191.1 - 1.4e-09 38.0 1.4 0.13 12.3 0.0 6.6 6 1 0 6 6 6 2 Domain of unknown function (DUF4537) DUF1325 PF07039.11 KFQ99191.1 - 1.9e-06 28.0 0.0 1.2 9.2 0.0 4.3 5 0 0 5 5 5 2 SGF29 tudor-like domain Tudor_FRX1 PF18336.1 KFQ99191.1 - 0.001 18.9 0.1 0.26 11.2 0.0 3.5 4 0 0 4 4 4 1 Fragile X mental retardation Tudor domain Spore_coat_CotO PF14153.6 KFQ99191.1 - 0.018 15.0 0.2 29 4.5 0.0 5.0 5 0 0 5 5 5 0 Spore coat protein CotO Tudor_2 PF18104.1 KFQ99191.1 - 0.31 10.8 5.7 7 6.4 0.1 4.4 4 0 0 4 4 4 0 Jumonji domain-containing protein 2A Tudor domain Mito_carr PF00153.27 KFQ99192.1 - 2.6e-67 222.8 0.8 5.4e-21 74.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein p450 PF00067.22 KFQ99193.1 - 4.1e-58 197.3 0.1 6.3e-58 196.6 0.1 1.3 1 0 0 1 1 1 1 Cytochrome P450 Calcipressin PF04847.12 KFQ99194.1 - 4.2e-64 215.7 0.3 5.3e-64 215.4 0.3 1.1 1 0 0 1 1 1 1 Calcipressin RRM_1 PF00076.22 KFQ99194.1 - 0.012 15.4 0.3 0.023 14.5 0.3 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFQ99194.1 - 0.035 13.9 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Phosphodiest PF01663.22 KFQ99195.1 - 5e-84 282.9 2.3 5.8e-84 282.7 2.3 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KFQ99195.1 - 2.5e-05 23.8 0.0 0.19 11.1 0.0 2.6 2 1 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 KFQ99195.1 - 0.13 11.6 0.0 0.3 10.4 0.0 1.5 1 1 0 1 1 1 0 Metalloenzyme superfamily Phosphodiest PF01663.22 KFQ99196.1 - 4.9e-84 282.9 0.9 5.8e-84 282.7 0.9 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KFQ99196.1 - 1.2e-07 31.4 0.0 0.00013 21.4 0.0 2.3 1 1 1 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 KFQ99196.1 - 0.00011 21.7 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF1501 PF07394.12 KFQ99196.1 - 0.078 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) PglZ PF08665.12 KFQ99196.1 - 0.081 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 PglZ domain GST_C_2 PF13410.6 KFQ99198.1 - 9e-09 35.2 0.0 2.4e-08 33.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFQ99198.1 - 2.7e-06 27.7 0.0 4.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFQ99198.1 - 9.8e-06 25.8 0.0 1.7e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFQ99198.1 - 0.00022 21.4 0.8 0.0012 19.1 0.3 2.5 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFQ99198.1 - 0.021 15.0 0.8 0.051 13.8 0.3 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain TFIID-18kDa PF02269.16 KFQ99200.1 - 1.6e-29 101.8 0.1 5.4e-29 100.1 0.3 1.9 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Hit1_C PF18268.1 KFQ99200.1 - 0.041 14.0 0.3 0.1 12.8 0.3 1.6 1 0 0 1 1 1 0 Hit1 C-terminal DUF2849 PF11011.8 KFQ99200.1 - 0.096 13.4 0.1 0.29 11.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2849) Myb_Cef PF11831.8 KFQ99201.1 - 6.9e-86 287.7 5.0 6.9e-86 287.7 5.0 3.8 5 0 0 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KFQ99201.1 - 7.2e-18 64.5 5.4 4.1e-09 36.5 1.2 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFQ99201.1 - 4.4e-17 62.1 7.3 8.1e-12 45.2 3.5 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain Pox_A_type_inc PF04508.12 KFQ99201.1 - 5.1 7.1 8.4 1.4 8.9 2.2 3.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat 7tm_1 PF00001.21 KFQ99204.1 - 2e-35 122.4 13.8 2.4e-35 122.1 13.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFQ99204.1 - 1.9e-06 27.5 11.8 3.1e-06 26.7 11.8 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.9 KFQ99204.1 - 0.00026 20.4 14.7 0.0062 15.9 14.7 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 KFQ99204.1 - 0.06 13.1 7.1 0.12 12.0 7.1 1.6 1 1 0 1 1 1 0 Olfactory receptor Bac_rhodopsin PF01036.18 KFQ99204.1 - 0.56 9.7 10.3 0.061 12.9 5.0 2.0 2 1 0 2 2 2 0 Bacteriorhodopsin-like protein Ni_hydr_CYTB PF01292.20 KFQ99204.1 - 1.7 8.2 8.8 0.69 9.5 5.6 1.9 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 MM_CoA_mutase PF01642.22 KFQ99206.1 - 1.4e-236 786.0 0.0 1.7e-236 785.8 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 KFQ99206.1 - 6.5e-15 55.2 0.1 1.9e-14 53.7 0.1 1.9 1 0 0 1 1 1 1 B12 binding domain PMBR PF09373.10 KFQ99206.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 Pseudomurein-binding repeat CENP-Q PF13094.6 KFQ99207.1 - 2.4e-18 66.9 14.6 4e-18 66.2 14.6 1.4 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF812 PF05667.11 KFQ99207.1 - 0.0003 19.8 11.8 0.00036 19.6 11.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) ATG16 PF08614.11 KFQ99207.1 - 0.00041 20.6 6.1 0.00078 19.7 6.1 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4011 PF13195.6 KFQ99207.1 - 0.0025 17.8 2.9 0.0025 17.8 2.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4011) Spc7 PF08317.11 KFQ99207.1 - 0.031 13.2 12.7 0.062 12.2 12.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein SMBP PF16785.5 KFQ99207.1 - 0.037 14.3 1.3 0.064 13.5 1.3 1.3 1 0 0 1 1 1 0 Small metal-binding protein LRRFIP PF09738.9 KFQ99207.1 - 0.04 13.4 13.5 0.038 13.5 12.6 1.5 1 1 0 1 1 1 0 LRRFIP family Interfer-bind PF09294.10 KFQ99207.1 - 0.15 12.4 2.6 0.24 11.8 0.5 2.1 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III Exonuc_VII_L PF02601.15 KFQ99207.1 - 0.4 10.2 8.5 0.49 9.9 8.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prominin PF05478.11 KFQ99207.1 - 0.41 8.5 9.6 0.62 7.9 9.6 1.2 1 0 0 1 1 1 0 Prominin FUSC PF04632.12 KFQ99207.1 - 0.61 8.5 1.0 0.71 8.3 1.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family V_ATPase_I PF01496.19 KFQ99207.1 - 0.74 7.7 7.0 0.85 7.5 7.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4140 PF13600.6 KFQ99207.1 - 0.75 10.3 7.0 0.28 11.6 3.6 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) ERM PF00769.19 KFQ99207.1 - 0.84 9.4 17.3 0.15 11.8 12.7 1.9 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Nup88 PF10168.9 KFQ99207.1 - 1.8 6.3 15.5 0.2 9.4 11.3 1.4 2 0 0 2 2 2 0 Nuclear pore component THOC7 PF05615.13 KFQ99207.1 - 3.8 7.8 14.8 0.76 10.1 10.8 2.0 2 1 0 2 2 2 0 Tho complex subunit 7 LMBR1 PF04791.16 KFQ99207.1 - 3.9 6.3 4.9 4.6 6.0 4.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1664 PF07889.12 KFQ99207.1 - 9.2 6.3 10.9 1.2 9.2 6.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Nsp1_C PF05064.13 KFQ99207.1 - 9.8 6.0 17.8 0.47 10.3 8.1 2.6 3 0 0 3 3 3 0 Nsp1-like C-terminal region p450 PF00067.22 KFQ99208.1 - 1.1e-132 443.1 0.0 1.3e-132 442.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Bac_RepA_C PF18008.1 KFQ99208.1 - 0.067 13.6 0.1 0.22 11.9 0.0 1.8 2 0 0 2 2 2 0 Replication initiator protein A C-terminal domain p450 PF00067.22 KFQ99209.1 - 1.2e-137 459.5 0.0 1.4e-137 459.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ammonium_transp PF00909.21 KFQ99210.1 - 4.3e-76 256.2 22.6 5.3e-76 255.9 22.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family TF_AP-2 PF03299.14 KFQ99211.1 - 4.3e-85 284.7 0.0 7.5e-85 283.9 0.0 1.4 1 0 0 1 1 1 1 Transcription factor AP-2 TF_AP-2 PF03299.14 KFQ99213.1 - 1.9e-87 292.3 0.0 2.6e-87 291.9 0.0 1.2 1 0 0 1 1 1 1 Transcription factor AP-2 TIG PF01833.24 KFQ99214.1 - 5.4e-62 205.9 48.4 2.5e-08 33.9 0.0 14.0 12 3 1 13 13 13 10 IPT/TIG domain G8 PF10162.9 KFQ99214.1 - 1.2e-48 164.3 0.0 7.5e-27 93.9 0.0 3.0 2 0 0 2 2 2 2 G8 domain Beta_helix PF13229.6 KFQ99214.1 - 2.5e-11 43.7 7.4 7.8e-05 22.6 0.0 4.4 2 1 1 3 3 3 2 Right handed beta helix region PA14 PF07691.12 KFQ99214.1 - 0.00027 20.7 0.0 0.00059 19.7 0.0 1.5 1 0 0 1 1 1 1 PA14 domain GLEYA PF10528.9 KFQ99214.1 - 0.00046 20.5 0.1 0.0044 17.4 0.0 2.6 2 0 0 2 2 2 1 GLEYA domain NosD PF05048.13 KFQ99214.1 - 0.018 14.3 6.3 1.2 8.3 0.4 3.5 2 2 0 3 3 3 0 Periplasmic copper-binding protein (NosD) IL17 PF06083.11 KFQ99215.1 - 1e-30 106.0 1.1 1.8e-30 105.2 1.1 1.4 1 0 0 1 1 1 1 Interleukin-17 IL17 PF06083.11 KFQ99216.1 - 8.7e-31 106.2 0.3 1.9e-30 105.2 0.1 1.6 2 0 0 2 2 2 1 Interleukin-17 MCM PF00493.23 KFQ99217.1 - 2.8e-96 320.9 0.0 4.7e-96 320.2 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFQ99217.1 - 3.9e-34 117.2 0.3 3.9e-34 117.2 0.3 1.6 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 KFQ99217.1 - 1.7e-21 76.5 3.3 4.7e-21 75.0 3.3 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFQ99217.1 - 4.8e-11 43.2 0.1 4.8e-11 43.2 0.1 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFQ99217.1 - 7.7e-07 28.7 0.0 4.7e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KFQ99217.1 - 0.0026 17.6 0.0 0.0078 16.1 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFQ99217.1 - 0.0075 16.3 0.0 0.021 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) HsbA PF12296.8 KFQ99217.1 - 0.058 13.8 0.5 0.56 10.6 0.0 2.6 3 0 0 3 3 3 0 Hydrophobic surface binding protein A Sigma54_activat PF00158.26 KFQ99217.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 KFQ99217.1 - 0.47 10.8 2.2 1.5 9.2 0.1 2.7 2 1 0 2 2 2 0 AAA ATPase domain HlyIII PF03006.20 KFQ99218.1 - 6.9e-51 173.1 17.4 1.1e-50 172.5 17.4 1.3 1 0 0 1 1 1 1 Haemolysin-III related DUF5504 PF17608.2 KFQ99218.1 - 0.0063 16.6 4.3 0.015 15.4 4.3 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5504) DUF1126 PF06565.12 KFQ99219.1 - 2.1e-104 342.5 2.7 1.2e-35 121.5 0.3 3.4 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_1 PF00036.32 KFQ99219.1 - 0.00025 20.4 0.0 0.02 14.4 0.0 3.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KFQ99219.1 - 0.00046 19.9 0.2 0.0098 15.8 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 KFQ99219.1 - 0.0035 17.8 0.1 0.021 15.3 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair DUF5580 PF17743.1 KFQ99219.1 - 0.022 13.3 0.1 0.029 12.9 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_8 PF13833.6 KFQ99219.1 - 0.16 11.8 0.3 0.64 9.9 0.0 2.1 3 0 0 3 3 3 0 EF-hand domain pair TRAM_LAG1_CLN8 PF03798.16 KFQ99220.1 - 7.5e-23 81.3 16.5 7.5e-23 81.3 16.5 1.4 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KFQ99220.1 - 5.3e-19 67.6 0.3 5.3e-19 67.6 0.3 2.3 2 0 0 2 2 2 1 TRAM1-like protein RhodobacterPufX PF11511.8 KFQ99220.1 - 0.044 13.4 0.0 0.15 11.7 0.0 1.9 1 0 0 1 1 1 0 Intrinsic membrane protein PufX DUF2207 PF09972.9 KFQ99220.1 - 1.5 7.5 4.2 0.37 9.5 1.2 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4834 PF16118.5 KFQ99220.1 - 3.6 8.6 7.3 14 6.7 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Defensin_beta PF00711.19 KFQ99223.1 - 3.3e-08 33.4 10.8 4.5e-08 33.0 10.8 1.2 1 0 0 1 1 1 1 Beta defensin Defensin_propep PF00879.18 KFQ99223.1 - 0.01 16.1 2.3 0.012 15.8 2.3 1.1 1 0 0 1 1 1 1 Defensin propeptide Defensin_beta PF00711.19 KFQ99224.1 - 4.3e-07 29.9 10.9 5.1e-07 29.6 10.9 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_propep PF00879.18 KFQ99224.1 - 0.041 14.1 0.1 0.046 14.0 0.1 1.1 1 0 0 1 1 1 0 Defensin propeptide Defensin_beta PF00711.19 KFQ99225.1 - 1.4e-07 31.4 13.3 1.7e-07 31.1 13.3 1.1 1 0 0 1 1 1 1 Beta defensin DEFB136 PF17333.2 KFQ99225.1 - 4.2e-05 23.4 8.0 5.6e-05 23.0 8.0 1.1 1 0 0 1 1 1 1 Beta defensin 136 Defensin_beta PF00711.19 KFQ99226.1 - 6.1e-07 29.4 10.3 7.4e-07 29.1 10.3 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_beta PF00711.19 KFQ99227.1 - 9.2e-13 48.0 6.7 1e-12 47.9 6.7 1.0 1 0 0 1 1 1 1 Beta defensin DUF4707 PF15806.5 KFQ99227.1 - 0.18 10.7 0.4 0.17 10.8 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4707) Defensin_beta PF00711.19 KFQ99228.1 - 7.2e-11 41.9 7.0 8.4e-11 41.7 7.0 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_propep PF00879.18 KFQ99228.1 - 0.022 15.0 0.0 0.027 14.7 0.0 1.2 1 0 0 1 1 1 0 Defensin propeptide Defensin_beta PF00711.19 KFQ99229.1 - 5.3e-07 29.6 24.1 3.9e-05 23.6 8.6 2.7 2 1 0 2 2 2 2 Beta defensin Inhibitor_I68 PF10468.9 KFQ99229.1 - 0.022 15.1 10.6 0.029 14.7 10.6 1.2 1 0 0 1 1 1 0 Carboxypeptidase inhibitor I68 Defensin_beta_2 PF13841.6 KFQ99230.1 - 0.00025 21.5 7.2 0.00032 21.1 7.2 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_beta PF00711.19 KFQ99230.1 - 0.00051 20.0 6.5 0.00063 19.7 6.5 1.1 1 0 0 1 1 1 1 Beta defensin m_DGTX_Dc1a_b_c PF17491.2 KFQ99230.1 - 0.18 12.5 3.5 0.24 12.1 3.5 1.3 1 1 0 1 1 1 0 Spider Toxins mu-diguetoxin-1 a, b and c Defensin_beta PF00711.19 KFQ99231.1 - 6.1e-11 42.2 12.5 7.1e-11 41.9 12.5 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_beta_2 PF13841.6 KFQ99231.1 - 0.068 13.7 13.2 0.099 13.1 13.2 1.3 1 0 0 1 1 1 0 Beta defensin Gamma-thionin PF00304.20 KFQ99231.1 - 0.073 13.4 10.2 0.088 13.1 10.2 1.1 1 0 0 1 1 1 0 Gamma-thionin family Peptidase_C1 PF00112.23 KFQ99233.1 - 1.1e-67 228.3 2.2 1.4e-67 228.0 2.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 KFQ99233.1 - 2.3e-19 69.0 0.5 5.1e-19 67.9 0.5 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 KFQ99233.1 - 0.08 11.7 1.8 3.7 6.2 0.3 2.1 2 0 0 2 2 2 0 Peptidase C1-like family SQS_PSY PF00494.19 KFQ99234.1 - 8.1e-36 123.9 0.0 1.1e-35 123.4 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase HAUS4 PF14735.6 KFQ99234.1 - 0.041 13.6 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 H2TH PF06831.14 KFQ99236.1 - 1.2e-11 44.4 0.0 2.3e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.24 KFQ99236.1 - 0.00012 22.6 0.0 0.00022 21.8 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain zf-FPG_IleRS PF06827.14 KFQ99236.1 - 0.023 14.5 0.1 0.052 13.4 0.1 1.7 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS GATA-N PF05349.12 KFQ99237.1 - 5e-73 245.2 27.3 6.8e-73 244.8 27.3 1.2 1 0 0 1 1 1 1 GATA-type transcription activator, N-terminal GATA PF00320.27 KFQ99237.1 - 9.2e-30 102.0 15.5 1.2e-15 56.8 4.4 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KFQ99237.1 - 1.8e-06 27.3 5.3 0.009 15.5 0.6 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.18 KFQ99237.1 - 0.011 15.8 2.2 0.25 11.4 0.2 2.2 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf OrfB_Zn_ribbon PF07282.11 KFQ99237.1 - 0.019 14.9 3.8 0.61 10.0 0.1 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 KFQ99237.1 - 0.059 13.5 4.7 0.95 9.6 0.2 2.7 2 1 1 3 3 3 0 Zinc ribbon domain eIF-5_eIF-2B PF01873.17 KFQ99237.1 - 0.062 13.2 3.7 4.9 7.1 0.9 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 DZR PF12773.7 KFQ99237.1 - 0.081 13.0 6.6 2.6 8.1 0.6 2.7 1 1 2 3 3 3 0 Double zinc ribbon DUF2387 PF09526.10 KFQ99237.1 - 0.12 12.5 4.2 7.9 6.7 0.1 3.2 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) Auto_anti-p27 PF06677.12 KFQ99237.1 - 0.18 12.0 5.6 0.87 9.8 0.5 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OTT_1508_deam PF14441.6 KFQ99237.1 - 0.2 11.7 0.9 21 5.2 0.0 2.4 2 0 0 2 2 2 0 OTT_1508-like deaminase Cytochrom_c3_2 PF14537.6 KFQ99237.1 - 0.33 11.5 0.2 0.33 11.5 0.2 2.3 2 1 0 2 2 2 0 Cytochrome c3 Prim_Zn_Ribbon PF08273.12 KFQ99237.1 - 0.37 11.1 7.9 0.18 12.1 1.4 2.5 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase zf-CHY PF05495.12 KFQ99237.1 - 0.43 11.1 2.5 19 5.8 0.3 2.2 2 0 0 2 2 2 0 CHY zinc finger Cytochrome_C554 PF13435.6 KFQ99237.1 - 0.62 11.0 2.9 32 5.5 1.7 2.5 2 0 0 2 2 2 0 Cytochrome c554 and c-prime Cytochrome_C7 PF14522.6 KFQ99237.1 - 3.6 7.7 5.9 13 5.8 5.9 2.0 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Vps36-NZF-N PF16988.5 KFQ99237.1 - 5.4 6.5 8.3 1.9 8.0 0.4 3.4 2 2 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Pkinase_Tyr PF07714.17 KFQ99238.1 - 2.5e-94 315.4 0.0 3.2e-94 315.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ99238.1 - 7.2e-47 160.0 0.0 1e-46 159.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFQ99238.1 - 1.3e-26 92.4 0.1 2.4e-26 91.6 0.1 1.4 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 KFQ99238.1 - 0.0012 18.6 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFQ99238.1 - 0.0019 17.8 0.1 0.0046 16.5 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFQ99238.1 - 0.0055 16.4 0.3 0.015 15.0 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Haspin_kinase PF12330.8 KFQ99238.1 - 0.0062 15.5 0.1 0.01 14.8 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFQ99238.1 - 0.1 11.9 0.1 0.24 10.7 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAM167 PF11652.8 KFQ99239.1 - 1.5e-38 131.2 2.3 3.5e-38 130.0 2.3 1.6 1 0 0 1 1 1 1 FAM167 LURAP PF14854.6 KFQ99239.1 - 0.0022 17.9 0.4 0.0044 17.0 0.4 1.5 1 0 0 1 1 1 1 Leucine rich adaptor protein DUF2388 PF09498.10 KFQ99239.1 - 0.011 15.6 0.8 0.025 14.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) OMS28_porin PF03532.13 KFQ99239.1 - 0.096 11.9 0.2 0.13 11.5 0.2 1.1 1 0 0 1 1 1 0 OMS28 porin FapA PF03961.13 KFQ99239.1 - 0.36 9.4 1.8 0.41 9.2 1.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4530 PF15039.6 KFQ99239.1 - 0.7 10.1 8.9 0.032 14.4 2.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4530) Epimerase PF01370.21 KFQ99240.1 - 2.9e-22 79.3 0.0 1.4e-21 77.1 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFQ99240.1 - 2.6e-15 56.6 0.0 2e-14 53.8 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KFQ99240.1 - 2e-07 30.4 0.0 3.4e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KFQ99240.1 - 8.3e-07 28.3 0.0 1.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KFQ99240.1 - 1.5e-06 27.6 0.2 1.1e-05 24.7 0.0 2.3 2 1 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 KFQ99240.1 - 0.00058 19.1 0.0 0.0059 15.8 0.0 2.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KFQ99240.1 - 0.063 13.2 0.1 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 KR domain Myotub-related PF06602.14 KFQ99241.1 - 3.9e-102 341.8 0.7 4.6e-102 341.6 0.7 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Hydrolase_6 PF13344.6 KFQ99241.1 - 0.024 14.8 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Meleagrin PF08189.11 KFQ99242.1 - 1.5e-20 72.6 14.8 1.8e-20 72.3 14.8 1.1 1 0 0 1 1 1 1 Meleagrin/Cygnin family zf-MYND PF01753.18 KFQ99242.1 - 0.0063 16.6 3.0 0.0063 16.6 3.0 1.7 1 1 1 2 2 2 1 MYND finger Meleagrin PF08189.11 KFQ99243.1 - 1.8e-20 72.3 14.4 2.2e-20 72.0 14.4 1.1 1 0 0 1 1 1 1 Meleagrin/Cygnin family XK-related PF09815.9 KFQ99245.1 - 8.4e-101 337.4 21.2 9.8e-101 337.2 21.2 1.0 1 0 0 1 1 1 1 XK-related protein ECF_trnsprt PF12822.7 KFQ99245.1 - 0.093 12.8 6.9 0.17 12.0 6.9 1.5 1 0 0 1 1 1 0 ECF transporter, substrate-specific component G-patch PF01585.23 KFQ99246.1 - 6.6e-16 57.9 3.6 1.4e-15 56.9 3.6 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFQ99246.1 - 7.9e-09 35.5 1.4 7.9e-09 35.5 1.4 2.5 3 0 0 3 3 3 1 G-patch domain YcgL PF05166.13 KFQ99246.1 - 0.12 12.7 0.0 2.1 8.7 0.1 2.3 2 0 0 2 2 2 0 YcgL domain Sox17_18_mid PF12067.8 KFQ99247.1 - 6.2e-22 77.4 5.0 6.2e-22 77.4 5.0 1.9 2 0 0 2 2 2 1 Sox 17/18 central domain HMG_box PF00505.19 KFQ99247.1 - 3.3e-08 33.8 0.1 5.4e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFQ99247.1 - 0.0035 17.9 0.1 0.0066 17.0 0.1 1.4 1 0 0 1 1 1 1 HMG-box domain DCX PF03607.17 KFQ99249.1 - 6.9e-32 109.4 0.0 2.8e-20 72.1 0.0 2.2 2 0 0 2 2 2 2 Doublecortin Trypsin PF00089.26 KFQ99251.1 - 9.4e-46 156.4 0.0 1e-45 156.2 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFQ99251.1 - 1.5e-06 28.5 0.1 3e-06 27.6 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) PMSR PF01625.21 KFQ99252.1 - 4e-43 147.2 0.4 4.5e-43 147.1 0.4 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF43 PF01861.16 KFQ99252.1 - 0.2 10.8 0.0 0.26 10.5 0.0 1.1 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Kinesin PF00225.23 KFQ99253.1 - 2e-112 375.4 0.1 4e-112 374.4 0.1 1.6 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 KFQ99253.1 - 4.9e-34 118.2 0.0 4.1e-33 115.2 0.0 2.4 1 1 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 KFQ99253.1 - 1.3e-24 87.4 19.0 2.7e-19 70.0 1.4 3.9 3 1 1 4 4 4 2 Kinesin-associated Microtub_bd PF16796.5 KFQ99253.1 - 2.1e-24 86.2 0.0 4.9e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding CAP_GLY PF01302.25 KFQ99253.1 - 1.2e-23 82.9 1.3 2.2e-23 82.0 1.3 1.5 1 0 0 1 1 1 1 CAP-Gly domain KIF1B PF12423.8 KFQ99253.1 - 4.6e-17 62.2 0.5 1.8e-16 60.3 0.5 2.2 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.26 KFQ99253.1 - 6.3e-08 32.9 0.1 3.9e-07 30.3 0.0 2.3 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KFQ99253.1 - 0.0002 21.6 0.0 0.00059 20.1 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain KMP11 PF03037.16 KFQ99253.1 - 0.16 12.8 6.0 0.032 15.0 1.1 2.5 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 FOXP-CC PF16159.5 KFQ99253.1 - 6 7.6 6.2 6.3 7.5 3.4 2.6 2 0 0 2 2 2 0 FOXP coiled-coil domain HNF-1_N PF04814.13 KFQ99254.1 - 1.2e-62 212.1 3.7 2.5e-62 211.0 3.7 1.6 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Homeodomain PF00046.29 KFQ99254.1 - 1.6e-10 40.7 1.4 7.8e-10 38.5 0.1 2.8 3 1 0 3 3 3 1 Homeodomain Homeobox_KN PF05920.11 KFQ99254.1 - 2.9e-05 23.9 0.6 0.0022 17.9 0.1 3.0 2 1 0 2 2 2 1 Homeobox KN domain HTH_37 PF13744.6 KFQ99254.1 - 0.00099 19.0 0.4 0.00099 19.0 0.4 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 KFQ99254.1 - 0.0029 17.6 0.2 0.046 13.7 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 KFQ99254.1 - 0.003 17.6 0.1 0.0066 16.5 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_24 PF13412.6 KFQ99254.1 - 0.013 15.1 0.2 0.057 13.0 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding AbiJ_NTD3 PF18860.1 KFQ99254.1 - 0.014 15.0 0.4 0.24 10.9 0.1 2.5 3 0 0 3 3 3 0 AbiJ N-terminal domain 3 HTH_31 PF13560.6 KFQ99254.1 - 0.017 15.4 1.9 0.074 13.4 0.1 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain DUF494 PF04361.13 KFQ99254.1 - 0.036 14.0 0.1 0.081 12.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF494) NOC3p PF07540.11 KFQ99254.1 - 0.079 13.4 0.1 0.31 11.5 0.1 2.0 1 1 1 2 2 2 0 Nucleolar complex-associated protein Pex14_N PF04695.13 KFQ99254.1 - 0.085 13.5 4.1 0.1 13.2 1.7 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CUT PF02376.15 KFQ99254.1 - 0.085 13.0 1.1 0.26 11.5 0.1 2.3 3 0 0 3 3 2 0 CUT domain YdaS_antitoxin PF15943.5 KFQ99254.1 - 0.1 12.5 1.1 0.88 9.5 0.1 2.3 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 KFQ99254.1 - 0.25 11.2 0.2 0.25 11.2 0.2 2.6 3 0 0 3 3 3 0 Homeodomain-like domain Lactamase_B_6 PF16661.5 KFQ99255.1 - 2.1e-16 59.9 0.4 2e-14 53.5 0.1 3.1 3 1 1 4 4 4 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 KFQ99255.1 - 1.4e-06 28.6 0.0 2.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain Beta_lactamase3 PF17030.5 KFQ99255.1 - 0.013 14.7 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Putative beta-lactamase-like family Glyco_transf_64 PF09258.10 KFQ99256.1 - 2.8e-101 337.9 0.1 4.3e-101 337.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 KFQ99256.1 - 2.4e-56 191.2 0.0 4.3e-56 190.3 0.0 1.4 1 0 0 1 1 1 1 Exostosin family ADIP PF11559.8 KFQ99256.1 - 0.016 15.3 7.2 0.028 14.5 7.2 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Jnk-SapK_ap_N PF09744.9 KFQ99256.1 - 0.022 15.0 2.8 0.044 14.0 2.8 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 KFQ99256.1 - 0.027 14.5 2.3 0.06 13.4 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF812 PF05667.11 KFQ99256.1 - 0.036 13.0 2.3 0.059 12.3 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Seryl_tRNA_N PF02403.22 KFQ99256.1 - 0.044 14.0 4.9 0.096 12.9 4.9 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain MscS_porin PF12795.7 KFQ99256.1 - 0.063 12.8 4.9 0.1 12.1 4.9 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain EzrA PF06160.12 KFQ99256.1 - 0.15 10.2 4.0 0.25 9.5 4.0 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TPR_MLP1_2 PF07926.12 KFQ99256.1 - 0.17 12.0 12.6 0.015 15.3 8.0 1.5 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.7 KFQ99256.1 - 0.17 12.0 5.0 0.35 11.0 5.0 1.4 1 0 0 1 1 1 0 Tropomyosin like THOC7 PF05615.13 KFQ99256.1 - 0.22 11.8 6.4 0.075 13.3 3.3 1.7 2 0 0 2 2 2 0 Tho complex subunit 7 TMPIT PF07851.13 KFQ99256.1 - 0.22 10.7 2.2 0.48 9.6 2.2 1.4 1 0 0 1 1 1 0 TMPIT-like protein Noelin-1 PF12308.8 KFQ99256.1 - 0.25 11.3 1.9 0.57 10.2 1.9 1.5 1 0 0 1 1 1 0 Neurogenesis glycoprotein BRE1 PF08647.11 KFQ99256.1 - 0.3 11.2 6.5 0.59 10.2 6.5 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase CAMSAP_CC1 PF17095.5 KFQ99256.1 - 0.34 10.8 1.6 0.66 9.9 1.6 1.4 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin DUF724 PF05266.14 KFQ99256.1 - 1.3 8.8 4.5 2.4 7.9 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Spc7 PF08317.11 KFQ99256.1 - 1.8 7.3 7.7 3.7 6.3 7.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Cortex-I_coil PF09304.10 KFQ99256.1 - 4 7.7 8.5 2.6 8.3 5.3 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil YlqD PF11068.8 KFQ99256.1 - 4.7 7.6 7.5 9.8 6.6 7.5 1.4 1 0 0 1 1 1 0 YlqD protein DUF3450 PF11932.8 KFQ99256.1 - 6.4 6.0 6.1 4.1 6.6 3.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Frizzled PF01534.17 KFQ99258.1 - 1.7e-121 405.2 17.5 2.2e-121 404.9 17.5 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 KFQ99258.1 - 1e-27 97.0 7.8 2e-27 96.0 7.8 1.5 1 0 0 1 1 1 1 Fz domain DUF898 PF05987.13 KFQ99258.1 - 0.027 13.5 0.2 0.027 13.5 0.2 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) F-box-like PF12937.7 KFQ99259.1 - 7.2e-09 35.4 5.6 1.3e-08 34.6 5.6 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFQ99259.1 - 1.1e-07 31.5 2.8 1.1e-07 31.5 2.8 1.7 2 0 0 2 2 2 1 F-box domain DUF4508 PF14969.6 KFQ99259.1 - 0.0004 20.6 0.8 0.00078 19.7 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4508) Radical_SAM_C PF16199.5 KFQ99260.1 - 1.2e-34 118.1 0.0 2.8e-34 117.0 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KFQ99260.1 - 6.7e-22 78.6 2.1 4.4e-21 76.0 0.1 3.0 4 0 0 4 4 4 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KFQ99260.1 - 4.3e-10 39.9 0.1 8.1e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFQ99260.1 - 4.7e-05 23.3 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFQ99260.1 - 0.14 12.2 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Pkinase PF00069.25 KFQ99261.1 - 2.4e-49 168.1 0.0 9.9e-49 166.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ99261.1 - 1.2e-34 119.8 0.4 1e-25 90.5 0.0 2.6 1 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KFQ99261.1 - 0.00031 20.8 0.0 0.011 15.6 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFQ99261.1 - 0.0019 17.6 0.0 0.0037 16.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 KFQ99261.1 - 0.023 14.8 0.0 0.04 14.1 0.0 1.3 1 0 0 1 1 1 0 ABC1 family RIO1 PF01163.22 KFQ99261.1 - 0.028 14.0 0.0 0.076 12.6 0.0 1.7 2 0 0 2 2 2 0 RIO1 family DUF3091 PF11291.8 KFQ99261.1 - 0.07 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3091) Pkinase_fungal PF17667.1 KFQ99261.1 - 0.076 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KFQ99261.1 - 0.086 12.1 0.0 0.35 10.1 0.0 2.1 2 1 0 2 2 2 0 Kinase-like YrbL-PhoP_reg PF10707.9 KFQ99261.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Opiods_neuropep PF01160.18 KFQ99262.1 - 0.015 15.4 0.9 0.015 15.4 0.9 1.7 2 0 0 2 2 2 0 Vertebrate endogenous opioids neuropeptide FOXP-CC PF16159.5 KFQ99263.1 - 0.003 18.1 0.0 0.0087 16.7 0.0 1.8 2 0 0 2 2 2 1 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KFQ99263.1 - 0.32 12.0 0.2 0.32 12.0 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger PAS_11 PF14598.6 KFQ99264.1 - 2.5e-37 127.4 0.0 3.4e-33 114.1 0.0 2.5 2 0 0 2 2 2 2 PAS domain NCOA_u2 PF16665.5 KFQ99264.1 - 1.9e-33 115.3 17.3 1.9e-33 115.3 17.3 5.6 6 0 0 6 6 3 1 Unstructured region on nuclear receptor coactivator protein DUF1518 PF07469.12 KFQ99264.1 - 1.9e-31 108.2 41.4 1e-19 70.6 20.1 7.6 7 1 1 8 8 6 2 Domain of unknown function (DUF1518) SRC-1 PF08832.10 KFQ99264.1 - 9.4e-23 81.1 4.2 9.7e-22 77.8 4.2 2.9 1 0 0 1 1 1 1 Steroid receptor coactivator Nuc_rec_co-act PF08815.10 KFQ99264.1 - 7.2e-21 73.8 2.1 7.2e-21 73.8 2.1 2.4 3 0 0 3 3 3 1 Nuclear receptor coactivator PAS PF00989.25 KFQ99264.1 - 4.8e-09 36.2 0.0 3e-08 33.6 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 KFQ99264.1 - 1.2e-07 31.9 0.0 0.00041 20.6 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KFQ99264.1 - 1.2e-06 28.7 0.0 2.2e-05 24.7 0.0 2.7 2 0 0 2 2 2 1 PAS domain DUF4927 PF16279.5 KFQ99264.1 - 3e-06 28.2 5.2 3e-06 28.2 5.2 3.1 3 0 0 3 3 2 1 Domain of unknown function (DUF4927) HLH PF00010.26 KFQ99264.1 - 5.4e-06 26.3 0.5 5.4e-06 26.3 0.5 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_4 PF08448.10 KFQ99264.1 - 0.013 15.7 0.0 0.037 14.3 0.0 1.8 1 0 0 1 1 1 0 PAS fold PAS_12 PF18095.1 KFQ99264.1 - 0.054 13.1 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain CXCL17 PF15211.6 KFQ99264.1 - 0.3 11.9 2.8 6.2 7.6 0.2 2.7 2 0 0 2 2 2 0 VEGF co-regulated chemokine 1 CENP-O PF09496.10 KFQ99265.1 - 4.2e-12 46.5 2.6 1.2e-11 45.0 0.1 2.1 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component Takusan PF04822.13 KFQ99265.1 - 0.0029 17.5 0.5 0.0075 16.1 0.3 1.7 2 0 0 2 2 2 1 Takusan Lipoprotein_6 PF01441.19 KFQ99265.1 - 0.076 13.0 0.3 0.12 12.4 0.3 1.2 1 0 0 1 1 1 0 Lipoprotein Csm1_N PF18504.1 KFQ99265.1 - 0.19 12.1 5.7 0.45 10.9 5.7 1.6 1 0 0 1 1 1 0 Csm1 N-terminal domain DivIC PF04977.15 KFQ99265.1 - 0.29 10.9 5.0 0.74 9.6 5.0 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF4140 PF13600.6 KFQ99265.1 - 0.42 11.1 4.0 0.95 9.9 4.0 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.6 KFQ99265.1 - 1.1 8.6 4.5 0.3 10.4 1.8 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Guanylate_cyc PF00211.20 KFQ99266.1 - 1.3e-97 324.8 0.0 1.8e-53 180.9 0.0 2.5 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 KFQ99266.1 - 5.5e-34 118.0 4.1 1.4e-33 116.7 4.1 1.6 1 0 0 1 1 1 1 Adenylyl cyclase N-terminal extracellular and transmembrane region HNOBA PF07701.14 KFQ99266.1 - 0.014 14.9 0.9 0.8 9.1 0.5 2.3 2 0 0 2 2 2 0 Heme NO binding associated fn3_4 PF16794.5 KFQ99266.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Fibronectin-III type domain Ras PF00071.22 KFQ99267.1 - 1.2e-36 125.8 0.0 1.5e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ99267.1 - 4.3e-19 68.9 0.0 4e-18 65.8 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DnaJ PF00226.31 KFQ99267.1 - 3.4e-12 46.3 0.0 6.3e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Arf PF00025.21 KFQ99267.1 - 4.7e-12 45.7 0.0 6e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFQ99267.1 - 0.00051 19.6 0.0 0.0011 18.5 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain NPP PF08384.10 KFQ99269.1 - 1.8e-23 82.3 1.2 2.9e-23 81.7 1.2 1.3 1 0 0 1 1 1 1 Pro-opiomelanocortin, N-terminal region ACTH_domain PF00976.18 KFQ99269.1 - 9.3e-23 79.7 25.5 6e-08 32.4 1.9 3.7 3 0 0 3 3 3 3 Corticotropin ACTH domain Op_neuropeptide PF08035.11 KFQ99269.1 - 1.6e-15 56.7 0.0 2.7e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Opioids neuropeptide CAP_N PF01213.19 KFQ99269.1 - 4.6e-06 26.3 1.4 8.5e-06 25.5 1.4 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal NeA_P2 PF12312.8 KFQ99269.1 - 0.012 15.1 0.1 0.018 14.5 0.1 1.1 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein VIR_N PF15912.5 KFQ99269.1 - 0.089 12.4 5.3 0.14 11.8 5.3 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal PRIMA1 PF16101.5 KFQ99269.1 - 0.7 9.9 5.5 1.8 8.6 5.5 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Fibrinogen_C PF00147.18 KFQ99270.1 - 2.1e-43 148.7 0.6 2.4e-43 148.5 0.6 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Stathmin PF00836.19 KFQ99271.1 - 2.5e-53 179.7 14.4 3e-53 179.4 14.4 1.1 1 0 0 1 1 1 1 Stathmin family Pex19 PF04614.12 KFQ99271.1 - 0.0077 16.0 3.4 0.0085 15.9 3.4 1.1 1 0 0 1 1 1 1 Pex19 protein family Atg14 PF10186.9 KFQ99271.1 - 0.17 10.9 11.4 0.21 10.6 11.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 KFQ99271.1 - 0.24 11.5 9.4 0.27 11.3 9.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CCDC84 PF14968.6 KFQ99271.1 - 0.39 10.3 6.9 3.2 7.3 3.3 2.2 2 0 0 2 2 2 0 Coiled coil protein 84 DUF4510 PF14971.6 KFQ99271.1 - 2.5 8.5 9.0 9.8 6.5 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4510) NYD-SP28_assoc PF14775.6 KFQ99272.1 - 1.8e-20 72.8 1.4 1.8e-20 72.8 1.4 4.8 3 2 2 5 5 5 1 Sperm tail C-terminal domain NYD-SP28 PF14772.6 KFQ99272.1 - 2.2e-15 56.6 13.9 2.2e-15 56.6 13.9 5.8 3 2 3 6 6 6 1 Sperm tail RebB PF11747.8 KFQ99272.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Killing trait Neur_chan_memb PF02932.16 KFQ99273.1 - 7.2e-89 297.9 16.2 1.3e-63 215.2 12.8 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFQ99273.1 - 5.9e-79 264.5 3.6 7.5e-79 264.2 3.6 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Glycoprotein PF03409.15 KFQ99273.1 - 0.068 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Transmembrane glycoprotein Abhydrolase_1 PF00561.20 KFQ99274.1 - 5e-39 134.5 0.0 6.8e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFQ99274.1 - 4e-15 57.0 0.1 8.3e-15 56.0 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFQ99274.1 - 1.9e-14 53.6 0.0 2.1e-13 50.1 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 HAD_2 PF13419.6 KFQ99274.1 - 5.7e-09 36.3 0.0 1.1e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFQ99274.1 - 2e-07 31.5 0.0 3.8e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFQ99274.1 - 0.00027 20.9 0.0 0.0006 19.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Ndr PF03096.14 KFQ99274.1 - 0.023 13.4 0.0 0.037 12.7 0.0 1.2 1 0 0 1 1 1 0 Ndr family Esterase PF00756.20 KFQ99274.1 - 0.18 11.4 0.0 0.39 10.3 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Chlorophyllase2 PF12740.7 KFQ99274.1 - 0.21 10.5 0.0 0.35 9.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme SRCR PF00530.18 KFQ99275.1 - 1.4e-32 112.2 2.3 2.8e-32 111.2 2.3 1.5 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Collagen PF01391.18 KFQ99275.1 - 6.1e-14 51.5 56.7 1e-08 34.8 25.0 2.5 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) SRCR_2 PF15494.6 KFQ99275.1 - 2.5e-05 24.7 2.2 2.7e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain OppC_N PF12911.7 KFQ99275.1 - 0.039 13.9 0.1 0.07 13.1 0.1 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DASH_Dad4 PF08650.10 KFQ99275.1 - 0.074 13.0 0.0 13 5.9 0.0 2.6 2 0 0 2 2 2 0 DASH complex subunit Dad4 Fib_alpha PF08702.10 KFQ99275.1 - 0.29 11.3 6.5 0.66 10.2 0.3 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Pkinase PF00069.25 KFQ99276.1 - 3.7e-40 138.0 0.0 5e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ99276.1 - 5.4e-34 117.7 0.0 6.7e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KFQ99276.1 - 0.0094 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KFQ99276.1 - 0.031 13.1 0.0 0.054 12.3 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Acetyltransf_13 PF13880.6 KFQ99277.1 - 6.8e-29 99.7 0.0 1.3e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 KFQ99277.1 - 9.4e-17 60.6 0.5 2.9e-16 59.0 0.5 1.9 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO NFACT-R_1 PF05670.13 KFQ99278.1 - 4.6e-43 146.3 0.0 4.9e-43 146.2 0.0 1.0 1 0 0 1 1 1 1 NFACT protein RNA binding domain YscJ_FliF PF01514.17 KFQ99278.1 - 0.11 12.2 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family DUF1664 PF07889.12 KFQ99279.1 - 0.00026 21.0 14.6 0.41 10.7 0.2 5.0 1 1 5 6 6 6 2 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 KFQ99279.1 - 0.0025 18.3 9.2 0.63 10.6 0.2 5.0 3 1 2 5 5 5 1 Nucleopolyhedrovirus P10 protein DUF2203 PF09969.9 KFQ99279.1 - 0.032 14.9 3.7 1.1 10.0 0.2 3.4 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF948 PF06103.11 KFQ99279.1 - 0.035 14.4 13.9 5 7.5 0.2 5.0 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF948) BORCS7 PF16088.5 KFQ99279.1 - 0.044 14.1 5.4 1.1 9.6 0.8 3.2 3 0 0 3 3 2 0 BLOC-1-related complex sub-unit 7 ADIP PF11559.8 KFQ99279.1 - 0.049 13.7 7.9 0.058 13.5 0.2 3.2 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding CotJB PF12652.7 KFQ99279.1 - 0.063 13.5 0.2 0.36 11.1 0.2 2.3 2 0 0 2 2 2 0 CotJB protein Chordopox_A33R PF05966.12 KFQ99279.1 - 0.069 12.4 1.2 0.13 11.6 1.2 1.3 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Lebercilin PF15619.6 KFQ99279.1 - 0.079 12.6 7.9 6.8 6.3 0.3 3.2 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease ABC_tran_CTD PF16326.5 KFQ99279.1 - 0.081 13.2 7.1 1.3 9.4 0.3 3.9 4 0 0 4 4 4 0 ABC transporter C-terminal domain Fez1 PF06818.15 KFQ99279.1 - 0.091 13.2 8.2 2.8 8.4 1.3 3.1 1 1 2 3 3 3 0 Fez1 WEMBL PF05701.11 KFQ99279.1 - 0.093 11.4 2.5 0.097 11.4 1.5 1.4 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Phage_GP20 PF06810.11 KFQ99279.1 - 0.098 12.5 0.5 17 5.2 0.0 2.8 2 1 1 3 3 3 0 Phage minor structural protein GP20 DUF2703 PF10865.8 KFQ99279.1 - 0.11 12.7 1.3 0.43 10.8 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) T3SSipB PF16535.5 KFQ99279.1 - 0.11 13.0 0.9 1.2 9.6 0.0 2.4 1 1 2 3 3 3 0 Type III cell invasion protein SipB MCPsignal PF00015.21 KFQ99279.1 - 0.12 12.2 6.2 0.51 10.1 0.3 3.0 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain LRRFIP PF09738.9 KFQ99279.1 - 0.95 8.9 7.1 2.3 7.6 7.1 1.7 1 1 0 1 1 1 0 LRRFIP family UPF0184 PF03670.13 KFQ99279.1 - 1.3 9.4 6.2 6.4 7.2 0.2 3.8 3 1 2 5 5 5 0 Uncharacterised protein family (UPF0184) ATG16 PF08614.11 KFQ99279.1 - 2 8.6 9.8 1.8 8.8 3.7 3.0 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Myosin_tail_1 PF01576.19 KFQ99279.1 - 2.4 5.9 8.5 0.3 8.8 0.7 2.3 2 1 0 2 2 2 0 Myosin tail CCDC-167 PF15188.6 KFQ99279.1 - 2.7 8.4 6.5 21 5.5 0.5 3.7 2 2 1 3 3 3 0 Coiled-coil domain-containing protein 167 FlaC_arch PF05377.11 KFQ99279.1 - 4 7.9 10.3 19 5.7 0.0 5.4 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) TolA_bind_tri PF16331.5 KFQ99279.1 - 4.7 7.4 19.0 1 9.5 1.7 3.8 3 0 0 3 3 3 0 TolA binding protein trimerisation Laminin_II PF06009.12 KFQ99279.1 - 6 6.9 11.7 12 5.9 0.4 4.2 1 1 1 4 4 4 0 Laminin Domain II Clusterin PF01093.17 KFQ99280.1 - 6.3e-120 401.1 1.8 3.6e-101 339.3 0.6 2.2 2 0 0 2 2 2 2 Clusterin RE_AlwI PF09491.10 KFQ99280.1 - 0.17 10.6 0.9 0.25 10.1 0.9 1.1 1 0 0 1 1 1 0 AlwI restriction endonuclease EamA PF00892.20 KFQ99282.1 - 2.4e-11 44.0 18.7 3.5e-09 36.9 3.3 2.4 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KFQ99282.1 - 1.1e-08 34.8 2.5 1.2e-06 28.1 0.2 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 KFQ99282.1 - 2.3e-08 33.6 0.0 3.4e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter SLC35F PF06027.12 KFQ99282.1 - 3.8e-07 29.9 1.5 9.1e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 Solute carrier family 35 CRT-like PF08627.10 KFQ99282.1 - 8.9e-07 28.2 3.2 2.6e-05 23.3 0.1 2.1 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like Bax1-I PF01027.20 KFQ99282.1 - 0.0004 20.3 1.9 0.0004 20.3 1.9 2.6 2 1 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 TMEM234 PF10639.9 KFQ99282.1 - 0.23 11.5 3.5 1.4 8.9 0.8 2.2 2 0 0 2 2 2 0 Putative transmembrane family 234 Ion_trans_2 PF07885.16 KFQ99283.1 - 7.1e-29 99.6 12.2 1.1e-19 70.2 7.9 2.4 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 KFQ99283.1 - 0.0043 16.3 6.4 0.0063 15.8 6.4 1.3 1 0 0 1 1 1 1 Ion transport protein DUF4872 PF16169.5 KFQ99283.1 - 0.028 14.2 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4872) Fil_haemagg_2 PF13332.6 KFQ99287.1 - 0.026 14.7 3.5 0.26 11.4 0.1 2.5 2 0 0 2 2 2 0 Hemagglutinin repeat DUF4047 PF13256.6 KFQ99287.1 - 0.35 11.1 6.8 2.9 8.1 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) AbiH PF14253.6 KFQ99287.1 - 6.9 6.5 9.2 0.37 10.6 0.5 2.7 2 1 0 2 2 2 0 Bacteriophage abortive infection AbiH SAM_2 PF07647.17 KFQ99288.1 - 2.7e-10 40.2 0.0 3.9e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFQ99288.1 - 1.3e-08 35.2 0.0 1.9e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFQ99288.1 - 0.011 15.7 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain FANCI_S1-cap PF14674.6 KFQ99288.1 - 0.86 9.7 4.8 6.2 7.0 0.0 2.3 2 0 0 2 2 2 0 FANCI solenoid 1 cap Thiolase_N PF00108.23 KFQ99289.1 - 7.1e-77 258.3 0.3 1.3e-76 257.4 0.3 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFQ99289.1 - 4.3e-50 168.5 0.0 9.2e-50 167.4 0.0 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFQ99289.1 - 7.5e-09 35.5 2.1 3.9e-08 33.2 0.2 2.7 3 1 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KFQ99289.1 - 0.42 10.5 2.6 2.8 7.8 0.2 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 3HCDH_N PF02737.18 KFQ99290.1 - 6e-57 192.4 1.6 1.3e-56 191.3 1.6 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 KFQ99290.1 - 1.2e-39 136.1 0.1 2.1e-39 135.4 0.1 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 KFQ99290.1 - 6e-26 90.9 1.7 7.6e-26 90.6 0.2 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 KFQ99290.1 - 7.8e-25 88.1 0.0 1.7e-24 86.9 0.0 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Ras PF00071.22 KFQ99291.1 - 9.4e-51 171.6 0.2 1.1e-50 171.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ99291.1 - 5.4e-22 78.3 0.1 8e-22 77.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ99291.1 - 1.8e-10 40.6 0.4 2.5e-10 40.1 0.3 1.2 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFQ99291.1 - 0.00011 21.8 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFQ99291.1 - 0.067 12.5 0.1 0.078 12.3 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF3963 PF13124.6 KFQ99291.1 - 0.12 12.3 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) Kinesin PF00225.23 KFQ99292.1 - 2.2e-119 398.3 0.0 2.2e-119 398.3 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFQ99292.1 - 8.9e-28 97.1 0.2 3.4e-27 95.2 0.0 2.2 2 1 1 3 3 3 1 Microtubule binding PIF1 PF05970.14 KFQ99292.1 - 0.00082 18.6 1.1 0.12 11.5 0.0 2.4 2 0 0 2 2 2 2 PIF1-like helicase Kinesin_assoc PF16183.5 KFQ99292.1 - 0.014 15.5 10.1 0.014 15.5 10.1 2.1 2 1 1 3 3 3 0 Kinesin-associated Fez1 PF06818.15 KFQ99292.1 - 0.016 15.7 12.4 0.016 15.7 12.4 2.8 3 0 0 3 3 3 0 Fez1 AAA_16 PF13191.6 KFQ99292.1 - 0.3 11.4 0.0 0.3 11.4 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain EF-hand_2 PF09068.11 KFQ99293.1 - 3.1e-35 121.0 1.9 7e-35 119.8 1.9 1.6 1 0 0 1 1 1 1 EF hand EF-hand_3 PF09069.11 KFQ99293.1 - 1.2e-30 105.8 0.1 2.8e-30 104.6 0.1 1.7 1 0 0 1 1 1 1 EF-hand ZZ PF00569.17 KFQ99293.1 - 5.9e-09 35.6 11.7 1.3e-08 34.5 11.7 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 KFQ99293.1 - 0.0032 17.8 10.7 0.0063 16.8 10.7 1.5 1 0 0 1 1 1 1 C1 domain CRISPR_Cse2 PF09485.10 KFQ99293.1 - 0.014 15.9 4.3 0.029 14.9 4.3 1.6 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) SOGA PF11365.8 KFQ99293.1 - 0.016 16.3 6.3 0.047 14.8 6.3 1.8 1 0 0 1 1 1 0 Protein SOGA FapA PF03961.13 KFQ99293.1 - 0.049 12.2 2.0 0.078 11.6 2.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Seryl_tRNA_N PF02403.22 KFQ99293.1 - 0.083 13.1 8.6 0.2 11.9 8.6 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ZapB PF06005.12 KFQ99293.1 - 1.4 9.4 19.0 1.4 9.4 16.1 2.6 2 1 0 2 2 2 0 Cell division protein ZapB MerR-DNA-bind PF09278.11 KFQ99293.1 - 2 9.0 12.0 2.9 8.5 10.4 2.2 1 1 1 2 2 2 0 MerR, DNA binding Nup54 PF13874.6 KFQ99293.1 - 9.2 6.4 13.9 23 5.1 13.9 1.6 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Na_H_Exchanger PF00999.21 KFQ99385.1 - 3.6e-83 279.5 30.6 8.1e-83 278.3 30.6 1.5 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Cobl PF09469.10 KFQ99388.1 - 1.7e-42 143.6 0.9 9e-42 141.3 0.3 2.2 2 0 0 2 2 2 1 Cordon-bleu ubiquitin-like domain RBD PF02196.15 KFQ99388.1 - 1.4e-06 28.3 2.0 0.00014 21.9 0.1 2.7 3 0 0 3 3 3 2 Raf-like Ras-binding domain Rad60-SLD PF11976.8 KFQ99388.1 - 0.0027 17.5 0.0 0.0055 16.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.8 KFQ99388.1 - 0.003 17.7 0.1 0.14 12.4 0.1 2.4 2 0 0 2 2 2 1 TUG ubiquitin-like domain Ubiquitin_5 PF18037.1 KFQ99388.1 - 0.12 12.8 0.1 0.54 10.7 0.0 2.1 1 1 0 1 1 1 0 Ubiquitin-like domain WH2 PF02205.20 KFQ99389.1 - 2.7e-16 58.8 4.8 0.00022 20.9 0.1 3.6 3 0 0 3 3 3 3 WH2 motif SH2 PF00017.24 KFQ99390.1 - 2.4e-15 56.4 0.0 5e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 SH2 domain BPS PF08947.10 KFQ99390.1 - 1.2e-14 53.8 3.2 6.9e-14 51.4 3.2 2.1 1 1 0 1 1 1 1 BPS (Between PH and SH2) RA PF00788.23 KFQ99390.1 - 6.8e-11 42.7 0.3 1.8e-10 41.3 0.1 1.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain PH PF00169.29 KFQ99390.1 - 7.3e-08 32.9 0.0 2.1e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KFQ99390.1 - 0.084 13.2 0.0 0.38 11.1 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain PRIMA1 PF16101.5 KFQ99424.1 - 7.4e-42 142.2 20.1 8.3e-42 142.0 20.1 1.0 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 KFQ99424.1 - 7.2 6.6 9.8 7.7 6.5 9.8 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator FAM181 PF15238.6 KFQ99425.1 - 4e-85 286.1 9.2 4.6e-85 285.9 9.2 1.0 1 0 0 1 1 1 1 FAM181 Ank_2 PF12796.7 KFQ99426.1 - 4.6e-67 222.6 26.1 3.1e-16 59.7 0.3 6.0 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ99426.1 - 7.9e-49 163.4 10.6 6e-10 39.5 0.1 8.6 5 3 4 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFQ99426.1 - 4e-44 143.5 12.9 0.00015 21.9 0.0 11.5 11 0 0 11 11 11 9 Ankyrin repeat Ank PF00023.30 KFQ99426.1 - 1.3e-32 110.8 17.2 0.0019 18.6 0.0 11.0 9 2 2 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 KFQ99426.1 - 6.2e-30 102.9 14.7 3.9e-09 36.6 0.2 9.2 3 2 8 11 11 11 9 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFQ99426.1 - 3e-09 37.1 6.6 6.5e-09 36.0 6.6 1.6 1 0 0 1 1 1 1 SOCS box UIM PF02809.20 KFQ99426.1 - 0.076 13.0 3.3 0.15 12.0 3.3 1.5 1 0 0 1 1 1 0 Ubiquitin interaction motif Serpin PF00079.20 KFQ99427.1 - 6.9e-121 404.0 5.0 7.7e-121 403.9 5.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) FSH1 PF03959.13 KFQ99427.1 - 0.033 13.8 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Serpin PF00079.20 KFQ99428.1 - 1.5e-122 409.5 2.9 1.7e-122 409.4 2.9 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFQ99429.1 - 4.8e-118 394.7 0.7 5.3e-118 394.5 0.7 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFQ99430.1 - 8.4e-114 380.7 0.2 9.4e-114 380.6 0.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF2100 PF09873.9 KFQ99430.1 - 0.13 12.1 0.2 0.29 11.0 0.2 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2100) Serpin PF00079.20 KFQ99431.1 - 2.4e-110 369.3 0.2 2.7e-110 369.2 0.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF4198 PF10670.9 KFQ99431.1 - 0.0023 18.4 0.0 0.0035 17.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4198) Homeodomain PF00046.29 KFQ99432.1 - 2.6e-23 81.6 5.6 4.9e-23 80.7 5.6 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ99432.1 - 0.00083 19.2 0.1 0.0018 18.1 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain DUF3437 PF11919.8 KFQ99432.1 - 0.18 11.8 2.6 0.99 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Ribonuclease_3 PF00636.26 KFQ99433.1 - 1.1e-69 231.6 1.5 7.3e-44 148.7 0.0 3.4 3 1 0 3 3 3 2 Ribonuclease III domain PAZ PF02170.22 KFQ99433.1 - 8.4e-40 135.8 0.6 5.2e-39 133.2 0.2 2.5 2 0 0 2 2 2 1 PAZ domain Ribonucleas_3_3 PF14622.6 KFQ99433.1 - 6.9e-25 87.7 0.0 1.5e-16 60.7 0.0 3.8 3 1 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.14 KFQ99433.1 - 1.8e-24 85.7 0.1 7.1e-24 83.8 0.0 2.2 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 KFQ99433.1 - 4.2e-18 65.7 0.1 1.8e-17 63.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFQ99433.1 - 7.9e-14 52.0 0.0 2.4e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFQ99433.1 - 3.3e-13 49.8 0.3 7.7e-13 48.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.9 KFQ99433.1 - 0.01 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) dsrm PF00035.26 KFQ99433.1 - 0.081 13.6 0.0 0.36 11.6 0.0 2.2 1 0 0 1 1 1 0 Double-stranded RNA binding motif Flavi_DEAD PF07652.14 KFQ99433.1 - 0.15 12.1 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 0 Flavivirus DEAD domain CH PF00307.31 KFQ99435.1 - 8.8e-38 128.8 0.3 9.1e-21 74.1 0.0 2.1 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFQ99435.1 - 5.9e-07 29.2 0.0 0.0093 15.8 0.0 2.6 2 0 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.11 KFQ99435.1 - 0.036 14.2 0.1 0.73 10.0 0.0 2.2 2 0 0 2 2 2 0 CH-like domain in sperm protein RcsD_ABL PF16359.5 KFQ99435.1 - 0.045 13.9 0.0 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 RcsD-ABL domain KASH PF10541.9 KFQ99436.1 - 5.9e-25 87.3 8.3 1.1e-24 86.4 8.3 1.5 1 0 0 1 1 1 1 Nuclear envelope localisation domain Spectrin PF00435.21 KFQ99436.1 - 4.5e-13 49.6 84.0 1.7e-05 25.2 4.3 8.8 6 1 3 9 9 9 6 Spectrin repeat SnoaL PF07366.12 KFQ99436.1 - 0.047 13.5 0.5 57 3.5 0.1 4.1 4 0 0 4 4 4 0 SnoaL-like polyketide cyclase Gamma-thionin PF00304.20 KFQ99436.1 - 0.069 13.4 0.6 0.15 12.4 0.6 1.4 1 0 0 1 1 1 0 Gamma-thionin family DASH_Dad1 PF08649.10 KFQ99436.1 - 0.097 12.9 8.5 9.4 6.5 0.1 5.1 4 0 0 4 4 4 0 DASH complex subunit Dad1 CTD_bind PF04818.13 KFQ99436.1 - 0.16 12.8 2.8 14 6.6 0.0 4.3 4 0 0 4 4 4 0 RNA polymerase II-binding domain. IL4 PF00727.18 KFQ99436.1 - 3.3 8.0 7.3 1.2 9.4 0.1 3.7 4 0 0 4 4 4 0 Interleukin 4 Glutaredoxin PF00462.24 KFQ99438.1 - 2.1e-05 24.6 0.2 0.00021 21.4 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin DUF2639 PF11121.8 KFQ99438.1 - 0.082 12.9 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2639) 7tm_1 PF00001.21 KFQ99439.1 - 1e-49 169.2 26.8 1.3e-49 168.9 26.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1275 PF06912.11 KFQ99439.1 - 0.13 12.1 5.8 0.15 12.0 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1275) DUF2070 PF09843.9 KFQ99439.1 - 0.9 7.7 5.4 0.11 10.7 1.5 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF727 PF05303.12 KFQ99440.1 - 4.9e-32 110.1 0.0 6e-32 109.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF727) Dpy-30 PF05186.13 KFQ99441.1 - 2.3e-19 68.8 0.3 3e-18 65.2 0.0 2.5 3 0 0 3 3 2 1 Dpy-30 motif ADK PF00406.22 KFQ99441.1 - 3.4e-13 49.9 0.2 3.4e-10 40.2 0.1 3.2 1 1 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.6 KFQ99441.1 - 2.8e-08 34.4 3.0 6.6e-07 29.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KFQ99441.1 - 1.6e-07 31.8 0.5 1.6e-07 31.8 0.5 3.3 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 KFQ99441.1 - 3.2e-05 24.4 0.0 8.2e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Hydin_ADK PF17213.3 KFQ99441.1 - 4.2e-05 23.9 4.3 9e-05 22.8 0.0 2.8 3 0 0 3 3 3 1 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 KFQ99441.1 - 6.3e-05 23.2 0.4 0.00015 21.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KFQ99441.1 - 7.3e-05 23.2 1.5 0.00017 22.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 KFQ99441.1 - 0.00062 20.1 0.0 0.0024 18.2 0.0 2.1 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 KFQ99441.1 - 0.00094 19.5 0.0 0.00094 19.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KFQ99441.1 - 0.0026 17.0 0.0 0.0063 15.7 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain RIIa PF02197.17 KFQ99441.1 - 0.0048 16.5 0.2 0.032 13.9 0.0 2.4 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit AAA_22 PF13401.6 KFQ99441.1 - 0.0086 16.4 0.0 0.037 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KFQ99441.1 - 0.015 15.2 0.0 0.035 14.0 0.0 1.7 1 0 0 1 1 1 0 NTPase Ploopntkinase3 PF18751.1 KFQ99441.1 - 0.016 15.1 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 RuvB_N PF05496.12 KFQ99441.1 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KFQ99441.1 - 0.021 14.8 0.1 0.081 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 KFQ99441.1 - 0.021 15.3 0.7 0.062 13.8 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 KFQ99441.1 - 0.032 13.9 0.0 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 KFQ99441.1 - 0.046 13.2 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_14 PF13173.6 KFQ99441.1 - 0.05 13.6 0.4 0.61 10.1 0.0 2.8 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KFQ99441.1 - 0.068 12.9 0.1 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 KFQ99441.1 - 0.095 12.5 4.5 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KFQ99441.1 - 0.1 12.7 0.0 0.42 10.7 0.0 2.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRP54_N PF02881.19 KFQ99441.1 - 0.14 12.4 2.3 1.5 9.1 0.1 3.2 3 0 0 3 3 2 0 SRP54-type protein, helical bundle domain Cytidylate_kin2 PF13189.6 KFQ99441.1 - 0.16 12.1 1.2 0.64 10.1 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase-like family GBP_C PF02841.14 KFQ99441.1 - 0.16 11.4 14.1 3.1 7.1 9.1 2.2 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain SKI PF01202.22 KFQ99441.1 - 0.19 11.8 3.8 0.29 11.2 0.0 2.7 3 0 0 3 3 2 0 Shikimate kinase DUF1682 PF07946.14 KFQ99441.1 - 0.25 10.5 5.5 0.41 9.8 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) HSP70 PF00012.20 KFQ99441.1 - 1.3 7.1 5.5 2.7 6.1 5.5 1.4 1 0 0 1 1 1 0 Hsp70 protein PAP_central PF04928.17 KFQ99442.1 - 1.4e-116 387.8 0.0 3e-116 386.7 0.0 1.6 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KFQ99442.1 - 1.9e-25 89.5 5.1 5.9e-19 68.3 0.0 2.9 2 1 1 3 3 3 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KFQ99442.1 - 8.5e-14 51.6 0.0 2e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Pkinase PF00069.25 KFQ99443.1 - 5.2e-14 52.2 0.0 8.8e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ99443.1 - 2.9e-08 33.3 0.4 1.2e-07 31.3 0.1 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFQ99443.1 - 0.0032 16.3 0.1 0.015 14.1 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFQ99443.1 - 0.017 15.0 0.1 0.11 12.4 0.0 2.2 3 0 0 3 3 3 0 Phosphotransferase enzyme family EcKinase PF02958.20 KFQ99443.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Kinase-like PF14531.6 KFQ99443.1 - 0.089 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like zf-C2H2 PF00096.26 KFQ99445.1 - 4.1e-26 89.9 53.8 5.2e-06 26.6 2.8 7.4 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ99445.1 - 2.7e-16 58.9 50.4 0.0019 18.9 0.9 7.5 7 0 0 7 7 7 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFQ99445.1 - 7.2e-16 57.8 44.1 2.9e-07 30.6 1.3 7.7 7 0 0 7 7 7 4 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFQ99445.1 - 5.1e-05 22.9 34.4 9e-05 22.1 3.9 4.6 5 0 0 5 5 5 2 C2H2-type zinc-finger domain DUF3268 PF11672.8 KFQ99445.1 - 0.00073 19.9 15.8 0.013 15.8 1.2 2.7 2 1 1 3 3 3 2 zinc-finger-containing domain zf-C2H2_7 PF15269.6 KFQ99445.1 - 0.009 16.1 13.0 0.36 11.0 0.5 3.7 3 0 0 3 3 3 2 Zinc-finger FYVE PF01363.21 KFQ99445.1 - 0.013 15.6 25.2 0.2 11.8 0.5 5.3 5 0 0 5 5 5 0 FYVE zinc finger GAGA PF09237.11 KFQ99445.1 - 0.07 12.9 7.9 1.7 8.5 0.6 3.0 2 1 0 2 2 2 0 GAGA factor Actin_micro PF17003.5 KFQ99445.1 - 0.26 10.4 9.0 2.3 7.3 0.4 3.7 3 1 1 4 4 4 0 Putative actin-like family zf-FCS PF06467.14 KFQ99445.1 - 0.82 9.7 12.5 3 7.9 0.1 4.2 4 0 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_jaz PF12171.8 KFQ99445.1 - 2.4 8.5 44.6 0.93 9.9 1.9 6.2 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding DUF2256 PF10013.9 KFQ99445.1 - 8.2 6.6 14.6 14 5.9 0.5 4.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) Rubis-subs-bind PF09273.11 KFQ99446.1 - 4.7e-29 101.7 0.1 1.1e-28 100.5 0.1 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 KFQ99446.1 - 3.2e-13 50.4 1.7 4.3e-13 50.0 0.0 2.1 2 1 0 2 2 2 1 SET domain Cyclin_N PF00134.23 KFQ99447.1 - 6.7e-14 51.7 0.0 6.7e-14 51.7 0.0 2.4 3 0 0 3 3 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFQ99447.1 - 0.00014 21.9 0.1 0.00014 21.9 0.1 2.3 1 1 1 2 2 1 1 Cyclin, C-terminal domain DAG_kinase_N PF14513.6 KFQ99447.1 - 0.0081 16.4 6.1 0.015 15.5 6.1 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase N-terminus DDHD PF02862.17 KFQ99447.1 - 0.021 15.0 4.7 0.038 14.2 4.7 1.4 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 KFQ99447.1 - 0.065 13.0 10.5 0.098 12.5 10.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAR2 PF05282.11 KFQ99447.1 - 0.47 9.8 7.4 0.67 9.3 7.4 1.1 1 0 0 1 1 1 0 AAR2 protein Presenilin PF01080.17 KFQ99447.1 - 1.4 7.6 13.9 2 7.1 13.9 1.1 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 KFQ99447.1 - 2 7.3 10.0 2.9 6.8 10.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Lin-8 PF03353.15 KFQ99447.1 - 3.4 7.2 16.8 5 6.6 16.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4834 PF16118.5 KFQ99447.1 - 5.1 8.1 9.8 9.8 7.2 9.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Neur_chan_memb PF02932.16 KFQ99447.1 - 6.6 6.7 10.0 11 6.0 10.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.13 KFQ99447.1 - 7.8 6.2 9.2 12 5.6 9.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CobT PF06213.12 KFQ99447.1 - 9.1 5.6 14.7 17 4.6 14.7 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CCDC85 PF10226.9 KFQ99448.1 - 8.3e-95 316.0 13.9 2.2e-94 314.6 13.9 1.7 1 0 0 1 1 1 1 CCDC85 family AMH_N PF04709.12 KFQ99448.1 - 0.0033 16.4 1.1 0.0057 15.6 1.1 1.3 1 0 0 1 1 1 1 Anti-Mullerian hormone, N terminal region TSC22 PF01166.18 KFQ99448.1 - 0.074 13.4 17.8 3.2 8.2 0.1 4.5 3 1 1 4 4 4 0 TSC-22/dip/bun family DUF4577 PF15145.6 KFQ99448.1 - 0.12 12.4 1.3 0.2 11.7 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) bZIP_1 PF00170.21 KFQ99448.1 - 0.26 11.4 0.2 0.26 11.4 0.2 4.7 4 1 1 5 5 5 0 bZIP transcription factor Shugoshin_N PF07558.11 KFQ99448.1 - 7.9 6.4 13.2 0.14 12.1 1.6 3.3 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region GSDH PF07995.11 KFQ99449.1 - 8.9e-39 133.7 0.0 1.2e-38 133.3 0.0 1.1 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Folate_rec PF03024.14 KFQ99449.1 - 5.9e-07 29.5 1.1 5.9e-07 29.5 1.1 1.6 2 0 0 2 2 2 1 Folate receptor family p450 PF00067.22 KFQ99450.1 - 2.3e-91 306.9 0.3 2.8e-91 306.6 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 Rab5-bind PF09311.11 KFQ99450.1 - 0.074 12.4 1.0 0.085 12.2 0.1 1.4 2 0 0 2 2 2 0 Rabaptin-like protein Sulfotransfer_2 PF03567.14 KFQ99450.1 - 0.091 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase family PIP49_C PF12260.8 KFQ99451.1 - 1.4e-05 24.8 0.1 2.6e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 PAN_4 PF14295.6 KFQ99451.1 - 0.23 11.4 2.3 0.48 10.4 0.2 2.2 2 0 0 2 2 2 0 PAN domain Nodulin_late PF07127.11 KFQ99451.1 - 0.53 10.7 3.9 1 9.7 1.4 2.2 2 0 0 2 2 2 0 Late nodulin protein HELP PF03451.14 KFQ99452.1 - 1.6e-31 108.0 0.1 3.1e-31 107.0 0.1 1.5 1 0 0 1 1 1 1 HELP motif WD40 PF00400.32 KFQ99452.1 - 1.3e-27 95.5 41.1 0.00021 22.0 0.8 10.7 10 1 0 10 10 10 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ99452.1 - 2.1e-06 27.9 0.2 0.00065 19.9 0.0 4.6 3 2 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain PKcGMP_CC PF16808.5 KFQ99452.1 - 0.048 13.5 0.2 0.098 12.5 0.2 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DPPIV_N PF00930.21 KFQ99452.1 - 0.05 12.3 0.0 0.12 11.1 0.0 1.6 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region SlyX PF04102.12 KFQ99452.1 - 0.67 10.6 2.5 0.73 10.5 1.3 1.7 2 0 0 2 2 2 0 SlyX FA_desaturase PF00487.24 KFQ99453.1 - 1.9e-25 90.1 17.9 3.4e-25 89.3 17.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 KFQ99453.1 - 6.8e-06 25.5 0.3 1.8e-05 24.1 0.3 1.8 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) zf-C2H2 PF00096.26 KFQ99454.1 - 3.1e-19 68.3 23.3 8.9e-06 25.9 0.4 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ99454.1 - 1.1e-16 60.4 21.7 2.5e-07 30.8 0.2 4.8 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ99454.1 - 2.7e-13 49.5 20.5 0.01 16.6 0.2 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KFQ99454.1 - 0.00055 20.1 6.4 1.5 8.9 0.1 3.2 1 1 2 3 3 3 2 Aberrant zinc-finger IBR PF01485.21 KFQ99454.1 - 0.0064 16.7 6.7 0.0087 16.3 1.6 2.6 1 1 1 2 2 2 1 IBR domain, a half RING-finger domain zf-TRAF PF02176.18 KFQ99454.1 - 0.0066 17.1 12.3 2.6 8.8 0.1 3.3 1 1 2 3 3 3 2 TRAF-type zinc finger Transpos_assoc PF13963.6 KFQ99454.1 - 0.0085 16.4 5.6 0.29 11.5 0.1 3.2 2 1 1 3 3 3 1 Transposase-associated domain Raffinose_syn PF05691.12 KFQ99454.1 - 0.011 13.6 0.0 0.014 13.3 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 CHORD PF04968.12 KFQ99454.1 - 0.014 16.1 11.6 4.3 8.1 2.1 3.7 1 1 3 4 4 4 0 CHORD zinc_ribbon_9 PF14369.6 KFQ99454.1 - 0.021 15.1 3.1 0.94 9.8 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon CCAP PF11105.8 KFQ99454.1 - 0.023 14.6 4.5 0.39 10.7 0.7 2.3 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a zf_UBZ PF18439.1 KFQ99454.1 - 0.03 13.9 0.9 1.5 8.5 0.2 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 KFQ99454.1 - 0.034 14.4 12.0 4 7.8 0.4 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-CGNR PF11706.8 KFQ99454.1 - 0.043 13.7 6.9 3 7.8 0.8 3.4 3 1 0 3 3 3 0 CGNR zinc finger zf-C2H2_11 PF16622.5 KFQ99454.1 - 0.087 12.6 7.2 1.6 8.5 0.4 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 KFQ99454.1 - 0.32 11.5 6.5 4.2 7.9 0.3 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type XPA_N PF01286.18 KFQ99454.1 - 0.53 10.4 4.6 1.5 9.0 0.1 3.0 4 0 0 4 4 3 0 XPA protein N-terminal FOXP-CC PF16159.5 KFQ99454.1 - 2.6 8.7 7.8 11 6.8 1.9 2.9 3 1 0 3 3 3 0 FOXP coiled-coil domain Mito_carr PF00153.27 KFQ99455.1 - 6.3e-55 183.1 2.5 6.1e-23 80.6 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 KFQ99455.1 - 0.26 11.7 1.5 2.4 8.6 0.1 2.8 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Mito_carr PF00153.27 KFQ99456.1 - 6.5e-68 224.7 0.5 2.3e-23 81.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 KFQ99456.1 - 0.041 14.3 4.6 0.23 11.9 2.3 2.8 2 2 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family tRNA-synt_1b PF00579.25 KFQ99457.1 - 5.5e-23 81.7 0.0 9.7e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) WHEP-TRS PF00458.20 KFQ99457.1 - 2.6e-21 75.5 0.1 6.3e-21 74.3 0.1 1.7 1 0 0 1 1 1 1 WHEP-TRS domain Hemopexin PF00045.19 KFQ99464.1 - 1.4e-20 73.0 0.7 3.1e-09 36.6 0.1 3.3 3 1 0 3 3 3 3 Hemopexin Metallophos PF00149.28 KFQ99465.1 - 0.016 15.7 1.9 0.055 14.0 0.7 2.1 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase 7tm_1 PF00001.21 KFQ99466.1 - 2.5e-63 213.9 4.0 3.1e-63 213.6 4.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ99466.1 - 7.2e-09 35.4 12.0 1.9e-05 24.2 5.4 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFQ99466.1 - 8.5e-08 32.3 9.8 2e-07 31.0 9.8 1.7 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srw PF10324.9 KFQ99466.1 - 5.7e-06 25.8 9.9 0.031 13.5 6.8 2.5 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 KFQ99466.1 - 0.00024 20.9 11.4 0.00024 20.9 11.4 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srh PF10318.9 KFQ99466.1 - 0.0015 17.7 6.6 0.0015 17.7 6.6 2.8 3 1 1 4 4 4 1 Serpentine type 7TM GPCR chemoreceptor Srh Git3 PF11710.8 KFQ99466.1 - 0.072 12.9 7.9 0.012 15.4 4.1 1.8 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 CRCB PF02537.15 KFQ99466.1 - 1.2 9.5 7.9 0.44 10.9 4.5 2.2 2 0 0 2 2 2 0 CrcB-like protein, Camphor Resistance (CrcB) Lig_chan PF00060.26 KFQ99466.1 - 2.8 7.8 4.8 7.7 6.3 0.4 2.5 2 0 0 2 2 2 0 Ligand-gated ion channel Peptidase_U4 PF03419.13 KFQ99466.1 - 9.4 5.4 8.1 94 2.1 8.0 2.2 1 1 0 1 1 1 0 Sporulation factor SpoIIGA RAI16-like PF10257.9 KFQ99467.1 - 2.1e-68 230.9 13.5 5.9e-42 143.8 2.7 2.1 2 0 0 2 2 2 2 Retinoic acid induced 16-like protein Ribosomal_S17 PF00366.20 KFQ99468.1 - 4.3e-29 100.4 1.6 5.6e-29 100.1 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 KFQ99468.1 - 1.3e-13 51.1 0.1 1.3e-13 51.1 0.1 2.1 3 0 0 3 3 3 1 Ribosomal_S17 N-terminal PRF PF06875.11 KFQ99468.1 - 0.051 13.0 0.1 0.08 12.4 0.1 1.2 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF 7tm_4 PF13853.6 KFQ99469.1 - 4.5e-109 364.5 19.3 5.2e-109 364.3 19.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ99469.1 - 2.2e-28 99.3 16.4 3e-28 98.9 16.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ99469.1 - 3.1e-11 43.1 8.9 3.1e-11 43.1 8.9 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx ubiquitin PF00240.23 KFQ99470.1 - 2.2e-16 59.3 1.7 4.3e-16 58.4 1.7 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KFQ99470.1 - 9.3e-05 22.2 0.9 0.00023 20.9 0.9 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 KFQ99470.1 - 0.00043 20.1 0.5 0.0012 18.8 0.5 1.8 1 0 0 1 1 1 1 UBA/TS-N domain STI1 PF17830.1 KFQ99470.1 - 0.0018 18.2 2.1 0.031 14.2 0.2 3.4 3 1 0 3 3 3 1 STI1 domain Ubiquitin_5 PF18037.1 KFQ99470.1 - 0.018 15.4 1.5 0.018 15.4 1.5 1.8 2 0 0 2 2 2 0 Ubiquitin-like domain HOIP-UBA PF16678.5 KFQ99470.1 - 0.033 14.2 0.1 0.064 13.3 0.1 1.5 1 0 0 1 1 1 0 HOIP UBA domain pair ATG2_CAD PF13329.6 KFQ99470.1 - 0.065 13.0 0.1 0.66 9.7 0.1 2.2 2 0 0 2 2 2 0 Autophagy-related protein 2 CAD motif Rad60-SLD_2 PF13881.6 KFQ99470.1 - 0.086 12.9 0.1 0.25 11.4 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CPL PF08144.11 KFQ99470.1 - 0.11 12.8 0.6 0.3 11.4 0.6 1.7 1 0 0 1 1 1 0 CPL (NUC119) domain 7tm_4 PF13853.6 KFQ99471.1 - 3.3e-116 387.9 26.2 4e-116 387.6 26.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ99471.1 - 2.3e-28 99.2 22.5 3e-28 98.9 22.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ99471.1 - 1.1e-09 38.0 20.1 1.6e-09 37.5 20.1 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFQ99471.1 - 0.003 17.2 12.0 0.003 17.2 12.0 1.9 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Folate_rec PF03024.14 KFQ99472.1 - 8.5e-64 214.6 24.2 1e-63 214.3 24.2 1.1 1 0 0 1 1 1 1 Folate receptor family 7tm_4 PF13853.6 KFQ99473.1 - 3.4e-108 361.6 21.9 4e-108 361.4 21.9 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ99473.1 - 1.5e-24 86.8 19.5 2.1e-24 86.3 19.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ99473.1 - 2.3e-09 37.0 17.9 3.1e-09 36.6 17.9 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF1418 PF07214.12 KFQ99473.1 - 0.15 11.9 2.6 0.77 9.7 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1418) 7TM_GPCR_Srx PF10328.9 KFQ99473.1 - 0.16 11.6 18.1 0.015 14.9 13.5 1.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Globin PF00042.22 KFQ99474.1 - 2e-30 105.6 0.0 4.3e-30 104.5 0.0 1.5 2 0 0 2 2 2 1 Globin Globin PF00042.22 KFQ99475.1 - 1.1e-30 106.4 0.1 2.2e-30 105.5 0.0 1.5 2 0 0 2 2 2 1 Globin Globin PF00042.22 KFQ99476.1 - 9.5e-31 106.6 0.0 1.6e-30 105.8 0.0 1.4 2 0 0 2 2 2 1 Globin Globin PF00042.22 KFQ99477.1 - 3.1e-18 66.4 0.2 5.9e-18 65.4 0.0 1.5 2 0 0 2 2 2 1 Globin Big_8 PF17961.1 KFQ99477.1 - 0.17 12.1 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial Ig domain Globin PF00042.22 KFQ99478.1 - 4.2e-31 107.8 0.0 6e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Globin 7tm_4 PF13853.6 KFQ99479.1 - 1.7e-104 349.5 27.5 1.9e-104 349.3 27.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ99479.1 - 1.9e-22 79.8 19.2 2.5e-22 79.5 19.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ99479.1 - 4.5e-05 23.0 18.1 0.00013 21.4 18.1 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFQ99480.1 - 1e-104 350.2 23.1 1.2e-104 350.0 23.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ99480.1 - 3.9e-19 69.0 23.3 1.2e-18 67.4 23.3 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ99480.1 - 8.4e-08 31.9 5.3 8.4e-08 31.9 5.3 1.8 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx T4SS_CagC PF16943.5 KFQ99480.1 - 6.3 7.0 10.1 1.2 9.4 0.4 2.9 3 1 1 4 4 4 0 Cag pathogenicity island, type IV secretory system 7tm_4 PF13853.6 KFQ99481.1 - 6.3e-118 393.5 25.4 7.2e-118 393.4 25.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ99481.1 - 6e-23 81.5 20.3 7.8e-23 81.1 20.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ99481.1 - 1.1e-06 28.2 22.6 2.3e-06 27.2 22.6 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFQ99482.1 - 5.9e-103 344.4 14.7 6.7e-103 344.2 14.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ99482.1 - 5.3e-20 71.9 14.8 6.9e-20 71.5 14.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ99482.1 - 8e-08 32.0 9.7 1e-07 31.6 9.7 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFQ99483.1 - 2e-98 329.6 16.4 2.2e-98 329.4 16.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFQ99483.1 - 6.9e-24 84.6 12.1 8.8e-24 84.2 12.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ99483.1 - 6.9e-10 38.7 10.6 1.4e-09 37.7 10.6 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srbc PF10316.9 KFQ99483.1 - 5.1e-05 22.9 7.5 8.1e-05 22.3 7.5 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srx PF10328.9 KFQ99483.1 - 0.0088 15.7 8.9 0.0088 15.7 8.9 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Ribonuc_red_lgC PF02867.15 KFQ99484.1 - 2.3e-167 557.7 0.0 1.1e-137 459.8 0.0 2.1 2 0 0 2 2 2 2 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KFQ99484.1 - 9.7e-23 80.0 0.0 2.5e-22 78.6 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KFQ99484.1 - 1.5e-13 51.1 0.0 3.6e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 ATP cone domain DUF498 PF04430.14 KFQ99484.1 - 0.0091 16.0 0.1 5.9 7.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF498/DUF598) SNF PF00209.18 KFQ99485.1 - 7e-67 226.3 4.6 7.9e-67 226.1 4.6 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family AA_permease_2 PF13520.6 KFQ99485.1 - 0.0054 15.6 4.7 0.0063 15.4 4.7 1.1 1 0 0 1 1 1 1 Amino acid permease SOAR PF16533.5 KFQ99486.1 - 2.5e-43 146.2 2.9 2.5e-43 146.2 2.9 3.2 3 1 0 3 3 3 1 STIM1 Orai1-activating region Noelin-1 PF12308.8 KFQ99486.1 - 1.3 9.1 5.1 1.5 8.8 0.5 2.6 1 1 1 2 2 2 0 Neurogenesis glycoprotein DUF2564 PF10819.8 KFQ99486.1 - 3.8 8.0 12.7 11 6.5 2.7 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2564) Ribosomal_S20p PF01649.18 KFQ99486.1 - 6.4 7.5 9.1 1 10.0 0.5 2.8 2 1 0 2 2 2 0 Ribosomal protein S20 NHL PF01436.21 KFQ99524.1 - 3.8e-39 130.8 18.7 4.5e-08 32.7 0.7 5.9 6 0 0 6 6 5 5 NHL repeat Filamin PF00630.19 KFQ99524.1 - 7.6e-20 71.7 0.0 2.8e-19 69.8 0.0 2.0 1 0 0 1 1 1 1 Filamin/ABP280 repeat DUF5128 PF17170.4 KFQ99524.1 - 9.3e-15 54.6 4.4 8.7e-05 21.8 0.0 3.8 1 1 1 3 3 3 3 6-bladed beta-propeller SGL PF08450.12 KFQ99524.1 - 3.8e-10 39.8 3.7 0.009 15.6 0.2 4.5 1 1 3 4 4 4 3 SMP-30/Gluconolactonase/LRE-like region zf-RING_UBOX PF13445.6 KFQ99524.1 - 1.2e-09 38.0 5.9 1.2e-09 38.0 5.9 2.6 2 1 1 3 3 3 1 RING-type zinc-finger zf-B_box PF00643.24 KFQ99524.1 - 5.5e-08 32.8 0.9 5.5e-08 32.8 0.9 2.9 3 1 0 3 3 2 1 B-box zinc finger zf-C3HC4_3 PF13920.6 KFQ99524.1 - 7.3e-08 32.2 7.3 7.3e-08 32.2 7.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ99524.1 - 1.1e-07 31.6 9.2 1.1e-07 31.6 9.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFQ99524.1 - 1.2e-07 31.5 9.2 1.2e-07 31.5 9.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFQ99524.1 - 1.3e-07 31.5 7.5 1.3e-07 31.5 7.5 2.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFQ99524.1 - 7.6e-07 29.4 9.1 7.6e-07 29.4 9.1 2.5 2 0 0 2 2 2 1 Ring finger domain DUF4934 PF16288.5 KFQ99524.1 - 1.4e-06 28.2 0.2 0.0069 16.3 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4934) Prok-RING_4 PF14447.6 KFQ99524.1 - 3.3e-05 23.6 8.2 3.3e-05 23.6 8.2 2.9 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFQ99524.1 - 0.00018 21.6 11.4 0.00018 21.6 11.4 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Invasin_D3 PF09134.10 KFQ99524.1 - 0.00031 21.0 0.0 0.0011 19.2 0.0 1.9 1 0 0 1 1 1 1 Invasin, domain 3 SBBP PF06739.11 KFQ99524.1 - 0.0052 16.7 1.0 10 6.2 0.4 3.5 3 0 0 3 3 3 0 Beta-propeller repeat zf-ANAPC11 PF12861.7 KFQ99524.1 - 0.0083 16.2 0.9 0.017 15.1 0.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KFQ99524.1 - 0.014 15.1 2.1 0.029 14.1 1.1 2.1 1 1 0 1 1 1 0 RING-like zinc finger YtkA PF13115.6 KFQ99524.1 - 0.049 14.2 0.0 0.18 12.4 0.0 1.9 2 0 0 2 2 1 0 YtkA-like VCBS PF13517.6 KFQ99524.1 - 1.4 9.6 7.4 21 5.8 1.0 4.1 2 1 3 5 5 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella zf-RING_10 PF16685.5 KFQ99524.1 - 4.2 7.6 11.1 1.5 9.0 4.4 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 Arfaptin PF06456.13 KFQ99525.1 - 9.6e-80 267.4 8.5 1.1e-79 267.3 8.5 1.0 1 0 0 1 1 1 1 Arfaptin-like domain BAR PF03114.18 KFQ99525.1 - 4.5e-06 26.5 10.6 7.9e-06 25.7 10.6 1.4 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 KFQ99525.1 - 0.088 12.5 11.7 0.19 11.4 11.3 1.6 1 1 0 1 1 1 0 BAR domain of APPL family BAR_2 PF10455.9 KFQ99525.1 - 0.13 11.4 5.0 0.12 11.5 3.9 1.3 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking zf-Tim10_DDP PF02953.15 KFQ99526.1 - 9.6e-13 47.6 0.2 1.3e-12 47.2 0.2 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger WD40 PF00400.32 KFQ99527.1 - 2.8e-17 62.8 11.7 3.8e-08 33.8 0.2 3.9 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ99527.1 - 5.1e-10 39.5 0.3 0.0022 18.3 0.0 3.3 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFQ99527.1 - 5.3e-09 35.3 2.3 0.044 12.4 0.0 3.5 1 1 3 4 4 4 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KFQ99527.1 - 0.00023 20.2 2.5 0.0093 14.9 0.1 2.8 1 1 2 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 KFQ99527.1 - 0.00078 18.5 1.1 0.13 11.2 1.0 3.0 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KFQ99527.1 - 0.0022 17.6 0.6 0.0087 15.7 0.1 2.1 1 1 1 2 2 2 1 PQQ-like domain Hira PF07569.11 KFQ99527.1 - 0.01 15.5 0.6 2.1 8.0 0.0 2.9 1 1 2 3 3 3 0 TUP1-like enhancer of split CDtoxinA PF03498.14 KFQ99527.1 - 0.032 13.8 0.1 0.049 13.2 0.1 1.3 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain BBS2_Mid PF14783.6 KFQ99527.1 - 0.086 12.9 0.1 1.8 8.7 0.0 2.5 1 1 2 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.21 KFQ99527.1 - 0.094 12.7 0.2 25 5.0 0.0 3.7 4 1 1 5 5 5 0 PQQ enzyme repeat Retinal PF15449.6 KFQ99528.1 - 0.095 10.5 4.2 0.11 10.2 4.2 1.0 1 0 0 1 1 1 0 Retinal protein Methyltransf_8 PF05148.15 KFQ99529.1 - 4.4e-81 271.9 0.0 4.8e-81 271.8 0.0 1.0 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KFQ99529.1 - 2.2e-08 34.6 0.1 8.8e-08 32.7 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFQ99529.1 - 4.7e-06 27.2 0.1 0.00069 20.3 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFQ99529.1 - 1.1e-05 25.2 0.1 0.00021 21.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KFQ99529.1 - 0.00081 19.0 0.1 0.83 9.2 0.1 2.2 1 1 1 2 2 2 2 Methyltransferase small domain Methyltransf_23 PF13489.6 KFQ99529.1 - 0.0038 17.1 0.0 0.046 13.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFQ99529.1 - 0.013 14.8 0.0 0.042 13.2 0.0 1.8 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KFQ99529.1 - 0.016 15.9 0.2 1.3 9.8 0.0 2.7 2 1 1 3 3 3 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KFQ99529.1 - 0.088 12.0 0.2 0.12 11.5 0.2 1.1 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Pkinase_Tyr PF07714.17 KFQ99530.1 - 2.2e-33 115.7 0.0 3.3e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_5 PF13857.6 KFQ99530.1 - 3.6e-24 84.5 2.2 3.7e-11 43.0 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFQ99530.1 - 9.7e-23 79.6 0.3 8.1e-06 26.1 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KFQ99530.1 - 1.6e-20 71.0 0.2 6.3e-06 26.1 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 KFQ99530.1 - 6.9e-20 71.4 0.0 5.3e-12 46.2 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFQ99530.1 - 7.9e-20 71.0 0.6 1.9e-10 41.0 0.1 3.2 1 1 1 3 3 3 2 Ankyrin repeats (many copies) Pkinase PF00069.25 KFQ99530.1 - 1.2e-17 64.1 0.0 2e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TFIID_30kDa PF03540.13 KFQ99531.1 - 4.8e-27 93.7 0.0 6.9e-27 93.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 KFQ99531.1 - 0.00065 19.7 0.0 0.011 15.7 0.0 2.1 1 1 0 1 1 1 1 Bromodomain associated Pro-kuma_activ PF09286.11 KFQ99532.1 - 2.1e-20 73.5 0.0 3.3e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain GRASP55_65 PF04495.14 KFQ99535.1 - 2.4e-72 241.7 0.0 4.7e-56 188.9 0.0 2.3 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 KFQ99535.1 - 6.1e-08 32.9 0.0 0.00028 21.2 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFQ99535.1 - 1.2e-06 28.2 0.2 0.071 13.0 0.0 3.1 2 2 0 2 2 2 2 PDZ domain DUF3337 PF11816.8 KFQ99536.1 - 8.3e-50 169.0 0.1 2.9e-49 167.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3337) WD40 PF00400.32 KFQ99536.1 - 1.9e-29 101.3 7.0 4.8e-05 24.1 0.1 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ99536.1 - 3.2e-07 30.6 2.9 0.036 14.4 0.2 4.1 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KFQ99536.1 - 0.009 14.8 0.6 0.74 8.5 0.4 3.2 1 1 1 2 2 2 1 Nup133 N terminal like WD40_like PF17005.5 KFQ99536.1 - 0.013 14.9 0.0 0.033 13.5 0.0 1.7 1 0 0 1 1 1 0 WD40-like domain RAWUL PF16207.5 KFQ99536.1 - 0.018 15.7 0.0 0.04 14.6 0.0 1.6 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like Nup160 PF11715.8 KFQ99536.1 - 0.17 10.5 8.5 2.1 6.9 0.9 4.0 2 1 2 4 4 4 0 Nucleoporin Nup120/160 Ion_trans PF00520.31 KFQ99538.1 - 9.6e-253 833.9 102.3 4.4e-79 265.2 15.3 4.1 4 0 0 4 4 4 4 Ion transport protein Na_trans_assoc PF06512.13 KFQ99538.1 - 2.2e-67 227.3 5.0 2.2e-67 227.3 5.0 1.9 2 0 0 2 2 2 1 Sodium ion transport-associated Na_trans_cytopl PF11933.8 KFQ99538.1 - 6.8e-53 179.6 1.3 1.6e-52 178.4 1.1 1.8 1 1 0 1 1 1 1 Cytoplasmic domain of voltage-gated Na+ ion channel PKD_channel PF08016.12 KFQ99538.1 - 1.1e-11 44.1 87.1 1.8e-06 26.9 2.7 9.9 6 4 3 9 9 9 8 Polycystin cation channel GPHH PF16905.5 KFQ99538.1 - 0.00025 20.8 0.0 0.00049 19.8 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated IQ PF00612.27 KFQ99538.1 - 0.0015 18.2 0.8 0.004 16.8 0.8 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif COX16 PF14138.6 KFQ99538.1 - 1.5 9.4 5.8 6.8 7.3 0.7 3.8 3 1 0 3 3 3 0 Cytochrome c oxidase assembly protein COX16 Endonuclease_NS PF01223.23 KFQ99539.1 - 1.6e-60 204.7 0.0 2.1e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Exog_C PF18026.1 KFQ99539.1 - 2e-27 94.9 0.8 4.2e-27 94.0 0.8 1.6 1 0 0 1 1 1 1 Endo/exonuclease (EXOG) C-terminal domain GA-like PF17573.2 KFQ99539.1 - 0.036 14.0 0.3 0.1 12.6 0.2 1.8 1 1 1 2 2 2 0 GA-like domain Pkinase PF00069.25 KFQ99540.1 - 4.2e-31 108.3 0.0 6.6e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ99540.1 - 6e-26 91.3 0.0 9.6e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Activin_recp PF01064.23 KFQ99540.1 - 2.3e-09 38.2 14.2 2.3e-09 38.2 14.2 1.9 2 0 0 2 2 2 1 Activin types I and II receptor domain Pkinase_fungal PF17667.1 KFQ99540.1 - 0.00085 18.2 0.0 0.0015 17.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Toxin_TOLIP PF00087.21 KFQ99540.1 - 5.5 7.3 14.4 0.63 10.3 9.9 1.8 2 0 0 2 2 2 0 Snake toxin and toxin-like protein FGGY_C PF02782.16 KFQ99543.1 - 2.2e-09 37.3 0.0 2.6e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KFQ99544.1 - 5.7e-17 62.1 0.0 9.1e-13 48.3 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KFQ99544.1 - 3.3e-06 27.0 0.0 1.3e-05 25.1 0.0 2.0 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4682 PF15733.5 KFQ99545.1 - 5e-23 82.1 0.2 7.6e-23 81.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4682) DUF3025 PF11227.8 KFQ99545.1 - 0.045 13.6 0.1 0.073 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) Ubiquitin_5 PF18037.1 KFQ99547.1 - 2.1e-34 117.8 1.2 7e-34 116.1 1.2 1.9 1 0 0 1 1 1 1 Ubiquitin-like domain UBA PF00627.31 KFQ99547.1 - 2.2e-27 94.5 0.0 1.2e-08 34.7 0.0 3.7 3 0 0 3 3 3 3 UBA/TS-N domain HOIP-UBA PF16678.5 KFQ99547.1 - 2.6e-05 24.3 11.4 0.00045 20.2 1.1 4.0 2 1 1 4 4 4 2 HOIP UBA domain pair UBA_4 PF14555.6 KFQ99547.1 - 0.00016 21.4 0.2 0.19 11.6 0.1 3.4 3 0 0 3 3 3 1 UBA-like domain TPR_12 PF13424.6 KFQ99547.1 - 0.00087 19.5 7.7 1.5 9.1 2.7 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat ubiquitin PF00240.23 KFQ99547.1 - 0.0016 18.1 1.6 0.0057 16.4 0.6 2.5 3 0 0 3 3 3 1 Ubiquitin family TPR_2 PF07719.17 KFQ99547.1 - 0.0035 17.4 10.4 0.087 13.0 0.9 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ99547.1 - 0.01 16.0 2.8 5.8 7.4 0.3 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat RuvA_C PF07499.13 KFQ99547.1 - 0.022 15.2 0.0 26 5.4 0.0 3.7 3 0 0 3 3 3 0 RuvA, C-terminal domain Rap1_C PF11626.8 KFQ99547.1 - 0.14 12.3 0.8 12 6.1 0.0 3.6 4 0 0 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain TPR_14 PF13428.6 KFQ99547.1 - 0.19 12.6 1.3 39 5.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFQ99547.1 - 0.67 9.9 6.2 6.3 6.8 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat HTH_8 PF02954.19 KFQ99547.1 - 0.72 9.7 4.3 8.7 6.2 0.2 3.3 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family Ras PF00071.22 KFQ99548.1 - 5.3e-43 146.4 0.4 6.2e-43 146.2 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ99548.1 - 1.9e-13 50.7 0.0 3.8e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ99548.1 - 8e-05 22.2 0.1 8.5e-05 22.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFQ99548.1 - 0.00015 21.4 0.1 0.00019 21.1 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFQ99548.1 - 0.0025 17.8 0.1 0.0043 17.0 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase CBS PF00571.28 KFQ99549.1 - 8.6e-33 112.6 3.3 2.6e-09 37.4 0.5 4.3 4 0 0 4 4 4 4 CBS domain Cbl_N3 PF02762.14 KFQ99549.1 - 0.099 12.5 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain IF-2 PF11987.8 KFQ99549.1 - 0.12 12.5 0.4 0.22 11.7 0.4 1.3 1 0 0 1 1 1 0 Translation-initiation factor 2 Glycos_transf_2 PF00535.26 KFQ99550.1 - 4.7e-31 107.9 0.0 7.4e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFQ99550.1 - 3.1e-22 79.2 2.3 4.7e-22 78.6 2.3 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 KFQ99550.1 - 7e-07 29.4 0.0 6.5e-06 26.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KFQ99550.1 - 7.6e-05 22.3 0.1 0.00019 21.0 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.6 KFQ99550.1 - 0.0008 20.1 0.2 2.6 8.9 0.0 2.5 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Glyco_tranf_2_2 PF10111.9 KFQ99550.1 - 0.04 13.4 0.0 0.075 12.5 0.0 1.5 1 1 0 1 1 1 0 Glycosyltransferase like family 2 PHD PF00628.29 KFQ99551.1 - 4.1e-36 122.6 142.3 8.5e-10 38.4 6.9 10.4 7 2 3 10 10 10 6 PHD-finger FYRC PF05965.14 KFQ99551.1 - 1.6e-25 89.0 0.0 9.2e-25 86.6 0.0 2.5 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 KFQ99551.1 - 1.3e-19 69.7 0.0 2.6e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus SET PF00856.28 KFQ99551.1 - 4e-18 66.4 0.3 4e-18 66.4 0.3 4.2 4 0 0 4 4 4 1 SET domain zf-HC5HC2H_2 PF13832.6 KFQ99551.1 - 2.8e-15 56.4 28.3 1.2e-10 41.6 9.2 9.2 3 2 5 8 8 8 3 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFQ99551.1 - 3.1e-15 56.2 27.4 1.4e-09 38.1 9.8 10.3 6 2 5 11 11 11 3 PHD-like zinc-binding domain HMG_box PF00505.19 KFQ99551.1 - 0.76 10.2 8.6 0.065 13.7 0.8 3.1 2 1 0 2 2 2 0 HMG (high mobility group) box Rad51 PF08423.11 KFQ99552.1 - 3e-19 69.3 0.0 3.5e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KFQ99552.1 - 0.0035 17.0 0.0 0.0052 16.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KFQ99552.1 - 0.0053 16.3 0.0 0.0091 15.5 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein NACHT PF05729.12 KFQ99552.1 - 0.059 13.3 0.7 0.71 9.8 0.7 2.2 1 1 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 KFQ99552.1 - 0.11 12.7 0.1 0.81 9.8 0.1 2.2 2 1 0 2 2 2 0 AAA domain Actin PF00022.19 KFQ99553.1 - 2.2e-86 290.0 0.0 1.2e-51 175.7 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 KFQ99553.1 - 2e-05 23.6 0.0 0.038 12.8 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 KFQ99553.1 - 0.0088 16.5 0.0 0.021 15.2 0.0 1.8 1 1 0 1 1 1 1 Cell division protein FtsA Robl_LC7 PF03259.17 KFQ99553.1 - 0.071 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Roadblock/LC7 domain DPPIV_N PF00930.21 KFQ99555.1 - 6.3e-111 370.5 0.2 9.2e-111 370.0 0.2 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KFQ99555.1 - 4.8e-37 127.5 0.1 9.2e-37 126.6 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 KFQ99555.1 - 1e-06 28.5 0.1 0.031 14.2 0.0 3.2 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat DLH PF01738.18 KFQ99555.1 - 9.1e-06 25.4 0.2 4.8e-05 23.0 0.2 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family PTCB-BRCT PF12738.7 KFQ99556.1 - 8e-55 182.7 3.0 7.4e-21 73.9 0.0 4.7 4 0 0 4 4 4 4 twin BRCT domain BRCT PF00533.26 KFQ99556.1 - 3.5e-50 168.3 2.3 2.9e-13 50.0 0.0 5.9 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KFQ99556.1 - 5.4e-31 106.9 0.8 2.2e-06 28.0 0.1 6.0 6 0 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KFQ99556.1 - 3e-25 88.0 5.5 2.3e-20 72.3 0.1 4.1 4 0 0 4 4 4 2 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 KFQ99556.1 - 3.9e-13 49.5 5.1 0.00012 22.3 0.0 5.7 5 1 0 5 5 5 3 DNA ligase 3 BRCT domain CENP-F_N PF10481.9 KFQ99557.1 - 0.23 11.1 2.2 0.24 11.0 2.2 1.0 1 0 0 1 1 1 0 Cenp-F N-terminal domain INSIG PF07281.12 KFQ99559.1 - 3.1e-37 128.3 4.5 3.4e-36 124.9 4.5 2.1 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) WH2 PF02205.20 KFQ99560.1 - 0.00015 21.5 1.1 0.0014 18.4 1.1 2.9 1 0 0 1 1 1 1 WH2 motif LRR_6 PF13516.6 KFQ99560.1 - 0.016 15.2 1.7 0.048 13.7 0.2 2.5 2 0 0 2 2 2 0 Leucine Rich repeat Tim17 PF02466.19 KFQ99561.1 - 2.6e-31 108.3 5.1 3.2e-31 108.0 5.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HlyIII PF03006.20 KFQ99562.1 - 2.4e-73 246.6 19.6 2.9e-73 246.3 19.6 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF4405 PF14358.6 KFQ99562.1 - 0.011 16.3 3.3 0.011 16.3 3.3 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4405) DUF962 PF06127.11 KFQ99562.1 - 1.4 9.1 9.1 0.051 13.7 1.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF962) FAD_binding_7 PF03441.14 KFQ99563.1 - 6.1e-80 267.5 2.2 9e-80 266.9 2.2 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KFQ99563.1 - 1.2e-20 74.2 0.0 4.7e-20 72.2 0.0 1.9 2 0 0 2 2 2 1 DNA photolyase DUF2189 PF09955.9 KFQ99592.1 - 0.022 15.0 3.7 0.025 14.8 3.7 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2189) Pellino PF04710.14 KFQ99593.1 - 1.9e-228 758.0 0.0 2.3e-228 757.8 0.0 1.0 1 0 0 1 1 1 1 Pellino Prok-RING_4 PF14447.6 KFQ99593.1 - 0.017 15.0 7.3 1.4 8.9 3.5 3.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFQ99593.1 - 0.091 12.6 10.2 1.5 8.8 0.6 3.5 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFQ99593.1 - 0.43 10.6 0.1 0.43 10.6 0.1 3.4 2 1 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 KFQ99593.1 - 0.7 10.3 10.8 0.67 10.3 0.2 3.1 3 0 0 3 3 3 0 Ring finger domain Vps54 PF07928.12 KFQ99594.1 - 2.9e-50 170.2 2.0 3.6e-49 166.6 1.0 3.0 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 KFQ99594.1 - 8.7e-08 31.8 7.4 8.7e-08 31.8 7.4 2.6 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 KFQ99594.1 - 0.15 12.2 4.2 14 5.8 0.0 3.4 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 UDPGP PF01704.18 KFQ99595.1 - 1.7e-198 659.3 0.2 2.1e-198 659.1 0.2 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Ldh_1_C PF02866.18 KFQ99596.1 - 1.8e-44 151.6 0.1 3.9e-44 150.5 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KFQ99596.1 - 4.4e-40 137.0 0.1 8.4e-40 136.1 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_3_C PF01915.22 KFQ99596.1 - 0.031 14.2 0.2 0.09 12.7 0.0 1.8 1 1 1 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain Frtz PF11768.8 KFQ99597.1 - 2.6e-231 768.7 0.1 3e-231 768.5 0.1 1.0 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz TF_Otx PF03529.13 KFQ99598.1 - 7.7e-36 122.4 18.2 7.7e-36 122.4 18.2 3.7 3 1 1 4 4 4 1 Otx1 transcription factor Homeodomain PF00046.29 KFQ99598.1 - 0.11 12.4 3.5 0.16 11.9 3.5 1.2 1 0 0 1 1 1 0 Homeodomain Sporozoite_P67 PF05642.11 KFQ99598.1 - 6.6 4.7 12.0 7.6 4.5 12.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NT-C2 PF10358.9 KFQ99599.1 - 4.3e-26 91.4 0.3 9e-26 90.3 0.3 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF3585 PF12130.8 KFQ99599.1 - 5.6e-23 81.6 11.1 5.6e-23 81.6 11.1 3.5 4 0 0 4 4 4 1 Bivalent Mical/EHBP Rab binding domain CH PF00307.31 KFQ99599.1 - 1e-21 77.1 0.0 2.7e-21 75.8 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFQ99599.1 - 0.00048 19.9 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 CAMSAP CH domain Isochorismatase PF00857.20 KFQ99599.1 - 0.12 12.5 0.8 0.32 11.1 0.2 2.0 2 0 0 2 2 2 0 Isochorismatase family DUF4287 PF14117.6 KFQ99599.1 - 0.19 11.9 0.1 0.38 10.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) Transmemb_17 PF09799.9 KFQ99600.1 - 2.1e-29 102.2 13.7 2.9e-29 101.8 13.7 1.2 1 0 0 1 1 1 1 Predicted membrane protein DUF3043 PF11241.8 KFQ99600.1 - 0.1 12.6 8.7 0.67 10.0 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3043) EGF_CA PF07645.15 KFQ99601.1 - 8.9e-08 32.2 8.0 1.6e-07 31.4 8.0 1.4 1 0 0 1 1 1 1 Calcium-binding EGF domain EGF_3 PF12947.7 KFQ99601.1 - 0.00056 20.0 4.3 0.0011 19.1 4.3 1.4 1 0 0 1 1 1 1 EGF domain Plasmod_Pvs28 PF06247.11 KFQ99601.1 - 0.0033 17.7 2.3 0.0051 17.1 2.3 1.3 1 0 0 1 1 1 1 Pvs28 EGF domain hEGF PF12661.7 KFQ99601.1 - 0.018 15.6 3.4 0.018 15.6 3.4 2.0 2 0 0 2 2 2 0 Human growth factor-like EGF FXa_inhibition PF14670.6 KFQ99601.1 - 0.023 15.0 3.3 0.064 13.5 3.5 1.7 1 1 0 1 1 1 0 Coagulation Factor Xa inhibitory site EGF PF00008.27 KFQ99601.1 - 0.88 9.9 9.1 0.18 12.1 5.3 1.9 3 0 0 3 3 3 0 EGF-like domain Galactosyl_T PF01762.21 KFQ99602.1 - 1.5e-42 145.6 0.0 2.5e-42 144.9 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 KFQ99602.1 - 0.0019 17.7 0.0 0.0031 17.0 0.0 1.2 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.12 KFQ99602.1 - 0.0063 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 COMMD1_N PF17221.3 KFQ99603.1 - 1.3e-43 147.5 0.1 2.3e-43 146.6 0.0 1.4 2 0 0 2 2 2 1 COMMD1 N-terminal domain COMM_domain PF07258.14 KFQ99603.1 - 1.6e-17 63.3 2.2 8.5e-17 61.1 1.7 2.1 2 1 0 2 2 2 1 COMM domain RVT_1 PF00078.27 KFQ99604.1 - 0.0015 18.1 0.0 0.0032 17.0 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDP-OH_P_transf PF01066.21 KFQ99605.1 - 1.1e-12 48.5 0.2 1.1e-12 48.5 0.2 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase MCM PF00493.23 KFQ99606.1 - 1.3e-87 292.6 0.0 1.8e-87 292.1 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 KFQ99606.1 - 3.6e-28 97.8 0.6 6.8e-28 96.9 0.6 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 KFQ99606.1 - 1.9e-24 85.9 1.3 3.6e-24 85.0 1.3 1.4 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 KFQ99606.1 - 3.1e-08 33.3 0.0 6e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFQ99606.1 - 1.4e-07 31.6 0.0 3.5e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFQ99606.1 - 0.00019 21.3 0.0 0.00048 20.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 KFQ99606.1 - 0.0075 16.7 0.0 0.023 15.1 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFQ99606.1 - 0.017 15.5 2.2 0.052 13.9 0.0 2.8 3 1 0 3 3 3 0 AAA ATPase domain NTPase_1 PF03266.15 KFQ99606.1 - 0.029 14.3 0.1 1.4 8.8 0.1 2.5 2 0 0 2 2 2 0 NTPase FtsK_SpoIIIE PF01580.18 KFQ99606.1 - 0.04 13.3 0.0 0.14 11.5 0.0 1.9 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.6 KFQ99606.1 - 0.062 13.6 0.0 0.22 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFQ99606.1 - 0.1 12.1 0.0 0.32 10.5 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Gcd10p PF04189.13 KFQ99607.1 - 6.9e-70 235.5 2.4 6.9e-70 235.5 2.4 1.9 1 1 1 2 2 2 1 Gcd10p family GAGA_bind PF06217.12 KFQ99607.1 - 1.8 8.8 8.7 8.8 6.5 3.6 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family Granin PF01271.17 KFQ99608.1 - 1.2e-51 176.4 116.6 1.4e-51 176.1 116.6 1.1 1 0 0 1 1 1 1 Granin (chromogranin or secretogranin) DUF4521 PF15021.6 KFQ99609.1 - 5.9e-83 277.8 0.4 7.3e-83 277.5 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4521) GDPD PF03009.17 KFQ99610.1 - 8.7e-62 209.2 0.1 1.4e-61 208.5 0.1 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CBM_20 PF00686.19 KFQ99610.1 - 9.6e-10 38.2 0.0 3.4e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Starch binding domain PI-PLC-X PF00388.19 KFQ99610.1 - 0.077 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain UPF0020 PF01170.18 KFQ99611.1 - 9e-26 90.8 0.0 5.5e-25 88.2 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 KFQ99611.1 - 2.6e-12 47.3 0.0 4.9e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFQ99611.1 - 5.5e-12 45.7 0.0 1.1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFQ99611.1 - 3.2e-10 40.5 0.0 9.9e-10 38.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFQ99611.1 - 2.7e-07 30.2 0.0 3.9e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KFQ99611.1 - 4.5e-07 29.6 0.0 7.4e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain THUMP PF02926.17 KFQ99611.1 - 9.8e-07 29.0 0.0 2.7e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 THUMP domain AviRa PF11599.8 KFQ99611.1 - 0.035 13.6 0.0 0.23 10.9 0.0 1.9 1 1 1 2 2 2 0 RRNA methyltransferase AviRa N6_Mtase PF02384.16 KFQ99611.1 - 0.099 11.9 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 N-6 DNA Methylase MSSP PF03940.13 KFQ99616.1 - 0.87 9.2 71.2 1.8e+04 -26.7 71.2 3.6 1 1 0 1 1 1 0 Male specific sperm protein Metallothi_Euk2 PF12809.7 KFQ99616.1 - 5 7.5 71.4 4.9 7.5 9.8 4.2 1 1 3 4 4 4 0 Eukaryotic metallothionein Cornifin PF02389.15 KFQ99617.1 - 0.026 14.7 65.1 2.2 8.5 65.1 2.2 1 1 0 1 1 1 0 Cornifin (SPRR) family Keratin PF02422.16 KFQ99619.1 - 2.3e-26 91.3 15.2 4e-26 90.5 15.2 1.5 1 1 0 1 1 1 1 Keratin TIL PF01826.17 KFQ99619.1 - 0.046 14.0 5.5 0.08 13.2 5.5 1.4 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Keratin PF02422.16 KFQ99620.1 - 2.3e-26 91.3 26.2 3.6e-26 90.7 15.7 2.2 1 1 1 2 2 2 1 Keratin DUF3432 PF11914.8 KFQ99620.1 - 0.36 11.1 10.9 0.21 11.8 9.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.16 KFQ99621.1 - 1.5e-31 107.9 11.4 1.5e-31 107.9 11.4 2.0 1 1 1 2 2 2 1 Keratin DUF3432 PF11914.8 KFQ99621.1 - 0.24 11.6 5.5 1.3 9.3 5.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.16 KFQ99622.1 - 9.3e-33 111.8 11.0 9.9e-33 111.7 11.0 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.8 KFQ99622.1 - 0.037 14.3 6.7 0.11 12.7 6.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3432) Keratin PF02422.16 KFQ99623.1 - 2.4e-28 97.7 10.2 2.6e-28 97.6 10.2 1.0 1 0 0 1 1 1 1 Keratin Cornifin PF02389.15 KFQ99623.1 - 0.0033 17.6 8.5 0.0034 17.6 8.5 1.0 1 0 0 1 1 1 1 Cornifin (SPRR) family DUF3432 PF11914.8 KFQ99623.1 - 0.03 14.6 0.9 0.034 14.4 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.16 KFQ99624.1 - 4.4e-32 109.6 9.7 4.7e-32 109.6 9.7 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.8 KFQ99624.1 - 0.077 13.3 4.9 0.12 12.6 4.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.16 KFQ99625.1 - 3e-30 103.8 6.7 3.2e-30 103.7 6.7 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.8 KFQ99625.1 - 0.18 12.1 3.5 0.22 11.8 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.16 KFQ99626.1 - 8.5e-37 124.7 13.9 9.3e-37 124.6 13.9 1.0 1 0 0 1 1 1 1 Keratin Fer4_3 PF12798.7 KFQ99626.1 - 7.3 7.8 8.5 4.8 8.4 1.3 2.9 3 0 0 3 3 3 0 4Fe-4S binding domain Keratin PF02422.16 KFQ99628.1 - 2.1e-36 123.5 8.5 1.5e-35 120.8 8.5 1.9 1 1 0 1 1 1 1 Keratin ASFV_J13L PF05568.11 KFQ99630.1 - 0.85 9.3 5.9 0.85 9.3 5.9 1.0 1 0 0 1 1 1 0 African swine fever virus J13L protein Keratin PF02422.16 KFQ99631.1 - 1.7e-40 136.6 6.4 1.7e-40 136.6 6.4 2.1 1 1 1 2 2 2 2 Keratin Keratin PF02422.16 KFQ99632.1 - 7e-40 134.6 3.1 7e-40 134.6 3.1 2.0 1 1 1 2 2 2 2 Keratin Keratin PF02422.16 KFQ99634.1 - 5.2e-32 109.4 10.5 5.6e-32 109.3 10.5 1.0 1 0 0 1 1 1 1 Keratin RNF111_N PF15303.6 KFQ99668.1 - 3.8e-44 151.5 31.8 5.2e-44 151.1 31.8 1.3 1 1 0 1 1 1 1 E3 ubiquitin-protein ligase Arkadia N-terminus MDMPI_C PF07398.11 KFQ99668.1 - 0.11 13.4 0.0 0.25 12.2 0.0 1.7 1 0 0 1 1 1 0 MDMPI C-terminal domain ATP-synt_ab PF00006.25 KFQ99669.1 - 2.8e-18 66.4 0.3 4.1e-18 65.8 0.3 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KFQ99669.1 - 3.4e-18 65.9 1.8 8.9e-18 64.6 1.8 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Lectin_C PF00059.21 KFQ99671.1 - 0.0019 18.9 0.0 0.0037 18.0 0.0 1.5 1 0 0 1 1 1 1 Lectin C-type domain Chordopox_A33R PF05966.12 KFQ99671.1 - 0.0024 17.2 0.1 0.0039 16.5 0.1 1.3 1 0 0 1 1 1 1 Chordopoxvirus A33R protein UL45 PF05473.12 KFQ99671.1 - 0.029 14.0 0.5 0.11 12.2 0.4 1.8 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like SIT PF15330.6 KFQ99671.1 - 6.7 7.2 5.8 2.2e+02 2.3 5.8 2.2 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT TED_complement PF07678.14 KFQ99672.1 - 1.4e-43 149.1 0.0 1.5e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 A-macroglobulin TED domain SQHop_cyclase_C PF13243.6 KFQ99672.1 - 0.022 13.9 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain TPP_enzyme_N PF02776.18 KFQ99676.1 - 4.2e-29 101.3 4.3 4.8e-29 101.2 4.3 1.0 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Adeno_PX PF05829.12 KFQ99676.1 - 0.38 10.6 4.1 0.96 9.4 4.1 1.7 1 0 0 1 1 1 0 Adenovirus late L2 mu core protein (Protein X) zf-H2C2_2 PF13465.6 KFQ99677.1 - 2.8e-16 59.1 7.4 4.5e-05 23.7 0.0 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ99677.1 - 4.6e-13 48.8 4.0 0.00029 21.1 0.2 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ99677.1 - 1.7e-09 37.7 6.8 0.0056 17.4 0.0 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf_UBZ PF18439.1 KFQ99677.1 - 3.1e-06 26.7 2.8 0.37 10.4 0.1 3.2 3 0 0 3 3 3 3 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 KFQ99677.1 - 2.1e-05 24.4 9.8 1 9.4 0.1 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFQ99677.1 - 3.6e-05 23.8 6.7 0.0051 16.9 3.6 2.2 1 1 1 2 2 2 2 Zinc ribbon domain XPA_N PF01286.18 KFQ99677.1 - 0.00042 20.3 5.5 0.64 10.1 0.1 3.1 3 0 0 3 3 3 2 XPA protein N-terminal zf-LYAR PF08790.11 KFQ99677.1 - 0.00082 19.2 0.7 2.1 8.3 0.1 3.2 3 0 0 3 3 3 1 LYAR-type C2HC zinc finger zf_C2H2_ZHX PF18387.1 KFQ99677.1 - 0.0021 17.6 5.1 0.23 11.1 0.1 2.3 1 1 1 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain TFIIS_C PF01096.18 KFQ99677.1 - 0.0024 17.7 4.8 1.8 8.5 0.1 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) YhfH PF14149.6 KFQ99677.1 - 0.004 17.1 6.1 5 7.2 0.1 3.1 3 0 0 3 3 3 0 YhfH-like protein CpXC PF14353.6 KFQ99677.1 - 0.0043 17.1 4.9 1.5 8.8 0.0 3.0 2 1 1 3 3 3 1 CpXC protein zf-C2H2_8 PF15909.5 KFQ99677.1 - 0.0049 17.1 0.1 0.0054 17.0 0.1 1.1 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 KFQ99677.1 - 0.0062 16.3 6.3 0.58 10.0 0.5 3.0 3 0 0 3 3 3 1 zinc-finger C2H2-type RNA_POL_M_15KD PF02150.16 KFQ99677.1 - 0.0077 16.1 4.6 0.46 10.4 0.0 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit zf-trcl PF13451.6 KFQ99677.1 - 0.0087 15.9 4.0 4.4 7.3 0.1 3.0 3 0 0 3 3 3 0 Probable zinc-ribbon domain zf-UBP PF02148.19 KFQ99677.1 - 0.011 16.0 4.6 1.3 9.4 4.5 2.7 1 1 2 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein HypA PF01155.19 KFQ99677.1 - 0.015 15.3 2.7 0.051 13.6 0.3 2.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KFQ99677.1 - 0.026 14.5 10.0 0.18 11.8 10.2 1.9 1 1 1 2 2 2 0 Double zinc ribbon zf-AN1 PF01428.16 KFQ99677.1 - 0.028 14.6 9.1 4.4 7.6 0.8 3.2 2 1 1 3 3 3 0 AN1-like Zinc finger zinc_ribbon_9 PF14369.6 KFQ99677.1 - 0.033 14.5 8.5 2.6 8.4 0.4 3.1 3 0 0 3 3 3 0 zinc-ribbon FYDLN_acid PF09538.10 KFQ99677.1 - 0.044 14.5 3.6 12 6.7 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) FYVE PF01363.21 KFQ99677.1 - 0.044 13.9 3.9 1.9 8.7 3.9 2.2 1 1 0 1 1 1 0 FYVE zinc finger C1_4 PF07975.12 KFQ99677.1 - 0.046 14.0 0.7 13 6.1 0.6 2.3 1 1 0 2 2 2 0 TFIIH C1-like domain LIM PF00412.22 KFQ99677.1 - 0.062 13.5 5.0 0.43 10.8 1.2 2.6 2 1 0 2 2 2 0 LIM domain CxC7 PF18866.1 KFQ99677.1 - 0.074 13.2 4.3 2.3 8.4 0.2 2.9 2 1 1 3 3 3 0 CxC7 like cysteine cluster associated with KDZ transposases zf-C2H2_3rep PF18868.1 KFQ99677.1 - 0.094 13.4 3.0 0.28 11.9 1.1 2.0 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-HYPF PF07503.12 KFQ99677.1 - 0.15 11.9 7.2 2.7 7.8 0.1 3.1 3 0 0 3 3 3 0 HypF finger zf-ribbon_3 PF13248.6 KFQ99677.1 - 0.17 11.4 9.8 2.8 7.5 1.0 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Zn_ribbon_recom PF13408.6 KFQ99677.1 - 0.2 12.2 7.1 12 6.4 3.4 2.8 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain DNA_RNApol_7kD PF03604.13 KFQ99677.1 - 0.22 11.2 7.5 2.5 7.9 0.1 3.0 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_4 PF13717.6 KFQ99677.1 - 0.54 10.2 9.4 14 5.7 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-MYND PF01753.18 KFQ99677.1 - 0.58 10.3 7.2 51 4.1 7.2 2.7 1 1 0 1 1 1 0 MYND finger DUF2256 PF10013.9 KFQ99677.1 - 0.66 10.1 6.1 29 4.9 0.3 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HE PF16278.5 KFQ99677.1 - 0.67 10.4 6.2 5.2 7.6 0.3 2.9 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-ISL3 PF14690.6 KFQ99677.1 - 0.78 10.5 11.8 10 6.9 0.3 3.1 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 PADR1 PF08063.12 KFQ99677.1 - 0.85 9.5 5.4 1.9 8.3 0.5 2.8 3 0 0 3 3 3 0 PADR1 (NUC008) domain zf-tcix PF14952.6 KFQ99677.1 - 0.85 9.3 7.7 20 4.9 0.1 3.1 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding NinF PF05810.12 KFQ99677.1 - 0.92 9.4 4.0 7.5 6.5 0.1 2.6 3 0 0 3 3 3 0 NinF protein HscB_4_cys PF18256.1 KFQ99677.1 - 1.1 9.1 14.5 1.5 8.7 1.6 3.2 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif zf-RRN7 PF11781.8 KFQ99677.1 - 3.5 7.4 9.9 19 5.1 0.8 3.2 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 RNHCP PF12647.7 KFQ99677.1 - 3.6 7.6 6.5 57 3.8 4.0 2.7 2 1 0 2 2 2 0 RNHCP domain DUF1610 PF07754.11 KFQ99677.1 - 3.7 7.6 15.5 0.47 10.5 1.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) zinc_ribbon_2 PF13240.6 KFQ99677.1 - 4.8 7.0 12.2 5.2 6.9 1.0 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Ribosomal_L37ae PF01780.19 KFQ99677.1 - 7.5 6.7 7.7 4.4 7.5 0.4 2.8 1 1 2 3 3 3 0 Ribosomal L37ae protein family cNMP_binding PF00027.29 KFQ99678.1 - 2.4e-52 175.0 0.1 7.6e-16 58.0 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Patatin PF01734.22 KFQ99678.1 - 1.3e-21 77.8 0.1 2.8e-21 76.6 0.1 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase PKD_channel PF08016.12 KFQ99679.1 - 3.2e-10 39.3 16.7 4.4e-10 38.8 16.7 1.3 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KFQ99679.1 - 0.0057 15.9 27.4 0.011 14.9 27.5 1.4 1 1 0 1 1 1 1 Ion transport protein DUF373 PF04123.13 KFQ99679.1 - 4.7 6.6 10.5 0.85 9.0 4.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF373) p450 PF00067.22 KFQ99680.1 - 5.5e-108 361.7 0.0 1.2e-97 327.6 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 TetR_C_28 PF17937.1 KFQ99680.1 - 0.0067 16.9 4.6 1.7 9.1 0.0 3.5 3 0 0 3 3 3 2 Tetracyclin repressor-like, C-terminal domain MPC PF03650.13 KFQ99687.1 - 3.6e-37 126.9 0.9 3.8e-37 126.8 0.9 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers V-set PF07686.17 KFQ99688.1 - 1.3e-21 76.8 0.0 1.9e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFQ99688.1 - 1.5e-07 31.5 0.0 6.4e-07 29.5 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFQ99688.1 - 1.5e-05 25.5 0.6 7.8e-05 23.2 0.1 2.4 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFQ99688.1 - 8.7e-05 22.5 0.1 0.00036 20.5 0.1 1.9 1 1 0 1 1 1 1 Immunoglobulin I-set domain Myelin-PO_C PF10570.9 KFQ99688.1 - 0.038 14.4 0.0 0.094 13.2 0.0 1.6 1 0 0 1 1 1 0 Myelin-PO cytoplasmic C-term p65 binding region Ig_2 PF13895.6 KFQ99688.1 - 0.075 13.4 0.1 0.8 10.1 0.1 2.2 1 1 0 1 1 1 0 Immunoglobulin domain Pyrid_oxidase_2 PF13883.6 KFQ99689.1 - 6.2e-57 192.3 0.0 7e-57 192.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase TCR_zetazeta PF11628.8 KFQ99690.1 - 4.3e-17 61.5 0.4 6.3e-17 61.0 0.4 1.3 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 zeta chain ITAM PF02189.15 KFQ99690.1 - 1.4e-15 56.7 3.5 7e-06 26.2 0.1 3.4 3 0 0 3 3 3 3 Immunoreceptor tyrosine-based activation motif Pou PF00157.17 KFQ99691.1 - 2.9e-38 129.7 0.2 7e-38 128.4 0.2 1.7 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KFQ99691.1 - 1.4e-17 63.2 2.7 3.7e-17 61.9 2.7 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFQ99691.1 - 0.065 13.2 0.1 0.18 11.7 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain HTH_31 PF13560.6 KFQ99691.1 - 0.09 13.1 1.2 1.4 9.3 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain DSPc PF00782.20 KFQ99692.1 - 2.3e-26 92.2 0.0 6e-26 90.8 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain ig PF00047.25 KFQ99693.1 - 3.8e-15 55.8 2.0 8e-08 32.4 0.6 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 KFQ99693.1 - 4.3e-14 52.9 1.6 7.2e-09 36.1 0.3 2.2 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFQ99693.1 - 1.1e-13 51.3 2.0 7.4e-09 35.8 0.0 3.1 2 1 1 3 3 3 3 Immunoglobulin V-set domain I-set PF07679.16 KFQ99693.1 - 2.1e-13 50.1 0.2 1.6e-07 31.3 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFQ99693.1 - 7.8e-13 48.6 1.4 4.5e-07 30.1 0.5 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFQ99693.1 - 3.3e-06 27.1 0.0 0.022 14.8 0.0 2.1 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFQ99693.1 - 3.3e-06 27.4 0.0 0.0017 18.7 0.1 2.3 2 0 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFQ99693.1 - 8.7e-05 22.7 0.1 0.051 13.8 0.1 2.3 2 0 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFQ99693.1 - 0.00058 19.4 5.8 0.19 11.3 0.0 2.7 3 0 0 3 3 2 2 Immunoglobulin domain Adeno_E3_CR1 PF02440.15 KFQ99693.1 - 0.00063 19.5 0.2 0.037 13.8 0.1 2.3 2 0 0 2 2 2 1 Adenovirus E3 region protein CR1 C2-set_2 PF08205.12 KFQ99693.1 - 0.002 18.1 0.4 0.0039 17.2 0.2 1.6 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain BppU_N PF10651.9 KFQ99693.1 - 0.0077 15.9 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 BppU N-terminal domain Herpes_gE PF02480.16 KFQ99693.1 - 0.0085 14.9 3.1 4.6 5.9 0.0 2.9 1 1 2 3 3 3 2 Alphaherpesvirus glycoprotein E stn_TNFRSF12A PF12191.8 KFQ99693.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF1735 PF08522.10 KFQ99693.1 - 0.12 13.0 0.0 0.29 11.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1735) LSR PF05624.14 KFQ99694.1 - 1.5e-24 85.7 33.5 2.3e-24 85.1 33.5 1.3 1 0 0 1 1 1 1 Lipolysis stimulated receptor (LSR) V-set PF07686.17 KFQ99694.1 - 6e-06 26.4 0.1 0.0041 17.3 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin V-set domain zf-H2C2_2 PF13465.6 KFQ99695.1 - 7.2e-56 184.3 45.4 5.5e-09 36.0 1.1 9.1 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFQ99695.1 - 2e-48 160.2 59.1 1.1e-07 32.0 0.6 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFQ99695.1 - 1.6e-32 109.4 55.0 0.00027 21.5 2.7 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ99695.1 - 1.5e-12 47.4 20.8 0.11 12.8 0.3 7.8 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFQ99695.1 - 4.8e-12 45.2 30.9 0.044 13.4 0.1 8.2 8 0 0 8 8 8 3 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFQ99695.1 - 2.3e-11 43.6 33.1 0.00076 19.5 3.6 6.4 4 2 3 7 7 7 5 Zinc ribbon domain zf-C2H2_6 PF13912.6 KFQ99695.1 - 2.5e-09 36.9 55.5 0.17 11.9 0.5 9.1 8 2 0 8 8 8 6 C2H2-type zinc finger XPA_N PF01286.18 KFQ99695.1 - 1.8e-08 34.3 28.2 0.33 11.0 0.4 8.0 8 0 0 8 8 8 3 XPA protein N-terminal DZR PF12773.7 KFQ99695.1 - 1.8e-07 31.1 31.7 1.8e+04 -8.8 31.7 5.3 1 1 0 1 1 0 0 Double zinc ribbon C1_1 PF00130.22 KFQ99695.1 - 3e-07 30.2 29.0 0.071 13.0 0.7 6.7 1 1 6 7 7 7 4 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_15 PF17032.5 KFQ99695.1 - 5.1e-07 30.4 22.5 0.11 13.2 0.4 4.7 1 1 4 5 5 5 5 zinc-ribbon family DNA_RNApol_7kD PF03604.13 KFQ99695.1 - 1.2e-05 24.8 28.9 1.2 8.9 0.2 8.1 8 0 0 8 8 8 1 DNA directed RNA polymerase, 7 kDa subunit FYDLN_acid PF09538.10 KFQ99695.1 - 6.4e-05 23.6 15.8 5.6 7.7 0.8 7.3 1 1 6 7 7 7 0 Protein of unknown function (FYDLN_acid) ADK_lid PF05191.14 KFQ99695.1 - 9.8e-05 22.3 21.9 1.4 9.0 0.3 6.2 2 2 4 6 6 6 3 Adenylate kinase, active site lid zf-trcl PF13451.6 KFQ99695.1 - 0.00018 21.4 22.4 5.6 6.9 0.1 7.8 8 0 0 8 8 8 0 Probable zinc-ribbon domain CpXC PF14353.6 KFQ99695.1 - 0.00057 19.9 25.3 0.99 9.5 0.2 7.4 2 2 4 7 7 7 2 CpXC protein zf-LYAR PF08790.11 KFQ99695.1 - 0.0011 18.8 31.8 0.9 9.5 0.1 8.2 8 0 0 8 8 8 1 LYAR-type C2HC zinc finger YhfH PF14149.6 KFQ99695.1 - 0.0017 18.3 29.9 4 7.5 0.1 8.0 8 0 0 8 8 8 1 YhfH-like protein zf-AN1 PF01428.16 KFQ99695.1 - 0.0018 18.4 40.4 2 8.6 4.4 8.2 5 2 3 8 8 8 1 AN1-like Zinc finger zf-Di19 PF05605.12 KFQ99695.1 - 0.0035 17.6 4.8 0.023 15.0 1.6 5.5 1 1 5 7 7 7 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 KFQ99695.1 - 0.0039 16.9 2.9 0.044 13.5 0.2 8.0 8 0 0 8 8 8 3 zinc-finger C2H2-type HypA PF01155.19 KFQ99695.1 - 0.0057 16.7 21.8 1.5 8.8 1.1 4.7 1 1 4 5 5 5 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_SprT PF17283.2 KFQ99695.1 - 0.011 15.6 34.4 0.028 14.3 4.0 6.3 5 2 1 6 6 6 0 SprT-like zinc ribbon domain DUF3268 PF11672.8 KFQ99695.1 - 0.02 15.2 20.3 1.5 9.2 0.7 4.6 1 1 6 7 7 7 0 zinc-finger-containing domain C1_4 PF07975.12 KFQ99695.1 - 0.042 14.1 27.7 0.7 10.2 1.1 5.5 1 1 6 7 7 7 0 TFIIH C1-like domain LIM PF00412.22 KFQ99695.1 - 0.063 13.5 29.1 2.5 8.4 0.8 6.0 1 1 6 7 7 7 0 LIM domain TFIIS_C PF01096.18 KFQ99695.1 - 0.087 12.7 31.4 8.1 6.4 0.2 7.7 6 2 1 7 7 7 0 Transcription factor S-II (TFIIS) zf-C2HE PF16278.5 KFQ99695.1 - 0.093 13.2 37.6 1 9.8 1.1 7.8 1 1 6 8 8 8 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 KFQ99695.1 - 0.13 12.7 45.9 0.12 12.8 1.8 7.6 8 0 0 8 8 7 0 Zinc-finger of C2H2 type HTH_18 PF12833.7 KFQ99695.1 - 0.14 12.5 0.7 3.3e+02 1.6 0.0 4.7 5 1 1 6 6 5 0 Helix-turn-helix domain OSTMP1 PF09777.9 KFQ99695.1 - 0.18 11.2 8.0 0.43 9.9 6.7 2.1 1 1 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor zinc_ribbon_9 PF14369.6 KFQ99695.1 - 0.2 11.9 31.1 8.4 6.7 0.3 7.7 7 1 1 8 8 8 0 zinc-ribbon Zn_Tnp_IS1595 PF12760.7 KFQ99695.1 - 0.26 11.3 36.7 1.1 9.3 4.6 6.0 4 1 1 5 5 5 0 Transposase zinc-ribbon domain Zn_ribbon_recom PF13408.6 KFQ99695.1 - 0.39 11.3 37.0 3.9 8.0 2.1 6.6 2 1 3 6 6 6 0 Recombinase zinc beta ribbon domain zinc-ribbons_6 PF07191.12 KFQ99695.1 - 0.52 10.3 29.8 89 3.2 7.7 6.2 1 1 2 3 3 2 0 zinc-ribbons Zn-C2H2_12 PF18112.1 KFQ99695.1 - 0.57 10.7 0.1 0.57 10.7 0.1 5.1 7 0 0 7 7 3 0 Autophagy receptor zinc finger-C2H2 domain PknG_rubred PF16919.5 KFQ99695.1 - 0.78 9.9 32.8 0.19 11.9 2.7 5.1 1 1 3 5 5 5 0 Protein kinase G rubredoxin domain zf-HIT PF04438.16 KFQ99695.1 - 0.8 9.6 36.4 2.8 7.9 0.4 7.8 8 0 0 8 8 8 0 HIT zinc finger DUF2256 PF10013.9 KFQ99695.1 - 0.86 9.8 21.1 29 4.9 0.1 7.3 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) BolA PF01722.18 KFQ99695.1 - 1.2 9.5 7.8 31 4.9 0.2 3.8 2 2 1 3 3 3 0 BolA-like protein Yippee-Mis18 PF03226.14 KFQ99695.1 - 1.3 9.3 24.2 1.5e+02 2.7 4.4 5.7 2 2 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Rpr2 PF04032.16 KFQ99695.1 - 2.6 8.4 26.5 2e+02 2.4 4.0 4.6 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF2072 PF09845.9 KFQ99695.1 - 3.5 7.9 29.3 8.7 6.6 4.4 7.0 7 1 0 7 7 7 0 Zn-ribbon containing protein zinc_ribbon_4 PF13717.6 KFQ99695.1 - 5.7 7.0 31.6 4.4 7.3 0.1 7.3 5 2 2 7 7 7 0 zinc-ribbon domain HalOD2 PF18547.1 KFQ99695.1 - 7.5 6.5 31.0 4.9 7.1 3.3 6.5 4 2 2 6 6 6 0 Halobacterial output domain 2 Ig_3 PF13927.6 KFQ99697.1 - 0.00013 22.5 0.3 0.51 11.0 0.0 3.1 2 2 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFQ99697.1 - 0.00086 19.3 0.0 0.47 10.6 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFQ99697.1 - 0.026 14.8 0.2 0.68 10.3 0.1 2.9 1 1 2 3 3 3 0 Immunoglobulin domain Orthoreo_P10 PF07204.11 KFQ99697.1 - 0.057 13.4 2.1 0.064 13.2 0.2 2.0 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 ig PF00047.25 KFQ99697.1 - 0.061 13.5 2.9 13 6.1 0.2 3.3 3 1 0 3 3 3 0 Immunoglobulin domain I-set PF07679.16 KFQ99698.1 - 0.00093 19.2 0.9 0.0011 19.0 0.1 1.6 2 0 0 2 2 2 1 Immunoglobulin I-set domain V-set PF07686.17 KFQ99698.1 - 0.01 16.0 0.7 0.029 14.5 0.1 2.0 1 1 1 2 2 2 0 Immunoglobulin V-set domain Ig_3 PF13927.6 KFQ99698.1 - 0.035 14.7 1.8 0.047 14.3 0.1 2.1 2 1 1 3 3 3 0 Immunoglobulin domain V-set PF07686.17 KFQ99699.1 - 5.5e-30 103.7 11.7 8e-07 29.2 0.1 6.2 6 0 0 6 6 6 5 Immunoglobulin V-set domain Ig_3 PF13927.6 KFQ99699.1 - 1.3e-29 102.6 9.3 1.8e-06 28.4 0.0 6.9 6 1 0 6 6 6 5 Immunoglobulin domain I-set PF07679.16 KFQ99699.1 - 4.6e-20 71.5 5.6 8.9e-05 22.5 0.0 8.2 7 2 1 8 8 8 5 Immunoglobulin I-set domain ig PF00047.25 KFQ99699.1 - 8.3e-16 57.9 15.8 0.00021 21.4 0.0 7.8 6 4 0 6 6 6 4 Immunoglobulin domain Ig_2 PF13895.6 KFQ99699.1 - 4.2e-13 49.4 16.9 0.005 17.1 0.1 8.6 5 5 0 5 5 5 4 Immunoglobulin domain Izumo-Ig PF16706.5 KFQ99699.1 - 4.1e-05 23.5 0.4 1.5 9.0 0.0 5.3 6 0 0 6 6 6 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFQ99699.1 - 0.00034 20.1 0.2 5.5 6.6 0.0 4.7 5 0 0 5 5 5 1 Immunoglobulin domain Ig_5 PF16681.5 KFQ99699.1 - 0.021 15.2 0.3 11 6.6 0.0 4.5 4 1 0 4 4 4 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set PF07686.17 KFQ99700.1 - 2.2e-64 214.4 1.8 3.7e-15 56.0 0.0 7.2 7 0 0 7 7 7 7 Immunoglobulin V-set domain Ig_3 PF13927.6 KFQ99700.1 - 6.7e-51 170.8 1.8 3.7e-07 30.7 0.0 8.3 7 2 0 7 7 7 7 Immunoglobulin domain I-set PF07679.16 KFQ99700.1 - 7.2e-37 125.4 1.4 5e-06 26.5 0.0 10.8 7 5 0 7 7 7 7 Immunoglobulin I-set domain ig PF00047.25 KFQ99700.1 - 2e-26 91.9 5.5 2.3e-05 24.5 0.0 9.5 8 3 0 8 8 8 5 Immunoglobulin domain Ig_2 PF13895.6 KFQ99700.1 - 4.6e-24 84.6 7.5 0.0048 17.2 0.0 11.5 8 6 0 8 8 8 5 Immunoglobulin domain Izumo-Ig PF16706.5 KFQ99700.1 - 4e-08 33.2 0.3 0.42 10.7 0.0 6.6 8 0 0 8 8 8 2 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFQ99700.1 - 2.2e-06 27.1 0.0 15 5.3 0.0 5.4 5 0 0 5 5 5 2 Immunoglobulin domain Ig_4 PF16680.5 KFQ99700.1 - 0.0019 18.4 0.4 6.5 7.1 0.0 5.1 6 0 0 6 6 6 1 T-cell surface glycoprotein CD3 delta chain Transglut_N PF00868.20 KFQ99700.1 - 0.024 15.0 0.1 0.39 11.1 0.0 2.8 3 0 0 3 3 3 0 Transglutaminase family C2-set PF05790.15 KFQ99700.1 - 0.096 12.9 1.7 22 5.3 0.0 4.1 4 0 0 4 4 4 0 Immunoglobulin C2-set domain V-set PF07686.17 KFQ99701.1 - 2.4e-69 230.4 7.8 6.2e-11 42.4 0.0 8.6 8 0 0 8 8 8 8 Immunoglobulin V-set domain Ig_3 PF13927.6 KFQ99701.1 - 4.9e-54 180.9 7.4 1.5e-06 28.7 0.0 9.4 8 1 0 8 8 8 8 Immunoglobulin domain I-set PF07679.16 KFQ99701.1 - 2.3e-40 136.6 5.4 8.3e-05 22.6 0.0 11.2 8 4 0 8 8 8 8 Immunoglobulin I-set domain ig PF00047.25 KFQ99701.1 - 6.8e-34 115.9 9.2 0.00064 19.8 0.0 9.7 8 3 0 8 8 8 8 Immunoglobulin domain Ig_2 PF13895.6 KFQ99701.1 - 2.7e-18 66.1 24.4 0.14 12.5 0.2 13.3 9 7 0 9 9 9 5 Immunoglobulin domain Ig_6 PF18452.1 KFQ99701.1 - 1.3e-09 37.4 0.0 2 8.0 0.0 7.1 7 0 0 7 7 7 2 Immunoglobulin domain DUF3821 PF12863.7 KFQ99701.1 - 1.8e-06 28.0 0.1 0.32 10.9 0.0 4.4 4 0 0 4 4 4 2 Domain of unknown function (DUF3821) C2-set PF05790.15 KFQ99701.1 - 0.002 18.3 0.5 8.3 6.7 0.0 5.1 4 0 0 4 4 4 1 Immunoglobulin C2-set domain Herpes_gI PF01688.17 KFQ99701.1 - 0.012 15.5 0.0 8.1 6.3 0.0 3.6 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein I ADP_ribosyl_GH PF03747.14 KFQ99702.1 - 1.6e-54 185.6 1.0 1.8e-54 185.4 1.0 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase V-set PF07686.17 KFQ99703.1 - 5.8e-10 39.3 1.3 6.9e-10 39.1 0.4 1.5 2 0 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFQ99703.1 - 8.2e-09 35.4 2.8 1.4e-08 34.7 0.4 2.1 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 KFQ99703.1 - 1.3e-06 28.9 5.5 0.00062 20.3 0.1 3.1 2 1 1 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFQ99703.1 - 3.7e-06 27.0 1.3 9.2e-05 22.5 0.3 2.7 2 1 0 2 2 2 1 Immunoglobulin domain Ig_6 PF18452.1 KFQ99703.1 - 3.9e-05 23.1 0.0 7.9e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ99703.1 - 0.00018 21.5 1.0 0.00064 19.7 0.1 2.4 2 2 1 3 3 3 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFQ99703.1 - 0.0011 19.2 6.7 0.13 12.6 0.3 2.9 2 2 1 3 3 3 2 Immunoglobulin domain SPT_ssu-like PF11779.8 KFQ99703.1 - 0.0017 17.9 0.1 0.0044 16.6 0.1 1.7 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Tim17 PF02466.19 KFQ99705.1 - 9.7e-12 45.3 5.7 1.3e-11 44.8 5.7 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PilJ PF13675.6 KFQ99705.1 - 0.035 14.1 0.6 0.051 13.6 0.6 1.3 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term BCL9 PF11502.8 KFQ99706.1 - 1.6e-20 72.6 2.0 6.1e-20 70.7 2.0 2.1 1 0 0 1 1 1 1 B-cell lymphoma 9 protein His_Phos_2 PF00328.22 KFQ99707.1 - 9.7e-21 74.5 0.0 8.7e-20 71.4 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Connexin PF00029.19 KFQ99708.1 - 1.6e-99 332.4 2.8 2e-99 332.1 2.8 1.1 1 0 0 1 1 1 1 Connexin Connexin40_C PF16791.5 KFQ99708.1 - 4.2e-24 85.9 1.7 4.2e-24 85.9 1.7 1.8 3 0 0 3 3 3 1 Connexin 40 C-terminal domain Connexin PF00029.19 KFQ99709.1 - 6.2e-101 337.0 0.1 6.2e-101 337.0 0.1 1.8 2 0 0 2 2 2 1 Connexin Connexin50 PF03509.14 KFQ99709.1 - 2.1e-28 98.9 0.7 2.1e-28 98.9 0.7 2.4 2 0 0 2 2 2 1 Gap junction alpha-8 protein (Cx50) Connexin40_C PF16791.5 KFQ99709.1 - 4.6e-05 24.6 0.0 9.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Connexin 40 C-terminal domain ABA_GPCR PF12430.8 KFQ99710.1 - 5.1e-42 143.7 12.4 5.1e-42 143.7 12.4 2.2 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KFQ99710.1 - 7.9e-29 99.5 0.4 2.1e-28 98.2 0.1 1.9 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal NPCC PF08058.11 KFQ99710.1 - 0.68 10.0 0.0 0.68 10.0 0.0 3.4 3 1 0 3 3 3 0 Nuclear pore complex component DUF1772 PF08592.11 KFQ99710.1 - 8.6 6.7 7.0 10 6.4 0.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) PDZ PF00595.24 KFQ99711.1 - 4.1e-54 180.9 11.6 2e-13 50.5 0.1 4.4 5 0 0 5 5 5 4 PDZ domain PDZ_6 PF17820.1 KFQ99711.1 - 2.5e-49 164.9 9.1 1.2e-12 47.4 0.5 4.2 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 KFQ99711.1 - 1.5e-32 111.7 9.5 1.5e-08 34.8 0.2 4.2 4 0 0 4 4 4 4 PDZ domain GRASP55_65 PF04495.14 KFQ99711.1 - 4.9e-10 39.9 2.0 0.022 15.1 0.1 4.1 3 1 1 4 4 4 3 GRASP55/65 PDZ-like domain Tricorn_PDZ PF14685.6 KFQ99711.1 - 7.8e-07 29.0 4.8 0.022 14.7 0.1 4.4 4 0 0 4 4 4 2 Tricorn protease PDZ domain DUF3394 PF11874.8 KFQ99711.1 - 0.00045 20.0 0.3 3.9 7.1 0.1 4.0 3 2 1 4 4 4 2 Domain of unknown function (DUF3394) DUF4265 PF14085.6 KFQ99711.1 - 0.011 15.7 0.9 0.022 14.7 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) DUF5354 PF17305.2 KFQ99711.1 - 0.14 12.4 3.6 0.45 10.7 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5354) DUF1450 PF07293.11 KFQ99711.1 - 6.3 6.7 7.5 8.3 6.3 0.2 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1450) 7tm_1 PF00001.21 KFQ99712.1 - 1.5e-75 253.9 11.0 2.2e-75 253.4 11.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ99712.1 - 3.3e-07 29.9 17.2 1.8e-06 27.6 17.2 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFQ99712.1 - 6.9e-05 22.6 14.6 6.9e-05 22.6 14.6 2.2 2 2 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx Pou PF00157.17 KFQ99714.1 - 1.2e-34 118.1 3.3 7.9e-34 115.5 0.4 3.0 3 0 0 3 3 3 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KFQ99714.1 - 1e-17 63.7 2.1 1e-17 63.7 2.1 1.8 2 0 0 2 2 2 1 Homeodomain HTH_31 PF13560.6 KFQ99714.1 - 0.06 13.7 0.0 4.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Homeobox_KN PF05920.11 KFQ99714.1 - 0.16 11.9 0.0 0.42 10.6 0.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain Lsr2 PF11774.8 KFQ99714.1 - 0.16 12.1 0.2 0.32 11.1 0.2 1.5 1 0 0 1 1 1 0 Lsr2 Snf7 PF03357.21 KFQ99715.1 - 1.3e-43 148.5 29.1 1.3e-43 148.5 29.1 1.4 2 0 0 2 2 2 1 Snf7 DnaJ-X PF14308.6 KFQ99715.1 - 0.00024 20.6 13.5 0.00024 20.6 13.5 1.6 1 1 1 2 2 2 1 X-domain of DnaJ-containing UCH PF00443.29 KFQ99715.1 - 0.078 12.5 4.5 0.094 12.2 4.5 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF3585 PF12130.8 KFQ99715.1 - 0.4 10.8 13.4 1.2 9.3 13.3 1.9 1 1 0 1 1 1 0 Bivalent Mical/EHBP Rab binding domain Imm42 PF15593.6 KFQ99715.1 - 4.4 7.8 8.1 25 5.3 8.1 2.0 1 1 0 1 1 1 0 Immunity protein 42 SICA_beta PF12878.7 KFQ99715.1 - 5.2 7.2 14.2 16 5.7 14.2 1.8 1 1 0 1 1 1 0 SICA extracellular beta domain RGS-like PF09128.11 KFQ99717.1 - 2.4e-66 223.0 0.1 9.2e-66 221.1 0.0 2.0 2 0 0 2 2 2 1 Regulator of G protein signalling-like domain PH_16 PF17838.1 KFQ99717.1 - 2.4e-48 163.1 0.4 5.7e-48 161.9 0.4 1.7 1 0 0 1 1 1 1 PH domain RhoGEF PF00621.20 KFQ99717.1 - 3.5e-37 128.4 4.8 1.1e-36 126.8 4.8 1.9 1 0 0 1 1 1 1 RhoGEF domain PDZ PF00595.24 KFQ99717.1 - 1.8e-14 53.8 0.3 4.3e-14 52.6 0.3 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFQ99717.1 - 1.1e-12 47.6 0.1 2.8e-12 46.3 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFQ99717.1 - 9.6e-08 32.2 0.1 2.6e-07 30.9 0.1 1.7 1 0 0 1 1 1 1 PDZ domain RGS PF00615.19 KFQ99717.1 - 8.6e-05 22.8 0.0 0.0003 21.1 0.0 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain PH_13 PF16652.5 KFQ99717.1 - 0.00057 19.7 1.2 0.00082 19.2 0.1 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KFQ99717.1 - 0.012 16.2 0.0 0.03 14.8 0.0 1.8 1 0 0 1 1 1 0 PH domain Ribosomal_S30AE PF02482.19 KFQ99717.1 - 0.058 14.2 0.8 1.6 9.6 0.0 2.6 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein Ets PF00178.22 KFQ99718.1 - 2.7e-30 104.7 2.3 4.1e-30 104.1 2.3 1.3 1 0 0 1 1 1 1 Ets-domain RUN PF02759.19 KFQ99743.1 - 9.5e-26 90.4 0.1 1.7e-25 89.5 0.1 1.4 1 0 0 1 1 1 1 RUN domain UPF0054 PF02130.17 KFQ99743.1 - 0.017 14.9 0.1 0.055 13.3 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein family UPF0054 BCMA-Tall_bind PF09257.10 KFQ99744.1 - 4e-19 68.4 13.8 4e-19 68.4 13.8 1.8 2 0 0 2 2 2 1 BCMA, TALL-1 binding LapA_dom PF06305.11 KFQ99744.1 - 0.0038 17.0 0.5 0.0054 16.5 0.5 1.2 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain TACI-CRD2 PF09305.10 KFQ99744.1 - 0.18 11.8 7.1 0.38 10.8 7.1 1.6 1 0 0 1 1 1 0 TACI, cysteine-rich domain GTP_EFTU PF00009.27 KFQ99745.1 - 7.2e-47 159.4 0.0 1.4e-46 158.5 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFQ99745.1 - 3.4e-32 111.1 0.2 3.4e-32 111.1 0.2 2.7 5 0 0 5 5 5 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KFQ99745.1 - 2.5e-08 34.2 0.1 8e-08 32.6 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFQ99745.1 - 0.00062 19.8 0.1 0.0028 17.7 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase LPD34 PF18852.1 KFQ99745.1 - 0.06 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 34 Arf PF00025.21 KFQ99745.1 - 0.062 12.7 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Ribosomal_L1 PF00687.21 KFQ99746.1 - 4e-53 180.2 1.9 4.6e-53 180.0 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family RRN3 PF05327.11 KFQ99747.1 - 2.1e-134 449.1 0.8 2.7e-134 448.8 0.8 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 N_Asn_amidohyd PF14736.6 KFQ99748.1 - 1.4e-121 404.8 0.0 1.6e-121 404.6 0.0 1.0 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase Pyridoxal_deC PF00282.19 KFQ99749.1 - 3.3e-12 45.8 0.0 2.7e-09 36.3 0.0 2.2 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain KIAA1430 PF13879.6 KFQ99749.1 - 2.3 9.0 8.1 23 5.8 0.2 3.6 3 0 0 3 3 3 0 KIAA1430 homologue DUF3585 PF12130.8 KFQ99750.1 - 7.3e-18 65.0 17.0 9.5e-18 64.7 17.0 1.1 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain DUF572 PF04502.13 KFQ99750.1 - 0.022 14.4 4.0 0.025 14.2 4.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) CTI PF06934.11 KFQ99750.1 - 0.024 13.2 0.2 0.029 12.9 0.2 1.1 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) Ribosomal_60s PF00428.19 KFQ99750.1 - 0.083 13.5 0.1 0.083 13.5 0.1 2.0 1 1 1 2 2 2 0 60s Acidic ribosomal protein DUF1151 PF06625.11 KFQ99750.1 - 1.4 8.8 13.2 4.2 7.3 13.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1151) MRPL52 PF18699.1 KFQ99750.1 - 1.8 8.8 9.0 0.54 10.5 3.3 2.2 1 1 1 2 2 2 0 Mitoribosomal protein mL52 Histone_HNS PF00816.21 KFQ99750.1 - 5.2 8.0 7.1 0.68 10.8 3.1 1.7 2 0 0 2 2 2 0 H-NS histone family FlxA PF14282.6 KFQ99750.1 - 5.6 7.0 8.7 0.89 9.6 4.0 2.0 3 0 0 3 3 3 0 FlxA-like protein OST-HTH PF12872.7 KFQ99751.1 - 5.8e-68 224.7 0.6 2.4e-13 49.7 0.0 8.2 8 0 0 8 8 8 6 OST-HTH/LOTUS domain Limkain-b1 PF11608.8 KFQ99751.1 - 1e-40 137.7 0.3 2.9e-40 136.2 0.3 1.8 1 0 0 1 1 1 1 Limkain b1 NYN PF01936.18 KFQ99751.1 - 6.9e-19 68.8 0.0 1.7e-18 67.5 0.0 1.7 1 0 0 1 1 1 1 NYN domain RRM_1 PF00076.22 KFQ99751.1 - 1.1e-08 34.7 0.0 5.6e-05 22.9 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFQ99751.1 - 0.005 16.4 0.0 2.2 7.9 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FlbD PF06289.11 KFQ99751.1 - 0.62 9.7 3.5 1.2 8.8 0.8 2.6 2 0 0 2 2 2 0 Flagellar and Swarming motility proteins NUDE_C PF04880.13 KFQ99752.1 - 9.1e-44 150.0 3.6 9.1e-44 150.0 3.6 2.4 2 0 0 2 2 2 1 NUDE protein, C-terminal conserved region DMPK_coil PF08826.10 KFQ99752.1 - 0.0027 17.8 8.0 0.0027 17.8 8.0 3.9 2 1 0 2 2 1 1 DMPK coiled coil domain like TPR_MLP1_2 PF07926.12 KFQ99752.1 - 0.0094 16.0 34.1 0.093 12.8 9.8 3.2 2 1 1 3 3 3 2 TPR/MLP1/MLP2-like protein PRKG1_interact PF15898.5 KFQ99752.1 - 0.01 16.7 11.1 0.01 16.7 11.1 3.4 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain HIP1_clath_bdg PF16515.5 KFQ99752.1 - 0.015 15.9 10.7 0.015 15.9 10.7 3.0 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 YabA PF06156.13 KFQ99752.1 - 0.18 12.4 24.8 4.2 8.1 5.7 3.6 1 1 2 3 3 3 0 Initiation control protein YabA ATG16 PF08614.11 KFQ99752.1 - 0.45 10.7 39.0 0.76 10.0 21.8 2.4 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) FPP PF05911.11 KFQ99752.1 - 0.89 7.7 29.4 1.6 6.8 18.2 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF5082 PF16888.5 KFQ99752.1 - 2.4 8.5 20.3 0.46 10.8 8.1 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF5082) ADIP PF11559.8 KFQ99752.1 - 3.1 7.9 31.7 0.56 10.3 7.4 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF2514 PF10721.9 KFQ99752.1 - 4.4 7.3 11.1 0.56 10.2 4.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2514) DUF1664 PF07889.12 KFQ99752.1 - 4.9 7.2 11.9 1.1 9.3 4.5 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Titin_Ig-rpts PF06582.12 KFQ99752.1 - 5.9 6.9 9.5 0.6 10.1 0.9 3.4 3 0 0 3 3 3 0 Titin repeat GAS PF13851.6 KFQ99752.1 - 6.3 6.1 34.2 0.52 9.6 20.2 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding PspA_IM30 PF04012.12 KFQ99752.1 - 7.5 6.1 30.3 1.5 8.3 6.7 2.9 1 1 1 2 2 2 0 PspA/IM30 family Fez1 PF06818.15 KFQ99752.1 - 8.8 6.7 30.7 0.23 11.9 11.8 2.3 1 1 1 2 2 2 0 Fez1 Myosin_tail_1 PF01576.19 KFQ99753.1 - 0 1686.2 319.5 0 1685.9 319.5 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_head PF00063.21 KFQ99753.1 - 1.9e-296 984.8 4.0 1.9e-296 984.8 4.0 4.0 4 1 0 4 4 4 1 Myosin head (motor domain) Myosin_N PF02736.19 KFQ99753.1 - 2.1e-15 56.3 1.6 6.4e-15 54.7 1.6 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain IQ PF00612.27 KFQ99753.1 - 0.0004 19.9 1.1 0.00079 19.0 0.2 2.1 2 0 0 2 2 2 1 IQ calmodulin-binding motif CC2-LZ PF16516.5 KFQ99753.1 - 0.00065 20.0 17.2 0.00065 20.0 17.2 18.3 3 2 13 16 16 16 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator ADIP PF11559.8 KFQ99753.1 - 0.0017 18.4 20.2 0.0017 18.4 20.2 15.0 1 1 15 16 16 16 3 Afadin- and alpha -actinin-Binding AAA_22 PF13401.6 KFQ99753.1 - 0.07 13.4 0.0 0.07 13.4 0.0 7.8 6 2 2 8 8 8 0 AAA domain DUF3970 PF13113.6 KFQ99753.1 - 0.51 10.6 7.5 2.4 8.5 1.6 4.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3970) FOP_dimer PF09398.10 KFQ99754.1 - 2.1e-23 82.4 0.1 3.4e-23 81.7 0.1 1.4 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 KFQ99754.1 - 5.4e-06 25.3 0.1 1e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 LisH LisH PF08513.11 KFQ99754.1 - 0.15 12.0 2.1 0.29 11.2 1.1 1.9 2 0 0 2 2 2 0 LisH ABC_membrane PF00664.23 KFQ99755.1 - 1.7e-93 313.3 39.4 2.2e-52 178.4 6.7 2.7 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFQ99755.1 - 7.5e-55 185.2 0.0 3.6e-29 102.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFQ99755.1 - 4.9e-10 39.2 0.1 9.7e-05 21.9 0.0 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KFQ99755.1 - 6.6e-06 26.2 0.5 0.07 13.2 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFQ99755.1 - 8.5e-06 25.8 0.5 0.0028 17.6 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KFQ99755.1 - 8.8e-06 26.2 0.0 0.0016 18.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KFQ99755.1 - 0.00012 21.7 0.3 0.0083 15.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KFQ99755.1 - 0.00069 19.0 1.4 0.003 16.9 0.1 2.2 2 0 0 2 2 2 1 Zeta toxin ABC_ATPase PF09818.9 KFQ99755.1 - 0.00077 18.4 0.0 0.075 11.8 0.0 3.0 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_21 PF13304.6 KFQ99755.1 - 0.002 18.0 1.1 3.2 7.5 0.0 3.7 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 KFQ99755.1 - 0.0034 17.4 2.6 0.028 14.5 0.2 2.8 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.6 KFQ99755.1 - 0.01 16.4 0.6 4.1 7.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFQ99755.1 - 0.011 15.2 0.2 0.45 10.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 KFQ99755.1 - 0.015 15.0 2.3 2.6 7.8 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KFQ99755.1 - 0.018 15.3 3.9 1.9 8.7 0.1 3.8 3 1 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 KFQ99755.1 - 0.028 14.1 0.0 2.3 7.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Roc PF08477.13 KFQ99755.1 - 0.061 13.6 0.8 23 5.2 0.0 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 KFQ99755.1 - 0.068 13.3 2.6 4.7 7.2 0.2 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain NB-ARC PF00931.22 KFQ99755.1 - 0.07 12.3 1.0 11 5.1 0.1 2.7 2 1 0 2 2 2 0 NB-ARC domain DUF815 PF05673.13 KFQ99755.1 - 0.098 11.8 0.3 3.1 6.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.9 KFQ99755.1 - 0.11 11.4 0.6 8.3 5.2 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 KFQ99755.1 - 0.19 11.5 1.4 11 5.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain ABC_membrane PF00664.23 KFQ99756.1 - 1.1e-68 231.9 40.4 2.1e-36 126.0 17.5 2.9 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFQ99756.1 - 5.6e-54 182.4 1.7 5.2e-30 104.8 0.1 3.4 4 0 0 4 4 4 2 ABC transporter SMC_N PF02463.19 KFQ99756.1 - 9e-11 41.6 0.0 2.5e-05 23.8 0.0 3.5 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KFQ99756.1 - 4e-06 26.9 0.9 0.0099 16.0 0.1 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFQ99756.1 - 1.6e-05 24.9 0.2 0.004 17.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KFQ99756.1 - 3.2e-05 24.2 4.1 0.083 13.2 0.3 3.3 3 1 0 3 3 2 2 AAA domain AAA_29 PF13555.6 KFQ99756.1 - 6.2e-05 22.7 0.7 0.26 11.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KFQ99756.1 - 0.00011 22.6 2.0 0.031 14.6 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 KFQ99756.1 - 0.00018 20.7 0.2 0.24 10.4 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein Dynamin_N PF00350.23 KFQ99756.1 - 0.00022 21.3 2.4 0.01 15.9 0.0 3.9 4 0 0 4 4 4 1 Dynamin family Zeta_toxin PF06414.12 KFQ99756.1 - 0.00039 19.8 0.3 0.12 11.7 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin ABC_ATPase PF09818.9 KFQ99756.1 - 0.0014 17.6 0.3 1.3 7.8 0.1 3.3 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 KFQ99756.1 - 0.0028 17.2 0.8 0.51 9.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KFQ99756.1 - 0.016 14.2 0.5 1.6 7.6 0.1 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 KFQ99756.1 - 0.033 13.7 0.4 3.1 7.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_21 PF13304.6 KFQ99756.1 - 0.046 13.5 1.6 3.1 7.5 0.1 3.4 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 KFQ99756.1 - 0.078 12.6 2.7 2.5 7.7 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KFQ99756.1 - 0.086 13.4 0.0 1.3 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFQ99756.1 - 0.097 12.4 3.8 5.5 6.6 0.2 2.9 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 KFQ99756.1 - 0.12 12.4 1.3 17 5.5 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TrwB_AAD_bind PF10412.9 KFQ99756.1 - 0.14 11.1 3.1 1.3 7.9 0.3 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.9 KFQ99756.1 - 0.21 10.8 2.3 3.1 7.0 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 KFQ99756.1 - 0.23 11.3 1.3 3.1 7.7 0.1 2.4 2 0 0 2 2 2 0 NTPase CbiA PF01656.23 KFQ99756.1 - 0.43 10.6 1.5 1.4 9.0 0.1 2.6 4 0 0 4 4 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NB-ARC PF00931.22 KFQ99756.1 - 0.49 9.5 3.1 14 4.8 0.2 3.2 3 0 0 3 3 3 0 NB-ARC domain DUF87 PF01935.17 KFQ99756.1 - 0.52 10.4 10.9 0.32 11.0 0.3 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_23 PF13476.6 KFQ99756.1 - 4.3 7.8 10.8 2 8.9 0.0 3.2 4 0 0 4 4 2 0 AAA domain CarboxypepD_reg PF13620.6 KFQ99757.1 - 5.5e-46 154.7 3.6 9.5e-09 35.4 0.2 9.5 9 1 0 9 9 9 7 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 KFQ99757.1 - 7.2e-28 97.1 1.6 0.00033 20.8 0.0 9.3 9 0 0 9 9 9 6 SdrD B-like domain DUF2012 PF09430.10 KFQ99757.1 - 2.1e-23 82.7 0.2 1.8e-07 31.3 0.0 7.7 7 1 1 8 8 8 4 Protein of unknown function (DUF2012) CarbopepD_reg_2 PF13715.6 KFQ99757.1 - 2.4e-18 65.9 6.8 2.2e-05 24.4 0.3 8.4 8 0 0 8 8 8 4 CarboxypepD_reg-like domain SpaA PF17802.1 KFQ99757.1 - 1.2e-15 57.6 4.1 0.0013 19.0 0.0 7.0 8 0 0 8 8 8 3 Prealbumin-like fold domain fn3_3 PF14686.6 KFQ99757.1 - 1.6e-13 50.2 0.0 0.0022 17.8 0.0 7.1 7 0 0 7 7 7 3 Polysaccharide lyase family 4, domain II Y_Y_Y PF07495.13 KFQ99757.1 - 8.8e-07 28.8 0.7 1.3 9.1 0.0 5.2 5 0 0 5 5 5 1 Y_Y_Y domain DUF2846 PF11008.8 KFQ99757.1 - 1.7e-05 24.7 0.3 13 5.9 0.0 5.1 6 0 0 6 6 5 0 Protein of unknown function (DUF2846) DUF3823 PF12866.7 KFQ99757.1 - 3.3e-05 24.1 0.2 0.14 12.5 0.0 4.7 4 0 0 4 4 4 1 Protein of unknown function (DUF3823) N-terminal domain Dioxygenase_C PF00775.21 KFQ99757.1 - 0.00019 20.9 0.0 12 5.2 0.0 5.1 5 1 0 5 5 5 1 Dioxygenase TTR-52 PF01060.23 KFQ99757.1 - 0.0034 18.0 0.1 26 5.6 0.0 4.9 5 0 0 5 5 5 0 Transthyretin-like family Cupredoxin_1 PF13473.6 KFQ99757.1 - 0.065 13.3 0.0 2.6 8.2 0.0 3.6 2 1 1 3 3 3 0 Cupredoxin-like domain DUF2141 PF09912.9 KFQ99757.1 - 0.087 12.7 0.0 17 5.4 0.0 4.0 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2141) MetallophosN PF16371.5 KFQ99757.1 - 0.2 12.0 1.6 30 5.0 0.0 4.5 5 0 0 5 5 5 0 N terminal of Calcineurin-like phosphoesterase Xylo_C PF12529.8 KFQ99759.1 - 1.6e-67 226.6 0.0 2.9e-67 225.8 0.0 1.4 1 0 0 1 1 1 1 Xylosyltransferase C terminal Branch PF02485.21 KFQ99759.1 - 1.7e-46 158.8 0.6 3e-46 157.9 0.6 1.4 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Ribosomal_S8 PF00410.19 KFQ99760.1 - 1.9e-22 79.6 0.0 2.6e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Reticulon PF02453.17 KFQ99761.1 - 0.0024 17.8 4.1 0.0033 17.4 4.1 1.1 1 0 0 1 1 1 1 Reticulon BCL_N PF04714.13 KFQ99761.1 - 0.44 10.6 0.1 0.44 10.6 0.1 2.5 3 0 0 3 3 3 0 BCL7, N-terminal conserver region SMG1 PF15785.5 KFQ99762.1 - 2.8e-256 851.9 12.7 5.7e-256 850.9 9.1 2.6 2 0 0 2 2 2 1 Serine/threonine-protein kinase smg-1 PI3_PI4_kinase PF00454.27 KFQ99762.1 - 1.1e-52 179.4 0.0 2.8e-52 178.0 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SMG1_N PF17229.2 KFQ99762.1 - 5.1e-49 165.4 4.5 1.1e-48 164.4 4.5 1.6 1 0 0 1 1 1 1 Serine/threonine-protein kinase SMG1 N-terminal FATC PF02260.20 KFQ99762.1 - 5e-12 45.4 0.1 2.6e-11 43.1 0.1 2.4 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 KFQ99762.1 - 0.038 14.3 0.4 0.78 10.2 0.0 3.4 2 0 0 2 2 2 0 HEAT repeat HEAT_2 PF13646.6 KFQ99762.1 - 0.054 13.9 0.2 11 6.5 0.0 3.6 3 0 0 3 3 3 0 HEAT repeats FRB_dom PF08771.11 KFQ99762.1 - 0.79 10.2 12.6 3.6 8.1 1.5 5.1 3 1 0 3 3 3 0 FKBP12-rapamycin binding domain Lectin_C PF00059.21 KFQ99763.1 - 6.7e-19 68.6 0.3 8.2e-19 68.3 0.3 1.1 1 0 0 1 1 1 1 Lectin C-type domain C2 PF00168.30 KFQ99764.1 - 1.1e-42 144.5 0.1 1.4e-21 76.7 0.0 2.2 2 0 0 2 2 2 2 C2 domain Mab-21 PF03281.14 KFQ99765.1 - 5.3e-17 62.1 0.0 6.4e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein DUF4684 PF15736.5 KFQ99765.1 - 0.064 11.9 0.1 0.084 11.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) COQ7 PF03232.13 KFQ99766.1 - 1.1e-75 253.2 0.0 1.2e-75 253.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 KFQ99766.1 - 0.00045 20.6 0.1 0.014 15.8 0.1 2.1 1 1 0 1 1 1 1 Rubrerythrin Tsc35 PF15079.6 KFQ99766.1 - 0.041 13.5 0.8 0.055 13.0 0.1 1.5 2 0 0 2 2 2 0 Testis-specific protein 35 Muraidase PF11860.8 KFQ99766.1 - 0.076 13.2 0.2 1.5 9.1 0.0 2.2 2 1 0 2 2 2 0 N-acetylmuramidase Ferritin_2 PF13668.6 KFQ99766.1 - 0.082 13.1 0.2 15 5.8 0.0 2.3 1 1 1 2 2 2 0 Ferritin-like domain TMC PF07810.13 KFQ99768.1 - 1.1e-37 129.0 1.5 1.1e-37 129.0 1.5 3.4 3 1 0 3 3 3 1 TMC domain GDPD PF03009.17 KFQ99769.1 - 4e-23 82.5 0.1 1.3e-22 80.8 0.1 1.7 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CALM_bind PF16025.5 KFQ99770.1 - 7e-20 71.3 9.9 3.1e-19 69.2 1.0 4.7 4 1 1 5 5 5 2 Calcium-dependent calmodulin binding DUF2344 PF10105.9 KFQ99770.1 - 6.4 6.6 14.0 5.7 6.7 3.9 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2344) SMAP PF15477.6 KFQ99771.1 - 1.2e-13 51.8 2.1 1.2e-13 51.8 2.1 2.3 2 1 0 2 2 2 1 Small acidic protein family 7tm_1 PF00001.21 KFQ99773.1 - 4e-23 82.1 28.6 5.3e-23 81.7 28.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFQ99773.1 - 5.5e-09 35.7 29.0 6.8e-05 22.3 13.0 2.2 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 KFQ99773.1 - 7.7e-08 32.3 28.2 7.7e-08 32.3 28.2 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Thioredoxin_6 PF13848.6 KFQ99774.1 - 1.1e-35 123.2 3.7 3e-32 112.0 1.6 2.1 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 KFQ99774.1 - 3.9e-13 49.3 0.1 3.9e-09 36.4 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin OST3_OST6 PF04756.13 KFQ99774.1 - 2.2e-08 33.8 0.2 0.00012 21.5 0.1 2.1 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family AMP-binding PF00501.28 KFQ99775.1 - 3.9e-79 266.2 0.0 4.8e-79 265.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFQ99775.1 - 3.4e-23 82.4 0.1 3.4e-22 79.2 0.3 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain THUMP PF02926.17 KFQ99776.1 - 2.5e-23 82.8 1.0 4.3e-23 82.0 0.7 1.5 1 1 0 1 1 1 1 THUMP domain AMP-binding PF00501.28 KFQ99777.1 - 3.3e-82 276.3 0.0 4e-82 276.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFQ99777.1 - 4.3e-24 85.3 0.9 8.2e-24 84.4 0.9 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SRI PF08236.11 KFQ99777.1 - 0.12 12.5 1.0 0.3 11.3 1.0 1.7 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain RNase_T PF00929.24 KFQ99778.1 - 4.4e-25 89.1 0.0 6.1e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Exonuclease RRM_1 PF00076.22 KFQ99779.1 - 2.3e-20 72.2 0.0 2.6e-12 46.4 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 KFQ99779.1 - 1.8e-06 28.6 0.0 5.6e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 Exonuclease EzrA PF06160.12 KFQ99779.1 - 0.061 11.5 0.1 0.12 10.5 0.1 1.4 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TMF_DNA_bd PF12329.8 KFQ99779.1 - 0.42 10.6 8.6 0.032 14.2 3.0 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Cullin_binding PF03556.15 KFQ99780.1 - 5.1e-33 114.1 0.2 9e-33 113.3 0.2 1.4 1 0 0 1 1 1 1 Cullin binding Complex1_LYR PF05347.15 KFQ99781.1 - 4.7e-14 52.2 0.1 7.6e-14 51.5 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFQ99781.1 - 0.0071 17.1 0.3 0.0089 16.8 0.3 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Promethin PF16015.5 KFQ99782.1 - 2.1e-23 82.2 12.5 2.5e-23 82.0 12.5 1.1 1 0 0 1 1 1 1 Promethin CcmH PF03918.14 KFQ99782.1 - 0.039 13.3 0.0 0.089 12.1 0.0 1.6 2 0 0 2 2 2 0 Cytochrome C biogenesis protein DUF2207 PF09972.9 KFQ99782.1 - 0.041 12.6 3.5 0.065 12.0 3.5 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Zona_pellucida PF00100.23 KFQ99783.1 - 2.6e-47 161.8 0.1 9.8e-47 159.9 0.0 2.0 2 0 0 2 2 2 1 Zona pellucida-like domain Ank_2 PF12796.7 KFQ99784.1 - 1.5e-16 60.7 0.5 6.1e-15 55.6 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFQ99784.1 - 6.4e-15 55.0 2.6 2.4e-08 34.1 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFQ99784.1 - 4.2e-14 52.7 1.2 3.3e-05 24.3 0.1 3.5 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KFQ99784.1 - 1.4e-10 41.1 0.9 2.1e-08 34.2 0.3 3.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 KFQ99784.1 - 1.1e-09 37.7 0.7 3.3e-05 23.9 0.2 4.0 4 0 0 4 4 4 1 Ankyrin repeat SAM_1 PF00536.30 KFQ99784.1 - 6e-07 29.8 0.0 1.5e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFQ99784.1 - 0.0085 16.2 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ribosomal_S18 PF01084.20 KFQ99784.1 - 0.021 15.0 0.3 0.054 13.7 0.3 1.6 1 0 0 1 1 1 0 Ribosomal protein S18 OCD_Mu_crystall PF02423.15 KFQ99785.1 - 1.2e-90 303.7 0.4 1.3e-90 303.6 0.4 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KFQ99785.1 - 8.5e-09 35.6 0.0 1.3e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 KFQ99785.1 - 0.00016 21.9 0.9 0.0015 18.7 0.6 2.5 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KFQ99785.1 - 0.00016 22.2 0.1 0.00048 20.7 0.0 1.8 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Peptidase_M16 PF00675.20 KFQ99786.1 - 5.9e-31 107.5 0.0 1e-30 106.7 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFQ99786.1 - 3.7e-23 82.5 0.1 2e-22 80.1 0.0 2.2 3 0 0 3 3 3 1 Peptidase M16 inactive domain Atthog PF18800.1 KFQ99787.1 - 3.2e-62 208.6 4.1 3.5e-62 208.4 4.1 1.0 1 0 0 1 1 1 1 Attenuator of Hedgehog 7tm_3 PF00003.22 KFQ99787.1 - 5.1e-05 23.1 4.7 5.6e-05 23.0 4.7 1.0 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Cyt_bd_oxida_I PF01654.17 KFQ99787.1 - 0.00017 20.3 4.0 0.00021 20.1 4.0 1.1 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I LtrA PF06772.11 KFQ99787.1 - 0.0015 17.8 0.5 0.0018 17.6 0.5 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF423 PF04241.15 KFQ99787.1 - 0.057 13.6 0.9 0.057 13.6 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF423) DUF998 PF06197.13 KFQ99787.1 - 0.073 12.7 7.1 0.2 11.2 7.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF998) L_HMGIC_fpl PF10242.9 KFQ99787.1 - 0.094 12.9 5.8 0.15 12.2 5.5 1.6 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein TctB PF07331.11 KFQ99787.1 - 0.28 11.5 10.9 0.95 9.7 10.9 1.8 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF3784 PF12650.7 KFQ99787.1 - 0.9 9.8 11.7 2.6 8.3 11.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3784) DUF2721 PF11026.8 KFQ99787.1 - 1.5 8.7 10.3 1.7 8.6 4.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF456 PF04306.13 KFQ99787.1 - 2.4 8.4 11.4 16 5.7 11.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF456) VWA_3 PF13768.6 KFQ99788.1 - 5.9e-56 188.7 0.1 5e-22 78.5 0.0 3.5 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA PF00092.28 KFQ99788.1 - 1.4e-14 54.7 0.0 3.6e-10 40.4 0.0 2.9 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA_2 PF13519.6 KFQ99788.1 - 1.7e-11 44.7 0.0 5.4e-05 23.8 0.0 3.8 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA_CoxE PF05762.14 KFQ99788.1 - 0.014 14.8 0.1 0.36 10.2 0.0 2.5 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein 3Beta_HSD PF01073.19 KFQ99789.1 - 1.9e-60 204.3 0.0 2.5e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFQ99789.1 - 2e-23 83.1 0.0 2.8e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFQ99789.1 - 9.6e-12 44.9 0.0 7.6e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KFQ99789.1 - 7.6e-10 38.4 0.0 1.4e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KFQ99789.1 - 9e-08 31.6 0.0 2.3e-07 30.3 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KFQ99789.1 - 4.4e-07 30.0 0.0 6.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KFQ99789.1 - 4.8e-05 22.6 0.0 6.9e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 KFQ99789.1 - 0.027 14.0 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family SWI2_SNF2 PF18766.1 KFQ99789.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 SWI2/SNF2 ATPase 3Beta_HSD PF01073.19 KFQ99790.1 - 1.8e-66 224.1 0.0 2.1e-66 223.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFQ99790.1 - 1.1e-26 93.8 0.0 1.4e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFQ99790.1 - 4.5e-13 49.3 0.0 1.1e-12 48.0 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KFQ99790.1 - 2.8e-09 36.5 0.0 3.7e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KFQ99790.1 - 5.7e-08 32.9 0.0 7.2e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KFQ99790.1 - 7e-08 31.9 0.4 3.3e-07 29.7 0.4 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KFQ99790.1 - 1.9e-07 30.5 0.0 5e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KFQ99790.1 - 2.9e-05 23.7 0.0 5.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KFQ99790.1 - 0.0055 16.2 0.1 0.008 15.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Alpha_kinase PF02816.18 KFQ99791.1 - 2e-60 204.1 0.2 3.3e-60 203.4 0.2 1.4 1 0 0 1 1 1 1 Alpha-kinase family Sel1 PF08238.12 KFQ99791.1 - 5.6e-07 30.0 7.2 0.37 11.6 0.1 5.1 5 0 0 5 5 5 3 Sel1 repeat Sin_N PF04801.13 KFQ99792.1 - 2.7e-156 521.1 2.9 2.7e-156 521.1 2.9 2.2 3 0 0 3 3 3 1 Sin-like protein conserved region ATG13 PF10033.9 KFQ99792.1 - 0.51 10.0 3.1 0.16 11.6 0.2 1.6 2 0 0 2 2 2 0 Autophagy-related protein 13 ZapB PF06005.12 KFQ99793.1 - 0.0081 16.6 2.1 0.0081 16.6 2.1 6.3 4 3 2 6 6 6 2 Cell division protein ZapB DUF724 PF05266.14 KFQ99793.1 - 0.011 15.5 0.5 0.011 15.5 0.5 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF724) DUF4618 PF15397.6 KFQ99793.1 - 0.16 11.4 37.6 0.091 12.2 14.8 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4618) ATG16 PF08614.11 KFQ99793.1 - 0.23 11.7 38.6 0.24 11.6 5.5 3.5 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) APC_N_CC PF16689.5 KFQ99793.1 - 0.3 11.2 12.1 2.1 8.5 0.3 5.0 4 1 0 4 4 4 0 Coiled-coil N-terminus of APC, dimerisation domain GIT_CC PF16559.5 KFQ99793.1 - 0.31 10.9 22.7 1.1 9.2 1.0 4.6 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Jnk-SapK_ap_N PF09744.9 KFQ99793.1 - 0.31 11.3 45.2 0.022 15.0 17.5 3.9 2 1 2 4 4 4 0 JNK_SAPK-associated protein-1 UPF0242 PF06785.11 KFQ99793.1 - 0.41 10.7 41.1 3.6 7.7 5.5 3.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus NPV_P10 PF05531.12 KFQ99793.1 - 1.5 9.3 0.0 1.5 9.3 0.0 4.4 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Baculo_IE-1 PF05290.11 KFQ99793.1 - 4.9 7.1 9.3 9.4 6.2 0.7 3.2 3 1 0 3 3 3 0 Baculovirus immediate-early protein (IE-0) DUF4795 PF16043.5 KFQ99793.1 - 5.1 6.6 37.4 28 4.2 1.4 4.1 2 2 0 2 2 2 0 Domain of unknown function (DUF4795) PHM7_cyt PF14703.6 KFQ99793.1 - 6 7.1 25.9 0.12 12.6 3.2 3.1 2 2 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter HALZ PF02183.18 KFQ99793.1 - 6.6 7.0 26.5 3.3 8.0 0.6 6.3 5 0 0 5 5 5 0 Homeobox associated leucine zipper FUSC PF04632.12 KFQ99793.1 - 7.1 5.0 5.6 14 4.1 5.6 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Vps51 PF08700.11 KFQ99793.1 - 9.2 6.4 19.1 0.36 10.9 5.2 4.3 3 2 1 4 4 4 0 Vps51/Vps67 MFS_2 PF13347.6 KFQ99794.1 - 1.9e-35 122.3 22.3 2.3e-35 122.0 22.3 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein DREV PF05219.12 KFQ99795.1 - 4.7e-130 432.4 0.0 5.3e-130 432.2 0.0 1.0 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.6 KFQ99795.1 - 7.1e-12 45.5 0.0 1e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFQ99795.1 - 7.4e-09 36.2 0.0 1.2e-08 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFQ99795.1 - 6.4e-07 29.9 0.0 1.1e-06 29.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFQ99795.1 - 7.3e-06 26.6 0.0 1.5e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFQ99795.1 - 0.04 13.7 0.0 0.086 12.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KFQ99795.1 - 0.099 12.2 0.0 3.1 7.3 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase small domain V-set PF07686.17 KFQ99796.1 - 1.1e-07 32.0 0.6 3.5e-07 30.4 0.5 1.9 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFQ99796.1 - 0.00011 22.7 0.1 0.00022 21.7 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFQ99796.1 - 0.0044 17.2 0.4 0.01 16.0 0.4 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFQ99796.1 - 0.011 15.8 0.0 0.02 15.0 0.0 1.5 1 1 0 1 1 1 0 Immunoglobulin I-set domain NuA4 PF09340.10 KFQ99797.1 - 0.068 13.1 0.1 0.24 11.3 0.1 2.0 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 FliG_M PF14841.6 KFQ99797.1 - 0.069 13.4 0.0 3.9 7.8 0.0 3.4 3 0 0 3 3 3 0 FliG middle domain ER_lumen_recept PF00810.18 KFQ99798.1 - 4e-54 183.4 9.1 4e-54 183.4 9.1 1.3 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KFQ99798.1 - 0.031 14.1 1.3 0.031 14.1 1.3 2.8 3 2 2 5 5 5 0 PQ loop repeat Ras PF00071.22 KFQ99799.1 - 1.9e-50 170.6 0.0 2.2e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ99799.1 - 6.3e-19 68.4 0.0 8.5e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ99799.1 - 2.5e-05 23.8 0.0 3.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFQ99799.1 - 0.022 14.3 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain CagD PF16567.5 KFQ99799.1 - 0.029 14.1 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 Pathogenicity island component CagD Sec7 PF01369.20 KFQ99800.1 - 1.4e-73 246.5 0.2 1.8e-73 246.1 0.2 1.1 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 KFQ99800.1 - 1.8e-28 99.1 0.1 3.7e-28 98.1 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFQ99800.1 - 4e-05 24.0 1.9 7e-05 23.2 0.2 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 KFQ99800.1 - 0.022 14.8 0.0 0.085 13.0 0.0 2.1 1 1 0 1 1 1 0 PH domain PH_8 PF15409.6 KFQ99800.1 - 0.034 14.4 0.0 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain GPS2_interact PF15784.5 KFQ99800.1 - 0.54 10.7 4.5 0.58 10.6 3.0 1.8 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain UCH PF00443.29 KFQ99801.1 - 1e-48 166.1 1.5 1e-48 166.1 1.5 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFQ99801.1 - 5.1e-19 69.0 4.1 5.1e-19 69.0 4.1 3.7 3 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase zf_UBZ PF18439.1 KFQ99801.1 - 0.13 11.9 3.9 0.28 10.8 0.2 2.8 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Pkinase PF00069.25 KFQ99802.1 - 2.9e-46 158.0 0.8 2.9e-29 102.2 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ99802.1 - 1.8e-25 89.7 0.8 1.8e-24 86.4 0.8 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase SlyX PF04102.12 KFQ99802.1 - 0.011 16.3 2.0 0.03 14.9 2.0 1.8 1 0 0 1 1 1 0 SlyX DUF641 PF04859.12 KFQ99802.1 - 0.013 15.9 1.4 0.035 14.4 1.4 1.7 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Kdo PF06293.14 KFQ99802.1 - 0.027 13.8 0.1 0.057 12.8 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KFQ99802.1 - 0.029 14.0 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF16 PF01519.16 KFQ99802.1 - 0.036 14.5 2.5 0.054 14.0 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 TMF_TATA_bd PF12325.8 KFQ99802.1 - 0.089 13.0 3.8 0.24 11.6 3.8 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding P4Ha_N PF08336.11 KFQ99802.1 - 0.12 12.4 1.2 0.27 11.2 1.2 1.6 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Csm1_N PF18504.1 KFQ99802.1 - 0.19 12.1 2.8 0.48 10.8 2.8 1.6 1 0 0 1 1 1 0 Csm1 N-terminal domain DivIC PF04977.15 KFQ99802.1 - 0.22 11.3 3.7 0.23 11.3 1.9 1.9 2 0 0 2 2 2 0 Septum formation initiator APH PF01636.23 KFQ99802.1 - 2.5 7.9 4.8 0.49 10.3 0.5 1.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family Thioredoxin_16 PF18569.1 KFQ99803.1 - 3.2e-38 129.7 0.3 5.6e-38 129.0 0.3 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain GST_C PF00043.25 KFQ99803.1 - 5.2e-07 29.8 0.0 1.1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFQ99803.1 - 6.9e-06 26.0 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFQ99803.1 - 1.4e-05 25.2 0.0 7.5e-05 22.9 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KFQ99803.1 - 0.0032 17.2 0.0 0.0072 16.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MutL_C PF08676.11 KFQ99804.1 - 3.7e-31 107.9 0.0 8.8e-31 106.7 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KFQ99804.1 - 1.7e-23 82.5 0.0 1.7e-23 82.5 0.0 2.4 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KFQ99804.1 - 8.8e-12 45.0 0.1 2.1e-11 43.8 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KFQ99804.1 - 8.7e-06 26.2 0.1 2.7e-05 24.7 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MORN PF02493.20 KFQ99805.1 - 2.5e-17 61.6 32.0 1.9e-08 33.7 0.9 5.3 5 1 0 5 5 5 5 MORN repeat Tudor_2 PF18104.1 KFQ99805.1 - 0.01 15.5 0.3 2.3 8.0 0.0 2.9 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain CCDC50_N PF15295.6 KFQ99806.1 - 1.3 9.1 11.6 3.5 7.8 11.2 1.8 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus DUF3811 PF11656.8 KFQ99806.1 - 2.6 8.5 9.5 0.52 10.7 2.9 2.6 2 1 0 2 2 2 0 YjbD family (DUF3811) DUF1712 PF08217.11 KFQ99807.1 - 1.9e-95 320.6 8.1 1.1e-85 288.3 1.2 2.1 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1712) EF-hand_7 PF13499.6 KFQ99808.1 - 9.1e-15 54.9 0.6 1.3e-14 54.4 0.6 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFQ99808.1 - 3e-14 51.4 2.5 5.8e-07 28.6 0.7 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFQ99808.1 - 3.3e-12 45.3 2.3 4.7e-06 26.1 0.7 3.0 2 1 1 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KFQ99808.1 - 4.2e-11 41.8 2.3 1.4e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFQ99808.1 - 2.1e-06 27.5 0.1 0.04 13.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFQ99808.1 - 0.037 14.3 0.1 0.064 13.6 0.1 1.5 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Toprim_2 PF13155.6 KFQ99808.1 - 0.04 14.3 0.0 8 7.0 0.0 2.1 1 1 1 2 2 2 0 Toprim-like EF-hand_10 PF14788.6 KFQ99808.1 - 0.23 11.3 2.7 0.58 10.1 0.6 2.4 2 1 0 2 2 2 0 EF hand EF-hand_1 PF00036.32 KFQ99809.1 - 3.6e-13 48.1 2.1 6.6e-06 25.3 0.6 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFQ99809.1 - 9.3e-13 48.4 0.1 1.3e-12 48.0 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFQ99809.1 - 2.8e-12 45.5 0.6 4.8e-06 26.1 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KFQ99809.1 - 1.7e-11 43.1 3.2 2.8e-05 23.4 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFQ99809.1 - 5.4e-06 26.1 0.7 4.2e-05 23.3 0.2 2.2 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFQ99809.1 - 0.0067 16.7 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Skp1 PF01466.19 KFQ99809.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Skp1 family, dimerisation domain RuvC PF02075.17 KFQ99809.1 - 0.078 12.8 0.0 0.083 12.8 0.0 1.2 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC EFhand_Ca_insen PF08726.10 KFQ99809.1 - 0.082 13.0 0.4 0.32 11.1 0.1 2.0 2 0 0 2 2 2 0 Ca2+ insensitive EF hand Pkinase_Tyr PF07714.17 KFQ99810.1 - 2.1e-54 184.6 0.0 3.1e-54 184.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFQ99810.1 - 1.8e-27 96.3 0.0 3.8e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain pXO2-72 PF17443.2 KFQ99810.1 - 0.12 12.6 0.4 7.3 6.9 0.2 2.5 2 0 0 2 2 2 0 Uncharacterized protein pXO2-72 HLH PF00010.26 KFQ99811.1 - 3e-17 62.3 4.1 6.9e-17 61.1 4.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Myb_DNA-bind_2 PF08914.11 KFQ99811.1 - 0.054 13.7 1.6 0.054 13.7 1.6 1.8 2 0 0 2 2 2 0 Rap1 Myb domain Hyd_WA PF06462.12 KFQ99812.1 - 2.1e-66 219.5 64.2 1.2e-11 44.3 3.2 11.1 12 0 0 12 12 12 8 Propeller Pex24p PF06398.11 KFQ99812.1 - 7.5e-22 77.8 21.1 4.7e-12 45.6 4.1 2.2 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin PH PF00169.29 KFQ99812.1 - 0.0011 19.4 0.2 0.0038 17.7 0.2 1.9 1 0 0 1 1 1 1 PH domain DUF2367 PF10164.9 KFQ99813.1 - 1.2e-37 128.5 6.0 1.3e-37 128.5 6.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) DUF4126 PF13548.6 KFQ99813.1 - 0.028 14.1 1.2 0.031 14.0 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4126) zf-RING_4 PF14570.6 KFQ99813.1 - 0.035 13.9 1.0 4.8 7.0 0.2 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ribbon_3 PF13248.6 KFQ99813.1 - 0.12 11.9 0.2 0.12 11.9 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 KFQ99813.1 - 0.13 12.0 3.3 7.4 6.4 0.0 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf_Rg PF17915.1 KFQ99813.1 - 0.18 11.2 4.5 1.1 8.7 0.3 2.2 2 0 0 2 2 2 0 Reverse gyrase zinc finger DUF1936 PF09151.10 KFQ99813.1 - 0.45 10.5 0.4 0.45 10.5 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) IMD PF08397.11 KFQ99814.1 - 2.3e-58 197.2 3.7 2.8e-58 196.9 3.7 1.1 1 0 0 1 1 1 1 IRSp53/MIM homology domain SH3_9 PF14604.6 KFQ99814.1 - 8.4e-11 41.6 0.0 1.6e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFQ99814.1 - 1.6e-07 30.9 0.0 3.1e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFQ99814.1 - 2.6e-06 26.9 0.0 5e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Rhabdo_M1 PF03342.13 KFQ99814.1 - 0.038 13.4 0.6 0.098 12.0 0.4 1.9 2 0 0 2 2 2 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) OrfB_IS605 PF01385.19 KFQ99814.1 - 0.14 12.4 0.1 0.14 12.4 0.1 2.3 1 1 1 2 2 2 0 Probable transposase LMBR1 PF04791.16 KFQ99814.1 - 1.5 7.6 3.4 2.4 7.0 3.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Pentaxin PF00354.17 KFQ99815.1 - 4.5e-34 117.8 0.0 6.6e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.6 KFQ99815.1 - 3.6e-14 53.2 0.0 5.4e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily SlyX PF04102.12 KFQ99815.1 - 4.3e-05 24.0 9.5 0.15 12.7 0.1 3.9 3 1 0 3 3 3 2 SlyX LIAS_N PF16881.5 KFQ99815.1 - 0.011 16.1 0.4 0.048 14.1 0.1 2.1 1 1 1 2 2 2 0 N-terminal domain of lipoyl synthase of Radical_SAM family Sun2_CC2 PF18580.1 KFQ99815.1 - 0.031 14.5 3.1 0.16 12.2 0.9 2.5 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 T3SS_basalb_I PF17001.5 KFQ99815.1 - 0.061 13.9 2.1 0.073 13.7 0.2 2.1 2 1 1 3 3 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI Laminin_G_2 PF02210.24 KFQ99815.1 - 0.13 12.8 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain GOLGA2L5 PF15070.6 KFQ99815.1 - 0.18 10.4 9.2 0.25 9.9 9.2 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 DLP_helical PF18709.1 KFQ99815.1 - 0.2 10.8 1.8 0.26 10.4 0.2 1.7 1 1 1 2 2 2 0 Dynamin-like helical domain DUF1664 PF07889.12 KFQ99815.1 - 0.22 11.6 2.0 25 4.9 0.0 2.9 3 1 0 3 3 2 0 Protein of unknown function (DUF1664) JIP_LZII PF16471.5 KFQ99815.1 - 0.35 11.1 8.5 0.95 9.7 4.1 2.9 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II PspB PF06667.12 KFQ99815.1 - 0.83 9.8 0.1 0.83 9.8 0.1 2.3 2 1 1 3 3 3 0 Phage shock protein B Apolipoprotein PF01442.18 KFQ99815.1 - 1.3 8.8 14.2 5.4 6.9 14.2 2.1 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain GrpE PF01025.19 KFQ99815.1 - 1.5 8.4 5.9 6.1 6.5 5.9 1.9 1 1 0 1 1 1 0 GrpE FliD_N PF02465.18 KFQ99815.1 - 1.7 9.4 4.3 6.3 7.6 0.1 2.8 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus bZIP_1 PF00170.21 KFQ99815.1 - 2 8.6 10.2 1.4 9.1 1.2 3.2 3 1 0 3 3 3 0 bZIP transcription factor ABC_tran_CTD PF16326.5 KFQ99815.1 - 3 8.1 11.3 0.85 9.9 1.2 2.8 2 1 1 3 3 3 0 ABC transporter C-terminal domain CCDC-167 PF15188.6 KFQ99815.1 - 6.2 7.2 7.5 41 4.6 7.5 2.3 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 CLZ PF16526.5 KFQ99815.1 - 6.3 7.2 9.5 2.3 8.6 0.1 2.7 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Baculo_PEP_C PF04513.12 KFQ99815.1 - 6.8 6.7 6.0 2.4 8.2 2.5 2.0 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PKD PF00801.20 KFQ99817.1 - 9.9e-08 31.7 0.1 0.013 15.3 0.0 2.8 2 0 0 2 2 2 2 PKD domain Fam20C PF06702.12 KFQ99820.1 - 2.2e-106 354.6 0.2 3.1e-106 354.1 0.2 1.2 1 0 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 Forkhead PF00250.18 KFQ99821.1 - 2.3e-37 127.1 0.2 2.8e-37 126.8 0.2 1.1 1 0 0 1 1 1 1 Forkhead domain DUF3277 PF11681.8 KFQ99821.1 - 0.057 13.3 0.0 0.071 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) PDGF PF00341.17 KFQ99822.1 - 1.1e-21 76.9 10.1 1.7e-21 76.3 10.1 1.3 1 0 0 1 1 1 1 PDGF/VEGF domain PDGF_N PF04692.13 KFQ99822.1 - 7.3e-06 26.7 1.7 1e-05 26.2 0.1 1.9 2 0 0 2 2 2 1 Platelet-derived growth factor, N terminal region cNMP_binding PF00027.29 KFQ99823.1 - 1.6e-42 143.5 0.1 1.8e-20 72.8 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 KFQ99823.1 - 7.5e-14 51.1 0.1 1.5e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DUF5582 PF17819.1 KFQ99823.1 - 0.017 15.6 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5582) DUF5586 PF17824.1 KFQ99823.1 - 0.15 11.2 1.0 0.26 10.3 0.7 1.5 1 1 1 2 2 2 0 Family of unknown function (DUF5586) HEAT_2 PF13646.6 KFQ99824.1 - 2.9e-12 46.8 0.1 0.00014 22.1 0.0 5.4 3 2 1 5 5 5 2 HEAT repeats Vac14_Fab1_bd PF12755.7 KFQ99824.1 - 1e-09 38.8 1.7 0.081 13.5 0.0 5.4 3 2 2 5 5 5 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KFQ99824.1 - 1e-06 29.1 1.3 25 5.5 0.0 6.6 6 0 0 6 6 5 0 HEAT-like repeat HEAT PF02985.22 KFQ99824.1 - 4.1e-06 26.6 23.7 0.58 10.6 0.1 9.3 10 0 0 10 10 8 2 HEAT repeat CLASP_N PF12348.8 KFQ99824.1 - 0.00037 20.1 12.3 0.016 14.8 0.4 4.4 4 1 1 5 5 5 2 CLASP N terminal IFRD PF05004.13 KFQ99824.1 - 0.0019 17.4 0.3 0.0019 17.4 0.3 3.9 4 2 0 4 4 4 1 Interferon-related developmental regulator (IFRD) Tti2 PF10521.9 KFQ99824.1 - 0.0085 15.7 5.9 1.7 8.1 0.1 4.8 3 1 0 3 3 3 1 Tti2 family UME PF08064.13 KFQ99824.1 - 0.056 13.3 11.4 0.29 11.1 2.1 3.7 4 2 1 5 5 5 0 UME (NUC010) domain Prok_Ub PF14454.6 KFQ99824.1 - 0.057 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic Ubiquitin Telomere_reg-2 PF10193.9 KFQ99824.1 - 0.06 13.8 6.8 0.061 13.8 1.5 3.5 3 0 0 3 3 3 0 Telomere length regulation protein STAR_dimer PF16544.5 KFQ99824.1 - 0.062 12.9 0.0 24 4.6 0.0 3.2 2 0 0 2 2 2 0 Homodimerisation region of STAR domain protein DUF2201_N PF13203.6 KFQ99824.1 - 0.18 11.4 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain RTP1_C1 PF10363.9 KFQ99824.1 - 0.54 10.5 9.2 9.8 6.4 0.1 4.6 4 2 3 7 7 7 0 Required for nuclear transport of RNA pol II C-terminus 1 NUC173 PF08161.12 KFQ99824.1 - 0.82 9.3 7.2 26 4.4 0.2 4.4 4 2 1 5 5 5 0 NUC173 domain MMS19_N PF14500.6 KFQ99824.1 - 1.1 8.8 11.3 36 3.8 0.2 4.8 3 2 1 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II Sad1_UNC PF07738.13 KFQ99825.1 - 8.6e-44 148.7 0.0 1.8e-43 147.7 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal MRP PF09387.10 KFQ99825.1 - 3.6e-37 128.3 0.6 6.5e-37 127.4 0.6 1.4 1 0 0 1 1 1 1 Mitochondrial RNA binding protein MRP Sun2_CC2 PF18580.1 KFQ99825.1 - 7.1e-11 42.2 2.4 2.1e-10 40.6 2.4 1.9 1 0 0 1 1 1 1 SUN2 coiled coil domain 2 SlyX PF04102.12 KFQ99825.1 - 1.3 9.7 4.9 2 9.1 0.7 3.2 2 1 0 2 2 2 0 SlyX DUF410 PF04190.13 KFQ99826.1 - 2.7e-66 224.0 0.1 1.6e-64 218.2 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF410) SDH_C PF18317.1 KFQ99826.1 - 0.27 11.0 1.0 1.3 8.9 0.9 2.2 2 0 0 2 2 2 0 Shikimate 5'-dehydrogenase C-terminal domain ArfGap PF01412.18 KFQ99827.1 - 7e-28 97.1 0.1 1.2e-27 96.3 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 KFQ99827.1 - 2.3e-22 79.5 0.2 1.5e-12 48.0 0.1 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KFQ99827.1 - 1.6e-08 34.9 1.5 4e-05 24.0 0.3 3.4 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 KFQ99827.1 - 6.3e-05 23.2 3.7 0.078 13.3 0.1 3.0 3 1 0 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.6 KFQ99827.1 - 0.0011 19.0 0.2 0.19 11.8 0.0 2.8 3 0 0 3 3 3 1 PH domain p450 PF00067.22 KFQ99828.1 - 7.6e-122 407.4 0.7 8.4e-122 407.2 0.7 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFQ99829.1 - 3.1e-115 385.6 0.9 3.4e-115 385.4 0.9 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3865 PF12981.7 KFQ99829.1 - 0.13 12.2 0.2 0.27 11.1 0.2 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) p450 PF00067.22 KFQ99830.1 - 2.4e-121 405.7 1.0 2.6e-121 405.6 1.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2373 PF10180.9 KFQ99831.1 - 2.4e-25 88.2 0.7 5.2e-25 87.1 0.7 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) 7tm_1 PF00001.21 KFQ99832.1 - 5.1e-13 48.9 17.1 7.9e-13 48.3 17.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Sid-5 PF17204.3 KFQ99832.1 - 0.49 10.6 0.1 0.49 10.6 0.1 2.7 3 1 0 3 3 3 0 Sid-5 family Col_cuticle_N PF01484.17 KFQ99832.1 - 1.1 9.4 0.1 1.1 9.4 0.1 3.0 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain SieB PF14163.6 KFQ99833.1 - 4.8 6.7 12.5 0.56 9.7 0.8 3.2 3 1 0 3 3 3 0 Super-infection exclusion protein B 7tm_1 PF00001.21 KFQ99834.1 - 2.3e-41 141.9 16.8 2.9e-41 141.5 16.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ99834.1 - 3.2e-05 23.4 16.1 4.2e-05 23.0 16.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Abhydrolase_9_N PF15420.6 KFQ99834.1 - 0.64 10.0 3.1 1.1 9.2 3.1 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus PHO4 PF01384.20 KFQ99834.1 - 2.5 7.1 6.4 1 8.3 4.3 1.5 1 1 1 2 2 2 0 Phosphate transporter family zf-AN1 PF01428.16 KFQ99835.1 - 2.7e-23 81.8 31.2 1.1e-12 47.9 9.2 2.7 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 KFQ99835.1 - 0.082 13.3 21.1 0.12 12.8 4.9 2.7 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain IBR PF01485.21 KFQ99835.1 - 0.13 12.5 26.7 0.78 10.0 14.5 3.6 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-C2H2_4 PF13894.6 KFQ99835.1 - 0.64 11.0 12.3 11 7.2 0.7 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger zinc_ribbon_4 PF13717.6 KFQ99835.1 - 2.9 7.9 13.6 1.7 8.6 0.7 3.7 4 0 0 4 4 4 0 zinc-ribbon domain DUF3585 PF12130.8 KFQ99836.1 - 5.9e-41 139.8 23.9 9.8e-41 139.1 23.9 1.4 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain CH PF00307.31 KFQ99836.1 - 2.2e-23 82.5 0.0 4.7e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFQ99836.1 - 1.2e-08 34.6 0.0 2.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain LIM PF00412.22 KFQ99836.1 - 1.9e-05 24.8 2.4 4.1e-05 23.7 2.4 1.6 1 0 0 1 1 1 1 LIM domain Pox_A_type_inc PF04508.12 KFQ99836.1 - 2.8 7.9 5.5 8.4 6.4 1.6 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF3677 PF12432.8 KFQ99837.1 - 6.2e-32 109.8 9.8 7.5e-32 109.5 3.9 3.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3677) UNC45-central PF11701.8 KFQ99837.1 - 0.026 14.5 5.7 0.25 11.3 0.1 4.9 4 1 1 5 5 5 0 Myosin-binding striated muscle assembly central Glyco_hydro_31 PF01055.26 KFQ99838.1 - 2.8e-137 458.5 0.0 3.3e-137 458.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KFQ99838.1 - 9.2e-12 45.2 0.1 1.5e-11 44.5 0.1 1.3 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KFQ99838.1 - 3.2e-10 40.2 0.1 1.4e-09 38.2 0.1 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 KFQ99838.1 - 0.17 12.2 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) bZIP_Maf PF03131.17 KFQ99839.1 - 1.6e-34 118.3 12.5 1.9e-34 118.0 12.5 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor DivIC PF04977.15 KFQ99839.1 - 0.00011 21.9 5.0 0.00011 21.9 5.0 2.1 1 1 1 2 2 2 1 Septum formation initiator bZIP_1 PF00170.21 KFQ99839.1 - 0.0002 21.4 16.6 0.0046 17.0 16.6 2.4 1 1 0 1 1 1 1 bZIP transcription factor Cnn_1N PF07989.11 KFQ99839.1 - 0.003 17.7 7.8 0.0074 16.4 7.7 1.8 1 1 0 1 1 1 1 Centrosomin N-terminal motif 1 DUF1192 PF06698.11 KFQ99839.1 - 0.0054 16.8 6.2 0.043 13.9 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) Prominin PF05478.11 KFQ99839.1 - 0.013 13.5 1.2 0.016 13.2 1.2 1.0 1 0 0 1 1 1 0 Prominin Spc24 PF08286.11 KFQ99839.1 - 0.033 14.4 1.4 0.06 13.6 0.2 1.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 bZIP_2 PF07716.15 KFQ99839.1 - 0.035 14.2 11.5 0.035 14.2 11.5 2.5 1 1 2 3 3 3 0 Basic region leucine zipper FapA PF03961.13 KFQ99839.1 - 0.087 11.4 2.5 0.092 11.3 2.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DASH_Spc19 PF08287.11 KFQ99839.1 - 0.25 11.2 10.1 0.35 10.7 10.1 1.2 1 0 0 1 1 1 0 Spc19 DUF4164 PF13747.6 KFQ99839.1 - 0.28 11.5 8.3 0.66 10.3 8.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) GIT_CC PF16559.5 KFQ99839.1 - 0.3 11.0 4.6 0.16 11.8 1.7 2.1 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Mst1_SARAH PF11629.8 KFQ99839.1 - 0.34 11.0 6.3 7.6 6.7 2.0 2.6 2 1 0 2 2 2 0 C terminal SARAH domain of Mst1 YabA PF06156.13 KFQ99839.1 - 0.36 11.5 6.9 0.16 12.7 2.5 2.0 1 1 1 2 2 2 0 Initiation control protein YabA Nup54 PF13874.6 KFQ99839.1 - 1.1 9.3 8.6 1.9 8.6 8.6 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Spc7 PF08317.11 KFQ99839.1 - 1.4 7.7 9.5 2.3 7.0 9.5 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein ZapB PF06005.12 KFQ99839.1 - 2.2 8.8 13.5 4.2 7.9 7.8 2.4 1 1 1 2 2 2 0 Cell division protein ZapB DUF2205 PF10224.9 KFQ99839.1 - 2.8 8.0 8.2 0.83 9.7 3.1 2.2 1 1 1 2 2 2 0 Short coiled-coil protein XkdW PF09636.10 KFQ99839.1 - 8.5 6.5 6.4 6.2 7.0 2.4 2.1 1 1 1 2 2 2 0 XkdW protein APG6_N PF17675.1 KFQ99839.1 - 8.9 6.8 12.9 27 5.3 12.9 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region Solute_trans_a PF03619.16 KFQ99840.1 - 2.6e-93 312.4 22.3 3.2e-93 312.1 22.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha PAC3 PF10178.9 KFQ99841.1 - 2.2e-28 98.2 0.0 2.9e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 LRR_8 PF13855.6 KFQ99842.1 - 8.3e-24 83.1 11.5 7.3e-13 48.1 0.3 3.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFQ99842.1 - 4.9e-10 39.5 11.2 0.00034 21.0 0.4 3.7 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFQ99842.1 - 1.2e-08 35.0 0.4 2.6e-08 33.9 0.4 1.6 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFQ99842.1 - 0.00076 19.0 3.3 0.017 14.6 0.3 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFQ99842.1 - 0.00096 19.4 5.8 25 5.9 0.0 5.3 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.6 KFQ99842.1 - 0.066 13.3 7.9 5.7 7.3 0.1 4.6 4 0 0 4 4 4 0 Leucine Rich repeat MAD PF05557.13 KFQ99844.1 - 4.1e-194 646.7 100.2 5.1e-194 646.4 100.2 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein TSC22 PF01166.18 KFQ99844.1 - 1.8e-05 24.9 4.8 1.8e-05 24.9 4.8 9.6 7 2 2 9 9 9 1 TSC-22/dip/bun family DUF4200 PF13863.6 KFQ99844.1 - 0.0033 17.8 9.6 0.0033 17.8 9.6 7.3 4 2 2 6 6 6 1 Domain of unknown function (DUF4200) ATG16 PF08614.11 KFQ99844.1 - 0.01 16.1 19.3 0.01 16.1 19.3 5.7 2 1 2 5 5 5 0 Autophagy protein 16 (ATG16) FtsJ PF01728.19 KFQ99845.1 - 3.4e-51 173.9 0.0 4e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 KFQ99845.1 - 0.0081 16.0 0.0 2.4 7.9 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KFQ99845.1 - 0.023 14.5 0.0 0.078 12.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain NUDIX PF00293.28 KFQ99846.1 - 3.9e-15 56.1 0.1 5e-15 55.7 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain PX PF00787.24 KFQ99848.1 - 1.3e-21 76.6 2.3 1.3e-21 76.6 2.3 2.0 2 1 0 2 2 2 1 PX domain Perilipin PF03036.16 KFQ99848.1 - 0.0013 17.8 2.8 0.0085 15.2 2.6 2.0 2 0 0 2 2 2 1 Perilipin family EPSP_synthase PF00275.20 KFQ99848.1 - 0.093 11.4 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) eIF2A PF08662.11 KFQ99849.1 - 4.9e-72 241.9 7.5 2.7e-66 223.1 2.4 4.1 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KFQ99849.1 - 6.4e-07 29.1 0.1 1.5e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC4_WD40 PF12894.7 KFQ99849.1 - 4.2e-06 27.0 2.1 0.4 11.0 0.0 6.0 4 2 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Methyltr_RsmF_N PF17125.5 KFQ99849.1 - 0.048 14.2 0.6 2.3 8.8 0.0 3.5 3 1 1 4 4 4 0 N-terminal domain of 16S rRNA methyltransferase RsmF Nup35_RRM PF05172.13 KFQ99849.1 - 0.095 12.7 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF4060 PF13269.6 KFQ99849.1 - 0.15 12.2 0.1 0.69 10.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4060) PD40 PF07676.12 KFQ99849.1 - 0.21 11.6 4.6 66 3.6 0.1 4.9 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 KFQ99849.1 - 0.35 11.8 5.6 3.1e+02 2.5 0.0 6.2 6 1 1 7 7 7 0 WD domain, G-beta repeat Sulfotransfer_2 PF03567.14 KFQ99850.1 - 2.6e-64 217.6 3.3 2.6e-64 217.6 1.5 1.7 2 0 0 2 2 2 1 Sulfotransferase family FRB_dom PF08771.11 KFQ99850.1 - 0.042 14.3 0.3 6.5 7.2 0.1 2.6 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain 7tm_1 PF00001.21 KFQ99851.1 - 3.4e-44 151.1 16.9 3.9e-44 151.0 16.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFQ99851.1 - 4.9e-06 26.4 17.9 2.5e-05 24.0 17.9 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFQ99851.1 - 0.00028 20.7 7.8 0.00045 20.0 7.8 1.5 1 1 0 1 1 1 1 Olfactory receptor Serpentine_r_xa PF03383.15 KFQ99851.1 - 0.01 15.8 2.7 0.01 15.8 2.7 2.1 1 1 1 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa DUF2434 PF10361.9 KFQ99851.1 - 0.11 11.5 9.6 0.84 8.6 1.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2434) DUF4212 PF13937.6 KFQ99851.1 - 0.14 12.5 2.4 2.9 8.3 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) Git3 PF11710.8 KFQ99851.1 - 5.7 6.7 13.2 0.39 10.4 8.0 1.7 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 Gal-bind_lectin PF00337.22 KFQ99852.1 - 9.2e-36 122.3 0.1 1e-35 122.2 0.1 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin Fringe PF02434.16 KFQ99853.1 - 1.8e-126 420.7 0.1 2.1e-126 420.5 0.1 1.0 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 KFQ99853.1 - 0.00015 21.7 0.0 0.00039 20.3 0.0 1.7 1 1 0 1 1 1 1 Galactosyltransferase Glyco_tranf_2_4 PF13704.6 KFQ99853.1 - 0.11 13.1 0.2 0.19 12.3 0.2 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Tweety PF04906.13 KFQ99854.1 - 5.6e-169 562.1 11.1 7e-169 561.8 11.1 1.0 1 0 0 1 1 1 1 Tweety DUF4131 PF13567.6 KFQ99854.1 - 0.0036 17.0 0.3 0.0036 17.0 0.3 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4131) DUF2721 PF11026.8 KFQ99854.1 - 0.0048 16.8 0.3 0.0048 16.8 0.3 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2721) Pex24p PF06398.11 KFQ99854.1 - 0.13 11.2 0.0 0.85 8.5 0.0 2.2 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin Prominin PF05478.11 KFQ99854.1 - 0.19 9.6 7.6 0.085 10.8 0.3 2.7 2 1 0 3 3 3 0 Prominin DUF3413 PF11893.8 KFQ99854.1 - 6.1 5.9 8.2 0.28 10.3 2.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) MgtE PF01769.16 KFQ99854.1 - 6.4 7.2 8.8 4 7.8 0.5 2.8 3 0 0 3 3 3 0 Divalent cation transporter SlyX PF04102.12 KFQ99855.1 - 0.00047 20.7 13.9 0.0088 16.6 0.3 3.7 2 1 0 3 3 3 2 SlyX SOGA PF11365.8 KFQ99855.1 - 0.006 17.7 10.7 0.006 17.7 10.7 3.1 3 1 0 3 3 2 1 Protein SOGA Cnn_1N PF07989.11 KFQ99855.1 - 0.023 14.8 0.4 0.023 14.8 0.4 3.6 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 YabA PF06156.13 KFQ99855.1 - 0.038 14.6 22.8 0.2 12.3 2.4 3.4 2 1 1 3 3 3 0 Initiation control protein YabA ATG16 PF08614.11 KFQ99855.1 - 0.09 13.0 26.4 0.64 10.2 3.7 3.5 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) adh_short PF00106.25 KFQ99855.1 - 0.18 11.3 0.6 0.44 10.0 0.6 1.7 1 1 1 2 2 2 0 short chain dehydrogenase PCRF PF03462.18 KFQ99855.1 - 0.19 11.6 14.1 0.26 11.1 0.4 2.3 2 0 0 2 2 2 0 PCRF domain Allexi_40kDa PF05549.11 KFQ99855.1 - 0.24 10.9 9.1 0.03 13.8 4.3 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein DivIC PF04977.15 KFQ99855.1 - 0.26 11.1 22.1 0.61 9.9 0.7 3.7 2 1 1 3 3 3 0 Septum formation initiator Fib_alpha PF08702.10 KFQ99855.1 - 0.65 10.2 18.4 3 8.0 0.8 3.5 1 1 0 3 3 3 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 KFQ99855.1 - 0.87 10.1 28.7 1 9.9 7.4 3.1 1 1 2 3 3 3 0 Apg6 coiled-coil region Chibby PF14645.6 KFQ99855.1 - 1.4 9.3 19.1 0.5 10.8 6.1 2.8 2 1 0 2 2 2 0 Chibby family Lebercilin PF15619.6 KFQ99855.1 - 1.5 8.5 27.8 15 5.2 16.1 2.5 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CpxA_peri PF16527.5 KFQ99855.1 - 1.7 9.0 12.1 1.8 8.9 2.5 2.6 1 1 0 2 2 2 0 Two-component sensor protein CpxA, periplasmic domain Seryl_tRNA_N PF02403.22 KFQ99855.1 - 4.1 7.7 23.4 3.3 8.0 3.8 3.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 KFQ99855.1 - 9.2 5.5 14.7 73 2.6 14.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HEAT PF02985.22 KFQ99856.1 - 1e-09 37.8 7.6 0.0081 16.3 0.0 7.1 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.6 KFQ99856.1 - 1.2e-06 28.8 0.0 0.0017 18.7 0.0 4.0 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 KFQ99856.1 - 0.00014 22.3 1.1 0.32 11.6 0.0 4.7 4 1 1 5 5 5 2 HEAT-like repeat RTP1_C1 PF10363.9 KFQ99856.1 - 0.0065 16.6 0.0 0.04 14.1 0.0 2.4 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_N PF14500.6 KFQ99856.1 - 0.035 13.7 2.2 3.4 7.2 0.5 2.8 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Peptidase_M54 PF07998.11 KFQ99857.1 - 6.8e-05 22.9 1.3 0.00089 19.3 3.3 1.8 2 0 0 2 2 2 1 Peptidase family M54 DUF4241 PF14025.6 KFQ99857.1 - 0.13 12.5 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) Peptidase_M10 PF00413.24 KFQ99857.1 - 0.18 11.6 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Matrixin G-alpha PF00503.20 KFQ99858.1 - 9.7e-81 271.7 3.2 1.1e-80 271.5 3.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFQ99858.1 - 1.2e-10 41.2 1.1 7.6e-10 38.5 0.4 2.2 1 1 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFQ99858.1 - 0.12 11.9 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain CARD PF00619.21 KFQ99859.1 - 6.5e-22 77.4 0.0 2.7e-21 75.4 0.0 2.2 1 0 0 1 1 1 1 Caspase recruitment domain PDZ PF00595.24 KFQ99859.1 - 1.1e-05 25.7 0.0 2.3e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Guanylate_kin PF00625.21 KFQ99859.1 - 4.4e-05 23.2 7.0 4.5e-05 23.2 0.1 2.6 2 0 0 2 2 2 1 Guanylate kinase PDZ_6 PF17820.1 KFQ99859.1 - 0.00086 19.1 0.0 0.0025 17.6 0.0 1.8 1 0 0 1 1 1 1 PDZ domain ERM PF00769.19 KFQ99859.1 - 4.3 7.1 47.4 1.7 8.4 15.0 3.6 2 1 1 3 3 3 0 Ezrin/radixin/moesin family fn3 PF00041.21 KFQ99860.1 - 4.4e-172 558.9 47.3 2.5e-16 59.8 0.1 14.0 13 1 0 13 13 13 13 Fibronectin type III domain Ig_3 PF13927.6 KFQ99860.1 - 1.4e-73 243.5 0.9 5.1e-15 55.8 0.0 7.3 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 KFQ99860.1 - 4e-68 225.5 0.0 2.8e-16 59.4 0.0 7.3 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.6 KFQ99860.1 - 6.7e-50 167.4 0.1 4.4e-09 36.5 0.0 6.9 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.25 KFQ99860.1 - 6.6e-38 128.8 0.0 6.3e-09 35.9 0.0 7.0 6 0 0 6 6 6 6 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFQ99860.1 - 1.3e-26 92.9 29.6 0.00049 20.6 0.2 13.6 13 1 0 13 13 13 7 Purple acid Phosphatase, N-terminal domain V-set PF07686.17 KFQ99860.1 - 2e-14 53.7 15.9 0.039 14.1 0.1 11.6 8 5 3 11 11 11 4 Immunoglobulin V-set domain Ig_6 PF18452.1 KFQ99860.1 - 2e-09 36.9 0.3 0.23 11.0 0.1 6.0 7 0 0 7 7 7 3 Immunoglobulin domain Ig_5 PF16681.5 KFQ99860.1 - 6e-09 36.2 0.0 0.16 12.4 0.0 6.5 6 1 0 6 6 6 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KFQ99860.1 - 3.9e-08 33.2 0.5 0.39 10.8 0.0 5.6 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Interfer-bind PF09294.10 KFQ99860.1 - 4.7e-08 33.3 0.1 5 7.5 0.0 8.1 10 0 0 10 10 10 2 Interferon-alpha/beta receptor, fibronectin type III C1-set PF07654.15 KFQ99860.1 - 4.7e-07 30.1 0.1 1.4 9.3 0.0 5.4 5 0 0 5 5 5 2 Immunoglobulin C1-set domain Tissue_fac PF01108.17 KFQ99860.1 - 7.9e-07 28.9 4.4 0.18 11.6 0.0 7.2 7 0 0 7 7 7 1 Tissue factor DUF2369 PF10179.9 KFQ99860.1 - 0.00019 21.7 1.3 1.5 9.2 0.0 6.9 10 0 0 10 10 8 1 Uncharacterised conserved protein (DUF2369) fn3_4 PF16794.5 KFQ99860.1 - 0.00031 20.6 0.1 2.6 8.0 0.0 5.5 5 0 0 5 5 5 1 Fibronectin-III type domain GPI-anchored PF10342.9 KFQ99860.1 - 0.00079 20.1 4.1 0.89 10.4 0.0 6.5 6 1 1 7 7 5 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family HPP PF04982.13 KFQ99860.1 - 0.019 15.1 0.1 0.64 10.2 0.0 3.3 3 0 0 3 3 3 0 HPP family p450 PF00067.22 KFQ99861.1 - 1.5e-113 380.0 0.0 1.7e-113 379.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M48 PF01435.18 KFQ99861.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M48 p450 PF00067.22 KFQ99862.1 - 1.7e-126 422.7 0.2 1.9e-126 422.5 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Forkhead PF00250.18 KFQ99864.1 - 1.1e-41 141.0 0.2 1.7e-41 140.3 0.2 1.3 1 0 0 1 1 1 1 Forkhead domain SPG48 PF14764.6 KFQ99865.1 - 3.1e-44 150.2 11.3 3.6e-44 150.0 3.6 3.7 4 0 0 4 4 4 1 AP-5 complex subunit, vesicle trafficking HlyIII PF03006.20 KFQ99866.1 - 1e-18 67.9 19.1 1.3e-18 67.5 19.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related WD40 PF00400.32 KFQ99867.1 - 3.6e-05 24.5 0.0 4 8.5 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ99867.1 - 0.0015 18.7 0.0 0.17 12.2 0.0 3.3 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFQ99867.1 - 0.063 12.2 0.2 5.6 5.8 0.0 2.3 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 KFQ99867.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain Nucleoside_tran PF01733.18 KFQ99868.1 - 1.9e-51 175.3 1.0 6.7e-51 173.5 1.0 1.8 1 1 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.16 KFQ99868.1 - 0.18 10.7 28.2 0.032 13.2 9.8 2.8 1 1 0 2 2 2 0 Major Facilitator Superfamily F-box PF00646.33 KFQ99869.1 - 6.6e-07 29.0 1.6 6.6e-07 29.0 1.6 2.6 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KFQ99869.1 - 1.9e-06 27.6 1.3 1.9e-06 27.6 1.3 2.5 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 KFQ99869.1 - 0.00024 21.4 16.4 0.024 15.1 0.4 6.0 5 2 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFQ99869.1 - 0.00079 19.3 12.1 3.2 8.0 0.4 6.6 6 0 0 6 6 6 1 Leucine Rich repeat LRR_8 PF13855.6 KFQ99869.1 - 3.1 7.6 12.9 3.3 7.6 0.5 5.0 5 1 1 6 6 6 0 Leucine rich repeat LRR_1 PF00560.33 KFQ99869.1 - 4.6 8.2 16.7 18 6.3 0.6 6.3 5 1 0 5 5 5 0 Leucine Rich Repeat Actin PF00022.19 KFQ99870.1 - 1.3e-151 504.9 0.0 4.1e-151 503.2 0.0 1.6 1 1 0 1 1 1 1 Actin Fascin PF06268.13 KFQ99872.1 - 3.8e-98 323.3 0.6 4.6e-31 107.3 0.7 4.0 4 0 0 4 4 4 4 Fascin domain FRG1 PF06229.12 KFQ99872.1 - 1.5e-18 67.2 0.4 0.00044 20.0 0.0 6.2 2 2 5 7 7 7 6 FRG1-like domain FGF PF00167.18 KFQ99872.1 - 0.024 14.7 0.0 10 6.3 0.1 3.1 2 2 0 2 2 2 0 Fibroblast growth factor Arm PF00514.23 KFQ99873.1 - 2.2e-75 246.7 19.3 7.3e-12 44.9 0.2 9.1 9 1 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KFQ99873.1 - 5e-22 78.1 6.5 1e-21 77.1 6.5 1.6 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 KFQ99873.1 - 5.7e-19 67.4 1.4 8.1e-19 66.9 0.3 1.9 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 KFQ99873.1 - 6.5e-19 68.0 3.6 2.9e-06 27.6 0.0 6.5 3 2 4 7 7 7 5 HEAT-like repeat HEAT_2 PF13646.6 KFQ99873.1 - 5.5e-13 49.1 1.0 0.00045 20.6 0.0 5.8 3 2 4 7 7 7 4 HEAT repeats HEAT PF02985.22 KFQ99873.1 - 2.7e-09 36.5 0.7 0.076 13.3 0.0 6.5 6 0 0 6 6 6 2 HEAT repeat V-ATPase_H_C PF11698.8 KFQ99873.1 - 2.7e-05 24.2 1.8 0.27 11.4 0.2 3.9 4 1 0 4 4 4 2 V-ATPase subunit H WD40 PF00400.32 KFQ99874.1 - 1.5e-12 47.8 15.8 0.00015 22.5 0.5 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ99874.1 - 2.5e-11 43.7 0.7 0.026 14.8 0.0 3.7 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain LytB_WW PF18342.1 KFQ99874.1 - 0.057 13.6 1.1 0.3 11.2 0.2 2.3 2 0 0 2 2 2 0 Endo-beta-N-acetylglucosaminidase LytB WW domain WD40 PF00400.32 KFQ99875.1 - 8.8e-13 48.5 17.8 3.3e-05 24.5 0.2 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFQ99875.1 - 2.3e-12 47.0 0.8 0.0017 18.6 0.0 4.1 1 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFQ99875.1 - 0.00011 22.1 0.4 0.13 12.1 0.1 2.9 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PP28 PF10252.9 KFQ99876.1 - 3.1e-30 104.5 16.0 3.1e-30 104.5 16.0 2.5 2 1 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 RPN2_C PF18004.1 KFQ99876.1 - 0.006 16.5 7.8 0.006 16.5 7.8 2.3 1 1 1 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain Nop53 PF07767.11 KFQ99876.1 - 4.1 6.7 33.4 4.8 6.5 33.4 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) G10 PF01125.17 KFQ99877.1 - 3.5e-67 224.7 5.2 3.8e-67 224.6 5.2 1.0 1 0 0 1 1 1 1 G10 protein PPR_2 PF13041.6 KFQ99878.1 - 2.3e-45 152.6 2.1 1.5e-14 53.9 0.0 8.1 5 2 3 8 8 8 8 PPR repeat family PPR_3 PF13812.6 KFQ99878.1 - 1.2e-36 124.6 0.6 4.2e-07 29.9 0.1 6.2 6 0 0 6 6 6 6 Pentatricopeptide repeat domain PPR_long PF17177.4 KFQ99878.1 - 2.5e-20 72.8 0.0 1.7e-13 50.4 0.0 4.1 2 1 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KFQ99878.1 - 6.4e-18 63.7 7.9 8.2e-07 28.9 0.1 8.0 8 0 0 8 8 8 3 PPR repeat PPR_1 PF12854.7 KFQ99878.1 - 1.8e-11 43.5 2.2 0.0011 18.7 0.1 7.1 9 0 0 9 9 9 2 PPR repeat MNE1 PF13762.6 KFQ99878.1 - 0.026 14.5 1.8 5 7.1 0.1 3.6 3 1 0 4 4 4 0 Mitochondrial splicing apparatus component DUF3384 PF11864.8 KFQ99878.1 - 0.041 12.8 0.0 0.091 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) WRW PF10206.9 KFQ99879.1 - 1.8e-14 53.9 0.0 2.3e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f IRK_C PF17655.1 KFQ99880.1 - 8.1e-78 260.0 0.0 1.1e-77 259.6 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFQ99880.1 - 6.7e-66 220.5 1.4 9.3e-66 220.0 1.4 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain IRK_N PF08466.10 KFQ99880.1 - 2.1e-24 85.4 0.2 3.6e-24 84.7 0.2 1.4 1 0 0 1 1 1 1 Inward rectifier potassium channel N-terminal Ion_trans_2 PF07885.16 KFQ99880.1 - 0.043 13.8 6.6 0.12 12.4 6.6 1.8 1 1 0 1 1 1 0 Ion channel Pkinase PF00069.25 KFQ99882.1 - 2.5e-56 191.0 0.0 3e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ99882.1 - 1.3e-38 132.8 0.0 1.6e-38 132.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFQ99882.1 - 1.4e-05 24.6 0.0 2.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFQ99882.1 - 0.0016 17.4 0.0 0.0029 16.6 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KFQ99882.1 - 0.0034 16.5 0.2 0.0054 15.8 0.2 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 KFQ99882.1 - 0.009 14.8 0.1 0.021 13.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFQ99882.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFQ99882.1 - 0.021 14.4 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF4344 PF14247.6 KFQ99882.1 - 0.033 13.9 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase DHR-2 PF06920.13 KFQ99882.1 - 0.089 11.4 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Dock homology region 2 RIO1 PF01163.22 KFQ99882.1 - 0.097 12.3 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Acetyltransf_CG PF14542.6 KFQ99883.1 - 1.4e-22 79.6 0.2 1.7e-22 79.3 0.2 1.0 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 KFQ99883.1 - 0.0026 18.0 0.0 0.0028 17.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFQ99883.1 - 0.017 15.1 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3222 PF11519.8 KFQ99883.1 - 0.074 13.3 0.0 0.099 12.9 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3222) Acetyltransf_7 PF13508.7 KFQ99883.1 - 0.079 13.4 0.1 0.1 13.0 0.1 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Mito_morph_reg PF14972.6 KFQ99884.1 - 7.5e-78 259.7 0.7 8.4e-78 259.5 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial morphogenesis regulator adh_short PF00106.25 KFQ99885.1 - 1.1e-52 178.4 0.3 1.5e-52 177.9 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFQ99885.1 - 1.1e-37 129.8 0.6 1.4e-37 129.5 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFQ99885.1 - 6.6e-12 45.7 0.1 9.6e-12 45.2 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFQ99885.1 - 2.9e-06 26.9 0.0 4.2e-05 23.1 0.0 2.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 KFQ99885.1 - 0.00044 19.5 0.1 0.00074 18.7 0.1 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.15 KFQ99885.1 - 0.0007 19.8 0.1 0.0017 18.6 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KFQ99885.1 - 0.0044 17.1 0.4 0.027 14.5 0.1 2.4 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 KFQ99885.1 - 0.02 14.2 0.5 1.4 8.2 0.0 2.6 2 1 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 KFQ99885.1 - 0.035 13.6 0.3 0.17 11.4 0.3 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HEPN PF05168.14 KFQ99885.1 - 0.16 12.1 0.0 1.7 8.8 0.0 2.4 2 1 0 3 3 3 0 HEPN domain UCH PF00443.29 KFQ99886.1 - 9.5e-58 195.7 0.1 1.2e-57 195.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFQ99886.1 - 8.6e-25 88.0 2.8 3.5e-24 86.0 2.8 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFQ99886.1 - 6.3e-14 52.0 10.7 6.3e-14 52.0 10.7 2.3 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_C98 PF15499.6 KFQ99886.1 - 3.5e-05 23.4 3.3 0.011 15.3 0.1 3.3 3 0 0 3 3 3 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase ISG65-75 PF11727.8 KFQ99886.1 - 0.3 10.3 4.6 0.055 12.7 0.7 1.7 2 0 0 2 2 2 0 Invariant surface glycoprotein zf-RING_13 PF17977.1 KFQ99886.1 - 0.92 9.7 7.6 4.1 7.6 7.6 2.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TACI-CRD2 PF09305.10 KFQ99887.1 - 2e-23 82.1 22.5 5.5e-21 74.3 7.6 3.5 3 0 0 3 3 3 2 TACI, cysteine-rich domain BCMA-Tall_bind PF09257.10 KFQ99887.1 - 0.00037 20.5 17.2 0.0038 17.3 6.9 3.2 3 0 0 3 3 3 2 BCMA, TALL-1 binding PH PF00169.29 KFQ99888.1 - 3.3e-19 69.3 0.9 1.8e-16 60.6 0.4 2.6 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KFQ99888.1 - 0.003 17.9 8.8 0.013 15.9 3.3 3.7 3 1 0 3 3 3 1 Pleckstrin homology domain OmpH PF03938.14 KFQ99888.1 - 0.0061 16.9 12.0 0.0061 16.9 12.0 4.5 3 1 2 5 5 5 2 Outer membrane protein (OmpH-like) Baculo_PEP_C PF04513.12 KFQ99888.1 - 9.2 6.3 14.3 1.2 9.1 7.1 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Folliculin_C PF16692.5 KFQ99889.1 - 5.3e-91 304.3 0.1 9.4e-91 303.5 0.1 1.4 1 0 0 1 1 1 1 Folliculin C-terminal domain Folliculin PF11704.8 KFQ99889.1 - 1.2e-51 175.2 0.0 2.2e-51 174.4 0.0 1.4 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport DUF5357 PF17310.2 KFQ99889.1 - 0.031 12.9 0.0 0.048 12.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5357) PCI PF01399.27 KFQ99890.1 - 1.3e-19 70.7 1.0 5.1e-19 68.7 0.2 2.3 2 0 0 2 2 2 1 PCI domain RasGEF PF00617.19 KFQ99890.1 - 0.0052 17.0 0.9 0.49 10.6 0.1 2.9 3 0 0 3 3 3 1 RasGEF domain TPR_1 PF00515.28 KFQ99890.1 - 0.0077 16.0 2.5 0.017 15.0 0.9 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFQ99890.1 - 0.045 14.0 2.1 1.4 9.3 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat MAS20 PF02064.15 KFQ99890.1 - 0.05 13.7 0.2 0.31 11.1 0.1 2.2 2 0 0 2 2 2 0 MAS20 protein import receptor Sel1 PF08238.12 KFQ99890.1 - 0.066 13.9 1.0 0.17 12.6 1.0 1.8 1 0 0 1 1 1 0 Sel1 repeat TPR_10 PF13374.6 KFQ99890.1 - 0.067 13.1 0.3 1.1 9.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFQ99890.1 - 0.073 13.2 2.3 0.16 12.2 0.9 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFQ99890.1 - 0.11 12.9 0.1 2.5 8.4 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat NT5C PF06941.12 KFQ99891.1 - 3.8e-26 92.1 0.0 4.3e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Med9 PF07544.13 KFQ99892.1 - 9.3e-20 70.5 4.0 1e-19 70.4 4.0 1.0 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.8 KFQ99892.1 - 1.5e-08 35.0 2.4 1.8e-08 34.8 2.4 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex APG17 PF04108.12 KFQ99892.1 - 0.0025 17.0 0.3 0.0027 16.9 0.3 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 PHA_synth_III_E PF09712.10 KFQ99892.1 - 0.0028 16.8 0.6 0.003 16.7 0.6 1.1 1 0 0 1 1 1 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) HSBP1 PF06825.12 KFQ99892.1 - 0.015 15.2 0.7 0.015 15.2 0.7 1.8 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DASH_Duo1 PF08651.10 KFQ99892.1 - 0.016 15.0 0.3 0.024 14.4 0.3 1.3 1 0 0 1 1 1 0 DASH complex subunit Duo1 4HB_MCP_1 PF12729.7 KFQ99892.1 - 0.02 14.5 0.2 0.022 14.3 0.2 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction ELK PF03789.13 KFQ99892.1 - 0.027 14.6 1.8 0.13 12.4 0.5 2.3 2 0 0 2 2 2 0 ELK domain GrpE PF01025.19 KFQ99892.1 - 0.039 13.6 0.6 0.041 13.5 0.6 1.1 1 0 0 1 1 1 0 GrpE FapA PF03961.13 KFQ99892.1 - 0.054 12.1 2.3 0.062 11.9 2.3 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A XPC-binding PF09280.11 KFQ99892.1 - 0.076 12.8 7.1 4.5 7.1 3.9 2.5 2 1 0 2 2 2 0 XPC-binding domain DUF3452 PF11934.8 KFQ99892.1 - 0.078 12.5 0.8 0.11 12.1 0.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) Enkurin PF13864.6 KFQ99892.1 - 0.16 12.5 5.3 0.53 10.8 0.6 2.0 1 1 1 2 2 2 0 Calmodulin-binding DUF2232 PF09991.9 KFQ99892.1 - 0.17 11.0 1.0 0.2 10.8 1.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Ras PF00071.22 KFQ99893.1 - 3.8e-37 127.4 0.0 5.5e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ99893.1 - 7.3e-13 48.8 0.0 1.1e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ99893.1 - 4e-07 29.6 0.0 7.7e-07 28.7 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFQ99893.1 - 0.00032 20.3 0.0 0.0022 17.5 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFQ99893.1 - 0.009 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 KFQ99893.1 - 0.046 13.1 0.0 0.16 11.3 0.0 1.9 2 1 0 2 2 2 0 Bacterial TniB protein GAPT PF11770.8 KFQ99893.1 - 0.088 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) MMR_HSR1 PF01926.23 KFQ99893.1 - 0.09 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase PEMT PF04191.13 KFQ99894.1 - 1.2e-20 73.8 6.5 1.3e-20 73.7 4.3 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase Herpes_UL74 PF07982.12 KFQ99894.1 - 0.1 11.6 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Herpes UL74 glycoproteins HLH PF00010.26 KFQ99895.1 - 1.3e-18 66.7 1.2 2.8e-18 65.6 1.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PRKG1_interact PF15898.5 KFQ99895.1 - 0.032 15.1 0.9 0.032 15.1 0.9 1.9 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain VHS PF00790.19 KFQ99896.1 - 1.1e-44 151.7 0.1 3.2e-44 150.2 0.0 1.8 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 KFQ99896.1 - 1.3e-27 95.9 2.4 3.3e-27 94.6 2.4 1.8 1 0 0 1 1 1 1 GAT domain ENTH PF01417.20 KFQ99896.1 - 0.013 15.5 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 ENTH domain Pap_E4 PF02711.14 KFQ99896.1 - 1.6 9.7 8.1 0.41 11.6 0.7 2.9 3 0 0 3 3 3 0 E4 protein ATP12 PF07542.11 KFQ99897.1 - 3.9e-37 127.2 0.3 5.9e-37 126.6 0.3 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Vac_ImportDeg PF09783.9 KFQ99898.1 - 7.9e-55 185.1 5.0 8.9e-55 184.9 5.0 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein MMR_HSR1_Xtn PF16897.5 KFQ99899.1 - 5.8e-43 145.2 0.0 1.1e-42 144.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KFQ99899.1 - 4.9e-24 84.1 0.0 8.9e-24 83.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KFQ99899.1 - 9.4e-20 70.8 0.0 1.7e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFQ99899.1 - 6.2e-10 38.8 0.0 1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KFQ99899.1 - 0.023 14.8 0.3 1.5 8.8 0.0 2.3 1 1 1 2 2 2 0 Dynamin family 2OG-FeII_Oxy_2 PF13532.6 KFQ99900.1 - 3.7e-09 37.0 0.0 6e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ApoO PF09769.9 KFQ99900.1 - 0.069 13.1 0.2 0.12 12.3 0.2 1.3 1 0 0 1 1 1 0 Apolipoprotein O Gelsolin PF00626.22 KFQ99901.1 - 5.4e-64 212.1 2.5 2.8e-15 56.0 0.0 6.9 6 0 0 6 6 6 6 Gelsolin repeat LRR_8 PF13855.6 KFQ99901.1 - 7.2e-39 131.4 41.1 3.9e-09 36.1 9.4 6.6 5 1 1 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFQ99901.1 - 1.4e-21 76.2 58.4 6.1e-08 32.8 3.2 8.3 1 1 10 12 12 12 12 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFQ99901.1 - 2.5e-05 23.9 18.1 0.003 17.1 2.2 4.1 1 1 3 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 KFQ99901.1 - 0.00049 20.3 47.3 0.95 10.3 0.3 11.8 12 1 0 12 12 12 3 Leucine Rich Repeat SRP-alpha_N PF04086.13 KFQ99901.1 - 0.0094 15.9 1.0 0.0094 15.9 1.0 1.9 2 0 0 2 2 2 1 Signal recognition particle, alpha subunit, N-terminal Mab-21 PF03281.14 KFQ99902.1 - 1.5e-18 67.1 0.0 3.3e-18 66.0 0.0 1.5 1 1 0 1 1 1 1 Mab-21 protein Topoisom_bac PF01131.20 KFQ99903.1 - 1.8e-116 389.6 0.0 5.6e-116 387.9 0.0 1.7 2 0 0 2 2 2 1 DNA topoisomerase zf-GRF PF06839.12 KFQ99903.1 - 1.6e-37 127.3 20.7 1.5e-20 73.0 5.4 3.2 3 0 0 3 3 3 2 GRF zinc finger Toprim PF01751.22 KFQ99903.1 - 9.6e-18 64.3 0.0 9.3e-17 61.1 0.0 2.3 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 KFQ99903.1 - 1.1e-12 47.5 1.9 1.1e-12 47.5 1.9 3.5 4 0 0 4 4 4 1 Topoisomerase DNA binding C4 zinc finger zf-C2H2_10 PF16588.5 KFQ99903.1 - 0.0007 19.3 3.2 0.0019 17.9 3.2 1.7 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC_2 PF13696.6 KFQ99903.1 - 0.92 9.4 11.4 0.048 13.5 5.0 2.3 2 0 0 2 2 2 0 Zinc knuckle Folliculin PF11704.8 KFQ99904.1 - 2.1e-08 34.3 0.1 4.2e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport SHMT PF00464.19 KFQ99905.1 - 6.5e-195 647.3 0.0 8.2e-195 647.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 KFQ99905.1 - 0.00078 18.9 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family 7tm_1 PF00001.21 KFQ99906.1 - 3.1e-44 151.3 19.4 4.6e-44 150.7 19.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFQ99906.1 - 0.0011 18.7 11.3 0.0011 18.7 11.3 2.4 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx TraL PF07178.11 KFQ99906.1 - 0.092 13.2 3.9 0.17 12.4 0.1 2.7 2 0 0 2 2 2 0 TraL protein Pribosyl_synth PF14572.6 KFQ99907.1 - 4.2e-93 310.5 0.6 6.5e-93 309.9 0.6 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KFQ99907.1 - 1.4e-39 134.6 0.5 3.2e-39 133.5 0.5 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KFQ99907.1 - 4.7e-07 29.5 0.1 6.1e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl transferase domain UN_NPL4 PF11543.8 KFQ99907.1 - 0.04 14.4 0.0 0.077 13.5 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 RelB PF04221.12 KFQ99907.1 - 0.042 13.8 0.1 5.4 7.0 0.0 2.6 2 0 0 2 2 2 0 RelB antitoxin SWC7 PF17330.2 KFQ99907.1 - 0.13 12.3 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 SSF PF00474.17 KFQ99908.1 - 1.2e-142 475.6 20.4 1.5e-142 475.3 20.4 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family DUF2569 PF10754.9 KFQ99908.1 - 0.024 15.1 2.3 0.024 15.1 2.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2569) T2SSM PF04612.12 KFQ99908.1 - 0.1 12.6 0.8 0.25 11.4 0.8 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Toxin_2 PF00451.19 KFQ99908.1 - 0.23 11.8 2.4 0.42 11.0 2.4 1.4 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 SH2 PF00017.24 KFQ99909.1 - 1.2e-23 83.0 0.4 1.7e-23 82.5 0.4 1.3 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFQ99909.1 - 8.6e-22 76.5 0.1 3.3e-12 45.8 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KFQ99909.1 - 6.9e-19 67.4 0.1 1.4e-11 44.0 0.1 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KFQ99909.1 - 1.5e-16 59.8 0.0 2.5e-11 43.1 0.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain LydB PF16084.5 KFQ99909.1 - 0.1 12.4 0.0 1.1 9.1 0.0 2.1 1 1 1 2 2 2 0 LydA-holin antagonist ENTH PF01417.20 KFQ99910.1 - 9.2e-54 180.8 0.2 2.2e-53 179.6 0.2 1.7 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KFQ99910.1 - 3.6e-06 26.2 0.1 5.3e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 KFQ99910.1 - 7.7e-05 22.6 0.9 0.00014 21.7 0.3 1.7 2 0 0 2 2 2 1 VHS domain UIM PF02809.20 KFQ99910.1 - 1.6 8.9 14.3 0.21 11.6 5.1 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif B9-C2 PF07162.11 KFQ99911.1 - 8.7e-49 166.0 0.2 1e-48 165.8 0.2 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein C1q PF00386.21 KFQ99912.1 - 6.1e-36 123.4 1.7 7.7e-36 123.1 1.7 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFQ99912.1 - 3e-08 33.3 14.1 4.6e-08 32.7 14.1 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) GbpA_2 PF18416.1 KFQ99912.1 - 0.17 12.2 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 N-acetylglucosamine binding protein domain 2 7tm_1 PF00001.21 KFQ99913.1 - 2.7e-65 220.3 24.9 3.2e-65 220.1 24.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFQ99913.1 - 4.2e-15 55.8 21.1 4.9e-15 55.6 21.1 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFQ99913.1 - 8.6e-11 42.0 18.0 8.6e-11 42.0 18.0 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFQ99913.1 - 3.2e-08 33.3 18.1 4.7e-08 32.7 18.1 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv TctB PF07331.11 KFQ99913.1 - 0.006 16.9 8.8 0.006 16.9 8.8 2.7 1 1 1 2 2 2 1 Tripartite tricarboxylate transporter TctB family 7tm_4 PF13853.6 KFQ99913.1 - 2.5 7.8 19.8 33 4.1 19.8 2.5 1 1 0 1 1 1 0 Olfactory receptor HMG_box PF00505.19 KFQ99915.1 - 3.5e-05 24.1 1.0 6.7e-05 23.2 0.4 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box LMF1 PF06762.14 KFQ99916.1 - 2e-119 399.6 5.5 6.8e-69 233.1 0.1 2.0 1 1 1 2 2 2 2 Lipase maturation factor G-gamma PF00631.22 KFQ99918.1 - 9.3e-13 48.0 0.2 9.8e-13 47.9 0.2 1.0 1 0 0 1 1 1 1 GGL domain CSN4_RPN5_eIF3a PF18420.1 KFQ99918.1 - 0.027 14.7 0.3 0.042 14.0 0.3 1.5 1 0 0 1 1 1 0 CSN4/RPN5/eIF3a helix turn helix domain AAA PF00004.29 KFQ99920.1 - 6.5e-14 52.5 0.0 1.1e-13 51.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFQ99920.1 - 8.2e-10 38.8 0.0 1.7e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFQ99920.1 - 4.7e-08 32.9 0.0 7.9e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KFQ99920.1 - 7.1e-08 32.6 0.1 6e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 KFQ99920.1 - 1e-05 25.6 0.0 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFQ99920.1 - 2.1e-05 25.0 0.0 0.0056 17.1 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 KFQ99920.1 - 2.8e-05 24.4 0.0 0.0012 19.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFQ99920.1 - 0.0001 22.5 0.0 0.00023 21.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFQ99920.1 - 0.00047 20.7 0.0 0.00099 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFQ99920.1 - 0.00051 19.8 0.0 0.00082 19.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFQ99920.1 - 0.00055 19.7 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 KFQ99920.1 - 0.0012 18.4 0.0 0.0036 16.8 0.0 1.7 1 1 1 2 2 2 1 P-loop containing dynein motor region Viral_helicase1 PF01443.18 KFQ99920.1 - 0.0065 16.2 0.0 0.067 12.9 0.0 2.0 1 1 1 2 2 2 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 KFQ99920.1 - 0.0071 15.7 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 KFQ99920.1 - 0.0075 16.2 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 KFQ99920.1 - 0.0078 15.8 0.0 0.019 14.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KFQ99920.1 - 0.0093 15.9 0.0 0.17 11.8 0.0 2.2 1 1 1 2 2 2 1 NACHT domain NTPase_1 PF03266.15 KFQ99920.1 - 0.0095 15.9 0.2 0.21 11.5 0.0 2.3 1 1 1 2 2 2 1 NTPase TIP49 PF06068.13 KFQ99920.1 - 0.0099 15.1 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_3 PF07726.11 KFQ99920.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 KFQ99920.1 - 0.012 15.8 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.22 KFQ99920.1 - 0.012 14.8 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain TniB PF05621.11 KFQ99920.1 - 0.013 14.9 0.0 0.25 10.7 0.0 2.1 1 1 1 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 KFQ99920.1 - 0.016 15.0 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFQ99920.1 - 0.018 15.3 0.4 0.093 13.0 0.0 2.2 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 KFQ99920.1 - 0.023 15.2 0.0 0.055 14.0 0.0 1.6 1 1 1 2 2 1 0 ABC transporter AAA_17 PF13207.6 KFQ99920.1 - 0.025 15.0 0.0 0.057 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KFQ99920.1 - 0.026 14.8 0.2 0.26 11.6 0.1 2.2 1 1 1 2 2 2 0 AAA domain TsaE PF02367.17 KFQ99920.1 - 0.035 14.1 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KFQ99920.1 - 0.04 14.3 0.0 0.074 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NAD_binding_1 PF00175.21 KFQ99920.1 - 0.067 13.8 0.0 0.75 10.5 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain AAA_2 PF07724.14 KFQ99920.1 - 0.093 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) PseudoU_synth_2 PF00849.22 KFQ99921.1 - 6.8e-23 81.5 0.0 1e-22 81.0 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Mesothelin PF06060.12 KFQ99922.1 - 4e-11 41.8 0.1 4.4e-11 41.7 0.1 1.0 1 0 0 1 1 1 1 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) Mesothelin PF06060.12 KFQ99924.1 - 1e-135 453.4 0.2 1.3e-135 453.1 0.2 1.0 1 0 0 1 1 1 1 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) Fe_hyd_lg_C PF02906.14 KFQ99926.1 - 7.1e-75 251.8 0.0 1e-74 251.3 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 KFQ99926.1 - 2.5e-08 33.9 0.2 2.5e-08 33.9 0.2 1.7 2 0 0 2 2 2 1 Iron hydrogenase small subunit HAGH_C PF16123.5 KFQ99927.1 - 2.6e-24 85.5 0.3 4.6e-24 84.7 0.3 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KFQ99927.1 - 5.9e-09 36.2 1.6 3.5e-08 33.7 1.6 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFQ99927.1 - 0.00013 21.5 0.2 0.00024 20.7 0.2 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain HAGH_C PF16123.5 KFQ99928.1 - 3.8e-24 85.0 0.0 8e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KFQ99928.1 - 2.2e-11 44.1 0.6 7.7e-07 29.3 0.3 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFQ99928.1 - 0.00055 19.5 0.1 0.0012 18.4 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain REPA_OB_2 PF16900.5 KFQ99929.1 - 2.1e-07 30.7 0.0 8.3e-05 22.4 0.1 2.5 2 0 0 2 2 2 2 Replication protein A OB domain CDC24_OB3 PF17244.2 KFQ99929.1 - 3.6e-06 26.8 0.7 6.8e-05 22.7 0.9 2.2 2 0 0 2 2 2 1 Cell division control protein 24, OB domain 3 Sulfotransfer_1 PF00685.27 KFQ99930.1 - 5.4e-32 111.3 0.0 6.4e-32 111.1 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFQ99930.1 - 6.7e-12 46.3 0.0 9.1e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFQ99930.1 - 0.015 15.3 0.0 0.043 13.7 0.0 1.7 2 0 0 2 2 2 0 Sulfotransferase family SelR PF01641.18 KFQ99931.1 - 2.6e-16 59.8 0.4 2.9e-16 59.7 0.4 1.0 1 0 0 1 1 1 1 SelR domain Zn_ribbon_recom PF13408.6 KFQ99931.1 - 0.001 19.5 0.5 0.59 10.7 0.0 2.1 2 0 0 2 2 2 2 Recombinase zinc beta ribbon domain zinc_ribbon_2 PF13240.6 KFQ99931.1 - 0.014 15.1 3.4 0.56 10.0 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf_UBZ PF18439.1 KFQ99931.1 - 0.029 14.0 1.3 0.23 11.1 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF983 PF06170.12 KFQ99931.1 - 0.044 14.2 0.4 4.5 7.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) TF_Zn_Ribbon PF08271.12 KFQ99931.1 - 0.05 13.1 0.4 4.3 6.9 0.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding RIG-I_C-RD PF11648.8 KFQ99931.1 - 0.11 12.7 1.4 0.58 10.4 1.4 1.9 1 1 0 1 1 1 0 C-terminal domain of RIG-I TFIIS_C PF01096.18 KFQ99931.1 - 0.13 12.1 2.7 1.9 8.4 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.10 KFQ99931.1 - 0.16 12.1 1.9 1.7 8.8 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 KFQ99931.1 - 0.17 11.3 4.3 2.8 7.5 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.6 KFQ99931.1 - 0.18 11.6 4.5 3 7.7 0.5 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF1451 PF07295.11 KFQ99931.1 - 0.22 11.6 1.7 5.4 7.0 0.2 2.0 1 1 1 2 2 2 0 Zinc-ribbon containing domain DNA_RNApol_7kD PF03604.13 KFQ99931.1 - 0.34 10.6 3.3 1.8 8.3 0.1 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_4 PF13717.6 KFQ99931.1 - 0.39 10.7 3.9 3.4 7.7 0.5 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 KFQ99931.1 - 2 8.2 6.3 2.1 8.1 0.1 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain MMM1 PF10296.9 KFQ99933.1 - 1.4e-08 34.2 0.1 5e-07 29.1 0.0 2.2 2 0 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 Ribosomal_L3 PF00297.22 KFQ99934.1 - 1.5e-180 600.0 13.6 1.7e-180 599.8 13.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 RTX PF02382.15 KFQ99934.1 - 0.043 13.5 0.0 0.059 13.1 0.0 1.1 1 0 0 1 1 1 0 N-terminal domain in RTX protein NDUFB10 PF10249.9 KFQ99935.1 - 2.9e-52 176.5 6.2 3.4e-52 176.2 6.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 WW PF00397.26 KFQ99935.1 - 0.22 11.6 2.6 0.2 11.8 0.7 1.9 2 0 0 2 2 2 0 WW domain Ribosomal_S5 PF00333.20 KFQ99936.1 - 2.2e-31 107.7 0.4 4.1e-31 106.8 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KFQ99936.1 - 5.8e-27 93.0 0.0 1e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain WD40 PF00400.32 KFQ99937.1 - 1.8e-53 177.3 39.6 2.7e-07 31.2 0.4 11.5 11 0 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.11 KFQ99937.1 - 7.9e-41 139.3 2.2 1.4e-40 138.5 2.2 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 KFQ99937.1 - 2.3e-09 37.4 10.1 0.18 12.1 0.0 7.7 3 3 6 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFQ99937.1 - 4.4e-05 22.3 9.5 0.68 8.5 0.1 5.9 4 2 1 5 5 5 3 Nucleoporin Nup120/160 NUP214 PF16755.5 KFQ99937.1 - 8.4e-05 22.0 0.1 0.00042 19.7 0.0 2.1 2 0 0 2 2 2 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 Nucleoporin_N PF08801.11 KFQ99937.1 - 0.00065 18.6 3.3 2.9 6.5 0.1 4.9 3 2 3 6 6 6 2 Nup133 N terminal like WD40_like PF17005.5 KFQ99937.1 - 0.0031 16.9 0.5 3.5 6.8 0.0 4.3 3 3 1 5 5 5 1 WD40-like domain Ge1_WD40 PF16529.5 KFQ99937.1 - 0.0052 15.8 7.0 1 8.2 0.1 5.4 3 3 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein UTP15_C PF09384.10 KFQ99937.1 - 0.012 15.3 2.9 0.02 14.6 2.9 1.3 1 0 0 1 1 1 0 UTP15 C terminal LRRC37AB_C PF14914.6 KFQ99937.1 - 0.017 15.0 1.0 0.03 14.2 1.0 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain CP12 PF02672.15 KFQ99937.1 - 0.51 11.1 2.5 5.9 7.7 0.8 2.8 2 0 0 2 2 2 0 CP12 domain SH3_9 PF14604.6 KFQ99938.1 - 6.2e-15 54.8 0.0 9.1e-11 41.5 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KFQ99938.1 - 6.7e-15 54.4 0.9 1.3e-09 37.5 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KFQ99938.1 - 3.7e-13 48.9 0.0 2e-08 33.8 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 KFQ99938.1 - 3.5e-08 33.4 2.4 5.7e-08 32.7 1.4 1.9 2 0 0 2 2 2 1 PX domain SH3_3 PF08239.11 KFQ99938.1 - 5.5e-08 33.0 0.7 0.00066 19.9 0.1 2.4 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_4 PF06347.13 KFQ99938.1 - 5.6e-05 22.9 0.5 0.00046 19.9 0.1 2.2 2 0 0 2 2 2 1 Bacterial SH3 domain p47_phox_C PF08944.11 KFQ99938.1 - 0.00033 20.0 0.4 0.00033 20.0 0.4 1.9 2 0 0 2 2 2 1 NADPH oxidase subunit p47Phox, C terminal domain hSH3 PF14603.6 KFQ99938.1 - 0.006 17.0 0.0 2.5 8.6 0.0 2.6 1 1 0 2 2 2 2 Helically-extended SH3 domain Evr1_Alr PF04777.13 KFQ99939.1 - 8.7e-31 106.4 2.5 1e-30 106.1 2.5 1.0 1 0 0 1 1 1 1 Erv1 / Alr family DUF3970 PF13113.6 KFQ99939.1 - 0.0092 16.2 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3970) FAD_SOX PF18371.1 KFQ99939.1 - 0.073 13.4 0.0 0.29 11.5 0.0 1.7 1 1 1 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase MARVEL PF01284.23 KFQ99940.1 - 2.5e-20 73.0 12.7 2.9e-20 72.7 12.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF1129 PF06570.11 KFQ99940.1 - 0.039 13.4 0.4 0.058 12.9 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) HRG PF16954.5 KFQ99940.1 - 6.5 7.2 18.8 2.3 8.7 3.0 2.8 1 1 2 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene zf-C2H2_4 PF13894.6 KFQ99941.1 - 0.0035 18.0 30.8 0.026 15.4 0.2 6.7 5 1 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KFQ99941.1 - 0.0088 16.5 0.8 0.0088 16.5 0.8 6.0 6 0 0 6 6 6 3 Zinc finger, C2H2 type PDZ_6 PF17820.1 KFQ99942.1 - 2.1e-34 117.1 2.4 4.4e-16 58.5 0.1 2.3 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 KFQ99942.1 - 9.5e-32 109.2 0.3 7.3e-15 55.1 0.1 2.7 3 0 0 3 3 3 2 PDZ domain EBP50_C PF09007.11 KFQ99942.1 - 2.5e-30 106.1 5.4 2.1e-27 96.6 5.4 2.7 1 1 0 1 1 1 1 EBP50, C-terminal PDZ_2 PF13180.6 KFQ99942.1 - 1.5e-16 60.5 0.2 1.8e-07 31.4 0.0 2.9 3 0 0 3 3 3 2 PDZ domain GRASP55_65 PF04495.14 KFQ99942.1 - 2.1e-05 24.8 0.0 0.17 12.2 0.0 2.2 2 0 0 2 2 2 2 GRASP55/65 PDZ-like domain Tricorn_PDZ PF14685.6 KFQ99942.1 - 0.062 13.3 1.0 0.84 9.6 0.1 2.7 3 0 0 3 3 3 0 Tricorn protease PDZ domain Ribosomal_S17e PF00833.18 KFQ99942.1 - 1.7 8.6 4.7 3.5 7.6 0.1 2.6 3 0 0 3 3 3 0 Ribosomal S17 HhH-GPD PF00730.25 KFQ99943.1 - 6.5e-20 71.6 0.0 9.7e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KFQ99943.1 - 1.3e-08 34.3 0.0 2.3e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KFQ99943.1 - 0.091 13.4 0.0 0.58 10.8 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain PKD PF00801.20 KFQ99944.1 - 1.3e-164 534.3 90.7 1.8e-16 59.7 1.2 16.7 17 0 0 17 17 17 15 PKD domain REJ PF02010.15 KFQ99944.1 - 7.1e-109 364.6 0.7 3.8e-107 358.9 0.0 3.1 3 0 0 3 3 3 1 REJ domain PKD_channel PF08016.12 KFQ99944.1 - 2.9e-86 289.8 18.3 4.4e-86 289.2 18.3 1.3 1 0 0 1 1 1 1 Polycystin cation channel PLAT PF01477.23 KFQ99944.1 - 3.1e-22 79.3 0.1 1.2e-21 77.4 0.1 2.1 1 0 0 1 1 1 1 PLAT/LH2 domain LRR_8 PF13855.6 KFQ99944.1 - 2.2e-11 43.4 4.0 6.3e-11 41.9 4.0 1.9 1 0 0 1 1 1 1 Leucine rich repeat Lectin_C PF00059.21 KFQ99944.1 - 2.4e-11 44.3 2.7 3.3e-11 43.9 0.3 2.6 3 0 0 3 3 2 1 Lectin C-type domain Y_Y_Y PF07495.13 KFQ99944.1 - 7.4e-09 35.4 19.9 0.0016 18.4 0.0 7.3 7 0 0 7 7 7 3 Y_Y_Y domain LRR_4 PF12799.7 KFQ99944.1 - 0.0013 19.1 1.5 0.0013 19.1 1.5 2.6 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) WSC PF01822.19 KFQ99944.1 - 0.0014 18.8 9.0 0.0035 17.5 9.0 1.7 1 0 0 1 1 1 1 WSC domain GPS PF01825.21 KFQ99944.1 - 0.021 15.4 1.9 0.035 14.6 0.0 2.6 2 0 0 2 2 1 0 GPCR proteolysis site, GPS, motif LRRCT PF01463.24 KFQ99944.1 - 0.034 14.7 0.0 0.11 13.1 0.0 2.0 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain LRR_5 PF13306.6 KFQ99944.1 - 0.047 13.6 0.5 0.23 11.4 0.5 2.2 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) DUF1727 PF08353.10 KFQ99944.1 - 0.11 12.5 0.1 22 5.0 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1727) PKD_3 PF16820.5 KFQ99944.1 - 2.7 7.8 25.1 0.84 9.4 0.1 8.6 9 0 0 9 9 9 0 PKD-like domain LRR_1 PF00560.33 KFQ99944.1 - 3.5 8.5 4.2 1.6e+02 3.5 0.1 4.4 3 0 0 3 3 3 0 Leucine Rich Repeat Ras PF00071.22 KFQ99945.1 - 1.6e-59 200.1 0.2 1.8e-59 199.9 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFQ99945.1 - 2e-33 115.1 0.1 2.9e-33 114.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFQ99945.1 - 2.8e-14 53.0 0.1 3.1e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFQ99945.1 - 6e-06 25.8 0.1 8e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFQ99945.1 - 0.0002 21.4 0.0 0.00034 20.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFQ99945.1 - 0.00029 20.8 0.7 0.49 10.3 0.1 2.3 2 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KFQ99945.1 - 0.00055 19.5 0.2 0.0025 17.4 0.2 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KFQ99945.1 - 0.00061 19.4 0.2 0.0017 17.9 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFQ99945.1 - 0.0045 16.4 0.0 0.005 16.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Septin PF00735.18 KFQ99945.1 - 0.012 15.0 0.1 0.031 13.6 0.1 1.7 1 1 0 1 1 1 0 Septin AAA_16 PF13191.6 KFQ99945.1 - 0.012 16.0 0.1 0.025 14.9 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AsnC_trans_reg2 PF17805.1 KFQ99945.1 - 0.019 15.1 0.2 0.067 13.4 0.1 1.8 2 0 0 2 2 2 0 AsnC-like ligand binding domain AAA_22 PF13401.6 KFQ99945.1 - 0.047 13.9 0.1 0.16 12.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KFQ99945.1 - 0.071 13.5 0.1 0.92 9.9 0.0 2.5 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 KFQ99945.1 - 0.11 12.3 0.0 0.18 11.5 0.0 1.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 KFQ99945.1 - 0.11 12.4 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 NACHT domain WD40 PF00400.32 KFQ99946.1 - 1e-31 108.5 21.8 4.6e-08 33.6 1.2 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat WD40_like PF17005.5 KFQ99946.1 - 3.1e-08 33.3 1.3 5.8e-08 32.4 1.3 1.4 1 0 0 1 1 1 1 WD40-like domain zf-RING_UBOX PF13445.6 KFQ99946.1 - 1.5e-06 28.1 8.4 9.1e-06 25.6 8.4 2.5 1 0 0 1 1 1 1 RING-type zinc-finger Sina PF03145.16 KFQ99946.1 - 1.2e-05 25.4 10.6 0.0027 17.7 0.5 2.4 1 1 1 2 2 2 2 Seven in absentia protein family zf-TRAF PF02176.18 KFQ99946.1 - 2.7e-05 24.7 6.0 2.7e-05 24.7 6.0 2.7 3 1 0 3 3 2 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 KFQ99946.1 - 4.2e-05 23.3 14.3 4.2e-05 23.3 14.3 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFQ99946.1 - 4.5e-05 23.2 10.3 4.5e-05 23.2 10.3 3.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFQ99946.1 - 0.00023 21.3 7.3 0.00023 21.3 7.3 2.4 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING PKcGMP_CC PF16808.5 KFQ99946.1 - 0.0003 20.6 0.3 0.0026 17.5 0.0 2.4 2 0 0 2 2 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Nup160 PF11715.8 KFQ99946.1 - 0.00056 18.7 6.7 0.0032 16.2 0.5 3.7 3 1 1 4 4 4 1 Nucleoporin Nup120/160 zf-C3HC4_3 PF13920.6 KFQ99946.1 - 0.00057 19.7 11.4 0.00057 19.7 11.4 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFQ99946.1 - 0.0086 16.0 13.3 0.0086 16.0 13.3 3.2 3 0 0 3 3 2 1 zinc-RING finger domain Nucleoporin_N PF08801.11 KFQ99946.1 - 0.013 14.2 0.8 1.2 7.8 0.0 3.4 1 1 1 3 3 3 0 Nup133 N terminal like KxDL PF10241.9 KFQ99946.1 - 0.025 14.9 0.5 0.053 13.8 0.5 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF16 PF01519.16 KFQ99946.1 - 0.035 14.6 0.6 0.072 13.6 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 PQQ_3 PF13570.6 KFQ99946.1 - 0.076 13.5 2.4 21 5.8 0.1 4.8 5 1 0 5 5 4 0 PQQ-like domain DUF641 PF04859.12 KFQ99946.1 - 0.087 13.2 0.2 0.15 12.4 0.2 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) HSBP1 PF06825.12 KFQ99946.1 - 2 8.4 4.7 16 5.5 4.7 2.1 1 1 0 1 1 1 0 Heat shock factor binding protein 1 zf-Nse PF11789.8 KFQ99946.1 - 2.7 7.9 11.8 2.2 8.1 7.3 2.8 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 KFQ99946.1 - 8.2 6.6 18.4 1.7 8.8 10.4 2.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_2 PF13639.6 KFQ99946.1 - 9 6.7 20.4 0.7 10.3 13.3 2.9 2 0 0 2 2 2 0 Ring finger domain Glyco_hydro_20 PF00728.22 KFQ99947.1 - 2.4e-11 43.6 0.0 4.3e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain BRICHOS PF04089.14 KFQ99949.1 - 7.7e-19 67.7 0.2 1.3e-18 67.0 0.2 1.4 1 0 0 1 1 1 1 BRICHOS domain LIF_OSM PF01291.17 KFQ99949.1 - 0.028 14.5 0.5 0.041 14.0 0.5 1.2 1 0 0 1 1 1 0 LIF / OSM family ISN1 PF06437.11 KFQ99949.1 - 0.042 12.8 0.0 0.046 12.6 0.0 1.1 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase Peptidase_S66C PF17676.1 KFQ99949.1 - 0.14 12.7 0.0 0.22 12.1 0.0 1.3 1 0 0 1 1 1 0 LD-carboxypeptidase C-terminal domain Hydrolase_like PF13242.6 KFQ99950.1 - 1.1e-19 70.3 0.0 1.7e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 KFQ99950.1 - 0.00031 20.9 0.0 0.00039 20.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFQ99950.1 - 0.00049 20.5 0.0 0.0006 20.2 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KFQ99950.1 - 0.00064 19.4 0.1 0.00092 18.9 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase zf-C2H2 PF00096.26 KFQ99951.1 - 6.2e-40 133.5 69.0 5.9e-05 23.3 3.2 10.4 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFQ99951.1 - 4e-34 115.5 75.0 4.4e-08 33.2 1.7 10.5 11 0 0 11 11 10 8 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFQ99951.1 - 2.3e-33 112.0 66.3 0.00079 20.1 2.0 10.4 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFQ99951.1 - 1.7e-21 76.0 31.1 0.00024 21.3 0.3 10.1 10 0 0 10 10 10 7 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFQ99951.1 - 2.2e-07 30.5 38.9 0.00098 18.8 0.1 8.7 10 0 0 10 10 10 4 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFQ99951.1 - 2.1e-05 24.3 36.9 0.09 12.7 0.3 8.3 8 0 0 8 8 8 3 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 KFQ99951.1 - 3.6e-05 23.8 47.2 0.048 13.8 3.5 8.4 6 3 3 9 9 9 3 Zinc ribbon domain zf-C2H2_6 PF13912.6 KFQ99951.1 - 5.1e-05 23.2 66.9 0.075 13.1 1.1 10.0 10 0 0 10 10 10 4 C2H2-type zinc finger DUF3268 PF11672.8 KFQ99951.1 - 0.00015 22.1 20.9 0.012 16.0 0.7 4.4 3 2 1 4 4 4 3 zinc-finger-containing domain zf-C2H2_8 PF15909.5 KFQ99951.1 - 0.00021 21.5 33.8 0.076 13.3 1.1 6.0 3 2 3 6 6 6 3 C2H2-type zinc ribbon zinc_ribbon_9 PF14369.6 KFQ99951.1 - 0.00091 19.4 20.6 0.097 13.0 0.0 7.3 7 0 0 7 7 7 1 zinc-ribbon zf-met PF12874.7 KFQ99951.1 - 0.0012 19.2 0.6 0.0012 19.2 0.6 8.3 9 0 0 9 9 9 2 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 KFQ99951.1 - 0.0062 17.3 30.3 2.2 9.1 0.2 5.6 4 2 2 6 6 6 3 zinc-ribbon family zf_UBZ PF18439.1 KFQ99951.1 - 0.0067 16.0 37.8 1.4 8.6 0.2 9.4 10 0 0 10 10 10 3 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 KFQ99951.1 - 0.013 15.8 42.8 0.33 11.3 0.2 8.7 3 2 6 9 9 9 0 C2H2 type zinc-finger (2 copies) DZR PF12773.7 KFQ99951.1 - 0.02 14.9 34.5 6.7 6.8 5.2 6.0 3 2 0 3 3 3 0 Double zinc ribbon XPA_N PF01286.18 KFQ99951.1 - 0.076 13.1 0.3 0.076 13.1 0.3 7.8 10 0 0 10 10 10 0 XPA protein N-terminal Zn-C2H2_12 PF18112.1 KFQ99951.1 - 0.11 12.9 9.0 2.3 8.8 0.1 4.9 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain zf-MYST PF17772.1 KFQ99951.1 - 0.12 12.0 16.5 3.2 7.4 0.1 5.2 5 0 0 5 5 5 0 MYST family zinc finger domain zf-Di19 PF05605.12 KFQ99951.1 - 1.5 9.2 41.6 0.33 11.3 0.5 6.8 3 2 3 7 7 7 0 Drought induced 19 protein (Di19), zinc-binding ADK_lid PF05191.14 KFQ99951.1 - 6.2 6.9 33.8 3.7 7.6 1.3 6.7 4 2 3 7 7 6 0 Adenylate kinase, active site lid Zn_Tnp_IS1595 PF12760.7 KFQ99951.1 - 6.3 6.9 51.0 1.3 9.1 7.3 7.0 5 3 0 5 5 4 0 Transposase zinc-ribbon domain DHHC PF01529.20 KFQ99952.1 - 5.3e-32 110.7 15.8 5.3e-32 110.7 15.8 2.9 2 1 0 2 2 2 1 DHHC palmitoyltransferase OppC_N PF12911.7 KFQ99952.1 - 0.78 9.8 0.0 0.78 9.8 0.0 3.8 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C IGFBP PF00219.18 KFQ99952.1 - 9.3 7.0 9.6 3.3 8.4 5.6 2.0 2 0 0 2 2 2 0 Insulin-like growth factor binding protein FH2 PF02181.23 KFQ99953.1 - 4.2e-91 305.9 9.3 5.6e-91 305.4 9.3 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain PDZ PF00595.24 KFQ99953.1 - 2.9e-13 50.0 0.0 5.4e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFQ99953.1 - 5.1e-08 32.6 0.0 1.4e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFQ99953.1 - 0.0008 19.7 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain RMI1_N PF08585.12 KFQ99953.1 - 1.4 8.7 3.6 0.82 9.4 0.0 2.1 2 0 0 2 2 2 0 RecQ mediated genome instability protein SSF PF00474.17 KFQ99954.1 - 1.6e-145 485.1 20.3 2.2e-145 484.6 20.3 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family IBV_3C PF03620.13 KFQ99954.1 - 0.029 14.9 1.8 0.077 13.5 0.3 2.5 2 0 0 2 2 2 0 IBV 3C protein BLUF PF04940.12 KFQ99955.1 - 0.0026 17.8 0.0 0.043 14.0 0.0 2.3 2 1 0 2 2 2 1 Sensors of blue-light using FAD LCM PF04072.14 KFQ99956.1 - 2.4e-37 128.7 0.0 4e-37 128.0 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase MIP PF00230.20 KFQ99957.1 - 0.00016 21.5 0.0 0.00018 21.3 0.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Pkinase PF00069.25 KFQ99958.1 - 1.1e-61 208.5 0.0 1.5e-61 208.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ99958.1 - 4.9e-38 130.9 0.0 7.2e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 KFQ99958.1 - 4.5e-27 94.3 0.1 7.3e-27 93.7 0.1 1.3 1 0 0 1 1 1 1 C2 domain C1_1 PF00130.22 KFQ99958.1 - 2.7e-19 68.8 17.0 1.4e-17 63.3 5.8 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KFQ99958.1 - 0.00015 22.4 1.5 0.00035 21.2 1.5 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFQ99958.1 - 0.0069 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFQ99958.1 - 0.024 13.6 0.0 0.036 13.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain CEP76-C2 PF15627.6 KFQ99958.1 - 0.045 13.3 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 CEP76 C2 domain APH PF01636.23 KFQ99958.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Aerolysin PF01117.20 KFQ99958.1 - 0.096 11.9 0.1 2.3 7.3 0.0 2.1 1 1 1 2 2 2 0 Aerolysin toxin Pkinase_C PF00433.24 KFQ99959.1 - 5.8e-11 42.9 1.5 7.3e-11 42.6 1.5 1.2 1 0 0 1 1 1 1 Protein kinase C terminal domain PMP22_Claudin PF00822.20 KFQ99960.1 - 1.1e-53 181.5 1.1 1.5e-53 181.1 1.1 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFQ99960.1 - 2.3e-19 69.9 0.3 4.1e-19 69.1 0.3 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction zf-CCHC_2 PF13696.6 KFQ99961.1 - 2.5e-09 36.8 6.8 2.5e-09 36.8 6.8 1.8 2 0 0 2 2 1 1 Zinc knuckle U-box PF04564.15 KFQ99961.1 - 3.1e-07 30.5 0.0 1.2e-06 28.6 0.0 2.0 1 0 0 1 1 1 1 U-box domain zf-C3HC4_2 PF13923.6 KFQ99961.1 - 1.4e-05 24.8 11.3 1.4e-05 24.8 11.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC PF00098.23 KFQ99961.1 - 2.3e-05 24.2 2.7 4.6e-05 23.3 2.7 1.5 1 0 0 1 1 1 1 Zinc knuckle DWNN PF08783.11 KFQ99961.1 - 4e-05 23.8 3.8 5.2e-05 23.4 0.2 2.8 2 0 0 2 2 2 1 DWNN domain zf-C3HC4_3 PF13920.6 KFQ99961.1 - 4.3e-05 23.3 9.7 4.3e-05 23.3 9.7 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFQ99961.1 - 0.0013 18.6 11.0 0.0033 17.4 11.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFQ99961.1 - 0.0028 17.9 11.7 0.0054 17.0 11.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KFQ99961.1 - 0.014 15.5 11.9 0.039 14.1 11.9 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KFQ99961.1 - 0.017 15.0 12.2 0.034 14.0 12.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFQ99961.1 - 0.18 11.9 10.2 0.43 10.6 10.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.6 KFQ99961.1 - 0.36 10.7 4.5 0.75 9.7 4.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 KFQ99961.1 - 0.41 10.5 10.2 0.87 9.5 10.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DZR PF12773.7 KFQ99961.1 - 2.3 8.3 9.2 2.5 8.2 4.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon TNRC6-PABC_bdg PF16608.5 KFQ99962.1 - 1.5e-121 405.7 33.6 1.5e-121 405.7 33.6 7.3 6 2 0 6 6 6 1 TNRC6-PABC binding domain Ago_hook PF10427.9 KFQ99962.1 - 2.2e-14 54.3 20.5 2.2e-14 54.3 20.5 11.3 3 2 4 7 7 7 1 Argonaute hook RRM_1 PF00076.22 KFQ99962.1 - 0.0013 18.5 0.0 0.0032 17.2 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PP-binding PF00550.25 KFQ99963.1 - 1.2e-12 48.0 0.1 1.5e-12 47.7 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KFQ99963.1 - 0.001 19.3 0.2 0.0012 19.0 0.2 1.1 1 0 0 1 1 1 1 Acyl-carrier PALB2_WD40 PF16756.5 KFQ99964.1 - 1.7e-174 579.8 0.7 2.2e-174 579.4 0.7 1.1 1 0 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain Hexapep PF00132.24 KFQ99965.1 - 6.7e-16 57.3 22.7 4.7e-06 26.1 2.9 4.3 3 1 2 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFQ99965.1 - 0.00013 21.6 9.5 0.0042 16.8 0.5 3.9 3 2 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KFQ99965.1 - 0.0077 14.4 0.3 0.0092 14.2 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 KFQ99965.1 - 0.038 12.9 1.7 0.083 11.8 1.3 1.7 1 1 1 2 2 2 0 L-fucokinase Pkinase PF00069.25 KFQ99966.1 - 9.3e-48 162.9 0.0 1.4e-47 162.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain POLO_box PF00659.18 KFQ99966.1 - 3.2e-43 145.8 1.0 6.4e-21 74.3 0.5 2.4 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_Tyr PF07714.17 KFQ99966.1 - 2e-26 92.9 0.0 3e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFQ99966.1 - 3.9e-06 25.9 0.0 5.6e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFQ99966.1 - 7.2e-06 25.5 0.0 9.6e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFQ99966.1 - 0.089 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KFQ99967.1 - 2.9e-40 138.3 0.0 4.2e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 KFQ99967.1 - 4.7e-40 136.7 0.0 8.6e-40 135.8 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 KFQ99967.1 - 1.1e-22 80.6 0.0 1.7e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 KFQ99967.1 - 1.6e-08 34.1 0.2 0.0038 17.1 0.0 3.4 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_2 PF13360.6 KFQ99967.1 - 6.6e-08 32.4 0.0 0.00081 19.0 0.0 2.6 2 1 0 2 2 2 2 PQQ-like domain Pkinase_fungal PF17667.1 KFQ99967.1 - 0.0014 17.5 0.0 0.0029 16.5 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFQ99967.1 - 0.0033 17.4 0.5 0.17 11.8 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KFQ99967.1 - 0.0054 16.1 0.0 0.0092 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ_3 PF13570.6 KFQ99967.1 - 0.53 10.9 8.8 34 5.1 0.0 5.8 7 0 0 7 7 7 0 PQQ-like domain ubiquitin PF00240.23 KFQ99968.1 - 4.2e-13 48.8 0.0 8.5e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KFQ99968.1 - 0.00067 20.1 0.0 0.0043 17.5 0.0 2.3 1 1 1 2 2 2 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KFQ99968.1 - 0.0037 17.6 0.2 0.0077 16.6 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain tRNA-synt_1c PF00749.21 KFQ99969.1 - 1.6e-82 276.9 0.0 2.4e-82 276.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain TetR_C_7 PF14246.6 KFQ99969.1 - 0.093 12.8 0.0 0.47 10.5 0.0 2.2 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain Pox_A6 PF04924.12 KFQ99969.1 - 0.12 11.2 0.2 0.19 10.6 0.2 1.2 1 0 0 1 1 1 0 Poxvirus A6 protein VHS PF00790.19 KFQ99970.1 - 2.8e-44 150.4 3.3 1.2e-43 148.3 0.0 2.7 3 0 0 3 3 3 1 VHS domain GGA_N-GAT PF18308.1 KFQ99970.1 - 7.4e-19 67.1 5.0 7.4e-19 67.1 5.0 2.3 2 0 0 2 2 2 1 GGA N-GAT domain GAT PF03127.14 KFQ99970.1 - 5.1e-17 61.9 8.1 1e-16 61.0 3.7 2.7 2 0 0 2 2 2 1 GAT domain CHGN PF05679.16 KFQ99970.1 - 0.017 14.0 0.1 0.024 13.5 0.1 1.4 1 0 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase DUF2959 PF11172.8 KFQ99970.1 - 0.033 14.3 6.7 0.039 14.1 5.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) SRP_SPB PF02978.19 KFQ99970.1 - 0.053 14.2 0.5 0.12 13.0 0.5 1.6 1 0 0 1 1 1 0 Signal peptide binding domain Cytochrom_C_2 PF01322.20 KFQ99970.1 - 0.11 13.4 0.2 0.32 11.9 0.0 1.9 2 1 0 2 2 2 0 Cytochrome C' PCRF PF03462.18 KFQ99970.1 - 0.12 12.3 5.6 0.24 11.2 5.6 1.6 1 0 0 1 1 1 0 PCRF domain Flagellin_N PF00669.20 KFQ99970.1 - 0.17 12.0 2.5 0.3 11.2 2.5 1.6 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region DUF3837 PF12939.7 KFQ99970.1 - 0.3 11.5 3.4 0.56 10.6 1.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3837) FUSC PF04632.12 KFQ99970.1 - 1.7 7.1 3.5 2.1 6.8 3.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family COG7 PF10191.9 KFQ99971.1 - 8.2e-303 1006.5 16.9 9.9e-303 1006.2 16.9 1.0 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) ICE2 PF08426.10 KFQ99971.1 - 0.013 14.6 0.4 0.025 13.7 0.4 1.4 1 0 0 1 1 1 0 ICE2 FlgN PF05130.12 KFQ99971.1 - 0.82 10.2 12.0 8.9 6.8 0.5 3.0 2 1 0 2 2 2 0 FlgN protein ASC PF00858.24 KFQ99972.1 - 4.4e-113 378.6 6.0 8.3e-113 377.7 6.0 1.4 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel Toxin_TOLIP PF00087.21 KFQ99972.1 - 0.0017 18.6 1.8 0.0054 17.0 1.8 1.8 1 0 0 1 1 1 1 Snake toxin and toxin-like protein ASC PF00858.24 KFQ99973.1 - 4e-104 349.0 14.3 4.7e-104 348.8 14.3 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel UCH PF00443.29 KFQ99974.1 - 1.9e-42 145.6 0.0 5.8e-42 144.0 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFQ99974.1 - 6.1e-13 49.0 0.1 9.2e-08 32.0 0.1 3.1 1 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Zn_Tnp_IS1595 PF12760.7 KFQ99974.1 - 0.23 11.5 3.2 9.7 6.3 0.0 3.1 3 0 0 3 3 3 0 Transposase zinc-ribbon domain zinc_ribbon_10 PF10058.9 KFQ99974.1 - 0.64 9.8 5.2 13 5.6 0.0 3.0 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Sulfotransfer_1 PF00685.27 KFQ99975.1 - 3.2e-35 121.9 0.0 3.6e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFQ99975.1 - 1.4e-11 45.2 0.0 2.1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFQ99975.1 - 0.011 15.7 0.1 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 Sulfotransferase family Sulfotransfer_1 PF00685.27 KFQ99976.1 - 9.2e-33 113.8 0.0 1.1e-32 113.6 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFQ99976.1 - 7.6e-11 42.8 0.0 1.1e-10 42.2 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFQ99976.1 - 0.0049 16.8 0.0 0.079 12.8 0.0 2.1 2 0 0 2 2 2 1 Sulfotransferase family Cupin_8 PF13621.6 KFQ99977.1 - 1.2e-45 156.2 0.2 1.5e-45 155.9 0.2 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KFQ99977.1 - 2.4e-06 27.3 0.0 7.7e-06 25.6 0.0 1.7 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 KFQ99977.1 - 0.026 15.0 0.1 0.097 13.1 0.1 1.9 1 1 0 1 1 1 0 JmjC domain, hydroxylase SMC_Nse1 PF07574.13 KFQ99978.1 - 2.5e-28 99.3 0.9 1.3e-26 93.7 0.9 2.0 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KFQ99978.1 - 1.1e-09 38.4 9.2 1.1e-09 38.4 9.2 2.5 3 0 0 3 3 3 1 RING-like domain Zn_ribbon_17 PF17120.5 KFQ99978.1 - 0.017 14.8 6.3 0.038 13.6 6.3 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 KFQ99978.1 - 0.087 12.7 12.1 0.044 13.7 9.7 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4822 PF16103.5 KFQ99978.1 - 0.14 12.5 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4822) zf-ribbon_3 PF13248.6 KFQ99978.1 - 0.24 10.9 6.5 0.39 10.2 0.8 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_2 PF13923.6 KFQ99978.1 - 0.53 10.2 9.7 1.3 9.0 9.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IL4Ra_N PF09238.10 KFQ99979.1 - 2.3e-27 95.2 5.7 2.3e-27 95.2 5.7 2.1 2 0 0 2 2 2 1 Interleukin-4 receptor alpha chain, N-terminal fn3 PF00041.21 KFQ99979.1 - 9.6e-05 22.7 0.4 0.00046 20.5 0.6 2.1 2 0 0 2 2 2 1 Fibronectin type III domain EpoR_lig-bind PF09067.10 KFQ99979.1 - 0.0016 18.6 4.7 0.0016 18.6 4.7 2.0 2 0 0 2 2 2 1 Erythropoietin receptor, ligand binding IL6Ra-bind PF09240.10 KFQ99979.1 - 0.033 14.6 4.3 0.066 13.6 4.3 1.5 1 0 0 1 1 1 0 Interleukin-6 receptor alpha chain, binding IL2RB_N1 PF18707.1 KFQ99979.1 - 2.3 8.8 8.1 3.3 8.3 4.3 2.3 2 0 0 2 2 2 0 Interleukin-2 receptor subunit beta N-terminal domain 1 fn3 PF00041.21 KFQ99981.1 - 0.01 16.1 1.0 0.033 14.5 1.0 1.9 1 1 0 1 1 1 0 Fibronectin type III domain PhnJ PF06007.11 KFQ99981.1 - 0.061 12.3 0.1 0.096 11.7 0.1 1.2 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ Pur_ac_phosph_N PF16656.5 KFQ99981.1 - 0.57 10.8 3.5 0.34 11.5 0.8 2.0 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain IL4Ra_N PF09238.10 KFQ99981.1 - 2.2 8.7 6.9 10 6.6 0.3 3.5 3 0 0 3 3 3 0 Interleukin-4 receptor alpha chain, N-terminal Pkinase PF00069.25 KFQ99983.1 - 1.3e-66 224.7 0.0 1.5e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFQ99983.1 - 2e-34 119.1 0.0 2.7e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.6 KFQ99983.1 - 6e-29 100.2 0.0 1.1e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 KFQ99983.1 - 1e-06 28.3 0.0 1.8e-06 27.5 0.0 1.4 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFQ99983.1 - 9e-06 24.7 0.4 1.6e-05 23.9 0.4 1.5 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFQ99983.1 - 2.7e-05 23.3 0.1 4.3e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KFQ99983.1 - 0.0019 17.8 0.0 1.9 8.1 0.0 2.3 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KFQ99983.1 - 0.0066 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFQ99983.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family BTB_2 PF02214.22 KFQ99984.1 - 3.7e-11 43.2 0.0 6.1e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KFQ99984.1 - 0.025 14.8 0.0 0.041 14.1 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain zf-RING_9 PF13901.6 KFQ99984.1 - 0.062 13.3 0.0 0.079 12.9 0.0 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon SAM_LFY PF01698.16 KFQ99984.1 - 0.094 12.7 0.1 0.17 11.8 0.0 1.4 1 1 0 1 1 1 0 Floricaula / Leafy protein SAM domain UQ_con PF00179.26 KFQ99985.1 - 2.1e-49 166.8 0.0 2.4e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFQ99985.1 - 4.3e-05 23.2 0.0 4.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Ribo_biogen_C PF04034.13 KFQ99986.1 - 1.3e-54 183.3 0.0 1.7e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KFQ99986.1 - 2e-12 46.7 1.1 3.9e-12 45.8 1.1 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI PRKCSH_1 PF13015.6 KFQ99987.1 - 4.4e-10 39.5 0.5 5.5e-09 35.9 0.0 2.3 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KFQ99987.1 - 1.8e-07 32.0 3.0 1.8e-07 32.0 3.0 2.4 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein LRRFIP PF09738.9 KFQ99987.1 - 0.0025 17.3 4.4 0.0034 16.9 4.4 1.2 1 0 0 1 1 1 1 LRRFIP family Lipoprotein_X PF03305.13 KFQ99987.1 - 0.0061 16.3 0.9 0.0096 15.7 0.9 1.4 1 0 0 1 1 1 1 Mycoplasma MG185/MG260 protein Syntaxin-18_N PF10496.9 KFQ99987.1 - 0.021 15.1 2.7 0.037 14.3 2.7 1.3 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus VP_N-CPKC PF11475.8 KFQ99987.1 - 0.082 12.8 0.6 0.88 9.5 0.1 2.6 2 0 0 2 2 2 0 Virion protein N terminal domain YscO PF07321.12 KFQ99987.1 - 0.2 11.6 5.0 0.29 11.1 5.0 1.2 1 0 0 1 1 1 0 Type III secretion protein YscO Ribosomal_L30_N PF08079.12 KFQ99987.1 - 0.22 11.8 4.1 0.38 11.0 4.1 1.4 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain zf_CCCH_5 PF18384.1 KFQ99988.1 - 3.6e-20 71.8 14.6 3.6e-20 71.8 14.6 2.8 2 1 0 2 2 2 1 Unkempt Zinc finger domain 1 (Znf1) zf-CCCH PF00642.24 KFQ99988.1 - 1.2e-06 28.3 8.3 7.7e-06 25.7 2.2 6.6 6 0 0 6 6 6 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFQ99988.1 - 0.0013 18.7 26.0 0.048 13.7 0.0 5.9 5 0 0 5 5 5 2 Zinc finger domain Filament PF00038.21 KFQ99988.1 - 0.0024 17.5 6.5 0.0045 16.6 6.5 1.4 1 0 0 1 1 1 1 Intermediate filament protein Golgin_A5 PF09787.9 KFQ99988.1 - 0.052 13.0 4.5 0.089 12.2 4.5 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 FapA PF03961.13 KFQ99988.1 - 0.092 11.3 0.1 0.14 10.8 0.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF932 PF06067.11 KFQ99988.1 - 0.17 11.7 2.8 0.27 11.0 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF932) Torus PF16131.5 KFQ99988.1 - 0.19 12.4 0.1 0.19 12.4 0.1 5.3 4 2 2 6 6 6 0 Torus domain MAD PF05557.13 KFQ99988.1 - 0.25 9.7 9.3 0.34 9.2 9.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Rep_4 PF05797.11 KFQ99988.1 - 0.49 9.5 2.1 0.75 8.9 2.1 1.2 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) PCRF PF03462.18 KFQ99988.1 - 0.61 9.9 4.2 1.1 9.2 4.2 1.3 1 0 0 1 1 1 0 PCRF domain DUF3560 PF12083.8 KFQ99988.1 - 0.86 9.7 5.6 1.8 8.7 5.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) Prominin PF05478.11 KFQ99988.1 - 0.89 7.4 3.8 1.3 6.9 3.8 1.1 1 0 0 1 1 1 0 Prominin Alanine_zipper PF11839.8 KFQ99988.1 - 1.3 9.4 10.2 2.1 8.8 10.2 1.3 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein Fz PF01392.22 KFQ99997.1 - 1.5e-26 93.2 1.8 1.5e-26 93.2 1.8 1.9 2 0 0 2 2 2 1 Fz domain NTR PF01759.21 KFQ99997.1 - 1.1e-20 73.4 3.1 1.3e-20 73.1 0.7 1.9 1 1 1 2 2 2 1 UNC-6/NTR/C345C module Nckap1 PF09735.9 KFQ99998.1 - 0 1680.2 28.0 0 1680.0 28.0 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein DSPc PF00782.20 KFQ99999.1 - 3.6e-31 107.7 0.0 4.1e-31 107.6 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFQ99999.1 - 0.00068 19.3 0.0 0.00071 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KFQ99999.1 - 0.15 12.4 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain Nup35_RRM PF05172.13 KFR00001.1 - 5.1e-27 93.8 0.0 8.3e-27 93.1 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 KFR00001.1 - 7.1e-11 41.9 0.0 1.1e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-C2H2_jaz PF12171.8 KFR00002.1 - 7.9e-06 26.0 9.2 7.9e-06 26.0 9.2 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding DFRP_C PF16543.5 KFR00003.1 - 1.6e-22 79.8 2.1 1.6e-22 79.8 2.1 3.9 4 0 0 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH_4 PF18044.1 KFR00003.1 - 7.5e-09 35.2 6.1 9.7e-07 28.5 1.2 3.3 3 0 0 3 3 3 2 CCCH-type zinc finger Torus PF16131.5 KFR00003.1 - 2.8e-07 31.2 10.7 1.8e-05 25.4 2.8 3.2 1 1 1 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KFR00003.1 - 1.2e-06 28.4 6.1 1.2e-06 28.4 6.1 3.3 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH PF00642.24 KFR00003.1 - 2.7e-06 27.1 2.6 2.7e-06 27.1 0.9 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KFR00003.1 - 0.0089 16.5 12.4 0.056 13.9 3.9 3.0 2 1 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KFR00003.1 - 0.018 15.2 8.0 0.17 12.1 3.0 3.1 1 1 1 2 2 2 0 Zinc-finger containing family Integrin_alpha2 PF08441.12 KFR00004.1 - 4.1e-123 411.7 0.0 5e-123 411.4 0.0 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 KFR00004.1 - 8.9e-30 102.5 19.6 1.6e-09 37.7 0.2 4.6 4 0 0 4 4 4 4 FG-GAP repeat VCBS PF13517.6 KFR00004.1 - 1.8e-14 54.0 11.4 1.4e-05 25.6 0.7 4.4 3 1 1 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.20 KFR00004.1 - 7.9e-05 22.3 0.7 0.00017 21.3 0.7 1.6 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region LYRIC PF15686.5 KFR00004.1 - 0.00016 21.4 0.0 0.00025 20.8 0.0 1.2 1 0 0 1 1 1 1 Lysine-rich CEACAM1 co-isolated protein family UPF0560 PF10577.9 KFR00005.1 - 4.1e-146 488.7 10.9 1.1e-98 331.8 2.4 2.1 1 1 1 2 2 2 2 Uncharacterised protein family UPF0560 Prominin PF05478.11 KFR00005.1 - 0.00057 18.0 0.0 0.00094 17.3 0.0 1.2 1 0 0 1 1 1 1 Prominin Orthoreo_P10 PF07204.11 KFR00005.1 - 0.077 13.0 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 7tm_2 PF00002.24 KFR00006.1 - 1.5e-80 270.1 19.3 1.9e-80 269.7 19.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFR00006.1 - 1.6e-18 66.7 8.0 3.1e-18 65.8 8.0 1.5 1 0 0 1 1 1 1 Hormone receptor domain DUF4034 PF13226.6 KFR00006.1 - 0.082 12.3 0.4 0.15 11.4 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4034) DUF2070 PF09843.9 KFR00006.1 - 2 6.6 9.0 2.9 6.1 9.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PID PF00640.23 KFR00007.1 - 1.4e-30 106.2 0.6 2e-30 105.6 0.6 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFR00007.1 - 3.7e-12 46.5 0.3 6.7e-12 45.7 0.3 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.6 KFR00007.1 - 1.1e-05 25.3 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Ax_dynein_light PF10211.9 KFR00007.1 - 0.0014 18.7 0.3 0.0022 18.0 0.3 1.3 1 0 0 1 1 1 1 Axonemal dynein light chain TSC22 PF01166.18 KFR00007.1 - 0.0039 17.5 2.1 0.012 15.9 2.1 1.8 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF2004 PF09406.10 KFR00007.1 - 0.0039 17.5 0.2 0.013 15.8 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2004) DivIC PF04977.15 KFR00007.1 - 0.004 16.9 4.7 0.0073 16.0 4.7 1.3 1 0 0 1 1 1 1 Septum formation initiator bZIP_2 PF07716.15 KFR00007.1 - 0.0076 16.3 4.7 0.0076 16.3 4.7 1.6 2 0 0 2 2 1 1 Basic region leucine zipper ZapB PF06005.12 KFR00007.1 - 0.012 16.1 2.5 0.023 15.1 2.5 1.4 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_1 PF00170.21 KFR00007.1 - 0.012 15.7 2.0 0.022 14.8 2.0 1.4 1 0 0 1 1 1 0 bZIP transcription factor KASH_CCD PF14662.6 KFR00007.1 - 0.015 15.1 0.7 0.028 14.3 0.7 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Pox_A_type_inc PF04508.12 KFR00007.1 - 0.016 15.0 2.9 0.099 12.5 0.2 2.6 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat gpW PF02831.15 KFR00007.1 - 0.02 14.8 0.1 0.039 13.9 0.1 1.5 1 1 0 1 1 1 0 gpW HAP1_N PF04849.13 KFR00007.1 - 0.021 14.0 0.3 0.03 13.5 0.3 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF4337 PF14235.6 KFR00007.1 - 0.022 14.9 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Cnn_1N PF07989.11 KFR00007.1 - 0.026 14.7 0.6 0.053 13.7 0.6 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 TMF_DNA_bd PF12329.8 KFR00007.1 - 0.04 13.9 1.8 0.04 13.9 1.8 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Herpes_UL6 PF01763.16 KFR00007.1 - 0.044 12.3 0.2 0.075 11.5 0.2 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like Spc24 PF08286.11 KFR00007.1 - 0.048 13.9 0.5 0.1 12.8 0.5 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 BST2 PF16716.5 KFR00007.1 - 0.054 14.1 1.9 0.13 12.9 1.9 1.6 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 APG6_N PF17675.1 KFR00007.1 - 0.067 13.7 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region GIT_CC PF16559.5 KFR00007.1 - 0.08 12.8 0.5 0.08 12.8 0.5 1.8 2 0 0 2 2 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor CCD48 PF15799.5 KFR00007.1 - 0.13 10.6 0.6 0.26 9.5 0.6 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 48 SlyX PF04102.12 KFR00007.1 - 0.14 12.8 1.8 0.37 11.4 1.8 1.7 1 0 0 1 1 1 0 SlyX Pro_isomerase PF00160.21 KFR00011.1 - 1e-41 142.9 0.0 1.1e-41 142.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 7tm_1 PF00001.21 KFR00014.1 - 1.5e-42 145.7 12.7 1.8e-42 145.5 12.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFR00014.1 - 8.5e-10 38.7 12.4 8.5e-10 38.7 12.4 1.5 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFR00014.1 - 4.7e-08 32.7 14.5 1e-07 31.6 14.5 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFR00014.1 - 1.7e-05 24.7 8.9 0.00071 19.4 1.9 2.1 2 0 0 2 2 2 2 Olfactory receptor HCV_core PF01542.18 KFR00014.1 - 0.04 14.3 0.1 0.1 13.0 0.1 1.6 1 0 0 1 1 1 0 Hepatitis C virus core protein DUF1673 PF07895.11 KFR00014.1 - 0.12 12.0 7.7 0.65 9.7 1.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1673) zf-LITAF-like PF10601.9 KFR00014.1 - 0.18 12.1 4.9 4.6 7.6 0.2 3.5 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain Peptidase_M56 PF05569.11 KFR00014.1 - 0.24 10.5 1.4 0.8 8.8 0.1 2.2 2 0 0 2 2 2 0 BlaR1 peptidase M56 Aph-1 PF06105.12 KFR00029.1 - 1.2e-83 280.1 15.1 1.3e-83 279.9 15.1 1.0 1 0 0 1 1 1 1 Aph-1 protein YqfD PF06898.11 KFR00029.1 - 0.0063 15.4 1.0 0.0094 14.8 1.0 1.1 1 0 0 1 1 1 1 Putative stage IV sporulation protein YqfD Carb_anhydrase PF00194.21 KFR00030.1 - 1.5e-53 181.9 0.1 1.3e-25 90.4 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic-type carbonic anhydrase Syndecan PF01034.20 KFR00030.1 - 0.17 11.8 1.0 0.33 10.9 1.0 1.4 1 0 0 1 1 1 0 Syndecan domain ER-remodelling PF14755.6 KFR00032.1 - 0.14 12.4 3.1 0.17 12.2 3.1 1.2 1 0 0 1 1 1 0 Intracellular membrane remodeller Cadherin PF00028.17 KFR00033.1 - 5.8e-80 263.8 5.2 1.1e-19 70.6 0.1 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFR00033.1 - 2e-57 193.6 0.3 3.8e-57 192.7 0.3 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_3 PF16184.5 KFR00033.1 - 4.5e-06 26.6 6.8 0.073 13.1 0.1 5.3 6 0 0 6 6 6 2 Cadherin-like Cadherin_2 PF08266.12 KFR00033.1 - 0.00052 19.8 0.0 1.7 8.5 0.0 4.3 4 1 0 4 4 4 1 Cadherin-like Invasin_D3 PF09134.10 KFR00033.1 - 0.0046 17.2 1.8 8 6.9 0.1 4.2 4 0 0 4 4 4 1 Invasin, domain 3 ASFV_J13L PF05568.11 KFR00033.1 - 0.067 12.9 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein Big_9 PF17963.1 KFR00033.1 - 0.1 13.4 10.8 23 5.8 1.4 4.7 4 0 0 4 4 4 0 Bacterial Ig domain Cadherin_pro PF08758.11 KFR00033.1 - 0.16 12.1 0.0 6.6 7.0 0.0 3.1 3 0 0 3 3 3 0 Cadherin prodomain like Stevor PF17410.2 KFR00033.1 - 0.17 11.4 0.1 0.3 10.6 0.1 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Cadherin_4 PF17803.1 KFR00033.1 - 0.25 12.0 14.7 1.7 9.3 2.6 4.5 4 1 0 4 4 4 0 Bacterial cadherin-like domain T4SS_TraI PF16932.5 KFR00034.1 - 0.058 12.6 1.0 0.22 10.7 0.2 1.9 2 0 0 2 2 2 0 Type IV secretory system, conjugal DNA-protein transfer RVT_1 PF00078.27 KFR00035.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFR00036.1 - 0.0029 17.2 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UBA_3 PF09288.10 KFR00036.1 - 0.16 11.8 0.0 0.4 10.5 0.0 1.7 1 1 1 2 2 2 0 Fungal ubiquitin-associated domain wnt PF00110.19 KFR00037.1 - 1.9e-121 405.4 24.2 2.1e-121 405.2 24.2 1.0 1 0 0 1 1 1 1 wnt family EndoU_bacteria PF14436.6 KFR00037.1 - 0.15 12.4 0.0 0.51 10.7 0.0 1.8 1 1 0 1 1 1 0 Bacterial EndoU nuclease VWA_N PF08399.11 KFR00038.1 - 4.7e-31 107.8 0.2 9.9e-31 106.8 0.2 1.6 1 0 0 1 1 1 1 VWA N-terminal VGCC_alpha2 PF08473.11 KFR00038.1 - 2.7e-28 98.9 8.6 6.4e-28 97.7 7.9 1.9 2 1 0 2 2 2 1 Neuronal voltage-dependent calcium channel alpha 2acd dCache_1 PF02743.18 KFR00038.1 - 2.4e-15 57.0 1.4 2.5e-11 43.8 0.1 3.6 2 2 1 3 3 3 2 Cache domain VWA_3 PF13768.6 KFR00038.1 - 4.5e-14 52.7 0.0 9.4e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KFR00038.1 - 5.4e-12 46.3 0.1 1e-11 45.4 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFR00038.1 - 1.3e-09 38.6 0.0 2.7e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain dCache_2 PF08269.11 KFR00038.1 - 0.001 18.3 0.1 0.0038 16.5 0.1 1.9 2 0 0 2 2 2 1 Cache domain Cache_3-Cache_2 PF17201.4 KFR00038.1 - 0.0073 15.6 0.0 0.024 13.9 0.1 1.8 2 0 0 2 2 2 1 Cache 3/Cache 2 fusion domain VWA_CoxE PF05762.14 KFR00038.1 - 0.027 13.8 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein LRR_8 PF13855.6 KFR00039.1 - 3.9e-24 84.2 17.5 3.5e-16 58.7 5.3 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFR00039.1 - 1.2e-08 35.0 21.9 0.00078 19.8 2.5 3.6 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFR00039.1 - 1.1e-07 31.6 6.0 0.0016 18.0 2.0 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_5 PF13306.6 KFR00039.1 - 5.3e-07 29.6 0.5 9.6e-07 28.8 0.5 1.4 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFR00039.1 - 1.4e-05 25.0 12.9 0.046 14.3 0.2 5.0 5 0 0 5 5 5 2 Leucine Rich Repeat LRRNT PF01462.18 KFR00039.1 - 0.042 13.5 0.5 0.042 13.5 0.5 2.2 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 KFR00039.1 - 0.054 13.6 15.1 0.16 12.1 0.1 4.7 5 0 0 5 5 5 0 Leucine Rich repeat tRNA-synt_2b PF00587.25 KFR00054.1 - 4.1e-36 124.6 0.0 7.8e-36 123.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KFR00054.1 - 7.5e-20 70.9 0.0 1.7e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 KFR00054.1 - 6.3e-18 64.6 0.1 2.8e-17 62.5 0.0 2.1 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.14 KFR00054.1 - 1.5e-12 47.4 0.1 3.6e-12 46.2 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TSP_1 PF00090.19 KFR00055.1 - 5.1e-38 129.1 121.5 8.2e-10 38.8 7.9 10.7 10 0 0 10 10 10 8 Thrombospondin type 1 domain ADAM_spacer1 PF05986.14 KFR00055.1 - 1.2e-33 115.5 0.1 3.5e-33 114.0 0.0 1.8 2 0 0 2 2 2 1 ADAM-TS Spacer 1 Pep_M12B_propep PF01562.19 KFR00055.1 - 2.6e-33 115.2 1.0 6e-33 114.0 1.0 1.7 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 KFR00055.1 - 8.2e-27 94.4 0.0 1.8e-26 93.3 0.0 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 KFR00055.1 - 8e-21 74.3 7.6 8e-21 74.3 7.6 6.5 6 2 0 6 6 6 2 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 KFR00055.1 - 6.8e-15 55.7 0.3 1.8e-14 54.3 0.0 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFR00055.1 - 2.2e-08 34.7 0.2 6.8e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFR00055.1 - 5.5e-05 23.1 0.2 0.00021 21.3 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFR00055.1 - 0.00016 21.4 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like PLAC PF08686.11 KFR00055.1 - 0.81 10.5 7.1 7.3 7.4 7.1 2.9 1 0 0 1 1 1 0 PLAC (protease and lacunin) domain HEV_ORF1 PF02444.16 KFR00056.1 - 0.074 13.6 5.8 0.085 13.4 5.8 1.2 1 0 0 1 1 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) 7tm_1 PF00001.21 KFR00057.1 - 2.9e-48 164.5 15.4 3.6e-48 164.2 15.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MFS_2 PF13347.6 KFR00058.1 - 3e-08 32.6 3.0 3e-08 32.6 3.0 3.0 2 1 1 3 3 3 1 MFS/sugar transport protein DUF2298 PF10060.9 KFR00058.1 - 0.0055 15.5 1.3 0.0055 15.5 1.3 2.2 2 0 0 2 2 2 1 Uncharacterized membrane protein (DUF2298) CoA_transf_3 PF02515.17 KFR00059.1 - 1.3e-53 182.5 0.0 1.5e-53 182.3 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III C1q PF00386.21 KFR00060.1 - 4.3e-33 114.2 3.4 5.2e-33 114.0 3.4 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFR00060.1 - 5.9e-13 48.4 57.1 3.1e-10 39.7 32.5 2.0 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Baculo_LEF-3 PF05847.11 KFR00060.1 - 0.042 13.1 0.1 0.052 12.7 0.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus late expression factor 3 (LEF-3) VWA PF00092.28 KFR00061.1 - 1.9e-37 129.2 0.2 3.1e-37 128.5 0.2 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Integrin_alpha2 PF08441.12 KFR00061.1 - 1.9e-29 102.9 0.0 2.4e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 KFR00061.1 - 2.3e-13 50.0 17.9 1.7e-06 28.0 0.5 4.7 5 0 0 5 5 5 3 FG-GAP repeat VWA_2 PF13519.6 KFR00061.1 - 7.9e-10 39.3 0.1 2e-09 38.0 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VCBS PF13517.6 KFR00061.1 - 3.1e-07 30.9 0.4 0.00011 22.7 0.1 3.7 3 1 1 4 4 4 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF11 PF01345.18 KFR00061.1 - 0.01 16.1 0.1 12 6.3 0.7 2.6 1 1 0 2 2 2 0 Domain of unknown function DUF11 VWA_CoxE PF05762.14 KFR00061.1 - 0.02 14.3 0.0 0.052 12.9 0.0 1.6 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein FG-GAP_2 PF14312.6 KFR00061.1 - 0.076 13.3 4.7 0.15 12.4 0.1 3.9 4 0 0 4 4 4 0 FG-GAP repeat zf-H2C2_2 PF13465.6 KFR00062.1 - 2.2e-82 268.1 81.3 5.5e-09 36.0 0.7 12.4 13 0 0 13 13 12 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFR00062.1 - 6.7e-71 231.0 87.0 1.7e-07 31.3 1.0 12.6 12 1 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR00062.1 - 3.2e-41 136.4 78.5 0.00026 21.5 0.3 12.1 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFR00062.1 - 2.3e-17 62.8 36.7 0.064 13.6 0.0 11.9 11 1 1 12 12 12 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFR00062.1 - 3.8e-17 61.8 93.8 0.00041 20.3 0.3 12.9 12 1 0 12 12 12 8 C2H2-type zinc finger zf_UBZ PF18439.1 KFR00062.1 - 4.1e-17 61.5 31.3 0.65 9.6 0.0 12.1 12 0 0 12 12 12 7 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFR00062.1 - 1.5e-12 47.4 55.8 0.0014 18.7 2.2 9.4 5 3 5 10 10 10 8 Zinc ribbon domain XPA_N PF01286.18 KFR00062.1 - 1.2e-10 41.2 38.5 1.7 8.7 0.1 11.9 12 0 0 12 12 12 3 XPA protein N-terminal zf-LYAR PF08790.11 KFR00062.1 - 4.3e-08 32.9 32.3 0.76 9.7 0.3 11.3 12 0 0 12 12 12 3 LYAR-type C2HC zinc finger C1_4 PF07975.12 KFR00062.1 - 1.6e-07 31.5 35.4 0.37 11.1 0.1 8.0 3 2 6 9 9 9 5 TFIIH C1-like domain zinc_ribbon_15 PF17032.5 KFR00062.1 - 3.4e-07 30.9 33.8 0.47 11.3 0.9 6.4 2 2 3 7 7 7 4 zinc-ribbon family DZR PF12773.7 KFR00062.1 - 3.7e-07 30.1 51.3 1.8 8.7 7.1 6.9 1 1 1 2 2 1 1 Double zinc ribbon DNA_RNApol_7kD PF03604.13 KFR00062.1 - 5.1e-06 26.1 53.0 1.1 9.0 0.0 11.3 11 0 0 11 11 11 2 DNA directed RNA polymerase, 7 kDa subunit Zn_ribbon_SprT PF17283.2 KFR00062.1 - 9.2e-06 25.5 68.2 0.0025 17.7 1.2 10.3 5 5 4 9 9 9 3 SprT-like zinc ribbon domain zf-Di19 PF05605.12 KFR00062.1 - 0.00014 22.0 38.0 0.016 15.4 0.6 7.7 1 1 10 11 11 11 4 Drought induced 19 protein (Di19), zinc-binding HypA PF01155.19 KFR00062.1 - 0.00016 21.7 34.3 1.2 9.2 2.5 6.5 1 1 5 6 6 6 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FYDLN_acid PF09538.10 KFR00062.1 - 0.00093 19.8 23.6 26 5.5 0.1 10.2 1 1 10 11 11 11 0 Protein of unknown function (FYDLN_acid) DUF3268 PF11672.8 KFR00062.1 - 0.0035 17.7 31.8 0.75 10.1 0.6 6.3 2 1 2 7 7 7 2 zinc-finger-containing domain Zn_ribbon_recom PF13408.6 KFR00062.1 - 0.005 17.3 70.3 1.8 9.1 4.3 10.5 2 2 9 11 11 11 1 Recombinase zinc beta ribbon domain CpXC PF14353.6 KFR00062.1 - 0.15 12.1 39.1 16 5.5 0.6 10.5 6 2 2 10 10 10 0 CpXC protein Zn-C2H2_12 PF18112.1 KFR00062.1 - 0.38 11.3 15.0 10 6.7 0.1 7.1 8 0 0 8 8 6 0 Autophagy receptor zinc finger-C2H2 domain GAGA PF09237.11 KFR00062.1 - 0.9 9.4 29.0 1.8 8.4 0.0 6.9 4 3 3 8 8 8 0 GAGA factor zf-C2HE PF16278.5 KFR00062.1 - 1.6 9.3 52.7 0.88 10.1 0.2 9.9 2 2 8 10 10 10 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 KFR00062.1 - 1.8 9.1 48.7 1.3 9.6 2.4 10.4 11 0 0 11 11 11 0 Zinc-finger of C2H2 type ADK_lid PF05191.14 KFR00062.1 - 2.3 8.3 30.7 15 5.7 0.5 8.2 4 4 3 7 7 7 0 Adenylate kinase, active site lid zf-AN1 PF01428.16 KFR00062.1 - 3.3 7.9 64.3 1.3 9.3 3.7 11.9 8 3 4 12 12 12 0 AN1-like Zinc finger LIM PF00412.22 KFR00062.1 - 3.6 7.9 39.5 1.2 9.5 0.8 8.3 3 3 6 9 9 9 0 LIM domain zinc_ribbon_4 PF13717.6 KFR00062.1 - 4.3 7.3 44.0 12 5.9 0.8 10.7 8 3 1 9 9 9 0 zinc-ribbon domain Lipase_GDSL_2 PF13472.6 KFR00071.1 - 8e-17 62.2 0.0 9.7e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFR00071.1 - 0.0004 20.4 0.0 0.00058 19.9 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KFR00071.1 - 0.093 12.9 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Pkinase PF00069.25 KFR00072.1 - 4e-67 226.4 0.0 7.7e-67 225.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR00072.1 - 1.6e-35 122.6 1.5 3.3e-35 121.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR00072.1 - 7.8e-06 25.4 0.0 1.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFR00072.1 - 0.0036 16.7 0.7 0.0094 15.3 0.7 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFR00072.1 - 0.064 12.2 0.1 0.064 12.2 0.1 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Apolipoprotein PF01442.18 KFR00073.1 - 6e-48 163.2 20.4 6.7e-48 163.1 20.4 1.0 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 KFR00073.1 - 2e-08 34.6 12.9 0.00047 20.6 0.9 3.7 1 1 2 3 3 3 2 YtxH-like protein Baculo_PEP_C PF04513.12 KFR00073.1 - 4.3e-06 26.8 0.6 0.27 11.3 0.1 3.1 1 1 2 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.13 KFR00073.1 - 4.8e-06 27.1 13.1 0.021 15.4 3.5 4.1 1 1 4 5 5 5 3 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.11 KFR00073.1 - 9.8e-06 25.7 8.2 0.0042 17.2 4.2 2.7 1 1 1 2 2 2 2 Apolipophorin-III precursor (apoLp-III) DUF4455 PF14643.6 KFR00073.1 - 1.4e-05 24.0 9.8 1.8e-05 23.6 9.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) DUF948 PF06103.11 KFR00073.1 - 0.00012 22.2 2.4 0.42 10.9 0.0 3.9 1 1 2 3 3 3 1 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 KFR00073.1 - 0.00058 19.9 4.5 0.28 11.2 0.6 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 KFR00073.1 - 0.00071 19.2 7.0 0.001 18.7 7.0 1.4 1 0 0 1 1 1 1 Exonuclease VII, large subunit PIN_8 PF18476.1 KFR00073.1 - 0.0017 18.3 7.8 0.0094 15.8 1.7 2.1 1 1 1 2 2 2 1 PIN like domain Prominin PF05478.11 KFR00073.1 - 0.002 16.2 4.7 0.0066 14.5 4.9 1.6 1 1 0 1 1 1 1 Prominin RapH_N PF18801.1 KFR00073.1 - 0.0022 18.0 11.9 0.1 12.7 0.5 3.5 3 1 0 3 3 3 2 response regulator aspartate phosphatase H, N terminal BORCS6 PF10157.9 KFR00073.1 - 0.0022 18.2 0.2 0.27 11.4 0.0 2.8 1 1 1 2 2 2 1 BLOC-1-related complex sub-unit 6 DUF773 PF05600.12 KFR00073.1 - 0.0045 15.8 8.6 0.0054 15.5 8.6 1.1 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 Atypical_Card PF18461.1 KFR00073.1 - 0.0059 16.8 4.3 0.39 11.0 1.0 2.2 1 1 1 2 2 2 1 Atypical caspase recruitment domain T7SS_ESX_EspC PF10824.8 KFR00073.1 - 0.0078 16.7 0.1 3.7 8.1 0.0 2.9 2 2 1 3 3 2 0 Excreted virulence factor EspC, type VII ESX diderm DUF1978 PF09321.10 KFR00073.1 - 0.0094 15.3 3.9 0.0094 15.3 3.9 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF1978) VirE PF05272.11 KFR00073.1 - 0.012 15.3 4.3 0.023 14.4 0.4 2.3 1 1 1 2 2 2 0 Virulence-associated protein E DUF445 PF04286.12 KFR00073.1 - 0.013 15.4 6.9 0.027 14.3 7.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) ApoA-II PF04711.13 KFR00073.1 - 0.013 15.7 9.9 0.4 10.9 1.2 3.9 1 1 2 3 3 3 0 Apolipoprotein A-II (ApoA-II) Fib_alpha PF08702.10 KFR00073.1 - 0.015 15.5 5.1 0.19 11.9 2.1 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family 4HB_MCP_1 PF12729.7 KFR00073.1 - 0.016 14.7 10.0 0.016 14.7 5.1 2.2 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction APP_E2 PF12925.7 KFR00073.1 - 0.018 14.8 9.2 0.37 10.5 0.1 2.6 1 1 1 2 2 2 0 E2 domain of amyloid precursor protein KxDL PF10241.9 KFR00073.1 - 0.018 15.3 10.3 1.7 9.0 0.2 4.0 1 1 4 5 5 5 0 Uncharacterized conserved protein QIL1 PF15884.5 KFR00073.1 - 0.019 15.6 8.4 20 5.9 0.1 4.8 1 1 4 5 5 5 0 MICOS complex subunit MIC13, QIL1 pRN1_helical PF13010.6 KFR00073.1 - 0.02 14.9 2.3 0.8 9.7 0.1 2.3 2 0 0 2 2 2 0 Primase helical domain DUF2937 PF11157.8 KFR00073.1 - 0.02 14.6 4.7 0.11 12.2 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2937) BAG6 PF12057.8 KFR00073.1 - 0.021 14.5 8.8 9 6.0 0.0 4.5 1 1 4 5 5 5 0 BCL2-associated athanogene 6 DUF4456 PF14644.6 KFR00073.1 - 0.023 14.4 11.5 0.048 13.3 7.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4456) DUF4015 PF13200.6 KFR00073.1 - 0.025 13.6 1.2 0.043 12.9 0.4 1.8 1 1 0 1 1 1 0 Putative glycosyl hydrolase domain OmpH PF03938.14 KFR00073.1 - 0.028 14.8 18.8 0.09 13.1 7.6 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) ApoO PF09769.9 KFR00073.1 - 0.035 14.1 5.2 0.8 9.7 1.2 3.3 1 1 1 2 2 2 0 Apolipoprotein O Snapin_Pallidin PF14712.6 KFR00073.1 - 0.036 14.5 12.5 0.35 11.3 2.3 2.7 1 1 1 2 2 2 0 Snapin/Pallidin DUF2884 PF11101.8 KFR00073.1 - 0.047 13.2 5.0 0.11 11.9 1.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) DLP_helical PF18709.1 KFR00073.1 - 0.058 12.6 8.0 0.052 12.8 4.4 2.5 1 1 1 2 2 2 0 Dynamin-like helical domain BshC PF10079.9 KFR00073.1 - 0.058 12.1 13.8 0.1 11.3 8.7 2.0 1 1 1 2 2 2 0 Bacillithiol biosynthesis BshC Prefoldin PF02996.17 KFR00073.1 - 0.059 13.3 12.9 4.9 7.1 0.1 4.3 1 1 4 5 5 4 0 Prefoldin subunit NPV_P10 PF05531.12 KFR00073.1 - 0.061 13.8 3.2 2.7 8.5 0.9 3.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1451 PF07295.11 KFR00073.1 - 0.063 13.3 10.3 0.048 13.7 4.2 2.4 1 1 1 2 2 2 0 Zinc-ribbon containing domain Mer2 PF09074.10 KFR00073.1 - 0.066 13.0 3.0 0.12 12.1 2.9 1.5 1 1 0 1 1 1 0 Mer2 DUF1054 PF06335.12 KFR00073.1 - 0.066 13.1 3.8 3.5 7.5 0.1 3.3 1 1 0 3 3 3 0 Protein of unknown function (DUF1054) DUF1640 PF07798.11 KFR00073.1 - 0.067 13.2 10.1 18 5.4 10.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF668 PF05003.12 KFR00073.1 - 0.076 13.5 5.9 0.36 11.3 0.3 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF668) ACP_PD PF04336.12 KFR00073.1 - 0.077 13.4 4.5 1.4 9.4 0.6 2.7 1 1 1 2 2 2 0 Acyl carrier protein phosphodiesterase DUF5063 PF16702.5 KFR00073.1 - 0.087 13.2 3.6 5.6 7.3 1.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5063) Imm49 PF15575.6 KFR00073.1 - 0.1 12.4 5.6 0.11 12.2 2.6 2.0 1 1 1 2 2 2 0 Immunity protein 49 DpnI_C PF17726.1 KFR00073.1 - 0.1 12.7 0.9 0.97 9.6 0.1 2.8 2 1 1 3 3 2 0 Dam-replacing HTH domain Atg14 PF10186.9 KFR00073.1 - 0.11 11.6 8.4 0.14 11.2 8.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CHASE6_C PF17150.4 KFR00073.1 - 0.11 13.2 5.7 1.8 9.3 0.8 2.9 1 1 1 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain ACP53EA PF06313.11 KFR00073.1 - 0.11 12.7 0.1 23 5.3 0.0 3.3 3 1 1 4 4 3 0 Drosophila ACP53EA protein His_Phos_1 PF00300.22 KFR00073.1 - 0.12 12.1 5.0 0.21 11.3 1.0 2.2 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) DUF2935 PF11155.8 KFR00073.1 - 0.14 12.5 1.5 1.1 9.6 1.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Erp_C PF06780.11 KFR00073.1 - 0.14 12.1 6.1 0.33 11.0 0.2 2.5 1 1 0 2 2 2 0 Erp protein C-terminus DUF72 PF01904.18 KFR00073.1 - 0.15 12.2 5.2 0.51 10.4 2.5 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF72 KMP11 PF03037.16 KFR00073.1 - 0.17 12.7 5.9 2.2 9.1 0.9 3.1 1 1 2 3 3 3 0 Kinetoplastid membrane protein 11 Peptidase_S46 PF10459.9 KFR00073.1 - 0.18 10.4 8.5 0.21 10.2 8.5 1.0 1 0 0 1 1 1 0 Peptidase S46 TipAS PF07739.13 KFR00073.1 - 0.2 12.2 11.3 12 6.5 10.2 3.1 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain Cas_DxTHG PF09455.10 KFR00073.1 - 0.2 11.2 10.4 1 8.9 9.2 1.9 1 1 1 2 2 2 0 CRISPR-associated (Cas) DxTHG family 7TMR-HDED PF07697.11 KFR00073.1 - 0.21 11.7 11.1 0.42 10.7 11.1 1.5 1 1 0 1 1 1 0 7TM-HD extracellular DUF1690 PF07956.11 KFR00073.1 - 0.27 11.7 15.1 5 7.5 0.2 2.9 1 1 2 3 3 3 0 Protein of Unknown function (DUF1690) TetR_C_37 PF18665.1 KFR00073.1 - 0.27 11.8 4.8 5.2 7.7 0.2 3.3 2 2 2 4 4 3 0 Tetracyclin repressor-like, C-terminal domain PGK PF00162.19 KFR00073.1 - 0.3 10.0 2.7 0.34 9.8 0.9 1.8 1 1 1 2 2 2 0 Phosphoglycerate kinase TPD52 PF04201.15 KFR00073.1 - 0.36 10.4 10.9 4.2 7.0 4.3 2.3 1 1 1 2 2 2 0 Tumour protein D52 family NDUF_B6 PF09782.9 KFR00073.1 - 0.38 10.9 4.5 1 9.5 4.0 2.1 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit FAM184 PF15665.5 KFR00073.1 - 0.42 10.4 16.7 4.7 6.9 6.6 2.4 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Lipase_GDSL PF00657.22 KFR00073.1 - 0.46 10.4 1.3 26 4.7 1.3 2.6 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase Flu_NS2 PF00601.19 KFR00073.1 - 0.48 10.8 9.0 2.2 8.6 0.2 3.8 1 1 3 4 4 4 0 Influenza non-structural protein (NS2) Histidinol_dh PF00815.20 KFR00073.1 - 0.52 9.3 4.0 0.67 8.9 1.7 1.9 1 1 1 2 2 2 0 Histidinol dehydrogenase DUF148 PF02520.17 KFR00073.1 - 0.54 10.4 8.5 5.6 7.1 1.5 3.0 1 1 0 2 2 2 0 Domain of unknown function DUF148 TetR_C_6 PF13977.6 KFR00073.1 - 0.56 10.5 6.1 8.7 6.6 0.1 3.7 1 1 2 4 4 4 0 BetI-type transcriptional repressor, C-terminal FUSC PF04632.12 KFR00073.1 - 0.56 8.7 9.3 7.9 4.9 9.3 2.1 1 1 0 1 1 1 0 Fusaric acid resistance protein family Cnn_1N PF07989.11 KFR00073.1 - 0.61 10.3 14.4 7.1 6.9 3.5 3.6 1 1 3 4 4 4 0 Centrosomin N-terminal motif 1 IZUMO PF15005.6 KFR00073.1 - 0.7 10.4 9.1 16 6.0 4.5 2.8 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated FAM76 PF16046.5 KFR00073.1 - 0.81 9.0 11.6 0.6 9.4 1.5 2.0 2 0 0 2 2 2 0 FAM76 protein TPR_MLP1_2 PF07926.12 KFR00073.1 - 0.89 9.6 19.5 1.6 8.8 12.9 3.1 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein TMPIT PF07851.13 KFR00073.1 - 0.92 8.7 8.4 0.73 9.0 3.0 2.1 1 1 1 2 2 2 0 TMPIT-like protein COG2 PF06148.11 KFR00073.1 - 1.1 9.3 12.4 12 6.0 2.8 3.8 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Muted PF14942.6 KFR00073.1 - 1.2 9.4 12.6 2.6 8.4 9.7 2.3 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein CorA PF01544.18 KFR00073.1 - 1.2 8.3 4.8 3.5 6.8 4.7 1.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein YlqD PF11068.8 KFR00073.1 - 1.3 9.4 15.5 1 9.7 2.8 2.5 1 1 1 2 2 2 0 YlqD protein DUF4407 PF14362.6 KFR00073.1 - 1.3 8.3 6.0 2 7.7 6.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DctP PF03480.13 KFR00073.1 - 1.3 8.3 12.8 1.6 8.0 0.7 2.8 1 1 2 3 3 3 0 Bacterial extracellular solute-binding protein, family 7 CENP-H PF05837.12 KFR00073.1 - 1.4 9.4 17.9 0.59 10.6 9.0 3.0 1 1 2 3 3 3 0 Centromere protein H (CENP-H) KapB PF08810.10 KFR00073.1 - 1.4 9.1 8.0 4.5 7.5 2.0 3.3 1 1 3 4 4 4 0 Kinase associated protein B Uso1_p115_C PF04871.13 KFR00073.1 - 1.4 9.2 18.3 16 5.8 1.8 2.8 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region WXG100 PF06013.12 KFR00073.1 - 1.6 9.1 5.5 21 5.4 0.5 4.0 1 1 4 5 5 4 0 Proteins of 100 residues with WXG FapA PF03961.13 KFR00073.1 - 1.8 7.1 12.7 1.5 7.3 3.0 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A DEDD_Tnp_IS110 PF01548.17 KFR00073.1 - 2 8.3 5.0 1.9 8.3 0.1 2.8 3 1 0 3 3 3 0 Transposase kleA_kleC PF17383.2 KFR00073.1 - 2.1 8.7 11.8 8.6 6.8 6.1 3.6 2 1 0 2 2 2 0 Uncharacterized KorC regulated protein A FliH PF02108.16 KFR00073.1 - 2.1 8.4 6.4 3.3 7.8 0.7 2.8 1 1 2 3 3 3 0 Flagellar assembly protein FliH RNase_J_C PF17770.1 KFR00073.1 - 2.4 9.3 4.4 52 5.0 0.3 3.0 2 1 1 3 3 2 0 Ribonuclease J C-terminal domain DUF4665 PF15679.5 KFR00073.1 - 2.4 8.8 6.7 19 6.0 3.0 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) YojJ PF10372.9 KFR00073.1 - 2.5 8.3 10.4 18 5.5 0.1 4.4 2 1 2 4 4 4 0 Bacterial membrane-spanning protein N-terminus LUC7 PF03194.15 KFR00073.1 - 2.7 7.6 9.9 5.2 6.6 9.6 1.7 1 1 0 1 1 1 0 LUC7 N_terminus DUF4735 PF15882.5 KFR00073.1 - 2.8 7.3 6.1 2.7 7.4 1.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4735) Flg_hook PF02120.16 KFR00073.1 - 3 7.8 6.6 3.4 7.6 0.9 3.5 1 1 4 5 5 3 0 Flagellar hook-length control protein FliK DNA_primase_lrg PF04104.14 KFR00073.1 - 3.3 7.1 8.6 1.7e+02 1.4 8.3 2.5 1 1 1 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit Hemerythrin PF01814.23 KFR00073.1 - 3.6 8.2 10.4 15 6.2 4.6 2.8 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain Matrilin_ccoil PF10393.9 KFR00073.1 - 3.9 7.4 14.3 9.6 6.2 0.1 4.5 4 2 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF2203 PF09969.9 KFR00073.1 - 4.2 8.1 12.8 98 3.7 0.9 3.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) YabA PF06156.13 KFR00073.1 - 5.7 7.6 15.1 2.2e+02 2.5 0.1 3.4 1 1 1 2 2 2 0 Initiation control protein YabA MerR-DNA-bind PF09278.11 KFR00073.1 - 6.9 7.3 14.9 58 4.3 3.5 4.5 1 1 1 3 3 3 0 MerR, DNA binding MutS_IV PF05190.18 KFR00073.1 - 8.1 6.9 13.6 20 5.6 0.6 4.3 3 1 2 5 5 4 0 MutS family domain IV DUF2205 PF10224.9 KFR00073.1 - 8.6 6.4 13.9 1.4 9.0 2.4 4.2 1 1 3 4 4 4 0 Short coiled-coil protein ParcG PF10274.9 KFR00074.1 - 2.5 8.2 4.6 1 9.5 0.6 2.1 1 1 1 3 3 3 0 Parkin co-regulated protein ANF_receptor PF01094.28 KFR00075.1 - 5.5e-39 134.3 0.0 6.6e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Glyco_trans_4_4 PF13579.6 KFR00075.1 - 4.8 7.6 11.2 0.33 11.4 2.4 2.5 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain Cadherin PF00028.17 KFR00077.1 - 1.1e-84 279.0 6.1 2.1e-19 69.8 0.0 5.1 5 0 0 5 5 5 5 Cadherin domain Cadherin_2 PF08266.12 KFR00077.1 - 7.2e-08 32.2 0.0 0.014 15.2 0.0 4.1 4 0 0 4 4 4 2 Cadherin-like RET_CLD1 PF17756.1 KFR00077.1 - 0.0052 17.1 0.0 0.87 9.9 0.0 3.2 3 0 0 3 3 3 1 RET Cadherin like domain 1 Y_Y_Y PF07495.13 KFR00077.1 - 0.033 14.1 0.0 19 5.3 0.0 4.0 4 0 0 4 4 4 0 Y_Y_Y domain Cadherin_4 PF17803.1 KFR00077.1 - 0.049 14.3 0.6 0.049 14.3 0.6 4.3 5 0 0 5 5 5 0 Bacterial cadherin-like domain Big_9 PF17963.1 KFR00077.1 - 8 7.3 13.1 1.8 9.4 0.5 4.0 5 0 0 5 5 5 0 Bacterial Ig domain LRR_8 PF13855.6 KFR00101.1 - 8.9e-48 159.9 62.0 4.1e-13 48.9 2.2 10.4 3 3 9 12 12 12 11 Leucine rich repeat LRR_4 PF12799.7 KFR00101.1 - 3.3e-22 78.2 55.5 5.8e-05 23.4 0.2 11.7 4 3 7 13 13 13 10 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFR00101.1 - 1.4e-11 44.5 16.9 0.00019 21.4 0.6 5.1 4 2 2 6 6 6 4 BspA type Leucine rich repeat region (6 copies) LRR_11 PF18831.1 KFR00101.1 - 6e-06 25.7 1.7 5.9e-05 22.6 0.0 3.2 3 0 0 3 3 3 1 Leucine-rich repeat LRR_1 PF00560.33 KFR00101.1 - 8.7e-05 22.6 57.5 0.92 10.3 0.2 15.3 13 3 1 14 14 14 2 Leucine Rich Repeat LRR_9 PF14580.6 KFR00101.1 - 0.0018 17.8 18.8 1.3 8.5 0.6 5.1 2 2 3 5 5 5 4 Leucine-rich repeat DUF5365 PF17326.2 KFR00101.1 - 0.16 12.4 0.6 0.91 9.9 0.1 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5365) LRR_6 PF13516.6 KFR00101.1 - 9.7 6.5 54.3 1.7 8.9 0.2 13.3 17 0 0 17 17 17 0 Leucine Rich repeat Ion_trans_2 PF07885.16 KFR00103.1 - 7e-25 86.8 11.9 2.3e-16 59.5 4.5 2.4 2 0 0 2 2 2 2 Ion channel Pkinase_Tyr PF07714.17 KFR00105.1 - 2.1e-31 109.2 0.0 4.2e-31 108.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR00105.1 - 4.9e-26 91.7 0.0 1.3e-25 90.3 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain DUF3552 PF12072.8 KFR00105.1 - 0.19 11.2 14.6 0.35 10.2 14.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) OmpH PF03938.14 KFR00105.1 - 1.5 9.1 10.8 4.6 7.6 10.8 1.8 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3450 PF11932.8 KFR00105.1 - 3.3 7.0 10.8 6.3 6.0 10.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Methyltransf_31 PF13847.6 KFR00163.1 - 5.1e-12 45.8 0.0 8.4e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 KFR00163.1 - 7.5e-12 44.9 0.0 2.1e-10 40.1 0.0 2.3 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 KFR00163.1 - 8e-09 36.1 0.0 2.3e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFR00163.1 - 1.8e-05 24.4 0.0 3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KFR00163.1 - 0.00019 20.9 0.0 0.00041 19.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.12 KFR00163.1 - 0.003 18.2 0.0 0.0083 16.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KFR00163.1 - 0.0067 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFR00163.1 - 0.007 15.7 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 KFR00163.1 - 0.0078 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 KFR00163.1 - 0.026 13.9 0.1 0.04 13.3 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KFR00163.1 - 0.033 14.0 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KFR00163.1 - 0.046 14.5 0.0 0.088 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 KFR00163.1 - 0.064 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) AviRa PF11599.8 KFR00163.1 - 0.11 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Methyltransf_18 PF12847.7 KFR00163.1 - 0.15 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 KFR00163.1 - 0.21 10.7 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase DoxX_2 PF13564.6 KFR00164.1 - 1.5e-07 31.5 2.2 2.2e-07 30.9 2.2 1.2 1 0 0 1 1 1 1 DoxX-like family DUF4131 PF13567.6 KFR00164.1 - 0.0062 16.2 0.7 0.2 11.3 0.2 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4131) SID-1_RNA_chan PF13965.6 KFR00164.1 - 0.025 13.0 0.6 0.031 12.7 0.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 HCV_NS2 PF01538.18 KFR00164.1 - 0.086 12.5 1.8 0.11 12.1 1.8 1.2 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS2 Ac76 PF05814.11 KFR00164.1 - 0.6 10.2 4.3 0.14 12.2 0.8 1.7 2 0 0 2 2 2 0 Orf76 (Ac76) CENP-I PF07778.11 KFR00165.1 - 9e-280 928.7 15.7 1.2e-279 928.3 15.7 1.1 1 0 0 1 1 1 1 Mis6 OMS28_porin PF03532.13 KFR00165.1 - 0.36 10.0 1.4 0.82 8.9 1.4 1.5 1 0 0 1 1 1 0 OMS28 porin TPR_2 PF07719.17 KFR00166.1 - 9.1e-06 25.4 4.9 0.032 14.3 0.4 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFR00166.1 - 0.014 15.1 3.7 1.3 8.7 0.2 2.7 3 0 0 3 3 3 0 TPR repeat DUF1932 PF09130.11 KFR00166.1 - 0.23 11.5 3.4 0.32 11.0 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1932) TAFII55_N PF04658.13 KFR00167.1 - 3.9e-63 211.9 0.7 3.9e-63 211.9 0.7 2.2 2 1 0 2 2 2 1 TAFII55 protein conserved region Rep_4 PF05797.11 KFR00167.1 - 2.8 7.0 11.3 4.1 6.4 11.3 1.3 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Mg_trans_NIPA PF05653.14 KFR00168.1 - 1.1e-123 412.1 15.5 1.2e-123 411.9 15.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KFR00168.1 - 1.2e-07 31.9 5.1 1.2e-07 31.9 5.1 3.2 2 1 0 2 2 2 1 EamA-like transporter family COX6C PF02937.15 KFR00168.1 - 0.043 14.0 0.7 4.3 7.5 0.0 3.6 4 0 0 4 4 4 0 Cytochrome c oxidase subunit VIc zf-Tim10_DDP PF02953.15 KFR00169.1 - 9.3e-13 47.6 0.1 1.3e-12 47.2 0.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Pkinase_Tyr PF07714.17 KFR00170.1 - 5.3e-93 311.0 0.0 7.2e-93 310.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR00170.1 - 4.3e-47 160.7 0.0 6.6e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFR00170.1 - 3.9e-23 81.3 0.1 8.6e-23 80.2 0.1 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFR00170.1 - 5.3e-14 51.6 0.1 1.2e-13 50.4 0.1 1.7 1 0 0 1 1 1 1 SH3 domain BTK PF00779.19 KFR00170.1 - 3.3e-13 49.2 1.8 7.7e-13 48.0 1.8 1.7 1 0 0 1 1 1 1 BTK motif PH PF00169.29 KFR00170.1 - 7.2e-09 36.1 0.5 6.1e-08 33.1 0.1 2.3 2 0 0 2 2 2 1 PH domain SH3_9 PF14604.6 KFR00170.1 - 6.3e-08 32.4 0.1 1.4e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFR00170.1 - 3.5e-06 26.6 0.0 1.1e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFR00170.1 - 0.0003 21.0 0.1 0.0007 19.8 0.1 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain Kinase-like PF14531.6 KFR00170.1 - 0.00078 18.8 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_3 PF14593.6 KFR00170.1 - 0.0047 17.0 0.2 0.013 15.6 0.1 1.7 2 0 0 2 2 1 1 PH domain Haspin_kinase PF12330.8 KFR00170.1 - 0.013 14.4 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KFR00170.1 - 0.013 14.3 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SH3_10 PF17902.1 KFR00170.1 - 0.02 15.0 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 SH3 domain APH PF01636.23 KFR00170.1 - 0.042 13.8 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KFR00170.1 - 0.052 12.9 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L44 PF00935.19 KFR00171.1 - 4.4e-39 132.8 9.2 4.4e-39 132.8 9.2 1.7 1 1 1 2 2 2 1 Ribosomal protein L44 SVWC PF15430.6 KFR00171.1 - 0.04 14.2 1.8 0.14 12.5 0.1 2.0 2 0 0 2 2 2 0 Single domain von Willebrand factor type C Melibiase_2 PF16499.5 KFR00172.1 - 6e-136 452.2 0.4 8e-136 451.8 0.4 1.1 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_2_C PF17450.2 KFR00172.1 - 9.6e-28 96.3 0.0 1.7e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase PF02065.18 KFR00172.1 - 5.8e-06 25.5 0.0 1.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Melibiase Melibiase_C PF17801.1 KFR00172.1 - 0.00084 19.4 0.1 0.0023 18.0 0.0 1.8 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Neur_chan_LBD PF02931.23 KFR00173.1 - 8e-53 179.1 0.2 1e-52 178.7 0.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFR00173.1 - 3.2e-39 135.4 0.4 9.4e-34 117.5 0.1 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Myelin_PLP PF01275.19 KFR00174.1 - 1.1e-104 349.5 13.2 1.4e-104 349.2 13.2 1.1 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) Comm PF15957.5 KFR00174.1 - 0.087 13.2 0.2 0.22 11.9 0.2 1.6 1 0 0 1 1 1 0 Commissureless Ras PF00071.22 KFR00175.1 - 1e-56 191.0 0.0 1.4e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR00175.1 - 2.2e-30 105.3 0.0 3.4e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR00175.1 - 6e-10 38.9 0.0 6.8e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFR00175.1 - 2.8e-06 27.4 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFR00175.1 - 1.3e-05 24.7 0.0 2.2e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KFR00175.1 - 1.6e-05 24.9 0.1 0.012 15.5 0.1 2.5 2 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFR00175.1 - 0.00016 21.3 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 KFR00175.1 - 0.0066 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 KFR00175.1 - 0.03 14.7 0.1 0.051 14.0 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 KFR00175.1 - 0.087 12.0 1.5 2 7.5 0.1 2.6 1 1 1 2 2 2 0 G-protein alpha subunit FeoB_N PF02421.18 KFR00175.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Pribosyltran_N PF13793.6 KFR00176.1 - 1.7e-48 163.4 0.5 6e-48 161.6 0.1 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KFR00176.1 - 1.1e-44 152.6 2.5 7.8e-38 130.3 1.1 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KFR00176.1 - 1.3e-13 50.8 2.4 1.9e-13 50.2 0.5 2.1 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KFR00176.1 - 0.00038 20.0 0.1 0.00065 19.2 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Lar_N PF09861.9 KFR00176.1 - 0.12 11.5 1.0 0.39 9.8 0.0 2.2 3 0 0 3 3 3 0 Lactate racemase N-terminal domain FERM_N PF09379.10 KFR00177.1 - 6.3e-05 22.8 0.0 8.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 FERM N-terminal domain FERM_f0 PF16511.5 KFR00177.1 - 0.02 15.2 0.0 0.027 14.8 0.0 1.2 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM PIH1_CS PF18201.1 KFR00178.1 - 2.5e-12 47.0 0.0 3.1e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 PIH1 CS-like domain Nsp1_C PF05064.13 KFR00179.1 - 2.8e-40 136.7 6.7 7e-40 135.5 6.7 1.6 1 0 0 1 1 1 1 Nsp1-like C-terminal region DUF4164 PF13747.6 KFR00179.1 - 0.013 15.7 1.5 0.013 15.7 1.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Nup188_C PF18378.1 KFR00179.1 - 0.043 12.6 2.0 0.064 12.1 2.0 1.2 1 0 0 1 1 1 0 Nuclear pore protein NUP188 C-terminal domain YscO-like PF16789.5 KFR00179.1 - 0.52 10.3 11.4 0.35 10.9 1.5 2.1 2 0 0 2 2 2 0 YscO-like protein Filament PF00038.21 KFR00179.1 - 0.65 9.5 13.7 2 7.9 9.2 2.1 2 0 0 2 2 2 0 Intermediate filament protein GAS PF13851.6 KFR00179.1 - 0.74 9.1 14.4 1.8 7.8 14.4 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Carbpep_Y_N PF05388.11 KFR00179.1 - 0.74 10.4 3.4 1.2 9.7 1.0 2.4 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide RRM_1 PF00076.22 KFR00180.1 - 7.8e-07 28.8 0.0 1.8e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PMP22_Claudin PF00822.20 KFR00181.1 - 5.1e-23 81.8 6.2 6.2e-23 81.5 6.2 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFR00181.1 - 6.4e-07 29.3 7.9 1.4e-06 28.2 7.7 1.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF872 PF05915.12 KFR00181.1 - 0.027 14.6 0.2 0.027 14.6 0.2 1.9 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) TMEM37 PF15108.6 KFR00181.1 - 0.028 14.3 1.6 0.058 13.3 1.6 1.5 1 0 0 1 1 1 0 Voltage-dependent calcium channel gamma-like subunit protein family Amastin PF07344.11 KFR00181.1 - 0.18 11.7 6.8 0.23 11.3 6.1 1.7 1 1 1 2 2 2 0 Amastin surface glycoprotein ATP-synt_I PF03899.15 KFR00181.1 - 2.5 8.5 8.0 0.13 12.6 1.3 2.1 2 0 0 2 2 2 0 ATP synthase I chain Gla PF00594.20 KFR00182.1 - 5.9e-20 71.2 9.9 1.3e-19 70.1 9.9 1.6 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain T2SSM PF04612.12 KFR00182.1 - 0.053 13.6 0.1 0.078 13.0 0.1 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M SKG6 PF08693.10 KFR00182.1 - 4.3 6.8 8.9 8.8 5.8 8.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Miff PF05644.11 KFR00183.1 - 4e-17 62.8 0.0 4.8e-17 62.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial and peroxisomal fission factor Mff Ion_trans PF00520.31 KFR00184.1 - 2.6e-28 98.9 7.8 4.5e-28 98.1 7.8 1.4 1 0 0 1 1 1 1 Ion transport protein CLZ PF16526.5 KFR00184.1 - 7.5e-25 87.1 5.0 2.2e-24 85.6 5.0 1.9 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels cNMP_binding PF00027.29 KFR00184.1 - 3.9e-19 68.5 0.0 7.3e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KFR00184.1 - 0.052 13.5 7.1 0.16 11.9 7.1 1.9 1 1 0 1 1 1 0 Ion channel PIG-Y PF15159.6 KFR00184.1 - 4 8.4 6.3 5.5 8.0 0.0 3.0 2 1 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Neur_chan_memb PF02932.16 KFR00185.1 - 4.1e-37 128.5 8.8 7.1e-34 117.9 3.3 2.1 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFR00185.1 - 7.7e-37 126.8 1.6 1.1e-36 126.3 1.6 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.23 KFR00186.1 - 9.1e-48 162.5 0.0 1.4e-47 162.0 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFR00186.1 - 1.1e-37 130.4 7.5 2.5e-31 109.6 5.8 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region CytochromB561_N PF09786.9 KFR00186.1 - 0.052 12.6 1.5 0.069 12.1 1.5 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Neur_chan_memb PF02932.16 KFR00187.1 - 8.7e-53 179.8 0.0 1.4e-52 179.1 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFR00187.1 - 1.3e-36 126.1 0.1 1.8e-36 125.6 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain SOXp PF12336.8 KFR00188.1 - 1.6e-34 118.8 2.2 1.6e-34 118.8 2.2 2.5 3 0 0 3 3 3 1 SOX transcription factor HMG_box PF00505.19 KFR00188.1 - 1.2e-27 96.1 3.2 2.1e-27 95.4 2.4 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFR00188.1 - 1.7e-11 44.6 2.0 2.6e-11 43.9 2.0 1.3 1 0 0 1 1 1 1 HMG-box domain Peptidase_A17 PF05380.13 KFR00189.1 - 0.063 13.3 1.1 2.7 8.0 0.1 2.1 1 1 1 2 2 2 0 Pao retrotransposon peptidase LRR_8 PF13855.6 KFR00193.1 - 1.1e-49 166.0 39.8 4.6e-16 58.3 5.2 6.6 2 2 4 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 KFR00193.1 - 1.8e-22 79.0 45.0 5.1e-06 26.7 0.6 8.0 5 2 1 8 8 8 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFR00193.1 - 2.9e-17 62.8 0.3 4.2e-08 33.2 1.1 2.5 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFR00193.1 - 8.9e-08 31.8 15.1 0.0014 18.2 0.2 4.3 2 2 3 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.33 KFR00193.1 - 0.00011 22.2 36.7 0.19 12.4 0.0 10.7 10 2 0 10 10 10 2 Leucine Rich Repeat LRRNT PF01462.18 KFR00193.1 - 0.00044 19.8 3.3 0.00044 19.8 3.3 2.3 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain TPKR_C2 PF16920.5 KFR00193.1 - 0.0054 16.8 0.4 0.75 10.0 0.1 3.0 2 0 0 2 2 2 1 Tyrosine-protein kinase receptor C2 Ig-like domain COesterase PF00135.28 KFR00198.1 - 1.6e-68 231.9 0.0 1.7e-68 231.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family WH1 PF00568.23 KFR00208.1 - 3.5e-15 55.9 0.2 7e-15 54.9 0.2 1.5 1 0 0 1 1 1 1 WH1 domain TMF_TATA_bd PF12325.8 KFR00208.1 - 0.00068 19.8 19.9 0.00068 19.8 19.9 3.0 2 1 1 3 3 3 1 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 KFR00208.1 - 0.0021 18.1 16.5 0.1 12.7 8.3 3.2 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) GAS PF13851.6 KFR00208.1 - 0.0041 16.5 19.8 0.0041 16.5 19.8 2.6 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.9 KFR00208.1 - 0.0064 16.8 7.6 0.0064 16.8 7.6 3.4 2 1 2 4 4 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DMPK_coil PF08826.10 KFR00208.1 - 0.011 15.9 4.8 0.011 15.9 4.8 3.5 2 1 1 3 3 3 0 DMPK coiled coil domain like Nsp1_C PF05064.13 KFR00208.1 - 0.011 15.6 22.5 0.13 12.1 10.7 2.7 1 1 1 2 2 2 0 Nsp1-like C-terminal region SPT16 PF08644.11 KFR00208.1 - 0.022 15.0 10.0 0.073 13.3 4.7 2.4 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) FUSC PF04632.12 KFR00208.1 - 0.029 12.9 7.0 0.041 12.4 7.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DASH_Duo1 PF08651.10 KFR00208.1 - 0.055 13.3 0.9 0.055 13.3 0.9 3.3 3 0 0 3 3 3 0 DASH complex subunit Duo1 FPP PF05911.11 KFR00208.1 - 0.061 11.5 30.3 0.011 14.0 26.5 1.6 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil APG6_N PF17675.1 KFR00208.1 - 0.08 13.5 43.2 0.04 14.5 24.5 3.4 2 1 1 3 3 3 0 Apg6 coiled-coil region FAP206 PF12018.8 KFR00208.1 - 0.1 12.1 20.2 0.83 9.1 8.8 3.2 2 1 1 3 3 3 0 Domain of unknown function NPV_P10 PF05531.12 KFR00208.1 - 0.12 12.8 12.0 0.31 11.5 1.0 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Prominin PF05478.11 KFR00208.1 - 0.26 9.2 11.5 0.43 8.5 11.5 1.4 1 0 0 1 1 1 0 Prominin CALCOCO1 PF07888.11 KFR00208.1 - 0.28 10.0 34.4 0.015 14.2 27.0 2.4 2 1 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Laminin_II PF06009.12 KFR00208.1 - 0.37 10.8 21.1 0.096 12.7 9.2 2.9 2 1 1 3 3 3 0 Laminin Domain II HemX PF04375.14 KFR00208.1 - 0.37 10.0 24.5 0.32 10.2 11.6 2.4 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Fmp27_WPPW PF10359.9 KFR00208.1 - 0.43 9.4 17.2 0.95 8.2 16.7 1.7 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain IFT57 PF10498.9 KFR00208.1 - 0.45 9.4 30.1 1.7 7.6 5.1 2.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 FlaC_arch PF05377.11 KFR00208.1 - 0.62 10.5 17.7 7.6 7.0 2.0 4.5 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) DHR10 PF18595.1 KFR00208.1 - 0.67 10.0 44.1 0.67 10.0 22.6 3.9 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain Baculo_PEP_C PF04513.12 KFR00208.1 - 0.68 10.0 18.2 2.3 8.2 4.1 2.8 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.11 KFR00208.1 - 0.77 9.9 37.6 12 6.1 20.2 3.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 KFR00208.1 - 0.83 9.0 20.2 1.9 7.8 20.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Cluap1 PF10234.9 KFR00208.1 - 0.93 8.8 29.9 2.5 7.4 8.2 2.8 1 1 1 2 2 2 0 Clusterin-associated protein-1 Bacillus_HBL PF05791.11 KFR00208.1 - 0.94 9.3 20.2 0.28 11.0 5.4 2.8 2 1 1 3 3 2 0 Bacillus haemolytic enterotoxin (HBL) FapA PF03961.13 KFR00208.1 - 1.1 7.8 20.7 15 4.1 20.7 2.2 1 1 0 1 1 1 0 Flagellar Assembly Protein A DUF4164 PF13747.6 KFR00208.1 - 1.2 9.5 25.4 0.19 12.0 13.8 3.6 2 1 2 4 4 3 0 Domain of unknown function (DUF4164) DUF489 PF04356.12 KFR00208.1 - 1.2 9.1 11.3 0.49 10.4 6.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF489) DUF2968 PF11180.8 KFR00208.1 - 1.2 8.7 28.7 0.89 9.2 5.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) Fzo_mitofusin PF04799.13 KFR00208.1 - 1.4 8.5 20.9 1.4 8.4 12.6 2.9 1 1 2 3 3 3 0 fzo-like conserved region Leu_zip PF15294.6 KFR00208.1 - 1.4 8.3 28.8 0.44 10.0 24.5 2.2 2 1 0 2 2 2 0 Leucine zipper ADIP PF11559.8 KFR00208.1 - 1.5 8.9 37.1 0.21 11.7 14.4 3.1 2 1 1 3 3 2 0 Afadin- and alpha -actinin-Binding kleA_kleC PF17383.2 KFR00208.1 - 1.9 8.8 9.0 1.9 8.9 1.5 3.0 2 1 0 2 2 2 0 Uncharacterized KorC regulated protein A XhlA PF10779.9 KFR00208.1 - 2 8.7 19.5 0.53 10.5 3.4 3.7 2 1 0 3 3 3 0 Haemolysin XhlA CENP-F_leu_zip PF10473.9 KFR00208.1 - 2.1 8.3 38.9 0.24 11.4 28.1 3.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 KFR00208.1 - 2.2 8.1 35.9 0.55 10.1 5.4 4.6 3 2 3 6 6 5 0 Septum formation initiator Uso1_p115_C PF04871.13 KFR00208.1 - 2.3 8.6 37.0 0.59 10.5 20.4 3.1 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fib_alpha PF08702.10 KFR00208.1 - 2.4 8.3 21.7 1.7 8.8 12.0 2.7 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 KFR00208.1 - 2.7 8.3 11.9 17 5.8 2.9 3.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) HMMR_N PF15905.5 KFR00208.1 - 2.8 7.3 37.6 0.044 13.3 29.6 2.0 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal FTCD_C PF04961.12 KFR00208.1 - 3.1 7.5 10.6 1.8 8.3 4.2 2.5 2 1 0 2 2 2 0 Formiminotransferase-cyclodeaminase OmpH PF03938.14 KFR00208.1 - 3.3 8.0 33.5 0.19 12.1 19.0 3.5 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) ERM PF00769.19 KFR00208.1 - 3.6 7.3 37.8 3.6 7.3 22.1 3.2 2 1 1 3 3 3 0 Ezrin/radixin/moesin family DUF3450 PF11932.8 KFR00208.1 - 3.8 6.8 31.9 0.9 8.8 16.0 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF3450) AAA_13 PF13166.6 KFR00208.1 - 3.8 6.0 25.6 15 4.1 25.9 1.9 1 1 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.8 KFR00208.1 - 4.1 7.5 38.3 0.29 11.2 8.9 4.0 2 1 2 4 4 3 0 TATA element modulatory factor 1 DNA binding Prefoldin_2 PF01920.20 KFR00208.1 - 4.2 7.4 35.6 0.9 9.5 7.1 4.6 2 1 3 5 5 5 0 Prefoldin subunit YjcZ PF13990.6 KFR00208.1 - 4.2 6.6 11.3 4 6.7 9.7 1.6 1 1 0 1 1 1 0 YjcZ-like protein Syntaxin-6_N PF09177.11 KFR00208.1 - 4.3 7.9 19.9 2.6 8.6 10.6 3.4 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Spc42p PF11544.8 KFR00208.1 - 4.4 7.4 19.4 4.3 7.4 13.0 3.4 2 1 1 3 3 3 0 Spindle pole body component Spc42p Spc7 PF08317.11 KFR00208.1 - 4.7 6.0 36.3 0.72 8.7 28.4 2.6 2 1 0 2 2 2 0 Spc7 kinetochore protein Fez1 PF06818.15 KFR00208.1 - 4.8 7.6 31.6 4.4 7.7 6.1 2.9 1 1 2 3 3 3 0 Fez1 Golgin_A5 PF09787.9 KFR00208.1 - 4.9 6.5 33.7 0.071 12.6 17.9 2.3 2 1 1 3 3 3 0 Golgin subfamily A member 5 DUF1192 PF06698.11 KFR00208.1 - 5.3 7.2 13.9 0.52 10.4 3.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DUF3461 PF11944.8 KFR00208.1 - 5.4 7.2 18.5 0.091 12.9 5.4 2.5 2 1 1 3 3 2 0 Protein of unknown function (DUF3461) Lectin_N PF03954.14 KFR00208.1 - 5.5 6.7 17.5 13 5.5 7.2 3.3 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF5082 PF16888.5 KFR00208.1 - 6.1 7.1 23.8 2.4 8.4 14.4 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) Lebercilin PF15619.6 KFR00208.1 - 6.8 6.3 36.8 0.71 9.5 3.3 2.9 2 1 1 3 3 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF812 PF05667.11 KFR00208.1 - 7 5.4 30.6 15 4.3 30.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF2203 PF09969.9 KFR00208.1 - 7.7 7.3 18.5 15 6.4 4.8 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Phlebovirus_NSM PF07246.11 KFR00208.1 - 8.1 5.7 14.3 8.2 5.7 12.5 1.8 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M CENP-H PF05837.12 KFR00208.1 - 8.3 6.9 29.9 3.4 8.1 15.0 3.1 2 1 0 3 3 3 0 Centromere protein H (CENP-H) Spc24 PF08286.11 KFR00208.1 - 8.4 6.7 30.9 5.2 7.4 7.1 4.2 2 1 2 4 4 4 0 Spc24 subunit of Ndc80 DUF3584 PF12128.8 KFR00208.1 - 9.8 3.5 31.7 0.76 7.2 6.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) McrBC PF10117.9 KFR00216.1 - 0.076 12.1 0.0 0.66 9.1 0.0 2.0 2 0 0 2 2 2 0 McrBC 5-methylcytosine restriction system component DUF5087 PF17006.5 KFR00217.1 - 0.0011 18.6 0.3 0.002 17.7 0.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF5087) Hus1 PF04005.12 KFR00218.1 - 3.8e-81 272.4 0.2 4.2e-81 272.3 0.2 1.0 1 0 0 1 1 1 1 Hus1-like protein PTB PF08416.13 KFR00219.1 - 1.3e-40 138.6 0.0 2.2e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PTEN_C2 PF10409.9 KFR00219.1 - 6.5e-11 42.1 0.0 2.5e-10 40.2 0.0 2.0 2 1 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein SH2 PF00017.24 KFR00219.1 - 9.1e-10 38.5 0.0 2.3e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Y_phosphatase PF00102.27 KFR00219.1 - 0.0079 15.8 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFR00219.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.12 KFR00219.1 - 0.18 11.4 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Thyroglobulin_1 PF00086.18 KFR00221.1 - 3.4e-19 68.3 3.0 6.4e-19 67.4 3.0 1.5 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat DUF4829 PF16111.5 KFR00221.1 - 0.0051 17.6 0.1 0.0072 17.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4829) Guanylate_cyc PF00211.20 KFR00223.1 - 8.6e-129 426.4 0.8 2.2e-64 216.5 0.2 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 KFR00223.1 - 7e-34 117.7 3.4 7e-34 117.7 3.4 2.5 3 0 0 3 3 3 1 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF1053 PF06327.14 KFR00223.1 - 0.0067 17.0 0.6 0.013 16.1 0.6 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) HNOBA PF07701.14 KFR00223.1 - 0.083 12.3 1.6 0.39 10.1 0.3 2.2 2 0 0 2 2 2 0 Heme NO binding associated TBK1_ULD PF18396.1 KFR00223.1 - 0.084 12.8 0.2 0.52 10.3 0.0 2.4 3 0 0 3 3 3 0 TANK binding kinase 1 ubiquitin-like domain RAMP PF04901.13 KFR00225.1 - 4.2e-45 152.3 3.1 4.8e-45 152.1 3.1 1.0 1 0 0 1 1 1 1 Receptor activity modifying family DUF761 PF05553.11 KFR00225.1 - 0.12 11.9 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 Cotton fibre expressed protein Thioredoxin PF00085.20 KFR00226.1 - 1.4e-96 317.3 0.3 3.5e-31 107.2 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.6 KFR00226.1 - 8.4e-24 84.5 6.0 6.4e-16 58.8 0.5 4.7 4 1 1 5 5 5 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFR00226.1 - 2.5e-17 63.0 0.9 0.0024 18.2 0.0 6.4 4 2 2 6 6 6 3 Thioredoxin-like Thioredoxin_2 PF13098.6 KFR00226.1 - 4.7e-16 59.2 1.7 0.00071 20.0 0.0 4.6 3 1 0 3 3 3 3 Thioredoxin-like domain OST3_OST6 PF04756.13 KFR00226.1 - 1.8e-15 57.1 0.0 2.5e-05 23.8 0.0 3.2 3 0 0 3 3 3 3 OST3 / OST6 family, transporter family Calsequestrin PF01216.17 KFR00226.1 - 6.9e-13 48.4 3.9 8.6e-12 44.8 0.0 2.7 3 1 0 3 3 3 1 Calsequestrin Thioredoxin_7 PF13899.6 KFR00226.1 - 1.1e-10 41.5 0.0 0.054 13.7 0.0 3.8 3 0 0 3 3 3 3 Thioredoxin-like AhpC-TSA PF00578.21 KFR00226.1 - 5.8e-10 39.1 0.2 0.045 13.7 0.0 3.8 3 0 0 3 3 3 3 AhpC/TSA family TraF PF13728.6 KFR00226.1 - 2.1e-07 31.0 0.0 0.024 14.4 0.0 3.5 3 0 0 3 3 3 2 F plasmid transfer operon protein Redoxin PF08534.10 KFR00226.1 - 1.6e-06 27.9 0.8 0.78 9.4 0.0 3.8 4 0 0 4 4 4 3 Redoxin Thioredoxin_4 PF13462.6 KFR00226.1 - 5.7e-06 26.6 1.0 2 8.6 0.0 4.4 4 0 0 4 4 4 2 Thioredoxin HyaE PF07449.11 KFR00226.1 - 0.00017 21.5 0.0 3.3 7.7 0.0 3.7 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 KFR00226.1 - 0.0019 18.0 0.1 3.3 7.5 0.0 3.4 3 0 0 3 3 3 1 Thioredoxin DUF836 PF05768.14 KFR00226.1 - 0.0026 18.1 0.0 7 7.1 0.0 3.6 3 0 0 3 3 3 1 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 KFR00226.1 - 0.019 14.7 1.8 33 4.2 0.1 4.7 3 3 3 6 6 6 0 DSBA-like thioredoxin domain THB PF18362.1 KFR00226.1 - 0.29 10.8 1.1 15 5.3 0.1 3.3 3 0 0 3 3 3 0 Tri-helix bundle domain Thioredoxin_5 PF13743.6 KFR00226.1 - 1.6 8.3 5.8 56 3.3 0.1 4.5 4 1 1 5 5 5 0 Thioredoxin Glutaredoxin PF00462.24 KFR00226.1 - 2.8 8.2 7.8 9.2 6.6 0.0 4.1 3 2 0 3 3 3 0 Glutaredoxin PRC2_HTH_1 PF18118.1 KFR00227.1 - 2.1e-31 108.7 3.0 2.1e-31 108.7 3.0 2.7 2 0 0 2 2 2 1 Polycomb repressive complex 2 tri-helical domain SET PF00856.28 KFR00227.1 - 3.2e-18 66.7 6.0 6.5e-18 65.7 0.5 3.0 2 2 0 2 2 2 1 SET domain EZH2_WD-Binding PF11616.8 KFR00227.1 - 3e-16 59.2 3.5 7.3e-16 58.0 3.5 1.7 1 0 0 1 1 1 1 WD repeat binding protein EZH2 preSET_CXC PF18264.1 KFR00227.1 - 4.8e-12 46.1 15.6 4.8e-12 46.1 15.6 3.9 2 1 0 2 2 2 1 CXC domain Cullin PF00888.22 KFR00229.1 - 1.8e-199 664.4 21.7 1.8e-199 664.4 21.7 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 KFR00229.1 - 2.4e-28 97.9 2.8 1.7e-27 95.2 1.9 2.7 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF4980 PF16352.5 KFR00229.1 - 0.17 11.8 1.7 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4980) Laminin_G_2 PF02210.24 KFR00230.1 - 5.7e-46 156.2 0.0 2.8e-23 82.9 0.1 2.4 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 KFR00230.1 - 3.5e-30 104.9 0.0 7.6e-14 52.1 0.0 2.5 2 1 0 2 2 2 2 Laminin G domain Laminin_G_3 PF13385.6 KFR00230.1 - 0.00014 22.1 0.2 0.00062 19.9 0.0 2.1 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily Syndecan PF01034.20 KFR00230.1 - 0.016 15.1 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain hEGF PF12661.7 KFR00230.1 - 0.022 15.4 6.4 0.022 15.4 6.4 3.0 3 0 0 3 3 3 0 Human growth factor-like EGF MARVEL PF01284.23 KFR00230.1 - 0.098 12.7 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Membrane-associating domain Forkhead PF00250.18 KFR00250.1 - 6.5e-37 125.7 0.0 7.4e-37 125.5 0.0 1.0 1 0 0 1 1 1 1 Forkhead domain ADK PF00406.22 KFR00251.1 - 4.3e-33 114.5 0.0 5.6e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KFR00251.1 - 1.8e-27 96.4 0.0 2.4e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KFR00251.1 - 0.004 16.9 0.0 0.023 14.4 0.0 1.9 1 1 0 2 2 2 1 Thymidylate kinase AAA_18 PF13238.6 KFR00251.1 - 0.015 15.9 0.0 0.022 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain STIL_N PF15253.6 KFR00252.1 - 5.2e-209 694.2 0.0 7.7e-209 693.6 0.0 1.3 1 0 0 1 1 1 1 SCL-interrupting locus protein N-terminus HLH PF00010.26 KFR00253.1 - 2.1e-18 66.0 0.2 2.2e-18 65.9 0.2 1.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain COE1_HLH PF16423.5 KFR00253.1 - 0.0014 18.3 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Transcription factor COE1 helix-loop-helix domain PMBR PF09373.10 KFR00253.1 - 0.066 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Pseudomurein-binding repeat MAP17 PF15807.5 KFR00254.1 - 7.6e-37 126.3 0.3 9.1e-37 126.1 0.3 1.0 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Epiglycanin_C PF14654.6 KFR00254.1 - 0.0096 16.0 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Mucin, catalytic, TM and cytoplasmic tail region Baculo_F PF12259.8 KFR00254.1 - 0.034 12.7 0.5 0.042 12.4 0.5 1.1 1 0 0 1 1 1 0 Baculovirus F protein ECSCR PF15820.5 KFR00254.1 - 0.041 13.7 0.1 0.054 13.3 0.1 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator YajC PF02699.15 KFR00254.1 - 0.05 13.5 0.2 0.51 10.3 0.2 1.9 1 1 1 2 2 2 0 Preprotein translocase subunit DUF2500 PF10694.9 KFR00254.1 - 0.062 13.8 0.5 0.09 13.3 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) Gemini_mov PF01708.16 KFR00254.1 - 0.11 12.3 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Geminivirus putative movement protein Fer4_5 PF12801.7 KFR00254.1 - 0.11 12.5 2.7 0.2 11.6 2.7 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain EphA2_TM PF14575.6 KFR00254.1 - 0.19 12.6 0.6 0.33 11.9 0.6 1.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM52 PF14979.6 KFR00254.1 - 0.43 10.5 2.4 0.33 10.9 0.8 1.6 1 1 1 2 2 2 0 Transmembrane 52 p450 PF00067.22 KFR00255.1 - 1.4e-121 406.5 0.0 1.7e-121 406.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EPO_TPO PF00758.18 KFR00255.1 - 0.024 14.7 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin p450 PF00067.22 KFR00256.1 - 2.4e-124 415.6 0.0 2.8e-124 415.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BLOC1_2 PF10046.9 KFR00257.1 - 0.003 17.8 3.4 0.003 17.8 3.4 2.7 3 0 0 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 EF-hand_6 PF13405.6 KFR00257.1 - 0.0094 15.8 0.6 1.3 9.2 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 KFR00257.1 - 0.065 13.1 0.2 0.59 10.0 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain pair Lectin_N PF03954.14 KFR00257.1 - 0.092 12.5 12.4 0.11 12.3 0.8 3.2 2 2 1 3 3 3 0 Hepatic lectin, N-terminal domain RNA_pol_L PF01193.24 KFR00257.1 - 0.12 11.8 0.1 0.26 10.8 0.1 1.7 1 1 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain EF-hand_7 PF13499.6 KFR00257.1 - 0.12 12.8 1.1 0.39 11.2 0.3 2.3 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 KFR00257.1 - 0.16 11.5 0.2 2.4 7.8 0.1 2.5 2 0 0 2 2 2 0 EF hand ADIP PF11559.8 KFR00257.1 - 0.24 11.5 9.4 2.3 8.3 0.3 2.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 KFR00257.1 - 0.29 11.8 12.1 58 4.4 0.0 5.3 4 1 1 5 5 5 0 SlyX DUF641 PF04859.12 KFR00257.1 - 0.3 11.4 7.6 0.79 10.1 0.6 2.7 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) CC2-LZ PF16516.5 KFR00257.1 - 5 7.5 8.2 0.84 10.0 1.3 3.0 3 0 0 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator ATP11 PF06644.11 KFR00258.1 - 1.4e-49 169.4 0.7 1.8e-49 169.0 0.7 1.1 1 0 0 1 1 1 1 ATP11 protein Peptidase_M3_N PF08439.10 KFR00258.1 - 0.048 13.9 0.2 0.13 12.5 0.2 1.7 1 0 0 1 1 1 0 Oligopeptidase F Mob1_phocein PF03637.17 KFR00259.1 - 9.9e-78 260.0 0.5 1.1e-77 259.8 0.5 1.0 1 0 0 1 1 1 1 Mob1/phocein family Pkinase PF00069.25 KFR00260.1 - 6.2e-68 229.0 0.0 8.8e-68 228.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR00260.1 - 1e-29 103.7 0.0 1.5e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFR00260.1 - 1.4e-06 27.9 0.0 2.6e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RRN7 PF11781.8 KFR00260.1 - 0.00052 19.6 0.2 0.0016 18.1 0.2 1.9 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Pkinase_fungal PF17667.1 KFR00260.1 - 0.00068 18.5 0.0 0.001 17.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFR00260.1 - 0.003 17.5 0.1 1.7 8.5 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFR00260.1 - 0.012 14.5 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Homeodomain PF00046.29 KFR00261.1 - 5.2e-22 77.4 3.9 5.2e-22 77.4 3.9 2.2 2 0 0 2 2 2 1 Homeodomain OAR PF03826.17 KFR00261.1 - 8e-06 25.5 1.2 2.1e-05 24.2 1.2 1.7 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 KFR00261.1 - 0.009 15.9 0.1 0.027 14.3 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain Amidase PF01425.21 KFR00262.1 - 5e-111 371.8 0.0 5.9e-111 371.6 0.0 1.0 1 0 0 1 1 1 1 Amidase Amidase PF01425.21 KFR00263.1 - 4.5e-109 365.4 0.0 5.6e-109 365.1 0.0 1.1 1 0 0 1 1 1 1 Amidase Methyltr_RsmB-F PF01189.17 KFR00264.1 - 4.9e-32 111.2 0.0 6.2e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KFR00264.1 - 0.051 13.7 0.0 0.13 12.4 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase UCR_hinge PF02320.16 KFR00265.1 - 3.7e-19 68.7 8.2 4e-19 68.6 8.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein LRR_6 PF13516.6 KFR00266.1 - 0.06 13.4 8.2 1.6 9.0 0.1 4.8 5 0 0 5 5 5 0 Leucine Rich repeat SNF2_N PF00176.23 KFR00267.1 - 1.2e-58 198.6 0.0 1.9e-58 197.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFR00267.1 - 1.7e-16 60.6 0.0 3.5e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFR00267.1 - 1.4e-08 34.9 0.0 3.8e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFR00267.1 - 3.1e-07 30.3 0.0 9.3e-07 28.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KFR00267.1 - 1.7e-06 27.4 0.1 9.4e-06 25.0 0.1 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Rad54_N PF08658.10 KFR00267.1 - 2e-06 28.1 0.3 6.1e-05 23.3 0.2 2.5 2 0 0 2 2 2 1 Rad54 N terminal DUF2075 PF09848.9 KFR00267.1 - 0.17 11.1 0.0 0.53 9.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) GNT-I PF03071.15 KFR00268.1 - 8.3e-50 169.8 0.2 1.9e-49 168.6 0.2 1.5 1 1 0 1 1 1 1 GNT-I family ILEI PF15711.5 KFR00268.1 - 1.2e-24 86.5 0.0 2.8e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 Interleukin-like EMT inducer MGAT2 PF05060.14 KFR00268.1 - 0.037 13.1 0.0 1 8.3 0.0 2.3 2 0 0 2 2 2 0 N-acetylglucosaminyltransferase II (MGAT2) Tetraspanin PF00335.20 KFR00269.1 - 1.5e-45 155.7 13.0 1.7e-45 155.5 13.0 1.0 1 0 0 1 1 1 1 Tetraspanin family Kinocilin PF15033.6 KFR00269.1 - 0.033 13.8 0.1 0.033 13.8 0.1 2.8 2 1 1 3 3 3 0 Kinocilin protein DUF2981 PF11200.8 KFR00269.1 - 0.094 12.5 2.7 0.13 12.0 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) PI3K_P85_iSH2 PF16454.5 KFR00270.1 - 9e-64 213.9 20.7 1.3e-63 213.4 20.7 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SH2 PF00017.24 KFR00270.1 - 1.9e-41 140.0 0.0 1.3e-19 70.1 0.0 2.6 2 0 0 2 2 2 2 SH2 domain RhoGAP PF00620.27 KFR00270.1 - 7.6e-15 55.0 0.4 6.2e-14 52.1 0.0 2.5 2 1 1 3 3 3 1 RhoGAP domain SH3_1 PF00018.28 KFR00270.1 - 2.1e-06 27.2 0.2 0.00066 19.2 0.0 2.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFR00270.1 - 2.7e-06 27.2 0.4 8.7e-06 25.5 0.4 2.0 1 1 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFR00270.1 - 0.00051 19.7 0.0 0.0013 18.4 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Mod_r PF07200.13 KFR00270.1 - 0.11 12.6 14.0 0.12 12.5 5.2 2.5 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF5638 PF18688.1 KFR00270.1 - 0.45 10.9 7.5 0.056 13.8 1.6 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5638) Laminin_II PF06009.12 KFR00270.1 - 1.1 9.3 5.4 12 5.9 0.8 2.8 3 0 0 3 3 3 0 Laminin Domain II Transcrip_act PF04949.13 KFR00270.1 - 1.3 8.9 13.1 4.4 7.2 4.7 2.9 1 1 2 3 3 3 0 Transcriptional activator DUF1664 PF07889.12 KFR00270.1 - 3.4 7.7 5.3 2 8.5 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 KFR00270.1 - 4 6.9 7.8 6.3 6.3 7.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 KFR00270.1 - 4.9 6.4 6.4 7.1 5.9 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Folate_rec PF03024.14 KFR00272.1 - 2.5e-55 187.0 26.0 4.1e-55 186.3 26.0 1.3 1 0 0 1 1 1 1 Folate receptor family DUF1642 PF07852.11 KFR00272.1 - 0.0027 18.3 0.4 0.0062 17.1 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1642) TMEM206 PF15122.6 KFR00272.1 - 0.012 14.8 0.3 0.019 14.2 0.3 1.2 1 0 0 1 1 1 0 TMEM206 protein family Kelch_1 PF01344.25 KFR00273.1 - 1.8e-75 248.3 22.2 1.9e-15 56.1 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFR00273.1 - 4.3e-51 169.6 4.9 7.1e-10 38.8 0.0 6.3 1 1 5 6 6 6 6 Kelch motif BACK PF07707.15 KFR00273.1 - 4.5e-32 110.2 0.9 1.2e-31 108.8 0.5 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 KFR00273.1 - 1.2e-25 89.2 3.9 5.7e-05 23.3 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.6 KFR00273.1 - 3e-24 84.8 2.1 1.5e-05 24.9 0.0 6.3 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KFR00273.1 - 1.2e-21 75.8 13.8 1.6e-05 24.7 0.0 6.7 6 2 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 KFR00273.1 - 2.3e-09 37.0 8.6 0.042 13.8 0.0 5.9 6 0 0 6 6 6 3 Kelch motif BTB PF00651.31 KFR00273.1 - 0.0031 17.7 0.0 0.0065 16.7 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain SAM_3 PF18016.1 KFR00273.1 - 0.13 12.1 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF3429 PF11911.8 KFR00274.1 - 1.3e-36 126.1 10.3 1.6e-36 125.8 10.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Vasculin PF15337.6 KFR00275.1 - 7.8e-43 145.3 3.5 2.1e-42 143.9 3.5 1.8 1 0 0 1 1 1 1 Vascular protein family Vasculin-like 1 SHNi-TPR PF10516.9 KFR00276.1 - 4.9e-15 54.7 6.4 7.8e-15 54.0 1.5 3.0 3 0 0 3 3 3 1 SHNi-TPR TPR_12 PF13424.6 KFR00276.1 - 8.4e-10 38.8 11.7 2.6e-08 34.0 5.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFR00276.1 - 8.8e-09 34.8 10.7 0.019 15.0 0.3 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFR00276.1 - 2e-08 33.7 5.3 0.016 15.0 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFR00276.1 - 1.3e-05 25.1 7.2 0.11 12.8 0.3 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFR00276.1 - 0.0011 19.6 3.7 0.077 13.9 0.1 4.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFR00276.1 - 0.039 13.7 6.8 21 4.9 5.1 4.4 2 1 1 3 3 3 0 TPR repeat TPR_6 PF13174.6 KFR00276.1 - 0.26 12.0 7.0 8.3 7.3 0.3 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Aldo_ket_red PF00248.21 KFR00277.1 - 1.6e-52 178.5 0.1 2.9e-52 177.7 0.1 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family SLH PF00395.20 KFR00277.1 - 0.026 14.5 0.1 0.086 12.9 0.1 1.9 1 0 0 1 1 1 0 S-layer homology domain AhpC-TSA PF00578.21 KFR00278.1 - 2.5e-41 140.4 0.0 4.2e-41 139.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFR00278.1 - 1.4e-15 57.3 0.0 2e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KFR00278.1 - 5.4e-15 54.9 0.1 9.9e-15 54.1 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Endothelin PF00322.17 KFR00278.1 - 0.19 11.4 0.7 0.4 10.3 0.7 1.5 1 0 0 1 1 1 0 Endothelin family MMACHC PF16690.5 KFR00279.1 - 2.4e-100 334.7 0.1 2.7e-100 334.5 0.1 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family Pkinase PF00069.25 KFR00281.1 - 3.5e-41 141.3 0.0 4.2e-41 141.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR00281.1 - 4e-39 134.4 0.0 4.3e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFR00281.1 - 0.00054 18.9 0.0 0.00071 18.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFR00281.1 - 0.00057 19.3 0.1 0.001 18.5 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HhH-GPD PF00730.25 KFR00282.1 - 6e-22 78.1 0.0 1.1e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 KFR00282.1 - 3.8e-20 71.9 0.1 1e-19 70.6 0.1 1.7 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.23 KFR00282.1 - 4.4e-09 35.8 0.3 2e-08 33.7 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 KFR00282.1 - 0.046 14.1 4.8 0.046 14.1 4.8 2.3 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III SelP_N PF04592.14 KFR00283.1 - 8.6e-27 94.0 1.1 9.2e-27 94.0 1.1 1.0 1 0 0 1 1 1 1 Selenoprotein P, N terminal region SWIM PF04434.17 KFR00284.1 - 0.063 13.0 2.0 0.15 11.7 2.0 1.7 1 0 0 1 1 1 0 SWIM zinc finger URO-D PF01208.17 KFR00285.1 - 5.5e-134 446.7 0.0 6.2e-134 446.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) HECT PF00632.25 KFR00286.1 - 5.5e-53 180.4 0.0 8.3e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ANAPC10 PF03256.16 KFR00286.1 - 1e-13 51.3 0.1 1.7e-13 50.7 0.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 KFR00286.1 - 0.012 15.8 0.1 0.023 14.8 0.1 1.5 1 0 0 1 1 1 0 F5/8 type C domain HECT PF00632.25 KFR00288.1 - 1.4e-52 179.1 0.0 1.9e-52 178.7 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) NTP_transferase PF00483.23 KFR00289.1 - 2.8e-18 66.4 0.0 4.8e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KFR00289.1 - 7e-15 55.7 0.0 1.1e-14 55.1 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 KFR00289.1 - 9.6e-06 24.0 4.6 1.5e-05 23.4 2.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4954) Hexapep PF00132.24 KFR00289.1 - 0.00022 20.8 9.5 0.037 13.8 3.1 3.6 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 KFR00289.1 - 0.00047 19.2 0.7 0.00047 19.2 0.7 1.8 2 0 0 2 2 2 1 L-fucokinase IspD PF01128.19 KFR00289.1 - 0.0045 16.8 0.0 0.0073 16.1 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Patched PF02460.18 KFR00290.1 - 6.8e-73 246.1 12.5 1.9e-44 152.0 0.0 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 KFR00290.1 - 6.3e-46 156.0 5.5 6.3e-46 156.0 5.5 2.7 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 KFR00290.1 - 0.00043 19.3 4.3 0.00043 19.3 4.3 2.5 2 0 0 2 2 2 1 MMPL family BTB PF00651.31 KFR00291.1 - 1.8e-17 63.5 0.0 2.8e-16 59.7 0.0 2.2 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFR00291.1 - 3.6e-12 46.3 0.3 2.3e-11 43.7 0.1 2.2 2 1 1 3 3 3 1 BTB And C-terminal Kelch Tctex-1 PF03645.13 KFR00292.1 - 1.3e-18 67.1 0.0 1.4e-18 67.0 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family TetR_C_15 PF17918.1 KFR00292.1 - 0.11 13.3 0.0 0.17 12.6 0.0 1.4 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Pkinase PF00069.25 KFR00293.1 - 7.8e-67 225.4 0.0 1.4e-66 224.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain POLO_box PF00659.18 KFR00293.1 - 1.1e-36 124.8 2.7 7e-18 64.6 0.3 2.6 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_Tyr PF07714.17 KFR00293.1 - 7.7e-33 113.9 0.0 1.2e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR00293.1 - 6.1e-07 29.0 0.0 1.3e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFR00293.1 - 3.9e-05 22.6 0.0 8e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase PH_12 PF16457.5 KFR00293.1 - 0.097 13.2 0.3 1.9 9.0 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain DUF5105 PF17118.5 KFR00293.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5105) Kdo PF06293.14 KFR00293.1 - 0.77 9.1 3.2 0.71 9.2 0.3 2.0 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Bestrophin PF01062.21 KFR00294.1 - 4e-112 374.4 3.4 4.6e-112 374.2 3.4 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Ribosomal_S8e PF01201.22 KFR00295.1 - 3.8e-53 179.3 0.9 4.4e-53 179.1 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e ICAT PF06384.11 KFR00295.1 - 0.06 13.6 0.1 0.096 12.9 0.1 1.4 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT Kinesin PF00225.23 KFR00296.1 - 1.3e-94 316.9 0.1 1.3e-94 316.9 0.1 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFR00296.1 - 2.9e-16 59.7 0.1 4.9e-15 55.8 0.0 2.6 2 0 0 2 2 2 1 Microtubule binding DUF4685 PF15737.5 KFR00296.1 - 0.14 12.6 7.8 0.27 11.7 0.6 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4685) SIN1 PF05422.12 KFR00296.1 - 1.2 9.7 5.0 0.44 11.1 1.7 1.9 2 0 0 2 2 2 0 Stress-activated map kinase interacting protein 1 (SIN1) DUF5578 PF17741.1 KFR00297.1 - 3e-110 367.9 1.0 3.3e-110 367.7 1.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5578) Drf_GBD PF06371.13 KFR00297.1 - 0.058 13.0 0.1 0.1 12.2 0.1 1.5 1 1 0 1 1 1 0 Diaphanous GTPase-binding Domain DUF829 PF05705.14 KFR00298.1 - 4.6e-61 206.8 0.1 5.2e-61 206.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) RNF220 PF15926.5 KFR00299.1 - 1.5e-86 290.0 13.3 1.6e-49 168.8 1.3 3.0 2 1 1 3 3 3 2 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_2 PF13923.6 KFR00299.1 - 1.8e-13 50.1 11.4 1.8e-13 50.1 11.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFR00299.1 - 0.00012 21.8 7.5 0.00012 21.8 7.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFR00299.1 - 0.00065 19.6 8.0 0.00065 19.6 8.0 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFR00299.1 - 0.0012 18.6 10.0 0.0012 18.6 10.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFR00299.1 - 0.0028 17.9 10.6 0.0028 17.9 10.6 2.5 2 0 0 2 2 2 1 Ring finger domain Endonuclease_7 PF02945.15 KFR00299.1 - 0.0054 16.6 5.0 0.041 13.8 1.7 2.6 2 0 0 2 2 2 1 Recombination endonuclease VII zf-ribbon_3 PF13248.6 KFR00299.1 - 0.0064 15.9 0.9 3.2 7.3 0.2 3.0 2 0 0 2 2 2 2 zinc-ribbon domain Pox_A_type_inc PF04508.12 KFR00299.1 - 0.032 14.1 0.4 0.098 12.6 0.4 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat zf-RING_UBOX PF13445.6 KFR00299.1 - 0.19 11.8 14.3 0.077 13.0 8.7 2.6 2 0 0 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.6 KFR00299.1 - 0.25 11.2 12.9 0.21 11.5 6.6 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFR00299.1 - 0.51 10.4 5.4 0.2 11.7 2.6 1.7 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.7 KFR00299.1 - 2.5 8.2 6.3 36 4.5 4.5 3.0 2 1 0 2 2 2 0 Double zinc ribbon RNase_T PF00929.24 KFR00300.1 - 5.5e-42 144.1 0.0 6.6e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DMAP1 PF05499.12 KFR00302.1 - 9.2e-78 259.8 9.0 1.5e-77 259.1 9.0 1.4 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) SANT_DAMP1_like PF16282.5 KFR00302.1 - 8e-34 115.7 4.4 2.1e-33 114.3 4.4 1.8 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 ATP-synt_D PF01813.17 KFR00302.1 - 0.0048 16.7 3.3 0.0089 15.9 3.3 1.4 1 0 0 1 1 1 1 ATP synthase subunit D DUF2110 PF09883.9 KFR00302.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) FapA PF03961.13 KFR00302.1 - 4.8 5.7 8.3 4.5 5.8 5.6 1.9 1 1 0 2 2 2 0 Flagellar Assembly Protein A zf-C2H2 PF00096.26 KFR00303.1 - 1.2e-18 66.4 21.1 3.1e-06 27.3 4.1 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFR00303.1 - 7.4e-13 48.3 13.9 2.2e-07 31.0 4.8 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR00303.1 - 8.6e-11 41.7 19.3 0.00092 19.9 3.5 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFR00303.1 - 0.032 14.5 8.7 1.1 9.6 0.3 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFR00303.1 - 0.046 14.1 10.4 0.88 10.1 0.9 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFR00303.1 - 0.11 12.3 12.5 3.9 7.3 1.4 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KFR00303.1 - 0.14 12.5 8.0 8.7 6.7 8.0 2.3 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 KFR00303.1 - 0.5 11.0 8.8 0.58 10.8 1.3 2.9 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2HE PF16278.5 KFR00303.1 - 7.2 7.1 11.1 31 5.1 6.0 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger SNF PF00209.18 KFR00304.1 - 3.1e-143 478.2 22.7 3.5e-143 478.1 22.7 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Caveolin PF01146.17 KFR00304.1 - 0.19 11.7 4.9 0.42 10.6 4.9 1.5 1 0 0 1 1 1 0 Caveolin ATP-synt_C PF00137.21 KFR00305.1 - 2.6e-27 94.9 33.9 6.9e-14 51.9 12.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CrgA PF06781.12 KFR00305.1 - 0.32 11.1 0.1 0.32 11.1 0.1 2.5 2 1 2 4 4 4 0 Cell division protein CrgA PIRT PF15099.6 KFR00305.1 - 1.4 8.5 6.9 4.4 6.9 0.8 2.3 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family Diphthamide_syn PF01866.17 KFR00306.1 - 6.7e-85 285.2 0.0 8e-85 284.9 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Importin_rep_2 PF18786.1 KFR00307.1 - 1e-50 169.3 10.5 2.8e-26 91.1 1.1 3.0 3 0 0 3 3 3 2 Importin 13 repeat Importin_rep_3 PF18806.1 KFR00307.1 - 4e-36 122.9 0.0 1.5e-35 121.1 0.0 2.1 1 0 0 1 1 1 1 Importin 13 repeat Xpo1 PF08389.12 KFR00307.1 - 2.7e-28 98.9 8.5 1.3e-24 86.9 0.3 4.4 4 1 0 4 4 4 2 Exportin 1-like protein Importin_rep PF18773.1 KFR00307.1 - 2.1e-23 81.7 0.9 2.1e-23 81.7 0.9 2.3 3 0 0 3 3 3 1 Importin 13 repeat IBN_N PF03810.19 KFR00307.1 - 3.2e-09 36.6 1.4 1.4e-08 34.6 0.4 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain SLED PF12140.8 KFR00307.1 - 0.021 15.4 0.2 0.095 13.2 0.2 2.1 1 0 0 1 1 1 0 SLED domain Glyco_transf_29 PF00777.18 KFR00308.1 - 1.2e-69 234.7 0.0 1.5e-69 234.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) JmjC PF02373.22 KFR00309.1 - 4.8e-44 149.4 0.3 1.6e-43 147.8 0.1 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 KFR00309.1 - 6.7e-33 113.1 9.4 6.7e-33 113.1 9.4 2.6 2 0 0 2 2 2 1 PHD-zinc-finger like domain Tudor_2 PF18104.1 KFR00309.1 - 2.7e-32 110.1 5.2 1.5e-15 56.6 0.5 2.6 2 0 0 2 2 2 2 Jumonji domain-containing protein 2A Tudor domain zf-HC5HC2H PF13771.6 KFR00309.1 - 9.9e-15 54.6 5.5 9.9e-15 54.6 5.5 3.7 2 1 2 4 4 2 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KFR00309.1 - 1.1e-13 50.4 8.1 1.1e-13 50.4 8.1 3.1 3 0 0 3 3 3 1 PHD-finger PHD PF00628.29 KFR00309.1 - 1.3e-06 28.2 27.4 2.8e-06 27.1 5.5 3.7 3 0 0 3 3 3 2 PHD-finger LBR_tudor PF09465.10 KFR00309.1 - 1.5e-05 24.7 1.4 0.0051 16.6 0.1 2.6 2 0 0 2 2 2 2 Lamin-B receptor of TUDOR domain Tudor_3 PF18115.1 KFR00309.1 - 0.0037 17.1 0.7 3.5 7.5 0.1 3.1 2 1 1 3 3 3 2 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 KFR00309.1 - 0.0039 17.2 0.1 0.0092 16.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Rad9_Rad53_bind PF08605.10 KFR00309.1 - 0.051 13.8 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding 53-BP1_Tudor PF09038.10 KFR00309.1 - 0.096 12.6 0.2 0.79 9.7 0.2 2.2 1 1 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor Y_phosphatase PF00102.27 KFR00310.1 - 1.2e-167 555.2 1.3 1.4e-85 286.7 0.1 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 KFR00310.1 - 2.4e-110 361.1 29.4 1.9e-16 60.2 0.4 9.0 8 1 0 8 8 8 8 Fibronectin type III domain I-set PF07679.16 KFR00310.1 - 5.9e-44 148.1 0.0 4.8e-16 58.6 0.0 4.1 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR00310.1 - 9.4e-39 131.9 1.3 1.8e-12 47.6 0.0 5.3 5 0 0 5 5 3 3 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFR00310.1 - 8.9e-23 80.7 21.2 0.086 13.4 0.1 10.2 9 1 0 9 9 9 7 Purple acid Phosphatase, N-terminal domain Ig_2 PF13895.6 KFR00310.1 - 2.2e-21 75.9 0.1 1.1e-07 32.0 0.0 4.6 4 0 0 4 4 4 3 Immunoglobulin domain Interfer-bind PF09294.10 KFR00310.1 - 9.1e-15 54.9 0.7 0.081 13.3 0.0 7.4 8 0 0 8 8 7 3 Interferon-alpha/beta receptor, fibronectin type III ig PF00047.25 KFR00310.1 - 1.3e-14 54.1 0.0 0.0057 16.8 0.0 4.2 3 0 0 3 3 3 3 Immunoglobulin domain fn3_2 PF16893.5 KFR00310.1 - 5.5e-14 52.1 1.0 0.035 14.3 0.0 8.3 8 0 0 8 8 8 2 Fibronectin type III domain DSPc PF00782.20 KFR00310.1 - 1.3e-08 34.8 0.0 0.0037 17.1 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain V-set PF07686.17 KFR00310.1 - 1.7e-08 34.6 3.8 0.19 11.9 0.0 6.6 6 2 0 6 6 5 2 Immunoglobulin V-set domain Y_phosphatase3 PF13350.6 KFR00310.1 - 3.4e-08 33.7 0.1 0.014 15.3 0.0 3.2 3 0 0 3 3 3 2 Tyrosine phosphatase family C2-set_2 PF08205.12 KFR00310.1 - 8e-07 29.0 2.6 0.14 12.2 0.0 4.7 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain Y_Y_Y PF07495.13 KFR00310.1 - 2.3e-06 27.5 1.7 0.023 14.7 0.0 3.7 4 0 0 4 4 3 2 Y_Y_Y domain PTPlike_phytase PF14566.6 KFR00310.1 - 1.4e-05 25.3 0.1 0.019 15.1 0.0 3.2 3 0 0 3 3 2 1 Inositol hexakisphosphate Ig_5 PF16681.5 KFR00310.1 - 5.4e-05 23.5 0.0 0.1 13.0 0.0 3.8 3 0 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 KFR00310.1 - 0.00063 19.7 0.0 3.9 7.6 0.0 4.3 3 1 0 3 3 3 1 C17orf99 Ig domain DUF2369 PF10179.9 KFR00310.1 - 0.00069 20.0 0.1 19 5.7 0.0 5.9 5 1 1 6 6 6 0 Uncharacterised conserved protein (DUF2369) DUF4998 PF16389.5 KFR00310.1 - 0.0027 17.3 1.3 13 5.3 0.0 5.2 6 1 0 6 6 5 0 Domain of unknown function fn3_4 PF16794.5 KFR00310.1 - 0.0065 16.4 4.7 3.5 7.6 0.0 5.8 7 0 0 7 7 6 1 Fibronectin-III type domain Insulin_TMD PF17870.1 KFR00310.1 - 0.028 14.5 0.3 0.063 13.4 0.3 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment ICAM_N PF03921.14 KFR00310.1 - 0.11 12.2 0.0 0.46 10.2 0.0 2.1 1 0 0 1 1 1 0 Intercellular adhesion molecule (ICAM), N-terminal domain DUF3377 PF11857.8 KFR00310.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF1410 PF07198.11 KFR00310.1 - 0.67 10.5 2.8 7.9 7.1 1.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1410) TMEM154 PF15102.6 KFR00310.1 - 3.8 7.4 6.1 0.39 10.6 0.1 2.4 3 0 0 3 3 2 0 TMEM154 protein family AP_endonuc_2 PF01261.24 KFR00311.1 - 1.4e-16 60.6 0.0 2e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Sigma70_r4 PF04545.16 KFR00312.1 - 0.059 12.9 0.1 3.6 7.2 0.0 2.8 3 0 0 3 3 3 0 Sigma-70, region 4 Med8 PF10232.9 KFR00315.1 - 7.3e-81 271.2 0.2 8.4e-81 271.0 0.2 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 CSN4_RPN5_eIF3a PF18420.1 KFR00315.1 - 0.041 14.0 0.7 0.093 12.9 0.7 1.5 1 0 0 1 1 1 0 CSN4/RPN5/eIF3a helix turn helix domain Baculo_PEP_C PF04513.12 KFR00315.1 - 0.067 13.2 0.3 13 5.8 0.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ELO PF01151.18 KFR00316.1 - 3.2e-64 216.8 22.4 4e-64 216.5 22.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Spore_YhaL PF14147.6 KFR00316.1 - 0.32 10.7 0.1 0.32 10.7 0.1 2.5 3 0 0 3 3 3 0 Sporulation protein YhaL WD40 PF00400.32 KFR00317.1 - 5.4e-25 87.2 19.5 1.4e-05 25.8 0.2 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR00317.1 - 3.3e-19 69.0 9.8 1.8e-07 31.3 0.7 5.1 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFR00317.1 - 2.2e-05 24.5 1.0 0.099 12.5 0.1 2.7 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFR00317.1 - 0.00039 19.5 2.0 0.049 12.6 0.5 3.3 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ELYS-bb PF16687.5 KFR00317.1 - 0.066 11.8 0.0 0.12 10.9 0.0 1.4 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin Nup160 PF11715.8 KFR00317.1 - 0.13 10.8 2.2 5 5.7 0.1 2.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Pkinase_Tyr PF07714.17 KFR00318.1 - 3.4e-93 311.7 0.0 4.7e-93 311.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR00318.1 - 4.1e-42 144.4 0.0 7.4e-42 143.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 KFR00318.1 - 9e-29 99.7 1.0 2.4e-14 53.4 0.8 3.8 4 0 0 4 4 4 3 Fibronectin type III domain I-set PF07679.16 KFR00318.1 - 1.3e-08 34.8 0.1 0.0025 17.9 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.25 KFR00318.1 - 2.4e-07 30.8 0.1 0.0044 17.2 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 KFR00318.1 - 6.2e-07 29.9 0.1 0.063 13.9 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFR00318.1 - 5.9e-05 23.3 0.0 0.0035 17.6 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFR00318.1 - 0.00014 22.4 0.7 0.05 14.2 0.2 3.7 4 0 0 4 4 4 1 Purple acid Phosphatase, N-terminal domain hEGF PF12661.7 KFR00318.1 - 0.00015 22.3 7.5 0.00015 22.3 7.5 4.9 4 0 0 4 4 4 2 Human growth factor-like EGF EGF_2 PF07974.13 KFR00318.1 - 0.0011 19.2 68.7 0.0072 16.7 11.0 5.2 4 1 0 4 4 4 2 EGF-like domain V-set PF07686.17 KFR00318.1 - 0.0057 16.8 0.0 3.3 7.9 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin V-set domain Laminin_EGF PF00053.24 KFR00318.1 - 0.007 16.5 46.4 1 9.5 19.1 3.9 1 1 2 3 3 3 1 Laminin EGF domain Haspin_kinase PF12330.8 KFR00318.1 - 0.027 13.4 0.0 0.068 12.1 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KFR00318.1 - 0.035 12.9 0.0 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SusE PF14292.6 KFR00318.1 - 0.063 13.5 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 SusE outer membrane protein DUF4702 PF15774.5 KFR00318.1 - 0.088 11.7 0.0 0.2 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4702) APH PF01636.23 KFR00318.1 - 0.12 12.3 0.0 0.37 10.7 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family EGF PF00008.27 KFR00318.1 - 0.13 12.6 50.7 0.081 13.2 10.7 4.8 4 0 0 4 4 4 0 EGF-like domain DSL PF01414.19 KFR00318.1 - 2.5 8.5 51.2 4.6 7.6 13.7 3.7 3 0 0 3 3 3 0 Delta serrate ligand LRR19-TM PF15176.6 KFR00319.1 - 9.3e-33 112.3 0.0 1.5e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain LRR_8 PF13855.6 KFR00319.1 - 1.1e-23 82.7 37.2 5.3e-11 42.1 9.8 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFR00319.1 - 1.7e-06 28.3 18.4 0.0045 17.4 2.3 3.3 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFR00319.1 - 0.00031 20.3 0.3 0.00047 19.7 0.3 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 KFR00319.1 - 0.0026 18.0 15.7 5.1 8.0 0.6 5.6 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_5 PF13306.6 KFR00319.1 - 0.0088 16.0 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KFR00319.1 - 0.052 13.6 10.0 4.2 7.7 0.2 5.2 5 0 0 5 5 5 0 Leucine Rich repeat TMEM125 PF15109.6 KFR00320.1 - 1.4e-56 189.5 8.8 1.4e-56 189.5 8.8 2.0 2 0 0 2 2 2 1 TMEM125 protein family DUF4231 PF14015.6 KFR00320.1 - 0.049 14.1 6.9 2.8 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) MIG-14_Wnt-bd PF06664.12 KFR00320.1 - 0.43 9.8 5.1 0.53 9.5 0.8 2.1 1 1 0 2 2 2 0 Wnt-binding factor required for Wnt secretion UPF0182 PF03699.13 KFR00320.1 - 0.63 8.1 3.6 0.75 7.9 3.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Serpentine_r_xa PF03383.15 KFR00320.1 - 0.67 9.9 4.2 0.76 9.7 1.9 2.1 1 1 2 3 3 3 0 Caenorhabditis serpentine receptor-like protein, class xa Wzy_C PF04932.15 KFR00320.1 - 2.9 7.5 6.1 0.65 9.6 1.9 2.0 1 1 2 3 3 3 0 O-Antigen ligase DUF4282 PF14110.6 KFR00320.1 - 5.2 7.9 9.7 2 9.2 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) WD40 PF00400.32 KFR00321.1 - 3.4e-11 43.5 12.1 0.022 15.6 0.0 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat TMF_DNA_bd PF12329.8 KFR00321.1 - 0.0051 16.8 16.1 0.0051 16.8 16.1 7.3 4 1 3 7 7 7 2 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 KFR00321.1 - 0.01 15.9 5.6 0.01 15.9 5.6 6.4 2 2 2 5 5 5 0 Protein of unknown function (DUF1664) Ebp2 PF05890.12 KFR00322.1 - 9.3e-78 261.5 27.9 1.1e-77 261.3 27.9 1.0 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Atg14 PF10186.9 KFR00322.1 - 0.099 11.7 12.8 0.14 11.2 12.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HEPN_Apea PF18739.1 KFR00322.1 - 0.57 10.6 5.3 1.8 9.0 5.1 1.9 1 1 1 2 2 2 0 Apea-like HEPN O-antigen_lig PF13425.6 KFR00322.1 - 0.6 8.8 3.6 0.8 8.4 3.6 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein ALMT PF11744.8 KFR00322.1 - 1.4 7.6 8.3 1.7 7.4 8.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter GvpL_GvpF PF06386.11 KFR00322.1 - 1.5 8.7 9.1 0.43 10.5 5.3 2.0 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Cytochrom_B562 PF07361.11 KFR00322.1 - 3.7 8.2 16.3 4.3 8.1 14.0 2.1 1 1 1 2 2 2 0 Cytochrome b562 eIF3_N PF09440.10 KFR00322.1 - 7 7.1 10.9 4.6 7.7 8.2 2.0 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain FAM183 PF14886.6 KFR00323.1 - 8.9e-31 106.8 0.9 1e-30 106.6 0.9 1.1 1 0 0 1 1 1 1 FAM183A and FAM183B related PIF1 PF05970.14 KFR00324.1 - 1e-54 186.1 0.7 2.4e-52 178.3 0.7 2.3 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KFR00324.1 - 3e-09 36.9 0.0 4.8e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KFR00324.1 - 6.9e-05 22.6 0.4 0.00026 20.8 0.1 2.2 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KFR00324.1 - 0.00039 20.8 0.0 0.0012 19.2 0.0 1.8 2 1 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.14 KFR00324.1 - 0.00073 17.6 0.0 0.001 17.1 0.0 1.1 1 0 0 1 1 1 1 Helicase SH3_13 PF18335.1 KFR00324.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain ENOD40 PF08247.11 KFR00324.1 - 5.3 7.3 5.4 5.1 7.3 0.2 2.8 2 0 0 2 2 2 0 ENOD40 protein Glyco_transf_29 PF00777.18 KFR00326.1 - 9.5e-37 126.8 0.1 1.1e-36 126.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Peptidase_C13 PF01650.18 KFR00327.1 - 5.5e-37 127.7 0.0 1.1e-35 123.4 0.0 2.1 1 1 0 1 1 1 1 Peptidase C13 family ArgoMid PF16487.5 KFR00327.1 - 0.022 15.0 0.1 0.063 13.5 0.1 1.8 1 0 0 1 1 1 0 Mid domain of argonaute Peptidase_C14 PF00656.22 KFR00327.1 - 0.054 13.4 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Caspase domain ADK PF00406.22 KFR00328.1 - 2.1e-76 255.1 0.0 1e-39 136.0 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 KFR00328.1 - 2.2e-54 183.6 0.1 1.3e-26 93.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KFR00328.1 - 6.8e-20 71.9 0.0 6e-08 33.3 0.0 3.3 2 1 1 3 3 3 3 AAA domain AAA_33 PF13671.6 KFR00328.1 - 1.4e-10 41.5 0.1 0.00017 21.8 0.2 3.4 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KFR00328.1 - 1.5e-06 27.7 0.1 0.0092 15.3 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin Cytidylate_kin PF02224.18 KFR00328.1 - 1.7e-06 27.9 0.6 0.31 10.7 0.1 3.2 2 1 0 3 3 3 2 Cytidylate kinase Hydin_ADK PF17213.3 KFR00328.1 - 3.7e-06 27.3 0.0 0.065 13.5 0.0 2.4 2 0 0 2 2 2 2 Hydin Adenylate kinase-like domain Thymidylate_kin PF02223.17 KFR00328.1 - 0.00012 21.8 3.8 0.038 13.7 0.1 3.9 4 0 0 4 4 4 1 Thymidylate kinase AAA_16 PF13191.6 KFR00328.1 - 0.00044 20.7 0.2 0.79 10.1 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_19 PF13245.6 KFR00328.1 - 0.00054 20.3 0.1 0.86 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain dNK PF01712.19 KFR00328.1 - 0.00075 19.4 0.2 0.096 12.5 0.0 3.3 3 0 0 3 3 3 1 Deoxynucleoside kinase AAA PF00004.29 KFR00328.1 - 0.0017 18.8 0.2 1.9 8.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KFR00328.1 - 0.0018 18.5 0.2 0.32 11.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFR00328.1 - 0.0035 17.6 0.1 3.1 8.1 0.1 3.0 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 KFR00328.1 - 0.0036 16.7 0.7 1.2 8.4 0.1 2.7 3 0 0 3 3 3 2 KaiC Ploopntkinase3 PF18751.1 KFR00328.1 - 0.0043 17.0 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 2 P-loop Nucleotide Kinase3 CobU PF02283.16 KFR00328.1 - 0.022 14.3 0.2 8.8 5.9 0.0 3.5 4 0 0 4 4 4 0 Cobinamide kinase / cobinamide phosphate guanyltransferase SKI PF01202.22 KFR00328.1 - 0.086 13.0 0.2 42 4.2 0.0 3.8 4 0 0 4 4 4 0 Shikimate kinase SRP54 PF00448.22 KFR00328.1 - 0.12 12.0 0.3 8.2 6.0 0.0 2.8 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain DUF2075 PF09848.9 KFR00328.1 - 0.17 11.1 0.7 6.3 5.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Myb_DNA-binding PF00249.31 KFR00329.1 - 4e-10 39.7 0.5 1.1e-09 38.3 0.5 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFR00329.1 - 8.2e-06 26.0 0.1 2.6e-05 24.4 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 KFR00329.1 - 1.2e-05 25.0 7.8 1.2e-05 25.0 7.8 2.2 2 0 0 2 2 2 1 Zinc finger, ZZ type UCH PF00443.29 KFR00330.1 - 2.2e-63 214.2 0.0 2.2e-62 210.9 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KFR00330.1 - 1.4e-24 86.5 0.2 1.2e-13 51.4 0.0 3.3 3 0 0 3 3 3 2 DUSP domain UCH_1 PF13423.6 KFR00330.1 - 6.7e-19 68.6 8.5 1.1e-18 67.9 1.9 3.9 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFR00330.1 - 1.5e-11 44.4 4.9 1.5e-11 44.4 4.9 3.4 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein U71 PF17474.2 KFR00330.1 - 0.53 10.3 5.0 2.6 8.0 0.1 3.0 3 0 0 3 3 3 0 Tegument protein UL11 homolog Miga PF10265.9 KFR00331.1 - 8.1e-256 850.2 4.0 9.2e-256 850.0 4.0 1.0 1 0 0 1 1 1 1 Mitoguardin I-set PF07679.16 KFR00332.1 - 1.2e-18 67.0 0.0 3.1e-18 65.6 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR00332.1 - 2.2e-10 41.0 0.0 6e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFR00332.1 - 5.6e-07 29.6 0.1 2.2e-06 27.7 0.1 2.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFR00332.1 - 0.0032 17.8 0.0 0.0056 17.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain KH_1 PF00013.29 KFR00333.1 - 6.4e-65 214.9 17.1 2.3e-18 65.8 0.1 4.5 4 1 0 4 4 4 4 KH domain KH_2 PF07650.17 KFR00333.1 - 1.5e-18 66.4 10.3 3.6e-05 23.5 0.3 4.3 4 0 0 4 4 4 4 KH domain DUF1897 PF09005.10 KFR00333.1 - 7e-13 47.8 20.7 1.2e-06 27.9 6.9 3.9 3 0 0 3 3 3 3 Domain of unknown function (DUF1897) KH_4 PF13083.6 KFR00333.1 - 7.4e-06 25.7 8.4 0.18 11.7 0.1 4.2 4 0 0 4 4 4 3 KH domain Secretin_N PF03958.17 KFR00333.1 - 0.0074 16.7 4.2 0.11 12.9 0.8 3.4 3 2 1 4 4 4 1 Bacterial type II/III secretion system short domain KH_5 PF13184.6 KFR00333.1 - 1 9.5 9.6 4.9 7.3 0.1 3.6 4 0 0 4 4 4 0 NusA-like KH domain DnaJ_C PF01556.18 KFR00334.1 - 1.9e-44 151.3 0.2 2.5e-44 150.9 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFR00334.1 - 1.1e-28 99.2 3.1 1.9e-28 98.3 3.1 1.5 1 0 0 1 1 1 1 DnaJ domain PDZ PF00595.24 KFR00335.1 - 1.2e-07 32.0 0.1 2.1e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFR00335.1 - 0.0049 16.7 0.0 0.0098 15.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFR00335.1 - 0.03 14.6 0.0 0.078 13.3 0.0 1.7 2 0 0 2 2 2 0 PDZ domain Vitellogenin_N PF01347.22 KFR00336.1 - 1.4e-151 506.0 0.5 1.4e-151 506.0 0.5 3.3 2 1 0 2 2 2 1 Lipoprotein amino terminal region DUF1944 PF09175.10 KFR00336.1 - 1.1e-58 197.8 0.7 2.4e-58 196.7 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1944) DUF1943 PF09172.11 KFR00336.1 - 7.7e-58 196.2 0.2 7.7e-58 196.2 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1943) VWD PF00094.25 KFR00336.1 - 7.2e-25 88.1 1.8 7.2e-25 88.1 1.8 2.5 2 0 0 2 2 2 1 von Willebrand factor type D domain 7tm_2 PF00002.24 KFR00337.1 - 2.8e-58 197.1 27.9 4.9e-58 196.3 27.9 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GAIN PF16489.5 KFR00337.1 - 1.6e-43 148.6 4.8 2.1e-43 148.2 4.8 1.1 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain EGF_CA PF07645.15 KFR00337.1 - 9.9e-16 57.7 47.0 1.2e-08 35.0 10.5 3.8 3 1 0 3 3 3 3 Calcium-binding EGF domain GPS PF01825.21 KFR00337.1 - 2.7e-15 56.6 6.6 2.7e-15 56.6 6.6 2.4 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif cEGF PF12662.7 KFR00337.1 - 1e-11 44.5 23.4 5.9e-08 32.5 1.1 3.8 3 0 0 3 3 3 2 Complement Clr-like EGF-like EGF_3 PF12947.7 KFR00337.1 - 4.3e-11 42.8 56.1 1.4e-05 25.2 7.7 5.1 5 0 0 5 5 5 3 EGF domain Plasmod_Pvs28 PF06247.11 KFR00337.1 - 0.00035 20.8 47.4 0.0053 17.0 5.2 5.0 5 0 0 5 5 4 3 Pvs28 EGF domain FXa_inhibition PF14670.6 KFR00337.1 - 0.00077 19.7 5.7 0.00077 19.7 5.7 4.1 3 1 1 4 4 4 2 Coagulation Factor Xa inhibitory site hEGF PF12661.7 KFR00337.1 - 0.00096 19.7 5.6 0.00096 19.7 5.6 5.0 6 0 0 6 6 4 2 Human growth factor-like EGF EGF PF00008.27 KFR00337.1 - 0.0038 17.5 50.9 0.017 15.5 6.7 5.1 5 2 0 5 5 4 3 EGF-like domain DUF2371 PF10177.9 KFR00337.1 - 0.23 11.6 1.9 0.51 10.5 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Pox_A14 PF05767.12 KFR00337.1 - 1.8 8.8 9.4 0.74 10.0 3.4 2.8 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Latrophilin PF02354.16 KFR00339.1 - 7.5e-174 578.2 13.4 1e-173 577.7 13.4 1.2 1 0 0 1 1 1 1 Latrophilin Cytoplasmic C-terminal region OLF PF02191.16 KFR00339.1 - 3.2e-85 285.7 5.3 6.1e-85 284.7 5.3 1.5 1 0 0 1 1 1 1 Olfactomedin-like domain 7tm_2 PF00002.24 KFR00339.1 - 1.9e-68 230.4 17.9 2.8e-68 229.9 17.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GAIN PF16489.5 KFR00339.1 - 2.3e-54 184.0 0.6 3.5e-54 183.4 0.6 1.3 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Gal_Lectin PF02140.18 KFR00339.1 - 1.1e-23 83.5 0.7 3e-23 82.1 0.7 1.8 1 0 0 1 1 1 1 Galactose binding lectin domain GPS PF01825.21 KFR00339.1 - 2.8e-15 56.5 5.8 8.1e-15 55.1 5.8 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif HRM PF02793.22 KFR00339.1 - 4.9e-09 36.4 1.6 1.3e-08 35.0 1.6 1.8 1 0 0 1 1 1 1 Hormone receptor domain DUF5074 PF16819.5 KFR00339.1 - 0.45 10.6 5.2 0.92 9.6 0.8 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF5074) zf-C2HCIx2C PF10782.9 KFR00339.1 - 0.91 9.5 4.8 2.1 8.3 4.8 1.6 1 0 0 1 1 1 0 Zinc-finger TTL PF03133.15 KFR00340.1 - 3.1e-79 266.2 0.4 3.1e-79 266.2 0.4 2.0 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 KFR00340.1 - 2.2e-07 30.4 0.0 0.018 14.3 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 KFR00340.1 - 6e-07 29.0 3.6 0.001 18.4 0.0 3.4 3 1 1 4 4 4 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 KFR00340.1 - 0.00078 19.5 0.0 0.0032 17.5 0.0 2.1 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KFR00340.1 - 0.096 12.3 0.0 2.9 7.5 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATP-grasp domain HNF_C PF09354.10 KFR00340.1 - 1 10.4 4.6 1.5 9.9 0.0 3.3 3 1 0 3 3 3 0 HNF3 C-terminal domain GTP-bdg_M PF16360.5 KFR00340.1 - 1.8 9.3 13.6 0.039 14.6 4.6 2.8 3 0 0 3 3 3 0 GTP-binding GTPase Middle Region Pkinase PF00069.25 KFR00341.1 - 2.3e-73 246.8 0.0 2.9e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR00341.1 - 5.6e-35 120.9 0.0 7.8e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR00341.1 - 1.2e-08 34.7 0.0 2.8e-08 33.4 0.0 1.5 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFR00341.1 - 0.021 13.8 0.3 0.053 12.5 0.1 1.6 1 1 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 KFR00341.1 - 0.066 13.1 0.1 1.9 8.3 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family SAM_1 PF00536.30 KFR00342.1 - 8.6e-10 38.9 0.0 1.1e-09 38.6 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFR00342.1 - 4.8e-05 23.4 0.0 7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFR00342.1 - 8.2e-05 22.5 0.0 9.4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Uricase PF01014.18 KFR00343.1 - 7.1e-46 155.7 0.0 4.1e-26 91.8 0.1 2.0 2 0 0 2 2 2 2 Uricase zf-SCNM1 PF15803.5 KFR00343.1 - 0.059 13.0 0.2 0.17 11.5 0.2 1.8 1 0 0 1 1 1 0 Zinc-finger of sodium channel modifier 1 DNase_II PF03265.15 KFR00344.1 - 4.1e-110 368.1 0.3 4.7e-110 367.9 0.3 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II Brix PF04427.18 KFR00345.1 - 2.6e-25 89.7 0.2 3.3e-25 89.3 0.2 1.1 1 0 0 1 1 1 1 Brix domain G-gamma PF00631.22 KFR00346.1 - 3.9e-09 36.4 0.0 4.1e-09 36.3 0.0 1.0 1 0 0 1 1 1 1 GGL domain SPATA1_C PF15743.5 KFR00347.1 - 4e-52 176.3 28.0 4e-52 176.3 28.0 2.2 2 0 0 2 2 2 1 Spermatogenesis-associated C-terminus Glyco_hydro_18 PF00704.28 KFR00348.1 - 7.6e-34 117.8 0.4 9.4e-34 117.5 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Vitellogenin_N PF01347.22 KFR00349.1 - 4.5e-155 517.6 0.0 4.5e-155 517.6 0.0 3.0 2 1 0 2 2 2 1 Lipoprotein amino terminal region DUF1943 PF09172.11 KFR00349.1 - 3.4e-64 217.0 0.0 3.4e-64 217.0 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF1943) DUF1944 PF09175.10 KFR00349.1 - 1.2e-63 213.9 0.0 2.2e-63 213.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1944) VWD PF00094.25 KFR00349.1 - 2.8e-22 79.7 2.0 9.2e-22 78.0 0.0 2.8 3 0 0 3 3 3 1 von Willebrand factor type D domain HEAT_2 PF13646.6 KFR00349.1 - 0.012 15.9 0.0 6.8 7.2 0.0 3.2 2 1 0 2 2 2 0 HEAT repeats TonB_C PF03544.14 KFR00349.1 - 0.035 14.6 0.0 0.1 13.1 0.0 1.8 1 0 0 1 1 1 0 Gram-negative bacterial TonB protein C-terminal 7tm_1 PF00001.21 KFR00350.1 - 6.1e-35 120.8 23.5 1e-34 120.1 23.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFR00350.1 - 0.0025 17.6 16.9 0.0089 15.8 16.9 1.9 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFR00350.1 - 0.0028 17.3 23.7 0.0053 16.4 22.1 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx TMEM192 PF14802.6 KFR00350.1 - 0.36 9.9 5.0 0.11 11.6 1.7 1.7 2 0 0 2 2 2 0 TMEM192 family PKD_channel PF08016.12 KFR00351.1 - 2e-11 43.2 10.1 3.1e-11 42.6 10.1 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KFR00351.1 - 0.00025 20.4 18.7 0.00053 19.3 18.7 1.5 1 1 0 1 1 1 1 Ion transport protein DUF4522 PF15022.6 KFR00351.1 - 0.033 14.4 0.1 0.084 13.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4522) PKD_channel PF08016.12 KFR00352.1 - 6.9e-11 41.5 15.2 1e-10 40.9 14.9 1.5 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KFR00352.1 - 0.0028 16.9 25.0 0.013 14.8 25.0 2.0 1 1 0 1 1 1 1 Ion transport protein WD40 PF00400.32 KFR00353.1 - 2.9e-05 24.7 5.6 0.25 12.3 0.0 5.2 5 1 0 5 5 5 2 WD domain, G-beta repeat Xol-1_GHMP-like PF09109.10 KFR00353.1 - 0.082 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Switch protein XOL-1, GHMP-like DUF4660 PF15559.6 KFR00354.1 - 2.1e-10 40.8 5.7 2.1e-10 40.8 5.7 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4660) CARD PF00619.21 KFR00355.1 - 4.3e-16 58.7 0.3 6.7e-16 58.1 0.3 1.2 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 KFR00355.1 - 0.0025 17.8 0.1 0.0042 17.1 0.1 1.4 1 0 0 1 1 1 1 Caspase recruitment domain TetR_C_8 PF14278.6 KFR00355.1 - 0.084 13.0 0.1 0.22 11.7 0.0 1.7 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region Amidinotransf PF02274.17 KFR00356.1 - 9.2e-05 21.7 0.0 0.0002 20.6 0.0 1.6 1 1 0 1 1 1 1 Amidinotransferase TTRAP PF14203.6 KFR00356.1 - 0.73 9.9 2.6 2.1 8.4 0.0 2.6 3 0 0 3 3 3 0 Putative tranposon-transfer assisting protein Cys_knot PF00007.22 KFR00357.1 - 1.4e-16 60.6 13.5 1.4e-16 60.6 13.5 3.2 4 0 0 4 4 4 1 Cystine-knot domain VWC PF00093.18 KFR00357.1 - 2.1e-10 40.7 12.5 2.1e-10 40.7 12.5 5.0 3 1 0 3 3 3 1 von Willebrand factor type C domain TSP_1 PF00090.19 KFR00357.1 - 4.1e-05 23.7 7.4 4.1e-05 23.7 7.4 4.2 5 1 0 5 5 5 1 Thrombospondin type 1 domain Sclerostin PF05463.11 KFR00357.1 - 0.00019 21.2 4.9 0.00035 20.3 4.9 1.5 1 0 0 1 1 1 1 Sclerostin (SOST) zf-HIT PF04438.16 KFR00358.1 - 4e-05 23.4 12.5 4e-05 23.4 12.5 1.9 3 0 0 3 3 3 1 HIT zinc finger zf-B_box PF00643.24 KFR00358.1 - 1.5 9.0 9.3 3.9 7.7 9.3 1.7 1 0 0 1 1 1 0 B-box zinc finger CLCA PF08434.11 KFR00360.1 - 1.8e-109 365.2 7.3 2.5e-109 364.7 7.3 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel N terminal VWA PF00092.28 KFR00360.1 - 2.3e-12 47.5 0.0 4.8e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFR00360.1 - 7.5e-11 42.6 0.0 1.5e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KFR00360.1 - 0.0098 15.3 2.3 0.017 14.5 0.2 2.2 2 1 0 2 2 2 1 VWA domain containing CoxE-like protein BAR PF03114.18 KFR00361.1 - 9.9e-70 234.9 4.4 1.4e-69 234.4 4.4 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 KFR00361.1 - 8.4e-11 41.6 0.0 2.3e-10 40.1 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain BAR_2 PF10455.9 KFR00361.1 - 2.5e-09 36.7 0.1 3.9e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 KFR00361.1 - 3.7e-08 33.4 1.7 5.1e-08 32.9 1.7 1.3 1 1 0 1 1 1 1 BAR domain of APPL family SH3_2 PF07653.17 KFR00361.1 - 7.8e-08 31.9 0.0 1.6e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFR00361.1 - 8e-08 31.8 0.0 1.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Sds3 PF08598.11 KFR00361.1 - 0.034 14.1 0.6 0.058 13.4 0.6 1.3 1 0 0 1 1 1 0 Sds3-like Sep15_SelM PF08806.11 KFR00362.1 - 3e-12 46.5 0.0 3.2e-12 46.4 0.0 1.0 1 0 0 1 1 1 1 Sep15/SelM redox domain Sulfotransfer_2 PF03567.14 KFR00364.1 - 2.4e-41 142.3 0.6 2.8e-41 142.1 0.6 1.1 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 KFR00364.1 - 0.00036 19.5 0.0 0.00051 19.0 0.0 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_1 PF00685.27 KFR00364.1 - 0.0061 16.1 0.0 0.0092 15.5 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain RAP PF08373.10 KFR00364.1 - 0.05 13.7 1.1 0.18 11.9 0.0 2.5 3 0 0 3 3 3 0 RAP domain DICT PF10069.9 KFR00364.1 - 0.088 12.6 0.6 1.2 9.0 0.1 2.3 2 0 0 2 2 2 0 Sensory domain in DIguanylate Cyclases and Two-component system DUF2129 PF09902.9 KFR00364.1 - 0.19 11.8 1.5 0.31 11.1 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2129) LIM PF00412.22 KFR00365.1 - 1.3e-13 50.9 0.2 1.7e-13 50.6 0.2 1.1 1 0 0 1 1 1 1 LIM domain Pkinase PF00069.25 KFR00367.1 - 1.2e-60 205.2 0.0 2.3e-60 204.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR00367.1 - 9.1e-39 133.3 0.0 1.3e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 KFR00367.1 - 7.2e-33 112.5 16.5 3.7e-17 62.2 8.0 2.4 2 0 0 2 2 2 2 Hr1 repeat Kinase-like PF14531.6 KFR00367.1 - 4.6e-07 29.4 0.0 3.4e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFR00367.1 - 7.4e-05 21.9 0.1 0.00049 19.2 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Uds1 PF15456.6 KFR00367.1 - 0.00029 21.0 7.3 0.013 15.7 2.0 2.5 1 1 1 2 2 2 2 Up-regulated During Septation C2 PF00168.30 KFR00367.1 - 0.0095 16.2 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain PL48 PF15903.5 KFR00367.1 - 0.21 10.5 2.0 2.2 7.2 0.2 2.3 2 0 0 2 2 2 0 Filopodia upregulated, FAM65 Fib_alpha PF08702.10 KFR00367.1 - 1.9 8.7 7.7 0.32 11.2 2.7 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TFIIB PF00382.19 KFR00368.1 - 7e-53 176.6 2.1 1.1e-25 89.4 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KFR00368.1 - 2e-14 52.8 0.3 3.2e-14 52.2 0.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 KFR00368.1 - 2.8e-09 36.8 0.0 7.3e-07 29.0 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFR00368.1 - 0.0016 18.5 0.4 0.07 13.2 0.0 2.4 1 1 1 2 2 2 1 Cyclin, C-terminal domain RB_B PF01857.20 KFR00368.1 - 0.0028 17.7 0.1 0.0079 16.2 0.1 1.7 1 1 0 2 2 2 1 Retinoblastoma-associated protein B domain Sigma70_r4 PF04545.16 KFR00368.1 - 0.014 14.9 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 Aminotran_1_2 PF00155.21 KFR00369.1 - 1.2e-51 176.0 0.0 1.4e-51 175.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KFR00369.1 - 0.00024 19.8 0.0 0.00043 18.9 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KFR00369.1 - 0.003 16.9 0.0 0.0053 16.1 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SLC35F PF06027.12 KFR00369.1 - 0.07 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Solute carrier family 35 OKR_DC_1 PF01276.20 KFR00369.1 - 0.074 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Pannexin_like PF12534.8 KFR00370.1 - 3.8e-126 420.9 15.4 5e-126 420.5 15.4 1.2 1 0 0 1 1 1 1 Pannexin-like TM region of LRRC8 LRR_8 PF13855.6 KFR00370.1 - 6.4e-26 89.9 55.1 5.1e-11 42.2 4.4 7.7 5 2 3 8 8 8 6 Leucine rich repeat LRR_4 PF12799.7 KFR00370.1 - 4.6e-18 65.0 66.6 5.9e-06 26.5 0.3 9.7 5 2 6 11 11 11 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFR00370.1 - 2.2e-08 34.1 9.8 0.00023 21.1 2.8 3.9 1 1 3 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFR00370.1 - 3e-07 30.1 21.0 0.0022 17.5 1.8 3.8 1 1 2 3 3 3 3 Leucine-rich repeat Pannexin_like PF12534.8 KFR00371.1 - 9.8e-150 498.5 4.4 1.3e-149 498.0 4.4 1.2 1 0 0 1 1 1 1 Pannexin-like TM region of LRRC8 LRR_8 PF13855.6 KFR00371.1 - 3.8e-29 100.2 33.7 4.8e-10 39.1 1.1 7.7 3 2 4 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 KFR00371.1 - 3.2e-20 71.9 40.6 0.00027 21.3 0.2 9.7 6 3 3 10 10 10 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFR00371.1 - 5e-09 36.2 10.1 4.1e-05 23.5 0.5 4.3 2 1 2 4 4 4 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFR00371.1 - 0.00012 21.7 13.5 0.19 11.3 0.3 4.2 2 1 2 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.6 KFR00371.1 - 0.027 14.5 23.2 0.78 9.9 0.1 8.5 9 0 0 9 9 9 0 Leucine Rich repeat LRR_1 PF00560.33 KFR00371.1 - 0.22 12.2 34.8 6 7.8 0.0 11.1 11 0 0 11 11 11 0 Leucine Rich Repeat DUSP PF06337.12 KFR00371.1 - 0.53 10.9 2.2 1.4 9.6 0.0 2.7 3 0 0 3 3 3 0 DUSP domain Pannexin_like PF12534.8 KFR00372.1 - 1.4e-157 524.3 7.3 2.1e-157 523.7 7.3 1.3 1 0 0 1 1 1 1 Pannexin-like TM region of LRRC8 LRR_8 PF13855.6 KFR00372.1 - 1.1e-33 114.7 40.0 7.7e-10 38.4 1.7 7.1 2 2 7 9 9 9 7 Leucine rich repeat LRR_4 PF12799.7 KFR00372.1 - 4.7e-24 84.0 43.4 5.9e-06 26.5 1.3 8.9 4 2 7 11 11 11 10 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFR00372.1 - 1.1e-10 41.3 15.9 5.3e-06 26.0 1.8 3.6 1 1 1 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 KFR00372.1 - 4.7e-06 26.4 37.9 1.4 9.7 0.1 10.7 10 2 0 10 10 10 4 Leucine Rich Repeat AKAP95 PF04988.12 KFR00373.1 - 2.8e-67 226.0 14.1 5.2e-67 225.2 14.1 1.4 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.7 KFR00373.1 - 0.035 14.4 9.9 0.8 10.1 1.4 2.4 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF678 PF05077.12 KFR00373.1 - 0.069 13.3 0.4 4.3 7.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF678) zf-Di19 PF05605.12 KFR00373.1 - 0.16 12.3 8.0 0.78 10.1 0.6 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Eapp_C PF10238.9 KFR00373.1 - 1.8 8.6 10.6 0.78 9.8 3.0 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein zf-C2H2_4 PF13894.6 KFR00375.1 - 8.5e-18 63.5 47.9 0.00092 19.9 0.3 9.0 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2 PF00096.26 KFR00375.1 - 1.7e-05 25.0 56.9 0.00033 20.9 0.5 9.0 8 1 0 8 8 8 4 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 KFR00375.1 - 0.00095 18.8 14.5 0.15 11.7 0.5 5.0 5 0 0 5 5 5 3 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_7 PF15269.6 KFR00375.1 - 0.027 14.6 24.8 0.063 13.4 0.9 5.3 4 1 1 5 5 5 0 Zinc-finger zf-C2H2_jaz PF12171.8 KFR00375.1 - 0.064 13.6 19.4 0.92 9.9 0.0 6.1 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding Metallothio_Pro PF02069.16 KFR00375.1 - 0.36 11.1 5.0 1.7 9.0 5.0 2.2 1 0 0 1 1 1 0 Prokaryotic metallothionein zf-C2H2_8 PF15909.5 KFR00375.1 - 1.5 9.2 21.4 0.67 10.3 4.1 4.4 2 1 1 3 3 3 0 C2H2-type zinc ribbon Glutaredoxin PF00462.24 KFR00375.1 - 2.2 8.6 5.2 19 5.5 0.3 3.7 4 0 0 4 4 4 0 Glutaredoxin FYVE PF01363.21 KFR00375.1 - 2.7 8.2 18.5 1.2 9.4 6.1 5.4 5 1 0 5 5 5 0 FYVE zinc finger zf-C2H2_2 PF12756.7 KFR00375.1 - 2.7 8.4 27.6 5 7.5 0.0 6.3 4 1 2 6 6 6 0 C2H2 type zinc-finger (2 copies) Sec63 PF02889.16 KFR00376.1 - 1.4e-49 168.6 3.1 3.1e-49 167.5 3.1 1.6 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KFR00376.1 - 1.1e-24 87.1 0.0 5.2e-24 85.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KFR00376.1 - 4.6e-13 49.5 0.0 1.6e-12 47.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFR00376.1 - 6.8e-11 42.5 0.0 5.5e-10 39.6 0.0 2.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFR00376.1 - 0.00099 19.4 0.0 0.003 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Pkinase PF00069.25 KFR00377.1 - 9.7e-48 162.8 0.0 7.4e-26 91.1 0.1 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KFR00377.1 - 6.4e-17 61.7 0.0 3.1e-13 49.6 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KFR00377.1 - 0.018 15.0 0.0 0.28 11.1 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KFR00377.1 - 0.17 11.2 0.4 16 4.7 0.0 2.8 3 0 0 3 3 3 0 Kinase-like MMR1 PF08505.10 KFR00377.1 - 1.9 8.7 8.7 0.15 12.3 3.8 1.6 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Zona_pellucida PF00100.23 KFR00378.1 - 1.2e-40 139.9 0.3 2.5e-40 138.9 0.3 1.5 1 0 0 1 1 1 1 Zona pellucida-like domain Bromodomain PF00439.25 KFR00380.1 - 2.4e-29 101.2 3.9 8.5e-19 67.4 0.5 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KFR00380.1 - 1.7e-27 95.4 0.2 1.7e-27 95.4 0.2 3.2 3 1 0 3 3 3 1 Bromodomain extra-terminal - transcription regulation BRD4_CDT PF17105.5 KFR00380.1 - 1.9e-22 78.6 3.9 1.9e-22 78.6 3.9 2.4 2 0 0 2 2 2 1 C-terminal domain of bromodomain protein 4 Abhydrolase_1 PF00561.20 KFR00381.1 - 3.6e-24 85.8 0.0 6.6e-22 78.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFR00381.1 - 1.6e-19 71.4 0.0 2.1e-19 71.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFR00381.1 - 5.8e-11 42.1 0.0 3e-08 33.2 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ndr PF03096.14 KFR00381.1 - 7.3e-05 21.6 0.0 0.0044 15.8 0.0 2.1 2 0 0 2 2 2 2 Ndr family PGAP1 PF07819.13 KFR00381.1 - 0.0091 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 KFR00381.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) BTB PF00651.31 KFR00382.1 - 1.7e-21 76.5 0.0 1.2e-20 73.8 0.0 2.0 1 1 1 2 2 2 1 BTB/POZ domain SPOB_ab PF14682.6 KFR00382.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal DUF4596 PF15363.6 KFR00383.1 - 4.4e-28 97.3 8.3 1.3e-27 95.7 5.9 3.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4596) BACK PF07707.15 KFR00383.1 - 0.12 12.5 0.3 3.1 7.9 0.1 2.5 2 0 0 2 2 2 0 BTB And C-terminal Kelch DUF4580 PF15162.6 KFR00384.1 - 1.9e-77 258.4 1.3 2e-77 258.3 1.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4580) Kinetochor_Ybp2 PF08568.10 KFR00385.1 - 4.7e-92 309.5 19.1 5.7e-92 309.2 19.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin zf-AD PF07776.15 KFR00385.1 - 0.0029 17.8 1.5 0.0045 17.2 0.1 2.1 2 0 0 2 2 2 1 Zinc-finger associated domain (zf-AD) Colipase-like PF15083.6 KFR00385.1 - 1.8 8.8 8.9 0.056 13.6 1.2 2.5 3 0 0 3 3 3 0 Colipase-like RPAP2_Rtr1 PF04181.13 KFR00386.1 - 1.5e-24 86.1 4.7 3.3e-24 85.0 3.2 2.4 2 0 0 2 2 2 1 Rtr1/RPAP2 family Peptidase_M27 PF01742.17 KFR00386.1 - 0.006 15.8 0.1 0.011 14.9 0.1 1.4 1 0 0 1 1 1 1 Clostridial neurotoxin zinc protease zf-C2H2 PF00096.26 KFR00387.1 - 4.3e-29 99.3 48.2 8.2e-06 26.0 1.0 6.8 7 0 0 7 7 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFR00387.1 - 3.3e-27 93.6 41.9 1.4e-06 28.5 2.0 7.2 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR00387.1 - 1e-22 78.8 41.6 0.00074 20.1 0.8 6.6 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFR00387.1 - 3.7e-15 55.5 39.1 0.0026 17.7 2.8 6.5 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFR00387.1 - 4.3e-15 55.5 15.4 0.0081 16.4 0.0 6.4 6 0 0 6 6 6 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFR00387.1 - 2.7e-07 30.8 26.1 0.011 16.1 0.3 5.8 6 0 0 6 6 6 3 Zinc-finger of C2H2 type Ta0938 PF11494.8 KFR00387.1 - 7e-05 23.1 1.6 0.031 14.6 0.0 2.8 2 1 1 3 3 3 1 Ta0938 zf-BED PF02892.15 KFR00387.1 - 0.00089 19.2 29.3 0.02 14.9 0.9 5.7 4 1 1 6 6 6 2 BED zinc finger zf_UBZ PF18439.1 KFR00387.1 - 0.0017 17.9 17.3 6.7 6.4 0.1 6.1 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 KFR00387.1 - 0.0021 18.3 21.6 0.15 12.4 3.6 4.4 3 1 1 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-CHCC PF10276.9 KFR00387.1 - 0.0085 16.1 10.2 0.47 10.6 0.3 4.5 4 0 0 4 4 4 2 Zinc-finger domain zf-C2H2_3rep PF18868.1 KFR00387.1 - 0.0095 16.6 20.2 0.68 10.6 2.1 5.0 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf_C2H2_ZHX PF18387.1 KFR00387.1 - 0.026 14.2 1.5 0.026 14.2 1.5 3.5 3 2 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain Prok-RING_1 PF14446.6 KFR00387.1 - 0.054 13.4 15.9 9.2 6.3 0.1 5.9 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 FYVE PF01363.21 KFR00387.1 - 0.055 13.6 25.8 1.6 8.9 9.3 4.0 1 1 3 4 4 4 0 FYVE zinc finger zinc_ribbon_15 PF17032.5 KFR00387.1 - 0.055 14.2 12.4 3.6 8.4 1.1 3.8 2 1 2 4 4 3 0 zinc-ribbon family GAGA PF09237.11 KFR00387.1 - 0.085 12.7 6.8 6.6 6.6 0.0 4.2 2 2 2 4 4 4 0 GAGA factor HypA PF01155.19 KFR00387.1 - 0.16 12.0 11.3 1 9.4 0.5 3.4 1 1 3 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 KFR00387.1 - 0.17 12.1 26.2 1.2 9.3 2.9 5.7 4 2 2 6 6 6 0 Zinc ribbon domain BolA PF01722.18 KFR00387.1 - 0.18 12.1 7.5 0.98 9.7 0.5 3.4 2 2 0 2 2 2 0 BolA-like protein HNH_5 PF14279.6 KFR00387.1 - 0.19 11.6 17.7 3.7 7.5 0.8 5.8 6 1 0 6 6 5 0 HNH endonuclease zf-C2H2_11 PF16622.5 KFR00387.1 - 0.2 11.4 29.8 4.9 7.0 0.2 6.3 6 0 0 6 6 6 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFR00387.1 - 0.27 11.2 25.5 1.8 8.6 1.0 5.9 6 0 0 6 6 6 0 zinc-finger of a C2HC-type PyrI_C PF02748.15 KFR00387.1 - 0.64 10.0 13.9 1.6 8.7 0.1 5.1 5 1 1 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf_ZIC PF18366.1 KFR00387.1 - 0.65 10.1 18.1 2.5 8.3 0.1 5.1 3 1 3 6 6 6 0 Zic proteins zinc finger domain XPA_N PF01286.18 KFR00387.1 - 1.6 8.8 23.6 8 6.6 0.1 6.7 7 0 0 7 7 7 0 XPA protein N-terminal Ribosomal_S27e PF01667.17 KFR00387.1 - 2.1 8.1 10.4 1.4 8.7 0.1 4.5 4 1 1 5 5 5 0 Ribosomal protein S27 zf-C2H2_2 PF12756.7 KFR00387.1 - 2.2 8.7 23.5 8.1 6.9 0.2 5.6 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) Zf_RING PF16744.5 KFR00387.1 - 3 8.0 17.9 14 5.9 0.6 5.4 1 1 5 6 6 6 0 KIAA1045 RING finger zf-AN1 PF01428.16 KFR00387.1 - 4.1 7.7 34.0 5.3 7.3 0.7 6.9 5 2 2 7 7 7 0 AN1-like Zinc finger Arc_trans_TRASH PF08394.10 KFR00387.1 - 5.9 7.3 9.2 57 4.2 0.1 4.7 3 2 0 3 3 3 0 Archaeal TRASH domain ADK_lid PF05191.14 KFR00387.1 - 6.8 6.8 15.3 22 5.2 4.6 4.6 3 2 1 4 4 4 0 Adenylate kinase, active site lid RabGAP-TBC PF00566.18 KFR00388.1 - 5.8e-54 183.0 2.7 5.8e-54 183.0 2.7 2.2 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DUF1129 PF06570.11 KFR00388.1 - 0.087 12.3 0.2 0.087 12.3 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) PARP_reg PF02877.14 KFR00388.1 - 0.12 12.5 7.8 0.14 12.2 0.7 2.9 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain DUF1707 PF08044.11 KFR00388.1 - 0.55 10.3 2.8 0.99 9.5 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) Surfac_D-trimer PF09006.11 KFR00388.1 - 0.95 9.4 7.2 10 6.1 0.2 4.1 4 0 0 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation Ribosomal_L5e PF17144.4 KFR00389.1 - 9.8e-95 315.1 1.0 2e-94 314.1 1.0 1.5 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KFR00389.1 - 1.1e-39 135.3 9.7 1.1e-39 135.3 9.7 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF1476 PF07345.11 KFR00389.1 - 0.0099 16.2 0.2 0.023 15.0 0.2 1.7 1 0 0 1 1 1 1 ATPase inhibitor subunit zeta PIP49_C PF12260.8 KFR00390.1 - 6.3e-66 221.6 0.1 1.1e-65 220.8 0.1 1.4 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 PIP49_N PF14875.6 KFR00390.1 - 4.4e-58 195.6 0.3 4.4e-58 195.6 0.3 2.2 2 0 0 2 2 2 1 N-term cysteine-rich ER, FAM69 EMP24_GP25L PF01105.24 KFR00391.1 - 2.6e-48 164.4 0.2 3e-48 164.2 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3786 PF12654.7 KFR00392.1 - 0.32 10.6 5.3 0.29 10.7 1.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3786) Raco_middle PF17651.1 KFR00392.1 - 0.58 9.8 4.9 3.4 7.3 1.3 3.0 2 0 0 2 2 2 0 RACo middle region adh_short PF00106.25 KFR00393.1 - 5.7e-39 133.6 0.0 8.3e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFR00393.1 - 4.1e-25 88.7 0.0 5.4e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFR00393.1 - 6e-09 36.1 0.0 8.6e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KFR00393.1 - 0.00027 20.5 0.0 0.00039 19.9 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Eno-Rase_NADH_b PF12242.8 KFR00393.1 - 0.00051 19.7 0.0 0.0073 16.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FCH PF00611.23 KFR00394.1 - 3.3e-20 72.1 0.8 2.5e-19 69.3 0.0 2.8 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KFR00394.1 - 1.3e-12 47.1 0.1 2.8e-12 46.0 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFR00394.1 - 2.9e-11 43.1 0.0 6.6e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFR00394.1 - 1.1e-06 28.2 0.1 2.3e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFR00394.1 - 8.3e-05 22.8 0.1 0.00016 21.9 0.1 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain Lzipper-MIP1 PF14389.6 KFR00394.1 - 0.0018 18.5 0.9 0.0053 17.0 0.9 1.8 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 HR1 PF02185.16 KFR00394.1 - 0.0058 16.7 0.4 0.0058 16.7 0.4 3.4 3 0 0 3 3 3 1 Hr1 repeat COG5 PF10392.9 KFR00394.1 - 0.068 13.3 0.2 0.068 13.3 0.2 2.4 2 1 1 3 3 3 0 Golgi transport complex subunit 5 DUF4140 PF13600.6 KFR00394.1 - 0.084 13.3 6.8 0.59 10.6 0.2 3.0 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DEDD_Tnp_IS110 PF01548.17 KFR00394.1 - 0.33 10.8 5.7 0.062 13.2 0.9 2.2 2 0 0 2 2 2 0 Transposase Exonuc_VII_L PF02601.15 KFR00394.1 - 0.67 9.5 12.0 0.33 10.5 5.5 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Uds1 PF15456.6 KFR00394.1 - 6.2 7.0 15.7 0.13 12.4 1.3 3.0 2 1 0 2 2 2 0 Up-regulated During Septation SH2 PF00017.24 KFR00395.1 - 1.3e-14 54.0 0.2 3.7e-14 52.6 0.0 1.9 2 0 0 2 2 2 1 SH2 domain RasGEF PF00617.19 KFR00395.1 - 3.6e-12 46.8 0.0 7.9e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain Fcf2 PF08698.11 KFR00396.1 - 1.3e-38 131.3 11.0 3.9e-38 129.7 0.5 4.2 4 1 0 4 4 4 2 Fcf2 pre-rRNA processing Aldo_ket_red PF00248.21 KFR00397.1 - 1.6e-06 27.6 0.0 2.4e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Steroid_dh PF02544.16 KFR00398.1 - 3.9e-26 91.8 5.7 7.3e-26 91.0 5.7 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase RhoGAP PF00620.27 KFR00399.1 - 4.9e-50 169.3 0.4 4.9e-50 169.3 0.4 2.2 2 0 0 2 2 2 1 RhoGAP domain C1_1 PF00130.22 KFR00399.1 - 1.2e-06 28.3 9.9 2.9e-06 27.1 9.9 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PIN_5 PF08745.11 KFR00399.1 - 0.031 13.7 3.5 2.4 7.5 0.3 3.3 3 0 0 3 3 3 0 PINc domain ribonuclease Exonuc_VII_L PF02601.15 KFR00399.1 - 2.9 7.4 10.5 6.6 6.2 10.5 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit ABC_membrane_2 PF06472.15 KFR00400.1 - 3.6e-97 325.0 7.3 4.8e-97 324.6 7.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KFR00400.1 - 5.8e-18 65.7 0.0 1.3e-17 64.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 KFR00400.1 - 0.00058 20.4 0.0 0.0017 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 KFR00400.1 - 0.0017 17.9 0.0 0.27 10.6 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFR00400.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFR00400.1 - 0.019 14.7 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 KFR00400.1 - 0.03 14.2 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_27 PF13514.6 KFR00400.1 - 0.037 13.6 0.0 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KFR00400.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KFR00400.1 - 0.13 12.8 0.0 0.33 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KFR00400.1 - 0.15 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Interfer-bind PF09294.10 KFR00401.1 - 7.3e-19 68.0 0.5 2.5e-18 66.3 0.1 1.8 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.17 KFR00401.1 - 1e-16 60.7 0.6 2.1e-16 59.7 0.6 1.5 1 0 0 1 1 1 1 Tissue factor Orf78 PF06024.12 KFR00401.1 - 0.0045 17.3 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 Orf78 (ac78) DUF4064 PF13273.6 KFR00401.1 - 0.015 15.6 0.1 0.026 14.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) TMEM154 PF15102.6 KFR00401.1 - 0.051 13.5 0.7 0.051 13.5 0.7 1.8 2 0 0 2 2 2 0 TMEM154 protein family Sarcoglycan_2 PF05510.13 KFR00401.1 - 0.12 11.1 0.1 0.22 10.3 0.0 1.5 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon EphA2_TM PF14575.6 KFR00401.1 - 0.18 12.7 1.1 0.55 11.2 1.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Choline_transpo PF04515.12 KFR00402.1 - 5.1e-93 311.8 36.5 5.1e-93 311.8 36.5 2.6 2 1 1 3 3 3 1 Plasma-membrane choline transporter DUF3671 PF12420.8 KFR00402.1 - 0.45 10.6 5.2 0.17 12.0 1.1 2.4 1 1 1 2 2 2 0 Protein of unknown function Calponin PF00402.18 KFR00403.1 - 1.9e-44 148.9 16.5 4.8e-16 58.1 1.5 3.5 3 0 0 3 3 3 3 Calponin family repeat CH PF00307.31 KFR00403.1 - 8.8e-23 80.6 0.1 1.3e-22 80.0 0.1 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Raf1_HTH PF18579.1 KFR00403.1 - 0.14 11.8 0.0 0.52 10.0 0.0 2.0 2 0 0 2 2 2 0 Rubisco accumulation factor 1 helix turn helix domain CAMSAP_CH PF11971.8 KFR00403.1 - 0.18 11.7 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain Alg14 PF08660.11 KFR00404.1 - 1.3e-63 214.0 0.0 1.5e-63 213.9 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like TRAM_LAG1_CLN8 PF03798.16 KFR00405.1 - 2.7e-36 125.2 15.7 2.7e-36 125.2 15.7 1.5 2 0 0 2 2 2 1 TLC domain DUF2254 PF10011.9 KFR00405.1 - 7.5 5.3 7.2 0.5 9.1 1.5 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) Cyto_heme_lyase PF01265.17 KFR00406.1 - 5.5e-72 242.8 20.2 8.9e-71 238.8 20.2 2.5 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase RWD PF05773.22 KFR00407.1 - 2.5e-18 66.4 0.3 4.9e-18 65.5 0.3 1.5 1 0 0 1 1 1 1 RWD domain DUF1115 PF06544.12 KFR00407.1 - 8.3e-06 26.0 1.3 0.001 19.2 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1115) RRM_5 PF13893.6 KFR00408.1 - 1.1e-53 180.1 1.6 2.2e-39 133.9 0.0 4.1 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KFR00408.1 - 1.3e-32 111.4 0.3 1.9e-08 34.0 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KFR00408.1 - 2e-16 60.0 0.0 2.9e-15 56.2 0.0 2.3 2 0 0 2 2 2 1 RRM-like domain RRM_occluded PF16842.5 KFR00408.1 - 3.3e-10 39.7 0.2 0.018 14.9 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif DHO_dh PF01180.21 KFR00409.1 - 6.1e-34 117.6 0.0 1.1e-33 116.7 0.0 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Fer4_20 PF14691.6 KFR00409.1 - 1.8e-28 98.5 0.9 1.8e-28 98.5 0.9 2.4 3 0 0 3 3 3 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_21 PF14697.6 KFR00409.1 - 4.8e-24 84.3 12.2 4.8e-24 84.3 12.2 3.5 3 1 0 3 3 3 1 4Fe-4S dicluster domain Pyr_redox_2 PF07992.14 KFR00409.1 - 2.8e-13 49.8 0.0 1.5e-12 47.4 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFR00409.1 - 3e-08 33.8 0.0 7.8e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KFR00409.1 - 6.5e-07 28.9 0.0 0.004 16.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Dus PF01207.17 KFR00409.1 - 1.4e-06 27.7 0.0 1e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Fer4_7 PF12838.7 KFR00409.1 - 2.6e-05 24.7 10.3 2.6e-05 24.7 10.3 3.4 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KFR00409.1 - 4.9e-05 23.4 25.9 0.00021 21.3 10.9 3.0 2 2 1 3 3 3 3 4Fe-4S dicluster domain Pyr_redox PF00070.27 KFR00409.1 - 0.00012 22.5 0.1 0.8 10.3 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_6 PF12837.7 KFR00409.1 - 0.00034 20.6 1.8 0.00034 20.6 1.8 4.4 4 1 1 5 5 5 2 4Fe-4S binding domain Fer4_9 PF13187.6 KFR00409.1 - 0.0014 18.7 25.2 0.0032 17.6 12.3 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 KFR00409.1 - 0.0015 18.5 13.5 0.0028 17.6 2.3 4.6 5 0 0 5 5 4 2 4Fe-4S binding domain Fer4 PF00037.27 KFR00409.1 - 0.0039 17.0 30.4 0.0065 16.2 4.6 4.9 5 0 0 5 5 5 2 4Fe-4S binding domain Thi4 PF01946.17 KFR00409.1 - 0.031 13.5 0.0 0.071 12.3 0.0 1.6 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 KFR00409.1 - 0.15 11.6 0.0 0.4 10.2 0.0 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KFR00409.1 - 0.2 11.7 0.0 28 4.8 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase MCRA PF06100.11 KFR00409.1 - 0.25 10.1 0.0 0.52 9.0 0.0 1.4 1 0 0 1 1 1 0 MCRA family RT_RNaseH_2 PF17919.1 KFR00410.1 - 0.0015 18.5 0.0 0.0042 17.1 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFR00410.1 - 0.047 13.2 0.0 0.08 12.4 0.0 1.5 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PX PF00787.24 KFR00412.1 - 3.3e-26 91.5 0.8 6.7e-26 90.5 0.8 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KFR00412.1 - 2.9e-05 23.8 6.0 0.0011 18.5 2.2 2.5 2 1 0 2 2 2 1 Vps5 C terminal like BAR_3_WASP_bdg PF10456.9 KFR00412.1 - 0.066 12.7 0.8 0.25 10.8 0.1 2.0 2 1 0 3 3 3 0 WASP-binding domain of Sorting nexin protein BAR PF03114.18 KFR00412.1 - 0.067 12.8 3.2 0.28 10.8 3.2 1.9 1 1 0 1 1 1 0 BAR domain NuA4 PF09340.10 KFR00412.1 - 0.14 12.0 0.2 0.14 12.0 0.2 2.3 2 1 1 3 3 3 0 Histone acetyltransferase subunit NuA4 Muted PF14942.6 KFR00412.1 - 0.37 11.1 4.5 9.7 6.5 0.1 2.8 2 1 1 4 4 4 0 Organelle biogenesis, Muted-like protein PAP2 PF01569.21 KFR00413.1 - 5.2e-22 78.1 2.9 6.9e-22 77.7 2.9 1.2 1 0 0 1 1 1 1 PAP2 superfamily Tim17 PF02466.19 KFR00413.1 - 0.094 13.1 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family MtrF PF09472.10 KFR00413.1 - 0.19 11.1 0.8 0.41 10.1 0.8 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) PAP2 PF01569.21 KFR00414.1 - 3.1e-17 62.6 1.6 4.8e-17 62.0 1.6 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KFR00414.1 - 0.11 12.2 0.3 0.18 11.5 0.3 1.4 1 0 0 1 1 1 0 PAP2 superfamily Paralemmin PF03285.15 KFR00415.1 - 5.6e-55 187.1 18.5 1.2e-53 182.8 18.5 2.3 1 1 0 1 1 1 1 Paralemmin Mu-like_Pro PF10123.9 KFR00415.1 - 0.011 15.3 8.1 0.023 14.3 8.1 1.4 1 0 0 1 1 1 0 Mu-like prophage I protein Syntaxin-6_N PF09177.11 KFR00415.1 - 0.69 10.5 9.5 2.7 8.6 9.5 2.1 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Nup54 PF13874.6 KFR00415.1 - 1.7 8.7 16.0 1.2 9.3 13.3 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 FlaC_arch PF05377.11 KFR00415.1 - 2.1 8.8 6.0 3 8.3 3.2 2.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.19 KFR00415.1 - 5.2 4.9 9.0 11 3.8 9.0 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ERM PF00769.19 KFR00415.1 - 8.9 6.0 30.8 0.0083 16.0 18.2 2.2 3 0 0 3 3 3 0 Ezrin/radixin/moesin family Reeler PF02014.16 KFR00416.1 - 1.4e-30 106.7 0.0 2.2e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 Reeler domain DOMON PF03351.17 KFR00416.1 - 1.1e-17 64.4 0.0 2e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 KFR00416.1 - 2.1e-05 24.7 9.6 2.1e-05 24.7 9.6 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Claudin_3 PF06653.11 KFR00416.1 - 0.067 13.1 6.7 0.37 10.7 6.2 2.1 1 1 1 2 2 2 0 Tight junction protein, Claudin-like DUF4079 PF13301.6 KFR00416.1 - 8.2 6.6 10.5 38 4.4 10.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) hDGE_amylase PF14701.6 KFR00417.1 - 3.9e-165 550.2 0.2 5.1e-165 549.8 0.2 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KFR00417.1 - 2.3e-136 454.7 0.0 3.6e-136 454.1 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KFR00417.1 - 1.1e-77 261.1 0.0 1.8e-77 260.5 0.0 1.3 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KFR00417.1 - 1.1e-20 73.5 0.0 2.1e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 KFR00417.1 - 4.8e-05 23.1 0.3 0.00038 20.1 0.0 2.3 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Nuc_sug_transp PF04142.15 KFR00418.1 - 1.4e-138 461.4 18.5 1.6e-138 461.2 18.5 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KFR00418.1 - 2.5e-07 31.0 28.7 1.7e-05 25.0 1.6 2.6 3 0 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 KFR00418.1 - 3.2e-06 26.6 9.6 3.2e-06 26.6 9.6 2.2 1 1 1 2 2 2 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 KFR00418.1 - 1.9e-05 23.8 2.9 1.9e-05 23.8 2.9 1.7 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EmrE PF13536.6 KFR00418.1 - 5.4e-05 22.9 8.7 8.7e-05 22.2 1.3 2.3 2 0 0 2 2 2 2 Putative multidrug resistance efflux transporter UAA PF08449.11 KFR00418.1 - 0.00034 19.9 15.4 0.00047 19.4 14.5 1.6 1 1 0 1 1 1 1 UAA transporter family DUF202 PF02656.15 KFR00418.1 - 0.037 14.5 1.1 0.037 14.5 1.1 3.8 4 1 0 4 4 4 0 Domain of unknown function (DUF202) MFS_1 PF07690.16 KFR00419.1 - 7.5e-34 117.2 37.8 1.9e-32 112.5 37.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KFR00419.1 - 1.3e-11 44.0 21.9 1.2e-09 37.5 21.9 2.9 1 1 0 1 1 1 1 MFS_1 like family CCB1 PF12046.8 KFR00419.1 - 1.8 7.9 4.4 1.4 8.2 1.3 2.3 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B SAS-6_N PF16531.5 KFR00420.1 - 1.3e-28 99.4 2.0 1.3e-28 99.4 2.0 2.5 2 0 0 2 2 2 1 Centriolar protein SAS N-terminal Sas6_CC PF18594.1 KFR00420.1 - 5.8e-14 51.6 7.3 5.8e-14 51.6 7.3 4.2 5 0 0 5 5 5 1 Sas6/XLF/XRCC4 coiled-coil domain Tropomyosin_1 PF12718.7 KFR00420.1 - 0.012 15.8 14.9 0.012 15.8 14.9 5.0 1 1 4 5 5 5 0 Tropomyosin like Spc7 PF08317.11 KFR00420.1 - 0.034 13.0 81.1 0.49 9.2 27.7 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein PI3K_P85_iSH2 PF16454.5 KFR00420.1 - 7.3 6.2 67.7 0.58 9.7 24.6 4.1 1 1 2 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TRM13 PF05206.14 KFR00421.1 - 1.9e-90 303.0 1.6 3.3e-90 302.2 1.6 1.4 1 1 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 KFR00421.1 - 3e-13 49.3 3.5 3e-13 49.3 3.5 2.4 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.12 KFR00421.1 - 3.2e-11 42.9 1.9 6.7e-11 41.9 1.9 1.6 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger LRR_8 PF13855.6 KFR00422.1 - 8.8e-31 105.5 25.5 1.9e-09 37.1 1.7 3.7 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFR00422.1 - 1.7e-24 85.4 19.8 7.7e-06 26.2 1.1 5.4 2 1 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFR00422.1 - 1.8e-06 27.7 18.5 4.6 8.2 0.0 8.5 8 0 0 8 8 8 1 Leucine Rich Repeat SPATA19 PF15212.6 KFR00422.1 - 0.082 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Spermatogenesis-associated protein 19, mitochondrial LRR_6 PF13516.6 KFR00422.1 - 3.8 7.8 19.6 26 5.2 0.2 6.8 7 0 0 7 7 7 0 Leucine Rich repeat 2-oxoacid_dh PF00198.23 KFR00423.1 - 1.2e-79 267.1 0.0 1.8e-79 266.5 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFR00423.1 - 1e-18 66.9 0.1 1.9e-18 66.1 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KFR00423.1 - 3.7e-15 56.0 0.0 8.4e-15 54.8 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain Toprim_Crpt PF13342.6 KFR00423.1 - 0.12 12.3 0.1 0.99 9.4 0.0 2.2 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase RTC PF01137.21 KFR00424.1 - 3.6e-84 281.4 0.2 4e-84 281.2 0.2 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KFR00424.1 - 6.3e-24 84.5 0.1 1.1e-23 83.7 0.1 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Ig_3 PF13927.6 KFR00425.1 - 2.4e-49 165.8 8.8 1.1e-14 54.7 0.1 5.3 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 KFR00425.1 - 1.6e-45 153.1 2.6 9.3e-17 60.9 0.2 5.0 4 1 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.6 KFR00425.1 - 1e-39 134.7 7.4 2.2e-10 40.7 0.0 5.2 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 KFR00425.1 - 3.9e-32 110.3 5.3 8.6e-10 38.7 0.1 5.5 5 0 0 5 5 5 4 Immunoglobulin domain V-set PF07686.17 KFR00425.1 - 7e-21 74.4 12.8 2.4e-05 24.4 0.0 9.0 5 4 4 9 9 9 3 Immunoglobulin V-set domain C2-set PF05790.15 KFR00425.1 - 6.6e-13 48.7 6.8 9.4e-12 45.0 0.3 3.5 4 0 0 4 4 3 1 Immunoglobulin C2-set domain C2-set_2 PF08205.12 KFR00425.1 - 4.7e-11 42.6 5.2 0.15 12.1 0.0 6.0 6 1 0 6 6 6 3 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFR00425.1 - 1.2e-10 41.6 1.6 0.0029 18.0 0.1 4.8 5 0 0 5 5 5 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain ICAM_N PF03921.14 KFR00425.1 - 1.9e-07 30.6 2.4 0.017 14.8 0.1 3.6 3 0 0 3 3 3 2 Intercellular adhesion molecule (ICAM), N-terminal domain DUF2808 PF10989.8 KFR00425.1 - 1.6e-06 28.2 1.9 0.037 14.0 0.2 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF2808) Ig_6 PF18452.1 KFR00425.1 - 2.8e-06 26.8 0.1 0.23 11.1 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain Ig_4 PF16680.5 KFR00425.1 - 3.4e-06 27.2 3.7 0.0019 18.4 0.1 4.4 4 1 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Receptor_2B4 PF11465.8 KFR00425.1 - 6e-06 26.4 0.2 0.26 11.5 0.0 4.0 3 1 0 3 3 3 1 Natural killer cell receptor 2B4 Herpes_gE PF02480.16 KFR00425.1 - 2.7e-05 23.1 2.6 0.0011 17.9 0.1 2.9 2 1 1 4 4 4 1 Alphaherpesvirus glycoprotein E Izumo-Ig PF16706.5 KFR00425.1 - 5.9e-05 23.1 0.3 0.063 13.3 0.0 4.0 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain C1-set PF07654.15 KFR00425.1 - 0.00036 20.9 5.0 0.16 12.4 0.1 5.0 6 0 0 6 6 5 1 Immunoglobulin C1-set domain Ig_C17orf99 PF17736.1 KFR00425.1 - 0.0039 17.2 1.7 0.23 11.5 0.0 3.9 3 1 1 4 4 4 1 C17orf99 Ig domain Syndecan PF01034.20 KFR00425.1 - 0.024 14.6 0.2 5.5 7.0 0.2 2.7 3 0 0 3 3 2 0 Syndecan domain MAGUK_N_PEST PF10608.9 KFR00425.1 - 1 9.8 5.7 3.9 7.9 1.6 3.0 2 1 0 2 2 2 0 Polyubiquitination (PEST) N-terminal domain of MAGUK Adeno_E3_CR1 PF02440.15 KFR00425.1 - 4.4 7.1 7.9 6.3 6.6 0.3 3.6 4 2 0 4 4 4 0 Adenovirus E3 region protein CR1 7tm_1 PF00001.21 KFR00426.1 - 1e-16 61.1 0.1 1.3e-16 60.7 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFR00426.1 - 4e-09 36.5 0.4 5.8e-09 36.0 0.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFR00426.1 - 0.0041 16.5 0.9 0.0064 15.9 0.9 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx MtrF PF09472.10 KFR00426.1 - 0.096 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DSPn PF14671.6 KFR00427.1 - 1.5e-61 206.9 2.8 4.8e-61 205.3 1.8 2.2 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KFR00427.1 - 1.5e-14 54.0 0.1 5.5e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFR00427.1 - 3e-06 27.5 0.0 5.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KFR00427.1 - 5.5e-05 22.8 0.0 8.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFR00427.1 - 0.017 15.1 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Glyco_transf_64 PF09258.10 KFR00428.1 - 2.2e-86 289.1 0.0 2.6e-86 288.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_tranf_2_3 PF13641.6 KFR00428.1 - 6.7e-05 22.9 0.0 9.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KFR00428.1 - 0.0027 17.5 0.0 0.0042 16.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cation_efflux PF01545.21 KFR00429.1 - 2e-41 142.0 6.1 2.3e-41 141.7 6.1 1.1 1 0 0 1 1 1 1 Cation efflux family ArsP_1 PF03773.13 KFR00429.1 - 0.0082 15.3 0.1 0.012 14.8 0.1 1.3 1 0 0 1 1 1 1 Predicted permease TP_methylase PF00590.20 KFR00430.1 - 2.6e-23 83.1 0.0 6.8e-23 81.7 0.0 1.6 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Aldo_ket_red PF00248.21 KFR00431.1 - 1.9e-55 188.2 0.0 1.9e-43 148.8 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Collagen PF01391.18 KFR00433.1 - 4.7e-156 506.7 682.1 5.7e-09 35.6 21.1 22.7 4 2 11 15 15 15 9 Collagen triple helix repeat (20 copies) COLFI PF01410.18 KFR00433.1 - 2.1e-98 328.3 0.1 2.9e-98 327.9 0.1 1.2 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Laminin_G_2 PF02210.24 KFR00433.1 - 4.5e-05 24.0 0.0 7.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.6 KFR00433.1 - 0.00038 20.6 0.0 0.00067 19.8 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_1 PF00054.23 KFR00433.1 - 0.0027 17.9 0.0 0.0057 16.9 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Plasmod_Pvs28 PF06247.11 KFR00507.1 - 0.2 12.0 4.0 0.58 10.5 4.0 1.7 1 0 0 1 1 1 0 Pvs28 EGF domain EGF_2 PF07974.13 KFR00507.1 - 1.4 9.4 4.6 4.9 7.6 4.6 1.9 1 0 0 1 1 1 0 EGF-like domain Y_phosphatase PF00102.27 KFR00508.1 - 9.2e-17 61.4 0.2 9.9e-17 61.3 0.2 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFR00508.1 - 2.1e-05 24.4 0.1 2.7e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain L6_membrane PF05805.12 KFR00529.1 - 2.4e-74 249.1 18.2 2.7e-74 248.9 18.2 1.0 1 0 0 1 1 1 1 L6 membrane protein L6_membrane PF05805.12 KFR00530.1 - 2.1e-68 229.7 14.7 2.4e-68 229.5 14.7 1.0 1 0 0 1 1 1 1 L6 membrane protein Yip1 PF04893.17 KFR00530.1 - 0.0018 18.0 0.1 0.0018 18.0 0.1 2.2 2 1 0 2 2 2 1 Yip1 domain L6_membrane PF05805.12 KFR00531.1 - 1.5e-52 177.9 17.1 1.7e-52 177.8 17.1 1.0 1 0 0 1 1 1 1 L6 membrane protein Cu-oxidase_3 PF07732.15 KFR00532.1 - 6e-30 103.7 3.9 1.9e-09 37.6 0.0 5.2 4 0 0 4 4 4 4 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFR00532.1 - 1.2e-26 93.1 18.6 6.4e-15 55.1 6.5 6.4 6 2 0 6 6 6 4 Multicopper oxidase PKD PF00801.20 KFR00532.1 - 0.069 13.0 1.4 14 5.6 0.1 4.2 5 0 0 5 5 5 0 PKD domain VitD-bind_III PF09164.10 KFR00532.1 - 2 8.5 3.6 1.1 9.3 0.1 2.4 3 0 0 3 3 3 0 Vitamin D binding protein, domain III HPS3_C PF14763.6 KFR00533.1 - 6.6e-172 571.7 6.5 1.3e-171 570.7 6.5 1.5 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3, C-terminal HPS3_Mid PF14762.6 KFR00533.1 - 9.9e-170 564.5 4.2 1.5e-169 563.9 4.2 1.3 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3, middle region HPS3_N PF14761.6 KFR00533.1 - 1.8e-38 132.2 0.2 4.7e-38 130.8 0.2 1.8 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3 Tubulin PF00091.25 KFR00534.1 - 9.1e-68 228.3 0.0 1.2e-67 228.0 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFR00534.1 - 1e-51 174.4 0.0 1.6e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFR00534.1 - 0.0013 18.4 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain SNF2_N PF00176.23 KFR00535.1 - 3e-82 276.2 0.1 4.4e-82 275.6 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KFR00535.1 - 1.3e-19 69.9 0.0 2.9e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KFR00535.1 - 2.1e-13 50.6 0.0 1.5e-12 47.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 KFR00535.1 - 1.6e-08 34.3 8.8 3.8e-08 33.0 8.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFR00535.1 - 3.5e-08 33.2 7.3 8.6e-08 31.9 7.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFR00535.1 - 4e-08 33.0 9.4 9.4e-08 31.8 9.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFR00535.1 - 1.5e-07 31.3 6.9 4.8e-07 29.7 6.9 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFR00535.1 - 3.3e-07 30.1 7.9 9.4e-07 28.7 7.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFR00535.1 - 3.7e-07 30.4 9.0 3.7e-07 30.4 9.0 2.1 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 KFR00535.1 - 1.1e-05 25.2 8.7 2.7e-05 23.9 8.7 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFR00535.1 - 2e-05 24.7 10.1 4.8e-05 23.4 10.1 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING ResIII PF04851.15 KFR00535.1 - 3.5e-05 23.9 0.0 0.09 12.8 0.0 2.8 3 0 0 3 3 2 2 Type III restriction enzyme, res subunit zf-rbx1 PF12678.7 KFR00535.1 - 0.00015 21.9 3.4 0.0005 20.3 3.4 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFR00535.1 - 0.00037 20.5 0.7 0.0009 19.3 0.7 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KFR00535.1 - 0.071 12.9 3.0 0.17 11.7 3.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KFR00535.1 - 0.13 12.2 5.5 0.1 12.5 3.5 1.9 2 0 0 2 2 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 KFR00535.1 - 0.19 11.6 8.6 0.69 9.8 8.6 2.0 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF2385 PF09539.10 KFR00535.1 - 0.2 12.2 0.4 1e+02 3.5 0.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2385) DUF4171 PF13775.6 KFR00535.1 - 0.57 10.6 2.8 5.9 7.4 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4171) zf-RING_11 PF17123.5 KFR00535.1 - 0.6 9.9 6.3 1.5 8.6 6.3 1.8 1 0 0 1 1 1 0 RING-like zinc finger Rad50_zn_hook PF04423.14 KFR00535.1 - 1.3 8.9 4.2 1 9.2 0.5 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_10 PF16685.5 KFR00535.1 - 1.4 9.1 6.5 3.8 7.7 6.5 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 Glyco_transf_8 PF01501.20 KFR00536.1 - 1.4e-19 70.7 0.1 2.1e-09 37.3 0.0 2.4 2 1 1 3 3 3 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KFR00536.1 - 0.001 18.5 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 KFR00536.1 - 0.01 15.8 0.1 0.02 14.9 0.1 1.5 1 1 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Cystatin PF00031.21 KFR00537.1 - 7.4e-42 141.5 1.7 2.6e-22 78.9 0.1 2.2 2 0 0 2 2 2 2 Cystatin domain Cathelicidins PF00666.17 KFR00537.1 - 3.5e-15 56.1 2.7 1.1e-06 28.9 0.4 2.1 2 0 0 2 2 2 2 Cathelicidin SQAPI PF16845.5 KFR00537.1 - 7.1e-06 26.3 0.0 0.00013 22.2 0.0 2.2 2 0 0 2 2 2 1 Aspartic acid proteinase inhibitor Spp-24 PF07448.11 KFR00537.1 - 0.00071 19.7 2.3 0.16 12.2 0.7 2.5 2 0 0 2 2 2 2 Secreted phosphoprotein 24 (Spp-24) cystatin-like domain Cystatin PF00031.21 KFR00538.1 - 0.00018 21.7 0.1 0.35 11.2 0.0 2.4 2 0 0 2 2 2 2 Cystatin domain Cystatin PF00031.21 KFR00539.1 - 1.1e-24 86.5 0.0 1e-12 48.1 0.0 2.1 2 0 0 2 2 2 2 Cystatin domain Cathelicidins PF00666.17 KFR00539.1 - 5.9e-09 36.2 0.2 0.00025 21.3 0.0 2.2 2 0 0 2 2 2 2 Cathelicidin Spp-24 PF07448.11 KFR00539.1 - 0.0049 17.0 0.5 0.21 11.8 0.1 2.4 2 0 0 2 2 2 1 Secreted phosphoprotein 24 (Spp-24) cystatin-like domain Abhydro_lipase PF04083.16 KFR00539.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Peptidase_C48 PF02902.19 KFR00540.1 - 2.7e-43 148.3 1.6 5e-43 147.4 1.6 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DEK_C PF08766.11 KFR00540.1 - 0.023 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 DEK C terminal domain RNA_pol_Rpb8 PF03870.15 KFR00541.1 - 8.4e-44 149.1 0.1 9.4e-44 149.0 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KFR00541.1 - 0.00037 20.5 0.0 0.031 14.3 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G EPO_TPO PF00758.18 KFR00542.1 - 3.8e-26 92.0 0.2 4.5e-26 91.8 0.2 1.1 1 0 0 1 1 1 1 Erythropoietin/thrombopoietin CHRD PF07452.12 KFR00543.1 - 3.7e-27 95.6 0.1 7.8e-13 49.4 0.0 3.2 3 0 0 3 3 3 3 CHRD domain VWC PF00093.18 KFR00543.1 - 0.47 10.8 7.8 0.81 10.1 7.8 1.4 1 0 0 1 1 1 0 von Willebrand factor type C domain Amnionless PF14828.6 KFR00543.1 - 0.89 8.3 11.3 1.6 7.5 11.3 1.3 1 0 0 1 1 1 0 Amnionless CHRD PF07452.12 KFR00544.1 - 3.2e-06 28.1 0.0 3.4e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 CHRD domain Voltage_CLC PF00654.20 KFR00545.1 - 1.3e-86 291.1 24.8 1.3e-86 291.1 24.8 1.9 1 1 1 2 2 2 1 Voltage gated chloride channel FAM131 PF15010.6 KFR00546.1 - 1.7e-52 179.2 8.8 3.5e-51 174.9 8.8 2.3 1 1 0 1 1 1 1 Putative cell signalling MIF4G PF02854.19 KFR00547.1 - 2.3e-68 230.0 9.6 2.3e-68 230.0 9.6 1.8 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 KFR00547.1 - 1.2e-26 92.9 2.4 1.9e-26 92.2 0.2 2.6 3 1 0 3 3 3 1 MA3 domain RPN1_RPN2_N PF17781.1 KFR00548.1 - 6e-126 420.0 1.8 6e-126 420.0 1.8 1.9 3 0 0 3 3 3 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KFR00548.1 - 2.8e-32 110.5 0.3 5.7e-32 109.5 0.3 1.6 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KFR00548.1 - 6.5e-24 83.1 25.6 1.3e-06 28.6 0.1 8.7 10 0 0 10 10 10 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KFR00548.1 - 1.1e-05 25.8 0.0 0.12 12.8 0.0 4.3 4 1 1 5 5 5 2 HEAT repeats THAP PF05485.12 KFR00548.1 - 0.031 15.2 0.6 0.067 14.1 0.6 1.5 1 0 0 1 1 1 0 THAP domain Peptidase_M13_N PF05649.13 KFR00549.1 - 1.4e-123 413.4 0.9 1.8e-123 413.0 0.9 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFR00549.1 - 1.6e-34 119.3 1.3 1.7e-34 119.2 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M13 ALG3 PF05208.13 KFR00551.1 - 2.4e-140 468.0 9.1 2.9e-140 467.8 9.1 1.0 1 0 0 1 1 1 1 ALG3 protein EpsG PF14897.6 KFR00551.1 - 1.7e-08 34.1 9.7 1.7e-08 34.1 9.7 1.6 2 0 0 2 2 2 1 EpsG family VWA_3 PF13768.6 KFR00553.1 - 1.2e-14 54.6 0.0 1.8e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFR00553.1 - 1.4e-05 25.7 0.0 2.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KFR00553.1 - 0.003 17.8 0.0 0.004 17.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KFR00554.1 - 1.2e-18 66.7 0.4 5.4e-15 55.0 0.0 2.0 1 1 1 2 2 2 2 Vault protein inter-alpha-trypsin domain ABC_tran PF00005.27 KFR00555.1 - 4.3e-40 137.4 0.2 1.7e-19 70.7 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 KFR00555.1 - 1.5e-23 82.6 5.5 1.5e-23 82.6 5.5 2.8 3 1 0 3 3 1 1 ABC transporter AAA_21 PF13304.6 KFR00555.1 - 4.4e-12 46.4 0.9 0.0013 18.6 0.0 4.6 4 1 1 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFR00555.1 - 6.7e-10 38.8 1.9 0.00013 21.5 0.0 4.0 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KFR00555.1 - 4.4e-07 30.0 0.7 0.03 14.0 0.0 3.9 4 0 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 KFR00555.1 - 6.1e-06 26.6 0.6 0.027 14.7 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA PF00004.29 KFR00555.1 - 1.3e-05 25.6 0.5 0.18 12.2 0.0 3.4 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KFR00555.1 - 1.5e-05 24.6 0.0 0.011 15.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.12 KFR00555.1 - 1.6e-05 24.9 0.1 0.11 12.4 0.0 2.5 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.23 KFR00555.1 - 3.9e-05 23.7 0.0 0.043 13.9 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFR00555.1 - 0.00012 22.1 0.0 0.19 11.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 KFR00555.1 - 0.00027 20.7 0.0 0.99 9.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KFR00555.1 - 0.00065 20.1 0.1 0.7 10.2 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 KFR00555.1 - 0.0018 17.5 0.1 0.48 9.6 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain AAA_23 PF13476.6 KFR00555.1 - 0.002 18.7 12.8 0.39 11.2 0.0 3.9 3 1 0 4 4 4 2 AAA domain Dynamin_N PF00350.23 KFR00555.1 - 0.0021 18.1 0.2 0.071 13.2 0.0 3.1 3 0 0 3 3 3 1 Dynamin family RNA_helicase PF00910.22 KFR00555.1 - 0.0027 18.1 0.0 0.59 10.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 KFR00555.1 - 0.0055 16.4 0.0 1 9.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 KFR00555.1 - 0.006 16.8 0.0 2 8.6 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 KFR00555.1 - 0.0067 16.7 0.5 9.9 6.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain MobB PF03205.14 KFR00555.1 - 0.016 15.1 0.1 5.4 6.9 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 KFR00555.1 - 0.018 15.0 0.0 11 6.0 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 KFR00555.1 - 0.021 14.8 0.0 7.4 6.4 0.0 2.7 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.6 KFR00555.1 - 0.021 15.0 0.9 3.1 7.9 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.6 KFR00555.1 - 0.023 15.2 1.4 1.5 9.4 0.0 3.3 4 0 0 4 4 3 0 AAA domain AAA_14 PF13173.6 KFR00555.1 - 0.024 14.7 0.3 3.2 7.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain Septin PF00735.18 KFR00555.1 - 0.026 13.8 0.0 4.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Septin DUF87 PF01935.17 KFR00555.1 - 0.042 13.9 8.7 0.27 11.3 0.0 3.5 5 0 0 5 5 3 0 Helicase HerA, central domain DUF1672 PF07901.11 KFR00555.1 - 0.046 13.0 0.9 0.078 12.3 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) Arf PF00025.21 KFR00555.1 - 0.063 12.7 0.2 2 7.8 0.0 2.8 3 0 0 3 3 2 0 ADP-ribosylation factor family AAA_7 PF12775.7 KFR00555.1 - 0.069 12.7 0.0 4.3 6.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KFR00555.1 - 0.074 12.8 0.1 9 6.0 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.18 KFR00555.1 - 0.11 11.8 0.1 0.47 9.8 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family YiiD_C PF09500.10 KFR00555.1 - 0.12 12.2 0.1 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) cobW PF02492.19 KFR00555.1 - 0.12 11.9 0.0 10 5.6 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 KFR00555.1 - 0.13 11.8 0.1 8.6 5.9 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_13 PF13166.6 KFR00555.1 - 6 5.4 9.3 3 6.4 0.1 3.4 2 2 1 3 3 3 0 AAA domain Adap_comp_sub PF00928.21 KFR00556.1 - 7.3e-82 274.7 0.1 9.4e-82 274.3 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFR00556.1 - 7.1e-06 26.0 0.5 1.2e-05 25.3 0.5 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KFR00556.1 - 0.022 14.2 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Dsh_C PF12316.8 KFR00557.1 - 1.1e-80 270.9 33.0 1.1e-80 270.9 33.0 2.6 2 1 0 2 2 2 1 Segment polarity protein dishevelled (Dsh) C terminal Dishevelled PF02377.15 KFR00557.1 - 6.5e-67 225.0 23.1 6.5e-67 225.0 23.1 2.6 3 0 0 3 3 3 1 Dishevelled specific domain PDZ PF00595.24 KFR00557.1 - 8.8e-19 67.6 0.3 1.5e-18 66.9 0.3 1.4 1 0 0 1 1 1 1 PDZ domain DEP PF00610.21 KFR00557.1 - 3.3e-17 62.3 0.0 7.1e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DIX PF00778.17 KFR00557.1 - 7.9e-06 25.6 0.1 3.3e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 DIX domain PDZ_6 PF17820.1 KFR00557.1 - 4.5e-05 23.2 0.0 8.5e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFR00557.1 - 0.0061 16.9 0.1 0.012 16.0 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Shufflon_N PF04917.12 KFR00557.1 - 0.029 13.8 0.1 0.049 13.1 0.1 1.3 1 0 0 1 1 1 0 Bacterial shufflon protein, N-terminal constant region W2 PF02020.18 KFR00558.1 - 6.6e-19 67.8 2.1 6.6e-19 67.8 2.1 2.9 3 1 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 KFR00558.1 - 1.4e-12 46.8 5.6 0.00066 19.3 0.5 3.6 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 KFR00558.1 - 0.0034 15.6 0.8 0.0058 14.8 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) DUF4007 PF13182.6 KFR00558.1 - 0.048 12.8 0.3 1.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4007) VIR_N PF15912.5 KFR00558.1 - 0.12 12.0 3.1 0.21 11.2 3.1 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Hexapep_2 PF14602.6 KFR00558.1 - 0.53 10.1 11.5 0.55 10.0 4.2 3.7 2 1 2 4 4 4 0 Hexapeptide repeat of succinyl-transferase ABC_tran PF00005.27 KFR00559.1 - 7.9e-54 181.9 0.0 1.4e-31 109.8 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KFR00559.1 - 1e-48 166.3 32.1 2.1e-31 109.6 9.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KFR00559.1 - 9.1e-12 44.9 5.1 0.012 15.0 0.0 4.4 3 1 1 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFR00559.1 - 0.00025 20.9 10.1 3.2 7.5 0.3 4.3 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFR00559.1 - 0.00029 20.5 1.3 0.43 10.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KFR00559.1 - 0.0011 19.0 2.3 0.8 9.8 0.2 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 KFR00559.1 - 0.0014 18.7 1.1 0.045 13.8 0.0 3.0 2 0 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KFR00559.1 - 0.0053 16.7 0.8 0.25 11.3 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_7 PF12775.7 KFR00559.1 - 0.011 15.3 0.3 0.46 10.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 KFR00559.1 - 0.015 15.0 0.3 0.3 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KFR00559.1 - 0.019 15.3 0.0 9.8 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 KFR00559.1 - 0.031 13.6 0.9 1.5 8.1 0.1 2.7 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 KFR00559.1 - 0.038 13.6 1.6 0.083 12.5 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KFR00559.1 - 0.13 12.8 1.4 8.7 6.9 0.0 2.9 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 KFR00559.1 - 0.15 12.0 0.7 0.39 10.7 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 KFR00559.1 - 0.16 12.5 0.1 0.16 12.5 0.1 3.5 4 0 0 4 4 3 0 AAA domain LVIVD PF08309.11 KFR00559.1 - 0.17 11.2 0.1 0.41 10.0 0.1 1.6 1 0 0 1 1 1 0 LVIVD repeat IstB_IS21 PF01695.17 KFR00559.1 - 0.27 10.9 2.7 3.3 7.4 0.0 3.0 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_22 PF13401.6 KFR00559.1 - 1.2 9.5 11.5 27 5.0 0.8 4.2 2 2 1 3 3 3 0 AAA domain AAA_15 PF13175.6 KFR00559.1 - 3.4 7.3 7.7 6.9 6.3 0.3 3.1 3 0 0 3 3 3 0 AAA ATPase domain NB-ARC PF00931.22 KFR00559.1 - 3.7 6.6 6.7 4.9 6.2 0.4 3.0 3 1 0 3 3 3 0 NB-ARC domain DUF87 PF01935.17 KFR00559.1 - 4 7.5 7.8 2.2 8.3 0.3 2.8 2 1 0 2 2 2 0 Helicase HerA, central domain Peptidase_M1 PF01433.20 KFR00560.1 - 5.3e-40 137.3 0.0 1.1e-39 136.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KFR00560.1 - 2.7e-28 98.3 0.1 5.5e-28 97.3 0.1 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KFR00560.1 - 2.3e-10 41.0 0.4 4.4e-10 40.0 0.2 1.6 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF2268 PF10026.9 KFR00560.1 - 0.0081 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Predicted Zn-dependent protease (DUF2268) Peptidase_C2 PF00648.21 KFR00561.1 - 3.7e-81 272.4 0.0 5.3e-81 271.9 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KFR00561.1 - 8.4e-44 149.3 0.0 2.2e-21 76.6 0.0 2.8 2 1 0 2 2 2 2 Calpain large subunit, domain III p450 PF00067.22 KFR00562.1 - 7.6e-123 410.7 0.2 8.5e-123 410.5 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 MCM6_C PF18263.1 KFR00562.1 - 0.024 14.9 0.0 0.047 13.9 0.0 1.4 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain p450 PF00067.22 KFR00563.1 - 1e-121 407.0 0.0 1.1e-121 406.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFR00564.1 - 1.6e-121 406.3 0.0 1.8e-121 406.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2124 PF09897.9 KFR00564.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2124) IF4E PF01652.18 KFR00565.1 - 2.7e-60 202.8 0.1 3.3e-60 202.5 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Neur_chan_memb PF02932.16 KFR00566.1 - 1.3e-70 238.2 0.1 1.7e-70 237.8 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFR00566.1 - 1.3e-63 214.3 2.7 2e-63 213.8 2.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Trypsin PF00089.26 KFR00567.1 - 1.1e-44 152.9 0.0 1.2e-44 152.8 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFR00567.1 - 0.015 16.2 0.1 0.028 15.3 0.1 1.4 1 1 0 1 1 1 0 Trypsin-like peptidase domain AA_permease PF00324.21 KFR00568.1 - 8.2e-22 77.4 6.1 1e-21 77.2 6.1 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KFR00568.1 - 1.1e-20 74.0 0.1 4.3e-12 45.8 0.0 3.3 3 0 0 3 3 3 3 Solute carrier family 12 Peptidase_M13_N PF05649.13 KFR00569.1 - 3e-106 356.3 0.0 3.9e-106 356.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFR00569.1 - 2.5e-50 170.9 0.0 4.9e-50 170.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 ENTH PF01417.20 KFR00569.1 - 0.2 11.7 0.4 1.6 8.8 0.0 2.6 3 0 0 3 3 3 0 ENTH domain Alk_phosphatase PF00245.20 KFR00570.1 - 6.4e-165 549.1 0.2 7.3e-165 548.9 0.2 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 KFR00570.1 - 0.0026 17.2 0.2 0.0045 16.4 0.2 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Alk_phosphatase PF00245.20 KFR00571.1 - 7.6e-159 529.1 0.1 8.6e-159 528.9 0.1 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 KFR00571.1 - 0.004 16.6 0.0 0.0063 15.9 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily RNB PF00773.19 KFR00572.1 - 3.2e-100 335.6 0.0 4.1e-100 335.3 0.0 1.1 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KFR00572.1 - 2.6e-25 88.2 0.0 6.9e-25 86.9 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 KFR00572.1 - 2.7e-25 88.5 0.0 5.3e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal Rrp44_CSD1 PF17216.3 KFR00572.1 - 2.1e-10 40.5 0.0 1.5e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 Rrp44-like cold shock domain CSD2 PF17876.1 KFR00572.1 - 4.3e-05 23.6 0.0 0.033 14.4 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain CSN7a_helixI PF18392.1 KFR00573.1 - 5.9e-23 80.5 2.6 1.1e-22 79.6 2.6 1.5 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain PCI PF01399.27 KFR00573.1 - 1.1e-09 38.7 3.5 2.6e-09 37.5 0.3 2.2 2 0 0 2 2 2 1 PCI domain Band_3_cyto PF07565.13 KFR00573.1 - 0.03 14.1 5.2 0.057 13.2 5.2 1.4 1 1 0 1 1 1 0 Band 3 cytoplasmic domain GMP_PDE_delta PF05351.11 KFR00574.1 - 6.1e-44 149.9 0.1 1e-43 149.1 0.1 1.3 1 1 0 1 1 1 1 GMP-PDE, delta subunit RRM_1 PF00076.22 KFR00575.1 - 2.1e-66 219.7 7.2 6.5e-17 61.1 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 KFR00575.1 - 9.6e-05 22.2 0.2 0.35 10.6 0.0 4.0 4 0 0 4 4 4 2 Rrp7 RRM-like N-terminal domain Limkain-b1 PF11608.8 KFR00575.1 - 0.0012 18.9 1.1 1.8 8.7 0.0 4.0 4 0 0 4 4 4 1 Limkain b1 RRM_occluded PF16842.5 KFR00575.1 - 0.0017 18.2 0.4 0.7 9.8 0.0 3.3 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 KFR00575.1 - 0.0036 17.4 0.0 6.8 6.9 0.0 3.8 3 0 0 3 3 3 1 RNA recognition motif DbpA PF03880.15 KFR00575.1 - 0.0064 16.5 0.2 0.4 10.7 0.0 3.2 4 0 0 4 4 4 1 DbpA RNA binding domain Nup35_RRM_2 PF14605.6 KFR00575.1 - 0.042 13.8 0.1 1.7 8.7 0.0 3.2 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KFR00575.1 - 0.17 11.5 0.1 6.1 6.5 0.0 3.0 2 1 1 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 KFR00575.1 - 0.2 11.3 0.1 25 4.6 0.0 2.9 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated FOP_dimer PF09398.10 KFR00576.1 - 0.0053 17.0 0.0 0.043 14.1 0.0 2.6 2 0 0 2 2 2 1 FOP N terminal dimerisation domain CENP-B_dimeris PF09026.10 KFR00576.1 - 0.0099 16.3 3.0 0.0099 16.3 3.0 2.1 2 0 0 2 2 2 1 Centromere protein B dimerisation domain RPN2_C PF18004.1 KFR00577.1 - 1.7e-49 167.8 10.9 3.8e-49 166.7 10.9 1.6 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KFR00577.1 - 1.3e-42 142.1 19.5 5e-09 36.1 0.0 7.9 7 0 0 7 7 7 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KFR00577.1 - 2.3e-21 76.0 0.4 1.3e-14 54.4 0.0 5.5 4 1 1 6 6 6 2 HEAT repeats RPN1_RPN2_N PF17781.1 KFR00577.1 - 1.4e-08 34.6 0.1 3.8e-08 33.1 0.1 1.8 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain HEAT PF02985.22 KFR00577.1 - 7.2e-06 25.8 1.0 1.3 9.5 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 KFR00577.1 - 0.00047 20.6 1.5 0.52 10.9 0.0 5.0 5 1 2 7 7 6 2 HEAT-like repeat HEAT_PBS PF03130.16 KFR00577.1 - 0.0018 18.8 1.6 6.7 7.7 0.0 4.6 4 0 0 4 4 3 1 PBS lyase HEAT-like repeat PA26 PF04636.13 KFR00577.1 - 0.068 12.1 0.1 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Tim54 PF11711.8 KFR00577.1 - 0.3 9.8 7.7 0.47 9.2 7.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Vfa1 PF08432.10 KFR00577.1 - 0.84 9.9 12.7 3.5 7.9 12.0 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Pox_Ag35 PF03286.14 KFR00577.1 - 1.8 8.3 13.2 4.1 7.1 13.2 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NARP1 PF12569.8 KFR00577.1 - 4.5 6.1 11.4 10 4.9 11.4 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1764 PF08576.10 KFR00577.1 - 4.7 8.2 14.3 11 7.0 14.3 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) 7tm_1 PF00001.21 KFR00578.1 - 5.7e-66 222.5 14.5 7.8e-66 222.1 14.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR00578.1 - 4.3e-11 42.7 16.6 1.4e-10 41.0 16.6 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFR00578.1 - 1.1e-07 31.9 3.6 1.1e-07 31.9 3.6 2.2 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFR00578.1 - 2.7e-05 23.9 13.9 2.7e-05 23.9 13.9 2.4 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2385 PF09539.10 KFR00578.1 - 0.016 15.7 0.0 0.034 14.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) DUF1385 PF07136.11 KFR00578.1 - 0.076 12.3 0.0 0.076 12.3 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1385) zf-LITAF-like PF10601.9 KFR00578.1 - 1.3 9.4 4.4 1.4 9.2 1.1 2.9 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain Ribosomal_L35Ae PF01247.18 KFR00579.1 - 1.6e-46 156.4 0.4 1.8e-46 156.3 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae DUF2080 PF09853.9 KFR00579.1 - 0.024 14.4 0.4 0.1 12.3 0.0 2.2 2 1 0 2 2 2 0 Putative transposon-encoded protein (DUF2080) RimM PF01782.18 KFR00579.1 - 0.081 13.1 0.0 0.97 9.7 0.0 2.0 2 0 0 2 2 2 0 RimM N-terminal domain IQ PF00612.27 KFR00580.1 - 4.3e-05 23.0 0.1 0.00011 21.7 0.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif LRR_8 PF13855.6 KFR00581.1 - 3.5e-23 81.1 11.4 2.1e-08 33.8 1.5 3.5 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFR00581.1 - 3.3e-17 62.3 19.5 0.00012 22.4 0.1 5.3 3 2 2 5 5 5 5 Leucine Rich repeats (2 copies) CH PF00307.31 KFR00581.1 - 9e-10 38.7 0.0 1.9e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain LRR_6 PF13516.6 KFR00581.1 - 0.00081 19.2 13.0 0.62 10.3 0.0 5.8 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 KFR00581.1 - 0.0056 17.0 22.1 30 5.7 0.7 8.2 9 0 0 9 9 9 0 Leucine Rich Repeat CAMSAP_CH PF11971.8 KFR00581.1 - 0.017 15.0 0.0 0.055 13.3 0.0 1.9 1 0 0 1 1 1 0 CAMSAP CH domain LRR_9 PF14580.6 KFR00581.1 - 7 6.1 6.9 6.8 6.2 2.6 2.7 2 1 2 4 4 4 0 Leucine-rich repeat FYTT PF07078.11 KFR00582.1 - 6.9e-124 413.2 21.0 7.8e-124 413.0 21.0 1.0 1 0 0 1 1 1 1 Forty-two-three protein zf-RING_9 PF13901.6 KFR00583.1 - 2.9e-70 236.4 14.8 2.9e-70 236.4 14.8 1.8 2 0 0 2 2 2 1 Putative zinc-RING and/or ribbon RUN PF02759.19 KFR00583.1 - 4.1e-08 33.3 0.7 9.3e-08 32.1 0.7 1.6 1 0 0 1 1 1 1 RUN domain DNA_photolyase PF00875.18 KFR00584.1 - 1.3e-20 74.1 0.0 2.4e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase FAD_binding_7 PF03441.14 KFR00584.1 - 0.028 13.9 0.2 0.057 12.9 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain of DNA photolyase NIDO PF06119.14 KFR00585.1 - 2.1e-10 41.4 0.6 4.1e-10 40.5 0.6 1.5 1 0 0 1 1 1 1 Nidogen-like NIDO PF06119.14 KFR00588.1 - 3e-11 44.1 1.0 8.3e-11 42.7 0.1 1.9 2 1 0 2 2 2 1 Nidogen-like Peptidase_M28 PF04389.17 KFR00589.1 - 6.4e-14 52.1 0.0 1.2e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.15 KFR00589.1 - 3e-10 40.2 0.1 7e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.22 KFR00589.1 - 2.4e-08 33.9 0.0 9.8e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 PA domain Solute_trans_a PF03619.16 KFR00590.1 - 5.4e-40 137.6 13.8 6.6e-40 137.3 13.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha YmcE_antitoxin PF15939.5 KFR00590.1 - 0.18 11.9 2.6 0.49 10.6 2.6 1.7 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system CTP_transf_like PF01467.26 KFR00591.1 - 1.3e-31 109.7 0.7 2.5e-31 108.8 0.0 1.7 2 0 0 2 2 2 1 Cytidylyltransferase-like DUF1664 PF07889.12 KFR00591.1 - 0.055 13.5 0.6 0.092 12.8 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) KH_5 PF13184.6 KFR00591.1 - 0.056 13.5 0.5 0.16 12.0 0.5 1.7 1 0 0 1 1 1 0 NusA-like KH domain YtxH PF12732.7 KFR00591.1 - 0.24 11.9 2.5 0.46 11.1 2.5 1.4 1 0 0 1 1 1 0 YtxH-like protein AKNA PF12443.8 KFR00591.1 - 0.39 11.4 2.7 0.54 11.0 0.8 2.1 2 0 0 2 2 2 0 AT-hook-containing transcription factor DUF3678 PF12435.8 KFR00591.1 - 2.4 7.6 6.2 0.81 9.1 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Tctex-1 PF03645.13 KFR00592.1 - 3.7e-26 91.3 0.0 4.2e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family Trans_coact PF16805.5 KFR00592.1 - 0.082 13.0 0.4 0.51 10.5 0.0 2.0 1 1 1 2 2 2 0 Phage late-transcription coactivator V-set PF07686.17 KFR00593.1 - 7.2e-08 32.6 0.0 1.1e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFR00593.1 - 0.00016 21.7 0.0 0.00028 20.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR00593.1 - 0.00038 21.0 0.0 0.00085 19.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFR00593.1 - 0.0023 18.1 0.0 0.0044 17.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFR00593.1 - 0.01 16.2 0.1 0.026 14.9 0.1 1.7 1 1 0 1 1 1 0 Immunoglobulin domain G6B PF15096.6 KFR00593.1 - 0.21 11.4 0.0 23 4.7 0.0 2.5 1 1 0 2 2 2 0 G6B family Trypsin PF00089.26 KFR00594.1 - 7.5e-57 192.7 0.0 1.1e-56 192.1 0.0 1.3 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 KFR00594.1 - 3.1e-50 169.1 1.1 7.9e-29 100.2 0.2 2.6 2 0 0 2 2 2 2 CUB domain Sushi PF00084.20 KFR00594.1 - 3.4e-15 56.4 17.9 1.4e-09 38.4 0.3 4.8 5 0 0 5 5 5 2 Sushi repeat (SCR repeat) FXa_inhibition PF14670.6 KFR00594.1 - 1.1e-08 35.2 10.8 5.7e-08 32.9 8.4 2.9 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site CUB_2 PF02408.20 KFR00594.1 - 7.5e-06 25.7 0.1 0.019 14.7 0.0 2.9 3 0 0 3 3 3 2 CUB-like domain EGF_CA PF07645.15 KFR00594.1 - 8.7e-06 25.9 9.0 2.8e-05 24.2 7.9 2.5 2 0 0 2 2 2 1 Calcium-binding EGF domain Trypsin_2 PF13365.6 KFR00594.1 - 0.00013 22.9 0.1 0.00026 21.9 0.1 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain cEGF PF12662.7 KFR00594.1 - 0.00044 20.1 6.5 0.0042 17.0 3.9 3.0 2 0 0 2 2 2 1 Complement Clr-like EGF-like DUF1986 PF09342.11 KFR00594.1 - 0.027 14.9 0.1 0.063 13.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) DUF2244 PF10003.9 KFR00594.1 - 0.21 11.3 0.1 0.36 10.5 0.1 1.3 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Somatostatin PF03002.15 KFR00595.1 - 1.1e-12 47.6 8.4 1.5e-12 47.2 8.4 1.2 1 0 0 1 1 1 1 Somatostatin/Cortistatin family BTB PF00651.31 KFR00596.1 - 4.1e-27 94.6 0.3 6.9e-27 93.9 0.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFR00596.1 - 6.2e-23 80.1 53.7 8.3e-07 29.2 0.5 7.1 8 0 0 8 8 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFR00596.1 - 6.6e-18 64.1 58.3 3.7e-05 23.9 0.3 7.5 7 0 0 7 7 6 6 Zinc finger, C2H2 type zf-met PF12874.7 KFR00596.1 - 2.8e-11 43.4 30.9 0.0081 16.5 0.1 7.1 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFR00596.1 - 8.5e-11 41.7 56.5 0.012 16.4 1.1 7.7 7 0 0 7 7 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFR00596.1 - 2.6e-05 24.4 19.9 0.41 11.0 2.0 6.3 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFR00596.1 - 0.021 14.6 0.9 0.021 14.6 0.9 7.3 6 2 0 6 6 6 0 C2H2-type zinc-finger domain Zn-ribbon_8 PF09723.10 KFR00596.1 - 0.032 14.3 1.3 0.032 14.3 1.3 5.7 4 3 3 7 7 7 0 Zinc ribbon domain DUF3342 PF11822.8 KFR00596.1 - 0.033 14.4 0.4 0.074 13.2 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) zf-C2H2_6 PF13912.6 KFR00596.1 - 0.039 14.0 0.1 0.039 14.0 0.1 6.5 7 0 0 7 7 6 0 C2H2-type zinc finger zf-C2HE PF16278.5 KFR00596.1 - 0.046 14.2 37.3 0.19 12.2 0.3 6.9 1 1 5 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 KFR00596.1 - 0.081 12.7 0.3 0.081 12.7 0.3 6.4 7 0 0 7 7 6 0 zinc-finger C2H2-type DUF3268 PF11672.8 KFR00596.1 - 0.86 10.0 14.2 1 9.7 0.3 4.0 3 1 1 4 4 4 0 zinc-finger-containing domain GAGA PF09237.11 KFR00596.1 - 1.3 8.9 17.2 7.2 6.5 0.0 5.1 1 1 4 5 5 5 0 GAGA factor LIM PF00412.22 KFR00598.1 - 8.9e-37 125.1 28.1 2.1e-14 53.5 6.9 3.1 3 0 0 3 3 3 3 LIM domain Mut7-C PF01927.16 KFR00598.1 - 0.05 13.7 0.8 0.05 13.7 0.8 3.4 2 1 1 3 3 3 0 Mut7-C RNAse domain DUF2685 PF10886.8 KFR00598.1 - 0.85 9.9 6.3 12 6.1 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2685) zf-dskA_traR PF01258.17 KFR00598.1 - 1.2 9.1 0.1 1.2 9.1 0.1 6.2 7 1 0 7 7 7 0 Prokaryotic dksA/traR C4-type zinc finger P53 PF00870.18 KFR00599.1 - 2.9e-65 219.7 1.2 2.9e-65 219.7 0.0 1.6 2 0 0 2 2 2 1 P53 DNA-binding domain P53_tetramer PF07710.11 KFR00599.1 - 6.9e-19 66.9 0.4 1.9e-18 65.5 0.2 1.8 2 0 0 2 2 2 1 P53 tetramerisation motif SAM_2 PF07647.17 KFR00599.1 - 4.5e-10 39.5 0.0 8.6e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFR00599.1 - 0.025 15.0 0.0 0.066 13.7 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF2357 PF09823.9 KFR00599.1 - 0.18 11.0 2.4 0.42 9.8 2.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) 2OG-FeII_Oxy_3 PF13640.6 KFR00600.1 - 4.3e-11 43.6 0.0 1.9e-10 41.5 0.0 2.2 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KFR00600.1 - 2.6e-09 37.5 0.0 1.8e-08 34.8 0.0 2.4 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily Fis1_TPR_C PF14853.6 KFR00600.1 - 0.0029 17.7 1.2 0.01 15.9 0.1 2.3 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 KFR00600.1 - 0.0073 16.3 7.0 1.2 9.5 0.5 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFR00600.1 - 0.017 15.0 6.5 0.97 9.4 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat YfiO PF13525.6 KFR00600.1 - 0.031 14.0 5.7 0.42 10.3 0.1 2.9 3 0 0 3 3 3 0 Outer membrane lipoprotein Oxygenase-NA PF09859.9 KFR00600.1 - 0.038 13.5 0.0 0.51 9.8 0.0 2.3 1 1 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA TPR_7 PF13176.6 KFR00600.1 - 0.039 14.0 3.2 12 6.2 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFR00600.1 - 0.068 14.0 1.2 1.5 9.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFR00600.1 - 0.67 10.6 2.4 1.3e+02 3.3 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat PMP22_Claudin PF00822.20 KFR00601.1 - 1.4e-49 168.2 10.5 1.6e-49 168.0 10.5 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFR00601.1 - 1.4e-10 41.3 12.9 8.4e-10 38.7 12.4 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF4134 PF13572.6 KFR00601.1 - 0.0071 16.6 3.0 0.0071 16.6 3.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4134) DUF981 PF06168.11 KFR00601.1 - 0.01 15.8 5.2 0.38 10.7 5.5 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF981) CD20 PF04103.15 KFR00601.1 - 0.017 15.2 1.4 0.017 15.2 1.4 2.6 2 1 1 3 3 3 0 CD20-like family SUR7 PF06687.12 KFR00601.1 - 0.059 13.0 6.4 0.026 14.2 3.4 1.7 1 1 1 2 2 2 0 SUR7/PalI family Cytochrom_B_C PF00032.17 KFR00601.1 - 0.074 13.3 2.1 0.095 13.0 0.5 1.9 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD OppC_N PF12911.7 KFR00601.1 - 0.12 12.4 0.1 0.12 12.4 0.1 3.0 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C DUF2157 PF09925.9 KFR00601.1 - 0.39 10.5 0.1 0.39 10.5 0.1 3.2 4 0 0 4 4 4 0 Predicted membrane protein (DUF2157) Gram_pos_anchor PF00746.21 KFR00601.1 - 0.41 10.6 8.2 15 5.6 0.0 3.7 3 0 0 3 3 3 0 LPXTG cell wall anchor motif DUF1218 PF06749.12 KFR00601.1 - 0.53 10.8 9.0 0.66 10.5 2.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) DUF898 PF05987.13 KFR00601.1 - 2.3 7.2 10.9 0.21 10.6 3.2 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF898) DUF4131 PF13567.6 KFR00601.1 - 5.5 6.6 7.0 2.4 7.8 0.3 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) PMP22_Claudin PF00822.20 KFR00602.1 - 1e-18 67.7 7.4 1.4e-18 67.3 7.4 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFR00602.1 - 1.5e-06 28.1 12.0 6.9e-06 26.0 12.0 1.9 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DuoxA PF10204.9 KFR00602.1 - 0.012 14.7 2.1 0.019 14.0 2.1 1.4 1 0 0 1 1 1 0 Dual oxidase maturation factor Phage_holin_3_6 PF07332.11 KFR00602.1 - 9.2 6.3 11.9 3.8 7.6 2.9 3.0 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III TMEM52 PF14979.6 KFR00603.1 - 9.6e-06 25.6 13.0 6.3e-05 22.9 13.0 1.9 1 1 0 1 1 1 1 Transmembrane 52 Hum_adeno_E3A PF05393.11 KFR00603.1 - 0.081 12.9 1.9 0.12 12.4 1.9 1.3 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein TMIE PF16038.5 KFR00603.1 - 0.44 10.4 3.3 0.67 9.8 3.3 1.2 1 0 0 1 1 1 0 TMIE protein WBP-1 PF11669.8 KFR00603.1 - 3.2 8.4 11.7 17 6.1 11.7 2.0 1 1 0 1 1 1 0 WW domain-binding protein 1 TIR PF01582.20 KFR00604.1 - 2.5e-27 95.8 0.0 4.4e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 TIR domain Ig_6 PF18452.1 KFR00604.1 - 6.6e-21 73.6 2.3 3.5e-20 71.3 0.1 2.7 3 0 0 3 3 3 1 Immunoglobulin domain Ig_3 PF13927.6 KFR00604.1 - 7.6e-18 64.9 1.6 2.7e-09 37.5 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFR00604.1 - 3.5e-13 49.5 1.0 2.2e-06 27.7 0.1 3.7 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KFR00604.1 - 9.1e-11 41.9 1.0 0.0055 17.0 0.1 3.7 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFR00604.1 - 1.5e-10 41.0 0.2 0.00024 21.1 0.1 3.6 3 0 0 3 3 3 3 Immunoglobulin I-set domain TIR_2 PF13676.6 KFR00604.1 - 3e-10 40.7 0.0 6.6e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 TIR domain RBD-FIP PF09457.10 KFR00605.1 - 0.0038 17.1 2.8 0.0078 16.1 2.8 1.4 1 0 0 1 1 1 1 FIP domain Musclin PF11037.8 KFR00606.1 - 4.9e-62 207.7 0.1 5.5e-62 207.6 0.1 1.0 1 0 0 1 1 1 1 Insulin-resistance promoting peptide in skeletal muscle ANP PF00212.18 KFR00606.1 - 0.00026 21.1 0.6 0.44 10.8 0.0 2.4 2 0 0 2 2 2 2 Atrial natriuretic peptide Urotensin_II PF02083.15 KFR00607.1 - 0.00013 21.4 4.8 0.00022 20.7 4.8 1.4 1 0 0 1 1 1 1 Urotensin II Dynactin_p22 PF07426.11 KFR00607.1 - 0.011 15.6 2.2 0.69 9.7 0.3 2.1 2 0 0 2 2 2 0 Dynactin subunit p22 CCDC50_N PF15295.6 KFR00608.1 - 1.3e-47 161.1 41.0 2e-41 141.1 26.8 2.4 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 50 N-terminus FGF PF00167.18 KFR00610.1 - 8e-38 129.4 0.0 1.1e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 Fibroblast growth factor CDtoxinA PF03498.14 KFR00610.1 - 0.067 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain Mab-21 PF03281.14 KFR00611.1 - 1.6e-33 116.3 0.2 2e-33 115.9 0.2 1.2 1 0 0 1 1 1 1 Mab-21 protein LRAT PF04970.13 KFR00612.1 - 1.1e-34 119.5 0.0 1.3e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 Lecithin retinol acyltransferase Peptidase_C97 PF05903.14 KFR00612.1 - 0.025 14.4 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 PPPDE putative peptidase domain NLPC_P60 PF00877.19 KFR00612.1 - 0.056 13.5 0.0 0.085 12.9 0.0 1.3 1 0 0 1 1 1 0 NlpC/P60 family E1-E2_ATPase PF00122.20 KFR00613.1 - 4.9e-36 123.9 0.0 1.3e-35 122.6 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.8 KFR00613.1 - 9.5e-32 109.7 1.7 2.2e-31 108.6 1.7 1.7 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 KFR00613.1 - 9.2e-13 49.0 0.0 2.8e-08 34.3 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFR00613.1 - 1.2e-07 31.3 0.0 4.4e-07 29.5 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KFR00613.1 - 0.00022 21.3 0.0 0.00056 19.9 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) DUF2620 PF10941.8 KFR00613.1 - 0.17 12.1 0.0 0.95 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF2620 TcpE PF12648.7 KFR00613.1 - 0.18 12.3 7.2 0.028 14.9 1.6 2.5 2 0 0 2 2 2 0 TcpE family Dynamin_N PF00350.23 KFR00614.1 - 1.6e-38 132.4 0.2 1.6e-38 132.4 0.2 3.0 4 0 0 4 4 4 1 Dynamin family MMR_HSR1 PF01926.23 KFR00614.1 - 1e-05 25.6 0.2 0.00019 21.5 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFR00614.1 - 0.00016 21.2 0.0 0.011 15.3 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Roc PF08477.13 KFR00614.1 - 0.0072 16.5 0.0 0.62 10.3 0.0 2.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF1593 PF07632.11 KFR00614.1 - 0.013 15.0 0.1 0.013 15.0 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1593) Ras PF00071.22 KFR00614.1 - 0.027 14.1 0.0 8.2 6.0 0.0 2.6 2 0 0 2 2 2 0 Ras family AAA_16 PF13191.6 KFR00614.1 - 0.044 14.2 0.1 0.74 10.2 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain PilO PF04350.13 KFR00614.1 - 0.055 13.6 1.8 11 6.1 0.0 3.1 3 0 0 3 3 3 0 Pilus assembly protein, PilO Ephrin_rec_like PF07699.13 KFR00614.1 - 0.16 11.8 0.6 0.38 10.5 0.6 1.6 1 0 0 1 1 1 0 Putative ephrin-receptor like ImpA_N PF06812.12 KFR00614.1 - 0.33 11.1 3.1 4.2 7.5 0.0 3.2 2 0 0 2 2 2 0 ImpA, N-terminal, type VI secretion system FlaC_arch PF05377.11 KFR00614.1 - 8.6 6.8 7.9 37 4.8 1.9 3.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) LRR_8 PF13855.6 KFR00615.1 - 4.3e-84 276.2 57.7 3.5e-17 61.9 0.2 7.3 1 1 5 7 7 7 7 Leucine rich repeat LRR_5 PF13306.6 KFR00615.1 - 8.1e-35 119.6 0.0 1.1e-10 41.6 0.0 3.6 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFR00615.1 - 1.9e-34 117.1 39.1 0.00012 22.4 0.5 8.5 5 2 3 9 9 9 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFR00615.1 - 4.5e-20 71.9 12.4 0.00035 20.1 1.1 5.7 1 1 5 6 6 6 5 Leucine-rich repeat LRR_1 PF00560.33 KFR00615.1 - 5.6e-10 38.4 42.1 0.11 13.1 0.1 12.7 10 1 1 11 11 11 3 Leucine Rich Repeat Syndecan PF01034.20 KFR00615.1 - 0.015 15.2 2.4 0.027 14.4 2.4 1.3 1 0 0 1 1 1 0 Syndecan domain SAM_3 PF18016.1 KFR00615.1 - 0.051 13.4 0.1 0.3 10.9 0.0 2.3 2 1 1 3 3 3 0 SAM domain (Sterile alpha motif) TMEM132D_C PF15706.5 KFR00615.1 - 0.12 12.1 0.1 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Mid2 PF04478.12 KFR00615.1 - 0.23 11.3 0.0 0.36 10.6 0.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor P5-ATPase PF12409.8 KFR00616.1 - 5.5e-38 129.9 0.5 1.8e-37 128.2 0.5 2.0 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KFR00616.1 - 2.9e-36 124.7 0.1 2.9e-36 124.7 0.1 3.1 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 KFR00616.1 - 2.6e-16 60.6 0.2 2.6e-10 40.9 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFR00616.1 - 5.7e-07 29.5 0.0 1.3e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFR00616.1 - 1.8e-06 27.5 0.0 4.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus FapA PF03961.13 KFR00616.1 - 0.088 11.4 0.0 0.14 10.7 0.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A MMR_HSR1 PF01926.23 KFR00617.1 - 5.6e-15 55.4 0.1 3e-13 49.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFR00617.1 - 4.6e-08 33.1 0.1 0.0097 15.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KFR00617.1 - 1.5e-06 27.8 0.1 0.00052 19.6 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B AIG1 PF04548.16 KFR00617.1 - 0.00091 18.6 0.0 0.0023 17.3 0.0 1.7 1 0 0 1 1 1 1 AIG1 family cobW PF02492.19 KFR00617.1 - 0.021 14.4 0.3 0.17 11.5 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 KFR00617.1 - 1.2 9.4 4.8 3 8.2 0.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 KFR00617.1 - 2.4 8.2 7.6 2.3 8.3 0.3 3.3 3 1 1 4 4 4 0 Dynamin family BUD22 PF09073.10 KFR00617.1 - 5.6 6.2 19.3 2.8 7.2 15.7 2.0 2 0 0 2 2 2 0 BUD22 PID_2 PF14719.6 KFR00618.1 - 3.6e-74 248.6 0.6 4.8e-74 248.2 0.6 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.23 KFR00618.1 - 7.3e-05 22.8 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Glyco_transf_8 PF01501.20 KFR00619.1 - 9.4e-08 31.9 0.1 1.2e-07 31.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 BAR_3 PF16746.5 KFR00620.1 - 9.6e-81 271.0 14.8 1.7e-80 270.2 14.8 1.4 1 0 0 1 1 1 1 BAR domain of APPL family ArfGap PF01412.18 KFR00620.1 - 3.2e-40 136.9 0.1 3.2e-40 136.9 0.1 2.5 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf Ank_2 PF12796.7 KFR00620.1 - 4.9e-15 55.9 0.9 1.3e-08 35.3 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) PH PF00169.29 KFR00620.1 - 1.4e-14 54.5 0.6 1.4e-14 54.5 0.6 1.9 2 0 0 2 2 2 1 PH domain Ank_5 PF13857.6 KFR00620.1 - 1e-09 38.5 0.5 2.1e-06 27.9 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFR00620.1 - 3.4e-07 30.4 0.3 0.062 13.8 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 KFR00620.1 - 4.1e-06 26.7 0.1 0.03 14.9 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KFR00620.1 - 0.00011 22.7 0.1 0.023 15.3 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) PH_8 PF15409.6 KFR00620.1 - 0.07 13.4 0.2 0.24 11.7 0.2 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 KFR00620.1 - 0.16 12.4 8.2 0.45 11.0 3.3 3.1 2 1 0 2 2 2 0 Pleckstrin homology domain IPP-2 PF04979.14 KFR00621.1 - 3.6e-40 137.8 12.8 4.8e-40 137.4 12.8 1.1 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) CDC27 PF09507.10 KFR00621.1 - 0.34 10.2 15.2 0.38 10.1 15.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DNA_pol_phi PF04931.13 KFR00621.1 - 6.2 4.8 16.4 8 4.4 16.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Lipocalin PF00061.23 KFR00622.1 - 8.3e-23 81.2 0.1 9.5e-23 81.0 0.1 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.12 KFR00622.1 - 4.2e-22 78.7 0.0 6e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain VDE PF07137.11 KFR00622.1 - 1e-06 28.5 0.0 1.3e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 VDE lipocalin domain Triabin PF03973.13 KFR00622.1 - 0.00013 21.9 0.3 0.00029 20.7 0.3 1.7 1 1 0 1 1 1 1 Triabin adh_short PF00106.25 KFR00624.1 - 1.5e-44 151.8 0.0 1.7e-44 151.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFR00624.1 - 3.2e-27 95.6 0.0 4.2e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFR00624.1 - 4.1e-07 30.1 0.0 5.3e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 KR domain NRBF2 PF08961.10 KFR00624.1 - 0.17 11.5 0.1 0.23 11.1 0.1 1.1 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator adh_short PF00106.25 KFR00625.1 - 1e-41 142.6 0.0 1.3e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFR00625.1 - 9.3e-26 90.8 0.0 1.3e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFR00625.1 - 6e-08 32.8 0.0 9.5e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFR00625.1 - 5.4e-06 26.0 0.0 2.2e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Guanylate_kin PF00625.21 KFR00626.1 - 5.7e-66 221.7 1.4 9.4e-66 221.0 1.4 1.4 1 0 0 1 1 1 1 Guanylate kinase PDZ PF00595.24 KFR00626.1 - 5.5e-64 212.5 9.0 1.4e-20 73.4 0.2 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 KFR00626.1 - 2e-30 104.4 2.7 6e-11 42.0 0.1 3.8 3 0 0 3 3 3 3 PDZ domain PDZ_assoc PF10600.9 KFR00626.1 - 6.3e-29 100.6 5.1 6.3e-29 100.6 5.1 2.1 2 0 0 2 2 2 1 PDZ-associated domain of NMDA receptors MAGUK_N_PEST PF10608.9 KFR00626.1 - 3.7e-19 69.3 10.7 2.1e-14 54.0 3.4 2.7 1 1 1 2 2 2 2 Polyubiquitination (PEST) N-terminal domain of MAGUK PDZ_2 PF13180.6 KFR00626.1 - 2.6e-18 66.1 2.9 2.9e-05 24.3 0.0 4.0 4 0 0 4 4 4 3 PDZ domain SH3_1 PF00018.28 KFR00626.1 - 2.5e-08 33.4 0.1 7.5e-08 31.9 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFR00626.1 - 3.9e-08 32.9 0.0 1e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFR00626.1 - 0.032 14.1 0.0 0.12 12.2 0.0 2.1 1 0 0 1 1 1 0 Variant SH3 domain DUF1638 PF07796.11 KFR00626.1 - 0.09 12.8 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1638) Transferrin PF00405.17 KFR00627.1 - 3.8e-222 736.3 10.8 1.6e-116 389.0 1.0 2.0 2 0 0 2 2 2 2 Transferrin Phosphonate-bd PF12974.7 KFR00627.1 - 1.9e-12 47.3 0.0 5e-05 23.0 0.0 2.9 2 2 0 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 KFR00627.1 - 0.0072 15.8 0.0 1.8 7.9 0.0 2.6 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 Jiv90 PF14901.6 KFR00627.1 - 0.013 15.6 0.2 5.9 7.1 0.0 3.6 3 0 0 3 3 3 0 Cleavage inducing molecular chaperone IL12p40_C PF10420.9 KFR00627.1 - 0.22 12.1 8.3 5 7.7 1.1 2.9 2 0 0 2 2 2 0 Cytokine interleukin-12p40 C-terminus Glyco_transf_22 PF03901.17 KFR00629.1 - 7.4e-51 173.7 24.4 9.4e-51 173.3 24.4 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Peptidase_M14 PF00246.24 KFR00631.1 - 3.8e-95 319.0 0.0 4.8e-95 318.7 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KFR00631.1 - 5.8e-21 74.7 1.3 1.4e-20 73.4 1.3 1.7 1 0 0 1 1 1 1 Carboxypeptidase activation peptide 7tm_1 PF00001.21 KFR00632.1 - 1.1e-55 188.9 24.5 1.1e-55 188.9 24.5 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR00632.1 - 5.5e-09 35.8 27.4 8.1e-09 35.2 27.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFR00632.1 - 2.4 7.7 34.6 0.12 11.9 26.2 2.2 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx zf_ZIC PF18366.1 KFR00633.1 - 3e-29 100.9 4.7 3.8e-28 97.3 0.9 3.1 3 0 0 3 3 3 1 Zic proteins zinc finger domain zf-C2H2 PF00096.26 KFR00633.1 - 6.7e-11 42.0 16.0 6e-06 26.4 0.2 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFR00633.1 - 2.1e-09 37.4 9.4 8.9e-08 32.2 0.3 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR00633.1 - 7.6e-09 35.7 7.3 0.0075 17.0 0.2 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFR00633.1 - 0.0051 16.8 1.2 2.7 8.1 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFR00633.1 - 0.0097 16.2 3.9 0.28 11.5 0.1 3.0 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KFR00633.1 - 0.05 13.9 1.4 1.2 9.5 0.4 2.6 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-Di19 PF05605.12 KFR00633.1 - 2 8.8 8.6 1.5 9.1 1.9 3.0 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FOXP-CC PF16159.5 KFR00633.1 - 2.6 8.7 8.4 23 5.7 0.1 3.5 2 1 1 3 3 3 0 FOXP coiled-coil domain MGC-24 PF05283.11 KFR00633.1 - 6.6 7.2 8.4 12 6.4 0.1 2.6 2 1 1 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin zf_ZIC PF18366.1 KFR00634.1 - 1.2e-27 95.8 6.5 5.1e-27 93.7 0.9 2.9 3 0 0 3 3 3 1 Zic proteins zinc finger domain zf-H2C2_2 PF13465.6 KFR00634.1 - 4.9e-09 36.2 9.8 6.6e-08 32.6 0.3 4.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFR00634.1 - 1.5e-08 34.6 3.1 4.4e-06 26.8 0.2 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR00634.1 - 0.00025 21.6 1.1 0.0055 17.4 0.2 4.9 5 0 0 5 5 5 3 C2H2-type zinc finger Scramblase PF03803.15 KFR00635.1 - 1.4e-70 237.0 0.1 1.6e-70 236.9 0.1 1.0 1 0 0 1 1 1 1 Scramblase DUF4413 PF14372.6 KFR00635.1 - 0.096 13.1 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Scramblase PF03803.15 KFR00636.1 - 2.3e-88 295.2 0.0 2.5e-88 295.1 0.0 1.0 1 0 0 1 1 1 1 Scramblase Aldolase_II PF00596.21 KFR00644.1 - 2.4e-09 37.4 0.0 4.3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain GerD PF17898.1 KFR00644.1 - 0.07 13.1 0.7 0.19 11.7 0.7 1.7 1 0 0 1 1 1 0 Spore germination GerD central core domain Guanylate_kin PF00625.21 KFR00655.1 - 1.5e-62 210.5 0.1 2e-62 210.1 0.1 1.2 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.17 KFR00655.1 - 6.4e-13 48.2 0.0 1.2e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFR00655.1 - 1.7e-08 33.9 0.9 4.5e-08 32.6 0.9 1.8 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFR00655.1 - 1.9e-05 24.4 0.0 4.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain 7tm_1 PF00001.21 KFR00656.1 - 2e-16 60.1 24.9 1.8e-09 37.3 3.4 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) Renin_r PF07850.14 KFR00656.1 - 0.032 14.8 1.4 0.12 13.0 1.4 2.0 1 0 0 1 1 1 0 Renin receptor-like protein DUF1041 PF06292.17 KFR00656.1 - 0.098 13.1 0.2 0.21 12.0 0.2 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) Amino_oxidase PF01593.24 KFR00657.1 - 3.3e-69 234.3 0.0 3.9e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFR00657.1 - 8.6e-10 38.7 0.0 2.6e-09 37.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KFR00658.1 - 8e-51 173.7 0.0 9.7e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase C1q PF00386.21 KFR00660.1 - 1.5e-15 57.6 0.2 1.4e-14 54.4 0.2 2.0 1 1 0 1 1 1 1 C1q domain OCRE PF17780.1 KFR00660.1 - 0.0071 16.3 0.6 0.013 15.5 0.6 1.4 1 0 0 1 1 1 1 OCRE domain GerPB PF10803.8 KFR00660.1 - 0.16 12.0 0.1 2.6 8.2 0.0 2.5 2 1 0 2 2 2 0 Spore germination GerPB LNS2 PF08235.13 KFR00661.1 - 1.7e-103 345.0 0.0 4.3e-103 343.7 0.0 1.7 2 0 0 2 2 2 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KFR00661.1 - 1.2e-44 150.4 0.1 2.3e-44 149.5 0.1 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 KFR00661.1 - 4.1e-34 116.8 0.1 1.1e-33 115.3 0.1 1.8 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain WRNPLPNID PF15017.6 KFR00661.1 - 0.0022 18.9 0.2 0.0022 18.9 0.2 3.2 3 0 0 3 3 3 1 Putative WW-binding domain and destruction box Tash_PEST PF07708.11 KFR00661.1 - 6 7.2 8.9 0.24 11.6 1.3 2.8 3 0 0 3 3 3 0 Tash protein PEST motif fn3 PF00041.21 KFR00662.1 - 4.1e-78 257.8 0.2 4e-16 59.1 0.0 5.7 5 0 0 5 5 5 5 Fibronectin type III domain I-set PF07679.16 KFR00662.1 - 2.7e-74 245.3 13.5 4e-21 74.9 0.1 8.0 8 0 0 8 8 8 7 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR00662.1 - 2.2e-47 159.5 5.9 1.5e-10 41.5 0.1 7.4 7 0 0 7 7 7 6 Immunoglobulin domain Ig_2 PF13895.6 KFR00662.1 - 5.6e-36 122.7 4.5 1.1e-08 35.3 0.2 6.9 8 0 0 8 8 7 5 Immunoglobulin domain ig PF00047.25 KFR00662.1 - 7.5e-22 77.3 13.6 0.004 17.3 0.3 7.9 8 0 0 8 8 7 5 Immunoglobulin domain V-set PF07686.17 KFR00662.1 - 1.5e-15 57.3 22.7 0.076 13.2 1.7 10.1 7 4 1 8 8 8 5 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 KFR00662.1 - 1.1e-11 45.2 2.0 0.48 11.0 0.0 7.0 7 0 0 7 7 6 4 Purple acid Phosphatase, N-terminal domain C2-set_2 PF08205.12 KFR00662.1 - 9.7e-11 41.6 0.8 0.0051 16.9 0.0 4.4 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain Tissue_fac PF01108.17 KFR00662.1 - 0.00041 20.2 0.0 2 8.3 0.0 4.3 5 0 0 5 5 5 1 Tissue factor Interfer-bind PF09294.10 KFR00662.1 - 0.042 14.2 0.0 17 5.8 0.0 3.7 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III Invasin_D3 PF09134.10 KFR00662.1 - 0.065 13.5 4.1 21 5.5 0.2 4.8 5 0 0 5 5 5 0 Invasin, domain 3 EF-hand_7 PF13499.6 KFR00663.1 - 9.7e-14 51.6 6.1 1.1e-07 32.2 0.1 2.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KFR00663.1 - 1.2e-13 49.6 12.0 1.3e-07 30.7 1.6 4.5 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 KFR00663.1 - 1.8e-11 43.0 9.4 7.6e-08 31.7 0.9 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 KFR00663.1 - 3.7e-08 33.1 7.1 0.0025 17.6 0.5 3.7 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KFR00663.1 - 1.6e-05 24.2 4.2 1.8e-05 24.0 1.5 2.5 2 0 0 2 2 2 1 EF hand EF-hand_11 PF08976.11 KFR00663.1 - 2.1e-05 25.3 0.2 0.00077 20.3 0.1 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 KFR00663.1 - 0.0021 18.0 0.0 1.5 8.9 0.0 2.9 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0154) EF-hand_9 PF14658.6 KFR00663.1 - 0.0024 18.2 0.0 1.5 9.2 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain GPHH PF16905.5 KFR00663.1 - 0.015 15.0 0.0 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated SurA_N_2 PF13623.6 KFR00663.1 - 0.02 14.8 0.1 2.4 8.0 0.0 2.1 2 0 0 2 2 2 0 SurA N-terminal domain SPARC_Ca_bdg PF10591.9 KFR00663.1 - 0.024 14.9 0.9 0.043 14.1 0.4 1.6 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2267 PF10025.9 KFR00663.1 - 0.04 14.2 0.0 8.6 6.7 0.0 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2267) DUF2666 PF10869.8 KFR00663.1 - 0.095 12.9 0.0 0.43 10.8 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) DDE_Tnp_IS66_C PF13817.6 KFR00663.1 - 0.13 12.5 0.0 3.2 8.1 0.0 2.6 2 0 0 2 2 2 0 IS66 C-terminal element ADD_DNMT3 PF17980.1 KFR00688.1 - 4.4e-26 90.6 5.5 4.4e-26 90.6 5.5 2.2 2 0 0 2 2 2 1 Cysteine rich ADD domain in DNMT3 PWWP PF00855.17 KFR00688.1 - 1.7e-12 47.6 0.1 3.7e-12 46.5 0.1 1.6 1 0 0 1 1 1 1 PWWP domain DNA_methylase PF00145.17 KFR00688.1 - 7.3e-10 38.7 0.0 1.7e-05 24.4 0.0 3.3 3 0 0 3 3 3 3 C-5 cytosine-specific DNA methylase CCDC117 PF15810.5 KFR00690.1 - 1.2e-59 200.7 1.0 1.6e-59 200.3 1.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 117 Sugar_tr PF00083.24 KFR00691.1 - 1.9e-99 333.6 18.0 2.3e-99 333.3 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFR00691.1 - 1.1e-20 73.8 25.3 1.1e-20 73.8 25.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily C_GCAxxG_C_C PF09719.10 KFR00691.1 - 0.029 14.7 0.8 0.067 13.5 0.0 1.9 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) MFS_3 PF05977.13 KFR00691.1 - 0.28 9.5 5.1 0.17 10.3 0.3 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Romo1 PF10247.9 KFR00691.1 - 2.2 8.7 15.5 0.53 10.7 0.2 3.6 4 0 0 4 4 4 0 Reactive mitochondrial oxygen species modulator 1 Mpv17_PMP22 PF04117.12 KFR00691.1 - 8.2 6.7 9.1 10 6.5 0.2 2.9 3 0 0 3 3 3 0 Mpv17 / PMP22 family Pkinase PF00069.25 KFR00692.1 - 6.9e-75 251.8 0.0 8.9e-75 251.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR00692.1 - 1.3e-31 109.8 0.0 1.7e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KFR00692.1 - 9e-13 48.4 0.0 1.9e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KFR00692.1 - 3.5e-08 33.1 0.0 4.9e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFR00692.1 - 0.0033 16.3 0.3 0.01 14.6 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KFR00692.1 - 0.014 14.7 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KFR00692.1 - 0.065 12.8 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 KFR00692.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KFR00692.1 - 0.2 11.6 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family IP_trans PF02121.18 KFR00693.1 - 5.2e-109 363.6 2.3 5.8e-109 363.4 2.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Crystall PF00030.19 KFR00694.1 - 1.4e-53 179.0 5.3 3.2e-27 94.5 0.8 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall PF00030.19 KFR00695.1 - 3.3e-58 193.8 3.9 3.2e-29 101.0 0.4 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.13 KFR00695.1 - 4.4e-07 29.7 0.0 0.023 14.6 0.1 2.4 2 0 0 2 2 2 2 Peptidase inhibitor family I36 Crystall_3 PF08964.10 KFR00695.1 - 7.4e-06 26.0 0.2 0.062 13.5 0.0 2.5 2 1 0 2 2 2 2 Beta/Gamma crystallin IL4_i_Ig PF18258.1 KFR00695.1 - 0.0024 18.0 1.5 20 5.5 0.0 4.2 2 2 2 4 4 4 1 Interleukin-4 inducing immunoglobulin-binding domain Sulfotransfer_3 PF13469.6 KFR00696.1 - 2.1e-54 185.2 0.0 3.6e-54 184.4 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KFR00696.1 - 3.8e-07 29.8 0.1 3.1e-06 26.9 0.1 2.2 1 1 0 1 1 1 1 Sulfotransferase domain GCFC PF07842.12 KFR00697.1 - 1.3e-98 330.1 18.2 4.6e-98 328.2 15.7 2.2 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 KFR00697.1 - 1.3e-16 60.2 4.3 2.4e-16 59.4 4.3 1.5 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.8 KFR00697.1 - 2e-05 24.9 1.2 2e-05 24.9 1.2 2.2 3 0 0 3 3 3 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 KFR00697.1 - 0.00016 21.7 1.1 0.00048 20.2 1.1 1.8 1 0 0 1 1 1 1 G-patch domain Asp_Arg_Hydrox PF05118.15 KFR00700.1 - 1.4e-50 171.2 0.0 2.2e-50 170.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase UQ_con PF00179.26 KFR00700.1 - 0.17 11.5 0.0 0.39 10.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme Sushi PF00084.20 KFR00701.1 - 3.6e-39 133.2 19.0 8.6e-12 45.5 0.9 4.2 4 0 0 4 4 4 4 Sushi repeat (SCR repeat) CUB PF00431.20 KFR00701.1 - 1.5e-20 73.5 0.0 3.1e-19 69.4 0.0 2.6 2 1 0 2 2 2 1 CUB domain Amnionless PF14828.6 KFR00701.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Amnionless Fibrinogen_C PF00147.18 KFR00720.1 - 2.4e-65 220.4 0.0 3.7e-65 219.8 0.0 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Phage_lysis PF03245.13 KFR00720.1 - 0.0057 16.8 4.9 0.0057 16.8 4.9 1.9 1 1 0 1 1 1 1 Bacteriophage Rz lysis protein FAM110_N PF14161.6 KFR00721.1 - 5.2e-47 158.5 3.8 5.2e-47 158.5 3.8 1.7 2 0 0 2 2 2 1 Centrosome-associated N terminus FAM110_C PF14160.6 KFR00721.1 - 1.4e-33 116.3 0.0 2.3e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 Centrosome-associated C terminus DUF1011 PF06237.12 KFR00722.1 - 9.7e-41 138.1 9.3 9.7e-41 138.1 9.3 3.3 3 1 1 4 4 4 1 Protein of unknown function (DUF1011) DUF4131 PF13567.6 KFR00722.1 - 1.4 8.6 7.8 6.5 6.4 2.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Pacs-1 PF10254.9 KFR00723.1 - 9.9e-191 634.1 0.4 1.5e-190 633.6 0.0 1.5 2 0 0 2 2 2 1 PACS-1 cytosolic sorting protein hNIFK_binding PF12196.8 KFR00723.1 - 0.21 11.1 1.2 0.59 9.7 1.2 1.8 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK CECR6_TMEM121 PF14997.6 KFR00724.1 - 8.8e-62 208.4 12.3 8.8e-62 208.4 12.3 1.5 2 0 0 2 2 2 1 CECR6/TMEM121 family DUF5083 PF16890.5 KFR00724.1 - 0.004 16.9 1.7 0.004 16.9 1.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5083) RRP36 PF06102.12 KFR00725.1 - 1.3e-46 158.6 29.9 1.4e-46 158.5 29.9 1.0 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 SprA-related PF12118.8 KFR00725.1 - 2.9 6.9 9.7 3.6 6.6 9.7 1.2 1 0 0 1 1 1 0 SprA-related family Ureide_permease PF07168.11 KFR00725.1 - 7.7 5.2 6.4 9.6 4.8 6.4 1.1 1 0 0 1 1 1 0 Ureide permease Kelch_6 PF13964.6 KFR00726.1 - 5.3e-44 147.1 9.8 2.2e-09 37.3 0.1 6.3 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.15 KFR00726.1 - 8.5e-42 139.6 11.4 3.5e-07 29.9 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 KFR00726.1 - 1.4e-39 133.4 7.3 2.9e-08 33.1 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 KFR00726.1 - 1.8e-34 117.2 11.9 3.6e-06 26.8 0.3 6.5 6 1 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 KFR00726.1 - 5.6e-32 109.5 17.0 6.1e-08 32.6 0.2 7.5 5 3 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 KFR00726.1 - 6.7e-29 99.6 10.4 3.5e-06 27.2 0.2 7.2 7 0 0 7 7 7 5 Galactose oxidase, central domain MEA1 PF06910.11 KFR00727.1 - 7.6e-27 94.5 1.7 7.8e-27 94.4 1.7 1.0 1 0 0 1 1 1 1 Male enhanced antigen 1 (MEA1) B56 PF01603.20 KFR00728.1 - 3.2e-200 665.4 5.9 4.2e-200 665.0 5.9 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Stm1_N PF09598.10 KFR00728.1 - 0.079 13.8 5.6 0.24 12.3 5.6 1.8 1 0 0 1 1 1 0 Stm1 Hydrolase_4 PF12146.8 KFR00729.1 - 1.9e-17 63.3 0.0 7.3e-14 51.6 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFR00729.1 - 1.4e-15 57.6 0.4 1.9e-13 50.7 0.3 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFR00729.1 - 2e-09 38.4 0.8 6.1e-09 36.8 0.7 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KFR00729.1 - 0.00051 20.0 0.0 0.001 19.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KFR00729.1 - 0.0069 16.5 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.21 KFR00729.1 - 0.0092 15.5 0.0 0.046 13.2 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KFR00729.1 - 0.033 13.8 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 KFR00729.1 - 0.039 13.7 0.0 0.22 11.3 0.0 2.1 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Say1_Mug180 PF10340.9 KFR00729.1 - 0.092 11.6 0.0 0.21 10.4 0.0 1.6 1 1 0 1 1 1 0 Steryl acetyl hydrolase Chlorophyllase2 PF12740.7 KFR00729.1 - 0.1 11.5 0.0 0.77 8.6 0.0 1.9 1 1 0 1 1 1 0 Chlorophyllase enzyme LIP PF03583.14 KFR00729.1 - 0.22 10.8 0.0 0.48 9.7 0.0 1.5 2 0 0 2 2 2 0 Secretory lipase Phosphorylase PF00343.20 KFR00730.1 - 0 1148.9 0.0 0 1148.7 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase TPR_22 PF18833.1 KFR00730.1 - 0.00017 21.7 0.1 0.0004 20.5 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat GDA1_CD39 PF01150.17 KFR00731.1 - 1.2e-72 244.9 0.0 8.6e-72 242.1 0.0 2.0 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 KFR00731.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.4 1 1 0 1 1 1 0 Ppx/GppA phosphatase family Homeodomain PF00046.29 KFR00732.1 - 9.2e-24 83.1 2.6 1.8e-23 82.1 2.6 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFR00732.1 - 0.005 16.7 0.1 0.012 15.5 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Methyltransf_12 PF08242.12 KFR00733.1 - 0.0016 19.2 0.0 0.0028 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFR00733.1 - 0.0076 16.1 0.0 0.016 15.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFR00733.1 - 0.012 16.3 0.0 0.023 15.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KFR00733.1 - 0.021 14.7 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KFR00733.1 - 0.044 14.4 0.0 0.074 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF3456 PF11938.8 KFR00734.1 - 7.7e-29 101.2 0.2 8.5e-29 101.1 0.2 1.0 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP RNA_pol_Rpb2_6 PF00562.28 KFR00735.1 - 3.5e-115 385.2 0.0 1e-114 383.7 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KFR00735.1 - 5.8e-28 97.8 0.0 1.1e-27 96.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 KFR00735.1 - 5e-27 93.9 0.0 1.1e-26 92.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 KFR00735.1 - 8.6e-21 74.1 0.0 1.9e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.12 KFR00735.1 - 1.2e-18 66.8 0.0 2.4e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 KFR00735.1 - 2.9e-11 43.3 0.0 4.7e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 TTL PF03133.15 KFR00736.1 - 4.6e-68 229.5 0.1 1.3e-67 228.0 0.1 1.6 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KFR00736.1 - 2.2e-07 30.4 0.2 3.6e-06 26.4 0.0 2.4 2 1 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KFR00736.1 - 0.024 13.9 0.0 0.45 9.7 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp EntA_Immun PF08951.10 KFR00736.1 - 0.066 13.6 0.1 0.23 11.9 0.0 2.0 2 0 0 2 2 2 0 Enterocin A Immunity Sugar_tr PF00083.24 KFR00737.1 - 2e-32 112.6 20.6 2.6e-32 112.3 20.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFR00737.1 - 3.6e-29 101.8 27.0 4.7e-29 101.4 27.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KFR00737.1 - 0.079 11.4 10.2 0.0073 14.8 5.7 1.4 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KFR00737.1 - 0.39 10.0 23.1 0.57 9.4 11.6 2.2 2 0 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB Pkinase PF00069.25 KFR00738.1 - 4.3e-32 111.5 0.0 6.6e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR00738.1 - 1e-19 70.8 0.0 1.6e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFR00738.1 - 0.045 12.5 0.3 0.11 11.2 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase AMP-binding PF00501.28 KFR00739.1 - 5.9e-91 305.2 0.1 7e-91 304.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFR00739.1 - 2.4e-22 79.7 3.0 3.7e-22 79.1 0.8 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Str_synth PF03088.16 KFR00740.1 - 1.2e-25 89.5 0.1 6.7e-25 87.0 0.0 2.3 2 1 0 2 2 2 1 Strictosidine synthase SGL PF08450.12 KFR00740.1 - 1.6e-09 37.8 0.0 2.4e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KFR00740.1 - 4.3e-05 23.3 0.1 0.31 11.2 0.0 4.7 5 0 0 5 5 5 1 NHL repeat Arylesterase PF01731.20 KFR00740.1 - 0.0042 17.2 0.0 0.4 10.9 0.0 2.9 2 1 0 2 2 2 1 Arylesterase PQQ_3 PF13570.6 KFR00740.1 - 0.1 13.1 0.0 9.4 6.9 0.0 3.3 4 0 0 4 4 4 0 PQQ-like domain Cystatin PF00031.21 KFR00741.1 - 2.9e-15 56.3 0.0 3.4e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 KFR00741.1 - 0.00057 20.2 0.0 0.00085 19.6 0.0 1.3 1 0 0 1 1 1 1 Aspartic acid proteinase inhibitor N-glycanase_N PF09112.10 KFR00741.1 - 0.036 13.9 0.2 0.12 12.2 0.2 1.8 1 1 0 1 1 1 0 Peptide-N-glycosidase F, N terminal YmzC PF14157.6 KFR00741.1 - 0.044 13.9 0.0 0.08 13.0 0.0 1.5 2 0 0 2 2 2 0 YmzC-like protein Activin_recp PF01064.23 KFR00767.1 - 3.4 8.8 10.7 14 6.8 3.7 2.3 1 1 1 2 2 2 0 Activin types I and II receptor domain zf-H2C2_2 PF13465.6 KFR00768.1 - 2.3e-89 290.1 80.7 1.1e-09 38.3 0.3 13.1 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFR00768.1 - 1.1e-71 233.4 91.9 8.6e-07 29.1 0.4 12.1 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR00768.1 - 5e-44 145.1 86.9 0.00017 22.1 0.4 12.1 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFR00768.1 - 1.2e-23 82.8 38.0 0.074 13.4 0.3 12.3 12 0 0 12 12 12 9 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFR00768.1 - 9.5e-18 63.7 83.6 0.006 16.6 0.8 12.4 13 0 0 13 13 12 8 C2H2-type zinc finger zf-met PF12874.7 KFR00768.1 - 4.3e-15 55.5 71.6 0.071 13.5 0.7 11.8 12 0 0 12 12 12 7 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 KFR00768.1 - 1e-10 41.5 53.5 0.0014 18.7 0.8 8.0 2 2 8 10 10 10 8 Zinc ribbon domain zf_UBZ PF18439.1 KFR00768.1 - 7.9e-10 38.2 52.0 0.87 9.2 0.1 12.0 12 0 0 12 12 12 5 Ubiquitin-Binding Zinc Finger zf-AN1 PF01428.16 KFR00768.1 - 7.4e-09 35.6 66.8 0.091 12.9 1.2 12.0 11 1 1 12 12 12 3 AN1-like Zinc finger LIM PF00412.22 KFR00768.1 - 3.9e-08 33.4 61.5 0.4 11.0 2.0 10.4 3 3 6 9 9 9 7 LIM domain ADK_lid PF05191.14 KFR00768.1 - 1.4e-06 28.2 39.1 0.45 10.5 0.1 8.9 7 3 2 9 9 9 3 Adenylate kinase, active site lid zinc_ribbon_15 PF17032.5 KFR00768.1 - 2.3e-05 25.0 39.7 1 10.1 0.4 6.7 1 1 6 7 7 7 3 zinc-ribbon family FYDLN_acid PF09538.10 KFR00768.1 - 3.2e-05 24.5 29.8 0.69 10.6 0.1 10.5 1 1 11 12 12 12 1 Protein of unknown function (FYDLN_acid) zf_C2H2_ZHX PF18387.1 KFR00768.1 - 4e-05 23.2 59.5 0.62 9.7 0.1 11.2 2 2 10 12 12 12 7 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HE PF16278.5 KFR00768.1 - 0.00027 21.3 73.9 4.5 7.8 1.3 12.0 3 3 8 11 11 10 3 C2HE / C2H2 / C2HC zinc-binding finger zf-LYAR PF08790.11 KFR00768.1 - 0.00037 20.3 64.3 0.17 11.8 0.6 11.7 12 0 0 12 12 12 4 LYAR-type C2HC zinc finger HypA PF01155.19 KFR00768.1 - 0.00086 19.3 39.5 0.24 11.4 0.3 7.1 1 1 6 7 7 7 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_4 PF07975.12 KFR00768.1 - 0.0056 16.9 46.5 1.6 9.0 0.4 7.7 3 3 6 9 9 9 4 TFIIH C1-like domain zf-UBP PF02148.19 KFR00768.1 - 0.023 15.0 52.5 7.1 7.0 2.6 8.5 1 1 4 5 5 4 0 Zn-finger in ubiquitin-hydrolases and other protein YhfH PF14149.6 KFR00768.1 - 0.1 12.6 62.1 2.6 8.1 0.1 11.3 12 0 0 12 12 11 0 YhfH-like protein Siva PF05458.12 KFR00768.1 - 0.12 12.1 24.9 0.22 11.2 1.6 5.1 1 1 5 6 6 6 0 Cd27 binding protein (Siva) DUF3268 PF11672.8 KFR00768.1 - 0.15 12.4 30.0 1.6 9.1 1.1 6.2 2 1 6 9 9 9 0 zinc-finger-containing domain FAM178 PF14816.6 KFR00768.1 - 0.21 10.5 5.7 31 3.4 0.1 5.0 1 1 3 7 7 7 0 Family of unknown function, FAM178 BolA PF01722.18 KFR00768.1 - 0.22 11.8 0.1 0.22 11.8 0.1 5.3 2 2 3 5 5 5 0 BolA-like protein zf-trcl PF13451.6 KFR00768.1 - 1.7 8.6 57.5 5.1 7.1 0.2 11.7 12 0 0 12 12 12 0 Probable zinc-ribbon domain zf-C2H2_11 PF16622.5 KFR00768.1 - 1.8 8.4 64.2 0.14 11.9 0.6 11.1 11 0 0 11 11 11 0 zinc-finger C2H2-type CpXC PF14353.6 KFR00768.1 - 3.2 7.8 47.9 1.9 8.6 1.5 10.3 2 2 9 11 11 11 0 CpXC protein VWD PF00094.25 KFR00769.1 - 7.4e-06 26.3 0.1 1.2e-05 25.7 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type D domain VWD PF00094.25 KFR00770.1 - 8.1e-13 48.9 0.0 8.7e-13 48.8 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type D domain DUF5384 PF17358.2 KFR00771.1 - 0.3 11.1 10.5 0.12 12.4 1.8 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5384) zf-H2C2_2 PF13465.6 KFR00773.1 - 8.4e-77 250.4 74.3 7.7e-08 32.4 0.4 13.9 14 1 0 14 14 13 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFR00773.1 - 1.4e-74 242.6 81.2 1.4e-06 28.4 0.4 12.1 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR00773.1 - 2e-48 158.8 75.7 0.0015 19.2 1.0 12.1 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFR00773.1 - 2.8e-23 81.4 69.3 0.0035 17.3 0.1 12.4 12 0 0 12 12 12 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFR00773.1 - 1.7e-18 66.4 29.0 0.0024 18.1 0.0 11.8 12 0 0 12 12 12 4 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFR00773.1 - 1.7e-12 46.7 33.4 0.62 9.7 0.0 11.4 12 0 0 12 12 12 4 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFR00773.1 - 3.8e-12 46.1 46.3 0.051 13.7 0.3 9.7 7 4 2 10 10 9 6 Zinc ribbon domain zf-LYAR PF08790.11 KFR00773.1 - 1.9e-11 43.7 39.1 0.45 10.5 0.7 12.1 12 0 0 12 12 12 3 LYAR-type C2HC zinc finger CpXC PF14353.6 KFR00773.1 - 1.7e-08 34.5 38.2 3.2 7.8 0.1 11.3 6 4 2 10 10 10 1 CpXC protein zf-met PF12874.7 KFR00773.1 - 3.3e-08 33.6 55.2 0.035 14.5 0.1 11.8 12 0 0 12 12 12 3 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFR00773.1 - 1.3e-07 31.2 53.2 0.41 10.4 1.7 11.9 12 0 0 12 12 12 3 zinc-finger C2H2-type LIM PF00412.22 KFR00773.1 - 2.6e-07 30.8 45.7 0.3 11.4 1.0 9.9 6 5 1 8 8 8 2 LIM domain DZR PF12773.7 KFR00773.1 - 4.7e-07 29.7 45.7 0.07 13.2 3.4 6.8 2 2 2 4 4 3 3 Double zinc ribbon C1_4 PF07975.12 KFR00773.1 - 1.5e-06 28.4 31.5 0.46 10.8 2.1 7.7 4 2 3 8 8 8 4 TFIIH C1-like domain DUF3268 PF11672.8 KFR00773.1 - 5.3e-05 23.5 19.9 5.6 7.3 0.2 6.4 6 1 0 6 6 6 0 zinc-finger-containing domain DNA_RNApol_7kD PF03604.13 KFR00773.1 - 5.9e-05 22.7 35.8 3.2 7.5 0.1 10.7 11 0 0 11 11 11 1 DNA directed RNA polymerase, 7 kDa subunit YhfH PF14149.6 KFR00773.1 - 6.5e-05 22.8 37.0 11 6.0 0.0 11.0 12 0 0 12 12 11 0 YhfH-like protein zf-C2HE PF16278.5 KFR00773.1 - 0.00013 22.4 58.6 0.28 11.7 0.1 11.5 1 1 9 10 10 10 3 C2HE / C2H2 / C2HC zinc-binding finger HypA PF01155.19 KFR00773.1 - 0.00018 21.5 32.4 3 7.9 0.6 6.9 1 1 5 6 6 6 4 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_ZIC PF18366.1 KFR00773.1 - 0.00049 20.1 21.3 14 5.9 0.1 9.3 5 3 6 11 11 10 0 Zic proteins zinc finger domain zinc_ribbon_15 PF17032.5 KFR00773.1 - 0.00055 20.6 31.3 1.6 9.5 0.6 6.5 2 2 5 7 7 7 2 zinc-ribbon family C1_1 PF00130.22 KFR00773.1 - 0.0012 18.7 47.5 0.43 10.5 1.9 8.9 5 3 4 9 9 9 2 Phorbol esters/diacylglycerol binding domain (C1 domain) FYDLN_acid PF09538.10 KFR00773.1 - 0.0012 19.5 30.5 2.7 8.7 0.2 10.5 1 1 10 11 11 11 1 Protein of unknown function (FYDLN_acid) zf-AN1 PF01428.16 KFR00773.1 - 0.0023 18.0 55.4 5.5 7.2 0.2 12.0 12 0 0 12 12 12 1 AN1-like Zinc finger zf-Di19 PF05605.12 KFR00773.1 - 0.0034 17.7 43.1 0.16 12.3 0.5 8.1 3 2 6 10 10 10 4 Drought induced 19 protein (Di19), zinc-binding Prok-RING_1 PF14446.6 KFR00773.1 - 0.0054 16.6 28.9 22 5.0 0.0 10.4 12 0 0 12 12 11 0 Prokaryotic RING finger family 1 ADK_lid PF05191.14 KFR00773.1 - 0.037 14.0 37.1 6.1 6.9 0.1 8.4 6 3 1 7 7 7 0 Adenylate kinase, active site lid Zn_ribbon_recom PF13408.6 KFR00773.1 - 0.11 13.0 56.2 3.5 8.2 0.6 9.2 5 4 3 8 8 8 0 Recombinase zinc beta ribbon domain PhnA_Zn_Ribbon PF08274.12 KFR00773.1 - 0.32 11.0 0.0 0.32 11.0 0.0 4.2 5 0 0 5 5 3 0 PhnA Zinc-Ribbon TFIIS_C PF01096.18 KFR00773.1 - 0.37 10.7 47.4 13 5.7 0.1 11.3 12 0 0 12 12 12 0 Transcription factor S-II (TFIIS) zf_C2H2_ZHX PF18387.1 KFR00773.1 - 1 9.1 43.8 0.57 9.9 0.1 10.1 3 3 9 12 12 12 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-trcl PF13451.6 KFR00773.1 - 6.5 6.7 46.4 11 6.0 0.1 11.1 12 0 0 12 12 12 0 Probable zinc-ribbon domain zf-C2H2 PF00096.26 KFR00774.1 - 2e-30 103.5 68.2 5.8e-05 23.3 0.8 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFR00774.1 - 4.2e-28 96.5 55.1 6.9e-07 29.4 4.0 8.9 9 1 0 9 9 9 7 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR00774.1 - 2.5e-23 80.7 62.0 0.00043 20.9 3.6 8.1 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFR00774.1 - 3.3e-05 23.5 53.4 0.00023 20.9 0.8 7.4 8 0 0 8 8 8 2 zinc-finger C2H2-type BolA PF01722.18 KFR00774.1 - 0.00032 20.9 1.9 13 6.1 0.0 4.5 3 2 1 4 4 4 1 BolA-like protein zf-met PF12874.7 KFR00774.1 - 0.0072 16.7 52.2 0.026 14.9 3.8 6.5 8 0 0 8 8 8 4 Zinc-finger of C2H2 type Fer4_8 PF13183.6 KFR00774.1 - 0.031 14.7 2.7 0.031 14.7 2.7 4.8 3 2 0 3 3 2 0 4Fe-4S dicluster domain DNA_RNApol_7kD PF03604.13 KFR00774.1 - 0.14 11.8 0.0 0.14 11.8 0.0 6.9 7 0 0 7 7 7 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_jaz PF12171.8 KFR00774.1 - 0.26 11.6 48.9 0.5 10.7 4.0 7.7 8 0 0 8 8 8 0 Zinc-finger double-stranded RNA-binding CpXC PF14353.6 KFR00774.1 - 0.27 11.3 0.0 0.27 11.3 0.0 6.1 3 2 3 7 7 7 0 CpXC protein zinc_ribbon_15 PF17032.5 KFR00774.1 - 0.6 10.9 27.8 2.4 9.0 1.2 4.0 2 1 2 4 4 4 0 zinc-ribbon family C1_4 PF07975.12 KFR00774.1 - 5.7 7.3 39.1 0.09 13.0 1.6 5.7 1 1 4 5 5 5 0 TFIIH C1-like domain KRAB PF01352.27 KFR00775.1 - 4.8e-12 45.3 1.2 1e-11 44.3 0.1 2.0 2 0 0 2 2 2 1 KRAB box DUF3669 PF12417.8 KFR00775.1 - 3e-07 30.5 0.0 5.9e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Zinc finger protein DASH_Hsk3 PF08227.11 KFR00775.1 - 0.35 11.3 1.8 0.68 10.3 0.7 2.0 1 1 1 2 2 2 0 DASH complex subunit Hsk3 like zf-C2H2 PF00096.26 KFR00776.1 - 1.7e-13 50.2 12.3 2.8e-07 30.6 2.4 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFR00776.1 - 3.3e-10 39.9 0.5 3.3e-10 39.9 0.5 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR00776.1 - 1.4e-09 38.0 10.7 0.00016 22.3 2.1 2.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFR00776.1 - 0.00017 21.9 7.4 0.089 13.2 1.4 2.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFR00776.1 - 0.00019 21.6 3.8 0.036 14.4 0.1 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFR00776.1 - 0.0017 18.2 0.4 0.0017 18.2 0.4 2.2 3 0 0 3 3 3 1 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 KFR00776.1 - 0.0082 16.2 0.8 0.067 13.3 0.7 2.0 1 1 1 2 2 2 2 Zinc ribbon domain zf-C2H2_8 PF15909.5 KFR00776.1 - 0.0094 16.2 2.4 0.0099 16.2 2.4 1.0 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 KFR00776.1 - 0.015 15.1 16.3 0.051 13.3 2.3 3.6 2 2 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFR00776.1 - 0.015 15.3 9.9 0.19 11.8 0.6 2.7 2 2 0 2 2 2 0 C2H2-type zinc finger LIM PF00412.22 KFR00776.1 - 0.03 14.5 1.9 0.068 13.4 1.9 1.6 1 1 0 1 1 1 0 LIM domain zf-C2H2_11 PF16622.5 KFR00776.1 - 0.032 14.0 7.5 1.2 8.9 2.4 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type DZR PF12773.7 KFR00776.1 - 0.035 14.1 1.0 0.045 13.8 1.0 1.2 1 0 0 1 1 1 0 Double zinc ribbon Arc_trans_TRASH PF08394.10 KFR00776.1 - 0.039 14.3 0.9 0.26 11.7 0.9 2.0 1 1 0 1 1 1 0 Archaeal TRASH domain zf-C2H2_7 PF15269.6 KFR00776.1 - 0.058 13.5 1.4 0.058 13.5 1.4 1.6 1 1 1 2 2 2 0 Zinc-finger zf-C4_ClpX PF06689.13 KFR00776.1 - 0.064 13.2 0.5 0.39 10.6 0.5 2.0 1 1 0 1 1 1 0 ClpX C4-type zinc finger zf-BED PF02892.15 KFR00776.1 - 0.076 13.1 4.0 0.17 11.9 0.4 2.2 1 1 1 2 2 2 0 BED zinc finger PyrI_C PF02748.15 KFR00776.1 - 0.079 12.9 1.6 1.7 8.6 0.0 2.1 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn_ribbon_recom PF13408.6 KFR00776.1 - 0.1 13.1 1.1 0.16 12.5 1.1 1.4 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain zf_UBZ PF18439.1 KFR00776.1 - 0.12 12.0 3.8 5.5 6.7 0.8 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn_Tnp_IS1595 PF12760.7 KFR00776.1 - 0.18 11.8 4.8 0.29 11.1 4.8 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-LYAR PF08790.11 KFR00776.1 - 0.2 11.6 2.8 6.9 6.7 0.2 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-AN1 PF01428.16 KFR00776.1 - 0.43 10.8 5.5 2.4 8.4 0.5 2.3 2 0 0 2 2 2 0 AN1-like Zinc finger zf-C2HE PF16278.5 KFR00776.1 - 3 8.4 8.1 12 6.4 3.9 2.4 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger PC4 PF02229.16 KFR00780.1 - 0.023 14.3 0.5 0.046 13.4 0.1 1.8 2 1 0 2 2 2 0 Transcriptional Coactivator p15 (PC4) QLQ PF08880.11 KFR00780.1 - 0.025 14.3 0.2 0.036 13.8 0.2 1.2 1 0 0 1 1 1 0 QLQ RGS12_us1 PF16613.5 KFR00780.1 - 0.032 14.5 7.9 0.044 14.1 7.9 1.3 1 0 0 1 1 1 0 Unstructured region of RGS12 SERTA PF06031.13 KFR00800.1 - 5.6e-18 64.3 2.2 1.2e-17 63.2 2.2 1.6 1 0 0 1 1 1 1 SERTA motif DUF4279 PF14106.6 KFR00800.1 - 0.03 14.5 0.1 0.071 13.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) GET2 PF08690.10 KFR00800.1 - 0.17 11.6 6.0 0.22 11.1 6.0 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 DUF4521 PF15021.6 KFR00800.1 - 0.27 11.1 6.3 0.19 11.6 2.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4521) Clathrin_bdg PF15045.6 KFR00801.1 - 2.2e-34 117.3 0.3 7.6e-34 115.6 0.3 2.0 1 0 0 1 1 1 1 Clathrin-binding box of Aftiphilin, vesicle trafficking E2R135 PF11570.8 KFR00801.1 - 0.039 14.2 0.0 0.085 13.2 0.0 1.6 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 PDZ PF00595.24 KFR00802.1 - 9.6e-06 25.9 0.0 1.8e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFR00802.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 PDZ domain LRR_6 PF13516.6 KFR00803.1 - 1.6e-15 55.7 17.9 0.0016 18.3 0.2 8.3 9 0 0 9 9 9 5 Leucine Rich repeat LRR_8 PF13855.6 KFR00803.1 - 2.8e-05 23.8 15.9 0.007 16.1 0.4 5.5 4 2 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 KFR00803.1 - 3.1e-05 24.2 22.6 0.068 13.6 0.8 6.2 4 2 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFR00803.1 - 0.0027 18.0 18.7 1.2 10.0 0.3 7.2 8 1 0 8 8 8 2 Leucine Rich Repeat 3HCDH_RFF PF18321.1 KFR00803.1 - 0.17 12.4 0.0 1.1 9.7 0.0 2.4 2 1 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain RP-C_C PF11800.8 KFR00803.1 - 0.18 11.9 3.6 0.37 10.8 3.6 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region DIL PF01843.19 KFR00803.1 - 0.28 11.5 1.8 1.1 9.6 0.3 2.4 2 0 0 2 2 2 0 DIL domain GCN5L1 PF06320.13 KFR00817.1 - 1.3e-33 115.5 2.1 1.4e-33 115.4 2.1 1.0 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) MCPsignal PF00015.21 KFR00817.1 - 0.025 14.4 0.1 0.032 14.0 0.1 1.1 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Seryl_tRNA_N PF02403.22 KFR00817.1 - 0.042 14.1 0.1 0.045 14.0 0.1 1.0 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain SAND PF01342.21 KFR00817.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 SAND domain ELL PF10390.9 KFR00818.1 - 1.2e-92 310.3 0.3 1.2e-92 310.3 0.3 2.0 2 0 0 2 2 2 1 RNA polymerase II elongation factor ELL Occludin_ELL PF07303.13 KFR00818.1 - 9.4e-31 106.5 9.5 9.4e-31 106.5 9.5 3.0 3 1 0 3 3 3 1 Occludin homology domain RXT2_N PF08595.11 KFR00818.1 - 0.14 12.2 6.8 0.08 13.0 3.5 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Peptidase_S8 PF00082.22 KFR00819.1 - 5.7e-36 124.3 3.7 6.9e-36 124.0 2.8 1.6 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.20 KFR00819.1 - 2.8e-30 104.2 0.5 5.4e-30 103.3 0.5 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Proho_convert PF12177.8 KFR00819.1 - 8.7e-22 76.8 2.5 8.7e-22 76.8 2.5 2.7 3 0 0 3 3 3 1 Prohormone convertase enzyme S8_pro-domain PF16470.5 KFR00819.1 - 2.6e-11 44.1 4.1 2.6e-11 44.1 4.1 2.3 2 0 0 2 2 2 1 Peptidase S8 pro-domain Peptidase_S8_N PF16361.5 KFR00819.1 - 0.0026 18.3 0.9 0.0098 16.4 0.9 2.0 1 0 0 1 1 1 1 N-terminal of Subtilase family Calpain_inhib PF00748.19 KFR00820.1 - 1.3e-128 424.0 115.8 8.1e-39 133.2 18.9 6.5 5 1 1 6 6 6 5 Calpain inhibitor Peptidase_M1 PF01433.20 KFR00821.1 - 1.2e-82 276.7 0.7 3.1e-82 275.4 0.3 1.9 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 KFR00821.1 - 2.2e-73 247.5 0.7 3.2e-73 247.0 0.7 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KFR00821.1 - 1.4e-24 87.3 0.4 3e-24 86.2 0.1 1.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain SesA PF17107.5 KFR00821.1 - 0.13 12.5 0.2 0.55 10.4 0.1 2.1 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases ApoC-I PF04691.12 KFR00821.1 - 9 6.3 7.8 1.3 9.0 0.7 3.0 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) FAM27 PF15832.5 KFR00862.1 - 6.5 7.4 13.8 2.4 8.7 5.7 3.5 3 0 0 3 3 3 0 FAM27 D and E protein family LMBR1 PF04791.16 KFR00862.1 - 7.5 5.3 5.0 17 4.2 5.0 1.6 1 0 0 1 1 1 0 LMBR1-like membrane protein MyTH4 PF00784.17 KFR00863.1 - 7.4e-32 110.1 1.4 7.9e-29 100.3 0.2 3.3 2 1 0 2 2 2 1 MyTH4 domain RhoGAP PF00620.27 KFR00863.1 - 8.9e-32 110.0 0.0 2.2e-31 108.7 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain WW PF00397.26 KFR00863.1 - 1.4e-05 25.0 7.2 4.9e-05 23.3 7.2 2.1 1 0 0 1 1 1 1 WW domain DUF4505 PF14956.6 KFR00864.1 - 5.2e-55 185.9 0.0 5.7e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4505) LRR_6 PF13516.6 KFR00865.1 - 1.8e-05 24.4 0.3 6.9 7.0 0.1 4.8 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.7 KFR00865.1 - 0.02 15.3 5.6 5.1 7.7 0.7 4.2 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) 7tm_4 PF13853.6 KFR00866.1 - 0.011 15.4 0.2 0.013 15.2 0.2 1.1 1 0 0 1 1 1 0 Olfactory receptor 7tm_4 PF13853.6 KFR00867.1 - 1.1e-36 127.1 10.7 1.2e-36 126.9 10.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFR00867.1 - 3.5e-25 88.8 15.3 1.1e-24 87.2 15.3 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pep_M12B_propep PF01562.19 KFR00914.1 - 2.9e-32 111.8 0.0 6.3e-32 110.7 0.0 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_spacer1 PF05986.14 KFR00914.1 - 4.6e-32 110.4 0.0 8.2e-32 109.6 0.0 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.19 KFR00914.1 - 1.5e-22 79.6 56.4 2.1e-10 40.7 5.4 6.3 6 0 0 6 6 6 4 Thrombospondin type 1 domain ADAM_CR_2 PF17771.1 KFR00914.1 - 5.2e-21 75.0 19.5 5.5e-20 71.6 7.0 5.4 5 1 1 6 6 3 2 ADAM cysteine-rich domain Reprolysin PF01421.19 KFR00914.1 - 2.3e-19 70.1 0.0 4.7e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 KFR00914.1 - 1.5e-13 51.4 0.6 3.5e-13 50.1 0.6 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KFR00914.1 - 1.3e-09 38.3 0.3 2.5e-09 37.3 0.3 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 KFR00914.1 - 1.3e-09 38.6 0.3 2.5e-09 37.7 0.3 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFR00914.1 - 1.5e-06 28.0 0.2 3.3e-06 26.9 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like PLAC PF08686.11 KFR00914.1 - 6.2e-05 23.7 5.6 0.00042 21.0 5.6 2.7 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Peptidase_M10 PF00413.24 KFR00914.1 - 0.0011 18.8 0.1 0.0024 17.7 0.1 1.6 1 0 0 1 1 1 1 Matrixin DUF4953 PF16313.5 KFR00914.1 - 0.1 11.8 0.4 0.17 11.0 0.4 1.2 1 0 0 1 1 1 0 Met-zincin 60KD_IMP PF02096.20 KFR00915.1 - 4.6e-15 55.9 0.0 7.3e-15 55.3 0.0 1.3 1 1 0 1 1 1 1 60Kd inner membrane protein HlyC PF02794.16 KFR00915.1 - 0.011 15.6 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 RTX toxin acyltransferase family Serum_albumin PF00273.20 KFR00916.1 - 2.1e-152 503.1 33.7 6.9e-56 188.8 9.8 3.1 3 0 0 3 3 3 3 Serum albumin family VitD-bind_III PF09164.10 KFR00916.1 - 4.9e-07 29.6 8.9 0.1 12.6 0.0 6.0 5 0 0 5 5 5 4 Vitamin D binding protein, domain III CYTL1 PF15153.6 KFR00916.1 - 0.002 18.1 3.6 0.0078 16.2 0.1 3.1 3 0 0 3 3 3 1 Cytokine-like protein 1 Serum_albumin PF00273.20 KFR00917.1 - 1.6e-150 497.0 39.5 2.7e-57 193.4 12.4 3.1 3 0 0 3 3 3 3 Serum albumin family VitD-bind_III PF09164.10 KFR00917.1 - 9.8e-07 28.7 14.6 0.001 19.0 0.8 4.9 4 0 0 4 4 4 3 Vitamin D binding protein, domain III RA PF00788.23 KFR00918.1 - 9.9e-12 45.3 0.0 2.3e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Nore1-SARAH PF16517.5 KFR00918.1 - 4.2e-11 42.6 5.1 4.2e-11 42.6 5.1 2.2 2 0 0 2 2 2 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Ras_bdg_2 PF14847.6 KFR00918.1 - 0.011 16.0 0.5 0.05 13.9 0.2 2.3 2 1 0 2 2 2 0 Ras-binding domain of Byr2 RecO_C PF02565.15 KFR00918.1 - 0.075 12.8 0.1 0.41 10.4 0.0 2.1 1 1 1 2 2 2 0 Recombination protein O C terminal YusW PF14039.6 KFR00918.1 - 0.093 13.3 1.1 0.53 10.8 0.0 2.6 3 0 0 3 3 3 0 YusW-like protein TUG-UBL1 PF11470.8 KFR00918.1 - 0.14 12.4 0.2 0.38 11.0 0.0 1.8 2 0 0 2 2 2 0 TUG ubiquitin-like domain IL8 PF00048.20 KFR00919.1 - 1.1e-16 60.7 0.3 1.4e-16 60.4 0.3 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like IL8 PF00048.20 KFR00920.1 - 1.9e-17 63.2 0.8 2.2e-17 62.9 0.8 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like THF_DHG_CYH_C PF02882.19 KFR00921.1 - 3e-61 205.4 4.5 4.3e-61 204.9 4.5 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KFR00921.1 - 1.4e-37 128.5 0.2 2e-37 128.0 0.2 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain EGF PF00008.27 KFR00922.1 - 0.042 14.2 3.4 0.086 13.2 3.4 1.6 1 0 0 1 1 1 0 EGF-like domain DUF4514 PF14986.6 KFR00922.1 - 0.13 12.2 0.5 0.24 11.4 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) SKG6 PF08693.10 KFR00922.1 - 0.74 9.3 5.0 1.7 8.1 5.0 1.6 1 1 0 1 1 1 0 Transmembrane alpha-helix domain EGF PF00008.27 KFR00923.1 - 8.9e-05 22.7 3.4 0.00017 21.8 3.4 1.5 1 0 0 1 1 1 1 EGF-like domain TMEM52 PF14979.6 KFR00923.1 - 0.005 16.8 0.3 0.0069 16.3 0.3 1.2 1 0 0 1 1 1 1 Transmembrane 52 Comm PF15957.5 KFR00923.1 - 0.063 13.6 0.1 0.099 13.0 0.1 1.3 1 0 0 1 1 1 0 Commissureless EphA2_TM PF14575.6 KFR00923.1 - 0.13 13.1 0.5 0.22 12.4 0.5 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain EGF_2 PF07974.13 KFR00923.1 - 1.5 9.2 7.1 0.4 11.1 3.2 2.1 2 1 0 2 2 2 0 EGF-like domain Ycf70 PF17382.2 KFR00924.1 - 0.001 19.4 1.0 0.0071 16.7 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized Ycf70-like EGF PF00008.27 KFR00924.1 - 0.0012 19.1 3.2 0.002 18.4 3.2 1.4 1 0 0 1 1 1 1 EGF-like domain PRIMA1 PF16101.5 KFR00924.1 - 0.02 14.9 0.1 0.043 13.9 0.1 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 FtsL PF04999.13 KFR00924.1 - 0.029 14.3 0.2 0.047 13.7 0.2 1.3 1 0 0 1 1 1 0 Cell division protein FtsL DUF3377 PF11857.8 KFR00924.1 - 0.035 14.0 0.3 0.079 12.9 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) ECSCR PF15820.5 KFR00924.1 - 0.041 13.7 0.4 0.041 13.7 0.4 1.9 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator TMEM154 PF15102.6 KFR00924.1 - 0.47 10.3 4.9 0.1 12.5 0.9 1.7 1 1 0 2 2 2 0 TMEM154 protein family Protocadherin PF08374.11 KFR00924.1 - 1.2 9.0 5.4 0.77 9.7 0.1 2.1 2 0 0 2 2 2 0 Protocadherin EphA2_TM PF14575.6 KFR00924.1 - 3.8 8.4 5.3 0.67 10.9 0.2 2.1 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Uso1_p115_head PF04869.14 KFR00925.1 - 8.3e-62 209.1 0.0 8.3e-62 209.1 0.0 2.5 3 0 0 3 3 3 1 Uso1 / p115 like vesicle tethering protein, head region Arm_vescicular PF18770.1 KFR00925.1 - 4.4e-29 100.2 1.0 4.4e-29 100.2 1.0 2.7 2 0 0 2 2 2 1 Armadillo tether-repeat of vescicular transport factor Uso1_p115_C PF04871.13 KFR00925.1 - 4.3e-10 40.1 31.5 4.3e-10 40.1 31.5 4.1 2 1 2 4 4 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region Leu_zip PF15294.6 KFR00925.1 - 0.0034 17.0 5.6 0.0034 17.0 5.6 4.0 2 1 0 3 3 3 1 Leucine zipper TMF_TATA_bd PF12325.8 KFR00925.1 - 0.0042 17.3 12.7 0.0042 17.3 12.7 5.2 2 1 0 4 4 4 1 TATA element modulatory factor 1 TATA binding TACC_C PF05010.14 KFR00925.1 - 0.008 16.0 23.0 0.008 16.0 23.0 3.4 3 1 0 3 3 3 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF4407 PF14362.6 KFR00925.1 - 0.01 15.2 26.6 0.018 14.4 7.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Nnf1 PF03980.14 KFR00925.1 - 0.014 15.7 4.5 0.014 15.7 4.5 4.7 3 1 0 4 4 4 0 Nnf1 Mod_r PF07200.13 KFR00925.1 - 0.044 13.9 51.3 0.086 13.0 7.0 4.2 4 0 0 4 4 4 0 Modifier of rudimentary (Mod(r)) protein DUF3800 PF12686.7 KFR00925.1 - 0.098 13.3 0.0 14 6.3 0.0 3.6 2 2 0 2 2 2 0 Protein of unknown function (DUF3800) KASH_CCD PF14662.6 KFR00925.1 - 0.23 11.3 49.4 0.11 12.3 28.0 3.3 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH Surfac_D-trimer PF09006.11 KFR00925.1 - 0.37 10.7 1.9 23 5.0 0.9 3.6 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation ADIP PF11559.8 KFR00925.1 - 0.64 10.1 52.1 0.46 10.6 4.7 5.2 4 1 0 5 5 5 0 Afadin- and alpha -actinin-Binding DUF2937 PF11157.8 KFR00925.1 - 2.6 7.7 5.5 11 5.6 2.6 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) SHE3 PF17078.5 KFR00925.1 - 4 7.1 49.7 0.3 10.8 7.5 3.0 3 0 0 3 3 3 0 SWI5-dependent HO expression protein 3 VPS11_C PF12451.8 KFR00925.1 - 6.7 7.0 14.6 0.079 13.2 0.6 4.4 3 1 1 4 4 4 0 Vacuolar protein sorting protein 11 C terminal NTF2 PF02136.20 KFR00926.1 - 3e-33 114.9 0.1 5.1e-33 114.2 0.1 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KFR00926.1 - 4.1e-14 52.2 0.1 8.5e-14 51.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFR00926.1 - 8.6e-06 25.8 0.0 2.1e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif Pkinase PF00069.25 KFR00927.1 - 1.7e-42 145.6 0.8 4.2e-42 144.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR00927.1 - 1.7e-24 86.5 0.0 4e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR00927.1 - 2.4e-08 33.7 1.7 2.2e-07 30.5 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFR00927.1 - 0.0011 17.9 1.0 0.0069 15.2 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 KFR00927.1 - 0.0065 15.5 0.1 0.0065 15.5 0.1 2.1 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KFR00927.1 - 0.03 14.2 0.1 0.03 14.2 0.1 3.1 2 2 1 3 3 3 0 Phosphotransferase enzyme family Med15 PF09606.10 KFR00927.1 - 4.6 5.8 40.4 6.7 5.3 40.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BMP2K_C PF15282.6 KFR00928.1 - 6.2e-122 406.4 17.0 6e-121 403.2 12.1 2.2 2 0 0 2 2 2 2 BMP-2-inducible protein kinase C-terminus DivIC PF04977.15 KFR00928.1 - 0.017 14.8 0.8 0.05 13.4 0.8 1.8 1 0 0 1 1 1 0 Septum formation initiator HpuA PF16960.5 KFR00928.1 - 0.064 12.4 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 Haemoglobin-haptoglobin utilisation, porphyrin transporter HlyIII PF03006.20 KFR00929.1 - 9.4e-49 166.1 24.6 1.2e-48 165.8 24.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related Presenilin PF01080.17 KFR00929.1 - 3.6 6.2 12.0 6.6 5.4 0.0 2.4 2 1 0 2 2 2 0 Presenilin DUF2070 PF09843.9 KFR00929.1 - 5.1 5.3 11.1 6.6 4.9 11.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ant_C PF05586.11 KFR00930.1 - 2.1e-41 140.4 0.5 2.1e-41 140.4 0.5 1.8 2 0 0 2 2 2 1 Anthrax receptor C-terminus region VWA PF00092.28 KFR00931.1 - 7.2e-11 42.6 0.1 8.1e-11 42.5 0.1 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFR00931.1 - 0.001 19.7 0.1 0.004 17.8 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain LpxI_N PF17930.1 KFR00931.1 - 0.09 12.7 0.0 0.14 12.1 0.0 1.4 1 1 0 1 1 1 0 LpxI N-terminal domain FGF PF00167.18 KFR00932.1 - 8.8e-32 109.8 0.1 9.6e-32 109.7 0.1 1.0 1 0 0 1 1 1 1 Fibroblast growth factor TGF_beta PF00019.20 KFR00933.1 - 2e-30 105.8 0.5 2e-30 105.8 0.5 2.2 3 0 0 3 3 3 1 Transforming growth factor beta like domain ATP-synt_ab PF00006.25 KFR00938.1 - 8.2e-75 251.1 0.0 1.3e-74 250.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KFR00938.1 - 2.6e-47 160.3 2.3 4e-47 159.7 2.3 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain DUF4142 PF13628.6 KFR00938.1 - 0.00012 22.3 2.7 0.00021 21.6 2.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4142) ATPase PF06745.13 KFR00938.1 - 0.05 12.9 0.1 0.14 11.5 0.1 1.7 2 0 0 2 2 2 0 KaiC Yae1_N PF09811.9 KFR00941.1 - 6.5e-10 38.5 28.4 5.5 6.8 28.4 3.1 1 1 0 1 1 1 1 Essential protein Yae1, N terminal LRR_8 PF13855.6 KFR00943.1 - 3.1e-50 167.8 49.9 3.3e-12 46.0 5.2 6.9 2 2 5 7 7 7 7 Leucine rich repeat LRR_5 PF13306.6 KFR00943.1 - 2.2e-15 56.7 0.0 7.1e-07 29.2 0.1 2.5 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFR00943.1 - 3.3e-14 52.8 44.7 0.011 16.2 2.5 9.1 3 2 7 11 11 11 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFR00943.1 - 6e-07 29.1 15.8 0.009 15.5 0.4 4.3 2 2 2 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 KFR00943.1 - 3.9e-05 23.6 31.4 8 7.5 0.7 10.6 11 1 0 11 11 11 2 Leucine Rich Repeat LRRNT PF01462.18 KFR00943.1 - 0.78 9.5 17.0 0.037 13.7 3.1 3.1 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain DUF4462 PF14692.6 KFR00945.1 - 0.61 9.6 1.8 1.7 8.2 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) LRR_8 PF13855.6 KFR00946.1 - 1.4e-46 156.1 40.8 1.6e-14 53.4 6.4 6.5 2 2 4 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 KFR00946.1 - 2.4e-19 69.1 43.9 2.5e-06 27.7 0.6 7.3 6 1 3 9 9 9 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFR00946.1 - 2e-17 63.3 0.0 3.3e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFR00946.1 - 1.4e-07 31.2 20.3 0.019 14.4 0.9 5.1 2 2 3 5 5 5 3 Leucine-rich repeat LRR_1 PF00560.33 KFR00946.1 - 0.00068 19.8 39.5 1.1 10.1 0.2 11.9 12 1 0 12 12 12 1 Leucine Rich Repeat TMEM154 PF15102.6 KFR00946.1 - 0.0081 16.1 0.3 0.027 14.4 0.1 1.8 1 1 1 2 2 2 1 TMEM154 protein family EphA2_TM PF14575.6 KFR00946.1 - 0.03 15.2 0.0 0.066 14.1 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Neur_chan_memb PF02932.16 KFR00946.1 - 0.033 14.2 0.6 0.054 13.6 0.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CcmD PF04995.14 KFR00946.1 - 0.71 10.0 2.5 2.3 8.4 0.4 2.5 2 1 0 2 2 2 0 Heme exporter protein D (CcmD) LRRNT PF01462.18 KFR00946.1 - 0.72 9.6 9.5 0.19 11.4 2.5 3.1 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Peptidase_A17 PF05380.13 KFR00948.1 - 0.33 10.9 1.9 0.51 10.3 0.1 1.9 1 1 1 2 2 2 0 Pao retrotransposon peptidase C2 PF00168.30 KFR00968.1 - 7.6e-12 45.4 0.0 1.1e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 C2 domain PH_6 PF15406.6 KFR00968.1 - 0.064 13.5 0.1 0.24 11.7 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain Glyco_hydro_31 PF01055.26 KFR00969.1 - 2.3e-11 43.6 0.1 3.7e-11 42.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 SMRP1 PF15181.6 KFR00971.1 - 6e-68 229.3 13.2 3.7e-67 226.7 13.2 1.8 1 1 0 1 1 1 1 Spermatid-specific manchette-related protein 1 7tm_4 PF13853.6 KFR00974.1 - 1.2e-34 120.3 20.5 1.6e-34 119.9 20.5 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFR00974.1 - 1.5e-15 57.3 23.3 3.4e-15 56.1 23.3 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FH2 PF02181.23 KFR00984.1 - 2.2e-98 329.8 6.1 2.2e-98 329.8 6.1 1.6 2 0 0 2 2 2 1 Formin Homology 2 Domain DUF1043 PF06295.12 KFR00984.1 - 0.74 9.8 7.9 1.4 8.9 3.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF883 PF05957.13 KFR00984.1 - 5.7 7.6 7.7 3.3 8.4 2.3 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DAN PF03045.15 KFR00985.1 - 7.5e-39 132.3 9.7 1.1e-38 131.7 9.7 1.2 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.22 KFR00985.1 - 3.3e-05 24.1 7.4 4.4e-05 23.7 7.4 1.2 1 0 0 1 1 1 1 Cystine-knot domain zf-C2HCIx2C PF10782.9 KFR00985.1 - 1.9 8.5 8.5 3.1 7.8 2.3 2.3 1 1 1 2 2 2 0 Zinc-finger Secretogranin_V PF05281.11 KFR00986.1 - 5.4e-13 49.1 0.6 4e-10 39.7 0.1 2.1 1 1 1 2 2 2 2 Neuroendocrine protein 7B2 precursor (Secretogranin V) RhoGAP PF00620.27 KFR00987.1 - 2.3e-31 108.7 0.2 6.1e-31 107.3 0.2 1.8 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.19 KFR00988.1 - 1.1e-44 152.7 0.2 2.6e-44 151.5 0.2 1.6 1 0 0 1 1 1 1 RasGEF domain C1_1 PF00130.22 KFR00988.1 - 3e-15 55.8 7.9 7.1e-15 54.6 7.9 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_7 PF13499.6 KFR00988.1 - 9.7e-07 29.2 3.5 0.00092 19.6 0.4 3.5 3 2 2 5 5 5 2 EF-hand domain pair EF-hand_6 PF13405.6 KFR00988.1 - 8.6e-06 25.3 0.1 5.3e-05 22.8 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KFR00988.1 - 2.8e-05 23.3 3.0 3.9e-05 22.9 0.2 2.9 3 0 0 3 3 3 1 EF hand RasGEF_N PF00618.20 KFR00988.1 - 0.0001 22.5 3.7 0.00012 22.3 1.3 2.4 2 0 0 2 2 2 1 RasGEF N-terminal motif EF-hand_5 PF13202.6 KFR00988.1 - 0.00012 21.4 2.4 0.00032 20.0 0.1 2.8 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 KFR00988.1 - 0.01 15.7 0.2 0.051 13.4 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain pair bZIP_1 PF00170.21 KFR00988.1 - 0.024 14.7 1.2 0.12 12.5 1.2 2.2 1 0 0 1 1 1 0 bZIP transcription factor UvrD_C PF13361.6 KFR00988.1 - 0.062 12.7 0.6 0.11 11.8 0.6 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ACDC PF14733.6 KFR00988.1 - 0.081 13.3 0.8 0.33 11.3 0.2 2.3 2 0 0 2 2 2 0 AP2-coincident C-terminal GAS PF13851.6 KFR00988.1 - 0.093 12.1 5.3 0.19 11.1 5.3 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Sprouty PF05210.13 KFR00989.1 - 2.9e-30 104.7 22.3 2e-29 102.0 22.3 2.3 2 0 0 2 2 2 1 Sprouty protein (Spry) WH1 PF00568.23 KFR00989.1 - 1.1e-10 41.4 0.0 2e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 WH1 domain Meis_PKNOX_N PF16493.5 KFR00990.1 - 1.7e-35 121.2 0.1 2.7e-35 120.5 0.1 1.3 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 Homeobox_KN PF05920.11 KFR00990.1 - 1.1e-20 73.2 1.0 2.1e-20 72.3 1.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFR00990.1 - 2.2e-08 33.8 0.4 4.1e-08 33.0 0.4 1.4 1 0 0 1 1 1 1 Homeodomain TPD PF14811.6 KFR00991.1 - 3.5e-55 185.6 0.3 6.5e-55 184.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function TPD sequence-motif CtsR PF05848.11 KFR00991.1 - 0.16 11.9 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 CtsR N-terminal HTH domain Diphthami_syn_2 PF01902.17 KFR00992.1 - 1.7e-41 142.1 0.1 3.1e-41 141.3 0.1 1.4 1 1 0 1 1 1 1 Diphthamide synthase Aquarius_N PF16399.5 KFR00993.1 - 0 1060.6 0.5 0 1060.2 0.5 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 KFR00993.1 - 5.4e-26 91.4 0.0 9.1e-25 87.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KFR00993.1 - 1.9e-24 86.9 0.0 2.4e-23 83.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KFR00993.1 - 3.7e-07 30.6 0.0 1.7e-06 28.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KFR00993.1 - 2.1e-05 24.6 0.0 6e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KFR00993.1 - 0.0014 18.0 0.1 0.024 13.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KFR00993.1 - 0.0018 18.1 0.0 0.78 9.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.6 KFR00993.1 - 0.0038 17.0 0.2 0.008 16.0 0.2 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KFR00993.1 - 0.0064 16.0 0.0 0.027 14.0 0.0 2.0 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA PF00004.29 KFR00993.1 - 0.0069 16.8 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 KFR00993.1 - 0.053 12.6 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF4088 PF13317.6 KFR00993.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) AAA_16 PF13191.6 KFR00993.1 - 0.2 12.1 0.1 1.9 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain RecA PF00154.21 KFR00993.1 - 0.25 10.8 0.0 0.42 10.0 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Actin PF00022.19 KFR00994.1 - 2.3e-150 500.7 0.0 7.6e-150 499.0 0.0 1.7 1 1 0 1 1 1 1 Actin Sec3-PIP2_bind PF15277.6 KFR00995.1 - 3.7e-24 84.7 0.1 6e-24 84.0 0.1 1.3 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Synaptobrevin PF00957.21 KFR00995.1 - 9.5e-06 25.3 0.6 9.5e-06 25.3 0.6 1.8 2 0 0 2 2 2 1 Synaptobrevin DSX_dimer PF08828.10 KFR00995.1 - 0.2 11.3 0.2 5.1 6.9 0.1 2.3 2 0 0 2 2 2 0 Doublesex dimerisation domain Yae1_N PF09811.9 KFR00998.1 - 2.6e-09 36.6 29.5 0.069 12.9 20.5 3.5 2 1 0 2 2 2 2 Essential protein Yae1, N terminal KH_1 PF00013.29 KFR00999.1 - 4.4e-33 112.9 5.7 9.8e-17 60.6 0.8 3.1 3 0 0 3 3 3 2 KH domain KH_2 PF07650.17 KFR00999.1 - 4.9e-08 32.7 3.6 3e-05 23.8 0.2 2.4 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 KFR00999.1 - 1.4e-06 28.0 2.5 0.0082 16.0 0.0 2.8 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 KFR00999.1 - 0.096 12.8 2.0 1.3 9.2 0.1 2.4 2 0 0 2 2 2 0 NusA-like KH domain V-set PF07686.17 KFR01001.1 - 0.0016 18.6 0.0 0.0019 18.4 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain ATP-synt_ab PF00006.25 KFR01003.1 - 7.6e-23 81.3 0.2 1e-22 80.9 0.2 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain T3SS_ATPase_C PF18269.1 KFR01003.1 - 0.0051 16.6 0.2 0.076 12.9 0.2 2.3 1 1 0 1 1 1 1 T3SS EscN ATPase C-terminal domain ATP-synt_ab PF00006.25 KFR01004.1 - 3.7e-27 95.4 0.0 5.8e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KFR01004.1 - 7.4e-23 80.9 2.5 1.4e-22 79.9 2.5 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 KFR01004.1 - 0.0094 15.2 0.1 0.013 14.7 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain RsgA_GTPase PF03193.16 KFR01004.1 - 0.011 15.7 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase ATPase PF06745.13 KFR01004.1 - 0.013 14.9 0.1 0.019 14.3 0.1 1.3 1 0 0 1 1 1 0 KaiC ATPase_2 PF01637.18 KFR01004.1 - 0.045 13.7 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KFR01004.1 - 0.061 13.0 0.2 0.31 10.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFR01004.1 - 0.065 13.8 0.1 0.13 12.7 0.1 1.5 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 KFR01004.1 - 0.065 13.6 0.3 0.12 12.7 0.3 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KFR01004.1 - 0.14 11.4 0.1 0.19 11.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 KFR01004.1 - 0.15 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KFR01004.1 - 0.16 12.3 0.1 0.35 11.3 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 KFR01004.1 - 0.21 12.0 0.0 0.33 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA helicase CS PF04969.16 KFR01005.1 - 5.5e-08 33.7 0.2 7.7e-08 33.3 0.2 1.2 1 0 0 1 1 1 1 CS domain Pkinase_C PF00433.24 KFR01005.1 - 0.2 12.4 6.5 0.59 10.9 6.5 1.9 2 0 0 2 2 2 0 Protein kinase C terminal domain NAC PF01849.18 KFR01006.1 - 2.4e-25 88.3 1.0 9.9e-25 86.3 0.2 2.2 2 0 0 2 2 2 1 NAC domain RNA_pol_Rpo13 PF12136.8 KFR01006.1 - 0.043 13.7 3.9 0.097 12.6 3.9 1.6 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain DNA_primase_S PF01896.19 KFR01007.1 - 1.9e-27 96.4 0.0 2.7e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 DNA primase small subunit BTB PF00651.31 KFR01008.1 - 1.3e-23 83.3 0.1 2.6e-23 82.3 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFR01008.1 - 1.1e-13 50.9 51.6 2.9e-07 30.6 5.2 9.9 11 0 0 11 11 11 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFR01008.1 - 1.5e-06 28.3 78.6 0.0027 18.1 3.6 9.8 10 0 0 10 10 10 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR01008.1 - 2.2e-06 28.0 75.6 0.19 12.6 2.9 10.4 10 0 0 10 10 10 7 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KFR01008.1 - 1.3e-05 25.9 3.3 1.3e-05 25.9 3.3 4.2 2 2 1 4 4 4 3 Zinc finger C2H2-type, 3 repeats BolA PF01722.18 KFR01008.1 - 0.043 14.1 4.6 6.6 7.1 0.1 3.9 3 1 1 4 4 4 0 BolA-like protein zinc_ribbon_15 PF17032.5 KFR01008.1 - 1.1 10.0 24.9 10 6.9 1.0 5.7 1 1 5 6 6 6 0 zinc-ribbon family Elf1 PF05129.13 KFR01008.1 - 3 7.9 32.1 0.39 10.8 1.7 5.9 3 3 2 5 5 5 0 Transcription elongation factor Elf1 like Myosin_head PF00063.21 KFR01009.1 - 2.4e-251 835.7 0.0 3e-251 835.4 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KFR01009.1 - 9.1e-37 126.6 0.0 1.8e-36 125.6 0.0 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding IQ PF00612.27 KFR01009.1 - 0.00027 20.4 32.4 0.0084 15.8 1.6 5.4 5 0 0 5 5 5 3 IQ calmodulin-binding motif AAA_22 PF13401.6 KFR01009.1 - 0.0072 16.6 0.0 0.084 13.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFR01009.1 - 0.0092 16.4 0.1 0.091 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain NEMP PF10225.9 KFR01010.1 - 1.9e-22 80.2 0.0 2.2e-22 79.9 0.0 1.0 1 0 0 1 1 1 1 NEMP family NEMP PF10225.9 KFR01011.1 - 0.028 14.1 0.7 0.04 13.6 0.7 1.3 1 0 0 1 1 1 0 NEMP family NCD2 PF04905.13 KFR01012.1 - 6.9e-47 158.5 0.8 1e-46 157.9 0.8 1.3 1 0 0 1 1 1 1 NAB conserved region 2 (NCD2) NCD1 PF04904.13 KFR01012.1 - 1.6e-41 140.2 0.0 2.6e-41 139.5 0.0 1.3 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) STAT_bind PF02864.15 KFR01013.1 - 7.4e-41 139.8 1.0 1.3e-40 139.0 1.0 1.4 1 0 0 1 1 1 1 STAT protein, DNA binding domain SH2 PF00017.24 KFR01013.1 - 6.4e-10 39.0 0.0 1.4e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 SH2 domain Big_4 PF07532.11 KFR01013.1 - 0.16 11.8 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 4) Neurexophilin PF06312.12 KFR01014.1 - 8.4e-70 234.5 4.4 2.6e-69 232.9 4.4 1.6 1 1 0 1 1 1 1 Neurexophilin SHMT PF00464.19 KFR01015.1 - 6.7e-207 686.8 0.0 7.8e-207 686.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Coat_F PF07875.12 KFR01015.1 - 0.064 13.5 0.2 0.17 12.2 0.2 1.6 1 0 0 1 1 1 0 Coat F domain STAC2_u1 PF16664.5 KFR01016.1 - 3.2e-08 34.1 0.0 4.4e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Unstructured on SH3 and cysteine-rich domain-containing protein 2 C1_1 PF00130.22 KFR01016.1 - 0.0019 18.0 5.9 0.0068 16.3 6.3 1.7 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.11 KFR01016.1 - 0.052 13.9 5.5 0.099 13.0 5.0 1.7 2 0 0 2 2 2 0 RING-like domain SUZ PF12752.7 KFR01017.1 - 2.9e-12 47.1 5.1 2.9e-12 47.1 5.1 4.5 5 0 0 5 5 5 1 SUZ domain R3H PF01424.22 KFR01017.1 - 9.1e-11 41.6 0.1 2.8e-10 40.0 0.1 1.9 1 0 0 1 1 1 1 R3H domain TUSC2 PF15000.6 KFR01017.1 - 4.4 7.6 6.6 1.5 9.1 0.8 3.1 2 1 1 3 3 3 0 Tumour suppressor candidate 2 zf-C2H2 PF00096.26 KFR01018.1 - 2.3e-21 75.0 28.2 0.0001 22.5 0.5 5.8 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFR01018.1 - 7.7e-13 48.2 40.0 5.2e-07 29.8 1.4 6.6 7 0 0 7 7 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR01018.1 - 1.5e-09 37.8 27.3 0.0016 19.1 0.3 6.1 5 0 0 5 5 5 4 C2H2-type zinc finger FOXP-CC PF16159.5 KFR01018.1 - 1e-08 35.6 20.4 0.00089 19.8 2.4 4.9 1 1 2 4 4 4 2 FOXP coiled-coil domain zf-met PF12874.7 KFR01018.1 - 0.019 15.3 1.8 8.7 6.9 0.2 3.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 KFR01018.1 - 0.049 13.8 16.4 2.9 8.0 2.4 3.4 2 1 1 3 3 3 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 KFR01018.1 - 0.066 13.5 15.9 6.2 7.2 0.2 5.0 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding CHORD PF04968.12 KFR01018.1 - 0.12 13.1 24.2 3.1 8.6 4.7 4.3 2 1 2 4 4 4 0 CHORD zf-H2C2_5 PF13909.6 KFR01018.1 - 0.76 9.6 0.0 0.76 9.6 0.0 4.3 4 0 0 4 4 4 0 C2H2-type zinc-finger domain PcF PF09461.10 KFR01018.1 - 0.81 10.1 8.8 14 6.2 0.4 4.1 3 1 1 4 4 4 0 Phytotoxin PcF protein zf_ZIC PF18366.1 KFR01018.1 - 4.6 7.4 17.4 0.49 10.5 0.7 4.7 3 1 1 5 5 5 0 Zic proteins zinc finger domain RRM_1 PF00076.22 KFR01019.1 - 0.14 12.0 0.0 1.7 8.5 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 1-cysPrx_C PF10417.9 KFR01033.1 - 6.5e-13 48.3 0.3 1e-12 47.7 0.3 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA PF00578.21 KFR01033.1 - 1.7e-12 47.3 0.0 3.1e-12 46.5 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFR01033.1 - 7.2e-05 22.5 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 Redoxin Sprouty PF05210.13 KFR01034.1 - 6.2e-27 94.0 33.1 1.4e-26 92.9 33.1 1.6 1 1 0 1 1 1 1 Sprouty protein (Spry) ATF7IP_BD PF16788.5 KFR01034.1 - 0.23 11.6 1.1 0.34 11.0 1.1 1.2 1 0 0 1 1 1 0 ATF-interacting protein binding domain Ank_2 PF12796.7 KFR01035.1 - 3.5e-104 341.6 23.4 1.3e-14 54.5 0.0 9.8 2 2 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFR01035.1 - 6.3e-100 326.4 20.4 8e-11 42.2 0.0 14.2 3 3 13 16 16 16 14 Ankyrin repeats (many copies) Ank PF00023.30 KFR01035.1 - 2.9e-78 255.2 43.0 6.6e-06 26.3 0.1 19.4 19 0 0 19 19 19 16 Ankyrin repeat Ank_5 PF13857.6 KFR01035.1 - 6.4e-74 243.0 35.4 1.3e-09 38.1 0.1 12.3 5 4 8 13 13 13 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFR01035.1 - 2e-67 215.1 15.7 0.00021 21.5 0.0 18.6 19 0 0 19 19 19 13 Ankyrin repeat NACHT PF05729.12 KFR01035.1 - 0.0029 17.5 0.3 0.017 15.0 0.3 2.3 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KFR01035.1 - 0.003 18.0 0.1 0.047 14.1 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain Cadherin PF00028.17 KFR01036.1 - 0 2049.7 60.1 2.8e-24 85.4 0.4 34.7 34 1 0 34 34 34 34 Cadherin domain Cadherin_2 PF08266.12 KFR01036.1 - 1.6e-51 172.0 0.0 0.018 14.9 0.0 25.7 29 1 0 29 29 29 11 Cadherin-like Laminin_G_2 PF02210.24 KFR01036.1 - 2.4e-39 134.8 0.3 4e-19 69.4 0.0 3.5 3 0 0 3 3 3 2 Laminin G domain Cadherin_3 PF16184.5 KFR01036.1 - 1.4e-33 115.2 63.9 0.2 11.6 0.1 27.1 29 1 1 30 30 30 11 Cadherin-like Laminin_G_1 PF00054.23 KFR01036.1 - 1.4e-31 109.4 0.1 1.5e-17 64.0 0.0 3.7 4 0 0 4 4 4 2 Laminin G domain EGF PF00008.27 KFR01036.1 - 7.1e-25 87.0 92.7 1.1e-06 28.8 8.7 7.4 6 1 0 6 6 6 6 EGF-like domain EGF_CA PF07645.15 KFR01036.1 - 1.3e-10 41.2 26.0 2.9e-07 30.6 6.5 7.4 5 2 2 7 7 7 2 Calcium-binding EGF domain RET_CLD1 PF17756.1 KFR01036.1 - 2.1e-10 40.9 0.0 26 5.1 0.0 14.3 22 0 0 22 22 22 0 RET Cadherin like domain 1 hEGF PF12661.7 KFR01036.1 - 4.9e-07 30.1 100.9 0.00029 21.3 7.6 9.5 10 0 0 10 10 10 5 Human growth factor-like EGF EGF_2 PF07974.13 KFR01036.1 - 1e-05 25.8 92.3 0.25 11.8 8.3 7.0 6 1 0 6 6 6 5 EGF-like domain PDZ PF00595.24 KFR01037.1 - 7.3e-05 23.1 0.3 0.00027 21.2 0.2 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFR01037.1 - 0.00025 20.8 0.1 0.00068 19.4 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFR01037.1 - 0.074 13.4 0.3 0.2 12.0 0.3 1.8 1 1 0 1 1 1 0 PDZ domain HSP70 PF00012.20 KFR01038.1 - 2.6e-173 577.5 12.4 2.6e-165 551.1 0.6 2.8 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 KFR01038.1 - 9.3e-09 34.5 0.0 1.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein MFS_1 PF07690.16 KFR01039.1 - 6.7e-39 133.8 27.6 1.6e-31 109.5 16.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFR01039.1 - 1.1e-09 37.6 10.3 1.1e-09 37.6 10.3 3.6 3 1 0 4 4 4 3 Sugar (and other) transporter SLATT_5 PF18160.1 KFR01039.1 - 0.18 11.1 1.0 0.53 9.6 1.0 1.7 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Pam17 PF08566.10 KFR01039.1 - 0.4 10.5 4.4 3.9 7.3 0.1 3.2 3 1 0 3 3 3 0 Mitochondrial import protein Pam17 DUF2048 PF09752.9 KFR01040.1 - 9e-162 538.1 0.0 1e-161 537.9 0.0 1.0 1 0 0 1 1 1 1 Abhydrolase domain containing 18 Peptidase_S15 PF02129.18 KFR01040.1 - 0.016 14.8 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) La PF05383.17 KFR01041.1 - 9.8e-22 76.8 0.1 2.4e-21 75.5 0.1 1.7 1 0 0 1 1 1 1 La domain Vault PF01505.18 KFR01041.1 - 0.0059 16.8 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 Major Vault Protein repeat domain BMFP PF04380.13 KFR01041.1 - 0.095 13.2 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 Membrane fusogenic activity SGP PF17228.2 KFR01041.1 - 0.59 11.0 4.3 1.7 9.5 4.3 1.7 1 0 0 1 1 1 0 Sulphur globule protein zf-HC5HC2H_2 PF13832.6 KFR01042.1 - 1.2e-32 112.4 2.8 1.2e-32 112.4 2.8 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFR01042.1 - 4e-28 97.5 2.1 4e-28 97.5 2.1 3.8 4 0 0 4 4 4 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KFR01042.1 - 7.9e-13 47.7 6.4 7.9e-13 47.7 6.4 3.6 4 0 0 4 4 4 1 PHD-finger PHD PF00628.29 KFR01042.1 - 9.6e-12 44.6 23.2 2.2e-10 40.3 8.7 3.3 3 0 0 3 3 3 2 PHD-finger EPL1 PF10513.9 KFR01042.1 - 2.5e-06 28.0 0.1 2.5e-06 28.0 0.1 3.7 3 2 0 3 3 2 1 Enhancer of polycomb-like C1_1 PF00130.22 KFR01042.1 - 0.0016 18.3 3.0 0.0016 18.3 3.0 3.2 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KFR01042.1 - 0.006 16.9 18.7 0.14 12.5 4.8 3.7 3 0 0 3 3 3 2 C1 domain zf-RING-like PF08746.11 KFR01042.1 - 0.021 15.1 4.6 0.021 15.1 4.6 3.2 2 0 0 2 2 2 0 RING-like domain FidL_like PF15941.5 KFR01042.1 - 0.12 12.9 0.0 0.32 11.5 0.0 1.7 1 0 0 1 1 1 0 FidL-like putative membrane protein Prok-RING_1 PF14446.6 KFR01042.1 - 2.2 8.3 17.8 0.83 9.6 7.4 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 KFR01042.1 - 6.4 6.4 13.0 3 7.4 6.4 3.1 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING_2 PF13639.6 KFR01042.1 - 8.1 6.9 21.3 0.29 11.5 2.1 3.0 2 1 0 2 2 2 0 Ring finger domain MCM_OB PF17207.3 KFR01043.1 - 0.017 15.0 2.0 0.059 13.2 2.0 2.1 1 0 0 1 1 1 0 MCM OB domain HALZ PF02183.18 KFR01043.1 - 1.7 8.9 32.0 0.18 12.1 1.4 6.9 6 1 0 6 6 6 0 Homeobox associated leucine zipper DUF4462 PF14692.6 KFR01046.1 - 0.081 12.4 0.5 0.13 11.7 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Cadherin PF00028.17 KFR01047.1 - 6.1e-70 231.7 0.9 1.5e-19 70.2 0.0 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_2 PF08266.12 KFR01047.1 - 6.8e-34 115.6 0.1 7.8e-31 105.8 0.1 4.0 4 0 0 4 4 4 1 Cadherin-like Cadherin_C_2 PF16492.5 KFR01047.1 - 2.9e-27 95.2 1.6 9e-27 93.6 1.0 2.2 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal Cadherin_3 PF16184.5 KFR01047.1 - 0.00013 21.9 0.2 1.8 8.6 0.0 4.6 5 0 0 5 5 5 1 Cadherin-like RET_CLD1 PF17756.1 KFR01047.1 - 0.0013 19.0 0.0 5.6 7.3 0.0 4.1 3 1 1 4 4 4 1 RET Cadherin like domain 1 Cadherin PF00028.17 KFR01049.1 - 1.1e-83 275.8 2.8 2.1e-16 60.1 0.0 6.4 5 1 1 6 6 6 6 Cadherin domain Cadherin_2 PF08266.12 KFR01049.1 - 1.7e-14 53.4 1.4 3.8e-13 49.1 0.1 3.5 5 0 0 5 5 5 1 Cadherin-like Cadherin_3 PF16184.5 KFR01049.1 - 1.3e-05 25.2 7.3 0.34 10.9 0.2 5.2 4 1 1 5 5 5 2 Cadherin-like Cadherin_C_2 PF16492.5 KFR01049.1 - 0.0023 18.6 3.2 0.0036 18.0 0.8 2.8 2 1 0 2 2 2 1 Cadherin cytoplasmic C-terminal VEGF_C PF14554.6 KFR01049.1 - 0.07 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 VEGF heparin-binding domain Syndecan PF01034.20 KFR01049.1 - 0.081 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain FAM176 PF14851.6 KFR01049.1 - 0.25 11.0 1.9 0.5 10.0 0.4 2.1 2 0 0 2 2 2 0 FAM176 family AA_permease_2 PF13520.6 KFR01051.1 - 2.2e-59 201.4 40.8 2.6e-59 201.2 40.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFR01051.1 - 1.6e-30 106.1 37.8 2.7e-30 105.4 37.8 1.3 1 1 0 1 1 1 1 Amino acid permease Exo_endo_phos PF03372.23 KFR01052.1 - 4.9e-23 81.9 0.0 6.2e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KFR01052.1 - 0.0025 17.6 0.0 0.013 15.4 0.0 2.3 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase E3_UbLigase_EDD PF11547.8 KFR01052.1 - 0.089 12.5 0.7 2.5 7.9 0.1 2.7 3 0 0 3 3 3 0 E3 ubiquitin ligase EDD NARP1 PF12569.8 KFR01054.1 - 4.7e-224 745.1 24.1 4.7e-224 745.1 24.1 1.6 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 KFR01054.1 - 1.6e-15 55.9 24.7 0.00051 20.0 0.1 9.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFR01054.1 - 1.5e-13 50.3 7.8 0.039 14.8 0.0 9.2 7 3 3 10 10 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFR01054.1 - 6e-12 45.9 19.7 0.0035 17.8 0.3 7.7 5 2 4 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFR01054.1 - 4.1e-11 42.2 26.8 0.00038 20.5 0.1 9.0 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFR01054.1 - 1.4e-10 41.6 7.0 0.1 13.3 0.0 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFR01054.1 - 1.8e-09 37.0 25.2 0.0025 17.6 0.2 8.9 9 0 0 9 9 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFR01054.1 - 6.1e-08 32.8 27.0 0.00068 19.8 0.8 6.2 4 2 3 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KFR01054.1 - 1.6e-07 30.8 9.5 0.00025 20.7 0.1 5.4 7 0 0 7 7 7 2 TPR repeat TPR_9 PF13371.6 KFR01054.1 - 2.9e-06 27.3 5.1 0.31 11.2 0.2 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFR01054.1 - 4.2e-06 27.0 20.8 0.71 10.2 0.1 7.3 6 3 1 7 7 7 3 Tetratricopeptide repeat TPR_4 PF07721.14 KFR01054.1 - 0.0001 22.6 0.1 5.1 8.0 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFR01054.1 - 0.00059 19.7 14.3 1.2 9.4 0.1 7.5 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFR01054.1 - 0.0012 18.2 3.2 0.0012 18.2 3.2 4.0 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFR01054.1 - 0.0024 18.4 11.0 12 6.7 0.0 7.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_3 PF07720.12 KFR01054.1 - 0.069 13.2 1.8 18 5.5 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Vfa1 PF08432.10 KFR01054.1 - 0.34 11.2 14.2 1.1 9.6 14.2 1.8 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Fis1_TPR_C PF14853.6 KFR01054.1 - 0.8 9.8 10.5 23 5.1 0.1 5.2 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat Peptidase_S30 PF01577.16 KFR01054.1 - 1.1 8.9 8.8 1.9 8.0 8.8 1.3 1 0 0 1 1 1 0 Potyvirus P1 protease F-protein PF00469.20 KFR01054.1 - 1.2 8.7 7.4 1.2 8.7 5.4 1.9 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef TPR_10 PF13374.6 KFR01054.1 - 1.5 8.8 13.5 1.5e+02 2.5 0.0 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat PPR PF01535.20 KFR01054.1 - 5.5 7.5 9.9 6.5 7.2 0.0 5.8 7 0 0 7 7 6 0 PPR repeat DDRGK PF09756.9 KFR01054.1 - 6.9 6.2 21.2 13 5.3 18.3 2.3 2 0 0 2 2 2 0 DDRGK domain TMEM51 PF15345.6 KFR01054.1 - 7.5 6.3 6.3 13 5.6 6.3 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 CD20 PF04103.15 KFR01055.1 - 1.5e-07 31.6 14.9 9.8e-07 29.0 14.9 1.9 1 1 0 1 1 1 1 CD20-like family DUF3975 PF13126.6 KFR01055.1 - 0.11 12.9 2.0 0.31 11.5 2.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3975) gpUL132 PF11359.8 KFR01055.1 - 1.6 8.3 3.7 2.4 7.7 3.3 1.4 1 1 0 1 1 1 0 Glycoprotein UL132 MORN PF02493.20 KFR01056.1 - 4.2e-13 48.3 21.8 0.0015 18.3 0.9 6.7 7 0 0 7 7 7 4 MORN repeat SET PF00856.28 KFR01056.1 - 1e-06 29.2 0.0 1.3e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 SET domain MORN_2 PF07661.13 KFR01056.1 - 0.36 11.2 8.8 0.4 11.1 0.0 4.9 6 0 0 6 6 6 0 MORN repeat variant MAPEG PF01124.18 KFR01057.1 - 2.1e-16 60.0 1.5 2.4e-16 59.8 1.5 1.0 1 0 0 1 1 1 1 MAPEG family DUF2205 PF10224.9 KFR01059.1 - 8e-28 96.2 4.1 1.1e-27 95.8 4.1 1.2 1 0 0 1 1 1 1 Short coiled-coil protein HALZ PF02183.18 KFR01059.1 - 0.0018 18.5 8.3 0.051 13.8 2.0 3.0 1 1 1 2 2 2 2 Homeobox associated leucine zipper bZIP_1 PF00170.21 KFR01059.1 - 0.0066 16.5 0.9 0.0066 16.5 0.9 1.9 1 1 1 2 2 2 1 bZIP transcription factor YabA PF06156.13 KFR01059.1 - 0.0085 16.7 4.5 0.011 16.4 3.9 1.5 1 1 1 2 2 2 1 Initiation control protein YabA CENP-H PF05837.12 KFR01059.1 - 0.012 16.0 3.0 0.012 16.0 3.0 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) FlaC_arch PF05377.11 KFR01059.1 - 0.019 15.3 1.1 0.019 15.3 1.1 2.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DASH_Dad4 PF08650.10 KFR01059.1 - 0.043 13.8 2.6 0.052 13.5 1.7 1.7 1 1 1 2 2 2 0 DASH complex subunit Dad4 DUF2683 PF10884.8 KFR01059.1 - 0.053 13.8 0.3 0.069 13.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2683) ZapB PF06005.12 KFR01059.1 - 0.081 13.4 7.7 0.18 12.2 7.9 1.5 1 1 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 KFR01059.1 - 0.28 11.0 5.1 0.11 12.2 1.3 1.9 1 1 1 2 2 2 0 Septum formation initiator DUF349 PF03993.12 KFR01059.1 - 0.33 11.3 2.6 0.51 10.7 1.9 1.6 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) V_ATPase_I PF01496.19 KFR01059.1 - 0.37 8.6 4.5 0.4 8.5 4.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Calreticulin PF00262.18 KFR01060.1 - 4.3e-163 542.4 16.5 5e-163 542.2 16.5 1.0 1 0 0 1 1 1 1 Calreticulin family Glyco_transf_54 PF04666.13 KFR01061.1 - 3.4e-126 420.0 1.1 4.1e-126 419.7 1.1 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region APC_N_CC PF16689.5 KFR01061.1 - 0.082 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain RabGAP-TBC PF00566.18 KFR01063.1 - 8.9e-47 159.5 0.1 4.6e-46 157.2 0.0 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GRAM PF02893.20 KFR01063.1 - 1.6e-41 140.8 1.6 2.5e-22 78.9 0.1 2.6 2 0 0 2 2 2 2 GRAM domain EF-hand_1 PF00036.32 KFR01063.1 - 0.012 15.1 0.1 0.33 10.6 0.0 2.9 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 KFR01063.1 - 0.099 12.6 0.1 0.77 9.8 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain zf-RING_2 PF13639.6 KFR01064.1 - 2.6e-12 46.9 6.6 5.3e-12 45.9 6.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFR01064.1 - 4.3e-10 39.2 1.5 1e-09 38.0 1.5 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFR01064.1 - 4e-08 32.9 6.4 7.9e-08 32.0 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFR01064.1 - 1.9e-07 30.8 4.7 3.8e-07 29.9 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFR01064.1 - 4.3e-07 29.8 3.5 8.3e-07 28.9 3.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFR01064.1 - 3.2e-06 27.3 8.0 8.9e-06 25.9 8.0 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFR01064.1 - 3.8e-06 26.6 4.4 3.8e-06 26.6 4.4 1.7 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 PA PF02225.22 KFR01064.1 - 5.2e-06 26.4 0.2 1e-05 25.5 0.2 1.5 1 0 0 1 1 1 1 PA domain zf-C3HC4_3 PF13920.6 KFR01064.1 - 1.5e-05 24.8 3.6 2.7e-05 23.9 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFR01064.1 - 1.9e-05 24.6 4.7 3.8e-05 23.6 4.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger PspB PF06667.12 KFR01064.1 - 0.0028 17.7 0.2 0.0049 16.9 0.2 1.3 1 0 0 1 1 1 1 Phage shock protein B CrgA PF06781.12 KFR01064.1 - 0.0034 17.4 0.2 0.0073 16.3 0.2 1.6 1 0 0 1 1 1 1 Cell division protein CrgA Ninjurin PF04923.12 KFR01064.1 - 0.0038 17.1 0.5 0.0084 16.0 0.5 1.5 1 0 0 1 1 1 1 Ninjurin zf-ANAPC11 PF12861.7 KFR01064.1 - 0.011 15.8 2.3 0.021 14.9 2.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger BatD PF13584.6 KFR01064.1 - 0.04 12.7 0.0 0.059 12.2 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance Zn_ribbon_17 PF17120.5 KFR01064.1 - 0.089 12.4 5.1 0.44 10.2 5.5 1.9 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 KFR01064.1 - 0.31 11.0 7.7 0.47 10.4 4.3 2.4 2 0 0 2 2 2 0 PHD-finger zf-C3H2C3 PF17122.5 KFR01064.1 - 4.5 7.4 9.6 0.14 12.3 2.7 2.1 2 0 0 2 2 2 0 Zinc-finger RINGv PF12906.7 KFR01064.1 - 6.3 7.0 8.2 1.3 9.2 4.4 1.9 2 0 0 2 2 1 0 RING-variant domain NOA36 PF06524.12 KFR01065.1 - 2.5e-167 555.8 44.6 3.1e-167 555.5 44.6 1.0 1 0 0 1 1 1 1 NOA36 protein IL15 PF02372.15 KFR01066.1 - 7.5e-42 142.6 9.5 8.9e-42 142.3 9.5 1.1 1 0 0 1 1 1 1 Interleukin 15 NHR2 PF08788.11 KFR01067.1 - 0.16 11.8 0.8 0.4 10.5 0.1 2.1 2 0 0 2 2 2 0 NHR2 domain like UCH PF00443.29 KFR01068.1 - 1.5e-39 136.1 0.1 2.3e-39 135.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFR01068.1 - 1.2e-18 67.8 8.5 4.6e-17 62.6 8.5 3.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SNF2_N PF00176.23 KFR01069.1 - 7.3e-80 268.3 1.2 1.2e-79 267.6 0.3 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.10 KFR01069.1 - 1.5e-43 147.5 2.4 5.2e-43 145.7 2.4 2.0 1 0 0 1 1 1 1 SLIDE HAND PF09110.11 KFR01069.1 - 2.5e-31 108.7 2.1 2.5e-31 108.7 2.1 3.4 4 0 0 4 4 4 1 HAND Helicase_C PF00271.31 KFR01069.1 - 3.5e-20 72.4 0.0 2.9e-19 69.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFR01069.1 - 1.2e-11 44.9 0.0 9.4e-11 42.0 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFR01069.1 - 9.2e-07 28.8 0.0 3.3e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 KFR01069.1 - 8e-05 22.7 0.3 0.37 11.0 0.0 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain HDA2-3 PF11496.8 KFR01069.1 - 0.00012 21.3 0.0 0.00029 20.1 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DBINO PF13892.6 KFR01069.1 - 0.0016 18.8 0.5 0.0016 18.8 0.5 3.7 5 0 0 5 5 5 1 DNA-binding domain GSDH PF07995.11 KFR01070.1 - 1.3e-19 70.7 0.0 1.9e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Folate_rec PF03024.14 KFR01070.1 - 1.1e-17 64.4 7.8 1.1e-17 64.4 7.8 2.5 2 0 0 2 2 2 1 Folate receptor family EGF_2 PF07974.13 KFR01070.1 - 0.0017 18.7 11.1 0.0017 18.7 11.1 3.4 2 1 1 3 3 3 2 EGF-like domain ANAPC10 PF03256.16 KFR01071.1 - 4.2e-83 277.5 0.0 5e-83 277.3 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 KFR01071.1 - 4.5e-05 23.6 0.0 5.9e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain PITH PF06201.13 KFR01071.1 - 0.0018 18.5 0.1 0.011 15.9 0.1 1.9 1 1 1 2 2 2 1 PITH domain ABC_tran PF00005.27 KFR01072.1 - 7.4e-38 130.2 0.0 1.5e-18 67.6 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 KFR01072.1 - 1.5e-14 53.5 7.2 4.2e-14 52.1 7.2 1.9 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 KFR01072.1 - 4.2e-11 42.7 1.6 0.0021 17.5 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFR01072.1 - 9.5e-11 42.0 2.9 0.17 11.7 0.7 4.4 3 2 0 5 5 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 KFR01072.1 - 1.1e-07 31.3 1.6 1.1e-07 31.3 1.6 3.8 5 0 0 5 5 4 1 4Fe-4S binding domain AAA_16 PF13191.6 KFR01072.1 - 1.1e-05 25.8 0.0 0.027 14.8 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 KFR01072.1 - 1.5e-05 24.9 0.0 0.22 11.2 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 KFR01072.1 - 3.1e-05 24.4 0.0 0.05 14.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KFR01072.1 - 4e-05 23.6 0.0 0.14 12.0 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase Fer4_6 PF12837.7 KFR01072.1 - 4.3e-05 23.4 0.9 4.3e-05 23.4 0.9 3.5 4 0 0 4 4 3 1 4Fe-4S binding domain AAA_22 PF13401.6 KFR01072.1 - 4.9e-05 23.6 0.0 0.011 16.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFR01072.1 - 9.3e-05 22.1 0.4 0.54 10.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 KFR01072.1 - 0.00054 19.9 0.4 0.091 12.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Rad17 PF03215.15 KFR01072.1 - 0.0013 18.7 0.0 0.67 9.8 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_30 PF13604.6 KFR01072.1 - 0.0016 18.2 0.2 0.079 12.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KFR01072.1 - 0.0019 18.7 2.7 0.061 13.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain Fer4_7 PF12838.7 KFR01072.1 - 0.002 18.7 9.5 0.0057 17.2 1.0 3.2 2 2 2 4 4 4 2 4Fe-4S dicluster domain AAA_33 PF13671.6 KFR01072.1 - 0.0022 18.2 0.0 0.49 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KFR01072.1 - 0.0022 17.8 0.2 0.57 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFR01072.1 - 0.0024 18.2 0.0 2.1 8.8 0.0 3.4 3 0 0 3 3 3 1 RNA helicase SRP54 PF00448.22 KFR01072.1 - 0.003 17.2 1.9 0.31 10.6 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_2 PF12797.7 KFR01072.1 - 0.0031 17.5 0.7 0.0031 17.5 0.7 3.1 3 0 0 3 3 2 1 4Fe-4S binding domain Fer4_9 PF13187.6 KFR01072.1 - 0.0063 16.7 10.0 0.0063 16.7 10.0 2.0 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KFR01072.1 - 0.0085 16.2 1.7 0.0085 16.2 1.7 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_28 PF13521.6 KFR01072.1 - 0.011 16.0 0.2 4.4 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_21 PF14697.6 KFR01072.1 - 0.011 15.8 13.3 0.031 14.4 12.9 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain TsaE PF02367.17 KFR01072.1 - 0.014 15.4 0.2 0.23 11.5 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_16 PF13484.6 KFR01072.1 - 0.028 15.4 0.9 0.028 15.4 0.9 2.9 3 0 0 3 3 2 0 4Fe-4S double cluster binding domain AAA_18 PF13238.6 KFR01072.1 - 0.041 14.4 0.0 9.1 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 KFR01072.1 - 0.079 12.2 0.1 4 6.6 0.0 2.6 3 0 0 3 3 3 0 Septin AAA_5 PF07728.14 KFR01072.1 - 0.083 12.9 1.1 1.2 9.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 KFR01072.1 - 0.085 12.9 0.7 19 5.4 0.0 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.22 KFR01072.1 - 0.089 12.0 0.0 6.9 5.8 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain VirE PF05272.11 KFR01072.1 - 0.1 12.3 0.0 5.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E AAA_7 PF12775.7 KFR01072.1 - 0.12 11.9 0.2 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region MeaB PF03308.16 KFR01072.1 - 0.13 11.2 0.1 8 5.4 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 KFR01072.1 - 0.15 11.8 0.1 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SbcCD_C PF13558.6 KFR01072.1 - 0.21 11.9 0.1 14 6.0 0.0 2.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 KFR01072.1 - 0.39 10.8 3.1 29 4.7 0.0 3.6 3 1 1 4 4 3 0 AAA domain Fer4_17 PF13534.6 KFR01072.1 - 0.92 10.1 9.1 0.09 13.3 0.7 2.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 KFR01072.1 - 5.9 7.7 15.1 0.45 11.1 2.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain OTU PF02338.19 KFR01073.1 - 3.5e-14 53.4 0.0 7.4e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease SMN PF06003.12 KFR01073.1 - 0.0028 17.0 0.0 0.0028 17.0 0.0 3.9 5 0 0 5 5 5 1 Survival motor neuron protein (SMN) Peptidase_C65 PF10275.9 KFR01073.1 - 0.036 13.5 0.8 6.9 6.0 0.1 2.5 1 1 1 2 2 2 0 Peptidase C65 Otubain THEG4 PF15834.5 KFR01073.1 - 9.4 6.2 8.3 16 5.4 6.3 2.6 1 1 1 2 2 2 0 Testis highly expressed protein 4 MH2 PF03166.14 KFR01074.1 - 2.1e-75 253.1 1.3 2.8e-75 252.6 1.3 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 KFR01074.1 - 2.2e-42 143.5 1.2 5.6e-42 142.1 1.2 1.7 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.9 KFR01074.1 - 0.00023 21.0 0.0 0.00041 20.2 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 DUF4223 PF13978.6 KFR01074.1 - 0.13 12.3 0.8 0.27 11.2 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) MeaB PF03308.16 KFR01075.1 - 9.1e-95 316.7 0.2 1.2e-94 316.2 0.2 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KFR01075.1 - 1.9e-05 25.0 1.4 0.0011 19.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 KFR01075.1 - 5.4e-05 22.8 0.0 0.00038 20.1 0.0 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 KFR01075.1 - 0.00019 21.3 0.0 0.00044 20.1 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 KFR01075.1 - 0.0036 17.0 0.0 0.0073 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KFR01075.1 - 0.011 16.3 0.1 0.039 14.5 0.0 2.0 2 1 0 2 2 2 0 ABC transporter MnmE_helical PF12631.7 KFR01075.1 - 0.016 15.3 0.0 0.029 14.5 0.0 1.4 1 1 0 1 1 1 0 MnmE helical domain MMR_HSR1 PF01926.23 KFR01075.1 - 0.018 15.1 0.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 KFR01075.1 - 0.024 14.5 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_16 PF13191.6 KFR01075.1 - 0.027 14.9 0.3 0.18 12.2 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain Thymidylate_kin PF02223.17 KFR01075.1 - 0.029 14.1 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase AAA_23 PF13476.6 KFR01075.1 - 0.036 14.6 0.1 0.083 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFR01075.1 - 0.047 13.9 0.4 0.44 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KFR01075.1 - 0.052 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFR01075.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CbiA PF01656.23 KFR01075.1 - 0.11 12.6 0.0 0.24 11.4 0.0 1.7 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Mg_chelatase PF01078.21 KFR01075.1 - 0.13 11.6 0.1 0.8 9.0 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SRP54 PF00448.22 KFR01075.1 - 0.13 11.8 0.0 0.71 9.5 0.0 2.1 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 KFR01075.1 - 0.14 12.7 0.2 0.41 11.2 0.1 1.9 2 0 0 2 2 1 0 AAA domain zf-C2H2 PF00096.26 KFR01076.1 - 3.4e-15 55.5 77.4 0.0015 18.9 0.2 9.3 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFR01076.1 - 8.9e-14 50.9 54.1 0.00056 19.6 3.1 7.5 7 0 0 7 7 7 5 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KFR01076.1 - 6.9e-09 35.7 77.3 0.00057 20.2 4.7 11.3 11 1 0 11 11 11 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR01076.1 - 5.7e-08 32.9 77.4 0.0065 17.2 0.4 9.6 9 0 0 9 9 9 4 C2H2-type zinc finger zf-MYST PF17772.1 KFR01076.1 - 0.0013 18.3 5.1 0.82 9.3 1.3 3.3 2 1 1 3 3 3 2 MYST family zinc finger domain zf-C2H2_6 PF13912.6 KFR01076.1 - 0.0027 17.7 0.3 0.0027 17.7 0.3 6.3 8 1 0 8 8 7 2 C2H2-type zinc finger zf-met PF12874.7 KFR01076.1 - 0.0045 17.3 63.0 0.8 10.2 2.8 9.2 9 0 0 9 9 8 6 Zinc-finger of C2H2 type SRP54_N PF02881.19 KFR01076.1 - 0.017 15.3 3.6 6.8 7.0 0.0 3.6 3 0 0 3 3 3 0 SRP54-type protein, helical bundle domain GAGA PF09237.11 KFR01076.1 - 0.96 9.3 0.0 0.96 9.3 0.0 4.8 5 0 0 5 5 5 0 GAGA factor zf-C2H2_jaz PF12171.8 KFR01076.1 - 1.7 9.0 0.0 0.054 13.8 0.9 8.0 8 0 0 8 8 7 0 Zinc-finger double-stranded RNA-binding OrsD PF12013.8 KFR01076.1 - 5.5 7.5 29.7 10 6.6 7.8 5.7 4 1 1 5 5 5 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_7 PF15269.6 KFR01076.1 - 7.8 6.7 45.0 0.17 12.0 1.2 7.5 5 2 3 8 8 8 0 Zinc-finger LSM PF01423.22 KFR01077.1 - 8.3e-20 70.3 0.1 9.4e-20 70.1 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFR01077.1 - 4.1e-05 23.6 0.0 4.8e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KFR01077.1 - 0.027 14.6 0.1 0.029 14.4 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain Reeler PF02014.16 KFR01078.1 - 4.7e-30 105.0 0.0 5.4e-30 104.8 0.0 1.0 1 0 0 1 1 1 1 Reeler domain SBF_like PF13593.6 KFR01079.1 - 3.7e-73 246.6 21.7 4.1e-73 246.4 21.7 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 KFR01079.1 - 2.6e-16 59.9 12.5 2.6e-16 59.9 12.5 2.1 2 1 0 2 2 2 1 Sodium Bile acid symporter family Phtf-FEM1B_bdg PF12129.8 KFR01079.1 - 1.3 8.9 6.8 0.7 9.7 0.4 2.6 2 1 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor Oxidored_q4 PF00507.19 KFR01079.1 - 2.8 8.2 9.2 0.19 11.9 2.7 2.4 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF373 PF04123.13 KFR01079.1 - 5.9 6.2 7.8 77 2.6 8.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Pou PF00157.17 KFR01080.1 - 2.7e-31 107.3 0.0 4.9e-31 106.5 0.0 1.4 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KFR01080.1 - 8.8e-07 28.7 0.1 2.4e-06 27.3 0.1 1.8 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 KFR01080.1 - 0.00037 20.8 0.0 0.008 16.5 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain TPR_12 PF13424.6 KFR01081.1 - 1.6e-12 47.5 17.1 9.9e-05 22.6 0.0 5.2 3 1 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFR01081.1 - 1.6e-08 34.1 13.7 0.00012 22.0 0.1 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KFR01081.1 - 5.6e-08 32.5 8.1 3.4e-06 26.7 0.2 3.2 1 1 2 3 3 3 2 MalT-like TPR region TPR_2 PF07719.17 KFR01081.1 - 1.6e-07 30.9 16.2 0.013 15.6 0.1 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFR01081.1 - 2.7e-07 30.1 14.7 0.00019 21.1 0.3 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFR01081.1 - 0.00029 20.6 7.3 0.3 11.2 0.1 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFR01081.1 - 0.0004 20.2 2.6 0.02 14.7 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFR01081.1 - 0.0014 19.2 7.7 2.6 9.1 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFR01081.1 - 0.0015 18.1 3.3 0.3 10.8 0.7 4.1 4 0 0 4 4 3 1 TPR repeat TPR_19 PF14559.6 KFR01081.1 - 0.007 16.9 3.5 7.8 7.1 0.1 4.0 2 1 2 4 4 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 KFR01081.1 - 0.01 15.3 0.1 2.1 7.8 0.2 2.8 2 0 0 2 2 2 0 SHNi-TPR TPR_20 PF14561.6 KFR01081.1 - 0.12 12.7 9.7 15 6.0 0.1 5.4 3 1 3 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFR01081.1 - 0.26 11.5 12.8 0.17 12.1 0.3 4.3 2 1 4 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 KFR01081.1 - 1.7 8.3 9.1 1.3 8.8 0.1 3.2 2 1 2 4 4 4 0 26S proteasome subunit RPN7 MIT PF04212.18 KFR01081.1 - 1.7 8.7 5.3 2.3 8.3 0.1 3.6 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 KFR01081.1 - 5 8.0 10.6 71 4.4 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFR01081.1 - 8.5 7.3 9.8 57 4.8 0.1 4.4 5 0 0 5 5 3 0 Tetratricopeptide repeat 7tm_1 PF00001.21 KFR01082.1 - 4e-35 121.4 9.4 4e-35 121.4 9.4 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR01082.1 - 0.0036 16.7 15.4 0.058 12.8 12.7 3.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFR01082.1 - 0.006 16.3 2.7 0.0093 15.7 2.6 1.6 1 1 0 1 1 1 1 Olfactory receptor Solute_trans_a PF03619.16 KFR01083.1 - 2.1e-101 338.9 19.7 2.5e-101 338.7 19.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha PrmA PF06325.13 KFR01084.1 - 3.3e-10 39.9 0.0 1.6e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) TPR_2 PF07719.17 KFR01084.1 - 5.2e-08 32.4 0.6 0.0026 17.7 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Methyltransf_18 PF12847.7 KFR01084.1 - 5.5e-06 26.4 0.0 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFR01084.1 - 5.8e-06 26.9 0.0 1.5e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TPR_14 PF13428.6 KFR01084.1 - 4.6e-05 23.9 0.6 0.09 13.6 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFR01084.1 - 5e-05 22.9 1.0 0.27 11.1 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat MTS PF05175.14 KFR01084.1 - 0.0014 18.2 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KFR01084.1 - 0.0027 17.5 0.0 0.0056 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KFR01084.1 - 0.0044 16.4 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KFR01084.1 - 0.0056 17.3 0.0 0.016 15.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain TPR_11 PF13414.6 KFR01084.1 - 0.0088 15.7 0.0 2.6 7.8 0.0 2.8 2 0 0 2 2 2 1 TPR repeat Methyltransf_16 PF10294.9 KFR01084.1 - 0.0092 15.7 0.2 0.024 14.4 0.0 1.7 2 0 0 2 2 2 1 Lysine methyltransferase DREV PF05219.12 KFR01084.1 - 0.032 13.3 0.0 0.062 12.4 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Met_10 PF02475.16 KFR01084.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein RrnaAD PF00398.20 KFR01084.1 - 0.16 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TPR_16 PF13432.6 KFR01084.1 - 0.19 12.4 0.1 0.53 11.0 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat BAR_3 PF16746.5 KFR01085.1 - 1.1e-64 218.4 17.5 1.9e-64 217.7 17.5 1.4 1 0 0 1 1 1 1 BAR domain of APPL family RhoGAP PF00620.27 KFR01085.1 - 3.9e-40 137.2 0.1 3.9e-40 137.2 0.1 2.6 3 0 0 3 3 3 1 RhoGAP domain SH3_9 PF14604.6 KFR01085.1 - 6.3e-10 38.8 0.0 1.5e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFR01085.1 - 2.5e-07 30.2 0.0 4.9e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 KFR01085.1 - 1.2e-06 29.0 0.0 5e-06 27.0 0.0 2.1 1 0 0 1 1 1 1 PH domain SH3_2 PF07653.17 KFR01085.1 - 8.1e-05 22.2 0.0 0.00017 21.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PhaP_Bmeg PF09602.10 KFR01085.1 - 0.59 10.1 10.3 1.2 9.0 10.1 1.7 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Cas_DxTHG PF09455.10 KFR01085.1 - 2.8 7.4 10.3 5.2 6.6 10.3 1.3 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family zf-C4 PF00105.18 KFR01086.1 - 1.5e-28 99.0 13.0 2.8e-28 98.2 13.0 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFR01086.1 - 1.1e-13 51.3 0.1 1.7e-13 50.7 0.1 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Pkinase PF00069.25 KFR01087.1 - 6.6e-70 235.5 0.0 1e-69 234.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DCX PF03607.17 KFR01087.1 - 1.2e-42 143.9 0.2 3.9e-22 78.1 0.0 2.6 2 0 0 2 2 2 2 Doublecortin Pkinase_Tyr PF07714.17 KFR01087.1 - 5.6e-29 101.2 0.0 8.7e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR01087.1 - 0.0047 16.3 0.0 0.017 14.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFR01087.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Beach PF02138.18 KFR01089.1 - 3.7e-115 384.1 1.3 4.4e-115 383.8 1.3 1.0 1 0 0 1 1 1 1 Beige/BEACH domain SUKH_6 PF14568.6 KFR01089.1 - 0.0087 16.5 0.1 0.048 14.1 0.0 2.0 2 0 0 2 2 2 1 SMI1-KNR4 cell-wall HIT PF01230.23 KFR01093.1 - 1.1e-14 54.9 0.0 1.2e-14 54.8 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KFR01093.1 - 0.00046 20.7 0.0 0.00051 20.5 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding OLF PF02191.16 KFR01095.1 - 5.8e-66 222.6 0.0 6.6e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 Olfactomedin-like domain Gal_Lectin PF02140.18 KFR01095.1 - 1.1e-06 29.0 0.0 1.8e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Galactose binding lectin domain V-set PF07686.17 KFR01096.1 - 8.6e-10 38.8 0.0 1e-09 38.5 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFR01096.1 - 0.016 15.8 0.0 0.03 14.9 0.0 1.5 1 1 0 1 1 1 0 Immunoglobulin domain Keratin PF02422.16 KFR01097.1 - 8.9e-36 121.5 13.7 9.6e-36 121.4 13.7 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFR01133.1 - 9.8e-26 89.3 12.5 1e-25 89.2 12.5 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFR01134.1 - 9.8e-26 89.3 12.5 1e-25 89.2 12.5 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFR01135.1 - 9.8e-26 89.3 12.5 1e-25 89.2 12.5 1.0 1 0 0 1 1 1 1 Keratin PI3K_1B_p101 PF10486.9 KFR01141.1 - 0.092 10.5 0.6 0.095 10.5 0.6 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CUB PF00431.20 KFR01167.1 - 3.7e-169 551.9 6.3 6.2e-42 142.4 0.3 5.2 5 0 0 5 5 5 5 CUB domain Astacin PF01400.24 KFR01167.1 - 3.4e-70 235.5 1.3 4.5e-70 235.2 0.0 1.8 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) FXa_inhibition PF14670.6 KFR01167.1 - 1.1e-15 57.6 37.8 6.8e-09 35.9 12.1 3.2 3 0 0 3 3 2 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 KFR01167.1 - 7.7e-12 45.2 31.1 1.7e-06 28.1 10.8 2.8 2 0 0 2 2 2 2 Calcium-binding EGF domain cEGF PF12662.7 KFR01167.1 - 1.1e-09 38.1 8.8 5.2e-05 23.1 1.2 3.2 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF_3 PF12947.7 KFR01167.1 - 3.7e-07 30.2 22.7 0.0011 19.1 8.5 2.9 2 0 0 2 2 2 2 EGF domain CUB_2 PF02408.20 KFR01167.1 - 7.6e-05 22.5 1.4 6.9 6.5 0.0 4.6 4 1 0 4 4 4 2 CUB-like domain EGF PF00008.27 KFR01167.1 - 0.00017 21.8 26.0 0.0011 19.2 7.6 3.0 2 0 0 2 2 2 2 EGF-like domain Peptidase_M10 PF00413.24 KFR01167.1 - 0.0017 18.2 0.1 0.55 10.1 0.0 2.6 2 0 0 2 2 2 2 Matrixin Reprolysin_4 PF13583.6 KFR01167.1 - 0.029 14.0 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like hEGF PF12661.7 KFR01167.1 - 0.31 11.8 23.5 1.8 9.3 5.6 3.5 2 1 0 2 2 2 0 Human growth factor-like EGF Kunitz_BPTI PF00014.23 KFR01168.1 - 5.4e-27 93.8 24.1 1.7e-14 53.8 10.5 2.0 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Methyltransf_15 PF09445.10 KFR01168.1 - 0.3 10.6 1.3 10 5.6 0.1 2.0 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase EPTP PF03736.17 KFR01169.1 - 2.2e-72 238.8 11.0 1.6e-11 44.0 0.0 7.3 7 0 0 7 7 7 7 EPTP domain LRR_8 PF13855.6 KFR01169.1 - 3.6e-22 77.9 12.5 1.3e-13 50.5 6.1 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_5 PF13306.6 KFR01169.1 - 7.1e-09 35.7 0.1 1.4e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFR01169.1 - 1.3e-06 28.6 10.5 0.0014 19.0 1.1 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFR01169.1 - 1.8e-05 24.3 0.2 3.2e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRRCT PF01463.24 KFR01169.1 - 0.00024 21.4 0.1 0.0029 18.0 0.1 2.8 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain DBP10CT PF08147.12 KFR01169.1 - 0.034 14.4 0.3 13 6.1 0.0 3.4 3 0 0 3 3 3 0 DBP10CT (NUC160) domain DUF2671 PF10877.8 KFR01169.1 - 0.085 12.7 1.0 2.5 8.0 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2671) TPKR_C2 PF16920.5 KFR01169.1 - 0.15 12.3 1.4 2.6 8.2 0.2 3.2 2 0 0 2 2 2 0 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_1 PF00560.33 KFR01169.1 - 0.21 12.3 9.6 8.2 7.4 0.5 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat TB2_DP1_HVA22 PF03134.19 KFR01170.1 - 7.6e-22 77.0 8.9 1e-21 76.6 8.9 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family NUDIX PF00293.28 KFR01171.1 - 1.5e-19 70.4 0.5 2.5e-19 69.6 0.5 1.3 1 0 0 1 1 1 1 NUDIX domain RAI16-like PF10257.9 KFR01173.1 - 0.00025 20.0 0.2 0.00032 19.7 0.2 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein PH PF00169.29 KFR01174.1 - 9.5e-06 26.1 0.0 1.1e-05 25.9 0.0 1.0 1 0 0 1 1 1 1 PH domain DUF5628 PF18621.1 KFR01174.1 - 0.069 13.6 0.0 0.08 13.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5628) Sharpin_PH PF16764.5 KFR01174.1 - 0.07 12.9 0.0 0.081 12.7 0.0 1.1 1 0 0 1 1 1 0 Sharpin PH domain AbLIM_anchor PF16182.5 KFR01175.1 - 1.8e-59 202.5 10.0 2.6e-59 202.0 10.0 1.3 1 0 0 1 1 1 1 Putative adherens-junction anchoring region of AbLIM VHP PF02209.19 KFR01175.1 - 3.9e-15 55.6 3.0 8e-15 54.6 3.0 1.6 1 0 0 1 1 1 1 Villin headpiece domain FGF PF00167.18 KFR01176.1 - 3.2e-41 140.3 1.2 4.4e-41 139.9 1.2 1.2 1 0 0 1 1 1 1 Fibroblast growth factor TLP1_add_C PF18313.1 KFR01176.1 - 0.017 15.0 0.3 5.1 7.1 0.1 2.3 2 0 0 2 2 2 0 Thiolase-like protein type 1 additional C-terminal domain Fascin PF06268.13 KFR01176.1 - 0.041 14.1 0.1 0.06 13.6 0.1 1.4 1 0 0 1 1 1 0 Fascin domain IL1 PF00340.19 KFR01176.1 - 0.079 12.6 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Interleukin-1 / 18 Polysacc_synt_4 PF04669.13 KFR01177.1 - 1.2e-08 34.7 0.1 1.3e-08 34.6 0.1 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis IBN_N PF03810.19 KFR01178.1 - 3.1e-13 49.5 0.1 3.1e-13 49.5 0.1 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KFR01178.1 - 0.0068 16.5 0.6 0.0068 16.5 0.6 3.7 4 0 0 4 4 4 1 Exportin 1-like protein Rep_fac_C PF08542.11 KFR01178.1 - 3.8 8.0 4.6 15 6.1 0.1 4.1 5 0 0 5 5 5 0 Replication factor C C-terminal domain GDNF PF02351.16 KFR01180.1 - 9.1e-46 154.8 48.0 1.7e-24 86.6 7.3 3.1 3 0 0 3 3 3 3 GDNF/GAS1 domain ATP-synt_ab PF00006.25 KFR01181.1 - 2.7e-68 229.8 0.0 3.9e-68 229.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KFR01181.1 - 4.2e-13 49.6 0.4 1e-12 48.4 0.1 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain DUF2481 PF10654.9 KFR01181.1 - 0.15 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) MFS_1 PF07690.16 KFR01182.1 - 9.5e-40 136.6 46.9 2.8e-32 112.0 36.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily CPP1-like PF11833.8 KFR01182.1 - 1.2 8.7 3.1 3.3 7.3 2.9 1.8 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like LacY_symp PF01306.19 KFR01182.1 - 2.3 6.9 21.2 0.7 8.6 5.9 2.4 2 0 0 2 2 2 0 LacY proton/sugar symporter Ribosomal_L28e PF01778.17 KFR01183.1 - 2.8e-34 118.3 0.1 2.8e-34 118.3 0.1 1.9 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 KFR01183.1 - 5.8e-31 107.1 14.7 5.8e-31 107.1 14.7 2.7 2 1 1 3 3 3 1 Mak16 protein C-terminal region BUD22 PF09073.10 KFR01183.1 - 0.00072 19.0 16.7 0.00091 18.7 16.7 1.1 1 0 0 1 1 1 1 BUD22 DUF2201_N PF13203.6 KFR01183.1 - 0.63 9.6 5.6 0.91 9.1 5.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain SAPS PF04499.15 KFR01183.1 - 2.3 6.9 10.4 2.8 6.6 10.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 KFR01183.1 - 4.6 5.3 7.9 4.6 5.2 7.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Tti2 PF10521.9 KFR01184.1 - 6.2e-10 39.1 1.9 4.6e-09 36.2 1.9 2.3 1 1 0 1 1 1 1 Tti2 family Utp13 PF08625.11 KFR01184.1 - 0.0085 16.0 0.5 3.8 7.4 0.2 3.1 3 0 0 3 3 3 2 Utp13 specific WD40 associated domain F-box PF00646.33 KFR01184.1 - 0.0099 15.7 1.3 0.36 10.8 0.1 2.7 2 0 0 2 2 2 1 F-box domain zf-RING_2 PF13639.6 KFR01185.1 - 5.2e-12 45.9 8.8 5.2e-12 45.9 8.8 1.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KFR01185.1 - 4.1e-11 42.4 1.8 1.1e-10 41.0 1.8 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KFR01185.1 - 7.1e-08 32.2 7.8 1.6e-07 31.0 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFR01185.1 - 9.2e-08 32.0 3.1 9.5e-08 31.9 1.5 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 KFR01185.1 - 1.5e-07 31.6 11.0 1.2e-06 28.7 11.0 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KFR01185.1 - 2.2e-07 30.6 9.4 4.8e-07 29.5 9.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFR01185.1 - 1.6e-05 24.7 7.3 3.1e-05 23.8 7.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFR01185.1 - 5.3e-05 23.0 7.2 5.3e-05 23.0 7.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFR01185.1 - 0.00037 20.5 6.3 0.0011 19.0 6.3 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KFR01185.1 - 0.0046 16.8 7.0 0.009 15.9 7.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 KFR01185.1 - 0.11 12.4 8.2 0.14 12.1 2.8 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3H2C3 PF17122.5 KFR01185.1 - 0.27 11.3 6.6 0.88 9.7 6.6 1.9 1 1 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 KFR01185.1 - 0.38 10.9 9.6 16 5.7 9.6 2.8 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KFR01185.1 - 8.4 6.1 14.7 0.32 10.7 8.3 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type DSPc PF00782.20 KFR01186.1 - 1.7e-29 102.3 0.0 2e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFR01186.1 - 0.00049 19.7 0.0 0.00067 19.3 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase UPA PF17217.3 KFR01187.1 - 1.2e-62 209.9 0.7 1.2e-62 209.9 0.7 2.0 2 0 0 2 2 2 1 UPA domain ZU5 PF00791.20 KFR01187.1 - 3.7e-30 104.1 0.0 8.7e-30 103.0 0.0 1.7 1 0 0 1 1 1 1 ZU5 domain Death PF00531.22 KFR01187.1 - 9e-14 51.4 0.1 1.7e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 Death domain I-set PF07679.16 KFR01187.1 - 2e-12 47.0 0.0 1.8e-11 43.9 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR01187.1 - 2.4e-12 47.3 0.0 5.1e-10 39.8 0.0 2.8 2 0 0 2 2 2 1 Immunoglobulin domain TSP_1 PF00090.19 KFR01187.1 - 4.4e-10 39.6 24.7 4e-07 30.2 10.6 3.0 2 0 0 2 2 2 2 Thrombospondin type 1 domain ig PF00047.25 KFR01187.1 - 1.3e-08 34.9 0.0 9.5e-08 32.1 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFR01187.1 - 7.1e-08 32.7 0.0 3.3e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Ig_6 PF18452.1 KFR01187.1 - 0.017 14.7 0.0 0.045 13.3 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KFR01187.1 - 0.02 15.1 0.0 0.21 11.8 0.0 2.6 1 1 0 1 1 1 0 Immunoglobulin V-set domain RVT_1 PF00078.27 KFR01188.1 - 0.031 13.8 0.0 0.036 13.6 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Band_7 PF01145.25 KFR01189.1 - 1.5e-09 38.1 0.8 1.5e-09 38.1 0.8 1.7 1 1 1 2 2 2 1 SPFH domain / Band 7 family DUF4346 PF14251.6 KFR01189.1 - 0.03 14.4 1.4 0.065 13.3 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4346) RapA_C PF12137.8 KFR01189.1 - 0.059 12.4 5.6 0.11 11.5 5.6 1.5 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal Ala_racemase_N PF01168.20 KFR01190.1 - 5.4e-19 68.7 0.0 6.9e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain LRR_8 PF13855.6 KFR01191.1 - 1.5e-23 82.3 8.7 1.3e-13 50.5 2.2 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFR01191.1 - 4.7e-10 39.6 7.8 2.6e-07 30.8 1.5 3.5 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) GPS PF01825.21 KFR01191.1 - 8.5e-10 39.0 0.4 3.4e-09 37.1 0.0 2.3 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif I-set PF07679.16 KFR01191.1 - 2.5e-07 30.7 0.1 6.1e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain 7tm_2 PF00002.24 KFR01191.1 - 1.8e-06 27.4 7.1 3.8e-06 26.4 7.1 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Ig_2 PF13895.6 KFR01191.1 - 3.9e-06 27.1 1.3 1.5e-05 25.2 0.1 2.7 3 0 0 3 3 3 1 Immunoglobulin domain Ig_3 PF13927.6 KFR01191.1 - 8.3e-06 26.3 0.5 4.2e-05 24.1 0.1 2.6 3 0 0 3 3 2 1 Immunoglobulin domain HRM PF02793.22 KFR01191.1 - 3.6e-05 24.0 1.1 8.7e-05 22.7 1.1 1.7 1 0 0 1 1 1 1 Hormone receptor domain LRR_1 PF00560.33 KFR01191.1 - 0.00047 20.3 4.3 0.14 12.8 0.2 3.7 3 0 0 3 3 2 2 Leucine Rich Repeat ig PF00047.25 KFR01191.1 - 0.0024 18.0 0.8 0.0062 16.7 0.2 2.0 2 0 0 2 2 2 1 Immunoglobulin domain TPKR_C2 PF16920.5 KFR01191.1 - 0.023 14.8 0.4 1.1 9.5 0.3 3.0 2 0 0 2 2 2 0 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_9 PF14580.6 KFR01191.1 - 0.18 11.3 0.1 0.3 10.6 0.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeat RBD-FIP PF09457.10 KFR01192.1 - 3.1e-16 59.0 2.6 6.5e-16 58.0 2.6 1.6 1 0 0 1 1 1 1 FIP domain Nucleoplasmin PF03066.15 KFR01194.1 - 9.2e-10 38.9 0.4 1.5e-09 38.3 0.1 1.5 1 1 0 1 1 1 1 Nucleoplasmin/nucleophosmin domain eIF_4EBP PF05456.11 KFR01195.1 - 5.3e-24 84.4 0.0 5.8e-24 84.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) TGF_beta PF00019.20 KFR01196.1 - 1.2e-29 103.3 1.1 2.3e-29 102.4 1.1 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFR01196.1 - 6.5e-06 26.1 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 TGF-beta propeptide SPRY PF00622.28 KFR01197.1 - 2.1e-11 44.0 0.2 0.00013 22.1 0.0 2.4 2 0 0 2 2 2 2 SPRY domain START PF01852.19 KFR01198.1 - 4.9e-47 160.0 0.0 5.9e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 START domain Polyketide_cyc PF03364.20 KFR01198.1 - 0.0023 18.1 0.0 0.022 15.0 0.0 2.4 2 1 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KFR01198.1 - 0.12 12.6 0.0 1.1 9.5 0.0 2.5 2 1 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport Pkinase PF00069.25 KFR01199.1 - 2.5e-63 213.9 0.0 2.9e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR01199.1 - 2.5e-33 115.4 0.0 3.1e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR01199.1 - 1.9e-06 27.4 0.0 2.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFR01199.1 - 1.2e-05 24.3 0.0 2.5e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 KFR01199.1 - 0.038 13.6 0.1 0.65 9.6 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFR01199.1 - 0.043 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3824 PF12868.7 KFR01199.1 - 1.9 9.2 3.5 10 6.8 0.3 2.1 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) LSM PF01423.22 KFR01200.1 - 2e-14 53.0 0.2 3.7e-14 52.2 0.2 1.5 1 0 0 1 1 1 1 LSM domain DUF658 PF04936.12 KFR01200.1 - 0.079 12.7 0.1 0.1 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF658) DDHD PF02862.17 KFR01201.1 - 3.5e-53 181.1 0.0 8.1e-53 179.9 0.0 1.6 2 0 0 2 2 2 1 DDHD domain WWE PF02825.20 KFR01201.1 - 5.5e-14 52.5 5.1 6.3e-09 36.3 0.4 2.9 2 0 0 2 2 2 2 WWE domain SAM_1 PF00536.30 KFR01201.1 - 5.3e-13 49.2 0.0 1e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFR01201.1 - 1.4e-05 25.1 0.0 3.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PAP2 PF01569.21 KFR01202.1 - 3.6e-31 107.7 1.3 3.6e-31 107.7 1.3 1.4 2 0 0 2 2 2 1 PAP2 superfamily Strabismus PF06638.11 KFR01202.1 - 0.016 13.9 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 Strabismus protein PAP2_C PF14360.6 KFR01202.1 - 0.017 15.7 0.2 0.039 14.5 0.2 1.5 1 0 0 1 1 1 0 PAP2 superfamily C-terminal PAP2_3 PF14378.6 KFR01202.1 - 0.035 13.8 4.4 0.42 10.3 4.4 2.3 1 1 0 1 1 1 0 PAP2 superfamily Virul_fac_BrkB PF03631.15 KFR01202.1 - 0.074 12.7 2.6 5.7 6.5 0.0 2.1 2 0 0 2 2 2 0 Virulence factor BrkB DUF4231 PF14015.6 KFR01202.1 - 0.18 12.3 0.0 0.34 11.4 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) RseC_MucC PF04246.12 KFR01202.1 - 0.23 11.4 1.4 16 5.4 0.1 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF5389 PF17364.2 KFR01202.1 - 0.39 10.8 0.1 0.39 10.8 0.1 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5389) YhhN PF07947.14 KFR01202.1 - 1.9 8.0 7.1 2.2 7.8 3.3 2.4 2 1 0 2 2 2 0 YhhN family C5HCH PF17982.1 KFR01203.1 - 6.3e-24 83.9 13.3 6.3e-24 83.9 13.3 5.0 4 1 0 4 4 4 1 NSD Cys-His rich domain SET PF00856.28 KFR01203.1 - 3.1e-21 76.5 0.6 4.5e-20 72.7 0.4 2.9 3 1 0 3 3 3 1 SET domain AWS PF17907.1 KFR01203.1 - 3.3e-17 62.2 8.5 3.3e-17 62.2 8.5 5.2 5 0 0 5 5 5 1 AWS domain PWWP PF00855.17 KFR01203.1 - 8.2e-14 51.8 0.4 8.2e-14 51.8 0.4 2.7 2 1 0 2 2 2 1 PWWP domain PHD PF00628.29 KFR01203.1 - 3.8e-12 45.9 74.3 4.5e-05 23.3 7.1 6.7 4 2 2 6 6 6 4 PHD-finger zf-HC5HC2H_2 PF13832.6 KFR01203.1 - 0.00015 21.9 3.5 0.00015 21.9 3.5 6.3 3 2 2 7 7 7 1 PHD-zinc-finger like domain LETM1 PF07766.13 KFR01204.1 - 2.2e-104 348.6 8.6 2.6e-104 348.3 8.6 1.1 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.27 KFR01204.1 - 0.0071 16.1 1.7 0.026 14.3 0.4 2.7 2 1 0 2 2 2 1 SAP domain Pkinase_Tyr PF07714.17 KFR01205.1 - 5e-105 350.5 0.0 7.4e-105 349.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR01205.1 - 1.6e-45 155.6 0.0 2.5e-45 154.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.16 KFR01205.1 - 2e-37 127.2 0.0 6.7e-14 51.7 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR01205.1 - 4e-32 110.6 0.2 4.5e-12 46.4 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFR01205.1 - 5.6e-31 106.6 0.1 5.8e-09 36.0 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFR01205.1 - 1.5e-24 86.2 0.3 3.8e-10 40.0 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin domain FGFR3_TM PF18123.1 KFR01205.1 - 2.3e-14 52.6 4.0 3.8e-14 51.9 4.0 1.4 1 0 0 1 1 1 1 Fibroblast growth factor receptor 3 transmembrane domain V-set PF07686.17 KFR01205.1 - 2.8e-14 53.2 2.9 3.1e-05 24.1 0.0 5.2 3 3 0 3 3 3 3 Immunoglobulin V-set domain Ig_5 PF16681.5 KFR01205.1 - 9.5e-09 35.5 0.1 0.027 14.9 0.0 4.1 3 1 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFR01205.1 - 4.9e-06 26.7 0.0 0.0047 17.1 0.0 3.7 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFR01205.1 - 1.7e-05 24.3 0.1 0.21 11.2 0.0 3.5 3 0 0 3 3 3 1 Immunoglobulin domain C2-set_2 PF08205.12 KFR01205.1 - 0.00059 19.9 0.1 0.48 10.5 0.0 3.4 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFR01205.1 - 0.045 13.8 0.0 22 5.2 0.0 3.4 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain DUF2890 PF11081.8 KFR01205.1 - 0.059 13.5 0.6 0.12 12.5 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) V-set_CD47 PF08204.11 KFR01205.1 - 0.096 12.7 0.1 1 9.3 0.0 2.6 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain DUF4396 PF14342.6 KFR01205.1 - 0.098 13.0 0.8 0.16 12.3 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) Pkinase_fungal PF17667.1 KFR01205.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF1615 PF07759.12 KFR01205.1 - 0.19 10.9 0.0 0.35 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1615) TACC_C PF05010.14 KFR01206.1 - 6.6e-81 270.9 35.4 1e-80 270.3 35.4 1.3 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal ADIP PF11559.8 KFR01206.1 - 1.2 9.2 26.1 0.67 10.0 12.4 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding PI3K_P85_iSH2 PF16454.5 KFR01206.1 - 1.9 8.0 29.4 28 4.3 29.4 2.2 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Methyltrn_RNA_4 PF09936.9 KFR01206.1 - 4.8 7.0 10.6 11 5.9 0.9 2.3 2 0 0 2 2 2 0 SAM-dependent RNA methyltransferase CENP-F_leu_zip PF10473.9 KFR01206.1 - 7.1 6.7 32.1 9.2 6.3 21.7 2.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 KFR01206.1 - 8.8 5.6 33.9 92 2.3 33.7 2.2 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding PH PF00169.29 KFR01207.1 - 5.4e-18 65.4 0.7 2.4e-10 40.9 0.0 2.2 2 0 0 2 2 2 2 PH domain PH_8 PF15409.6 KFR01207.1 - 1.1e-07 32.1 2.3 0.00034 20.9 0.1 2.9 2 1 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 KFR01207.1 - 2.7e-07 31.0 0.4 0.004 17.5 0.4 2.4 2 1 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.7 KFR01207.1 - 4.5e-05 23.5 0.0 7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.6 KFR01207.1 - 0.00064 20.1 0.1 0.0019 18.5 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain IDO PF01231.18 KFR01208.1 - 1.7e-116 389.6 0.0 2.1e-116 389.3 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 KFR01208.1 - 0.0095 14.7 0.1 0.071 11.8 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1864) TC1 PF15063.6 KFR01209.1 - 5.5e-36 122.3 0.2 6.8e-36 122.0 0.2 1.1 1 0 0 1 1 1 1 Thyroid cancer protein 1 tRNA_bind_2 PF13725.6 KFR01209.1 - 0.0058 16.4 1.2 0.0068 16.1 1.2 1.1 1 0 0 1 1 1 1 Possible tRNA binding domain MRP-S22 PF10245.9 KFR01209.1 - 0.022 14.5 1.4 0.026 14.3 1.4 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S22 MgtE_N PF03448.17 KFR01209.1 - 0.05 14.2 1.2 0.46 11.1 1.2 2.0 1 1 0 1 1 1 0 MgtE intracellular N domain zf-met PF12874.7 KFR01210.1 - 1e-22 79.7 20.6 5.1e-08 33.0 2.2 3.2 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFR01210.1 - 1.4e-16 60.3 12.5 1.8e-05 24.9 0.6 3.2 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFR01210.1 - 1.1e-05 25.7 12.3 0.072 13.4 0.8 3.1 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.12 KFR01210.1 - 0.0003 20.5 11.5 0.0095 15.7 0.5 3.2 3 0 0 3 3 3 2 U1 zinc finger CTU2 PF10288.9 KFR01210.1 - 0.0016 18.7 7.2 0.16 12.2 0.6 3.0 2 1 1 3 3 3 2 Cytoplasmic tRNA 2-thiolation protein 2 zf-C2H2_4 PF13894.6 KFR01210.1 - 0.002 18.8 10.0 0.22 12.4 0.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger DUF3449 PF11931.8 KFR01210.1 - 0.014 15.2 7.9 0.087 12.6 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3449) zf-C2H2_3 PF13878.6 KFR01210.1 - 0.018 14.8 4.9 4.2 7.3 0.4 3.4 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO zf-C2H2 PF00096.26 KFR01210.1 - 0.055 14.0 12.1 0.61 10.6 0.6 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFR01210.1 - 0.098 12.7 10.9 1.6 8.8 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Endonuclease_7 PF02945.15 KFR01210.1 - 2.1 8.3 8.8 4.9 7.1 3.4 2.7 1 1 1 2 2 2 0 Recombination endonuclease VII Erf4 PF10256.9 KFR01211.1 - 4.3e-25 88.1 0.0 4.8e-25 87.9 0.0 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family SLD5_C PF16922.5 KFR01212.1 - 1.8e-18 66.5 0.0 3e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KFR01212.1 - 8.1e-06 26.3 0.5 1.5e-05 25.4 0.3 1.6 1 1 0 2 2 2 1 GINS complex protein HipN PF18253.1 KFR01212.1 - 0.024 14.3 1.3 0.066 12.9 0.0 2.4 4 0 0 4 4 4 0 Hsp70-interacting protein N N-terminal domain Acyltransferase PF01553.21 KFR01213.1 - 2.1e-19 69.5 0.1 4.5e-19 68.4 0.1 1.6 1 0 0 1 1 1 1 Acyltransferase Topo_C_assoc PF14370.6 KFR01213.1 - 0.11 12.4 0.1 0.47 10.4 0.0 2.1 2 0 0 2 2 2 0 C-terminal topoisomerase domain UPA_2 PF17809.1 KFR01214.1 - 1.9e-07 31.0 0.1 2.5e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 UPA domain Adap_comp_sub PF00928.21 KFR01215.1 - 4.8e-75 252.3 0.0 5.9e-75 252.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFR01215.1 - 4e-05 23.6 0.7 7.3e-05 22.7 0.7 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Trypsin PF00089.26 KFR01216.1 - 2.6e-68 230.1 0.0 4.2e-68 229.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin Kringle PF00051.18 KFR01216.1 - 2.1e-44 149.7 28.2 9.1e-23 80.4 5.4 3.2 3 0 0 3 3 3 2 Kringle domain Trypsin_2 PF13365.6 KFR01216.1 - 9.1e-06 26.6 0.0 1.8e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain EGF PF00008.27 KFR01216.1 - 0.0015 18.8 8.6 0.0015 18.8 8.6 4.3 5 0 0 5 5 5 1 EGF-like domain DUF1986 PF09342.11 KFR01216.1 - 0.027 14.8 0.0 0.055 13.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) IKBKB_SDD PF18397.1 KFR01217.1 - 1.1e-132 441.4 16.6 2e-132 440.6 16.6 1.4 1 0 0 1 1 1 1 IQBAL scaffold dimerization domain Pkinase PF00069.25 KFR01217.1 - 3.5e-40 138.1 0.0 8.6e-40 136.8 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR01217.1 - 1.4e-26 93.3 0.0 4.1e-26 91.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase IKKbetaNEMObind PF12179.8 KFR01217.1 - 4.3e-15 55.4 8.8 4.3e-15 55.4 8.8 2.7 2 0 0 2 2 2 1 I-kappa-kinase-beta NEMO binding domain Pkinase_fungal PF17667.1 KFR01217.1 - 1.6e-07 30.5 0.0 3.4e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFR01217.1 - 0.00013 21.4 0.0 0.00031 20.2 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ubiquitin PF00240.23 KFR01217.1 - 0.00019 21.1 0.1 0.00069 19.3 0.1 2.0 1 0 0 1 1 1 1 Ubiquitin family APH PF01636.23 KFR01217.1 - 0.0014 18.6 0.4 0.0063 16.5 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KFR01217.1 - 0.0091 15.5 0.0 0.038 13.5 0.0 2.0 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL TBK1_ULD PF18396.1 KFR01217.1 - 0.04 13.9 0.2 0.11 12.4 0.2 1.7 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Porin_3 PF01459.22 KFR01218.1 - 9.1e-70 235.2 7.8 1e-69 235.0 7.8 1.0 1 0 0 1 1 1 1 Eukaryotic porin RNA_pol_3_Rpc31 PF11705.8 KFR01225.1 - 7.3e-33 114.7 24.8 8.8e-33 114.5 24.8 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 ALMT PF11744.8 KFR01225.1 - 0.54 9.0 4.9 0.67 8.7 4.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF5094 PF17015.5 KFR01225.1 - 0.84 9.7 14.5 1.5 8.9 14.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) PA26 PF04636.13 KFR01225.1 - 2 7.2 7.7 2.6 6.9 7.7 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Protocadherin PF08374.11 KFR01225.1 - 3.4 7.6 9.4 4.7 7.1 9.4 1.2 1 0 0 1 1 1 0 Protocadherin Rgp1 PF08737.10 KFR01225.1 - 3.6 6.7 7.1 4 6.5 7.1 1.1 1 0 0 1 1 1 0 Rgp1 Neur_chan_memb PF02932.16 KFR01225.1 - 4.2 7.4 5.5 5 7.1 5.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PI3K_1B_p101 PF10486.9 KFR01225.1 - 6.2 4.5 10.7 7.8 4.1 10.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF913 PF06025.12 KFR01225.1 - 8 5.3 7.7 11 4.9 7.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NOA36 PF06524.12 KFR01225.1 - 8.4 5.6 16.2 12 5.1 16.2 1.3 1 0 0 1 1 1 0 NOA36 protein SAPS PF04499.15 KFR01225.1 - 8.8 5.0 12.2 10 4.7 12.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein LysM PF01476.20 KFR01226.1 - 1.1e-06 28.6 0.1 2.7e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 LysM domain YqhR PF11085.8 KFR01226.1 - 0.039 13.9 0.2 0.056 13.4 0.2 1.2 1 0 0 1 1 1 0 Conserved membrane protein YqhR DUF4199 PF13858.6 KFR01226.1 - 0.14 12.5 0.0 0.21 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Arrestin_C PF02752.22 KFR01227.1 - 2.3e-23 83.1 0.0 3.6e-21 76.0 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KFR01227.1 - 1.3e-18 67.5 0.0 7.5e-17 61.7 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain CH PF00307.31 KFR01249.1 - 4e-21 75.2 0.0 6.6e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFR01249.1 - 0.00048 19.9 0.0 0.00082 19.2 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain F-box-like PF12937.7 KFR01250.1 - 1.1e-07 31.7 2.6 1.1e-07 31.7 2.6 3.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KFR01250.1 - 8.2e-06 25.6 1.9 8.2e-06 25.6 1.9 3.3 5 0 0 5 5 5 1 F-box domain F-box_5 PF18511.1 KFR01250.1 - 0.00086 18.8 0.7 0.0019 17.7 0.7 1.5 1 0 0 1 1 1 1 F-box RCS1 PF07326.11 KFR01251.1 - 1.8e-55 188.4 8.3 2e-55 188.3 8.3 1.0 1 0 0 1 1 1 1 Regulator of chromosome segregation 1 RCS1 PF07326.11 KFR01252.1 - 5.4e-25 88.7 0.5 5.9e-25 88.6 0.5 1.0 1 0 0 1 1 1 1 Regulator of chromosome segregation 1 DDHD PF02862.17 KFR01253.1 - 3.3e-51 174.6 0.0 9.8e-51 173.0 0.0 1.9 1 0 0 1 1 1 1 DDHD domain Acid_phosphat_B PF03767.14 KFR01253.1 - 0.012 15.2 0.0 0.035 13.7 0.0 1.7 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) LNS2 PF08235.13 KFR01253.1 - 0.043 13.3 0.1 0.22 10.9 0.1 2.0 1 1 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) DUF953 PF06110.11 KFR01254.1 - 6.9e-43 145.1 0.0 7.8e-43 144.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.20 KFR01254.1 - 0.12 12.4 0.1 0.91 9.5 0.1 2.2 2 1 0 2 2 2 0 Thioredoxin Thioredoxin_9 PF14595.6 KFR01254.1 - 0.14 11.9 0.1 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin Med31 PF05669.12 KFR01255.1 - 1e-40 137.6 11.2 1.6e-40 137.0 11.2 1.2 1 0 0 1 1 1 1 SOH1 IL8 PF00048.20 KFR01256.1 - 5.6e-05 23.2 0.7 6.9e-05 22.9 0.7 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like IL8 PF00048.20 KFR01257.1 - 8.3e-12 45.1 0.6 1e-11 44.8 0.6 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like IL8 PF00048.20 KFR01258.1 - 9.2e-14 51.3 3.4 1e-13 51.2 3.4 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like TMEM132 PF16070.5 KFR01259.1 - 2.9e-139 464.2 3.0 3.6e-139 463.9 3.0 1.1 1 0 0 1 1 1 1 Transmembrane protein family 132 TMEM132D_C PF15706.5 KFR01259.1 - 1.7e-32 111.0 0.0 3.3e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Pinin_SDK_N PF04697.13 KFR01259.1 - 0.23 12.1 1.0 11 6.7 0.0 2.4 2 0 0 2 2 2 0 pinin/SDK conserved region DUF1168 PF06658.12 KFR01260.1 - 0.078 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) UNC45-central PF11701.8 KFR01261.1 - 1.6e-35 122.3 9.5 2.3e-35 121.8 0.1 4.3 5 1 1 6 6 6 1 Myosin-binding striated muscle assembly central TPR_1 PF00515.28 KFR01261.1 - 3.5e-13 48.8 9.1 5.9e-05 22.7 0.5 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFR01261.1 - 1.4e-11 43.5 7.7 0.0015 18.5 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat HEAT_2 PF13646.6 KFR01261.1 - 1.3e-08 35.1 2.3 1.2 9.6 0.0 5.8 5 1 1 6 6 5 2 HEAT repeats Arm PF00514.23 KFR01261.1 - 5.8e-08 32.5 9.0 0.012 15.6 0.1 6.4 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat TPR_11 PF13414.6 KFR01261.1 - 1.8e-07 30.7 3.6 1.8e-05 24.3 1.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 KFR01261.1 - 1.2e-06 28.3 7.9 0.003 17.6 0.1 3.4 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFR01261.1 - 2.1e-05 25.0 3.6 4.1e-05 24.1 1.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFR01261.1 - 0.00026 21.2 4.1 0.0079 16.5 1.0 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFR01261.1 - 0.00076 19.7 2.1 0.86 10.1 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFR01261.1 - 0.0071 17.1 0.6 2.4 9.2 0.1 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFR01261.1 - 0.02 15.1 5.1 0.12 12.6 4.9 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KFR01261.1 - 0.022 15.4 2.3 2.3 9.0 0.2 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFR01261.1 - 0.054 13.6 0.2 0.92 9.7 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF3856 PF12968.7 KFR01261.1 - 0.094 12.8 0.7 4.7 7.3 0.7 3.0 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_7 PF13176.6 KFR01261.1 - 0.1 12.7 0.9 0.34 11.0 0.1 2.4 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFR01261.1 - 0.32 11.5 6.3 1.6 9.3 0.9 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat HEAT_EZ PF13513.6 KFR01261.1 - 1.1 9.9 6.2 11 6.6 0.1 4.9 5 0 0 5 5 5 0 HEAT-like repeat V-ATPase_H_C PF11698.8 KFR01261.1 - 7.4 6.7 7.3 64 3.7 0.1 4.6 5 1 1 6 6 5 0 V-ATPase subunit H AlbA_2 PF04326.14 KFR01262.1 - 3.4e-14 53.2 0.3 3.4e-10 40.3 0.0 2.5 2 0 0 2 2 2 2 Putative DNA-binding domain DUF2075 PF09848.9 KFR01262.1 - 1.4e-06 27.8 0.1 7.5e-06 25.4 0.1 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KFR01262.1 - 0.00045 20.5 0.7 0.032 14.5 0.7 2.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 KFR01262.1 - 0.0009 18.8 1.1 0.093 12.2 0.2 2.3 1 1 1 2 2 2 1 PhoH-like protein AAA_14 PF13173.6 KFR01262.1 - 0.001 19.1 0.0 0.0031 17.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFR01262.1 - 0.0033 17.8 0.3 0.12 12.7 0.3 2.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KFR01262.1 - 0.0042 17.5 0.0 0.011 16.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 KFR01262.1 - 0.0045 17.0 0.4 0.025 14.6 0.1 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit B3R PF17057.5 KFR01262.1 - 0.0085 16.3 0.0 0.024 14.8 0.0 1.8 1 0 0 1 1 1 1 Poxviridae B3 protein AAA_24 PF13479.6 KFR01262.1 - 0.016 14.9 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFR01262.1 - 0.018 15.6 0.0 0.17 12.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 KFR01262.1 - 0.033 13.4 1.9 0.13 11.4 0.0 2.6 4 0 0 4 4 4 0 PIF1-like helicase DEAD PF00270.29 KFR01262.1 - 0.036 13.8 0.3 2.9 7.6 0.0 2.6 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_11 PF13086.6 KFR01262.1 - 0.044 13.6 0.2 0.14 12.0 0.1 1.8 1 1 1 2 2 2 0 AAA domain ATPase PF06745.13 KFR01262.1 - 0.053 12.9 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 KaiC UvrD_C_2 PF13538.6 KFR01262.1 - 0.088 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain NB-ARC PF00931.22 KFR01262.1 - 0.092 11.9 0.0 0.35 10.0 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 KFR01262.1 - 0.11 12.7 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFR01262.1 - 0.15 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFR01262.1 - 0.21 12.0 0.2 2.2 8.6 0.2 2.2 1 1 0 1 1 1 0 AAA ATPase domain Pex2_Pex12 PF04757.14 KFR01263.1 - 6.4e-50 169.8 4.5 7.8e-50 169.6 4.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 KFR01263.1 - 0.00012 21.8 2.1 0.00021 21.1 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFR01263.1 - 0.00073 19.3 1.1 0.0015 18.3 1.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFR01263.1 - 0.024 14.5 1.3 0.044 13.7 1.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) EKLF_TAD1 PF16832.5 KFR01263.1 - 0.048 13.5 0.2 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 zf-RING_5 PF14634.6 KFR01263.1 - 0.08 12.9 0.5 4.4 7.4 0.1 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 KFR01263.1 - 0.085 13.2 5.3 0.45 10.9 5.4 2.0 1 1 1 2 2 2 0 Ring finger domain Prok-RING_4 PF14447.6 KFR01263.1 - 1.1 9.2 2.9 35 4.4 0.3 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFR01263.1 - 2.8 8.3 4.1 37 4.7 4.1 2.3 1 1 0 1 1 1 0 RING-H2 zinc finger domain Adaptin_N PF01602.20 KFR01264.1 - 3.4e-157 524.2 13.0 4.3e-157 523.8 13.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KFR01264.1 - 2.9e-67 225.7 12.7 2.4e-66 222.8 1.5 3.8 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 KFR01264.1 - 1.1e-37 128.6 0.1 3.2e-37 127.0 0.1 1.9 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 KFR01264.1 - 3.1e-22 78.8 5.2 2.4e-06 27.8 0.1 6.5 3 2 4 7 7 7 5 HEAT repeats HEAT PF02985.22 KFR01264.1 - 4.8e-13 48.2 8.8 0.0081 16.3 0.1 7.6 7 0 0 7 7 7 3 HEAT repeat Alpha_adaptinC2 PF02883.20 KFR01264.1 - 9.5e-13 48.4 0.4 2e-12 47.4 0.4 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Arm PF00514.23 KFR01264.1 - 4.9e-08 32.8 2.2 0.027 14.5 0.0 5.4 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Cnd3 PF12719.7 KFR01264.1 - 6.4e-06 25.6 3.8 0.00052 19.3 0.2 2.8 2 1 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 KFR01264.1 - 0.00016 21.3 2.3 0.74 9.3 0.1 4.0 2 2 2 4 4 4 2 CLASP N terminal RTP1_C1 PF10363.9 KFR01264.1 - 0.00022 21.4 4.8 0.68 10.1 0.0 5.1 1 1 2 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 TIP120 PF08623.10 KFR01264.1 - 0.00022 21.0 4.7 1 9.1 0.0 4.5 4 1 0 4 4 4 1 TATA-binding protein interacting (TIP20) Arm_2 PF04826.13 KFR01264.1 - 0.0019 17.7 1.2 0.04 13.4 0.2 2.6 1 1 1 2 2 2 1 Armadillo-like Sec7_N PF12783.7 KFR01264.1 - 0.012 15.5 7.2 0.023 14.6 0.2 4.2 5 1 1 6 6 6 0 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT_EZ PF13513.6 KFR01264.1 - 0.03 14.8 7.1 12 6.5 0.0 5.9 7 0 0 7 7 6 0 HEAT-like repeat MOR2-PAG1_C PF14225.6 KFR01264.1 - 0.11 12.3 0.9 0.35 10.7 0.1 2.1 2 1 1 3 3 3 0 Cell morphogenesis C-terminal Ras PF00071.22 KFR01265.1 - 3.3e-25 88.6 0.0 6.4e-25 87.6 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFR01265.1 - 4.4e-08 33.4 0.0 4.1e-07 30.2 0.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR01265.1 - 0.00066 19.2 0.0 0.011 15.2 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFR01265.1 - 0.0025 17.9 0.0 0.0035 17.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFR01265.1 - 0.022 15.1 0.0 0.043 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 KFR01265.1 - 0.051 13.8 0.0 0.082 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain GAS2 PF02187.17 KFR01266.1 - 4.8e-33 113.1 0.2 8.1e-33 112.3 0.2 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.31 KFR01266.1 - 5.1e-15 55.6 0.1 9.9e-15 54.7 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain RRM_1 PF00076.22 KFR01267.1 - 7.7e-13 48.1 0.1 4e-12 45.8 0.1 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 KFR01267.1 - 2.6e-08 33.0 5.9 4e-08 32.4 5.9 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Rhomboid PF01694.22 KFR01268.1 - 2.1e-15 57.0 7.7 2.6e-15 56.7 7.7 1.1 1 0 0 1 1 1 1 Rhomboid family DER1 PF04511.15 KFR01268.1 - 0.0066 16.4 1.6 0.012 15.5 1.6 1.6 1 1 0 1 1 1 1 Der1-like family DUF2306 PF10067.9 KFR01268.1 - 0.12 12.6 4.5 0.17 12.1 4.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) TssN PF17555.2 KFR01268.1 - 2.5 7.4 5.8 0.66 9.3 2.8 1.5 1 1 1 2 2 2 0 Type VI secretion system, TssN FAD_binding_1 PF00667.20 KFR01269.1 - 1.6e-81 273.1 0.0 2.6e-81 272.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFR01269.1 - 4.6e-40 137.1 0.2 1.6e-39 135.4 0.3 1.9 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 KFR01269.1 - 1.2e-13 51.6 0.0 7.1e-13 49.2 0.0 2.3 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain TMPIT PF07851.13 KFR01270.1 - 2.4e-152 506.8 17.4 2.8e-152 506.6 17.4 1.0 1 0 0 1 1 1 1 TMPIT-like protein DSPc PF00782.20 KFR01271.1 - 4.6e-14 52.4 0.1 2e-13 50.3 0.1 1.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 KFR01271.1 - 1.5e-05 25.5 0.0 0.00057 20.4 0.0 2.4 1 1 0 1 1 1 1 Rhodanese-like domain Ldh_1_C PF02866.18 KFR01272.1 - 7.1e-57 192.0 0.0 2.1e-56 190.4 0.0 1.8 3 0 0 3 3 3 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KFR01272.1 - 4.1e-48 163.1 0.0 6.1e-48 162.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KFR01272.1 - 0.0022 17.1 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KFR01272.1 - 0.0024 18.3 0.0 0.018 15.5 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KFR01272.1 - 0.044 13.1 0.1 0.26 10.6 0.1 2.2 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SRRM_C PF15230.6 KFR01273.1 - 2.1e-23 82.7 24.3 2.1e-23 82.7 24.3 9.3 3 2 5 8 8 8 1 Serine/arginine repetitive matrix protein C-terminus cwf21 PF08312.12 KFR01273.1 - 2.1e-15 56.6 7.4 4e-15 55.7 7.4 1.5 1 0 0 1 1 1 1 cwf21 domain 14-3-3 PF00244.20 KFR01274.1 - 5.1e-96 320.5 7.1 5.7e-96 320.3 7.1 1.0 1 0 0 1 1 1 1 14-3-3 protein Peptidase_C98 PF15499.6 KFR01274.1 - 0.072 12.5 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase FlaC_arch PF05377.11 KFR01274.1 - 0.14 12.5 0.8 0.34 11.3 0.8 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DTC PF18102.1 KFR01275.1 - 2.1e-61 205.9 0.0 3.5e-61 205.2 0.0 1.4 1 0 0 1 1 1 1 Deltex C-terminal domain WWE PF02825.20 KFR01275.1 - 3.8e-34 117.1 0.8 1.4e-16 60.9 0.0 2.4 2 0 0 2 2 2 2 WWE domain zf-C3HC4 PF00097.25 KFR01275.1 - 3.5e-05 23.6 8.6 0.0001 22.1 8.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFR01275.1 - 0.0016 18.4 4.8 0.0046 16.9 4.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KFR01275.1 - 0.0021 18.3 5.7 0.0059 16.9 5.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFR01275.1 - 0.0027 17.7 1.8 0.012 15.6 1.8 2.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UDP PF14569.6 KFR01275.1 - 0.0045 17.1 1.5 0.012 15.7 1.5 1.7 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-RING_5 PF14634.6 KFR01275.1 - 0.015 15.2 6.2 0.015 15.2 6.2 2.2 2 1 0 2 2 2 0 zinc-RING finger domain zf-RING_11 PF17123.5 KFR01275.1 - 0.025 14.3 6.6 0.36 10.6 2.3 2.7 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_2 PF13639.6 KFR01275.1 - 0.16 12.4 15.9 0.039 14.3 8.7 3.0 2 1 0 2 2 1 0 Ring finger domain PHD PF00628.29 KFR01275.1 - 2.3 8.2 8.1 0.45 10.5 3.3 2.4 2 0 0 2 2 2 0 PHD-finger zf-RING_4 PF14570.6 KFR01275.1 - 8.1 6.3 7.4 1.6 8.6 0.3 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain CRCB PF02537.15 KFR01276.1 - 0.16 12.3 1.8 0.21 11.9 0.1 1.9 2 0 0 2 2 2 0 CrcB-like protein, Camphor Resistance (CrcB) RNA_pol_L_2 PF13656.6 KFR01277.1 - 1.2e-29 101.9 0.1 1.5e-29 101.5 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KFR01277.1 - 1.3e-10 40.5 0.0 1.8e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SHNi-TPR PF10516.9 KFR01277.1 - 0.12 11.9 0.1 0.39 10.2 0.0 1.8 1 1 1 2 2 2 0 SHNi-TPR LRR_4 PF12799.7 KFR01278.1 - 1.8e-07 31.3 6.7 1.8e-07 31.3 6.7 2.9 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFR01278.1 - 9.4e-06 25.3 9.3 0.0017 18.1 2.7 2.8 1 1 0 2 2 2 2 Leucine rich repeat WD40 PF00400.32 KFR01278.1 - 0.0011 19.7 0.3 0.018 15.9 0.0 3.2 2 0 0 2 2 2 1 WD domain, G-beta repeat LRR_9 PF14580.6 KFR01278.1 - 0.051 13.1 2.8 0.089 12.3 2.8 1.3 1 0 0 1 1 1 0 Leucine-rich repeat PQQ_2 PF13360.6 KFR01278.1 - 0.06 12.9 0.0 9 5.8 0.1 2.4 2 0 0 2 2 2 0 PQQ-like domain LRR_1 PF00560.33 KFR01278.1 - 1 10.2 6.9 4.9 8.1 0.5 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat 2OG-FeII_Oxy_2 PF13532.6 KFR01279.1 - 5.1e-05 23.6 0.0 7e-05 23.1 0.0 1.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KFR01279.1 - 0.016 15.7 0.0 0.025 15.0 0.0 1.4 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Orai-1 PF07856.12 KFR01280.1 - 1.5e-71 239.6 7.3 1.9e-71 239.4 7.3 1.1 1 0 0 1 1 1 1 Mediator of CRAC channel activity CopD PF05425.13 KFR01280.1 - 0.0075 16.7 2.5 0.14 12.5 0.0 2.3 1 1 1 2 2 2 1 Copper resistance protein D DUF1980 PF09323.10 KFR01280.1 - 0.059 13.3 0.4 0.059 13.3 0.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) DUF2207 PF09972.9 KFR01280.1 - 0.093 11.5 1.0 0.15 10.8 1.0 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1168 PF06658.12 KFR01281.1 - 4.6e-47 159.2 22.9 5.4e-47 159.0 22.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Caldesmon PF02029.15 KFR01281.1 - 0.012 14.4 24.0 0.014 14.2 24.0 1.0 1 0 0 1 1 1 0 Caldesmon BPL_N PF09825.9 KFR01281.1 - 0.11 11.6 8.6 0.14 11.2 8.6 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Spem1 PF15670.5 KFR01281.1 - 0.15 11.6 8.6 0.21 11.2 8.6 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 FAM60A PF15396.6 KFR01281.1 - 0.17 11.8 11.2 0.22 11.5 11.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A CNDH2_C PF16858.5 KFR01281.1 - 0.77 9.6 19.5 0.98 9.2 19.5 1.0 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Vfa1 PF08432.10 KFR01281.1 - 0.83 10.0 22.9 1.1 9.6 22.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Peptidase_C58 PF03543.14 KFR01281.1 - 0.92 9.2 9.9 1.2 8.9 9.9 1.2 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen GAGA_bind PF06217.12 KFR01281.1 - 1.2 9.3 13.8 1.4 9.1 13.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DASH_Spc19 PF08287.11 KFR01281.1 - 1.7 8.5 20.7 2.3 8.1 20.7 1.1 1 0 0 1 1 1 0 Spc19 RR_TM4-6 PF06459.12 KFR01281.1 - 2.6 7.8 16.7 3.5 7.4 16.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CobT PF06213.12 KFR01281.1 - 3.7 6.9 23.3 4.8 6.5 23.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4746 PF15928.5 KFR01281.1 - 4.4 6.6 18.8 5.3 6.4 18.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RNA_pol_3_Rpc31 PF11705.8 KFR01281.1 - 4.5 7.5 23.8 5.8 7.1 23.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DDHD PF02862.17 KFR01281.1 - 5.9 7.0 8.9 7.6 6.6 8.9 1.2 1 0 0 1 1 1 0 DDHD domain RP-C_C PF11800.8 KFR01281.1 - 6.3 6.8 12.4 9.5 6.2 12.4 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region SAPS PF04499.15 KFR01281.1 - 6.9 5.3 15.5 8.3 5.1 15.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.16 KFR01281.1 - 8.4 6.4 8.1 10 6.1 8.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Phe_ZIP PF08916.11 KFR01282.1 - 3.2e-20 72.6 6.1 6.7e-20 71.6 6.1 1.6 1 0 0 1 1 1 1 Phenylalanine zipper SH2 PF00017.24 KFR01282.1 - 8.8e-13 48.2 0.3 3.8e-12 46.1 0.1 2.0 2 0 0 2 2 2 1 SH2 domain PH PF00169.29 KFR01282.1 - 3.7e-12 46.7 0.0 8e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KFR01282.1 - 0.049 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain EF-hand_1 PF00036.32 KFR01283.1 - 5.2e-15 53.8 3.8 5.1e-06 25.7 0.9 3.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFR01283.1 - 1.4e-10 40.3 3.8 2e-06 27.2 0.8 3.2 2 1 1 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KFR01283.1 - 1.4e-10 41.4 0.2 9.2e-05 22.8 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFR01283.1 - 5.1e-08 32.7 1.2 0.015 15.1 0.1 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KFR01283.1 - 0.0004 19.8 2.2 0.0017 17.7 1.0 2.7 2 0 0 2 2 2 1 EF hand 3Beta_HSD PF01073.19 KFR01284.1 - 1.4e-50 171.9 0.1 1.7e-50 171.6 0.1 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFR01284.1 - 7.6e-11 41.9 0.0 9.4e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KFR01284.1 - 2.1e-06 27.1 0.0 2.6e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 KFR01284.1 - 0.024 13.7 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Collagen PF01391.18 KFR01285.1 - 8.9e-20 70.2 75.1 2.3e-09 36.9 35.9 3.2 2 1 0 2 2 2 2 Collagen triple helix repeat (20 copies) EMI PF07546.13 KFR01285.1 - 4.5e-18 65.8 11.0 7e-18 65.2 11.0 1.3 1 0 0 1 1 1 1 EMI domain Roc PF08477.13 KFR01286.1 - 2.2e-09 37.6 0.0 3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFR01286.1 - 4.9e-07 29.5 0.0 6.1e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KFR01286.1 - 0.0094 15.4 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Rabaptin PF03528.15 KFR01287.1 - 1.1e-280 931.3 54.0 1.1e-280 931.3 54.0 2.8 2 1 0 2 2 2 1 Rabaptin Rab5-bind PF09311.11 KFR01287.1 - 6.4e-136 452.7 63.6 6.4e-136 452.7 63.6 3.9 2 1 1 3 3 3 1 Rabaptin-like protein Fez1 PF06818.15 KFR01287.1 - 0.0047 17.4 24.6 0.0047 17.4 24.6 5.5 2 2 2 5 5 5 2 Fez1 TruB_C_2 PF16198.5 KFR01287.1 - 0.72 10.1 8.2 0.96 9.6 0.3 4.6 3 0 0 3 3 3 0 tRNA pseudouridylate synthase B C-terminal domain Nup88 PF10168.9 KFR01288.1 - 1.2e-289 962.2 0.5 1.3e-289 962.0 0.5 1.0 1 0 0 1 1 1 1 Nuclear pore component Syntaxin-6_N PF09177.11 KFR01288.1 - 0.033 14.7 5.8 0.1 13.2 5.7 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Flagellin_N PF00669.20 KFR01288.1 - 0.086 12.9 0.7 0.19 11.8 0.7 1.6 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region NOG1_N PF17835.1 KFR01288.1 - 0.39 10.7 7.8 0.059 13.3 1.9 2.2 1 1 1 2 2 2 0 NOG1 N-terminal helical domain YtxH PF12732.7 KFR01288.1 - 0.58 10.7 3.2 7.1 7.3 3.2 2.4 1 1 0 1 1 1 0 YtxH-like protein FapA PF03961.13 KFR01288.1 - 0.89 8.1 11.4 1.2 7.6 11.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A BLOC1_2 PF10046.9 KFR01288.1 - 2.7 8.3 10.7 38 4.7 6.8 3.1 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Dna2 PF08696.11 KFR01288.1 - 3.4 7.4 10.4 0.77 9.5 5.4 2.1 1 1 1 2 2 2 0 DNA replication factor Dna2 Exonuc_VII_L PF02601.15 KFR01288.1 - 3.7 7.0 10.1 5.8 6.4 10.1 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_23 PF13476.6 KFR01288.1 - 5.1 7.5 18.1 9.8 6.6 18.1 1.5 1 1 0 1 1 1 0 AAA domain TolA_bind_tri PF16331.5 KFR01288.1 - 5.9 7.1 12.7 2.5 8.2 3.6 2.7 2 0 0 2 2 2 0 TolA binding protein trimerisation RPA_interact_C PF14768.6 KFR01289.1 - 3.6e-19 69.1 3.9 5.6e-19 68.5 3.9 1.3 1 0 0 1 1 1 1 Replication protein A interacting C-terminal RPA_interact_M PF14767.6 KFR01289.1 - 4.2e-08 33.7 8.2 4.2e-08 33.7 8.2 1.6 2 0 0 2 2 2 1 Replication protein A interacting middle DUF5318 PF17249.2 KFR01289.1 - 0.0024 17.6 0.4 0.0036 17.1 0.1 1.4 2 0 0 2 2 2 1 Family of unknown function (DUF5318) zf-RRPl_C4 PF17026.5 KFR01289.1 - 0.033 14.3 1.9 0.062 13.4 1.1 1.8 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type MAM33 PF02330.16 KFR01290.1 - 4.5e-42 144.4 3.3 5.1e-42 144.2 3.3 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein HA2 PF04408.23 KFR01291.1 - 9e-20 71.0 0.0 1.9e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFR01291.1 - 2.3e-16 59.9 0.0 5e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFR01291.1 - 1.8e-13 50.8 0.0 4.1e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFR01291.1 - 3.6e-05 23.6 0.2 7.6e-05 22.5 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFR01291.1 - 0.0084 16.4 0.0 0.029 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain DER1 PF04511.15 KFR01292.1 - 1.9e-65 220.4 12.7 2.1e-65 220.2 12.7 1.0 1 0 0 1 1 1 1 Der1-like family Oleosin PF01277.17 KFR01292.1 - 1 9.1 3.9 1.5 8.6 0.0 2.2 1 1 1 2 2 2 0 Oleosin Mis12 PF05859.12 KFR01293.1 - 8.6e-27 93.8 2.8 1.6e-26 93.0 2.8 1.5 1 0 0 1 1 1 1 Mis12 protein DUF2018 PF09442.10 KFR01293.1 - 0.061 14.3 0.1 0.17 12.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2018) FadA PF09403.10 KFR01293.1 - 0.12 12.8 9.4 0.064 13.7 6.4 2.0 2 1 0 2 2 2 0 Adhesion protein FadA Lzipper-MIP1 PF14389.6 KFR01293.1 - 0.51 10.7 6.6 2.6 8.4 6.1 2.2 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 GreA_GreB_N PF03449.15 KFR01293.1 - 0.56 10.4 0.1 0.56 10.4 0.1 2.6 2 1 1 3 3 3 0 Transcription elongation factor, N-terminal ZapB PF06005.12 KFR01293.1 - 0.85 10.1 11.4 0.094 13.2 4.7 2.5 3 0 0 3 3 3 0 Cell division protein ZapB OmpH PF03938.14 KFR01293.1 - 1.2 9.5 12.3 3.5 8.0 12.3 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) CENP-H PF05837.12 KFR01293.1 - 2.3 8.7 7.0 17 5.9 6.1 2.1 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Cep57_MT_bd PF06657.13 KFR01293.1 - 2.9 8.4 11.3 0.71 10.4 1.1 2.8 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Prefoldin_2 PF01920.20 KFR01293.1 - 7.5 6.6 12.3 9.8 6.2 6.2 2.3 2 0 0 2 2 2 0 Prefoldin subunit Pkinase PF00069.25 KFR01294.1 - 9.1e-65 218.6 0.0 1.1e-57 195.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFR01294.1 - 4.5e-33 114.6 0.0 3.9e-31 108.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFR01294.1 - 2.2e-08 33.8 0.0 3.2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFR01294.1 - 4.4e-05 22.4 0.0 7.5e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase P2X_receptor PF00864.19 KFR01295.1 - 1.6e-162 540.8 0.2 1.9e-162 540.5 0.2 1.0 1 0 0 1 1 1 1 ATP P2X receptor Dickkopf_N PF04706.12 KFR01295.1 - 0.033 14.7 1.3 0.09 13.3 1.3 1.7 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region WAP PF00095.21 KFR01295.1 - 0.14 12.6 4.9 0.1 13.0 2.2 2.2 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' E1-E2_ATPase PF00122.20 KFR01296.1 - 2.7e-54 183.4 0.5 2.7e-54 183.4 0.5 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFR01296.1 - 2.4e-45 154.5 3.3 2.4e-45 154.5 3.3 1.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFR01296.1 - 1.7e-18 67.7 0.0 1e-14 55.3 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFR01296.1 - 2.5e-16 59.5 0.3 4.7e-16 58.6 0.3 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFR01296.1 - 8.7e-07 28.9 1.3 1.1e-06 28.5 0.3 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFR01296.1 - 0.0036 17.7 0.0 0.0093 16.4 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ank_2 PF12796.7 KFR01298.1 - 1.1e-81 269.5 24.3 1.9e-12 47.6 2.5 12.0 4 3 7 12 12 12 12 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFR01298.1 - 3.4e-69 220.5 29.6 5.3e-05 23.3 0.0 20.9 22 0 0 22 22 22 16 Ankyrin repeat Ank_4 PF13637.6 KFR01298.1 - 1.4e-63 210.4 22.7 2.1e-06 28.2 0.5 17.1 7 5 11 19 19 19 13 Ankyrin repeats (many copies) Ank PF00023.30 KFR01298.1 - 2.5e-63 207.9 37.6 1.2e-08 35.0 0.0 20.1 22 1 0 22 22 22 11 Ankyrin repeat Ank_5 PF13857.6 KFR01298.1 - 4.4e-59 195.8 29.0 4.6e-08 33.2 0.0 15.4 11 3 4 16 16 16 11 Ankyrin repeats (many copies) BTB PF00651.31 KFR01298.1 - 2.1e-16 60.1 0.1 7.8e-16 58.3 0.1 2.0 1 0 0 1 1 1 1 BTB/POZ domain FYVE PF01363.21 KFR01298.1 - 7.1e-16 58.1 10.5 1.5e-15 57.0 10.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger BACK PF07707.15 KFR01298.1 - 0.013 15.5 1.9 0.034 14.2 0.3 2.5 2 0 0 2 2 2 0 BTB And C-terminal Kelch Glyoxalase_4 PF13669.6 KFR01298.1 - 0.12 12.6 0.2 16 5.8 0.0 3.8 4 0 0 4 4 4 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FYVE_2 PF02318.16 KFR01298.1 - 1.5 9.1 11.2 0.37 11.0 7.4 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger UQ_con PF00179.26 KFR01299.1 - 2.4e-45 153.6 0.0 2.6e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFR01299.1 - 0.075 13.3 0.0 0.075 13.3 0.0 1.2 1 0 0 1 1 1 0 RWD domain MFS_1 PF07690.16 KFR01300.1 - 1.2e-35 123.2 32.0 1.2e-35 123.2 32.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFR01300.1 - 5.3e-14 51.9 23.0 7.2e-14 51.5 23.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 KFR01300.1 - 1.2e-13 50.2 21.3 3.9e-05 22.2 0.2 4.3 1 1 2 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 KFR01300.1 - 0.0007 18.3 7.5 0.0007 18.3 7.5 2.5 2 2 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 KFR01301.1 - 8.4e-29 100.6 30.0 8.4e-29 100.6 30.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFR01301.1 - 2.4e-12 46.5 9.3 2.4e-12 46.5 9.3 2.8 1 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KFR01301.1 - 1.6e-09 36.6 20.8 7.6e-07 27.8 1.2 4.2 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family Tetraspanin PF00335.20 KFR01301.1 - 1.5 8.5 12.1 0.24 11.1 5.9 2.6 2 1 0 2 2 2 0 Tetraspanin family RRM_1 PF00076.22 KFR01302.1 - 1.7e-13 50.2 0.0 2.6e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rep_fac_C PF08542.11 KFR01303.1 - 4e-27 94.4 0.0 1.1e-26 93.0 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KFR01303.1 - 1.8e-13 51.1 0.1 3e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KFR01303.1 - 3.3e-12 46.5 0.0 3.3e-10 40.0 0.1 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 KFR01303.1 - 2.9e-06 27.3 0.0 5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFR01303.1 - 5.5e-06 26.9 0.0 0.00069 20.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFR01303.1 - 6.2e-06 26.5 0.2 0.028 14.7 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_24 PF13479.6 KFR01303.1 - 3.6e-05 23.6 0.0 7.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KFR01303.1 - 4.7e-05 23.2 0.0 8.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 KFR01303.1 - 7.2e-05 22.7 0.0 8.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KFR01303.1 - 0.00011 21.6 0.0 0.0018 17.7 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KFR01303.1 - 0.00084 19.7 0.6 0.0037 17.6 0.6 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFR01303.1 - 0.0014 19.2 0.0 0.0038 17.8 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 KFR01303.1 - 0.0014 18.9 0.0 0.0041 17.4 0.0 1.9 2 0 0 2 2 1 1 AAA C-terminal domain MipZ PF09140.11 KFR01303.1 - 0.0016 17.8 0.1 0.0021 17.4 0.1 1.1 1 0 0 1 1 1 1 ATPase MipZ TniB PF05621.11 KFR01303.1 - 0.002 17.6 0.1 2.2 7.6 0.0 2.4 2 0 0 2 2 2 2 Bacterial TniB protein RuvB_N PF05496.12 KFR01303.1 - 0.0022 17.7 0.0 0.0062 16.3 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KFR01303.1 - 0.004 17.2 0.0 0.011 15.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KFR01303.1 - 0.0043 16.7 0.2 0.013 15.0 0.2 1.7 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 KFR01303.1 - 0.0054 16.5 0.2 0.016 14.9 0.2 1.8 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 KFR01303.1 - 0.0069 16.2 1.2 0.43 10.3 0.0 2.7 2 1 1 3 3 3 1 DEAD/DEAH box helicase ABC_tran PF00005.27 KFR01303.1 - 0.014 15.9 0.0 0.039 14.5 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Rad17 PF03215.15 KFR01303.1 - 0.019 14.9 0.0 0.058 13.3 0.0 1.8 1 1 1 2 2 2 0 Rad17 P-loop domain ResIII PF04851.15 KFR01303.1 - 0.021 14.8 0.2 14 5.6 0.0 3.1 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 KFR01303.1 - 0.032 14.5 0.1 0.055 13.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KFR01303.1 - 0.041 13.8 0.3 0.18 11.7 0.1 2.0 2 0 0 2 2 2 0 NTPase MeaB PF03308.16 KFR01303.1 - 0.048 12.6 0.0 0.083 11.9 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2075 PF09848.9 KFR01303.1 - 0.052 12.8 0.6 1.2 8.3 0.6 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.18 KFR01303.1 - 0.059 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SSE PF00437.20 KFR01303.1 - 0.064 12.3 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 KFR01303.1 - 0.071 13.6 0.0 0.13 12.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFR01303.1 - 0.076 13.4 0.0 0.26 11.7 0.0 2.0 1 1 0 1 1 1 0 RNA helicase DUF4597 PF15366.6 KFR01303.1 - 0.085 12.6 0.7 3.1 7.6 0.1 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4597) DNA_pol3_delta PF06144.13 KFR01303.1 - 0.15 11.8 0.3 0.27 11.0 0.1 1.5 2 0 0 2 2 1 0 DNA polymerase III, delta subunit CAP_GLY PF01302.25 KFR01304.1 - 1.2e-48 163.0 5.2 4.5e-25 87.4 0.4 2.3 2 0 0 2 2 2 2 CAP-Gly domain Strep_SA_rep PF06696.11 KFR01304.1 - 0.42 10.7 6.9 2 8.5 6.9 2.3 1 0 0 1 1 1 0 Streptococcal surface antigen repeat KaiA PF07688.12 KFR01304.1 - 0.52 10.5 4.9 0.33 11.1 1.9 2.3 2 0 0 2 2 2 0 KaiA C-terminal domain Synaptobrevin PF00957.21 KFR01304.1 - 9 6.2 11.5 0.34 10.7 2.6 3.2 2 1 1 3 3 3 0 Synaptobrevin GTF2I PF02946.14 KFR01305.1 - 1.1e-156 509.2 10.2 5.4e-31 106.5 0.2 5.3 5 0 0 5 5 5 5 GTF2I-like repeat SR-25 PF10500.9 KFR01305.1 - 4.4 6.9 20.0 0.085 12.5 12.7 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein GTF2I PF02946.14 KFR01306.1 - 8.4e-192 621.7 13.8 2.1e-33 114.2 0.0 6.2 6 0 0 6 6 6 6 GTF2I-like repeat REV1_C PF16727.5 KFR01306.1 - 0.0035 17.7 0.5 11 6.4 0.0 4.5 4 0 0 4 4 4 1 DNA repair protein REV1 C-terminal domain NRBF2 PF08961.10 KFR01306.1 - 0.069 12.7 1.5 2.3 7.8 0.0 2.9 3 0 0 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator SH3_1 PF00018.28 KFR01307.1 - 4.2e-31 106.3 0.6 2.3e-15 55.9 0.1 3.3 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 KFR01307.1 - 8.6e-24 83.1 0.1 2.3e-10 40.1 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 KFR01307.1 - 4.9e-22 77.4 0.0 2.5e-12 46.3 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain NECFESHC PF16621.5 KFR01307.1 - 5.2e-22 77.6 10.8 5.2e-22 77.6 10.8 2.3 2 0 0 2 2 2 1 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 p47_phox_C PF08944.11 KFR01307.1 - 6.1e-16 57.5 4.9 1.3e-15 56.5 4.9 1.6 1 0 0 1 1 1 1 NADPH oxidase subunit p47Phox, C terminal domain PX PF00787.24 KFR01307.1 - 3.2e-15 56.1 0.9 3.2e-15 56.1 0.9 2.3 2 0 0 2 2 2 1 PX domain hSH3 PF14603.6 KFR01307.1 - 0.00015 22.1 0.0 0.11 13.0 0.0 2.5 2 0 0 2 2 2 2 Helically-extended SH3 domain SH3_3 PF08239.11 KFR01307.1 - 0.00039 20.6 1.1 0.072 13.4 0.0 2.4 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_6 PF12913.7 KFR01307.1 - 0.096 12.3 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 SH3 domain (SH3b1 type) RCC1 PF00415.18 KFR01308.1 - 2.2e-56 188.3 13.1 1.3e-09 38.5 0.1 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFR01308.1 - 1.4e-28 98.0 33.4 8.4e-08 31.8 0.3 7.8 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RVT_1 PF00078.27 KFR01314.1 - 0.0069 15.9 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFR01315.1 - 0.011 15.3 0.0 0.02 14.4 0.0 1.4 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Cadherin PF00028.17 KFR01320.1 - 2.8e-92 303.4 0.0 1.4e-17 63.9 0.0 6.5 6 0 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.12 KFR01320.1 - 8.4e-17 60.8 0.1 1.1e-09 37.9 0.0 5.0 5 0 0 5 5 5 2 Cadherin-like Cadherin_4 PF17803.1 KFR01320.1 - 1.6e-05 25.4 6.2 0.17 12.5 0.0 4.8 4 0 0 4 4 4 2 Bacterial cadherin-like domain Cadherin_C_2 PF16492.5 KFR01320.1 - 2.1e-05 25.2 0.0 7.8e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal LCCL PF03815.19 KFR01326.1 - 5e-51 170.8 15.7 1.4e-26 92.5 0.3 3.2 3 0 0 3 3 3 2 LCCL domain CAP PF00188.26 KFR01326.1 - 1.6e-20 74.2 1.5 1.6e-20 74.2 1.5 2.1 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Rxt3 PF08642.10 KFR01326.1 - 0.0025 18.6 1.7 0.086 13.6 0.0 3.0 3 0 0 3 3 3 1 Histone deacetylation protein Rxt3 DUF2889 PF11136.8 KFR01326.1 - 0.065 13.6 0.2 0.17 12.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2889) CAP PF00188.26 KFR01327.1 - 2.6e-25 89.7 2.2 3.8e-25 89.2 2.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family GST_N_3 PF13417.6 KFR01328.1 - 3.9e-11 43.2 0.0 8.5e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFR01328.1 - 2.2e-10 40.7 0.1 5.9e-10 39.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFR01328.1 - 2.4e-09 37.1 0.0 4.8e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFR01328.1 - 1.8e-08 34.5 0.1 5e-08 33.1 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFR01328.1 - 3.2e-08 33.7 0.0 8.1e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFR01328.1 - 5.2e-07 29.8 0.0 2.7e-06 27.5 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KFR01328.1 - 0.0022 18.3 0.0 0.0061 16.9 0.0 1.7 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KFR01328.1 - 0.024 15.4 0.0 0.049 14.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain DUF3206 PF11472.8 KFR01328.1 - 0.03 14.3 0.1 0.052 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) DUF1617 PF07761.12 KFR01328.1 - 0.032 14.3 0.9 0.057 13.5 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1617) Fmp27_WPPW PF10359.9 KFR01328.1 - 0.049 12.5 0.1 0.067 12.0 0.1 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain MCR_C PF04609.12 KFR01328.1 - 0.12 11.4 0.2 0.2 10.7 0.2 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C CCDC-167 PF15188.6 KFR01328.1 - 5.7 7.3 7.7 13 6.2 0.2 2.5 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 E1_DerP2_DerF2 PF02221.15 KFR01330.1 - 1.6e-07 31.8 0.0 2e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 ML domain TMEM70 PF06979.12 KFR01331.1 - 5.2e-57 191.9 7.6 6.2e-57 191.7 7.6 1.1 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex Skp1_POZ PF03931.15 KFR01332.1 - 3.1e-11 43.3 0.0 4.3e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain PTAC PF06130.12 KFR01332.1 - 0.13 12.5 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosphate propanoyltransferase UQ_con PF00179.26 KFR01333.1 - 3.3e-34 117.5 0.2 3.6e-34 117.4 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KFR01333.1 - 0.016 15.1 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 UEV domain Prok-E2_A PF14457.6 KFR01333.1 - 0.11 12.2 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family A dsrm PF00035.26 KFR01334.1 - 2.7e-50 168.9 2.6 2.6e-13 50.5 0.1 4.8 4 0 0 4 4 4 4 Double-stranded RNA binding motif Staufen_C PF16482.5 KFR01334.1 - 1.1e-20 73.8 0.4 2.9e-16 59.6 0.3 5.2 5 1 0 5 5 5 1 Staufen C-terminal domain DND1_DSRM PF14709.7 KFR01334.1 - 2.2e-07 31.0 5.2 0.16 12.3 0.1 5.3 4 2 0 4 4 4 2 double strand RNA binding domain from DEAD END PROTEIN 1 Dicer_dimer PF03368.14 KFR01334.1 - 0.014 15.6 1.7 55 4.0 0.0 4.4 4 0 0 4 4 4 0 Dicer dimerisation domain Ribosomal_L30_N PF08079.12 KFR01335.1 - 1e-27 96.1 15.9 1.9e-27 95.3 15.9 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KFR01335.1 - 1.4e-25 88.9 1.2 4.1e-25 87.4 1.2 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e TSP_1 PF00090.19 KFR01336.1 - 0.00013 22.1 2.1 0.00013 22.1 2.1 3.2 4 0 0 4 4 4 1 Thrombospondin type 1 domain Somatomedin_B PF01033.17 KFR01336.1 - 0.00059 20.2 16.2 0.00059 20.2 16.2 3.4 3 0 0 3 3 3 1 Somatomedin B domain TRF PF08558.10 KFR01337.1 - 6.3e-25 88.2 3.0 9.6e-25 87.6 3.0 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 KFR01337.1 - 2.8e-09 37.0 0.4 2.8e-09 37.0 0.4 2.3 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFR01337.1 - 0.00036 20.7 0.0 0.00091 19.4 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain TPR_7 PF13176.6 KFR01337.1 - 0.14 12.2 0.0 0.44 10.7 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Ank_2 PF12796.7 KFR01338.1 - 3.5e-95 312.7 33.2 9.9e-13 48.5 0.0 8.0 3 2 7 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFR01338.1 - 3.1e-59 196.6 15.1 1.8e-08 34.8 0.0 10.6 4 3 8 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.30 KFR01338.1 - 1.7e-57 189.4 18.5 1.1e-06 28.8 0.0 14.6 13 1 1 14 14 14 13 Ankyrin repeat Ank_3 PF13606.6 KFR01338.1 - 2.9e-57 183.9 15.9 0.00017 21.7 0.0 15.9 15 0 0 15 15 15 13 Ankyrin repeat Ank_5 PF13857.6 KFR01338.1 - 4.8e-50 167.0 12.6 8.7e-07 29.1 0.0 12.1 3 3 8 12 12 12 10 Ankyrin repeats (many copies) Ion_trans PF00520.31 KFR01338.1 - 6.1e-16 58.4 18.7 9.3e-16 57.8 18.7 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KFR01338.1 - 4.1e-05 22.4 19.4 0.0037 16.0 12.7 2.2 1 1 1 2 2 2 2 Polycystin cation channel SchA_CurD PF04486.12 KFR01338.1 - 0.13 12.3 0.0 0.38 10.8 0.0 1.8 1 0 0 1 1 1 0 SchA/CurD like domain Cadherin PF00028.17 KFR01341.1 - 6.5e-84 276.5 6.3 1.6e-18 66.9 0.2 5.2 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFR01341.1 - 5e-55 185.8 1.4 1.1e-54 184.7 0.6 2.0 2 0 0 2 2 2 1 Cadherin cytoplasmic region Cadherin_3 PF16184.5 KFR01341.1 - 1.3e-11 44.5 2.3 0.0051 16.8 0.0 5.1 5 0 0 5 5 5 3 Cadherin-like Cadherin_2 PF08266.12 KFR01341.1 - 0.00011 22.0 0.0 2.3 8.1 0.0 4.4 4 0 0 4 4 4 1 Cadherin-like Cadherin_4 PF17803.1 KFR01341.1 - 0.039 14.6 0.8 0.039 14.6 0.8 4.3 4 0 0 4 4 4 0 Bacterial cadherin-like domain ASFV_J13L PF05568.11 KFR01341.1 - 0.076 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Invasin_D3 PF09134.10 KFR01341.1 - 1.2 9.5 10.9 14 6.0 0.0 4.7 4 2 2 6 6 6 0 Invasin, domain 3 He_PIG PF05345.12 KFR01341.1 - 2.7 8.2 4.8 66 3.8 0.1 4.5 4 0 0 4 4 4 0 Putative Ig domain DUF5527 PF17665.1 KFR01341.1 - 3.4 7.2 4.1 0.86 9.1 0.5 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5527) Cohesin_HEAT PF12765.7 KFR01342.1 - 0.0009 19.5 0.5 0.0025 18.1 0.2 1.9 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.6 KFR01342.1 - 0.061 13.7 0.5 1.7 9.1 0.2 2.9 2 1 0 2 2 2 0 HEAT repeats DUF3323 PF11796.8 KFR01342.1 - 0.063 13.2 1.2 1.4 8.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) DUF3437 PF11919.8 KFR01342.1 - 0.063 13.2 0.0 0.35 10.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) DUF3384 PF11864.8 KFR01342.1 - 0.11 11.4 0.2 0.25 10.2 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3384) HEAT PF02985.22 KFR01342.1 - 0.12 12.6 0.1 0.12 12.6 0.1 3.7 5 0 0 5 5 5 0 HEAT repeat PqqD PF05402.12 KFR01342.1 - 0.13 12.6 0.0 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) FdhE PF04216.12 KFR01342.1 - 0.22 11.4 3.2 0.35 10.7 2.0 1.7 1 1 1 2 2 2 0 Protein involved in formate dehydrogenase formation TPR_2 PF07719.17 KFR01350.1 - 2.7e-09 36.4 0.0 0.00085 19.3 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFR01350.1 - 3.3e-07 30.8 0.2 0.035 14.8 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFR01350.1 - 4.6e-05 23.5 1.5 0.0099 16.0 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFR01350.1 - 7.9e-05 23.2 2.6 0.83 10.6 0.2 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFR01350.1 - 0.00017 22.0 0.8 0.017 15.6 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFR01350.1 - 0.00019 21.0 0.0 0.005 16.5 0.0 2.5 2 1 0 2 2 2 1 TPR repeat TPR_1 PF00515.28 KFR01350.1 - 0.0002 21.0 0.0 0.89 9.5 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFR01350.1 - 0.00081 19.6 0.0 0.11 12.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat ChAPs PF09295.10 KFR01350.1 - 0.0018 17.4 0.3 0.0029 16.7 0.2 1.3 1 1 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) Vasohibin PF14822.6 KFR01350.1 - 0.078 12.2 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Vasohibin Maf_N PF08383.11 KFR01350.1 - 2.5 8.0 4.9 0.54 10.1 0.3 2.3 3 0 0 3 3 3 0 Maf N-terminal region Pkinase PF00069.25 KFR01351.1 - 1.9e-69 234.0 0.0 2.5e-69 233.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR01351.1 - 9.8e-38 129.9 0.0 1.5e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KFR01351.1 - 4.4e-13 49.7 0.0 1.7e-12 47.8 0.0 2.0 2 0 0 2 2 2 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 KFR01351.1 - 1.7e-05 24.3 0.0 2.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFR01351.1 - 0.0026 17.4 0.1 0.0046 16.6 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KFR01351.1 - 0.0039 16.6 0.1 0.0082 15.5 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFR01351.1 - 0.055 13.4 0.2 0.15 11.9 0.2 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFR01351.1 - 0.091 11.7 0.1 0.14 11.1 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Ribosomal_L37e PF01907.19 KFR01352.1 - 4.2e-27 94.1 15.1 7.7e-27 93.2 15.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 KFR01352.1 - 0.0064 16.5 1.7 0.01 15.8 1.7 1.3 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 KFR01352.1 - 0.23 11.5 1.4 0.32 11.0 1.4 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FeS PF04060.13 KFR01352.1 - 0.53 10.0 4.0 0.57 9.9 0.7 2.1 2 0 0 2 2 2 0 Putative Fe-S cluster MACPF PF01823.19 KFR01353.1 - 1.5e-37 129.7 1.4 3e-37 128.8 0.2 1.8 1 1 1 2 2 2 1 MAC/Perforin domain Kazal_3 PF18434.1 KFR01353.1 - 7.3e-21 73.7 9.3 7.3e-21 73.7 9.3 4.1 3 0 0 3 3 3 2 Kazal-type serine protease inhibitor domain Sushi PF00084.20 KFR01353.1 - 8e-17 61.6 10.2 1.5e-11 44.7 0.6 3.8 4 0 0 4 4 4 2 Sushi repeat (SCR repeat) TSP_1 PF00090.19 KFR01353.1 - 4.6e-09 36.3 23.2 3.7e-06 27.0 3.5 5.5 5 1 1 6 6 6 2 Thrombospondin type 1 domain Ldl_recept_a PF00057.18 KFR01353.1 - 1.9e-06 27.9 14.5 1.9e-06 27.9 14.5 4.3 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A MACPF PF01823.19 KFR01354.1 - 4.4e-43 147.8 2.2 4.8e-43 147.7 1.0 1.7 2 0 0 2 2 2 1 MAC/Perforin domain Sushi PF00084.20 KFR01354.1 - 3.2e-17 62.8 6.2 7e-10 39.4 1.1 4.4 5 0 0 5 5 5 2 Sushi repeat (SCR repeat) TSP_1 PF00090.19 KFR01354.1 - 1.6e-12 47.4 54.9 1e-06 28.8 0.6 6.0 5 0 0 5 5 5 3 Thrombospondin type 1 domain Ldl_recept_a PF00057.18 KFR01354.1 - 4.9e-11 42.6 14.1 4.9e-11 42.6 14.1 4.5 5 0 0 5 5 5 1 Low-density lipoprotein receptor domain class A PI-PLC-X PF00388.19 KFR01355.1 - 0.0006 19.4 0.0 0.00093 18.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain OrgA_MxiK PF09482.10 KFR01356.1 - 0.1 12.5 0.0 0.1 12.5 0.0 1.0 1 0 0 1 1 1 0 Bacterial type III secretion apparatus protein (OrgA_MxiK) CoA_trans PF01144.23 KFR01357.1 - 2.8e-124 412.6 2.2 1.3e-75 253.5 0.4 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KFR01357.1 - 0.0015 18.5 0.1 0.003 17.5 0.1 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DUF5561 PF17716.1 KFR01358.1 - 7.9e-115 382.5 1.9 9.2e-115 382.2 1.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5561) F-box-like PF12937.7 KFR01359.1 - 4.2e-08 32.9 1.4 1.2e-07 31.5 1.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFR01359.1 - 7.5e-07 28.9 0.1 1.8e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 F-box domain Arf PF00025.21 KFR01359.1 - 0.032 13.7 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family PRANC PF09372.10 KFR01359.1 - 0.079 13.3 0.0 0.42 11.0 0.0 2.1 2 0 0 2 2 2 0 PRANC domain Gtr1_RagA PF04670.12 KFR01359.1 - 0.099 12.0 0.2 0.18 11.1 0.2 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region zf-HC5HC2H_2 PF13832.6 KFR01370.1 - 2.5e-30 104.9 11.4 4.5e-30 104.0 11.4 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFR01370.1 - 1.3e-20 73.4 10.6 3.2e-20 72.2 10.6 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain DUF2180 PF09947.9 KFR01370.1 - 2 8.4 8.1 3.3 7.7 4.8 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) DnaJ PF00226.31 KFR01372.1 - 9.6e-18 64.1 1.5 2.5e-17 62.7 1.5 1.8 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-binding PF00249.31 KFR01372.1 - 5.9e-12 45.6 0.6 4.3e-07 30.0 0.2 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFR01372.1 - 6.1e-06 26.4 0.2 0.012 15.8 0.3 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF4234 PF14018.6 KFR01372.1 - 0.051 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) HemY_N PF07219.13 KFR01372.1 - 0.061 13.5 0.2 0.22 11.8 0.0 2.0 2 0 0 2 2 2 0 HemY protein N-terminus Tmemb_55A PF09788.9 KFR01373.1 - 0.017 14.2 0.2 0.02 14.0 0.2 1.0 1 0 0 1 1 1 0 Transmembrane protein 55A RAWUL PF16207.5 KFR01374.1 - 1.1e-21 77.3 0.6 2.7e-21 76.0 0.6 1.7 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 KFR01374.1 - 0.011 15.6 2.5 0.02 14.7 2.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFR01374.1 - 0.047 13.6 2.7 0.079 12.8 2.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFR01374.1 - 0.088 13.2 2.2 0.18 12.2 2.2 1.6 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 KFR01374.1 - 0.25 11.7 1.7 0.53 10.6 1.7 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFR01374.1 - 0.71 9.8 4.9 1.5 8.7 4.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Arm PF00514.23 KFR01375.1 - 3.3e-38 128.5 19.3 9.1e-08 31.9 0.0 9.0 9 0 0 9 9 9 7 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KFR01375.1 - 3.9e-14 51.6 12.9 0.11 12.8 0.0 8.5 9 0 0 9 9 8 3 HEAT repeat HEAT_2 PF13646.6 KFR01375.1 - 2.1e-12 47.3 8.6 0.012 16.0 0.4 5.3 2 2 4 6 6 6 4 HEAT repeats Cnd1 PF12717.7 KFR01375.1 - 1.1e-11 45.0 1.3 0.15 12.1 0.2 5.3 1 1 4 5 5 5 4 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KFR01375.1 - 8.2e-11 42.2 15.2 0.00092 19.7 0.0 6.9 5 2 2 7 7 7 4 HEAT-like repeat DNA_alkylation PF08713.11 KFR01375.1 - 1.1e-08 35.0 0.0 1.3 8.7 0.0 4.4 2 1 0 4 4 4 3 DNA alkylation repair enzyme Adaptin_N PF01602.20 KFR01375.1 - 4.6e-07 28.8 3.4 0.034 12.7 0.6 3.7 1 1 2 3 3 3 2 Adaptin N terminal region CHASE6_C PF17150.4 KFR01375.1 - 1.3e-06 29.0 1.2 5.8 7.6 0.0 5.9 5 1 0 6 6 6 1 C-terminal domain of two-partite extracellular sensor domain CLASP_N PF12348.8 KFR01375.1 - 4.5e-06 26.4 0.1 0.027 14.1 0.0 3.7 2 1 0 3 3 3 1 CLASP N terminal Atx10homo_assoc PF09759.9 KFR01375.1 - 2.2e-05 24.4 0.3 2.3 8.3 0.0 4.9 3 2 2 5 5 5 1 Spinocerebellar ataxia type 10 protein domain RTP1_C1 PF10363.9 KFR01375.1 - 0.00047 20.3 0.3 0.035 14.3 0.3 3.2 3 2 0 3 3 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Proteasom_PSMB PF10508.9 KFR01375.1 - 0.0023 16.5 2.0 0.0074 14.9 1.1 2.3 1 1 0 2 2 2 1 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.8 KFR01375.1 - 0.02 15.0 0.2 1.1 9.4 0.1 3.3 3 1 0 4 4 4 0 V-ATPase subunit H Tti2 PF10521.9 KFR01375.1 - 0.034 13.7 0.0 0.92 9.0 0.0 2.3 2 0 0 2 2 2 0 Tti2 family Vps54 PF07928.12 KFR01375.1 - 0.041 14.3 0.1 0.2 12.1 0.1 2.4 1 1 0 1 1 1 0 Vps54-like protein Rcd1 PF04078.13 KFR01375.1 - 0.045 13.0 0.9 0.56 9.5 0.1 3.0 2 1 2 4 4 4 0 Cell differentiation family, Rcd1-like XPC-binding PF09280.11 KFR01375.1 - 0.053 13.3 0.1 49 3.8 0.0 4.2 4 0 0 4 4 4 0 XPC-binding domain DUF3731 PF12531.8 KFR01375.1 - 0.13 12.1 1.1 2.2 8.0 0.3 2.7 2 1 0 2 2 2 0 DNA-K related protein HEAT_PBS PF03130.16 KFR01375.1 - 0.16 12.7 10.2 0.88 10.4 0.4 5.6 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat API5 PF05918.11 KFR01375.1 - 0.29 9.9 1.6 3.8 6.2 0.3 2.9 2 1 1 4 4 4 0 Apoptosis inhibitory protein 5 (API5) MMS19_C PF12460.8 KFR01375.1 - 0.3 10.2 4.1 1.2 8.2 0.4 2.9 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal DUF3361 PF11841.8 KFR01375.1 - 0.58 10.1 4.5 1.2 9.1 0.4 2.7 3 1 0 3 3 2 0 Domain of unknown function (DUF3361) PIP5K PF01504.18 KFR01376.1 - 3e-77 259.5 0.2 4e-77 259.1 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Arm PF00514.23 KFR01377.1 - 6.6e-48 159.4 17.8 3.3e-07 30.1 0.0 11.1 11 0 0 11 11 11 8 Armadillo/beta-catenin-like repeat EDR1 PF14381.6 KFR01377.1 - 2.4e-39 135.2 0.0 5.6e-39 133.9 0.0 1.6 1 0 0 1 1 1 1 Ethylene-responsive protein kinase Le-CTR1 HEAT_2 PF13646.6 KFR01377.1 - 1.1e-28 99.4 15.7 9.9e-06 25.9 0.0 6.5 3 1 3 6 6 6 6 HEAT repeats HEAT PF02985.22 KFR01377.1 - 8e-21 72.4 12.3 0.12 12.7 0.1 9.5 10 0 0 10 10 9 5 HEAT repeat HEAT_EZ PF13513.6 KFR01377.1 - 4.4e-19 68.6 5.9 0.0034 17.8 0.0 8.8 8 1 1 9 9 9 4 HEAT-like repeat Adaptin_N PF01602.20 KFR01377.1 - 2e-10 39.9 7.9 3.8e-07 29.1 6.3 3.8 1 1 2 3 3 3 3 Adaptin N terminal region V-ATPase_H_C PF11698.8 KFR01377.1 - 2e-09 37.6 3.2 0.25 11.5 0.4 6.0 2 2 5 7 7 7 4 V-ATPase subunit H Cnd1 PF12717.7 KFR01377.1 - 9.4e-08 32.3 14.2 0.09 12.8 0.1 5.4 4 2 3 7 7 6 3 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.14 KFR01377.1 - 1.3e-06 28.0 0.6 0.022 14.0 0.6 3.4 1 1 0 1 1 1 1 V-ATPase subunit H Proteasom_PSMB PF10508.9 KFR01377.1 - 3.5e-05 22.5 3.8 0.057 11.9 3.3 2.6 2 1 0 2 2 2 2 Proteasome non-ATPase 26S subunit Arm_2 PF04826.13 KFR01377.1 - 7.8e-05 22.3 10.0 0.68 9.3 1.7 5.3 1 1 1 3 3 3 2 Armadillo-like CLASP_N PF12348.8 KFR01377.1 - 0.00016 21.4 0.4 2.6 7.5 0.0 3.6 2 1 1 3 3 3 3 CLASP N terminal UNC45-central PF11701.8 KFR01377.1 - 0.1 12.6 5.9 2 8.4 0.2 3.2 1 1 2 3 3 3 0 Myosin-binding striated muscle assembly central UME PF08064.13 KFR01377.1 - 0.11 12.4 0.1 1.3 8.9 0.0 3.0 3 0 0 3 3 3 0 UME (NUC010) domain Atx10homo_assoc PF09759.9 KFR01377.1 - 0.11 12.5 2.3 6.5 6.8 0.0 4.0 3 1 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain MMS19_N PF14500.6 KFR01377.1 - 0.12 11.9 1.1 2.5 7.6 0.1 3.6 3 1 2 6 6 6 0 Dos2-interacting transcription regulator of RNA-Pol-II RTP1_C1 PF10363.9 KFR01377.1 - 0.2 11.9 4.2 37 4.5 0.1 4.1 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3361 PF11841.8 KFR01377.1 - 0.48 10.4 5.9 2.6 8.0 0.4 4.0 2 2 0 3 3 3 0 Domain of unknown function (DUF3361) SelR PF01641.18 KFR01378.1 - 1.7e-30 105.6 0.2 1.9e-30 105.4 0.2 1.0 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 KFR01378.1 - 0.013 15.2 0.1 0.016 14.9 0.1 1.3 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Yippee-Mis18 PF03226.14 KFR01378.1 - 0.018 15.3 0.1 0.019 15.2 0.1 1.2 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HECT_2 PF09814.9 KFR01378.1 - 0.045 12.6 0.0 0.045 12.6 0.0 1.0 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding OTU PF02338.19 KFR01379.1 - 6.7e-25 88.0 0.0 1.2e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KFR01379.1 - 0.0082 15.6 0.0 0.79 9.1 0.1 2.2 2 0 0 2 2 2 2 Peptidase C65 Otubain AIP3 PF03915.13 KFR01380.1 - 1.1e-12 47.7 10.4 2.2e-09 36.9 0.0 6.1 4 2 0 5 5 5 4 Actin interacting protein 3 RhoGAP PF00620.27 KFR01381.1 - 1.6e-50 170.9 0.1 3.1e-50 170.0 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain PDZ_6 PF17820.1 KFR01381.1 - 2.8e-15 55.9 0.2 1.5e-14 53.6 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PH_9 PF15410.6 KFR01381.1 - 4.4e-14 52.9 0.0 1.4e-13 51.2 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFR01381.1 - 5.7e-14 52.5 1.7 3.8e-13 49.9 0.2 2.9 2 0 0 2 2 2 1 PH domain PDZ PF00595.24 KFR01381.1 - 8.6e-10 38.8 0.0 2.8e-09 37.2 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFR01381.1 - 5e-06 26.8 0.1 2e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PH_11 PF15413.6 KFR01381.1 - 0.0035 17.8 1.6 0.01 16.3 0.0 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain Pribosyltran PF00156.27 KFR01383.1 - 9.2e-15 54.5 0.0 1.4e-06 27.9 0.0 2.0 2 0 0 2 2 2 2 Phosphoribosyl transferase domain Enkurin PF13864.6 KFR01384.1 - 1e-25 90.0 8.9 1e-25 90.0 8.9 2.3 3 0 0 3 3 3 1 Calmodulin-binding 7TMR-HDED PF07697.11 KFR01384.1 - 0.0029 17.8 0.2 0.0032 17.6 0.2 1.1 1 0 0 1 1 1 1 7TM-HD extracellular SKI PF01202.22 KFR01385.1 - 1.2e-34 119.7 0.0 2.1e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase Thr_synth_N PF14821.6 KFR01385.1 - 2.9e-13 49.8 0.0 8.9e-13 48.3 0.0 1.9 1 0 0 1 1 1 1 Threonine synthase N terminus AAA_18 PF13238.6 KFR01385.1 - 3.7e-07 30.8 0.0 8.5e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain PALP PF00291.25 KFR01385.1 - 1.8e-06 27.6 0.0 3.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AAA PF00004.29 KFR01385.1 - 2.6e-05 24.6 0.0 0.0004 20.8 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KFR01385.1 - 0.00026 20.5 0.0 0.00044 19.7 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 KFR01385.1 - 0.0031 17.9 0.2 0.035 14.5 0.0 2.8 4 1 0 4 4 3 1 AAA domain RuvB_N PF05496.12 KFR01385.1 - 0.0049 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KFR01385.1 - 0.0051 17.0 0.0 0.017 15.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFR01385.1 - 0.0059 16.9 0.1 0.044 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Acid_PPase PF12689.7 KFR01385.1 - 0.033 14.0 0.0 0.084 12.7 0.0 1.6 1 0 0 1 1 1 0 Acid Phosphatase IstB_IS21 PF01695.17 KFR01385.1 - 0.046 13.4 0.2 0.27 11.0 0.0 2.3 3 0 0 3 3 3 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 KFR01385.1 - 0.046 13.0 0.0 0.09 12.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Cytidylate_kin PF02224.18 KFR01385.1 - 0.068 12.9 0.0 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Cytidylate kinase AAA_24 PF13479.6 KFR01385.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFR01385.1 - 0.16 12.3 0.0 1.2 9.5 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain 7tm_3 PF00003.22 KFR01386.1 - 2.2e-34 119.3 22.6 3.1e-34 118.7 22.6 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Myosin_head PF00063.21 KFR01389.1 - 2.8e-204 680.2 7.4 4.2e-204 679.6 7.4 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Pkinase PF00069.25 KFR01389.1 - 4.4e-61 206.6 0.0 9.1e-61 205.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR01389.1 - 6.6e-44 150.1 0.0 1.3e-43 149.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase IQ PF00612.27 KFR01389.1 - 2.5e-24 82.7 19.0 1e-05 24.9 0.2 5.8 5 0 0 5 5 5 5 IQ calmodulin-binding motif Kinase-like PF14531.6 KFR01389.1 - 0.00032 20.1 0.3 0.0018 17.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFR01389.1 - 0.0011 19.0 0.0 1.1 9.1 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family AAA_22 PF13401.6 KFR01389.1 - 0.0025 18.1 0.0 0.012 15.9 0.0 2.2 1 0 0 1 1 1 1 AAA domain Pyridoxal_deC PF00282.19 KFR01390.1 - 2.8e-136 454.1 0.0 3.4e-136 453.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KFR01390.1 - 4.9e-05 22.4 0.0 0.0003 19.9 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFR01390.1 - 0.00099 18.5 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase TNFR_c6 PF00020.18 KFR01391.1 - 1.3e-06 28.6 10.1 3.2e-06 27.4 10.1 1.7 1 0 0 1 1 1 1 TNFR/NGFR cysteine-rich region EGF_CA PF07645.15 KFR01391.1 - 0.0015 18.7 0.3 0.0015 18.7 0.3 2.7 2 1 0 2 2 2 1 Calcium-binding EGF domain Aspzincin_M35 PF14521.6 KFR01391.1 - 0.12 12.9 1.0 0.15 12.6 1.0 1.2 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase RA PF00788.23 KFR01392.1 - 1e-13 51.7 2.5 3.3e-13 50.1 1.1 2.3 1 1 1 2 2 2 1 Ras association (RalGDS/AF-6) domain PH PF00169.29 KFR01392.1 - 1.8e-12 47.7 0.2 4.8e-12 46.3 0.2 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFR01392.1 - 0.0017 18.7 0.2 0.006 17.0 0.2 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain UPF0061 PF02696.14 KFR01393.1 - 4.3e-92 309.3 0.0 4.9e-92 309.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family polyprenyl_synt PF00348.17 KFR01394.1 - 6.6e-71 238.4 0.0 8.1e-71 238.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 KFR01394.1 - 0.001 18.8 0.1 0.0017 18.0 0.1 1.3 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Abi_HHR PF07815.14 KFR01395.1 - 1.3e-34 118.2 0.6 2.5e-34 117.2 0.6 1.5 1 0 0 1 1 1 1 Abl-interactor HHR SH3_1 PF00018.28 KFR01395.1 - 3.5e-09 36.1 0.6 5.7e-09 35.4 0.6 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFR01395.1 - 3.3e-06 26.9 0.1 8.4e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KFR01395.1 - 0.04 13.6 0.1 0.065 12.9 0.1 1.4 1 0 0 1 1 1 0 Variant SH3 domain ACBP PF00887.19 KFR01396.1 - 2.9e-23 81.9 0.1 6.7e-23 80.7 0.1 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein Pkinase PF00069.25 KFR01397.1 - 6.4e-59 199.5 0.0 1.5e-38 132.7 0.3 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFR01397.1 - 2.5e-30 105.6 0.0 3e-23 82.4 0.3 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KFR01397.1 - 0.00031 19.8 0.0 0.00071 18.6 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFR01397.1 - 0.00068 19.6 0.1 0.0054 16.7 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 KFR01397.1 - 0.0037 16.9 0.1 0.5 10.0 0.0 3.0 3 0 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KFR01397.1 - 0.0085 15.4 0.0 0.03 13.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFR01397.1 - 0.0094 15.3 0.5 0.019 14.3 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M41 PF01434.18 KFR01398.1 - 4.8e-65 219.0 2.2 9.3e-65 218.1 2.2 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KFR01398.1 - 2.5e-41 141.2 0.0 7.9e-41 139.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFR01398.1 - 2.4e-08 33.6 0.0 5.5e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KFR01398.1 - 3.8e-05 24.1 0.0 0.00069 20.0 0.0 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KFR01398.1 - 0.00019 21.4 0.0 0.001 19.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KFR01398.1 - 0.00028 20.2 0.2 0.00096 18.4 0.0 2.0 2 0 0 2 2 2 1 TIP49 P-loop domain RuvB_N PF05496.12 KFR01398.1 - 0.00039 20.2 0.0 0.00088 19.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFR01398.1 - 0.00067 20.0 0.0 0.02 15.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KFR01398.1 - 0.0074 16.0 0.0 0.022 14.5 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KFR01398.1 - 0.013 14.9 0.3 0.039 13.3 0.3 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KFR01398.1 - 0.017 15.3 0.0 0.043 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KFR01398.1 - 0.018 15.2 0.0 0.051 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KFR01398.1 - 0.027 13.6 0.0 0.068 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) FumaraseC_C PF10415.9 KFR01398.1 - 0.036 14.5 3.7 0.24 11.9 1.6 3.2 3 0 0 3 3 3 0 Fumarase C C-terminus AAA_18 PF13238.6 KFR01398.1 - 0.038 14.5 0.1 0.18 12.4 0.0 2.2 2 1 0 2 2 1 0 AAA domain AAA_17 PF13207.6 KFR01398.1 - 0.044 14.2 0.0 0.35 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KFR01398.1 - 0.07 12.4 0.0 0.24 10.7 0.0 2.0 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 KFR01398.1 - 0.12 11.9 0.1 0.46 10.0 0.1 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KFR01398.1 - 0.14 12.4 0.2 0.51 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Patched PF02460.18 KFR01399.1 - 5.4e-159 530.9 21.2 6.1e-159 530.7 21.2 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 KFR01399.1 - 7.4e-40 136.3 3.6 7.4e-40 136.3 3.6 2.5 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation KR PF08659.10 KFR01400.1 - 2.2e-54 184.1 0.0 6.5e-54 182.6 0.0 1.9 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KFR01400.1 - 4.5e-49 167.7 0.0 7.5e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFR01400.1 - 9.3e-33 112.7 0.2 3.5e-32 110.9 0.2 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KFR01400.1 - 1.7e-27 96.4 0.0 4.9e-27 95.0 0.0 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KFR01400.1 - 5.5e-14 52.6 0.0 1.6e-13 51.1 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KFR01400.1 - 2.3e-12 46.8 0.1 7.9e-12 45.0 0.1 1.9 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFR01400.1 - 3.2e-07 30.1 0.0 7.2e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.19 KFR01400.1 - 0.065 12.2 0.1 0.53 9.2 0.1 2.5 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Homeobox_KN PF05920.11 KFR01401.1 - 1e-14 54.1 0.3 2e-14 53.2 0.3 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFR01401.1 - 4.3e-05 23.3 1.3 6.3e-05 22.7 0.5 1.7 2 0 0 2 2 2 1 Homeodomain Arm PF00514.23 KFR01402.1 - 9.5e-59 193.8 25.6 6e-05 22.9 0.1 13.4 13 0 0 13 13 13 13 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KFR01402.1 - 3.2e-21 75.5 3.0 1.2e-06 28.8 0.0 7.4 3 3 5 8 8 8 5 HEAT repeats HEAT_EZ PF13513.6 KFR01402.1 - 7.4e-13 48.7 5.4 0.00065 20.2 0.1 8.2 8 1 1 9 9 9 3 HEAT-like repeat Adaptin_N PF01602.20 KFR01402.1 - 8.4e-09 34.5 0.0 9.5e-05 21.1 0.1 3.1 1 1 1 3 3 3 2 Adaptin N terminal region UNC45-central PF11701.8 KFR01402.1 - 3.8e-08 33.4 5.4 0.24 11.4 0.2 4.6 3 1 0 3 3 3 3 Myosin-binding striated muscle assembly central Cnd1 PF12717.7 KFR01402.1 - 6.6e-08 32.8 1.7 0.042 13.9 0.1 4.7 3 1 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 KFR01402.1 - 8.9e-08 32.3 5.6 3.3 7.9 0.5 6.6 5 3 4 9 9 9 1 V-ATPase subunit H HEAT PF02985.22 KFR01402.1 - 3.8e-07 29.8 17.3 0.78 10.2 0.1 8.2 9 0 0 9 9 8 3 HEAT repeat Arm_2 PF04826.13 KFR01402.1 - 3.6e-06 26.6 3.4 9.4 5.6 0.1 6.4 4 2 3 7 7 7 1 Armadillo-like KAP PF05804.12 KFR01402.1 - 4.9e-06 25.0 0.0 0.19 9.8 0.0 3.5 3 1 1 4 4 4 2 Kinesin-associated protein (KAP) WAPL PF07814.13 KFR01402.1 - 4.3e-05 22.5 4.0 0.83 8.4 0.0 4.6 3 1 0 5 5 5 2 Wings apart-like protein regulation of heterochromatin RasGEF_N_2 PF14663.6 KFR01402.1 - 0.00038 20.8 5.9 24 5.4 0.1 6.2 6 1 1 7 7 7 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RTTN_N PF14726.6 KFR01402.1 - 0.029 15.2 1.5 20 6.1 0.0 4.7 5 1 1 6 6 5 0 Rotatin, an armadillo repeat protein, centriole functioning DUF4448 PF14610.6 KFR01402.1 - 0.036 13.8 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Guanylate_kin PF00625.21 KFR01403.1 - 9.7e-51 172.0 0.4 2.9e-49 167.2 0.4 2.3 1 1 0 1 1 1 1 Guanylate kinase L27 PF02828.16 KFR01403.1 - 4.5e-26 90.4 5.8 2.7e-13 49.4 1.4 2.6 2 0 0 2 2 2 2 L27 domain PDZ PF00595.24 KFR01403.1 - 2.4e-12 47.1 0.8 6e-12 45.8 0.8 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFR01403.1 - 8.1e-10 38.4 0.2 4.7e-09 36.0 0.2 2.3 2 0 0 2 2 2 1 PDZ domain SH3_2 PF07653.17 KFR01403.1 - 2e-07 30.6 0.0 5.3e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFR01403.1 - 4.9e-07 29.3 0.4 3.9e-06 26.4 0.2 2.5 2 1 0 2 2 2 1 SH3 domain PDZ_2 PF13180.6 KFR01403.1 - 0.0001 22.6 0.1 0.00036 20.8 0.1 2.0 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.6 KFR01403.1 - 0.0058 16.5 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Tropomyosin PF00261.20 KFR01404.1 - 0.00058 19.3 5.9 0.0007 19.0 5.9 1.1 1 0 0 1 1 1 1 Tropomyosin Filament PF00038.21 KFR01404.1 - 0.0015 18.2 6.3 0.0017 18.0 6.3 1.1 1 0 0 1 1 1 1 Intermediate filament protein DUF2968 PF11180.8 KFR01404.1 - 0.0019 17.9 4.2 0.0023 17.6 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) Seryl_tRNA_N PF02403.22 KFR01404.1 - 0.0021 18.3 7.7 0.037 14.2 0.3 2.1 1 1 1 2 2 2 2 Seryl-tRNA synthetase N-terminal domain Cut8 PF08559.10 KFR01404.1 - 0.0042 16.7 1.7 0.0049 16.5 1.7 1.1 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein TACC_C PF05010.14 KFR01404.1 - 0.0043 16.9 8.8 0.03 14.1 3.9 2.0 1 1 1 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal ADIP PF11559.8 KFR01404.1 - 0.0072 16.4 8.1 0.0087 16.1 8.1 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Baculo_gp41 PF04700.12 KFR01404.1 - 0.013 15.3 0.4 0.015 15.1 0.4 1.1 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region APG6_N PF17675.1 KFR01404.1 - 0.014 15.9 12.3 0.021 15.3 12.3 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region HMMR_N PF15905.5 KFR01404.1 - 0.018 14.6 12.9 0.02 14.4 12.9 1.0 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF3523 PF12037.8 KFR01404.1 - 0.023 14.1 5.2 0.026 13.9 5.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) DUF4140 PF13600.6 KFR01404.1 - 0.033 14.6 0.6 0.033 14.6 0.6 1.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Prefoldin_3 PF13758.6 KFR01404.1 - 0.034 14.2 2.4 0.053 13.6 2.3 1.4 1 1 0 1 1 1 0 Prefoldin subunit TPR_MLP1_2 PF07926.12 KFR01404.1 - 0.036 14.1 11.2 0.13 12.4 9.8 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein UPF0242 PF06785.11 KFR01404.1 - 0.039 14.0 7.2 0.046 13.8 7.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3450 PF11932.8 KFR01404.1 - 0.042 13.2 6.1 0.051 12.9 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF812 PF05667.11 KFR01404.1 - 0.06 12.2 7.8 0.068 12.0 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) GAS PF13851.6 KFR01404.1 - 0.062 12.7 13.1 0.36 10.1 13.1 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIVA PF05103.13 KFR01404.1 - 0.065 13.3 7.4 0.09 12.9 7.4 1.2 1 0 0 1 1 1 0 DivIVA protein Takusan PF04822.13 KFR01404.1 - 0.098 12.6 8.5 1.4 8.8 0.2 2.3 1 1 1 2 2 2 0 Takusan Spc7 PF08317.11 KFR01404.1 - 0.1 11.5 11.7 0.43 9.4 11.4 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein SseC PF04888.12 KFR01404.1 - 0.11 12.1 3.2 0.13 11.8 3.2 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Nup88 PF10168.9 KFR01404.1 - 0.13 10.0 8.0 0.16 9.8 8.0 1.0 1 0 0 1 1 1 0 Nuclear pore component Herpes_UL6 PF01763.16 KFR01404.1 - 0.14 10.7 4.4 0.15 10.5 4.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF5320 PF17253.2 KFR01404.1 - 0.16 13.1 1.6 0.31 12.1 1.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5320) DUF4407 PF14362.6 KFR01404.1 - 0.17 11.2 2.1 0.2 11.0 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 KFR01404.1 - 0.21 11.8 3.2 3 8.2 1.8 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) ZapB PF06005.12 KFR01404.1 - 0.26 11.7 12.5 0.6 10.6 12.5 1.9 1 1 0 1 1 1 0 Cell division protein ZapB DrrA_P4M PF14860.6 KFR01404.1 - 0.28 11.1 6.1 0.33 10.8 4.0 1.9 1 1 1 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain YabA PF06156.13 KFR01404.1 - 0.31 11.7 8.2 0.49 11.1 8.2 1.4 1 1 0 1 1 1 0 Initiation control protein YabA Spore_III_AB PF09548.10 KFR01404.1 - 0.37 10.9 7.0 4.1 7.5 6.6 2.0 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) FapA PF03961.13 KFR01404.1 - 0.4 9.2 6.3 0.42 9.2 6.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMPIT PF07851.13 KFR01404.1 - 0.49 9.6 5.2 0.5 9.6 5.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein Fungal_TACC PF12709.7 KFR01404.1 - 0.56 10.7 9.1 2.2 8.8 6.1 2.7 1 1 2 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins CREPT PF16566.5 KFR01404.1 - 0.59 10.3 8.4 0.97 9.6 7.8 1.5 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour HALZ PF02183.18 KFR01404.1 - 0.59 10.4 9.7 4.6 7.5 3.1 3.3 2 1 1 3 3 3 0 Homeobox associated leucine zipper DUF16 PF01519.16 KFR01404.1 - 0.78 10.3 7.1 1.2 9.6 7.1 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF1664 PF07889.12 KFR01404.1 - 0.95 9.5 5.2 1.5 8.9 5.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) SlyX PF04102.12 KFR01404.1 - 0.96 10.1 7.1 2.3 8.9 6.3 2.0 1 1 1 2 2 2 0 SlyX CENP-H PF05837.12 KFR01404.1 - 1.2 9.5 9.5 1.9 8.9 9.5 1.3 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Lge1 PF11488.8 KFR01404.1 - 1.8 8.8 13.4 3.7 7.8 0.4 2.4 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 Spc24 PF08286.11 KFR01404.1 - 1.9 8.8 8.7 3.1 8.1 8.7 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 TPR_2 PF07719.17 KFR01405.1 - 4.9e-09 35.6 0.1 0.00013 21.8 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFR01405.1 - 2.6e-08 34.4 4.6 4.6e-08 33.6 4.6 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFR01405.1 - 1.7e-07 30.8 0.1 8.2e-05 22.2 0.0 2.2 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.28 KFR01405.1 - 4.8e-06 26.1 0.1 4.4e-05 23.1 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFR01405.1 - 4.3e-05 23.2 3.8 0.00012 21.9 1.8 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFR01405.1 - 7.4e-05 22.8 2.6 0.00021 21.3 1.9 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFR01405.1 - 0.00021 21.5 1.9 0.0062 16.8 0.5 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFR01405.1 - 0.00053 20.4 1.4 0.00089 19.7 1.4 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFR01405.1 - 0.011 16.1 0.1 0.02 15.2 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFR01405.1 - 0.078 13.2 0.0 0.26 11.6 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFR01405.1 - 0.11 13.4 2.8 5.8 8.0 0.5 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFR01405.1 - 0.18 12.5 5.3 0.53 11.1 0.8 3.2 2 2 1 3 3 3 0 Tetratricopeptide repeat IFT46_B_C PF12317.8 KFR01407.1 - 5.3e-98 327.0 0.4 6e-98 326.8 0.4 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal DUF1232 PF06803.12 KFR01407.1 - 0.44 10.4 3.3 0.84 9.5 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1232) Adap_comp_sub PF00928.21 KFR01408.1 - 2e-35 122.4 0.3 2.9e-35 121.9 0.3 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFR01408.1 - 5.8e-06 26.3 0.3 1e-05 25.5 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Dermcidin PF15291.6 KFR01408.1 - 0.086 13.4 0.3 0.16 12.6 0.3 1.5 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide MFS_1 PF07690.16 KFR01409.1 - 4.8e-44 150.7 34.7 5e-44 150.7 29.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_S25 PF03297.15 KFR01410.1 - 5.6e-42 142.0 0.3 6.4e-42 141.9 0.3 1.0 1 0 0 1 1 1 1 S25 ribosomal protein TrmB PF01978.19 KFR01410.1 - 0.041 13.8 0.2 0.074 12.9 0.1 1.5 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 KFR01410.1 - 0.041 14.1 0.1 0.061 13.5 0.1 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain RNA_pol_Rpc34 PF05158.12 KFR01410.1 - 0.046 13.1 0.0 0.05 13.0 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit MarR_2 PF12802.7 KFR01410.1 - 0.055 13.4 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 KFR01410.1 - 0.06 12.9 0.5 0.11 12.1 0.2 1.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding CCDC84 PF14968.6 KFR01411.1 - 1.4e-45 156.5 4.5 1.5e-45 156.3 4.5 1.0 1 0 0 1 1 1 1 Coiled coil protein 84 Forkhead PF00250.18 KFR01412.1 - 1.1e-28 99.2 0.0 1.4e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Forkhead domain DUF3872 PF12988.7 KFR01412.1 - 0.0084 15.9 0.0 0.011 15.5 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function, B. Theta Gene description (DUF3872) HTH_34 PF13601.6 KFR01412.1 - 0.026 14.7 0.0 0.044 14.0 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain DEAD PF00270.29 KFR01415.1 - 1e-41 142.6 1.5 2.5e-41 141.4 0.4 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFR01415.1 - 2.4e-28 98.7 0.7 3.5e-27 94.9 0.5 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KFR01415.1 - 0.0007 19.0 0.2 0.0012 18.2 0.2 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 KFR01415.1 - 0.0013 18.7 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit VPS11_C PF12451.8 KFR01416.1 - 9.7e-19 67.3 0.4 9.7e-19 67.3 0.4 2.8 3 0 0 3 3 2 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.20 KFR01416.1 - 7.5e-15 55.0 11.3 9e-13 48.3 1.5 2.7 2 0 0 2 2 2 2 Region in Clathrin and VPS zf-C3HC4_2 PF13923.6 KFR01416.1 - 3.1e-09 36.5 8.2 6.9e-09 35.4 8.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFR01416.1 - 3.4e-08 33.7 8.8 8.9e-08 32.4 8.8 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFR01416.1 - 3.9e-05 23.8 6.7 0.00012 22.3 6.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFR01416.1 - 0.00014 21.6 8.0 0.00034 20.4 8.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 KFR01416.1 - 0.00089 19.2 9.4 0.0026 17.7 9.4 1.9 1 0 0 1 1 1 1 Zinc-finger zf-RING_5 PF14634.6 KFR01416.1 - 0.0024 17.8 8.3 0.0068 16.3 8.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFR01416.1 - 0.0092 16.0 9.5 0.029 14.4 9.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFR01416.1 - 0.011 15.6 5.2 0.028 14.3 5.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFR01416.1 - 0.063 13.3 2.4 0.21 11.7 2.4 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Paralemmin PF03285.15 KFR01416.1 - 0.072 12.7 0.8 0.13 11.9 0.8 1.4 1 0 0 1 1 1 0 Paralemmin TPR_11 PF13414.6 KFR01416.1 - 0.12 12.0 0.4 1.8 8.3 0.0 3.1 4 0 0 4 4 4 0 TPR repeat zf-C3HC4_4 PF15227.6 KFR01416.1 - 0.14 12.4 9.0 0.47 10.6 9.0 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 KFR01416.1 - 0.22 11.8 7.2 0.77 10.1 7.2 2.0 1 0 0 1 1 1 0 RING-like domain DivIC PF04977.15 KFR01416.1 - 0.23 11.3 3.7 0.72 9.7 3.7 1.8 1 0 0 1 1 1 0 Septum formation initiator zf-RING_11 PF17123.5 KFR01416.1 - 0.28 11.0 8.5 0.79 9.5 8.5 1.9 1 0 0 1 1 1 0 RING-like zinc finger Prefoldin_2 PF01920.20 KFR01416.1 - 1.7 8.6 8.5 12 5.9 4.0 3.2 2 0 0 2 2 2 0 Prefoldin subunit Porphobil_deam PF01379.20 KFR01417.1 - 1.4e-76 256.6 0.0 1.7e-76 256.2 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KFR01417.1 - 7e-20 71.2 0.1 6.7e-19 68.0 0.1 2.3 1 1 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain MGS PF02142.22 KFR01417.1 - 0.033 14.4 0.0 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 MGS-like domain CUE PF02845.16 KFR01417.1 - 0.049 13.3 0.0 5.2 6.9 0.0 2.6 2 0 0 2 2 2 0 CUE domain Glycos_transf_4 PF00953.21 KFR01418.1 - 2.6e-35 121.8 15.7 2.6e-35 121.8 15.7 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 4 Gal_mutarotas_2 PF13802.6 KFR01418.1 - 0.0059 16.9 0.4 0.012 15.9 0.4 1.5 1 0 0 1 1 1 1 Galactose mutarotase-like DUF4133 PF13571.6 KFR01418.1 - 0.044 14.1 1.5 0.044 14.1 1.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) SMP_C2CD2L PF18696.1 KFR01419.1 - 3.8e-41 140.5 0.6 7.5e-41 139.5 0.6 1.5 1 0 0 1 1 1 1 Synaptotagmin-like, mitochondrial and lipid-binding domain C2 PF00168.30 KFR01419.1 - 0.093 13.0 0.0 0.94 9.8 0.0 2.4 3 0 0 3 3 3 0 C2 domain Ras PF00071.22 KFR01446.1 - 1.2e-49 168.0 0.2 1.6e-49 167.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR01446.1 - 5.2e-18 65.4 0.0 9.2e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR01446.1 - 1.8e-07 30.8 0.0 2.6e-07 30.2 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFR01446.1 - 1.1e-05 25.4 1.8 0.031 14.2 0.1 2.2 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFR01446.1 - 0.00029 20.9 0.0 0.0005 20.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFR01446.1 - 0.0012 18.5 0.1 0.0025 17.4 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFR01446.1 - 0.0012 18.3 0.4 0.0025 17.3 0.4 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 KFR01446.1 - 0.0074 16.3 0.1 0.04 13.9 0.0 1.9 1 1 1 2 2 2 1 C-terminal region of MMR_HSR1 domain DUF2408 PF10303.9 KFR01446.1 - 0.028 15.0 1.7 0.67 10.5 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) AAA_24 PF13479.6 KFR01446.1 - 0.033 13.9 0.3 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KFR01446.1 - 0.038 13.0 0.2 2.7 6.9 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KFR01446.1 - 0.053 13.9 0.1 0.067 13.6 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain NYAP_N PF15439.6 KFR01446.1 - 0.063 12.5 0.1 0.074 12.3 0.1 1.1 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter AAA_22 PF13401.6 KFR01446.1 - 0.086 13.1 0.5 0.71 10.1 0.5 2.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFR01446.1 - 0.12 12.6 0.1 0.31 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain Zip PF02535.22 KFR01447.1 - 1.8e-48 165.5 13.4 5.6e-48 163.9 13.4 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter TPR_1 PF00515.28 KFR01448.1 - 3.3e-27 93.1 7.1 3.4e-10 39.3 0.0 3.6 4 0 0 4 4 3 3 Tetratricopeptide repeat SGTA_dimer PF16546.5 KFR01448.1 - 1.4e-22 79.3 0.7 5.7e-22 77.3 0.1 2.1 2 0 0 2 2 2 1 Homodimerisation domain of SGTA TPR_2 PF07719.17 KFR01448.1 - 5.9e-20 69.7 5.3 4.9e-06 26.2 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFR01448.1 - 2.3e-19 67.9 3.5 2e-07 30.6 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFR01448.1 - 1e-16 60.3 6.4 1.1e-06 28.2 0.3 4.1 2 1 2 4 4 4 3 TPR repeat TPR_17 PF13431.6 KFR01448.1 - 1.8e-14 53.0 3.5 1.7e-06 28.0 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFR01448.1 - 4.5e-12 45.1 0.3 0.0011 18.8 0.0 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFR01448.1 - 3.4e-10 39.9 0.1 0.017 15.9 0.0 4.2 3 1 2 5 5 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFR01448.1 - 6.7e-10 39.5 1.3 1.8e-05 25.3 0.1 2.6 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFR01448.1 - 4.9e-09 36.3 2.1 5e-07 29.9 0.3 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFR01448.1 - 1.3e-08 34.4 2.6 0.009 15.9 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFR01448.1 - 2e-08 34.6 2.6 2.3e-05 24.8 0.0 3.3 3 1 1 4 4 3 2 Tetratricopeptide repeat TOM20_plant PF06552.12 KFR01448.1 - 5.8e-05 22.9 0.8 0.28 10.9 0.1 3.0 2 1 0 2 2 2 2 Plant specific mitochondrial import receptor subunit TOM20 TPR_9 PF13371.6 KFR01448.1 - 7.1e-05 22.9 0.0 0.0015 18.6 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFR01448.1 - 0.00019 21.8 0.7 1.2 10.0 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFR01448.1 - 0.00027 20.9 6.4 0.051 13.7 0.1 3.5 3 1 2 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.8 KFR01448.1 - 0.0024 16.8 0.4 1.5 7.7 0.4 2.2 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 DUF627 PF04781.12 KFR01448.1 - 0.0043 17.1 0.2 0.15 12.1 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF627) TPR_15 PF13429.6 KFR01448.1 - 0.0063 15.8 0.0 1.5 7.9 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.17 KFR01448.1 - 0.0087 16.5 0.8 0.46 10.9 0.1 2.5 2 1 0 3 3 2 1 Bacterial transcriptional activator domain MIT PF04212.18 KFR01448.1 - 0.036 14.1 6.5 12 6.0 0.0 4.3 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain XPC-binding PF09280.11 KFR01448.1 - 0.13 12.0 9.6 0.9 9.3 3.7 2.7 2 0 0 2 2 2 0 XPC-binding domain TrbI PF03743.14 KFR01448.1 - 0.25 11.2 3.4 0.37 10.6 3.4 1.4 1 1 0 1 1 1 0 Bacterial conjugation TrbI-like protein STI1 PF17830.1 KFR01448.1 - 0.54 10.2 5.3 0.35 10.8 0.6 2.6 2 0 0 2 2 2 0 STI1 domain Peptidase_M3 PF01432.20 KFR01449.1 - 2.9e-164 547.7 0.1 3.7e-164 547.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M3 CdvA PF18822.1 KFR01449.1 - 0.23 11.3 3.9 0.12 12.2 1.0 1.9 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DUF4085 PF13315.6 KFR01449.1 - 0.61 9.7 3.8 0.13 11.9 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4085) NTR PF01759.21 KFR01450.1 - 1.4e-11 44.2 0.0 1.6e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Peptidase_S8 PF00082.22 KFR01451.1 - 3.6e-36 125.0 0.6 5e-36 124.5 0.6 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KFR01451.1 - 3.7e-27 94.2 0.1 6.6e-27 93.4 0.1 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KFR01451.1 - 4.6e-09 36.9 4.4 8.1e-09 36.1 3.3 2.1 2 0 0 2 2 2 1 Peptidase S8 pro-domain TB2_DP1_HVA22 PF03134.19 KFR01452.1 - 6.7e-28 96.4 4.7 7.8e-28 96.2 4.7 1.1 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Ribosomal_S19 PF00203.21 KFR01453.1 - 4.6e-40 135.4 0.3 6.4e-40 134.9 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 MAP65_ASE1 PF03999.12 KFR01453.1 - 0.015 14.1 0.9 0.017 13.9 0.9 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Corazonin PF17308.2 KFR01453.1 - 0.062 13.7 0.1 0.08 13.3 0.1 1.1 1 0 0 1 1 1 0 Pro-corazonin Prok_Ub PF14454.6 KFR01453.1 - 0.16 11.7 0.1 0.42 10.3 0.1 1.7 1 0 0 1 1 1 0 Prokaryotic Ubiquitin RRM_1 PF00076.22 KFR01454.1 - 7.7e-37 125.0 0.2 8.8e-18 63.9 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFR01454.1 - 3.8e-13 49.4 0.3 2.3e-07 30.8 0.1 2.5 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KFR01454.1 - 1.5e-05 24.9 0.2 0.062 13.3 0.1 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KFR01454.1 - 0.0003 21.1 0.2 0.54 10.5 0.0 3.0 2 2 1 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter CSD PF00313.22 KFR01454.1 - 0.029 14.2 1.1 1.5 8.8 0.1 2.3 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain DUF4651 PF15513.6 KFR01454.1 - 0.16 11.8 0.2 7.3 6.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) Oxidored_q6 PF01058.22 KFR01455.1 - 8.2e-07 28.9 0.2 0.0007 19.4 0.0 2.1 1 1 0 2 2 2 2 NADH ubiquinone oxidoreductase, 20 Kd subunit DIL PF01843.19 KFR01455.1 - 0.14 12.4 0.0 0.22 11.8 0.0 1.5 1 1 0 1 1 1 0 DIL domain PWWP PF00855.17 KFR01456.1 - 2.4e-10 40.7 0.1 1.2e-05 25.6 0.0 3.3 2 0 0 2 2 2 2 PWWP domain DUF4441 PF14536.6 KFR01456.1 - 0.016 15.4 0.2 0.016 15.4 0.2 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4441) TrmK PF04816.12 KFR01456.1 - 0.19 11.2 2.6 1.9 8.0 0.4 2.4 1 1 1 2 2 2 0 tRNA (adenine(22)-N(1))-methyltransferase Pkinase PF00069.25 KFR01457.1 - 2e-60 204.4 0.0 2.3e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR01457.1 - 2.1e-20 73.1 0.0 2.5e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR01457.1 - 7.3e-05 22.2 0.0 0.00011 21.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFR01457.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KFR01457.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Ephrin PF00812.17 KFR01458.1 - 5.6e-35 120.3 0.1 6.3e-35 120.2 0.1 1.0 1 0 0 1 1 1 1 Ephrin RRM_1 PF00076.22 KFR01459.1 - 4.7e-26 90.4 0.1 7.4e-26 89.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFR01459.1 - 0.00015 21.8 0.1 0.00029 20.9 0.1 1.5 1 1 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 KFR01459.1 - 0.00043 20.1 0.0 0.00089 19.1 0.0 1.4 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KFR01459.1 - 0.078 13.0 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 RNA binding motif RRM_5 PF13893.6 KFR01459.1 - 0.084 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.11 KFR01459.1 - 0.52 9.0 2.7 0.67 8.7 2.7 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF3540 PF12059.8 KFR01460.1 - 0.044 13.6 3.9 0.052 13.4 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3540) Pkinase PF00069.25 KFR01461.1 - 4.1e-54 183.7 0.0 5.1e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR01461.1 - 2e-32 112.5 0.0 3e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR01461.1 - 5.3e-11 42.4 0.0 1.2e-10 41.3 0.0 1.6 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFR01461.1 - 0.005 15.7 0.5 0.012 14.4 0.0 1.8 3 0 0 3 3 3 1 Fungal protein kinase Kdo PF06293.14 KFR01461.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFR01461.1 - 0.1 12.5 0.0 0.75 9.7 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family GSHPx PF00255.19 KFR01462.1 - 2.9e-08 33.2 0.0 3.4e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KFR01462.1 - 0.051 13.5 0.0 0.051 13.5 0.0 1.1 1 0 0 1 1 1 0 AhpC/TSA family RNA_pol_Rpb5_C PF01191.19 KFR01463.1 - 4e-35 119.5 0.2 7.1e-35 118.7 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KFR01463.1 - 2.1e-18 66.6 0.0 4.1e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain RhoGAP PF00620.27 KFR01464.1 - 2.1e-50 170.5 0.0 5.3e-50 169.2 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 KFR01464.1 - 1.3e-06 28.2 9.6 2.6e-06 27.2 9.6 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) REV1_C PF16727.5 KFR01464.1 - 0.22 11.9 2.2 0.89 10.0 0.0 3.0 4 0 0 4 4 4 0 DNA repair protein REV1 C-terminal domain HDV_ag PF01517.18 KFR01464.1 - 1.5 8.6 7.0 5.7 6.7 7.0 2.0 1 1 0 1 1 1 0 Hepatitis delta virus delta antigen SLC12 PF03522.15 KFR01464.1 - 4.2 6.3 12.8 7.9 5.4 12.8 1.3 1 0 0 1 1 1 0 Solute carrier family 12 zf-RING-like PF08746.11 KFR01464.1 - 4.8 7.6 9.9 13 6.2 9.9 1.7 1 0 0 1 1 1 0 RING-like domain Calponin PF00402.18 KFR01465.1 - 1e-40 137.0 30.9 2.2e-16 59.1 1.6 4.8 5 0 0 5 5 5 3 Calponin family repeat CH PF00307.31 KFR01465.1 - 4e-23 81.7 0.1 6.7e-23 81.0 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFR01465.1 - 0.00079 19.2 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain CDC24 PF06395.11 KFR01465.1 - 0.14 12.4 0.1 0.24 11.7 0.1 1.3 1 0 0 1 1 1 0 CDC24 Calponin ABC2_membrane_3 PF12698.7 KFR01466.1 - 7.9e-62 209.4 35.1 7.4e-46 156.8 10.6 2.8 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.27 KFR01466.1 - 4.3e-41 140.6 0.0 3.5e-21 76.2 0.0 2.8 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KFR01466.1 - 4.2e-19 69.5 0.0 1.4e-07 31.6 0.0 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFR01466.1 - 0.003 18.1 2.7 0.033 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KFR01466.1 - 0.014 15.1 0.0 4.2 7.0 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.6 KFR01466.1 - 0.037 13.8 1.0 0.45 10.3 0.3 2.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain SRP54 PF00448.22 KFR01466.1 - 0.59 9.7 2.6 5.8 6.5 0.1 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MukB PF04310.12 KFR01466.1 - 0.67 9.7 1.6 0.79 9.5 0.1 1.8 2 0 0 2 2 2 0 MukB N-terminal Membralin PF09746.9 KFR01467.1 - 2.4e-173 576.6 7.1 4e-173 575.8 7.1 1.3 1 0 0 1 1 1 1 Tumour-associated protein HalX PF08663.10 KFR01468.1 - 0.032 14.5 0.3 0.043 14.1 0.3 1.3 1 0 0 1 1 1 0 HalX domain WD40 PF00400.32 KFR01469.1 - 1.1e-22 79.8 5.5 1.1e-09 38.8 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat WD40_alt PF14077.6 KFR01469.1 - 3.1e-20 71.8 0.5 5.3e-20 71.0 0.5 1.4 1 0 0 1 1 1 1 Alternative WD40 repeat motif ANAPC4_WD40 PF12894.7 KFR01469.1 - 1.1e-05 25.6 0.0 0.0012 19.1 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFR01469.1 - 0.0058 15.3 0.3 0.03 13.0 0.1 1.9 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFR01469.1 - 0.097 11.6 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TFIIA PF03153.13 KFR01470.1 - 0.18 11.8 28.0 0.22 11.5 28.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Caldesmon PF02029.15 KFR01470.1 - 0.21 10.3 23.9 0.27 10.0 23.9 1.2 1 0 0 1 1 1 0 Caldesmon SpoIIIAH PF12685.7 KFR01470.1 - 3 7.6 11.8 0.61 9.9 8.0 1.7 2 0 0 2 2 2 0 SpoIIIAH-like protein R3H-assoc PF13902.6 KFR01471.1 - 2.4e-32 112.1 0.9 3.7e-32 111.5 0.9 1.2 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 KFR01471.1 - 8.3e-06 25.7 0.0 2.1e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 R3H domain PDCD2_C PF04194.13 KFR01471.1 - 0.068 13.2 0.3 0.088 12.9 0.3 1.2 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain Med16 PF11635.8 KFR01472.1 - 6.8e-136 454.2 0.1 8.7e-136 453.8 0.1 1.1 1 0 0 1 1 1 1 Mediator complex subunit 16 WD40 PF00400.32 KFR01472.1 - 0.00015 22.5 5.1 0.00029 21.6 1.6 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR01472.1 - 0.00039 20.6 0.2 0.088 13.1 0.2 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PAP2 PF01569.21 KFR01473.1 - 3.5e-13 49.5 4.3 6.4e-13 48.7 4.3 1.3 1 0 0 1 1 1 1 PAP2 superfamily RRM_5 PF13893.6 KFR01474.1 - 7.2e-62 206.6 0.7 1.7e-43 147.2 0.0 4.1 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KFR01474.1 - 3e-38 129.5 0.3 8.7e-11 41.5 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KFR01474.1 - 3.7e-15 55.9 0.0 4.3e-14 52.5 0.0 2.2 2 0 0 2 2 2 1 RRM-like domain RRM_occluded PF16842.5 KFR01474.1 - 1.4e-11 44.0 0.4 0.07 13.0 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif AKAP2_C PF15304.6 KFR01475.1 - 2.4e-36 125.8 35.7 1.1e-19 70.9 12.9 6.1 4 2 0 4 4 4 3 A-kinase anchor protein 2 C-terminus zf-RING_2 PF13639.6 KFR01476.1 - 8.5e-14 51.6 7.4 8.5e-14 51.6 7.4 1.6 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFR01476.1 - 2.7e-09 36.7 7.1 2.7e-09 36.7 7.1 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFR01476.1 - 1.3e-08 34.4 1.7 1.3e-08 34.4 1.7 1.8 2 0 0 2 2 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KFR01476.1 - 1.4e-07 31.7 8.3 1.4e-07 31.7 8.3 2.0 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFR01476.1 - 1.5e-07 31.3 5.1 1.9e-07 31.0 2.8 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFR01476.1 - 3.7e-07 29.9 6.6 3.7e-07 29.9 6.6 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFR01476.1 - 1.5e-06 28.0 5.6 1.5e-06 28.0 5.6 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFR01476.1 - 1.7e-06 27.7 2.9 1.7e-06 27.7 2.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFR01476.1 - 6.9e-05 22.8 3.7 0.00017 21.5 3.7 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KFR01476.1 - 0.00012 21.8 8.6 0.00012 21.8 8.6 2.5 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KFR01476.1 - 0.0023 17.5 4.2 0.0057 16.3 4.2 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 KFR01476.1 - 0.0033 17.2 3.7 0.0078 16.0 3.7 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zinc_ribbon_9 PF14369.6 KFR01476.1 - 0.0062 16.8 0.5 0.0062 16.8 0.5 3.1 3 0 0 3 3 3 1 zinc-ribbon Vps39_2 PF10367.9 KFR01476.1 - 0.013 15.9 1.0 2.7 8.5 0.5 2.3 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 DUF3678 PF12435.8 KFR01476.1 - 0.016 14.6 0.2 0.016 14.6 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Rad50_zn_hook PF04423.14 KFR01476.1 - 0.087 12.7 4.9 0.54 10.1 0.0 3.1 3 0 0 3 3 3 0 Rad50 zinc hook motif DUF983 PF06170.12 KFR01476.1 - 0.1 13.0 0.1 4.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF983) RINGv PF12906.7 KFR01476.1 - 0.43 10.7 4.5 0.9 9.7 4.5 1.6 1 1 0 1 1 1 0 RING-variant domain Opy2 PF09463.10 KFR01476.1 - 0.52 10.7 4.5 34 4.9 0.1 3.3 3 0 0 3 3 3 0 Opy2 protein PHD PF00628.29 KFR01476.1 - 1.3 8.9 9.9 1.5 8.7 5.4 2.5 2 0 0 2 2 2 0 PHD-finger FANCL_C PF11793.8 KFR01476.1 - 2.8 8.2 8.4 50 4.2 8.4 2.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KFR01476.1 - 3.6 7.5 11.7 6.2 6.7 0.2 2.9 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KFR01476.1 - 5.7 7.2 11.0 5.5 7.2 7.5 2.7 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 KFR01476.1 - 6.1 7.2 12.8 0.061 13.6 5.2 1.6 2 0 0 2 2 1 0 RING-like domain IMUP PF15761.5 KFR01476.1 - 7.1 7.4 11.7 11 6.8 7.1 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein zf-H2C2_2 PF13465.6 KFR01476.1 - 7.1 7.2 6.0 42 4.8 0.1 3.0 3 0 0 3 3 2 0 Zinc-finger double domain FGF PF00167.18 KFR01477.1 - 3.5e-35 120.8 0.0 3.9e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor RNA_pol PF00940.19 KFR01479.1 - 8.3e-160 532.1 0.0 1.2e-159 531.7 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KFR01479.1 - 8.7e-55 186.4 0.0 1.4e-54 185.8 0.0 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal PPR_3 PF13812.6 KFR01479.1 - 0.0076 16.3 0.0 0.021 14.9 0.0 1.9 1 0 0 1 1 1 1 Pentatricopeptide repeat domain Exog_C PF18026.1 KFR01479.1 - 0.014 15.5 0.7 0.1 12.6 0.9 2.5 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain PPR_2 PF13041.6 KFR01479.1 - 0.023 14.9 0.0 0.11 12.8 0.0 2.2 2 0 0 2 2 2 0 PPR repeat family Histone_HNS PF00816.21 KFR01479.1 - 0.099 13.5 0.1 1 10.2 0.0 2.6 2 0 0 2 2 2 0 H-NS histone family Ion_trans PF00520.31 KFR01480.1 - 2.1e-22 79.6 16.5 3.2e-22 79.0 16.5 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KFR01480.1 - 1.4e-18 66.7 0.0 2.9e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KFR01480.1 - 0.0015 18.5 0.2 0.0064 16.4 0.2 2.1 2 0 0 2 2 2 1 Ion channel Rib_recp_KP_reg PF05104.12 KFR01480.1 - 0.41 11.7 5.9 0.6 11.1 5.9 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region UQ_con PF00179.26 KFR01481.1 - 2.8e-43 146.9 0.0 3.7e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFR01481.1 - 0.024 14.4 0.0 0.07 12.8 0.0 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B MFS_1 PF07690.16 KFR01482.1 - 5.8e-34 117.6 38.0 2.1e-33 115.7 37.7 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KFR01482.1 - 2.4e-11 43.1 24.5 3.2e-08 32.8 24.5 3.2 1 1 0 1 1 1 1 MFS_1 like family PID PF00640.23 KFR01483.1 - 2e-30 105.7 0.0 2.9e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.24 KFR01483.1 - 3.1e-18 65.6 0.0 5.1e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 SH2 domain C2 PF00168.30 KFR01484.1 - 1e-09 38.6 0.0 1.7e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain ELM2 PF01448.24 KFR01485.1 - 7e-11 42.7 1.8 1.8e-10 41.4 0.1 2.6 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-binding PF00249.31 KFR01485.1 - 8.8e-07 29.0 1.9 1.1e-06 28.7 0.6 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF2002 PF09400.10 KFR01485.1 - 0.05 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2002) SMN PF06003.12 KFR01485.1 - 7.1 5.8 15.3 2.7 7.2 0.6 3.5 3 1 1 4 4 4 0 Survival motor neuron protein (SMN) PAP2 PF01569.21 KFR01486.1 - 1.1e-25 89.9 4.0 1.1e-25 89.9 4.0 1.5 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KFR01486.1 - 0.015 15.8 2.6 0.015 15.8 2.6 2.4 2 1 0 2 2 2 0 PAP2 superfamily C-terminal DUF2976 PF11190.8 KFR01486.1 - 0.38 10.6 2.6 0.35 10.7 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) TLE_N PF03920.15 KFR01487.1 - 3.2e-65 218.1 11.3 4.2e-65 217.7 11.3 1.2 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain AA_kinase PF00696.28 KFR01487.1 - 0.034 13.8 0.0 0.059 13.0 0.0 1.4 1 1 0 1 1 1 0 Amino acid kinase family HALZ PF02183.18 KFR01487.1 - 0.036 14.3 0.2 0.078 13.2 0.2 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper SKA2 PF16740.5 KFR01487.1 - 1.3 8.8 6.6 2 8.2 2.5 2.3 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 TLE_N PF03920.15 KFR01488.1 - 1.2e-66 222.7 9.9 1.9e-66 222.1 9.9 1.3 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.32 KFR01488.1 - 4.1e-12 46.4 19.3 0.006 17.4 0.4 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR01488.1 - 6e-05 23.3 0.0 1.2 9.5 0.0 3.9 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain HALZ PF02183.18 KFR01488.1 - 0.011 16.0 0.9 0.031 14.5 0.9 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper WD40_like PF17005.5 KFR01488.1 - 0.19 11.0 0.0 6.7 5.9 0.1 2.2 2 0 0 2 2 2 0 WD40-like domain G-alpha PF00503.20 KFR01489.1 - 1.1e-108 363.6 1.8 1.2e-108 363.5 1.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFR01489.1 - 5.4e-12 45.5 0.6 2.7e-11 43.2 0.2 2.2 2 1 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFR01489.1 - 0.11 12.6 0.1 1.6 8.8 0.1 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase Trypsin PF00089.26 KFR01490.1 - 3e-26 92.6 0.0 1.8e-18 67.1 0.0 2.0 1 1 1 2 2 2 2 Trypsin DUF1986 PF09342.11 KFR01490.1 - 0.021 15.2 0.0 0.03 14.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Trypsin PF00089.26 KFR01491.1 - 2.2e-64 217.3 0.1 2.5e-64 217.1 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFR01491.1 - 3.9e-06 27.8 0.0 9e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFR01491.1 - 0.13 12.6 0.1 0.55 10.6 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1986) Peptidase_M28 PF04389.17 KFR01492.1 - 2e-12 47.2 0.0 3.8e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.15 KFR01492.1 - 1.5e-06 27.8 0.0 2.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Nicastrin RRM_1 PF00076.22 KFR01493.1 - 6.9e-38 128.3 0.0 3.4e-17 62.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFR01493.1 - 0.0066 16.4 0.0 1.5 8.8 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KFR01493.1 - 0.077 13.2 0.2 18 5.5 0.0 2.5 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter NOP5NT PF08156.13 KFR01493.1 - 0.22 12.0 0.5 52 4.3 0.1 3.1 3 0 0 3 3 3 0 NOP5NT (NUC127) domain adh_short PF00106.25 KFR01494.1 - 9.2e-32 110.1 0.1 3e-30 105.1 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFR01494.1 - 3.7e-17 62.7 0.1 8.9e-12 45.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KFR01494.1 - 0.00013 21.5 0.0 0.00017 21.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KFR01494.1 - 0.00039 20.4 0.1 0.18 11.7 0.1 2.2 2 0 0 2 2 2 2 KR domain SE PF08491.10 KFR01494.1 - 0.0083 15.2 0.0 0.034 13.2 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase QIL1 PF15884.5 KFR01495.1 - 3.2e-27 94.9 0.0 3.8e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 MICOS complex subunit MIC13, QIL1 Morc6_S5 PF17942.1 KFR01499.1 - 9.8e-24 84.0 0.8 1.8e-16 60.4 0.0 2.5 2 0 0 2 2 2 2 Morc6 ribosomal protein S5 domain 2-like zf-CW PF07496.15 KFR01499.1 - 8.1e-15 54.6 4.0 1.9e-14 53.4 4.0 1.7 1 0 0 1 1 1 1 CW-type Zinc Finger HATPase_c_3 PF13589.6 KFR01499.1 - 6.8e-10 38.9 0.7 1.5e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase XhlA PF10779.9 KFR01499.1 - 2.6 8.3 16.9 2.9 8.2 0.8 3.8 3 0 0 3 3 3 0 Haemolysin XhlA SKICH PF17751.1 KFR01500.1 - 2.3e-28 98.7 0.3 5.3e-28 97.6 0.3 1.6 1 0 0 1 1 1 1 SKICH domain Exo_endo_phos PF03372.23 KFR01500.1 - 4.2e-12 46.1 0.0 6.4e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HECW_N PF16562.5 KFR01500.1 - 0.043 13.6 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 DUF1156 PF06634.12 KFR01500.1 - 0.11 12.7 0.0 0.4 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1156) Phospholip_A2_2 PF05826.12 KFR01501.1 - 7.4e-06 26.1 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Phospholipase A2 HEAT_EZ PF13513.6 KFR01514.1 - 1.6e-28 98.7 0.9 2.9e-12 46.8 0.0 7.5 8 1 2 10 10 8 3 HEAT-like repeat HEAT PF02985.22 KFR01514.1 - 4.5e-27 91.8 5.7 0.0015 18.6 0.0 9.1 9 0 0 9 9 9 6 HEAT repeat HEAT_2 PF13646.6 KFR01514.1 - 1.1e-21 77.1 0.2 2.9e-06 27.6 0.0 5.1 3 2 3 6 6 6 6 HEAT repeats Arm PF00514.23 KFR01514.1 - 8.1e-14 51.1 4.0 0.0036 17.3 0.0 6.3 7 0 0 7 7 6 2 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 KFR01514.1 - 1.2e-11 45.0 1.1 0.00055 20.5 0.1 4.6 2 2 3 5 5 5 5 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KFR01514.1 - 1.7e-11 44.5 0.1 0.00018 21.6 0.3 3.3 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KFR01514.1 - 8.6e-10 37.8 4.6 0.0068 15.0 0.2 4.1 2 2 1 3 3 3 3 Adaptin N terminal region Xpo1 PF08389.12 KFR01514.1 - 0.00027 21.0 1.3 2 8.4 0.0 4.0 2 1 1 3 3 3 1 Exportin 1-like protein RTP1_C1 PF10363.9 KFR01514.1 - 0.00035 20.7 0.0 0.031 14.5 0.1 3.2 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 UNC45-central PF11701.8 KFR01514.1 - 0.00039 20.4 1.0 0.0035 17.3 0.2 2.6 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central Dopey_N PF04118.14 KFR01514.1 - 0.00099 18.3 1.4 0.0017 17.5 0.1 1.9 2 1 0 2 2 2 1 Dopey, N-terminal MMS19_C PF12460.8 KFR01514.1 - 0.0016 17.7 3.8 0.21 10.6 0.1 3.8 3 2 1 4 4 4 2 RNAPII transcription regulator C-terminal IBN_N PF03810.19 KFR01514.1 - 0.0021 18.0 0.0 0.0067 16.3 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain CLASP_N PF12348.8 KFR01514.1 - 0.005 16.4 0.1 0.47 10.0 0.0 2.9 2 1 0 2 2 2 1 CLASP N terminal TAFH PF07531.14 KFR01514.1 - 0.0095 16.0 1.2 6 7.0 0.0 4.0 3 1 1 4 4 4 1 NHR1 homology to TAF DUF3437 PF11919.8 KFR01514.1 - 0.075 13.0 0.1 3 7.8 0.0 3.4 2 2 2 4 4 4 0 Domain of unknown function (DUF3437) Yae1_N PF09811.9 KFR01523.1 - 3.2e-08 33.1 30.5 0.31 10.8 22.0 4.5 2 2 0 2 2 2 2 Essential protein Yae1, N terminal DUF4816 PF16086.5 KFR01523.1 - 6.1 6.8 9.5 49 3.9 9.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4816) CaMBD PF02888.16 KFR01524.1 - 7.5e-39 131.8 12.3 1.8e-38 130.6 10.7 2.2 2 0 0 2 2 2 1 Calmodulin binding domain SK_channel PF03530.14 KFR01524.1 - 4.7e-30 103.9 0.7 4.7e-30 103.9 0.7 2.6 2 0 0 2 2 2 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.16 KFR01524.1 - 8.9e-14 51.2 3.2 3.1e-13 49.5 3.2 1.9 1 0 0 1 1 1 1 Ion channel Med9 PF07544.13 KFR01524.1 - 0.0036 17.4 2.2 0.0038 17.3 0.6 1.8 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 IRK PF01007.20 KFR01524.1 - 0.18 11.6 5.0 0.17 11.7 2.4 2.2 2 1 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain SlyX PF04102.12 KFR01524.1 - 0.41 11.3 3.8 0.41 11.3 0.1 2.5 2 0 0 2 2 2 0 SlyX Prefoldin_2 PF01920.20 KFR01524.1 - 1.4 8.9 11.8 14 5.7 6.6 3.3 1 1 2 3 3 3 0 Prefoldin subunit zf-RING_UBOX PF13445.6 KFR01525.1 - 2.4e-08 33.9 2.8 2.4e-08 33.9 2.8 3.2 3 0 0 3 3 3 1 RING-type zinc-finger zf-B_box PF00643.24 KFR01525.1 - 5.9e-07 29.5 35.0 4.3e-06 26.8 6.9 4.1 3 1 0 3 3 3 2 B-box zinc finger zf-C3HC4 PF00097.25 KFR01525.1 - 9.7e-06 25.4 4.5 9.7e-06 25.4 4.5 3.9 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFR01525.1 - 2.3e-05 24.4 4.8 2.3e-05 24.4 4.8 4.2 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING fn3 PF00041.21 KFR01525.1 - 2.9e-05 24.3 0.0 6.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain zf-C3HC4_3 PF13920.6 KFR01525.1 - 0.00029 20.6 4.3 0.00029 20.6 4.3 4.9 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFR01525.1 - 0.0042 17.0 3.5 0.0042 17.0 3.5 4.6 4 1 0 4 4 4 1 zinc-RING finger domain SPRY PF00622.28 KFR01525.1 - 0.059 13.5 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 SPRY domain Phasin PF05597.11 KFR01525.1 - 0.061 13.3 3.5 0.13 12.2 3.1 1.8 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4200 PF13863.6 KFR01525.1 - 3.4 8.1 11.9 3 8.3 9.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Baculo_PEP_C PF04513.12 KFR01526.1 - 0.082 12.9 1.9 0.15 12.1 1.9 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 KFR01526.1 - 0.13 12.8 1.7 0.28 11.7 1.7 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Arm-DNA-bind_2 PF12167.8 KFR01526.1 - 0.35 10.8 3.6 0.82 9.6 0.0 2.9 3 0 0 3 3 3 0 Arm DNA-binding domain Ank_2 PF12796.7 KFR01527.1 - 1.3e-39 134.7 8.3 2.8e-19 69.5 1.1 4.5 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFR01527.1 - 1.1e-33 115.2 3.0 6.1e-11 42.6 0.1 5.9 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KFR01527.1 - 1.1e-31 107.9 13.2 1.3e-05 25.4 0.0 8.1 7 1 0 7 7 7 7 Ankyrin repeat Ank_3 PF13606.6 KFR01527.1 - 1.4e-30 101.8 6.7 0.00012 22.2 0.0 8.8 7 1 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.6 KFR01527.1 - 2.5e-29 100.9 5.6 3.9e-09 36.6 0.3 6.1 3 1 3 6 6 6 4 Ankyrin repeats (many copies) TPR_12 PF13424.6 KFR01527.1 - 2.2e-05 24.7 0.0 0.1 12.9 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFR01527.1 - 0.018 15.1 0.6 0.39 10.9 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFR01527.1 - 0.031 14.1 0.2 0.39 10.7 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Cnd1 PF12717.7 KFR01527.1 - 0.067 13.2 0.3 1.2 9.1 0.0 2.9 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Aldedh PF00171.22 KFR01528.1 - 4.9e-126 420.9 0.0 5.5e-126 420.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.6 KFR01528.1 - 0.073 13.1 0.3 0.26 11.3 0.1 1.9 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated GRAM PF02893.20 KFR01529.1 - 3.1e-18 65.7 0.2 7e-18 64.6 0.2 1.6 1 0 0 1 1 1 1 GRAM domain Plasmodium_Vir PF05795.11 KFR01529.1 - 0.0083 15.6 0.2 0.016 14.6 0.2 1.4 1 0 0 1 1 1 1 Plasmodium vivax Vir protein eRF1_1 PF03463.15 KFR01549.1 - 2.5e-52 176.3 0.1 4e-52 175.6 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 KFR01549.1 - 7.6e-35 120.1 0.1 1.3e-34 119.4 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KFR01549.1 - 3.2e-26 92.0 0.1 9.1e-26 90.6 0.0 1.8 2 0 0 2 2 2 1 eRF1 domain 3 LEDGF PF11467.8 KFR01561.1 - 3.7e-28 97.6 5.5 3.7e-28 97.6 5.5 2.5 3 0 0 3 3 3 1 Lens epithelium-derived growth factor (LEDGF) PWWP PF00855.17 KFR01561.1 - 0.0027 18.1 0.0 0.0027 18.1 0.0 4.2 2 1 0 3 3 3 1 PWWP domain zf-SNAP50_C PF12251.8 KFR01562.1 - 4.8e-76 254.9 3.7 6e-76 254.6 3.7 1.1 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal DUF3808 PF10300.9 KFR01563.1 - 1.2e-167 558.4 12.1 1.5e-167 558.1 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_12 PF13424.6 KFR01563.1 - 2.7e-10 40.4 6.0 4.9e-05 23.6 0.2 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFR01563.1 - 8.1e-07 28.6 6.1 0.038 13.8 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFR01563.1 - 1.2e-06 28.1 12.9 0.021 14.9 0.5 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFR01563.1 - 0.0064 16.4 5.2 0.11 12.6 0.3 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFR01563.1 - 0.037 14.3 7.4 0.2 12.0 0.8 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4810 PF16068.5 KFR01563.1 - 0.1 13.2 1.9 0.25 11.9 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4810) TPR_6 PF13174.6 KFR01563.1 - 0.13 13.0 0.6 0.13 13.0 0.6 6.4 8 1 0 8 8 7 0 Tetratricopeptide repeat SOAR PF16533.5 KFR01563.1 - 0.32 11.0 4.5 1.2 9.2 1.1 2.7 2 0 0 2 2 2 0 STIM1 Orai1-activating region TPR_10 PF13374.6 KFR01563.1 - 0.68 9.9 6.4 2.7 8.0 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFR01563.1 - 3.4 8.2 12.6 1.8 9.1 0.0 5.5 7 0 0 7 7 7 0 Tetratricopeptide repeat Cadherin_3 PF16184.5 KFR01564.1 - 6.4e-237 769.9 19.4 5.1e-28 97.3 0.0 13.6 13 1 0 13 13 13 12 Cadherin-like Cadherin_4 PF17803.1 KFR01564.1 - 4.8e-15 55.9 0.4 0.024 15.3 0.4 8.9 8 0 0 8 8 8 3 Bacterial cadherin-like domain Big_9 PF17963.1 KFR01564.1 - 7.1e-14 52.3 6.8 2.1 9.1 0.0 10.4 11 1 0 11 11 11 5 Bacterial Ig domain Lectin_C PF00059.21 KFR01564.1 - 4.7e-12 46.6 2.3 1.4e-11 45.1 2.3 1.9 1 0 0 1 1 1 1 Lectin C-type domain Calx-beta PF03160.14 KFR01564.1 - 6.6e-10 39.1 0.1 2.1e-09 37.4 0.1 1.9 1 0 0 1 1 1 1 Calx-beta domain DAN PF03045.15 KFR01565.1 - 3.2e-28 98.0 9.4 5.8e-28 97.2 9.4 1.4 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.22 KFR01565.1 - 0.0003 21.0 7.2 0.00046 20.5 7.2 1.2 1 0 0 1 1 1 1 Cystine-knot domain Sclerostin PF05463.11 KFR01565.1 - 0.0028 17.4 2.9 0.0083 15.8 2.9 1.7 1 1 0 1 1 1 1 Sclerostin (SOST) VASP_tetra PF08776.11 KFR01565.1 - 0.0094 15.5 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 VASP tetramerisation domain DUF1661 PF07877.11 KFR01565.1 - 0.12 12.0 1.2 0.27 11.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1661) DHHC PF01529.20 KFR01566.1 - 4.4e-33 114.2 11.1 4.4e-33 114.2 11.1 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.6 KFR01566.1 - 0.22 11.5 1.1 0.38 10.7 1.1 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily Joubert PF15392.6 KFR01580.1 - 4.1e-28 99.1 0.3 4.4e-28 99.0 0.3 1.0 1 0 0 1 1 1 1 Joubert syndrome-associated DUF4472 PF14739.6 KFR01581.1 - 0.11 13.2 0.8 0.19 12.5 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) DUF3562 PF12085.8 KFR01583.1 - 0.11 12.1 0.1 1.4 8.5 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3562) DCP2 PF05026.13 KFR01585.1 - 3.3e-23 81.8 0.2 6.1e-22 77.8 0.2 2.3 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.28 KFR01585.1 - 6e-16 58.7 0.0 1.3e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain MCC-bdg_PDZ PF10506.9 KFR01586.1 - 2.1e-43 146.2 21.4 5.8e-28 96.7 7.3 7.4 6 2 3 9 9 9 2 PDZ domain of MCC-2 bdg protein for Usher syndrome Mod_r PF07200.13 KFR01586.1 - 0.00029 21.0 0.6 0.00029 21.0 0.6 6.5 5 1 0 5 5 5 1 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.11 KFR01586.1 - 0.00036 19.5 3.3 0.00036 19.5 3.3 5.7 4 1 1 5 5 5 2 Spc7 kinetochore protein FAM76 PF16046.5 KFR01586.1 - 0.0023 17.3 3.8 0.0023 17.3 3.8 5.0 2 2 3 5 5 5 1 FAM76 protein APG6_N PF17675.1 KFR01586.1 - 0.014 15.9 4.5 0.014 15.9 4.5 7.6 3 2 4 7 7 7 0 Apg6 coiled-coil region GAS PF13851.6 KFR01586.1 - 0.017 14.5 69.8 0.046 13.1 0.9 6.5 7 0 0 7 7 7 0 Growth-arrest specific micro-tubule binding SHE3 PF17078.5 KFR01586.1 - 0.017 14.8 1.7 0.017 14.8 1.7 6.3 5 2 0 6 6 6 0 SWI5-dependent HO expression protein 3 ERM PF00769.19 KFR01586.1 - 3 7.6 87.0 0.017 14.9 11.4 4.9 3 2 1 4 4 4 0 Ezrin/radixin/moesin family Homeobox_KN PF05920.11 KFR01614.1 - 1.1e-17 63.6 0.3 1.7e-17 63.0 0.3 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFR01614.1 - 1.1e-08 34.8 1.9 1.4e-08 34.5 1.9 1.1 1 0 0 1 1 1 1 Homeodomain MRP-S32 PF10210.9 KFR01614.1 - 0.021 15.4 2.1 0.025 15.1 2.1 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 Homez PF11569.8 KFR01614.1 - 0.057 12.9 0.0 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Peptidase_M10 PF00413.24 KFR01615.1 - 8.6e-69 230.4 0.0 2.8e-68 228.7 0.0 1.9 1 1 0 1 1 1 1 Matrixin fn2 PF00040.19 KFR01615.1 - 1.7e-50 169.0 42.2 1.2e-17 63.9 4.4 4.1 4 0 0 4 4 4 3 Fibronectin type II domain Hemopexin PF00045.19 KFR01615.1 - 4.8e-42 141.7 9.5 7.2e-13 48.3 0.6 4.6 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 KFR01615.1 - 3.1e-08 33.7 0.0 7.7e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.24 KFR01615.1 - 0.014 15.0 0.0 4.1 7.0 0.0 2.5 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 KFR01615.1 - 0.028 14.9 0.0 0.055 14.0 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFR01615.1 - 0.054 13.7 0.0 0.095 12.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KFR01615.1 - 0.087 12.5 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 KFR01615.1 - 0.11 11.4 0.1 0.19 10.7 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 EF-hand_1 PF00036.32 KFR01616.1 - 8.1e-19 65.7 11.7 9.9e-06 24.8 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFR01616.1 - 3e-17 61.0 6.9 5e-05 22.9 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 KFR01616.1 - 1e-16 61.1 2.9 5.2e-11 42.8 0.8 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 KFR01616.1 - 1.1e-15 57.1 11.9 6.4e-10 38.7 0.8 4.3 2 2 1 3 3 3 3 EF-hand domain pair Acyltransferase PF01553.21 KFR01616.1 - 2.2e-14 53.2 0.0 3.7e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase EF-hand_5 PF13202.6 KFR01616.1 - 4.5e-12 44.9 10.2 0.00074 18.9 0.1 4.0 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 KFR01616.1 - 0.0012 18.7 3.4 0.7 9.9 0.0 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFR01616.1 - 0.027 14.8 0.3 0.14 12.5 0.2 2.0 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Lipl32 PF12103.8 KFR01616.1 - 0.057 13.1 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 Surface lipoprotein of Spirochaetales order SNF PF00209.18 KFR01618.1 - 1.7e-238 792.5 33.6 2e-238 792.3 33.6 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family AA_permease PF00324.21 KFR01619.1 - 5.8e-63 213.1 34.6 4.7e-39 134.3 8.2 2.1 2 0 0 2 2 2 2 Amino acid permease SLC12 PF03522.15 KFR01619.1 - 4.6e-51 174.2 4.4 9.7e-33 113.8 2.1 2.9 1 1 1 2 2 2 2 Solute carrier family 12 Peptidase_M19 PF01244.21 KFR01620.1 - 6e-102 341.1 0.1 6.8e-102 340.9 0.1 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DsrC PF04358.13 KFR01620.1 - 0.02 15.4 0.2 4.8 7.8 0.0 2.8 2 1 1 3 3 3 0 DsrC like protein ProRS-C_2 PF09181.10 KFR01620.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal 7tm_1 PF00001.21 KFR01621.1 - 1.7e-55 188.2 13.6 1.9e-55 188.0 13.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFR01621.1 - 7.7e-08 32.0 15.6 9.6e-07 28.4 15.6 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 KFR01621.1 - 1.6e-07 31.0 13.8 2.1e-07 30.6 13.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFR01621.1 - 3.3e-07 30.3 10.3 4.7e-07 29.8 10.3 1.3 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFR01621.1 - 9.4e-06 25.4 14.2 2.2e-05 24.2 14.2 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srd PF10317.9 KFR01621.1 - 0.028 13.6 17.6 0.11 11.7 17.6 1.9 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd Abhydrolase_9_N PF15420.6 KFR01621.1 - 0.38 10.7 9.6 0.43 10.6 4.3 2.1 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus RHD_dimer PF16179.5 KFR01622.1 - 3.2e-25 88.1 0.2 6.2e-25 87.2 0.2 1.5 1 0 0 1 1 1 1 Rel homology dimerisation domain RHD_DNA_bind PF00554.22 KFR01622.1 - 3.5e-24 85.6 0.7 5.2e-22 78.6 0.2 3.3 3 1 0 3 3 3 1 Rel homology DNA-binding domain TIG PF01833.24 KFR01622.1 - 8.4e-06 25.8 0.1 5.4e-05 23.2 0.1 2.6 1 1 0 1 1 1 1 IPT/TIG domain 7tm_1 PF00001.21 KFR01623.1 - 5.7e-46 157.0 24.0 9.9e-46 156.2 24.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR01623.1 - 1.2e-08 34.6 27.0 1.9e-08 34.0 26.7 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFR01623.1 - 0.00036 20.2 24.9 0.00036 20.2 24.9 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF962 PF06127.11 KFR01623.1 - 0.84 9.8 3.8 16 5.7 3.8 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF962) LCAT PF02450.15 KFR01624.1 - 2.9e-88 296.7 1.4 3.5e-86 289.8 1.4 2.1 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF915 PF06028.11 KFR01624.1 - 1.4e-05 24.6 0.4 0.031 13.6 0.1 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.7 KFR01624.1 - 0.00064 20.4 0.0 0.00081 20.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFR01624.1 - 0.018 14.3 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 KFR01624.1 - 0.067 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.12 KFR01624.1 - 0.088 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Exo_endo_phos PF03372.23 KFR01625.1 - 1.2e-05 25.0 0.0 0.00013 21.6 0.0 2.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CBM_6 PF03422.15 KFR01625.1 - 0.03 14.6 0.1 0.079 13.3 0.1 1.7 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) SCPU PF05229.15 KFR01625.1 - 0.13 12.7 0.5 8.3 6.8 0.0 2.6 2 0 0 2 2 2 0 Spore Coat Protein U domain PrmA PF06325.13 KFR01626.1 - 1.8e-06 27.6 0.2 4.5e-06 26.3 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KFR01626.1 - 0.00038 20.4 0.0 0.00093 19.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFR01626.1 - 0.001 19.7 0.0 0.0027 18.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KFR01626.1 - 0.011 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_4 PF02390.17 KFR01626.1 - 0.028 13.9 0.1 0.065 12.7 0.1 1.6 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_23 PF13489.6 KFR01626.1 - 0.037 13.9 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KFR01626.1 - 0.064 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Iwr1 PF08574.10 KFR01628.1 - 2.1e-07 31.9 18.3 2.1e-07 31.9 18.3 3.0 3 2 1 4 4 4 1 Transcription factor Iwr1 AA_permease_2 PF13520.6 KFR01629.1 - 1.1e-62 212.2 41.8 1.4e-62 212.0 41.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFR01629.1 - 8e-25 87.4 34.7 8e-25 87.4 34.7 1.4 1 1 0 1 1 1 1 Amino acid permease Pkinase_Tyr PF07714.17 KFR01630.1 - 2.7e-26 92.4 0.0 3.2e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR01630.1 - 3.6e-26 92.1 0.0 4.3e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KFR01630.1 - 0.056 13.3 0.3 0.13 12.2 0.1 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pyr_redox_3 PF13738.6 KFR01631.1 - 1.3e-12 47.6 0.0 8.1e-09 35.2 0.0 2.7 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFR01631.1 - 2e-09 37.1 0.0 7.3e-08 32.0 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.6 KFR01632.1 - 4.6e-10 39.8 8.8 5.3e-07 30.0 3.6 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFR01632.1 - 9.9e-10 37.3 5.6 1e-05 24.7 0.9 2.8 1 1 2 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFR01632.1 - 1.1e-08 34.3 5.3 0.00012 21.7 0.9 2.7 1 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFR01632.1 - 3.2e-07 29.5 4.5 4.8e-06 25.8 1.4 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KFR01632.1 - 8.6e-07 28.7 3.9 0.0081 16.0 0.2 2.5 1 1 1 2 2 2 2 EF-hand domain pair ABM PF03992.16 KFR01632.1 - 7.4e-05 22.8 0.1 0.00024 21.1 0.0 1.9 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase SPARC_Ca_bdg PF10591.9 KFR01632.1 - 0.015 15.6 0.1 0.034 14.5 0.1 1.5 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFR01632.1 - 0.016 15.2 0.3 0.037 14.0 0.3 1.6 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand HAUS-augmin3 PF14932.6 KFR01632.1 - 0.067 12.8 0.5 0.12 12.0 0.5 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 EF-hand_10 PF14788.6 KFR01632.1 - 0.068 13.0 3.3 0.28 11.1 0.3 2.5 1 1 0 2 2 2 0 EF hand SMC_Nse1 PF07574.13 KFR01632.1 - 0.077 12.9 0.1 0.2 11.5 0.0 1.5 1 1 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex Aa_trans PF01490.18 KFR01633.1 - 6.6e-45 153.5 8.5 8.3e-45 153.2 8.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3648 PF12364.8 KFR01633.1 - 0.1 12.8 1.3 4.6 7.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3648) Peptidase_S8 PF00082.22 KFR01634.1 - 8.2e-40 136.9 0.1 1.3e-39 136.2 0.1 1.3 1 0 0 1 1 1 1 Subtilase family ABC_transp_aux PF09822.9 KFR01634.1 - 0.057 12.9 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 ABC-type uncharacterized transport system adh_short PF00106.25 KFR01635.1 - 1.8e-42 145.0 0.1 2.3e-42 144.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFR01635.1 - 5e-27 95.0 0.0 7e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFR01635.1 - 6e-07 29.5 0.0 1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFR01635.1 - 0.00021 20.5 0.4 0.0011 18.2 0.4 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KFR01635.1 - 0.00056 20.2 0.0 0.0018 18.5 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KFR01635.1 - 0.0019 17.7 0.5 0.031 13.7 0.5 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFR01635.1 - 0.015 15.2 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding ApbA PF02558.16 KFR01635.1 - 0.064 12.9 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Adenylsucc_synt PF00709.21 KFR01635.1 - 0.16 10.9 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Adenylosuccinate synthetase LRR_9 PF14580.6 KFR01636.1 - 2.5e-16 59.7 7.6 1e-13 51.2 6.0 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 KFR01636.1 - 1.1e-14 54.3 24.5 5.7e-05 23.4 1.2 4.4 2 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFR01636.1 - 8.3e-11 41.5 32.7 3.9e-07 29.7 1.6 3.9 2 1 3 5 5 5 4 Leucine rich repeat LRR_6 PF13516.6 KFR01636.1 - 0.0089 16.0 16.4 0.27 11.4 0.1 5.7 6 0 0 6 6 6 2 Leucine Rich repeat Arm_3 PF16186.5 KFR01636.1 - 0.66 9.6 7.5 3.2 7.4 0.1 3.9 4 1 1 5 5 5 0 Atypical Arm repeat LRR_1 PF00560.33 KFR01636.1 - 1.8 9.4 14.9 61 4.8 0.1 5.7 4 1 0 4 4 4 0 Leucine Rich Repeat HSF_DNA-bind PF00447.17 KFR01637.1 - 1.1e-31 109.3 0.5 1.1e-31 109.3 0.5 1.7 2 0 0 2 2 2 1 HSF-type DNA-binding Vert_HS_TF PF06546.11 KFR01637.1 - 3.4e-21 76.1 0.2 3.4e-21 76.1 0.2 1.8 2 0 0 2 2 2 1 Vertebrate heat shock transcription factor YscO PF07321.12 KFR01637.1 - 0.0037 17.2 5.1 0.0057 16.6 5.1 1.2 1 0 0 1 1 1 1 Type III secretion protein YscO MobL PF18555.1 KFR01637.1 - 0.0079 15.5 0.7 0.011 15.0 0.7 1.1 1 0 0 1 1 1 1 MobL relaxases Ets PF00178.22 KFR01637.1 - 0.12 12.9 1.1 0.76 10.3 0.0 2.6 3 0 0 3 3 3 0 Ets-domain Glyco_transf_41 PF13844.6 KFR01637.1 - 0.22 9.9 0.9 0.29 9.5 0.9 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 41 ZapB PF06005.12 KFR01637.1 - 0.51 10.8 9.5 0.6 10.6 8.5 1.6 1 1 0 1 1 1 0 Cell division protein ZapB TRADD_N PF09034.10 KFR01638.1 - 1.3e-47 160.5 4.3 2.1e-47 159.8 4.3 1.3 1 0 0 1 1 1 1 TRADD, N-terminal domain Death PF00531.22 KFR01638.1 - 3.3e-09 36.8 0.6 1.3e-08 34.8 0.3 2.0 2 0 0 2 2 2 1 Death domain Securin PF04856.13 KFR01638.1 - 0.048 13.6 0.1 0.065 13.2 0.1 1.4 1 0 0 1 1 1 0 Securin sister-chromatid separation inhibitor MarR PF01047.22 KFR01638.1 - 0.12 12.3 0.1 0.83 9.6 0.0 2.3 2 0 0 2 2 2 0 MarR family UPF0183 PF03676.14 KFR01639.1 - 3.5e-163 543.5 0.3 3.9e-163 543.3 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) CBF_beta PF02312.17 KFR01640.1 - 2e-48 164.2 0.1 2.2e-48 164.1 0.1 1.0 1 0 0 1 1 1 1 Core binding factor beta subunit G-alpha PF00503.20 KFR01641.1 - 2.1e-107 359.4 3.0 2.4e-107 359.2 3.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFR01641.1 - 4.2e-13 49.1 0.1 9.7e-13 47.9 0.1 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFR01641.1 - 0.00055 19.4 0.1 0.0011 18.4 0.1 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region HMG_CoA_synt_C PF08540.10 KFR01641.1 - 0.033 13.8 0.4 0.52 9.9 0.0 2.4 2 1 1 3 3 3 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal G2BR PF18442.1 KFR01642.1 - 1e-17 63.4 7.9 3.4e-17 61.8 7.9 2.0 1 0 0 1 1 1 1 E3 gp78 Ube2g2-binding region (G2BR) zf-RING_2 PF13639.6 KFR01642.1 - 3e-12 46.7 7.1 3e-12 46.7 7.1 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFR01642.1 - 3.1e-10 39.7 6.3 9.2e-10 38.2 6.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CUE PF02845.16 KFR01642.1 - 4e-10 39.2 0.1 8.3e-10 38.2 0.1 1.6 1 0 0 1 1 1 1 CUE domain zf-C3HC4 PF00097.25 KFR01642.1 - 4.5e-08 32.8 5.2 8.8e-08 31.9 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFR01642.1 - 9.8e-08 31.7 3.2 2.5e-07 30.5 3.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFR01642.1 - 1.8e-07 31.1 2.4 4.1e-07 29.9 2.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 KFR01642.1 - 6.2e-07 29.0 1.5 6.2e-07 29.0 1.5 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 KFR01642.1 - 6.3e-07 29.6 9.6 6.5e-06 26.4 8.7 2.8 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFR01642.1 - 1.6e-05 24.8 3.6 3.3e-05 23.8 3.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFR01642.1 - 1.7e-05 24.6 5.4 3.7e-05 23.5 5.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFR01642.1 - 2.7e-05 24.1 0.6 8.8e-05 22.5 0.6 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFR01642.1 - 2.8e-05 23.7 4.4 7.3e-05 22.3 4.4 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KFR01642.1 - 0.0027 17.8 4.6 0.0053 16.9 4.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING RINGv PF12906.7 KFR01642.1 - 0.27 11.4 7.6 0.6 10.3 7.6 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KFR01642.1 - 0.46 10.7 5.6 1.4 9.1 5.6 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain TarH PF02203.15 KFR01642.1 - 2.3 8.1 6.3 0.55 10.1 2.2 2.0 2 0 0 2 2 2 0 Tar ligand binding domain homologue NUDIX_2 PF13869.6 KFR01643.1 - 7.6e-78 260.4 0.0 8.5e-78 260.3 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase BBS2_C PF14782.6 KFR01644.1 - 3.1e-196 652.3 0.2 4.5e-195 648.5 0.2 2.0 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 KFR01644.1 - 7.5e-46 154.6 0.0 1.2e-43 147.6 0.0 2.8 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.6 KFR01644.1 - 2.9e-27 94.6 0.0 1.1e-26 92.7 0.1 2.1 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, N-terminal FG-GAP PF01839.23 KFR01644.1 - 2.5e-06 27.5 0.2 0.0017 18.4 0.1 2.6 2 0 0 2 2 2 2 FG-GAP repeat VCBS PF13517.6 KFR01644.1 - 1.9e-05 25.2 1.9 0.022 15.3 0.4 3.4 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Itfg2 PF15907.5 KFR01644.1 - 0.00023 20.3 0.4 0.23 10.5 0.0 3.2 2 1 1 3 3 3 2 Integrin-alpha FG-GAP repeat-containing protein 2 Metallothio PF00131.20 KFR01645.1 - 2.6e-21 75.5 63.7 2.9e-21 75.4 63.7 1.0 1 0 0 1 1 1 1 Metallothionein Nic96 PF04097.14 KFR01646.1 - 3.2e-195 650.2 0.2 5e-195 649.6 0.2 1.3 1 0 0 1 1 1 1 Nup93/Nic96 Nup84_Nup100 PF04121.13 KFR01646.1 - 0.00042 18.6 0.3 0.00083 17.6 0.3 1.4 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 AA_permease PF00324.21 KFR01647.1 - 2.4e-133 445.2 36.8 3.2e-133 444.8 36.8 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KFR01647.1 - 2.5e-116 389.3 0.1 9.1e-52 176.5 0.0 3.0 2 1 1 3 3 3 3 Solute carrier family 12 AA_permease_N PF08403.10 KFR01647.1 - 1.2e-19 69.5 0.0 4e-19 67.9 0.0 1.8 2 0 0 2 2 2 1 Amino acid permease N-terminal Tmemb_170 PF10190.9 KFR01648.1 - 2.5e-38 130.7 8.8 2.8e-38 130.5 8.8 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 Chromate_transp PF02417.15 KFR01648.1 - 0.094 12.9 8.2 0.1 12.7 8.2 1.1 1 0 0 1 1 1 0 Chromate transporter DUF4235 PF14019.6 KFR01648.1 - 0.16 12.0 3.2 0.83 9.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) DUF5489 PF17592.2 KFR01648.1 - 0.22 12.0 4.8 0.33 11.5 4.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5489) BCNT PF07572.12 KFR01649.1 - 4.6e-30 103.5 0.3 4.6e-30 103.5 0.3 3.1 3 1 1 4 4 4 1 Bucentaur or craniofacial development CAS_C PF12026.8 KFR01650.1 - 4e-82 275.3 1.1 6.2e-82 274.7 1.1 1.3 1 0 0 1 1 1 1 Crk-Associated Substrate C-terminal domain Serine_rich PF08824.10 KFR01650.1 - 7.5e-58 195.0 0.8 1.6e-57 194.0 0.0 1.9 3 0 0 3 3 3 1 Serine rich protein interaction domain SH3_1 PF00018.28 KFR01650.1 - 4.3e-14 51.8 0.0 9e-14 50.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFR01650.1 - 2.7e-13 49.6 0.0 8.8e-13 47.9 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFR01650.1 - 1.3e-10 40.8 0.0 2.8e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain FAD-oxidase_C PF02913.19 KFR01651.1 - 5e-58 196.7 0.1 1.2e-57 195.4 0.1 1.5 1 1 0 1 1 1 1 FAD linked oxidases, C-terminal domain TetR_C_33 PF13305.6 KFR01651.1 - 0.039 14.7 0.7 0.29 11.9 0.0 2.3 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain BBE PF08031.12 KFR01651.1 - 0.24 11.6 0.0 0.4 10.8 0.0 1.3 1 0 0 1 1 1 0 Berberine and berberine like Trypsin PF00089.26 KFR01652.1 - 0.014 15.2 0.1 0.016 15.1 0.1 1.1 1 0 0 1 1 1 0 Trypsin Trypsin PF00089.26 KFR01653.1 - 5.5e-49 167.0 0.0 6e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFR01653.1 - 0.00018 22.4 0.0 0.00022 22.1 0.0 1.1 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFR01653.1 - 0.025 15.0 0.0 0.04 14.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) DUF316 PF03761.15 KFR01653.1 - 0.062 12.9 0.0 0.13 11.8 0.0 1.5 2 0 0 2 2 2 0 Chymotrypsin family Peptidase-S1 FAD_binding_4 PF01565.23 KFR01654.1 - 1.5e-18 66.9 0.4 1.9e-18 66.5 0.4 1.1 1 0 0 1 1 1 1 FAD binding domain zf-RING_2 PF13639.6 KFR01655.1 - 5e-10 39.6 11.0 1.5e-09 38.0 4.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KFR01655.1 - 5.7e-06 26.0 4.4 5.7e-06 26.0 4.4 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFR01655.1 - 4.3e-05 23.3 3.6 4.3e-05 23.3 3.6 2.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KFR01655.1 - 0.00035 20.1 3.2 0.00035 20.1 3.2 1.8 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 KFR01655.1 - 0.0013 18.7 4.6 0.0013 18.7 4.6 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFR01655.1 - 0.0023 17.8 7.8 0.041 13.7 2.4 2.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFR01655.1 - 0.0025 17.7 6.5 0.1 12.6 2.7 2.2 2 0 0 2 2 2 2 zinc-RING finger domain zf-rbx1 PF12678.7 KFR01655.1 - 0.0035 17.6 4.7 0.0035 17.6 4.7 2.7 1 1 1 2 2 2 1 RING-H2 zinc finger domain FANCL_C PF11793.8 KFR01655.1 - 0.0067 16.6 7.6 0.066 13.4 3.5 2.5 2 1 0 2 2 2 1 FANCL C-terminal domain zf-RING-like PF08746.11 KFR01655.1 - 0.0068 16.7 2.0 0.0068 16.7 2.0 2.0 2 0 0 2 2 2 1 RING-like domain RNF220 PF15926.5 KFR01655.1 - 0.0096 15.6 0.2 0.012 15.3 0.2 1.2 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 zf-C3HC4 PF00097.25 KFR01655.1 - 0.011 15.6 4.0 0.011 15.6 4.0 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 KFR01655.1 - 0.026 14.5 7.8 0.45 10.5 2.9 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.7 KFR01655.1 - 0.027 14.6 2.3 0.027 14.6 2.3 2.4 2 1 0 2 2 2 0 RING-variant domain Prok-RING_4 PF14447.6 KFR01655.1 - 0.04 13.8 8.1 3.1 7.8 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf_UBZ PF18439.1 KFR01655.1 - 0.045 13.3 0.2 0.11 12.2 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger PRP21_like_P PF12230.8 KFR01655.1 - 0.058 13.3 0.0 0.067 13.1 0.0 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-RING_4 PF14570.6 KFR01655.1 - 1.8 8.5 10.5 6 6.8 4.3 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Sulfotransfer_1 PF00685.27 KFR01657.1 - 9.5e-13 48.2 0.0 1.1e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFR01657.1 - 2.6e-05 24.7 0.0 7.3e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Sulfotransferase family GDYXXLXY PF14345.6 KFR01657.1 - 0.14 12.0 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 GDYXXLXY protein Surp PF01805.20 KFR01658.1 - 4.8e-19 68.1 0.2 1.3e-18 66.7 0.2 1.8 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 KFR01658.1 - 2.5e-15 56.0 0.0 5.6e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) cwf21 PF08312.12 KFR01658.1 - 6.6e-10 39.0 2.7 6.6e-10 39.0 2.7 3.4 4 0 0 4 4 4 1 cwf21 domain CTK3 PF12243.8 KFR01658.1 - 3.6e-05 23.7 0.4 9.9e-05 22.3 0.1 1.8 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 CTD_bind PF04818.13 KFR01658.1 - 0.00088 20.0 0.6 0.0041 17.9 0.2 2.5 2 0 0 2 2 2 1 RNA polymerase II-binding domain. SET_assoc PF11767.8 KFR01658.1 - 0.014 15.0 0.1 0.034 13.8 0.1 1.6 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated HlyIII PF03006.20 KFR01659.1 - 2.3e-23 83.1 7.7 3.4e-23 82.6 7.7 1.2 1 0 0 1 1 1 1 Haemolysin-III related CUB PF00431.20 KFR01660.1 - 7.8e-61 203.2 0.0 3.4e-30 104.6 0.0 2.2 2 0 0 2 2 2 2 CUB domain NTR PF01759.21 KFR01660.1 - 1.5e-15 56.9 0.6 3.9e-15 55.6 0.0 1.9 2 0 0 2 2 2 1 UNC-6/NTR/C345C module CUB_2 PF02408.20 KFR01660.1 - 4.6e-08 32.9 0.2 0.0019 18.0 0.0 2.6 2 0 0 2 2 2 2 CUB-like domain TIMP PF00965.17 KFR01660.1 - 0.0025 17.6 0.1 0.006 16.4 0.1 1.6 1 1 0 1 1 1 1 Tissue inhibitor of metalloproteinase TRP_2 PF08344.11 KFR01661.1 - 2.2e-25 88.6 2.0 5.3e-25 87.4 2.0 1.7 1 0 0 1 1 1 1 Transient receptor ion channel II Ion_trans PF00520.31 KFR01661.1 - 2.1e-16 59.9 14.0 4e-16 59.0 14.0 1.4 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 KFR01661.1 - 2.9e-05 24.6 3.5 0.001 19.6 0.2 3.1 3 1 1 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFR01661.1 - 0.00011 22.6 0.1 1 10.1 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeats (many copies) DUF2407_C PF13373.6 KFR01661.1 - 0.045 13.9 0.1 0.26 11.4 0.0 2.4 3 0 0 3 3 3 0 DUF2407 C-terminal domain TALPID3 PF15324.6 KFR01661.1 - 0.27 8.9 3.0 0.11 10.2 0.4 1.5 2 0 0 2 2 2 0 Hedgehog signalling target CH PF00307.31 KFR01662.1 - 1.9e-90 298.3 2.1 3.9e-25 88.2 0.1 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_1 PF00036.32 KFR01662.1 - 6.6e-09 34.7 1.1 3.1e-05 23.2 0.1 3.0 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFR01662.1 - 3.1e-07 30.7 0.0 1.1e-06 28.9 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair CAMSAP_CH PF11971.8 KFR01662.1 - 7.5e-07 28.9 0.1 0.00046 20.0 0.0 3.4 4 0 0 4 4 4 1 CAMSAP CH domain EF-hand_6 PF13405.6 KFR01662.1 - 0.00012 21.7 0.2 0.22 11.5 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFR01662.1 - 0.0033 16.8 2.8 0.029 13.9 0.1 3.1 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 KFR01662.1 - 0.0036 17.1 0.2 0.32 10.9 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain pair PI3_PI4_kinase PF00454.27 KFR01663.1 - 8e-59 199.5 0.1 1.6e-58 198.5 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KFR01663.1 - 1.7e-45 155.8 4.6 1.7e-45 155.8 4.6 2.5 2 0 0 2 2 2 1 FAT domain UME PF08064.13 KFR01663.1 - 1.8e-19 69.6 5.2 2.5e-19 69.1 0.1 3.7 3 0 0 3 3 3 1 UME (NUC010) domain FATC PF02260.20 KFR01663.1 - 1.9e-12 46.8 0.0 4.8e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 KFR01663.1 - 1.5e-07 31.1 2.3 0.93 9.9 0.0 7.6 8 0 0 8 8 8 1 HEAT repeat Mad3_BUB1_I PF08311.12 KFR01663.1 - 0.001 19.0 1.2 0.014 15.4 0.1 3.5 3 0 0 3 3 3 1 Mad3/BUB1 homology region 1 HEAT_EZ PF13513.6 KFR01663.1 - 0.027 15.0 1.3 19 5.9 0.0 5.1 6 0 0 6 6 6 0 HEAT-like repeat TPR_15 PF13429.6 KFR01663.1 - 0.058 12.6 1.0 0.76 8.9 0.0 3.0 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFR01663.1 - 0.12 13.3 0.3 1e+02 4.2 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat SgrT PF15894.5 KFR01663.1 - 0.18 11.8 2.3 0.38 10.8 0.1 2.5 2 0 0 2 2 2 0 Inhibitor of glucose uptake transporter SgrT DUF3385 PF11865.8 KFR01663.1 - 0.19 11.6 7.6 22 4.9 0.1 5.7 6 0 0 6 6 6 0 Domain of unknown function (DUF3385) TPR_2 PF07719.17 KFR01663.1 - 1.9 8.8 4.3 26 5.3 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat XRN_M PF17846.1 KFR01664.1 - 2.3e-97 326.7 6.9 2.3e-97 326.7 6.9 2.1 2 0 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 KFR01664.1 - 1.7e-85 286.3 0.0 1.7e-85 286.3 0.0 2.2 3 0 0 3 3 3 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 KFR01664.1 - 1.5e-32 112.9 1.9 4.4e-32 111.4 1.9 1.7 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 KFR01664.1 - 5.4e-21 74.5 0.0 1.2e-20 73.3 0.0 1.7 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN1_D2_D3 PF18334.1 KFR01664.1 - 6e-08 32.8 0.1 4.7e-07 29.9 0.0 2.6 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain Dicer_dimer PF03368.14 KFR01664.1 - 0.055 13.6 0.0 0.29 11.3 0.0 2.3 1 0 0 1 1 1 0 Dicer dimerisation domain FGGY_N PF00370.21 KFR01665.1 - 4.4e-37 128.0 0.0 1.4e-35 123.0 0.0 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KFR01665.1 - 2e-31 109.3 0.0 4.6e-31 108.1 0.0 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DP PF08781.10 KFR01666.1 - 4.1e-60 201.7 3.9 8.1e-60 200.7 3.9 1.5 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.20 KFR01666.1 - 1.3e-26 92.4 0.2 3e-26 91.3 0.2 1.7 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Na_K-ATPase PF00287.18 KFR01667.1 - 2.6e-88 295.9 0.1 2.9e-88 295.7 0.1 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain Pkinase PF00069.25 KFR01668.1 - 1.4e-60 204.9 0.2 2e-60 204.4 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR01668.1 - 7.3e-35 120.5 0.5 1.8e-34 119.2 0.1 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase RGS PF00615.19 KFR01668.1 - 5.5e-14 52.4 2.0 5.5e-14 52.4 2.0 2.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain Pkinase_fungal PF17667.1 KFR01668.1 - 2.8e-05 23.1 0.0 4.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFR01668.1 - 7.1e-05 22.3 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Nif11 PF07862.11 KFR01668.1 - 0.15 12.4 1.3 4.5 7.7 0.1 2.7 2 0 0 2 2 2 0 Nif11 domain zf-rbx1 PF12678.7 KFR01669.1 - 3.8e-16 59.1 16.5 4.5e-16 58.9 16.5 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFR01669.1 - 1.6e-08 34.5 10.9 1.7e-08 34.4 10.9 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KFR01669.1 - 3e-08 33.9 13.1 4.2e-08 33.4 13.1 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFR01669.1 - 6.4e-05 22.7 12.1 0.00011 21.9 12.1 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFR01669.1 - 0.0011 18.8 10.2 0.0017 18.1 10.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFR01669.1 - 0.0017 18.2 13.6 0.0034 17.2 13.6 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 KFR01669.1 - 0.0076 16.2 9.6 0.05 13.5 5.2 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_5 PF14634.6 KFR01669.1 - 0.046 13.7 13.9 0.04 13.9 12.9 1.4 1 1 0 1 1 1 0 zinc-RING finger domain PHD PF00628.29 KFR01669.1 - 0.75 9.7 14.5 1.7 8.6 14.5 1.6 1 1 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.6 KFR01669.1 - 0.83 9.6 14.8 0.78 9.7 13.5 1.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KFR01669.1 - 1.6 8.6 13.2 0.59 10.0 11.0 1.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KFR01669.1 - 3 7.7 11.0 0.54 10.1 7.3 1.8 2 0 0 2 2 2 0 RING-like zinc finger zf-C3H2C3 PF17122.5 KFR01669.1 - 7 6.8 12.8 9.4 6.4 11.9 1.9 1 1 0 1 1 1 0 Zinc-finger C2 PF00168.30 KFR01670.1 - 3.2e-32 110.9 3.8 3.7e-15 56.1 0.1 3.5 2 1 0 2 2 2 2 C2 domain RasGAP PF00616.19 KFR01670.1 - 1.5e-26 93.5 0.3 1.1e-16 61.1 0.0 3.1 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase PH PF00169.29 KFR01670.1 - 2e-16 60.4 0.7 2e-16 60.4 0.7 3.1 4 0 0 4 4 4 1 PH domain BTK PF00779.19 KFR01670.1 - 1.1e-12 47.5 2.3 2.4e-12 46.4 2.3 1.6 1 0 0 1 1 1 1 BTK motif CEP76-C2 PF15627.6 KFR01670.1 - 9.5e-05 22.0 0.3 0.3 10.7 0.0 2.8 3 0 0 3 3 3 2 CEP76 C2 domain PH_8 PF15409.6 KFR01670.1 - 0.0062 16.8 0.6 0.019 15.3 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Glyco_trans_1_2 PF13524.6 KFR01670.1 - 0.023 15.1 0.0 0.053 13.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 DNA_pol3_beta_2 PF02767.16 KFR01670.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III beta subunit, central domain F-box-like PF12937.7 KFR01672.1 - 1.7e-10 40.6 0.3 3.7e-10 39.5 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFR01672.1 - 1.6e-08 34.2 2.9 3.6e-08 33.1 0.8 2.5 2 1 1 3 3 3 1 F-box domain F-box_4 PF15966.5 KFR01672.1 - 0.00064 19.6 1.5 0.0048 16.8 0.0 2.6 2 1 1 3 3 3 1 F-box Fructosamin_kin PF03881.14 KFR01672.1 - 0.14 11.4 0.2 0.19 10.9 0.2 1.2 1 0 0 1 1 1 0 Fructosamine kinase HECT PF00632.25 KFR01673.1 - 1.6e-87 293.9 0.6 5e-87 292.2 0.0 2.1 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) WWE PF02825.20 KFR01673.1 - 0.00031 21.3 0.7 0.0012 19.3 0.7 2.0 1 1 0 1 1 1 1 WWE domain HEAT_2 PF13646.6 KFR01673.1 - 0.075 13.4 0.1 0.99 9.8 0.0 3.0 3 1 1 4 4 4 0 HEAT repeats PID_2 PF14719.6 KFR01674.1 - 1.8e-18 67.0 0.4 3e-18 66.3 0.4 1.3 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.23 KFR01674.1 - 9.1e-07 29.0 0.2 1.4e-06 28.4 0.2 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Yae1_N PF09811.9 KFR01675.1 - 6e-15 54.7 53.3 0.26 11.0 1.2 5.4 1 1 1 2 2 2 1 Essential protein Yae1, N terminal Peptidase_A17 PF05380.13 KFR01676.1 - 0.21 11.6 1.1 0.38 10.7 0.1 1.8 1 1 1 2 2 2 0 Pao retrotransposon peptidase AKAP_110 PF05716.13 KFR01677.1 - 1.9e-08 33.0 0.0 3.5e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 A-kinase anchor protein 110 kDa (AKAP 110) SmAKAP PF15127.6 KFR01677.1 - 0.0011 20.1 8.1 9 7.6 0.0 6.3 5 1 0 5 5 5 1 Small membrane A-kinase anchor protein WD40 PF00400.32 KFR01678.1 - 3.7e-67 220.6 19.5 5.2e-08 33.4 0.4 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR01678.1 - 1.5e-23 82.9 1.0 0.0026 18.0 0.0 7.3 1 1 7 8 8 8 7 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFR01678.1 - 4.5e-11 42.6 0.8 0.23 10.8 0.0 5.8 2 2 3 6 6 6 5 WD40-like domain Nup160 PF11715.8 KFR01678.1 - 1.8e-06 26.9 2.7 1.1 7.8 0.0 5.8 2 1 5 7 7 7 3 Nucleoporin Nup120/160 WD40_3 PF15911.5 KFR01678.1 - 0.00024 21.0 0.0 0.44 10.6 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KFR01678.1 - 0.0018 17.3 5.7 0.1 11.5 0.3 3.8 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IL8 PF00048.20 KFR01679.1 - 9.3e-18 64.1 0.0 1.1e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Folate_carrier PF01770.18 KFR01680.1 - 6.9e-178 591.6 15.4 8.2e-178 591.3 15.4 1.0 1 0 0 1 1 1 1 Reduced folate carrier MFS_1 PF07690.16 KFR01680.1 - 3.6e-12 45.9 15.8 6.1e-12 45.1 15.8 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4231 PF14015.6 KFR01680.1 - 0.12 12.8 0.3 0.12 12.8 0.3 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) ArfGap PF01412.18 KFR01681.1 - 1.2e-10 41.4 0.0 2.5e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf dsrm PF00035.26 KFR01682.1 - 0.0016 19.1 0.0 0.0034 18.1 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Miff PF05644.11 KFR01683.1 - 4.9e-143 476.1 2.1 5.5e-143 475.9 2.1 1.0 1 0 0 1 1 1 1 Mitochondrial and peroxisomal fission factor Mff Collagen PF01391.18 KFR01684.1 - 1.4e-185 601.3 706.6 2.9e-10 39.8 28.7 27.0 6 6 18 24 24 24 24 Collagen triple helix repeat (20 copies) C4 PF01413.19 KFR01684.1 - 6.1e-80 264.9 3.9 1.2e-41 141.5 0.3 2.1 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Rhomboid PF01694.22 KFR01685.1 - 2e-18 66.8 7.6 3.3e-18 66.1 7.6 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 KFR01685.1 - 0.13 12.8 4.3 0.067 13.8 1.7 1.8 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) COPI_assoc PF08507.10 KFR01685.1 - 1.1 9.4 7.9 0.093 12.8 0.7 2.6 3 0 0 3 3 3 0 COPI associated protein UPF0139 PF03669.13 KFR01685.1 - 2.2 8.2 5.6 29 4.6 0.0 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0139) IRS PF02174.17 KFR01686.1 - 3.9e-31 106.9 0.0 6.2e-31 106.2 0.0 1.3 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.29 KFR01686.1 - 1.8e-10 41.3 0.1 3.5e-10 40.3 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFR01686.1 - 5.5e-05 23.5 0.1 0.0001 22.7 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain Peptidase_M10 PF00413.24 KFR01687.1 - 1.6e-60 203.5 0.0 2.6e-60 202.9 0.0 1.3 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 KFR01687.1 - 1.5e-55 184.9 16.4 1.4e-16 60.1 0.6 4.6 4 0 0 4 4 4 4 Hemopexin DUF3377 PF11857.8 KFR01687.1 - 4.3e-32 109.9 0.3 7.7e-32 109.0 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) PG_binding_1 PF01471.18 KFR01687.1 - 1e-09 38.4 0.1 3.9e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Astacin PF01400.24 KFR01687.1 - 9.4e-05 22.1 0.9 0.33 10.6 0.0 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Peptidase_M66 PF10462.9 KFR01687.1 - 0.036 13.0 0.1 0.059 12.3 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M54 PF07998.11 KFR01687.1 - 0.048 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M54 Metallopep PF12044.8 KFR01687.1 - 0.066 11.8 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_3 PF13582.6 KFR01687.1 - 0.1 13.1 0.1 0.21 12.1 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFR01687.1 - 0.27 11.4 0.2 0.67 10.1 0.2 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12 Pkinase_Tyr PF07714.17 KFR01688.1 - 7.4e-38 130.3 0.0 1e-37 129.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR01688.1 - 2.5e-33 115.6 0.0 4.2e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain CARD PF00619.21 KFR01688.1 - 8.7e-19 67.4 0.4 1.7e-18 66.4 0.4 1.5 1 0 0 1 1 1 1 Caspase recruitment domain Kinase-like PF14531.6 KFR01688.1 - 0.011 15.0 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like EB1_binding PF05937.11 KFR01688.1 - 0.054 14.1 4.1 2.9 8.5 1.1 2.3 2 0 0 2 2 2 0 EB-1 Binding Domain APH PF01636.23 KFR01688.1 - 0.23 11.4 0.1 0.5 10.2 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family AA_permease_2 PF13520.6 KFR01689.1 - 8.6e-63 212.6 34.4 1e-62 212.4 34.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFR01689.1 - 8.1e-26 90.6 29.9 1.1e-25 90.2 29.9 1.2 1 0 0 1 1 1 1 Amino acid permease adh_short_C2 PF13561.6 KFR01690.1 - 5.7e-48 163.5 0.3 8.1e-48 163.0 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFR01690.1 - 1.3e-34 119.4 1.5 1.8e-34 118.9 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFR01690.1 - 3.8e-07 30.2 0.2 5.3e-07 29.7 0.2 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KFR01690.1 - 0.014 15.9 0.5 0.031 14.9 0.5 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KFR01690.1 - 0.019 15.2 0.6 0.037 14.3 0.6 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 KFR01690.1 - 0.037 13.0 0.1 0.055 12.5 0.1 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFR01690.1 - 0.041 13.3 0.1 0.074 12.5 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFR01690.1 - 0.049 13.0 0.1 0.068 12.6 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase EF-hand_1 PF00036.32 KFR01691.1 - 2.3e-24 83.1 10.5 1.4e-07 30.6 1.0 5.4 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KFR01691.1 - 3.1e-24 82.8 9.9 8.9e-08 31.5 0.6 5.5 5 0 0 5 5 5 5 EF-hand domain EF-hand_7 PF13499.6 KFR01691.1 - 9.4e-22 77.3 7.4 3e-11 43.6 2.2 3.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KFR01691.1 - 2.1e-15 55.4 7.4 0.00035 19.9 0.0 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 KFR01691.1 - 1.3e-09 37.7 2.7 2.3e-06 27.3 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain pair T3SS_HrpK1 PF16937.5 KFR01691.1 - 0.00067 19.4 0.2 0.1 12.2 0.0 2.4 2 1 1 3 3 3 1 Type III secretion system translocator protein, HrpF SPARC_Ca_bdg PF10591.9 KFR01691.1 - 0.0027 18.0 3.8 1.1 9.6 0.1 3.4 1 1 2 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region LXG PF04740.12 KFR01691.1 - 0.012 15.3 3.8 1.2 8.8 0.3 3.0 3 0 0 3 3 3 0 LXG domain of WXG superfamily Caleosin PF05042.13 KFR01691.1 - 0.027 14.4 2.2 2.7 7.9 0.1 3.1 1 1 2 3 3 3 0 Caleosin related protein Styelin PF17562.2 KFR01691.1 - 0.035 14.5 0.1 0.57 10.6 0.0 2.5 2 0 0 2 2 2 0 Styelin ArgoMid PF16487.5 KFR01691.1 - 0.088 13.1 0.4 3.6 7.9 0.0 3.0 3 1 0 3 3 3 0 Mid domain of argonaute EF-hand_9 PF14658.6 KFR01691.1 - 0.13 12.6 0.3 27 5.2 0.0 3.2 3 1 0 3 3 3 0 EF-hand domain EF-hand_10 PF14788.6 KFR01691.1 - 0.16 11.9 10.3 2.6 8.0 0.4 4.3 3 1 1 4 4 4 0 EF hand Dockerin_1 PF00404.18 KFR01691.1 - 0.24 11.6 3.0 1.8 8.8 0.1 3.1 2 2 2 4 4 4 0 Dockerin type I domain SNARE_assoc PF09335.11 KFR01692.1 - 2.1e-18 67.0 6.2 2.1e-18 67.0 6.2 2.0 2 1 0 2 2 2 1 SNARE associated Golgi protein ABM PF03992.16 KFR01693.1 - 1.7e-10 40.9 0.1 3.6e-10 39.8 0.1 1.6 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase EF-hand_1 PF00036.32 KFR01693.1 - 3.6e-05 23.0 1.2 0.44 10.2 0.0 3.3 2 1 2 4 4 4 2 EF hand EF-hand_7 PF13499.6 KFR01693.1 - 5e-05 23.7 2.3 0.0077 16.7 0.5 2.9 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KFR01693.1 - 6.6e-05 22.5 0.4 0.12 12.3 0.1 3.6 2 1 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 KFR01693.1 - 0.00033 20.4 1.0 0.0048 16.7 1.0 2.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KFR01693.1 - 0.0022 17.4 0.1 1.5 8.4 0.0 2.8 1 1 1 2 2 2 2 EF hand zf-C4H2 PF10146.9 KFR01693.1 - 0.097 13.0 3.5 1.1 9.6 0.3 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein UCH_1 PF13423.6 KFR01693.1 - 0.28 10.7 6.0 0.35 10.4 6.0 1.4 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase RraB PF06877.11 KFR01693.1 - 0.35 11.6 3.6 0.21 12.3 0.9 2.0 2 0 0 2 2 1 0 Regulator of ribonuclease activity B EF-hand_10 PF14788.6 KFR01693.1 - 0.42 10.5 6.5 1.3 8.9 0.6 3.9 4 1 0 4 4 4 0 EF hand Exonuc_VII_S PF02609.16 KFR01693.1 - 0.63 10.2 8.1 0.9 9.6 0.1 3.4 4 0 0 4 4 4 0 Exonuclease VII small subunit Uso1_p115_C PF04871.13 KFR01693.1 - 1.9 8.8 8.6 3 8.2 1.4 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region ZapB PF06005.12 KFR01693.1 - 5.6 7.5 11.9 1.3 9.5 0.2 3.2 2 2 0 2 2 2 0 Cell division protein ZapB eIF_4EBP PF05456.11 KFR01694.1 - 0.014 15.3 0.0 0.014 15.3 0.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Tmemb_55A PF09788.9 KFR01695.1 - 2.7e-97 324.7 15.7 3e-97 324.5 15.7 1.0 1 0 0 1 1 1 1 Transmembrane protein 55A zf-BED PF02892.15 KFR01695.1 - 0.015 15.3 9.3 0.4 10.7 0.0 3.9 3 1 1 4 4 4 0 BED zinc finger zinc_ribbon_12 PF11331.8 KFR01695.1 - 0.084 12.7 0.6 0.084 12.7 0.6 3.8 3 1 1 4 4 4 0 Probable zinc-ribbon domain zinc_ribbon_4 PF13717.6 KFR01695.1 - 0.48 10.4 0.0 0.48 10.4 0.0 4.9 5 1 1 6 6 6 0 zinc-ribbon domain OTU PF02338.19 KFR01696.1 - 6.3e-33 114.0 0.8 1.5e-32 112.8 0.0 1.9 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KFR01696.1 - 1.3e-09 37.9 0.1 1.6e-05 24.5 0.0 2.7 1 1 1 2 2 2 2 Peptidase C65 Otubain IFP_35_N PF07334.13 KFR01696.1 - 0.046 13.8 4.9 0.12 12.5 4.9 1.6 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DDHD PF02862.17 KFR01696.1 - 0.65 10.1 2.6 0.75 9.9 2.6 1.2 1 0 0 1 1 1 0 DDHD domain NHR2 PF08788.11 KFR01697.1 - 4.7e-40 135.2 8.8 1.5e-39 133.6 8.8 1.9 1 0 0 1 1 1 1 NHR2 domain like TAFH PF07531.14 KFR01697.1 - 2.2e-34 117.4 1.4 4.2e-34 116.5 1.4 1.5 1 0 0 1 1 1 1 NHR1 homology to TAF zf-MYND PF01753.18 KFR01697.1 - 2.8e-07 30.5 18.2 2.8e-07 30.5 18.2 2.0 2 0 0 2 2 2 1 MYND finger Efg1 PF10153.9 KFR01697.1 - 0.026 14.9 2.0 0.079 13.3 2.0 1.8 1 0 0 1 1 1 0 rRNA-processing protein Efg1 DUF3731 PF12531.8 KFR01697.1 - 0.1 12.4 3.7 0.037 13.8 1.0 1.6 2 0 0 2 2 2 0 DNA-K related protein DUF4434 PF14488.6 KFR01697.1 - 0.13 12.2 0.2 0.13 12.2 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4434) MAJIN PF15077.6 KFR01697.1 - 0.3 10.8 3.5 0.62 9.8 3.5 1.5 1 0 0 1 1 1 0 Membrane-anchored junction protein vATP-synt_E PF01991.18 KFR01697.1 - 1.1 8.6 12.4 1.8 8.0 12.4 1.3 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit ARGLU PF15346.6 KFR01697.1 - 2.1 8.2 14.0 0.2 11.5 7.0 2.2 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 DivIVA PF05103.13 KFR01697.1 - 3.2 7.8 9.1 7.7 6.6 9.1 1.6 1 0 0 1 1 1 0 DivIVA protein DDE_1 PF03184.19 KFR01698.1 - 3.3e-12 46.4 0.0 4.5e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Lambda_Kil PF06301.11 KFR01698.1 - 0.067 12.8 0.7 12 5.6 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage lambda Kil protein TRIQK PF15168.6 KFR01699.1 - 2.4e-25 88.2 0.8 2.6e-25 88.1 0.8 1.0 1 0 0 1 1 1 1 Triple QxxK/R motif-containing protein family TNFR_16_TM PF18422.1 KFR01699.1 - 3.9 7.5 4.8 5.8 7.0 4.8 1.2 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain FAM92 PF06730.11 KFR01700.1 - 1.1e-102 342.2 10.8 1.3e-102 342.0 10.8 1.0 1 0 0 1 1 1 1 FAM92 protein Vps5 PF09325.10 KFR01700.1 - 0.0062 16.1 7.7 1 8.8 7.7 3.0 1 1 0 1 1 1 1 Vps5 C terminal like P4Ha_N PF08336.11 KFR01700.1 - 0.0074 16.3 1.1 0.0074 16.3 1.1 2.2 1 1 1 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region HTH_42 PF06224.12 KFR01700.1 - 0.023 14.2 0.3 0.036 13.6 0.3 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain CemA PF03040.14 KFR01700.1 - 0.13 12.2 1.3 0.21 11.5 1.3 1.4 1 0 0 1 1 1 0 CemA family SAM_Exu PF18609.1 KFR01700.1 - 0.18 12.0 3.1 1.5 8.9 0.9 2.8 2 0 0 2 2 2 0 Exuperantia SAM-like domain RRM_1 PF00076.22 KFR01701.1 - 2.5e-24 84.9 0.2 2.3e-06 27.3 0.3 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Meckelin PF09773.9 KFR01702.1 - 0 1153.5 12.8 0 1153.5 12.8 1.7 2 0 0 2 2 2 1 Meckelin (Transmembrane protein 67) NCD3G PF07562.14 KFR01702.1 - 0.14 12.2 15.4 0.021 14.8 5.2 2.7 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR PP2C PF00481.21 KFR01703.1 - 8.3e-36 123.9 0.0 7.1e-35 120.9 0.0 2.0 1 1 1 2 2 2 1 Protein phosphatase 2C Cadherin PF00028.17 KFR01704.1 - 1.6e-60 201.6 11.6 4.1e-13 49.6 0.1 7.2 7 0 0 7 7 7 6 Cadherin domain RET_CLD1 PF17756.1 KFR01704.1 - 2.3e-07 31.1 0.0 0.47 10.7 0.0 4.8 5 0 0 5 5 5 2 RET Cadherin like domain 1 Cadherin_3 PF16184.5 KFR01704.1 - 1.5e-06 28.2 5.4 0.91 9.6 0.2 5.2 5 0 0 5 5 5 3 Cadherin-like Cadherin_4 PF17803.1 KFR01704.1 - 0.0067 17.0 12.1 4.5 8.0 0.5 5.6 5 1 0 5 5 5 2 Bacterial cadherin-like domain Invasin_D3 PF09134.10 KFR01704.1 - 0.05 13.9 5.0 7 7.0 0.0 4.7 5 0 0 5 5 5 0 Invasin, domain 3 Ras PF00071.22 KFR01705.1 - 1.9e-31 108.8 0.0 5.6e-31 107.3 0.0 1.7 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KFR01705.1 - 3.5e-09 36.9 0.0 8.7e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KFR01705.1 - 3.3e-05 23.9 0.0 6.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFR01705.1 - 0.00017 21.2 0.1 0.00096 18.7 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFR01705.1 - 0.00046 20.1 0.0 0.77 9.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase pXO2-34 PF17362.2 KFR01705.1 - 0.04 13.8 0.6 16 5.4 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function Dynamin_N PF00350.23 KFR01705.1 - 0.043 13.9 2.6 0.045 13.8 0.2 2.2 3 0 0 3 3 3 0 Dynamin family ABC_tran PF00005.27 KFR01705.1 - 0.049 14.2 0.0 0.097 13.2 0.0 1.8 1 1 0 1 1 1 0 ABC transporter DUF2369 PF10179.9 KFR01705.1 - 0.094 13.1 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) AAA_22 PF13401.6 KFR01705.1 - 0.12 12.7 0.2 39 4.5 0.1 3.0 2 1 1 3 3 3 0 AAA domain Myb_DNA-bind_5 PF13873.6 KFR01706.1 - 1.1e-21 76.6 0.1 1.1e-21 76.6 0.1 2.9 3 1 0 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KFR01706.1 - 0.065 13.6 0.2 0.14 12.5 0.2 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain zf-C3HC4_2 PF13923.6 KFR01707.1 - 9.2e-10 38.2 8.1 9.2e-10 38.2 8.1 2.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 KFR01707.1 - 6.7e-08 33.1 3.8 6.7e-08 33.1 3.8 3.4 1 1 2 3 3 3 1 TRAF-type zinc finger zf-C3HC4 PF00097.25 KFR01707.1 - 1.2e-07 31.5 7.5 1.2e-07 31.5 7.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFR01707.1 - 1.5e-06 28.1 8.5 1.5e-06 28.1 8.5 2.0 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFR01707.1 - 1.8e-06 28.0 6.1 1.8e-06 28.0 6.1 2.7 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFR01707.1 - 1.8e-06 28.1 7.9 1.8e-06 28.1 7.9 3.0 2 1 0 2 2 1 1 Ring finger domain Sina PF03145.16 KFR01707.1 - 4.6e-06 26.7 10.7 1.1e-05 25.4 3.1 2.9 1 1 2 3 3 3 2 Seven in absentia protein family zf-C3HC4_3 PF13920.6 KFR01707.1 - 6.3e-06 26.0 3.4 6.3e-06 26.0 3.4 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KFR01707.1 - 0.00031 20.6 1.8 0.00031 20.6 1.8 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-TRAF_2 PF15965.5 KFR01707.1 - 0.00055 20.4 7.8 0.0037 17.7 0.5 3.6 2 1 2 4 4 4 2 TRAF-like zinc-finger Prok-RING_4 PF14447.6 KFR01707.1 - 0.0011 18.7 7.2 0.0011 18.7 7.2 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFR01707.1 - 0.0076 16.2 5.7 0.0076 16.2 5.7 2.6 2 1 0 2 2 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 KFR01707.1 - 0.01 16.0 6.9 0.032 14.4 6.9 2.0 1 1 0 1 1 1 0 zinc RING finger of MSL2 DUF1640 PF07798.11 KFR01707.1 - 0.016 15.3 8.5 0.027 14.5 8.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) zf-rbx1 PF12678.7 KFR01707.1 - 0.018 15.3 10.7 0.018 15.3 10.7 4.1 3 2 1 4 4 4 0 RING-H2 zinc finger domain GCN5L1 PF06320.13 KFR01707.1 - 0.1 12.7 5.9 0.16 12.1 5.9 1.2 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) LPP PF04728.13 KFR01707.1 - 0.11 13.0 1.3 0.3 11.5 1.3 1.8 1 0 0 1 1 1 0 Lipoprotein leucine-zipper DUF3552 PF12072.8 KFR01707.1 - 0.12 11.8 10.5 0.17 11.3 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Fzo_mitofusin PF04799.13 KFR01707.1 - 0.39 10.3 6.7 0.71 9.4 6.7 1.5 1 0 0 1 1 1 0 fzo-like conserved region DUF1664 PF07889.12 KFR01707.1 - 0.57 10.2 5.2 0.96 9.5 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF1515 PF07439.11 KFR01707.1 - 1.8 8.6 4.4 3 7.9 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) VIR_N PF15912.5 KFR01708.1 - 7.8e-98 327.2 16.2 7.8e-98 327.2 16.2 2.3 1 1 1 2 2 2 1 Virilizer, N-terminal tRNA_anti_2 PF13742.6 KFR01708.1 - 0.026 14.7 0.1 0.11 12.8 0.1 2.0 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain SDA1 PF05285.12 KFR01708.1 - 0.14 11.6 26.2 0.23 10.8 26.2 1.3 1 0 0 1 1 1 0 SDA1 CDC27 PF09507.10 KFR01708.1 - 8.4 5.7 15.4 17 4.7 15.4 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RRM_1 PF00076.22 KFR01709.1 - 3.3e-15 55.7 0.0 0.00083 19.1 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 KFR01709.1 - 0.013 16.0 0.0 0.026 15.1 0.0 1.4 1 0 0 1 1 1 0 Exonuclease PHM7_cyt PF14703.6 KFR01709.1 - 0.15 12.3 0.0 22 5.2 0.0 3.1 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter Dpy19 PF10034.9 KFR01710.1 - 1.3e-212 707.6 31.1 1.7e-212 707.2 31.1 1.1 1 0 0 1 1 1 1 Q-cell neuroblast polarisation Complex1_LYR_1 PF13232.6 KFR01710.1 - 0.082 13.5 0.1 0.25 12.0 0.1 1.8 1 0 0 1 1 1 0 Complex1_LYR-like DUF4405 PF14358.6 KFR01710.1 - 0.11 13.0 3.9 4.5 7.9 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) Cadherin PF00028.17 KFR01711.1 - 3.9e-210 681.1 21.4 4.4e-20 71.9 0.0 15.4 15 0 0 15 15 15 14 Cadherin domain Cadherin_C PF01049.17 KFR01711.1 - 6.2e-41 140.1 0.3 1.5e-40 138.8 0.3 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic region Laminin_G_2 PF02210.24 KFR01711.1 - 8.5e-34 116.9 2.1 8.4e-19 68.4 0.0 3.0 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 KFR01711.1 - 1.3e-27 96.6 0.1 2.2e-12 47.3 0.0 2.7 2 0 0 2 2 2 2 Laminin G domain EGF PF00008.27 KFR01711.1 - 2.8e-15 56.3 47.4 1.4e-06 28.4 8.0 4.6 4 0 0 4 4 4 4 EGF-like domain Cadherin_pro PF08758.11 KFR01711.1 - 1.1e-10 41.6 0.0 6.6e-05 23.0 0.0 7.0 9 0 0 9 9 8 1 Cadherin prodomain like hEGF PF12661.7 KFR01711.1 - 2.8e-10 40.4 35.6 0.0014 19.2 4.2 4.8 4 0 0 4 4 4 4 Human growth factor-like EGF Cadherin_2 PF08266.12 KFR01711.1 - 9.9e-10 38.1 0.0 0.26 11.2 0.0 7.5 8 0 0 8 8 8 2 Cadherin-like RET_CLD1 PF17756.1 KFR01711.1 - 1.1e-07 32.1 0.5 1.7 8.9 0.0 7.3 8 0 0 8 8 6 1 RET Cadherin like domain 1 Y_Y_Y PF07495.13 KFR01711.1 - 9.1e-06 25.5 3.9 0.39 10.7 0.1 4.8 4 0 0 4 4 4 2 Y_Y_Y domain EGF_2 PF07974.13 KFR01711.1 - 0.00066 20.0 59.2 0.0084 16.5 12.2 4.1 4 0 0 4 4 4 2 EGF-like domain DUF4975 PF16346.5 KFR01711.1 - 0.089 12.9 0.5 0.38 10.8 0.5 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4975) TPR_2 PF07719.17 KFR01712.1 - 0.00023 21.0 4.1 0.25 11.5 0.3 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFR01712.1 - 0.0077 15.9 0.6 0.72 9.6 0.2 2.9 2 0 0 2 2 2 1 TPR repeat TPR_7 PF13176.6 KFR01712.1 - 0.029 14.4 0.7 3 8.1 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFR01712.1 - 0.048 13.9 4.7 7.7 7.0 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFR01712.1 - 0.11 12.3 7.3 2.6 8.0 0.7 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFR01712.1 - 2.8 8.2 6.1 1.2 9.4 0.4 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Cyclin_N PF00134.23 KFR01713.1 - 1.2e-39 134.9 1.5 2.5e-39 133.9 1.5 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFR01713.1 - 1.6e-18 66.9 0.2 3.3e-18 65.9 0.2 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain DOR PF14839.6 KFR01714.1 - 2.2e-81 273.5 9.5 4.5e-81 272.5 9.5 1.5 1 1 0 1 1 1 1 DOR family Thioredoxin_7 PF13899.6 KFR01714.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like SQS_PSY PF00494.19 KFR01715.1 - 3.6e-53 180.7 0.2 4.2e-53 180.5 0.2 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase FYVE PF01363.21 KFR01716.1 - 6.6e-19 67.8 7.4 1.5e-18 66.7 7.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 KFR01716.1 - 5.5e-11 42.9 0.5 2e-10 41.1 0.1 2.1 2 1 1 3 3 3 1 PH domain FYVE_2 PF02318.16 KFR01716.1 - 0.0012 19.1 5.4 0.0022 18.2 5.4 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger PH_13 PF16652.5 KFR01716.1 - 0.0038 17.0 0.7 0.11 12.3 0.7 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_16 PF17838.1 KFR01716.1 - 0.0062 16.4 0.1 0.027 14.3 0.1 1.9 1 1 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 KFR01716.1 - 0.025 14.5 0.1 0.052 13.5 0.1 1.5 1 0 0 1 1 1 0 PH domain DUF1835 PF08874.10 KFR01716.1 - 0.053 13.7 0.1 0.13 12.5 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1835) zf-HYPF PF07503.12 KFR01716.1 - 3.9 7.3 7.8 14 5.6 7.8 2.0 1 1 0 1 1 1 0 HypF finger zf-B_box PF00643.24 KFR01716.1 - 6 7.1 9.3 5.8 7.2 6.3 2.4 2 1 0 2 2 2 0 B-box zinc finger RMP PF14996.6 KFR01717.1 - 4.8e-53 179.5 6.7 5.3e-53 179.4 6.7 1.0 1 0 0 1 1 1 1 Retinal Maintenance Herpes_UL37_2 PF07413.11 KFR01717.1 - 0.044 13.0 0.1 0.05 12.8 0.1 1.1 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 UCR_14kD PF02271.16 KFR01718.1 - 4.7e-40 135.6 1.0 5.5e-40 135.4 1.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit mTERF PF02536.14 KFR01719.1 - 2.6e-28 98.9 1.2 3.4e-28 98.5 1.2 1.1 1 0 0 1 1 1 1 mTERF PSS PF03034.15 KFR01720.1 - 2.4e-105 352.2 23.8 2.4e-105 352.2 23.8 1.8 2 0 0 2 2 2 1 Phosphatidyl serine synthase Cyt_b-c1_8 PF10890.8 KFR01720.1 - 0.096 13.1 0.1 0.33 11.4 0.1 1.9 2 0 0 2 2 2 0 Cytochrome b-c1 complex subunit 8 Peptidase_C1 PF00112.23 KFR01720.1 - 0.11 12.6 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Papain family cysteine protease Syndecan PF01034.20 KFR01722.1 - 5.1e-30 103.2 0.0 9.2e-30 102.4 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain DUF2721 PF11026.8 KFR01722.1 - 0.037 13.9 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF2207 PF09972.9 KFR01722.1 - 0.04 12.7 0.0 0.043 12.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Peptidase_M50 PF02163.22 KFR01722.1 - 0.046 13.0 0.0 0.058 12.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M50 DUF2407_C PF13373.6 KFR01722.1 - 0.11 12.7 0.0 0.17 12.0 0.0 1.3 1 1 0 1 1 1 0 DUF2407 C-terminal domain DUF4407 PF14362.6 KFR01722.1 - 0.16 11.3 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TGF_beta_GS PF08515.12 KFR01722.1 - 0.24 11.0 0.9 0.65 9.5 0.9 1.8 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Glycophorin_A PF01102.18 KFR01722.1 - 0.32 11.2 5.6 1.5 9.0 5.6 2.0 1 1 0 1 1 1 0 Glycophorin A MtrF PF09472.10 KFR01722.1 - 0.4 10.1 2.9 0.67 9.4 2.9 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Glypican PF01153.19 KFR01722.1 - 0.4 9.5 2.2 0.48 9.2 2.2 1.2 1 0 0 1 1 1 0 Glypican PA PF02225.22 KFR01723.1 - 0.00052 20.0 0.1 0.00092 19.2 0.1 1.4 1 0 0 1 1 1 1 PA domain Peptidase_M28 PF04389.17 KFR01724.1 - 1e-22 80.8 0.0 1.2e-22 80.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KFR01724.1 - 1.9e-08 34.3 0.0 2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 dbPDZ_assoc PF16610.5 KFR01724.1 - 0.21 11.8 0.0 0.48 10.7 0.0 1.5 2 0 0 2 2 2 0 Unstructured region between two PDZ domains on Dlg5 RVT_1 PF00078.27 KFR01726.1 - 0.0023 17.5 0.0 0.004 16.7 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) ig PF00047.25 KFR01726.1 - 0.074 13.2 0.0 0.088 13.0 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain LYRIC PF15686.5 KFR01727.1 - 1.1e-96 325.0 28.5 1.1e-96 325.0 28.5 2.2 1 1 1 2 2 2 1 Lysine-rich CEACAM1 co-isolated protein family Mtp PF03821.16 KFR01728.1 - 1.8e-11 44.1 5.6 1.2e-06 28.3 1.1 2.0 1 1 1 2 2 2 2 Golgi 4-transmembrane spanning transporter Tetraspanin PF00335.20 KFR01728.1 - 0.015 15.0 1.3 0.015 15.0 1.3 1.9 1 1 1 2 2 2 0 Tetraspanin family DUF4728 PF15860.5 KFR01728.1 - 0.021 15.5 4.9 0.021 15.5 4.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4728) Ribosomal_L7Ae PF01248.26 KFR01729.1 - 2.8e-26 91.1 0.1 3.1e-26 90.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_6 PF13344.6 KFR01729.1 - 0.028 14.5 0.0 0.033 14.3 0.0 1.1 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Ribonuc_L-PSP PF01042.21 KFR01730.1 - 1.7e-38 131.3 0.1 1.9e-38 131.2 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Corona_6B_7B PF03262.13 KFR01730.1 - 0.038 13.4 0.0 0.048 13.1 0.0 1.1 1 0 0 1 1 1 0 Coronavirus 6B/7B protein Con-6 PF10346.9 KFR01730.1 - 0.069 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Conidiation protein 6 POP1 PF06978.11 KFR01731.1 - 9.3e-38 130.3 27.7 7.8e-22 78.3 1.8 2.8 2 1 1 3 3 3 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KFR01731.1 - 9.5e-27 93.2 1.9 1.2e-26 92.9 0.1 2.1 2 0 0 2 2 2 1 POPLD (NUC188) domain Mg_trans_NIPA PF05653.14 KFR01732.1 - 1.8e-94 316.2 25.1 2.1e-94 316.0 25.1 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KFR01732.1 - 0.00069 19.8 1.5 0.00069 19.8 1.5 3.4 3 1 1 4 4 4 1 EamA-like transporter family Ion_trans PF00520.31 KFR01733.1 - 5.4e-41 140.4 5.1 5.4e-41 140.4 5.1 1.4 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.22 KFR01733.1 - 2.4e-31 107.9 0.2 3.7e-30 104.1 0.1 2.5 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFR01733.1 - 3.6e-13 49.3 3.5 3.6e-13 49.3 3.5 2.1 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.5 KFR01733.1 - 0.082 13.0 0.1 0.32 11.1 0.0 2.0 1 1 1 2 2 2 0 BTB/POZ domain DUF2463 PF09591.10 KFR01733.1 - 9.4 6.0 10.4 0.34 10.8 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2463) Chorein_N PF12624.7 KFR01734.1 - 5e-28 97.5 0.1 2.1e-27 95.5 0.1 2.2 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 KFR01734.1 - 5.7e-28 97.9 0.3 2.9e-26 92.3 0.0 2.7 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 KFR01734.1 - 4.3e-10 39.4 7.2 1.9e-07 30.7 0.1 4.4 4 1 0 4 4 4 3 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 KFR01734.1 - 6.7e-06 26.1 3.0 2.9e-05 24.0 1.6 2.9 2 1 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal ATG_C PF09333.11 KFR01734.1 - 1.7e-05 25.1 0.1 6.5e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain COX6C PF02937.15 KFR01736.1 - 7.8e-31 106.0 1.8 8.5e-31 105.9 1.8 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIc RGS PF00615.19 KFR01737.1 - 7.1e-10 39.2 0.2 9.3e-10 38.8 0.2 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain HHH_3 PF12836.7 KFR01737.1 - 0.0059 16.8 0.0 0.046 14.0 0.0 2.2 2 1 0 2 2 2 1 Helix-hairpin-helix motif IBR PF01485.21 KFR01738.1 - 7.5e-06 26.1 5.1 7.5e-06 26.1 5.1 2.1 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain DNA_RNApol_7kD PF03604.13 KFR01739.1 - 1.7e-17 62.7 8.8 2.6e-17 62.2 8.8 1.3 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit A2L_zn_ribbon PF08792.10 KFR01739.1 - 0.00051 19.7 1.0 0.00092 18.9 1.0 1.4 1 0 0 1 1 1 1 A2L zinc ribbon domain Cytochrome_C7 PF14522.6 KFR01739.1 - 0.0042 17.0 0.4 0.0053 16.7 0.4 1.2 1 0 0 1 1 1 1 Cytochrome c7 and related cytochrome c DZR PF12773.7 KFR01739.1 - 0.0054 16.7 1.8 0.0069 16.4 1.8 1.3 1 0 0 1 1 1 1 Double zinc ribbon MCM_OB PF17207.3 KFR01739.1 - 0.0061 16.4 1.7 0.0063 16.4 1.7 1.0 1 0 0 1 1 1 1 MCM OB domain HypA PF01155.19 KFR01739.1 - 0.014 15.4 1.7 0.017 15.2 1.7 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_13 PF09855.9 KFR01739.1 - 0.11 12.7 0.6 0.11 12.7 0.6 1.7 1 1 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-Sec23_Sec24 PF04810.15 KFR01739.1 - 1.1 9.3 6.3 15 5.8 0.1 2.5 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger TPR_1 PF00515.28 KFR01740.1 - 1.4e-47 157.7 22.4 4.7e-06 26.2 0.1 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.17 KFR01740.1 - 7.4e-35 116.3 12.0 0.00056 19.8 0.0 9.8 8 1 1 9 9 9 9 Tetratricopeptide repeat TPR_8 PF13181.6 KFR01740.1 - 3.7e-20 70.4 19.0 0.0045 17.1 0.0 9.2 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 KFR01740.1 - 1.8e-17 63.2 0.6 5.8e-06 26.4 0.0 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat RPAP3_C PF13877.6 KFR01740.1 - 8.9e-17 61.4 0.0 2.7e-16 59.9 0.0 1.9 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_11 PF13414.6 KFR01740.1 - 3.6e-16 58.6 19.1 5.9e-06 25.9 0.0 7.5 7 1 1 8 8 8 4 TPR repeat TPR_12 PF13424.6 KFR01740.1 - 4e-16 59.1 11.5 0.11 12.8 0.7 8.5 5 3 3 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 KFR01740.1 - 2.8e-09 37.4 9.9 0.065 13.7 0.0 5.8 5 2 3 8 8 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFR01740.1 - 3e-09 37.4 0.1 0.0045 17.6 0.0 5.6 4 2 1 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFR01740.1 - 1.7e-08 34.4 19.2 0.019 15.0 0.2 7.0 5 2 2 7 7 7 4 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 KFR01740.1 - 9.8e-08 32.2 0.1 0.43 11.5 0.0 6.0 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFR01740.1 - 9.1e-06 25.7 16.9 0.46 11.0 0.8 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFR01740.1 - 2e-05 24.9 12.7 0.6 10.9 0.1 7.7 9 0 0 9 9 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFR01740.1 - 2e-05 24.7 13.2 0.13 12.5 2.4 4.1 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KFR01740.1 - 0.00011 22.0 8.0 0.082 12.8 0.1 5.9 7 0 0 7 7 7 1 Tetratricopeptide repeat DUF4919 PF16266.5 KFR01740.1 - 0.00022 21.3 4.9 0.12 12.3 0.0 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF4919) MIT PF04212.18 KFR01740.1 - 0.00031 20.8 15.4 3.9 7.6 0.1 6.7 5 2 1 7 7 7 2 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 KFR01740.1 - 0.0011 18.9 7.7 28 5.1 0.0 6.8 8 0 0 8 8 7 0 Tetratricopeptide repeat PCI PF01399.27 KFR01740.1 - 0.067 13.7 2.6 7.4 7.1 0.1 3.6 3 0 0 3 3 3 0 PCI domain Cys_box PF17869.1 KFR01740.1 - 0.22 11.7 3.0 6.3 7.0 0.1 3.4 3 0 0 3 3 3 0 Anosmin cysteine rich domain TPR_20 PF14561.6 KFR01740.1 - 0.29 11.5 0.1 0.29 11.5 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KFR01740.1 - 0.32 11.5 2.1 3.9 7.9 0.1 3.2 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation IBR PF01485.21 KFR01741.1 - 9.4e-19 67.4 28.5 1.9e-13 50.4 11.5 4.9 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KFR01741.1 - 0.0027 18.0 9.8 0.0027 18.0 9.8 4.6 4 1 1 5 5 5 1 Ring finger domain zf-C3HC4 PF00097.25 KFR01741.1 - 0.0029 17.4 9.3 0.0029 17.4 9.3 4.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFR01741.1 - 0.0053 16.7 8.1 0.0053 16.7 8.1 4.2 4 1 0 4 4 4 1 zinc-RING finger domain Ank_4 PF13637.6 KFR01743.1 - 6.7e-22 77.6 0.6 1.1e-10 41.8 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFR01743.1 - 1e-15 58.1 0.1 4.6e-13 49.6 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFR01743.1 - 1.3e-12 47.7 0.1 1e-10 41.6 0.2 3.0 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KFR01743.1 - 1.7e-11 44.0 4.3 0.00015 22.1 0.2 4.3 3 1 1 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KFR01743.1 - 3.1e-10 39.4 2.3 0.00069 19.9 0.1 4.6 5 0 0 5 5 5 3 Ankyrin repeat SNX17_FERM_C PF18116.1 KFR01744.1 - 8.6e-34 115.8 0.1 1.8e-33 114.8 0.1 1.6 1 0 0 1 1 1 1 Sorting Nexin 17 FERM C-terminal domain PX PF00787.24 KFR01744.1 - 3.2e-07 30.3 0.1 9.6e-07 28.8 0.1 1.9 1 0 0 1 1 1 1 PX domain DUF5100 PF17029.5 KFR01744.1 - 0.016 15.1 1.1 0.034 14.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5100) FERM_M PF00373.18 KFR01744.1 - 0.062 13.7 0.1 0.12 12.8 0.1 1.5 1 0 0 1 1 1 0 FERM central domain 14-3-3 PF00244.20 KFR01745.1 - 3.3e-107 357.1 8.4 3.7e-107 356.9 8.4 1.0 1 0 0 1 1 1 1 14-3-3 protein FliM PF02154.15 KFR01745.1 - 0.066 13.1 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Flagellar motor switch protein FliM CSN7a_helixI PF18392.1 KFR01745.1 - 0.072 13.0 1.7 0.19 11.7 0.7 2.1 1 1 1 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain Peptidase_C98 PF15499.6 KFR01745.1 - 0.075 12.5 0.3 0.13 11.7 0.3 1.5 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF4518 PF15008.6 KFR01745.1 - 0.44 9.7 3.6 6 6.0 3.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) 4F5 PF04419.14 KFR01746.1 - 7.1e-11 42.8 17.3 9.3e-11 42.4 17.3 1.2 1 0 0 1 1 1 1 4F5 protein family zf-met PF12874.7 KFR01746.1 - 1.9e-05 24.9 0.2 3e-05 24.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFR01746.1 - 0.0027 18.0 0.3 0.0045 17.2 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_12 PF18658.1 KFR01746.1 - 0.0069 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KFR01746.1 - 0.011 16.5 1.3 0.016 16.0 1.3 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger Ribosomal_L44 PF00935.19 KFR01746.1 - 0.013 15.9 4.0 0.016 15.7 4.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L44 DUF629 PF04780.12 KFR01746.1 - 0.02 13.4 1.4 0.021 13.4 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-met2 PF12907.7 KFR01746.1 - 0.052 13.7 4.8 0.37 11.0 4.8 2.2 1 1 0 1 1 1 0 Zinc-binding PLATZ PF04640.14 KFR01746.1 - 0.054 14.1 1.7 0.072 13.7 1.7 1.2 1 0 0 1 1 1 0 PLATZ transcription factor EF-hand_7 PF13499.6 KFR01747.1 - 3e-23 82.1 0.7 6.1e-12 45.8 0.0 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KFR01747.1 - 3.3e-20 70.1 4.8 2e-07 30.1 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFR01747.1 - 1.4e-18 65.2 1.4 1.6e-06 27.6 0.1 4.7 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KFR01747.1 - 2e-18 65.0 4.5 4.7e-06 25.9 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 KFR01747.1 - 1e-12 47.7 5.2 8.1e-07 28.8 0.2 4.1 3 2 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFR01747.1 - 5.7e-05 23.4 0.1 0.086 13.2 0.0 2.6 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFR01747.1 - 0.00078 19.4 0.3 0.15 12.1 0.0 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KFR01747.1 - 0.035 14.3 0.1 8.5 6.7 0.0 2.4 2 1 0 2 2 2 0 Dockerin type I domain Fe_hyd_SSU PF02256.17 KFR01747.1 - 0.08 13.0 0.2 7 6.8 0.0 2.9 2 1 1 3 3 3 0 Iron hydrogenase small subunit Ribonuc_red_sm PF00268.21 KFR01748.1 - 2.5e-123 411.0 0.6 3e-123 410.7 0.6 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain HECT PF00632.25 KFR01749.1 - 3.3e-65 220.6 0.0 5.5e-65 219.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) E3_UbLigase_EDD PF11547.8 KFR01749.1 - 1.2e-30 104.9 3.9 3.4e-30 103.5 3.9 1.8 1 0 0 1 1 1 1 E3 ubiquitin ligase EDD PABP PF00658.18 KFR01749.1 - 6.6e-20 71.1 0.0 1.4e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain HSP20 PF00011.21 KFR01750.1 - 2.2e-09 37.4 0.2 2.4e-09 37.2 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family zf-C2H2 PF00096.26 KFR01751.1 - 4.9e-12 45.6 23.6 0.00043 20.6 3.0 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFR01751.1 - 8.1e-10 38.7 22.1 2.8e-06 27.5 1.9 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR01751.1 - 6e-09 36.0 19.5 0.0033 18.1 1.8 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFR01751.1 - 0.00075 20.1 6.2 1.9 9.2 0.2 3.6 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-Di19 PF05605.12 KFR01751.1 - 0.039 14.3 6.0 0.17 12.2 1.2 2.7 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf_Hakai PF18408.1 KFR01751.1 - 0.071 12.8 0.5 0.071 12.8 0.5 2.7 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain zf-C2H2_8 PF15909.5 KFR01751.1 - 0.15 12.3 12.4 0.056 13.8 7.2 2.6 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-TRAF PF02176.18 KFR01751.1 - 0.32 11.7 4.3 0.2 12.4 1.0 2.4 1 1 0 1 1 1 0 TRAF-type zinc finger zf-C2HC_2 PF13913.6 KFR01751.1 - 3.3 7.7 7.7 5.7 7.0 0.3 3.5 2 1 1 3 3 3 0 zinc-finger of a C2HC-type Orn_Arg_deC_N PF02784.16 KFR01752.1 - 1.6e-77 260.2 0.0 2e-77 259.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KFR01752.1 - 2.6e-19 69.3 0.0 3.1e-19 69.0 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Frizzled PF01534.17 KFR01754.1 - 3e-118 394.6 17.8 4.2e-118 394.1 17.8 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 KFR01754.1 - 1.3e-23 83.7 4.8 3.7e-23 82.3 4.8 1.8 1 0 0 1 1 1 1 Fz domain Folate_rec PF03024.14 KFR01754.1 - 0.0096 15.8 2.5 0.0096 15.8 2.5 1.8 2 0 0 2 2 2 1 Folate receptor family LapA_dom PF06305.11 KFR01754.1 - 0.16 11.8 0.4 0.85 9.5 0.1 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain RseC_MucC PF04246.12 KFR01754.1 - 0.93 9.4 4.3 1 9.3 0.1 2.8 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Collagen PF01391.18 KFR01755.1 - 3.4e-07 29.9 6.9 5.6e-07 29.2 6.9 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Mito_carr PF00153.27 KFR01756.1 - 4.2e-62 206.1 3.3 1.3e-22 79.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sof1 PF04158.14 KFR01757.1 - 3.8e-35 120.0 9.8 6.2e-35 119.3 9.8 1.3 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KFR01757.1 - 2.3e-21 75.7 12.4 0.00043 21.0 0.1 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.11 KFR01757.1 - 2.5e-06 27.5 0.7 0.002 18.1 0.0 3.5 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KFR01757.1 - 1.2e-05 25.5 0.0 0.036 14.3 0.0 3.9 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFR01757.1 - 0.038 13.0 0.1 3.1 6.7 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DC_STAMP PF07782.13 KFR01758.1 - 5.1e-60 202.6 3.1 1.1e-59 201.6 3.1 1.6 1 0 0 1 1 1 1 DC-STAMP-like protein Holin_SPP1 PF04688.13 KFR01758.1 - 0.066 13.4 0.4 0.28 11.4 0.0 2.2 2 0 0 2 2 2 0 SPP1 phage holin DUF3094 PF11293.8 KFR01758.1 - 0.14 11.9 0.6 7.7 6.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) Amidohydro_1 PF01979.20 KFR01759.1 - 3.3e-35 122.0 0.2 4.7e-35 121.5 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFR01759.1 - 9.6e-15 55.0 1.2 3.8e-08 33.3 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_2 PF04909.14 KFR01759.1 - 0.0027 17.5 0.0 0.0042 16.9 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase AP_endonuc_2 PF01261.24 KFR01759.1 - 0.033 13.6 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel BrnT_toxin PF04365.13 KFR01759.1 - 0.11 12.8 0.1 0.71 10.3 0.0 2.3 3 0 0 3 3 3 0 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system CUB PF00431.20 KFR01760.1 - 7.6e-47 158.2 1.3 3.7e-25 88.4 0.0 2.8 3 0 0 3 3 3 2 CUB domain Ldl_recept_a PF00057.18 KFR01760.1 - 1.9e-36 124.0 85.0 3.1e-11 43.3 14.9 5.6 5 0 0 5 5 5 5 Low-density lipoprotein receptor domain class A zf-C2H2 PF00096.26 KFR01761.1 - 4.2e-10 39.5 50.6 0.011 16.1 0.3 8.8 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFR01761.1 - 6.4e-09 35.9 52.5 0.05 13.9 0.7 8.6 8 0 0 8 8 8 7 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KFR01761.1 - 4.6e-08 33.2 48.8 0.23 12.4 0.1 8.9 8 0 0 8 8 8 5 C2H2-type zinc finger zf-met PF12874.7 KFR01761.1 - 1.4e-07 31.6 51.0 0.0096 16.3 0.7 8.6 8 0 0 8 8 8 6 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFR01761.1 - 0.093 13.0 22.3 0.025 14.9 5.2 5.7 6 0 0 6 6 6 0 C2H2-type zinc ribbon GATA PF00320.27 KFR01761.1 - 0.45 10.2 4.2 14 5.4 0.0 3.6 3 0 0 3 3 3 0 GATA zinc finger zf-C2H2_3 PF13878.6 KFR01761.1 - 3.7 7.4 12.9 13 5.7 0.1 5.9 6 0 0 6 6 6 0 zinc-finger of acetyl-transferase ESCO TLD PF07534.16 KFR01763.1 - 1.7e-40 138.4 0.1 2e-40 138.2 0.1 1.0 1 0 0 1 1 1 1 TLD Costars PF14705.6 KFR01764.1 - 1.3e-32 111.8 0.0 2.6e-32 110.8 0.0 1.5 1 0 0 1 1 1 1 Costars DUF5610 PF18433.1 KFR01764.1 - 0.26 11.8 2.5 0.35 11.4 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5610) Fibrinogen_C PF00147.18 KFR01765.1 - 2.7e-69 233.3 5.0 3.7e-69 232.9 5.0 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain FapA PF03961.13 KFR01765.1 - 1 7.9 14.2 1.4 7.4 14.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A HlyD_2 PF12700.7 KFR01765.1 - 3.7 6.2 17.7 7.2 5.2 17.7 1.4 1 0 0 1 1 1 0 HlyD family secretion protein DUF4239 PF14023.6 KFR01765.1 - 3.9 7.1 8.4 5.8 6.6 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) JAKMIP_CC3 PF16034.5 KFR01765.1 - 5.8 6.8 28.4 0.78 9.6 15.1 2.3 1 1 1 2 2 2 0 JAKMIP CC3 domain MCU PF04678.13 KFR01765.1 - 6.1 6.9 12.1 3.9 7.5 9.8 1.9 1 1 0 1 1 1 0 Mitochondrial calcium uniporter LIM PF00412.22 KFR01811.1 - 6.9e-61 202.3 21.5 2.3e-17 63.0 3.2 4.0 4 0 0 4 4 4 4 LIM domain zf-dskA_traR PF01258.17 KFR01811.1 - 0.0007 19.5 37.7 0.0014 18.5 4.8 6.6 6 1 1 7 7 7 3 Prokaryotic dksA/traR C4-type zinc finger WRC PF08879.10 KFR01811.1 - 0.13 12.0 0.3 0.13 12.0 0.3 3.5 5 0 0 5 5 5 0 WRC 7tm_1 PF00001.21 KFR01824.1 - 1.8e-80 270.1 8.4 2.4e-80 269.7 8.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR01824.1 - 3.7e-15 56.0 5.9 8.7e-15 54.8 5.9 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFR01824.1 - 1.3e-05 25.1 11.2 1.7e-05 24.7 4.5 2.7 3 0 0 3 3 3 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFR01824.1 - 1.3e-05 25.0 10.4 1.3e-05 25.0 10.4 2.0 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFR01824.1 - 0.00096 18.6 4.2 0.0034 16.8 4.2 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Shisa PF13908.6 KFR01824.1 - 0.059 13.6 0.1 6.3 7.0 0.1 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF1980 PF09323.10 KFR01824.1 - 0.16 11.8 0.0 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) UL45 PF05473.12 KFR01824.1 - 0.59 9.8 3.0 0.73 9.4 0.1 2.3 2 1 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like TraL PF07178.11 KFR01824.1 - 3.3 8.2 7.0 4.9 7.7 0.2 3.2 3 0 0 3 3 3 0 TraL protein TPR_1 PF00515.28 KFR01825.1 - 2.9e-25 87.0 2.0 6.7e-07 28.9 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFR01825.1 - 5.5e-18 63.6 2.3 4.9e-05 23.1 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFR01825.1 - 4.7e-12 45.4 3.9 0.0033 17.1 0.0 3.4 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 KFR01825.1 - 5.3e-12 45.0 6.5 0.0018 18.3 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFR01825.1 - 9.9e-11 41.8 0.7 2.2e-05 24.7 0.3 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFR01825.1 - 2.2e-07 30.9 2.7 1.3e-06 28.4 1.8 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFR01825.1 - 4.1e-07 30.4 4.9 1.2e-05 25.7 1.2 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFR01825.1 - 8.9e-07 29.2 2.3 0.0017 19.0 0.7 3.3 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFR01825.1 - 9.4e-06 25.0 3.0 0.0019 17.5 0.3 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFR01825.1 - 1.5e-05 24.7 0.7 0.056 13.5 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFR01825.1 - 3e-05 24.6 0.9 0.009 16.7 0.8 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFR01825.1 - 8.3e-05 23.0 0.3 0.0051 17.4 0.3 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFR01825.1 - 0.00015 21.9 1.7 0.0041 17.4 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3856 PF12968.7 KFR01825.1 - 0.0055 16.8 0.7 0.47 10.5 0.7 3.0 1 1 0 1 1 1 1 Domain of Unknown Function (DUF3856) RPN7 PF10602.9 KFR01825.1 - 0.017 14.8 7.2 0.026 14.3 1.5 2.9 3 0 0 3 3 3 0 26S proteasome subunit RPN7 Fis1_TPR_C PF14853.6 KFR01825.1 - 0.038 14.1 2.4 1.4 9.1 0.1 3.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KFR01825.1 - 0.046 13.6 1.6 10 6.2 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat MG2 PF01835.19 KFR01825.1 - 0.14 12.6 0.0 0.43 11.1 0.0 1.9 2 0 0 2 2 2 0 MG2 domain DUF3870 PF12986.7 KFR01825.1 - 0.16 12.2 0.0 0.46 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) NYD-SP28_assoc PF14775.6 KFR01825.1 - 1 9.5 5.4 7.9 6.7 1.8 2.7 1 1 1 2 2 2 0 Sperm tail C-terminal domain PWWP PF00855.17 KFR01826.1 - 5.3e-12 46.0 0.0 5.3e-12 46.0 0.0 3.1 2 1 1 3 3 3 1 PWWP domain Lipocalin_7 PF14651.6 KFR01827.1 - 5.8e-60 200.8 1.0 6.5e-60 200.7 1.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family C1q PF00386.21 KFR01828.1 - 1.5e-38 131.8 0.0 1.9e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFR01828.1 - 1.3e-17 63.2 62.0 1.9e-09 37.1 36.2 2.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) BclA_C PF18573.1 KFR01828.1 - 0.0054 16.6 0.0 0.0074 16.2 0.0 1.2 1 0 0 1 1 1 1 BclA C-terminal domain Slu7 PF11708.8 KFR01829.1 - 2.3e-109 365.3 11.9 2.3e-109 365.3 11.9 2.9 3 1 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 KFR01829.1 - 0.026 14.2 0.3 0.053 13.3 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle Securin PF04856.13 KFR01830.1 - 4.8e-14 52.9 0.2 6.2e-14 52.5 0.2 1.1 1 0 0 1 1 1 1 Securin sister-chromatid separation inhibitor Med26_M PF15694.5 KFR01830.1 - 0.0076 16.3 0.4 0.0096 16.0 0.4 1.1 1 0 0 1 1 1 1 Mediator complex subunit 26 middle domain T4SS PF07996.11 KFR01830.1 - 0.043 14.2 0.1 0.058 13.8 0.1 1.1 1 0 0 1 1 1 0 Type IV secretion system proteins PhoLip_ATPase_C PF16212.5 KFR01831.1 - 3.4e-80 269.4 24.8 3.4e-80 269.4 24.8 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFR01831.1 - 3.6e-22 77.8 2.1 1.5e-21 75.9 2.1 2.1 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFR01831.1 - 9.1e-13 49.0 0.1 2.9e-06 27.7 0.2 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFR01831.1 - 5.6e-09 36.0 0.0 4.2e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFR01831.1 - 0.00025 20.6 0.0 0.00077 19.0 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFR01831.1 - 0.0032 17.3 1.1 0.012 15.3 0.1 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Neur_chan_memb PF02932.16 KFR01832.1 - 1.1e-47 163.1 0.8 5.2e-47 160.9 0.8 1.8 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFR01832.1 - 3e-41 141.2 0.3 5.1e-41 140.5 0.0 1.5 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.23 KFR01833.1 - 2.6e-44 151.2 0.1 3.5e-44 150.9 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFR01833.1 - 1.5e-38 133.2 6.4 2.6e-34 119.3 4.0 2.2 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Cyclin_N PF00134.23 KFR01833.1 - 0.029 14.1 0.4 0.053 13.3 0.4 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain DUF4396 PF14342.6 KFR01833.1 - 0.13 12.6 8.2 0.068 13.5 5.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4396) Neur_chan_LBD PF02931.23 KFR01834.1 - 6.9e-51 172.7 0.0 9.1e-51 172.4 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFR01834.1 - 2.2e-38 132.7 4.6 5.4e-31 108.5 4.9 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_memb PF02932.16 KFR01835.1 - 9.6e-40 137.1 9.2 5.6e-37 128.1 3.3 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFR01835.1 - 2.1e-39 135.2 1.9 2.8e-39 134.8 1.9 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Cyclin_N PF00134.23 KFR01836.1 - 1.2e-21 76.7 0.1 3.1e-21 75.4 0.1 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFR01836.1 - 0.022 14.8 2.7 0.047 13.8 1.6 2.0 2 0 0 2 2 2 0 Cyclin, C-terminal domain HMMR_N PF15905.5 KFR01837.1 - 2.3e-98 329.7 62.1 2.3e-98 329.7 62.1 4.5 2 1 3 5 5 5 1 Hyaluronan mediated motility receptor N-terminal HMMR_C PF15908.5 KFR01837.1 - 9.9e-60 201.3 18.4 9.9e-60 201.3 18.4 6.5 2 1 3 6 6 6 1 Hyaluronan mediated motility receptor C-terminal RmlD_sub_bind PF04321.17 KFR01838.1 - 2.4e-85 286.1 0.0 2.7e-85 285.9 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KFR01838.1 - 1.3e-22 80.5 0.0 1.7e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFR01838.1 - 2.9e-10 39.8 0.2 1.7e-07 30.7 0.1 2.8 1 1 0 2 2 2 2 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KFR01838.1 - 2.3e-09 37.1 0.1 1.1e-08 34.9 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KFR01838.1 - 1e-05 24.8 0.3 0.0028 16.9 0.0 2.7 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.25 KFR01838.1 - 0.015 14.8 0.0 0.59 9.6 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase Ten_N PF06484.12 KFR01839.1 - 4.3e-33 115.7 3.1 4.8e-33 115.6 3.1 1.0 1 0 0 1 1 1 1 Teneurin Intracellular Region Ten_N PF06484.12 KFR01840.1 - 1.1e-66 226.2 15.4 1.7e-66 225.6 15.4 1.3 1 0 0 1 1 1 1 Teneurin Intracellular Region Tox-GHH PF15636.6 KFR01840.1 - 3.9e-31 106.9 0.5 7.1e-31 106.0 0.5 1.4 1 0 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin EGF_2 PF07974.13 KFR01840.1 - 2.6e-22 78.9 159.9 8.1e-05 22.9 9.3 9.5 9 0 0 9 9 9 8 EGF-like domain RHS_repeat PF05593.14 KFR01840.1 - 2.3e-13 50.3 34.7 0.00086 19.8 2.2 10.2 9 2 2 11 11 11 4 RHS Repeat NHL PF01436.21 KFR01840.1 - 6.7e-08 32.2 1.2 0.0094 16.0 0.0 5.6 5 0 0 5 5 5 1 NHL repeat CarboxypepD_reg PF13620.6 KFR01840.1 - 0.00015 21.9 0.2 0.00072 19.8 0.1 2.3 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF5640 PF18692.1 KFR01840.1 - 0.13 12.3 1.8 3.1 7.9 0.1 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5640) Pox_T4_C PF04490.12 KFR01840.1 - 0.2 11.8 1.4 0.53 10.4 1.4 1.7 1 0 0 1 1 1 0 Poxvirus T4 protein, C terminus DUF2283 PF10049.9 KFR01840.1 - 1.9 8.8 4.9 22 5.4 0.0 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF2283) tRNA-synt_1d PF00750.19 KFR01842.1 - 6.6e-158 525.2 0.0 8.6e-158 524.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) Arg_tRNA_synt_N PF03485.16 KFR01842.1 - 1.6e-23 83.1 0.8 4.3e-23 81.7 0.1 2.2 3 0 0 3 3 3 1 Arginyl tRNA synthetase N terminal domain DALR_1 PF05746.15 KFR01842.1 - 3.8e-21 75.5 0.2 9.3e-21 74.2 0.2 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain tRNA-synt_1e PF01406.19 KFR01842.1 - 0.0075 15.6 0.1 0.03 13.7 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Cnn_1N PF07989.11 KFR01842.1 - 0.0079 16.3 0.4 0.039 14.1 0.4 2.2 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 tRNA-synt_1 PF00133.22 KFR01842.1 - 0.12 10.6 0.0 0.2 9.9 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) Fumble PF03630.14 KFR01843.1 - 3.9e-117 391.1 0.0 4.4e-117 390.9 0.0 1.0 1 0 0 1 1 1 1 Fumble LRR_8 PF13855.6 KFR01844.1 - 1.1e-84 278.2 51.7 2.2e-15 56.2 0.6 9.5 4 3 5 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 KFR01844.1 - 4.8e-34 115.8 57.5 5.4e-05 23.5 0.1 11.6 8 3 2 12 12 12 11 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFR01844.1 - 5.5e-34 116.9 10.7 1e-10 41.6 1.0 4.6 4 0 0 4 4 4 4 BspA type Leucine rich repeat region (6 copies) EGF PF00008.27 KFR01844.1 - 1e-25 89.6 110.7 1.1e-06 28.8 5.1 9.5 10 0 0 10 10 8 6 EGF-like domain LRR_9 PF14580.6 KFR01844.1 - 2.7e-22 79.1 19.6 2.1e-06 27.3 1.1 5.4 4 1 1 5 5 5 5 Leucine-rich repeat LRRNT PF01462.18 KFR01844.1 - 2.7e-19 68.4 44.1 6e-09 35.3 3.3 7.4 7 0 0 7 7 7 3 Leucine rich repeat N-terminal domain Laminin_G_2 PF02210.24 KFR01844.1 - 3.4e-18 66.4 0.1 5.5e-18 65.8 0.1 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFR01844.1 - 1.9e-14 54.0 0.1 3e-14 53.3 0.1 1.3 1 0 0 1 1 1 1 Laminin G domain hEGF PF12661.7 KFR01844.1 - 8.3e-14 51.6 99.2 1.1e-06 29.0 4.9 10.7 11 0 0 11 11 9 6 Human growth factor-like EGF LRRCT PF01463.24 KFR01844.1 - 5.2e-12 45.3 13.3 0.037 14.6 0.0 6.3 6 0 0 6 6 5 4 Leucine rich repeat C-terminal domain LRR_1 PF00560.33 KFR01844.1 - 0.011 16.2 50.4 8 7.4 0.0 15.1 15 3 0 15 15 13 0 Leucine Rich Repeat EGF_CA PF07645.15 KFR01844.1 - 0.014 15.6 5.6 0.014 15.6 5.6 9.7 7 1 3 10 10 7 0 Calcium-binding EGF domain Laminin_G_3 PF13385.6 KFR01844.1 - 0.052 13.7 0.0 0.081 13.1 0.0 1.3 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily LRR_6 PF13516.6 KFR01844.1 - 3.5 7.9 0.0 3.5 7.9 0.0 10.3 12 0 0 12 12 11 0 Leucine Rich repeat TPKR_C2 PF16920.5 KFR01844.1 - 8.7 6.6 28.9 0.98 9.6 0.2 7.0 7 0 0 7 7 7 0 Tyrosine-protein kinase receptor C2 Ig-like domain DUF1949 PF09186.11 KFR01845.1 - 0.15 11.9 1.3 0.45 10.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) zf-CCCH_6 PF18585.1 KFR01845.1 - 8.2 6.4 7.3 11 6.0 0.2 4.2 3 0 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 DOCK_N PF16172.5 KFR01846.1 - 1.4e-114 383.0 0.1 3e-114 381.9 0.1 1.6 1 0 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 KFR01846.1 - 1.5e-99 334.1 8.6 1.5e-99 334.1 8.6 2.6 2 2 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 KFR01846.1 - 9.4e-59 198.5 0.0 8.4e-58 195.4 0.0 2.6 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins SH3_1 PF00018.28 KFR01846.1 - 0.00038 20.0 0.0 0.00076 19.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFR01846.1 - 0.0072 16.2 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_14 PF18343.1 KFR01846.1 - 0.014 15.5 0.0 0.069 13.3 0.0 2.2 1 0 0 1 1 1 0 Dda helicase SH3 domain SH3_2 PF07653.17 KFR01846.1 - 0.024 14.3 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain FliX PF10768.9 KFR01846.1 - 0.081 13.5 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 Class II flagellar assembly regulator FAM196 PF15265.6 KFR01847.1 - 2.6e-150 502.2 26.0 3e-150 502.0 26.0 1.0 1 0 0 1 1 1 1 FAM196 family Forkhead PF00250.18 KFR01848.1 - 7.7e-40 135.0 0.0 9.1e-40 134.8 0.0 1.1 1 0 0 1 1 1 1 Forkhead domain CaKB PF03185.15 KFR01849.1 - 2.6e-73 245.8 0.3 3e-73 245.7 0.3 1.0 1 0 0 1 1 1 1 Calcium-activated potassium channel, beta subunit zf-LITAF-like PF10601.9 KFR01849.1 - 0.48 10.7 2.7 1 9.7 0.3 2.2 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain EF-hand_7 PF13499.6 KFR01850.1 - 4e-24 84.8 1.6 1.7e-18 66.8 0.3 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFR01850.1 - 5.7e-18 63.1 6.2 2.5e-07 29.8 0.2 4.0 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFR01850.1 - 8e-16 56.6 5.5 0.00029 20.5 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KFR01850.1 - 1.5e-15 56.7 3.4 5.3e-05 23.0 0.0 3.5 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KFR01850.1 - 2.1e-12 46.0 4.1 2.9e-05 23.4 0.1 3.7 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.9 KFR01850.1 - 2.7e-06 27.7 1.2 0.00054 20.3 1.0 3.0 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFR01850.1 - 0.0015 18.5 1.6 0.068 13.1 0.1 2.8 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFR01850.1 - 0.0025 18.1 0.1 7.4 7.0 0.0 3.7 4 0 0 4 4 4 1 EF-hand domain Dockerin_1 PF00404.18 KFR01850.1 - 0.095 12.9 0.6 1.2 9.4 0.5 2.3 1 1 1 2 2 2 0 Dockerin type I domain Troponin PF00992.20 KFR01850.1 - 0.14 12.5 0.1 0.4 11.0 0.1 1.8 1 1 1 2 2 2 0 Troponin Caleosin PF05042.13 KFR01850.1 - 0.32 10.9 3.2 6.2 6.7 0.1 2.9 2 1 0 2 2 2 0 Caleosin related protein Neur_chan_LBD PF02931.23 KFR01851.1 - 1.2e-46 158.9 0.1 2.5e-46 157.9 0.1 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFR01851.1 - 6.9e-21 75.4 11.0 1.8e-19 70.7 6.2 2.2 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region I-set PF07679.16 KFR01852.1 - 5.5e-14 52.0 0.0 8.6e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR01852.1 - 1.3e-13 51.3 0.0 2.4e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain IGFBP PF00219.18 KFR01852.1 - 1.4e-06 28.8 20.5 1.4e-06 28.8 20.5 2.2 2 0 0 2 2 2 1 Insulin-like growth factor binding protein Kazal_1 PF00050.21 KFR01852.1 - 3.6e-06 26.9 1.7 3.6e-06 26.9 1.7 2.2 2 1 0 2 2 2 1 Kazal-type serine protease inhibitor domain ig PF00047.25 KFR01852.1 - 1.1e-05 25.5 0.0 3.3e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFR01852.1 - 0.00015 22.0 0.0 0.0003 21.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFR01852.1 - 0.00032 20.9 0.0 0.0012 19.0 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin V-set domain Kazal_2 PF07648.15 KFR01852.1 - 0.00034 20.7 2.7 0.00034 20.7 2.7 2.7 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain IBN_N PF03810.19 KFR01853.1 - 2.4e-10 40.2 1.6 1.2e-09 37.9 0.2 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain FGF PF00167.18 KFR01854.1 - 1.1e-42 145.0 0.1 1.6e-42 144.6 0.1 1.2 1 0 0 1 1 1 1 Fibroblast growth factor WD40 PF00400.32 KFR01855.1 - 6.7e-40 134.4 17.9 6.7e-07 29.9 0.2 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat Beta-TrCP_D PF12125.8 KFR01855.1 - 9.9e-26 89.4 2.3 2.1e-25 88.3 2.3 1.6 1 0 0 1 1 1 1 D domain of beta-TrCP ANAPC4_WD40 PF12894.7 KFR01855.1 - 3.6e-11 43.2 2.7 0.0095 16.2 0.1 4.6 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 KFR01855.1 - 1.1e-09 38.0 0.1 2.6e-09 36.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFR01855.1 - 1.4e-06 28.0 0.0 4.2e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 KFR01855.1 - 1.8e-06 27.5 0.1 0.0082 15.5 0.4 2.5 1 1 1 2 2 2 2 WD40-like domain Nup160 PF11715.8 KFR01855.1 - 7.8e-05 21.5 10.3 0.095 11.3 0.2 4.5 3 2 3 6 6 6 2 Nucleoporin Nup120/160 DUF5046 PF16465.5 KFR01855.1 - 0.0092 15.5 0.2 0.91 8.9 0.2 3.2 1 1 2 3 3 3 1 Domain of unknown function (DUF5046) eIF2A PF08662.11 KFR01855.1 - 0.022 14.7 0.0 4.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF4508 PF14969.6 KFR01855.1 - 0.09 13.0 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) DUF1513 PF07433.11 KFR01855.1 - 0.12 11.5 0.0 1.2 8.1 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1513) Prot_ATP_ID_OB PF16450.5 KFR01855.1 - 0.14 12.1 0.2 15 5.7 0.0 3.2 2 1 0 2 2 2 0 Proteasomal ATPase OB C-terminal domain eRF1_2 PF03464.15 KFR01856.1 - 1.4e-46 158.1 0.1 2.4e-46 157.3 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KFR01856.1 - 4.3e-39 133.5 0.3 9.3e-39 132.4 0.3 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KFR01856.1 - 3.7e-18 65.8 0.0 7.1e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 KFR01856.1 - 8.8e-11 42.2 0.1 1.3e-10 41.7 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 KFR01856.1 - 7.1e-09 36.0 0.0 1.2e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Ribosomal_L7Ae PF01248.26 KFR01856.1 - 0.011 15.5 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF4825 PF16107.5 KFR01856.1 - 0.12 12.5 0.1 3.9 7.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4825) HSP70 PF00012.20 KFR01857.1 - 2.8e-257 854.7 7.9 3.2e-257 854.6 7.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFR01857.1 - 1.7e-18 66.5 1.7 5.9e-16 58.2 0.3 2.4 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KFR01857.1 - 1.4e-05 24.9 0.1 2.9e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KFR01857.1 - 0.014 15.8 3.7 7 7.1 0.1 3.7 3 2 0 3 3 3 0 Cell division protein FtsA Vinculin PF01044.19 KFR01858.1 - 0 1038.2 37.6 4.3e-215 717.1 24.4 2.1 1 1 1 2 2 2 2 Vinculin family DUF4685 PF15737.5 KFR01858.1 - 0.17 12.3 1.7 33 4.9 0.3 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) Peptidase_C5 PF00770.18 KFR01858.1 - 0.19 11.4 0.0 0.43 10.2 0.0 1.5 1 0 0 1 1 1 0 Adenovirus endoprotease LRR_8 PF13855.6 KFR01859.1 - 2.5e-48 161.7 53.4 5.5e-16 58.1 6.7 5.1 2 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KFR01859.1 - 5.2e-25 87.1 38.1 3.8e-06 27.1 1.1 6.3 4 2 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFR01859.1 - 1.4e-21 76.7 0.1 6.1e-10 39.2 0.0 3.4 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFR01859.1 - 9.4e-12 44.8 10.7 0.00021 20.9 0.4 3.6 1 1 0 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 KFR01859.1 - 3.4e-08 32.9 35.4 0.98 10.2 0.2 9.9 10 0 0 10 10 10 4 Leucine Rich Repeat LRR_6 PF13516.6 KFR01859.1 - 0.0095 15.9 41.7 4.5 7.6 0.1 10.1 10 0 0 10 10 10 3 Leucine Rich repeat LRRNT PF01462.18 KFR01859.1 - 0.019 14.6 2.0 0.019 14.6 2.0 2.6 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain LRR_2 PF07723.13 KFR01859.1 - 8.5 7.2 17.2 61 4.5 0.1 6.5 6 0 0 6 6 6 0 Leucine Rich Repeat Fes1 PF08609.10 KFR01860.1 - 5.2e-07 30.5 1.8 5.2e-07 30.5 1.8 1.8 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 CDC14 PF08045.11 KFR01860.1 - 0.0024 17.0 3.7 0.0046 16.1 0.2 2.4 2 0 0 2 2 2 1 Cell division control protein 14, SIN component DUF4704 PF15787.5 KFR01860.1 - 0.021 14.1 0.9 0.041 13.1 0.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4704) MSP7_C PF12948.7 KFR01860.1 - 0.032 14.9 1.8 0.38 11.4 1.9 2.2 2 0 0 2 2 2 0 MSP7-like protein C-terminal domain DUF2120 PF09893.9 KFR01860.1 - 0.32 11.1 3.8 0.17 12.0 1.4 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) RRM_1 PF00076.22 KFR01861.1 - 2.7e-09 36.7 0.0 0.00033 20.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFR01861.1 - 5.7e-07 29.2 0.1 0.0096 15.5 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTU2 PF10288.9 KFR01861.1 - 1.6 9.0 0.0 1.6 9.0 0.0 3.8 3 1 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-C2H2_jaz PF12171.8 KFR01861.1 - 2.7 8.4 10.0 2.1 8.8 1.7 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Spore_coat_CotO PF14153.6 KFR01861.1 - 4.1 7.3 22.3 1.2 9.0 7.2 2.4 2 0 0 2 2 2 0 Spore coat protein CotO DUF908 PF06012.12 KFR01861.1 - 7 5.9 9.1 0.97 8.8 1.6 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) PAM2 PF07145.15 KFR01862.1 - 1.5e-07 30.6 0.8 3.5e-07 29.5 0.8 1.7 1 0 0 1 1 1 1 Ataxin-2 C-terminal region DUF3911 PF13050.6 KFR01862.1 - 0.019 15.1 0.2 0.043 13.9 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3911) Xan_ur_permease PF00860.20 KFR01863.1 - 1.1e-85 287.7 26.8 1.4e-85 287.4 26.8 1.1 1 0 0 1 1 1 1 Permease family DUF3456 PF11938.8 KFR01864.1 - 7.3e-05 23.3 0.0 0.0079 16.7 0.0 2.8 1 1 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP MCR PF18509.1 KFR01864.1 - 0.016 14.8 0.2 0.016 14.8 0.2 2.2 3 0 0 3 3 3 0 Magnetochrome domain DnaJ PF00226.31 KFR01865.1 - 3.4e-25 87.9 1.4 4e-25 87.7 0.2 1.8 2 0 0 2 2 2 1 DnaJ domain DUF1977 PF09320.11 KFR01865.1 - 4.6e-25 87.9 3.4 4.6e-25 87.9 3.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) GntP_permease PF02447.16 KFR01865.1 - 0.021 13.5 0.0 0.026 13.2 0.0 1.1 1 0 0 1 1 1 0 GntP family permease O-antigen_lig PF13425.6 KFR01865.1 - 0.067 12.0 1.7 0.09 11.6 1.7 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Sel1 PF08238.12 KFR01866.1 - 1.5e-20 73.2 19.9 3e-06 27.7 0.3 5.3 5 0 0 5 5 5 4 Sel1 repeat TPR_6 PF13174.6 KFR01866.1 - 0.043 14.5 6.4 7.2 7.5 0.1 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFR01866.1 - 8.3 6.8 15.3 5.4 7.4 0.0 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat Cadherin PF00028.17 KFR01868.1 - 9e-118 385.1 4.3 6.5e-23 81.0 0.0 7.3 7 0 0 7 7 7 7 Cadherin domain Protocadherin PF08374.11 KFR01868.1 - 2.4e-81 272.9 1.5 4.7e-81 271.9 1.5 1.5 1 0 0 1 1 1 1 Protocadherin Cadherin_2 PF08266.12 KFR01868.1 - 5e-14 51.9 0.0 2.2e-05 24.2 0.0 6.0 6 1 0 6 6 6 3 Cadherin-like Cadherin_3 PF16184.5 KFR01868.1 - 1.9e-07 31.0 8.2 0.75 9.8 0.1 6.0 6 0 0 6 6 6 3 Cadherin-like TMEM154 PF15102.6 KFR01868.1 - 0.0085 16.0 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family Syndecan PF01034.20 KFR01868.1 - 0.077 12.9 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 KFR01868.1 - 0.087 13.7 0.0 0.21 12.5 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MLANA PF14991.6 KFR01868.1 - 0.089 13.1 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A Mid2 PF04478.12 KFR01868.1 - 0.093 12.6 0.8 0.26 11.1 0.0 2.1 3 0 0 3 3 3 0 Mid2 like cell wall stress sensor FlgD_ig PF13860.6 KFR01868.1 - 0.12 12.3 1.6 1.6 8.7 0.1 3.5 3 0 0 3 3 3 0 FlgD Ig-like domain Adeno_E3_CR2 PF02439.15 KFR01868.1 - 0.35 10.6 2.1 0.87 9.4 2.1 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Lamprin PF06403.11 KFR01870.1 - 1.7e-05 24.8 13.5 0.004 17.1 5.6 2.0 1 1 1 2 2 2 2 Lamprin Chorion_1 PF01723.16 KFR01870.1 - 0.013 15.5 25.4 1.1e+02 2.7 25.4 2.2 1 1 0 1 1 1 0 Chorion protein 7tm_1 PF00001.21 KFR01871.1 - 2.4e-28 99.2 15.6 4.3e-28 98.4 15.6 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFR01871.1 - 0.046 13.0 8.8 0.04 13.2 1.8 2.1 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw Pox_I5 PF04713.12 KFR01871.1 - 0.28 11.3 5.1 0.59 10.2 5.1 1.5 1 0 0 1 1 1 0 Poxvirus protein I5 COX7C PF02935.16 KFR01871.1 - 1.2 9.5 3.9 0.53 10.6 0.4 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc SH3_1 PF00018.28 KFR01872.1 - 3.4e-23 81.0 0.2 2.1e-11 43.3 0.1 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KFR01872.1 - 5.1e-21 74.3 1.3 1.3e-10 41.0 0.1 2.8 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KFR01872.1 - 1.5e-19 69.4 0.1 7.4e-09 35.2 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 KFR01872.1 - 4.8e-15 55.6 0.1 4.8e-15 55.6 0.1 2.8 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_3 PF08239.11 KFR01872.1 - 4.4e-05 23.7 0.2 0.0001 22.5 0.2 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain hSH3 PF14603.6 KFR01872.1 - 0.00015 22.2 0.5 0.0004 20.8 0.0 1.9 2 0 0 2 2 2 1 Helically-extended SH3 domain Spc24 PF08286.11 KFR01872.1 - 4.1 7.7 7.1 30 4.9 2.4 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 RELT PF12606.8 KFR01873.1 - 1.8e-23 81.2 1.7 3.6e-23 80.3 1.7 1.5 1 0 0 1 1 1 1 Tumour necrosis factor receptor superfamily member 19 DUF5383 PF17355.2 KFR01873.1 - 0.25 11.7 1.1 1.4 9.3 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5383) Hist_deacetyl PF00850.19 KFR01874.1 - 2.3e-81 273.6 0.1 3.3e-81 273.1 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain WD40 PF00400.32 KFR01876.1 - 7.3e-19 67.8 17.0 3.7e-10 40.2 0.7 4.4 4 1 1 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR01876.1 - 6e-08 32.9 0.6 6.1e-05 23.3 0.1 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2387 PF09526.10 KFR01876.1 - 0.11 12.6 10.5 0.32 11.2 0.6 3.2 3 0 0 3 3 3 0 Probable metal-binding protein (DUF2387) Trypsin PF00089.26 KFR01879.1 - 6.3e-69 232.1 0.3 7.1e-69 232.0 0.3 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFR01879.1 - 3.2e-09 37.8 0.0 4.3e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFR01879.1 - 6.4e-08 33.0 0.0 1.5e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Hexapep PF00132.24 KFR01885.1 - 0.00031 20.3 3.7 0.00031 20.3 3.7 2.3 3 0 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) RRM_1 PF00076.22 KFR01886.1 - 5.8e-12 45.3 0.0 8.7e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIE_beta PF02186.15 KFR01887.1 - 7.1e-22 77.5 0.2 7.1e-22 77.5 0.2 2.3 3 0 0 3 3 3 1 TFIIE beta subunit core domain TFA2_Winged_2 PF18121.1 KFR01887.1 - 2.4e-10 40.0 0.1 5.4e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 PDZ PF00595.24 KFR01887.1 - 0.043 14.2 0.1 0.096 13.0 0.1 1.5 1 0 0 1 1 1 0 PDZ domain EF-hand_11 PF08976.11 KFR01887.1 - 0.045 14.6 0.0 0.081 13.8 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain DUF4713 PF15831.5 KFR01888.1 - 5.8e-22 77.9 7.5 7.1e-22 77.6 7.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4713) EVC2_like PF12297.8 KFR01888.1 - 0.081 11.6 0.1 0.085 11.5 0.1 1.0 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein DNA_pol_A_exo1 PF01612.20 KFR01889.1 - 3.9e-32 111.4 0.0 7.3e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease RQC PF09382.10 KFR01889.1 - 1.3e-17 63.6 0.0 4.1e-17 62.0 0.0 1.8 1 0 0 1 1 1 1 RQC domain Helicase_C PF00271.31 KFR01889.1 - 2e-16 60.3 0.0 9.9e-16 58.1 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFR01889.1 - 8.2e-16 58.3 0.0 5.1e-15 55.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase HTH_40 PF14493.6 KFR01889.1 - 3.1e-12 46.8 0.1 1.1e-11 45.0 0.1 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain HRDC PF00570.23 KFR01889.1 - 1.3e-11 44.3 0.2 5.1e-11 42.4 0.1 2.2 2 0 0 2 2 2 1 HRDC domain RecQ_Zn_bind PF16124.5 KFR01889.1 - 3.6e-08 34.0 1.8 3.6e-08 34.0 1.8 2.3 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 KFR01889.1 - 0.0011 18.9 0.0 0.0035 17.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NPV_P10 PF05531.12 KFR01889.1 - 0.11 13.0 0.1 0.31 11.5 0.1 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein PurA PF04845.13 KFR01890.1 - 1.1e-106 355.1 0.0 1.3e-106 354.9 0.0 1.0 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein DUF3276 PF11680.8 KFR01890.1 - 0.0086 16.2 2.3 4.5 7.4 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3276) Metallophos PF00149.28 KFR01891.1 - 3.2e-35 122.5 0.5 5.4e-35 121.8 0.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFR01891.1 - 0.0043 17.5 0.4 0.01 16.3 0.4 1.6 1 1 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 KFR01891.1 - 0.021 14.5 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF5378 PF17349.2 KFR01891.1 - 0.088 12.1 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Pyr_redox_2 PF07992.14 KFR01892.1 - 5.8e-48 163.6 0.0 1e-47 162.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFR01892.1 - 6.5e-35 119.7 0.3 1.1e-34 119.0 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFR01892.1 - 6.9e-18 65.0 0.4 1.8e-17 63.7 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFR01892.1 - 6.3e-08 32.2 0.0 8.4e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFR01892.1 - 0.0032 16.7 0.0 0.0048 16.1 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) RVT_1 PF00078.27 KFR01904.1 - 0.002 17.7 0.0 0.0047 16.5 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Protocadherin PF08374.11 KFR01914.1 - 0.0013 18.7 0.0 0.0018 18.3 0.0 1.2 1 0 0 1 1 1 1 Protocadherin Chordopox_A13L PF05961.11 KFR01914.1 - 0.0015 18.7 1.7 0.0034 17.6 1.7 1.8 1 1 0 1 1 1 1 Chordopoxvirus A13L protein EphA2_TM PF14575.6 KFR01914.1 - 0.0017 19.2 0.0 0.0021 18.9 0.0 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 KFR01914.1 - 0.028 14.3 0.6 0.047 13.6 0.6 1.3 1 0 0 1 1 1 0 Syndecan domain DUF4381 PF14316.6 KFR01914.1 - 0.039 14.2 0.0 0.055 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TRP PF06011.12 KFR01914.1 - 0.066 11.9 0.0 0.075 11.7 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Flp1_like PF16982.5 KFR01914.1 - 0.088 12.2 0.7 0.14 11.6 0.7 1.3 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain PTP_tm PF18861.1 KFR01914.1 - 0.74 9.8 3.0 1.2 9.1 3.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J PMP1_2 PF08114.11 KFR01914.1 - 9.1 6.1 8.2 21 4.9 8.2 1.6 1 1 0 1 1 1 0 ATPase proteolipid family C2-set_2 PF08205.12 KFR01915.1 - 2.8e-20 72.2 0.5 1.7e-18 66.5 0.1 2.6 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFR01915.1 - 4.2e-19 68.7 1.0 8.8e-16 58.0 0.0 3.4 3 1 0 3 3 3 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFR01915.1 - 1.5e-17 64.0 1.5 3.3e-07 30.8 0.1 3.4 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFR01915.1 - 3e-17 62.6 0.6 4.5e-07 29.9 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFR01915.1 - 3e-14 53.1 3.0 2e-06 28.0 0.1 3.8 3 1 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFR01915.1 - 6.8e-08 32.5 0.1 0.00082 19.4 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_6 PF18452.1 KFR01915.1 - 0.0021 17.6 0.0 2.4 7.8 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.15 KFR01915.1 - 0.022 15.1 0.5 1.3 9.5 0.0 2.7 2 0 0 2 2 2 0 Immunoglobulin C1-set domain OAF PF14941.6 KFR01916.1 - 3.5e-105 350.8 1.5 3.9e-105 350.7 1.5 1.0 1 0 0 1 1 1 1 Transcriptional regulator, Out at first Pou PF00157.17 KFR01917.1 - 3.1e-38 129.6 0.6 6.7e-38 128.5 0.2 1.8 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KFR01917.1 - 1.5e-18 66.4 3.3 4e-18 65.0 3.3 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFR01917.1 - 0.071 13.0 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain HTH_3 PF01381.22 KFR01917.1 - 0.14 12.2 0.2 1.4 9.1 0.0 2.3 2 1 0 2 2 2 0 Helix-turn-helix RGS-like PF09128.11 KFR01920.1 - 1.5e-84 282.4 2.4 1.5e-84 282.4 2.4 3.3 4 0 0 4 4 4 2 Regulator of G protein signalling-like domain PH_16 PF17838.1 KFR01920.1 - 4.5e-45 152.5 1.1 8.6e-45 151.6 1.1 1.5 1 0 0 1 1 1 1 PH domain RhoGEF PF00621.20 KFR01920.1 - 4.8e-38 131.2 1.6 4.8e-38 131.2 1.6 2.3 3 0 0 3 3 3 1 RhoGEF domain PDZ PF00595.24 KFR01920.1 - 1e-12 48.2 0.2 7.5e-12 45.4 0.5 2.4 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFR01920.1 - 1.2e-12 47.5 0.1 4e-12 45.8 0.1 2.0 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFR01920.1 - 1.7e-07 31.4 0.2 6.2e-07 29.6 0.2 2.0 1 0 0 1 1 1 1 PDZ domain PH_13 PF16652.5 KFR01920.1 - 5.4e-07 29.6 0.3 1.7e-06 28.0 0.3 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Tricorn_PDZ PF14685.6 KFR01920.1 - 0.1 12.6 0.4 0.38 10.8 0.1 2.2 2 0 0 2 2 2 0 Tricorn protease PDZ domain AAA_23 PF13476.6 KFR01920.1 - 1.1 9.7 0.0 1.1 9.7 0.0 3.5 4 1 0 4 4 4 0 AAA domain ANF_receptor PF01094.28 KFR01921.1 - 5e-61 206.8 0.0 8.3e-61 206.0 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 KFR01921.1 - 3.6e-48 163.2 0.1 5.7e-48 162.5 0.1 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFR01921.1 - 2.3e-44 150.2 0.0 5.4e-44 149.1 0.0 1.6 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFR01921.1 - 7.5e-21 74.6 0.0 1.4e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 LRR_9 PF14580.6 KFR01922.1 - 8.9e-12 44.9 2.7 7.6e-09 35.3 0.2 3.2 2 1 1 3 3 3 2 Leucine-rich repeat LRR_4 PF12799.7 KFR01922.1 - 1.3e-07 31.8 28.6 0.0028 18.0 4.7 5.8 2 2 5 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFR01922.1 - 2e-07 30.6 16.5 0.0027 17.4 2.1 4.3 1 1 4 5 5 5 5 Leucine rich repeat Ubiquitin_2 PF14560.6 KFR01922.1 - 2.3e-07 31.2 0.2 8e-07 29.4 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin-like domain ubiquitin PF00240.23 KFR01922.1 - 0.0021 17.7 0.5 0.019 14.7 0.5 2.3 1 1 0 1 1 1 1 Ubiquitin family LRR_6 PF13516.6 KFR01922.1 - 0.069 13.2 17.1 1.5 9.0 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich repeat PB1 PF00564.24 KFR01922.1 - 0.07 13.1 0.2 0.19 11.7 0.2 1.7 1 0 0 1 1 1 0 PB1 domain APG12 PF04110.13 KFR01922.1 - 0.093 13.1 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 LRR_1 PF00560.33 KFR01922.1 - 7.1 7.6 15.0 4.7 8.1 0.1 5.4 5 1 0 5 5 5 0 Leucine Rich Repeat FA_hydroxylase PF04116.13 KFR01923.1 - 8.7e-17 61.7 17.0 5.2e-16 59.2 15.9 2.0 1 1 1 2 2 2 2 Fatty acid hydroxylase superfamily Ldl_recept_a PF00057.18 KFR01924.1 - 6.6e-113 368.6 208.4 7.7e-14 51.6 7.5 12.3 12 0 0 12 12 12 11 Low-density lipoprotein receptor domain class A Sortilin-Vps10 PF15902.5 KFR01924.1 - 6.4e-112 374.6 0.0 1.1e-111 373.8 0.0 1.4 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KFR01924.1 - 5.8e-41 140.7 0.2 5.8e-41 140.7 0.2 5.5 4 1 1 5 5 1 1 Sortilin, neurotensin receptor 3, C-terminal fn3 PF00041.21 KFR01924.1 - 1.2e-32 112.1 16.1 4.7e-09 36.5 0.3 6.4 6 0 0 6 6 6 5 Fibronectin type III domain Ldl_recept_b PF00058.17 KFR01924.1 - 7.2e-24 84.0 6.1 2e-07 31.3 0.1 5.7 5 0 0 5 5 5 5 Low-density lipoprotein receptor repeat class B Interfer-bind PF09294.10 KFR01924.1 - 0.00012 22.4 14.6 1.3 9.4 0.1 5.5 5 0 0 5 5 5 2 Interferon-alpha/beta receptor, fibronectin type III BNR_6 PF15899.5 KFR01924.1 - 0.00031 20.5 5.0 0.51 10.5 0.8 3.5 2 0 0 2 2 2 2 BNR-Asp box repeat Pur_ac_phosph_N PF16656.5 KFR01924.1 - 0.00047 20.7 15.7 0.49 11.0 0.1 4.9 5 0 0 5 5 4 2 Purple acid Phosphatase, N-terminal domain BNR PF02012.20 KFR01924.1 - 0.0011 18.6 14.6 2.1 8.7 0.2 5.8 5 0 0 5 5 5 1 BNR/Asp-box repeat fn3_2 PF16893.5 KFR01924.1 - 0.013 15.6 5.1 2.5 8.3 0.0 4.6 5 1 1 6 6 6 0 Fibronectin type III domain DUF3377 PF11857.8 KFR01924.1 - 0.095 12.6 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) CHB_HEX_C PF03174.13 KFR01924.1 - 0.19 11.7 0.7 8.8 6.4 0.0 2.7 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain SH3_9 PF14604.6 KFR01925.1 - 1e-17 63.7 0.0 2.1e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain His_Phos_1 PF00300.22 KFR01925.1 - 4.1e-17 62.5 0.0 1.2e-16 61.0 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 2_5_RNA_ligase2 PF13563.6 KFR01925.1 - 5.1e-06 26.5 1.0 1.2e-05 25.2 0.5 1.8 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily SH3_1 PF00018.28 KFR01925.1 - 4.5e-05 23.0 0.0 9.4e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain LigT_PEase PF02834.16 KFR01925.1 - 6.1e-05 23.1 0.2 0.36 11.0 0.1 2.7 3 0 0 3 3 3 2 LigT like Phosphoesterase His_Phos_2 PF00328.22 KFR01925.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Homeodomain PF00046.29 KFR01926.1 - 4e-22 77.8 1.9 6e-22 77.3 1.9 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFR01926.1 - 0.056 13.3 0.0 0.056 13.3 0.0 2.5 2 0 0 2 2 2 0 Homeobox KN domain HSP70 PF00012.20 KFR01927.1 - 6.5e-265 880.0 12.3 7.4e-265 879.8 12.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFR01927.1 - 1.4e-18 66.8 0.5 4e-17 62.0 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KFR01927.1 - 0.0011 19.4 3.8 1.5 9.3 0.1 3.6 3 2 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 KFR01927.1 - 0.0018 18.0 0.0 0.005 16.6 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 KFR01927.1 - 0.012 15.1 0.1 4.9 6.6 0.0 2.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DDR PF08841.10 KFR01927.1 - 0.033 13.2 0.3 0.18 10.8 0.3 2.0 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain HORMA PF02301.18 KFR01927.1 - 0.081 12.5 1.2 0.2 11.2 1.2 1.6 1 0 0 1 1 1 0 HORMA domain MetOD2 PF18548.1 KFR01927.1 - 0.31 11.2 0.1 0.31 11.2 0.1 3.0 2 1 1 3 3 3 0 Metanogen output domain 2 V-set PF07686.17 KFR01928.1 - 7e-17 61.6 0.8 1.1e-12 48.1 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin V-set domain I-set PF07679.16 KFR01928.1 - 6.8e-16 58.1 0.1 1.4e-06 28.3 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFR01928.1 - 2.1e-15 56.7 0.0 1.8e-06 28.0 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 KFR01928.1 - 7.6e-14 52.1 3.1 1.6e-07 31.8 0.1 3.3 3 1 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KFR01928.1 - 1.4e-10 41.4 0.8 3.5e-07 30.5 0.2 2.9 2 1 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 KFR01928.1 - 0.00011 21.6 0.1 0.023 14.3 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain TMEM51 PF15345.6 KFR01928.1 - 0.026 14.4 1.8 0.063 13.1 1.4 1.7 1 1 0 1 1 1 0 Transmembrane protein 51 OSTbeta PF15048.6 KFR01928.1 - 0.029 14.5 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Miga PF10265.9 KFR01928.1 - 0.031 13.3 1.1 0.048 12.6 1.1 1.3 1 0 0 1 1 1 0 Mitoguardin FAM176 PF14851.6 KFR01928.1 - 0.032 13.9 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 FAM176 family Ig_C17orf99 PF17736.1 KFR01928.1 - 0.037 14.1 0.2 1.2 9.2 0.1 2.6 2 1 0 2 2 2 0 C17orf99 Ig domain SMN PF06003.12 KFR01928.1 - 0.13 11.5 2.0 0.23 10.7 2.0 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Trp_oprn_chp PF09534.10 KFR01928.1 - 0.14 12.0 0.1 0.27 11.0 0.1 1.5 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Ig_4 PF16680.5 KFR01928.1 - 0.15 12.4 0.3 1.1 9.5 0.2 2.5 2 1 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain EphA2_TM PF14575.6 KFR01928.1 - 0.15 13.0 0.0 0.32 11.9 0.0 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 KFR01928.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Herpes_pp85 PF04637.12 KFR01928.1 - 1.1 7.5 2.9 1.6 7.1 2.9 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF3446 PF11928.8 KFR01928.1 - 7.9 6.9 13.1 21 5.5 13.1 1.7 1 0 0 1 1 1 0 Early growth response N-terminal domain VASt PF16016.5 KFR01929.1 - 2.1e-37 128.9 2.0 3.3e-37 128.3 2.0 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KFR01929.1 - 2.2e-28 98.4 0.1 4e-28 97.6 0.1 1.5 1 0 0 1 1 1 1 GRAM domain V-set PF07686.17 KFR01930.1 - 9.4e-20 70.8 0.0 1.2e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFR01930.1 - 0.00046 20.2 0.1 0.001 19.1 0.1 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR01930.1 - 0.00054 20.5 0.2 0.0013 19.3 0.2 1.6 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFR01930.1 - 0.00058 20.0 0.3 0.0015 18.6 0.3 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFR01930.1 - 0.00093 19.5 0.3 0.003 17.9 0.3 1.9 1 1 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 KFR01930.1 - 0.03 13.9 0.0 0.083 12.5 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin domain Ac76 PF05814.11 KFR01930.1 - 0.055 13.5 0.2 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 Orf76 (Ac76) EII-GUT PF03608.13 KFR01930.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 PTS system enzyme II sorbitol-specific factor E1-E2_ATPase PF00122.20 KFR01931.1 - 5.4e-44 149.9 1.0 5.4e-44 149.9 1.0 3.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFR01931.1 - 1.2e-42 145.7 2.2 1.2e-42 145.7 2.2 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KFR01931.1 - 4.2e-26 90.9 0.0 8.8e-26 89.8 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFR01931.1 - 4.7e-20 72.8 0.0 1.1e-10 42.2 0.0 2.7 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFR01931.1 - 1.1e-15 57.1 0.0 2.3e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFR01931.1 - 1.1e-06 28.6 2.1 0.0004 20.2 1.2 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFR01931.1 - 0.023 15.1 0.1 0.16 12.3 0.1 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Sigma70_r4 PF04545.16 KFR01931.1 - 0.024 14.1 0.1 0.067 12.7 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 Glyco_transf_43 PF03360.16 KFR01932.1 - 3.8e-75 252.2 0.0 4.4e-75 252.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 Acyl-CoA_dh_1 PF00441.24 KFR01933.1 - 1.3e-45 155.3 5.6 1.8e-45 154.8 5.6 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFR01933.1 - 2e-30 105.8 0.0 4.7e-30 104.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFR01933.1 - 1.5e-25 89.2 0.0 3e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFR01933.1 - 1.8e-21 76.8 3.4 2.8e-21 76.2 3.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AcylCoA_dehyd_C PF12186.8 KFR01933.1 - 0.038 14.1 0.1 0.084 13.0 0.1 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal EVE PF01878.18 KFR01934.1 - 3.6e-50 169.7 0.0 3.6e-50 169.7 0.0 1.5 2 0 0 2 2 2 1 EVE domain Vps26 PF03643.15 KFR01935.1 - 2.8e-130 433.3 5.4 3.3e-130 433.0 5.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KFR01935.1 - 0.00011 22.3 0.7 0.083 12.9 0.0 3.1 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KFR01935.1 - 0.0011 19.4 0.3 0.04 14.4 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Ig_3 PF13927.6 KFR01936.1 - 7.2e-23 81.0 4.6 2.5e-13 50.4 1.3 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFR01936.1 - 1.9e-20 72.7 0.8 8.2e-11 41.8 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 KFR01936.1 - 3e-14 53.1 2.6 2.2e-08 34.3 0.1 2.9 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 KFR01936.1 - 1.2e-13 51.2 5.4 1.4e-09 38.2 1.5 2.7 1 1 1 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFR01936.1 - 4.8e-13 49.1 2.5 3.1e-06 27.2 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFR01936.1 - 7.4e-06 25.9 0.1 0.0012 18.8 0.0 2.8 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 KFR01936.1 - 5.5e-05 23.2 0.7 0.0059 16.7 0.1 2.3 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFR01936.1 - 0.00013 22.2 1.5 0.13 12.7 0.2 2.5 2 0 0 2 2 2 2 Immunoglobulin C1-set domain Adeno_E3_CR2 PF02439.15 KFR01936.1 - 0.17 11.7 4.6 0.31 10.8 4.6 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Ig_3 PF13927.6 KFR01937.1 - 2.4e-62 207.5 0.0 6.9e-16 58.6 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 KFR01937.1 - 2.1e-54 181.5 0.0 3.7e-15 55.8 0.0 5.7 6 0 0 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.6 KFR01937.1 - 1.2e-39 134.5 0.0 1.1e-09 38.4 0.0 5.3 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 KFR01937.1 - 2.6e-36 123.6 0.0 1.3e-11 44.5 0.0 6.1 5 1 0 5 5 5 5 Immunoglobulin domain V-set PF07686.17 KFR01937.1 - 3.3e-27 94.8 0.1 1.1e-08 35.2 0.0 7.0 4 2 2 6 6 6 5 Immunoglobulin V-set domain fn3 PF00041.21 KFR01937.1 - 3.8e-14 52.8 0.0 9e-06 25.9 0.0 3.0 3 0 0 3 3 2 2 Fibronectin type III domain Ig_6 PF18452.1 KFR01937.1 - 1.6e-09 37.1 0.0 0.33 10.6 0.0 5.3 5 0 0 5 5 5 2 Immunoglobulin domain Ig_4 PF16680.5 KFR01937.1 - 9.6e-09 35.4 0.0 0.0089 16.3 0.0 5.1 5 0 0 5 5 5 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFR01937.1 - 4.7e-06 26.6 0.0 5.6 7.1 0.0 4.3 4 0 0 4 4 4 2 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFR01937.1 - 1.8e-05 25.0 0.0 0.23 11.9 0.0 5.0 5 0 0 5 5 5 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KFR01937.1 - 4.2e-05 23.5 0.5 0.088 12.9 0.0 4.5 5 0 0 5 5 5 1 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 KFR01937.1 - 0.0014 18.7 0.0 1 9.5 0.0 4.6 4 2 0 4 4 4 1 C17orf99 Ig domain Pur_ac_phosph_N PF16656.5 KFR01937.1 - 0.0032 18.0 0.4 0.69 10.5 0.9 3.3 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Tissue_fac PF01108.17 KFR01937.1 - 0.022 14.6 0.1 0.2 11.5 0.1 2.4 2 0 0 2 2 2 0 Tissue factor V-set_CD47 PF08204.11 KFR01937.1 - 0.046 13.7 0.0 26 4.8 0.0 3.9 4 0 0 4 4 4 0 CD47 immunoglobulin-like domain Ldr_toxin PF13940.6 KFR01937.1 - 0.055 13.5 2.9 4.7 7.4 0.3 3.2 2 1 1 3 3 2 0 Toxin Ldr, type I toxin-antitoxin system DUF2369 PF10179.9 KFR01937.1 - 0.12 12.8 0.0 5.6 7.4 0.0 3.3 4 0 0 4 4 4 0 Uncharacterised conserved protein (DUF2369) Ig_3 PF13927.6 KFR01938.1 - 6.7e-37 125.9 2.3 5.7e-15 55.7 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFR01938.1 - 1.4e-36 124.4 2.5 7.4e-15 54.8 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 KFR01938.1 - 6.8e-28 96.7 4.5 8.6e-14 51.5 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFR01938.1 - 2.3e-27 95.2 2.1 9.5e-11 41.9 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFR01938.1 - 3.4e-14 52.9 7.1 5.9e-05 23.2 0.1 5.1 3 2 1 4 4 4 3 Immunoglobulin V-set domain Izumo-Ig PF16706.5 KFR01938.1 - 3.8e-08 33.3 0.1 0.0081 16.2 0.0 3.5 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFR01938.1 - 7e-08 32.8 0.0 0.24 11.9 0.0 3.4 3 1 0 3 3 3 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFR01938.1 - 8e-05 22.1 0.0 1.2 8.8 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain Ig_4 PF16680.5 KFR01938.1 - 0.00014 22.0 0.1 0.65 10.3 0.0 3.7 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain V-set_CD47 PF08204.11 KFR01938.1 - 0.00023 21.1 0.7 0.41 10.6 0.1 3.1 3 0 0 3 3 3 2 CD47 immunoglobulin-like domain C2-set_2 PF08205.12 KFR01938.1 - 0.014 15.4 0.1 0.95 9.6 0.0 2.6 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain I-set PF07679.16 KFR01939.1 - 6.3e-36 122.3 0.6 6.8e-14 51.7 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR01939.1 - 8.2e-36 122.5 0.8 2.1e-14 53.8 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFR01939.1 - 2.4e-29 101.3 0.7 1.5e-14 53.9 0.0 4.1 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFR01939.1 - 1.3e-28 99.2 1.0 2.9e-13 49.9 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFR01939.1 - 4.9e-15 55.6 3.3 0.00013 22.1 0.1 5.1 3 2 1 4 4 4 4 Immunoglobulin V-set domain Ig_5 PF16681.5 KFR01939.1 - 8.7e-10 38.9 0.2 0.0069 16.8 0.0 3.6 3 1 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFR01939.1 - 4.6e-07 29.8 0.1 0.011 15.7 0.0 3.3 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFR01939.1 - 4.6e-06 26.1 0.0 0.57 9.8 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain Ig_4 PF16680.5 KFR01939.1 - 2.6e-05 24.4 0.1 0.26 11.6 0.0 3.6 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFR01939.1 - 3.2e-05 23.9 0.1 0.053 13.6 0.1 2.6 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.11 KFR01939.1 - 0.002 18.1 0.1 1.2 9.1 0.0 3.0 3 0 0 3 3 3 1 CD47 immunoglobulin-like domain Ig_C17orf99 PF17736.1 KFR01939.1 - 0.021 14.9 0.1 0.6 10.2 0.0 3.0 2 1 0 2 2 2 0 C17orf99 Ig domain C2-set PF05790.15 KFR01939.1 - 0.045 14.0 0.2 83 3.5 0.0 4.2 3 2 1 4 4 4 0 Immunoglobulin C2-set domain PXA PF02194.15 KFR01940.1 - 8.5e-30 104.1 0.0 3.4e-29 102.1 0.0 2.1 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 KFR01940.1 - 2.7e-22 79.5 0.7 1.1e-21 77.5 0.3 2.3 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 KFR01940.1 - 6.5e-19 68.0 0.1 1.3e-18 67.0 0.1 1.5 1 0 0 1 1 1 1 PX domain TssC PF17541.2 KFR01940.1 - 0.054 12.3 0.1 0.08 11.8 0.1 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB ADAM_spacer1 PF05986.14 KFR01941.1 - 3.1e-32 111.0 0.0 4.6e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 ADAM_CR_2 PF17771.1 KFR01941.1 - 1.9e-20 73.2 14.8 1.4e-18 67.1 8.0 4.8 5 0 0 5 5 5 2 ADAM cysteine-rich domain Reprolysin PF01421.19 KFR01941.1 - 1.7e-18 67.3 0.0 1.7e-18 67.3 0.0 1.9 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease TSP_1 PF00090.19 KFR01941.1 - 6.7e-15 55.0 39.7 5.2e-08 33.0 3.2 5.8 6 0 0 6 6 6 3 Thrombospondin type 1 domain Reprolysin_5 PF13688.6 KFR01941.1 - 1.6e-12 48.0 0.0 2.4e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFR01941.1 - 2.7e-08 34.4 0.0 4.1e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFR01941.1 - 0.0015 18.4 0.0 0.0031 17.4 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFR01941.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like ADAM_spacer1 PF05986.14 KFR01942.1 - 1.6e-31 108.7 0.0 2.3e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 ADAM-TS Spacer 1 ADAM_CR_2 PF17771.1 KFR01942.1 - 3.9e-21 75.3 36.4 1.3e-20 73.7 7.1 5.3 4 1 0 4 4 4 2 ADAM cysteine-rich domain Reprolysin PF01421.19 KFR01942.1 - 6.6e-19 68.6 0.0 9.9e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease TSP_1 PF00090.19 KFR01942.1 - 3.4e-15 56.0 72.7 5.1e-06 26.6 7.1 7.2 7 0 0 7 7 7 4 Thrombospondin type 1 domain Reprolysin_3 PF13582.6 KFR01942.1 - 2.7e-12 47.3 0.0 5e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFR01942.1 - 5.8e-10 39.7 0.1 1.2e-09 38.6 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KFR01942.1 - 7.6e-06 26.0 0.0 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFR01942.1 - 0.00024 20.8 0.0 0.00041 20.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like BTB PF00651.31 KFR01943.1 - 2.1e-29 102.0 0.6 3.6e-29 101.2 0.6 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 KFR01943.1 - 4.7e-19 67.7 24.4 0.00014 22.1 0.4 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR01943.1 - 4.1e-15 55.2 18.1 0.0022 18.7 0.4 4.9 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFR01943.1 - 3.9e-13 49.2 23.1 2.8e-06 27.5 0.3 5.0 5 0 0 5 5 5 4 Zinc-finger double domain zf-met PF12874.7 KFR01943.1 - 2.2e-10 40.5 19.4 0.013 15.8 0.3 5.6 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFR01943.1 - 1.1e-08 34.9 24.1 0.0055 16.7 0.1 4.9 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFR01943.1 - 1.3e-07 31.2 20.3 0.012 15.4 0.3 4.8 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFR01943.1 - 2.9e-06 27.4 9.5 0.025 14.9 0.0 4.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFR01943.1 - 0.00014 22.1 13.0 0.3 11.4 2.4 4.1 1 1 3 4 4 4 2 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 KFR01943.1 - 0.0013 18.8 9.7 5.7 7.1 3.0 4.0 2 1 2 4 4 4 2 Zinc ribbon domain zf-C2H2_3rep PF18868.1 KFR01943.1 - 0.011 16.3 6.9 0.36 11.5 0.4 3.8 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_9 PF16293.5 KFR01943.1 - 0.023 14.5 3.3 0.16 11.8 0.1 3.2 3 0 0 3 3 2 0 C2H2 type zinc-finger (1 copy) zf-C2HE PF16278.5 KFR01943.1 - 0.027 14.9 13.7 0.21 12.1 0.0 4.9 3 1 2 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger Glyco_tran_10_N PF17039.5 KFR01943.1 - 0.05 14.1 0.2 0.2 12.1 0.2 2.0 1 0 0 1 1 1 0 Fucosyltransferase, N-terminal zf-H2C2_5 PF13909.6 KFR01943.1 - 0.097 12.5 0.1 0.097 12.5 0.1 3.0 3 0 0 3 3 2 0 C2H2-type zinc-finger domain Zn_Tnp_IS1595 PF12760.7 KFR01943.1 - 0.61 10.1 20.3 0.18 11.8 3.6 3.2 1 1 2 3 3 3 0 Transposase zinc-ribbon domain FYVE PF01363.21 KFR01943.1 - 0.81 9.9 14.5 4.1 7.6 4.5 4.1 1 1 1 2 2 2 0 FYVE zinc finger CpXC PF14353.6 KFR01943.1 - 1 9.4 9.2 43 4.2 6.4 3.6 1 1 2 3 3 3 0 CpXC protein zf-AN1 PF01428.16 KFR01943.1 - 2.2 8.5 12.3 6.1 7.1 0.1 4.5 4 0 0 4 4 4 0 AN1-like Zinc finger C1_1 PF00130.22 KFR01943.1 - 3.1 7.8 9.6 1 9.3 3.8 2.8 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf_UBZ PF18439.1 KFR01943.1 - 3.4 7.3 11.0 2.2 7.9 0.1 4.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger LIM PF00412.22 KFR01943.1 - 4.6 7.5 12.5 3.1 8.1 6.2 3.5 3 1 0 3 3 3 0 LIM domain Trypsin PF00089.26 KFR01944.1 - 3.4e-66 223.2 1.2 4.9e-66 222.7 0.2 1.7 2 0 0 2 2 2 1 Trypsin CUB PF00431.20 KFR01944.1 - 1.8e-36 124.8 0.4 3.8e-19 69.0 0.4 2.6 2 0 0 2 2 2 2 CUB domain Ldl_recept_a PF00057.18 KFR01944.1 - 1.4e-34 118.0 82.0 1.3e-09 38.1 9.7 5.0 5 0 0 5 5 5 4 Low-density lipoprotein receptor domain class A SEA PF01390.20 KFR01944.1 - 1.6e-12 47.5 0.1 1e-11 44.8 0.0 2.1 2 0 0 2 2 2 1 SEA domain DUF1986 PF09342.11 KFR01944.1 - 6.9e-06 26.4 0.0 2e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) CUB_2 PF02408.20 KFR01944.1 - 8.1e-05 22.4 2.0 0.00033 20.4 0.7 2.4 2 0 0 2 2 2 1 CUB-like domain NFRKB_winged PF14465.6 KFR01945.1 - 6.9e-32 109.7 3.1 8e-32 109.5 1.0 2.3 2 0 0 2 2 2 1 NFRKB Winged Helix-like Apt1 PF10351.9 KFR01945.1 - 0.026 13.4 0.4 0.059 12.2 0.4 1.6 1 0 0 1 1 1 0 Golgi-body localisation protein domain ATP-synt_E PF05680.12 KFR01945.1 - 3.3 8.1 8.1 1.2 9.6 2.3 2.8 2 0 0 2 2 2 0 ATP synthase E chain Tristanin_u2 PF16638.5 KFR01946.1 - 6e-50 169.4 6.4 6e-50 169.4 6.4 4.1 4 1 0 4 4 2 1 Unstructured region on methyltransferase between zinc-fingers zf-C2H2 PF00096.26 KFR01946.1 - 7.3e-33 111.2 77.2 5.6e-05 23.4 2.5 10.8 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR01946.1 - 7e-27 91.8 79.8 0.0047 17.7 1.7 11.0 11 0 0 11 11 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFR01946.1 - 4.6e-18 64.7 66.4 0.00048 20.4 0.4 12.2 11 1 0 11 11 11 7 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFR01946.1 - 3.6e-15 55.8 56.8 0.0024 18.1 0.0 10.7 11 0 0 11 11 11 7 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFR01946.1 - 7.8e-09 35.8 46.1 0.17 12.3 11.0 9.6 5 2 4 9 9 9 5 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 KFR01946.1 - 4.8e-07 30.5 22.8 2.2 9.0 1.0 7.8 5 1 2 7 7 7 4 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 KFR01946.1 - 4.9e-07 29.6 49.3 0.0033 17.4 0.4 9.0 8 0 0 8 8 8 4 C2H2-type zinc finger zf-met PF12874.7 KFR01946.1 - 8.1e-06 26.0 2.6 0.0032 17.8 0.0 9.4 9 0 0 9 9 8 3 Zinc-finger of C2H2 type zf_PR_Knuckle PF18445.1 KFR01946.1 - 8.5e-06 25.5 2.0 8.5e-06 25.5 2.0 3.9 4 0 0 4 4 3 1 PR zinc knuckle motif zf-Di19 PF05605.12 KFR01946.1 - 0.0045 17.2 44.2 0.086 13.2 2.6 7.6 6 1 1 8 8 8 4 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 KFR01946.1 - 0.01 15.4 40.3 1.1 8.9 0.1 8.9 9 0 0 9 9 9 0 Ubiquitin-Binding Zinc Finger zf-BED PF02892.15 KFR01946.1 - 0.015 15.3 3.0 0.015 15.3 3.0 7.5 6 2 1 7 7 7 0 BED zinc finger zf_C2H2_ZHX PF18387.1 KFR01946.1 - 0.47 10.1 0.0 0.47 10.1 0.0 7.9 8 1 1 9 9 9 0 Zinc-fingers and homeoboxes C2H2 finger domain Zn_Tnp_IS1595 PF12760.7 KFR01946.1 - 0.63 10.1 25.9 0.047 13.7 1.4 5.7 5 0 0 5 5 5 0 Transposase zinc-ribbon domain DUF629 PF04780.12 KFR01946.1 - 0.73 8.3 44.4 0.28 9.7 0.0 7.5 5 2 2 8 8 8 0 Protein of unknown function (DUF629) Zn-C2H2_12 PF18112.1 KFR01946.1 - 6.3 7.4 19.3 2.9 8.4 0.3 5.4 5 0 0 5 5 5 0 Autophagy receptor zinc finger-C2H2 domain DUF4428 PF14471.6 KFR01946.1 - 7.1 6.6 12.3 0.85 9.6 0.0 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4428) APP_E2 PF12925.7 KFR01947.1 - 1.5e-69 233.6 17.4 3.2e-69 232.4 17.4 1.6 1 0 0 1 1 1 1 E2 domain of amyloid precursor protein APP_N PF02177.16 KFR01947.1 - 1e-42 144.5 1.0 1e-42 144.5 1.0 2.5 3 0 0 3 3 3 1 Amyloid A4 N-terminal heparin-binding APP_Cu_bd PF12924.7 KFR01947.1 - 7e-27 93.9 5.5 7e-27 93.9 5.5 3.5 3 0 0 3 3 3 1 Copper-binding of amyloid precursor, CuBD APP_amyloid PF10515.9 KFR01947.1 - 8e-26 90.3 0.2 4.2e-25 88.0 0.2 2.4 1 0 0 1 1 1 1 Beta-amyloid precursor protein C-terminus Kunitz_BPTI PF00014.23 KFR01947.1 - 7.9e-20 70.8 5.1 7.9e-20 70.8 5.1 2.3 3 0 0 3 3 3 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Insulin_TMD PF17870.1 KFR01947.1 - 0.45 10.6 1.4 0.99 9.5 1.4 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment FNIP_M PF14637.6 KFR01947.1 - 0.96 9.4 3.8 13 5.7 0.4 2.4 2 0 0 2 2 2 0 Folliculin-interacting protein middle domain Activator-TraM PF11657.8 KFR01947.1 - 1.4 8.8 5.9 3.1 7.7 5.9 1.5 1 0 0 1 1 1 0 Transcriptional activator TraM DUF5480 PF17576.2 KFR01947.1 - 8 6.5 5.9 20 5.2 5.9 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5480) DUF716 PF04819.12 KFR01949.1 - 1.7e-26 92.5 4.7 1.7e-26 92.5 4.7 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF716) ASFV_L11L PF05293.11 KFR01949.1 - 1.4 9.3 4.7 14 6.1 0.4 2.5 1 1 1 2 2 2 0 African swine fever virus (ASFV) L11L protein DUF716 PF04819.12 KFR01950.1 - 2.3e-29 101.8 9.6 4e-29 101.0 9.6 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF716) TnpB_IS66 PF05717.13 KFR01950.1 - 0.055 13.4 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 IS66 Orf2 like protein Homeodomain PF00046.29 KFR01951.1 - 2.8e-21 75.1 3.4 2.8e-21 75.1 3.4 1.9 2 0 0 2 2 2 1 Homeodomain Homez PF11569.8 KFR01951.1 - 0.19 11.2 1.2 0.37 10.3 1.2 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez RhoGAP PF00620.27 KFR01952.1 - 2.6e-37 128.0 0.0 4.6e-37 127.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PX PF00787.24 KFR01952.1 - 0.00018 21.5 0.1 0.001 19.1 0.0 2.3 2 0 0 2 2 2 1 PX domain RPEL PF02755.15 KFR01952.1 - 0.015 15.0 0.1 0.032 13.9 0.1 1.6 1 0 0 1 1 1 0 RPEL repeat IRK_C PF17655.1 KFR01953.1 - 8.4e-75 250.2 0.1 1.1e-74 249.8 0.1 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFR01953.1 - 8.4e-58 194.2 2.6 1.2e-57 193.7 2.6 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 KFR01953.1 - 0.02 14.9 8.9 0.061 13.3 8.9 1.8 1 1 0 1 1 1 0 Ion channel Ion_trans PF00520.31 KFR01953.1 - 0.039 13.2 3.1 0.057 12.6 3.1 1.2 1 0 0 1 1 1 0 Ion transport protein IRK_C PF17655.1 KFR01954.1 - 1.1e-65 220.5 0.0 1.4e-65 220.1 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFR01954.1 - 3.1e-59 198.8 2.4 6.8e-59 197.7 2.4 1.6 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain DUF2182 PF09948.9 KFR01954.1 - 0.042 13.7 1.7 0.072 13.0 0.1 2.0 2 1 1 3 3 3 0 Predicted metal-binding integral membrane protein (DUF2182) CrgA PF06781.12 KFR01954.1 - 0.11 12.6 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 Cell division protein CrgA Ion_trans_2 PF07885.16 KFR01954.1 - 1.4 8.9 7.6 4 7.5 7.4 1.9 1 1 0 1 1 1 0 Ion channel Ets PF00178.22 KFR01955.1 - 2.9e-36 123.8 0.4 7.2e-36 122.5 0.4 1.7 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 KFR01955.1 - 4.1e-26 90.8 0.1 1.1e-25 89.4 0.1 1.7 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Ig_3 PF13927.6 KFR01956.1 - 1.5e-46 156.8 0.7 4.2e-11 43.3 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 KFR01956.1 - 1.1e-42 143.9 0.1 8.9e-12 44.9 0.0 5.7 5 2 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.6 KFR01956.1 - 2.4e-36 123.9 0.7 4.2e-07 30.2 0.0 5.7 6 0 0 6 6 5 5 Immunoglobulin domain ig PF00047.25 KFR01956.1 - 2.3e-24 85.4 2.6 5.6e-05 23.2 1.1 5.9 5 1 0 5 5 5 4 Immunoglobulin domain C2-set_2 PF08205.12 KFR01956.1 - 7.6e-13 48.3 0.1 4.3e-07 29.9 0.0 4.4 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFR01956.1 - 4.4e-12 46.1 1.0 0.49 10.6 0.0 7.3 5 3 1 6 6 6 3 Immunoglobulin V-set domain C1-set PF07654.15 KFR01956.1 - 4.3e-06 27.0 0.0 0.0047 17.3 0.0 4.4 4 1 0 4 4 4 1 Immunoglobulin C1-set domain Ig_4 PF16680.5 KFR01956.1 - 2e-05 24.7 0.0 0.014 15.6 0.0 4.4 5 0 0 5 5 5 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFR01956.1 - 3.3e-05 24.2 0.0 1.2 9.6 0.0 5.1 5 0 0 5 5 5 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Mid2 PF04478.12 KFR01956.1 - 0.031 14.1 0.2 0.093 12.6 0.1 1.8 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Izumo-Ig PF16706.5 KFR01956.1 - 0.058 13.5 0.0 0.23 11.5 0.0 2.0 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFR01956.1 - 0.13 11.9 0.0 0.36 10.4 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin domain Glyco_transf_29 PF00777.18 KFR01958.1 - 1.4e-64 218.1 0.0 1.7e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) DcpS_C PF11969.8 KFR01959.1 - 3.5e-31 108.0 0.6 1.2e-30 106.4 0.0 1.9 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 KFR01959.1 - 4.8e-14 53.1 0.1 9.8e-14 52.1 0.1 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal CENP-B_N PF04218.13 KFR01959.1 - 0.062 12.9 0.0 0.24 11.1 0.0 1.9 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HIT PF01230.23 KFR01959.1 - 0.14 12.9 0.6 0.57 10.9 0.1 2.2 2 1 0 2 2 2 0 HIT domain TIR_2 PF13676.6 KFR01960.1 - 3.1e-19 69.7 0.0 4.3e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 KFR01960.1 - 5.6e-09 36.1 0.0 7.1e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 TIR domain FAD_binding_7 PF03441.14 KFR01961.1 - 4e-77 258.3 0.1 5.1e-77 257.9 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KFR01961.1 - 1.7e-23 83.4 0.0 3.2e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase SIR2_2 PF13289.6 KFR01962.1 - 3e-23 82.5 0.2 5.6e-23 81.6 0.1 1.5 2 0 0 2 2 2 1 SIR2-like domain RFC1 PF08519.12 KFR01962.1 - 0.15 12.2 0.1 0.47 10.6 0.1 1.8 2 0 0 2 2 2 0 Replication factor RFC1 C terminal domain SRP-alpha_N PF04086.13 KFR01963.1 - 6.7e-58 196.9 11.3 8.6e-58 196.5 11.3 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KFR01963.1 - 1.4e-48 165.2 0.4 1.2e-47 162.1 0.4 2.2 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KFR01963.1 - 3.6e-10 39.9 0.3 2.2e-09 37.4 0.1 2.4 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KFR01963.1 - 1.1e-07 31.2 0.0 1.9e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 KFR01963.1 - 0.00091 19.3 0.0 0.03 14.4 0.0 2.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 KFR01963.1 - 0.0084 15.9 0.1 0.016 14.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KFR01963.1 - 0.028 13.6 0.4 0.7 9.0 0.0 2.6 3 0 0 3 3 3 0 Anion-transporting ATPase AAA_33 PF13671.6 KFR01963.1 - 0.032 14.4 0.0 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KFR01963.1 - 0.036 14.0 0.2 0.45 10.4 0.0 2.6 2 1 0 2 2 2 0 NTPase Fer4_NifH PF00142.18 KFR01963.1 - 0.05 13.1 0.0 0.099 12.1 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_16 PF13191.6 KFR01963.1 - 0.075 13.4 0.0 0.19 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain EI24 PF07264.11 KFR01964.1 - 1.6e-20 74.1 15.4 2.5e-20 73.4 15.4 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) STT3 PF02516.14 KFR01965.1 - 1.2e-164 548.9 42.9 1.1e-159 532.5 38.3 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.6 KFR01965.1 - 1.1e-06 29.0 15.6 1.1e-06 29.0 15.6 2.6 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF2985 PF11204.8 KFR01965.1 - 0.28 11.4 7.0 0.36 11.0 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2985) Pkinase PF00069.25 KFR01966.1 - 0.095 12.0 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Ig_3 PF13927.6 KFR01967.1 - 2.3e-65 217.2 0.4 8.6e-18 64.7 0.1 5.8 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 KFR01967.1 - 7.7e-60 199.0 0.0 3.7e-14 52.6 0.0 6.3 6 1 0 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.6 KFR01967.1 - 1.9e-47 159.5 0.0 7.9e-10 38.9 0.0 6.0 4 2 1 5 5 5 5 Immunoglobulin domain ig PF00047.25 KFR01967.1 - 1.3e-40 137.5 0.0 8.7e-08 32.2 0.0 6.1 5 1 0 5 5 5 5 Immunoglobulin domain fn3 PF00041.21 KFR01967.1 - 2.2e-37 127.3 5.6 1.7e-16 60.3 0.1 4.1 4 0 0 4 4 4 3 Fibronectin type III domain V-set PF07686.17 KFR01967.1 - 2e-23 82.6 8.3 7.7e-06 26.0 0.0 9.3 8 3 3 11 11 9 4 Immunoglobulin V-set domain Ig_6 PF18452.1 KFR01967.1 - 6.5e-12 44.8 0.0 0.041 13.5 0.0 5.5 5 0 0 5 5 5 2 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFR01967.1 - 1.2e-08 35.4 0.4 0.0073 16.9 0.0 3.7 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Izumo-Ig PF16706.5 KFR01967.1 - 5.9e-05 23.0 0.0 15 5.7 0.0 5.4 6 0 0 6 6 6 0 Izumo-like Immunoglobulin domain BiPBP_C PF06832.12 KFR01967.1 - 0.0041 17.1 0.0 0.43 10.7 0.0 3.6 4 0 0 4 4 4 1 Penicillin-Binding Protein C-terminus Family Tissue_fac PF01108.17 KFR01967.1 - 0.01 15.6 0.1 0.36 10.7 0.0 3.0 3 0 0 3 3 3 0 Tissue factor UL141 PF16758.5 KFR01967.1 - 0.03 14.0 0.1 5.3 6.7 0.0 3.5 4 0 0 4 4 4 0 Herpes-like virus membrane glycoprotein UL141 Herpes_gE PF02480.16 KFR01967.1 - 0.043 12.6 0.0 8.2 5.0 0.0 3.3 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 KFR01967.1 - 0.091 13.7 0.0 0.2 12.6 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Interfer-bind PF09294.10 KFR01967.1 - 0.15 12.3 0.1 1.5 9.2 0.2 2.3 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III V-set_CD47 PF08204.11 KFR01967.1 - 0.18 11.8 0.0 6.1 6.8 0.0 2.9 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain TNFR_16_TM PF18422.1 KFR01967.1 - 0.2 11.6 2.1 0.43 10.6 2.1 1.4 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Fer4_2 PF12797.7 KFR01967.1 - 0.74 10.0 3.7 1.7 8.9 3.7 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain DEAD PF00270.29 KFR01968.1 - 5.3e-28 98.0 0.0 8.3e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFR01968.1 - 4.3e-26 91.4 0.1 8.7e-26 90.4 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFR01968.1 - 0.00041 20.4 0.0 0.0007 19.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KFR01968.1 - 0.02 14.6 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain HYLS1_C PF15311.6 KFR01969.1 - 8.2e-24 84.2 1.4 9.1e-24 84.0 1.4 1.0 1 0 0 1 1 1 1 Hydrolethalus syndrome protein 1 C-terminus PseudoU_synth_1 PF01416.20 KFR01970.1 - 1.6e-32 112.2 0.0 9.1e-31 106.5 0.0 2.4 2 0 0 2 2 2 1 tRNA pseudouridine synthase GHMP_kinases_C PF08544.13 KFR01970.1 - 0.039 14.3 0.1 0.38 11.2 0.0 2.4 2 0 0 2 2 2 0 GHMP kinases C terminal Tropomyosin_1 PF12718.7 KFR01970.1 - 0.05 13.8 1.1 0.1 12.8 1.1 1.4 1 0 0 1 1 1 0 Tropomyosin like WD40_alt PF14077.6 KFR01970.1 - 0.077 12.9 1.0 0.21 11.5 1.0 1.8 1 0 0 1 1 1 0 Alternative WD40 repeat motif BST2 PF16716.5 KFR01970.1 - 0.23 12.1 1.5 0.69 10.5 0.3 2.2 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 PseudoU_synth_2 PF00849.22 KFR01971.1 - 8.2e-35 120.2 0.0 1.2e-34 119.7 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Innexin PF00876.18 KFR01972.1 - 7.9e-13 48.4 1.2 3.2e-12 46.4 1.2 1.7 1 1 0 1 1 1 1 Innexin Sensor PF13796.6 KFR01972.1 - 3.1 7.8 10.3 44 4.1 10.3 2.8 1 1 0 1 1 1 0 Putative sensor IQ PF00612.27 KFR01973.1 - 7.1e-06 25.4 0.4 1.4e-05 24.5 0.4 1.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif Ig_3 PF13927.6 KFR01974.1 - 6.8e-14 52.2 0.1 8.5e-10 39.1 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFR01974.1 - 1.2e-11 44.6 0.1 6.5e-05 23.0 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFR01974.1 - 5.7e-11 42.3 0.0 4e-07 30.0 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFR01974.1 - 1.3e-09 38.3 0.1 4.1e-06 27.0 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFR01974.1 - 3e-08 33.8 0.5 0.012 15.7 0.0 3.0 2 1 1 3 3 3 2 Immunoglobulin V-set domain Ig_6 PF18452.1 KFR01974.1 - 7.9e-06 25.4 0.0 0.01 15.4 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_5 PF16681.5 KFR01974.1 - 0.0067 16.8 0.0 0.14 12.5 0.0 2.2 2 0 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KFR01974.1 - 0.031 14.4 0.1 0.075 13.1 0.0 1.7 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFR01974.1 - 0.037 14.3 0.0 3.4 8.0 0.0 2.7 2 1 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain Receptor_2B4 PF11465.8 KFR01974.1 - 0.08 13.2 0.0 0.25 11.6 0.0 1.8 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 zf-H2C2_2 PF13465.6 KFR01984.1 - 1.9e-81 265.1 93.8 3.8e-10 39.7 2.7 13.8 14 0 0 14 14 14 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFR01984.1 - 5e-80 259.7 100.4 2.6e-08 33.9 2.1 12.9 13 0 0 13 13 13 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR01984.1 - 4.3e-46 151.6 94.6 2e-05 25.0 0.9 12.5 13 0 0 13 13 12 12 C2H2-type zinc finger zf_UBZ PF18439.1 KFR01984.1 - 4.1e-20 71.1 43.1 0.15 11.6 0.0 12.1 12 0 0 12 12 12 8 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 KFR01984.1 - 1.1e-18 67.1 30.9 0.0091 16.3 0.1 11.1 12 0 0 12 12 12 4 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KFR01984.1 - 2.4e-18 66.0 49.8 4.9e-05 23.3 0.9 8.3 7 2 0 7 7 7 5 Zinc ribbon domain zf-C2H2_6 PF13912.6 KFR01984.1 - 1.8e-15 56.5 82.2 1.7e-05 24.7 1.4 12.8 12 1 0 12 12 12 6 C2H2-type zinc finger zf-Di19 PF05605.12 KFR01984.1 - 1.3e-10 41.4 53.8 0.00012 22.3 2.1 7.7 5 2 3 8 8 8 5 Drought induced 19 protein (Di19), zinc-binding FYDLN_acid PF09538.10 KFR01984.1 - 1.2e-08 35.6 37.4 1.7 9.4 0.1 10.9 1 1 9 11 11 11 2 Protein of unknown function (FYDLN_acid) DZR PF12773.7 KFR01984.1 - 3.5e-08 33.3 52.9 1.8e+04 -29.3 52.9 7.3 1 1 0 1 1 0 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 KFR01984.1 - 7.7e-08 33.0 35.0 0.1 13.4 0.2 5.8 2 1 3 6 6 6 5 zinc-ribbon family C1_4 PF07975.12 KFR01984.1 - 1.3e-07 31.8 47.2 0.0063 16.7 0.3 9.5 2 2 6 9 9 9 3 TFIIH C1-like domain XPA_N PF01286.18 KFR01984.1 - 1.9e-06 27.8 53.7 0.14 12.2 0.1 11.7 12 0 0 12 12 12 2 XPA protein N-terminal CpXC PF14353.6 KFR01984.1 - 4.1e-06 26.8 46.5 0.61 10.2 5.8 10.4 4 3 3 9 9 9 3 CpXC protein HypA PF01155.19 KFR01984.1 - 1.6e-05 24.9 37.1 0.67 10.0 2.3 6.4 1 1 4 5 5 5 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ADK_lid PF05191.14 KFR01984.1 - 2e-05 24.5 49.6 0.03 14.3 0.6 8.8 6 2 4 10 10 10 4 Adenylate kinase, active site lid zf-LYAR PF08790.11 KFR01984.1 - 2.4e-05 24.1 51.2 0.59 10.1 0.2 10.8 11 0 0 11 11 10 3 LYAR-type C2HC zinc finger DUF3268 PF11672.8 KFR01984.1 - 2.7e-05 24.5 34.7 0.023 15.0 0.2 6.3 3 1 0 6 6 6 2 zinc-finger-containing domain zinc_ribbon_9 PF14369.6 KFR01984.1 - 0.00011 22.4 50.9 2.9 8.2 0.3 11.3 12 0 0 12 12 12 3 zinc-ribbon zf-C2HC_2 PF13913.6 KFR01984.1 - 0.00014 21.7 64.8 0.0032 17.3 0.9 11.5 12 0 0 12 12 11 3 zinc-finger of a C2HC-type zf-trcl PF13451.6 KFR01984.1 - 0.0012 18.7 48.0 0.77 9.7 1.6 11.0 9 3 0 9 9 9 2 Probable zinc-ribbon domain Zn_ribbon_SprT PF17283.2 KFR01984.1 - 0.0013 18.6 68.8 0.48 10.4 7.5 10.2 6 4 3 9 9 9 3 SprT-like zinc ribbon domain YacG PF03884.14 KFR01984.1 - 0.021 14.5 34.2 8.9 6.1 0.1 9.6 10 0 0 10 10 10 0 DNA gyrase inhibitor YacG LIM PF00412.22 KFR01984.1 - 0.058 13.6 0.2 0.058 13.6 0.2 8.2 2 2 6 9 9 8 0 LIM domain BDHCT_assoc PF16204.5 KFR01984.1 - 0.063 13.0 1.2 3.1 7.4 0.1 3.3 1 1 2 3 3 3 0 BDHCT-box associated domain on Bloom syndrome protein GAGA PF09237.11 KFR01984.1 - 0.071 12.9 0.3 0.071 12.9 0.3 7.7 4 3 5 9 9 9 0 GAGA factor DNA_RNApol_7kD PF03604.13 KFR01984.1 - 0.077 12.7 48.0 1.9 8.2 0.1 11.4 11 1 0 11 11 11 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_4 PF13717.6 KFR01984.1 - 0.08 12.9 49.5 12 6.0 0.2 10.7 10 2 0 10 10 10 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 KFR01984.1 - 0.083 12.9 47.7 46 4.1 6.3 7.6 1 1 1 3 3 2 0 zinc-ribbons zf-RING_7 PF02591.15 KFR01984.1 - 0.086 13.0 39.2 6.8 7.0 0.1 9.6 10 0 0 10 10 9 0 C4-type zinc ribbon domain zf-HYPF PF07503.12 KFR01984.1 - 0.099 12.4 0.2 0.099 12.4 0.2 9.5 9 2 1 10 10 10 0 HypF finger zf-AN1 PF01428.16 KFR01984.1 - 0.11 12.6 67.2 6.1 7.1 0.2 12.1 8 3 4 12 12 12 0 AN1-like Zinc finger zf-met PF12874.7 KFR01984.1 - 0.87 10.1 52.5 1.6 9.2 0.9 9.7 10 0 0 10 10 9 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFR01984.1 - 0.97 9.2 83.6 0.8 9.5 1.2 13.4 11 2 2 13 13 13 0 zinc-finger C2H2-type YhfH PF14149.6 KFR01984.1 - 1.2 9.2 48.8 11 6.1 0.0 10.7 11 1 1 12 12 10 0 YhfH-like protein zf-C2H2_9 PF16293.5 KFR01984.1 - 2.8 7.9 29.0 11 5.9 0.1 8.0 8 1 1 9 9 9 0 C2H2 type zinc-finger (1 copy) Zn-C2H2_12 PF18112.1 KFR01984.1 - 3.6 8.1 36.8 19 5.8 0.1 8.9 9 0 0 9 9 9 0 Autophagy receptor zinc finger-C2H2 domain Zn_Tnp_IS1595 PF12760.7 KFR01984.1 - 4.4 7.4 76.9 0.055 13.5 3.1 8.0 4 3 3 8 8 8 0 Transposase zinc-ribbon domain DuoxA PF10204.9 KFR02021.1 - 5.7e-106 353.6 8.7 6.5e-106 353.4 8.7 1.0 1 0 0 1 1 1 1 Dual oxidase maturation factor Claudin_2 PF13903.6 KFR02021.1 - 0.2 11.4 15.8 0.34 10.7 6.1 2.4 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction BRI3BP PF14965.6 KFR02021.1 - 5.5 6.5 12.5 0.46 10.0 2.5 2.3 2 0 0 2 2 2 0 Negative regulator of p53/TP53 DUF4191 PF13829.6 KFR02021.1 - 6.7 6.0 14.3 1.3 8.4 3.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) DuoxA PF10204.9 KFR02022.1 - 5.2e-112 373.4 13.4 6e-112 373.2 13.4 1.0 1 0 0 1 1 1 1 Dual oxidase maturation factor Tetraspanin PF00335.20 KFR02022.1 - 8.2 6.1 14.7 0.33 10.6 0.5 3.0 2 1 1 3 3 3 0 Tetraspanin family Fijivirus_P9-2 PF06837.11 KFR02022.1 - 8.6 5.8 9.0 0.53 9.7 2.0 2.0 2 0 0 2 2 2 0 Fijivirus P9-2 protein An_peroxidase PF03098.15 KFR02023.1 - 7.6e-133 443.9 0.0 1.1e-132 443.4 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase NAD_binding_6 PF08030.12 KFR02023.1 - 2.3e-30 105.8 0.0 6.6e-30 104.3 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KFR02023.1 - 6.8e-20 71.5 17.7 2.5e-19 69.6 17.7 2.1 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFR02023.1 - 4.9e-18 65.2 0.0 1.4e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain EF-hand_1 PF00036.32 KFR02023.1 - 1.2e-14 52.7 5.4 6.1e-07 28.5 0.5 3.0 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFR02023.1 - 4.5e-11 42.4 6.1 2.5e-06 27.3 0.1 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 KFR02023.1 - 4.9e-11 42.9 6.9 9.1e-07 29.2 2.8 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFR02023.1 - 4e-10 38.8 5.5 0.00058 19.6 0.4 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KFR02023.1 - 3.4e-08 32.6 2.9 0.0029 17.0 0.3 2.8 2 0 0 2 2 2 2 EF hand NAD_binding_1 PF00175.21 KFR02023.1 - 0.00027 21.5 0.6 0.016 15.9 0.0 3.3 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain ADH_N PF08240.12 KFR02024.1 - 3.4e-24 84.8 0.1 8.5e-24 83.5 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFR02024.1 - 5.6e-22 78.1 0.4 1.1e-21 77.1 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFR02024.1 - 3.8e-09 36.3 1.4 2.4e-08 33.7 1.4 2.1 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KFR02024.1 - 3.4e-05 23.2 0.5 5.6e-05 22.5 0.5 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KFR02024.1 - 0.023 15.7 0.0 0.048 14.7 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DUF281 PF03436.13 KFR02024.1 - 0.045 14.1 0.1 0.14 12.6 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF281) DUF2249 PF10006.9 KFR02024.1 - 0.051 13.4 0.0 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) RRM_1 PF00076.22 KFR02025.1 - 7.7e-12 44.9 0.5 1.1e-11 44.3 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFR02025.1 - 0.19 11.8 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif PHM7_cyt PF14703.6 KFR02025.1 - 1.1 9.4 2.8 1.3 9.2 0.0 2.2 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter ASCH PF04266.14 KFR02028.1 - 3.4e-21 75.8 0.0 6.7e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 ASCH domain zf-C2HC5 PF06221.13 KFR02028.1 - 1.5e-10 40.9 11.2 3.2e-10 39.8 11.2 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type CK1gamma_C PF12605.8 KFR02029.1 - 4e-31 108.1 5.4 8.1e-31 107.1 5.4 1.5 1 0 0 1 1 1 1 Casein kinase 1 gamma C terminal Pkinase PF00069.25 KFR02029.1 - 1.4e-12 47.6 0.0 2.9e-12 46.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KFR02029.1 - 3.3e-05 22.8 0.1 5.2e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KFR02029.1 - 0.00037 19.9 0.0 0.0013 18.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pro_isomerase PF00160.21 KFR02030.1 - 9.6e-51 172.2 0.3 1.1e-50 172.0 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Vps5 PF09325.10 KFR02031.1 - 2e-82 276.3 21.1 2e-82 276.3 21.1 1.5 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 KFR02031.1 - 5.3e-28 97.3 1.7 1.2e-27 96.1 0.1 2.2 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.9 KFR02031.1 - 3.3e-05 23.5 2.9 0.0032 17.0 2.9 2.4 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein FUSC PF04632.12 KFR02031.1 - 0.076 11.5 6.0 0.11 11.0 6.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2833 PF11090.8 KFR02031.1 - 0.52 10.7 2.3 0.56 10.6 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2833) HR1 PF02185.16 KFR02031.1 - 0.89 9.7 7.2 1.4 9.0 1.2 3.0 2 0 0 2 2 2 0 Hr1 repeat Arfaptin PF06456.13 KFR02031.1 - 1.6 8.2 13.5 0.04 13.5 3.5 2.4 2 0 0 2 2 2 0 Arfaptin-like domain DUF2043 PF09740.9 KFR02031.1 - 3.6 8.3 7.1 2.7 8.7 3.9 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2043) PAT1 PF09770.9 KFR02032.1 - 3.3e-16 58.8 0.4 2.5e-13 49.3 0.0 2.2 2 0 0 2 2 2 2 Topoisomerase II-associated protein PAT1 C1-set PF07654.15 KFR02033.1 - 3.7e-21 75.3 0.1 4.3e-21 75.1 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.6 KFR02033.1 - 6e-06 26.8 0.0 7.6e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFR02033.1 - 0.00046 20.3 0.0 0.00064 19.8 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFR02033.1 - 0.00054 20.2 0.0 0.00074 19.8 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFR02033.1 - 0.0047 17.0 0.0 0.006 16.6 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain C2-set_2 PF08205.12 KFR02033.1 - 0.021 14.9 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain DUF1830 PF08865.11 KFR02033.1 - 0.2 11.7 0.0 21 5.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1830) TERB2 PF15101.6 KFR02034.1 - 5.8e-79 264.9 0.0 7e-79 264.7 0.0 1.0 1 0 0 1 1 1 1 Telomere-associated protein TERB2 Ribosomal_S17e PF00833.18 KFR02035.1 - 3.5e-60 201.3 0.1 4e-60 201.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 CEBP1_N PF16368.5 KFR02036.1 - 3.5e-158 526.0 16.4 4.3e-158 525.7 16.4 1.1 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein 1 N-terminus RRM_7 PF16367.5 KFR02036.1 - 1.8e-36 124.2 0.0 5.1e-36 122.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif CEBP_ZZ PF16366.5 KFR02036.1 - 1.8e-24 85.7 8.3 1.8e-24 85.7 8.3 1.6 2 0 0 2 2 2 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 KFR02036.1 - 9.5e-08 31.8 0.0 0.028 14.2 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AF-4 PF05110.13 KFR02036.1 - 6.3 4.7 7.5 9 4.2 7.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Hormone_recep PF00104.30 KFR02037.1 - 8.5e-31 107.1 0.1 3.6e-30 105.1 0.1 1.8 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFR02037.1 - 3.9e-28 97.7 14.2 4.5e-28 97.5 12.5 1.9 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Myosin_head PF00063.21 KFR02038.1 - 7.9e-215 715.1 10.9 1e-185 618.8 5.9 2.4 2 0 0 2 2 2 2 Myosin head (motor domain) RhoGAP PF00620.27 KFR02038.1 - 2e-48 164.1 0.1 2.8e-47 160.3 0.0 2.9 2 0 0 2 2 2 1 RhoGAP domain RA PF00788.23 KFR02038.1 - 3.2e-22 79.0 0.0 1.9e-21 76.5 0.0 2.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain IQ PF00612.27 KFR02038.1 - 5e-19 66.3 41.7 0.00018 21.0 0.2 7.1 6 1 1 7 7 7 5 IQ calmodulin-binding motif C1_1 PF00130.22 KFR02038.1 - 4.8e-06 26.3 12.3 9.4e-06 25.4 12.3 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) APG6_N PF17675.1 KFR02038.1 - 0.0079 16.7 1.8 0.0079 16.7 1.8 4.0 3 0 0 3 3 3 1 Apg6 coiled-coil region AAA_16 PF13191.6 KFR02038.1 - 0.02 15.3 0.2 0.24 11.8 0.0 2.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KFR02038.1 - 0.07 13.4 0.0 0.07 13.4 0.0 3.6 4 0 0 4 4 4 0 AAA domain T2SSE PF00437.20 KFR02038.1 - 0.17 11.0 2.7 0.18 10.8 0.0 2.4 3 0 0 3 3 3 0 Type II/IV secretion system protein DUF5320 PF17253.2 KFR02038.1 - 4 8.5 6.1 4.8 8.3 0.2 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Peptidase_C48 PF02902.19 KFR02039.1 - 3.4e-13 49.9 0.8 1.9e-12 47.5 0.8 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GRAM PF02893.20 KFR02040.1 - 7.4e-21 74.2 0.0 1.6e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 GRAM domain CC2D2AN-C2 PF15625.6 KFR02040.1 - 0.039 13.7 0.1 0.075 12.8 0.1 1.5 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain PK PF00224.21 KFR02041.1 - 7.8e-170 564.3 3.6 9.3e-170 564.1 3.6 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KFR02041.1 - 6.3e-35 119.9 0.0 3.3e-34 117.6 0.0 2.3 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KFR02041.1 - 0.00042 19.5 0.2 0.00094 18.4 0.2 1.7 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family RRM_1 PF00076.22 KFR02042.1 - 3.1e-32 110.2 0.0 4.2e-18 64.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 KFR02042.1 - 0.042 13.9 0.0 2.2 8.4 0.0 2.5 2 0 0 2 2 2 0 RNA binding domain RRM_7 PF16367.5 KFR02042.1 - 0.045 13.9 0.1 15 5.8 0.0 2.6 2 1 0 2 2 2 0 RNA recognition motif Peripla_BP_4 PF13407.6 KFR02042.1 - 0.085 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein domain RRM_1 PF00076.22 KFR02043.1 - 7.9e-16 57.6 0.0 1e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFR02043.1 - 0.017 15.3 0.0 0.023 14.8 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif Glyco_hydro_20 PF00728.22 KFR02044.1 - 2.4e-85 287.0 0.0 3.7e-85 286.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KFR02044.1 - 1e-08 35.9 0.0 1.7e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KFR02044.1 - 0.00033 21.4 0.0 0.00059 20.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 IBR PF01485.21 KFR02045.1 - 9.5e-20 70.6 47.2 3.5e-14 52.8 10.1 5.1 4 1 1 5 5 5 3 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 KFR02045.1 - 4.8e-06 26.3 2.6 4.8e-06 26.3 2.6 4.5 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFR02045.1 - 0.00038 20.3 3.8 0.00038 20.3 3.8 4.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFR02045.1 - 0.0011 18.9 4.2 0.0011 18.9 4.2 4.8 4 1 0 4 4 4 1 RING-type zinc-finger zf-RING_14 PF17978.1 KFR02045.1 - 0.0014 19.1 1.9 0.0014 19.1 1.9 2.5 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 KFR02045.1 - 0.0015 18.9 6.1 0.0015 18.9 6.1 4.6 3 2 0 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 KFR02045.1 - 0.0021 18.2 5.1 0.0021 18.2 5.1 4.7 4 1 1 5 5 5 2 zinc finger of C3HC4-type, RING Med14 PF08638.11 KFR02045.1 - 0.077 12.4 1.2 0.14 11.5 0.4 1.8 2 0 0 2 2 2 0 Mediator complex subunit MED14 TPR_2 PF07719.17 KFR02046.1 - 6.3e-44 144.6 18.4 1.4e-05 24.8 0.0 10.7 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_1 PF00515.28 KFR02046.1 - 3.3e-41 137.4 19.8 1.6e-05 24.5 0.0 9.4 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 KFR02046.1 - 1.8e-36 121.3 18.6 1.9e-05 24.5 0.0 9.5 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_11 PF13414.6 KFR02046.1 - 1.9e-29 101.1 12.7 1.2e-08 34.5 0.0 8.4 3 2 6 9 9 9 5 TPR repeat TPR_19 PF14559.6 KFR02046.1 - 1.2e-26 93.0 5.2 2.9e-06 27.7 0.1 6.9 4 2 1 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFR02046.1 - 5.5e-24 84.5 0.1 0.0013 19.3 0.0 6.9 3 2 3 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFR02046.1 - 5.3e-21 73.5 1.6 0.0011 19.5 0.0 8.2 3 2 6 9 9 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFR02046.1 - 7.4e-21 74.2 20.2 1.8e-05 24.9 0.2 7.9 4 3 3 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.6 KFR02046.1 - 1.4e-19 69.0 15.4 2.7e-05 24.2 0.0 9.0 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFR02046.1 - 3.4e-18 65.5 0.0 1.9e-05 24.7 0.0 5.8 3 2 3 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFR02046.1 - 9.5e-18 64.2 22.7 2.9e-05 24.2 0.7 6.1 2 2 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KFR02046.1 - 7.8e-16 56.9 11.9 0.002 18.0 0.0 8.4 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFR02046.1 - 8.4e-14 51.2 10.2 0.54 11.0 0.0 10.2 10 0 0 10 10 10 2 Tetratricopeptide repeat PknG_TPR PF16918.5 KFR02046.1 - 2.4e-09 36.4 0.9 0.011 14.5 0.0 3.1 2 1 1 3 3 3 3 Protein kinase G tetratricopeptide repeat TPR_15 PF13429.6 KFR02046.1 - 4e-09 36.1 6.3 0.00011 21.5 0.2 4.3 1 1 2 3 3 3 2 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KFR02046.1 - 7.3e-08 32.5 1.8 0.025 14.5 0.0 4.2 2 2 2 4 4 4 2 Virulence factor membrane-bound polymerase, C-terminal NARP1 PF12569.8 KFR02046.1 - 5.6e-07 28.8 10.7 0.0052 15.8 0.2 3.7 3 2 1 4 4 3 3 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 KFR02046.1 - 2.3e-06 27.8 4.0 0.017 15.5 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFR02046.1 - 7.1e-06 25.7 15.5 0.6 10.1 0.1 7.4 8 0 0 8 8 7 1 Tetratricopeptide repeat ChAPs PF09295.10 KFR02046.1 - 5.5e-05 22.3 0.9 0.0047 16.0 0.1 2.8 2 1 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) Coatomer_E PF04733.14 KFR02046.1 - 0.00029 20.3 6.0 0.58 9.5 0.5 3.6 2 1 1 3 3 3 1 Coatomer epsilon subunit ComR_TPR PF18710.1 KFR02046.1 - 0.00095 18.8 0.5 0.33 10.5 0.1 2.6 2 1 0 2 2 2 1 ComR tetratricopeptide TPR_MalT PF17874.1 KFR02046.1 - 0.0017 17.8 3.2 0.1 12.0 0.0 3.4 2 1 1 3 3 3 1 MalT-like TPR region BTAD PF03704.17 KFR02046.1 - 0.0027 18.2 5.3 7.2 7.0 0.9 4.9 3 2 2 5 5 5 0 Bacterial transcriptional activator domain HrpB1_HrpK PF09613.10 KFR02046.1 - 0.01 15.5 0.2 1.7 8.3 0.1 2.8 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF4810 PF16068.5 KFR02046.1 - 0.01 16.4 4.0 26 5.4 0.0 4.7 3 1 2 5 5 3 0 Domain of unknown function (DUF4810) TPR_4 PF07721.14 KFR02046.1 - 0.016 15.8 0.0 96 4.1 0.1 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFR02046.1 - 0.02 14.9 7.9 6.3 7.0 0.0 4.9 4 1 1 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat Mu-like_Pro PF10123.9 KFR02046.1 - 0.021 14.4 3.3 0.098 12.2 2.6 2.3 2 1 0 2 2 2 0 Mu-like prophage I protein DUF627 PF04781.12 KFR02046.1 - 0.024 14.6 4.9 20 5.3 0.2 5.0 3 1 3 6 6 6 0 Protein of unknown function (DUF627) Csm1_B PF18211.1 KFR02046.1 - 0.13 12.2 1.6 3.5 7.5 0.1 3.1 2 1 1 3 3 3 0 Csm1 subunit domain B Clathrin PF00637.20 KFR02046.1 - 0.21 11.4 5.9 3.4 7.5 0.1 3.1 2 1 1 3 3 3 0 Region in Clathrin and VPS ADP_PFK_GK PF04587.15 KFR02047.1 - 6.8e-138 459.8 0.0 7.7e-138 459.6 0.0 1.0 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region Neogenin_C PF06583.12 KFR02048.1 - 3.4e-125 417.7 22.3 6.9e-125 416.7 22.3 1.6 1 0 0 1 1 1 1 Neogenin C-terminus fn3 PF00041.21 KFR02048.1 - 1.3e-83 275.4 28.7 4.5e-18 65.4 0.0 6.5 6 0 0 6 6 6 6 Fibronectin type III domain I-set PF07679.16 KFR02048.1 - 3.6e-55 184.0 0.1 1.7e-16 60.1 0.0 6.7 7 0 0 7 7 7 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR02048.1 - 2.5e-48 162.6 0.4 1.5e-12 47.9 0.0 7.1 6 0 0 6 6 6 4 Immunoglobulin domain Ig_2 PF13895.6 KFR02048.1 - 7.9e-33 112.6 0.0 8.5e-08 32.4 0.0 4.8 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 KFR02048.1 - 3.6e-27 94.4 0.0 3.9e-06 26.9 0.0 6.5 6 1 0 6 6 6 4 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFR02048.1 - 1.4e-21 76.8 23.4 0.0004 20.9 2.9 7.7 6 2 0 6 6 6 5 Purple acid Phosphatase, N-terminal domain V-set PF07686.17 KFR02048.1 - 3.9e-15 55.9 8.4 0.0001 22.4 0.1 9.2 5 4 2 7 7 7 1 Immunoglobulin V-set domain Interfer-bind PF09294.10 KFR02048.1 - 4.4e-13 49.4 0.1 0.083 13.2 0.0 5.9 6 0 0 6 6 6 3 Interferon-alpha/beta receptor, fibronectin type III C2-set_2 PF08205.12 KFR02048.1 - 1.2e-08 34.8 0.0 0.078 13.0 0.0 4.1 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain DUF2369 PF10179.9 KFR02048.1 - 1.7e-08 34.7 1.1 4.4 7.8 0.0 6.1 6 0 0 6 6 6 1 Uncharacterised conserved protein (DUF2369) Ig_5 PF16681.5 KFR02048.1 - 2.3e-06 27.9 0.0 0.43 11.0 0.1 4.6 4 1 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain fn3_4 PF16794.5 KFR02048.1 - 3.2e-06 27.0 0.5 2.4 8.1 0.0 5.6 5 1 0 5 5 5 1 Fibronectin-III type domain fn3_2 PF16893.5 KFR02048.1 - 1.1e-05 25.5 0.0 0.79 9.9 0.0 4.4 4 0 0 4 4 4 1 Fibronectin type III domain Tissue_fac PF01108.17 KFR02048.1 - 1.5e-05 24.8 5.5 0.029 14.2 0.0 5.3 5 1 1 6 6 6 1 Tissue factor SusE PF14292.6 KFR02048.1 - 0.00025 21.2 0.3 0.051 13.8 0.1 4.0 4 0 0 4 4 4 1 SusE outer membrane protein TMEM154 PF15102.6 KFR02048.1 - 0.00088 19.2 1.0 0.0036 17.2 0.0 2.3 2 0 0 2 2 2 1 TMEM154 protein family EphA2_TM PF14575.6 KFR02048.1 - 0.002 19.0 0.3 0.0047 17.8 0.3 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Izumo-Ig PF16706.5 KFR02048.1 - 0.0049 16.9 0.0 0.34 11.0 0.0 3.7 4 1 0 4 4 3 1 Izumo-like Immunoglobulin domain DUF4959 PF16323.5 KFR02048.1 - 0.028 14.7 7.0 1.4 9.3 0.0 3.5 4 0 0 4 4 2 0 Domain of unknown function (DUF4959) Ly49 PF08391.10 KFR02048.1 - 0.038 14.4 0.0 0.076 13.4 0.0 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Herpes_UL74 PF07982.12 KFR02048.1 - 0.042 12.8 2.1 0.074 12.0 2.1 1.3 1 0 0 1 1 1 0 Herpes UL74 glycoproteins Ig_6 PF18452.1 KFR02048.1 - 0.052 13.1 0.0 4.9 6.8 0.0 3.5 4 0 0 4 4 4 0 Immunoglobulin domain Shisa PF13908.6 KFR02048.1 - 0.14 12.3 1.9 0.3 11.3 0.0 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator F5_F8_type_C PF00754.25 KFR02048.1 - 0.27 11.4 4.4 2 8.6 0.1 3.5 4 0 0 4 4 3 0 F5/8 type C domain Insulin_TMD PF17870.1 KFR02048.1 - 1 9.5 4.3 2.8 8.1 4.3 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Ion_trans PF00520.31 KFR02049.1 - 5.1e-23 81.6 15.0 7.2e-23 81.1 15.0 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_N PF08412.10 KFR02049.1 - 3.2e-20 71.5 0.1 6.8e-20 70.4 0.1 1.6 1 0 0 1 1 1 1 Ion transport protein N-terminal cNMP_binding PF00027.29 KFR02049.1 - 2.8e-18 65.8 0.0 5.6e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KFR02049.1 - 0.005 16.8 0.2 0.011 15.6 0.2 1.6 1 0 0 1 1 1 1 Ion channel REC114-like PF15165.6 KFR02050.1 - 2.9e-96 321.9 0.4 3.8e-96 321.4 0.4 1.2 1 0 0 1 1 1 1 Meiotic recombination protein REC114-like DUF1838 PF08894.11 KFR02050.1 - 0.092 12.4 0.1 0.93 9.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1838) Ig_3 PF13927.6 KFR02051.1 - 6.3e-22 78.0 2.8 8.7e-12 45.5 0.2 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFR02051.1 - 1.9e-16 59.9 0.1 5e-12 45.7 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFR02051.1 - 2.6e-10 40.5 4.4 1.5e-05 25.3 0.5 2.2 1 1 1 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFR02051.1 - 2.6e-10 40.3 0.9 1.7e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFR02051.1 - 0.00036 20.7 2.8 1.9 8.7 0.5 3.7 2 2 1 3 3 3 2 Immunoglobulin V-set domain Ig_5 PF16681.5 KFR02051.1 - 0.0013 19.1 0.0 0.53 10.7 0.0 2.4 2 0 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFR02051.1 - 0.0019 18.4 0.0 0.31 11.3 0.0 2.3 2 0 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFR02051.1 - 0.0027 17.2 0.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 KFR02052.1 - 1e-12 48.5 0.1 2.7e-06 27.9 0.2 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFR02052.1 - 1.6e-11 44.2 0.1 1.4e-05 25.2 0.1 2.6 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFR02052.1 - 1.4e-08 34.7 0.1 0.00098 19.1 0.1 2.6 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFR02052.1 - 3.7e-08 33.6 0.8 3.1e-05 24.2 0.2 2.7 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFR02052.1 - 6e-08 32.8 0.1 5e-07 29.9 0.0 2.3 2 1 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFR02052.1 - 2.3e-06 27.6 0.7 5.9e-06 26.3 0.1 2.0 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFR02052.1 - 2.6e-06 27.7 0.1 1.2e-05 25.6 0.0 2.1 3 0 0 3 3 3 1 Immunoglobulin C1-set domain Marek_A PF02124.15 KFR02052.1 - 0.012 15.4 0.3 0.021 14.6 0.3 1.5 1 0 0 1 1 1 0 Marek's disease glycoprotein A DUF4307 PF14155.6 KFR02052.1 - 0.026 14.4 0.9 6.5 6.6 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4307) DUF2371 PF10177.9 KFR02052.1 - 0.027 14.6 0.0 0.046 13.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Ig_6 PF18452.1 KFR02052.1 - 0.1 12.2 0.2 0.58 9.8 0.0 2.2 3 0 0 3 3 3 0 Immunoglobulin domain Zona_pellucida PF00100.23 KFR02053.1 - 6.1e-48 163.9 0.0 7e-48 163.7 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain DUF4589 PF15252.6 KFR02054.1 - 3.4e-81 272.9 10.7 1.7e-72 244.4 0.1 2.8 2 1 1 3 3 3 2 Domain of unknown function (DUF4589) AKNA PF12443.8 KFR02054.1 - 0.054 14.2 0.2 0.13 12.9 0.2 1.7 1 0 0 1 1 1 0 AT-hook-containing transcription factor IFT57 PF10498.9 KFR02054.1 - 0.17 10.8 0.1 0.22 10.5 0.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Lysyl_oxidase PF01186.17 KFR02055.1 - 1.2e-95 319.0 4.3 1.4e-95 318.8 4.3 1.0 1 0 0 1 1 1 1 Lysyl oxidase CARDB PF07705.11 KFR02055.1 - 0.00037 20.7 0.0 0.006 16.8 0.0 2.3 2 0 0 2 2 2 1 CARDB Zona_pellucida PF00100.23 KFR02056.1 - 4.4e-45 154.5 0.0 5.2e-45 154.3 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.23 KFR02057.1 - 7.4e-48 163.6 0.0 8.5e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain DUF3583 PF12126.8 KFR02058.1 - 1.3e-28 100.4 8.5 1.9e-28 99.9 8.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3583) zf-B_box PF00643.24 KFR02058.1 - 2.2e-07 30.9 24.0 5.2e-05 23.3 7.2 3.8 3 1 0 3 3 2 2 B-box zinc finger zf-C3HC4_3 PF13920.6 KFR02058.1 - 2.4e-06 27.3 7.7 2.4e-06 27.3 7.7 3.6 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFR02058.1 - 1.2e-05 25.1 7.5 1.2e-05 25.1 7.5 3.6 3 1 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFR02058.1 - 4.6e-05 23.3 9.4 4.6e-05 23.3 9.4 3.9 3 2 0 3 3 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFR02058.1 - 0.0042 16.9 11.0 0.0042 16.9 11.0 3.9 3 2 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFR02058.1 - 0.0057 16.7 7.4 0.0057 16.7 7.4 3.5 3 2 1 4 4 3 1 RING-type zinc-finger zf-RING_6 PF14835.6 KFR02058.1 - 0.028 14.3 2.3 0.028 14.3 2.3 2.9 3 1 0 3 3 2 0 zf-RING of BARD1-type protein DUF2935 PF11155.8 KFR02058.1 - 0.47 10.8 3.3 4.9 7.5 3.3 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) OmpH PF03938.14 KFR02058.1 - 0.76 10.1 16.3 0.27 11.6 12.5 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Not3 PF04065.15 KFR02058.1 - 0.81 9.1 8.7 1.7 8.0 5.5 2.7 2 2 1 3 3 3 0 Not1 N-terminal domain, CCR4-Not complex component IBR PF01485.21 KFR02058.1 - 0.92 9.8 29.9 0.7 10.2 3.3 4.0 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain Ribosomal_L30_N PF08079.12 KFR02058.1 - 4 7.8 6.2 0.54 10.5 2.1 1.7 2 0 0 2 2 2 0 Ribosomal L30 N-terminal domain SCP2 PF02036.17 KFR02059.1 - 1.4e-16 60.8 0.0 1.1e-15 58.0 0.0 2.2 2 0 0 2 2 2 1 SCP-2 sterol transfer family Band_7 PF01145.25 KFR02059.1 - 1.2e-13 51.5 0.1 2.3e-13 50.5 0.0 1.4 2 0 0 2 2 2 1 SPFH domain / Band 7 family DHQS PF01959.16 KFR02059.1 - 0.044 12.7 0.1 0.058 12.3 0.1 1.1 1 0 0 1 1 1 0 3-dehydroquinate synthase II LRR_8 PF13855.6 KFR02060.1 - 2.5e-20 72.0 8.6 3.8e-11 42.6 1.3 2.2 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFR02060.1 - 2.3e-10 40.5 13.7 0.00012 22.3 2.7 3.4 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFR02060.1 - 2.7e-06 27.0 1.3 0.0033 16.9 0.0 1.9 1 1 1 2 2 2 2 Leucine-rich repeat LRR_5 PF13306.6 KFR02060.1 - 5.8e-06 26.3 0.1 9.9e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFR02060.1 - 0.0011 19.3 7.4 1.5 9.7 0.1 4.7 4 1 0 4 4 4 1 Leucine Rich Repeat TPKR_C2 PF16920.5 KFR02060.1 - 0.0037 17.3 1.2 0.0037 17.3 1.2 2.1 2 0 0 2 2 2 1 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_6 PF13516.6 KFR02060.1 - 1.2 9.3 0.1 1.2 9.3 0.1 3.5 4 0 0 4 4 4 0 Leucine Rich repeat LRR_8 PF13855.6 KFR02061.1 - 1.5e-21 75.9 18.0 3.7e-14 52.2 5.1 2.1 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFR02061.1 - 6.7e-13 48.6 23.8 3.8e-07 30.3 3.7 3.4 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFR02061.1 - 5.9e-07 29.1 1.3 9.4e-07 28.5 1.3 1.4 1 1 0 1 1 1 1 Leucine-rich repeat LRR_5 PF13306.6 KFR02061.1 - 0.00012 22.0 0.0 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFR02061.1 - 0.00057 20.1 12.3 0.44 11.3 0.4 4.5 4 1 0 4 4 4 2 Leucine Rich Repeat TPKR_C2 PF16920.5 KFR02061.1 - 0.0012 19.0 2.4 0.0012 19.0 0.4 2.1 2 1 1 3 3 3 1 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_6 PF13516.6 KFR02061.1 - 0.032 14.3 0.4 0.032 14.3 0.4 4.4 5 0 0 5 5 5 0 Leucine Rich repeat RBP_receptor PF14752.6 KFR02062.1 - 2.1e-241 802.8 19.5 2.5e-241 802.5 19.5 1.0 1 0 0 1 1 1 1 Retinol binding protein receptor Pih1_fungal_CS PF18482.1 KFR02063.1 - 0.14 12.7 0.0 0.25 11.9 0.0 1.5 1 1 0 1 1 1 0 Fungal Pih1 CS domain p450 PF00067.22 KFR02064.1 - 1.1e-23 83.7 0.1 1.2e-23 83.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sema PF01403.19 KFR02065.1 - 1.6e-24 86.5 0.0 1.8e-24 86.4 0.0 1.0 1 0 0 1 1 1 1 Sema domain ubiquitin PF00240.23 KFR02066.1 - 1.4e-08 34.4 0.0 2.9e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KFR02066.1 - 1.8e-05 24.5 0.0 4.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 KFR02066.1 - 0.0076 16.1 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.6 KFR02066.1 - 0.0085 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain Ubiquitin_5 PF18037.1 KFR02066.1 - 0.05 14.0 0.0 0.093 13.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Actin PF00022.19 KFR02067.1 - 5.2e-151 502.9 0.0 1.7e-150 501.2 0.0 1.6 1 1 0 1 1 1 1 Actin ARID PF01388.21 KFR02069.1 - 7.7e-14 52.1 0.0 1.4e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Pkinase PF00069.25 KFR02070.1 - 4.9e-47 160.5 0.1 6.1e-47 160.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR02070.1 - 1.5e-22 80.2 0.1 5.5e-21 75.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Edc3_linker PF16598.5 KFR02071.1 - 2.8e-45 152.9 5.2 5.2e-45 152.0 5.2 1.5 1 0 0 1 1 1 1 Linker region of enhancer of mRNA-decapping protein 3 YjeF_N PF03853.15 KFR02071.1 - 8.6e-20 71.3 0.0 1.4e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 KFR02071.1 - 8.7e-16 58.7 0.0 1.8e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 FDF domain LSM14 PF12701.7 KFR02071.1 - 3.1e-10 40.0 0.0 8.3e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 Scd6-like Sm domain DUF5096 PF17019.5 KFR02071.1 - 0.0057 16.5 0.0 0.0095 15.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5096) Synaphin PF05835.12 KFR02072.1 - 1.3e-47 161.6 11.4 1.6e-47 161.4 11.4 1.1 1 0 0 1 1 1 1 Synaphin protein Pkinase PF00069.25 KFR02073.1 - 3.5e-65 220.0 0.0 8.5e-65 218.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR02073.1 - 2.1e-38 132.1 0.0 3e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MIT PF04212.18 KFR02073.1 - 8.3e-33 112.3 15.4 2.6e-20 72.3 2.6 2.9 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain Kdo PF06293.14 KFR02073.1 - 2.3e-05 23.9 0.1 5e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFR02073.1 - 0.072 12.7 0.0 0.22 11.1 0.0 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 KFR02073.1 - 0.13 12.2 1.7 0.21 11.5 0.1 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Use1 PF09753.9 KFR02073.1 - 0.46 10.2 4.5 0.64 9.7 2.3 1.9 1 1 1 2 2 2 0 Membrane fusion protein Use1 SCAMP PF04144.13 KFR02074.1 - 3.1e-66 223.0 13.3 3.9e-66 222.7 13.3 1.1 1 0 0 1 1 1 1 SCAMP family DUF3552 PF12072.8 KFR02074.1 - 0.0089 15.5 0.3 0.017 14.6 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DUF3736 PF12540.8 KFR02074.1 - 0.075 13.2 0.3 0.11 12.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3736) KfrA_N PF11740.8 KFR02074.1 - 0.28 11.9 7.5 0.65 10.7 7.5 1.5 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term HemY_N PF07219.13 KFR02074.1 - 2.5 8.3 6.0 0.29 11.3 0.7 2.3 2 0 0 2 2 2 0 HemY protein N-terminus DUF737 PF05300.11 KFR02074.1 - 9.8 6.5 9.1 2.1 8.7 4.1 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF737) PMI_typeI PF01238.21 KFR02075.1 - 1.9e-127 425.5 0.0 3.1e-127 424.8 0.0 1.3 1 1 0 1 1 1 1 Phosphomannose isomerase type I FAM219A PF15260.6 KFR02076.1 - 1.4e-50 170.9 0.4 2e-50 170.3 0.4 1.2 1 1 0 1 1 1 1 Protein family FAM219A COX5A PF02284.16 KFR02077.1 - 5.3e-47 158.1 0.0 6e-47 157.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Alba PF01918.21 KFR02078.1 - 1.9e-19 69.2 1.1 2.5e-19 68.9 1.1 1.1 1 0 0 1 1 1 1 Alba DUF4147 PF13660.6 KFR02078.1 - 0.073 12.6 0.0 0.085 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) STAT2_C PF12188.8 KFR02078.1 - 0.14 12.1 0.8 0.25 11.3 0.1 1.7 2 0 0 2 2 2 0 Signal transducer and activator of transcription 2 C terminal SCAMP PF04144.13 KFR02079.1 - 1.4e-68 230.6 16.6 1.7e-68 230.4 16.6 1.1 1 0 0 1 1 1 1 SCAMP family Flavoprotein PF02441.19 KFR02080.1 - 1.3e-51 174.5 0.0 1.5e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein DUF5525 PF17663.1 KFR02081.1 - 8.3e-74 249.3 2.8 3.7e-63 214.0 1.0 2.0 1 1 1 2 2 2 2 Family of unknown function (DUF5525) COMM_domain PF07258.14 KFR02083.1 - 4.3e-18 65.2 0.0 7.5e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 COMM domain Neil1-DNA_bind PF09292.10 KFR02084.1 - 8.8e-26 89.6 0.8 2e-25 88.5 0.4 1.8 2 0 0 2 2 2 1 Endonuclease VIII-like 1, DNA bind H2TH PF06831.14 KFR02084.1 - 1.6e-07 31.2 0.0 2.1e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Glyco_hydro_38N PF01074.22 KFR02085.1 - 6e-88 295.0 0.1 1e-87 294.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KFR02085.1 - 8.8e-52 176.3 0.0 1.4e-51 175.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KFR02085.1 - 3.8e-27 94.3 0.2 1.5e-26 92.4 0.0 2.0 2 0 0 2 2 2 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KFR02085.1 - 9.2e-09 35.3 0.0 2.2e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain MHCassoc_trimer PF08831.10 KFR02085.1 - 1.1 9.3 5.1 4 7.5 5.1 1.9 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain Y_phosphatase PF00102.27 KFR02086.1 - 1.9e-80 269.9 0.0 2.6e-80 269.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CRAL_TRIO PF00650.20 KFR02086.1 - 7.3e-31 107.0 0.1 1.9e-30 105.7 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFR02086.1 - 1.1e-11 45.1 0.0 2.2e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DSPc PF00782.20 KFR02086.1 - 0.0055 16.5 0.7 0.016 15.1 0.1 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFR02086.1 - 0.0056 16.7 0.0 0.009 16.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family CRAL_TRIO_N PF03765.15 KFR02086.1 - 0.036 14.3 0.5 0.34 11.1 0.0 2.7 3 0 0 3 3 3 0 CRAL/TRIO, N-terminal domain PTPlike_phytase PF14566.6 KFR02086.1 - 0.14 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate mRNA_cap_enzyme PF01331.19 KFR02087.1 - 0.0023 17.8 0.0 0.004 17.0 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain Snurportin1 PF11538.8 KFR02087.1 - 0.12 12.6 1.9 0.23 11.7 1.9 1.5 1 0 0 1 1 1 0 Snurportin1 BAR_3_WASP_bdg PF10456.9 KFR02088.1 - 1.6e-109 364.9 4.5 2e-109 364.6 4.5 1.1 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.24 KFR02088.1 - 1.4e-20 73.4 4.0 3.2e-20 72.2 1.3 2.3 2 0 0 2 2 2 1 PX domain SH3_9 PF14604.6 KFR02088.1 - 5.4e-12 45.4 0.0 1.3e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFR02088.1 - 3.7e-10 39.2 0.0 9e-10 38.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFR02088.1 - 9.8e-09 34.8 0.0 3e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Vps5 PF09325.10 KFR02088.1 - 1.7e-05 24.5 3.0 0.0018 17.9 1.5 3.0 1 1 1 2 2 2 2 Vps5 C terminal like Cadherin_3 PF16184.5 KFR02089.1 - 5.5e-202 657.4 10.6 6.4e-31 106.6 0.0 14.2 14 0 0 14 14 14 14 Cadherin-like Cadherin_4 PF17803.1 KFR02089.1 - 0.0015 19.1 0.8 18 6.1 0.0 5.0 4 1 0 4 4 4 1 Bacterial cadherin-like domain DUF2152 PF10222.9 KFR02089.1 - 0.17 10.2 0.2 0.39 9.0 0.2 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2152) LRR_8 PF13855.6 KFR02090.1 - 3.7e-53 177.1 50.6 2.3e-12 46.5 1.7 6.4 1 1 4 6 6 6 6 Leucine rich repeat LRR_5 PF13306.6 KFR02090.1 - 2.3e-28 98.7 0.3 4e-12 46.2 0.0 3.1 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFR02090.1 - 3.6e-20 71.7 34.5 0.00019 21.7 2.1 7.3 5 1 2 7 7 7 7 Leucine Rich repeats (2 copies) I-set PF07679.16 KFR02090.1 - 1.5e-14 53.8 0.0 2.7e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR02090.1 - 5.1e-12 46.2 0.0 1.1e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFR02090.1 - 3e-08 33.7 0.0 5.5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFR02090.1 - 1.2e-07 32.0 0.0 2.5e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.6 KFR02090.1 - 1.5e-06 27.8 14.1 0.00046 19.7 2.7 3.6 2 2 1 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 KFR02090.1 - 6.4e-06 26.0 37.8 11 7.1 0.0 11.8 12 1 0 12 12 12 2 Leucine Rich Repeat LRRNT PF01462.18 KFR02090.1 - 0.032 13.9 8.7 0.025 14.3 2.8 3.2 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain V-set PF07686.17 KFR02090.1 - 0.19 11.9 0.0 0.87 9.8 0.0 2.1 1 1 0 1 1 1 0 Immunoglobulin V-set domain LRR_6 PF13516.6 KFR02090.1 - 0.43 10.8 36.9 6.4 7.1 0.1 10.0 11 0 0 11 11 11 0 Leucine Rich repeat HMG_box PF00505.19 KFR02091.1 - 3.3e-19 69.1 1.4 9.6e-19 67.6 1.4 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFR02091.1 - 1.1e-12 48.4 3.9 1.6e-12 47.9 0.7 2.5 1 1 1 2 2 2 1 HMG-box domain DUF4763 PF15960.5 KFR02091.1 - 0.0027 17.0 3.7 0.0027 17.0 3.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4763) Trans_reg_C PF00486.28 KFR02091.1 - 0.0029 17.6 0.3 0.62 10.2 0.0 3.2 2 1 1 3 3 3 1 Transcriptional regulatory protein, C terminal COG5 PF10392.9 KFR02091.1 - 0.084 13.1 3.9 0.082 13.1 2.3 1.7 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DivIC PF04977.15 KFR02091.1 - 1.4 8.7 5.3 2.1 8.2 3.1 2.5 2 1 0 2 2 2 0 Septum formation initiator Lectin_N PF03954.14 KFR02091.1 - 3 7.6 6.9 5.6 6.7 3.9 2.7 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Pkinase PF00069.25 KFR02092.1 - 1.4e-12 47.5 0.0 2.8e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR02092.1 - 4.7e-06 26.1 0.0 1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFR02092.1 - 0.089 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tetraspanin PF00335.20 KFR02093.1 - 4.8e-44 150.8 11.5 5.5e-44 150.6 11.5 1.0 1 0 0 1 1 1 1 Tetraspanin family SUR7 PF06687.12 KFR02093.1 - 0.0078 15.9 6.2 0.036 13.7 1.8 2.2 2 0 0 2 2 2 1 SUR7/PalI family COX2_TM PF02790.15 KFR02093.1 - 0.015 15.5 3.5 3.3 7.9 0.1 3.2 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain DUF1616 PF07760.11 KFR02093.1 - 0.1 12.0 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) DUF996 PF06195.13 KFR02093.1 - 0.22 11.8 8.7 0.045 14.0 4.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF996) Hum_adeno_E3A PF05393.11 KFR02093.1 - 0.29 11.1 3.9 0.7 9.9 0.4 2.3 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein DUF2207 PF09972.9 KFR02093.1 - 4.4 5.9 5.0 1.6 7.4 1.3 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) ECSCR PF15820.5 KFR02093.1 - 7.8 6.4 7.0 1.3 8.9 2.5 1.9 1 1 1 2 2 2 0 Endothelial cell-specific chemotaxis regulator SH3_9 PF14604.6 KFR02094.1 - 3.3e-17 62.1 1.4 5.9e-17 61.3 0.2 2.1 3 0 0 3 3 3 1 Variant SH3 domain SH3_1 PF00018.28 KFR02094.1 - 1.4e-16 59.8 1.4 1.6e-16 59.6 0.2 1.8 2 0 0 2 2 2 1 SH3 domain FCH PF00611.23 KFR02094.1 - 2.2e-14 53.5 0.4 2.2e-14 53.5 0.4 2.5 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.17 KFR02094.1 - 1.6e-12 46.9 0.2 4.3e-12 45.5 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.11 KFR02094.1 - 0.0031 17.8 0.4 0.0057 16.9 0.4 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain DUF4265 PF14085.6 KFR02094.1 - 0.32 11.0 2.5 2.7 8.0 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4265) EF-hand_1 PF00036.32 KFR02095.1 - 9.6e-19 65.5 17.9 2.2e-05 23.7 0.2 6.2 6 1 1 7 7 7 5 EF hand EF-hand_7 PF13499.6 KFR02095.1 - 1.7e-18 66.8 17.0 4.2e-07 30.3 0.6 3.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KFR02095.1 - 2.8e-17 61.1 11.0 0.0015 18.3 0.1 5.6 5 1 0 5 5 5 5 EF-hand domain EF-hand_5 PF13202.6 KFR02095.1 - 1.2e-15 56.2 9.6 0.0023 17.3 0.3 5.4 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 KFR02095.1 - 1.9e-07 30.8 12.9 0.024 14.5 0.3 4.6 4 2 1 5 5 5 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFR02095.1 - 0.037 14.4 10.2 2.8 8.3 0.5 3.9 2 2 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region SCAPER_N PF16501.5 KFR02096.1 - 3.6e-44 148.8 0.3 3.6e-44 148.8 0.3 2.8 2 0 0 2 2 2 1 S phase cyclin A-associated protein in the endoplasmic reticulum zf-met PF12874.7 KFR02096.1 - 5.9e-07 29.7 1.7 2.1e-06 27.9 1.7 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFR02096.1 - 0.0097 16.2 0.9 0.034 14.4 0.9 2.0 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF5487 PF17589.2 KFR02096.1 - 0.17 12.1 0.1 0.4 11.0 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5487) ETF PF01012.21 KFR02097.1 - 1.1e-41 142.8 0.1 1.5e-41 142.3 0.1 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KFR02097.1 - 6.5e-38 128.6 1.2 1.1e-37 128.0 0.3 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain Ion_trans PF00520.31 KFR02098.1 - 2.8e-07 30.0 7.3 4e-07 29.5 7.3 1.1 1 0 0 1 1 1 1 Ion transport protein zf-C4H2 PF10146.9 KFR02098.1 - 0.12 12.7 0.2 0.2 11.9 0.2 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein EGF PF00008.27 KFR02099.1 - 0.0018 18.6 5.9 0.0018 18.6 5.9 1.6 2 0 0 2 2 2 1 EGF-like domain EGF_2 PF07974.13 KFR02099.1 - 0.013 15.9 3.1 0.013 15.9 3.1 2.1 2 1 0 2 2 2 0 EGF-like domain Laminin_EGF PF00053.24 KFR02099.1 - 0.076 13.2 0.7 0.076 13.2 0.7 1.9 2 0 0 2 2 2 0 Laminin EGF domain SH3_2 PF07653.17 KFR02099.1 - 0.094 12.4 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain FIST_C PF10442.9 KFR02101.1 - 2.4e-12 46.9 0.1 5.2e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 FIST C domain FIST PF08495.10 KFR02101.1 - 3.3e-05 24.0 0.0 0.012 15.6 0.0 2.2 2 0 0 2 2 2 2 FIST N domain Toprim_3 PF13362.6 KFR02101.1 - 0.048 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Toprim domain UQ_con PF00179.26 KFR02102.1 - 8.7e-11 41.6 0.0 9.4e-10 38.3 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFR02102.1 - 0.016 14.9 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B Josephin PF02099.17 KFR02102.1 - 0.036 14.2 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 Josephin KIAA1430 PF13879.6 KFR02102.1 - 0.037 14.8 2.1 2 9.2 0.1 2.9 3 0 0 3 3 3 0 KIAA1430 homologue TraC_F_IV PF11130.8 KFR02102.1 - 0.11 12.0 0.0 7.3 6.1 0.0 2.3 2 1 0 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer TPR_MLP1_2 PF07926.12 KFR02102.1 - 0.92 9.6 4.4 0.62 10.1 0.5 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Neur_chan_memb PF02932.16 KFR02103.1 - 2.6e-85 286.3 16.2 4.2e-63 213.6 12.2 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFR02103.1 - 1.4e-74 250.2 1.3 2.1e-74 249.6 1.3 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain FtsK_alpha PF17854.1 KFR02103.1 - 0.066 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 FtsK alpha domain Neur_chan_LBD PF02931.23 KFR02104.1 - 2.1e-72 243.1 0.6 2.7e-72 242.7 0.6 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFR02104.1 - 1.1e-64 218.7 14.1 9.4e-51 173.2 9.4 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Proteasome PF00227.26 KFR02105.1 - 2.4e-55 187.0 0.0 3.1e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFR02105.1 - 8.1e-14 51.0 0.1 1.3e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Phenol_monoox PF04663.12 KFR02105.1 - 0.12 12.6 0.1 0.27 11.4 0.1 1.6 1 0 0 1 1 1 0 Phenol hydroxylase conserved region TRP_N PF14558.6 KFR02105.1 - 0.12 12.8 0.1 0.55 10.6 0.0 1.9 2 0 0 2 2 2 0 ML-like domain APH PF01636.23 KFR02106.1 - 1.2e-23 84.3 0.0 1.6e-23 83.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFR02106.1 - 0.044 13.1 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Kdo PF06293.14 KFR02106.1 - 0.064 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aconitase PF00330.20 KFR02107.1 - 7.5e-156 519.7 0.0 9.9e-156 519.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KFR02107.1 - 1.1e-40 138.9 0.0 1.9e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Lipocalin PF00061.23 KFR02108.1 - 6.2e-17 62.1 0.3 6.7e-17 62.0 0.3 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family WD40 PF00400.32 KFR02109.1 - 1.4e-42 142.9 24.8 1.9e-09 38.0 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR02109.1 - 2.4e-24 85.4 2.0 8.2e-06 26.0 0.0 6.4 2 1 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFR02109.1 - 1.8e-08 33.7 3.7 0.022 13.7 0.0 4.8 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KFR02109.1 - 2.1e-06 26.5 1.9 0.78 8.2 0.0 3.7 1 1 1 3 3 3 3 Cytochrome D1 heme domain Nup160 PF11715.8 KFR02109.1 - 9.4e-06 24.5 0.1 0.017 13.8 0.0 2.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PD40 PF07676.12 KFR02109.1 - 0.00011 22.0 0.1 1.4 9.0 0.0 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat HPS3_N PF14761.6 KFR02109.1 - 0.00037 20.1 0.0 0.14 11.7 0.0 3.0 3 0 0 3 3 3 1 Hermansky-Pudlak syndrome 3 WD40_like PF17005.5 KFR02109.1 - 0.00078 18.9 0.1 0.5 9.6 0.0 3.2 2 1 1 3 3 3 1 WD40-like domain GSDH PF07995.11 KFR02109.1 - 0.0046 16.3 0.0 0.42 9.9 0.0 2.4 1 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase Frtz PF11768.8 KFR02109.1 - 0.0046 15.3 0.0 0.016 13.5 0.0 1.8 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz DUF2415 PF10313.9 KFR02109.1 - 0.028 14.4 0.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) PQQ PF01011.21 KFR02109.1 - 0.029 14.3 2.8 7.2 6.7 0.0 4.0 4 0 0 4 4 4 0 PQQ enzyme repeat PALB2_WD40 PF16756.5 KFR02109.1 - 0.049 12.5 0.7 3.6 6.4 0.1 2.9 2 1 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain DnaJ_C PF01556.18 KFR02110.1 - 6.8e-45 152.8 0.8 8.5e-45 152.5 0.8 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KFR02110.1 - 1e-14 54.6 19.1 1.8e-14 53.8 19.1 1.4 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.31 KFR02110.1 - 3.9e-05 23.7 0.1 6.5e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Anti-TRAP PF15777.5 KFR02110.1 - 0.0092 15.9 11.8 0.17 11.8 1.3 2.7 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KFR02110.1 - 0.021 14.8 5.0 2.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 KFR02110.1 - 0.11 12.1 7.2 0.94 9.1 2.6 2.1 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zf-RING_10 PF16685.5 KFR02110.1 - 0.27 11.4 10.1 0.19 11.9 6.6 2.1 1 1 1 2 2 2 0 zinc RING finger of MSL2 zf_CopZ PF18423.1 KFR02110.1 - 0.29 11.1 4.6 9.6 6.3 0.3 2.6 2 0 0 2 2 2 0 Zinc binding domain PADR1 PF08063.12 KFR02110.1 - 0.81 9.5 8.5 0.94 9.3 0.1 3.4 3 0 0 3 3 3 0 PADR1 (NUC008) domain RseC_MucC PF04246.12 KFR02110.1 - 0.92 9.5 5.6 0.097 12.6 0.8 1.8 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF2614 PF11023.8 KFR02110.1 - 3.5 7.7 5.4 3.4 7.8 0.8 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain AMP-binding PF00501.28 KFR02111.1 - 4.3e-92 308.9 0.0 5.1e-92 308.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Iso_dh PF00180.20 KFR02112.1 - 2.8e-112 375.3 0.0 3.2e-112 375.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase EF-hand_7 PF13499.6 KFR02113.1 - 6.7e-13 48.9 2.9 5.7e-10 39.5 0.8 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFR02113.1 - 9.8e-09 34.2 10.1 9e-05 21.7 0.5 3.5 3 1 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KFR02113.1 - 1.1e-08 34.3 7.1 0.0042 16.9 0.4 3.6 2 1 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 KFR02113.1 - 4e-05 23.4 7.7 0.01 15.6 1.9 2.8 2 1 0 2 2 2 2 EF-hand domain pair PMBR PF09373.10 KFR02113.1 - 0.018 15.2 0.0 6.6 7.1 0.0 3.3 3 0 0 3 3 3 0 Pseudomurein-binding repeat EF-hand_5 PF13202.6 KFR02113.1 - 0.024 14.1 12.3 0.041 13.4 0.8 3.9 4 1 1 5 5 5 0 EF hand Dockerin_1 PF00404.18 KFR02113.1 - 0.14 12.4 0.1 0.36 11.1 0.1 1.7 1 1 0 1 1 1 0 Dockerin type I domain EF-hand_4 PF12763.7 KFR02113.1 - 0.15 12.0 1.0 1.2 9.1 0.1 2.2 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand RabGAP-TBC PF00566.18 KFR02114.1 - 7.6e-58 195.7 3.8 2.2e-57 194.2 3.8 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain KRAB PF01352.27 KFR02114.1 - 0.0025 17.4 0.4 0.014 15.0 0.2 2.4 2 0 0 2 2 2 1 KRAB box DUF1664 PF07889.12 KFR02114.1 - 0.021 14.9 13.5 0.087 12.9 1.5 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KFR02114.1 - 1.8 7.4 26.6 1.2 7.9 14.9 2.8 1 1 0 2 2 2 0 Spc7 kinetochore protein FAM76 PF16046.5 KFR02114.1 - 2.1 7.6 18.8 2.1 7.6 16.4 2.2 1 1 1 2 2 2 0 FAM76 protein DivIC PF04977.15 KFR02114.1 - 4.6 7.1 26.2 0.26 11.1 5.4 4.3 3 1 1 4 4 4 0 Septum formation initiator HIP1_clath_bdg PF16515.5 KFR02114.1 - 8.5 7.1 29.7 0.048 14.3 6.2 4.7 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF724 PF05266.14 KFR02114.1 - 9.1 6.1 21.3 0.081 12.8 3.7 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF724) Pkinase PF00069.25 KFR02115.1 - 2e-75 253.6 0.1 2.9e-75 253.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR02115.1 - 3.3e-36 124.9 0.0 4.2e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KFR02115.1 - 4.2e-05 23.2 0.2 7.1e-05 22.5 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KFR02115.1 - 0.00024 20.5 0.2 0.00024 20.5 0.2 1.7 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KFR02115.1 - 0.018 14.7 0.2 3.8 7.1 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Glycos_trans_3N PF02885.17 KFR02115.1 - 0.087 12.7 0.3 0.48 10.3 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain NUC129 PF08157.11 KFR02115.1 - 0.1 12.9 0.2 2.9 8.3 0.0 3.0 3 0 0 3 3 3 0 NUC129 domain LRR_6 PF13516.6 KFR02116.1 - 0.00045 20.1 3.3 5.7 7.3 0.1 3.7 3 0 0 3 3 3 2 Leucine Rich repeat F-box-like PF12937.7 KFR02116.1 - 0.01 15.7 0.2 0.019 14.8 0.2 1.5 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.7 KFR02116.1 - 0.037 14.5 7.1 0.22 12.0 3.4 3.3 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFR02116.1 - 0.95 10.3 6.5 42 5.3 0.0 4.6 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_2 PF07723.13 KFR02116.1 - 2.7 8.8 8.5 10 7.0 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat UCH PF00443.29 KFR02117.1 - 1.7e-62 211.3 0.3 2.6e-62 210.6 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFR02117.1 - 4.8e-22 79.0 5.6 2.6e-21 76.6 0.1 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFR02117.1 - 3.1e-19 69.1 11.4 3.1e-19 69.1 11.4 2.9 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein zf-AD PF07776.15 KFR02117.1 - 5.8 7.2 14.2 2 8.7 3.4 3.0 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Carb_anhydrase PF00194.21 KFR02118.1 - 5.2e-87 291.6 0.0 5.8e-87 291.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Ras PF00071.22 KFR02119.1 - 3.7e-51 172.9 0.4 4.6e-51 172.6 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR02119.1 - 4.5e-22 78.5 0.1 8.3e-22 77.7 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR02119.1 - 1.2e-11 44.4 0.4 1.4e-11 44.2 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFR02119.1 - 0.00022 20.8 0.0 0.00028 20.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF3963 PF13124.6 KFR02119.1 - 0.018 15.0 0.8 0.034 14.1 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) Gtr1_RagA PF04670.12 KFR02119.1 - 0.031 13.6 0.1 0.038 13.3 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ribosomal_S27e PF01667.17 KFR02120.1 - 1.1e-30 105.0 5.1 1.4e-30 104.7 5.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 DUF3795 PF12675.7 KFR02120.1 - 0.034 14.6 2.2 0.13 12.7 2.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) Beta-lactamase PF00144.24 KFR02121.1 - 1.4e-51 175.7 0.0 9.5e-28 97.4 0.0 2.0 2 0 0 2 2 2 2 Beta-lactamase Peptidase_S11 PF00768.20 KFR02121.1 - 0.021 14.3 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 KFR02121.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase enzyme family Tropomyosin PF00261.20 KFR02122.1 - 3.9e-99 330.8 61.8 4.4e-99 330.7 61.8 1.0 1 0 0 1 1 1 1 Tropomyosin Tropomyosin_1 PF12718.7 KFR02122.1 - 1.1e-30 106.7 61.9 2.1e-26 92.8 29.0 3.1 1 1 1 2 2 2 2 Tropomyosin like Laminin_II PF06009.12 KFR02122.1 - 1.2e-07 31.8 30.9 1.7e-05 24.9 7.1 3.6 1 1 3 4 4 4 3 Laminin Domain II TMF_DNA_bd PF12329.8 KFR02122.1 - 6.2e-05 22.9 18.4 0.00049 20.0 9.2 5.5 2 2 3 5 5 5 3 TATA element modulatory factor 1 DNA binding DUF745 PF05335.13 KFR02122.1 - 9.5e-05 22.2 38.4 0.0078 15.9 17.9 2.9 1 1 2 3 3 3 3 Protein of unknown function (DUF745) XhlA PF10779.9 KFR02122.1 - 0.0003 20.9 46.3 0.016 15.4 3.7 5.9 2 2 3 6 6 6 2 Haemolysin XhlA ERM PF00769.19 KFR02122.1 - 0.00057 19.8 62.7 0.058 13.2 33.1 2.0 1 1 1 2 2 2 2 Ezrin/radixin/moesin family Laminin_I PF06008.14 KFR02122.1 - 0.0018 18.0 42.7 0.042 13.5 5.2 3.1 1 1 2 3 3 3 2 Laminin Domain I CENP-F_leu_zip PF10473.9 KFR02122.1 - 0.0032 17.5 30.8 0.0032 17.5 30.8 2.4 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.6 KFR02122.1 - 0.0055 16.4 51.7 1.9 8.1 27.1 2.7 1 1 2 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease TTKRSYEDQ PF10212.9 KFR02122.1 - 0.0071 15.4 5.0 0.0071 15.4 5.0 2.2 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein MscS_porin PF12795.7 KFR02122.1 - 0.011 15.3 41.3 0.38 10.3 6.4 3.0 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain SNARE PF05739.19 KFR02122.1 - 0.016 15.2 5.4 1.9 8.5 0.1 4.2 4 0 0 4 4 4 0 SNARE domain DUF16 PF01519.16 KFR02122.1 - 0.018 15.5 34.7 0.39 11.2 0.4 4.1 1 1 3 4 4 4 0 Protein of unknown function DUF16 DHR10 PF18595.1 KFR02122.1 - 0.019 15.0 18.3 0.019 15.0 18.3 3.5 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain DUF1664 PF07889.12 KFR02122.1 - 0.022 14.8 26.5 0.17 12.0 3.7 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) DUF1110 PF06533.12 KFR02122.1 - 0.028 14.4 15.4 0.017 15.1 9.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1110) Golgin_A5 PF09787.9 KFR02122.1 - 0.03 13.8 46.3 0.29 10.6 21.1 2.8 1 1 2 3 3 3 0 Golgin subfamily A member 5 ATG16 PF08614.11 KFR02122.1 - 0.03 14.5 52.6 0.32 11.2 12.6 3.3 1 1 1 2 2 1 0 Autophagy protein 16 (ATG16) CLZ PF16526.5 KFR02122.1 - 0.037 14.4 40.0 1.7 9.1 1.9 5.0 1 1 3 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GAS PF13851.6 KFR02122.1 - 0.045 13.1 50.0 0.19 11.1 16.1 2.7 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding T3SSipB PF16535.5 KFR02122.1 - 0.049 14.1 36.1 7.2 7.1 4.6 3.8 1 1 3 4 4 4 0 Type III cell invasion protein SipB EzrA PF06160.12 KFR02122.1 - 0.059 11.5 48.3 0.1 10.8 7.4 3.1 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA SlyX PF04102.12 KFR02122.1 - 0.082 13.5 40.2 0.24 12.0 3.5 5.1 1 1 4 5 5 4 0 SlyX Fez1 PF06818.15 KFR02122.1 - 0.085 13.3 44.6 21 5.5 27.9 2.7 1 1 1 2 2 2 0 Fez1 MAD PF05557.13 KFR02122.1 - 0.23 9.8 47.3 0.67 8.2 10.7 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein AAA_13 PF13166.6 KFR02122.1 - 0.23 10.1 41.0 0.12 11.1 32.4 2.0 1 1 1 2 2 2 0 AAA domain ADIP PF11559.8 KFR02122.1 - 0.25 11.4 41.0 2.1 8.4 8.4 4.1 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding DUF1794 PF08768.11 KFR02122.1 - 0.26 11.3 4.9 6.4 6.7 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1794) Fib_alpha PF08702.10 KFR02122.1 - 0.28 11.4 28.4 0.1 12.8 6.9 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 KFR02122.1 - 0.35 10.4 30.3 1.9 8.0 13.9 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit Uds1 PF15456.6 KFR02122.1 - 0.84 9.8 40.4 0.36 11.0 9.1 4.2 1 1 2 3 3 3 0 Up-regulated During Septation FliJ PF02050.16 KFR02122.1 - 0.99 9.6 39.1 5.6 7.2 18.2 3.3 1 1 2 3 3 3 0 Flagellar FliJ protein BRE1 PF08647.11 KFR02122.1 - 1 9.5 52.8 1.1 9.4 8.5 4.1 1 1 3 4 4 4 0 BRE1 E3 ubiquitin ligase DUF3584 PF12128.8 KFR02122.1 - 1.2 6.5 48.5 1.7 6.1 13.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Spectrin PF00435.21 KFR02122.1 - 1.4 9.4 40.0 0.49 10.9 6.9 4.2 1 1 3 4 4 4 0 Spectrin repeat Uso1_p115_C PF04871.13 KFR02122.1 - 1.6 9.1 57.6 2.3 8.6 17.4 3.6 1 1 2 3 3 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Flagellin_C PF00700.21 KFR02122.1 - 1.8 9.0 13.5 0.48 10.8 1.0 3.9 1 1 3 4 4 4 0 Bacterial flagellin C-terminal helical region FbpA PF05833.11 KFR02122.1 - 1.9 7.1 40.8 3.4 6.3 40.8 1.5 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) CC2-LZ PF16516.5 KFR02122.1 - 2.7 8.4 43.6 2.9 8.3 5.4 4.9 1 1 2 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator TPR_MLP1_2 PF07926.12 KFR02122.1 - 2.8 8.0 60.1 1.8 8.6 21.7 3.5 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.12 KFR02122.1 - 2.9 8.4 17.5 9.4 6.8 0.8 4.4 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein COG2 PF06148.11 KFR02122.1 - 3.1 7.9 31.1 0.089 12.9 1.9 4.0 1 1 3 4 4 3 0 COG (conserved oligomeric Golgi) complex component, COG2 APG6_N PF17675.1 KFR02122.1 - 3.2 8.3 62.9 14 6.2 28.1 3.2 1 1 1 2 2 2 0 Apg6 coiled-coil region HOOK PF05622.12 KFR02122.1 - 3.2 5.8 49.1 6.8 4.7 49.1 1.5 1 1 0 1 1 1 0 HOOK protein TMPIT PF07851.13 KFR02122.1 - 3.3 6.9 36.0 0.13 11.4 11.0 2.9 1 1 2 3 3 3 0 TMPIT-like protein FH2 PF02181.23 KFR02122.1 - 3.7 6.6 33.5 0.5 9.4 9.7 3.0 1 1 2 3 3 3 0 Formin Homology 2 Domain FPP PF05911.11 KFR02122.1 - 3.8 5.6 50.9 1.7 6.7 6.7 2.9 1 1 2 3 3 3 0 Filament-like plant protein, long coiled-coil Leu_zip PF15294.6 KFR02122.1 - 3.8 6.9 42.3 0.31 10.5 19.2 2.7 1 1 1 2 2 1 0 Leucine zipper BST2 PF16716.5 KFR02122.1 - 3.9 8.1 42.8 0.087 13.4 11.1 4.4 1 1 4 5 5 5 0 Bone marrow stromal antigen 2 DUF2721 PF11026.8 KFR02122.1 - 4.5 7.2 5.3 18 5.3 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) BLOC1_2 PF10046.9 KFR02122.1 - 4.8 7.5 33.2 0.9 9.9 9.3 4.3 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EMP24_GP25L PF01105.24 KFR02122.1 - 4.9 7.0 27.8 1.4 8.9 0.9 4.1 2 2 2 4 4 4 0 emp24/gp25L/p24 family/GOLD DUF3450 PF11932.8 KFR02122.1 - 5 6.4 40.5 0.025 13.9 10.1 3.0 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) HrpB7 PF09486.10 KFR02122.1 - 5.4 7.4 41.6 0.62 10.4 12.5 4.2 1 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) Spc7 PF08317.11 KFR02122.1 - 5.6 5.7 54.5 0.57 9.0 15.2 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF4472 PF14739.6 KFR02122.1 - 6.1 7.6 44.0 0.26 12.0 7.5 3.8 1 1 2 3 3 2 0 Domain of unknown function (DUF4472) FlaC_arch PF05377.11 KFR02122.1 - 7.1 7.1 31.4 1.3 9.5 2.7 5.4 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) Noelin-1 PF12308.8 KFR02122.1 - 9.2 6.3 15.0 8.2 6.5 1.1 3.5 1 1 5 6 6 6 0 Neurogenesis glycoprotein VBS PF08913.10 KFR02123.1 - 2.8e-65 218.4 108.5 2.6e-64 215.3 0.5 12.5 12 2 2 14 14 14 6 Vinculin Binding Site I_LWEQ PF01608.17 KFR02123.1 - 8.9e-64 214.3 200.3 2.5e-48 164.2 15.4 19.4 9 4 8 19 19 19 9 I/LWEQ domain Talin_middle PF09141.10 KFR02123.1 - 6.2e-55 185.6 4.0 6.2e-55 185.6 4.0 15.3 10 6 5 15 15 15 3 Talin, middle domain FERM_f0 PF16511.5 KFR02123.1 - 9.9e-38 128.3 0.1 1.4e-34 118.3 0.0 3.3 3 0 0 3 3 3 2 N-terminal or F0 domain of Talin-head FERM FERM_M PF00373.18 KFR02123.1 - 4.6e-27 94.8 0.1 3.1e-26 92.1 0.0 2.6 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.10 KFR02123.1 - 3.8e-24 84.4 0.6 1.2e-21 76.4 0.7 3.2 2 0 0 2 2 2 1 FERM N-terminal domain IRS PF02174.17 KFR02123.1 - 0.00078 19.3 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 PTB domain (IRS-1 type) ACBP PF00887.19 KFR02123.1 - 0.0012 19.1 0.1 0.019 15.2 0.0 2.9 2 0 0 2 2 2 1 Acyl CoA binding protein DUF2605 PF10792.9 KFR02123.1 - 0.027 14.4 0.5 0.55 10.2 0.5 3.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) ubiquitin PF00240.23 KFR02123.1 - 0.14 11.9 0.3 26 4.6 0.0 3.7 3 0 0 3 3 3 0 Ubiquitin family C2 PF00168.30 KFR02125.1 - 1.1e-06 28.8 0.0 2.1e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain zf-C4 PF00105.18 KFR02126.1 - 4.2e-33 113.6 12.9 4.2e-33 113.6 12.9 2.3 3 0 0 3 3 3 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFR02126.1 - 3.1e-24 85.7 4.5 3.1e-24 85.7 4.5 1.9 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor NARG2_C PF10505.9 KFR02127.1 - 1.3e-77 260.1 0.6 2.6e-77 259.1 0.6 1.6 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus Annexin PF00191.20 KFR02128.1 - 2.5e-93 306.1 10.6 1.3e-26 92.4 0.5 4.1 4 0 0 4 4 4 4 Annexin Forkhead PF00250.18 KFR02129.1 - 1.1e-22 80.1 0.5 1.7e-22 79.4 0.5 1.3 1 0 0 1 1 1 1 Forkhead domain BNIP2 PF12496.8 KFR02130.1 - 1.1e-34 119.8 2.3 1.1e-34 119.8 2.3 1.5 2 0 0 2 2 2 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CRAL_TRIO_2 PF13716.6 KFR02130.1 - 7.8e-30 103.8 0.3 1.1e-29 103.4 0.3 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KFR02130.1 - 1e-08 35.1 0.0 1.5e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain TFIIA_gamma_N PF02268.16 KFR02131.1 - 7.9e-24 83.4 0.4 1.1e-23 82.9 0.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 KFR02131.1 - 1.7e-22 79.2 2.7 2.5e-22 78.7 2.7 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit OTU PF02338.19 KFR02132.1 - 8.3e-24 84.5 0.0 1.8e-23 83.4 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease UBA_4 PF14555.6 KFR02132.1 - 6e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 KFR02132.1 - 0.0046 16.6 0.0 0.0098 15.5 0.0 1.6 1 0 0 1 1 1 1 TAP C-terminal domain zf-C2H2 PF00096.26 KFR02133.1 - 7.3e-15 54.5 23.2 2.5e-05 24.5 0.5 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFR02133.1 - 7.7e-13 48.2 10.5 2.6e-07 30.7 2.4 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR02133.1 - 1.7e-08 34.6 20.4 0.0016 19.1 2.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFR02133.1 - 0.0008 20.0 8.6 0.24 12.1 0.4 3.2 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-met PF12874.7 KFR02133.1 - 0.023 15.1 9.9 1.4 9.4 0.3 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFR02133.1 - 0.046 14.0 7.2 0.15 12.4 6.3 2.1 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-Di19 PF05605.12 KFR02133.1 - 0.28 11.5 4.8 0.099 13.0 1.6 1.9 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding BIR PF00653.21 KFR02133.1 - 2.5 8.8 7.0 1.1 9.9 2.0 2.2 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain zf-C2H2_aberr PF17017.5 KFR02133.1 - 8.3 6.5 9.4 7.8 6.6 0.9 2.3 1 1 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 KFR02133.1 - 8.6 6.8 19.4 5.8 7.3 0.3 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding LSDAT_euk PF18139.1 KFR02134.1 - 1.3e-122 408.3 0.0 1.9e-122 407.8 0.0 1.2 1 0 0 1 1 1 1 SLOG in TRPM TRPM_tetra PF16519.5 KFR02134.1 - 2.3e-24 85.2 5.8 2.3e-24 85.2 5.8 1.9 2 0 0 2 2 2 1 Tetramerisation domain of TRPM Ion_trans PF00520.31 KFR02134.1 - 5.4e-20 71.7 16.1 8.8e-20 71.0 16.1 1.3 1 0 0 1 1 1 1 Ion transport protein LSDAT_prok PF18171.1 KFR02134.1 - 3.1e-17 62.5 0.0 5.6e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Myotub-related PF06602.14 KFR02135.1 - 2e-68 230.9 6.2 2.5e-56 191.2 3.0 2.1 1 1 1 2 2 2 2 Myotubularin-like phosphatase domain 3-PAP PF12578.8 KFR02135.1 - 2.7e-58 195.4 0.2 4.9e-58 194.6 0.2 1.4 1 0 0 1 1 1 1 Myotubularin-associated protein VRR_NUC PF08774.11 KFR02136.1 - 6.2e-26 90.6 0.0 1.5e-25 89.3 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain zf-WRNIP1_ubi PF18279.1 KFR02136.1 - 0.01 16.4 0.4 0.041 14.5 0.4 2.1 1 0 0 1 1 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain YabP PF07873.11 KFR02136.1 - 0.039 13.8 0.0 0.094 12.5 0.0 1.6 1 0 0 1 1 1 0 YabP family zf-TRAF PF02176.18 KFR02136.1 - 0.061 14.0 0.2 0.22 12.3 0.2 2.0 1 0 0 1 1 1 0 TRAF-type zinc finger zf_UBZ PF18439.1 KFR02136.1 - 0.063 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger PRP21_like_P PF12230.8 KFR02136.1 - 0.13 12.1 2.9 0.15 11.9 0.1 2.1 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein Mpp10 PF04006.12 KFR02137.1 - 1.6e-203 677.6 83.5 2.2e-203 677.1 83.5 1.2 1 0 0 1 1 1 1 Mpp10 protein Glyoxalase_4 PF13669.6 KFR02138.1 - 2.1e-21 76.2 0.0 2.7e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 KFR02138.1 - 3.3e-11 43.5 0.0 3.8e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KFR02138.1 - 1.8e-08 34.7 0.0 2.2e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KFR02138.1 - 0.0017 18.2 0.0 0.003 17.5 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain TPR_MalT PF17874.1 KFR02138.1 - 0.21 10.9 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 MalT-like TPR region PID PF00640.23 KFR02139.1 - 1.6e-51 174.0 2.3 1.6e-51 174.0 2.3 2.4 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.24 KFR02139.1 - 5.2e-27 94.0 10.9 1.7e-13 50.7 0.9 2.8 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 KFR02139.1 - 3.4e-15 55.6 2.3 9.6e-08 31.8 0.1 2.9 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 KFR02139.1 - 1.2e-05 25.5 0.1 0.0017 18.6 0.0 2.6 2 0 0 2 2 2 1 PDZ domain NRho PF16733.5 KFR02139.1 - 0.077 13.1 1.4 0.21 11.7 0.1 2.4 3 0 0 3 3 3 0 Rhomboid N-terminal domain CD20 PF04103.15 KFR02140.1 - 2.6e-12 47.1 12.0 5.2e-12 46.1 12.0 1.5 1 0 0 1 1 1 1 CD20-like family PDZ PF00595.24 KFR02141.1 - 1.1e-46 157.1 7.2 3.5e-15 56.1 0.1 3.5 3 0 0 3 3 3 3 PDZ domain ZU5 PF00791.20 KFR02141.1 - 2e-36 124.3 0.0 6e-36 122.7 0.0 1.9 1 0 0 1 1 1 1 ZU5 domain PDZ_6 PF17820.1 KFR02141.1 - 2.5e-24 84.9 2.4 3.7e-09 36.3 0.1 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 KFR02141.1 - 3.7e-16 59.2 3.8 8.3e-05 22.8 0.1 3.6 3 0 0 3 3 3 3 PDZ domain Guanylate_kin PF00625.21 KFR02141.1 - 1.6e-12 47.5 0.0 3e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.17 KFR02141.1 - 4.8e-11 42.2 0.1 1.2e-10 40.9 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFR02141.1 - 0.0024 17.4 0.1 0.021 14.4 0.0 2.6 2 0 0 2 2 2 1 SH3 domain RPOL_N PF14700.6 KFR02141.1 - 0.061 12.7 1.7 0.34 10.2 0.1 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal tRNA-synt_2b PF00587.25 KFR02142.1 - 1.6e-35 122.7 0.0 2.6e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KFR02142.1 - 9.4e-21 73.8 0.1 2.1e-20 72.6 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 KFR02142.1 - 8e-13 48.2 0.0 1.9e-12 47.0 0.0 1.7 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.14 KFR02142.1 - 9.6e-13 48.0 0.0 2.1e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TM2 PF05154.16 KFR02143.1 - 8.7e-15 54.8 7.9 1.4e-14 54.1 7.9 1.3 1 0 0 1 1 1 1 TM2 domain A_deaminase PF00962.22 KFR02144.1 - 5.5e-37 127.8 0.0 6.4e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 KFR02144.1 - 0.012 14.9 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase family La PF05383.17 KFR02145.1 - 6.9e-22 77.3 0.4 1.8e-21 75.9 0.2 1.8 2 0 0 2 2 2 1 La domain LRR_9 PF14580.6 KFR02146.1 - 3.2e-25 88.6 17.6 2.6e-15 56.4 4.2 3.9 2 1 1 3 3 3 3 Leucine-rich repeat LRR_4 PF12799.7 KFR02146.1 - 1.4e-21 76.2 39.5 1.6e-08 34.7 5.2 5.7 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFR02146.1 - 1.1e-12 47.5 42.4 4.2e-05 23.2 6.8 6.3 5 1 1 7 7 7 4 Leucine rich repeat LRR_3 PF07725.12 KFR02146.1 - 0.93 9.5 6.2 42 4.2 0.1 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat DUF2322 PF10084.9 KFR02146.1 - 0.96 9.5 3.7 8.5 6.5 0.3 3.5 3 1 2 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2322) ADAM_spacer1 PF05986.14 KFR02147.1 - 1.4e-36 124.9 0.0 2.1e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.19 KFR02147.1 - 3.5e-27 94.4 73.2 7.7e-08 32.4 4.9 6.9 5 1 1 6 6 6 6 Thrombospondin type 1 domain PLAC PF08686.11 KFR02147.1 - 4.2e-10 40.2 14.9 2.3e-09 37.8 14.9 2.5 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Neur_chan_LBD PF02931.23 KFR02148.1 - 2e-73 246.4 1.0 2.7e-73 246.0 1.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFR02148.1 - 1.4e-65 221.7 0.0 1.7e-65 221.4 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region SUR7 PF06687.12 KFR02148.1 - 0.087 12.4 2.5 0.099 12.3 0.0 2.2 2 0 0 2 2 2 0 SUR7/PalI family DUF2417 PF10329.9 KFR02148.1 - 1.4 8.3 5.0 1 8.7 2.7 1.8 2 0 0 2 2 2 0 Region of unknown function (DUF2417) tRNA_bind_3 PF17176.4 KFR02149.1 - 0.013 15.8 3.3 0.023 15.0 0.1 2.9 2 1 0 3 3 3 0 tRNA-binding domain Apolipoprotein PF01442.18 KFR02149.1 - 0.09 12.6 30.7 0.21 11.4 21.5 2.8 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KFR02149.1 - 0.41 10.7 22.6 1.3 9.1 0.8 4.1 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 KFR02149.1 - 0.98 9.6 36.3 1.4 9.1 0.4 3.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Myosin_head PF00063.21 KFR02150.1 - 8.3e-252 837.3 5.6 1e-251 836.9 5.6 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KFR02150.1 - 1.2e-54 184.9 1.3 2.4e-54 183.9 1.3 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 KFR02150.1 - 4.9e-17 61.3 0.3 1.8e-16 59.4 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFR02150.1 - 1.3e-15 57.0 0.1 3.9e-15 55.4 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFR02150.1 - 6.6e-12 44.9 0.0 1.5e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain AAA_16 PF13191.6 KFR02150.1 - 0.0064 16.9 0.0 0.043 14.2 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain IQ PF00612.27 KFR02150.1 - 0.0073 16.0 2.2 0.024 14.4 2.2 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif AAA_22 PF13401.6 KFR02150.1 - 0.049 13.9 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Microtub_bd PF16796.5 KFR02150.1 - 0.057 13.4 0.3 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 Microtubule binding Sigma54_activat PF00158.26 KFR02150.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 KFR02150.1 - 0.16 12.5 0.1 0.63 10.6 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Cyclin_N PF00134.23 KFR02151.1 - 8.4e-43 145.1 0.6 1.3e-41 141.4 0.1 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFR02151.1 - 3.8e-33 114.1 0.4 7.9e-33 113.1 0.2 1.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain RNF111_N PF15303.6 KFR02152.1 - 4.2e-127 423.7 24.2 4.2e-127 423.7 24.2 2.5 2 0 0 2 2 2 1 E3 ubiquitin-protein ligase Arkadia N-terminus zf-RING_2 PF13639.6 KFR02152.1 - 7.6e-13 48.6 6.8 7.6e-13 48.6 6.8 3.3 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFR02152.1 - 4.5e-09 36.0 6.6 4.5e-09 36.0 6.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFR02152.1 - 8.2e-08 31.9 2.6 8.2e-08 31.9 2.6 2.7 3 0 0 3 3 3 1 RING-like zinc finger zf-rbx1 PF12678.7 KFR02152.1 - 3.6e-07 30.4 4.1 3.6e-07 30.4 4.1 2.9 3 0 0 3 3 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KFR02152.1 - 9.6e-07 28.6 4.5 2.5e-06 27.2 4.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFR02152.1 - 1.8e-06 27.7 5.9 1.8e-06 27.7 5.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFR02152.1 - 3.3e-05 23.8 3.8 3.3e-05 23.8 3.8 2.5 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFR02152.1 - 0.00029 20.6 4.6 0.00029 20.6 4.6 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFR02152.1 - 0.068 13.2 5.8 0.14 12.2 3.9 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFR02152.1 - 0.1 12.2 6.1 0.068 12.8 3.4 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 KFR02152.1 - 0.56 10.4 6.6 2.2 8.5 6.5 2.2 1 1 0 1 1 1 0 RING-variant domain MINDY_DUB PF04424.13 KFR02153.1 - 3.9e-37 126.8 0.8 1.7e-36 124.8 0.0 2.1 2 0 0 2 2 2 1 MINDY deubiquitinase CCDC50_N PF15295.6 KFR02153.1 - 0.013 15.6 7.5 0.043 14.0 7.5 1.9 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus gpW PF02831.15 KFR02153.1 - 0.065 13.1 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 gpW Phage_ABA_S PF18066.1 KFR02153.1 - 0.13 13.0 0.1 0.53 11.0 0.0 2.0 2 0 0 2 2 2 0 Phage ABA sandwich domain Reprolysin_2 PF13574.6 KFR02154.1 - 4.9e-34 117.9 0.2 4.9e-34 117.9 0.2 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFR02154.1 - 3.5e-32 112.1 1.4 1.7e-31 109.9 0.2 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFR02154.1 - 1.2e-27 96.9 0.0 2.5e-27 95.8 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFR02154.1 - 5.3e-16 58.9 0.3 1.1e-15 57.8 0.3 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 KFR02154.1 - 1.9e-13 51.0 32.2 1.9e-13 51.0 32.2 3.6 3 1 0 3 3 3 1 Disintegrin Pep_M12B_propep PF01562.19 KFR02154.1 - 5e-13 49.5 1.0 1e-12 48.5 1.0 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 KFR02154.1 - 1.4e-07 31.6 1.1 1.2e-05 25.3 1.1 2.8 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Peptidase_M66 PF10462.9 KFR02154.1 - 0.024 13.6 0.2 0.048 12.6 0.2 1.4 1 0 0 1 1 1 0 Peptidase M66 UPF0370 PF13980.6 KFR02154.1 - 0.027 14.5 0.2 0.068 13.2 0.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) Lipase PF00151.19 KFR02155.1 - 8.2e-121 403.4 0.1 9.6e-121 403.2 0.1 1.0 1 0 0 1 1 1 1 Lipase PLAT PF01477.23 KFR02155.1 - 4.5e-18 65.9 1.1 9.1e-18 64.9 1.1 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain Abhydrolase_6 PF12697.7 KFR02155.1 - 7.7e-06 26.7 0.3 1e-05 26.2 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFR02155.1 - 0.0019 17.9 0.1 0.003 17.2 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold MIP PF00230.20 KFR02157.1 - 2.2e-51 174.8 14.1 2.8e-51 174.4 14.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein Aldedh PF00171.22 KFR02158.1 - 5.7e-79 265.8 0.0 6.4e-79 265.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_transf_29 PF00777.18 KFR02192.1 - 2.2e-77 260.1 0.1 2.4e-77 259.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) G_glu_transpept PF01019.21 KFR02192.1 - 0.13 11.0 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase Ndr PF03096.14 KFR02193.1 - 1.1e-124 414.8 0.0 1.3e-124 414.5 0.0 1.0 1 0 0 1 1 1 1 Ndr family Abhydrolase_1 PF00561.20 KFR02193.1 - 0.0038 16.9 0.0 0.21 11.2 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFR02193.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 IGFBP PF00219.18 KFR02194.1 - 1.1e-10 42.0 21.1 1.1e-10 42.0 21.1 5.1 4 3 0 4 4 4 1 Insulin-like growth factor binding protein Cys_knot PF00007.22 KFR02194.1 - 3.5e-09 36.9 8.5 3.5e-09 36.9 8.5 3.7 4 2 0 4 4 4 1 Cystine-knot domain VWC PF00093.18 KFR02194.1 - 1.5e-08 34.8 12.0 1.5e-08 34.8 12.0 5.3 4 3 0 4 4 4 1 von Willebrand factor type C domain TSP_1 PF00090.19 KFR02194.1 - 1.2e-05 25.4 5.9 1.2e-05 25.4 5.9 3.7 4 1 0 4 4 4 1 Thrombospondin type 1 domain SH2 PF00017.24 KFR02195.1 - 4.7e-21 74.7 0.1 1.1e-20 73.5 0.1 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFR02195.1 - 5.7e-07 29.1 0.0 1.1e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain HSBP1 PF06825.12 KFR02196.1 - 0.032 14.1 0.8 0.056 13.3 0.3 1.7 2 0 0 2 2 2 0 Heat shock factor binding protein 1 TMEM71 PF15121.6 KFR02197.1 - 4.2e-61 205.0 0.6 6.3e-61 204.4 0.6 1.2 1 0 0 1 1 1 1 TMEM71 protein family LRR_9 PF14580.6 KFR02198.1 - 5.9e-15 55.2 1.8 1.6e-14 53.7 1.8 1.8 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KFR02198.1 - 1.1e-09 38.4 14.3 1.4e-05 25.3 0.8 3.7 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFR02198.1 - 1.6e-05 24.5 5.3 5.6e-05 22.8 3.2 2.7 1 1 1 2 2 2 2 Leucine rich repeat KCNQ_channel PF03520.14 KFR02199.1 - 2.9e-82 275.1 0.3 4.6e-82 274.5 0.3 1.3 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel KCNQC3-Ank-G_bd PF11956.8 KFR02199.1 - 8.5e-40 135.2 1.7 1.9e-39 134.1 1.7 1.6 1 0 0 1 1 1 1 Ankyrin-G binding motif of KCNQ2-3 Ion_trans PF00520.31 KFR02199.1 - 1.5e-28 99.7 2.5 1.6e-28 99.6 1.2 1.6 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.16 KFR02199.1 - 7.1e-13 48.3 0.3 1.8e-12 47.0 0.3 1.6 1 0 0 1 1 1 1 Ion channel Lig_chan PF00060.26 KFR02199.1 - 0.00035 20.4 0.0 0.00083 19.2 0.0 1.6 1 0 0 1 1 1 1 Ligand-gated ion channel Phospholip_A2_1 PF00068.19 KFR02201.1 - 2.5e-52 176.1 39.8 3.4e-27 95.1 16.5 2.3 2 0 0 2 2 2 2 Phospholipase A2 DUF717 PF05338.12 KFR02201.1 - 0.03 14.4 0.0 0.09 12.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF717) Guanylate_cyc PF00211.20 KFR02204.1 - 4.2e-88 293.8 0.0 3.7e-58 196.2 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 KFR02204.1 - 1.1e-34 120.4 5.4 1.1e-34 120.4 5.4 2.4 2 0 0 2 2 2 1 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF1053 PF06327.14 KFR02204.1 - 2.6e-28 98.6 0.1 6.8e-28 97.3 0.1 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) TBK1_ULD PF18396.1 KFR02204.1 - 0.0061 16.5 0.2 0.016 15.1 0.2 1.6 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF1394 PF07159.12 KFR02206.1 - 1.5e-142 474.3 0.0 1.7e-142 474.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) V-ATPase_H_N PF03224.14 KFR02206.1 - 0.021 14.1 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H OSK PF17182.4 KFR02209.1 - 0.00041 19.7 0.0 0.00068 18.9 0.0 1.2 1 0 0 1 1 1 1 OSK domain LRAT PF04970.13 KFR02210.1 - 6.1e-14 52.4 0.4 9.1e-06 26.0 0.2 2.4 1 1 1 2 2 2 2 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 KFR02210.1 - 0.079 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 NlpC/P60 family MCM PF00493.23 KFR02255.1 - 1.2e-98 328.6 0.0 1.9e-98 328.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFR02255.1 - 8.2e-37 125.9 0.1 1.6e-36 124.9 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFR02255.1 - 3.9e-29 100.9 1.7 9.6e-29 99.7 1.7 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFR02255.1 - 2.3e-17 63.5 0.7 1.1e-16 61.3 0.7 2.2 1 0 0 1 1 1 1 MCM N-terminal domain MCM2_N PF12619.8 KFR02255.1 - 1.8e-15 57.5 18.8 1.8e-15 57.5 18.8 2.2 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.21 KFR02255.1 - 1.3e-08 34.5 0.0 5.3e-07 29.2 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KFR02255.1 - 4.4e-07 29.8 0.0 3.1e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFR02255.1 - 6.1e-07 29.5 0.0 2.6e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 KFR02255.1 - 0.0011 18.8 0.4 0.004 17.0 0.1 2.1 2 0 0 2 2 1 1 AAA lid domain Sigma54_activat PF00158.26 KFR02255.1 - 0.003 17.3 0.1 1.2 8.8 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA PF00004.29 KFR02255.1 - 0.0032 17.9 0.0 0.009 16.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 KFR02255.1 - 0.011 15.8 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.6 KFR02255.1 - 0.047 13.8 0.0 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF737 PF05300.11 KFR02256.1 - 8.6e-47 160.1 30.5 2.1e-44 152.3 30.5 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF737) CHCH PF06747.13 KFR02256.1 - 4e-06 26.8 3.6 7.7e-06 25.9 3.6 1.5 1 0 0 1 1 1 1 CHCH domain NDUF_B7 PF05676.13 KFR02256.1 - 0.0038 16.9 3.9 0.01 15.6 2.0 2.4 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Exonuc_VII_L PF02601.15 KFR02256.1 - 1.3 8.6 8.5 1.7 8.1 8.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1690 PF07956.11 KFR02256.1 - 3.6 8.0 23.8 2.1e+02 2.3 0.0 3.1 2 1 0 2 2 2 0 Protein of Unknown function (DUF1690) Sema PF01403.19 KFR02257.1 - 6.2e-68 229.5 0.0 7.2e-68 229.3 0.0 1.0 1 0 0 1 1 1 1 Sema domain Plexin_cytopl PF08337.12 KFR02258.1 - 2.9e-255 848.2 8.1 3.5e-255 847.9 8.1 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.24 KFR02258.1 - 2.7e-46 155.5 12.7 5.1e-13 48.9 0.1 5.7 5 0 0 5 5 5 4 IPT/TIG domain TIG_2 PF18020.1 KFR02258.1 - 5.4e-32 110.3 0.1 2.3e-31 108.2 0.1 2.2 1 0 0 1 1 1 1 TIG domain found in plexin TIG_plexin PF17960.1 KFR02258.1 - 3.1e-27 94.4 7.0 2.8e-22 78.5 0.0 5.7 7 0 0 7 7 7 2 TIG domain PSI PF01437.25 KFR02258.1 - 3.2e-21 75.6 53.7 2.3e-09 37.7 12.4 3.7 3 0 0 3 3 3 3 Plexin repeat PSI_integrin PF17205.3 KFR02258.1 - 1.6 8.5 48.4 0.02 14.7 11.4 3.8 3 0 0 3 3 3 0 Integrin plexin domain Pyr_redox_2 PF07992.14 KFR02260.1 - 4.5e-53 180.4 0.1 5.4e-53 180.1 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFR02260.1 - 1e-28 99.7 0.0 2.3e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFR02260.1 - 1.1e-16 61.2 2.9 7.6e-14 52.0 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFR02260.1 - 5.4e-13 48.9 0.5 3.2e-09 36.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFR02260.1 - 2.3e-07 30.3 0.1 1.1e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KFR02260.1 - 0.00026 20.4 0.3 0.14 11.4 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KFR02260.1 - 0.00066 18.5 0.4 0.0013 17.5 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KFR02260.1 - 0.0013 18.2 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFR02260.1 - 0.003 16.8 0.8 0.012 14.9 0.1 2.1 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 KFR02260.1 - 0.012 14.7 2.2 0.055 12.5 2.2 2.1 1 1 0 1 1 1 0 Glucose inhibited division protein A DAO PF01266.24 KFR02260.1 - 0.027 14.0 0.6 0.063 12.8 0.4 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFR02260.1 - 0.2 11.9 6.7 0.14 12.4 0.7 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Sulfotransfer_2 PF03567.14 KFR02261.1 - 1.1e-69 235.2 4.0 1.3e-69 235.0 4.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family DUF4543 PF15076.6 KFR02261.1 - 0.073 13.2 0.7 0.15 12.2 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) MgtE PF01769.16 KFR02262.1 - 5.1e-35 120.5 25.4 8.2e-23 81.1 7.7 3.3 4 0 0 4 4 4 2 Divalent cation transporter GNVR PF13807.6 KFR02262.1 - 1.8 8.5 4.1 0.45 10.5 0.4 2.0 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase zf-C2H2 PF00096.26 KFR02263.1 - 6.2e-15 54.7 20.5 3.2e-05 24.1 1.6 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFR02263.1 - 4.9e-13 48.8 20.0 4e-09 36.5 1.0 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR02263.1 - 1.1e-07 32.1 28.3 0.00037 21.1 2.1 4.2 5 0 0 5 5 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFR02263.1 - 2e-05 25.1 8.2 0.19 12.4 0.2 3.7 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2_9 PF16293.5 KFR02263.1 - 0.01 15.7 0.9 0.068 13.0 0.1 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-met PF12874.7 KFR02263.1 - 0.011 16.1 4.4 0.18 12.3 0.8 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF2225 PF09986.9 KFR02263.1 - 0.044 13.5 0.4 0.13 12.0 0.5 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-Di19 PF05605.12 KFR02263.1 - 0.7 10.2 6.8 0.3 11.4 2.0 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 KFR02263.1 - 1.4 9.3 9.6 0.19 12.1 4.8 2.1 2 1 0 2 2 2 0 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 KFR02263.1 - 1.4 8.9 4.4 0.51 10.3 0.5 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KFR02263.1 - 3.2 8.1 6.3 2.1 8.8 0.3 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding IBR PF01485.21 KFR02263.1 - 3.9 7.8 8.2 4.4 7.6 5.1 2.5 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-C2H2 PF00096.26 KFR02264.1 - 1.4e-13 50.5 38.5 0.00061 20.1 0.4 6.5 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR02264.1 - 1.7e-11 43.9 38.1 0.01 16.6 0.6 6.4 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFR02264.1 - 1.1e-06 28.8 32.0 0.011 16.1 0.1 5.7 5 1 1 6 6 6 3 Zinc-finger double domain zf-C2H2_aberr PF17017.5 KFR02264.1 - 5.1e-05 23.5 17.1 0.62 10.2 0.5 4.8 1 1 2 4 4 4 3 Aberrant zinc-finger zf-C2H2_8 PF15909.5 KFR02264.1 - 0.00024 21.3 15.8 0.026 14.8 1.9 4.0 1 1 3 4 4 4 3 C2H2-type zinc ribbon FOXP-CC PF16159.5 KFR02264.1 - 0.6 10.8 15.9 4.9 7.9 0.3 4.9 3 3 2 5 5 5 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KFR02264.1 - 0.61 10.2 23.1 2.1 8.5 1.9 5.3 5 0 0 5 5 5 0 C2H2-type zinc finger Laminin_N PF00055.17 KFR02265.1 - 3.3e-62 210.1 0.0 3.3e-62 210.1 0.0 2.2 2 1 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 KFR02265.1 - 2.2e-26 91.7 68.9 1.2e-09 38.1 10.0 6.5 5 1 1 6 6 6 4 Laminin EGF domain NTR PF01759.21 KFR02265.1 - 9.2e-23 80.1 0.3 8.5e-22 77.0 0.1 2.3 2 0 0 2 2 2 1 UNC-6/NTR/C345C module F5_F8_type_C PF00754.25 KFR02265.1 - 0.024 14.7 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 F5/8 type C domain CHCH PF06747.13 KFR02266.1 - 1.3e-07 31.6 2.8 2.3e-07 30.8 2.8 1.4 1 0 0 1 1 1 1 CHCH domain TMEM43 PF07787.12 KFR02267.1 - 7.7e-87 290.8 0.0 1.1e-86 290.3 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 43 BHD_3 PF10405.9 KFR02268.1 - 6.3e-26 90.6 0.0 1.4e-25 89.5 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 KFR02268.1 - 2.4e-22 79.2 0.8 2.4e-22 79.2 0.8 3.4 3 0 0 3 3 3 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 KFR02268.1 - 1.1e-16 60.4 0.1 3.3e-16 58.9 0.0 1.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KFR02268.1 - 1.7e-14 54.5 0.5 1.7e-14 54.5 0.5 5.1 5 1 0 5 5 5 1 Rad4 beta-hairpin domain 2 Nucleo_P87 PF07267.11 KFR02268.1 - 0.22 10.3 14.9 0.49 9.2 14.9 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 LSM PF01423.22 KFR02269.1 - 2.4e-20 72.0 0.2 3.1e-20 71.6 0.2 1.2 1 0 0 1 1 1 1 LSM domain vATP-synt_E PF01991.18 KFR02269.1 - 0.045 13.1 0.1 0.063 12.7 0.1 1.4 1 1 1 2 2 2 0 ATP synthase (E/31 kDa) subunit DUF150_C PF17384.2 KFR02269.1 - 0.064 13.4 0.2 0.11 12.7 0.2 1.5 1 1 0 1 1 1 0 RimP C-terminal SH3 domain Glutaredoxin PF00462.24 KFR02269.1 - 0.17 12.2 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin SNF PF00209.18 KFR02270.1 - 1.4e-240 799.4 37.2 1.7e-240 799.2 37.2 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family PDZ PF00595.24 KFR02271.1 - 1.2e-93 307.6 1.9 4.3e-13 49.4 0.1 7.2 7 0 0 7 7 7 7 PDZ domain PDZ_6 PF17820.1 KFR02271.1 - 2.2e-70 232.4 9.2 2e-12 46.8 0.1 7.3 7 0 0 7 7 7 7 PDZ domain PDZ_2 PF13180.6 KFR02271.1 - 4.4e-38 129.5 1.3 1.8e-05 25.0 0.0 7.4 7 0 0 7 7 7 7 PDZ domain Tricorn_PDZ PF14685.6 KFR02271.1 - 1.4e-10 40.9 2.0 0.092 12.7 0.0 6.6 6 0 0 6 6 6 2 Tricorn protease PDZ domain GRASP55_65 PF04495.14 KFR02271.1 - 5.4e-05 23.5 0.0 4.8 7.5 0.0 4.7 4 2 2 6 6 6 2 GRASP55/65 PDZ-like domain PDZ_4 PF17816.1 KFR02271.1 - 0.0086 16.5 0.9 12 6.3 0.0 4.7 6 0 0 6 6 6 1 PDZ domain EutA PF06277.11 KFR02271.1 - 0.056 12.3 0.2 0.41 9.4 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutA MoaE PF02391.17 KFR02271.1 - 0.19 12.0 0.1 21 5.4 0.0 3.0 3 0 0 3 3 3 0 MoaE protein DUF4078 PF13300.6 KFR02273.1 - 2.5e-27 95.0 11.0 2.5e-27 95.0 11.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) L51_S25_CI-B8 PF05047.16 KFR02274.1 - 0.056 13.4 0.0 0.47 10.4 0.0 2.3 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain T2SSF PF00482.23 KFR02275.1 - 0.019 14.9 0.9 0.22 11.5 0.1 2.7 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F FAP206 PF12018.8 KFR02275.1 - 0.3 10.5 5.4 6.1 6.3 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function DUF2730 PF10805.8 KFR02275.1 - 0.51 10.5 4.5 1.7 8.8 0.1 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF2730) CorA PF01544.18 KFR02275.1 - 1.2 8.4 8.2 2.5 7.4 0.9 2.4 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Plexin_cytopl PF08337.12 KFR02276.1 - 1e-232 773.8 0.0 1.4e-232 773.3 0.0 1.2 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain Sema PF01403.19 KFR02276.1 - 1.6e-58 198.5 0.0 2.4e-58 197.9 0.0 1.2 1 0 0 1 1 1 1 Sema domain TIG PF01833.24 KFR02276.1 - 3e-33 113.8 2.3 7.9e-11 41.9 1.0 6.7 6 1 0 6 6 6 4 IPT/TIG domain TIG_2 PF18020.1 KFR02276.1 - 1.2e-24 86.7 0.5 1.4e-22 80.1 0.3 3.2 3 0 0 3 3 3 1 TIG domain found in plexin TIG_plexin PF17960.1 KFR02276.1 - 2.4e-20 72.3 3.3 1.4e-19 69.8 0.0 3.5 4 0 0 4 4 4 1 TIG domain PSI PF01437.25 KFR02276.1 - 6.9e-18 64.9 45.5 1.6e-09 38.1 14.3 3.6 3 0 0 3 3 3 3 Plexin repeat Pkinase PF00069.25 KFR02277.1 - 5.4e-35 121.0 0.0 2e-34 119.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR02277.1 - 9.7e-13 48.0 0.0 4.8e-12 45.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFR02277.1 - 0.003 16.4 0.0 0.0044 15.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KFR02277.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.11 KFR02277.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase SET PF00856.28 KFR02279.1 - 2.1e-07 31.5 5.4 2.4e-07 31.3 0.1 3.3 3 1 0 3 3 3 1 SET domain L_HMGIC_fpl PF10242.9 KFR02280.1 - 7.5e-61 205.5 8.5 8.4e-61 205.3 8.5 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.20 KFR02280.1 - 8.5e-05 22.5 5.2 0.00011 22.1 5.2 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFR02280.1 - 0.00015 21.6 9.5 0.00015 21.6 9.5 1.6 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Atthog PF18800.1 KFR02280.1 - 0.0032 17.4 3.9 0.0039 17.1 3.9 1.2 1 0 0 1 1 1 1 Attenuator of Hedgehog SLATT_fungal PF18142.1 KFR02280.1 - 0.11 12.5 0.2 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Phage_holin_3_6 PF07332.11 KFR02280.1 - 3 7.9 9.0 4.2 7.4 5.7 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2721 PF11026.8 KFR02280.1 - 9 6.2 14.9 23 4.9 10.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Myotub-related PF06602.14 KFR02281.1 - 0.0002 20.4 0.4 0.00056 18.9 0.4 1.5 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 KFR02281.1 - 0.0005 20.1 0.0 0.00085 19.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KFR02281.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Copine PF07002.16 KFR02282.1 - 1.2e-86 289.7 0.0 1.6e-86 289.3 0.0 1.1 1 0 0 1 1 1 1 Copine C2 PF00168.30 KFR02282.1 - 2.9e-25 88.5 0.1 3.3e-12 46.6 0.0 2.2 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 KFR02282.1 - 6.6e-07 29.6 0.0 1.6e-06 28.4 0.0 1.6 2 0 0 2 2 2 1 vWA found in TerF C terminus VCBS PF13517.6 KFR02282.1 - 0.03 14.9 0.2 0.12 13.0 0.2 2.0 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Phenol_MetA_deg PF13557.6 KFR02282.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative MetA-pathway of phenol degradation zf-HC5HC2H_2 PF13832.6 KFR02283.1 - 2e-37 127.7 7.4 2e-37 127.7 7.4 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 KFR02283.1 - 1.1e-34 120.1 8.8 1.1e-34 120.1 8.8 3.2 3 1 0 3 3 3 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 KFR02283.1 - 7.7e-26 90.2 6.1 7.7e-26 90.2 6.1 3.3 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.25 KFR02283.1 - 1.7e-22 79.3 1.0 3.7e-22 78.2 1.0 1.6 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.17 KFR02283.1 - 1.7e-16 60.4 1.7 3.4e-16 59.4 0.0 2.5 2 0 0 2 2 2 1 PWWP domain PHD_2 PF13831.6 KFR02283.1 - 1.1e-14 53.7 3.2 1.1e-14 53.7 3.2 2.7 2 1 1 3 3 3 1 PHD-finger PHD PF00628.29 KFR02283.1 - 1.5e-08 34.4 27.0 3.5e-07 30.0 12.5 2.9 2 0 0 2 2 2 2 PHD-finger PGA2 PF07543.12 KFR02283.1 - 1.3 8.9 6.9 1.2 9.1 1.3 3.2 2 0 0 2 2 2 0 Protein trafficking PGA2 Pkinase PF00069.25 KFR02284.1 - 4.4e-44 150.8 0.1 4.6e-30 104.9 0.1 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFR02284.1 - 4.4e-17 62.2 0.0 6.7e-16 58.3 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KFR02284.1 - 0.00073 19.0 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFR02284.1 - 0.02 14.2 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KFR02284.1 - 0.022 13.6 0.0 0.039 12.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KFR02284.1 - 0.025 14.5 0.0 0.064 13.2 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KFR02284.1 - 0.039 13.6 0.1 0.077 12.6 0.1 1.4 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 KFR02284.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Ada3 PF10198.9 KFR02285.1 - 6.4e-27 94.3 12.5 6.1e-26 91.1 11.2 2.5 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 ARPC4 PF05856.12 KFR02286.1 - 8.4e-60 201.2 7.5 1.2e-44 151.9 3.9 2.0 1 1 0 2 2 2 2 ARP2/3 complex 20 kDa subunit (ARPC4) TTL PF03133.15 KFR02287.1 - 1.5e-64 217.9 0.0 3.4e-64 216.8 0.0 1.4 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KFR02287.1 - 0.16 11.2 0.0 2.2 7.4 0.0 2.3 2 0 0 2 2 2 0 YheC/D like ATP-grasp Jagunal PF07086.12 KFR02288.1 - 2.7e-43 148.2 7.1 3e-43 148.1 7.1 1.0 1 0 0 1 1 1 1 Jagunal, ER re-organisation during oogenesis DUF3810 PF12725.7 KFR02288.1 - 0.092 12.1 2.1 0.11 11.9 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) IHO1 PF15771.5 KFR02290.1 - 1.5e-23 83.4 3.6 1.7e-23 83.3 3.6 1.0 1 0 0 1 1 1 1 Interactor of HORMAD1 protein 1 Kelch_1 PF01344.25 KFR02291.1 - 2.5e-50 167.8 0.2 4.6e-09 35.7 0.0 7.9 8 0 0 8 8 8 6 Kelch motif Kelch_6 PF13964.6 KFR02291.1 - 3.6e-35 119.1 1.7 1.5e-05 25.1 0.0 7.4 3 3 4 7 7 7 6 Kelch motif Kelch_3 PF13415.6 KFR02291.1 - 4.4e-29 100.2 2.3 1.1e-05 25.5 0.0 7.1 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KFR02291.1 - 1e-25 89.5 0.0 9.4e-06 25.5 0.0 7.2 6 1 1 7 7 7 6 Galactose oxidase, central domain Kelch_2 PF07646.15 KFR02291.1 - 1.3e-19 69.3 0.1 0.0033 17.3 0.0 7.5 7 1 0 7 7 7 3 Kelch motif Kelch_5 PF13854.6 KFR02291.1 - 2.6e-12 46.4 0.4 0.0013 18.6 0.0 6.0 6 0 0 6 6 6 3 Kelch motif DUF1668 PF07893.13 KFR02291.1 - 0.0062 15.9 1.0 0.043 13.2 0.1 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF1668) HEAT_PBS PF03130.16 KFR02291.1 - 0.37 11.6 1.9 4.6 8.2 0.0 3.3 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat CCDC71L PF15374.6 KFR02293.1 - 5.9e-173 575.7 17.7 6.6e-173 575.5 17.7 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 71L SNF PF00209.18 KFR02294.1 - 4.3e-166 553.7 21.6 3.1e-127 425.4 11.0 2.1 2 0 0 2 2 2 2 Sodium:neurotransmitter symporter family tRNA-synt_1c PF00749.21 KFR02295.1 - 2.1e-113 378.4 0.0 2.7e-113 378.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KFR02295.1 - 3.8e-49 166.9 0.0 7.7e-49 165.9 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 KFR02295.1 - 9.7e-29 100.1 1.1 1.7e-28 99.4 1.1 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 tRNA_synt_1c_R1 PF04558.15 KFR02295.1 - 2.8e-25 89.2 0.0 5.5e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 DUF3504 PF12012.8 KFR02296.1 - 2.9e-62 209.4 1.5 2.9e-62 209.4 1.5 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF3504) CARD PF00619.21 KFR02296.1 - 0.0035 17.4 0.0 0.0097 15.9 0.0 1.8 1 0 0 1 1 1 1 Caspase recruitment domain PCNA_C PF02747.15 KFR02296.1 - 0.066 13.4 0.8 0.17 12.0 0.8 1.6 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, C-terminal domain IMPDH PF00478.25 KFR02297.1 - 1.5e-108 362.9 2.7 1.7e-108 362.7 2.7 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KFR02297.1 - 1.6e-13 50.9 0.8 3.3e-05 24.2 0.0 2.9 3 0 0 3 3 3 2 CBS domain FMN_dh PF01070.18 KFR02297.1 - 1.1e-10 41.0 0.4 1.7e-10 40.5 0.4 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 KFR02297.1 - 1.1e-08 34.8 0.5 2.1e-08 33.9 0.5 1.5 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 KFR02297.1 - 1.2e-06 28.1 0.9 0.00027 20.5 0.0 2.3 1 1 1 2 2 2 2 Histidine biosynthesis protein NanE PF04131.14 KFR02297.1 - 2.6e-05 23.5 0.2 5.4e-05 22.5 0.2 1.5 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.14 KFR02297.1 - 0.0004 19.8 2.6 0.001 18.4 1.6 2.0 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG Dus PF01207.17 KFR02297.1 - 0.0013 17.9 0.4 0.33 10.0 0.0 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) Glu_synthase PF01645.17 KFR02297.1 - 0.0015 17.7 0.9 0.0025 17.0 0.9 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase G3P_antiterm PF04309.12 KFR02297.1 - 0.013 14.9 0.5 0.62 9.5 0.1 2.5 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Aldolase PF01081.19 KFR02297.1 - 0.019 14.4 0.6 1.6 8.1 0.0 2.6 3 0 0 3 3 3 0 KDPG and KHG aldolase DUF561 PF04481.12 KFR02297.1 - 0.049 12.8 0.3 0.086 12.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF561) DHO_dh PF01180.21 KFR02297.1 - 0.18 11.0 3.4 0.12 11.5 0.3 2.0 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase DUF498 PF04430.14 KFR02298.1 - 6.3e-22 77.7 0.0 7.1e-22 77.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) DALR_1 PF05746.15 KFR02299.1 - 1.5e-20 73.6 0.0 2.5e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 DALR anticodon binding domain WD40 PF00400.32 KFR02300.1 - 6.6e-09 36.3 4.6 1.8 9.6 0.0 8.3 9 0 0 9 9 9 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR02300.1 - 0.00073 19.8 0.0 0.11 12.9 0.0 3.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nsp3_PL2pro PF12124.8 KFR02300.1 - 0.13 12.1 0.0 0.4 10.5 0.0 1.8 2 0 0 2 2 2 0 Coronavirus polyprotein cleavage domain 2OG-FeII_Oxy_3 PF13640.6 KFR02301.1 - 1.4e-14 54.7 0.1 3.5e-14 53.5 0.1 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily EF-hand_7 PF13499.6 KFR02301.1 - 7.9e-09 35.9 0.0 2.9e-08 34.0 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFR02301.1 - 8.3e-08 31.3 0.0 0.0048 16.3 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFR02301.1 - 3.9e-06 26.4 1.4 0.018 14.9 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KFR02301.1 - 2.2e-05 23.7 0.1 0.17 11.5 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFR02301.1 - 0.00021 21.1 0.0 0.11 12.3 0.0 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KFR02301.1 - 0.079 13.3 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain TruB_C PF09142.11 KFR02301.1 - 0.2 11.5 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal Fz PF01392.22 KFR02302.1 - 3e-27 95.4 4.5 3e-27 95.4 4.5 1.7 2 0 0 2 2 2 1 Fz domain IBR PF01485.21 KFR02303.1 - 1.7e-20 73.0 45.3 8.3e-13 48.4 6.4 3.8 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KFR02303.1 - 0.0012 18.6 6.2 0.0012 18.6 6.2 4.1 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFR02303.1 - 0.0018 18.1 9.8 0.0018 18.1 9.8 4.4 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFR02303.1 - 0.01 16.1 46.7 0.037 14.4 9.9 4.1 2 1 1 3 3 3 0 Ring finger domain zf-RING_UBOX PF13445.6 KFR02303.1 - 0.022 14.8 3.2 0.022 14.8 3.2 3.6 3 0 0 3 3 3 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFR02303.1 - 0.026 14.7 4.9 0.026 14.7 4.9 4.5 4 1 0 4 4 4 0 zinc finger of C3HC4-type, RING Mito_carr PF00153.27 KFR02304.1 - 5.2e-61 202.6 0.1 4.3e-24 84.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein cNMP_binding PF00027.29 KFR02306.1 - 3.8e-42 142.3 0.1 4.9e-22 77.8 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RNase_P_Rpp14 PF01900.19 KFR02307.1 - 3.9e-06 27.0 0.0 4.5e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family MaoC_dehydratas PF01575.19 KFR02308.1 - 7.4e-20 70.8 0.0 9.6e-20 70.4 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KFR02308.1 - 1.4e-06 28.4 0.0 2.7e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.22 KFR02308.1 - 0.00041 20.6 0.0 0.0012 19.1 0.0 1.9 1 1 0 1 1 1 1 Thioesterase superfamily PX PF00787.24 KFR02309.1 - 2.8e-16 59.5 0.0 2.8e-16 59.5 0.0 3.0 4 0 0 4 4 4 1 PX domain Pkinase PF00069.25 KFR02309.1 - 6e-10 38.9 0.2 1e-08 34.9 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR02309.1 - 8.2e-08 31.8 0.0 3.4e-06 26.6 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase WH2 PF02205.20 KFR02309.1 - 9.3e-08 31.7 0.0 1.7e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 WH2 motif Rrn6 PF10214.9 KFR02309.1 - 1.7 7.1 8.3 2.2 6.7 8.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Transket_pyr PF02779.24 KFR02310.1 - 7.5e-46 156.0 0.0 1.3e-45 155.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFR02310.1 - 3.4e-36 123.8 0.1 6e-36 123.1 0.1 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain BTB_2 PF02214.22 KFR02311.1 - 7.6e-22 77.5 0.1 2e-21 76.1 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 KFR02311.1 - 0.0004 20.5 0.0 0.00067 19.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain ACOX PF01756.19 KFR02312.1 - 2e-66 223.0 2.6 3.3e-64 215.8 0.7 2.3 2 0 0 2 2 2 2 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KFR02312.1 - 4.7e-28 98.2 0.0 9.8e-28 97.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KFR02312.1 - 3.7e-07 30.2 0.0 7.6e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KFR02312.1 - 4.3e-06 27.0 0.0 1.5e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF4313 PF14190.6 KFR02312.1 - 0.23 11.5 0.9 1.7 8.7 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4313) DUF1151 PF06625.11 KFR02313.1 - 1.5e-43 147.4 20.5 1.7e-43 147.1 20.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1151) TOPRIM_C PF16898.5 KFR02313.1 - 0.0081 16.4 0.8 0.01 16.1 0.8 1.1 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM Ala_racemase_N PF01168.20 KFR02313.1 - 0.072 12.7 0.3 0.084 12.5 0.3 1.0 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain ILEI PF15711.5 KFR02314.1 - 6.5e-27 93.8 0.1 9.9e-27 93.3 0.1 1.3 1 0 0 1 1 1 1 Interleukin-like EMT inducer DUF667 PF05018.13 KFR02315.1 - 4.5e-37 127.6 0.0 1.4e-36 125.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF667) OCRE PF17780.1 KFR02315.1 - 0.066 13.2 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 OCRE domain GA-like PF17573.2 KFR02315.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 GA-like domain HIT PF01230.23 KFR02317.1 - 1.7e-17 63.9 0.0 2.1e-17 63.7 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KFR02317.1 - 0.00015 22.2 0.0 0.00018 21.9 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF4570 PF15134.6 KFR02318.1 - 7.6e-44 148.2 3.8 9.5e-44 147.9 3.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4570) Angiomotin_C PF12240.8 KFR02318.1 - 0.016 14.8 3.8 0.022 14.3 3.8 1.2 1 0 0 1 1 1 0 Angiomotin C terminal Mis12 PF05859.12 KFR02318.1 - 0.032 14.3 0.5 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Mis12 protein MARVEL PF01284.23 KFR02319.1 - 1.2e-37 129.1 6.4 1.5e-37 128.8 6.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.12 KFR02319.1 - 0.001 18.8 1.2 0.0016 18.2 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF588) ECF_trnsprt PF12822.7 KFR02319.1 - 0.0098 16.0 0.3 0.031 14.4 0.3 1.7 1 1 0 1 1 1 1 ECF transporter, substrate-specific component Frizzled PF01534.17 KFR02319.1 - 0.033 13.2 3.9 0.041 12.9 0.2 2.0 1 1 0 2 2 2 0 Frizzled/Smoothened family membrane region DUF1129 PF06570.11 KFR02319.1 - 0.16 11.5 0.2 0.25 10.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF3278 PF11683.8 KFR02319.1 - 0.18 11.9 1.6 0.46 10.6 1.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3278) S_100 PF01023.19 KFR02320.1 - 0.00022 20.8 0.0 0.00037 20.1 0.0 1.4 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_8 PF13833.6 KFR02320.1 - 0.00055 19.7 0.0 0.013 15.4 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 KFR02320.1 - 0.0015 18.9 0.1 0.0027 18.1 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair Retrotran_gag_3 PF14244.6 KFR02320.1 - 0.14 11.9 0.1 0.37 10.6 0.0 1.8 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type THOC7 PF05615.13 KFR02321.1 - 9.6e-40 135.9 9.5 1.4e-39 135.4 0.8 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 UPF0193 PF05250.11 KFR02321.1 - 0.00093 19.1 4.0 0.00093 19.1 4.0 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0193) Spc7 PF08317.11 KFR02321.1 - 0.39 9.5 18.7 0.081 11.8 3.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein COG2 PF06148.11 KFR02321.1 - 0.39 10.8 11.1 0.12 12.4 1.6 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Peptidase_S46 PF10459.9 KFR02321.1 - 0.73 8.4 8.5 0.79 8.3 8.5 1.1 1 0 0 1 1 1 0 Peptidase S46 EP400_N PF15790.5 KFR02321.1 - 2 7.2 6.9 2.5 6.9 6.9 1.1 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal DUF16 PF01519.16 KFR02321.1 - 2.8 8.5 14.1 0.2 12.2 3.3 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF4407 PF14362.6 KFR02321.1 - 3.1 7.0 8.9 0.14 11.5 1.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 KFR02321.1 - 3.3 7.8 9.6 9.4 6.3 4.7 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) AATF-Che1 PF13339.6 KFR02321.1 - 3.8 8.2 13.9 2.1 9.0 6.4 2.2 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor V_ATPase_I PF01496.19 KFR02321.1 - 4.2 5.2 13.1 5.2 4.8 13.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Med9 PF07544.13 KFR02321.1 - 5.4 7.2 18.9 1.2 9.3 3.0 3.2 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 SCA7 PF08313.12 KFR02322.1 - 5.4e-26 90.3 1.9 5.4e-26 90.3 1.9 2.3 2 0 0 2 2 2 1 SCA7, zinc-binding domain OrsD PF12013.8 KFR02322.1 - 0.14 12.6 0.1 0.14 12.6 0.1 2.8 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D RPN7 PF10602.9 KFR02323.1 - 2.1e-62 209.9 2.6 3.1e-62 209.3 2.6 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KFR02323.1 - 3.4e-18 66.1 0.2 1.2e-17 64.3 0.0 2.0 2 0 0 2 2 2 1 PCI domain RPW8 PF05659.11 KFR02323.1 - 0.023 14.4 3.2 0.93 9.2 0.4 3.1 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF1732 PF08340.11 KFR02323.1 - 0.067 13.2 1.8 6.8 6.8 0.6 3.2 2 2 1 3 3 3 0 Domain of unknown function (DUF1732) LigB PF02900.18 KFR02323.1 - 0.27 10.3 0.7 0.67 9.0 0.5 1.5 1 1 1 2 2 2 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase GON PF08685.11 KFR02324.1 - 1.9e-81 272.7 1.2 1.9e-81 272.7 1.2 2.5 2 0 0 2 2 2 1 GON domain TSP_1 PF00090.19 KFR02324.1 - 1.6e-62 207.5 210.0 2.1e-07 31.0 7.6 17.2 17 1 0 17 17 16 14 Thrombospondin type 1 domain ADAM_spacer1 PF05986.14 KFR02324.1 - 1e-32 112.5 0.1 1.8e-32 111.8 0.1 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin PF01421.19 KFR02324.1 - 2.4e-27 96.2 0.4 5.4e-27 95.0 0.4 1.7 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 KFR02324.1 - 2.1e-19 69.8 12.2 4.4e-18 65.6 6.8 11.2 11 3 0 11 11 6 2 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 KFR02324.1 - 1.1e-15 58.3 1.9 2.4e-15 57.2 1.9 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFR02324.1 - 2.4e-10 41.0 0.3 5.7e-10 39.8 0.3 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFR02324.1 - 1e-09 38.6 0.5 2.6e-09 37.3 0.5 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 KFR02324.1 - 0.00032 20.9 0.1 0.00084 19.6 0.1 1.8 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_4 PF13583.6 KFR02324.1 - 0.0049 16.5 0.2 0.0095 15.6 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M78 PF06114.13 KFR02324.1 - 0.17 11.8 0.1 0.31 11.0 0.1 1.4 1 0 0 1 1 1 0 IrrE N-terminal-like domain PDZ PF00595.24 KFR02325.1 - 3.1e-66 219.7 5.4 5.1e-14 52.4 0.1 5.6 5 0 0 5 5 5 5 PDZ domain PDZ_6 PF17820.1 KFR02325.1 - 5.2e-50 167.1 9.9 4.7e-12 45.6 0.0 5.5 5 0 0 5 5 5 5 PDZ domain MAGI_u5 PF16666.5 KFR02325.1 - 5.6e-41 139.8 7.8 5.6e-41 139.8 7.8 4.4 5 0 0 5 5 5 1 Unstructured region on MAGI PDZ_2 PF13180.6 KFR02325.1 - 3.5e-30 104.2 0.0 2.6e-05 24.4 0.0 5.8 6 0 0 6 6 6 5 PDZ domain MAGI_u1 PF16663.5 KFR02325.1 - 3.2e-29 100.8 3.7 1.6e-28 98.6 3.7 2.3 1 0 0 1 1 1 1 Unstructured region on MAGI WW PF00397.26 KFR02325.1 - 1.2e-18 66.9 4.5 7.8e-10 38.7 0.4 2.7 2 0 0 2 2 2 2 WW domain Guanylate_kin PF00625.21 KFR02325.1 - 1.6e-09 37.8 0.0 3.1e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase Tricorn_PDZ PF14685.6 KFR02325.1 - 2e-08 34.1 6.3 0.11 12.5 0.0 5.1 5 0 0 5 5 5 3 Tricorn protease PDZ domain PDZ_4 PF17816.1 KFR02325.1 - 0.00056 20.3 0.0 11 6.5 0.0 3.9 4 0 0 4 4 4 1 PDZ domain Serglycin PF04360.12 KFR02325.1 - 0.062 13.2 0.3 0.17 11.9 0.3 1.7 1 0 0 1 1 1 0 Serglycin Mito_carr PF00153.27 KFR02326.1 - 1.9e-51 172.0 5.3 2.1e-21 75.6 0.6 4.0 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 KFR02326.1 - 0.03 13.5 1.7 0.4 9.8 0.0 2.6 2 1 1 3 3 3 0 Gammaproteobacterial serine protease LRR_8 PF13855.6 KFR02327.1 - 8.5e-89 291.3 71.9 8e-16 57.6 4.8 7.7 2 1 7 9 9 9 9 Leucine rich repeat I-set PF07679.16 KFR02327.1 - 2.8e-55 184.3 0.0 9.8e-23 80.0 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR02327.1 - 1.6e-49 166.4 0.0 4.1e-17 62.6 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain LRR_4 PF12799.7 KFR02327.1 - 7.9e-40 134.2 47.3 2.2e-05 24.7 0.6 9.5 4 2 5 10 10 10 10 Leucine Rich repeats (2 copies) Ig_2 PF13895.6 KFR02327.1 - 1.9e-35 121.0 0.0 1.2e-11 44.8 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFR02327.1 - 7.5e-33 112.6 0.1 4e-12 46.2 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain LRR_5 PF13306.6 KFR02327.1 - 4.2e-30 104.3 0.0 3.1e-09 36.9 0.0 4.0 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFR02327.1 - 1.6e-18 66.9 7.0 0.00015 21.3 0.0 5.4 1 1 4 5 5 5 5 Leucine-rich repeat V-set PF07686.17 KFR02327.1 - 1.6e-17 63.7 2.8 0.00042 20.5 0.0 5.8 3 3 0 3 3 3 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFR02327.1 - 1.3e-10 41.2 0.0 0.00053 20.0 0.0 3.7 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain LRR_1 PF00560.33 KFR02327.1 - 1.3e-09 37.2 34.8 7.9 7.5 0.1 14.3 14 1 1 15 15 15 0 Leucine Rich Repeat Ig_5 PF16681.5 KFR02327.1 - 5e-08 33.2 0.0 0.12 12.8 0.0 4.0 3 1 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFR02327.1 - 8.9e-06 25.2 0.0 1.7 8.2 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFR02327.1 - 1.6e-05 24.9 1.7 0.66 10.1 0.0 4.1 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain C1-set PF07654.15 KFR02327.1 - 0.00092 19.5 0.0 0.13 12.7 0.0 3.2 3 0 0 3 3 3 1 Immunoglobulin C1-set domain LRRCT PF01463.24 KFR02327.1 - 0.0014 19.0 0.0 0.0061 17.0 0.0 2.2 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain Ig_4 PF16680.5 KFR02327.1 - 0.0023 18.2 0.0 0.32 11.3 0.0 3.7 3 1 1 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 KFR02327.1 - 0.0034 17.4 0.0 2.9 8.0 0.0 3.1 3 0 0 3 3 3 1 C17orf99 Ig domain Receptor_2B4 PF11465.8 KFR02327.1 - 0.034 14.3 0.0 1.4 9.2 0.0 3.0 3 0 0 3 3 3 0 Natural killer cell receptor 2B4 DUF2201 PF09967.9 KFR02327.1 - 0.042 14.0 0.1 0.16 12.2 0.0 2.0 2 0 0 2 2 1 0 VWA-like domain (DUF2201) C2-set PF05790.15 KFR02327.1 - 0.044 14.0 0.0 18 5.6 0.0 3.4 3 0 0 3 3 3 0 Immunoglobulin C2-set domain LRR_6 PF13516.6 KFR02327.1 - 0.3 11.3 51.4 0.31 11.2 0.1 13.2 15 0 0 15 15 15 0 Leucine Rich repeat TPKR_C2 PF16920.5 KFR02327.1 - 5.4 7.2 6.6 32 4.7 2.9 3.3 3 0 0 3 3 2 0 Tyrosine-protein kinase receptor C2 Ig-like domain BACK PF07707.15 KFR02328.1 - 6e-32 109.8 1.4 5.2e-31 106.8 0.4 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_1 PF01344.25 KFR02328.1 - 1.1e-29 101.7 10.7 8e-11 41.3 0.6 5.5 5 0 0 5 5 5 4 Kelch motif BTB PF00651.31 KFR02328.1 - 1.5e-28 99.2 0.3 3.5e-28 98.1 0.3 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.6 KFR02328.1 - 6.6e-22 77.0 5.9 6.3e-05 23.1 0.0 5.9 4 2 1 5 5 5 5 Kelch motif Kelch_2 PF07646.15 KFR02328.1 - 3.7e-13 48.9 5.2 4.7e-06 26.4 0.2 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 KFR02328.1 - 9.4e-11 41.6 0.5 0.0066 16.4 0.0 4.4 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KFR02328.1 - 8e-09 35.6 1.8 0.013 15.8 0.0 4.5 5 0 0 5 5 5 2 Galactose oxidase, central domain DUF3342 PF11822.8 KFR02328.1 - 0.0077 16.4 1.2 0.047 13.9 0.0 2.7 3 1 0 3 3 3 1 Domain of unknown function (DUF3342) Kelch_5 PF13854.6 KFR02328.1 - 0.022 14.8 4.0 40 4.4 0.0 4.3 4 0 0 4 4 4 0 Kelch motif DUF4262 PF14081.6 KFR02328.1 - 0.087 13.0 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4262) MFS_1 PF07690.16 KFR02329.1 - 5.8e-44 150.5 26.8 1.1e-37 129.8 28.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFR02329.1 - 4.6e-08 32.3 3.3 0.0097 14.8 0.0 3.8 1 1 1 3 3 3 3 MFS_1 like family ATP-grasp_2 PF08442.10 KFR02330.1 - 6.7e-77 257.6 1.8 1.2e-76 256.8 1.4 1.6 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KFR02330.1 - 2.3e-28 98.9 0.2 5e-28 97.9 0.2 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KFR02330.1 - 3.6e-10 39.7 0.6 7.2e-10 38.7 0.1 1.6 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 KFR02330.1 - 0.00096 19.0 0.1 0.0022 17.8 0.1 1.6 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TAFA PF12020.8 KFR02331.1 - 1e-44 150.9 11.7 1.1e-44 150.7 11.7 1.0 1 0 0 1 1 1 1 TAFA family amfpi-1 PF12190.8 KFR02331.1 - 0.15 12.7 6.0 2.4 8.8 0.1 2.2 1 1 1 2 2 2 0 Fungal protease inhibitor EGF PF00008.27 KFR02331.1 - 6.8 7.1 14.5 0.7 10.3 0.7 3.4 2 1 0 2 2 2 0 EGF-like domain TAFA PF12020.8 KFR02332.1 - 8.5e-48 160.7 11.8 9.9e-48 160.5 11.8 1.0 1 0 0 1 1 1 1 TAFA family DUF563 PF04577.14 KFR02333.1 - 3.6e-28 99.1 0.6 6.5e-28 98.3 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) TMF_TATA_bd PF12325.8 KFR02334.1 - 1.4e-32 112.3 11.5 1.4e-32 112.3 11.5 8.1 2 1 5 7 7 7 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KFR02334.1 - 2.1e-19 69.3 25.6 2.1e-19 69.3 25.6 11.1 7 3 4 12 12 12 3 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 KFR02334.1 - 0.0055 17.3 4.3 0.0055 17.3 4.3 10.6 4 3 4 8 8 8 2 SlyX ThiF PF00899.21 KFR02335.1 - 4.4e-68 229.3 0.0 6.6e-68 228.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KFR02335.1 - 1.3e-24 86.2 0.3 1.9e-24 85.6 0.3 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 KFR02335.1 - 0.00075 19.6 0.0 0.0021 18.1 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UAE_UbL PF14732.6 KFR02335.1 - 0.00076 20.0 0.0 0.0015 19.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Pyr_redox PF00070.27 KFR02335.1 - 0.084 13.5 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PRA1 PF03208.19 KFR02336.1 - 9.9e-15 54.4 3.7 1.2e-14 54.2 3.7 1.0 1 0 0 1 1 1 1 PRA1 family protein Halogen_Hydrol PF10112.9 KFR02336.1 - 0.046 13.7 0.3 0.099 12.7 0.1 1.6 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein PsbX PF06596.11 KFR02336.1 - 0.064 13.3 1.1 0.11 12.5 0.1 1.9 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) LapA_dom PF06305.11 KFR02336.1 - 0.11 12.3 2.0 9.2 6.2 0.1 2.5 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF3487 PF11990.8 KFR02336.1 - 0.9 9.4 4.8 0.96 9.4 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3487) DUF3413 PF11893.8 KFR02336.1 - 8 5.6 9.3 8.7 5.4 6.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3413) DUF3338 PF11819.8 KFR02337.1 - 8.9e-54 181.2 8.2 8.9e-54 181.2 8.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3338) FERM_C PF09380.10 KFR02337.1 - 5.1e-23 81.3 0.5 1.9e-22 79.5 0.5 2.1 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 KFR02337.1 - 2.6e-20 73.0 1.7 2.7e-19 69.7 0.0 2.8 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.10 KFR02337.1 - 1.7e-11 43.9 0.5 4.3e-11 42.6 0.5 1.7 1 0 0 1 1 1 1 FERM N-terminal domain T2SSG PF08334.11 KFR02337.1 - 0.074 13.1 0.1 0.26 11.4 0.1 1.9 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G zf-C4pol PF14260.6 KFR02337.1 - 4 8.0 4.8 1.3 9.6 0.5 2.3 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta MITF_TFEB_C_3_N PF15951.5 KFR02338.1 - 6.7e-38 130.7 16.5 6.7e-38 130.7 16.5 2.8 2 1 0 2 2 2 1 MITF/TFEB/TFEC/TFE3 N-terminus DUF3371 PF11851.8 KFR02338.1 - 2.4e-37 128.9 0.9 2.4e-37 128.9 0.9 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF3371) HLH PF00010.26 KFR02338.1 - 1.7e-16 59.9 0.6 1.7e-16 59.9 0.6 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain TFIIA PF03153.13 KFR02338.1 - 1.1 9.2 10.2 2.2 8.2 10.3 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribophorin_I PF04597.14 KFR02338.1 - 1.7 7.7 4.4 3 6.9 4.4 1.4 1 0 0 1 1 1 0 Ribophorin I DHQ_synthase PF01761.20 KFR02339.1 - 3.1e-57 193.7 0.0 3.9e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 KFR02339.1 - 1.2e-15 57.9 0.0 5.6e-15 55.7 0.0 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 KFR02339.1 - 2e-05 23.6 0.0 3.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase SwrA PF17423.2 KFR02339.1 - 0.042 13.8 0.1 0.076 13.0 0.1 1.3 1 0 0 1 1 1 0 Swarming motility protein MDFI PF15316.6 KFR02340.1 - 5e-47 160.2 22.3 5e-47 160.2 22.3 1.3 1 1 0 1 1 1 1 MyoD family inhibitor FOXP-CC PF16159.5 KFR02343.1 - 2.6e-34 117.7 5.3 2.6e-34 117.7 5.3 4.7 5 1 1 6 6 6 1 FOXP coiled-coil domain Forkhead PF00250.18 KFR02343.1 - 4e-28 97.5 0.1 9.1e-28 96.4 0.1 1.6 1 0 0 1 1 1 1 Forkhead domain Zap1_zf2 PF18217.1 KFR02343.1 - 0.099 12.7 0.6 0.19 11.8 0.6 1.5 1 0 0 1 1 1 0 Zap1 zinc finger 2 Auxin_repressed PF05564.12 KFR02343.1 - 4.5 8.0 8.1 2 9.1 2.5 3.0 3 0 0 3 3 3 0 Dormancy/auxin associated protein IF4E PF01652.18 KFR02344.1 - 2.1e-37 128.4 0.0 2.5e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E 7tm_1 PF00001.21 KFR02345.1 - 7e-31 107.5 10.5 8.4e-31 107.2 10.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) UPF0114 PF03350.16 KFR02345.1 - 1.8 8.8 6.9 0.88 9.8 3.7 2.0 1 1 0 2 2 2 0 Uncharacterized protein family, UPF0114 Prokineticin PF06607.11 KFR02346.1 - 7.9e-40 135.1 9.8 8.6e-40 135.0 9.8 1.0 1 0 0 1 1 1 1 Prokineticin MIT_LIKE_ACTX PF17556.2 KFR02346.1 - 0.00059 20.4 8.2 0.00078 20.0 8.2 1.2 1 0 0 1 1 1 1 MIT-like atracotoxin family YAF2_RYBP PF17219.3 KFR02348.1 - 1.4e-20 72.5 1.2 3.2e-20 71.4 1.2 1.6 1 0 0 1 1 1 1 Yaf2/RYBP C-terminal binding motif zf-RanBP PF00641.18 KFR02348.1 - 1.8e-08 33.5 2.4 3.6e-08 32.6 2.4 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others C1_2 PF03107.16 KFR02348.1 - 0.11 12.9 1.0 0.21 12.0 1.0 1.4 1 0 0 1 1 1 0 C1 domain SOG2 PF10428.9 KFR02348.1 - 3.9 6.6 21.0 5.6 6.1 21.0 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein SHQ1 PF04925.15 KFR02349.1 - 1.2e-68 230.1 2.6 1.8e-68 229.5 2.6 1.3 1 0 0 1 1 1 1 SHQ1 protein V_ATPase_I PF01496.19 KFR02349.1 - 0.055 11.4 1.9 0.09 10.7 1.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TLP-20 PF06088.11 KFR02349.1 - 0.24 11.3 3.4 0.076 12.9 0.3 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Glyco_transf_8 PF01501.20 KFR02350.1 - 1.8e-12 47.4 0.0 3.2e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KFR02350.1 - 0.00039 19.9 0.5 0.00051 19.5 0.5 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 PPP4R2 PF09184.11 KFR02351.1 - 5.2e-76 256.0 11.4 5.2e-76 256.0 11.4 2.4 1 1 1 2 2 2 1 PPP4R2 PDZ PF00595.24 KFR02352.1 - 2.9e-19 69.2 1.3 3e-14 53.1 0.1 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFR02352.1 - 9.3e-15 54.2 1.0 3.9e-12 45.8 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFR02352.1 - 1.6e-06 28.3 0.4 8.3e-06 26.0 0.1 2.2 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 KFR02352.1 - 0.014 15.4 0.0 0.035 14.1 0.0 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain zf-C3HC4_2 PF13923.6 KFR02353.1 - 1.1e-09 38.0 7.7 1.1e-09 38.0 7.7 2.2 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) PDZ PF00595.24 KFR02353.1 - 1.1e-07 32.0 0.3 1.9e-07 31.3 0.3 1.3 1 0 0 1 1 1 1 PDZ domain zf-RING_UBOX PF13445.6 KFR02353.1 - 1.7e-07 31.1 6.4 8.3e-07 28.9 6.4 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFR02353.1 - 2.1e-07 30.7 6.2 2.1e-07 30.7 6.2 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFR02353.1 - 3.5e-06 26.8 7.2 1e-05 25.3 7.2 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFR02353.1 - 3.9e-06 26.6 5.3 3.9e-06 26.6 5.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFR02353.1 - 4.5e-06 26.9 7.6 4.5e-06 26.9 7.6 2.8 2 1 0 2 2 1 1 Ring finger domain Sina PF03145.16 KFR02353.1 - 5.6e-06 26.4 1.9 5.6e-06 26.4 1.9 1.7 1 1 1 2 2 2 1 Seven in absentia protein family zf-RING_5 PF14634.6 KFR02353.1 - 1.6e-05 24.8 6.3 1.6e-05 24.8 6.3 2.3 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFR02353.1 - 3.5e-05 23.9 7.5 3.5e-05 23.9 7.5 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING U-box PF04564.15 KFR02353.1 - 0.0071 16.5 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 U-box domain zf-rbx1 PF12678.7 KFR02353.1 - 0.0073 16.6 5.4 0.0073 16.6 5.4 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-TRAF PF02176.18 KFR02353.1 - 0.015 16.0 16.2 0.018 15.7 9.9 2.9 1 1 1 2 2 2 0 TRAF-type zinc finger PDZ_2 PF13180.6 KFR02353.1 - 0.017 15.5 0.0 0.027 14.8 0.0 1.3 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 KFR02353.1 - 0.075 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 PDZ domain I-set PF07679.16 KFR02354.1 - 5e-70 231.6 0.0 2e-16 59.8 0.0 6.4 6 0 0 6 6 6 5 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR02354.1 - 2.7e-65 216.9 8.4 1.3e-12 48.1 0.0 6.9 8 0 0 8 8 8 5 Immunoglobulin domain fn3 PF00041.21 KFR02354.1 - 6.9e-45 151.3 20.3 3.5e-15 56.1 1.9 4.4 4 0 0 4 4 4 4 Fibronectin type III domain Ig_2 PF13895.6 KFR02354.1 - 1.6e-43 146.9 0.3 8.8e-10 38.8 0.0 5.5 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 KFR02354.1 - 1.9e-43 146.6 1.2 2.7e-08 33.9 0.0 7.1 6 1 1 7 7 7 5 Immunoglobulin domain V-set PF07686.17 KFR02354.1 - 2.9e-27 95.0 13.0 0.0055 16.9 0.0 10.5 7 5 1 8 8 8 6 Immunoglobulin V-set domain Ig_5 PF16681.5 KFR02354.1 - 1.7e-11 44.4 0.0 0.083 13.3 0.0 6.2 6 0 0 6 6 6 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFR02354.1 - 4.5e-10 38.9 0.0 0.67 9.6 0.0 5.4 5 0 0 5 5 5 3 Immunoglobulin domain Tissue_fac PF01108.17 KFR02354.1 - 6.9e-07 29.1 3.5 5.7e-05 22.9 0.4 3.0 3 0 0 3 3 3 1 Tissue factor Izumo-Ig PF16706.5 KFR02354.1 - 3.9e-06 26.8 0.1 7.5 6.7 0.0 5.5 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain Interfer-bind PF09294.10 KFR02354.1 - 0.00033 20.9 0.2 5.2 7.4 0.0 3.4 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III C2-set_2 PF08205.12 KFR02354.1 - 0.00067 19.7 6.9 2.2 8.4 0.0 5.1 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFR02354.1 - 0.0014 19.2 12.6 0.11 13.0 0.7 3.8 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Egh16-like PF11327.8 KFR02354.1 - 0.019 15.4 0.0 0.085 13.3 0.0 2.2 1 0 0 1 1 1 0 Egh16-like virulence factor DUF4998 PF16389.5 KFR02354.1 - 0.13 11.8 1.1 1.1 8.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function Big_4 PF07532.11 KFR02354.1 - 0.14 11.9 6.5 2.7 7.8 0.1 4.0 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 4) Ig_3 PF13927.6 KFR02355.1 - 9.6e-71 234.4 1.2 1.5e-12 48.0 0.0 7.3 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 KFR02355.1 - 1.2e-68 227.2 0.4 1.3e-12 47.6 0.0 7.1 8 0 0 8 8 6 6 Immunoglobulin I-set domain fn3 PF00041.21 KFR02355.1 - 1.3e-52 176.1 7.1 1.5e-12 47.7 0.0 5.6 5 0 0 5 5 5 5 Fibronectin type III domain Ig_2 PF13895.6 KFR02355.1 - 5e-46 154.9 0.4 7.6e-09 35.8 0.0 6.8 7 0 0 7 7 6 6 Immunoglobulin domain ig PF00047.25 KFR02355.1 - 4.4e-42 142.2 1.2 1.8e-06 28.0 0.0 7.1 7 0 0 7 7 7 6 Immunoglobulin domain Bravo_FIGEY PF13882.6 KFR02355.1 - 1.1e-29 103.6 3.9 2.3e-29 102.6 3.9 1.6 1 0 0 1 1 1 1 Bravo-like intracellular region V-set PF07686.17 KFR02355.1 - 1.4e-20 73.5 5.4 0.00087 19.4 0.0 8.7 6 4 2 8 8 8 4 Immunoglobulin V-set domain Ig_4 PF16680.5 KFR02355.1 - 1.2e-10 41.5 0.0 0.87 9.9 0.0 5.8 6 0 0 6 6 6 3 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFR02355.1 - 1e-08 35.1 0.2 0.16 12.1 0.0 5.9 6 0 0 6 6 6 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFR02355.1 - 4.7e-08 32.5 0.0 0.0043 16.6 0.0 4.4 5 0 0 5 5 5 2 Immunoglobulin domain C2-set PF05790.15 KFR02355.1 - 0.0003 20.9 0.1 16 5.7 0.0 4.3 4 0 0 4 4 4 0 Immunoglobulin C2-set domain Izumo-Ig PF16706.5 KFR02355.1 - 0.00059 19.9 0.0 21 5.3 0.0 5.0 5 0 0 5 5 5 0 Izumo-like Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFR02355.1 - 0.00074 20.0 1.7 49 4.6 0.0 4.8 3 1 0 4 4 4 0 Purple acid Phosphatase, N-terminal domain Receptor_2B4 PF11465.8 KFR02355.1 - 0.0012 19.1 0.7 8.5 6.6 0.0 4.3 3 1 1 4 4 4 1 Natural killer cell receptor 2B4 Ig_C17orf99 PF17736.1 KFR02355.1 - 0.0064 16.5 0.5 43 4.2 0.0 4.8 6 0 0 6 6 5 0 C17orf99 Ig domain fn3_2 PF16893.5 KFR02355.1 - 0.014 15.5 0.0 0.17 12.1 0.0 2.8 3 0 0 3 3 2 0 Fibronectin type III domain Ig_3 PF13927.6 KFR02356.1 - 1.3e-79 262.9 12.3 6.8e-16 58.6 0.1 7.5 7 0 0 7 7 7 6 Immunoglobulin domain I-set PF07679.16 KFR02356.1 - 2.5e-77 255.0 0.0 2.7e-14 53.0 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin I-set domain ig PF00047.25 KFR02356.1 - 8.9e-54 179.6 6.6 4.4e-10 39.6 0.0 7.0 7 0 0 7 7 7 6 Immunoglobulin domain Ig_2 PF13895.6 KFR02356.1 - 5.3e-53 177.3 10.5 2.2e-09 37.5 0.0 7.5 7 0 0 7 7 7 6 Immunoglobulin domain fn3 PF00041.21 KFR02356.1 - 1.4e-34 118.3 15.4 2.4e-13 50.3 1.3 4.8 5 0 0 5 5 4 4 Fibronectin type III domain V-set PF07686.17 KFR02356.1 - 2.7e-34 117.6 9.2 5.6e-05 23.3 0.0 10.8 7 4 2 9 9 9 6 Immunoglobulin V-set domain Ig_6 PF18452.1 KFR02356.1 - 1.1e-13 50.4 0.0 0.3 10.7 0.0 6.3 6 0 0 6 6 6 4 Immunoglobulin domain Ig_5 PF16681.5 KFR02356.1 - 1.3e-11 44.7 0.2 0.54 10.7 0.0 6.8 7 0 0 7 7 7 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFR02356.1 - 1.7e-09 37.6 0.0 6 7.0 0.0 6.0 6 0 0 6 6 6 3 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 KFR02356.1 - 5.1e-09 36.3 0.2 0.62 10.4 0.0 6.1 6 0 0 6 6 6 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFR02356.1 - 3.5e-07 30.2 2.2 0.73 9.9 0.1 5.5 6 0 0 6 6 5 2 CD80-like C2-set immunoglobulin domain Tissue_fac PF01108.17 KFR02356.1 - 8.5e-06 25.6 1.6 0.0076 16.1 0.1 3.1 2 0 0 2 2 2 2 Tissue factor Pur_ac_phosph_N PF16656.5 KFR02356.1 - 0.00012 22.5 2.5 0.072 13.7 0.2 3.3 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFR02356.1 - 0.00021 21.6 0.8 2.8 8.3 0.0 4.3 5 0 0 5 5 5 1 Interferon-alpha/beta receptor, fibronectin type III V-set_CD47 PF08204.11 KFR02356.1 - 0.0005 20.1 8.5 0.47 10.4 0.0 5.2 4 1 1 5 5 5 1 CD47 immunoglobulin-like domain C2-set PF05790.15 KFR02356.1 - 0.0015 18.7 0.0 31 4.9 0.0 5.6 5 1 1 6 6 5 0 Immunoglobulin C2-set domain fn3_4 PF16794.5 KFR02356.1 - 0.0076 16.2 1.4 0.25 11.3 0.2 3.2 3 0 0 3 3 3 1 Fibronectin-III type domain Adeno_E3_CR1 PF02440.15 KFR02356.1 - 0.58 10.0 4.0 72 3.3 0.0 4.4 5 0 0 5 5 5 0 Adenovirus E3 region protein CR1 Ig_3 PF13927.6 KFR02357.1 - 5.1e-78 257.7 10.0 1.2e-14 54.6 0.0 7.4 8 0 0 8 8 7 6 Immunoglobulin domain I-set PF07679.16 KFR02357.1 - 1.3e-74 246.3 0.0 1.7e-14 53.7 0.0 6.8 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.6 KFR02357.1 - 3.5e-53 177.9 0.0 6.5e-08 32.8 0.0 6.7 5 1 1 6 6 6 6 Immunoglobulin domain ig PF00047.25 KFR02357.1 - 1.7e-51 172.3 4.9 2.1e-11 43.8 0.0 7.1 7 0 0 7 7 7 6 Immunoglobulin domain fn3 PF00041.21 KFR02357.1 - 1.5e-41 140.6 12.7 1e-14 54.6 0.1 4.5 4 0 0 4 4 4 4 Fibronectin type III domain V-set PF07686.17 KFR02357.1 - 3.7e-32 110.7 7.1 3.5e-05 23.9 0.2 11.1 7 4 1 8 8 8 5 Immunoglobulin V-set domain Ig_6 PF18452.1 KFR02357.1 - 1.4e-17 63.0 0.0 0.11 12.1 0.0 6.4 6 0 0 6 6 6 5 Immunoglobulin domain Ig_5 PF16681.5 KFR02357.1 - 8.4e-12 45.3 0.0 0.022 15.2 0.0 7.2 7 1 0 7 7 7 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 KFR02357.1 - 3.6e-10 39.8 0.0 0.15 12.1 0.0 5.6 5 0 0 5 5 5 2 C17orf99 Ig domain Izumo-Ig PF16706.5 KFR02357.1 - 1.3e-09 38.0 0.1 4.6 7.4 0.0 6.4 6 0 0 6 6 6 3 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 KFR02357.1 - 1.5e-08 34.7 0.2 0.85 9.9 0.0 5.6 6 1 0 6 6 6 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFR02357.1 - 1.3e-05 25.2 1.0 0.39 10.8 0.0 4.5 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.11 KFR02357.1 - 0.00015 21.8 1.0 13 5.8 0.0 4.7 4 0 0 4 4 4 0 CD47 immunoglobulin-like domain Tissue_fac PF01108.17 KFR02357.1 - 0.00048 20.0 1.3 0.38 10.6 0.2 3.1 3 0 0 3 3 3 2 Tissue factor fn3_2 PF16893.5 KFR02357.1 - 0.00071 19.7 0.2 1.1 9.4 0.0 3.1 3 0 0 3 3 3 2 Fibronectin type III domain fn3_4 PF16794.5 KFR02357.1 - 0.0025 17.7 0.1 3.2 7.7 0.0 3.2 3 0 0 3 3 3 1 Fibronectin-III type domain Adeno_E3_CR1 PF02440.15 KFR02357.1 - 0.009 15.8 1.7 19 5.1 0.0 4.4 5 0 0 5 5 4 0 Adenovirus E3 region protein CR1 Herpes_gE PF02480.16 KFR02357.1 - 0.022 13.5 0.0 9 4.9 0.0 4.2 5 0 0 5 5 5 0 Alphaherpesvirus glycoprotein E Pur_ac_phosph_N PF16656.5 KFR02357.1 - 0.023 15.3 8.3 0.22 12.1 0.0 4.0 3 1 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain UL141 PF16758.5 KFR02357.1 - 0.025 14.3 0.6 26 4.4 0.0 4.6 5 0 0 5 5 5 0 Herpes-like virus membrane glycoprotein UL141 IL6Ra-bind PF09240.10 KFR02358.1 - 2e-23 82.7 0.4 6.8e-23 80.9 0.1 2.0 2 0 0 2 2 2 1 Interleukin-6 receptor alpha chain, binding Tissue_fac PF01108.17 KFR02358.1 - 1.1e-05 25.2 6.9 0.094 12.6 0.2 3.3 3 0 0 3 3 3 2 Tissue factor Il13Ra_Ig PF18001.1 KFR02358.1 - 0.00028 20.9 0.0 0.0043 17.1 0.0 2.4 2 0 0 2 2 2 1 Interleukin-13 receptor subunit alpha Ig-like domain EpoR_lig-bind PF09067.10 KFR02358.1 - 0.014 15.6 0.6 0.033 14.4 0.3 1.8 2 0 0 2 2 2 0 Erythropoietin receptor, ligand binding PolyA_pol PF01743.20 KFR02359.1 - 3.3e-33 114.8 0.3 5.5e-33 114.1 0.3 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KFR02359.1 - 7.1e-14 51.3 0.1 1.1e-12 47.6 0.0 2.4 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A PRC PF05239.16 KFR02359.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 PRC-barrel domain LON_substr_bdg PF02190.16 KFR02360.1 - 8.4e-25 87.9 0.0 1.1e-24 87.5 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Yippee-Mis18 PF03226.14 KFR02360.1 - 2.2e-11 43.9 0.2 4.5e-11 42.9 0.2 1.5 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Baculo_ME53 PF06061.11 KFR02360.1 - 0.14 11.3 2.3 0.24 10.6 2.3 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 LRR_8 PF13855.6 KFR02361.1 - 1.4e-51 172.1 68.0 1.8e-13 50.0 3.2 6.1 1 1 6 7 7 7 7 Leucine rich repeat LRR_5 PF13306.6 KFR02361.1 - 1e-24 86.9 0.7 1.3e-11 44.5 2.5 4.0 2 1 2 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFR02361.1 - 1.1e-24 86.0 47.6 2.1e-06 27.9 1.4 8.7 4 1 2 9 9 9 6 Leucine Rich repeats (2 copies) I-set PF07679.16 KFR02361.1 - 6e-16 58.3 0.1 3.8e-15 55.7 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin I-set domain LRR_9 PF14580.6 KFR02361.1 - 5.4e-13 48.8 25.0 0.00032 20.2 3.4 4.4 1 1 3 4 4 4 4 Leucine-rich repeat Ig_3 PF13927.6 KFR02361.1 - 7.5e-13 48.9 0.1 2.6e-12 47.2 0.0 2.0 2 0 0 2 2 1 1 Immunoglobulin domain ig PF00047.25 KFR02361.1 - 7.5e-08 32.4 0.1 8.2e-07 29.1 0.0 2.5 3 0 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 KFR02361.1 - 7.1e-07 29.5 0.0 5.5e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain LRRCT PF01463.24 KFR02361.1 - 6.3e-05 23.2 0.1 0.00016 21.9 0.1 1.8 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain V-set PF07686.17 KFR02361.1 - 7e-05 23.0 0.2 0.0016 18.6 0.0 3.0 2 1 0 2 2 2 1 Immunoglobulin V-set domain LRR_1 PF00560.33 KFR02361.1 - 0.00014 21.9 27.4 0.078 13.6 0.2 9.4 10 0 0 10 10 9 1 Leucine Rich Repeat LRRNT PF01462.18 KFR02361.1 - 0.00024 20.6 1.0 0.00024 20.6 1.0 2.2 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain fn3 PF00041.21 KFR02361.1 - 0.0016 18.8 1.5 0.0035 17.7 1.5 1.6 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFR02361.1 - 0.0029 18.1 1.9 0.011 16.3 1.9 2.0 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Ig_6 PF18452.1 KFR02361.1 - 0.012 15.1 0.0 0.097 12.3 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain LRR_6 PF13516.6 KFR02361.1 - 0.026 14.6 16.0 15 6.0 0.1 6.8 4 1 1 5 5 5 0 Leucine Rich repeat Ig_5 PF16681.5 KFR02361.1 - 0.063 13.7 0.0 0.24 11.9 0.0 2.0 1 0 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain SET PF00856.28 KFR02362.1 - 3.4e-21 76.3 0.1 7.1e-20 72.1 0.1 2.2 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 KFR02362.1 - 1.1e-05 26.0 13.5 1.1e-05 26.0 13.5 2.0 2 0 0 2 2 2 1 Pre-SET motif AWS PF17907.1 KFR02362.1 - 0.0016 18.5 4.3 0.0016 18.5 4.3 2.6 3 0 0 3 3 3 1 AWS domain FGE-sulfatase PF03781.16 KFR02363.1 - 1e-87 294.0 7.7 1.1e-87 293.9 7.7 1.0 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Hairy_orange PF07527.13 KFR02364.1 - 4.8e-11 42.7 0.3 1.1e-10 41.6 0.3 1.6 1 0 0 1 1 1 1 Hairy Orange PAS_6 PF08348.11 KFR02364.1 - 0.14 12.1 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 YheO-like PAS domain Arf PF00025.21 KFR02365.1 - 1.1e-39 135.7 0.1 1.3e-39 135.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFR02365.1 - 5.6e-15 55.3 0.0 6.2e-15 55.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR02365.1 - 4.8e-11 42.9 0.0 7.3e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KFR02365.1 - 1e-06 28.3 0.0 1.2e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KFR02365.1 - 1.5e-05 24.4 0.1 2e-05 24.0 0.1 1.4 1 1 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.10 KFR02365.1 - 0.005 16.3 0.0 0.0056 16.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFR02365.1 - 0.012 15.6 0.0 0.026 14.6 0.0 1.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Glyco_hydro_47 PF01532.20 KFR02366.1 - 1.9e-105 353.4 0.0 3.5e-105 352.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 DUF2063 PF09836.9 KFR02366.1 - 0.11 12.7 0.0 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 Putative DNA-binding domain ANF_receptor PF01094.28 KFR02367.1 - 3.4e-21 75.7 0.0 3.9e-21 75.5 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Haem_degrading PF03928.14 KFR02367.1 - 0.02 15.0 0.0 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 Haem-degrading ANF_receptor PF01094.28 KFR02368.1 - 1e-74 251.8 0.0 1.5e-74 251.3 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 KFR02368.1 - 2.3e-61 207.6 14.9 3.1e-61 207.1 14.9 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 KFR02368.1 - 2.7e-13 49.7 11.1 5.2e-13 48.8 11.1 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.6 KFR02368.1 - 0.00056 19.7 0.0 0.0045 16.7 0.0 1.9 2 0 0 2 2 2 1 Periplasmic binding protein PET PF06297.14 KFR02369.1 - 1e-37 128.3 0.1 1.7e-37 127.6 0.1 1.4 1 0 0 1 1 1 1 PET Domain LIM PF00412.22 KFR02369.1 - 1.1e-15 57.6 19.2 1e-10 41.7 3.3 3.4 3 2 0 3 3 3 2 LIM domain Serglycin PF04360.12 KFR02369.1 - 0.094 12.7 0.3 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 Serglycin Caveolin PF01146.17 KFR02370.1 - 5.6e-60 201.1 1.8 6.4e-60 200.9 1.8 1.0 1 0 0 1 1 1 1 Caveolin CCDC117 PF15810.5 KFR02370.1 - 0.15 12.4 0.8 0.22 11.8 0.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 117 7tm_1 PF00001.21 KFR02371.1 - 4e-39 134.5 14.1 4.6e-39 134.3 14.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR02371.1 - 0.002 17.5 13.0 0.003 17.0 13.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Comm PF15957.5 KFR02371.1 - 8 6.8 9.3 5.3 7.4 0.6 2.4 1 1 1 2 2 2 0 Commissureless SAP PF02037.27 KFR02372.1 - 1.2e-11 44.1 0.3 2.6e-11 43.0 0.3 1.6 1 0 0 1 1 1 1 SAP domain zf-C3HC4_2 PF13923.6 KFR02372.1 - 6.2e-09 35.6 8.8 6.2e-09 35.6 8.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFR02372.1 - 4.5e-07 29.6 10.2 4.5e-07 29.6 10.2 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KFR02372.1 - 7.9e-06 25.7 9.3 1.8e-05 24.5 5.9 2.3 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 KFR02372.1 - 5.8e-05 22.9 9.3 5.8e-05 22.9 9.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFR02372.1 - 0.00013 22.2 17.3 0.00017 21.9 12.4 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KFR02372.1 - 0.0018 18.3 10.4 0.0018 18.3 10.4 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFR02372.1 - 0.0025 17.7 13.3 0.0025 17.7 13.3 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-WRNIP1_ubi PF18279.1 KFR02372.1 - 0.01 16.4 4.4 0.019 15.5 0.0 2.8 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-rbx1 PF12678.7 KFR02372.1 - 0.021 15.1 8.1 0.021 15.1 8.1 2.9 2 1 0 2 2 2 0 RING-H2 zinc finger domain LEM PF03020.15 KFR02372.1 - 0.029 13.9 0.2 0.058 13.0 0.2 1.5 1 0 0 1 1 1 0 LEM domain AKAP95 PF04988.12 KFR02372.1 - 0.055 13.7 15.8 0.07 13.4 1.6 3.0 1 1 2 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) GAT PF03127.14 KFR02372.1 - 0.13 12.6 4.1 0.77 10.1 0.0 3.2 3 1 1 4 4 4 0 GAT domain SPT16 PF08644.11 KFR02372.1 - 0.23 11.6 5.4 0.62 10.2 5.4 1.7 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) CTK3_C PF12350.8 KFR02372.1 - 0.52 10.5 4.9 0.98 9.6 1.2 3.0 2 1 0 2 2 2 0 CTD kinase subunit gamma CTK3 C-terminus zf-RING_10 PF16685.5 KFR02372.1 - 5.2 7.3 14.8 0.048 13.8 5.8 2.4 3 0 0 3 3 3 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 KFR02372.1 - 5.5 7.2 20.6 0.65 10.2 14.8 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RhoGAP PF00620.27 KFR02373.1 - 3.4e-48 163.3 0.0 1.2e-47 161.6 0.0 2.0 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 KFR02373.1 - 1.3e-18 67.0 5.0 1.3e-18 67.0 5.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KFR02373.1 - 6e-10 38.6 0.0 2.3e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFR02373.1 - 6e-10 38.6 0.0 1.5e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFR02373.1 - 2.4e-09 36.9 0.0 4.3e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Flg_hook PF02120.16 KFR02373.1 - 0.09 12.7 0.3 0.22 11.4 0.3 1.6 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK FlaC_arch PF05377.11 KFR02373.1 - 0.31 11.5 5.2 0.22 11.9 0.6 3.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DASH_Dad3 PF08656.10 KFR02373.1 - 2.1 8.5 5.6 5.2 7.2 1.1 2.9 2 0 0 2 2 2 0 DASH complex subunit Dad3 TolA_bind_tri PF16331.5 KFR02373.1 - 5.3 7.2 10.9 2.2 8.4 2.6 3.3 2 0 0 2 2 2 0 TolA binding protein trimerisation UPF0020 PF01170.18 KFR02374.1 - 4.1e-48 163.7 0.0 6.1e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 THUMP PF02926.17 KFR02374.1 - 2.5e-13 50.4 0.2 6.1e-12 45.8 0.0 2.3 2 0 0 2 2 2 1 THUMP domain Methyltransf_25 PF13649.6 KFR02374.1 - 0.00035 21.2 0.0 0.0011 19.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 KFR02374.1 - 0.001 18.6 0.0 0.0032 17.0 0.0 1.9 1 1 1 2 2 2 1 RRNA methyltransferase AviRa MTS PF05175.14 KFR02374.1 - 0.016 14.8 0.0 0.054 13.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Fer4_NifH PF00142.18 KFR02374.1 - 0.089 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Methyltransf_11 PF08241.12 KFR02374.1 - 0.13 12.9 0.0 0.36 11.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain BSP_II PF05432.11 KFR02374.1 - 0.2 11.3 15.2 0.27 10.9 15.2 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) NPR3 PF03666.13 KFR02374.1 - 9.2 4.9 7.1 15 4.2 7.1 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 VHL_C PF17211.3 KFR02375.1 - 1.5e-30 105.0 3.2 2.1e-30 104.5 3.2 1.2 1 0 0 1 1 1 1 VHL box domain VHL PF01847.16 KFR02375.1 - 1.3e-10 41.1 0.0 3.1e-10 39.8 0.0 1.6 2 1 0 2 2 2 1 VHL beta domain STAT2_C PF12188.8 KFR02375.1 - 0.057 13.3 0.2 0.1 12.5 0.2 1.5 1 0 0 1 1 1 0 Signal transducer and activator of transcription 2 C terminal Motilin_assoc PF04643.12 KFR02376.1 - 1.2e-25 89.1 0.1 2.4e-25 88.2 0.1 1.5 2 0 0 2 2 2 1 Motilin/ghrelin-associated peptide Motilin_ghrelin PF04644.12 KFR02376.1 - 2.5e-05 24.0 1.3 3.6e-05 23.4 1.3 1.3 1 0 0 1 1 1 1 Motilin/ghrelin DUF3742 PF12553.8 KFR02376.1 - 0.03 14.5 0.0 0.038 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) WTX PF09422.10 KFR02376.1 - 0.065 12.3 0.1 0.07 12.2 0.1 1.1 1 0 0 1 1 1 0 WTX protein WD40 PF00400.32 KFR02377.1 - 4.2e-23 81.2 21.2 0.00053 20.7 0.2 6.6 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR02377.1 - 1.4e-07 31.7 4.9 0.014 15.7 0.1 4.7 2 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFR02377.1 - 0.018 14.1 1.4 0.91 8.4 0.0 2.8 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ribosomal_L32e PF01655.18 KFR02378.1 - 4.5e-58 194.3 3.6 5.2e-58 194.1 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Vps4_C PF09336.10 KFR02379.1 - 0.0051 16.8 0.1 0.016 15.2 0.1 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain CCDC106 PF15794.5 KFR02379.1 - 6.4 6.4 9.6 0.4 10.4 0.2 2.6 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 106 HhH-GPD PF00730.25 KFR02380.1 - 5.3e-05 23.6 0.0 6.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein WD40 PF00400.32 KFR02381.1 - 1.2e-16 60.7 11.1 2.9e-06 27.9 0.0 7.2 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR02381.1 - 8.9e-12 45.2 1.1 0.012 15.9 0.1 5.3 5 1 1 6 6 5 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KFR02381.1 - 3.6e-05 23.0 9.1 0.0049 16.0 0.3 4.9 5 1 0 5 5 5 2 Coatomer WD associated region eIF2A PF08662.11 KFR02381.1 - 0.0014 18.6 0.8 0.32 10.8 0.0 3.5 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A TPR_7 PF13176.6 KFR02381.1 - 0.0057 16.6 6.5 0.077 13.1 0.1 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFR02381.1 - 0.0076 16.5 2.3 1.2 9.5 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFR02381.1 - 0.0079 16.4 9.2 0.17 12.1 0.3 3.8 5 0 0 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 Prok-RING_4 PF14447.6 KFR02381.1 - 0.015 15.2 2.3 0.061 13.2 2.3 2.1 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Ge1_WD40 PF16529.5 KFR02381.1 - 0.019 14.0 0.9 0.25 10.2 0.0 2.7 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Clathrin PF00637.20 KFR02381.1 - 0.035 14.0 4.4 0.88 9.4 0.2 3.8 1 1 2 4 4 4 0 Region in Clathrin and VPS TPR_2 PF07719.17 KFR02381.1 - 0.14 12.4 19.6 0.18 12.0 0.8 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFR02381.1 - 4.9 8.2 7.6 42 5.3 0.1 4.4 5 0 0 5 5 3 0 Tetratricopeptide repeat zf-RING_4 PF14570.6 KFR02381.1 - 9.2 6.1 10.1 13 5.6 2.6 2.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain 7tm_1 PF00001.21 KFR02382.1 - 3.2e-45 154.5 14.7 4.1e-45 154.2 14.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Rhodopsin_N PF10413.9 KFR02382.1 - 2.3e-26 91.3 1.7 2.3e-26 91.3 1.7 2.1 2 0 0 2 2 2 1 Amino terminal of the G-protein receptor rhodopsin 7TM_GPCR_Srw PF10324.9 KFR02382.1 - 1.1e-09 38.1 19.4 3.6e-09 36.4 19.4 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 KFR02382.1 - 1.2e-09 37.9 20.8 1.7e-09 37.5 20.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.9 KFR02382.1 - 5.5e-09 35.8 18.4 7.4e-09 35.4 18.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFR02382.1 - 0.00097 18.9 17.7 0.0076 16.0 17.7 1.9 1 1 0 1 1 1 1 Olfactory receptor TAS2R PF05296.13 KFR02382.1 - 0.0039 16.3 11.4 0.004 16.3 2.2 2.1 2 0 0 2 2 2 2 Taste receptor protein (TAS2R) DUF4407 PF14362.6 KFR02382.1 - 1.5 8.1 3.0 2.8 7.2 2.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Tmemb_cc2 PF10267.9 KFR02384.1 - 2.2e-170 567.1 13.7 2.2e-170 567.1 13.7 1.8 2 0 0 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein LMBR1 PF04791.16 KFR02384.1 - 0.0012 17.9 0.5 0.0012 17.9 0.5 2.2 2 1 0 2 2 2 1 LMBR1-like membrane protein CbiA PF01656.23 KFR02384.1 - 0.018 15.1 0.2 0.098 12.7 0.0 2.1 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain UPF0565 PF10561.9 KFR02384.1 - 0.066 12.4 4.9 0.053 12.7 0.4 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 Exonuc_VII_L PF02601.15 KFR02384.1 - 3.4 7.2 26.1 0.86 9.1 9.1 3.1 3 0 0 3 3 3 0 Exonuclease VII, large subunit GCP_C_terminal PF04130.13 KFR02484.1 - 4.4e-62 210.3 10.6 7.3e-62 209.6 10.6 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KFR02484.1 - 6.2e-47 160.7 0.2 6.2e-47 160.7 0.2 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal Lactamase_B_6 PF16661.5 KFR02485.1 - 0.014 14.8 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain His_Phos_2 PF00328.22 KFR02487.1 - 3.5e-130 434.8 0.1 4.7e-130 434.4 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KFR02487.1 - 6.6e-41 138.4 0.3 1.4e-40 137.3 0.3 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KFR02487.1 - 0.028 14.0 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ATP-gua_Ptrans PF00217.19 KFR02488.1 - 3.1e-73 245.8 0.0 3.9e-73 245.4 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 KFR02488.1 - 7.5e-29 99.9 0.0 1.2e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Thioredoxin PF00085.20 KFR02489.1 - 4.3e-51 171.2 0.0 2.2e-31 107.9 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KFR02489.1 - 2.1e-38 132.1 0.2 2.5e-33 115.5 0.3 2.8 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KFR02489.1 - 1.4e-06 28.7 0.1 0.0028 18.1 0.1 3.2 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFR02489.1 - 2.5e-05 24.5 0.0 0.0034 17.7 0.0 3.3 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_4 PF13462.6 KFR02489.1 - 0.00029 21.0 0.1 0.048 13.8 0.0 3.1 3 0 0 3 3 3 1 Thioredoxin Calsequestrin PF01216.17 KFR02489.1 - 0.0006 19.0 0.0 0.0012 18.0 0.0 1.5 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_7 PF13899.6 KFR02489.1 - 0.008 16.3 0.0 0.022 14.9 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KFR02489.1 - 0.027 13.9 0.0 0.24 10.7 0.0 2.1 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KFR02489.1 - 0.046 13.7 0.1 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 AhpC/TSA family Ras PF00071.22 KFR02490.1 - 9.6e-28 96.8 0.0 1e-27 96.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR02490.1 - 5.6e-22 78.2 0.0 6e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR02490.1 - 8e-08 31.9 0.0 8.2e-08 31.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFR02490.1 - 1.3e-06 28.4 0.0 1.4e-06 28.4 0.0 1.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFR02490.1 - 0.016 14.5 0.0 0.017 14.5 0.0 1.0 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_25 PF13481.6 KFR02490.1 - 0.018 14.6 0.0 0.019 14.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain Serinc PF03348.15 KFR02491.1 - 1.1e-142 476.0 16.0 1.2e-142 475.9 16.0 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) TMEM89 PF15098.6 KFR02491.1 - 0.0078 16.4 0.8 0.014 15.6 0.8 1.4 1 0 0 1 1 1 1 TMEM89 protein family MFAP1 PF06991.11 KFR02492.1 - 1.5e-78 263.6 30.3 1.5e-78 263.6 30.3 2.1 2 0 0 2 2 2 2 Microfibril-associated/Pre-mRNA processing Glyco_hydro_38N PF01074.22 KFR02493.1 - 2e-107 358.8 0.6 2.8e-107 358.4 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KFR02493.1 - 1.8e-42 145.8 0.0 3.1e-42 145.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KFR02493.1 - 3.2e-23 81.7 0.0 8.4e-23 80.4 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KFR02493.1 - 0.041 14.0 0.0 0.23 11.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain MAP65_ASE1 PF03999.12 KFR02494.1 - 1.3e-148 496.4 24.8 1.5e-148 496.2 24.8 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DinI PF06183.13 KFR02494.1 - 0.2 12.0 8.3 0.3 11.4 0.0 3.9 4 0 0 4 4 4 0 DinI-like family DUF4407 PF14362.6 KFR02494.1 - 0.61 9.4 15.9 0.33 10.3 3.3 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF4407) HD_4 PF13328.6 KFR02495.1 - 2e-10 40.6 0.0 2.4e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 HD domain HD PF01966.22 KFR02495.1 - 0.022 15.0 0.5 0.074 13.3 0.5 1.7 1 1 0 1 1 1 0 HD domain TTL PF03133.15 KFR02496.1 - 1.7e-90 303.1 0.6 3.1e-90 302.3 0.6 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KFR02496.1 - 2.5e-09 36.8 0.0 6.1e-05 22.4 0.0 3.4 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KFR02496.1 - 1e-05 24.9 0.0 0.015 14.6 0.0 2.9 3 0 0 3 3 3 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 KFR02496.1 - 0.0037 17.3 0.0 0.013 15.5 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 KFR02496.1 - 0.012 15.3 0.0 3.1 7.3 0.0 2.4 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 KFR02496.1 - 0.16 11.4 0.0 0.39 10.2 0.0 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus EF-hand_7 PF13499.6 KFR02497.1 - 4.5e-14 52.6 5.2 1.6e-12 47.6 2.2 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFR02497.1 - 1e-11 43.5 8.0 2.9e-05 23.3 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KFR02497.1 - 8.5e-11 40.9 5.7 8.8e-05 22.1 0.8 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 KFR02497.1 - 1.1e-07 31.5 6.5 0.0016 18.2 1.9 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFR02497.1 - 3e-07 29.6 3.0 0.015 14.8 0.1 2.6 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 KFR02497.1 - 9.8e-05 22.6 0.9 0.001 19.3 0.5 2.3 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFR02497.1 - 0.0046 16.9 5.8 0.11 12.4 0.2 2.8 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KFR02497.1 - 0.038 14.2 1.0 0.096 12.9 1.0 1.7 1 1 0 1 1 1 0 Dockerin type I domain S_100 PF01023.19 KFR02497.1 - 0.07 12.8 0.2 9.5 6.0 0.0 3.3 3 0 0 3 3 3 0 S-100/ICaBP type calcium binding domain Gal4_dimer PF03902.13 KFR02497.1 - 0.072 13.3 3.3 0.21 11.8 0.3 2.4 1 1 1 2 2 2 0 Gal4-like dimerisation domain NuiA PF07924.11 KFR02497.1 - 0.08 13.3 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein Sema PF01403.19 KFR02498.1 - 6.2e-141 470.0 0.0 7.7e-141 469.7 0.0 1.1 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 KFR02498.1 - 0.0015 19.0 2.6 0.0015 19.0 2.6 2.5 2 0 0 2 2 2 1 Plexin repeat PSI_integrin PF17205.3 KFR02498.1 - 0.3 10.9 4.1 4.3 7.1 0.8 2.6 2 0 0 2 2 2 0 Integrin plexin domain Iso_dh PF00180.20 KFR02499.1 - 6.4e-76 255.8 0.0 7.6e-76 255.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phe_ZIP PF08916.11 KFR02499.1 - 0.23 12.2 0.9 0.99 10.2 0.4 2.1 2 0 0 2 2 2 0 Phenylalanine zipper Clat_adaptor_s PF01217.20 KFR02500.1 - 2.1e-41 141.2 3.0 2.6e-41 140.9 3.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Peptidase_M1_N PF17900.1 KFR02501.1 - 1.8e-53 181.5 0.2 2.1e-53 181.3 0.2 1.0 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 KFR02502.1 - 6.2e-34 118.0 0.0 1.6e-33 116.6 0.0 1.6 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KFR02502.1 - 3.9e-25 88.7 0.0 5.8e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain 7tm_1 PF00001.21 KFR02503.1 - 1.6e-45 155.5 10.5 1.9e-45 155.3 10.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CitMHS PF03600.16 KFR02503.1 - 0.081 12.1 4.5 0.15 11.2 4.5 1.5 1 1 0 1 1 1 0 Citrate transporter EMP24_GP25L PF01105.24 KFR02504.1 - 1.9e-40 138.7 0.1 2.1e-40 138.6 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ank_2 PF12796.7 KFR02505.1 - 1.9e-25 89.2 5.0 7.1e-14 52.2 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFR02505.1 - 1.4e-15 57.5 0.4 8.2e-06 26.3 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFR02505.1 - 5e-14 52.0 2.3 7.9e-06 26.1 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KFR02505.1 - 2.8e-13 49.8 1.7 6.9e-07 29.4 0.1 3.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFR02505.1 - 2.7e-12 45.7 0.3 0.0022 18.3 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat DUF2000 PF09391.10 KFR02505.1 - 0.059 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2000) FMN_dh PF01070.18 KFR02505.1 - 0.1 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Med13_C PF06333.12 KFR02505.1 - 0.1 11.8 1.0 0.16 11.2 1.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain RasGEF PF00617.19 KFR02506.1 - 1.6e-56 191.3 0.3 4.4e-56 189.9 0.3 1.8 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KFR02506.1 - 1.8e-23 82.8 1.0 6.1e-17 61.8 0.1 3.5 3 0 0 3 3 3 2 RasGEF N-terminal motif RhoGEF PF00621.20 KFR02506.1 - 3e-21 76.5 0.2 3e-21 76.5 0.2 2.4 3 0 0 3 3 3 1 RhoGEF domain PH PF00169.29 KFR02506.1 - 8.6e-18 64.8 0.2 8.9e-17 61.5 0.2 2.5 2 0 0 2 2 2 1 PH domain GOLGA2L5 PF15070.6 KFR02506.1 - 0.0032 16.2 2.4 0.0065 15.2 2.4 1.4 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 PH_11 PF15413.6 KFR02506.1 - 0.0094 16.4 1.8 0.095 13.1 1.8 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain IQ PF00612.27 KFR02506.1 - 0.011 15.5 1.6 0.03 14.1 1.6 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif PH_13 PF16652.5 KFR02506.1 - 0.013 15.3 0.1 0.05 13.4 0.1 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain P4Ha_N PF08336.11 KFR02506.1 - 0.05 13.6 0.2 0.24 11.4 0.2 2.3 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF641 PF04859.12 KFR02506.1 - 0.077 13.3 1.8 0.29 11.5 1.8 2.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) PH_9 PF15410.6 KFR02506.1 - 0.13 12.7 0.5 0.77 10.1 0.5 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain Sec34 PF04136.15 KFR02506.1 - 0.31 10.9 3.9 0.4 10.6 0.2 2.6 2 0 0 2 2 2 0 Sec34-like family ADIP PF11559.8 KFR02506.1 - 0.97 9.5 7.7 4.5 7.4 1.5 2.9 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding PI_PP_I PF18363.1 KFR02506.1 - 3.6 7.8 5.4 6.4 7.0 0.1 3.6 4 0 0 4 4 4 0 Phosphoinositide phosphatase insertion domain HR1 PF02185.16 KFR02506.1 - 6.8 6.9 9.8 5.3 7.2 0.1 3.7 3 0 0 3 3 3 0 Hr1 repeat Peptidase_C1 PF00112.23 KFR02507.1 - 2.7e-79 266.3 1.3 3e-79 266.1 1.3 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KFR02507.1 - 2.2e-05 23.4 0.7 0.021 13.6 0.1 2.3 2 0 0 2 2 2 2 Peptidase C1-like family BLM_N PF16202.5 KFR02508.1 - 3.5e-26 92.2 0.0 1.1e-24 87.3 0.0 2.7 2 0 0 2 2 2 1 N-terminal region of Bloom syndrome protein BDHCT PF08072.11 KFR02508.1 - 2.1e-20 72.5 2.6 4.5e-20 71.5 2.6 1.6 1 0 0 1 1 1 1 BDHCT (NUC031) domain DEAD PF00270.29 KFR02508.1 - 1.2e-19 70.8 0.1 3.3e-19 69.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KFR02508.1 - 9.3e-18 64.7 1.5 9.3e-18 64.7 1.5 2.1 2 0 0 2 2 2 1 RecQ zinc-binding BDHCT_assoc PF16204.5 KFR02508.1 - 1.3e-16 61.0 0.1 2.8e-16 59.9 0.1 1.5 1 0 0 1 1 1 1 BDHCT-box associated domain on Bloom syndrome protein Helicase_C PF00271.31 KFR02508.1 - 5.7e-16 58.8 0.0 3.1e-15 56.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.10 KFR02508.1 - 7e-14 51.6 0.1 1.4e-13 50.6 0.1 1.5 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 KFR02508.1 - 1.5e-12 47.3 0.0 3.4e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 HRDC domain SNF2_N PF00176.23 KFR02508.1 - 0.0014 17.4 0.0 0.023 13.5 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.15 KFR02508.1 - 0.025 14.6 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit WD40 PF00400.32 KFR02509.1 - 0.053 14.4 7.7 6 7.9 0.0 5.3 6 0 0 6 6 6 0 WD domain, G-beta repeat FERM_C PF09380.10 KFR02510.1 - 8.7e-15 54.9 0.3 1.6e-14 54.0 0.3 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FA PF08736.11 KFR02510.1 - 3.6e-14 52.6 0.6 7.6e-14 51.5 0.1 1.9 2 0 0 2 2 2 1 FERM adjacent (FA) FERM_M PF00373.18 KFR02510.1 - 2.6e-12 47.2 0.1 9.8e-08 32.4 0.1 2.3 2 0 0 2 2 2 2 FERM central domain FERM_N PF09379.10 KFR02510.1 - 1.1e-10 41.3 0.0 9.4e-10 38.3 0.1 2.2 2 0 0 2 2 2 1 FERM N-terminal domain YcxB PF14317.6 KFR02510.1 - 0.0029 17.3 0.1 0.0061 16.2 0.1 1.5 1 0 0 1 1 1 1 YcxB-like protein HemX PF04375.14 KFR02511.1 - 5.8e-05 22.5 4.7 5.8e-05 22.5 4.7 2.6 2 1 1 3 3 3 1 HemX, putative uroporphyrinogen-III C-methyltransferase FAM76 PF16046.5 KFR02511.1 - 2.1 7.6 31.5 0.027 13.8 22.6 2.1 2 1 0 2 2 2 0 FAM76 protein Lectin_N PF03954.14 KFR02511.1 - 3 7.6 9.0 0.28 10.9 1.9 2.5 1 1 0 2 2 2 0 Hepatic lectin, N-terminal domain MerR-DNA-bind PF09278.11 KFR02511.1 - 5.2 7.7 11.0 14 6.3 0.2 3.6 2 1 1 3 3 3 0 MerR, DNA binding GvpG PF05120.12 KFR02511.1 - 5.2 7.2 11.1 6.3 6.9 2.8 2.7 2 0 0 2 2 2 0 Gas vesicle protein G NIF PF03031.18 KFR02512.1 - 1.6e-55 187.1 1.0 3.2e-55 186.2 1.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase eIF3_subunit PF08597.10 KFR02513.1 - 7.7e-54 183.2 25.2 8.6e-54 183.0 25.2 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Spatacsin_C PF14649.6 KFR02514.1 - 3.2e-103 345.0 1.3 7e-103 343.9 1.3 1.5 1 0 0 1 1 1 1 Spatacsin C-terminus Rep_3 PF01051.21 KFR02514.1 - 0.053 13.3 0.2 6.5 6.5 0.0 2.7 2 0 0 2 2 2 0 Initiator Replication protein FeS_assembly_P PF01883.19 KFR02515.1 - 4.7e-07 29.9 0.0 8.6e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein ADAM_spacer1 PF05986.14 KFR02516.1 - 2.8e-33 114.3 0.0 5.5e-33 113.4 0.0 1.5 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Pep_M12B_propep PF01562.19 KFR02516.1 - 4.6e-33 114.4 0.0 8.7e-33 113.5 0.0 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide TSP_1 PF00090.19 KFR02516.1 - 5.5e-30 103.3 123.0 2.5e-08 34.0 7.5 10.2 11 0 0 11 11 11 8 Thrombospondin type 1 domain Reprolysin PF01421.19 KFR02516.1 - 2.5e-26 92.9 0.1 1e-25 90.8 0.0 2.0 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 KFR02516.1 - 5.3e-21 74.9 7.5 5.3e-21 74.9 7.5 5.6 3 1 1 4 4 4 2 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 KFR02516.1 - 4.8e-14 53.0 0.1 1e-13 51.9 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFR02516.1 - 3.8e-09 37.1 0.2 8.2e-09 36.0 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFR02516.1 - 1.2e-05 25.3 0.0 2.7e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFR02516.1 - 8.8e-05 22.2 0.1 0.00016 21.4 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFR02516.1 - 0.2 11.5 0.3 0.38 10.6 0.3 1.4 1 0 0 1 1 1 0 Matrixin Ank_2 PF12796.7 KFR02517.1 - 3.5e-34 117.3 7.0 8.4e-14 51.9 1.9 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFR02517.1 - 4.4e-25 87.4 4.7 2e-06 28.0 0.2 4.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFR02517.1 - 9.8e-25 86.6 2.3 1.5e-07 31.8 0.1 5.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFR02517.1 - 3.6e-22 76.1 0.5 0.0013 19.0 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 KFR02517.1 - 2.3e-20 72.0 7.7 0.00056 20.2 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Seryl_tRNA_N PF02403.22 KFR02517.1 - 0.0038 17.4 9.7 0.0038 17.4 9.7 12.9 4 2 8 14 14 14 3 Seryl-tRNA synthetase N-terminal domain Tropomyosin PF00261.20 KFR02517.1 - 0.0055 16.1 11.0 0.0055 16.1 11.0 9.3 2 1 5 8 8 8 3 Tropomyosin Kinesin PF00225.23 KFR02518.1 - 8.3e-102 340.5 1.0 2.9e-101 338.7 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain MKLP1_Arf_bdg PF16540.5 KFR02518.1 - 1e-45 154.2 0.0 2.5e-45 152.9 0.0 1.7 1 0 0 1 1 1 1 Arf6-interacting domain of mitotic kinesin-like protein 1 Microtub_bd PF16796.5 KFR02518.1 - 2.2e-14 53.6 0.1 5e-11 42.8 0.0 3.1 3 0 0 3 3 3 2 Microtubule binding ADIP PF11559.8 KFR02518.1 - 0.0049 17.0 12.0 0.0049 17.0 12.0 2.1 2 1 0 2 2 1 1 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 KFR02518.1 - 0.011 15.7 17.9 0.011 15.7 17.9 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PA28_beta PF02252.18 KFR02518.1 - 0.015 15.0 1.4 0.27 10.9 0.0 3.0 3 0 0 3 3 3 0 Proteasome activator pa28 beta subunit SpecificRecomb PF10136.9 KFR02518.1 - 0.039 12.3 2.9 0.057 11.7 2.9 1.2 1 0 0 1 1 1 0 Site-specific recombinase Sec8_exocyst PF04048.14 KFR02518.1 - 0.14 12.0 6.4 0.063 13.2 2.5 2.4 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain ERM PF00769.19 KFR02518.1 - 0.33 10.7 19.7 0.02 14.7 13.0 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF16 PF01519.16 KFR02518.1 - 2.6 8.6 12.1 0.31 11.5 6.5 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF3847 PF12958.7 KFR02518.1 - 2.7 8.2 13.8 12 6.0 5.6 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) V_ATPase_I PF01496.19 KFR02518.1 - 7.2 4.4 11.7 11 3.8 11.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HlyIII PF03006.20 KFR02519.1 - 3.5e-42 144.6 17.3 3.5e-42 144.6 17.3 1.3 2 0 0 2 2 2 1 Haemolysin-III related C5-epim_C PF06662.13 KFR02520.1 - 1e-74 250.1 0.1 1.7e-74 249.4 0.1 1.3 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus DUF4962 PF16332.5 KFR02520.1 - 0.051 12.1 0.2 0.13 10.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4962) LRR_9 PF14580.6 KFR02521.1 - 1.8e-19 69.9 0.2 2.1e-19 69.7 0.2 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KFR02521.1 - 3.3e-17 62.3 23.2 1.2e-09 38.2 1.5 3.3 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFR02521.1 - 1.7e-08 34.1 8.6 1e-06 28.4 4.2 3.0 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 KFR02521.1 - 6.1e-08 32.1 9.6 0.00066 19.5 0.5 3.9 4 0 0 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.33 KFR02521.1 - 6.4e-05 23.0 7.0 0.75 10.6 0.2 4.3 4 0 0 4 4 4 2 Leucine Rich Repeat SDA1 PF05285.12 KFR02521.1 - 0.057 12.8 18.1 0.061 12.8 18.1 1.1 1 0 0 1 1 1 0 SDA1 LRR_2 PF07723.13 KFR02521.1 - 0.12 13.1 3.5 11 6.9 0.1 3.9 4 0 0 4 4 4 0 Leucine Rich Repeat CobT PF06213.12 KFR02521.1 - 0.94 8.8 17.2 1.2 8.5 17.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mpp10 PF04006.12 KFR02521.1 - 1.1 7.6 21.7 1.2 7.4 21.7 1.1 1 0 0 1 1 1 0 Mpp10 protein PPP4R2 PF09184.11 KFR02521.1 - 2.1 7.9 17.4 3.1 7.3 17.4 1.4 1 0 0 1 1 1 0 PPP4R2 DUF1899 PF08953.11 KFR02522.1 - 1.2e-28 98.7 0.1 2.1e-28 98.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KFR02522.1 - 6.4e-20 70.8 0.0 1e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KFR02522.1 - 4e-14 52.8 1.1 0.0043 17.9 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR02522.1 - 4.2e-08 33.4 0.0 0.0019 18.5 0.0 3.7 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFR02522.1 - 0.16 10.9 0.0 4.3 6.2 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Integrin_alpha2 PF08441.12 KFR02523.1 - 1.4e-44 152.8 0.1 2.1e-44 152.2 0.1 1.2 1 0 0 1 1 1 1 Integrin alpha VWA PF00092.28 KFR02523.1 - 1.1e-39 136.5 0.1 1.8e-39 135.8 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain FG-GAP PF01839.23 KFR02523.1 - 4e-15 55.6 10.6 6.9e-07 29.3 0.3 4.4 4 0 0 4 4 4 2 FG-GAP repeat VWA_2 PF13519.6 KFR02523.1 - 1e-14 55.1 0.0 2.7e-14 53.7 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VCBS PF13517.6 KFR02523.1 - 6.3e-08 33.1 0.5 0.0001 22.8 0.2 3.0 2 0 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 KFR02523.1 - 1.7e-06 28.2 8.5 0.15 12.4 0.0 4.8 5 0 0 5 5 5 3 FG-GAP repeat LYRIC PF15686.5 KFR02523.1 - 0.25 10.8 0.1 0.37 10.3 0.1 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Ank_2 PF12796.7 KFR02524.1 - 1.5e-48 163.3 6.4 5.1e-19 68.7 0.8 5.3 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFR02524.1 - 2.9e-38 129.8 9.1 7.3e-12 45.6 0.1 8.1 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFR02524.1 - 7.6e-37 121.1 13.6 4.6e-05 23.5 0.0 9.7 8 1 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 KFR02524.1 - 1.5e-36 123.2 18.9 9.4e-06 25.9 0.1 9.0 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 KFR02524.1 - 7.5e-34 115.4 14.6 2.9e-06 27.4 0.1 8.6 4 2 4 8 8 8 7 Ankyrin repeats (many copies) CLN6 PF15156.6 KFR02525.1 - 7.5e-145 481.5 18.0 8.4e-145 481.3 18.0 1.0 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 6 Zn_dep_PLPC PF00882.18 KFR02525.1 - 0.046 13.7 0.0 0.093 12.7 0.0 1.5 1 1 0 1 1 1 0 Zinc dependent phospholipase C CcmD PF04995.14 KFR02525.1 - 0.34 11.0 2.6 36 4.6 2.4 2.3 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Saf_2TM PF18303.1 KFR02525.1 - 0.85 9.2 5.1 0.65 9.6 2.6 1.9 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Herpes_LMP1 PF05297.11 KFR02525.1 - 5.3 6.1 8.0 1.5 7.9 5.2 1.5 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) EF-hand_7 PF13499.6 KFR02526.1 - 4.2e-18 65.6 0.0 1.2e-07 32.1 0.0 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KFR02526.1 - 1.4e-11 44.5 0.0 2.2e-05 24.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 KFR02526.1 - 4.8e-09 35.4 0.2 0.00036 20.2 0.0 4.4 3 1 1 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KFR02526.1 - 4e-08 32.3 0.7 0.0017 17.7 0.1 4.5 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.6 KFR02526.1 - 8.1e-08 32.0 0.1 8.3e-05 22.4 0.0 2.8 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_11 PF08976.11 KFR02526.1 - 0.0062 17.4 0.0 0.015 16.2 0.0 1.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 KFR02526.1 - 0.066 13.2 0.0 5.2 7.1 0.0 2.2 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand GPHH PF16905.5 KFR02526.1 - 0.15 11.9 0.0 0.41 10.5 0.0 1.7 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated PINIT PF14324.6 KFR02527.1 - 3.4e-39 134.5 0.2 8.8e-39 133.2 0.2 1.7 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KFR02527.1 - 7e-21 73.7 5.0 1.4e-20 72.8 5.0 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KFR02527.1 - 0.00018 21.3 1.5 0.00048 19.9 1.5 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.25 KFR02527.1 - 0.69 9.8 4.9 2.6 8.0 4.9 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MRNIP PF15749.5 KFR02527.1 - 2.2 9.0 8.4 0.39 11.5 0.3 2.3 1 1 0 2 2 2 0 MRN-interacting protein Pkinase PF00069.25 KFR02528.1 - 4.8e-64 216.3 0.0 5.9e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR02528.1 - 9.9e-39 133.2 0.0 1.3e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFR02528.1 - 3.9e-05 22.6 0.0 4.6e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase PB1 PF00564.24 KFR02528.1 - 7.6e-05 22.6 0.1 0.00018 21.4 0.1 1.6 1 0 0 1 1 1 1 PB1 domain Kinase-like PF14531.6 KFR02528.1 - 0.00063 19.2 0.0 0.0014 18.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFR02528.1 - 0.00067 18.7 0.0 0.039 12.9 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KFR02528.1 - 0.09 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Adaptin_binding PF10199.9 KFR02529.1 - 8.4e-17 61.9 0.7 1.4e-16 61.2 0.7 1.4 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Ras PF00071.22 KFR02529.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Ras family MH2 PF03166.14 KFR02530.1 - 1.3e-79 266.8 0.1 1.7e-79 266.4 0.1 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 KFR02530.1 - 1.5e-28 99.0 1.6 3.2e-28 97.9 1.6 1.6 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.9 KFR02530.1 - 0.0065 16.3 0.0 0.0099 15.7 0.0 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 MH2 PF03166.14 KFR02531.1 - 1.2e-56 191.8 0.0 1.4e-56 191.7 0.0 1.0 1 0 0 1 1 1 1 MH2 domain Glyco_hydro_1 PF00232.18 KFR02532.1 - 2.8e-163 543.6 6.5 3.2e-163 543.4 6.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_10 PF00331.20 KFR02532.1 - 0.037 13.2 1.5 0.5 9.5 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 10 DUF3377 PF11857.8 KFR02532.1 - 0.11 12.5 1.3 0.21 11.5 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Zwilch PF09817.9 KFR02533.1 - 3.9e-170 567.1 1.2 1.1e-169 565.6 1.2 1.6 1 1 0 1 1 1 1 RZZ complex, subunit zwilch DUF5601 PF18151.1 KFR02533.1 - 0.16 12.3 0.7 2.7 8.4 0.0 3.3 5 0 0 5 5 5 0 Domain of unknown function (DUF5601) SNAPc19 PF15497.6 KFR02534.1 - 1.1e-22 80.3 18.0 1.3e-22 80.1 18.0 1.0 1 0 0 1 1 1 1 snRNA-activating protein complex subunit 19, SNAPc subunit 19 DUF4724 PF15852.5 KFR02534.1 - 0.059 13.9 0.2 0.069 13.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4724) zf-C4H2 PF10146.9 KFR02534.1 - 2 8.7 12.2 2.2 8.5 12.2 1.0 1 0 0 1 1 1 0 Zinc finger-containing protein Pkinase PF00069.25 KFR02535.1 - 3.7e-62 210.1 0.0 4.7e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR02535.1 - 1.4e-34 119.5 0.0 6.2e-33 114.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFR02535.1 - 5.9e-06 25.3 0.0 8.6e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFR02535.1 - 0.0054 15.7 0.0 0.0067 15.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KFR02535.1 - 0.015 14.4 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 KFR02535.1 - 0.027 13.8 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Swi3 PF07962.12 KFR02536.1 - 2e-34 117.4 0.4 3.1e-34 116.8 0.4 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 HATPase_c_2 PF13581.6 KFR02536.1 - 0.058 13.4 0.2 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain RNB PF00773.19 KFR02537.1 - 1.8e-87 293.7 0.2 3.1e-87 292.9 0.2 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KFR02537.1 - 3.5e-21 75.0 0.3 1.1e-20 73.4 0.0 2.1 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 KFR02537.1 - 5.9e-08 32.8 0.0 0.00014 21.9 0.0 3.2 2 1 0 2 2 2 2 Cold shock domain Rrp44_S1 PF17215.3 KFR02537.1 - 3.5e-07 30.1 0.0 1.1e-06 28.5 0.0 1.9 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 KFR02537.1 - 5.2e-06 26.3 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain EMI PF07546.13 KFR02538.1 - 1.8e-17 63.8 9.3 1.8e-17 63.8 9.3 1.8 2 0 0 2 2 2 1 EMI domain hEGF PF12661.7 KFR02538.1 - 0.018 15.6 5.8 0.018 15.6 5.8 3.4 4 0 0 4 4 4 0 Human growth factor-like EGF EGF_2 PF07974.13 KFR02538.1 - 0.02 15.3 11.1 0.02 15.3 11.1 2.4 2 0 0 2 2 2 0 EGF-like domain Laminin_EGF PF00053.24 KFR02539.1 - 8.3e-53 176.3 297.9 0.00038 20.5 15.8 16.9 7 5 9 16 16 16 16 Laminin EGF domain hEGF PF12661.7 KFR02539.1 - 1.6e-12 47.6 260.2 0.00057 20.4 5.4 22.1 21 2 1 22 22 20 13 Human growth factor-like EGF EGF_2 PF07974.13 KFR02539.1 - 2.3e-08 34.2 371.7 0.0056 17.0 9.9 26.0 21 7 3 24 24 24 12 EGF-like domain Syndecan PF01034.20 KFR02539.1 - 0.0099 15.8 0.2 0.018 14.9 0.2 1.3 1 0 0 1 1 1 1 Syndecan domain EGF PF00008.27 KFR02539.1 - 0.016 15.5 33.8 0.019 15.3 12.9 22.5 23 1 0 23 23 22 0 EGF-like domain MLANA PF14991.6 KFR02539.1 - 0.097 13.0 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A Stevor PF17410.2 KFR02539.1 - 0.12 11.9 0.2 0.21 11.1 0.2 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame EphA2_TM PF14575.6 KFR02539.1 - 0.13 13.2 0.0 0.27 12.1 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SIT PF15330.6 KFR02539.1 - 0.14 12.7 1.4 0.41 11.1 1.4 1.8 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Insulin_TMD PF17870.1 KFR02539.1 - 0.15 12.2 1.2 0.27 11.3 1.2 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment RIFIN PF02009.16 KFR02539.1 - 0.16 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Rifin DUF5385 PF17359.2 KFR02539.1 - 0.29 10.7 0.3 0.4 10.2 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF2207 PF09972.9 KFR02539.1 - 0.34 9.6 0.0 0.46 9.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3951 PF13131.6 KFR02539.1 - 0.4 10.9 3.2 0.57 10.4 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3951) SKG6 PF08693.10 KFR02539.1 - 0.57 9.6 4.4 1.1 8.8 4.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ras PF00071.22 KFR02540.1 - 1.3e-62 210.2 0.1 1.5e-62 210.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR02540.1 - 1.3e-34 119.0 0.1 2.4e-34 118.1 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR02540.1 - 2.5e-11 43.4 0.1 2.9e-11 43.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFR02540.1 - 3.5e-07 30.3 0.0 5.8e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KFR02540.1 - 3.6e-05 24.1 0.1 0.00041 20.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KFR02540.1 - 5e-05 23.3 0.1 0.023 14.6 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFR02540.1 - 0.00015 21.4 0.1 0.00034 20.2 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFR02540.1 - 0.0073 16.7 0.1 0.013 15.9 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 KFR02540.1 - 0.03 13.7 0.0 0.045 13.1 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KFR02540.1 - 0.03 13.9 0.1 0.11 12.1 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.27 KFR02540.1 - 0.034 14.7 0.1 0.046 14.2 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 KFR02540.1 - 0.044 13.8 0.1 0.11 12.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 KFR02540.1 - 0.075 12.5 0.0 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KFR02540.1 - 0.078 12.4 0.3 0.23 10.8 0.0 2.2 2 1 0 2 2 2 0 Bacterial TniB protein FAD-SLDH PF12318.8 KFR02540.1 - 0.084 12.9 0.2 0.2 11.7 0.1 1.6 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase PduV-EutP PF10662.9 KFR02540.1 - 0.09 12.5 0.0 0.24 11.1 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 KFR02540.1 - 0.16 11.8 0.8 0.3 10.9 0.5 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DENN PF02141.21 KFR02541.1 - 1.1e-61 208.1 5.9 1.1e-61 208.1 5.9 2.0 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 KFR02541.1 - 6.7e-17 62.0 0.1 2.9e-16 60.0 0.1 2.3 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KFR02541.1 - 4.6e-14 52.1 5.3 4.6e-14 52.1 5.3 2.1 2 0 0 2 2 2 1 dDENN domain PPR_2 PF13041.6 KFR02541.1 - 6.6e-07 29.4 0.0 2e-05 24.7 0.0 2.6 1 1 1 2 2 2 2 PPR repeat family PPR_3 PF13812.6 KFR02541.1 - 0.00014 21.9 0.3 0.00066 19.7 0.0 2.2 2 1 1 3 3 3 2 Pentatricopeptide repeat domain PPR_long PF17177.4 KFR02541.1 - 0.00014 21.3 0.1 0.0011 18.4 0.0 2.4 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KFR02541.1 - 0.0086 16.3 0.0 0.054 13.8 0.0 2.4 2 0 0 2 2 2 1 PPR repeat Papo_T_antigen PF02380.15 KFR02541.1 - 0.24 11.6 4.9 0.16 12.1 1.0 2.5 2 0 0 2 2 2 0 T-antigen specific domain Na_Ca_ex PF01699.24 KFR02543.1 - 2.8e-58 196.2 48.7 2e-31 109.0 24.0 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein PPP4R2 PF09184.11 KFR02543.1 - 3.2 7.3 11.5 4.8 6.7 11.5 1.3 1 0 0 1 1 1 0 PPP4R2 PBP1_TM PF14812.6 KFR02543.1 - 7.9 6.9 7.7 0.64 10.4 1.9 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PTPLA PF04387.14 KFR02544.1 - 1.1e-49 168.3 3.0 1.7e-49 167.8 3.0 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DPPIV_N PF00930.21 KFR02545.1 - 1.7e-99 332.9 0.0 2.3e-99 332.5 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KFR02545.1 - 1.5e-60 204.3 0.0 2.8e-60 203.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KFR02545.1 - 5e-08 32.9 0.0 9.1e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KFR02545.1 - 0.0007 20.3 0.0 0.0015 19.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFR02545.1 - 0.03 14.0 1.1 0.083 12.5 1.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KFR02545.1 - 0.05 13.4 0.0 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.20 KFR02545.1 - 0.081 12.5 0.1 0.3 10.7 0.1 1.9 1 1 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 KFR02545.1 - 0.18 11.6 0.0 0.43 10.4 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold fn3 PF00041.21 KFR02546.1 - 1.6e-63 211.0 14.0 1e-15 57.9 1.3 5.5 5 0 0 5 5 5 5 Fibronectin type III domain I-set PF07679.16 KFR02546.1 - 3.7e-51 171.1 0.3 2.3e-18 66.1 0.0 5.9 5 1 0 5 5 5 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR02546.1 - 7.7e-51 170.6 2.7 9.2e-16 58.2 0.1 6.2 5 1 1 6 6 6 4 Immunoglobulin domain Ig_2 PF13895.6 KFR02546.1 - 4e-34 116.8 0.3 5.3e-10 39.5 0.0 5.0 4 1 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 KFR02546.1 - 1.6e-28 98.7 0.2 6.2e-09 35.9 0.0 6.2 4 1 1 5 5 5 4 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFR02546.1 - 8.3e-20 71.2 9.9 0.00078 20.0 0.0 6.1 6 0 0 6 6 5 4 Purple acid Phosphatase, N-terminal domain V-set PF07686.17 KFR02546.1 - 2.4e-17 63.1 1.7 0.0084 16.3 0.0 7.9 6 3 1 7 7 7 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFR02546.1 - 3.8e-10 39.7 0.2 0.075 13.1 0.0 4.5 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFR02546.1 - 8.5e-08 31.7 0.0 0.15 11.7 0.0 4.2 4 0 0 4 4 4 3 Immunoglobulin domain Ig_5 PF16681.5 KFR02546.1 - 3.9e-06 27.2 0.0 0.32 11.4 0.0 4.8 4 1 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFR02546.1 - 0.00082 19.6 0.0 4.2 7.7 0.0 4.2 4 0 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 KFR02546.1 - 0.0094 16.0 0.3 0.52 10.4 0.0 3.3 3 0 0 3 3 3 1 C17orf99 Ig domain Interfer-bind PF09294.10 KFR02546.1 - 0.012 16.0 2.2 1.5 9.1 0.2 3.7 4 0 0 4 4 3 0 Interferon-alpha/beta receptor, fibronectin type III Izumo-Ig PF16706.5 KFR02546.1 - 0.012 15.7 0.0 1.8 8.7 0.0 3.5 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain SusE PF14292.6 KFR02546.1 - 0.036 14.3 0.7 0.59 10.4 0.1 2.9 3 0 0 3 3 3 0 SusE outer membrane protein Cadherin PF00028.17 KFR02546.1 - 0.19 12.2 0.3 3.2 8.2 0.1 2.5 2 0 0 2 2 2 0 Cadherin domain Adeno_E3_CR2 PF02439.15 KFR02546.1 - 0.33 10.7 5.4 0.88 9.4 5.4 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 I-set PF07679.16 KFR02547.1 - 1.3e-59 198.2 0.0 1.4e-21 76.3 0.0 4.8 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR02547.1 - 3.5e-53 178.1 0.0 3.2e-15 56.5 0.1 4.6 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFR02547.1 - 2.2e-34 117.6 0.0 8.7e-08 32.4 0.0 4.5 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 KFR02547.1 - 4.6e-31 106.8 0.0 9.4e-09 35.3 0.0 4.8 4 1 0 4 4 4 4 Immunoglobulin domain fn3 PF00041.21 KFR02547.1 - 4e-23 81.5 2.0 2.1e-13 50.4 0.4 2.7 2 0 0 2 2 2 2 Fibronectin type III domain V-set PF07686.17 KFR02547.1 - 6e-19 68.2 2.9 5.7e-05 23.3 0.0 6.8 4 3 1 5 5 5 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFR02547.1 - 1.8e-13 50.4 0.3 1.7e-06 28.0 0.1 4.8 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFR02547.1 - 5.4e-07 29.9 0.4 0.015 15.6 0.0 3.6 5 0 0 5 5 4 2 Immunoglobulin C1-set domain Pur_ac_phosph_N PF16656.5 KFR02547.1 - 0.00042 20.8 1.4 0.0013 19.3 1.4 1.9 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Ig_C17orf99 PF17736.1 KFR02547.1 - 0.00071 19.6 0.3 0.013 15.5 0.0 3.3 4 0 0 4 4 4 1 C17orf99 Ig domain Ig_6 PF18452.1 KFR02547.1 - 0.0013 18.2 0.0 1.4 8.6 0.0 3.5 4 0 0 4 4 4 1 Immunoglobulin domain C2-set PF05790.15 KFR02547.1 - 0.0031 17.6 0.0 41 4.5 0.0 4.1 4 0 0 4 4 4 0 Immunoglobulin C2-set domain BiPBP_C PF06832.12 KFR02547.1 - 0.02 14.9 0.0 3.8 7.6 0.0 2.8 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family Interfer-bind PF09294.10 KFR02547.1 - 0.059 13.7 0.3 0.15 12.4 0.3 1.7 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III Adeno_E3_CR2 PF02439.15 KFR02547.1 - 0.089 12.6 4.6 0.21 11.4 4.6 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PARP PF00644.20 KFR02548.1 - 8e-32 110.4 0.0 9.9e-32 110.1 0.0 1.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ARTD15_N PF18084.1 KFR02548.1 - 0.00062 20.0 0.2 0.0013 19.0 0.2 1.6 1 0 0 1 1 1 1 ARTD15 N-terminal domain SdpI PF13630.6 KFR02548.1 - 0.02 15.0 0.1 0.045 13.9 0.1 1.5 1 0 0 1 1 1 0 SdpI/YhfL protein family 7tm_1 PF00001.21 KFR02549.1 - 1.9e-48 165.1 12.8 2.4e-48 164.7 12.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR02549.1 - 6.1e-07 29.1 8.7 8.9e-07 28.5 8.7 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Git3 PF11710.8 KFR02549.1 - 0.017 14.9 9.5 0.018 14.8 8.7 1.6 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 ArsP_2 PF11449.8 KFR02549.1 - 0.53 9.4 6.9 0.064 12.5 0.6 2.0 2 0 0 2 2 2 0 Putative, 10TM heavy-metal exporter Ig_3 PF13927.6 KFR02550.1 - 7.2e-13 48.9 0.0 2.9e-12 47.0 0.0 2.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFR02550.1 - 5.1e-11 42.8 0.0 1.3e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain CarbopepD_reg_2 PF13715.6 KFR02550.1 - 2.3e-09 37.2 0.0 0.00044 20.2 0.0 2.9 2 0 0 2 2 2 2 CarboxypepD_reg-like domain CarboxypepD_reg PF13620.6 KFR02550.1 - 1.3e-08 34.9 0.1 4e-07 30.2 0.0 2.9 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain I-set PF07679.16 KFR02550.1 - 3.7e-08 33.3 0.0 1e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain TSP_1 PF00090.19 KFR02550.1 - 1.4e-07 31.6 10.7 1.4e-07 31.6 10.7 3.3 3 0 0 3 3 3 1 Thrombospondin type 1 domain ig PF00047.25 KFR02550.1 - 4.8e-07 29.9 0.0 2.8e-06 27.4 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFR02550.1 - 0.043 14.0 0.0 1.5 9.0 0.0 3.0 1 1 1 2 2 2 0 Immunoglobulin V-set domain bMG3 PF11974.8 KFR02550.1 - 0.11 12.5 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain Formyl_trans_N PF00551.19 KFR02551.1 - 2.1e-24 86.3 0.0 3.3e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 KFR02551.1 - 3e-11 43.4 0.1 9.8e-11 41.8 0.0 1.9 2 0 0 2 2 2 1 Formyl transferase, C-terminal domain Rhamno_transf PF11316.8 KFR02551.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative rhamnosyl transferase OSTbeta PF15048.6 KFR02552.1 - 4.7e-30 104.2 0.2 5.8e-30 103.9 0.2 1.1 1 0 0 1 1 1 1 Organic solute transporter subunit beta protein Saf_2TM PF18303.1 KFR02552.1 - 0.024 14.2 0.1 0.034 13.8 0.1 1.2 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Ras PF00071.22 KFR02553.1 - 8.6e-33 113.2 0.0 1.1e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR02553.1 - 1.5e-08 34.9 0.0 2.3e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR02553.1 - 0.0008 18.9 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF815 PF05673.13 KFR02553.1 - 0.14 11.3 0.0 1.6 7.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) UBA PF00627.31 KFR02554.1 - 9e-05 22.3 0.8 0.018 15.0 0.1 2.3 2 0 0 2 2 2 2 UBA/TS-N domain Sigma54_CBD PF04963.13 KFR02554.1 - 0.011 15.7 0.4 0.011 15.6 0.4 1.2 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain WIYLD PF10440.9 KFR02554.1 - 0.018 14.8 0.0 2.2 8.1 0.0 2.7 1 1 2 3 3 3 0 Ubiquitin-binding WIYLD domain UBA_3 PF09288.10 KFR02554.1 - 0.035 13.9 1.1 0.9 9.4 0.7 2.5 2 1 0 2 2 2 0 Fungal ubiquitin-associated domain Raf1_HTH PF18579.1 KFR02554.1 - 0.097 12.4 0.3 2.9 7.7 0.0 2.1 1 1 1 2 2 2 0 Rubisco accumulation factor 1 helix turn helix domain PDCD7 PF16021.5 KFR02556.1 - 2e-101 339.2 24.0 2.2e-101 339.0 24.0 1.0 1 0 0 1 1 1 1 Programmed cell death protein 7 CENP-Q PF13094.6 KFR02556.1 - 0.13 12.5 24.5 0.25 11.6 8.6 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Bac_GDH PF05088.12 KFR02556.1 - 0.81 7.1 8.4 1 6.8 8.4 1.2 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase AAA_2 PF07724.14 KFR02557.1 - 1.9e-41 142.0 0.0 3.2e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 KFR02557.1 - 4.1e-15 55.6 0.0 9.6e-15 54.4 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KFR02557.1 - 1.1e-13 51.7 0.0 2.1e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFR02557.1 - 1.2e-05 25.3 0.0 3.1e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KFR02557.1 - 2.4e-05 24.1 0.0 0.0002 21.1 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_7 PF12775.7 KFR02557.1 - 6.9e-05 22.4 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 KFR02557.1 - 9.2e-05 21.9 0.0 0.011 15.2 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KFR02557.1 - 0.00028 21.2 0.1 0.001 19.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFR02557.1 - 0.0026 18.2 0.0 0.0075 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KFR02557.1 - 0.0058 16.7 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KFR02557.1 - 0.0068 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 KFR02557.1 - 0.0069 16.5 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 KFR02557.1 - 0.0079 15.9 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein T2SSE PF00437.20 KFR02557.1 - 0.0087 15.2 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein TsaE PF02367.17 KFR02557.1 - 0.022 14.7 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KFR02557.1 - 0.026 14.5 0.3 0.074 13.0 0.3 1.9 1 1 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 KFR02557.1 - 0.057 13.1 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFR02557.1 - 0.061 13.8 0.1 0.17 12.4 0.0 1.8 2 0 0 2 2 1 0 ABC transporter AAA_18 PF13238.6 KFR02557.1 - 0.065 13.8 0.0 0.21 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KFR02557.1 - 0.1 11.7 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain PduV-EutP PF10662.9 KFR02557.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 KFR02557.1 - 0.17 11.7 0.0 0.42 10.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 KFR02557.1 - 0.17 11.0 0.1 0.3 10.2 0.1 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_25 PF13481.6 KFR02557.1 - 0.18 11.3 0.0 0.63 9.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain zinc_ribbon_4 PF13717.6 KFR02557.1 - 0.2 11.6 4.9 9.1 6.3 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 KFR02557.1 - 0.47 10.5 4.4 0.91 9.6 4.4 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Ribosomal_S27e PF01667.17 KFR02557.1 - 0.69 9.7 4.3 2.4 8.0 3.9 2.1 2 0 0 2 2 2 0 Ribosomal protein S27 Abhydrolase_1 PF00561.20 KFR02558.1 - 3.9e-08 33.3 0.0 6.7e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFR02558.1 - 3.2e-06 27.9 0.0 4.1e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFR02558.1 - 0.0018 17.6 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KFR02558.1 - 0.0071 15.1 0.0 0.01 14.5 0.0 1.2 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.20 KFR02558.1 - 0.0072 16.5 0.1 0.013 15.6 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.7 KFR02558.1 - 0.033 13.9 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ank_4 PF13637.6 KFR02559.1 - 5.2e-51 170.4 24.0 8.6e-12 45.3 0.2 6.2 3 1 4 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFR02559.1 - 6e-47 158.2 13.6 2.3e-14 53.7 0.1 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFR02559.1 - 1.4e-46 155.9 15.3 2.1e-11 43.8 0.0 8.4 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFR02559.1 - 6.2e-36 118.3 13.1 2.3e-05 24.4 0.0 9.1 9 0 0 9 9 9 8 Ankyrin repeat Ank PF00023.30 KFR02559.1 - 6.3e-34 114.9 16.7 8.5e-10 38.6 0.1 9.0 8 1 1 9 9 9 8 Ankyrin repeat Death PF00531.22 KFR02559.1 - 0.0059 16.7 0.1 0.017 15.2 0.1 1.8 1 0 0 1 1 1 1 Death domain VWA_3_C PF18571.1 KFR02559.1 - 0.062 13.2 0.6 0.88 9.5 0.1 3.1 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain Peptidase_S8 PF00082.22 KFR02561.1 - 2.6e-49 168.1 0.3 3.7e-49 167.6 0.3 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KFR02561.1 - 3.1e-32 110.5 0.1 5e-32 109.8 0.1 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KFR02561.1 - 1.1e-13 51.8 1.4 2.2e-13 50.8 1.4 1.6 1 0 0 1 1 1 1 Peptidase S8 pro-domain GF_recep_IV PF14843.6 KFR02561.1 - 1.1e-13 51.1 90.9 1.6e-09 37.6 32.2 4.0 1 1 3 4 4 4 3 Growth factor receptor domain IV Furin-like_2 PF15913.5 KFR02561.1 - 1.7e-12 47.4 62.6 2.8e-05 24.2 15.1 4.1 2 2 1 3 3 3 3 Furin-like repeat, cysteine-rich PLAC PF08686.11 KFR02561.1 - 1.5e-06 28.8 10.1 1.5e-06 28.8 10.1 3.2 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain VSP PF03302.13 KFR02561.1 - 0.062 12.2 63.5 0.12 11.2 12.0 4.7 1 1 3 4 4 4 0 Giardia variant-specific surface protein LRR_9 PF14580.6 KFR02562.1 - 2.3e-78 261.7 1.4 2.9e-78 261.4 1.4 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KFR02562.1 - 1e-07 32.2 8.1 0.00048 20.4 2.3 2.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFR02562.1 - 2.6e-05 23.9 5.3 0.00013 21.6 4.3 2.3 1 1 1 2 2 2 2 Leucine rich repeat Selenoprotein_S PF06936.11 KFR02563.1 - 1.2e-63 214.4 9.2 1.4e-63 214.3 9.2 1.0 1 0 0 1 1 1 1 Selenoprotein S (SelS) Trp_oprn_chp PF09534.10 KFR02563.1 - 0.38 10.5 2.1 0.61 9.9 2.1 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CHGN PF05679.16 KFR02564.1 - 6.9e-202 671.8 1.6 8e-202 671.6 1.6 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 KFR02564.1 - 8.6e-14 51.6 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Glyco_transf_7C PF02709.14 KFR02564.1 - 1.5e-09 37.3 0.2 3.8e-09 36.1 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KFR02564.1 - 4.8e-06 26.2 0.7 0.00016 21.2 0.1 2.4 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Galactosyl_T PF01762.21 KFR02564.1 - 0.00023 21.0 0.1 0.0049 16.7 0.1 2.9 2 1 0 2 2 2 1 Galactosyltransferase Glyco_transf_21 PF13506.6 KFR02564.1 - 0.014 14.8 0.0 0.23 10.9 0.0 2.6 2 1 0 2 2 2 0 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KFR02564.1 - 0.18 11.6 0.0 14 5.4 0.0 2.9 3 0 0 3 3 3 0 Glycosyl transferase family 2 Pkinase PF00069.25 KFR02565.1 - 8.5e-39 133.5 0.0 3.6e-38 131.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR02565.1 - 1.7e-36 125.8 0.0 2.9e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 KFR02565.1 - 2.6e-26 91.1 21.4 3e-07 30.1 2.2 6.3 6 0 0 6 6 6 5 Leucine rich repeat COR PF16095.5 KFR02565.1 - 1.1e-24 87.3 0.1 2.4e-24 86.3 0.1 1.5 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 KFR02565.1 - 1.1e-22 80.5 0.0 3.9e-22 78.7 0.0 2.0 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase LRR_4 PF12799.7 KFR02565.1 - 2.4e-22 78.6 30.6 1.1e-05 25.7 1.1 8.1 6 2 2 8 8 8 7 Leucine Rich repeats (2 copies) Ank_2 PF12796.7 KFR02565.1 - 1.2e-12 48.2 0.2 2.9e-05 24.6 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFR02565.1 - 5.1e-07 30.1 0.2 0.004 17.7 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFR02565.1 - 2.1e-06 27.6 0.8 0.49 11.1 0.0 5.1 4 0 0 4 4 4 1 Ankyrin repeat Ras PF00071.22 KFR02565.1 - 2.5e-06 27.2 0.0 5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KFR02565.1 - 7.9e-06 25.4 0.0 1.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Ank_5 PF13857.6 KFR02565.1 - 0.00041 20.6 2.8 2.8 8.4 0.0 4.5 2 2 2 4 4 4 1 Ankyrin repeats (many copies) LRR_1 PF00560.33 KFR02565.1 - 0.00071 19.8 21.6 12 6.9 0.0 9.8 8 1 1 9 9 9 0 Leucine Rich Repeat Ank PF00023.30 KFR02565.1 - 0.0021 18.4 1.6 2.4 8.7 0.1 3.8 4 0 0 4 4 3 1 Ankyrin repeat MMR_HSR1 PF01926.23 KFR02565.1 - 0.03 14.4 0.0 0.072 13.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFR02565.1 - 0.062 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TniB PF05621.11 KFR02565.1 - 0.071 12.5 0.2 0.2 11.0 0.1 1.7 2 0 0 2 2 2 0 Bacterial TniB protein malic PF00390.19 KFR02565.1 - 0.21 11.3 0.2 13 5.5 0.0 2.3 2 0 0 2 2 2 0 Malic enzyme, N-terminal domain LRR_6 PF13516.6 KFR02565.1 - 5.7 7.3 25.4 2.6 8.3 0.3 8.1 8 0 0 8 8 8 0 Leucine Rich repeat Aldedh PF00171.22 KFR02566.1 - 2e-184 613.4 0.0 2.3e-184 613.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KFR02566.1 - 0.0071 15.8 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LINES_N PF14694.6 KFR02567.1 - 1.6e-134 448.9 12.1 2.6e-134 448.1 12.1 1.4 1 0 0 1 1 1 1 Lines N-terminus LINES_C PF14695.6 KFR02567.1 - 1.2e-17 63.1 1.2 3e-17 61.8 1.2 1.7 1 0 0 1 1 1 1 Lines C-terminus ADAM_spacer1 PF05986.14 KFR02568.1 - 3.5e-28 97.9 0.0 6.1e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.19 KFR02568.1 - 1.5e-25 89.1 85.3 4.1e-11 42.9 9.2 7.2 6 1 0 6 6 5 4 Thrombospondin type 1 domain ADAM_CR_2 PF17771.1 KFR02568.1 - 1.2e-22 80.2 12.4 9.4e-21 74.1 6.6 7.4 6 2 1 7 7 5 2 ADAM cysteine-rich domain Reprolysin PF01421.19 KFR02568.1 - 7.8e-21 74.9 0.7 9.1e-16 58.3 0.2 2.7 2 0 0 2 2 2 2 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 KFR02568.1 - 2.8e-13 50.5 0.5 9.3e-13 48.8 0.5 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFR02568.1 - 2e-10 41.2 0.0 4.4e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFR02568.1 - 3e-07 30.5 0.7 9.9e-07 28.8 0.7 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFR02568.1 - 3.9e-05 23.4 1.9 7.8e-05 22.4 0.1 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like PLAC PF08686.11 KFR02568.1 - 0.0026 18.5 9.4 0.0026 18.5 9.4 3.1 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain Peptidase_M10 PF00413.24 KFR02568.1 - 0.0051 16.7 0.0 0.0084 16.0 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.9 KFR02568.1 - 0.13 11.2 0.2 0.28 10.1 0.2 1.4 1 0 0 1 1 1 0 Peptidase M66 SRF-TF PF00319.18 KFR02569.1 - 5.6e-24 83.4 0.4 9.6e-24 82.6 0.4 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C PF12347.8 KFR02569.1 - 3.6e-07 30.1 0.0 3.6e-07 30.1 0.0 3.2 4 0 0 4 4 4 1 Holliday junction regulator protein family C-terminal repeat GHD PF17834.1 KFR02569.1 - 0.13 12.4 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Beta-sandwich domain in beta galactosidase TFIIA PF03153.13 KFR02569.1 - 0.26 11.2 10.2 0.4 10.6 10.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LRR_8 PF13855.6 KFR02570.1 - 9.1e-23 79.8 31.1 1.7e-11 43.7 2.0 5.2 3 2 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KFR02570.1 - 5.7e-16 58.4 19.4 2.2e-05 24.7 0.4 5.6 2 1 5 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFR02570.1 - 6.8e-05 22.9 14.9 21 6.2 0.0 8.0 8 1 0 8 8 8 2 Leucine Rich Repeat LRR_9 PF14580.6 KFR02570.1 - 0.00038 20.0 9.1 0.0017 17.9 1.2 3.2 2 1 2 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 KFR02570.1 - 0.091 12.9 11.4 22 5.4 0.1 6.2 6 0 0 6 6 6 0 Leucine Rich repeat Filament PF00038.21 KFR02571.1 - 1.7e-17 64.0 17.0 1.7e-17 64.0 17.0 2.9 3 0 0 3 3 3 1 Intermediate filament protein DUF568 PF04526.13 KFR02571.1 - 0.11 13.2 0.0 0.7 10.7 0.0 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF568) HisKA PF00512.25 KFR02571.1 - 1.2 9.2 3.7 5.3 7.2 3.7 2.1 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain Pkinase_Tyr PF07714.17 KFR02572.1 - 3.2e-95 318.3 0.0 4.7e-95 317.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR02572.1 - 2.4e-40 138.6 0.0 3.8e-40 137.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.20 KFR02572.1 - 8.5e-33 113.3 34.2 8.5e-33 113.3 34.2 2.1 2 0 0 2 2 2 1 Furin-like cysteine rich region Recep_L_domain PF01030.24 KFR02572.1 - 5.9e-30 103.7 0.7 1.1e-29 102.8 0.7 1.5 1 0 0 1 1 1 1 Receptor L domain fn3 PF00041.21 KFR02572.1 - 2.3e-19 69.5 6.3 2.3e-06 27.9 0.1 4.7 4 1 0 4 4 4 4 Fibronectin type III domain Kinase-like PF14531.6 KFR02572.1 - 0.00067 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Insulin_TMD PF17870.1 KFR02572.1 - 0.075 13.1 0.3 0.18 11.9 0.3 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Peptidase_C15 PF01470.17 KFR02574.1 - 3.4e-19 69.8 0.0 4.4e-19 69.5 0.0 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase PgaPase_1 PF06162.12 KFR02574.1 - 5.8e-05 22.9 0.0 7.8e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Putative pyroglutamyl peptidase PgaPase_1 Acetyltransf_7 PF13508.7 KFR02575.1 - 0.033 14.6 0.0 0.072 13.5 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KFR02575.1 - 0.043 13.8 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_1 PF00583.25 KFR02575.1 - 0.057 13.6 0.0 0.099 12.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-U1 PF06220.12 KFR02575.1 - 0.11 12.2 0.6 11 5.8 0.0 2.8 3 0 0 3 3 3 0 U1 zinc finger Acetyltransf_10 PF13673.7 KFR02575.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Arrestin_C PF02752.22 KFR02576.1 - 1e-22 81.0 0.1 3.1e-21 76.2 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KFR02576.1 - 1.2e-19 70.8 0.0 3e-18 66.3 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 KFR02576.1 - 0.04 13.1 0.1 0.069 12.3 0.1 1.3 1 0 0 1 1 1 0 Rgp1 Vps26 PF03643.15 KFR02576.1 - 0.11 11.4 0.0 0.18 10.8 0.0 1.4 1 1 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 AHJR-like PF18743.1 KFR02577.1 - 0.0012 18.4 0.4 0.0017 17.9 0.4 1.2 1 0 0 1 1 1 1 REase_AHJR-like L_protein_N PF15518.6 KFR02577.1 - 0.05 13.4 0.0 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 L protein N-terminus Hormone_recep PF00104.30 KFR02578.1 - 1.6e-39 135.6 0.1 2.4e-39 135.0 0.1 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFR02578.1 - 8.4e-31 106.2 17.1 8.4e-31 106.2 17.1 1.7 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) C2 PF00168.30 KFR02580.1 - 2.6e-32 111.2 0.1 1.9e-21 76.3 0.0 2.1 2 0 0 2 2 2 2 C2 domain cPLA2_C2 PF18695.1 KFR02580.1 - 0.0048 16.9 0.1 0.0088 16.0 0.1 1.4 1 0 0 1 1 1 1 Cytosolic phospholipases A2 C2-domain DUF4497 PF14924.6 KFR02580.1 - 0.024 15.1 0.0 1.7 9.2 0.0 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF4497) 2OG-FeII_Oxy_4 PF13661.6 KFR02580.1 - 0.058 14.1 0.0 0.1 13.3 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily RGM_C PF06534.13 KFR02583.1 - 1.9e-73 245.6 0.1 2.8e-73 245.1 0.1 1.2 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) C-terminus RGM_N PF06535.12 KFR02583.1 - 2.7e-72 242.3 1.6 4.2e-72 241.7 1.6 1.3 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) N-terminus C8 PF08742.11 KFR02583.1 - 1.3 9.5 6.0 2.5 8.6 0.0 3.0 3 0 0 3 3 3 0 C8 domain SNF2_N PF00176.23 KFR02584.1 - 5e-67 226.1 0.3 9.6e-67 225.2 0.3 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain CDH1_2_SANT_HL1 PF18375.1 KFR02584.1 - 4.2e-34 117.1 0.0 4.2e-34 117.1 0.0 5.6 5 0 0 5 5 5 1 CDH1/2 SANT-Helical linker 1 Chromo PF00385.24 KFR02584.1 - 4.6e-32 109.7 11.1 3.2e-21 75.0 0.0 3.8 3 1 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 KFR02584.1 - 4.2e-25 88.0 0.9 4.2e-25 88.0 0.9 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 KFR02584.1 - 7.3e-20 71.4 0.0 2.7e-19 69.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFR02584.1 - 2.7e-08 34.0 0.0 2.7e-08 34.0 0.0 3.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CHDCT2 PF08074.11 KFR02584.1 - 0.00025 21.3 0.2 0.011 16.0 0.1 3.2 2 0 0 2 2 2 1 CHDCT2 (NUC038) domain Myb_DNA-binding PF00249.31 KFR02584.1 - 0.0028 17.8 0.1 0.052 13.8 0.1 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF1180 PF06679.12 KFR02585.1 - 5.7e-19 69.1 1.1 6e-19 69.1 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Glyco_transf_29 PF00777.18 KFR02586.1 - 5.5e-74 249.0 0.0 6.2e-74 248.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) OATP PF03137.20 KFR02587.1 - 1.2e-175 585.0 7.1 1.4e-175 584.8 7.1 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFR02587.1 - 1.8e-26 93.0 8.0 1.8e-26 93.0 8.0 2.9 2 2 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.15 KFR02587.1 - 8e-07 29.1 14.0 1.3e-06 28.4 10.3 2.5 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFR02587.1 - 0.01 15.8 8.8 0.049 13.7 8.8 2.1 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain PUCC PF03209.15 KFR02587.1 - 0.27 10.2 14.0 0.27 10.2 0.1 3.8 4 0 0 4 4 4 0 PUCC protein D_CNTX PF17492.2 KFR02587.1 - 1.8 8.8 0.0 1.8 8.8 0.0 3.4 4 0 0 4 4 4 0 Delta Ctenitoxins MFS_1 PF07690.16 KFR02588.1 - 5.7e-38 130.7 27.6 4.9e-25 88.2 16.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFR02588.1 - 7.8e-34 117.3 19.8 6.7e-30 104.3 6.8 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter Pentapeptide_4 PF13599.6 KFR02588.1 - 3.8e-09 36.6 4.8 6.5e-09 35.8 4.8 1.3 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) MFS_4 PF06779.14 KFR02588.1 - 0.0016 17.8 8.9 0.0016 17.8 8.9 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 KFR02588.1 - 0.0017 17.3 7.2 0.059 12.2 1.3 2.5 2 1 0 2 2 2 2 MFS_1 like family Pentapeptide_3 PF13576.6 KFR02588.1 - 0.0047 17.0 3.6 0.036 14.2 1.8 2.7 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) MFS_3 PF05977.13 KFR02588.1 - 0.034 12.5 6.7 0.27 9.6 1.4 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Pentapeptide PF00805.22 KFR02588.1 - 0.13 11.9 0.0 1.4 8.6 0.0 2.3 1 1 1 2 2 2 0 Pentapeptide repeats (8 copies) Ank_2 PF12796.7 KFR02590.1 - 0.0071 16.9 0.0 0.029 14.9 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) PH_16 PF17838.1 KFR02591.1 - 4.2e-40 136.5 1.5 6.3e-40 135.9 0.4 2.0 2 0 0 2 2 2 1 PH domain RhoGEF PF00621.20 KFR02591.1 - 5.1e-31 108.3 6.9 5.1e-31 108.3 6.9 3.0 3 1 0 3 3 3 1 RhoGEF domain C1_1 PF00130.22 KFR02591.1 - 5.5e-05 23.0 7.7 0.00011 22.0 7.7 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 KFR02591.1 - 0.0001 22.8 0.0 0.0001 22.8 0.0 2.8 3 0 0 3 3 3 1 PH domain C1_2 PF03107.16 KFR02591.1 - 0.019 15.3 4.1 0.042 14.2 4.1 1.6 1 0 0 1 1 1 0 C1 domain Prok-RING_1 PF14446.6 KFR02591.1 - 0.17 11.8 6.2 0.41 10.6 6.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 KFR02591.1 - 0.22 11.2 6.0 0.45 10.2 6.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type CBF PF03914.17 KFR02591.1 - 2.3 8.2 7.5 0.39 10.7 0.1 3.2 3 0 0 3 3 3 0 CBF/Mak21 family DZR PF12773.7 KFR02591.1 - 3.9 7.6 6.4 13 5.9 6.4 1.8 1 0 0 1 1 1 0 Double zinc ribbon Kelch_1 PF01344.25 KFR02592.1 - 6.1e-51 169.8 10.6 7.7e-12 44.6 0.2 6.0 6 1 0 6 6 6 5 Kelch motif BACK PF07707.15 KFR02592.1 - 1.6e-33 114.8 3.5 1.8e-33 114.7 2.0 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFR02592.1 - 7.6e-29 99.0 4.3 4.3e-06 26.8 0.0 6.2 3 2 3 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KFR02592.1 - 7e-28 96.3 1.8 1.1e-05 25.6 0.0 6.3 6 1 0 6 6 6 5 Galactose oxidase, central domain BTB PF00651.31 KFR02592.1 - 6e-26 90.9 0.3 1.2e-25 89.8 0.1 1.7 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 KFR02592.1 - 2.4e-24 84.3 6.3 0.00016 21.5 0.1 6.3 5 1 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 KFR02592.1 - 3.6e-22 78.1 1.1 7e-08 32.4 0.0 5.7 4 2 1 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KFR02592.1 - 1.1e-13 50.8 3.3 9.1e-07 28.7 0.0 5.5 5 0 0 5 5 5 2 Kelch motif DUF1668 PF07893.13 KFR02592.1 - 0.006 16.0 0.2 0.035 13.5 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1668) DUF3342 PF11822.8 KFR02592.1 - 0.0082 16.3 0.0 0.035 14.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) Pepdidase_M14_N PF18027.1 KFR02593.1 - 3.2e-11 43.6 0.4 7.3e-11 42.4 0.4 1.7 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 KFR02593.1 - 6e-11 42.7 0.0 1e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 KFR02593.1 - 0.052 12.6 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Pkinase_Tyr PF07714.17 KFR02594.1 - 2.6e-90 302.2 0.1 4.8e-53 180.1 0.0 2.1 1 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFR02594.1 - 1.6e-43 149.0 0.0 3.7e-43 147.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain TPKR_C2 PF16920.5 KFR02594.1 - 4.5e-21 74.7 6.0 1.4e-20 73.2 6.0 1.9 1 0 0 1 1 1 1 Tyrosine-protein kinase receptor C2 Ig-like domain Ig_3 PF13927.6 KFR02594.1 - 1.2e-13 51.4 0.0 1.5e-05 25.5 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFR02594.1 - 3.4e-13 49.5 0.0 1.2e-06 28.5 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFR02594.1 - 5.4e-09 36.1 0.1 8.2e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFR02594.1 - 2.4e-07 31.0 0.1 0.038 14.3 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFR02594.1 - 0.0014 18.6 0.0 0.51 10.4 0.0 2.5 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain TrkA_TMD PF18613.1 KFR02594.1 - 0.0085 15.5 11.6 0.018 14.4 11.6 1.6 1 0 0 1 1 1 1 Tyrosine kinase receptor A trans-membrane domain LRR_8 PF13855.6 KFR02594.1 - 0.014 15.2 1.0 0.027 14.2 1.0 1.5 1 0 0 1 1 1 0 Leucine rich repeat Haspin_kinase PF12330.8 KFR02594.1 - 0.082 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Ribosomal_S11 PF00411.19 KFR02595.1 - 6.8e-28 97.3 2.5 9.7e-28 96.8 2.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 Det1 PF09737.9 KFR02596.1 - 2.6e-193 642.7 0.9 3.1e-193 642.4 0.9 1.1 1 0 0 1 1 1 1 De-etiolated protein 1 Det1 RNase_T PF00929.24 KFR02597.1 - 9.7e-18 65.2 0.0 1.5e-17 64.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KFR02597.1 - 4.6e-05 23.2 0.0 0.00012 21.8 0.0 1.6 1 1 0 1 1 1 1 3'-5' exonuclease Xlink PF00193.17 KFR02598.1 - 6.1e-123 401.5 13.8 2e-32 111.4 0.4 5.3 5 0 0 5 5 5 4 Extracellular link domain Lectin_C PF00059.21 KFR02598.1 - 4.9e-22 78.7 15.2 1.6e-19 70.6 2.3 5.1 5 0 0 5 5 5 2 Lectin C-type domain V-set PF07686.17 KFR02598.1 - 8.5e-10 38.8 0.0 2.1e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin V-set domain CTD PF12815.7 KFR02598.1 - 6.6e-09 36.2 20.2 0.12 12.9 0.7 7.3 1 1 4 6 6 6 4 Spt5 C-terminal nonapeptide repeat binding Spt4 Sushi PF00084.20 KFR02598.1 - 6.9e-09 36.2 1.7 6.9e-09 36.2 1.7 2.0 2 0 0 2 2 1 1 Sushi repeat (SCR repeat) EGF PF00008.27 KFR02598.1 - 3.6e-06 27.2 4.0 1.2e-05 25.5 4.0 2.0 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 KFR02598.1 - 3.8e-05 24.2 1.4 3.8e-05 24.2 1.4 2.9 4 0 0 4 4 4 1 Human growth factor-like EGF Pentapeptide_4 PF13599.6 KFR02598.1 - 0.0098 16.0 0.0 9.3 6.5 0.0 4.7 4 2 2 6 6 6 1 Pentapeptide repeats (9 copies) EGF_CA PF07645.15 KFR02598.1 - 0.039 14.2 8.5 0.079 13.2 6.9 2.5 2 1 0 2 2 2 0 Calcium-binding EGF domain Chordopox_A33R PF05966.12 KFR02598.1 - 0.076 12.3 2.8 8.8 5.6 0.1 4.0 5 0 0 5 5 5 0 Chordopoxvirus A33R protein DUF273 PF03314.14 KFR02598.1 - 0.14 11.7 0.0 58 3.1 0.0 3.8 3 1 0 4 4 4 0 Protein of unknown function, DUF273 UL45 PF05473.12 KFR02598.1 - 0.16 11.6 0.9 0.5 10.0 0.9 1.8 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Xlink PF00193.17 KFR02599.1 - 1.5e-63 211.2 0.0 1.8e-33 114.8 0.0 2.2 2 0 0 2 2 2 2 Extracellular link domain V-set PF07686.17 KFR02599.1 - 9.8e-12 45.0 0.0 1.7e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFR02599.1 - 3.7e-07 30.2 0.0 5.8e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFR02599.1 - 2.6e-05 24.7 0.0 5.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFR02599.1 - 0.00024 21.1 0.0 0.00052 20.0 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain Lectin_C PF00059.21 KFR02599.1 - 0.0024 18.6 0.1 0.69 10.7 0.0 2.3 2 0 0 2 2 2 1 Lectin C-type domain Izumo-Ig PF16706.5 KFR02599.1 - 0.0048 16.9 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Izumo-like Immunoglobulin domain Ig_2 PF13895.6 KFR02599.1 - 0.018 15.4 0.0 0.19 12.1 0.0 2.2 1 1 0 1 1 1 0 Immunoglobulin domain F5_F8_type_C PF00754.25 KFR02600.1 - 3.3e-60 201.8 1.5 6.1e-31 107.2 2.1 2.1 2 0 0 2 2 2 2 F5/8 type C domain EGF PF00008.27 KFR02600.1 - 2.4e-21 75.7 44.4 1e-08 35.3 7.8 3.8 4 0 0 4 4 4 3 EGF-like domain hEGF PF12661.7 KFR02600.1 - 1.2e-08 35.2 40.4 0.0002 21.9 6.6 4.4 4 0 0 4 4 4 3 Human growth factor-like EGF EGF_2 PF07974.13 KFR02600.1 - 1.5e-08 34.8 40.9 0.0099 16.2 8.7 3.5 3 0 0 3 3 3 3 EGF-like domain EGF_3 PF12947.7 KFR02600.1 - 0.47 10.7 32.7 0.55 10.5 8.5 4.2 1 1 2 3 3 3 0 EGF domain Abhydrolase_1 PF00561.20 KFR02601.1 - 5.7e-26 91.7 0.0 7.6e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFR02601.1 - 4.2e-11 42.6 0.0 1e-10 41.3 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFR02601.1 - 0.0039 17.8 0.0 0.0067 17.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 KFR02601.1 - 0.0039 17.2 0.1 0.011 15.7 0.1 1.6 1 1 0 1 1 1 1 Cutinase Peptidase_S9 PF00326.21 KFR02601.1 - 0.0064 16.0 0.2 0.38 10.2 0.1 2.8 2 1 1 3 3 3 1 Prolyl oligopeptidase family DUF915 PF06028.11 KFR02601.1 - 0.0099 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) DUF2637 PF10935.8 KFR02601.1 - 0.013 15.4 0.0 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2637) VirJ PF06057.11 KFR02601.1 - 0.046 13.6 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF5464 PF17552.2 KFR02601.1 - 0.18 12.1 1.4 1.1 9.5 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5464) CRAL_TRIO PF00650.20 KFR02602.1 - 7.3e-39 133.0 0.0 1.1e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFR02602.1 - 1.1e-10 41.8 0.0 2e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFR02602.1 - 1.9e-06 28.0 0.2 6.5e-06 26.2 0.2 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF1336 PF07059.12 KFR02602.1 - 0.045 13.8 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1336) DUF2383 PF09537.10 KFR02602.1 - 0.083 13.2 0.3 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Spc7 PF08317.11 KFR02602.1 - 0.086 11.7 1.2 0.15 10.9 1.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein FANCI_HD2 PF14680.6 KFR02603.1 - 9.4e-98 326.2 4.4 9.4e-98 326.2 4.4 2.1 2 0 0 2 2 2 1 FANCI helical domain 2 FANCI_S4 PF14678.6 KFR02603.1 - 6.9e-94 313.6 4.6 6.9e-94 313.6 4.6 3.2 5 0 0 5 5 5 1 FANCI solenoid 4 FANCI_S3 PF14677.6 KFR02603.1 - 3.8e-83 278.4 3.8 3.8e-83 278.4 3.8 3.4 4 0 0 4 4 4 1 FANCI solenoid 3 FANCI_S1 PF14675.6 KFR02603.1 - 2.3e-80 269.3 0.6 1e-79 267.2 0.6 2.2 1 0 0 1 1 1 1 FANCI solenoid 1 FANCI_S2 PF14676.6 KFR02603.1 - 1.7e-60 204.1 3.8 4.7e-60 202.6 0.2 3.5 3 0 0 3 3 3 1 FANCI solenoid 2 FANCI_HD1 PF14679.6 KFR02603.1 - 1.9e-31 107.9 0.4 9.4e-31 105.6 0.4 2.4 1 0 0 1 1 1 1 FANCI helical domain 1 FANCI_S1-cap PF14674.6 KFR02603.1 - 5.4e-09 36.0 0.3 3.4e-08 33.4 0.3 2.6 1 0 0 1 1 1 1 FANCI solenoid 1 cap DNApol_Exo PF18136.1 KFR02604.1 - 1.8e-105 352.1 0.0 2.9e-105 351.5 0.0 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KFR02604.1 - 1.1e-59 202.4 0.0 1.9e-59 201.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 KFR02604.1 - 0.053 13.2 0.1 0.42 10.3 0.1 2.1 1 1 0 1 1 1 0 3'-5' exonuclease Ammonium_transp PF00909.21 KFR02605.1 - 1.4e-76 257.8 20.9 1.9e-76 257.4 20.9 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family DUF4293 PF14126.6 KFR02605.1 - 0.059 13.6 2.9 0.14 12.4 1.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) Treslin_N PF15292.6 KFR02606.1 - 1.1e-264 880.7 8.0 1.2e-264 880.5 8.0 1.0 1 0 0 1 1 1 1 Treslin N-terminus Kinesin PF00225.23 KFR02608.1 - 1.7e-78 263.9 0.1 1.7e-78 263.9 0.1 3.2 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KFR02608.1 - 0.0075 16.2 0.0 0.0075 16.2 0.0 3.3 2 1 0 2 2 2 1 Microtubule binding Ras PF00071.22 KFR02609.1 - 4.6e-18 65.3 0.0 5.2e-18 65.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR02609.1 - 0.0019 18.4 0.0 0.0022 18.2 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR02609.1 - 0.039 13.4 0.0 0.065 12.7 0.0 1.4 1 1 0 1 1 1 0 ADP-ribosylation factor family Perilipin PF03036.16 KFR02610.1 - 3.8e-54 184.2 0.5 4.2e-54 184.1 0.5 1.0 1 0 0 1 1 1 1 Perilipin family PEX11 PF05648.14 KFR02611.1 - 4.7e-63 212.6 0.3 5.3e-63 212.5 0.3 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Herpes_UL55 PF04537.12 KFR02611.1 - 0.0037 17.3 0.0 0.0067 16.4 0.0 1.4 1 0 0 1 1 1 1 Herpesvirus UL55 protein MCC-bdg_PDZ PF10506.9 KFR02611.1 - 0.077 13.0 0.2 0.17 11.9 0.2 1.5 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome UPF0258 PF06789.12 KFR02613.1 - 2.1e-60 203.2 0.2 4.8e-60 202.1 0.2 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0258) RXT2_N PF08595.11 KFR02613.1 - 0.0067 16.5 0.4 0.0067 16.5 0.4 2.2 2 0 0 2 2 2 1 RXT2-like, N-terminal 5-FTHF_cyc-lig PF01812.20 KFR02614.1 - 9.4e-50 169.1 0.0 1e-49 168.9 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Stonin2_N PF12016.8 KFR02614.1 - 0.18 11.2 0.0 0.23 10.9 0.0 1.1 1 0 0 1 1 1 0 Stonin 2 Bcl-2 PF00452.19 KFR02615.1 - 1.1e-21 77.3 0.0 2e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family zf-A20 PF01754.16 KFR02616.1 - 8.3e-13 48.0 8.7 2.5e-12 46.5 8.7 1.9 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.16 KFR02616.1 - 3.3e-09 36.8 7.5 3.3e-09 36.8 7.5 2.3 3 1 1 4 4 4 1 AN1-like Zinc finger IQCJ-SCHIP1 PF15157.6 KFR02616.1 - 3.9 7.3 7.1 0.64 9.8 0.5 2.0 1 1 1 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif FAA_hydrolase PF01557.18 KFR02617.1 - 7.6e-57 192.5 0.0 1e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KFR02617.1 - 2.6e-36 124.1 0.0 4.1e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal PAS_3 PF08447.12 KFR02618.1 - 1.6e-24 85.9 0.0 1.5e-18 66.8 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 KFR02618.1 - 1.9e-23 82.6 0.0 9.7e-14 51.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KFR02618.1 - 1.2e-21 76.9 0.6 1.3e-18 67.2 0.2 3.1 2 1 1 3 3 3 2 PAS domain HLH PF00010.26 KFR02618.1 - 3e-14 52.7 1.2 5.8e-14 51.8 1.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 KFR02618.1 - 8.9e-12 45.2 0.0 6.6e-09 36.0 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KFR02618.1 - 4.2e-05 23.8 0.0 0.13 12.5 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.11 KFR02618.1 - 0.015 16.0 0.0 0.19 12.4 0.0 2.3 2 0 0 2 2 2 0 PAS fold Hydrolase_4 PF12146.8 KFR02619.1 - 1.6e-13 50.5 0.0 2.6e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFR02619.1 - 1.3e-07 31.6 0.1 0.0071 16.0 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFR02619.1 - 1.6e-07 32.1 0.0 0.00014 22.6 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KFR02619.1 - 7.6e-07 28.8 0.0 2.6e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family UPF0227 PF05728.12 KFR02619.1 - 0.00076 19.5 0.0 0.014 15.4 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) DLH PF01738.18 KFR02619.1 - 0.00086 18.9 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF818 PF05677.12 KFR02619.1 - 0.0012 17.9 0.1 0.0018 17.3 0.1 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_5 PF12695.7 KFR02619.1 - 0.0025 17.6 0.0 0.0052 16.6 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 KFR02619.1 - 0.0057 16.3 0.0 0.0085 15.8 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Asp2 PF16929.5 KFR02619.1 - 0.0087 15.1 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Accessory Sec system GspB-transporter Abhydrolase_2 PF02230.16 KFR02619.1 - 0.0092 15.8 0.0 0.054 13.3 0.0 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase ILEI PF15711.5 KFR02620.1 - 6e-42 142.0 0.9 1.5e-24 86.3 0.0 3.4 3 0 0 3 3 3 2 Interleukin-like EMT inducer G8 PF10162.9 KFR02620.1 - 5.7e-28 97.5 0.1 1.2e-27 96.5 0.1 1.5 1 0 0 1 1 1 1 G8 domain Mucin2_WxxW PF13330.6 KFR02620.1 - 6.5e-15 55.7 0.4 3.5e-13 50.2 0.2 2.5 2 0 0 2 2 2 1 Mucin-2 protein WxxW repeating region Beta_helix PF13229.6 KFR02620.1 - 0.0069 16.2 2.0 1.9 8.3 1.2 4.2 2 1 1 3 3 3 1 Right handed beta helix region Mesd PF10185.9 KFR02621.1 - 5.6e-67 224.5 0.2 6.8e-67 224.2 0.2 1.1 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor PSII_BNR PF14870.6 KFR02621.1 - 0.023 14.0 0.0 0.057 12.7 0.0 1.6 1 1 1 2 2 2 0 Photosynthesis system II assembly factor YCF48 DUF3391 PF11871.8 KFR02621.1 - 0.03 14.9 0.2 0.042 14.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) PDZ PF00595.24 KFR02624.1 - 2.9e-30 104.5 0.2 2.1e-18 66.5 0.1 3.1 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 KFR02624.1 - 7.3e-17 61.0 0.0 8.7e-09 35.1 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFR02624.1 - 2.7e-08 34.0 0.0 0.00091 19.5 0.0 2.6 2 1 0 2 2 2 2 PDZ domain PDZ_4 PF17816.1 KFR02624.1 - 0.027 14.8 0.0 10 6.5 0.0 2.3 2 0 0 2 2 2 0 PDZ domain PDZ PF00595.24 KFR02625.1 - 8.2e-24 83.8 0.7 3.7e-13 49.6 0.4 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFR02625.1 - 6.4e-11 41.9 0.1 2.2e-08 33.8 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFR02625.1 - 3.4e-07 30.5 0.6 0.00024 21.4 0.3 3.0 2 1 0 2 2 2 2 PDZ domain DUF5315 PF17242.2 KFR02625.1 - 0.12 12.3 0.2 1 9.2 0.1 2.4 2 0 0 2 2 2 0 Disordered region of unknown function (DUF5315) START PF01852.19 KFR02626.1 - 1.4e-18 67.1 0.0 1.5e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 START domain GTP_EFTU PF00009.27 KFR02627.1 - 2.3e-60 203.5 0.0 1.1e-59 201.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KFR02627.1 - 4.9e-18 65.0 0.0 2e-17 63.0 0.0 2.1 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KFR02627.1 - 7.3e-09 35.6 0.2 2.3e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KFR02627.1 - 1.2e-08 35.2 0.0 5.2e-08 33.2 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 KFR02627.1 - 0.00035 20.3 0.0 0.0039 17.0 0.0 2.6 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 KFR02627.1 - 0.01 15.9 0.0 0.035 14.2 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase SSXT PF05030.12 KFR02627.1 - 0.055 13.1 0.8 0.14 11.8 0.8 1.7 1 0 0 1 1 1 0 SSXT protein (N-terminal region) G-alpha PF00503.20 KFR02627.1 - 0.073 12.2 1.1 3.5 6.7 0.0 3.1 3 0 0 3 3 3 0 G-protein alpha subunit DUF4633 PF15464.6 KFR02627.1 - 0.76 9.9 4.4 3 8.0 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4633) TSP_1 PF00090.19 KFR02629.1 - 9.3e-57 189.1 158.0 1.3e-06 28.5 3.2 14.9 14 1 0 14 14 14 12 Thrombospondin type 1 domain I-set PF07679.16 KFR02629.1 - 1.4e-27 95.6 0.2 7.6e-14 51.6 0.0 4.2 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR02629.1 - 2.6e-26 92.0 2.3 5.5e-12 46.1 0.0 4.3 3 1 1 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.6 KFR02629.1 - 1e-21 77.0 1.2 5.6e-10 39.4 0.0 4.8 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 KFR02629.1 - 6.5e-16 58.3 0.1 7.5e-10 38.8 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFR02629.1 - 9.8e-11 41.8 2.0 0.00089 19.4 0.0 5.1 4 1 1 5 5 5 2 Immunoglobulin V-set domain PLAC PF08686.11 KFR02629.1 - 3e-09 37.5 13.3 2.5e-08 34.5 13.3 2.8 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain ADAM_spacer1 PF05986.14 KFR02629.1 - 0.0011 19.0 0.0 0.0023 17.9 0.0 1.6 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Izumo-Ig PF16706.5 KFR02629.1 - 0.045 13.8 0.0 13 5.9 0.0 2.8 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Filament PF00038.21 KFR02630.1 - 9.6e-61 206.1 44.7 1.4e-60 205.6 44.7 1.2 1 0 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 KFR02630.1 - 1.7e-17 63.7 0.0 3.7e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Lamin Tail Domain GIT_CC PF16559.5 KFR02630.1 - 0.35 10.8 10.1 0.95 9.4 1.2 3.5 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Fez1 PF06818.15 KFR02630.1 - 9.9 6.6 45.1 2.5 8.5 22.2 2.8 1 1 2 3 3 3 0 Fez1 BAR PF03114.18 KFR02631.1 - 3e-73 246.4 6.9 3.6e-73 246.1 6.9 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KFR02631.1 - 9.2e-15 54.0 0.1 2.9e-14 52.4 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFR02631.1 - 1.3e-13 50.3 0.0 3.7e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFR02631.1 - 1.9e-13 50.0 0.1 3.1e-13 49.3 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.9 KFR02631.1 - 9.8e-08 31.5 3.4 3.2e-06 26.5 1.2 2.1 2 0 0 2 2 2 2 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 KFR02631.1 - 0.00021 21.1 5.1 0.0031 17.2 5.0 2.4 1 1 0 1 1 1 1 BAR domain of APPL family DUF4423 PF14394.6 KFR02631.1 - 0.11 12.2 1.4 0.38 10.5 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) PARP_reg PF02877.14 KFR02631.1 - 0.24 11.5 2.8 0.31 11.1 0.6 2.2 2 1 0 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain Csm2_III-A PF03750.13 KFR02631.1 - 0.4 11.5 3.2 0.38 11.6 0.7 2.2 2 0 0 2 2 2 0 Csm2 Type III-A zf-met PF12874.7 KFR02632.1 - 8e-11 42.0 22.0 0.0018 18.6 1.1 5.5 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KFR02632.1 - 1.7e-07 31.3 41.3 0.0038 17.6 2.3 7.5 6 1 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFR02632.1 - 3.9e-07 30.2 20.3 0.011 15.9 1.3 4.6 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KFR02632.1 - 3.6e-05 24.2 49.9 0.0044 17.7 1.6 8.5 10 0 0 10 10 10 3 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KFR02632.1 - 0.051 13.7 10.4 1.6 8.8 0.3 4.0 4 0 0 4 4 4 0 Aberrant zinc-finger zf-DNA_Pol PF08996.10 KFR02632.1 - 0.37 10.5 14.0 0.24 11.1 1.2 3.5 3 0 0 3 3 3 0 DNA Polymerase alpha zinc finger PWWP PF00855.17 KFR02633.1 - 0.00028 21.2 0.0 0.00028 21.2 0.0 2.5 2 1 0 2 2 2 1 PWWP domain Raftlin PF15250.6 KFR02633.1 - 4.5 5.9 12.4 5.9 5.5 12.4 1.0 1 0 0 1 1 1 0 Raftlin DUF2781 PF10914.8 KFR02634.1 - 5.2e-21 75.6 3.6 5.2e-21 75.6 3.6 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF2781) PHR PF08005.12 KFR02635.1 - 2.4e-50 171.1 0.8 3.4e-50 170.6 0.8 1.2 1 0 0 1 1 1 1 PHR domain BACK PF07707.15 KFR02635.1 - 8.9e-10 38.6 0.2 1.4e-08 34.8 0.1 2.6 1 1 1 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 KFR02635.1 - 1.1e-06 28.8 0.3 3.5e-05 24.0 0.0 2.5 1 1 1 2 2 2 1 BTB/POZ domain DUF167 PF02594.16 KFR02636.1 - 8.6e-20 70.6 0.8 1e-19 70.4 0.8 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 RAM PF15320.6 KFR02637.1 - 2.4e-20 72.9 1.8 2.6e-20 72.8 1.8 1.0 1 0 0 1 1 1 1 mRNA cap methylation, RNMT-activating mini protein WH1 PF00568.23 KFR02638.1 - 3.4e-36 123.6 0.4 7.9e-36 122.4 0.4 1.6 1 0 0 1 1 1 1 WH1 domain Macoilin PF09726.9 KFR02638.1 - 4.7e-06 25.5 24.6 5.4e-06 25.3 24.6 1.1 1 0 0 1 1 1 1 Macoilin family GAS PF13851.6 KFR02638.1 - 8.2e-05 22.0 44.1 0.00044 19.7 15.9 3.7 2 1 2 4 4 4 3 Growth-arrest specific micro-tubule binding DMPK_coil PF08826.10 KFR02638.1 - 9.5e-05 22.4 3.5 9.5e-05 22.4 3.5 3.8 2 1 1 3 3 3 1 DMPK coiled coil domain like MAD PF05557.13 KFR02638.1 - 0.0002 19.9 41.3 0.0019 16.7 20.4 2.1 1 1 1 2 2 2 2 Mitotic checkpoint protein IFT57 PF10498.9 KFR02638.1 - 0.00029 20.0 25.5 0.00043 19.4 25.5 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Uso1_p115_C PF04871.13 KFR02638.1 - 0.0013 19.1 16.8 0.0013 19.1 16.8 3.3 1 1 2 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region ATG16 PF08614.11 KFR02638.1 - 0.0026 18.0 49.3 0.0049 17.1 20.9 3.1 1 1 2 3 3 3 3 Autophagy protein 16 (ATG16) DUF4201 PF13870.6 KFR02638.1 - 0.0048 16.6 6.5 0.0048 16.6 6.5 3.2 2 1 1 3 3 2 2 Domain of unknown function (DUF4201) BST2 PF16716.5 KFR02638.1 - 0.0055 17.3 9.4 0.0055 17.3 9.4 4.1 2 1 2 4 4 3 1 Bone marrow stromal antigen 2 TMF_DNA_bd PF12329.8 KFR02638.1 - 0.01 15.8 10.0 0.01 15.8 10.0 3.9 2 1 2 4 4 3 1 TATA element modulatory factor 1 DNA binding HemX PF04375.14 KFR02638.1 - 0.011 15.1 10.3 0.011 15.1 10.3 3.4 1 1 2 3 3 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase TolA_bind_tri PF16331.5 KFR02638.1 - 0.011 15.7 23.5 0.19 11.8 7.7 3.8 1 1 2 3 3 3 0 TolA binding protein trimerisation Phage_GP20 PF06810.11 KFR02638.1 - 0.012 15.5 9.5 0.012 15.5 9.5 3.7 2 1 2 4 4 3 0 Phage minor structural protein GP20 CALCOCO1 PF07888.11 KFR02638.1 - 0.012 14.5 35.8 0.06 12.2 15.5 2.7 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like TMF_TATA_bd PF12325.8 KFR02638.1 - 0.012 15.8 9.6 0.012 15.8 9.6 3.1 2 1 1 3 3 2 0 TATA element modulatory factor 1 TATA binding FlaC_arch PF05377.11 KFR02638.1 - 0.018 15.4 22.9 1.9 8.9 0.7 4.9 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) Effector_1 PF04518.12 KFR02638.1 - 0.02 14.0 0.9 0.02 14.0 0.9 3.0 1 1 2 3 3 3 0 Effector from type III secretion system FPP PF05911.11 KFR02638.1 - 0.037 12.2 43.9 0.046 11.9 29.0 2.2 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DHR10 PF18595.1 KFR02638.1 - 0.081 13.0 51.3 0.081 13.0 9.1 4.0 2 1 2 4 4 4 0 Designed helical repeat protein 10 domain Fez1 PF06818.15 KFR02638.1 - 0.22 11.9 39.9 0.087 13.3 9.5 3.1 1 1 2 3 3 3 0 Fez1 Laminin_II PF06009.12 KFR02638.1 - 0.22 11.5 23.9 0.13 12.3 7.7 3.0 2 1 1 3 3 3 0 Laminin Domain II T3SSipB PF16535.5 KFR02638.1 - 0.26 11.8 25.1 0.6 10.6 18.4 3.0 2 1 1 3 3 3 0 Type III cell invasion protein SipB Sec34 PF04136.15 KFR02638.1 - 0.28 11.1 24.8 0.14 12.0 3.1 3.4 3 1 1 4 4 4 0 Sec34-like family CENP-H PF05837.12 KFR02638.1 - 0.29 11.5 43.6 0.094 13.1 11.1 4.1 2 1 3 5 5 5 0 Centromere protein H (CENP-H) DUF3450 PF11932.8 KFR02638.1 - 0.31 10.3 34.4 0.76 9.0 7.8 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF3450) HAP1_N PF04849.13 KFR02638.1 - 0.52 9.5 42.3 0.26 10.5 30.2 2.5 2 1 1 3 3 2 0 HAP1 N-terminal conserved region DUF948 PF06103.11 KFR02638.1 - 0.53 10.6 8.5 4.5 7.6 0.9 2.8 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 KFR02638.1 - 0.75 10.3 12.0 6.4 7.3 1.4 3.4 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.8 KFR02638.1 - 0.79 7.1 37.3 0.015 12.9 29.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) TACC_C PF05010.14 KFR02638.1 - 0.92 9.3 35.1 0.016 15.0 25.1 2.7 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF812 PF05667.11 KFR02638.1 - 0.93 8.3 40.9 0.86 8.4 22.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Prominin PF05478.11 KFR02638.1 - 0.99 7.3 18.2 3.3 5.5 17.9 1.8 1 1 0 1 1 1 0 Prominin FUSC PF04632.12 KFR02638.1 - 1 7.8 12.4 1 7.8 4.0 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family YabA PF06156.13 KFR02638.1 - 1.1 9.9 33.2 3.9 8.2 11.1 4.3 1 1 3 4 4 4 0 Initiation control protein YabA Leu_zip PF15294.6 KFR02638.1 - 1.2 8.6 34.6 0.039 13.5 25.2 2.3 1 1 1 2 2 2 0 Leucine zipper Filament PF00038.21 KFR02638.1 - 1.8 8.1 34.9 1.5 8.3 11.3 2.8 1 1 1 3 3 3 0 Intermediate filament protein MscS_porin PF12795.7 KFR02638.1 - 2 7.9 38.0 0.66 9.5 16.5 3.1 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Lebercilin PF15619.6 KFR02638.1 - 2.3 7.8 45.1 1.1 8.9 20.8 3.7 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease VGPC1_C PF16799.5 KFR02638.1 - 2.4 8.2 23.6 0.19 11.7 5.6 3.6 2 2 1 3 3 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 DUF1664 PF07889.12 KFR02638.1 - 2.4 8.2 22.6 4.5 7.3 6.6 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 KFR02638.1 - 2.7 8.4 26.5 0.33 11.3 2.8 3.7 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.9 KFR02638.1 - 2.8 7.9 48.5 0.55 10.2 2.0 4.1 2 1 1 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mod_r PF07200.13 KFR02638.1 - 3.1 7.9 39.6 2 8.5 21.5 3.1 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein TPR_MLP1_2 PF07926.12 KFR02638.1 - 3.1 7.9 52.9 0.12 12.5 6.1 4.1 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein ERM PF00769.19 KFR02638.1 - 3.2 7.5 51.0 0.4 10.4 39.1 2.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Spc7 PF08317.11 KFR02638.1 - 3.2 6.5 42.4 0.29 10.0 22.0 2.9 1 1 2 3 3 2 0 Spc7 kinetochore protein Cep57_CLD_2 PF14197.6 KFR02638.1 - 3.3 7.8 40.3 16 5.6 17.0 4.6 1 1 3 4 4 4 0 Centrosome localisation domain of PPC89 BRI3BP PF14965.6 KFR02638.1 - 3.3 7.2 12.5 2.4 7.6 1.0 3.0 2 2 2 4 4 4 0 Negative regulator of p53/TP53 APG6_N PF17675.1 KFR02638.1 - 4.3 7.9 50.9 0.19 12.2 7.7 3.6 1 1 2 3 3 2 0 Apg6 coiled-coil region ADIP PF11559.8 KFR02638.1 - 4.7 7.3 45.0 9.9 6.2 19.0 3.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding FH2 PF02181.23 KFR02638.1 - 6.7 5.7 24.3 12 4.9 2.5 3.7 2 1 2 4 4 4 0 Formin Homology 2 Domain FOXP-CC PF16159.5 KFR02638.1 - 7 7.4 12.6 0.47 11.1 2.3 3.2 1 1 2 3 3 3 0 FOXP coiled-coil domain Dor1 PF04124.12 KFR02638.1 - 7 5.2 25.2 0.48 9.1 18.7 2.0 2 1 1 3 3 2 0 Dor1-like family KASH_CCD PF14662.6 KFR02638.1 - 7.2 6.4 47.9 0.13 12.1 24.4 3.1 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH AIP3 PF03915.13 KFR02638.1 - 7.3 5.6 31.0 1.5 7.8 14.6 2.1 1 1 1 2 2 2 0 Actin interacting protein 3 DUF4200 PF13863.6 KFR02638.1 - 8 6.9 44.8 2.5 8.5 16.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) Jnk-SapK_ap_N PF09744.9 KFR02638.1 - 9.1 6.5 49.9 0.14 12.4 25.9 3.1 1 1 3 4 4 4 0 JNK_SAPK-associated protein-1 PRKG1_interact PF15898.5 KFR02638.1 - 9.2 7.2 44.2 1.9 9.4 2.7 4.4 1 1 2 4 4 3 0 cGMP-dependent protein kinase interacting domain DUF4600 PF15372.6 KFR02638.1 - 9.3 6.7 28.4 0.46 10.9 10.4 3.3 2 1 2 4 4 3 0 Domain of unknown function (DUF4600) EzrA PF06160.12 KFR02638.1 - 9.4 4.3 35.0 0.24 9.5 27.8 2.0 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA JMY PF15871.5 KFR02639.1 - 9.6e-117 390.3 25.6 9.6e-117 390.3 25.6 2.0 2 0 0 2 2 2 1 Junction-mediating and -regulatory protein WH2 PF02205.20 KFR02639.1 - 0.00062 19.5 0.2 0.0045 16.8 0.0 2.2 2 0 0 2 2 2 1 WH2 motif ZnuA PF01297.17 KFR02639.1 - 2.7 7.4 9.4 0.24 10.8 2.9 2.4 2 1 0 2 2 2 0 Zinc-uptake complex component A periplasmic Amidase PF01425.21 KFR02639.1 - 6.2 5.7 6.6 3.4 6.5 2.3 2.2 2 1 0 2 2 2 0 Amidase fn3 PF00041.21 KFR02640.1 - 1.5e-15 57.3 0.0 3.2e-10 40.2 0.0 2.8 2 0 0 2 2 2 2 Fibronectin type III domain SPRY PF00622.28 KFR02640.1 - 5.1e-12 46.0 0.1 1.4e-11 44.5 0.0 1.8 2 0 0 2 2 2 1 SPRY domain PRY PF13765.6 KFR02640.1 - 0.0075 15.9 0.0 0.042 13.5 0.0 2.3 2 0 0 2 2 2 1 SPRY-associated domain Pur_ac_phosph_N PF16656.5 KFR02640.1 - 0.038 14.5 0.0 0.23 12.1 0.0 2.3 2 1 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Bacillus_HBL PF05791.11 KFR02640.1 - 0.075 12.8 1.2 0.17 11.7 1.2 1.6 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF3552 PF12072.8 KFR02640.1 - 0.12 11.8 4.3 0.27 10.6 4.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF932 PF06067.11 KFR02640.1 - 0.23 11.2 1.8 0.48 10.1 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF932) SPX PF03105.19 KFR02640.1 - 1 9.2 10.7 1.5 8.7 10.7 1.2 1 0 0 1 1 1 0 SPX domain PDEase_I PF00233.19 KFR02641.1 - 1.8e-96 322.5 1.0 3.2e-96 321.7 1.0 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PAS PF00989.25 KFR02641.1 - 3.4e-12 46.3 0.0 1.1e-11 44.7 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KFR02641.1 - 3.8e-12 46.4 0.1 1e-11 45.0 0.1 1.8 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 KFR02641.1 - 3.4e-06 27.2 0.0 7.2e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KFR02641.1 - 1.5e-05 25.2 0.0 4.5e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 KFR02641.1 - 0.013 15.5 0.0 0.041 13.9 0.0 1.9 1 0 0 1 1 1 0 PAS domain Nrap_D2 PF17403.2 KFR02641.1 - 0.13 12.0 0.3 0.4 10.4 0.3 1.8 1 1 0 1 1 1 0 Nrap protein PAP/OAS-like domain Amidinotransf PF02274.17 KFR02642.1 - 1.2e-08 34.5 0.0 3.7e-05 23.0 0.0 3.3 3 1 0 3 3 3 3 Amidinotransferase AMP-binding PF00501.28 KFR02643.1 - 8.5e-45 153.1 0.0 1e-44 152.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFR02643.1 - 2.6e-06 28.3 0.0 5.3e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pyridoxal_deC PF00282.19 KFR02644.1 - 1.2e-166 554.1 0.0 1.5e-166 553.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KFR02644.1 - 0.0016 17.8 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KFR02644.1 - 0.032 13.4 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Ank_2 PF12796.7 KFR02645.1 - 2.9e-37 127.1 5.3 1.8e-15 57.3 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFR02645.1 - 3.3e-25 87.8 0.4 1.4e-09 38.0 0.1 4.8 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KFR02645.1 - 2.6e-24 84.5 0.5 9.1e-09 35.4 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KFR02645.1 - 1.3e-22 79.8 0.3 6.6e-10 39.3 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFR02645.1 - 1.7e-21 74.0 0.1 2.9e-06 27.2 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat AAA_23 PF13476.6 KFR02645.1 - 0.042 14.4 1.5 0.059 13.9 1.5 1.3 1 0 0 1 1 1 0 AAA domain LAMTOR5 PF16672.5 KFR02645.1 - 0.056 13.4 0.4 0.16 11.9 0.2 1.9 1 1 0 1 1 1 0 Ragulator complex protein LAMTOR5 DUF4265 PF14085.6 KFR02645.1 - 0.35 10.8 6.4 5.3 7.1 0.1 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4265) GrpE PF01025.19 KFR02645.1 - 1.1 8.9 10.1 3.2 7.4 10.1 1.8 1 0 0 1 1 1 0 GrpE TPD52 PF04201.15 KFR02645.1 - 1.4 8.6 6.4 2.7 7.6 6.4 1.4 1 0 0 1 1 1 0 Tumour protein D52 family UCH PF00443.29 KFR02646.1 - 8.3e-81 271.2 5.1 8.3e-81 271.2 5.1 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.11 KFR02646.1 - 1.7e-30 105.5 6.2 1.7e-30 105.5 6.2 2.6 2 0 0 2 2 2 1 USP8 dimerisation domain UCH_1 PF13423.6 KFR02646.1 - 1.5e-20 74.0 4.3 1.5e-20 74.0 4.3 2.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 KFR02646.1 - 2.4e-07 31.2 0.0 1.5e-06 28.7 0.0 2.5 1 0 0 1 1 1 1 Rhodanese-like domain Metallothio_Pro PF02069.16 KFR02646.1 - 0.13 12.5 0.7 0.37 11.1 0.5 1.9 2 0 0 2 2 2 0 Prokaryotic metallothionein UCH PF00443.29 KFR02647.1 - 1.8e-47 162.0 0.0 2e-47 161.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFR02647.1 - 3.7e-16 59.6 2.9 5.1e-16 59.2 2.9 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase NOB1_Zn_bind PF08772.11 KFR02647.1 - 1.3 9.2 8.1 0.34 11.1 1.8 2.8 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.7 KFR02647.1 - 1.8 8.6 7.7 23 5.1 5.3 2.7 2 1 0 2 2 2 0 Double zinc ribbon Peptidase_A22B PF04258.13 KFR02648.1 - 1.2e-81 274.3 19.5 1.8e-81 273.8 19.5 1.2 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.22 KFR02648.1 - 5e-07 29.6 0.0 9.9e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 PA domain Presenilin PF01080.17 KFR02648.1 - 0.0023 16.8 29.1 0.013 14.3 5.2 2.1 2 0 0 2 2 2 2 Presenilin AAA_18 PF13238.6 KFR02649.1 - 0.011 16.3 0.0 0.018 15.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pyr_redox_2 PF07992.14 KFR02650.1 - 1e-16 61.0 0.1 8.6e-11 41.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Tox-PL-2 PF15643.6 KFR02650.1 - 0.065 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Papain fold toxin 2 Snapin_Pallidin PF14712.6 KFR02651.1 - 3e-22 78.9 4.7 3.7e-22 78.6 4.7 1.1 1 0 0 1 1 1 1 Snapin/Pallidin DUF2353 PF09789.9 KFR02651.1 - 0.0044 16.4 1.2 0.0044 16.4 1.2 1.8 1 1 1 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) Med2 PF11214.8 KFR02651.1 - 0.037 14.2 1.7 0.047 13.9 1.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 2 PIN_4 PF13638.6 KFR02651.1 - 0.058 13.7 0.5 0.07 13.4 0.5 1.1 1 0 0 1 1 1 0 PIN domain Tup_N PF08581.10 KFR02651.1 - 0.34 11.2 5.2 0.91 9.9 0.6 2.1 1 1 1 2 2 2 0 Tup N-terminal Cation_efflux PF01545.21 KFR02652.1 - 1.2e-47 162.2 13.5 1.5e-47 162.0 13.5 1.1 1 0 0 1 1 1 1 Cation efflux family PHO4 PF01384.20 KFR02652.1 - 0.0008 18.5 2.3 0.00094 18.3 2.3 1.2 1 0 0 1 1 1 1 Phosphate transporter family DUF1282 PF06930.12 KFR02652.1 - 0.01 15.6 9.1 0.17 11.6 4.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1282) Polysacc_synt_C PF14667.6 KFR02652.1 - 0.016 15.3 3.1 0.016 15.3 3.1 2.0 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain DUF3119 PF11317.8 KFR02652.1 - 1.4 9.2 3.8 2.2 8.6 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3119) B12D PF06522.11 KFR02653.1 - 5.1e-23 80.7 0.0 5.8e-23 80.5 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DTW PF03942.15 KFR02655.1 - 2e-46 158.2 0.0 3.1e-46 157.6 0.0 1.3 1 0 0 1 1 1 1 DTW domain FGF PF00167.18 KFR02656.1 - 6.2e-49 165.2 1.9 8e-49 164.9 1.9 1.1 1 0 0 1 1 1 1 Fibroblast growth factor GalKase_gal_bdg PF10509.9 KFR02657.1 - 3e-24 84.3 0.0 5.8e-24 83.4 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KFR02657.1 - 1.7e-13 50.6 0.4 3.8e-13 49.5 0.4 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KFR02657.1 - 4.8e-13 49.3 0.0 1.6e-12 47.6 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal TPD52 PF04201.15 KFR02657.1 - 0.04 13.5 0.2 0.072 12.7 0.2 1.3 1 0 0 1 1 1 0 Tumour protein D52 family PCI PF01399.27 KFR02658.1 - 6.8e-26 90.8 1.8 6.8e-26 90.8 1.8 2.6 3 0 0 3 3 3 1 PCI domain DUF2087 PF09860.9 KFR02658.1 - 0.079 13.1 0.0 0.29 11.3 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) TPR_1 PF00515.28 KFR02658.1 - 0.15 11.9 3.0 7.7 6.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFR02658.1 - 0.17 12.1 2.5 20 5.6 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFR02658.1 - 0.21 11.7 5.1 74 3.7 0.0 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat FliS PF02561.14 KFR02658.1 - 0.55 10.5 6.9 0.55 10.5 4.1 2.5 2 1 0 2 2 2 0 Flagellar protein FliS Ribosomal_L7Ae PF01248.26 KFR02659.1 - 2.3e-22 78.6 0.1 7.3e-22 76.9 0.1 1.9 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF223 PF02721.14 KFR02659.1 - 0.14 12.5 0.1 2.5 8.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF223 PID PF00640.23 KFR02660.1 - 1.4e-45 154.7 0.0 2.6e-45 153.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.24 KFR02660.1 - 4.9e-16 58.6 0.0 1.9e-15 56.7 0.0 2.0 2 0 0 2 2 2 1 SH2 domain PTB PF08416.13 KFR02660.1 - 0.11 12.7 0.1 0.34 11.0 0.0 1.8 2 0 0 2 2 2 0 Phosphotyrosine-binding domain EGF_CA PF07645.15 KFR02661.1 - 0 1052.7 732.1 2e-11 43.9 7.1 48.6 49 1 1 50 50 50 44 Calcium-binding EGF domain cEGF PF12662.7 KFR02661.1 - 1.9e-208 673.5 414.0 5.3e-10 39.1 0.8 50.5 49 0 0 49 49 49 42 Complement Clr-like EGF-like TB PF00683.17 KFR02661.1 - 5.9e-117 381.2 149.2 2.9e-15 55.7 9.5 11.1 9 0 0 9 9 9 9 TB domain EGF PF00008.27 KFR02661.1 - 2.7e-111 363.2 699.6 0.00026 21.2 7.8 50.1 49 0 0 49 49 49 45 EGF-like domain hEGF PF12661.7 KFR02661.1 - 1.2e-103 336.7 655.6 0.00011 22.7 4.4 52.4 49 0 0 49 49 49 42 Human growth factor-like EGF FXa_inhibition PF14670.6 KFR02661.1 - 8.2e-100 326.8 727.0 4.2e-10 39.7 8.9 49.5 44 5 6 50 50 50 41 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 KFR02661.1 - 3.8e-58 193.4 621.5 1.6e-10 41.0 11.6 49.5 49 2 1 50 50 50 40 EGF domain Fibrillin_U_N PF18193.1 KFR02661.1 - 4.8e-16 58.6 7.4 4.8e-16 58.6 7.4 9.4 8 0 0 8 8 8 1 Fibrillin 1 unique N-terminal domain Plasmod_Pvs28 PF06247.11 KFR02661.1 - 3.5e-11 43.2 531.3 0.0047 17.2 6.0 45.7 42 3 3 45 45 45 27 Pvs28 EGF domain EGF_MSP1_1 PF12946.7 KFR02661.1 - 0.0053 16.8 7.4 0.0053 16.8 7.4 43.4 44 2 2 46 46 46 17 MSP1 EGF domain 1 dUTPase PF00692.19 KFR02662.1 - 3.4e-25 88.2 0.0 3.6e-25 88.1 0.0 1.0 1 0 0 1 1 1 1 dUTPase AA_permease PF00324.21 KFR02663.1 - 1.4e-151 505.4 39.1 1.7e-151 505.1 39.1 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KFR02663.1 - 1.1e-134 449.7 5.1 2.3e-98 330.1 1.9 2.2 1 1 1 2 2 2 2 Solute carrier family 12 AA_permease_N PF08403.10 KFR02663.1 - 1.6e-32 110.8 0.0 9.1e-31 105.2 0.1 2.6 2 0 0 2 2 2 1 Amino acid permease N-terminal AA_permease_2 PF13520.6 KFR02663.1 - 6e-22 78.1 44.1 9.6e-22 77.4 44.1 1.2 1 0 0 1 1 1 1 Amino acid permease Cortexin PF11057.8 KFR02664.1 - 8.7e-35 118.4 0.1 9.4e-35 118.3 0.1 1.0 1 0 0 1 1 1 1 Cortexin of kidney RRM_1 PF00076.22 KFR02665.1 - 2.2e-56 187.6 0.3 5.7e-19 67.7 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFR02665.1 - 1.6e-08 34.5 0.6 0.0046 17.0 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.8 KFR02665.1 - 3.3e-06 27.1 0.0 0.012 15.6 0.0 2.9 2 1 0 2 2 2 2 Limkain b1 RRM_5 PF13893.6 KFR02665.1 - 5.6e-05 22.7 0.0 0.074 12.7 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFR02665.1 - 0.0018 18.1 0.0 0.51 10.2 0.0 2.5 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 KFR02665.1 - 0.0037 17.1 0.1 18 5.1 0.0 3.7 3 1 1 4 4 4 1 Rrp7 RRM-like N-terminal domain DUF3932 PF13068.6 KFR02665.1 - 0.0073 16.6 0.0 1.5 9.1 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3932) DbpA PF03880.15 KFR02665.1 - 0.073 13.1 0.0 10 6.2 0.0 2.6 2 0 0 2 2 2 0 DbpA RNA binding domain DNA_topoisoIV PF00521.20 KFR02665.1 - 0.15 10.9 0.0 1.9 7.3 0.0 2.0 2 0 0 2 2 2 0 DNA gyrase/topoisomerase IV, subunit A Na_Ca_ex PF01699.24 KFR02666.1 - 3.4e-50 169.9 41.6 1.1e-27 96.9 18.5 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF2456 PF10445.9 KFR02666.1 - 0.7 10.0 6.5 0.76 9.9 1.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) SPC25 PF06703.11 KFR02666.1 - 2.5 7.9 8.6 0.23 11.3 1.2 2.3 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Sema PF01403.19 KFR02667.1 - 2.6e-133 444.9 0.0 4.8e-133 444.1 0.0 1.3 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 KFR02667.1 - 3e-05 24.5 3.1 7.6e-05 23.2 3.1 1.7 1 0 0 1 1 1 1 Plexin repeat ISP3_C PF18045.1 KFR02667.1 - 0.26 11.2 0.5 1.7 8.5 0.1 2.3 2 0 0 2 2 2 0 ISP3 C-terminal PP1_bind PF15276.6 KFR02667.1 - 3.1 8.2 6.9 2.5 8.5 0.7 2.9 2 0 0 2 2 2 0 Protein phosphatase 1 binding Rav1p_C PF12234.8 KFR02668.1 - 8.9e-84 282.1 0.2 1.3e-72 245.2 0.1 2.3 2 0 0 2 2 2 2 RAVE protein 1 C terminal WD40 PF00400.32 KFR02668.1 - 8.5e-14 51.7 26.9 0.0036 18.1 0.0 11.2 12 0 0 12 12 12 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR02668.1 - 1.6e-06 28.3 0.1 0.18 12.1 0.0 4.4 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFR02668.1 - 0.00032 20.6 0.5 1.8 8.4 0.0 4.0 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Opiods_neuropep PF01160.18 KFR02668.1 - 1.4 9.1 3.5 3.5 7.8 0.1 3.1 3 0 0 3 3 3 0 Vertebrate endogenous opioids neuropeptide OLF PF02191.16 KFR02669.1 - 6e-64 216.0 1.6 7.1e-64 215.7 1.6 1.0 1 0 0 1 1 1 1 Olfactomedin-like domain Collagen PF01391.18 KFR02669.1 - 6.7e-17 61.0 63.9 3.9e-10 39.3 26.5 3.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) p450 PF00067.22 KFR02670.1 - 4e-104 349.0 0.2 4.7e-104 348.7 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF758 PF05527.11 KFR02671.1 - 1.4e-80 269.5 8.0 1.6e-80 269.4 8.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) Seadorna_VP6 PF07407.11 KFR02671.1 - 0.02 13.9 1.6 0.024 13.6 0.5 1.4 1 1 0 1 1 1 0 Seadornavirus VP6 protein RPAP3_C PF13877.6 KFR02671.1 - 0.02 15.4 1.8 0.038 14.5 0.7 1.9 2 1 0 2 2 2 0 Potential Monad-binding region of RPAP3 Rsd_AlgQ PF04353.13 KFR02671.1 - 0.026 14.5 4.2 0.89 9.5 2.4 2.2 1 1 1 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ CdvA PF18822.1 KFR02671.1 - 0.046 13.6 1.5 0.046 13.6 1.5 2.1 1 1 1 2 2 2 0 CdvA-like coiled-coil domain DUF2408 PF10303.9 KFR02671.1 - 0.065 13.8 2.2 0.32 11.5 2.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DALR_1 PF05746.15 KFR02671.1 - 0.14 12.3 2.4 0.2 11.8 1.7 1.6 1 1 0 1 1 1 0 DALR anticodon binding domain Mnd1 PF03962.15 KFR02671.1 - 4.1 7.8 6.8 5.8 7.3 0.0 3.5 4 1 1 5 5 5 0 Mnd1 HTH domain SGIII PF15467.6 KFR02672.1 - 2.7e-220 732.3 34.0 3e-220 732.2 34.0 1.0 1 0 0 1 1 1 1 Secretogranin-3 DUF2680 PF10925.8 KFR02672.1 - 0.00015 21.7 14.1 0.077 13.0 0.2 4.6 5 0 0 5 5 5 3 Protein of unknown function (DUF2680) DUF2201_N PF13203.6 KFR02672.1 - 1 8.9 6.2 0.47 10.0 1.8 2.3 2 0 0 2 2 2 0 Putative metallopeptidase domain LysM PF01476.20 KFR02673.1 - 1e-08 35.1 0.0 1.9e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 LysM domain Tropomodulin PF03250.14 KFR02674.1 - 3.5e-42 143.8 4.8 1.2e-41 142.0 1.2 2.6 3 0 0 3 3 3 1 Tropomodulin LRR_6 PF13516.6 KFR02674.1 - 0.097 12.8 0.1 0.097 12.8 0.1 2.9 3 0 0 3 3 3 0 Leucine Rich repeat Tropomodulin PF03250.14 KFR02675.1 - 4.3e-41 140.3 3.5 1.3e-40 138.7 3.5 1.9 1 1 0 1 1 1 1 Tropomodulin LRR_6 PF13516.6 KFR02675.1 - 0.006 16.6 1.4 0.019 15.0 0.1 2.7 2 0 0 2 2 2 1 Leucine Rich repeat Secretogranin_V PF05281.11 KFR02675.1 - 0.079 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) LRR_4 PF12799.7 KFR02675.1 - 1.1 9.8 5.6 3.8 8.1 0.2 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Leo1 PF04004.13 KFR02676.1 - 4.6e-54 182.7 0.0 4.6e-54 182.7 0.0 3.3 2 1 0 2 2 2 1 Leo1-like protein Pkinase PF00069.25 KFR02677.1 - 3.2e-70 236.5 0.0 4.8e-70 235.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR02677.1 - 1.2e-25 90.3 0.0 2.2e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFR02677.1 - 0.0063 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family WD40 PF00400.32 KFR02678.1 - 9e-36 121.3 22.0 3.6e-07 30.8 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR02678.1 - 1.7e-13 50.7 0.1 0.057 13.7 0.0 5.4 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFR02678.1 - 1.7e-05 24.3 0.1 0.62 9.3 0.0 4.0 2 1 2 4 4 4 2 WD40-like domain DIL PF01843.19 KFR02679.1 - 2.1e-28 98.6 1.3 2.1e-28 98.6 1.3 3.3 3 0 0 3 3 3 1 DIL domain IQ PF00612.27 KFR02679.1 - 0.00039 20.0 2.4 0.0015 18.1 2.4 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif Csm1_N PF18504.1 KFR02679.1 - 0.022 15.1 2.9 0.022 15.1 2.9 9.3 5 2 4 9 9 9 0 Csm1 N-terminal domain Myosin_head PF00063.21 KFR02680.1 - 1.2e-269 896.3 14.7 1.4e-269 896.0 14.7 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 KFR02680.1 - 5.7e-18 63.0 28.4 6.8e-06 25.4 0.8 4.8 4 0 0 4 4 4 4 IQ calmodulin-binding motif Myosin_N PF02736.19 KFR02680.1 - 8.1e-05 22.4 0.0 0.00019 21.2 0.0 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 KFR02680.1 - 0.0063 16.8 0.1 0.025 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFR02680.1 - 0.013 15.9 0.0 0.059 13.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 KFR02680.1 - 0.078 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 KFR02680.1 - 0.079 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain PRK PF00485.18 KFR02680.1 - 0.083 12.6 0.3 0.34 10.6 0.5 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Myosin_head PF00063.21 KFR02681.1 - 4.8e-289 960.3 5.0 5.7e-289 960.1 5.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 KFR02681.1 - 9.9e-18 62.2 32.7 7.8e-05 22.1 3.8 4.7 4 0 0 4 4 4 4 IQ calmodulin-binding motif AAA_22 PF13401.6 KFR02681.1 - 0.012 15.9 0.0 0.035 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Myosin_N PF02736.19 KFR02681.1 - 0.013 15.3 0.5 0.027 14.3 0.2 1.8 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 KFR02681.1 - 0.02 15.3 0.0 0.053 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 KFR02681.1 - 0.14 11.2 0.0 0.29 10.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Endosulfine PF04667.17 KFR02682.1 - 6.9e-11 42.1 1.0 9.2e-11 41.7 1.0 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Ntox30 PF15532.6 KFR02682.1 - 0.058 13.8 0.0 0.071 13.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin 30 Chromosome_seg PF13889.6 KFR02683.1 - 2.4e-19 69.2 0.3 5.3e-19 68.1 0.3 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis DUF4210 PF13915.6 KFR02683.1 - 1.4e-13 51.2 0.1 5.5e-13 49.3 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Catalase-rel PF06628.12 KFR02683.1 - 0.16 12.2 0.3 27 5.1 0.0 2.8 3 0 0 3 3 3 0 Catalase-related immune-responsive CUT PF02376.15 KFR02684.1 - 9e-32 109.1 0.7 1.4e-31 108.5 0.7 1.3 1 0 0 1 1 1 1 CUT domain Homeodomain PF00046.29 KFR02684.1 - 2.8e-10 39.9 0.7 5.4e-10 39.0 0.7 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFR02684.1 - 0.00073 19.4 0.0 0.002 18.0 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain WD40 PF00400.32 KFR02685.1 - 5.6e-12 46.0 22.7 0.0038 18.0 0.4 8.5 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR02685.1 - 3.4e-05 24.1 2.9 0.07 13.4 0.0 5.4 5 2 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFR02685.1 - 0.00012 21.0 0.7 0.54 8.8 0.0 3.3 2 1 1 3 3 3 2 Nucleoporin Nup120/160 C2 PF00168.30 KFR02686.1 - 8.4e-07 29.2 0.0 1.1e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 C2 domain Ribosomal_L24e PF01246.20 KFR02687.1 - 8.8e-14 51.5 6.2 8.8e-14 51.5 6.2 2.1 2 0 0 2 2 2 1 Ribosomal protein L24e DUF1091 PF06477.13 KFR02687.1 - 0.063 13.8 0.7 0.095 13.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1091) Ras PF00071.22 KFR02688.1 - 1.6e-57 193.7 0.0 1.9e-57 193.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR02688.1 - 3.4e-31 107.9 0.0 5e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR02688.1 - 2.9e-12 46.4 0.0 4e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFR02688.1 - 0.00021 20.9 0.0 0.00049 19.7 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFR02688.1 - 0.00067 19.7 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFR02688.1 - 0.001 19.0 0.3 1.3 8.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 KFR02688.1 - 0.17 11.6 0.2 0.87 9.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain Glyco_transf_22 PF03901.17 KFR02689.1 - 8.2e-109 364.6 30.9 1.1e-108 364.1 30.9 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.6 KFR02689.1 - 1.2 9.3 15.2 0.036 14.3 6.2 2.2 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF2368 PF10166.9 KFR02689.1 - 2.3 7.8 4.4 3.4 7.3 0.6 2.4 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) HemX PF04375.14 KFR02690.1 - 0.00061 19.2 8.4 0.00061 19.2 8.4 3.8 1 1 2 3 3 3 1 HemX, putative uroporphyrinogen-III C-methyltransferase HbrB PF08539.11 KFR02690.1 - 0.11 12.5 0.2 0.11 12.5 0.2 3.0 3 0 0 3 3 3 0 HbrB-like DUF1664 PF07889.12 KFR02690.1 - 0.34 10.9 28.0 0.41 10.7 5.5 4.5 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) MTABC_N PF16185.5 KFR02690.1 - 0.47 9.9 1.8 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region SKA1 PF07160.12 KFR02690.1 - 0.53 10.1 0.0 0.53 10.1 0.0 6.0 3 1 2 5 5 5 0 Spindle and kinetochore-associated protein 1 ApoO PF09769.9 KFR02690.1 - 0.6 10.1 7.4 3.4 7.6 0.8 3.1 2 0 0 2 2 2 0 Apolipoprotein O DUF948 PF06103.11 KFR02690.1 - 2.7 8.3 8.4 8.5 6.7 0.2 3.7 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) YtxH PF12732.7 KFR02690.1 - 7.1 7.2 27.7 0.057 14.0 4.6 5.1 4 1 0 4 4 4 0 YtxH-like protein TPR_1 PF00515.28 KFR02691.1 - 4.8e-13 48.3 4.8 1.3e-05 24.8 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFR02691.1 - 6.8e-10 38.3 9.0 0.0021 18.1 0.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFR02691.1 - 1e-08 34.7 3.3 7.1e-05 22.4 0.7 2.8 3 0 0 3 3 3 2 TPR repeat TPR_9 PF13371.6 KFR02691.1 - 1.1e-06 28.7 0.1 0.029 14.5 0.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFR02691.1 - 6.8e-06 25.9 7.2 0.31 11.4 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFR02691.1 - 0.0016 18.7 9.7 0.2 12.0 0.3 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFR02691.1 - 0.0053 17.4 6.3 0.48 11.1 0.4 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFR02691.1 - 0.1 13.5 0.1 10 7.2 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat Apolipo_F PF15148.6 KFR02691.1 - 0.63 9.5 6.0 1.4 8.4 6.0 1.5 1 0 0 1 1 1 0 Apolipoprotein F DUF763 PF05559.11 KFR02691.1 - 0.68 9.1 8.5 1.1 8.4 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Glyco_transf_41 PF13844.6 KFR02691.1 - 0.7 8.2 4.9 1 7.7 4.9 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 41 TPR_17 PF13431.6 KFR02691.1 - 1.4 9.4 4.7 30 5.3 1.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat PHD PF00628.29 KFR02692.1 - 7.6e-07 28.9 5.7 1.3e-06 28.2 5.7 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 KFR02692.1 - 0.0025 17.7 1.1 0.0058 16.5 1.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 KFR02692.1 - 0.056 13.8 4.5 0.11 12.8 4.5 1.5 1 0 0 1 1 1 0 Ring finger domain PHD_4 PF16866.5 KFR02692.1 - 0.35 11.0 5.0 1.2 9.3 5.0 2.0 1 1 0 1 1 1 0 PHD-finger TP53IP5 PF15331.6 KFR02692.1 - 0.65 10.1 3.2 1.1 9.4 3.2 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 zf-RING_11 PF17123.5 KFR02692.1 - 0.69 9.7 4.6 1.4 8.8 4.6 1.5 1 0 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 KFR02692.1 - 1.8 8.8 5.1 1 9.6 2.7 1.8 2 0 0 2 2 2 0 FANCL C-terminal domain Macoilin PF09726.9 KFR02692.1 - 3.5 6.1 9.9 4.3 5.8 9.9 1.0 1 0 0 1 1 1 0 Macoilin family fn3 PF00041.21 KFR02693.1 - 1.6e-61 204.6 5.1 1.3e-11 44.7 0.1 5.6 5 0 0 5 5 5 5 Fibronectin type III domain I-set PF07679.16 KFR02693.1 - 2.5e-56 187.7 0.1 3.2e-15 56.0 0.0 5.7 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR02693.1 - 8.2e-56 186.6 3.5 6.8e-14 52.2 0.0 5.1 5 0 0 5 5 4 4 Immunoglobulin domain ig PF00047.25 KFR02693.1 - 2e-33 114.4 0.0 4.9e-07 29.8 0.0 4.6 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFR02693.1 - 1.6e-32 111.7 0.6 5.5e-08 33.0 0.0 5.3 5 0 0 5 5 5 4 Immunoglobulin domain V-set PF07686.17 KFR02693.1 - 2.8e-16 59.6 8.3 0.028 14.6 0.1 8.7 5 4 3 8 8 8 3 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 KFR02693.1 - 3.1e-13 50.1 8.0 0.0019 18.7 0.1 6.3 5 1 0 5 5 5 3 Purple acid Phosphatase, N-terminal domain C2-set_2 PF08205.12 KFR02693.1 - 1.7e-10 40.8 0.4 0.16 12.1 0.0 4.6 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain fn3_2 PF16893.5 KFR02693.1 - 1.4e-07 31.5 0.1 0.011 15.8 0.0 4.4 5 0 0 5 5 5 2 Fibronectin type III domain Ig_6 PF18452.1 KFR02693.1 - 4.2e-06 26.2 0.0 0.033 13.7 0.0 4.0 4 0 0 4 4 4 1 Immunoglobulin domain SusE PF14292.6 KFR02693.1 - 2.2e-05 24.6 0.2 0.7 10.2 0.0 4.7 4 0 0 4 4 4 1 SusE outer membrane protein Ig_4 PF16680.5 KFR02693.1 - 3.7e-05 23.9 0.0 0.65 10.3 0.0 4.2 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFR02693.1 - 0.00042 20.3 0.5 1.6 8.8 0.0 4.6 4 1 0 4 4 4 1 Izumo-like Immunoglobulin domain fn3_4 PF16794.5 KFR02693.1 - 0.0005 20.0 2.5 0.036 14.0 0.0 4.4 5 0 0 5 5 5 1 Fibronectin-III type domain C1-set PF07654.15 KFR02693.1 - 0.00069 19.9 0.9 0.13 12.6 0.0 4.6 6 0 0 6 6 5 1 Immunoglobulin C1-set domain DUF2369 PF10179.9 KFR02693.1 - 0.0057 17.0 0.0 30 5.1 0.0 5.0 5 0 0 5 5 5 0 Uncharacterised conserved protein (DUF2369) Syndecan PF01034.20 KFR02693.1 - 0.01 15.8 0.4 0.2 11.6 1.0 2.4 2 0 0 2 2 2 1 Syndecan domain Glycoprotein_G PF00802.19 KFR02693.1 - 0.031 13.6 0.5 0.06 12.7 0.5 1.4 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Adeno_E3_CR2 PF02439.15 KFR02693.1 - 0.062 13.1 4.7 0.14 11.9 4.7 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PRIMA1 PF16101.5 KFR02693.1 - 0.13 12.3 0.7 12 6.0 0.1 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 HECT PF00632.25 KFR02694.1 - 6.9e-101 337.8 0.1 1.1e-100 337.1 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KFR02694.1 - 1.6e-49 165.6 23.3 5.1e-13 48.9 0.7 5.1 4 0 0 4 4 4 4 WW domain C2 PF00168.30 KFR02694.1 - 2.2e-23 82.5 0.0 5e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain 2OG-FeII_Oxy_4 PF13661.6 KFR02694.1 - 0.085 13.5 0.0 0.21 12.3 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily RFX_DNA_binding PF02257.15 KFR02695.1 - 2e-27 95.6 0.0 7.1e-26 90.7 0.0 2.5 2 0 0 2 2 2 1 RFX DNA-binding domain Pox_D5 PF03288.16 KFR02695.1 - 0.00017 22.0 0.1 0.00046 20.6 0.1 1.7 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 KFR02695.1 - 0.015 15.2 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4111 PF13427.6 KFR02695.1 - 0.082 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) PRKG1_interact PF15898.5 KFR02696.1 - 0.02 15.8 19.8 0.02 15.8 19.8 3.8 2 2 1 3 3 3 0 cGMP-dependent protein kinase interacting domain ERM PF00769.19 KFR02696.1 - 0.55 10.0 42.5 0.042 13.7 35.0 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Macoilin PF09726.9 KFR02696.1 - 0.64 8.5 30.5 0.87 8.1 30.5 1.1 1 0 0 1 1 1 0 Macoilin family Rx_N PF18052.1 KFR02696.1 - 1.8 8.9 14.5 1.6 9.1 3.9 3.6 2 1 1 3 3 3 0 Rx N-terminal domain CheY-binding PF09078.11 KFR02696.1 - 4.5 7.5 6.4 3.1 8.0 0.4 2.8 2 0 0 2 2 2 0 CheY binding TPH PF13868.6 KFR02697.1 - 1.3e-85 287.1 152.3 1.3e-85 287.1 152.3 2.0 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain CA_like PF10563.9 KFR02697.1 - 0.12 12.3 0.1 0.29 11.0 0.1 1.7 1 0 0 1 1 1 0 Putative carbonic anhydrase Myosin_tail_1 PF01576.19 KFR02698.1 - 4.8e-52 177.0 182.1 4.5e-35 120.8 53.0 2.6 1 1 1 2 2 2 2 Myosin tail bZIP_1 PF00170.21 KFR02698.1 - 0.0014 18.6 3.9 0.0014 18.6 3.9 13.5 7 3 8 16 16 16 1 bZIP transcription factor CENP-Q PF13094.6 KFR02698.1 - 0.0044 17.2 11.3 0.0044 17.2 11.3 7.9 1 1 6 7 7 7 1 CENP-Q, a CENPA-CAD centromere complex subunit Filament PF00038.21 KFR02698.1 - 9.8 5.7 161.3 0.3 10.6 26.6 6.3 1 1 4 5 5 5 0 Intermediate filament protein SlyX PF04102.12 KFR02699.1 - 0.0013 19.3 3.2 0.0013 19.3 3.2 6.7 3 2 3 7 7 7 1 SlyX BLOC1_2 PF10046.9 KFR02699.1 - 0.0095 16.2 4.6 0.0095 16.2 4.6 4.7 1 1 2 4 4 4 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4349 PF14257.6 KFR02699.1 - 0.26 10.7 27.4 0.091 12.2 12.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) PUMA PF15826.5 KFR02699.1 - 2 8.6 4.7 0.46 10.6 0.5 2.0 2 0 0 2 2 2 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis DUF4407 PF14362.6 KFR02699.1 - 3.2 7.0 36.1 2.1 7.6 0.0 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) ATG16 PF08614.11 KFR02699.1 - 5.4 7.2 59.7 37 4.5 28.2 3.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Aldedh PF00171.22 KFR02700.1 - 5.9e-94 315.2 0.2 6.6e-94 315.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KFR02700.1 - 0.0019 17.7 0.1 1.4 8.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Spectrin PF00435.21 KFR02715.1 - 3.6e-70 233.1 28.2 4.9e-24 84.8 4.5 4.4 4 0 0 4 4 4 4 Spectrin repeat CH PF00307.31 KFR02715.1 - 1.2e-51 173.5 1.0 2e-25 89.1 0.0 3.2 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KFR02715.1 - 6.5e-28 96.6 0.0 2.5e-27 94.7 0.0 2.1 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_1 PF00036.32 KFR02715.1 - 9.9e-10 37.3 0.7 0.0012 18.2 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KFR02715.1 - 3.9e-07 30.4 0.2 2.4e-06 27.9 0.2 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KFR02715.1 - 9.2e-07 28.6 0.1 6.7e-06 25.9 0.2 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KFR02715.1 - 1.7e-06 27.5 1.0 0.0051 16.6 0.2 3.8 3 0 0 3 3 3 1 EF-hand domain CAMSAP_CH PF11971.8 KFR02715.1 - 2.2e-06 27.4 0.0 0.00012 21.9 0.0 2.7 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_11 PF08976.11 KFR02715.1 - 0.00068 20.5 0.1 0.003 18.4 0.1 2.1 1 0 0 1 1 1 1 EF-hand domain XisI PF08869.11 KFR02715.1 - 0.066 13.6 0.9 0.27 11.6 0.9 2.1 1 0 0 1 1 1 0 XisI protein DUF1690 PF07956.11 KFR02715.1 - 2.1 8.8 7.6 1.3 9.4 0.3 3.1 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) RRM_5 PF13893.6 KFR02716.1 - 9e-58 193.3 0.0 6.7e-50 167.9 0.1 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KFR02716.1 - 1.7e-18 66.2 0.1 5.3e-05 23.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KFR02716.1 - 1.9e-09 37.6 0.0 4.6e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 RRM-like domain RRM_occluded PF16842.5 KFR02716.1 - 6.1e-07 29.2 0.0 0.24 11.3 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif DUF4523 PF15023.6 KFR02716.1 - 8.1e-05 22.5 0.0 0.00019 21.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) RL PF17797.1 KFR02716.1 - 0.0015 18.4 0.0 3.5 7.6 0.0 2.8 3 0 0 3 3 3 2 RL domain Limkain-b1 PF11608.8 KFR02716.1 - 0.016 15.3 0.0 3 8.0 0.0 2.7 2 0 0 2 2 2 0 Limkain b1 RRM_3 PF08777.11 KFR02716.1 - 0.03 14.4 0.0 0.19 11.8 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif Ribosom_S12_S23 PF00164.25 KFR02717.1 - 3.6e-27 94.2 0.6 4.2e-27 94.0 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Syncollin PF15138.6 KFR02718.1 - 8.5e-41 138.7 0.6 9.4e-41 138.5 0.6 1.0 1 0 0 1 1 1 1 Syncollin Crystall_3 PF08964.10 KFR02718.1 - 0.061 13.5 0.0 0.069 13.3 0.0 1.1 1 0 0 1 1 1 0 Beta/Gamma crystallin Interferon PF00143.19 KFR02733.1 - 5.3e-35 121.0 0.1 6.1e-35 120.8 0.1 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain Interferon PF00143.19 KFR02734.1 - 2e-20 73.6 0.0 2.5e-20 73.3 0.0 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain UPF0542 PF15086.6 KFR02763.1 - 7e-18 64.3 1.8 7.5e-18 64.2 1.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0542 T_cell_tran_alt PF15128.6 KFR02763.1 - 0.062 13.1 0.7 0.07 12.9 0.7 1.0 1 0 0 1 1 1 0 T-cell leukemia translocation-altered Replic_Relax PF13814.6 KFR02775.1 - 0.055 13.5 0.2 2.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Replication-relaxation SAPS PF04499.15 KFR02782.1 - 1.4e-105 353.9 13.4 8.9e-67 225.9 7.7 3.7 3 2 1 4 4 4 2 SIT4 phosphatase-associated protein FliC PF12445.8 KFR02782.1 - 0.021 15.2 2.5 0.063 13.6 2.5 1.7 1 0 0 1 1 1 0 Flagellin protein Atx10homo_assoc PF09759.9 KFR02782.1 - 0.064 13.3 3.6 0.23 11.5 0.4 3.2 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Ldl_recept_b PF00058.17 KFR02784.1 - 8.1e-153 496.7 44.7 1.2e-13 51.3 0.0 20.5 20 0 0 20 20 20 20 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 KFR02784.1 - 2e-40 136.7 63.3 1.1e-12 48.0 8.1 5.4 5 0 0 5 5 5 4 Coagulation Factor Xa inhibitory site Ldl_recept_a PF00057.18 KFR02784.1 - 9e-32 109.0 49.9 4.5e-11 42.8 10.3 4.4 4 0 0 4 4 4 3 Low-density lipoprotein receptor domain class A DUF5050 PF16472.5 KFR02784.1 - 1.9e-22 79.8 0.0 6.2e-05 22.4 0.0 5.8 4 2 1 5 5 5 5 Domain of unknown function (DUF5050) SGL PF08450.12 KFR02784.1 - 2.6e-19 69.8 22.4 0.02 14.5 0.8 11.6 8 4 3 11 11 11 6 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KFR02784.1 - 1e-08 35.3 0.0 11 6.3 0.0 8.2 8 1 1 9 9 8 1 Arylesterase EGF PF00008.27 KFR02784.1 - 0.00031 21.0 64.3 0.0078 16.5 3.8 6.1 6 0 0 6 6 4 4 EGF-like domain NHL PF01436.21 KFR02784.1 - 0.038 14.0 0.0 15 5.8 0.0 4.9 5 0 0 5 5 5 0 NHL repeat Methyltransf_12 PF08242.12 KFR02784.1 - 0.046 14.5 0.4 2e+02 2.8 0.0 5.7 5 2 1 6 6 6 0 Methyltransferase domain cEGF PF12662.7 KFR02784.1 - 0.061 13.3 22.3 0.036 14.0 1.5 4.8 4 0 0 4 4 4 0 Complement Clr-like EGF-like Insulin_TMD PF17870.1 KFR02784.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Toxin_3 PF00537.18 KFR02785.1 - 0.011 15.9 0.7 0.019 15.2 0.7 1.4 1 0 0 1 1 1 0 Scorpion toxin-like domain Mucin PF01456.17 KFR02785.1 - 0.073 13.1 18.5 0.13 12.3 18.5 1.4 1 1 0 1 1 1 0 Mucin-like glycoprotein EccE PF11203.8 KFR02786.1 - 0.21 11.9 0.0 0.29 11.5 0.0 1.1 1 0 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE Choline_kinase PF01633.20 KFR02787.1 - 5.2e-77 258.2 0.1 7.6e-77 257.7 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KFR02787.1 - 9.8e-11 42.0 0.0 1.4e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFR02787.1 - 7.1e-07 28.8 0.2 2.4e-06 27.1 0.2 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase Helo_like_N PF17111.5 KFR02787.1 - 0.011 15.1 0.1 0.022 14.1 0.1 1.4 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Kdo PF06293.14 KFR02787.1 - 0.046 13.1 0.1 0.099 12.0 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFR02787.1 - 0.048 12.4 0.0 0.073 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase LRR_6 PF13516.6 KFR02788.1 - 5.4e-37 122.7 33.6 8.6e-05 22.3 0.0 11.8 12 0 0 12 12 12 8 Leucine Rich repeat LRR_RI_capping PF18779.1 KFR02788.1 - 6.8e-18 64.0 3.0 6.8e-18 64.0 3.0 2.7 2 0 0 2 2 2 1 Capping Ribonuclease inhibitor Leucine Rich Repeat LRR_4 PF12799.7 KFR02788.1 - 3.9e-15 55.7 32.9 0.0011 19.3 0.1 8.8 5 1 5 10 10 10 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFR02788.1 - 0.0015 18.3 24.5 6.4 6.6 1.2 7.6 5 1 3 8 8 8 5 Leucine rich repeat LRR_1 PF00560.33 KFR02788.1 - 0.0065 16.9 38.1 4.2 8.3 0.1 11.6 13 0 0 13 13 13 1 Leucine Rich Repeat Ras PF00071.22 KFR02789.1 - 9.6e-59 197.6 0.0 1.1e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR02789.1 - 8.6e-22 77.6 0.0 1.2e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR02789.1 - 1.1e-09 38.0 0.0 1.4e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFR02789.1 - 1.5e-06 27.9 0.2 8.6e-06 25.4 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFR02789.1 - 6.4e-06 26.2 0.0 0.046 13.6 0.0 2.5 2 1 1 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 KFR02789.1 - 1.6e-05 25.0 0.0 2.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFR02789.1 - 0.0037 16.8 0.0 0.032 13.8 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 KFR02789.1 - 0.017 14.5 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Septin PF00735.18 KFR02789.1 - 0.028 13.7 0.0 0.052 12.8 0.0 1.6 1 1 0 1 1 1 0 Septin G-alpha PF00503.20 KFR02789.1 - 0.028 13.6 0.0 1.3 8.1 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit ATP_bind_1 PF03029.17 KFR02789.1 - 0.032 14.0 0.5 0.72 9.6 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KFR02789.1 - 0.13 12.5 0.1 2.4 8.4 0.1 2.4 1 1 1 2 2 2 0 AAA domain Ldh_1_N PF00056.23 KFR02789.1 - 0.15 12.2 0.0 0.44 10.6 0.0 1.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain AAA_25 PF13481.6 KFR02789.1 - 0.16 11.5 0.0 0.39 10.3 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KFR02789.1 - 0.2 12.0 0.1 0.26 11.7 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain LRR_4 PF12799.7 KFR02790.1 - 2e-13 50.3 11.7 9.6e-06 25.9 0.1 3.9 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFR02790.1 - 3.9e-11 42.5 26.0 5.4e-06 26.1 2.4 3.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 KFR02790.1 - 8e-07 28.7 2.4 0.0001 21.9 0.5 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 KFR02790.1 - 0.0019 18.1 2.1 0.038 14.0 0.1 5.3 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 KFR02790.1 - 0.11 13.1 17.2 3 8.8 0.1 5.3 4 2 0 4 4 4 0 Leucine Rich Repeat COR PF16095.5 KFR02792.1 - 6e-05 22.9 0.1 0.00011 22.1 0.1 1.6 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain IRF-3 PF10401.9 KFR02793.1 - 8.8e-50 169.0 0.2 1.3e-49 168.4 0.2 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.17 KFR02793.1 - 1e-14 54.7 0.0 1.7e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor Gasdermin_C PF17708.1 KFR02793.1 - 0.043 13.9 0.0 0.088 12.9 0.0 1.5 1 0 0 1 1 1 0 Gasdermin PUB domain SHQ1 PF04925.15 KFR02793.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 SHQ1 protein Mito_carr PF00153.27 KFR02794.1 - 1.6e-64 213.9 1.6 5.5e-24 83.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein LRR_8 PF13855.6 KFR02795.1 - 6.2e-19 67.5 34.0 2.1e-09 37.0 7.9 5.3 4 1 1 5 5 5 3 Leucine rich repeat Peptidase_S68 PF10461.9 KFR02795.1 - 4.6e-18 65.1 14.8 7.3e-17 61.3 8.0 2.6 2 0 0 2 2 2 2 Peptidase S68 LRR_4 PF12799.7 KFR02795.1 - 2e-17 63.0 30.0 4.1e-06 27.1 2.6 6.6 4 2 3 7 7 7 5 Leucine Rich repeats (2 copies) ZU5 PF00791.20 KFR02795.1 - 2.1e-16 60.0 0.7 1e-13 51.5 0.0 2.5 2 0 0 2 2 2 2 ZU5 domain Death PF00531.22 KFR02795.1 - 7.2e-12 45.3 0.1 3.8e-11 43.0 0.2 2.2 2 0 0 2 2 2 1 Death domain LRR_1 PF00560.33 KFR02795.1 - 1.8 9.5 32.8 2.7 8.9 2.2 7.8 7 2 0 7 7 7 0 Leucine Rich Repeat Ribosomal_60s PF00428.19 KFR02796.1 - 5.5e-26 91.0 8.5 7.4e-26 90.6 8.5 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 KFR02796.1 - 0.015 15.6 0.6 0.017 15.5 0.0 1.4 2 0 0 2 2 2 0 EF-hand domain TFIID_30kDa PF03540.13 KFR02796.1 - 0.092 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit Patatin PF01734.22 KFR02797.1 - 1.3e-14 54.9 4.1 3.4e-13 50.2 4.1 2.4 1 1 0 1 1 1 1 Patatin-like phospholipase EF-hand_7 PF13499.6 KFR02798.1 - 1.1e-08 35.4 1.0 5e-06 26.9 0.1 3.6 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 KFR02798.1 - 9.8e-07 28.2 0.1 0.0099 15.7 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KFR02798.1 - 4.2e-06 25.9 0.6 0.032 13.8 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KFR02798.1 - 0.0046 16.8 0.0 0.02 14.7 0.0 2.2 1 1 0 1 1 1 1 EF-hand domain pair TMEM215 PF15746.5 KFR02798.1 - 0.43 10.0 2.4 0.46 9.9 1.3 1.6 1 1 0 1 1 1 0 TMEM215 family Peptidase_S46 PF10459.9 KFR02798.1 - 4.3 5.9 17.8 6.8 5.2 17.8 1.3 1 0 0 1 1 1 0 Peptidase S46 Ras PF00071.22 KFR02799.1 - 2.6e-51 173.5 0.2 2.8e-51 173.3 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR02799.1 - 1.7e-31 108.9 0.1 2.3e-31 108.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR02799.1 - 3.2e-15 56.0 0.0 3.6e-15 55.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFR02799.1 - 7.9e-09 35.2 0.0 8.9e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFR02799.1 - 1.5e-08 34.4 0.0 1e-07 31.7 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFR02799.1 - 1.6e-08 34.6 0.0 2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFR02799.1 - 6.6e-05 22.9 0.0 0.0054 16.7 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase CENP-M PF11111.8 KFR02799.1 - 0.01 15.0 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) SRPRB PF09439.10 KFR02799.1 - 0.013 14.9 0.0 0.016 14.7 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 KFR02799.1 - 0.013 15.5 0.0 2.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Dynamin family AAA_33 PF13671.6 KFR02799.1 - 0.038 14.1 0.0 0.051 13.7 0.0 1.3 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 KFR02799.1 - 0.051 12.9 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 KFR02799.1 - 0.074 12.8 0.1 0.36 10.5 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 KFR02799.1 - 0.083 12.4 0.0 0.17 11.3 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region Tetraspanin PF00335.20 KFR02800.1 - 9.7e-59 198.8 12.4 1.1e-58 198.7 12.4 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF4199 PF13858.6 KFR02800.1 - 0.00078 19.9 6.7 0.00078 19.9 6.7 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF4199) EI24 PF07264.11 KFR02800.1 - 0.032 14.5 4.8 0.097 12.9 5.0 1.6 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) MARVEL PF01284.23 KFR02800.1 - 0.11 12.6 10.2 0.12 12.4 1.0 2.4 1 1 1 2 2 2 0 Membrane-associating domain CD20 PF04103.15 KFR02800.1 - 0.18 11.9 10.5 0.042 13.9 6.7 1.9 1 1 0 1 1 1 0 CD20-like family DUF2569 PF10754.9 KFR02800.1 - 0.2 12.1 8.3 0.59 10.6 8.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) DUF599 PF04654.12 KFR02800.1 - 0.23 10.8 9.2 0.032 13.7 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF599 DUF4500 PF14937.6 KFR02800.1 - 0.27 11.3 3.1 15 5.7 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4500) TPR_21 PF09976.9 KFR02800.1 - 0.38 10.4 0.1 0.38 10.4 0.1 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain TMEM100 PF16311.5 KFR02800.1 - 2.5 7.7 5.5 3.3 7.3 4.3 1.9 1 1 1 2 2 2 0 Transmembrane protein 100 Baculo_11_kDa PF06143.11 KFR02800.1 - 5.5 6.6 14.0 18 5.0 2.0 3.3 2 1 1 3 3 3 0 Baculovirus 11 kDa family SUR7 PF06687.12 KFR02800.1 - 7.4 6.1 14.7 0.26 10.9 5.3 2.5 2 1 1 3 3 3 0 SUR7/PalI family DUF373 PF04123.13 KFR02800.1 - 7.9 5.8 10.6 17 4.7 8.9 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF373) Saf_2TM PF18303.1 KFR02800.1 - 8.6 5.9 7.2 4.4 6.9 1.9 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain RNA_pol_N PF01194.17 KFR02801.1 - 1.3e-33 115.0 0.2 1.5e-33 114.9 0.2 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Tetraspanin PF00335.20 KFR02802.1 - 2.3e-45 155.1 11.1 2.5e-45 155.0 11.1 1.0 1 0 0 1 1 1 1 Tetraspanin family CD20 PF04103.15 KFR02802.1 - 0.0002 21.5 5.6 0.00045 20.3 5.6 1.6 1 0 0 1 1 1 1 CD20-like family GP38 PF05268.11 KFR02802.1 - 0.046 13.4 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 DUF2207 PF09972.9 KFR02802.1 - 0.59 8.8 3.4 0.77 8.5 3.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MARVEL PF01284.23 KFR02802.1 - 4 7.5 12.4 0.85 9.6 8.5 1.8 2 0 0 2 2 2 0 Membrane-associating domain Glyco_hydro_18 PF00704.28 KFR02803.1 - 2.7e-20 73.4 0.0 3.2e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Adaptin_N PF01602.20 KFR02804.1 - 5.3e-146 487.2 4.3 6.9e-146 486.9 4.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KFR02804.1 - 2.4e-45 153.4 0.0 6.3e-45 152.0 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KFR02804.1 - 3.8e-17 62.6 1.2 8.2e-16 58.3 1.2 2.4 1 1 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KFR02804.1 - 4.2e-09 36.6 0.4 9.6e-07 29.0 0.0 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFR02804.1 - 1e-05 25.8 3.9 0.0091 16.4 0.1 4.7 3 1 2 5 5 5 1 HEAT repeats RIX1 PF08167.12 KFR02804.1 - 0.00095 19.0 2.9 0.11 12.3 0.2 3.6 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis TIP120 PF08623.10 KFR02804.1 - 0.021 14.6 1.5 3.9 7.2 0.1 2.5 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) IFRD PF05004.13 KFR02804.1 - 1.3 8.0 5.0 0.54 9.3 0.6 2.5 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) VWD PF00094.25 KFR02805.1 - 1.5e-78 262.6 16.4 4.5e-29 101.7 0.6 3.8 4 0 0 4 4 4 3 von Willebrand factor type D domain C8 PF08742.11 KFR02805.1 - 6.8e-38 128.9 38.9 2.9e-17 62.9 12.6 5.9 5 1 1 6 6 6 3 C8 domain TIL PF01826.17 KFR02805.1 - 7e-18 64.6 56.4 6.3e-11 42.3 18.2 9.6 9 2 1 10 10 10 3 Trypsin Inhibitor like cysteine rich domain VWC PF00093.18 KFR02805.1 - 3.9e-06 27.1 20.5 1.3e-05 25.4 4.4 9.6 7 4 1 8 8 8 2 von Willebrand factor type C domain VWD PF00094.25 KFR02806.1 - 1.2e-27 97.1 0.4 1.8e-27 96.5 0.4 1.2 1 0 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.11 KFR02806.1 - 3.1e-16 59.5 9.8 7.3e-16 58.4 9.8 1.7 1 0 0 1 1 1 1 C8 domain VWD PF00094.25 KFR02807.1 - 4.9e-31 108.1 1.7 4.9e-31 108.1 1.7 1.7 2 0 0 2 2 2 1 von Willebrand factor type D domain C8 PF08742.11 KFR02807.1 - 8.1e-18 64.6 15.0 8.1e-18 64.6 15.0 2.7 3 1 0 3 3 3 1 C8 domain Pacifastin_I PF05375.13 KFR02807.1 - 9.1e-06 25.3 9.3 9.1e-06 25.3 9.3 4.2 3 2 0 3 3 3 1 Pacifastin inhibitor (LCMII) TIL PF01826.17 KFR02807.1 - 0.011 15.9 6.0 0.011 15.9 6.0 4.8 4 1 0 4 4 4 0 Trypsin Inhibitor like cysteine rich domain LRR_8 PF13855.6 KFR02811.1 - 9.9e-42 140.5 20.4 9.2e-14 51.0 2.9 5.3 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KFR02811.1 - 5.7e-23 80.6 14.6 1.4e-06 28.6 0.0 5.9 4 1 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFR02811.1 - 7.9e-20 71.1 0.0 1.9e-12 47.2 0.0 2.5 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) I-set PF07679.16 KFR02811.1 - 3.2e-08 33.5 0.0 5.6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_9 PF14580.6 KFR02811.1 - 3.7e-08 33.1 4.4 0.0015 18.1 0.1 3.2 1 1 2 3 3 3 3 Leucine-rich repeat Ig_3 PF13927.6 KFR02811.1 - 1.3e-07 32.1 0.0 3.4e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.33 KFR02811.1 - 1.1e-06 28.3 19.3 0.69 10.7 0.0 8.4 9 0 0 9 9 8 2 Leucine Rich Repeat V-set PF07686.17 KFR02811.1 - 0.00029 21.0 0.4 0.0033 17.6 0.4 2.2 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_6 PF18452.1 KFR02811.1 - 0.00031 20.2 0.4 0.00066 19.2 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 KFR02811.1 - 0.00089 19.4 0.0 0.002 18.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFR02811.1 - 0.00097 19.4 0.0 0.0022 18.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain LRRNT PF01462.18 KFR02811.1 - 0.0025 17.4 4.5 0.0025 17.4 4.5 2.2 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 KFR02811.1 - 0.004 17.1 21.2 4 7.7 0.1 8.2 9 0 0 9 9 9 1 Leucine Rich repeat Insulin_TMD PF17870.1 KFR02811.1 - 0.058 13.5 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DAG1 PF05454.11 KFR02811.1 - 0.072 12.5 0.3 0.11 11.9 0.3 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) PAX PF00292.18 KFR02812.1 - 1.2e-51 173.8 0.2 2e-51 173.1 0.2 1.3 1 0 0 1 1 1 1 'Paired box' domain Homeodomain PF00046.29 KFR02812.1 - 6.3e-21 74.0 2.2 1.7e-20 72.6 2.2 1.8 1 0 0 1 1 1 1 Homeodomain HTH_32 PF13565.6 KFR02812.1 - 0.00032 21.3 2.2 0.0059 17.2 0.0 3.1 3 1 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KFR02812.1 - 0.002 18.2 0.5 0.037 14.1 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain Homeobox_KN PF05920.11 KFR02812.1 - 0.0032 17.3 0.1 0.0095 15.8 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.6 KFR02812.1 - 0.0092 15.8 0.4 0.073 12.9 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain Arf PF00025.21 KFR02813.1 - 7e-66 221.0 0.2 7.8e-66 220.8 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFR02813.1 - 7.3e-11 42.3 0.1 9.5e-11 42.0 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFR02813.1 - 1.4e-09 37.8 0.1 1.4e-09 37.7 0.1 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KFR02813.1 - 1.6e-09 37.5 0.0 2.7e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.12 KFR02813.1 - 2.3e-09 36.9 0.0 2.6e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFR02813.1 - 7.1e-09 35.3 0.0 8.6e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFR02813.1 - 0.013 15.6 0.1 0.017 15.2 0.1 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase GRIP PF01465.20 KFR02814.1 - 3.1e-17 62.2 0.3 5.6e-16 58.2 0.0 2.7 2 0 0 2 2 2 1 GRIP domain SPA PF08616.10 KFR02815.1 - 1e-14 54.4 0.1 2.8e-14 53.0 0.0 1.7 2 0 0 2 2 2 1 Stabilization of polarity axis DENN PF02141.21 KFR02815.1 - 1.7e-07 31.3 8.3 1.9e-07 31.2 4.4 2.5 2 1 0 2 2 2 1 DENN (AEX-3) domain Avl9 PF09794.9 KFR02815.1 - 0.0019 17.0 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 Transport protein Avl9 RAM PF15320.6 KFR02815.1 - 0.29 11.7 1.7 0.56 10.8 0.1 2.2 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein SAPS PF04499.15 KFR02816.1 - 4.3e-76 256.7 23.6 2.2e-60 204.9 3.4 4.0 4 0 0 4 4 4 2 SIT4 phosphatase-associated protein Arm PF00514.23 KFR02816.1 - 0.005 16.8 0.9 2.3 8.4 0.0 3.5 3 1 1 4 4 4 2 Armadillo/beta-catenin-like repeat CDC45 PF02724.14 KFR02816.1 - 9.3 4.4 12.6 18 3.5 12.6 1.3 1 0 0 1 1 1 0 CDC45-like protein SBF2 PF12335.8 KFR02817.1 - 5.3e-109 363.2 4.5 9e-109 362.5 4.5 1.4 1 0 0 1 1 1 1 Myotubularin protein Myotub-related PF06602.14 KFR02817.1 - 9.9e-90 301.0 0.0 1.7e-89 300.2 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DENN PF02141.21 KFR02817.1 - 7.9e-53 179.2 0.1 1.7e-52 178.1 0.1 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain GRAM PF02893.20 KFR02817.1 - 2.6e-21 75.6 0.0 3.6e-20 71.9 0.0 2.5 2 0 0 2 2 2 1 GRAM domain uDENN PF03456.18 KFR02817.1 - 1.9e-18 66.9 1.2 1.9e-18 66.9 1.2 2.1 2 0 0 2 2 1 1 uDENN domain PH PF00169.29 KFR02817.1 - 1.2e-13 51.5 0.1 3.8e-13 49.8 0.1 1.9 1 0 0 1 1 1 1 PH domain dDENN PF03455.19 KFR02817.1 - 1.3e-07 31.5 0.0 5.8e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 dDENN domain SPA PF08616.10 KFR02817.1 - 7.1e-05 22.7 0.0 0.0002 21.3 0.0 1.8 1 0 0 1 1 1 1 Stabilization of polarity axis PH_11 PF15413.6 KFR02817.1 - 0.0068 16.8 0.4 0.041 14.3 0.4 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.10 KFR02817.1 - 0.058 13.7 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 Plant pleckstrin homology-like region PH_9 PF15410.6 KFR02817.1 - 0.086 13.2 0.4 2.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain IpaB_EvcA PF03278.13 KFR02817.1 - 0.11 12.2 0.2 0.28 10.9 0.2 1.6 1 0 0 1 1 1 0 IpaB/EvcA family RVT_1 PF00078.27 KFR02840.1 - 0.092 12.2 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4211 PF13926.6 KFR02841.1 - 5.6e-28 97.8 0.6 5.6e-28 97.8 0.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) DUF4196 PF13846.6 KFR02841.1 - 2.4e-14 53.5 4.6 2.4e-14 53.5 4.6 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4196) Myotub-related PF06602.14 KFR02844.1 - 1.4e-153 511.0 0.0 1.8e-153 510.6 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 KFR02844.1 - 7.6e-19 67.7 0.0 1.6e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Y_phosphatase PF00102.27 KFR02844.1 - 0.00027 20.6 0.0 0.00053 19.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase 3-PAP PF12578.8 KFR02844.1 - 0.00093 18.9 0.2 0.0022 17.7 0.2 1.7 1 0 0 1 1 1 1 Myotubularin-associated protein DSPc PF00782.20 KFR02844.1 - 0.0043 16.9 0.0 0.0093 15.8 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFR02844.1 - 0.031 14.2 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family NYD-SP28_assoc PF14775.6 KFR02844.1 - 0.041 14.0 5.4 0.84 9.8 0.9 3.3 3 0 0 3 3 3 0 Sperm tail C-terminal domain Cep57_CLD PF14073.6 KFR02845.1 - 9.1e-68 227.8 37.8 9.1e-68 227.8 37.8 2.4 2 0 0 2 2 2 1 Centrosome localisation domain of Cep57 Cep57_MT_bd PF06657.13 KFR02845.1 - 2.8e-21 75.8 3.5 2.8e-21 75.8 3.5 4.2 3 1 1 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Tsi6 PF18660.1 KFR02845.1 - 0.73 9.9 4.9 0.35 10.9 0.3 2.9 2 1 0 2 2 2 0 Tsi6 DUF1515 PF07439.11 KFR02845.1 - 8.7 6.4 7.5 8.3 6.5 1.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) FAM76 PF16046.5 KFR02846.1 - 2.2e-91 306.3 33.8 2.6e-91 306.1 33.8 1.0 1 0 0 1 1 1 1 FAM76 protein Macoilin PF09726.9 KFR02846.1 - 0.086 11.4 25.2 0.11 11.0 25.2 1.1 1 0 0 1 1 1 0 Macoilin family OmpH PF03938.14 KFR02846.1 - 0.3 11.4 11.6 0.68 10.3 11.6 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MPS2 PF17060.5 KFR02846.1 - 0.66 9.2 13.5 0.88 8.8 11.7 2.0 1 1 0 1 1 1 0 Monopolar spindle protein 2 Kinesin_assoc PF16183.5 KFR02846.1 - 0.67 10.1 6.1 0.32 11.1 1.3 2.1 2 0 0 2 2 2 0 Kinesin-associated Metal_resist PF13801.6 KFR02846.1 - 1.7 8.8 7.1 12 6.1 2.2 2.3 2 0 0 2 2 2 0 Heavy-metal resistance DUF3552 PF12072.8 KFR02846.1 - 2.5 7.5 23.1 0.02 14.3 13.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) NicO PF03824.16 KFR02846.1 - 2.6 7.3 7.4 4.5 6.5 7.4 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein DUF2614 PF11023.8 KFR02846.1 - 3.1 7.9 8.4 1.1 9.3 1.1 2.3 1 1 1 2 2 2 0 Zinc-ribbon containing domain bZIP_2 PF07716.15 KFR02846.1 - 5.1 7.2 10.1 2.8 8.1 4.2 2.6 2 0 0 2 2 2 0 Basic region leucine zipper PA26 PF04636.13 KFR02847.1 - 3.6e-204 678.7 0.6 4.1e-204 678.5 0.6 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) CMD PF02627.20 KFR02847.1 - 0.002 18.2 0.0 0.006 16.6 0.0 1.9 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Cwf_Cwc_15 PF04889.12 KFR02848.1 - 2.2e-76 256.9 22.0 2.9e-76 256.5 22.0 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein UPF0524 PF15823.5 KFR02848.1 - 0.46 9.8 2.5 0.35 10.2 0.8 1.6 1 1 1 2 2 2 0 UPF0524 of C3orf70 Angiomotin_C PF12240.8 KFR02849.1 - 7.2e-91 303.3 40.8 3.6e-90 301.0 18.7 3.5 2 1 1 3 3 3 2 Angiomotin C terminal DUF1216 PF06746.11 KFR02849.1 - 0.41 10.6 3.9 1.4 8.9 3.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) NPV_P10 PF05531.12 KFR02849.1 - 0.59 10.6 3.4 1.2 9.7 1.4 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2043 PF09740.9 KFR02849.1 - 1.2 9.8 3.3 1.1 10.0 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2043) PilO PF04350.13 KFR02849.1 - 3.5 7.8 11.5 5.6 7.1 0.7 2.8 2 0 0 2 2 2 0 Pilus assembly protein, PilO Ank_4 PF13637.6 KFR02850.1 - 8.5e-33 112.3 4.7 2.3e-15 56.7 0.1 4.1 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFR02850.1 - 2.2e-31 108.3 5.7 4.7e-18 65.6 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFR02850.1 - 1.5e-24 85.3 3.5 3.4e-09 36.8 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KFR02850.1 - 1.1e-23 80.7 1.4 1e-06 28.6 0.0 4.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KFR02850.1 - 1.8e-21 75.9 5.2 4.6e-10 39.6 0.1 3.3 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Sulfotransfer_4 PF17784.1 KFR02850.1 - 0.041 13.7 0.8 0.064 13.1 0.8 1.3 1 0 0 1 1 1 0 Sulfotransferase domain Mre11_DNA_bind PF04152.14 KFR02851.1 - 7.1e-49 166.4 0.4 7.1e-49 166.4 0.4 2.2 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KFR02851.1 - 1.4e-15 58.3 1.5 2.6e-15 57.5 1.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFR02851.1 - 2.7e-05 24.4 0.0 0.00032 20.9 0.0 2.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain 7tm_1 PF00001.21 KFR02852.1 - 2.4e-49 168.1 24.4 3e-49 167.7 24.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR02852.1 - 1.6e-16 60.5 23.2 2e-16 60.2 23.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFR02852.1 - 7.5e-05 22.6 16.9 0.0001 22.2 16.9 1.2 1 0 0 1 1 1 1 Olfactory receptor DUF2116 PF09889.9 KFR02852.1 - 0.075 13.0 0.2 0.31 11.1 0.2 2.1 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Innexin PF00876.18 KFR02853.1 - 4.6e-17 62.3 3.6 4.6e-17 62.3 3.6 1.6 1 1 1 2 2 2 1 Innexin DUF2207 PF09972.9 KFR02853.1 - 0.64 8.7 5.5 5 5.8 2.0 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Cu-oxidase_3 PF07732.15 KFR02854.1 - 2.5e-31 108.2 0.3 1.3e-10 41.3 0.0 5.0 5 0 0 5 5 5 3 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFR02854.1 - 4.2e-23 81.6 10.5 1e-11 44.7 3.6 6.0 5 1 0 5 5 5 4 Multicopper oxidase L6_membrane PF05805.12 KFR02855.1 - 1.8e-65 220.1 16.4 2.2e-65 219.8 16.4 1.1 1 0 0 1 1 1 1 L6 membrane protein SSF PF00474.17 KFR02856.1 - 4.2e-26 91.8 19.2 6.1e-26 91.2 19.2 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family V-set PF07686.17 KFR02857.1 - 2e-05 24.7 0.1 3.1e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Receptor_2B4 PF11465.8 KFR02857.1 - 0.00026 21.2 0.1 0.0004 20.6 0.1 1.3 1 0 0 1 1 1 1 Natural killer cell receptor 2B4 I-set PF07679.16 KFR02857.1 - 0.018 15.1 0.3 0.053 13.6 0.3 1.8 1 1 0 1 1 1 0 Immunoglobulin I-set domain ig PF00047.25 KFR02857.1 - 0.039 14.1 1.5 0.04 14.1 0.3 1.6 2 0 0 2 2 2 0 Immunoglobulin domain Herpes_gE PF02480.16 KFR02857.1 - 0.046 12.5 0.0 0.048 12.4 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Med17 PF10156.9 KFR02858.1 - 2e-08 33.4 0.4 3e-08 32.8 0.4 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Thioredoxin_12 PF18400.1 KFR02858.1 - 0.039 13.8 0.8 0.076 12.9 0.1 1.8 2 0 0 2 2 2 0 Thioredoxin-like domain DUF1907 PF08925.11 KFR02859.1 - 6.5e-125 416.2 0.0 7.3e-125 416.1 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) TAF1D PF15333.6 KFR02860.1 - 1.4e-66 224.4 18.5 4.3e-66 222.8 18.5 1.8 1 1 0 1 1 1 1 TATA box-binding protein-associated factor 1D ALMS_motif PF15309.6 KFR02861.1 - 6.5e-27 94.7 21.0 1.1e-26 93.9 21.0 1.3 1 0 0 1 1 1 1 ALMS motif FlxA PF14282.6 KFR02861.1 - 0.011 15.7 1.7 0.011 15.7 1.7 2.8 4 0 0 4 4 4 0 FlxA-like protein Stimulus_sens_1 PF13756.6 KFR02861.1 - 0.23 12.0 3.1 9.1 6.9 0.4 2.3 2 0 0 2 2 2 0 Stimulus-sensing domain AAA_9 PF12781.7 KFR02861.1 - 0.43 9.7 6.1 0.57 9.3 0.2 2.2 2 0 0 2 2 2 0 ATP-binding dynein motor region DUF45 PF01863.17 KFR02861.1 - 1.8 8.5 11.9 15 5.6 11.9 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF45 DNA_pol_B PF00136.21 KFR02863.1 - 0.76 8.4 4.1 0.85 8.3 4.1 1.0 1 0 0 1 1 1 0 DNA polymerase family B FAM199X PF15814.5 KFR02863.1 - 2.9 6.9 5.4 2.8 6.9 5.4 1.0 1 0 0 1 1 1 0 Protein family FAM199X FliP PF00813.20 KFR02864.1 - 0.081 12.8 0.4 0.11 12.4 0.4 1.1 1 0 0 1 1 1 0 FliP family DUF2259 PF10016.9 KFR02864.1 - 0.089 12.7 0.5 0.11 12.4 0.5 1.2 1 0 0 1 1 1 0 Predicted secreted protein (DUF2259) ISG65-75 PF11727.8 KFR02865.1 - 0.18 11.0 6.5 0.19 10.9 6.5 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein FUSC-like PF12805.7 KFR02865.1 - 0.21 10.6 6.2 0.25 10.4 6.2 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS vATP-synt_E PF01991.18 KFR02865.1 - 0.46 9.9 12.3 0.51 9.7 12.3 1.0 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit HSCB_C PF07743.13 KFR02865.1 - 0.48 10.9 13.0 1.9 9.0 13.0 2.2 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain DUF4519 PF15012.6 KFR02866.1 - 6.8e-29 99.8 4.5 7.5e-29 99.7 4.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4519) DUF4448 PF14610.6 KFR02866.1 - 0.00044 20.1 0.1 0.00047 20.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Orf78 PF06024.12 KFR02866.1 - 0.00078 19.7 0.0 0.00081 19.7 0.0 1.0 1 0 0 1 1 1 1 Orf78 (ac78) DUF2232 PF09991.9 KFR02866.1 - 0.0024 17.1 0.0 0.0027 16.9 0.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2232) FTCD_C PF04961.12 KFR02866.1 - 0.0036 17.1 0.1 0.0038 17.0 0.1 1.0 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase CrgA PF06781.12 KFR02866.1 - 0.0092 16.0 0.2 0.01 15.9 0.2 1.0 1 0 0 1 1 1 1 Cell division protein CrgA DUF2208 PF09973.9 KFR02866.1 - 0.016 14.9 0.0 0.016 14.9 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Vma12 PF11712.8 KFR02866.1 - 0.031 14.3 0.0 0.034 14.2 0.0 1.1 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF5305 PF17231.2 KFR02866.1 - 0.039 13.4 0.1 0.041 13.3 0.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5305) TMEM154 PF15102.6 KFR02866.1 - 0.048 13.6 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family EMC3_TMCO1 PF01956.16 KFR02866.1 - 0.051 13.3 0.1 0.057 13.1 0.1 1.0 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF3671 PF12420.8 KFR02866.1 - 0.051 13.6 0.0 0.056 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF3899 PF13038.6 KFR02866.1 - 0.062 13.8 0.0 0.063 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) DUF515 PF04415.12 KFR02866.1 - 0.063 11.7 0.2 0.064 11.6 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DotU PF09850.9 KFR02866.1 - 0.065 13.0 0.1 0.069 12.9 0.1 1.0 1 0 0 1 1 1 0 Type VI secretion system protein DotU DUF2116 PF09889.9 KFR02866.1 - 0.13 12.3 0.2 0.19 11.7 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) CEP63 PF17045.5 KFR02867.1 - 1.2e-61 209.0 43.1 1.2e-61 209.0 43.1 4.2 3 2 0 3 3 3 1 Centrosomal protein of 63 kDa Tup_N PF08581.10 KFR02867.1 - 0.002 18.4 6.2 0.002 18.4 6.2 8.0 5 4 2 8 8 8 3 Tup N-terminal CdiI_N PF18228.1 KFR02867.1 - 0.018 14.9 1.6 0.045 13.6 0.2 2.5 2 0 0 2 2 2 0 CdiI N-terminal domain Aa_trans PF01490.18 KFR02868.1 - 1.7e-54 185.1 27.3 5.1e-39 134.1 9.7 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein 7tm_1 PF00001.21 KFR02869.1 - 2.4e-43 148.4 25.3 2.9e-43 148.1 25.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFR02869.1 - 8.3e-09 35.5 26.1 2.4e-08 34.0 26.0 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4233 PF14017.6 KFR02869.1 - 9.7 6.6 18.8 6.6 7.1 1.2 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4233) Cadherin PF00028.17 KFR02870.1 - 0 1178.0 69.0 1.4e-22 80.0 0.0 25.9 27 0 0 27 27 26 25 Cadherin domain Laminin_G_2 PF02210.24 KFR02870.1 - 6.1e-24 85.0 1.7 4.7e-23 82.1 0.1 3.3 4 0 0 4 4 3 1 Laminin G domain Cadherin_2 PF08266.12 KFR02870.1 - 9.9e-19 67.0 0.8 1.1 9.1 0.0 13.0 15 0 0 15 15 15 3 Cadherin-like RET_CLD1 PF17756.1 KFR02870.1 - 3.4e-18 66.1 0.7 0.0045 17.3 0.0 11.4 13 0 0 13 13 13 2 RET Cadherin like domain 1 Laminin_G_1 PF00054.23 KFR02870.1 - 7.2e-18 65.1 0.0 4.6e-17 62.5 0.0 2.5 2 0 0 2 2 2 1 Laminin G domain Cadherin_3 PF16184.5 KFR02870.1 - 1.9e-17 63.3 55.1 0.037 14.0 0.4 17.6 19 0 0 19 19 19 8 Cadherin-like EGF PF00008.27 KFR02870.1 - 9.7e-12 45.0 59.0 0.00012 22.3 10.8 4.7 4 0 0 4 4 4 3 EGF-like domain EGF_CA PF07645.15 KFR02870.1 - 6e-05 23.2 11.0 6e-05 23.2 11.0 4.4 3 1 1 4 4 3 1 Calcium-binding EGF domain RMI1_C PF16099.5 KFR02870.1 - 0.0004 20.2 1.0 13 5.6 0.0 5.4 6 0 0 6 6 6 0 Recq-mediated genome instability protein 1, C-terminal OB-fold hEGF PF12661.7 KFR02870.1 - 0.0015 19.1 53.2 0.0082 16.8 8.1 4.9 4 0 0 4 4 4 2 Human growth factor-like EGF Cadherin_4 PF17803.1 KFR02870.1 - 0.082 13.5 99.4 0.086 13.5 0.7 15.8 18 0 0 18 18 15 0 Bacterial cadherin-like domain Big_9 PF17963.1 KFR02870.1 - 0.086 13.6 0.1 0.086 13.6 0.1 17.3 19 0 0 19 19 18 0 Bacterial Ig domain MLANA PF14991.6 KFR02870.1 - 0.5 10.6 1.5 0.93 9.8 0.0 2.2 2 0 0 2 2 1 0 Protein melan-A DUF777 PF05606.11 KFR02870.1 - 9.4 6.0 7.1 0.82 9.4 0.1 2.9 4 0 0 4 4 4 0 Borrelia burgdorferi protein of unknown function (DUF777) CHORD PF04968.12 KFR02872.1 - 2e-46 156.5 20.0 2e-26 92.5 8.3 2.9 3 0 0 3 3 3 2 CHORD CS PF04969.16 KFR02872.1 - 1.3e-13 51.8 0.1 2.7e-13 50.8 0.1 1.6 1 0 0 1 1 1 1 CS domain TFR_dimer PF04253.15 KFR02873.1 - 1.4e-36 125.2 0.0 2.9e-36 124.2 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KFR02873.1 - 5e-20 72.0 0.0 1.4e-18 67.3 0.0 2.3 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 KFR02873.1 - 1.4e-11 44.3 0.0 3.6e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 PA domain RPA PF10134.9 KFR02873.1 - 0.1 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Replication initiator protein A TPR_17 PF13431.6 KFR02873.1 - 0.18 12.3 0.3 2.5 8.7 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat GETHR PF05671.11 KFR02874.1 - 0.0031 16.8 1.9 0.0031 16.8 1.9 1.8 1 1 0 1 1 1 1 GETHR pentapeptide repeat (5 copies) TFR_dimer PF04253.15 KFR02876.1 - 8e-37 126.0 0.1 1.7e-36 124.9 0.1 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KFR02876.1 - 1.4e-18 67.3 0.0 6.1e-18 65.2 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 KFR02876.1 - 2.7e-14 52.9 0.0 5.9e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 PA domain PPR_3 PF13812.6 KFR02876.1 - 0.0092 16.0 0.0 0.03 14.4 0.0 1.8 1 0 0 1 1 1 1 Pentatricopeptide repeat domain Ferric_reduct PF01794.19 KFR02877.1 - 1.4e-23 83.4 6.0 1.4e-23 83.4 6.0 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KFR02877.1 - 4.6e-22 78.8 0.0 1.6e-20 73.8 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFR02877.1 - 9e-16 57.9 0.0 2e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ni_hydr_CYTB PF01292.20 KFR02877.1 - 0.055 13.1 3.8 2.7 7.5 0.5 2.4 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 NAD_binding_1 PF00175.21 KFR02877.1 - 0.079 13.6 0.0 0.33 11.6 0.0 2.2 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain ORMDL PF04061.14 KFR02877.1 - 5.2 6.9 9.2 1.9 8.3 2.8 2.6 2 0 0 2 2 2 0 ORMDL family Tyrosinase PF00264.20 KFR02878.1 - 6.1e-41 141.1 1.8 9.9e-41 140.4 1.8 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Laminin_EGF PF00053.24 KFR02878.1 - 0.2 11.8 11.3 0.09 12.9 6.7 2.5 2 1 0 2 2 2 0 Laminin EGF domain ANF_receptor PF01094.28 KFR02879.1 - 1.6e-17 63.6 0.0 2.4e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 KFR02880.1 - 9.3e-58 195.8 24.8 1.3e-57 195.2 24.8 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 KFR02880.1 - 7.4e-46 156.9 0.0 1e-45 156.4 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region GluR_Homer-bdg PF10606.9 KFR02880.1 - 1.6e-20 73.0 12.1 5.3e-20 71.4 12.1 2.0 1 0 0 1 1 1 1 Homer-binding domain of metabotropic glutamate receptor NCD3G PF07562.14 KFR02880.1 - 8.2e-16 57.7 13.1 1.6e-15 56.8 13.1 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR DUF5438 PF17506.2 KFR02880.1 - 0.086 13.2 0.5 0.29 11.5 0.5 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5438) Ras PF00071.22 KFR02881.1 - 5.3e-42 143.2 0.0 6.2e-42 142.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR02881.1 - 6.7e-29 100.5 0.0 9.3e-29 100.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR02881.1 - 4.6e-10 39.2 0.0 5.7e-10 38.9 0.0 1.2 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFR02881.1 - 1.1e-06 28.2 0.0 1.2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TniB PF05621.11 KFR02881.1 - 0.0029 17.0 0.0 0.0096 15.3 0.0 1.8 1 1 1 2 2 2 1 Bacterial TniB protein MMR_HSR1 PF01926.23 KFR02881.1 - 0.0048 17.0 0.0 0.0071 16.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 KFR02881.1 - 0.012 15.1 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KFR02881.1 - 0.018 15.3 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KFR02881.1 - 0.039 13.7 0.0 0.66 9.7 0.0 2.3 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 KFR02881.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TMEM135_C_rich PF15982.5 KFR02883.1 - 1.9e-24 86.8 1.5 4.4e-24 85.6 0.2 2.3 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 Tim17 PF02466.19 KFR02883.1 - 4.6e-08 33.4 0.1 1e-07 32.3 0.1 1.7 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4010 PF13194.6 KFR02883.1 - 0.1 12.2 0.6 0.26 11.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) Frizzled PF01534.17 KFR02885.1 - 4.1e-126 420.4 23.7 1.2e-125 418.9 23.7 1.7 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 KFR02885.1 - 1.2e-13 51.6 1.3 2.3e-13 50.7 1.3 1.5 1 0 0 1 1 1 1 Fz domain DUF5083 PF16890.5 KFR02885.1 - 0.0052 16.5 0.5 0.0099 15.6 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5083) DUF3852 PF12963.7 KFR02885.1 - 5.6 7.4 9.3 0.69 10.3 2.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3852) DUF4462 PF14692.6 KFR02886.1 - 0.19 11.2 0.9 0.61 9.6 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) Trypsin PF00089.26 KFR02887.1 - 9.1e-11 42.0 0.1 5e-10 39.6 0.1 2.2 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFR02887.1 - 5.8e-08 33.8 0.0 1e-07 32.9 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain FB_lectin PF07367.11 KFR02887.1 - 0.16 11.9 0.3 2.2 8.2 0.0 2.1 2 0 0 2 2 2 0 Fungal fruit body lectin Malic_M PF03949.15 KFR02888.1 - 1.2e-103 345.9 0.4 1.5e-103 345.5 0.4 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KFR02888.1 - 3.3e-81 271.4 0.0 5e-81 270.9 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Peptidase_S28 PF05577.12 KFR02889.1 - 1.4e-101 340.4 0.0 1.7e-101 340.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.7 KFR02889.1 - 9.9e-05 23.0 0.2 0.00089 19.9 0.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFR02889.1 - 0.00087 18.6 0.0 0.0014 17.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S37 PF05576.11 KFR02889.1 - 0.0019 17.0 0.0 0.0039 15.9 0.0 1.5 1 0 0 1 1 1 1 PS-10 peptidase S37 Peptidase_S9 PF00326.21 KFR02889.1 - 0.0019 17.7 0.0 0.0041 16.6 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KFR02889.1 - 0.0072 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2920 PF11144.8 KFR02889.1 - 0.017 14.3 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Rep_fac-A_C PF08646.10 KFR02890.1 - 9.6e-11 41.6 0.4 1.7e-10 40.9 0.4 1.3 1 0 0 1 1 1 1 Replication factor-A C terminal domain Ribosomal_L40e PF01020.17 KFR02890.1 - 6.4 6.8 6.8 2.1 8.3 3.0 2.0 2 0 0 2 2 2 0 Ribosomal L40e family Ras PF00071.22 KFR02892.1 - 2.6e-58 196.2 0.0 3.2e-58 195.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR02892.1 - 1.4e-37 128.5 0.0 2.7e-37 127.6 0.0 1.4 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR02892.1 - 3.7e-15 55.8 0.0 4.8e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFR02892.1 - 4.3e-09 36.1 0.0 5.2e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFR02892.1 - 8.2e-06 25.9 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFR02892.1 - 1.4e-05 25.1 0.3 0.042 13.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 KFR02892.1 - 1.5e-05 24.9 0.7 0.003 17.4 0.1 2.3 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KFR02892.1 - 1.9e-05 24.3 0.0 0.00019 21.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 KFR02892.1 - 0.0003 21.2 0.0 0.0016 18.8 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 KFR02892.1 - 0.00087 18.8 0.3 0.0049 16.4 0.3 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 KFR02892.1 - 0.00088 18.8 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 KFR02892.1 - 0.0034 17.4 0.1 0.0087 16.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 KFR02892.1 - 0.0038 17.0 0.2 0.022 14.5 0.2 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 KFR02892.1 - 0.0055 16.7 0.4 0.092 12.8 0.0 2.4 2 1 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 KFR02892.1 - 0.008 16.6 0.1 0.015 15.7 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KFR02892.1 - 0.0095 16.1 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KFR02892.1 - 0.01 15.8 0.1 0.023 14.6 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 KFR02892.1 - 0.012 15.9 0.2 0.035 14.4 0.1 1.9 2 1 0 2 2 2 0 AAA domain TIR_2 PF13676.6 KFR02892.1 - 0.038 14.6 0.1 0.048 14.3 0.1 1.2 1 0 0 1 1 1 0 TIR domain ABC_tran PF00005.27 KFR02892.1 - 0.078 13.5 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter cobW PF02492.19 KFR02892.1 - 0.083 12.5 0.3 13 5.4 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.21 KFR02892.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KFR02892.1 - 0.1 12.3 0.1 0.13 11.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFR02892.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KFR02892.1 - 0.19 11.6 0.4 0.47 10.3 0.3 1.8 1 1 1 2 2 2 0 NTPase CTD_bind PF04818.13 KFR02893.1 - 1.3e-06 29.1 0.0 4.4e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. SHOCT PF09851.9 KFR02893.1 - 0.0024 17.5 0.9 0.013 15.2 0.2 2.5 2 0 0 2 2 2 1 Short C-terminal domain CFIA_Pcf11 PF11526.8 KFR02893.1 - 0.0038 17.7 0.1 0.0038 17.7 0.1 5.9 4 2 0 4 4 4 1 Subunit of cleavage factor IA Pcf11 DNA_pol3_a_NI PF14480.6 KFR02893.1 - 0.081 12.9 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus I EF-hand_14 PF17959.1 KFR02893.1 - 0.39 11.1 7.7 7.4 7.0 0.8 3.7 3 1 0 3 3 3 0 EF-hand domain Ank_4 PF13637.6 KFR02894.1 - 1.5e-38 130.7 13.3 2.5e-08 34.3 0.2 7.1 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFR02894.1 - 5.9e-35 119.7 6.3 1.1e-07 32.3 0.2 4.8 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KFR02894.1 - 4.4e-25 87.0 13.8 3.2e-06 27.4 0.2 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KFR02894.1 - 1.5e-24 85.7 10.6 2.3e-08 34.1 0.0 6.1 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFR02894.1 - 8e-22 75.0 9.7 0.0019 18.5 0.0 7.8 8 0 0 8 8 8 6 Ankyrin repeat Cob_adeno_trans PF01923.18 KFR02894.1 - 0.022 14.9 1.3 0.045 13.9 1.3 1.5 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Tmemb_cc2 PF10267.9 KFR02894.1 - 0.062 12.4 6.7 0.086 12.0 6.7 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF2400 PF09674.10 KFR02894.1 - 0.074 13.0 0.5 11 5.9 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) Vps51 PF08700.11 KFR02894.1 - 0.096 12.8 2.8 0.27 11.3 2.8 1.8 1 0 0 1 1 1 0 Vps51/Vps67 HAUS6_N PF14661.6 KFR02894.1 - 3.2 7.3 6.5 5.4 6.5 6.5 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF1640 PF07798.11 KFR02895.1 - 4.7e-60 202.6 15.8 7.2e-60 202.0 15.8 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) Vac_Fusion PF02346.16 KFR02895.1 - 0.066 12.8 3.7 0.17 11.6 0.1 3.2 2 2 1 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 HALZ PF02183.18 KFR02895.1 - 0.27 11.5 2.6 0.3 11.4 1.0 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF2408 PF10303.9 KFR02895.1 - 0.47 11.0 8.1 1.7 9.2 7.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) IZUMO PF15005.6 KFR02895.1 - 0.97 9.9 7.0 1.6 9.3 6.3 1.7 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated YabA PF06156.13 KFR02895.1 - 3.5 8.3 11.5 0.85 10.3 4.2 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Fungal_TACC PF12709.7 KFR02895.1 - 5.6 7.5 8.4 4.3 7.8 1.4 3.0 3 1 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins PDZ PF00595.24 KFR02896.1 - 1.4e-66 220.9 8.4 8.9e-22 77.2 0.1 3.4 3 0 0 3 3 3 3 PDZ domain Guanylate_kin PF00625.21 KFR02896.1 - 2e-65 219.9 0.1 3.2e-65 219.2 0.1 1.3 1 0 0 1 1 1 1 Guanylate kinase PDZ_6 PF17820.1 KFR02896.1 - 2.5e-30 104.1 4.3 2.9e-11 43.0 0.2 3.7 3 0 0 3 3 3 3 PDZ domain PDZ_assoc PF10600.9 KFR02896.1 - 2.9e-27 95.3 5.5 6.1e-27 94.3 5.5 1.6 1 0 0 1 1 1 1 PDZ-associated domain of NMDA receptors PDZ_2 PF13180.6 KFR02896.1 - 3.6e-17 62.5 2.5 0.00013 22.2 0.0 3.7 4 0 0 4 4 4 3 PDZ domain MAGUK_N_PEST PF10608.9 KFR02896.1 - 1.8e-13 51.0 0.6 3.6e-13 50.0 0.6 1.6 1 0 0 1 1 1 1 Polyubiquitination (PEST) N-terminal domain of MAGUK SH3_2 PF07653.17 KFR02896.1 - 8.2e-09 35.0 0.0 2.7e-08 33.4 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFR02896.1 - 9.6e-09 34.7 0.0 2.4e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFR02896.1 - 0.0021 17.9 0.6 0.011 15.6 0.0 2.6 3 0 0 3 3 3 1 Variant SH3 domain LsmAD PF06741.13 KFR02897.1 - 0.0061 17.1 2.4 0.0066 17.0 2.4 1.0 1 0 0 1 1 1 1 LsmAD domain L27_1 PF09058.10 KFR02897.1 - 0.054 13.5 0.3 0.054 13.5 0.3 1.9 2 1 0 2 2 2 0 L27_1 TMEM126 PF07114.11 KFR02898.1 - 1.5e-75 252.6 0.8 1.8e-75 252.3 0.8 1.0 1 0 0 1 1 1 1 Transmembrane protein 126 DUF4618 PF15397.6 KFR02899.1 - 0.0008 18.9 18.6 0.00097 18.6 18.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) Csm1_N PF18504.1 KFR02899.1 - 0.0013 19.0 17.6 0.018 15.3 3.0 3.7 2 1 0 3 3 3 2 Csm1 N-terminal domain PRKG1_interact PF15898.5 KFR02899.1 - 0.0053 17.6 18.0 0.18 12.8 7.9 2.3 1 1 1 2 2 2 2 cGMP-dependent protein kinase interacting domain SMBP PF16785.5 KFR02899.1 - 0.022 15.0 0.9 0.033 14.4 0.9 1.4 1 0 0 1 1 1 0 Small metal-binding protein AcylCoA_dehyd_C PF12186.8 KFR02899.1 - 0.048 13.8 1.1 0.048 13.8 1.1 2.2 2 1 0 3 3 3 0 Acyl-CoA dehydrogenase C terminal DUF5344 PF17279.2 KFR02899.1 - 0.072 13.7 0.7 0.072 13.7 0.7 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5344) SOGA PF11365.8 KFR02899.1 - 0.36 12.0 17.6 4.3 8.5 11.5 2.8 1 1 1 2 2 2 0 Protein SOGA Gp-FAR-1 PF05823.12 KFR02899.1 - 0.37 11.1 9.5 0.8 10.0 6.6 2.5 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF4446 PF14584.6 KFR02899.1 - 0.6 10.1 12.6 0.67 9.9 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) UPF0231 PF06062.11 KFR02899.1 - 0.69 10.2 9.6 3 8.1 2.2 2.5 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0231) DUF2031 PF09592.10 KFR02899.1 - 1.1 8.7 16.9 0.45 10.0 14.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2031) ThiD2 PF17792.1 KFR02899.1 - 1.4 9.4 8.3 1.7 9.1 4.5 2.1 1 1 1 2 2 2 0 ThiD2 family DUF241 PF03087.14 KFR02899.1 - 1.9 8.3 14.6 5.9 6.7 14.6 1.8 1 1 0 1 1 1 0 Arabidopsis protein of unknown function TPR_MLP1_2 PF07926.12 KFR02899.1 - 2 8.5 21.4 0.62 10.1 13.4 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein YabA PF06156.13 KFR02899.1 - 2.3 8.9 15.6 6.4 7.5 4.6 3.1 1 1 2 3 3 3 0 Initiation control protein YabA DUF1319 PF07028.11 KFR02899.1 - 3.3 8.0 11.4 3.9 7.7 4.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) LPP PF04728.13 KFR02899.1 - 3.6 8.0 8.4 2 8.9 0.4 3.4 4 0 0 4 4 3 0 Lipoprotein leucine-zipper RNase_J_C PF17770.1 KFR02899.1 - 6.9 7.8 6.9 6.3 7.9 0.1 3.1 1 1 1 2 2 2 0 Ribonuclease J C-terminal domain DUF883 PF05957.13 KFR02899.1 - 8.4 7.1 8.2 2 9.1 0.8 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) ANTH PF07651.16 KFR02900.1 - 9.8e-83 277.3 0.8 1.4e-82 276.9 0.8 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KFR02900.1 - 9.7e-14 51.5 0.1 2e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 ENTH domain WD40 PF00400.32 KFR02901.1 - 4.4e-11 43.1 9.7 1e-05 26.1 0.0 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR02901.1 - 0.0019 18.5 0.3 8.1 6.8 0.0 4.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFR02901.1 - 0.0021 16.8 0.0 0.0081 14.8 0.0 1.9 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Lipoprotein_3 PF00938.17 KFR02901.1 - 0.16 12.2 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 Lipoprotein DUF775 PF05603.12 KFR02903.1 - 3.2e-42 144.3 0.4 4.7e-42 143.8 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Ten_N PF06484.12 KFR02909.1 - 1e-31 111.2 6.9 1.1e-31 111.0 6.9 1.0 1 0 0 1 1 1 1 Teneurin Intracellular Region DUF1203 PF06718.11 KFR02909.1 - 0.056 13.7 0.1 0.069 13.4 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1203) CysA_C_terminal PF17850.1 KFR02912.1 - 0.12 12.9 5.2 1.2e+02 3.4 5.2 3.5 1 1 0 1 1 1 0 CysA C-terminal regulatory domain DicB PF05358.11 KFR02922.1 - 0.76 10.0 2.7 1.1 9.4 0.1 2.5 3 0 0 3 3 3 0 DicB protein AAA PF00004.29 KFR02923.1 - 1.1e-57 194.2 0.0 1.7e-41 141.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.18 KFR02923.1 - 9.2e-13 48.2 0.0 2.6e-11 43.5 0.0 2.7 3 0 0 3 3 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_lid_3 PF17862.1 KFR02923.1 - 6.9e-11 41.8 0.4 1.5e-10 40.7 0.4 1.6 1 0 0 1 1 1 1 AAA+ lid domain CDC48_2 PF02933.17 KFR02923.1 - 2.5e-10 40.0 1.1 2.3e-09 36.9 0.1 2.7 3 0 0 3 3 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 KFR02923.1 - 1.3e-09 38.5 0.2 0.014 15.7 0.0 4.3 2 2 2 4 4 4 2 AAA domain AAA_16 PF13191.6 KFR02923.1 - 2.6e-08 34.5 0.0 0.0035 17.8 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 KFR02923.1 - 4.2e-08 33.1 0.0 0.01 15.6 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KFR02923.1 - 4.4e-08 33.5 0.0 0.013 15.9 0.0 3.5 4 0 0 4 4 2 2 RNA helicase AAA_2 PF07724.14 KFR02923.1 - 5.8e-08 33.0 0.0 7.6e-06 26.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KFR02923.1 - 6.5e-07 29.5 0.0 0.025 14.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KFR02923.1 - 7.2e-07 29.3 0.0 0.001 19.0 0.1 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KFR02923.1 - 2.1e-06 28.3 0.0 0.017 15.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 KFR02923.1 - 2.4e-06 27.0 0.0 0.046 12.9 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 KFR02923.1 - 2.5e-06 27.7 0.0 0.092 12.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KFR02923.1 - 1.1e-05 24.9 0.1 0.0043 16.4 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KFR02923.1 - 3.1e-05 23.8 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 KFR02923.1 - 3.7e-05 23.7 0.0 0.058 13.4 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 KFR02923.1 - 5e-05 23.3 0.1 0.29 11.0 0.0 4.0 2 2 1 4 4 4 1 ATPase domain predominantly from Archaea NACHT PF05729.12 KFR02923.1 - 8.4e-05 22.5 0.0 0.73 9.7 0.0 3.7 3 1 0 3 3 3 2 NACHT domain AAA_17 PF13207.6 KFR02923.1 - 0.00041 20.8 0.0 1.5 9.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain ATPase PF06745.13 KFR02923.1 - 0.0011 18.4 0.1 0.02 14.3 0.0 2.8 2 1 1 3 3 3 1 KaiC AAA_3 PF07726.11 KFR02923.1 - 0.0026 17.6 0.0 0.38 10.6 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KFR02923.1 - 0.0026 18.0 0.0 0.29 11.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KFR02923.1 - 0.0028 17.0 0.0 1.3 8.2 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin ABC_tran PF00005.27 KFR02923.1 - 0.0032 18.0 0.0 0.017 15.7 0.0 2.2 2 0 0 2 2 1 1 ABC transporter Sigma54_activat PF00158.26 KFR02923.1 - 0.0041 16.8 0.0 1.6 8.4 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 KFR02923.1 - 0.0044 16.6 0.0 0.099 12.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region KTI12 PF08433.10 KFR02923.1 - 0.0047 16.4 1.0 3.9 6.8 0.0 3.5 4 0 0 4 4 4 1 Chromatin associated protein KTI12 IstB_IS21 PF01695.17 KFR02923.1 - 0.0083 15.9 0.0 0.29 10.9 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.6 KFR02923.1 - 0.0083 15.7 0.2 2 7.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 KFR02923.1 - 0.0089 15.2 0.0 1 8.5 0.1 2.5 2 0 0 2 2 2 1 NB-ARC domain Parvo_NS1 PF01057.17 KFR02923.1 - 0.013 14.6 0.0 2.2 7.3 0.0 2.8 4 0 0 4 4 3 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 KFR02923.1 - 0.014 15.2 0.2 1.2 8.8 0.1 2.6 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 KFR02923.1 - 0.015 15.2 0.1 0.2 11.5 0.0 2.7 3 1 0 3 3 3 0 Rad17 P-loop domain AAA_19 PF13245.6 KFR02923.1 - 0.035 14.5 0.2 4 7.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 KFR02923.1 - 0.086 12.7 0.0 16 5.3 0.0 2.9 2 1 0 2 2 2 0 NTPase CPT PF07931.12 KFR02923.1 - 0.086 12.7 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein wnt PF00110.19 KFR02924.1 - 5.6e-125 417.0 15.7 6.3e-125 416.8 15.7 1.0 1 0 0 1 1 1 1 wnt family V-SNARE_C PF12352.8 KFR02925.1 - 1.3e-17 63.9 4.6 1.6e-17 63.5 1.4 2.4 1 1 1 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KFR02925.1 - 2.1e-05 24.3 0.1 5.2e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 Sec20 V-SNARE PF05008.15 KFR02925.1 - 0.00073 19.9 1.9 0.0015 18.9 1.9 1.6 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus EzrA PF06160.12 KFR02925.1 - 0.011 13.9 4.8 0.014 13.6 4.8 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF2344 PF10105.9 KFR02925.1 - 0.035 13.9 0.2 0.049 13.5 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) EF-G-binding_N PF07299.11 KFR02925.1 - 0.037 14.6 2.2 0.066 13.7 0.6 2.1 1 1 1 2 2 2 0 Elongation factor G-binding protein, N-terminal HSCB_C PF07743.13 KFR02925.1 - 0.052 14.0 0.9 0.43 11.1 0.4 2.5 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain DUF1690 PF07956.11 KFR02925.1 - 0.31 11.4 5.2 0.64 10.4 5.2 1.5 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) GIT_CC PF16559.5 KFR02925.1 - 0.48 10.3 3.2 2.8 7.9 0.0 2.8 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor FlxA PF14282.6 KFR02925.1 - 1.2 9.1 5.1 1.4 8.9 0.2 2.2 1 1 1 2 2 2 0 FlxA-like protein zf-U11-48K PF05253.12 KFR02926.1 - 1.4e-21 75.9 11.3 4.6e-10 39.2 0.1 2.3 2 0 0 2 2 2 2 U11-48K-like CHHC zinc finger Keratin PF02422.16 KFR02927.1 - 4.8e-31 106.3 12.5 5.1e-31 106.2 12.5 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFR02928.1 - 4.8e-31 106.3 12.5 5.1e-31 106.2 12.5 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFR02929.1 - 2e-21 75.5 9.4 2.1e-21 75.4 9.4 1.0 1 0 0 1 1 1 1 Keratin Ndr PF03096.14 KFR02934.1 - 7.3e-87 290.7 0.1 8.4e-87 290.5 0.1 1.0 1 0 0 1 1 1 1 Ndr family DUF4462 PF14692.6 KFR02935.1 - 0.22 11.0 0.3 0.61 9.6 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) DUF4201 PF13870.6 KFR02936.1 - 7.7e-37 126.7 24.8 7.7e-37 126.7 24.8 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) DUF948 PF06103.11 KFR02936.1 - 0.088 13.1 0.4 0.088 13.1 0.4 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) NFRKB_winged PF14465.6 KFR02936.1 - 0.22 11.7 3.5 7.2 6.9 0.3 3.0 2 0 0 2 2 2 0 NFRKB Winged Helix-like ADK PF00406.22 KFR02936.1 - 4.5 7.4 9.8 0.55 10.3 4.0 2.3 2 1 1 3 3 3 0 Adenylate kinase Pkinase PF00069.25 KFR02937.1 - 9.2e-71 238.3 0.9 1.1e-70 238.0 0.9 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR02937.1 - 1.1e-20 74.1 0.2 2e-20 73.2 0.1 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFR02937.1 - 8.2e-10 39.0 0.0 1.8e-06 28.0 0.0 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFR02937.1 - 0.00086 18.2 0.1 0.0074 15.1 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KFR02937.1 - 0.0059 16.0 0.5 0.01 15.2 0.5 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFR02937.1 - 0.0068 16.0 0.2 0.016 14.8 0.2 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase PAS_3 PF08447.12 KFR02937.1 - 0.084 13.2 0.1 0.26 11.6 0.1 1.8 1 0 0 1 1 1 0 PAS fold ABC1 PF03109.16 KFR02937.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 ABC1 family DUF667 PF05018.13 KFR02938.1 - 1.1e-79 266.5 0.8 1.2e-79 266.3 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Peptidase_M10 PF00413.24 KFR02939.1 - 5.2e-59 198.6 0.0 7.6e-59 198.1 0.0 1.2 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 KFR02939.1 - 1.6e-44 149.6 22.7 2e-15 56.4 1.3 5.3 4 1 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 KFR02939.1 - 4.8e-07 29.9 0.1 1.1e-06 28.8 0.1 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Reprolysin_3 PF13582.6 KFR02939.1 - 0.0032 18.0 0.1 0.0059 17.1 0.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 KFR02939.1 - 0.016 14.8 0.6 1.3 8.6 0.1 2.2 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) DUF4953 PF16313.5 KFR02939.1 - 0.028 13.6 0.1 0.041 13.1 0.1 1.2 1 0 0 1 1 1 0 Met-zincin Metallopep PF12044.8 KFR02939.1 - 0.045 12.3 0.0 0.07 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_5 PF13688.6 KFR02939.1 - 0.055 13.6 0.1 0.084 13.0 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M54 PF07998.11 KFR02939.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 Peptidase_M66 PF10462.9 KFR02939.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 HVSL PF09749.9 KFR02940.1 - 1.6e-48 165.2 0.0 1.8e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein zf-C2H2 PF00096.26 KFR02941.1 - 2.3e-58 191.5 147.4 2.6e-06 27.5 0.9 17.2 17 0 0 17 17 17 15 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFR02941.1 - 1.1e-54 180.5 139.0 4.1e-11 42.8 1.4 17.5 18 0 0 18 18 18 13 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR02941.1 - 2.1e-39 130.8 133.3 0.0013 19.4 2.1 17.1 17 0 0 17 17 17 15 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFR02941.1 - 2.9e-25 87.9 85.2 0.0011 19.1 0.1 15.0 15 0 0 15 15 15 10 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFR02941.1 - 3.9e-16 58.8 94.4 0.016 15.6 0.6 14.9 15 0 0 15 15 14 9 Zinc-finger of C2H2 type BolA PF01722.18 KFR02941.1 - 2.8e-06 27.5 36.8 0.34 11.2 0.2 8.8 3 2 5 10 10 10 4 BolA-like protein zf-C2H2_6 PF13912.6 KFR02941.1 - 5.1e-05 23.2 1.6 5.1e-05 23.2 1.6 17.1 17 1 0 17 17 17 8 C2H2-type zinc finger MRP-S23 PF10484.9 KFR02941.1 - 0.014 15.7 0.1 75 3.6 0.0 5.0 3 2 1 5 5 5 0 Mitochondrial ribosomal protein S23 Antimicrobial_3 PF08025.11 KFR02941.1 - 0.18 11.8 1.0 39 4.3 0.1 4.0 3 0 0 3 3 3 0 Spider antimicrobial peptide zf_PR_Knuckle PF18445.1 KFR02941.1 - 0.98 9.3 23.7 8.1 6.4 0.3 8.0 8 0 0 8 8 7 0 PR zinc knuckle motif UPF0728 PF15092.6 KFR02941.1 - 2 8.3 8.6 3.8 7.4 0.1 4.7 4 1 0 4 4 4 0 Uncharacterised protein family UPF0728 Ta0938 PF11494.8 KFR02941.1 - 5.6 7.3 21.3 14 6.0 2.6 7.0 2 2 7 9 9 9 0 Ta0938 zf-Di19 PF05605.12 KFR02941.1 - 7.8 6.9 105.8 0.42 10.9 9.9 11.3 5 3 9 14 14 14 0 Drought induced 19 protein (Di19), zinc-binding cNMP_binding PF00027.29 KFR02942.1 - 3.2e-17 62.4 0.0 5.8e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Kinesin PF00225.23 KFR02943.1 - 5.8e-107 357.5 0.0 5.8e-107 357.5 0.0 2.1 2 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KFR02943.1 - 4.5e-47 159.7 0.1 1.9e-46 157.7 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding CENP-F_leu_zip PF10473.9 KFR02943.1 - 0.66 10.0 67.8 0.049 13.7 27.4 4.7 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_22 PF13401.6 KFR02943.1 - 6.2 7.1 0.0 6.2 7.1 0.0 3.7 3 1 1 4 4 4 0 AAA domain Zona_pellucida PF00100.23 KFR02944.1 - 1.2e-50 172.7 0.7 1.5e-50 172.4 0.7 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain EGF PF00008.27 KFR02944.1 - 2.9e-06 27.4 5.1 2.9e-06 27.4 5.1 2.0 2 0 0 2 2 2 1 EGF-like domain hEGF PF12661.7 KFR02944.1 - 0.0017 18.9 2.1 0.0017 18.9 2.1 2.3 3 0 0 3 3 3 1 Human growth factor-like EGF EGF_2 PF07974.13 KFR02944.1 - 0.0032 17.8 5.6 0.0032 17.8 5.6 1.9 2 0 0 2 2 2 1 EGF-like domain cEGF PF12662.7 KFR02944.1 - 0.037 14.0 1.1 0.11 12.4 1.1 1.8 1 0 0 1 1 1 0 Complement Clr-like EGF-like EGF_3 PF12947.7 KFR02944.1 - 0.25 11.6 5.3 0.55 10.5 5.3 1.6 1 0 0 1 1 1 0 EGF domain PLL PF18587.1 KFR02945.1 - 1.3e-50 171.0 0.3 3.1e-50 169.8 0.3 1.6 1 0 0 1 1 1 1 PTX/LNS-Like (PLL) domain 7tm_2 PF00002.24 KFR02945.1 - 2.3e-29 102.4 19.0 3.3e-29 101.9 19.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 KFR02945.1 - 7.9e-14 51.9 5.1 7.9e-14 51.9 5.1 2.1 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif End3 PF12761.7 KFR02945.1 - 0.018 15.2 1.4 4.8 7.3 0.2 2.2 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 7tm_2 PF00002.24 KFR02946.1 - 5.7e-27 94.6 19.6 7.3e-27 94.2 19.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 KFR02946.1 - 8.7e-16 58.2 3.8 2.2e-15 56.9 3.8 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Myosin_tail_1 PF01576.19 KFR02947.1 - 7.4e-15 53.9 60.3 7.6e-15 53.9 42.9 2.1 1 1 1 2 2 2 2 Myosin tail Spc7 PF08317.11 KFR02947.1 - 0.00092 18.2 59.7 0.005 15.8 23.4 3.2 1 1 2 3 3 3 3 Spc7 kinetochore protein PRKG1_interact PF15898.5 KFR02947.1 - 0.0013 19.6 13.5 0.0013 19.6 13.5 4.7 2 2 2 4 4 4 1 cGMP-dependent protein kinase interacting domain THOC7 PF05615.13 KFR02947.1 - 0.0029 17.9 16.4 0.0029 17.9 16.4 4.2 1 1 2 3 3 2 1 Tho complex subunit 7 Taxilin PF09728.9 KFR02947.1 - 0.0045 16.2 58.6 0.51 9.5 46.3 2.5 1 1 1 2 2 2 2 Myosin-like coiled-coil protein Filament PF00038.21 KFR02947.1 - 0.015 14.9 54.7 0.65 9.5 37.4 2.8 1 1 0 1 1 1 0 Intermediate filament protein NPV_P10 PF05531.12 KFR02947.1 - 0.043 14.3 20.5 0.1 13.1 1.2 4.8 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein APG6_N PF17675.1 KFR02947.1 - 0.069 13.7 69.8 0.079 13.5 26.4 4.0 1 1 1 3 3 3 0 Apg6 coiled-coil region ADIP PF11559.8 KFR02947.1 - 0.086 12.9 53.8 0.41 10.7 11.8 4.0 1 1 4 5 5 5 0 Afadin- and alpha -actinin-Binding EzrA PF06160.12 KFR02947.1 - 0.089 11.0 42.5 0.15 10.2 5.5 3.4 1 1 1 3 3 3 0 Septation ring formation regulator, EzrA Leu_zip PF15294.6 KFR02947.1 - 0.21 11.1 47.1 0.062 12.8 28.8 2.4 1 1 1 2 2 2 0 Leucine zipper CRISPR_Cas2 PF09827.9 KFR02947.1 - 0.31 11.2 3.4 0.33 11.2 0.3 2.7 2 1 0 2 2 2 0 CRISPR associated protein Cas2 Cep57_MT_bd PF06657.13 KFR02947.1 - 0.73 10.3 43.2 0.23 11.9 0.6 5.5 1 1 4 5 5 5 0 Centrosome microtubule-binding domain of Cep57 BRE1 PF08647.11 KFR02947.1 - 1.6 8.9 51.3 0.29 11.2 6.8 4.3 1 1 3 4 4 4 0 BRE1 E3 ubiquitin ligase Fib_alpha PF08702.10 KFR02947.1 - 1.9 8.7 32.6 0.57 10.4 5.5 3.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 KFR02947.1 - 2 8.8 57.4 1.3 9.4 25.8 3.3 1 1 2 3 3 3 0 Fez1 FlaC_arch PF05377.11 KFR02947.1 - 3.1 8.3 31.2 5.9 7.4 0.6 5.7 5 1 0 5 5 5 0 Flagella accessory protein C (FlaC) Peptidase_S46 PF10459.9 KFR02947.1 - 3.8 6.0 26.5 4.9 5.7 26.5 1.1 1 0 0 1 1 1 0 Peptidase S46 ATG16 PF08614.11 KFR02947.1 - 4.1 7.6 60.4 2.4 8.3 19.6 3.9 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.6 KFR02947.1 - 4.2 5.9 42.1 0.096 11.3 16.7 2.2 1 1 1 2 2 2 0 AAA domain DUF3450 PF11932.8 KFR02947.1 - 4.5 6.5 45.6 0.29 10.4 15.0 3.8 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF4407 PF14362.6 KFR02947.1 - 6.6 6.0 37.5 1.8e+04 -6.3 37.4 2.6 1 1 0 1 1 0 0 Domain of unknown function (DUF4407) HOOK PF05622.12 KFR02947.1 - 7.7 4.5 60.4 87 1.0 60.4 2.1 1 1 0 1 1 1 0 HOOK protein DUF3584 PF12128.8 KFR02947.1 - 8.7 3.7 50.9 11 3.3 49.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Laminin_II PF06009.12 KFR02947.1 - 9.8 6.2 29.8 0.31 11.0 5.9 4.0 1 1 3 4 4 4 0 Laminin Domain II IRS PF02174.17 KFR02948.1 - 2.2e-30 104.5 0.0 3.8e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.29 KFR02948.1 - 6.1e-06 26.7 0.1 1.1e-05 25.9 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFR02948.1 - 0.035 14.5 1.4 1 9.8 1.4 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain Cytochrome_cB PF11783.8 KFR02948.1 - 0.13 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c bacterial RNA_pol_A_bac PF01000.26 KFR02949.1 - 2.6e-40 137.3 0.0 3.6e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KFR02949.1 - 4e-12 45.4 0.0 5.6e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain COQ9 PF08511.11 KFR02950.1 - 1.8e-35 120.5 1.0 2.8e-35 119.9 0.5 1.6 2 0 0 2 2 2 1 COQ9 CIAPIN1 PF05093.13 KFR02951.1 - 4.8e-22 78.3 18.2 3.8e-17 62.6 3.5 2.7 2 1 1 3 3 3 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Methyltransf_11 PF08241.12 KFR02951.1 - 4.4e-06 27.3 0.0 8.9e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFR02951.1 - 0.00014 21.7 0.1 0.0003 20.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFR02951.1 - 0.0002 21.2 0.0 0.00029 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFR02951.1 - 0.00054 20.6 0.0 0.0011 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFR02951.1 - 0.0011 19.6 0.0 0.0021 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KFR02951.1 - 0.091 12.0 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain GFO_IDH_MocA PF01408.22 KFR02952.1 - 4.6e-14 53.3 0.0 1.7e-13 51.5 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 KFR02952.1 - 0.0015 19.0 0.0 0.0047 17.5 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Enkurin PF13864.6 KFR02953.1 - 1.6e-26 92.6 1.9 1.6e-26 92.6 1.9 2.8 3 0 0 3 3 3 1 Calmodulin-binding DUF2262 PF10020.9 KFR02953.1 - 0.08 13.3 0.1 0.08 13.3 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2262) PB1 PF00564.24 KFR02954.1 - 5.3e-13 48.7 0.3 1.1e-12 47.6 0.0 1.6 2 0 0 2 2 2 1 PB1 domain PDZ PF00595.24 KFR02954.1 - 2.1e-11 44.0 0.3 4.4e-11 43.0 0.2 1.6 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFR02954.1 - 1.2e-07 31.4 0.1 3.4e-07 30.0 0.1 1.7 2 0 0 2 2 2 1 PDZ domain ubiquitin PF00240.23 KFR02955.1 - 0.0043 16.8 0.2 0.007 16.1 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin family Pex14_N PF04695.13 KFR02955.1 - 2.4 8.8 7.0 0.27 11.9 2.3 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LBP_BPI_CETP PF01273.25 KFR02956.1 - 3.5e-27 95.0 0.6 1.1e-26 93.4 0.1 2.0 2 1 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP_C PF02886.17 KFR02956.1 - 5.8e-27 94.7 1.5 6.7e-27 94.5 0.5 1.7 2 0 0 2 2 2 1 LBP / BPI / CETP family, C-terminal domain Copine PF07002.16 KFR02957.1 - 2.9e-88 295.0 0.0 4.5e-88 294.3 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.30 KFR02957.1 - 2e-26 92.3 0.0 8.3e-13 48.5 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 KFR02957.1 - 9.8e-06 25.8 0.0 2.1e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus Nefa_Nip30_N PF10187.9 KFR02958.1 - 6.7e-32 110.0 22.9 1.3e-31 109.1 22.9 1.5 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 SPRY PF00622.28 KFR02959.1 - 5.9e-21 74.8 0.5 1e-20 74.0 0.5 1.4 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.6 KFR02959.1 - 1.4e-08 34.4 14.4 1.4e-08 34.4 14.4 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFR02959.1 - 0.00012 21.8 10.6 0.00012 21.8 10.6 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 ARL2_Bind_BART PF11527.8 KFR02960.1 - 1.4e-33 115.4 8.6 1.7e-33 115.2 8.6 1.1 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART SF3A3 PF16837.5 KFR02960.1 - 0.5 10.9 4.4 2.5 8.7 0.1 2.9 2 2 1 3 3 3 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 MARVEL PF01284.23 KFR02961.1 - 1.8e-21 76.7 23.7 2.1e-21 76.5 23.7 1.0 1 0 0 1 1 1 1 Membrane-associating domain Claudin_3 PF06653.11 KFR02961.1 - 0.19 11.7 13.7 0.34 10.9 13.7 1.4 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DUF3623 PF12291.8 KFR02963.1 - 0.04 13.1 0.1 0.046 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3623) CLTH PF10607.9 KFR02964.1 - 4.6e-42 143.4 0.9 3.1e-41 140.7 0.9 2.0 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 KFR02964.1 - 4.7e-26 91.2 0.2 4.7e-26 91.2 0.2 2.0 2 0 0 2 2 2 1 SPRY domain LisH PF08513.11 KFR02964.1 - 8.9e-06 25.5 0.0 2.2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 LisH PARM PF17061.5 KFR02964.1 - 0.49 10.5 21.9 0.88 9.7 21.9 1.3 1 0 0 1 1 1 0 PARM Macoilin PF09726.9 KFR02964.1 - 2.2 6.7 11.1 2.9 6.3 11.1 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 KFR02964.1 - 6.7 5.4 6.7 8.8 5.0 6.7 1.2 1 0 0 1 1 1 0 Presenilin Peptidase_S64 PF08192.11 KFR02964.1 - 9 4.6 13.9 13 4.1 13.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 TSNAXIP1_N PF15739.5 KFR02965.1 - 1e-29 103.1 7.5 1e-29 103.1 7.5 4.0 5 0 0 5 5 4 2 Translin-associated factor X-interacting N-terminus DUF2621 PF11084.8 KFR02965.1 - 0.0039 17.2 0.3 0.013 15.5 0.1 2.0 2 0 0 2 2 1 1 Protein of unknown function (DUF2621) ZapB PF06005.12 KFR02965.1 - 0.0098 16.3 2.6 0.0098 16.3 2.6 4.6 5 1 0 5 5 4 1 Cell division protein ZapB DivIC PF04977.15 KFR02965.1 - 0.021 14.6 15.7 0.51 10.2 3.5 4.6 4 0 0 4 4 4 0 Septum formation initiator bZIP_1 PF00170.21 KFR02965.1 - 0.03 14.4 1.1 0.03 14.4 1.1 5.0 5 0 0 5 5 5 0 bZIP transcription factor DUF1428 PF07237.11 KFR02965.1 - 0.047 14.0 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) HALZ PF02183.18 KFR02965.1 - 0.06 13.6 16.9 0.13 12.5 1.9 4.1 3 1 0 3 3 3 0 Homeobox associated leucine zipper DUF4600 PF15372.6 KFR02965.1 - 0.12 12.9 15.1 0.15 12.5 5.4 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4600) PI_PP_I PF18363.1 KFR02965.1 - 0.13 12.5 8.9 3.3 7.9 0.1 3.7 2 1 0 3 3 3 0 Phosphoinositide phosphatase insertion domain DUF3450 PF11932.8 KFR02965.1 - 0.56 9.5 15.4 0.17 11.2 5.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) YabA PF06156.13 KFR02965.1 - 0.66 10.7 20.2 2 9.1 0.2 4.9 5 1 0 5 5 5 0 Initiation control protein YabA DUF2353 PF09789.9 KFR02965.1 - 0.66 9.3 30.0 0.34 10.2 5.3 3.6 2 1 1 4 4 4 0 Uncharacterized coiled-coil protein (DUF2353) CCDC24 PF15669.5 KFR02965.1 - 0.91 9.4 9.3 4.6 7.1 0.1 3.1 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 24 family TPR_MLP1_2 PF07926.12 KFR02965.1 - 1.1 9.3 25.0 0.47 10.5 6.0 3.9 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein DASH_Dam1 PF08653.10 KFR02965.1 - 1.5 8.7 5.4 1.4 8.8 0.6 3.0 2 0 0 2 2 2 0 DASH complex subunit Dam1 CLZ PF16526.5 KFR02965.1 - 1.6 9.2 9.8 4.4 7.7 0.5 3.5 3 0 0 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4446 PF14584.6 KFR02965.1 - 1.9 8.5 8.5 3.1 7.8 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) FlaC_arch PF05377.11 KFR02965.1 - 3 8.3 17.8 2.7 8.4 0.2 4.4 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 KFR02965.1 - 3.4 7.7 10.4 0.92 9.5 3.6 3.1 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 KFR02965.1 - 4.3 6.6 12.1 1.1 8.5 7.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF3800 PF12686.7 KFR02965.1 - 4.7 7.9 5.0 60 4.3 0.0 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3800) CENP-T_C PF15511.6 KFR02967.1 - 1.8e-30 105.3 0.3 2.2e-30 105.0 0.3 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KFR02967.1 - 4.3e-09 36.6 0.0 5.6e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KFR02967.1 - 0.00017 21.8 0.2 0.00025 21.3 0.2 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFR02967.1 - 0.00024 21.5 0.2 0.00037 20.8 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KFR02967.1 - 0.019 15.0 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated NTF2 PF02136.20 KFR02968.1 - 9e-32 110.2 0.1 1e-31 110.0 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 KFR02968.1 - 0.036 14.5 0.0 0.043 14.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Ge1_WD40 PF16529.5 KFR02969.1 - 6.2e-140 465.8 0.3 1.4e-139 464.7 0.0 1.7 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KFR02969.1 - 0.00036 21.3 3.4 0.0067 17.3 0.1 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat ORF6C PF10552.9 KFR02969.1 - 0.026 14.6 0.6 1.6 8.9 0.0 3.3 3 0 0 3 3 3 0 ORF6C domain CelTOS PF18659.1 KFR02969.1 - 0.2 12.1 3.9 4 7.9 1.6 2.8 2 1 0 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites TetR_C_11 PF16859.5 KFR02969.1 - 1.2 9.5 4.9 2.1 8.7 0.8 2.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain INTS5_N PF14837.6 KFR02969.1 - 1.9 8.0 8.5 7.9 6.0 2.1 2.5 1 1 1 2 2 2 0 Integrator complex subunit 5 N-terminus Apolipoprotein PF01442.18 KFR02969.1 - 6.1 6.7 27.5 4.5 7.1 6.3 3.2 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain PIN_8 PF18476.1 KFR02969.1 - 6.9 6.5 17.8 5.3 6.8 3.9 3.5 1 1 3 4 4 4 0 PIN like domain Pkinase PF00069.25 KFR02970.1 - 1.8e-75 253.7 0.0 2.3e-75 253.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR02970.1 - 1.3e-35 123.0 0.0 1.7e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR02970.1 - 2.4e-07 30.4 0.1 8.5e-06 25.3 0.0 2.4 2 1 1 3 3 3 1 Kinase-like FTA2 PF13095.6 KFR02970.1 - 0.00094 18.9 0.1 0.46 10.1 0.1 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KFR02970.1 - 0.001 18.5 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFR02970.1 - 0.0016 18.4 0.1 0.43 10.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family TmoB PF06234.12 KFR02970.1 - 0.048 13.8 0.1 0.66 10.1 0.0 2.7 3 0 0 3 3 3 0 Toluene-4-monooxygenase system protein B (TmoB) Cytokin-bind PF09265.10 KFR02970.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Trypsin PF00089.26 KFR02971.1 - 3.3e-45 154.6 0.7 3.6e-45 154.5 0.7 1.0 1 0 0 1 1 1 1 Trypsin DUF316 PF03761.15 KFR02971.1 - 0.0052 16.4 0.0 0.0089 15.6 0.0 1.4 2 0 0 2 2 2 1 Chymotrypsin family Peptidase-S1 Trypsin_2 PF13365.6 KFR02971.1 - 0.012 16.5 0.0 0.015 16.2 0.0 1.2 1 0 0 1 1 1 0 Trypsin-like peptidase domain Trypsin PF00089.26 KFR02972.1 - 0.031 14.1 0.1 0.036 13.9 0.1 1.1 1 0 0 1 1 1 0 Trypsin Sec6 PF06046.13 KFR02973.1 - 1.1e-116 390.6 0.1 1.7e-116 389.9 0.1 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 Sec8_exocyst PF04048.14 KFR02973.1 - 0.011 15.6 0.3 0.39 10.6 0.2 2.7 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Enkurin PF13864.6 KFR02973.1 - 4.5 7.8 6.1 17 5.9 0.3 3.8 3 1 1 4 4 4 0 Calmodulin-binding E2F_CC-MB PF16421.5 KFR02974.1 - 5.6e-30 103.6 0.1 8.8e-30 102.9 0.1 1.3 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 KFR02974.1 - 2.2e-14 53.3 0.2 4.7e-14 52.2 0.2 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain XhlA PF10779.9 KFR02974.1 - 0.23 11.7 3.7 0.44 10.8 3.7 1.4 1 0 0 1 1 1 0 Haemolysin XhlA DUF3361 PF11841.8 KFR02975.1 - 2.2e-57 193.3 4.4 2.2e-57 193.3 4.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.13 KFR02975.1 - 5.6e-43 147.1 0.6 9.6e-43 146.3 0.6 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 KFR02975.1 - 1.1e-36 126.3 0.0 2.2e-36 125.4 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DegT_DnrJ_EryC1 PF01041.17 KFR02975.1 - 0.17 11.1 0.5 0.26 10.6 0.5 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF1704 PF08014.11 KFR02976.1 - 2.5e-12 46.5 0.1 1.6e-11 43.8 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1704) LCAT PF02450.15 KFR02977.1 - 3e-122 408.6 1.8 1.5e-121 406.2 1.8 1.8 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 KFR02977.1 - 3.3e-05 24.6 0.0 4.8e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFR02977.1 - 0.0025 17.1 0.0 0.0055 16.0 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF915 PF06028.11 KFR02977.1 - 0.0088 15.4 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) DUF900 PF05990.12 KFR02977.1 - 0.018 14.5 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF1749 PF08538.10 KFR02977.1 - 0.028 13.5 0.0 0.061 12.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) PGAP1 PF07819.13 KFR02977.1 - 0.077 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Ser_hydrolase PF06821.13 KFR02977.1 - 0.081 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase DUF676 PF05057.14 KFR02977.1 - 0.09 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) adh_short PF00106.25 KFR02978.1 - 2.6e-32 111.9 0.0 6.9e-32 110.5 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFR02978.1 - 2e-23 83.2 0.0 3.2e-23 82.5 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFR02978.1 - 2.2e-08 34.2 0.0 3.5e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 KR domain Band_7_C PF16200.5 KFR02978.1 - 0.13 12.4 0.0 0.33 11.0 0.0 1.8 1 0 0 1 1 1 0 C-terminal region of band_7 adh_short PF00106.25 KFR02979.1 - 9e-25 87.3 0.0 1.4e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFR02979.1 - 9.7e-24 84.2 0.0 1.2e-23 83.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFR02979.1 - 0.00038 20.4 0.0 0.00048 20.1 0.0 1.1 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KFR02979.1 - 0.0012 18.3 0.0 0.0074 15.7 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFR02979.1 - 0.022 14.2 0.0 0.047 13.1 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFR02979.1 - 0.089 12.7 0.0 0.11 12.4 0.0 1.4 1 1 0 1 1 1 0 NAD(P)H-binding PL48 PF15903.5 KFR02980.1 - 6.8e-171 567.9 0.1 9.6e-171 567.4 0.1 1.1 1 0 0 1 1 1 1 Filopodia upregulated, FAM65 HR1 PF02185.16 KFR02980.1 - 2.6e-05 24.3 0.1 2.6e-05 24.3 0.1 2.8 4 0 0 4 4 4 1 Hr1 repeat HEAT_2 PF13646.6 KFR02980.1 - 5.4e-05 23.5 1.9 0.0003 21.1 0.1 2.6 1 1 1 2 2 2 1 HEAT repeats Uds1 PF15456.6 KFR02980.1 - 0.042 14.0 1.3 0.064 13.4 0.1 1.9 2 0 0 2 2 2 0 Up-regulated During Septation zf-H2C2_2 PF13465.6 KFR02981.1 - 1.2e-50 167.8 95.0 1e-08 35.2 0.6 11.3 11 0 0 11 11 11 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFR02981.1 - 8e-34 114.2 102.2 8.8e-05 22.7 1.1 11.3 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR02981.1 - 5.3e-26 89.1 96.8 0.0048 17.6 2.7 11.3 11 0 0 11 11 11 10 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFR02981.1 - 1.6e-16 59.7 87.6 1.1e-06 28.3 0.6 10.6 11 0 0 11 11 11 5 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFR02981.1 - 8.6e-10 38.6 58.3 0.042 14.1 0.1 11.1 11 0 0 11 11 11 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFR02981.1 - 0.0061 16.9 1.3 0.0061 16.9 1.3 9.7 11 0 0 11 11 10 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFR02981.1 - 0.021 14.8 1.6 0.021 14.8 1.6 11.0 11 2 0 11 11 10 0 C2H2-type zinc finger C1_1 PF00130.22 KFR02981.1 - 0.49 10.3 43.8 0.34 10.8 0.9 7.7 3 2 6 9 9 9 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf_UBZ PF18439.1 KFR02981.1 - 1.3 8.6 0.0 1.3 8.6 0.0 6.9 8 1 0 8 8 8 0 Ubiquitin-Binding Zinc Finger GAGA PF09237.11 KFR02981.1 - 1.7 8.5 31.0 3.6 7.5 0.1 7.9 1 1 9 10 10 10 0 GAGA factor zf-C2H2_2 PF12756.7 KFR02981.1 - 2.9 8.3 61.6 2.4 8.6 7.0 7.5 1 1 4 6 6 6 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 KFR02981.1 - 6.8 7.5 43.9 5.4 7.8 0.9 5.9 2 1 4 6 6 6 0 zinc-ribbon family adh_short PF00106.25 KFR02983.1 - 1.7e-30 105.9 0.0 4.3e-30 104.6 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFR02983.1 - 4.3e-23 82.1 0.0 7.2e-23 81.4 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFR02983.1 - 2.1e-08 34.3 0.0 3.3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Band_7_C PF16200.5 KFR02983.1 - 0.12 12.4 0.0 0.33 11.0 0.0 1.8 1 0 0 1 1 1 0 C-terminal region of band_7 adh_short PF00106.25 KFR02984.1 - 7.4e-33 113.7 0.0 1.4e-32 112.7 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFR02984.1 - 1.7e-20 73.6 0.0 3.2e-20 72.7 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFR02984.1 - 5.5e-10 39.5 0.0 9.9e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFR02984.1 - 0.0068 16.3 0.0 0.39 10.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KFR02984.1 - 0.13 11.7 0.0 0.31 10.5 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family tRNA-synt_2c PF01411.19 KFR02985.1 - 1.8e-226 753.0 0.0 2.9e-226 752.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KFR02985.1 - 6e-17 61.5 0.1 1.4e-16 60.3 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KFR02985.1 - 1.7e-16 60.9 0.3 1.7e-16 60.9 0.3 2.0 2 0 0 2 2 2 1 DHHA1 domain Syntaxin-6_N PF09177.11 KFR02985.1 - 0.014 15.9 1.9 0.041 14.4 1.9 1.8 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Lipase_GDSL_3 PF14606.6 KFR02985.1 - 0.046 13.9 0.1 0.098 12.8 0.1 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF4404 PF14357.6 KFR02985.1 - 1.6 9.4 4.0 3.4 8.4 1.9 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) EGF_CA PF07645.15 KFR02986.1 - 2.9e-13 49.8 49.1 1e-07 32.0 0.7 5.0 5 2 0 5 5 5 3 Calcium-binding EGF domain EGF PF00008.27 KFR02986.1 - 3.6e-12 46.3 21.5 9e-09 35.5 9.8 5.5 7 1 0 7 7 7 2 EGF-like domain Sushi PF00084.20 KFR02986.1 - 1.5e-08 35.1 0.2 1.5e-08 35.1 0.2 3.1 4 0 0 4 4 4 1 Sushi repeat (SCR repeat) cEGF PF12662.7 KFR02986.1 - 2.4e-08 33.8 0.2 2.4e-08 33.8 0.2 6.6 6 0 0 6 6 6 1 Complement Clr-like EGF-like hEGF PF12661.7 KFR02986.1 - 2.9e-08 34.0 19.1 3e-06 27.6 9.6 6.1 6 0 0 6 6 6 2 Human growth factor-like EGF FXa_inhibition PF14670.6 KFR02986.1 - 1.3e-06 28.6 4.7 1.3e-06 28.6 4.7 5.1 4 1 0 4 4 4 2 Coagulation Factor Xa inhibitory site EGF_2 PF07974.13 KFR02986.1 - 0.0013 19.0 14.5 0.0013 19.0 14.5 4.9 4 1 0 4 4 4 1 EGF-like domain EGF_3 PF12947.7 KFR02986.1 - 0.95 9.7 0.0 0.95 9.7 0.0 5.6 4 2 1 5 5 5 0 EGF domain DHHC PF01529.20 KFR02987.1 - 3.9e-33 114.4 12.3 3.9e-33 114.4 12.3 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase p25-alpha PF05517.12 KFR02988.1 - 4.4e-66 221.8 9.1 5e-66 221.6 9.1 1.0 1 0 0 1 1 1 1 p25-alpha DnaB PF00772.21 KFR02988.1 - 0.0097 16.0 0.0 0.015 15.3 0.0 1.6 1 1 0 1 1 1 1 DnaB-like helicase N terminal domain BTB_2 PF02214.22 KFR02989.1 - 2.4e-12 47.0 1.1 5.2e-05 23.5 0.0 3.9 4 0 0 4 4 4 2 BTB/POZ domain TAFH PF07531.14 KFR02989.1 - 0.0036 17.4 0.0 0.0087 16.1 0.0 1.6 1 0 0 1 1 1 1 NHR1 homology to TAF Atypical_Card PF18461.1 KFR02989.1 - 0.077 13.2 0.0 0.23 11.7 0.0 1.8 1 0 0 1 1 1 0 Atypical caspase recruitment domain Na_H_Exchanger PF00999.21 KFR02991.1 - 5.4e-85 285.5 40.3 6.9e-85 285.1 40.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NEXCaM_BD PF16644.5 KFR02991.1 - 6.2e-06 26.5 2.5 1.6e-05 25.1 2.5 1.7 1 0 0 1 1 1 1 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin PIG-H PF10181.9 KFR02991.1 - 1 9.3 5.8 0.098 12.5 0.6 2.0 2 0 0 2 2 2 0 GPI-GlcNAc transferase complex, PIG-H component adh_short PF00106.25 KFR02992.1 - 1e-42 145.9 0.0 1.6e-42 145.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFR02992.1 - 3.7e-27 95.4 0.0 5.3e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFR02992.1 - 0.0012 18.8 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFR02992.1 - 0.042 13.2 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NmrA PF05368.13 KFR02992.1 - 0.098 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family vATP-synt_AC39 PF01992.16 KFR02993.1 - 5.3e-112 374.6 0.0 6e-112 374.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Nab2p_Zf1 PF18260.1 KFR02993.1 - 0.067 13.1 0.6 0.31 11.0 0.0 2.3 2 0 0 2 2 2 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 Agouti PF05039.12 KFR02994.1 - 4.7e-29 100.9 5.2 6.2e-29 100.6 5.2 1.3 1 0 0 1 1 1 1 Agouti protein Rubis-subs-bind PF09273.11 KFR02995.1 - 1.5e-17 64.5 3.7 1.5e-17 64.5 3.7 1.8 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.28 KFR02995.1 - 9.3e-16 58.7 0.1 4.7e-15 56.4 0.0 2.0 2 0 0 2 2 2 1 SET domain RNA_pol_Rpo13 PF12136.8 KFR02995.1 - 0.12 12.3 0.2 0.12 12.3 0.2 3.0 4 0 0 4 4 4 0 RNA polymerase Rpo13 subunit HTH domain Aa_trans PF01490.18 KFR02996.1 - 6.6e-55 186.5 24.4 8.1e-55 186.2 24.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KFR02996.1 - 9.9e-08 31.4 22.5 2.2e-07 30.3 16.3 2.3 2 0 0 2 2 2 2 Tryptophan/tyrosine permease family Spore_permease PF03845.13 KFR02996.1 - 0.0025 16.7 5.3 0.0025 16.7 5.3 2.5 3 0 0 3 3 3 2 Spore germination protein COXG PF06240.13 KFR02996.1 - 0.17 11.6 0.3 12 5.7 0.1 2.3 2 0 0 2 2 2 0 Carbon monoxide dehydrogenase subunit G (CoxG) SPC25 PF06703.11 KFR02996.1 - 4 7.2 6.1 12 5.7 1.0 2.6 2 1 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Aminotran_1_2 PF00155.21 KFR02997.1 - 3.5e-91 306.1 0.0 4e-91 305.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II EF-hand_1 PF00036.32 KFR02998.1 - 7.8e-26 87.7 4.3 2e-06 26.9 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KFR02998.1 - 4e-23 79.3 4.0 5.9e-06 25.8 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 KFR02998.1 - 6.7e-22 77.7 2.9 5.3e-10 39.6 0.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFR02998.1 - 1.9e-18 65.1 2.1 0.0011 18.4 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KFR02998.1 - 8e-09 35.2 2.8 0.015 15.1 0.2 4.1 2 1 1 3 3 3 3 EF-hand domain pair GPHH PF16905.5 KFR02998.1 - 0.00015 21.5 0.0 2.1 8.2 0.0 3.2 3 0 0 3 3 3 2 Voltage-dependent L-type calcium channel, IQ-associated Dockerin_1 PF00404.18 KFR02998.1 - 0.00036 20.7 0.1 2.6 8.3 0.2 3.3 3 1 0 3 3 3 2 Dockerin type I domain EF-hand_10 PF14788.6 KFR02998.1 - 0.00048 19.9 0.6 0.79 9.6 0.1 3.7 4 1 0 4 4 4 1 EF hand Caleosin PF05042.13 KFR02998.1 - 0.067 13.1 1.1 2.1 8.3 0.2 2.9 2 1 1 3 3 3 0 Caleosin related protein SPARC_Ca_bdg PF10591.9 KFR02998.1 - 0.091 13.1 0.2 16 5.8 0.1 3.3 1 1 2 3 3 2 0 Secreted protein acidic and rich in cysteine Ca binding region WWE PF02825.20 KFR02998.1 - 0.094 13.3 0.1 1.6 9.4 0.0 2.5 2 1 1 3 3 3 0 WWE domain PNP_UDP_1 PF01048.20 KFR02999.1 - 1.3e-47 162.1 0.1 1.4e-47 161.9 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily FtsJ PF01728.19 KFR03000.1 - 8.4e-30 104.2 0.0 1.1e-27 97.3 0.0 2.5 2 0 0 2 2 2 2 FtsJ-like methyltransferase Hydin_ADK PF17213.3 KFR03001.1 - 8.3e-71 238.4 2.8 8.3e-71 238.4 2.8 4.1 3 0 0 3 3 3 1 Hydin Adenylate kinase-like domain ASH PF15780.5 KFR03001.1 - 6.4e-60 199.5 42.1 3.4e-14 52.8 0.0 27.0 31 0 0 31 31 31 13 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 KFR03001.1 - 5.9e-22 77.5 3.1 0.47 10.5 0.0 17.8 19 0 0 19 19 19 3 Protein of unknown function (DUF1573) PapD-like PF14874.6 KFR03001.1 - 1.1e-17 64.1 23.9 0.35 11.1 0.0 14.8 17 0 0 17 17 17 6 Flagellar-associated PapD-like Motile_Sperm PF00635.26 KFR03001.1 - 2.1e-15 56.5 18.9 2.2 8.2 0.0 17.1 19 1 1 20 20 20 4 MSP (Major sperm protein) domain TMEM131_like PF12371.8 KFR03001.1 - 1.7e-05 25.0 19.9 0.12 12.7 0.0 12.1 14 1 1 15 15 15 2 Transmembrane protein 131-like DUF5001 PF16392.5 KFR03001.1 - 0.0085 16.0 2.3 18 5.3 0.0 6.0 5 0 0 5 5 5 1 Ig-like domain FixG_C PF11614.8 KFR03001.1 - 0.024 14.8 2.1 40 4.4 0.0 6.1 6 0 0 6 6 6 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Vac14_Fig4_bd PF11916.8 KFR03002.1 - 2.7e-79 265.0 9.7 4.6e-79 264.2 9.7 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KFR03002.1 - 1.4e-45 153.8 0.1 4.4e-40 136.2 0.0 4.3 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KFR03002.1 - 6.1e-08 32.3 0.4 0.017 15.4 0.0 4.9 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 KFR03002.1 - 2.3e-06 28.0 0.1 0.31 11.6 0.0 4.9 5 0 0 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 KFR03002.1 - 0.00082 19.4 1.8 0.89 9.6 0.1 3.8 3 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFR03002.1 - 0.0037 17.6 0.0 47 4.5 0.0 4.1 3 2 0 3 3 3 0 HEAT repeats IMD PF08397.11 KFR03003.1 - 5.5e-83 277.7 0.0 1e-82 276.8 0.0 1.4 1 1 0 1 1 1 1 IRSp53/MIM homology domain IL34 PF15036.6 KFR03004.1 - 2.1e-44 151.3 3.5 2.3e-44 151.2 3.5 1.0 1 0 0 1 1 1 1 Interleukin 34 MMS1_N PF10433.9 KFR03005.1 - 8.4e-184 611.8 0.0 2.9e-183 610.0 0.0 1.7 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KFR03005.1 - 1.1e-102 343.7 0.0 9.3e-101 337.3 0.0 2.5 2 0 0 2 2 2 2 CPSF A subunit region COG4 PF08318.12 KFR03006.1 - 3.1e-101 338.8 8.7 6.4e-101 337.8 8.7 1.6 1 0 0 1 1 1 1 COG4 transport protein Bac_thur_toxin PF01338.18 KFR03006.1 - 0.058 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacillus thuringiensis toxin COG5 PF10392.9 KFR03006.1 - 9 6.5 10.6 1.7 8.8 0.2 3.7 4 1 1 5 5 5 0 Golgi transport complex subunit 5 Fucokinase PF07959.12 KFR03007.1 - 1.5e-100 337.0 0.0 2e-100 336.6 0.0 1.1 1 0 0 1 1 1 1 L-fucokinase GHMP_kinases_N PF00288.26 KFR03007.1 - 1.3e-05 25.3 0.2 4.4e-05 23.6 0.2 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KFR03007.1 - 2.4e-05 24.6 0.0 6.6e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Glyco_transf_29 PF00777.18 KFR03008.1 - 3e-79 266.2 0.0 3.5e-79 266.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) G_glu_transpept PF01019.21 KFR03008.1 - 0.0073 15.1 0.0 0.01 14.6 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase GCV_T PF01571.21 KFR03009.1 - 2.6e-67 226.9 0.0 4.4e-67 226.1 0.0 1.4 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 KFR03009.1 - 9.5e-58 196.5 0.0 1.4e-57 195.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAO_M PF16350.5 KFR03009.1 - 4e-15 55.9 0.0 1.2e-14 54.4 0.0 1.9 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain GCV_T_C PF08669.11 KFR03009.1 - 6.7e-14 51.6 0.0 2.1e-13 50.0 0.0 1.9 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAD_binding_2 PF00890.24 KFR03009.1 - 3.4e-07 29.7 0.4 7.3e-07 28.6 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFR03009.1 - 3.5e-06 26.5 0.0 0.022 14.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFR03009.1 - 9.9e-06 25.0 0.4 0.06 12.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KFR03009.1 - 0.00014 21.3 0.2 0.17 11.3 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Trp_halogenase PF04820.14 KFR03009.1 - 0.00023 20.1 1.0 0.027 13.4 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KFR03009.1 - 0.0041 16.4 2.9 0.044 13.0 3.0 2.3 2 1 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KFR03009.1 - 0.0095 14.7 0.9 0.02 13.6 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 KFR03009.1 - 0.018 15.3 0.2 0.063 13.5 0.2 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFR03009.1 - 0.019 15.5 1.8 6 7.5 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFR03009.1 - 0.021 14.0 1.3 0.32 10.2 0.2 2.2 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.7 KFR03009.1 - 0.039 13.3 2.3 0.082 12.2 2.3 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 KFR03009.1 - 0.096 12.9 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 KFR03009.1 - 0.2 11.7 0.1 0.46 10.5 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Cys_rich_FGFR PF00839.17 KFR03010.1 - 1.7e-202 655.8 115.6 2.2e-17 63.0 1.8 15.2 15 0 0 15 15 15 15 Cysteine rich repeat IFT43 PF15305.6 KFR03010.1 - 0.06 13.5 0.3 0.22 11.7 0.1 2.0 2 0 0 2 2 2 0 Intraflagellar transport protein 43 DUF445 PF04286.12 KFR03010.1 - 4 7.2 8.0 5.3 6.7 5.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF445) zf-RING_2 PF13639.6 KFR03011.1 - 7.9e-09 35.7 2.7 7.9e-09 35.7 2.7 3.1 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 KFR03011.1 - 3.2e-08 33.3 1.2 3.2e-08 33.3 1.2 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFR03011.1 - 6.2e-07 29.2 1.1 6.2e-07 29.2 1.1 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFR03011.1 - 1.2e-06 28.3 2.2 1.2e-06 28.3 2.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFR03011.1 - 3.7e-06 26.9 0.5 3.7e-06 26.9 0.5 2.3 2 0 0 2 2 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KFR03011.1 - 0.00012 22.2 5.1 0.00012 22.2 5.1 3.0 3 1 0 3 3 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KFR03011.1 - 0.00014 21.5 0.6 0.00079 19.1 0.6 2.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 KFR03011.1 - 0.00025 20.9 2.8 0.00025 20.9 2.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFR03011.1 - 0.00082 19.2 1.7 0.004 17.0 1.7 2.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Rtf2 PF04641.12 KFR03011.1 - 0.002 17.6 2.0 0.0038 16.6 2.0 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_4 PF15227.6 KFR03011.1 - 0.0052 16.9 1.6 0.0052 16.9 1.6 2.9 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KFR03011.1 - 0.011 15.8 2.3 0.071 13.2 2.3 2.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KFR03011.1 - 0.021 14.6 2.8 0.021 14.6 2.8 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 KFR03011.1 - 0.034 14.3 0.4 0.034 14.3 0.4 2.0 2 0 0 2 2 1 0 Zinc-binding RING-finger FANCL_C PF11793.8 KFR03011.1 - 0.25 11.5 6.4 3.3 7.9 6.4 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain FAD-SLDH PF12318.8 KFR03011.1 - 0.94 9.5 3.3 1 9.4 1.5 2.0 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Pkinase_Tyr PF07714.17 KFR03012.1 - 1.9e-43 148.7 0.1 3.6e-41 141.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFR03012.1 - 2.6e-28 99.1 0.0 8.8e-28 97.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain RPW8 PF05659.11 KFR03012.1 - 0.00067 19.4 1.5 0.00067 19.4 1.5 1.9 2 0 0 2 2 2 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 Glu-tRNAGln PF02686.15 KFR03012.1 - 0.054 13.8 0.1 0.18 12.1 0.1 1.9 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit CENP-F_leu_zip PF10473.9 KFR03012.1 - 0.54 10.3 5.7 0.7 9.9 0.2 2.7 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FA_hydroxylase PF04116.13 KFR03013.1 - 1.7e-16 60.8 10.9 1.7e-16 60.8 10.9 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily COX14 PF14880.6 KFR03013.1 - 0.12 12.2 8.2 0.1 12.5 3.5 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Anth_synt_I_N PF04715.13 KFR03013.1 - 0.14 12.3 2.4 0.34 11.1 2.4 1.7 1 1 0 1 1 1 0 Anthranilate synthase component I, N terminal region Cyt-b5 PF00173.28 KFR03013.1 - 0.21 11.7 1.0 0.32 11.1 0.0 1.9 2 0 0 2 2 2 0 Cytochrome b5-like Heme/Steroid binding domain TMEM189_B_dmain PF10520.9 KFR03013.1 - 2.3 8.3 7.2 0.61 10.2 0.9 2.2 2 0 0 2 2 2 0 B domain of TMEM189, localisation domain Ig_3 PF13927.6 KFR03023.1 - 1.2e-27 96.2 0.8 9.6e-11 42.1 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.12 KFR03023.1 - 2.5e-20 72.3 0.8 2.3e-16 59.6 0.2 3.6 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 KFR03023.1 - 2e-19 69.7 1.3 8.1e-08 32.5 0.0 4.0 4 1 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 KFR03023.1 - 2.3e-18 66.1 0.8 1.2e-05 25.4 0.0 3.6 4 0 0 4 4 4 3 Immunoglobulin domain I-set PF07679.16 KFR03023.1 - 1.4e-17 63.5 0.2 1.9e-06 27.9 0.0 3.9 3 1 0 3 3 3 3 Immunoglobulin I-set domain V-set PF07686.17 KFR03023.1 - 1.8e-05 24.9 5.5 0.065 13.4 0.1 5.0 4 2 0 4 4 4 1 Immunoglobulin V-set domain C1-set PF07654.15 KFR03023.1 - 0.00027 21.2 1.2 0.0065 16.8 0.1 3.0 3 0 0 3 3 3 1 Immunoglobulin C1-set domain Ig_4 PF16680.5 KFR03023.1 - 0.00077 19.7 0.4 1.6 9.1 0.1 3.4 3 1 1 4 4 4 2 T-cell surface glycoprotein CD3 delta chain Insulin_TMD PF17870.1 KFR03023.1 - 0.014 15.5 1.8 0.026 14.6 1.8 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment FeoB_associated PF12669.7 KFR03023.1 - 0.028 14.8 2.1 0.055 13.9 2.1 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein 4HB_MCP_1 PF12729.7 KFR03023.1 - 3.3 7.2 4.4 2.5 7.6 0.0 2.1 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction zf-C3HC4_3 PF13920.6 KFR03024.1 - 1.5e-13 50.4 12.7 2.7e-13 49.5 12.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFR03024.1 - 1.8e-07 30.9 10.3 3.4e-07 30.0 10.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFR03024.1 - 0.019 14.9 12.6 0.042 13.8 12.5 1.7 1 1 0 1 1 1 0 zinc-RING finger domain Pox_P35 PF03213.14 KFR03024.1 - 0.92 8.7 6.3 1.3 8.1 6.3 1.2 1 0 0 1 1 1 0 Poxvirus P35 protein C1q PF00386.21 KFR03025.1 - 3.4e-37 127.5 0.0 4.1e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFR03025.1 - 3.4e-10 39.5 32.7 8.3e-08 31.9 32.7 2.2 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) FSAP_sig_propep PF03032.15 KFR03025.1 - 0.092 12.8 0.5 0.14 12.2 0.5 1.3 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide T3SS_NleG PF06416.12 KFR03025.1 - 0.26 11.2 0.0 0.39 10.7 0.0 1.2 1 0 0 1 1 1 0 Effector protein NleG CUB PF00431.20 KFR03027.1 - 6.3e-25 87.7 0.0 9.7e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 CUB domain Fz PF01392.22 KFR03027.1 - 2.8e-24 85.9 0.5 2.8e-24 85.9 0.5 1.7 2 0 0 2 2 2 1 Fz domain Ldl_recept_a PF00057.18 KFR03027.1 - 2.2e-10 40.5 8.8 2.2e-10 40.5 8.8 2.3 2 1 0 2 2 2 1 Low-density lipoprotein receptor domain class A V-set PF07686.17 KFR03028.1 - 1.4e-06 28.4 0.6 2.4e-06 27.7 0.6 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFR03028.1 - 2.2e-06 27.7 0.2 3.8e-06 27.0 0.2 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFR03028.1 - 0.00012 22.6 0.2 0.00018 22.0 0.2 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFR03028.1 - 0.014 15.7 1.3 0.026 14.8 1.3 1.4 1 1 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFR03028.1 - 0.015 15.3 0.3 0.027 14.5 0.3 1.6 1 1 0 1 1 1 0 Immunoglobulin I-set domain Herpes_gE PF02480.16 KFR03028.1 - 0.052 12.3 0.7 0.062 12.1 0.7 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Izumo-Ig PF16706.5 KFR03028.1 - 0.066 13.3 0.2 0.11 12.5 0.2 1.6 1 1 0 1 1 1 0 Izumo-like Immunoglobulin domain PAN_4 PF14295.6 KFR03028.1 - 0.068 13.1 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 PAN domain RAI1 PF08652.11 KFR03028.1 - 0.17 12.1 0.9 1.8 8.8 0.2 2.2 1 1 1 2 2 2 0 RAI1 like PD-(D/E)XK nuclease TMEM52 PF14979.6 KFR03031.1 - 0.0019 18.1 1.3 0.0026 17.7 1.3 1.2 1 0 0 1 1 1 1 Transmembrane 52 TMEM154 PF15102.6 KFR03031.1 - 0.0032 17.4 0.1 0.0041 17.0 0.1 1.1 1 0 0 1 1 1 1 TMEM154 protein family EGF PF00008.27 KFR03031.1 - 0.0039 17.4 2.8 0.0039 17.4 2.8 2.4 2 0 0 2 2 2 1 EGF-like domain EphA2_TM PF14575.6 KFR03031.1 - 0.0053 17.6 0.3 0.0088 16.9 0.3 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 KFR03031.1 - 0.0077 16.5 0.5 0.0077 16.5 0.5 1.3 2 0 0 2 2 1 1 Wnt and FGF inhibitory regulator PAG PF15347.6 KFR03031.1 - 0.015 14.4 0.3 0.018 14.0 0.3 1.0 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched Vpu PF00558.19 KFR03031.1 - 0.015 15.0 0.2 0.021 14.6 0.2 1.2 1 0 0 1 1 1 0 Vpu protein Comm PF15957.5 KFR03031.1 - 0.036 14.4 0.1 0.053 13.9 0.1 1.2 1 0 0 1 1 1 0 Commissureless DUF2663 PF10864.8 KFR03031.1 - 0.041 14.3 0.0 0.054 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) Rax2 PF12768.7 KFR03031.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity LRR19-TM PF15176.6 KFR03031.1 - 0.14 12.2 0.2 0.21 11.6 0.2 1.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Sigma_reg_N PF13800.6 KFR03031.1 - 0.14 12.5 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal zinc_ribbon_6 PF14599.6 KFR03033.1 - 5.3e-29 100.0 2.2 5.3e-29 100.0 2.2 3.5 3 1 1 4 4 3 1 Zinc-ribbon zf-RING_2 PF13639.6 KFR03033.1 - 1.5e-10 41.2 5.3 1.5e-10 41.2 5.3 4.4 3 2 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.25 KFR03033.1 - 1.7e-07 31.0 4.5 1.7e-07 31.0 4.5 4.4 3 2 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFR03033.1 - 8.8e-07 28.7 5.6 8.8e-07 28.7 5.6 4.5 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFR03033.1 - 2.1e-06 27.6 4.9 2.1e-06 27.6 4.9 5.6 2 2 3 5 5 4 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFR03033.1 - 2.3e-06 27.5 1.4 2.3e-06 27.5 1.4 4.3 6 1 0 6 6 6 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFR03033.1 - 1.6e-05 24.6 0.7 1.6e-05 24.6 0.7 5.1 3 3 2 5 5 4 2 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFR03033.1 - 2.2e-05 24.2 6.1 2.2e-05 24.2 6.1 5.2 2 2 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFR03033.1 - 7.4e-05 22.4 3.1 7.4e-05 22.4 3.1 4.2 4 1 0 4 4 4 1 RING-like zinc finger zf-RING_4 PF14570.6 KFR03033.1 - 0.00019 21.1 3.0 0.00019 21.1 3.0 4.5 4 2 0 4 4 3 1 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 KFR03033.1 - 0.00021 21.3 1.0 0.00021 21.3 1.0 3.1 3 2 0 3 3 3 1 Zinc-binding RING-finger zf-CHY PF05495.12 KFR03033.1 - 0.036 14.6 1.8 0.036 14.6 1.8 4.2 2 1 1 3 3 2 0 CHY zinc finger Pkinase PF00069.25 KFR03034.1 - 7.9e-76 254.9 0.0 1.2e-75 254.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR03034.1 - 1.3e-40 139.3 0.0 6.3e-40 137.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFR03034.1 - 3.2e-05 23.1 0.1 6.7e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFR03034.1 - 4.9e-05 22.8 1.4 0.00043 19.7 0.0 2.6 2 1 0 3 3 3 1 Kinase-like RIO1 PF01163.22 KFR03034.1 - 0.00055 19.6 0.1 0.0013 18.3 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KFR03034.1 - 0.0015 17.9 0.3 0.0046 16.3 0.1 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFR03034.1 - 0.039 13.9 0.0 0.25 11.2 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family AP1AR PF15745.5 KFR03035.1 - 6.4e-151 501.6 16.5 7.2e-151 501.4 16.5 1.0 1 0 0 1 1 1 1 AP-1 complex-associated regulatory protein PA26 PF04636.13 KFR03035.1 - 6 5.7 8.7 2.3 7.0 6.3 1.4 1 1 0 1 1 1 0 PA26 p53-induced protein (sestrin) FHA PF00498.26 KFR03036.1 - 0.0055 17.0 0.0 0.0076 16.6 0.0 1.2 1 0 0 1 1 1 1 FHA domain MMS1_N PF10433.9 KFR03036.1 - 0.063 11.9 0.0 0.069 11.8 0.0 1.1 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Alpha_kinase PF02816.18 KFR03037.1 - 5.2e-47 160.4 1.3 1.4e-46 159.0 1.3 1.8 1 0 0 1 1 1 1 Alpha-kinase family AAA_12 PF13087.6 KFR03038.1 - 8.9e-53 178.9 0.2 2.8e-52 177.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KFR03038.1 - 2.4e-26 93.1 0.0 5.7e-19 68.9 0.2 2.5 1 1 1 2 2 2 2 AAA domain zf-GRF PF06839.12 KFR03038.1 - 1.5e-13 50.6 0.1 3.4e-13 49.4 0.1 1.6 1 0 0 1 1 1 1 GRF zinc finger Viral_helicase1 PF01443.18 KFR03038.1 - 1.8e-09 37.7 0.1 0.0024 17.6 0.1 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KFR03038.1 - 0.0021 17.8 0.0 0.03 14.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFR03038.1 - 0.011 16.1 0.0 0.04 14.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.6 KFR03038.1 - 0.011 15.5 0.1 0.034 14.0 0.1 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 KFR03038.1 - 0.022 14.2 0.0 5.2 6.3 0.0 2.5 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain DUF2439 PF10382.9 KFR03039.1 - 6.6e-17 61.6 0.1 1.5e-16 60.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) RRM_3 PF08777.11 KFR03040.1 - 5.2e-29 100.3 0.1 5.2e-29 100.3 0.1 4.0 5 0 0 5 5 5 2 RNA binding motif La PF05383.17 KFR03040.1 - 7.6e-21 73.9 0.7 2.2e-20 72.4 0.1 2.1 2 0 0 2 2 2 1 La domain RRM_1 PF00076.22 KFR03040.1 - 5e-19 67.9 0.1 8.6e-16 57.5 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.7 KFR03041.1 - 4e-146 476.0 42.9 2e-17 63.6 0.1 12.1 1 1 11 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.30 KFR03041.1 - 2.6e-130 419.7 62.9 1.1e-06 28.8 0.4 23.3 23 0 0 23 23 23 21 Ankyrin repeat Ank_5 PF13857.6 KFR03041.1 - 1.2e-119 388.8 39.3 1.6e-10 41.0 0.3 17.7 2 2 17 20 20 20 19 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFR03041.1 - 1.7e-119 388.8 32.9 2.7e-12 46.9 0.1 15.0 5 3 12 18 18 18 18 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFR03041.1 - 1.4e-107 338.5 32.6 7.4e-05 22.9 0.0 23.9 24 0 0 24 24 24 19 Ankyrin repeat UPA_2 PF17809.1 KFR03041.1 - 6e-54 181.4 0.1 1.6e-53 180.0 0.1 1.8 1 0 0 1 1 1 1 UPA domain ZU5 PF00791.20 KFR03041.1 - 1.1e-33 115.5 2.9 5.2e-26 90.9 0.0 3.7 4 0 0 4 4 4 2 ZU5 domain Death PF00531.22 KFR03041.1 - 2e-21 76.0 1.4 5.4e-21 74.5 1.4 1.8 1 0 0 1 1 1 1 Death domain PK_C PF02887.16 KFR03041.1 - 0.00016 21.9 1.6 9.1 6.6 0.0 5.4 5 1 0 5 5 5 1 Pyruvate kinase, alpha/beta domain RhoGAP PF00620.27 KFR03045.1 - 3.1e-30 105.0 2.3 3.3e-29 101.7 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 KFR03045.1 - 2.5e-20 72.9 0.7 4.6e-20 72.1 0.0 1.8 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 KFR03045.1 - 3e-05 24.2 0.6 0.00068 19.9 0.6 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFR03045.1 - 0.0007 20.0 4.8 0.02 15.3 4.8 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 KFR03045.1 - 0.028 14.8 3.0 0.26 11.7 0.1 3.0 3 0 0 3 3 3 0 Pleckstrin homology domain Tropomyosin_1 PF12718.7 KFR03045.1 - 0.096 12.8 16.6 0.15 12.2 16.6 1.3 1 0 0 1 1 1 0 Tropomyosin like Nsp1_C PF05064.13 KFR03045.1 - 0.14 11.9 10.0 0.87 9.4 10.3 2.1 2 0 0 2 2 2 0 Nsp1-like C-terminal region ADIP PF11559.8 KFR03045.1 - 0.18 11.9 8.3 0.43 10.6 8.3 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Cnn_1N PF07989.11 KFR03045.1 - 0.89 9.8 15.6 0.34 11.1 12.3 2.1 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Jnk-SapK_ap_N PF09744.9 KFR03045.1 - 3 8.1 17.0 39 4.4 15.8 2.3 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Vac_Fusion PF02346.16 KFR03045.1 - 3.5 7.3 5.0 1.7 8.3 0.6 2.6 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 FlaC_arch PF05377.11 KFR03045.1 - 5.4 7.5 14.9 4.8 7.6 1.9 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) LRR_8 PF13855.6 KFR03046.1 - 1.6e-58 194.3 33.5 3.3e-15 55.6 4.0 5.2 2 2 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFR03046.1 - 5.1e-29 99.9 31.9 1.9e-07 31.3 0.9 5.9 2 1 6 8 8 8 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFR03046.1 - 9.1e-18 64.4 0.0 5.5e-13 49.0 0.0 2.4 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) I-set PF07679.16 KFR03046.1 - 1.6e-13 50.6 0.0 2.3e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_9 PF14580.6 KFR03046.1 - 3.9e-13 49.3 2.0 2.2e-07 30.5 0.7 2.2 1 1 1 2 2 2 2 Leucine-rich repeat Ig_3 PF13927.6 KFR03046.1 - 5.1e-12 46.2 0.1 9.4e-12 45.4 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFR03046.1 - 6.2e-09 35.9 0.2 1.1e-08 35.2 0.2 1.4 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.33 KFR03046.1 - 3.7e-08 32.8 22.8 0.15 12.7 0.0 8.5 8 1 0 8 8 8 3 Leucine Rich Repeat V-set PF07686.17 KFR03046.1 - 5e-06 26.7 0.5 0.00014 22.0 0.5 2.3 1 1 0 1 1 1 1 Immunoglobulin V-set domain LRRNT PF01462.18 KFR03046.1 - 1.7e-05 24.3 1.9 1.7e-05 24.3 1.9 2.5 3 0 0 3 3 2 1 Leucine rich repeat N-terminal domain Ig_2 PF13895.6 KFR03046.1 - 0.00016 21.9 0.1 0.00034 20.9 0.1 1.6 1 1 0 1 1 1 1 Immunoglobulin domain LRR_6 PF13516.6 KFR03046.1 - 0.00028 20.7 19.5 17 5.7 0.1 8.1 8 0 0 8 8 8 0 Leucine Rich repeat Ig_6 PF18452.1 KFR03046.1 - 0.0017 17.9 0.8 0.0059 16.1 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Ank PF00023.30 KFR03063.1 - 1.1e-29 101.5 2.3 4.2e-06 27.0 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KFR03063.1 - 3.6e-27 94.4 4.6 7.7e-08 32.7 0.2 5.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFR03063.1 - 7.3e-27 93.8 1.9 5.6e-12 46.1 0.0 2.9 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFR03063.1 - 4.2e-22 77.9 5.3 5.9e-11 42.4 0.7 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFR03063.1 - 4.4e-22 75.8 4.9 0.00041 20.6 0.0 5.1 6 0 0 6 6 6 4 Ankyrin repeat SOCS_box PF07525.16 KFR03063.1 - 6.9e-09 35.9 0.6 1.4e-08 34.9 0.6 1.6 1 0 0 1 1 1 1 SOCS box PFK PF00365.20 KFR03064.1 - 3.8e-70 236.4 0.0 5.4e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 Phosphofructokinase PFK PF00365.20 KFR03065.1 - 1.7e-39 135.8 0.1 1.9e-39 135.7 0.1 1.0 1 0 0 1 1 1 1 Phosphofructokinase Peptidase_C48 PF02902.19 KFR03066.1 - 3.3e-47 161.1 1.4 5.8e-47 160.3 1.4 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.13 KFR03066.1 - 0.02 13.6 2.0 1.9 7.1 0.0 2.5 3 0 0 3 3 3 0 Vaccinia virus I7 processing peptidase COLFI PF01410.18 KFR03067.1 - 3e-58 196.9 0.0 3.2e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain DUF1356 PF07092.12 KFR03068.1 - 1.1e-103 345.6 9.1 1.2e-103 345.4 9.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) Anti-TRAP PF15777.5 KFR03068.1 - 0.00024 21.0 0.2 0.00042 20.2 0.2 1.3 1 0 0 1 1 1 1 Tryptophan RNA-binding attenuator protein inhibitory protein LEA_2 PF03168.13 KFR03068.1 - 0.00028 21.4 0.4 0.00048 20.6 0.4 1.3 1 0 0 1 1 1 1 Late embryogenesis abundant protein FAM196 PF15265.6 KFR03068.1 - 0.36 10.3 0.7 0.54 9.7 0.7 1.2 1 0 0 1 1 1 0 FAM196 family zf-C4 PF00105.18 KFR03069.1 - 7.9e-29 99.9 15.8 1.3e-28 99.2 15.8 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFR03069.1 - 9.2e-24 84.2 1.3 2.9e-23 82.5 0.2 2.0 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-RRPl_C4 PF17026.5 KFR03069.1 - 0.052 13.7 3.5 0.097 12.8 3.5 1.5 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type UPF0160 PF03690.13 KFR03070.1 - 2.6e-118 395.3 0.0 3e-118 395.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) ANAPC4_WD40 PF12894.7 KFR03071.1 - 1.5e-12 47.7 0.1 0.018 15.3 0.0 6.3 3 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFR03071.1 - 2.9e-09 37.4 5.4 5e-05 24.0 0.0 5.3 6 0 0 6 6 6 1 WD domain, G-beta repeat eIF2A PF08662.11 KFR03071.1 - 1.8e-07 31.2 0.1 0.011 15.6 0.0 3.5 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KFR03071.1 - 0.0003 20.6 0.2 0.38 10.8 0.1 3.2 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat WDCP PF15390.6 KFR03071.1 - 0.00059 18.4 8.2 0.024 13.1 3.2 2.6 1 1 2 3 3 3 2 WD repeat and coiled-coil-containing protein family DPPIV_N PF00930.21 KFR03071.1 - 0.22 10.2 0.0 2.7 6.6 0.0 2.5 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region zf-C2H2 PF00096.26 KFR03072.1 - 5.8e-18 64.3 16.8 6.8e-07 29.4 0.6 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFR03072.1 - 6.6e-15 54.8 10.2 5.4e-08 32.9 0.8 3.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR03072.1 - 3.2e-11 43.1 16.9 0.00041 21.0 0.7 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFR03072.1 - 1.5e-06 28.3 5.3 0.034 14.4 2.7 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFR03072.1 - 0.00017 21.9 5.6 0.17 12.3 1.6 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-LYAR PF08790.11 KFR03072.1 - 0.00039 20.3 6.6 0.0096 15.8 1.0 3.0 3 0 0 3 3 3 2 LYAR-type C2HC zinc finger zf-BED PF02892.15 KFR03072.1 - 0.004 17.2 11.1 0.075 13.1 3.0 3.1 1 1 2 3 3 3 1 BED zinc finger zf-C2H2_6 PF13912.6 KFR03072.1 - 0.0063 16.5 15.8 0.38 10.8 0.1 3.7 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFR03072.1 - 0.012 15.9 4.6 0.013 15.8 4.6 1.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-Di19 PF05605.12 KFR03072.1 - 0.02 15.2 4.4 0.027 14.8 2.6 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 KFR03072.1 - 0.038 14.5 4.8 0.39 11.2 0.1 3.2 3 2 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_2 PF12756.7 KFR03072.1 - 0.047 14.0 4.9 1.4 9.3 1.3 2.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) C2-set_2 PF08205.12 KFR03072.1 - 0.058 13.5 0.4 9.9 6.3 0.4 2.1 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain FOXP-CC PF16159.5 KFR03072.1 - 0.3 11.8 5.6 1.1 9.9 0.4 2.8 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 KFR03072.1 - 1.3 8.8 11.0 4.4 7.2 0.2 2.8 3 0 0 3 3 3 0 zinc-finger C2H2-type zf_C2H2_ZHX PF18387.1 KFR03072.1 - 1.4 8.6 7.9 0.61 9.8 0.7 2.7 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 KFR03073.1 - 1.8e-14 53.4 25.4 9.8e-08 32.1 3.0 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFR03073.1 - 1.9e-13 50.0 26.7 2.2e-05 24.6 0.8 4.4 3 1 1 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR03073.1 - 4.2e-08 33.3 25.4 0.00034 21.2 1.7 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFR03073.1 - 0.01 16.1 3.4 2.1 8.7 0.8 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KFR03073.1 - 0.014 15.7 3.1 0.049 13.9 3.1 2.0 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-Di19 PF05605.12 KFR03073.1 - 6.9 7.0 13.8 3.5 8.0 2.7 3.2 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding KH_1 PF00013.29 KFR03074.1 - 3.7e-50 167.6 15.7 4e-18 65.0 0.8 3.1 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KFR03074.1 - 3e-15 55.8 6.9 4.1e-05 23.3 0.0 3.6 3 1 1 4 4 4 3 KH domain KH_4 PF13083.6 KFR03074.1 - 1.2e-07 31.5 4.1 0.064 13.1 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KFR03074.1 - 1.8e-05 24.7 7.1 0.28 11.3 0.1 3.4 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 KFR03074.1 - 0.014 15.4 0.1 0.27 11.2 0.0 2.7 3 1 0 3 3 3 0 KH-like RNA-binding domain Pkinase PF00069.25 KFR03075.1 - 1.3e-51 175.5 0.0 1.5e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR03075.1 - 3.7e-49 167.3 0.0 4.6e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFR03075.1 - 0.0021 16.9 0.0 0.0029 16.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFR03075.1 - 0.073 13.0 0.0 0.26 11.2 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KFR03075.1 - 0.12 12.0 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family bZIP_1 PF00170.21 KFR03077.1 - 6e-13 48.7 7.6 8.8e-13 48.1 7.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFR03077.1 - 2.9e-09 36.9 7.9 5.5e-09 36.0 7.9 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFR03077.1 - 8e-05 23.1 6.9 0.00014 22.3 6.9 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Cnn_1N PF07989.11 KFR03077.1 - 0.026 14.7 1.7 0.042 14.0 1.7 1.3 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 NDUFB11 PF17250.2 KFR03077.1 - 0.22 12.2 0.4 0.39 11.4 0.4 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase 11 kDa subunit GIT_CC PF16559.5 KFR03077.1 - 0.26 11.2 3.0 0.49 10.3 3.0 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Lamprin PF06403.11 KFR03081.1 - 0.00011 22.2 7.4 0.00029 20.8 7.4 1.6 1 1 0 1 1 1 1 Lamprin Chorion_1 PF01723.16 KFR03081.1 - 0.02 14.9 18.5 1.9 8.4 18.5 2.0 1 1 0 1 1 1 0 Chorion protein Homeodomain PF00046.29 KFR03082.1 - 2.5e-19 68.9 7.6 3e-19 68.6 7.6 1.1 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFR03082.1 - 2.1e-05 24.3 2.1 3.9e-05 23.4 2.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain DUF1510 PF07423.11 KFR03082.1 - 0.028 14.6 0.0 0.03 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1510) Homez PF11569.8 KFR03082.1 - 0.052 13.0 0.1 0.071 12.6 0.1 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Homeodomain PF00046.29 KFR03084.1 - 4.6e-20 71.2 7.0 5e-20 71.1 7.0 1.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFR03084.1 - 0.00069 19.5 1.4 0.0011 18.8 1.4 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 KFR03084.1 - 0.0056 16.1 0.2 0.0073 15.7 0.2 1.2 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez DUF3528 PF12045.8 KFR03085.1 - 4.9e-60 202.2 1.9 7.8e-60 201.6 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3528) Homeodomain PF00046.29 KFR03085.1 - 1.9e-19 69.2 8.3 3.2e-19 68.5 8.3 1.4 1 0 0 1 1 1 1 Homeodomain Baculo_p74_N PF08404.10 KFR03085.1 - 0.0033 16.6 0.1 0.0048 16.0 0.1 1.2 1 0 0 1 1 1 1 Baculoviridae P74 N-terminal Homeobox_KN PF05920.11 KFR03085.1 - 0.032 14.1 0.7 0.072 13.0 0.7 1.6 1 0 0 1 1 1 0 Homeobox KN domain Auxin_canalis PF05703.11 KFR03085.1 - 5.4 6.9 6.4 8.1 6.3 6.4 1.5 1 1 0 1 1 1 0 Auxin canalisation 7tm_4 PF13853.6 KFR03107.1 - 3.7e-43 148.3 10.2 3.7e-25 89.2 3.1 2.0 1 1 1 2 2 2 2 Olfactory receptor 7tm_1 PF00001.21 KFR03107.1 - 1.2e-26 93.6 15.0 2e-25 89.6 15.0 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR03107.1 - 0.0001 21.8 7.6 0.00025 20.5 7.6 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFR03107.1 - 0.0011 18.7 4.4 0.0011 18.7 4.4 1.8 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx CholecysA-Rec_N PF09193.10 KFR03107.1 - 0.021 14.8 0.0 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Cholecystokinin A receptor, N-terminal Lig_C PF18330.1 KFR03112.1 - 0.089 12.8 0.1 0.11 12.6 0.1 1.1 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region WW PF00397.26 KFR03117.1 - 1.5e-09 37.7 0.4 2.4e-09 37.1 0.4 1.3 1 0 0 1 1 1 1 WW domain Synaphin PF05835.12 KFR03141.1 - 3.4e-34 118.2 14.7 3.8e-34 118.0 14.7 1.0 1 0 0 1 1 1 1 Synaphin protein Presenilin PF01080.17 KFR03141.1 - 7.5 5.2 5.2 8.2 5.1 5.2 1.0 1 0 0 1 1 1 0 Presenilin RAWUL PF16207.5 KFR03142.1 - 4.1e-16 59.4 0.8 1.1e-15 58.1 0.3 2.0 2 1 0 2 2 2 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 KFR03142.1 - 8.7e-12 44.7 8.1 2.1e-11 43.5 8.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFR03142.1 - 4e-09 36.2 9.3 4e-09 36.2 9.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFR03142.1 - 1e-07 32.1 8.0 1e-07 32.1 8.0 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFR03142.1 - 2.9e-06 27.1 8.4 2.9e-06 27.1 8.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFR03142.1 - 2.5e-05 24.2 4.7 2.5e-05 24.2 4.7 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFR03142.1 - 2.7e-05 24.0 9.5 2.7e-05 24.0 9.5 2.5 2 1 1 3 3 3 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFR03142.1 - 6.4e-05 23.2 4.9 6.4e-05 23.2 4.9 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KFR03142.1 - 0.00059 19.9 8.6 0.00059 19.9 8.6 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KFR03142.1 - 0.01 15.6 9.4 0.014 15.2 6.3 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 KFR03142.1 - 0.021 14.6 3.3 0.038 13.8 3.3 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KFR03142.1 - 0.029 14.2 9.8 0.029 14.2 9.8 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 GAGA PF09237.11 KFR03142.1 - 0.031 14.1 0.1 0.099 12.5 0.1 1.8 1 0 0 1 1 1 0 GAGA factor DUF3337 PF11816.8 KFR03142.1 - 0.032 14.1 5.5 0.035 14.0 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3337) zf-RING_10 PF16685.5 KFR03142.1 - 0.17 12.0 10.4 0.092 12.9 5.9 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 DZR PF12773.7 KFR03142.1 - 0.81 9.8 9.8 0.93 9.6 5.8 2.4 2 0 0 2 2 2 0 Double zinc ribbon DUF1272 PF06906.11 KFR03142.1 - 1.1 9.5 9.4 0.77 9.9 6.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) MFS_1 PF07690.16 KFR03143.1 - 3.8e-23 82.0 23.4 4.8e-23 81.6 23.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Zip PF02535.22 KFR03143.1 - 0.019 14.2 1.9 0.4 9.9 1.5 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter PGF-CTERM PF18204.1 KFR03143.1 - 6.7 6.8 9.6 1.4 9.0 3.2 2.9 2 0 0 2 2 2 0 PGF-CTERM motif TraB PF01963.17 KFR03144.1 - 1.1e-22 81.2 0.0 1.2e-22 81.1 0.0 1.0 1 0 0 1 1 1 1 TraB family TraB PF01963.17 KFR03145.1 - 3.2e-38 132.2 0.0 3.6e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 TraB family Phosphodiest PF01663.22 KFR03147.1 - 4e-11 43.1 0.4 8.4e-08 32.2 0.1 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KFR03147.1 - 0.051 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Metalloenzyme superfamily Pkinase PF00069.25 KFR03148.1 - 4e-46 157.5 0.0 6.4e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PTEN_C2 PF10409.9 KFR03148.1 - 2.9e-30 104.8 0.1 6.9e-30 103.5 0.1 1.7 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Pkinase_Tyr PF07714.17 KFR03148.1 - 1.1e-26 93.7 0.0 1.7e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DnaJ PF00226.31 KFR03148.1 - 1.9e-06 27.9 0.0 5.4e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain Haspin_kinase PF12330.8 KFR03148.1 - 1.8e-05 23.8 0.0 3.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain DSPc PF00782.20 KFR03148.1 - 0.049 13.4 0.4 0.14 12.0 0.4 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Kinase-like PF14531.6 KFR03148.1 - 0.051 12.9 0.0 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 KFR03148.1 - 0.1 11.6 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KFR03148.1 - 0.23 11.4 0.0 0.47 10.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Y_phosphatase PF00102.27 KFR03148.1 - 0.3 10.6 2.0 0.28 10.7 0.2 1.9 2 0 0 2 2 2 0 Protein-tyrosine phosphatase S-AdoMet_synt_C PF02773.16 KFR03149.1 - 1.7e-65 219.2 0.0 3.8e-65 218.0 0.0 1.5 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KFR03149.1 - 4.3e-42 143.1 0.0 9.7e-42 142.0 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KFR03149.1 - 1.5e-39 134.7 0.6 3.3e-39 133.5 0.6 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain UPF0270 PF06794.12 KFR03149.1 - 0.16 12.1 0.3 8.5 6.5 0.0 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0270) DUF1211 PF06736.11 KFR03150.1 - 3.1e-36 123.7 8.7 1.7e-22 79.6 0.0 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1211) PDEase_I PF00233.19 KFR03151.1 - 1.8e-78 263.5 5.1 1.8e-78 263.5 5.1 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 KFR03151.1 - 1.8e-27 96.6 0.0 1e-12 48.8 0.0 2.5 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 KFR03151.1 - 2.1e-10 41.0 0.0 0.0003 21.1 0.0 2.4 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 KFR03151.1 - 2.3e-07 31.2 0.0 0.00063 20.1 0.0 2.8 2 1 0 2 2 2 2 GAF domain SpoVT_C PF15714.5 KFR03151.1 - 0.00016 21.7 0.1 0.035 14.1 0.0 3.3 3 0 0 3 3 3 1 Stage V sporulation protein T C-terminal, transcription factor SANT_DAMP1_like PF16282.5 KFR03151.1 - 0.095 12.9 1.2 0.52 10.5 0.1 2.7 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 DUF4316 PF14195.6 KFR03151.1 - 0.11 12.3 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) Lipocalin PF00061.23 KFR03152.1 - 4e-18 66.0 0.0 5.1e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.12 KFR03152.1 - 8.1e-10 38.8 0.0 1.2e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Lipocalin-like domain Triabin PF03973.13 KFR03152.1 - 1.3e-05 25.2 0.1 0.001 19.0 0.0 2.1 2 0 0 2 2 2 2 Triabin Glyco_hydro_39 PF01229.17 KFR03153.1 - 1.9e-147 491.8 0.0 2.3e-147 491.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 FmdA_AmdA PF03069.15 KFR03153.1 - 0.2 10.5 0.0 0.28 10.0 0.0 1.1 1 0 0 1 1 1 0 Acetamidase/Formamidase family Sulfate_transp PF00916.20 KFR03154.1 - 3.2e-123 411.3 22.7 4.3e-123 410.8 22.7 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFR03154.1 - 7.2e-26 90.1 0.0 1.4e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 STAS domain DUF3852 PF12963.7 KFR03154.1 - 1.7 9.0 7.7 0.45 10.9 0.7 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3852) Neur_chan_LBD PF02931.23 KFR03155.1 - 1.4e-76 256.7 3.5 1.8e-76 256.3 3.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFR03155.1 - 8.9e-63 212.5 8.8 1.1e-62 212.2 8.8 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF1286 PF06939.11 KFR03155.1 - 0.019 15.2 0.8 0.019 15.2 0.8 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1286) Neur_chan_LBD PF02931.23 KFR03156.1 - 2.3e-74 249.5 0.1 3.5e-74 248.9 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFR03156.1 - 2.1e-64 217.9 14.5 1.9e-49 168.9 10.0 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region PepSY_TM PF03929.16 KFR03156.1 - 0.43 10.2 5.6 0.053 13.2 1.4 1.6 2 0 0 2 2 2 0 PepSY-associated TM region THAP PF05485.12 KFR03157.1 - 5.4e-12 46.5 1.1 5.4e-12 46.5 1.1 2.0 2 1 0 2 2 2 1 THAP domain Cep57_CLD PF14073.6 KFR03157.1 - 1.7e-05 24.9 2.1 2.6e-05 24.3 2.1 1.2 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 PI3K_P85_iSH2 PF16454.5 KFR03157.1 - 0.0015 18.1 7.5 0.0021 17.7 7.5 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ADIP PF11559.8 KFR03157.1 - 0.0021 18.2 9.0 0.003 17.7 9.0 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Macoilin PF09726.9 KFR03157.1 - 0.0028 16.3 2.8 0.0038 15.9 2.8 1.1 1 0 0 1 1 1 1 Macoilin family Ax_dynein_light PF10211.9 KFR03157.1 - 0.0066 16.4 6.3 0.012 15.6 6.3 1.3 1 0 0 1 1 1 1 Axonemal dynein light chain ATG16 PF08614.11 KFR03157.1 - 0.0076 16.5 2.2 0.011 15.9 2.2 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4391 PF14335.6 KFR03157.1 - 0.014 15.1 2.4 0.022 14.5 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) GrpE PF01025.19 KFR03157.1 - 0.014 15.0 5.3 0.022 14.4 5.3 1.2 1 0 0 1 1 1 0 GrpE MPS2 PF17060.5 KFR03157.1 - 0.015 14.6 1.8 0.019 14.2 1.8 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF16 PF01519.16 KFR03157.1 - 0.018 15.5 4.2 0.033 14.7 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 Tropomyosin PF00261.20 KFR03157.1 - 0.025 14.0 6.4 0.034 13.5 6.4 1.1 1 0 0 1 1 1 0 Tropomyosin DUF573 PF04504.14 KFR03157.1 - 0.029 15.0 1.1 0.064 13.9 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF573 DUF4140 PF13600.6 KFR03157.1 - 0.076 13.5 0.6 0.12 12.9 0.6 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Sec2p PF06428.11 KFR03157.1 - 0.11 12.5 4.3 0.16 11.9 4.3 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p HGD-D PF06050.13 KFR03157.1 - 0.11 12.2 0.3 0.17 11.6 0.3 1.2 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component FlaC_arch PF05377.11 KFR03157.1 - 0.17 12.3 2.9 0.26 11.7 2.9 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 KFR03157.1 - 0.18 11.1 1.5 0.24 10.7 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 KFR03157.1 - 0.2 11.5 7.7 0.34 10.7 7.7 1.3 1 0 0 1 1 1 0 Septum formation initiator YPEB PF14620.6 KFR03157.1 - 0.24 10.7 2.9 0.32 10.3 2.9 1.1 1 0 0 1 1 1 0 YpeB sporulation FliD_C PF07195.12 KFR03157.1 - 0.37 10.2 1.4 0.51 9.7 1.4 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus ABC_tran_Xtn PF12848.7 KFR03157.1 - 0.81 9.8 9.4 1.5 8.9 9.4 1.3 1 0 0 1 1 1 0 ABC transporter Spc7 PF08317.11 KFR03157.1 - 0.96 8.3 8.1 1.4 7.8 8.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein XhlA PF10779.9 KFR03157.1 - 2.8 8.2 4.4 4.3 7.6 4.4 1.2 1 0 0 1 1 1 0 Haemolysin XhlA USP8_interact PF08941.10 KFR03157.1 - 2.8 7.7 6.1 5 6.9 6.1 1.3 1 0 0 1 1 1 0 USP8 interacting 4HBT_3 PF13622.6 KFR03157.1 - 3.8 7.7 4.5 5.1 7.3 4.5 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF1232 PF06803.12 KFR03158.1 - 2.2e-09 37.0 9.4 2.2e-09 37.0 9.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1232) zf-RING_UBOX PF13445.6 KFR03158.1 - 6e-09 35.8 5.7 1e-08 35.0 2.9 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFR03158.1 - 2.1e-08 33.9 4.1 3.5e-08 33.2 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFR03158.1 - 2.1e-08 33.9 2.8 3e-08 33.4 2.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFR03158.1 - 7.1e-08 32.5 5.0 1.7e-07 31.3 5.1 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFR03158.1 - 1.3e-06 28.6 6.7 2.1e-06 28.0 6.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFR03158.1 - 2.4e-06 27.3 5.3 5.6e-06 26.1 5.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFR03158.1 - 1.3e-05 25.0 3.9 3.4e-05 23.6 4.0 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFR03158.1 - 1.4e-05 24.9 4.7 2.9e-05 23.9 4.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Cys_rich_CPXG PF14255.6 KFR03158.1 - 0.0039 17.1 0.5 2.1 8.3 0.2 2.4 2 0 0 2 2 2 2 Cysteine-rich CPXCG zf-Nse PF11789.8 KFR03158.1 - 0.0072 16.1 1.0 0.013 15.3 1.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DpnI_C PF17726.1 KFR03158.1 - 0.023 14.8 0.1 0.04 14.1 0.1 1.4 1 0 0 1 1 1 0 Dam-replacing HTH domain zf-ANAPC11 PF12861.7 KFR03158.1 - 0.044 13.8 2.0 0.08 13.0 2.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 KFR03158.1 - 0.13 12.4 1.3 0.25 11.5 1.3 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KFR03158.1 - 0.71 10.2 5.9 1.7 9.0 5.9 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain Elf1 PF05129.13 KFR03158.1 - 1 9.4 2.7 16 5.7 2.7 2.2 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-WRNIP1_ubi PF18279.1 KFR03158.1 - 2.2 9.1 5.2 29 5.6 0.2 2.6 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain TerY_C PF15616.6 KFR03158.1 - 2.5 8.2 5.4 12 6.0 5.5 1.8 1 1 0 1 1 1 0 TerY-C metal binding domain Baculo_IE-1 PF05290.11 KFR03158.1 - 3.1 7.7 4.9 6.3 6.7 4.9 1.5 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-Di19 PF05605.12 KFR03159.1 - 3.6e-22 78.4 1.5 3.6e-22 78.4 1.5 1.9 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding ZZ PF00569.17 KFR03159.1 - 1.1e-09 37.9 6.2 1.1e-09 37.9 6.2 2.5 3 0 0 3 3 3 1 Zinc finger, ZZ type TagA PF12561.8 KFR03159.1 - 0.00091 19.6 0.2 0.0018 18.6 0.2 1.5 1 0 0 1 1 1 1 ToxR activated gene A lipoprotein domain zf-C2H2 PF00096.26 KFR03159.1 - 0.0097 16.3 0.3 0.0097 16.3 0.3 3.3 4 1 0 4 4 2 1 Zinc finger, C2H2 type Dicty_REP PF05086.12 KFR03159.1 - 0.016 13.2 4.9 0.021 12.9 4.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TFIIA PF03153.13 KFR03159.1 - 0.061 13.3 7.2 0.075 13.0 7.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zinc_ribbon_9 PF14369.6 KFR03159.1 - 0.11 12.8 1.6 12 6.3 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon FOXP-CC PF16159.5 KFR03159.1 - 0.25 12.0 3.4 36 5.1 0.4 3.4 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 KFR03159.1 - 0.34 11.3 0.1 0.34 11.3 0.1 2.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Di19_C PF14571.6 KFR03159.1 - 0.73 10.4 10.2 0.042 14.4 3.5 2.2 1 1 1 2 2 2 0 Stress-induced protein Di19, C-terminal DUF4407 PF14362.6 KFR03159.1 - 1.2 8.5 6.2 1.6 8.0 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-ribbon_3 PF13248.6 KFR03159.1 - 2.5 7.6 8.8 3.4 7.2 0.3 2.9 3 0 0 3 3 3 0 zinc-ribbon domain PPTA PF01239.22 KFR03160.1 - 7e-50 165.4 18.5 4.9e-12 45.2 0.5 6.1 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF4219 PF13961.6 KFR03160.1 - 0.11 12.2 11.4 2.9 7.7 0.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) TPR_14 PF13428.6 KFR03160.1 - 0.12 13.3 0.7 11 7.2 0.6 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat Glyco_transf_10 PF00852.19 KFR03161.1 - 4.3e-38 130.8 0.4 8e-38 129.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 KFR03161.1 - 1.4e-10 41.6 0.1 4.1e-10 40.1 0.1 1.7 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Neuregulin PF02158.15 KFR03162.1 - 6.7e-150 499.4 34.6 9e-150 499.0 34.6 1.2 1 0 0 1 1 1 1 Neuregulin intracellular region I-set PF07679.16 KFR03162.1 - 9.7e-15 54.4 0.8 5.5e-14 52.0 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR03162.1 - 1.7e-11 44.6 0.0 1.7e-11 44.6 0.0 2.6 3 0 0 3 3 2 1 Immunoglobulin domain ig PF00047.25 KFR03162.1 - 3.5e-10 39.9 1.5 7.2e-10 38.9 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFR03162.1 - 5.4e-09 36.3 0.3 2.6e-08 34.1 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFR03162.1 - 2.8e-06 27.4 0.4 3.2e-05 24.1 0.1 2.8 2 1 0 2 2 2 1 Immunoglobulin V-set domain C1-set PF07654.15 KFR03162.1 - 0.0002 21.7 1.0 0.00074 19.8 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin C1-set domain C2-set_2 PF08205.12 KFR03162.1 - 0.001 19.1 1.3 0.012 15.6 0.0 2.8 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain EGF PF00008.27 KFR03162.1 - 0.0016 18.7 3.8 0.0032 17.7 3.8 1.5 1 0 0 1 1 1 1 EGF-like domain DUF973 PF06157.11 KFR03162.1 - 0.034 13.2 0.0 0.064 12.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF973) Cyt_b-c1_8 PF10890.8 KFR03162.1 - 0.08 13.4 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 TMEM132D_C PF15706.5 KFR03162.1 - 0.13 12.1 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term EGF_2 PF07974.13 KFR03162.1 - 0.6 10.5 2.6 1.8 9.0 2.6 1.8 1 1 0 1 1 1 0 EGF-like domain V-set PF07686.17 KFR03180.1 - 2.6e-07 30.8 0.1 2.6e-07 30.8 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFR03180.1 - 0.069 13.8 0.1 0.076 13.6 0.1 1.1 1 0 0 1 1 1 0 Immunoglobulin domain Pkinase PF00069.25 KFR03181.1 - 4.5e-25 88.5 0.0 5e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR03181.1 - 8e-11 41.7 0.0 9.2e-11 41.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase DNA_pol_B_palm PF14792.6 KFR03195.1 - 2.5e-39 134.0 0.1 5.6e-39 132.9 0.1 1.6 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 KFR03195.1 - 1.2e-21 76.2 0.0 2.6e-20 72.0 0.0 2.5 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 KFR03195.1 - 2.9e-17 62.6 0.0 6.6e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 KFR03195.1 - 1.6e-11 44.4 0.5 1.4e-09 38.1 0.2 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.6 KFR03195.1 - 5.2e-09 36.6 0.1 9.7e-06 26.1 0.0 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 KFR03195.1 - 9.2e-05 22.7 0.1 0.00022 21.5 0.1 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH_2 PF12826.7 KFR03195.1 - 0.0018 18.3 0.0 0.57 10.3 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_3 PF12836.7 KFR03195.1 - 0.0034 17.6 0.2 2.4 8.5 0.0 3.8 4 1 0 4 4 4 1 Helix-hairpin-helix motif HHH PF00633.23 KFR03195.1 - 0.0078 16.0 0.2 4.8 7.2 0.2 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif Cdd1 PF11731.8 KFR03195.1 - 0.0084 16.3 0.0 0.062 13.6 0.0 2.3 2 1 0 2 2 2 1 Pathogenicity locus WSN PF02206.18 KFR03195.1 - 0.02 14.8 0.1 9 6.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF3701 PF12482.8 KFR03195.1 - 0.16 12.1 0.0 18 5.5 0.0 2.4 2 0 0 2 2 2 0 Phage integrase protein Ant_C PF05586.11 KFR03196.1 - 5.2e-43 145.6 1.0 6.4e-43 145.3 1.0 1.1 1 0 0 1 1 1 1 Anthrax receptor C-terminus region SIS PF01380.22 KFR03197.1 - 4e-69 230.5 0.1 1.9e-36 124.8 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KFR03197.1 - 1.7e-16 60.6 0.0 4.7e-16 59.2 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KFR03197.1 - 2.1e-12 47.1 0.0 4.9e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KFR03197.1 - 0.00021 20.3 0.0 0.00035 19.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 KFR03197.1 - 0.00059 18.7 0.0 0.001 17.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 KFR03197.1 - 0.021 14.8 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 SIS domain Nfu_N PF08712.11 KFR03198.1 - 3.3e-34 116.8 0.0 5.8e-34 116.0 0.0 1.4 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KFR03198.1 - 8.4e-26 89.9 0.1 1.2e-25 89.5 0.1 1.2 1 0 0 1 1 1 1 NifU-like domain BMP2K_C PF15282.6 KFR03199.1 - 2.4e-33 116.1 18.5 2.5e-27 96.4 6.6 3.2 2 2 1 3 3 3 3 BMP-2-inducible protein kinase C-terminus BMP2K_C PF15282.6 KFR03200.1 - 0.0065 16.4 0.1 0.0072 16.2 0.1 1.1 1 0 0 1 1 1 1 BMP-2-inducible protein kinase C-terminus Pkinase PF00069.25 KFR03201.1 - 3.1e-42 144.8 0.0 3.1e-42 144.8 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR03201.1 - 6.8e-25 87.8 0.0 6.8e-25 87.8 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFR03201.1 - 0.023 13.5 0.0 0.023 13.5 0.0 2.7 2 1 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 KFR03201.1 - 0.035 13.0 0.1 0.035 13.0 0.1 2.3 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 KFR03201.1 - 0.051 13.5 0.2 0.051 13.5 0.2 3.4 2 2 1 4 4 4 0 Phosphotransferase enzyme family Annexin PF00191.20 KFR03202.1 - 1.2e-34 118.2 0.6 4e-26 90.9 0.1 2.0 2 0 0 2 2 2 2 Annexin BTB PF00651.31 KFR03203.1 - 2e-14 53.8 0.0 1.2e-13 51.3 0.0 2.2 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFR03203.1 - 1e-06 28.8 0.2 3.2e-06 27.2 0.2 1.9 1 0 0 1 1 1 1 BTB And C-terminal Kelch TGF_beta PF00019.20 KFR03204.1 - 3.3e-12 47.3 0.5 5.3e-12 46.6 0.5 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain zf-HC5HC2H PF13771.6 KFR03212.1 - 7.4e-08 32.5 1.5 7.4e-08 32.5 1.5 3.4 3 1 0 3 3 3 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFR03212.1 - 0.00072 19.7 1.4 0.00072 19.7 1.4 3.3 2 1 1 3 3 3 2 PHD-zinc-finger like domain OrfB_Zn_ribbon PF07282.11 KFR03212.1 - 0.015 15.2 0.8 0.015 15.2 0.8 3.5 2 2 2 4 4 4 0 Putative transposase DNA-binding domain Trm112p PF03966.16 KFR03212.1 - 0.1 13.2 1.2 1.2 9.8 0.1 2.5 2 0 0 2 2 2 0 Trm112p-like protein zinc_ribbon_4 PF13717.6 KFR03212.1 - 0.11 12.4 7.3 0.71 9.8 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 KFR03212.1 - 2 8.5 11.2 1.1 9.3 0.2 3.6 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-RING_2 PF13639.6 KFR03213.1 - 1.3e-05 25.5 8.9 2.2e-05 24.7 8.9 1.4 1 0 0 1 1 1 1 Ring finger domain zinc_ribbon_4 PF13717.6 KFR03213.1 - 0.00013 21.8 0.5 0.1 12.6 0.0 2.3 2 0 0 2 2 2 2 zinc-ribbon domain zf-RING_4 PF14570.6 KFR03213.1 - 0.00033 20.4 8.0 0.046 13.5 0.8 2.7 3 0 0 3 3 3 2 RING/Ubox like zinc-binding domain OrfB_Zn_ribbon PF07282.11 KFR03213.1 - 0.00071 19.5 5.2 0.0033 17.3 0.8 2.1 1 1 1 2 2 2 1 Putative transposase DNA-binding domain zf-RING_11 PF17123.5 KFR03213.1 - 0.015 15.1 3.7 0.015 15.1 3.7 1.9 2 0 0 2 2 1 0 RING-like zinc finger zf-NADH-PPase PF09297.11 KFR03213.1 - 0.029 14.0 5.9 0.67 9.7 0.1 2.7 2 1 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain PhnA_Zn_Ribbon PF08274.12 KFR03213.1 - 0.039 13.9 7.6 0.31 11.0 0.1 2.5 3 0 0 3 3 2 0 PhnA Zinc-Ribbon zf-3CxxC_2 PF17180.4 KFR03213.1 - 0.046 14.5 5.3 1.1 10.1 0.6 2.5 2 0 0 2 2 2 0 Zinc-binding domain Trm112p PF03966.16 KFR03213.1 - 0.049 14.2 0.9 0.37 11.4 0.1 2.1 2 0 0 2 2 2 0 Trm112p-like protein TF_Zn_Ribbon PF08271.12 KFR03213.1 - 0.11 12.0 4.8 4.4 6.9 1.4 2.4 2 1 0 2 2 2 0 TFIIB zinc-binding zinc-ribbons_6 PF07191.12 KFR03213.1 - 0.12 12.4 5.5 0.21 11.6 2.9 2.1 1 1 1 2 2 2 0 zinc-ribbons zf-RING_5 PF14634.6 KFR03213.1 - 0.15 12.0 11.9 0.3 11.1 10.5 2.0 1 1 1 2 2 2 0 zinc-RING finger domain CpXC PF14353.6 KFR03213.1 - 0.22 11.6 3.1 0.75 9.8 0.2 2.3 1 1 1 2 2 2 0 CpXC protein zf-TFIIB PF13453.6 KFR03213.1 - 0.23 10.8 4.4 3.2 7.2 4.9 2.1 1 1 2 3 3 3 0 Transcription factor zinc-finger zinc_ribbon_9 PF14369.6 KFR03213.1 - 0.3 11.4 10.3 2.9 8.2 0.3 3.2 2 1 0 2 2 2 0 zinc-ribbon zinc_ribbon_10 PF10058.9 KFR03213.1 - 0.34 10.7 9.5 1.1 9.0 9.5 1.9 1 1 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein PknG_rubred PF16919.5 KFR03213.1 - 0.35 11.0 4.0 18 5.5 4.0 2.1 1 1 0 1 1 1 0 Protein kinase G rubredoxin domain Zn_Tnp_IS1595 PF12760.7 KFR03213.1 - 0.35 10.9 11.3 2 8.5 8.3 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Anti-TRAP PF15777.5 KFR03213.1 - 0.61 10.1 4.8 2 8.4 0.9 2.2 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-Di19 PF05605.12 KFR03213.1 - 0.69 10.2 0.2 0.69 10.2 0.2 2.8 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-UDP PF14569.6 KFR03213.1 - 0.77 9.9 6.0 9.1 6.5 6.0 2.6 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-AN1 PF01428.16 KFR03213.1 - 0.92 9.7 9.2 0.76 10.0 0.7 3.2 3 1 0 3 3 3 0 AN1-like Zinc finger TFIIS_C PF01096.18 KFR03213.1 - 1.1 9.2 7.2 9.6 6.2 0.1 2.9 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) zf-FPG_IleRS PF06827.14 KFR03213.1 - 2 8.4 9.9 1.6 8.7 0.3 3.1 3 1 0 3 3 3 0 Zinc finger found in FPG and IleRS IBR PF01485.21 KFR03213.1 - 2.2 8.5 11.6 0.25 11.6 1.8 2.7 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain DUF1451 PF07295.11 KFR03213.1 - 2.7 8.0 5.4 4.1 7.4 1.4 2.1 1 1 1 2 2 2 0 Zinc-ribbon containing domain Thioredoxin_4 PF13462.6 KFR03213.1 - 2.7 8.1 5.5 1.2 9.3 0.9 2.0 1 1 1 2 2 2 0 Thioredoxin IL8 PF00048.20 KFR03222.1 - 9.2e-19 67.4 0.2 1e-18 67.2 0.2 1.0 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Ig_2 PF13895.6 KFR03223.1 - 0.00011 22.4 0.1 0.001 19.4 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 KFR03223.1 - 0.0002 21.9 0.6 0.00088 19.8 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain IL12p40_C PF10420.9 KFR03223.1 - 0.0018 18.8 0.0 0.004 17.6 0.0 1.5 1 0 0 1 1 1 1 Cytokine interleukin-12p40 C-terminus ig PF00047.25 KFR03223.1 - 0.0073 16.5 0.1 0.07 13.3 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain ISK_Channel PF02060.15 KFR03223.1 - 0.021 14.5 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Slow voltage-gated potassium channel EpoR_lig-bind PF09067.10 KFR03223.1 - 0.022 15.0 0.1 0.042 14.0 0.1 1.4 1 0 0 1 1 1 0 Erythropoietin receptor, ligand binding TMEM154 PF15102.6 KFR03223.1 - 0.028 14.3 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF2207 PF09972.9 KFR03223.1 - 0.068 11.9 0.0 0.098 11.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Stevor PF17410.2 KFR03223.1 - 0.29 10.7 0.0 0.43 10.1 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame fn3 PF00041.21 KFR03224.1 - 2.4e-07 31.0 1.7 7.7e-07 29.4 0.2 2.5 2 1 0 2 2 2 1 Fibronectin type III domain Ig_5 PF16681.5 KFR03224.1 - 7.9e-06 26.2 0.1 1.8e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_2 PF13895.6 KFR03224.1 - 4.6e-05 23.7 0.2 0.00014 22.2 0.2 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFR03224.1 - 0.00013 22.5 0.2 0.00013 22.5 0.2 2.8 3 1 0 3 3 3 1 Immunoglobulin domain Ig_4 PF16680.5 KFR03224.1 - 0.0013 19.0 0.1 0.0025 18.0 0.1 1.5 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 delta chain I-set PF07679.16 KFR03224.1 - 0.01 15.9 0.4 0.14 12.3 0.1 2.7 2 0 0 2 2 2 0 Immunoglobulin I-set domain ig PF00047.25 KFR03224.1 - 0.034 14.3 0.2 0.47 10.7 0.1 2.5 2 0 0 2 2 2 0 Immunoglobulin domain IL12p40_C PF10420.9 KFR03224.1 - 0.048 14.2 0.1 0.17 12.4 0.1 2.0 2 0 0 2 2 2 0 Cytokine interleukin-12p40 C-terminus GalP_UDP_tr_C PF02744.17 KFR03225.1 - 5.1e-53 179.2 0.0 7.7e-53 178.6 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.22 KFR03225.1 - 5e-42 144.4 0.0 7.6e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain HIT PF01230.23 KFR03225.1 - 0.0041 17.8 0.0 0.039 14.7 0.0 2.1 2 0 0 2 2 2 1 HIT domain ERG2_Sigma1R PF04622.12 KFR03226.1 - 3.8e-64 215.9 0.4 4.4e-64 215.7 0.4 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein ARID PF01388.21 KFR03227.1 - 4.2e-20 72.2 0.0 7.8e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain ketoacyl-synt PF00109.26 KFR03227.1 - 0.024 14.2 0.2 0.041 13.4 0.2 1.3 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Dynactin_p22 PF07426.11 KFR03229.1 - 2.6e-38 131.5 2.8 3.1e-38 131.3 2.8 1.1 1 0 0 1 1 1 1 Dynactin subunit p22 Alba PF01918.21 KFR03230.1 - 2.5e-16 59.2 0.8 3.4e-16 58.8 0.8 1.2 1 0 0 1 1 1 1 Alba Hit1_C PF18268.1 KFR03230.1 - 0.18 11.9 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Hit1 C-terminal EF-hand_7 PF13499.6 KFR03266.1 - 2.4e-26 92.0 1.8 5.4e-19 68.4 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFR03266.1 - 1.1e-22 77.8 10.7 2.4e-08 32.9 0.2 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFR03266.1 - 6.1e-20 69.4 6.2 4.1e-06 26.3 0.1 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KFR03266.1 - 4.5e-18 63.9 3.7 6.9e-06 25.3 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KFR03266.1 - 6.5e-15 54.7 7.5 2.7e-06 27.1 0.2 3.4 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFR03266.1 - 7e-09 36.0 2.1 7.6e-06 26.2 0.5 3.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFR03266.1 - 8e-05 22.5 2.7 0.0062 16.5 0.1 2.9 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFR03266.1 - 0.00036 20.8 0.2 4.2 7.8 0.1 3.4 3 1 0 3 3 3 2 EF-hand domain Dockerin_1 PF00404.18 KFR03266.1 - 0.0014 18.8 0.9 0.13 12.5 0.1 2.4 1 1 1 2 2 2 2 Dockerin type I domain Caleosin PF05042.13 KFR03266.1 - 0.025 14.5 7.5 2.4 8.1 0.1 3.4 2 1 1 3 3 3 0 Caleosin related protein S10_plectin PF03501.15 KFR03266.1 - 0.066 13.3 0.1 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 Plectin/S10 domain EF-hand_2 PF09068.11 KFR03266.1 - 0.069 13.3 0.1 15 5.8 0.0 2.8 2 1 0 2 2 2 0 EF hand ParcG PF10274.9 KFR03267.1 - 1.8e-48 165.1 0.0 2.3e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein HEAT_EZ PF13513.6 KFR03267.1 - 0.1 13.2 0.7 0.93 10.1 0.1 2.2 1 1 1 2 2 2 0 HEAT-like repeat LRR_8 PF13855.6 KFR03268.1 - 4.3e-90 295.4 84.3 1.3e-13 50.5 0.0 10.2 4 4 6 10 10 10 10 Leucine rich repeat LRR_5 PF13306.6 KFR03268.1 - 9.1e-33 112.9 9.7 4.3e-09 36.4 0.1 5.1 6 0 0 6 6 4 4 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFR03268.1 - 1.3e-31 108.1 63.1 3.3e-05 24.2 0.1 12.1 7 5 8 16 16 16 11 Leucine Rich repeats (2 copies) EGF PF00008.27 KFR03268.1 - 7.2e-27 93.3 94.7 4.1e-08 33.4 7.7 8.5 9 0 0 9 9 8 5 EGF-like domain LRR_9 PF14580.6 KFR03268.1 - 1.1e-21 77.1 16.8 6.1e-07 29.1 0.5 4.6 4 1 0 4 4 4 4 Leucine-rich repeat LRRNT PF01462.18 KFR03268.1 - 2.6e-21 74.8 36.9 1.7e-08 33.9 3.3 7.0 6 0 0 6 6 6 3 Leucine rich repeat N-terminal domain Laminin_G_1 PF00054.23 KFR03268.1 - 6.3e-18 65.2 0.0 1.1e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain LRRCT PF01463.24 KFR03268.1 - 1.7e-17 62.4 8.1 0.0026 18.2 0.1 6.1 6 0 0 6 6 5 4 Leucine rich repeat C-terminal domain Laminin_G_2 PF02210.24 KFR03268.1 - 3.3e-15 56.8 0.0 6.8e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain hEGF PF12661.7 KFR03268.1 - 3.9e-12 46.3 84.1 1.1e-06 29.0 5.7 9.9 10 1 0 10 10 8 5 Human growth factor-like EGF LRR_1 PF00560.33 KFR03268.1 - 1.4e-05 25.0 44.9 2.5 9.0 0.6 14.4 16 2 0 16 16 16 3 Leucine Rich Repeat FXa_inhibition PF14670.6 KFR03268.1 - 0.0007 19.8 4.2 0.0007 19.8 4.2 7.2 4 2 2 6 6 5 3 Coagulation Factor Xa inhibitory site TPKR_C2 PF16920.5 KFR03268.1 - 2.8 8.1 19.4 7.7 6.7 0.5 6.6 6 0 0 6 6 5 0 Tyrosine-protein kinase receptor C2 Ig-like domain HTH_psq PF05225.16 KFR03269.1 - 1.5e-24 85.4 0.0 5e-16 58.2 0.0 2.5 2 0 0 2 2 2 2 helix-turn-helix, Psq domain DUF2428 PF10350.9 KFR03269.1 - 0.012 14.9 0.8 0.51 9.6 0.0 2.6 2 0 0 2 2 2 0 Putative death-receptor fusion protein (DUF2428) DUF4553 PF15090.6 KFR03271.1 - 1.1e-157 525.9 30.2 1.1e-157 525.9 30.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4553) Staphostatin_A PF09022.10 KFR03271.1 - 0.038 13.9 0.1 0.086 12.8 0.1 1.5 1 0 0 1 1 1 0 Staphostatin A Cnd3 PF12719.7 KFR03272.1 - 3.4e-85 285.8 2.2 3.4e-85 285.8 2.2 3.0 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KFR03272.1 - 1e-09 38.6 6.0 0.003 17.9 0.4 5.2 5 0 0 5 5 5 3 HEAT repeats HEAT PF02985.22 KFR03272.1 - 1.1e-07 31.4 7.3 1.1 9.7 0.0 7.9 9 0 0 9 9 9 2 HEAT repeat HEAT_EZ PF13513.6 KFR03272.1 - 0.00053 20.4 5.9 5.2 7.7 0.2 4.9 3 1 1 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 KFR03272.1 - 0.0024 18.0 13.3 0.47 10.5 0.3 5.5 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 UVR PF02151.19 KFR03272.1 - 0.074 12.8 1.8 0.3 10.9 0.4 2.6 2 0 0 2 2 2 0 UvrB/uvrC motif RVT_1 PF00078.27 KFR03273.1 - 0.0023 17.5 0.0 0.0049 16.4 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Med28 PF11594.8 KFR03274.1 - 1e-24 87.1 1.6 3.5e-18 66.0 0.7 2.0 1 1 1 2 2 2 2 Mediator complex subunit 28 Filament PF00038.21 KFR03274.1 - 0.00082 19.0 1.2 0.00089 18.9 1.2 1.1 1 0 0 1 1 1 1 Intermediate filament protein HTH_34 PF13601.6 KFR03274.1 - 0.0069 16.5 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HU-CCDC81_bac_2 PF18175.1 KFR03274.1 - 0.01 15.7 0.3 0.019 14.8 0.3 1.5 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 Sec2p PF06428.11 KFR03274.1 - 0.18 11.8 3.5 0.26 11.3 3.5 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Peptidase_M17 PF00883.21 KFR03275.1 - 3.7e-121 404.2 0.0 4.9e-121 403.8 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 KFR03275.1 - 6.7e-20 71.2 0.1 1.5e-19 70.1 0.1 1.6 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain PMP22_Claudin PF00822.20 KFR03276.1 - 0.0058 16.5 1.9 0.0088 15.9 1.9 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.11 KFR03276.1 - 0.034 14.1 13.1 0.28 11.1 13.1 2.3 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Claudin_2 PF13903.6 KFR03276.1 - 1.5 8.5 0.0 1.5 8.5 0.0 2.4 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction adh_short_C2 PF13561.6 KFR03277.1 - 0.069 12.7 0.0 0.069 12.7 0.0 1.0 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase HTH_IclR PF09339.10 KFR03277.1 - 0.13 12.0 0.0 0.31 10.9 0.0 1.6 1 1 1 2 2 2 0 IclR helix-turn-helix domain GoLoco PF02188.17 KFR03313.1 - 7.9e-39 130.7 28.9 2.1e-10 39.9 3.6 4.5 4 0 0 4 4 4 4 GoLoco motif TPR_12 PF13424.6 KFR03313.1 - 1.2e-38 131.2 30.5 1e-11 45.0 5.8 5.6 4 2 1 6 6 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 KFR03313.1 - 1.1e-35 119.9 32.6 9.7e-07 28.4 0.4 8.2 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_7 PF13176.6 KFR03313.1 - 6.1e-32 107.3 23.5 2.6e-06 27.1 0.4 8.7 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 KFR03313.1 - 8e-21 72.5 19.1 0.00031 20.7 0.3 7.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KFR03313.1 - 2.5e-20 70.9 29.3 0.00032 20.6 0.6 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_10 PF13374.6 KFR03313.1 - 2e-18 65.6 27.5 0.00038 20.2 0.4 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_4 PF07721.14 KFR03313.1 - 2.8e-08 33.6 0.1 0.46 11.3 0.2 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFR03313.1 - 4e-06 26.5 7.0 0.005 16.3 4.3 2.9 2 1 0 2 2 2 2 MalT-like TPR region Rapsyn_N PF10579.9 KFR03313.1 - 1.1e-05 25.4 2.4 8.3 6.6 0.1 5.9 4 2 2 6 6 6 1 Rapsyn N-terminal myristoylation and linker region TPR_14 PF13428.6 KFR03313.1 - 2.8e-05 24.6 8.6 3.6 8.7 0.1 6.4 6 1 1 7 7 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFR03313.1 - 5.2e-05 23.8 15.0 0.024 15.3 0.8 6.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFR03313.1 - 0.0002 21.0 21.9 0.26 11.0 0.2 7.5 6 2 1 7 7 7 2 TPR repeat TPR_6 PF13174.6 KFR03313.1 - 0.015 15.9 6.5 20 6.1 0.2 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFR03313.1 - 0.016 15.5 15.9 22 5.7 0.1 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFR03313.1 - 0.068 13.4 13.7 3.8 7.8 2.9 5.2 3 1 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 KFR03313.1 - 0.16 11.7 1.8 1.5 8.5 0.3 3.1 2 2 0 2 2 2 0 26S proteasome subunit RPN7 Sec1 PF00995.23 KFR03314.1 - 6.6e-124 415.2 5.5 7.5e-124 415.1 5.5 1.0 1 0 0 1 1 1 1 Sec1 family PDZ_3 PF17815.1 KFR03314.1 - 0.053 13.4 0.2 0.14 12.0 0.2 1.7 1 0 0 1 1 1 0 PDZ domain ApoLp-III PF07464.11 KFR03314.1 - 0.28 11.3 2.1 0.27 11.3 0.2 1.9 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) MazG PF03819.17 KFR03314.1 - 1.4 9.2 3.6 0.94 9.7 0.9 2.1 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain PRP38 PF03371.15 KFR03315.1 - 8.4e-58 195.1 0.0 1.2e-57 194.6 0.0 1.2 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 KFR03315.1 - 0.0017 18.9 42.3 0.0017 18.9 42.3 3.6 1 1 3 4 4 4 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Methyltransf_12 PF08242.12 KFR03316.1 - 0.0043 17.8 0.0 0.0087 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFR03316.1 - 0.13 13.0 0.0 0.3 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain NT-C2 PF10358.9 KFR03317.1 - 1.5e-15 57.2 0.0 2.6e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Mito_carr PF00153.27 KFR03318.1 - 7e-74 243.9 5.1 4.1e-26 90.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KFR03318.1 - 1.9e-21 73.9 6.6 4.2e-06 25.9 0.7 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFR03318.1 - 5.3e-21 74.9 2.3 3e-10 40.4 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFR03318.1 - 6.7e-20 69.3 6.8 0.0003 20.5 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFR03318.1 - 4.8e-18 63.8 6.3 2.5e-05 23.6 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KFR03318.1 - 7.2e-12 45.0 4.8 1.4e-08 34.5 0.3 4.1 2 2 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFR03318.1 - 6e-08 33.0 0.1 0.016 15.5 0.1 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KFR03318.1 - 2e-06 27.5 0.8 0.0033 17.2 0.0 3.8 2 2 2 4 4 4 1 EF hand Dockerin_1 PF00404.18 KFR03318.1 - 0.00012 22.2 0.3 0.15 12.2 0.1 3.2 3 0 0 3 3 3 1 Dockerin type I domain EF-hand_9 PF14658.6 KFR03318.1 - 0.00019 21.7 0.0 1.3 9.4 0.0 3.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KFR03318.1 - 0.00027 20.8 3.0 0.0085 16.0 0.1 2.9 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand DUF2340 PF10209.9 KFR03318.1 - 0.0097 16.4 0.0 0.037 14.5 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2340) B5 PF03484.15 KFR03318.1 - 0.024 14.9 0.0 0.086 13.2 0.0 2.0 1 0 0 1 1 1 0 tRNA synthetase B5 domain Sigma_reg_C PF13791.6 KFR03318.1 - 0.026 14.7 0.2 0.086 13.1 0.3 1.8 2 0 0 2 2 2 0 Sigma factor regulator C-terminal RhoGEF PF00621.20 KFR03319.1 - 9.2e-39 133.6 8.0 9.2e-39 133.6 8.0 1.8 2 0 0 2 2 2 1 RhoGEF domain SH3_2 PF07653.17 KFR03319.1 - 4.4e-24 83.9 0.0 3.8e-14 52.1 0.0 2.9 3 0 0 3 3 2 2 Variant SH3 domain SH3_9 PF14604.6 KFR03319.1 - 3.8e-18 65.1 0.1 2.1e-11 43.5 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KFR03319.1 - 1.8e-17 62.6 0.1 1.2e-13 50.4 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH2 PF00017.24 KFR03319.1 - 1.7e-15 56.9 0.5 8.6e-15 54.6 0.5 2.3 1 0 0 1 1 1 1 SH2 domain C1_1 PF00130.22 KFR03319.1 - 2e-09 37.2 4.9 3.8e-09 36.3 4.9 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 KFR03319.1 - 8.8e-08 32.6 0.1 2.2e-07 31.3 0.1 1.7 1 0 0 1 1 1 1 PH domain CH PF00307.31 KFR03319.1 - 2e-06 27.9 0.1 1.3e-05 25.3 0.0 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain Filamin PF00630.19 KFR03319.1 - 0.00037 21.3 0.0 0.0019 19.0 0.1 2.2 1 1 0 1 1 1 1 Filamin/ABP280 repeat Prok-RING_1 PF14446.6 KFR03319.1 - 0.0035 17.2 1.3 0.0086 16.0 1.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 C1_2 PF03107.16 KFR03319.1 - 0.0062 16.8 3.6 0.015 15.6 3.6 1.7 1 0 0 1 1 1 1 C1 domain LZ3wCH PF18517.1 KFR03319.1 - 0.011 15.8 2.3 0.014 15.5 0.1 2.4 2 0 0 2 2 1 0 Leucine zipper with capping helix domain CAMSAP_CH PF11971.8 KFR03319.1 - 0.013 15.3 1.6 0.033 14.0 0.1 2.5 2 0 0 2 2 2 0 CAMSAP CH domain DUF2326 PF10088.9 KFR03319.1 - 0.024 14.4 0.2 5.2 6.8 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2326) PH_10 PF15411.6 KFR03319.1 - 0.089 13.1 2.3 0.15 12.3 0.1 2.5 3 0 0 3 3 3 0 Pleckstrin homology domain Zn_ribbon_17 PF17120.5 KFR03319.1 - 0.19 11.4 2.9 0.51 10.0 2.9 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Zf_RING PF16744.5 KFR03319.1 - 5.9 7.1 7.4 0.32 11.1 0.8 2.3 3 0 0 3 3 2 0 KIAA1045 RING finger Laminin_N PF00055.17 KFR03320.1 - 1.9e-55 188.0 0.0 1.9e-55 188.0 0.0 2.9 3 1 1 4 4 4 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 KFR03320.1 - 2.1e-22 79.0 63.8 2.1e-08 34.2 11.6 4.8 3 1 1 4 4 4 3 Laminin EGF domain EGF_2 PF07974.13 KFR03320.1 - 0.0022 18.3 10.1 0.0022 18.3 10.1 7.4 6 2 0 6 6 6 1 EGF-like domain hEGF PF12661.7 KFR03320.1 - 0.0042 17.7 8.2 0.0042 17.7 8.2 7.1 7 1 1 8 8 8 1 Human growth factor-like EGF EGF PF00008.27 KFR03320.1 - 0.0061 16.8 9.1 0.0061 16.8 9.1 6.3 5 2 0 5 5 5 1 EGF-like domain Alpha-amylase_C PF02806.18 KFR03321.1 - 2.5e-14 53.5 0.2 6.1e-14 52.3 0.2 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 KFR03321.1 - 9.7e-14 51.7 0.0 1.8e-13 50.8 0.0 1.3 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Ribosomal_S13 PF00416.22 KFR03322.1 - 0.018 15.4 0.1 0.02 15.3 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein S13/S18 Bromodomain PF00439.25 KFR03323.1 - 1.9e-14 53.5 0.4 3e-14 52.8 0.4 1.3 1 0 0 1 1 1 1 Bromodomain COLFI PF01410.18 KFR03324.1 - 4.4e-84 281.4 0.0 5.6e-84 281.1 0.0 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain 7tm_1 PF00001.21 KFR03333.1 - 2.2e-33 115.7 26.7 1.2e-31 110.0 26.7 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR03333.1 - 9.6e-11 41.5 18.0 1.3e-08 34.5 18.0 2.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFR03333.1 - 1.1e-07 31.8 20.2 1.6e-07 31.4 12.2 2.2 1 1 1 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFR03333.1 - 4.8e-06 26.4 14.1 4.8e-06 26.4 14.1 2.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 KFR03334.1 - 1.7e-37 129.2 38.4 7.3e-36 123.8 38.4 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFR03334.1 - 3.7e-13 49.9 28.9 3.4e-11 43.4 23.9 2.9 1 1 1 2 2 2 2 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KFR03334.1 - 6.4e-10 38.8 39.5 9.1e-10 38.3 39.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFR03334.1 - 0.15 11.7 42.4 0.72 9.4 39.4 2.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Pox_MCEL PF03291.16 KFR03335.1 - 4.4e-110 367.9 2.2 5.5e-110 367.6 2.2 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 KFR03335.1 - 6.1e-12 46.1 0.0 1.3e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFR03335.1 - 2.7e-11 43.5 0.1 4.6e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFR03335.1 - 1.9e-08 34.9 0.0 4.3e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFR03335.1 - 9.3e-07 28.8 0.0 2.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFR03335.1 - 2.5e-06 28.1 0.0 4.9e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KFR03335.1 - 0.0026 17.7 0.0 0.0072 16.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KFR03335.1 - 0.013 15.3 0.1 0.025 14.4 0.1 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase NNMT_PNMT_TEMT PF01234.17 KFR03335.1 - 0.025 13.8 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family MTS PF05175.14 KFR03335.1 - 0.026 14.1 0.0 0.065 12.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain DUF1279 PF06916.13 KFR03336.1 - 7.2e-24 84.2 0.4 7.2e-24 84.2 0.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1279) Apolipoprotein PF01442.18 KFR03336.1 - 1.5e-05 25.0 0.5 2.2e-05 24.4 0.5 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain LEA_4 PF02987.16 KFR03336.1 - 5.4e-05 23.2 11.5 5.4e-05 23.2 11.5 1.7 1 1 0 1 1 1 1 Late embryogenesis abundant protein YtxH PF12732.7 KFR03336.1 - 0.00011 22.6 9.3 0.00024 21.6 9.3 1.5 1 0 0 1 1 1 1 YtxH-like protein DctP PF03480.13 KFR03336.1 - 0.025 13.9 0.4 0.036 13.4 0.4 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 Mit_KHE1 PF10173.9 KFR03336.1 - 0.033 14.3 1.0 0.05 13.7 1.0 1.3 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF3810 PF12725.7 KFR03336.1 - 0.044 13.1 0.1 0.052 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Herpes_UL36 PF03586.13 KFR03336.1 - 0.066 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein DUF883 PF05957.13 KFR03336.1 - 0.086 13.5 1.1 0.16 12.6 1.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) FUN14 PF04930.15 KFR03336.1 - 0.092 13.2 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 FUN14 family HTH_39 PF14090.6 KFR03336.1 - 0.1 12.4 0.0 0.29 10.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Phasin PF05597.11 KFR03336.1 - 0.45 10.5 3.7 0.76 9.8 3.7 1.2 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1664 PF07889.12 KFR03336.1 - 1.2 9.2 5.0 2.2 8.3 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Mt_ATP-synt_D PF05873.12 KFR03336.1 - 1.2 9.0 9.7 19 5.1 8.2 2.3 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Phe_tRNA-synt_N PF02912.18 KFR03336.1 - 1.5 8.8 5.4 4.7 7.2 5.1 2.0 2 1 0 2 2 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain m04gp34like PF12216.8 KFR03337.1 - 0.1 12.2 0.9 0.22 11.1 0.6 1.6 2 0 0 2 2 2 0 Immune evasion protein Shisa PF13908.6 KFR03337.1 - 0.11 12.8 0.2 0.11 12.8 0.2 1.9 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF4834 PF16118.5 KFR03337.1 - 0.14 13.1 1.7 0.26 12.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TMEM154 PF15102.6 KFR03337.1 - 0.18 11.7 0.7 0.37 10.7 0.7 1.5 1 0 0 1 1 1 0 TMEM154 protein family PspB PF06667.12 KFR03337.1 - 0.21 11.7 0.3 0.33 11.0 0.3 1.3 1 0 0 1 1 1 0 Phage shock protein B ASH PF15780.5 KFR03338.1 - 3.2e-18 65.8 6.1 0.00038 20.6 0.1 7.7 7 1 0 7 7 7 5 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 KFR03338.1 - 3e-13 49.8 3.0 0.034 14.4 0.0 6.9 7 1 0 7 7 7 4 Transmembrane protein 131-like Motile_Sperm PF00635.26 KFR03338.1 - 1.2e-09 38.0 3.0 0.025 14.4 0.0 5.8 6 0 0 6 6 6 2 MSP (Major sperm protein) domain MYCBPAP PF14646.6 KFR03338.1 - 1.2e-07 31.0 0.1 0.00091 18.3 0.0 4.0 4 0 0 4 4 4 2 MYCBP-associated protein family DUF1573 PF07610.11 KFR03338.1 - 0.011 15.8 1.8 4.1 7.5 0.0 4.6 5 1 0 5 5 5 0 Protein of unknown function (DUF1573) DUF5061 PF16587.5 KFR03339.1 - 0.11 12.6 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 17 kDa common-antigen outer membrane protein WD40 PF00400.32 KFR03341.1 - 4.7e-10 39.9 23.7 0.00017 22.3 1.9 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR03341.1 - 8.1e-07 29.3 1.8 0.021 15.1 0.3 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFR03341.1 - 0.00023 20.2 0.1 0.24 10.3 0.0 2.8 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Y_phosphatase PF00102.27 KFR03342.1 - 4.8e-77 258.7 0.1 5.4e-77 258.5 0.1 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFR03342.1 - 0.0058 16.4 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFR03342.1 - 0.018 15.0 0.0 0.032 14.2 0.0 1.4 2 0 0 2 2 2 0 Tyrosine phosphatase family PAC2 PF09754.9 KFR03343.1 - 2.8e-39 135.4 0.0 3.3e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 PAC2 family CEP76-C2 PF15627.6 KFR03344.1 - 1e-61 207.1 0.0 2.1e-61 206.1 0.0 1.5 1 0 0 1 1 1 1 CEP76 C2 domain Transglut_core PF01841.19 KFR03344.1 - 0.011 16.2 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily KIND PF16474.5 KFR03345.1 - 2.7e-46 157.9 2.1 5.3e-46 157.0 0.6 2.2 2 0 0 2 2 2 1 Kinase non-catalytic C-lobe domain Muted PF14942.6 KFR03345.1 - 0.046 14.1 1.7 2.3 8.6 0.5 2.6 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein FYVE PF01363.21 KFR03345.1 - 0.14 12.3 14.7 0.36 11.0 14.7 1.7 1 1 0 1 1 1 0 FYVE zinc finger PRELI PF04707.14 KFR03346.1 - 4.2e-54 182.6 0.0 5.1e-54 182.4 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family PDGLE PF13190.6 KFR03346.1 - 0.047 13.6 0.1 0.093 12.6 0.1 1.4 1 0 0 1 1 1 0 PDGLE domain Baculo_F PF12259.8 KFR03346.1 - 0.087 11.3 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Baculovirus F protein Rep_2 PF01719.17 KFR03346.1 - 0.096 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Plasmid replication protein Peptidase_M41 PF01434.18 KFR03347.1 - 4.8e-66 222.3 0.0 8e-66 221.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KFR03347.1 - 2.1e-42 144.7 0.0 4.4e-42 143.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFR03347.1 - 1.5e-15 56.7 0.1 4.1e-15 55.3 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KFR03347.1 - 8.8e-11 42.1 0.2 3.6e-10 40.2 0.2 2.1 1 0 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.6 KFR03347.1 - 0.00014 22.2 0.0 0.061 13.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFR03347.1 - 0.00088 19.3 0.0 0.0038 17.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFR03347.1 - 0.0016 18.6 0.0 0.0042 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KFR03347.1 - 0.0022 18.4 0.3 0.14 12.6 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KFR03347.1 - 0.0033 17.2 0.0 0.013 15.2 0.0 2.1 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KFR03347.1 - 0.0059 15.9 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KFR03347.1 - 0.037 13.8 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 KFR03347.1 - 0.05 13.8 0.2 0.41 10.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 KFR03347.1 - 0.09 12.1 0.3 0.28 10.5 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KFR03347.1 - 0.1 12.7 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFR03347.1 - 0.15 12.6 0.0 0.51 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KFR03347.1 - 0.21 11.0 0.5 0.64 9.4 0.2 1.8 2 0 0 2 2 2 0 PhoH-like protein Tubulin PF00091.25 KFR03348.1 - 2.2e-60 204.3 0.0 3.7e-60 203.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFR03348.1 - 5.5e-42 142.9 0.1 9.3e-42 142.2 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFR03348.1 - 0.0093 15.7 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KFR03348.1 - 0.023 13.9 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 Tubulin like CIDE-N PF02017.15 KFR03349.1 - 1.2e-29 102.2 0.1 2.7e-29 101.0 0.0 1.6 2 0 0 2 2 2 1 CIDE-N domain Inositol_P PF00459.25 KFR03350.1 - 2e-76 257.1 0.1 2.2e-76 257.0 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family TMF_DNA_bd PF12329.8 KFR03351.1 - 0.00095 19.1 27.0 0.0063 16.5 6.0 3.1 2 2 1 3 3 3 2 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 KFR03351.1 - 0.0018 18.0 2.6 0.0018 18.0 2.6 3.4 2 2 2 4 4 4 1 Septum formation initiator PRKG1_interact PF15898.5 KFR03351.1 - 0.0019 19.1 13.3 0.0019 19.1 13.3 2.0 1 1 1 2 2 2 1 cGMP-dependent protein kinase interacting domain DUF4047 PF13256.6 KFR03351.1 - 0.019 15.2 1.6 0.019 15.2 1.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) Jnk-SapK_ap_N PF09744.9 KFR03351.1 - 0.019 15.2 8.4 0.019 15.2 8.4 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 TMF_TATA_bd PF12325.8 KFR03351.1 - 0.023 14.9 4.0 0.023 14.9 4.0 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding MetOD2 PF18548.1 KFR03351.1 - 0.043 13.9 2.3 0.043 13.9 2.3 2.7 2 1 1 3 3 3 0 Metanogen output domain 2 PsbQ PF05757.11 KFR03351.1 - 0.054 13.2 0.4 0.054 13.2 0.4 1.7 2 1 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) GAS PF13851.6 KFR03351.1 - 0.055 12.8 23.5 0.17 11.2 9.5 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Arc_PepC_II PF06847.11 KFR03351.1 - 0.057 13.9 3.2 2.7 8.6 0.1 2.5 2 1 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II YABBY PF04690.13 KFR03351.1 - 0.11 13.0 6.3 0.18 12.4 6.3 1.3 1 0 0 1 1 1 0 YABBY protein DUF553 PF04473.12 KFR03351.1 - 0.11 12.0 2.0 0.19 11.3 2.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like domain Seryl_tRNA_N PF02403.22 KFR03351.1 - 0.17 12.1 16.1 0.2 11.9 5.4 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BST2 PF16716.5 KFR03351.1 - 0.18 12.4 16.5 0.27 11.9 3.6 2.6 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 ZapB PF06005.12 KFR03351.1 - 0.19 12.2 22.6 0.34 11.4 8.5 2.6 2 1 0 2 2 2 0 Cell division protein ZapB OmpH PF03938.14 KFR03351.1 - 0.24 11.7 11.6 0.1 12.9 3.0 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF2935 PF11155.8 KFR03351.1 - 0.31 11.4 6.8 1.1 9.6 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Spc7 PF08317.11 KFR03351.1 - 0.33 9.8 22.4 0.061 12.2 8.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Nmad5 PF18757.1 KFR03351.1 - 0.65 10.2 9.2 0.44 10.7 6.9 1.8 1 1 0 1 1 1 0 Nucleotide modification associated domain 5 Mod_r PF07200.13 KFR03351.1 - 0.66 10.1 17.6 0.1 12.7 5.7 2.1 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Bacillus_HBL PF05791.11 KFR03351.1 - 0.7 9.7 8.7 0.43 10.4 1.5 2.1 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) YabA PF06156.13 KFR03351.1 - 0.72 10.5 14.7 0.26 11.9 5.3 2.4 1 1 1 2 2 2 0 Initiation control protein YabA DegS PF05384.11 KFR03351.1 - 0.8 9.2 15.5 1.3 8.5 5.2 2.6 2 1 0 2 2 2 0 Sensor protein DegS Herpes_UL6 PF01763.16 KFR03351.1 - 0.84 8.1 11.4 0.054 12.0 3.4 2.0 1 1 1 2 2 2 0 Herpesvirus UL6 like DUF1664 PF07889.12 KFR03351.1 - 0.88 9.6 9.2 2.5 8.1 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4140 PF13600.6 KFR03351.1 - 0.96 9.9 12.5 0.5 10.8 1.1 2.5 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) APG6_N PF17675.1 KFR03351.1 - 1 9.9 24.3 0.32 11.5 11.4 2.8 1 1 0 2 2 2 0 Apg6 coiled-coil region Ubiquitin_4 PF18036.1 KFR03351.1 - 1.3 9.1 0.1 1.3 9.1 0.1 3.0 3 0 0 3 3 3 0 Ubiquitin-like domain DUF3450 PF11932.8 KFR03351.1 - 1.6 8.0 13.4 0.3 10.3 2.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) NRBF2 PF08961.10 KFR03351.1 - 1.6 8.3 14.6 0.026 14.1 4.5 2.1 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator Spc24 PF08286.11 KFR03351.1 - 1.7 8.9 14.3 2.8 8.2 2.7 2.5 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 V_ATPase_I PF01496.19 KFR03351.1 - 1.7 6.5 10.8 2.1 6.2 10.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.16 KFR03351.1 - 1.7 7.4 10.6 2.2 7.1 10.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Exonuc_VII_L PF02601.15 KFR03351.1 - 1.9 8.0 9.3 2.5 7.6 9.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TSC22 PF01166.18 KFR03351.1 - 2.1 8.7 14.5 12 6.3 0.3 3.4 3 0 0 3 3 3 0 TSC-22/dip/bun family bZIP_1 PF00170.21 KFR03351.1 - 2.9 8.1 19.6 0.63 10.2 4.9 3.4 3 0 0 3 3 3 0 bZIP transcription factor ATG16 PF08614.11 KFR03351.1 - 3.4 7.9 17.6 1.3 9.2 3.8 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 KFR03351.1 - 4.2 8.1 8.3 4.5 8.0 1.5 2.5 2 1 0 2 2 2 0 SlyX DUF812 PF05667.11 KFR03351.1 - 4.8 5.9 19.5 82 1.9 19.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF812) GIT_CC PF16559.5 KFR03351.1 - 5.4 7.0 8.4 3.7 7.5 0.4 2.8 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor ADIP PF11559.8 KFR03351.1 - 5.4 7.1 19.3 2.1 8.4 5.3 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4094 PF13334.6 KFR03351.1 - 6.1 7.3 9.2 4.9 7.6 1.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) Cnn_1N PF07989.11 KFR03351.1 - 6.1 7.1 19.8 6.3 7.0 3.4 3.2 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 HDV_ag PF01517.18 KFR03351.1 - 6.7 6.5 10.9 17 5.2 3.3 2.2 1 1 1 2 2 2 0 Hepatitis delta virus delta antigen DUF1640 PF07798.11 KFR03351.1 - 7.1 6.7 15.9 0.2 11.7 5.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) DUF848 PF05852.11 KFR03351.1 - 7.2 6.7 14.6 8.6 6.5 2.1 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF2205 PF10224.9 KFR03351.1 - 9.2 6.3 15.1 0.95 9.5 2.7 2.7 2 1 1 3 3 3 0 Short coiled-coil protein Metallophos PF00149.28 KFR03352.1 - 1.1e-13 52.1 0.0 1.7e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFR03352.1 - 0.00033 20.9 0.0 0.0021 18.2 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain P66_CC PF16563.5 KFR03352.1 - 0.15 11.7 0.1 0.31 10.7 0.1 1.5 1 0 0 1 1 1 0 Coiled-coil and interaction region of P66A and P66B with MBD2 G-alpha PF00503.20 KFR03353.1 - 1.3e-108 363.3 2.3 1.5e-108 363.2 2.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFR03353.1 - 4.4e-16 58.8 2.4 7.6e-13 48.3 0.4 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFR03353.1 - 7e-05 22.5 0.0 0.099 12.2 0.0 2.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFR03353.1 - 0.00011 21.7 2.3 0.0033 16.8 0.2 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KFR03353.1 - 0.00012 22.2 0.9 0.14 12.4 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KFR03353.1 - 0.017 14.5 0.1 0.031 13.7 0.1 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 KFR03353.1 - 0.042 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KFR03353.1 - 0.14 12.3 0.3 8.6 6.5 0.0 2.7 2 2 0 2 2 2 0 50S ribosome-binding GTPase SNAP PF14938.6 KFR03355.1 - 2.3e-26 92.9 9.8 3.2e-26 92.4 9.8 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_MalT PF17874.1 KFR03355.1 - 3.4e-06 26.7 9.2 0.0001 21.8 7.5 2.1 1 1 1 2 2 2 1 MalT-like TPR region TPR_12 PF13424.6 KFR03355.1 - 2.2e-05 24.7 14.3 0.0017 18.6 4.6 3.4 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFR03355.1 - 0.0031 17.6 4.1 4.3 7.8 0.1 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFR03355.1 - 0.011 15.6 6.8 16 5.5 0.3 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat UPF0449 PF15136.6 KFR03355.1 - 0.012 16.1 2.6 0.83 10.2 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 TPR_14 PF13428.6 KFR03355.1 - 0.023 15.5 13.7 2.8 9.0 1.9 5.4 2 1 4 6 6 6 0 Tetratricopeptide repeat NSF PF02071.20 KFR03355.1 - 0.068 13.9 14.1 1.2 10.2 0.5 5.6 5 0 0 5 5 5 0 Aromatic-di-Alanine (AdAR) repeat DUF2150 PF09920.9 KFR03355.1 - 0.14 12.2 1.4 0.27 11.2 0.3 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) TPR_2 PF07719.17 KFR03355.1 - 0.22 11.7 16.5 4 7.8 0.1 6.5 3 2 6 9 9 9 0 Tetratricopeptide repeat TPR_5 PF12688.7 KFR03355.1 - 0.23 11.7 3.9 0.24 11.7 0.4 2.3 2 0 0 2 2 2 0 Tetratrico peptide repeat Sel1 PF08238.12 KFR03355.1 - 0.96 10.2 0.1 0.96 10.2 0.1 3.1 3 1 1 4 4 3 0 Sel1 repeat TPR_19 PF14559.6 KFR03355.1 - 1.4 9.5 14.8 2.7 8.6 0.8 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat MCD_N PF17408.2 KFR03355.1 - 1.7 8.8 4.0 19 5.4 0.3 2.9 3 0 0 3 3 3 0 Malonyl-CoA decarboxylase N-terminal domain TPR_10 PF13374.6 KFR03355.1 - 5.3 7.0 15.1 1.2 9.1 0.1 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat APCDDC PF14921.6 KFR03356.1 - 2e-130 433.3 6.6 1.4e-104 348.7 2.0 2.4 2 1 0 2 2 2 2 Adenomatosis polyposis coli down-regulated 1 CFC PF09443.10 KFR03356.1 - 2.5 8.1 6.3 2.1 8.2 0.1 3.0 3 0 0 3 3 3 0 Cripto_Frl-1_Cryptic (CFC) Motile_Sperm PF00635.26 KFR03358.1 - 1.6e-30 105.2 0.1 2.6e-30 104.5 0.1 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain YabA PF06156.13 KFR03358.1 - 0.012 16.3 0.1 0.023 15.3 0.1 1.4 1 0 0 1 1 1 0 Initiation control protein YabA ASH PF15780.5 KFR03358.1 - 0.02 15.1 0.1 0.039 14.1 0.1 1.5 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin ZapB PF06005.12 KFR03358.1 - 0.061 13.8 0.1 0.099 13.1 0.1 1.3 1 0 0 1 1 1 0 Cell division protein ZapB GIT_CC PF16559.5 KFR03358.1 - 0.066 13.1 0.3 0.14 12.1 0.3 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.21 KFR03358.1 - 0.1 12.7 1.0 0.2 11.8 1.0 1.4 1 0 0 1 1 1 0 bZIP transcription factor Ras PF00071.22 KFR03359.1 - 9.7e-53 178.1 0.0 1.1e-52 177.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR03359.1 - 1e-31 109.7 0.0 1.7e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR03359.1 - 7.8e-11 41.7 0.0 1e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFR03359.1 - 0.0005 20.0 0.0 0.044 13.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KFR03359.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFR03359.1 - 0.026 14.6 0.0 0.042 13.9 0.0 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase MCR_beta PF02241.18 KFR03359.1 - 0.13 11.9 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain RhoGAP PF00620.27 KFR03360.1 - 7.5e-44 149.2 0.3 7.5e-44 149.2 0.3 3.1 2 1 0 3 3 3 2 RhoGAP domain Nod1 PF17114.5 KFR03360.1 - 0.15 12.2 5.3 0.08 13.1 0.6 2.7 2 1 1 3 3 3 0 Gef2-related medial cortical node protein Nod1 Tsg PF04668.12 KFR03362.1 - 9e-46 155.9 6.4 9e-46 155.9 6.4 2.2 2 1 0 2 2 2 1 Twisted gastrulation (Tsg) protein conserved region 2Fe-2S_thioredx PF01257.19 KFR03363.1 - 2.3e-66 222.1 0.1 2.7e-66 221.9 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin SOGA PF11365.8 KFR03365.1 - 5.1e-72 239.1 38.5 8.2e-39 132.6 2.1 5.4 3 2 2 5 5 5 3 Protein SOGA TSC22 PF01166.18 KFR03365.1 - 0.00054 20.2 39.4 0.023 15.0 0.3 6.5 7 1 0 7 7 7 4 TSC-22/dip/bun family DUF948 PF06103.11 KFR03365.1 - 0.032 14.5 6.5 2.5 8.4 0.0 5.1 5 1 1 6 6 6 0 Bacterial protein of unknown function (DUF948) HTH_12 PF08461.10 KFR03365.1 - 7.7 6.6 11.9 17 5.5 0.2 4.3 4 0 0 4 4 4 0 Ribonuclease R winged-helix domain Ras PF00071.22 KFR03366.1 - 2.8e-45 153.8 0.3 3.2e-45 153.6 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR03366.1 - 4e-22 78.7 0.1 7.1e-22 77.9 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR03366.1 - 2.6e-11 43.3 0.3 3.2e-11 43.0 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFR03366.1 - 2e-05 24.2 0.0 3.8e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFR03366.1 - 0.0042 16.5 0.2 0.0045 16.4 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Y_phosphatase PF00102.27 KFR03367.1 - 1.2e-150 499.6 0.1 7.2e-84 281.0 0.1 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 KFR03367.1 - 4.3e-26 91.1 8.1 7.1e-10 39.1 0.0 5.5 5 0 0 5 5 5 3 Fibronectin type III domain MAM PF00629.23 KFR03367.1 - 7.5e-23 81.2 0.0 2.3e-22 79.6 0.0 1.9 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu ig PF00047.25 KFR03367.1 - 1.8e-09 37.6 0.0 6.7e-09 35.8 0.0 2.1 2 0 0 2 2 1 1 Immunoglobulin domain DSPc PF00782.20 KFR03367.1 - 1.1e-08 34.9 0.1 0.0031 17.3 0.0 2.6 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFR03367.1 - 5.2e-05 23.3 0.0 0.011 15.7 0.0 2.5 2 0 0 2 2 2 1 Tyrosine phosphatase family Ig_3 PF13927.6 KFR03367.1 - 0.0001 22.8 0.0 0.00054 20.5 0.0 2.2 2 0 0 2 2 1 1 Immunoglobulin domain PTPlike_phytase PF14566.6 KFR03367.1 - 0.00015 21.9 0.0 0.083 13.0 0.0 2.7 2 0 0 2 2 2 1 Inositol hexakisphosphate Pur_ac_phosph_N PF16656.5 KFR03367.1 - 0.00043 20.8 1.3 0.64 10.6 0.1 3.8 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain I-set PF07679.16 KFR03367.1 - 0.00085 19.3 0.0 0.0021 18.1 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFR03367.1 - 0.00099 19.4 0.0 0.0054 17.0 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain ECSCR PF15820.5 KFR03367.1 - 0.0077 16.0 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator EphA2_TM PF14575.6 KFR03367.1 - 0.038 14.9 0.3 0.17 12.8 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 KFR03367.1 - 0.059 12.2 0.4 0.12 11.2 0.1 1.6 2 0 0 2 2 2 0 Amnionless DUF948 PF06103.11 KFR03367.1 - 0.11 12.7 0.4 0.35 11.2 0.1 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DctM PF06808.12 KFR03367.1 - 0.12 11.2 0.1 0.18 10.6 0.1 1.1 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporter, DctM component LRR_8 PF13855.6 KFR03370.1 - 6.9e-24 83.4 24.1 3.1e-10 39.7 6.3 3.9 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFR03370.1 - 1.7e-19 69.6 46.3 9.9e-07 29.0 4.3 5.5 2 1 7 9 9 9 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFR03370.1 - 1.2e-07 31.3 30.9 0.64 10.8 0.2 9.0 8 1 0 8 8 8 4 Leucine Rich Repeat LRR_9 PF14580.6 KFR03370.1 - 2.5e-06 27.1 10.0 0.008 15.7 2.8 2.2 1 1 1 2 2 2 2 Leucine-rich repeat USP7_C2 PF14533.6 KFR03370.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal LRR_5 PF13306.6 KFR03370.1 - 0.14 12.1 0.6 0.22 11.5 0.6 1.2 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KFR03370.1 - 4.3 7.6 28.1 0.48 10.6 0.4 7.1 9 0 0 9 9 9 0 Leucine Rich repeat AKAP7_NLS PF10469.9 KFR03372.1 - 2.7e-37 128.7 2.0 3e-37 128.5 2.0 1.0 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 KFR03372.1 - 4.9e-07 29.8 0.0 6.3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KFR03372.1 - 0.025 14.7 0.1 1.4 9.2 0.0 2.5 2 1 0 2 2 2 0 LigT like Phosphoesterase Sugar-bind PF04198.13 KFR03372.1 - 0.065 12.3 0.1 0.089 11.9 0.1 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain 4_1_CTD PF05902.13 KFR03373.1 - 8.9e-52 173.7 15.2 8.9e-52 173.7 15.2 3.2 4 0 0 4 4 4 1 4.1 protein C-terminal domain (CTD) SAB PF04382.13 KFR03373.1 - 7.5e-25 86.8 2.5 7.5e-25 86.8 2.5 2.2 2 0 0 2 2 2 1 SAB domain FERM_C PF09380.10 KFR03373.1 - 7.3e-24 84.0 0.0 1.7e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KFR03373.1 - 5.8e-21 74.2 0.1 3.5e-20 71.7 0.1 2.3 2 0 0 2 2 2 1 FERM N-terminal domain FERM_M PF00373.18 KFR03373.1 - 2.3e-19 70.0 4.5 3.1e-19 69.5 0.0 3.2 2 1 1 3 3 3 1 FERM central domain FA PF08736.11 KFR03373.1 - 7.8e-19 67.5 4.3 2.2e-18 66.0 4.3 1.9 1 0 0 1 1 1 1 FERM adjacent (FA) BTB PF00651.31 KFR03374.1 - 2.8e-28 98.4 0.8 5.2e-28 97.5 0.8 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 KFR03374.1 - 1.7e-25 88.0 32.5 2.1e-05 24.7 0.2 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFR03374.1 - 2.8e-23 81.2 47.7 9.3e-07 29.0 2.6 6.5 7 0 0 7 7 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR03374.1 - 2.1e-15 56.1 37.8 0.0043 17.8 1.1 5.8 6 0 0 6 6 5 5 C2H2-type zinc finger zf-met PF12874.7 KFR03374.1 - 2.7e-13 49.8 21.2 0.0051 17.2 0.6 5.6 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFR03374.1 - 2.9e-13 49.7 23.8 0.0063 16.8 0.2 5.8 6 0 0 6 6 5 5 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KFR03374.1 - 0.0097 16.3 36.4 1.3 9.6 6.1 6.6 3 3 2 5 5 5 2 C2HE / C2H2 / C2HC zinc-binding finger zf-MYST PF17772.1 KFR03374.1 - 0.014 15.0 15.2 0.59 9.8 0.2 5.1 3 2 2 5 5 5 0 MYST family zinc finger domain LIM PF00412.22 KFR03374.1 - 0.046 14.0 21.5 0.4 10.9 0.4 4.6 2 2 2 4 4 4 0 LIM domain zf-C2HC_2 PF13913.6 KFR03374.1 - 0.076 12.9 5.6 1.6 8.7 0.1 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type BTB_2 PF02214.22 KFR03374.1 - 0.087 13.2 0.1 0.26 11.6 0.1 1.9 1 0 0 1 1 1 0 BTB/POZ domain zf-C2H2_3rep PF18868.1 KFR03374.1 - 0.11 13.2 14.4 2.7 8.7 2.5 4.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 KFR03374.1 - 0.13 11.9 15.5 1.5 8.5 0.2 5.0 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 KFR03374.1 - 0.19 11.5 9.6 8.8 6.2 0.0 4.5 4 0 0 4 4 4 0 zinc-finger C2H2-type C1_4 PF07975.12 KFR03374.1 - 0.31 11.3 16.0 5.5 7.3 1.7 4.1 1 1 1 3 3 3 0 TFIIH C1-like domain zf-Di19 PF05605.12 KFR03374.1 - 0.68 10.3 23.2 0.42 11.0 3.2 3.3 1 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Yippee-Mis18 PF03226.14 KFR03374.1 - 3 8.1 12.4 4.6 7.5 1.7 3.6 4 0 0 4 4 4 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_15 PF17032.5 KFR03374.1 - 3.8 8.3 17.2 6.1 7.7 2.3 3.7 2 1 3 5 5 4 0 zinc-ribbon family ADK_lid PF05191.14 KFR03374.1 - 4.2 7.4 6.7 7.4 6.7 2.2 3.0 2 1 1 3 3 3 0 Adenylate kinase, active site lid zf-C2H2_6 PF13912.6 KFR03374.1 - 4.8 7.3 32.0 4.5 7.4 0.4 5.8 5 1 0 5 5 5 0 C2H2-type zinc finger zf-trcl PF13451.6 KFR03374.1 - 8.4 6.4 16.6 41 4.2 0.1 5.0 4 1 0 4 4 4 0 Probable zinc-ribbon domain Zn-ribbon_8 PF09723.10 KFR03374.1 - 9.5 6.4 19.9 20 5.4 2.2 4.6 2 2 2 4 4 4 0 Zinc ribbon domain AKAP7_RIRII_bdg PF10470.9 KFR03375.1 - 1.2e-06 28.4 5.3 1.3e-06 28.3 5.3 1.1 1 0 0 1 1 1 1 PKA-RI-RII subunit binding domain of A-kinase anchor protein RVT_1 PF00078.27 KFR03378.1 - 0.0042 16.6 0.0 0.0065 16.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GKAP PF03359.13 KFR03379.1 - 3.2e-155 516.9 5.0 3.2e-155 516.9 5.0 3.0 3 0 0 3 3 3 2 Guanylate-kinase-associated protein (GKAP) protein Homeobox_KN PF05920.11 KFR03380.1 - 0.001 18.9 2.3 0.002 18.0 2.3 1.5 1 0 0 1 1 1 1 Homeobox KN domain EF-hand_7 PF13499.6 KFR03381.1 - 9.7e-14 51.6 6.1 1.1e-07 32.2 0.1 2.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KFR03381.1 - 1.2e-13 49.6 12.0 1.3e-07 30.7 1.6 4.5 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 KFR03381.1 - 1.8e-11 43.0 9.4 7.6e-08 31.7 0.9 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 KFR03381.1 - 3.7e-08 33.1 7.1 0.0025 17.6 0.5 3.7 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KFR03381.1 - 1.6e-05 24.2 4.2 1.8e-05 24.0 1.5 2.5 2 0 0 2 2 2 1 EF hand EF-hand_11 PF08976.11 KFR03381.1 - 2.1e-05 25.3 0.2 0.00077 20.3 0.1 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 KFR03381.1 - 0.0021 18.0 0.0 1.5 8.9 0.0 2.9 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0154) EF-hand_9 PF14658.6 KFR03381.1 - 0.0024 18.2 0.0 1.5 9.2 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain GPHH PF16905.5 KFR03381.1 - 0.015 15.0 0.0 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated SurA_N_2 PF13623.6 KFR03381.1 - 0.02 14.8 0.1 2.4 8.0 0.0 2.1 2 0 0 2 2 2 0 SurA N-terminal domain SPARC_Ca_bdg PF10591.9 KFR03381.1 - 0.024 14.9 0.9 0.043 14.1 0.4 1.6 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2267 PF10025.9 KFR03381.1 - 0.04 14.2 0.0 8.6 6.7 0.0 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2267) DUF2666 PF10869.8 KFR03381.1 - 0.095 12.9 0.0 0.43 10.8 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) DDE_Tnp_IS66_C PF13817.6 KFR03381.1 - 0.13 12.5 0.0 3.2 8.1 0.0 2.6 2 0 0 2 2 2 0 IS66 C-terminal element HLH PF00010.26 KFR03421.1 - 3.9e-12 45.9 0.0 5.8e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain E2F_CC-MB PF16421.5 KFR03422.1 - 5.5e-33 113.2 0.1 8.8e-33 112.5 0.1 1.3 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 KFR03422.1 - 4.8e-25 87.4 0.1 7.5e-25 86.8 0.1 1.3 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain FerA PF08165.11 KFR03422.1 - 0.09 12.7 0.4 0.19 11.7 0.4 1.5 1 0 0 1 1 1 0 FerA (NUC095) domain ArfGap PF01412.18 KFR03423.1 - 5.7e-34 116.7 0.1 2.1e-33 114.9 0.0 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 KFR03423.1 - 4.1e-19 69.2 9.1 7.3e-19 68.4 9.1 1.4 1 0 0 1 1 1 1 BAR domain of APPL family Ank_2 PF12796.7 KFR03423.1 - 1e-15 58.1 2.4 2.5e-08 34.4 0.3 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) PH PF00169.29 KFR03423.1 - 1.2e-11 45.0 1.3 2.8e-11 43.9 0.4 2.1 2 0 0 2 2 2 1 PH domain Ank_5 PF13857.6 KFR03423.1 - 7.4e-09 35.7 0.2 8.9e-08 32.3 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFR03423.1 - 2e-08 33.9 0.1 0.036 14.6 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KFR03423.1 - 6.4e-07 29.8 0.1 3.9e-06 27.3 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KFR03423.1 - 7.4e-06 26.2 0.6 0.00013 22.3 0.2 3.1 2 1 1 3 3 3 1 Ankyrin repeat PH_9 PF15410.6 KFR03423.1 - 0.0068 16.8 0.1 1 9.7 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain DUF3287 PF11690.8 KFR03423.1 - 0.018 14.8 0.1 0.049 13.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) PH_3 PF14593.6 KFR03423.1 - 0.026 14.6 0.1 0.056 13.6 0.1 1.5 1 0 0 1 1 1 0 PH domain PH_2 PF08458.10 KFR03423.1 - 0.056 13.8 0.0 0.19 12.1 0.0 1.9 1 0 0 1 1 1 0 Plant pleckstrin homology-like region TFIIS_M PF07500.14 KFR03424.1 - 6.6e-38 129.6 0.2 1.4e-37 128.6 0.2 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KFR03424.1 - 1.7e-18 66.1 7.1 3.3e-18 65.3 7.1 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KFR03424.1 - 2.2e-12 46.8 0.4 9.6e-12 44.7 0.4 2.1 1 0 0 1 1 1 1 TFIIS helical bundle-like domain 7tm_1 PF00001.21 KFR03425.1 - 7e-57 192.7 18.4 8.5e-57 192.5 18.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFR03425.1 - 2.5e-07 30.4 10.7 4.5e-07 29.5 10.7 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFR03425.1 - 0.00033 20.5 11.7 0.00052 19.8 11.7 1.3 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFR03425.1 - 0.21 11.2 14.9 1.6 8.3 14.9 2.2 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF2207 PF09972.9 KFR03425.1 - 1.4 7.6 7.3 4.1 6.1 3.2 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) RCC1 PF00415.18 KFR03426.1 - 2.5e-48 162.5 13.0 6.2e-13 49.2 0.3 4.1 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFR03426.1 - 6e-14 51.4 23.5 0.0022 17.7 1.7 5.3 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RPEL PF02755.15 KFR03427.1 - 3.3e-25 87.0 13.6 9.5e-09 34.7 2.0 3.6 3 0 0 3 3 3 3 RPEL repeat PA26 PF04636.13 KFR03428.1 - 1.4e-206 686.6 0.1 1.6e-206 686.4 0.1 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) CMD PF02627.20 KFR03428.1 - 0.016 15.3 0.0 0.067 13.2 0.0 2.1 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family FAM76 PF16046.5 KFR03429.1 - 6.5e-99 331.1 35.1 7.4e-99 330.9 35.1 1.0 1 0 0 1 1 1 1 FAM76 protein GHL13 PF14883.6 KFR03429.1 - 0.00098 18.3 3.5 0.0018 17.4 3.4 1.4 1 1 0 1 1 1 1 Hypothetical glycosyl hydrolase family 13 KASH_CCD PF14662.6 KFR03429.1 - 0.031 14.1 3.6 0.031 14.1 3.6 2.9 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH MPS2 PF17060.5 KFR03429.1 - 0.11 11.8 11.8 0.39 9.9 11.8 1.8 1 1 0 1 1 1 0 Monopolar spindle protein 2 CorA PF01544.18 KFR03429.1 - 0.12 11.6 3.2 0.16 11.2 3.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Jnk-SapK_ap_N PF09744.9 KFR03429.1 - 0.31 11.2 17.8 0.25 11.6 9.9 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Baculo_PEP_C PF04513.12 KFR03429.1 - 0.36 10.9 1.8 0.66 10.0 1.8 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF16 PF01519.16 KFR03429.1 - 1 9.9 10.1 0.56 10.7 7.0 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 PSII_Pbs31 PF18240.1 KFR03429.1 - 3.5 8.1 6.6 0.77 10.2 1.9 2.1 2 0 0 2 2 2 0 Photosystem II Psb31 protein TipAS PF07739.13 KFR03429.1 - 3.8 8.1 9.8 0.59 10.7 5.1 2.1 2 2 1 3 3 3 0 TipAS antibiotic-recognition domain Peptidase_C1 PF00112.23 KFR03430.1 - 6.4e-70 235.6 1.2 8.6e-70 235.2 1.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KFR03430.1 - 3.5e-11 43.3 1.2 7.1e-11 42.4 1.2 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KFR03430.1 - 0.00018 20.4 0.1 0.019 13.8 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 KFR03431.1 - 9.5e-71 238.3 1.9 1.2e-70 238.1 1.9 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KFR03431.1 - 5.4e-06 26.8 0.0 9.4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KFR03431.1 - 0.00086 18.2 0.1 0.11 11.3 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Pkinase_Tyr PF07714.17 KFR03432.1 - 9.3e-94 313.5 0.0 1.2e-93 313.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR03432.1 - 2.4e-44 151.7 0.0 3e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFR03432.1 - 7.8e-28 96.4 0.3 1.7e-27 95.3 0.3 1.6 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 KFR03432.1 - 0.00094 19.0 0.1 0.0032 17.3 0.1 2.0 1 0 0 1 1 1 1 Variant SH3 domain Haspin_kinase PF12330.8 KFR03432.1 - 0.001 18.1 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain SH3_1 PF00018.28 KFR03432.1 - 0.006 16.2 0.3 0.027 14.1 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFR03432.1 - 0.0068 16.1 0.2 0.023 14.4 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain APH PF01636.23 KFR03432.1 - 0.02 14.8 0.0 0.33 10.8 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family WH2 PF02205.20 KFR03433.1 - 2.2e-08 33.7 0.0 3.9e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 WH2 motif WASH_WAHD PF11945.8 KFR03433.1 - 0.00044 19.9 0.8 0.037 13.5 0.0 2.2 2 0 0 2 2 2 2 WAHD domain of WASH complex 7tm_1 PF00001.21 KFR03434.1 - 3.1e-37 128.3 23.4 3.8e-37 128.0 23.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFR03434.1 - 0.00086 19.1 19.2 0.034 13.9 19.2 2.7 1 1 0 1 1 1 1 Olfactory receptor Corona_NSP4_C PF16348.5 KFR03434.1 - 0.0074 17.1 0.0 0.016 16.0 0.0 1.6 1 0 0 1 1 1 1 Coronavirus nonstructural protein 4 C-terminus Pkinase PF00069.25 KFR03435.1 - 5.4e-50 170.2 0.0 6.8e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR03435.1 - 2.5e-33 115.5 0.0 1.3e-32 113.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFR03435.1 - 0.0068 15.2 0.0 0.0088 14.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFR03435.1 - 0.011 15.1 0.0 0.15 11.3 0.0 2.0 1 1 0 1 1 1 0 Kinase-like FTA2 PF13095.6 KFR03435.1 - 0.06 13.0 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 KFR03435.1 - 0.15 11.5 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL C2 PF00168.30 KFR03436.1 - 2.6e-36 124.0 0.0 3.3e-19 69.1 0.0 2.1 2 0 0 2 2 2 2 C2 domain DUF778 PF05608.12 KFR03437.1 - 8.9e-43 146.9 5.7 2.1e-21 77.2 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF778) DUF5473 PF17567.2 KFR03438.1 - 0.023 15.0 0.1 0.029 14.7 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5473) WD40 PF00400.32 KFR03439.1 - 1.4e-23 82.7 5.6 2e-06 28.4 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat TPR_19 PF14559.6 KFR03439.1 - 2.4e-07 31.2 1.8 0.0018 18.7 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 KFR03439.1 - 5e-06 26.7 0.1 0.0064 16.8 0.2 4.4 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 KFR03439.1 - 6.2e-06 25.9 8.4 0.051 13.7 0.4 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFR03439.1 - 1.5e-05 25.0 2.2 0.032 14.6 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFR03439.1 - 1.5e-05 24.6 10.4 0.14 12.0 1.0 4.4 3 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFR03439.1 - 2.7e-05 24.3 4.7 5.3e-05 23.4 4.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KFR03439.1 - 3.2e-05 24.4 0.8 0.35 11.8 0.1 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFR03439.1 - 3.9e-05 23.2 1.4 0.00023 20.8 0.9 2.2 2 0 0 2 2 2 1 TPR repeat TPR_6 PF13174.6 KFR03439.1 - 0.00041 20.8 0.3 0.31 11.8 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFR03439.1 - 0.058 14.1 2.8 8.9 7.1 0.1 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFR03439.1 - 0.23 11.6 0.6 1.6 8.9 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFR03439.1 - 0.3 11.4 1.1 9.8 6.7 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Na_H_Exchanger PF00999.21 KFR03440.1 - 2.2e-85 286.8 42.8 2.8e-85 286.4 42.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family OprF PF05736.11 KFR03440.1 - 0.079 12.7 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 OprF membrane domain NTP_transf_7 PF07984.12 KFR03441.1 - 1.2e-143 478.2 0.9 1.4e-143 478.0 0.9 1.0 1 0 0 1 1 1 1 Nucleotidyltransferase DUF4656 PF15551.6 KFR03442.1 - 4.5e-190 631.8 14.0 5.2e-190 631.6 14.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4656) CS PF04969.16 KFR03443.1 - 8.9e-20 71.5 0.5 3.1e-19 69.7 0.1 2.1 2 0 0 2 2 2 1 CS domain NuDC PF16273.5 KFR03443.1 - 4.6e-18 65.5 20.4 4.6e-18 65.5 20.4 3.2 2 2 1 3 3 3 1 Nuclear distribution C domain Nudc_N PF14050.6 KFR03443.1 - 5.5e-13 48.7 0.6 1.9e-12 47.0 0.6 1.9 1 1 0 1 1 1 1 N-terminal conserved domain of Nudc. TAF4 PF05236.14 KFR03443.1 - 0.00046 20.0 6.4 0.00046 20.0 6.4 1.7 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family DUF1682 PF07946.14 KFR03443.1 - 0.67 9.1 12.9 1.7 7.8 12.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) SseC PF04888.12 KFR03443.1 - 9.6 5.7 8.8 21 4.6 8.8 1.5 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Hormone_recep PF00104.30 KFR03444.1 - 1.3e-23 83.6 0.0 1.9e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor G-patch PF01585.23 KFR03445.1 - 9.4e-09 35.0 1.3 1.7e-08 34.2 1.3 1.5 1 0 0 1 1 1 1 G-patch domain 14-3-3 PF00244.20 KFR03446.1 - 9.9e-103 342.4 7.3 1.1e-102 342.2 7.3 1.0 1 0 0 1 1 1 1 14-3-3 protein Anticodon_1 PF08264.13 KFR03446.1 - 0.025 14.5 0.1 0.05 13.6 0.1 1.5 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA Peptidase_C98 PF15499.6 KFR03446.1 - 0.045 13.2 0.1 0.075 12.5 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase FliM PF02154.15 KFR03446.1 - 0.1 12.5 0.2 0.35 10.7 0.0 1.8 2 1 0 2 2 2 0 Flagellar motor switch protein FliM DHHC PF01529.20 KFR03447.1 - 3.6e-36 124.2 10.6 3.6e-36 124.2 10.6 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase HRG PF16954.5 KFR03447.1 - 0.67 10.4 0.1 0.67 10.4 0.1 2.9 3 0 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Mannosyl_trans2 PF04188.13 KFR03448.1 - 5.6e-131 437.9 11.2 6.4e-131 437.7 11.2 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) PMT_2 PF13231.6 KFR03448.1 - 0.00055 20.2 7.2 0.00055 20.2 7.2 2.4 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase BAF250_C PF12031.8 KFR03449.1 - 6.4e-120 399.2 0.0 1.2e-119 398.3 0.0 1.5 1 0 0 1 1 1 1 SWI/SNF-like complex subunit BAF250/Osa ARID PF01388.21 KFR03449.1 - 3.2e-14 53.4 0.0 7.7e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Pkinase PF00069.25 KFR03450.1 - 5.5e-149 494.7 0.0 5e-76 255.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFR03450.1 - 2.3e-78 263.0 0.0 1.9e-41 142.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFR03450.1 - 4e-14 52.6 0.0 5.7e-07 29.1 0.0 3.3 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.14 KFR03450.1 - 4.3e-11 42.6 0.0 2e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFR03450.1 - 3.8e-09 35.8 0.0 0.00048 19.0 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase Haspin_kinase PF12330.8 KFR03450.1 - 1.3e-06 27.6 0.2 0.028 13.4 0.1 2.2 2 0 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 KFR03450.1 - 5.1e-05 23.3 0.0 0.3 11.0 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family FTA2 PF13095.6 KFR03450.1 - 0.00019 21.1 0.1 3.4 7.2 0.0 3.4 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 KFR03450.1 - 0.001 18.6 0.0 0.28 10.7 0.0 2.8 3 0 0 3 3 3 1 PhoP regulatory network protein YrbL Pkinase_C PF00433.24 KFR03450.1 - 0.0024 18.5 0.0 0.01 16.5 0.0 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain tRNA-synt_1f PF01921.18 KFR03450.1 - 0.0036 16.3 0.0 0.0069 15.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (K) RIO1 PF01163.22 KFR03450.1 - 0.03 13.9 0.0 0.82 9.2 0.0 2.4 2 0 0 2 2 2 0 RIO1 family HMG14_17 PF01101.18 KFR03451.1 - 1.5e-25 90.0 20.0 1.6e-25 89.9 20.0 1.0 1 0 0 1 1 1 1 HMG14 and HMG17 Prenyltransf PF01255.19 KFR03452.1 - 4.5e-77 258.6 0.0 6.1e-77 258.1 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase RecX PF02631.16 KFR03452.1 - 4 7.9 7.2 4.7 7.7 0.1 2.6 2 1 0 2 2 2 0 RecX family zf-CCHC PF00098.23 KFR03453.1 - 1.8e-07 30.9 10.8 2.5e-05 24.1 3.0 2.3 2 0 0 2 2 2 2 Zinc knuckle CSD PF00313.22 KFR03453.1 - 1.9e-06 27.6 0.0 3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-CCHC_4 PF14392.6 KFR03453.1 - 0.0073 16.0 8.6 0.066 12.9 1.5 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 KFR03453.1 - 0.053 13.4 6.2 1.6 8.6 0.7 2.4 2 0 0 2 2 2 0 Zinc knuckle CusF_Ec PF11604.8 KFR03453.1 - 0.1 12.6 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF Crystall PF00030.19 KFR03454.1 - 6.1e-125 407.7 0.0 3.5e-25 88.0 0.0 6.2 6 0 0 6 6 6 6 Beta/Gamma crystallin IL4_i_Ig PF18258.1 KFR03454.1 - 9.7e-11 41.7 2.7 2 8.7 0.0 7.5 5 2 1 7 7 7 3 Interleukin-4 inducing immunoglobulin-binding domain Ricin_B_lectin PF00652.22 KFR03454.1 - 4.6e-08 33.4 0.0 7.7e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Inhibitor_I36 PF03995.13 KFR03454.1 - 0.00025 20.9 0.0 44 4.1 0.0 5.9 7 0 0 7 7 7 0 Peptidase inhibitor family I36 Crystall_3 PF08964.10 KFR03454.1 - 0.006 16.7 0.1 3.7 7.8 0.0 4.1 5 1 0 5 5 5 1 Beta/Gamma crystallin RicinB_lectin_2 PF14200.6 KFR03454.1 - 0.072 13.8 0.0 1.1 10.1 0.0 2.4 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like SEP PF08059.13 KFR03455.1 - 1.3e-20 73.8 0.1 7.2e-20 71.4 0.0 2.2 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 KFR03455.1 - 1.7e-10 40.9 0.0 5.2e-09 36.2 0.0 2.5 2 0 0 2 2 2 1 UBX domain TMPIT PF07851.13 KFR03455.1 - 0.031 13.5 1.7 0.044 13.0 1.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein DivIC PF04977.15 KFR03455.1 - 0.088 12.6 3.4 0.22 11.3 3.4 1.6 1 0 0 1 1 1 0 Septum formation initiator Csm1_N PF18504.1 KFR03455.1 - 0.09 13.1 2.4 0.22 11.9 2.4 1.7 1 0 0 1 1 1 0 Csm1 N-terminal domain DUF16 PF01519.16 KFR03455.1 - 0.12 12.9 3.7 0.28 11.7 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF16 FAM76 PF16046.5 KFR03455.1 - 1.3 8.3 5.3 2 7.7 5.3 1.2 1 0 0 1 1 1 0 FAM76 protein SH3BGR PF04908.15 KFR03456.1 - 5.3e-31 106.7 0.1 5.9e-31 106.6 0.1 1.0 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 KFR03456.1 - 1.5e-07 31.5 0.0 2.3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 KFR03456.1 - 0.079 13.4 0.0 0.093 13.2 0.0 1.2 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ATP-synt_Eps PF04627.13 KFR03457.1 - 3.1 7.9 4.3 2.4 8.2 0.8 2.7 2 0 0 2 2 2 0 Mitochondrial ATP synthase epsilon chain zf-C2H2_jaz PF12171.8 KFR03459.1 - 3.5e-09 36.7 3.3 4.6e-09 36.3 3.3 1.2 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFR03459.1 - 0.00041 20.6 0.2 0.00053 20.3 0.2 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFR03459.1 - 0.017 15.5 1.8 0.024 15.0 1.8 1.2 1 0 0 1 1 1 0 Zinc-finger of C2H2 type AKAP95 PF04988.12 KFR03459.1 - 0.021 15.1 0.1 0.023 15.0 0.1 1.2 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.6 KFR03459.1 - 0.059 14.2 1.4 0.1 13.5 1.4 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger TDRP PF15683.5 KFR03460.1 - 0.0093 15.9 0.0 0.017 15.1 0.0 1.6 1 1 1 2 2 2 1 Testis development-related protein Pkinase PF00069.25 KFR03461.1 - 5.1e-52 176.8 0.0 2e-51 174.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR03461.1 - 3.3e-32 111.8 0.4 4.8e-28 98.1 0.4 2.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFR03461.1 - 0.00069 18.5 0.0 0.001 17.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFR03461.1 - 0.0069 16.3 0.2 0.044 13.7 0.1 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KFR03461.1 - 0.015 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFR03461.1 - 0.07 12.1 0.0 0.12 11.3 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KFR03461.1 - 0.081 12.2 0.0 0.2 11.0 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.11 KFR03461.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-RING_UBOX PF13445.6 KFR03462.1 - 1.4e-10 41.0 3.6 4.4e-10 39.4 3.6 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFR03462.1 - 1.8e-08 34.1 2.7 1.8e-08 34.1 2.7 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFR03462.1 - 7.1e-08 32.2 3.4 7.1e-08 32.2 3.4 3.0 2 2 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFR03462.1 - 2.8e-07 30.4 4.9 2.8e-07 30.4 4.9 3.0 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFR03462.1 - 9.7e-07 29.0 5.4 9.7e-07 29.0 5.4 3.1 2 1 0 2 2 1 1 Ring finger domain zf-B_box PF00643.24 KFR03462.1 - 1.4e-06 28.4 6.5 1.4e-06 28.4 6.5 3.7 4 0 0 4 4 4 1 B-box zinc finger zf-C3HC4_3 PF13920.6 KFR03462.1 - 3.1e-06 26.9 7.1 3.1e-06 26.9 7.1 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFR03462.1 - 5.9e-06 26.3 6.6 5.9e-06 26.3 6.6 3.2 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KFR03462.1 - 0.00011 21.9 0.2 0.00011 21.9 0.2 2.3 2 0 0 2 2 2 1 zf-RING of BARD1-type protein SHE3 PF17078.5 KFR03462.1 - 0.0031 17.3 0.1 0.0054 16.5 0.1 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 DUF745 PF05335.13 KFR03462.1 - 0.0068 16.1 2.2 1.1 9.0 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF745) Gp-FAR-1 PF05823.12 KFR03462.1 - 0.085 13.2 0.4 0.2 12.0 0.5 1.6 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Zn-C2H2_12 PF18112.1 KFR03462.1 - 0.77 10.3 5.1 0.7 10.4 1.3 2.8 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_11 PF17123.5 KFR03462.1 - 1.6 8.5 10.5 0.99 9.2 6.2 2.7 2 0 0 2 2 2 0 RING-like zinc finger Cation_efflux PF01545.21 KFR03463.1 - 5.1e-18 65.5 1.3 5.8e-18 65.4 1.3 1.0 1 0 0 1 1 1 1 Cation efflux family Glyco_transf_64 PF09258.10 KFR03464.1 - 2e-64 217.3 0.0 5.1e-64 215.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 KFR03464.1 - 2e-58 198.0 0.0 2.7e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Exostosin family PAF-AH_p_II PF03403.13 KFR03465.1 - 2.8e-51 174.2 0.0 3e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Esterase PF00756.20 KFR03465.1 - 0.0067 16.1 0.0 0.0081 15.8 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KFR03465.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.4 1 1 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KFR03465.1 - 0.12 11.6 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFR03465.1 - 0.12 12.9 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Mito_fiss_reg PF05308.11 KFR03466.1 - 3.7e-73 246.7 1.8 4.4e-73 246.4 1.8 1.1 1 0 0 1 1 1 1 Mitochondrial fission regulator PID PF00640.23 KFR03468.1 - 5.2e-14 52.5 0.2 6.6e-14 52.1 0.2 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID_2 PF14719.6 KFR03468.1 - 2.8e-13 50.1 0.1 3.2e-13 50.0 0.1 1.0 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFR03468.1 - 1.4e-07 31.7 0.0 1.7e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine-binding domain MIF PF01187.18 KFR03468.1 - 0.053 13.8 0.0 0.066 13.5 0.0 1.2 1 0 0 1 1 1 0 Macrophage migration inhibitory factor (MIF) Macoilin PF09726.9 KFR03469.1 - 4.3e-280 931.1 21.9 4.9e-280 930.9 21.9 1.0 1 0 0 1 1 1 1 Macoilin family DUF812 PF05667.11 KFR03469.1 - 0.0019 17.2 41.1 0.0019 17.2 41.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF812) HU-CCDC81_bac_2 PF18175.1 KFR03469.1 - 0.076 12.9 3.7 1.1 9.2 0.1 3.7 2 1 1 3 3 3 0 CCDC81-like prokaryotic HU domain 2 FPP PF05911.11 KFR03469.1 - 0.78 7.8 49.7 0.23 9.6 27.8 2.2 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Mto2_bdg PF12808.7 KFR03469.1 - 2 8.8 18.8 2.1 8.7 1.3 4.3 3 1 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region GLE1 PF07817.13 KFR03469.1 - 4.1 6.5 19.6 0.31 10.2 0.3 2.6 3 0 0 3 3 3 0 GLE1-like protein Ammonium_transp PF00909.21 KFR03470.1 - 2e-44 151.9 18.2 2.5e-44 151.6 18.2 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Phage_holin_8 PF16931.5 KFR03470.1 - 6.8 6.7 11.6 0.78 9.7 0.4 3.2 3 1 0 3 3 3 0 Putative phage holin UPF0220 PF05255.11 KFR03471.1 - 3.1e-47 160.2 4.2 3.5e-47 160.0 4.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) RSRP PF17069.5 KFR03472.1 - 1.6e-54 185.6 81.1 2.1e-54 185.1 81.1 1.2 1 0 0 1 1 1 1 Arginine/Serine-Rich protein 1 SYF2 PF08231.12 KFR03473.1 - 1.1e-56 191.6 10.7 1.1e-56 191.6 10.7 1.9 2 1 0 2 2 2 1 SYF2 splicing factor FUSC-like PF12805.7 KFR03473.1 - 0.0093 15.1 0.2 0.014 14.5 0.2 1.2 1 0 0 1 1 1 1 FUSC-like inner membrane protein yccS rve_3 PF13683.6 KFR03473.1 - 0.029 14.1 0.3 0.48 10.3 0.0 2.5 2 0 0 2 2 2 0 Integrase core domain RunxI PF08504.11 KFR03474.1 - 2.6e-45 153.2 5.9 7.6e-45 151.7 5.9 1.8 1 0 0 1 1 1 1 Runx inhibition domain Runt PF00853.19 KFR03474.1 - 2.9e-16 59.2 0.1 4.7e-16 58.5 0.1 1.3 1 0 0 1 1 1 1 Runt domain GST_C_2 PF13410.6 KFR03476.1 - 3.7e-07 30.1 0.0 7.6e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFR03476.1 - 3.4e-05 24.2 0.0 6.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFR03476.1 - 3.9e-05 23.9 0.0 8.2e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFR03476.1 - 0.0047 17.1 0.2 0.028 14.6 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFR03476.1 - 0.13 12.4 0.1 0.43 10.8 0.0 1.9 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain SKG6 PF08693.10 KFR03477.1 - 0.00069 19.0 1.0 0.001 18.5 1.0 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MscL PF01741.18 KFR03477.1 - 0.0048 17.2 0.1 0.0053 17.0 0.1 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL EptA_B_N PF08019.12 KFR03477.1 - 0.0092 15.9 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoethanolamine transferase EptA/EptB DUF2976 PF11190.8 KFR03477.1 - 0.01 15.6 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) m04gp34like PF12216.8 KFR03477.1 - 0.013 15.0 0.3 0.016 14.8 0.3 1.1 1 0 0 1 1 1 0 Immune evasion protein LrgB PF04172.16 KFR03477.1 - 0.015 14.8 0.2 0.018 14.5 0.2 1.1 1 0 0 1 1 1 0 LrgB-like family DUF2207 PF09972.9 KFR03477.1 - 0.017 13.9 0.0 0.019 13.8 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) NicO PF03824.16 KFR03477.1 - 0.021 14.1 0.0 0.025 14.0 0.0 1.0 1 0 0 1 1 1 0 High-affinity nickel-transport protein RIFIN PF02009.16 KFR03477.1 - 0.023 14.6 0.3 0.027 14.4 0.3 1.0 1 0 0 1 1 1 0 Rifin Adeno_E3_CR2 PF02439.15 KFR03477.1 - 0.026 14.3 2.2 0.043 13.6 2.2 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Glycophorin_A PF01102.18 KFR03477.1 - 0.029 14.6 0.1 0.034 14.4 0.1 1.2 1 0 0 1 1 1 0 Glycophorin A TMEM154 PF15102.6 KFR03477.1 - 0.03 14.2 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 KFR03477.1 - 0.032 15.1 0.0 0.044 14.7 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 KFR03477.1 - 0.034 13.0 0.1 0.035 13.0 0.1 1.0 1 0 0 1 1 1 0 Amnionless Syndecan PF01034.20 KFR03477.1 - 0.047 13.6 0.9 0.068 13.1 0.9 1.2 1 0 0 1 1 1 0 Syndecan domain Presenilin PF01080.17 KFR03477.1 - 0.079 11.7 0.6 0.097 11.4 0.6 1.1 1 0 0 1 1 1 0 Presenilin Shisa PF13908.6 KFR03477.1 - 0.13 12.5 0.1 0.16 12.2 0.1 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EVC2_like PF12297.8 KFR03477.1 - 0.14 10.8 0.0 0.14 10.8 0.0 1.0 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Calcipressin PF04847.12 KFR03478.1 - 6.3e-61 205.4 0.6 8.7e-61 204.9 0.6 1.2 1 0 0 1 1 1 1 Calcipressin RRM_occluded PF16842.5 KFR03478.1 - 0.18 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Mg_trans_NIPA PF05653.14 KFR03479.1 - 3.4e-72 243.0 21.0 4.2e-72 242.8 21.0 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA 7TMR-DISM_7TM PF07695.11 KFR03479.1 - 0.26 11.1 34.5 0.23 11.3 19.2 2.5 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF2663 PF10864.8 KFR03479.1 - 4.5 7.7 6.5 0.5 10.8 0.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2663) CP2 PF04516.15 KFR03480.1 - 2.9e-86 288.5 0.1 3.9e-86 288.1 0.1 1.2 1 0 0 1 1 1 1 CP2 transcription factor Tissue_fac PF01108.17 KFR03481.1 - 1e-23 83.2 0.1 1.8e-23 82.4 0.1 1.4 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.10 KFR03481.1 - 2.1e-08 34.4 0.0 6.7e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.21 KFR03481.1 - 0.00028 21.2 0.9 0.0012 19.1 0.2 2.3 2 1 0 2 2 2 1 Fibronectin type III domain IL6Ra-bind PF09240.10 KFR03481.1 - 0.0038 17.6 0.1 0.0082 16.5 0.1 1.6 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding Tissue_fac PF01108.17 KFR03482.1 - 1.7e-23 82.5 0.2 1.8e-23 82.4 0.2 1.0 1 0 0 1 1 1 1 Tissue factor fn3 PF00041.21 KFR03483.1 - 8.7e-86 282.4 0.0 8.1e-18 64.6 0.0 5.9 5 0 0 5 5 5 5 Fibronectin type III domain I-set PF07679.16 KFR03483.1 - 1.2e-62 208.0 6.0 8.3e-18 64.2 0.3 7.7 7 0 0 7 7 7 7 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR03483.1 - 3.3e-45 152.6 1.4 7.5e-10 39.3 0.0 7.7 7 0 0 7 7 7 7 Immunoglobulin domain ig PF00047.25 KFR03483.1 - 5.8e-30 103.3 7.1 7.6e-05 22.8 0.0 7.7 7 0 0 7 7 7 6 Immunoglobulin domain Ig_2 PF13895.6 KFR03483.1 - 7.4e-26 90.3 3.7 1.8e-05 25.0 0.0 6.7 6 0 0 6 6 6 5 Immunoglobulin domain V-set PF07686.17 KFR03483.1 - 7.6e-18 64.7 19.5 0.087 13.0 0.1 10.4 7 4 1 8 8 8 5 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 KFR03483.1 - 1.3e-09 38.5 1.1 0.082 13.5 0.0 6.9 5 1 0 5 5 5 1 Purple acid Phosphatase, N-terminal domain Tissue_fac PF01108.17 KFR03483.1 - 2.9e-06 27.1 0.2 2.2 8.2 0.0 5.2 5 0 0 5 5 5 2 Tissue factor C2-set_2 PF08205.12 KFR03483.1 - 1.2e-05 25.2 0.2 0.48 10.5 0.0 4.1 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Interfer-bind PF09294.10 KFR03483.1 - 3.9e-05 23.9 0.0 4.9 7.5 0.0 4.5 4 0 0 4 4 4 1 Interferon-alpha/beta receptor, fibronectin type III fn3_2 PF16893.5 KFR03483.1 - 0.00044 20.3 0.0 0.049 13.8 0.0 3.3 2 0 0 2 2 2 1 Fibronectin type III domain DUF4926 PF16277.5 KFR03483.1 - 0.0056 16.0 0.3 0.94 8.9 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4926) NOD2_WH PF17779.1 KFR03483.1 - 0.15 12.4 0.0 89 3.5 0.0 3.6 3 0 0 3 3 3 0 NOD2 winged helix domain Lipocalin_7 PF14651.6 KFR03484.1 - 2e-32 111.8 0.7 2.3e-32 111.6 0.7 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.23 KFR03484.1 - 1.7e-17 64.0 0.8 1.9e-17 63.8 0.8 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family KH_9 PF17904.1 KFR03484.1 - 0.011 16.0 0.0 0.02 15.3 0.0 1.3 1 1 0 1 1 1 0 FMRP KH0 domain RRM_1 PF00076.22 KFR03485.1 - 6.9e-09 35.4 0.0 1.7e-08 34.2 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PNRC PF15365.6 KFR03486.1 - 3.6e-07 29.8 6.7 3.6e-07 29.8 6.7 1.7 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator motif Ribosomal_S20p PF01649.18 KFR03486.1 - 0.0076 16.9 1.3 0.011 16.3 1.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S20 7tm_1 PF00001.21 KFR03487.1 - 7.5e-40 136.9 21.3 7.5e-40 136.9 21.3 1.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFR03487.1 - 3.9e-11 43.2 16.3 1.1e-10 41.8 16.3 1.7 1 1 0 1 1 1 1 Olfactory receptor Alpha_L_fucos PF01120.17 KFR03488.1 - 5.1e-118 394.5 5.7 5.9e-118 394.3 5.7 1.0 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 KFR03488.1 - 1.2e-21 77.1 0.0 3.6e-21 75.5 0.0 1.8 2 0 0 2 2 2 1 Alpha-L-fucosidase C-terminal domain Pacifastin_I PF05375.13 KFR03488.1 - 0.24 11.1 4.7 0.45 10.3 4.7 1.3 1 0 0 1 1 1 0 Pacifastin inhibitor (LCMII) HMGL-like PF00682.19 KFR03489.1 - 9.9e-70 235.1 0.0 1.1e-69 234.9 0.0 1.0 1 0 0 1 1 1 1 HMGL-like AnfO_nitrog PF09582.10 KFR03489.1 - 0.099 12.0 0.0 0.46 9.8 0.0 1.9 2 0 0 2 2 2 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) GDP_Man_Dehyd PF16363.5 KFR03490.1 - 7e-06 25.7 0.0 7.6e-06 25.6 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Abhydrolase_2 PF02230.16 KFR03491.1 - 3.7e-88 295.0 0.0 4.1e-88 294.8 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KFR03491.1 - 3.3e-07 30.4 0.0 5.1e-06 26.5 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFR03491.1 - 1.3e-06 27.9 0.0 0.024 13.9 0.0 2.9 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFR03491.1 - 6e-06 27.0 0.0 7.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KFR03491.1 - 3.8e-05 23.3 0.0 5.6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KFR03491.1 - 0.00018 21.3 0.3 0.016 14.8 0.0 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.13 KFR03491.1 - 0.00038 20.2 0.0 0.0045 16.7 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KFR03491.1 - 0.00064 19.3 0.1 0.091 12.2 0.0 2.7 2 1 1 3 3 3 1 Prolyl oligopeptidase family Cutinase PF01083.22 KFR03491.1 - 0.0026 17.7 0.0 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 Cutinase DUF2974 PF11187.8 KFR03491.1 - 0.0029 17.2 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Palm_thioest PF02089.15 KFR03491.1 - 0.2 11.5 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase AXE1 PF05448.12 KFR03491.1 - 0.21 10.2 0.0 0.36 9.5 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) PITH PF06201.13 KFR03492.1 - 1.4e-31 109.8 0.0 1.7e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 PITH domain Elongin_A PF06881.11 KFR03493.1 - 9.2e-25 87.2 0.0 9.2e-25 87.2 0.0 3.2 3 0 0 3 3 3 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Med26 PF08711.11 KFR03493.1 - 3.2e-13 49.5 0.6 7.6e-13 48.3 0.6 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Kelch_1 PF01344.25 KFR03494.1 - 5e-42 141.2 9.6 1.1e-10 40.9 0.0 6.8 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KFR03494.1 - 4.7e-40 134.6 0.9 3.1e-07 30.5 0.1 5.9 3 1 3 6 6 6 5 Kelch motif BACK PF07707.15 KFR03494.1 - 1.6e-24 85.9 0.0 3.5e-24 84.9 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 KFR03494.1 - 2.1e-23 82.7 0.2 3.9e-23 81.8 0.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.6 KFR03494.1 - 9.5e-23 80.0 10.2 6.5e-07 29.5 0.1 5.4 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KFR03494.1 - 2.7e-18 65.1 1.1 3.5e-05 23.6 0.0 6.4 6 1 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 KFR03494.1 - 4.2e-16 58.7 2.3 0.00018 21.4 0.1 5.6 4 1 1 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KFR03494.1 - 8.4e-11 41.6 1.4 0.32 11.0 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Glyoxal_oxid_N PF07250.11 KFR03494.1 - 0.011 14.9 1.1 0.69 9.1 0.2 2.4 2 0 0 2 2 2 0 Glyoxal oxidase N-terminus DUF1668 PF07893.13 KFR03494.1 - 0.051 12.9 0.0 0.16 11.3 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1668) Ribosomal_L5 PF00281.19 KFR03495.1 - 7.4e-23 80.7 0.0 5.2e-21 74.7 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 KFR03495.1 - 2.9e-21 75.4 0.0 4.6e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus MFS_1 PF07690.16 KFR03496.1 - 1.2e-50 172.5 38.1 1.2e-50 172.5 38.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NCU-G1 PF15065.6 KFR03496.1 - 0.36 9.8 1.4 0.6 9.0 1.4 1.3 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 DUF1435 PF07256.12 KFR03496.1 - 0.49 10.5 7.8 0.16 12.1 1.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) Palm_thioest PF02089.15 KFR03497.1 - 1.3e-75 254.4 0.0 1.5e-75 254.2 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase CAP_N PF01213.19 KFR03498.1 - 5.2e-82 275.9 6.2 2.5e-63 214.5 2.5 2.5 1 1 1 2 2 2 2 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KFR03498.1 - 1.6e-64 216.2 4.8 2.3e-64 215.7 4.8 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 KFR03498.1 - 0.00023 20.9 2.2 0.00058 19.6 2.1 1.6 1 1 0 1 1 1 1 Tubulin binding cofactor C WH2 PF02205.20 KFR03498.1 - 0.072 13.0 0.1 0.17 11.7 0.1 1.7 1 0 0 1 1 1 0 WH2 motif Myc_N PF01056.18 KFR03499.1 - 2.5e-42 146.0 6.6 1.9e-29 103.6 0.5 3.5 1 1 2 3 3 3 3 Myc amino-terminal region HLH PF00010.26 KFR03499.1 - 7.1e-13 48.3 0.2 3.1e-12 46.2 0.5 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF3287 PF11690.8 KFR03499.1 - 0.093 12.5 2.0 0.14 11.8 1.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) DUF1394 PF07159.12 KFR03500.1 - 1.7e-127 424.8 0.1 2.1e-127 424.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) EF-hand_7 PF13499.6 KFR03501.1 - 8.2e-25 87.1 4.1 1.6e-15 57.3 0.9 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KFR03501.1 - 1.1e-23 80.9 15.0 9e-08 31.1 0.1 4.8 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KFR03501.1 - 3.7e-22 76.3 6.3 2.1e-07 30.3 0.1 4.8 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 KFR03501.1 - 1.1e-15 56.3 13.9 5.3e-06 25.7 0.1 4.8 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 KFR03501.1 - 3.2e-12 46.1 12.4 2.8e-06 27.1 1.6 4.0 2 1 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFR03501.1 - 0.0001 22.6 2.7 1.5 9.2 0.0 3.3 1 1 2 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KFR03501.1 - 0.00014 21.9 0.0 0.023 14.9 0.0 2.5 2 0 0 2 2 2 1 Dockerin type I domain Caleosin PF05042.13 KFR03501.1 - 0.00094 19.1 3.6 0.57 10.1 0.1 3.3 1 1 2 3 3 3 1 Caleosin related protein EF-hand_4 PF12763.7 KFR03501.1 - 0.0076 16.2 7.3 5 7.1 0.6 3.6 2 1 2 4 4 4 2 Cytoskeletal-regulatory complex EF hand p25-alpha PF05517.12 KFR03501.1 - 0.0089 16.2 1.0 0.38 10.9 0.3 2.3 2 0 0 2 2 2 1 p25-alpha YxiJ PF14176.6 KFR03501.1 - 0.073 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 YxiJ-like protein EF-hand_10 PF14788.6 KFR03501.1 - 0.89 9.5 3.6 27 4.7 0.2 3.0 3 0 0 3 3 3 0 EF hand 5-nucleotidase PF06189.12 KFR03502.1 - 6.9e-106 353.0 0.0 7.5e-105 349.6 0.0 1.9 1 1 1 2 2 2 2 5'-nucleotidase Hairy_orange PF07527.13 KFR03503.1 - 6.7e-10 39.0 0.0 1.5e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Hairy Orange HLH PF00010.26 KFR03503.1 - 5e-05 23.2 0.0 9.5e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RRM_1 PF00076.22 KFR03504.1 - 1.9e-21 75.6 0.0 3.5e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.21 KFR03504.1 - 1.4e-16 61.1 0.0 2.2e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_5 PF13893.6 KFR03504.1 - 0.0043 16.6 0.0 0.0061 16.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFR03504.1 - 0.017 15.2 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif DUF4944 PF16302.5 KFR03504.1 - 0.03 14.4 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4944) RRM_occluded PF16842.5 KFR03504.1 - 0.05 13.5 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif TGFb_propeptide PF00688.18 KFR03505.1 - 1.9e-45 155.6 0.0 2.6e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 KFR03505.1 - 1.1e-37 129.1 2.9 1.7e-37 128.5 2.9 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain Ndufs5 PF10200.9 KFR03507.1 - 5e-06 26.7 0.1 5.7e-06 26.5 0.1 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Orn_Arg_deC_N PF02784.16 KFR03508.1 - 8.5e-69 231.7 0.0 1e-68 231.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KFR03508.1 - 1.1e-05 25.6 0.0 2.2e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 KFR03508.1 - 0.02 14.4 0.0 0.057 12.9 0.0 1.7 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel ADK PF00406.22 KFR03509.1 - 4.1e-52 176.3 0.0 4.8e-52 176.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.14 KFR03509.1 - 3.2e-16 59.0 0.0 7.9e-16 57.7 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 KFR03509.1 - 1.9e-15 57.5 0.0 4.1e-15 56.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain IBR PF01485.21 KFR03510.1 - 8.2e-14 51.6 34.7 5e-08 33.0 17.0 3.4 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain EF-hand_7 PF13499.6 KFR03511.1 - 2.7e-27 95.0 3.0 6.5e-18 65.0 0.1 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KFR03511.1 - 1.1e-26 90.3 6.2 3e-07 29.5 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFR03511.1 - 1e-23 81.2 1.2 5.5e-07 29.0 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KFR03511.1 - 3.5e-23 80.0 4.8 3.5e-07 29.4 0.2 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KFR03511.1 - 2.1e-19 69.1 4.3 6e-07 29.2 0.2 3.5 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFR03511.1 - 2.3e-07 31.1 0.2 0.0031 17.8 0.1 3.1 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFR03511.1 - 7.6e-07 29.0 0.8 0.28 11.2 0.0 3.4 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 KFR03511.1 - 0.00074 19.3 0.1 1.7 8.5 0.0 3.1 3 0 0 3 3 3 2 EF hand Dockerin_1 PF00404.18 KFR03511.1 - 0.0049 17.0 0.3 5.9 7.2 0.2 2.9 2 1 0 2 2 2 2 Dockerin type I domain DUF832 PF05734.11 KFR03511.1 - 0.083 12.4 0.2 2.2 7.7 0.2 2.0 1 1 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) fn3 PF00041.21 KFR03512.1 - 2.4e-10 40.6 0.4 4.7e-10 39.7 0.1 1.7 2 0 0 2 2 2 1 Fibronectin type III domain DUF4808 PF16066.5 KFR03512.1 - 4.7e-07 30.4 0.0 4.3e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4808) Sigma_reg_N PF13800.6 KFR03512.1 - 0.035 14.4 0.0 0.068 13.5 0.0 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Interfer-bind PF09294.10 KFR03512.1 - 0.17 12.2 1.7 0.2 12.0 0.0 1.9 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III tRNA-synt_1b PF00579.25 KFR03513.1 - 4.8e-76 255.9 0.0 6.1e-76 255.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA_bind PF01588.20 KFR03513.1 - 1e-32 112.1 0.1 2.4e-32 110.9 0.1 1.7 1 0 0 1 1 1 1 Putative tRNA binding domain Filament PF00038.21 KFR03517.1 - 6.4e-20 72.0 35.3 1e-19 71.3 35.3 1.3 1 1 0 1 1 1 1 Intermediate filament protein CENP-H PF05837.12 KFR03517.1 - 0.00038 20.8 7.4 0.00038 20.8 7.4 3.4 2 2 1 3 3 3 1 Centromere protein H (CENP-H) Jnk-SapK_ap_N PF09744.9 KFR03517.1 - 0.00076 19.7 17.9 0.00076 19.7 17.9 2.5 2 1 0 2 2 2 1 JNK_SAPK-associated protein-1 Spc7 PF08317.11 KFR03517.1 - 0.00093 18.2 36.5 0.0024 16.8 15.4 2.3 1 1 0 2 2 2 2 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KFR03517.1 - 0.0033 17.5 4.5 0.0033 17.5 4.5 4.6 2 2 1 3 3 3 2 TPR/MLP1/MLP2-like protein Laminin_II PF06009.12 KFR03517.1 - 0.0037 17.3 17.3 0.041 13.9 4.1 3.0 2 1 1 3 3 3 2 Laminin Domain II Zein-binding PF04576.15 KFR03517.1 - 0.012 15.9 3.6 0.012 15.9 3.6 3.5 3 1 0 3 3 1 0 Zein-binding Cob_adeno_trans PF01923.18 KFR03517.1 - 0.012 15.7 8.9 0.017 15.3 1.1 2.6 2 1 1 3 3 3 0 Cobalamin adenosyltransferase Prp19 PF08606.11 KFR03517.1 - 0.016 15.2 2.9 0.016 15.2 2.9 3.9 4 1 0 4 4 3 0 Prp19/Pso4-like DUF1664 PF07889.12 KFR03517.1 - 0.018 15.1 17.1 0.9 9.6 3.5 3.6 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 KFR03517.1 - 0.067 13.4 3.5 48 4.3 0.0 4.0 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 KFR03517.1 - 0.11 12.5 6.9 4 7.5 0.7 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus HMMR_N PF15905.5 KFR03517.1 - 0.12 11.9 31.0 0.03 13.8 9.5 2.3 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal bZIP_1 PF00170.21 KFR03517.1 - 0.16 12.1 26.5 0.65 10.1 0.3 5.7 5 1 1 6 6 6 0 bZIP transcription factor YabA PF06156.13 KFR03517.1 - 0.19 12.4 29.5 0.15 12.7 3.5 4.9 2 2 2 4 4 4 0 Initiation control protein YabA DUF4972 PF16342.5 KFR03517.1 - 0.23 11.1 4.1 0.32 10.7 0.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4972) CENP-F_leu_zip PF10473.9 KFR03517.1 - 0.24 11.4 43.7 0.16 12.0 10.5 3.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.12 KFR03517.1 - 0.26 11.8 5.1 34 5.0 0.7 3.8 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein BRE1 PF08647.11 KFR03517.1 - 0.31 11.1 24.3 0.16 12.0 6.6 3.5 2 1 1 4 4 4 0 BRE1 E3 ubiquitin ligase Peptidase_M26_C PF07580.14 KFR03517.1 - 0.33 9.4 2.4 0.19 10.2 0.2 1.6 2 0 0 2 2 2 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region Cauli_AT PF03233.13 KFR03517.1 - 0.58 10.1 9.0 0.64 9.9 0.8 2.7 3 0 0 3 3 2 0 Aphid transmission protein Seryl_tRNA_N PF02403.22 KFR03517.1 - 0.63 10.3 25.3 0.53 10.5 6.6 3.6 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TMPIT PF07851.13 KFR03517.1 - 0.7 9.1 19.0 0.13 11.5 4.3 2.8 2 1 1 3 3 3 0 TMPIT-like protein CaKB PF03185.15 KFR03517.1 - 0.73 9.5 3.5 0.45 10.2 1.3 1.8 2 0 0 2 2 2 0 Calcium-activated potassium channel, beta subunit Occludin_ELL PF07303.13 KFR03517.1 - 0.87 10.4 20.1 0.5 11.1 2.7 3.6 2 2 0 3 3 3 0 Occludin homology domain Golgin_A5 PF09787.9 KFR03517.1 - 0.95 8.9 38.9 3.5 7.0 14.5 3.0 1 1 2 3 3 3 0 Golgin subfamily A member 5 PilJ PF13675.6 KFR03517.1 - 0.95 9.5 10.7 0.84 9.7 1.4 3.3 2 2 2 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term Fez1 PF06818.15 KFR03517.1 - 1.2 9.5 33.4 2.4 8.6 12.6 2.3 1 1 1 2 2 2 0 Fez1 GAS PF13851.6 KFR03517.1 - 2.1 7.7 35.9 0.59 9.5 13.2 3.1 2 2 0 2 2 2 0 Growth-arrest specific micro-tubule binding THOC7 PF05615.13 KFR03517.1 - 2.4 8.5 33.3 3.2 8.1 7.9 3.4 2 1 1 3 3 3 0 Tho complex subunit 7 UPF0242 PF06785.11 KFR03517.1 - 3.3 7.8 38.9 1.8 8.6 15.4 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 KFR03517.1 - 3.4 6.7 31.2 0.51 9.4 12.1 2.6 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 TEX13 PF15186.6 KFR03517.1 - 3.5 7.3 27.9 0.44 10.2 1.9 3.9 3 1 1 4 4 4 0 Testis-expressed sequence 13 protein family DUF3450 PF11932.8 KFR03517.1 - 3.5 6.8 29.0 1.6 8.0 0.9 3.7 1 1 3 5 5 5 0 Protein of unknown function (DUF3450) Prominin PF05478.11 KFR03517.1 - 3.8 5.3 18.6 0.33 8.8 7.4 2.2 1 1 1 2 2 2 0 Prominin COG2 PF06148.11 KFR03517.1 - 3.9 7.6 20.3 0.64 10.1 1.6 3.9 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ATG16 PF08614.11 KFR03517.1 - 4.2 7.5 38.2 3.1 8.0 2.4 3.7 2 2 1 3 3 3 0 Autophagy protein 16 (ATG16) MAD PF05557.13 KFR03517.1 - 4.6 5.5 38.7 11 4.2 25.2 2.2 1 1 1 2 2 2 0 Mitotic checkpoint protein Fib_alpha PF08702.10 KFR03517.1 - 5.3 7.2 18.8 1.7 8.8 5.9 2.9 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Mis14 PF08641.12 KFR03517.1 - 6.2 7.1 22.8 3.9 7.8 7.8 3.8 2 2 1 3 3 3 0 Kinetochore protein Mis14 like ADIP PF11559.8 KFR03517.1 - 7.2 6.7 32.0 0.26 11.4 11.0 3.4 2 2 1 3 3 3 0 Afadin- and alpha -actinin-Binding TMF_TATA_bd PF12325.8 KFR03517.1 - 7.7 6.8 38.8 1.2 9.4 9.3 3.8 2 2 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Bacillus_HBL PF05791.11 KFR03517.1 - 8.3 6.2 10.2 17 5.2 1.6 3.2 2 2 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) CAF1C_H4-bd PF12265.8 KFR03518.1 - 2.5e-28 98.1 0.8 3.6e-27 94.4 0.2 2.9 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KFR03518.1 - 1.1e-26 92.6 14.7 3.2e-07 30.9 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR03518.1 - 6.4e-05 23.2 1.2 0.013 15.8 0.0 3.6 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFR03518.1 - 0.00014 21.8 0.6 0.024 14.5 0.0 3.1 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Capsid_NCLDV PF04451.12 KFR03518.1 - 0.071 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein Archease PF01951.16 KFR03519.1 - 8.7e-45 152.3 0.1 1.1e-44 152.1 0.1 1.1 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) BTB PF00651.31 KFR03520.1 - 8.9e-26 90.3 0.5 1.8e-25 89.4 0.5 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFR03520.1 - 1e-08 35.2 2.6 1e-08 35.2 2.6 3.7 3 0 0 3 3 2 1 Zinc-finger double domain DUF3342 PF11822.8 KFR03520.1 - 1.7e-05 24.9 0.1 3.7e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) zf-C2H2 PF00096.26 KFR03520.1 - 0.00026 21.2 1.5 0.00026 21.2 1.5 3.9 5 0 0 5 5 3 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFR03520.1 - 0.00084 19.0 3.6 0.00084 19.0 3.6 2.4 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-met PF12874.7 KFR03520.1 - 0.0016 18.7 2.2 0.06 13.8 0.1 3.3 3 0 0 3 3 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFR03520.1 - 0.0023 18.6 1.2 0.0023 18.6 1.2 3.9 4 0 0 4 4 3 2 C2H2-type zinc finger BTB_2 PF02214.22 KFR03520.1 - 0.019 15.3 0.2 0.066 13.6 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain Zn-ribbon_8 PF09723.10 KFR03520.1 - 0.019 15.1 0.8 0.019 15.1 0.8 3.0 3 0 0 3 3 2 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 KFR03520.1 - 0.039 14.2 1.5 0.77 10.1 0.1 3.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Trm112p PF03966.16 KFR03520.1 - 0.063 13.9 1.8 0.21 12.2 1.8 1.9 1 0 0 1 1 1 0 Trm112p-like protein DUF3212 PF11486.8 KFR03520.1 - 0.063 13.3 0.2 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3212) Prim_Zn_Ribbon PF08273.12 KFR03520.1 - 0.12 12.6 0.4 0.12 12.6 0.4 2.2 2 0 0 2 2 1 0 Zinc-binding domain of primase-helicase PHF5 PF03660.14 KFR03520.1 - 0.37 11.0 6.4 6.2 7.1 0.8 2.5 1 1 1 2 2 2 0 PHF5-like protein zf-Di19 PF05605.12 KFR03520.1 - 0.39 11.0 11.0 0.23 11.8 6.9 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Elf1 PF05129.13 KFR03520.1 - 1 9.5 8.5 1.8 8.7 2.5 3.0 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zinc_ribbon_10 PF10058.9 KFR03520.1 - 1.5 8.6 8.7 4.6 7.0 1.7 2.9 3 0 0 3 3 2 0 Predicted integral membrane zinc-ribbon metal-binding protein PBP1_TM PF14812.6 KFR03520.1 - 2 8.8 5.7 18 5.8 0.0 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Lar_restr_allev PF14354.6 KFR03520.1 - 6.4 7.2 9.3 12 6.4 3.2 3.3 2 1 0 2 2 2 0 Restriction alleviation protein Lar BTB PF00651.31 KFR03521.1 - 2.1e-26 92.3 0.4 3.5e-26 91.6 0.4 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFR03521.1 - 1.3e-08 34.9 2.4 1.3e-08 34.9 2.4 3.8 3 0 0 3 3 3 1 Zinc-finger double domain DUF3342 PF11822.8 KFR03521.1 - 4.8e-06 26.7 0.1 1.3e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) zf-C2H2 PF00096.26 KFR03521.1 - 0.00018 21.8 1.7 0.00018 21.8 1.7 3.8 4 0 0 4 4 3 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFR03521.1 - 0.00022 20.9 2.9 0.00022 20.9 2.9 2.6 4 0 0 4 4 3 1 C2H2-type zinc-finger domain BTB_2 PF02214.22 KFR03521.1 - 0.0014 19.0 0.0 0.0028 18.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.6 KFR03521.1 - 0.0021 18.8 1.5 0.0021 18.8 1.5 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 KFR03521.1 - 0.014 15.8 2.6 0.17 12.3 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf_UBZ PF18439.1 KFR03521.1 - 5.6 6.7 6.4 3.4 7.4 0.1 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 KFR03521.1 - 7.7 6.9 13.3 0.42 11.0 6.4 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-CHY PF05495.12 KFR03521.1 - 9.7 6.8 13.1 14 6.2 11.9 2.0 1 1 0 1 1 1 0 CHY zinc finger BTB PF00651.31 KFR03522.1 - 4.2e-26 91.3 0.2 7.1e-26 90.6 0.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFR03522.1 - 3.8e-09 36.5 1.0 3.8e-09 36.5 1.0 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFR03522.1 - 1e-05 25.2 0.1 4.5e-05 23.1 0.1 2.2 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFR03522.1 - 1.4e-05 25.2 1.4 1.4e-05 25.2 1.4 4.6 5 0 0 5 5 5 1 Zinc finger, C2H2 type DUF3342 PF11822.8 KFR03522.1 - 2.2e-05 24.6 0.0 5.4e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3342) zf-C2H2_4 PF13894.6 KFR03522.1 - 0.0046 17.7 1.4 0.0046 17.7 1.4 5.1 6 0 0 6 6 6 1 C2H2-type zinc finger zf-met PF12874.7 KFR03522.1 - 0.021 15.2 0.1 0.021 15.2 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Herpes_ori_bp PF02399.15 KFR03522.1 - 0.079 11.0 0.3 0.13 10.2 0.3 1.3 1 0 0 1 1 1 0 Origin of replication binding protein zf-C2H2_jaz PF12171.8 KFR03522.1 - 0.17 12.2 1.6 2.2 8.7 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KFR03522.1 - 8.5 6.6 9.4 0.53 10.4 0.7 2.8 2 0 0 2 2 2 0 Zinc ribbon domain BSD PF03909.17 KFR03523.1 - 1.9e-19 69.4 2.8 2.5e-18 65.8 0.3 2.4 2 0 0 2 2 2 2 BSD domain Arm PF00514.23 KFR03524.1 - 3.1e-90 293.8 21.9 1.2e-13 50.5 0.0 9.0 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KFR03524.1 - 5.6e-25 87.6 1.7 5.6e-25 87.6 1.7 1.8 2 0 0 2 2 1 1 Importin beta binding domain Arm_3 PF16186.5 KFR03524.1 - 1.1e-22 79.3 3.0 2.1e-22 78.4 1.9 2.1 3 0 0 3 3 3 1 Atypical Arm repeat HEAT_2 PF13646.6 KFR03524.1 - 3.8e-21 75.3 0.0 2.5e-07 31.0 0.0 5.0 3 2 2 5 5 4 4 HEAT repeats HEAT_EZ PF13513.6 KFR03524.1 - 7e-21 74.3 6.2 7.2e-07 29.6 0.0 6.2 5 2 2 7 7 7 3 HEAT-like repeat HEAT PF02985.22 KFR03524.1 - 8.6e-14 50.5 8.3 0.0031 17.6 0.0 7.8 9 0 0 9 9 9 2 HEAT repeat V-ATPase_H_C PF11698.8 KFR03524.1 - 3.6e-06 27.1 0.0 0.24 11.5 0.0 4.3 3 2 1 4 4 4 2 V-ATPase subunit H RICTOR_V PF14668.6 KFR03524.1 - 4.8e-06 26.7 1.4 0.71 10.1 0.0 4.8 4 1 1 5 5 4 1 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.13 KFR03524.1 - 1.5e-05 24.6 0.1 0.1 12.1 0.0 2.8 1 1 1 2 2 2 2 Armadillo-like HEAT_PBS PF03130.16 KFR03524.1 - 0.00052 20.4 0.2 8.7 7.3 0.0 4.9 5 0 0 5 5 4 1 PBS lyase HEAT-like repeat CTNNBL PF08216.11 KFR03524.1 - 0.014 15.6 0.0 3.2 8.0 0.0 3.9 4 0 0 4 4 4 0 Catenin-beta-like, Arm-motif containing nuclear SEN1_N PF12726.7 KFR03524.1 - 0.039 12.2 0.0 4.6 5.3 0.0 2.7 2 1 1 3 3 3 0 SEN1 N terminal NUSAP PF16006.5 KFR03524.1 - 1.5 8.5 6.1 2.1 8.0 6.1 1.2 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein PAH PF02671.21 KFR03524.1 - 7.8 6.7 5.9 1.5 9.0 0.9 2.5 2 1 1 3 3 3 0 Paired amphipathic helix repeat Taxilin PF09728.9 KFR03525.1 - 5e-118 393.8 79.4 5.6e-118 393.6 79.4 1.0 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Phage_GPL PF05926.11 KFR03525.1 - 1.2 9.2 12.2 0.12 12.4 3.2 2.9 2 2 0 2 2 2 0 Phage head completion protein (GPL) DUF3450 PF11932.8 KFR03525.1 - 3.6 6.8 57.4 0.42 9.9 10.2 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF3450) SpoVAD PF07451.11 KFR03525.1 - 6.8 5.3 7.7 8.7 4.9 0.7 2.3 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) HTH_26 PF13443.6 KFR03525.1 - 9.5 6.7 8.4 0.59 10.6 0.6 3.3 4 2 0 4 4 4 0 Cro/C1-type HTH DNA-binding domain IQ PF00612.27 KFR03526.1 - 0.011 15.5 0.5 0.036 13.8 0.5 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif DCX PF03607.17 KFR03527.1 - 1.8e-21 76.0 0.0 2.2e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Doublecortin DCX PF03607.17 KFR03528.1 - 8e-16 57.9 0.0 1.1e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Doublecortin TMEM234 PF10639.9 KFR03529.1 - 9.6e-24 83.6 1.6 1.1e-23 83.5 1.6 1.0 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 KFR03529.1 - 0.013 15.7 2.3 0.014 15.5 2.3 1.0 1 0 0 1 1 1 0 EamA-like transporter family WD40 PF00400.32 KFR03530.1 - 1.1e-26 92.5 1.5 1.3e-06 29.0 2.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR03530.1 - 7e-12 45.5 0.0 0.16 12.3 0.0 5.1 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFR03530.1 - 0.00071 18.6 0.2 0.62 9.0 0.0 3.1 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ISN1 PF06437.11 KFR03530.1 - 0.0063 15.5 0.1 0.7 8.7 0.0 2.0 2 0 0 2 2 2 2 IMP-specific 5'-nucleotidase Nup160 PF11715.8 KFR03530.1 - 0.031 12.9 0.5 1.9 7.0 0.1 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Myotub-related PF06602.14 KFR03531.1 - 7.5e-89 298.1 0.0 9.2e-89 297.8 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain PhoH PF02562.16 KFR03531.1 - 0.25 10.8 0.0 0.47 9.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein 3-PAP PF12578.8 KFR03531.1 - 0.28 10.9 2.6 1 9.1 2.6 1.8 1 1 0 1 1 1 0 Myotubularin-associated protein FAM167 PF11652.8 KFR03532.1 - 5.4e-38 129.3 1.4 8.1e-38 128.8 1.4 1.3 1 0 0 1 1 1 1 FAM167 DUF2388 PF09498.10 KFR03532.1 - 0.00017 21.5 0.2 0.00035 20.5 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2388) APG6_N PF17675.1 KFR03532.1 - 0.003 18.1 0.1 0.0036 17.8 0.1 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region ATG16 PF08614.11 KFR03532.1 - 0.0034 17.6 0.4 0.0041 17.4 0.4 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4618 PF15397.6 KFR03532.1 - 0.014 14.8 0.2 0.02 14.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) IATP PF04568.12 KFR03532.1 - 0.022 15.2 0.2 0.035 14.5 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Snapin_Pallidin PF14712.6 KFR03532.1 - 0.053 13.9 2.5 0.14 12.6 2.6 1.6 1 1 0 1 1 1 0 Snapin/Pallidin DUF4404 PF14357.6 KFR03532.1 - 0.06 14.0 1.8 0.098 13.3 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) PEP-utilisers_N PF05524.13 KFR03532.1 - 0.067 13.4 0.1 0.095 12.9 0.1 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal LURAP PF14854.6 KFR03532.1 - 0.082 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Leucine rich adaptor protein DUF4164 PF13747.6 KFR03532.1 - 0.087 13.1 2.6 0.18 12.1 2.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Pkinase_Tyr PF07714.17 KFR03533.1 - 6.4e-97 323.9 0.0 8e-97 323.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR03533.1 - 3.8e-50 170.7 0.0 4.9e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFR03533.1 - 7.7e-28 96.4 0.5 1.4e-27 95.5 0.5 1.5 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFR03533.1 - 9.8e-15 53.9 0.1 2.4e-14 52.7 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFR03533.1 - 3.3e-10 39.7 0.0 6.8e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFR03533.1 - 3.1e-08 33.2 0.0 7.2e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Haspin_kinase PF12330.8 KFR03533.1 - 0.00058 18.9 0.0 0.00083 18.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain SH3_3 PF08239.11 KFR03533.1 - 0.06 13.6 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Kdo PF06293.14 KFR03533.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Hist_deacetyl PF00850.19 KFR03534.1 - 1.9e-84 283.8 0.1 3e-84 283.1 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain MARCKS PF02063.17 KFR03535.1 - 3.1e-12 47.1 48.4 7.5e-12 45.8 48.4 1.6 1 1 0 1 1 1 1 MARCKS family Tmp39 PF10271.9 KFR03536.1 - 5.1e-210 697.9 18.8 5.9e-210 697.7 18.8 1.0 1 0 0 1 1 1 1 Putative transmembrane protein Sam68-YY PF16568.5 KFR03537.1 - 3.3e-15 56.6 36.2 5.4e-15 55.9 36.2 1.4 1 0 0 1 1 1 1 Tyrosine-rich domain of Sam68 KH_1 PF00013.29 KFR03537.1 - 2.8e-11 43.1 0.0 5e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 KH domain Qua1 PF16274.5 KFR03537.1 - 1.3e-10 40.9 0.6 1.3e-10 40.9 0.6 1.9 2 0 0 2 2 2 1 Qua1 domain KH_5 PF13184.6 KFR03537.1 - 0.18 11.9 0.0 0.31 11.2 0.0 1.3 1 0 0 1 1 1 0 NusA-like KH domain Y_phosphatase PF00102.27 KFR03538.1 - 1.2e-07 31.6 0.0 3.8e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFR03538.1 - 2e-07 30.9 0.0 3.2e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFR03538.1 - 0.18 11.8 0.2 0.33 10.9 0.2 1.3 1 1 0 1 1 1 0 Tyrosine phosphatase family TAT_ubiq PF07706.12 KFR03539.1 - 0.011 16.0 1.5 7.7 6.8 0.5 3.9 3 1 0 3 3 3 0 Aminotransferase ubiquitination site Collagen PF01391.18 KFR03541.1 - 1.1e-23 82.8 94.3 9.6e-10 38.1 26.2 4.6 4 1 1 5 5 5 4 Collagen triple helix repeat (20 copies) EF-hand_1 PF00036.32 KFR03542.1 - 3.6e-18 63.7 0.1 1.1e-06 27.8 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFR03542.1 - 1.9e-17 61.6 0.2 1.5e-06 27.7 0.0 3.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 KFR03542.1 - 1.7e-15 57.2 0.3 7.8e-07 29.5 0.0 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFR03542.1 - 1.8e-15 55.6 0.8 1.1e-05 24.7 0.1 3.6 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KFR03542.1 - 2.1e-10 40.3 0.1 0.018 14.8 0.0 4.2 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 KFR03542.1 - 0.00023 21.4 0.0 4.6 7.6 0.0 3.6 4 1 0 4 4 4 2 EF-hand domain EF-hand_2 PF09068.11 KFR03542.1 - 0.0064 16.6 0.3 1.2 9.2 0.0 2.8 2 2 2 4 4 4 1 EF hand Caleosin PF05042.13 KFR03542.1 - 0.048 13.6 0.0 0.23 11.4 0.0 1.9 1 1 1 2 2 2 0 Caleosin related protein Gelsolin PF00626.22 KFR03542.1 - 0.06 13.2 2.0 0.11 12.4 1.9 1.5 1 1 0 1 1 1 0 Gelsolin repeat Peptidase_C1 PF00112.23 KFR03543.1 - 1.1e-24 87.7 0.1 1.9e-24 87.0 0.1 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Pacifastin_I PF05375.13 KFR03543.1 - 1.2e-06 28.2 3.7 5e-06 26.1 3.7 2.1 1 0 0 1 1 1 1 Pacifastin inhibitor (LCMII) Somatomedin_B PF01033.17 KFR03543.1 - 0.00094 19.5 15.2 0.00094 19.5 15.2 2.8 2 1 0 2 2 2 1 Somatomedin B domain KCNQ_channel PF03520.14 KFR03544.1 - 1.4e-89 299.0 0.2 1.9e-89 298.6 0.2 1.2 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel Ion_trans_2 PF07885.16 KFR03545.1 - 6.8e-16 58.0 4.0 7.8e-16 57.8 4.0 1.1 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 KFR03545.1 - 6.4e-08 32.1 2.3 7e-08 32.0 2.3 1.1 1 0 0 1 1 1 1 Ion transport protein Lig_chan PF00060.26 KFR03545.1 - 0.013 15.3 3.8 0.037 13.9 3.8 1.6 1 1 0 1 1 1 0 Ligand-gated ion channel DUF2798 PF11391.8 KFR03545.1 - 0.057 13.5 3.5 0.7 10.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) FAD-SLDH PF12318.8 KFR03545.1 - 0.1 12.6 1.0 0.14 12.2 1.0 1.2 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase CBFD_NFYB_HMF PF00808.23 KFR03546.1 - 1.1e-21 76.9 2.4 3.8e-21 75.1 1.6 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFR03546.1 - 1.6e-15 57.6 0.9 1.6e-15 57.6 0.9 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KFR03546.1 - 0.043 14.1 0.1 0.1 12.9 0.1 1.7 1 0 0 1 1 1 0 CENP-S associating Centromere protein X C2 PF00168.30 KFR03547.1 - 1.6e-16 60.5 0.0 2.6e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain ArfGap PF01412.18 KFR03548.1 - 1.8e-33 115.0 0.1 3.6e-33 114.1 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf CUB PF00431.20 KFR03549.1 - 3.2e-281 912.6 0.0 4.1e-26 91.5 0.0 12.3 12 0 0 12 12 12 12 CUB domain Sushi PF00084.20 KFR03549.1 - 3.4e-262 847.4 162.6 1.3e-12 48.1 0.6 27.4 27 0 0 27 27 27 27 Sushi repeat (SCR repeat) CUB_2 PF02408.20 KFR03549.1 - 3.2e-21 75.3 22.8 0.00022 21.0 0.6 11.1 12 0 0 12 12 12 6 CUB-like domain HRM PF02793.22 KFR03549.1 - 0.0013 19.0 80.1 0.45 10.8 0.1 16.6 15 1 1 16 16 16 6 Hormone receptor domain CUB PF00431.20 KFR03550.1 - 1.1e-21 77.3 0.0 1.4e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 CUB domain Sushi PF00084.20 KFR03550.1 - 8e-09 36.0 0.2 1.3e-08 35.3 0.2 1.4 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) DUF4688 PF15752.5 KFR03551.1 - 7.6e-13 48.4 4.0 1.7e-11 44.0 4.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4688) DUF4688 PF15752.5 KFR03552.1 - 6.5e-45 154.0 21.6 7.1e-45 153.9 21.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4688) Connexin PF00029.19 KFR03553.1 - 9.8e-81 270.9 9.1 2.9e-79 266.1 9.1 2.0 1 1 0 1 1 1 1 Connexin 7tm_1 PF00001.21 KFR03553.1 - 0.0011 18.3 3.6 0.26 10.6 1.1 2.1 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) DUF3404 PF11884.8 KFR03553.1 - 0.0071 15.6 0.1 0.012 14.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3404) UbiA PF01040.18 KFR03553.1 - 0.031 13.6 0.1 0.07 12.4 0.0 1.6 2 0 0 2 2 2 0 UbiA prenyltransferase family Ninjurin PF04923.12 KFR03553.1 - 0.24 11.3 2.6 0.98 9.4 0.0 2.8 2 1 1 3 3 3 0 Ninjurin Connexin PF00029.19 KFR03554.1 - 8.7e-101 336.6 1.9 1e-100 336.3 1.9 1.1 1 0 0 1 1 1 1 Connexin Connexin43 PF03508.13 KFR03554.1 - 0.0046 16.5 5.5 0.0095 15.5 5.5 1.5 1 0 0 1 1 1 1 Gap junction alpha-1 protein (Cx43) KELK PF15796.5 KFR03554.1 - 0.08 13.4 1.4 0.14 12.7 1.4 1.3 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase UPF0767 PF15990.5 KFR03555.1 - 4.1e-34 116.6 0.0 4.6e-34 116.4 0.0 1.0 1 0 0 1 1 1 1 UPF0767 family GKAP PF03359.13 KFR03556.1 - 1.2e-158 528.1 6.2 3.6e-158 526.6 6.2 1.8 1 0 0 1 1 1 1 Guanylate-kinase-associated protein (GKAP) protein CENP-U PF13097.6 KFR03556.1 - 0.34 10.8 10.2 1.3 8.9 2.5 2.8 2 0 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit DoxX_2 PF13564.6 KFR03557.1 - 0.014 15.4 0.1 0.015 15.4 0.1 1.1 1 0 0 1 1 1 0 DoxX-like family DoxX PF07681.12 KFR03557.1 - 0.029 14.9 0.1 0.03 14.9 0.1 1.1 1 0 0 1 1 1 0 DoxX RRM_1 PF00076.22 KFR03558.1 - 1.5e-30 104.9 0.1 7.3e-15 54.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.11 KFR03558.1 - 1.1e-24 86.3 1.0 2.8e-24 85.0 1.0 1.8 1 0 0 1 1 1 1 NOPS (NUC059) domain RRM_7 PF16367.5 KFR03558.1 - 0.0015 18.6 0.0 0.014 15.5 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif AAA_21 PF13304.6 KFR03558.1 - 0.071 12.9 0.3 0.11 12.2 0.3 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF5401 PF17380.2 KFR03558.1 - 2.9 5.8 26.4 4.2 5.3 26.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF4407 PF14362.6 KFR03558.1 - 6.2 6.1 9.8 8.9 5.6 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ifi-6-16 PF06140.13 KFR03559.1 - 1.1e-22 79.7 26.5 1.3e-22 79.5 26.5 1.1 1 0 0 1 1 1 1 Interferon-induced 6-16 family Y_Y_Y PF07495.13 KFR03560.1 - 6.4e-13 48.5 1.0 0.0057 16.6 0.0 5.2 5 0 0 5 5 5 3 Y_Y_Y domain PKD PF00801.20 KFR03560.1 - 2.3e-12 46.6 9.0 0.0067 16.2 0.1 5.6 5 0 0 5 5 5 3 PKD domain Big_9 PF17963.1 KFR03560.1 - 3.2e-11 43.8 30.9 0.00045 20.9 1.7 5.4 5 0 0 5 5 5 4 Bacterial Ig domain DUF4625 PF15418.6 KFR03560.1 - 1.5e-10 41.4 0.3 0.26 11.5 0.0 4.5 4 0 0 4 4 4 4 Domain of unknown function (DUF4625) He_PIG PF05345.12 KFR03560.1 - 8.4e-07 29.1 3.8 0.34 11.1 0.0 5.1 5 0 0 5 5 5 2 Putative Ig domain DUF4998 PF16389.5 KFR03560.1 - 2.1e-06 27.5 1.2 0.5 9.9 0.0 4.2 4 0 0 4 4 4 3 Domain of unknown function DUF5013 PF16405.5 KFR03560.1 - 0.00015 22.1 0.8 0.2 11.9 0.0 4.0 4 1 0 4 4 4 1 Domain of unknown function (DUF5013) Wzt_C PF14524.6 KFR03560.1 - 0.0005 20.1 0.0 5.6 7.0 0.0 4.2 4 0 0 4 4 4 1 Wzt C-terminal domain AMPK1_CBM PF16561.5 KFR03560.1 - 0.0011 19.1 2.5 13 6.1 0.0 5.6 7 0 0 7 7 7 0 Glycogen recognition site of AMP-activated protein kinase fn3 PF00041.21 KFR03560.1 - 0.0063 16.8 0.3 0.6 10.5 0.0 3.7 3 0 0 3 3 3 1 Fibronectin type III domain Cadherin_5 PF17892.1 KFR03560.1 - 0.0081 16.1 4.0 2.3 8.3 0.1 4.2 4 0 0 4 4 4 1 Cadherin-like domain DUF5011 PF16403.5 KFR03560.1 - 0.11 12.6 10.3 31 4.8 0.1 5.0 5 0 0 5 5 5 0 Domain of unknown function (DUF5011) TMEM154 PF15102.6 KFR03560.1 - 0.19 11.6 2.2 0.35 10.8 0.0 2.3 2 0 0 2 2 2 0 TMEM154 protein family CopC PF04234.12 KFR03560.1 - 0.26 12.3 6.9 16 6.6 0.0 4.6 5 0 0 5 5 4 0 CopC domain EGF_2 PF07974.13 KFR03560.1 - 3.7 8.0 13.0 0.055 13.8 5.0 2.1 2 0 0 2 2 1 0 EGF-like domain PAN_4 PF14295.6 KFR03560.1 - 8.3 6.4 11.2 17 5.4 6.1 2.5 2 0 0 2 2 2 0 PAN domain Neurochondrin PF05536.11 KFR03561.1 - 8.5e-250 830.3 0.2 9.7e-250 830.1 0.2 1.0 1 0 0 1 1 1 1 Neurochondrin TF_AP-2 PF03299.14 KFR03562.1 - 7e-86 287.2 0.0 8.2e-86 287.0 0.0 1.0 1 0 0 1 1 1 1 Transcription factor AP-2 Proteasome PF00227.26 KFR03563.1 - 2.3e-42 144.6 0.0 2.7e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF4653 PF15546.6 KFR03564.1 - 7e-80 268.3 0.0 8.2e-80 268.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4653) Piwi PF02171.17 KFR03566.1 - 1.6e-109 365.8 0.0 2.3e-109 365.3 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 KFR03566.1 - 4.4e-33 113.4 0.4 1.4e-32 111.8 0.1 2.1 2 0 0 2 2 2 1 Mid domain of argonaute ArgoN PF16486.5 KFR03566.1 - 3.6e-30 105.4 0.0 8.9e-30 104.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 KFR03566.1 - 4.2e-28 97.9 1.9 7.2e-28 97.1 1.9 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 KFR03566.1 - 1.3e-22 79.2 0.1 2.7e-22 78.2 0.1 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KFR03566.1 - 3.4e-15 56.1 0.0 7.7e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain Piwi PF02171.17 KFR03567.1 - 7.5e-114 380.0 0.0 1.1e-113 379.5 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 KFR03567.1 - 9.4e-33 112.3 0.4 3.5e-32 110.5 0.1 2.2 2 0 0 2 2 2 1 Mid domain of argonaute PAZ PF02170.22 KFR03567.1 - 8e-29 100.2 0.8 1.3e-28 99.5 0.8 1.3 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 KFR03567.1 - 4.2e-26 92.2 0.0 1.2e-25 90.7 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KFR03567.1 - 1.4e-22 79.1 0.0 3.2e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KFR03567.1 - 7.1e-10 39.1 0.1 2.2e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 Argonaute linker 2 domain Tektin PF03148.14 KFR03568.1 - 2.2e-132 441.4 44.4 2.5e-132 441.3 44.4 1.0 1 0 0 1 1 1 1 Tektin family DUF1664 PF07889.12 KFR03568.1 - 0.00049 20.1 16.5 0.25 11.4 1.0 4.4 3 1 1 4 4 4 2 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 KFR03568.1 - 0.0047 16.5 17.5 0.0047 16.5 17.5 3.1 1 1 1 3 3 3 1 Golgin subfamily A member 5 DUF5082 PF16888.5 KFR03568.1 - 0.0063 16.8 24.5 0.091 13.0 7.3 4.8 3 1 0 3 3 3 2 Domain of unknown function (DUF5082) GAS PF13851.6 KFR03568.1 - 0.0073 15.7 9.4 0.0073 15.7 9.4 3.9 2 2 1 3 3 2 2 Growth-arrest specific micro-tubule binding DUF1192 PF06698.11 KFR03568.1 - 0.024 14.7 1.8 0.024 14.7 1.8 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) CIDR1_gamma PF18562.1 KFR03568.1 - 0.056 13.6 0.4 0.16 12.1 0.4 1.7 1 0 0 1 1 1 0 Cysteine-Rich Interdomain Region 1 gamma LPP PF04728.13 KFR03568.1 - 0.11 12.9 8.4 13 6.3 0.5 4.7 4 0 0 4 4 4 0 Lipoprotein leucine-zipper TM140 PF14985.6 KFR03568.1 - 0.13 11.8 0.1 0.2 11.2 0.1 1.2 1 0 0 1 1 1 0 TM140 protein family Osmo_CC PF08946.10 KFR03568.1 - 0.25 11.6 13.3 9 6.6 1.7 4.0 3 0 0 3 3 3 0 Osmosensory transporter coiled coil TssO PF17561.2 KFR03568.1 - 0.62 10.2 5.9 31 4.6 0.5 3.4 3 0 0 3 3 3 0 Type VI secretion system, TssO DUF948 PF06103.11 KFR03568.1 - 2.2 8.6 11.5 2.4 8.5 0.8 4.3 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Prefoldin PF02996.17 KFR03568.1 - 5.7 6.9 17.5 13 5.7 2.5 4.5 4 0 0 4 4 4 0 Prefoldin subunit Bap31_Bap29_C PF18035.1 KFR03568.1 - 7.3 6.7 9.9 22 5.2 0.3 4.0 3 0 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain OmpH PF03938.14 KFR03568.1 - 9.5 6.6 31.7 3.9 7.8 8.8 4.6 2 2 1 3 3 3 0 Outer membrane protein (OmpH-like) ADP_ribosyl_GH PF03747.14 KFR03569.1 - 1.3e-56 192.5 0.0 1.5e-56 192.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase CxC7 PF18866.1 KFR03569.1 - 0.47 10.6 1.4 1.1 9.5 0.2 2.2 2 1 0 2 2 2 0 CxC7 like cysteine cluster associated with KDZ transposases TRAPP PF04051.16 KFR03570.1 - 3.2e-37 127.5 0.0 3.6e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Glyco_hydro_3_C PF01915.22 KFR03571.1 - 1.2e-18 67.8 0.0 1.5e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KFR03572.1 - 1.6e-15 56.9 1.4 2.9e-15 56.1 1.4 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain THRAP3_BCLAF1 PF15440.6 KFR03573.1 - 1e-201 672.5 112.2 1e-201 672.5 112.2 2.3 2 0 0 2 2 2 1 THRAP3/BCLAF1 family FAM176 PF14851.6 KFR03574.1 - 1.1e-48 164.6 0.0 1.3e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 FAM176 family NUP50 PF08911.11 KFR03574.1 - 1.2 9.8 3.6 2.4 8.9 3.6 1.4 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) Pkinase PF00069.25 KFR03575.1 - 2.1e-37 128.9 0.0 3.2e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR03575.1 - 1.5e-20 73.6 0.0 2.5e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR03575.1 - 2.9e-05 23.6 1.1 0.00055 19.3 0.1 2.5 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFR03575.1 - 0.00069 18.5 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFR03575.1 - 0.0064 15.5 0.7 0.015 14.2 0.7 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFR03575.1 - 0.033 13.6 0.1 0.061 12.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LSM PF01423.22 KFR03576.1 - 5.1e-13 48.5 0.2 6.8e-13 48.1 0.2 1.2 1 0 0 1 1 1 1 LSM domain Oscp1 PF10188.9 KFR03577.1 - 5.8e-70 234.9 2.6 8.3e-70 234.4 2.6 1.1 1 0 0 1 1 1 1 Organic solute transport protein 1 ANF_receptor PF01094.28 KFR03578.1 - 7e-72 242.5 0.0 9.3e-72 242.1 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 KFR03578.1 - 6.3e-54 181.9 0.1 1e-53 181.2 0.1 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFR03578.1 - 2.6e-46 156.5 0.0 1.1e-45 154.5 0.0 2.1 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFR03578.1 - 1.9e-19 70.0 0.0 4.3e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.6 KFR03578.1 - 6.9e-05 22.7 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein RNase_Zc3h12a PF11977.8 KFR03579.1 - 7.1e-55 185.1 0.0 1e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Regnase_1_C PF18561.1 KFR03579.1 - 1.2e-25 89.0 0.1 2.2e-25 88.1 0.1 1.5 1 0 0 1 1 1 1 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain zf-CCCH_4 PF18044.1 KFR03579.1 - 4.8e-05 23.0 5.5 8.3e-05 22.3 3.5 2.3 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 KFR03579.1 - 0.026 14.4 7.1 0.054 13.4 2.7 3.1 2 1 1 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KFR03579.1 - 0.03 14.8 6.0 0.088 13.3 6.0 1.9 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger FAM220 PF15487.6 KFR03579.1 - 0.2 11.3 1.8 0.34 10.5 1.8 1.3 1 0 0 1 1 1 0 FAM220 family zf_CCCH_4 PF18345.1 KFR03579.1 - 3.9 7.7 10.2 4.3 7.5 1.8 3.2 2 1 1 3 3 3 0 Zinc finger domain NuA4 PF09340.10 KFR03580.1 - 0.062 13.2 2.4 0.12 12.3 0.2 2.2 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 FHA PF00498.26 KFR03581.1 - 7.8e-20 71.0 0.7 3.1e-19 69.1 0.0 2.1 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KFR03581.1 - 1.9e-05 24.9 0.0 0.0009 19.5 0.0 2.5 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Ax_dynein_light PF10211.9 KFR03582.1 - 1.4e-63 214.3 15.6 1.5e-63 214.1 15.6 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain UPF0242 PF06785.11 KFR03582.1 - 0.098 12.8 10.6 0.12 12.5 10.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PRKG1_interact PF15898.5 KFR03582.1 - 0.13 13.2 13.6 0.19 12.7 13.6 1.3 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Presenilin PF01080.17 KFR03582.1 - 1.3 7.7 4.5 1.5 7.5 4.5 1.0 1 0 0 1 1 1 0 Presenilin bZIP_2 PF07716.15 KFR03582.1 - 2.1 8.5 18.2 0.13 12.4 6.2 2.4 1 1 1 2 2 2 0 Basic region leucine zipper Mto2_bdg PF12808.7 KFR03582.1 - 7.2 7.0 18.3 0.44 10.9 4.0 2.8 2 1 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region NGP1NT PF08153.12 KFR03583.1 - 2.1e-48 163.8 1.1 6.3e-48 162.2 1.1 1.9 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KFR03583.1 - 3.3e-17 62.6 0.2 8.9e-13 48.3 0.0 3.5 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KFR03583.1 - 2.4e-05 23.9 0.1 0.00012 21.6 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFR03583.1 - 0.00014 21.9 0.0 0.00058 19.8 0.0 2.1 1 1 0 1 1 1 1 RsgA GTPase Arf PF00025.21 KFR03583.1 - 0.0021 17.5 0.2 0.3 10.5 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.23 KFR03583.1 - 0.2 11.7 9.9 0.43 10.6 2.5 4.6 2 1 1 3 3 3 0 Dynamin family Furin-like_2 PF15913.5 KFR03584.1 - 3.7e-49 165.4 22.2 3.7e-49 165.4 22.2 2.0 2 0 0 2 2 2 1 Furin-like repeat, cysteine-rich TSP_1 PF00090.19 KFR03584.1 - 0.00028 21.1 4.5 0.00028 21.1 4.5 3.8 3 1 1 4 4 4 1 Thrombospondin type 1 domain CK2S PF15011.6 KFR03585.1 - 1.7e-10 41.0 0.1 2.6e-10 40.4 0.1 1.3 1 0 0 1 1 1 1 Casein Kinase 2 substrate Scm3 PF10384.9 KFR03585.1 - 0.076 12.8 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Centromere protein Scm3 Borealin PF10512.9 KFR03586.1 - 2.5e-28 98.5 0.0 3e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Cell division cycle-associated protein 8 Pkinase_Tyr PF07714.17 KFR03587.1 - 3.7e-77 259.1 0.0 7e-77 258.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.19 KFR03587.1 - 2.7e-69 232.8 0.0 5.1e-69 231.9 0.0 1.5 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.25 KFR03587.1 - 1.4e-32 113.1 0.0 4.3e-32 111.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain fn3 PF00041.21 KFR03587.1 - 1e-18 67.4 8.7 6e-10 39.3 0.0 3.9 3 2 0 3 3 3 2 Fibronectin type III domain EphA2_TM PF14575.6 KFR03587.1 - 1.2e-17 64.5 0.0 2.8e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SAM_1 PF00536.30 KFR03587.1 - 1.4e-17 63.9 0.0 3.3e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFR03587.1 - 2.5e-16 59.5 0.0 9.2e-16 57.7 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Pur_ac_phosph_N PF16656.5 KFR03587.1 - 0.00013 22.4 0.9 0.0089 16.6 1.4 2.5 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Ephrin_rec_like PF07699.13 KFR03587.1 - 0.003 17.3 3.4 0.003 17.3 3.4 2.6 2 1 0 2 2 2 1 Putative ephrin-receptor like Interfer-bind PF09294.10 KFR03587.1 - 0.014 15.7 0.6 0.07 13.4 0.6 2.1 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III TMEM154 PF15102.6 KFR03587.1 - 0.16 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Sua5_yciO_yrdC PF01300.18 KFR03588.1 - 9.4e-47 158.8 0.0 1.1e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 Telomere recombination zf-C2H2 PF00096.26 KFR03589.1 - 6.3e-28 95.6 40.3 7.9e-05 22.9 1.3 6.6 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFR03589.1 - 8.1e-26 89.3 44.7 1.5e-07 31.5 0.5 7.4 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR03589.1 - 1.1e-17 63.2 37.3 0.0077 17.0 0.9 7.0 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFR03589.1 - 2.5e-10 40.5 22.3 0.00019 21.6 5.0 4.1 1 1 1 3 3 3 3 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KFR03589.1 - 5.2e-05 23.4 26.5 0.03 14.6 1.8 6.6 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFR03589.1 - 0.0053 16.7 1.2 0.0053 16.7 1.2 5.6 6 0 0 6 6 6 3 C2H2-type zinc finger Marek_A PF02124.15 KFR03589.1 - 0.0088 15.9 2.1 0.34 10.7 0.2 2.7 2 1 1 3 3 3 1 Marek's disease glycoprotein A zf-C2H2_aberr PF17017.5 KFR03589.1 - 0.39 10.8 19.7 3.6 7.7 1.5 5.2 1 1 4 5 5 5 0 Aberrant zinc-finger RhoGAP PF00620.27 KFR03590.1 - 3.5e-26 91.8 0.0 6.9e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 KFR03590.1 - 8.3e-17 61.5 0.0 1.2e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3449 PF11931.8 KFR03591.1 - 4.4e-78 261.3 5.0 6.3e-78 260.8 4.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) Telomere_Sde2_2 PF13297.6 KFR03591.1 - 3.3e-25 87.5 1.3 6.9e-25 86.5 1.3 1.6 1 0 0 1 1 1 1 Telomere stability C-terminal SF3A3 PF16837.5 KFR03591.1 - 1.8e-23 82.8 6.9 6.3e-23 81.1 6.9 2.0 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KFR03591.1 - 8e-16 57.6 1.2 1.6e-15 56.6 1.2 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain LIM PF00412.22 KFR03592.1 - 5.6e-49 164.2 70.3 2.4e-12 46.9 5.6 5.1 5 0 0 5 5 5 5 LIM domain Utp11 PF03998.13 KFR03593.1 - 8.6e-66 222.3 22.3 9.6e-66 222.2 22.3 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 KFR03593.1 - 0.023 14.0 1.1 0.041 13.2 0.4 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Pou PF00157.17 KFR03594.1 - 9e-38 128.1 0.3 1.6e-37 127.3 0.3 1.4 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KFR03594.1 - 3.8e-19 68.3 0.1 8.9e-19 67.1 0.1 1.6 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 KFR03594.1 - 0.00012 22.3 0.0 0.023 15.1 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain Homeobox_KN PF05920.11 KFR03594.1 - 0.0064 16.4 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain DUF521 PF04412.13 KFR03594.1 - 0.17 10.6 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Gtr1_RagA PF04670.12 KFR03595.1 - 6.9e-63 212.1 2.4 8.9e-63 211.7 2.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KFR03595.1 - 0.024 14.1 0.1 0.037 13.5 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Roc PF08477.13 KFR03595.1 - 0.037 14.2 0.0 0.068 13.4 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase TSC22 PF01166.18 KFR03596.1 - 0.0026 18.0 0.9 0.0038 17.5 0.9 1.3 1 0 0 1 1 1 1 TSC-22/dip/bun family ZapB PF06005.12 KFR03596.1 - 0.0055 17.1 1.6 0.0092 16.4 1.6 1.3 1 0 0 1 1 1 1 Cell division protein ZapB HALZ PF02183.18 KFR03596.1 - 0.019 15.1 2.1 0.065 13.5 2.1 1.9 1 1 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.15 KFR03596.1 - 0.068 12.9 0.9 0.089 12.6 0.9 1.2 1 0 0 1 1 1 0 Septum formation initiator Connexin PF00029.19 KFR03597.1 - 2.2e-97 325.4 0.5 2.5e-97 325.3 0.5 1.0 1 0 0 1 1 1 1 Connexin YTH PF04146.15 KFR03598.1 - 1.2e-41 142.5 0.5 4.7e-41 140.5 0.5 1.9 1 1 0 1 1 1 1 YT521-B-like domain SAND PF01342.21 KFR03599.1 - 1.1e-23 82.7 0.2 2e-23 81.9 0.2 1.5 1 0 0 1 1 1 1 SAND domain CUB PF00431.20 KFR03600.1 - 9e-14 51.8 0.0 9.9e-14 51.6 0.0 1.0 1 0 0 1 1 1 1 CUB domain TFIID_20kDa PF03847.13 KFR03601.1 - 3.6e-36 123.5 2.8 5e-36 123.0 2.8 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KFR03601.1 - 6.6e-06 26.3 0.2 1e-05 25.7 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFR03601.1 - 3.2e-05 24.3 1.1 3.6e-05 24.1 0.1 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KFR03601.1 - 8.8e-05 22.6 0.2 0.00019 21.5 0.1 1.6 1 1 1 2 2 2 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KFR03601.1 - 0.0056 16.8 0.1 0.0096 16.0 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF4 PF05236.14 KFR03601.1 - 0.0088 15.8 0.0 0.0092 15.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Ras PF00071.22 KFR03602.1 - 2.9e-26 92.0 0.0 3.3e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR03602.1 - 4.9e-05 23.5 0.0 0.00018 21.7 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Trnau1ap PF17654.1 KFR03603.1 - 2.9e-42 143.7 20.5 3.9e-42 143.3 20.5 1.2 1 0 0 1 1 1 1 Selenocysteine tRNA 1 associated proteins RRM_1 PF00076.22 KFR03603.1 - 5.2e-13 48.6 0.0 7.7e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cys_knot PF00007.22 KFR03604.1 - 5.9e-13 49.0 9.2 5.9e-13 49.0 9.2 3.7 4 0 0 4 4 4 1 Cystine-knot domain IGFBP PF00219.18 KFR03604.1 - 1.7e-10 41.4 21.9 1.7e-10 41.4 21.9 5.9 3 2 1 4 4 4 1 Insulin-like growth factor binding protein VWC PF00093.18 KFR03604.1 - 4.4e-08 33.3 10.3 4.4e-08 33.3 10.3 5.4 4 3 0 4 4 4 1 von Willebrand factor type C domain TSP_1 PF00090.19 KFR03604.1 - 1e-06 28.8 6.6 1.6e-05 25.0 6.6 3.2 1 0 0 1 1 1 1 Thrombospondin type 1 domain 4_1_CTD PF05902.13 KFR03605.1 - 1.1e-48 163.7 13.8 3e-48 162.3 13.8 1.8 1 0 0 1 1 1 1 4.1 protein C-terminal domain (CTD) FERM_C PF09380.10 KFR03605.1 - 3e-25 88.4 0.0 8e-25 87.1 0.0 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain SAB PF04382.13 KFR03605.1 - 3.4e-23 81.5 2.9 1.1e-22 79.9 2.9 2.0 1 0 0 1 1 1 1 SAB domain FERM_M PF00373.18 KFR03605.1 - 4.7e-20 72.2 1.1 8.7e-20 71.3 0.1 2.0 2 0 0 2 2 2 1 FERM central domain FA PF08736.11 KFR03605.1 - 3.7e-19 68.5 3.3 1.2e-18 66.9 3.3 2.0 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_N PF09379.10 KFR03605.1 - 1.1e-17 63.7 0.2 3.7e-17 62.0 0.1 1.9 2 0 0 2 2 2 1 FERM N-terminal domain Wound_ind PF08186.11 KFR03605.1 - 0.09 13.2 0.2 0.09 13.2 0.2 2.0 2 0 0 2 2 2 0 Wound-inducible basic protein family MBT PF02820.18 KFR03606.1 - 8.5e-94 307.9 1.0 4e-30 104.0 0.0 3.2 3 0 0 3 3 3 3 mbt repeat zf-C2HC PF01530.18 KFR03606.1 - 2.1e-11 43.8 9.8 3.7e-11 43.0 9.8 1.4 1 0 0 1 1 1 1 Zinc finger, C2HC type Tudor-knot PF11717.8 KFR03606.1 - 0.0039 17.1 2.2 0.057 13.3 0.5 2.5 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain RRM_1 PF00076.22 KFR03608.1 - 6.9e-22 77.1 0.0 1.2e-13 50.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFR03608.1 - 1.4e-05 25.0 0.0 9.8e-05 22.3 0.0 2.5 1 0 0 1 1 1 1 RNA binding motif ADH_zinc_N PF00107.26 KFR03609.1 - 3.6e-21 75.5 0.0 5.4e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFR03609.1 - 1.2e-08 34.8 0.0 3.4e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFR03609.1 - 2.9e-07 31.6 0.0 5.6e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF4265 PF14085.6 KFR03609.1 - 0.016 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) Y_phosphatase PF00102.27 KFR03610.1 - 6.2e-98 327.1 0.3 4.9e-78 261.9 0.1 2.6 2 0 0 2 2 2 2 Protein-tyrosine phosphatase MAM PF00629.23 KFR03610.1 - 5.8e-36 123.8 0.0 1.5e-35 122.5 0.0 1.8 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu fn3 PF00041.21 KFR03610.1 - 2.4e-31 107.9 1.2 3.4e-12 46.5 0.1 4.9 5 0 0 5 5 5 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFR03610.1 - 0.00027 21.4 0.0 0.18 12.4 0.0 3.8 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain ig PF00047.25 KFR03610.1 - 0.0037 17.4 0.0 0.0092 16.1 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFR03610.1 - 0.0049 17.2 0.0 0.016 15.5 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFR03610.1 - 0.0059 16.7 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR03610.1 - 0.006 17.2 0.0 0.02 15.5 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain Y_phosphatase3 PF13350.6 KFR03610.1 - 0.014 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 KFR03610.1 - 0.036 13.9 0.1 0.083 12.7 0.1 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFR03610.1 - 0.041 14.0 0.0 0.084 13.0 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate PsbX PF06596.11 KFR03610.1 - 0.95 9.5 5.3 1.9 8.5 5.3 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) Ribosomal_S6e PF01092.19 KFR03640.1 - 4.2e-64 214.1 1.5 9.5e-64 213.0 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S6e DUF4574 PF15141.6 KFR03640.1 - 1.2 9.0 5.8 2.3 8.2 5.8 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Ceramidase PF05875.12 KFR03641.1 - 2.2e-40 138.8 12.2 2.5e-40 138.6 12.2 1.0 1 0 0 1 1 1 1 Ceramidase Na_Ca_ex PF01699.24 KFR03642.1 - 5.5e-59 198.5 54.3 7.2e-31 107.2 22.6 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein AHD PF17793.1 KFR03644.1 - 1.8e-27 94.9 1.4 3.7e-27 93.9 1.4 1.5 1 0 0 1 1 1 1 ANC1 homology domain (AHD) YEATS PF03366.16 KFR03644.1 - 3.5e-08 33.3 0.0 6.9e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 YEATS family BET PF17035.5 KFR03644.1 - 0.043 14.0 0.2 0.1 12.8 0.2 1.7 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation Focadhesin PF11229.8 KFR03645.1 - 0 1027.5 12.0 0 1026.9 12.0 1.3 1 0 0 1 1 1 1 Focadhesin DUF3730 PF12530.8 KFR03645.1 - 5.4e-71 238.8 1.2 5.4e-71 238.8 1.2 3.7 4 0 0 4 4 4 1 Protein of unknown function (DUF3730) NESP55 PF06390.12 KFR03645.1 - 0.016 14.8 2.5 0.02 14.5 0.6 1.9 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) HEAT PF02985.22 KFR03645.1 - 3.3 8.2 5.7 22 5.6 0.3 4.7 5 0 0 5 5 5 0 HEAT repeat PTPLA PF04387.14 KFR03646.1 - 1.7e-37 128.7 10.5 2.6e-37 128.1 10.5 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Interferon PF00143.19 KFR03647.1 - 6.4e-48 163.0 9.6 7.4e-48 162.7 9.6 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain GBP PF02263.19 KFR03647.1 - 2 7.6 7.3 4.3 6.5 2.6 2.1 1 1 1 2 2 2 0 Guanylate-binding protein, N-terminal domain Tubulin_C PF03953.17 KFR03648.1 - 8.6e-37 126.1 0.0 1.3e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 KFR03648.1 - 3.5e-33 115.5 0.0 5.3e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 KFR03648.1 - 0.00061 19.5 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain LMBR1 PF04791.16 KFR03649.1 - 1.3e-83 281.7 21.4 2.9e-50 171.7 12.1 2.0 1 1 1 2 2 2 2 LMBR1-like membrane protein SH PF01445.17 KFR03649.1 - 0.031 14.2 0.6 0.29 11.1 0.0 2.9 3 0 0 3 3 3 0 Viral small hydrophobic protein Ras PF00071.22 KFR03650.1 - 6.1e-22 78.0 0.0 6.9e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR03650.1 - 0.0047 17.1 0.0 0.0083 16.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KFR03650.1 - 0.045 13.6 0.0 0.052 13.5 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase PHD PF00628.29 KFR03651.1 - 5.1e-20 71.1 29.2 8.9e-11 41.5 11.4 2.5 1 1 1 2 2 2 2 PHD-finger C1_1 PF00130.22 KFR03651.1 - 0.0028 17.5 5.5 0.0028 17.5 5.5 4.3 1 1 3 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 KFR03651.1 - 0.015 14.9 20.2 0.14 11.8 4.0 3.0 2 2 1 3 3 3 0 PHD/FYVE-zinc-finger like domain DUF2318 PF10080.9 KFR03651.1 - 0.02 15.0 2.5 0.02 15.0 2.5 2.5 2 1 0 3 3 3 0 Predicted membrane protein (DUF2318) PLA2_B PF01735.18 KFR03651.1 - 0.93 7.8 3.0 1.5 7.2 0.2 2.0 2 0 0 2 2 2 0 Lysophospholipase catalytic domain Aldo_ket_red PF00248.21 KFR03652.1 - 2.8e-52 177.8 0.0 4.1e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family His_Phos_1 PF00300.22 KFR03653.1 - 8.4e-34 117.0 0.0 3.8e-26 92.0 0.0 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Caldesmon PF02029.15 KFR03654.1 - 1.4e-169 565.0 188.6 2.2e-135 452.3 121.9 2.1 1 1 1 2 2 2 2 Caldesmon Aldo_ket_red PF00248.21 KFR03655.1 - 2.1e-54 184.7 0.1 4e-54 183.8 0.1 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family Ras PF00071.22 KFR03656.1 - 2.3e-26 92.4 0.0 2.5e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR03656.1 - 8.6e-05 22.8 0.0 0.00011 22.4 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR03656.1 - 0.0045 16.5 0.0 0.0054 16.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Y_phosphatase PF00102.27 KFR03657.1 - 5.4e-84 281.4 1.7 1.3e-83 280.2 1.7 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase fn3 PF00041.21 KFR03657.1 - 1.8e-29 101.9 18.3 2.4e-08 34.2 0.6 6.3 6 0 0 6 6 6 5 Fibronectin type III domain Y_phosphatase3 PF13350.6 KFR03657.1 - 7.3e-05 22.8 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KFR03657.1 - 0.00015 21.6 0.0 0.0004 20.2 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFR03657.1 - 0.0007 19.7 0.0 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate Pur_ac_phosph_N PF16656.5 KFR03657.1 - 0.0032 18.0 12.2 1.2 9.8 0.4 4.6 4 0 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain SIT PF15330.6 KFR03657.1 - 8.3 6.9 6.3 1.2e+02 3.1 1.2 3.8 4 0 0 4 4 4 0 SHP2-interacting transmembrane adaptor protein, SIT PTB PF08416.13 KFR03658.1 - 5.1e-53 178.7 1.6 9.6e-53 177.8 1.6 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SAM_3 PF18016.1 KFR03658.1 - 7.1e-23 80.2 0.0 1.7e-22 79.0 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 KFR03658.1 - 9.7e-10 37.9 0.1 2.4e-09 36.6 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFR03658.1 - 3.2e-06 26.9 0.0 7.9e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PID PF00640.23 KFR03658.1 - 1.8e-05 24.8 1.7 2.6e-05 24.3 0.3 2.0 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) SH3_2 PF07653.17 KFR03658.1 - 1.8e-05 24.3 0.0 3.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFR03658.1 - 0.0011 19.2 0.1 0.0028 17.9 0.1 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_10 PF17902.1 KFR03658.1 - 0.0086 16.1 0.2 0.03 14.4 0.0 2.0 2 0 0 2 2 2 1 SH3 domain WD40 PF00400.32 KFR03659.1 - 7.5e-31 105.7 2.2 5.5e-10 39.7 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR03659.1 - 2.1e-08 34.3 0.0 0.14 12.5 0.0 4.2 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFR03659.1 - 0.006 15.6 0.0 0.19 10.7 0.0 2.5 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Me-amine-dh_H PF06433.11 KFR03659.1 - 0.0085 15.0 0.2 0.29 9.9 0.1 2.8 2 2 1 3 3 3 1 Methylamine dehydrogenase heavy chain (MADH) WD40_like PF17005.5 KFR03659.1 - 0.024 14.0 0.0 0.25 10.6 0.1 2.2 1 1 1 3 3 3 0 WD40-like domain Cytochrom_D1 PF02239.16 KFR03659.1 - 0.027 13.0 0.1 0.71 8.3 0.0 2.0 1 1 1 2 2 2 0 Cytochrome D1 heme domain Frtz PF11768.8 KFR03659.1 - 0.056 11.8 0.0 4.5 5.5 0.0 2.4 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz DeoC PF01791.9 KFR03660.1 - 1.3e-26 93.7 0.0 1.7e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase SH3_6 PF12913.7 KFR03660.1 - 0.14 11.7 0.8 0.26 10.9 0.8 1.4 1 0 0 1 1 1 0 SH3 domain (SH3b1 type) PTR2 PF00854.21 KFR03661.1 - 2.8e-40 138.4 10.1 3.7e-40 138.0 10.1 1.1 1 0 0 1 1 1 1 POT family MAPEG PF01124.18 KFR03662.1 - 4.3e-25 88.1 0.3 4.9e-25 87.9 0.3 1.0 1 0 0 1 1 1 1 MAPEG family Anoctamin PF04547.12 KFR03662.1 - 0.051 12.4 0.0 0.063 12.1 0.0 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel LIM PF00412.22 KFR03663.1 - 1.4e-30 105.2 22.1 3.8e-15 55.9 8.1 2.0 2 0 0 2 2 2 2 LIM domain Ras PF00071.22 KFR03664.1 - 3.1e-19 69.1 0.0 4.2e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Ras family PI3_PI4_kinase PF00454.27 KFR03665.1 - 2.7e-50 171.5 0.8 9e-49 166.5 0.8 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KFR03665.1 - 4.3e-26 91.5 4.3 4.3e-26 91.5 4.3 2.8 4 0 0 4 4 4 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PX PF00787.24 KFR03665.1 - 7e-12 45.3 3.6 9.7e-12 44.9 1.3 2.5 3 0 0 3 3 3 1 PX domain C2 PF00168.30 KFR03665.1 - 5.9e-08 32.9 0.0 2.5e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 C2 domain PI3K_rbd PF00794.18 KFR03665.1 - 1e-05 25.7 1.0 5.2e-05 23.4 0.0 2.7 3 0 0 3 3 3 1 PI3-kinase family, ras-binding domain DUF4135 PF13575.6 KFR03665.1 - 0.00053 19.4 0.0 0.00094 18.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) PI-PLC-X PF00388.19 KFR03666.1 - 2.4e-62 208.8 0.0 3.7e-62 208.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFR03666.1 - 1.1e-42 145.0 0.2 2.2e-42 144.0 0.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 KFR03666.1 - 4.2e-21 75.2 0.2 1.1e-20 73.9 0.2 1.8 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 KFR03666.1 - 2.4e-14 53.5 0.0 6.2e-14 52.1 0.0 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.6 KFR03666.1 - 0.0039 17.6 0.3 0.043 14.3 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain pair GreA_GreB PF01272.19 KFR03666.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Transcription elongation factor, GreA/GreB, C-term F-actin_cap_A PF01267.17 KFR03667.1 - 2.6e-72 243.5 0.0 2.9e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit DUF553 PF04473.12 KFR03667.1 - 0.0025 17.4 0.2 0.0037 16.8 0.2 1.2 1 0 0 1 1 1 1 Transglutaminase-like domain PH PF00169.29 KFR03668.1 - 2.7e-19 69.6 0.6 7.5e-18 65.0 0.1 3.1 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KFR03668.1 - 0.00063 20.1 5.5 0.017 15.5 5.5 3.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KFR03668.1 - 0.003 17.6 0.0 0.0078 16.3 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KFR03668.1 - 0.055 13.8 0.2 1.1 9.6 0.2 2.8 1 1 0 1 1 1 0 Pleckstrin homology domain PH_8 PF15409.6 KFR03668.1 - 0.085 13.2 0.0 0.26 11.6 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain zf-C2H2 PF00096.26 KFR03669.1 - 6.7e-08 32.6 14.2 0.13 12.7 0.0 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR03669.1 - 1.5e-05 25.5 13.9 0.11 13.3 0.1 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFR03669.1 - 0.00044 20.5 0.0 0.00044 20.5 0.0 3.3 4 0 0 4 4 4 1 Zinc-finger double domain Zn-C2H2_12 PF18112.1 KFR03669.1 - 0.0051 17.3 0.0 0.66 10.5 0.0 2.6 2 0 0 2 2 2 1 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_11 PF16622.5 KFR03669.1 - 0.011 15.5 13.2 0.77 9.6 0.0 3.6 3 0 0 3 3 3 0 zinc-finger C2H2-type DUF4764 PF15961.5 KFR03669.1 - 0.014 14.2 0.4 0.017 13.8 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4764) zf-C2H2_aberr PF17017.5 KFR03669.1 - 0.19 11.9 2.1 3.1 7.9 0.0 2.4 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_8 PF15909.5 KFR03669.1 - 0.24 11.7 3.3 3.3 8.1 0.3 2.4 1 1 3 4 4 4 0 C2H2-type zinc ribbon PDEase_I PF00233.19 KFR03671.1 - 3.6e-65 220.0 0.3 1.7e-60 204.7 0.0 2.4 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase OATP PF03137.20 KFR03672.1 - 7.3e-173 575.8 11.4 9.8e-173 575.3 11.4 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFR03672.1 - 7.2e-24 84.4 15.7 1e-18 67.4 1.1 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily Kazal_2 PF07648.15 KFR03672.1 - 2.9e-11 43.3 7.9 7.7e-11 42.0 7.9 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFR03672.1 - 6.3e-05 22.9 3.2 0.00017 21.5 3.2 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain OATP PF03137.20 KFR03673.1 - 3.5e-169 563.6 25.1 4.2e-169 563.3 25.1 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFR03673.1 - 6.9e-21 74.5 27.6 1.4e-19 70.2 19.5 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.15 KFR03673.1 - 1.6e-10 40.9 11.9 1.8e-10 40.7 10.0 2.1 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFR03673.1 - 0.0066 16.4 5.9 0.017 15.1 5.9 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain TauE PF01925.19 KFR03673.1 - 0.75 9.4 15.9 0.26 10.9 1.5 3.8 4 0 0 4 4 4 0 Sulfite exporter TauE/SafE OATP PF03137.20 KFR03674.1 - 2.6e-164 547.6 18.4 2.9e-164 547.4 18.4 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFR03674.1 - 3.2e-22 78.9 27.8 1.1e-19 70.6 10.6 2.9 3 0 0 3 3 3 2 Major Facilitator Superfamily Kazal_2 PF07648.15 KFR03674.1 - 1.5e-11 44.2 6.7 3.9e-11 42.9 6.7 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFR03674.1 - 0.0024 17.8 5.0 0.0059 16.6 5.0 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain TauE PF01925.19 KFR03674.1 - 5.8 6.5 22.3 0.28 10.8 1.8 3.7 4 0 0 4 4 4 0 Sulfite exporter TauE/SafE OATP PF03137.20 KFR03675.1 - 1.5e-169 564.8 17.5 1.7e-169 564.6 17.5 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFR03675.1 - 1.7e-26 93.0 18.8 8.4e-25 87.4 14.0 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.15 KFR03675.1 - 2.3e-11 43.6 6.0 4.7e-11 42.6 6.0 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFR03675.1 - 3.6e-05 23.7 4.1 7.8e-05 22.6 4.1 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain SBF PF01758.16 KFR03675.1 - 0.001 18.8 0.6 0.1 12.2 0.2 2.7 2 0 0 2 2 2 1 Sodium Bile acid symporter family Calc_CGRP_IAPP PF00214.19 KFR03676.1 - 2.9e-29 101.9 0.1 3.3e-29 101.7 0.1 1.0 1 0 0 1 1 1 1 Calcitonin / CGRP / IAPP family Fe-S_biosyn PF01521.20 KFR03748.1 - 1.5e-19 70.2 0.0 1.7e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis RRM_1 PF00076.22 KFR03749.1 - 1.2e-16 60.2 0.1 9.2e-07 28.6 0.3 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinesin PF00225.23 KFR03765.1 - 5.5e-51 173.5 1.8 5.5e-51 173.5 1.8 1.6 2 0 0 2 2 2 1 Kinesin motor domain SAM_1 PF00536.30 KFR03765.1 - 0.0046 17.4 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFR03765.1 - 0.058 13.5 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) NUDIX PF00293.28 KFR03766.1 - 6.1e-20 71.6 0.2 7.3e-20 71.4 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain I-set PF07679.16 KFR03766.1 - 0.065 13.3 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 Immunoglobulin I-set domain DUF2873 PF11395.8 KFR03767.1 - 0.017 15.0 0.2 0.021 14.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2873) Ricin_B_lectin PF00652.22 KFR03768.1 - 2.2e-09 37.6 5.6 2.5e-09 37.4 3.8 1.9 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 KFR03768.1 - 3.9e-05 23.3 0.1 6.5e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Cytolethal distending toxin A/C domain Pkinase PF00069.25 KFR03791.1 - 1.5e-05 24.6 0.0 1.6e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain zf-Nse PF11789.8 KFR03792.1 - 1.5e-19 69.5 2.5 2.6e-19 68.8 2.5 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KFR03792.1 - 2.6e-08 33.7 0.2 6.4e-08 32.5 0.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 KFR03792.1 - 0.00023 20.6 3.1 0.00045 19.7 3.1 1.6 1 1 0 1 1 1 1 Rtf2 RING-finger zf-MIZ PF02891.20 KFR03792.1 - 0.001 18.8 1.9 0.0025 17.5 1.9 1.8 1 1 0 1 1 1 1 MIZ/SP-RING zinc finger U-box PF04564.15 KFR03792.1 - 0.0019 18.3 0.1 0.0055 16.8 0.1 1.8 1 1 0 1 1 1 1 U-box domain HalX PF08663.10 KFR03792.1 - 0.0041 17.4 4.2 0.049 14.0 1.7 2.5 1 1 1 2 2 2 1 HalX domain Transferase PF02458.15 KFR03792.1 - 0.029 13.0 0.6 0.041 12.5 0.6 1.2 1 0 0 1 1 1 0 Transferase family zf-C3HC4_2 PF13923.6 KFR03792.1 - 0.049 13.5 0.2 0.049 13.5 0.2 2.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFR03792.1 - 0.1 12.9 0.7 0.1 12.9 0.7 1.9 2 0 0 2 2 2 0 Ring finger domain ParB PF08775.10 KFR03792.1 - 2.1 8.8 10.2 7 7.1 1.1 2.2 1 1 1 2 2 2 0 ParB family zf-C3HC4 PF00097.25 KFR03792.1 - 3.9 7.4 6.3 0.42 10.5 0.6 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Strumpellin PF10266.9 KFR03793.1 - 0 1659.6 19.4 0 1659.5 19.4 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin HTH_43 PF09904.9 KFR03793.1 - 0.07 13.1 0.1 0.3 11.0 0.1 2.1 2 0 0 2 2 2 0 Winged helix-turn helix EF-hand_9 PF14658.6 KFR03793.1 - 0.15 12.4 0.0 0.73 10.2 0.0 2.3 1 0 0 1 1 1 0 EF-hand domain DUF3502 PF12010.8 KFR03793.1 - 1.9 9.1 6.6 14 6.3 0.3 4.3 3 2 1 4 4 4 0 Domain of unknown function (DUF3502) SE PF08491.10 KFR03794.1 - 5.8e-111 370.0 0.1 7.5e-111 369.6 0.1 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KFR03794.1 - 1e-20 74.3 0.0 1.4e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFR03794.1 - 2.9e-10 40.3 0.0 0.00038 20.1 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFR03794.1 - 0.00017 22.1 0.1 0.00051 20.5 0.1 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFR03794.1 - 0.00022 20.4 0.2 0.4 9.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KFR03794.1 - 0.00024 21.3 0.1 0.00054 20.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 KFR03794.1 - 0.0021 18.3 0.1 0.0043 17.3 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain GMC_oxred_N PF00732.19 KFR03794.1 - 0.0079 15.6 0.0 3.5 6.9 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase 3HCDH_N PF02737.18 KFR03794.1 - 0.0082 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KFR03794.1 - 0.0082 15.4 0.0 0.017 14.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFR03794.1 - 0.014 14.6 0.0 0.15 11.2 0.0 2.1 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.16 KFR03794.1 - 0.022 14.4 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KFR03794.1 - 0.03 14.3 0.0 0.071 13.1 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 KFR03794.1 - 0.032 14.5 0.0 0.065 13.5 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Trp_halogenase PF04820.14 KFR03794.1 - 0.044 12.6 0.2 2.8 6.7 0.1 2.6 2 1 1 3 3 3 0 Tryptophan halogenase Shikimate_DH PF01488.20 KFR03794.1 - 0.06 13.4 0.0 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 KFR03794.1 - 0.062 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KFR03794.1 - 0.18 12.4 0.0 0.54 10.9 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IMD PF08397.11 KFR03795.1 - 1.2e-79 266.7 5.1 1.6e-79 266.4 5.1 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain Gp58 PF07902.11 KFR03795.1 - 0.035 12.4 0.8 0.046 12.0 0.8 1.1 1 0 0 1 1 1 0 gp58-like protein CK2S PF15011.6 KFR03795.1 - 0.11 12.4 2.8 0.2 11.5 1.7 2.1 2 0 0 2 2 2 0 Casein Kinase 2 substrate OmpH PF03938.14 KFR03795.1 - 0.41 11.0 8.6 0.86 9.9 8.6 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Complex1_LYR PF05347.15 KFR03797.1 - 2.8e-13 49.7 1.1 2.8e-13 49.7 1.1 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFR03797.1 - 0.0014 19.3 0.3 0.0029 18.3 0.3 1.5 1 0 0 1 1 1 1 Complex1_LYR-like TatD_DNase PF01026.21 KFR03798.1 - 2e-47 161.7 0.0 2.4e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase TRC8_N PF13705.6 KFR03799.1 - 4.1e-173 576.9 41.9 4.7e-173 576.6 41.9 1.0 1 0 0 1 1 1 1 TRC8 N-terminal domain zf-RING_2 PF13639.6 KFR03799.1 - 4.8e-09 36.4 8.6 4.8e-09 36.4 8.6 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFR03799.1 - 7.6e-09 35.3 7.6 7.6e-09 35.3 7.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFR03799.1 - 1.1e-07 32.0 8.3 4.5e-07 30.1 8.3 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFR03799.1 - 1.7e-06 27.8 8.0 1.7e-06 27.8 8.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFR03799.1 - 7.3e-05 22.6 8.0 7.3e-05 22.6 8.0 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFR03799.1 - 8.5e-05 22.3 5.4 8.5e-05 22.3 5.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFR03799.1 - 8.7e-05 22.5 5.8 0.0011 18.9 5.8 2.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KFR03799.1 - 8.7e-05 22.3 4.9 0.00022 21.0 4.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KFR03799.1 - 0.0005 19.7 6.1 0.0005 19.7 6.1 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KFR03799.1 - 0.0021 18.0 7.9 0.006 16.6 7.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.8 KFR03799.1 - 0.078 13.2 8.5 2.2 8.5 8.5 3.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_10 PF16685.5 KFR03799.1 - 0.24 11.6 3.7 0.57 10.4 3.7 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-P11 PF03854.14 KFR03799.1 - 0.55 9.9 5.4 2.3 7.9 5.4 2.1 1 0 0 1 1 1 0 P-11 zinc finger Zf_RING PF16744.5 KFR03799.1 - 0.93 9.6 7.2 0.35 11.0 4.2 1.8 2 0 0 2 2 1 0 KIAA1045 RING finger FYDLN_acid PF09538.10 KFR03799.1 - 2.7 8.7 6.1 5 7.9 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Zn_ribbon_17 PF17120.5 KFR03799.1 - 6.5 6.5 13.1 0.73 9.5 8.0 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type TMEM65 PF10507.9 KFR03801.1 - 4.2e-47 158.6 2.7 4.9e-47 158.4 2.7 1.0 1 0 0 1 1 1 1 Transmembrane protein 65 Romo1 PF10247.9 KFR03801.1 - 0.059 13.7 2.0 0.23 11.9 0.0 2.2 2 1 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 DUF2273 PF10031.9 KFR03801.1 - 9.7 6.3 10.0 0.17 11.9 1.2 2.5 3 0 0 3 3 3 0 Small integral membrane protein (DUF2273) C2 PF00168.30 KFR03803.1 - 2.4e-72 239.8 0.1 8.7e-16 58.1 0.0 7.5 6 1 0 6 6 6 6 C2 domain Ferlin_C PF16165.5 KFR03803.1 - 7.8e-41 139.6 4.0 1.2e-38 132.5 0.1 4.4 4 2 2 6 6 6 2 Ferlin C-terminus FerB PF08150.12 KFR03803.1 - 3.8e-31 107.5 0.6 9.3e-31 106.3 0.1 2.1 2 0 0 2 2 2 1 FerB (NUC096) domain FerI PF08151.12 KFR03803.1 - 1.3e-19 70.0 0.0 3.9e-19 68.5 0.0 1.9 1 0 0 1 1 1 1 FerI (NUC094) domain Synaptobrevin PF00957.21 KFR03803.1 - 1.6 8.5 7.1 4 7.3 7.1 1.6 1 0 0 1 1 1 0 Synaptobrevin Annexin PF00191.20 KFR03804.1 - 5.6e-99 324.2 12.8 2.3e-25 88.4 0.9 4.0 4 0 0 4 4 4 4 Annexin Myb_DNA-bind_7 PF15963.5 KFR03804.1 - 0.00023 21.0 1.2 1.6 8.7 0.0 4.1 3 1 1 4 4 4 2 Myb DNA-binding like Acetyltransf_11 PF13720.6 KFR03804.1 - 0.0016 18.8 0.9 3.9 8.0 0.0 3.2 3 0 0 3 3 3 2 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF5343 PF17278.2 KFR03804.1 - 0.1 12.7 3.8 1.2 9.3 0.2 3.4 4 1 0 4 4 4 0 Family of unknown function (DUF5343) TSLP PF15216.6 KFR03804.1 - 0.28 11.5 1.5 20 5.5 0.0 3.4 3 1 1 4 4 4 0 Thymic stromal lymphopoietin Kelch_1 PF01344.25 KFR03805.1 - 3.6e-38 128.9 0.1 3.3e-10 39.4 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFR03805.1 - 1.6e-31 107.6 0.2 1.2e-05 25.4 0.0 6.7 3 2 4 7 7 7 6 Kelch motif BTB PF00651.31 KFR03805.1 - 1.1e-25 90.0 0.2 2.5e-25 88.9 0.2 1.6 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KFR03805.1 - 1.2e-24 86.4 0.4 1.2e-24 86.4 0.4 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 KFR03805.1 - 1.4e-23 82.6 0.0 0.0019 18.4 0.0 6.8 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KFR03805.1 - 1.2e-21 76.4 1.7 6.7e-06 26.0 0.0 6.7 4 2 2 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KFR03805.1 - 5.4e-21 73.7 1.6 6.3e-05 22.8 0.0 6.4 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.6 KFR03805.1 - 1.9e-12 46.8 1.3 0.18 11.9 0.1 6.4 6 0 0 6 6 6 4 Kelch motif DUF3342 PF11822.8 KFR03805.1 - 0.0073 16.5 0.7 0.16 12.2 0.1 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3342) Skp1_POZ PF03931.15 KFR03805.1 - 0.022 14.9 0.0 0.07 13.3 0.0 1.8 2 0 0 2 2 1 0 Skp1 family, tetramerisation domain YqgB PF11036.8 KFR03805.1 - 0.12 12.1 0.6 0.28 10.9 0.6 1.6 1 0 0 1 1 1 0 Virulence promoting factor Elongin_A PF06881.11 KFR03806.1 - 0.00028 21.4 0.1 0.00089 19.8 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box-like PF12937.7 KFR03806.1 - 0.0024 17.7 0.2 0.0086 16.0 0.2 2.0 1 0 0 1 1 1 1 F-box-like Pox_A8 PF04745.12 KFR03806.1 - 0.012 14.7 0.6 0.017 14.2 0.6 1.3 1 0 0 1 1 1 0 VITF-3 subunit protein F-box PF00646.33 KFR03806.1 - 0.033 14.1 0.5 0.17 11.8 0.1 2.5 2 0 0 2 2 2 0 F-box domain Nt_Gln_amidase PF09764.9 KFR03807.1 - 1.3e-63 214.0 0.0 1.4e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase AAA PF00004.29 KFR03808.1 - 1e-47 161.9 0.0 1.9e-41 141.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 KFR03808.1 - 9e-18 64.1 0.0 2.3e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Bromodomain AAA_lid_3 PF17862.1 KFR03808.1 - 2.9e-12 46.2 0.2 8.1e-12 44.8 0.2 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KFR03808.1 - 3.2e-06 27.7 0.4 0.0004 20.8 0.1 3.6 3 1 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 KFR03808.1 - 6.6e-06 26.0 0.0 0.00063 19.5 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 KFR03808.1 - 8.3e-05 22.8 0.0 0.0004 20.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFR03808.1 - 0.00039 20.7 2.3 0.05 13.9 0.2 4.4 3 2 1 4 4 4 1 AAA domain AAA_18 PF13238.6 KFR03808.1 - 0.00048 20.7 0.0 0.026 15.1 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.14 KFR03808.1 - 0.00097 19.1 0.1 0.1 12.6 0.1 3.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFR03808.1 - 0.0051 16.6 0.0 0.06 13.1 0.0 2.8 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KFR03808.1 - 0.0061 16.3 0.1 1.2 8.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Rer1 PF03248.13 KFR03808.1 - 0.024 14.3 0.1 0.048 13.4 0.1 1.4 1 0 0 1 1 1 0 Rer1 family AAA_33 PF13671.6 KFR03808.1 - 0.025 14.7 0.0 0.14 12.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KFR03808.1 - 0.026 14.0 0.5 31 3.9 0.1 4.1 5 0 0 5 5 5 0 Bacterial TniB protein RNA_helicase PF00910.22 KFR03808.1 - 0.035 14.5 0.0 0.088 13.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KFR03808.1 - 0.051 12.9 0.0 0.25 10.7 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KFR03808.1 - 0.094 11.9 0.0 0.26 10.5 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain Sigma54_activ_2 PF14532.6 KFR03808.1 - 0.11 12.7 0.0 1.5 9.0 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 KFR03808.1 - 0.11 12.7 0.1 0.53 10.5 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.6 KFR03808.1 - 0.15 11.9 4.4 0.71 9.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KFR03808.1 - 0.16 11.5 0.0 0.66 9.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region Dehydrin PF00257.19 KFR03808.1 - 5.8 7.5 5.7 0.97 10.0 0.3 2.0 2 0 0 2 2 2 0 Dehydrin Homeodomain PF00046.29 KFR03809.1 - 4.5e-29 100.1 8.2 1.2e-07 31.5 0.0 4.4 4 0 0 4 4 4 4 Homeodomain zf_C2H2_ZHX PF18387.1 KFR03809.1 - 2.9e-24 84.5 3.8 3.9e-24 84.0 0.6 2.4 2 0 0 2 2 2 1 Zinc-fingers and homeoboxes C2H2 finger domain Homez PF11569.8 KFR03809.1 - 1.5e-18 66.0 1.9 8.7e-12 44.3 0.3 4.3 4 0 0 4 4 4 3 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 KFR03809.1 - 1e-14 54.1 9.0 0.00085 19.2 0.2 4.9 5 0 0 5 5 5 4 Homeobox KN domain zf-C2H2 PF00096.26 KFR03809.1 - 5.9 7.5 7.1 15 6.3 0.6 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF5588 PF17826.1 KFR03810.1 - 3.9e-94 315.5 4.8 1.2e-93 313.9 4.8 1.7 1 1 0 1 1 1 1 Family of unknown function (DUF5588) TPR_12 PF13424.6 KFR03810.1 - 0.062 13.6 0.1 0.16 12.3 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat FAM83 PF07894.12 KFR03812.1 - 4.8e-100 334.6 0.1 6e-100 334.3 0.1 1.1 1 0 0 1 1 1 1 FAM83 A-H PLDc_2 PF13091.6 KFR03812.1 - 0.00049 20.0 0.0 0.00097 19.0 0.0 1.5 1 0 0 1 1 1 1 PLD-like domain RabGAP-TBC PF00566.18 KFR03813.1 - 1.2e-09 38.2 6.3 6.4e-09 35.8 6.3 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain WD40 PF00400.32 KFR03813.1 - 1.4e-07 32.1 5.6 2.8 9.0 0.6 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR03813.1 - 1.4e-05 25.3 0.4 1.8 8.9 0.0 4.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KFR03813.1 - 0.0079 16.7 0.0 3.6 8.2 0.0 2.6 2 0 0 2 2 2 2 PQQ-like domain Nbas_N PF15492.6 KFR03813.1 - 0.11 11.8 0.0 0.44 9.8 0.0 1.9 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal DER1 PF04511.15 KFR03814.1 - 1.7e-57 194.4 9.8 2e-57 194.2 9.8 1.0 1 0 0 1 1 1 1 Der1-like family DUF3341 PF11821.8 KFR03814.1 - 0.041 13.5 0.3 0.087 12.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) Chitin_synth_2 PF03142.15 KFR03817.1 - 1e-18 67.3 2.8 1e-14 54.1 0.7 3.4 2 1 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.6 KFR03817.1 - 4.1e-18 66.1 0.0 2.4e-16 60.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KFR03817.1 - 6.2e-09 35.9 0.0 0.00021 21.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 KFR03817.1 - 1.7e-06 28.1 17.8 1.8e-05 24.8 17.8 2.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KFR03817.1 - 0.0016 18.0 0.0 0.0038 16.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 Tweety PF04906.13 KFR03817.1 - 0.071 11.8 0.1 0.071 11.8 0.1 1.7 2 0 0 2 2 2 0 Tweety DUF3742 PF12553.8 KFR03817.1 - 0.33 11.1 2.0 0.87 9.7 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3742) PH_17 PF18012.1 KFR03819.1 - 4.1e-28 96.9 0.1 1.1e-27 95.5 0.1 1.8 1 0 0 1 1 1 1 PH domain PDZ PF00595.24 KFR03819.1 - 5.2e-19 68.4 0.5 1e-18 67.5 0.5 1.4 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 KFR03819.1 - 1.4e-14 54.4 0.0 1.7e-09 38.1 0.0 2.3 2 0 0 2 2 2 2 PH domain PDZ_6 PF17820.1 KFR03819.1 - 3.3e-05 23.6 0.1 9.3e-05 22.2 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFR03819.1 - 8.7e-05 22.8 0.0 0.00033 20.9 0.1 1.9 2 0 0 2 2 2 1 PDZ domain MTBP_mid PF14919.6 KFR03820.1 - 1.2e-150 501.5 0.7 1.9e-150 500.8 0.7 1.4 1 0 0 1 1 1 1 MDM2-binding MTBP_C PF14920.6 KFR03820.1 - 1.9e-125 417.8 8.5 3.5e-125 416.9 8.5 1.5 1 0 0 1 1 1 1 MDM2-binding MTBP_N PF14918.6 KFR03820.1 - 4.2e-98 327.9 1.3 7.4e-98 327.1 1.3 1.4 1 0 0 1 1 1 1 MDM2-binding AKAP2_C PF15304.6 KFR03820.1 - 0.0095 15.3 4.5 0.015 14.6 4.5 1.3 1 0 0 1 1 1 1 A-kinase anchor protein 2 C-terminus Ribosomal_L13 PF00572.18 KFR03821.1 - 2.8e-08 34.1 0.1 3.7e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 VWA PF00092.28 KFR03822.1 - 2.5e-111 369.8 0.0 1.4e-54 185.0 0.2 2.7 2 0 0 2 2 2 2 von Willebrand factor type A domain fn3 PF00041.21 KFR03822.1 - 4.6e-94 308.9 8.5 7.7e-14 51.8 0.0 8.3 8 0 0 8 8 8 8 Fibronectin type III domain Collagen PF01391.18 KFR03822.1 - 3.3e-37 126.0 166.5 2.4e-08 33.6 26.0 5.5 2 2 3 5 5 5 5 Collagen triple helix repeat (20 copies) VWA_2 PF13519.6 KFR03822.1 - 1.4e-31 109.3 0.0 6.1e-17 62.2 0.0 3.0 3 0 0 3 3 3 2 von Willebrand factor type A domain DUF2369 PF10179.9 KFR03822.1 - 2e-07 31.3 1.1 8.3 6.9 0.1 6.7 7 0 0 7 7 7 1 Uncharacterised conserved protein (DUF2369) Interfer-bind PF09294.10 KFR03822.1 - 1.7e-06 28.3 0.0 13 6.2 0.0 6.4 7 0 0 7 7 7 1 Interferon-alpha/beta receptor, fibronectin type III DUF4959 PF16323.5 KFR03822.1 - 0.00015 22.0 0.0 0.22 11.8 0.0 4.3 4 0 0 4 4 4 1 Domain of unknown function (DUF4959) CBM_4_9 PF02018.17 KFR03822.1 - 0.83 9.9 3.9 4.3 7.6 0.2 3.4 5 0 0 5 5 5 0 Carbohydrate binding domain DEP PF00610.21 KFR03823.1 - 3.5e-47 158.3 2.0 7.2e-26 90.1 0.3 2.3 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ_6 PF17820.1 KFR03823.1 - 2e-06 27.5 0.0 3.5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFR03823.1 - 0.01 16.1 0.0 0.025 14.9 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Complex1_LYR_2 PF13233.6 KFR03823.1 - 0.011 16.4 2.1 0.038 14.8 2.1 2.0 1 1 0 1 1 1 0 Complex1_LYR-like PDZ PF00595.24 KFR03823.1 - 0.085 13.2 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 PDZ domain MCM6_C PF18263.1 KFR03823.1 - 0.36 11.1 2.2 2.1 8.6 0.1 2.7 2 1 0 2 2 2 0 MCM6 C-terminal winged-helix domain Dcc1 PF09724.9 KFR03824.1 - 1.1e-89 301.1 2.3 1.2e-89 300.9 2.3 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Peptidase_M1_N PF17900.1 KFR03825.1 - 3.9e-06 27.2 0.1 8.1e-05 22.9 0.1 2.4 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 KFR03825.1 - 0.0035 16.9 1.7 0.0086 15.7 1.7 1.7 1 1 0 1 1 1 1 Peptidase family M1 domain HEAT_2 PF13646.6 KFR03825.1 - 0.018 15.4 0.1 0.84 10.1 0.0 3.3 3 1 0 3 3 3 0 HEAT repeats HEAT PF02985.22 KFR03825.1 - 0.45 10.9 3.2 9.6 6.8 0.0 4.2 5 0 0 5 5 5 0 HEAT repeat Phosphodiest PF01663.22 KFR03826.1 - 4.2e-77 260.1 0.0 8.7e-75 252.5 0.0 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.17 KFR03826.1 - 1.3e-15 57.5 45.0 1.1e-08 35.3 13.8 3.1 3 0 0 3 3 3 2 Somatomedin B domain Endonuclease_NS PF01223.23 KFR03826.1 - 2.1e-10 40.8 0.0 3.8e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Sulfatase PF00884.23 KFR03826.1 - 6.4e-05 22.5 0.0 0.019 14.4 0.0 2.2 2 0 0 2 2 2 2 Sulfatase Cys_knot PF00007.22 KFR03827.1 - 3.2e-15 56.3 14.9 3.2e-15 56.3 14.9 2.8 3 0 0 3 3 3 1 Cystine-knot domain VWC PF00093.18 KFR03827.1 - 5.9e-12 45.7 8.9 5.9e-12 45.7 8.9 4.3 2 1 0 2 2 2 1 von Willebrand factor type C domain TSP_1 PF00090.19 KFR03827.1 - 0.00011 22.3 9.1 0.00011 22.3 9.1 2.7 3 1 0 3 3 3 1 Thrombospondin type 1 domain MARVEL PF01284.23 KFR03828.1 - 3e-10 40.3 9.2 3.3e-10 40.2 9.2 1.0 1 0 0 1 1 1 1 Membrane-associating domain SieB PF14163.6 KFR03828.1 - 0.12 11.9 3.5 0.33 10.4 3.0 1.8 1 1 0 1 1 1 0 Super-infection exclusion protein B 2-oxoacid_dh PF00198.23 KFR03828.1 - 0.12 11.7 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) DUF3687 PF12459.8 KFR03828.1 - 0.56 9.8 7.1 0.11 12.0 2.1 2.1 1 1 1 2 2 2 0 D-Ala-teichoic acid biosynthesis protein DUF4131 PF13567.6 KFR03828.1 - 0.94 9.1 5.1 0.62 9.7 3.7 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF4227 PF14004.6 KFR03828.1 - 3.5 7.7 6.4 0.43 10.6 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4227) Lectin_C PF00059.21 KFR03829.1 - 1.6e-18 67.4 0.0 2.4e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain Collagen PF01391.18 KFR03829.1 - 9.5e-11 41.3 52.1 1.3e-06 28.1 20.2 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) TNFR_c6 PF00020.18 KFR03830.1 - 6.6e-29 100.0 34.8 2.1e-10 40.8 11.0 4.6 4 0 0 4 4 4 4 TNFR/NGFR cysteine-rich region Death PF00531.22 KFR03830.1 - 4.1e-16 58.9 0.7 5.2e-09 36.2 0.0 2.4 2 0 0 2 2 2 2 Death domain BCDHK_Adom3 PF10436.9 KFR03830.1 - 0.0085 15.9 3.6 0.045 13.6 3.6 1.9 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase tRNA_NucTran2_2 PF13735.6 KFR03830.1 - 0.43 10.5 3.7 1.5 8.8 0.8 2.4 1 1 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative SAM_2 PF07647.17 KFR03831.1 - 1.2e-17 63.8 0.9 1.6e-17 63.3 0.9 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFR03831.1 - 1.5e-11 44.5 0.9 2.2e-11 44.0 0.9 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFR03831.1 - 8.8e-09 35.2 0.1 1.3e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PAPS_reduct PF01507.19 KFR03831.1 - 0.072 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Tcf25 PF04910.14 KFR03831.1 - 0.092 11.8 0.2 0.1 11.7 0.2 1.0 1 0 0 1 1 1 0 Transcriptional repressor TCF25 RVT_1 PF00078.27 KFR03832.1 - 0.0011 18.6 0.0 0.0021 17.6 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_transf_64 PF09258.10 KFR03833.1 - 1.5e-106 355.2 0.8 1.9e-106 354.8 0.8 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 KFR03833.1 - 4.7e-25 88.4 0.1 1.1e-24 87.3 0.0 1.6 2 0 0 2 2 2 1 Exostosin family Med30 PF11315.8 KFR03834.1 - 1.5e-65 219.9 1.6 1.7e-65 219.7 1.6 1.0 1 0 0 1 1 1 1 Mediator complex subunit 30 MetOD2 PF18548.1 KFR03834.1 - 0.061 13.4 1.5 0.14 12.2 1.5 1.6 1 0 0 1 1 1 0 Metanogen output domain 2 UPF0449 PF15136.6 KFR03834.1 - 0.092 13.2 3.9 0.21 12.0 3.9 1.9 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 NYD-SP28_assoc PF14775.6 KFR03834.1 - 0.27 11.4 4.7 0.56 10.3 4.7 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain Cation_efflux PF01545.21 KFR03836.1 - 5.3e-40 137.3 16.7 7.7e-40 136.8 16.7 1.3 1 0 0 1 1 1 1 Cation efflux family SMP_2 PF10144.9 KFR03836.1 - 0.97 9.1 4.0 0.43 10.2 0.1 2.4 3 0 0 3 3 3 0 Bacterial virulence factor haemolysin DUF1230 PF06799.11 KFR03836.1 - 1.2 9.2 3.5 2.9 8.0 0.2 2.6 3 0 0 3 3 3 0 Conserved in the green lineage and diatoms 27 Rad21_Rec8_N PF04825.13 KFR03837.1 - 1.6e-40 137.6 0.0 3.4e-40 136.6 0.0 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KFR03837.1 - 7.6e-23 79.6 0.2 3.6e-22 77.4 0.1 2.2 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 KFR03837.1 - 0.0013 18.7 0.1 0.0013 18.7 0.1 1.8 2 0 0 2 2 2 1 Segregation and condensation protein ScpA SUIM_assoc PF16619.5 KFR03837.1 - 6.6 6.9 13.5 0.041 14.0 3.5 2.6 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Fcf1 PF04900.12 KFR03839.1 - 2e-24 85.8 0.6 4.5e-24 84.7 0.0 1.8 2 0 0 2 2 2 1 Fcf1 Presenilin PF01080.17 KFR03839.1 - 8.3 5.1 5.2 9.4 4.9 5.2 1.1 1 0 0 1 1 1 0 Presenilin JAB PF01398.21 KFR03840.1 - 3.1e-20 72.3 0.3 3.1e-20 72.3 0.3 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease zf-H2C2_5 PF13909.6 KFR03841.1 - 0.0049 16.6 2.3 0.0049 16.6 2.3 8.2 8 1 0 8 8 8 5 C2H2-type zinc-finger domain zf_C2H2_ZHX PF18387.1 KFR03841.1 - 0.022 14.4 39.0 0.19 11.4 1.0 6.7 6 2 1 7 7 7 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF2024 PF09630.10 KFR03841.1 - 0.59 10.0 0.0 0.59 10.0 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF2024) DUF5472 PF17566.2 KFR03841.1 - 0.8 9.7 4.1 27 4.8 0.1 4.2 4 1 1 5 5 5 0 Family of unknown function (DUF5472) Actin_micro PF17003.5 KFR03841.1 - 5.7 6.0 28.1 3.4 6.8 0.2 5.4 5 1 0 5 5 5 0 Putative actin-like family OrgA_MxiK PF09482.10 KFR03842.1 - 0.061 13.2 0.0 0.061 13.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial type III secretion apparatus protein (OrgA_MxiK) DUF4462 PF14692.6 KFR03842.1 - 0.08 12.4 0.5 0.13 11.7 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) RVT_1 PF00078.27 KFR03848.1 - 1.2e-33 116.6 0.0 1.6e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 KFR03848.1 - 9.6e-08 31.8 0.1 1.5e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase thumb domain PMP22_Claudin PF00822.20 KFR03850.1 - 3.1e-10 40.2 0.0 3.5e-10 40.0 0.0 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFR03850.1 - 3.1e-06 27.1 0.1 3.6e-06 26.9 0.1 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction WD40 PF00400.32 KFR03862.1 - 2e-41 139.2 22.8 1.1e-05 26.0 0.2 10.8 10 1 0 10 10 10 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR03862.1 - 2.6e-21 75.7 0.2 8.7e-06 26.0 0.0 7.0 3 3 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFR03862.1 - 6.1e-12 45.8 0.2 0.006 16.5 0.0 5.2 2 1 2 5 5 5 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFR03862.1 - 8.8e-05 21.6 4.7 0.033 13.1 0.0 4.9 3 2 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KFR03862.1 - 0.00014 21.6 0.7 7.5 6.6 0.0 4.9 4 1 1 5 5 5 2 WD40-like Beta Propeller Repeat IKI3 PF04762.12 KFR03862.1 - 0.0024 16.0 0.0 0.22 9.5 0.0 2.9 2 1 0 3 3 3 1 IKI3 family BBS2_Mid PF14783.6 KFR03862.1 - 0.0048 16.9 0.0 0.15 12.2 0.0 3.2 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.21 KFR03862.1 - 0.0056 16.6 0.4 0.024 14.5 0.1 2.4 2 0 0 2 2 2 1 PQQ enzyme repeat Sugar_tr PF00083.24 KFR03863.1 - 1.1e-110 370.6 25.6 1.3e-110 370.4 25.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFR03863.1 - 7.2e-31 107.4 45.4 1e-23 83.9 23.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily 7tm_1 PF00001.21 KFR03864.1 - 1.9e-74 250.3 14.6 2.4e-74 250.0 14.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR03864.1 - 3.6e-13 49.5 10.6 8.4e-08 31.9 3.7 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFR03864.1 - 1.9e-06 27.7 19.0 3.3e-06 26.9 12.3 2.8 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFR03864.1 - 0.014 15.2 4.8 0.027 14.2 4.4 1.9 1 1 0 1 1 1 0 Olfactory receptor zf-LITAF-like PF10601.9 KFR03864.1 - 6.9 7.0 11.3 0.41 11.0 3.0 2.9 2 1 1 3 3 3 0 LITAF-like zinc ribbon domain Otopetrin PF03189.13 KFR03865.1 - 6.9e-50 170.2 21.6 4.3e-20 72.0 1.3 3.7 2 1 0 3 3 3 3 Otopetrin DUF1345 PF07077.11 KFR03865.1 - 0.0084 15.8 6.0 0.96 9.1 1.4 3.2 2 1 1 3 3 3 3 Protein of unknown function (DUF1345) VirB8 PF04335.13 KFR03866.1 - 0.33 10.8 0.0 0.33 10.8 0.0 1.6 2 0 0 2 2 2 0 VirB8 protein zf-H2C2_2 PF13465.6 KFR03867.1 - 6.7e-45 149.6 51.6 7.3e-09 35.7 3.8 8.4 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFR03867.1 - 8.4e-36 120.5 53.1 5.4e-06 26.6 1.1 8.2 8 0 0 8 8 7 7 Zinc finger, C2H2 type BTB PF00651.31 KFR03867.1 - 2e-25 89.1 0.8 4.3e-25 88.1 0.8 1.6 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.6 KFR03867.1 - 7.1e-25 85.6 46.0 0.00086 20.0 0.9 8.3 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFR03867.1 - 6.5e-15 55.0 30.6 0.0077 16.5 0.7 8.6 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFR03867.1 - 5.8e-14 51.7 50.8 6.9e-05 22.7 0.3 7.7 7 0 0 7 7 7 5 C2H2-type zinc finger zf-met PF12874.7 KFR03867.1 - 4.2e-09 36.5 46.9 0.014 15.8 0.5 9.0 10 0 0 10 10 10 5 Zinc-finger of C2H2 type zf_UBZ PF18439.1 KFR03867.1 - 1.1e-07 31.3 23.4 1 9.0 0.1 7.6 7 0 0 7 7 7 3 Ubiquitin-Binding Zinc Finger GAGA PF09237.11 KFR03867.1 - 1e-05 25.2 12.5 0.17 11.7 0.1 5.2 2 2 3 5 5 5 3 GAGA factor zf-C2H2_11 PF16622.5 KFR03867.1 - 0.0055 16.4 40.3 0.0082 15.9 1.5 7.4 8 0 0 8 8 7 3 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KFR03867.1 - 0.013 15.6 27.8 0.71 10.0 1.4 5.4 2 2 5 7 7 7 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 KFR03867.1 - 0.099 12.6 29.6 0.47 10.4 0.5 7.0 7 0 0 7 7 7 0 zinc-finger of a C2HC-type zf-MYST PF17772.1 KFR03867.1 - 0.81 9.3 18.1 32 4.2 0.1 6.0 5 2 1 6 6 6 0 MYST family zinc finger domain ARS2 PF04959.13 KFR03867.1 - 0.86 10.0 9.6 9.4 6.6 0.1 4.0 1 1 0 3 3 3 0 Arsenite-resistance protein 2 zf-RING_7 PF02591.15 KFR03867.1 - 0.9 9.8 0.0 0.9 9.8 0.0 5.1 7 0 0 7 7 5 0 C4-type zinc ribbon domain DUF3268 PF11672.8 KFR03867.1 - 1.4 9.3 16.9 3.3 8.1 0.4 4.5 2 2 1 4 4 4 0 zinc-finger-containing domain BolA PF01722.18 KFR03867.1 - 5.6 7.3 9.2 13 6.2 0.3 4.5 2 1 1 4 4 3 0 BolA-like protein FYVE PF01363.21 KFR03867.1 - 5.8 7.1 37.0 7.7 6.7 1.1 5.7 1 1 3 4 4 4 0 FYVE zinc finger ADK_lid PF05191.14 KFR03867.1 - 7.7 6.6 19.2 20 5.2 0.1 5.4 3 1 0 3 3 3 0 Adenylate kinase, active site lid Calcyon PF06387.11 KFR03868.1 - 5.5e-88 293.7 0.1 6.3e-88 293.5 0.1 1.0 1 0 0 1 1 1 1 D1 dopamine receptor-interacting protein (calcyon) MgsA_C PF12002.8 KFR03868.1 - 0.05 13.5 0.3 0.088 12.7 0.3 1.4 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal DUF2448 PF10476.9 KFR03868.1 - 0.13 12.1 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) zf-LITAF-like PF10601.9 KFR03868.1 - 0.3 11.4 1.4 0.35 11.2 0.2 1.6 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Syntaxin-18_N PF10496.9 KFR03869.1 - 1.4e-09 38.0 0.4 1.4e-09 38.0 0.4 2.2 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus Phage_Integr_2 PF13009.6 KFR03869.1 - 0.00046 19.4 0.6 0.0007 18.8 0.6 1.3 1 0 0 1 1 1 1 Putative phage integrase Homeodomain PF00046.29 KFR03870.1 - 1e-21 76.5 4.7 1.4e-21 76.0 4.7 1.2 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 KFR03870.1 - 0.19 11.2 0.6 0.86 9.1 0.1 2.0 1 1 1 2 2 2 0 Homeodomain leucine-zipper encoding, Homez CYTL1 PF15153.6 KFR03871.1 - 3.5e-57 191.8 3.4 4.1e-57 191.6 3.4 1.0 1 0 0 1 1 1 1 Cytokine-like protein 1 DUF1599 PF07659.11 KFR03871.1 - 0.022 15.2 0.0 0.13 12.7 0.0 2.0 2 0 0 2 2 2 0 Nucleotide modification associated domain 1 Pkinase PF00069.25 KFR03872.1 - 3.2e-58 197.2 0.0 3.6e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR03872.1 - 2.7e-32 112.1 0.1 3.6e-32 111.7 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR03872.1 - 1.3e-10 41.1 0.0 1.4e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFR03872.1 - 0.00014 21.0 0.1 0.00017 20.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KFR03872.1 - 0.00056 18.8 0.0 0.00082 18.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFR03872.1 - 0.0016 18.4 0.4 0.0021 18.0 0.4 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFR03872.1 - 0.18 11.1 1.7 0.15 11.4 0.4 1.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family BAG6 PF12057.8 KFR03874.1 - 0.073 12.7 5.1 5.4 6.7 1.3 2.9 2 0 0 2 2 2 0 BCL2-associated athanogene 6 KNOX2 PF03791.13 KFR03874.1 - 0.44 10.1 6.4 8.1 6.0 0.7 4.0 3 0 0 3 3 3 0 KNOX2 domain Tfb5 PF06331.12 KFR03874.1 - 1.8 8.6 7.4 0.22 11.6 0.9 2.8 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 DUF948 PF06103.11 KFR03874.1 - 6.6 7.1 6.7 4.4 7.6 0.3 3.5 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Amidohydro_1 PF01979.20 KFR03875.1 - 8.9e-34 117.3 0.0 1.1e-33 117.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFR03875.1 - 3.8e-10 39.8 0.0 3.7e-07 30.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.14 KFR03875.1 - 0.026 14.3 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 Amidohydrolase JAKMIP_CC3 PF16034.5 KFR03877.1 - 5.3e-86 287.7 21.8 5.3e-86 287.7 21.8 6.7 5 2 1 6 6 6 1 JAKMIP CC3 domain ADIP PF11559.8 KFR03877.1 - 0.012 15.7 13.6 0.012 15.7 13.6 8.5 5 4 5 10 10 10 0 Afadin- and alpha -actinin-Binding DUF1654 PF07867.11 KFR03877.1 - 0.024 14.4 0.1 0.13 12.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) WD40 PF00400.32 KFR03880.1 - 2.1e-07 31.5 4.7 1.6 9.7 0.1 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR03880.1 - 0.0013 18.9 0.0 17 5.8 0.0 4.5 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Glyco_hydro_38N PF01074.22 KFR03881.1 - 6.7e-81 271.8 4.6 1.1e-80 271.1 4.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KFR03881.1 - 6.1e-27 95.1 1.1 1.1e-26 94.2 1.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KFR03881.1 - 4.5e-18 65.2 0.0 1e-17 64.0 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KFR03881.1 - 1.8e-08 34.4 0.0 4.5e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain S_100 PF01023.19 KFR03882.1 - 3.5e-20 71.4 0.1 8.9e-20 70.1 0.1 1.8 2 0 0 2 2 2 1 S-100/ICaBP type calcium binding domain EF-hand_6 PF13405.6 KFR03882.1 - 9.8e-08 31.3 0.5 0.00018 21.2 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KFR03882.1 - 1.3e-07 32.0 0.3 1.7e-07 31.6 0.3 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFR03882.1 - 6e-06 25.4 3.1 3e-05 23.2 0.5 2.8 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 KFR03882.1 - 0.0006 19.6 0.2 0.00088 19.1 0.2 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_4 PF12763.7 KFR03882.1 - 0.011 15.7 0.1 0.013 15.5 0.1 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 KFR03882.1 - 0.021 14.3 2.6 0.31 10.6 1.4 2.7 2 0 0 2 2 2 0 EF hand DEK_C PF08766.11 KFR03882.1 - 0.042 13.8 0.1 0.079 12.9 0.1 1.4 1 0 0 1 1 1 0 DEK C terminal domain RabGAP-TBC PF00566.18 KFR03883.1 - 4.7e-50 170.2 0.0 1.1e-49 169.0 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ARGLU PF15346.6 KFR03883.1 - 7.1 6.5 15.0 1.8 8.4 7.4 2.2 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 SWIRM PF04433.17 KFR03884.1 - 0.04 14.3 0.6 0.12 12.7 0.0 2.1 2 1 0 2 2 2 0 SWIRM domain Pertussis_S1 PF02917.14 KFR03884.1 - 0.057 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 GrpE PF01025.19 KFR03885.1 - 3.5e-45 153.6 4.7 4.2e-45 153.4 4.7 1.1 1 0 0 1 1 1 1 GrpE Cpn60_TCP1 PF00118.24 KFR03885.1 - 0.015 14.0 2.3 0.017 13.7 2.3 1.1 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family Laminin_I PF06008.14 KFR03885.1 - 0.016 14.9 8.7 0.02 14.6 8.7 1.1 1 0 0 1 1 1 0 Laminin Domain I MetJ PF01340.20 KFR03885.1 - 0.033 14.2 0.7 0.12 12.3 0.1 2.0 1 1 1 2 2 2 0 Met Apo-repressor, MetJ LOH1CR12 PF10158.9 KFR03885.1 - 0.038 14.0 1.3 0.052 13.6 1.3 1.3 1 0 0 1 1 1 0 Tumour suppressor protein DUF3391 PF11871.8 KFR03885.1 - 0.13 12.8 5.6 0.27 11.8 5.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF2205 PF10224.9 KFR03885.1 - 0.28 11.2 6.8 0.16 12.0 4.1 1.9 1 1 1 2 2 2 0 Short coiled-coil protein CRR7 PF12095.8 KFR03885.1 - 0.4 11.2 5.7 0.17 12.4 2.6 1.9 2 1 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 DUF1993 PF09351.10 KFR03885.1 - 0.43 10.7 2.6 10 6.2 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) DUF3347 PF11827.8 KFR03885.1 - 0.85 9.8 6.5 1.1 9.4 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Sortilin-Vps10 PF15902.5 KFR03886.1 - 8.6e-95 318.1 0.8 1.3e-94 317.5 0.8 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KFR03886.1 - 1.2e-36 126.6 2.6 1.9e-36 126.0 2.6 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal PKD PF00801.20 KFR03886.1 - 3.5e-08 33.2 0.0 1.7e-06 27.8 0.0 2.9 3 0 0 3 3 3 1 PKD domain BNR PF02012.20 KFR03886.1 - 0.0068 16.2 10.0 2.4 8.5 0.3 5.1 5 0 0 5 5 5 2 BNR/Asp-box repeat PH PF00169.29 KFR03887.1 - 2.9e-26 92.0 1.4 1.3e-12 48.1 0.9 2.7 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KFR03887.1 - 1.5e-05 25.4 2.7 0.026 14.9 0.0 4.0 3 1 0 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.6 KFR03887.1 - 0.0001 22.6 1.3 1.6 9.1 0.6 4.2 2 2 0 2 2 2 2 Pleckstrin homology domain Sharpin_PH PF16764.5 KFR03887.1 - 0.0034 17.1 0.2 0.012 15.3 0.0 2.0 2 0 0 2 2 2 1 Sharpin PH domain ERM PF00769.19 KFR03887.1 - 0.0042 16.9 7.7 0.0042 16.9 7.7 2.0 2 1 0 2 2 2 1 Ezrin/radixin/moesin family Spc7 PF08317.11 KFR03887.1 - 0.12 11.2 15.5 0.27 10.1 15.5 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Nup188_C PF18378.1 KFR03887.1 - 0.91 8.3 3.9 1.5 7.6 3.9 1.3 1 0 0 1 1 1 0 Nuclear pore protein NUP188 C-terminal domain Prefoldin_2 PF01920.20 KFR03887.1 - 1.2 9.1 18.5 0.51 10.3 4.7 3.1 3 0 0 3 3 3 0 Prefoldin subunit AbLIM_anchor PF16182.5 KFR03888.1 - 1e-117 394.2 31.9 1.2e-76 259.0 23.9 2.3 1 1 1 2 2 2 2 Putative adherens-junction anchoring region of AbLIM LIM PF00412.22 KFR03888.1 - 1.6e-40 137.1 42.2 2e-13 50.3 2.6 4.3 4 0 0 4 4 4 4 LIM domain VHP PF02209.19 KFR03888.1 - 5.9e-16 58.2 2.5 1.2e-15 57.3 2.5 1.6 1 0 0 1 1 1 1 Villin headpiece domain TPR_12 PF13424.6 KFR03889.1 - 9.5e-17 61.1 40.5 2e-06 28.0 4.0 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 KFR03889.1 - 7.1e-09 35.2 51.8 0.22 11.8 0.7 12.6 13 1 1 14 14 13 6 Tetratricopeptide repeat TPR_2 PF07719.17 KFR03889.1 - 3.8e-05 23.5 47.8 0.32 11.2 0.4 11.8 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFR03889.1 - 0.00013 21.7 23.6 0.039 14.0 0.2 8.4 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFR03889.1 - 0.00045 19.9 37.4 0.031 14.1 0.6 10.0 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFR03889.1 - 0.00072 20.0 7.7 0.041 14.4 0.5 4.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFR03889.1 - 0.0012 18.7 21.2 0.097 12.6 0.8 7.8 9 0 0 9 9 9 2 Tetratricopeptide repeat SH3_1 PF00018.28 KFR03889.1 - 0.0029 17.2 0.6 0.016 14.8 0.0 2.3 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFR03889.1 - 0.02 14.6 0.0 0.057 13.1 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain Csd3_N PF18059.1 KFR03889.1 - 0.098 13.2 0.1 0.41 11.2 0.1 2.1 1 0 0 1 1 1 0 Csd3 N-terminal TPR_14 PF13428.6 KFR03889.1 - 5.1 8.2 20.7 22 6.2 0.0 7.8 7 2 2 9 9 8 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFR03889.1 - 5.7 7.7 22.7 0.2 12.4 0.3 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat Trypsin_2 PF13365.6 KFR03890.1 - 3.2e-29 102.8 0.1 5.1e-29 102.1 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KFR03890.1 - 4.8e-15 56.0 0.0 7.2e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Trypsin IGFBP PF00219.18 KFR03890.1 - 4.4e-09 36.8 22.0 4.4e-09 36.8 22.0 2.1 2 0 0 2 2 2 1 Insulin-like growth factor binding protein Kazal_2 PF07648.15 KFR03890.1 - 2e-06 27.8 1.6 2e-06 27.8 1.6 1.9 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFR03890.1 - 3.3e-05 23.8 1.3 3.3e-05 23.8 1.3 2.8 2 1 0 2 2 2 1 Kazal-type serine protease inhibitor domain Peptidase_S46 PF10459.9 KFR03890.1 - 5.1e-05 22.1 1.7 0.051 12.2 0.2 2.1 2 0 0 2 2 2 2 Peptidase S46 Peptidase_S32 PF05579.13 KFR03890.1 - 0.001 18.3 0.1 0.52 9.5 0.0 2.1 2 0 0 2 2 2 2 Equine arteritis virus serine endopeptidase S32 DUF31 PF01732.16 KFR03890.1 - 0.043 13.4 0.4 5.8 6.3 0.1 2.1 2 0 0 2 2 2 0 Putative peptidase (DUF31) ACOX PF01756.19 KFR03891.1 - 3.3e-51 173.4 0.0 6.7e-51 172.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 KFR03891.1 - 1.3e-15 57.4 0.0 2.1e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KFR03891.1 - 4.1e-08 33.6 0.1 8.3e-07 29.3 0.1 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 KFR03891.1 - 8.5e-07 29.6 0.0 2e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal AdoMet_MTase PF07757.13 KFR03892.1 - 6.3e-41 139.2 0.1 1.2e-40 138.3 0.1 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MetW PF07021.12 KFR03892.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KFR03892.1 - 0.043 13.8 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KFR03892.1 - 0.058 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KFR03892.1 - 0.072 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain 7tm_1 PF00001.21 KFR03894.1 - 6.5e-36 124.0 19.4 7.9e-36 123.7 19.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 KFR03894.1 - 0.37 10.5 13.9 0.38 10.5 12.3 1.8 1 1 1 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 Peptidase_M14 PF00246.24 KFR03895.1 - 4.1e-75 253.3 0.0 5.3e-75 252.9 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Fz PF01392.22 KFR03895.1 - 2.9e-21 76.1 2.6 6.4e-21 75.1 2.6 1.6 1 0 0 1 1 1 1 Fz domain CarboxypepD_reg PF13620.6 KFR03895.1 - 2.6e-15 56.4 0.0 5.1e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KFR03895.1 - 1.4e-06 28.2 0.0 2.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 CarboxypepD_reg-like domain Glypican PF01153.19 KFR03895.1 - 0.0098 14.8 1.5 0.015 14.2 1.5 1.1 1 0 0 1 1 1 1 Glypican AstE_AspA PF04952.14 KFR03895.1 - 0.02 14.0 0.0 1.6 7.7 0.1 2.8 3 1 0 3 3 3 0 Succinylglutamate desuccinylase / Aspartoacylase family 7tm_1 PF00001.21 KFR03896.1 - 9.4e-76 254.6 4.6 1.2e-75 254.2 4.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR03896.1 - 8.5e-11 41.7 14.5 4.7e-08 32.7 4.0 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFR03896.1 - 5.2e-07 29.7 10.2 2.6e-06 27.4 3.1 2.4 3 0 0 3 3 3 2 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFR03896.1 - 1e-05 25.3 9.8 1e-05 25.3 9.8 2.8 2 2 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx FA_desaturase PF00487.24 KFR03896.1 - 0.016 15.0 0.0 0.016 15.0 0.0 2.7 2 2 1 3 3 3 0 Fatty acid desaturase DUF4614 PF15391.6 KFR03896.1 - 0.23 11.4 8.4 0.43 10.6 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Alpha-2-MRAP_C PF06401.11 KFR03897.1 - 2.3e-72 243.4 29.1 2.3e-72 243.4 29.1 1.6 2 0 0 2 2 2 1 Alpha-2-macroglobulin RAP, C-terminal domain Alpha-2-MRAP_N PF06400.11 KFR03897.1 - 1.1e-26 93.1 29.2 1.7e-23 82.9 3.6 3.5 2 1 0 3 3 3 3 Alpha-2-macroglobulin RAP, N-terminal domain Cellulase-like PF12876.7 KFR03897.1 - 0.021 14.2 0.1 0.042 13.2 0.1 1.4 1 0 0 1 1 1 0 Sugar-binding cellulase-like Med30 PF11315.8 KFR03897.1 - 0.68 10.1 14.8 0.061 13.5 6.5 2.7 1 1 2 3 3 3 0 Mediator complex subunit 30 DUF5053 PF16476.5 KFR03897.1 - 1.6 8.5 4.8 5.2 6.8 0.1 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF5053) IRS PF02174.17 KFR03898.1 - 1.1e-08 34.9 0.0 2.6e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 PTB domain (IRS-1 type) Trypsin PF00089.26 KFR03899.1 - 3.2e-74 249.5 0.4 4.5e-74 249.0 0.4 1.2 1 0 0 1 1 1 1 Trypsin Kringle PF00051.18 KFR03899.1 - 4.8e-26 90.9 1.8 4.8e-26 90.9 1.8 2.5 3 0 0 3 3 3 1 Kringle domain fn2 PF00040.19 KFR03899.1 - 5.1e-15 55.5 17.2 1.7e-14 53.8 7.6 3.1 2 0 0 2 2 2 2 Fibronectin type II domain fn1 PF00039.18 KFR03899.1 - 1.6e-09 37.8 1.5 1.6e-09 37.8 1.5 3.6 3 0 0 3 3 3 1 Fibronectin type I domain EGF PF00008.27 KFR03899.1 - 2.4e-07 30.9 28.6 3.9e-06 27.0 7.7 3.9 4 0 0 4 4 4 2 EGF-like domain DUF1986 PF09342.11 KFR03899.1 - 5.2e-06 26.8 0.1 1.4e-05 25.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) hEGF PF12661.7 KFR03899.1 - 0.04 14.6 4.3 0.04 14.6 4.3 4.4 3 0 0 3 3 3 0 Human growth factor-like EGF EGF_2 PF07974.13 KFR03899.1 - 0.041 14.3 31.8 0.037 14.4 8.6 4.1 3 0 0 3 3 3 0 EGF-like domain RGS12_us1 PF16613.5 KFR03902.1 - 3.3e-57 191.9 15.1 3.3e-57 191.9 15.1 3.5 5 0 0 5 5 3 1 Unstructured region of RGS12 RGS12_usC PF16612.5 KFR03902.1 - 3.8e-57 192.6 2.4 3.8e-57 192.6 2.4 3.3 3 1 0 3 3 3 1 C-terminal unstructured region of RGS12 RBD PF02196.15 KFR03902.1 - 4.3e-32 110.0 0.0 2.9e-20 72.1 0.0 2.7 2 0 0 2 2 2 2 Raf-like Ras-binding domain RGS PF00615.19 KFR03902.1 - 2.6e-28 98.7 3.6 4.9e-28 97.8 3.6 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS12_us2 PF16611.5 KFR03902.1 - 3e-28 98.0 9.8 3e-28 98.0 9.8 3.2 4 0 0 4 4 2 1 Unstructured region between RBD and GoLoco PDZ PF00595.24 KFR03902.1 - 9.1e-14 51.6 0.1 1.4e-12 47.8 0.0 3.0 2 1 1 3 3 3 1 PDZ domain GoLoco PF02188.17 KFR03902.1 - 4.3e-09 35.7 0.3 1.1e-08 34.5 0.3 1.7 1 0 0 1 1 1 1 GoLoco motif PDZ_6 PF17820.1 KFR03902.1 - 2.5e-08 33.7 0.0 6.1e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PID PF00640.23 KFR03902.1 - 0.00018 21.5 0.0 0.00051 20.1 0.0 1.7 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDZ_2 PF13180.6 KFR03902.1 - 0.00081 19.7 0.0 0.0034 17.7 0.0 2.1 1 0 0 1 1 1 1 PDZ domain TUG-UBL1 PF11470.8 KFR03902.1 - 0.0011 19.1 0.3 0.23 11.7 0.0 4.0 5 0 0 5 5 5 1 TUG ubiquitin-like domain PT-HINT PF07591.11 KFR03902.1 - 0.017 15.3 0.0 0.048 13.9 0.0 1.7 1 0 0 1 1 1 0 Pretoxin HINT domain Myb_DNA-bind_4 PF13837.6 KFR03904.1 - 4.2e-12 46.3 1.5 4.2e-12 46.3 1.5 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KFR03904.1 - 0.0045 17.3 0.2 0.0045 17.3 0.2 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF87 PF01935.17 KFR03904.1 - 0.63 10.1 4.4 1.3 9.1 2.4 2.0 1 1 1 2 2 2 0 Helicase HerA, central domain MCM_OB PF17207.3 KFR03904.1 - 0.86 9.5 4.4 4.4 7.2 0.1 2.4 2 1 0 2 2 2 0 MCM OB domain Myb_DNA-bind_3 PF12776.7 KFR03904.1 - 2.7 9.0 7.6 1.9 9.6 0.6 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF3652 PF12372.8 KFR03905.1 - 1.2e-21 76.3 1.8 5.7e-21 74.1 0.7 2.9 2 0 0 2 2 2 1 Huntingtin protein region HEAT PF02985.22 KFR03905.1 - 3.4e-09 36.2 10.5 0.038 14.3 0.1 8.1 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.6 KFR03905.1 - 2.5e-05 24.7 3.2 2.2 8.9 0.0 6.1 4 1 2 6 6 6 3 HEAT-like repeat HEAT_2 PF13646.6 KFR03905.1 - 6.6e-05 23.2 0.3 2.4 8.6 0.0 5.2 3 2 2 5 5 5 2 HEAT repeats Vac14_Fab1_bd PF12755.7 KFR03905.1 - 0.0026 18.3 0.6 2 9.1 0.0 3.8 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region PRANC PF09372.10 KFR03905.1 - 0.16 12.3 0.5 4 7.8 0.2 3.1 3 0 0 3 3 3 0 PRANC domain Pkinase PF00069.25 KFR03906.1 - 8.4e-64 215.5 0.0 1.1e-63 215.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR03906.1 - 5.6e-34 117.6 0.0 7.7e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 KFR03906.1 - 4.8e-22 78.4 0.1 1.1e-21 77.2 0.1 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain Kinase-like PF14531.6 KFR03906.1 - 3.4e-05 23.3 0.0 5.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFR03906.1 - 0.00026 19.9 0.0 0.0006 18.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Nop14 PF04147.12 KFR03907.1 - 1e-263 877.7 40.0 1.1e-263 877.5 40.0 1.0 1 0 0 1 1 1 1 Nop14-like family DUF2810 PF10928.8 KFR03907.1 - 0.00032 20.7 0.4 0.051 13.6 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2810) PAP_central PF04928.17 KFR03907.1 - 3.8 6.4 6.5 5.2 6.0 4.7 2.1 2 0 0 2 2 2 0 Poly(A) polymerase central domain MFS_1 PF07690.16 KFR03908.1 - 3.6e-39 134.7 45.9 1.9e-33 115.9 25.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFR03908.1 - 1.8e-11 43.6 9.1 1.8e-11 43.6 9.1 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KFR03908.1 - 7.5e-07 27.9 3.1 7.5e-07 27.9 3.1 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KFR03908.1 - 0.018 13.9 0.4 0.018 13.9 0.4 3.3 1 1 2 3 3 3 0 MFS_1 like family Abhydro_lipase PF04083.16 KFR03908.1 - 0.045 13.3 0.0 0.12 11.9 0.0 1.7 1 1 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Deltameth_res PF16020.5 KFR03908.1 - 0.11 12.4 0.0 0.73 9.7 0.0 2.5 1 0 0 1 1 1 0 Deltamethrin resistance Aldolase_II PF00596.21 KFR03909.1 - 1.5e-44 152.2 0.1 2.3e-44 151.6 0.1 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PH PF00169.29 KFR03910.1 - 1.5e-19 70.4 0.2 3.1e-19 69.4 0.2 1.6 1 0 0 1 1 1 1 PH domain SH2 PF00017.24 KFR03910.1 - 5.5e-05 23.2 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 SH2 domain PH_6 PF15406.6 KFR03910.1 - 0.007 16.7 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain EABR PF12180.8 KFR03912.1 - 7e-16 57.5 4.5 7e-16 57.5 4.5 2.2 2 0 0 2 2 2 1 TSG101 and ALIX binding domain of CEP55 CC2-LZ PF16516.5 KFR03912.1 - 1.8e-08 34.7 12.3 1.8e-08 34.7 12.3 4.3 2 2 2 4 4 4 2 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator FlxA PF14282.6 KFR03912.1 - 0.0067 16.4 5.8 0.0067 16.4 5.8 4.9 1 1 4 5 5 5 1 FlxA-like protein PRKG1_interact PF15898.5 KFR03912.1 - 0.065 14.1 0.6 0.065 14.1 0.6 4.9 2 1 2 4 4 4 0 cGMP-dependent protein kinase interacting domain DUF1192 PF06698.11 KFR03912.1 - 0.26 11.3 0.1 0.26 11.3 0.1 4.6 4 2 0 4 4 4 0 Protein of unknown function (DUF1192) FAM193_C PF15914.5 KFR03913.1 - 5.3e-31 106.1 0.9 1.4e-30 104.8 0.9 1.8 1 0 0 1 1 1 1 FAM193 family C-terminal Sec34 PF04136.15 KFR03913.1 - 0.0027 17.6 1.5 0.0027 17.6 1.5 3.0 3 0 0 3 3 3 1 Sec34-like family Desmo_N PF06771.11 KFR03913.1 - 0.056 13.8 0.9 0.43 10.9 0.4 2.4 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus zf-RING_UBOX PF13445.6 KFR03914.1 - 4.5e-11 42.6 0.7 4.5e-11 42.6 0.7 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFR03914.1 - 7.3e-11 42.2 5.9 1.9e-10 40.9 5.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFR03914.1 - 1.9e-10 40.4 6.9 6.7e-10 38.6 6.9 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFR03914.1 - 1e-09 38.1 5.4 1.9e-09 37.2 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFR03914.1 - 1.7e-09 37.5 5.9 3.2e-09 36.6 5.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFR03914.1 - 1.2e-08 34.7 6.8 2.4e-08 33.7 6.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFR03914.1 - 3.1e-06 27.0 5.7 3.1e-06 27.0 5.7 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KFR03914.1 - 5.1e-06 26.2 3.8 1.3e-05 24.9 3.9 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KFR03914.1 - 0.0005 20.3 8.2 0.0023 18.2 8.2 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KFR03914.1 - 0.00065 19.8 8.5 0.013 15.7 8.6 2.5 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KFR03914.1 - 0.018 14.7 2.9 0.064 13.0 2.9 2.0 1 0 0 1 1 1 0 RING-like zinc finger zf-UDP PF14569.6 KFR03914.1 - 0.022 14.9 5.2 0.022 14.9 5.2 2.0 1 1 1 2 2 2 0 Zinc-binding RING-finger Rtf2 PF04641.12 KFR03914.1 - 0.023 14.1 5.8 0.027 13.8 4.0 1.9 1 1 1 2 2 2 0 Rtf2 RING-finger zf-RING_6 PF14835.6 KFR03914.1 - 0.038 13.9 5.5 0.15 12.0 5.5 1.9 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-P11 PF03854.14 KFR03914.1 - 0.054 13.2 1.9 0.054 13.2 1.9 2.1 2 0 0 2 2 2 0 P-11 zinc finger Zn_ribbon_17 PF17120.5 KFR03914.1 - 0.17 11.5 7.7 0.22 11.1 6.8 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_10 PF16685.5 KFR03914.1 - 0.24 11.5 8.9 0.53 10.5 8.9 1.7 1 1 0 1 1 1 0 zinc RING finger of MSL2 DZR PF12773.7 KFR03914.1 - 0.32 11.1 8.7 0.087 12.9 4.2 2.1 1 1 1 2 2 2 0 Double zinc ribbon DUF1272 PF06906.11 KFR03914.1 - 0.35 11.0 6.0 0.9 9.7 6.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) zf-Nse PF11789.8 KFR03914.1 - 0.68 9.8 5.5 6.8 6.6 5.8 2.2 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Prim_Zn_Ribbon PF08273.12 KFR03914.1 - 1.8 8.9 5.3 0.95 9.8 1.3 2.3 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase Zn-ribbon_8 PF09723.10 KFR03914.1 - 2.7 8.2 8.0 31 4.8 5.8 2.6 2 0 0 2 2 2 0 Zinc ribbon domain FYVE PF01363.21 KFR03914.1 - 3.4 7.9 11.1 26 5.0 11.1 2.2 1 1 0 1 1 1 0 FYVE zinc finger zinc_ribbon_2 PF13240.6 KFR03914.1 - 7.5 6.4 9.4 21 5.0 4.8 3.2 2 1 1 3 3 3 0 zinc-ribbon domain zf-RING_2 PF13639.6 KFR03915.1 - 2.3e-10 40.6 5.9 2.3e-10 40.6 5.9 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFR03915.1 - 2.4e-10 40.1 7.0 8.9e-10 38.3 7.0 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFR03915.1 - 1.1e-09 38.0 5.4 2.4e-09 36.9 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFR03915.1 - 1.8e-09 37.4 5.9 4e-09 36.3 5.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFR03915.1 - 8.3e-09 35.3 9.2 2.3e-08 33.9 9.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFR03915.1 - 1.1e-08 34.8 6.5 2.8e-08 33.5 6.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFR03915.1 - 2.7e-06 27.1 12.8 3.7e-06 26.7 5.7 2.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KFR03915.1 - 3.3e-06 26.8 3.1 9.5e-06 25.3 3.1 1.8 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KFR03915.1 - 0.00048 20.4 7.9 0.0029 17.9 8.0 2.1 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KFR03915.1 - 0.0014 18.7 9.4 0.029 14.5 9.4 2.5 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 KFR03915.1 - 0.003 17.7 6.2 0.013 15.5 4.4 2.2 2 0 0 2 2 2 1 Zinc-binding RING-finger Rtf2 PF04641.12 KFR03915.1 - 0.0096 15.3 4.5 0.023 14.1 4.5 1.8 1 1 0 1 1 1 1 Rtf2 RING-finger zf-RING_6 PF14835.6 KFR03915.1 - 0.063 13.2 5.7 0.24 11.3 5.7 2.0 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-P11 PF03854.14 KFR03915.1 - 0.11 12.1 5.3 0.064 12.9 1.9 2.2 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_11 PF17123.5 KFR03915.1 - 0.13 12.1 5.7 0.077 12.8 2.9 2.2 2 0 0 2 2 2 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 KFR03915.1 - 0.13 11.9 7.5 0.068 12.8 4.9 1.9 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_10 PF16685.5 KFR03915.1 - 0.27 11.4 8.8 0.59 10.3 8.8 1.7 1 1 0 1 1 1 0 zinc RING finger of MSL2 DZR PF12773.7 KFR03915.1 - 0.57 10.3 9.0 0.093 12.8 4.0 2.1 1 1 1 2 2 2 0 Double zinc ribbon DUF1272 PF06906.11 KFR03915.1 - 0.57 10.3 6.2 1.2 9.3 6.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) IBR PF01485.21 KFR03915.1 - 0.72 10.1 7.2 0.27 11.5 3.2 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-Nse PF11789.8 KFR03915.1 - 0.86 9.5 5.2 4.3 7.2 5.2 2.2 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prim_Zn_Ribbon PF08273.12 KFR03915.1 - 1.9 8.8 5.0 0.98 9.7 1.1 2.2 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase HypA PF01155.19 KFR03915.1 - 2.7 8.1 6.0 7 6.7 6.0 1.8 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FYVE PF01363.21 KFR03915.1 - 3.1 8.0 10.8 23 5.2 10.8 2.3 1 1 0 1 1 1 0 FYVE zinc finger Glyco_hydro_115 PF15979.5 KFR03916.1 - 0.058 12.8 4.9 0.14 11.6 4.9 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 115 UMPH-1 PF05822.12 KFR03916.1 - 8.1 5.9 8.4 11 5.5 7.2 1.8 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) HLH PF00010.26 KFR03918.1 - 6.1e-12 45.3 3.0 4.4e-11 42.6 3.4 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Myc-LZ PF02344.15 KFR03918.1 - 0.0023 18.0 8.0 0.0023 18.0 8.0 2.5 2 0 0 2 2 2 1 Myc leucine zipper domain Striatin PF08232.12 KFR03918.1 - 0.02 15.5 6.2 0.18 12.4 1.0 2.1 2 0 0 2 2 2 0 Striatin family UPF0449 PF15136.6 KFR03918.1 - 1.1 9.8 6.8 0.51 10.8 2.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Tugs PF17840.1 KFR03918.1 - 2.1 8.6 9.7 0.12 12.6 3.5 2.0 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain HAUS-augmin3 PF14932.6 KFR03919.1 - 3.7e-82 275.8 26.3 3.7e-82 275.8 26.3 4.1 4 0 0 4 4 4 2 HAUS augmin-like complex subunit 3 Baculo_PEP_C PF04513.12 KFR03919.1 - 0.021 14.9 1.6 0.021 14.9 1.6 4.7 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus HsbA PF12296.8 KFR03919.1 - 1.1 9.7 9.1 0.67 10.4 0.1 3.8 4 0 0 4 4 4 0 Hydrophobic surface binding protein A DNA_pol_A PF00476.20 KFR03920.1 - 2.5e-121 405.3 4.1 3.1e-121 405.0 4.1 1.1 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_P_Exo PF18049.1 KFR03920.1 - 2.1e-87 292.0 4.6 1.1e-86 289.6 3.9 2.5 2 1 0 2 2 2 1 DNA polymerase nu pseudo-exo FOXP-CC PF16159.5 KFR03920.1 - 0.058 14.0 0.0 0.22 12.1 0.0 2.0 1 0 0 1 1 1 0 FOXP coiled-coil domain Acetyltransf_1 PF00583.25 KFR03922.1 - 1.9e-14 53.9 0.1 2.5e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFR03922.1 - 3.8e-13 49.7 0.1 5.4e-13 49.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFR03922.1 - 2.5e-12 46.8 0.1 4.4e-12 46.0 0.1 1.4 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFR03922.1 - 2.2e-07 30.9 0.1 7.2e-06 26.0 0.0 2.0 1 1 1 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 KFR03922.1 - 9.1e-05 22.0 0.1 0.00068 19.2 0.1 2.0 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_3 PF13302.7 KFR03922.1 - 0.00013 22.7 0.1 0.00017 22.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFR03922.1 - 0.00096 19.1 1.2 0.0024 17.8 0.1 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.6 KFR03922.1 - 0.0034 17.1 0.0 0.0044 16.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFR03922.1 - 0.0036 17.4 0.1 0.045 13.8 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFR03922.1 - 0.0081 16.3 0.0 0.011 15.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KFR03922.1 - 0.15 11.6 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Neuropep_like PF15161.6 KFR03923.1 - 8.8e-29 99.0 0.1 1.1e-28 98.7 0.1 1.1 1 0 0 1 1 1 1 Neuropeptide-like Neuropep_like PF15161.6 KFR03924.1 - 4.3e-42 141.6 1.8 5.8e-42 141.2 1.8 1.2 1 0 0 1 1 1 1 Neuropeptide-like LETM1 PF07766.13 KFR03925.1 - 1.5e-110 368.8 7.7 1.5e-110 368.8 7.7 3.7 2 1 1 4 4 4 2 LETM1-like protein EF-hand_6 PF13405.6 KFR03925.1 - 0.0035 17.2 0.6 1.1 9.4 0.2 3.7 2 1 1 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 KFR03925.1 - 0.011 15.3 0.3 0.22 11.1 0.1 2.9 2 0 0 2 2 2 0 EF hand SAP PF02037.27 KFR03925.1 - 0.015 15.0 0.2 0.015 15.0 0.2 3.3 3 0 0 3 3 3 0 SAP domain EF-hand_8 PF13833.6 KFR03925.1 - 0.036 13.9 1.2 0.81 9.6 0.1 3.2 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_7 PF13499.6 KFR03925.1 - 0.039 14.4 3.3 0.15 12.6 0.0 3.5 4 0 0 4 4 4 0 EF-hand domain pair MinC_N PF05209.13 KFR03925.1 - 0.091 12.7 2.1 0.77 9.7 0.0 3.3 4 0 0 4 4 4 0 Septum formation inhibitor MinC, N-terminal domain Acetyltransf_11 PF13720.6 KFR03925.1 - 0.19 12.2 2.2 0.77 10.3 0.2 3.2 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Pkinase_Tyr PF07714.17 KFR03926.1 - 3.9e-105 350.8 0.0 6e-105 350.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR03926.1 - 7e-45 153.4 0.0 9.9e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.16 KFR03926.1 - 8.1e-37 125.2 0.0 5.3e-14 52.1 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR03926.1 - 6.9e-36 122.7 0.2 1.7e-12 47.7 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFR03926.1 - 8e-27 93.4 0.1 5.5e-10 39.4 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFR03926.1 - 2.7e-24 85.1 0.2 6.5e-08 32.7 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain FGFR3_TM PF18123.1 KFR03926.1 - 6.5e-15 54.4 7.1 1.1e-14 53.6 7.1 1.4 1 0 0 1 1 1 1 Fibroblast growth factor receptor 3 transmembrane domain V-set PF07686.17 KFR03926.1 - 1.6e-14 54.0 8.6 2.6e-05 24.3 0.1 5.4 4 3 1 5 5 5 3 Immunoglobulin V-set domain Ig_5 PF16681.5 KFR03926.1 - 1.3e-08 35.1 0.0 0.61 10.5 0.0 4.1 3 1 0 3 3 3 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFR03926.1 - 3.3e-08 33.7 0.0 0.0006 20.0 0.0 3.9 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFR03926.1 - 4.1e-06 26.3 0.0 0.67 9.6 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 KFR03926.1 - 0.00056 19.9 0.1 0.05 13.7 0.0 3.1 3 1 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFR03926.1 - 0.0061 16.6 0.0 18 5.4 0.0 3.5 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain V-set_CD47 PF08204.11 KFR03926.1 - 0.033 14.2 1.0 0.96 9.4 0.0 3.1 3 1 0 3 3 3 0 CD47 immunoglobulin-like domain Shisa PF13908.6 KFR03926.1 - 0.072 13.3 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Orthoreo_P10 PF07204.11 KFR03926.1 - 0.08 12.9 0.1 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 Pkinase_fungal PF17667.1 KFR03926.1 - 0.18 10.5 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase TACC_C PF05010.14 KFR03928.1 - 1.5e-89 299.1 39.2 1.5e-89 299.1 39.2 1.7 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal AAA_13 PF13166.6 KFR03928.1 - 0.69 8.5 24.9 1.8 7.1 24.9 1.6 1 0 0 1 1 1 0 AAA domain DUF948 PF06103.11 KFR03928.1 - 0.94 9.8 8.1 3.2 8.1 0.5 3.7 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Occludin_ELL PF07303.13 KFR03928.1 - 4.5 8.1 23.6 0.36 11.6 9.8 3.6 1 1 2 3 3 3 0 Occludin homology domain ZapD PF07072.11 KFR03928.1 - 9 6.0 13.9 0.35 10.6 1.8 3.1 1 1 2 3 3 3 0 Cell division protein Fib_alpha PF08702.10 KFR03928.1 - 9.6 6.4 25.2 14 5.8 11.9 3.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Tmpp129 PF10272.9 KFR03929.1 - 2.6e-66 224.4 0.0 2.8e-66 224.2 0.0 1.0 1 0 0 1 1 1 1 Putative transmembrane protein precursor DUF3577 PF12101.8 KFR03929.1 - 0.051 13.4 0.0 0.075 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3577) SLBP_RNA_bind PF15247.6 KFR03930.1 - 4.9e-30 103.5 4.2 1.1e-29 102.4 4.2 1.6 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain SLBP_RNA_bind PF15247.6 KFR03931.1 - 5.1e-29 100.2 3.3 1.4e-28 98.8 3.3 1.8 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain Carla_C4 PF01623.17 KFR03931.1 - 0.12 12.3 0.2 0.23 11.4 0.2 1.5 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein APG12 PF04110.13 KFR03933.1 - 6.5e-05 23.3 0.1 8.3e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF5549 PF17703.1 KFR03933.1 - 0.017 14.7 1.5 0.019 14.6 1.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5549) Peptidase_C65 PF10275.9 KFR03936.1 - 9.4e-83 277.4 0.2 1.3e-82 277.0 0.2 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 KFR03936.1 - 7.3e-06 26.5 0.0 0.00062 20.3 0.0 2.4 1 1 0 1 1 1 1 OTU-like cysteine protease CAP_GLY PF01302.25 KFR03940.1 - 4e-74 244.6 4.7 2.4e-24 85.1 0.5 3.3 3 0 0 3 3 3 3 CAP-Gly domain Ank_2 PF12796.7 KFR03940.1 - 2e-11 44.3 0.7 8.1e-07 29.5 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFR03940.1 - 1.8e-06 28.4 0.2 0.00019 21.9 0.1 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 KFR03940.1 - 3e-05 24.3 4.6 0.015 15.7 0.2 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KFR03940.1 - 0.00041 20.6 2.1 1.1 10.0 0.1 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KFR03940.1 - 0.0093 16.3 2.3 1.5 9.2 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Tubulin-binding PF00418.19 KFR03940.1 - 0.021 14.8 0.3 0.069 13.2 0.3 1.9 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat TrkA_C PF02080.21 KFR03940.1 - 0.085 12.7 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 0 TrkA-C domain CLASP_N PF12348.8 KFR03941.1 - 3.9e-15 56.0 6.5 7.4e-15 55.1 1.3 2.3 2 0 0 2 2 2 1 CLASP N terminal RTP1_C1 PF10363.9 KFR03941.1 - 2e-07 31.1 2.4 0.013 15.7 1.2 3.8 2 2 0 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 KFR03941.1 - 0.00032 21.1 2.8 4.9 7.8 0.0 5.4 6 0 0 6 6 6 1 HEAT-like repeat HEAT_2 PF13646.6 KFR03941.1 - 0.00053 20.3 6.4 1.2 9.6 0.0 4.4 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 KFR03941.1 - 0.023 14.9 8.9 11 6.5 0.0 6.4 7 0 0 7 7 7 0 HEAT repeat NUC173 PF08161.12 KFR03941.1 - 0.051 13.2 2.5 7.7 6.1 0.3 2.9 2 1 0 2 2 2 0 NUC173 domain DNA_alkylation PF08713.11 KFR03941.1 - 0.055 13.2 0.2 2.8 7.6 0.0 2.6 2 1 0 2 2 2 0 DNA alkylation repair enzyme Vac14_Fab1_bd PF12755.7 KFR03941.1 - 0.059 14.0 1.4 21 5.8 0.1 3.9 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region Dopey_N PF04118.14 KFR03941.1 - 0.087 11.9 1.5 1.5 7.8 0.1 2.4 2 1 0 2 2 2 0 Dopey, N-terminal DUF5578 PF17741.1 KFR03941.1 - 0.11 11.9 2.0 0.33 10.3 2.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5578) FAM199X PF15814.5 KFR03942.1 - 0.032 13.3 0.3 0.041 12.9 0.3 1.2 1 0 0 1 1 1 0 Protein family FAM199X Utp12 PF04003.12 KFR03944.1 - 4.7e-24 84.8 1.6 8.5e-24 83.9 1.6 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 KFR03944.1 - 7.7e-11 42.4 13.4 0.00013 22.7 0.9 4.5 3 1 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR03944.1 - 1.6e-09 37.9 0.1 0.0045 17.2 0.0 3.9 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFR03944.1 - 0.0014 18.0 0.0 0.0031 16.9 0.0 1.5 1 0 0 1 1 1 1 WD40-like domain UTP15_C PF09384.10 KFR03944.1 - 0.02 14.6 0.2 0.04 13.6 0.2 1.5 1 0 0 1 1 1 0 UTP15 C terminal GCD14 PF08704.10 KFR03945.1 - 1.8e-19 70.4 0.0 2.3e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KFR03945.1 - 3e-07 30.4 0.0 4e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KFR03945.1 - 5.9e-06 26.2 0.0 1.5e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFR03945.1 - 5.8e-05 23.7 0.0 0.00012 22.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KFR03945.1 - 0.00046 21.2 0.0 0.00071 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFR03945.1 - 0.013 16.1 0.0 0.024 15.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 KFR03945.1 - 0.23 11.0 0.0 0.31 10.5 0.0 1.1 1 0 0 1 1 1 0 Histone methylation protein DOT1 Spy1 PF11357.8 KFR03946.1 - 2e-59 199.5 5.8 2.9e-59 199.1 5.8 1.2 1 0 0 1 1 1 1 Cell cycle regulatory protein Thyroglobulin_1 PF00086.18 KFR03947.1 - 1e-10 41.1 3.3 1e-10 41.1 3.3 2.4 1 1 1 2 2 2 1 Thyroglobulin type-1 repeat Stevor PF17410.2 KFR03947.1 - 0.00025 20.7 0.0 0.00048 19.8 0.0 1.5 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame DUF4381 PF14316.6 KFR03947.1 - 0.016 15.5 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DAG1 PF05454.11 KFR03947.1 - 0.087 12.2 1.0 0.15 11.4 1.0 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) EphA2_TM PF14575.6 KFR03947.1 - 0.12 13.3 1.0 0.31 11.9 1.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RIFIN PF02009.16 KFR03947.1 - 2.9 7.7 5.6 4.2 7.2 5.5 1.4 1 1 0 1 1 1 0 Rifin MutS_V PF00488.21 KFR03948.1 - 5.1e-86 287.5 0.6 9.9e-86 286.6 0.6 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFR03948.1 - 3.2e-37 128.6 1.6 3.2e-37 128.6 1.6 2.5 3 0 0 3 3 3 1 MutS domain III MutS_II PF05188.17 KFR03948.1 - 1.7e-22 80.1 0.3 4.8e-22 78.7 0.0 1.9 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KFR03948.1 - 2.2e-20 72.8 2.3 6.1e-20 71.4 2.3 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 KFR03948.1 - 4.2e-05 23.8 0.0 0.00017 21.8 0.0 2.1 2 0 0 2 2 2 1 MutS domain I AAA_27 PF13514.6 KFR03948.1 - 0.0014 18.3 0.0 0.0046 16.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF2935 PF11155.8 KFR03948.1 - 0.023 15.0 0.9 6.2 7.2 0.3 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF2935) DUF3800 PF12686.7 KFR03948.1 - 0.37 11.4 1.8 1.8 9.2 1.7 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Ion_trans_2 PF07885.16 KFR03949.1 - 1.9e-20 72.6 19.2 1.5e-15 56.9 8.5 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 KFR03949.1 - 0.29 10.3 15.5 0.12 11.6 6.1 2.2 2 0 0 2 2 2 0 Ion transport protein Beta_helix PF13229.6 KFR03950.1 - 1.9e-78 261.8 69.5 1.1e-27 96.8 11.2 4.8 1 1 3 4 4 4 4 Right handed beta helix region NosD PF05048.13 KFR03950.1 - 3.9e-41 140.9 30.0 1.5e-17 63.7 8.8 3.9 1 1 3 4 4 4 4 Periplasmic copper-binding protein (NosD) F-box-like PF12937.7 KFR03950.1 - 6.7e-16 57.9 0.3 1.3e-15 57.0 0.3 1.5 1 0 0 1 1 1 1 F-box-like zf-UBR PF02207.20 KFR03950.1 - 4.6e-09 36.3 13.1 4.6e-09 36.3 13.1 2.1 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) F-box PF00646.33 KFR03950.1 - 5.1e-08 32.6 0.3 5.1e-08 32.6 0.3 1.8 2 0 0 2 2 2 1 F-box domain TFIIA PF03153.13 KFR03951.1 - 4.6e-117 392.5 11.8 7.7e-117 391.8 11.8 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Adap_comp_sub PF00928.21 KFR03951.1 - 7.6e-59 199.2 0.8 1.3e-58 198.5 0.8 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family SUIM_assoc PF16619.5 KFR03951.1 - 0.04 14.0 0.8 0.21 11.6 0.1 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 7tm_1 PF00001.21 KFR03952.1 - 1.8e-36 125.9 21.1 2.5e-36 125.4 21.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.6 KFR03952.1 - 5.9e-15 54.8 7.1 0.0002 21.1 0.2 4.8 1 1 5 6 6 6 6 Leucine rich repeat LRR_5 PF13306.6 KFR03952.1 - 6.4e-12 45.5 0.1 6.4e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) GnHR_trans PF12369.8 KFR03952.1 - 0.064 14.1 0.3 0.13 13.1 0.3 1.6 1 0 0 1 1 1 0 Gonadotropin hormone receptor transmembrane region LRR_4 PF12799.7 KFR03952.1 - 0.085 13.3 0.5 0.085 13.3 0.5 3.4 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFR03952.1 - 0.11 12.0 0.2 0.28 10.7 0.2 1.7 1 0 0 1 1 1 0 Leucine-rich repeat 7tm_1 PF00001.21 KFR03953.1 - 3.2e-35 121.7 27.9 4.6e-35 121.2 27.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GnHR_trans PF12369.8 KFR03953.1 - 7.3e-21 74.7 0.2 2e-20 73.4 0.2 1.7 1 0 0 1 1 1 1 Gonadotropin hormone receptor transmembrane region LRR_8 PF13855.6 KFR03953.1 - 2.5e-08 33.6 5.9 4.9e-05 23.0 0.8 3.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_5 PF13306.6 KFR03953.1 - 0.00017 21.5 0.5 0.00044 20.2 0.5 1.6 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFR03953.1 - 0.032 14.7 5.3 0.28 11.7 2.0 2.7 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) ANF_receptor PF01094.28 KFR03958.1 - 3.5e-15 56.0 0.1 4.1e-15 55.7 0.1 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 KFR03958.1 - 0.013 15.2 0.0 0.014 15.1 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein HATPase_c_3 PF13589.6 KFR03978.1 - 1.3e-13 51.0 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KFR03978.1 - 0.0014 19.1 0.0 0.0023 18.4 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ndc80_HEC PF03801.13 KFR03979.1 - 2.9e-49 166.6 0.0 1.4e-48 164.4 0.0 2.2 1 0 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 KFR03979.1 - 5.9e-32 109.6 2.8 5.9e-32 109.6 2.8 5.8 4 2 1 5 5 5 1 Domain of unknown function (DUF5595) DUF4164 PF13747.6 KFR03979.1 - 0.011 16.0 4.4 0.011 16.0 4.4 4.6 2 2 2 4 4 4 0 Domain of unknown function (DUF4164) bZIP_1 PF00170.21 KFR03979.1 - 0.025 14.7 0.8 0.025 14.7 0.8 5.7 4 2 3 7 7 7 0 bZIP transcription factor DUF1593 PF07632.11 KFR03979.1 - 0.032 13.7 0.3 0.073 12.5 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) HrpB7 PF09486.10 KFR03979.1 - 0.15 12.4 31.8 0.071 13.5 6.4 4.1 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB7) DUF3584 PF12128.8 KFR03979.1 - 2.1 5.7 40.0 0.57 7.6 17.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 KFR03979.1 - 3.3 7.7 20.3 1.2 9.1 4.7 3.9 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus MT-A70 PF05063.14 KFR03980.1 - 1.2e-40 139.2 0.9 1.7e-40 138.7 0.9 1.3 1 0 0 1 1 1 1 MT-A70 Pkinase_Tyr PF07714.17 KFR03981.1 - 6.4e-93 310.8 0.0 8.2e-93 310.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR03981.1 - 1.1e-45 156.1 0.0 1.4e-45 155.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFR03981.1 - 3.2e-28 97.7 0.2 6.2e-28 96.7 0.2 1.5 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFR03981.1 - 7.3e-20 70.3 0.4 3.3e-19 68.2 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFR03981.1 - 6.3e-15 54.8 0.0 1.9e-14 53.2 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFR03981.1 - 4.6e-11 42.2 0.1 1.4e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Haspin_kinase PF12330.8 KFR03981.1 - 0.0021 17.1 0.0 0.0038 16.2 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain SH3_10 PF17902.1 KFR03981.1 - 0.0042 17.1 0.0 0.0089 16.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.11 KFR03981.1 - 0.014 15.6 0.1 0.033 14.5 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain zf-RING_14 PF17978.1 KFR03981.1 - 0.057 13.9 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain YdjC PF04794.12 KFR03981.1 - 0.061 13.3 0.0 0.093 12.7 0.0 1.2 1 0 0 1 1 1 0 YdjC-like protein hSH3 PF14603.6 KFR03981.1 - 0.12 12.9 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Helically-extended SH3 domain Thymidylat_synt PF00303.19 KFR03982.1 - 4.5e-104 347.3 0.0 5e-104 347.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Clusterin PF01093.17 KFR03983.1 - 1.5e-171 571.2 3.9 1.8e-171 571.0 3.9 1.0 1 0 0 1 1 1 1 Clusterin Carbpep_Y_N PF05388.11 KFR03983.1 - 0.0028 18.2 3.3 0.44 11.1 2.9 3.1 3 1 1 4 4 4 1 Carboxypeptidase Y pro-peptide Sulfatase_C PF14707.6 KFR03983.1 - 0.064 14.0 8.9 1.2 9.9 0.0 3.4 2 1 0 3 3 3 0 C-terminal region of aryl-sulfatase P2 PF07194.11 KFR03983.1 - 0.15 12.1 3.3 16 5.6 0.0 3.7 3 1 0 3 3 3 0 P2 response regulator binding domain ALIX_LYPXL_bnd PF13949.6 KFR03983.1 - 0.27 10.5 10.3 1.6 7.9 6.2 3.3 3 1 1 4 4 4 0 ALIX V-shaped domain binding to HIV Collagen PF01391.18 KFR03984.1 - 6e-24 83.6 99.7 1.4e-09 37.5 32.7 3.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Lectin_C PF00059.21 KFR03984.1 - 3e-20 72.9 1.1 3e-20 72.9 1.1 2.3 2 0 0 2 2 2 1 Lectin C-type domain Filament PF00038.21 KFR03984.1 - 0.00044 19.9 29.2 0.00044 19.9 29.2 2.1 1 1 1 2 2 2 1 Intermediate filament protein Spc7 PF08317.11 KFR03984.1 - 0.0014 17.6 33.0 0.019 13.9 14.6 2.8 1 1 2 3 3 3 3 Spc7 kinetochore protein Fib_alpha PF08702.10 KFR03984.1 - 0.0071 16.5 37.8 0.015 15.5 7.6 3.9 1 1 3 4 4 4 2 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KFR03984.1 - 0.34 11.0 30.2 0.88 9.6 6.9 4.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 KFR03984.1 - 0.43 10.7 29.5 1.3 9.1 7.6 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Jnk-SapK_ap_N PF09744.9 KFR03984.1 - 0.65 10.2 26.7 0.29 11.4 4.8 3.3 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 HMMR_N PF15905.5 KFR03984.1 - 0.96 8.9 30.5 3 7.2 12.6 2.3 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal HalX PF08663.10 KFR03984.1 - 1.3 9.4 7.1 3.9 7.9 0.0 3.4 3 1 1 4 4 4 0 HalX domain DUF3584 PF12128.8 KFR03984.1 - 2.9 5.3 34.7 14 3.0 29.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) NPV_P10 PF05531.12 KFR03984.1 - 5 7.7 27.3 0.56 10.7 5.0 5.4 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 KFR03984.1 - 5.4 7.3 29.6 1.4 9.2 2.1 5.1 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) KapB PF08810.10 KFR03984.1 - 6.2 7.0 7.4 4.2 7.6 2.6 2.7 2 2 0 2 2 2 0 Kinase associated protein B Golgin_A5 PF09787.9 KFR03984.1 - 9.8 5.5 34.4 0.26 10.7 11.6 3.1 1 1 2 3 3 3 0 Golgin subfamily A member 5 efThoc1 PF11957.8 KFR03985.1 - 6e-147 490.2 8.9 9.4e-147 489.6 8.9 1.3 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Death PF00531.22 KFR03985.1 - 9.8e-18 64.1 1.5 4.5e-17 62.0 0.5 2.5 2 0 0 2 2 2 1 Death domain CTD_bind PF04818.13 KFR03985.1 - 0.83 10.5 3.0 34 5.4 0.0 4.2 4 0 0 4 4 4 0 RNA polymerase II-binding domain. JmjN PF02375.17 KFR03985.1 - 5.1 7.2 4.8 3.1 7.8 0.1 2.7 2 0 0 2 2 2 0 jmjN domain UCH PF00443.29 KFR03986.1 - 5.8e-50 170.2 0.6 6.8e-50 170.0 0.6 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFR03986.1 - 9.9e-13 48.4 4.1 2.6e-12 47.0 4.1 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KFR03986.1 - 0.00052 19.6 2.0 0.019 14.4 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase ubiquitin PF00240.23 KFR03986.1 - 0.0006 19.5 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family PFEMP PF03011.15 KFR03986.1 - 1.3 9.6 7.6 2 9.1 0.1 2.8 3 0 0 3 3 3 0 PFEMP DBL domain Pkinase PF00069.25 KFR03987.1 - 1.3e-62 211.6 0.0 1.3e-62 211.6 0.0 3.7 4 2 0 5 5 5 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR03987.1 - 7.8e-31 107.3 0.2 3.7e-30 105.1 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Rho_Binding PF08912.11 KFR03987.1 - 2.9e-23 82.4 14.2 2.9e-23 82.4 14.2 13.3 4 3 10 15 15 15 1 Rho Binding PH PF00169.29 KFR03987.1 - 5.1e-06 26.9 4.3 8.4e-05 23.0 0.1 3.4 3 0 0 3 3 3 1 PH domain C1_1 PF00130.22 KFR03987.1 - 0.0004 20.2 5.9 0.00083 19.2 5.9 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) APH PF01636.23 KFR03987.1 - 0.0012 18.9 0.3 0.029 14.3 0.2 2.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_C PF00433.24 KFR03987.1 - 0.0029 18.3 1.3 0.01 16.5 1.3 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain DUF1192 PF06698.11 KFR03987.1 - 0.005 16.9 0.7 0.005 16.9 0.7 4.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1192) HR1 PF02185.16 KFR03987.1 - 0.0068 16.5 13.5 0.0068 16.5 13.5 10.8 6 3 3 9 9 9 1 Hr1 repeat GREB1 PF15782.5 KFR03988.1 - 0 3175.6 18.5 0 1781.1 0.2 2.0 1 1 1 2 2 2 2 Gene regulated by oestrogen in breast cancer Rcd1 PF04078.13 KFR03988.1 - 0.0078 15.5 0.2 0.015 14.6 0.2 1.3 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like DoxA PF07680.11 KFR03988.1 - 0.13 12.1 0.0 0.49 10.3 0.0 1.9 2 0 0 2 2 2 0 TQO small subunit DoxA RecR PF02132.15 KFR03988.1 - 0.35 10.5 3.3 8.9 6.0 0.4 2.7 2 0 0 2 2 2 0 RecR protein Acetyltransf_13 PF13880.6 KFR03989.1 - 7.2e-30 102.8 0.0 1.5e-29 101.7 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 KFR03989.1 - 2.1e-15 56.3 0.0 5.3e-15 55.0 0.0 1.8 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Abhydrolase_1 PF00561.20 KFR03990.1 - 1.4e-09 38.0 0.0 3.1e-08 33.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFR03990.1 - 4.1e-09 36.1 0.0 6.7e-09 35.4 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFR03990.1 - 1.6e-06 28.9 0.0 2.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ank_2 PF12796.7 KFR03991.1 - 2.5e-48 162.6 10.5 7.3e-15 55.3 0.0 5.0 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFR03991.1 - 4.1e-47 157.6 13.3 2.8e-13 49.8 0.0 7.2 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFR03991.1 - 7.2e-46 154.0 19.7 3.5e-11 43.4 0.1 7.7 2 1 7 9 9 9 8 Ankyrin repeats (many copies) SH3_15 PF18346.1 KFR03991.1 - 6.1e-44 148.2 5.8 1.5e-21 76.5 0.0 3.6 4 0 0 4 4 4 2 Mind bomb SH3 repeat domain Ank PF00023.30 KFR03991.1 - 8.8e-41 136.6 12.7 3.9e-08 33.4 0.9 9.2 8 1 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.6 KFR03991.1 - 2.2e-29 98.2 16.1 0.00058 20.1 0.3 10.5 12 0 0 12 12 10 6 Ankyrin repeat MIB_HERC2 PF06701.13 KFR03991.1 - 1.4e-28 98.9 4.8 1.4e-28 98.9 4.8 3.7 4 0 0 4 4 4 1 Mib_herc2 zf-C3HC4_3 PF13920.6 KFR03991.1 - 2.8e-27 94.3 59.7 1.8e-10 40.5 7.9 4.7 4 1 0 4 4 4 3 Zinc finger, C3HC4 type (RING finger) ZZ PF00569.17 KFR03991.1 - 2.5e-11 43.2 8.4 2.5e-11 43.2 8.4 3.6 3 0 0 3 3 2 1 Zinc finger, ZZ type zf-C3HC4_2 PF13923.6 KFR03991.1 - 2.7e-08 33.5 9.8 2.7e-08 33.5 9.8 4.7 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFR03991.1 - 0.00058 19.7 55.8 0.0095 15.8 8.3 5.1 4 1 1 5 5 4 3 Prokaryotic RING finger family 4 GATA PF00320.27 KFR03992.1 - 3e-31 106.7 15.7 8.3e-16 57.3 4.4 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KFR03992.1 - 2.4e-08 33.3 5.6 0.00049 19.6 0.4 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 KFR03992.1 - 0.01 15.9 4.7 0.66 10.1 0.2 3.1 2 1 2 4 4 4 0 Zinc ribbon domain Auto_anti-p27 PF06677.12 KFR03992.1 - 0.02 15.1 5.2 0.46 10.7 0.4 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 KFR03992.1 - 0.047 13.6 5.3 3.1 7.7 0.2 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Elf1 PF05129.13 KFR03992.1 - 0.092 12.8 4.7 3.9 7.6 0.0 2.9 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.11 KFR03992.1 - 0.12 12.4 0.3 0.12 12.4 0.3 3.4 3 1 0 3 3 3 0 Putative transposase DNA-binding domain DZR PF12773.7 KFR03992.1 - 0.13 12.3 9.5 2.9 8.0 0.4 3.3 1 1 2 3 3 3 0 Double zinc ribbon Cytochrom_c3_2 PF14537.6 KFR03992.1 - 0.55 10.7 6.4 0.32 11.5 2.3 2.5 2 1 0 2 2 2 0 Cytochrome c3 zf-CHY PF05495.12 KFR03992.1 - 0.64 10.6 5.7 12 6.5 0.1 2.6 3 0 0 3 3 3 0 CHY zinc finger DUF2387 PF09526.10 KFR03992.1 - 0.81 9.9 5.4 15 5.9 0.3 3.2 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) OTT_1508_deam PF14441.6 KFR03992.1 - 1.2 9.1 4.1 12 5.9 0.0 2.5 2 1 0 2 2 2 0 OTT_1508-like deaminase Prim_Zn_Ribbon PF08273.12 KFR03992.1 - 2.7 8.3 9.8 1.4 9.3 2.8 2.6 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase C1_2 PF03107.16 KFR03992.1 - 3.7 7.9 7.3 20 5.6 1.0 3.2 2 2 0 2 2 2 0 C1 domain NUDE_C PF04880.13 KFR03992.1 - 4 7.9 7.7 7.2 7.0 7.7 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Tnp_zf-ribbon_2 PF13842.6 KFR03992.1 - 7 7.6 8.2 6.7 7.6 0.9 3.1 2 1 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon CtIP_N PF10482.9 KFR03993.1 - 9.8e-51 170.8 21.2 9.8e-51 170.8 21.2 2.4 2 0 0 2 2 2 1 Tumour-suppressor protein CtIP N-terminal domain SAE2 PF08573.10 KFR03993.1 - 1.2e-05 26.4 0.4 1.2e-05 26.4 0.4 5.6 4 1 1 5 5 5 2 DNA repair protein endonuclease SAE2/CtIP C-terminus Cob_adeno_trans PF01923.18 KFR03993.1 - 0.15 12.2 3.5 0.46 10.6 3.5 1.9 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF3450 PF11932.8 KFR03993.1 - 3.4 6.9 13.3 0.62 9.3 5.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) ZapB PF06005.12 KFR03993.1 - 4.3 7.9 28.6 0.13 12.7 4.8 3.6 3 0 0 3 3 3 0 Cell division protein ZapB FapA PF03961.13 KFR03993.1 - 7.6 5.0 18.3 2.2 6.8 8.0 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A Cyclin_N PF00134.23 KFR03994.1 - 5e-08 32.7 0.2 7e-08 32.3 0.2 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain TPT PF03151.16 KFR03995.1 - 2.6e-07 30.3 2.8 3.4e-07 29.9 2.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family TssN PF17555.2 KFR03995.1 - 0.67 9.3 4.3 0.25 10.7 1.9 1.6 1 1 0 1 1 1 0 Type VI secretion system, TssN EamA PF00892.20 KFR03995.1 - 0.67 10.1 16.5 0.64 10.2 6.6 2.3 2 0 0 2 2 2 0 EamA-like transporter family RIO1 PF01163.22 KFR03996.1 - 1.8e-75 252.7 0.3 4.3e-75 251.5 0.3 1.6 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 KFR03996.1 - 0.00039 19.9 0.2 0.00094 18.6 0.2 1.6 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KFR03996.1 - 0.0014 18.0 0.2 0.0053 16.1 0.2 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFR03996.1 - 0.026 14.1 0.1 0.065 12.8 0.1 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 KFR03996.1 - 0.047 13.6 0.2 0.81 9.6 0.2 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Mic1 PF07035.12 KFR03997.1 - 1e-70 236.5 0.9 1e-70 236.5 0.9 1.9 2 0 0 2 2 2 1 Colon cancer-associated protein Mic1-like Patched PF02460.18 KFR03998.1 - 3.1e-84 283.6 25.9 2.8e-83 280.4 26.3 2.1 2 1 0 2 2 2 1 Patched family NPC1_N PF16414.5 KFR03998.1 - 1.2e-79 267.3 4.9 1.2e-79 267.3 4.9 1.9 2 0 0 2 2 2 1 Niemann-Pick C1 N terminus Sterol-sensing PF12349.8 KFR03998.1 - 4.4e-57 192.2 6.6 4.4e-57 192.2 6.6 2.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 KFR03998.1 - 5.7e-05 22.2 3.1 5.7e-05 22.2 3.1 2.3 2 0 0 2 2 2 1 MMPL family ACR_tran PF00873.19 KFR03998.1 - 0.0002 19.2 8.1 0.0002 19.2 8.1 2.1 2 1 0 2 2 2 1 AcrB/AcrD/AcrF family Ank_2 PF12796.7 KFR03999.1 - 2.1e-49 166.0 1.3 1.6e-11 44.6 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFR03999.1 - 3.1e-48 161.6 5.5 1.3e-08 35.2 0.0 6.3 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KFR03999.1 - 1e-33 114.3 7.4 9.1e-06 25.9 0.0 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 KFR03999.1 - 1.6e-31 107.9 6.2 4.1e-09 36.5 0.0 7.9 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFR03999.1 - 9.9e-31 102.4 0.9 0.0027 18.1 0.0 8.2 8 0 0 8 8 8 6 Ankyrin repeat NIT PF08376.10 KFR03999.1 - 0.058 13.9 0.2 0.42 11.0 0.1 2.2 2 1 0 2 2 2 0 Nitrate and nitrite sensing Laminin_EGF PF00053.24 KFR04000.1 - 5.6e-97 317.8 309.7 4.5e-10 39.5 11.3 16.7 16 1 1 17 17 16 15 Laminin EGF domain Laminin_G_2 PF02210.24 KFR04000.1 - 1.5e-80 268.0 0.0 2.3e-24 86.4 0.0 5.5 5 0 0 5 5 5 5 Laminin G domain Laminin_N PF00055.17 KFR04000.1 - 2.5e-68 230.2 0.0 2.5e-68 230.2 0.0 2.9 3 0 0 3 3 1 1 Laminin N-terminal (Domain VI) Laminin_G_1 PF00054.23 KFR04000.1 - 3.8e-62 208.3 0.6 1.9e-20 73.4 0.0 6.3 6 1 0 6 6 6 4 Laminin G domain Laminin_I PF06008.14 KFR04000.1 - 2e-52 178.5 31.9 2e-52 178.5 31.9 3.7 2 1 1 4 4 4 1 Laminin Domain I Laminin_II PF06009.12 KFR04000.1 - 3.7e-36 124.2 0.2 3.7e-36 124.2 0.2 5.6 2 1 2 5 5 5 1 Laminin Domain II Laminin_B PF00052.18 KFR04000.1 - 1.1e-30 106.3 0.0 3.2e-30 104.8 0.0 1.9 1 0 0 1 1 1 1 Laminin B (Domain IV) Laminin_G_3 PF13385.6 KFR04000.1 - 2e-18 67.0 0.2 4.9e-07 30.0 0.0 4.4 4 0 0 4 4 4 2 Concanavalin A-like lectin/glucanases superfamily Activator-TraM PF11657.8 KFR04000.1 - 0.0012 18.7 3.4 0.0032 17.3 3.4 1.8 1 0 0 1 1 1 1 Transcriptional activator TraM Polysacc_lyase PF14099.6 KFR04000.1 - 0.1 12.5 0.0 19 5.0 0.0 2.5 2 0 0 2 2 2 0 Polysaccharide lyase DUF16 PF01519.16 KFR04000.1 - 2.8 8.5 32.7 0.12 12.9 2.0 5.0 4 1 1 5 5 5 0 Protein of unknown function DUF16 T3SchapCesA PF11439.8 KFR04000.1 - 3.6 7.8 6.9 19 5.5 0.1 3.5 3 0 0 3 3 3 0 Type III secretion system filament chaperone CesA DUF3808 PF10300.9 KFR04001.1 - 1.5e-125 419.7 6.8 1.7e-125 419.5 6.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Cohesin_load PF10345.9 KFR04001.1 - 3.4e-07 29.1 1.0 3.4e-07 29.1 1.0 1.6 2 0 0 2 2 2 1 Cohesin loading factor TPR_2 PF07719.17 KFR04001.1 - 2.8e-05 23.9 0.9 0.39 10.9 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFR04001.1 - 0.00018 21.2 0.6 0.32 10.9 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFR04001.1 - 0.0024 18.4 0.0 25 5.8 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFR04001.1 - 0.0047 17.2 0.2 1.7 9.0 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat VEFS-Box PF09733.9 KFR04001.1 - 0.02 14.7 0.1 0.056 13.2 0.1 1.8 1 0 0 1 1 1 0 VEFS-Box of polycomb protein TPR_7 PF13176.6 KFR04001.1 - 0.045 13.8 0.1 0.45 10.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat P3A PF08727.11 KFR04002.1 - 2.9 7.4 4.9 10 5.6 4.9 1.9 1 1 0 1 1 1 0 Poliovirus 3A protein like Oxysterol_BP PF01237.18 KFR04003.1 - 6.7e-151 502.3 0.5 9.2e-151 501.9 0.5 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein Ank PF00023.30 KFR04003.1 - 6.7e-23 80.1 3.9 5.5e-08 32.9 0.0 4.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 KFR04003.1 - 8e-22 77.6 1.7 2.4e-13 50.5 0.1 2.9 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFR04003.1 - 7.4e-21 73.9 3.5 6.3e-09 35.9 0.2 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFR04003.1 - 2.8e-19 69.2 1.7 3.9e-05 24.1 0.0 4.6 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFR04003.1 - 1.6e-15 55.7 0.6 5.1e-05 23.4 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat PH_11 PF15413.6 KFR04003.1 - 0.0045 17.4 0.2 0.0045 17.4 0.2 3.8 4 0 0 4 4 4 1 Pleckstrin homology domain PH PF00169.29 KFR04003.1 - 0.01 16.3 0.7 0.01 16.3 0.7 3.2 3 0 0 3 3 3 0 PH domain UPF0029 PF01205.19 KFR04004.1 - 4.6e-35 120.1 0.0 7e-35 119.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KFR04004.1 - 1.9e-16 60.4 1.0 1.9e-16 60.4 1.0 1.8 2 1 0 2 2 2 1 RWD domain DUF677 PF05055.12 KFR04004.1 - 0.14 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) 7tm_1 PF00001.21 KFR04005.1 - 1.6e-59 201.4 11.3 1.9e-59 201.1 11.3 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF5381 PF17353.2 KFR04005.1 - 0.21 11.4 1.5 19 5.0 0.0 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5381) 7tm_1 PF00001.21 KFR04006.1 - 3.5e-60 203.6 11.1 4.1e-60 203.3 11.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR04006.1 - 9e-05 22.0 15.1 0.0011 18.4 15.1 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF5381 PF17353.2 KFR04006.1 - 0.12 12.1 1.6 18 5.0 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5381) DUF1772 PF08592.11 KFR04006.1 - 4.6 7.6 0.0 4.6 7.6 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) SO_alpha_A3 PF17806.1 KFR04007.1 - 0.097 13.0 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Sarcosine oxidase A3 domain zf-C2H2_4 PF13894.6 KFR04008.1 - 2.5e-68 220.7 213.5 0.00037 21.1 0.8 31.2 31 0 0 31 31 31 26 C2H2-type zinc finger zf-C2H2 PF00096.26 KFR04008.1 - 1.5e-49 163.8 218.9 0.0012 19.2 3.0 30.6 31 0 0 31 31 31 23 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFR04008.1 - 8.8e-34 114.9 181.2 9e-08 31.9 0.1 26.5 26 1 1 27 27 26 15 C2H2-type zinc finger zf-Di19 PF05605.12 KFR04008.1 - 6.8e-22 77.5 168.5 6.5e-05 23.1 3.4 19.3 15 3 4 20 20 20 12 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KFR04008.1 - 2.1e-19 69.0 188.1 6.7e-06 26.3 1.0 28.6 32 1 0 32 32 31 13 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFR04008.1 - 4.4e-10 39.6 182.0 0.013 15.7 0.6 25.9 29 0 0 29 29 28 12 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFR04008.1 - 2e-05 24.8 168.7 0.11 12.9 0.9 24.5 8 6 13 22 22 22 11 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFR04008.1 - 0.00014 22.1 14.1 0.0079 16.6 1.2 21.5 25 0 0 25 25 25 8 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFR04008.1 - 0.01 16.1 1.6 0.01 16.1 1.6 13.9 9 4 4 14 14 14 0 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 KFR04008.1 - 0.063 13.2 0.1 0.063 13.2 0.1 16.8 18 1 1 19 19 18 0 zinc-finger of a C2HC-type Zn-C2H2_12 PF18112.1 KFR04008.1 - 0.11 13.0 0.2 0.11 13.0 0.2 11.2 13 0 0 13 13 10 0 Autophagy receptor zinc finger-C2H2 domain TAFH PF07531.14 KFR04011.1 - 8.3e-40 134.8 4.0 2.7e-39 133.2 4.0 2.0 1 0 0 1 1 1 1 NHR1 homology to TAF TAF4 PF05236.14 KFR04011.1 - 1.7e-33 116.6 1.5 2.7e-33 115.9 1.5 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family BTB_2 PF02214.22 KFR04012.1 - 2.5e-17 63.0 0.0 4e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain MIP PF00230.20 KFR04014.1 - 1.2e-72 244.4 14.5 1.5e-72 244.0 14.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein Sulfotransfer_2 PF03567.14 KFR04015.1 - 3.2e-61 207.4 1.9 4.1e-61 207.1 1.9 1.1 1 0 0 1 1 1 1 Sulfotransferase family Cadherin PF00028.17 KFR04017.1 - 2.8e-91 300.1 1.3 5.2e-23 81.3 0.1 5.8 6 0 0 6 6 6 5 Cadherin domain Cadherin_C PF01049.17 KFR04017.1 - 1.5e-53 181.0 0.4 2.9e-53 180.1 0.4 1.4 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_pro PF08758.11 KFR04017.1 - 4.7e-30 103.6 0.1 4.8e-29 100.4 0.1 2.4 2 0 0 2 2 2 1 Cadherin prodomain like Cadherin_3 PF16184.5 KFR04017.1 - 7e-07 29.2 5.6 0.035 14.1 0.1 4.7 4 0 0 4 4 4 2 Cadherin-like Cadherin_2 PF08266.12 KFR04017.1 - 7.7e-05 22.4 0.0 3.8 7.4 0.0 3.4 3 0 0 3 3 3 2 Cadherin-like He_PIG PF05345.12 KFR04017.1 - 0.00032 20.8 9.6 0.89 9.8 0.4 5.9 5 1 0 5 5 5 2 Putative Ig domain Cadherin_4 PF17803.1 KFR04017.1 - 0.013 16.1 20.1 0.66 10.6 0.1 5.0 5 0 0 5 5 4 0 Bacterial cadherin-like domain EphA2_TM PF14575.6 KFR04017.1 - 0.016 16.1 0.0 0.035 15.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Prok-E2_A PF14457.6 KFR04017.1 - 0.017 14.7 0.2 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic E2 family A DUF5385 PF17359.2 KFR04017.1 - 0.097 12.2 0.2 0.22 11.1 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Stevor PF17410.2 KFR04017.1 - 0.14 11.7 0.1 0.21 11.1 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4381 PF14316.6 KFR04017.1 - 0.19 12.0 0.1 0.34 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Big_9 PF17963.1 KFR04017.1 - 3.6 8.4 23.4 0.31 11.8 0.2 5.1 4 1 1 5 5 5 0 Bacterial Ig domain DUF4462 PF14692.6 KFR04019.1 - 0.17 11.4 0.8 0.41 10.2 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) Cadherin PF00028.17 KFR04021.1 - 3.7e-62 206.8 0.1 5.5e-14 52.4 0.0 6.0 6 0 0 6 6 6 5 Cadherin domain Cadherin_pro PF08758.11 KFR04021.1 - 6.6e-18 64.7 0.3 5.4e-17 61.7 0.2 2.5 2 0 0 2 2 2 1 Cadherin prodomain like Cadherin_C PF01049.17 KFR04021.1 - 6.1e-08 33.1 0.1 1.4e-07 31.9 0.1 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.12 KFR04021.1 - 6.2e-05 22.8 0.0 0.19 11.6 0.0 3.6 4 0 0 4 4 4 2 Cadherin-like Homeobox_KN PF05920.11 KFR04047.1 - 1.2e-15 57.2 0.4 1.2e-15 57.2 0.4 1.9 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 KFR04047.1 - 7.1e-07 29.0 0.2 1.3e-06 28.2 0.2 1.4 1 0 0 1 1 1 1 Homeodomain Dicty_REP PF05086.12 KFR04047.1 - 0.0048 15.0 0.4 0.0067 14.5 0.4 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein MRP-S32 PF10210.9 KFR04047.1 - 0.56 10.8 3.3 0.61 10.7 0.2 2.3 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S32 WD40 PF00400.32 KFR04049.1 - 4.8e-41 138.0 28.3 0.0004 21.1 1.6 12.9 13 0 0 13 13 13 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR04049.1 - 2.5e-05 24.5 4.1 2.1 8.7 0.1 6.7 4 1 4 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain bHLH-MYC_N PF14215.6 KFR04049.1 - 0.035 14.4 0.1 0.11 12.8 0.1 1.8 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal eIF2A PF08662.11 KFR04049.1 - 0.079 12.8 4.8 6 6.7 0.2 4.0 3 2 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KFR04049.1 - 7.6 6.6 9.0 80 3.3 0.1 4.9 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Vinculin PF01044.19 KFR04050.1 - 8.8e-53 179.8 21.9 4.4e-32 111.3 8.0 3.5 2 1 2 4 4 4 3 Vinculin family COG5 PF10392.9 KFR04050.1 - 0.67 10.1 9.6 0.29 11.3 2.9 3.6 3 2 1 4 4 4 0 Golgi transport complex subunit 5 WXG100 PF06013.12 KFR04050.1 - 1.5 9.1 9.1 0.066 13.5 1.2 3.0 4 0 0 4 4 4 0 Proteins of 100 residues with WXG GCV_H PF01597.19 KFR04051.1 - 6e-08 32.6 0.0 1e-07 31.8 0.0 1.4 2 0 0 2 2 2 1 Glycine cleavage H-protein Zip PF02535.22 KFR04052.1 - 1.6e-97 326.7 21.6 1.6e-97 326.7 21.6 3.0 2 2 0 2 2 2 1 ZIP Zinc transporter Kazal_2 PF07648.15 KFR04053.1 - 6.6e-21 74.2 18.5 8.2e-11 41.9 5.8 3.4 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFR04053.1 - 8.6e-13 48.1 29.4 1.1e-06 28.6 11.7 3.5 2 1 1 3 3 3 2 Kazal-type serine protease inhibitor domain DUF3844 PF12955.7 KFR04053.1 - 0.0042 17.2 1.8 0.0042 17.2 1.8 3.4 2 1 1 3 3 3 1 Domain of unknown function (DUF3844) EphA2_TM PF14575.6 KFR04053.1 - 0.012 16.4 0.3 0.037 14.9 0.3 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain GRA6 PF05084.13 KFR04053.1 - 0.11 12.4 0.6 0.21 11.6 0.0 1.7 2 0 0 2 2 2 0 Granule antigen protein (GRA6) PTRF_SDPR PF15237.6 KFR04054.1 - 2e-93 312.5 18.1 3.1e-93 311.9 18.1 1.2 1 0 0 1 1 1 1 PTRF/SDPR family DUF1664 PF07889.12 KFR04054.1 - 0.0045 17.0 7.3 0.0045 17.0 7.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) MCPsignal PF00015.21 KFR04054.1 - 0.48 10.2 16.2 0.077 12.8 2.9 2.9 2 2 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 KFR04054.1 - 0.7 10.2 5.9 3.4 8.0 4.7 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Hormone_1 PF00103.20 KFR04054.1 - 3.3 7.4 7.2 3.6 7.3 1.1 2.9 2 1 1 3 3 3 0 Somatotropin hormone family DnaB_C PF03796.15 KFR04054.1 - 6.7 6.0 14.3 0.6 9.4 9.0 1.8 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain DHC_N1 PF08385.12 KFR04055.1 - 9e-56 189.7 2.3 9.9e-56 189.5 2.3 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 Proteasom_PSMB PF10508.9 KFR04055.1 - 0.039 12.5 0.2 0.069 11.6 0.2 1.4 1 1 0 1 1 1 0 Proteasome non-ATPase 26S subunit DCX PF03607.17 KFR04055.1 - 0.056 13.6 0.9 4.4 7.5 0.2 2.7 2 1 0 2 2 2 0 Doublecortin Rab5-bind PF09311.11 KFR04055.1 - 0.093 12.1 1.5 0.13 11.6 1.5 1.2 1 0 0 1 1 1 0 Rabaptin-like protein FerA PF08165.11 KFR04055.1 - 0.49 10.4 2.6 3.2 7.8 0.1 2.8 3 0 0 3 3 3 0 FerA (NUC095) domain Sec6 PF06046.13 KFR04056.1 - 3.6e-159 530.8 14.2 3.6e-159 530.8 14.2 1.5 2 0 0 2 2 2 1 Exocyst complex component Sec6 Ago_N_1 PF18351.1 KFR04056.1 - 0.0088 16.4 1.0 0.054 13.9 0.0 2.8 2 1 1 3 3 3 1 Fungal Argonaute N-terminal domain Bcl-2 PF00452.19 KFR04056.1 - 0.12 13.0 0.1 0.82 10.4 0.1 2.5 1 1 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family Tma16 PF11176.8 KFR04056.1 - 0.17 11.8 3.1 6.1 6.7 0.5 3.3 2 0 0 2 2 2 0 Translation machinery-associated protein 16 EF-hand_7 PF13499.6 KFR04057.1 - 1.6e-24 86.1 2.8 3.1e-11 43.6 0.7 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KFR04057.1 - 4.2e-22 76.0 11.9 3.2e-07 29.4 0.1 5.3 5 1 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 KFR04057.1 - 4.8e-21 72.8 5.6 4.6e-07 29.3 0.1 5.2 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.6 KFR04057.1 - 4.9e-20 71.1 3.6 2e-06 27.6 0.1 4.7 2 2 3 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.6 KFR04057.1 - 1.1e-12 46.9 3.7 0.00036 19.9 0.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 KFR04057.1 - 0.0056 17.0 0.0 0.64 10.4 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain WWE PF02825.20 KFR04057.1 - 0.011 16.4 0.3 0.42 11.2 0.2 2.5 2 1 0 2 2 2 0 WWE domain EF-hand_2 PF09068.11 KFR04057.1 - 0.064 13.4 0.0 3.2 7.9 0.0 2.5 2 1 0 2 2 2 0 EF hand Alpha_adaptin_C PF02296.16 KFR04057.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain PAS PF00989.25 KFR04059.1 - 7.2e-11 42.1 0.0 1.5e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 KFR04059.1 - 8.1e-06 26.0 0.5 0.012 15.9 0.1 2.5 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 KFR04059.1 - 1.4e-05 25.0 0.1 3.3e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_11 PF14598.6 KFR04059.1 - 3.7e-05 23.8 0.2 0.0016 18.6 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS_9 PF13426.7 KFR04059.1 - 0.0035 17.6 0.0 0.013 15.8 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 KFR04059.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 PAS fold zf-C2H2_jaz PF12171.8 KFR04060.1 - 0.00032 20.9 1.3 0.00032 20.9 1.3 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFR04060.1 - 0.001 19.4 2.2 0.001 19.4 2.2 3.5 3 1 0 3 3 3 1 Zinc-finger of C2H2 type PNISR PF15996.5 KFR04060.1 - 0.23 11.7 18.5 0.46 10.7 18.5 1.5 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Ipi1_N PF12333.8 KFR04061.1 - 2.6e-23 82.6 1.1 2.6e-23 82.6 1.1 3.6 4 0 0 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation Vac14_Fab1_bd PF12755.7 KFR04061.1 - 0.018 15.6 0.0 0.14 12.7 0.0 2.5 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KFR04061.1 - 0.038 14.5 0.1 0.87 10.2 0.0 3.3 3 0 0 3 3 3 0 HEAT-like repeat DUF2474 PF10617.9 KFR04061.1 - 1 9.2 4.5 3.3 7.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2474) Ank_2 PF12796.7 KFR04062.1 - 4e-80 264.5 8.7 1.1e-16 61.1 0.0 8.1 2 1 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFR04062.1 - 1.1e-59 198.0 19.0 9.8e-11 42.0 0.1 11.6 5 2 6 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFR04062.1 - 8.3e-55 176.3 15.6 0.00043 20.5 0.0 15.0 15 0 0 15 15 15 11 Ankyrin repeat Ank PF00023.30 KFR04062.1 - 8.9e-55 180.9 21.2 4e-05 23.9 0.1 14.8 15 0 0 15 15 15 13 Ankyrin repeat Ank_5 PF13857.6 KFR04062.1 - 3.7e-52 173.7 18.2 1.1e-09 38.3 0.1 11.8 6 3 6 12 12 12 10 Ankyrin repeats (many copies) IQ PF00612.27 KFR04062.1 - 3e-08 32.7 6.1 0.0031 17.1 0.3 2.9 2 0 0 2 2 2 2 IQ calmodulin-binding motif Thioredoxin_6 PF13848.6 KFR04063.1 - 2.7e-47 161.1 0.1 3.8e-43 147.6 0.1 2.4 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 KFR04063.1 - 3.3e-21 75.2 0.0 8.4e-21 73.9 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Calsequestrin PF01216.17 KFR04063.1 - 3.1e-07 29.8 0.1 5.3e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Calsequestrin OST3_OST6 PF04756.13 KFR04063.1 - 2.6e-05 23.7 0.0 4.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KFR04063.1 - 0.00045 20.6 0.1 0.0018 18.7 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain HyaE PF07449.11 KFR04063.1 - 0.00066 19.6 0.0 0.0021 18.0 0.0 1.8 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 KFR04063.1 - 0.0058 16.9 0.2 0.091 13.1 0.1 2.5 1 1 1 2 2 2 1 Thioredoxin-like SNARE PF05739.19 KFR04064.1 - 1.9e-06 27.8 0.2 3.7e-06 26.8 0.2 1.6 1 0 0 1 1 1 1 SNARE domain Phage_holin_3_6 PF07332.11 KFR04064.1 - 0.0088 16.1 1.4 0.023 14.7 1.4 1.8 1 1 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DUF585 PF04522.12 KFR04064.1 - 0.093 12.3 0.0 0.5 9.9 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF585) ThrE PF06738.12 KFR04064.1 - 0.15 11.5 0.2 0.5 9.7 0.0 1.8 2 0 0 2 2 2 0 Putative threonine/serine exporter SlyX PF04102.12 KFR04064.1 - 0.29 11.8 0.1 0.29 11.8 0.1 3.1 4 0 0 4 4 4 0 SlyX RVT_1 PF00078.27 KFR04065.1 - 0.21 11.1 0.0 0.4 10.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C4 PF00105.18 KFR04066.1 - 3.6e-31 107.4 18.3 6.4e-31 106.6 18.3 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFR04066.1 - 1.9e-19 70.1 0.0 3.3e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Sec61_beta PF03911.16 KFR04070.1 - 1.1e-19 70.2 0.0 1.4e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Sec61beta family OGFr_III PF04680.13 KFR04070.1 - 0.12 13.0 0.1 0.12 13.0 0.1 1.9 2 0 0 2 2 2 0 Opioid growth factor receptor repeat Glycos_transf_1 PF00534.20 KFR04071.1 - 1e-38 132.6 0.0 1.5e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFR04071.1 - 3.8e-18 66.2 0.0 5.8e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFR04071.1 - 4.3e-05 23.6 0.1 8.8e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KFR04071.1 - 0.0005 20.4 0.0 0.0014 19.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 DUF1796 PF08795.10 KFR04071.1 - 0.012 15.6 0.6 0.59 10.1 0.6 2.7 1 1 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Glyco_trans_4_4 PF13579.6 KFR04071.1 - 0.043 14.2 0.1 0.12 12.8 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Ifi-6-16 PF06140.13 KFR04072.1 - 4e-21 74.7 22.7 2.6e-11 43.3 9.6 2.0 1 1 1 2 2 2 2 Interferon-induced 6-16 family CAP PF00188.26 KFR04073.1 - 2.4e-22 80.1 0.8 3.1e-22 79.8 0.8 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Spc29 PF17082.5 KFR04074.1 - 0.0088 15.9 0.1 0.011 15.6 0.1 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 BLOC1_2 PF10046.9 KFR04074.1 - 0.015 15.6 0.4 0.13 12.6 0.1 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1993 PF09351.10 KFR04074.1 - 0.024 14.8 0.0 0.17 12.0 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) AIP3 PF03915.13 KFR04074.1 - 0.043 12.9 0.3 0.072 12.2 0.3 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 FAP206 PF12018.8 KFR04074.1 - 0.07 12.6 0.0 0.079 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF5063 PF16702.5 KFR04074.1 - 0.085 13.2 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5063) SIX1_SD PF16878.5 KFR04074.1 - 0.086 13.4 0.0 0.15 12.6 0.0 1.4 1 1 0 1 1 1 0 Transcriptional regulator, SIX1, N-terminal SD domain FlaC_arch PF05377.11 KFR04074.1 - 0.11 12.9 0.8 7.2 7.1 0.8 2.6 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF16 PF01519.16 KFR04074.1 - 0.12 12.9 0.1 0.23 11.9 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 CLZ PF16526.5 KFR04074.1 - 0.12 12.7 0.0 11 6.5 0.0 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Sec8_exocyst PF04048.14 KFR04074.1 - 0.13 12.1 0.2 0.16 11.9 0.2 1.1 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Laminin_I PF06008.14 KFR04074.1 - 0.14 11.8 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 Laminin Domain I PDZ PF00595.24 KFR04075.1 - 1.4e-10 41.4 0.0 2.1e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PB1 PF00564.24 KFR04075.1 - 1.4e-10 40.9 0.0 3.2e-10 39.8 0.0 1.6 2 0 0 2 2 2 1 PB1 domain PDZ_6 PF17820.1 KFR04075.1 - 3.3e-09 36.4 0.0 6.4e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFR04075.1 - 0.12 12.7 0.1 0.26 11.6 0.1 1.5 1 0 0 1 1 1 0 PDZ domain CARMIL_C PF16000.5 KFR04076.1 - 9.2e-107 357.2 12.5 9.2e-107 357.2 12.5 3.1 2 1 0 2 2 2 1 CARMIL C-terminus Carm_PH PF17888.1 KFR04076.1 - 9.9e-23 80.3 0.0 2.5e-22 79.0 0.0 1.8 1 0 0 1 1 1 1 Carmil pleckstrin homology domain LRR_6 PF13516.6 KFR04076.1 - 5.4e-10 38.5 28.7 0.0022 17.9 0.1 8.6 10 0 0 10 10 10 5 Leucine Rich repeat LRR_4 PF12799.7 KFR04076.1 - 0.0039 17.6 26.2 2.7 8.5 1.1 6.6 3 2 4 8 8 8 5 Leucine Rich repeats (2 copies) IL34 PF15036.6 KFR04076.1 - 0.053 13.6 0.3 0.15 12.1 0.3 1.8 1 0 0 1 1 1 0 Interleukin 34 Ribosomal_L34 PF00468.17 KFR04076.1 - 0.17 11.9 0.7 2.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L34 LRR_1 PF00560.33 KFR04076.1 - 1.3 9.9 17.6 82 4.4 0.3 7.8 8 0 0 8 8 8 0 Leucine Rich Repeat PL48 PF15903.5 KFR04077.1 - 5.9e-175 581.3 0.4 9.6e-175 580.6 0.4 1.3 1 0 0 1 1 1 1 Filopodia upregulated, FAM65 HEAT_2 PF13646.6 KFR04077.1 - 6.4e-06 26.5 2.6 3e-05 24.3 0.1 2.9 2 1 1 3 3 3 1 HEAT repeats Arm PF00514.23 KFR04077.1 - 0.011 15.8 3.9 2.1 8.5 0.0 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HR1 PF02185.16 KFR04077.1 - 0.088 12.9 0.1 0.088 12.9 0.1 2.7 3 0 0 3 3 3 0 Hr1 repeat GvpD PF07088.11 KFR04077.1 - 0.1 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein SHE3 PF17078.5 KFR04077.1 - 0.13 12.0 4.0 0.49 10.1 4.0 2.1 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Geminin PF07412.12 KFR04078.1 - 1.7e-83 279.2 13.9 1.9e-83 279.1 13.9 1.0 1 0 0 1 1 1 1 Geminin Phage_GPO PF05929.11 KFR04078.1 - 0.00046 19.9 2.6 0.00062 19.5 2.6 1.1 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase UPF0242 PF06785.11 KFR04078.1 - 0.0025 17.9 9.3 0.0042 17.2 9.2 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 KFR04078.1 - 0.015 15.1 1.4 0.015 15.1 1.4 1.8 2 0 0 2 2 2 0 Septum formation initiator Laminin_II PF06009.12 KFR04078.1 - 0.018 15.1 3.3 0.018 15.1 3.3 1.8 2 0 0 2 2 2 0 Laminin Domain II Csm1_N PF18504.1 KFR04078.1 - 0.033 14.5 3.0 0.033 14.5 3.0 2.4 1 1 0 2 2 2 0 Csm1 N-terminal domain FapA PF03961.13 KFR04078.1 - 0.055 12.1 3.4 0.061 11.9 3.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A XLF PF09302.11 KFR04078.1 - 0.18 12.0 5.5 0.31 11.2 1.2 2.2 1 1 1 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF641 PF04859.12 KFR04078.1 - 0.68 10.3 9.1 0.5 10.7 4.2 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF5094 PF17015.5 KFR04078.1 - 1 9.4 9.0 2.6 8.1 9.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5094) DUF5101 PF17031.5 KFR04078.1 - 1.1 9.4 10.1 0.083 13.0 2.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF5101) CCDC-167 PF15188.6 KFR04078.1 - 3.4 8.1 11.4 3.9 7.9 9.6 2.2 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF4566 PF15130.6 KFR04079.1 - 1.2e-138 459.9 2.2 1.3e-138 459.7 2.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4566) 4HBT PF03061.22 KFR04080.1 - 4e-14 52.7 0.1 6.2e-14 52.1 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KFR04080.1 - 1.1e-05 25.8 0.1 1.4e-05 25.5 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.6 KFR04080.1 - 0.0095 16.1 0.2 0.05 13.7 0.1 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4442) UBA_4 PF14555.6 KFR04081.1 - 2.1e-11 43.5 0.0 4.3e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain Exo_endo_phos PF03372.23 KFR04081.1 - 3.4e-07 30.0 0.0 5.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family 7tm_1 PF00001.21 KFR04082.1 - 1.3e-57 195.2 15.5 1.5e-57 194.9 15.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR04082.1 - 1.2e-08 34.6 13.4 1.6e-08 34.3 13.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 KFR04082.1 - 2.7e-08 33.5 13.8 6.3e-06 25.7 13.8 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 KFR04082.1 - 3.4e-05 23.3 12.1 4.4e-05 23.0 12.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFR04082.1 - 6.6e-05 22.8 13.9 0.00015 21.6 13.9 1.5 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srd PF10317.9 KFR04082.1 - 7.5e-05 22.1 19.1 0.0042 16.3 19.1 2.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd Chitin_synth_1 PF01644.17 KFR04082.1 - 0.019 14.9 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Chitin synthase Bac_rhodopsin PF01036.18 KFR04082.1 - 0.16 11.5 11.9 0.11 12.0 5.4 2.4 2 1 0 2 2 2 0 Bacteriorhodopsin-like protein Myelin_MBP PF01669.17 KFR04083.1 - 2e-70 236.3 11.4 3.1e-70 235.7 11.4 1.3 1 0 0 1 1 1 1 Myelin basic protein zf-C2H2 PF00096.26 KFR04084.1 - 5e-26 89.7 90.0 0.00026 21.2 7.8 10.7 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR04084.1 - 1.2e-18 66.1 86.4 0.0048 17.6 0.7 10.8 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFR04084.1 - 7.6e-09 35.6 2.2 7.6e-09 35.6 2.2 12.9 14 1 0 14 14 14 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFR04084.1 - 2.6e-06 27.1 2.0 2.6e-06 27.1 2.0 8.2 9 0 0 9 9 9 4 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KFR04084.1 - 3.7e-06 27.1 32.5 0.6 10.4 0.3 6.3 4 2 1 5 5 5 5 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 KFR04084.1 - 0.91 9.5 39.7 0.14 12.1 2.0 7.1 7 0 0 7 7 7 0 zinc-finger of a C2HC-type zf-C2H2_3rep PF18868.1 KFR04084.1 - 3.7 8.3 26.5 0.14 12.9 4.3 6.7 6 2 1 7 7 7 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 KFR04085.1 - 1.2e-12 48.0 20.2 0.0053 17.1 1.0 5.5 4 2 1 5 5 5 4 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KFR04085.1 - 1.3e-10 41.1 28.9 0.038 14.5 1.3 5.6 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR04085.1 - 1.1e-09 38.3 23.7 0.069 14.0 2.8 5.7 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFR04085.1 - 4.7e-05 23.3 21.8 0.024 14.6 2.4 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2HE PF16278.5 KFR04085.1 - 0.00034 21.0 11.9 2.4 8.7 0.0 6.0 5 0 0 5 5 5 2 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 KFR04085.1 - 0.0032 17.8 9.3 0.023 15.1 1.9 2.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF760 PF05542.11 KFR04085.1 - 0.026 14.9 0.3 0.46 10.9 0.0 3.2 4 0 0 4 4 3 0 Protein of unknown function (DUF760) zf-C2H2_jaz PF12171.8 KFR04085.1 - 0.043 14.1 0.8 0.043 14.1 0.8 4.8 5 0 0 5 5 4 0 Zinc-finger double-stranded RNA-binding Lar_restr_allev PF14354.6 KFR04085.1 - 0.046 14.1 1.7 16 6.0 0.0 4.5 6 0 0 6 6 6 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.10 KFR04085.1 - 0.059 13.5 11.1 6.4 7.0 0.1 5.4 5 0 0 5 5 5 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 KFR04085.1 - 0.071 13.0 1.8 0.075 13.0 0.2 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PyrI_C PF02748.15 KFR04085.1 - 0.4 10.6 2.1 4.1 7.4 0.1 3.2 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_11 PF16622.5 KFR04085.1 - 1.1 9.1 15.8 0.13 12.0 2.4 3.8 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 KFR04085.1 - 3.7 7.5 8.6 4.5 7.2 0.2 4.2 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) DUF678 PF05077.12 KFR04085.1 - 5.9 7.1 10.5 34 4.7 0.0 5.1 5 1 0 5 5 5 0 Protein of unknown function (DUF678) ADH_zinc_N PF00107.26 KFR04086.1 - 9.1e-27 93.6 0.0 1.6e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFR04086.1 - 2e-14 54.8 0.0 3e-13 51.0 0.0 2.3 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFR04086.1 - 5.7e-08 32.6 0.4 0.00017 21.5 0.0 3.3 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain PHB_acc_N PF07879.11 KFR04087.1 - 0.16 12.0 1.1 2.8 8.1 0.1 3.2 3 0 0 3 3 3 0 PHB/PHA accumulation regulator DNA-binding domain VPDSG-CTERM PF18205.1 KFR04087.1 - 3.7 7.5 4.7 2.3 8.1 0.9 2.3 2 0 0 2 2 2 0 VPDSG-CTERM motif zf-H2C2_2 PF13465.6 KFR04088.1 - 3.1e-09 36.8 113.2 3.5e-05 24.0 1.1 14.9 17 0 0 17 17 17 8 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFR04088.1 - 1.2e-05 25.0 4.1 1.2e-05 25.0 4.1 13.0 14 0 0 14 14 14 7 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KFR04088.1 - 0.00014 22.1 99.8 0.14 12.5 6.1 9.9 9 0 0 9 9 9 7 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KFR04088.1 - 0.00015 22.3 128.9 0.3 12.0 0.7 18.0 18 0 0 18 18 18 7 C2H2-type zinc finger zf-met PF12874.7 KFR04088.1 - 0.0052 17.1 2.4 0.0052 17.1 2.4 9.8 11 0 0 11 11 11 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFR04088.1 - 0.011 16.0 0.5 0.011 16.0 0.5 14.3 7 6 8 15 15 15 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KFR04088.1 - 0.021 15.2 1.6 0.021 15.2 1.6 18.2 19 0 0 19 19 19 0 Zinc finger, C2H2 type zf-LYAR PF08790.11 KFR04088.1 - 0.13 12.2 11.8 0.34 10.9 0.6 4.3 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Peptidase_M20 PF01546.28 KFR04089.1 - 2e-38 132.2 0.0 2.7e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFR04089.1 - 6.8e-12 45.3 0.0 1.3e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KFR04089.1 - 0.0068 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KFR04090.1 - 7.3e-36 123.8 0.0 1e-35 123.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFR04090.1 - 5.4e-15 55.2 0.0 9.4e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KFR04090.1 - 0.05 13.3 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 PIP49_C PF12260.8 KFR04091.1 - 3.4e-59 199.7 1.7 4.1e-59 199.4 0.7 1.6 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 PIP49_N PF14875.6 KFR04091.1 - 3.3e-11 43.3 0.7 5.5e-11 42.6 0.0 1.7 2 0 0 2 2 2 1 N-term cysteine-rich ER, FAM69 DUF4708 PF15813.5 KFR04092.1 - 2e-28 99.3 0.2 2.3e-28 99.1 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4708) Cyt-b5 PF00173.28 KFR04093.1 - 4.6e-08 33.1 0.0 6.4e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TIM21 PF08294.11 KFR04094.1 - 9.5e-50 168.2 0.2 1.3e-49 167.9 0.2 1.2 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 KFR04094.1 - 6.8e-07 29.0 0.0 1.7e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 F-box-like PF12937.7 KFR04095.1 - 1.2e-08 34.7 0.0 2.5e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFR04095.1 - 5.3e-07 29.4 0.0 5.3e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KFR04095.1 - 0.024 14.5 1.2 0.19 11.6 1.2 2.3 1 1 0 1 1 1 0 F-box CUB PF00431.20 KFR04096.1 - 1.3e-39 134.9 0.5 3.7e-26 91.6 0.0 2.7 3 0 0 3 3 3 2 CUB domain Ldl_recept_a PF00057.18 KFR04096.1 - 1.4e-07 31.6 2.4 1.4e-07 31.6 2.4 2.7 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A C1q PF00386.21 KFR04098.1 - 3.2e-28 98.5 0.3 3.9e-28 98.2 0.3 1.1 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 KFR04098.1 - 0.02 14.8 0.1 0.039 13.9 0.1 1.4 1 1 0 1 1 1 0 BclA C-terminal domain RVT_1 PF00078.27 KFR04099.1 - 1.9e-15 57.0 0.0 2.6e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFR04101.1 - 0.003 17.1 0.1 0.0052 16.3 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SH2 PF00017.24 KFR04103.1 - 1.9e-12 47.1 0.0 4.8e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.16 KFR04103.1 - 3.7e-11 43.2 2.6 4e-11 43.1 1.2 1.8 2 0 0 2 2 2 1 SOCS box RTTN_N PF14726.6 KFR04104.1 - 6.8e-30 103.7 13.6 1e-29 103.2 0.0 6.0 5 2 0 6 6 6 1 Rotatin, an armadillo repeat protein, centriole functioning V-set PF07686.17 KFR04105.1 - 2.5e-19 69.4 0.4 2e-08 34.4 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.6 KFR04105.1 - 5.2e-12 46.2 0.5 5.9e-07 30.0 0.2 2.6 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFR04105.1 - 1.8e-10 40.9 0.4 0.0013 18.8 0.1 3.2 2 2 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFR04105.1 - 5.2e-07 29.6 0.7 0.00014 21.8 0.3 2.6 2 2 0 2 2 2 2 Immunoglobulin I-set domain Izumo-Ig PF16706.5 KFR04105.1 - 0.044 13.8 0.0 5.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain IRS PF02174.17 KFR04106.1 - 3.5e-30 103.8 0.0 6e-30 103.1 0.0 1.4 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.29 KFR04106.1 - 0.0015 19.0 0.6 0.0029 18.1 0.6 1.5 1 0 0 1 1 1 1 PH domain CREPT PF16566.5 KFR04106.1 - 0.056 13.6 0.4 0.17 12.0 0.2 1.8 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour FtsL PF04999.13 KFR04107.1 - 6.5 6.8 9.3 6.7 6.8 2.8 2.6 2 0 0 2 2 2 0 Cell division protein FtsL Thioredoxin_6 PF13848.6 KFR04108.1 - 7.6e-28 97.7 0.1 1.6e-25 90.1 0.5 2.2 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 KFR04108.1 - 1.9e-25 88.8 0.0 1.9e-24 85.6 0.0 2.5 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_2 PF13098.6 KFR04108.1 - 0.00015 22.2 0.3 0.0021 18.5 0.1 2.9 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFR04108.1 - 0.0044 17.3 0.1 2.4 8.5 0.0 3.8 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin_7 PF13899.6 KFR04108.1 - 0.074 13.2 0.1 0.31 11.2 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like Transglut_C PF00927.22 KFR04109.1 - 1.1e-30 105.9 0.0 2.2e-17 63.1 0.0 2.6 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 KFR04109.1 - 1.1e-11 45.2 0.3 2.3e-11 44.1 0.3 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Sulfotransfer_1 PF00685.27 KFR04111.1 - 2.5e-10 40.3 0.0 8.4e-09 35.3 0.0 3.2 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFR04111.1 - 1.6e-05 25.4 0.0 0.0017 18.8 0.0 3.2 3 0 0 3 3 3 1 Sulfotransferase family DUF4962 PF16332.5 KFR04111.1 - 7.1e-05 21.5 4.9 7.1e-05 21.5 4.9 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4962) Beta_helix PF13229.6 KFR04111.1 - 0.1 12.5 0.6 0.2 11.5 0.6 1.4 1 0 0 1 1 1 0 Right handed beta helix region DUF1195 PF06708.11 KFR04111.1 - 1.7 8.4 4.1 2.2 8.0 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1195) RVT_1 PF00078.27 KFR04112.1 - 0.0041 16.7 0.0 0.0052 16.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3299 PF11736.8 KFR04113.1 - 0.12 12.3 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3299) Cpta_toxin PF07254.12 KFR04113.1 - 0.26 11.3 1.9 1.7 8.6 0.1 2.2 1 1 1 2 2 2 0 Membrane-bound toxin component of toxin-antitoxin system Cadherin PF00028.17 KFR04114.1 - 2.8e-75 248.8 9.5 6.7e-18 64.9 0.1 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFR04114.1 - 1.4e-53 181.1 1.2 1.2e-52 178.1 0.7 2.4 2 0 0 2 2 2 1 Cadherin cytoplasmic region Cadherin_2 PF08266.12 KFR04114.1 - 3.7e-08 33.1 0.0 0.49 10.3 0.0 4.8 4 1 0 4 4 4 3 Cadherin-like Cadherin_3 PF16184.5 KFR04114.1 - 0.00022 21.2 8.3 3.9 7.5 0.0 5.6 6 0 0 6 6 6 2 Cadherin-like Big_9 PF17963.1 KFR04114.1 - 0.011 16.4 14.6 2.8 8.7 0.3 5.0 5 0 0 5 5 4 0 Bacterial Ig domain Cadherin_4 PF17803.1 KFR04114.1 - 0.051 14.2 16.8 0.26 11.9 0.8 5.1 5 0 0 5 5 5 0 Bacterial cadherin-like domain Herpes_UL82_83 PF05784.11 KFR04114.1 - 0.071 11.9 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Betaherpesvirus UL82/83 protein N terminus Phage_holin_3_6 PF07332.11 KFR04114.1 - 0.089 12.8 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4199 PF13858.6 KFR04114.1 - 0.12 12.8 0.4 0.24 11.8 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF2663 PF10864.8 KFR04114.1 - 0.12 12.7 0.3 23 5.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) FTCD_C PF04961.12 KFR04114.1 - 0.16 11.8 0.0 17 5.1 0.0 2.4 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase Invasin_D3 PF09134.10 KFR04114.1 - 0.73 10.2 6.5 49 4.3 0.0 4.8 6 0 0 6 6 6 0 Invasin, domain 3 zf-RanBP PF00641.18 KFR04187.1 - 1.3e-08 34.0 1.9 2.1e-08 33.4 1.9 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Maf1 PF09174.10 KFR04188.1 - 8e-65 218.2 0.0 1e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator BOP1NT PF08145.12 KFR04190.1 - 7.4e-105 350.5 4.7 7.4e-105 350.5 4.7 1.7 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.32 KFR04190.1 - 1.2e-23 82.9 5.7 3.2e-05 24.6 0.0 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR04190.1 - 0.023 15.0 0.1 3 8.2 0.0 3.5 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SOTI PF17079.5 KFR04190.1 - 0.11 12.9 0.5 7.7 7.0 0.0 2.7 3 0 0 3 3 3 0 Male-specific protein scotti HSF_DNA-bind PF00447.17 KFR04191.1 - 1.7e-26 92.6 1.4 2.5e-26 92.1 1.4 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding Keratin PF02422.16 KFR04198.1 - 2.3e-28 97.7 11.2 2.4e-28 97.6 11.2 1.0 1 0 0 1 1 1 1 Keratin Cornifin PF02389.15 KFR04198.1 - 0.013 15.7 8.7 0.014 15.6 8.7 1.0 1 0 0 1 1 1 0 Cornifin (SPRR) family DUF3432 PF11914.8 KFR04198.1 - 0.034 14.4 4.8 0.053 13.8 4.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.16 KFR04199.1 - 6e-32 109.2 6.9 6.6e-32 109.1 6.9 1.0 1 0 0 1 1 1 1 Keratin Cornifin PF02389.15 KFR04199.1 - 0.072 13.3 2.3 0.085 13.1 2.3 1.1 1 0 0 1 1 1 0 Cornifin (SPRR) family Keratin_2_head PF16208.5 KFR04199.1 - 0.27 11.4 19.1 0.3 11.2 19.1 1.1 1 0 0 1 1 1 0 Keratin type II head Keratin PF02422.16 KFR04200.1 - 8.3e-34 115.2 10.1 1.2e-33 114.6 10.1 1.3 1 1 0 1 1 1 1 Keratin Keratin_2_head PF16208.5 KFR04200.1 - 9.8 6.3 28.9 12 6.0 28.9 1.1 1 0 0 1 1 1 0 Keratin type II head Keratin PF02422.16 KFR04201.1 - 2e-27 94.7 10.9 2.1e-27 94.6 10.9 1.0 1 0 0 1 1 1 1 Keratin S_100 PF01023.19 KFR04202.1 - 2.2e-19 68.9 0.1 3e-19 68.4 0.1 1.2 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.32 KFR04202.1 - 0.00053 19.3 0.8 0.0018 17.7 0.2 2.2 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KFR04202.1 - 0.0023 18.3 0.6 0.0041 17.5 0.6 1.5 1 1 0 1 1 1 1 EF-hand domain pair DEK_C PF08766.11 KFR04202.1 - 0.01 15.8 1.1 0.022 14.7 1.1 1.5 1 0 0 1 1 1 1 DEK C terminal domain DUF5421 PF17458.2 KFR04202.1 - 0.18 11.2 5.4 0.19 11.1 5.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5421) S_100 PF01023.19 KFR04204.1 - 1.9e-20 72.3 0.3 3.8e-20 71.3 0.3 1.6 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_7 PF13499.6 KFR04204.1 - 6.9e-05 23.2 0.1 9.5e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFR04204.1 - 0.00023 20.5 0.3 0.022 14.3 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFR04204.1 - 0.023 14.6 0.0 8.7 6.6 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain EF-hand_4 PF12763.7 KFR04204.1 - 0.12 12.4 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand S_100 PF01023.19 KFR04205.1 - 8.6e-20 70.2 1.3 1.1e-19 69.9 0.3 1.6 2 0 0 2 2 2 1 S-100/ICaBP type calcium binding domain EF-hand_7 PF13499.6 KFR04205.1 - 0.00039 20.8 0.7 0.00061 20.2 0.7 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_4 PF12763.7 KFR04205.1 - 0.018 14.9 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand EF-hand_6 PF13405.6 KFR04205.1 - 0.04 13.9 5.2 1 9.5 0.3 3.0 1 1 2 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 KFR04205.1 - 0.23 11.1 6.0 0.31 10.7 0.5 3.0 3 1 1 4 4 4 0 EF hand S_100 PF01023.19 KFR04206.1 - 2.5e-11 43.1 0.0 3.6e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_5 PF13202.6 KFR04206.1 - 1.8e-05 24.0 0.5 0.00025 20.4 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 KFR04206.1 - 2.6e-05 23.4 0.3 0.0014 18.1 0.2 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KFR04206.1 - 2.8e-05 24.5 0.1 9.1e-05 22.8 0.1 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KFR04206.1 - 0.0024 17.7 0.7 0.0064 16.3 0.3 1.8 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KFR04206.1 - 0.0063 16.4 0.1 1 9.5 0.0 2.6 2 1 0 2 2 2 1 EF-hand domain UL11 PF11094.8 KFR04206.1 - 4.7 7.2 5.9 3.9 7.4 3.3 2.0 2 0 0 2 2 2 0 Membrane-associated tegument protein S_100 PF01023.19 KFR04207.1 - 1.7e-09 37.2 0.0 2.5e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain S_100 PF01023.19 KFR04208.1 - 5.6e-16 58.0 0.2 9.1e-16 57.3 0.2 1.4 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.32 KFR04208.1 - 0.027 14.0 0.5 9.5 6.0 0.1 2.9 3 0 0 3 3 3 0 EF hand TPR_15 PF13429.6 KFR04208.1 - 0.049 12.8 0.0 0.057 12.6 0.0 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat S_100 PF01023.19 KFR04209.1 - 3.5e-22 77.8 1.5 5.1e-22 77.3 1.5 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.32 KFR04209.1 - 1.3e-07 30.6 0.5 4.2e-06 25.9 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KFR04209.1 - 1.4e-06 28.6 0.2 1.9e-06 28.2 0.2 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KFR04209.1 - 8.9e-05 21.8 2.5 0.0016 17.8 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KFR04209.1 - 0.00019 21.1 0.1 0.25 11.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KFR04209.1 - 0.016 15.1 0.9 0.052 13.4 0.7 1.9 1 1 1 2 2 2 0 EF-hand domain pair Sigma54_CBD PF04963.13 KFR04209.1 - 0.054 13.3 0.1 0.067 13.0 0.1 1.1 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain EF-hand_4 PF12763.7 KFR04209.1 - 0.06 13.3 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand DEK_C PF08766.11 KFR04209.1 - 0.11 12.5 0.4 0.18 11.8 0.4 1.5 1 1 0 1 1 1 0 DEK C terminal domain FoP_duplication PF13865.6 KFR04210.1 - 4.8e-22 78.3 6.8 4.8e-22 78.3 6.8 2.8 1 1 2 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Sbi-IV PF11621.8 KFR04210.1 - 0.18 12.2 10.0 5.7 7.4 0.0 4.0 2 2 2 4 4 4 0 C3 binding domain 4 of IgG-bind protein SBI Snapin_Pallidin PF14712.6 KFR04211.1 - 1.1e-17 64.1 2.8 1.4e-17 63.9 2.8 1.1 1 0 0 1 1 1 1 Snapin/Pallidin DZF PF07528.14 KFR04212.1 - 6.6e-96 320.7 0.0 8.6e-96 320.3 0.0 1.1 1 0 0 1 1 1 1 DZF domain SMODS PF18144.1 KFR04212.1 - 0.041 14.1 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain NTP_transf_2 PF01909.23 KFR04212.1 - 0.11 12.8 0.0 0.41 11.0 0.0 2.0 2 0 0 2 2 2 0 Nucleotidyltransferase domain ANF_receptor PF01094.28 KFR04213.1 - 7.4e-20 71.3 0.0 8.4e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 KFR04213.1 - 0.044 12.8 0.0 0.049 12.6 0.0 1.0 1 0 0 1 1 1 0 Periplasmic binding protein domain Guanylate_cyc PF00211.20 KFR04214.1 - 9.8e-40 136.1 0.0 4.8e-38 130.6 0.0 2.1 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KFR04214.1 - 8e-05 22.2 0.7 0.00012 21.6 0.7 1.2 1 0 0 1 1 1 1 Heme NO binding associated Pkinase_Tyr PF07714.17 KFR04214.1 - 0.00026 20.4 0.0 0.00043 19.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DIRP PF06584.13 KFR04214.1 - 0.0052 17.0 0.2 0.0089 16.2 0.2 1.3 1 0 0 1 1 1 1 DIRP CHASE6_C PF17150.4 KFR04214.1 - 0.043 14.5 0.1 0.076 13.7 0.1 1.4 1 0 0 1 1 1 0 C-terminal domain of two-partite extracellular sensor domain CARD PF00619.21 KFR04214.1 - 0.07 13.2 0.3 0.18 11.9 0.3 1.6 1 0 0 1 1 1 0 Caspase recruitment domain Ints3 PF10189.9 KFR04215.1 - 6.4e-73 244.7 0.7 6.4e-73 244.7 0.7 1.6 2 0 0 2 2 2 1 Integrator complex subunit 3 Aconitase_B_N PF11791.8 KFR04215.1 - 0.16 12.0 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Aconitate B N-terminal domain JTB PF05439.12 KFR04216.1 - 4.1e-22 78.3 3.7 4.4e-22 78.2 3.7 1.0 1 0 0 1 1 1 1 Jumping translocation breakpoint protein (JTB) L_HMGIC_fpl PF10242.9 KFR04216.1 - 0.017 15.3 0.7 0.02 15.1 0.7 1.0 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein Ras PF00071.22 KFR04217.1 - 2.7e-28 98.6 0.1 2.9e-28 98.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR04217.1 - 4.7e-15 55.9 0.0 5.5e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR04217.1 - 5.6e-06 25.9 0.1 6.2e-06 25.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFR04217.1 - 0.0076 15.8 0.0 0.0088 15.6 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Sen15 PF09631.10 KFR04217.1 - 0.14 12.5 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Sen15 protein CTD_bind PF04818.13 KFR04218.1 - 1.9e-17 63.9 2.0 2.1e-17 63.7 0.2 2.2 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CREPT PF16566.5 KFR04218.1 - 1.1e-07 32.1 0.6 1.1e-07 32.1 0.6 1.9 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour Acetyltransf_11 PF13720.6 KFR04218.1 - 0.08 13.4 0.1 11 6.5 0.0 2.6 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 FadA PF09403.10 KFR04218.1 - 0.83 10.2 5.5 10 6.7 0.3 3.4 2 1 1 3 3 3 0 Adhesion protein FadA PRP3 PF08572.10 KFR04219.1 - 2.3e-80 269.5 6.8 2.3e-80 269.5 6.8 3.1 3 1 0 3 3 3 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KFR04219.1 - 1.5e-48 164.6 1.8 1.5e-48 164.6 1.8 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1115) PWI PF01480.17 KFR04219.1 - 1.9e-13 50.5 0.0 5.4e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 PWI domain TPX2 PF06886.11 KFR04219.1 - 0.058 13.6 0.4 0.058 13.6 0.4 5.8 6 0 0 6 6 6 0 Targeting protein for Xklp2 (TPX2) UPF0767 PF15990.5 KFR04219.1 - 8 6.7 6.3 7.7 6.7 0.8 3.0 2 0 0 2 2 2 0 UPF0767 family Aph-1 PF06105.12 KFR04220.1 - 6.3e-76 254.8 9.3 7.1e-76 254.6 9.3 1.0 1 0 0 1 1 1 1 Aph-1 protein OST3_OST6 PF04756.13 KFR04220.1 - 0.022 14.1 1.3 0.022 14.1 1.3 2.4 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family LRR_4 PF12799.7 KFR04221.1 - 1.6e-16 60.1 20.7 1.2e-08 35.1 6.0 3.3 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFR04221.1 - 5.1e-16 58.7 0.5 6.5e-16 58.3 0.5 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KFR04221.1 - 6.9e-08 32.1 4.2 6.9e-08 32.1 4.2 3.1 1 1 2 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 KFR04221.1 - 1.8e-07 30.6 8.9 0.0012 18.7 0.2 4.0 3 0 0 3 3 3 3 Leucine Rich repeat LRR_1 PF00560.33 KFR04221.1 - 1.2e-05 25.2 8.5 1.9 9.3 0.1 4.5 4 0 0 4 4 4 3 Leucine Rich Repeat CobT PF06213.12 KFR04221.1 - 0.18 11.2 14.2 0.22 10.9 14.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT LRR_2 PF07723.13 KFR04221.1 - 0.29 11.9 1.4 61 4.5 0.1 3.8 4 0 0 4 4 4 0 Leucine Rich Repeat SDA1 PF05285.12 KFR04221.1 - 5.8 6.2 16.6 6.4 6.1 16.6 1.1 1 0 0 1 1 1 0 SDA1 PH PF00169.29 KFR04222.1 - 7.2e-13 49.0 0.8 1.8e-12 47.7 0.8 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KFR04222.1 - 0.00078 19.8 0.6 0.013 15.9 0.6 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFR04222.1 - 0.019 15.4 0.8 0.019 15.4 0.8 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain DTW PF03942.15 KFR04222.1 - 0.14 11.8 4.2 0.1 12.3 1.2 2.1 1 1 0 2 2 2 0 DTW domain DUF3055 PF11256.8 KFR04222.1 - 0.26 11.6 2.4 1.5 9.1 0.2 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3055) OTU PF02338.19 KFR04223.1 - 3.3e-24 85.8 0.0 6.9e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease UBA_4 PF14555.6 KFR04223.1 - 0.00013 21.7 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 KFR04223.1 - 0.00053 19.6 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 TAP C-terminal domain RPA43_OB PF17875.1 KFR04223.1 - 1 10.0 4.9 2.5 8.7 0.1 2.7 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I RRM_1 PF00076.22 KFR04224.1 - 1.2e-39 133.9 0.0 7.1e-20 70.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFR04224.1 - 3.8e-06 26.9 0.0 0.0014 18.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 KFR04224.1 - 0.00074 19.1 0.0 0.54 9.8 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 KFR04224.1 - 0.01 15.5 0.1 0.27 10.9 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain Limkain-b1 PF11608.8 KFR04224.1 - 0.053 13.6 0.0 2.9 8.0 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 RGM_N PF06535.12 KFR04225.1 - 2.1e-69 232.9 0.7 3.1e-69 232.4 0.7 1.3 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) N-terminus RGM_C PF06534.13 KFR04225.1 - 1.6e-64 216.6 0.3 3.9e-64 215.3 0.3 1.6 1 1 0 1 1 1 1 Repulsive guidance molecule (RGM) C-terminus VWD PF00094.25 KFR04225.1 - 0.031 14.6 0.0 0.05 13.9 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type D domain Transglut_C PF00927.22 KFR04264.1 - 2.1e-38 130.7 0.2 2.3e-20 72.7 0.0 2.7 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_N PF00868.20 KFR04264.1 - 2.4e-32 111.7 0.3 5.2e-32 110.7 0.3 1.6 1 0 0 1 1 1 1 Transglutaminase family Transglut_core PF01841.19 KFR04264.1 - 9.5e-16 58.2 0.1 2e-15 57.2 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily MG2 PF01835.19 KFR04264.1 - 0.0013 19.1 0.1 0.0038 17.7 0.1 1.7 1 0 0 1 1 1 1 MG2 domain HNF-1A_C PF04813.12 KFR04264.1 - 0.026 15.3 2.0 25 5.7 4.0 2.6 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus DUF2393 PF09624.10 KFR04264.1 - 0.14 12.2 1.7 0.2 11.7 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2393) Poxvirus_B22R PF04395.12 KFR04264.1 - 0.17 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus B22R protein Transglut_N PF00868.20 KFR04265.1 - 8.1e-29 100.4 0.0 2.3e-28 98.9 0.0 1.8 1 0 0 1 1 1 1 Transglutaminase family Transglut_C PF00927.22 KFR04265.1 - 2.2e-25 88.8 0.1 8.7e-13 48.3 0.0 2.6 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 KFR04265.1 - 3.2e-17 63.0 0.2 8.7e-17 61.6 0.2 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_N PF00868.20 KFR04266.1 - 1.5e-32 112.4 0.0 4e-32 111.0 0.0 1.8 1 0 0 1 1 1 1 Transglutaminase family Transglut_C PF00927.22 KFR04266.1 - 2.9e-29 101.3 0.3 2.4e-14 53.3 0.1 2.5 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 KFR04266.1 - 3.4e-16 59.7 0.2 7.6e-16 58.6 0.2 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_N PF00868.20 KFR04267.1 - 1.1e-34 119.2 0.0 2.1e-34 118.4 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase family Transglut_C PF00927.22 KFR04267.1 - 7e-28 96.9 0.0 3.3e-16 59.3 0.0 3.2 3 0 0 3 3 3 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 KFR04267.1 - 8e-18 64.9 0.9 1.5e-17 64.0 0.9 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily SUR7 PF06687.12 KFR04267.1 - 0.073 12.7 0.2 0.11 12.1 0.2 1.3 1 0 0 1 1 1 0 SUR7/PalI family MG2 PF01835.19 KFR04267.1 - 0.11 13.0 0.0 0.37 11.3 0.0 1.8 2 0 0 2 2 2 0 MG2 domain GCIP PF13324.6 KFR04268.1 - 1.7e-89 299.9 1.4 1.9e-89 299.7 1.4 1.0 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting PMEI PF04043.15 KFR04268.1 - 0.08 13.3 3.3 1.1 9.6 1.2 2.9 1 1 1 2 2 2 0 Plant invertase/pectin methylesterase inhibitor DEAD PF00270.29 KFR04269.1 - 1.3e-45 155.3 0.2 1.1e-44 152.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFR04269.1 - 7.4e-30 103.6 0.3 3e-28 98.4 0.1 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFR04269.1 - 2.1e-06 27.9 0.0 2.1e-06 27.9 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KFR04269.1 - 0.0017 18.7 1.9 0.017 15.4 1.9 2.6 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 KFR04269.1 - 0.3 10.8 0.0 0.3 10.8 0.0 3.0 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family LSM PF01423.22 KFR04270.1 - 0.017 14.8 0.0 0.023 14.4 0.0 1.1 1 0 0 1 1 1 0 LSM domain DUF3361 PF11841.8 KFR04272.1 - 1.9e-59 200.1 6.9 4.2e-59 198.9 6.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.13 KFR04272.1 - 5.9e-40 137.2 0.3 1e-39 136.5 0.3 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 KFR04272.1 - 1.9e-38 132.0 0.1 8.6e-38 129.9 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain SIL1 PF16782.5 KFR04272.1 - 0.0028 16.9 2.6 0.007 15.6 2.5 1.6 1 1 0 1 1 1 1 Nucleotide exchange factor SIL1 Cas_CT1975 PF09344.10 KFR04272.1 - 0.054 13.0 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 CT1975-like protein Cadherin PF00028.17 KFR04273.1 - 2.4e-81 268.3 12.2 3.7e-20 72.2 0.1 5.5 5 1 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFR04273.1 - 3.4e-48 163.6 0.3 6.5e-48 162.7 0.3 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.12 KFR04273.1 - 4.3e-07 29.7 0.2 0.19 11.6 0.0 4.3 4 0 0 4 4 4 2 Cadherin-like Cadherin_3 PF16184.5 KFR04273.1 - 1.6e-05 24.8 7.1 1.7 8.7 0.3 4.8 4 0 0 4 4 4 2 Cadherin-like GRP PF07172.11 KFR04273.1 - 0.014 16.1 0.1 0.028 15.1 0.1 1.4 1 0 0 1 1 1 0 Glycine rich protein family TAS2R PF05296.13 KFR04273.1 - 0.045 12.9 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 Taste receptor protein (TAS2R) Cadherin_pro PF08758.11 KFR04273.1 - 0.045 13.9 0.1 0.16 12.1 0.1 2.0 1 0 0 1 1 1 0 Cadherin prodomain like 7TM_GPCR_Srw PF10324.9 KFR04273.1 - 0.077 12.3 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Stevor PF17410.2 KFR04273.1 - 0.099 12.2 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Invasin_D3 PF09134.10 KFR04273.1 - 0.17 12.2 4.3 8.6 6.7 0.0 3.7 3 1 0 3 3 3 0 Invasin, domain 3 TNFR_c6 PF00020.18 KFR04274.1 - 4.1e-17 62.3 39.2 4.4e-07 30.2 1.8 4.7 4 0 0 4 4 4 3 TNFR/NGFR cysteine-rich region AA_permease PF00324.21 KFR04275.1 - 1.5e-52 178.8 20.3 2.3e-40 138.6 4.2 2.1 2 0 0 2 2 2 2 Amino acid permease SLC12 PF03522.15 KFR04275.1 - 2.4e-51 175.1 8.5 1.3e-18 67.3 2.4 3.2 1 1 2 3 3 3 3 Solute carrier family 12 AA_permease_2 PF13520.6 KFR04275.1 - 6.4e-16 58.2 10.2 6.4e-16 58.2 10.2 2.1 2 0 0 2 2 2 2 Amino acid permease zf-H2C2_5 PF13909.6 KFR04276.1 - 1.2e-29 101.6 87.9 3.7e-07 29.8 8.0 10.1 10 0 0 10 10 10 8 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KFR04276.1 - 1.4e-26 91.7 100.0 1.2e-06 28.7 0.2 13.8 15 0 0 15 15 15 8 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR04276.1 - 1.1e-23 81.8 109.9 0.0016 19.1 0.6 13.7 13 0 0 13 13 13 11 C2H2-type zinc finger zf-C2H2 PF00096.26 KFR04276.1 - 9.3e-22 76.2 115.8 0.0037 17.7 0.8 13.4 13 0 0 13 13 13 11 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFR04276.1 - 0.0006 19.7 0.1 0.0006 19.7 0.1 8.7 11 1 0 11 11 11 2 C2H2-type zinc finger ADK_lid PF05191.14 KFR04276.1 - 0.011 15.6 3.5 0.011 15.6 3.5 3.5 4 0 0 4 4 4 0 Adenylate kinase, active site lid zf-C2H2_2 PF12756.7 KFR04276.1 - 0.032 14.6 0.2 0.032 14.6 0.2 10.6 3 2 5 9 9 9 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KFR04276.1 - 0.056 13.8 0.0 0.056 13.8 0.0 10.2 10 1 1 11 11 11 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFR04276.1 - 0.06 13.8 0.2 0.06 13.8 0.2 10.0 9 0 0 9 9 9 0 Zinc-finger of C2H2 type Actin_micro PF17003.5 KFR04276.1 - 0.097 11.8 0.0 0.097 11.8 0.0 6.9 3 2 2 5 5 5 0 Putative actin-like family Homeobox_KN PF05920.11 KFR04277.1 - 3.2e-15 55.8 0.1 4e-15 55.4 0.1 1.1 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFR04277.1 - 8.7e-07 28.7 0.1 9.2e-07 28.6 0.1 1.1 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 KFR04277.1 - 0.019 14.5 0.1 0.031 13.7 0.1 1.5 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Phage_P2_GpE PF06528.12 KFR04277.1 - 0.077 12.6 1.3 0.084 12.4 0.1 1.7 2 0 0 2 2 2 0 Phage P2 GpE PCIF1_WW PF12237.8 KFR04278.1 - 1.9e-69 232.7 0.2 2.9e-69 232.1 0.2 1.3 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain WW PF00397.26 KFR04278.1 - 5.8e-11 42.3 0.4 1.1e-10 41.4 0.4 1.5 1 0 0 1 1 1 1 WW domain Chorion_2 PF03964.15 KFR04278.1 - 0.033 15.0 2.4 0.099 13.5 2.4 1.8 1 0 0 1 1 1 0 Chorion family 2 IMUP PF15761.5 KFR04278.1 - 1.1 10.0 11.4 2.7 8.7 11.4 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 KFR04278.1 - 3.4 7.2 21.0 0.11 12.0 14.6 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein LBP_BPI_CETP_C PF02886.17 KFR04279.1 - 1.2e-60 204.9 0.2 1.9e-60 204.3 0.2 1.3 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 KFR04279.1 - 1.1e-29 103.1 0.7 6.2e-29 100.7 0.3 2.1 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain TGBp3 PF02495.17 KFR04279.1 - 0.088 12.5 0.3 9.4 6.0 0.1 2.4 2 0 0 2 2 2 0 Triple gene block 3 SWIM PF04434.17 KFR04280.1 - 2.4e-07 30.3 0.2 4.8e-07 29.3 0.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger 4HBT_3 PF13622.6 KFR04281.1 - 4.5e-49 167.9 0.0 5.1e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KFR04281.1 - 1e-29 103.1 0.0 2.7e-27 95.2 0.0 2.1 2 0 0 2 2 2 2 Acyl-CoA thioesterase EF-hand_7 PF13499.6 KFR04283.1 - 3.6e-30 104.2 9.7 7.9e-17 61.5 4.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFR04283.1 - 2.3e-29 98.7 23.2 2.3e-08 33.0 0.7 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KFR04283.1 - 1e-23 81.2 15.1 8.3e-07 28.5 0.1 4.7 3 1 2 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 KFR04283.1 - 2.1e-23 81.9 17.2 2.8e-13 49.5 0.6 3.5 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KFR04283.1 - 3.1e-20 70.7 20.7 6.1e-06 25.5 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KFR04283.1 - 2e-17 63.2 0.7 2.7e-08 34.0 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KFR04283.1 - 5.3e-07 30.0 0.7 0.00039 20.7 0.4 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFR04283.1 - 5.2e-06 26.4 9.4 0.026 14.5 0.6 3.5 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand TerB PF05099.13 KFR04283.1 - 0.0019 18.1 2.2 0.11 12.5 0.4 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB p25-alpha PF05517.12 KFR04283.1 - 0.0025 18.0 0.7 0.084 13.0 0.1 2.2 1 1 0 2 2 2 1 p25-alpha EF-hand_11 PF08976.11 KFR04283.1 - 0.004 18.0 0.1 4.2 8.3 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain DUF1456 PF07308.13 KFR04283.1 - 0.018 15.4 3.1 1.2 9.5 0.2 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1456) DUF5580 PF17743.1 KFR04283.1 - 0.032 12.8 0.0 0.039 12.5 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) FlgD PF03963.14 KFR04283.1 - 0.061 13.6 0.1 3.7 7.9 0.0 2.4 2 0 0 2 2 2 0 Flagellar hook capping protein - N-terminal region SapB_1 PF05184.15 KFR04283.1 - 0.083 12.9 0.1 3 8.0 0.0 2.5 2 0 0 2 2 2 0 Saposin-like type B, region 1 Phage_TAC_12 PF12363.8 KFR04283.1 - 0.086 13.3 0.8 8.4 6.9 0.1 2.2 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC HopW1-1 PF15457.6 KFR04283.1 - 0.17 11.1 0.1 5 6.3 0.0 2.0 1 1 1 2 2 2 0 Type III T3SS secreted effector HopW1-1/HopPmaA PTS_2-RNA PF01885.16 KFR04283.1 - 0.17 11.9 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF1707 PF08044.11 KFR04283.1 - 0.19 11.8 1.2 36 4.5 0.1 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1707) VbhA PF18495.1 KFR04283.1 - 0.22 11.4 3.2 16 5.5 0.1 4.1 4 1 0 4 4 4 0 Antitoxin VbhA DNTTIP1_dimer PF18192.1 KFR04284.1 - 9.9e-28 96.3 0.1 1.4e-27 95.8 0.1 1.2 1 0 0 1 1 1 1 DNTTIP1 dimerisation domain DUF4385 PF14328.6 KFR04284.1 - 0.11 12.6 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4385) LolA PF03548.15 KFR04284.1 - 0.11 12.2 0.0 2.6 7.7 0.0 2.4 2 1 0 2 2 2 0 Outer membrane lipoprotein carrier protein LolA WAP PF00095.21 KFR04285.1 - 5e-24 84.4 59.4 3e-10 40.3 16.0 3.1 3 0 0 3 3 3 3 WAP-type (Whey Acidic Protein) 'four-disulfide core' WAP PF00095.21 KFR04286.1 - 1.3e-09 38.2 23.5 3.4e-09 36.9 16.6 2.1 2 0 0 2 2 2 2 WAP-type (Whey Acidic Protein) 'four-disulfide core' CTNNBL PF08216.11 KFR04287.1 - 7.9e-40 135.2 1.9 3.1e-39 133.3 1.9 2.1 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.23 KFR04287.1 - 0.0019 18.1 5.1 3 8.0 0.2 3.9 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 KFR04287.1 - 0.042 13.9 0.1 0.2 11.7 0.1 2.2 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain RecO_C PF02565.15 KFR04287.1 - 0.048 13.5 1.1 40 4.0 0.1 3.5 2 1 0 3 3 3 0 Recombination protein O C terminal DASH_Dad4 PF08650.10 KFR04287.1 - 0.079 12.9 0.8 11 6.1 0.1 3.7 3 0 0 3 3 3 0 DASH complex subunit Dad4 Lipase_GDSL PF00657.22 KFR04287.1 - 0.14 12.1 0.0 0.54 10.2 0.0 2.0 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase DUF262 PF03235.14 KFR04287.1 - 5.6 7.1 7.0 14 5.8 2.6 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF262 V-set PF07686.17 KFR04288.1 - 2e-11 44.0 0.2 2.9e-11 43.5 0.2 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFR04288.1 - 1.4e-09 37.9 0.4 1.9e-08 34.2 0.4 2.2 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR04288.1 - 5.1e-08 33.4 0.3 1.4e-07 32.0 0.3 1.7 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFR04288.1 - 1.1e-06 28.6 0.2 2.4e-06 27.6 0.2 1.5 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFR04288.1 - 0.0021 18.4 0.1 0.048 14.0 0.1 2.2 1 1 0 1 1 1 1 Immunoglobulin domain VHS PF00790.19 KFR04289.1 - 0.0006 19.7 2.4 0.23 11.3 0.0 4.4 3 1 0 3 3 3 1 VHS domain Cnd1 PF12717.7 KFR04289.1 - 0.019 15.0 0.8 0.18 11.9 0.0 3.0 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 DUF5331 PF17265.2 KFR04289.1 - 0.031 14.0 0.0 0.082 12.6 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5331) DUF5503 PF17607.2 KFR04289.1 - 0.041 14.2 0.0 0.088 13.1 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5503) Vac14_Fab1_bd PF12755.7 KFR04289.1 - 0.041 14.5 0.2 5.5 7.7 0.0 3.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KFR04289.1 - 0.047 14.0 17.5 25 5.5 0.0 7.9 8 0 0 8 8 8 0 HEAT repeat Dopey_N PF04118.14 KFR04289.1 - 0.054 12.6 0.1 0.054 12.6 0.1 3.5 3 2 1 4 4 4 0 Dopey, N-terminal Adaptin_N PF01602.20 KFR04289.1 - 0.067 11.7 3.8 3.7 6.0 0.0 3.3 3 0 0 3 3 3 0 Adaptin N terminal region CREPT PF16566.5 KFR04290.1 - 6.9e-63 211.2 5.5 6.9e-63 211.2 5.5 1.7 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour CTD_bind PF04818.13 KFR04290.1 - 2.3e-22 79.6 3.1 7.3e-22 78.0 0.0 3.1 3 1 0 3 3 3 1 RNA polymerase II-binding domain. Rep_4 PF05797.11 KFR04290.1 - 0.088 11.9 4.0 0.19 10.8 1.9 2.1 2 0 0 2 2 2 0 Yeast trans-acting factor (REP1/REP2) DUF2294 PF10057.9 KFR04290.1 - 0.098 12.8 1.7 0.42 10.8 0.4 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) DUF2408 PF10303.9 KFR04290.1 - 2.4 8.8 9.3 2.2 8.9 1.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Swi5 PF07061.11 KFR04290.1 - 2.5 8.3 12.4 4 7.6 2.1 3.4 3 1 0 3 3 3 0 Swi5 Takusan PF04822.13 KFR04290.1 - 3 7.8 12.0 2.9 7.8 2.1 2.9 2 0 0 2 2 2 0 Takusan Dzip-like_N PF13815.6 KFR04290.1 - 4.4 7.3 8.7 0.5 10.3 2.6 2.3 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal FemAB PF02388.16 KFR04290.1 - 4.5 6.0 7.6 0.2 10.5 1.6 1.6 2 0 0 2 2 2 0 FemAB family Transglut_C PF00927.22 KFR04291.1 - 7.3e-44 148.3 0.0 1.3e-21 76.7 0.0 2.6 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_N PF00868.20 KFR04291.1 - 2.8e-35 121.2 0.0 4.8e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase family Transglut_core PF01841.19 KFR04291.1 - 9.2e-18 64.7 0.6 1.8e-17 63.8 0.6 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily LBP_BPI_CETP_C PF02886.17 KFR04294.1 - 1.4e-71 240.8 0.3 2.3e-71 240.1 0.3 1.4 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 KFR04294.1 - 2e-38 131.6 0.1 8e-38 129.6 0.0 2.1 2 1 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain JHBP PF06585.11 KFR04294.1 - 0.04 13.1 0.1 0.078 12.1 0.1 1.4 1 0 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) Radical_SAM PF04055.21 KFR04295.1 - 3.3e-30 105.6 0.0 6.4e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 KFR04295.1 - 4e-30 103.8 0.1 8.6e-30 102.7 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 KFR04295.1 - 2.4e-13 49.8 0.0 4.9e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 TRAM domain LBP_BPI_CETP_C PF02886.17 KFR04296.1 - 5.9e-27 94.6 0.4 2.2e-26 92.8 0.1 2.0 2 0 0 2 2 2 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 KFR04296.1 - 1.2e-20 73.8 0.4 3.7e-20 72.2 0.1 1.9 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP_C PF02886.17 KFR04297.1 - 1.6e-18 67.1 0.3 2.3e-18 66.5 0.3 1.1 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 KFR04298.1 - 1.9e-15 56.8 0.1 3.6e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP_C PF02886.17 KFR04298.1 - 8.3e-13 48.3 0.3 6.1e-12 45.5 0.1 2.1 2 0 0 2 2 2 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 KFR04299.1 - 2.6e-08 33.7 0.3 3.4e-07 30.0 0.0 2.5 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP_C PF02886.17 KFR04299.1 - 2.2e-07 30.6 2.1 4.1e-07 29.7 1.4 1.8 1 1 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 KFR04300.1 - 2.6e-22 79.2 7.7 2.6e-22 79.2 7.7 2.1 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP_C PF02886.17 KFR04300.1 - 6.6e-13 48.7 0.5 6.6e-13 48.7 0.5 2.0 2 1 0 2 2 2 1 LBP / BPI / CETP family, C-terminal domain EB1 PF03271.17 KFR04301.1 - 3.4e-18 65.6 0.8 1.9e-17 63.2 0.7 2.1 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.31 KFR04301.1 - 6.9e-14 51.9 0.8 1e-13 51.4 0.2 1.6 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFR04301.1 - 0.012 15.4 0.1 0.038 13.8 0.0 1.8 2 1 1 3 3 3 0 CAMSAP CH domain SUIM_assoc PF16619.5 KFR04301.1 - 0.098 12.7 0.3 0.24 11.5 0.0 1.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CCDC106 PF15794.5 KFR04301.1 - 0.22 11.2 0.1 0.35 10.5 0.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 ADD_DNMT3 PF17980.1 KFR04302.1 - 2.3e-27 94.8 0.5 5.4e-27 93.6 0.5 1.7 1 0 0 1 1 1 1 Cysteine rich ADD domain in DNMT3 PWWP PF00855.17 KFR04302.1 - 7.8e-12 45.4 0.1 1.9e-11 44.2 0.1 1.6 1 0 0 1 1 1 1 PWWP domain DNA_methylase PF00145.17 KFR04302.1 - 1.4e-09 37.8 0.0 1.5e-06 27.8 0.0 3.2 3 0 0 3 3 3 2 C-5 cytosine-specific DNA methylase RBB1NT PF08169.11 KFR04302.1 - 0.18 12.0 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 RBB1NT (NUC162) domain COMM_domain PF07258.14 KFR04303.1 - 1.8e-17 63.2 0.1 4.1e-17 62.1 0.1 1.7 1 0 0 1 1 1 1 COMM domain Integrase_H2C2 PF17921.1 KFR04304.1 - 0.00013 22.0 0.0 0.00025 21.1 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFR04304.1 - 0.12 12.7 0.3 0.27 11.5 0.3 1.7 1 1 0 1 1 1 0 H2C2 zinc finger ASXH PF13919.6 KFR04305.1 - 1e-36 126.0 0.1 2.3e-36 124.9 0.1 1.6 1 0 0 1 1 1 1 Asx homology domain HARE-HTH PF05066.13 KFR04305.1 - 5.7e-15 55.5 0.0 1.5e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain Kinesin PF00225.23 KFR04306.1 - 1.4e-122 408.8 1.0 1.4e-122 408.8 1.0 2.2 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KFR04306.1 - 9.9e-29 100.2 0.0 9.9e-29 100.2 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding AAA_16 PF13191.6 KFR04306.1 - 0.098 13.0 0.0 0.098 13.0 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain DUF948 PF06103.11 KFR04306.1 - 7.9 6.8 11.0 0.66 10.3 3.7 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) O-FucT PF10250.9 KFR04307.1 - 9.3e-62 209.7 0.0 1.1e-61 209.4 0.0 1.0 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase zf-H2C2_2 PF13465.6 KFR04308.1 - 2.4e-21 75.1 47.1 5.9e-05 23.3 4.7 7.5 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR04308.1 - 2.7e-21 74.4 56.0 0.00064 20.3 1.4 7.6 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2 PF00096.26 KFR04308.1 - 1.7e-17 62.8 61.5 7.4e-05 23.0 1.8 7.5 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFR04308.1 - 5.8e-06 26.2 44.2 0.00046 20.1 0.8 6.9 7 0 0 7 7 7 3 C2H2-type zinc finger zf-Di19 PF05605.12 KFR04308.1 - 0.00099 19.4 30.2 0.025 14.9 6.5 4.4 1 1 4 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 KFR04308.1 - 0.0063 16.2 2.0 0.13 12.0 0.3 5.8 6 0 0 6 6 6 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFR04308.1 - 0.0071 16.6 29.4 0.42 11.0 2.9 6.3 5 1 1 6 6 6 2 Zinc-finger double-stranded RNA-binding Acyltransf_C PF16076.5 KFR04308.1 - 0.016 15.3 0.8 7.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Acyltransferase C-terminus zf-met2 PF12907.7 KFR04308.1 - 0.087 13.0 0.4 0.087 13.0 0.4 3.1 3 1 1 4 4 4 0 Zinc-binding Equine_IAV_S2 PF06502.11 KFR04308.1 - 0.16 12.1 0.3 0.47 10.6 0.3 1.8 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein HNH_5 PF14279.6 KFR04308.1 - 0.19 11.6 12.4 2.5 8.0 0.4 4.3 3 1 0 3 3 3 0 HNH endonuclease zf-met PF12874.7 KFR04308.1 - 0.26 11.7 21.9 1 9.9 0.2 5.1 5 0 0 5 5 4 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFR04308.1 - 0.44 10.9 38.3 1 9.7 1.0 6.2 1 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) TF_Zn_Ribbon PF08271.12 KFR04308.1 - 1.3 8.6 4.9 3.9 7.1 0.4 2.9 2 1 0 2 2 2 0 TFIIB zinc-binding FYDLN_acid PF09538.10 KFR04308.1 - 3.2 8.5 11.8 13 6.5 0.0 4.3 2 2 2 4 4 4 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_15 PF17032.5 KFR04308.1 - 6.1 7.7 17.4 1.3 9.8 2.1 3.7 2 1 0 3 3 3 0 zinc-ribbon family EMP70 PF02990.16 KFR04309.1 - 5e-204 678.8 12.8 6.8e-204 678.3 12.8 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Pkinase_Tyr PF07714.17 KFR04310.1 - 1.3e-94 316.3 0.0 1.7e-94 316.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR04310.1 - 1.9e-47 161.9 0.0 2.3e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFR04310.1 - 7e-24 83.7 0.0 1.4e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFR04310.1 - 3.3e-16 58.6 0.0 7e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFR04310.1 - 2.9e-12 46.3 0.0 6.2e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFR04310.1 - 1.2e-09 37.7 0.0 2.6e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFR04310.1 - 0.0036 17.5 0.1 0.0077 16.5 0.1 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain Haspin_kinase PF12330.8 KFR04310.1 - 0.005 15.8 0.2 0.014 14.3 0.2 1.7 1 1 0 1 1 1 1 Haspin like kinase domain CCM2_C PF16545.5 KFR04311.1 - 2e-49 166.2 0.1 3.8e-49 165.3 0.1 1.5 1 0 0 1 1 1 1 Cerebral cavernous malformation protein, harmonin-homology DUF1722 PF08349.11 KFR04311.1 - 0.031 14.5 0.0 0.093 13.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) XK-related PF09815.9 KFR04312.1 - 1.7e-102 343.0 24.1 2e-102 342.8 24.1 1.0 1 0 0 1 1 1 1 XK-related protein ECF_trnsprt PF12822.7 KFR04312.1 - 0.22 11.6 11.9 0.43 10.7 11.9 1.5 1 0 0 1 1 1 0 ECF transporter, substrate-specific component DSPc PF00782.20 KFR04313.1 - 3.6e-32 111.0 0.0 5.6e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFR04313.1 - 1.2e-06 28.8 0.0 1.7e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KFR04313.1 - 1.5e-06 28.0 0.0 1.8e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase IRF-3 PF10401.9 KFR04314.1 - 2.5e-53 180.5 0.0 3.3e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.17 KFR04314.1 - 6.1e-29 100.4 0.8 9.5e-29 99.8 0.8 1.3 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor Pkinase PF00069.25 KFR04315.1 - 3.2e-21 75.9 0.0 3.7e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR04315.1 - 3.6e-05 23.2 0.0 4.3e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase TPX2_importin PF12214.8 KFR04316.1 - 7.6e-48 162.9 69.4 1.4e-38 132.7 11.8 7.8 5 3 2 7 7 7 4 Cell cycle regulated microtubule associated protein Aurora-A_bind PF09041.10 KFR04316.1 - 6e-23 80.7 1.7 2.4e-22 78.8 1.7 2.1 1 0 0 1 1 1 1 Aurora-A binding TPX2 PF06886.11 KFR04316.1 - 4.8e-14 52.3 18.0 4.8e-14 52.3 18.0 7.5 8 1 0 8 8 8 1 Targeting protein for Xklp2 (TPX2) Bcl-2 PF00452.19 KFR04317.1 - 7.6e-32 109.9 0.0 1.3e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family BH4 PF02180.17 KFR04317.1 - 4.5e-12 45.5 0.2 7.5e-12 44.8 0.2 1.4 1 0 0 1 1 1 1 Bcl-2 homology region 4 Bcl-2_3 PF15286.6 KFR04317.1 - 0.012 16.3 0.0 0.016 15.9 0.0 1.3 1 0 0 1 1 1 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like Phe_hydrox_dim PF07976.12 KFR04317.1 - 0.15 12.1 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Phenol hydroxylase, C-terminal dimerisation domain zf-MYND PF01753.18 KFR04320.1 - 5.9e-05 23.1 14.0 0.00012 22.1 14.0 1.6 1 0 0 1 1 1 1 MYND finger MAM PF00629.23 KFR04321.1 - 5.1e-166 546.6 0.0 4.1e-35 121.1 0.0 6.1 6 0 0 6 6 6 6 MAM domain, meprin/A5/mu Ldl_recept_a PF00057.18 KFR04321.1 - 3.8e-14 52.6 48.1 1e-07 32.0 7.5 3.8 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A MLANA PF14991.6 KFR04321.1 - 0.18 12.1 0.0 0.34 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein melan-A HTH_3 PF01381.22 KFR04322.1 - 8.3e-13 48.2 0.2 1.2e-12 47.7 0.2 1.2 1 0 0 1 1 1 1 Helix-turn-helix MBF1 PF08523.10 KFR04322.1 - 1.7e-06 28.4 0.4 1.7e-06 28.4 0.4 1.9 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_31 PF13560.6 KFR04322.1 - 0.00014 22.1 0.0 0.00019 21.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KFR04322.1 - 0.021 14.8 0.2 0.029 14.4 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 KFR04322.1 - 0.043 13.6 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain WD40 PF00400.32 KFR04323.1 - 1.3e-06 29.0 0.6 1.3e-06 29.0 0.6 2.7 3 0 0 3 3 3 1 WD domain, G-beta repeat Lipocalin PF00061.23 KFR04324.1 - 5.7e-14 52.5 0.0 1e-13 51.7 0.0 1.4 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.23 KFR04325.1 - 2.5e-29 102.3 0.0 2.9e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.23 KFR04326.1 - 3.2e-05 24.1 0.0 3.2e-05 24.1 0.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF4926 PF16277.5 KFR04326.1 - 0.057 12.8 0.0 0.73 9.2 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4926) 7tm_4 PF13853.6 KFR04327.1 - 6.1e-49 167.2 14.3 7.2e-49 167.0 14.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFR04327.1 - 1.7e-26 93.1 14.8 4.4e-26 91.8 14.8 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFR04327.1 - 0.00047 19.9 7.8 0.00047 19.9 7.8 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Pou PF00157.17 KFR04328.1 - 8.7e-37 124.9 1.5 1.4e-36 124.3 0.3 1.8 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KFR04328.1 - 3.1e-19 68.5 0.6 2.7e-18 65.6 0.3 2.3 2 0 0 2 2 2 1 Homeodomain DUF2497 PF10691.9 KFR04328.1 - 0.046 14.2 0.2 16 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) Homeobox_KN PF05920.11 KFR04328.1 - 0.074 13.0 0.5 0.19 11.7 0.1 1.9 2 0 0 2 2 2 0 Homeobox KN domain HTH_31 PF13560.6 KFR04328.1 - 0.17 12.3 0.2 5.6 7.4 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain Glyco_transf_10 PF00852.19 KFR04329.1 - 1.5e-58 197.4 1.4 2e-58 197.0 1.4 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 KFR04329.1 - 1.3e-32 112.5 0.0 2.6e-32 111.6 0.0 1.5 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal mIF3 PF14877.6 KFR04329.1 - 0.047 13.4 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial translation initiation factor ABC2_membrane_3 PF12698.7 KFR04330.1 - 9e-61 205.9 43.0 1.7e-43 149.1 12.1 3.5 4 0 0 4 4 4 2 ABC-2 family transporter protein ABC_tran PF00005.27 KFR04330.1 - 9.4e-58 194.6 0.0 1.6e-29 103.2 0.0 2.8 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 KFR04330.1 - 6.3e-19 68.9 0.4 1.3e-06 28.4 0.0 4.5 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 KFR04330.1 - 0.00026 21.7 0.5 0.61 10.8 0.1 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4162) AAA_15 PF13175.6 KFR04330.1 - 0.00061 19.6 0.0 1.3 8.7 0.0 2.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 KFR04330.1 - 0.0018 18.8 0.9 0.47 10.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KFR04330.1 - 0.035 13.7 3.1 1.9 8.1 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC2_membrane_2 PF12679.7 KFR04330.1 - 0.091 12.0 8.8 0.3 10.3 8.8 1.9 1 0 0 1 1 1 0 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KFR04330.1 - 0.16 11.9 0.3 2.2 8.2 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase SbcCD_C PF13558.6 KFR04330.1 - 0.18 12.1 0.0 27 5.1 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KFR04330.1 - 0.41 10.4 1.7 5.6 6.8 0.1 2.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain GST_C_2 PF13410.6 KFR04331.1 - 5.3e-08 32.8 0.0 6.4e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFR04331.1 - 0.0012 19.1 0.0 0.0017 18.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GDA1_CD39 PF01150.17 KFR04332.1 - 1.1e-100 337.3 0.0 1.4e-100 337.0 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family UDPGP PF01704.18 KFR04333.1 - 1.1e-68 231.8 0.0 1.5e-68 231.4 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 KFR04333.1 - 0.00055 20.3 0.0 0.0013 19.1 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain Glyco_hydro_47 PF01532.20 KFR04334.1 - 5.2e-169 563.0 0.0 6.1e-169 562.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Peptidase_S28 PF05577.12 KFR04335.1 - 3.9e-83 279.7 0.0 4.7e-83 279.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 KFR04335.1 - 2e-06 27.3 0.0 2.9e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFR04335.1 - 7.5e-05 23.4 0.1 0.0037 17.9 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFR04335.1 - 0.0016 18.1 0.1 0.005 16.5 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S37 PF05576.11 KFR04335.1 - 0.0044 15.7 0.0 0.0076 15.0 0.0 1.3 1 0 0 1 1 1 1 PS-10 peptidase S37 DUF2920 PF11144.8 KFR04335.1 - 0.0063 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Peptidase_S9 PF00326.21 KFR04335.1 - 0.019 14.4 0.1 0.035 13.6 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KFR04335.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Fibrinogen_C PF00147.18 KFR04336.1 - 1.5e-40 139.3 1.7 1.7e-40 139.2 1.7 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain MORN PF02493.20 KFR04337.1 - 2.2e-10 39.8 9.0 8.8e-07 28.5 1.8 3.5 3 0 0 3 3 3 3 MORN repeat Cohesin_HEAT PF12765.7 KFR04338.1 - 0.0007 19.8 0.2 0.0025 18.1 0.2 2.0 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion FAP206 PF12018.8 KFR04338.1 - 0.013 15.0 0.1 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function HEAT_2 PF13646.6 KFR04338.1 - 0.026 14.9 2.6 0.085 13.3 1.3 2.4 2 1 0 2 2 2 0 HEAT repeats HEAT PF02985.22 KFR04338.1 - 0.031 14.5 4.7 0.12 12.6 0.1 3.8 3 0 0 3 3 3 0 HEAT repeat BAH PF01426.18 KFR04350.1 - 2.7e-43 146.7 0.0 7.3e-22 77.5 0.0 2.5 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.8 KFR04350.1 - 3.2e-28 98.6 0.2 1.1e-27 96.8 0.0 2.0 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain zf-CXXC PF02008.20 KFR04350.1 - 2.8e-15 56.0 21.2 7.8e-15 54.6 21.2 1.8 1 0 0 1 1 1 1 CXXC zinc finger domain DUF2284 PF10050.9 KFR04350.1 - 0.0012 18.6 2.7 1 9.1 0.0 2.4 2 0 0 2 2 2 2 Predicted metal-binding protein (DUF2284) DNA_methylase PF00145.17 KFR04351.1 - 7e-33 114.4 0.0 9.5e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase eIF3g PF12353.8 KFR04352.1 - 2.6e-42 144.2 2.0 4e-42 143.5 2.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KFR04352.1 - 1.1e-18 66.8 0.0 2.8e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDV3 PF15359.6 KFR04352.1 - 0.0003 21.3 1.6 0.002 18.6 1.6 2.0 1 1 0 1 1 1 1 Carnitine deficiency-associated protein 3 RRM_occluded PF16842.5 KFR04352.1 - 0.038 13.8 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif RNA_bind PF08675.11 KFR04352.1 - 0.055 13.5 0.0 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 RNA binding domain adh_short PF00106.25 KFR04353.1 - 9.2e-46 155.8 0.1 1.1e-45 155.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFR04353.1 - 7.2e-32 110.8 0.0 1e-31 110.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFR04353.1 - 2.8e-10 40.4 0.1 3.6e-10 40.0 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFR04353.1 - 0.00011 21.8 0.0 0.0005 19.6 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 KFR04353.1 - 0.0027 17.4 0.0 0.005 16.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.10 KFR04353.1 - 0.0031 16.9 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KFR04353.1 - 0.04 13.8 0.3 0.094 12.6 0.2 1.6 2 0 0 2 2 2 0 NAD(P)H-binding Atg8 PF02991.16 KFR04354.1 - 1.2e-33 115.3 0.1 1.4e-33 115.2 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KFR04354.1 - 6.1e-06 26.5 0.0 7.1e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Rotamase PF00639.21 KFR04355.1 - 9.3e-22 77.8 0.0 1.2e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KFR04355.1 - 1.6e-20 73.8 0.0 2.2e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KFR04355.1 - 3.9e-15 55.6 0.4 6.1e-15 55.0 0.1 1.5 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 KFR04355.1 - 0.0011 19.7 0.0 0.0015 19.3 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain X8 PF07983.13 KFR04355.1 - 0.0057 17.3 0.0 0.015 16.0 0.0 1.7 2 0 0 2 2 2 1 X8 domain LRIF1 PF15741.5 KFR04355.1 - 0.093 11.3 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 CX9C PF16860.5 KFR04356.1 - 3.9e-21 74.8 7.1 5.6e-16 58.3 0.1 2.1 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KFR04356.1 - 4.4e-06 26.6 9.1 0.033 14.2 0.5 3.0 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 KFR04356.1 - 6e-05 23.1 9.8 0.00022 21.2 2.6 2.4 2 1 0 2 2 2 2 CHCH domain NDUF_B7 PF05676.13 KFR04356.1 - 0.00017 21.2 0.7 0.00017 21.2 0.7 2.2 1 1 1 2 2 2 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) GCK PF07802.11 KFR04356.1 - 0.013 15.8 5.9 0.11 13.0 0.8 2.2 1 1 1 2 2 2 0 GCK domain DUF1690 PF07956.11 KFR04356.1 - 0.052 14.0 0.9 0.063 13.7 0.8 1.2 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) COX17 PF05051.13 KFR04356.1 - 0.11 12.9 4.9 4.1 7.8 2.0 3.0 2 1 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 KFR04356.1 - 0.12 12.7 8.6 1.1 9.6 6.2 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.12 KFR04356.1 - 0.13 12.5 5.7 1.1 9.5 1.1 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) E1-E2_ATPase PF00122.20 KFR04357.1 - 3.6e-21 75.5 0.0 9e-21 74.2 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KFR04357.1 - 1.2e-16 61.6 0.0 1.4e-09 38.6 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFR04357.1 - 6e-05 23.0 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFR04357.1 - 0.0062 16.3 0.0 0.28 10.9 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2464 PF10240.9 KFR04358.1 - 9.7e-35 120.4 0.0 1.1e-34 120.2 0.0 1.0 1 0 0 1 1 1 1 Multivesicular body subunit 12 End_N_terminal PF12218.8 KFR04358.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase AdoHcyase PF05221.17 KFR04360.1 - 8e-30 104.0 0.3 4.9e-20 71.9 0.1 2.1 2 0 0 2 2 2 2 S-adenosyl-L-homocysteine hydrolase TP2 PF01254.18 KFR04360.1 - 0.024 15.3 2.8 0.032 14.8 2.8 1.2 1 0 0 1 1 1 0 Nuclear transition protein 2 SR-25 PF10500.9 KFR04360.1 - 0.13 11.8 6.8 0.17 11.5 6.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF515 PF04415.12 KFR04360.1 - 3.2 6.0 6.7 4.3 5.6 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF3402 PF11882.8 KFR04361.1 - 1.5e-103 347.4 13.8 1.2e-65 222.4 5.5 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.13 KFR04361.1 - 2.4e-28 99.2 0.0 4.8e-27 94.9 0.0 2.3 2 0 0 2 2 2 1 N1221-like protein ELM2 PF01448.24 KFR04361.1 - 0.12 13.1 1.6 0.21 12.4 0.4 2.1 2 0 0 2 2 2 0 ELM2 domain Homeodomain PF00046.29 KFR04362.1 - 4.4e-25 87.3 6.4 5e-25 87.1 6.4 1.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFR04362.1 - 8.1e-05 22.4 0.2 0.00015 21.6 0.2 1.4 1 0 0 1 1 1 1 Homeobox KN domain SNF PF00209.18 KFR04363.1 - 4.8e-221 735.0 32.5 6e-221 734.7 32.5 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Tmemb_18A PF09771.9 KFR04363.1 - 5.4 7.4 7.7 0.6 10.5 0.1 3.0 4 0 0 4 4 4 0 Transmembrane protein 188 Ion_trans PF00520.31 KFR04364.1 - 4.2e-43 147.3 15.7 5.3e-43 147.0 15.7 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFR04364.1 - 1.4e-28 99.0 0.0 3.1e-28 98.0 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFR04364.1 - 1.2e-10 41.2 3.9 1.2e-10 41.2 3.9 2.5 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.5 KFR04364.1 - 0.00088 19.3 0.0 0.0033 17.5 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain DUF202 PF02656.15 KFR04364.1 - 1.8 9.1 7.9 53 4.4 4.0 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF202) SPOC PF07744.13 KFR04365.1 - 1.4e-38 132.1 0.0 2.2e-38 131.5 0.0 1.3 1 0 0 1 1 1 1 SPOC domain RRM_1 PF00076.22 KFR04365.1 - 8.2e-20 70.4 0.0 1.5e-12 47.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFR04365.1 - 7.7e-07 29.0 0.0 0.00064 19.7 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KFR04365.1 - 0.00049 20.1 0.0 0.0053 16.8 0.0 2.3 1 1 1 2 2 2 1 RNA binding motif RRM_7 PF16367.5 KFR04365.1 - 0.036 14.2 0.0 3.6 7.8 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif MFS_1 PF07690.16 KFR04366.1 - 1.8e-33 115.9 36.2 2.6e-17 62.8 15.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2929 PF11151.8 KFR04366.1 - 1 9.7 4.8 30 5.0 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2929) LAMTOR5 PF16672.5 KFR04367.1 - 4.8e-18 64.9 0.1 5.2e-18 64.8 0.1 1.0 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 Prokineticin PF06607.11 KFR04368.1 - 1.1e-38 131.5 8.7 1.2e-38 131.3 8.7 1.0 1 0 0 1 1 1 1 Prokineticin MIT_LIKE_ACTX PF17556.2 KFR04368.1 - 1.4 9.6 10.0 2.1 9.0 10.0 1.4 1 1 0 1 1 1 0 MIT-like atracotoxin family Asp PF00026.23 KFR04369.1 - 7.2e-121 403.4 7.5 8.1e-121 403.3 7.5 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFR04369.1 - 1.1e-17 64.9 5.2 3.9e-15 56.5 3.5 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Ion_trans PF00520.31 KFR04370.1 - 2.8e-50 170.9 13.4 3.5e-50 170.5 13.4 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFR04370.1 - 9.9e-24 83.5 0.1 2.4e-23 82.3 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFR04370.1 - 2.1e-13 50.0 5.8 2.1e-13 50.0 5.8 2.9 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.12 KFR04370.1 - 0.00046 19.0 0.5 0.00046 19.0 0.5 2.4 1 1 2 3 3 3 1 Polycystin cation channel DUF423 PF04241.15 KFR04370.1 - 0.49 10.6 3.7 0.7 10.1 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF423) DUF202 PF02656.15 KFR04370.1 - 0.94 10.0 5.7 1.3e+02 3.1 5.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Sigma_reg_N PF13800.6 KFR04370.1 - 5.8 7.3 8.1 16 5.8 0.1 3.7 4 0 0 4 4 4 0 Sigma factor regulator N-terminal DctQ PF04290.12 KFR04370.1 - 6.3 6.7 8.6 0.48 10.3 0.5 2.9 2 2 1 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Ion_trans PF00520.31 KFR04371.1 - 1e-51 175.6 8.2 1.4e-51 175.1 8.2 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFR04371.1 - 2e-28 98.6 0.0 3.5e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFR04371.1 - 1.6e-14 53.6 4.7 1.6e-14 53.6 4.7 2.5 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.12 KFR04371.1 - 0.013 14.2 0.9 0.013 14.2 0.9 1.6 2 0 0 2 2 2 0 Polycystin cation channel Sigma_reg_N PF13800.6 KFR04371.1 - 0.094 13.0 0.7 10 6.5 0.0 3.5 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Ion_trans PF00520.31 KFR04372.1 - 2.2e-51 174.4 6.4 3e-51 174.0 6.4 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFR04372.1 - 1.7e-28 98.8 0.0 3e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFR04372.1 - 1.1e-13 50.9 5.8 1.1e-13 50.9 5.8 2.5 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.12 KFR04372.1 - 0.0013 17.5 0.8 0.0019 16.9 0.3 1.5 1 1 0 1 1 1 1 Polycystin cation channel SAM_PNT PF02198.16 KFR04373.1 - 1.5e-19 69.8 0.1 1.5e-19 69.7 0.1 1.0 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain BTB_3 PF16017.5 KFR04374.1 - 3.4e-49 165.3 0.0 5.4e-49 164.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 KFR04374.1 - 1.3e-05 25.5 0.0 2.7e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Pkinase PF00069.25 KFR04375.1 - 4.1e-59 200.1 0.2 4.1e-59 200.1 0.2 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR04375.1 - 3.4e-29 101.9 2.5 1.3e-20 73.8 0.2 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KFR04375.1 - 2.1e-07 31.5 1.4 5.2e-07 30.3 0.8 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KFR04375.1 - 1.6e-05 24.0 0.6 3.6e-05 22.9 0.2 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFR04375.1 - 5.8e-05 22.6 0.4 0.0015 17.9 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFR04375.1 - 0.0006 19.8 0.1 0.036 14.0 0.2 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFR04375.1 - 0.0014 18.1 0.0 0.0029 17.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KFR04375.1 - 0.094 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 MEKHLA PF08670.11 KFR04375.1 - 0.18 11.7 1.3 1.5 8.7 0.8 2.2 2 0 0 2 2 2 0 MEKHLA domain RRM_1 PF00076.22 KFR04376.1 - 3e-18 65.4 0.0 4.4e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFR04376.1 - 0.0016 18.0 0.0 0.0022 17.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFR04376.1 - 0.093 12.6 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Occluded RNA-recognition motif MAPEG PF01124.18 KFR04387.1 - 4e-15 55.9 4.1 4e-15 55.9 4.1 1.4 1 1 1 2 2 2 1 MAPEG family dNK PF01712.19 KFR04388.1 - 5.8e-64 215.7 2.6 6.5e-64 215.6 2.6 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 KFR04388.1 - 9.5e-05 22.9 0.2 0.00078 20.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFR04388.1 - 0.002 18.3 0.0 0.019 15.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KFR04388.1 - 0.013 15.2 0.1 0.075 12.7 0.1 2.1 2 1 0 2 2 2 0 Thymidylate kinase RRM_1 PF00076.22 KFR04389.1 - 4.2e-25 87.4 0.0 4.4e-13 48.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF PF08080.12 KFR04389.1 - 2.3e-13 49.9 14.6 1.1e-12 47.7 14.6 2.2 1 1 0 1 1 1 1 RNPHF zinc finger RRM_3 PF08777.11 KFR04389.1 - 0.00062 19.8 0.0 1.1 9.4 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.8 KFR04389.1 - 0.21 11.7 0.1 0.55 10.3 0.1 1.7 1 0 0 1 1 1 0 Limkain b1 RUN PF02759.19 KFR04390.1 - 5.2e-31 107.4 0.0 1.4e-30 106.0 0.0 1.8 1 0 0 1 1 1 1 RUN domain SlyX PF04102.12 KFR04390.1 - 8.3 7.1 11.6 7.4 7.3 0.4 2.9 2 0 0 2 2 2 0 SlyX Pep_M12B_propep PF01562.19 KFR04391.1 - 2e-33 115.5 0.0 5.5e-33 114.1 0.0 1.8 2 0 0 2 2 2 1 Reprolysin family propeptide ADAM_spacer1 PF05986.14 KFR04391.1 - 1.6e-25 89.4 0.0 2.9e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.19 KFR04391.1 - 6.6e-22 77.5 61.6 3.8e-10 39.8 7.5 5.8 6 0 0 6 6 6 4 Thrombospondin type 1 domain Reprolysin PF01421.19 KFR04391.1 - 1.8e-18 67.2 0.0 3.4e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 KFR04391.1 - 8e-18 64.7 16.8 2e-17 63.5 5.9 5.4 5 1 1 6 6 3 2 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 KFR04391.1 - 3.3e-14 53.5 0.1 9.4e-14 52.0 0.1 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFR04391.1 - 1.3e-10 41.8 0.1 2.9e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFR04391.1 - 2.1e-09 37.6 0.2 4.1e-09 36.6 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFR04391.1 - 5.1e-06 26.3 0.1 1e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFR04391.1 - 0.0015 18.4 0.1 0.0032 17.3 0.1 1.6 1 0 0 1 1 1 1 Matrixin PLAC PF08686.11 KFR04391.1 - 0.013 16.2 7.8 0.013 16.2 7.8 4.0 5 0 0 5 5 4 0 PLAC (protease and lacunin) domain DUF4953 PF16313.5 KFR04391.1 - 0.098 11.9 0.3 0.17 11.1 0.3 1.2 1 0 0 1 1 1 0 Met-zincin SRCR PF00530.18 KFR04392.1 - 0.069 13.7 0.9 3.7 8.1 0.2 2.5 1 1 0 2 2 2 0 Scavenger receptor cysteine-rich domain Exo_endo_phos PF03372.23 KFR04393.1 - 7.8e-21 74.7 0.0 3.3e-20 72.6 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 KFR04393.1 - 4.1e-11 42.5 12.2 9.2e-11 41.3 8.7 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFR04393.1 - 2.9e-10 40.2 17.5 2.5e-07 30.9 1.5 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFR04393.1 - 0.0058 17.0 16.1 12 6.9 0.1 5.7 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 KFR04393.1 - 0.21 11.8 17.4 1.2 9.4 0.2 4.6 4 0 0 4 4 4 0 Leucine Rich repeat SIS PF01380.22 KFR04394.1 - 1.4e-66 222.3 0.0 1.6e-36 125.0 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KFR04394.1 - 2.1e-16 60.4 0.0 4.9e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KFR04394.1 - 1.8e-13 50.5 0.0 6.6e-13 48.6 0.0 2.0 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KFR04394.1 - 2.3e-05 23.4 0.0 3.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 KFR04394.1 - 5.7e-05 22.0 0.0 0.0001 21.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 KFR04394.1 - 0.07 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 SIS domain Acetyltransf_6 PF13480.7 KFR04394.1 - 0.15 12.2 0.0 0.56 10.4 0.0 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.25 KFR04395.1 - 5.7e-64 216.0 0.0 7.1e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR04395.1 - 1.5e-29 103.1 0.1 2e-29 102.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFR04395.1 - 1.8e-06 27.5 0.3 2.9e-06 26.8 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFR04395.1 - 4.7e-05 22.8 0.1 0.001 18.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFR04395.1 - 0.00049 20.1 0.3 0.00091 19.2 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFR04395.1 - 0.00054 19.6 0.2 0.00093 18.8 0.2 1.3 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 KFR04395.1 - 0.071 12.7 0.3 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 KFR04396.1 - 3.9e-53 180.5 0.5 5.5e-53 180.0 0.5 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR04396.1 - 1.6e-25 89.9 1.3 3.9e-25 88.6 0.1 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Aminotran_3 PF00202.21 KFR04397.1 - 9.2e-83 278.1 0.0 1.1e-82 277.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KFR04397.1 - 0.00087 18.6 0.0 0.0019 17.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II RRM_1 PF00076.22 KFR04398.1 - 4.7e-34 116.0 0.3 1e-15 57.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFR04398.1 - 1.2e-17 63.8 0.5 8.8e-09 35.4 0.1 2.5 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KFR04398.1 - 4.4e-07 29.8 0.0 0.00049 20.0 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KFR04398.1 - 2.8e-05 24.1 0.1 0.1 12.7 0.1 2.4 2 0 0 2 2 2 2 RNA binding motif NID PF07292.13 KFR04398.1 - 0.0062 17.2 0.3 0.56 10.9 0.2 2.4 2 0 0 2 2 2 1 Nmi/IFP 35 domain (NID) Peptidase_M16_C PF05193.21 KFR04398.1 - 0.026 14.6 0.1 0.062 13.3 0.1 1.6 2 0 0 2 2 2 0 Peptidase M16 inactive domain FXMRP1_C_core PF12235.8 KFR04398.1 - 0.34 11.6 5.0 0.73 10.5 5.0 1.6 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal NDK PF00334.19 KFR04399.1 - 1e-35 122.7 0.0 1.3e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Dpy-30 PF05186.13 KFR04399.1 - 2.3e-18 65.6 0.5 3.6e-18 65.0 0.5 1.3 1 0 0 1 1 1 1 Dpy-30 motif wnt PF00110.19 KFR04400.1 - 9.6e-95 317.7 27.1 1.2e-94 317.4 27.1 1.0 1 0 0 1 1 1 1 wnt family Thymosin PF01290.20 KFR04401.1 - 6.3e-21 73.8 10.0 6.8e-21 73.7 10.0 1.0 1 0 0 1 1 1 1 Thymosin beta-4 family WH2 PF02205.20 KFR04401.1 - 0.014 15.2 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 WH2 motif DUF4522 PF15022.6 KFR04401.1 - 0.022 15.0 0.3 0.023 14.9 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4522) RhoGAP PF00620.27 KFR04402.1 - 6.9e-37 126.6 1.8 5.5e-36 123.7 0.0 2.9 3 0 0 3 3 3 1 RhoGAP domain Drc1-Sld2 PF11719.8 KFR04402.1 - 0.00054 19.6 9.9 0.00054 19.6 9.9 4.0 3 2 1 4 4 4 2 DNA replication and checkpoint protein DUF1732 PF08340.11 KFR04402.1 - 0.11 12.5 1.4 0.5 10.4 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1732) PilJ PF13675.6 KFR04402.1 - 0.17 11.9 4.6 1.3 9.1 1.0 2.7 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4404 PF14357.6 KFR04402.1 - 9.4 6.9 14.3 2.9 8.6 0.6 4.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) PKD_channel PF08016.12 KFR04403.1 - 6.4e-137 456.7 25.6 9.2e-137 456.2 25.6 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KFR04403.1 - 2.1e-23 82.8 33.4 2.1e-23 82.8 33.4 2.1 2 0 0 2 2 2 1 Ion transport protein I-set PF07679.16 KFR04404.1 - 3.1e-40 136.1 0.0 1.8e-20 72.8 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR04404.1 - 1.2e-27 96.3 0.0 2.1e-13 50.7 0.0 3.0 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFR04404.1 - 2.6e-15 56.5 0.0 3.8e-06 27.2 0.0 2.9 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFR04404.1 - 5.9e-14 52.0 0.1 2.5e-06 27.6 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 KFR04404.1 - 5.2e-08 33.0 0.0 0.0037 17.4 0.0 3.6 2 1 0 2 2 2 2 Immunoglobulin V-set domain Herpes_gE PF02480.16 KFR04404.1 - 0.011 14.5 0.0 0.17 10.6 0.0 2.1 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E Ig_6 PF18452.1 KFR04404.1 - 0.043 13.4 0.0 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin domain I-set PF07679.16 KFR04405.1 - 2e-18 66.3 0.0 2.9e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR04405.1 - 1.4e-08 35.2 0.0 3.1e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFR04405.1 - 7.1e-07 29.3 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFR04405.1 - 0.00026 21.3 0.0 0.00056 20.2 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFR04405.1 - 0.0017 18.5 0.0 0.01 16.0 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin V-set domain Avidin PF01382.17 KFR04407.1 - 1.5e-26 93.2 0.1 1.6e-26 93.0 0.1 1.0 1 0 0 1 1 1 1 Avidin family Avidin PF01382.17 KFR04408.1 - 7.9e-36 123.0 0.3 8.8e-36 122.9 0.3 1.0 1 0 0 1 1 1 1 Avidin family BssB_TutG PF18512.1 KFR04408.1 - 0.075 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Benzylsuccinate synthase beta subunit Avidin PF01382.17 KFR04409.1 - 8.7e-41 139.0 5.3 9.8e-41 138.8 5.3 1.0 1 0 0 1 1 1 1 Avidin family 7tm_4 PF13853.6 KFR04410.1 - 2.4e-36 125.9 10.9 2.8e-36 125.7 10.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFR04410.1 - 1.1e-19 70.8 13.3 1.5e-19 70.4 13.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4462 PF14692.6 KFR04411.1 - 0.21 11.1 0.3 0.61 9.6 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) Trypsin PF00089.26 KFR04412.1 - 8.2e-61 205.6 0.0 9.3e-61 205.5 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFR04412.1 - 2.1e-07 31.9 0.0 2.8e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_C107 PF17222.3 KFR04412.1 - 0.12 11.3 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Viral cysteine endopeptidase C107 Copine PF07002.16 KFR04424.1 - 1.9e-95 318.4 0.0 2.7e-95 318.0 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 KFR04424.1 - 1.2e-27 96.1 0.1 1.2e-13 51.2 0.1 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 KFR04424.1 - 3.3e-05 24.1 0.0 5.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 KFR04424.1 - 0.00061 20.1 0.0 0.0012 19.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Ribosomal_L3 PF00297.22 KFR04425.1 - 2.9e-54 184.5 0.4 2.6e-51 174.7 0.4 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 Pkinase PF00069.25 KFR04426.1 - 1.7e-62 211.2 0.0 3.5e-62 210.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR04426.1 - 1.4e-46 158.9 0.0 3.2e-46 157.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFR04426.1 - 0.02 14.3 0.0 0.05 13.0 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFR04426.1 - 0.034 14.1 0.1 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFR04426.1 - 0.055 12.2 0.4 0.16 10.7 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase DUF5377 PF17347.2 KFR04426.1 - 0.059 13.7 0.1 6.7 7.1 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5377) XPG_I_2 PF12813.7 KFR04427.1 - 1.2e-07 31.4 0.0 3.2e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 XPG domain containing E1-E2_ATPase PF00122.20 KFR04428.1 - 1.2e-49 168.3 0.1 1.2e-49 168.3 0.1 3.1 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFR04428.1 - 3.5e-46 157.2 4.3 3.5e-46 157.2 4.3 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFR04428.1 - 1.2e-21 78.0 2.0 5.4e-21 75.8 2.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFR04428.1 - 3.5e-16 59.0 0.0 4.6e-15 55.5 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFR04428.1 - 4.6e-13 48.6 0.0 1.1e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFR04428.1 - 0.00044 20.1 2.7 0.00091 19.0 2.7 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Peptidase_C2 PF00648.21 KFR04429.1 - 3.2e-28 98.6 0.2 8.9e-26 90.6 0.0 2.1 2 0 0 2 2 2 2 Calpain family cysteine protease MIT PF04212.18 KFR04429.1 - 1.1e-15 57.5 8.2 5.1e-13 48.9 4.1 2.4 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 KFR04429.1 - 0.074 13.3 0.1 0.47 10.8 0.1 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFR04429.1 - 0.083 13.2 1.6 0.18 12.1 1.6 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat T2SSF PF00482.23 KFR04429.1 - 0.098 12.6 1.8 0.14 12.1 0.2 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F TPR_11 PF13414.6 KFR04429.1 - 0.12 12.1 0.1 0.3 10.8 0.1 1.7 1 0 0 1 1 1 0 TPR repeat TPR_2 PF07719.17 KFR04429.1 - 0.23 11.7 0.1 0.23 11.7 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Use1 PF09753.9 KFR04429.1 - 1.6 8.4 10.1 12 5.5 10.1 2.0 1 1 0 1 1 1 0 Membrane fusion protein Use1 YtxH PF12732.7 KFR04429.1 - 2.5 8.7 5.5 1.2e+02 3.3 5.5 2.4 1 1 0 1 1 1 0 YtxH-like protein Calpain_III PF01067.22 KFR04430.1 - 1.3e-13 51.5 3.5 6.2e-08 33.0 1.4 3.4 2 2 0 2 2 2 2 Calpain large subunit, domain III SH3BP5 PF05276.14 KFR04431.1 - 1.6e-76 257.1 20.4 2.4e-76 256.6 20.4 1.2 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) DUF812 PF05667.11 KFR04431.1 - 0.051 12.5 13.9 0.079 11.8 13.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Exonuc_VII_L PF02601.15 KFR04431.1 - 0.21 11.1 11.9 0.33 10.5 11.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Peptidase_C98 PF15499.6 KFR04431.1 - 0.35 10.3 5.3 0.14 11.6 2.6 1.6 1 1 1 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase LMBR1 PF04791.16 KFR04431.1 - 1.9 7.3 5.4 2.9 6.7 5.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4735 PF15882.5 KFR04431.1 - 2 7.8 7.3 1.2 8.5 1.8 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4735) Methyltransf_12 PF08242.12 KFR04432.1 - 8.5e-18 64.9 0.1 7.5e-17 61.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFR04432.1 - 5e-15 56.0 0.0 1.2e-14 54.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFR04432.1 - 5e-14 52.5 0.0 7e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFR04432.1 - 2.1e-11 44.3 0.1 5.7e-11 42.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFR04432.1 - 7.2e-10 38.8 0.0 1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KFR04432.1 - 9.7e-05 22.0 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 KFR04432.1 - 0.00033 20.1 0.0 0.00052 19.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KFR04432.1 - 0.0011 18.5 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.18 KFR04432.1 - 0.033 13.7 0.4 4.9 6.6 0.1 2.4 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain EAF PF09816.9 KFR04433.1 - 2.2e-16 60.1 0.0 5.4e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Fmp27_WPPW PF10359.9 KFR04433.1 - 0.046 12.6 0.5 0.059 12.2 0.5 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Macoilin PF09726.9 KFR04433.1 - 8.1 4.9 7.8 8.5 4.8 7.8 1.1 1 0 0 1 1 1 0 Macoilin family DUF4581 PF15167.6 KFR04434.1 - 5.9e-49 165.5 0.5 6.5e-49 165.4 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4581) Toxin_27 PF08099.11 KFR04434.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Scorpion calcine family AIG2_2 PF13772.6 KFR04435.1 - 4.7e-30 103.8 0.1 6.1e-30 103.5 0.1 1.1 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.12 KFR04435.1 - 4.4e-06 27.3 0.0 7.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like ChaC PF04752.12 KFR04435.1 - 0.12 12.4 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 ChaC-like protein Ribosomal_L14e PF01929.17 KFR04436.1 - 8.9e-31 106.2 8.0 8.9e-31 106.2 8.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.29 KFR04436.1 - 0.0089 16.0 0.1 0.015 15.3 0.1 1.4 1 0 0 1 1 1 1 KOW motif DRY_EERY PF09750.9 KFR04436.1 - 0.2 11.9 8.0 0.28 11.4 8.0 1.2 1 0 0 1 1 1 0 Alternative splicing regulator AAA_11 PF13086.6 KFR04436.1 - 0.57 9.9 7.8 0.73 9.6 7.8 1.1 1 0 0 1 1 1 0 AAA domain FAM198 PF15051.6 KFR04437.1 - 2.3e-124 414.5 0.0 2.6e-124 414.3 0.0 1.0 1 0 0 1 1 1 1 FAM198 protein DUF563 PF04577.14 KFR04438.1 - 1.2e-20 74.6 0.1 2.4e-20 73.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Pkinase PF00069.25 KFR04439.1 - 1.2e-74 251.0 0.0 2.1e-74 250.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR04439.1 - 3.8e-42 144.3 0.0 5.5e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR04439.1 - 1e-09 38.2 0.0 6.7e-09 35.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFR04439.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DnaJ PF00226.31 KFR04443.1 - 3.9e-16 58.9 1.3 6.9e-16 58.1 1.3 1.4 1 0 0 1 1 1 1 DnaJ domain Baculo_F PF12259.8 KFR04443.1 - 0.0035 15.9 0.0 0.0039 15.8 0.0 1.0 1 0 0 1 1 1 1 Baculovirus F protein Corona_S2 PF01601.16 KFR04443.1 - 0.11 11.0 5.3 0.14 10.6 5.3 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein CCER1 PF15482.6 KFR04443.1 - 1.7 8.5 5.9 2.2 8.1 5.9 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 zf-RING_UBOX PF13445.6 KFR04444.1 - 2.6e-10 40.2 4.0 8.1e-10 38.6 4.0 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFR04444.1 - 2.9e-08 33.4 2.3 2.9e-08 33.4 2.3 2.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFR04444.1 - 6.5e-08 32.3 3.5 6.5e-08 32.3 3.5 2.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFR04444.1 - 5.3e-07 29.9 4.5 5.3e-07 29.9 4.5 3.0 3 1 0 3 3 1 1 Ring finger domain zf-RING_5 PF14634.6 KFR04444.1 - 1.4e-06 28.2 4.6 1.4e-06 28.2 4.6 2.8 3 0 0 3 3 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFR04444.1 - 1.3e-05 25.0 7.2 1.3e-05 25.0 7.2 3.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 KFR04444.1 - 1.7e-05 24.8 9.3 1.7e-05 24.8 9.3 3.6 4 0 0 4 4 4 1 B-box zinc finger zf-RING_6 PF14835.6 KFR04444.1 - 3.1e-05 23.8 0.4 3.1e-05 23.8 0.4 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KFR04444.1 - 3.3e-05 24.0 7.2 3.3e-05 24.0 7.2 3.2 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING UvrD_C PF13361.6 KFR04444.1 - 0.023 14.1 6.0 0.036 13.4 6.0 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain EzrA PF06160.12 KFR04444.1 - 0.023 12.9 12.6 0.038 12.2 12.6 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TFA2_Winged_2 PF18121.1 KFR04444.1 - 0.065 12.9 0.4 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 AGOG PF09171.10 KFR04444.1 - 0.13 11.6 1.1 0.31 10.3 0.1 1.9 1 1 1 2 2 2 0 N-glycosylase/DNA lyase zf-RING_11 PF17123.5 KFR04444.1 - 2.5 7.9 9.9 1.9 8.3 6.2 2.5 2 0 0 2 2 2 0 RING-like zinc finger DUF948 PF06103.11 KFR04444.1 - 9.5 6.6 5.5 23 5.3 1.0 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) CRF PF00473.17 KFR04445.1 - 1.7e-16 60.0 1.0 1.7e-16 60.0 1.0 2.1 2 0 0 2 2 2 1 Corticotropin-releasing factor family DUF4726 PF15855.5 KFR04445.1 - 0.021 15.0 1.2 0.035 14.3 0.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4726) DUF2981 PF11200.8 KFR04445.1 - 0.12 12.2 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Cmyb_C PF09316.10 KFR04447.1 - 6.8e-80 266.5 2.2 1.6e-79 265.3 2.2 1.7 1 0 0 1 1 1 1 C-myb, C-terminal Myb_DNA-binding PF00249.31 KFR04447.1 - 4.3e-52 174.1 17.4 4e-18 65.3 2.0 3.7 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFR04447.1 - 1.6e-39 134.0 17.7 6.8e-18 64.7 2.2 4.1 2 1 2 4 4 4 3 Myb-like DNA-binding domain LMSTEN PF07988.12 KFR04447.1 - 5.8e-26 89.7 0.5 1.2e-25 88.7 0.5 1.6 1 0 0 1 1 1 1 LMSTEN motif Myb_DNA-bind_7 PF15963.5 KFR04447.1 - 8e-08 32.1 5.3 0.00036 20.4 0.1 3.9 1 1 2 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 KFR04447.1 - 3e-06 27.2 6.0 1.3 9.1 0.2 4.5 2 1 2 4 4 4 3 SLIDE SANT_DAMP1_like PF16282.5 KFR04447.1 - 0.025 14.8 7.0 1.3 9.3 0.0 3.8 2 1 2 4 4 4 0 SANT/Myb-like domain of DAMP1 Sigma70_r4_2 PF08281.12 KFR04447.1 - 0.1 12.3 0.0 0.67 9.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 Rap1_C PF11626.8 KFR04447.1 - 0.25 11.5 10.0 0.96 9.6 0.7 4.2 2 1 2 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Spore_III_AB PF09548.10 KFR04447.1 - 0.73 9.9 3.2 1.2 9.2 0.1 2.8 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) OTU PF02338.19 KFR04448.1 - 4.2e-11 43.4 0.0 1.3e-10 41.8 0.0 1.9 1 0 0 1 1 1 1 OTU-like cysteine protease ubiquitin PF00240.23 KFR04448.1 - 0.032 14.0 0.0 0.082 12.7 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family Mut7-C PF01927.16 KFR04448.1 - 0.096 12.8 0.1 3.5 7.7 0.1 2.7 2 0 0 2 2 2 0 Mut7-C RNAse domain Zn-ribbon_8 PF09723.10 KFR04448.1 - 0.24 11.6 1.7 13 6.0 0.2 3.0 3 0 0 3 3 3 0 Zinc ribbon domain P120R PF08062.11 KFR04448.1 - 5.2 7.6 7.4 0.47 10.8 1.6 2.3 2 0 0 2 2 2 0 P120R (NUC006) repeat Pkinase PF00069.25 KFR04449.1 - 2.1e-67 227.3 0.0 2.5e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR04449.1 - 1.3e-34 119.7 0.0 1.5e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR04449.1 - 2.6e-05 23.7 0.0 9.3e-05 21.9 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 KFR04449.1 - 0.00041 21.0 0.1 0.00086 20.0 0.1 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain FTA2 PF13095.6 KFR04449.1 - 0.0013 18.4 0.1 0.25 11.0 0.1 2.1 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KFR04449.1 - 0.0068 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFR04449.1 - 0.064 12.2 0.0 0.092 11.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain MCM_lid PF17855.1 KFR04450.1 - 6.7e-09 36.1 0.4 1.2e-08 35.2 0.4 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM PF00493.23 KFR04450.1 - 0.00055 19.1 0.0 0.0011 18.1 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain HLH PF00010.26 KFR04451.1 - 1.7e-13 50.3 0.0 2.2e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain LRR_4 PF12799.7 KFR04452.1 - 4e-21 74.8 24.9 6.6e-08 32.7 3.0 5.0 3 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFR04452.1 - 4.9e-17 62.0 12.8 4.1e-09 36.2 1.3 3.0 2 1 0 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KFR04452.1 - 1.1e-16 60.3 19.8 7.5e-07 28.8 5.7 5.1 3 1 2 5 5 5 5 Leucine rich repeat LRR_1 PF00560.33 KFR04452.1 - 1.1e-08 34.5 21.0 2.3 9.1 0.1 7.4 6 2 0 6 6 6 5 Leucine Rich Repeat LRR_6 PF13516.6 KFR04452.1 - 0.00096 19.0 14.7 20 5.6 0.1 7.2 7 0 0 7 7 7 2 Leucine Rich repeat JAB PF01398.21 KFR04453.1 - 4.1e-34 117.1 0.0 6.4e-34 116.5 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 KFR04453.1 - 1.5e-24 86.8 0.6 2.4e-24 86.1 0.6 1.4 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 KFR04453.1 - 0.00013 21.7 0.0 0.0002 21.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 KFR04453.1 - 0.0034 17.5 0.1 0.007 16.4 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) Sec7 PF01369.20 KFR04455.1 - 2.4e-75 252.2 0.6 6.8e-75 250.8 0.6 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KFR04455.1 - 1.6e-49 167.9 3.4 1.6e-49 167.9 3.4 3.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KFR04455.1 - 8e-40 136.4 0.1 8e-40 136.4 0.1 3.5 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 KFR04455.1 - 8.3e-36 121.7 0.2 8.3e-36 121.7 0.2 5.0 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) Sec23_helical PF04815.15 KFR04455.1 - 0.36 10.7 1.8 16 5.4 0.0 3.1 3 0 0 3 3 3 0 Sec23/Sec24 helical domain Ufd2P_core PF10408.9 KFR04458.1 - 6.6e-149 497.4 14.5 1.1e-148 496.7 14.5 1.3 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KFR04458.1 - 2.3e-32 111.0 1.0 6.6e-32 109.5 0.6 2.1 2 0 0 2 2 2 1 U-box domain IRK_C PF17655.1 KFR04459.1 - 4.5e-69 231.5 0.0 6.9e-69 230.9 0.0 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFR04459.1 - 1.2e-52 177.5 3.2 1.7e-52 177.0 3.2 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 KFR04459.1 - 0.005 16.8 1.1 0.011 15.7 1.0 1.6 1 1 0 1 1 1 1 Ion channel 7tm_4 PF13853.6 KFR04460.1 - 7.1e-34 117.8 5.1 8e-34 117.6 5.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFR04460.1 - 2e-14 53.6 6.7 2.9e-14 53.1 6.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFR04460.1 - 0.019 14.3 2.3 0.11 11.8 2.1 2.0 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv GDNF PF02351.16 KFR04486.1 - 4.9e-44 149.2 42.3 4.4e-23 82.1 6.5 3.1 3 0 0 3 3 3 3 GDNF/GAS1 domain Kelch_1 PF01344.25 KFR04487.1 - 1.8e-27 94.7 1.9 1.2e-05 24.7 0.1 6.8 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KFR04487.1 - 4.2e-22 77.6 9.0 4e-07 30.1 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 KFR04487.1 - 1.5e-21 75.9 15.3 1.5e-05 24.9 0.0 6.3 6 0 0 6 6 6 5 Kelch motif PSI PF01437.25 KFR04487.1 - 1.3e-17 64.0 113.1 1.6e-12 47.8 10.5 7.9 7 1 0 7 7 5 5 Plexin repeat Lectin_C PF00059.21 KFR04487.1 - 1.4e-17 64.4 0.2 1.4e-17 64.4 0.2 3.4 3 0 0 3 3 2 1 Lectin C-type domain Kelch_3 PF13415.6 KFR04487.1 - 5.2e-17 61.7 6.0 0.019 15.3 0.0 7.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 KFR04487.1 - 1.3e-15 57.1 2.4 0.00097 19.1 0.0 6.8 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KFR04487.1 - 5.2e-15 54.7 5.6 0.012 15.5 0.0 6.6 6 0 0 6 6 6 4 Kelch motif CUB PF00431.20 KFR04487.1 - 7.4e-13 48.8 0.0 2.9e-12 46.9 0.0 2.1 2 0 0 2 2 1 1 CUB domain Laminin_EGF PF00053.24 KFR04487.1 - 0.0018 18.4 17.0 0.0018 18.4 17.0 8.6 6 3 2 8 8 4 2 Laminin EGF domain PSI_integrin PF17205.3 KFR04487.1 - 0.0087 15.8 8.5 0.0087 15.8 8.5 7.0 6 0 0 6 6 5 2 Integrin plexin domain TMEM100 PF16311.5 KFR04487.1 - 0.018 14.6 0.3 0.044 13.4 0.3 1.6 1 0 0 1 1 1 0 Transmembrane protein 100 SIR2_2 PF13289.6 KFR04488.1 - 0.013 15.6 1.3 0.058 13.5 0.0 2.7 3 0 0 3 3 3 0 SIR2-like domain HCO3_cotransp PF00955.21 KFR04490.1 - 1.1e-159 532.5 7.4 1.5e-159 532.1 7.4 1.2 1 0 0 1 1 1 1 HCO3- transporter family PTS_EIIA_2 PF00359.22 KFR04490.1 - 5.3e-06 26.4 0.0 0.002 18.1 0.0 2.9 3 0 0 3 3 3 2 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Band_3_cyto PF07565.13 KFR04490.1 - 3e-05 24.0 0.0 5.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Band 3 cytoplasmic domain 7tm_1 PF00001.21 KFR04491.1 - 2e-75 253.6 11.5 2.5e-75 253.2 11.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR04491.1 - 8.6e-09 35.1 11.1 1.6e-08 34.2 11.1 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFR04491.1 - 7.8e-05 22.5 4.0 7.8e-05 22.5 4.0 1.8 2 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFR04491.1 - 9.9e-05 22.1 8.8 9.9e-05 22.1 8.8 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx S8_pro-domain PF16470.5 KFR04491.1 - 0.059 14.1 0.3 0.1 13.4 0.3 1.3 1 0 0 1 1 1 0 Peptidase S8 pro-domain DUF2401 PF10287.9 KFR04491.1 - 0.16 11.6 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) Haemadin PF09065.10 KFR04491.1 - 0.19 11.5 0.4 0.51 10.2 0.2 1.8 2 0 0 2 2 2 0 Haemadin Insulin_TMD PF17870.1 KFR04491.1 - 2.9 8.0 5.8 0.58 10.3 1.4 2.2 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DDRGK PF09756.9 KFR04492.1 - 1.7e-68 230.0 31.9 2.3e-68 229.5 31.9 1.2 1 0 0 1 1 1 1 DDRGK domain PCI PF01399.27 KFR04492.1 - 0.00013 22.4 0.2 0.00025 21.5 0.1 1.5 2 0 0 2 2 1 1 PCI domain FeoC PF09012.10 KFR04492.1 - 0.00039 20.4 0.2 0.58 10.3 0.1 2.5 2 0 0 2 2 2 2 FeoC like transcriptional regulator HTH_DeoR PF08220.12 KFR04492.1 - 0.0082 15.9 0.2 2.8 7.8 0.0 2.4 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain DUF3347 PF11827.8 KFR04492.1 - 0.058 13.6 8.4 0.11 12.7 8.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Presenilin PF01080.17 KFR04492.1 - 0.43 9.3 10.7 0.46 9.2 10.7 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 KFR04492.1 - 0.57 9.3 2.3 0.63 9.2 2.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 KFR04492.1 - 2.4 6.9 12.1 3.4 6.3 12.1 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Hid1 PF12722.7 KFR04492.1 - 2.5 6.1 9.0 2.7 6.0 9.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BORG_CEP PF14957.6 KFR04492.1 - 3.3 8.9 5.8 6.8 7.9 5.8 1.7 1 0 0 1 1 1 0 Cdc42 effector Ribosomal_S25 PF03297.15 KFR04492.1 - 4.2 7.6 16.4 0.099 12.9 2.9 2.9 1 1 1 2 2 2 0 S25 ribosomal protein PPL5 PF18168.1 KFR04492.1 - 5.4 6.2 9.5 8.6 5.6 9.5 1.4 1 0 0 1 1 1 0 Prim-pol family 5 CDC45 PF02724.14 KFR04492.1 - 6.2 5.0 18.4 7.7 4.7 18.4 1.3 1 0 0 1 1 1 0 CDC45-like protein AAA_23 PF13476.6 KFR04492.1 - 7.9 6.9 19.4 15 6.1 19.4 1.5 1 0 0 1 1 1 0 AAA domain U79_P34 PF03064.16 KFR04492.1 - 8.1 5.7 21.9 17 4.7 21.9 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Vfa1 PF08432.10 KFR04492.1 - 8.5 6.7 20.0 15 5.9 20.0 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Spem1 PF15670.5 KFR04492.1 - 9.5 5.7 10.1 1.3 8.5 4.3 1.9 1 1 0 2 2 2 0 Spermatid maturation protein 1 Fez1 PF06818.15 KFR04493.1 - 5.7e-77 258.7 47.2 2.7e-74 249.9 25.0 2.3 2 0 0 2 2 2 2 Fez1 ATG16 PF08614.11 KFR04493.1 - 0.00039 20.7 8.7 0.00039 20.7 8.7 3.8 2 1 1 3 3 3 1 Autophagy protein 16 (ATG16) PKcGMP_CC PF16808.5 KFR04493.1 - 0.0018 18.1 2.2 0.0018 18.1 2.2 5.6 4 1 1 5 5 5 1 Coiled-coil N-terminus of cGMP-dependent protein kinase CALCOCO1 PF07888.11 KFR04493.1 - 0.0037 16.2 29.1 0.0037 16.2 29.1 2.2 2 0 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like PyocinActivator PF11112.8 KFR04493.1 - 0.25 11.5 1.8 4.6 7.4 0.4 2.7 2 0 0 2 2 2 0 Pyocin activator protein PrtN ERM PF00769.19 KFR04493.1 - 0.58 9.9 58.0 0.066 13.0 24.2 3.3 2 1 1 3 3 3 0 Ezrin/radixin/moesin family FAM184 PF15665.5 KFR04493.1 - 1.2 8.9 52.1 0.29 10.9 19.5 3.3 3 0 0 3 3 3 0 Family with sequence similarity 184, A and B FAST_2 PF08368.12 KFR04494.1 - 1.4e-19 70.6 0.0 4.8e-19 68.9 0.0 2.0 1 0 0 1 1 1 1 FAST kinase-like protein, subdomain 2 FAST_1 PF06743.15 KFR04494.1 - 4.4e-19 68.2 2.2 1.5e-18 66.5 0.1 3.0 4 1 1 5 5 5 1 FAST kinase-like protein, subdomain 1 RAP PF08373.10 KFR04494.1 - 7.1e-12 45.2 0.6 1.2e-11 44.5 0.6 1.4 1 0 0 1 1 1 1 RAP domain U-box PF04564.15 KFR04495.1 - 3e-26 91.4 0.1 6.8e-26 90.2 0.1 1.7 1 0 0 1 1 1 1 U-box domain zf-RING_5 PF14634.6 KFR04495.1 - 3e-05 23.9 7.3 3e-05 23.9 7.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFR04495.1 - 0.00078 19.4 4.7 0.00078 19.4 4.7 3.3 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFR04495.1 - 0.0061 16.4 6.6 0.034 14.0 6.7 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF3496 PF12001.8 KFR04495.1 - 0.0076 16.6 0.9 0.016 15.5 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3496) Prok-RING_4 PF14447.6 KFR04495.1 - 0.0087 15.9 7.1 0.032 14.1 7.1 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFR04495.1 - 0.35 11.1 12.1 0.22 11.7 8.9 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FYVE PF01363.21 KFR04495.1 - 0.44 10.7 7.3 1.9 8.7 7.3 2.2 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_10 PF16685.5 KFR04495.1 - 0.46 10.7 6.8 1.3 9.2 6.7 1.9 1 1 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_2 PF13639.6 KFR04495.1 - 3.1 8.2 14.1 0.12 12.7 6.4 2.8 3 0 0 3 3 3 0 Ring finger domain Hormone_5 PF00184.17 KFR04496.1 - 1.9e-31 108.7 25.4 1.9e-31 108.7 25.4 1.5 2 0 0 2 2 2 1 Neurohypophysial hormones, C-terminal Domain Hormone_4 PF00220.17 KFR04496.1 - 0.0012 18.5 5.0 0.0012 18.5 5.0 3.0 2 0 0 2 2 2 1 Neurohypophysial hormones, N-terminal Domain MRP-S26 PF14943.6 KFR04497.1 - 1e-32 113.4 12.8 1.1e-32 113.3 12.8 1.0 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 ERM PF00769.19 KFR04497.1 - 0.01 15.6 12.5 0.012 15.5 12.5 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Cast PF10174.9 KFR04497.1 - 0.053 11.8 10.3 0.062 11.5 10.3 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone MPM1 PF17234.2 KFR04497.1 - 0.098 12.9 2.5 0.11 12.7 2.5 1.2 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Borrelia_P83 PF05262.11 KFR04497.1 - 0.81 8.1 7.9 0.86 8.0 7.9 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Y_phosphatase PF00102.27 KFR04498.1 - 2.2e-166 551.1 10.0 6.6e-86 287.7 0.8 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 KFR04498.1 - 1.1e-09 38.2 0.1 0.00089 19.1 0.0 2.7 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFR04498.1 - 1.4e-08 35.0 0.4 0.00058 19.9 0.0 2.8 2 1 1 3 3 3 2 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFR04498.1 - 3.2e-07 30.6 0.7 0.004 17.3 0.1 3.3 3 0 0 3 3 3 2 Inositol hexakisphosphate RIFIN PF02009.16 KFR04498.1 - 0.0079 16.1 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Rifin Orf78 PF06024.12 KFR04498.1 - 0.063 13.6 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Orf78 (ac78) DUF2207 PF09972.9 KFR04498.1 - 0.074 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 KFR04498.1 - 0.097 12.6 8.2 0.62 10.0 8.2 2.2 1 1 0 1 1 1 0 TMEM154 protein family Y_phosphatase2 PF03162.13 KFR04498.1 - 0.23 11.1 2.1 3.2 7.3 0.0 3.1 3 0 0 3 3 3 0 Tyrosine phosphatase family Adeno_E3_CR2 PF02439.15 KFR04498.1 - 2.6 7.9 6.9 2.4 8.0 2.6 2.5 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Fumble PF03630.14 KFR04500.1 - 9.1e-119 396.5 0.0 1e-118 396.3 0.0 1.0 1 0 0 1 1 1 1 Fumble zf-RING_11 PF17123.5 KFR04501.1 - 3.1e-09 36.4 2.7 6e-09 35.5 2.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KFR04501.1 - 1.6e-05 25.2 2.6 2.8e-05 24.3 2.6 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_1 PF14446.6 KFR04501.1 - 0.0016 18.3 1.6 0.0026 17.6 1.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-C3HC4 PF00097.25 KFR04501.1 - 0.0035 17.2 2.8 0.0068 16.3 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFR04501.1 - 0.0049 16.7 2.2 0.0097 15.7 2.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFR04501.1 - 0.0097 15.9 2.7 0.017 15.2 2.7 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFR04501.1 - 0.017 15.1 2.1 0.028 14.4 2.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Orthoreo_P10 PF07204.11 KFR04501.1 - 0.027 14.4 0.6 0.039 13.9 0.6 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 LapA_dom PF06305.11 KFR04501.1 - 0.13 12.1 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Amino_oxidase PF01593.24 KFR04503.1 - 2.6e-79 267.6 0.0 3.5e-79 267.2 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFR04503.1 - 5e-15 55.5 0.5 1e-14 54.5 0.5 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFR04503.1 - 5.3e-06 26.3 0.0 8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFR04503.1 - 1.7e-05 24.1 1.3 2.5e-05 23.5 1.3 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KFR04503.1 - 0.00018 22.0 0.7 0.00093 19.7 0.4 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFR04503.1 - 0.00034 20.0 0.0 0.00082 18.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFR04503.1 - 0.0025 16.9 0.3 0.0038 16.4 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KFR04503.1 - 0.0029 16.4 0.2 0.0072 15.1 0.2 1.6 1 1 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KFR04503.1 - 0.0058 16.0 0.2 0.008 15.6 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KFR04503.1 - 0.0067 15.7 1.6 0.011 15.1 0.4 1.8 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KFR04503.1 - 0.007 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KFR04503.1 - 0.0087 15.3 0.1 0.017 14.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Shikimate_DH PF01488.20 KFR04503.1 - 0.0094 16.0 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 KFR04503.1 - 0.011 15.1 0.2 0.018 14.3 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFR04503.1 - 0.048 12.7 0.5 0.16 11.0 0.2 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein FMO-like PF00743.19 KFR04503.1 - 0.054 11.9 0.0 0.08 11.3 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 KFR04503.1 - 0.07 13.1 0.6 0.2 11.6 0.3 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding MCRA PF06100.11 KFR04503.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 MCRA family 3HCDH_N PF02737.18 KFR04503.1 - 0.21 11.5 0.8 6.4 6.6 0.2 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7tm_1 PF00001.21 KFR04504.1 - 3.8e-79 265.7 12.0 4.6e-79 265.5 12.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR04504.1 - 4.2e-17 62.4 6.5 7.8e-17 61.5 6.5 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFR04504.1 - 1.4e-06 28.3 14.1 1.1e-05 25.4 7.0 3.0 3 0 0 3 3 3 2 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFR04504.1 - 7.8e-06 25.7 14.1 7.8e-06 25.7 14.1 2.2 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Vinculin PF01044.19 KFR04507.1 - 8.8e-53 179.8 5.9 9.7e-53 179.7 5.9 1.0 1 0 0 1 1 1 1 Vinculin family SAWADEE PF16719.5 KFR04507.1 - 0.011 15.7 0.5 0.037 14.1 0.1 1.9 1 1 0 2 2 2 0 SAWADEE domain CorA PF01544.18 KFR04507.1 - 0.024 14.0 0.8 0.042 13.2 0.8 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF349 PF03993.12 KFR04507.1 - 0.096 13.0 2.6 1.3 9.3 0.3 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) LRR_8 PF13855.6 KFR04509.1 - 6e-51 170.1 22.9 9.3e-17 60.5 1.6 5.4 2 1 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KFR04509.1 - 6.1e-21 74.2 22.6 8.2e-06 26.1 1.6 6.5 1 1 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFR04509.1 - 1.8e-20 73.2 0.0 5.1e-10 39.4 0.0 3.0 2 1 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFR04509.1 - 1.2e-13 50.9 2.7 1.9e-05 24.3 0.3 3.3 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 KFR04509.1 - 5.9e-11 41.3 20.2 0.16 12.6 0.6 10.1 9 2 0 9 9 9 1 Leucine Rich Repeat LRR_6 PF13516.6 KFR04509.1 - 2.8e-08 33.2 17.6 2 8.6 0.0 8.5 9 0 0 9 9 9 2 Leucine Rich repeat LRRNT PF01462.18 KFR04509.1 - 0.00084 18.9 1.5 0.00084 18.9 1.5 2.7 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_12 PF18837.1 KFR04509.1 - 0.004 16.8 1.4 0.23 11.2 0.0 3.4 4 0 0 4 4 4 1 Leucine-rich repeat HemY_N PF07219.13 KFR04509.1 - 0.0075 16.5 0.3 0.013 15.7 0.3 1.4 1 0 0 1 1 1 1 HemY protein N-terminus UL97 PF06734.12 KFR04509.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 UL97 SARAF PF06682.12 KFR04509.1 - 0.064 12.9 0.3 1.3 8.6 0.1 2.1 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF5305 PF17231.2 KFR04509.1 - 0.086 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Ni_hydr_CYTB PF01292.20 KFR04509.1 - 0.093 12.3 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 HYR PF02494.16 KFR04509.1 - 0.099 13.0 0.4 0.19 12.0 0.4 1.5 1 0 0 1 1 1 0 HYR domain DUF4519 PF15012.6 KFR04509.1 - 5.1 7.3 5.3 1.4 9.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Vinculin PF01044.19 KFR04510.1 - 3.3e-213 710.8 21.4 3.7e-213 710.7 21.4 1.0 1 0 0 1 1 1 1 Vinculin family I_LWEQ PF01608.17 KFR04510.1 - 0.016 15.5 3.9 0.016 15.5 3.9 4.2 3 2 0 3 3 3 0 I/LWEQ domain DUF4872 PF16169.5 KFR04510.1 - 0.14 11.9 0.7 5.2 6.8 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4872) Baculo_gp41 PF04700.12 KFR04510.1 - 0.28 11.0 3.2 1.1 9.0 0.0 2.6 3 0 0 3 3 3 0 Structural glycoprotein p40/gp41 conserved region CoA_binding PF02629.19 KFR04514.1 - 9.7e-32 109.5 1.8 1.1e-31 109.4 0.2 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KFR04514.1 - 1.2e-22 80.4 0.1 2e-22 79.6 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KFR04514.1 - 7e-09 35.6 0.0 1.3e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KFR04514.1 - 3.4e-05 24.3 0.0 8.7e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 CoA binding domain Rib_5-P_isom_A PF06026.14 KFR04515.1 - 1.2e-66 223.6 0.0 1.4e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Sugar-bind PF04198.13 KFR04515.1 - 0.065 12.3 0.0 0.092 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain Peptidase_C93 PF06035.11 KFR04515.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial transglutaminase-like cysteine proteinase BTLCP Pkinase PF00069.25 KFR04516.1 - 1.1e-51 175.8 0.0 7.4e-38 130.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFR04516.1 - 3.5e-31 108.4 0.0 4.4e-23 81.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase PQQ_2 PF13360.6 KFR04516.1 - 1.1e-06 28.5 0.1 0.0012 18.5 0.1 2.5 1 1 1 2 2 2 2 PQQ-like domain Kinase-like PF14531.6 KFR04516.1 - 3.9e-05 23.1 0.0 0.00011 21.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFR04516.1 - 0.0013 18.1 0.2 0.004 16.5 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFR04516.1 - 0.0068 15.2 0.0 0.014 14.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase TRAP-delta PF05404.12 KFR04516.1 - 0.0092 15.5 0.4 0.15 11.5 0.1 2.2 2 0 0 2 2 2 1 Translocon-associated protein, delta subunit precursor (TRAP-delta) APH PF01636.23 KFR04516.1 - 0.017 15.0 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Flagellar_put PF12611.8 KFR04516.1 - 0.099 12.4 0.1 0.27 11.1 0.1 1.8 1 0 0 1 1 1 0 Putative flagellar PQQ_3 PF13570.6 KFR04516.1 - 0.19 12.3 0.1 8.7 7.0 0.0 3.3 4 0 0 4 4 4 0 PQQ-like domain 7tm_1 PF00001.21 KFR04517.1 - 7.3e-69 232.0 28.2 8.3e-69 231.8 28.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR04517.1 - 3.4e-08 33.2 34.1 3.4e-07 29.9 34.1 2.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFR04517.1 - 0.001 18.9 8.5 0.001 18.9 8.5 2.5 3 0 0 3 3 3 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFR04517.1 - 0.0025 17.5 31.1 0.0033 17.1 29.9 1.7 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Thr_synth_N PF14821.6 KFR04520.1 - 3.8e-23 81.5 0.0 1.5e-22 79.5 0.0 2.1 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 KFR04520.1 - 4.1e-16 59.3 0.0 1.8e-15 57.1 0.0 1.9 1 1 1 2 2 2 1 Pyridoxal-phosphate dependent enzyme DUF4715 PF15835.5 KFR04520.1 - 0.058 13.5 0.0 0.13 12.4 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4715) Glyco_transf_56 PF07429.11 KFR04520.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 4-alpha-L-fucosyltransferase glycosyl transferase group 56 Lipocalin_7 PF14651.6 KFR04521.1 - 1.9e-33 115.1 1.7 2.1e-33 115.0 1.7 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.23 KFR04521.1 - 2.3e-14 53.8 2.0 2.5e-14 53.7 2.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family SET PF00856.28 KFR04522.1 - 4.2e-13 50.0 0.0 9.2e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 KFR04522.1 - 1.8e-09 37.6 17.7 1.8e-09 37.6 17.7 2.8 2 1 0 2 2 2 1 MYND finger TPR_12 PF13424.6 KFR04522.1 - 0.0097 16.2 0.0 0.027 14.8 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-met PF12874.7 KFR04523.1 - 7.7e-32 108.7 19.3 3.3e-08 33.7 1.0 4.3 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFR04523.1 - 7.7e-18 64.3 14.5 0.00031 20.9 0.3 4.3 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 KFR04523.1 - 7.6e-07 28.8 15.5 0.058 13.2 1.3 4.4 4 0 0 4 4 4 4 U1 zinc finger zf-C2H2_2 PF12756.7 KFR04523.1 - 2.1e-05 24.8 13.0 0.19 12.1 0.2 4.1 2 2 1 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFR04523.1 - 0.0036 18.0 12.8 0.51 11.3 0.1 4.5 4 0 0 4 4 4 1 C2H2-type zinc finger DUF4639 PF15479.6 KFR04523.1 - 0.028 13.4 0.5 0.033 13.2 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) Vps39_2 PF10367.9 KFR04523.1 - 1.4 9.4 11.4 0.087 13.3 1.0 3.1 2 1 2 4 4 4 0 Vacuolar sorting protein 39 domain 2 zf-DBF PF07535.12 KFR04523.1 - 2.4 8.3 14.9 2.2 8.5 0.7 4.1 4 1 0 4 4 4 0 DBF zinc finger V-set PF07686.17 KFR04524.1 - 4.2e-20 72.0 0.3 5.4e-20 71.6 0.3 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFR04524.1 - 9.4e-05 22.9 0.5 0.00027 21.5 0.5 1.7 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFR04524.1 - 0.00018 21.5 0.1 0.00033 20.6 0.1 1.4 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFR04524.1 - 0.0033 17.6 1.3 0.0077 16.4 1.3 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFR04524.1 - 0.17 12.3 2.1 0.48 10.8 2.1 1.8 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KFR04525.1 - 6.8e-07 29.4 0.0 1e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFR04525.1 - 0.00011 22.7 0.0 0.00031 21.3 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFR04525.1 - 0.00079 19.6 0.1 0.0024 18.0 0.1 1.7 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFR04525.1 - 0.0048 16.9 0.0 0.018 15.1 0.0 2.0 1 1 1 2 2 2 1 Immunoglobulin I-set domain TMEM154 PF15102.6 KFR04525.1 - 0.025 14.5 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family CLTH PF10607.9 KFR04526.1 - 4.1e-32 111.1 0.0 7.8e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KFR04526.1 - 5.8e-06 26.2 0.2 1.3e-05 25.1 0.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFR04526.1 - 0.01 16.1 1.4 0.015 15.6 0.2 2.0 2 0 0 2 2 2 0 Ring finger domain Prok-RING_4 PF14447.6 KFR04526.1 - 0.025 14.4 1.5 0.67 9.9 0.1 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 SnoaL_4 PF13577.6 KFR04526.1 - 0.14 12.3 0.0 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 SnoaL-like domain zf-RING_5 PF14634.6 KFR04526.1 - 1.6 8.8 4.4 0.45 10.5 1.1 1.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 KFR04527.1 - 5.3e-10 39.5 9.6 5.3e-10 39.5 9.6 1.9 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 KFR04527.1 - 2.6e-09 36.6 4.7 6.2e-09 35.4 4.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFR04527.1 - 2.8e-07 30.2 9.7 6.4e-07 29.1 9.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFR04527.1 - 5.1e-06 26.4 5.5 2.2e-05 24.4 5.5 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KFR04527.1 - 1.3e-05 25.4 10.9 1.3e-05 25.4 10.9 1.8 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFR04527.1 - 1.7e-05 24.6 7.8 4.2e-05 23.3 7.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFR04527.1 - 5.3e-05 23.1 7.9 0.00014 21.7 7.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFR04527.1 - 0.0015 18.3 12.3 0.0031 17.3 12.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFR04527.1 - 0.0041 17.1 8.3 0.011 15.8 8.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFR04527.1 - 0.54 9.9 13.3 1.3 8.7 13.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Pep1_7 PF17232.2 KFR04527.1 - 0.88 10.1 4.4 1.8 9.1 1.5 2.5 2 0 0 2 2 2 0 Elicitor peptide 1-7 Snf7 PF03357.21 KFR04528.1 - 3.1e-41 140.8 17.5 3.4e-41 140.7 17.5 1.0 1 0 0 1 1 1 1 Snf7 zf-ZPR1 PF03367.13 KFR04528.1 - 0.0056 16.5 0.7 0.0056 16.5 0.7 1.7 2 0 0 2 2 2 1 ZPR1 zinc-finger domain Cauli_AT PF03233.13 KFR04528.1 - 0.41 10.6 6.3 0.066 13.1 0.5 2.0 1 1 0 2 2 2 0 Aphid transmission protein ActA PF05058.12 KFR04528.1 - 0.57 8.5 5.3 0.38 9.1 4.0 1.4 1 1 0 1 1 1 0 ActA Protein TB2_DP1_HVA22 PF03134.19 KFR04529.1 - 8e-27 93.0 10.9 1.1e-26 92.5 10.9 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2306 PF10067.9 KFR04529.1 - 0.044 14.0 0.6 0.075 13.2 0.6 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) MHCassoc_trimer PF08831.10 KFR04529.1 - 0.069 13.2 0.5 0.13 12.3 0.5 1.4 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain Ribosomal_L35p PF01632.19 KFR04530.1 - 6e-16 58.7 6.3 8.1e-16 58.3 6.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L35 IL33 PF15095.6 KFR04530.1 - 0.15 11.5 1.2 0.17 11.4 1.2 1.1 1 0 0 1 1 1 0 Interleukin 33 Mitofilin PF09731.9 KFR04531.1 - 2.7e-205 683.9 52.3 4.1e-205 683.3 52.3 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein CAV_VP3 PF04771.12 KFR04531.1 - 0.078 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Chicken anaemia virus VP-3 protein Carm_PH PF17888.1 KFR04531.1 - 3.8 7.9 6.5 26 5.2 1.7 3.1 3 0 0 3 3 3 0 Carmil pleckstrin homology domain RNA_pol_Rpb1_5 PF04998.17 KFR04532.1 - 6.8e-103 343.7 0.0 1.4e-102 342.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KFR04532.1 - 7e-70 234.6 0.0 1.8e-69 233.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KFR04532.1 - 9.8e-39 132.8 0.0 3.4e-38 131.0 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KFR04532.1 - 2e-24 85.6 0.1 1.5e-23 82.8 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.12 KFR04532.1 - 4.4e-20 72.2 11.7 3.6e-18 65.9 1.1 4.4 3 1 0 3 3 3 2 RNA polymerase Rpb1, domain 1 Pox_C7_F8A PF03287.14 KFR04532.1 - 0.057 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Poxvirus C7/F8A protein HMG_box PF00505.19 KFR04532.1 - 0.16 12.4 1.1 1.2 9.7 0.1 2.8 2 0 0 2 2 2 0 HMG (high mobility group) box BUD22 PF09073.10 KFR04532.1 - 0.22 10.8 18.2 0.4 10.0 18.2 1.4 1 0 0 1 1 1 0 BUD22 RP-C_C PF11800.8 KFR04532.1 - 0.32 11.0 4.9 0.89 9.6 4.9 1.7 1 0 0 1 1 1 0 Replication protein C C-terminal region zf-RING_4 PF14570.6 KFR04532.1 - 0.49 10.2 4.1 1.8 8.4 4.1 2.0 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Glyco_transf_29 PF00777.18 KFR04534.1 - 2.4e-76 256.7 0.0 3e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) HLH PF00010.26 KFR04535.1 - 6.8e-06 25.9 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain I-set PF07679.16 KFR04537.1 - 2e-47 159.2 0.0 1.2e-17 63.7 0.0 3.4 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR04537.1 - 9.7e-42 141.5 0.1 5.3e-15 55.8 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFR04537.1 - 3.5e-30 104.0 0.3 2.6e-11 43.5 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFR04537.1 - 3.7e-27 94.5 0.1 1.8e-11 44.2 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFR04537.1 - 8.3e-20 71.0 1.0 0.00015 21.9 0.1 5.2 3 2 0 4 4 4 3 Immunoglobulin V-set domain Ig_6 PF18452.1 KFR04537.1 - 1.5e-10 40.5 0.1 0.041 13.4 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_4 PF16680.5 KFR04537.1 - 1.8e-08 34.5 0.3 0.0029 17.8 0.1 3.7 4 0 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFR04537.1 - 4.4e-07 30.2 0.0 0.035 14.5 0.0 3.5 4 0 0 4 4 4 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KFR04537.1 - 1.1e-05 25.4 0.2 0.0017 18.4 0.0 3.0 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFR04537.1 - 4.9e-05 23.3 0.1 1.6 8.9 0.0 3.3 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 KFR04537.1 - 6.9e-05 23.0 0.0 1.1 9.5 0.0 3.2 3 0 0 3 3 3 2 Natural killer cell receptor 2B4 G6B PF15096.6 KFR04537.1 - 0.024 14.4 0.0 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 G6B family zf-RRN7 PF11781.8 KFR04537.1 - 0.029 14.1 0.2 8.3 6.2 0.0 3.5 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 V-set_CD47 PF08204.11 KFR04537.1 - 0.15 12.1 0.2 2 8.4 0.0 2.3 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain zf-RING_5 PF14634.6 KFR04539.1 - 1.3e-08 34.6 17.9 1.7e-08 34.3 15.9 2.1 2 0 0 2 2 2 1 zinc-RING finger domain DUF812 PF05667.11 KFR04539.1 - 0.0065 15.4 1.4 0.0081 15.1 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Flp_N PF03930.14 KFR04539.1 - 0.015 15.2 0.8 0.024 14.6 0.8 1.3 1 0 0 1 1 1 0 Recombinase Flp protein N-terminus DASH_Spc34 PF08657.10 KFR04539.1 - 0.023 14.5 0.4 0.027 14.3 0.4 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 Prok-RING_4 PF14447.6 KFR04539.1 - 0.04 13.8 17.9 0.26 11.2 17.7 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFR04539.1 - 0.072 13.0 17.2 0.056 13.3 14.3 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFR04539.1 - 0.2 11.7 17.4 0.11 12.5 14.5 2.2 2 1 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 KFR04539.1 - 0.25 11.7 18.0 0.22 11.9 16.0 2.1 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 KFR04539.1 - 1 9.3 16.1 7.2 6.5 16.1 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) EMP24_GP25L PF01105.24 KFR04540.1 - 3.2e-42 144.5 0.4 3.6e-42 144.4 0.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4665 PF15679.5 KFR04540.1 - 0.01 16.5 1.2 0.015 15.9 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4665) Spond_N PF06468.13 KFR04541.1 - 3e-77 259.1 0.6 4e-77 258.7 0.6 1.2 1 0 0 1 1 1 1 Spondin_N TSP_1 PF00090.19 KFR04541.1 - 0.0095 16.1 3.5 0.018 15.2 3.5 1.5 1 0 0 1 1 1 1 Thrombospondin type 1 domain 2-Hacid_dh_C PF02826.19 KFR04542.1 - 2.5e-57 193.1 0.0 3.6e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFR04542.1 - 5.6e-29 100.5 0.0 6.9e-29 100.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFR04542.1 - 1.5e-05 25.2 0.0 3.2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Cellsynth_D PF03500.13 KFR04542.1 - 0.017 15.0 0.0 0.059 13.3 0.0 1.8 2 0 0 2 2 2 0 Cellulose synthase subunit D XdhC_C PF13478.6 KFR04542.1 - 0.048 14.2 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain CLTH PF10607.9 KFR04543.1 - 6.1e-29 100.8 0.4 1e-28 100.1 0.4 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Mic1 PF07035.12 KFR04543.1 - 0.00062 19.5 1.3 0.0017 18.1 0.1 2.1 3 0 0 3 3 3 1 Colon cancer-associated protein Mic1-like zf-RING_UBOX PF13445.6 KFR04543.1 - 0.0041 17.1 0.4 0.33 11.0 0.0 2.8 2 0 0 2 2 2 1 RING-type zinc-finger TFIID_NTD2 PF04494.15 KFR04543.1 - 0.063 13.5 0.2 0.15 12.2 0.1 1.7 2 0 0 2 2 2 0 WD40 associated region in TFIID subunit, NTD2 domain LisH PF08513.11 KFR04543.1 - 0.23 11.5 0.7 0.36 10.9 0.0 1.7 2 0 0 2 2 2 0 LisH FAM53 PF15242.6 KFR04545.1 - 6.5e-104 348.0 27.2 8.9e-104 347.6 27.2 1.2 1 0 0 1 1 1 1 Family of FAM53 SNF2_N PF00176.23 KFR04549.1 - 2.2e-54 184.5 0.2 3.1e-54 184.0 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFR04549.1 - 1.3e-20 73.8 0.0 1.2e-19 70.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFR04549.1 - 3.5e-10 40.2 0.2 2.3e-09 37.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFR04549.1 - 4.9e-07 29.2 0.1 9.3e-07 28.3 0.1 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HDA2-3 PF11496.8 KFR04549.1 - 8.7e-07 28.4 1.1 0.00012 21.4 1.1 2.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 KFR04549.1 - 1.2e-06 28.5 0.0 2.9e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KFR04549.1 - 0.0012 18.6 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase SMN PF06003.12 KFR04549.1 - 0.05 12.9 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) AAA_34 PF13872.6 KFR04549.1 - 0.085 11.7 0.0 5.4 5.8 0.0 2.9 4 0 0 4 4 4 0 P-loop containing NTP hydrolase pore-1 SEC-C PF02810.15 KFR04549.1 - 0.31 11.0 8.0 0.98 9.4 8.0 1.9 1 0 0 1 1 1 0 SEC-C motif VIGSSK PF14773.6 KFR04550.1 - 4.8e-08 33.0 0.1 1.4e-07 31.6 0.1 1.8 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal HABP4_PAI-RBP1 PF04774.15 KFR04551.1 - 3e-16 60.3 14.8 3.2e-14 53.7 3.7 2.7 2 1 1 3 3 3 2 Hyaluronan / mRNA binding family IHABP4_N PF16174.5 KFR04551.1 - 4.9e-09 37.0 6.0 4.9e-09 37.0 6.0 2.6 2 1 0 2 2 2 1 Intracellular hyaluronan-binding protein 4 N-terminal DSPn PF14671.6 KFR04552.1 - 3.2e-57 192.9 3.1 3.5e-56 189.6 1.8 2.4 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KFR04552.1 - 4.4e-15 55.7 0.0 1.1e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFR04552.1 - 4.9e-06 26.8 0.0 9.9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KFR04552.1 - 3.1e-05 23.6 0.1 8.7e-05 22.2 0.1 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFR04552.1 - 0.029 14.3 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KFR04552.1 - 0.034 13.7 0.0 0.071 12.7 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family ATP12 PF07542.11 KFR04552.1 - 0.065 13.3 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 ATP12 chaperone protein AhpC-TSA_2 PF13911.6 KFR04553.1 - 3.5e-20 72.2 0.0 4.2e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KFR04553.1 - 0.0011 18.9 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFR04553.1 - 0.0012 18.6 0.0 0.0016 18.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin DUF3350 PF11830.8 KFR04554.1 - 0.00019 21.7 0.7 0.00019 21.7 0.7 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3350) MIT PF04212.18 KFR04554.1 - 0.03 14.4 1.7 0.04 14.0 1.7 1.2 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain CFC PF09443.10 KFR04555.1 - 1.1e-15 57.1 10.8 1.1e-15 57.1 10.8 2.3 3 0 0 3 3 3 1 Cripto_Frl-1_Cryptic (CFC) EGF PF00008.27 KFR04555.1 - 0.016 15.5 6.3 0.016 15.5 6.3 1.9 2 0 0 2 2 2 0 EGF-like domain EGF_2 PF07974.13 KFR04555.1 - 0.017 15.5 9.4 0.017 15.5 9.4 2.1 2 1 0 2 2 2 0 EGF-like domain LRR_8 PF13855.6 KFR04556.1 - 8.8e-26 89.5 29.3 1.1e-08 34.7 1.7 4.0 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFR04556.1 - 5.7e-19 67.9 36.4 1.8e-07 31.3 2.7 5.0 1 1 6 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFR04556.1 - 7.8e-05 22.7 13.0 5 8.1 0.4 5.6 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.6 KFR04556.1 - 0.0025 17.7 13.6 4.4 7.6 0.1 5.0 5 0 0 5 5 5 3 Leucine Rich repeat RsmF_methylt_CI PF17126.5 KFR04556.1 - 0.055 13.5 0.3 16 5.6 0.0 3.6 2 2 1 3 3 3 0 RsmF rRNA methyltransferase first C-terminal domain PINIT PF14324.6 KFR04556.1 - 0.071 13.4 0.4 0.19 12.1 0.1 1.9 2 0 0 2 2 2 0 PINIT domain Ank_4 PF13637.6 KFR04557.1 - 5e-14 52.5 0.0 6.9e-05 23.3 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFR04557.1 - 4.7e-11 43.1 0.0 9.2e-09 35.8 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFR04557.1 - 9.8e-11 41.7 0.2 7.5e-07 29.3 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFR04557.1 - 2.1e-08 33.8 0.0 0.0027 18.1 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KFR04557.1 - 7.4e-07 29.4 0.0 0.1 13.1 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat VIT PF08487.10 KFR04634.1 - 5.4e-18 65.2 0.0 7.6e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VIT_2 PF13757.6 KFR04634.1 - 3.1e-08 33.4 0.1 4.8e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain 7tm_4 PF13853.6 KFR04635.1 - 2.5e-48 165.2 21.4 2.9e-48 165.0 21.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFR04635.1 - 7.9e-26 90.9 23.5 1.1e-25 90.5 23.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR04635.1 - 1.9e-07 30.7 23.3 3.2e-07 30.0 23.2 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFR04636.1 - 2.6e-42 145.5 25.5 3e-42 145.3 25.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFR04636.1 - 1.4e-21 77.0 27.5 1.9e-21 76.6 27.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFR04637.1 - 1.6e-40 139.6 17.5 2e-40 139.3 17.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFR04637.1 - 5.2e-23 81.7 19.9 8.9e-23 80.9 19.9 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR04637.1 - 0.0011 18.4 18.5 0.0064 15.9 18.5 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx PDR_CDR PF06422.12 KFR04637.1 - 2.2 8.3 5.5 53 3.8 0.3 3.5 3 0 0 3 3 3 0 CDR ABC transporter DUF1731 PF08338.11 KFR04638.1 - 3.3e-19 68.5 0.1 7.5e-19 67.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 KFR04638.1 - 1.8e-08 34.2 0.0 7.2e-08 32.2 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFR04638.1 - 0.00056 19.8 0.2 0.0016 18.3 0.2 1.9 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KFR04638.1 - 0.029 13.8 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase KR PF08659.10 KFR04638.1 - 0.049 13.5 0.1 4.5 7.2 0.1 2.2 1 1 1 2 2 2 0 KR domain RmlD_sub_bind PF04321.17 KFR04638.1 - 0.19 10.8 0.0 0.53 9.3 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain 7tm_4 PF13853.6 KFR04639.1 - 5.6e-54 183.8 22.7 6.7e-54 183.5 22.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFR04639.1 - 1.2e-24 87.1 24.0 1.8e-24 86.5 24.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFR04640.1 - 1.9e-46 159.1 25.4 2.3e-46 158.8 25.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFR04640.1 - 9.1e-27 94.0 26.6 1.2e-26 93.7 26.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR04640.1 - 0.0014 18.1 27.4 0.002 17.5 27.4 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFR04640.1 - 0.23 11.0 29.3 1.4 8.5 29.3 2.1 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFR04641.1 - 9.1e-48 163.4 27.9 1.1e-47 163.1 27.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFR04641.1 - 1.7e-26 93.2 32.3 2.2e-26 92.8 32.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFR04642.1 - 8.9e-54 183.1 28.9 1.1e-53 182.9 28.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFR04642.1 - 4.1e-27 95.2 29.6 5.8e-27 94.7 29.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ATP-synt_8 PF00895.20 KFR04642.1 - 0.034 14.6 0.7 0.034 14.6 0.7 4.1 4 1 0 4 4 4 0 ATP synthase protein 8 SLC3A2_N PF16028.5 KFR04642.1 - 0.11 12.1 0.4 0.39 10.3 0.4 1.9 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus 7tm_4 PF13853.6 KFR04643.1 - 2.4e-44 152.2 23.2 2.7e-44 152.0 23.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFR04643.1 - 1.2e-25 90.4 25.3 1.6e-25 89.9 25.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1394 PF07159.12 KFR04643.1 - 0.25 10.5 3.0 8.7 5.5 0.8 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1394) 7tm_4 PF13853.6 KFR04644.1 - 1.5e-51 175.8 23.3 1.8e-51 175.5 23.3 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFR04644.1 - 7.4e-24 84.5 26.8 9.8e-24 84.1 26.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PRIMA1 PF16101.5 KFR04644.1 - 0.061 13.4 0.8 0.061 13.4 0.8 1.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 VHS PF00790.19 KFR04645.1 - 1.5e-18 67.0 0.2 2.8e-18 66.1 0.2 1.4 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KFR04645.1 - 5.4e-18 65.1 3.5 5.4e-18 65.1 3.5 1.9 2 0 0 2 2 2 1 GAT domain CortBP2 PF09727.9 KFR04645.1 - 0.075 12.9 0.3 0.075 12.9 0.3 1.7 2 0 0 2 2 2 0 Cortactin-binding protein-2 CtaG_Cox11 PF04442.14 KFR04646.1 - 1.1e-60 204.0 0.2 1.3e-60 203.8 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 PDZ PF00595.24 KFR04647.1 - 1.3e-11 44.7 0.1 3.4e-11 43.3 0.1 1.7 1 0 0 1 1 1 1 PDZ domain WW PF00397.26 KFR04647.1 - 1.9e-11 43.8 0.6 3.2e-11 43.1 0.6 1.4 1 0 0 1 1 1 1 WW domain PDZ_6 PF17820.1 KFR04647.1 - 5.5e-05 22.9 0.0 0.00031 20.5 0.0 2.3 2 0 0 2 2 2 1 PDZ domain DUF4407 PF14362.6 KFR04647.1 - 0.019 14.3 14.9 0.11 11.9 10.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Rota_NSP4 PF01452.16 KFR04647.1 - 0.021 14.5 0.9 0.045 13.4 0.9 1.5 1 0 0 1 1 1 0 Rotavirus non structural protein BORCS6 PF10157.9 KFR04647.1 - 0.033 14.4 2.5 0.17 12.1 0.0 2.5 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 6 Pox_A11 PF05061.13 KFR04647.1 - 0.036 13.4 4.4 0.041 13.2 2.3 1.9 1 1 1 2 2 2 0 Poxvirus A11 Protein Seryl_tRNA_N PF02403.22 KFR04647.1 - 0.43 10.8 16.8 0.22 11.8 9.7 2.9 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIVA PF05103.13 KFR04647.1 - 0.46 10.6 16.3 2.4 8.3 15.3 2.5 2 1 0 2 2 2 0 DivIVA protein zf-C4H2 PF10146.9 KFR04647.1 - 1.4 9.2 9.1 3.3 8.0 9.1 1.7 1 0 0 1 1 1 0 Zinc finger-containing protein LMBR1 PF04791.16 KFR04647.1 - 2 7.2 5.9 2.9 6.7 5.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein TPR_MLP1_2 PF07926.12 KFR04647.1 - 3 7.9 28.3 0.043 13.9 18.4 2.7 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein ISG65-75 PF11727.8 KFR04647.1 - 3 7.0 9.8 0.67 9.1 4.5 2.4 2 1 0 3 3 3 0 Invariant surface glycoprotein KxDL PF10241.9 KFR04647.1 - 3 8.2 10.8 0.72 10.2 4.2 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein H-kinase_dim PF02895.14 KFR04647.1 - 7.1 7.1 8.5 28 5.2 4.6 3.3 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain DUF1664 PF07889.12 KFR04647.1 - 8.5 6.4 16.7 0.75 9.8 5.9 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) bZIP_2 PF07716.15 KFR04648.1 - 1.1e-17 63.8 12.7 2.1e-17 62.9 12.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KFR04648.1 - 7.5e-05 22.8 9.1 0.00015 21.8 9.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor Cnn_1N PF07989.11 KFR04648.1 - 0.012 15.7 0.6 0.026 14.7 0.6 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 bZIP_Maf PF03131.17 KFR04648.1 - 0.026 15.0 7.9 0.031 14.8 7.1 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor IER PF05760.12 KFR04648.1 - 0.071 13.4 0.8 0.1 12.9 0.4 1.5 1 1 1 2 2 2 0 Immediate early response protein (IER) HlyIII PF03006.20 KFR04649.1 - 1.2e-19 70.9 22.7 1.5e-19 70.6 22.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related TMEM100 PF16311.5 KFR04650.1 - 1e-66 222.5 0.3 1.2e-66 222.4 0.3 1.0 1 0 0 1 1 1 1 Transmembrane protein 100 Neurensin PF14927.6 KFR04650.1 - 1.8e-05 24.5 1.2 0.02 14.6 0.3 2.1 1 1 1 2 2 2 2 Neurensin PIRT PF15099.6 KFR04650.1 - 0.00012 21.7 0.1 0.00014 21.4 0.1 1.2 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family Claudin_2 PF13903.6 KFR04650.1 - 0.00082 19.2 0.7 0.00097 18.9 0.7 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF2371 PF10177.9 KFR04650.1 - 0.049 13.8 0.5 0.1 12.8 0.5 1.8 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Saf_2TM PF18303.1 KFR04650.1 - 0.057 13.0 0.4 0.1 12.2 0.4 1.5 1 1 0 1 1 1 0 SAVED-fused 2TM effector domain UPF0542 PF15086.6 KFR04650.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 TMEM252 PF15664.5 KFR04650.1 - 0.36 10.6 1.7 12 5.6 0.4 2.2 1 1 1 2 2 2 0 Transmembrane protein 252 family START PF01852.19 KFR04651.1 - 4.8e-34 117.6 0.0 5.5e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 START domain DUF3074 PF11274.8 KFR04651.1 - 0.11 12.4 0.1 0.41 10.6 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3074) fn3 PF00041.21 KFR04652.1 - 5.6e-13 49.1 0.1 1.2e-12 48.0 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III domain Ank_4 PF13637.6 KFR04652.1 - 2.3e-07 31.2 0.0 1.3e-06 28.8 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFR04652.1 - 5.4e-07 29.8 0.1 0.0019 18.5 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFR04652.1 - 0.00011 22.7 0.4 0.0007 20.1 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Pur_ac_phosph_N PF16656.5 KFR04652.1 - 0.0045 17.5 0.3 0.015 15.8 0.3 1.9 1 1 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain DUF412 PF04217.13 KFR04652.1 - 0.086 12.7 0.4 0.4 10.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF412 AHH PF14412.6 KFR04652.1 - 0.3 11.2 1.4 23 5.1 0.4 2.6 2 0 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Hydin_ADK PF17213.3 KFR04653.1 - 0.63 10.3 6.2 0.091 13.0 0.8 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Noggin PF05806.12 KFR04654.1 - 2.4e-105 351.2 0.9 2.8e-105 351.0 0.9 1.0 1 0 0 1 1 1 1 Noggin RRM_1 PF00076.22 KFR04655.1 - 3.5e-14 52.4 0.0 5.1e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KFR04655.1 - 8e-12 45.5 10.4 1.7e-11 44.5 10.4 1.6 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 KFR04655.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Rho_GDI PF02115.17 KFR04656.1 - 3.6e-82 274.8 0.6 4.3e-82 274.6 0.6 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor DUF4249 PF14054.6 KFR04656.1 - 0.0086 15.7 0.1 0.0094 15.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4249) Thioredoxin PF00085.20 KFR04657.1 - 1.1e-57 192.4 1.9 2.4e-29 101.3 0.0 4.0 5 0 0 5 5 5 2 Thioredoxin Thioredoxin_6 PF13848.6 KFR04657.1 - 3.6e-51 173.7 5.8 4.7e-44 150.5 3.7 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KFR04657.1 - 1.2e-11 44.6 0.1 4.6e-06 26.2 0.0 3.2 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family ERp29_N PF07912.13 KFR04657.1 - 1.9e-10 41.0 1.3 0.28 11.3 0.1 4.3 4 0 0 4 4 4 4 ERp29, N-terminal domain Thioredoxin_2 PF13098.6 KFR04657.1 - 5.7e-10 39.6 0.2 0.0018 18.7 0.0 3.2 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFR04657.1 - 1.9e-07 31.2 0.0 0.018 15.2 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KFR04657.1 - 8.6e-07 29.2 0.1 0.027 14.8 0.0 4.3 3 2 1 4 4 4 1 Thioredoxin-like AhpC-TSA PF00578.21 KFR04657.1 - 3.7e-05 23.6 0.8 0.47 10.4 0.0 3.6 3 1 0 4 4 4 2 AhpC/TSA family Redoxin PF08534.10 KFR04657.1 - 0.0035 17.1 0.7 0.2 11.3 0.1 2.8 2 1 0 2 2 2 1 Redoxin Glutaredoxin PF00462.24 KFR04657.1 - 0.011 16.0 0.7 4.2 7.7 0.0 3.3 2 1 0 2 2 2 0 Glutaredoxin HyaE PF07449.11 KFR04657.1 - 0.015 15.2 0.0 0.19 11.7 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 KFR04657.1 - 0.066 13.0 0.0 6.9 6.5 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin TraF PF13728.6 KFR04657.1 - 0.13 12.0 0.0 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 KFR04657.1 - 0.16 12.0 0.0 6.3 6.9 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin domain Ank_5 PF13857.6 KFR04658.1 - 1.7e-15 56.9 0.1 4.7e-08 33.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFR04658.1 - 2.5e-15 56.8 0.0 2.1e-14 53.8 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFR04658.1 - 2.4e-14 53.0 0.4 1.8e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KFR04658.1 - 3.7e-14 52.9 0.0 5.5e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFR04658.1 - 6.3e-13 47.7 0.2 7.5e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat FAM195 PF14799.6 KFR04659.1 - 8.9e-08 32.4 0.0 1e-07 32.2 0.0 1.1 1 0 0 1 1 1 1 FAM195 family 7tm_2 PF00002.24 KFR04660.1 - 5e-72 242.1 16.5 7.2e-72 241.6 16.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFR04660.1 - 1.1e-15 57.7 3.9 1.1e-15 57.7 3.9 1.7 2 0 0 2 2 2 1 Hormone receptor domain Dicty_CAR PF05462.11 KFR04660.1 - 0.0079 15.4 14.3 0.011 14.9 14.3 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor TMEM43 PF07787.12 KFR04660.1 - 0.17 11.3 1.8 0.27 10.6 1.8 1.2 1 0 0 1 1 1 0 Transmembrane protein 43 Mito_carr PF00153.27 KFR04661.1 - 7.6e-42 141.2 2.9 6.2e-18 64.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Arf PF00025.21 KFR04662.1 - 8.6e-20 70.9 0.0 9.9e-20 70.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFR04662.1 - 0.0093 15.5 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KFR04662.1 - 0.026 14.3 0.1 0.03 14.1 0.1 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MMR_HSR1_Xtn PF16897.5 KFR04662.1 - 0.035 14.1 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 KFR04662.1 - 0.07 13.0 0.0 0.093 12.6 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase MARVEL PF01284.23 KFR04663.1 - 4.8e-19 68.8 14.1 6e-19 68.5 14.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain TK PF00265.18 KFR04664.1 - 1.1e-71 240.4 0.4 1.3e-71 240.1 0.4 1.0 1 0 0 1 1 1 1 Thymidine kinase Abhydrolase_3 PF07859.13 KFR04665.1 - 1.9e-11 44.2 3.4 4.7e-11 42.9 3.4 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KFR04665.1 - 3.8e-09 36.0 0.1 1.6e-05 24.0 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_6 PF12697.7 KFR04665.1 - 7e-05 23.5 2.1 9.3e-05 23.1 2.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFR04665.1 - 0.00085 18.7 0.1 0.001 18.4 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 KFR04665.1 - 0.0056 16.4 0.0 0.0072 16.0 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) LIDHydrolase PF10230.9 KFR04665.1 - 0.016 14.7 0.0 0.016 14.7 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Say1_Mug180 PF10340.9 KFR04665.1 - 0.025 13.5 0.1 0.045 12.6 0.0 1.4 1 1 0 1 1 1 0 Steryl acetyl hydrolase Lipase_3 PF01764.25 KFR04665.1 - 0.064 13.1 0.0 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.7 KFR04665.1 - 0.15 10.9 1.3 1.2 8.0 1.3 2.1 1 1 0 1 1 1 0 Chlorophyllase enzyme DUF2974 PF11187.8 KFR04665.1 - 0.2 11.2 0.0 0.26 10.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) SH2 PF00017.24 KFR04666.1 - 2.1e-10 40.6 0.0 4.1e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.16 KFR04666.1 - 1.4e-05 25.4 0.0 2.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 SOCS box Exostosin PF03016.15 KFR04666.1 - 0.0066 15.7 0.0 0.0085 15.3 0.0 1.1 1 0 0 1 1 1 1 Exostosin family PLDc_2 PF13091.6 KFR04667.1 - 2.2e-14 53.5 0.0 7.1e-06 25.9 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KFR04667.1 - 0.0071 16.5 0.9 2.2 8.6 0.2 3.6 3 1 0 3 3 3 1 Phospholipase D Active site motif Phytoreo_Pns PF05451.11 KFR04667.1 - 0.062 12.4 0.0 0.22 10.6 0.0 1.7 2 0 0 2 2 2 0 Phytoreovirus nonstructural protein Pns10/11 Sec7 PF01369.20 KFR04668.1 - 3.1e-75 251.9 0.1 4.2e-75 251.5 0.1 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 KFR04668.1 - 1.1e-29 103.1 0.1 1.9e-29 102.3 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFR04668.1 - 3.5e-06 27.4 0.0 8.1e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KFR04668.1 - 0.0041 17.2 0.2 0.024 14.7 0.2 2.2 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 KFR04668.1 - 0.016 15.4 0.0 0.085 13.1 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Pilosulin PF17499.2 KFR04668.1 - 0.019 15.1 0.0 0.053 13.7 0.0 1.7 1 0 0 1 1 1 0 Ant venom peptides GPS2_interact PF15784.5 KFR04668.1 - 0.02 15.3 2.0 0.047 14.1 2.0 1.6 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain BBS2_C PF14782.6 KFR04668.1 - 0.032 13.0 1.9 1.5 7.5 1.3 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal PH_16 PF17838.1 KFR04668.1 - 0.053 13.4 0.0 0.42 10.5 0.0 2.2 2 0 0 2 2 2 0 PH domain APG6_N PF17675.1 KFR04668.1 - 0.071 13.6 3.4 0.12 12.9 3.4 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region FlgN PF05130.12 KFR04668.1 - 0.075 13.5 1.6 0.15 12.6 1.6 1.4 1 0 0 1 1 1 0 FlgN protein NUDE_C PF04880.13 KFR04668.1 - 0.55 10.7 4.1 0.94 9.9 4.1 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region UCH PF00443.29 KFR04670.1 - 2.4e-48 164.9 0.3 2.9e-48 164.6 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFR04670.1 - 4.4e-20 72.5 0.0 6.5e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Nup35_RRM PF05172.13 KFR04670.1 - 0.044 13.7 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF2913 PF11140.8 KFR04670.1 - 0.091 12.5 0.2 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2913) DZR PF12773.7 KFR04670.1 - 1.1 9.3 5.5 2 8.5 0.8 3.0 2 1 0 2 2 2 0 Double zinc ribbon Ran_BP1 PF00638.18 KFR04714.1 - 1.9e-12 47.5 0.0 3.4e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain NAD_kinase PF01513.21 KFR04715.1 - 3e-09 36.5 0.0 4.6e-08 32.6 0.0 2.1 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KFR04715.1 - 0.0018 17.9 0.0 0.0035 16.9 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain CE2_N PF17996.1 KFR04715.1 - 0.03 14.3 0.0 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 Carbohydrate esterase 2 N-terminal TPALS PF18178.1 KFR04715.1 - 0.055 12.9 0.0 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 TIR- and PNP-associating SLOG family F-box-like PF12937.7 KFR04716.1 - 5.6e-15 55.0 3.6 1.7e-14 53.5 3.6 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFR04716.1 - 1.2e-08 34.6 3.1 1.2e-08 34.6 3.1 2.4 3 0 0 3 3 3 1 F-box domain LRR_6 PF13516.6 KFR04716.1 - 0.00034 20.4 9.4 0.13 12.4 0.0 6.7 8 0 0 8 8 8 1 Leucine Rich repeat LRR_1 PF00560.33 KFR04716.1 - 0.014 15.8 14.5 5.1 8.0 0.0 7.2 6 3 0 6 6 6 0 Leucine Rich Repeat F-box_5 PF18511.1 KFR04716.1 - 0.11 12.1 0.2 0.26 10.9 0.2 1.5 1 0 0 1 1 1 0 F-box LMBR1 PF04791.16 KFR04717.1 - 1.6e-188 627.8 25.5 1.6e-188 627.8 25.5 1.4 2 0 0 2 2 2 1 LMBR1-like membrane protein EF-hand_1 PF00036.32 KFR04718.1 - 8.9e-25 84.4 10.8 6.4e-09 34.7 0.7 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KFR04718.1 - 5.7e-23 78.8 10.1 3.4e-07 29.7 0.0 4.6 4 1 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 KFR04718.1 - 3.1e-18 66.0 10.7 2.6e-08 34.2 0.2 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KFR04718.1 - 5.6e-13 47.7 18.1 5.9e-05 22.4 2.4 5.1 5 1 1 6 6 6 3 EF hand EF-hand_8 PF13833.6 KFR04718.1 - 1.1e-12 47.5 14.0 3.1e-07 30.1 1.3 4.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 KFR04718.1 - 9.4e-05 22.3 2.5 0.086 12.8 0.1 3.0 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand YugN PF08868.10 KFR04718.1 - 0.0076 16.2 0.3 0.043 13.7 0.0 2.0 2 0 0 2 2 2 1 YugN-like family Phage_XkdX PF09693.10 KFR04718.1 - 0.036 14.1 0.6 4.1 7.5 0.0 3.0 3 0 0 3 3 3 0 Phage uncharacterised protein (Phage_XkdX) SPARC_Ca_bdg PF10591.9 KFR04718.1 - 0.068 13.5 0.1 5.9 7.2 0.0 2.8 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KFR04718.1 - 1.6 9.1 4.9 2.8 8.3 0.1 3.3 3 2 0 4 4 4 0 EF-hand domain FN3_7 PF18447.1 KFR04719.1 - 4.7e-38 129.4 5.9 8.4e-38 128.6 5.9 1.4 1 0 0 1 1 1 1 Fibronectin type III domain SRCR PF00530.18 KFR04724.1 - 9.2e-115 375.9 51.5 2.1e-33 114.8 6.5 5.0 5 0 0 5 5 5 5 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFR04724.1 - 1.2e-10 41.8 22.3 0.00049 20.6 0.2 4.8 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFR04724.1 - 3.8e-05 24.2 10.4 1.9 9.0 0.1 5.0 4 1 1 5 5 5 3 Hepsin, SRCR domain Ank_2 PF12796.7 KFR04726.1 - 4.9e-21 75.1 3.1 1.2e-12 48.2 1.7 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ion_trans PF00520.31 KFR04726.1 - 2.9e-20 72.6 21.5 4.6e-20 71.9 21.5 1.3 1 0 0 1 1 1 1 Ion transport protein Ank_3 PF13606.6 KFR04726.1 - 1.2e-18 65.2 3.1 0.0001 22.4 0.0 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KFR04726.1 - 8.7e-16 58.1 0.9 2.5e-05 24.7 0.1 4.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFR04726.1 - 4e-15 55.7 4.1 0.027 14.8 0.0 5.3 3 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KFR04726.1 - 1.1e-12 47.8 3.2 0.0048 17.3 0.1 5.1 5 0 0 5 5 5 3 Ankyrin repeat OKR_DC_1 PF01276.20 KFR04726.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Pkinase_Tyr PF07714.17 KFR04727.1 - 9.9e-96 320.0 0.0 1.4e-95 319.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.19 KFR04727.1 - 2.5e-71 239.4 0.1 3.8e-71 238.8 0.1 1.3 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.25 KFR04727.1 - 3.3e-46 157.8 0.0 4.8e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 KFR04727.1 - 1.2e-26 92.9 0.1 8.3e-16 58.1 0.1 3.1 3 0 0 3 3 3 2 Fibronectin type III domain SAM_2 PF07647.17 KFR04727.1 - 1.9e-20 72.7 0.0 3.6e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFR04727.1 - 9.2e-19 67.6 0.1 2.1e-18 66.5 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EphA2_TM PF14575.6 KFR04727.1 - 2.1e-18 67.0 0.0 4.1e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Ephrin_rec_like PF07699.13 KFR04727.1 - 2.2e-05 24.1 2.8 2.2e-05 24.1 2.8 2.5 2 0 0 2 2 2 1 Putative ephrin-receptor like Pur_ac_phosph_N PF16656.5 KFR04727.1 - 9.1e-05 23.0 0.1 0.00046 20.7 0.1 2.2 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain cEGF PF12662.7 KFR04727.1 - 0.0092 15.9 1.1 0.034 14.1 1.1 2.0 1 0 0 1 1 1 1 Complement Clr-like EGF-like Y_Y_Y PF07495.13 KFR04727.1 - 0.014 15.4 0.2 0.046 13.7 0.1 1.9 2 0 0 2 2 2 0 Y_Y_Y domain Kdo PF06293.14 KFR04727.1 - 0.026 13.9 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFR04727.1 - 0.043 12.8 0.0 0.08 11.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Interfer-bind PF09294.10 KFR04727.1 - 0.061 13.7 0.0 0.71 10.2 0.0 2.5 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III Pkinase_fungal PF17667.1 KFR04727.1 - 0.096 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase EGF_CA PF07645.15 KFR04727.1 - 9.5 6.5 6.6 11 6.4 0.5 2.7 2 0 0 2 2 2 0 Calcium-binding EGF domain C1-set PF07654.15 KFR04728.1 - 1.4e-18 67.0 0.0 1.7e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.6 KFR04728.1 - 0.00025 21.6 0.0 0.00034 21.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 KFR04728.1 - 0.047 13.8 0.0 0.061 13.4 0.0 1.2 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain ig PF00047.25 KFR04728.1 - 0.048 13.8 0.1 0.066 13.4 0.1 1.2 1 0 0 1 1 1 0 Immunoglobulin domain Laminin_G_2 PF02210.24 KFR04730.1 - 6e-24 85.0 0.4 7.8e-24 84.7 0.4 1.1 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFR04730.1 - 1.6e-14 54.2 0.0 2.1e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain F5_F8_type_C PF00754.25 KFR04730.1 - 4.2e-07 30.1 0.1 4.6e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 F5/8 type C domain Homeodomain PF00046.29 KFR04737.1 - 1.3e-68 226.7 20.5 4.2e-18 64.9 0.4 5.0 4 0 0 4 4 4 4 Homeodomain zf-C2H2_4 PF13894.6 KFR04737.1 - 1.2e-15 56.8 135.0 0.13 13.2 0.4 22.9 23 0 0 23 23 23 11 C2H2-type zinc finger zf-C2H2 PF00096.26 KFR04737.1 - 4.4e-14 52.0 152.4 0.0027 18.0 0.2 22.8 24 0 0 24 24 24 11 Zinc finger, C2H2 type Homeobox_KN PF05920.11 KFR04737.1 - 2.1e-13 49.9 3.1 0.023 14.6 0.1 4.9 4 0 0 4 4 4 4 Homeobox KN domain zf-met PF12874.7 KFR04737.1 - 1.4e-08 34.8 103.4 0.00038 20.8 0.9 16.4 17 0 0 17 17 17 8 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFR04737.1 - 5.3e-06 26.1 82.4 0.0005 19.8 0.8 11.8 11 0 0 11 11 11 5 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KFR04737.1 - 0.00048 20.4 8.2 0.00048 20.4 8.2 11.6 12 2 0 12 12 11 4 Drought induced 19 protein (Di19), zinc-binding MerR_1 PF13411.6 KFR04737.1 - 0.0026 17.8 0.2 0.047 13.8 0.0 3.1 3 0 0 3 3 3 1 MerR HTH family regulatory protein zf-C2H2_6 PF13912.6 KFR04737.1 - 0.0061 16.5 0.3 0.0061 16.5 0.3 13.9 17 0 0 17 17 17 4 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFR04737.1 - 0.0085 16.4 127.8 1.1 9.7 2.6 20.3 16 6 3 20 20 20 5 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KFR04737.1 - 0.24 11.7 115.4 0.15 12.4 0.2 18.1 19 0 0 19 19 19 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFR04737.1 - 0.47 10.3 23.2 14 5.6 1.4 6.5 6 0 0 6 6 6 0 GAGA factor Pex2_Pex12 PF04757.14 KFR04738.1 - 9.4e-37 126.8 7.4 1.3e-36 126.3 7.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.25 KFR04738.1 - 5.1e-08 32.7 8.8 5.1e-08 32.7 8.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFR04738.1 - 0.00034 20.4 5.9 0.00072 19.4 5.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFR04738.1 - 0.00066 19.7 7.6 0.00066 19.7 7.6 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFR04738.1 - 0.0014 18.4 8.5 0.0027 17.6 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFR04738.1 - 0.0017 18.1 9.4 0.0017 18.1 9.4 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFR04738.1 - 0.0056 16.8 11.9 0.013 15.6 11.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KFR04738.1 - 0.013 15.4 9.7 0.013 15.4 9.7 2.4 2 1 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 KFR04738.1 - 0.014 15.7 8.6 0.039 14.3 8.6 1.8 1 0 0 1 1 1 0 Ring finger domain RDD PF06271.12 KFR04738.1 - 0.042 14.1 0.9 0.11 12.7 0.5 1.7 1 1 1 2 2 2 0 RDD family zinc-ribbons_6 PF07191.12 KFR04738.1 - 0.053 13.5 5.1 0.15 12.0 5.1 1.8 1 0 0 1 1 1 0 zinc-ribbons RVT_1 PF00078.27 KFR04739.1 - 0.0023 17.5 0.0 0.0043 16.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PKI PF02827.16 KFR04740.1 - 1.2e-29 102.3 0.3 1.4e-29 102.1 0.3 1.1 1 0 0 1 1 1 1 cAMP-dependent protein kinase inhibitor zf-C2HC_2 PF13913.6 KFR04741.1 - 5.3e-14 51.7 7.0 1.3e-08 34.6 0.7 2.6 2 0 0 2 2 2 2 zinc-finger of a C2HC-type Zf_RING PF16744.5 KFR04741.1 - 0.0024 17.9 0.8 0.094 12.8 0.0 2.5 2 0 0 2 2 2 1 KIAA1045 RING finger DZR PF12773.7 KFR04741.1 - 0.026 14.6 12.0 0.094 12.8 2.6 3.1 3 0 0 3 3 3 0 Double zinc ribbon TRAF6_Z2 PF18048.1 KFR04741.1 - 0.11 12.6 2.0 0.14 12.2 0.3 2.0 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 UL42 PF17638.2 KFR04741.1 - 0.15 12.1 4.0 0.25 11.3 0.9 2.6 3 0 0 3 3 3 0 HCMV UL42 zf-C2H2 PF00096.26 KFR04741.1 - 0.28 11.7 14.8 0.74 10.4 0.1 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF2321 PF10083.9 KFR04741.1 - 0.82 9.3 3.1 3.5 7.2 3.2 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-C2H2_4 PF13894.6 KFR04741.1 - 1.3 10.0 0.1 0.55 11.2 0.6 4.4 5 0 0 5 5 5 0 C2H2-type zinc finger Rod_cone_degen PF15201.6 KFR04741.1 - 1.8 8.7 5.4 0.46 10.6 1.4 2.1 2 0 0 2 2 2 0 Progressive rod-cone degeneration HypA PF01155.19 KFR04741.1 - 1.9 8.5 9.2 4.7 7.3 1.9 3.0 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA MerB PF03243.15 KFR04742.1 - 0.063 13.4 0.7 0.16 12.1 0.7 1.7 1 1 0 1 1 1 0 Alkylmercury lyase Stathmin PF00836.19 KFR04743.1 - 7.2e-57 191.2 24.8 9e-57 190.8 24.8 1.1 1 0 0 1 1 1 1 Stathmin family CCDC84 PF14968.6 KFR04743.1 - 0.05 13.2 4.3 0.051 13.2 4.3 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 FmdE PF02663.14 KFR04743.1 - 0.24 11.5 5.8 1.3 9.1 5.8 2.0 1 1 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Type2_restr_D3 PF16902.5 KFR04743.1 - 1.5 8.8 4.9 9.5 6.2 0.2 2.5 1 1 0 2 2 2 0 Type-2 restriction enzyme D3 domain Exonuc_VII_L PF02601.15 KFR04743.1 - 2.6 7.5 9.9 3 7.3 9.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HLH PF00010.26 KFR04744.1 - 3.5e-17 62.1 1.1 5.6e-17 61.5 1.1 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 KFR04744.1 - 1e-11 44.8 0.0 1.7e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Hairy Orange dCache_2 PF08269.11 KFR04744.1 - 0.047 12.9 0.0 0.069 12.3 0.0 1.1 1 0 0 1 1 1 0 Cache domain MRP-S35 PF10246.9 KFR04745.1 - 5.5e-54 180.6 0.1 6.2e-54 180.4 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein MRP-S35 S1 PF00575.23 KFR04745.1 - 0.05 13.9 0.0 0.073 13.4 0.0 1.3 1 0 0 1 1 1 0 S1 RNA binding domain TPD52 PF04201.15 KFR04746.1 - 3e-75 251.3 8.4 3.4e-75 251.1 8.4 1.0 1 0 0 1 1 1 1 Tumour protein D52 family PEP-utilisers_N PF05524.13 KFR04746.1 - 0.0023 18.1 2.2 0.0039 17.3 2.2 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal Occludin_ELL PF07303.13 KFR04746.1 - 0.0029 18.3 3.0 0.29 11.9 0.1 2.3 1 1 1 2 2 2 1 Occludin homology domain Cob_adeno_trans PF01923.18 KFR04746.1 - 0.013 15.6 3.1 0.018 15.2 2.9 1.3 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Uds1 PF15456.6 KFR04746.1 - 0.018 15.2 9.8 0.036 14.2 9.8 1.6 1 1 0 1 1 1 0 Up-regulated During Septation WXG100 PF06013.12 KFR04746.1 - 0.019 15.2 5.9 0.5 10.6 0.4 2.9 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Cnn_1N PF07989.11 KFR04746.1 - 0.052 13.7 5.1 0.052 13.7 5.1 2.5 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 AAA_13 PF13166.6 KFR04746.1 - 0.076 11.6 9.0 0.41 9.2 9.1 1.8 1 1 0 1 1 1 0 AAA domain HsbA PF12296.8 KFR04746.1 - 0.088 13.2 8.0 0.25 11.8 1.0 2.6 1 1 2 3 3 3 0 Hydrophobic surface binding protein A KxDL PF10241.9 KFR04746.1 - 0.11 12.8 5.3 7.3 6.9 0.2 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein Atg14 PF10186.9 KFR04746.1 - 0.12 11.4 4.7 0.17 11.0 4.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GvpK PF05121.12 KFR04746.1 - 0.13 12.3 2.9 2 8.5 3.7 2.4 2 1 0 2 2 2 0 Gas vesicle protein K Wx5_PLAF3D7 PF09688.10 KFR04746.1 - 0.14 12.1 5.9 0.11 12.5 4.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) Ada3 PF10198.9 KFR04746.1 - 0.24 11.5 5.4 0.25 11.5 5.4 1.3 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 SlyX PF04102.12 KFR04746.1 - 0.26 11.9 4.8 14 6.3 6.8 2.7 2 1 0 2 2 1 0 SlyX OmpH PF03938.14 KFR04746.1 - 0.27 11.5 10.5 0.44 10.9 9.3 1.8 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) TBCC_N PF16752.5 KFR04746.1 - 0.28 11.6 8.2 0.056 13.9 2.7 2.1 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain DUF4795 PF16043.5 KFR04746.1 - 0.33 10.5 8.0 0.54 9.8 7.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF883 PF05957.13 KFR04746.1 - 0.47 11.1 6.7 0.86 10.2 1.2 3.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) TMPIT PF07851.13 KFR04746.1 - 0.5 9.6 6.6 0.7 9.1 6.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF1192 PF06698.11 KFR04746.1 - 0.59 10.2 6.4 1.8 8.7 4.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) Spc7 PF08317.11 KFR04746.1 - 0.59 9.0 10.0 0.7 8.7 9.4 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 KFR04746.1 - 0.62 10.1 16.7 0.17 11.9 8.4 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding FtsX_ECD PF18075.1 KFR04746.1 - 0.65 10.7 7.1 1.6 9.4 4.0 2.6 1 1 1 2 2 2 0 FtsX extracellular domain HBS1_N PF08938.10 KFR04746.1 - 0.85 10.0 4.3 2.3 8.6 4.2 1.9 1 1 0 1 1 1 0 HBS1 N-terminus FlaC_arch PF05377.11 KFR04746.1 - 0.89 10.0 5.7 8.3 6.9 1.1 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) End3 PF12761.7 KFR04746.1 - 2.5 8.2 9.9 0.67 10.1 2.4 2.1 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Prefoldin_2 PF01920.20 KFR04746.1 - 2.8 7.9 14.7 2.2 8.3 9.7 2.6 1 1 1 2 2 2 0 Prefoldin subunit Syntaxin-6_N PF09177.11 KFR04746.1 - 3.3 8.3 8.3 34 5.1 8.3 2.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal APG6_N PF17675.1 KFR04746.1 - 4.4 7.8 13.0 5.2 7.6 11.9 1.7 2 1 0 2 2 2 0 Apg6 coiled-coil region BTB PF00651.31 KFR04747.1 - 6.1e-24 84.4 0.2 9.5e-24 83.8 0.2 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_5 PF13909.6 KFR04747.1 - 4.1e-10 39.2 1.0 4.1e-10 39.2 1.0 3.2 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KFR04747.1 - 1.2e-08 35.0 16.7 0.00036 20.8 0.1 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFR04747.1 - 2.8e-05 24.3 18.5 0.007 16.8 1.9 4.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR04747.1 - 4.6e-05 23.9 13.5 0.077 13.9 1.9 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger DUF3342 PF11822.8 KFR04747.1 - 0.00013 22.1 0.2 0.00027 21.0 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Ogr_Delta PF04606.12 KFR04747.1 - 0.24 11.4 4.5 0.21 11.6 1.5 2.4 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Ribosomal_L37ae PF01780.19 KFR04747.1 - 2.6 8.2 5.7 2.6 8.2 1.4 2.4 1 1 1 2 2 2 0 Ribosomal L37ae protein family zf-C2H2_6 PF13912.6 KFR04747.1 - 3.2 7.9 5.8 4.5 7.4 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 KFR04747.1 - 3.3 8.2 12.9 0.79 10.2 0.3 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFR04747.1 - 3.8 7.9 10.8 5.8 7.3 2.6 3.0 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KFR04748.1 - 0.0072 16.7 0.6 0.02 15.3 0.1 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type MRP_L53 PF10780.9 KFR04749.1 - 1.7e-11 44.1 0.0 2.8e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 RVT_1 PF00078.27 KFR04750.1 - 0.022 14.3 0.0 0.043 13.3 0.0 1.5 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Lipocalin PF00061.23 KFR04751.1 - 2.9e-16 60.0 1.1 3.2e-16 59.8 1.1 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family PhnA PF03831.14 KFR04751.1 - 0.031 14.1 1.2 0.14 12.0 0.1 2.0 2 0 0 2 2 2 0 PhnA domain Peptidase_S80 PF07230.11 KFR04751.1 - 0.04 12.2 0.1 0.042 12.1 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) Lipocalin PF00061.23 KFR04752.1 - 1.6e-23 83.5 0.5 1.7e-23 83.4 0.5 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 KFR04752.1 - 7.2e-05 22.7 1.2 0.00011 22.1 1.2 1.3 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.23 KFR04753.1 - 2.2e-26 92.8 4.5 2.4e-26 92.7 4.5 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 KFR04753.1 - 0.00043 20.2 2.9 0.00055 19.9 2.9 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family SCVP PF17619.2 KFR04753.1 - 0.033 15.0 3.1 1.1 10.2 3.0 2.7 2 1 0 2 2 2 0 Secreted clade V proteins Inositol_P PF00459.25 KFR04754.1 - 1.7e-84 283.6 0.0 2e-84 283.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Snf7 PF03357.21 KFR04755.1 - 1.4e-42 145.2 11.6 1.9e-42 144.8 11.6 1.2 1 0 0 1 1 1 1 Snf7 SYF2 PF08231.12 KFR04755.1 - 0.00099 19.5 3.3 0.0014 19.1 2.9 1.4 1 1 0 1 1 1 1 SYF2 splicing factor DDE_Tnp_ISAZ013 PF07592.11 KFR04755.1 - 0.038 13.0 0.9 0.05 12.6 0.9 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain ABC_tran_CTD PF16326.5 KFR04755.1 - 0.53 10.6 12.3 2.9 8.2 0.4 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain RRP36 PF06102.12 KFR04755.1 - 5.2 7.0 7.9 6.4 6.7 1.2 2.2 1 1 1 2 2 2 0 rRNA biogenesis protein RRP36 PX PF00787.24 KFR04756.1 - 1.5e-19 70.0 0.0 3.5e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 PX domain DUF641 PF04859.12 KFR04756.1 - 0.00088 19.6 0.6 0.0062 16.9 0.5 2.0 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) DUF4600 PF15372.6 KFR04756.1 - 0.037 14.5 2.9 0.082 13.3 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) TPD52 PF04201.15 KFR04756.1 - 0.1 12.2 2.2 0.7 9.5 2.4 2.1 2 0 0 2 2 2 0 Tumour protein D52 family DUF1635 PF07795.11 KFR04756.1 - 4.9 6.9 12.4 0.1 12.4 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) LRRFIP PF09738.9 KFR04756.1 - 7.7 5.9 11.5 0.045 13.2 2.5 1.8 2 0 0 2 2 2 0 LRRFIP family RVT_1 PF00078.27 KFR04757.1 - 0.056 13.0 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PDGF PF00341.17 KFR04759.1 - 4.4e-26 91.0 5.6 4.4e-26 91.0 5.6 2.2 2 1 0 2 2 2 1 PDGF/VEGF domain VEGF_C PF14554.6 KFR04759.1 - 1.9e-25 88.7 14.6 1.9e-25 88.7 14.6 2.6 3 0 0 3 3 3 1 VEGF heparin-binding domain DUF3408 PF11888.8 KFR04759.1 - 0.03 14.4 1.3 0.03 14.4 1.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Ribosomal_S18 PF01084.20 KFR04760.1 - 2.5e-15 56.4 0.0 4.3e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 Radial_spoke PF04712.12 KFR04761.1 - 5.3e-06 25.7 0.0 4.9e-05 22.5 0.0 2.2 2 1 0 2 2 2 1 Radial spokehead-like protein EHN PF06441.12 KFR04763.1 - 1.5e-35 121.9 0.2 2.7e-35 121.0 0.2 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KFR04763.1 - 1.5e-24 87.0 0.0 1.3e-23 84.0 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFR04763.1 - 0.00019 22.1 0.0 0.00077 20.1 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family p31comet PF06581.12 KFR04764.1 - 2.4e-72 243.3 0.0 2.7e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 Mad1 and Cdc20-bound-Mad2 binding GTP_EFTU PF00009.27 KFR04765.1 - 1.9e-26 92.8 0.0 3.2e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KFR04765.1 - 4.2e-05 23.9 0.0 0.00017 21.9 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFR04765.1 - 0.00094 19.2 0.0 0.0027 17.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFR04765.1 - 0.0015 18.5 0.0 0.069 13.1 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 KFR04765.1 - 0.0034 17.1 0.1 19 5.0 0.0 3.4 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 KFR04765.1 - 0.027 14.6 0.1 2.2 8.3 0.2 2.4 1 1 1 2 2 2 0 Dynamin family SRPRB PF09439.10 KFR04765.1 - 0.05 13.0 0.2 6 6.3 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit GTP_EFTU_D3 PF03143.17 KFR04765.1 - 0.078 13.3 0.3 0.19 12.0 0.1 1.8 2 0 0 2 2 2 0 Elongation factor Tu C-terminal domain FeoB_N PF02421.18 KFR04765.1 - 0.08 12.5 0.1 4.3 6.8 0.1 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 KFR04765.1 - 0.13 12.0 0.1 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein zf_UBZ PF18439.1 KFR04766.1 - 1.5e-12 46.8 0.8 1.5e-12 46.8 0.8 2.3 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 KFR04766.1 - 1.8e-09 38.3 0.0 3.6e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS PF00817.20 KFR04766.1 - 2.3e-08 34.2 0.0 2.5e-07 30.8 0.0 2.4 2 0 0 2 2 2 1 impB/mucB/samB family Xpo1 PF08389.12 KFR04767.1 - 2.5e-35 121.8 3.8 5.4e-35 120.6 2.8 2.2 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 KFR04767.1 - 3.2e-05 23.7 0.0 0.00012 21.9 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain RNA_pol_A_bac PF01000.26 KFR04768.1 - 3e-30 104.9 0.0 4.8e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KFR04768.1 - 1.2e-10 40.7 0.0 1.5e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain INCENP_N PF12178.8 KFR04768.1 - 0.077 13.0 0.7 8.4 6.5 0.0 2.6 2 0 0 2 2 2 0 Chromosome passenger complex (CPC) protein INCENP N terminal Yip1 PF04893.17 KFR04769.1 - 1.8e-06 27.8 17.8 2.6e-06 27.2 17.8 1.5 1 1 0 1 1 1 1 Yip1 domain Romo1 PF10247.9 KFR04769.1 - 0.018 15.4 2.3 0.045 14.1 2.1 1.9 1 1 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 YIF1 PF03878.15 KFR04769.1 - 0.29 10.6 11.1 0.99 8.9 9.1 2.1 1 1 1 2 2 2 0 YIF1 LRR_6 PF13516.6 KFR04770.1 - 1.9e-09 36.8 9.3 0.18 11.9 0.2 7.0 7 0 0 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.33 KFR04770.1 - 8.4e-05 22.6 6.3 5.7 7.9 0.0 6.4 7 1 0 7 7 7 2 Leucine Rich Repeat LRR_4 PF12799.7 KFR04770.1 - 0.0032 17.9 9.8 11 6.6 0.1 5.6 3 3 1 5 5 5 3 Leucine Rich repeats (2 copies) Pilt PF15453.6 KFR04771.1 - 4.2e-127 424.5 28.7 1.7e-94 317.2 20.0 3.5 1 1 1 2 2 2 2 Protein incorporated later into Tight Junctions Spc7 PF08317.11 KFR04771.1 - 0.0088 15.0 13.0 0.014 14.3 12.1 1.7 1 1 1 2 2 2 1 Spc7 kinetochore protein HMMR_N PF15905.5 KFR04771.1 - 0.023 14.2 13.6 0.035 13.6 13.6 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Lebercilin PF15619.6 KFR04771.1 - 0.28 10.8 18.0 1.9 8.1 18.0 2.0 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.10 KFR04771.1 - 0.72 10.0 7.1 1 9.6 5.8 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF641 PF04859.12 KFR04771.1 - 0.9 9.9 8.0 0.16 12.3 2.6 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Syntaxin_2 PF14523.6 KFR04771.1 - 1 9.8 4.8 0.77 10.2 2.4 2.0 3 0 0 3 3 2 0 Syntaxin-like protein ATG16 PF08614.11 KFR04771.1 - 1.6 8.9 17.5 0.089 13.0 11.8 1.8 2 0 0 2 2 1 0 Autophagy protein 16 (ATG16) OmpH PF03938.14 KFR04771.1 - 1.6 9.0 11.9 0.93 9.8 9.6 1.8 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) V_ATPase_I PF01496.19 KFR04771.1 - 1.7 6.4 5.8 2.5 5.9 5.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 KFR04771.1 - 1.9 8.0 6.4 3.2 7.2 6.4 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Syntaxin-6_N PF09177.11 KFR04771.1 - 2.3 8.8 10.4 0.65 10.6 2.5 2.9 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF4407 PF14362.6 KFR04771.1 - 2.4 7.4 5.9 1.2 8.4 3.5 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HIP1_clath_bdg PF16515.5 KFR04771.1 - 3.6 8.3 15.4 0.36 11.5 10.2 2.0 2 0 0 2 2 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Tropomyosin_1 PF12718.7 KFR04771.1 - 4.9 7.3 20.5 8 6.6 10.6 2.4 1 1 1 2 2 2 0 Tropomyosin like DUF4795 PF16043.5 KFR04771.1 - 6.9 6.2 12.4 5.2 6.6 10.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) ADIP PF11559.8 KFR04771.1 - 7.7 6.6 17.7 36 4.4 6.1 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMPIT PF07851.13 KFR04771.1 - 9.4 5.4 7.1 2 7.6 3.1 1.7 1 1 0 1 1 1 0 TMPIT-like protein EGF PF00008.27 KFR04772.1 - 1.8e-29 101.6 69.1 1.3e-07 31.8 7.8 6.4 6 0 0 6 6 6 6 EGF-like domain hEGF PF12661.7 KFR04772.1 - 1.6e-17 63.4 70.0 2e-05 25.1 5.0 7.5 7 0 0 7 7 7 5 Human growth factor-like EGF EGF_2 PF07974.13 KFR04772.1 - 1e-06 29.0 91.1 0.0069 16.7 10.1 6.3 6 0 0 6 6 6 5 EGF-like domain EGF_CA PF07645.15 KFR04772.1 - 0.016 15.4 75.8 0.094 12.9 6.9 6.4 3 1 3 6 6 6 0 Calcium-binding EGF domain Laminin_EGF PF00053.24 KFR04772.1 - 0.018 15.2 70.6 0.18 12.0 3.2 6.4 2 2 4 6 6 6 0 Laminin EGF domain EGF_3 PF12947.7 KFR04772.1 - 0.054 13.7 62.4 0.11 12.7 4.9 6.6 3 2 3 6 6 6 0 EGF domain zf-C2H2_jaz PF12171.8 KFR04773.1 - 0.00019 21.6 1.9 0.00019 21.6 1.9 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFR04773.1 - 0.018 15.4 2.6 2.2 8.7 0.4 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFR04773.1 - 8.6 6.9 15.1 0.43 11.0 1.9 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF2465 PF10239.9 KFR04774.1 - 5.2e-131 436.7 0.0 6.7e-131 436.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) RasGEF PF00617.19 KFR04775.1 - 4.8e-46 157.2 0.3 7.6e-46 156.5 0.3 1.3 1 0 0 1 1 1 1 RasGEF domain C1_1 PF00130.22 KFR04775.1 - 2.3e-13 49.8 9.3 5.4e-13 48.6 9.3 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_1 PF00036.32 KFR04775.1 - 1.2e-09 37.1 5.5 0.00017 20.9 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFR04775.1 - 2.7e-09 36.2 1.4 0.0002 21.0 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFR04775.1 - 5.1e-09 35.2 0.4 0.0048 16.3 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFR04775.1 - 5.2e-09 36.4 3.4 0.00064 20.1 0.1 3.6 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.6 KFR04775.1 - 2.9e-05 23.8 1.2 0.086 12.7 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain pair RasGEF_N PF00618.20 KFR04775.1 - 0.00013 22.2 0.1 0.018 15.3 0.0 3.0 2 1 0 2 2 2 1 RasGEF N-terminal motif EGF_CA PF07645.15 KFR04776.1 - 3.1e-90 296.1 279.5 2.7e-09 37.1 6.1 19.8 19 3 2 21 21 21 15 Calcium-binding EGF domain cEGF PF12662.7 KFR04776.1 - 3.2e-47 158.0 165.6 2.1e-07 30.7 2.6 18.7 18 1 0 18 18 18 12 Complement Clr-like EGF-like TB PF00683.17 KFR04776.1 - 3.4e-45 151.6 89.9 1.4e-16 60.0 9.9 6.7 7 0 0 7 7 7 4 TB domain EGF PF00008.27 KFR04776.1 - 2e-34 117.5 257.1 0.00034 20.8 7.1 20.0 19 0 0 19 19 19 15 EGF-like domain hEGF PF12661.7 KFR04776.1 - 3.6e-16 59.1 230.1 0.00016 22.1 1.9 21.1 20 1 0 20 20 20 12 Human growth factor-like EGF EGF_3 PF12947.7 KFR04776.1 - 1.1e-13 51.1 205.4 0.0022 18.2 1.3 19.4 18 0 0 18 18 18 13 EGF domain Plasmod_Pvs28 PF06247.11 KFR04776.1 - 0.0003 21.0 13.1 0.0014 18.9 3.0 17.2 18 1 0 18 18 18 9 Pvs28 EGF domain FXa_inhibition PF14670.6 KFR04776.1 - 0.00048 20.4 24.3 0.00057 20.1 7.4 20.1 19 2 2 21 21 21 13 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 KFR04776.1 - 0.00068 19.6 0.2 0.00068 19.6 0.2 19.4 23 0 0 23 23 23 7 MSP1 EGF domain 1 TPR_2 PF07719.17 KFR04777.1 - 1.8e-17 61.9 17.4 0.00084 19.3 0.0 8.9 8 1 2 10 10 10 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFR04777.1 - 4.9e-14 51.5 12.9 0.0027 17.5 0.0 7.7 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFR04777.1 - 1.9e-12 46.4 13.2 0.00063 19.8 0.0 8.1 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFR04777.1 - 3.5e-12 46.3 0.4 2e-07 31.0 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFR04777.1 - 8.3e-12 44.9 5.8 0.17 12.8 0.0 7.7 4 2 4 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFR04777.1 - 4.1e-09 36.8 3.8 0.0012 19.4 0.2 6.9 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFR04777.1 - 1.1e-08 34.7 0.0 0.00021 20.9 0.2 4.9 4 1 1 5 5 5 1 TPR repeat TPR_17 PF13431.6 KFR04777.1 - 1.6e-08 34.3 3.3 8.4e-05 22.7 0.0 5.7 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFR04777.1 - 6.8e-07 29.5 12.9 0.25 11.7 0.5 7.2 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFR04777.1 - 1.3e-06 28.9 2.8 0.00053 20.6 0.1 4.6 4 1 1 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFR04777.1 - 2.3e-05 24.5 17.0 0.0031 17.7 0.2 5.5 4 1 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KFR04777.1 - 6.4e-05 23.3 4.5 0.88 10.3 0.0 6.9 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFR04777.1 - 0.00016 21.4 6.2 6 7.1 0.3 6.4 5 1 1 6 6 6 1 Tetratricopeptide repeat BTAD PF03704.17 KFR04777.1 - 0.0039 17.6 2.8 0.038 14.4 0.5 3.5 2 2 1 3 3 3 1 Bacterial transcriptional activator domain ChAPs PF09295.10 KFR04777.1 - 0.0057 15.7 0.0 1 8.3 0.1 2.5 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.6 KFR04777.1 - 0.017 14.4 3.6 0.45 9.7 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 KFR04777.1 - 0.05 13.3 2.5 1.3 8.7 0.0 3.8 4 1 0 4 4 4 0 26S proteasome subunit RPN7 TPR_10 PF13374.6 KFR04777.1 - 0.61 10.0 13.3 9.7 6.2 0.2 6.9 7 1 1 8 8 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFR04777.1 - 2.5 8.2 5.6 7.8 6.7 0.0 4.2 4 1 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat BIRC6 PF12356.8 KFR04778.1 - 1.9e-67 226.1 4.0 1.9e-67 226.1 4.0 2.4 3 0 0 3 3 3 1 Baculoviral IAP repeat-containing protein 6 UQ_con PF00179.26 KFR04778.1 - 1.3e-30 105.8 0.0 2.9e-30 104.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BIR PF00653.21 KFR04778.1 - 1.1e-20 74.0 3.0 2.8e-20 72.7 3.0 1.7 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain UEV PF05743.13 KFR04778.1 - 0.00011 22.0 0.0 0.0003 20.6 0.0 1.7 1 0 0 1 1 1 1 UEV domain Yip1 PF04893.17 KFR04779.1 - 2.5e-10 40.3 21.4 6e-10 39.1 21.1 1.8 1 1 0 1 1 1 1 Yip1 domain UPF0139 PF03669.13 KFR04779.1 - 0.063 13.1 0.4 0.13 12.2 0.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) CARD PF00619.21 KFR04780.1 - 2.5e-18 65.9 0.1 6.9e-18 64.5 0.1 1.8 1 0 0 1 1 1 1 Caspase recruitment domain LRR_4 PF12799.7 KFR04780.1 - 6.1e-08 32.9 11.6 0.016 15.7 0.2 4.8 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFR04780.1 - 3.1e-06 26.8 9.6 0.022 14.5 0.1 4.6 2 2 2 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 KFR04780.1 - 0.0011 18.9 5.4 0.059 13.5 0.1 4.5 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.33 KFR04780.1 - 0.1 13.2 6.6 4.4 8.2 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat BORG_CEP PF14957.6 KFR04781.1 - 9.7e-34 117.2 2.5 1.4e-33 116.7 2.5 1.2 1 0 0 1 1 1 1 Cdc42 effector PBD PF00786.28 KFR04781.1 - 4.3e-09 36.6 0.0 1.2e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain TPR_1 PF00515.28 KFR04782.1 - 5.2e-05 22.9 6.5 0.0079 16.0 1.7 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFR04782.1 - 0.00049 20.1 3.2 0.081 13.2 0.7 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat Sec16_C PF12931.7 KFR04782.1 - 0.026 14.2 0.3 0.048 13.3 0.3 1.4 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 TPR_19 PF14559.6 KFR04782.1 - 0.034 14.7 0.5 0.18 12.3 0.1 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFR04782.1 - 0.037 13.7 0.3 0.8 9.4 0.0 2.6 2 0 0 2 2 2 0 TPR repeat TPR_17 PF13431.6 KFR04782.1 - 0.039 14.3 1.8 4.7 7.8 0.4 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFR04782.1 - 0.043 14.0 11.4 0.093 12.9 0.6 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat CCDC106 PF15794.5 KFR04782.1 - 0.049 13.3 1.1 0.086 12.5 1.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SKA1 PF07160.12 KFR04782.1 - 0.074 12.9 0.4 0.13 12.1 0.4 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 TPR_6 PF13174.6 KFR04782.1 - 0.14 12.8 0.7 4.1 8.3 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Pox_Ag35 PF03286.14 KFR04782.1 - 0.27 11.0 2.1 0.42 10.4 2.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein HAD_2 PF13419.6 KFR04783.1 - 1.8e-23 83.6 0.0 2.4e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFR04783.1 - 3e-13 50.5 0.0 3.4e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFR04783.1 - 5.2e-12 45.7 0.0 1.1e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like DUF4187 PF13821.6 KFR04784.1 - 3.5e-21 74.7 1.7 3.5e-21 74.7 1.7 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KFR04784.1 - 1.3e-14 53.8 1.1 2.6e-14 52.8 1.1 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFR04784.1 - 2.2e-06 27.7 0.5 2.2e-06 27.7 0.5 2.6 2 0 0 2 2 2 1 G-patch domain DUF1840 PF08895.11 KFR04784.1 - 2.8 8.3 10.5 1.3 9.3 0.9 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) HEAT_2 PF13646.6 KFR04785.1 - 2.8e-09 37.2 11.0 0.052 13.9 0.1 7.4 5 1 1 6 6 6 3 HEAT repeats HEAT PF02985.22 KFR04785.1 - 1.9e-07 30.8 37.6 0.34 11.3 1.4 11.6 11 0 0 11 11 11 3 HEAT repeat IFRD PF05004.13 KFR04785.1 - 0.0015 17.7 9.7 0.42 9.7 1.2 5.6 6 1 0 6 6 6 2 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 KFR04785.1 - 0.0025 17.9 2.5 43 4.1 0.0 4.8 3 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 MMS22L_C PF14911.6 KFR04785.1 - 0.02 14.0 1.3 1.1 8.3 0.0 2.6 2 0 0 2 2 2 0 S-phase genomic integrity recombination mediator, C-terminal DnaB_bind PF10410.9 KFR04785.1 - 0.13 12.5 0.0 0.59 10.4 0.0 2.2 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase HisKA_3 PF07730.13 KFR04785.1 - 0.31 11.6 2.5 1.7 9.3 0.1 3.4 3 0 0 3 3 3 0 Histidine kinase WD40 PF00400.32 KFR04786.1 - 1.2e-35 120.9 10.8 3e-08 34.2 0.1 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat Striatin PF08232.12 KFR04786.1 - 5.3e-27 95.3 3.6 5.3e-27 95.3 3.6 2.8 2 2 0 2 2 2 1 Striatin family ANAPC4_WD40 PF12894.7 KFR04786.1 - 1.2e-08 35.2 0.2 0.023 15.0 0.0 5.6 3 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KFR04786.1 - 0.0058 15.4 0.0 5.4 5.6 0.0 3.2 3 0 0 3 3 3 2 Nup133 N terminal like Nup160 PF11715.8 KFR04786.1 - 0.021 13.5 0.0 3.4 6.2 0.0 2.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 VWA PF00092.28 KFR04787.1 - 4e-83 277.9 0.9 3.3e-43 147.9 0.7 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 KFR04787.1 - 5.8e-34 117.0 0.0 2.1e-15 57.3 0.0 2.6 2 0 0 2 2 2 2 von Willebrand factor type A domain LCCL PF03815.19 KFR04787.1 - 5.7e-25 87.3 0.1 1.6e-24 85.9 0.1 1.8 1 0 0 1 1 1 1 LCCL domain VWA_3 PF13768.6 KFR04787.1 - 3.9e-06 26.9 0.0 0.041 13.8 0.0 2.5 2 1 0 2 2 2 2 von Willebrand factor type A domain VWA_CoxE PF05762.14 KFR04787.1 - 6.9e-05 22.3 0.0 0.062 12.7 0.0 2.5 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein DUF1194 PF06707.11 KFR04787.1 - 0.00021 20.6 0.3 0.97 8.6 0.0 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF1194) Rxt3 PF08642.10 KFR04787.1 - 0.01 16.6 0.2 0.036 14.8 0.2 2.0 1 1 0 1 1 1 1 Histone deacetylation protein Rxt3 Mucin PF01456.17 KFR04787.1 - 1.7 8.6 23.1 3.6 7.6 23.1 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein 7tm_1 PF00001.21 KFR04788.1 - 3.3e-28 98.8 12.2 3.7e-28 98.6 12.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FEZ PF07763.13 KFR04789.1 - 2.7e-88 295.8 14.8 3.4e-88 295.5 14.8 1.1 1 0 0 1 1 1 1 FEZ-like protein SCHIP-1 PF10148.9 KFR04789.1 - 0.002 17.8 0.4 0.0035 17.0 0.4 1.5 1 0 0 1 1 1 1 Schwannomin-interacting protein 1 Gluconate_2-dh3 PF13618.6 KFR04789.1 - 0.054 13.7 0.2 0.11 12.8 0.2 1.5 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 DUF5102 PF17104.5 KFR04789.1 - 0.11 12.5 9.2 0.34 10.9 7.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5102) EURL PF06937.11 KFR04789.1 - 0.48 9.8 8.7 0.15 11.4 5.8 1.6 1 1 1 2 2 2 0 EURL protein CdiI_2 PF18593.1 KFR04789.1 - 0.83 10.3 6.4 7.3 7.3 0.3 3.0 1 1 0 2 2 2 0 CdiI immunity protein Ribosomal_L12_N PF16320.5 KFR04789.1 - 1.2 8.9 6.4 1 9.1 1.0 2.5 2 0 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain V_ATPase_I PF01496.19 KFR04789.1 - 1.5 6.6 6.8 1.8 6.4 6.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.12 KFR04789.1 - 2.7 8.5 8.7 11 6.5 0.8 3.5 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein VWC PF00093.18 KFR04790.1 - 1.8e-40 137.0 249.3 3.7e-11 43.1 14.5 15.2 9 2 6 15 15 15 6 von Willebrand factor type C domain Antistasin PF02822.14 KFR04790.1 - 3.5e-16 59.5 61.4 8.6e-07 29.5 10.2 14.8 16 2 1 17 17 17 4 Antistasin family Amnionless PF14828.6 KFR04790.1 - 0.0013 17.7 12.2 0.0013 17.7 12.2 9.1 10 0 0 10 10 10 6 Amnionless TILa PF12714.7 KFR04790.1 - 0.0055 16.6 26.6 0.0087 16.0 5.8 13.0 10 2 3 13 13 13 5 TILa domain Peptidase_C15 PF01470.17 KFR04798.1 - 1.2e-15 58.2 0.0 1.4e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 Pyroglutamyl peptidase DUF3060 PF11259.8 KFR04798.1 - 0.018 14.7 0.9 3.6 7.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3060) LSM PF01423.22 KFR04799.1 - 4.9e-17 61.4 0.0 7.1e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 LSM domain bZIP_1 PF00170.21 KFR04800.1 - 7.9e-18 64.3 17.4 9.1e-18 64.1 17.4 1.1 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KFR04800.1 - 2.8e-10 40.6 8.5 3.6e-10 40.2 8.5 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 KFR04800.1 - 1.4e-08 34.7 16.5 3.2e-08 33.5 16.5 1.6 1 1 0 1 1 1 1 Basic region leucine zipper DUF737 PF05300.11 KFR04800.1 - 0.0026 18.1 4.4 0.0036 17.7 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF737) Jun PF03957.13 KFR04800.1 - 0.0028 17.6 1.1 0.0028 17.6 1.1 1.5 2 0 0 2 2 2 1 Jun-like transcription factor ZapB PF06005.12 KFR04800.1 - 0.004 17.5 4.9 0.004 17.5 4.9 2.0 1 1 0 2 2 2 1 Cell division protein ZapB PspA_IM30 PF04012.12 KFR04800.1 - 0.0051 16.4 4.4 0.0051 16.4 4.4 1.6 1 1 1 2 2 2 1 PspA/IM30 family DUF3450 PF11932.8 KFR04800.1 - 0.0056 16.0 2.5 0.0066 15.8 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Jnk-SapK_ap_N PF09744.9 KFR04800.1 - 0.0056 16.9 6.3 0.007 16.6 6.3 1.1 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 TSC22 PF01166.18 KFR04800.1 - 0.02 15.2 2.7 0.027 14.8 1.3 1.8 1 1 1 2 2 2 0 TSC-22/dip/bun family Fib_alpha PF08702.10 KFR04800.1 - 0.027 14.7 3.4 0.035 14.3 3.4 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family NBP1 PF08537.10 KFR04800.1 - 0.028 13.8 3.4 0.035 13.5 3.4 1.2 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 FlaC_arch PF05377.11 KFR04800.1 - 0.048 14.1 2.3 0.055 13.9 1.3 1.5 2 0 0 2 2 1 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 KFR04800.1 - 0.073 13.1 3.8 0.091 12.8 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 KFR04800.1 - 0.078 13.2 5.3 0.1 12.8 5.3 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TEX13 PF15186.6 KFR04800.1 - 0.2 11.3 4.7 0.21 11.2 4.1 1.3 1 1 0 1 1 1 0 Testis-expressed sequence 13 protein family ADIP PF11559.8 KFR04800.1 - 0.2 11.7 9.4 0.3 11.2 9.4 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding KELK PF15796.5 KFR04800.1 - 0.24 11.9 8.6 0.18 12.3 6.9 1.6 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF724 PF05266.14 KFR04800.1 - 0.26 11.1 5.8 0.33 10.7 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) SlyX PF04102.12 KFR04800.1 - 0.71 10.5 4.8 0.49 11.1 1.9 2.0 1 1 1 2 2 2 0 SlyX DivIC PF04977.15 KFR04800.1 - 0.77 9.6 9.0 0.5 10.2 3.4 2.3 1 1 1 2 2 2 0 Septum formation initiator NYD-SP28_assoc PF14775.6 KFR04800.1 - 0.78 9.9 5.5 0.26 11.4 2.2 2.0 2 1 0 2 2 2 0 Sperm tail C-terminal domain DUF4315 PF14193.6 KFR04800.1 - 0.91 9.6 10.2 26 4.9 10.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4315) HMMR_C PF15908.5 KFR04800.1 - 0.95 9.7 8.2 0.32 11.3 1.5 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal YabA PF06156.13 KFR04800.1 - 0.99 10.1 5.3 4.6 7.9 4.3 1.9 1 1 1 2 2 2 0 Initiation control protein YabA Uso1_p115_C PF04871.13 KFR04800.1 - 2.4 8.5 8.4 0.81 10.1 3.9 1.7 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region PDEase_I PF00233.19 KFR04801.1 - 2.4e-92 309.0 4.9 4.5e-92 308.1 4.9 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDE4_UCR PF18100.1 KFR04801.1 - 3.4e-49 166.4 1.7 1.1e-48 164.8 1.7 1.9 1 0 0 1 1 1 1 Phosphodiesterase 4 upstream conserved regions (UCR) Ras PF00071.22 KFR04802.1 - 5.4e-61 204.9 0.8 6.2e-61 204.7 0.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR04802.1 - 7.6e-34 116.5 0.5 1.1e-33 116.0 0.5 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR04802.1 - 2e-14 53.4 0.1 2.3e-14 53.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFR04802.1 - 3.4e-05 23.4 0.0 4.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFR04802.1 - 0.00011 22.3 0.0 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFR04802.1 - 0.00055 19.4 0.1 0.00067 19.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFR04802.1 - 0.0014 18.2 0.0 0.005 16.4 0.0 1.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KFR04802.1 - 0.0082 15.7 0.0 1.1 8.8 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA_24 PF13479.6 KFR04802.1 - 0.011 15.5 0.5 0.024 14.4 0.5 1.7 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFR04802.1 - 0.022 14.6 0.0 3 7.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KFR04802.1 - 0.068 13.5 0.0 0.11 12.8 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Mpv17_PMP22 PF04117.12 KFR04803.1 - 1.6e-30 105.1 0.7 1.6e-30 105.1 0.7 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family GILT PF03227.16 KFR04804.1 - 4.6e-30 104.0 0.3 6.4e-30 103.5 0.3 1.2 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) PI3K_P85_iSH2 PF16454.5 KFR04805.1 - 1.1e-60 203.9 22.3 1.6e-60 203.3 22.3 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SH2 PF00017.24 KFR04805.1 - 6.1e-41 138.4 0.1 8.6e-20 70.6 0.0 2.7 2 0 0 2 2 2 2 SH2 domain RhoGAP PF00620.27 KFR04805.1 - 2.2e-26 92.5 1.1 2.1e-25 89.3 0.0 2.7 2 1 1 3 3 3 1 RhoGAP domain SH3_1 PF00018.28 KFR04805.1 - 9.4e-05 21.9 1.1 0.0071 15.9 0.0 3.3 4 0 0 4 4 4 1 SH3 domain SH3_9 PF14604.6 KFR04805.1 - 0.00066 19.5 0.2 0.0023 17.8 0.2 2.0 1 1 0 1 1 1 1 Variant SH3 domain ATG11 PF10377.9 KFR04805.1 - 0.022 14.8 0.8 0.022 14.8 0.8 2.0 2 0 0 2 2 2 0 Autophagy-related protein 11 BRE1 PF08647.11 KFR04805.1 - 3.2 7.9 15.4 0.14 12.2 6.7 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF1908 PF08926.11 KFR04806.1 - 1.2e-120 401.9 0.5 1.2e-120 401.9 0.5 3.2 3 0 0 3 3 2 1 Domain of unknown function (DUF1908) Pkinase PF00069.25 KFR04806.1 - 9.5e-58 195.6 0.2 2.5e-57 194.2 0.0 1.8 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR04806.1 - 1.2e-22 80.5 0.0 2.9e-22 79.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase PDZ_6 PF17820.1 KFR04806.1 - 2.4e-11 43.3 0.1 5e-11 42.3 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFR04806.1 - 2.5e-08 34.1 0.0 5.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFR04806.1 - 2.2e-06 27.9 0.0 4.9e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Kinase-like PF14531.6 KFR04806.1 - 0.00048 19.5 0.0 0.0029 17.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFR04806.1 - 0.0038 17.2 0.1 0.066 13.1 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Tricorn_PDZ PF14685.6 KFR04806.1 - 0.005 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Tricorn protease PDZ domain Haspin_kinase PF12330.8 KFR04806.1 - 0.017 14.1 0.0 0.041 12.8 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KFR04806.1 - 0.067 12.0 1.4 0.095 11.5 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Seadorna_VP7 PF07387.11 KFR04806.1 - 0.24 10.4 0.2 0.49 9.4 0.2 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_C PF00433.24 KFR04806.1 - 0.28 11.9 2.0 1.5 9.6 2.0 2.3 1 0 0 1 1 1 0 Protein kinase C terminal domain Arrestin_N PF00339.29 KFR04807.1 - 1.3e-39 135.5 0.0 5.4e-38 130.3 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KFR04807.1 - 4.8e-29 101.5 0.0 1.3e-23 83.9 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 KFR04807.1 - 0.00089 18.5 0.0 0.0044 16.3 0.0 1.9 2 0 0 2 2 2 1 Rgp1 Vps26 PF03643.15 KFR04807.1 - 0.0045 16.0 0.0 0.0053 15.8 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 DUF4601 PF15373.6 KFR04808.1 - 2.4e-63 214.7 10.9 2.9e-63 214.4 10.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4601) DGF-1_C PF11040.8 KFR04808.1 - 0.061 13.3 0.1 0.23 11.5 0.1 2.0 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus PEX11 PF05648.14 KFR04809.1 - 1.4e-40 139.1 0.0 1.6e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Nodulin-like PF06813.13 KFR04809.1 - 0.071 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Nodulin-like PDEase_I PF00233.19 KFR04809.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase PH_16 PF17838.1 KFR04810.1 - 5.7e-41 139.3 0.0 1.2e-40 138.2 0.0 1.6 1 0 0 1 1 1 1 PH domain RhoGEF PF00621.20 KFR04810.1 - 2.8e-33 115.7 3.4 2.8e-33 115.7 3.4 2.6 2 1 0 2 2 2 1 RhoGEF domain PH PF00169.29 KFR04810.1 - 6.6e-06 26.6 0.0 2.1e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 KFR04810.1 - 0.0055 16.5 0.1 0.0055 16.5 0.1 3.9 3 1 0 3 3 3 1 Pleckstrin homology domain DUF5082 PF16888.5 KFR04810.1 - 0.007 16.6 6.4 0.007 16.6 6.4 3.9 3 1 0 4 4 4 1 Domain of unknown function (DUF5082) DUF4407 PF14362.6 KFR04810.1 - 7.4 5.8 19.1 1.2 8.4 14.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Pkinase_Tyr PF07714.17 KFR04811.1 - 4.6e-95 317.8 0.0 1.1e-94 316.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Recep_L_domain PF01030.24 KFR04811.1 - 1.7e-57 192.4 1.7 1e-28 99.7 0.1 2.5 2 0 0 2 2 2 2 Receptor L domain Pkinase PF00069.25 KFR04811.1 - 6.4e-40 137.2 0.0 1.2e-39 136.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.20 KFR04811.1 - 4.7e-37 127.1 43.9 1.3e-36 125.7 43.9 1.8 1 0 0 1 1 1 1 Furin-like cysteine rich region fn3 PF00041.21 KFR04811.1 - 2.3e-21 75.9 1.7 1.2e-07 32.0 0.1 4.9 4 1 0 4 4 4 4 Fibronectin type III domain Insulin_TMD PF17870.1 KFR04811.1 - 5.9e-21 74.3 2.8 1.2e-20 73.3 2.8 1.6 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment Kinase-like PF14531.6 KFR04811.1 - 0.00074 18.9 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like B2 PF11473.8 KFR04811.1 - 0.088 12.6 0.0 0.38 10.6 0.1 2.1 2 0 0 2 2 2 0 RNA binding protein B2 Toxin_29 PF08116.11 KFR04811.1 - 4.4 7.4 17.1 0.12 12.4 9.8 2.3 2 0 0 2 2 2 0 PhTx neurotoxin family DLP_helical PF18709.1 KFR04812.1 - 0.027 13.7 8.3 0.058 12.6 0.4 2.1 2 0 0 2 2 2 0 Dynamin-like helical domain QWRF PF04484.12 KFR04812.1 - 0.033 13.9 4.8 0.041 13.6 4.8 1.1 1 0 0 1 1 1 0 QWRF family ApoLp-III PF07464.11 KFR04812.1 - 0.055 13.6 5.5 0.022 14.8 2.3 1.9 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) TED_complement PF07678.14 KFR04813.1 - 9.9e-107 356.6 0.4 1.7e-106 355.8 0.4 1.4 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_BRD PF07703.14 KFR04813.1 - 7.4e-40 136.5 0.5 2.4e-37 128.4 0.1 4.1 3 1 0 3 3 3 1 Alpha-2-macroglobulin bait region domain Methyltransf_FA PF12248.8 KFR04813.1 - 5e-33 113.5 0.6 1.6e-32 111.9 0.6 1.9 1 0 0 1 1 1 1 Farnesoic acid 0-methyl transferase A2M PF00207.22 KFR04813.1 - 1.4e-30 104.9 3.1 1e-29 102.2 0.1 3.6 3 0 0 3 3 3 1 Alpha-2-macroglobulin family A2M_recep PF07677.14 KFR04813.1 - 1.1e-26 93.3 0.0 3.3e-26 91.8 0.0 1.9 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain MG4 PF17789.1 KFR04813.1 - 5.7e-12 45.6 1.0 5e-11 42.6 0.0 3.0 3 0 0 3 3 3 1 Macroglobulin domain MG4 MG2 PF01835.19 KFR04813.1 - 2.1e-11 44.1 0.0 1.1e-10 41.8 0.0 2.3 2 0 0 2 2 2 1 MG2 domain MG3 PF17791.1 KFR04813.1 - 7.4e-11 42.2 0.0 2.5e-10 40.5 0.0 2.0 1 0 0 1 1 1 1 Macroglobulin domain MG3 Kazal_2 PF07648.15 KFR04813.1 - 4.1e-07 30.0 6.2 1.3e-06 28.4 6.2 2.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain MG1 PF17790.1 KFR04813.1 - 0.0002 21.7 0.0 0.0013 19.1 0.0 2.5 1 0 0 1 1 1 1 Macroglobulin domain MG1 Kazal_1 PF00050.21 KFR04813.1 - 0.0023 17.9 6.9 0.0069 16.4 6.9 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Rib PF08428.10 KFR04813.1 - 0.0025 17.8 0.5 0.012 15.5 0.1 2.3 2 0 0 2 2 2 1 Rib/alpha-like repeat 7tm_1 PF00001.21 KFR04814.1 - 2.1e-44 151.8 23.4 5.2e-44 150.5 23.4 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFR04814.1 - 1.8e-07 31.2 15.0 3.3e-07 30.3 15.0 1.4 1 1 0 1 1 1 1 Olfactory receptor Sin3a_C PF16879.5 KFR04815.1 - 4.7e-86 289.0 6.3 4.7e-86 289.0 6.3 2.4 2 1 0 2 2 2 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 KFR04815.1 - 5.1e-42 141.9 0.2 5.1e-42 141.9 0.2 2.2 2 0 0 2 2 2 1 Sin3 family co-repressor PAH PF02671.21 KFR04815.1 - 9.5e-42 140.9 9.1 4.7e-17 61.9 0.4 4.5 4 0 0 4 4 4 3 Paired amphipathic helix repeat Med26_C PF15693.5 KFR04817.1 - 1.2e-92 309.1 1.5 1.4e-92 308.9 1.5 1.0 1 0 0 1 1 1 1 Mediator complex subunit 26 C-terminal Pullulanase_N2 PF17967.1 KFR04817.1 - 0.0089 16.9 0.1 0.013 16.4 0.1 1.3 1 0 0 1 1 1 1 Pullulanase N2 domain SLY PF12485.8 KFR04817.1 - 0.027 15.2 1.2 0.039 14.7 1.2 1.2 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein UBD PF16455.5 KFR04817.1 - 0.052 13.8 0.1 0.17 12.1 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-binding domain TPT PF03151.16 KFR04818.1 - 1.1e-85 287.5 7.2 1.3e-85 287.3 7.2 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFR04818.1 - 2.8e-18 66.4 17.7 2.7e-09 37.3 12.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KFR04818.1 - 2e-05 24.0 14.3 2.5e-05 23.7 14.3 1.1 1 0 0 1 1 1 1 UAA transporter family TMEM234 PF10639.9 KFR04818.1 - 0.0081 16.2 7.2 0.27 11.3 0.2 2.4 2 0 0 2 2 2 2 Putative transmembrane family 234 CTD_bind PF04818.13 KFR04819.1 - 3.4e-18 66.2 2.5 4.3e-18 65.9 0.6 2.3 2 1 0 2 2 2 1 RNA polymerase II-binding domain. G-patch PF01585.23 KFR04819.1 - 1.8e-11 43.8 4.6 3.9e-11 42.6 4.6 1.6 1 0 0 1 1 1 1 G-patch domain Apt1 PF10351.9 KFR04819.1 - 0.11 11.4 13.7 0.17 10.7 13.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4614 PF15391.6 KFR04820.1 - 1.5e-20 74.0 0.5 1.6e-20 73.9 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4614) Calreticulin PF00262.18 KFR04821.1 - 5.2e-80 269.1 13.6 5.2e-60 203.2 2.3 2.1 1 1 1 2 2 2 2 Calreticulin family MDM10 PF12519.8 KFR04821.1 - 0.0012 17.8 1.2 0.0016 17.4 1.2 1.1 1 0 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 baeRF_family5 PF18846.1 KFR04821.1 - 0.054 13.7 3.0 0.12 12.6 3.0 1.5 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 5 EF-hand_4 PF12763.7 KFR04822.1 - 1.8e-42 143.5 0.0 1.2e-22 79.8 0.0 3.6 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KFR04822.1 - 1.7e-12 45.9 2.9 0.0026 17.2 0.1 4.5 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 KFR04822.1 - 3.3e-09 35.9 1.8 0.051 13.5 0.2 4.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 KFR04822.1 - 8.2e-07 29.4 0.5 0.11 12.9 0.1 4.1 3 0 0 3 3 3 2 EF-hand domain pair Macoilin PF09726.9 KFR04822.1 - 2.6e-05 23.0 17.6 3.9e-05 22.4 17.6 1.2 1 0 0 1 1 1 1 Macoilin family BicD PF09730.9 KFR04822.1 - 0.00011 20.9 28.1 0.00016 20.3 28.1 1.2 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D EzrA PF06160.12 KFR04822.1 - 0.00057 18.2 39.8 0.0017 16.6 39.8 1.6 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA DUF4201 PF13870.6 KFR04822.1 - 0.0007 19.4 15.2 0.0007 19.4 15.2 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) EF-hand_5 PF13202.6 KFR04822.1 - 0.0008 18.8 3.5 0.38 10.3 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFR04822.1 - 0.00091 19.0 1.8 0.16 11.9 0.2 3.6 4 0 0 4 4 4 1 EF-hand domain pair CALCOCO1 PF07888.11 KFR04822.1 - 0.002 17.1 34.9 0.0037 16.2 34.9 1.3 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Tropomyosin PF00261.20 KFR04822.1 - 0.0022 17.4 20.4 0.0022 17.4 20.4 2.6 2 1 1 3 3 2 1 Tropomyosin EF-hand_9 PF14658.6 KFR04822.1 - 0.0031 17.8 0.3 0.24 11.8 0.0 3.5 4 0 0 4 4 2 1 EF-hand domain Spc7 PF08317.11 KFR04822.1 - 0.0046 15.9 46.7 0.034 13.0 23.2 2.4 1 1 1 2 2 2 2 Spc7 kinetochore protein Atg14 PF10186.9 KFR04822.1 - 0.01 15.0 41.6 0.14 11.2 7.9 3.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4763 PF15960.5 KFR04822.1 - 0.099 11.9 41.2 0.02 14.2 9.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) Prominin PF05478.11 KFR04822.1 - 0.1 10.5 24.0 0.15 9.9 24.0 1.1 1 0 0 1 1 1 0 Prominin DUF948 PF06103.11 KFR04822.1 - 0.16 12.2 19.7 1.3 9.4 3.1 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 KFR04822.1 - 0.21 11.6 30.7 0.032 14.3 5.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) HMMR_N PF15905.5 KFR04822.1 - 0.27 10.7 46.0 0.67 9.4 17.0 2.4 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF745 PF05335.13 KFR04822.1 - 0.28 10.9 33.8 2.4 7.9 19.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) ATG16 PF08614.11 KFR04822.1 - 0.48 10.6 55.4 0.35 11.1 32.2 3.1 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.6 KFR04822.1 - 0.6 8.7 32.8 5.7 5.5 33.0 1.9 1 1 0 1 1 1 0 AAA domain LMBR1 PF04791.16 KFR04822.1 - 0.62 8.9 21.1 1 8.2 21.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein IFT57 PF10498.9 KFR04822.1 - 0.77 8.7 38.3 3.4 6.6 9.1 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 TMPIT PF07851.13 KFR04822.1 - 0.81 8.9 34.7 1.1 8.4 15.1 2.2 1 1 1 2 2 2 0 TMPIT-like protein FUSC PF04632.12 KFR04822.1 - 0.98 7.9 6.8 1.6 7.2 6.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fez1 PF06818.15 KFR04822.1 - 1.4 9.3 47.5 0.46 10.9 22.8 2.7 2 1 1 3 3 3 0 Fez1 MAD PF05557.13 KFR04822.1 - 1.5 7.1 45.8 4 5.7 45.8 1.7 1 1 0 1 1 1 0 Mitotic checkpoint protein zf-C4H2 PF10146.9 KFR04822.1 - 2.5 8.4 36.9 0.022 15.1 11.9 3.1 2 1 1 3 3 3 0 Zinc finger-containing protein DUF3584 PF12128.8 KFR04822.1 - 3.4 5.1 38.8 0.053 11.1 31.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) GAS PF13851.6 KFR04822.1 - 3.8 6.8 45.2 2.9 7.2 18.4 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Med30 PF11315.8 KFR04822.1 - 4 7.6 29.4 1.1 9.5 23.3 2.7 1 1 2 3 3 3 0 Mediator complex subunit 30 Filament PF00038.21 KFR04822.1 - 5.7 6.4 42.4 1.2 8.7 11.3 2.7 1 1 1 2 2 2 0 Intermediate filament protein CREPT PF16566.5 KFR04822.1 - 6.5 6.9 32.1 8.8 6.5 16.2 3.4 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour DUF812 PF05667.11 KFR04822.1 - 9.1 5.0 43.3 37 3.0 19.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF812) zf-C2H2 PF00096.26 KFR04823.1 - 5.2e-15 55.0 29.5 1e-05 25.7 4.2 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFR04823.1 - 4.7e-10 39.4 13.1 5.4e-07 29.8 4.3 4.7 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR04823.1 - 2.8e-08 33.9 21.5 0.0053 17.5 3.2 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFR04823.1 - 0.031 14.6 4.1 2.2 8.7 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KFR04823.1 - 0.15 12.7 5.9 5.6 7.7 1.8 2.8 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-met PF12874.7 KFR04823.1 - 0.38 11.2 9.5 2.7 8.5 0.7 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KFR04823.1 - 0.41 11.1 5.8 13 6.3 0.1 2.8 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Adap_comp_sub PF00928.21 KFR04824.1 - 2e-84 283.1 0.9 3.3e-84 282.4 0.6 1.5 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFR04824.1 - 3.2e-05 23.9 0.8 6.5e-05 22.9 0.8 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF5482 PF17579.2 KFR04824.1 - 0.015 15.2 0.0 0.18 11.7 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5482) muHD PF10291.9 KFR04824.1 - 0.023 14.2 0.1 0.062 12.7 0.0 1.7 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain AAA_10 PF12846.7 KFR04825.1 - 0.0032 16.5 2.7 0.0035 16.3 2.7 1.0 1 0 0 1 1 1 1 AAA-like domain UPF0172 PF03665.13 KFR04825.1 - 0.026 14.6 1.0 0.032 14.3 1.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF5384 PF17358.2 KFR04825.1 - 0.53 10.3 12.1 0.59 10.2 12.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5384) DUF1754 PF08555.10 KFR04825.1 - 0.92 10.3 20.3 0.94 10.3 16.4 2.5 2 1 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) DUF3395 PF11875.8 KFR04825.1 - 3.7 7.4 11.9 0.25 11.2 3.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3395) DUF1764 PF08576.10 KFR04825.1 - 8.5 7.3 10.0 11 7.0 10.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) EF-hand_7 PF13499.6 KFR04826.1 - 1.8e-15 57.1 3.3 3.4e-12 46.6 0.6 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFR04826.1 - 1.2e-11 43.2 6.1 8.2e-05 21.9 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KFR04826.1 - 1e-10 40.7 5.5 0.0015 18.3 0.3 3.8 3 1 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 KFR04826.1 - 5.5e-05 22.9 5.8 0.0013 18.6 0.3 2.9 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KFR04826.1 - 0.0027 17.1 0.1 0.0027 17.1 0.1 3.2 4 0 0 4 4 4 1 EF hand SPARC_Ca_bdg PF10591.9 KFR04826.1 - 0.048 14.0 0.5 0.097 13.0 0.5 1.6 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_13 PF17958.1 KFR04826.1 - 0.063 13.1 0.0 13 5.6 0.0 3.1 2 1 0 2 2 2 0 EF-hand domain Ras PF00071.22 KFR04827.1 - 4.8e-30 104.3 0.2 5.7e-30 104.1 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR04827.1 - 5.4e-05 23.4 0.2 0.00014 22.1 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF3963 PF13124.6 KFR04827.1 - 0.041 13.9 0.4 0.073 13.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) Tropomyosin PF00261.20 KFR04828.1 - 1.1e-102 342.4 85.1 1.9e-97 325.3 61.4 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 KFR04828.1 - 1e-39 135.9 71.9 1.1e-35 122.9 40.1 3.1 1 1 0 2 2 2 2 Tropomyosin like Laminin_II PF06009.12 KFR04828.1 - 6.1e-08 32.8 32.4 0.00026 21.0 7.4 3.3 1 1 2 3 3 3 2 Laminin Domain II CLZ PF16526.5 KFR04828.1 - 2.9e-07 30.7 46.9 4.3e-06 27.0 8.7 5.1 2 2 3 5 5 5 3 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Laminin_I PF06008.14 KFR04828.1 - 2.7e-05 24.0 49.8 0.00011 22.0 13.7 3.2 1 1 2 3 3 3 2 Laminin Domain I ATG16 PF08614.11 KFR04828.1 - 0.00029 21.1 56.8 0.0041 17.4 18.6 3.5 1 1 1 2 2 1 1 Autophagy protein 16 (ATG16) ERM PF00769.19 KFR04828.1 - 0.0021 17.9 68.2 0.28 11.0 23.3 2.7 1 1 1 2 2 2 2 Ezrin/radixin/moesin family BST2 PF16716.5 KFR04828.1 - 0.0022 18.5 7.7 0.0022 18.5 7.7 5.0 1 1 4 5 5 5 1 Bone marrow stromal antigen 2 TMF_DNA_bd PF12329.8 KFR04828.1 - 0.005 16.8 14.2 0.005 16.8 14.2 6.4 1 1 4 6 6 5 3 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 KFR04828.1 - 0.0053 16.8 65.2 0.016 15.2 30.9 2.5 2 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 KFR04828.1 - 0.0072 15.7 8.3 0.0072 15.7 8.3 3.7 1 1 3 4 4 4 1 Protein of unknown function (DUF3450) AAA_13 PF13166.6 KFR04828.1 - 0.0078 14.9 46.5 0.21 10.2 26.2 2.0 1 1 1 2 2 2 2 AAA domain DHR10 PF18595.1 KFR04828.1 - 0.015 15.4 28.3 0.015 15.4 28.3 3.4 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain XhlA PF10779.9 KFR04828.1 - 0.019 15.2 2.6 0.019 15.2 2.6 6.5 1 1 6 7 7 7 0 Haemolysin XhlA Lebercilin PF15619.6 KFR04828.1 - 0.027 14.1 58.9 0.12 12.0 16.8 3.3 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease MscS_porin PF12795.7 KFR04828.1 - 0.029 13.9 43.2 0.092 12.3 20.0 3.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain COG2 PF06148.11 KFR04828.1 - 0.048 13.8 1.4 0.048 13.8 1.4 4.1 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 KFR04828.1 - 0.073 13.1 31.4 0.079 13.0 4.1 3.7 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) SNARE PF05739.19 KFR04828.1 - 0.091 12.8 5.9 2.3 8.3 0.1 3.9 3 1 1 4 4 4 0 SNARE domain HrpB7 PF09486.10 KFR04828.1 - 0.094 13.1 50.1 0.046 14.1 13.3 4.4 1 1 3 4 4 4 0 Bacterial type III secretion protein (HrpB7) DUF745 PF05335.13 KFR04828.1 - 0.17 11.6 46.4 0.86 9.3 7.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF745) Spc7 PF08317.11 KFR04828.1 - 0.22 10.4 62.6 0.12 11.2 26.9 2.7 1 1 2 3 3 3 0 Spc7 kinetochore protein SlyX PF04102.12 KFR04828.1 - 0.23 12.1 45.1 0.21 12.2 1.2 5.6 1 1 4 5 5 5 0 SlyX FPP PF05911.11 KFR04828.1 - 0.27 9.4 60.1 0.046 11.9 30.6 2.9 1 1 2 3 3 3 0 Filament-like plant protein, long coiled-coil Golgin_A5 PF09787.9 KFR04828.1 - 0.3 10.5 53.5 4 6.8 21.5 2.7 1 1 2 3 3 3 0 Golgin subfamily A member 5 EzrA PF06160.12 KFR04828.1 - 0.31 9.2 54.6 0.24 9.5 6.4 3.2 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA Exonuc_VII_L PF02601.15 KFR04828.1 - 0.38 10.3 32.9 3.7 7.0 16.8 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF3584 PF12128.8 KFR04828.1 - 0.47 7.9 54.4 0.41 8.1 23.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) NPV_P10 PF05531.12 KFR04828.1 - 0.48 10.9 19.3 3.2 8.3 2.3 4.5 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 KFR04828.1 - 0.8 10.2 39.0 0.54 10.8 6.5 4.4 1 1 3 4 4 4 0 Protein of unknown function DUF16 ADIP PF11559.8 KFR04828.1 - 0.87 9.7 48.3 1.5 8.9 6.9 4.2 1 1 4 5 5 5 0 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 KFR04828.1 - 0.92 9.9 51.1 11 6.4 25.0 3.1 1 1 1 2 2 2 0 Fez1 Fib_alpha PF08702.10 KFR04828.1 - 1.3 9.2 30.8 0.25 11.5 6.5 3.3 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family FH2 PF02181.23 KFR04828.1 - 1.8 7.6 38.7 0.18 10.9 8.8 3.2 1 1 2 3 3 3 0 Formin Homology 2 Domain GAS PF13851.6 KFR04828.1 - 2 7.7 63.5 0.52 9.6 23.3 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Flagellin_N PF00669.20 KFR04828.1 - 2.1 8.5 17.7 2 8.5 5.6 3.8 1 1 3 4 4 4 0 Bacterial flagellin N-terminal helical region FUSC PF04632.12 KFR04828.1 - 2.6 6.5 16.5 4.2 5.8 9.6 2.1 1 1 0 2 2 2 0 Fusaric acid resistance protein family Uds1 PF15456.6 KFR04828.1 - 2.7 8.2 48.0 0.89 9.7 15.2 5.2 1 1 4 5 5 5 0 Up-regulated During Septation DUF1794 PF08768.11 KFR04828.1 - 2.8 7.9 5.1 28 4.6 0.2 3.0 2 2 1 3 3 3 0 Domain of unknown function (DUF1794) HemX PF04375.14 KFR04828.1 - 3.1 7.0 35.6 1.1 8.4 13.4 3.2 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase LOH1CR12 PF10158.9 KFR04828.1 - 4.8 7.2 14.3 0.86 9.6 2.2 3.3 1 1 1 3 3 3 0 Tumour suppressor protein T3SSipB PF16535.5 KFR04828.1 - 5.2 7.5 48.1 1.2 9.6 14.2 4.5 1 1 3 4 4 4 0 Type III cell invasion protein SipB DUF2721 PF11026.8 KFR04828.1 - 7.1 6.5 6.3 9.2 6.2 0.2 3.1 2 1 2 4 4 2 0 Protein of unknown function (DUF2721) TTKRSYEDQ PF10212.9 KFR04828.1 - 7.5 5.4 35.5 2.1 7.3 10.8 2.4 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein ApoO PF09769.9 KFR04828.1 - 7.9 6.5 9.2 8.8 6.3 0.4 3.8 1 1 1 3 3 3 0 Apolipoprotein O SH3BP5 PF05276.14 KFR04828.1 - 8.2 6.2 44.6 1.1 9.0 8.9 4.0 1 1 2 3 3 3 0 SH3 domain-binding protein 5 (SH3BP5) Yae1_N PF09811.9 KFR04829.1 - 4.5e-09 35.8 23.4 0.22 11.2 23.4 3.0 1 1 0 1 1 1 1 Essential protein Yae1, N terminal Y_phosphatase PF00102.27 KFR04830.1 - 7.4e-168 555.9 0.3 1.5e-84 283.2 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 KFR04830.1 - 1.7e-113 371.1 23.6 6e-17 61.8 0.0 9.2 9 0 0 9 9 9 8 Fibronectin type III domain I-set PF07679.16 KFR04830.1 - 5.1e-41 138.6 0.0 5.6e-16 58.4 0.0 4.6 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR04830.1 - 1.9e-37 127.7 4.2 1.7e-11 44.5 0.0 6.1 6 0 0 6 6 6 3 Immunoglobulin domain Ig_2 PF13895.6 KFR04830.1 - 2.6e-24 85.3 0.1 2.8e-08 34.0 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 KFR04830.1 - 8.4e-18 64.3 0.0 5.9e-05 23.2 0.0 5.1 5 0 0 5 5 5 3 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFR04830.1 - 7.9e-15 55.2 16.8 0.21 12.2 0.0 9.6 7 3 0 8 8 7 4 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.5 KFR04830.1 - 8.7e-14 51.4 0.0 0.0016 18.6 0.0 7.8 8 0 0 8 8 8 2 Fibronectin type III domain Interfer-bind PF09294.10 KFR04830.1 - 5.1e-11 42.8 0.0 0.36 11.2 0.0 6.3 6 0 0 6 6 5 2 Interferon-alpha/beta receptor, fibronectin type III DSPc PF00782.20 KFR04830.1 - 6.7e-09 35.7 0.0 0.0045 16.8 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFR04830.1 - 6.4e-07 29.6 0.0 0.039 13.9 0.0 2.3 2 0 0 2 2 2 2 Tyrosine phosphatase family V-set PF07686.17 KFR04830.1 - 8.6e-07 29.1 0.5 2.2 8.5 0.0 6.3 5 1 1 6 6 6 2 Immunoglobulin V-set domain PTPlike_phytase PF14566.6 KFR04830.1 - 1.4e-05 25.3 0.0 0.0098 16.0 0.0 3.0 2 0 0 2 2 2 1 Inositol hexakisphosphate C2-set_2 PF08205.12 KFR04830.1 - 1.9e-05 24.6 0.4 1 9.4 0.0 4.0 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFR04830.1 - 0.00029 21.2 0.0 0.6 10.5 0.0 3.8 4 0 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain DUF2369 PF10179.9 KFR04830.1 - 0.0038 17.6 0.0 77 3.8 0.0 5.8 7 0 0 7 7 6 0 Uncharacterised conserved protein (DUF2369) fn3_4 PF16794.5 KFR04830.1 - 0.011 15.7 3.1 7.8 6.5 0.0 5.7 7 0 0 7 7 7 0 Fibronectin-III type domain DUF4998 PF16389.5 KFR04830.1 - 0.054 13.1 0.1 1.6 8.3 0.0 3.0 3 1 0 3 3 2 0 Domain of unknown function Ig_C17orf99 PF17736.1 KFR04830.1 - 0.13 12.4 0.0 16 5.6 0.0 3.9 3 1 0 3 3 3 0 C17orf99 Ig domain Glyco_hydro_36C PF16874.5 KFR04830.1 - 0.16 12.5 0.0 1.8e+02 2.7 0.0 4.6 4 0 0 4 4 4 0 Glycosyl hydrolase family 36 C-terminal domain JmjC PF02373.22 KFR04831.1 - 2.8e-44 150.2 0.3 8e-44 148.7 0.0 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 KFR04831.1 - 5.4e-36 123.1 9.0 5.4e-36 123.1 9.0 2.1 2 0 0 2 2 2 1 PHD-zinc-finger like domain Tudor_2 PF18104.1 KFR04831.1 - 8.2e-32 108.6 1.4 1.4e-16 59.8 0.4 2.6 2 0 0 2 2 2 2 Jumonji domain-containing protein 2A Tudor domain zf-HC5HC2H PF13771.6 KFR04831.1 - 3.8e-18 65.5 5.5 3.8e-18 65.5 5.5 3.2 2 1 1 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KFR04831.1 - 1.7e-13 49.9 15.7 2.2e-13 49.5 6.9 2.9 2 0 0 2 2 2 1 PHD-finger JmjN PF02375.17 KFR04831.1 - 2.8e-13 49.6 0.0 8.7e-13 48.0 0.0 1.9 1 0 0 1 1 1 1 jmjN domain LBR_tudor PF09465.10 KFR04831.1 - 7.1e-06 25.7 0.7 0.13 12.1 0.0 2.6 2 0 0 2 2 2 2 Lamin-B receptor of TUDOR domain PHD PF00628.29 KFR04831.1 - 9.4e-06 25.4 22.2 4.9e-05 23.1 2.7 3.2 3 0 0 3 3 3 2 PHD-finger Tudor_3 PF18115.1 KFR04831.1 - 0.0088 15.9 0.5 1.1 9.1 0.2 2.5 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 KFR04831.1 - 0.021 14.8 0.1 0.19 11.7 0.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4537) Rad9_Rad53_bind PF08605.10 KFR04831.1 - 0.029 14.5 0.1 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 Fungal Rad9-like Rad53-binding SLX9 PF15341.6 KFR04831.1 - 0.14 12.5 4.8 0.39 11.1 4.8 1.6 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 TTD PF12148.8 KFR04832.1 - 4.6e-67 224.7 0.7 8e-67 223.9 0.7 1.4 1 0 0 1 1 1 1 Tandem tudor domain within UHRF1 SAD_SRA PF02182.17 KFR04832.1 - 1e-56 191.0 0.1 2.5e-56 189.7 0.1 1.7 1 0 0 1 1 1 1 SAD/SRA domain PHD PF00628.29 KFR04832.1 - 3.5e-12 46.0 7.6 3.5e-12 46.0 7.6 3.6 3 1 1 4 4 2 1 PHD-finger zf-C3HC4_2 PF13923.6 KFR04832.1 - 0.00045 20.0 12.1 0.00045 20.0 12.1 3.1 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFR04832.1 - 0.00086 19.1 8.7 0.00086 19.1 8.7 3.5 4 1 0 4 4 4 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFR04832.1 - 0.0011 18.7 12.3 0.0011 18.7 12.3 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.6 KFR04832.1 - 0.0011 18.4 0.5 0.0011 18.4 0.5 2.9 3 0 0 3 3 2 1 PHD-finger zf-RING_10 PF16685.5 KFR04832.1 - 0.0091 16.1 7.4 0.0091 16.1 7.4 3.0 2 1 0 2 2 1 1 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 KFR04832.1 - 0.012 15.6 9.1 0.012 15.6 9.1 2.7 2 1 0 2 2 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 KFR04832.1 - 0.014 15.7 12.2 0.014 15.7 12.2 3.3 2 1 1 3 3 3 0 Ring finger domain Agenet PF05641.12 KFR04832.1 - 0.026 15.0 0.1 10 6.7 0.1 2.9 2 1 0 2 2 2 0 Agenet domain Tudor-knot PF11717.8 KFR04832.1 - 0.03 14.2 0.0 2 8.4 0.0 2.5 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain HicB-like_2 PF15970.5 KFR04832.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system DUF3592 PF12158.8 KFR04832.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) Perilipin PF03036.16 KFR04833.1 - 3.8e-146 487.1 20.1 4.3e-146 486.9 20.1 1.0 1 0 0 1 1 1 1 Perilipin family MAP65_ASE1 PF03999.12 KFR04833.1 - 0.008 14.9 5.8 0.35 9.5 3.8 2.9 1 1 1 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Picorna_P3A PF06363.11 KFR04833.1 - 0.021 14.7 1.1 0.35 10.8 0.8 2.5 2 1 0 2 2 2 0 Picornaviridae P3A protein ISG65-75 PF11727.8 KFR04833.1 - 0.047 12.9 4.3 3.6 6.7 0.2 3.2 3 0 0 3 3 3 0 Invariant surface glycoprotein DUF883 PF05957.13 KFR04833.1 - 0.12 13.0 9.5 0.27 11.8 2.1 3.5 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) CHDCT2 PF08074.11 KFR04833.1 - 0.14 12.3 5.8 0.38 10.9 1.0 3.3 1 1 2 4 4 4 0 CHDCT2 (NUC038) domain tRNA_bind_3 PF17176.4 KFR04833.1 - 0.23 11.8 3.5 1.2 9.4 0.6 3.0 3 0 0 3 3 3 0 tRNA-binding domain PHA_gran_rgn PF09650.10 KFR04833.1 - 0.35 11.2 3.4 0.46 10.8 0.2 2.8 3 1 1 4 4 4 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) Baculo_PEP_C PF04513.12 KFR04833.1 - 2.5 8.1 9.7 4.2 7.4 0.3 4.0 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus TRIF-NTD PF17798.1 KFR04834.1 - 7e-55 185.4 2.4 1.1e-54 184.7 2.4 1.3 1 0 0 1 1 1 1 TRIF N-terminal domain TIR_2 PF13676.6 KFR04834.1 - 0.00015 22.3 0.0 0.00028 21.5 0.0 1.4 1 0 0 1 1 1 1 TIR domain TIR-like PF10137.9 KFR04834.1 - 0.093 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Ank_2 PF12796.7 KFR04835.1 - 1.2e-51 173.2 0.3 1.4e-17 64.0 0.1 5.7 2 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 KFR04835.1 - 6.5e-40 133.9 12.4 1.1e-05 25.7 0.0 8.7 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.6 KFR04835.1 - 7.4e-40 134.8 2.6 1.9e-08 34.6 0.1 8.2 4 3 4 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFR04835.1 - 2.8e-39 128.6 5.5 3.1e-05 24.0 0.0 10.3 10 1 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 KFR04835.1 - 7.9e-37 124.9 9.0 2.7e-07 30.7 0.2 8.5 5 1 4 9 9 9 8 Ankyrin repeats (many copies) TPR_12 PF13424.6 KFR04835.1 - 0.0011 19.2 0.1 0.067 13.5 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFR04835.1 - 0.059 13.5 3.9 0.21 11.8 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFR04835.1 - 0.11 12.4 2.5 0.51 10.3 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DPPIV_N PF00930.21 KFR04836.1 - 3.7e-102 341.7 0.0 4.9e-102 341.3 0.0 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KFR04836.1 - 7.5e-55 185.7 0.0 1.4e-54 184.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KFR04836.1 - 1.2e-06 28.3 0.1 2.2e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KFR04836.1 - 0.0085 16.7 0.0 0.019 15.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KFR04836.1 - 0.012 15.2 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Putative esterase DLH PF01738.18 KFR04836.1 - 0.04 13.5 0.0 0.1 12.1 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KFR04836.1 - 0.049 13.3 0.9 0.75 9.4 0.1 2.9 3 0 0 3 3 3 0 alpha/beta hydrolase fold UPF0556 PF10572.9 KFR04837.1 - 1.1e-67 226.3 0.2 1.4e-67 226.0 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0556 DUF758 PF05527.11 KFR04838.1 - 2e-77 259.2 4.3 2.3e-77 259.1 4.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) RPAP3_C PF13877.6 KFR04838.1 - 0.012 16.1 1.1 0.029 14.9 0.3 1.9 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 HD_3 PF13023.6 KFR04838.1 - 0.041 13.8 0.4 0.07 13.0 0.4 1.4 1 0 0 1 1 1 0 HD domain DUF459 PF04311.13 KFR04838.1 - 0.11 11.5 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF459) Sema PF01403.19 KFR04839.1 - 1.1e-126 423.1 0.0 1.5e-126 422.7 0.0 1.1 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 KFR04839.1 - 4.2e-05 24.0 4.1 4.2e-05 24.0 4.1 1.9 2 0 0 2 2 2 1 Plexin repeat LapA_dom PF06305.11 KFR04839.1 - 0.12 12.2 0.1 0.26 11.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Squash PF00299.18 KFR04839.1 - 6.8 6.8 6.6 1.9 8.6 2.6 2.2 2 0 0 2 2 2 0 Squash family serine protease inhibitor Perilipin PF03036.16 KFR04840.1 - 1.1e-162 541.6 24.8 1.5e-161 537.8 24.8 1.9 1 1 0 1 1 1 1 Perilipin family UPF0444 PF15475.6 KFR04840.1 - 0.013 15.8 8.3 0.013 15.8 8.3 2.1 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 VPS13_C PF16909.5 KFR04840.1 - 0.027 14.3 2.7 0.23 11.2 0.2 3.1 2 1 1 3 3 3 0 Vacuolar-sorting-associated 13 protein C-terminal ApoLp-III PF07464.11 KFR04840.1 - 0.065 13.3 13.3 1.1 9.4 0.2 4.2 3 3 1 4 4 4 0 Apolipophorin-III precursor (apoLp-III) DUF2505 PF10698.9 KFR04840.1 - 0.12 12.5 3.8 0.061 13.4 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2505) Spc7 PF08317.11 KFR04840.1 - 0.25 10.2 10.6 0.37 9.6 3.0 2.7 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF948 PF06103.11 KFR04840.1 - 0.33 11.2 8.9 7 7.0 0.0 4.7 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 KFR04840.1 - 0.62 10.1 10.9 1.7 8.7 0.2 3.6 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) THOC7 PF05615.13 KFR04840.1 - 0.65 10.3 3.3 3.6 7.9 0.0 2.8 2 1 0 2 2 2 0 Tho complex subunit 7 Arm-DNA-bind_3 PF13356.6 KFR04840.1 - 1.7 9.1 6.2 11 6.5 0.1 2.7 2 1 0 2 2 2 0 Arm DNA-binding domain DUF1993 PF09351.10 KFR04840.1 - 3.5 7.8 8.5 13 5.9 0.3 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF1993) COG2 PF06148.11 KFR04840.1 - 7.7 6.6 7.4 3.2 7.8 0.1 3.6 3 2 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 LEDGF PF11467.8 KFR04841.1 - 5.5e-28 97.0 1.4 1.5e-27 95.6 1.4 1.7 1 0 0 1 1 1 1 Lens epithelium-derived growth factor (LEDGF) PWWP PF00855.17 KFR04841.1 - 0.0033 17.8 0.0 0.0033 17.8 0.0 3.0 3 0 0 3 3 3 1 PWWP domain CAF1-p150_C2 PF15539.6 KFR04842.1 - 2.2e-120 401.5 1.8 7.2e-120 399.8 1.8 1.9 1 0 0 1 1 1 1 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term CAF-1_p150 PF11600.8 KFR04842.1 - 7.6e-66 220.8 70.0 2.2e-65 219.4 70.0 1.8 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal CAF1-p150_N PF15557.6 KFR04842.1 - 9.4e-38 130.4 9.2 9.4e-38 130.4 9.2 2.6 1 1 2 3 3 3 1 CAF1 complex subunit p150, region binding to PCNA CAF1A PF12253.8 KFR04842.1 - 7.9e-26 90.0 9.7 7.9e-26 90.0 9.7 5.7 5 1 0 5 5 5 1 Chromatin assembly factor 1 subunit A SPRY PF00622.28 KFR04843.1 - 1.4e-10 41.4 0.1 2.6e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 SPRY domain fn3 PF00041.21 KFR04843.1 - 1.8e-07 31.4 0.0 1.1e-06 28.9 0.0 2.2 2 0 0 2 2 2 1 Fibronectin type III domain AAA_13 PF13166.6 KFR04843.1 - 0.049 12.3 1.5 0.062 11.9 1.5 1.1 1 0 0 1 1 1 0 AAA domain fn3_4 PF16794.5 KFR04843.1 - 0.067 13.1 0.0 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 Fibronectin-III type domain OmpH PF03938.14 KFR04843.1 - 1.3 9.4 7.6 2.2 8.6 7.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) WXG100 PF06013.12 KFR04843.1 - 2.7 8.3 5.7 3.1 8.1 0.7 2.4 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DUF572 PF04502.13 KFR04844.1 - 1.5e-95 320.6 19.6 1.7e-95 320.5 19.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) RRM_1 PF00076.22 KFR04845.1 - 3.7e-53 177.2 0.1 5.7e-19 67.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M PF11532.8 KFR04845.1 - 4.9e-18 65.0 8.7 1e-17 64.0 8.7 1.6 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein M Collagen_mid PF15984.5 KFR04845.1 - 1.3e-06 28.3 0.3 8.2e-05 22.4 0.2 2.5 1 1 1 2 2 2 1 Bacterial collagen, middle region RRM_3 PF08777.11 KFR04845.1 - 3.9e-05 23.6 0.3 0.21 11.7 0.0 2.9 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.8 KFR04845.1 - 7e-05 22.8 0.2 0.0044 17.1 0.1 2.6 2 1 0 2 2 2 1 Limkain b1 RRM_5 PF13893.6 KFR04845.1 - 0.0024 17.5 0.0 0.15 11.6 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFR04845.1 - 0.0087 15.9 0.0 0.21 11.5 0.0 2.3 2 0 0 2 2 2 1 Occluded RNA-recognition motif DUF3932 PF13068.6 KFR04845.1 - 0.045 14.0 0.0 1.6 9.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3932) Tim44 PF04280.15 KFR04846.1 - 2.3e-43 147.8 0.3 7.5e-43 146.1 0.0 1.9 2 0 0 2 2 2 1 Tim44-like domain Kinase-PolyVal PF18762.1 KFR04846.1 - 0.032 14.2 0.2 0.068 13.1 0.2 1.5 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins DUF5089 PF17002.5 KFR04846.1 - 0.14 12.0 17.0 1.3 8.9 15.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5089) DUF3347 PF11827.8 KFR04846.1 - 1.8 8.7 13.8 4.5 7.4 4.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3347) AIM3 PF17096.5 KFR04846.1 - 2.8 8.9 8.0 0.14 13.1 0.7 2.2 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 RecG_N PF17190.4 KFR04846.1 - 4.3 8.1 8.5 8.7 7.1 4.1 3.2 2 1 1 3 3 3 0 RecG N-terminal helical domain PIN_8 PF18476.1 KFR04846.1 - 8.3 6.2 13.4 13 5.5 9.7 2.4 1 1 1 2 2 2 0 PIN like domain Lamprin PF06403.11 KFR04847.1 - 1.7e-05 24.8 13.5 0.004 17.1 5.6 2.0 1 1 1 2 2 2 2 Lamprin Chorion_1 PF01723.16 KFR04847.1 - 0.013 15.5 25.4 1.1e+02 2.7 25.4 2.2 1 1 0 1 1 1 0 Chorion protein Cortexin PF11057.8 KFR04848.1 - 4e-40 135.5 0.1 4.5e-40 135.4 0.1 1.1 1 0 0 1 1 1 1 Cortexin of kidney EGF_CA PF07645.15 KFR04849.1 - 0 1028.1 733.8 6.1e-11 42.3 5.1 49.3 48 1 3 51 51 51 44 Calcium-binding EGF domain cEGF PF12662.7 KFR04849.1 - 1.3e-208 674.0 417.5 3.9e-09 36.3 0.2 50.9 50 0 0 50 50 50 44 Complement Clr-like EGF-like TB PF00683.17 KFR04849.1 - 7.2e-121 393.8 153.5 9.8e-16 57.2 10.0 11.1 9 0 0 9 9 9 9 TB domain EGF PF00008.27 KFR04849.1 - 1.6e-102 335.2 686.4 0.00041 20.6 5.6 50.0 49 0 0 49 49 49 44 EGF-like domain FXa_inhibition PF14670.6 KFR04849.1 - 5.6e-88 288.9 721.2 2e-08 34.3 11.4 48.5 45 3 2 47 47 47 41 Coagulation Factor Xa inhibitory site hEGF PF12661.7 KFR04849.1 - 5.5e-68 223.5 676.7 0.00047 20.7 6.0 53.8 54 0 0 54 54 54 39 Human growth factor-like EGF EGF_3 PF12947.7 KFR04849.1 - 3.9e-47 158.1 605.9 2.7e-09 37.1 5.3 49.1 46 1 1 47 47 47 38 EGF domain Fibrillin_U_N PF18193.1 KFR04849.1 - 5.3e-25 87.2 7.7 5.3e-25 87.2 7.7 11.3 12 0 0 12 12 12 1 Fibrillin 1 unique N-terminal domain Plasmod_Pvs28 PF06247.11 KFR04849.1 - 0.038 14.3 498.6 0.0092 16.3 5.2 44.4 41 4 4 45 45 45 0 Pvs28 EGF domain fn3 PF00041.21 KFR04850.1 - 2.3e-07 31.0 0.5 1.8e-06 28.2 0.1 2.2 2 1 0 2 2 2 1 Fibronectin type III domain IL6Ra-bind PF09240.10 KFR04850.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Interleukin-6 receptor alpha chain, binding SIR2 PF02146.17 KFR04851.1 - 4.5e-26 91.8 0.0 1e-17 64.7 0.0 2.2 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 KFR04851.1 - 0.0011 18.7 0.0 0.07 12.9 0.0 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain bZIP_1 PF00170.21 KFR04852.1 - 1.5e-12 47.4 15.5 3e-12 46.4 15.2 1.6 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 KFR04852.1 - 1.4e-08 34.6 10.3 1.4e-08 34.6 10.3 2.3 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.17 KFR04852.1 - 4.2e-05 24.0 10.2 8e-05 23.1 10.2 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor OppC_N PF12911.7 KFR04852.1 - 0.056 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C KASH_CCD PF14662.6 KFR04852.1 - 0.062 13.1 10.7 0.089 12.6 10.7 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF2207 PF09972.9 KFR04852.1 - 0.064 12.0 0.1 0.086 11.6 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1664 PF07889.12 KFR04852.1 - 0.077 13.0 2.0 0.12 12.5 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 KFR04852.1 - 0.086 12.2 1.3 0.12 11.7 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ZapB PF06005.12 KFR04852.1 - 0.12 12.8 9.2 0.04 14.4 6.1 1.8 1 1 1 2 2 2 0 Cell division protein ZapB BORG_CEP PF14957.6 KFR04852.1 - 0.13 13.4 3.3 0.1 13.8 0.8 2.0 2 0 0 2 2 2 0 Cdc42 effector ADIP PF11559.8 KFR04852.1 - 0.14 12.3 12.9 0.22 11.6 12.9 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding MCU PF04678.13 KFR04852.1 - 0.22 11.6 1.7 0.34 11.0 1.7 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter RNA_polI_A14 PF08203.11 KFR04852.1 - 0.27 12.0 3.4 0.52 11.1 3.4 1.5 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 DUF724 PF05266.14 KFR04852.1 - 0.34 10.7 5.7 0.52 10.1 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) SOGA PF11365.8 KFR04852.1 - 0.82 10.8 10.0 0.73 11.0 8.1 1.8 1 1 1 2 2 2 0 Protein SOGA Pkinase PF00069.25 KFR04853.1 - 1e-60 205.3 0.0 1.5e-60 204.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR04853.1 - 2.8e-34 118.6 0.0 1.2e-32 113.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFR04853.1 - 8.7e-05 21.5 0.0 0.00012 20.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFR04853.1 - 0.0038 16.2 0.0 0.0053 15.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFR04853.1 - 0.0054 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFR04853.1 - 0.014 15.4 0.0 0.045 13.7 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFR04853.1 - 0.029 13.4 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 KFR04853.1 - 0.2 11.0 0.5 0.32 10.3 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PINIT PF14324.6 KFR04854.1 - 1.7e-31 109.5 0.2 2.9e-31 108.8 0.2 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KFR04854.1 - 6.9e-22 76.9 5.7 1.8e-21 75.6 5.7 1.8 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.27 KFR04854.1 - 2.9e-05 23.7 0.1 0.00017 21.3 0.0 2.2 2 0 0 2 2 2 1 SAP domain zf-Nse PF11789.8 KFR04854.1 - 4.9e-05 23.0 1.7 4.9e-05 23.0 1.7 1.8 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Ribosomal_60s PF00428.19 KFR04854.1 - 0.055 14.1 2.1 0.33 11.5 2.3 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein GTP_EFTU PF00009.27 KFR04855.1 - 4.8e-65 218.7 0.0 6.6e-65 218.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KFR04855.1 - 1.9e-34 118.0 0.0 8.1e-34 116.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KFR04855.1 - 5.5e-23 80.8 0.0 1.3e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KFR04855.1 - 1.9e-13 50.3 0.0 4.9e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KFR04855.1 - 1.2e-12 48.0 0.2 7.5e-12 45.5 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFR04855.1 - 1.7e-05 24.9 0.1 3.3e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Pkinase PF00069.25 KFR04856.1 - 4e-76 255.9 0.0 4.5e-76 255.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR04856.1 - 3.6e-37 128.1 0.0 4.2e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFR04856.1 - 1.7e-06 27.6 0.2 3.2e-06 26.7 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFR04856.1 - 9.2e-06 25.4 0.1 1.3e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KFR04856.1 - 0.04 13.5 0.1 0.07 12.7 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF3847 PF12958.7 KFR04856.1 - 0.044 13.9 0.1 0.14 12.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) FTA2 PF13095.6 KFR04856.1 - 0.064 12.9 0.1 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Glycos_trans_3N PF02885.17 KFR04856.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain APH PF01636.23 KFR04856.1 - 0.17 11.8 0.1 0.39 10.6 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family AAA_18 PF13238.6 KFR04857.1 - 4.5e-07 30.5 0.0 7.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFR04857.1 - 0.044 13.9 0.0 0.15 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KFR04857.1 - 0.13 12.3 0.0 1.1 9.3 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase BNIP2 PF12496.8 KFR04858.1 - 6.2e-42 143.2 0.3 1.1e-41 142.5 0.3 1.4 1 0 0 1 1 1 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CRAL_TRIO_2 PF13716.6 KFR04858.1 - 6.1e-31 107.4 0.2 8.1e-31 107.0 0.2 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KFR04858.1 - 8.6e-08 32.1 0.2 1.2e-07 31.5 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain TGF_beta PF00019.20 KFR04859.1 - 4.7e-12 46.8 0.7 7.8e-12 46.1 0.7 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain Dus PF01207.17 KFR04860.1 - 5e-57 193.3 0.0 7e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 KFR04860.1 - 1.2e-06 28.1 12.7 1.5e-06 27.9 3.6 3.6 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFR04860.1 - 0.0029 17.6 9.0 0.038 14.0 0.7 2.9 2 0 0 2 2 2 2 Zinc finger domain FMN_dh PF01070.18 KFR04860.1 - 0.0063 15.6 0.0 0.0095 15.0 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase zf-CCCH PF00642.24 KFR04860.1 - 0.01 15.7 15.1 0.11 12.5 1.0 3.4 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PEP_mutase PF13714.6 KFR04860.1 - 0.025 14.0 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase zf-CCCH_2 PF14608.6 KFR04860.1 - 1.1 9.8 8.1 1.7 9.2 1.2 3.1 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger PRR22 PF15776.5 KFR04861.1 - 4.6e-10 39.4 9.3 8.7e-08 31.9 4.4 2.1 1 1 1 2 2 2 2 Proline-rich protein family 22 La PF05383.17 KFR04862.1 - 1.2e-20 73.3 0.9 1.8e-20 72.7 0.9 1.3 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KFR04862.1 - 0.0054 16.5 0.0 1.8 8.5 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNR_N PF08343.10 KFR04862.1 - 0.096 12.7 0.1 0.26 11.3 0.1 1.7 2 0 0 2 2 2 0 Ribonucleotide reductase N-terminal RFX1_trans_act PF04589.13 KFR04863.1 - 1e-59 201.3 22.0 1e-59 201.3 22.0 2.7 3 0 0 3 3 3 1 RFX1 transcription activation region RFX_DNA_binding PF02257.15 KFR04863.1 - 1.2e-33 115.6 0.1 3.6e-33 114.0 0.1 1.9 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 KFR04863.1 - 0.056 13.9 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Poxvirus D5 protein-like DUF2258 PF10015.9 KFR04863.1 - 0.13 12.4 0.2 0.33 11.1 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) AMP-binding PF00501.28 KFR04864.1 - 5.7e-88 295.3 0.0 6.9e-88 295.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme LRR_9 PF14580.6 KFR04865.1 - 1.5e-16 60.4 1.4 2.1e-16 59.9 1.4 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KFR04865.1 - 1.6e-14 53.7 17.9 2.9e-08 33.9 3.3 3.7 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFR04865.1 - 4.2e-08 32.8 20.4 5.2e-06 26.1 6.7 3.3 1 1 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 KFR04865.1 - 1.7e-06 27.6 7.0 0.015 15.3 0.2 3.9 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 KFR04865.1 - 0.00026 21.1 9.2 0.97 10.2 0.3 4.6 4 0 0 4 4 4 2 Leucine Rich Repeat SDA1 PF05285.12 KFR04865.1 - 0.45 9.9 30.7 0.58 9.5 30.7 1.3 1 0 0 1 1 1 0 SDA1 zf-H2C2_5 PF13909.6 KFR04866.1 - 6e-05 22.7 0.7 9.4e-05 22.1 0.7 1.3 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf_C2H2_ZHX PF18387.1 KFR04866.1 - 0.07 12.8 0.2 0.14 11.8 0.1 1.5 1 1 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 KFR04866.1 - 0.081 13.4 0.2 0.14 12.7 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type Myosin_head PF00063.21 KFR04867.1 - 2e-253 842.6 4.4 2.4e-253 842.3 4.4 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KFR04867.1 - 5.6e-50 169.6 0.3 1.3e-49 168.4 0.3 1.7 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_9 PF14604.6 KFR04867.1 - 2.2e-14 53.0 0.2 8.5e-14 51.2 0.1 2.2 2 0 0 2 2 1 1 Variant SH3 domain SH3_1 PF00018.28 KFR04867.1 - 4e-13 48.8 0.4 1.6e-12 46.8 0.2 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFR04867.1 - 5.2e-11 42.1 0.1 1.1e-10 41.0 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain AAA_16 PF13191.6 KFR04867.1 - 0.015 15.7 0.0 0.047 14.1 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KFR04867.1 - 0.052 14.1 0.1 0.21 12.1 0.1 2.1 2 0 0 2 2 1 0 ABC transporter Microtub_bd PF16796.5 KFR04867.1 - 0.056 13.4 0.1 0.19 11.7 0.1 1.9 1 0 0 1 1 1 0 Microtubule binding DUF2075 PF09848.9 KFR04867.1 - 0.083 12.1 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KFR04867.1 - 0.085 13.1 0.1 0.29 11.4 0.1 1.9 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 KFR04867.1 - 0.097 12.2 0.4 5.6 6.5 0.1 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain ATP_bind_2 PF03668.15 KFR04867.1 - 0.16 11.2 0.5 0.56 9.4 0.2 2.0 2 0 0 2 2 2 0 P-loop ATPase protein family DUF2158 PF09926.9 KFR04867.1 - 0.17 11.6 0.3 0.41 10.4 0.3 1.6 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) IQ PF00612.27 KFR04867.1 - 0.22 11.4 2.0 0.77 9.7 2.0 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif Pep_M12B_propep PF01562.19 KFR04868.1 - 1.1e-37 129.3 0.1 1.8e-37 128.7 0.1 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_spacer1 PF05986.14 KFR04868.1 - 3.3e-32 110.9 0.0 5.6e-32 110.2 0.0 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 ADAM_CR_2 PF17771.1 KFR04868.1 - 1.5e-17 63.9 9.1 1.5e-17 63.9 9.1 5.5 5 1 0 5 5 5 2 ADAM cysteine-rich domain TSP_1 PF00090.19 KFR04868.1 - 4.1e-17 62.1 84.6 5.4e-07 29.7 8.2 7.6 7 1 0 7 7 7 5 Thrombospondin type 1 domain Reprolysin PF01421.19 KFR04868.1 - 5.5e-11 42.7 1.8 5.5e-11 42.7 1.8 2.5 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease PLAC PF08686.11 KFR04868.1 - 3.4e-09 37.3 11.6 1.6e-08 35.2 11.6 2.3 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Pkinase_Tyr PF07714.17 KFR04869.1 - 4e-92 308.2 1.1 5.4e-92 307.7 1.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR04869.1 - 4.6e-48 163.9 0.3 6.9e-48 163.3 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFR04869.1 - 1.2e-41 140.7 0.1 2.9e-22 78.6 0.1 2.7 2 0 0 2 2 2 2 SH2 domain Haspin_kinase PF12330.8 KFR04869.1 - 0.00028 20.0 1.2 0.00043 19.3 0.3 1.8 2 1 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 KFR04869.1 - 0.0007 19.2 1.8 0.0012 18.5 1.8 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KFR04869.1 - 0.089 12.1 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GrlR PF16518.5 KFR04869.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 T3SS negative regulator,GrlR SEA PF01390.20 KFR04870.1 - 9.8e-137 446.8 13.7 1.1e-24 86.5 0.1 6.1 6 0 0 6 6 6 6 SEA domain SH3_10 PF17902.1 KFR04870.1 - 2.9e-05 24.1 0.0 14 5.8 0.0 4.5 4 0 0 4 4 4 2 SH3 domain Epiglycanin_C PF14654.6 KFR04870.1 - 0.012 15.7 0.1 0.029 14.4 0.1 1.7 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region UPF0560 PF10577.9 KFR04870.1 - 0.018 13.6 1.0 0.029 12.9 1.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Afaf PF15339.6 KFR04870.1 - 0.038 13.7 0.1 0.091 12.5 0.1 1.6 1 0 0 1 1 1 0 Acrosome formation-associated factor DUF2205 PF10224.9 KFR04870.1 - 0.096 12.7 0.0 1.9 8.6 0.0 2.5 2 0 0 2 2 2 0 Short coiled-coil protein Phage_DNA_bind PF02303.17 KFR04870.1 - 0.69 10.2 3.8 84 3.5 0.0 4.6 5 0 0 5 5 5 0 Helix-destabilising protein LapA_dom PF06305.11 KFR04870.1 - 0.81 9.5 3.1 1.7 8.5 3.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain AKAP95 PF04988.12 KFR04875.1 - 2.7e-20 73.2 2.0 2.9e-20 73.1 2.0 1.0 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.7 KFR04875.1 - 0.0017 18.6 0.1 0.0017 18.6 0.1 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Actin_micro PF17003.5 KFR04875.1 - 0.021 14.0 0.2 0.021 14.0 0.2 1.0 1 0 0 1 1 1 0 Putative actin-like family zf-Di19 PF05605.12 KFR04875.1 - 0.021 15.1 0.2 0.024 14.9 0.2 1.1 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KFR04875.1 - 5.9 7.3 8.1 23 5.4 8.1 1.8 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.12 KFR04877.1 - 2.4e-74 249.0 7.5 2.4e-74 249.0 7.5 1.7 2 0 0 2 2 2 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.7 KFR04877.1 - 0.23 11.8 6.6 3 8.2 0.9 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFR04877.1 - 6.2 7.4 7.7 0.68 10.4 0.9 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFR04878.1 - 8.5e-11 41.7 17.3 0.0073 17.1 0.3 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-FCS PF06467.14 KFR04878.1 - 0.0027 17.6 5.6 0.16 11.9 0.0 3.2 4 0 0 4 4 4 2 MYM-type Zinc finger with FCS sequence motif zf-C2H2 PF00096.26 KFR04878.1 - 0.0034 17.7 29.8 0.083 13.4 1.0 5.4 5 1 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KFR04878.1 - 0.013 15.8 3.7 17 5.8 0.0 4.0 4 0 0 4 4 4 0 C2H2 type zinc-finger (2 copies) AnfO_nitrog PF09582.10 KFR04878.1 - 0.11 11.8 0.0 0.45 9.8 0.0 1.9 3 0 0 3 3 3 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) zf-MYST PF17772.1 KFR04878.1 - 0.37 10.4 7.1 2 8.1 0.1 2.9 3 0 0 3 3 3 0 MYST family zinc finger domain zf-BED PF02892.15 KFR04878.1 - 0.47 10.5 11.8 0.94 9.6 0.1 4.2 4 0 0 4 4 4 0 BED zinc finger zf-met PF12874.7 KFR04878.1 - 0.49 10.8 18.1 1.9 9.0 0.7 4.6 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFR04878.1 - 2.1 8.8 9.2 6.3 7.2 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KFR04878.1 - 9.3 6.5 13.5 5.9 7.1 0.1 4.2 4 0 0 4 4 4 0 Zinc ribbon domain zf-C2H2_4 PF13894.6 KFR04879.1 - 4.2e-10 39.6 24.4 0.13 13.2 0.8 5.7 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KFR04879.1 - 2.3e-05 24.6 24.8 0.0021 18.4 0.4 5.6 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 KFR04879.1 - 0.0011 18.6 10.1 0.24 11.1 0.1 4.2 4 0 0 4 4 4 3 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 KFR04879.1 - 0.15 12.4 20.7 2.5 8.5 0.4 5.4 4 2 0 5 5 5 0 C2H2 type zinc-finger (2 copies) FeoC PF09012.10 KFR04879.1 - 0.33 11.0 1.6 0.98 9.5 1.6 1.7 1 0 0 1 1 1 0 FeoC like transcriptional regulator zf-C2H2_jaz PF12171.8 KFR04879.1 - 0.71 10.2 12.0 0.62 10.4 2.4 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-Mss51 PF13824.6 KFR04879.1 - 0.88 9.7 9.8 2.6 8.2 0.9 3.8 1 1 2 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 HNH_5 PF14279.6 KFR04879.1 - 1 9.3 6.1 4.1 7.3 3.1 2.8 2 1 0 2 2 2 0 HNH endonuclease zf-C2H2_7 PF15269.6 KFR04879.1 - 1.5 9.0 18.9 0.69 10.0 0.2 5.3 6 0 0 6 6 6 0 Zinc-finger MmgE_PrpD PF03972.14 KFR04894.1 - 4.1e-126 421.1 0.0 5e-126 420.8 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DJ-1_PfpI PF01965.24 KFR04895.1 - 0.00057 19.7 0.2 0.0019 18.0 0.2 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family CLN5 PF15014.6 KFR04896.1 - 5.7e-169 561.4 5.3 6.3e-169 561.3 5.3 1.0 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 Lipase3_N PF03893.16 KFR04896.1 - 0.066 13.3 0.2 0.19 11.8 0.2 1.9 1 0 0 1 1 1 0 Lipase 3 N-terminal region F-box PF00646.33 KFR04897.1 - 1.5e-08 34.3 2.8 1.7e-08 34.1 0.2 2.6 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KFR04897.1 - 2.6e-08 33.6 1.4 2.6e-08 33.6 1.4 2.4 3 0 0 3 3 3 1 F-box-like DUF4116 PF13475.6 KFR04897.1 - 0.0084 15.8 0.3 0.029 14.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4116) F-box_5 PF18511.1 KFR04897.1 - 0.017 14.7 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 F-box SLAIN PF15301.6 KFR04899.1 - 3.6e-158 527.4 28.4 5.8e-141 470.7 22.8 2.0 1 1 1 2 2 2 2 SLAIN motif-containing family 7tm_1 PF00001.21 KFR04901.1 - 1.4e-39 136.0 10.8 2e-39 135.5 10.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR04901.1 - 1e-09 38.2 12.2 2.4e-09 36.9 12.2 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFR04901.1 - 6.4e-06 26.0 6.7 6.4e-06 26.0 6.7 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFR04901.1 - 0.0016 18.3 3.7 0.0026 17.6 3.6 1.7 1 1 0 1 1 1 1 Olfactory receptor PHO4 PF01384.20 KFR04901.1 - 0.06 12.4 1.3 0.084 11.9 1.3 1.3 1 0 0 1 1 1 0 Phosphate transporter family zf-C3HC4_2 PF13923.6 KFR04902.1 - 2.1e-05 24.2 4.9 0.00011 22.0 4.9 2.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFR04902.1 - 8.7e-05 22.8 6.0 8.7e-05 22.8 6.0 2.5 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFR04902.1 - 0.00032 20.5 4.8 0.00096 19.0 4.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFR04902.1 - 0.00053 20.2 6.0 0.00053 20.2 6.0 3.0 4 0 0 4 4 2 1 RING-H2 zinc finger domain zf-P11 PF03854.14 KFR04902.1 - 0.0012 18.5 3.6 0.0033 17.1 3.6 1.7 1 0 0 1 1 1 1 P-11 zinc finger zf-C3HC4 PF00097.25 KFR04902.1 - 0.013 15.4 6.4 0.013 15.4 6.4 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) ZapB PF06005.12 KFR04902.1 - 0.014 15.9 28.9 0.014 15.8 2.7 4.2 3 1 1 4 4 4 0 Cell division protein ZapB zf-RING_5 PF14634.6 KFR04902.1 - 0.06 13.3 6.2 0.17 11.9 3.9 2.9 2 0 0 2 2 2 0 zinc-RING finger domain TolA_bind_tri PF16331.5 KFR04902.1 - 0.14 12.3 9.8 0.52 10.4 0.4 3.3 2 1 0 2 2 2 0 TolA binding protein trimerisation DivIC PF04977.15 KFR04902.1 - 0.19 11.5 13.1 1.6 8.5 0.5 3.6 3 0 0 3 3 3 0 Septum formation initiator Prok-RING_4 PF14447.6 KFR04902.1 - 0.5 10.3 7.9 2.1 8.3 7.9 2.1 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 CENP-H PF05837.12 KFR04902.1 - 0.72 10.3 22.0 0.51 10.8 7.2 3.7 2 1 1 3 3 3 0 Centromere protein H (CENP-H) TSC22 PF01166.18 KFR04902.1 - 0.84 10.0 15.6 0.62 10.4 2.4 4.2 3 1 1 4 4 4 0 TSC-22/dip/bun family SlyX PF04102.12 KFR04902.1 - 3 8.5 10.6 12 6.5 1.1 3.5 3 0 0 3 3 3 0 SlyX PRKG1_interact PF15898.5 KFR04902.1 - 3.9 8.4 32.7 0.09 13.7 9.5 4.2 3 1 0 3 3 3 0 cGMP-dependent protein kinase interacting domain zf-RING_UBOX PF13445.6 KFR04902.1 - 8.2 6.5 9.1 0.49 10.5 1.9 2.8 3 0 0 3 3 3 0 RING-type zinc-finger bZIP_1 PF00170.21 KFR04902.1 - 8.4 6.6 31.0 0.51 10.5 0.7 4.5 5 0 0 5 5 5 0 bZIP transcription factor DUF1272 PF06906.11 KFR04902.1 - 9 6.5 9.2 0.65 10.1 2.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) RVT_1 PF00078.27 KFR04903.1 - 0.084 12.4 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.22 KFR04906.1 - 2e-11 43.5 0.2 0.0002 21.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 KFR04906.1 - 1.1e-09 38.5 0.3 2.3e-09 37.4 0.3 1.6 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.6 KFR04906.1 - 4.9e-07 29.6 0.0 0.00047 20.1 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 KFR04906.1 - 0.0009 19.1 2.7 0.0017 18.2 2.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFR04906.1 - 0.0056 16.7 1.6 0.01 15.9 1.6 1.5 1 0 0 1 1 1 1 Zinc finger domain RGS-like PF09128.11 KFR04906.1 - 0.052 13.3 0.1 0.052 13.3 0.1 2.5 2 1 1 3 3 3 0 Regulator of G protein signalling-like domain Nup35_RRM PF05172.13 KFR04906.1 - 0.14 12.1 0.1 29 4.7 0.0 3.0 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KFR04906.1 - 0.41 10.7 0.0 0.41 10.7 0.0 3.8 4 1 0 4 4 4 0 RNA binding motif DUF2370 PF10176.9 KFR04907.1 - 2.1e-08 34.1 6.2 1.7e-05 24.6 1.7 2.9 1 1 1 2 2 2 2 Protein of unknown function (DUF2370) Comm PF15957.5 KFR04907.1 - 0.16 12.3 0.8 0.43 10.9 0.8 1.8 1 1 0 1 1 1 0 Commissureless DUF202 PF02656.15 KFR04907.1 - 3.7 8.1 7.4 2.5 8.6 5.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF3446 PF11928.8 KFR04907.1 - 4.2 7.7 11.7 7.9 6.9 11.7 1.5 1 0 0 1 1 1 0 Early growth response N-terminal domain Sprouty PF05210.13 KFR04908.1 - 2.2e-28 98.6 36.7 3.9e-28 97.8 36.7 1.4 1 0 0 1 1 1 1 Sprouty protein (Spry) CCDC24 PF15669.5 KFR04908.1 - 2.1 8.1 4.8 5.8 6.7 4.8 1.7 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Gly_acyl_tr_N PF06021.11 KFR04913.1 - 1.3e-38 133.1 0.0 1.5e-38 133.0 0.0 1.0 1 0 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase PRF PF06875.11 KFR04914.1 - 1.2e-06 28.1 0.0 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Plethodontid receptivity factor PRF CNTF PF01110.17 KFR04914.1 - 6.4e-06 25.7 0.0 1.1e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 Ciliary neurotrophic factor IL11 PF07400.11 KFR04914.1 - 0.095 12.3 0.0 0.55 9.9 0.0 2.0 2 0 0 2 2 2 0 Interleukin 11 Myosin_tail_1 PF01576.19 KFR04916.1 - 3.1e-32 111.4 59.4 3.5e-32 111.3 59.4 1.0 1 0 0 1 1 1 1 Myosin tail Tropomyosin PF00261.20 KFR04916.1 - 6.5e-06 25.7 63.0 0.0024 17.3 29.3 3.5 1 1 2 3 3 3 3 Tropomyosin DUF3958 PF13125.6 KFR04916.1 - 0.006 16.8 11.2 0.006 16.8 11.2 4.4 2 2 2 4 4 4 1 Protein of unknown function (DUF3958) Trimer_CC PF08954.11 KFR04916.1 - 0.027 14.0 0.9 0.027 14.0 0.9 4.2 4 0 0 4 4 4 0 Trimerisation motif Uso1_p115_C PF04871.13 KFR04916.1 - 0.047 14.0 56.7 1.2 9.6 14.3 4.3 1 1 3 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region Tropomyosin_1 PF12718.7 KFR04916.1 - 0.088 13.0 62.1 0.11 12.6 19.9 3.5 1 1 2 3 3 3 0 Tropomyosin like MAD PF05557.13 KFR04916.1 - 0.1 10.9 57.6 0.025 13.0 21.7 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein CALCOCO1 PF07888.11 KFR04916.1 - 0.11 11.3 51.0 0.15 10.9 51.0 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Filament PF00038.21 KFR04916.1 - 0.12 11.9 51.9 1.4 8.4 51.7 2.5 1 1 0 1 1 1 0 Intermediate filament protein ATG16 PF08614.11 KFR04916.1 - 0.18 12.0 63.3 0.17 12.1 20.9 3.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 KFR04916.1 - 0.28 11.2 36.1 0.6 10.1 4.7 4.6 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) PspA_IM30 PF04012.12 KFR04916.1 - 0.55 9.8 58.8 0.82 9.2 35.0 3.3 1 1 2 3 3 3 0 PspA/IM30 family Laminin_I PF06008.14 KFR04916.1 - 0.7 9.6 46.7 1.5 8.4 9.8 2.8 1 1 2 3 3 3 0 Laminin Domain I BRE1 PF08647.11 KFR04916.1 - 0.82 9.8 52.3 0.49 10.5 10.0 4.1 2 1 2 4 4 4 0 BRE1 E3 ubiquitin ligase Lipoprotein_7 PF01540.16 KFR04916.1 - 0.85 8.8 27.4 0.063 12.6 20.3 2.1 1 1 1 2 2 2 0 Adhesin lipoprotein TPR_MLP1_2 PF07926.12 KFR04916.1 - 1.2 9.2 63.7 0.16 12.0 9.7 4.2 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein EzrA PF06160.12 KFR04916.1 - 2.3 6.3 46.9 5.5 5.0 18.4 3.0 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA DUF5635 PF18685.1 KFR04916.1 - 3 7.8 6.3 0.65 10.0 0.5 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5635) Fib_alpha PF08702.10 KFR04916.1 - 3.3 7.9 36.0 0.03 14.5 13.9 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Alanine_zipper PF11839.8 KFR04916.1 - 3.5 8.1 39.6 2.1 8.8 3.9 5.8 4 3 1 5 5 5 0 Alanine-zipper, major outer membrane lipoprotein SOGA PF11365.8 KFR04916.1 - 5.2 8.3 42.0 8.4 7.6 2.3 4.5 2 2 2 4 4 4 0 Protein SOGA DUF745 PF05335.13 KFR04916.1 - 7.1 6.3 48.1 9.3 5.9 11.2 3.8 1 1 2 3 3 3 0 Protein of unknown function (DUF745) LPP PF04728.13 KFR04916.1 - 7.4 7.1 28.6 3.6 8.1 1.7 6.1 6 1 0 6 6 6 0 Lipoprotein leucine-zipper CENP-F_leu_zip PF10473.9 KFR04916.1 - 7.4 6.6 61.1 0.16 12.0 16.6 4.0 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF812 PF05667.11 KFR04916.1 - 7.6 5.3 55.2 2.2 7.1 39.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Myosin_head PF00063.21 KFR04917.1 - 6.8e-272 903.6 2.1 6.8e-272 903.6 2.1 3.6 3 1 1 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KFR04917.1 - 1.8e-141 473.1 266.1 3.9e-141 472.0 266.1 1.5 1 1 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 KFR04917.1 - 4e-13 48.9 3.3 1.2e-12 47.4 3.3 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain DUF4537 PF15057.6 KFR04917.1 - 0.0006 19.8 0.7 0.0042 17.1 0.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4537) IQ PF00612.27 KFR04917.1 - 0.0093 15.7 0.1 0.052 13.4 0.0 2.3 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_22 PF13401.6 KFR04917.1 - 0.1 12.9 0.0 0.1 12.9 0.0 5.1 3 2 1 4 4 4 0 AAA domain AAA_16 PF13191.6 KFR04917.1 - 0.74 10.2 0.0 0.74 10.2 0.0 5.4 2 1 0 2 2 2 0 AAA ATPase domain WW_FCH_linker PF16623.5 KFR04919.1 - 1.9e-35 121.5 1.2 6.3e-35 119.8 1.2 1.9 1 0 0 1 1 1 1 Unstructured linker region between on GAS7 protein FCH PF00611.23 KFR04919.1 - 1.3e-14 54.2 4.2 1.3e-14 54.2 4.2 2.2 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain WW PF00397.26 KFR04919.1 - 7e-13 48.4 3.4 1.4e-12 47.4 3.4 1.6 1 0 0 1 1 1 1 WW domain DUF1664 PF07889.12 KFR04919.1 - 0.013 15.6 4.4 0.013 15.6 4.4 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) PMC2NT PF08066.12 KFR04919.1 - 0.69 10.6 5.7 12 6.7 0.3 2.9 1 1 2 3 3 3 0 PMC2NT (NUC016) domain Lectin_N PF03954.14 KFR04919.1 - 0.82 9.4 5.9 0.29 10.9 2.4 2.0 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Nup54 PF13874.6 KFR04919.1 - 7.9 6.6 16.9 0.29 11.2 7.6 2.4 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 7tm_2 PF00002.24 KFR04920.1 - 7.9e-80 267.7 18.0 1e-79 267.3 18.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFR04920.1 - 2.2e-14 53.5 4.2 4.9e-14 52.4 4.2 1.6 1 0 0 1 1 1 1 Hormone receptor domain SUR7 PF06687.12 KFR04920.1 - 0.00086 19.0 0.5 0.0018 17.9 0.0 1.7 2 0 0 2 2 2 1 SUR7/PalI family GSG-1 PF07803.11 KFR04921.1 - 4.7e-47 158.7 0.3 9.2e-47 157.8 0.3 1.5 1 0 0 1 1 1 1 GSG1-like protein PMP22_Claudin PF00822.20 KFR04921.1 - 8.5e-09 35.5 9.6 1.5e-08 34.7 9.4 1.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFR04921.1 - 6.2e-07 29.4 12.5 3.7e-06 26.8 12.5 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HMGIC_fpl PF10242.9 KFR04921.1 - 0.0019 18.4 8.5 0.0059 16.8 8.5 1.8 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein adh_short PF00106.25 KFR04922.1 - 3.4e-41 140.9 0.0 4.6e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFR04922.1 - 7.5e-23 81.3 0.0 9.4e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFR04922.1 - 4.2e-06 26.8 0.0 5.6e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFR04922.1 - 0.00015 21.3 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) BASP1 PF05466.12 KFR04936.1 - 3.4e-97 325.1 97.2 3.8e-97 325.0 97.2 1.0 1 0 0 1 1 1 1 Brain acid soluble protein 1 (BASP1 protein) Pex24p PF06398.11 KFR04937.1 - 0.14 11.2 0.1 0.26 10.2 0.1 1.4 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Reticulon PF02453.17 KFR04937.1 - 0.39 10.7 4.5 0.88 9.5 4.5 1.6 1 1 0 1 1 1 0 Reticulon zf-C2H2_2 PF12756.7 KFR04938.1 - 7e-37 125.8 11.1 1.6e-29 102.2 0.3 3.4 2 1 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KFR04938.1 - 5.6e-12 45.6 14.6 4.1e-07 30.1 3.8 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFR04938.1 - 4.5e-05 23.7 3.4 4.5e-05 23.7 3.4 3.6 4 0 0 4 4 3 1 Zinc-finger of C2H2 type DUF4637 PF15470.6 KFR04938.1 - 8.4e-05 22.4 0.5 0.00021 21.1 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4637) DUF629 PF04780.12 KFR04938.1 - 0.0014 17.3 4.1 0.039 12.5 0.8 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.6 KFR04938.1 - 0.0077 17.0 0.8 0.0077 17.0 0.8 4.4 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFR04938.1 - 0.0082 16.1 1.7 0.0082 16.1 1.7 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-DBF PF07535.12 KFR04938.1 - 0.053 13.6 0.9 0.053 13.6 0.9 3.0 3 0 0 3 3 3 0 DBF zinc finger zf-LYAR PF08790.11 KFR04938.1 - 0.069 13.1 7.5 2.1 8.3 0.2 3.3 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger GCP5-Mod21 PF14609.6 KFR04938.1 - 0.31 9.3 6.1 0.52 8.6 6.1 1.3 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 zf-C2H2 PF00096.26 KFR04938.1 - 0.78 10.3 22.5 0.2 12.1 2.0 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type DNA_pol_phi PF04931.13 KFR04938.1 - 4.3 5.3 14.8 0.066 11.3 6.7 1.8 2 0 0 2 2 2 0 DNA polymerase phi TRAP_alpha PF03896.16 KFR04938.1 - 9.7 5.3 9.1 0.75 9.0 3.5 1.8 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit LRR_6 PF13516.6 KFR04939.1 - 2.5e-30 101.9 3.6 0.015 15.3 0.0 10.8 11 0 0 11 11 11 9 Leucine Rich repeat F-box-like PF12937.7 KFR04939.1 - 8.1e-17 60.9 4.2 2.3e-16 59.4 4.2 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KFR04939.1 - 1.2e-16 60.6 0.0 0.011 16.1 0.0 6.6 3 2 4 7 7 7 6 Leucine Rich repeats (2 copies) F-box PF00646.33 KFR04939.1 - 4.2e-12 45.6 1.9 4.2e-12 45.6 1.9 2.7 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.33 KFR04939.1 - 6.3e-12 44.3 6.8 2.9 8.8 0.0 10.2 10 1 0 10 10 10 2 Leucine Rich Repeat ANKH PF07260.11 KFR04942.1 - 9.9e-221 731.9 5.6 1.2e-220 731.6 5.6 1.1 1 0 0 1 1 1 1 Progressive ankylosis protein (ANKH) UCR_Fe-S_N PF10399.9 KFR04942.1 - 0.83 9.1 0.0 0.83 9.1 0.0 3.7 4 0 0 4 4 4 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Peptidase_C101 PF16218.5 KFR04943.1 - 1.8e-128 427.4 1.0 2.1e-128 427.2 1.0 1.0 1 0 0 1 1 1 1 Peptidase family C101 Peptidase_C65 PF10275.9 KFR04943.1 - 0.00067 19.2 1.7 0.0046 16.4 1.8 2.3 1 1 1 2 2 2 1 Peptidase C65 Otubain FliS PF02561.14 KFR04943.1 - 0.1 12.9 1.7 0.1 12.9 0.4 1.8 2 1 0 2 2 2 0 Flagellar protein FliS Peptidase_C101 PF16218.5 KFR04944.1 - 1.4e-115 385.1 1.6 1.8e-115 384.8 1.6 1.1 1 0 0 1 1 1 1 Peptidase family C101 Peptidase_C65 PF10275.9 KFR04944.1 - 0.062 12.7 0.7 0.83 9.1 0.1 2.5 2 1 1 3 3 3 0 Peptidase C65 Otubain SRR PF07709.11 KFR04944.1 - 0.11 13.0 0.7 39 5.3 0.3 3.2 2 0 0 2 2 2 0 Seven Residue Repeat DUF4462 PF14692.6 KFR04945.1 - 0.078 12.5 0.5 0.13 11.7 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) DHC_N1 PF08385.12 KFR04946.1 - 7.1e-177 589.5 16.0 7.1e-177 589.5 16.0 4.2 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 KFR04946.1 - 4.8e-145 482.6 0.0 5.9e-144 479.0 0.0 2.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KFR04946.1 - 1.1e-122 410.0 8.3 1.1e-122 410.0 8.3 4.5 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 KFR04946.1 - 3.2e-98 328.7 0.3 7.2e-97 324.3 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 KFR04946.1 - 1.7e-94 316.0 0.2 8.4e-94 313.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KFR04946.1 - 1.4e-84 282.7 2.6 1.4e-84 282.7 2.6 4.3 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 KFR04946.1 - 2.6e-72 242.1 0.3 2.1e-65 219.6 0.1 3.8 3 0 0 3 3 3 3 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KFR04946.1 - 3.2e-55 186.4 0.2 8.8e-55 185.0 0.2 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KFR04946.1 - 6.2e-43 147.1 12.9 1.2e-42 146.2 12.9 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KFR04946.1 - 1.7e-41 141.1 1.2 6.6e-40 135.9 0.0 3.8 4 0 0 4 4 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KFR04946.1 - 1.3e-22 80.3 0.0 6.9e-07 29.3 0.0 5.7 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KFR04946.1 - 7.3e-19 67.8 0.0 3.4e-18 65.7 0.0 2.3 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 KFR04946.1 - 9.1e-19 67.8 0.3 1.8e-17 63.6 0.2 3.2 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KFR04946.1 - 4.6e-06 27.1 0.0 1.7 9.0 0.0 4.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFR04946.1 - 1.1e-05 25.8 0.1 0.32 11.3 0.0 5.1 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 KFR04946.1 - 5.6e-05 23.4 0.4 2 8.7 0.0 4.2 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KFR04946.1 - 0.0057 16.4 3.6 21 4.8 0.3 4.7 4 0 0 4 4 4 0 AAA domain Roc PF08477.13 KFR04946.1 - 0.0079 16.4 0.0 1.8 8.8 0.0 3.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Sigma54_activat PF00158.26 KFR04946.1 - 0.04 13.6 0.2 2.6 7.7 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain TniB PF05621.11 KFR04946.1 - 0.056 12.8 0.1 1.2 8.5 0.0 2.8 2 0 0 2 2 2 0 Bacterial TniB protein LOH1CR12 PF10158.9 KFR04946.1 - 0.083 12.9 2.7 2.6 8.1 0.2 4.1 2 0 0 2 2 2 0 Tumour suppressor protein AAA_33 PF13671.6 KFR04946.1 - 0.13 12.4 0.1 6.6 6.9 0.0 3.4 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.27 KFR04946.1 - 0.16 12.5 5.0 12 6.4 0.0 4.3 4 0 0 4 4 2 0 ABC transporter FtsK_SpoIIIE PF01580.18 KFR04946.1 - 0.18 11.2 0.9 0.98 8.7 0.0 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_19 PF13245.6 KFR04946.1 - 0.3 11.4 8.3 47 4.3 0.0 4.9 4 0 0 4 4 4 0 AAA domain Mg_chelatase PF01078.21 KFR04946.1 - 0.41 10.0 3.6 14 5.0 0.2 3.3 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI Arm PF00514.23 KFR04951.1 - 9.6e-49 162.0 8.5 2.4e-09 36.9 0.1 8.8 9 0 0 9 9 9 6 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KFR04951.1 - 2.6e-08 34.1 0.9 0.0061 16.9 0.0 3.3 2 2 1 3 3 3 3 HEAT repeats HEAT PF02985.22 KFR04951.1 - 9.2e-05 22.4 4.8 0.33 11.3 0.0 5.5 6 0 0 6 6 6 1 HEAT repeat Adaptin_N PF01602.20 KFR04951.1 - 0.0052 15.4 0.0 0.38 9.3 0.0 2.2 2 0 0 2 2 2 2 Adaptin N terminal region Atx10homo_assoc PF09759.9 KFR04951.1 - 0.0093 16.0 0.8 0.52 10.4 0.0 3.4 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 KFR04951.1 - 0.011 16.2 4.1 28 5.3 0.1 5.0 4 1 1 5 5 5 0 HEAT-like repeat DAP PF15228.6 KFR04953.1 - 2.5e-29 102.4 7.0 2.7e-29 102.2 7.0 1.0 1 0 0 1 1 1 1 Death-associated protein Ank_5 PF13857.6 KFR04954.1 - 1.5e-15 57.0 1.9 8.4e-07 29.2 0.3 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFR04954.1 - 5.1e-15 55.8 0.3 1.1e-14 54.7 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFR04954.1 - 9.9e-15 54.7 0.8 4.7e-07 30.2 0.0 3.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFR04954.1 - 2.5e-07 30.4 0.3 0.12 13.0 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KFR04954.1 - 6.5e-07 29.5 0.4 0.00043 20.6 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Phage_Gp23 PF10669.9 KFR04954.1 - 3.7 7.9 6.3 9.4 6.6 6.3 1.6 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF2373 PF10180.9 KFR04956.1 - 0.054 13.3 0.0 0.098 12.5 0.0 1.5 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) RINGv PF12906.7 KFR04957.1 - 8.7e-15 54.6 8.6 2e-14 53.5 8.6 1.7 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KFR04957.1 - 1.7 9.0 15.7 0.058 13.7 9.3 2.0 2 0 0 2 2 2 0 Ring finger domain DLH PF01738.18 KFR04958.1 - 2.6e-36 125.2 0.0 3e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KFR04958.1 - 3.3e-08 33.6 0.0 4.6e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KFR04958.1 - 1.7e-06 27.7 0.0 0.05 13.1 0.0 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KFR04958.1 - 2e-06 27.7 0.1 0.002 17.8 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KFR04958.1 - 1.1e-05 25.4 0.0 0.079 12.8 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KFR04958.1 - 5.9e-05 22.1 0.0 8.9e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KFR04958.1 - 0.00034 19.7 0.0 0.00048 19.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 KFR04958.1 - 0.00035 19.9 0.1 0.085 12.1 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 KFR04958.1 - 0.00085 19.0 0.1 0.0072 16.0 0.1 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF915 PF06028.11 KFR04958.1 - 0.002 17.5 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.7 KFR04958.1 - 0.0038 17.8 0.0 0.0046 17.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 KFR04958.1 - 0.057 13.3 0.1 0.42 10.5 0.0 2.1 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal PAF-AH_p_II PF03403.13 KFR04958.1 - 0.079 11.5 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF676 PF05057.14 KFR04958.1 - 0.15 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Cutinase PF01083.22 KFR04958.1 - 0.21 11.5 0.0 0.47 10.4 0.0 1.5 1 1 0 1 1 1 0 Cutinase DLH PF01738.18 KFR04959.1 - 9.4e-43 146.3 0.0 1.1e-42 146.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KFR04959.1 - 1.4e-06 28.3 0.0 1.9e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KFR04959.1 - 7.2e-06 25.8 0.1 0.0068 16.1 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFR04959.1 - 3.3e-05 23.5 0.0 0.0024 17.4 0.0 2.2 1 1 1 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KFR04959.1 - 0.0016 17.8 0.0 0.69 9.1 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DUF915 PF06028.11 KFR04959.1 - 0.0019 17.6 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.7 KFR04959.1 - 0.0068 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KFR04959.1 - 0.022 14.6 0.0 0.075 12.9 0.0 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.18 KFR04960.1 - 2.1e-40 138.6 0.0 2.4e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KFR04960.1 - 1.7e-08 34.5 0.0 2.4e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KFR04960.1 - 0.00015 21.3 0.2 0.0016 17.9 0.0 2.2 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KFR04960.1 - 0.00047 19.9 0.1 0.011 15.4 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFR04960.1 - 0.0031 16.8 0.1 1.5 8.0 0.0 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DUF1935 PF09149.10 KFR04960.1 - 0.062 13.7 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) Abhydrolase_3 PF07859.13 KFR04960.1 - 0.096 12.5 0.0 0.29 10.9 0.0 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold Pkinase PF00069.25 KFR04961.1 - 5.6e-44 150.5 0.0 7e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR04961.1 - 1.8e-21 76.6 0.0 2.1e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR04961.1 - 4.5e-05 22.9 0.0 0.00013 21.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KFR04961.1 - 0.01 15.5 0.0 0.98 9.0 0.0 2.1 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Cpn60_TCP1 PF00118.24 KFR04962.1 - 1e-160 535.6 4.9 1.3e-160 535.3 4.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Methyltransf_23 PF13489.6 KFR04963.1 - 4.1e-05 23.5 0.0 5.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFR04963.1 - 0.0011 19.7 0.0 0.0021 18.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFR04963.1 - 0.0061 16.4 0.0 0.0089 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFR04963.1 - 0.018 14.4 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) AdoMet_MTase PF07757.13 KFR04963.1 - 0.019 15.3 0.0 0.032 14.6 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MTS PF05175.14 KFR04963.1 - 0.056 13.0 0.0 0.069 12.7 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 KFR04963.1 - 0.11 13.2 0.0 0.19 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain N6_N4_Mtase PF01555.18 KFR04963.1 - 0.12 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 DNA methylase Methyltransf_18 PF12847.7 KFR04963.1 - 0.17 11.8 0.0 0.48 10.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain UCR_Fe-S_N PF10399.9 KFR04963.1 - 0.89 9.0 3.2 1.9 7.9 3.2 1.5 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Sema PF01403.19 KFR04965.1 - 1.3e-114 383.4 0.0 1.8e-114 382.9 0.0 1.2 1 0 0 1 1 1 1 Sema domain TSP_1 PF00090.19 KFR04965.1 - 7.4e-47 157.4 94.6 8.2e-12 45.2 5.2 7.5 7 0 0 7 7 7 6 Thrombospondin type 1 domain RVT_1 PF00078.27 KFR04966.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) FAD_binding_1 PF00667.20 KFR04968.1 - 2.5e-46 158.1 0.0 3.8e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFR04968.1 - 5.9e-29 101.1 0.0 1.1e-28 100.3 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KFR04968.1 - 3.7e-10 40.4 0.0 1.4e-09 38.6 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KFR04968.1 - 2e-06 28.1 0.0 4.1e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain FAST_2 PF08368.12 KFR04969.1 - 7.4e-24 84.4 0.7 2.1e-23 82.9 0.2 2.1 2 0 0 2 2 2 1 FAST kinase-like protein, subdomain 2 FAST_1 PF06743.15 KFR04969.1 - 5.2e-20 71.2 1.7 5.2e-20 71.2 1.7 3.7 3 1 1 4 4 4 1 FAST kinase-like protein, subdomain 1 RAP PF08373.10 KFR04969.1 - 1.7e-12 47.3 0.0 3.9e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 RAP domain RNA_pol_N PF01194.17 KFR04969.1 - 0.13 12.6 0.2 0.51 10.7 0.1 2.0 2 0 0 2 2 2 0 RNA polymerases N / 8 kDa subunit LAGLIDADG_WhiA PF14527.6 KFR04969.1 - 0.15 12.2 0.1 0.4 10.8 0.1 1.7 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain DUF4541 PF15074.6 KFR04970.1 - 6e-27 94.1 0.0 6.3e-27 94.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4541) Guanylate_cyc PF00211.20 KFR04971.1 - 5.7e-122 404.2 1.3 1.3e-64 217.2 0.1 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF1053 PF06327.14 KFR04971.1 - 1.4e-36 125.2 0.6 2.5e-36 124.3 0.6 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) AC_N PF16214.5 KFR04971.1 - 2.3e-26 92.9 11.0 2.3e-26 92.9 11.0 2.1 3 0 0 3 3 3 1 Adenylyl cyclase N-terminal extracellular and transmembrane region HNOBA PF07701.14 KFR04971.1 - 0.019 14.4 1.2 0.079 12.4 0.4 2.1 2 0 0 2 2 2 0 Heme NO binding associated DUF349 PF03993.12 KFR04971.1 - 0.98 9.8 5.8 2.1 8.7 0.3 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Steroid_dh PF02544.16 KFR04972.1 - 2.1e-43 147.9 0.3 2.4e-43 147.7 0.3 1.0 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KFR04972.1 - 1.9e-06 27.6 0.1 2e-06 27.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Methyltr_RsmB-F PF01189.17 KFR04973.1 - 1e-39 136.3 0.0 9.5e-36 123.3 0.0 2.4 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KFR04973.1 - 0.0039 17.3 0.0 0.0077 16.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase UQ_con PF00179.26 KFR04974.1 - 4.6e-11 42.5 0.0 7.7e-11 41.8 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFR04974.1 - 0.00012 21.8 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B Med10 PF09748.9 KFR04975.1 - 1.4e-37 128.3 0.4 1.6e-37 128.2 0.4 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Sigma70_r1_1 PF03979.14 KFR04975.1 - 0.028 14.5 2.2 3.2 7.9 0.1 2.3 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 DUF3198 PF11433.8 KFR04975.1 - 0.032 14.1 0.0 0.078 12.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3198) IL12 PF03039.14 KFR04975.1 - 0.041 13.2 0.0 0.047 13.0 0.0 1.1 1 0 0 1 1 1 0 Interleukin-12 alpha subunit YlbD_coat PF14071.6 KFR04975.1 - 0.16 12.3 1.0 0.8 10.0 0.1 2.2 1 1 2 3 3 3 0 Putative coat protein DUF5524 PF17662.1 KFR04976.1 - 9.7e-86 287.7 9.0 1.2e-85 287.5 9.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5524) PNP_UDP_1 PF01048.20 KFR04977.1 - 1.6e-22 79.9 0.0 1.9e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily GyrB_insert PF18053.1 KFR04978.1 - 0.045 13.6 0.1 0.11 12.4 0.0 1.7 1 1 1 2 2 2 0 DNA gyrase B subunit insert domain DUF1892 PF08987.10 KFR04980.1 - 0.46 10.7 4.2 0.42 10.8 0.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1892) ABC_tran PF00005.27 KFR04981.1 - 2.6e-56 190.0 0.0 6.5e-32 110.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KFR04981.1 - 8.6e-51 173.1 44.4 1.4e-30 106.7 14.3 2.8 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KFR04981.1 - 1.4e-21 77.6 0.5 9e-07 29.0 0.0 4.4 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KFR04981.1 - 6.5e-05 22.7 0.0 0.021 14.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFR04981.1 - 0.00021 21.0 3.7 0.016 15.0 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KFR04981.1 - 0.00026 21.5 8.1 0.0021 18.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KFR04981.1 - 0.0014 18.6 0.4 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 KFR04981.1 - 0.002 17.6 0.2 1.3 8.4 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFR04981.1 - 0.0097 16.3 0.1 0.45 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFR04981.1 - 0.011 16.1 1.8 1.1 9.5 0.0 3.8 4 0 0 4 4 3 0 AAA domain MukB PF04310.12 KFR04981.1 - 0.011 15.6 1.0 3.6 7.3 0.1 2.3 2 0 0 2 2 2 0 MukB N-terminal Mg_chelatase PF01078.21 KFR04981.1 - 0.013 14.9 0.2 0.058 12.8 0.1 2.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KFR04981.1 - 0.033 13.5 0.1 1.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_27 PF13514.6 KFR04981.1 - 0.063 12.9 0.3 3.3 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KFR04981.1 - 0.064 13.2 0.1 0.99 9.3 0.0 2.7 2 0 0 2 2 2 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 KFR04981.1 - 0.11 12.6 0.6 8.3 6.5 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRP54 PF00448.22 KFR04981.1 - 0.13 11.9 1.5 1.2 8.8 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.9 KFR04981.1 - 0.19 10.6 0.6 1.2 8.0 0.0 2.4 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_28 PF13521.6 KFR04981.1 - 0.56 10.4 2.1 20 5.4 0.2 2.3 2 0 0 2 2 2 0 AAA domain VWC PF00093.18 KFR04983.1 - 3.2e-12 46.6 50.9 1.1e-09 38.5 16.4 3.1 3 0 0 3 3 3 3 von Willebrand factor type C domain Pacifastin_I PF05375.13 KFR04983.1 - 4.2e-05 23.2 4.1 4.2e-05 23.2 4.1 4.3 4 1 0 4 4 4 2 Pacifastin inhibitor (LCMII) zf-CCCH_2 PF14608.6 KFR04983.1 - 0.015 15.8 3.4 0.17 12.4 0.9 4.8 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger zf-H2C2_2 PF13465.6 KFR04985.1 - 5e-19 67.8 33.7 1.5e-06 28.3 0.2 6.1 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFR04985.1 - 5.7e-16 58.0 44.9 1e-05 25.7 0.4 6.5 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR04985.1 - 3.5e-10 39.8 41.8 0.0002 21.9 0.4 6.6 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFR04985.1 - 0.0057 16.4 0.2 0.0057 16.4 0.2 4.4 4 0 0 4 4 4 1 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KFR04985.1 - 0.0061 16.3 0.1 0.0061 16.3 0.1 5.2 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFR04985.1 - 0.012 15.9 25.4 0.44 10.9 0.0 5.7 5 1 1 6 6 6 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFR04985.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.6 2 1 1 3 3 3 0 GAGA factor zf-met PF12874.7 KFR04985.1 - 0.25 11.8 0.1 0.25 11.8 0.1 5.8 6 0 0 6 6 6 0 Zinc-finger of C2H2 type RNA_POL_M_15KD PF02150.16 KFR04985.1 - 0.49 10.3 11.4 6.4 6.7 0.0 5.2 6 0 0 6 6 6 0 RNA polymerases M/15 Kd subunit zf-RRPl_C4 PF17026.5 KFR04985.1 - 2.4 8.3 10.3 0.26 11.4 1.3 3.1 3 0 0 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type zinc_ribbon_5 PF13719.6 KFR04985.1 - 6.6 6.6 12.7 0.3 10.9 0.3 3.6 4 0 0 4 4 4 0 zinc-ribbon domain AAA PF00004.29 KFR04986.1 - 2.8e-37 128.1 0.0 5.4e-37 127.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KFR04986.1 - 3.6e-08 33.3 0.0 1.2e-07 31.7 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 KFR04986.1 - 6.9e-08 32.2 0.0 3.8e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 KFR04986.1 - 0.00014 21.7 0.0 0.00026 20.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFR04986.1 - 0.00082 19.8 0.9 0.34 11.3 0.1 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 KFR04986.1 - 0.0017 18.4 0.1 0.0076 16.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFR04986.1 - 0.0052 16.9 0.0 0.011 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFR04986.1 - 0.015 15.6 1.4 0.51 10.6 0.3 2.6 1 1 1 2 2 2 0 AAA domain TIP49 PF06068.13 KFR04986.1 - 0.034 13.3 0.1 0.078 12.2 0.1 1.4 1 1 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 KFR04986.1 - 0.088 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KFR04986.1 - 0.14 11.6 0.1 0.33 10.3 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Pyridoxal_deC PF00282.19 KFR04987.1 - 4.8e-79 265.8 0.2 6.1e-79 265.4 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain CbtA_toxin PF06755.12 KFR04987.1 - 0.098 12.7 0.0 0.73 9.9 0.0 2.3 1 1 1 2 2 2 0 CbtA_toxin of type IV toxin-antitoxin system Reprolysin PF01421.19 KFR05000.1 - 9.9e-62 208.4 0.0 2.2e-61 207.3 0.0 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.12 KFR05000.1 - 1.9e-24 86.3 5.3 1.9e-24 86.3 5.3 3.6 3 2 0 3 3 3 1 ADAM cysteine-rich Disintegrin PF00200.23 KFR05000.1 - 4.2e-15 56.3 29.9 4.2e-15 56.3 29.9 3.6 3 1 0 3 3 3 1 Disintegrin Pep_M12B_propep PF01562.19 KFR05000.1 - 8.9e-15 55.1 1.4 1.4e-14 54.5 0.3 1.8 2 0 0 2 2 2 1 Reprolysin family propeptide Reprolysin_3 PF13582.6 KFR05000.1 - 7.3e-10 39.4 0.0 1.2e-09 38.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFR05000.1 - 4.4e-09 36.8 0.2 8.7e-09 35.8 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 EGF_2 PF07974.13 KFR05000.1 - 0.00049 20.4 10.7 0.00049 20.4 10.7 6.0 6 1 0 6 6 6 2 EGF-like domain Reprolysin_2 PF13574.6 KFR05000.1 - 0.0011 18.9 0.0 0.0029 17.5 0.0 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_Tenascin PF18720.1 KFR05000.1 - 0.0014 18.6 3.4 0.0014 18.6 3.4 3.6 4 0 0 4 4 4 1 Tenascin EGF domain Connexin PF00029.19 KFR05001.1 - 3e-97 325.0 0.2 3.4e-97 324.8 0.2 1.0 1 0 0 1 1 1 1 Connexin TLP-20 PF06088.11 KFR05001.1 - 0.076 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) GTP_EFTU PF00009.27 KFR05002.1 - 6.2e-46 156.4 0.0 9.5e-46 155.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KFR05002.1 - 1.1e-38 132.6 9.2 1.8e-38 131.9 9.2 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KFR05002.1 - 1.2e-23 83.2 0.0 2.5e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KFR05002.1 - 9.9e-23 80.0 0.0 2.2e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFR05002.1 - 1e-12 48.3 0.0 2.7e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KFR05002.1 - 3.1e-08 33.6 0.0 8.4e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Septin PF00735.18 KFR05002.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Septin RPAP3_C PF13877.6 KFR05003.1 - 1.7e-20 73.3 0.0 3.1e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 Dynein_attach_N PF15867.5 KFR05003.1 - 1.2e-06 28.4 0.1 2.2e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 Dynein attachment factor N-terminus V-set PF07686.17 KFR05004.1 - 2.5e-11 43.7 0.0 4.9e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.6 KFR05004.1 - 1.2e-07 32.3 0.0 0.016 15.8 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFR05004.1 - 5.4e-06 26.5 0.0 0.14 12.3 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFR05004.1 - 2e-05 24.6 0.0 0.081 13.0 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFR05004.1 - 0.00025 21.3 0.0 0.045 14.1 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin domain Ig_6 PF18452.1 KFR05004.1 - 0.0012 18.4 0.0 0.4 10.3 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Filament PF00038.21 KFR05005.1 - 1.4e-109 366.4 43.9 1.7e-109 366.2 43.9 1.0 1 0 0 1 1 1 1 Intermediate filament protein DUF1664 PF07889.12 KFR05005.1 - 0.00028 20.9 7.4 0.13 12.4 0.2 3.4 2 1 0 3 3 3 2 Protein of unknown function (DUF1664) Filament_head PF04732.14 KFR05005.1 - 0.00028 21.7 0.8 0.00059 20.6 0.3 1.8 2 0 0 2 2 1 1 Intermediate filament head (DNA binding) region TolA_bind_tri PF16331.5 KFR05005.1 - 0.0022 18.0 4.2 0.0022 18.0 4.2 5.1 2 1 1 4 4 3 1 TolA binding protein trimerisation Phage_GP20 PF06810.11 KFR05005.1 - 0.012 15.4 2.5 0.012 15.4 2.5 3.6 1 1 2 3 3 3 0 Phage minor structural protein GP20 Baculo_PEP_C PF04513.12 KFR05005.1 - 0.024 14.7 14.9 0.96 9.5 0.2 4.2 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 KFR05005.1 - 0.037 12.9 38.6 0.4 9.5 3.1 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein HALZ PF02183.18 KFR05005.1 - 0.066 13.4 1.1 0.066 13.4 1.1 5.2 6 0 0 6 6 5 0 Homeobox associated leucine zipper DUF573 PF04504.14 KFR05005.1 - 0.29 11.8 4.1 0.45 11.2 0.2 3.0 2 2 1 3 3 3 0 Protein of unknown function, DUF573 BLOC1_2 PF10046.9 KFR05005.1 - 0.33 11.3 22.3 0.064 13.6 2.0 4.6 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.6 KFR05005.1 - 0.37 10.1 37.4 0.045 13.1 11.2 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Syntaxin_2 PF14523.6 KFR05005.1 - 0.5 10.8 11.0 3.1 8.2 3.6 3.5 3 2 0 3 3 3 0 Syntaxin-like protein LURAP PF14854.6 KFR05005.1 - 0.53 10.3 6.9 0.7 9.9 0.4 3.4 2 2 1 3 3 3 0 Leucine rich adaptor protein DUF4407 PF14362.6 KFR05005.1 - 0.6 9.4 28.2 4.1 6.7 13.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Hydantoinase_B PF02538.14 KFR05005.1 - 0.72 8.2 2.8 0.43 8.9 0.9 1.6 1 1 1 2 2 2 0 Hydantoinase B/oxoprolinase DUF5082 PF16888.5 KFR05005.1 - 0.76 10.1 18.5 0.43 10.9 3.8 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF5082) Jnk-SapK_ap_N PF09744.9 KFR05005.1 - 0.81 9.9 39.2 0.35 11.1 9.2 3.6 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Fib_alpha PF08702.10 KFR05005.1 - 2.6 8.2 17.7 3.6 7.8 1.1 3.8 1 1 4 5 5 5 0 Fibrinogen alpha/beta chain family DUF4515 PF14988.6 KFR05005.1 - 2.9 7.7 37.8 3.4 7.5 26.3 3.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4515) TPR_MLP1_2 PF07926.12 KFR05005.1 - 3.2 7.8 47.3 0.64 10.1 12.7 4.3 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 KFR05005.1 - 4.3 6.7 34.3 0.61 9.5 7.0 3.1 1 1 2 3 3 3 0 Golgin subfamily A member 5 YabA PF06156.13 KFR05005.1 - 4.3 8.0 31.7 0.23 12.1 1.9 5.1 2 2 3 5 5 5 0 Initiation control protein YabA WXG100 PF06013.12 KFR05005.1 - 6 7.2 13.6 3.6 7.9 4.5 3.8 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Cortex-I_coil PF09304.10 KFR05005.1 - 7.4 6.8 30.2 0.73 10.1 7.6 4.5 1 1 2 4 4 4 0 Cortexillin I, coiled coil Trimer_CC PF08954.11 KFR05005.1 - 8 6.1 14.7 0.12 12.0 0.4 4.0 3 1 0 3 3 3 0 Trimerisation motif Kinesin PF00225.23 KFR05006.1 - 6.1e-112 373.8 0.1 2.5e-111 371.8 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFR05006.1 - 2.4e-25 89.2 0.0 5.3e-25 88.1 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding C1q PF00386.21 KFR05007.1 - 1.9e-17 63.6 0.0 2.1e-17 63.5 0.0 1.0 1 0 0 1 1 1 1 C1q domain CoaE PF01121.20 KFR05008.1 - 8.2e-63 211.3 0.0 9.9e-63 211.0 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KFR05008.1 - 0.00029 21.4 0.0 0.0019 18.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFR05008.1 - 0.00097 19.3 0.0 0.0044 17.2 0.0 2.1 1 1 1 2 2 2 1 AAA domain HicA_toxin PF07927.12 KFR05008.1 - 0.015 15.4 0.2 0.29 11.2 0.1 2.6 3 0 0 3 3 3 0 HicA toxin of bacterial toxin-antitoxin, AAA_17 PF13207.6 KFR05008.1 - 0.027 14.9 0.1 0.34 11.3 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.6 KFR05008.1 - 0.039 14.2 0.2 0.16 12.2 0.2 2.2 1 1 0 1 1 1 0 AAA domain CytB6-F_Fe-S PF08802.10 KFR05008.1 - 0.47 10.5 4.7 11 6.1 0.6 3.0 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit NMT_C PF02799.15 KFR05009.1 - 8e-84 280.3 0.1 1.2e-83 279.8 0.1 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KFR05009.1 - 1.6e-74 249.1 0.0 2.9e-74 248.2 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 KFR05009.1 - 0.00016 21.9 0.0 0.00039 20.6 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KFR05009.1 - 0.053 13.6 0.0 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF4276 PF14103.6 KFR05009.1 - 0.069 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4276) Pkinase PF00069.25 KFR05011.1 - 1.1e-23 84.0 0.0 1.3e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR05011.1 - 4.5e-07 29.4 0.0 6.3e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR05011.1 - 0.016 14.5 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 KFR05012.1 - 4.4e-46 157.4 0.0 7.1e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR05012.1 - 7e-29 100.9 0.0 1.1e-28 100.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFR05012.1 - 1.5e-05 24.0 0.0 4.7e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase CDK5_activator PF03261.15 KFR05013.1 - 1.5e-94 317.5 1.3 1.7e-94 317.3 1.3 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase 5 activator protein RPN6_N PF18055.1 KFR05014.1 - 3.2e-19 69.4 0.1 3.4e-19 69.3 0.1 1.0 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN6 N-terminal domain SEN1_N PF12726.7 KFR05014.1 - 0.033 12.4 0.0 0.033 12.4 0.0 1.0 1 0 0 1 1 1 0 SEN1 N terminal Frizzled PF01534.17 KFR05015.1 - 9.7e-142 471.8 19.3 1.2e-141 471.4 19.3 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 KFR05015.1 - 6.7e-34 116.9 3.8 1.5e-33 115.7 3.8 1.6 1 0 0 1 1 1 1 Fz domain Granulin PF00396.18 KFR05016.1 - 1.6e-39 133.9 125.7 1.9e-16 60.1 22.3 8.9 10 0 0 10 10 10 6 Granulin Lustrin_cystein PF14625.6 KFR05016.1 - 0.024 15.0 4.6 0.024 15.0 4.6 8.5 5 4 3 8 8 8 0 Lustrin, cysteine-rich repeated domain zf-CCHH PF10283.9 KFR05036.1 - 2.6e-24 84.9 16.7 5.5e-12 45.4 4.0 2.5 2 0 0 2 2 2 2 PBZ domain SsgA PF04686.12 KFR05036.1 - 0.0033 17.4 0.0 0.0065 16.5 0.0 1.4 1 0 0 1 1 1 1 Streptomyces sporulation and cell division protein, SsgA HUN PF08729.10 KFR05036.1 - 0.011 15.7 11.2 0.032 14.2 11.2 1.9 1 0 0 1 1 1 0 HPC2 and ubinuclein domain F-box-like PF12937.7 KFR05037.1 - 2.7e-13 49.6 0.8 3.7e-13 49.1 0.2 1.6 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KFR05037.1 - 4.8e-06 26.3 3.0 5.2e-06 26.2 0.3 2.4 2 1 0 2 2 2 1 F-box domain PH PF00169.29 KFR05038.1 - 3.6e-37 127.1 0.0 7.8e-19 68.1 0.0 2.3 2 0 0 2 2 2 2 PH domain DEP PF00610.21 KFR05038.1 - 2.3e-13 50.0 0.0 4.5e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_9 PF15410.6 KFR05038.1 - 2e-11 44.3 0.3 2.8e-05 24.5 0.0 2.6 2 1 0 2 2 2 2 Pleckstrin homology domain PH_6 PF15406.6 KFR05038.1 - 2.7e-10 40.5 0.0 1.1e-06 29.0 0.0 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH_13 PF16652.5 KFR05038.1 - 7e-06 25.9 0.0 0.093 12.5 0.0 2.2 2 0 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 KFR05038.1 - 0.00012 22.4 3.1 0.12 12.8 0.3 3.9 2 2 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 KFR05038.1 - 0.00079 19.7 0.2 0.064 13.5 0.0 3.4 2 2 0 2 2 2 1 Pleckstrin homology domain PH_2 PF08458.10 KFR05038.1 - 0.013 15.9 0.1 0.4 11.0 0.0 2.2 2 0 0 2 2 2 0 Plant pleckstrin homology-like region PH_16 PF17838.1 KFR05038.1 - 0.11 12.4 0.4 5.9 6.7 0.1 2.6 2 1 0 2 2 2 0 PH domain PH_17 PF18012.1 KFR05038.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 PH domain CNRIP1 PF15043.6 KFR05039.1 - 1e-67 226.6 0.0 1.1e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 CB1 cannabinoid receptor-interacting protein 1 EF-hand_1 PF00036.32 KFR05040.1 - 8.3e-28 93.8 14.2 1.2e-06 27.6 0.4 4.9 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 KFR05040.1 - 5.7e-26 90.8 5.4 2.1e-14 53.7 0.5 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFR05040.1 - 3.7e-22 76.3 6.6 1.3e-05 24.7 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFR05040.1 - 4.3e-22 76.6 9.5 2.5e-05 23.6 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KFR05040.1 - 5.8e-19 67.7 7.4 0.0015 18.4 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFR05040.1 - 5.5e-09 36.3 0.2 0.0015 18.9 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFR05040.1 - 1.8e-07 31.0 4.6 0.0075 16.2 0.2 3.7 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFR05040.1 - 0.00065 20.0 0.2 0.079 13.3 0.0 2.7 2 1 1 3 3 3 1 EF-hand domain Caleosin PF05042.13 KFR05040.1 - 0.029 14.3 3.1 9.7 6.1 0.1 3.4 2 2 2 4 4 4 0 Caleosin related protein Dockerin_1 PF00404.18 KFR05040.1 - 9 6.6 9.8 15 5.9 2.9 3.3 2 2 1 3 3 3 0 Dockerin type I domain KH_8 PF17903.1 KFR05041.1 - 4.4e-05 23.5 0.1 7.6e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KFR05041.1 - 0.00023 20.9 0.8 0.00055 19.7 0.8 1.6 1 0 0 1 1 1 1 KH domain WD40 PF00400.32 KFR05042.1 - 4.7e-13 49.4 2.7 0.0002 22.1 0.0 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR05042.1 - 0.00096 19.4 0.1 1.1 9.7 0.0 2.9 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Itfg2 PF15907.5 KFR05042.1 - 0.0047 16.0 0.2 0.077 12.0 0.0 2.3 1 1 1 2 2 2 1 Integrin-alpha FG-GAP repeat-containing protein 2 BBS2_Mid PF14783.6 KFR05042.1 - 0.013 15.5 0.1 0.31 11.1 0.0 2.7 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.11 KFR05042.1 - 0.025 14.5 0.0 8.1 6.3 0.0 2.9 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A PHTB1_N PF14727.6 KFR05042.1 - 0.13 11.6 0.0 13 5.0 0.0 2.6 2 1 1 3 3 3 0 PTHB1 N-terminus Sas10_Utp3 PF04000.15 KFR05043.1 - 5.7e-17 62.1 0.4 9.4e-17 61.4 0.4 1.3 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DUF932 PF06067.11 KFR05043.1 - 0.02 14.7 0.2 0.02 14.7 0.2 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF932) ING PF12998.7 KFR05043.1 - 0.11 13.0 1.6 2.1 9.0 1.6 2.2 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding ETAA1 PF15350.6 KFR05044.1 - 2.1e-253 843.4 39.0 4.5e-152 508.2 8.9 2.0 1 1 1 2 2 2 2 Ewing's tumour-associated antigen 1 homologue Meis_PKNOX_N PF16493.5 KFR05045.1 - 1.7e-45 153.2 0.2 2.8e-45 152.6 0.2 1.3 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 Homeobox_KN PF05920.11 KFR05045.1 - 1.1e-20 73.2 1.0 2e-20 72.4 1.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFR05045.1 - 2.2e-08 33.8 1.2 3.7e-08 33.1 0.3 1.8 2 0 0 2 2 2 1 Homeodomain Sprouty PF05210.13 KFR05046.1 - 4.9e-29 100.8 25.0 4.9e-29 100.8 25.0 1.8 2 0 0 2 2 2 1 Sprouty protein (Spry) WH1 PF00568.23 KFR05046.1 - 2.5e-10 40.3 0.0 4.1e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 WH1 domain Actin PF00022.19 KFR05047.1 - 1.5e-112 376.2 0.0 1.2e-111 373.2 0.0 1.9 1 1 0 1 1 1 1 Actin Ras PF00071.22 KFR05048.1 - 1.8e-67 226.0 1.1 2.2e-67 225.7 1.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR05048.1 - 8.6e-38 129.2 0.1 1.6e-37 128.4 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR05048.1 - 2e-17 63.2 0.2 2.4e-17 62.9 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFR05048.1 - 6.6e-07 29.4 0.5 0.011 15.6 0.1 2.4 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFR05048.1 - 6.5e-06 25.8 0.3 1.8e-05 24.3 0.2 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFR05048.1 - 7.1e-06 25.5 0.1 9.6e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFR05048.1 - 8.1e-06 25.9 0.1 2.7e-05 24.2 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFR05048.1 - 1.4e-05 24.6 0.1 2.1e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 KFR05048.1 - 0.00084 19.8 0.0 0.12 12.8 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 KFR05048.1 - 0.0034 16.9 0.0 0.018 14.6 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KFR05048.1 - 0.017 15.5 0.0 0.023 15.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 KFR05048.1 - 0.019 14.7 0.1 0.95 9.2 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KFR05048.1 - 0.044 13.3 0.1 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 KFR05048.1 - 0.044 14.0 0.0 0.084 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFR05048.1 - 0.055 14.0 0.0 0.079 13.5 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Septin PF00735.18 KFR05048.1 - 0.061 12.6 0.1 0.13 11.5 0.0 1.6 1 1 0 1 1 1 0 Septin AAA_5 PF07728.14 KFR05048.1 - 0.065 13.2 0.0 0.087 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) LANC_like PF05147.13 KFR05048.1 - 0.074 11.6 0.1 0.16 10.5 0.0 1.5 1 1 1 2 2 2 0 Lanthionine synthetase C-like protein AAA_29 PF13555.6 KFR05048.1 - 0.074 12.8 0.2 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 KFR05048.1 - 0.14 11.5 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein Dioxygenase_N PF04444.14 KFR05048.1 - 0.16 11.8 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Catechol dioxygenase N terminus SDF PF00375.18 KFR05050.1 - 9e-92 308.1 14.5 1e-91 307.9 14.5 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family VMA21 PF09446.10 KFR05050.1 - 0.032 14.3 2.6 0.14 12.3 2.2 2.4 1 1 1 2 2 2 0 VMA21-like domain SERTA PF06031.13 KFR05051.1 - 3.3e-17 61.9 0.8 5.4e-17 61.2 0.8 1.4 1 0 0 1 1 1 1 SERTA motif Gal-bind_lectin PF00337.22 KFR05052.1 - 1.1e-32 112.4 0.0 1.2e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin Kazal_1 PF00050.21 KFR05067.1 - 1.7e-11 44.0 2.6 1.7e-11 43.9 2.6 1.1 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KFR05067.1 - 4e-06 26.8 0.6 4.5e-06 26.7 0.6 1.1 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain 7tm_1 PF00001.21 KFR05068.1 - 9.5e-72 241.5 16.4 1.1e-71 241.3 16.4 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR05068.1 - 1.8e-12 47.2 11.7 2.3e-12 46.9 11.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFR05068.1 - 5.8e-08 32.8 10.6 3e-07 30.5 11.2 1.9 2 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFR05068.1 - 4e-05 23.4 12.4 7.3e-05 22.5 12.4 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx T_cell_tran_alt PF15128.6 KFR05068.1 - 0.16 11.8 1.1 2.6 7.9 0.1 2.5 2 0 0 2 2 2 0 T-cell leukemia translocation-altered Synaphin PF05835.12 KFR05069.1 - 1.1e-39 135.9 17.5 1.3e-39 135.7 17.5 1.0 1 0 0 1 1 1 1 Synaphin protein LD_cluster2 PF18163.1 KFR05069.1 - 0.094 12.2 3.4 0.13 11.8 3.4 1.1 1 0 0 1 1 1 0 SLOG cluster2 Spt5_N PF11942.8 KFR05069.1 - 0.4 11.7 19.4 0.12 13.4 12.2 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal RR_TM4-6 PF06459.12 KFR05069.1 - 0.71 9.6 11.2 0.93 9.3 11.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Borrelia_P83 PF05262.11 KFR05069.1 - 2.9 6.3 14.1 3.2 6.2 14.1 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4407 PF14362.6 KFR05069.1 - 4.3 6.6 7.2 4.8 6.4 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MDM10 PF12519.8 KFR05069.1 - 4.5 6.0 5.8 5.5 5.7 5.8 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 P33MONOX PF15302.6 KFR05071.1 - 7e-139 462.5 9.5 8e-139 462.3 9.5 1.0 1 0 0 1 1 1 1 P33 mono-oxygenase Arf PF00025.21 KFR05072.1 - 7e-40 136.3 0.0 8.9e-40 136.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFR05072.1 - 3.7e-09 36.8 0.0 5.2e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KFR05072.1 - 2.2e-08 33.8 0.0 2.5e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFR05072.1 - 5.9e-07 29.1 0.0 7.4e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KFR05072.1 - 3.1e-06 26.9 0.0 3.6e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KFR05072.1 - 3.1e-05 23.3 0.0 0.00024 20.4 0.0 1.9 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 KFR05072.1 - 5.6e-05 23.2 0.0 9.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFR05072.1 - 0.00021 20.9 0.0 0.00068 19.2 0.0 1.7 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain NACHT PF05729.12 KFR05072.1 - 0.00058 19.8 0.3 0.047 13.6 0.3 2.3 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KFR05072.1 - 0.0042 17.5 3.0 0.031 14.7 3.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 KFR05072.1 - 0.013 15.0 0.0 1.7 8.2 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 KFR05072.1 - 0.15 12.6 0.0 0.16 12.5 0.0 1.5 1 1 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 KFR05072.1 - 0.16 11.8 0.0 5.8 6.8 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Nop16 PF09420.10 KFR05073.1 - 3.3e-21 76.3 0.5 6.4e-14 52.5 0.5 2.1 2 0 0 2 2 2 2 Ribosome biogenesis protein Nop16 Baculo_p33 PF05214.12 KFR05073.1 - 0.0051 16.6 0.3 0.007 16.1 0.3 1.3 1 0 0 1 1 1 1 Baculovirus P33 Chorion_S16 PF05836.12 KFR05073.1 - 0.091 13.0 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Chorion protein S16 HIG_1_N PF04588.13 KFR05074.1 - 7.4e-21 74.1 1.2 9.8e-21 73.7 1.2 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Clathrin_lg_ch PF01086.17 KFR05075.1 - 3.8e-40 138.4 13.7 8.5e-40 137.2 13.7 1.6 1 1 0 1 1 1 1 Clathrin light chain UBA_4 PF14555.6 KFR05076.1 - 1.3e-07 31.3 0.2 6.9e-07 29.0 0.1 2.0 2 0 0 2 2 2 1 UBA-like domain DUF1682 PF07946.14 KFR05076.1 - 8.1e-06 25.3 7.9 1.1e-05 24.8 7.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) UBX PF00789.20 KFR05076.1 - 1.6e-05 25.0 0.2 7.9e-05 22.8 0.2 2.2 1 1 0 1 1 1 1 UBX domain LIM_bind PF01803.16 KFR05076.1 - 0.036 13.6 0.1 0.045 13.3 0.1 1.3 1 0 0 1 1 1 0 LIM-domain binding protein AAA_23 PF13476.6 KFR05076.1 - 0.044 14.3 10.1 0.096 13.2 10.1 1.6 1 0 0 1 1 1 0 AAA domain NARP1 PF12569.8 KFR05076.1 - 0.11 11.4 11.0 0.18 10.7 11.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Serinc PF03348.15 KFR05076.1 - 0.23 10.4 0.4 0.32 9.9 0.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4366 PF14283.6 KFR05076.1 - 0.44 10.6 3.9 0.74 9.8 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Presenilin PF01080.17 KFR05076.1 - 0.86 8.3 6.7 1.2 7.8 6.7 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 KFR05076.1 - 2.5 6.3 9.6 3.3 5.9 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF5401 PF17380.2 KFR05076.1 - 3 5.8 21.3 4.3 5.3 21.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) MRP-S26 PF14943.6 KFR05076.1 - 6.1 6.7 20.3 11 5.9 20.3 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Connexin PF00029.19 KFR05076.1 - 6.3 6.5 5.3 9.9 5.8 5.3 1.3 1 0 0 1 1 1 0 Connexin Cadherin PF00028.17 KFR05077.1 - 6.6e-97 318.2 12.5 1.3e-16 60.8 0.1 9.6 9 1 0 9 9 9 9 Cadherin domain Cadherin_2 PF08266.12 KFR05077.1 - 9.9e-13 47.7 0.0 0.027 14.3 0.0 5.0 4 0 0 4 4 4 4 Cadherin-like Cadherin_3 PF16184.5 KFR05077.1 - 1.8e-07 31.1 23.0 0.7 9.9 0.3 8.8 10 1 0 10 10 10 5 Cadherin-like PepSY PF03413.19 KFR05077.1 - 0.028 15.0 1.7 32 5.2 0.0 4.8 5 0 0 5 5 5 0 Peptidase propeptide and YPEB domain A2M_BRD PF07703.14 KFR05077.1 - 0.084 13.2 4.6 1.7 9.0 0.0 4.8 5 1 0 5 5 5 0 Alpha-2-macroglobulin bait region domain BACON PF13004.7 KFR05077.1 - 0.37 10.8 2.8 1.9 8.5 0.6 3.5 2 0 0 2 2 2 0 Putative binding domain, N-terminal Adeno_E3_CR2 PF02439.15 KFR05077.1 - 1.5 8.7 6.3 7.9 6.3 5.5 2.4 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 He_PIG PF05345.12 KFR05077.1 - 3.7 7.8 8.9 48 4.2 0.4 5.4 5 0 0 5 5 5 0 Putative Ig domain Synuclein PF01387.17 KFR05079.1 - 1.2e-15 57.9 3.3 6.1e-15 55.6 3.3 1.8 1 1 0 1 1 1 1 Synuclein IF4E PF01652.18 KFR05080.1 - 9.3e-56 188.0 1.2 1.1e-55 187.8 1.2 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E UPA PF17217.3 KFR05081.1 - 4.1e-69 230.9 0.1 6.9e-69 230.2 0.1 1.4 1 0 0 1 1 1 1 UPA domain ZU5 PF00791.20 KFR05081.1 - 6.1e-29 100.3 0.0 1.4e-28 99.1 0.0 1.6 1 0 0 1 1 1 1 ZU5 domain Death PF00531.22 KFR05081.1 - 4e-12 46.1 0.0 8.1e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Death domain I-set PF07679.16 KFR05081.1 - 1.3e-11 44.3 0.0 3.8e-09 36.5 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR05081.1 - 2.2e-11 44.2 0.1 7.6e-08 32.9 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain TSP_1 PF00090.19 KFR05081.1 - 1.2e-10 41.4 34.9 4.4e-08 33.2 13.7 2.8 2 0 0 2 2 2 2 Thrombospondin type 1 domain Ig_2 PF13895.6 KFR05081.1 - 3.6e-05 24.0 0.0 0.00038 20.7 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 KFR05081.1 - 0.00011 22.3 0.0 0.028 14.6 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin domain Hexokinase_1 PF00349.21 KFR05082.1 - 2.7e-124 412.6 0.0 4e-66 222.7 0.0 2.1 2 0 0 2 2 2 2 Hexokinase Hexokinase_2 PF03727.16 KFR05082.1 - 7.6e-113 375.8 1.3 7.4e-64 215.4 0.1 2.2 2 0 0 2 2 2 2 Hexokinase RAP80_UIM PF18282.1 KFR05083.1 - 4.8e-34 115.9 11.3 4.8e-34 115.9 11.3 2.3 3 0 0 3 3 3 1 RAP80 N-terminal ubiquitin interaction motif UIM PF02809.20 KFR05083.1 - 0.0037 17.1 11.0 0.035 14.0 2.3 3.0 2 0 0 2 2 2 2 Ubiquitin interaction motif zf-WRNIP1_ubi PF18279.1 KFR05083.1 - 0.068 13.8 0.5 0.24 12.1 0.0 2.3 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-met PF12874.7 KFR05084.1 - 4.9e-22 77.6 17.3 4.5e-07 30.0 0.5 3.4 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFR05084.1 - 1.2e-14 54.2 9.5 0.00016 21.9 1.8 3.5 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 KFR05084.1 - 4.1e-05 23.3 11.1 0.19 11.6 1.5 3.3 3 0 0 3 3 3 3 U1 zinc finger zf-C2H2_2 PF12756.7 KFR05084.1 - 0.00021 21.6 14.4 0.18 12.1 0.5 3.1 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_3 PF13878.6 KFR05084.1 - 0.005 16.6 2.4 0.32 10.8 0.2 3.2 3 0 0 3 3 3 1 zinc-finger of acetyl-transferase ESCO CTU2 PF10288.9 KFR05084.1 - 0.022 15.0 11.9 0.13 12.5 6.1 3.0 1 1 1 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Vps39_2 PF10367.9 KFR05084.1 - 0.13 12.7 6.1 6.7 7.2 0.0 3.0 1 1 2 3 3 3 0 Vacuolar sorting protein 39 domain 2 zf-C2H2_4 PF13894.6 KFR05084.1 - 0.48 11.4 15.7 0.53 11.3 0.4 4.0 4 0 0 4 4 3 0 C2H2-type zinc finger zf-RING_UBOX PF13445.6 KFR05084.1 - 0.84 9.7 0.1 0.84 9.7 0.1 3.2 4 1 0 4 4 4 0 RING-type zinc-finger zf-DBF PF07535.12 KFR05084.1 - 1.3 9.2 8.9 1.1 9.4 0.9 3.2 3 0 0 3 3 3 0 DBF zinc finger His_Me_b4a2 PF18275.1 KFR05084.1 - 1.5 9.0 0.0 1.5 9.0 0.0 3.2 3 1 0 3 3 3 0 His-Me finger endonuclease beta4-alpha2 domain DUF2946 PF11162.8 KFR05084.1 - 1.9 9.1 6.7 2.7 8.7 1.6 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2946) zf_C2H2_6 PF18450.1 KFR05084.1 - 2.2 8.0 7.0 0.22 11.3 0.6 2.5 3 0 0 3 3 3 0 Zinc Finger domain PSCyt3 PF07627.11 KFR05084.1 - 5.4 7.4 7.1 0.49 10.7 1.0 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1588) Pkinase_Tyr PF07714.17 KFR05085.1 - 7.7e-104 346.5 0.0 1e-103 346.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR05085.1 - 2.4e-44 151.7 0.0 3.5e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.16 KFR05085.1 - 2.3e-35 120.5 0.0 2.5e-14 53.1 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR05085.1 - 8.5e-35 119.2 0.0 4.4e-13 49.6 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFR05085.1 - 5.9e-28 97.0 0.0 5.7e-10 39.4 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFR05085.1 - 1.9e-25 88.8 0.0 3.1e-10 40.1 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFR05085.1 - 9.7e-13 48.2 0.2 0.04 14.1 0.1 5.2 3 2 0 3 3 3 3 Immunoglobulin V-set domain Ig_5 PF16681.5 KFR05085.1 - 1.7e-06 28.3 0.0 3.7 8.0 0.0 3.9 3 0 0 3 3 3 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFR05085.1 - 7.2e-06 25.5 0.0 0.9 9.2 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain Ig_4 PF16680.5 KFR05085.1 - 0.0012 19.0 0.0 3.3 8.0 0.0 3.7 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFR05085.1 - 0.0036 17.3 0.0 16 5.6 0.0 3.4 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain FGFR3_TM PF18123.1 KFR05085.1 - 0.0087 15.6 0.1 0.016 14.7 0.1 1.4 1 0 0 1 1 1 1 Fibroblast growth factor receptor 3 transmembrane domain DUF5412 PF17428.2 KFR05085.1 - 0.032 14.1 0.0 0.088 12.7 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5412) Haspin_kinase PF12330.8 KFR05085.1 - 0.047 12.6 0.0 0.083 11.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain C2-set_2 PF08205.12 KFR05085.1 - 0.067 13.3 0.0 0.45 10.6 0.0 2.3 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Pkinase_fungal PF17667.1 KFR05085.1 - 0.075 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KFR05085.1 - 0.11 11.8 0.0 0.29 10.4 0.0 1.6 2 0 0 2 2 2 0 Kinase-like C5HCH PF17982.1 KFR05086.1 - 3.6e-23 81.4 10.4 3.6e-23 81.4 10.4 5.1 3 1 1 4 4 4 1 NSD Cys-His rich domain SET PF00856.28 KFR05086.1 - 1.3e-20 74.5 1.4 1.3e-19 71.2 0.9 2.8 3 1 0 3 3 3 1 SET domain PWWP PF00855.17 KFR05086.1 - 8.8e-19 67.7 0.4 2e-18 66.6 0.4 1.6 1 0 0 1 1 1 1 PWWP domain AWS PF17907.1 KFR05086.1 - 1.4e-17 63.4 7.4 1.4e-17 63.4 7.4 5.7 7 1 0 7 7 7 1 AWS domain PHD PF00628.29 KFR05086.1 - 1.4e-14 53.7 70.3 2e-06 27.6 10.6 6.7 4 2 2 6 6 6 4 PHD-finger PHD_2 PF13831.6 KFR05086.1 - 5.8e-06 25.8 37.4 0.00035 20.0 1.9 5.9 5 1 0 5 5 5 3 PHD-finger Ras PF00071.22 KFR05088.1 - 1.1e-08 34.8 0.0 1.7e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 KFR05088.1 - 0.047 13.6 0.0 0.054 13.4 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase PRELI PF04707.14 KFR05089.1 - 2.3e-39 134.8 0.2 3.2e-39 134.2 0.2 1.2 1 0 0 1 1 1 1 PRELI-like family Hs1pro-1_C PF07014.12 KFR05090.1 - 0.063 12.7 0.0 0.084 12.3 0.0 1.1 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus NARP1 PF12569.8 KFR05091.1 - 0.1 11.5 5.3 0.15 10.9 5.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DEAD PF00270.29 KFR05092.1 - 1.8e-44 151.6 0.0 8e-44 149.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFR05092.1 - 5.3e-32 110.5 0.0 3.8e-30 104.5 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain zf-CCHC PF00098.23 KFR05092.1 - 0.0013 18.7 1.5 0.0026 17.8 1.5 1.5 1 0 0 1 1 1 1 Zinc knuckle ResIII PF04851.15 KFR05092.1 - 0.027 14.5 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 KFR05092.1 - 0.093 12.0 0.0 0.2 10.9 0.0 1.6 1 1 0 1 1 1 0 SecA DEAD-like domain UTP25 PF06862.12 KFR05092.1 - 0.11 11.2 0.0 0.37 9.5 0.0 1.7 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CMS1 PF14617.6 KFR05092.1 - 0.23 10.8 2.0 0.59 9.4 0.0 2.3 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 KFR05092.1 - 0.28 10.4 0.0 0.28 10.4 0.0 2.2 3 0 0 3 3 3 0 ERCC3/RAD25/XPB C-terminal helicase LIM PF00412.22 KFR05093.1 - 9.2e-42 141.1 33.3 2.6e-15 56.4 6.5 3.3 3 0 0 3 3 3 3 LIM domain PDZ PF00595.24 KFR05093.1 - 6.6e-14 52.0 0.0 1.1e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFR05093.1 - 1.5e-05 24.8 0.0 3.6e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFR05093.1 - 0.0049 17.2 0.0 0.0092 16.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Cofilin_ADF PF00241.20 KFR05094.1 - 2.8e-10 40.0 0.0 5.7e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein WBP-1 PF11669.8 KFR05095.1 - 0.0041 17.7 12.4 0.0085 16.7 10.3 2.4 1 1 1 2 2 2 1 WW domain-binding protein 1 HemY_N PF07219.13 KFR05095.1 - 0.076 13.2 0.2 0.11 12.7 0.2 1.2 1 0 0 1 1 1 0 HemY protein N-terminus Herpes_UL73 PF03554.13 KFR05095.1 - 0.077 13.0 0.2 0.13 12.3 0.2 1.3 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein DUF4381 PF14316.6 KFR05095.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) SARAF PF06682.12 KFR05095.1 - 0.15 11.7 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis LST1 PF05083.13 KFR05095.1 - 0.18 12.1 1.1 0.3 11.4 0.4 1.7 2 0 0 2 2 2 0 LST-1 protein BatD PF13584.6 KFR05095.1 - 0.24 10.1 0.0 0.31 9.8 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance Pkinase PF00069.25 KFR05096.1 - 1.2e-67 228.0 0.0 1.9e-67 227.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR05096.1 - 2.9e-35 121.8 0.0 4.7e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 KFR05096.1 - 8.4e-21 74.4 0.6 3.2e-20 72.5 0.1 2.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain Pkinase_fungal PF17667.1 KFR05096.1 - 2.7e-05 23.1 0.0 5.2e-05 22.2 0.0 1.3 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KFR05096.1 - 7.3e-05 22.2 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like 7tm_1 PF00001.21 KFR05097.1 - 7.1e-70 235.3 5.7 8.7e-70 235.0 5.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR05097.1 - 1e-07 31.6 2.7 0.0041 16.5 0.1 2.4 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFR05097.1 - 6.1e-05 22.9 0.4 0.0003 20.6 0.9 1.9 2 0 0 2 2 2 1 Olfactory receptor Na_Pi_cotrans PF02690.15 KFR05098.1 - 7.2e-41 139.5 23.8 1.6e-25 89.9 6.0 2.9 2 1 0 2 2 2 2 Na+/Pi-cotransporter DUF2207 PF09972.9 KFR05098.1 - 6.7 5.3 7.2 96 1.5 7.2 2.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) RBD PF02196.15 KFR05099.1 - 1.1e-28 99.0 0.2 3.4e-22 78.3 0.0 2.4 2 0 0 2 2 2 2 Raf-like Ras-binding domain RGS PF00615.19 KFR05099.1 - 7e-27 94.0 2.4 1.3e-26 93.1 2.4 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain SopA PF13981.6 KFR05099.1 - 0.027 14.9 1.8 0.057 13.9 0.1 2.2 2 1 0 3 3 3 0 SopA-like central domain Bclx_interact PF08945.10 KFR05099.1 - 0.039 13.7 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain RGS12_us1 PF16613.5 KFR05099.1 - 0.071 13.4 0.8 0.071 13.4 0.8 2.8 2 1 1 3 3 3 0 Unstructured region of RGS12 Arf PF00025.21 KFR05100.1 - 1.6e-67 226.4 0.0 1.7e-67 226.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFR05100.1 - 9.1e-14 51.7 0.0 1.2e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFR05100.1 - 4.7e-13 48.9 0.0 5.6e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KFR05100.1 - 7e-13 48.5 0.0 8.1e-13 48.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KFR05100.1 - 9.6e-10 38.2 0.0 1.2e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KFR05100.1 - 1.5e-09 37.5 0.0 1.4e-05 24.4 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KFR05100.1 - 6e-09 36.0 0.0 8.5e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFR05100.1 - 4.9e-05 23.0 0.0 0.0066 16.0 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 KFR05100.1 - 0.0016 19.0 0.0 0.0038 17.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KFR05100.1 - 0.0071 16.3 0.1 4 7.3 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 KFR05100.1 - 0.0089 15.8 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KFR05100.1 - 0.03 13.9 0.0 7.4 6.1 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 KFR05100.1 - 0.041 13.4 0.0 0.11 12.1 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_28 PF13521.6 KFR05100.1 - 0.087 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFR05100.1 - 0.089 13.1 0.0 0.23 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KFR05100.1 - 0.14 12.2 0.0 0.29 11.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain Lectin_leg-like PF03388.13 KFR05101.1 - 1e-91 306.4 0.0 1.2e-91 306.2 0.0 1.0 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 KFR05101.1 - 2.4e-07 31.0 0.0 3.5e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial lectin UL42 PF17638.2 KFR05101.1 - 0.043 13.8 0.0 0.076 13.0 0.0 1.3 1 0 0 1 1 1 0 HCMV UL42 Glyco_transf_7C PF02709.14 KFR05102.1 - 5.1e-27 93.4 0.2 9.5e-27 92.5 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 KFR05102.1 - 6.4e-22 77.6 0.0 9.7e-22 77.1 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.9 KFR05102.1 - 0.12 11.8 0.0 3.1 7.2 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Bromodomain PF00439.25 KFR05103.1 - 1.7e-40 136.9 0.3 1.6e-20 72.9 0.1 2.8 2 0 0 2 2 2 2 Bromodomain HMW1C_N PF18071.1 KFR05103.1 - 0.04 13.7 5.4 0.13 12.1 0.1 2.7 3 0 0 3 3 3 0 HMW1C N-terminal TSC22 PF01166.18 KFR05103.1 - 0.11 12.8 2.3 0.3 11.4 2.3 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family Chal_sti_synt_N PF00195.19 KFR05103.1 - 0.16 11.4 0.1 0.31 10.4 0.1 1.4 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF2209 PF09974.9 KFR05103.1 - 0.61 10.4 3.3 2.5 8.5 3.3 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) EMC3_TMCO1 PF01956.16 KFR05103.1 - 1.5 8.6 4.7 5 6.8 4.7 1.9 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Kinesin PF00225.23 KFR05104.1 - 6.7e-103 344.1 0.2 6.7e-103 344.1 0.2 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFR05104.1 - 9.2e-19 67.8 1.0 3e-16 59.7 0.0 3.0 3 0 0 3 3 3 2 Microtubule binding MscS_porin PF12795.7 KFR05104.1 - 0.0091 15.6 21.3 0.0091 15.6 21.3 3.6 3 1 1 4 4 4 2 Mechanosensitive ion channel porin domain HSP70 PF00012.20 KFR05104.1 - 0.51 8.5 9.9 0.97 7.5 9.9 1.5 1 0 0 1 1 1 0 Hsp70 protein Mtc PF03820.17 KFR05105.1 - 1.8e-154 513.4 0.3 2.1e-154 513.2 0.3 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier 7tm_1 PF00001.21 KFR05106.1 - 9.7e-72 241.4 19.6 1.2e-71 241.1 19.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR05106.1 - 3e-09 36.6 18.0 5.3e-09 35.8 18.0 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFR05106.1 - 2.3e-07 30.7 15.5 2.3e-07 30.7 15.5 2.3 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF621 PF04789.15 KFR05106.1 - 0.097 11.8 18.1 0.046 12.9 14.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF621) Homeodomain PF00046.29 KFR05107.1 - 3.3e-22 78.1 5.2 4.8e-22 77.6 5.2 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFR05107.1 - 0.049 13.5 0.4 0.11 12.4 0.4 1.6 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.8 KFR05107.1 - 0.13 11.8 0.5 0.63 9.6 0.1 2.0 1 1 1 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Calcyon PF06387.11 KFR05108.1 - 7.6e-89 296.5 0.1 8.6e-89 296.3 0.1 1.0 1 0 0 1 1 1 1 D1 dopamine receptor-interacting protein (calcyon) NB PF04159.13 KFR05108.1 - 0.16 12.0 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 NB glycoprotein COMPASS-Shg1 PF05205.12 KFR05109.1 - 8.8e-20 71.3 0.0 1e-19 71.1 0.0 1.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 Stanniocalcin PF03298.13 KFR05110.1 - 7.8e-84 280.0 14.0 9.5e-84 279.7 14.0 1.1 1 0 0 1 1 1 1 Stanniocalcin family Homeodomain PF00046.29 KFR05111.1 - 2.9e-20 71.9 4.3 7e-20 70.6 4.3 1.7 1 0 0 1 1 1 1 Homeodomain Sin3a_C PF16879.5 KFR05111.1 - 0.012 15.4 0.8 0.017 14.9 0.8 1.2 1 0 0 1 1 1 0 C-terminal domain of Sin3a protein Homez PF11569.8 KFR05111.1 - 0.058 12.9 0.4 0.19 11.2 0.3 1.9 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Sec20 PF03908.13 KFR05112.1 - 1.1e-33 115.0 3.3 2e-33 114.2 3.3 1.4 1 0 0 1 1 1 1 Sec20 DUF2777 PF10949.8 KFR05112.1 - 0.0035 17.0 1.4 0.0051 16.5 0.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2777) DUF3490 PF11995.8 KFR05112.1 - 6.5 6.5 9.7 3.4 7.5 6.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3490) bZIP_1 PF00170.21 KFR05113.1 - 0.0031 17.6 2.4 0.0031 17.6 2.4 2.7 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 KFR05113.1 - 0.017 15.2 2.3 0.017 15.2 2.3 2.0 2 0 0 2 2 2 0 Basic region leucine zipper Ribosomal_L26 PF16906.5 KFR05114.1 - 9.1e-44 147.8 5.8 1.2e-43 147.4 5.8 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KFR05114.1 - 6.9e-08 32.2 5.9 2.2e-07 30.6 5.9 2.0 1 1 0 1 1 1 1 KOW motif BLYB PF05289.11 KFR05114.1 - 0.033 14.4 1.9 0.055 13.7 1.9 1.4 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein COPIIcoated_ERV PF07970.12 KFR05115.1 - 8.7e-37 127.1 0.1 1.5e-36 126.4 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KFR05115.1 - 7.9e-36 122.3 0.0 7.9e-36 122.3 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Neuralized PF07177.12 KFR05116.1 - 1.2e-88 294.8 0.0 1.5e-44 151.6 0.0 2.6 3 0 0 3 3 3 2 Neuralized zf-C3HC4_3 PF13920.6 KFR05116.1 - 5e-13 48.7 13.3 1.2e-12 47.4 13.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFR05116.1 - 2.6e-05 24.0 12.5 6.2e-05 22.8 12.5 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFR05116.1 - 0.016 15.1 13.9 0.04 13.9 13.9 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFR05116.1 - 0.12 12.3 15.4 0.26 11.2 15.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SH3_1 PF00018.28 KFR05117.1 - 1.6e-39 133.3 14.5 1.6e-13 50.0 0.3 4.4 4 0 0 4 4 4 4 SH3 domain SH3_9 PF14604.6 KFR05117.1 - 1.6e-34 117.5 9.2 6.9e-13 48.2 0.1 4.7 5 0 0 5 5 5 4 Variant SH3 domain SH3_2 PF07653.17 KFR05117.1 - 4.1e-31 106.4 4.6 2.6e-09 36.6 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.11 KFR05117.1 - 4.2e-12 46.2 14.8 5.1e-05 23.5 0.3 4.6 5 0 0 5 5 5 4 Bacterial SH3 domain PX PF00787.24 KFR05117.1 - 1.8e-06 27.9 2.8 3.1e-06 27.1 0.1 2.4 2 0 0 2 2 2 1 PX domain UBD PF16455.5 KFR05118.1 - 4.4e-39 132.9 0.0 6.1e-39 132.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 KFR05118.1 - 3.2e-14 52.4 0.0 5.1e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KFR05118.1 - 6.1e-06 26.0 0.0 8.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TPR_12 PF13424.6 KFR05119.1 - 3.3e-13 49.7 42.2 6.8e-06 26.3 2.4 7.5 6 1 1 7 7 7 5 Tetratricopeptide repeat SH3_2 PF07653.17 KFR05119.1 - 7.1e-10 38.4 0.1 7.9e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KFR05119.1 - 1.2e-08 34.4 0.4 0.0011 18.5 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KFR05119.1 - 1.1e-07 31.6 0.2 0.011 15.6 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain TPR_1 PF00515.28 KFR05119.1 - 3.9e-07 29.6 27.8 0.0011 18.7 0.0 9.5 9 1 1 10 10 10 2 Tetratricopeptide repeat SNAP PF14938.6 KFR05119.1 - 5.2e-07 29.4 1.1 1.6e-05 24.5 0.4 2.9 3 0 0 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_8 PF13181.6 KFR05119.1 - 0.0002 21.3 31.3 1.8 9.0 0.3 10.7 11 1 1 12 12 12 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFR05119.1 - 0.00031 20.6 37.1 0.035 14.2 0.1 10.2 10 1 1 11 11 11 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFR05119.1 - 0.1 12.6 22.3 3.3 8.0 0.1 8.7 9 1 1 10 10 10 0 Tetratricopeptide repeat PH PF00169.29 KFR05120.1 - 3.1e-18 66.2 0.0 1e-07 32.4 0.0 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KFR05120.1 - 0.00011 22.6 1.4 0.065 13.7 0.0 3.5 2 1 0 2 2 2 1 Pleckstrin homology domain Sharpin_PH PF16764.5 KFR05120.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 Sharpin PH domain Macoilin PF09726.9 KFR05120.1 - 0.022 13.4 4.8 0.034 12.7 4.8 1.2 1 0 0 1 1 1 0 Macoilin family PH_9 PF15410.6 KFR05120.1 - 0.75 10.2 2.4 32 4.9 0.0 3.6 3 2 0 3 3 3 0 Pleckstrin homology domain Fib_alpha PF08702.10 KFR05120.1 - 1 9.6 4.0 2.4 8.4 4.0 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 KFR05120.1 - 7.5 5.3 12.5 12 4.6 12.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein GrpE PF01025.19 KFR05121.1 - 2.1e-42 144.6 0.0 2.5e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 GrpE DUF2408 PF10303.9 KFR05121.1 - 0.008 16.8 0.2 0.011 16.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) CLZ PF16526.5 KFR05121.1 - 0.035 14.5 0.9 0.44 10.9 0.1 2.1 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Laminin_I PF06008.14 KFR05121.1 - 0.052 13.2 0.1 0.066 12.9 0.1 1.2 1 0 0 1 1 1 0 Laminin Domain I DUF4525 PF15027.6 KFR05121.1 - 0.14 11.9 0.2 0.22 11.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) Prenylcys_lyase PF07156.14 KFR05122.1 - 5.9e-150 499.4 0.0 7.1e-150 499.1 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 KFR05122.1 - 5.6e-07 29.2 0.0 1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase IL17 PF06083.11 KFR05123.1 - 7e-30 103.3 1.6 1.1e-29 102.7 1.6 1.3 1 0 0 1 1 1 1 Interleukin-17 MRI PF15325.6 KFR05123.1 - 0.18 12.9 0.0 0.29 12.2 0.0 1.3 1 0 0 1 1 1 0 Modulator of retrovirus infection Pkinase PF00069.25 KFR05124.1 - 4.4e-19 68.9 0.0 5.6e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KFR05124.1 - 1.8e-10 40.2 0.1 1.8e-10 40.2 0.1 1.4 2 0 0 2 2 2 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KFR05124.1 - 1.2e-09 37.8 0.0 1.4e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KFR05124.1 - 0.017 14.1 0.1 0.028 13.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KFR05124.1 - 0.071 12.4 1.1 0.13 11.6 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RhoGEF PF00621.20 KFR05125.1 - 2.2e-34 119.3 0.9 3.7e-34 118.5 0.9 1.4 1 0 0 1 1 1 1 RhoGEF domain SH3_2 PF07653.17 KFR05125.1 - 8.3e-13 47.8 0.0 1.3e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 KFR05125.1 - 5.8e-10 38.9 0.0 2e-07 30.8 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KFR05125.1 - 2.2e-07 30.4 0.0 1.9e-05 24.2 0.0 2.5 2 0 0 2 2 2 1 SH3 domain SH3_3 PF08239.11 KFR05125.1 - 2.8e-05 24.3 0.1 0.00045 20.4 0.0 2.5 3 0 0 3 3 3 1 Bacterial SH3 domain BAR PF03114.18 KFR05125.1 - 0.00026 20.7 0.7 0.016 14.9 0.0 2.7 3 0 0 3 3 3 1 BAR domain DUF4530 PF15039.6 KFR05125.1 - 0.041 14.0 0.1 0.13 12.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) PaREP1 PF05942.11 KFR05125.1 - 0.1 12.6 1.1 0.29 11.1 1.1 1.7 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family UvrB PF12344.8 KFR05125.1 - 1.8 8.5 3.6 1 9.3 1.0 1.9 2 0 0 2 2 2 0 Ultra-violet resistance protein B zf-B_box PF00643.24 KFR05126.1 - 1.4e-07 31.5 12.2 1.4e-07 31.5 12.2 3.6 3 1 1 4 4 4 3 B-box zinc finger zf-B_box PF00643.24 KFR05127.1 - 4.9e-07 29.8 5.1 4.9e-07 29.8 5.1 2.8 3 0 0 3 3 3 2 B-box zinc finger zf-UBP_var PF17807.1 KFR05127.1 - 0.058 13.2 0.4 0.058 13.2 0.4 2.2 2 0 0 2 2 2 0 Variant UBP zinc finger Sulfate_transp PF00916.20 KFR05128.1 - 3.7e-131 437.4 18.0 5.7e-131 436.8 18.0 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFR05128.1 - 2.6e-29 101.2 0.0 4.6e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain 7tm_1 PF00001.21 KFR05129.1 - 1.4e-67 227.8 15.0 1.8e-67 227.4 15.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2304 PF10066.9 KFR05129.1 - 0.97 9.7 6.8 13 6.1 1.4 3.1 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) F-box PF00646.33 KFR05130.1 - 0.0002 21.2 0.1 0.00058 19.7 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFR05130.1 - 0.0024 17.7 0.3 0.0064 16.4 0.3 1.7 1 0 0 1 1 1 1 F-box-like IL12p40_C PF10420.9 KFR05131.1 - 2.2e-23 82.6 2.6 3.4e-23 81.9 1.3 2.0 2 0 0 2 2 2 1 Cytokine interleukin-12p40 C-terminus Ig_2 PF13895.6 KFR05131.1 - 1.4e-05 25.3 1.7 0.00039 20.7 0.0 3.1 2 1 0 3 3 3 1 Immunoglobulin domain Ig_5 PF16681.5 KFR05131.1 - 0.00043 20.6 0.2 0.0046 17.3 0.0 2.5 2 1 1 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_3 PF13927.6 KFR05131.1 - 0.0016 19.0 4.7 0.014 15.9 0.1 3.3 3 0 0 3 3 3 1 Immunoglobulin domain Ig_4 PF16680.5 KFR05131.1 - 0.0069 16.6 0.0 0.28 11.5 0.0 2.6 2 0 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain LPD29 PF18847.1 KFR05131.1 - 0.034 15.1 0.7 0.14 13.1 0.1 2.3 3 0 0 3 3 3 0 Large polyvalent protein associated domain 29 Ig_6 PF18452.1 KFR05131.1 - 0.04 13.5 0.1 13 5.5 0.1 2.5 2 0 0 2 2 2 0 Immunoglobulin domain ig PF00047.25 KFR05131.1 - 0.055 13.6 8.3 0.16 12.2 0.2 4.3 3 2 1 4 4 4 0 Immunoglobulin domain DnaJ_C PF01556.18 KFR05149.1 - 2.4e-43 147.7 0.5 3.4e-43 147.3 0.5 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFR05149.1 - 7.8e-26 90.0 2.7 1.4e-25 89.1 2.7 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KFR05149.1 - 5.6e-15 55.5 20.4 1e-14 54.6 20.4 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KFR05149.1 - 0.045 13.7 11.9 0.62 10.1 4.5 2.7 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KFR05149.1 - 0.082 12.9 7.5 1.1 9.4 0.7 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA I-set PF07679.16 KFR05159.1 - 2.2e-107 351.4 0.0 3.1e-16 59.2 0.0 11.0 11 0 0 11 11 10 9 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR05159.1 - 3.2e-106 348.1 15.3 4.2e-14 52.9 0.1 11.3 11 0 0 11 11 11 10 Immunoglobulin domain Ig_2 PF13895.6 KFR05159.1 - 1.6e-78 259.1 8.4 1.6e-09 38.0 0.1 11.0 10 1 0 10 10 10 10 Immunoglobulin domain ig PF00047.25 KFR05159.1 - 7.5e-68 224.7 1.8 2.6e-12 46.7 0.0 10.4 10 0 0 10 10 10 8 Immunoglobulin domain fn3 PF00041.21 KFR05159.1 - 4.3e-63 209.6 7.5 7.7e-14 51.8 0.0 7.4 7 1 0 7 7 6 6 Fibronectin type III domain V-set PF07686.17 KFR05159.1 - 1.3e-28 99.3 11.0 0.0053 16.9 0.1 14.2 10 5 3 13 13 13 6 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFR05159.1 - 3.4e-17 62.3 3.0 0.095 12.8 0.0 9.0 9 0 0 9 9 9 4 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFR05159.1 - 2.8e-16 58.8 0.1 0.052 13.1 0.0 6.6 6 0 0 6 6 6 4 Immunoglobulin domain Ig_5 PF16681.5 KFR05159.1 - 1.9e-13 50.6 0.0 1.3 9.5 0.0 8.4 8 1 0 8 8 8 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 KFR05159.1 - 1.5e-09 38.1 0.0 0.013 15.8 0.0 6.6 6 0 0 6 6 6 1 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 KFR05159.1 - 3.8e-08 33.3 0.3 0.44 10.6 0.0 6.7 8 0 0 8 8 8 1 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 KFR05159.1 - 1.2e-07 31.8 0.0 13 6.1 0.0 7.6 8 0 0 8 8 7 0 T-cell surface glycoprotein CD3 delta chain V-set_CD47 PF08204.11 KFR05159.1 - 1.2e-06 28.6 0.0 0.0093 15.9 0.0 4.8 4 0 0 4 4 4 1 CD47 immunoglobulin-like domain Receptor_2B4 PF11465.8 KFR05159.1 - 2.1e-06 27.9 0.4 0.99 9.6 0.0 5.5 6 0 0 6 6 5 2 Natural killer cell receptor 2B4 Pur_ac_phosph_N PF16656.5 KFR05159.1 - 0.0002 21.9 7.2 2.1 9.0 0.0 6.8 6 1 0 6 6 6 1 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.5 KFR05159.1 - 0.0027 17.8 0.0 0.056 13.6 0.0 3.0 3 0 0 3 3 3 1 Fibronectin type III domain ChitinaseA_N PF08329.10 KFR05159.1 - 0.017 14.8 0.0 0.06 13.0 0.0 1.9 1 0 0 1 1 1 0 Chitinase A, N-terminal domain ATP1G1_PLM_MAT8 PF02038.16 KFR05160.1 - 3.6e-26 90.3 0.0 4.4e-26 90.1 0.0 1.1 1 0 0 1 1 1 1 ATP1G1/PLM/MAT8 family EphA2_TM PF14575.6 KFR05160.1 - 0.12 13.3 0.0 0.17 12.8 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Tissue_fac PF01108.17 KFR05161.1 - 5.6e-23 80.8 0.0 1e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.10 KFR05161.1 - 1.1e-06 28.9 0.0 2.3e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.21 KFR05161.1 - 1.1e-05 25.7 1.4 0.026 14.9 0.1 2.5 2 0 0 2 2 2 2 Fibronectin type III domain Trypsin PF00089.26 KFR05162.1 - 2.6e-72 243.2 0.3 3.1e-72 243.0 0.3 1.1 1 0 0 1 1 1 1 Trypsin SRCR_2 PF15494.6 KFR05162.1 - 5.2e-17 62.2 0.1 1.1e-16 61.1 0.1 1.6 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Trypsin_2 PF13365.6 KFR05162.1 - 3e-10 41.2 0.0 1.5e-09 38.9 0.0 1.9 2 0 0 2 2 2 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFR05162.1 - 1.1e-05 25.7 0.0 2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Hepsin-SRCR PF09272.10 KFR05162.1 - 1.5e-05 25.5 1.8 0.00017 22.1 1.8 2.2 1 1 0 1 1 1 1 Hepsin, SRCR domain SRCR PF00530.18 KFR05162.1 - 9.3e-05 22.9 0.0 0.00026 21.5 0.0 1.8 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain V-set PF07686.17 KFR05163.1 - 8.3e-11 42.0 0.1 1.3e-10 41.5 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFR05163.1 - 5.4e-09 36.5 0.1 9.8e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFR05163.1 - 8.6e-07 28.9 0.3 2.8e-06 27.3 0.1 2.0 2 1 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFR05163.1 - 7.6e-06 26.2 0.2 0.00017 21.8 0.2 2.1 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFR05163.1 - 2.2e-05 24.5 0.2 5.8e-05 23.2 0.2 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Glycophorin_A PF01102.18 KFR05163.1 - 0.0033 17.6 0.1 0.0052 17.0 0.1 1.3 1 0 0 1 1 1 1 Glycophorin A Izumo-Ig PF16706.5 KFR05163.1 - 0.0041 17.2 0.1 0.013 15.5 0.0 1.8 1 1 1 2 2 2 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFR05163.1 - 0.097 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain Collectrin PF16959.5 KFR05163.1 - 0.21 11.4 2.6 0.79 9.5 1.8 2.0 1 1 1 2 2 2 0 Renal amino acid transporter V-set PF07686.17 KFR05164.1 - 2.1e-21 76.1 0.3 3.7e-21 75.3 0.3 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFR05164.1 - 6.4e-07 29.5 0.7 6.4e-07 29.5 0.7 2.1 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFR05164.1 - 1e-06 28.7 0.0 2.8e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR05164.1 - 9.1e-05 23.0 0.7 0.00036 21.1 0.7 2.0 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFR05164.1 - 0.0003 21.0 3.2 0.0018 18.6 3.2 2.0 1 1 0 1 1 1 1 Immunoglobulin domain EphA2_TM PF14575.6 KFR05164.1 - 0.00077 20.3 0.0 0.0015 19.4 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 KFR05164.1 - 0.0024 17.8 0.0 0.018 14.9 0.0 2.3 2 0 0 2 2 2 1 Syndecan domain Adeno_E3_CR2 PF02439.15 KFR05164.1 - 0.0034 17.1 0.4 0.0063 16.2 0.4 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SKG6 PF08693.10 KFR05164.1 - 0.037 13.4 1.9 0.06 12.8 1.9 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Protocadherin PF08374.11 KFR05164.1 - 0.049 13.6 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 Protocadherin FAM176 PF14851.6 KFR05164.1 - 0.063 12.9 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 FAM176 family Herpes_gE PF02480.16 KFR05164.1 - 0.071 11.8 0.1 0.38 9.5 0.0 1.7 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E Vpu PF00558.19 KFR05164.1 - 0.08 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Vpu protein TMEM51 PF15345.6 KFR05164.1 - 0.15 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Ig_4 PF16680.5 KFR05164.1 - 0.75 10.1 8.1 2.8 8.3 0.0 2.9 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain V-set PF07686.17 KFR05165.1 - 9.9e-12 45.0 0.1 4.4e-11 42.9 0.1 1.8 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_6 PF18452.1 KFR05165.1 - 1.1e-05 24.9 0.0 4.2e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain DUF4381 PF14316.6 KFR05165.1 - 0.019 15.2 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Herpes_gE PF02480.16 KFR05165.1 - 0.031 13.0 0.0 0.12 11.1 0.0 1.6 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E stn_TNFRSF12A PF12191.8 KFR05165.1 - 0.035 14.3 0.1 0.056 13.7 0.1 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain ig PF00047.25 KFR05165.1 - 0.048 13.8 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.6 KFR05165.1 - 0.09 13.4 0.0 0.21 12.2 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KFR05167.1 - 1.7e-17 63.6 0.0 2.3e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFR05167.1 - 3.3e-07 30.4 0.0 7.2e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFR05167.1 - 6.5e-05 23.5 0.1 0.00014 22.4 0.1 1.5 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFR05167.1 - 0.018 15.4 0.1 0.41 11.0 0.1 2.2 1 1 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFR05167.1 - 0.025 14.7 0.0 0.06 13.4 0.0 1.6 1 1 0 1 1 1 0 Immunoglobulin I-set domain V-set PF07686.17 KFR05168.1 - 7.9e-23 80.7 0.0 1.2e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFR05168.1 - 1.2e-08 34.9 0.1 4.4e-08 33.2 0.0 1.9 2 1 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 KFR05168.1 - 1e-06 29.3 0.1 2e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFR05168.1 - 1.1e-06 28.6 0.0 2.7e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFR05168.1 - 9.9e-05 22.6 0.2 0.0029 17.9 0.2 2.3 1 1 0 1 1 1 1 Immunoglobulin domain TMEM154 PF15102.6 KFR05168.1 - 0.0039 17.1 0.2 0.0061 16.5 0.2 1.2 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 KFR05168.1 - 0.0062 17.4 0.1 0.0096 16.8 0.1 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 KFR05168.1 - 0.025 14.6 0.8 0.089 12.8 0.4 1.8 2 0 0 2 2 2 0 Protocadherin Ly49 PF08391.10 KFR05168.1 - 0.059 13.7 0.4 0.09 13.1 0.4 1.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Sarcoglycan_2 PF05510.13 KFR05168.1 - 0.082 11.7 0.1 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Orthoreo_P10 PF07204.11 KFR05168.1 - 0.098 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Vpu PF00558.19 KFR05168.1 - 0.11 12.2 0.3 0.11 12.2 0.3 1.6 2 0 0 2 2 2 0 Vpu protein Syndecan PF01034.20 KFR05168.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Shisa PF13908.6 KFR05168.1 - 0.18 12.0 0.3 0.26 11.5 0.3 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Ig_5 PF16681.5 KFR05169.1 - 1.8e-11 44.3 0.1 2.6e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFR05169.1 - 4.8e-07 30.0 0.2 8e-07 29.2 0.2 1.4 1 1 0 1 1 1 1 T-cell surface glycoprotein CD3 delta chain ITAM PF02189.15 KFR05169.1 - 0.0035 17.7 0.0 0.0062 16.9 0.0 1.4 1 0 0 1 1 1 1 Immunoreceptor tyrosine-based activation motif CHB_HEX_C_1 PF13290.6 KFR05169.1 - 0.11 12.6 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain Ig_4 PF16680.5 KFR05170.1 - 1.8e-25 89.0 0.1 2.8e-25 88.4 0.1 1.3 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFR05170.1 - 2.6e-11 43.8 0.1 4.4e-11 43.0 0.1 1.4 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain ITAM PF02189.15 KFR05170.1 - 2e-06 27.9 1.8 4.3e-06 26.8 1.8 1.6 1 0 0 1 1 1 1 Immunoreceptor tyrosine-based activation motif Ig_2 PF13895.6 KFR05170.1 - 0.00019 21.7 0.0 0.00041 20.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFR05170.1 - 0.00029 21.4 0.0 0.00077 20.0 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFR05170.1 - 0.00059 19.9 0.1 0.0053 16.8 0.1 2.3 1 1 0 1 1 1 1 Immunoglobulin I-set domain DAP10 PF07213.11 KFR05170.1 - 0.0027 17.6 0.2 0.0051 16.7 0.2 1.4 1 0 0 1 1 1 1 DAP10 membrane protein ig PF00047.25 KFR05170.1 - 0.095 12.9 0.4 1.6 9.0 0.4 2.2 1 1 0 1 1 1 0 Immunoglobulin domain Izumo-Ig PF16706.5 KFR05170.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.6 1 1 0 1 1 1 0 Izumo-like Immunoglobulin domain Zw10 PF06248.13 KFR05171.1 - 1.9e-182 607.6 13.5 2.8e-182 607.1 13.5 1.2 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Reovirus_M2 PF05993.12 KFR05171.1 - 0.064 11.3 0.0 0.1 10.7 0.0 1.2 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) DUF4363 PF14276.6 KFR05171.1 - 1.6 8.8 9.4 25 5.0 0.0 4.4 4 1 0 4 4 4 0 Domain of unknown function (DUF4363) 7tm_1 PF00001.21 KFR05172.1 - 2e-84 283.0 10.0 3.2e-84 282.4 10.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR05172.1 - 8.4e-18 64.7 21.3 1.3e-13 51.0 13.2 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 KFR05172.1 - 2.9e-05 23.6 23.9 0.0031 16.9 16.7 2.3 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srt PF10321.9 KFR05172.1 - 0.00012 21.2 17.8 0.023 13.7 1.7 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srt 7tm_4 PF13853.6 KFR05172.1 - 0.00034 20.4 11.6 0.00034 20.4 11.6 2.4 2 1 0 2 2 2 1 Olfactory receptor RAMP4 PF06624.12 KFR05172.1 - 0.025 14.6 0.1 1.4 9.0 0.0 2.7 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 RIFIN PF02009.16 KFR05172.1 - 0.052 13.4 0.4 0.052 13.4 0.4 1.8 2 0 0 2 2 2 0 Rifin CcmH PF03918.14 KFR05172.1 - 0.074 12.3 0.0 0.84 8.9 0.0 2.3 2 0 0 2 2 2 0 Cytochrome C biogenesis protein DUF3806 PF12713.7 KFR05172.1 - 0.1 12.4 1.1 6.9 6.5 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3806) Orf78 PF06024.12 KFR05172.1 - 0.26 11.6 7.8 2.3 8.5 0.6 3.7 3 1 0 3 3 3 0 Orf78 (ac78) Virul_fac_BrkB PF03631.15 KFR05172.1 - 0.55 9.8 12.4 0.051 13.2 1.1 2.9 3 0 0 3 3 3 0 Virulence factor BrkB Stevor PF17410.2 KFR05172.1 - 0.57 9.7 3.4 1.3 8.5 3.4 1.6 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF2207 PF09972.9 KFR05172.1 - 2 7.1 9.4 21 3.7 0.0 3.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) EphA2_TM PF14575.6 KFR05172.1 - 9.3 7.2 8.2 2.1 9.3 0.0 3.5 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Ank_2 PF12796.7 KFR05173.1 - 7.7e-106 346.9 21.6 4.9e-15 55.9 0.3 6.2 2 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 KFR05173.1 - 2.4e-76 249.1 6.2 5.2e-07 29.8 0.0 12.3 12 0 0 12 12 12 12 Ankyrin repeat Ank_3 PF13606.6 KFR05173.1 - 3.2e-68 217.6 10.7 2.9e-05 24.1 0.0 12.4 12 0 0 12 12 12 12 Ankyrin repeat Ank_4 PF13637.6 KFR05173.1 - 1.1e-64 214.0 8.4 8.3e-10 39.0 0.0 8.9 3 2 6 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFR05173.1 - 2.4e-53 177.5 7.4 7.6e-11 42.0 0.0 8.4 2 2 6 9 9 9 9 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 KFR05173.1 - 8.3e-46 156.4 0.1 1.5e-45 155.5 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR05173.1 - 3.5e-45 154.4 0.0 5.6e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PH_9 PF15410.6 KFR05173.1 - 0.82 10.1 4.0 46 4.4 0.0 3.5 3 1 1 4 4 4 0 Pleckstrin homology domain TPR_1 PF00515.28 KFR05174.1 - 2.3e-13 49.3 15.0 2.9e-06 26.9 1.8 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFR05174.1 - 3e-12 45.7 10.8 3e-06 26.9 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFR05174.1 - 3e-06 27.6 0.6 0.002 18.6 0.3 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFR05174.1 - 5e-06 26.3 10.1 5.3e-05 23.1 0.2 3.6 3 0 0 3 3 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFR05174.1 - 1e-05 25.7 4.7 3.3e-05 24.0 3.9 2.5 2 0 0 2 2 1 1 Anaphase-promoting complex, cyclosome, subunit 3 Arm PF00514.23 KFR05174.1 - 1.6e-05 24.7 7.4 3.2 7.9 0.0 5.8 6 0 0 6 6 5 1 Armadillo/beta-catenin-like repeat TPR_12 PF13424.6 KFR05174.1 - 1.9e-05 24.8 5.8 0.0045 17.3 1.4 3.4 1 1 1 2 2 2 2 Tetratricopeptide repeat HEAT PF02985.22 KFR05174.1 - 3.6e-05 23.6 2.1 2.4 8.7 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat Fis1_TPR_C PF14853.6 KFR05174.1 - 3.9e-05 23.6 1.2 0.045 13.8 0.1 3.0 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 KFR05174.1 - 5.8e-05 22.7 2.9 0.057 13.1 0.5 3.3 2 1 1 3 3 3 1 TPR repeat TPR_16 PF13432.6 KFR05174.1 - 0.00082 20.0 0.0 0.066 13.9 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFR05174.1 - 0.0012 19.5 0.1 1.1 10.3 0.0 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat HEAT_2 PF13646.6 KFR05174.1 - 0.0018 18.7 0.9 1.5 9.3 0.0 4.6 4 1 0 4 4 4 1 HEAT repeats TPR_6 PF13174.6 KFR05174.1 - 0.0018 18.8 0.4 0.057 14.1 0.0 3.6 2 0 0 2 2 2 1 Tetratricopeptide repeat HEAT_EZ PF13513.6 KFR05174.1 - 0.0028 18.1 3.0 4.6 7.9 0.1 4.7 5 0 0 5 5 5 1 HEAT-like repeat TPR_7 PF13176.6 KFR05174.1 - 0.0029 17.5 2.6 1.2 9.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3361 PF11841.8 KFR05174.1 - 0.0096 15.9 0.2 0.32 10.9 0.0 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF3361) Cnd1 PF12717.7 KFR05174.1 - 0.016 15.2 6.0 0.35 10.9 0.0 4.4 5 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 TPR_17 PF13431.6 KFR05174.1 - 0.43 11.1 5.8 0.63 10.6 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat RICTOR_M PF14666.6 KFR05174.1 - 0.55 10.0 2.9 1.4 8.7 0.2 3.1 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, middle domain U3_snoRNA_assoc PF08297.11 KFR05174.1 - 6 7.7 6.9 1.4 9.7 2.6 2.2 2 1 0 2 2 2 0 U3 snoRNA associated I-set PF07679.16 KFR05175.1 - 2.3e-76 251.9 6.5 2e-17 63.1 0.1 5.5 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR05175.1 - 1.5e-68 227.4 8.8 9.3e-16 58.2 0.4 6.2 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 KFR05175.1 - 2.4e-50 168.6 2.7 2.4e-10 40.5 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin domain Ig_2 PF13895.6 KFR05175.1 - 1.7e-41 140.4 2.8 1.7e-08 34.7 0.0 5.5 5 0 0 5 5 5 5 Immunoglobulin domain fn3 PF00041.21 KFR05175.1 - 9.1e-26 90.0 0.4 3.6e-13 49.7 0.1 3.0 2 0 0 2 2 2 2 Fibronectin type III domain V-set PF07686.17 KFR05175.1 - 5.8e-20 71.5 7.0 0.00017 21.8 0.0 7.6 5 4 0 5 5 5 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFR05175.1 - 5.1e-10 39.3 4.0 0.16 12.1 0.0 5.2 6 0 0 6 6 5 3 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFR05175.1 - 3.4e-09 36.6 0.1 0.28 11.3 0.0 5.0 5 0 0 5 5 5 2 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFR05175.1 - 4.2e-09 36.7 3.5 0.34 11.3 0.1 6.0 5 2 0 5 5 5 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFR05175.1 - 2.5e-08 34.1 3.3 1.9 8.8 0.2 6.4 5 2 0 5 5 5 2 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 KFR05175.1 - 1.1e-07 31.8 0.1 0.35 10.9 0.0 4.6 4 0 0 4 4 4 2 C17orf99 Ig domain C1-set PF07654.15 KFR05175.1 - 2.7e-07 30.9 5.7 0.019 15.3 0.0 5.4 5 0 0 5 5 5 1 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFR05175.1 - 9.2e-06 25.1 0.0 3.2 7.4 0.0 4.7 5 0 0 5 5 5 1 Immunoglobulin domain Receptor_2B4 PF11465.8 KFR05175.1 - 0.0017 18.5 0.5 2.5 8.4 0.0 4.2 4 0 0 4 4 4 1 Natural killer cell receptor 2B4 Collagen_bind_2 PF12904.7 KFR05175.1 - 0.072 13.1 0.2 1.6 8.8 0.1 2.8 2 0 0 2 2 2 0 Putative collagen-binding domain of a collagenase SspH PF08141.12 KFR05175.1 - 0.16 12.1 0.1 27 5.0 0.0 2.9 2 0 0 2 2 2 0 Small acid-soluble spore protein H family Pur_ac_phosph_N PF16656.5 KFR05175.1 - 0.21 12.2 0.1 0.21 12.2 0.1 4.2 5 2 0 5 5 3 0 Purple acid Phosphatase, N-terminal domain DUF503 PF04456.12 KFR05176.1 - 0.023 14.5 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF503) Reeler PF02014.16 KFR05176.1 - 0.079 13.7 0.0 0.081 13.7 0.0 1.1 1 0 0 1 1 1 0 Reeler domain PTPS PF01242.19 KFR05177.1 - 3e-32 111.1 0.0 3.6e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase RPE65 PF03055.15 KFR05178.1 - 5.5e-132 441.2 0.1 6.2e-132 441.1 0.1 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein TEX12 PF15219.6 KFR05179.1 - 4e-32 110.4 0.1 4.6e-32 110.2 0.1 1.0 1 0 0 1 1 1 1 Testis-expressed 12 FCH PF00611.23 KFR05179.1 - 0.03 14.6 0.1 0.045 14.0 0.1 1.3 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain IL1 PF00340.19 KFR05180.1 - 5.1e-10 39.1 0.3 7.2e-10 38.6 0.3 1.2 1 0 0 1 1 1 1 Interleukin-1 / 18 CybS PF05328.12 KFR05181.1 - 9e-23 80.4 0.9 1.1e-22 80.1 0.9 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit NKAP PF15692.5 KFR05182.1 - 4.7e-22 78.5 26.5 4.7e-22 78.5 26.5 5.0 2 1 3 5 5 5 1 NF-kappa-B-activating protein Macoilin PF09726.9 KFR05182.1 - 1.3 7.5 34.3 1.6 7.2 34.3 1.1 1 0 0 1 1 1 0 Macoilin family PIH1_CS PF18201.1 KFR05183.1 - 1.6e-13 50.9 0.4 3.3e-13 49.9 0.4 1.5 1 0 0 1 1 1 1 PIH1 CS-like domain PIH1 PF08190.12 KFR05183.1 - 1.2e-07 31.4 0.0 6.3e-07 29.0 0.0 2.0 1 1 0 1 1 1 1 PIH1 N-terminal domain ArsA_HSP20 PF17886.1 KFR05183.1 - 4.3e-06 26.2 0.1 9.5e-06 25.1 0.1 1.6 1 0 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 KFR05183.1 - 0.085 13.0 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Hsp20/alpha crystallin family 2-oxoacid_dh PF00198.23 KFR05184.1 - 1.4e-80 270.1 0.1 1.8e-80 269.8 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFR05184.1 - 1e-31 108.6 0.9 2.5e-15 56.1 0.1 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme E3_binding PF02817.17 KFR05184.1 - 5.3e-18 65.1 0.4 1.4e-17 63.7 0.4 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KFR05184.1 - 0.00018 21.3 0.0 1.1 9.1 0.0 2.9 2 0 0 2 2 2 2 Biotin-lipoyl like HSP20 PF00011.21 KFR05186.1 - 1.1e-19 70.4 0.1 1.6e-19 70.0 0.1 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Crystallin PF00525.18 KFR05186.1 - 4.8e-06 26.6 0.0 8.3e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal HSP20 PF00011.21 KFR05187.1 - 3.1e-27 94.7 0.1 3.7e-27 94.4 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Crystallin PF00525.18 KFR05187.1 - 1.8e-24 85.6 1.4 2.9e-24 85.0 1.4 1.3 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal ArsA_HSP20 PF17886.1 KFR05187.1 - 0.0023 17.4 0.0 0.0042 16.6 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF2431 PF10354.9 KFR05188.1 - 1.1e-30 107.1 0.0 2.1e-30 106.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) FDX-ACB PF03147.14 KFR05188.1 - 7.9e-17 61.5 0.0 1.4e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2d PF01409.20 KFR05188.1 - 0.00039 20.0 0.0 0.0011 18.6 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) LRR_8 PF13855.6 KFR05195.1 - 1.3e-50 169.0 64.5 1e-15 57.2 3.1 6.6 2 2 5 7 7 7 7 Leucine rich repeat LRR_5 PF13306.6 KFR05195.1 - 2.2e-18 66.4 0.0 2.7e-08 33.8 0.0 2.3 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFR05195.1 - 4.4e-16 58.7 48.6 2.1e-05 24.8 0.6 7.9 6 1 3 9 9 9 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFR05195.1 - 5.5e-06 26.2 36.0 7.5 7.5 0.1 11.0 10 2 0 10 10 10 5 Leucine Rich Repeat LRR_9 PF14580.6 KFR05195.1 - 5.7e-05 22.7 13.1 0.44 10.0 1.9 4.1 2 2 2 4 4 4 3 Leucine-rich repeat LRRNT PF01462.18 KFR05195.1 - 0.009 15.6 1.8 0.009 15.6 1.8 2.9 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain MCLC PF05934.11 KFR05195.1 - 0.25 10.0 0.1 0.38 9.4 0.1 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF3736 PF12540.8 KFR05196.1 - 0.14 12.2 0.0 0.16 12.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3736) FXMRP1_C_core PF12235.8 KFR05197.1 - 4.1e-44 150.6 10.1 4.1e-44 150.6 10.1 2.7 1 1 1 2 2 2 1 Fragile X-related 1 protein core C terminal FXMR_C2 PF16098.5 KFR05197.1 - 1.9e-37 127.6 8.3 1.9e-37 127.6 8.3 2.2 3 0 0 3 3 3 1 Fragile X-related mental retardation protein C-terminal region 2 KH_9 PF17904.1 KFR05197.1 - 2e-37 127.4 1.2 5.7e-37 126.0 1.2 1.8 1 0 0 1 1 1 1 FMRP KH0 domain Tudor_FRX1 PF18336.1 KFR05197.1 - 6.1e-19 67.7 2.3 6.1e-19 67.7 2.3 2.2 2 0 0 2 2 2 1 Fragile X mental retardation Tudor domain KH_1 PF00013.29 KFR05197.1 - 1.9e-17 62.9 0.5 2.1e-09 37.0 0.7 2.5 2 0 0 2 2 2 2 KH domain Agenet PF05641.12 KFR05197.1 - 1.6e-08 34.8 1.5 3.4e-06 27.4 0.5 2.9 3 0 0 3 3 3 1 Agenet domain KH_2 PF07650.17 KFR05197.1 - 0.00066 19.5 0.6 0.26 11.1 0.0 2.5 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 KFR05197.1 - 0.044 13.7 1.6 3 7.8 0.3 3.4 2 1 1 3 3 3 0 KH domain FXR_C3 PF16097.5 KFR05197.1 - 1.4 9.7 5.3 1.3 9.8 0.8 2.7 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 3 Sulfatase PF00884.23 KFR05198.1 - 2.6e-50 171.6 0.0 3.9e-50 171.0 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFR05198.1 - 6.1e-10 39.2 0.0 0.00021 21.0 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KFR05198.1 - 0.0031 16.2 0.0 0.019 13.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 KFR05198.1 - 0.062 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Tmemb_185A PF10269.9 KFR05199.1 - 4.9e-61 206.6 28.0 7e-61 206.1 28.0 1.2 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein ASCH PF04266.14 KFR05200.1 - 0.053 14.1 0.0 0.058 14.0 0.0 1.3 1 1 0 1 1 1 0 ASCH domain Lipoprotein_20 PF13942.6 KFR05200.1 - 0.092 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 YfhG lipoprotein Myotub-related PF06602.14 KFR05203.1 - 3e-149 496.8 0.0 4.2e-149 496.3 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 KFR05203.1 - 9.4e-20 70.6 0.0 2.2e-19 69.4 0.0 1.6 2 0 0 2 2 2 1 GRAM domain DSPc PF00782.20 KFR05203.1 - 0.0004 20.2 0.0 0.00079 19.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFR05203.1 - 0.00064 19.4 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase 3-PAP PF12578.8 KFR05203.1 - 0.0022 17.7 0.1 0.0051 16.5 0.1 1.7 1 0 0 1 1 1 1 Myotubularin-associated protein Y_phosphatase3 PF13350.6 KFR05203.1 - 0.016 15.2 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Myotub-related PF06602.14 KFR05204.1 - 1.1e-149 498.2 0.0 1.4e-149 497.9 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 KFR05204.1 - 5.5e-09 35.9 0.0 1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Y_phosphatase PF00102.27 KFR05204.1 - 0.00099 18.7 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFR05204.1 - 0.00099 18.9 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFR05204.1 - 0.0021 18.1 0.0 0.0035 17.4 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family 3-PAP PF12578.8 KFR05204.1 - 0.0044 16.8 0.3 0.013 15.2 0.1 1.9 2 0 0 2 2 2 1 Myotubularin-associated protein DUF4441 PF14536.6 KFR05204.1 - 0.18 12.0 1.5 0.42 10.8 1.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) Myb_CC_LHEQLE PF14379.6 KFR05204.1 - 0.36 10.6 3.5 11 5.8 0.9 2.5 2 0 0 2 2 2 0 MYB-CC type transfactor, LHEQLE motif CD99L2 PF12301.8 KFR05205.1 - 3.8e-47 160.7 1.1 4.2e-47 160.6 1.1 1.0 1 0 0 1 1 1 1 CD99 antigen like protein 2 ACT_7 PF13840.6 KFR05205.1 - 0.021 14.6 0.3 0.034 13.9 0.3 1.2 1 0 0 1 1 1 0 ACT domain DUF2953 PF11167.8 KFR05205.1 - 0.06 13.4 0.2 0.091 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) HMG_box_2 PF09011.10 KFR05206.1 - 2.8e-49 165.6 10.3 5.5e-30 103.8 7.3 2.3 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 KFR05206.1 - 8.8e-44 147.8 9.8 1e-27 96.3 0.1 2.5 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_5 PF14887.6 KFR05206.1 - 0.00054 19.9 11.4 0.11 12.5 1.2 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box 5 Ribosomal_60s PF00428.19 KFR05206.1 - 0.026 15.1 18.0 0.082 13.5 18.0 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein YABBY PF04690.13 KFR05206.1 - 0.76 10.3 6.5 0.21 12.1 0.8 2.5 1 1 2 3 3 3 0 YABBY protein 7tm_1 PF00001.21 KFR05207.1 - 4e-41 141.1 27.5 5e-41 140.8 27.5 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFR05207.1 - 2e-09 37.5 26.2 3.8e-09 36.5 26.2 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Git3 PF11710.8 KFR05207.1 - 7.5 6.3 25.6 3.4 7.4 16.4 2.2 1 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 VMA21 PF09446.10 KFR05208.1 - 4.5e-23 81.1 7.7 5e-23 81.0 7.7 1.0 1 0 0 1 1 1 1 VMA21-like domain PAS_11 PF14598.6 KFR05210.1 - 1.5e-21 76.7 0.0 2.5e-19 69.4 0.0 2.8 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 KFR05210.1 - 3.9e-20 71.9 0.1 3.4e-16 59.3 0.1 2.9 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 KFR05210.1 - 3.1e-11 43.2 0.0 4.9e-08 33.0 0.0 3.2 3 0 0 3 3 3 2 PAS fold HLH PF00010.26 KFR05210.1 - 9.2e-11 41.5 0.8 1.9e-10 40.6 0.8 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 KFR05210.1 - 0.0002 21.6 0.0 0.001 19.3 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 KFR05210.1 - 0.0079 16.4 0.0 0.77 10.0 0.0 3.0 3 0 0 3 3 3 1 PAS fold Meis_PKNOX_N PF16493.5 KFR05210.1 - 0.44 10.9 3.5 8.8 6.7 0.1 3.2 3 0 0 3 3 3 0 N-terminal of Homeobox Meis and PKNOX1 DDRGK PF09756.9 KFR05210.1 - 3.4 7.2 8.2 0.53 9.8 1.8 2.1 2 0 0 2 2 2 0 DDRGK domain zf-RING_2 PF13639.6 KFR05211.1 - 1.2e-11 44.7 7.4 2.2e-11 43.9 7.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFR05211.1 - 1.2e-08 35.1 5.6 2.9e-08 33.8 5.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KFR05211.1 - 4.1e-08 32.8 3.4 7.9e-08 31.9 3.4 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFR05211.1 - 4.5e-08 32.8 7.4 8.2e-08 32.0 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 KFR05211.1 - 2.6e-07 30.6 0.1 4.9e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 PA domain zf-C3HC4 PF00097.25 KFR05211.1 - 3.2e-07 30.1 7.9 5.8e-07 29.3 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFR05211.1 - 2.4e-06 27.4 8.4 4.3e-06 26.6 8.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFR05211.1 - 3.3e-05 23.8 5.0 6e-05 23.0 5.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFR05211.1 - 0.00023 20.9 7.1 0.00038 20.2 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFR05211.1 - 0.00056 19.7 9.2 0.001 18.9 9.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF1251 PF06856.11 KFR05211.1 - 0.005 16.5 0.1 0.015 15.0 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1251) zf-ANAPC11 PF12861.7 KFR05211.1 - 0.0062 16.6 3.1 0.013 15.5 3.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_16 PF17034.5 KFR05211.1 - 0.02 15.1 2.1 0.051 13.8 2.1 1.6 1 0 0 1 1 1 0 Zinc-ribbon like family zf-C3H2C3 PF17122.5 KFR05211.1 - 0.035 14.1 2.6 0.085 12.9 2.6 1.7 1 0 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 KFR05211.1 - 0.061 13.0 6.6 0.14 11.8 6.6 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type LapA_dom PF06305.11 KFR05211.1 - 0.11 12.4 0.3 0.19 11.6 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain PHD PF00628.29 KFR05211.1 - 0.43 10.5 8.0 0.92 9.5 8.0 1.6 1 0 0 1 1 1 0 PHD-finger DUF5521 PF17659.1 KFR05212.1 - 9.6e-232 771.4 0.4 1.2e-231 771.1 0.4 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5521) Acyltransf_C PF16076.5 KFR05212.1 - 0.0026 17.8 0.3 0.059 13.5 0.3 2.8 1 1 0 1 1 1 1 Acyltransferase C-terminus DUF5088 PF17008.5 KFR05212.1 - 0.0088 15.8 0.0 0.018 14.7 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF5088) tRNA_anti-codon PF01336.25 KFR05212.1 - 0.03 14.3 0.0 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Eryth_link_C PF16915.5 KFR05212.1 - 0.069 13.2 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Annelid erythrocruorin linker subunit C-terminus Pkinase PF00069.25 KFR05213.1 - 1.2e-54 185.5 0.0 2.1e-54 184.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain CNH PF00780.22 KFR05213.1 - 6.3e-54 183.4 0.0 1.2e-53 182.5 0.0 1.5 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.17 KFR05213.1 - 6.2e-41 140.4 0.0 1e-40 139.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR05213.1 - 0.00096 18.5 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFR05213.1 - 0.32 10.9 0.1 0.32 10.9 0.1 2.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family TIR PF01582.20 KFR05214.1 - 7.5e-31 107.3 0.1 2e-30 105.9 0.1 1.7 1 0 0 1 1 1 1 TIR domain Ig_2 PF13895.6 KFR05214.1 - 1.3e-21 76.7 0.0 3.8e-08 33.6 0.1 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Ig_6 PF18452.1 KFR05214.1 - 2.1e-21 75.2 0.0 5.2e-15 54.7 0.1 3.4 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFR05214.1 - 6.3e-21 74.2 0.1 1e-05 25.5 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR05214.1 - 9.3e-20 71.0 0.0 5.9e-06 26.8 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFR05214.1 - 2.5e-17 62.8 0.1 3e-05 24.1 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFR05214.1 - 9.9e-11 41.8 0.3 0.2 11.8 0.0 5.2 3 3 1 4 4 4 3 Immunoglobulin V-set domain TIR_2 PF13676.6 KFR05214.1 - 1.3e-06 29.0 0.0 2.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 TIR domain Izumo-Ig PF16706.5 KFR05214.1 - 5.3e-05 23.2 0.2 0.17 12.0 0.0 3.5 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain V-set_CD47 PF08204.11 KFR05214.1 - 0.0015 18.5 4.0 0.083 12.9 0.1 3.3 4 0 0 4 4 4 1 CD47 immunoglobulin-like domain Herpes_gE PF02480.16 KFR05214.1 - 0.023 13.5 0.0 0.81 8.4 0.0 2.6 2 1 0 2 2 2 0 Alphaherpesvirus glycoprotein E FAM199X PF15814.5 KFR05215.1 - 9.3e-206 682.2 21.9 1e-205 682.0 21.9 1.0 1 0 0 1 1 1 1 Protein family FAM199X Macoilin PF09726.9 KFR05215.1 - 0.053 12.1 11.7 0.064 11.8 11.7 1.1 1 0 0 1 1 1 0 Macoilin family COMM_domain PF07258.14 KFR05216.1 - 6.1e-18 64.7 0.6 2.1e-17 63.0 0.1 2.0 2 0 0 2 2 2 1 COMM domain HOCHOB PF17943.1 KFR05216.1 - 0.096 13.4 0.0 0.72 10.6 0.0 2.1 2 0 0 2 2 2 0 Homeobox-cysteine loop-homeobox LON_substr_bdg PF02190.16 KFR05217.1 - 9e-21 74.7 0.0 1.1e-20 74.4 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KFR05217.1 - 9.3e-09 35.0 9.2 2.9e-08 33.4 9.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFR05217.1 - 1.9e-06 27.7 8.2 5.1e-06 26.2 8.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFR05217.1 - 3.1e-06 26.9 8.5 3.1e-06 26.9 8.5 2.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFR05217.1 - 3.5e-06 26.9 7.6 1e-05 25.3 7.6 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFR05217.1 - 3.7e-06 27.2 9.0 3.7e-06 27.2 9.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KFR05217.1 - 1.1e-05 25.5 5.7 3.4e-05 23.9 5.7 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KFR05217.1 - 6.6e-05 22.8 8.3 6.6e-05 22.8 8.3 2.7 2 1 1 3 3 3 1 RING-type zinc-finger zf-rbx1 PF12678.7 KFR05217.1 - 0.00011 22.4 7.0 0.00036 20.7 7.0 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFR05217.1 - 0.00032 20.5 8.7 0.00032 20.5 8.7 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KFR05217.1 - 0.0066 16.2 5.2 0.0066 16.2 5.2 2.0 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Mito_carr PF00153.27 KFR05220.1 - 2e-57 191.1 0.3 3.2e-25 87.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFR05220.1 - 0.0022 17.2 0.2 0.0081 15.4 0.0 2.0 2 1 1 3 3 3 1 Gammaproteobacterial serine protease Mito_carr PF00153.27 KFR05221.1 - 1.7e-54 181.7 2.1 3.3e-23 81.4 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 KFR05221.1 - 0.038 13.2 0.1 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 Fuseless GFA PF04828.14 KFR05222.1 - 0.15 12.4 0.2 3.1 8.2 0.0 2.3 1 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF4410 PF14366.6 KFR05222.1 - 0.21 11.5 3.0 0.44 10.5 3.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4410) UQ_con PF00179.26 KFR05223.1 - 1e-40 138.6 0.3 1.4e-40 138.2 0.3 1.3 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFR05223.1 - 5.4e-05 23.5 0.1 6.8e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KFR05223.1 - 0.0014 18.3 0.0 0.0018 18.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KFR05223.1 - 0.0086 15.9 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 UEV domain DUF5487 PF17589.2 KFR05223.1 - 0.023 14.9 0.0 0.036 14.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5487) UFC1 PF08694.11 KFR05223.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Ribosomal_L39 PF00832.20 KFR05224.1 - 3.6e-24 84.1 11.0 4.1e-24 83.9 11.0 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Smg4_UPF3 PF03467.15 KFR05225.1 - 3.9e-40 137.7 7.2 3.9e-40 137.7 7.2 5.2 1 1 2 3 3 3 1 Smg-4/UPF3 family Nkap_C PF06047.11 KFR05226.1 - 5.2e-50 167.8 2.0 5.2e-50 167.8 2.0 2.9 2 1 1 3 3 3 1 NF-kappa-B-activating protein C-terminal domain NKAP PF15692.5 KFR05226.1 - 1e-13 51.8 15.1 1e-13 51.8 15.1 4.0 2 1 2 4 4 4 1 NF-kappa-B-activating protein SOBP PF15279.6 KFR05226.1 - 0.23 12.0 15.8 0.42 11.2 15.8 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Ndc1_Nup PF09531.10 KFR05226.1 - 0.53 8.9 11.8 0.59 8.8 11.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BTB PF00651.31 KFR05227.1 - 5e-20 71.8 0.0 8.6e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFR05227.1 - 1.3e-05 25.4 11.7 0.00021 21.6 1.9 3.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR05227.1 - 9.2e-05 23.0 15.6 0.029 15.2 2.2 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KFR05227.1 - 0.0048 17.6 4.6 0.18 12.5 0.3 3.4 1 1 2 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-C2H2 PF00096.26 KFR05227.1 - 0.019 15.4 16.8 0.44 11.1 1.5 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type HNH PF01844.23 KFR05227.1 - 0.023 14.9 3.4 4.2 7.6 0.1 2.8 2 0 0 2 2 2 0 HNH endonuclease zf-C2H2_6 PF13912.6 KFR05227.1 - 0.028 14.4 12.0 2.7 8.1 0.6 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFR05227.1 - 0.17 11.7 8.8 0.48 10.2 3.0 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type Zn_Tnp_IS1595 PF12760.7 KFR05227.1 - 0.36 10.8 4.3 0.91 9.5 4.3 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain FAM70 PF14967.6 KFR05228.1 - 8.3e-156 518.5 5.3 9.3e-156 518.4 5.3 1.0 1 0 0 1 1 1 1 FAM70 protein DUF4064 PF13273.6 KFR05228.1 - 0.00019 21.7 10.7 0.03 14.6 8.7 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF4064) Phage_holin_3_2 PF04550.12 KFR05228.1 - 0.054 14.0 1.0 0.054 14.0 1.0 2.0 2 0 0 2 2 2 0 Phage holin family 2 DUF2407_C PF13373.6 KFR05228.1 - 1.5 9.0 2.4 3.1 8.0 0.6 2.1 2 0 0 2 2 2 0 DUF2407 C-terminal domain Na_K-ATPase PF00287.18 KFR05229.1 - 3.3e-97 325.1 1.8 8e-97 323.8 1.8 1.5 1 1 0 1 1 1 1 Sodium / potassium ATPase beta chain Lamp PF01299.17 KFR05230.1 - 1.8e-52 177.1 12.9 3.3e-46 156.8 2.1 2.4 2 1 0 2 2 2 2 Lysosome-associated membrane glycoprotein (Lamp) ATP-synt_S1 PF05827.12 KFR05230.1 - 3.5e-06 26.9 1.1 3.5e-06 26.9 1.1 1.8 2 0 0 2 2 2 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Adeno_E3_CR2 PF02439.15 KFR05230.1 - 0.042 13.6 0.3 0.078 12.7 0.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Cullin PF00888.22 KFR05232.1 - 2.7e-212 706.7 18.4 4.3e-212 706.1 18.4 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KFR05232.1 - 1.3e-25 89.2 1.6 5.5e-25 87.2 1.6 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain SecA_SW PF07516.13 KFR05232.1 - 2.6e-05 24.4 0.2 2.6e-05 24.4 0.2 3.2 3 1 0 3 3 3 1 SecA Wing and Scaffold domain PG_binding_4 PF12229.8 KFR05232.1 - 0.35 11.2 2.5 2 8.7 0.1 3.2 3 0 0 3 3 3 0 Putative peptidoglycan binding domain Pre-PUA PF17832.1 KFR05233.1 - 1.2e-25 90.0 0.1 1.8e-25 89.4 0.1 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KFR05233.1 - 3.6e-21 74.9 0.1 6.3e-21 74.1 0.1 1.4 1 0 0 1 1 1 1 PUA domain Methyltr_RsmF_N PF17125.5 KFR05233.1 - 0.055 14.0 0.0 0.083 13.4 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF DUF1947 PF09183.10 KFR05233.1 - 0.068 13.5 0.0 0.14 12.5 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1947) Clat_adaptor_s PF01217.20 KFR05248.1 - 9.6e-27 93.7 0.3 1.1e-26 93.5 0.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AP-5_subunit_s1 PF15001.6 KFR05248.1 - 0.04 13.9 0.2 0.33 10.9 0.0 1.9 1 1 1 2 2 2 0 AP-5 complex subunit sigma-1 Chromo_shadow PF01393.19 KFR05249.1 - 1e-30 105.5 0.3 9.9e-28 96.0 0.0 2.4 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 KFR05249.1 - 1.3e-21 76.2 0.6 3e-18 65.5 0.5 2.4 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 KFR05249.1 - 0.01 16.0 0.1 0.041 14.1 0.1 2.0 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 SEA PF01390.20 KFR05254.1 - 8.6e-12 45.1 0.2 2.6e-11 43.6 0.2 1.8 1 0 0 1 1 1 1 SEA domain EGF_2 PF07974.13 KFR05254.1 - 0.00032 21.0 5.5 0.00049 20.4 5.5 1.2 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.27 KFR05254.1 - 0.0045 17.3 3.7 0.01 16.1 3.7 1.6 1 0 0 1 1 1 1 EGF-like domain Laminin_EGF PF00053.24 KFR05254.1 - 0.0072 16.4 1.4 0.013 15.6 1.4 1.3 1 0 0 1 1 1 1 Laminin EGF domain cEGF PF12662.7 KFR05254.1 - 0.49 10.4 2.3 1.2 9.1 2.3 1.7 1 0 0 1 1 1 0 Complement Clr-like EGF-like hEGF PF12661.7 KFR05254.1 - 3.2 8.5 7.1 7 7.5 7.1 1.6 1 0 0 1 1 1 0 Human growth factor-like EGF AzlD PF05437.12 KFR05254.1 - 4.7 7.5 10.3 76 3.6 0.3 3.6 1 1 5 6 6 6 0 Branched-chain amino acid transport protein (AzlD) AAA PF00004.29 KFR05258.1 - 2.3e-84 280.4 0.0 3.8e-43 147.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFR05258.1 - 2.1e-15 56.8 0.1 9.3e-08 32.0 0.0 3.5 4 0 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KFR05258.1 - 1e-11 45.0 0.0 0.00021 21.3 0.0 3.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 KFR05258.1 - 2.5e-10 40.0 0.1 7.6e-10 38.4 0.1 1.9 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 KFR05258.1 - 6.4e-10 38.8 0.3 0.00013 21.4 0.0 2.7 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_16 PF13191.6 KFR05258.1 - 6.6e-10 39.6 0.8 0.00016 22.1 0.2 4.1 2 2 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.14 KFR05258.1 - 5e-09 36.5 0.0 0.00081 19.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFR05258.1 - 1.9e-07 31.4 0.4 0.014 15.7 0.1 4.3 2 2 1 3 3 3 1 AAA domain Mg_chelatase PF01078.21 KFR05258.1 - 2.7e-07 30.2 0.7 0.0072 15.7 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KFR05258.1 - 3.4e-07 30.1 0.0 0.0077 16.0 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.6 KFR05258.1 - 4.4e-07 30.2 0.0 0.005 17.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KFR05258.1 - 1.1e-06 29.0 0.0 0.0069 16.8 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.6 KFR05258.1 - 3.5e-06 26.7 0.2 0.51 9.9 0.0 3.9 3 1 0 3 3 3 2 AAA domain Parvo_NS1 PF01057.17 KFR05258.1 - 5.7e-06 25.6 0.1 0.0042 16.2 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.6 KFR05258.1 - 5.7e-06 26.5 0.0 0.042 14.0 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Rad17 PF03215.15 KFR05258.1 - 6.7e-06 26.2 0.1 0.02 14.8 0.0 3.0 3 1 0 3 3 2 2 Rad17 P-loop domain AAA_28 PF13521.6 KFR05258.1 - 1.1e-05 25.7 0.0 0.027 14.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KFR05258.1 - 1.3e-05 24.7 0.0 0.11 12.0 0.0 3.0 4 0 0 4 4 3 2 P-loop containing dynein motor region AAA_14 PF13173.6 KFR05258.1 - 1.6e-05 24.9 0.0 0.097 12.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KFR05258.1 - 1.9e-05 25.2 0.0 0.014 16.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KFR05258.1 - 2e-05 24.6 0.0 0.075 13.0 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE CDC48_N PF02359.18 KFR05258.1 - 3.4e-05 23.9 0.0 7.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_3 PF07726.11 KFR05258.1 - 4.3e-05 23.4 0.0 0.33 10.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KFR05258.1 - 0.00017 21.1 0.0 0.089 12.1 0.0 2.5 2 0 0 2 2 2 1 KaiC Sigma54_activat PF00158.26 KFR05258.1 - 0.00049 19.8 0.0 0.27 10.9 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_24 PF13479.6 KFR05258.1 - 0.00086 19.1 0.0 0.055 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KFR05258.1 - 0.0012 19.4 0.0 1.5 9.3 0.0 3.0 2 1 0 3 3 3 1 ABC transporter NACHT PF05729.12 KFR05258.1 - 0.0016 18.4 0.3 0.3 11.0 0.0 2.9 3 0 0 3 3 2 1 NACHT domain DUF815 PF05673.13 KFR05258.1 - 0.0017 17.6 0.0 0.55 9.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_17 PF13207.6 KFR05258.1 - 0.0031 17.9 0.0 1.2 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KFR05258.1 - 0.004 16.5 0.1 0.88 8.8 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_11 PF13086.6 KFR05258.1 - 0.0044 16.8 0.0 0.9 9.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 KFR05258.1 - 0.0092 15.4 0.0 1.9 7.9 0.0 3.5 4 0 0 4 4 4 1 Bacterial TniB protein AAA_19 PF13245.6 KFR05258.1 - 0.024 14.9 0.0 0.57 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFR05258.1 - 0.027 14.2 0.0 0.28 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain IPT PF01745.16 KFR05258.1 - 0.035 13.5 0.1 0.86 8.9 0.1 2.2 2 0 0 2 2 2 0 Isopentenyl transferase NB-ARC PF00931.22 KFR05258.1 - 0.041 13.1 0.0 1.3 8.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain CDC48_2 PF02933.17 KFR05258.1 - 0.046 13.5 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 1 0 Cell division protein 48 (CDC48), domain 2 AAA_6 PF12774.7 KFR05258.1 - 0.049 12.6 0.6 0.16 10.9 0.0 2.1 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region PhoH PF02562.16 KFR05258.1 - 0.058 12.8 0.1 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Bac_DnaA PF00308.18 KFR05258.1 - 0.067 13.0 0.0 0.71 9.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial dnaA protein SKI PF01202.22 KFR05258.1 - 0.09 12.9 0.0 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase ATPase_2 PF01637.18 KFR05258.1 - 0.11 12.4 0.0 5.5 6.8 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Cytidylate_kin PF02224.18 KFR05258.1 - 0.12 12.1 0.2 4.2 7.0 0.0 2.6 3 0 0 3 3 2 0 Cytidylate kinase Cytidylate_kin2 PF13189.6 KFR05258.1 - 0.18 11.9 0.0 3.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family DUF2075 PF09848.9 KFR05258.1 - 0.27 10.4 0.0 0.72 9.0 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NUDIX PF00293.28 KFR05259.1 - 2.5e-18 66.4 0.0 3.8e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Nudix_hydro PF18290.1 KFR05259.1 - 6.6e-15 54.9 0.1 1.4e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 Nudix hydrolase domain FGF PF00167.18 KFR05260.1 - 1.3e-29 102.8 0.0 1.5e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor IL1 PF00340.19 KFR05260.1 - 0.00019 21.1 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 Interleukin-1 / 18 Glyco_transf_15 PF01793.16 KFR05260.1 - 0.068 12.4 0.1 0.069 12.4 0.1 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Cpn60_TCP1 PF00118.24 KFR05261.1 - 8.1e-16 57.7 0.8 8.6e-07 27.9 0.1 2.6 2 1 0 2 2 2 2 TCP-1/cpn60 chaperonin family EF-hand_1 PF00036.32 KFR05262.1 - 2e-34 114.5 17.9 5.4e-09 35.0 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFR05262.1 - 7.7e-31 106.4 9.3 1.8e-15 57.1 0.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFR05262.1 - 2.3e-27 92.5 11.2 3.3e-09 35.9 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KFR05262.1 - 3e-24 84.6 14.8 6.1e-12 45.2 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KFR05262.1 - 5.1e-16 57.4 18.9 1.1e-05 24.7 0.3 4.6 4 1 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KFR05262.1 - 1.3e-15 57.5 0.2 8.6e-07 29.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KFR05262.1 - 5.7e-06 26.2 8.0 0.26 11.2 0.1 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 KFR05262.1 - 0.00027 21.2 1.4 0.63 10.4 0.2 2.4 1 1 1 2 2 2 2 EF-hand domain DUF853 PF05872.12 KFR05262.1 - 0.00068 18.4 0.3 0.65 8.5 0.0 2.1 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF853) SurA_N_3 PF13624.6 KFR05262.1 - 0.00078 19.3 3.0 0.2 11.5 0.3 2.1 1 1 1 2 2 2 2 SurA N-terminal domain SPARC_Ca_bdg PF10591.9 KFR05262.1 - 0.0016 18.7 0.8 0.28 11.5 0.3 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KFR05262.1 - 0.0029 17.8 0.2 0.34 11.1 0.1 2.7 1 1 1 2 2 2 1 Dockerin type I domain DUF3349 PF11829.8 KFR05262.1 - 0.013 16.3 2.3 3.8 8.4 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) Sigma54_CBD PF04963.13 KFR05262.1 - 0.016 15.1 0.4 0.022 14.6 0.4 1.2 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain TerB PF05099.13 KFR05262.1 - 0.023 14.7 2.9 0.36 10.8 0.1 2.7 1 1 2 3 3 3 0 Tellurite resistance protein TerB SUB1_ProdP9 PF18213.1 KFR05262.1 - 0.024 14.5 1.3 0.036 13.9 0.3 1.8 1 1 1 2 2 2 0 SUB1 protease Prodomain ProdP9 SurA_N_2 PF13623.6 KFR05262.1 - 0.05 13.5 3.4 0.7 9.7 0.5 2.6 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_11 PF08976.11 KFR05262.1 - 0.055 14.4 0.1 8.5 7.3 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain PB1 PF00564.24 KFR05262.1 - 0.066 13.2 0.5 4.6 7.3 0.2 2.5 2 0 0 2 2 2 0 PB1 domain PMBR PF09373.10 KFR05262.1 - 0.078 13.2 0.5 70 3.8 0.0 4.2 5 0 0 5 5 5 0 Pseudomurein-binding repeat DUF4601 PF15373.6 KFR05262.1 - 0.085 11.8 0.1 0.19 10.6 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4601) Caleosin PF05042.13 KFR05262.1 - 0.1 12.5 1.7 10 6.0 0.0 3.3 1 1 3 4 4 4 0 Caleosin related protein LETM1 PF07766.13 KFR05262.1 - 0.11 11.8 2.4 0.24 10.7 1.1 2.2 1 1 0 1 1 1 0 LETM1-like protein SRI PF08236.11 KFR05262.1 - 0.37 11.0 4.3 1.3 9.2 0.0 3.1 2 1 1 3 3 3 0 SRI (Set2 Rpb1 interacting) domain DUF1542 PF07564.11 KFR05262.1 - 0.56 10.4 3.7 21 5.3 0.1 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) Gp-FAR-1 PF05823.12 KFR05262.1 - 1.2 9.5 6.4 1.5 9.2 0.2 2.9 2 1 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) IL15 PF02372.15 KFR05263.1 - 3.3e-12 46.6 1.3 4.1e-12 46.3 1.3 1.1 1 0 0 1 1 1 1 Interleukin 15 IL15 PF02372.15 KFR05264.1 - 9.1e-37 126.1 2.0 1e-36 125.9 2.0 1.1 1 0 0 1 1 1 1 Interleukin 15 A_deamin PF02137.18 KFR05265.1 - 2.6e-87 293.3 0.2 4.4e-87 292.6 0.2 1.3 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.26 KFR05265.1 - 1e-11 45.3 0.2 1.4e-10 41.7 0.0 2.4 2 0 0 2 2 2 1 Double-stranded RNA binding motif FSA_C PF10479.9 KFR05266.1 - 1.8e-161 538.8 8.8 4.8e-127 425.0 2.9 2.8 1 1 1 2 2 2 2 Fragile site-associated protein C-terminus Ion_trans PF00520.31 KFR05267.1 - 2.7e-32 112.0 17.3 4.1e-32 111.3 17.1 1.4 1 1 0 1 1 1 1 Ion transport protein TRP_2 PF08344.11 KFR05267.1 - 7.3e-28 96.6 1.1 1.5e-27 95.6 1.1 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II PKD_channel PF08016.12 KFR05267.1 - 3.5e-12 45.7 16.0 2.5e-09 36.3 9.1 2.2 2 0 0 2 2 2 2 Polycystin cation channel Ank_2 PF12796.7 KFR05267.1 - 2.9e-11 43.8 0.1 5.3e-08 33.3 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFR05267.1 - 1.8e-07 31.6 0.1 0.0024 18.4 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFR05267.1 - 9.5e-07 29.0 0.6 1 9.8 0.0 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFR05267.1 - 1.3e-06 28.3 3.5 1.8 9.4 0.0 5.1 5 0 0 5 5 4 2 Ankyrin repeat Ank PF00023.30 KFR05267.1 - 0.00028 21.2 0.4 2.5 8.7 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat MCM_N PF14551.6 KFR05267.1 - 0.071 13.7 0.1 0.25 12.0 0.1 1.9 1 0 0 1 1 1 0 MCM N-terminal domain DUF4252 PF14060.6 KFR05267.1 - 0.24 11.3 3.2 16 5.4 1.5 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4252) ING PF12998.7 KFR05267.1 - 0.26 11.9 6.3 8.3 7.1 2.9 2.6 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding BBS2_C PF14782.6 KFR05268.1 - 3.7e-05 22.7 0.8 9.2e-05 21.4 0.8 1.6 1 1 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 KFR05268.1 - 0.0018 18.3 0.0 0.0091 16.0 0.0 2.2 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region FlxA PF14282.6 KFR05268.1 - 0.006 16.5 0.5 0.013 15.5 0.5 1.4 1 0 0 1 1 1 1 FlxA-like protein AKNA PF12443.8 KFR05268.1 - 0.033 14.8 0.5 0.084 13.5 0.5 1.6 1 0 0 1 1 1 0 AT-hook-containing transcription factor ZapB PF06005.12 KFR05268.1 - 0.053 14.0 5.1 0.31 11.5 0.9 2.5 2 0 0 2 2 2 0 Cell division protein ZapB Jnk-SapK_ap_N PF09744.9 KFR05268.1 - 1.3 9.3 7.5 6.9 6.9 2.3 2.9 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 Cyclin_N PF00134.23 KFR05269.1 - 1.2e-49 167.2 0.3 2.3e-49 166.3 0.3 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFR05269.1 - 2.5e-30 105.0 0.5 1.4e-29 102.5 0.1 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain RNase_PH PF01138.21 KFR05270.1 - 1.8e-16 60.8 0.0 3.9e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFR05270.1 - 1.8e-11 43.9 0.0 5.1e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Annexin PF00191.20 KFR05271.1 - 3.1e-97 318.7 9.2 3.7e-25 87.8 0.2 4.0 4 0 0 4 4 4 4 Annexin DUF5069 PF16798.5 KFR05271.1 - 0.029 14.6 0.0 10 6.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5069) 7tm_1 PF00001.21 KFR05272.1 - 1.1e-58 198.7 21.6 1.4e-58 198.4 21.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFR05272.1 - 3.5e-07 30.1 16.2 3.5e-07 30.1 16.2 2.4 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFR05272.1 - 7e-06 25.6 24.3 9.8e-06 25.1 24.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFR05272.1 - 0.00017 21.5 21.9 0.0013 18.5 21.9 2.1 1 1 0 1 1 1 1 Olfactory receptor Herpes_US9 PF06072.11 KFR05272.1 - 0.02 14.7 0.2 0.02 14.7 0.2 3.5 4 0 0 4 4 4 0 Alphaherpesvirus tegument protein US9 Gaa1 PF04114.14 KFR05272.1 - 2.5 7.0 18.5 0.037 13.0 4.4 2.1 2 0 0 2 2 2 0 Gaa1-like, GPI transamidase component CC2-LZ PF16516.5 KFR05273.1 - 7.2e-11 42.3 32.2 1e-08 35.5 28.2 3.5 1 1 1 2 2 2 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator KxDL PF10241.9 KFR05273.1 - 0.00019 21.7 4.5 0.00019 21.7 4.5 3.7 3 1 0 3 3 3 1 Uncharacterized conserved protein FlxA PF14282.6 KFR05273.1 - 0.014 15.4 4.5 0.014 15.4 4.5 3.1 2 1 1 3 3 3 0 FlxA-like protein DUF4061 PF13270.6 KFR05273.1 - 0.024 15.0 2.8 0.024 15.0 2.8 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4061) NPV_P10 PF05531.12 KFR05273.1 - 0.039 14.4 3.5 1.2 9.7 0.2 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4047 PF13256.6 KFR05273.1 - 0.08 13.1 0.5 0.08 13.1 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4047) NusB PF01029.18 KFR05273.1 - 0.22 11.7 0.1 0.22 11.7 0.1 2.7 2 1 0 2 2 2 0 NusB family TPR_MLP1_2 PF07926.12 KFR05273.1 - 0.96 9.5 37.9 0.34 11.0 6.8 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 KFR05273.1 - 1.1 8.6 19.0 12 5.1 19.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2353 PF09789.9 KFR05273.1 - 1.1 8.6 30.9 1.8 7.8 30.9 1.4 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Leu_zip PF15294.6 KFR05273.1 - 1.1 8.7 30.6 0.41 10.1 23.4 2.1 1 1 1 2 2 2 0 Leucine zipper Fez1 PF06818.15 KFR05273.1 - 2.1 8.8 32.6 0.55 10.6 27.8 2.1 1 1 0 1 1 1 0 Fez1 GAS PF13851.6 KFR05273.1 - 2.6 7.3 37.3 0.46 9.8 5.4 2.7 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding HAUS-augmin3 PF14932.6 KFR05273.1 - 6.8 6.2 34.3 0.058 13.0 6.4 3.1 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 3 DUF2369 PF10179.9 KFR05274.1 - 1.6e-36 124.6 1.9 7.9e-31 106.3 0.5 3.1 3 0 0 3 3 3 2 Uncharacterised conserved protein (DUF2369) fn3 PF00041.21 KFR05274.1 - 6e-09 36.1 1.0 0.0068 16.7 0.0 4.0 3 1 0 3 3 3 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFR05274.1 - 7.2e-06 26.5 0.8 0.21 12.2 0.0 2.9 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain zf-H2C2_2 PF13465.6 KFR05275.1 - 1.3e-71 234.1 117.1 2.3e-10 40.4 0.6 16.9 17 0 0 17 17 17 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFR05275.1 - 2.2e-71 232.5 110.0 1.6e-06 28.2 0.6 16.2 16 0 0 16 16 16 16 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR05275.1 - 6.3e-59 191.5 112.4 0.00018 22.1 0.2 16.2 16 0 0 16 16 16 16 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFR05275.1 - 7.1e-35 118.6 97.0 6.7e-05 23.1 0.8 16.2 16 0 0 16 16 16 10 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFR05275.1 - 2.9e-32 110.1 91.3 3.3e-05 24.1 2.4 15.7 16 0 0 16 16 16 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFR05275.1 - 4.1e-26 90.4 105.2 0.001 19.0 0.6 16.7 15 2 1 16 16 16 11 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFR05275.1 - 1.9e-19 69.1 61.0 0.0035 17.0 0.1 14.2 15 0 0 15 15 15 7 zinc-finger C2H2-type zf-Di19 PF05605.12 KFR05275.1 - 4.8e-11 42.8 79.9 0.0029 17.8 1.9 9.4 5 3 3 9 9 9 7 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 KFR05275.1 - 2.2e-05 24.7 66.4 0.00041 20.6 2.0 8.7 1 1 7 9 9 9 3 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 KFR05275.1 - 3.5e-05 23.5 5.3 0.0026 17.5 0.3 14.6 15 2 0 15 15 14 3 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KFR05275.1 - 0.0017 18.7 90.5 4.1 7.8 0.8 13.5 1 1 9 12 12 12 3 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 KFR05275.1 - 0.0035 16.9 69.0 0.2 11.3 0.2 14.8 16 0 0 16 16 16 2 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 KFR05275.1 - 0.0044 17.7 8.9 0.0044 17.7 8.9 8.1 1 1 5 6 6 6 1 Zinc finger C2H2-type, 3 repeats Trm112p PF03966.16 KFR05275.1 - 0.0069 16.9 15.1 0.093 13.3 0.1 5.6 3 2 1 4 4 3 1 Trm112p-like protein BolA PF01722.18 KFR05275.1 - 0.015 15.5 23.1 5.4 7.4 0.1 7.4 4 3 3 7 7 7 0 BolA-like protein zf_C2H2_10 PF18414.1 KFR05275.1 - 0.089 12.3 12.0 2.5 7.7 0.0 5.6 5 0 0 5 5 5 0 C2H2 type zinc-finger FerB PF08150.12 KFR05275.1 - 0.23 12.1 0.6 2.3 8.9 0.3 2.9 1 1 1 2 2 2 0 FerB (NUC096) domain TRAF6_Z2 PF18048.1 KFR05275.1 - 0.38 10.9 0.1 0.38 10.9 0.1 7.5 9 0 0 9 9 8 0 TNF receptor-associated factor 6 zinc finger 2 zinc_ribbon_15 PF17032.5 KFR05275.1 - 0.7 10.7 76.4 1.1 10.1 2.0 8.8 2 1 7 9 9 9 0 zinc-ribbon family zinc_ribbon_9 PF14369.6 KFR05275.1 - 0.86 9.9 46.0 3.4 8.0 0.1 11.2 12 1 0 12 12 12 0 zinc-ribbon Zn-ribbon_8 PF09723.10 KFR05275.1 - 3.6 7.8 82.1 0.19 11.8 1.5 11.6 8 3 5 13 13 13 0 Zinc ribbon domain HORMA PF02301.18 KFR05276.1 - 2.1e-20 73.2 0.1 3.2e-20 72.6 0.1 1.3 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 KFR05276.1 - 0.00011 22.2 0.3 0.0025 17.8 0.3 2.2 1 1 0 1 1 1 1 Autophagy-related protein 101 Ribosomal_L30_N PF08079.12 KFR05277.1 - 8.2e-22 77.2 7.0 8.2e-22 77.2 7.0 1.9 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KFR05277.1 - 2.2e-14 53.1 1.6 2.2e-14 53.1 1.6 2.1 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e PDEase_I PF00233.19 KFR05278.1 - 3.7e-76 256.0 1.8 3.7e-76 256.0 1.8 2.3 2 1 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 KFR05278.1 - 1.2e-32 113.3 0.0 3.6e-15 56.8 0.0 2.6 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 KFR05278.1 - 1.3e-07 32.0 0.0 0.0042 17.4 0.0 2.5 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 KFR05278.1 - 0.00016 22.0 0.1 5.4 7.4 0.0 4.4 4 2 0 4 4 4 2 GAF domain UTP15_C PF09384.10 KFR05278.1 - 0.012 15.3 0.3 0.77 9.4 0.1 2.8 2 0 0 2 2 2 0 UTP15 C terminal ATLF PF07737.11 KFR05278.1 - 0.017 14.4 2.6 0.025 13.9 1.4 1.9 2 0 0 2 2 2 0 Anthrax toxin lethal factor, N- and C-terminal domain zf_ZIC PF18366.1 KFR05278.1 - 0.31 11.2 2.5 40 4.4 0.2 3.6 3 1 1 4 4 4 0 Zic proteins zinc finger domain Lipocalin PF00061.23 KFR05279.1 - 2.6e-16 60.1 1.4 2.7e-16 60.1 1.4 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 KFR05279.1 - 2e-12 47.2 1.5 2.3e-12 47.0 1.5 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_4 PF13648.6 KFR05279.1 - 0.024 15.6 2.6 0.048 14.6 2.6 1.6 1 1 0 1 1 1 0 Lipocalin-like domain UCH PF00443.29 KFR05280.1 - 1.3e-19 70.7 0.3 1.3e-19 70.7 0.3 1.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFR05280.1 - 2.3e-08 34.0 5.5 4.7e-08 33.0 5.5 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Calsarcin PF05556.11 KFR05281.1 - 2e-78 263.5 0.1 5.8e-78 261.9 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) PDZ_6 PF17820.1 KFR05282.1 - 2.2e-07 30.6 0.0 4.6e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Calsarcin PF05556.11 KFR05282.1 - 3.7e-06 26.7 6.3 0.02 14.4 1.7 2.6 2 1 0 2 2 2 2 Calcineurin-binding protein (Calsarcin) PDZ PF00595.24 KFR05282.1 - 4.1e-05 23.9 0.0 8.4e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFR05282.1 - 0.0058 16.9 0.1 0.041 14.2 0.0 2.3 2 0 0 2 2 2 1 PDZ domain MT-A70 PF05063.14 KFR05283.1 - 2.8e-63 212.9 0.0 3.9e-63 212.4 0.0 1.2 1 0 0 1 1 1 1 MT-A70 SRCR PF00530.18 KFR05284.1 - 5.1e-121 395.9 31.6 3.3e-33 114.2 4.6 4.1 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFR05284.1 - 6.9e-23 81.0 18.7 5.1e-06 26.9 1.9 4.6 4 1 0 4 4 4 4 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFR05284.1 - 2.3e-10 41.0 0.2 0.91 10.1 0.0 4.6 4 0 0 4 4 4 4 Hepsin, SRCR domain HMG_CoA_synt_N PF01154.17 KFR05284.1 - 0.041 13.8 4.2 0.38 10.6 0.1 2.8 3 0 0 3 3 3 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal HSNSD PF12062.8 KFR05285.1 - 6e-248 823.5 0.1 8.1e-248 823.0 0.1 1.2 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.27 KFR05285.1 - 3.8e-43 147.9 0.0 6.3e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFR05285.1 - 9.4e-09 36.0 0.2 0.00043 20.7 0.0 2.4 1 1 1 2 2 2 2 Sulfotransferase family HSNSD PF12062.8 KFR05286.1 - 6.2e-243 806.9 0.0 8.3e-243 806.5 0.0 1.2 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.27 KFR05286.1 - 6e-42 144.0 0.0 9.5e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFR05286.1 - 6.1e-09 36.6 0.2 0.00011 22.7 0.0 2.4 1 1 1 2 2 2 2 Sulfotransferase family UDPGT PF00201.18 KFR05287.1 - 2.4e-121 406.0 0.0 2.9e-121 405.7 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KFR05287.1 - 1.8e-06 28.0 0.0 3.4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Imm39 PF15568.6 KFR05287.1 - 0.0032 17.6 0.1 0.0063 16.6 0.1 1.4 1 0 0 1 1 1 1 Immunity protein 39 DUF2838 PF10998.8 KFR05287.1 - 0.12 12.7 1.3 0.27 11.5 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2838) Glyco_trans_1_4 PF13692.6 KFR05287.1 - 0.14 12.6 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 Sulfatase PF00884.23 KFR05288.1 - 5.5e-45 154.1 0.1 7.9e-45 153.6 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KFR05288.1 - 5.6e-05 23.9 0.0 0.00013 22.6 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase RVT_1 PF00078.27 KFR05340.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) C2 PF00168.30 KFR05351.1 - 5.3e-77 254.7 0.0 7.6e-17 61.5 0.0 7.4 6 1 0 6 6 6 6 C2 domain FerB PF08150.12 KFR05351.1 - 1.7e-32 111.8 0.0 5.7e-32 110.2 0.0 2.0 1 0 0 1 1 1 1 FerB (NUC096) domain Ferlin_C PF16165.5 KFR05351.1 - 3.1e-26 92.2 1.9 5.3e-22 78.4 0.1 2.6 1 1 1 2 2 2 2 Ferlin C-terminus FerI PF08151.12 KFR05351.1 - 3e-20 72.0 0.1 7.3e-20 70.8 0.1 1.7 1 0 0 1 1 1 1 FerI (NUC094) domain FerA PF08165.11 KFR05351.1 - 1.7e-19 69.5 1.1 2.4e-19 69.1 0.2 1.8 2 0 0 2 2 2 1 FerA (NUC095) domain Pex24p PF06398.11 KFR05351.1 - 7.9e-06 25.1 5.7 7.9e-06 25.1 5.7 3.7 3 1 1 4 4 4 2 Integral peroxisomal membrane peroxin PTEN_C2 PF10409.9 KFR05351.1 - 0.0017 18.1 0.0 0.004 16.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein NACHT_N PF17100.5 KFR05351.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase Sec15 PF04091.12 KFR05356.1 - 2.9e-100 335.8 2.1 2.9e-100 335.8 2.1 1.5 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like AKAP7_NLS PF10469.9 KFR05356.1 - 0.052 13.4 2.9 0.056 13.3 0.8 2.1 2 0 0 2 2 2 0 AKAP7 2'5' RNA ligase-like domain L27_1 PF09058.10 KFR05356.1 - 0.085 12.8 2.9 0.15 12.1 0.3 2.8 3 0 0 3 3 3 0 L27_1 adh_short PF00106.25 KFR05358.1 - 4.3e-15 55.7 0.0 5.8e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFR05358.1 - 1e-09 38.3 0.0 1.1e-09 38.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Mtc PF03820.17 KFR05359.1 - 2.4e-103 345.4 0.7 2.7e-103 345.3 0.7 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier DUF1980 PF09323.10 KFR05359.1 - 0.041 13.8 0.1 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Homeodomain PF00046.29 KFR05360.1 - 1e-22 79.7 3.3 1.5e-22 79.1 3.3 1.3 1 0 0 1 1 1 1 Homeodomain Homeodomain PF00046.29 KFR05361.1 - 1.7e-22 79.0 4.7 2.2e-22 78.6 4.7 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFR05361.1 - 0.054 13.4 0.1 0.094 12.6 0.1 1.5 1 0 0 1 1 1 0 Homeobox KN domain SET PF00856.28 KFR05362.1 - 7.8e-14 52.4 0.0 3.9e-13 50.2 0.0 2.0 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 KFR05362.1 - 0.00031 20.8 12.2 0.00031 20.8 12.2 3.0 3 2 0 3 3 3 1 MYND finger zf-HIT PF04438.16 KFR05362.1 - 1.2 9.0 13.4 0.064 13.1 4.9 2.8 2 0 0 2 2 2 0 HIT zinc finger PA PF02225.22 KFR05363.1 - 2.5e-06 27.4 0.0 3.8e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 PA domain Cpn60_TCP1 PF00118.24 KFR05364.1 - 8.6e-23 80.7 0.0 9e-23 80.7 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family F-box-like PF12937.7 KFR05365.1 - 8.5e-09 35.2 0.5 8.5e-09 35.2 0.5 2.9 4 0 0 4 4 4 1 F-box-like F-box PF00646.33 KFR05365.1 - 9.9e-05 22.1 0.8 0.00069 19.4 0.1 2.4 2 0 0 2 2 2 1 F-box domain Borrelia_P83 PF05262.11 KFR05365.1 - 0.0013 17.3 7.7 0.0017 16.9 7.7 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein zf-C2H2 PF00096.26 KFR05365.1 - 0.0065 16.9 2.1 0.016 15.6 2.1 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type LUC7 PF03194.15 KFR05365.1 - 0.01 15.5 3.5 0.021 14.5 3.5 1.5 1 0 0 1 1 1 0 LUC7 N_terminus DUF572 PF04502.13 KFR05365.1 - 0.027 14.1 4.5 0.047 13.3 4.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Atg14 PF10186.9 KFR05365.1 - 0.062 12.4 16.4 0.11 11.5 16.4 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-C2H2_4 PF13894.6 KFR05365.1 - 0.096 13.6 1.6 0.31 12.0 1.6 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFR05365.1 - 0.14 12.2 1.3 0.44 10.6 1.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Exonuc_VII_L PF02601.15 KFR05365.1 - 0.35 10.4 11.9 0.64 9.5 11.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Peptidase_C50 PF03568.17 KFR05365.1 - 1.4 7.9 10.6 3.2 6.8 10.6 1.5 1 0 0 1 1 1 0 Peptidase family C50 hDGE_amylase PF14701.6 KFR05365.1 - 2.1 7.3 5.8 3.3 6.7 5.8 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain UPF0242 PF06785.11 KFR05365.1 - 2.9 8.0 20.5 5.8 7.0 20.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FUSC PF04632.12 KFR05365.1 - 6.1 5.2 7.6 6.8 5.1 6.0 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family zf-C2H2 PF00096.26 KFR05366.1 - 9.8e-13 47.8 16.9 0.00012 22.3 3.7 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFR05366.1 - 1e-12 47.9 8.8 2.3e-07 30.9 1.3 4.8 4 1 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR05366.1 - 8e-10 38.7 14.0 0.0027 18.4 2.0 4.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFR05366.1 - 0.0083 16.1 6.9 1.1 9.3 0.5 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFR05366.1 - 0.023 15.0 9.7 0.18 12.1 6.0 2.8 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 KFR05366.1 - 0.071 13.0 11.1 2.9 7.9 0.7 3.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zf_RING PF16744.5 KFR05366.1 - 0.24 11.5 1.5 1.7 8.8 0.9 2.4 1 1 1 2 2 2 0 KIAA1045 RING finger zf-BED PF02892.15 KFR05366.1 - 0.36 10.9 6.7 1.4 9.0 6.4 2.2 1 1 0 1 1 1 0 BED zinc finger zf-RRN7 PF11781.8 KFR05366.1 - 0.39 10.4 2.9 0.79 9.5 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-C2H2_11 PF16622.5 KFR05366.1 - 1.1 9.0 8.4 17 5.3 0.3 3.6 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 KFR05366.1 - 3.5 8.2 8.5 5.6 7.5 0.5 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type NOP19 PF10863.8 KFR05367.1 - 0.0093 15.8 0.0 0.0093 15.8 0.0 1.2 1 0 0 1 1 1 1 Nucleolar protein 19 TetR_C_6 PF13977.6 KFR05369.1 - 0.21 11.8 1.3 0.41 10.9 0.3 1.9 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal Reprolysin PF01421.19 KFR05372.1 - 1.3e-70 237.3 0.0 1.3e-70 237.3 0.0 2.0 2 0 0 2 2 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.12 KFR05372.1 - 1.3e-32 112.6 10.9 1.3e-32 112.6 10.9 3.5 3 0 0 3 3 1 1 ADAM cysteine-rich Reprolysin_5 PF13688.6 KFR05372.1 - 8e-25 88.1 0.7 8e-25 88.1 0.7 2.0 2 0 0 2 2 1 1 Metallo-peptidase family M12 Pep_M12B_propep PF01562.19 KFR05372.1 - 1.4e-24 86.9 0.1 2.4e-24 86.1 0.1 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide Disintegrin PF00200.23 KFR05372.1 - 4.8e-20 72.1 29.6 4.8e-20 72.1 29.6 4.5 2 1 1 3 3 1 1 Disintegrin Reprolysin_3 PF13582.6 KFR05372.1 - 2.9e-17 63.3 0.0 6.2e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFR05372.1 - 6.4e-16 58.8 0.1 1.3e-15 57.8 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFR05372.1 - 2.1e-11 43.8 0.1 4.2e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.13 KFR05372.1 - 0.00075 19.8 12.2 0.00075 19.8 12.2 5.9 4 1 0 4 4 2 1 EGF-like domain Peptidase_M54 PF07998.11 KFR05372.1 - 0.035 14.1 0.3 0.11 12.5 0.3 1.8 1 0 0 1 1 1 0 Peptidase family M54 Tudor_2 PF18104.1 KFR05372.1 - 0.083 12.6 0.4 0.21 11.3 0.1 1.9 2 0 0 2 2 1 0 Jumonji domain-containing protein 2A Tudor domain Peptidase_M10 PF00413.24 KFR05372.1 - 0.099 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Matrixin UreE_N PF02814.15 KFR05372.1 - 0.18 11.4 0.0 0.42 10.3 0.0 1.6 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain Peptidase_M66 PF10462.9 KFR05372.1 - 3.7 6.4 5.8 0.21 10.5 0.5 1.5 2 0 0 2 2 2 0 Peptidase M66 Peptidase_M43 PF05572.13 KFR05372.1 - 3.9 7.4 12.3 2.3 8.1 0.0 3.1 4 0 0 4 4 2 0 Pregnancy-associated plasma protein-A bZIP_2 PF07716.15 KFR05376.1 - 0.0007 19.6 6.7 0.0014 18.7 6.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KFR05376.1 - 0.0064 16.6 1.1 0.011 15.9 1.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor DivIC PF04977.15 KFR05376.1 - 0.014 15.1 1.7 0.024 14.4 1.7 1.4 1 0 0 1 1 1 0 Septum formation initiator GAS PF13851.6 KFR05376.1 - 0.036 13.4 1.9 0.036 13.4 1.9 1.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding GIT_CC PF16559.5 KFR05376.1 - 0.094 12.6 0.7 0.15 11.9 0.2 1.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor IFP_35_N PF07334.13 KFR05376.1 - 0.17 12.0 0.2 0.31 11.1 0.2 1.3 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Phlebovirus_NSM PF07246.11 KFR05376.1 - 0.21 10.9 0.4 0.26 10.6 0.4 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M tRNA-synt_1g PF09334.11 KFR05377.1 - 2.4e-147 490.8 0.0 3e-147 490.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.20 KFR05377.1 - 3.5e-17 62.3 6.8 7.1e-17 61.3 6.8 1.5 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_1 PF00133.22 KFR05377.1 - 1.8e-07 29.8 0.3 0.00083 17.7 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) GST_C_2 PF13410.6 KFR05377.1 - 0.00014 21.8 0.9 0.00036 20.5 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFR05377.1 - 0.00022 21.4 0.0 0.00062 19.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Anticodon_1 PF08264.13 KFR05377.1 - 0.0015 18.5 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA GST_C_3 PF14497.6 KFR05377.1 - 0.008 16.4 0.0 0.025 14.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zinc-ribbons_6 PF07191.12 KFR05377.1 - 1.2 9.1 7.5 2.8 8.0 7.5 1.6 1 0 0 1 1 1 0 zinc-ribbons Tubulin PF00091.25 KFR05378.1 - 7.6e-18 65.4 0.0 8.6e-18 65.2 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain hNIFK_binding PF12196.8 KFR05379.1 - 0.054 13.0 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK PAP_central PF04928.17 KFR05379.1 - 0.091 11.7 0.1 0.1 11.6 0.1 1.0 1 0 0 1 1 1 0 Poly(A) polymerase central domain Dynamitin PF04912.14 KFR05380.1 - 1.3e-30 107.1 0.4 1.4e-30 107.0 0.4 1.0 1 0 0 1 1 1 1 Dynamitin GrpE PF01025.19 KFR05380.1 - 0.0074 16.0 0.1 0.01 15.5 0.1 1.1 1 0 0 1 1 1 1 GrpE ZapB PF06005.12 KFR05380.1 - 0.034 14.6 4.2 0.089 13.3 4.2 1.7 1 0 0 1 1 1 0 Cell division protein ZapB MbeD_MobD PF04899.12 KFR05380.1 - 0.04 14.0 2.3 0.072 13.2 2.3 1.4 1 0 0 1 1 1 0 MbeD/MobD like DUF3086 PF11285.8 KFR05380.1 - 0.042 12.9 0.1 0.042 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) GreA_GreB_N PF03449.15 KFR05380.1 - 0.058 13.6 1.3 0.1 12.8 1.3 1.4 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal AcylCoA_dehyd_C PF12186.8 KFR05380.1 - 0.15 12.2 1.1 0.23 11.6 0.3 1.6 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal FlaC_arch PF05377.11 KFR05380.1 - 0.4 11.1 2.1 1.1 9.7 0.8 2.0 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) bZIP_2 PF07716.15 KFR05380.1 - 2.8 8.1 5.5 2.1 8.5 3.3 1.9 1 1 1 2 2 2 0 Basic region leucine zipper Nramp PF01566.18 KFR05383.1 - 1.4e-118 396.0 13.4 1.4e-118 396.0 13.4 1.4 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein LETM1 PF07766.13 KFR05384.1 - 2.1e-67 227.3 0.4 2.4e-67 227.1 0.4 1.0 1 0 0 1 1 1 1 LETM1-like protein CP2 PF04516.15 KFR05385.1 - 9.8e-59 198.4 0.0 1.5e-58 197.8 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor SAM_3 PF18016.1 KFR05385.1 - 7.7e-19 67.3 0.0 3.5e-18 65.2 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DAZAP2 PF11029.8 KFR05386.1 - 3.6e-16 60.3 1.5 3.6e-16 60.3 1.5 1.4 2 0 0 2 2 2 1 DAZ associated protein 2 (DAZAP2) Trypsin PF00089.26 KFR05387.1 - 1.2e-66 224.7 5.1 1.4e-66 224.5 5.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFR05387.1 - 9.9e-08 33.0 0.1 1.4e-07 32.5 0.1 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Glycos_transf_2 PF00535.26 KFR05388.1 - 2e-24 86.3 0.0 3.9e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFR05388.1 - 7.2e-21 74.8 0.0 1.5e-20 73.7 0.0 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 KFR05388.1 - 2.1e-08 33.7 0.0 7.5e-08 31.9 0.1 1.8 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.6 KFR05388.1 - 0.00012 22.8 0.0 0.37 11.6 0.0 2.5 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Glyco_tranf_2_3 PF13641.6 KFR05388.1 - 0.00023 21.2 0.0 0.00086 19.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KFR05388.1 - 0.061 12.8 0.0 0.34 10.3 0.0 2.0 1 1 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KFR05388.1 - 0.078 12.9 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Glycosyl transferase family group 2 HCO3_cotransp PF00955.21 KFR05389.1 - 9.1e-245 813.2 9.1 1.2e-244 812.9 9.1 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 KFR05389.1 - 4.7e-103 344.7 0.1 4.7e-103 344.7 0.1 1.5 2 0 0 2 2 2 1 Band 3 cytoplasmic domain MIP PF00230.20 KFR05390.1 - 6.8e-81 271.3 9.3 7.9e-81 271.1 9.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein Bax1-I PF01027.20 KFR05391.1 - 2.4e-09 37.3 15.1 4e-09 36.6 15.1 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Phage_holin_3_6 PF07332.11 KFR05391.1 - 5.3 7.1 7.8 0.33 11.0 0.8 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Bin3 PF06859.12 KFR05392.1 - 1.9e-19 70.3 0.0 2.8e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 KFR05392.1 - 1.4e-05 25.0 0.0 2.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFR05392.1 - 1.9e-05 25.3 0.0 0.0015 19.2 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFR05392.1 - 0.0032 18.1 0.0 0.037 14.7 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFR05392.1 - 0.0044 17.7 0.1 0.036 14.8 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFR05392.1 - 0.18 11.6 0.0 0.32 10.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Filament PF00038.21 KFR05393.1 - 1.3e-75 254.9 31.1 1.4e-75 254.7 31.1 1.0 1 0 0 1 1 1 1 Intermediate filament protein V_ATPase_I PF01496.19 KFR05393.1 - 0.43 8.4 20.4 0.37 8.7 3.6 2.8 1 1 1 3 3 3 0 V-type ATPase 116kDa subunit family GAS PF13851.6 KFR05393.1 - 0.86 8.9 29.9 1.8 7.9 5.6 3.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 KFR05393.1 - 1.9 8.3 20.1 9.8 6.0 1.2 4.7 3 1 1 4 4 4 0 Septum formation initiator DUF4140 PF13600.6 KFR05393.1 - 4.5 7.8 11.0 30 5.1 0.0 4.3 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) TPR_MLP1_2 PF07926.12 KFR05393.1 - 6.6 6.8 28.2 0.29 11.2 3.1 4.6 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF883 PF05957.13 KFR05393.1 - 8.8 7.0 7.8 4.4 8.0 0.3 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Filament PF00038.21 KFR05395.1 - 1.1e-116 389.8 40.6 1.3e-116 389.6 40.6 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFR05395.1 - 2.8e-20 73.1 44.0 2.5e-17 63.5 2.2 3.2 2 1 1 3 3 3 2 Keratin type II head TPR_MLP1_2 PF07926.12 KFR05395.1 - 2.9e-06 27.4 40.7 0.0007 19.7 2.2 3.9 2 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KFR05395.1 - 0.00064 18.7 40.7 0.0034 16.3 8.9 3.7 1 1 2 3 3 3 2 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KFR05395.1 - 0.0014 18.7 33.8 0.03 14.4 11.2 3.7 1 1 3 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N PF09744.9 KFR05395.1 - 0.0032 17.7 31.0 0.046 13.9 3.5 3.4 2 1 1 3 3 3 2 JNK_SAPK-associated protein-1 CALCOCO1 PF07888.11 KFR05395.1 - 0.011 14.7 35.3 23 3.7 35.3 2.1 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ATG16 PF08614.11 KFR05395.1 - 0.014 15.6 7.4 0.014 15.6 7.4 3.2 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) FPP PF05911.11 KFR05395.1 - 0.023 12.9 29.4 0.39 8.8 15.2 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil ADIP PF11559.8 KFR05395.1 - 0.024 14.7 32.9 0.25 11.4 6.0 3.8 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding B2 PF11473.8 KFR05395.1 - 0.18 11.6 0.8 3.8 7.4 0.2 2.7 2 1 0 2 2 2 0 RNA binding protein B2 GAS PF13851.6 KFR05395.1 - 0.24 10.7 38.4 0.29 10.5 8.5 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF812 PF05667.11 KFR05395.1 - 0.3 9.9 34.1 0.75 8.6 17.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF812) Baculo_PEP_C PF04513.12 KFR05395.1 - 0.46 10.5 22.6 6 6.9 5.3 4.3 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF720 PF05302.11 KFR05395.1 - 0.49 10.2 11.3 0.23 11.3 2.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF720) DUF4407 PF14362.6 KFR05395.1 - 0.63 9.3 27.7 0.76 9.1 4.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Tropomyosin_1 PF12718.7 KFR05395.1 - 0.98 9.6 39.5 0.45 10.7 14.7 4.2 1 1 3 4 4 4 0 Tropomyosin like T2SSM PF04612.12 KFR05395.1 - 0.99 9.4 8.8 0.35 10.9 5.0 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M YvrJ PF12841.7 KFR05395.1 - 1.1 8.9 3.0 18 5.0 0.0 3.6 4 0 0 4 4 3 0 YvrJ protein family Taxilin PF09728.9 KFR05395.1 - 1.1 8.3 32.3 67 2.5 30.5 3.0 1 1 0 1 1 1 0 Myosin-like coiled-coil protein DUF1664 PF07889.12 KFR05395.1 - 1.4 9.0 20.3 4.5 7.3 1.7 4.4 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) Lebercilin PF15619.6 KFR05395.1 - 1.5 8.4 34.4 0.69 9.5 10.6 2.7 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease APG6_N PF17675.1 KFR05395.1 - 1.5 9.3 44.7 0.38 11.3 9.5 4.3 1 1 3 4 4 4 0 Apg6 coiled-coil region Fib_alpha PF08702.10 KFR05395.1 - 2 8.6 27.8 0.065 13.4 1.3 3.8 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family DUF1192 PF06698.11 KFR05395.1 - 2.4 8.3 16.2 0.16 12.1 3.0 3.8 3 1 1 4 4 3 0 Protein of unknown function (DUF1192) DUF3450 PF11932.8 KFR05395.1 - 3.3 7.0 33.3 0.3 10.4 5.4 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) DUF3584 PF12128.8 KFR05395.1 - 3.7 5.0 33.5 1.9 5.9 14.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Rootletin PF15035.6 KFR05395.1 - 4.3 7.3 27.3 4 7.4 7.7 2.4 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DASH_Duo1 PF08651.10 KFR05395.1 - 4.4 7.2 14.6 2.4 8.0 2.1 4.1 3 1 1 4 4 4 0 DASH complex subunit Duo1 Rab5-bind PF09311.11 KFR05395.1 - 6.6 6.0 35.7 0.13 11.7 11.1 3.2 1 1 1 2 2 1 0 Rabaptin-like protein ERM PF00769.19 KFR05395.1 - 6.9 6.4 37.9 15 5.3 9.2 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family PRKG1_interact PF15898.5 KFR05395.1 - 7.5 7.5 27.3 11 7.0 1.3 3.6 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain TraC PF07820.12 KFR05395.1 - 8.1 6.9 15.1 8 6.9 7.3 3.2 3 1 1 4 4 2 0 TraC-like protein DUF2203 PF09969.9 KFR05395.1 - 9.5 7.0 22.7 1.1 9.9 0.6 3.7 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) Filament PF00038.21 KFR05396.1 - 2.1e-112 375.8 27.4 2.4e-112 375.5 27.4 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFR05396.1 - 1.5e-14 54.5 47.6 2.9e-09 37.3 2.1 3.2 2 1 1 3 3 3 2 Keratin type II head BRE1 PF08647.11 KFR05396.1 - 0.012 15.6 2.7 0.012 15.6 2.7 4.4 3 2 1 4 4 4 0 BRE1 E3 ubiquitin ligase Taxilin PF09728.9 KFR05396.1 - 0.016 14.4 15.6 0.61 9.2 15.6 2.7 1 1 0 1 1 1 0 Myosin-like coiled-coil protein Baculo_PEP_C PF04513.12 KFR05396.1 - 0.017 15.2 11.0 0.11 12.6 0.8 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.9 KFR05396.1 - 0.018 15.1 20.8 0.031 14.3 3.2 4.0 1 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KFR05396.1 - 0.047 12.6 24.1 0.029 13.3 4.7 3.1 1 1 3 4 4 4 0 Spc7 kinetochore protein DUF5082 PF16888.5 KFR05396.1 - 0.055 13.8 0.6 0.055 13.8 0.6 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF5082) TPR_MLP1_2 PF07926.12 KFR05396.1 - 0.079 13.0 25.5 0.067 13.3 5.8 3.8 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein CHDCT2 PF08074.11 KFR05396.1 - 0.1 12.8 9.8 0.052 13.7 1.0 2.6 1 1 0 2 2 2 0 CHDCT2 (NUC038) domain DUF1451 PF07295.11 KFR05396.1 - 0.11 12.5 10.0 0.042 13.9 1.3 2.7 2 1 0 2 2 2 0 Zinc-ribbon containing domain SlyX PF04102.12 KFR05396.1 - 0.23 12.1 0.3 0.23 12.1 0.3 4.4 5 1 1 6 6 4 0 SlyX DUF1664 PF07889.12 KFR05396.1 - 0.25 11.4 11.4 4.3 7.4 0.3 3.9 3 2 0 3 3 3 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 KFR05396.1 - 0.29 11.3 21.1 0.049 13.8 5.7 3.5 2 1 0 3 3 3 0 Tropomyosin like Ax_dynein_light PF10211.9 KFR05396.1 - 0.31 11.0 20.7 0.21 11.5 1.4 4.2 1 1 1 4 4 4 0 Axonemal dynein light chain ADIP PF11559.8 KFR05396.1 - 0.39 10.8 20.2 0.079 13.0 3.8 4.0 2 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Lebercilin PF15619.6 KFR05396.1 - 0.65 9.6 20.1 0.15 11.7 5.5 3.4 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF4164 PF13747.6 KFR05396.1 - 0.7 10.2 10.6 5.4 7.4 0.5 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Jnk-SapK_ap_N PF09744.9 KFR05396.1 - 0.95 9.7 19.0 0.13 12.5 0.8 3.4 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Plk4_PB2 PF18409.1 KFR05396.1 - 1.9 9.2 4.8 11 6.8 0.6 3.0 2 1 1 3 3 3 0 Polo-like Kinase 4 Polo Box 2 UPF0242 PF06785.11 KFR05396.1 - 2.8 8.0 18.7 0.54 10.3 1.6 3.4 1 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus LPP PF04728.13 KFR05396.1 - 3 8.3 14.2 1.9 9.0 0.2 5.2 5 1 0 5 5 5 0 Lipoprotein leucine-zipper ACCA PF03255.14 KFR05396.1 - 3.6 7.4 12.9 9.4 6.1 0.3 3.6 1 1 2 4 4 4 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ApoLp-III PF07464.11 KFR05396.1 - 4.8 7.3 9.8 0.14 12.3 0.6 2.7 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 KFR05396.1 - 8.2 7.1 11.7 14 6.4 3.2 4.0 4 1 1 5 5 4 0 Bacterial protein of unknown function (DUF883) Filament PF00038.21 KFR05397.1 - 3.8e-114 381.5 36.7 4.4e-114 381.3 36.7 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFR05397.1 - 2.9e-30 105.5 30.4 2.9e-30 105.5 30.4 2.9 2 1 0 2 2 2 1 Keratin type II head CENP-F_leu_zip PF10473.9 KFR05397.1 - 0.00014 21.9 28.2 0.0044 17.0 8.0 3.5 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Taxilin PF09728.9 KFR05397.1 - 0.00028 20.2 24.3 0.0036 16.5 13.7 3.0 1 1 2 3 3 3 2 Myosin-like coiled-coil protein Spc7 PF08317.11 KFR05397.1 - 0.00045 19.2 5.3 0.00045 19.2 5.3 3.2 1 1 1 2 2 2 1 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KFR05397.1 - 0.00091 19.3 35.3 0.0019 18.3 11.4 3.9 1 1 2 4 4 4 2 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.7 KFR05397.1 - 0.002 18.3 11.4 0.002 18.3 11.4 3.8 2 1 2 4 4 4 1 Tropomyosin like TSNAXIP1_N PF15739.5 KFR05397.1 - 0.0041 17.5 1.3 0.0041 17.5 1.3 4.0 3 1 2 5 5 5 1 Translin-associated factor X-interacting N-terminus Phage_GP20 PF06810.11 KFR05397.1 - 0.0071 16.2 5.6 0.0071 16.2 5.6 3.5 2 1 1 3 3 3 1 Phage minor structural protein GP20 DHR10 PF18595.1 KFR05397.1 - 0.017 15.2 7.4 0.017 15.2 7.4 4.1 3 1 1 4 4 4 0 Designed helical repeat protein 10 domain Baculo_PEP_C PF04513.12 KFR05397.1 - 0.017 15.1 20.0 0.38 10.8 0.8 4.0 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.13 KFR05397.1 - 0.026 14.9 0.3 0.026 14.9 0.3 4.8 6 0 0 6 6 4 0 Lipoprotein leucine-zipper SlyX PF04102.12 KFR05397.1 - 0.03 14.9 0.4 0.03 14.9 0.4 4.5 3 1 1 4 4 4 0 SlyX ApoLp-III PF07464.11 KFR05397.1 - 0.032 14.3 1.0 0.032 14.3 1.0 4.0 2 2 2 4 4 4 0 Apolipophorin-III precursor (apoLp-III) DivIC PF04977.15 KFR05397.1 - 0.036 13.8 1.1 0.036 13.8 1.1 5.0 3 2 2 5 5 5 0 Septum formation initiator ADIP PF11559.8 KFR05397.1 - 0.045 13.8 28.8 0.065 13.3 10.4 4.0 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding AAA_13 PF13166.6 KFR05397.1 - 0.061 12.0 21.0 0.012 14.3 17.2 1.7 1 1 0 1 1 1 0 AAA domain Golgin_A5 PF09787.9 KFR05397.1 - 0.24 10.8 30.7 0.036 13.5 8.9 3.0 1 1 2 3 3 3 0 Golgin subfamily A member 5 TolA_bind_tri PF16331.5 KFR05397.1 - 0.26 11.4 19.4 4.1 7.5 0.1 5.4 4 1 1 5 5 5 0 TolA binding protein trimerisation APG6_N PF17675.1 KFR05397.1 - 0.46 11.0 37.6 0.065 13.8 5.7 4.2 1 1 3 4 4 4 0 Apg6 coiled-coil region DUF1451 PF07295.11 KFR05397.1 - 0.77 9.8 13.7 1.6 8.7 3.6 2.7 2 0 0 2 2 2 0 Zinc-ribbon containing domain DUF3450 PF11932.8 KFR05397.1 - 0.78 9.0 29.9 0.08 12.2 4.0 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF3450) DUF2746 PF10874.8 KFR05397.1 - 0.94 9.9 4.7 1.6 9.2 0.2 3.1 2 1 2 4 4 3 0 Protein of unknown function (DUF2746) BRE1 PF08647.11 KFR05397.1 - 1.4 9.0 30.2 0.026 14.6 4.1 4.4 2 1 1 4 4 4 0 BRE1 E3 ubiquitin ligase Alanine_zipper PF11839.8 KFR05397.1 - 1.7 9.1 11.2 0.68 10.3 7.8 2.1 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein FUSC PF04632.12 KFR05397.1 - 1.7 7.1 5.4 1.4 7.4 4.2 1.5 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF4988 PF16378.5 KFR05397.1 - 1.8 8.2 10.0 1.5 8.5 0.7 3.0 3 0 0 3 3 3 0 Domain of unknown function Atg14 PF10186.9 KFR05397.1 - 1.8 7.6 22.4 0.32 10.0 10.7 2.5 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 KFR05397.1 - 1.9 8.5 30.6 2.6 8.1 10.5 3.5 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Jnk-SapK_ap_N PF09744.9 KFR05397.1 - 3.8 7.7 30.7 0.51 10.6 3.9 3.8 1 1 1 3 3 3 0 JNK_SAPK-associated protein-1 TMF_TATA_bd PF12325.8 KFR05397.1 - 3.9 7.7 27.5 1.1 9.4 2.5 4.5 1 1 5 6 6 6 0 TATA element modulatory factor 1 TATA binding Plk4_PB2 PF18409.1 KFR05397.1 - 4.2 8.1 7.6 3.6 8.3 0.4 3.1 2 1 0 3 3 3 0 Polo-like Kinase 4 Polo Box 2 FlaC_arch PF05377.11 KFR05397.1 - 4.3 7.8 13.9 1.9 8.9 0.1 5.1 4 2 3 7 7 7 0 Flagella accessory protein C (FlaC) TSC22 PF01166.18 KFR05397.1 - 5 7.5 18.7 13 6.2 0.4 4.9 3 2 3 6 6 5 0 TSC-22/dip/bun family NPV_P10 PF05531.12 KFR05397.1 - 6.4 7.3 14.5 7.1 7.2 1.2 4.3 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 KFR05397.1 - 6.8 6.0 25.6 9.5e+02 -1.1 25.6 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 KFR05397.1 - 7 6.8 23.9 2.5 8.3 3.2 3.8 1 1 1 4 4 4 0 Fibrinogen alpha/beta chain family DUF4140 PF13600.6 KFR05397.1 - 7.4 7.1 23.7 1.5 9.3 2.9 5.0 2 1 2 5 5 5 0 N-terminal domain of unknown function (DUF4140) ACCA PF03255.14 KFR05397.1 - 7.5 6.4 17.7 3.3 7.6 1.2 4.3 2 1 3 5 5 5 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Filament PF00038.21 KFR05398.1 - 4.3e-115 384.6 36.1 5.1e-115 384.4 36.1 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFR05398.1 - 1.8e-43 148.5 52.6 1.8e-43 148.5 52.6 2.9 2 1 0 2 2 1 1 Keratin type II head TPR_MLP1_2 PF07926.12 KFR05398.1 - 1.7e-06 28.1 30.6 0.0012 18.9 11.1 3.7 2 1 1 3 3 3 2 TPR/MLP1/MLP2-like protein AAA_13 PF13166.6 KFR05398.1 - 9.8e-05 21.2 14.3 9.8e-05 21.2 14.3 1.8 1 1 1 2 2 2 1 AAA domain Spc7 PF08317.11 KFR05398.1 - 0.0019 17.2 33.0 0.058 12.3 15.0 3.2 1 1 3 4 4 4 4 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KFR05398.1 - 0.0035 17.4 28.2 0.083 12.9 8.6 3.7 1 1 3 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 KFR05398.1 - 0.0076 15.6 0.3 0.0076 15.6 0.3 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) ApoLp-III PF07464.11 KFR05398.1 - 0.0087 16.2 1.8 0.0087 16.2 1.8 3.2 2 1 0 3 3 3 1 Apolipophorin-III precursor (apoLp-III) MukF_M PF17192.4 KFR05398.1 - 0.01 15.5 14.2 0.097 12.4 6.7 2.4 2 0 0 2 2 2 0 MukF middle domain Baculo_PEP_C PF04513.12 KFR05398.1 - 0.013 15.5 1.1 0.013 15.5 1.1 4.4 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Jnk-SapK_ap_N PF09744.9 KFR05398.1 - 0.021 15.1 2.4 0.021 15.1 2.4 3.4 1 1 0 3 3 3 0 JNK_SAPK-associated protein-1 mRNA_decap_C PF16741.5 KFR05398.1 - 0.032 13.5 0.0 3.7 6.9 0.0 2.4 2 0 0 2 2 2 0 mRNA-decapping enzyme C-terminus ADIP PF11559.8 KFR05398.1 - 0.036 14.2 27.0 0.18 11.9 2.9 3.8 2 2 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 KFR05398.1 - 0.13 12.3 14.9 2.5 8.1 1.1 4.4 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) bZIP_1 PF00170.21 KFR05398.1 - 0.19 11.9 0.2 0.19 11.9 0.2 5.0 6 1 0 6 6 5 0 bZIP transcription factor DUF1451 PF07295.11 KFR05398.1 - 0.29 11.2 15.4 0.17 11.9 3.5 2.6 2 1 0 2 2 2 0 Zinc-ribbon containing domain DED PF01335.21 KFR05398.1 - 0.59 10.5 3.5 15 6.0 0.1 2.5 2 0 0 2 2 2 0 Death effector domain COMP PF11598.8 KFR05398.1 - 0.68 10.4 5.0 33 5.0 0.5 4.0 4 0 0 4 4 3 0 Cartilage oligomeric matrix protein ACCA PF03255.14 KFR05398.1 - 0.84 9.5 17.5 0.87 9.5 0.5 3.8 1 1 2 4 4 4 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Rx_N PF18052.1 KFR05398.1 - 1.1 9.6 11.0 1 9.7 2.7 3.0 3 0 0 3 3 3 0 Rx N-terminal domain TSC22 PF01166.18 KFR05398.1 - 2.2 8.6 14.5 5.2 7.5 0.2 4.5 3 2 1 4 4 4 0 TSC-22/dip/bun family ISG65-75 PF11727.8 KFR05398.1 - 4.4 6.5 10.4 0.32 10.2 4.3 1.9 2 0 0 2 2 2 0 Invariant surface glycoprotein Bap31_Bap29_C PF18035.1 KFR05398.1 - 5.7 7.0 8.8 1.6 8.8 0.2 3.7 3 1 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF5082 PF16888.5 KFR05398.1 - 5.9 7.2 24.4 0.42 10.9 4.9 3.9 1 1 3 4 4 4 0 Domain of unknown function (DUF5082) DUF883 PF05957.13 KFR05398.1 - 7.8 7.2 20.6 1.3 9.6 5.9 4.6 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF883) FlxA PF14282.6 KFR05398.1 - 8.9 6.4 20.1 1.3 9.1 4.7 3.9 2 1 1 3 3 3 0 FlxA-like protein Filament PF00038.21 KFR05399.1 - 3.3e-111 371.8 30.8 3.8e-111 371.6 30.8 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFR05399.1 - 7.9e-29 100.9 45.3 7.9e-29 100.9 45.3 3.0 2 1 0 2 2 2 1 Keratin type II head ATG16 PF08614.11 KFR05399.1 - 2e-05 25.0 24.3 0.00018 21.8 5.2 3.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KFR05399.1 - 0.0019 17.1 27.1 0.11 11.4 9.1 2.8 1 1 1 2 2 2 2 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KFR05399.1 - 0.0024 17.9 27.1 0.0041 17.2 3.1 3.7 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein COG5 PF10392.9 KFR05399.1 - 0.0098 16.1 2.1 0.0098 16.1 2.1 2.1 2 1 0 2 2 2 1 Golgi transport complex subunit 5 CENP-F_leu_zip PF10473.9 KFR05399.1 - 0.017 15.1 21.6 0.28 11.2 4.5 3.3 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRE1 PF08647.11 KFR05399.1 - 0.021 14.9 4.5 0.021 14.9 4.5 4.4 2 2 1 4 4 4 0 BRE1 E3 ubiquitin ligase Baculo_PEP_C PF04513.12 KFR05399.1 - 0.036 14.1 0.4 0.036 14.1 0.4 3.9 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus YlqD PF11068.8 KFR05399.1 - 0.066 13.6 0.3 0.066 13.6 0.3 3.9 1 1 2 4 4 4 0 YlqD protein PqqD PF05402.12 KFR05399.1 - 0.073 13.4 3.9 5.8 7.3 0.4 3.0 2 1 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) mRNA_decap_C PF16741.5 KFR05399.1 - 0.12 11.7 0.0 15 5.0 0.0 2.4 2 0 0 2 2 2 0 mRNA-decapping enzyme C-terminus Lebercilin PF15619.6 KFR05399.1 - 0.33 10.6 25.2 0.034 13.8 7.1 3.1 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Tropomyosin_1 PF12718.7 KFR05399.1 - 0.6 10.3 25.8 0.11 12.7 7.5 3.1 2 1 1 3 3 3 0 Tropomyosin like ADIP PF11559.8 KFR05399.1 - 0.69 10.0 23.9 4.5 7.3 5.8 4.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF5082 PF16888.5 KFR05399.1 - 1.2 9.5 18.3 1.8 8.9 1.9 3.7 1 1 1 3 3 3 0 Domain of unknown function (DUF5082) Tup_N PF08581.10 KFR05399.1 - 1.9 8.8 21.2 2.4 8.5 0.1 5.2 3 2 1 5 5 5 0 Tup N-terminal DUF3618 PF12277.8 KFR05399.1 - 2.5 8.4 4.5 4.4 7.6 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) Fib_alpha PF08702.10 KFR05399.1 - 2.6 8.2 18.8 0.43 10.8 0.8 3.7 1 1 3 5 5 5 0 Fibrinogen alpha/beta chain family Nbl1_Borealin_N PF10444.9 KFR05399.1 - 5.7 6.7 10.2 4.5 7.0 0.0 4.5 4 1 0 4 4 4 0 Nbl1 / Borealin N terminal FlxA PF14282.6 KFR05399.1 - 7.8 6.6 12.2 1.7 8.7 1.3 3.1 2 2 0 2 2 2 0 FlxA-like protein COMP PF11598.8 KFR05399.1 - 8.5 6.9 6.9 38 4.9 0.0 3.4 4 0 0 4 4 3 0 Cartilage oligomeric matrix protein TSC22 PF01166.18 KFR05399.1 - 8.5 6.8 14.6 16 5.9 0.3 5.0 3 1 2 5 5 5 0 TSC-22/dip/bun family Filament PF00038.21 KFR05400.1 - 6.6e-88 295.3 29.0 7.6e-88 295.1 29.0 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFR05400.1 - 8.5e-11 42.3 17.7 3.6e-08 33.7 17.7 2.1 1 1 0 1 1 1 1 Keratin type II head TPR_MLP1_2 PF07926.12 KFR05400.1 - 0.0087 16.1 16.8 0.037 14.1 0.3 3.6 3 1 0 3 3 3 2 TPR/MLP1/MLP2-like protein L1R_F9L PF02442.17 KFR05400.1 - 0.064 13.1 3.6 0.047 13.5 1.1 1.9 1 1 1 2 2 2 0 Lipid membrane protein of large eukaryotic DNA viruses Baculo_PEP_C PF04513.12 KFR05400.1 - 0.13 12.3 1.3 0.85 9.7 1.2 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_tran_CTD PF16326.5 KFR05400.1 - 0.13 12.5 5.5 0.19 12.0 1.0 3.3 1 1 2 3 3 3 0 ABC transporter C-terminal domain DUF2652 PF10851.8 KFR05400.1 - 1 9.5 6.8 0.17 12.0 0.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2652) DUF5344 PF17279.2 KFR05400.1 - 1.5 9.4 5.3 0.38 11.4 0.3 2.7 4 0 0 4 4 3 0 Family of unknown function (DUF5344) CHDCT2 PF08074.11 KFR05400.1 - 1.7 8.8 7.4 2.4 8.3 0.1 2.9 2 1 1 3 3 3 0 CHDCT2 (NUC038) domain DUF4407 PF14362.6 KFR05400.1 - 2.4 7.4 9.3 0.19 11.0 3.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 KFR05400.1 - 4.9 7.2 15.1 0.096 12.7 1.6 3.5 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 KFR05400.1 - 8.1 5.6 9.7 0.84 8.8 4.9 1.7 1 1 1 2 2 2 0 TMPIT-like protein Filament PF00038.21 KFR05401.1 - 1.9e-87 293.8 43.0 2.2e-87 293.6 43.0 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFR05401.1 - 5.7e-18 65.6 25.9 5.7e-18 65.6 25.9 2.8 2 1 0 2 2 1 1 Keratin type II head ATG16 PF08614.11 KFR05401.1 - 0.0047 17.2 33.3 0.015 15.5 13.8 2.9 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.7 KFR05401.1 - 0.018 15.2 9.6 0.018 15.2 9.6 3.1 2 1 1 3 3 2 0 Tropomyosin like DUF5320 PF17253.2 KFR05401.1 - 0.03 15.4 3.8 0.03 15.4 3.8 7.0 4 3 3 7 7 5 0 Family of unknown function (DUF5320) CENP-F_leu_zip PF10473.9 KFR05401.1 - 0.048 13.7 35.8 0.53 10.3 13.9 3.3 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 L1R_F9L PF02442.17 KFR05401.1 - 0.06 13.2 0.4 0.15 11.9 0.4 1.7 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses HsbA PF12296.8 KFR05401.1 - 0.16 12.4 3.3 7.6 7.0 0.1 2.8 2 2 0 2 2 2 0 Hydrophobic surface binding protein A KIP1 PF07765.12 KFR05401.1 - 0.46 10.6 12.5 0.078 13.1 2.5 3.8 3 1 1 4 4 4 0 KIP1-like protein TPR_MLP1_2 PF07926.12 KFR05401.1 - 0.47 10.5 34.4 0.11 12.6 5.0 3.7 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.19 KFR05401.1 - 0.9 7.4 24.9 0.0069 14.4 6.3 2.2 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family WXG100 PF06013.12 KFR05401.1 - 1.1 9.5 15.6 3.9 7.8 0.3 3.9 2 1 1 3 3 3 0 Proteins of 100 residues with WXG CHDCT2 PF08074.11 KFR05401.1 - 1.2 9.3 17.9 0.5 10.5 4.1 2.6 1 1 0 2 2 2 0 CHDCT2 (NUC038) domain HisKA_3 PF07730.13 KFR05401.1 - 3 8.4 8.5 27 5.4 0.8 4.1 2 1 0 3 3 3 0 Histidine kinase V-ATPase_G_2 PF16999.5 KFR05401.1 - 6 7.3 22.2 0.23 11.9 3.5 3.7 3 1 1 4 4 4 0 Vacuolar (H+)-ATPase G subunit Spc7 PF08317.11 KFR05401.1 - 8.2 5.2 38.3 7.8 5.3 15.2 2.8 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4407 PF14362.6 KFR05401.1 - 9.3 5.5 26.3 6.2 6.1 4.8 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Filament PF00038.21 KFR05402.1 - 3.2e-105 352.1 40.3 3.7e-105 351.9 40.3 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFR05402.1 - 2.2e-16 60.4 54.3 2.2e-16 60.4 54.3 3.7 2 1 1 3 3 3 1 Keratin type II head TPR_MLP1_2 PF07926.12 KFR05402.1 - 6.8e-05 22.9 40.1 0.0016 18.5 2.2 3.5 4 0 0 4 4 4 2 TPR/MLP1/MLP2-like protein AAA_13 PF13166.6 KFR05402.1 - 7.4e-05 21.6 16.4 7.4e-05 21.6 16.4 1.5 1 1 0 1 1 1 1 AAA domain Spc7 PF08317.11 KFR05402.1 - 0.0012 17.8 11.9 0.0012 17.8 11.9 2.8 1 1 2 3 3 3 3 Spc7 kinetochore protein ATG16 PF08614.11 KFR05402.1 - 0.0024 18.1 29.9 0.018 15.3 4.2 2.5 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) LPP PF04728.13 KFR05402.1 - 0.0037 17.6 4.8 0.038 14.4 1.0 3.9 4 0 0 4 4 4 1 Lipoprotein leucine-zipper Tropomyosin_1 PF12718.7 KFR05402.1 - 0.015 15.4 29.6 0.12 12.5 0.9 3.3 3 0 0 3 3 3 0 Tropomyosin like JIP_LZII PF16471.5 KFR05402.1 - 0.018 15.2 23.3 0.17 12.1 0.9 4.8 4 1 2 6 6 6 0 JNK-interacting protein leucine zipper II Baculo_PEP_C PF04513.12 KFR05402.1 - 0.019 15.0 12.1 4 7.5 0.4 4.1 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 KFR05402.1 - 0.021 15.0 3.0 0.021 15.0 3.0 3.3 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family HemY_N PF07219.13 KFR05402.1 - 0.19 11.9 2.1 0.36 11.1 2.1 1.3 1 0 0 1 1 1 0 HemY protein N-terminus ADIP PF11559.8 KFR05402.1 - 0.42 10.7 31.3 0.59 10.2 12.1 3.5 2 2 2 4 4 4 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 KFR05402.1 - 0.61 10.1 34.9 0.21 11.6 13.1 3.8 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Topoisom_I_N PF02919.15 KFR05402.1 - 1.2 8.6 4.5 0.68 9.4 1.0 2.1 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment CHDCT2 PF08074.11 KFR05402.1 - 1.4 9.1 16.3 0.72 10.0 1.5 2.8 1 1 0 2 2 2 0 CHDCT2 (NUC038) domain BLOC1_2 PF10046.9 KFR05402.1 - 1.9 8.8 16.7 0.97 9.8 1.0 3.9 2 2 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2353 PF09789.9 KFR05402.1 - 1.9 7.8 35.1 1 8.6 4.2 3.0 1 1 2 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) UPF0242 PF06785.11 KFR05402.1 - 3.2 7.8 35.4 1.6 8.8 6.0 3.5 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 KFR05402.1 - 3.5 7.7 22.7 0.23 11.5 3.2 4.1 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) BicD PF09730.9 KFR05402.1 - 6 5.2 30.5 0.14 10.6 14.5 2.2 1 1 0 2 2 2 0 Microtubule-associated protein Bicaudal-D DUF2721 PF11026.8 KFR05402.1 - 6.6 6.6 6.4 2.8 7.8 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) FlaC_arch PF05377.11 KFR05402.1 - 6.7 7.2 23.6 0.31 11.5 1.6 5.6 5 1 0 6 6 6 0 Flagella accessory protein C (FlaC) FapA PF03961.13 KFR05402.1 - 8.1 4.9 27.7 0.72 8.4 4.5 2.7 1 1 2 3 3 3 0 Flagellar Assembly Protein A DUF883 PF05957.13 KFR05402.1 - 9.8 6.9 17.6 4.6 7.9 6.4 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Filament PF00038.21 KFR05403.1 - 3.7e-106 355.2 42.1 4.3e-106 355.0 42.1 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFR05403.1 - 3.7e-18 66.2 162.8 4.4e-16 59.4 106.2 4.1 2 1 1 3 3 2 1 Keratin type II head TPR_MLP1_2 PF07926.12 KFR05403.1 - 0.00031 20.8 43.7 0.0024 17.9 3.0 3.7 3 1 0 3 3 3 2 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 KFR05403.1 - 0.00033 20.9 33.5 0.0054 17.0 6.7 2.7 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KFR05403.1 - 0.0007 18.6 40.9 0.0007 18.6 12.6 3.1 1 1 2 3 3 3 2 Spc7 kinetochore protein AAA_13 PF13166.6 KFR05403.1 - 0.0013 17.5 21.3 0.0013 17.5 21.3 1.9 1 1 0 1 1 1 1 AAA domain LPP PF04728.13 KFR05403.1 - 0.039 14.3 1.0 0.039 14.3 1.0 4.3 5 0 0 5 5 4 0 Lipoprotein leucine-zipper DAPDH_C PF16654.5 KFR05403.1 - 0.11 12.4 0.5 11 5.8 0.1 2.5 2 0 0 2 2 2 0 Diaminopimelic acid dehydrogenase C-terminal domain CENP-F_leu_zip PF10473.9 KFR05403.1 - 0.21 11.6 36.5 0.12 12.4 14.2 3.6 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 JIP_LZII PF16471.5 KFR05403.1 - 0.31 11.3 24.8 0.15 12.3 0.7 5.0 4 2 0 5 5 5 0 JNK-interacting protein leucine zipper II Baculo_PEP_C PF04513.12 KFR05403.1 - 0.38 10.8 20.9 6.7 6.8 0.6 4.2 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus FapA PF03961.13 KFR05403.1 - 0.94 8.0 29.8 0.6 8.7 6.7 2.5 1 1 2 3 3 3 0 Flagellar Assembly Protein A Topoisom_I_N PF02919.15 KFR05403.1 - 1.3 8.5 6.3 1.1 8.7 1.9 2.4 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF2353 PF09789.9 KFR05403.1 - 1.8 7.8 36.8 0.79 9.0 7.0 3.1 1 1 2 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) DUF883 PF05957.13 KFR05403.1 - 2.9 8.6 19.9 2.9 8.6 6.8 3.8 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) ADIP PF11559.8 KFR05403.1 - 5.2 7.1 37.6 0.41 10.7 12.8 3.8 2 2 1 3 3 3 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.10 KFR05403.1 - 7.3 6.8 33.0 0.076 13.2 5.2 3.6 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Asp2 PF16929.5 KFR05403.1 - 7.4 5.4 15.2 1.2 8.0 10.1 2.2 1 1 1 2 2 2 0 Accessory Sec system GspB-transporter Rx_N PF18052.1 KFR05403.1 - 7.9 6.8 13.1 20 5.5 4.3 3.5 2 2 0 3 3 3 0 Rx N-terminal domain L1R_F9L PF02442.17 KFR05403.1 - 8.9 6.1 9.0 0.73 9.6 0.6 2.9 2 1 2 4 4 4 0 Lipid membrane protein of large eukaryotic DNA viruses DUF4407 PF14362.6 KFR05403.1 - 9.6 5.5 26.8 0.74 9.1 2.6 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Filament PF00038.21 KFR05404.1 - 1.3e-113 379.8 29.4 1.5e-113 379.6 29.4 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFR05404.1 - 1.9e-36 125.6 99.5 9.5e-36 123.4 47.2 2.2 2 0 0 2 2 2 2 Keratin type II head TPR_MLP1_2 PF07926.12 KFR05404.1 - 1.4e-05 25.1 33.0 0.00071 19.6 10.8 3.7 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein BRE1 PF08647.11 KFR05404.1 - 0.0034 17.4 2.8 0.0034 17.4 2.8 4.5 3 2 1 4 4 4 1 BRE1 E3 ubiquitin ligase FPP PF05911.11 KFR05404.1 - 0.01 14.1 20.5 0.015 13.5 20.5 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil bZIP_1 PF00170.21 KFR05404.1 - 0.038 14.1 0.6 0.038 14.1 0.6 5.2 6 1 0 6 6 6 0 bZIP transcription factor SlyX PF04102.12 KFR05404.1 - 0.06 14.0 1.0 0.06 14.0 1.0 4.4 4 1 1 5 5 5 0 SlyX Golgin_A5 PF09787.9 KFR05404.1 - 0.073 12.5 28.3 0.1 12.0 7.9 3.3 2 1 0 3 3 3 0 Golgin subfamily A member 5 KxDL PF10241.9 KFR05404.1 - 0.076 13.3 0.6 0.076 13.3 0.6 4.5 2 1 2 4 4 4 0 Uncharacterized conserved protein DUF1664 PF07889.12 KFR05404.1 - 0.11 12.6 20.6 0.19 11.8 2.1 4.4 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) ADIP PF11559.8 KFR05404.1 - 0.13 12.4 31.2 0.39 10.8 8.4 4.1 3 1 0 4 4 4 0 Afadin- and alpha -actinin-Binding Bap31_Bap29_C PF18035.1 KFR05404.1 - 0.18 11.8 0.2 0.18 11.8 0.2 4.2 5 1 0 5 5 5 0 Bap31/Bap29 cytoplasmic coiled-coil domain Spc7 PF08317.11 KFR05404.1 - 0.32 9.8 38.1 0.12 11.2 15.5 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein NPV_P10 PF05531.12 KFR05404.1 - 0.4 11.2 13.5 0.97 9.9 0.9 4.3 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Ribosomal_S30AE PF02482.19 KFR05404.1 - 0.4 11.5 3.0 0.56 11.0 1.4 2.1 2 0 0 2 2 1 0 Sigma 54 modulation protein / S30EA ribosomal protein She9_MDM33 PF05546.11 KFR05404.1 - 0.46 10.3 10.3 0.75 9.6 0.3 2.8 2 1 0 2 2 2 0 She9 / Mdm33 family TraC PF07820.12 KFR05404.1 - 0.55 10.6 7.6 0.87 10.0 2.3 3.0 3 0 0 3 3 3 0 TraC-like protein KfrA_N PF11740.8 KFR05404.1 - 0.61 10.8 8.0 0.89 10.2 5.9 2.3 2 0 0 2 2 1 0 Plasmid replication region DNA-binding N-term COG5 PF10392.9 KFR05404.1 - 0.7 10.1 9.2 0.059 13.5 2.3 2.5 2 1 0 2 2 2 0 Golgi transport complex subunit 5 STAT_alpha PF01017.20 KFR05404.1 - 0.86 9.5 21.5 0.58 10.0 4.0 3.0 3 0 0 3 3 3 0 STAT protein, all-alpha domain LPP PF04728.13 KFR05404.1 - 0.94 9.9 8.3 4.8 7.7 0.2 4.2 4 0 0 4 4 4 0 Lipoprotein leucine-zipper CRR7 PF12095.8 KFR05404.1 - 1 9.9 9.4 0.38 11.2 0.4 3.7 2 2 2 4 4 3 0 Protein CHLORORESPIRATORY REDUCTION 7 Tropomyosin_1 PF12718.7 KFR05404.1 - 1.3 9.1 32.4 0.32 11.1 8.0 3.9 2 1 2 4 4 4 0 Tropomyosin like Baculo_PEP_C PF04513.12 KFR05404.1 - 1.5 8.9 17.2 0.15 12.1 0.7 4.2 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF812 PF05667.11 KFR05404.1 - 1.5 7.6 29.4 1.1 8.1 14.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF812) Rx_N PF18052.1 KFR05404.1 - 1.6 9.0 8.6 1 9.6 1.1 3.4 2 1 0 3 3 3 0 Rx N-terminal domain Jnk-SapK_ap_N PF09744.9 KFR05404.1 - 1.7 8.8 33.5 0.026 14.7 5.7 3.4 2 1 0 3 3 3 0 JNK_SAPK-associated protein-1 COMP PF11598.8 KFR05404.1 - 1.8 9.1 8.2 12 6.5 0.7 3.7 5 0 0 5 5 2 0 Cartilage oligomeric matrix protein ApoO PF09769.9 KFR05404.1 - 2.5 8.1 6.5 19 5.2 0.1 3.6 4 0 0 4 4 4 0 Apolipoprotein O COG2 PF06148.11 KFR05404.1 - 2.7 8.1 21.9 0.54 10.4 0.9 4.3 3 2 2 5 5 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.11 KFR05404.1 - 3.5 8.0 9.1 1.5 9.1 0.4 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Plk4_PB2 PF18409.1 KFR05404.1 - 4 8.2 6.5 5.9 7.6 1.2 3.2 2 1 1 3 3 3 0 Polo-like Kinase 4 Polo Box 2 CHDCT2 PF08074.11 KFR05404.1 - 5.4 7.2 13.7 1.7 8.8 0.1 3.5 2 1 1 3 3 3 0 CHDCT2 (NUC038) domain UPF0242 PF06785.11 KFR05404.1 - 6.7 6.8 30.4 1.6 8.8 6.0 3.9 1 1 3 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus Filament PF00038.21 KFR05405.1 - 2.8e-93 312.9 38.9 1.4e-59 202.2 24.0 2.0 1 1 1 2 2 2 2 Intermediate filament protein Keratin_2_head PF16208.5 KFR05405.1 - 1.3e-13 51.4 0.6 1.8e-13 50.9 0.6 1.2 1 0 0 1 1 1 1 Keratin type II head CENP-F_leu_zip PF10473.9 KFR05405.1 - 1.6e-06 28.2 37.5 4.2e-05 23.6 12.6 3.5 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CALCOCO1 PF07888.11 KFR05405.1 - 6.4e-06 25.3 35.8 3.9e-05 22.7 14.2 2.0 1 1 0 2 2 2 2 Calcium binding and coiled-coil domain (CALCOCO1) like TPR_MLP1_2 PF07926.12 KFR05405.1 - 6.8e-05 22.9 38.1 0.0018 18.3 1.4 4.0 2 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KFR05405.1 - 0.0019 17.1 37.7 0.021 13.7 19.0 3.8 1 1 2 3 3 3 2 Spc7 kinetochore protein APG6_N PF17675.1 KFR05405.1 - 0.0037 17.8 43.6 0.14 12.7 8.8 4.1 2 2 1 3 3 3 1 Apg6 coiled-coil region Ribosomal_S30AE PF02482.19 KFR05405.1 - 0.012 16.4 2.7 0.012 16.4 2.7 3.1 3 1 0 3 3 3 0 Sigma 54 modulation protein / S30EA ribosomal protein End3 PF12761.7 KFR05405.1 - 0.015 15.5 10.5 0.015 15.5 10.5 3.4 1 1 2 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 TSNAXIP1_N PF15739.5 KFR05405.1 - 0.018 15.4 3.8 0.018 15.4 3.8 4.4 1 1 3 5 5 4 0 Translin-associated factor X-interacting N-terminus VirD1 PF07328.11 KFR05405.1 - 0.019 15.0 0.6 0.1 12.5 0.0 2.4 2 1 1 3 3 3 0 T-DNA border endonuclease VirD1 DUF812 PF05667.11 KFR05405.1 - 0.035 13.0 29.4 0.0086 15.0 14.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF4407 PF14362.6 KFR05405.1 - 0.09 12.1 21.8 0.38 10.1 2.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ADIP PF11559.8 KFR05405.1 - 0.092 12.8 32.8 0.47 10.5 13.3 3.6 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.7 KFR05405.1 - 0.18 12.0 36.1 2.5 8.3 15.6 3.6 2 2 0 3 3 3 0 Tropomyosin like DUF1664 PF07889.12 KFR05405.1 - 0.19 11.8 17.5 2.3 8.2 1.3 4.2 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 KFR05405.1 - 0.2 11.9 32.9 0.18 12.0 7.0 3.3 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) TraC PF07820.12 KFR05405.1 - 0.21 12.0 16.4 0.098 13.0 7.4 3.3 3 1 0 3 3 3 0 TraC-like protein Baculo_PEP_C PF04513.12 KFR05405.1 - 0.22 11.6 15.8 0.49 10.4 1.6 3.8 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cep57_MT_bd PF06657.13 KFR05405.1 - 0.28 11.7 21.8 0.16 12.5 2.6 4.7 4 2 2 6 6 5 0 Centrosome microtubule-binding domain of Cep57 BRE1 PF08647.11 KFR05405.1 - 0.6 10.2 36.2 0.052 13.6 6.4 4.5 1 1 3 5 5 5 0 BRE1 E3 ubiquitin ligase Fez1 PF06818.15 KFR05405.1 - 0.6 10.5 30.6 0.89 10.0 21.6 2.4 1 1 1 2 2 2 0 Fez1 DUF4140 PF13600.6 KFR05405.1 - 0.85 10.1 26.5 3.9 8.0 5.9 5.2 2 2 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF1451 PF07295.11 KFR05405.1 - 1 9.4 20.7 0.71 9.9 2.5 2.7 3 0 0 3 3 2 0 Zinc-ribbon containing domain Mt_ATP-synt_D PF05873.12 KFR05405.1 - 1 9.2 18.7 5.8 6.8 3.2 3.3 2 2 1 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) Acetyltransf_6 PF13480.7 KFR05405.1 - 1.1 9.4 5.9 4.5 7.4 0.9 2.7 3 0 0 3 3 2 0 Acetyltransferase (GNAT) domain ERM PF00769.19 KFR05405.1 - 1.2 8.9 38.5 2.3 7.9 11.2 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Taxilin PF09728.9 KFR05405.1 - 1.9 7.6 35.4 2.1 7.4 14.8 2.5 1 1 1 2 2 2 0 Myosin-like coiled-coil protein Laminin_II PF06009.12 KFR05405.1 - 2.1 8.4 23.1 0.1 12.6 2.6 3.9 1 1 3 4 4 4 0 Laminin Domain II ApoO PF09769.9 KFR05405.1 - 2.9 7.9 9.3 22 5.0 0.0 4.3 2 2 2 4 4 4 0 Apolipoprotein O STAT_alpha PF01017.20 KFR05405.1 - 3.7 7.4 27.0 0.24 11.3 2.8 3.4 1 1 1 3 3 3 0 STAT protein, all-alpha domain FliD_N PF02465.18 KFR05405.1 - 3.8 8.3 18.5 3 8.6 0.2 4.3 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus GAS PF13851.6 KFR05405.1 - 4.1 6.7 40.9 0.39 10.1 19.5 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 KFR05405.1 - 5.2 6.9 34.3 12 5.6 21.1 2.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF4201 PF13870.6 KFR05405.1 - 5.2 6.8 32.0 0.45 10.2 4.5 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) Fib_alpha PF08702.10 KFR05405.1 - 6.1 7.0 23.4 1.7 8.8 6.7 3.5 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family TRAF_BIRC3_bd PF16673.5 KFR05405.1 - 6.6 6.6 15.3 5.3 6.9 2.2 4.1 3 3 1 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain Lectin_N PF03954.14 KFR05405.1 - 7.9 6.2 13.5 33 4.2 0.2 3.8 1 1 1 3 3 3 0 Hepatic lectin, N-terminal domain COMP PF11598.8 KFR05405.1 - 9.4 6.8 11.4 2.4 8.7 1.4 3.6 4 0 0 4 4 2 0 Cartilage oligomeric matrix protein RRM_1 PF00076.22 KFR05406.1 - 1.4e-12 47.3 0.0 2.1e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFR05406.1 - 0.0024 17.9 0.0 0.0044 17.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif HEAT_EZ PF13513.6 KFR05408.1 - 1.6e-33 114.6 1.2 1.5e-12 47.7 0.0 10.8 8 2 4 12 12 12 4 HEAT-like repeat HEAT PF02985.22 KFR05408.1 - 4.6e-29 98.0 10.2 0.0052 16.9 0.0 11.7 11 1 0 11 11 11 6 HEAT repeat HEAT_2 PF13646.6 KFR05408.1 - 1.1e-18 67.4 0.0 7.1e-06 26.3 0.0 6.5 5 2 2 7 7 7 4 HEAT repeats Cnd1 PF12717.7 KFR05408.1 - 4.3e-17 62.6 0.5 0.00048 20.2 0.2 4.6 3 1 1 4 4 4 4 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 KFR05408.1 - 1.3e-15 57.0 0.1 8.1e-15 54.5 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 KFR05408.1 - 5.5e-15 55.7 0.8 0.0013 19.3 0.2 6.9 5 2 3 8 8 8 5 Vacuolar 14 Fab1-binding region Arm PF00514.23 KFR05408.1 - 4e-13 48.9 2.2 0.017 15.2 0.0 7.9 8 0 0 8 8 7 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 KFR05408.1 - 3e-10 39.3 4.9 0.001 17.8 0.4 5.0 2 2 1 4 4 4 3 Adaptin N terminal region UNC45-central PF11701.8 KFR05408.1 - 3.9e-05 23.7 2.4 0.0089 16.0 0.1 3.9 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central Dopey_N PF04118.14 KFR05408.1 - 0.00027 20.1 0.5 0.0015 17.7 0.0 2.3 2 1 0 2 2 2 1 Dopey, N-terminal CLASP_N PF12348.8 KFR05408.1 - 0.00051 19.7 0.8 1.3 8.6 0.0 4.4 3 2 1 4 4 4 1 CLASP N terminal RTP1_C1 PF10363.9 KFR05408.1 - 0.0015 18.7 0.1 0.075 13.2 0.1 3.6 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF3437 PF11919.8 KFR05408.1 - 0.0074 16.2 0.4 3.6 7.6 0.0 4.7 5 0 0 5 5 5 1 Domain of unknown function (DUF3437) MMS19_C PF12460.8 KFR05408.1 - 0.0078 15.4 4.0 1 8.4 0.1 4.1 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal DUF3689 PF12463.8 KFR05408.1 - 0.023 14.0 0.0 0.13 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3689) TAFH PF07531.14 KFR05408.1 - 0.099 12.8 1.3 12 6.1 0.0 3.8 4 1 1 5 5 3 0 NHR1 homology to TAF DUF2457 PF10446.9 KFR05408.1 - 0.68 9.0 8.1 0.97 8.5 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 KFR05408.1 - 0.91 7.5 4.8 1.1 7.3 3.6 1.7 2 0 0 2 2 2 0 DNA polymerase phi NOA36 PF06524.12 KFR05408.1 - 1.9 7.7 4.2 3.3 7.0 4.2 1.3 1 0 0 1 1 1 0 NOA36 protein TFIIA PF03153.13 KFR05408.1 - 2.5 8.0 6.0 3.7 7.4 6.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MRP-S27 PF10037.9 KFR05409.1 - 4.4e-08 32.4 4.8 6.8e-08 31.8 4.3 1.5 1 1 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 PPR_2 PF13041.6 KFR05409.1 - 9.9e-08 32.1 0.0 3.2e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 PPR repeat family PPR PF01535.20 KFR05409.1 - 6.5e-05 22.9 0.1 0.00034 20.7 0.1 2.3 2 0 0 2 2 2 1 PPR repeat DED PF01335.21 KFR05409.1 - 0.0078 16.5 6.5 0.55 10.6 0.5 4.0 4 0 0 4 4 4 1 Death effector domain PPR_3 PF13812.6 KFR05409.1 - 0.012 15.7 3.1 0.056 13.5 0.0 2.7 3 0 0 3 3 3 0 Pentatricopeptide repeat domain PPR_1 PF12854.7 KFR05409.1 - 0.019 14.7 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 PPR repeat MRP-S27 PF10037.9 KFR05410.1 - 2.3e-110 369.2 12.5 5e-110 368.0 12.5 1.5 1 1 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 PPR_1 PF12854.7 KFR05410.1 - 0.00015 21.4 0.1 0.00054 19.6 0.1 1.9 2 0 0 2 2 2 1 PPR repeat PPR_2 PF13041.6 KFR05410.1 - 0.00046 20.3 0.0 0.0012 19.0 0.0 1.8 1 0 0 1 1 1 1 PPR repeat family PPR PF01535.20 KFR05410.1 - 0.0022 18.1 0.1 0.016 15.5 0.0 2.5 2 0 0 2 2 2 1 PPR repeat PPR_3 PF13812.6 KFR05410.1 - 0.017 15.2 0.1 0.048 13.7 0.1 1.8 1 0 0 1 1 1 0 Pentatricopeptide repeat domain SNF2_N PF00176.23 KFR05415.1 - 1.1e-73 248.0 1.7 2.2e-73 247.0 1.7 1.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain BRK PF07533.16 KFR05415.1 - 2e-18 65.7 0.1 4.1e-18 64.7 0.1 1.6 1 0 0 1 1 1 1 BRK domain ResIII PF04851.15 KFR05415.1 - 5.5e-10 39.5 0.0 1.5e-09 38.1 0.0 1.7 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KFR05415.1 - 4.2e-05 23.3 0.0 0.00012 21.9 0.0 1.8 1 1 0 1 1 1 1 SWI2/SNF2 ATPase DEAD PF00270.29 KFR05415.1 - 4.6e-05 23.2 0.0 8.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Kelch_1 PF01344.25 KFR05421.1 - 8e-91 297.4 21.7 1.5e-17 62.9 0.7 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFR05421.1 - 7.1e-52 172.1 9.0 2.4e-10 40.3 0.2 6.4 1 1 5 6 6 6 6 Kelch motif Kelch_2 PF07646.15 KFR05421.1 - 3.1e-41 137.8 8.7 3.9e-09 36.1 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 KFR05421.1 - 1.8e-28 98.3 3.4 2.2e-06 27.5 0.1 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KFR05421.1 - 1.9e-26 91.7 10.4 2.6e-06 27.6 0.3 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain BTB PF00651.31 KFR05421.1 - 3.9e-25 88.2 0.1 5.9e-25 87.7 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KFR05421.1 - 4.5e-11 42.8 0.2 1.4e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 KFR05421.1 - 1.1e-10 41.3 14.5 0.014 15.4 0.1 6.2 6 0 0 6 6 6 4 Kelch motif DUF3342 PF11822.8 KFR05421.1 - 0.00022 21.3 0.1 0.00048 20.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) PQQ_3 PF13570.6 KFR05421.1 - 0.005 17.3 6.8 2.9 8.5 0.0 4.7 5 0 0 5 5 4 2 PQQ-like domain Glu_cyclase_2 PF05096.12 KFR05421.1 - 0.0052 16.2 0.0 0.058 12.8 0.0 2.3 2 1 0 2 2 2 1 Glutamine cyclotransferase Peptidase_S9_N PF02897.15 KFR05421.1 - 0.2 10.4 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain FAST_1 PF06743.15 KFR05422.1 - 8.3e-06 25.7 0.1 1.1e-05 25.2 0.1 1.2 1 0 0 1 1 1 1 FAST kinase-like protein, subdomain 1 NAC PF01849.18 KFR05423.1 - 1.8e-23 82.2 0.3 4e-23 81.1 0.2 1.7 2 0 0 2 2 2 1 NAC domain Ribosomal_L30 PF00327.20 KFR05423.1 - 0.054 13.4 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e CCM2_C PF16545.5 KFR05424.1 - 4.9e-45 152.1 0.3 8.6e-45 151.4 0.3 1.4 1 0 0 1 1 1 1 Cerebral cavernous malformation protein, harmonin-homology PID PF00640.23 KFR05424.1 - 0.0057 16.7 0.0 0.023 14.7 0.0 2.0 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) DUF1722 PF08349.11 KFR05424.1 - 0.031 14.6 0.1 0.086 13.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Inv-AAD PF18785.1 KFR05424.1 - 0.15 12.0 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase HTH_48 PF17906.1 KFR05424.1 - 0.18 12.0 0.0 0.48 10.6 0.0 1.7 1 0 0 1 1 1 0 HTH domain in Mos1 transposase CotJA PF11007.8 KFR05425.1 - 0.0036 17.1 1.8 0.2 11.5 0.1 6.1 6 1 0 7 7 7 4 Spore coat associated protein JA (CotJA) Lactococcin PF04369.13 KFR05425.1 - 0.059 13.5 6.8 22 5.3 0.1 3.8 3 1 0 3 3 3 0 Lactococcin-like family CpcD PF01383.21 KFR05425.1 - 1.2 9.5 3.8 38 4.7 0.1 3.5 2 1 2 5 5 5 0 CpcD/allophycocyanin linker domain OCRE PF17780.1 KFR05425.1 - 3.8 7.6 9.1 85 3.3 0.2 4.2 4 0 0 4 4 4 0 OCRE domain Casein_kappa PF00997.18 KFR05426.1 - 0.00013 22.1 14.3 0.21 11.7 0.7 3.1 1 1 2 3 3 3 3 Kappa casein CotJA PF11007.8 KFR05426.1 - 0.00033 20.4 6.0 0.19 11.6 0.1 5.8 7 0 0 7 7 7 3 Spore coat associated protein JA (CotJA) Lactococcin PF04369.13 KFR05426.1 - 0.022 14.9 6.3 21 5.4 0.1 3.7 3 0 0 3 3 3 0 Lactococcin-like family CpcD PF01383.21 KFR05426.1 - 0.53 10.6 5.3 73 3.7 0.1 3.7 1 1 0 3 3 3 0 CpcD/allophycocyanin linker domain LpqV PF17301.2 KFR05426.1 - 4.5 7.5 11.8 22 5.4 1.1 3.0 1 1 2 3 3 3 0 Putative lipoprotein LpqV ELP6 PF09807.9 KFR05428.1 - 1.9e-103 345.3 2.3 2.1e-103 345.1 2.3 1.0 1 0 0 1 1 1 1 Elongation complex protein 6 SWIRM-assoc_2 PF16496.5 KFR05429.1 - 4.5e-152 506.7 17.0 4.5e-152 506.7 17.0 2.7 2 2 0 2 2 2 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 KFR05429.1 - 5.1e-31 106.9 2.0 6.7e-31 106.5 0.1 2.2 2 0 0 2 2 2 1 SWIRM domain SWIRM-assoc_3 PF16498.5 KFR05429.1 - 8.2e-31 106.1 1.3 8.2e-31 106.1 1.3 2.8 2 1 0 2 2 2 1 SWIRM-associated domain at the C-terminal SWIRM-assoc_1 PF16495.5 KFR05429.1 - 8.5e-29 99.4 16.6 8.5e-29 99.4 16.6 2.5 3 0 0 3 3 3 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KFR05429.1 - 1.3e-12 47.7 0.2 2.8e-12 46.6 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFR05429.1 - 1.3e-07 31.8 0.0 4.5e-07 30.0 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Chromo PF00385.24 KFR05429.1 - 0.052 13.5 0.2 0.15 12.0 0.2 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF2618 PF10940.8 KFR05429.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) DUF919 PF06034.11 KFR05429.1 - 0.52 10.2 9.3 0.18 11.7 5.3 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) HA2 PF04408.23 KFR05430.1 - 3e-14 53.2 0.0 8.7e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFR05430.1 - 2.2e-13 50.5 0.0 4.9e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.26 KFR05430.1 - 8.7e-11 42.4 1.9 2e-05 25.2 0.5 2.5 2 0 0 2 2 2 2 Double-stranded RNA binding motif OB_NTP_bind PF07717.16 KFR05430.1 - 6.2e-08 32.9 0.0 1.5e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KFR05430.1 - 2.7e-05 24.0 0.0 5.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Dicer_dimer PF03368.14 KFR05430.1 - 0.00011 22.3 0.2 0.031 14.4 0.1 3.3 3 0 0 3 3 3 1 Dicer dimerisation domain AAA_19 PF13245.6 KFR05430.1 - 0.011 16.1 0.0 0.036 14.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFR05430.1 - 0.012 15.9 0.0 0.039 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KFR05430.1 - 0.059 12.8 0.0 0.69 9.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.27 KFR05430.1 - 0.16 12.5 0.0 0.61 10.6 0.0 2.0 1 0 0 1 1 1 0 ABC transporter DUF5343 PF17278.2 KFR05430.1 - 0.18 11.9 0.0 28 4.8 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5343) Tubulin-binding PF00418.19 KFR05431.1 - 2.5e-50 168.1 24.0 2.2e-17 62.8 4.8 3.1 3 0 0 3 3 3 3 Tau and MAP protein, tubulin-binding repeat YkpC PF17447.2 KFR05431.1 - 0.059 14.1 0.6 0.46 11.4 0.1 2.7 3 0 0 3 3 3 0 Uncharacterized YkpC-like PRY PF13765.6 KFR05434.1 - 2.5e-19 68.7 0.0 4.2e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 SPRY-associated domain zf-C2H2 PF00096.26 KFR05435.1 - 1.2e-12 47.6 6.7 1e-06 28.9 0.8 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFR05435.1 - 1.4e-09 37.9 0.4 1.4e-09 37.9 0.4 2.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR05435.1 - 5.1e-09 36.2 5.8 0.0001 22.8 0.8 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFR05435.1 - 0.00083 19.4 0.7 0.0046 17.0 0.7 1.9 1 1 0 1 1 1 1 Zinc ribbon domain zf-C2H2_jaz PF12171.8 KFR05435.1 - 0.001 19.3 1.4 0.18 12.1 0.1 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFR05435.1 - 0.002 18.1 7.3 0.11 12.6 2.2 2.5 2 1 0 2 2 2 2 C2H2-type zinc finger YhfH PF14149.6 KFR05435.1 - 0.0022 17.9 0.3 0.55 10.3 0.1 2.1 2 0 0 2 2 2 1 YhfH-like protein DZR PF12773.7 KFR05435.1 - 0.0083 16.1 0.3 0.01 15.8 0.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon DUF2256 PF10013.9 KFR05435.1 - 0.0098 16.0 1.5 0.75 10.0 0.2 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2256) DUF3268 PF11672.8 KFR05435.1 - 0.011 16.0 0.3 0.012 15.9 0.3 1.1 1 0 0 1 1 1 0 zinc-finger-containing domain zf-LYAR PF08790.11 KFR05435.1 - 0.014 15.3 2.0 1.2 9.1 0.1 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2HE PF16278.5 KFR05435.1 - 0.015 15.8 4.7 0.54 10.8 2.1 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-FCS PF06467.14 KFR05435.1 - 0.02 14.8 0.8 0.38 10.7 0.1 2.1 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DNA_RNApol_7kD PF03604.13 KFR05435.1 - 0.026 14.2 0.9 2.8 7.7 0.4 2.2 1 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit C1_1 PF00130.22 KFR05435.1 - 0.034 14.1 0.4 0.29 11.1 0.3 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2072 PF09845.9 KFR05435.1 - 0.044 14.0 1.4 3.4 7.9 0.2 2.0 2 0 0 2 2 2 0 Zn-ribbon containing protein Ogr_Delta PF04606.12 KFR05435.1 - 0.046 13.7 0.4 0.093 12.7 0.4 1.7 1 1 0 1 1 1 0 Ogr/Delta-like zinc finger zf_UBZ PF18439.1 KFR05435.1 - 0.068 12.8 1.1 0.25 10.9 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-ribbon_3 PF13248.6 KFR05435.1 - 0.07 12.6 2.5 4 7.0 0.6 2.1 2 0 0 2 2 2 0 zinc-ribbon domain HNH PF01844.23 KFR05435.1 - 0.086 13.0 3.1 2.7 8.2 0.2 2.2 2 0 0 2 2 2 0 HNH endonuclease TF_Zn_Ribbon PF08271.12 KFR05435.1 - 0.1 12.1 1.1 1.1 8.8 0.1 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding XPA_N PF01286.18 KFR05435.1 - 0.1 12.7 2.0 1.7 8.7 0.1 2.1 2 0 0 2 2 2 0 XPA protein N-terminal TFIIS_C PF01096.18 KFR05435.1 - 0.12 12.2 3.3 0.81 9.6 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DUF2688 PF10892.8 KFR05435.1 - 0.13 11.8 1.2 4.8 6.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) zf-AN1 PF01428.16 KFR05435.1 - 0.13 12.4 4.4 0.67 10.2 0.1 2.3 2 0 0 2 2 2 0 AN1-like Zinc finger zf-met PF12874.7 KFR05435.1 - 0.15 12.5 1.6 0.18 12.2 0.2 1.8 2 1 0 2 2 2 0 Zinc-finger of C2H2 type Zn_Tnp_IS1595 PF12760.7 KFR05435.1 - 0.2 11.7 3.4 0.33 11.0 3.4 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C2H2_11 PF16622.5 KFR05435.1 - 0.34 10.7 0.1 0.34 10.7 0.1 2.6 3 0 0 3 3 2 0 zinc-finger C2H2-type zinc_ribbon_2 PF13240.6 KFR05435.1 - 0.38 10.5 5.1 6 6.7 0.4 2.1 2 0 0 2 2 2 0 zinc-ribbon domain A2L_zn_ribbon PF08792.10 KFR05435.1 - 0.54 10.0 4.2 6.7 6.5 0.2 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain BTB PF00651.31 KFR05455.1 - 2.5e-29 101.8 1.1 5.3e-29 100.7 1.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFR05455.1 - 5e-08 33.0 13.3 2.7e-07 30.7 2.8 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR05455.1 - 0.004 17.9 18.8 0.13 13.2 4.5 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger DUF3342 PF11822.8 KFR05455.1 - 0.005 17.0 0.7 0.014 15.6 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) zf-C2H2 PF00096.26 KFR05455.1 - 0.0062 16.9 2.4 0.0062 16.9 2.4 3.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type Rota_NS35 PF02509.14 KFR05455.1 - 0.07 12.1 0.1 0.13 11.2 0.1 1.4 1 0 0 1 1 1 0 Rotavirus non-structural protein 35 zf-C2H2_3rep PF18868.1 KFR05455.1 - 0.36 11.5 7.6 0.6 10.8 0.5 3.6 2 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats Vasculin PF15337.6 KFR05468.1 - 5.3e-42 142.6 4.4 5.3e-42 142.6 4.4 2.9 3 0 0 3 3 3 1 Vascular protein family Vasculin-like 1 Laminin_EGF PF00053.24 KFR05469.1 - 6.5e-44 147.9 331.3 0.00069 19.7 20.4 18.8 6 4 12 18 18 18 15 Laminin EGF domain hEGF PF12661.7 KFR05469.1 - 3e-26 91.1 263.2 6.6e-05 23.4 7.0 22.2 22 1 0 22 22 22 16 Human growth factor-like EGF EGF_2 PF07974.13 KFR05469.1 - 2.7e-09 37.2 386.0 0.00037 20.8 18.4 26.2 22 8 4 26 26 26 12 EGF-like domain EGF PF00008.27 KFR05469.1 - 2.7e-05 24.4 330.6 0.005 17.1 15.6 23.3 24 1 0 24 24 24 12 EGF-like domain Baculo_11_kDa PF06143.11 KFR05469.1 - 0.02 14.5 0.7 0.034 13.7 0.7 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family Syndecan PF01034.20 KFR05469.1 - 0.049 13.6 2.5 0.099 12.6 2.5 1.4 1 0 0 1 1 1 0 Syndecan domain DUF836 PF05768.14 KFR05470.1 - 1.8e-14 53.9 0.2 2.2e-14 53.6 0.2 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KFR05470.1 - 0.00027 21.1 0.1 0.00039 20.6 0.1 1.4 1 1 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 KFR05470.1 - 0.0017 18.7 0.1 0.0017 18.7 0.1 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFR05470.1 - 0.017 15.3 0.1 0.061 13.5 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin-like BEX PF04538.12 KFR05470.1 - 0.075 13.6 0.0 0.47 11.0 0.0 1.8 1 1 0 1 1 1 0 Brain expressed X-linked like family RINGv PF12906.7 KFR05471.1 - 1.7e-15 56.9 9.8 3.9e-15 55.7 9.8 1.7 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KFR05471.1 - 0.0022 18.3 9.7 0.0022 18.3 9.7 1.7 2 0 0 2 2 2 1 Ring finger domain Baculo_IE-1 PF05290.11 KFR05471.1 - 0.012 15.6 0.4 0.019 15.0 0.4 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Vpu PF00558.19 KFR05471.1 - 0.054 13.3 0.3 0.097 12.5 0.3 1.3 1 0 0 1 1 1 0 Vpu protein zf-C3HC4 PF00097.25 KFR05471.1 - 0.11 12.4 5.7 0.44 10.5 5.7 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KFR05471.1 - 8 6.7 9.5 1.6 8.9 4.7 2.3 2 1 1 3 3 3 0 FANCL C-terminal domain Filament PF00038.21 KFR05472.1 - 2e-67 228.0 40.4 3.8e-67 227.1 40.4 1.5 1 0 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 KFR05472.1 - 1.3e-18 67.4 0.7 2.6e-18 66.4 0.7 1.5 1 0 0 1 1 1 1 Lamin Tail Domain FlaC_arch PF05377.11 KFR05472.1 - 0.14 12.6 13.6 0.87 10.0 0.1 4.3 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 KFR05472.1 - 0.83 8.5 38.2 1.6 7.5 7.4 3.2 1 1 0 2 2 2 0 Spc7 kinetochore protein PspB PF06667.12 KFR05472.1 - 0.87 9.7 7.4 0.25 11.4 1.5 2.7 2 0 0 2 2 2 0 Phage shock protein B NYD-SP28_assoc PF14775.6 KFR05472.1 - 1.1 9.4 8.0 8.4 6.6 3.5 3.5 2 1 1 3 3 3 0 Sperm tail C-terminal domain Baculo_PEP_C PF04513.12 KFR05472.1 - 1.4 9.0 8.2 9.2 6.3 1.0 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DIT1_PvcA PF05141.12 KFR05472.1 - 2.4 7.6 13.6 1.3 8.4 11.1 1.8 1 1 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein CENP-F_leu_zip PF10473.9 KFR05472.1 - 2.8 7.9 47.7 0.099 12.7 22.1 3.4 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 KFR05472.1 - 2.8 7.9 18.0 0.86 9.6 1.1 3.0 2 1 0 2 2 2 0 Laminin Domain II Tho2 PF11262.8 KFR05472.1 - 3.3 6.8 21.6 0.94 8.6 8.9 2.4 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF5344 PF17279.2 KFR05472.1 - 3.3 8.3 14.2 0.45 11.1 3.9 3.9 2 2 2 4 4 4 0 Family of unknown function (DUF5344) DUF1664 PF07889.12 KFR05472.1 - 9.2 6.3 18.0 12 6.0 2.9 3.9 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Ank_5 PF13857.6 KFR05524.1 - 6.7e-07 29.5 0.0 5.6e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFR05524.1 - 8.2e-07 29.5 0.2 0.00081 19.9 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFR05524.1 - 7.2e-06 26.0 1.0 0.046 14.3 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KFR05524.1 - 3e-05 24.5 0.2 0.033 14.8 0.3 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFR05524.1 - 0.0026 18.1 0.0 0.0026 18.1 0.0 2.9 4 0 0 4 4 4 1 Ankyrin repeat ALMS_repeat PF18727.1 KFR05524.1 - 0.022 14.6 0.5 0.63 10.0 0.0 2.4 2 0 0 2 2 2 0 Alstrom syndrome repeat Yippee-Mis18 PF03226.14 KFR05525.1 - 3.6e-14 52.8 0.1 4.3e-14 52.6 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SelR PF01641.18 KFR05525.1 - 0.0011 19.1 0.0 0.0014 18.7 0.0 1.2 1 0 0 1 1 1 1 SelR domain RIG-I_C-RD PF11648.8 KFR05525.1 - 0.0015 18.8 0.1 0.0021 18.3 0.1 1.2 1 0 0 1 1 1 1 C-terminal domain of RIG-I HNH_5 PF14279.6 KFR05525.1 - 0.0031 17.3 0.2 0.041 13.7 0.0 2.2 2 0 0 2 2 2 1 HNH endonuclease Endonuclease_7 PF02945.15 KFR05525.1 - 0.0082 16.0 0.7 0.042 13.8 0.4 2.0 1 1 1 2 2 2 1 Recombination endonuclease VII HECT_2 PF09814.9 KFR05525.1 - 0.072 11.9 0.9 0.23 10.3 0.0 1.8 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Sgf11 PF08209.11 KFR05525.1 - 0.19 11.3 2.4 5.9 6.5 0.1 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Lbh PF15317.6 KFR05527.1 - 1.2e-28 99.9 2.8 1.4e-28 99.7 2.8 1.0 1 0 0 1 1 1 1 Cardiac transcription factor regulator, Developmental protein Acyltransferase PF01553.21 KFR05528.1 - 1.8e-23 82.6 0.0 5.5e-23 81.1 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase Acyltransf_C PF16076.5 KFR05528.1 - 1.9e-19 69.5 2.3 3.1e-19 68.8 0.1 2.3 2 0 0 2 2 2 1 Acyltransferase C-terminus Peptidase_C2 PF00648.21 KFR05529.1 - 2.2e-110 368.3 0.1 2.5e-110 368.2 0.1 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease Peptidase_C47 PF05543.13 KFR05529.1 - 0.00011 21.9 0.2 0.00022 20.9 0.2 1.4 1 0 0 1 1 1 1 Staphopain peptidase C47 Glycos_transf_2 PF00535.26 KFR05530.1 - 5.8e-24 84.8 0.0 9.2e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFR05530.1 - 2.3e-20 73.2 3.3 3.8e-20 72.4 3.3 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 KFR05530.1 - 6.5e-07 29.5 0.0 1.1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KFR05530.1 - 4.4e-05 23.1 0.0 0.00025 20.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KFR05530.1 - 0.00046 19.8 0.0 0.00099 18.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Peptidase_C2 PF00648.21 KFR05531.1 - 9.4e-104 346.6 0.1 1.1e-103 346.4 0.1 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease DUF5600 PF18150.1 KFR05532.1 - 3.1e-44 149.9 1.8 3.1e-44 149.9 1.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 KFR05532.1 - 3.5e-19 68.7 0.2 1.8e-18 66.4 0.0 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EHD_N PF16880.5 KFR05532.1 - 2.4e-18 65.7 4.5 5.5e-18 64.6 4.5 1.7 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 KFR05532.1 - 8.9e-13 48.6 0.0 5.6e-12 46.0 0.0 2.1 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KFR05532.1 - 3.5e-09 36.7 0.0 8.6e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 KFR05532.1 - 0.00065 19.1 0.8 0.0025 17.2 0.2 2.4 2 0 0 2 2 1 1 EF hand GTP_EFTU PF00009.27 KFR05532.1 - 0.006 16.1 0.1 0.088 12.3 0.2 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 KFR05532.1 - 0.0079 16.4 0.0 1.5 9.0 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KFR05532.1 - 0.013 14.9 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AIG1 PF04548.16 KFR05532.1 - 0.014 14.7 0.0 0.081 12.2 0.0 2.2 3 0 0 3 3 3 0 AIG1 family AAA_28 PF13521.6 KFR05532.1 - 0.035 14.3 0.0 0.16 12.2 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.6 KFR05532.1 - 0.047 14.1 0.2 0.31 11.4 0.0 2.4 2 2 0 2 2 2 0 AAA ATPase domain EF-hand_7 PF13499.6 KFR05532.1 - 0.1 13.1 0.1 0.44 11.0 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair cobW PF02492.19 KFR05532.1 - 0.14 11.8 0.0 20 4.7 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 KFR05532.1 - 0.16 12.0 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE EF-hand_8 PF13833.6 KFR05532.1 - 0.38 10.6 2.0 0.84 9.5 0.3 2.3 2 0 0 2 2 2 0 EF-hand domain pair Ald_Xan_dh_C2 PF02738.18 KFR05533.1 - 4.4e-207 688.9 0.0 6.5e-207 688.3 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KFR05533.1 - 5.5e-54 182.5 0.0 1e-53 181.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 KFR05533.1 - 2.6e-37 127.6 1.4 4.1e-37 126.9 0.7 1.8 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 KFR05533.1 - 9.3e-33 112.5 0.0 2.7e-32 111.0 0.0 1.8 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 KFR05533.1 - 5.9e-30 103.1 0.1 1.4e-29 101.9 0.1 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 KFR05533.1 - 3.5e-09 36.5 3.0 8.6e-09 35.2 0.4 2.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.17 KFR05533.1 - 0.11 12.5 0.0 0.39 10.8 0.0 1.9 1 0 0 1 1 1 0 DUF218 domain CNH PF00780.22 KFR05534.1 - 2.1e-77 260.5 0.1 4e-77 259.5 0.1 1.5 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.25 KFR05534.1 - 3.4e-55 187.3 0.0 1.2e-54 185.5 0.0 2.0 1 0 0 1 1 1 1 Protein kinase domain KELK PF15796.5 KFR05534.1 - 1.3e-32 112.1 20.6 1.3e-32 112.1 20.6 7.5 5 3 2 7 7 5 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pkinase_Tyr PF07714.17 KFR05534.1 - 3.2e-29 102.0 0.0 9.7e-29 100.4 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase DMPK_coil PF08826.10 KFR05534.1 - 2.1e-25 88.6 11.2 2.1e-25 88.6 11.2 9.3 7 4 2 10 10 9 2 DMPK coiled coil domain like C1_1 PF00130.22 KFR05534.1 - 2.2e-11 43.5 8.1 2.2e-11 43.5 8.1 2.0 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 KFR05534.1 - 4.9e-07 29.3 0.0 1.6e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 KFR05534.1 - 6.8e-05 23.5 3.2 9.3e-05 23.0 1.6 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain PBD PF00786.28 KFR05534.1 - 0.011 16.1 0.1 0.075 13.4 0.0 2.6 2 0 0 2 2 2 0 P21-Rho-binding domain Seadorna_VP7 PF07387.11 KFR05534.1 - 0.061 12.4 0.3 0.16 11.0 0.3 1.6 1 0 0 1 1 1 0 Seadornavirus VP7 Calici_MSP PF05752.11 KFR05534.1 - 1 9.2 5.1 3.6 7.4 4.6 2.2 1 1 0 1 1 1 0 Calicivirus minor structural protein ABC1 PF03109.16 KFR05535.1 - 2.1e-33 115.0 0.0 4e-33 114.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family DUF2959 PF11172.8 KFR05535.1 - 0.033 14.3 0.2 0.18 12.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) Presenilin PF01080.17 KFR05536.1 - 1.1e-159 531.6 15.5 1.8e-112 376.0 12.2 2.3 2 1 1 3 3 3 2 Presenilin DUF4643 PF15485.6 KFR05536.1 - 0.024 14.5 0.9 0.044 13.6 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) IPK PF03770.16 KFR05537.1 - 5.6e-45 153.6 0.0 1.2e-44 152.6 0.0 1.5 1 1 0 1 1 1 1 Inositol polyphosphate kinase Retrotrans_gag PF03732.17 KFR05537.1 - 0.02 15.2 1.0 0.65 10.3 0.0 2.7 2 0 0 2 2 2 0 Retrotransposon gag protein Spec3 PF15795.5 KFR05538.1 - 6.9e-16 58.6 7.0 7.4e-16 58.5 7.0 1.0 1 0 0 1 1 1 1 Ectodermal ciliogenesis protein NrsF PF06532.11 KFR05538.1 - 0.0025 17.6 3.2 0.003 17.3 3.2 1.1 1 0 0 1 1 1 1 Negative regulator of sigma F Phage_holin_3_6 PF07332.11 KFR05538.1 - 3.5 7.7 7.4 4 7.5 7.4 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III zf-PARP PF00645.18 KFR05539.1 - 2.8e-13 50.5 8.1 3.1e-07 31.1 0.3 2.2 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DIRP PF06584.13 KFR05540.1 - 2.6e-47 159.4 0.3 7.3e-47 157.9 0.3 1.8 1 0 0 1 1 1 1 DIRP DUF2664 PF10867.8 KFR05540.1 - 0.017 15.5 0.3 0.054 14.0 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2664) FTA4 PF13093.6 KFR05540.1 - 0.025 14.5 3.7 0.068 13.1 3.7 2.0 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 GOLD_2 PF13897.6 KFR05541.1 - 8.7e-72 240.1 4.7 8.7e-72 240.1 4.7 3.1 2 1 0 2 2 2 1 Golgi-dynamics membrane-trafficking ACBP PF00887.19 KFR05541.1 - 1.5e-13 50.8 0.0 5.2e-13 49.0 0.0 2.0 1 0 0 1 1 1 1 Acyl CoA binding protein Merozoite_SPAM PF07133.11 KFR05541.1 - 1.4 8.9 31.2 0.45 10.5 18.2 2.3 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) RR_TM4-6 PF06459.12 KFR05541.1 - 5.8 6.7 28.9 0.77 9.5 18.6 2.7 2 1 1 3 3 3 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 KFR05541.1 - 5.9 5.8 13.4 2.9 6.8 7.3 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) RNA_polI_A34 PF08208.11 KFR05541.1 - 7.7 6.6 19.9 13 5.9 0.2 2.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Histone PF00125.24 KFR05542.1 - 1.2e-43 148.6 0.4 1.3e-43 148.5 0.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KFR05542.1 - 4.4e-05 23.5 0.0 5.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KFR05542.1 - 0.00012 22.4 0.0 0.00015 22.0 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KFR05542.1 - 0.028 14.7 0.0 0.038 14.3 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFR05542.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Sde2_N_Ubi PF13019.6 KFR05543.1 - 3.7e-16 59.4 2.1 4.8e-16 59.0 2.1 1.3 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Exonuc_VII_L PF02601.15 KFR05543.1 - 0.0094 15.6 1.4 0.0098 15.5 1.4 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit ARGLU PF15346.6 KFR05543.1 - 0.016 15.1 7.2 0.022 14.6 7.2 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Tmemb_cc2 PF10267.9 KFR05543.1 - 0.016 14.3 2.2 0.022 13.9 2.2 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein TGFb_propeptide PF00688.18 KFR05544.1 - 1.1e-18 67.9 0.5 2.8e-17 63.3 0.1 2.0 2 0 0 2 2 2 2 TGF-beta propeptide TGF_beta PF00019.20 KFR05544.1 - 7.3e-14 52.6 4.9 1.6e-12 48.3 4.9 2.4 1 1 0 1 1 1 1 Transforming growth factor beta like domain RSN1_7TM PF02714.15 KFR05545.1 - 3.7e-59 200.3 26.5 3.7e-59 200.3 26.5 3.3 3 1 1 4 4 4 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KFR05545.1 - 6.1e-45 153.6 1.0 9.6e-45 152.9 1.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KFR05545.1 - 1.4e-21 76.9 0.9 1.4e-21 76.9 0.9 4.9 4 1 0 5 5 5 2 Late exocytosis, associated with Golgi transport RRM_1 PF00076.22 KFR05545.1 - 0.00068 19.4 0.0 0.23 11.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EHN PF06441.12 KFR05546.1 - 6.7e-32 110.1 0.4 1.1e-31 109.3 0.4 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KFR05546.1 - 2.4e-19 70.0 0.0 6e-19 68.7 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFR05546.1 - 0.00022 21.9 0.4 0.16 12.6 0.1 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family SRP9-21 PF05486.12 KFR05547.1 - 1.3e-06 28.7 0.1 2.1e-06 28.0 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) WH1 PF00568.23 KFR05548.1 - 7.3e-40 135.4 0.2 1e-39 134.9 0.2 1.2 1 0 0 1 1 1 1 WH1 domain VASP_tetra PF08776.11 KFR05548.1 - 6.7e-18 64.0 3.3 1.5e-17 62.8 3.3 1.7 1 0 0 1 1 1 1 VASP tetramerisation domain GBP_C PF02841.14 KFR05548.1 - 9.9 5.5 27.0 22 4.3 27.0 1.6 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain ERG4_ERG24 PF01222.17 KFR05549.1 - 4.6e-186 618.7 11.2 5.6e-186 618.5 11.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family LBR_tudor PF09465.10 KFR05549.1 - 6.6e-31 105.9 0.5 1.3e-30 105.0 0.5 1.5 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain DUF1295 PF06966.12 KFR05549.1 - 1.3e-06 28.1 0.3 4e-06 26.5 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KFR05549.1 - 0.00049 20.5 1.2 0.0018 18.6 0.1 2.5 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 KFR05549.1 - 0.0025 18.2 0.3 0.0025 18.2 0.3 2.3 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Corona_nucleoca PF00937.18 KFR05549.1 - 0.0057 15.7 5.7 0.0087 15.1 5.7 1.2 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein MAJIN PF15077.6 KFR05549.1 - 0.023 14.5 1.1 0.048 13.4 1.1 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF2207 PF09972.9 KFR05549.1 - 0.085 11.6 0.0 0.085 11.6 0.0 2.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) FoP_duplication PF13865.6 KFR05549.1 - 3.3 8.3 8.1 5.9 7.5 8.1 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Cornichon PF03311.14 KFR05552.1 - 2e-42 144.4 2.5 2.3e-42 144.2 2.5 1.0 1 0 0 1 1 1 1 Cornichon protein DUF2650 PF10853.8 KFR05552.1 - 0.47 10.2 3.6 2.5 7.9 3.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2650) AAA PF00004.29 KFR05553.1 - 7.5e-93 307.9 0.0 1.4e-47 161.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFR05553.1 - 1.6e-25 88.6 0.3 1.2e-11 44.3 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain Nucleolin_bd PF16725.5 KFR05553.1 - 1.2e-21 76.1 0.1 2.8e-21 74.9 0.1 1.6 1 0 0 1 1 1 1 Nucleolin binding domain RuvB_N PF05496.12 KFR05553.1 - 9.8e-14 51.4 0.0 7.6e-06 25.8 0.0 3.0 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFR05553.1 - 4.5e-12 46.7 5.2 0.015 15.7 0.1 5.5 3 2 2 5 5 5 2 AAA ATPase domain AAA_2 PF07724.14 KFR05553.1 - 9.6e-12 45.3 0.0 0.0001 22.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFR05553.1 - 2.9e-11 43.8 2.9 0.05 13.9 0.0 5.0 3 2 2 5 5 4 3 AAA domain AAA_5 PF07728.14 KFR05553.1 - 3.2e-10 40.1 1.9 8.7e-05 22.5 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KFR05553.1 - 5.5e-09 35.7 0.1 0.0043 16.3 0.0 2.7 2 1 1 3 3 3 2 TIP49 P-loop domain AAA_33 PF13671.6 KFR05553.1 - 1.6e-08 34.8 0.1 0.0044 17.2 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.6 KFR05553.1 - 2.5e-08 34.0 0.0 0.011 15.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KFR05553.1 - 1e-07 31.5 0.2 0.0071 15.7 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KFR05553.1 - 3.2e-07 30.7 0.0 0.014 15.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KFR05553.1 - 7.4e-07 29.5 0.0 0.098 13.1 0.0 3.0 2 1 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 KFR05553.1 - 9e-07 29.5 0.0 0.02 15.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KFR05553.1 - 9.8e-07 28.7 0.0 0.046 13.5 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.12 KFR05553.1 - 2.8e-06 26.8 0.5 0.0035 16.6 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin TsaE PF02367.17 KFR05553.1 - 3e-06 27.3 0.0 0.057 13.4 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 KFR05553.1 - 3.7e-06 26.9 0.0 0.092 12.5 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 KFR05553.1 - 6.9e-06 26.1 0.1 0.11 12.4 0.0 2.8 2 1 1 3 3 3 2 Rad17 P-loop domain AAA_17 PF13207.6 KFR05553.1 - 7.6e-06 26.4 0.0 0.2 12.0 0.0 3.3 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 KFR05553.1 - 7.7e-06 25.8 0.6 0.17 11.9 0.1 3.0 3 0 0 3 3 2 2 Vps4 C terminal oligomerisation domain NACHT PF05729.12 KFR05553.1 - 8.9e-06 25.7 1.0 0.054 13.4 0.1 3.1 2 1 0 2 2 2 2 NACHT domain AAA_3 PF07726.11 KFR05553.1 - 2.1e-05 24.4 0.0 0.15 12.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.6 KFR05553.1 - 2.4e-05 24.5 0.0 0.028 14.5 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family ATPase PF06745.13 KFR05553.1 - 3.1e-05 23.4 1.9 0.68 9.2 0.0 4.1 3 1 1 4 4 3 2 KaiC ABC_tran PF00005.27 KFR05553.1 - 6.6e-05 23.4 1.0 0.63 10.6 0.0 3.5 4 1 0 4 4 2 2 ABC transporter Sigma54_activat PF00158.26 KFR05553.1 - 0.00034 20.4 0.0 0.41 10.3 0.0 3.3 2 1 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 KFR05553.1 - 0.00043 20.4 0.0 0.96 9.6 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain NB-ARC PF00931.22 KFR05553.1 - 0.00044 19.5 0.0 1.3 8.1 0.0 2.8 3 0 0 3 3 3 2 NB-ARC domain DUF2075 PF09848.9 KFR05553.1 - 0.00056 19.3 0.0 1.9 7.6 0.0 3.4 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 KFR05553.1 - 0.001 18.7 4.9 1.7 8.2 0.2 3.6 2 2 2 4 4 4 2 AAA domain PhoH PF02562.16 KFR05553.1 - 0.0028 17.2 0.4 1.5 8.2 0.0 2.7 3 0 0 3 3 3 1 PhoH-like protein AAA_7 PF12775.7 KFR05553.1 - 0.0036 16.8 0.1 2.8 7.4 0.0 2.7 2 1 0 2 2 2 1 P-loop containing dynein motor region SKI PF01202.22 KFR05553.1 - 0.006 16.7 0.0 2.5 8.2 0.0 3.1 3 0 0 3 3 2 1 Shikimate kinase DUF815 PF05673.13 KFR05553.1 - 0.0067 15.6 0.0 0.23 10.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 KFR05553.1 - 0.008 15.3 0.0 2.7 7.0 0.0 2.6 3 0 0 3 3 3 1 Parvovirus non-structural protein NS1 PduV-EutP PF10662.9 KFR05553.1 - 0.01 15.6 0.0 6 6.6 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KFR05553.1 - 0.017 15.0 0.0 6.3 6.7 0.0 3.1 2 1 1 3 3 3 0 NTPase AAA_24 PF13479.6 KFR05553.1 - 0.021 14.5 0.0 4.7 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KFR05553.1 - 0.047 14.0 1.4 11 6.3 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFR05553.1 - 0.05 13.3 0.1 7 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KFR05553.1 - 0.051 13.5 1.8 11 5.8 0.0 3.9 3 2 2 5 5 5 0 ATPase domain predominantly from Archaea Cytidylate_kin PF02224.18 KFR05553.1 - 0.097 12.4 0.4 15 5.2 0.1 2.6 2 0 0 2 2 2 0 Cytidylate kinase AAA_11 PF13086.6 KFR05553.1 - 0.1 12.4 6.2 2.3 7.9 0.0 3.1 3 1 0 3 3 2 0 AAA domain Zot PF05707.12 KFR05553.1 - 0.1 12.2 0.1 5 6.7 0.0 3.1 2 2 1 3 3 3 0 Zonular occludens toxin (Zot) FA_desaturase PF00487.24 KFR05554.1 - 6e-25 88.5 14.8 6e-25 88.5 14.8 1.6 2 0 0 2 2 2 1 Fatty acid desaturase Lipid_DES PF08557.10 KFR05554.1 - 0.0021 17.5 0.2 0.0043 16.5 0.2 1.6 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) ATG16 PF08614.11 KFR05555.1 - 1.6e-05 25.3 2.9 1.6e-05 25.3 2.9 1.7 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) FAM76 PF16046.5 KFR05555.1 - 0.00012 21.6 1.7 0.00023 20.6 1.7 1.6 1 0 0 1 1 1 1 FAM76 protein Filament PF00038.21 KFR05555.1 - 0.0038 16.9 7.5 0.0076 15.9 7.5 1.4 1 0 0 1 1 1 1 Intermediate filament protein SlyX PF04102.12 KFR05555.1 - 0.018 15.7 10.1 0.018 15.7 10.1 2.9 2 1 1 3 3 3 0 SlyX DUF16 PF01519.16 KFR05555.1 - 0.026 15.0 3.8 0.026 15.0 3.8 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 Spc7 PF08317.11 KFR05555.1 - 0.027 13.4 10.8 0.047 12.6 10.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 KFR05555.1 - 0.029 14.4 11.7 0.4 10.7 4.4 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding FmiP_Thoc5 PF09766.9 KFR05555.1 - 0.033 13.5 7.0 0.05 12.9 7.0 1.2 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 DUF3450 PF11932.8 KFR05555.1 - 0.073 12.4 9.3 0.17 11.1 9.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3287 PF11690.8 KFR05555.1 - 0.091 12.5 6.5 0.083 12.6 2.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3287) DUF4407 PF14362.6 KFR05555.1 - 0.11 11.8 4.0 0.18 11.1 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2730 PF10805.8 KFR05555.1 - 0.21 11.7 3.1 1.7 8.8 3.1 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) SKA1 PF07160.12 KFR05555.1 - 0.23 11.3 8.3 0.5 10.2 8.3 1.6 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF724 PF05266.14 KFR05555.1 - 0.25 11.1 4.9 0.52 10.1 4.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Fez1 PF06818.15 KFR05555.1 - 0.29 11.5 14.2 0.083 13.3 10.7 1.8 2 0 0 2 2 2 0 Fez1 HemX PF04375.14 KFR05555.1 - 0.33 10.2 9.6 0.7 9.1 9.6 1.5 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase OmpH PF03938.14 KFR05555.1 - 0.94 9.8 13.8 0.88 9.9 11.9 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) COG2 PF06148.11 KFR05555.1 - 1.1 9.3 6.4 3.2 7.8 3.5 2.7 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FlaC_arch PF05377.11 KFR05555.1 - 1.8 9.0 4.8 1.3 9.4 1.9 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) ABC_tran_CTD PF16326.5 KFR05555.1 - 2.2 8.6 11.9 14 6.1 11.9 2.3 1 1 0 1 1 1 0 ABC transporter C-terminal domain YabA PF06156.13 KFR05555.1 - 2.6 8.7 8.7 9.6 6.9 5.9 2.5 1 1 1 2 2 2 0 Initiation control protein YabA NPV_P10 PF05531.12 KFR05555.1 - 3.8 8.0 9.5 11 6.5 7.6 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FliD_N PF02465.18 KFR05555.1 - 4 8.2 7.3 6 7.6 2.7 2.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus TMF_TATA_bd PF12325.8 KFR05555.1 - 4.9 7.4 14.3 2.9 8.1 11.2 2.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Exonuc_VII_L PF02601.15 KFR05555.1 - 8.4 5.9 13.9 1.3 8.6 8.8 1.9 1 1 1 2 2 2 0 Exonuclease VII, large subunit Peptidase_C2 PF00648.21 KFR05556.1 - 1.5e-129 431.3 0.1 2.8e-129 430.4 0.0 1.5 2 0 0 2 2 2 1 Calpain family cysteine protease Calpain_III PF01067.22 KFR05556.1 - 2.2e-51 173.9 0.0 3.2e-50 170.1 0.0 2.2 2 0 0 2 2 2 1 Calpain large subunit, domain III EF-hand_6 PF13405.6 KFR05556.1 - 1.3e-10 40.4 0.2 0.0054 16.6 0.0 4.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 KFR05556.1 - 1.4e-10 39.9 0.1 0.018 14.5 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 KFR05556.1 - 0.0005 20.5 0.1 0.41 11.1 0.1 3.6 2 2 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KFR05556.1 - 0.0029 17.0 0.0 4.5 6.9 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KFR05556.1 - 0.0077 16.1 1.0 0.39 10.6 0.0 3.8 3 1 0 3 3 3 1 EF-hand domain pair Ndufs5 PF10200.9 KFR05556.1 - 0.021 15.1 0.0 2.6 8.4 0.0 2.6 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF4300 PF14133.6 KFR05556.1 - 0.044 13.5 0.2 0.079 12.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4300) Alpha_adaptin_C PF02296.16 KFR05556.1 - 0.13 12.5 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain RAMA PF18755.1 KFR05580.1 - 2.3e-15 57.0 0.1 6.3e-15 55.5 0.1 1.7 1 0 0 1 1 1 1 Restriction Enzyme Adenine Methylase Associated Ank_4 PF13637.6 KFR05580.1 - 0.014 16.0 0.0 0.048 14.3 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFR05580.1 - 0.071 13.4 0.0 1.1 9.6 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Homeodomain PF00046.29 KFR05613.1 - 1.4e-15 56.9 0.5 2.4e-15 56.1 0.5 1.4 1 0 0 1 1 1 1 Homeodomain EF-hand_13 PF17958.1 KFR05614.1 - 7.8e-44 147.4 0.1 8.5e-42 140.9 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KFR05614.1 - 2.2e-22 79.3 6.6 1.2e-20 73.7 2.3 4.0 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KFR05614.1 - 1.9e-08 33.3 0.2 0.073 12.7 0.0 6.0 6 0 0 6 6 6 2 EF hand EF-hand_8 PF13833.6 KFR05614.1 - 5.1e-07 29.4 0.2 0.46 10.4 0.0 6.1 6 0 0 6 6 6 1 EF-hand domain pair EF-hand_6 PF13405.6 KFR05614.1 - 8e-07 28.5 3.2 0.034 14.1 0.0 6.1 7 0 0 7 7 7 1 EF-hand domain EF-hand_5 PF13202.6 KFR05614.1 - 1.5e-06 27.4 0.1 0.0005 19.4 0.0 4.3 5 0 0 5 5 5 1 EF hand SPARC_Ca_bdg PF10591.9 KFR05614.1 - 0.047 14.0 5.2 2.5 8.4 0.3 3.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SBP_bac_6 PF13343.6 KFR05614.1 - 0.075 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein STAG PF08514.11 KFR05615.1 - 2.3e-34 117.7 0.2 6.8e-34 116.2 0.2 1.9 1 0 0 1 1 1 1 STAG domain AHSP PF09236.10 KFR05615.1 - 0.019 15.4 3.0 2.6 8.6 0.1 3.4 3 0 0 3 3 3 0 Alpha-haemoglobin stabilising protein HEAT PF02985.22 KFR05615.1 - 0.045 14.0 0.0 47 4.6 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat GTP-bdg_M PF16360.5 KFR05616.1 - 2.5e-21 76.0 6.3 5.4e-21 75.0 6.3 1.6 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region GTP-bdg_N PF13167.6 KFR05616.1 - 2.9e-14 53.5 0.7 2.2e-13 50.7 0.1 2.5 2 0 0 2 2 2 1 GTP-binding GTPase N-terminal MMR_HSR1 PF01926.23 KFR05616.1 - 4.6e-13 49.2 0.0 1.5e-12 47.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Rad17 PF03215.15 KFR05616.1 - 0.00031 20.7 0.3 0.14 12.0 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain FeoB_N PF02421.18 KFR05616.1 - 0.00049 19.7 0.7 0.0017 17.9 0.7 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 KFR05616.1 - 0.0035 17.1 0.8 0.073 12.8 0.8 2.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KFR05616.1 - 0.0098 15.8 0.1 4 7.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KFR05616.1 - 0.012 15.6 0.0 0.04 13.9 0.0 1.8 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_16 PF13191.6 KFR05616.1 - 0.013 15.9 0.0 0.031 14.6 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 KFR05616.1 - 0.016 14.8 0.1 2.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MnmE_helical PF12631.7 KFR05616.1 - 0.03 14.5 0.0 0.058 13.6 0.0 1.4 1 1 0 1 1 1 0 MnmE helical domain MobB PF03205.14 KFR05616.1 - 0.031 14.2 0.2 0.21 11.5 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.27 KFR05616.1 - 0.05 14.1 0.9 0.12 12.9 0.1 2.1 1 1 1 2 2 2 0 ABC transporter TniB PF05621.11 KFR05616.1 - 0.059 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein PI-PLC-X PF00388.19 KFR05617.1 - 0.0013 18.3 0.4 0.0029 17.2 0.3 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain SGL PF08450.12 KFR05618.1 - 3.6e-80 269.1 0.0 4.1e-80 268.9 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 KFR05618.1 - 0.068 13.4 0.0 1.2 9.6 0.0 2.9 2 1 0 2 2 2 0 Two component regulator propeller Kelch_6 PF13964.6 KFR05618.1 - 0.5 10.7 3.1 22 5.5 0.0 3.5 3 1 1 4 4 4 0 Kelch motif SGL PF08450.12 KFR05619.1 - 3.7e-78 262.5 0.1 4.2e-78 262.3 0.1 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 KFR05619.1 - 0.025 14.8 0.0 0.33 11.3 0.0 2.9 2 1 0 2 2 2 0 Two component regulator propeller NHL PF01436.21 KFR05619.1 - 0.093 12.8 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 NHL repeat zf-HC5HC2H_2 PF13832.6 KFR05620.1 - 5.1e-30 103.9 7.9 5.1e-30 103.9 7.9 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFR05620.1 - 5.8e-25 87.4 6.1 5.8e-25 87.4 6.1 3.3 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KFR05620.1 - 2.9e-12 45.9 7.0 2.9e-12 45.9 7.0 3.6 4 0 0 4 4 4 1 PHD-finger PHD PF00628.29 KFR05620.1 - 2.2e-10 40.2 9.5 2.2e-10 40.2 9.5 3.5 2 1 0 3 3 3 2 PHD-finger EPL1 PF10513.9 KFR05620.1 - 2.6e-08 34.4 0.3 2.6e-08 34.4 0.3 3.2 4 1 0 4 4 4 1 Enhancer of polycomb-like C1_1 PF00130.22 KFR05620.1 - 0.0014 18.4 2.6 0.0014 18.4 2.6 3.8 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 KFR05620.1 - 0.013 15.5 7.5 0.013 15.5 7.5 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 KFR05620.1 - 0.24 11.0 15.0 4.5 6.9 7.4 3.4 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_2 PF03107.16 KFR05620.1 - 0.59 10.5 23.8 1.3 9.4 7.9 3.6 3 0 0 3 3 3 0 C1 domain TBCC PF07986.12 KFR05621.1 - 2.9e-46 156.1 5.5 4.6e-46 155.4 5.5 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 KFR05621.1 - 0.00042 20.0 3.2 0.00083 19.0 3.2 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal NDK PF00334.19 KFR05621.1 - 0.0014 18.7 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Na_H_Exchanger PF00999.21 KFR05622.1 - 4.9e-85 285.6 26.9 6.1e-85 285.3 26.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3623 PF12291.8 KFR05622.1 - 0.0011 18.3 1.2 0.0011 18.3 1.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3623) GCP_C_terminal PF04130.13 KFR05623.1 - 1.1e-39 136.8 10.4 1.3e-39 136.5 8.9 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KFR05623.1 - 1.8e-27 96.8 2.3 1.8e-27 96.8 2.3 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP5-Mod21 PF14609.6 KFR05623.1 - 0.00043 18.8 2.2 0.00092 17.7 0.1 2.4 3 0 0 3 3 3 1 gamma-Tubulin ring complex non-core subunit mod21 DUF5601 PF18151.1 KFR05623.1 - 0.056 13.8 0.6 1.7 9.0 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) FragX_IP PF05994.11 KFR05624.1 - 0 1329.6 5.8 0 1329.6 5.8 1.7 2 0 0 2 2 2 1 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 KFR05624.1 - 5.7e-08 32.4 6.2 1.4e-07 31.1 6.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) zf-CW PF07496.15 KFR05624.1 - 0.1 12.7 0.4 0.25 11.4 0.4 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger fn3 PF00041.21 KFR05625.1 - 1.9e-05 24.9 0.1 3.3e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III domain MLANA PF14991.6 KFR05625.1 - 0.025 14.8 0.0 0.041 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein melan-A FAM163 PF15069.6 KFR05625.1 - 0.058 13.8 0.4 0.086 13.3 0.0 1.5 2 0 0 2 2 2 0 FAM163 family Pur_ac_phosph_N PF16656.5 KFR05625.1 - 0.061 13.9 0.6 0.08 13.5 0.1 1.5 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Mg_trans_NIPA PF05653.14 KFR05626.1 - 6.9e-148 491.5 16.5 7.9e-148 491.3 16.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KFR05626.1 - 3.2e-09 37.1 4.0 3.2e-09 37.1 4.0 4.2 3 1 0 3 3 3 1 EamA-like transporter family DUF2627 PF11118.8 KFR05626.1 - 0.62 10.7 3.9 13 6.4 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) S1FA PF04689.13 KFR05626.1 - 3.1 8.0 4.9 2 8.6 0.6 2.7 3 0 0 3 3 3 0 DNA binding protein S1FA Mg_trans_NIPA PF05653.14 KFR05627.1 - 2.2e-70 237.1 14.9 2.5e-70 236.9 14.9 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KFR05627.1 - 0.0042 17.3 4.5 0.0042 17.3 4.5 3.2 2 1 1 3 3 3 2 EamA-like transporter family DUF3611 PF12263.8 KFR05627.1 - 0.048 13.5 0.2 0.048 13.5 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3611) Acyl_transf_3 PF01757.22 KFR05627.1 - 0.51 9.4 14.1 0.61 9.1 10.8 2.1 1 1 1 2 2 2 0 Acyltransferase family DUF2973 PF11189.8 KFR05627.1 - 1.4 9.0 3.3 0.49 10.5 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) RCC1 PF00415.18 KFR05628.1 - 1.8e-230 745.6 86.0 2.8e-15 56.7 0.1 21.4 21 0 0 21 21 21 19 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFR05628.1 - 1.2e-88 289.5 109.6 9.2e-08 31.7 0.3 21.9 22 0 0 22 22 22 16 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.25 KFR05628.1 - 4.1e-60 203.9 0.0 7.6e-60 203.0 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Cul7 PF11515.8 KFR05628.1 - 3.4e-35 120.2 2.5 4.4e-35 119.8 0.8 2.1 2 0 0 2 2 2 1 Mouse development and cellular proliferation protein Cullin-7 MIB_HERC2 PF06701.13 KFR05628.1 - 5.5e-22 77.8 5.0 5.5e-22 77.8 5.0 5.7 7 0 0 7 7 7 1 Mib_herc2 Cyt-b5 PF00173.28 KFR05628.1 - 3.3e-10 39.9 0.0 1.2e-09 38.2 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain ZZ PF00569.17 KFR05628.1 - 9e-10 38.2 7.0 2.2e-09 37.0 7.0 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type SH3_15 PF18346.1 KFR05628.1 - 3e-06 27.4 5.0 0.00014 22.1 0.6 3.7 3 0 0 3 3 3 1 Mind bomb SH3 repeat domain ANAPC10 PF03256.16 KFR05628.1 - 4e-06 26.6 0.0 7.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Med3 PF11593.8 KFR05628.1 - 0.049 12.8 0.5 0.12 11.5 0.5 1.6 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Hira PF07569.11 KFR05628.1 - 0.055 13.2 0.6 56 3.4 0.0 5.3 6 0 0 6 6 6 0 TUP1-like enhancer of split Ubie_methyltran PF01209.18 KFR05628.1 - 0.092 12.1 0.7 20 4.4 0.0 3.8 4 0 0 4 4 4 0 ubiE/COQ5 methyltransferase family zf-UBR PF02207.20 KFR05628.1 - 0.45 10.7 5.3 0.22 11.7 2.2 2.1 2 0 0 2 2 1 0 Putative zinc finger in N-recognin (UBR box) CitMHS PF03600.16 KFR05629.1 - 4.1e-57 193.7 18.8 4.1e-57 193.7 18.8 2.2 2 1 1 3 3 3 1 Citrate transporter ArsB PF02040.15 KFR05629.1 - 4.6e-09 36.1 22.8 0.00013 21.4 10.9 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein RAMP4 PF06624.12 KFR05629.1 - 2.6 8.2 4.9 12 6.1 4.0 2.3 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 DUF4491 PF14898.6 KFR05629.1 - 10 6.7 7.9 3.2 8.3 2.3 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) Neur_chan_memb PF02932.16 KFR05630.1 - 6.4e-38 131.1 9.8 9.7e-35 120.7 6.2 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFR05630.1 - 4e-37 127.7 3.0 5.5e-37 127.3 3.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF2070 PF09843.9 KFR05630.1 - 1.6 6.9 4.8 2.2 6.4 4.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) YesK PF14150.6 KFR05630.1 - 1.8 8.8 5.2 11 6.3 0.8 3.1 2 1 1 3 3 3 0 YesK-like protein Neur_chan_LBD PF02931.23 KFR05631.1 - 3.1e-49 167.3 0.0 4.4e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFR05631.1 - 4.6e-39 134.9 3.6 5.1e-33 115.1 2.0 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region CytochromB561_N PF09786.9 KFR05631.1 - 0.00039 19.5 1.1 0.00054 19.1 1.1 1.1 1 0 0 1 1 1 1 Cytochrome B561, N terminal Neur_chan_memb PF02932.16 KFR05632.1 - 5.4e-51 174.0 0.4 1e-50 173.0 0.4 1.4 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFR05632.1 - 2.9e-38 131.5 0.0 4.5e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain OAD_gamma PF04277.13 KFR05632.1 - 0.071 13.7 0.2 0.16 12.6 0.0 1.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain PhoLip_ATPase_C PF16212.5 KFR05633.1 - 1e-78 264.5 24.1 1e-78 264.5 24.1 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFR05633.1 - 5.1e-19 67.7 3.4 1.7e-18 66.1 3.4 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFR05633.1 - 3.1e-12 47.2 0.0 1.2e-05 25.7 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFR05633.1 - 8.8e-09 35.3 0.0 8.8e-08 32.1 0.0 2.6 2 1 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFR05633.1 - 3.7e-06 26.6 0.0 3.7e-06 26.6 0.0 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFR05633.1 - 0.0016 18.2 2.5 0.0023 17.7 0.2 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HECT PF00632.25 KFR05634.1 - 1.1e-93 314.1 0.2 2.3e-93 313.0 0.2 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 KFR05634.1 - 5.3e-18 65.0 3.5 1.4e-17 63.6 3.5 1.8 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A LPD11 PF18824.1 KFR05634.1 - 0.026 14.6 0.0 9.3 6.4 0.0 2.9 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 11 CLZ PF16526.5 KFR05635.1 - 3.5e-30 104.2 5.9 3.5e-30 104.2 5.9 2.7 2 0 0 2 2 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ion_trans PF00520.31 KFR05635.1 - 9e-30 103.7 8.8 1.3e-29 103.2 8.8 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KFR05635.1 - 7.4e-19 67.6 0.0 1.3e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Adaptin_binding PF10199.9 KFR05635.1 - 0.00013 22.5 1.0 0.0031 18.1 0.1 2.4 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 AAA_23 PF13476.6 KFR05635.1 - 0.00059 20.4 14.0 0.0058 17.2 7.0 2.5 2 0 0 2 2 2 1 AAA domain Peptidase_S49_N PF08496.10 KFR05635.1 - 0.00072 19.7 10.0 0.00072 19.7 10.0 2.9 3 0 0 3 3 3 1 Peptidase family S49 N-terminal Connexin PF00029.19 KFR05635.1 - 0.0021 17.9 2.2 0.0047 16.7 2.2 1.5 1 0 0 1 1 1 1 Connexin CPSF100_C PF13299.6 KFR05635.1 - 0.0026 18.0 2.5 0.0026 18.0 2.5 1.9 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 KFR05635.1 - 0.0073 16.2 7.2 0.0073 16.2 7.2 1.9 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 Ion_trans_2 PF07885.16 KFR05635.1 - 0.015 15.2 3.1 0.051 13.5 3.1 2.0 1 0 0 1 1 1 0 Ion channel Presenilin PF01080.17 KFR05635.1 - 0.017 13.9 0.3 0.026 13.3 0.3 1.3 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 KFR05635.1 - 0.019 15.1 0.1 0.037 14.2 0.0 1.6 2 0 0 2 2 1 0 DDHD domain Coilin_N PF15862.5 KFR05635.1 - 0.038 13.8 14.6 0.11 12.4 14.6 1.8 1 0 0 1 1 1 0 Coilin N-terminus DUF948 PF06103.11 KFR05635.1 - 0.061 13.6 0.6 5.2 7.4 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TFB6 PF17110.5 KFR05635.1 - 0.074 12.8 1.6 0.19 11.4 1.6 1.8 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF913 PF06025.12 KFR05635.1 - 0.083 11.9 0.6 0.16 10.9 0.6 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 KFR05635.1 - 0.093 11.5 5.5 0.15 10.8 5.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RNA_pol_Rpc4 PF05132.14 KFR05635.1 - 0.14 12.6 8.8 0.34 11.3 8.8 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 SpoIIP PF07454.11 KFR05635.1 - 0.16 11.4 11.1 0.35 10.3 11.1 1.5 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Tim54 PF11711.8 KFR05635.1 - 0.23 10.2 10.6 0.42 9.3 10.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FAM76 PF16046.5 KFR05635.1 - 0.23 10.8 18.6 0.11 11.8 0.4 2.3 2 0 0 2 2 2 0 FAM76 protein TMEM214 PF10151.9 KFR05635.1 - 0.38 9.1 13.7 0.69 8.3 13.7 1.3 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DUF1980 PF09323.10 KFR05635.1 - 1.8 8.5 5.4 8.1 6.3 5.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Zip PF02535.22 KFR05635.1 - 2.1 7.5 4.2 3.6 6.7 4.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Thg1C PF14413.6 KFR05635.1 - 2.8 8.1 12.2 9.9 6.3 12.2 1.9 1 0 0 1 1 1 0 Thg1 C terminal domain PPL5 PF18168.1 KFR05635.1 - 2.8 7.1 7.7 5.6 6.2 7.7 1.4 1 0 0 1 1 1 0 Prim-pol family 5 TRAP_alpha PF03896.16 KFR05635.1 - 4.2 6.5 9.8 8.2 5.5 9.8 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Afi1 PF07792.12 KFR05635.1 - 8.6 6.8 16.2 7.1 7.1 12.8 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking NARP1 PF12569.8 KFR05635.1 - 9.1 5.1 25.0 0.11 11.4 15.3 2.0 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 EMC3_TMCO1 PF01956.16 KFR05635.1 - 9.3 5.9 11.6 13 5.5 0.0 3.2 3 0 0 3 3 3 0 Integral membrane protein EMC3/TMCO1-like VWA_3 PF13768.6 KFR05636.1 - 0.00039 20.4 0.3 0.00059 19.8 0.3 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain TMEM131_like PF12371.8 KFR05637.1 - 3.2e-24 85.0 8.6 2.3e-23 82.2 0.8 4.5 4 0 0 4 4 4 1 Transmembrane protein 131-like ASH PF15780.5 KFR05637.1 - 2e-10 40.7 5.1 0.00094 19.3 0.2 7.0 7 0 0 7 7 7 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin fn3_5 PF06280.12 KFR05637.1 - 0.045 14.4 1.8 0.41 11.4 0.7 3.1 3 0 0 3 3 3 0 Fn3-like domain C2 PF00168.30 KFR05638.1 - 0.0022 18.2 0.0 0.0051 17.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain NHR2 PF08788.11 KFR05638.1 - 0.0065 16.2 0.5 0.21 11.4 0.2 2.7 2 0 0 2 2 2 1 NHR2 domain like UNC-50 PF05216.13 KFR05639.1 - 4.5e-91 304.3 22.9 5.2e-91 304.1 22.9 1.0 1 0 0 1 1 1 1 UNC-50 family Glyco_transf_54 PF04666.13 KFR05640.1 - 1.4e-135 450.8 1.5 2e-135 450.3 1.5 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF4750 PF15938.5 KFR05640.1 - 0.27 10.9 1.4 0.64 9.7 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4750) DUF4592 PF15262.6 KFR05642.1 - 1.2e-32 113.4 4.1 1.2e-32 113.4 4.1 3.1 2 2 0 2 2 2 1 Domain of unknown function (DUF4592) BPL_LplA_LipB PF03099.19 KFR05644.1 - 0.00044 20.1 0.0 0.00097 19.0 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family MIT_C PF16565.5 KFR05645.1 - 3.9e-56 189.0 0.0 6.5e-56 188.2 0.0 1.4 1 0 0 1 1 1 1 Phospholipase D-like domain at C-terminus of MIT MIT PF04212.18 KFR05645.1 - 0.00054 20.0 2.3 0.0012 18.8 2.3 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Ribosomal_L30 PF00327.20 KFR05646.1 - 1.1e-13 50.8 1.2 1.7e-13 50.2 1.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e SLT PF01464.20 KFR05647.1 - 8.8e-06 25.4 0.0 2.7e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 Transglycosylase SLT domain Agglutinin_C PF18021.1 KFR05647.1 - 0.061 13.8 0.1 0.53 10.8 0.0 2.1 1 1 0 2 2 2 0 Agglutinin C-terminal SLT PF01464.20 KFR05648.1 - 2.5e-06 27.1 0.0 5.4e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Transglycosylase SLT domain SLT_2 PF13406.6 KFR05648.1 - 0.014 14.7 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 Transglycosylase SLT domain Toxin_16 PF07945.11 KFR05648.1 - 0.053 13.4 0.8 0.12 12.3 0.8 1.5 1 0 0 1 1 1 0 Janus-atracotoxin SLT PF01464.20 KFR05649.1 - 0.042 13.5 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 Transglycosylase SLT domain Thioredoxin PF00085.20 KFR05650.1 - 3.2e-11 43.1 0.1 7.1e-11 42.0 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 KFR05650.1 - 5.3e-08 32.1 0.4 7.1e-08 31.7 0.4 1.1 1 0 0 1 1 1 1 Phosducin eIF-3_zeta PF05091.12 KFR05650.1 - 0.0056 15.7 1.0 0.0073 15.3 1.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3619 PF12279.8 KFR05650.1 - 0.083 13.2 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) MtaB PF12176.8 KFR05650.1 - 1.3 7.7 3.7 2.1 7.0 3.2 1.5 1 1 1 2 2 2 0 Methanol-cobalamin methyltransferase B subunit FapA PF03961.13 KFR05650.1 - 2.1 6.9 6.7 2.5 6.6 6.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A GTP_EFTU PF00009.27 KFR05651.1 - 5.3e-35 120.7 0.2 5.3e-35 120.7 0.2 2.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KFR05651.1 - 2e-19 69.6 2.9 3.6e-19 68.8 0.1 2.7 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 KFR05651.1 - 4.5e-14 52.1 0.4 1.3e-13 50.7 0.4 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 KFR05651.1 - 2.1e-11 44.0 8.8 1.2e-08 35.2 0.3 4.2 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFR05651.1 - 2.3e-06 27.7 0.1 2.3e-06 27.7 0.1 3.2 4 0 0 4 4 4 1 50S ribosome-binding GTPase Roc PF08477.13 KFR05651.1 - 0.0002 21.6 0.0 0.00068 19.8 0.0 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KFR05651.1 - 0.008 16.0 2.2 0.014 15.2 0.0 2.7 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein IMS PF00817.20 KFR05652.1 - 6.1e-43 146.4 0.0 1.1e-42 145.6 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KFR05652.1 - 2.2e-15 57.4 0.0 4.4e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain REV1_C PF16727.5 KFR05652.1 - 5.5e-14 52.3 0.7 1e-13 51.4 0.7 1.5 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain BRCT_2 PF16589.5 KFR05652.1 - 3.8e-10 40.0 0.0 9.4e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KFR05652.1 - 3.9e-08 33.6 0.0 9.2e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain UBM PF14377.6 KFR05652.1 - 3.2e-07 29.6 4.7 0.0075 15.7 0.2 2.6 2 0 0 2 2 2 2 Ubiquitin binding region LIG3_BRCT PF16759.5 KFR05652.1 - 7.5e-07 29.3 0.0 2.2e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain IMS_HHH PF11798.8 KFR05652.1 - 0.00013 22.1 0.0 0.015 15.6 0.0 2.8 2 0 0 2 2 2 1 IMS family HHH motif PTCB-BRCT PF12738.7 KFR05652.1 - 0.00037 20.4 0.0 0.0009 19.1 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain Cdd1 PF11731.8 KFR05652.1 - 0.019 15.2 0.0 0.055 13.7 0.0 1.8 1 0 0 1 1 1 0 Pathogenicity locus mCpol PF18182.1 KFR05652.1 - 0.021 15.1 0.0 0.062 13.6 0.0 1.8 1 0 0 1 1 1 0 minimal CRISPR polymerase domain DUF1805 PF08827.11 KFR05652.1 - 0.086 13.2 0.0 0.3 11.4 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) AF-4 PF05110.13 KFR05654.1 - 1.5e-69 235.4 16.0 3.4e-48 164.6 3.4 2.0 1 1 1 2 2 2 2 AF-4 proto-oncoprotein LON_substr_bdg PF02190.16 KFR05655.1 - 8.8e-23 81.3 0.0 1.5e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KFR05655.1 - 9.1e-11 41.4 15.8 2.3e-10 40.1 15.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFR05655.1 - 7.9e-10 38.4 9.5 1.5e-09 37.6 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFR05655.1 - 2.4e-07 30.7 8.3 2.4e-07 30.7 8.3 2.8 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFR05655.1 - 3e-07 30.2 14.7 7.4e-07 28.9 14.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFR05655.1 - 9.1e-07 29.1 14.8 9.1e-07 29.1 14.8 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KFR05655.1 - 5.6e-06 26.4 13.3 1.3e-05 25.2 13.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFR05655.1 - 7.7e-06 25.7 11.7 1.6e-05 24.7 11.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFR05655.1 - 8.5e-06 25.6 13.4 1.8e-05 24.6 13.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain U-box PF04564.15 KFR05655.1 - 0.00085 19.5 0.0 0.0019 18.3 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-rbx1 PF12678.7 KFR05655.1 - 0.0014 18.8 10.4 0.0036 17.5 10.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KFR05655.1 - 0.0022 18.1 8.0 0.0046 17.1 8.0 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KFR05655.1 - 0.04 13.8 6.4 0.084 12.8 6.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KFR05655.1 - 0.043 13.6 9.2 0.11 12.3 9.2 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Sulfotransfer_2 PF03567.14 KFR05656.1 - 1.1e-51 176.2 0.1 1.4e-51 175.8 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family SLC3A2_N PF16028.5 KFR05656.1 - 0.027 14.0 0.6 6.3 6.4 0.0 2.5 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus DUF1075 PF06388.11 KFR05656.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1075) Histone_H2A_C PF16211.5 KFR05659.1 - 1.1e-16 60.2 0.3 2.2e-16 59.3 0.3 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFR05659.1 - 4.6e-13 49.7 0.0 5.2e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFR05659.1 - 0.0018 18.5 0.0 0.0026 18.0 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone_H2A_C PF16211.5 KFR05660.1 - 7.9e-17 60.7 0.0 7.9e-17 60.7 0.0 2.0 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.24 KFR05660.1 - 1.5e-13 51.2 0.0 1.9e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFR05660.1 - 0.0028 17.9 0.0 0.0045 17.2 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Phosducin PF02114.16 KFR05661.1 - 7.8e-18 64.4 1.2 1.3e-17 63.7 0.9 1.3 1 1 0 1 1 1 1 Phosducin UPF0175 PF03683.13 KFR05661.1 - 0.0024 17.6 3.7 0.0031 17.2 0.9 2.6 3 1 2 5 5 5 1 Uncharacterised protein family (UPF0175) DUF3886 PF13025.6 KFR05661.1 - 0.02 15.1 5.8 0.02 15.1 5.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3886) Aim21 PF11489.8 KFR05661.1 - 0.37 9.6 3.7 0.5 9.2 3.7 1.1 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 21 GOLD_2 PF13897.6 KFR05661.1 - 0.52 10.8 2.2 0.48 10.9 0.9 1.6 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Ribosomal_L31e PF01198.19 KFR05662.1 - 2.5e-53 178.2 1.0 3.3e-53 177.9 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e Vsr PF03852.15 KFR05662.1 - 0.0067 16.3 0.1 0.014 15.2 0.0 1.6 1 1 1 2 2 2 1 DNA mismatch endonuclease Vsr CNOT11 PF10155.9 KFR05663.1 - 3.3e-55 185.6 6.3 5e-55 185.0 6.3 1.3 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 zf-RING_2 PF13639.6 KFR05664.1 - 6.1e-13 48.9 8.1 9.6e-13 48.3 8.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFR05664.1 - 1.7e-10 40.5 3.1 3.3e-10 39.5 3.1 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFR05664.1 - 9.3e-10 38.2 7.7 1.5e-09 37.5 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFR05664.1 - 9.5e-08 31.8 7.3 1.6e-07 31.1 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFR05664.1 - 2.9e-07 30.3 5.0 4.5e-07 29.7 5.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFR05664.1 - 4.6e-07 30.0 8.6 4.6e-07 30.0 8.6 1.8 2 1 0 2 2 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFR05664.1 - 6.7e-07 29.1 5.0 1.1e-06 28.3 5.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFR05664.1 - 5.5e-06 26.3 5.0 9.6e-06 25.5 5.0 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFR05664.1 - 7.7e-05 22.5 4.8 0.00012 21.9 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CrgA PF06781.12 KFR05664.1 - 0.0013 18.8 0.7 0.0024 17.9 0.7 1.4 1 0 0 1 1 1 1 Cell division protein CrgA PspB PF06667.12 KFR05664.1 - 0.0054 16.8 1.3 0.0086 16.1 0.2 1.9 2 0 0 2 2 2 1 Phage shock protein B zf-C3H2C3 PF17122.5 KFR05664.1 - 0.011 15.7 4.4 0.029 14.4 4.4 1.8 1 1 0 1 1 1 0 Zinc-finger zf-ANAPC11 PF12861.7 KFR05664.1 - 0.019 15.0 4.6 0.041 13.9 4.6 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFR05664.1 - 0.026 14.1 5.8 0.12 12.1 6.1 1.8 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type CDC24_OB3 PF17244.2 KFR05664.1 - 0.043 13.5 0.2 0.052 13.2 0.2 1.1 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 RINGv PF12906.7 KFR05664.1 - 0.48 10.6 3.7 1.1 9.5 3.7 1.6 1 1 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 KFR05664.1 - 1 9.6 3.8 3.8 7.8 3.8 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KFR05664.1 - 1.8 8.8 5.6 16 5.8 6.1 2.3 1 1 1 2 2 2 0 FANCL C-terminal domain PHD PF00628.29 KFR05664.1 - 2 8.3 6.2 1.6 8.7 4.7 1.7 2 0 0 2 2 1 0 PHD-finger Pyrid_oxidase_2 PF13883.6 KFR05665.1 - 1.1e-46 158.8 0.0 1.3e-46 158.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 KFR05665.1 - 0.0011 19.1 0.0 0.0015 18.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FBD PF08387.10 KFR05666.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 FBD RFX_DNA_binding PF02257.15 KFR05667.1 - 8e-18 64.8 0.1 8e-18 64.8 0.1 2.1 2 0 0 2 2 2 1 RFX DNA-binding domain CNH PF00780.22 KFR05668.1 - 3.4e-60 204.0 0.0 5.9e-60 203.2 0.0 1.4 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.25 KFR05668.1 - 3.7e-55 187.1 0.6 7.5e-55 186.1 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR05668.1 - 1.2e-40 139.5 0.0 2.5e-40 138.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ig_6 PF18452.1 KFR05669.1 - 5.9e-16 57.8 0.0 3.2e-13 49.0 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFR05669.1 - 1e-14 54.6 0.0 0.0001 22.6 0.0 3.4 3 1 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.6 KFR05669.1 - 5e-14 52.6 0.0 0.0018 18.8 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFR05669.1 - 3.3e-10 40.0 0.0 0.017 15.3 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFR05669.1 - 1.6e-09 37.7 0.0 0.014 15.4 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin I-set domain V-set PF07686.17 KFR05669.1 - 6.2e-09 36.0 0.1 0.018 15.2 0.0 4.3 4 1 0 4 4 4 3 Immunoglobulin V-set domain Izumo-Ig PF16706.5 KFR05669.1 - 0.005 16.9 0.0 0.25 11.4 0.0 2.4 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFR05669.1 - 0.073 13.5 2.1 3.3 8.2 0.0 4.0 3 3 0 3 3 3 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain TIR PF01582.20 KFR05670.1 - 2.6e-37 128.3 0.1 3.8e-37 127.8 0.1 1.2 1 0 0 1 1 1 1 TIR domain Ig_3 PF13927.6 KFR05670.1 - 5.2e-17 62.2 0.0 0.00017 22.1 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFR05670.1 - 4.1e-15 55.6 0.0 7e-05 22.8 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KFR05670.1 - 1.8e-14 53.8 1.6 8e-07 29.3 0.1 2.9 3 1 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFR05670.1 - 8.6e-13 48.3 0.2 0.00035 20.7 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Ig_6 PF18452.1 KFR05670.1 - 1.2e-10 40.7 0.1 4.9e-07 29.2 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFR05670.1 - 8.2e-08 32.4 6.7 0.066 13.4 0.7 5.0 3 2 2 5 5 5 2 Immunoglobulin V-set domain Izumo-Ig PF16706.5 KFR05670.1 - 0.00047 20.2 0.0 0.24 11.5 0.0 2.6 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain TIR_2 PF13676.6 KFR05670.1 - 0.015 15.9 0.0 0.036 14.7 0.0 1.6 1 0 0 1 1 1 0 TIR domain Ig_5 PF16681.5 KFR05670.1 - 0.03 14.7 0.1 4.6 7.7 0.0 3.4 3 0 0 3 3 3 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Arm-DNA-bind_2 PF12167.8 KFR05670.1 - 0.091 12.7 0.5 2.7 8.0 0.0 2.7 3 0 0 3 3 3 0 Arm DNA-binding domain C2-set PF05790.15 KFR05670.1 - 0.13 12.5 0.0 21 5.4 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin C2-set domain TIR PF01582.20 KFR05671.1 - 5.8e-32 110.9 0.0 9.3e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 TIR domain Ig_3 PF13927.6 KFR05671.1 - 1.5e-22 80.0 0.5 4.3e-08 33.6 0.1 3.6 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFR05671.1 - 2e-18 66.3 0.2 5.2e-06 26.4 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KFR05671.1 - 5e-17 62.0 1.5 3.2e-07 30.6 0.1 3.6 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFR05671.1 - 1.8e-13 50.4 0.4 0.0024 18.0 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin domain Ig_6 PF18452.1 KFR05671.1 - 9.8e-11 41.1 0.3 1.5e-08 34.0 0.1 2.5 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFR05671.1 - 6.6e-09 35.9 6.4 0.018 15.2 1.4 5.1 4 1 1 5 5 5 3 Immunoglobulin V-set domain T6SS_VasE PF05936.12 KFR05671.1 - 0.01 14.6 0.0 3.2 6.3 0.0 2.5 3 0 0 3 3 3 0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE Lep_receptor_Ig PF06328.11 KFR05671.1 - 0.023 14.6 0.7 3.1 7.8 0.0 3.8 4 0 0 4 4 4 0 Ig-like C2-type domain Adeno_E3_CR1 PF02440.15 KFR05671.1 - 0.023 14.5 0.5 0.023 14.5 0.5 2.9 3 0 0 3 3 3 0 Adenovirus E3 region protein CR1 TIR_2 PF13676.6 KFR05671.1 - 0.12 12.9 0.0 0.3 11.7 0.0 1.6 1 0 0 1 1 1 0 TIR domain TIR PF01582.20 KFR05672.1 - 3.1e-32 111.8 0.1 4.6e-32 111.2 0.1 1.2 1 0 0 1 1 1 1 TIR domain Ig_3 PF13927.6 KFR05672.1 - 1.9e-17 63.6 2.8 1.2e-06 29.1 0.0 3.7 4 0 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.6 KFR05672.1 - 1.6e-15 57.2 2.0 9.8e-07 29.0 0.3 3.5 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFR05672.1 - 4.9e-15 55.5 8.9 8.4e-06 25.9 0.1 4.0 4 0 0 4 4 4 3 Immunoglobulin domain I-set PF07679.16 KFR05672.1 - 5.7e-13 48.7 1.5 4.8e-05 23.4 0.1 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_6 PF18452.1 KFR05672.1 - 2.1e-12 46.4 2.6 5.8e-12 45.0 0.1 2.7 3 0 0 3 3 3 1 Immunoglobulin domain V-set PF07686.17 KFR05672.1 - 4e-06 27.0 7.5 0.75 10.0 0.1 4.6 3 3 0 3 3 3 3 Immunoglobulin V-set domain TIR_2 PF13676.6 KFR05672.1 - 0.00027 21.5 0.0 0.00056 20.5 0.0 1.4 1 0 0 1 1 1 1 TIR domain V-set_CD47 PF08204.11 KFR05672.1 - 0.00028 20.9 1.5 0.19 11.7 0.1 3.3 3 0 0 3 3 3 1 CD47 immunoglobulin-like domain Herpes_UL52 PF03121.15 KFR05672.1 - 0.033 14.1 0.7 0.38 10.7 0.1 2.6 2 0 0 2 2 2 0 Herpesviridae UL52/UL70 DNA primase Ig_4 PF16680.5 KFR05672.1 - 0.069 13.4 4.3 17 5.7 0.2 3.8 3 1 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain TMEM156 PF15106.6 KFR05672.1 - 0.079 12.4 1.5 0.08 12.4 0.3 1.6 2 0 0 2 2 2 0 TMEM156 protein family BiPBP_C PF06832.12 KFR05672.1 - 0.15 12.1 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family TIR PF01582.20 KFR05673.1 - 7.6e-38 130.1 0.0 1.3e-37 129.3 0.0 1.4 1 0 0 1 1 1 1 TIR domain Ig_6 PF18452.1 KFR05673.1 - 7.9e-26 89.4 0.5 3.5e-21 74.5 0.1 2.7 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 KFR05673.1 - 1.8e-16 60.5 1.1 3.5e-06 27.5 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFR05673.1 - 5.6e-13 48.9 1.2 6.6e-05 23.0 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KFR05673.1 - 3.2e-10 40.2 0.8 0.0005 20.4 0.3 3.4 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFR05673.1 - 3.2e-10 39.9 1.6 0.0062 16.6 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin I-set domain TIR_2 PF13676.6 KFR05673.1 - 5.6e-10 39.9 0.0 1.4e-09 38.6 0.0 1.7 1 0 0 1 1 1 1 TIR domain C1-set PF07654.15 KFR05673.1 - 0.0045 17.3 0.2 0.62 10.5 0.0 3.0 3 0 0 3 3 3 1 Immunoglobulin C1-set domain V-set PF07686.17 KFR05673.1 - 0.052 13.7 7.4 13 6.0 0.0 4.3 3 2 1 4 4 4 0 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFR05673.1 - 0.056 13.5 0.0 5.1 7.2 0.0 2.7 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFR05673.1 - 0.41 11.0 7.7 0.23 11.8 0.3 3.9 3 2 1 4 4 4 0 T-cell surface glycoprotein CD3 delta chain Na_H_Exchanger PF00999.21 KFR05674.1 - 1.6e-84 283.9 35.9 1.9e-84 283.7 35.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NEXCaM_BD PF16644.5 KFR05674.1 - 6.5e-36 123.1 0.8 6.5e-36 123.1 0.8 1.7 2 0 0 2 2 2 1 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin Tim17 PF02466.19 KFR05674.1 - 0.047 14.1 2.2 0.069 13.5 0.9 2.1 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family NiFe_hyd_3_EhaA PF17367.2 KFR05674.1 - 2.2 8.4 7.3 3.8 7.7 0.6 3.1 3 0 0 3 3 3 0 NiFe-hydrogenase-type-3 Eha complex subunit A Na_H_Exchanger PF00999.21 KFR05675.1 - 4e-90 302.4 40.8 4.5e-90 302.2 40.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MFS_1 PF07690.16 KFR05676.1 - 2e-39 135.5 22.5 2.7e-39 135.1 22.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFR05676.1 - 1e-08 34.5 4.5 1e-08 34.5 4.5 2.6 1 1 2 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KFR05676.1 - 2.1e-05 23.0 8.9 4.7e-05 21.9 0.3 3.2 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 KFR05676.1 - 3e-05 23.1 12.8 0.00022 20.2 12.8 1.9 1 1 0 1 1 1 1 MFS_1 like family MFS_4 PF06779.14 KFR05676.1 - 0.00039 19.8 4.4 0.00039 19.8 4.4 2.5 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB Claudin_2 PF13903.6 KFR05677.1 - 1.1e-52 178.7 6.6 1.2e-52 178.5 6.6 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFR05677.1 - 7.5e-06 25.9 8.1 0.0071 16.2 5.0 2.2 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family DUF4538 PF15061.6 KFR05677.1 - 0.21 11.4 9.7 2.1 8.2 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4538) L_HMGIC_fpl PF10242.9 KFR05677.1 - 0.75 10.0 8.7 2.6 8.2 8.7 2.0 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein Yae1_N PF09811.9 KFR05678.1 - 2.9e-12 46.1 40.5 1.8e+04 -6.2 40.5 4.2 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Ribosomal_S9 PF00380.19 KFR05682.1 - 1.8e-35 122.1 0.1 3.6e-35 121.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Vps39_2 PF10367.9 KFR05683.1 - 3.6e-30 104.6 0.1 9.6e-30 103.3 0.1 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KFR05683.1 - 6.9e-27 93.9 1.6 6.9e-27 93.9 1.6 3.2 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 KFR05683.1 - 2.7e-13 50.0 15.4 9.7e-08 32.0 6.8 2.5 2 0 0 2 2 2 2 Region in Clathrin and VPS CNH PF00780.22 KFR05683.1 - 1.6e-12 47.6 0.2 4.6e-12 46.1 0.1 1.8 2 0 0 2 2 2 1 CNH domain TPR_1 PF00515.28 KFR05683.1 - 8.8 6.3 6.5 50 4.0 0.4 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFR05683.1 - 9.6 6.6 7.9 5.3 7.4 0.4 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Ashwin PF15323.6 KFR05684.1 - 1.9e-75 253.8 9.8 2.1e-75 253.6 9.8 1.0 1 0 0 1 1 1 1 Developmental protein LIM PF00412.22 KFR05685.1 - 1.2e-47 159.9 69.6 7e-13 48.6 7.4 5.1 5 0 0 5 5 5 5 LIM domain Sgf11 PF08209.11 KFR05685.1 - 0.16 11.6 0.3 0.16 11.6 0.3 9.0 10 0 0 10 10 10 0 Sgf11 (transcriptional regulation protein) SH3_1 PF00018.28 KFR05686.1 - 6.8e-42 140.9 10.6 7.1e-14 51.1 0.1 4.7 5 0 0 5 5 5 3 SH3 domain SH3_9 PF14604.6 KFR05686.1 - 2.4e-39 133.0 3.8 1.7e-14 53.4 0.1 3.8 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.17 KFR05686.1 - 7.4e-28 96.0 6.7 1.8e-09 37.2 0.2 4.4 4 1 1 5 5 5 3 Variant SH3 domain SH2 PF00017.24 KFR05686.1 - 3.4e-22 78.3 0.0 6.7e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SH3_3 PF08239.11 KFR05686.1 - 5.7e-09 36.1 10.8 0.0029 17.9 0.5 3.7 4 0 0 4 4 4 3 Bacterial SH3 domain SH3_10 PF17902.1 KFR05686.1 - 5.1e-07 29.7 3.2 0.0014 18.7 0.3 3.0 3 0 0 3 3 3 2 SH3 domain hSH3 PF14603.6 KFR05686.1 - 3.1e-05 24.3 0.0 0.01 16.2 0.0 2.6 2 0 0 2 2 2 1 Helically-extended SH3 domain SH2_2 PF14633.6 KFR05686.1 - 0.0051 16.2 0.1 0.025 14.0 0.1 1.9 1 1 0 1 1 1 1 SH2 domain DUF5350 PF17299.2 KFR05686.1 - 0.13 12.8 2.8 1.6 9.2 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5350) SH3_4 PF06347.13 KFR05686.1 - 0.84 9.5 4.1 16 5.5 0.8 2.8 2 0 0 2 2 2 0 Bacterial SH3 domain Augurin PF15187.6 KFR05687.1 - 2.4e-51 172.7 2.1 2.6e-51 172.6 2.1 1.0 1 0 0 1 1 1 1 Oesophageal cancer-related gene 4 GDP_Man_Dehyd PF16363.5 KFR05688.1 - 7.9e-56 189.8 0.0 3.3e-55 187.8 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFR05688.1 - 2.3e-50 171.3 0.0 4e-50 170.5 0.0 1.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family UXS1_N PF11803.8 KFR05688.1 - 1.2e-24 86.4 0.0 2.6e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 UDP-glucuronate decarboxylase N-terminal NAD_binding_4 PF07993.12 KFR05688.1 - 2.2e-10 40.2 0.5 3e-06 26.6 0.0 2.7 2 1 0 3 3 3 2 Male sterility protein RmlD_sub_bind PF04321.17 KFR05688.1 - 5.9e-10 38.7 0.0 8.4e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KFR05688.1 - 4.6e-09 35.7 0.0 4e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KFR05688.1 - 2.2e-08 33.6 0.2 0.0002 20.6 0.1 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein 7tm_1 PF00001.21 KFR05689.1 - 1.4e-25 90.1 10.3 1.6e-25 90.0 10.3 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFR05689.1 - 2.2e-05 23.9 5.5 3e-05 23.5 5.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv TAS2R PF05296.13 KFR05689.1 - 6.9e-05 22.1 0.7 8.1e-05 21.9 0.7 1.1 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) DUF2975 PF11188.8 KFR05689.1 - 0.0035 17.2 3.1 0.0047 16.8 3.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2975) BCD PF15461.6 KFR05689.1 - 0.0041 16.6 2.3 0.0041 16.6 2.3 1.4 1 1 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase UbiA PF01040.18 KFR05689.1 - 0.007 15.7 6.5 0.01 15.1 6.5 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family HemY_N PF07219.13 KFR05689.1 - 0.76 10.0 3.9 1.7 8.9 0.1 2.3 1 1 1 2 2 2 0 HemY protein N-terminus DUF1201 PF06716.11 KFR05689.1 - 6.4 6.9 12.2 0.41 10.7 6.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1201) Glyco_transf_29 PF00777.18 KFR05690.1 - 2.6e-37 128.7 0.0 5.7e-37 127.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) SSF PF00474.17 KFR05691.1 - 2.5e-33 115.6 27.8 3.6e-33 115.0 27.8 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Sulfotransfer_1 PF00685.27 KFR05692.1 - 2.9e-94 315.5 2.8 3.9e-94 315.1 2.8 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFR05692.1 - 1.6e-06 28.6 0.2 7.4e-06 26.5 0.1 1.9 2 0 0 2 2 2 1 Sulfotransferase family Rab_bind PF16704.5 KFR05693.1 - 7.6e-38 128.4 8.4 7.6e-38 128.4 8.4 9.0 9 2 1 10 10 10 2 Rab binding domain GRIP PF01465.20 KFR05693.1 - 4.3e-17 61.7 0.7 1.4e-16 60.1 0.3 2.3 2 0 0 2 2 2 1 GRIP domain SHE3 PF17078.5 KFR05693.1 - 0.0064 16.2 22.0 0.0064 16.2 22.0 12.2 2 1 7 11 11 11 3 SWI5-dependent HO expression protein 3 LIM PF00412.22 KFR05694.1 - 6.2e-63 208.9 62.4 1.7e-14 53.8 3.0 5.1 5 0 0 5 5 5 5 LIM domain zf-RRN7 PF11781.8 KFR05694.1 - 0.29 10.9 0.1 0.29 10.9 0.1 9.1 10 1 0 10 10 10 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TPR_2 PF07719.17 KFR05696.1 - 8.1e-10 38.1 0.6 1.1e-05 25.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFR05696.1 - 7.4e-08 31.9 0.6 3.9e-05 23.3 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFR05696.1 - 4.6e-07 30.1 0.0 0.0029 18.3 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFR05696.1 - 0.0027 17.8 1.0 0.009 16.2 0.0 2.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFR05696.1 - 0.012 16.3 0.1 20 5.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFR05696.1 - 0.015 15.3 0.1 0.32 11.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFR05696.1 - 0.023 14.4 0.2 0.17 11.6 0.1 2.4 2 1 1 3 3 3 0 TPR repeat TPR_19 PF14559.6 KFR05696.1 - 0.025 15.1 0.6 14 6.3 0.2 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFR05696.1 - 0.03 14.2 0.3 4.2 7.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFR05696.1 - 0.042 14.2 0.4 16 6.2 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFR05696.1 - 0.068 13.3 0.0 1.1 9.5 0.0 2.5 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFR05696.1 - 0.11 12.8 0.2 1.3 9.4 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.12 KFR05696.1 - 0.11 13.2 0.9 14 6.5 0.2 2.7 2 1 0 2 2 2 0 Sel1 repeat Ran_BP1 PF00638.18 KFR05697.1 - 4.1e-57 191.7 0.5 4.7e-57 191.5 0.5 1.0 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 KFR05697.1 - 0.00011 22.1 0.1 0.00019 21.3 0.1 1.4 1 1 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 KFR05697.1 - 0.0084 16.4 0.1 0.01 16.1 0.1 1.1 1 0 0 1 1 1 1 VID27 PH-like domain Pro_isomerase PF00160.21 KFR05698.1 - 9.6e-42 142.9 0.6 1e-41 142.8 0.6 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Spc42p PF11544.8 KFR05699.1 - 0.002 18.1 6.3 0.002 18.1 6.3 2.4 2 1 0 2 2 2 1 Spindle pole body component Spc42p Atg14 PF10186.9 KFR05699.1 - 0.0048 16.0 16.1 0.0067 15.6 16.1 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 bZIP_1 PF00170.21 KFR05699.1 - 0.014 15.5 3.4 0.014 15.5 3.4 3.5 2 1 0 3 3 3 0 bZIP transcription factor RACo_linker PF17650.1 KFR05699.1 - 0.034 14.0 2.2 0.14 12.0 0.3 2.3 1 1 1 2 2 2 0 RACo linker region NPV_P10 PF05531.12 KFR05699.1 - 0.039 14.4 2.2 0.039 14.4 2.2 2.9 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein RVT_connect PF06815.13 KFR05699.1 - 0.12 12.7 3.2 0.34 11.2 0.1 2.6 1 1 0 2 2 2 0 Reverse transcriptase connection domain DUF87 PF01935.17 KFR05699.1 - 0.17 11.9 7.6 0.15 12.1 5.9 1.7 1 1 0 1 1 1 0 Helicase HerA, central domain FapA PF03961.13 KFR05699.1 - 0.17 10.4 12.3 0.23 10.0 12.3 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Lipase_chap PF03280.14 KFR05699.1 - 0.31 11.0 13.6 0.49 10.3 13.6 1.2 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein HWE_HK PF07536.14 KFR05699.1 - 0.32 11.7 5.6 11 6.9 1.6 2.7 2 1 0 2 2 2 0 HWE histidine kinase FUSC PF04632.12 KFR05699.1 - 0.36 9.3 3.5 0.48 8.9 3.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Rootletin PF15035.6 KFR05699.1 - 0.37 10.8 21.7 0.26 11.3 20.2 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF3854 PF12965.7 KFR05699.1 - 0.42 10.6 3.8 0.24 11.4 1.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3854) DASH_Dad1 PF08649.10 KFR05699.1 - 0.5 10.6 4.3 0.27 11.5 0.8 2.4 2 1 1 3 3 2 0 DASH complex subunit Dad1 Baculo_PEP_C PF04513.12 KFR05699.1 - 0.63 10.1 5.0 0.69 10.0 2.8 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Matrilin_ccoil PF10393.9 KFR05699.1 - 1.2 9.0 6.8 8.1 6.4 0.2 3.4 3 1 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Phage_GPO PF05929.11 KFR05699.1 - 1.3 8.6 10.3 1.2 8.7 9.3 1.4 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase CorA PF01544.18 KFR05699.1 - 2 7.6 13.0 2 7.6 11.2 1.8 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DHR10 PF18595.1 KFR05699.1 - 3 7.9 24.8 0.04 14.0 13.9 2.4 1 1 0 2 2 2 0 Designed helical repeat protein 10 domain HALZ PF02183.18 KFR05699.1 - 3.1 8.1 12.6 0.27 11.5 3.4 3.8 3 1 1 4 4 4 0 Homeobox associated leucine zipper DUF390 PF04094.14 KFR05699.1 - 4.7 5.4 8.9 0.7 8.1 3.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF390) DUF1664 PF07889.12 KFR05699.1 - 5.3 7.1 11.2 0.92 9.6 5.8 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) ATG11 PF10377.9 KFR05699.1 - 6.9 6.7 12.1 8.8 6.4 1.3 3.0 2 2 0 2 2 2 0 Autophagy-related protein 11 DUF5595 PF18077.1 KFR05699.1 - 7.2 6.8 10.1 15 5.8 1.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5595) NiFe-hyd_HybE PF11939.8 KFR05700.1 - 0.083 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 [NiFe]-hydrogenase assembly, chaperone, HybE SID-1_RNA_chan PF13965.6 KFR05701.1 - 0.033 12.6 0.3 0.044 12.2 0.3 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CLN3 PF02487.17 KFR05701.1 - 0.084 11.9 0.5 0.12 11.4 0.5 1.1 1 0 0 1 1 1 0 CLN3 protein KI67R PF08065.12 KFR05701.1 - 1.1 9.9 5.3 0.69 10.5 2.5 2.0 2 0 0 2 2 2 0 KI67R (NUC007) repeat OAD_gamma PF04277.13 KFR05701.1 - 1.1 9.8 9.7 17 6.1 9.7 2.2 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain TNFR_c6 PF00020.18 KFR05701.1 - 1.8 9.0 23.4 0.056 13.9 8.2 3.7 1 1 3 4 4 4 0 TNFR/NGFR cysteine-rich region Septin PF00735.18 KFR05702.1 - 7.7e-96 320.7 0.9 7.7e-96 320.7 0.9 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KFR05702.1 - 3.6e-05 23.8 0.0 9e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFR05702.1 - 0.00022 21.6 0.1 0.00066 20.1 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.27 KFR05702.1 - 0.00047 19.8 1.8 0.61 9.6 0.0 3.1 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KFR05702.1 - 0.001 19.4 0.2 0.0063 16.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KFR05702.1 - 0.003 17.1 0.0 0.0075 15.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region Roc PF08477.13 KFR05702.1 - 0.0036 17.5 0.1 0.017 15.3 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KFR05702.1 - 0.0036 17.2 3.5 0.052 13.5 0.0 3.0 3 1 0 3 3 3 1 RsgA GTPase AAA_29 PF13555.6 KFR05702.1 - 0.0043 16.8 0.1 0.0092 15.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KFR05702.1 - 0.0072 16.8 0.4 0.025 15.1 0.0 2.1 2 0 0 2 2 2 1 ABC transporter RHD3 PF05879.12 KFR05702.1 - 0.0098 14.1 0.4 0.0098 14.1 0.4 2.6 3 0 0 3 3 3 1 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.23 KFR05702.1 - 0.01 15.9 0.1 0.01 15.9 0.1 2.3 2 0 0 2 2 2 0 Dynamin family G-alpha PF00503.20 KFR05702.1 - 0.013 14.6 8.2 0.028 13.6 0.1 3.1 2 1 0 3 3 3 0 G-protein alpha subunit AIG1 PF04548.16 KFR05702.1 - 0.014 14.7 5.1 0.017 14.5 0.0 2.4 2 0 0 2 2 2 0 AIG1 family T2SSE PF00437.20 KFR05702.1 - 0.023 13.8 0.1 0.058 12.4 0.1 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein Microtub_bd PF16796.5 KFR05702.1 - 0.036 14.0 2.3 0.057 13.4 0.0 2.4 3 0 0 3 3 3 0 Microtubule binding FtsK_SpoIIIE PF01580.18 KFR05702.1 - 0.039 13.3 0.1 0.097 12.0 0.1 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Viral_helicase1 PF01443.18 KFR05702.1 - 0.061 13.0 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase IIGP PF05049.13 KFR05702.1 - 0.08 12.0 7.5 0.16 11.0 0.1 2.8 2 1 0 3 3 3 0 Interferon-inducible GTPase (IIGP) DUF87 PF01935.17 KFR05702.1 - 0.54 10.3 0.1 0.54 10.3 0.1 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain zf-H2C2_2 PF13465.6 KFR05703.1 - 0.0024 18.2 0.8 0.0024 18.2 0.8 5.3 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR05703.1 - 0.011 16.5 0.1 0.011 16.5 0.1 5.9 5 0 0 5 5 5 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFR05703.1 - 0.09 12.6 0.0 0.09 12.6 0.0 4.8 6 0 0 6 6 6 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFR05703.1 - 0.13 12.7 0.1 0.13 12.7 0.1 5.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type DUF4462 PF14692.6 KFR05704.1 - 0.13 11.8 0.1 0.27 10.7 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) Smg4_UPF3 PF03467.15 KFR05705.1 - 2.8e-49 167.5 0.1 2.8e-49 167.5 0.1 3.3 2 1 0 2 2 2 1 Smg-4/UPF3 family ANAPC3 PF12895.7 KFR05706.1 - 1.8e-28 98.6 16.4 1.1e-20 73.6 10.1 5.6 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KFR05706.1 - 1.2e-23 81.2 17.9 0.00015 21.6 0.1 10.2 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.28 KFR05706.1 - 1.5e-22 78.4 16.8 4.9e-08 32.5 0.2 8.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFR05706.1 - 8.1e-18 64.5 11.9 4.5e-10 39.7 0.1 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFR05706.1 - 1.5e-16 59.2 7.3 0.0017 18.4 0.0 7.2 8 0 0 8 8 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFR05706.1 - 2.6e-13 49.0 5.9 1.5e-05 24.7 0.1 4.9 5 1 1 6 6 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFR05706.1 - 6.4e-12 44.9 1.8 0.00047 19.9 0.3 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFR05706.1 - 4.4e-09 35.9 1.7 3.6e-06 26.6 0.0 4.7 5 1 0 5 5 4 1 TPR repeat TPR_17 PF13431.6 KFR05706.1 - 4.5e-09 36.1 0.1 1.2 9.7 0.0 6.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFR05706.1 - 5.9e-09 36.3 4.9 0.36 11.4 3.7 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFR05706.1 - 2.5e-08 34.4 7.7 0.13 13.0 0.0 5.0 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFR05706.1 - 5.9e-07 29.5 0.2 0.073 13.2 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFR05706.1 - 8.5e-06 26.2 11.5 3.8 8.6 0.0 7.4 5 3 3 8 8 7 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KFR05706.1 - 0.012 15.6 8.4 0.16 12.0 2.0 3.5 3 0 0 3 3 3 0 Putative TPR-like repeat TPR_3 PF07720.12 KFR05706.1 - 0.028 14.4 2.0 7.2 6.7 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFR05706.1 - 0.06 14.0 13.0 1.2 9.9 0.5 6.1 8 0 0 8 8 7 0 Tetratricopeptide repeat MIT PF04212.18 KFR05706.1 - 0.11 12.6 1.7 9 6.4 0.1 4.0 5 0 0 5 5 3 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 KFR05706.1 - 0.27 11.4 7.9 1.4 9.1 0.3 4.2 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF5113 PF17140.4 KFR05706.1 - 6.8 6.5 11.8 3 7.6 0.0 4.3 4 1 1 5 5 5 0 Domain of unknown function (DUF5113) C2 PF00168.30 KFR05707.1 - 6.6e-36 122.7 0.1 2.4e-17 63.1 0.0 3.3 2 1 0 2 2 2 2 C2 domain RasGAP PF00616.19 KFR05707.1 - 2.8e-29 102.3 0.1 5e-19 68.8 0.1 2.4 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase PH PF00169.29 KFR05707.1 - 6.4e-15 55.5 1.9 1.6e-14 54.2 0.4 2.4 2 0 0 2 2 2 1 PH domain BTK PF00779.19 KFR05707.1 - 1.1e-13 50.7 5.8 2e-13 49.9 5.8 1.5 1 0 0 1 1 1 1 BTK motif PH_9 PF15410.6 KFR05707.1 - 0.01 16.2 0.1 0.046 14.1 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain PH_8 PF15409.6 KFR05707.1 - 0.015 15.6 0.1 0.047 14.0 0.1 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain Laminin_G_1 PF00054.23 KFR05708.1 - 5.5e-30 104.3 0.0 3.7e-21 75.7 0.0 2.3 2 0 0 2 2 2 2 Laminin G domain Laminin_G_2 PF02210.24 KFR05708.1 - 1.3e-26 93.6 0.0 8.9e-14 52.2 0.0 2.2 2 0 0 2 2 2 2 Laminin G domain EGF_CA PF07645.15 KFR05708.1 - 1e-21 76.8 52.6 3e-08 33.7 6.8 5.0 4 0 0 4 4 4 4 Calcium-binding EGF domain Gla PF00594.20 KFR05708.1 - 4e-17 62.1 9.0 4e-17 62.1 9.0 1.8 2 0 0 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain cEGF PF12662.7 KFR05708.1 - 1.1e-16 60.4 33.1 3e-08 33.4 4.6 5.0 4 0 0 4 4 4 3 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFR05708.1 - 3.2e-13 49.7 59.1 5.1e-08 33.1 10.5 4.6 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site EGF PF00008.27 KFR05708.1 - 7.5e-10 38.9 45.3 3.2e-06 27.3 5.6 4.9 4 0 0 4 4 4 4 EGF-like domain EGF_3 PF12947.7 KFR05708.1 - 4.1e-05 23.7 46.6 0.0087 16.2 4.1 4.8 4 0 0 4 4 4 2 EGF domain hEGF PF12661.7 KFR05708.1 - 4.9e-05 23.8 32.8 0.055 14.1 1.2 5.4 4 0 0 4 4 4 3 Human growth factor-like EGF FAM70 PF14967.6 KFR05709.1 - 7.4e-164 545.0 4.9 8.2e-164 544.8 4.9 1.0 1 0 0 1 1 1 1 FAM70 protein DUF4064 PF13273.6 KFR05709.1 - 0.00019 21.6 11.0 0.0036 17.6 6.2 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF4064) Phage_holin_3_2 PF04550.12 KFR05709.1 - 0.061 13.9 4.8 0.32 11.6 0.5 2.3 2 0 0 2 2 2 0 Phage holin family 2 DUF2407_C PF13373.6 KFR05709.1 - 0.77 9.9 1.9 6.4 6.9 1.0 2.2 2 0 0 2 2 2 0 DUF2407 C-terminal domain Na_K-ATPase PF00287.18 KFR05710.1 - 9e-102 340.1 0.6 1e-101 339.9 0.6 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain DP PF08781.10 KFR05711.1 - 3.4e-64 214.9 2.1 3.4e-64 214.9 2.1 1.8 2 1 1 3 3 3 1 Transcription factor DP E2F_TDP PF02319.20 KFR05711.1 - 8e-27 93.1 0.1 1.8e-26 92.0 0.1 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain LMBR1 PF04791.16 KFR05711.1 - 0.21 10.4 1.9 0.22 10.4 1.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Na_H_Exchanger PF00999.21 KFR05712.1 - 5.4e-71 239.4 41.3 6.9e-71 239.0 41.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Glyco_hydro_36 PF17167.4 KFR05712.1 - 0.11 11.2 0.3 0.17 10.6 0.3 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain DUF16 PF01519.16 KFR05712.1 - 3.2 8.3 7.0 5.3 7.6 6.5 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 Peptidase_S46 PF10459.9 KFR05712.1 - 8.3 4.9 9.7 11 4.5 9.7 1.1 1 0 0 1 1 1 0 Peptidase S46 Cullin_binding PF03556.15 KFR05713.1 - 3.7e-38 130.7 0.6 3.7e-38 130.7 0.6 2.0 2 1 0 2 2 2 1 Cullin binding UBA_4 PF14555.6 KFR05713.1 - 3.3e-09 36.4 2.7 4.3e-09 36.1 0.0 2.6 3 0 0 3 3 3 1 UBA-like domain ADP_ribosyl_GH PF03747.14 KFR05714.1 - 1.1e-53 182.9 0.1 1.2e-53 182.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase RabGAP-TBC PF00566.18 KFR05716.1 - 7.9e-57 192.4 0.1 1.1e-56 191.9 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Lamp PF01299.17 KFR05717.1 - 7e-62 207.7 10.9 2.2e-48 163.9 2.0 2.2 2 0 0 2 2 2 2 Lysosome-associated membrane glycoprotein (Lamp) ATP-synt_S1 PF05827.12 KFR05717.1 - 9e-09 35.3 1.7 1.3e-06 28.3 0.0 2.3 2 0 0 2 2 2 2 Vacuolar ATP synthase subunit S1 (ATP6S1) PgdA_N PF18627.1 KFR05717.1 - 0.11 12.2 0.6 0.2 11.3 0.6 1.4 1 0 0 1 1 1 0 Peptidoglycan GlcNAc deacetylase N-terminal domain Cullin PF00888.22 KFR05718.1 - 6.8e-207 688.9 19.7 1e-206 688.3 19.7 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KFR05718.1 - 3e-24 84.8 0.3 1.3e-23 82.8 0.3 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain SecA_SW PF07516.13 KFR05718.1 - 0.015 15.4 0.4 0.015 15.4 0.4 3.1 2 1 1 3 3 3 0 SecA Wing and Scaffold domain PG_binding_4 PF12229.8 KFR05718.1 - 0.9 9.8 3.5 3.4 8.0 0.1 3.5 4 0 0 4 4 4 0 Putative peptidoglycan binding domain Trypsin PF00089.26 KFR05719.1 - 3.9e-22 79.1 0.0 6.8e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Trypsin Gla PF00594.20 KFR05719.1 - 2.1e-17 63.0 8.8 4.1e-17 62.1 8.8 1.5 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain FXa_inhibition PF14670.6 KFR05719.1 - 6.2e-11 42.4 27.7 4.4e-08 33.3 10.9 3.0 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site EGF PF00008.27 KFR05719.1 - 1.1e-08 35.2 28.6 3.8e-08 33.5 8.5 3.4 3 0 0 3 3 3 2 EGF-like domain cEGF PF12662.7 KFR05719.1 - 7.3e-07 29.0 10.6 0.00011 22.0 0.7 3.1 2 0 0 2 2 2 2 Complement Clr-like EGF-like hEGF PF12661.7 KFR05719.1 - 3.7e-05 24.2 5.0 3.7e-05 24.2 5.0 3.5 3 0 0 3 3 3 2 Human growth factor-like EGF DUF1986 PF09342.11 KFR05719.1 - 0.00019 21.8 0.0 0.00033 21.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) EGF_CA PF07645.15 KFR05719.1 - 0.0058 16.8 32.1 0.055 13.7 8.4 3.1 2 1 1 3 3 3 2 Calcium-binding EGF domain EGF_3 PF12947.7 KFR05719.1 - 0.1 12.8 19.3 0.09 13.0 5.9 3.2 2 1 0 2 2 2 0 EGF domain Plasmod_Pvs28 PF06247.11 KFR05719.1 - 0.46 10.8 16.1 4.1 7.8 4.5 2.9 2 0 0 2 2 2 0 Pvs28 EGF domain Trypsin PF00089.26 KFR05720.1 - 5.6e-65 219.3 0.1 6.2e-65 219.1 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFR05720.1 - 1.8e-05 25.6 0.0 3.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFR05720.1 - 0.00017 22.0 0.0 0.00028 21.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin PF00089.26 KFR05721.1 - 1.3e-65 221.3 0.2 2e-65 220.7 0.2 1.3 1 0 0 1 1 1 1 Trypsin Gla PF00594.20 KFR05721.1 - 8.4e-19 67.5 9.8 1.9e-18 66.3 8.7 2.1 1 1 1 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain FXa_inhibition PF14670.6 KFR05721.1 - 5.5e-10 39.4 19.8 1.2e-09 38.3 5.4 2.9 1 1 1 2 2 2 2 Coagulation Factor Xa inhibitory site EGF PF00008.27 KFR05721.1 - 2.3e-07 31.0 8.0 2.3e-07 31.0 8.0 3.1 3 0 0 3 3 3 1 EGF-like domain DUF1986 PF09342.11 KFR05721.1 - 7.5e-07 29.5 0.0 1.4e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) hEGF PF12661.7 KFR05721.1 - 0.00028 21.4 5.3 0.00028 21.4 5.3 3.2 2 0 0 2 2 2 1 Human growth factor-like EGF Trypsin_2 PF13365.6 KFR05721.1 - 0.096 13.6 0.1 0.17 12.8 0.1 1.5 1 1 0 1 1 1 0 Trypsin-like peptidase domain RhoGEF PF00621.20 KFR05722.1 - 4e-39 134.8 5.6 4e-39 134.8 5.6 3.6 3 1 0 3 3 3 1 RhoGEF domain PH PF00169.29 KFR05722.1 - 2.3e-09 37.7 0.1 5.7e-09 36.4 0.1 1.7 1 0 0 1 1 1 1 PH domain CRAL_TRIO_2 PF13716.6 KFR05722.1 - 2.4e-08 34.2 0.0 5.9e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Spectrin PF00435.21 KFR05722.1 - 1.2e-07 32.1 15.6 0.00015 22.2 0.0 4.9 3 2 1 4 4 4 2 Spectrin repeat PH_10 PF15411.6 KFR05722.1 - 0.0027 18.0 0.0 0.0082 16.4 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PhoLip_ATPase_C PF16212.5 KFR05723.1 - 5.5e-80 268.7 29.7 5.5e-80 268.7 29.7 2.1 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFR05723.1 - 6.6e-22 77.0 0.3 6.6e-22 77.0 0.3 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 KFR05723.1 - 3.8e-11 42.8 0.5 1.6e-10 40.8 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KFR05723.1 - 1.5e-10 41.1 0.1 2.6e-09 37.0 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFR05723.1 - 1.5e-10 41.7 0.6 5.3e-05 23.6 0.1 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFR05723.1 - 0.00063 19.5 0.0 0.083 12.6 0.0 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFR05723.1 - 0.0048 17.3 0.1 0.42 11.0 0.1 2.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Mab-21 PF03281.14 KFR05783.1 - 5.6e-10 39.0 3.8 3.9e-08 32.9 3.9 2.1 1 1 0 1 1 1 1 Mab-21 protein Ion_trans_2 PF07885.16 KFR05784.1 - 9.8e-32 108.8 18.1 2.8e-17 62.5 0.4 2.9 3 0 0 3 3 3 2 Ion channel DUF1104 PF06518.11 KFR05784.1 - 0.059 13.8 0.6 0.093 13.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) IclR PF01614.18 KFR05784.1 - 0.21 11.4 0.3 0.34 10.7 0.3 1.3 1 0 0 1 1 1 0 Bacterial transcriptional regulator Dapper PF15268.6 KFR05786.1 - 1.5e-226 755.1 29.5 2.1e-225 751.3 29.5 1.9 1 1 0 1 1 1 1 Dapper zf-Tim10_DDP PF02953.15 KFR05788.1 - 1.7e-17 62.8 3.9 2.2e-17 62.5 3.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2116 PF09889.9 KFR05788.1 - 0.021 14.8 1.0 0.031 14.3 1.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) RBB1NT PF08169.11 KFR05789.1 - 4.1e-37 126.2 2.7 4.5e-37 126.1 0.2 2.6 2 0 0 2 2 2 1 RBB1NT (NUC162) domain ARID PF01388.21 KFR05789.1 - 1.1e-20 74.1 0.1 2.3e-20 73.0 0.1 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Tudor-knot PF11717.8 KFR05789.1 - 1.8e-13 50.2 1.9 8.3e-13 48.0 2.0 2.1 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Tudor_2 PF18104.1 KFR05789.1 - 0.0092 15.6 0.0 0.037 13.7 0.0 2.1 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain PWWP PF00855.17 KFR05789.1 - 0.011 16.1 0.1 0.011 16.1 0.1 4.3 5 1 0 5 5 5 0 PWWP domain Tudor_3 PF18115.1 KFR05789.1 - 0.04 13.8 0.2 16 5.5 0.0 2.8 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain Proteasome PF00227.26 KFR05790.1 - 2.1e-50 170.9 0.2 2.5e-50 170.6 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFR05790.1 - 1.5e-14 53.3 0.1 2.6e-14 52.6 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Actin PF00022.19 KFR05791.1 - 2e-49 168.3 0.0 4.1e-47 160.7 0.0 2.5 1 1 0 1 1 1 1 Actin DUF4696 PF15767.5 KFR05792.1 - 5.2e-143 477.7 62.8 8e-143 477.1 62.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4696) DUF4611 PF15387.6 KFR05792.1 - 0.0021 18.3 8.4 0.009 16.2 8.4 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) Nop14 PF04147.12 KFR05792.1 - 0.0049 15.2 6.2 0.0069 14.7 6.2 1.2 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.10 KFR05792.1 - 0.008 15.6 1.8 0.015 14.6 1.8 1.6 1 0 0 1 1 1 1 BUD22 BSP_II PF05432.11 KFR05792.1 - 0.0082 15.9 9.3 0.0082 15.9 9.3 2.1 2 0 0 2 2 1 1 Bone sialoprotein II (BSP-II) Voldacs PF03517.13 KFR05792.1 - 0.012 15.8 4.8 0.03 14.4 4.8 1.7 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling SDA1 PF05285.12 KFR05792.1 - 0.013 15.0 5.4 0.025 14.0 5.4 1.5 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 KFR05792.1 - 0.021 12.9 11.5 0.033 12.3 11.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 KFR05792.1 - 0.037 13.3 2.5 0.075 12.2 2.5 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Plasmodium_Vir PF05795.11 KFR05792.1 - 0.047 13.1 0.1 0.12 11.8 0.1 1.8 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RNA_pol_3_Rpc31 PF11705.8 KFR05792.1 - 0.14 12.4 13.0 0.36 11.0 13.0 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FAM176 PF14851.6 KFR05792.1 - 0.15 11.8 6.8 2.3 7.9 7.6 2.2 2 0 0 2 2 2 0 FAM176 family VID27_N PF17748.1 KFR05792.1 - 0.2 11.5 4.2 0.34 10.7 4.2 1.3 1 0 0 1 1 1 0 VID27 N-terminal region NOA36 PF06524.12 KFR05792.1 - 0.7 9.2 9.1 1.1 8.6 9.1 1.2 1 0 0 1 1 1 0 NOA36 protein Paf1 PF03985.13 KFR05792.1 - 1.1 8.2 10.7 1.9 7.4 10.7 1.3 1 0 0 1 1 1 0 Paf1 Sigma70_ner PF04546.13 KFR05792.1 - 1.6 8.6 10.0 3.1 7.6 10.0 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region CAF1A PF12253.8 KFR05792.1 - 1.7 8.9 14.1 47 4.3 12.7 2.6 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A DUF4746 PF15928.5 KFR05792.1 - 1.8 7.9 8.7 4 6.8 8.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) HSP90 PF00183.18 KFR05792.1 - 2.3 7.0 7.2 3.7 6.3 7.2 1.2 1 0 0 1 1 1 0 Hsp90 protein PPP4R2 PF09184.11 KFR05792.1 - 3.5 7.1 12.0 6.4 6.3 12.0 1.5 1 0 0 1 1 1 0 PPP4R2 RRN3 PF05327.11 KFR05792.1 - 6.6 5.1 8.6 10 4.5 8.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Astro_capsid_p PF12226.8 KFR05792.1 - 9.1 5.3 12.6 16 4.5 12.6 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein SLC35F PF06027.12 KFR05793.1 - 1.3e-05 24.9 10.9 2e-05 24.3 10.9 1.3 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 KFR05793.1 - 3.7e-05 23.9 12.1 3.7e-05 23.9 12.1 3.2 2 2 0 2 2 2 1 EamA-like transporter family DUF1418 PF07214.12 KFR05793.1 - 0.8 9.6 2.9 1.4 8.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) DUF4619 PF15398.6 KFR05794.1 - 4.9e-95 318.5 2.7 5.5e-95 318.3 2.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4619) Acetyltransf_1 PF00583.25 KFR05795.1 - 1.1e-17 64.4 0.0 1.7e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFR05795.1 - 5.8e-12 45.7 0.0 9.2e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFR05795.1 - 7.1e-12 45.6 0.0 1.2e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFR05795.1 - 5.5e-09 35.9 0.0 1.1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KFR05795.1 - 6.8e-05 22.6 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KFR05795.1 - 0.00015 22.4 0.0 0.00023 21.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFR05795.1 - 0.0015 18.6 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TGS PF02824.21 KFR05795.1 - 0.17 12.0 0.0 0.42 10.7 0.0 1.7 2 0 0 2 2 2 0 TGS domain Adap_comp_sub PF00928.21 KFR05796.1 - 1.2e-37 129.8 0.0 1.4e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Sec10 PF07393.11 KFR05797.1 - 6.6e-153 510.8 30.5 7.1e-151 504.0 22.7 3.5 2 1 0 2 2 2 1 Exocyst complex component Sec10 V_ATPase_I PF01496.19 KFR05797.1 - 0.36 8.7 16.9 0.03 12.2 12.2 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Phasin PF05597.11 KFR05797.1 - 1.4 8.9 8.2 1.7 8.6 0.9 3.8 4 0 0 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) EF-G-binding_N PF07299.11 KFR05797.1 - 2.5 8.7 9.5 4.4 7.9 2.9 3.6 2 1 0 2 2 2 0 Elongation factor G-binding protein, N-terminal BLOC1_2 PF10046.9 KFR05797.1 - 5.9 7.3 10.8 0.17 12.2 2.7 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMPIT PF07851.13 KFR05797.1 - 5.9 6.0 12.5 5.8 6.1 3.5 2.8 3 0 0 3 3 3 0 TMPIT-like protein Jnk-SapK_ap_N PF09744.9 KFR05797.1 - 6.9 6.9 19.7 0.059 13.6 9.4 2.7 3 2 0 3 3 3 0 JNK_SAPK-associated protein-1 Cnn_1N PF07989.11 KFR05797.1 - 8.3 6.6 12.6 8.2 6.7 1.2 3.4 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 TF_Otx PF03529.13 KFR05798.1 - 3.7e-33 113.8 14.8 3.7e-33 113.8 14.8 2.7 2 1 1 3 3 3 1 Otx1 transcription factor Homeodomain PF00046.29 KFR05798.1 - 0.026 14.4 2.3 0.042 13.7 2.3 1.4 1 0 0 1 1 1 0 Homeodomain NUDE_C PF04880.13 KFR05798.1 - 0.52 10.8 6.2 0.099 13.1 2.9 1.4 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Hamartin PF04388.12 KFR05798.1 - 2.5 6.6 6.6 2.9 6.4 6.6 1.1 1 0 0 1 1 1 0 Hamartin protein DUF2723 PF11028.8 KFR05801.1 - 9.8e-37 126.5 4.5 2.9e-36 124.9 4.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2723) Pellino PF04710.14 KFR05802.1 - 6.6e-218 723.3 0.1 7.4e-218 723.2 0.1 1.0 1 0 0 1 1 1 1 Pellino Prok-RING_4 PF14447.6 KFR05802.1 - 0.0052 16.6 8.7 1.5 8.7 3.9 3.5 2 1 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFR05802.1 - 0.013 15.3 9.0 0.35 10.8 0.9 3.3 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFR05802.1 - 0.55 10.2 0.1 0.55 10.2 0.1 3.6 3 1 1 4 4 4 0 zinc-RING finger domain zf-RING_2 PF13639.6 KFR05802.1 - 1.2 9.5 13.2 0.64 10.4 0.5 3.2 3 1 0 3 3 3 0 Ring finger domain TBP PF00352.21 KFR05805.1 - 1e-64 214.5 0.4 2.6e-32 110.6 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KFR05805.1 - 6.1e-05 23.1 0.0 0.37 10.9 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Atg14 PF10186.9 KFR05806.1 - 3.1e-56 190.8 5.8 3.9e-56 190.5 5.8 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.14 KFR05806.1 - 0.009 15.9 6.6 0.067 13.0 8.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF724) Exonuc_VII_L PF02601.15 KFR05806.1 - 0.35 10.4 6.5 0.72 9.4 6.5 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit F-box-like PF12937.7 KFR05807.1 - 5.5e-05 23.0 0.0 0.00015 21.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like BTK PF00779.19 KFR05807.1 - 0.0025 17.6 1.2 0.0025 17.6 1.2 1.9 2 0 0 2 2 2 1 BTK motif F-box PF00646.33 KFR05807.1 - 0.0099 15.7 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain GKAP PF03359.13 KFR05808.1 - 1.6e-28 100.3 1.9 1.6e-28 100.3 1.9 3.2 2 1 0 3 3 3 1 Guanylate-kinase-associated protein (GKAP) protein FRB_dom PF08771.11 KFR05808.1 - 0.13 12.7 1.6 0.41 11.1 1.6 1.9 1 0 0 1 1 1 0 FKBP12-rapamycin binding domain Gal-bind_lectin PF00337.22 KFR05809.1 - 2.2e-36 124.3 0.0 2.8e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin MISS PF15822.5 KFR05810.1 - 8.5e-99 330.2 118.4 9.6e-99 330.1 118.4 1.0 1 0 0 1 1 1 1 MAPK-interacting and spindle-stabilising protein-like SOCS PF12610.8 KFR05811.1 - 1.4e-20 73.4 2.5 4.2e-20 71.9 2.5 1.8 1 0 0 1 1 1 1 Suppressor of cytokine signalling SOCS_box PF07525.16 KFR05811.1 - 1.2e-10 41.5 0.1 2.4e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 SOCS box SH2 PF00017.24 KFR05811.1 - 2.5e-08 33.9 0.0 7.7e-08 32.3 0.0 2.0 2 0 0 2 2 2 1 SH2 domain Mcl1_mid PF12341.8 KFR05812.1 - 4e-98 328.4 0.0 9.1e-98 327.3 0.0 1.6 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KFR05812.1 - 1.5e-21 76.3 7.7 4.2e-07 30.6 0.1 6.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR05812.1 - 2e-10 40.8 0.9 0.00012 22.3 0.1 4.4 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain HMG_box PF00505.19 KFR05812.1 - 5e-08 33.2 1.4 2.5e-07 31.0 0.1 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box eIF2A PF08662.11 KFR05812.1 - 6e-06 26.3 0.1 0.00018 21.4 0.0 2.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KFR05812.1 - 0.00018 20.3 0.2 0.072 11.7 0.1 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 HMG_box_2 PF09011.10 KFR05812.1 - 0.011 16.3 4.6 0.023 15.3 0.9 2.7 2 0 0 2 2 2 0 HMG-box domain Hira PF07569.11 KFR05812.1 - 0.016 14.9 0.3 4.5 6.9 0.0 2.9 2 0 0 2 2 2 0 TUP1-like enhancer of split Ge1_WD40 PF16529.5 KFR05812.1 - 0.15 11.0 2.3 14 4.6 0.1 3.4 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein GTP_cyclohydroI PF01227.22 KFR05813.1 - 1.1e-63 214.0 0.5 1.2e-63 213.7 0.5 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KFR05813.1 - 0.00066 19.8 0.0 0.0014 18.8 0.0 1.5 1 1 0 1 1 1 1 QueF-like protein MAPKK1_Int PF08923.10 KFR05813.1 - 0.038 13.8 0.1 0.047 13.5 0.1 1.2 1 0 0 1 1 1 0 Mitogen-activated protein kinase kinase 1 interacting SAM_1 PF00536.30 KFR05814.1 - 7.7e-09 35.9 0.1 1.5e-08 35.0 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PHAT PF09246.10 KFR05814.1 - 0.00011 22.0 0.1 0.074 12.9 0.0 3.0 3 0 0 3 3 3 2 PHAT SAM_2 PF07647.17 KFR05814.1 - 0.012 15.7 0.0 0.034 14.3 0.0 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) zf-C3HC4_3 PF13920.6 KFR05815.1 - 1.2e-11 44.3 10.9 2.9e-11 43.0 10.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFR05815.1 - 0.00014 21.7 10.5 0.00042 20.1 10.5 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 CDKN3 PF05706.12 KFR05816.1 - 1.1e-71 239.8 1.3 1.4e-71 239.6 1.3 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 KFR05816.1 - 3.7e-07 30.0 0.0 4.7e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFR05816.1 - 3.2e-05 23.8 0.0 4.5e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain ANF_receptor PF01094.28 KFR05816.1 - 0.022 13.9 0.0 0.03 13.4 0.0 1.1 1 0 0 1 1 1 0 Receptor family ligand binding region PTPlike_phytase PF14566.6 KFR05816.1 - 0.16 12.1 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate TGFb_propeptide PF00688.18 KFR05817.1 - 6.7e-54 183.2 0.9 9e-54 182.8 0.9 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 KFR05817.1 - 6.2e-34 117.1 0.5 1.3e-33 116.1 0.5 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain Tnp_DNA_bind PF14706.6 KFR05817.1 - 0.048 13.5 0.0 2.1 8.3 0.0 2.7 2 0 0 2 2 2 0 Transposase DNA-binding DDHD PF02862.17 KFR05818.1 - 1.7e-49 169.0 0.0 4.3e-49 167.7 0.0 1.7 1 0 0 1 1 1 1 DDHD domain DUF676 PF05057.14 KFR05818.1 - 0.088 12.3 0.0 3.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Acetyltransf_1 PF00583.25 KFR05819.1 - 2.4e-10 40.7 0.0 3.1e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFR05819.1 - 8.1e-08 32.3 0.0 1.1e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFR05819.1 - 2.6e-07 31.0 0.0 3.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFR05819.1 - 0.11 12.7 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DSPc PF00782.20 KFR05820.1 - 2e-38 131.2 0.0 2.4e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFR05820.1 - 0.1 12.2 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase AAA PF00004.29 KFR05821.1 - 7.2e-44 149.4 0.0 1.3e-43 148.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFR05821.1 - 6.3e-12 45.1 0.1 1.5e-11 43.9 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KFR05821.1 - 7.1e-10 38.7 0.6 1.4e-09 37.8 0.0 1.8 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 KFR05821.1 - 6.2e-07 30.0 0.1 0.00051 20.5 0.1 2.6 1 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KFR05821.1 - 4.2e-06 26.8 0.2 0.00011 22.2 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFR05821.1 - 6e-06 26.5 0.0 7.2e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFR05821.1 - 7.1e-06 26.3 0.2 0.0026 18.1 0.0 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KFR05821.1 - 1.8e-05 24.5 0.0 4.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KFR05821.1 - 0.00049 20.6 0.0 0.0019 18.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain Prot_ATP_OB_N PF17758.1 KFR05821.1 - 0.00053 19.6 0.2 0.0019 17.8 0.0 1.9 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_33 PF13671.6 KFR05821.1 - 0.0014 18.8 0.0 0.0029 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KFR05821.1 - 0.003 17.1 0.0 0.0058 16.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 KFR05821.1 - 0.0032 16.7 0.0 0.012 14.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_3 PF07726.11 KFR05821.1 - 0.0056 16.6 0.0 0.022 14.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KFR05821.1 - 0.007 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KFR05821.1 - 0.0074 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFR05821.1 - 0.0074 16.0 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KFR05821.1 - 0.0083 16.5 0.0 0.02 15.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 KFR05821.1 - 0.01 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 KFR05821.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Thymidylate_kin PF02223.17 KFR05821.1 - 0.021 14.5 0.1 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase AAA_24 PF13479.6 KFR05821.1 - 0.022 14.5 0.0 0.058 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KFR05821.1 - 0.041 13.2 0.1 0.5 9.7 0.0 2.5 3 0 0 3 3 3 0 KaiC NACHT PF05729.12 KFR05821.1 - 0.052 13.5 0.0 0.18 11.7 0.0 1.8 1 1 1 2 2 2 0 NACHT domain AAA_11 PF13086.6 KFR05821.1 - 0.076 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KFR05821.1 - 0.084 12.4 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KFR05821.1 - 0.11 12.4 0.0 0.8 9.6 0.0 2.4 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 KFR05821.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KFR05821.1 - 0.15 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ERO1 PF04137.15 KFR05822.1 - 2.4e-124 415.1 0.0 2.7e-124 414.9 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DUF1084 PF06454.11 KFR05823.1 - 0.028 13.8 13.5 0.081 12.3 13.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1084) DUF389 PF04087.14 KFR05823.1 - 0.44 10.6 4.6 0.23 11.5 1.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF389) Thioredoxin_6 PF13848.6 KFR05824.1 - 4.4e-24 85.4 0.0 1.2e-19 70.9 0.0 3.8 4 1 1 5 5 5 3 Thioredoxin-like domain Thioredoxin PF00085.20 KFR05824.1 - 6.2e-14 51.8 0.0 3.7e-13 49.3 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin 7tm_1 PF00001.21 KFR05825.1 - 0.00046 19.6 0.0 0.00053 19.4 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PRIMA1 PF16101.5 KFR05825.1 - 0.17 11.9 5.1 0.26 11.3 5.1 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DEC-1_N PF04625.13 KFR05825.1 - 1.3 8.0 4.8 1.3 8.0 4.8 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Tad PF13400.6 KFR05825.1 - 5.1 7.5 8.2 3.3 8.1 0.2 2.6 3 0 0 3 3 3 0 Putative Flp pilus-assembly TadE/G-like G2F PF07474.12 KFR05826.1 - 5.7e-63 212.0 0.0 8.1e-63 211.5 0.0 1.2 1 0 0 1 1 1 1 G2F domain Ldl_recept_b PF00058.17 KFR05826.1 - 3.5e-33 113.8 0.2 4.2e-13 49.5 0.0 4.6 5 0 0 5 5 5 3 Low-density lipoprotein receptor repeat class B EGF_3 PF12947.7 KFR05826.1 - 3e-24 84.9 75.1 3.6e-09 36.7 8.2 5.4 5 0 0 5 5 5 5 EGF domain NIDO PF06119.14 KFR05826.1 - 7.5e-22 78.1 0.0 2e-21 76.7 0.0 1.8 1 0 0 1 1 1 1 Nidogen-like Thyroglobulin_1 PF00086.18 KFR05826.1 - 1.1e-18 66.7 4.7 1.1e-18 66.7 4.7 2.5 2 0 0 2 2 1 1 Thyroglobulin type-1 repeat EGF_CA PF07645.15 KFR05826.1 - 6.7e-18 64.6 68.4 6.4e-10 39.1 4.9 5.5 5 0 0 5 5 4 4 Calcium-binding EGF domain cEGF PF12662.7 KFR05826.1 - 1.3e-11 44.2 45.8 4.8e-05 23.2 1.0 5.2 5 0 0 5 5 4 4 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFR05826.1 - 8.3e-07 29.2 71.0 0.00029 21.0 6.5 5.6 4 1 1 5 5 5 4 Coagulation Factor Xa inhibitory site EGF PF00008.27 KFR05826.1 - 1.2e-06 28.7 70.4 0.0076 16.5 9.5 5.8 5 0 0 5 5 5 4 EGF-like domain SGL PF08450.12 KFR05826.1 - 8.5e-05 22.2 0.0 0.0041 16.7 0.0 3.2 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Plasmod_Pvs28 PF06247.11 KFR05826.1 - 0.01 16.1 1.5 0.01 16.1 1.5 4.0 3 0 0 3 3 3 0 Pvs28 EGF domain hEGF PF12661.7 KFR05826.1 - 0.11 13.1 54.4 1.4 9.7 5.2 6.3 5 0 0 5 5 5 0 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 KFR05826.1 - 1.1 9.4 56.8 0.51 10.4 0.6 5.5 5 0 0 5 5 5 0 MSP1 EGF domain 1 RLL PF10036.9 KFR05827.1 - 4.5e-83 279.0 1.6 5.1e-83 278.9 1.6 1.0 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein Cactin_mid PF10312.9 KFR05827.1 - 0.0015 18.3 0.3 0.0021 17.8 0.3 1.1 1 0 0 1 1 1 1 Conserved mid region of cactin G-gamma PF00631.22 KFR05829.1 - 3.7e-20 71.7 0.0 4e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 GGL domain FtsX_ECD PF18075.1 KFR05829.1 - 0.016 15.8 0.1 0.019 15.6 0.1 1.0 1 0 0 1 1 1 0 FtsX extracellular domain CP12 PF02672.15 KFR05829.1 - 0.027 15.2 0.2 0.034 14.9 0.2 1.2 1 0 0 1 1 1 0 CP12 domain CHASE8 PF17152.4 KFR05829.1 - 0.089 13.0 0.1 0.097 12.9 0.1 1.1 1 0 0 1 1 1 0 Periplasmic sensor domain Thioredoxin PF00085.20 KFR05830.1 - 8.5e-18 64.2 0.0 1.1e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KFR05830.1 - 0.00037 19.9 0.0 0.00049 19.5 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KFR05830.1 - 0.016 15.7 0.1 0.035 14.6 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain KaiB PF07689.12 KFR05830.1 - 0.17 11.7 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 KaiB domain CcmD PF04995.14 KFR05830.1 - 0.31 11.2 1.4 0.51 10.5 1.4 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) fn3 PF00041.21 KFR05831.1 - 4.4e-10 39.8 0.0 9.1e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain SPRY PF00622.28 KFR05831.1 - 3.2e-08 33.7 0.0 5.5e-07 29.7 0.0 2.2 1 1 0 1 1 1 1 SPRY domain PRY PF13765.6 KFR05831.1 - 0.00038 20.0 0.1 0.0014 18.2 0.1 2.0 1 1 0 1 1 1 1 SPRY-associated domain ATP-synt_E_2 PF08112.11 KFR05831.1 - 0.18 12.1 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 ATP synthase epsilon subunit DUF2203 PF09969.9 KFR05831.1 - 0.19 12.5 1.5 0.34 11.6 1.5 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Phosphorylase PF00343.20 KFR05832.1 - 0 1126.2 0.0 0 1126.0 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Hydrolase_4 PF12146.8 KFR05833.1 - 5.3e-18 65.2 0.1 5.9e-14 51.9 0.1 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFR05833.1 - 3.9e-17 62.8 0.2 3.2e-15 56.5 0.2 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFR05833.1 - 1.6e-11 45.2 0.0 4e-10 40.7 0.2 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KFR05833.1 - 3.2e-06 27.2 0.0 4.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KFR05833.1 - 0.00064 19.9 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.21 KFR05833.1 - 0.019 14.4 0.0 0.063 12.8 0.0 1.9 1 1 0 1 1 1 0 Prolyl oligopeptidase family Lipase_3 PF01764.25 KFR05833.1 - 0.048 13.5 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.16 KFR05833.1 - 0.048 13.5 0.1 16 5.2 0.1 3.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Cutinase PF01083.22 KFR05833.1 - 0.078 12.9 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Cutinase Say1_Mug180 PF10340.9 KFR05833.1 - 0.12 11.2 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase LIDHydrolase PF10230.9 KFR05833.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.5 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase VirJ PF06057.11 KFR05833.1 - 0.18 11.6 0.0 0.27 11.1 0.0 1.1 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) SOAR PF16533.5 KFR05834.1 - 0.0022 17.9 11.7 0.0022 17.9 11.7 6.8 3 2 3 7 7 7 1 STIM1 Orai1-activating region DUF4482 PF14818.6 KFR05834.1 - 0.0057 17.5 4.6 0.0057 17.5 4.6 8.0 3 2 4 8 8 8 1 Domain of unknown function (DUF4482) Filament PF00038.21 KFR05834.1 - 0.042 13.4 127.9 0.023 14.3 26.9 5.2 2 1 3 5 5 5 0 Intermediate filament protein Baculo_PEP_C PF04513.12 KFR05834.1 - 0.43 10.6 0.0 0.43 10.6 0.0 6.9 4 3 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus BST2 PF16716.5 KFR05835.1 - 0.0015 19.1 8.3 0.002 18.7 8.3 1.1 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 UPF0240 PF06784.11 KFR05835.1 - 0.026 14.6 4.3 0.032 14.3 4.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) GAS PF13851.6 KFR05835.1 - 0.035 13.5 14.6 0.49 9.7 7.1 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ISG65-75 PF11727.8 KFR05835.1 - 0.058 12.6 5.2 0.064 12.5 5.2 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein TMEM237 PF15383.6 KFR05835.1 - 0.079 12.1 0.8 0.08 12.0 0.8 1.0 1 0 0 1 1 1 0 Transmembrane protein 237 Jnk-SapK_ap_N PF09744.9 KFR05835.1 - 0.32 11.2 12.0 1.4 9.1 2.4 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 KIAA1430 PF13879.6 KFR05835.1 - 0.55 11.0 10.6 2 9.2 10.6 1.9 1 1 0 1 1 1 0 KIAA1430 homologue XhlA PF10779.9 KFR05835.1 - 0.85 9.9 10.5 3.7 7.8 0.7 2.6 2 1 1 3 3 3 0 Haemolysin XhlA GTP-bdg_M PF16360.5 KFR05835.1 - 1.5 9.4 7.4 0.56 10.9 1.0 2.5 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region DUF1664 PF07889.12 KFR05835.1 - 1.9 8.5 7.3 4.1 7.5 7.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) YabA PF06156.13 KFR05835.1 - 6.5 7.5 11.6 11 6.7 11.6 1.4 1 1 0 1 1 1 0 Initiation control protein YabA Occludin_ELL PF07303.13 KFR05835.1 - 7.4 7.4 11.2 7.8 7.3 6.2 2.0 1 1 1 2 2 2 0 Occludin homology domain WW PF00397.26 KFR05836.1 - 6.9e-16 58.0 14.1 5.3e-10 39.2 4.3 3.5 3 0 0 3 3 3 2 WW domain Suppressor_APC PF11414.8 KFR05836.1 - 2.3 8.4 7.1 1.2 9.3 2.7 2.3 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein GBP PF02263.19 KFR05837.1 - 1.1e-97 326.3 0.1 1.5e-97 325.9 0.1 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 KFR05837.1 - 3.4e-06 26.7 0.1 5.4e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain Tiam_CC_Ex PF18385.1 KFR05837.1 - 0.0064 16.9 0.0 0.025 15.0 0.0 1.9 1 0 0 1 1 1 1 T-lymphoma invasion and metastasis CC-Ex domain CNH PF00780.22 KFR05838.1 - 3.7e-77 259.6 0.8 6.8e-77 258.8 0.8 1.4 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.25 KFR05838.1 - 8.5e-63 212.2 0.0 1.3e-62 211.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR05838.1 - 1.1e-38 133.0 0.0 1.9e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFR05838.1 - 0.0001 21.2 0.0 0.00016 20.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFR05838.1 - 0.0082 15.5 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 KFR05840.1 - 2.2e-62 210.8 0.0 2.6e-62 210.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR05840.1 - 2.8e-27 95.6 0.1 2.9e-26 92.3 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFR05840.1 - 0.0002 20.4 0.0 0.00027 20.0 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFR05840.1 - 0.059 13.3 0.3 0.39 10.6 0.1 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFR05840.1 - 0.097 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 LRR_4 PF12799.7 KFR05841.1 - 0.045 14.2 4.4 0.11 13.0 0.3 3.1 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) DAO PF01266.24 KFR05842.1 - 1.5e-66 225.4 0.0 2e-66 225.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFR05842.1 - 0.00067 19.0 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KFR05842.1 - 0.0015 18.7 0.2 0.0045 17.2 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFR05842.1 - 0.0056 16.0 0.0 0.23 10.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFR05842.1 - 0.027 13.7 0.1 0.43 9.8 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 KFR05842.1 - 0.051 12.6 0.1 0.12 11.4 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Mqo PF06039.15 KFR05842.1 - 0.061 11.9 0.0 0.32 9.5 0.0 2.0 3 0 0 3 3 3 0 Malate:quinone oxidoreductase (Mqo) RasGEF PF00617.19 KFR05843.1 - 6.5e-50 169.8 0.4 1.4e-49 168.7 0.4 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KFR05843.1 - 2.5e-31 108.0 1.1 1e-30 106.1 0.1 2.5 3 0 0 3 3 3 1 RasGEF N-terminal motif RhoGEF PF00621.20 KFR05843.1 - 1.2e-14 55.0 1.3 1.2e-14 55.0 1.3 2.7 3 1 1 4 4 4 1 RhoGEF domain PH PF00169.29 KFR05843.1 - 1.1e-11 45.2 0.6 5.6e-11 42.9 0.1 2.4 2 0 0 2 2 2 1 PH domain Histone PF00125.24 KFR05843.1 - 4.2e-10 40.1 0.0 9.7e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 IQ_SEC7_PH PF16453.5 KFR05843.1 - 0.00013 22.0 0.0 0.00037 20.5 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 KFR05843.1 - 0.0038 17.1 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_10 PF15411.6 KFR05843.1 - 0.011 16.0 0.2 0.038 14.3 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain PH_9 PF15410.6 KFR05843.1 - 0.051 14.0 0.1 0.19 12.1 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain Methyltransf_16 PF10294.9 KFR05844.1 - 1e-28 100.3 0.0 1.2e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KFR05844.1 - 0.039 13.8 0.0 0.041 13.7 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Arf PF00025.21 KFR05845.1 - 4e-77 257.6 0.0 4.5e-77 257.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFR05845.1 - 3e-15 56.5 0.0 4e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFR05845.1 - 1.9e-14 53.6 0.0 2.1e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFR05845.1 - 3e-13 49.6 0.0 3.7e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFR05845.1 - 2e-12 46.9 1.0 4e-08 32.8 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KFR05845.1 - 1.3e-10 41.1 0.0 1.6e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFR05845.1 - 9.5e-05 22.5 0.0 0.00014 22.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KFR05845.1 - 0.01 15.1 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase SpoOE-like PF09388.10 KFR05845.1 - 0.021 14.7 1.2 0.038 13.9 1.2 1.4 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein CRISPR_Cas2 PF09827.9 KFR05845.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 CRISPR associated protein Cas2 FbpA PF05833.11 KFR05846.1 - 1.8e-35 122.6 17.0 4.9e-35 121.2 17.0 1.7 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 KFR05846.1 - 1.2e-33 116.1 0.6 1.3e-32 112.7 0.0 2.5 2 0 0 2 2 2 1 NFACT protein RNA binding domain NFACT-C PF11923.8 KFR05846.1 - 1.2e-23 83.0 0.8 7.6e-14 51.5 0.2 4.7 4 2 1 5 5 5 2 NFACT protein C-terminal domain TetR_C_21 PF17926.1 KFR05846.1 - 1.2 9.3 5.5 0.54 10.4 1.2 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF948 PF06103.11 KFR05846.1 - 3.8 7.8 4.6 2.4 8.5 1.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Kelch_4 PF13418.6 KFR05847.1 - 2e-25 88.5 21.7 2.4e-09 37.0 0.1 7.7 5 2 2 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KFR05847.1 - 2.8e-25 87.8 16.9 1.5e-05 24.9 0.1 7.6 7 2 0 7 7 7 6 Kelch motif Kelch_1 PF01344.25 KFR05847.1 - 2.1e-23 81.6 17.5 1.1e-06 28.1 0.3 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KFR05847.1 - 5.4e-22 77.6 13.1 6.8e-08 32.6 0.2 7.4 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KFR05847.1 - 7.1e-19 67.4 13.0 6.5e-06 26.3 0.0 6.7 7 0 0 7 7 7 3 Kelch motif Kelch_2 PF07646.15 KFR05847.1 - 1.6e-14 53.2 19.0 0.00015 21.6 0.0 6.9 6 1 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KFR05848.1 - 4e-27 94.0 19.0 1.1e-07 31.8 0.4 6.7 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KFR05848.1 - 2.3e-24 85.2 16.9 4.1e-08 33.3 0.1 5.8 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KFR05848.1 - 6.4e-24 83.4 20.3 5.4e-06 26.5 0.3 6.8 3 2 3 6 6 6 4 Kelch motif Kelch_1 PF01344.25 KFR05848.1 - 1.6e-18 66.0 11.5 9.5e-06 25.1 0.1 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KFR05848.1 - 2.7e-17 62.0 18.5 2.8e-06 27.1 0.0 6.1 5 2 1 6 6 6 5 Kelch motif Kelch_5 PF13854.6 KFR05848.1 - 5.7e-17 61.3 6.8 0.00082 19.3 0.1 6.3 6 1 0 6 6 6 4 Kelch motif DNA_pol_E_B PF04042.16 KFR05849.1 - 6.8e-52 175.9 0.5 1.1e-51 175.3 0.5 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.8 KFR05849.1 - 2.9e-19 69.1 2.2 5.7e-19 68.2 2.2 1.5 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal MGAT2 PF05060.14 KFR05851.1 - 3.1e-135 450.8 0.2 3.4e-135 450.6 0.2 1.0 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) LRR_4 PF12799.7 KFR05852.1 - 2.8e-15 56.2 13.5 4.9e-07 30.0 1.6 4.5 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFR05852.1 - 1.2e-14 53.7 14.3 1.1e-06 28.3 1.8 3.4 3 0 0 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 KFR05852.1 - 0.0009 19.1 8.1 0.45 10.7 0.2 4.9 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 KFR05852.1 - 0.063 13.8 25.2 0.49 11.1 0.0 7.3 7 1 0 7 7 7 0 Leucine Rich Repeat Ribosomal_S14 PF00253.21 KFR05853.1 - 2.2e-15 56.2 2.9 2.3e-15 56.0 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.6 KFR05853.1 - 0.056 13.4 0.3 0.07 13.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) SANTA PF09133.10 KFR05854.1 - 2.5e-19 69.5 0.2 2.7e-19 69.4 0.2 1.0 1 0 0 1 1 1 1 SANTA (SANT Associated) Myb_DNA-binding PF00249.31 KFR05855.1 - 0.0072 16.5 0.0 0.02 15.1 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFR05855.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain FANCM-MHF_bd PF16783.5 KFR05856.1 - 5.7e-48 161.8 4.2 2.1e-47 160.0 4.2 2.1 1 0 0 1 1 1 1 FANCM to MHF binding domain Helicase_C PF00271.31 KFR05856.1 - 9.3e-19 67.8 2.0 4e-18 65.8 0.1 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC4 PF02732.15 KFR05856.1 - 8e-10 39.1 0.6 4.2e-09 36.8 0.6 2.4 1 0 0 1 1 1 1 ERCC4 domain DEAD PF00270.29 KFR05856.1 - 3.1e-05 23.8 0.0 8e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFR05856.1 - 0.00012 22.2 0.0 0.00043 20.3 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Rad10 PF03834.14 KFR05856.1 - 0.12 12.4 0.1 0.35 10.9 0.1 1.7 1 0 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) SOUL PF04832.12 KFR05857.1 - 2.5e-36 125.4 0.0 3.3e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 SOUL heme-binding protein TPR_14 PF13428.6 KFR05858.1 - 3.6e-12 46.0 0.3 3.5 8.7 0.0 7.1 6 1 2 8 8 8 4 Tetratricopeptide repeat Suf PF05843.14 KFR05858.1 - 0.00015 21.8 5.5 0.0042 17.1 0.1 3.6 3 1 1 4 4 4 1 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 KFR05858.1 - 0.00018 21.5 7.7 0.51 10.3 0.5 5.1 4 2 1 5 5 5 2 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 KFR05858.1 - 0.0003 21.0 1.3 0.55 10.6 0.2 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFR05858.1 - 0.00032 21.3 0.0 0.067 13.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFR05858.1 - 0.0014 19.1 0.0 6.4 7.4 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFR05858.1 - 0.0068 16.4 4.8 3.3 8.1 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFR05858.1 - 0.074 13.7 0.9 96 4.0 0.0 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFR05858.1 - 1 9.3 3.4 33 4.5 0.2 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat CLASP_N PF12348.8 KFR05859.1 - 3e-12 46.6 1.8 2.8e-05 23.8 0.1 3.4 3 0 0 3 3 3 3 CLASP N terminal HEAT PF02985.22 KFR05859.1 - 0.0054 16.9 2.9 25 5.5 0.1 5.6 5 0 0 5 5 5 1 HEAT repeat ParcG PF10274.9 KFR05859.1 - 0.031 14.4 0.3 0.43 10.7 0.2 2.5 2 0 0 2 2 2 0 Parkin co-regulated protein NUC173 PF08161.12 KFR05859.1 - 0.041 13.5 2.6 6.2 6.4 0.1 3.2 3 0 0 3 3 3 0 NUC173 domain DUF2682 PF10909.8 KFR05859.1 - 0.19 12.3 0.5 1.6 9.3 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2682) Adaptin_N PF01602.20 KFR05859.1 - 0.41 9.1 3.7 0.3 9.6 0.3 2.4 3 1 0 3 3 3 0 Adaptin N terminal region DUF1682 PF07946.14 KFR05859.1 - 1.8 7.7 7.0 4.5 6.4 7.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) LRR_8 PF13855.6 KFR05860.1 - 3.9e-37 125.8 29.1 4.2e-14 52.1 12.2 3.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFR05860.1 - 1.8e-17 63.2 17.3 8.7e-06 26.0 0.1 4.6 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) I-set PF07679.16 KFR05860.1 - 1.8e-15 56.7 0.0 3.8e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_5 PF13306.6 KFR05860.1 - 3e-15 56.3 0.1 1e-14 54.6 0.1 1.9 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) Ig_3 PF13927.6 KFR05860.1 - 2.2e-13 50.6 0.0 5.1e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFR05860.1 - 1e-09 38.4 0.0 2e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.33 KFR05860.1 - 1.1e-09 37.5 8.5 0.95 10.3 0.0 6.7 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_9 PF14580.6 KFR05860.1 - 6.6e-09 35.5 5.7 5.6e-05 22.7 3.7 2.4 1 1 1 2 2 2 2 Leucine-rich repeat Ig_2 PF13895.6 KFR05860.1 - 8.7e-07 29.2 0.0 2.2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.21 KFR05860.1 - 0.00046 20.5 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain C2-set_2 PF08205.12 KFR05860.1 - 0.0094 16.0 0.0 0.027 14.5 0.0 1.8 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain LSR PF05624.14 KFR05860.1 - 0.013 15.4 1.5 0.013 15.4 1.5 2.5 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) V-set PF07686.17 KFR05860.1 - 0.025 14.7 0.0 6.5 7.0 0.0 2.4 1 1 1 2 2 2 0 Immunoglobulin V-set domain DUF240 PF03086.14 KFR05860.1 - 0.12 12.3 4.6 0.2 11.6 3.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF240) Keratin PF02422.16 KFR05868.1 - 7.6e-34 115.3 13.7 8.2e-34 115.2 13.7 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFR05870.1 - 2.4e-36 123.3 16.4 2.6e-36 123.2 16.4 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFR05871.1 - 2.4e-36 123.3 16.4 2.6e-36 123.2 16.4 1.0 1 0 0 1 1 1 1 Keratin Lipocalin PF00061.23 KFR05872.1 - 4.1e-17 62.7 0.0 5.4e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.12 KFR05872.1 - 8.4e-10 38.7 0.0 1.4e-09 38.0 0.0 1.3 1 1 0 1 1 1 1 Lipocalin-like domain Triabin PF03973.13 KFR05872.1 - 2.3e-05 24.3 0.1 0.00095 19.1 0.0 2.2 2 0 0 2 2 2 1 Triabin SNF2_N PF00176.23 KFR05879.1 - 2e-67 227.4 0.8 4e-67 226.4 0.8 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain CDH1_2_SANT_HL1 PF18375.1 KFR05879.1 - 3.7e-33 114.1 0.0 3.7e-33 114.1 0.0 5.3 4 1 1 5 5 5 1 CDH1/2 SANT-Helical linker 1 Chromo PF00385.24 KFR05879.1 - 1.7e-28 98.3 9.8 4.6e-18 64.9 0.1 4.1 4 0 0 4 4 4 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 KFR05879.1 - 3.3e-27 94.8 2.4 3.3e-27 94.8 2.4 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 KFR05879.1 - 1.3e-05 25.4 0.0 3.9e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CHDCT2 PF08074.11 KFR05879.1 - 0.0032 17.7 0.0 0.0032 17.7 0.0 2.9 3 0 0 3 3 3 1 CHDCT2 (NUC038) domain RGM_C PF06534.13 KFR05880.1 - 5.3e-70 234.4 0.0 7.5e-70 233.9 0.0 1.2 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) C-terminus RGM_N PF06535.12 KFR05880.1 - 7e-62 208.5 1.4 1e-61 208.0 1.4 1.2 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) N-terminus RIO1 PF01163.22 KFR05881.1 - 2e-53 180.8 2.1 2e-53 180.8 2.1 1.7 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.11 KFR05881.1 - 2.9e-24 85.1 1.3 7.1e-24 83.8 0.1 2.3 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 KFR05881.1 - 5.3e-09 36.3 3.3 2.8e-05 24.2 0.8 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KFR05881.1 - 1.5e-07 31.0 3.9 1.1e-06 28.1 2.1 2.8 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.11 KFR05881.1 - 0.0016 18.1 0.0 0.0029 17.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) PIP49_C PF12260.8 KFR05881.1 - 0.026 14.2 0.3 0.058 13.0 0.1 1.7 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 7tm_1 PF00001.21 KFR05908.1 - 1.1e-80 270.8 6.1 1.3e-80 270.6 6.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR05908.1 - 1.4e-18 67.2 4.8 1.9e-18 66.8 4.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFR05908.1 - 1.5e-09 37.9 10.2 3e-09 36.9 10.2 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFR05908.1 - 1.7e-07 30.9 0.5 2.9e-07 30.1 0.5 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFR05908.1 - 0.00025 20.9 5.8 0.003 17.3 4.3 2.3 2 0 0 2 2 2 1 Olfactory receptor Amidohydro_1 PF01979.20 KFR05909.1 - 4.3e-51 174.3 0.1 5.4e-51 173.9 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFR05909.1 - 1.9e-12 47.4 0.6 1.6e-07 31.2 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family BNIP3 PF06553.12 KFR05910.1 - 2.1e-85 285.3 2.5 2.4e-85 285.2 2.5 1.0 1 0 0 1 1 1 1 BNIP3 DUF3319 PF11782.8 KFR05910.1 - 0.027 14.4 0.1 0.047 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3319) WD40 PF00400.32 KFR05911.1 - 1.5e-10 41.5 1.7 2.8 9.0 0.1 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR05911.1 - 3.5e-05 24.0 0.1 2.9 8.3 0.0 4.5 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Y_phosphatase2 PF03162.13 KFR05911.1 - 0.041 13.5 0.4 1.4 8.5 0.0 2.6 2 0 0 2 2 2 0 Tyrosine phosphatase family COE1_HLH PF16423.5 KFR05912.1 - 7e-35 118.5 2.0 5.1e-28 96.5 0.3 2.5 2 0 0 2 2 2 2 Transcription factor COE1 helix-loop-helix domain COE1_DBD PF16422.5 KFR05912.1 - 1.5e-33 116.2 1.2 2e-33 115.8 1.2 1.2 1 0 0 1 1 1 1 Transcription factor COE1 DNA-binding domain TIG PF01833.24 KFR05912.1 - 4.8e-12 45.8 0.1 4.8e-12 45.8 0.1 2.3 3 0 0 3 3 3 1 IPT/TIG domain Pericardin_rpt PF07054.11 KFR05912.1 - 0.2 11.8 1.8 0.21 11.8 0.1 1.9 2 0 0 2 2 2 0 Pericardin like repeat PP1_bind PF15276.6 KFR05913.1 - 2.3e-19 69.4 0.4 2.8e-19 69.2 0.4 1.1 1 0 0 1 1 1 1 Protein phosphatase 1 binding Pentapeptide PF00805.22 KFR05914.1 - 1.2e-37 127.1 23.6 1.3e-12 47.1 1.9 4.6 2 2 1 4 4 4 4 Pentapeptide repeats (8 copies) BTB_2 PF02214.22 KFR05914.1 - 1.1e-20 73.7 0.0 1.9e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Pentapeptide_4 PF13599.6 KFR05914.1 - 3.6e-20 71.9 0.3 4.8e-07 29.9 0.0 3.2 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 KFR05914.1 - 2.9e-14 52.9 0.0 8.8e-06 25.8 0.0 4.4 1 1 0 3 3 3 3 Pentapeptide repeats (9 copies) KHA PF11834.8 KFR05914.1 - 1.6e-13 50.5 0.1 2.9e-13 49.7 0.1 1.4 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel BTB_3 PF16017.5 KFR05914.1 - 2.8e-05 24.2 0.0 5.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KFR05914.1 - 3.3e-05 24.1 0.0 7.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain GnRH PF00446.17 KFR05915.1 - 0.0011 19.1 5.2 0.0019 18.4 5.2 1.4 1 0 0 1 1 1 1 Gonadotropin-releasing hormone DHR-2 PF06920.13 KFR05916.1 - 4.8e-68 230.1 2.6 5.7e-68 229.9 2.6 1.1 1 0 0 1 1 1 1 Dock homology region 2 DUF1160 PF06648.11 KFR05916.1 - 0.014 15.4 0.1 0.05 13.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1160) DOCK-C2 PF14429.6 KFR05918.1 - 1.4e-35 122.8 0.1 2.5e-35 122.0 0.0 1.4 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DOCK_N PF16172.5 KFR05918.1 - 3.7e-11 42.6 0.0 4.9e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 DOCK N-terminus IRK_C PF17655.1 KFR05918.1 - 0.06 13.0 0.3 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 Inward rectifier potassium channel C-terminal domain Stanniocalcin PF03298.13 KFR05919.1 - 2.2e-100 334.0 5.9 2.7e-100 333.8 5.9 1.0 1 0 0 1 1 1 1 Stanniocalcin family Homeodomain PF00046.29 KFR05920.1 - 6.1e-21 74.0 5.2 1e-20 73.3 5.2 1.4 1 0 0 1 1 1 1 Homeodomain GDA1_CD39 PF01150.17 KFR05921.1 - 9.2e-96 321.1 0.0 1.2e-95 320.7 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Adhesin_E PF16747.5 KFR05921.1 - 0.12 12.5 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Surface-adhesin protein E Lysyl_oxidase PF01186.17 KFR05922.1 - 8.4e-100 332.6 4.4 1.7e-99 331.5 4.4 1.6 1 0 0 1 1 1 1 Lysyl oxidase SRCR PF00530.18 KFR05922.1 - 1.3e-93 308.0 44.2 5.4e-29 100.6 4.7 5.2 5 0 0 5 5 5 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFR05922.1 - 3.9e-22 78.6 17.6 3.5e-05 24.3 0.3 4.7 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFR05922.1 - 1.7e-15 57.5 7.7 0.0041 17.6 0.0 4.8 4 0 0 4 4 4 4 Hepsin, SRCR domain CARDB PF07705.11 KFR05922.1 - 0.087 13.1 0.1 0.53 10.6 0.1 2.2 2 0 0 2 2 2 0 CARDB R3H PF01424.22 KFR05923.1 - 9.3e-14 51.2 0.1 1.9e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 R3H domain NCBP3 PF10309.9 KFR05923.1 - 1.6e-06 27.8 0.0 3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 KFR05923.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA binding domain RgpF PF05045.12 KFR05923.1 - 0.29 9.8 0.0 0.38 9.5 0.0 1.1 1 0 0 1 1 1 0 Rhamnan synthesis protein F 7tm_1 PF00001.21 KFR05925.1 - 9.9e-74 248.0 13.0 1.2e-73 247.7 13.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR05925.1 - 2.4e-09 36.9 12.8 2.1e-08 33.9 12.8 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFR05925.1 - 2.8e-07 30.4 16.0 3.3e-07 30.2 9.8 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx DUF621 PF04789.15 KFR05925.1 - 0.0015 17.7 10.3 0.0015 17.7 10.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF621) Snf7 PF03357.21 KFR05926.1 - 1.5e-23 83.3 6.3 1.5e-23 83.3 6.3 2.1 2 0 0 2 2 2 1 Snf7 PspA_IM30 PF04012.12 KFR05926.1 - 8.6e-06 25.5 0.4 8.6e-06 25.5 0.4 2.2 2 0 0 2 2 2 1 PspA/IM30 family DUF763 PF05559.11 KFR05926.1 - 0.078 12.2 1.1 0.14 11.4 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Fez1 PF06818.15 KFR05926.1 - 0.12 12.8 9.8 0.03 14.8 4.9 2.1 1 1 1 2 2 2 0 Fez1 LPP PF04728.13 KFR05926.1 - 0.46 10.9 5.1 3.3 8.2 0.2 3.2 3 1 0 3 3 3 0 Lipoprotein leucine-zipper Apolipoprotein PF01442.18 KFR05926.1 - 0.48 10.3 7.9 5.5 6.8 8.9 2.3 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Fmp27_WPPW PF10359.9 KFR05926.1 - 0.71 8.7 4.3 1.1 8.0 4.0 1.4 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Snapin_Pallidin PF14712.6 KFR05926.1 - 0.99 9.9 10.1 1.2 9.6 2.9 3.5 3 1 0 3 3 3 0 Snapin/Pallidin RUN PF02759.19 KFR05926.1 - 1.2 9.1 5.3 9.1 6.2 0.2 3.1 2 1 1 3 3 3 0 RUN domain Death PF00531.22 KFR05927.1 - 7.3e-16 58.1 0.0 1.1e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Death domain TNFR_c6 PF00020.18 KFR05927.1 - 2.2e-11 43.9 39.1 9.7e-07 29.1 4.3 3.7 2 1 0 3 3 3 2 TNFR/NGFR cysteine-rich region PDZ PF00595.24 KFR05929.1 - 2.3e-15 56.7 0.0 3.8e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain DUF4749 PF15936.5 KFR05929.1 - 2.9e-10 41.1 0.1 1.1e-09 39.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4749) PDZ_6 PF17820.1 KFR05929.1 - 1.6e-07 31.0 0.2 2.9e-07 30.2 0.2 1.4 1 0 0 1 1 1 1 PDZ domain LIM PF00412.22 KFR05929.1 - 7e-06 26.2 1.7 1e-05 25.6 1.7 1.3 1 0 0 1 1 1 1 LIM domain PDZ_2 PF13180.6 KFR05929.1 - 6.9e-05 23.1 0.0 0.00012 22.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain zf_UBZ PF18439.1 KFR05929.1 - 0.15 11.7 2.9 3.5 7.3 0.1 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger SH3_1 PF00018.28 KFR05930.1 - 4.2e-16 58.3 0.1 4.4e-13 48.6 0.0 2.3 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KFR05930.1 - 1.1e-14 53.8 0.1 2.1e-14 52.9 0.0 1.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KFR05930.1 - 5e-14 51.9 0.1 5.2e-13 48.6 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain Metallophos PF00149.28 KFR05931.1 - 2.6e-35 122.8 0.0 4.4e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Piwi PF02171.17 KFR05932.1 - 4.2e-79 265.9 0.1 5.3e-79 265.6 0.1 1.1 1 0 0 1 1 1 1 Piwi domain ArgoL2 PF16488.5 KFR05932.1 - 0.1 12.9 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 Argonaute linker 2 domain RNA_pol_Rpc4 PF05132.14 KFR05933.1 - 3e-26 92.6 4.3 4.3e-26 92.1 0.8 2.6 2 1 0 2 2 2 1 RNA polymerase III RPC4 CKS PF01111.19 KFR05937.1 - 7e-27 93.5 1.5 7.9e-27 93.3 1.5 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit RVT_1 PF00078.27 KFR05938.1 - 0.0024 17.4 0.0 0.0048 16.4 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SIX1_SD PF16878.5 KFR05986.1 - 3.3e-42 143.5 0.1 7.6e-42 142.3 0.0 1.6 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain LRR_8 PF13855.6 KFR05995.1 - 1.7e-46 155.8 51.6 3.2e-14 52.4 2.8 5.4 2 2 4 6 6 6 6 Leucine rich repeat LRR_5 PF13306.6 KFR05995.1 - 2.3e-22 79.3 0.0 2.2e-14 53.5 0.1 2.7 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFR05995.1 - 1.4e-20 73.0 26.5 3.4e-07 30.5 1.1 6.1 2 2 2 6 6 6 5 Leucine Rich repeats (2 copies) I-set PF07679.16 KFR05995.1 - 6.9e-14 51.7 0.0 1.3e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFR05995.1 - 2.8e-11 43.4 2.5 3.7e-11 43.1 0.1 2.4 3 0 0 3 3 3 1 Immunoglobulin domain Ig_3 PF13927.6 KFR05995.1 - 6.6e-11 42.7 0.9 3.1e-10 40.5 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain LRR_9 PF14580.6 KFR05995.1 - 3.9e-08 33.0 9.1 9.1e-07 28.5 0.5 2.9 1 1 2 3 3 3 3 Leucine-rich repeat V-set PF07686.17 KFR05995.1 - 2.3e-07 30.9 0.9 1.9e-05 24.8 0.9 2.4 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KFR05995.1 - 2.5e-06 27.7 1.2 3.8e-06 27.2 0.1 1.9 2 0 0 2 2 2 1 Immunoglobulin domain LRR_1 PF00560.33 KFR05995.1 - 9.3e-05 22.5 31.5 0.54 11.0 0.0 9.2 8 1 1 9 9 9 2 Leucine Rich Repeat Ig_6 PF18452.1 KFR05995.1 - 0.00031 20.2 0.4 0.001 18.6 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain Podoplanin PF05808.11 KFR05995.1 - 0.024 14.7 5.5 0.052 13.7 5.5 1.6 1 0 0 1 1 1 0 Podoplanin LRR_6 PF13516.6 KFR05995.1 - 0.066 13.3 24.8 2.2 8.5 0.3 7.4 7 0 0 7 7 7 0 Leucine Rich repeat Insulin_TMD PF17870.1 KFR05995.1 - 0.12 12.4 0.7 0.31 11.1 0.7 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment LRRNT PF01462.18 KFR05995.1 - 6.7 6.5 12.6 0.044 13.4 3.0 2.5 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain API5 PF05918.11 KFR05996.1 - 2.3e-197 657.0 0.0 2.6e-197 656.8 0.0 1.0 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.6 KFR05996.1 - 9e-05 22.8 0.1 0.00035 20.9 0.1 1.9 2 0 0 2 2 2 1 HEAT repeats MMS19_N PF14500.6 KFR05996.1 - 0.018 14.6 2.2 0.13 11.9 2.2 2.2 1 1 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II Dak2 PF02734.17 KFR05996.1 - 0.024 14.5 0.0 0.071 13.0 0.0 1.7 1 1 0 1 1 1 0 DAK2 domain TPR_2 PF07719.17 KFR05997.1 - 6.8e-22 75.8 1.9 0.00077 19.4 0.0 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 KFR05997.1 - 1.9e-21 74.9 2.7 0.00029 20.5 0.1 7.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFR05997.1 - 4.3e-13 48.3 0.5 0.014 15.5 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFR05997.1 - 8e-12 44.3 7.8 0.032 14.3 0.0 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFR05997.1 - 2.8e-10 39.7 0.1 0.098 12.4 0.0 5.7 5 0 0 5 5 5 3 TPR repeat TPR_12 PF13424.6 KFR05997.1 - 1.2e-09 38.3 12.2 1.2 9.5 0.0 6.8 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFR05997.1 - 3.2e-08 33.7 0.0 0.79 10.7 0.0 5.6 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFR05997.1 - 6.3e-06 25.9 6.8 1.5 8.8 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFR05997.1 - 5.8e-05 23.2 0.2 0.1 12.8 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFR05997.1 - 0.00061 20.4 0.9 11 6.8 0.1 4.0 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFR05997.1 - 0.0022 18.5 1.4 3.1 8.4 0.0 4.7 4 1 2 6 6 6 1 Tetratricopeptide repeat ChAPs PF09295.10 KFR05997.1 - 0.0068 15.5 2.9 0.011 14.8 0.5 2.4 3 1 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.6 KFR05997.1 - 0.0092 16.0 1.5 1.9 8.6 0.1 3.2 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 KFR05997.1 - 0.017 15.3 1.7 0.095 12.9 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 BSD PF03909.17 KFR05997.1 - 0.13 12.3 0.3 7.3 6.7 0.0 2.7 2 0 0 2 2 2 0 BSD domain 2OG-FeII_Oxy_2 PF13532.6 KFR05998.1 - 6e-32 111.4 0.0 7.4e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RVT_1 PF00078.27 KFR05999.1 - 0.0018 17.8 0.0 0.0044 16.6 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Aminotran_1_2 PF00155.21 KFR06000.1 - 1.4e-59 202.1 0.0 2e-59 201.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KFR06000.1 - 0.0088 15.4 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Glyco_transf_64 PF09258.10 KFR06001.1 - 1.1e-98 329.5 0.2 1.5e-98 328.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 KFR06001.1 - 2.6e-57 194.3 0.0 3.6e-57 193.9 0.0 1.2 1 0 0 1 1 1 1 Exostosin family Homeodomain PF00046.29 KFR06002.1 - 6e-25 86.9 8.1 6.6e-25 86.7 6.1 2.0 2 0 0 2 2 2 1 Homeodomain OAR PF03826.17 KFR06002.1 - 7.4e-10 38.3 3.3 1.4e-09 37.4 3.3 1.5 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 KFR06002.1 - 0.00068 19.5 0.2 0.0014 18.5 0.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain Tetraspanin PF00335.20 KFR06003.1 - 3.1e-51 174.3 9.1 3.6e-51 174.1 9.1 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2981 PF11200.8 KFR06003.1 - 0.0012 18.7 3.6 0.0028 17.5 3.5 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF2981) GATase_5 PF13507.6 KFR06003.1 - 0.18 10.9 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Tetraspanin PF00335.20 KFR06004.1 - 2.7e-49 168.0 10.5 3e-49 167.8 10.5 1.0 1 0 0 1 1 1 1 Tetraspanin family p53-inducible11 PF14936.6 KFR06005.1 - 3.1e-90 301.1 1.1 3.5e-90 300.9 1.1 1.0 1 0 0 1 1 1 1 Tumour protein p53-inducible protein 11 DUF4345 PF14248.6 KFR06005.1 - 0.00086 19.2 3.3 0.0032 17.4 3.2 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4345) DUF3325 PF11804.8 KFR06005.1 - 0.007 16.5 1.7 0.052 13.7 1.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3325) zf-TRAF PF02176.18 KFR06011.1 - 1.3e-09 38.6 0.1 2.6e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 TRAF-type zinc finger zf-TRAF_2 PF15965.5 KFR06011.1 - 9.7e-06 26.0 0.2 2.1e-05 24.9 0.2 1.5 1 0 0 1 1 1 1 TRAF-like zinc-finger SlyX PF04102.12 KFR06011.1 - 0.00012 22.6 2.8 0.00012 22.6 2.8 2.2 2 0 0 2 2 2 1 SlyX Med21 PF11221.8 KFR06011.1 - 0.00019 21.7 0.4 0.00033 20.9 0.4 1.5 1 0 0 1 1 1 1 Subunit 21 of Mediator complex PspA_IM30 PF04012.12 KFR06011.1 - 0.0011 18.6 1.0 0.0011 18.6 1.0 1.8 2 0 0 2 2 2 1 PspA/IM30 family UPF0242 PF06785.11 KFR06011.1 - 0.004 17.3 1.5 0.0096 16.1 1.5 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus TSC22 PF01166.18 KFR06011.1 - 0.0042 17.4 2.1 2 8.8 0.1 3.0 1 1 2 3 3 3 1 TSC-22/dip/bun family Tropomyosin_1 PF12718.7 KFR06011.1 - 0.005 17.0 1.3 0.0087 16.2 1.3 1.3 1 0 0 1 1 1 1 Tropomyosin like DUF16 PF01519.16 KFR06011.1 - 0.017 15.6 2.6 0.056 13.9 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 CENP-F_leu_zip PF10473.9 KFR06011.1 - 0.017 15.1 1.5 0.042 13.9 1.5 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KFR06011.1 - 0.018 13.9 0.4 0.032 13.1 0.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein HMMR_N PF15905.5 KFR06011.1 - 0.02 14.4 0.9 0.032 13.7 0.9 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF4455 PF14643.6 KFR06011.1 - 0.021 13.5 0.5 0.034 12.8 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) DUF2730 PF10805.8 KFR06011.1 - 0.024 14.7 0.2 0.058 13.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Spc29 PF17082.5 KFR06011.1 - 0.025 14.4 0.1 0.044 13.6 0.1 1.4 1 0 0 1 1 1 0 Spindle Pole Component 29 Tropomyosin PF00261.20 KFR06011.1 - 0.036 13.4 1.7 0.056 12.8 1.7 1.2 1 0 0 1 1 1 0 Tropomyosin DUF1664 PF07889.12 KFR06011.1 - 0.056 13.5 2.4 0.16 12.0 2.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KFR06011.1 - 0.071 13.3 1.2 0.15 12.2 1.2 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ADIP PF11559.8 KFR06011.1 - 0.085 12.9 2.9 0.18 11.9 2.9 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding MATH PF00917.26 KFR06011.1 - 0.11 12.7 0.0 3.2 8.0 0.0 2.4 1 1 0 1 1 1 0 MATH domain AAA_13 PF13166.6 KFR06011.1 - 0.17 10.5 1.2 0.25 10.0 1.2 1.1 1 0 0 1 1 1 0 AAA domain BLOC1_2 PF10046.9 KFR06011.1 - 0.18 12.1 1.3 0.68 10.3 0.5 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_DNA_bd PF12329.8 KFR06011.1 - 0.23 11.5 2.1 0.45 10.5 2.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TACC_C PF05010.14 KFR06011.1 - 0.46 10.2 7.4 0.038 13.8 1.8 1.9 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Cortex-I_coil PF09304.10 KFR06011.1 - 0.47 10.7 4.4 0.28 11.4 0.9 2.3 3 0 0 3 3 2 0 Cortexillin I, coiled coil Csm1_N PF18504.1 KFR06011.1 - 0.88 10.0 3.1 7.4 7.0 0.5 2.4 1 1 1 2 2 2 0 Csm1 N-terminal domain PKcGMP_CC PF16808.5 KFR06011.1 - 1.2 9.0 4.2 4.4 7.3 0.9 2.7 1 1 2 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HbrB PF08539.11 KFR06012.1 - 6.5e-11 42.5 0.6 3.3e-08 33.7 0.1 2.5 1 1 1 2 2 2 2 HbrB-like COMM_domain PF07258.14 KFR06013.1 - 1.4e-25 89.2 0.0 2.9e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 COMM domain Ldl_recept_a PF00057.18 KFR06014.1 - 8.8e-34 115.4 42.8 6.6e-12 45.4 9.5 3.3 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A RCR PF12273.8 KFR06014.1 - 0.035 14.8 0.0 0.13 13.0 0.0 1.8 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red PspB PF06667.12 KFR06014.1 - 0.066 13.3 0.8 0.16 12.0 0.3 1.8 2 0 0 2 2 2 0 Phage shock protein B Trypsin PF00089.26 KFR06015.1 - 4e-37 128.2 0.0 5.8e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 KFR06015.1 - 1.6e-24 86.4 0.1 4.1e-24 85.0 0.0 1.8 2 0 0 2 2 2 1 CUB domain Sushi PF00084.20 KFR06015.1 - 3.3e-17 62.8 1.8 4.4e-08 33.6 0.2 3.2 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) EGF PF00008.27 KFR06015.1 - 9.5e-09 35.4 5.3 9.5e-09 35.4 5.3 3.7 4 0 0 4 4 4 1 EGF-like domain hEGF PF12661.7 KFR06015.1 - 0.00014 22.3 1.4 0.00014 22.3 1.4 4.1 2 0 0 2 2 2 1 Human growth factor-like EGF DUF1986 PF09342.11 KFR06015.1 - 0.0025 18.2 0.6 0.0087 16.4 0.6 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) EGF_2 PF07974.13 KFR06015.1 - 0.019 15.3 8.2 0.019 15.3 8.2 4.3 5 1 0 5 5 5 0 EGF-like domain DEAD PF00270.29 KFR06017.1 - 9.5e-44 149.2 0.3 1.7e-43 148.4 0.3 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFR06017.1 - 2.6e-32 111.5 0.5 8.5e-31 106.6 0.1 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFR06017.1 - 1.6e-07 31.5 0.0 2.8e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KFR06017.1 - 5.5e-05 23.5 0.3 0.00021 21.7 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFR06017.1 - 0.0011 18.7 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 KFR06017.1 - 0.071 13.1 0.0 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 KFR06017.1 - 0.072 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Helicase tRNA-synt_1b PF00579.25 KFR06017.1 - 0.081 12.2 0.1 0.25 10.6 0.0 1.8 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) AAA_22 PF13401.6 KFR06017.1 - 0.1 12.8 0.4 1.2 9.5 0.4 2.4 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 KFR06017.1 - 0.14 11.6 0.2 0.24 10.9 0.2 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Fanconi_A PF03511.14 KFR06017.1 - 0.16 11.9 0.0 27 4.8 0.0 2.4 2 0 0 2 2 2 0 Fanconi anaemia group A protein Rep_fac_C PF08542.11 KFR06018.1 - 9.3e-20 70.8 0.2 2e-19 69.8 0.2 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KFR06018.1 - 8.3e-18 65.1 0.0 3.1e-17 63.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KFR06018.1 - 2e-12 47.2 0.0 2e-10 40.7 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 KFR06018.1 - 2.9e-06 27.5 0.1 1.3e-05 25.4 0.0 2.1 1 1 1 2 2 2 1 AAA C-terminal domain AAA_16 PF13191.6 KFR06018.1 - 3.6e-06 27.5 0.1 0.0027 18.1 0.0 2.7 2 2 1 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 KFR06018.1 - 1.4e-05 24.9 0.0 4.5e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFR06018.1 - 6.4e-05 23.2 0.1 0.0047 17.2 0.0 2.8 2 2 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KFR06018.1 - 6.4e-05 22.9 0.2 0.00025 20.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KFR06018.1 - 0.00042 20.1 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 KFR06018.1 - 0.00099 18.9 0.6 0.0023 17.7 0.1 1.8 2 0 0 2 2 2 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 KFR06018.1 - 0.0014 18.0 0.0 0.038 13.4 0.0 2.7 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KFR06018.1 - 0.0014 18.9 0.1 0.01 16.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KFR06018.1 - 0.0042 16.3 0.0 0.0089 15.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KFR06018.1 - 0.0092 15.7 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 KFR06018.1 - 0.01 15.6 0.0 0.49 10.1 0.0 2.3 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 KFR06018.1 - 0.016 15.2 0.1 0.088 12.8 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49_C PF17856.1 KFR06018.1 - 0.018 15.1 0.1 0.054 13.6 0.1 1.8 1 0 0 1 1 1 0 TIP49 AAA-lid domain AAA_23 PF13476.6 KFR06018.1 - 0.034 14.7 0.0 0.072 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KFR06018.1 - 0.045 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KFR06018.1 - 0.047 13.1 0.1 5.4 6.4 0.0 2.7 3 0 0 3 3 3 0 PhoH-like protein DEAD PF00270.29 KFR06018.1 - 0.048 13.4 0.1 1.3 8.8 0.0 2.8 2 1 1 3 3 3 0 DEAD/DEAH box helicase AAA_28 PF13521.6 KFR06018.1 - 0.057 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 KFR06018.1 - 0.059 13.4 0.0 0.29 11.1 0.0 2.2 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 KFR06018.1 - 0.089 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RhoGEF PF00621.20 KFR06019.1 - 3.8e-38 131.5 6.5 3.8e-38 131.5 6.5 2.5 3 1 0 3 3 3 1 RhoGEF domain PH PF00169.29 KFR06019.1 - 5e-09 36.6 2.5 6.6e-09 36.2 1.1 2.0 2 0 0 2 2 2 1 PH domain CRAL_TRIO_2 PF13716.6 KFR06019.1 - 1.7e-06 28.3 0.0 4.5e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Spectrin PF00435.21 KFR06019.1 - 2.7e-05 24.6 1.3 2.7e-05 24.6 1.3 4.8 3 1 2 5 5 5 2 Spectrin repeat PH_10 PF15411.6 KFR06019.1 - 5.6e-05 23.4 0.6 5.6e-05 23.4 0.6 2.6 3 0 0 3 3 3 1 Pleckstrin homology domain CRAL_TRIO PF00650.20 KFR06019.1 - 0.089 12.5 0.0 0.27 11.0 0.0 1.8 1 0 0 1 1 1 0 CRAL/TRIO domain Goodbye PF17109.5 KFR06019.1 - 0.38 11.2 2.5 1.8 9.0 0.1 3.3 4 0 0 4 4 4 0 fungal STAND N-terminal Goodbye domain Galactosyl_T PF01762.21 KFR06020.1 - 3.6e-44 150.9 0.1 5.4e-44 150.4 0.1 1.3 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 KFR06020.1 - 0.00033 20.2 0.1 0.00071 19.1 0.1 1.6 1 1 0 1 1 1 1 Fringe-like EBP50_C PF09007.11 KFR06021.1 - 0.49 11.4 10.0 0.057 14.4 5.1 1.9 1 1 1 2 2 2 0 EBP50, C-terminal Lamp PF01299.17 KFR06022.1 - 2.6e-21 76.0 0.4 3.1e-21 75.8 0.4 1.1 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) bPH_1 PF08000.11 KFR06022.1 - 0.0067 16.5 0.0 0.0096 16.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial PH domain CPSase_L_D2 PF02786.17 KFR06023.1 - 6.5e-77 257.8 0.2 1.2e-76 256.9 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KFR06023.1 - 9.5e-49 164.5 1.9 1.6e-47 160.6 0.3 2.8 3 0 0 3 3 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KFR06023.1 - 2.9e-36 123.8 0.0 1.6e-35 121.5 0.0 2.3 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KFR06023.1 - 1.6e-15 56.7 0.6 6.8e-15 54.7 0.6 2.1 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KFR06023.1 - 7.4e-14 51.8 0.1 2.4e-13 50.1 0.1 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFR06023.1 - 7.7e-09 35.4 0.2 1.8e-08 34.1 0.2 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KFR06023.1 - 1.8e-05 24.8 0.1 3.4e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KFR06023.1 - 3.1e-05 23.7 0.0 0.00014 21.5 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.6 KFR06023.1 - 0.00019 22.1 0.2 0.49 11.1 0.0 2.9 2 0 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 KFR06023.1 - 0.00023 20.9 4.0 0.0082 16.0 0.0 3.2 4 0 0 4 4 4 1 Biotin-lipoyl like GARS_A PF01071.19 KFR06023.1 - 0.0014 18.4 0.0 0.0026 17.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 KFR06023.1 - 0.0017 17.6 0.7 0.33 10.2 0.0 2.9 3 0 0 3 3 3 1 Sugar-transfer associated ATP-grasp HlyD_D23 PF16576.5 KFR06023.1 - 0.0018 17.5 0.1 0.84 8.8 0.0 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion RnfC_N PF13375.6 KFR06023.1 - 0.039 13.9 0.4 0.14 12.1 0.4 1.9 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain NQRA PF05896.11 KFR06023.1 - 0.1 12.0 0.3 0.2 11.1 0.3 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) ATP-grasp_4 PF13535.6 KFR06023.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain Cullin_binding PF03556.15 KFR06024.1 - 1.4e-37 128.8 0.9 1.4e-37 128.8 0.9 2.1 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.6 KFR06024.1 - 1.1e-09 38.0 3.0 1.3e-09 37.7 0.1 2.7 3 0 0 3 3 3 1 UBA-like domain TAP_C PF03943.13 KFR06024.1 - 0.0038 16.8 0.8 0.024 14.3 0.2 2.6 3 0 0 3 3 3 1 TAP C-terminal domain PhoLip_ATPase_C PF16212.5 KFR06025.1 - 1.3e-77 261.0 37.3 1.3e-77 261.0 37.3 2.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFR06025.1 - 1.4e-22 79.2 1.8 9.5e-22 76.5 1.8 2.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFR06025.1 - 5.1e-13 49.8 1.3 1.7e-07 31.8 1.0 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFR06025.1 - 7.1e-10 38.8 0.0 5.6e-09 36.0 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFR06025.1 - 1.2e-09 38.0 0.5 1.2e-09 38.0 0.5 3.1 2 2 1 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFR06025.1 - 0.0002 21.2 0.0 0.0073 16.1 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFR06025.1 - 0.098 13.0 0.1 16 5.8 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase U3_assoc_6 PF08640.11 KFR06025.1 - 0.14 12.2 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 SOXp PF12336.8 KFR06026.1 - 1.7e-38 131.6 5.4 1.7e-38 131.6 5.4 2.0 3 0 0 3 3 3 1 SOX transcription factor HMG_box PF00505.19 KFR06026.1 - 5.2e-15 55.6 0.8 8.9e-15 54.9 0.8 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFR06026.1 - 1.3e-06 28.9 0.2 2.4e-06 28.0 0.2 1.5 1 0 0 1 1 1 1 HMG-box domain DnaJ PF00226.31 KFR06027.1 - 2.4e-08 34.0 0.0 4.8e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 KFR06027.1 - 0.00048 20.1 0.0 0.00049 20.1 0.0 1.2 1 0 0 1 1 1 1 Pam16 FXMRP1_C_core PF12235.8 KFR06028.1 - 7.5e-47 159.4 10.7 7.5e-47 159.4 10.7 3.6 1 1 2 3 3 3 1 Fragile X-related 1 protein core C terminal FXR_C1 PF16096.5 KFR06028.1 - 1.1e-38 131.2 12.0 1.1e-38 131.2 12.0 3.5 2 1 1 3 3 3 1 Fragile X-related 1 protein C-terminal region 2 KH_9 PF17904.1 KFR06028.1 - 9.1e-36 122.1 0.7 2.4e-35 120.8 0.7 1.8 1 0 0 1 1 1 1 FMRP KH0 domain FXR_C3 PF16097.5 KFR06028.1 - 1.4e-26 92.9 7.7 1.4e-26 92.9 7.7 3.1 3 1 1 4 4 4 1 Fragile X-related 1 protein C-terminal region 3 KH_1 PF00013.29 KFR06028.1 - 2.3e-17 62.6 1.0 1.5e-09 37.5 0.5 2.7 2 0 0 2 2 2 2 KH domain Agenet PF05641.12 KFR06028.1 - 2e-08 34.6 0.2 2e-08 34.6 0.2 2.7 3 0 0 3 3 3 1 Agenet domain Tudor_FRX1 PF18336.1 KFR06028.1 - 1.6e-05 24.7 3.9 1.6e-05 24.7 3.9 2.0 2 0 0 2 2 2 1 Fragile X mental retardation Tudor domain KH_2 PF07650.17 KFR06028.1 - 0.00024 20.8 0.8 0.15 11.9 0.0 2.6 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 KFR06028.1 - 0.36 10.7 4.9 2.1 8.3 0.4 3.5 3 1 1 4 4 4 0 KH domain Tombus_movement PF05318.12 KFR06028.1 - 7.3 7.5 7.0 0.84 10.5 0.2 2.8 2 1 0 2 2 2 0 Tombusvirus movement protein CENP-F_leu_zip PF10473.9 KFR06029.1 - 0.0018 18.3 21.3 0.0018 18.3 21.3 8.7 2 2 4 7 7 7 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 KFR06029.1 - 0.0048 17.0 18.2 0.0048 17.0 18.2 8.9 2 2 7 9 9 9 1 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KFR06029.1 - 0.051 12.4 158.5 0.19 10.6 22.2 7.4 2 2 5 7 7 7 0 Spc7 kinetochore protein TPR_1 PF00515.28 KFR06030.1 - 7.4e-13 47.7 0.2 0.0007 19.3 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFR06030.1 - 3.8e-12 45.3 3.9 0.0005 20.0 0.0 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFR06030.1 - 2.1e-10 40.1 0.6 6e-09 35.4 0.1 2.9 2 1 0 2 2 2 1 TPR repeat TPR_8 PF13181.6 KFR06030.1 - 3.8e-08 32.9 0.7 0.064 13.5 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFR06030.1 - 1.8e-07 31.4 0.1 0.038 14.8 0.0 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFR06030.1 - 1.7e-06 28.6 0.1 1.4e-05 25.6 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFR06030.1 - 3.8e-06 26.9 0.5 0.00035 20.7 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFR06030.1 - 7.2e-06 26.1 0.0 2.8e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFR06030.1 - 0.00057 20.1 1.9 0.96 9.8 0.6 3.3 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFR06030.1 - 0.002 18.6 3.6 0.022 15.3 0.1 3.4 1 1 3 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFR06030.1 - 0.0039 16.4 2.4 0.0078 15.5 2.4 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat S1 PF00575.23 KFR06030.1 - 0.004 17.4 0.0 0.14 12.5 0.0 2.5 1 1 0 1 1 1 1 S1 RNA binding domain HCNGP PF07818.13 KFR06030.1 - 0.024 15.3 2.3 0.073 13.7 0.0 2.5 2 0 0 2 2 2 0 HCNGP-like protein Herpes_pp85 PF04637.12 KFR06030.1 - 0.061 11.7 5.6 0.1 11.0 5.6 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Mem_trans PF03547.18 KFR06030.1 - 9.5 4.5 8.5 19 3.5 8.5 1.5 1 0 0 1 1 1 0 Membrane transport protein TPR_1 PF00515.28 KFR06031.1 - 2.3e-26 90.5 1.0 2e-05 24.2 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFR06031.1 - 5.1e-22 76.2 5.6 0.00021 21.2 0.0 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KFR06031.1 - 1.2e-19 68.8 0.3 0.0023 18.0 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFR06031.1 - 6e-15 54.6 1.0 0.0015 18.1 0.0 5.5 3 2 2 5 5 5 3 TPR repeat TPR_14 PF13428.6 KFR06031.1 - 1.5e-14 53.5 6.5 0.0037 18.0 0.7 6.5 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 KFR06031.1 - 4.3e-14 52.8 5.0 0.00037 21.0 1.9 4.7 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 KFR06031.1 - 1.1e-13 50.5 9.1 0.0052 17.1 0.5 5.6 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 KFR06031.1 - 1.5e-11 44.3 2.1 0.00026 21.1 0.4 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFR06031.1 - 3.6e-11 43.5 6.9 6.7e-06 26.6 0.4 4.5 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_20 PF14561.6 KFR06031.1 - 8.4e-09 35.6 4.0 0.00025 21.3 0.7 4.6 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFR06031.1 - 1.7e-08 33.9 2.8 2.2 8.5 0.1 6.2 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFR06031.1 - 2.4e-08 34.2 6.2 0.78 10.1 0.0 4.7 2 2 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFR06031.1 - 6.4e-08 32.7 1.4 0.0015 18.7 1.1 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KFR06031.1 - 4.6e-07 30.0 4.8 6.3 7.7 0.2 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_3 PF07720.12 KFR06031.1 - 0.0055 16.7 0.0 5 7.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 KFR06031.1 - 0.0056 16.1 5.2 7.6 6.1 0.1 3.6 3 0 0 3 3 3 1 SHNi-TPR TPR_15 PF13429.6 KFR06031.1 - 0.0096 15.2 4.4 0.07 12.3 0.8 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4248 PF14053.6 KFR06031.1 - 0.012 15.6 0.2 0.034 14.2 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) DUF4919 PF16266.5 KFR06031.1 - 0.034 14.1 0.2 0.086 12.8 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) BTAD PF03704.17 KFR06031.1 - 0.046 14.2 5.4 8 6.9 0.1 4.0 4 0 0 4 4 4 0 Bacterial transcriptional activator domain Wzy_C_2 PF11846.8 KFR06031.1 - 0.11 12.4 0.4 0.26 11.2 0.4 1.6 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal DUF5105 PF17118.5 KFR06031.1 - 0.12 12.1 3.1 0.23 11.2 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5105) DUF4192 PF13830.6 KFR06031.1 - 1.6 8.7 5.1 0.91 9.5 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4192) UCH PF00443.29 KFR06032.1 - 5.7e-48 163.6 0.0 7.7e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 KFR06032.1 - 7.6e-25 86.4 0.5 2.3e-12 46.5 0.1 3.2 3 0 0 3 3 3 2 UBA/TS-N domain zf-UBP PF02148.19 KFR06032.1 - 6.6e-17 61.6 1.1 1.2e-14 54.4 0.0 2.8 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 KFR06032.1 - 5.1e-14 51.8 0.6 1.2e-12 47.4 0.3 2.6 2 0 0 2 2 2 1 Variant UBP zinc finger UCH_1 PF13423.6 KFR06032.1 - 8.3e-12 45.3 0.1 0.00033 20.4 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 KFR06032.1 - 0.011 15.6 0.1 0.024 14.5 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain UBA_3 PF09288.10 KFR06032.1 - 0.084 12.7 0.3 1.5 8.7 0.0 2.8 3 0 0 3 3 3 0 Fungal ubiquitin-associated domain NDUF_B5 PF09781.9 KFR06033.1 - 6.6e-80 267.1 0.7 7.3e-80 267.0 0.7 1.0 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit MRP-L47 PF06984.13 KFR06034.1 - 7.5e-36 122.1 1.4 1.4e-35 121.3 1.4 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Actin PF00022.19 KFR06035.1 - 3.3e-120 401.5 0.0 1.7e-98 329.9 0.0 2.0 1 1 1 2 2 2 2 Actin MobA_MobL PF03389.15 KFR06035.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 MobA/MobL family WD40 PF00400.32 KFR06036.1 - 2e-44 148.7 21.2 4.1e-08 33.8 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR06036.1 - 2.4e-16 59.8 0.0 0.00086 19.6 0.0 5.7 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFR06036.1 - 8.4e-05 22.5 0.0 0.42 10.5 0.0 2.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KFR06036.1 - 0.00011 21.7 0.0 0.024 14.0 0.0 2.9 1 1 1 2 2 2 2 WD40-like domain Fzo_mitofusin PF04799.13 KFR06037.1 - 1.4e-72 242.5 5.8 1.4e-72 242.5 5.8 3.2 2 1 1 3 3 3 1 fzo-like conserved region Dynamin_N PF00350.23 KFR06037.1 - 1.8e-23 83.5 0.0 1.8e-23 83.5 0.0 3.7 3 1 0 4 4 4 1 Dynamin family MMR_HSR1 PF01926.23 KFR06037.1 - 4.2e-08 33.3 0.1 3.5e-07 30.3 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 KFR06037.1 - 0.068 13.4 0.2 14 6.0 0.0 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Apolipoprotein PF01442.18 KFR06037.1 - 0.18 11.6 11.9 0.21 11.5 1.8 2.7 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain AAA_23 PF13476.6 KFR06037.1 - 0.22 12.0 16.0 7.1 7.1 0.0 3.5 3 0 0 3 3 3 0 AAA domain CorA PF01544.18 KFR06037.1 - 0.54 9.5 7.7 0.41 9.9 0.9 2.8 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Phospholip_A2_3 PF09056.11 KFR06037.1 - 1.7 9.3 4.6 1.5 9.5 0.1 3.0 4 0 0 4 4 3 0 Prokaryotic phospholipase A2 Tup_N PF08581.10 KFR06037.1 - 2.9 8.3 11.5 4.5 7.6 0.3 3.8 3 1 0 3 3 3 0 Tup N-terminal GrpE PF01025.19 KFR06037.1 - 3.9 7.1 13.9 7.1 6.3 3.6 2.9 2 0 0 2 2 2 0 GrpE TMF_TATA_bd PF12325.8 KFR06037.1 - 4 7.7 14.4 0.32 11.2 4.3 3.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Baculo_PEP_C PF04513.12 KFR06037.1 - 5.7 7.0 9.9 3.4 7.7 1.7 2.9 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 KFR06037.1 - 8.7 6.8 9.4 42 4.6 0.2 3.8 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels zf-C2H2 PF00096.26 KFR06038.1 - 3e-16 58.8 59.3 0.0025 18.2 1.0 9.6 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR06038.1 - 7.8e-14 51.2 60.4 0.0051 17.6 1.3 9.8 9 0 0 9 9 9 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFR06038.1 - 1.8e-11 43.9 49.0 0.00017 21.8 0.2 9.7 9 0 0 9 9 9 5 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFR06038.1 - 2.2e-11 43.3 42.8 5.5e-05 22.8 2.3 7.7 8 0 0 8 8 8 3 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFR06038.1 - 0.0017 18.3 1.3 0.0017 18.3 1.3 8.3 8 1 0 8 8 8 1 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KFR06038.1 - 0.002 17.7 44.1 0.021 14.5 0.2 6.9 5 3 1 6 6 6 3 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 KFR06038.1 - 0.06 13.7 1.0 0.06 13.7 1.0 7.4 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFR06038.1 - 0.16 12.3 31.0 0.17 12.2 2.4 5.1 1 1 3 5 5 5 0 C2H2-type zinc ribbon zinc_ribbon_15 PF17032.5 KFR06038.1 - 0.23 12.2 33.9 0.19 12.5 3.5 5.0 3 1 2 5 5 5 0 zinc-ribbon family CarbpepA_inh PF02977.15 KFR06038.1 - 1.4 8.7 14.7 1.9 8.4 0.0 5.1 5 0 0 5 5 5 0 Carboxypeptidase A inhibitor zf-C2H2_2 PF12756.7 KFR06038.1 - 9.7 6.6 49.0 4.7 7.6 4.8 5.7 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) PI3Ka PF00613.20 KFR06039.1 - 9.7e-70 233.7 1.9 1.9e-69 232.8 1.9 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KFR06039.1 - 7.2e-57 193.1 1.9 4.4e-56 190.5 1.9 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_rbd PF00794.18 KFR06039.1 - 4.6e-39 132.9 1.4 3e-37 127.0 0.7 2.9 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 KFR06039.1 - 5.8e-33 113.8 0.0 1.1e-32 112.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_p85B PF02192.16 KFR06039.1 - 8.6e-31 105.5 0.4 2.3e-30 104.2 0.4 1.8 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain DUF2321 PF10083.9 KFR06039.1 - 0.018 14.7 0.0 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) DUF4135 PF13575.6 KFR06039.1 - 0.062 12.6 0.0 0.16 11.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) zf-met PF12874.7 KFR06040.1 - 1.9e-22 78.9 16.9 1.4e-08 34.8 0.4 3.4 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFR06040.1 - 9e-20 70.5 16.7 9.2e-07 29.0 0.2 3.3 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFR06040.1 - 3.3e-09 37.0 11.5 0.016 15.5 0.5 3.2 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFR06040.1 - 0.00034 21.2 5.8 2.5 9.2 0.1 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-U1 PF06220.12 KFR06040.1 - 0.00088 19.0 18.3 0.1 12.4 3.0 3.6 3 1 0 3 3 3 2 U1 zinc finger AKAP95 PF04988.12 KFR06040.1 - 0.01 16.1 0.7 0.01 16.1 0.7 3.0 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) CaKB PF03185.15 KFR06041.1 - 2.8e-84 281.7 9.0 3.2e-84 281.5 9.0 1.0 1 0 0 1 1 1 1 Calcium-activated potassium channel, beta subunit KcnmB2_inactiv PF09303.10 KFR06041.1 - 3e-06 26.9 2.0 3e-06 26.9 2.0 1.6 2 0 0 2 2 2 1 KCNMB2, ball and chain domain AAA_8 PF12780.7 KFR06041.1 - 0.0026 17.1 0.0 0.0033 16.8 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 tRNA-synt_1g PF09334.11 KFR06041.1 - 0.019 13.7 0.0 0.027 13.2 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) WD40 PF00400.32 KFR06042.1 - 3.1e-52 173.4 25.5 3.4e-10 40.3 0.2 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR06042.1 - 5.2e-29 100.4 1.7 6.9e-08 32.7 0.1 6.1 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFR06042.1 - 1.5e-11 44.5 0.5 0.0011 18.9 0.1 3.4 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 KFR06042.1 - 5.9e-10 38.7 0.1 3.7e-09 36.2 0.0 2.2 2 0 0 2 2 2 1 LisH WD40_like PF17005.5 KFR06042.1 - 4.4e-05 23.0 0.0 0.08 12.3 0.0 3.0 3 1 0 3 3 3 2 WD40-like domain Coatomer_WDAD PF04053.14 KFR06042.1 - 0.00015 21.0 0.0 0.0045 16.1 0.0 2.4 2 0 0 2 2 2 1 Coatomer WD associated region Ge1_WD40 PF16529.5 KFR06042.1 - 0.00017 20.6 1.2 0.96 8.3 0.0 3.4 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFR06042.1 - 0.0051 15.5 4.6 0.45 9.1 0.0 3.7 2 2 2 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.12 KFR06042.1 - 0.031 14.2 0.0 0.49 10.4 0.0 3.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Glyco_hydro_11 PF00457.17 KFR06042.1 - 0.052 13.2 1.1 1.7 8.2 0.1 2.7 2 0 0 2 2 2 0 Glycosyl hydrolases family 11 K_channel_TID PF07941.11 KFR06042.1 - 0.1 13.0 6.1 0.2 12.1 6.1 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain PCuAC PF04314.13 KFR06042.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Copper chaperone PCu(A)C IKI3 PF04762.12 KFR06042.1 - 0.21 9.6 0.3 4.7 5.1 0.1 2.5 2 1 1 3 3 3 0 IKI3 family Peptidase_M28 PF04389.17 KFR06043.1 - 1.9e-06 27.7 0.0 1.3e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M28 TFR_dimer PF04253.15 KFR06043.1 - 4e-06 26.9 0.0 6.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain CTF_NFI PF00859.18 KFR06072.1 - 2.1e-145 484.2 25.3 2.4e-145 484.0 25.3 1.0 1 0 0 1 1 1 1 CTF/NF-I family transcription modulation region HEAT_2 PF13646.6 KFR06073.1 - 2.9e-21 75.6 0.2 1.9e-14 53.8 0.0 2.0 1 1 1 2 2 2 2 HEAT repeats HEAT_PBS PF03130.16 KFR06073.1 - 2.1e-14 52.6 0.7 3.7e-05 24.0 0.0 3.3 3 0 0 3 3 3 3 PBS lyase HEAT-like repeat HEAT PF02985.22 KFR06073.1 - 0.0029 17.7 0.1 0.11 12.9 0.0 3.0 4 0 0 4 4 4 1 HEAT repeat DDE_Tnp_4 PF13359.6 KFR06074.1 - 2.6e-28 98.7 0.0 3.7e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFR06074.1 - 6.5e-12 45.5 0.0 9.1e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein HTH_Tnp_4 PF13613.6 KFR06074.1 - 4.6e-05 23.1 0.0 9.3e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KFR06074.1 - 0.0048 16.6 0.1 0.03 13.9 0.1 2.0 1 1 0 1 1 1 1 Transposase DDE domain HMG_box PF00505.19 KFR06076.1 - 6.4e-20 71.3 1.1 6.4e-20 71.3 1.1 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFR06076.1 - 8.2e-12 45.5 0.4 8.2e-12 45.5 0.4 2.1 3 0 0 3 3 3 1 HMG-box domain LMBR1 PF04791.16 KFR06076.1 - 0.015 14.3 2.7 0.017 14.0 2.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF724 PF05266.14 KFR06076.1 - 0.026 14.3 8.3 0.035 13.9 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Caldesmon PF02029.15 KFR06076.1 - 0.035 12.9 10.0 0.042 12.6 10.0 1.1 1 0 0 1 1 1 0 Caldesmon APG6_N PF17675.1 KFR06076.1 - 0.065 13.8 23.6 1.1 9.8 24.1 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF812 PF05667.11 KFR06076.1 - 0.083 11.8 14.0 0.13 11.1 14.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Leu_zip PF15294.6 KFR06076.1 - 0.48 9.9 14.0 0.06 12.9 6.2 2.1 2 0 0 2 2 2 0 Leucine zipper PI3K_P85_iSH2 PF16454.5 KFR06076.1 - 3.7 7.1 27.0 12 5.4 27.0 1.8 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain PDZ PF00595.24 KFR06077.1 - 5.3e-07 29.9 0.0 8.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PIP5K PF01504.18 KFR06079.1 - 6.9e-94 314.1 0.0 8.6e-94 313.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Toxin_33 PF08121.11 KFR06079.1 - 0.2 11.5 0.8 0.39 10.6 0.8 1.5 1 0 0 1 1 1 0 Waglerin family PDZ PF00595.24 KFR06080.1 - 9.9e-44 147.6 4.0 7.7e-15 55.0 0.1 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 KFR06080.1 - 5.5e-27 93.4 0.1 1.4e-10 40.8 0.0 3.7 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 KFR06080.1 - 9.5e-19 67.5 0.3 1.6e-07 31.5 0.0 3.5 3 0 0 3 3 3 3 PDZ domain SH3_2 PF07653.17 KFR06080.1 - 4.2e-11 42.3 0.0 3.2e-10 39.5 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain Guanylate_kin PF00625.21 KFR06080.1 - 4e-10 39.7 0.0 1.9e-09 37.5 0.0 1.9 1 1 1 2 2 2 1 Guanylate kinase Tricorn_PDZ PF14685.6 KFR06080.1 - 3.4e-05 23.7 0.1 0.12 12.4 0.0 2.8 2 0 0 2 2 2 2 Tricorn protease PDZ domain SH3_1 PF00018.28 KFR06080.1 - 0.0021 17.6 0.0 0.0052 16.4 0.0 1.7 1 0 0 1 1 1 1 SH3 domain PID PF00640.23 KFR06081.1 - 2.4e-44 150.8 0.1 3.8e-44 150.1 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.24 KFR06081.1 - 1e-28 99.5 4.2 1.1e-14 54.6 0.1 2.5 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 KFR06081.1 - 5.2e-16 58.2 1.1 1.6e-07 31.0 0.1 2.8 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 KFR06081.1 - 3.2e-06 27.4 0.0 0.00048 20.4 0.0 2.4 2 0 0 2 2 2 1 PDZ domain DUF993 PF06187.11 KFR06081.1 - 0.002 17.1 0.2 0.003 16.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF993) NRho PF16733.5 KFR06081.1 - 0.03 14.4 0.4 0.11 12.6 0.1 1.9 2 0 0 2 2 2 0 Rhomboid N-terminal domain Ribosomal_L37 PF08561.10 KFR06082.1 - 1.9e-09 38.1 0.4 2.3e-09 37.8 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 Peptidase_C14 PF00656.22 KFR06083.1 - 3.9e-18 66.3 0.0 3.9e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Homeodomain PF00046.29 KFR06084.1 - 1.9e-24 85.2 4.7 3e-24 84.6 4.7 1.3 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 KFR06084.1 - 2e-10 40.2 1.4 4.3e-10 39.1 1.4 1.6 1 0 0 1 1 1 1 OAR domain T6SS_TssF PF05947.12 KFR06084.1 - 0.0036 15.9 0.0 0.0041 15.7 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF Homeobox_KN PF05920.11 KFR06084.1 - 0.052 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Homeobox KN domain Pkinase_Tyr PF07714.17 KFR06085.1 - 5e-88 294.7 0.0 6.5e-88 294.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR06085.1 - 3.5e-47 161.0 0.0 5.7e-47 160.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFR06085.1 - 6.1e-20 71.1 0.0 1.3e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFR06085.1 - 1.3e-08 34.3 0.0 2.6e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain APH PF01636.23 KFR06085.1 - 4.3e-05 23.6 0.0 0.00039 20.4 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family SH3_9 PF14604.6 KFR06085.1 - 0.0001 22.1 0.0 0.0003 20.6 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFR06085.1 - 0.00022 20.8 0.0 0.00049 19.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Kinase-like PF14531.6 KFR06085.1 - 0.015 14.6 0.0 0.031 13.6 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 KFR06085.1 - 0.028 13.4 0.0 0.044 12.7 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KFR06085.1 - 0.041 13.5 0.1 0.08 12.5 0.1 1.5 1 0 0 1 1 1 0 RIO1 family SH3_3 PF08239.11 KFR06085.1 - 0.077 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain Pkinase_fungal PF17667.1 KFR06085.1 - 0.088 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RRM_1 PF00076.22 KFR06086.1 - 1.9e-62 207.0 0.1 1.3e-19 69.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFR06086.1 - 2.5e-11 43.2 0.0 0.0014 18.2 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KFR06086.1 - 1.2e-05 25.4 0.0 0.04 14.1 0.0 2.9 3 0 0 3 3 3 2 BRCA1-associated protein 2 RRM_3 PF08777.11 KFR06086.1 - 0.00042 20.3 0.0 0.17 11.9 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif RRM_occluded PF16842.5 KFR06086.1 - 0.0022 17.8 0.0 1.2 9.0 0.0 2.9 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 KFR06086.1 - 0.0042 17.2 0.0 1.5 9.0 0.0 3.3 3 0 0 3 3 3 1 RNA recognition motif E2 PF08199.11 KFR06086.1 - 0.1 12.5 0.0 0.35 10.8 0.0 1.9 1 0 0 1 1 1 0 Bacteriophage E2-like protein SET_assoc PF11767.8 KFR06086.1 - 0.12 12.1 0.0 5.9 6.6 0.0 2.6 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated SDF PF00375.18 KFR06087.1 - 1.5e-125 419.3 25.1 1.7e-125 419.1 25.1 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family hSH3 PF14603.6 KFR06088.1 - 9.7e-27 93.2 0.0 1.1e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Helically-extended SH3 domain SH3_2 PF07653.17 KFR06088.1 - 0.00026 20.6 0.0 0.00035 20.2 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFR06088.1 - 0.037 13.9 0.0 0.053 13.4 0.0 1.2 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.28 KFR06088.1 - 0.054 13.1 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 SH3 domain DUF2890 PF11081.8 KFR06089.1 - 0.019 15.1 2.6 0.022 14.9 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) TGF_beta PF00019.20 KFR06090.1 - 1.4e-31 109.6 0.1 2e-31 109.0 0.1 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFR06090.1 - 6.6e-25 88.3 0.0 9.3e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TIP39 PF14980.6 KFR06091.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 TIP39 peptide Ribosomal_S28e PF01200.18 KFR06092.1 - 2.9e-31 107.3 1.1 3.1e-31 107.1 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Ank_4 PF13637.6 KFR06093.1 - 3.7e-27 94.3 7.7 6.1e-11 42.6 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFR06093.1 - 5.6e-27 94.1 8.8 1.7e-10 41.3 0.6 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFR06093.1 - 2.6e-24 84.6 6.4 1.3e-06 28.6 0.0 4.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KFR06093.1 - 2.3e-23 81.9 12.4 3.2e-10 40.0 0.2 4.8 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFR06093.1 - 6e-20 69.2 5.6 2.4e-05 24.4 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat DUF1870 PF08965.10 KFR06093.1 - 0.097 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) Nop14 PF04147.12 KFR06093.1 - 0.14 10.3 6.1 0.18 10.0 6.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KFR06093.1 - 0.44 8.8 3.6 0.6 8.3 3.6 1.2 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 KFR06093.1 - 2.3 7.5 11.7 4.8 6.5 11.7 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Fibrinogen_C PF00147.18 KFR06094.1 - 1.3e-61 208.2 0.2 1.3e-61 208.2 0.2 1.4 2 0 0 2 2 2 1 Fibrinogen beta and gamma chains, C-terminal globular domain UPF0242 PF06785.11 KFR06094.1 - 0.11 12.6 6.6 0.19 11.8 6.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 KFR06094.1 - 0.24 11.2 5.8 0.43 10.4 5.8 1.3 1 0 0 1 1 1 0 Septum formation initiator Ras PF00071.22 KFR06095.1 - 3.6e-63 212.0 0.1 4.3e-63 211.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR06095.1 - 8.4e-35 119.6 0.1 1.4e-34 118.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR06095.1 - 2.6e-12 46.6 0.1 3.3e-12 46.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFR06095.1 - 3.3e-07 30.4 0.1 5.5e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KFR06095.1 - 3.4e-05 24.1 0.1 0.00046 20.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KFR06095.1 - 6e-05 23.0 0.3 0.023 14.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFR06095.1 - 8.8e-05 22.1 0.1 0.00023 20.7 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFR06095.1 - 0.0065 16.9 0.1 0.011 16.1 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 KFR06095.1 - 0.0082 15.5 0.1 0.015 14.6 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.6 KFR06095.1 - 0.021 14.8 0.1 0.064 13.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 KFR06095.1 - 0.022 14.2 0.0 0.051 13.0 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KFR06095.1 - 0.03 14.8 0.4 0.051 14.1 0.4 1.8 1 1 0 1 1 1 0 ABC transporter FAD-SLDH PF12318.8 KFR06095.1 - 0.046 13.8 0.2 0.2 11.7 0.1 1.9 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase FeoB_N PF02421.18 KFR06095.1 - 0.049 13.2 0.1 0.16 11.5 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 KFR06095.1 - 0.075 12.4 0.1 0.24 10.8 0.1 2.1 1 1 0 1 1 1 0 Bacterial TniB protein PduV-EutP PF10662.9 KFR06095.1 - 0.087 12.6 0.0 0.25 11.1 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 KFR06095.1 - 0.15 11.9 1.6 0.28 10.9 0.5 1.9 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RINGv PF12906.7 KFR06096.1 - 3e-15 56.0 7.1 3e-15 56.0 7.1 2.8 4 0 0 4 4 4 1 RING-variant domain Vpu PF00558.19 KFR06096.1 - 0.011 15.5 0.3 0.021 14.6 0.3 1.3 1 0 0 1 1 1 0 Vpu protein zf-RING_2 PF13639.6 KFR06096.1 - 0.017 15.5 6.4 0.017 15.5 6.4 2.5 3 0 0 3 3 3 0 Ring finger domain zf-ANAPC11 PF12861.7 KFR06096.1 - 0.046 13.8 0.9 0.046 13.8 0.9 2.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger Inhibitor_Mig-6 PF11555.8 KFR06096.1 - 0.21 11.7 0.5 1 9.5 0.2 2.1 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 FANCL_C PF11793.8 KFR06096.1 - 0.25 11.5 5.7 0.47 10.7 2.3 2.8 2 1 1 3 3 3 0 FANCL C-terminal domain PRY PF13765.6 KFR06097.1 - 7.8e-23 79.9 0.0 1.2e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.28 KFR06097.1 - 1.3e-09 38.2 0.0 1.8e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 SPRY domain Opiods_neuropep PF01160.18 KFR06097.1 - 0.03 14.4 0.2 0.055 13.6 0.2 1.3 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide Peptidase_M42 PF05343.14 KFR06097.1 - 0.21 10.6 0.0 0.27 10.2 0.0 1.1 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase Herpes_IR6 PF06307.12 KFR06097.1 - 0.21 11.1 0.1 0.29 10.7 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus IR6 protein PRY PF13765.6 KFR06098.1 - 1.4e-20 72.6 0.0 2.3e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.28 KFR06098.1 - 1.7e-08 34.6 0.0 2e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 SPRY domain V-set PF07686.17 KFR06099.1 - 1.3e-06 28.5 0.0 1.3e-06 28.5 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFR06099.1 - 0.0021 18.2 0.0 0.0024 18.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFR06099.1 - 0.0083 16.7 0.0 0.0088 16.6 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFR06099.1 - 0.018 15.4 0.0 0.02 15.2 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain ASH PF15780.5 KFR06099.1 - 0.096 12.9 0.1 0.11 12.7 0.1 1.1 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin GATA PF00320.27 KFR06131.1 - 1.2e-29 101.6 19.4 8.5e-15 54.1 5.2 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KFR06131.1 - 1.1e-05 24.9 7.9 0.018 14.6 0.7 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding DUF2387 PF09526.10 KFR06131.1 - 0.0058 16.8 5.2 1.7 8.9 0.5 3.3 1 1 2 3 3 3 1 Probable metal-binding protein (DUF2387) ArfGap PF01412.18 KFR06131.1 - 0.028 14.5 8.2 0.078 13.1 0.4 2.5 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf Auto_anti-p27 PF06677.12 KFR06131.1 - 0.049 13.8 5.2 0.93 9.7 0.4 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.10 KFR06131.1 - 0.055 13.6 4.9 2 8.6 0.1 2.9 3 1 0 3 3 2 0 Zinc ribbon domain TDP43_N PF18694.1 KFR06131.1 - 0.19 11.6 0.2 5.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain Prim_Zn_Ribbon PF08273.12 KFR06131.1 - 0.28 11.5 9.4 0.28 11.5 2.1 2.7 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DZR PF12773.7 KFR06131.1 - 0.59 10.2 12.3 3.6 7.7 1.8 3.1 1 1 2 3 3 3 0 Double zinc ribbon Elf1 PF05129.13 KFR06131.1 - 3 8.0 7.8 8.6 6.5 0.3 2.7 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.11 KFR06131.1 - 3.9 7.5 13.1 5.7 6.9 2.7 3.1 3 0 0 3 3 3 0 Putative transposase DNA-binding domain eIF-5_eIF-2B PF01873.17 KFR06131.1 - 4.3 7.3 8.9 12 5.8 1.2 2.8 3 0 0 3 3 3 0 Domain found in IF2B/IF5 Vps36-NZF-N PF16988.5 KFR06131.1 - 5 6.6 8.7 0.99 8.8 0.4 3.0 2 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Sushi PF00084.20 KFR06144.1 - 1.2e-33 115.5 22.4 1.9e-08 34.7 0.2 4.3 4 0 0 4 4 4 4 Sushi repeat (SCR repeat) cEGF PF12662.7 KFR06144.1 - 0.0051 16.7 14.2 5.3 7.1 0.1 5.4 5 0 0 5 5 5 3 Complement Clr-like EGF-like HRM PF02793.22 KFR06144.1 - 0.55 10.6 7.3 1.8 8.9 0.4 3.9 3 1 0 3 3 3 0 Hormone receptor domain Patched PF02460.18 KFR06145.1 - 1.7e-21 76.1 27.5 2.5e-14 52.3 8.1 2.5 2 0 0 2 2 2 2 Patched family MMPL PF03176.15 KFR06145.1 - 2.6e-14 52.9 21.6 1.2e-08 34.3 7.4 2.3 2 0 0 2 2 2 2 MMPL family Sterol-sensing PF12349.8 KFR06145.1 - 4.5e-11 42.8 13.2 4.5e-11 42.8 13.2 2.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation BRO1 PF03097.18 KFR06146.1 - 4.8e-40 137.5 0.5 5.9e-40 137.3 0.5 1.0 1 0 0 1 1 1 1 BRO1-like domain Aida_C2 PF14186.6 KFR06147.1 - 5e-65 217.6 0.3 6.7e-65 217.2 0.3 1.2 1 0 0 1 1 1 1 Cytoskeletal adhesion Aida_N PF08910.10 KFR06147.1 - 8.3e-23 80.7 1.2 1.5e-22 79.9 1.2 1.4 1 0 0 1 1 1 1 Aida N-terminus NPIP PF06409.11 KFR06148.1 - 2e-12 46.8 9.2 1e-07 31.3 8.5 3.5 4 0 0 4 4 4 2 Nuclear pore complex interacting protein (NPIP) SH3_2 PF07653.17 KFR06148.1 - 1e-07 31.5 0.0 2.6e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF508 PF04370.12 KFR06148.1 - 0.048 13.4 5.5 0.1 12.3 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF508) TAF1_subA PF14929.6 KFR06149.1 - 3e-127 425.1 15.4 3.4e-127 424.9 15.4 1.0 1 0 0 1 1 1 1 TAF RNA Polymerase I subunit A DUF4363 PF14276.6 KFR06149.1 - 1.7 8.8 5.6 49 4.1 1.9 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4363) TPR_8 PF13181.6 KFR06149.1 - 2.4 8.6 4.2 12 6.4 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat GSDH PF07995.11 KFR06150.1 - 4.6e-38 131.4 0.0 7.8e-38 130.6 0.0 1.3 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Folate_rec PF03024.14 KFR06150.1 - 9e-10 38.7 11.4 1.5e-09 37.9 11.4 1.4 1 0 0 1 1 1 1 Folate receptor family DSPc PF00782.20 KFR06151.1 - 4.5e-42 143.0 0.6 1.1e-41 141.8 0.1 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 KFR06151.1 - 1e-14 54.9 0.0 3e-13 50.2 0.0 2.4 2 0 0 2 2 2 1 Rhodanese-like domain PTPlike_phytase PF14566.6 KFR06151.1 - 7.2e-06 26.2 0.0 1.6e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KFR06151.1 - 8.6e-05 22.2 0.1 0.0023 17.6 0.0 2.2 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KFR06151.1 - 0.0019 18.5 0.5 0.017 15.4 0.0 2.6 3 0 0 3 3 3 1 Rit1 DUSP-like domain AAA_18 PF13238.6 KFR06151.1 - 0.12 12.9 0.0 7.2 7.2 0.0 2.4 1 1 1 2 2 2 0 AAA domain MOSC_N PF03476.16 KFR06152.1 - 2e-36 124.5 0.0 3.3e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 KFR06152.1 - 1.4e-33 115.7 0.0 2e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 MOSC domain Pkinase PF00069.25 KFR06153.1 - 7e-76 255.1 0.0 1e-75 254.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR06153.1 - 5.6e-44 150.4 0.0 8.3e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KFR06153.1 - 9.4e-21 73.3 0.0 1.7e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 KFR06153.1 - 4.3e-07 29.5 0.0 9.8e-07 28.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like UBA PF00627.31 KFR06153.1 - 8.6e-07 28.7 0.0 1.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RIO1 PF01163.22 KFR06153.1 - 0.00056 19.6 0.2 0.0011 18.6 0.2 1.4 1 0 0 1 1 1 1 RIO1 family UBA_2 PF08587.11 KFR06153.1 - 0.0034 17.5 0.1 0.0089 16.1 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kdo PF06293.14 KFR06153.1 - 0.0074 15.7 0.1 0.015 14.7 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFR06153.1 - 0.069 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KFR06153.1 - 0.074 13.0 0.1 0.26 11.2 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family RAB3GAP2_C PF14656.6 KFR06154.1 - 1.1e-232 773.6 18.3 1.6e-232 773.0 18.3 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit C-terminus RAB3GAP2_N PF14655.6 KFR06154.1 - 2.9e-166 553.8 0.0 4.5e-166 553.2 0.0 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus SRP54_N PF02881.19 KFR06154.1 - 0.28 11.4 6.7 1 9.6 0.0 4.6 4 1 1 5 5 5 0 SRP54-type protein, helical bundle domain tRNA-synt_1 PF00133.22 KFR06155.1 - 6.7e-166 553.1 0.3 1.1e-165 552.3 0.1 1.3 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KFR06155.1 - 9.6e-27 93.8 0.0 2.4e-26 92.5 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KFR06155.1 - 4e-24 85.1 4.7 2.6e-16 59.4 0.0 3.6 4 0 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KFR06155.1 - 5e-05 22.9 0.0 8.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KFR06155.1 - 9.7e-05 21.9 0.0 0.038 13.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Inositol_P PF00459.25 KFR06156.1 - 2.6e-59 201.0 0.8 3.4e-59 200.6 0.8 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family tRNA-synt_1c PF00749.21 KFR06157.1 - 9.4e-123 409.1 0.6 1.9e-122 408.1 0.6 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain WHEP-TRS PF00458.20 KFR06157.1 - 3.3e-94 308.9 36.6 5.2e-24 84.2 4.0 5.1 4 0 0 4 4 4 4 WHEP-TRS domain tRNA-synt_1c_C PF03950.18 KFR06157.1 - 4.9e-37 127.5 0.0 1.4e-36 126.0 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain HGTP_anticodon PF03129.20 KFR06157.1 - 4.1e-18 65.3 0.5 6.1e-17 61.6 0.0 3.1 3 0 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KFR06157.1 - 1.8e-17 63.9 0.1 2.8e-16 60.0 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.11 KFR06157.1 - 1.5e-09 38.0 0.1 4.9e-09 36.3 0.1 1.9 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal GST_C PF00043.25 KFR06157.1 - 0.00053 20.1 2.0 0.0014 18.8 0.0 2.9 2 0 0 2 2 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFR06157.1 - 0.00082 19.5 2.1 0.0077 16.4 0.0 3.6 3 1 1 4 4 4 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 KFR06157.1 - 0.012 14.9 0.7 0.032 13.6 0.7 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain GST_C_2 PF13410.6 KFR06157.1 - 0.04 13.9 0.0 0.16 12.0 0.0 2.0 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ELFV_dehydrog PF00208.21 KFR06157.1 - 0.053 13.2 1.8 1.8 8.2 0.1 3.0 3 0 0 3 3 3 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 3HCDH PF00725.22 KFR06157.1 - 0.12 12.9 3.3 99 3.6 0.0 4.4 4 0 0 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain TetR_C_27 PF17935.1 KFR06157.1 - 0.2 11.7 2.6 2.9 8.0 0.1 3.2 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain RuvC PF02075.17 KFR06157.1 - 1.2 9.0 6.9 9.6 6.1 0.1 3.5 4 0 0 4 4 3 0 Crossover junction endodeoxyribonuclease RuvC GvpK PF05121.12 KFR06157.1 - 3 8.0 7.7 54 3.9 0.2 4.4 4 0 0 4 4 4 0 Gas vesicle protein K Cation_efflux PF01545.21 KFR06158.1 - 6.2e-38 130.5 7.9 1.5e-37 129.3 7.9 1.6 1 1 0 1 1 1 1 Cation efflux family DUF2721 PF11026.8 KFR06158.1 - 6.7 6.6 9.2 4 7.3 3.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Abhydrolase_2 PF02230.16 KFR06159.1 - 3.2e-37 128.4 0.0 3.6e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KFR06159.1 - 1.5e-07 30.9 0.0 0.00026 20.4 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KFR06159.1 - 3.3e-07 30.4 0.0 0.00035 20.5 0.0 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFR06159.1 - 2.4e-06 27.2 0.7 0.00027 20.5 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 KFR06159.1 - 4.3e-05 23.2 0.0 5.6e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 KFR06159.1 - 0.00014 21.7 0.0 0.00021 21.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KFR06159.1 - 0.00068 19.4 0.0 0.00076 19.2 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 KFR06159.1 - 0.018 14.7 0.1 0.02 14.6 0.1 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 KFR06159.1 - 0.021 14.7 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.20 KFR06159.1 - 0.034 14.2 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain FSH1 PF03959.13 KFR06159.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KFR06159.1 - 0.13 12.8 0.0 0.14 12.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family TGFb_propeptide PF00688.18 KFR06160.1 - 1.9e-36 126.1 0.0 2.5e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 KFR06160.1 - 5.1e-24 85.2 1.3 1.4e-23 83.8 1.3 1.8 1 0 0 1 1 1 1 Transforming growth factor beta like domain SPEG_u2 PF16650.5 KFR06160.1 - 0.76 10.0 4.4 0.16 12.1 0.5 1.8 2 0 0 2 2 2 0 Unstructured region on SPEG complex protein Rrp15p PF07890.12 KFR06161.1 - 5.6e-34 117.4 14.5 1.1e-33 116.5 14.5 1.4 1 0 0 1 1 1 1 Rrp15p IQ PF00612.27 KFR06162.1 - 3.9e-11 41.7 23.9 0.00048 19.7 4.2 3.7 3 0 0 3 3 3 3 IQ calmodulin-binding motif Pfg27 PF09216.10 KFR06162.1 - 0.48 10.2 10.7 1.1 9.0 8.4 2.1 2 0 0 2 2 2 0 Pfg27 DUF3886 PF13025.6 KFR06162.1 - 8.9 6.6 15.9 1.5 9.0 9.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3886) G-patch PF01585.23 KFR06163.1 - 9.3e-17 60.7 1.5 1.9e-16 59.7 1.5 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFR06163.1 - 9.4e-09 35.2 0.4 9.4e-09 35.2 0.4 2.5 3 0 0 3 3 3 1 G-patch domain Hormone_recep PF00104.30 KFR06164.1 - 1.9e-32 112.6 0.4 2.9e-32 112.0 0.4 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFR06164.1 - 6.6e-31 106.6 12.3 1.3e-30 105.7 12.3 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) GAT PF03127.14 KFR06164.1 - 0.19 12.0 2.1 0.6 10.5 0.3 2.4 2 0 0 2 2 2 0 GAT domain Ion_trans_2 PF07885.16 KFR06165.1 - 2.6e-37 126.7 29.5 7.8e-20 70.6 10.9 4.0 3 1 1 4 4 4 3 Ion channel bZIP_Maf PF03131.17 KFR06165.1 - 0.0065 17.0 0.5 0.013 16.0 0.5 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor CENP-F_C_Rb_bdg PF10490.9 KFR06166.1 - 8.6e-15 53.9 0.1 1.5e-14 53.1 0.1 1.4 1 0 0 1 1 1 1 Rb-binding domain of kinetochore protein Cenp-F/LEK1 IFT46_B_C PF12317.8 KFR06166.1 - 0.024 14.4 1.6 0.04 13.6 0.8 1.7 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Atg14 PF10186.9 KFR06166.1 - 4.8 6.2 12.5 0.75 8.8 3.2 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Baculo_PEP_C PF04513.12 KFR06167.1 - 0.0011 19.0 5.0 0.0021 18.1 5.0 1.4 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.8 KFR06167.1 - 0.0036 17.4 12.4 0.0036 17.4 12.4 2.0 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding FliJ PF02050.16 KFR06167.1 - 0.004 17.4 16.7 0.031 14.5 16.7 2.0 1 1 0 1 1 1 1 Flagellar FliJ protein FlaC_arch PF05377.11 KFR06167.1 - 0.0051 17.2 3.8 0.0051 17.2 3.8 2.7 2 1 0 2 2 2 1 Flagella accessory protein C (FlaC) Filament PF00038.21 KFR06167.1 - 0.0078 15.8 19.0 0.013 15.1 8.1 2.0 1 1 1 2 2 2 1 Intermediate filament protein CENP-F_leu_zip PF10473.9 KFR06167.1 - 0.013 15.5 27.1 0.015 15.3 22.0 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.6 KFR06167.1 - 0.025 14.2 24.8 0.029 14.0 15.5 2.0 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 KFR06167.1 - 0.029 13.3 22.6 0.047 12.6 22.6 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein PI3K_P85_iSH2 PF16454.5 KFR06167.1 - 0.032 13.8 18.3 0.04 13.5 18.3 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF1664 PF07889.12 KFR06167.1 - 0.043 13.9 11.3 0.035 14.1 7.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Rab5-bind PF09311.11 KFR06167.1 - 0.047 13.1 19.3 0.015 14.8 14.2 1.8 1 1 1 2 2 2 0 Rabaptin-like protein UPF0242 PF06785.11 KFR06167.1 - 0.055 13.6 24.4 0.081 13.0 12.4 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Tektin PF03148.14 KFR06167.1 - 0.077 11.7 20.0 0.091 11.5 20.0 1.1 1 0 0 1 1 1 0 Tektin family DUF16 PF01519.16 KFR06167.1 - 0.078 13.5 12.3 0.16 12.5 12.1 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 Spectrin PF00435.21 KFR06167.1 - 0.08 13.4 17.5 0.19 12.2 8.1 2.0 1 1 1 2 2 2 0 Spectrin repeat Cob_adeno_trans PF01923.18 KFR06167.1 - 0.097 12.8 6.0 0.23 11.6 6.0 1.7 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Seryl_tRNA_N PF02403.22 KFR06167.1 - 0.11 12.7 20.2 0.5 10.6 7.5 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ArlS_N PF18719.1 KFR06167.1 - 0.13 12.4 13.8 1.4 9.2 4.8 2.1 1 1 1 2 2 2 0 ArlS sensor domain OmpH PF03938.14 KFR06167.1 - 0.18 12.1 16.6 0.29 11.5 16.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CREPT PF16566.5 KFR06167.1 - 0.22 11.7 18.8 0.089 13.0 8.6 2.0 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF3584 PF12128.8 KFR06167.1 - 0.22 9.0 16.1 0.25 8.8 16.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF812 PF05667.11 KFR06167.1 - 0.23 10.3 19.7 0.29 10.0 19.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) RasGAP_C PF03836.15 KFR06167.1 - 0.24 11.5 14.9 0.44 10.7 7.3 2.1 1 1 1 2 2 2 0 RasGAP C-terminus DUF4164 PF13747.6 KFR06167.1 - 0.32 11.3 13.5 3 8.2 13.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Syntaxin-6_N PF09177.11 KFR06167.1 - 0.35 11.5 12.9 1.9 9.1 2.8 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4407 PF14362.6 KFR06167.1 - 0.36 10.1 8.4 0.53 9.6 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cep57_MT_bd PF06657.13 KFR06167.1 - 0.51 10.8 17.6 2.9 8.4 11.0 2.3 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF848 PF05852.11 KFR06167.1 - 0.61 10.2 12.2 1.2 9.3 12.3 1.4 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) FliD_N PF02465.18 KFR06167.1 - 0.66 10.7 11.7 0.11 13.2 4.6 2.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF3450 PF11932.8 KFR06167.1 - 0.69 9.2 16.0 4 6.7 16.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF641 PF04859.12 KFR06167.1 - 0.69 10.3 18.3 0.15 12.4 11.1 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) HIP1_clath_bdg PF16515.5 KFR06167.1 - 0.75 10.4 22.8 1.7 9.3 11.4 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ParB PF08775.10 KFR06167.1 - 0.91 10.0 10.0 0.39 11.2 5.7 2.0 1 1 1 2 2 2 0 ParB family Exonuc_VII_L PF02601.15 KFR06167.1 - 1 8.9 14.3 1.1 8.7 14.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cep57_CLD_2 PF14197.6 KFR06167.1 - 1.1 9.4 21.4 1 9.5 6.0 2.8 1 1 0 2 2 2 0 Centrosome localisation domain of PPC89 AAA_32 PF13654.6 KFR06167.1 - 1.2 7.9 14.1 1.4 7.6 14.1 1.1 1 0 0 1 1 1 0 AAA domain BST2 PF16716.5 KFR06167.1 - 1.2 9.8 21.3 1.9 9.2 8.2 2.1 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Tweety PF04906.13 KFR06167.1 - 1.3 7.6 5.1 1.4 7.5 4.5 1.3 1 1 0 1 1 1 0 Tweety Ax_dynein_light PF10211.9 KFR06167.1 - 1.5 8.8 22.7 14 5.5 19.7 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain RBD-FIP PF09457.10 KFR06167.1 - 1.5 8.8 10.4 0.8 9.7 3.4 3.1 2 2 1 3 3 3 0 FIP domain DUF1640 PF07798.11 KFR06167.1 - 1.5 8.8 19.9 2.7 8.0 19.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Mt_ATP-synt_D PF05873.12 KFR06167.1 - 1.8 8.4 13.2 0.61 9.9 3.7 2.3 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Prominin PF05478.11 KFR06167.1 - 1.8 6.4 11.8 2 6.3 11.8 1.1 1 0 0 1 1 1 0 Prominin FAM76 PF16046.5 KFR06167.1 - 2.3 7.5 17.0 0.14 11.5 10.0 1.9 1 1 1 2 2 2 0 FAM76 protein Golgin_A5 PF09787.9 KFR06167.1 - 2.5 7.5 21.7 9 5.7 21.7 1.7 1 1 0 1 1 1 0 Golgin subfamily A member 5 THOC7 PF05615.13 KFR06167.1 - 2.9 8.2 20.1 1.1 9.5 9.7 2.2 1 1 1 2 2 2 0 Tho complex subunit 7 ApoO PF09769.9 KFR06167.1 - 3.4 7.7 4.5 11 6.0 1.0 2.1 1 1 1 2 2 2 0 Apolipoprotein O AAA_11 PF13086.6 KFR06167.1 - 3.4 7.4 12.9 5.2 6.8 12.9 1.3 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.19 KFR06167.1 - 4.1 5.2 13.2 4.7 5.0 13.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.20 KFR06167.1 - 4.5 7.3 23.7 2.8 8.0 4.3 3.0 1 1 2 3 3 3 0 Prefoldin subunit GrpE PF01025.19 KFR06167.1 - 4.5 6.9 20.7 28 4.3 20.6 1.9 1 1 0 1 1 1 0 GrpE APG6_N PF17675.1 KFR06167.1 - 5.5 7.5 27.1 17 5.9 11.2 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Fib_alpha PF08702.10 KFR06167.1 - 6.6 6.9 14.6 11 6.3 14.6 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 KFR06167.1 - 6.6 5.9 15.5 12 5.0 15.5 1.5 1 1 0 1 1 1 0 TMPIT-like protein YlqD PF11068.8 KFR06167.1 - 7.5 6.9 17.6 1.4 9.3 12.0 1.9 1 1 1 2 2 2 0 YlqD protein LPP PF04728.13 KFR06167.1 - 8 6.9 10.6 16 6.0 3.6 2.7 2 1 0 2 2 2 0 Lipoprotein leucine-zipper DUF724 PF05266.14 KFR06167.1 - 8.3 6.2 18.9 21 4.9 18.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) KELK PF15796.5 KFR06167.1 - 9.8 6.7 23.6 36 4.9 3.0 2.8 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase CENP-F_N PF10481.9 KFR06168.1 - 6e-70 236.3 27.8 6.7e-70 236.2 27.8 1.0 1 0 0 1 1 1 1 Cenp-F N-terminal domain Fez1 PF06818.15 KFR06168.1 - 0.00011 22.7 19.6 0.00013 22.5 19.6 1.0 1 0 0 1 1 1 1 Fez1 Spc7 PF08317.11 KFR06168.1 - 0.0022 16.9 22.4 0.0024 16.8 22.4 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF2514 PF10721.9 KFR06168.1 - 0.0067 16.5 3.1 0.0075 16.3 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2514) TPR_MLP1_2 PF07926.12 KFR06168.1 - 0.027 14.5 25.4 0.096 12.8 11.4 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 KFR06168.1 - 0.028 14.6 23.4 0.12 12.6 23.4 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) OmpH PF03938.14 KFR06168.1 - 0.03 14.7 23.9 0.063 13.6 23.9 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) RACo_linker PF17650.1 KFR06168.1 - 0.057 13.3 1.5 0.3 11.0 0.1 2.4 1 1 1 2 2 2 0 RACo linker region GrpE PF01025.19 KFR06168.1 - 0.064 12.9 18.7 0.14 11.8 18.7 1.5 1 1 0 1 1 1 0 GrpE HGD-D PF06050.13 KFR06168.1 - 0.076 12.8 1.5 0.077 12.7 1.5 1.1 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component V_ATPase_I PF01496.19 KFR06168.1 - 0.083 10.8 13.9 0.09 10.7 13.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PuR_N PF09182.10 KFR06168.1 - 0.085 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal HIP1_clath_bdg PF16515.5 KFR06168.1 - 0.1 13.2 22.8 0.11 13.1 10.8 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FlaC_arch PF05377.11 KFR06168.1 - 0.19 12.2 16.9 1.4 9.3 2.2 3.2 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) CREPT PF16566.5 KFR06168.1 - 0.29 11.3 14.8 0.076 13.2 11.2 1.6 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour PHM7_cyt PF14703.6 KFR06168.1 - 0.3 11.3 7.6 0.36 11.0 7.6 1.2 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Herpes_UL6 PF01763.16 KFR06168.1 - 0.32 9.5 9.1 0.37 9.3 9.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF4407 PF14362.6 KFR06168.1 - 0.44 9.8 12.2 0.51 9.7 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 KFR06168.1 - 0.48 10.0 14.3 0.55 9.7 14.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0242 PF06785.11 KFR06168.1 - 0.53 10.4 20.8 0.67 10.0 20.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FUSC PF04632.12 KFR06168.1 - 0.53 8.7 3.5 0.56 8.7 3.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF848 PF05852.11 KFR06168.1 - 0.61 10.2 12.6 2.5 8.2 12.2 1.9 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) FapA PF03961.13 KFR06168.1 - 0.63 8.6 14.2 0.7 8.4 14.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Uso1_p115_C PF04871.13 KFR06168.1 - 0.88 10.0 24.4 1.7 9.0 21.9 2.0 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Tropomyosin_1 PF12718.7 KFR06168.1 - 1 9.5 25.3 4 7.6 25.3 1.8 1 1 0 1 1 1 0 Tropomyosin like Bacillus_HBL PF05791.11 KFR06168.1 - 1 9.2 14.6 0.27 11.0 9.1 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Calici_MSP PF05752.11 KFR06168.1 - 1.1 9.1 5.9 0.63 9.9 4.1 1.6 1 1 1 2 2 2 0 Calicivirus minor structural protein UPF0231 PF06062.11 KFR06168.1 - 1.1 9.6 12.7 1.2 9.4 6.5 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0231) APG6_N PF17675.1 KFR06168.1 - 1.1 9.8 24.8 6.1 7.4 24.9 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region Prominin PF05478.11 KFR06168.1 - 1.4 6.8 10.6 1.8 6.4 10.6 1.1 1 0 0 1 1 1 0 Prominin YlqD PF11068.8 KFR06168.1 - 1.5 9.2 23.4 1.2e+02 3.0 23.4 2.1 1 1 0 1 1 1 0 YlqD protein ADIP PF11559.8 KFR06168.1 - 1.6 8.8 25.1 3.8 7.6 19.9 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding 5_nucleotid PF05761.14 KFR06168.1 - 1.6 7.6 10.8 1.7 7.4 10.8 1.0 1 0 0 1 1 1 0 5' nucleotidase family FemAB PF02388.16 KFR06168.1 - 1.9 7.3 11.6 2.5 6.9 11.6 1.3 1 0 0 1 1 1 0 FemAB family bZIP_1 PF00170.21 KFR06168.1 - 2 8.6 22.1 2.1 8.5 6.3 3.1 2 1 1 3 3 3 0 bZIP transcription factor DUF641 PF04859.12 KFR06168.1 - 2.2 8.6 17.8 7.4 6.9 6.1 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Macoilin PF09726.9 KFR06168.1 - 2.3 6.7 17.0 2.8 6.4 17.0 1.1 1 0 0 1 1 1 0 Macoilin family DUF2205 PF10224.9 KFR06168.1 - 3.1 7.9 17.0 1.1 9.3 11.8 2.4 1 1 0 2 2 2 0 Short coiled-coil protein CASP_C PF08172.12 KFR06168.1 - 3.8 6.8 16.7 2.6 7.3 11.7 2.2 1 1 1 2 2 2 0 CASP C terminal Atg14 PF10186.9 KFR06168.1 - 4.2 6.4 18.2 6.5 5.7 18.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-H PF05837.12 KFR06168.1 - 4.4 7.8 21.6 7.7 7.0 11.2 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) YabA PF06156.13 KFR06168.1 - 4.6 7.9 17.1 99 3.7 17.1 2.1 1 1 0 1 1 1 0 Initiation control protein YabA JIP_LZII PF16471.5 KFR06168.1 - 4.8 7.4 18.5 4.7 7.4 5.7 3.1 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II Ax_dynein_light PF10211.9 KFR06168.1 - 6.4 6.7 23.8 0.094 12.7 13.6 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain bZIP_2 PF07716.15 KFR06168.1 - 6.6 6.9 24.4 4.4 7.5 8.8 3.1 3 0 0 3 3 3 0 Basic region leucine zipper COG2 PF06148.11 KFR06168.1 - 6.6 6.8 15.0 2.4 8.3 9.1 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cdh1_DBD_1 PF18196.1 KFR06168.1 - 7.5 6.9 14.2 2.8 8.3 10.2 1.9 1 1 1 2 2 2 0 Chromodomain helicase DNA-binding domain 1 DUF1664 PF07889.12 KFR06168.1 - 8 6.5 14.5 9.3 6.3 3.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) LPP PF04728.13 KFR06168.1 - 8.2 6.9 16.9 22 5.5 1.8 2.8 1 1 1 2 2 2 0 Lipoprotein leucine-zipper End3 PF12761.7 KFR06168.1 - 8.3 6.5 21.3 17 5.5 21.3 1.5 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 CENP-Q PF13094.6 KFR06168.1 - 8.3 6.6 21.2 24 5.1 21.2 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DivIC PF04977.15 KFR06168.1 - 8.8 6.2 26.1 5.2 6.9 7.4 3.1 1 1 2 3 3 3 0 Septum formation initiator LRS4 PF10422.9 KFR06168.1 - 9.5 5.7 20.4 10 5.6 20.4 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 SET PF00856.28 KFR06169.1 - 3e-11 44.0 0.0 6e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 SET domain TPR_12 PF13424.6 KFR06169.1 - 2.4e-05 24.5 0.1 0.00029 21.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFR06169.1 - 0.00087 19.1 0.2 0.0033 17.3 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFR06169.1 - 0.0083 16.3 0.1 0.02 15.1 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFR06169.1 - 0.013 16.3 0.4 0.1 13.4 0.0 2.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFR06169.1 - 0.076 13.2 0.4 1.6 9.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat HPD PF05044.12 KFR06170.1 - 8.1e-84 279.1 2.0 1.4e-83 278.3 2.0 1.4 1 0 0 1 1 1 1 Homeo-prospero domain NifQ PF04891.12 KFR06170.1 - 0.016 15.6 3.5 0.48 10.8 0.0 3.4 3 0 0 3 3 3 0 NifQ Metal_resist PF13801.6 KFR06170.1 - 0.25 11.6 9.8 0.31 11.2 8.1 2.0 2 0 0 2 2 2 0 Heavy-metal resistance FliD_N PF02465.18 KFR06170.1 - 0.29 11.9 4.4 8.3 7.2 5.6 2.7 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus AATF-Che1 PF13339.6 KFR06170.1 - 0.45 11.2 9.5 2.1 9.1 9.4 2.2 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor Exonuc_VII_L PF02601.15 KFR06170.1 - 0.69 9.4 6.1 1.4 8.5 6.1 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 KFR06170.1 - 1.1 7.8 3.9 1.7 7.2 3.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2968 PF11180.8 KFR06170.1 - 1.3 8.7 15.8 2.4 7.7 15.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) WDCP PF15390.6 KFR06170.1 - 1.9 6.8 8.8 2.9 6.2 8.8 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Nop25 PF09805.9 KFR06170.1 - 2.8 8.4 18.8 6.1 7.3 18.8 1.6 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) PP_kinase_N PF13089.6 KFR06170.1 - 3.3 8.1 10.9 4.8 7.6 5.3 3.3 2 1 1 3 3 3 0 Polyphosphate kinase N-terminal domain DUF4407 PF14362.6 KFR06170.1 - 5.7 6.2 8.4 9 5.6 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 KFR06171.1 - 3.7e-29 101.9 0.0 1.4e-25 90.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain MIT PF04212.18 KFR06171.1 - 2.8e-18 65.7 0.9 5.3e-18 64.8 0.9 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain PX PF00787.24 KFR06171.1 - 3.1e-12 46.5 0.5 5.8e-12 45.6 0.5 1.4 1 0 0 1 1 1 1 PX domain Pkinase_Tyr PF07714.17 KFR06171.1 - 1.9e-11 43.8 0.0 1.2e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR06171.1 - 5.1e-05 22.7 0.0 9.9e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like USP8_dimer PF08969.11 KFR06171.1 - 0.088 13.0 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 USP8 dimerisation domain Exo_endo_phos PF03372.23 KFR06172.1 - 1.1e-24 87.2 0.0 1.7e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KFR06172.1 - 0.0033 17.2 0.9 0.14 12.0 0.0 3.3 4 0 0 4 4 4 1 Endonuclease-reverse transcriptase MFS_1 PF07690.16 KFR06173.1 - 1.3e-27 96.7 32.2 1.3e-27 96.7 32.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily UL45 PF05473.12 KFR06173.1 - 1.5 8.4 4.0 2.5 7.7 0.1 2.8 3 1 0 3 3 3 0 UL45 protein, carbohydrate-binding C-type lectin-like OATP PF03137.20 KFR06173.1 - 5.2 5.2 15.7 0.029 12.7 4.8 2.3 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TatD_DNase PF01026.21 KFR06174.1 - 1.8e-43 148.8 0.0 2e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Mis14 PF08641.12 KFR06175.1 - 2.2e-20 73.3 0.8 3.5e-20 72.7 0.8 1.3 1 0 0 1 1 1 1 Kinetochore protein Mis14 like bZIP_1 PF00170.21 KFR06176.1 - 5.7e-13 48.8 12.7 6.9e-13 48.5 12.7 1.1 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFR06176.1 - 4e-10 39.6 13.1 5.1e-10 39.3 13.1 1.1 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFR06176.1 - 2.9e-09 37.3 10.1 3.6e-09 37.0 10.1 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor HALZ PF02183.18 KFR06176.1 - 4.8e-05 23.5 1.9 9.6e-05 22.5 1.9 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper HAUS-augmin3 PF14932.6 KFR06176.1 - 0.0033 17.0 0.9 0.0036 16.9 0.9 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 SYCE1 PF15233.6 KFR06176.1 - 0.0044 17.1 5.2 0.0044 17.1 5.2 1.5 1 1 0 1 1 1 1 Synaptonemal complex central element protein 1 TLE_N PF03920.15 KFR06176.1 - 0.0067 16.5 1.7 0.0076 16.3 1.7 1.2 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain HAP1_N PF04849.13 KFR06176.1 - 0.0077 15.5 7.0 0.0085 15.3 7.0 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region TPD52 PF04201.15 KFR06176.1 - 0.0086 15.7 3.3 0.0092 15.6 2.8 1.3 1 1 0 1 1 1 1 Tumour protein D52 family DivIC PF04977.15 KFR06176.1 - 0.0087 15.8 4.6 0.012 15.4 4.6 1.4 1 0 0 1 1 1 1 Septum formation initiator TMF_DNA_bd PF12329.8 KFR06176.1 - 0.012 15.6 8.9 0.015 15.3 8.8 1.3 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Baculo_gp64 PF03273.13 KFR06176.1 - 0.017 13.9 1.0 0.02 13.7 1.0 1.0 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family Prominin PF05478.11 KFR06176.1 - 0.018 13.1 1.0 0.018 13.0 1.0 1.0 1 0 0 1 1 1 0 Prominin Ribosomal_L30_N PF08079.12 KFR06176.1 - 0.019 15.2 9.9 0.025 14.8 9.9 1.1 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain Cnn_1N PF07989.11 KFR06176.1 - 0.021 15.0 6.1 0.021 15.0 6.1 1.4 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 KFR06176.1 - 0.024 15.1 5.3 0.024 15.1 5.3 1.6 1 1 1 2 2 2 0 Cell division protein ZapB CENP-H PF05837.12 KFR06176.1 - 0.025 15.0 3.9 0.03 14.7 3.9 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Rootletin PF15035.6 KFR06176.1 - 0.026 14.5 7.1 0.032 14.2 7.1 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Rx_N PF18052.1 KFR06176.1 - 0.027 14.7 1.6 0.035 14.4 0.9 1.4 1 1 0 1 1 1 0 Rx N-terminal domain JIP_LZII PF16471.5 KFR06176.1 - 0.044 14.0 3.2 0.044 14.0 3.2 1.6 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II DUF3450 PF11932.8 KFR06176.1 - 0.047 13.0 5.9 0.054 12.8 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 KFR06176.1 - 0.051 13.8 11.1 0.065 13.4 11.1 1.0 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Phlebovirus_NSM PF07246.11 KFR06176.1 - 0.056 12.8 2.3 0.056 12.8 2.3 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M FapA PF03961.13 KFR06176.1 - 0.062 11.9 3.9 0.065 11.8 3.9 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_11 PF13086.6 KFR06176.1 - 0.063 13.1 2.7 0.074 12.8 2.7 1.0 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 KFR06176.1 - 0.072 11.7 5.4 0.082 11.5 5.4 1.0 1 0 0 1 1 1 0 AAA domain NYD-SP28_assoc PF14775.6 KFR06176.1 - 0.079 13.1 1.7 0.5 10.5 0.6 2.2 1 1 1 2 2 2 0 Sperm tail C-terminal domain DUF1465 PF07323.12 KFR06176.1 - 0.08 12.8 3.9 0.094 12.6 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) Seryl_tRNA_N PF02403.22 KFR06176.1 - 0.081 13.2 5.5 0.1 12.8 5.5 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 KFR06176.1 - 0.082 12.2 1.9 0.092 12.1 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 KFR06176.1 - 0.1 11.8 4.8 0.11 11.7 4.8 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF2009 PF09418.10 KFR06176.1 - 0.11 11.6 1.9 0.12 11.4 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) TMCO5 PF14992.6 KFR06176.1 - 0.12 12.0 5.0 0.13 11.8 5.0 1.1 1 0 0 1 1 1 0 TMCO5 family TerB PF05099.13 KFR06176.1 - 0.12 12.3 2.4 0.15 12.0 2.4 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TerB DUF2205 PF10224.9 KFR06176.1 - 0.17 11.9 4.8 0.23 11.5 4.8 1.3 1 0 0 1 1 1 0 Short coiled-coil protein RmuC PF02646.16 KFR06176.1 - 0.2 10.8 6.0 0.25 10.5 6.0 1.1 1 0 0 1 1 1 0 RmuC family DUF1515 PF07439.11 KFR06176.1 - 0.31 11.1 2.1 0.41 10.7 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) APG6_N PF17675.1 KFR06176.1 - 0.4 11.2 10.1 0.51 10.9 10.1 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region LCD1 PF09798.9 KFR06176.1 - 0.53 8.7 4.7 0.57 8.6 4.7 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein V_ATPase_I PF01496.19 KFR06176.1 - 0.55 8.1 2.5 0.6 8.0 2.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Vps5 PF09325.10 KFR06176.1 - 0.56 9.7 8.3 0.63 9.5 8.3 1.1 1 0 0 1 1 1 0 Vps5 C terminal like HlyD_2 PF12700.7 KFR06176.1 - 0.59 8.8 5.8 0.66 8.6 5.8 1.0 1 0 0 1 1 1 0 HlyD family secretion protein Cep57_CLD_2 PF14197.6 KFR06176.1 - 1.6 8.9 12.7 0.082 13.0 2.5 2.1 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 UPF0242 PF06785.11 KFR06176.1 - 1.7 8.7 8.0 1.9 8.5 8.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Casc1_N PF15927.5 KFR06176.1 - 1.9 8.1 10.8 2.4 7.8 10.8 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus bZIP_1 PF00170.21 KFR06177.1 - 7.3e-12 45.2 18.2 1.4e-11 44.3 18.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFR06177.1 - 1.1e-09 38.2 19.2 1.7e-09 37.6 19.2 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFR06177.1 - 9.3e-08 32.5 7.9 9.3e-08 32.5 7.9 1.6 2 0 0 2 2 2 1 bZIP Maf transcription factor Dapper PF15268.6 KFR06177.1 - 0.0052 15.7 2.8 0.0054 15.7 2.8 1.0 1 0 0 1 1 1 1 Dapper SNAPc19 PF15497.6 KFR06177.1 - 0.013 15.9 1.1 0.013 15.9 1.1 2.1 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Ribosomal_L6e PF01159.19 KFR06177.1 - 0.047 14.2 6.4 0.11 13.0 6.3 1.6 1 1 1 2 2 2 0 Ribosomal protein L6e Afi1 PF07792.12 KFR06177.1 - 0.11 12.9 3.5 0.17 12.4 3.5 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DivIC PF04977.15 KFR06177.1 - 0.22 11.3 6.8 0.42 10.4 6.8 1.5 1 0 0 1 1 1 0 Septum formation initiator Fungal_TACC PF12709.7 KFR06177.1 - 1 9.9 9.0 1.1 9.7 8.1 1.6 1 1 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins Macoilin PF09726.9 KFR06177.1 - 1.2 7.6 11.8 1.5 7.2 11.8 1.1 1 0 0 1 1 1 0 Macoilin family ALMT PF11744.8 KFR06177.1 - 4.1 6.1 6.3 4.7 5.9 6.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Cyt-b5 PF00173.28 KFR06178.1 - 2.5e-12 46.8 0.0 3.1e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TMEM206 PF15122.6 KFR06179.1 - 2.6e-171 568.5 3.2 3e-171 568.3 3.2 1.0 1 0 0 1 1 1 1 TMEM206 protein family Tetraspanin PF00335.20 KFR06179.1 - 0.016 14.9 0.1 0.055 13.2 0.0 1.8 2 0 0 2 2 2 0 Tetraspanin family OppC_N PF12911.7 KFR06179.1 - 1.2 9.2 3.4 4.9 7.2 0.3 2.7 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C B56 PF01603.20 KFR06180.1 - 2.3e-187 623.0 11.9 2.8e-187 622.8 11.9 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) PRIMA1 PF16101.5 KFR06180.1 - 0.013 15.6 0.5 0.027 14.5 0.5 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Sec7_N PF12783.7 KFR06180.1 - 0.085 12.8 3.7 1.1 9.2 0.2 3.2 2 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Dscam_C PF12355.8 KFR06180.1 - 5.7 7.9 9.9 14 6.7 9.9 1.7 1 1 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal WD40 PF00400.32 KFR06181.1 - 6.7e-26 90.0 12.6 9.5e-06 26.3 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR06181.1 - 1.5e-05 25.2 0.2 0.049 13.9 0.1 4.0 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 PF13646.6 KFR06182.1 - 0.00022 21.5 2.8 0.25 11.8 0.1 4.7 4 0 0 4 4 4 1 HEAT repeats TPR_6 PF13174.6 KFR06182.1 - 0.0047 17.5 1.4 2.2 9.1 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Paz_1 PF18349.1 KFR06182.1 - 0.035 14.1 0.0 0.68 9.9 0.0 2.3 2 0 0 2 2 2 0 PAZ domain DUF3453 PF11935.8 KFR06182.1 - 0.061 12.9 6.0 0.13 11.9 0.1 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF3453) Spindle_Spc25 PF08234.12 KFR06182.1 - 0.13 12.5 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 TPR_2 PF07719.17 KFR06182.1 - 0.22 11.7 0.5 12 6.4 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat SPG48 PF14764.6 KFR06182.1 - 0.39 11.2 5.0 0.32 11.5 0.2 3.4 3 2 0 3 3 3 0 AP-5 complex subunit, vesicle trafficking FANCI_S2 PF14676.6 KFR06182.1 - 1.5 9.1 9.3 2 8.7 1.6 2.9 3 0 0 3 3 3 0 FANCI solenoid 2 Acyltransf_C PF16076.5 KFR06183.1 - 4.1e-16 58.8 0.0 1e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 KFR06183.1 - 4.5e-07 29.5 0.1 7.6e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 Acyltransferase Pkinase PF00069.25 KFR06184.1 - 4e-64 216.5 0.1 1.5e-63 214.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR06184.1 - 2.1e-42 145.2 0.1 1.3e-41 142.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR06184.1 - 4.2e-06 26.3 0.0 8.8e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFR06184.1 - 0.02 14.8 4.0 0.13 12.2 0.1 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF3552 PF12072.8 KFR06184.1 - 0.38 10.1 15.8 0.77 9.1 15.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Exonuc_VII_L PF02601.15 KFR06184.1 - 0.4 10.2 6.1 0.57 9.7 6.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit RD3 PF14473.6 KFR06185.1 - 4.2e-49 165.8 4.2 6e-49 165.2 4.2 1.2 1 0 0 1 1 1 1 RD3 protein Peptidase_S28 PF05577.12 KFR06185.1 - 0.03 13.1 0.1 0.037 12.8 0.1 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 zf-TRAF PF02176.18 KFR06186.1 - 1.1e-23 83.7 25.3 4e-15 56.2 6.3 4.2 3 1 1 4 4 3 2 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 KFR06186.1 - 6.6e-06 25.9 6.7 6.6e-06 25.9 6.7 4.2 5 1 0 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-ACC PF17848.1 KFR06186.1 - 1.3e-05 25.2 3.3 0.0004 20.4 0.2 3.3 2 0 0 2 2 2 1 Acetyl-coA carboxylase zinc finger domain zf-C3HC4 PF00097.25 KFR06186.1 - 2.4e-05 24.1 5.5 2.4e-05 24.1 5.5 4.4 4 1 1 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 KFR06186.1 - 5.3e-05 23.6 8.5 5.3e-05 23.6 8.5 3.4 2 1 0 3 3 2 2 TRAF-like zinc-finger zf-C3HC4_4 PF15227.6 KFR06186.1 - 0.0003 20.9 5.1 0.0003 20.9 5.1 3.6 5 0 0 5 5 4 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KFR06186.1 - 0.00079 19.4 5.0 0.00079 19.4 5.0 3.7 2 1 1 3 3 3 1 RING-type zinc-finger zf_C2HC_14 PF18574.1 KFR06186.1 - 0.0041 16.9 2.0 0.061 13.1 0.7 3.5 2 0 0 2 2 2 1 C2HC Zing finger domain zf-RING_5 PF14634.6 KFR06186.1 - 0.0064 16.4 6.1 0.0064 16.4 6.1 4.5 3 1 1 4 4 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFR06186.1 - 0.0075 16.6 5.6 0.0075 16.6 5.6 3.8 3 1 1 4 4 2 1 Ring finger domain DUF4941 PF16299.5 KFR06186.1 - 0.011 15.0 0.7 0.019 14.3 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4941) zf-RING_6 PF14835.6 KFR06186.1 - 0.014 15.3 1.3 0.014 15.3 1.3 2.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein SMC_ScpA PF02616.14 KFR06186.1 - 0.017 15.0 6.1 0.036 14.0 6.1 1.5 1 0 0 1 1 1 0 Segregation and condensation protein ScpA DUF484 PF04340.12 KFR06186.1 - 0.11 12.2 2.8 0.68 9.6 2.9 2.2 2 1 1 3 3 3 0 Protein of unknown function, DUF484 DUF4279 PF14106.6 KFR06186.1 - 0.19 11.9 3.3 2 8.7 0.7 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) Exonuc_VII_L PF02601.15 KFR06186.1 - 1.3 8.5 6.2 2.2 7.8 6.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Med4 PF10018.9 KFR06186.1 - 6.1 6.5 9.2 9.6 5.8 7.7 1.9 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Myb_DNA-binding PF00249.31 KFR06187.1 - 4.6e-19 68.3 0.0 1.5e-10 41.1 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFR06187.1 - 1.6e-08 34.3 3.6 0.00073 19.4 0.1 3.2 2 1 1 3 3 3 2 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 KFR06187.1 - 3.9e-06 27.0 3.0 0.0018 18.5 0.1 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain ELM2 PF01448.24 KFR06187.1 - 2.7e-05 24.8 0.2 0.00014 22.5 0.0 2.4 2 0 0 2 2 2 1 ELM2 domain Ion_trans PF00520.31 KFR06188.1 - 1.4e-35 122.7 10.2 1.9e-35 122.2 10.2 1.2 1 0 0 1 1 1 1 Ion transport protein PAS_9 PF13426.7 KFR06188.1 - 5.2e-18 65.2 0.1 1.4e-17 63.9 0.1 1.7 1 0 0 1 1 1 1 PAS domain cNMP_binding PF00027.29 KFR06188.1 - 1.6e-14 53.8 0.0 3.6e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KFR06188.1 - 6.9e-12 45.2 3.5 6.9e-12 45.2 3.5 2.0 2 0 0 2 2 2 1 Ion channel PAS PF00989.25 KFR06188.1 - 9.5e-07 28.8 0.1 4.6e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 KFR06188.1 - 2.7e-05 24.4 0.0 8.7e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 PAS fold Cupin_3 PF05899.12 KFR06188.1 - 0.022 14.4 0.1 0.072 12.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF861) PAS_4 PF08448.10 KFR06188.1 - 0.026 14.8 0.0 0.057 13.7 0.0 1.6 1 0 0 1 1 1 0 PAS fold Cupin_2 PF07883.11 KFR06188.1 - 0.033 13.9 0.1 0.082 12.6 0.1 1.6 1 0 0 1 1 1 0 Cupin domain MBOAT PF03062.19 KFR06189.1 - 1.2e-42 146.5 22.6 1.7e-42 146.0 22.6 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family SERTA PF06031.13 KFR06190.1 - 1.7e-15 56.3 0.1 3e-15 55.6 0.1 1.4 1 0 0 1 1 1 1 SERTA motif C2 PF00168.30 KFR06191.1 - 4.2e-21 75.2 0.1 3.3e-13 49.8 0.0 2.2 2 0 0 2 2 2 2 C2 domain Bcr-Abl_Oligo PF09036.10 KFR06191.1 - 0.083 12.9 0.0 0.23 11.5 0.0 1.7 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain UTP25 PF06862.12 KFR06192.1 - 5e-192 638.9 4.6 6.2e-192 638.6 4.6 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 KFR06192.1 - 0.0056 16.5 0.0 0.48 10.2 0.0 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Ribosomal_S10 PF00338.22 KFR06193.1 - 6.9e-27 93.6 0.3 9.5e-27 93.1 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e ClpS PF02617.17 KFR06194.1 - 8e-23 80.0 0.3 2.1e-22 78.7 0.3 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-UBR PF02207.20 KFR06194.1 - 3.1e-21 75.3 7.8 3.1e-21 75.3 7.8 2.6 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) Tetraspanin PF00335.20 KFR06195.1 - 2.2e-28 99.5 3.9 2.9e-28 99.1 3.9 1.1 1 0 0 1 1 1 1 Tetraspanin family MtrD PF04207.12 KFR06195.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit D GLTSCR1 PF15249.6 KFR06197.1 - 1.6e-32 112.0 1.6 5.8e-32 110.2 1.6 2.1 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein PIP49_C PF12260.8 KFR06198.1 - 1.1e-11 44.8 0.0 1.8e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 COX7a PF02238.15 KFR06199.1 - 1.3e-09 38.3 0.0 1.8e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Ion_trans PF00520.31 KFR06200.1 - 0.00017 20.9 1.7 0.00017 20.9 1.7 1.0 1 0 0 1 1 1 1 Ion transport protein 3-HAO PF06052.12 KFR06201.1 - 1.7e-75 251.8 0.2 7.9e-72 239.8 0.3 2.0 2 0 0 2 2 2 2 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KFR06201.1 - 6.7e-13 48.1 0.0 2e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KFR06201.1 - 2.6e-05 23.8 0.1 0.0047 16.6 0.1 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KFR06201.1 - 0.00039 20.3 0.0 0.63 9.9 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain DUF2428 PF10350.9 KFR06202.1 - 7.6e-104 346.8 1.0 7.6e-104 346.8 1.0 2.0 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 KFR06202.1 - 0.0029 17.7 1.8 45 4.7 0.0 6.5 7 0 0 7 7 7 1 HEAT repeat MyTH4 PF00784.17 KFR06203.1 - 1.3e-33 115.7 1.6 1.3e-33 115.7 1.6 2.6 3 0 0 3 3 3 1 MyTH4 domain PH PF00169.29 KFR06203.1 - 1.8e-27 95.9 0.7 8e-19 68.1 0.1 3.8 3 0 0 3 3 3 2 PH domain FERM_M PF00373.18 KFR06203.1 - 4.2e-13 49.7 0.1 4.2e-13 49.7 0.1 2.3 2 0 0 2 2 2 1 FERM central domain PH_11 PF15413.6 KFR06203.1 - 3.6e-06 27.3 1.5 3.6e-06 27.3 1.5 4.6 4 1 0 4 4 4 1 Pleckstrin homology domain DLIC PF05783.11 KFR06204.1 - 1.8e-11 43.5 0.1 1.3e-09 37.5 0.0 2.1 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) Roc PF08477.13 KFR06204.1 - 0.0078 16.4 0.0 0.019 15.2 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KFR06204.1 - 0.0082 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KFR06204.1 - 0.016 14.7 0.0 0.036 13.5 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family DMAP1_like PF17024.5 KFR06204.1 - 0.084 13.0 0.4 0.33 11.1 0.4 2.0 1 1 0 1 1 1 0 Putative DMAP1-like Elongin_A PF06881.11 KFR06204.1 - 0.46 11.0 3.7 6.8 7.3 1.9 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A ABC_tran PF00005.27 KFR06205.1 - 7.4e-30 104.3 0.0 1.2e-29 103.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KFR06205.1 - 9.5e-21 74.2 10.0 1.6e-20 73.4 10.0 1.4 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 KFR06205.1 - 4.5e-06 26.7 3.7 0.029 14.2 0.6 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFR06205.1 - 1.7e-05 24.4 0.2 3.6e-05 23.4 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KFR06205.1 - 2.9e-05 24.7 0.0 4.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 KFR06205.1 - 9.6e-05 21.9 0.9 0.0015 18.0 0.9 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFR06205.1 - 0.0057 17.1 0.0 0.011 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFR06205.1 - 0.0061 16.5 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase NTPase_1 PF03266.15 KFR06205.1 - 0.013 15.4 0.1 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 KFR06205.1 - 0.037 13.2 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Rad17 PF03215.15 KFR06205.1 - 0.066 13.1 0.1 0.19 11.7 0.1 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain NACHT PF05729.12 KFR06205.1 - 0.08 12.9 0.1 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 KFR06205.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MobB PF03205.14 KFR06205.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF5524 PF17662.1 KFR06205.1 - 0.26 10.6 0.0 0.38 10.1 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5524) PPR_2 PF13041.6 KFR06206.1 - 4.4e-36 122.8 19.5 2.6e-07 30.7 0.0 14.9 12 1 3 15 15 15 8 PPR repeat family PPR PF01535.20 KFR06206.1 - 2.9e-29 99.2 39.6 0.0022 18.1 0.0 18.5 19 0 0 19 19 19 6 PPR repeat PPR_3 PF13812.6 KFR06206.1 - 7.7e-25 86.8 11.6 3.9e-08 33.3 0.0 11.3 9 2 5 14 14 13 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 KFR06206.1 - 2.8e-23 81.3 15.1 9e-06 25.3 0.0 10.0 11 0 0 11 11 11 6 PPR repeat PPR_long PF17177.4 KFR06206.1 - 2.1e-22 79.6 12.1 9.7e-06 25.1 0.0 8.8 5 3 4 9 9 9 5 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KFR06206.1 - 1.6e-05 25.3 4.1 94 4.2 0.0 8.5 9 1 1 10 10 10 0 Tetratricopeptide repeat ATP13 PF12921.7 KFR06206.1 - 5.3e-05 23.0 0.6 1 9.2 0.0 6.0 5 2 2 7 7 7 1 Mitochondrial ATPase expression TPR_8 PF13181.6 KFR06206.1 - 0.00035 20.5 2.9 9.1 6.8 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFR06206.1 - 0.00036 21.0 16.2 10 6.7 0.0 9.4 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFR06206.1 - 0.00036 21.1 0.1 62 4.3 0.1 6.5 8 0 0 8 8 8 0 Tetratricopeptide repeat AAA_lid_8 PF17868.1 KFR06206.1 - 0.19 11.7 1.1 5.6 6.9 0.0 3.6 4 0 0 4 4 4 0 AAA lid domain TPR_2 PF07719.17 KFR06206.1 - 0.21 11.8 2.7 84 3.7 0.1 5.1 5 0 0 5 5 3 0 Tetratricopeptide repeat ECSIT PF06239.11 KFR06206.1 - 0.32 10.1 4.0 6.4 5.8 0.0 3.7 5 0 0 5 5 5 0 Evolutionarily conserved signalling intermediate in Toll pathway PP2C PF00481.21 KFR06207.1 - 2.4e-83 279.8 0.0 2.9e-83 279.4 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.13 KFR06207.1 - 4.7e-31 107.1 0.1 9e-31 106.2 0.1 1.5 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain PP2C_2 PF13672.6 KFR06207.1 - 0.0018 17.9 0.0 0.0056 16.3 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KFR06207.1 - 0.0028 17.6 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Alpha-amylase PF00128.24 KFR06208.1 - 1.1e-77 261.9 1.8 1.5e-77 261.4 1.8 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain SLC3A2_N PF16028.5 KFR06208.1 - 1.3e-05 24.6 0.8 2.5e-05 23.7 0.8 1.4 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus Nup35_RRM_2 PF14605.6 KFR06208.1 - 0.082 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Peptidase_S9 PF00326.21 KFR06209.1 - 3.2e-32 111.7 0.0 5.2e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 KFR06209.1 - 2.2e-25 89.4 3.1 4.4e-25 88.3 3.1 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Hydrolase_4 PF12146.8 KFR06209.1 - 0.014 14.6 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Methyltransf_16 PF10294.9 KFR06210.1 - 6.1e-17 61.9 0.1 7.4e-17 61.6 0.1 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_11 PF08241.12 KFR06210.1 - 0.00038 21.1 0.0 0.00063 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFR06210.1 - 0.00057 20.5 0.0 0.00096 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFR06210.1 - 0.0019 18.0 0.0 0.0039 17.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain FAE1_CUT1_RppA PF08392.12 KFR06210.1 - 0.0021 17.4 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein Methyltransf_12 PF08242.12 KFR06210.1 - 0.0091 16.7 0.1 0.028 15.1 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFR06210.1 - 0.14 11.7 0.2 0.27 10.8 0.2 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Sensor_TM1 PF13755.6 KFR06210.1 - 0.16 11.7 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain Tex_N PF09371.10 KFR06211.1 - 2.3e-48 164.3 0.5 4.3e-48 163.4 0.5 1.4 1 0 0 1 1 1 1 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 KFR06211.1 - 1.4e-44 151.6 0.0 3.7e-44 150.2 0.0 1.8 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_3 PF12836.7 KFR06211.1 - 8.3e-25 86.8 0.0 2.2e-24 85.5 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif S1 PF00575.23 KFR06211.1 - 1.3e-09 38.3 0.3 2.8e-09 37.2 0.3 1.6 1 0 0 1 1 1 1 S1 RNA binding domain HHH_9 PF17674.1 KFR06211.1 - 5.9e-09 36.7 2.0 9.8e-09 36.0 0.0 2.6 3 0 0 3 3 3 1 HHH domain HHH_7 PF14635.6 KFR06211.1 - 2.9e-06 27.6 0.0 9e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 KFR06211.1 - 8.6e-06 25.6 0.0 2.1e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_6 PF14579.6 KFR06211.1 - 0.0072 16.6 0.4 0.073 13.3 0.0 2.8 3 1 0 3 3 3 1 Helix-hairpin-helix motif RuvX PF03652.15 KFR06211.1 - 0.05 14.0 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 Holliday junction resolvase C2 PF00168.30 KFR06212.1 - 2.1e-15 56.9 0.0 2.3e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 C2 domain PAS_3 PF08447.12 KFR06214.1 - 2.3e-27 95.1 0.0 1.3e-20 73.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KFR06214.1 - 2.3e-22 79.2 0.2 4.9e-19 68.5 0.1 2.5 2 0 0 2 2 2 2 PAS domain HIF-1a_CTAD PF08778.10 KFR06214.1 - 2.7e-19 68.5 1.0 7.3e-19 67.1 1.0 1.8 1 0 0 1 1 1 1 HIF-1 alpha C terminal transactivation domain HIF-1 PF11413.8 KFR06214.1 - 9.5e-18 63.3 2.1 2e-17 62.2 2.1 1.6 1 0 0 1 1 1 1 Hypoxia-inducible factor-1 PAS PF00989.25 KFR06214.1 - 4.5e-14 52.4 0.0 3e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KFR06214.1 - 2.3e-08 34.2 0.0 0.0074 16.5 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KFR06214.1 - 4.4e-07 30.1 0.0 0.038 14.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 KFR06214.1 - 0.076 13.0 0.4 0.14 12.1 0.4 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Corona_I PF03187.14 KFR06214.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Corona nucleocapsid I protein TMEM247 PF15444.6 KFR06215.1 - 2.3e-07 31.1 0.2 2.4e-07 31.0 0.2 1.1 1 0 0 1 1 1 1 Transmembrane protein 247 Ras PF00071.22 KFR06216.1 - 5.5e-27 94.3 0.0 6.3e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR06216.1 - 7.3e-05 23.0 0.0 0.00011 22.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase PIG-F PF06699.11 KFR06217.1 - 7.6e-42 143.5 13.8 9.9e-42 143.1 13.8 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Ndc1_Nup PF09531.10 KFR06217.1 - 3.2 6.3 19.3 9.3 4.8 19.2 1.5 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Cript PF10235.9 KFR06218.1 - 6.6e-25 87.5 0.7 7.3e-25 87.4 0.7 1.0 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT NKAIN PF05640.14 KFR06221.1 - 7.6e-39 133.1 1.5 8.3e-39 133.0 1.5 1.0 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein NKAIN PF05640.14 KFR06222.1 - 2.4e-24 85.7 4.1 2.5e-24 85.7 4.1 1.0 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein Asp_Arg_Hydrox PF05118.15 KFR06223.1 - 3.7e-56 189.3 0.4 7.6e-56 188.3 0.4 1.6 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Asp-B-Hydro_N PF05279.11 KFR06223.1 - 2.2e-52 178.6 0.2 2.2e-52 178.6 0.2 2.0 2 0 0 2 2 2 1 Aspartyl beta-hydroxylase N-terminal region TPR_6 PF13174.6 KFR06223.1 - 2.7e-08 33.9 4.1 0.011 16.3 0.1 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFR06223.1 - 4.8e-08 32.5 7.1 0.032 14.3 0.0 6.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFR06223.1 - 1.5e-07 31.6 0.0 0.014 16.2 0.2 4.8 4 1 2 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFR06223.1 - 2e-07 30.7 3.0 0.045 14.0 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFR06223.1 - 1e-06 29.3 0.7 0.001 19.7 1.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFR06223.1 - 1.4e-05 25.3 0.1 0.28 11.5 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFR06223.1 - 2e-05 24.2 4.0 0.22 11.4 0.0 6.3 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFR06223.1 - 0.00011 22.6 0.3 0.16 12.5 0.3 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFR06223.1 - 0.00029 20.4 5.5 0.089 12.5 0.1 5.1 5 1 1 6 6 6 1 TPR repeat YfiO PF13525.6 KFR06223.1 - 0.011 15.5 0.4 0.1 12.3 0.4 2.5 2 1 0 2 2 2 0 Outer membrane lipoprotein SNAP PF14938.6 KFR06223.1 - 0.015 14.7 0.2 0.03 13.8 0.2 1.4 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP ATG27 PF09451.10 KFR06223.1 - 0.026 14.4 0.2 0.055 13.3 0.2 1.5 1 0 0 1 1 1 0 Autophagy-related protein 27 LUC7 PF03194.15 KFR06223.1 - 0.057 13.1 0.5 0.13 12.0 0.5 1.5 1 0 0 1 1 1 0 LUC7 N_terminus TPR_7 PF13176.6 KFR06223.1 - 0.079 13.0 0.9 22 5.4 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat CTNNBL PF08216.11 KFR06223.1 - 0.48 10.6 6.9 0.15 12.3 1.0 2.5 2 1 1 3 3 3 0 Catenin-beta-like, Arm-motif containing nuclear CRAL_TRIO PF00650.20 KFR06224.1 - 3.7e-34 117.8 0.0 5.8e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFR06224.1 - 3e-08 33.9 0.0 4.9e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFR06224.1 - 1.4e-06 28.4 0.1 2.8e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Ras PF00071.22 KFR06225.1 - 3.8e-57 192.4 0.0 4.4e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR06225.1 - 4e-30 104.5 0.0 6.5e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR06225.1 - 6.7e-12 45.2 0.0 7.5e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFR06225.1 - 0.00075 19.1 0.0 0.00096 18.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFR06225.1 - 0.0018 17.7 0.0 0.002 17.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFR06225.1 - 0.0063 16.6 0.0 0.01 15.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFR06225.1 - 0.0068 16.3 0.1 1.3 8.9 0.0 2.3 1 1 2 3 3 3 2 RsgA GTPase Carb_anhydrase PF00194.21 KFR06226.1 - 3.1e-79 266.1 0.0 3.4e-79 266.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase HMG_box PF00505.19 KFR06228.1 - 8.6e-18 64.5 0.4 2e-17 63.3 0.4 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFR06228.1 - 8.3e-12 45.5 0.6 1.7e-11 44.5 0.6 1.5 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.13 KFR06228.1 - 0.014 16.0 0.9 0.031 14.8 0.2 1.9 1 1 0 1 1 1 0 YABBY protein Mitofilin PF09731.9 KFR06228.1 - 0.1 11.4 5.6 0.13 11.1 5.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PDZ_6 PF17820.1 KFR06229.1 - 1.4e-23 82.5 0.3 3e-14 52.6 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 KFR06229.1 - 3.8e-21 75.2 1.9 4.3e-13 49.4 0.1 2.8 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 KFR06229.1 - 1.4e-12 47.8 0.2 2.2e-07 31.1 0.0 2.3 2 0 0 2 2 2 2 PDZ domain p450 PF00067.22 KFR06230.1 - 6.2e-77 259.3 0.5 7.8e-77 259.0 0.5 1.0 1 0 0 1 1 1 1 Cytochrome P450 SEP PF08059.13 KFR06231.1 - 2e-28 98.7 0.3 5.3e-28 97.4 0.1 1.8 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 KFR06231.1 - 8.5e-18 64.3 0.3 1.4e-17 63.6 0.3 1.3 1 0 0 1 1 1 1 UBX domain Phage_capsid PF05065.13 KFR06231.1 - 0.065 12.5 0.0 0.099 11.9 0.0 1.2 1 0 0 1 1 1 0 Phage capsid family FAM110_N PF14161.6 KFR06232.1 - 8.4e-44 148.2 3.7 2.1e-43 146.9 3.7 1.7 1 0 0 1 1 1 1 Centrosome-associated N terminus FAM110_C PF14160.6 KFR06232.1 - 2.3e-33 115.6 0.3 2.3e-33 115.6 0.3 2.0 2 0 0 2 2 2 1 Centrosome-associated C terminus Inositol_P PF00459.25 KFR06235.1 - 2.1e-34 119.3 0.2 2.4e-34 119.1 0.2 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family RuvA_N PF01330.21 KFR06235.1 - 0.02 15.0 0.1 0.043 13.9 0.1 1.5 1 0 0 1 1 1 0 RuvA N terminal domain Opiods_neuropep PF01160.18 KFR06236.1 - 5.3e-18 64.8 2.3 8.2e-18 64.2 2.3 1.3 1 0 0 1 1 1 1 Vertebrate endogenous opioids neuropeptide Op_neuropeptide PF08035.11 KFR06236.1 - 0.0074 16.1 40.5 0.77 9.7 0.2 7.2 7 0 0 7 7 7 6 Opioids neuropeptide SRF-TF PF00319.18 KFR06236.1 - 0.68 9.5 7.7 1.8 8.1 0.3 3.1 4 0 0 4 4 4 0 SRF-type transcription factor (DNA-binding and dimerisation domain) adh_short PF00106.25 KFR06237.1 - 8.5e-44 149.4 0.1 1e-43 149.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFR06237.1 - 1.1e-36 126.5 0.1 1.4e-36 126.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFR06237.1 - 3.1e-09 37.0 0.1 4.4e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KFR06238.1 - 1.2e-49 168.5 0.1 1.3e-49 168.3 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFR06238.1 - 2.6e-33 115.5 0.1 3.1e-33 115.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFR06238.1 - 2.2e-11 44.0 0.1 2.9e-11 43.6 0.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFR06238.1 - 0.0087 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KFR06238.1 - 0.036 13.5 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.23 KFR06238.1 - 0.071 13.2 0.7 0.1 12.7 0.1 1.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KFR06238.1 - 0.14 11.5 0.2 0.35 10.2 0.1 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MTCP1 PF08991.10 KFR06239.1 - 0.00063 19.9 0.5 0.00071 19.8 0.5 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CEP1-DNA_bind PF09287.10 KFR06239.1 - 0.0016 18.1 0.1 0.002 17.8 0.1 1.1 1 0 0 1 1 1 1 CEP-1, DNA binding TAP_C PF03943.13 KFR06239.1 - 0.11 12.1 0.2 0.16 11.6 0.2 1.2 1 0 0 1 1 1 0 TAP C-terminal domain CHCH PF06747.13 KFR06239.1 - 0.25 11.5 3.5 0.37 11.0 3.5 1.3 1 0 0 1 1 1 0 CHCH domain zf-H2C2_2 PF13465.6 KFR06240.1 - 2.7e-25 87.6 56.2 3.7e-05 23.9 1.0 8.5 8 0 0 8 8 8 8 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR06240.1 - 2e-24 84.1 58.0 0.00058 20.5 1.1 7.5 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2 PF00096.26 KFR06240.1 - 5.4e-23 80.1 64.8 6.1e-05 23.3 1.4 7.6 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFR06240.1 - 1.6e-05 24.7 51.8 0.023 14.7 0.6 7.3 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFR06240.1 - 2.3e-05 24.6 45.1 0.032 14.5 1.1 7.1 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFR06240.1 - 0.00027 21.2 26.9 0.29 11.6 0.7 5.8 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFR06240.1 - 0.0021 18.3 30.4 0.038 14.3 10.3 4.3 1 1 2 3 3 3 2 C2H2-type zinc ribbon Acyltransf_C PF16076.5 KFR06240.1 - 0.0052 16.8 3.8 0.92 9.6 0.7 2.7 2 0 0 2 2 2 2 Acyltransferase C-terminus zf-C2H2_11 PF16622.5 KFR06240.1 - 0.035 13.9 0.0 0.035 13.9 0.0 6.6 8 0 0 8 8 8 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KFR06240.1 - 0.1 13.0 40.8 1.1 9.6 1.4 5.5 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KFR06240.1 - 2 8.3 8.7 1.2e+02 2.6 0.0 5.1 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-LITAF-like PF10601.9 KFR06240.1 - 7.3 6.9 14.9 0.25 11.6 2.4 3.7 3 1 0 3 3 3 0 LITAF-like zinc ribbon domain zf-Di19 PF05605.12 KFR06240.1 - 9.2 6.6 37.2 0.8 10.0 1.1 5.0 1 1 6 7 7 7 0 Drought induced 19 protein (Di19), zinc-binding Pkinase PF00069.25 KFR06241.1 - 6.6e-45 153.5 0.0 9.5e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR06241.1 - 3.9e-40 137.8 0.0 4.7e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR06241.1 - 0.0033 16.8 0.0 0.007 15.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFR06241.1 - 0.076 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Ribosomal_S10 PF00338.22 KFR06242.1 - 4.7e-31 106.9 0.3 5.6e-31 106.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Kinesin PF00225.23 KFR06243.1 - 1.5e-97 326.6 0.4 2.3e-97 325.9 0.4 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFR06243.1 - 1.6e-13 50.8 7.7 4.7e-13 49.3 0.1 3.4 4 1 0 4 4 4 2 Microtubule binding DNA_pol3_delt_C PF14840.6 KFR06243.1 - 0.079 13.3 0.4 1.5 9.1 0.3 2.3 2 0 0 2 2 2 0 Processivity clamp loader gamma complex DNA pol III C-term Pkinase_Tyr PF07714.17 KFR06244.1 - 2.4e-96 322.0 0.0 3e-96 321.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR06244.1 - 2.8e-48 164.6 0.0 4e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFR06244.1 - 8.9e-24 83.4 0.0 1.8e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFR06244.1 - 1.1e-16 60.2 0.1 2.4e-16 59.0 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFR06244.1 - 1.2e-08 34.5 0.4 4.2e-08 32.7 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KFR06244.1 - 2.2e-08 33.8 0.0 5.8e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFR06244.1 - 0.0035 17.6 0.1 0.0072 16.6 0.1 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain Haspin_kinase PF12330.8 KFR06244.1 - 0.019 13.9 0.1 0.042 12.8 0.1 1.5 1 1 0 1 1 1 0 Haspin like kinase domain DUF2070 PF09843.9 KFR06244.1 - 0.12 10.6 0.0 0.16 10.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Acyltransferase PF01553.21 KFR06245.1 - 6e-08 32.4 0.0 2.2e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 Acyltransferase DAGAT PF03982.13 KFR06245.1 - 5.8e-05 22.2 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol acyltransferase XK-related PF09815.9 KFR06246.1 - 3.8e-105 351.7 25.9 4.4e-105 351.5 25.9 1.0 1 0 0 1 1 1 1 XK-related protein PLAT PF01477.23 KFR06249.1 - 2.7e-18 66.6 0.0 4.4e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 PLAT/LH2 domain DCX PF03607.17 KFR06250.1 - 1.4e-36 124.3 0.0 1.4e-20 73.1 0.0 2.6 2 0 0 2 2 2 2 Doublecortin Rep_Org_C PF06926.11 KFR06250.1 - 0.04 14.2 1.1 0.34 11.2 0.0 2.8 2 0 0 2 2 2 0 Putative replisome organiser protein C-terminus Ribosomal_L27A PF00828.19 KFR06251.1 - 4.9e-28 98.4 0.0 6.8e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Abhydrolase_2 PF02230.16 KFR06252.1 - 8.5e-74 248.0 0.0 9.5e-74 247.9 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KFR06252.1 - 2.4e-06 27.0 0.0 0.0015 17.9 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KFR06252.1 - 5.8e-06 26.3 0.0 8e-05 22.6 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KFR06252.1 - 0.00043 20.0 0.0 0.00043 20.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.22 KFR06252.1 - 0.0024 17.9 0.0 0.0042 17.1 0.0 1.4 1 0 0 1 1 1 1 Cutinase DUF2974 PF11187.8 KFR06252.1 - 0.0047 16.5 0.0 0.0063 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DLH PF01738.18 KFR06252.1 - 0.009 15.6 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KFR06252.1 - 0.015 15.9 0.0 0.015 15.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KFR06252.1 - 0.015 14.8 0.0 4.7 6.6 0.0 2.1 1 1 1 2 2 2 0 Prolyl oligopeptidase family FSH1 PF03959.13 KFR06252.1 - 0.042 13.5 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Lipase_3 PF01764.25 KFR06252.1 - 0.059 13.2 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.20 KFR06252.1 - 0.067 12.8 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF2920 PF11144.8 KFR06252.1 - 0.07 12.3 0.0 0.17 11.0 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) AXE1 PF05448.12 KFR06252.1 - 0.14 10.8 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) TFIIS_M PF07500.14 KFR06253.1 - 2.6e-37 127.7 2.0 2.6e-37 127.7 2.0 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KFR06253.1 - 2.7e-19 68.7 8.0 5.9e-19 67.6 8.0 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KFR06253.1 - 4.2e-11 42.7 0.7 1.5e-10 40.9 0.7 2.0 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DBD_Tnp_Mut PF03108.15 KFR06253.1 - 0.0016 18.4 0.2 0.0041 17.1 0.2 1.6 1 0 0 1 1 1 1 MuDR family transposase Ku_C PF03730.14 KFR06253.1 - 3.5 8.4 10.1 0.23 12.2 3.0 2.5 2 1 0 2 2 2 0 Ku70/Ku80 C-terminal arm RGS PF00615.19 KFR06254.1 - 6.4e-35 120.0 1.3 8.5e-35 119.6 1.3 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain V-ATPase_H_N PF03224.14 KFR06255.1 - 5.4e-105 351.2 5.8 5.4e-105 351.2 5.8 1.5 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KFR06255.1 - 5e-29 100.8 0.0 5e-29 100.8 0.0 2.6 3 0 0 3 3 3 1 V-ATPase subunit H Arm PF00514.23 KFR06255.1 - 3.2e-07 30.2 0.1 0.00045 20.2 0.0 4.0 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat DUF2326 PF10088.9 KFR06255.1 - 0.012 15.4 0.1 0.038 13.7 0.1 1.9 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2326) YlbD_coat PF14071.6 KFR06255.1 - 0.013 15.8 1.4 0.013 15.8 1.4 2.0 2 0 0 2 2 2 0 Putative coat protein UCH PF00443.29 KFR06255.1 - 0.038 13.5 1.5 0.058 12.9 1.5 1.5 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Muted PF14942.6 KFR06255.1 - 0.41 11.0 7.1 0.44 10.9 1.3 2.4 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein RVT_1 PF00078.27 KFR06256.1 - 0.001 18.6 0.1 0.0018 17.8 0.1 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) 7tm_1 PF00001.21 KFR06257.1 - 3.3e-60 203.7 21.6 3.8e-60 203.4 21.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFR06257.1 - 7.9e-09 35.3 14.7 1e-08 34.9 14.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.9 KFR06257.1 - 9.7e-08 31.7 20.8 1.2e-07 31.4 20.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFR06257.1 - 0.013 15.1 21.8 0.013 15.1 20.1 1.8 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Saf_2TM PF18303.1 KFR06257.1 - 0.63 9.6 4.9 0.13 11.8 0.8 2.0 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain ATG11 PF10377.9 KFR06258.1 - 2.1e-25 89.3 0.0 2.1e-25 89.3 0.0 5.8 6 2 2 8 8 8 1 Autophagy-related protein 11 TBK1_ULD PF18396.1 KFR06258.1 - 0.0016 18.3 0.1 0.015 15.2 0.0 2.6 2 0 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain NPBW PF15180.6 KFR06258.1 - 0.47 10.3 4.3 0.39 10.6 1.0 2.7 2 0 0 2 2 2 0 Neuropeptides B and W MYT1 PF08474.11 KFR06261.1 - 2e-84 283.3 6.6 2e-84 283.3 6.6 2.2 2 0 0 2 2 2 1 Myelin transcription factor 1 zf-C2HC PF01530.18 KFR06261.1 - 1.7e-82 271.1 80.1 1.1e-15 57.5 7.4 6.6 6 0 0 6 6 6 6 Zinc finger, C2HC type DUF1664 PF07889.12 KFR06261.1 - 0.035 14.1 0.7 0.13 12.3 0.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) SlyX PF04102.12 KFR06261.1 - 0.076 13.6 3.9 0.31 11.7 3.9 2.0 1 0 0 1 1 1 0 SlyX Prefoldin PF02996.17 KFR06261.1 - 0.13 12.2 4.5 0.17 11.8 2.0 2.5 2 0 0 2 2 2 0 Prefoldin subunit YabA PF06156.13 KFR06261.1 - 0.15 12.7 8.0 0.072 13.7 3.6 2.8 2 0 0 2 2 2 0 Initiation control protein YabA Tho2 PF11262.8 KFR06261.1 - 0.19 10.9 2.6 0.41 9.8 2.6 1.5 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 TMF_DNA_bd PF12329.8 KFR06261.1 - 0.41 10.7 15.2 2.1 8.4 15.2 2.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding zf-RAG1 PF10426.9 KFR06261.1 - 0.46 10.7 8.2 10 6.4 0.0 5.4 5 0 0 5 5 5 0 Recombination-activating protein 1 zinc-finger domain DUF16 PF01519.16 KFR06261.1 - 0.46 11.0 3.9 0.9 10.1 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 ADIP PF11559.8 KFR06261.1 - 0.49 10.5 10.1 0.048 13.8 4.1 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Chisel PF15355.6 KFR06261.1 - 0.5 10.6 2.9 1.4 9.2 1.0 2.8 2 0 0 2 2 2 0 Stretch-responsive small skeletal muscle X protein, Chisel FapA PF03961.13 KFR06261.1 - 0.59 8.7 7.2 0.25 9.9 4.5 1.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A IBR PF01485.21 KFR06261.1 - 1.8 8.9 20.9 19 5.5 0.2 6.4 3 2 3 6 6 6 0 IBR domain, a half RING-finger domain Syntaxin-6_N PF09177.11 KFR06261.1 - 2.4 8.7 8.9 13 6.4 0.1 3.7 3 0 0 3 3 3 0 Syntaxin 6, N-terminal DUF2408 PF10303.9 KFR06261.1 - 6.5 7.3 8.3 0.44 11.1 1.8 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF2408) PCMT PF01135.19 KFR06262.1 - 1.6e-28 99.9 0.0 2.2e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SOCS_box PF07525.16 KFR06262.1 - 1e-06 29.0 1.2 0.011 16.1 0.8 2.6 2 0 0 2 2 2 2 SOCS box DOT1 PF08123.13 KFR06262.1 - 0.00013 21.6 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 KFR06262.1 - 0.0027 17.5 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 KFR06262.1 - 0.0065 16.2 0.0 0.018 14.8 0.0 1.6 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_25 PF13649.6 KFR06262.1 - 0.014 16.1 0.0 0.033 14.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CysA_C_terminal PF17850.1 KFR06263.1 - 0.16 12.6 5.5 47 4.6 0.1 3.5 1 1 1 2 2 2 0 CysA C-terminal regulatory domain DUF4462 PF14692.6 KFR06264.1 - 0.12 11.9 0.3 0.19 11.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) PDZ PF00595.24 KFR06265.1 - 3.9e-17 62.4 0.7 6.9e-17 61.6 0.7 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFR06265.1 - 1.2e-07 31.5 0.4 2.9e-07 30.2 0.1 1.8 2 0 0 2 2 2 1 PDZ domain PH PF00169.29 KFR06265.1 - 0.0004 20.8 4.6 0.23 12.0 0.3 3.2 2 1 1 3 3 3 2 PH domain Tricorn_PDZ PF14685.6 KFR06265.1 - 0.16 11.9 0.1 0.83 9.7 0.0 2.1 2 0 0 2 2 2 0 Tricorn protease PDZ domain PDZ_2 PF13180.6 KFR06265.1 - 0.2 12.0 0.0 0.4 11.1 0.0 1.4 1 0 0 1 1 1 0 PDZ domain DUF4462 PF14692.6 KFR06266.1 - 0.1 12.1 0.3 0.19 11.2 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Voltage_CLC PF00654.20 KFR06267.1 - 2.4e-22 79.7 7.6 2.6e-22 79.5 7.6 1.0 1 0 0 1 1 1 1 Voltage gated chloride channel UQ_con PF00179.26 KFR06268.1 - 2e-18 66.4 0.0 2.2e-18 66.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFR06268.1 - 0.032 14.5 0.0 0.034 14.4 0.0 1.2 1 0 0 1 1 1 0 RWD domain MCM PF00493.23 KFR06269.1 - 6.5e-100 332.8 0.0 9.4e-100 332.3 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFR06269.1 - 5e-40 136.3 0.4 8.9e-40 135.4 0.4 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFR06269.1 - 2.2e-26 92.1 2.4 3.3e-26 91.5 1.1 2.1 2 0 0 2 2 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFR06269.1 - 6.5e-19 68.4 3.5 1.7e-18 67.1 1.0 2.6 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFR06269.1 - 3.8e-08 33.0 0.0 1.6e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFR06269.1 - 4.3e-08 33.3 0.1 4.1e-07 30.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFR06269.1 - 2.8e-05 24.0 0.0 6.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CDT1_C PF16679.5 KFR06269.1 - 0.0043 17.5 0.1 0.018 15.5 0.1 2.0 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain Sigma54_activat PF00158.26 KFR06269.1 - 0.013 15.3 0.0 3 7.5 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 KFR06269.1 - 0.022 15.2 0.0 0.063 13.7 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KFR06269.1 - 0.079 12.9 0.3 6.5 6.6 0.0 2.8 2 1 1 3 3 3 0 NTPase TIP49_C PF17856.1 KFR06269.1 - 0.092 12.9 0.1 0.35 11.0 0.1 2.0 1 0 0 1 1 1 0 TIP49 AAA-lid domain AAA_22 PF13401.6 KFR06269.1 - 0.16 12.3 0.9 11 6.3 0.0 3.0 2 1 1 3 3 3 0 AAA domain CRISPR_Cse2 PF09485.10 KFR06269.1 - 0.36 11.3 1.9 2.3 8.8 2.0 2.3 1 1 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DUF4503 PF14951.6 KFR06270.1 - 3.1e-171 569.2 8.6 3.1e-171 569.2 8.6 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4503) DUF4502 PF14950.6 KFR06270.1 - 1e-51 176.6 0.3 1.6e-51 175.9 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4502) DUF4502 PF14950.6 KFR06271.1 - 3.9e-40 138.5 22.3 4.4e-40 138.3 22.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4502) CDP-OH_P_transf PF01066.21 KFR06272.1 - 5.3e-16 59.1 0.3 5.3e-16 59.1 0.3 3.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase EB1 PF03271.17 KFR06273.1 - 2.6e-16 59.6 0.3 8.4e-16 57.9 0.2 2.0 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.31 KFR06273.1 - 3.8e-13 49.6 0.3 6e-13 48.9 0.3 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFR06273.1 - 0.0015 18.3 0.1 0.0035 17.1 0.1 1.6 1 0 0 1 1 1 1 CAMSAP CH domain MIS13 PF08202.11 KFR06273.1 - 0.031 13.6 0.1 0.044 13.1 0.1 1.2 1 0 0 1 1 1 0 Mis12-Mtw1 protein family EF-hand_2 PF09068.11 KFR06274.1 - 8.4e-35 119.6 1.6 2.5e-34 118.0 0.8 2.2 2 0 0 2 2 2 1 EF hand EF-hand_3 PF09069.11 KFR06274.1 - 3e-30 104.5 0.1 1.6e-29 102.1 0.0 2.3 2 0 0 2 2 2 1 EF-hand ZZ PF00569.17 KFR06274.1 - 2.9e-09 36.6 9.7 2.9e-09 36.6 9.7 1.6 2 0 0 2 2 2 1 Zinc finger, ZZ type C1_2 PF03107.16 KFR06274.1 - 0.0017 18.6 7.4 0.0036 17.6 7.4 1.5 1 0 0 1 1 1 1 C1 domain Seryl_tRNA_N PF02403.22 KFR06274.1 - 0.02 15.1 8.1 0.08 13.2 8.1 2.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain SOGA PF11365.8 KFR06274.1 - 0.095 13.8 9.4 0.08 14.1 6.7 2.5 2 0 0 2 2 2 0 Protein SOGA FapA PF03961.13 KFR06274.1 - 0.35 9.4 5.4 0.64 8.6 5.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A MerR-DNA-bind PF09278.11 KFR06274.1 - 2.2 8.8 11.9 3 8.5 10.1 2.2 1 1 1 2 2 2 0 MerR, DNA binding CEBP_ZZ PF16366.5 KFR06274.1 - 3.7 7.9 12.2 7.9 6.8 12.2 1.5 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Integrase_H2C2 PF17921.1 KFR06277.1 - 0.00019 21.5 3.5 0.0011 19.0 0.2 2.5 2 1 0 2 2 2 1 Integrase zinc binding domain BEN PF10523.9 KFR06277.1 - 0.008 16.4 0.3 0.29 11.4 0.0 2.8 2 0 0 2 2 2 1 BEN domain ASXH PF13919.6 KFR06278.1 - 8.2e-35 119.8 1.8 1.6e-34 118.9 0.2 2.4 2 0 0 2 2 2 1 Asx homology domain PHD_3 PF13922.6 KFR06278.1 - 1.3e-20 73.5 8.0 1.3e-20 73.5 8.0 3.0 2 0 0 2 2 2 1 PHD domain of transcriptional enhancer, Asx HARE-HTH PF05066.13 KFR06278.1 - 0.00023 21.5 0.0 0.00054 20.3 0.0 1.7 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain PRIMA1 PF16101.5 KFR06278.1 - 0.39 10.7 8.1 2 8.5 8.1 2.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF1284 PF06935.11 KFR06278.1 - 1.4 9.4 8.1 0.064 13.7 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1284) PhaP_Bmeg PF09602.10 KFR06278.1 - 5.7 6.8 10.9 0.33 10.9 0.5 3.3 3 0 0 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Ras PF00071.22 KFR06279.1 - 4e-45 153.3 0.0 4.7e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR06279.1 - 3.2e-20 72.5 0.1 5.3e-20 71.8 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR06279.1 - 2.3e-09 37.0 0.1 2.9e-09 36.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFR06279.1 - 0.00014 21.5 0.0 0.00024 20.7 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFR06279.1 - 0.0036 16.7 0.1 0.006 16.0 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region CABIT PF12736.7 KFR06280.1 - 9.8e-55 185.8 0.7 1.5e-54 185.2 0.7 1.3 1 0 0 1 1 1 1 Cell-cycle sustaining, positive selection, SAM_1 PF00536.30 KFR06280.1 - 0.0027 18.1 0.1 0.0049 17.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Astacin PF01400.24 KFR06281.1 - 3.6e-72 242.0 0.2 6.5e-72 241.2 0.2 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MAM PF00629.23 KFR06281.1 - 3.8e-40 137.4 0.0 4.7e-39 133.9 0.0 2.2 2 0 0 2 2 2 1 MAM domain, meprin/A5/mu EGF PF00008.27 KFR06281.1 - 1.2e-05 25.5 2.9 3.4e-05 24.0 2.9 1.9 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 KFR06281.1 - 0.019 15.6 4.4 0.07 13.8 4.4 2.1 1 0 0 1 1 1 0 Human growth factor-like EGF DAG1 PF05454.11 KFR06281.1 - 0.03 13.7 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) EGF_2 PF07974.13 KFR06281.1 - 0.94 9.9 5.4 3.3 8.2 5.4 2.0 1 0 0 1 1 1 0 EGF-like domain zf_C2HC_14 PF18574.1 KFR06282.1 - 8.6e-18 63.8 6.8 8.6e-18 63.8 6.8 2.5 3 0 0 3 3 3 1 C2HC Zing finger domain zf-Di19 PF05605.12 KFR06282.1 - 2e-13 50.4 8.2 2e-13 50.4 8.2 3.4 4 1 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_2 PF13923.6 KFR06282.1 - 8.6e-11 41.5 8.9 8.6e-11 41.5 8.9 3.8 3 2 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFR06282.1 - 7.1e-10 38.7 6.9 7.1e-10 38.7 6.9 3.5 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFR06282.1 - 1.3e-09 38.0 6.7 1.3e-09 38.0 6.7 4.7 3 2 1 4 4 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KFR06282.1 - 9.3e-09 35.0 8.8 9.3e-09 35.0 8.8 4.2 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFR06282.1 - 2.6e-08 34.1 9.7 2.6e-08 34.1 9.7 4.1 3 1 0 3 3 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFR06282.1 - 6.2e-08 32.4 6.6 6.2e-08 32.4 6.6 4.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFR06282.1 - 1.9e-07 30.9 8.1 1.9e-07 30.9 8.1 4.0 3 1 0 3 3 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFR06282.1 - 6e-07 29.2 7.7 6e-07 29.2 7.7 3.8 3 1 1 4 4 4 2 Prokaryotic RING finger family 4 U-box PF04564.15 KFR06282.1 - 0.0021 18.2 0.0 0.0046 17.1 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-RING_6 PF14835.6 KFR06282.1 - 0.011 15.6 5.6 0.011 15.6 5.6 2.4 2 1 0 2 2 2 0 zf-RING of BARD1-type protein Glyco_transf_7N PF13733.6 KFR06285.1 - 8e-55 184.1 0.0 1.3e-54 183.5 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 KFR06285.1 - 3.8e-28 96.9 0.7 6.8e-28 96.1 0.7 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Transthyretin PF00576.21 KFR06286.1 - 1e-22 80.9 0.0 1.3e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family TTR-52 PF01060.23 KFR06286.1 - 0.029 15.1 0.0 0.044 14.5 0.0 1.2 1 0 0 1 1 1 0 Transthyretin-like family Transthyretin PF00576.21 KFR06287.1 - 4.1e-21 75.7 0.1 5.2e-21 75.4 0.1 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family Lipase_C PF18067.1 KFR06287.1 - 0.063 13.8 0.0 0.094 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipase C-terminal domain Cadherin PF00028.17 KFR06288.1 - 1.1e-58 195.7 3.9 3e-20 72.5 0.0 5.4 5 0 0 5 5 5 5 Cadherin domain Cadherin_2 PF08266.12 KFR06288.1 - 1.4e-05 24.8 0.0 0.16 11.8 0.0 3.7 3 0 0 3 3 3 2 Cadherin-like Cadherin_3 PF16184.5 KFR06288.1 - 6.3e-05 22.9 1.4 1 9.4 0.0 3.8 3 0 0 3 3 3 2 Cadherin-like Cadherin_C PF01049.17 KFR06288.1 - 0.00038 20.8 0.0 0.00085 19.7 0.0 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region RET_CLD1 PF17756.1 KFR06288.1 - 0.14 12.5 0.0 3.3 8.0 0.0 2.6 3 0 0 3 3 3 0 RET Cadherin like domain 1 Cadherin PF00028.17 KFR06290.1 - 3.9e-54 181.1 0.1 9.2e-16 58.1 0.0 4.3 4 0 0 4 4 4 4 Cadherin domain Cadherin_C PF01049.17 KFR06290.1 - 1.8e-06 28.4 0.0 3.8e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.12 KFR06290.1 - 0.00013 21.7 0.0 4 7.3 0.0 3.4 3 0 0 3 3 3 2 Cadherin-like RET_CLD1 PF17756.1 KFR06290.1 - 0.00047 20.4 0.0 0.018 15.3 0.0 2.7 2 1 1 3 3 3 1 RET Cadherin like domain 1 RRM_1 PF00076.22 KFR06347.1 - 2.2e-36 123.5 0.4 2.6e-17 62.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFR06347.1 - 9.1e-18 64.2 1.2 4.2e-08 33.2 0.1 2.6 2 1 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 KFR06347.1 - 4.2e-07 30.0 0.5 0.0074 16.3 0.1 2.6 2 1 0 2 2 2 2 RNA binding motif NID PF07292.13 KFR06347.1 - 0.00036 21.1 0.5 0.012 16.2 0.0 2.5 2 1 0 2 2 2 1 Nmi/IFP 35 domain (NID) Nup35_RRM_2 PF14605.6 KFR06347.1 - 0.00095 19.1 0.0 0.12 12.5 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DUF2076 PF09849.9 KFR06347.1 - 2 8.4 6.0 2.9 7.9 6.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) RRM_1 PF00076.22 KFR06348.1 - 2.7e-34 116.8 0.1 2.5e-16 59.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFR06348.1 - 1.9e-18 66.4 0.1 8.1e-10 38.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KFR06348.1 - 9e-05 22.4 0.0 0.017 15.1 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KFR06348.1 - 0.00023 21.2 0.2 0.048 13.7 0.1 2.7 2 2 0 2 2 2 2 RNA binding motif RL PF17797.1 KFR06348.1 - 0.039 13.9 0.0 5.2 7.1 0.0 2.6 2 1 0 2 2 2 0 RL domain Hydrolase PF00702.26 KFR06349.1 - 0.0029 17.9 0.0 0.0033 17.8 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFR06349.1 - 0.041 14.0 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Frag1 PF10277.9 KFR06350.1 - 3.9e-44 150.8 6.2 4.5e-44 150.6 6.2 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.13 KFR06350.1 - 0.0044 16.6 5.5 0.0044 16.6 5.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF998) FA_desaturase PF00487.24 KFR06351.1 - 1.1e-17 64.8 12.4 1.4e-17 64.4 12.4 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Sec16_C PF12931.7 KFR06352.1 - 1.7e-05 24.6 1.6 9.6e-05 22.2 1.6 2.1 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 SRA1 PF07304.11 KFR06352.1 - 0.00028 20.7 0.0 0.00083 19.2 0.0 1.8 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.15 KFR06352.1 - 0.0049 16.9 0.6 0.015 15.4 0.0 1.9 2 0 0 2 2 2 1 Prp18 domain WD40 PF00400.32 KFR06352.1 - 0.0061 17.4 4.0 58 4.8 0.0 5.9 6 0 0 6 6 6 0 WD domain, G-beta repeat Tnp_P_element PF12017.8 KFR06353.1 - 2.8e-13 49.8 0.0 4.3e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Transposase protein TCR PF03638.15 KFR06354.1 - 1.6e-22 79.5 59.0 8.9e-13 48.3 22.9 2.7 3 0 0 3 3 3 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 KFR06354.1 - 0.11 12.6 45.0 0.35 11.0 17.1 2.7 2 0 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 CSN4_RPN5_eIF3a PF18420.1 KFR06355.1 - 3e-25 88.1 3.7 8.3e-25 86.7 3.7 1.8 1 0 0 1 1 1 1 CSN4/RPN5/eIF3a helix turn helix domain PCI PF01399.27 KFR06355.1 - 3.4e-18 66.1 2.9 9.4e-18 64.7 0.0 2.7 3 1 1 4 4 4 1 PCI domain RPN7 PF10602.9 KFR06355.1 - 0.0038 17.0 1.1 0.0069 16.1 1.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_12 PF13424.6 KFR06355.1 - 0.015 15.6 1.1 0.9 9.9 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFR06355.1 - 0.031 14.3 1.1 3.2 8.0 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFR06355.1 - 0.095 13.0 0.4 3 8.3 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFR06355.1 - 1.2 10.1 5.0 3.2 8.8 0.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat YabA PF06156.13 KFR06355.1 - 2.2 9.0 7.6 11 6.7 0.1 3.5 3 1 1 4 4 4 0 Initiation control protein YabA RhoGAP PF00620.27 KFR06356.1 - 1.1e-49 168.1 0.0 3e-49 166.7 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain FPP PF05911.11 KFR06356.1 - 0.00029 19.2 9.5 0.00047 18.5 9.5 1.2 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil ATG16 PF08614.11 KFR06356.1 - 0.00049 20.4 8.1 0.0014 18.9 8.1 1.7 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) PH PF00169.29 KFR06356.1 - 0.00057 20.4 2.4 0.0015 19.0 0.1 2.7 3 0 0 3 3 3 1 PH domain ADIP PF11559.8 KFR06356.1 - 0.081 13.0 9.8 0.25 11.4 9.8 1.8 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3435 PF11917.8 KFR06356.1 - 0.091 11.7 5.3 0.14 11.0 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DMPK_coil PF08826.10 KFR06356.1 - 2.1 8.5 16.1 4.3 7.5 7.0 3.0 1 1 1 2 2 2 0 DMPK coiled coil domain like bZIP_1 PF00170.21 KFR06356.1 - 4.2 7.5 13.4 0.93 9.6 3.9 3.8 2 1 2 4 4 4 0 bZIP transcription factor Pkinase PF00069.25 KFR06357.1 - 2.8e-65 220.3 0.0 3.6e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR06357.1 - 4e-31 108.3 0.1 5.4e-31 107.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFR06357.1 - 1.9e-07 30.7 0.2 2.9e-07 30.1 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFR06357.1 - 6.1e-05 22.5 0.0 0.00013 21.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFR06357.1 - 0.00033 20.3 0.2 0.0006 19.5 0.2 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KFR06357.1 - 0.00063 19.7 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KFR06357.1 - 0.069 12.8 0.1 0.14 11.8 0.1 1.7 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KFR06357.1 - 0.094 11.6 0.7 0.22 10.4 0.7 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Y_phosphatase PF00102.27 KFR06358.1 - 1.8e-75 253.6 0.0 2.2e-75 253.3 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFR06358.1 - 0.00019 21.2 0.0 0.00031 20.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFR06358.1 - 0.0019 18.4 0.0 0.0046 17.1 0.0 1.6 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KFR06358.1 - 0.085 12.8 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Kelch_1 PF01344.25 KFR06359.1 - 3.1e-75 247.6 15.5 1.1e-15 56.9 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFR06359.1 - 1.4e-42 142.6 5.6 2.4e-08 34.0 0.0 6.4 3 2 3 6 6 6 6 Kelch motif Kelch_2 PF07646.15 KFR06359.1 - 9.9e-30 101.4 9.3 4.2e-05 23.3 0.0 6.5 6 0 0 6 6 6 6 Kelch motif BACK PF07707.15 KFR06359.1 - 1.6e-28 98.8 0.7 1.6e-28 98.8 0.7 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 KFR06359.1 - 8.9e-26 89.6 9.2 9.9e-05 22.5 0.2 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain BTB PF00651.31 KFR06359.1 - 2.2e-24 85.8 2.9 2.2e-24 85.8 1.2 1.9 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.6 KFR06359.1 - 2e-23 82.1 7.5 9.1e-05 22.4 0.0 6.6 5 2 2 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KFR06359.1 - 1.6e-05 24.7 8.3 1.9 8.5 0.0 5.4 5 0 0 5 5 5 3 Kelch motif Trypsin PF00089.26 KFR06372.1 - 1.4e-27 96.9 0.3 1.5e-27 96.8 0.3 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFR06372.1 - 0.0048 17.3 0.5 0.0059 17.0 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Latrophilin PF02354.16 KFR06375.1 - 3.2e-152 507.0 14.3 5e-152 506.3 14.3 1.2 1 0 0 1 1 1 1 Latrophilin Cytoplasmic C-terminal region OLF PF02191.16 KFR06375.1 - 4.1e-85 285.3 5.2 8.1e-85 284.3 5.2 1.5 1 0 0 1 1 1 1 Olfactomedin-like domain 7tm_2 PF00002.24 KFR06375.1 - 7.5e-70 235.0 19.3 1.1e-69 234.4 19.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GAIN PF16489.5 KFR06375.1 - 1.2e-53 181.7 4.7 1.9e-53 181.1 4.7 1.3 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Gal_Lectin PF02140.18 KFR06375.1 - 4.7e-23 81.4 0.7 4.7e-23 81.4 0.7 2.1 2 0 0 2 2 2 1 Galactose binding lectin domain GPS PF01825.21 KFR06375.1 - 7.5e-16 58.4 6.2 1.8e-15 57.2 6.2 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif HRM PF02793.22 KFR06375.1 - 1.7e-07 31.4 2.6 3.2e-07 30.5 0.7 2.4 2 0 0 2 2 2 1 Hormone receptor domain Dicty_CAR PF05462.11 KFR06375.1 - 0.00029 20.1 10.5 0.00063 19.0 10.5 1.5 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Pox_A14 PF05767.12 KFR06375.1 - 3.6 7.8 6.4 4.2 7.6 2.1 2.8 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 C1-set PF07654.15 KFR06376.1 - 2.4e-18 66.3 0.0 3.5e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.6 KFR06376.1 - 1.7e-05 25.3 0.2 2.9e-05 24.6 0.2 1.4 1 1 0 1 1 1 1 Immunoglobulin domain MHC_II_beta PF00969.19 KFR06376.1 - 0.00018 21.5 0.0 0.00026 21.0 0.0 1.3 1 0 0 1 1 1 1 Class II histocompatibility antigen, beta domain Ig_2 PF13895.6 KFR06376.1 - 0.0021 18.4 0.0 0.0035 17.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFR06376.1 - 0.0039 17.3 0.0 0.0064 16.6 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 KFR06376.1 - 0.021 14.9 0.1 0.071 13.2 0.1 1.7 1 1 0 1 1 1 0 CD80-like C2-set immunoglobulin domain 7tm_1 PF00001.21 KFR06377.1 - 1.6e-19 70.3 3.5 1.9e-19 70.0 3.5 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RRM_1 PF00076.22 KFR06379.1 - 6.2e-68 224.6 0.1 1.5e-21 76.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFR06379.1 - 1.1e-12 47.7 0.0 0.00013 21.6 0.0 3.1 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFR06379.1 - 8.6e-05 22.3 0.0 0.26 11.1 0.0 3.4 3 1 0 3 3 3 1 Occluded RNA-recognition motif BRAP2 PF07576.12 KFR06379.1 - 9.6e-05 22.5 0.0 0.72 10.1 0.0 2.8 3 0 0 3 3 3 2 BRCA1-associated protein 2 RRM_7 PF16367.5 KFR06379.1 - 0.0005 20.1 0.0 1.1 9.5 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif RRM_3 PF08777.11 KFR06379.1 - 0.00062 19.8 0.0 0.5 10.5 0.0 2.5 2 0 0 2 2 2 2 RNA binding motif RRM_2 PF04059.12 KFR06379.1 - 0.071 13.3 0.1 0.51 10.6 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif 2 RNA_bind PF08675.11 KFR06379.1 - 0.11 12.5 0.0 2.8 8.0 0.0 2.7 2 1 0 2 2 2 0 RNA binding domain zf-C3HC4_2 PF13923.6 KFR06380.1 - 1.3e-10 40.9 7.9 1.3e-10 40.9 7.9 2.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFR06380.1 - 1.3e-09 37.8 5.5 1.3e-09 37.8 5.5 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFR06380.1 - 3.8e-09 36.3 7.1 3.8e-09 36.3 7.1 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFR06380.1 - 1e-08 35.4 9.0 1e-08 35.4 9.0 2.7 3 0 0 3 3 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KFR06380.1 - 3e-07 30.3 1.8 3e-07 30.3 1.8 3.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 KFR06380.1 - 1e-05 25.7 5.5 5.5e-05 23.4 5.5 2.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFR06380.1 - 2.1e-05 24.4 8.2 2.1e-05 24.4 8.2 2.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFR06380.1 - 3.3e-05 24.0 7.7 3.3e-05 24.0 7.7 2.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFR06380.1 - 0.0013 18.6 9.9 0.02 14.7 9.5 2.8 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFR06380.1 - 0.0047 16.9 3.1 0.013 15.5 3.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 KFR06380.1 - 0.14 12.3 2.5 2.4 8.4 3.8 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KFR06380.1 - 1.7 8.5 14.8 0.5 10.2 9.4 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain TMEM215 PF15746.5 KFR06381.1 - 1.2e-120 401.0 1.1 1.4e-120 400.8 1.1 1.0 1 0 0 1 1 1 1 TMEM215 family Guanylate_cyc PF00211.20 KFR06382.1 - 3.5e-65 219.0 0.3 2.7e-64 216.1 0.0 2.1 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 KFR06382.1 - 8.9e-43 146.4 0.0 1.4e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR06382.1 - 9e-34 117.0 0.0 1.6e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 KFR06382.1 - 1.5e-06 27.8 1.5 2.4e-06 27.1 1.5 1.3 1 0 0 1 1 1 1 Heme NO binding associated 7tm_1 PF00001.21 KFR06383.1 - 6e-31 107.7 24.2 1.8e-30 106.2 24.0 1.7 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Pkinase_Tyr PF07714.17 KFR06384.1 - 5.4e-94 314.3 0.0 7.4e-94 313.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase I-set PF07679.16 KFR06384.1 - 2.4e-47 158.9 0.0 2.3e-19 69.2 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR06384.1 - 2.5e-40 137.0 0.3 1.9e-14 54.0 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Pkinase PF00069.25 KFR06384.1 - 5e-40 137.5 0.0 1.1e-39 136.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Ig_2 PF13895.6 KFR06384.1 - 1e-27 96.3 0.1 1.6e-09 37.9 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin domain Kringle PF00051.18 KFR06384.1 - 9.2e-25 86.8 6.0 2.1e-24 85.6 6.0 1.7 1 0 0 1 1 1 1 Kringle domain ig PF00047.25 KFR06384.1 - 9.2e-21 73.8 0.1 3.7e-09 36.6 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Fz PF01392.22 KFR06384.1 - 8.1e-16 58.6 3.5 2.2e-15 57.2 3.5 1.8 1 0 0 1 1 1 1 Fz domain C2-set_2 PF08205.12 KFR06384.1 - 1.8e-11 43.9 0.1 0.0076 16.3 0.0 3.7 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFR06384.1 - 1.6e-07 31.4 3.5 0.11 12.7 0.0 5.0 4 2 1 5 5 4 2 Immunoglobulin V-set domain Ig_6 PF18452.1 KFR06384.1 - 2e-05 24.1 0.0 0.24 11.0 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.15 KFR06384.1 - 0.00067 20.0 0.1 0.28 11.6 0.0 2.8 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Ig_4 PF16680.5 KFR06384.1 - 0.0022 18.2 0.1 1.7 9.0 0.0 3.9 4 0 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFR06384.1 - 0.013 15.5 0.1 0.67 10.0 0.0 2.7 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Herpes_gE PF02480.16 KFR06384.1 - 0.015 14.1 0.0 0.24 10.1 0.0 2.4 2 1 1 3 3 3 0 Alphaherpesvirus glycoprotein E Haspin_kinase PF12330.8 KFR06384.1 - 0.022 13.7 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain CD34_antigen PF06365.12 KFR06384.1 - 0.045 13.3 0.2 0.077 12.6 0.2 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family DAG1 PF05454.11 KFR06384.1 - 0.074 12.4 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Ig_C17orf99 PF17736.1 KFR06384.1 - 0.081 13.0 0.3 16 5.6 0.0 3.0 3 0 0 3 3 3 0 C17orf99 Ig domain EphA2_TM PF14575.6 KFR06384.1 - 0.11 13.4 0.0 0.22 12.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR1 PF02440.15 KFR06384.1 - 0.13 12.1 0.1 4.5 7.1 0.0 2.9 3 0 0 3 3 3 0 Adenovirus E3 region protein CR1 Adeno_E3_CR2 PF02439.15 KFR06384.1 - 0.15 11.9 1.2 0.29 10.9 1.2 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Sterol-sensing PF12349.8 KFR06384.1 - 1.2 9.0 3.0 10 5.9 0.0 2.3 2 0 0 2 2 2 0 Sterol-sensing domain of SREBP cleavage-activation Thioredoxin PF00085.20 KFR06385.1 - 8.1e-30 102.9 1.6 8.8e-30 102.7 1.6 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KFR06385.1 - 1.3e-05 25.4 0.2 1.9e-05 24.9 0.2 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KFR06385.1 - 7.5e-05 23.1 0.6 0.00022 21.6 0.6 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFR06385.1 - 0.00057 20.0 0.2 0.00088 19.4 0.2 1.4 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KFR06385.1 - 0.0013 18.6 0.4 0.0018 18.2 0.4 1.3 1 1 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 KFR06385.1 - 0.0017 17.8 0.4 0.0019 17.6 0.4 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DIM1 PF02966.16 KFR06385.1 - 0.0042 16.8 0.2 0.0044 16.8 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Glutaredoxin PF00462.24 KFR06385.1 - 0.0043 17.2 0.8 0.0075 16.5 0.8 1.5 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.6 KFR06385.1 - 0.02 14.7 0.2 0.024 14.4 0.2 1.3 1 1 0 1 1 1 0 Thioredoxin ADH_N_2 PF16884.5 KFR06386.1 - 2.5e-36 123.8 0.0 4.7e-36 123.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KFR06386.1 - 6.7e-23 81.1 0.0 1e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFR06386.1 - 8.2e-11 43.1 0.0 1.7e-10 42.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ecm29 PF13001.7 KFR06387.1 - 1.4e-147 492.3 0.8 1.4e-147 492.3 0.8 4.0 5 0 0 5 5 5 1 Proteasome stabiliser HEAT_2 PF13646.6 KFR06387.1 - 4.2e-13 49.5 1.3 0.96 9.9 0.0 8.5 6 1 2 8 8 8 4 HEAT repeats Vac14_Fab1_bd PF12755.7 KFR06387.1 - 2e-11 44.3 0.5 0.0011 19.6 0.1 7.8 7 1 1 8 8 7 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KFR06387.1 - 1.5e-10 40.4 14.2 1.5 9.3 0.0 12.4 14 0 0 14 14 12 2 HEAT repeat HEAT_EZ PF13513.6 KFR06387.1 - 1.7e-09 38.0 10.1 3.3 8.3 0.1 10.5 10 1 1 11 11 10 1 HEAT-like repeat IFRD PF05004.13 KFR06387.1 - 2.3e-06 26.9 19.7 0.022 13.9 0.0 6.4 6 0 0 6 6 6 4 Interferon-related developmental regulator (IFRD) Adaptin_N PF01602.20 KFR06387.1 - 5.7e-06 25.2 8.0 0.016 13.8 0.8 5.6 4 2 0 4 4 4 2 Adaptin N terminal region Catalase-rel PF06628.12 KFR06387.1 - 0.11 12.7 0.2 6.4 7.1 0.0 3.5 3 0 0 3 3 3 0 Catalase-related immune-responsive CLASP_N PF12348.8 KFR06387.1 - 0.17 11.4 13.9 0.11 12.1 0.2 5.3 6 1 1 7 7 7 0 CLASP N terminal PUL PF08324.11 KFR06387.1 - 0.41 9.8 3.9 1 8.6 0.0 3.5 4 0 0 4 4 4 0 PUL domain RTP1_C1 PF10363.9 KFR06387.1 - 1.1 9.5 8.6 15 5.8 0.1 5.4 6 0 0 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 L31 PF09784.9 KFR06388.1 - 0.036 14.5 2.1 0.11 13.0 2.1 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 G-gamma PF00631.22 KFR06389.1 - 1e-09 38.2 0.0 1.1e-09 38.2 0.0 1.0 1 0 0 1 1 1 1 GGL domain DUF4462 PF14692.6 KFR06390.1 - 0.17 11.3 0.0 0.36 10.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Glyco_transf_21 PF13506.6 KFR06391.1 - 1.1e-59 200.8 0.0 1.5e-59 200.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KFR06391.1 - 5.7e-24 85.3 0.0 6.9e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KFR06391.1 - 1e-12 48.4 5.1 1.3e-12 48.0 5.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KFR06391.1 - 0.00037 20.3 0.0 0.00083 19.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 RRM_5 PF13893.6 KFR06392.1 - 3.6e-55 184.9 0.3 2e-42 143.8 0.0 4.1 3 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KFR06392.1 - 8e-30 102.5 0.7 8.4e-10 38.3 0.0 4.9 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KFR06392.1 - 1.2e-13 51.1 0.0 1.2e-12 47.8 0.0 2.3 2 0 0 2 2 2 1 RRM-like domain RRM_occluded PF16842.5 KFR06392.1 - 6.9e-08 32.2 0.2 0.81 9.6 0.0 4.2 4 0 0 4 4 4 3 Occluded RNA-recognition motif Cys_Met_Meta_PP PF01053.20 KFR06392.1 - 0.014 14.0 0.0 0.02 13.4 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme BRAP2 PF07576.12 KFR06392.1 - 0.073 13.3 0.1 9 6.6 0.0 3.5 4 0 0 4 4 4 0 BRCA1-associated protein 2 adh_short PF00106.25 KFR06393.1 - 3.5e-33 114.7 0.2 6e-33 113.9 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFR06393.1 - 6.9e-27 94.5 0.5 1.1e-26 93.9 0.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SCP2 PF02036.17 KFR06393.1 - 1.6e-22 79.9 0.1 3.1e-22 79.0 0.1 1.4 1 0 0 1 1 1 1 SCP-2 sterol transfer family KR PF08659.10 KFR06393.1 - 0.00049 20.1 0.2 0.001 19.1 0.2 1.5 1 0 0 1 1 1 1 KR domain Alkyl_sulf_C PF14864.6 KFR06393.1 - 0.039 14.2 0.0 0.077 13.3 0.0 1.4 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal DUF3504 PF12012.8 KFR06394.1 - 2e-11 44.1 3.2 2.2e-11 43.9 1.1 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3504) Phage_int_SAM_5 PF13102.6 KFR06394.1 - 0.0021 18.4 0.8 0.0041 17.4 0.3 1.8 2 0 0 2 2 2 1 Phage integrase SAM-like domain Phage_int_SAM_4 PF13495.6 KFR06394.1 - 0.06 13.8 0.3 0.25 11.8 0.1 2.1 1 1 1 2 2 2 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.17 KFR06394.1 - 0.061 13.6 0.4 15 6.0 0.1 2.7 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain WIF PF02019.18 KFR06394.1 - 0.097 12.4 0.1 1 9.1 0.1 2.2 2 0 0 2 2 2 0 WIF domain SOSSC PF15925.5 KFR06395.1 - 5e-23 82.3 0.8 3.5e-22 79.6 0.8 1.9 1 1 0 1 1 1 1 SOSS complex subunit C PX PF00787.24 KFR06396.1 - 6.5e-24 84.1 1.8 1.3e-23 83.1 1.8 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KFR06396.1 - 1.7e-09 37.6 2.2 8.4e-05 22.2 0.0 2.5 2 1 1 3 3 3 2 Vps5 C terminal like BAR PF03114.18 KFR06396.1 - 9.6e-08 32.0 0.3 9.6e-08 32.0 0.3 1.6 2 0 0 2 2 2 1 BAR domain BAR_3_WASP_bdg PF10456.9 KFR06396.1 - 0.0032 17.0 0.1 0.0071 15.8 0.1 1.5 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein MFS_1 PF07690.16 KFR06397.1 - 2.5e-08 33.2 35.0 2.5e-08 33.2 35.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily AKAP2_C PF15304.6 KFR06398.1 - 2.7e-15 56.5 14.6 2.7e-15 56.5 14.6 3.0 2 1 0 2 2 2 1 A-kinase anchor protein 2 C-terminus Misat_Tub_SegII PF10644.9 KFR06398.1 - 0.2 12.0 0.0 0.2 12.0 0.0 2.6 3 0 0 3 3 3 0 Misato Segment II tubulin-like domain Paralemmin PF03285.15 KFR06399.1 - 2e-97 326.6 15.6 2.4e-97 326.3 15.6 1.0 1 0 0 1 1 1 1 Paralemmin Exonuc_VII_L PF02601.15 KFR06399.1 - 0.035 13.7 1.7 0.037 13.6 0.7 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF1843 PF08898.10 KFR06399.1 - 0.37 11.3 2.1 2.8 8.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) TMPIT PF07851.13 KFR06399.1 - 6.7 5.9 6.2 10 5.3 6.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein PAP2 PF01569.21 KFR06400.1 - 1.1e-20 73.8 1.1 2.1e-20 72.9 1.1 1.4 1 0 0 1 1 1 1 PAP2 superfamily Ribosomal_L50 PF10501.9 KFR06401.1 - 3.9e-10 39.8 0.0 5.2e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal subunit 39S zf-C3HC4_3 PF13920.6 KFR06403.1 - 1.3e-06 28.2 11.6 2.2e-06 27.4 11.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFR06403.1 - 7.1e-05 22.6 14.6 0.00013 21.7 14.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFR06403.1 - 0.00022 21.0 14.6 0.0004 20.2 14.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFR06403.1 - 0.00033 20.5 13.6 0.0016 18.4 14.0 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFR06403.1 - 0.0016 18.7 13.3 0.0028 17.9 13.3 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KFR06403.1 - 0.0081 16.0 9.2 0.015 15.1 9.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFR06403.1 - 0.012 15.8 8.0 0.028 14.7 8.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFR06403.1 - 0.019 15.0 10.4 0.039 14.0 10.4 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 KFR06403.1 - 0.59 10.2 4.8 1.1 9.4 4.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KFR06403.1 - 1.7 8.9 10.0 4.8 7.4 10.1 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Lig_chan PF00060.26 KFR06404.1 - 1.1e-29 103.2 0.2 4.2e-29 101.3 0.0 2.0 2 0 0 2 2 2 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFR06404.1 - 5.8e-27 94.2 0.0 4.4e-26 91.3 0.0 2.2 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFR06404.1 - 6.2e-20 71.6 0.0 1e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 KFR06404.1 - 2.6e-07 30.1 0.2 9.1e-05 21.7 0.2 2.2 1 1 0 1 1 1 1 Receptor family ligand binding region JIP_LZII PF16471.5 KFR06404.1 - 0.054 13.7 3.0 0.15 12.3 3.0 1.6 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II Pkinase PF00069.25 KFR06444.1 - 8.5e-69 231.8 0.0 1.2e-68 231.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR06444.1 - 2.4e-37 128.6 0.0 3.7e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KFR06444.1 - 5.5e-13 49.4 0.0 1.9e-12 47.6 0.0 2.0 2 0 0 2 2 2 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 KFR06444.1 - 1.2e-05 24.7 0.0 2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFR06444.1 - 0.0053 16.4 0.1 0.0095 15.5 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KFR06444.1 - 0.0075 15.6 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family G2F PF07474.12 KFR06451.1 - 1.1e-71 240.5 0.2 2.2e-71 239.5 0.2 1.5 1 0 0 1 1 1 1 G2F domain Ldl_recept_b PF00058.17 KFR06451.1 - 3.3e-36 123.5 3.6 4.1e-10 40.0 0.1 4.7 4 0 0 4 4 4 3 Low-density lipoprotein receptor repeat class B EGF_3 PF12947.7 KFR06451.1 - 5.7e-30 103.2 102.4 3.1e-09 36.9 9.5 6.5 6 0 0 6 6 6 5 EGF domain NIDO PF06119.14 KFR06451.1 - 2.1e-22 79.8 0.7 7.6e-22 78.1 0.7 2.1 1 0 0 1 1 1 1 Nidogen-like EGF_CA PF07645.15 KFR06451.1 - 8.4e-20 70.7 94.5 3.3e-09 36.8 8.6 6.9 6 0 0 6 6 5 5 Calcium-binding EGF domain cEGF PF12662.7 KFR06451.1 - 9.2e-19 67.1 51.1 3.7e-07 29.9 1.4 6.6 6 0 0 6 6 6 5 Complement Clr-like EGF-like Thyroglobulin_1 PF00086.18 KFR06451.1 - 1.2e-18 66.5 1.8 5.9e-18 64.3 1.8 2.3 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat FXa_inhibition PF14670.6 KFR06451.1 - 1.7e-17 63.4 87.8 2.8e-08 33.9 7.1 6.5 5 1 1 6 6 6 5 Coagulation Factor Xa inhibitory site EGF PF00008.27 KFR06451.1 - 4.9e-11 42.7 93.7 0.0062 16.8 6.3 7.0 7 0 0 7 7 7 6 EGF-like domain EGF_MSP1_1 PF12946.7 KFR06451.1 - 2.4e-05 24.3 67.7 0.00081 19.4 1.8 5.8 6 0 0 6 6 6 4 MSP1 EGF domain 1 SGL PF08450.12 KFR06451.1 - 2.8e-05 23.8 0.3 0.00022 20.9 0.1 2.9 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Beach PF02138.18 KFR06452.1 - 1.5e-110 368.9 0.4 2.6e-110 368.1 0.4 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KFR06452.1 - 1.2e-22 79.8 0.0 3.9e-22 78.2 0.0 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 KFR06452.1 - 2.6e-07 31.2 13.4 0.069 14.0 0.1 5.9 4 1 1 5 5 5 4 WD domain, G-beta repeat DUF4800 PF16057.5 KFR06452.1 - 0.064 12.5 2.9 0.18 11.0 2.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) G-gamma PF00631.22 KFR06453.1 - 1.3e-16 60.4 0.0 1.5e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 GGL domain Galactosyl_T PF01762.21 KFR06454.1 - 5.2e-27 94.9 0.0 5.3e-24 85.1 0.0 2.2 2 0 0 2 2 2 2 Galactosyltransferase Fringe PF02434.16 KFR06454.1 - 0.03 13.8 0.4 0.75 9.2 0.0 2.3 2 1 0 2 2 2 0 Fringe-like polyprenyl_synt PF00348.17 KFR06455.1 - 3.8e-62 209.6 0.0 5.4e-62 209.2 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase RBB1NT PF08169.11 KFR06456.1 - 1.4e-34 118.1 0.6 1.4e-34 118.1 0.6 2.8 2 0 0 2 2 2 1 RBB1NT (NUC162) domain ARID PF01388.21 KFR06456.1 - 1.4e-20 73.7 0.1 3.1e-20 72.6 0.1 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Tudor-knot PF11717.8 KFR06456.1 - 7.1e-12 45.0 0.3 2.7e-11 43.2 0.3 2.0 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Tudor_2 PF18104.1 KFR06456.1 - 2.8e-05 23.7 0.8 0.00015 21.3 0.2 2.4 2 0 0 2 2 2 1 Jumonji domain-containing protein 2A Tudor domain DUF4537 PF15057.6 KFR06456.1 - 0.027 14.5 0.1 9.3 6.3 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) RRM_1 PF00076.22 KFR06457.1 - 1.6e-30 104.7 0.3 4.6e-17 61.6 0.0 3.4 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFR06457.1 - 2.1e-10 40.6 0.1 0.00037 20.6 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif RRM_Rrp7 PF17799.1 KFR06457.1 - 6.2e-05 22.9 0.1 0.032 14.0 0.0 3.1 2 2 2 4 4 4 1 Rrp7 RRM-like N-terminal domain Spo7_2_N PF15407.6 KFR06457.1 - 0.0062 16.1 0.0 1.6 8.4 0.0 2.7 2 0 0 2 2 2 1 Sporulation protein family 7 Nup35_RRM PF05172.13 KFR06457.1 - 0.012 15.5 0.1 1.2 9.2 0.1 2.4 1 1 1 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.11 KFR06457.1 - 0.039 13.8 0.0 1 9.2 0.0 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF1866) Nup35_RRM_2 PF14605.6 KFR06457.1 - 0.1 12.7 0.0 2.5 8.2 0.0 2.5 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF1179 PF06678.11 KFR06457.1 - 1 9.4 8.1 0.19 11.8 4.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) Cellulose_synt PF03552.14 KFR06457.1 - 2 6.8 5.7 2.7 6.3 5.7 1.2 1 0 0 1 1 1 0 Cellulose synthase MAS20 PF02064.15 KFR06458.1 - 1.7e-27 96.0 0.4 2e-27 95.8 0.4 1.1 1 0 0 1 1 1 1 MAS20 protein import receptor RSN1_7TM PF02714.15 KFR06458.1 - 0.013 14.8 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 Calcium-dependent channel, 7TM region, putative phosphate TPR_1 PF00515.28 KFR06458.1 - 0.054 13.3 0.1 0.095 12.6 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFR06458.1 - 0.071 14.0 0.1 0.25 12.3 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFR06458.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat EamA PF00892.20 KFR06459.1 - 1.2e-07 32.0 8.7 1.2e-07 32.0 8.7 2.7 2 1 0 2 2 2 1 EamA-like transporter family SLC35F PF06027.12 KFR06459.1 - 1.9e-05 24.3 24.6 2.8e-05 23.8 24.6 1.2 1 0 0 1 1 1 1 Solute carrier family 35 zf-C3Hc3H PF13891.6 KFR06497.1 - 3.5e-15 56.1 7.5 5.3e-15 55.5 7.5 1.3 1 0 0 1 1 1 1 Potential DNA-binding domain Pox_A9 PF04835.12 KFR06497.1 - 0.16 12.1 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 A9 protein conserved region zf-C3Hc3H PF13891.6 KFR06498.1 - 2.4e-17 63.1 8.3 2.5e-17 63.0 5.3 2.1 2 0 0 2 2 2 1 Potential DNA-binding domain zf-TRM13_CCCH PF11722.8 KFR06498.1 - 0.0016 18.1 11.1 0.17 11.7 0.2 3.7 3 1 0 3 3 3 2 CCCH zinc finger in TRM13 protein WRC PF08879.10 KFR06498.1 - 0.02 14.6 1.0 0.25 11.0 0.2 2.6 2 0 0 2 2 2 0 WRC CxC6 PF18721.1 KFR06498.1 - 2.1 8.7 6.7 7.9 6.8 2.7 2.4 1 1 1 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases Cyclin_N PF00134.23 KFR06499.1 - 8.9e-16 57.8 1.6 1.2e-12 47.7 0.3 2.6 2 0 0 2 2 2 2 Cyclin, N-terminal domain UPF0253 PF06786.12 KFR06499.1 - 0.13 12.6 0.3 0.39 11.0 0.3 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0253) DUF3510 PF12022.8 KFR06499.1 - 0.22 11.9 2.0 0.9 9.9 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) DEAD PF00270.29 KFR06500.1 - 1.1e-53 181.6 0.0 1.9e-53 180.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFR06500.1 - 0.0083 16.1 0.8 0.025 14.6 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3698 PF12479.8 KFR06500.1 - 0.15 12.6 0.8 0.56 10.8 0.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3698) ASC PF00858.24 KFR06516.1 - 5e-23 81.8 0.0 6.1e-23 81.5 0.0 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DnaJ_C PF01556.18 KFR06519.1 - 1.8e-24 86.5 0.3 2.4e-24 86.1 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFR06519.1 - 2.8e-06 27.4 0.2 4.7e-06 26.6 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain UNC119_bdg PF15435.6 KFR06520.1 - 1.8e-106 354.1 0.9 2e-106 353.9 0.9 1.0 1 0 0 1 1 1 1 UNC119-binding protein C5orf30 homologue Carboxyl_trans PF01039.22 KFR06533.1 - 2.6e-153 511.3 0.1 3e-153 511.0 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 KFR06533.1 - 0.00022 20.8 0.2 0.21 11.1 0.0 2.3 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) Sema PF01403.19 KFR06540.1 - 2.8e-134 448.1 0.1 4.4e-134 447.5 0.1 1.2 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 KFR06540.1 - 4.5e-07 30.3 4.0 1.3e-06 28.9 4.0 1.8 1 0 0 1 1 1 1 Plexin repeat DUF3481 PF11980.8 KFR06540.1 - 0.055 13.2 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein COMM_domain PF07258.14 KFR06541.1 - 6.5e-06 26.2 3.0 1.9e-05 24.7 0.0 2.4 2 1 0 2 2 2 1 COMM domain SKA2 PF16740.5 KFR06541.1 - 0.013 15.3 2.5 0.056 13.2 1.6 1.8 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 ARF7EP_C PF14949.6 KFR06542.1 - 2.4e-36 124.5 11.2 2.7e-36 124.4 11.2 1.0 1 0 0 1 1 1 1 ARF7 effector protein C-terminus Peptidase_M1 PF01433.20 KFR06543.1 - 2.3e-59 200.6 0.1 6.5e-59 199.1 0.1 1.7 1 1 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KFR06543.1 - 1.5e-51 175.8 2.0 2.3e-51 175.2 2.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KFR06543.1 - 2.1e-23 83.5 0.3 5e-23 82.3 0.1 1.8 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Clat_adaptor_s PF01217.20 KFR06544.1 - 1.4e-41 141.7 2.9 1.7e-41 141.5 2.9 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CDO_I PF05995.12 KFR06545.1 - 1.1e-48 164.7 0.0 1.5e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KFR06545.1 - 0.00088 18.8 0.3 0.0043 16.5 0.3 1.8 1 1 0 1 1 1 1 PCO_ADO EMP24_GP25L PF01105.24 KFR06546.1 - 2.8e-34 118.7 0.0 3.1e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Occludin_ELL PF07303.13 KFR06547.1 - 1.6e-30 105.8 10.3 2.5e-30 105.2 10.3 1.3 1 0 0 1 1 1 1 Occludin homology domain MARVEL PF01284.23 KFR06547.1 - 4.7e-17 62.3 10.5 6.1e-17 62.0 10.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain Sec34 PF04136.15 KFR06547.1 - 0.0029 17.5 1.6 0.0034 17.3 0.2 1.7 2 0 0 2 2 2 1 Sec34-like family Tex_N PF09371.10 KFR06547.1 - 0.021 14.5 2.0 0.035 13.8 2.0 1.3 1 0 0 1 1 1 0 Tex-like protein N-terminal domain DUF1241 PF06840.11 KFR06547.1 - 0.068 12.8 0.4 0.13 11.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Ssl1 PF04056.14 KFR06548.1 - 1.1e-88 296.1 0.1 1.5e-88 295.6 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 KFR06548.1 - 4.2e-13 49.9 0.0 9.7e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.12 KFR06548.1 - 3.5e-10 40.0 25.5 3.4e-09 36.8 18.7 2.9 2 1 0 2 2 2 2 TFIIH C1-like domain VWA PF00092.28 KFR06548.1 - 0.00016 22.0 0.0 0.00023 21.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain HscB_4_cys PF18256.1 KFR06548.1 - 0.04 13.7 0.1 0.04 13.7 0.1 2.5 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif IBR PF01485.21 KFR06548.1 - 0.091 13.0 17.0 0.049 13.9 9.3 2.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_4 PF14570.6 KFR06548.1 - 5.4 6.9 23.5 5.5 6.9 14.8 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain NLRC4_HD PF17889.1 KFR06549.1 - 6e-34 116.6 0.6 2.8e-33 114.5 0.6 2.3 1 0 0 1 1 1 1 NLRC4 helical domain NACHT PF05729.12 KFR06549.1 - 2.6e-26 92.5 0.2 9.1e-26 90.7 0.0 2.1 2 0 0 2 2 2 1 NACHT domain BIR PF00653.21 KFR06549.1 - 5.1e-17 62.3 3.8 7.5e-17 61.7 0.2 2.6 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain NOD2_WH PF17779.1 KFR06549.1 - 8.8e-07 29.2 0.6 6.7e-06 26.3 0.1 2.8 2 1 1 3 3 3 1 NOD2 winged helix domain AAA_30 PF13604.6 KFR06549.1 - 0.005 16.6 0.0 0.0092 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KFR06549.1 - 0.011 15.8 0.0 0.035 14.1 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KFR06549.1 - 0.082 13.2 0.0 2.1 8.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KFR06549.1 - 0.1 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain T6PP_N PF18572.1 KFR06549.1 - 0.14 12.0 0.7 7.7 6.4 0.1 3.1 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain LRR_1 PF00560.33 KFR06549.1 - 0.88 10.4 6.5 83 4.4 0.2 5.8 4 0 0 4 4 4 0 Leucine Rich Repeat SMN PF06003.12 KFR06550.1 - 1.5e-125 417.8 5.9 1.6e-125 417.6 5.9 1.0 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 KFR06550.1 - 0.0012 18.8 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 Tudor domain ASXH PF13919.6 KFR06550.1 - 0.099 12.7 1.4 1.9 8.5 0.4 2.1 2 0 0 2 2 2 0 Asx homology domain 4F5 PF04419.14 KFR06551.1 - 2.5e-08 34.7 8.5 2.5e-08 34.7 8.5 2.1 2 0 0 2 2 2 1 4F5 protein family Myb_DNA-bind_7 PF15963.5 KFR06552.1 - 5e-29 100.0 2.6 5e-29 100.0 2.6 2.7 3 1 0 4 4 4 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KFR06552.1 - 0.00054 20.1 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Afi1 PF07792.12 KFR06552.1 - 8.8 6.8 14.1 11 6.6 1.1 2.6 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking HS1_rep PF02218.15 KFR06559.1 - 4.4e-63 209.3 38.3 2.6e-17 62.8 1.2 5.3 5 0 0 5 5 5 4 Repeat in HS1/Cortactin SH3_9 PF14604.6 KFR06559.1 - 3.5e-17 62.0 0.2 7.1e-17 61.0 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFR06559.1 - 7.9e-16 57.4 0.2 1.6e-15 56.4 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFR06559.1 - 3.6e-08 33.0 0.0 9.3e-08 31.6 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain TMEM210 PF15195.6 KFR06559.1 - 0.025 15.0 0.2 60 4.1 0.0 4.0 2 2 2 4 4 4 0 TMEM210 family 7tm_4 PF13853.6 KFR06560.1 - 2.7e-52 178.2 12.5 3.1e-52 178.0 12.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFR06560.1 - 1.2e-25 90.3 15.3 1.7e-25 89.8 15.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFR06560.1 - 0.0013 18.4 4.0 0.0013 18.4 4.0 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFR06560.1 - 0.0044 16.4 8.7 0.0079 15.6 8.7 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv NDK PF00334.19 KFR06561.1 - 3.4e-18 66.0 0.0 4.4e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Ras PF00071.22 KFR06562.1 - 1.2e-26 93.3 0.2 1.5e-26 93.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR06562.1 - 5.7e-20 71.7 0.1 1e-19 70.9 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR06562.1 - 3.6e-06 26.6 0.0 5.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFR06562.1 - 7e-05 22.4 0.0 0.00025 20.7 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFR06562.1 - 0.0014 18.0 0.1 0.0028 17.0 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1_Xtn PF16897.5 KFR06562.1 - 0.0084 16.1 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain ATP_bind_1 PF03029.17 KFR06562.1 - 0.032 14.0 0.1 0.041 13.7 0.1 1.3 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein NOG1 PF06858.14 KFR06562.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.6 1 1 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) TGF_beta PF00019.20 KFR06641.1 - 3.4e-33 114.7 0.7 6.8e-33 113.8 0.7 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFR06641.1 - 1.7e-18 67.3 0.0 2.9e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 TGF-beta propeptide Ubiq_cyt_C_chap PF03981.12 KFR06642.1 - 9.2e-42 142.5 0.1 1.3e-41 142.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Chlorophyllase PF07224.11 KFR06642.1 - 0.098 11.6 0.4 0.15 11.1 0.4 1.2 1 0 0 1 1 1 0 Chlorophyllase FAM83 PF07894.12 KFR06643.1 - 3.8e-103 344.8 0.2 1.3e-102 343.1 0.0 1.8 2 0 0 2 2 2 1 FAM83 A-H PLDc_2 PF13091.6 KFR06643.1 - 0.00039 20.3 0.0 0.00077 19.4 0.0 1.5 1 0 0 1 1 1 1 PLD-like domain SPACA9 PF15120.6 KFR06643.1 - 0.11 12.3 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 Peptidase_M10 PF00413.24 KFR06644.1 - 1.4e-62 210.3 0.2 2.7e-62 209.3 0.2 1.5 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 KFR06644.1 - 2e-54 181.3 20.2 9.1e-16 57.5 0.9 4.5 4 0 0 4 4 4 4 Hemopexin DUF3377 PF11857.8 KFR06644.1 - 2.6e-29 101.0 1.8 4.1e-29 100.3 1.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) PG_binding_1 PF01471.18 KFR06644.1 - 3.3e-11 43.2 0.2 6.8e-11 42.2 0.2 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.24 KFR06644.1 - 0.0002 21.0 1.4 0.43 10.2 0.1 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) DUF4293 PF14126.6 KFR06644.1 - 0.0027 17.9 0.1 0.0048 17.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4293) Peptidase_M66 PF10462.9 KFR06644.1 - 0.04 12.9 0.4 0.066 12.2 0.4 1.3 1 0 0 1 1 1 0 Peptidase M66 Metallopep PF12044.8 KFR06644.1 - 0.048 12.3 0.1 0.071 11.7 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_3 PF13582.6 KFR06644.1 - 0.058 13.9 0.2 0.18 12.3 0.3 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 KFR06644.1 - 0.077 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M54 DUF4953 PF16313.5 KFR06644.1 - 0.095 11.9 0.2 0.17 11.1 0.2 1.3 1 0 0 1 1 1 0 Met-zincin Reprolysin_4 PF13583.6 KFR06644.1 - 0.25 10.9 0.1 0.49 10.0 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Atg8 PF02991.16 KFR06645.1 - 2.9e-45 152.7 0.4 3.2e-45 152.6 0.4 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KFR06645.1 - 2.5e-06 27.8 0.0 3.1e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Cytochrom_B559a PF00284.20 KFR06645.1 - 0.13 12.1 0.1 0.38 10.5 0.1 1.8 1 1 1 2 2 2 0 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit Robl_LC7 PF03259.17 KFR06646.1 - 3.6e-26 90.8 0.0 3.9e-26 90.6 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 KFR06646.1 - 3.7e-05 23.6 0.0 4.3e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 UPF0176_N PF17773.1 KFR06646.1 - 0.061 13.7 0.0 0.069 13.5 0.0 1.2 1 0 0 1 1 1 0 UPF0176 acylphosphatase like domain HECT PF00632.25 KFR06647.1 - 2.2e-98 329.5 0.2 2.9e-98 329.1 0.2 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KFR06647.1 - 2.7e-45 152.1 19.5 7e-14 51.6 0.9 4.6 4 0 0 4 4 4 4 WW domain C2 PF00168.30 KFR06647.1 - 9.9e-14 51.5 0.5 2.5e-13 50.2 0.5 1.7 1 0 0 1 1 1 1 C2 domain AdoHcyase PF05221.17 KFR06648.1 - 6.8e-136 452.3 0.0 1.8e-72 244.0 0.2 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KFR06648.1 - 8.9e-86 286.0 3.1 1.4e-85 285.3 3.1 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KFR06648.1 - 1.7e-09 37.3 0.1 3e-09 36.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KFR06648.1 - 5.6e-06 26.0 0.2 9.5e-06 25.3 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KFR06648.1 - 0.0014 18.8 0.1 0.0031 17.7 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.18 KFR06648.1 - 0.0035 17.2 1.1 0.013 15.4 1.1 2.0 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Oxidored_nitro PF00148.19 KFR06648.1 - 0.022 13.5 0.1 1.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase ELFV_dehydrog PF00208.21 KFR06648.1 - 0.026 14.3 0.2 0.053 13.2 0.2 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.6 KFR06648.1 - 0.085 13.3 0.2 0.23 11.9 0.2 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding eIF-5_eIF-2B PF01873.17 KFR06650.1 - 1.4e-41 141.0 0.2 2.5e-41 140.2 0.2 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Cytochrom_c3_2 PF14537.6 KFR06650.1 - 1.8 9.1 6.8 0.13 12.7 1.0 2.1 2 1 0 2 2 2 0 Cytochrome c3 RRM_1 PF00076.22 KFR06651.1 - 1.5e-12 47.1 0.0 2.7e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFR06651.1 - 0.0097 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SKA2 PF16740.5 KFR06651.1 - 0.04 13.7 3.7 1.5 8.6 0.2 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF4349 PF14257.6 KFR06651.1 - 0.055 12.9 1.1 0.084 12.3 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Perilipin PF03036.16 KFR06653.1 - 1.8e-50 172.1 1.9 2e-50 172.0 1.9 1.0 1 0 0 1 1 1 1 Perilipin family EspB PF05802.11 KFR06653.1 - 0.023 14.7 0.3 0.025 14.6 0.3 1.0 1 0 0 1 1 1 0 Enterobacterial EspB protein Snf7 PF03357.21 KFR06654.1 - 3.2e-46 157.1 9.0 3.6e-46 156.9 9.0 1.0 1 0 0 1 1 1 1 Snf7 SYF2 PF08231.12 KFR06654.1 - 0.00033 21.1 1.2 0.00041 20.8 1.2 1.2 1 0 0 1 1 1 1 SYF2 splicing factor ABC_tran_CTD PF16326.5 KFR06654.1 - 1.1 9.5 13.2 6.7 7.0 0.5 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain zf-C2H2 PF00096.26 KFR06655.1 - 9.6e-37 123.4 111.7 3.3e-05 24.1 1.3 12.4 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFR06655.1 - 9.6e-33 111.2 97.2 7e-09 35.7 0.0 13.3 13 0 0 13 13 13 10 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR06655.1 - 1.3e-30 103.4 99.7 0.00083 20.0 0.4 12.4 12 0 0 12 12 12 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFR06655.1 - 1.6e-14 53.7 79.4 0.0085 16.4 2.6 11.7 10 1 1 11 11 11 9 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFR06655.1 - 6.9e-06 25.9 88.3 4.7e-05 23.3 2.4 12.1 12 0 0 12 12 12 6 C2H2-type zinc finger zf-met PF12874.7 KFR06655.1 - 3.5e-05 24.0 70.1 0.88 10.0 0.3 11.3 11 0 0 11 11 11 7 Zinc-finger of C2H2 type BolA PF01722.18 KFR06655.1 - 4.7e-05 23.6 14.5 0.0082 16.4 0.1 5.3 4 2 1 5 5 5 2 BolA-like protein zf-C2H2_2 PF12756.7 KFR06655.1 - 0.00033 20.9 65.0 0.2 12.0 0.5 8.4 2 2 7 9 9 9 6 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 KFR06655.1 - 0.0015 18.3 10.3 1.5 8.6 0.8 4.0 3 0 0 3 3 3 3 GAGA factor zf-C2HE PF16278.5 KFR06655.1 - 0.011 16.1 5.2 0.028 14.9 1.5 9.9 6 5 4 10 10 10 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 KFR06655.1 - 0.018 14.8 0.1 0.018 14.8 0.1 10.9 11 2 0 11 11 11 0 C2H2-type zinc-finger domain zf-CHCC PF10276.9 KFR06655.1 - 0.41 10.7 8.6 18 5.5 0.1 4.9 4 0 0 4 4 4 0 Zinc-finger domain Tim17 PF02466.19 KFR06656.1 - 8.3e-14 51.9 0.6 1.8e-13 50.8 0.8 1.4 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family EF-hand_5 PF13202.6 KFR06657.1 - 2.8e-07 29.7 4.2 1.4e-05 24.3 0.9 2.7 1 1 1 2 2 2 2 EF hand EF-hand_1 PF00036.32 KFR06657.1 - 2e-06 27.0 2.8 1e-05 24.7 0.7 2.5 1 1 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KFR06657.1 - 5e-06 26.3 1.7 0.0002 21.2 0.4 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KFR06657.1 - 2.7e-05 23.7 1.5 0.0019 18.0 0.4 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KFR06657.1 - 0.00072 20.0 2.1 0.0031 17.9 0.3 2.3 2 1 0 2 2 2 1 EF-hand domain pair Spore_III_AB PF09548.10 KFR06657.1 - 0.0064 16.6 0.6 0.011 15.9 0.6 1.3 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) ABM PF03992.16 KFR06657.1 - 0.0098 16.0 0.0 0.024 14.7 0.0 1.7 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase PH_17 PF18012.1 KFR06659.1 - 6.3e-26 89.9 0.1 1.2e-25 89.0 0.1 1.5 1 0 0 1 1 1 1 PH domain PDZ PF00595.24 KFR06659.1 - 1.3e-14 54.3 0.1 3.2e-14 53.0 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 KFR06659.1 - 9.9e-06 26.0 0.0 0.084 13.4 0.0 2.4 2 0 0 2 2 2 2 PH domain PDZ_6 PF17820.1 KFR06659.1 - 1.6e-05 24.6 0.0 3.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFR06659.1 - 0.0018 18.6 0.1 0.0044 17.3 0.1 1.6 1 0 0 1 1 1 1 PDZ domain DUF3509 PF12021.8 KFR06659.1 - 0.088 12.6 0.0 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3509) HMG_box PF00505.19 KFR06660.1 - 6.3e-11 42.5 0.0 1.3e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFR06660.1 - 2.2e-09 37.8 0.0 4.3e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.13 KFR06660.1 - 0.016 15.8 0.3 0.025 15.2 0.3 1.5 1 0 0 1 1 1 0 YABBY protein IMUP PF15761.5 KFR06660.1 - 0.016 15.9 8.2 0.016 15.9 8.2 1.7 2 0 0 2 2 2 0 Immortalisation up-regulated protein Mitofilin PF09731.9 KFR06660.1 - 0.32 9.8 4.1 0.4 9.5 4.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Glyco_hydro_47 PF01532.20 KFR06663.1 - 9.9e-102 341.2 0.0 1.8e-101 340.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 DUF3689 PF12463.8 KFR06664.1 - 9.1e-142 471.9 15.6 1.5e-141 471.2 15.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3689) Myosin_head PF00063.21 KFR06665.1 - 1.7e-291 968.4 1.2 1.7e-291 968.4 1.2 3.3 4 0 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KFR06665.1 - 1.5e-169 566.1 266.8 2.1e-169 565.6 266.8 1.2 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 KFR06665.1 - 2.1e-13 49.9 6.8 4.8e-13 48.7 6.8 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Filament PF00038.21 KFR06665.1 - 5.7e-06 26.1 40.0 5.7e-06 26.1 40.0 9.2 1 1 7 8 8 8 3 Intermediate filament protein Sec2p PF06428.11 KFR06665.1 - 0.0015 18.5 7.6 0.0015 18.5 7.6 17.2 1 1 17 18 18 18 2 GDP/GTP exchange factor Sec2p FPP PF05911.11 KFR06665.1 - 0.0016 16.8 7.3 0.0016 16.8 7.3 8.5 1 1 7 9 9 9 2 Filament-like plant protein, long coiled-coil IQ PF00612.27 KFR06665.1 - 0.022 14.5 1.4 0.17 11.7 0.3 2.8 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_22 PF13401.6 KFR06665.1 - 0.096 13.0 0.0 0.096 13.0 0.0 7.2 4 2 2 6 6 6 0 AAA domain AAA_16 PF13191.6 KFR06665.1 - 0.56 10.6 0.0 0.56 10.6 0.0 7.1 2 1 1 4 4 4 0 AAA ATPase domain DUF1664 PF07889.12 KFR06665.1 - 1.4 9.0 143.7 1 9.4 1.7 13.5 1 1 7 13 13 13 0 Protein of unknown function (DUF1664) CAAX_1 PF15895.5 KFR06666.1 - 0.55 10.1 6.5 0.58 10.0 6.5 1.1 1 0 0 1 1 1 0 CAAX box cerebral protein 1 GSH_synth_ATP PF03917.17 KFR06668.1 - 2.9e-125 417.9 0.0 3.3e-125 417.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KFR06668.1 - 2e-33 114.9 0.2 4.3e-33 113.8 0.2 1.6 1 0 0 1 1 1 1 Eukaryotic glutathione synthase AMP-binding PF00501.28 KFR06669.1 - 2.3e-96 323.0 0.0 2.7e-96 322.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFR06669.1 - 4.3e-24 85.3 0.0 9.5e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KFR06669.1 - 0.0011 18.8 0.2 0.0033 17.3 0.2 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Y_phosphatase PF00102.27 KFR06671.1 - 4.8e-147 487.8 1.9 8e-81 271.1 0.1 2.6 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 KFR06671.1 - 3.9e-29 100.8 2.2 2.6e-11 43.7 0.0 5.6 4 1 1 5 5 5 4 Fibronectin type III domain MAM PF00629.23 KFR06671.1 - 2.5e-24 86.0 0.0 6.7e-24 84.6 0.0 1.8 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu DSPc PF00782.20 KFR06671.1 - 3.2e-09 36.7 0.1 0.0017 18.2 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFR06671.1 - 7.4e-05 22.8 0.0 0.024 14.6 0.0 2.3 2 0 0 2 2 2 2 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFR06671.1 - 0.00013 22.1 0.0 0.77 9.9 0.0 2.7 2 0 0 2 2 2 2 Inositol hexakisphosphate Amnionless PF14828.6 KFR06671.1 - 0.016 14.0 0.2 0.028 13.2 0.2 1.3 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 KFR06671.1 - 0.025 15.5 0.0 0.061 14.2 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PTP_tm PF18861.1 KFR06671.1 - 0.025 14.6 0.0 0.061 13.3 0.0 1.7 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J I-set PF07679.16 KFR06671.1 - 0.043 13.9 0.0 0.098 12.7 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_2 PF13895.6 KFR06671.1 - 0.072 13.4 1.7 0.17 12.2 0.1 2.6 2 0 0 2 2 2 0 Immunoglobulin domain ig PF00047.25 KFR06671.1 - 0.086 13.0 0.5 0.22 11.7 0.1 1.9 2 0 0 2 2 1 0 Immunoglobulin domain DEP PF00610.21 KFR06672.1 - 3.5e-42 142.3 0.2 2.9e-21 75.3 0.0 3.4 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGEF PF00621.20 KFR06672.1 - 2.1e-36 125.9 1.8 6.7e-36 124.2 0.1 2.9 3 0 0 3 3 3 1 RhoGEF domain PDZ_6 PF17820.1 KFR06672.1 - 3.4e-08 33.2 0.0 0.00091 19.0 0.0 3.0 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 KFR06672.1 - 9.2e-08 32.3 0.0 0.006 16.9 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PH PF00169.29 KFR06672.1 - 6.8e-05 23.3 0.3 0.00045 20.7 0.3 2.5 2 0 0 2 2 2 1 PH domain PDZ_2 PF13180.6 KFR06672.1 - 0.0003 21.0 0.0 0.3 11.4 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PH_10 PF15411.6 KFR06672.1 - 0.0029 17.9 1.1 0.016 15.5 0.3 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain UPF1_Zn_bind PF09416.10 KFR06672.1 - 0.011 15.7 0.0 0.039 13.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) IQ_SEC7_PH PF16453.5 KFR06672.1 - 0.027 14.5 0.1 0.078 13.0 0.1 1.7 1 0 0 1 1 1 0 PH domain DUF3740 PF12548.8 KFR06673.1 - 1.4e-54 184.6 0.8 1.4e-54 184.6 0.8 2.3 3 0 0 3 3 3 1 Sulfatase protein Sulfatase PF00884.23 KFR06673.1 - 3.2e-48 164.7 1.3 4.9e-48 164.1 1.3 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFR06673.1 - 0.025 14.2 0.2 8.6 5.8 0.2 2.5 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KFR06673.1 - 0.039 14.2 0.0 6.9 7.0 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) TPR_MLP1_2 PF07926.12 KFR06673.1 - 0.37 10.9 4.1 2.6 8.1 0.1 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF5082 PF16888.5 KFR06673.1 - 8 6.8 8.1 2 8.7 0.1 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF5082) TRAM_LAG1_CLN8 PF03798.16 KFR06674.1 - 3.3e-27 95.5 12.8 5.2e-27 94.9 12.8 1.3 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 KFR06674.1 - 3.1e-20 71.6 0.5 7.7e-20 70.3 0.5 1.7 1 0 0 1 1 1 1 TRAM1-like protein DUF3544 PF12064.8 KFR06675.1 - 2.7e-96 321.8 20.1 2.7e-96 321.8 20.1 3.2 3 0 0 3 3 3 1 Protein kinase C-binding protein 1 Bromodomain PF00439.25 KFR06675.1 - 1.9e-16 59.9 0.0 5.9e-16 58.3 0.0 1.9 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 KFR06675.1 - 8.8e-07 28.7 13.1 8.8e-07 28.7 13.1 3.6 3 0 0 3 3 3 1 PHD-finger PWWP PF00855.17 KFR06675.1 - 2.2e-06 28.0 0.4 2.2e-06 28.0 0.4 2.5 2 0 0 2 2 2 1 PWWP domain DUF1640 PF07798.11 KFR06675.1 - 0.0002 21.5 2.6 0.0002 21.5 2.6 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1640) zf-MYND PF01753.18 KFR06675.1 - 0.0017 18.4 17.1 0.0017 18.4 17.1 4.1 3 1 0 3 3 3 1 MYND finger Hydrolase PF00702.26 KFR06676.1 - 1.9e-07 31.6 0.0 2.6e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sugar_tr PF00083.24 KFR06677.1 - 6.4e-88 295.6 26.5 2.1e-63 214.8 11.6 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFR06677.1 - 1.1e-29 103.6 47.1 1.3e-22 80.3 15.3 3.1 2 1 0 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.13 KFR06677.1 - 0.00073 18.1 4.0 0.00073 18.1 4.0 2.7 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KFR06677.1 - 0.045 12.2 15.6 0.029 12.8 3.4 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector Kdo PF06293.14 KFR06678.1 - 1.2e-08 34.6 0.0 1.4e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KFR06678.1 - 6.2e-06 25.8 0.0 7.2e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KFR06678.1 - 8.6e-05 22.6 0.1 0.00024 21.1 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFR06678.1 - 0.0032 16.8 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase_Tyr PF07714.17 KFR06678.1 - 0.0035 16.7 0.0 0.0043 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KFR06678.1 - 0.012 15.2 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 KFR06678.1 - 0.035 13.6 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL TERF2_RBM PF16772.5 KFR06678.1 - 0.054 12.9 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Telomeric repeat-binding factor 2 Rap1-binding motif Choline_kinase PF01633.20 KFR06678.1 - 0.079 12.5 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH_6_hur PF04655.14 KFR06678.1 - 0.14 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Na_sulph_symp PF00939.19 KFR06679.1 - 8.5e-101 338.3 16.0 9.9e-101 338.1 16.0 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KFR06679.1 - 3.4e-34 118.4 28.3 4.9e-18 65.4 1.8 3.1 2 1 1 3 3 3 3 Citrate transporter DUF2207 PF09972.9 KFR06679.1 - 0.027 13.2 0.2 0.027 13.2 0.2 2.5 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) DC_STAMP PF07782.13 KFR06680.1 - 4.6e-38 131.0 0.2 4.6e-38 131.0 0.2 1.8 2 1 0 2 2 2 1 DC-STAMP-like protein DUF1981 PF09324.10 KFR06680.1 - 1.5 8.7 4.0 0.45 10.4 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) 7tm_1 PF00001.21 KFR06681.1 - 6e-46 156.9 21.2 7.2e-46 156.6 21.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR06681.1 - 1.1e-07 31.5 18.6 2.5e-07 30.3 18.6 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 KFR06681.1 - 0.00029 20.2 19.8 0.0065 15.8 19.8 2.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 KFR06681.1 - 0.00035 20.3 15.3 0.00035 20.3 15.3 2.3 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx MORN PF02493.20 KFR06682.1 - 4.7e-36 120.5 67.9 7.2e-07 28.7 3.2 8.7 9 0 0 9 9 9 8 MORN repeat DUF776 PF05604.11 KFR06683.1 - 7.6e-70 235.0 9.4 1.2e-69 234.3 9.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF776) DUF776 PF05604.11 KFR06684.1 - 4.5e-56 190.1 6.2 7e-56 189.5 6.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF776) SIP1 PF04938.12 KFR06684.1 - 0.018 14.8 0.1 0.028 14.2 0.1 1.3 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) GST_N_3 PF13417.6 KFR06685.1 - 3.9e-11 43.2 0.0 7.4e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFR06685.1 - 8.3e-09 35.6 0.0 1.9e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFR06685.1 - 7.8e-08 32.5 0.0 1.9e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFR06685.1 - 3.9e-05 23.6 0.0 0.00013 22.0 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFR06685.1 - 4e-05 23.8 0.0 9.2e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFR06685.1 - 0.0028 17.8 0.0 0.0085 16.3 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KFR06685.1 - 0.11 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Nsp1 PF11501.8 KFR06685.1 - 0.16 12.0 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Non structural protein Nsp1 Scs3p PF10261.9 KFR06686.1 - 1.1e-20 74.2 17.1 4.5e-13 49.3 5.3 2.5 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.21 KFR06686.1 - 4.3e-05 23.3 2.9 4.3e-05 23.3 2.9 2.4 1 1 1 2 2 2 1 PAP2 superfamily ARL6IP6 PF15062.6 KFR06686.1 - 0.077 13.1 0.9 0.077 13.1 0.9 2.8 2 1 1 3 3 3 0 Haemopoietic lineage transmembrane helix CAP PF00188.26 KFR06687.1 - 1.8e-26 93.5 3.2 2.3e-26 93.1 3.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Peptidase_M24_C PF16188.5 KFR06687.1 - 0.16 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of peptidase_M24 Hormone_recep PF00104.30 KFR06689.1 - 1.3e-39 136.0 0.0 1.8e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFR06689.1 - 2.1e-25 89.0 13.5 3.6e-25 88.2 13.5 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) CRAL_TRIO PF00650.20 KFR06690.1 - 4.8e-33 114.1 0.0 6.6e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFR06690.1 - 2.9e-07 30.6 0.5 7.5e-07 29.2 0.5 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFR06690.1 - 2.9e-05 24.2 0.0 4.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Serinc PF03348.15 KFR06691.1 - 1.3e-177 591.0 17.4 1.5e-177 590.9 17.4 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) MIG-14_Wnt-bd PF06664.12 KFR06691.1 - 0.39 9.9 25.8 0.45 9.7 0.6 3.2 2 1 0 3 3 3 0 Wnt-binding factor required for Wnt secretion PKI PF02827.16 KFR06692.1 - 2.5e-20 72.4 0.2 2.7e-20 72.4 0.2 1.0 1 0 0 1 1 1 1 cAMP-dependent protein kinase inhibitor TC1 PF15063.6 KFR06692.1 - 0.077 12.9 0.0 0.08 12.8 0.0 1.0 1 0 0 1 1 1 0 Thyroid cancer protein 1 A_deaminase PF00962.22 KFR06693.1 - 1.7e-95 320.1 0.0 2e-95 319.9 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase IGFBP PF00219.18 KFR06694.1 - 2.8e-10 40.7 20.6 2.8e-10 40.7 20.6 2.6 2 1 0 2 2 2 1 Insulin-like growth factor binding protein VWC PF00093.18 KFR06694.1 - 1e-05 25.7 2.9 1e-05 25.7 2.9 3.1 3 1 0 3 3 3 1 von Willebrand factor type C domain Secapin PF17521.2 KFR06694.1 - 0.01 15.6 6.8 0.02 14.7 6.8 1.4 1 0 0 1 1 1 0 Honey bee peptides 7tm_1 PF00001.21 KFR06695.1 - 2.8e-42 144.9 4.7 3.6e-42 144.5 4.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ion_trans_2 PF07885.16 KFR06696.1 - 6.6e-27 93.3 13.0 1.3e-17 63.5 8.2 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 KFR06696.1 - 0.012 14.9 10.5 0.023 13.9 10.7 1.5 1 1 0 1 1 1 0 Ion transport protein C2 PF00168.30 KFR06697.1 - 3.5e-15 56.1 0.0 6e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain 14-3-3 PF00244.20 KFR06698.1 - 1.2e-108 361.7 10.4 1.4e-108 361.6 10.4 1.0 1 0 0 1 1 1 1 14-3-3 protein Peptidase_C98 PF15499.6 KFR06698.1 - 0.02 14.4 0.3 0.035 13.6 0.3 1.5 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase FliM PF02154.15 KFR06698.1 - 0.051 13.5 0.2 0.087 12.7 0.2 1.3 1 0 0 1 1 1 0 Flagellar motor switch protein FliM SF3A2 PF16835.5 KFR06698.1 - 0.12 12.8 0.4 0.34 11.3 0.2 1.8 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) DUF4518 PF15008.6 KFR06698.1 - 0.14 11.4 5.4 3.2 6.8 5.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) Virulence_fact PF13769.6 KFR06698.1 - 1.8 8.8 7.7 0.91 9.8 0.7 2.9 2 1 1 3 3 3 0 Virulence factor YabA PF06156.13 KFR06698.1 - 3.2 8.5 6.6 1.2 9.9 2.6 2.2 3 0 0 3 3 3 0 Initiation control protein YabA RRM_1 PF00076.22 KFR06699.1 - 2.9e-86 283.3 0.9 1.5e-20 72.8 0.0 5.2 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KFR06699.1 - 1.8e-29 101.7 0.3 3.9e-29 100.6 0.3 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.6 KFR06699.1 - 6.9e-05 22.8 0.5 3.5 7.7 0.0 4.4 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KFR06699.1 - 0.00029 20.9 0.6 12 6.1 0.0 4.9 4 3 0 4 4 4 1 RNA recognition motif RRM_3 PF08777.11 KFR06699.1 - 0.00049 20.1 1.0 1.3 9.1 0.1 3.6 4 0 0 4 4 4 1 RNA binding motif SET_assoc PF11767.8 KFR06699.1 - 0.0012 18.5 0.5 8.7 6.1 0.0 4.1 4 0 0 4 4 4 1 Histone lysine methyltransferase SET associated RRM_occluded PF16842.5 KFR06699.1 - 0.0022 17.8 0.0 8.7 6.3 0.0 4.1 5 0 0 5 5 5 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KFR06699.1 - 0.014 15.5 0.8 44 4.2 0.0 4.0 5 0 0 5 5 5 0 Limkain b1 UPF0524 PF15823.5 KFR06699.1 - 0.061 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 UPF0524 of C3orf70 OB_RNB PF08206.11 KFR06699.1 - 0.094 12.4 5.3 16 5.3 0.2 3.4 3 0 0 3 3 3 0 Ribonuclease B OB domain TPR_1 PF00515.28 KFR06700.1 - 1.4e-20 72.2 6.2 4.2e-10 39.0 0.4 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFR06700.1 - 1.7e-18 65.2 4.8 8.5e-08 31.7 0.5 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFR06700.1 - 2.6e-12 45.9 8.0 4.5e-05 23.3 0.2 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFR06700.1 - 6.4e-11 41.8 2.4 7.8e-05 22.3 0.4 2.6 1 1 1 2 2 2 2 TPR repeat TPR_16 PF13432.6 KFR06700.1 - 2e-09 37.9 1.3 7.1e-06 26.6 0.0 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFR06700.1 - 1.4e-07 31.7 2.1 0.0037 18.0 0.1 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFR06700.1 - 2.7e-07 30.5 5.6 6.2e-05 23.1 0.1 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFR06700.1 - 1e-06 28.9 4.7 0.0056 16.9 2.9 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFR06700.1 - 7.1e-06 26.4 8.7 7.5e-05 23.2 4.4 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFR06700.1 - 2.5e-05 24.3 6.8 0.0063 16.6 0.4 3.3 3 1 1 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 KFR06700.1 - 8.3e-05 22.3 0.9 0.094 12.8 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFR06700.1 - 0.00018 21.6 3.2 0.0026 17.9 0.5 2.3 2 1 1 3 3 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFR06700.1 - 0.00078 19.6 8.2 0.0028 17.8 7.9 1.9 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KFR06700.1 - 0.0019 18.7 6.9 0.4 11.4 0.5 4.0 3 2 1 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.17 KFR06700.1 - 0.0045 17.4 1.2 0.011 16.1 1.2 1.8 1 1 0 1 1 1 1 Bacterial transcriptional activator domain SRP_TPR_like PF17004.5 KFR06700.1 - 0.052 13.6 2.3 0.091 12.8 2.3 1.4 1 0 0 1 1 1 0 Putative TPR-like repeat MIT PF04212.18 KFR06700.1 - 0.15 12.1 9.4 5.1 7.2 0.7 4.1 2 2 3 5 5 5 0 MIT (microtubule interacting and transport) domain DUF627 PF04781.12 KFR06700.1 - 0.39 10.8 7.4 7.1 6.7 5.7 2.5 2 1 0 2 2 1 0 Protein of unknown function (DUF627) SHNi-TPR PF10516.9 KFR06700.1 - 0.9 9.0 6.8 4.1 6.9 0.1 3.6 4 0 0 4 4 4 0 SHNi-TPR TPR_10 PF13374.6 KFR06700.1 - 1.6 8.7 6.3 0.59 10.1 0.7 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 KFR06701.1 - 4e-52 177.2 0.6 4e-51 173.9 0.6 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR06701.1 - 3.6e-35 121.5 0.8 1.9e-32 112.6 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Mst1_SARAH PF11629.8 KFR06701.1 - 3.9e-27 94.1 2.6 8.8e-27 92.9 2.6 1.7 1 0 0 1 1 1 1 C terminal SARAH domain of Mst1 DUF1192 PF06698.11 KFR06701.1 - 0.0038 17.2 0.0 0.01 15.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) Haspin_kinase PF12330.8 KFR06701.1 - 0.0048 15.9 0.3 2.3 7.1 0.1 2.3 1 1 1 2 2 2 2 Haspin like kinase domain Abi_2 PF07751.11 KFR06701.1 - 0.0062 16.8 1.2 0.11 12.8 0.0 2.3 2 0 0 2 2 2 1 Abi-like protein Pkinase_fungal PF17667.1 KFR06701.1 - 0.019 13.7 0.0 0.039 12.7 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Phage_Mu_Gam PF07352.12 KFR06701.1 - 0.36 10.7 4.7 0.15 11.9 1.4 2.1 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Nore1-SARAH PF16517.5 KFR06701.1 - 1.9 8.5 5.8 0.42 10.6 0.8 2.7 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain DUF4611 PF15387.6 KFR06701.1 - 3.2 8.0 12.0 0.046 13.9 1.8 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4611) Ion_trans PF00520.31 KFR06702.1 - 2.9e-45 154.4 0.6 3.8e-45 154.0 0.6 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFR06702.1 - 3.8e-30 104.1 0.1 8.2e-30 103.0 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFR06702.1 - 2e-10 40.5 4.6 2e-10 40.5 4.6 2.3 3 0 0 3 3 3 1 Ion channel BTB_3 PF16017.5 KFR06702.1 - 0.047 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain VWA PF00092.28 KFR06703.1 - 1.4e-101 338.0 0.2 1e-52 178.9 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 KFR06703.1 - 1.5e-38 131.7 0.3 5.3e-18 65.6 0.1 2.6 3 0 0 3 3 3 2 von Willebrand factor type A domain FXa_inhibition PF14670.6 KFR06703.1 - 7.9e-30 102.8 61.3 1.2e-08 35.1 9.4 4.5 4 0 0 4 4 4 4 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFR06703.1 - 2.8e-19 68.7 30.5 3e-07 30.2 2.7 5.0 4 0 0 4 4 4 4 Complement Clr-like EGF-like EGF_CA PF07645.15 KFR06703.1 - 1.3e-18 66.9 52.2 2e-06 27.9 6.0 4.4 4 0 0 4 4 4 4 Calcium-binding EGF domain EGF PF00008.27 KFR06703.1 - 3e-12 46.6 49.2 0.00083 19.6 5.2 4.6 4 0 0 4 4 4 4 EGF-like domain Matrilin_ccoil PF10393.9 KFR06703.1 - 3.2e-12 46.1 1.1 8.7e-12 44.7 1.1 1.8 1 0 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin hEGF PF12661.7 KFR06703.1 - 7.1e-06 26.5 37.8 0.13 12.9 1.5 5.1 4 0 0 4 4 4 3 Human growth factor-like EGF EGF_3 PF12947.7 KFR06703.1 - 0.012 15.7 49.6 0.066 13.4 3.7 4.7 4 0 0 4 4 4 0 EGF domain ClpB_D2-small PF10431.9 KFR06703.1 - 0.072 13.2 0.0 4.5 7.4 0.0 2.5 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein EGF_MSP1_1 PF12946.7 KFR06703.1 - 9.7 6.3 29.9 0.41 10.7 3.0 4.7 4 1 0 4 4 4 0 MSP1 EGF domain 1 BTD PF09270.10 KFR06704.1 - 9.3e-67 224.0 0.0 1.6e-66 223.2 0.0 1.4 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.11 KFR06704.1 - 3.5e-44 151.1 0.7 1.5e-43 149.1 0.7 2.0 1 1 0 1 1 1 1 LAG1, DNA binding TIG PF01833.24 KFR06704.1 - 0.0019 18.2 0.0 0.0059 16.7 0.0 1.9 2 0 0 2 2 2 1 IPT/TIG domain Ig_2 PF13895.6 KFR06705.1 - 5.9e-08 32.9 0.0 0.00075 19.8 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 KFR06705.1 - 1.9e-07 31.6 0.0 0.0027 18.3 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFR06705.1 - 1.4e-06 28.3 0.1 0.049 13.8 0.2 2.6 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFR06705.1 - 0.00013 21.9 0.0 0.069 13.2 0.0 3.0 3 0 0 3 3 3 1 Immunoglobulin I-set domain V-set PF07686.17 KFR06705.1 - 0.0002 21.5 1.1 0.12 12.6 0.6 2.7 2 2 0 2 2 2 2 Immunoglobulin V-set domain Ig_C19orf38 PF17737.1 KFR06705.1 - 0.00077 19.7 0.0 0.12 12.7 0.0 2.2 2 0 0 2 2 2 1 Ig domain in C19orf38 (HIDE1) ICAM_N PF03921.14 KFR06705.1 - 0.042 13.5 0.0 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 Intercellular adhesion molecule (ICAM), N-terminal domain RRM_1 PF00076.22 KFR06706.1 - 6e-14 51.6 0.0 9e-14 51.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFR06706.1 - 0.0001 22.3 0.0 0.00026 21.0 0.0 1.7 1 0 0 1 1 1 1 RNA binding motif 4_1_CTD PF05902.13 KFR06707.1 - 1.4e-33 115.2 3.2 1.4e-33 115.2 3.2 2.5 2 0 0 2 2 2 1 4.1 protein C-terminal domain (CTD) FERM_C PF09380.10 KFR06707.1 - 5.4e-25 87.6 0.0 1.1e-24 86.6 0.0 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KFR06707.1 - 4.2e-22 77.9 0.3 1.8e-21 75.8 0.2 2.1 2 0 0 2 2 2 1 FERM N-terminal domain SAB PF04382.13 KFR06707.1 - 5.6e-21 74.4 2.3 1.8e-20 72.8 2.3 2.0 1 0 0 1 1 1 1 SAB domain FERM_M PF00373.18 KFR06707.1 - 2.3e-20 73.1 0.0 6.1e-20 71.8 0.0 1.7 1 0 0 1 1 1 1 FERM central domain FA PF08736.11 KFR06707.1 - 2.5e-18 65.9 2.6 6.4e-18 64.6 2.6 1.8 1 0 0 1 1 1 1 FERM adjacent (FA) AAR2 PF05282.11 KFR06708.1 - 1.1e-72 245.4 0.0 1.2e-72 245.3 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein GKAP PF03359.13 KFR06709.1 - 1.9e-147 491.3 11.1 1.9e-147 491.3 11.1 3.1 3 0 0 3 3 3 1 Guanylate-kinase-associated protein (GKAP) protein Homeobox_KN PF05920.11 KFR06710.1 - 0.00076 19.3 3.1 0.0014 18.5 3.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain EF-hand_1 PF00036.32 KFR06711.1 - 4.9e-16 57.0 9.1 1.3e-07 30.7 1.6 4.4 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 KFR06711.1 - 1.1e-13 51.4 6.1 6.6e-07 29.7 0.2 2.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KFR06711.1 - 2.5e-12 45.7 9.1 7.6e-08 31.7 0.9 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 KFR06711.1 - 2.4e-07 30.5 7.4 0.0083 15.9 0.1 3.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KFR06711.1 - 3.3e-06 26.3 2.9 1.8e-05 24.0 1.5 2.6 2 0 0 2 2 2 1 EF hand EF-hand_11 PF08976.11 KFR06711.1 - 0.00012 22.8 0.1 0.00084 20.2 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain GPHH PF16905.5 KFR06711.1 - 0.0016 18.2 0.0 0.23 11.2 0.0 2.3 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_9 PF14658.6 KFR06711.1 - 0.0018 18.6 0.0 2.1 8.8 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.13 KFR06711.1 - 0.0023 17.9 0.0 3.6 7.7 0.0 2.9 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) Syntaxin PF00804.25 KFR06711.1 - 0.0078 15.9 0.5 0.47 10.1 0.1 2.1 2 0 0 2 2 2 1 Syntaxin SPARC_Ca_bdg PF10591.9 KFR06711.1 - 0.025 14.9 0.7 0.06 13.7 0.2 1.7 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2267 PF10025.9 KFR06711.1 - 0.066 13.5 0.0 21 5.4 0.0 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2267) SurA_N_2 PF13623.6 KFR06711.1 - 0.069 13.0 0.1 2.8 7.8 0.0 2.1 2 0 0 2 2 2 0 SurA N-terminal domain Rab5ip PF07019.12 KFR06712.1 - 2.6e-18 66.4 10.3 2.9e-18 66.2 10.3 1.0 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF2244 PF10003.9 KFR06712.1 - 0.022 14.4 0.8 0.022 14.4 0.8 1.9 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Clc-like PF07062.12 KFR06712.1 - 0.11 12.0 3.5 0.13 11.7 3.5 1.0 1 0 0 1 1 1 0 Clc-like Yip1 PF04893.17 KFR06712.1 - 0.47 10.1 9.3 2.8 7.6 9.0 1.9 1 1 0 1 1 1 0 Yip1 domain G_glu_transpept PF01019.21 KFR06713.1 - 2e-132 442.6 0.0 2.4e-132 442.3 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Nucleic_acid_bd PF13820.6 KFR06714.1 - 6e-55 185.1 0.2 1.8e-54 183.5 0.2 1.9 1 0 0 1 1 1 1 Putative nucleic acid-binding region DOR PF14839.6 KFR06715.1 - 3.5e-43 148.4 7.8 6.2e-42 144.3 3.9 2.2 2 1 0 2 2 2 2 DOR family PIG-U PF06728.13 KFR06716.1 - 1.7e-105 353.2 49.5 1.9e-105 353.0 49.5 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U TLD PF07534.16 KFR06717.1 - 8e-19 68.2 0.0 5.5e-18 65.5 0.0 1.9 1 1 0 1 1 1 1 TLD RB_A PF01858.17 KFR06718.1 - 8.6e-80 267.2 2.0 4.7e-79 264.8 0.5 2.4 2 0 0 2 2 2 1 Retinoblastoma-associated protein A domain DUF3452 PF11934.8 KFR06718.1 - 3.5e-49 165.9 0.3 3.5e-49 165.9 0.3 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3452) RB_B PF01857.20 KFR06718.1 - 3.8e-49 166.1 0.2 1.7e-48 164.0 0.2 2.2 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain Rb_C PF08934.10 KFR06718.1 - 3.9e-07 30.0 0.7 1.1e-06 28.5 0.7 1.7 1 0 0 1 1 1 1 Rb C-terminal domain Endonuclease_5 PF04493.14 KFR06718.1 - 0.12 12.0 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Endonuclease V eIF-3c_N PF05470.12 KFR06718.1 - 2.1 6.5 4.7 3.3 5.9 2.3 2.3 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SNF2_N PF00176.23 KFR06719.1 - 6.2e-63 212.6 2.3 1e-62 211.9 2.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 KFR06719.1 - 3.7e-25 87.6 3.3 2.8e-13 49.5 0.7 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KFR06719.1 - 1.2e-16 61.0 0.0 3.7e-16 59.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFR06719.1 - 1.5e-07 31.6 0.1 7e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CHDCT2 PF08074.11 KFR06719.1 - 1.7e-05 25.1 0.8 0.37 11.0 0.0 3.7 3 0 0 3 3 3 2 CHDCT2 (NUC038) domain DEAD PF00270.29 KFR06719.1 - 0.00033 20.5 0.0 0.00061 19.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KFR06719.1 - 0.0062 15.7 0.1 0.037 13.2 0.1 2.2 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 BRK PF07533.16 KFR06719.1 - 0.04 13.5 1.1 0.23 11.1 0.2 2.5 2 0 0 2 2 2 0 BRK domain DUF3437 PF11919.8 KFR06719.1 - 0.12 12.3 0.0 0.4 10.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) Rap_GAP PF02145.15 KFR06720.1 - 0.12 11.9 0.0 3.1 7.3 0.0 2.6 2 0 0 2 2 2 0 Rap/ran-GAP Ndr PF03096.14 KFR06721.1 - 8.1e-125 415.2 0.0 9.5e-125 415.0 0.0 1.0 1 0 0 1 1 1 1 Ndr family Abhydrolase_1 PF00561.20 KFR06721.1 - 2.3e-05 24.2 0.0 0.00047 19.9 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold SH2 PF00017.24 KFR06722.1 - 9.9e-23 80.0 0.1 1.4e-22 79.5 0.1 1.2 1 0 0 1 1 1 1 SH2 domain SH3_2 PF07653.17 KFR06722.1 - 0.0041 16.8 0.0 0.0077 15.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFR06722.1 - 0.007 16.0 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFR06722.1 - 0.008 16.0 0.0 0.062 13.2 0.0 2.4 3 0 0 3 3 3 1 Variant SH3 domain SH3_16 PF18348.1 KFR06722.1 - 0.03 14.1 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain SH3_10 PF17902.1 KFR06722.1 - 0.098 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 SH3 domain DUF3776 PF12618.8 KFR06723.1 - 2e-26 92.4 22.5 2e-26 92.4 22.5 4.8 5 2 1 6 6 5 1 Protein of unknown function (DUF3776) Tudor_3 PF18115.1 KFR06723.1 - 3e-15 55.8 1.2 3.1e-13 49.3 0.5 3.1 3 0 0 3 3 3 1 DNA repair protein Crb2 Tudor domain PHD PF00628.29 KFR06723.1 - 2.6e-06 27.2 12.4 1.1e-05 25.2 12.4 2.2 1 0 0 1 1 1 1 PHD-finger Tudor_2 PF18104.1 KFR06723.1 - 1.7e-05 24.4 0.4 4.1e-05 23.2 0.4 1.7 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain DUF4537 PF15057.6 KFR06723.1 - 3.1e-05 24.0 0.2 0.00011 22.2 0.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4537) MBT PF02820.18 KFR06723.1 - 0.00027 21.2 0.6 0.0025 18.1 0.1 2.7 3 0 0 3 3 3 1 mbt repeat Tudor-knot PF11717.8 KFR06723.1 - 0.0021 17.9 2.2 0.011 15.6 1.4 2.7 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain LBR_tudor PF09465.10 KFR06723.1 - 0.013 15.3 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Rad9_Rad53_bind PF08605.10 KFR06723.1 - 0.023 14.9 3.1 0.57 10.4 0.1 3.1 4 0 0 4 4 4 0 Fungal Rad9-like Rad53-binding Agenet PF05641.12 KFR06723.1 - 0.033 14.6 2.7 1.5 9.3 0.2 3.3 2 0 0 2 2 2 0 Agenet domain zf-C2H2 PF00096.26 KFR06723.1 - 0.38 11.3 10.4 0.042 14.3 5.0 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type RhoGAP PF00620.27 KFR06724.1 - 1.3e-29 102.9 0.0 6.2e-29 100.8 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain MyTH4 PF00784.17 KFR06724.1 - 1.8e-25 89.5 0.3 1.7e-24 86.3 0.3 2.6 1 1 0 1 1 1 1 MyTH4 domain WW PF00397.26 KFR06724.1 - 3.2e-06 27.1 4.2 8.6e-06 25.7 4.2 1.8 1 0 0 1 1 1 1 WW domain RRM_1 PF00076.22 KFR06725.1 - 5.2e-42 141.5 0.0 4.6e-24 84.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KFR06725.1 - 6e-27 94.6 0.3 1.7e-26 93.1 0.3 1.8 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 KFR06725.1 - 6.3e-05 22.7 0.0 0.013 15.3 0.0 3.4 3 1 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KFR06725.1 - 0.0062 16.1 0.0 0.45 10.1 0.0 2.7 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 KFR06725.1 - 0.055 13.3 0.0 6.1 6.7 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1866) PRP38_assoc PF12871.7 KFR06725.1 - 0.91 10.2 57.7 0.18 12.4 50.2 2.5 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Romo1 PF10247.9 KFR06726.1 - 2.8e-26 91.7 22.0 3.3e-26 91.4 22.0 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 KFR06726.1 - 0.0082 16.5 9.8 0.0095 16.3 9.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Aminotran_5 PF00266.19 KFR06727.1 - 2.3e-91 306.5 0.0 2.7e-91 306.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFR06727.1 - 3.1e-09 36.5 0.1 4.7e-09 35.9 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KFR06727.1 - 0.00074 18.9 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 KFR06727.1 - 0.049 12.3 0.0 0.087 11.5 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 KFR06727.1 - 0.083 11.4 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme RRM_1 PF00076.22 KFR06728.1 - 1.9e-32 110.9 1.6 4.2e-09 36.1 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFR06728.1 - 0.027 14.5 0.1 2.5 8.2 0.0 3.4 5 0 0 5 5 5 0 RNA binding motif RRM_8 PF11835.8 KFR06728.1 - 0.09 13.0 0.0 0.53 10.5 0.0 2.1 2 0 0 2 2 2 0 RRM-like domain Copine PF07002.16 KFR06729.1 - 6e-82 274.3 0.0 2.3e-81 272.4 0.0 1.8 2 0 0 2 2 2 1 Copine C2 PF00168.30 KFR06729.1 - 5.4e-25 87.7 0.0 9.9e-13 48.3 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 KFR06729.1 - 4.6e-06 26.9 0.0 9.7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 KFR06729.1 - 0.0074 16.6 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain C2 PF00168.30 KFR06730.1 - 9.2e-41 138.3 0.2 2.5e-14 53.4 0.0 4.4 4 0 0 4 4 4 3 C2 domain FerB PF08150.12 KFR06730.1 - 3.7e-28 97.9 0.0 1.2e-27 96.3 0.0 2.0 1 0 0 1 1 1 1 FerB (NUC096) domain FerI PF08151.12 KFR06730.1 - 1.5e-17 63.4 0.0 3.1e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 FerI (NUC094) domain Ribosomal_L7Ae PF01248.26 KFR06730.1 - 0.68 9.7 2.5 7.6 6.3 0.1 3.0 3 0 0 3 3 3 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family C2 PF00168.30 KFR06731.1 - 7.3e-21 74.4 0.0 1.1e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 C2 domain Ferlin_C PF16165.5 KFR06732.1 - 2.4e-19 69.8 2.2 1.1e-09 38.4 0.7 2.2 1 1 1 2 2 2 2 Ferlin C-terminus ArfGap PF01412.18 KFR06733.1 - 1.4e-34 118.7 0.0 3.3e-34 117.5 0.0 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_2 PF12796.7 KFR06733.1 - 2.4e-20 72.9 3.3 6.2e-11 42.7 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) BAR_3 PF16746.5 KFR06733.1 - 1.9e-16 60.5 16.0 3.3e-16 59.7 16.0 1.2 1 0 0 1 1 1 1 BAR domain of APPL family SH3_1 PF00018.28 KFR06733.1 - 7.2e-13 47.9 2.5 1.1e-12 47.4 0.1 2.4 2 0 0 2 2 2 1 SH3 domain PH PF00169.29 KFR06733.1 - 5.1e-10 39.8 0.3 1.5e-09 38.3 0.3 1.9 1 0 0 1 1 1 1 PH domain Ank PF00023.30 KFR06733.1 - 1.1e-09 38.3 0.9 1.1e-06 28.9 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat SH3_9 PF14604.6 KFR06733.1 - 1.6e-09 37.5 0.1 4.7e-09 36.0 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFR06733.1 - 1.1e-08 34.6 0.1 3.7e-08 32.9 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain Ank_3 PF13606.6 KFR06733.1 - 3.8e-08 33.0 2.1 0.0004 20.6 0.1 3.7 4 0 0 4 4 3 2 Ankyrin repeat Ank_4 PF13637.6 KFR06733.1 - 2.6e-07 31.1 0.1 8.2e-07 29.5 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFR06733.1 - 5e-07 29.9 0.1 2.4e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF4404 PF14357.6 KFR06733.1 - 0.31 11.7 7.5 0.34 11.6 1.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) ExsD PF16806.5 KFR06733.1 - 0.65 9.9 5.3 0.3 11.0 1.3 2.2 2 0 0 2 2 2 0 Antiactivator protein ExsD CENP-Q PF13094.6 KFR06733.1 - 1.9 8.7 9.0 0.37 11.0 0.2 2.7 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Glyco_transf_29 PF00777.18 KFR06734.1 - 3.5e-72 243.1 0.0 4.1e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) TilS PF09179.11 KFR06734.1 - 0.015 15.7 0.3 0.036 14.6 0.3 1.5 1 0 0 1 1 1 0 TilS substrate binding domain G_glu_transpept PF01019.21 KFR06734.1 - 0.07 11.9 0.0 0.097 11.4 0.0 1.1 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase COPIIcoated_ERV PF07970.12 KFR06735.1 - 1.5e-94 316.0 1.1 1.8e-94 315.7 1.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KFR06735.1 - 2e-12 47.3 0.1 8e-12 45.3 0.0 2.0 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Furin-like_2 PF15913.5 KFR06747.1 - 3e-48 162.4 21.4 3e-48 162.4 21.4 1.5 2 0 0 2 2 2 1 Furin-like repeat, cysteine-rich PI31_Prot_N PF11566.8 KFR06748.1 - 1.5e-16 60.6 0.1 2.3e-16 60.0 0.0 1.3 1 1 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KFR06748.1 - 4.6e-07 30.9 16.0 1.1e-06 29.7 15.3 2.0 1 1 1 2 2 2 1 PI31 proteasome regulator DUF3516 PF12029.8 KFR06748.1 - 0.13 11.3 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) Rad21_Rec8_N PF04825.13 KFR06749.1 - 3.5e-38 130.1 0.5 1.2e-37 128.4 0.0 2.0 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Syntaphilin PF15290.6 KFR06750.1 - 5.8e-139 463.0 0.0 7.8e-139 462.6 0.0 1.1 1 0 0 1 1 1 1 Golgi-localised syntaxin-1-binding clamp CALCOCO1 PF07888.11 KFR06750.1 - 6.6e-05 22.0 6.6 8.8e-05 21.6 6.6 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Fez1 PF06818.15 KFR06750.1 - 0.0011 19.5 8.2 0.0017 18.8 8.2 1.3 1 0 0 1 1 1 1 Fez1 Exonuc_VII_L PF02601.15 KFR06750.1 - 0.009 15.6 3.2 0.012 15.2 3.2 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit Sec2p PF06428.11 KFR06750.1 - 0.013 15.4 1.4 0.013 15.4 1.4 2.4 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Sec8_exocyst PF04048.14 KFR06750.1 - 0.022 14.6 7.5 0.57 10.1 0.2 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain MPS2 PF17060.5 KFR06750.1 - 0.032 13.5 4.4 0.071 12.4 4.2 1.5 1 1 0 1 1 1 0 Monopolar spindle protein 2 Lebercilin PF15619.6 KFR06750.1 - 0.052 13.2 12.6 0.093 12.4 12.6 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease AAA_13 PF13166.6 KFR06750.1 - 0.079 11.6 5.4 0.1 11.2 5.4 1.0 1 0 0 1 1 1 0 AAA domain FAM76 PF16046.5 KFR06750.1 - 0.098 12.0 10.5 0.68 9.2 1.0 2.0 1 1 1 2 2 2 0 FAM76 protein ArAE_1_C PF11728.8 KFR06750.1 - 0.1 12.6 5.8 0.15 12.0 5.8 1.2 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain BST2 PF16716.5 KFR06750.1 - 0.11 13.1 10.7 0.094 13.3 9.0 1.7 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 DUF3584 PF12128.8 KFR06750.1 - 0.12 9.8 8.1 0.16 9.4 8.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PKcGMP_CC PF16808.5 KFR06750.1 - 0.13 12.1 15.7 0.039 13.8 6.0 3.1 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Spc7 PF08317.11 KFR06750.1 - 0.13 11.1 11.3 0.23 10.3 11.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein CcdA PF07362.12 KFR06750.1 - 0.16 12.4 1.4 0.34 11.4 1.4 1.5 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA TPR_MLP1_2 PF07926.12 KFR06750.1 - 0.17 12.0 12.1 6.1 6.9 5.7 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein ING PF12998.7 KFR06750.1 - 0.23 12.1 7.6 0.24 12.0 6.1 1.7 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding GlutR_dimer PF00745.20 KFR06750.1 - 0.27 11.7 3.9 0.19 12.2 1.7 1.8 1 1 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF16 PF01519.16 KFR06750.1 - 0.29 11.7 9.4 4.5 7.8 9.4 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 HMMR_N PF15905.5 KFR06750.1 - 0.3 10.5 13.1 0.46 9.9 13.1 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Laminin_II PF06009.12 KFR06750.1 - 0.3 11.1 4.0 0.53 10.3 4.0 1.4 1 0 0 1 1 1 0 Laminin Domain II UPF0242 PF06785.11 KFR06750.1 - 0.46 10.6 10.3 0.7 10.0 10.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 KFR06750.1 - 0.48 9.7 3.3 0.69 9.2 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF641 PF04859.12 KFR06750.1 - 0.59 10.5 8.4 0.072 13.4 0.9 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF745 PF05335.13 KFR06750.1 - 0.99 9.1 6.4 1.5 8.6 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) CC2-LZ PF16516.5 KFR06750.1 - 1 9.8 12.3 0.39 11.1 2.9 2.2 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator TMPIT PF07851.13 KFR06750.1 - 1.1 8.5 4.6 1.5 8.0 4.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4200 PF13863.6 KFR06750.1 - 1.3 9.4 12.8 1.8 9.0 3.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) FapA PF03961.13 KFR06750.1 - 1.4 7.4 5.8 1.9 7.0 5.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Golgin_A5 PF09787.9 KFR06750.1 - 1.7 8.1 12.5 4.1 6.8 12.5 1.6 1 1 0 1 1 1 0 Golgin subfamily A member 5 FlaC_arch PF05377.11 KFR06750.1 - 2.2 8.7 5.7 3.7 8.0 1.6 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) HR1 PF02185.16 KFR06750.1 - 3.2 7.9 11.4 1.4 9.1 1.7 2.6 1 1 2 3 3 3 0 Hr1 repeat Mto2_bdg PF12808.7 KFR06750.1 - 4.2 7.7 9.6 0.74 10.2 2.2 3.3 3 0 0 3 3 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Csm1_N PF18504.1 KFR06750.1 - 8.2 6.9 11.7 2.9 8.3 1.6 2.9 1 1 2 3 3 3 0 Csm1 N-terminal domain DUF948 PF06103.11 KFR06750.1 - 8.3 6.7 5.6 5.1 7.4 1.3 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) PDZ_6 PF17820.1 KFR06751.1 - 4.5e-24 84.1 0.1 2.5e-16 59.3 0.0 2.2 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 KFR06751.1 - 2.2e-19 69.6 2.2 2.8e-10 40.4 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFR06751.1 - 4.2e-10 39.8 0.1 4.5e-06 26.9 0.0 2.2 1 1 1 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 KFR06751.1 - 0.0004 20.3 0.2 0.93 9.5 0.0 2.3 2 0 0 2 2 2 2 Tricorn protease PDZ domain Aha1_N PF09229.11 KFR06751.1 - 0.011 16.0 0.1 0.017 15.4 0.1 1.2 1 0 0 1 1 1 0 Activator of Hsp90 ATPase, N-terminal FKBP_C PF00254.28 KFR06752.1 - 6.1e-29 100.2 0.0 6.7e-29 100.1 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase SEP PF08059.13 KFR06753.1 - 1.1e-26 93.2 0.3 2.6e-26 92.0 0.1 1.8 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 KFR06753.1 - 1.4e-20 73.2 0.1 2.9e-20 72.3 0.1 1.5 1 0 0 1 1 1 1 UBX domain V-set PF07686.17 KFR06754.1 - 1e-11 45.0 0.0 2.3e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFR06754.1 - 4.2e-09 36.9 0.3 1.2e-08 35.5 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFR06754.1 - 8.7e-08 32.1 0.0 1.2e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFR06754.1 - 1.7e-07 31.3 0.0 3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFR06754.1 - 0.0047 17.2 0.2 0.023 15.0 0.0 2.1 2 1 0 2 2 2 1 Immunoglobulin domain DAG1 PF05454.11 KFR06754.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) zf-RRN7 PF11781.8 KFR06754.1 - 0.059 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Adeno_E3_CR2 PF02439.15 KFR06754.1 - 0.062 13.1 0.8 0.12 12.2 0.8 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 KFR06754.1 - 0.12 12.3 0.2 0.23 11.4 0.2 1.5 1 0 0 1 1 1 0 Syndecan domain C1-set PF07654.15 KFR06755.1 - 1.7e-34 118.0 0.2 2.5e-17 63.0 0.1 3.5 4 0 0 4 4 4 2 Immunoglobulin C1-set domain Ig_3 PF13927.6 KFR06755.1 - 8.5e-27 93.6 7.1 1.1e-09 38.8 0.1 3.6 3 1 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFR06755.1 - 1e-20 73.6 1.4 1e-08 35.1 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain C2-set_2 PF08205.12 KFR06755.1 - 2.1e-20 72.6 1.4 5.9e-09 35.9 0.0 3.2 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain ig PF00047.25 KFR06755.1 - 9.8e-20 70.5 1.0 2.2e-06 27.8 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFR06755.1 - 5.5e-18 65.1 0.6 1.7e-05 25.1 0.0 3.7 3 2 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFR06755.1 - 2.8e-16 59.6 0.4 7.5e-12 45.4 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin V-set domain RNA_capsid PF03035.14 KFR06755.1 - 0.022 14.8 0.1 0.036 14.1 0.1 1.3 1 0 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein Ig_6 PF18452.1 KFR06755.1 - 0.1 12.2 0.0 0.53 9.9 0.0 2.2 2 0 0 2 2 2 0 Immunoglobulin domain Lep_receptor_Ig PF06328.11 KFR06755.1 - 0.17 11.8 1.6 5.1 7.1 0.1 3.3 4 1 0 4 4 4 0 Ig-like C2-type domain Pkinase PF00069.25 KFR06756.1 - 1.2e-42 146.2 0.0 6.4e-42 143.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR06756.1 - 3e-25 89.0 0.0 2.6e-22 79.4 0.0 3.4 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KFR06756.1 - 0.0007 19.0 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFR06756.1 - 0.0017 18.3 0.1 0.034 14.0 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFR06756.1 - 0.017 14.5 0.0 0.097 12.0 0.0 2.1 1 1 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KFR06756.1 - 0.033 13.8 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 KFR06756.1 - 0.041 13.4 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PhaC_N PF07167.13 KFR06756.1 - 0.047 13.3 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Pkinase_fungal PF17667.1 KFR06756.1 - 0.049 12.4 0.0 0.063 12.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 KFR06756.1 - 0.15 11.0 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF5581 PF17744.1 KFR06757.1 - 5.3e-122 407.1 7.2 5.9e-122 406.9 7.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5581) fn3 PF00041.21 KFR06757.1 - 0.0083 16.4 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain CopG_antitoxin PF12441.8 KFR06757.1 - 0.1 13.2 0.6 1.7 9.3 0.1 2.3 1 1 1 2 2 2 0 CopG antitoxin of type II toxin-antitoxin system DUF3992 PF13157.6 KFR06757.1 - 0.16 12.7 0.0 0.28 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3992) Fungal_TACC PF12709.7 KFR06757.1 - 0.44 11.0 6.3 0.26 11.8 3.5 2.0 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins AAA_11 PF13086.6 KFR06758.1 - 5.6e-74 249.2 1.9 5.4e-52 177.2 0.2 3.7 2 1 0 3 3 3 3 AAA domain AAA_12 PF13087.6 KFR06758.1 - 8.6e-71 237.7 1.3 1.4e-44 152.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNB PF00773.19 KFR06758.1 - 8.8e-55 186.3 0.0 2.6e-54 184.7 0.0 1.9 1 0 0 1 1 1 1 RNB domain AAA_19 PF13245.6 KFR06758.1 - 4.1e-18 66.1 0.0 2.4e-09 37.7 0.0 3.3 4 0 0 4 4 2 2 AAA domain AAA_30 PF13604.6 KFR06758.1 - 5.1e-18 65.5 0.0 2e-05 24.4 0.0 3.6 3 1 0 3 3 3 3 AAA domain AAA_22 PF13401.6 KFR06758.1 - 1.8e-08 34.8 0.0 0.0019 18.5 0.0 3.6 3 1 0 3 3 2 2 AAA domain ResIII PF04851.15 KFR06758.1 - 4.9e-07 29.9 0.0 0.0095 16.0 0.0 3.0 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KFR06758.1 - 1.4e-06 28.1 0.0 0.0055 16.3 0.0 3.5 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain PhoH PF02562.16 KFR06758.1 - 2.6e-06 27.1 0.2 0.62 9.5 0.0 4.1 4 0 0 4 4 4 2 PhoH-like protein UvrD_C_2 PF13538.6 KFR06758.1 - 9.1e-06 25.4 0.1 0.00079 19.2 0.0 3.1 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 KFR06758.1 - 0.00012 22.6 0.0 0.79 10.1 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain Viral_helicase1 PF01443.18 KFR06758.1 - 0.00015 21.6 4.8 0.0071 16.1 0.0 4.3 3 2 1 5 5 5 1 Viral (Superfamily 1) RNA helicase zf-met PF12874.7 KFR06758.1 - 0.00038 20.7 3.7 0.0016 18.8 3.7 2.2 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF2075 PF09848.9 KFR06758.1 - 0.00045 19.6 0.0 0.0057 15.9 0.0 2.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 KFR06758.1 - 0.0014 19.0 0.1 4.9 7.6 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) UvrD_C PF13361.6 KFR06758.1 - 0.0025 17.2 0.1 2.2 7.6 0.0 2.6 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain T2SSE PF00437.20 KFR06758.1 - 0.0064 15.6 0.2 0.69 8.9 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 KFR06758.1 - 0.021 14.3 0.1 4.7 6.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region DEAD PF00270.29 KFR06758.1 - 0.022 14.5 0.1 1.6 8.4 0.0 2.8 3 0 0 3 3 2 0 DEAD/DEAH box helicase AAA_24 PF13479.6 KFR06758.1 - 0.028 14.1 0.1 1.8 8.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 KFR06758.1 - 0.049 13.6 0.0 18 5.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.18 KFR06758.1 - 0.065 13.1 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein Helicase_RecD PF05127.14 KFR06758.1 - 0.074 12.9 0.0 0.76 9.6 0.0 2.8 3 0 0 3 3 3 0 Helicase Mg_chelatase PF01078.21 KFR06758.1 - 0.086 12.2 0.0 5.5 6.3 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KFR06758.1 - 0.092 12.1 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 KaiC Sigma54_activat PF00158.26 KFR06758.1 - 0.11 12.2 0.0 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain zf-C2H2_jaz PF12171.8 KFR06758.1 - 0.12 12.7 4.4 0.33 11.3 4.4 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding SAND PF01342.21 KFR06759.1 - 3e-24 84.5 0.0 6.3e-24 83.5 0.0 1.5 1 0 0 1 1 1 1 SAND domain Stathmin PF00836.19 KFR06760.1 - 5.6e-50 168.8 15.3 6.9e-50 168.5 15.3 1.1 1 0 0 1 1 1 1 Stathmin family Exonuc_VII_L PF02601.15 KFR06760.1 - 0.78 9.2 4.6 0.8 9.2 4.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TNFR_c6 PF00020.18 KFR06761.1 - 1.4e-23 83.0 44.6 6.4e-09 36.1 9.7 4.5 4 1 0 4 4 4 4 TNFR/NGFR cysteine-rich region Ribosomal_S27 PF01599.19 KFR06761.1 - 0.0039 17.3 0.4 0.0039 17.3 0.4 3.3 3 0 0 3 3 3 1 Ribosomal protein S27a Ephrin_rec_like PF07699.13 KFR06761.1 - 0.015 15.1 7.2 0.015 15.1 7.2 4.8 3 2 2 5 5 5 0 Putative ephrin-receptor like Arf PF00025.21 KFR06762.1 - 2.7e-46 157.2 0.1 3.5e-46 156.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFR06762.1 - 7.8e-15 54.8 0.1 9.9e-15 54.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR06762.1 - 1.9e-14 53.9 0.1 2.6e-14 53.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KFR06762.1 - 3.1e-11 43.1 0.2 7.3e-07 28.7 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KFR06762.1 - 8e-11 41.7 0.0 9.6e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFR06762.1 - 3.5e-08 33.5 0.0 4.8e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFR06762.1 - 1.9e-06 27.4 0.0 2.3e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_18 PF13238.6 KFR06762.1 - 0.08 13.5 0.1 0.14 12.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain G-patch PF01585.23 KFR06763.1 - 2.9e-12 46.3 0.4 7.1e-12 45.0 0.4 1.7 1 0 0 1 1 1 1 G-patch domain zf-CCCH_4 PF18044.1 KFR06763.1 - 1.9e-05 24.3 5.3 2.8e-05 23.8 5.3 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFR06763.1 - 0.00012 22.0 4.0 0.00021 21.2 4.0 1.4 1 0 0 1 1 1 1 Zinc finger domain Agenet PF05641.12 KFR06763.1 - 0.0041 17.6 0.1 0.013 15.9 0.1 1.9 1 0 0 1 1 1 1 Agenet domain Tudor_2 PF18104.1 KFR06763.1 - 0.0053 16.4 0.0 0.016 14.9 0.0 1.8 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain zf-CCCH PF00642.24 KFR06763.1 - 0.046 13.6 3.1 0.074 13.0 3.1 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) G-patch_2 PF12656.7 KFR06763.1 - 0.049 13.7 0.0 0.18 11.9 0.0 2.0 1 0 0 1 1 1 0 G-patch domain MCD_N PF17408.2 KFR06763.1 - 0.68 10.1 2.6 0.81 9.9 0.4 2.2 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain zf-CCCH_2 PF14608.6 KFR06763.1 - 0.83 10.2 7.1 1.3 9.6 7.1 1.3 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger LIME1 PF15332.6 KFR06764.1 - 0.00023 20.9 0.1 0.003 17.2 0.1 2.4 2 1 0 2 2 2 1 Lck-interacting transmembrane adapter 1 PAG PF15347.6 KFR06764.1 - 0.011 14.7 0.1 0.07 12.1 0.0 2.1 1 1 0 2 2 2 0 Phosphoprotein associated with glycosphingolipid-enriched TPD52 PF04201.15 KFR06765.1 - 5.9e-63 211.3 1.2 2.7e-38 131.1 0.5 2.0 1 1 1 2 2 2 2 Tumour protein D52 family HIP1_clath_bdg PF16515.5 KFR06765.1 - 0.15 12.7 3.0 6 7.5 0.5 2.6 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DnaJ PF00226.31 KFR06766.1 - 5.1e-28 97.0 2.5 8.4e-28 96.3 2.5 1.4 1 0 0 1 1 1 1 DnaJ domain Baculo_F PF12259.8 KFR06766.1 - 0.023 13.3 0.0 0.026 13.1 0.0 1.1 1 0 0 1 1 1 0 Baculovirus F protein EMP70 PF02990.16 KFR06766.1 - 0.049 12.3 0.1 0.06 12.0 0.1 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 UPRTase PF14681.6 KFR06767.1 - 9.3e-74 247.3 0.0 1.4e-73 246.8 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.18 KFR06767.1 - 2.2e-59 200.5 0.1 3.1e-59 200.1 0.1 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CPT PF07931.12 KFR06767.1 - 2.8e-07 30.5 0.0 5.4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 KFR06767.1 - 0.0002 21.9 0.0 0.00039 21.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFR06767.1 - 0.0018 18.5 0.0 0.0038 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KFR06767.1 - 0.0076 16.0 0.3 0.72 9.5 0.0 2.3 1 1 0 2 2 2 1 Cytidylate kinase Zeta_toxin PF06414.12 KFR06767.1 - 0.0099 15.2 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin CoaE PF01121.20 KFR06767.1 - 0.013 15.2 0.1 0.07 12.8 0.0 2.0 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_17 PF13207.6 KFR06767.1 - 0.032 14.7 1.2 0.86 10.0 1.1 2.7 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFR06767.1 - 0.034 14.6 0.0 12 6.4 0.0 2.3 2 0 0 2 2 2 0 ABC transporter SAM_2 PF07647.17 KFR06768.1 - 1.5e-17 63.4 0.4 2.2e-17 62.9 0.4 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFR06768.1 - 1.1e-08 35.3 0.2 2e-08 34.5 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFR06768.1 - 1.4e-05 24.9 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PilI PF10623.9 KFR06768.1 - 0.024 14.7 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 Plasmid conjugative transfer protein PilI YdaS_antitoxin PF15943.5 KFR06768.1 - 0.077 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT PRP1_N PF06424.12 KFR06769.1 - 2e-47 161.3 9.5 4.9e-47 160.1 9.5 1.7 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 KFR06769.1 - 7.4e-31 104.2 26.4 0.0019 18.9 0.1 13.6 6 3 9 15 15 14 8 Tetratricopeptide repeat TPR_19 PF14559.6 KFR06769.1 - 3.7e-24 85.0 10.5 9.3e-07 29.3 0.1 9.1 7 2 4 11 11 11 5 Tetratricopeptide repeat TPR_17 PF13431.6 KFR06769.1 - 3.7e-12 45.7 0.7 0.14 12.6 0.0 8.9 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFR06769.1 - 8.8e-10 39.1 12.8 0.00081 20.0 0.0 8.2 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFR06769.1 - 1e-09 37.7 12.3 0.079 13.1 0.0 10.0 11 1 1 12 12 11 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFR06769.1 - 1.1e-07 31.5 0.1 0.34 11.2 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat Suf PF05843.14 KFR06769.1 - 2.9e-07 30.8 1.4 0.098 12.6 0.0 5.5 6 0 0 6 6 6 1 Suppressor of forked protein (Suf) TPR_1 PF00515.28 KFR06769.1 - 2.3e-05 24.0 0.6 0.37 10.7 0.0 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat FAT PF02259.23 KFR06769.1 - 9.7e-05 21.7 15.4 0.1 11.8 1.0 4.6 1 1 3 4 4 4 2 FAT domain TPR_9 PF13371.6 KFR06769.1 - 0.00013 22.1 2.5 19 5.5 0.0 5.7 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 KFR06769.1 - 0.0055 16.4 7.9 0.29 10.8 1.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat-like domain TPR_12 PF13424.6 KFR06769.1 - 0.012 15.9 6.7 29 5.1 0.1 6.3 5 1 0 6 6 6 0 Tetratricopeptide repeat SURF2 PF05477.11 KFR06769.1 - 0.76 9.4 6.2 48 3.5 0.0 2.4 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Toxin_3 PF00537.18 KFR06770.1 - 0.66 10.2 7.1 0.93 9.7 4.0 2.3 2 0 0 2 2 2 0 Scorpion toxin-like domain TFIIS_M PF07500.14 KFR06771.1 - 2.5e-34 118.1 1.1 2.5e-34 118.1 1.1 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KFR06771.1 - 1.6e-18 66.2 8.0 3.4e-18 65.2 8.0 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KFR06771.1 - 7.1e-16 58.0 1.3 7.1e-16 58.0 1.3 2.2 3 0 0 3 3 3 1 TFIIS helical bundle-like domain DBD_Tnp_Mut PF03108.15 KFR06771.1 - 0.0022 17.9 0.2 0.0059 16.6 0.2 1.7 1 0 0 1 1 1 1 MuDR family transposase AIM3 PF17096.5 KFR06771.1 - 0.1 13.5 2.5 0.27 12.2 2.5 1.7 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 7tm_1 PF00001.21 KFR06772.1 - 4.7e-64 216.3 17.9 7.1e-64 215.7 17.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR06772.1 - 9.6e-14 51.4 18.9 1.5e-13 50.7 18.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 KFR06772.1 - 3.6e-08 33.1 7.4 3.6e-08 33.1 7.4 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFR06772.1 - 7e-08 32.5 16.0 5.3e-07 29.6 16.0 1.9 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFR06772.1 - 1e-06 28.6 20.3 1.1e-06 28.5 18.3 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4381 PF14316.6 KFR06772.1 - 0.25 11.6 0.0 0.52 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) zf-C2HC PF01530.18 KFR06773.1 - 4.3e-99 324.3 97.1 1.1e-15 57.5 7.2 7.6 7 0 0 7 7 7 7 Zinc finger, C2HC type MYT1 PF08474.11 KFR06773.1 - 7.3e-78 261.8 17.2 3.5e-52 177.8 12.1 4.8 3 2 1 4 4 4 2 Myelin transcription factor 1 DUF1664 PF07889.12 KFR06773.1 - 0.14 12.2 3.0 0.33 11.0 3.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) IBR PF01485.21 KFR06773.1 - 0.27 11.5 28.2 11 6.3 0.3 8.0 6 2 2 8 8 8 0 IBR domain, a half RING-finger domain XhlA PF10779.9 KFR06773.1 - 4.6 7.5 7.9 22 5.4 7.9 2.2 1 1 0 1 1 1 0 Haemolysin XhlA Ly49 PF08391.10 KFR06773.1 - 6.3 7.2 8.0 16 5.9 0.0 3.0 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region PCMT PF01135.19 KFR06774.1 - 2.1e-26 93.0 0.0 2.9e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SOCS_box PF07525.16 KFR06774.1 - 2.2e-05 24.7 5.9 0.096 13.1 0.0 2.5 2 0 0 2 2 2 2 SOCS box DOT1 PF08123.13 KFR06774.1 - 0.00018 21.1 0.0 0.00031 20.3 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 KFR06774.1 - 0.0011 18.8 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFR06774.1 - 0.011 16.5 1.3 0.08 13.7 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain GCD14 PF08704.10 KFR06774.1 - 0.014 15.1 0.3 0.031 14.0 0.0 1.7 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_25 PF13649.6 KFR06774.1 - 0.016 15.9 0.0 0.13 13.0 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain REV PF00424.18 KFR06774.1 - 0.02 14.9 0.7 0.039 14.0 0.7 1.5 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) An_peroxidase PF03098.15 KFR06775.1 - 2.9e-199 663.0 0.0 4.2e-199 662.5 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase I-set PF07679.16 KFR06775.1 - 2.1e-84 277.7 0.0 1e-20 73.5 0.0 4.3 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR06775.1 - 7.3e-71 234.8 0.4 5.1e-17 62.2 0.1 4.4 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFR06775.1 - 4.3e-48 161.6 0.0 2.5e-11 43.7 0.0 4.5 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 KFR06775.1 - 1.4e-36 124.5 0.0 9.5e-09 35.3 0.1 4.4 4 0 0 4 4 4 4 Immunoglobulin domain LRR_8 PF13855.6 KFR06775.1 - 6.2e-36 122.0 25.9 8.2e-17 60.7 5.5 3.6 1 1 2 3 3 3 3 Leucine rich repeat V-set PF07686.17 KFR06775.1 - 4e-24 84.9 4.7 0.00046 20.3 0.2 8.0 4 4 0 4 4 4 4 Immunoglobulin V-set domain LRR_4 PF12799.7 KFR06775.1 - 2.4e-15 56.4 22.7 7.8e-06 26.1 0.4 5.0 6 0 0 6 6 4 3 Leucine Rich repeats (2 copies) C2-set_2 PF08205.12 KFR06775.1 - 2.9e-14 52.9 0.1 0.021 14.9 0.0 4.5 4 0 0 4 4 4 4 CD80-like C2-set immunoglobulin domain LRR_5 PF13306.6 KFR06775.1 - 5.4e-13 49.0 1.1 1.4e-12 47.7 1.1 1.7 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) Ig_5 PF16681.5 KFR06775.1 - 5.8e-10 39.4 0.0 0.0082 16.5 0.0 4.8 5 0 0 5 5 5 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain LRR_9 PF14580.6 KFR06775.1 - 2.8e-09 36.7 5.4 5.9e-05 22.6 1.9 2.3 1 1 1 2 2 2 2 Leucine-rich repeat Ig_4 PF16680.5 KFR06775.1 - 2.5e-08 34.1 0.0 0.015 15.5 0.1 4.6 4 0 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFR06775.1 - 2.6e-05 23.7 0.0 0.24 11.0 0.0 4.1 4 0 0 4 4 4 2 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFR06775.1 - 3.6e-05 23.7 0.0 0.83 9.7 0.0 4.6 5 0 0 5 5 5 1 C17orf99 Ig domain Izumo-Ig PF16706.5 KFR06775.1 - 0.00018 21.5 0.1 21 5.3 0.0 4.6 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain LRRCT PF01463.24 KFR06775.1 - 0.0074 16.8 0.0 0.026 15.0 0.0 2.1 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain DUF1997 PF09366.10 KFR06775.1 - 0.012 15.8 0.1 0.082 13.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1997) LRRNT PF01462.18 KFR06775.1 - 0.16 11.7 3.3 0.56 9.9 3.3 2.1 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain B_lectin PF01453.24 KFR06775.1 - 0.2 12.2 0.4 21 5.7 0.1 3.4 4 0 0 4 4 3 0 D-mannose binding lectin Pkinase_Tyr PF07714.17 KFR06776.1 - 4.4e-94 314.6 0.0 5.6e-94 314.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR06776.1 - 2.4e-48 164.8 0.0 3.1e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFR06776.1 - 3.6e-23 81.4 0.0 8.3e-23 80.3 0.0 1.7 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 KFR06776.1 - 1.2e-08 34.7 0.0 2.6e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFR06776.1 - 2.3e-06 27.1 0.0 4.1e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Haspin_kinase PF12330.8 KFR06776.1 - 6.4e-06 25.3 0.1 1.5e-05 24.1 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KFR06776.1 - 0.00041 20.0 0.1 0.00068 19.3 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KFR06776.1 - 0.0031 16.9 0.0 0.005 16.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFR06776.1 - 0.011 15.1 0.4 0.027 13.8 0.4 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_2 PF07653.17 KFR06776.1 - 0.13 11.9 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain Pkinase_fungal PF17667.1 KFR06776.1 - 0.2 10.4 0.1 0.27 10.0 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase PPDFL PF15060.6 KFR06777.1 - 4e-44 149.6 3.5 4.3e-44 149.5 3.5 1.0 1 0 0 1 1 1 1 Differentiation and proliferation regulator GTP_EFTU PF00009.27 KFR06778.1 - 2.4e-55 187.1 0.0 3.4e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFR06778.1 - 3.8e-40 136.7 0.0 8.2e-40 135.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KFR06778.1 - 7.9e-15 55.0 1.4 1.5e-14 54.1 0.4 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFR06778.1 - 0.00033 20.7 0.2 0.0084 16.2 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KFR06778.1 - 0.018 15.0 0.7 0.047 13.6 0.1 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Dynamin_N PF00350.23 KFR06778.1 - 0.039 14.0 0.1 10 6.1 0.0 2.4 2 0 0 2 2 2 0 Dynamin family G-alpha PF00503.20 KFR06778.1 - 0.19 10.9 0.4 0.53 9.4 0.1 1.8 2 0 0 2 2 2 0 G-protein alpha subunit KCNQ_channel PF03520.14 KFR06779.1 - 1.5e-83 279.3 0.0 5.9e-83 277.4 0.0 1.9 1 1 0 1 1 1 1 KCNQ voltage-gated potassium channel KCNQC3-Ank-G_bd PF11956.8 KFR06779.1 - 5.1e-46 155.2 1.0 1e-45 154.2 1.0 1.5 1 0 0 1 1 1 1 Ankyrin-G binding motif of KCNQ2-3 KCNQ2_u3 PF16642.5 KFR06779.1 - 2.7e-36 124.5 11.9 2.7e-36 124.5 11.9 2.5 3 0 0 3 3 3 1 Unstructured region on Potassium channel subunit alpha KvLQT2 Ion_trans PF00520.31 KFR06779.1 - 1.8e-29 102.7 5.7 3e-29 102.0 5.7 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFR06779.1 - 2e-13 50.1 3.1 5.3e-13 48.7 3.1 1.7 1 0 0 1 1 1 1 Ion channel Neur_chan_LBD PF02931.23 KFR06780.1 - 2.8e-76 255.7 4.2 3.3e-76 255.5 4.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFR06780.1 - 3.5e-62 210.6 17.2 4.7e-62 210.2 17.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Claudin_2 PF13903.6 KFR06780.1 - 0.067 12.9 1.8 0.27 11.0 0.8 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2417 PF10329.9 KFR06780.1 - 0.11 11.8 8.3 0.21 11.0 8.3 1.4 1 0 0 1 1 1 0 Region of unknown function (DUF2417) fn3 PF00041.21 KFR06781.1 - 3.8e-77 254.7 15.9 2.9e-15 56.4 0.4 6.4 6 0 0 6 6 6 6 Fibronectin type III domain VWA PF00092.28 KFR06781.1 - 3.5e-49 167.4 0.5 9e-49 166.1 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain Collagen PF01391.18 KFR06781.1 - 3.9e-39 132.2 152.1 1.8e-09 37.2 35.3 5.3 2 2 3 5 5 5 5 Collagen triple helix repeat (20 copies) VWA_2 PF13519.6 KFR06781.1 - 2.1e-13 50.9 0.0 5e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Pur_ac_phosph_N PF16656.5 KFR06781.1 - 2.2e-07 31.4 15.0 0.42 11.2 0.0 7.2 5 2 0 5 5 5 3 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 KFR06781.1 - 9.8e-07 29.1 0.8 2.4 8.6 0.0 6.2 6 0 0 6 6 6 1 Uncharacterised conserved protein (DUF2369) CBM_4_9 PF02018.17 KFR06781.1 - 0.00011 22.5 1.5 0.0045 17.3 0.0 3.3 4 0 0 4 4 4 1 Carbohydrate binding domain DUF4959 PF16323.5 KFR06781.1 - 0.00071 19.9 0.5 1.8 8.9 0.0 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF4959) DUF4998 PF16389.5 KFR06781.1 - 0.0021 17.7 0.0 0.22 11.1 0.0 3.6 5 0 0 5 5 5 1 Domain of unknown function ASH PF15780.5 KFR06781.1 - 0.13 12.5 0.3 13 6.0 0.1 2.8 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DEP PF00610.21 KFR06782.1 - 1.1e-44 150.3 1.1 3.7e-22 78.2 0.1 2.3 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ_6 PF17820.1 KFR06782.1 - 1.5e-07 31.1 0.0 2.7e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFR06782.1 - 0.049 14.0 0.0 0.082 13.3 0.0 1.4 1 0 0 1 1 1 0 PDZ domain PDZ_2 PF13180.6 KFR06782.1 - 0.056 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 PDZ domain ArfGap PF01412.18 KFR06783.1 - 8.1e-33 113.0 0.5 8.1e-33 113.0 0.5 2.7 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf zf-piccolo PF05715.13 KFR06783.1 - 0.026 14.7 1.4 0.073 13.2 1.4 1.7 1 0 0 1 1 1 0 Piccolo Zn-finger Ribosomal_L37ae PF01780.19 KFR06783.1 - 0.045 13.8 0.2 0.12 12.4 0.2 1.8 1 0 0 1 1 1 0 Ribosomal L37ae protein family NKAIN PF05640.14 KFR06784.1 - 3.5e-92 307.4 6.4 4e-92 307.2 6.4 1.0 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein DUF1003 PF06210.11 KFR06784.1 - 0.11 12.6 1.4 0.22 11.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) BIR PF00653.21 KFR06785.1 - 2.3e-43 146.7 11.3 4.6e-23 81.7 0.5 2.8 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 KFR06785.1 - 2.6e-14 52.8 7.0 2.6e-14 52.8 7.0 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFR06785.1 - 8.9e-06 25.5 6.8 8.9e-06 25.5 6.8 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KFR06785.1 - 0.0013 19.1 8.2 0.0013 19.1 8.2 2.6 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFR06785.1 - 0.0032 17.3 6.0 0.0032 17.3 6.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) GAGA PF09237.11 KFR06785.1 - 0.063 13.1 0.9 0.17 11.8 0.9 1.7 1 0 0 1 1 1 0 GAGA factor DUF2039 PF10217.9 KFR06785.1 - 0.066 13.6 2.2 0.13 12.6 2.2 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) YTH PF04146.15 KFR06786.1 - 4.1e-42 143.9 0.4 1.2e-41 142.4 0.4 1.8 1 1 0 1 1 1 1 YT521-B-like domain Ig_2 PF13895.6 KFR06811.1 - 1.6e-06 28.3 0.0 1.8e-06 28.2 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFR06811.1 - 8.7e-06 25.7 0.0 1e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR06811.1 - 1.6e-05 25.4 0.1 1.9e-05 25.1 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFR06811.1 - 0.00079 19.6 0.2 0.0012 19.0 0.1 1.4 1 1 1 2 2 2 1 Immunoglobulin V-set domain ig PF00047.25 KFR06811.1 - 0.00085 19.5 0.2 0.0011 19.1 0.2 1.4 1 1 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 KFR06811.1 - 0.0014 18.2 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFR06811.1 - 0.011 15.8 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain TIR PF01582.20 KFR06814.1 - 3.1e-28 98.7 0.0 4.7e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 KFR06814.1 - 8.6e-07 29.6 0.0 1.6e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 TIR domain ig PF00047.25 KFR06814.1 - 1.8e-06 28.0 0.0 3.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFR06814.1 - 4.1e-06 27.3 0.0 8.8e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFR06814.1 - 9.9e-06 25.5 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFR06814.1 - 0.0008 19.7 0.0 0.0023 18.2 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin domain DUF4569 PF15133.6 KFR06815.1 - 1.6e-105 353.1 7.7 1.8e-105 353.0 7.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4569) Mfa1 PF17445.2 KFR06815.1 - 2.1 8.4 4.9 1.5 8.9 0.3 2.6 3 0 0 3 3 3 0 Mating factor A1 Cofac_haem_bdg PF04187.13 KFR06816.1 - 0.084 12.9 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN FGGY_N PF00370.21 KFR06817.1 - 7.2e-76 255.0 0.0 1e-75 254.5 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KFR06817.1 - 5.7e-65 218.8 0.6 1.1e-64 217.9 0.4 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Ceramidase_alk PF04734.13 KFR06817.1 - 0.21 10.2 1.7 11 4.5 0.0 2.6 3 0 0 3 3 3 0 Neutral/alkaline non-lysosomal ceramidase, N-terminal CUE PF02845.16 KFR06818.1 - 1.1e-09 37.8 0.2 3e-09 36.4 0.2 1.8 2 0 0 2 2 2 1 CUE domain zf-RanBP PF00641.18 KFR06818.1 - 5.7e-05 22.4 1.7 5.7e-05 22.4 1.7 1.8 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others HALZ PF02183.18 KFR06819.1 - 0.0024 18.1 8.8 0.085 13.1 3.8 2.4 2 0 0 2 2 2 2 Homeobox associated leucine zipper APG6_N PF17675.1 KFR06819.1 - 0.0052 17.3 0.8 0.0089 16.6 0.8 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region LRRFIP PF09738.9 KFR06819.1 - 0.016 14.7 1.1 0.017 14.6 1.1 1.4 1 0 0 1 1 1 0 LRRFIP family YabA PF06156.13 KFR06819.1 - 0.043 14.4 2.4 0.11 13.2 1.3 2.0 2 0 0 2 2 2 0 Initiation control protein YabA bZIP_1 PF00170.21 KFR06819.1 - 0.1 12.7 0.9 0.1 12.7 0.9 2.1 2 0 0 2 2 2 0 bZIP transcription factor Nnf1 PF03980.14 KFR06819.1 - 0.18 12.2 4.7 0.2 12.1 3.4 1.9 2 1 0 2 2 2 0 Nnf1 SOGA PF11365.8 KFR06819.1 - 0.19 12.9 4.8 0.077 14.1 1.9 1.9 2 1 0 2 2 2 0 Protein SOGA ZapB PF06005.12 KFR06819.1 - 0.52 10.8 10.5 1.7 9.1 4.8 2.5 3 0 0 3 3 3 0 Cell division protein ZapB GIT_CC PF16559.5 KFR06819.1 - 2.1 8.2 6.3 0.58 10.1 1.9 2.2 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1043 PF06295.12 KFR06819.1 - 2.5 8.1 6.1 0.33 10.9 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DMPK_coil PF08826.10 KFR06819.1 - 8.5 6.6 10.6 3.4 7.8 3.9 2.9 3 1 1 4 4 4 0 DMPK coiled coil domain like PMP22_Claudin PF00822.20 KFR06820.1 - 5.3e-06 26.4 5.8 6.7e-06 26.1 5.8 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.11 KFR06820.1 - 0.0031 17.5 9.0 0.0067 16.4 9.0 1.5 1 1 0 1 1 1 1 Tight junction protein, Claudin-like Clc-like PF07062.12 KFR06820.1 - 0.0073 15.8 10.4 0.031 13.8 0.5 2.1 1 1 1 2 2 2 2 Clc-like ApoO PF09769.9 KFR06820.1 - 0.15 12.0 0.1 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 Apolipoprotein O Claudin_2 PF13903.6 KFR06820.1 - 0.85 9.3 16.1 0.048 13.4 10.2 1.8 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Yip1 PF04893.17 KFR06820.1 - 0.92 9.2 14.3 1.8 8.3 14.3 1.5 1 1 0 1 1 1 0 Yip1 domain DUF2721 PF11026.8 KFR06820.1 - 5.7 6.8 9.9 0.85 9.5 4.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Glu_cys_ligase PF04262.14 KFR06823.1 - 0.12 11.0 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase ASH PF15780.5 KFR06824.1 - 0.0086 16.3 0.0 0.012 15.8 0.0 1.3 1 1 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 KFR06824.1 - 0.0098 16.1 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 131-like Gal-bind_lectin PF00337.22 KFR06826.1 - 0.032 13.8 0.0 0.062 12.8 0.0 1.5 1 1 0 1 1 1 0 Galactoside-binding lectin Arrestin_N PF00339.29 KFR06826.1 - 0.12 12.4 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain ASH PF15780.5 KFR06827.1 - 2.1e-11 43.9 2.2 0.02 15.1 0.1 5.6 5 1 1 6 6 6 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 KFR06827.1 - 3.7e-07 30.0 1.2 0.19 11.6 0.1 4.4 4 0 0 4 4 4 2 MSP (Major sperm protein) domain TMEM131_like PF12371.8 KFR06827.1 - 7.8e-06 26.1 1.1 6.2e-05 23.2 0.1 2.8 2 0 0 2 2 2 1 Transmembrane protein 131-like LANC_like PF05147.13 KFR06829.1 - 1.7e-57 194.6 0.0 2.1e-57 194.3 0.0 1.0 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein C5-epim_C PF06662.13 KFR06829.1 - 0.021 14.3 1.0 1.7 8.1 0.2 2.3 1 1 1 2 2 2 0 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_127 PF07944.12 KFR06829.1 - 0.08 11.4 0.0 0.34 9.3 0.0 1.6 1 1 1 2 2 2 0 Beta-L-arabinofuranosidase, GH127 NAD_binding_6 PF08030.12 KFR06830.1 - 4.6e-37 127.5 0.0 7.6e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KFR06830.1 - 6e-25 87.8 6.8 6e-25 87.8 6.8 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFR06830.1 - 6.6e-22 77.7 0.2 1.6e-21 76.4 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain FAD_binding_6 PF00970.24 KFR06830.1 - 0.00013 22.2 0.0 0.00027 21.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KFR06830.1 - 0.018 15.6 0.0 0.082 13.6 0.0 2.0 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Tctex-1 PF03645.13 KFR06831.1 - 1.5e-31 108.7 2.7 1.6e-31 108.6 2.7 1.0 1 0 0 1 1 1 1 Tctex-1 family C2 PF00168.30 KFR06832.1 - 1e-43 147.8 0.3 3.1e-22 78.8 0.1 2.4 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.16 KFR06832.1 - 3.6e-18 65.9 9.9 6.3e-18 65.1 9.9 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger PI3K_C2 PF00792.24 KFR06832.1 - 0.0052 16.7 0.3 0.095 12.6 0.1 2.3 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 Rubredoxin_2 PF18073.1 KFR06832.1 - 0.62 9.8 3.1 2 8.2 3.1 1.8 1 0 0 1 1 1 0 Rubredoxin metal binding domain zf-B_box PF00643.24 KFR06832.1 - 6.7 7.0 12.3 6.9 6.9 2.8 2.7 3 0 0 3 3 3 0 B-box zinc finger C1_1 PF00130.22 KFR06832.1 - 7.3 6.6 12.4 4.4 7.3 8.6 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4174 PF13778.6 KFR06833.1 - 5.5e-31 107.5 0.0 7.5e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) HYR PF02494.16 KFR06833.1 - 1e-28 99.5 0.0 1.8e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 HYR domain Sushi PF00084.20 KFR06833.1 - 7.4e-25 87.3 26.8 5e-11 43.0 3.9 3.4 3 0 0 3 3 3 3 Sushi repeat (SCR repeat) RCC1 PF00415.18 KFR06834.1 - 1.7e-74 246.3 17.2 8.6e-13 48.7 0.1 8.1 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFR06834.1 - 2.3e-41 138.8 21.1 1.7e-08 34.0 0.1 8.1 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Kelch_4 PF13418.6 KFR06834.1 - 0.0042 17.1 6.4 1.5 8.9 0.1 4.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 KFR06834.1 - 0.007 16.3 0.2 7.6 6.7 0.0 3.3 3 0 0 3 3 3 2 Kelch motif DUF1921 PF09081.10 KFR06834.1 - 0.11 12.8 0.0 1.3 9.3 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1921) OTCace PF00185.24 KFR06835.1 - 8.6e-52 175.4 0.0 1.2e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 KFR06835.1 - 5.1e-43 146.6 0.0 9.6e-43 145.7 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Tetraspanin PF00335.20 KFR06836.1 - 2.2e-43 148.6 5.6 2.4e-43 148.5 5.6 1.0 1 0 0 1 1 1 1 Tetraspanin family Spot_14 PF07084.12 KFR06837.1 - 3.5e-31 108.4 0.0 4.1e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Thyroid hormone-inducible hepatic protein Spot 14 NUDIX PF00293.28 KFR06840.1 - 0.046 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 NUDIX domain DUF2469 PF10611.9 KFR06894.1 - 0.002 18.7 0.3 0.01 16.4 0.1 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2469) TGS PF02824.21 KFR06894.1 - 0.0028 17.7 0.0 0.0099 15.9 0.0 1.9 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.14 KFR06894.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Threonyl and Alanyl tRNA synthetase second additional domain Ig_3 PF13927.6 KFR06895.1 - 1.9e-20 73.2 1.0 7.5e-14 52.1 0.5 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFR06895.1 - 1.1e-16 60.6 0.2 5.4e-10 39.2 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFR06895.1 - 2.2e-16 59.8 3.4 9e-09 35.4 0.2 2.7 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 KFR06895.1 - 8.5e-16 58.1 1.0 3.2e-07 30.5 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 KFR06895.1 - 1.2e-12 48.0 5.2 1.1e-09 38.5 0.5 2.7 3 0 0 3 3 3 2 Immunoglobulin domain Ig_6 PF18452.1 KFR06895.1 - 3.6e-06 26.4 0.0 0.002 17.6 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFR06895.1 - 5.4e-06 26.3 0.0 6.2e-05 23.0 0.0 2.5 2 1 0 2 2 2 1 C17orf99 Ig domain Izumo-Ig PF16706.5 KFR06895.1 - 0.00034 20.6 0.2 0.17 11.9 0.0 2.6 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain DUF4307 PF14155.6 KFR06895.1 - 0.00095 19.0 0.7 0.19 11.6 0.2 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4307) Ig_4 PF16680.5 KFR06895.1 - 0.0049 17.1 4.0 8.3 6.7 0.2 3.9 4 1 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFR06895.1 - 0.0099 15.9 0.1 0.021 14.9 0.1 1.6 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.8 KFR06895.1 - 0.023 14.9 0.1 8.1 6.7 0.0 2.9 2 1 0 2 2 2 0 Natural killer cell receptor 2B4 ATP-synt_F6 PF05511.11 KFR06896.1 - 3.3e-45 152.5 0.1 3.7e-45 152.3 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 Ets PF00178.22 KFR06897.1 - 8.8e-34 115.8 0.3 2e-33 114.7 0.3 1.6 1 0 0 1 1 1 1 Ets-domain GABP-alpha PF11620.8 KFR06897.1 - 6.6e-32 109.6 0.8 1.3e-31 108.6 0.8 1.5 1 0 0 1 1 1 1 GA-binding protein alpha chain SAM_PNT PF02198.16 KFR06897.1 - 5.2e-28 96.8 0.2 1.6e-27 95.3 0.2 1.9 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Syntaxin-18_N PF10496.9 KFR06897.1 - 0.16 12.2 0.0 0.4 11.0 0.0 1.6 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus RVT_1 PF00078.27 KFR06898.1 - 0.0021 17.6 0.0 0.0058 16.2 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) APP_E2 PF12925.7 KFR06899.1 - 2.6e-73 245.8 19.9 4.6e-73 245.0 19.9 1.4 1 0 0 1 1 1 1 E2 domain of amyloid precursor protein APP_N PF02177.16 KFR06899.1 - 1.3e-44 150.6 0.5 1.3e-44 150.6 0.5 2.4 2 0 0 2 2 2 1 Amyloid A4 N-terminal heparin-binding APP_Cu_bd PF12924.7 KFR06899.1 - 2.3e-26 92.3 4.9 2.3e-26 92.3 4.9 2.4 3 0 0 3 3 3 1 Copper-binding of amyloid precursor, CuBD APP_amyloid PF10515.9 KFR06899.1 - 1.2e-25 89.8 0.3 5.2e-25 87.7 0.3 2.2 1 0 0 1 1 1 1 Beta-amyloid precursor protein C-terminus Beta-APP PF03494.13 KFR06899.1 - 1.9e-23 82.0 1.0 3.4e-23 81.2 1.0 1.4 1 0 0 1 1 1 1 Beta-amyloid peptide (beta-APP) Kunitz_BPTI PF00014.23 KFR06899.1 - 1.8e-19 69.7 6.2 3.8e-19 68.7 6.2 1.6 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Insulin_TMD PF17870.1 KFR06899.1 - 0.16 12.1 1.0 0.33 11.1 1.0 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment PilJ PF13675.6 KFR06899.1 - 1.9 8.5 5.9 1.6 8.8 3.1 2.3 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Bcl-2 PF00452.19 KFR06899.1 - 2.1 9.1 4.2 5.5 7.7 0.1 3.2 2 1 0 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family Activator-TraM PF11657.8 KFR06899.1 - 4.2 7.2 11.1 0.49 10.2 5.9 2.0 2 0 0 2 2 2 0 Transcriptional activator TraM CYYR1 PF10873.8 KFR06900.1 - 1.6e-49 168.2 16.7 1.7e-49 168.1 16.7 1.0 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 Podoplanin PF05808.11 KFR06900.1 - 0.91 9.6 5.1 1.3 9.1 5.1 1.2 1 0 0 1 1 1 0 Podoplanin ADAM_spacer1 PF05986.14 KFR06901.1 - 3.8e-32 110.7 0.0 6.3e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 ADAM_CR_2 PF17771.1 KFR06901.1 - 9.6e-26 90.1 24.3 1.2e-22 80.2 9.7 4.2 3 1 0 3 3 3 2 ADAM cysteine-rich domain Reprolysin PF01421.19 KFR06901.1 - 9.5e-20 71.3 0.0 1.5e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease TSP_1 PF00090.19 KFR06901.1 - 2e-15 56.7 49.6 6e-09 36.0 6.6 6.3 6 0 0 6 6 6 3 Thrombospondin type 1 domain Reprolysin_5 PF13688.6 KFR06901.1 - 1.2e-12 48.4 0.2 2.3e-12 47.5 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFR06901.1 - 4.2e-11 43.4 0.0 8.1e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFR06901.1 - 0.00038 20.1 0.1 0.00064 19.4 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFR06901.1 - 0.00045 20.2 0.1 0.00092 19.2 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like CxC6 PF18721.1 KFR06901.1 - 0.011 15.9 3.1 0.011 15.9 3.1 3.7 4 0 0 4 4 4 0 CxC6 like cysteine cluster associated with KDZ transposases Atracotoxin PF05353.11 KFR06902.1 - 0.051 13.6 10.0 0.092 12.8 10.0 1.6 1 0 0 1 1 1 0 Delta Atracotoxin ADAM_spacer1 PF05986.14 KFR06903.1 - 1.4e-33 115.3 0.1 2.1e-33 114.8 0.1 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 ADAM_CR_2 PF17771.1 KFR06903.1 - 4.1e-22 78.5 14.2 1.5e-20 73.5 5.9 5.3 6 0 0 6 6 5 2 ADAM cysteine-rich domain Reprolysin PF01421.19 KFR06903.1 - 3.5e-21 76.0 0.1 7.4e-21 75.0 0.1 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.6 KFR06903.1 - 1e-12 48.7 0.9 2.8e-12 47.3 0.9 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFR06903.1 - 2.2e-11 44.3 0.8 4.9e-11 43.2 0.8 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 TSP_1 PF00090.19 KFR06903.1 - 5.9e-10 39.2 6.4 5.9e-10 39.2 6.4 4.2 4 0 0 4 4 3 2 Thrombospondin type 1 domain Reprolysin_2 PF13574.6 KFR06903.1 - 2.1e-06 27.8 0.4 5.5e-06 26.4 0.4 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFR06903.1 - 7.4e-06 25.7 0.4 1.5e-05 24.7 0.4 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFR06903.1 - 0.0013 18.6 0.4 0.0029 17.5 0.4 1.6 1 0 0 1 1 1 1 Matrixin Astacin PF01400.24 KFR06903.1 - 0.018 14.7 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) DUF3285 PF11688.8 KFR06903.1 - 0.026 14.4 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) DUF4953 PF16313.5 KFR06903.1 - 0.061 12.5 0.5 0.13 11.5 0.5 1.4 1 0 0 1 1 1 0 Met-zincin Peptidase_M54 PF07998.11 KFR06903.1 - 0.088 12.8 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M54 CxC6 PF18721.1 KFR06903.1 - 0.98 9.7 14.1 0.038 14.3 4.8 3.3 2 0 0 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases MTS PF05175.14 KFR06904.1 - 1.1e-06 28.3 0.0 2e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 KFR06904.1 - 0.0004 19.9 0.0 0.0026 17.2 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KFR06904.1 - 0.0066 16.2 0.0 0.093 12.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFR06904.1 - 0.011 16.4 0.0 0.019 15.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 KFR06904.1 - 0.062 13.0 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_12 PF08242.12 KFR06904.1 - 0.099 13.4 0.1 0.21 12.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_24 PF13578.6 KFR06904.1 - 0.12 13.4 0.0 0.22 12.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DUF1115 PF06544.12 KFR06905.1 - 3.3e-18 66.2 0.1 1.7e-17 63.9 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) RWD PF05773.22 KFR06905.1 - 4.5e-15 56.0 0.6 8e-15 55.1 0.6 1.4 1 0 0 1 1 1 1 RWD domain UCH PF00443.29 KFR06906.1 - 1e-52 179.2 0.8 3.1e-52 177.6 0.8 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFR06906.1 - 7.9e-21 74.2 9.4 7.9e-21 74.2 9.4 2.3 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein MMR_HSR1 PF01926.23 KFR06906.1 - 0.0049 16.9 1.5 0.041 14.0 0.0 2.9 2 2 1 3 3 3 1 50S ribosome-binding GTPase zinc_ribbon_10 PF10058.9 KFR06906.1 - 0.61 9.8 4.5 0.71 9.6 0.5 2.8 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Cpn60_TCP1 PF00118.24 KFR06907.1 - 1.8e-153 511.7 6.2 2.1e-153 511.5 6.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family APG6_N PF17675.1 KFR06908.1 - 0.0013 19.2 10.1 0.0013 19.2 10.1 1.4 2 0 0 2 2 1 1 Apg6 coiled-coil region FTA4 PF13093.6 KFR06908.1 - 0.027 14.4 4.2 0.029 14.2 4.2 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 GAS PF13851.6 KFR06908.1 - 0.043 13.2 13.8 0.058 12.7 13.8 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding GIT_CC PF16559.5 KFR06908.1 - 0.11 12.4 3.3 0.22 11.4 3.3 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor CENP-H PF05837.12 KFR06908.1 - 0.19 12.1 13.2 4.8 7.6 13.3 2.2 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Spc24 PF08286.11 KFR06908.1 - 0.23 11.7 10.5 4.2 7.7 10.5 2.2 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 CCDC-167 PF15188.6 KFR06908.1 - 0.24 11.8 11.6 0.46 10.9 11.6 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 SLATT_5 PF18160.1 KFR06908.1 - 0.36 10.1 4.8 0.51 9.6 4.8 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 DASH_Spc19 PF08287.11 KFR06908.1 - 0.37 10.7 10.2 0.56 10.1 10.2 1.3 1 0 0 1 1 1 0 Spc19 Takusan PF04822.13 KFR06908.1 - 0.85 9.5 8.7 1.5 8.7 8.7 1.5 1 0 0 1 1 1 0 Takusan Seryl_tRNA_N PF02403.22 KFR06908.1 - 2.5 8.3 10.1 4.3 7.6 10.1 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain bZIP_2 PF07716.15 KFR06908.1 - 3.2 7.9 14.6 2.6 8.2 2.3 2.4 2 0 0 2 2 2 0 Basic region leucine zipper ZapB PF06005.12 KFR06908.1 - 3.7 8.1 17.3 14 6.2 9.0 2.4 1 1 1 2 2 2 0 Cell division protein ZapB UPF0242 PF06785.11 KFR06908.1 - 4.7 7.3 15.2 11 6.1 15.2 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 KFR06908.1 - 4.9 7.8 9.9 2.9 8.6 4.7 2.1 1 1 1 2 2 2 0 Initiation control protein YabA bZIP_1 PF00170.21 KFR06908.1 - 7.6 6.7 14.1 1.4 9.1 2.5 2.6 2 1 1 3 3 3 0 bZIP transcription factor BTB PF00651.31 KFR06909.1 - 9.5e-25 87.0 0.5 2.2e-24 85.8 0.5 1.6 1 0 0 1 1 1 1 BTB/POZ domain bZIP_Maf PF03131.17 KFR06909.1 - 8.8e-16 58.2 5.6 2.3e-15 56.9 5.6 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 KFR06909.1 - 1.2e-09 38.1 8.1 2.9e-09 36.9 8.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFR06909.1 - 6.7e-07 29.3 9.1 1.6e-06 28.1 9.1 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Seryl_tRNA_N PF02403.22 KFR06909.1 - 0.21 11.8 3.5 0.64 10.3 3.5 1.8 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ANF_receptor PF01094.28 KFR06910.1 - 5.7e-74 249.3 0.0 7.9e-74 248.9 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 KFR06910.1 - 7.3e-54 181.7 0.1 1.2e-53 181.0 0.1 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFR06910.1 - 1.2e-46 157.6 0.0 4.6e-46 155.7 0.0 2.0 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFR06910.1 - 2.3e-19 69.8 0.0 5.4e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.6 KFR06910.1 - 1.8e-06 27.9 0.0 3.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein Tiam_CC_Ex PF18385.1 KFR06911.1 - 2.9e-57 191.1 0.2 6.9e-57 189.9 0.2 1.7 1 0 0 1 1 1 1 T-lymphoma invasion and metastasis CC-Ex domain RhoGEF PF00621.20 KFR06911.1 - 7.5e-41 140.4 2.3 7.5e-41 140.4 2.3 1.9 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 KFR06911.1 - 6.6e-27 94.1 2.8 7.3e-15 55.4 0.4 3.4 3 0 0 3 3 3 2 PH domain RBD PF02196.15 KFR06911.1 - 9.6e-17 60.8 0.0 2.3e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Raf-like Ras-binding domain PH_9 PF15410.6 KFR06911.1 - 7e-11 42.5 0.3 1.9e-10 41.1 0.3 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PDZ PF00595.24 KFR06911.1 - 5e-07 30.0 0.0 1.2e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFR06911.1 - 0.00036 20.3 0.0 0.00082 19.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFR06911.1 - 0.00048 20.4 0.0 0.0014 18.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PH_11 PF15413.6 KFR06911.1 - 0.00083 19.7 0.3 0.0089 16.4 0.4 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain AAA_22 PF13401.6 KFR06911.1 - 0.09 13.0 1.1 24 5.2 0.1 3.6 4 0 0 4 4 4 0 AAA domain NBP1 PF08537.10 KFR06911.1 - 2.6 7.4 9.7 1.3 8.4 0.7 3.0 3 0 0 3 3 3 0 Fungal Nap binding protein NBP1 Sod_Cu PF00080.20 KFR06912.1 - 9.3e-45 152.3 5.3 1.1e-44 152.1 5.3 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CTD_bind PF04818.13 KFR06913.1 - 1.8e-17 63.9 0.0 6.1e-17 62.2 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 KFR06913.1 - 4.8e-09 35.9 0.0 1.1e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFR06913.1 - 0.026 14.4 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Npa1 PF11707.8 KFR06914.1 - 1.3e-89 300.9 9.8 1.2e-88 297.8 0.2 4.0 4 0 0 4 4 4 2 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KFR06914.1 - 3.2e-60 203.2 0.7 3.2e-60 203.2 0.7 4.9 5 1 0 5 5 5 1 Nucleolar pre-ribosomal-associated protein 1 FAM176 PF14851.6 KFR06915.1 - 3.7e-55 185.6 0.3 5.3e-55 185.1 0.3 1.2 1 0 0 1 1 1 1 FAM176 family Gal_Lectin PF02140.18 KFR06915.1 - 7.1e-39 132.1 7.9 1.9e-19 69.8 0.6 2.5 2 0 0 2 2 2 2 Galactose binding lectin domain DUF4210 PF13915.6 KFR06915.1 - 0.035 14.7 0.6 0.087 13.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4210) VIT1 PF01988.19 KFR06915.1 - 0.08 12.8 0.3 0.18 11.7 0.3 1.5 1 0 0 1 1 1 0 VIT family Pes-10 PF07149.11 KFR06915.1 - 2.3 7.2 7.5 3.3 6.7 7.5 1.1 1 0 0 1 1 1 0 Pes-10 DUF2870 PF11069.8 KFR06916.1 - 1e-39 134.8 2.6 1e-39 134.8 2.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2870) Syja_N PF02383.18 KFR06917.1 - 1.1e-69 235.3 0.2 1.6e-69 234.7 0.2 1.3 1 0 0 1 1 1 1 SacI homology domain DUF1866 PF08952.11 KFR06917.1 - 1.9e-57 193.2 0.2 1.5e-55 187.1 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1866) Exo_endo_phos PF03372.23 KFR06917.1 - 6e-16 58.7 0.1 1.2e-15 57.7 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family GCFC PF07842.12 KFR06918.1 - 8.8e-34 117.4 0.6 8.8e-34 117.4 0.6 1.9 2 1 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein BLOC1_2 PF10046.9 KFR06918.1 - 0.13 12.6 3.3 1.7 9.0 1.1 3.3 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4571 PF15137.6 KFR06919.1 - 3.1e-106 353.9 6.4 3.5e-106 353.7 6.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4571) ArlS_N PF18719.1 KFR06919.1 - 0.023 14.9 0.0 0.04 14.1 0.0 1.3 1 0 0 1 1 1 0 ArlS sensor domain Interfer-bind PF09294.10 KFR06920.1 - 4e-20 72.1 0.6 4.9e-20 71.8 0.6 1.1 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III Interfer-bind PF09294.10 KFR06921.1 - 2.2e-28 98.6 0.2 3.8e-28 97.8 0.0 1.5 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.21 KFR06921.1 - 7.4e-05 23.0 0.2 0.00019 21.7 0.2 1.6 2 0 0 2 2 2 1 Fibronectin type III domain Interfer-bind PF09294.10 KFR06922.1 - 7.4e-45 151.5 2.0 2.6e-21 75.9 0.0 3.1 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.17 KFR06922.1 - 1e-27 96.1 17.3 3.3e-14 52.6 0.8 3.6 3 1 1 4 4 4 2 Tissue factor fn3 PF00041.21 KFR06922.1 - 5.7e-08 33.0 12.6 0.00012 22.3 0.1 4.6 4 2 0 4 4 4 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFR06922.1 - 0.0053 17.3 5.9 1 9.9 0.0 3.6 4 0 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 KFR06922.1 - 0.015 15.7 0.1 1.5 9.3 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2369) Tissue_fac PF01108.17 KFR06923.1 - 1.9e-21 75.9 0.1 3.5e-21 75.1 0.1 1.4 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.10 KFR06923.1 - 1.4e-16 60.6 0.0 2.4e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III DUF4793 PF16041.5 KFR06923.1 - 0.06 13.5 0.0 0.099 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4793) UPF0220 PF05255.11 KFR06924.1 - 6.3e-51 172.2 4.6 7e-51 172.1 4.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF1218 PF06749.12 KFR06924.1 - 6.3 7.4 7.8 1.2 9.7 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) DUF1992 PF09350.10 KFR06925.1 - 7.9e-23 80.4 0.1 1.8e-22 79.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) DnaJ PF00226.31 KFR06925.1 - 6.3e-15 55.0 0.3 2.2e-14 53.3 0.1 2.1 1 1 1 2 2 2 1 DnaJ domain DUF3597 PF12200.8 KFR06925.1 - 0.016 15.8 0.2 0.03 14.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) GARS_A PF01071.19 KFR06926.1 - 6.6e-91 303.4 0.0 1.2e-90 302.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Formyl_trans_N PF00551.19 KFR06926.1 - 6.1e-67 224.9 0.1 1.4e-66 223.7 0.1 1.6 1 0 0 1 1 1 1 Formyl transferase AIRS_C PF02769.22 KFR06926.1 - 7.9e-40 136.5 0.1 6.9e-39 133.5 0.0 2.5 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 KFR06926.1 - 2e-37 127.9 0.4 1.5e-35 121.8 0.1 3.2 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 KFR06926.1 - 5.8e-29 100.2 1.1 3e-28 97.9 0.3 2.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KFR06926.1 - 2.8e-17 63.1 0.5 1.4e-16 60.9 0.5 2.3 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_3 PF02655.14 KFR06926.1 - 0.00061 19.9 0.0 0.0015 18.6 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 KFR06926.1 - 0.00074 19.1 0.0 0.002 17.8 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KFR06926.1 - 0.0025 17.4 0.0 0.0079 15.7 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 KFR06926.1 - 0.0035 17.0 0.1 0.01 15.4 0.1 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.10 KFR06926.1 - 0.042 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KFR06926.1 - 0.048 13.2 0.0 0.094 12.2 0.0 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus G-patch PF01585.23 KFR06927.1 - 2.5e-17 62.5 3.0 5.6e-17 61.4 3.0 1.6 1 0 0 1 1 1 1 G-patch domain dsrm PF00035.26 KFR06927.1 - 1.8e-14 54.2 0.0 5.5e-14 52.6 0.0 1.9 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KFR06927.1 - 3.5e-12 46.4 0.0 1.2e-11 44.7 0.0 2.0 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 G-patch_2 PF12656.7 KFR06927.1 - 2.7e-07 30.6 1.0 9.1e-07 28.9 1.0 1.9 1 0 0 1 1 1 1 G-patch domain RSRP PF17069.5 KFR06927.1 - 0.00025 20.7 0.7 0.00051 19.7 0.7 1.4 1 0 0 1 1 1 1 Arginine/Serine-Rich protein 1 ADH_zinc_N PF00107.26 KFR06929.1 - 3.8e-07 30.2 0.0 6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFR06929.1 - 0.054 14.6 0.0 0.17 12.9 0.0 1.9 2 1 0 2 2 2 0 Zinc-binding dehydrogenase PH_13 PF16652.5 KFR06931.1 - 7.9e-74 246.7 0.1 7.9e-74 246.7 0.1 4.0 3 1 1 4 4 2 1 Pleckstrin homology domain SH3_9 PF14604.6 KFR06931.1 - 1.3e-68 226.6 6.7 2.8e-16 59.1 0.1 5.4 5 0 0 5 5 5 5 Variant SH3 domain SH3_1 PF00018.28 KFR06931.1 - 1.1e-63 210.6 14.1 1.1e-16 60.1 0.3 5.5 5 0 0 5 5 5 5 SH3 domain SH3_2 PF07653.17 KFR06931.1 - 3e-57 190.1 1.5 4.8e-14 51.8 0.0 5.6 5 0 0 5 5 5 5 Variant SH3 domain INTAP PF16617.5 KFR06931.1 - 8.9e-55 184.0 12.9 8.9e-55 184.0 12.9 2.2 2 0 0 2 2 2 1 Intersectin and clathrin adaptor AP2 binding region RhoGEF PF00621.20 KFR06931.1 - 5.7e-46 157.0 2.0 5.7e-46 157.0 2.0 3.2 3 1 0 3 3 1 1 RhoGEF domain EF-hand_4 PF12763.7 KFR06931.1 - 6.7e-31 106.3 0.0 9.7e-15 54.4 0.0 3.1 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand C2 PF00168.30 KFR06931.1 - 2.4e-21 76.0 0.0 6.4e-21 74.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_1 PF00036.32 KFR06931.1 - 8e-09 34.4 0.0 0.0029 17.0 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFR06931.1 - 6.4e-07 28.8 0.2 0.39 10.8 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 KFR06931.1 - 4e-06 27.2 0.0 0.0059 17.0 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain pair PH PF00169.29 KFR06931.1 - 0.00079 19.9 0.0 0.0024 18.3 0.0 1.9 1 0 0 1 1 1 1 PH domain EF-hand_5 PF13202.6 KFR06931.1 - 0.0035 16.8 0.2 0.63 9.6 0.0 2.9 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KFR06931.1 - 0.065 13.1 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair GSH_synthase PF03199.15 KFR06931.1 - 0.066 13.7 1.7 0.34 11.4 0.2 3.1 2 1 0 2 2 2 0 Eukaryotic glutathione synthase OSCP PF00213.18 KFR06932.1 - 5.4e-47 160.1 0.4 6e-47 160.0 0.4 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF2630 PF10944.8 KFR06932.1 - 0.027 14.9 0.0 0.059 13.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) DNA_primase_lrg PF04104.14 KFR06932.1 - 0.083 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit SSF PF00474.17 KFR06933.1 - 1.3e-154 515.0 23.1 1.8e-154 514.6 23.1 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Ribosomal_S6 PF01250.17 KFR06934.1 - 6.3e-15 55.2 0.0 7.5e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 ISK_Channel PF02060.15 KFR06935.1 - 4.1e-16 58.8 0.1 5e-16 58.5 0.1 1.1 1 0 0 1 1 1 1 Slow voltage-gated potassium channel Viral_Beta_CD PF04530.12 KFR06935.1 - 0.11 12.8 0.1 0.14 12.5 0.1 1.1 1 0 0 1 1 1 0 Viral Beta C/D like family HsdM_N PF12161.8 KFR06935.1 - 0.13 12.9 0.3 0.24 12.0 0.1 1.5 2 0 0 2 2 2 0 HsdM N-terminal domain FAM165 PF14981.6 KFR06936.1 - 2.1e-31 107.5 3.9 2.2e-31 107.4 3.9 1.0 1 0 0 1 1 1 1 FAM165 family MadM PF03818.13 KFR06936.1 - 0.007 16.2 0.0 0.0081 16.0 0.0 1.1 1 0 0 1 1 1 1 Malonate/sodium symporter MadM subunit ISK_Channel PF02060.15 KFR06938.1 - 5.9e-58 193.9 0.1 6.6e-58 193.7 0.1 1.0 1 0 0 1 1 1 1 Slow voltage-gated potassium channel Calcipressin PF04847.12 KFR06939.1 - 1.6e-59 200.8 0.6 1.8e-59 200.6 0.6 1.0 1 0 0 1 1 1 1 Calcipressin GST_C_2 PF13410.6 KFR06940.1 - 1.4e-07 31.4 0.0 2.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFR06940.1 - 2.9e-05 24.3 0.0 6.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFR06940.1 - 6.1e-05 23.4 0.0 0.00012 22.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFR06940.1 - 0.0011 19.2 0.3 0.0056 16.9 0.1 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain EST1_DNA_bind PF10373.9 KFR06940.1 - 0.025 14.1 0.1 0.034 13.6 0.1 1.2 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain GST_C_3 PF14497.6 KFR06940.1 - 0.034 14.3 0.2 0.099 12.8 0.1 1.9 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Runt PF00853.19 KFR06941.1 - 2.2e-53 179.2 0.3 3.2e-53 178.7 0.3 1.2 1 0 0 1 1 1 1 Runt domain RunxI PF08504.11 KFR06941.1 - 9.7e-43 144.9 4.7 2.1e-42 143.8 4.7 1.6 1 0 0 1 1 1 1 Runx inhibition domain DUF3037 PF11236.8 KFR06941.1 - 0.045 14.2 0.0 0.072 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) SET PF00856.28 KFR06942.1 - 1e-10 42.3 0.0 1.8e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KFR06942.1 - 1.1e-09 39.1 1.0 2e-09 38.2 1.0 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Dna2 PF08696.11 KFR06942.1 - 0.15 11.9 0.5 0.3 10.9 0.3 1.6 2 0 0 2 2 2 0 DNA replication factor Dna2 adh_short PF00106.25 KFR06943.1 - 1.3e-32 112.9 0.0 1.7e-25 89.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFR06943.1 - 3.2e-24 85.8 0.0 6.6e-17 61.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFR06943.1 - 7.7e-06 25.9 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KFR06943.1 - 0.0011 18.2 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein HATPase_c PF02518.26 KFR06943.1 - 0.028 14.9 0.0 0.38 11.3 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Dopey_N PF04118.14 KFR06944.1 - 1.1e-97 326.8 1.7 3.3e-97 325.3 1.7 1.9 1 0 0 1 1 1 1 Dopey, N-terminal Lin-8 PF03353.15 KFR06944.1 - 0.057 13.0 8.3 0.15 11.6 8.3 1.7 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Phage_holin_4_1 PF05105.12 KFR06944.1 - 0.11 12.7 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Bacteriophage holin family CAF-1_p60_C PF15512.6 KFR06945.1 - 5.1e-65 219.3 26.7 6.9e-65 218.9 26.7 1.2 1 0 0 1 1 1 1 Chromatin assembly factor complex 1 subunit p60, C-terminal WD40 PF00400.32 KFR06945.1 - 1.5e-23 82.6 12.9 1.4e-06 28.9 0.5 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR06945.1 - 2.5e-14 53.3 0.2 0.00046 20.4 0.5 5.4 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFR06945.1 - 1.4e-05 25.0 0.7 0.0016 18.3 0.1 3.5 3 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 KFR06945.1 - 1.5e-05 24.3 0.1 0.0065 15.6 0.0 2.7 1 1 2 3 3 3 2 Coatomer WD associated region IKI3 PF04762.12 KFR06945.1 - 0.001 17.2 0.2 0.077 11.0 0.0 2.2 2 0 0 2 2 2 2 IKI3 family Ge1_WD40 PF16529.5 KFR06945.1 - 0.0026 16.8 0.2 0.33 9.9 0.0 3.1 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFR06945.1 - 0.05 12.2 0.5 1.4 7.5 0.0 2.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PD40 PF07676.12 KFR06945.1 - 2 8.5 7.1 7.7 6.6 1.2 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PMP22_Claudin PF00822.20 KFR06946.1 - 8.8e-33 113.5 11.4 1.1e-32 113.2 11.4 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFR06946.1 - 1.2e-08 35.0 14.9 2.5e-07 30.7 14.9 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.11 KFR06946.1 - 0.12 12.2 12.1 0.17 11.7 11.2 1.9 1 1 1 2 2 2 0 Amastin surface glycoprotein DUF872 PF05915.12 KFR06946.1 - 1 9.6 3.1 1.7 8.8 0.9 2.4 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) YtpI PF14007.6 KFR06946.1 - 1.9 8.6 5.6 0.69 10.1 0.7 2.5 2 1 1 3 3 3 0 YtpI-like protein DUF4064 PF13273.6 KFR06946.1 - 2.6 8.4 10.5 3.3e+02 1.6 11.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) BPL_LplA_LipB PF03099.19 KFR06948.1 - 4e-24 85.0 0.0 8.6e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_N PF09825.9 KFR06948.1 - 3.1e-15 56.1 1.0 7.5e-08 31.9 0.1 2.5 2 1 1 3 3 3 2 Biotin-protein ligase, N terminal BPL_C PF02237.17 KFR06948.1 - 3e-09 36.6 0.0 6.7e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain ABC_transp_aux PF09822.9 KFR06948.1 - 0.00021 20.9 0.1 0.00044 19.8 0.1 1.6 1 1 0 1 1 1 1 ABC-type uncharacterized transport system Ripply PF14998.6 KFR06949.1 - 4.5e-23 81.7 0.0 5.1e-23 81.5 0.0 1.0 1 0 0 1 1 1 1 Transcription Regulator PIG-P PF08510.12 KFR06950.1 - 5.4e-39 132.9 1.8 6e-39 132.7 1.8 1.0 1 0 0 1 1 1 1 PIG-P Phage_holin_3_6 PF07332.11 KFR06950.1 - 0.014 15.4 1.2 0.019 15.0 1.2 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III AgrB PF04647.15 KFR06950.1 - 0.29 10.4 2.8 7 5.9 0.8 2.0 1 1 1 2 2 2 0 Accessory gene regulator B DPM2 PF07297.12 KFR06950.1 - 0.71 10.2 11.1 2.3 8.6 11.1 1.8 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) TPR_1 PF00515.28 KFR06951.1 - 2.7e-11 42.8 11.8 0.00046 19.9 0.0 5.1 5 0 0 5 5 4 3 Tetratricopeptide repeat zf-RING_2 PF13639.6 KFR06951.1 - 4.1e-10 39.8 14.3 4.1e-10 39.8 14.3 3.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFR06951.1 - 8.4e-08 31.9 12.7 8.4e-08 31.9 12.7 3.0 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFR06951.1 - 5e-07 29.9 11.1 5e-07 29.9 11.1 3.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain TPR_11 PF13414.6 KFR06951.1 - 2.7e-06 26.9 3.4 0.00012 21.7 0.0 3.6 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.17 KFR06951.1 - 6.1e-06 26.0 15.9 0.074 13.2 0.0 5.7 6 0 0 6 6 5 3 Tetratricopeptide repeat zf-C3HC4 PF00097.25 KFR06951.1 - 6.4e-06 26.0 13.3 6.4e-06 26.0 13.3 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) TPR_12 PF13424.6 KFR06951.1 - 0.00016 21.9 8.9 0.02 15.1 0.0 4.2 4 1 0 4 4 3 1 Tetratricopeptide repeat zf-C3HC4_3 PF13920.6 KFR06951.1 - 0.00054 19.8 9.9 0.00054 19.8 9.9 3.2 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) TPR_16 PF13432.6 KFR06951.1 - 0.0014 19.2 0.2 0.66 10.7 0.0 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat zf-ANAPC11 PF12861.7 KFR06951.1 - 0.0019 18.2 4.9 0.0019 18.2 4.9 2.7 2 1 1 3 3 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_17 PF13431.6 KFR06951.1 - 0.003 17.8 0.7 0.046 14.1 0.2 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-RING_5 PF14634.6 KFR06951.1 - 0.0042 17.0 11.7 0.0042 17.0 11.7 3.1 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFR06951.1 - 0.0063 16.5 12.4 0.026 14.6 12.4 2.2 1 0 0 1 1 1 1 RING-type zinc-finger TPR_8 PF13181.6 KFR06951.1 - 0.018 15.2 4.7 0.58 10.5 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFR06951.1 - 0.024 15.4 0.5 7.7 7.6 0.0 3.9 4 0 0 4 4 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFR06951.1 - 0.038 14.2 2.9 0.19 11.9 0.7 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KFR06951.1 - 0.05 14.1 0.7 5.7 7.5 0.0 3.6 2 2 1 3 3 3 0 Tetratricopeptide repeat zf-RING_11 PF17123.5 KFR06951.1 - 0.056 13.2 10.9 0.22 11.3 10.9 2.1 1 0 0 1 1 1 0 RING-like zinc finger PAM2 PF07145.15 KFR06951.1 - 0.13 12.0 0.3 0.35 10.7 0.3 1.7 1 0 0 1 1 1 0 Ataxin-2 C-terminal region zf-Nse PF11789.8 KFR06951.1 - 0.5 10.2 5.6 1.4 8.8 5.6 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit YjbH PF06082.11 KFR06951.1 - 0.53 9.0 7.0 0.98 8.2 7.0 1.3 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Prok-RING_4 PF14447.6 KFR06951.1 - 1.5 8.8 10.9 8.1 6.4 10.8 2.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 KFR06951.1 - 5.3 7.3 15.9 1.2 9.4 7.4 3.2 2 0 0 2 2 2 0 FANCL C-terminal domain Vps26 PF03643.15 KFR06952.1 - 5.1e-68 229.1 0.2 5.9e-68 228.8 0.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KFR06952.1 - 0.00026 21.1 0.3 0.0024 17.9 0.1 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Pkinase PF00069.25 KFR06953.1 - 7.3e-50 169.8 0.0 1.1e-49 169.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR06953.1 - 5.1e-22 78.4 0.0 9.1e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Filament_head PF04732.14 KFR06953.1 - 0.41 11.5 26.2 0.44 11.4 8.0 2.7 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region IRK_C PF17655.1 KFR06954.1 - 1.3e-72 243.0 0.0 1.9e-72 242.5 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFR06954.1 - 4.1e-58 195.2 3.5 6.2e-58 194.6 3.5 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 KFR06954.1 - 0.19 11.7 10.9 0.76 9.8 10.9 2.0 1 1 0 1 1 1 0 Ion channel IRK_C PF17655.1 KFR06955.1 - 1.5e-64 216.8 0.1 2.2e-64 216.3 0.1 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFR06955.1 - 1.5e-57 193.4 1.6 2.4e-57 192.7 1.6 1.4 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 KFR06955.1 - 0.014 15.4 4.5 0.032 14.2 4.5 1.7 1 1 0 1 1 1 0 Ion channel DUF2182 PF09948.9 KFR06955.1 - 0.11 12.4 0.2 0.18 11.7 0.2 1.3 1 0 0 1 1 1 0 Predicted metal-binding integral membrane protein (DUF2182) Ets PF00178.22 KFR06956.1 - 2e-36 124.3 0.4 3.8e-36 123.4 0.4 1.5 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 KFR06956.1 - 2.2e-26 91.7 0.0 4.3e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.17 KFR06956.1 - 0.0076 16.3 0.1 0.081 13.0 0.1 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_3 PF18016.1 KFR06956.1 - 0.019 14.8 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFR06956.1 - 0.082 13.4 0.2 0.22 12.0 0.2 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Ets PF00178.22 KFR06958.1 - 1.2e-36 125.0 1.1 1.2e-36 125.0 1.1 2.0 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.16 KFR06958.1 - 3.5e-34 116.6 1.0 7e-34 115.7 1.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PAC1 PF16094.5 KFR06959.1 - 6.9e-65 219.0 3.5 7.7e-65 218.9 3.5 1.0 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 EF-G-binding_N PF07299.11 KFR06959.1 - 0.043 14.3 0.1 0.074 13.6 0.1 1.4 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal Bromodomain PF00439.25 KFR06960.1 - 7.5e-38 128.5 0.1 1e-17 64.0 0.0 2.7 2 0 0 2 2 2 2 Bromodomain WD40 PF00400.32 KFR06960.1 - 3.1e-37 125.9 14.5 4.6e-06 27.3 0.6 8.7 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR06960.1 - 2.1e-07 31.1 0.1 0.38 11.1 0.1 5.2 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFR06960.1 - 0.057 13.3 0.0 2.4 8.0 0.0 2.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KFR06960.1 - 0.19 11.0 0.0 5.9 6.1 0.0 2.7 3 0 0 3 3 3 0 WD40-like domain HMG14_17 PF01101.18 KFR06961.1 - 6.3e-22 78.4 19.9 6.8e-22 78.2 19.9 1.0 1 0 0 1 1 1 1 HMG14 and HMG17 CHD5 PF04420.14 KFR06962.1 - 2.7e-37 128.1 0.6 3e-37 127.9 0.6 1.0 1 0 0 1 1 1 1 CHD5-like protein DUF2203 PF09969.9 KFR06962.1 - 0.0021 18.8 1.5 0.086 13.6 0.6 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2203) DUF1043 PF06295.12 KFR06962.1 - 0.0031 17.5 1.4 0.0039 17.2 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) Lectin_N PF03954.14 KFR06962.1 - 0.089 12.5 0.8 0.14 11.9 0.8 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain MCU PF04678.13 KFR06962.1 - 0.13 12.4 5.6 0.89 9.6 5.6 1.9 1 1 0 1 1 1 0 Mitochondrial calcium uniporter DUF1640 PF07798.11 KFR06962.1 - 0.25 11.4 7.2 0.5 10.4 7.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) MatP_C PF17414.2 KFR06962.1 - 0.7 10.1 4.1 1.8 8.8 1.0 2.2 1 1 1 2 2 2 0 MatP C-terminal ribbon-helix-helix domain SH3BGR PF04908.15 KFR06963.1 - 1.8e-40 137.1 0.3 2e-40 136.9 0.3 1.0 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 KFR06963.1 - 0.00032 20.8 0.0 0.00045 20.4 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin I-set PF07679.16 KFR06964.1 - 2.9e-16 59.3 0.1 9.8e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR06964.1 - 1.1e-15 58.0 1.8 2e-07 31.5 0.1 2.6 3 0 0 3 3 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFR06964.1 - 5.3e-11 42.7 0.7 1.3e-05 25.5 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFR06964.1 - 2.1e-10 40.6 3.2 0.00023 21.2 0.2 2.8 2 2 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFR06964.1 - 1.8e-09 37.5 0.6 3.4e-05 23.8 0.1 2.4 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFR06964.1 - 2.2e-05 24.7 0.3 0.00058 20.2 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin C1-set domain Shisa PF13908.6 KFR06964.1 - 0.00025 21.3 1.3 0.00047 20.5 1.3 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator V-set PF07686.17 KFR06964.1 - 0.00041 20.5 2.4 0.91 9.7 0.1 3.3 2 2 0 2 2 2 2 Immunoglobulin V-set domain TMEM154 PF15102.6 KFR06964.1 - 0.00063 19.7 0.7 0.00063 19.7 0.7 1.6 2 0 0 2 2 1 1 TMEM154 protein family TMEM52 PF14979.6 KFR06964.1 - 0.00068 19.6 0.2 0.0012 18.7 0.2 1.4 1 0 0 1 1 1 1 Transmembrane 52 Marek_A PF02124.15 KFR06964.1 - 0.0021 17.9 3.0 0.0037 17.1 3.0 1.5 1 1 0 1 1 1 1 Marek's disease glycoprotein A Protocadherin PF08374.11 KFR06964.1 - 0.0037 17.3 0.7 0.0062 16.5 0.7 1.3 1 0 0 1 1 1 1 Protocadherin Orthoreo_P10 PF07204.11 KFR06964.1 - 0.0042 17.0 0.1 0.008 16.1 0.1 1.5 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 DAG1 PF05454.11 KFR06964.1 - 0.019 14.3 0.2 0.023 14.1 0.2 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) TMEM51 PF15345.6 KFR06964.1 - 0.027 14.3 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 C2-set PF05790.15 KFR06964.1 - 0.033 14.4 1.3 3.9 7.7 0.0 2.8 3 1 0 3 3 2 0 Immunoglobulin C2-set domain DUF2207 PF09972.9 KFR06964.1 - 0.034 12.9 0.1 0.13 11.0 0.1 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) LRR19-TM PF15176.6 KFR06964.1 - 0.076 13.0 0.3 0.18 11.8 0.3 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain MLANA PF14991.6 KFR06964.1 - 0.082 13.2 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein melan-A Mid2 PF04478.12 KFR06964.1 - 0.082 12.7 5.7 0.11 12.3 4.6 1.8 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor Orf78 PF06024.12 KFR06964.1 - 0.16 12.3 0.5 0.3 11.4 0.5 1.5 1 0 0 1 1 1 0 Orf78 (ac78) TMIE PF16038.5 KFR06964.1 - 1.4 8.8 5.1 2.6 7.9 5.1 1.4 1 0 0 1 1 1 0 TMIE protein EphA2_TM PF14575.6 KFR06964.1 - 2 9.4 3.9 4.7 8.2 3.9 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain IQ PF00612.27 KFR06965.1 - 0.0093 15.7 0.5 0.013 15.2 0.5 1.2 1 0 0 1 1 1 1 IQ calmodulin-binding motif Ig_2 PF13895.6 KFR06966.1 - 2.5e-06 27.7 0.0 4.2e-05 23.8 0.0 2.2 2 1 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 KFR06966.1 - 6.4e-05 23.5 0.0 0.0024 18.4 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Asp PF00026.23 KFR06967.1 - 1e-38 133.5 0.1 1.9e-38 132.7 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KFR06967.1 - 5.5e-13 49.0 0.0 8e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 KFR06967.1 - 0.0053 17.0 0.0 0.021 15.1 0.0 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Dynamin_M PF01031.20 KFR06968.1 - 1.3e-79 267.4 10.1 2.2e-79 266.7 10.1 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KFR06968.1 - 3.1e-46 157.5 0.0 1e-45 155.9 0.0 1.9 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KFR06968.1 - 6.1e-17 61.6 0.3 4.1e-16 58.9 0.0 2.5 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KFR06968.1 - 0.0003 20.9 0.1 0.0024 17.9 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFR06968.1 - 0.0046 17.3 1.0 0.08 13.3 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 KFR06968.1 - 0.0077 16.1 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system CHDNT PF08073.12 KFR06968.1 - 0.03 14.3 0.0 0.19 11.7 0.0 2.4 2 0 0 2 2 2 0 CHDNT (NUC034) domain ABC_tran PF00005.27 KFR06968.1 - 0.044 14.3 0.2 0.29 11.6 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 KFR06968.1 - 0.065 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 KFR06968.1 - 0.16 11.6 0.0 0.16 11.6 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain P4Ha_N PF08336.11 KFR06968.1 - 6.1 6.9 9.2 0.79 9.7 0.4 3.1 3 1 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Trypsin PF00089.26 KFR06969.1 - 1.1e-70 237.9 1.1 1.5e-70 237.4 1.1 1.2 1 0 0 1 1 1 1 Trypsin SRCR_2 PF15494.6 KFR06969.1 - 3.3e-30 104.5 0.3 6.4e-30 103.6 0.3 1.5 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain DUF1986 PF09342.11 KFR06969.1 - 5.9e-10 39.5 0.1 1.7e-09 38.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Hepsin-SRCR PF09272.10 KFR06969.1 - 2.7e-09 37.5 0.1 5.8e-09 36.5 0.1 1.5 1 0 0 1 1 1 1 Hepsin, SRCR domain Ldl_recept_a PF00057.18 KFR06969.1 - 8.6e-06 25.9 7.5 2.9e-05 24.2 7.5 2.0 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A SRCR PF00530.18 KFR06969.1 - 2.4e-05 24.8 0.1 7.5e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Trypsin_2 PF13365.6 KFR06969.1 - 0.0002 22.3 0.0 0.00054 20.9 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF3357 PF11837.8 KFR06969.1 - 0.093 13.2 0.2 3.8 8.0 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) zf-C2H2 PF00096.26 KFR06970.1 - 3.2e-47 156.4 139.1 7.5e-06 26.1 1.1 17.8 18 0 0 18 18 17 16 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR06970.1 - 1.2e-43 144.0 128.4 0.00055 20.6 0.5 17.9 18 0 0 18 18 17 16 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFR06970.1 - 1.3e-30 104.4 111.2 1.4e-05 25.3 0.5 17.5 18 0 0 18 18 17 10 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFR06970.1 - 1e-20 73.4 96.1 0.0064 16.8 0.8 17.7 18 0 0 18 18 18 9 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFR06970.1 - 2.8e-16 59.3 102.0 0.012 16.0 0.2 16.7 17 0 0 17 17 17 11 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFR06970.1 - 1.2e-06 28.4 105.2 0.27 11.3 0.0 16.8 17 0 0 17 17 17 7 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFR06970.1 - 2.8e-05 23.9 46.7 0.021 14.7 0.2 10.8 11 0 0 11 11 11 4 zinc-finger of a C2HC-type SET PF00856.28 KFR06970.1 - 0.0021 18.5 0.1 0.012 16.0 0.0 2.4 3 0 0 3 3 3 1 SET domain zf-MYST PF17772.1 KFR06970.1 - 0.014 14.9 0.9 0.014 14.9 0.9 9.8 10 2 2 12 12 12 0 MYST family zinc finger domain zinc_ribbon_15 PF17032.5 KFR06970.1 - 0.048 14.4 66.9 2 9.2 0.8 9.3 6 2 2 9 9 9 0 zinc-ribbon family BolA PF01722.18 KFR06970.1 - 0.36 11.1 13.4 54 4.2 0.1 6.7 5 2 2 7 7 7 0 BolA-like protein SMP_C2CD2L PF18696.1 KFR06971.1 - 5.4e-45 152.9 2.1 5.4e-45 152.9 2.1 2.0 2 0 0 2 2 2 1 Synaptotagmin-like, mitochondrial and lipid-binding domain C2 PF00168.30 KFR06971.1 - 3.5e-09 36.9 0.5 1.9e-08 34.5 0.0 2.5 3 0 0 3 3 3 1 C2 domain CEP76-C2 PF15627.6 KFR06971.1 - 0.039 13.5 0.0 0.095 12.3 0.0 1.6 1 0 0 1 1 1 0 CEP76 C2 domain DOCK-C2 PF14429.6 KFR06971.1 - 0.073 12.9 0.4 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins BTB PF00651.31 KFR06972.1 - 6.6e-26 90.7 0.1 1.3e-25 89.8 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf_C2H2_6 PF18450.1 KFR06972.1 - 1.3e-18 66.3 5.8 1.3e-18 66.3 5.8 3.6 3 0 0 3 3 3 1 Zinc Finger domain zf-C2H2 PF00096.26 KFR06972.1 - 1.5e-15 56.7 69.8 0.00089 19.6 1.7 9.3 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR06972.1 - 8.7e-15 54.2 72.4 0.013 16.2 0.9 9.6 9 0 0 9 9 9 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFR06972.1 - 0.0063 16.9 4.7 0.0063 16.9 4.7 10.8 11 1 0 11 11 11 3 Zinc-finger double domain zf-met PF12874.7 KFR06972.1 - 0.014 15.8 39.2 0.042 14.2 2.4 7.7 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KFR06972.1 - 0.015 15.7 34.0 0.025 15.0 0.0 6.5 5 2 1 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger zf-MYST PF17772.1 KFR06972.1 - 0.53 9.9 0.0 0.53 9.9 0.0 6.6 7 2 2 9 9 9 0 MYST family zinc finger domain zf-C2H2_6 PF13912.6 KFR06972.1 - 1.9 8.6 52.7 0.51 10.4 0.5 8.3 9 0 0 9 9 9 0 C2H2-type zinc finger Desulfoferrod_N PF06397.12 KFR06972.1 - 2 8.1 7.8 46 3.8 0.1 4.5 4 0 0 4 4 4 0 Desulfoferrodoxin, N-terminal domain zf-C2H2_jaz PF12171.8 KFR06972.1 - 2.7 8.4 50.5 0.14 12.5 2.3 8.8 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding PknG_rubred PF16919.5 KFR06972.1 - 4 7.6 6.0 6.9 6.8 0.0 3.7 4 0 0 4 4 4 0 Protein kinase G rubredoxin domain Aldo_ket_red PF00248.21 KFR07027.1 - 4e-52 177.3 0.0 7.6e-52 176.3 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family Dev_Cell_Death PF10539.9 KFR07027.1 - 0.14 12.0 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 Development and cell death domain Aldo_ket_red PF00248.21 KFR07028.1 - 1.6e-50 172.0 0.0 2.5e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family UCH PF00443.29 KFR07029.1 - 1.3e-42 146.1 3.6 1.6e-42 145.8 3.6 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFR07029.1 - 6.2e-26 91.8 12.4 1.3e-25 90.7 12.4 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Tubulin PF00091.25 KFR07030.1 - 1.1e-66 224.8 0.0 1.6e-66 224.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFR07030.1 - 2.2e-51 173.3 0.0 3.6e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFR07030.1 - 0.0016 18.1 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Pex26 PF07163.12 KFR07031.1 - 1.4e-87 293.8 4.6 1.5e-87 293.7 4.6 1.0 1 0 0 1 1 1 1 Pex26 protein CH PF00307.31 KFR07032.1 - 1.5e-20 73.4 0.0 4.8e-20 71.8 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFR07032.1 - 6e-13 48.4 0.0 1.9e-12 46.9 0.0 1.9 1 0 0 1 1 1 1 CAMSAP CH domain LIM PF00412.22 KFR07032.1 - 8.8e-09 35.5 10.1 1.7e-08 34.6 10.1 1.5 1 0 0 1 1 1 1 LIM domain FAD_binding_3 PF01494.19 KFR07032.1 - 1.2e-05 24.8 0.0 2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KFR07032.1 - 4.4e-05 22.9 0.0 0.0001 21.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFR07032.1 - 0.00019 20.8 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFR07032.1 - 0.00068 18.4 0.0 0.0012 17.6 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KFR07032.1 - 0.0012 18.0 0.0 0.0023 17.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 KFR07032.1 - 0.0031 17.9 0.0 0.011 16.2 0.0 1.9 2 0 0 2 2 1 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KFR07032.1 - 0.0041 17.3 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFR07032.1 - 0.0052 17.3 0.0 0.02 15.4 0.0 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFR07032.1 - 0.0066 16.1 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFR07032.1 - 0.027 13.7 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 KFR07032.1 - 0.057 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KFR07032.1 - 0.092 11.8 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein BID PF06393.11 KFR07033.1 - 6.2e-71 237.9 0.9 6.9e-71 237.7 0.9 1.0 1 0 0 1 1 1 1 BH3 interacting domain (BID) Bcl-2 PF00452.19 KFR07033.1 - 0.00068 20.3 0.1 0.0011 19.6 0.1 1.4 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family Clathrin-link PF09268.10 KFR07033.1 - 0.0036 16.6 0.5 0.094 12.1 0.8 2.5 2 0 0 2 2 2 1 Clathrin, heavy-chain linker DUF3349 PF11829.8 KFR07033.1 - 0.011 16.4 0.5 0.035 14.9 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) CRM1_C PF08767.11 KFR07033.1 - 0.021 14.0 0.8 0.035 13.3 0.8 1.3 1 1 0 1 1 1 0 CRM1 C terminal TAFH PF07531.14 KFR07033.1 - 0.036 14.2 0.3 0.23 11.6 0.3 2.3 2 1 0 2 2 2 0 NHR1 homology to TAF Bcl-2 PF00452.19 KFR07035.1 - 9.3e-12 45.5 0.0 1.5e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family T3SS_needle_E PF08988.10 KFR07035.1 - 0.011 15.8 0.5 0.011 15.8 0.5 2.2 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle DUF4549 PF15082.6 KFR07035.1 - 0.05 13.4 2.0 0.14 12.0 2.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4549) DUF842 PF05811.13 KFR07035.1 - 0.086 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) vATP-synt_E PF01991.18 KFR07036.1 - 1.6e-75 252.9 12.2 1.8e-75 252.7 12.2 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4288 PF14119.6 KFR07036.1 - 0.021 15.2 3.2 0.03 14.7 2.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) ATP-synt_B PF00430.18 KFR07036.1 - 0.058 13.5 0.5 0.058 13.5 0.5 2.5 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Tn7_Tnp_TnsA_C PF08721.11 KFR07036.1 - 0.33 11.6 4.3 7.1 7.4 0.6 2.7 1 1 1 2 2 2 0 TnsA endonuclease C terminal NifW PF03206.14 KFR07036.1 - 0.34 11.5 4.4 0.28 11.7 2.4 1.8 1 1 1 2 2 2 0 Nitrogen fixation protein NifW OmpH PF03938.14 KFR07036.1 - 0.62 10.4 16.9 1 9.7 16.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) A_deaminase PF00962.22 KFR07037.1 - 8.5e-22 77.9 0.0 1.6e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 KFR07037.1 - 4.1e-17 62.3 0.0 1.2e-16 60.7 0.0 1.8 2 0 0 2 2 2 1 Adenosine/AMP deaminase N-terminal Hydrolase_like PF13242.6 KFR07038.1 - 2.8e-09 36.9 0.0 1e-08 35.1 0.0 2.0 2 1 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KFR07038.1 - 0.069 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase IL17R_fnIII_D1 PF16556.5 KFR07039.1 - 3e-60 202.3 0.6 5.9e-60 201.4 0.6 1.5 1 0 0 1 1 1 1 Interleukin-17 receptor, fibronectin-III-like domain 1 SEFIR PF08357.11 KFR07039.1 - 2.4e-43 148.0 0.0 4.4e-43 147.1 0.0 1.5 1 0 0 1 1 1 1 SEFIR domain IL17R_fnIII_D2 PF16578.5 KFR07039.1 - 6.6e-38 129.5 0.6 6.6e-38 129.5 0.6 2.1 2 0 0 2 2 2 1 Interleukin 17 receptor D DCP1 PF06058.13 KFR07040.1 - 3e-28 98.1 0.1 9.2e-28 96.5 0.0 1.9 2 0 0 2 2 2 1 Dcp1-like decapping family mRNA_decap_C PF16741.5 KFR07040.1 - 7.4e-20 70.0 1.1 1.5e-19 69.0 1.1 1.6 1 0 0 1 1 1 1 mRNA-decapping enzyme C-terminus VGCC_alpha2 PF08473.11 KFR07041.1 - 5.1e-38 131.0 0.1 1.7e-37 129.3 0.1 1.7 1 1 0 1 1 1 1 Neuronal voltage-dependent calcium channel alpha 2acd VWA_N PF08399.11 KFR07041.1 - 4.2e-37 127.4 0.1 7.5e-37 126.5 0.1 1.4 1 0 0 1 1 1 1 VWA N-terminal VWA_3 PF13768.6 KFR07041.1 - 4e-15 56.1 0.0 8.5e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain dCache_1 PF02743.18 KFR07041.1 - 1.6e-12 47.7 1.5 3.9e-10 39.9 0.0 3.4 2 1 1 3 3 3 1 Cache domain VWA PF00092.28 KFR07041.1 - 1.8e-12 47.9 0.1 2.9e-12 47.2 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFR07041.1 - 5.5e-11 43.1 0.1 1.1e-10 42.1 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KFR07041.1 - 0.081 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein CobT_C PF11775.8 KFR07041.1 - 0.19 11.4 0.0 0.38 10.4 0.0 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain LRR_8 PF13855.6 KFR07042.1 - 2.7e-24 84.7 26.3 2e-12 46.7 1.1 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFR07042.1 - 1.7e-11 44.2 17.7 0.0013 19.1 2.9 3.6 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRRNT PF01462.18 KFR07042.1 - 4.8e-09 35.7 3.3 4.8e-09 35.7 3.3 2.3 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.6 KFR07042.1 - 3.4e-08 33.5 0.0 5e-07 29.7 0.0 2.4 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFR07042.1 - 5.2e-05 22.8 4.1 0.00032 20.3 3.1 2.0 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFR07042.1 - 0.007 16.8 17.7 0.034 14.7 0.7 5.1 4 1 0 4 4 4 1 Leucine Rich Repeat Shisa PF13908.6 KFR07042.1 - 0.0072 16.6 0.2 0.012 15.9 0.2 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator LRR_6 PF13516.6 KFR07042.1 - 2.5 8.4 9.6 52 4.3 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich repeat HlyIII PF03006.20 KFR07043.1 - 2.8e-72 243.1 21.2 3.5e-72 242.8 21.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF3493 PF11998.8 KFR07043.1 - 0.29 11.3 1.0 1.5 9.0 1.0 2.2 1 1 0 1 1 1 0 Low psii accumulation1 / Rep27 wnt PF00110.19 KFR07044.1 - 6.7e-105 351.1 21.0 2.3e-104 349.3 21.0 1.7 1 1 0 1 1 1 1 wnt family Cast PF10174.9 KFR07045.1 - 0 1089.8 144.9 0 1089.6 144.9 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Spc7 PF08317.11 KFR07045.1 - 0.0015 17.5 16.0 0.0015 17.5 16.0 7.5 1 1 7 8 8 8 4 Spc7 kinetochore protein PKcGMP_CC PF16808.5 KFR07045.1 - 0.0022 17.8 0.6 0.0022 17.8 0.6 12.5 14 2 1 15 15 15 3 Coiled-coil N-terminus of cGMP-dependent protein kinase AAA_13 PF13166.6 KFR07045.1 - 0.0024 16.6 25.1 0.0024 16.6 25.1 5.3 1 1 2 4 4 4 1 AAA domain Troponin PF00992.20 KFR07045.1 - 0.014 15.7 21.6 0.014 15.7 21.6 8.2 2 2 5 8 8 8 0 Troponin DUF5617 PF18493.1 KFR07045.1 - 0.79 9.9 4.9 0.59 10.3 0.3 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF5617) Phage_tail_NK PF16532.5 KFR07045.1 - 4.9 6.8 7.7 8.3 6.0 0.5 3.5 3 0 0 3 3 3 0 Sf6-type phage tail needle knob or tip of some Caudovirales Rad52_Rad22 PF04098.15 KFR07046.1 - 1.1e-48 165.0 0.8 1.4e-48 164.7 0.0 1.6 2 0 0 2 2 2 1 Rad52/22 family double-strand break repair protein WW_FCH_linker PF16623.5 KFR07046.1 - 8.6 7.2 11.1 0.43 11.4 4.7 2.1 2 0 0 2 2 2 0 Unstructured linker region between on GAS7 protein Pkinase PF00069.25 KFR07047.1 - 2.8e-53 181.0 0.0 4.1e-53 180.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR07047.1 - 4.5e-41 140.8 0.0 6.8e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 KFR07047.1 - 2.2e-30 104.7 3.9 2.3e-26 91.8 0.3 2.4 2 0 0 2 2 2 2 Oxidative-stress-responsive kinase 1 C-terminal domain Ninjurin PF04923.12 KFR07048.1 - 2.7e-35 120.4 10.6 3e-35 120.2 10.6 1.0 1 0 0 1 1 1 1 Ninjurin DUF1418 PF07214.12 KFR07048.1 - 0.14 12.0 3.2 0.24 11.3 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) DHHC PF01529.20 KFR07048.1 - 4.7 7.3 7.9 0.51 10.4 1.5 1.8 1 1 1 2 2 2 0 DHHC palmitoyltransferase CHGN PF05679.16 KFR07049.1 - 5.5e-25 88.2 0.0 2e-24 86.3 0.0 1.8 1 1 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 KFR07049.1 - 2.5e-12 46.3 0.7 5.4e-12 45.2 0.7 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase PA14 PF07691.12 KFR07049.1 - 3.8e-07 30.0 0.0 7.6e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 PA14 domain GLEYA PF10528.9 KFR07049.1 - 0.083 13.3 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 GLEYA domain Ribosomal_60s PF00428.19 KFR07049.1 - 6.4 7.4 7.9 26 5.5 7.9 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pox_A_type_inc PF04508.12 KFR07050.1 - 1.6 8.7 0.0 1.6 8.7 0.0 4.6 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Atg14 PF10186.9 KFR07050.1 - 2.5 7.1 48.4 0.58 9.2 13.4 3.4 1 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 MscS_porin PF12795.7 KFR07050.1 - 4.9 6.6 40.4 0.65 9.5 2.5 4.0 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain TBK1_ULD PF18396.1 KFR07050.1 - 8.3 6.4 7.4 4 7.4 0.8 3.1 2 1 1 3 3 3 0 TANK binding kinase 1 ubiquitin-like domain PLU-1 PF08429.11 KFR07051.1 - 1e-100 337.3 11.1 1e-100 337.3 11.1 4.7 4 1 0 4 4 4 2 PLU-1-like protein JmjC PF02373.22 KFR07051.1 - 2.4e-46 156.9 1.4 7.3e-46 155.3 1.4 2.0 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 KFR07051.1 - 2.1e-25 88.3 46.9 2.3e-12 46.6 3.3 3.9 4 0 0 4 4 4 3 PHD-finger ARID PF01388.21 KFR07051.1 - 2.5e-19 69.7 0.0 8.6e-19 68.0 0.0 2.0 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.16 KFR07051.1 - 1.7e-14 53.9 12.4 1.7e-14 53.9 12.4 3.4 3 0 0 3 3 3 1 C5HC2 zinc finger FRG1 PF06229.12 KFR07051.1 - 0.028 14.2 11.3 5.8 6.6 0.0 2.8 2 0 0 2 2 2 0 FRG1-like domain PHD_2 PF13831.6 KFR07051.1 - 0.44 10.2 20.0 0.7 9.5 0.5 3.8 3 1 0 3 3 3 0 PHD-finger TadF PF16964.5 KFR07051.1 - 2.8 7.6 6.8 5.5 6.7 3.0 2.6 2 0 0 2 2 2 0 Putative tight adherence pilin protein F SNF PF00209.18 KFR07052.1 - 6.5e-246 817.0 36.6 7.5e-246 816.8 36.6 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 KFR07053.1 - 1.2e-243 809.6 36.8 1.4e-243 809.4 36.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 KFR07054.1 - 6.5e-229 760.9 40.5 7.5e-229 760.7 40.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Sec7 PF01369.20 KFR07055.1 - 4.8e-62 208.9 0.0 1.2e-61 207.6 0.0 1.7 1 0 0 1 1 1 1 Sec7 domain IQ_SEC7_PH PF16453.5 KFR07055.1 - 1.8e-61 206.1 2.5 2.7e-61 205.6 0.8 2.1 2 0 0 2 2 2 1 PH domain AAA_35 PF14516.6 KFR07055.1 - 0.016 14.0 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain IQ PF00612.27 KFR07055.1 - 0.47 10.4 2.7 0.57 10.1 0.3 2.4 2 0 0 2 2 2 0 IQ calmodulin-binding motif zf-H2C2_2 PF13465.6 KFR07056.1 - 2.5e-65 214.2 56.7 6.9e-11 42.1 0.5 8.7 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFR07056.1 - 5.3e-60 196.7 57.2 6.5e-08 32.6 1.9 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR07056.1 - 3.1e-38 127.1 53.3 3.6e-05 24.2 0.9 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFR07056.1 - 4.8e-25 87.0 48.9 3e-05 23.9 0.9 8.4 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFR07056.1 - 2.1e-21 75.7 26.7 0.008 16.4 0.1 8.2 8 0 0 8 8 8 6 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFR07056.1 - 1.2e-13 50.4 32.6 0.028 14.0 0.4 8.2 7 1 1 8 8 8 7 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFR07056.1 - 5.9e-13 48.7 38.1 0.0011 19.1 2.5 5.6 3 2 3 6 6 6 5 Zinc ribbon domain zf-met PF12874.7 KFR07056.1 - 1e-12 48.0 47.3 0.16 12.4 0.1 8.2 8 0 0 8 8 8 7 Zinc-finger of C2H2 type XPA_N PF01286.18 KFR07056.1 - 4.3e-09 36.3 35.5 0.072 13.1 0.5 8.1 8 0 0 8 8 8 3 XPA protein N-terminal zf-C2H2_11 PF16622.5 KFR07056.1 - 1.4e-08 34.4 38.8 0.19 11.5 0.6 8.1 8 0 0 8 8 8 6 zinc-finger C2H2-type Prok-RING_1 PF14446.6 KFR07056.1 - 2.1e-07 30.8 18.6 8.5 6.4 0.1 8.0 7 1 1 8 8 8 0 Prokaryotic RING finger family 1 CpXC PF14353.6 KFR07056.1 - 3.2e-07 30.4 25.3 0.61 10.1 0.1 7.8 4 2 0 5 5 5 1 CpXC protein zinc_ribbon_15 PF17032.5 KFR07056.1 - 3.5e-07 30.9 28.5 0.057 14.2 4.5 4.1 1 1 3 4 4 4 4 zinc-ribbon family zf-Di19 PF05605.12 KFR07056.1 - 1.9e-06 28.1 30.5 0.011 16.0 1.5 4.9 2 2 2 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding LIM PF00412.22 KFR07056.1 - 3.9e-06 27.0 28.7 0.11 12.8 0.8 5.8 2 2 4 6 6 6 3 LIM domain zf-LYAR PF08790.11 KFR07056.1 - 7.5e-06 25.7 30.4 0.65 9.9 0.4 8.0 8 0 0 8 8 8 2 LYAR-type C2HC zinc finger Zn_Tnp_IS1595 PF12760.7 KFR07056.1 - 8e-05 22.5 43.3 0.15 12.1 2.8 6.2 4 2 2 6 6 6 3 Transposase zinc-ribbon domain C1_4 PF07975.12 KFR07056.1 - 9.6e-05 22.5 32.9 0.18 12.0 2.2 6.1 1 1 6 7 7 7 3 TFIIH C1-like domain YhfH PF14149.6 KFR07056.1 - 0.00037 20.4 29.1 3.4 7.7 0.2 7.3 8 0 0 8 8 7 0 YhfH-like protein ADK_lid PF05191.14 KFR07056.1 - 0.00039 20.3 24.5 0.33 11.0 0.4 5.5 4 1 1 5 5 5 4 Adenylate kinase, active site lid DNA_RNApol_7kD PF03604.13 KFR07056.1 - 0.00041 20.0 24.1 5.6 6.7 0.2 7.9 8 0 0 8 8 8 0 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 KFR07056.1 - 0.00043 20.3 27.8 0.36 10.9 1.5 4.9 1 1 5 6 6 6 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FYDLN_acid PF09538.10 KFR07056.1 - 0.0011 19.6 23.8 17 6.1 2.9 7.2 1 1 5 6 6 6 0 Protein of unknown function (FYDLN_acid) zf-AN1 PF01428.16 KFR07056.1 - 0.0016 18.6 42.2 6.3 7.1 0.6 8.2 6 2 2 8 8 8 0 AN1-like Zinc finger zf-trcl PF13451.6 KFR07056.1 - 0.0017 18.2 29.1 7.9 6.5 0.1 7.9 8 0 0 8 8 8 0 Probable zinc-ribbon domain zf-ribbon_3 PF13248.6 KFR07056.1 - 0.0017 17.7 28.7 0.48 9.9 0.2 7.6 8 0 0 8 8 8 1 zinc-ribbon domain DUF2072 PF09845.9 KFR07056.1 - 0.0019 18.5 29.4 0.2 11.9 0.3 7.1 6 2 2 8 8 8 1 Zn-ribbon containing protein Zn-C2H2_12 PF18112.1 KFR07056.1 - 0.0024 18.3 23.1 0.31 11.6 0.1 7.3 8 0 0 8 8 7 1 Autophagy receptor zinc finger-C2H2 domain DUF2256 PF10013.9 KFR07056.1 - 0.0031 17.6 23.6 10 6.3 0.1 7.9 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF3268 PF11672.8 KFR07056.1 - 0.0053 17.1 21.6 0.95 9.8 0.4 4.8 1 1 1 5 5 5 3 zinc-finger-containing domain TFIIS_C PF01096.18 KFR07056.1 - 0.011 15.5 39.1 1.4 8.8 0.4 8.0 8 0 0 8 8 8 0 Transcription factor S-II (TFIIS) zinc_ribbon_9 PF14369.6 KFR07056.1 - 0.014 15.6 25.1 6.2 7.2 0.1 7.8 8 0 0 8 8 8 0 zinc-ribbon zf_C2H2_13 PF18508.1 KFR07056.1 - 0.015 14.8 13.1 11 5.7 0.0 6.3 7 0 0 7 7 7 0 Zinc finger domain Zn_ribbon_SprT PF17283.2 KFR07056.1 - 0.02 14.8 0.6 0.02 14.8 0.6 6.5 4 3 2 6 6 6 0 SprT-like zinc ribbon domain zinc-ribbons_6 PF07191.12 KFR07056.1 - 0.024 14.6 33.5 36 4.4 7.4 5.8 1 1 2 3 3 3 0 zinc-ribbons HalOD2 PF18547.1 KFR07056.1 - 0.026 14.4 25.1 0.14 12.1 1.0 6.2 4 2 2 6 6 6 0 Halobacterial output domain 2 zf-H2C2_5 PF13909.6 KFR07056.1 - 0.038 13.7 1.0 0.038 13.7 1.0 10.0 9 4 0 9 9 8 0 C2H2-type zinc-finger domain HNH PF01844.23 KFR07056.1 - 0.058 13.6 33.5 5.1 7.4 0.4 7.9 8 0 0 8 8 8 0 HNH endonuclease Yippee-Mis18 PF03226.14 KFR07056.1 - 0.22 11.7 24.0 8.7 6.6 2.3 5.8 4 2 1 5 5 5 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn_ribbon_recom PF13408.6 KFR07056.1 - 0.23 12.0 31.5 2.7 8.6 0.9 6.5 3 2 1 4 4 4 0 Recombinase zinc beta ribbon domain zf-C2HC_2 PF13913.6 KFR07056.1 - 0.36 10.8 36.9 0.75 9.8 0.2 7.7 8 0 0 8 8 7 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 KFR07056.1 - 0.37 11.2 33.3 0.59 10.5 0.4 6.6 1 1 6 7 7 7 0 C2H2 type zinc-finger (2 copies) Rad50_zn_hook PF04423.14 KFR07056.1 - 0.49 10.3 0.1 0.49 10.3 0.1 4.5 5 0 0 5 5 4 0 Rad50 zinc hook motif zf_C2H2_ZHX PF18387.1 KFR07056.1 - 0.58 9.8 30.1 2.5 7.8 0.3 6.4 1 1 7 8 8 8 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-BED PF02892.15 KFR07056.1 - 0.64 10.1 42.3 0.8 9.8 1.0 7.6 1 1 6 7 7 7 0 BED zinc finger MBD PF01429.19 KFR07056.1 - 1 9.1 5.6 1.1e+02 2.6 5.4 4.2 1 1 1 2 2 2 0 Methyl-CpG binding domain zf-C2HE PF16278.5 KFR07056.1 - 1.5 9.3 43.2 1.4 9.5 0.7 7.7 2 2 6 8 8 8 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_10 PF18414.1 KFR07056.1 - 1.9 8.1 0.0 1.9 8.1 0.0 4.3 5 0 0 5 5 4 0 C2H2 type zinc-finger zinc_ribbon_4 PF13717.6 KFR07056.1 - 2.7 8.0 37.7 18 5.3 0.1 7.7 6 2 1 7 7 7 0 zinc-ribbon domain Sgf11 PF08209.11 KFR07056.1 - 4 7.1 28.6 5.9 6.6 0.1 7.6 8 0 0 8 8 8 0 Sgf11 (transcriptional regulation protein) BolA PF01722.18 KFR07056.1 - 4.5 7.6 17.8 7.3 6.9 0.1 4.7 2 1 2 4 4 3 0 BolA-like protein GAGA PF09237.11 KFR07056.1 - 4.9 7.0 22.4 4.4 7.2 0.3 5.3 1 1 4 6 6 6 0 GAGA factor zf-C2H2_9 PF16293.5 KFR07056.1 - 9.1 6.2 15.2 16 5.5 0.1 5.2 6 1 1 7 7 5 0 C2H2 type zinc-finger (1 copy) PBP_sp32 PF07222.12 KFR07058.1 - 3e-32 112.0 0.9 3.3e-32 111.9 0.9 1.0 1 0 0 1 1 1 1 Proacrosin binding protein sp32 TPR_2 PF07719.17 KFR07059.1 - 2.4e-52 170.9 27.2 5e-06 26.2 0.3 11.5 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_1 PF00515.28 KFR07059.1 - 9.6e-50 164.5 27.3 2.1e-05 24.2 0.1 11.8 11 1 0 11 11 11 10 Tetratricopeptide repeat TPR_11 PF13414.6 KFR07059.1 - 6.6e-43 144.1 27.1 8.9e-09 34.9 0.5 10.7 5 4 6 11 11 11 8 TPR repeat TPR_8 PF13181.6 KFR07059.1 - 2.2e-40 133.5 18.9 0.00044 20.2 0.1 11.2 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_16 PF13432.6 KFR07059.1 - 1.8e-39 134.1 11.6 3.2e-06 27.7 0.3 7.5 6 1 1 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.6 KFR07059.1 - 1.2e-38 128.7 18.9 0.00092 19.4 0.2 12.2 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_14 PF13428.6 KFR07059.1 - 5e-38 126.5 12.5 2.1e-05 25.0 0.4 11.2 3 2 8 11 11 11 7 Tetratricopeptide repeat TPR_12 PF13424.6 KFR07059.1 - 1.2e-34 118.4 26.5 4e-06 27.0 0.8 8.6 2 2 6 8 8 8 8 Tetratricopeptide repeat TPR_19 PF14559.6 KFR07059.1 - 5.3e-33 113.3 18.9 9.8e-10 38.8 0.2 8.7 6 3 1 7 7 7 5 Tetratricopeptide repeat DUF1736 PF08409.11 KFR07059.1 - 1.7e-31 108.0 1.5 4.7e-31 106.6 1.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_10 PF13374.6 KFR07059.1 - 3.4e-25 87.2 28.3 0.00013 21.7 0.1 11.1 10 2 1 11 11 11 6 Tetratricopeptide repeat TPR_7 PF13176.6 KFR07059.1 - 5.1e-20 70.0 16.8 0.0036 17.2 0.0 9.9 10 1 1 11 11 10 5 Tetratricopeptide repeat TPR_15 PF13429.6 KFR07059.1 - 3.5e-18 65.8 7.6 4.4e-10 39.2 1.0 5.0 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFR07059.1 - 7.2e-14 51.7 7.0 0.011 15.9 0.0 5.8 3 1 2 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFR07059.1 - 4.5e-11 42.8 15.5 1.2e-06 28.7 0.3 5.3 3 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 KFR07059.1 - 4.5e-10 39.2 0.0 1.1 10.1 0.0 7.7 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFR07059.1 - 6.7e-09 35.8 16.7 2 9.2 0.0 9.5 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFR07059.1 - 1.1e-08 34.9 10.7 0.0056 16.1 3.7 4.8 1 1 2 4 4 4 3 MalT-like TPR region FAT PF02259.23 KFR07059.1 - 3.5e-08 33.0 5.9 0.0025 17.1 0.2 2.8 2 1 1 3 3 3 2 FAT domain TPR_5 PF12688.7 KFR07059.1 - 4.9e-07 30.0 6.4 0.014 15.6 0.3 4.3 2 2 0 4 4 4 2 Tetratrico peptide repeat ChAPs PF09295.10 KFR07059.1 - 1e-05 24.7 0.2 0.0073 15.3 0.1 2.6 3 0 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) NARP1 PF12569.8 KFR07059.1 - 1.8e-05 23.9 5.7 0.019 13.9 5.7 3.5 1 1 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 KFR07059.1 - 0.00013 22.2 7.2 0.96 9.8 0.2 5.4 4 2 4 8 8 7 2 Tetratricopeptide repeat ANAPC5 PF12862.7 KFR07059.1 - 0.00024 21.1 2.9 1.5 8.9 0.0 4.6 2 1 1 4 4 4 1 Anaphase-promoting complex subunit 5 Coatomer_E PF04733.14 KFR07059.1 - 0.00034 20.1 4.7 0.76 9.1 0.0 3.8 2 1 2 4 4 4 2 Coatomer epsilon subunit BTAD PF03704.17 KFR07059.1 - 0.00096 19.6 8.2 0.06 13.8 1.9 3.1 1 1 0 2 2 2 2 Bacterial transcriptional activator domain PPR PF01535.20 KFR07059.1 - 0.0024 18.0 2.4 16 6.0 0.0 5.3 6 0 0 6 6 3 0 PPR repeat TPR_3 PF07720.12 KFR07059.1 - 0.003 17.5 12.3 0.0032 17.4 0.0 4.9 5 0 0 5 5 3 1 Tetratricopeptide repeat DUF627 PF04781.12 KFR07059.1 - 0.0068 16.4 4.9 4.2 7.4 0.5 5.0 3 2 1 5 5 5 1 Protein of unknown function (DUF627) SNAP PF14938.6 KFR07059.1 - 0.0072 15.8 9.5 0.21 11.0 3.4 3.9 2 1 0 3 3 3 1 Soluble NSF attachment protein, SNAP Sel1 PF08238.12 KFR07059.1 - 0.008 16.8 1.5 25 5.7 0.0 5.3 5 1 1 6 6 4 0 Sel1 repeat Mad3_BUB1_I PF08311.12 KFR07059.1 - 0.016 15.2 7.4 0.019 14.9 0.0 4.1 4 1 0 4 4 4 0 Mad3/BUB1 homology region 1 Rapsyn_N PF10579.9 KFR07059.1 - 0.026 14.6 1.5 3.7 7.7 0.0 3.9 4 0 0 4 4 4 0 Rapsyn N-terminal myristoylation and linker region DUF3856 PF12968.7 KFR07059.1 - 0.031 14.3 1.1 11 6.0 0.1 4.4 2 2 1 4 4 4 0 Domain of Unknown Function (DUF3856) Wzy_C_2 PF11846.8 KFR07059.1 - 0.053 13.4 20.5 0.91 9.4 0.3 6.4 4 1 3 8 8 6 0 Virulence factor membrane-bound polymerase, C-terminal Alkyl_sulf_dimr PF14863.6 KFR07059.1 - 0.062 13.8 1.5 0.093 13.2 0.3 1.9 2 0 0 2 2 1 0 Alkyl sulfatase dimerisation Fis1_TPR_C PF14853.6 KFR07059.1 - 0.12 12.5 8.9 12 6.0 0.2 4.4 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat HTH_Bact PF18768.1 KFR07059.1 - 0.15 11.7 0.2 21 4.8 0.1 3.2 2 1 1 3 3 3 0 Helix-turn-helix bacterial domain DUF2225 PF09986.9 KFR07059.1 - 0.15 11.8 5.9 9.9 5.8 0.0 4.0 1 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) RPN6_N PF18055.1 KFR07059.1 - 0.24 11.8 2.2 3.8 7.9 0.0 3.6 1 1 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain DUF4810 PF16068.5 KFR07059.1 - 0.71 10.5 3.7 75 4.0 0.0 4.5 5 1 1 6 6 3 0 Domain of unknown function (DUF4810) Vps39_1 PF10366.9 KFR07059.1 - 1.2 9.4 3.7 11 6.3 0.1 3.3 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 IBN_N PF03810.19 KFR07060.1 - 5.7e-19 67.8 0.0 1.1e-16 60.5 0.0 3.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 KFR07060.1 - 4.5e-09 35.6 3.5 4.5e-09 35.6 3.5 3.0 2 1 0 3 3 3 1 Cse1 GRP PF07172.11 KFR07060.1 - 0.00053 20.6 4.6 0.0013 19.4 4.6 1.6 1 0 0 1 1 1 1 Glycine rich protein family DUF1539 PF07560.11 KFR07060.1 - 0.0077 16.3 1.9 0.24 11.5 0.1 3.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1539) Cwf_Cwc_15 PF04889.12 KFR07060.1 - 0.042 13.6 2.9 0.084 12.6 2.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Xpo1 PF08389.12 KFR07060.1 - 0.11 12.6 11.2 0.078 13.0 0.5 4.2 4 1 0 4 4 4 0 Exportin 1-like protein FYDLN_acid PF09538.10 KFR07060.1 - 0.12 13.1 2.0 0.29 11.8 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) RTP1_C1 PF10363.9 KFR07060.1 - 0.15 12.2 1.7 4 7.7 0.1 3.5 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF5367 PF17329.2 KFR07060.1 - 0.27 11.4 1.4 2.8 8.1 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5367) BUD22 PF09073.10 KFR07060.1 - 0.49 9.7 2.9 0.98 8.7 2.9 1.4 1 0 0 1 1 1 0 BUD22 TT_ORF2 PF02957.15 KFR07060.1 - 3.6 8.5 9.6 8.4 7.3 9.6 1.5 1 0 0 1 1 1 0 TT viral ORF2 Caprin-1_C PF12287.8 KFR07061.1 - 2e-118 396.4 28.9 2e-118 396.4 28.9 3.3 3 1 0 3 3 3 1 Cytoplasmic activation/proliferation-associated protein-1 C term Caprin-1_dimer PF18293.1 KFR07061.1 - 9.4e-39 132.5 0.2 2.7e-38 131.0 0.2 1.9 1 0 0 1 1 1 1 Caprin-1 dimerization domain C1q PF00386.21 KFR07061.1 - 4.3e-33 114.2 0.0 9e-33 113.2 0.0 1.6 1 0 0 1 1 1 1 C1q domain FAM60A PF15396.6 KFR07062.1 - 8.6e-83 277.5 10.4 1.1e-82 277.2 10.4 1.1 1 0 0 1 1 1 1 Protein Family FAM60A DENN PF02141.21 KFR07063.1 - 4.8e-63 212.5 5.0 1.5e-62 210.9 3.8 2.2 2 0 0 2 2 2 1 DENN (AEX-3) domain RUN PF02759.19 KFR07063.1 - 4.1e-41 140.1 6.0 3e-20 72.6 3.3 2.9 3 0 0 3 3 3 2 RUN domain dDENN PF03455.19 KFR07063.1 - 9.7e-18 63.9 1.6 9.7e-18 63.9 1.6 2.3 2 0 0 2 2 2 1 dDENN domain uDENN PF03456.18 KFR07063.1 - 5.8e-14 52.6 0.0 1.6e-13 51.2 0.0 1.8 1 0 0 1 1 1 1 uDENN domain PLAT PF01477.23 KFR07063.1 - 1.7e-11 44.7 0.0 3.3e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain PrmA PF06325.13 KFR07064.1 - 2.5e-10 40.2 0.1 3.6e-10 39.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KFR07064.1 - 2.1e-08 34.1 0.0 6.2e-08 32.6 0.0 1.7 1 1 0 1 1 1 1 Lysine methyltransferase Met_10 PF02475.16 KFR07064.1 - 0.00019 21.2 0.0 0.00033 20.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 KFR07064.1 - 0.0068 16.0 0.0 0.0095 15.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 KFR07064.1 - 0.036 13.7 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 KFR07064.1 - 0.16 12.7 0.0 0.29 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain LRR_6 PF13516.6 KFR07065.1 - 5.1e-13 47.9 11.3 0.025 14.6 0.0 7.2 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.7 KFR07065.1 - 3.6e-05 24.0 7.6 0.0053 17.2 1.1 4.4 4 1 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFR07065.1 - 0.0073 16.7 4.8 89 4.3 0.1 5.3 4 2 0 4 4 4 0 Leucine Rich Repeat zf_CCCH_4 PF18345.1 KFR07065.1 - 2 8.6 0.0 2 8.6 0.0 3.5 5 0 0 5 5 5 0 Zinc finger domain DUF4617 PF15395.6 KFR07066.1 - 0 1111.2 104.4 0 1111.2 104.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4617) BicD PF09730.9 KFR07067.1 - 0 1149.8 63.8 0 1149.8 63.8 1.9 2 0 0 2 2 2 1 Microtubule-associated protein Bicaudal-D Bap31_Bap29_C PF18035.1 KFR07067.1 - 0.00011 22.1 4.3 0.00011 22.1 4.3 8.7 8 2 0 8 8 8 1 Bap31/Bap29 cytoplasmic coiled-coil domain Med4 PF10018.9 KFR07067.1 - 0.00065 19.4 1.4 0.00065 19.4 1.4 5.7 5 2 0 5 5 5 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF1759 PF03564.15 KFR07067.1 - 0.0032 17.4 5.9 0.0032 17.4 5.9 5.8 4 2 0 6 6 6 1 Protein of unknown function (DUF1759) HALZ PF02183.18 KFR07067.1 - 0.011 15.9 2.4 0.011 15.9 2.4 9.2 8 1 1 9 9 9 0 Homeobox associated leucine zipper Spc7 PF08317.11 KFR07067.1 - 5.2 5.9 96.8 0.27 10.1 8.1 6.2 4 2 1 5 5 5 0 Spc7 kinetochore protein ApoO PF09769.9 KFR07067.1 - 7.5 6.5 17.8 0.15 12.0 0.7 4.5 4 2 0 4 4 4 0 Apolipoprotein O RhoGEF PF00621.20 KFR07068.1 - 3e-46 158.0 0.4 3e-46 158.0 0.4 1.8 2 0 0 2 2 1 1 RhoGEF domain PH PF00169.29 KFR07068.1 - 7.1e-26 90.8 0.4 9.7e-13 48.6 0.0 3.3 2 1 1 3 3 3 2 PH domain FYVE PF01363.21 KFR07068.1 - 3.4e-18 65.5 11.1 9.2e-18 64.2 11.1 1.8 1 0 0 1 1 1 1 FYVE zinc finger IQ_SEC7_PH PF16453.5 KFR07068.1 - 6.1e-08 32.7 0.4 1.1e-06 28.7 0.3 2.4 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 KFR07068.1 - 5.2e-05 23.1 7.7 0.014 15.2 3.1 3.9 3 1 0 3 3 3 1 Pleckstrin homology domain PH_6 PF15406.6 KFR07068.1 - 0.00066 19.9 0.0 1.4 9.2 0.0 2.7 2 0 0 2 2 2 2 Pleckstrin homology domain PH_2 PF08458.10 KFR07068.1 - 0.0026 18.1 0.3 0.75 10.2 0.1 3.2 3 0 0 3 3 3 1 Plant pleckstrin homology-like region PH_11 PF15413.6 KFR07068.1 - 0.0029 18.0 1.2 1.2 9.6 0.0 3.8 2 1 0 2 2 2 1 Pleckstrin homology domain FYVE_2 PF02318.16 KFR07068.1 - 0.0032 17.7 13.0 0.016 15.4 12.0 2.7 1 1 1 2 2 2 1 FYVE-type zinc finger Presenilin PF01080.17 KFR07068.1 - 0.053 12.3 1.1 0.096 11.4 1.1 1.4 1 0 0 1 1 1 0 Presenilin PH_5 PF15405.6 KFR07068.1 - 0.065 13.3 0.3 7.2 6.7 0.1 3.1 1 1 1 2 2 2 0 Pleckstrin homology domain zf-RING_UBOX PF13445.6 KFR07068.1 - 0.11 12.5 6.4 0.078 13.0 3.8 2.1 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.6 KFR07068.1 - 0.21 11.5 12.7 0.51 10.3 12.7 1.7 1 0 0 1 1 1 0 zinc-RING finger domain PH_16 PF17838.1 KFR07068.1 - 0.23 11.3 2.2 3.3 7.6 0.1 2.8 3 0 0 3 3 3 0 PH domain DUF4162 PF13732.6 KFR07068.1 - 1.3 9.8 5.6 2 9.2 0.1 3.4 4 0 0 4 4 3 0 Domain of unknown function (DUF4162) IBR PF01485.21 KFR07068.1 - 5.1 7.4 13.6 0.66 10.2 8.1 2.4 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Dynamin_M PF01031.20 KFR07069.1 - 1.6e-104 349.1 0.0 1e-103 346.5 0.0 2.1 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KFR07069.1 - 1.9e-54 184.2 1.0 3.4e-54 183.4 0.2 1.8 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 KFR07069.1 - 1.9e-31 108.1 2.7 1.9e-31 108.1 2.7 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KFR07069.1 - 1.8e-05 24.8 0.3 0.00015 21.8 0.3 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFR07069.1 - 0.0014 19.1 0.2 0.017 15.5 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_28 PF13521.6 KFR07069.1 - 0.046 14.0 0.5 0.36 11.0 0.1 2.4 1 1 1 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KFR07069.1 - 0.068 12.5 0.1 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Arm PF00514.23 KFR07070.1 - 4.6e-29 99.5 0.7 5.6e-08 32.6 0.0 6.6 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 KFR07070.1 - 1.1e-06 28.4 0.6 0.0023 17.5 0.1 2.8 2 1 1 3 3 3 2 Armadillo-like Atx10homo_assoc PF09759.9 KFR07070.1 - 0.001 19.1 0.0 0.036 14.1 0.0 2.8 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 KFR07070.1 - 0.13 12.7 0.1 1.6 9.1 0.0 2.5 2 0 0 2 2 2 0 HEAT repeats Symplekin_C PF12295.8 KFR07070.1 - 0.14 12.2 0.1 18 5.3 0.0 3.0 3 0 0 3 3 3 0 Symplekin tight junction protein C terminal HEAT PF02985.22 KFR07070.1 - 0.14 12.5 0.2 7 7.2 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat C2 PF00168.30 KFR07071.1 - 2.4e-53 178.7 0.1 4.2e-27 94.4 0.0 2.3 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 KFR07071.1 - 2.3e-05 24.4 0.2 0.24 11.3 0.0 3.2 3 1 0 3 3 3 2 Phosphoinositide 3-kinase C2 CEP76-C2 PF15627.6 KFR07071.1 - 0.0035 16.9 0.0 1.2 8.7 0.0 2.6 3 0 0 3 3 3 2 CEP76 C2 domain Na_sulph_symp PF00939.19 KFR07072.1 - 5.2e-96 322.5 17.7 6.2e-96 322.3 17.7 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KFR07072.1 - 2.8e-34 118.7 18.9 4.2e-17 62.3 0.0 3.1 2 1 1 3 3 3 3 Citrate transporter SbmA_BacA PF05992.12 KFR07072.1 - 1.4 8.3 8.1 3.3 7.1 1.9 2.4 2 0 0 2 2 2 0 SbmA/BacA-like family FAM180 PF15173.6 KFR07073.1 - 2.7e-61 205.5 0.4 3.1e-61 205.4 0.4 1.0 1 0 0 1 1 1 1 FAM180 family Fox-1_C PF12414.8 KFR07073.1 - 0.13 12.7 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 Calcitonin gene-related peptide regulator C terminal Ank_5 PF13857.6 KFR07074.1 - 1.2e-17 63.7 0.0 3.4e-10 40.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFR07074.1 - 2.3e-17 63.1 0.1 4.3e-12 46.3 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFR07074.1 - 2.5e-14 53.6 0.1 3.2e-13 50.1 0.0 2.2 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFR07074.1 - 1.1e-13 51.0 0.1 9.2e-07 29.0 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFR07074.1 - 2.9e-12 45.6 0.1 7e-07 29.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat KOW PF00467.29 KFR07083.1 - 4.4e-18 64.6 5.2 8.3e-05 22.4 0.1 5.0 5 0 0 5 5 5 4 KOW motif Spt5_N PF11942.8 KFR07083.1 - 3.8e-14 53.5 6.7 3.8e-14 53.5 6.7 2.4 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal Spt5-NGN PF03439.13 KFR07083.1 - 6.9e-06 25.9 0.1 0.00035 20.4 0.1 2.4 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section DUF3912 PF13051.6 KFR07083.1 - 7.9e-05 22.8 1.2 0.0011 19.2 0.0 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF3912) FtsJ PF01728.19 KFR07083.1 - 0.098 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase CDC45 PF02724.14 KFR07083.1 - 3 6.0 16.6 4.1 5.6 16.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Helicase_C_2 PF13307.6 KFR07084.1 - 3.1e-46 157.6 0.1 7.4e-46 156.4 0.1 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 KFR07084.1 - 4.9e-45 153.6 0.3 1.6e-40 138.8 0.0 2.6 2 0 0 2 2 2 2 Helical and beta-bridge domain DEAD_2 PF06733.15 KFR07084.1 - 1.2e-28 100.0 0.5 1.1e-15 57.7 0.5 2.4 1 1 1 2 2 2 2 DEAD_2 ResIII PF04851.15 KFR07084.1 - 6.5e-08 32.8 0.0 1.5e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFR07084.1 - 0.00017 21.4 0.1 0.00031 20.6 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SesA PF17107.5 KFR07084.1 - 0.00073 19.7 0.2 0.01 16.1 0.1 2.4 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF4525 PF15027.6 KFR07084.1 - 0.012 15.3 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) AAA_22 PF13401.6 KFR07084.1 - 0.017 15.4 0.9 0.17 12.1 0.1 3.0 2 1 0 2 2 2 0 AAA domain SNF2_N PF00176.23 KFR07084.1 - 0.052 12.3 0.2 0.26 10.0 0.1 1.9 1 1 0 1 1 1 0 SNF2 family N-terminal domain AAA_19 PF13245.6 KFR07084.1 - 0.16 12.3 0.0 1.2 9.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain ATP-gua_Ptrans PF00217.19 KFR07085.1 - 3.4e-37 128.0 0.0 5.2e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 KFR07085.1 - 1.8e-16 60.2 0.0 3.2e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain TRAF6_Z2 PF18048.1 KFR07085.1 - 3.9 7.6 14.3 0.25 11.4 1.4 3.3 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 Sec6 PF06046.13 KFR07086.1 - 8.6e-37 126.7 0.0 9.5e-37 126.6 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec6 Prefoldin_2 PF01920.20 KFR07087.1 - 0.11 12.4 3.9 0.14 12.1 3.9 1.1 1 0 0 1 1 1 0 Prefoldin subunit DivIC PF04977.15 KFR07087.1 - 0.13 12.1 3.9 0.17 11.7 3.9 1.1 1 0 0 1 1 1 0 Septum formation initiator DUF3450 PF11932.8 KFR07087.1 - 0.14 11.4 1.5 0.19 11.0 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 KFR07087.1 - 0.45 11.0 7.9 0.62 10.6 7.9 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region bZIP_2 PF07716.15 KFR07087.1 - 2.3 8.3 6.3 3 8.0 6.3 1.1 1 0 0 1 1 1 0 Basic region leucine zipper F-box-like PF12937.7 KFR07088.1 - 1e-06 28.5 0.1 8.3e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 F-box-like BTK PF00779.19 KFR07088.1 - 5.3e-05 22.9 0.2 0.00015 21.5 0.2 1.8 1 0 0 1 1 1 1 BTK motif F-box PF00646.33 KFR07088.1 - 0.00045 20.0 0.0 0.0009 19.1 0.0 1.4 1 0 0 1 1 1 1 F-box domain Peptidase_M28 PF04389.17 KFR07089.1 - 0.022 14.5 0.0 0.025 14.3 0.0 1.0 1 0 0 1 1 1 0 Peptidase family M28 Pkinase PF00069.25 KFR07090.1 - 1.8e-77 260.3 0.0 2.3e-77 259.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR07090.1 - 4.9e-37 127.6 0.0 7.2e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KFR07090.1 - 1.9e-10 41.3 2.7 4.2e-10 40.2 2.7 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFR07090.1 - 2.4e-10 40.2 0.0 2.7e-09 36.8 0.0 2.3 2 1 1 3 3 3 1 Kinase-like PH PF00169.29 KFR07090.1 - 9.9e-09 35.7 0.2 2.8e-08 34.2 0.2 1.8 1 1 0 1 1 1 1 PH domain DUF5577 PF17740.1 KFR07091.1 - 1.6e-117 392.4 13.0 2.1e-117 392.0 13.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5577) SAM_4 PF18017.1 KFR07091.1 - 5.1e-55 183.4 0.5 8e-55 182.7 0.5 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFR07091.1 - 0.0017 18.4 0.1 0.0051 16.9 0.1 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFR07091.1 - 0.043 14.3 0.0 0.089 13.2 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PLDc_3 PF13918.6 KFR07092.1 - 1.1e-36 126.1 0.0 8.1e-36 123.3 0.0 2.0 2 0 0 2 2 2 1 PLD-like domain PLDc_2 PF13091.6 KFR07092.1 - 1e-28 99.8 0.0 6e-17 61.8 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KFR07092.1 - 9.8e-12 44.6 3.9 1.2e-08 34.8 0.8 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif AMP-binding PF00501.28 KFR07093.1 - 2.8e-69 233.7 0.0 3.5e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFR07093.1 - 8.1e-10 39.6 0.2 2.9e-09 37.8 0.0 2.1 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Beach PF02138.18 KFR07094.1 - 2.5e-121 404.3 1.0 3.9e-121 403.7 1.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 KFR07094.1 - 1.5e-110 368.9 2.3 1.5e-110 368.9 2.3 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) DUF1088 PF06469.11 KFR07094.1 - 4.9e-88 293.1 9.0 4.9e-88 293.1 9.0 2.1 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1088) PH_BEACH PF14844.6 KFR07094.1 - 5.7e-30 103.4 0.7 2.7e-29 101.2 0.0 2.5 3 0 0 3 3 3 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 KFR07094.1 - 1.4e-11 44.8 0.0 4.3e-11 43.2 0.0 1.9 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 KFR07094.1 - 5.3e-06 27.1 11.5 1.1 10.2 0.3 7.1 7 0 0 7 7 7 2 WD domain, G-beta repeat PIGA PF08288.12 KFR07094.1 - 0.045 14.3 0.4 0.16 12.5 0.4 2.0 1 0 0 1 1 1 0 PIGA (GPI anchor biosynthesis) RTP1_C1 PF10363.9 KFR07094.1 - 0.18 12.0 0.7 1.3 9.2 0.3 2.5 1 1 1 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 VHS PF00790.19 KFR07094.1 - 0.19 11.6 0.7 7.3 6.4 0.0 3.4 3 0 0 3 3 3 0 VHS domain Mab-21 PF03281.14 KFR07095.1 - 1.8e-98 329.5 0.0 2.3e-98 329.2 0.0 1.1 1 0 0 1 1 1 1 Mab-21 protein Pentapeptide_4 PF13599.6 KFR07096.1 - 0.004 17.3 0.0 1.1 9.4 0.0 2.0 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) DUF2924 PF11149.8 KFR07096.1 - 0.62 10.4 3.9 3.2 8.1 3.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2924) RVT_1 PF00078.27 KFR07097.1 - 0.0061 16.1 0.0 0.022 14.3 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol3_delta2 PF13177.6 KFR07099.1 - 4.6e-10 39.5 1.0 5.4e-10 39.3 0.1 1.5 2 0 0 2 2 2 1 DNA polymerase III, delta subunit DNA_pol3_delta PF06144.13 KFR07099.1 - 8.5e-06 25.6 0.3 1.6e-05 24.8 0.3 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KFR07099.1 - 1.2e-05 25.8 0.0 2.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFR07099.1 - 0.0022 18.3 0.2 0.011 16.0 0.1 2.1 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 KFR07099.1 - 0.0051 16.7 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KFR07099.1 - 0.0057 17.0 0.1 0.021 15.2 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 KFR07099.1 - 0.012 16.2 0.0 0.021 15.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Phasin_2 PF09361.10 KFR07099.1 - 0.019 15.2 0.3 22 5.4 0.0 3.4 4 0 0 4 4 4 0 Phasin protein Rep_fac_C PF08542.11 KFR07099.1 - 0.026 14.9 0.0 0.1 13.0 0.0 2.1 2 0 0 2 2 2 0 Replication factor C C-terminal domain DUF2247 PF10004.9 KFR07099.1 - 0.042 13.6 0.2 0.071 12.9 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) ATPgrasp_ST PF14397.6 KFR07099.1 - 0.052 12.8 0.1 0.13 11.5 0.1 1.5 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Yae1_N PF09811.9 KFR07100.1 - 1.8e-13 49.9 43.9 1.8e+04 -8.7 43.9 4.2 1 1 0 1 1 1 0 Essential protein Yae1, N terminal START PF01852.19 KFR07102.1 - 1.3e-42 145.5 0.4 2.4e-42 144.7 0.4 1.4 1 0 0 1 1 1 1 START domain RhoGAP PF00620.27 KFR07102.1 - 4.5e-36 124.0 0.6 9.1e-36 123.0 0.6 1.5 1 0 0 1 1 1 1 RhoGAP domain Glyco_hydro_1 PF00232.18 KFR07103.1 - 2.2e-166 553.8 15.2 9.3e-77 258.4 6.4 4.0 2 2 1 3 3 3 3 Glycosyl hydrolase family 1 Lipase_GDSL_2 PF13472.6 KFR07103.1 - 0.063 13.7 0.0 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Cnd1 PF12717.7 KFR07105.1 - 0.0031 17.5 17.2 0.31 11.1 0.3 6.1 4 2 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Hepatitis_core PF00906.20 KFR07105.1 - 0.0054 16.3 0.6 0.058 12.9 0.0 2.6 3 0 0 3 3 3 1 Hepatitis core antigen HEAT PF02985.22 KFR07105.1 - 0.0061 16.7 4.1 1.7 9.1 0.0 5.6 6 0 0 6 6 6 1 HEAT repeat PI-TkoII_IV PF18714.1 KFR07105.1 - 0.049 13.1 0.0 0.17 11.4 0.0 1.9 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV FANCI_S2 PF14676.6 KFR07105.1 - 0.22 11.8 2.8 3.6 7.9 0.1 3.6 2 1 1 3 3 3 0 FANCI solenoid 2 HEAT_EZ PF13513.6 KFR07105.1 - 0.3 11.6 2.3 1.5e+02 3.0 0.0 4.9 6 0 0 6 6 6 0 HEAT-like repeat Nipped-B_C PF12830.7 KFR07105.1 - 3.7 7.5 5.9 15 5.5 0.0 4.2 5 1 0 5 5 5 0 Sister chromatid cohesion C-terminus AAA_33 PF13671.6 KFR07107.1 - 1.2e-17 64.4 0.0 2.7e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFR07107.1 - 4.2e-06 26.2 0.0 3.3e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 KFR07107.1 - 0.00017 22.1 0.0 0.00063 20.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KFR07107.1 - 0.00036 20.1 1.5 0.0012 18.4 0.1 2.5 2 1 0 2 2 2 1 Chromatin associated protein KTI12 ABC_tran PF00005.27 KFR07107.1 - 0.011 16.3 0.1 0.052 14.1 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 KFR07107.1 - 0.046 14.1 0.0 0.099 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Tmemb_cc2 PF10267.9 KFR07107.1 - 0.12 11.5 6.0 0.21 10.7 6.0 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF3324 PF11797.8 KFR07108.1 - 0.032 14.2 0.1 0.044 13.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function C-terminal (DUF3324) MACPF PF01823.19 KFR07131.1 - 7.4e-07 29.5 0.1 3.7e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 MAC/Perforin domain Pentapeptide_4 PF13599.6 KFR07133.1 - 0.015 15.4 0.0 1.2 9.4 0.0 1.9 1 1 1 2 2 2 0 Pentapeptide repeats (9 copies) FliT PF05400.13 KFR07148.1 - 0.11 13.3 4.3 11 6.9 0.2 3.2 3 0 0 3 3 3 0 Flagellar protein FliT 7tm_1 PF00001.21 KFR07149.1 - 1.4e-75 254.1 8.0 1.8e-75 253.7 8.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFR07149.1 - 1.4e-09 38.0 9.0 1.4e-09 38.0 9.0 1.9 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFR07149.1 - 8.3e-06 25.7 13.4 1.9e-05 24.5 3.4 2.5 2 1 0 3 3 3 2 Olfactory receptor Fibrinogen_C PF00147.18 KFR07150.1 - 6.7e-22 78.4 0.1 7.3e-22 78.3 0.1 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF2012 PF09430.10 KFR07151.1 - 2.8e-30 105.0 0.0 3.6e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) Katanin_con80 PF13925.6 KFR07152.1 - 1e-35 123.1 0.0 1.6e-35 122.5 0.0 1.3 1 0 0 1 1 1 1 con80 domain of Katanin Yae1_N PF09811.9 KFR07153.1 - 9.6e-10 38.0 28.0 4.6 7.0 28.0 3.1 1 1 0 1 1 1 1 Essential protein Yae1, N terminal TSP_C PF05735.12 KFR07154.1 - 3.7e-69 232.6 0.7 5.3e-69 232.1 0.7 1.2 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.18 KFR07154.1 - 1.5e-57 190.9 157.1 2.6e-12 46.2 13.6 10.4 9 2 2 11 11 11 9 Thrombospondin type 3 repeat TSP_1 PF00090.19 KFR07154.1 - 6.4e-40 135.1 47.1 5e-16 58.7 8.5 5.1 6 0 0 6 6 6 3 Thrombospondin type 1 domain VWC PF00093.18 KFR07154.1 - 1.3e-12 47.9 17.8 1.3e-12 47.9 17.8 6.7 4 3 2 6 6 6 1 von Willebrand factor type C domain EGF_3 PF12947.7 KFR07154.1 - 1.4e-06 28.4 10.5 1.4e-06 28.4 10.5 6.2 5 0 0 5 5 5 2 EGF domain cEGF PF12662.7 KFR07154.1 - 1.8e-06 27.7 24.0 2e-06 27.6 1.2 5.1 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF_CA PF07645.15 KFR07154.1 - 1.4e-05 25.2 1.6 1.4e-05 25.2 1.6 5.9 5 0 0 5 5 5 3 Calcium-binding EGF domain Laminin_G_3 PF13385.6 KFR07154.1 - 0.00014 22.0 0.7 0.0014 18.8 0.0 2.2 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 KFR07154.1 - 0.0013 19.0 11.8 0.0013 19.0 11.8 7.0 6 1 1 7 7 7 2 EGF-like domain Laminin_G_2 PF02210.24 KFR07154.1 - 0.0023 18.5 0.2 0.005 17.4 0.2 1.4 1 0 0 1 1 1 1 Laminin G domain Ham1p_like PF01725.16 KFR07155.1 - 0.095 12.6 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Ham1 family FSIP1 PF15554.6 KFR07156.1 - 4.3e-31 108.4 5.0 5.5e-31 108.1 5.0 1.1 1 0 0 1 1 1 1 FSIP1 family 7tm_1 PF00001.21 KFR07157.1 - 7.4e-30 104.1 28.9 9.8e-30 103.8 28.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pkinase PF00069.25 KFR07158.1 - 3.2e-79 266.0 1.9 2.6e-35 122.1 0.0 4.7 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KFR07158.1 - 9.5e-47 159.4 1.3 5.9e-19 68.3 0.4 5.2 3 2 0 3 3 3 3 Protein tyrosine kinase HGTP_anticodon2 PF12745.7 KFR07158.1 - 6.9e-17 61.8 0.2 6.9e-17 61.8 0.2 2.4 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_His PF13393.6 KFR07158.1 - 4.1e-15 55.8 0.2 9.6e-15 54.6 0.0 1.7 2 0 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.22 KFR07158.1 - 2.2e-14 53.8 0.0 1.3e-13 51.2 0.0 2.5 1 0 0 1 1 1 1 RWD domain Kinase-like PF14531.6 KFR07158.1 - 3.1e-05 23.4 0.0 0.064 12.6 0.0 2.7 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KFR07158.1 - 0.00066 19.1 0.3 0.57 9.5 0.1 2.6 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFR07158.1 - 0.0095 15.9 0.1 0.041 13.8 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family SRP14 PF02290.15 KFR07159.1 - 9.9e-25 86.7 0.1 9.9e-25 86.7 0.1 1.5 2 0 0 2 2 2 1 Signal recognition particle 14kD protein DUF3509 PF12021.8 KFR07159.1 - 0.093 12.5 0.0 1.4 8.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3509) BMF PF15185.6 KFR07160.1 - 1.8e-115 383.4 1.2 2.1e-115 383.2 1.2 1.0 1 0 0 1 1 1 1 Bcl-2-modifying factor, apoptosis MoCF_biosynth PF00994.24 KFR07161.1 - 2.8e-67 224.9 0.0 3e-39 133.9 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KFR07161.1 - 8.4e-42 142.6 1.6 1.5e-41 141.8 0.6 1.9 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KFR07161.1 - 2.2e-23 82.2 0.0 5.8e-23 80.9 0.0 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Tubulin-binding PF00418.19 KFR07161.1 - 0.17 11.9 0.1 0.38 10.8 0.1 1.5 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat Guanylate_kin PF00625.21 KFR07162.1 - 6.4e-52 175.9 0.0 1.5e-51 174.7 0.0 1.6 1 0 0 1 1 1 1 Guanylate kinase L27_N PF09060.10 KFR07162.1 - 4.2e-25 87.5 3.0 1.2e-24 86.1 3.0 1.9 1 0 0 1 1 1 1 L27_N SH3_2 PF07653.17 KFR07162.1 - 2.1e-12 46.5 0.0 4.7e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PDZ PF00595.24 KFR07162.1 - 1.2e-11 44.8 0.6 2.4e-11 43.8 0.6 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFR07162.1 - 2.4e-09 36.9 0.0 6.6e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 PDZ domain L27 PF02828.16 KFR07162.1 - 4.4e-09 36.0 3.0 4.5e-09 35.9 1.1 2.2 2 0 0 2 2 2 1 L27 domain SH3_1 PF00018.28 KFR07162.1 - 1.9e-06 27.3 0.3 7.1e-06 25.5 0.3 2.0 1 1 0 1 1 1 1 SH3 domain PDZ_2 PF13180.6 KFR07162.1 - 6.1e-06 26.5 0.1 1.7e-05 25.0 0.1 1.8 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.6 KFR07162.1 - 0.0003 20.6 0.1 0.00067 19.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain MMR_HSR1 PF01926.23 KFR07162.1 - 0.028 14.5 0.0 0.22 11.6 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SpoU_sub_bind PF08032.12 KFR07162.1 - 0.49 10.7 2.9 16 5.8 0.0 3.9 3 1 1 4 4 4 0 RNA 2'-O ribose methyltransferase substrate binding ATP-synt_D PF01813.17 KFR07163.1 - 4.6e-76 255.0 8.6 6.2e-76 254.6 8.6 1.2 1 0 0 1 1 1 1 ATP synthase subunit D DUF4249 PF14054.6 KFR07163.1 - 0.042 13.5 0.1 0.053 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4249) EIF_2_alpha PF07541.12 KFR07164.1 - 1.1e-36 125.4 0.0 2.2e-36 124.4 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KFR07164.1 - 1.1e-15 57.7 0.7 2.7e-15 56.5 0.7 1.6 1 0 0 1 1 1 1 S1 RNA binding domain SoDot-IcmSS PF16848.5 KFR07164.1 - 0.069 13.1 0.5 0.26 11.3 0.1 2.1 2 0 0 2 2 2 0 Substrate of the Dot/Icm secretion system, putative DUF4453 PF14627.6 KFR07164.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) PH PF00169.29 KFR07165.1 - 1.7e-31 108.9 0.2 8e-15 55.2 0.0 2.7 3 0 0 3 3 3 2 PH domain DEP PF00610.21 KFR07165.1 - 7.4e-17 61.2 0.0 2e-16 59.8 0.0 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_11 PF15413.6 KFR07165.1 - 2.7e-07 30.9 5.4 0.047 14.1 0.6 4.2 3 1 0 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.6 KFR07165.1 - 4.3e-07 30.3 1.3 0.054 13.9 0.1 3.5 3 2 0 3 3 3 2 Pleckstrin homology domain PH_6 PF15406.6 KFR07165.1 - 0.0018 18.5 0.0 0.22 11.8 0.0 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain PH_8 PF15409.6 KFR07165.1 - 0.0023 18.2 0.2 0.23 11.7 0.4 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_2 PF08458.10 KFR07165.1 - 0.019 15.3 0.1 11 6.4 0.0 2.7 3 0 0 3 3 3 0 Plant pleckstrin homology-like region PH_4 PF15404.6 KFR07165.1 - 0.062 13.1 0.0 7 6.4 0.0 2.9 3 0 0 3 3 3 0 Pleckstrin homology domain Gal-bind_lectin PF00337.22 KFR07167.1 - 1.7e-32 111.8 0.0 1.8e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin FYVE PF01363.21 KFR07168.1 - 7e-17 61.3 15.9 1.3e-16 60.4 15.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger MerR-DNA-bind PF09278.11 KFR07168.1 - 0.051 14.1 0.2 0.23 12.0 0.0 2.3 2 0 0 2 2 2 0 MerR, DNA binding FYVE_2 PF02318.16 KFR07168.1 - 0.098 12.9 11.2 0.25 11.6 11.2 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger TPR_2 PF07719.17 KFR07169.1 - 0.00062 19.7 0.3 0.0035 17.3 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Hemocyanin_M PF00372.19 KFR07169.1 - 0.015 14.5 0.3 0.43 9.7 0.1 2.2 2 0 0 2 2 2 0 Hemocyanin, copper containing domain Sigma54_CBD PF04963.13 KFR07169.1 - 0.026 14.4 0.5 0.083 12.7 0.2 1.9 2 0 0 2 2 2 0 Sigma-54 factor, core binding domain adh_short PF00106.25 KFR07170.1 - 4.8e-32 111.0 0.1 3.5e-31 108.2 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFR07170.1 - 6.9e-18 65.1 0.1 1.6e-17 63.8 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFR07170.1 - 1.1e-07 31.9 0.1 1.6e-07 31.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KFR07170.1 - 0.00038 20.7 0.5 0.00066 19.9 0.5 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KFR07170.1 - 0.026 14.0 0.2 0.063 12.7 0.2 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KFR07170.1 - 0.1 12.0 0.1 0.33 10.3 0.0 1.8 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) V-SNARE_C PF12352.8 KFR07171.1 - 3.1e-20 72.2 7.9 3.1e-20 72.2 7.9 2.4 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 KFR07171.1 - 5.4e-13 49.1 5.8 5.4e-13 49.1 5.8 2.2 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 KFR07171.1 - 4.1e-05 23.4 2.1 4.1e-05 23.4 2.1 1.9 2 1 0 2 2 2 1 Sec20 YqjK PF13997.6 KFR07171.1 - 0.0088 16.3 2.8 0.69 10.2 0.0 2.5 3 0 0 3 3 3 1 YqjK-like protein Fusion_gly PF00523.18 KFR07171.1 - 0.038 12.2 2.6 0.061 11.6 2.6 1.4 1 1 0 1 1 1 0 Fusion glycoprotein F0 Laminin_II PF06009.12 KFR07171.1 - 0.043 13.8 4.8 0.067 13.2 0.7 2.3 2 1 0 2 2 2 0 Laminin Domain II Snapin_Pallidin PF14712.6 KFR07171.1 - 0.081 13.4 11.6 0.088 13.2 1.2 2.5 2 1 0 2 2 2 0 Snapin/Pallidin DUF745 PF05335.13 KFR07171.1 - 0.14 11.9 5.6 1.7 8.3 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF3958 PF13125.6 KFR07171.1 - 0.41 10.9 11.0 0.068 13.4 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) HalX PF08663.10 KFR07171.1 - 0.76 10.1 8.3 4.3 7.7 2.1 2.4 2 0 0 2 2 2 0 HalX domain KxDL PF10241.9 KFR07171.1 - 2 8.7 9.3 3.9 7.8 1.3 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein RSS_P20 PF11757.8 KFR07171.1 - 2.2 8.8 7.3 0.7 10.4 1.2 2.2 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain DUF1664 PF07889.12 KFR07171.1 - 8.1 6.5 6.7 14 5.7 1.0 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 KFR07171.1 - 8.7 5.8 9.9 23 4.4 10.0 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit Arginase PF00491.21 KFR07172.1 - 1.9e-65 221.2 0.0 2.2e-65 221.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family ABC_trans_CmpB PF06541.11 KFR07173.1 - 1.9e-09 37.9 11.1 2.4e-09 37.6 11.1 1.1 1 0 0 1 1 1 1 Putative ABC-transporter type IV Rad51 PF08423.11 KFR07175.1 - 3.6e-38 131.3 0.0 4.3e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KFR07175.1 - 2e-10 40.6 0.0 2.6e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KFR07175.1 - 6.6e-08 32.2 0.6 2.6e-07 30.3 0.6 2.0 1 1 0 1 1 1 1 KaiC RecA PF00154.21 KFR07175.1 - 2.1e-05 24.1 0.1 0.033 13.6 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein DnaB_C PF03796.15 KFR07175.1 - 0.00012 21.6 0.1 0.0032 16.8 0.1 2.3 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain DUF5522 PF17653.1 KFR07175.1 - 0.016 15.1 0.1 0.038 13.9 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5522) PAXNEB PF05625.11 KFR07175.1 - 0.018 14.2 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 PAXNEB protein AAA_24 PF13479.6 KFR07175.1 - 0.059 13.1 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KFR07175.1 - 0.085 13.3 0.1 0.35 11.3 0.1 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SAM_2 PF07647.17 KFR07175.1 - 0.13 12.4 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PDGF_N PF04692.13 KFR07175.1 - 0.15 12.9 0.5 0.73 10.7 0.0 2.2 2 1 0 2 2 2 0 Platelet-derived growth factor, N terminal region zf-CCCH PF00642.24 KFR07177.1 - 4.6e-23 80.6 14.8 7.1e-12 44.9 2.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFR07177.1 - 1.2e-11 44.3 15.2 1.4e-06 28.2 2.9 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KFR07177.1 - 2.5e-07 30.3 13.8 2.7e-05 23.8 1.5 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Tis11B_N PF04553.12 KFR07177.1 - 1.8e-05 25.2 0.8 1.8e-05 25.2 0.8 1.7 2 0 0 2 2 2 1 Tis11B like protein, N terminus Torus PF16131.5 KFR07177.1 - 0.0002 22.0 8.5 0.036 14.8 0.8 2.2 1 1 1 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 KFR07177.1 - 0.014 15.8 20.0 0.052 14.0 1.4 2.8 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger oligo_HPY PF08352.12 KFR07177.1 - 1.1 9.8 7.8 3.6 8.2 0.6 2.4 1 1 1 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region RRM_1 PF00076.22 KFR07178.1 - 4.2e-34 116.2 0.1 1.6e-16 59.9 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFR07178.1 - 2e-08 34.2 0.3 8.9e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif RRM_5 PF13893.6 KFR07178.1 - 1.2e-05 24.8 0.0 0.053 13.1 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFR07178.1 - 8.5e-05 22.3 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KFR07178.1 - 0.0071 16.3 0.2 0.066 13.2 0.1 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DbpA PF03880.15 KFR07178.1 - 0.037 14.0 0.1 4.1 7.5 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain SET_assoc PF11767.8 KFR07178.1 - 0.089 12.4 0.1 1 9.1 0.1 2.4 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated CDC45 PF02724.14 KFR07178.1 - 1.3 7.2 13.3 1.5 7.1 13.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KFR07178.1 - 2.3 6.9 8.5 2.7 6.6 8.5 1.1 1 0 0 1 1 1 0 Presenilin Spectrin PF00435.21 KFR07179.1 - 1.3e-74 247.4 25.4 1.1e-25 90.2 6.9 4.3 4 0 0 4 4 4 4 Spectrin repeat CH PF00307.31 KFR07179.1 - 2e-50 169.5 0.1 4.4e-25 88.0 0.0 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KFR07179.1 - 8.2e-27 93.1 0.0 3.4e-26 91.1 0.0 2.2 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_1 PF00036.32 KFR07179.1 - 2.4e-07 29.8 1.0 0.0097 15.4 0.2 3.3 3 0 0 3 3 3 2 EF hand CAMSAP_CH PF11971.8 KFR07179.1 - 9.2e-07 28.6 0.0 5e-05 23.0 0.0 2.6 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_7 PF13499.6 KFR07179.1 - 2e-06 28.1 0.1 1.6e-05 25.3 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KFR07179.1 - 6.6e-05 22.7 1.1 0.002 18.0 0.4 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KFR07179.1 - 0.0003 20.5 1.8 0.03 14.2 0.1 3.8 4 0 0 4 4 3 1 EF-hand domain XisI PF08869.11 KFR07179.1 - 0.0092 16.3 0.9 0.033 14.5 0.9 2.0 1 0 0 1 1 1 1 XisI protein EF-hand_11 PF08976.11 KFR07179.1 - 0.078 13.9 0.2 0.34 11.8 0.1 2.2 2 0 0 2 2 1 0 EF-hand domain Uds1 PF15456.6 KFR07179.1 - 0.29 11.3 11.0 0.16 12.1 2.4 3.5 3 0 0 3 3 3 0 Up-regulated During Septation U3_assoc_6 PF08640.11 KFR07179.1 - 0.81 9.8 4.0 1.5 8.9 0.1 3.3 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 6 WD40 PF00400.32 KFR07180.1 - 1.8e-11 44.4 14.5 0.0047 17.7 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Frtz PF11768.8 KFR07180.1 - 0.059 11.7 0.0 0.09 11.1 0.0 1.1 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz DNA_pol_A_exo1 PF01612.20 KFR07181.1 - 1.2e-16 60.9 0.0 2e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease RRXRR PF14239.6 KFR07181.1 - 0.0069 16.2 0.0 0.032 14.1 0.0 2.0 2 0 0 2 2 2 1 RRXRR protein PP_M1 PF03012.14 KFR07181.1 - 0.02 14.5 0.0 0.029 13.9 0.0 1.1 1 0 0 1 1 1 0 Phosphoprotein Glycos_transf_2 PF00535.26 KFR07182.1 - 2.6e-26 92.5 0.0 4e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFR07182.1 - 4e-18 65.9 2.4 6.9e-18 65.1 2.4 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 KFR07182.1 - 2.3e-08 34.2 0.0 3.9e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KFR07182.1 - 7.2e-07 29.0 0.0 2.2e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KFR07182.1 - 9e-06 25.3 0.1 1.8e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase DUF4227 PF14004.6 KFR07182.1 - 0.089 12.8 0.4 0.16 11.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) DUF4897 PF16238.5 KFR07182.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) ER PF01133.17 KFR07183.1 - 5.9e-46 154.5 0.2 6.7e-46 154.3 0.2 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary BA14K PF07886.11 KFR07183.1 - 0.11 12.4 1.2 0.25 11.3 1.2 1.6 1 0 0 1 1 1 0 BA14K-like protein Zip PF02535.22 KFR07184.1 - 2.8e-39 135.3 20.8 5.8e-29 101.4 11.8 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter 7TM-7TMR_HD PF07698.11 KFR07184.1 - 1.2 8.8 12.1 0.18 11.6 4.8 2.5 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase DUF996 PF06195.13 KFR07184.1 - 5.1 7.4 9.8 2.8 8.2 5.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF996) PH PF00169.29 KFR07185.1 - 9.7e-08 32.5 0.0 2.7e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 PH domain Baculo_PEP_C PF04513.12 KFR07185.1 - 0.4 10.7 7.1 3.4 7.7 2.2 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glyco_trans_1_2 PF13524.6 KFR07185.1 - 0.49 10.8 3.5 2.6 8.5 0.2 2.7 2 0 0 2 2 2 0 Glycosyl transferases group 1 NAPRTase_N PF17767.1 KFR07185.1 - 2 8.8 13.5 1.2 9.5 3.0 3.5 3 1 1 4 4 4 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain ERM PF00769.19 KFR07185.1 - 5.8 6.7 69.4 0.016 15.0 27.7 2.5 2 1 0 2 2 2 0 Ezrin/radixin/moesin family DUF4659 PF15558.6 KFR07186.1 - 1.2e-127 425.9 129.8 1.4e-127 425.6 129.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4659) Sushi PF00084.20 KFR07187.1 - 2.9e-07 31.0 6.3 4.8e-07 30.3 6.3 1.4 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) RRM_1 PF00076.22 KFR07188.1 - 1.9e-17 62.8 0.0 1.7e-12 46.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFR07188.1 - 0.00038 20.4 0.0 0.00066 19.7 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.6 KFR07188.1 - 0.047 13.3 0.0 0.09 12.4 0.0 1.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4551 PF15087.6 KFR07188.1 - 5.6 5.7 15.2 6.7 5.4 15.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SBF PF01758.16 KFR07189.1 - 6.6e-23 81.4 4.0 6.6e-23 81.4 4.0 3.0 2 1 0 2 2 2 1 Sodium Bile acid symporter family Thyroglobulin_1 PF00086.18 KFR07190.1 - 1.6e-36 123.8 24.5 7.5e-20 70.4 4.8 3.2 3 0 0 3 3 3 2 Thyroglobulin type-1 repeat Thyroglob_assoc PF16597.5 KFR07190.1 - 1.8e-26 92.2 1.0 4.2e-26 91.0 1.0 1.7 1 0 0 1 1 1 1 Thyroglobulin_1 repeat associated disordered domain SPARC_Ca_bdg PF10591.9 KFR07190.1 - 1.4e-10 41.5 0.0 3e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_2 PF07648.15 KFR07190.1 - 1.5e-07 31.4 7.2 1.5e-07 31.4 7.2 4.6 4 1 1 5 5 5 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.6 KFR07190.1 - 0.00013 22.4 0.3 0.00028 21.3 0.1 1.7 2 0 0 2 2 2 1 EF-hand domain pair Kazal_1 PF00050.21 KFR07190.1 - 0.0017 18.3 4.3 0.0017 18.3 4.3 3.4 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain EF-hand_6 PF13405.6 KFR07190.1 - 0.0055 16.5 0.1 0.99 9.5 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KFR07190.1 - 0.016 14.7 0.0 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 KFR07190.1 - 0.043 13.3 0.0 2.7 7.6 0.0 2.4 2 0 0 2 2 2 0 EF hand Defensin_beta PF00711.19 KFR07190.1 - 8.7 6.5 9.4 9.8 6.3 0.5 3.6 3 0 0 3 3 3 0 Beta defensin Calx-beta PF03160.14 KFR07191.1 - 2.2e-62 207.5 8.6 1.1e-30 105.7 0.2 2.8 3 0 0 3 3 3 2 Calx-beta domain Na_Ca_ex PF01699.24 KFR07191.1 - 5.3e-58 195.3 35.7 3.1e-33 114.9 13.2 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Na_Ca_ex_C PF16494.5 KFR07191.1 - 1.7e-54 183.7 5.1 3.9e-54 182.5 5.1 1.6 1 0 0 1 1 1 1 C-terminal extension of sodium/calcium exchanger domain Acyl_transf_3 PF01757.22 KFR07191.1 - 0.69 8.9 26.2 0.28 10.2 12.2 2.5 2 0 0 2 2 2 0 Acyltransferase family Peptidase_C97 PF05903.14 KFR07194.1 - 1.2e-41 142.0 0.0 1.6e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF3670 PF12419.8 KFR07194.1 - 0.21 11.4 0.0 0.61 9.9 0.0 1.7 2 0 0 2 2 2 0 SNF2 Helicase protein PDZ PF00595.24 KFR07195.1 - 2.9e-20 72.4 0.2 4.5e-20 71.8 0.0 1.4 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFR07195.1 - 1.7e-09 37.4 0.0 2.3e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFR07195.1 - 6.1e-08 32.9 0.1 7.3e-08 32.6 0.1 1.1 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 KFR07195.1 - 0.035 14.1 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 Tricorn protease PDZ domain Med6 PF04934.14 KFR07196.1 - 5.1e-44 149.3 0.1 6.9e-44 148.9 0.1 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Peptidase_M15 PF01427.17 KFR07196.1 - 0.0057 16.4 0.1 1.3 8.7 0.0 2.2 2 0 0 2 2 2 2 D-ala-D-ala dipeptidase SAM_decarbox PF01536.16 KFR07196.1 - 0.045 12.7 0.0 0.054 12.5 0.0 1.1 1 0 0 1 1 1 0 Adenosylmethionine decarboxylase Ten1_2 PF15490.6 KFR07196.1 - 0.17 11.6 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit Pkinase PF00069.25 KFR07197.1 - 2.3e-65 220.6 0.0 4.4e-65 219.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR07197.1 - 7e-64 215.6 0.0 9.8e-64 215.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFR07197.1 - 0.0017 17.2 0.0 0.0037 16.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase DUF1476 PF07345.11 KFR07197.1 - 0.021 15.2 0.2 0.056 13.8 0.2 1.7 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta OmpH PF03938.14 KFR07197.1 - 0.051 13.9 3.9 0.097 13.0 3.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3552 PF12072.8 KFR07197.1 - 0.25 10.8 11.6 0.47 9.8 11.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Pecanex_C PF05041.15 KFR07198.1 - 2e-119 397.2 0.0 2.9e-119 396.7 0.0 1.3 1 0 0 1 1 1 1 Pecanex protein (C-terminus) DUF5392 PF17370.2 KFR07198.1 - 0.7 10.0 2.0 2.3 8.3 0.0 2.6 2 1 1 3 3 3 0 Family of unknown function (DUF5392) SPAR_C PF11881.8 KFR07199.1 - 4.4e-84 282.2 12.7 4.4e-84 282.2 12.7 2.9 2 0 0 2 2 1 1 C-terminal domain of SPAR protein Rap_GAP PF02145.15 KFR07199.1 - 5.9e-69 231.4 0.1 1.7e-68 229.8 0.1 1.8 2 0 0 2 2 2 1 Rap/ran-GAP PDZ_6 PF17820.1 KFR07199.1 - 4.7e-06 26.3 0.1 1e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFR07199.1 - 9.3e-05 22.7 0.0 0.0002 21.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain ATG16 PF08614.11 KFR07199.1 - 0.0038 17.5 6.3 0.016 15.4 6.3 2.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4164 PF13747.6 KFR07199.1 - 0.0089 16.3 1.1 0.024 14.9 1.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) Sec34 PF04136.15 KFR07199.1 - 0.013 15.4 0.9 0.035 14.0 0.9 1.7 1 0 0 1 1 1 0 Sec34-like family RasGAP_C PF03836.15 KFR07199.1 - 0.17 12.0 2.1 0.18 11.9 0.4 1.9 2 0 0 2 2 2 0 RasGAP C-terminus YabA PF06156.13 KFR07199.1 - 0.47 11.1 1.9 1.5 9.5 1.9 1.8 1 0 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 KFR07199.1 - 0.48 10.9 10.1 1.4 9.4 10.1 1.8 1 0 0 1 1 1 0 Cell division protein ZapB CASP_C PF08172.12 KFR07199.1 - 1.1 8.5 8.0 0.039 13.3 0.5 2.4 2 0 0 2 2 2 0 CASP C terminal RGS_DHEX PF18148.1 KFR07200.1 - 2.3e-50 168.8 1.8 7.7e-50 167.1 1.8 1.9 1 0 0 1 1 1 1 Regulator of G-protein signalling DHEX domain RGS PF00615.19 KFR07200.1 - 3.5e-34 117.6 0.4 3.5e-34 117.6 0.4 2.3 2 1 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 KFR07200.1 - 4.1e-17 62.0 0.0 1e-16 60.7 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.22 KFR07200.1 - 9.1e-12 44.8 0.1 2.3e-11 43.5 0.1 1.7 1 0 0 1 1 1 1 GGL domain RGS-like PF09128.11 KFR07200.1 - 0.022 14.5 0.3 0.081 12.6 0.0 1.9 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain Requiem_N PF14051.6 KFR07201.1 - 2.3e-37 127.0 0.4 4.9e-37 126.0 0.4 1.6 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. PHD PF00628.29 KFR07201.1 - 4.4e-22 77.7 23.3 3.1e-12 46.2 5.0 3.3 2 1 1 3 3 3 2 PHD-finger PHD_4 PF16866.5 KFR07201.1 - 0.011 15.9 9.3 0.011 15.9 9.3 3.7 2 1 1 3 3 3 0 PHD-finger Lar_restr_allev PF14354.6 KFR07201.1 - 0.016 15.6 1.4 0.016 15.6 1.4 4.0 2 1 1 3 3 3 0 Restriction alleviation protein Lar zf-PHD-like PF15446.6 KFR07201.1 - 0.021 14.5 10.4 0.14 11.7 2.0 2.9 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-C2H2 PF00096.26 KFR07201.1 - 0.027 14.9 1.4 0.027 14.9 1.4 4.8 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR07201.1 - 0.034 15.0 0.8 0.034 15.0 0.8 5.4 5 1 1 6 6 6 0 C2H2-type zinc finger C1_1 PF00130.22 KFR07201.1 - 0.089 12.7 20.9 0.42 10.5 0.4 4.6 3 1 2 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 KFR07201.1 - 0.38 10.7 21.5 0.44 10.5 0.5 4.0 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 KFR07201.1 - 0.91 9.1 20.3 0.075 12.6 1.2 3.9 3 1 1 4 4 4 0 PHD-finger zf-RING_7 PF02591.15 KFR07201.1 - 1.3 9.3 8.7 11 6.3 0.8 3.6 3 1 0 3 3 3 0 C4-type zinc ribbon domain Zf_RING PF16744.5 KFR07201.1 - 1.5 9.0 21.1 12 6.1 5.0 4.8 3 1 1 4 4 4 0 KIAA1045 RING finger WD40 PF00400.32 KFR07202.1 - 0.011 16.6 0.3 9.8 7.2 0.0 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR07202.1 - 0.016 15.5 0.0 0.22 11.9 0.1 2.5 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFR07202.1 - 0.04 12.6 0.0 0.24 10.0 0.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 FYVE PF01363.21 KFR07203.1 - 4.1e-25 87.7 24.1 3.4e-16 59.1 6.1 5.5 5 1 1 6 6 6 2 FYVE zinc finger AIG1 PF04548.16 KFR07203.1 - 0.0022 17.4 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 AIG1 family GBP PF02263.19 KFR07203.1 - 0.0031 16.8 0.0 0.0056 16.0 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Presenilin PF01080.17 KFR07204.1 - 3e-163 543.2 20.0 1.6e-162 540.8 20.0 1.8 1 1 0 1 1 1 1 Presenilin SLATT_4 PF18186.1 KFR07204.1 - 3.5 7.2 6.4 1.2 8.8 0.9 2.5 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 4 PID PF00640.23 KFR07205.1 - 9.1e-35 119.7 0.1 1.5e-34 119.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) NumbF PF06311.12 KFR07205.1 - 2.6e-30 104.8 0.6 2.6e-30 104.8 0.6 3.0 3 0 0 3 3 3 1 NUMB domain PTB PF08416.13 KFR07205.1 - 1.3e-05 25.3 0.0 2.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.6 KFR07205.1 - 3.5e-05 23.8 0.2 6.3e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Cupin_4 PF08007.12 KFR07207.1 - 1.7e-64 218.3 0.0 2.1e-64 218.0 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 KFR07207.1 - 2.3e-06 27.5 0.0 0.00016 21.5 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 KFR07207.1 - 0.0076 15.9 0.0 0.79 9.5 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.22 KFR07207.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Cupin BAAT_C PF08840.11 KFR07208.1 - 1.9e-81 273.1 0.0 2.3e-81 272.8 0.0 1.1 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Bile_Hydr_Trans PF04775.14 KFR07208.1 - 2.5e-39 134.2 0.0 3.4e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region FSH1 PF03959.13 KFR07208.1 - 0.00089 19.0 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KFR07208.1 - 0.0013 18.3 0.0 0.038 13.5 0.0 2.7 2 1 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 KFR07208.1 - 0.0023 17.5 1.2 1.2 8.6 0.2 2.7 2 2 0 2 2 2 2 Dienelactone hydrolase family LRR_4 PF12799.7 KFR07209.1 - 2.2e-14 53.3 11.7 1.9e-05 24.9 6.4 3.5 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFR07209.1 - 9.9e-09 34.9 2.5 9.1e-06 25.3 0.1 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KFR07209.1 - 4.2e-07 29.6 10.2 0.012 15.4 3.9 3.7 3 2 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 KFR07209.1 - 0.59 10.3 4.7 6 7.2 0.3 3.9 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 KFR07209.1 - 3.5 8.5 15.0 47 5.1 0.0 4.8 6 0 0 6 6 6 0 Leucine Rich Repeat ELM2 PF01448.24 KFR07210.1 - 1.9e-09 38.2 2.6 2.9e-09 37.5 0.0 2.5 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-binding PF00249.31 KFR07210.1 - 0.00064 19.9 0.0 0.0015 18.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain ADH_N_2 PF16884.5 KFR07211.1 - 1.3e-26 92.6 0.0 2.7e-26 91.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KFR07211.1 - 5.6e-15 56.6 0.0 1.6e-13 51.8 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFR07211.1 - 8.3e-13 48.5 0.0 1.4e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Orthopox_F14 PF06076.12 KFR07211.1 - 0.0075 16.5 0.1 0.014 15.6 0.1 1.4 1 0 0 1 1 1 1 Orthopoxvirus F14 protein Metallophos PF00149.28 KFR07212.1 - 1.3e-09 38.9 0.0 2.3e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Big_7 PF17957.1 KFR07212.1 - 0.0015 19.2 0.6 0.02 15.7 0.0 2.4 2 0 0 2 2 2 1 Bacterial Ig domain zf-UBR PF02207.20 KFR07213.1 - 2.5e-21 75.6 11.7 2.5e-21 75.6 11.7 3.4 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KFR07213.1 - 2e-19 69.2 0.2 4.9e-19 67.9 0.2 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS DUF2534 PF10749.9 KFR07213.1 - 0.31 11.3 1.4 1.1 9.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2534) Tetraspanin PF00335.20 KFR07214.1 - 4.7e-28 98.5 10.7 6e-28 98.1 10.7 1.1 1 0 0 1 1 1 1 Tetraspanin family Alfin PF12165.8 KFR07214.1 - 0.038 13.6 0.1 2.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Alfin DUF1218 PF06749.12 KFR07214.1 - 0.078 13.5 1.4 4.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) ArfGap PF01412.18 KFR07214.1 - 0.17 11.9 3.9 0.42 10.7 3.9 1.8 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf Pkinase PF00069.25 KFR07215.1 - 1.1e-30 106.9 0.0 2.3e-30 105.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR07215.1 - 4.3e-18 65.5 0.0 7.2e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Codanin-1_C PF15296.6 KFR07216.1 - 1.5e-40 138.0 0.1 3.7e-40 136.7 0.1 1.7 1 0 0 1 1 1 1 Codanin-1 C-terminus START PF01852.19 KFR07217.1 - 1.8e-10 40.6 0.0 3.2e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 START domain Kinesin PF00225.23 KFR07218.1 - 2.9e-100 335.4 0.1 2.9e-100 335.4 0.1 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFR07218.1 - 6e-25 87.9 0.1 1.7e-23 83.2 0.0 2.9 2 0 0 2 2 2 1 Microtubule binding Kinesin_assoc PF16183.5 KFR07218.1 - 6e-07 29.8 11.7 4e-05 23.8 0.5 4.4 2 2 1 3 3 3 2 Kinesin-associated FHA PF00498.26 KFR07218.1 - 4.2e-06 27.0 1.7 1.3e-05 25.5 0.2 2.6 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KFR07218.1 - 0.00039 20.7 1.2 0.0011 19.3 0.0 2.4 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain HAUS2 PF15003.6 KFR07219.1 - 1.7e-41 142.0 4.0 2.1e-41 141.8 4.0 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 LRR_8 PF13855.6 KFR07220.1 - 5.9e-32 109.2 52.6 2.1e-11 43.4 8.1 4.0 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFR07220.1 - 1.5e-20 72.9 28.8 1.8e-06 28.1 3.8 4.7 3 1 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFR07220.1 - 5.5e-09 35.8 8.9 7.5e-06 25.5 1.4 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFR07220.1 - 4.3e-08 32.6 24.5 0.33 11.7 0.3 7.6 6 1 1 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.6 KFR07220.1 - 2.9e-05 23.8 24.7 2.9 8.2 0.1 7.5 7 0 0 7 7 7 4 Leucine Rich repeat RsmF_methylt_CI PF17126.5 KFR07220.1 - 0.0012 18.9 0.3 1.2 9.2 0.1 4.1 2 1 1 4 4 4 1 RsmF rRNA methyltransferase first C-terminal domain SNAP-25 PF00835.19 KFR07221.1 - 2.9e-22 78.7 0.5 5.3e-22 77.9 0.5 1.5 1 0 0 1 1 1 1 SNAP-25 family DUF5089 PF17002.5 KFR07221.1 - 2.5e-06 27.5 1.5 6.9e-06 26.1 1.5 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF5089) V-SNARE_C PF12352.8 KFR07221.1 - 0.0003 21.0 5.1 0.014 15.6 1.2 2.5 2 1 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus DUF16 PF01519.16 KFR07221.1 - 0.027 15.0 1.9 6.4 7.3 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 Sec20 PF03908.13 KFR07221.1 - 0.048 13.6 0.7 0.11 12.4 0.7 1.6 1 0 0 1 1 1 0 Sec20 SOAR PF16533.5 KFR07221.1 - 0.049 13.6 0.5 0.42 10.6 0.1 2.2 2 0 0 2 2 2 0 STIM1 Orai1-activating region DUF1664 PF07889.12 KFR07221.1 - 0.12 12.4 5.0 0.35 10.9 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 KFR07221.1 - 0.75 10.1 2.4 7.4 6.9 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) WD40 PF00400.32 KFR07222.1 - 3.1e-17 62.6 5.1 0.016 16.0 0.1 7.0 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR07222.1 - 1e-06 29.0 2.4 1.8 8.9 0.0 5.1 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain zf-C2H2_aberr PF17017.5 KFR07222.1 - 0.0042 17.2 0.3 0.0097 16.1 0.3 1.6 1 0 0 1 1 1 1 Aberrant zinc-finger PQQ_3 PF13570.6 KFR07222.1 - 0.0059 17.1 2.8 61 4.3 0.0 5.2 6 0 0 6 6 6 0 PQQ-like domain WD40_like PF17005.5 KFR07222.1 - 0.033 13.5 3.0 0.27 10.5 0.2 2.1 2 0 0 2 2 2 0 WD40-like domain FOXP-CC PF16159.5 KFR07222.1 - 0.061 14.0 5.6 0.74 10.5 3.9 3.0 1 1 1 2 2 2 0 FOXP coiled-coil domain Peptidase_C2 PF00648.21 KFR07223.1 - 5e-139 462.4 0.4 7.5e-139 461.8 0.4 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KFR07223.1 - 1.1e-52 178.0 0.0 2.8e-52 176.7 0.0 1.7 1 0 0 1 1 1 1 Calpain large subunit, domain III Calpain_u2 PF16648.5 KFR07223.1 - 2.9e-19 69.3 8.1 6.3e-19 68.2 8.1 1.6 1 0 0 1 1 1 1 Unstructured region on Calpain-3 EF-hand_1 PF00036.32 KFR07223.1 - 1.1e-17 62.1 11.8 2.8e-07 29.6 0.1 6.0 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 KFR07223.1 - 3e-15 54.8 9.0 0.00024 20.8 0.0 5.5 6 0 0 6 6 6 4 EF-hand domain EF-hand_8 PF13833.6 KFR07223.1 - 3.6e-12 45.9 11.8 6.8e-10 38.7 0.6 4.8 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 KFR07223.1 - 4.3e-11 41.8 5.4 0.0014 18.1 0.0 4.6 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 KFR07223.1 - 2.4e-10 40.7 9.5 0.00015 22.1 0.6 4.4 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 KFR07223.1 - 0.035 14.0 3.2 1.1 9.2 0.2 2.8 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Ndufs5 PF10200.9 KFR07223.1 - 0.085 13.1 0.2 1.4 9.2 0.0 2.8 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Glyco_hydro_31 PF01055.26 KFR07224.1 - 3.7e-149 497.7 2.1 5.5e-149 497.1 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KFR07224.1 - 8.1e-18 64.5 0.1 4.3e-17 62.2 0.0 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KFR07224.1 - 0.00016 21.9 0.0 0.00043 20.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) NtCtMGAM_N PF16863.5 KFR07224.1 - 0.00053 20.2 0.0 0.0014 18.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Lung_7-TM_R PF06814.13 KFR07225.1 - 4.1e-78 262.6 24.3 1e-76 258.1 24.3 2.2 1 1 0 1 1 1 1 Lung seven transmembrane receptor SNAD4 PF18750.1 KFR07225.1 - 0.00039 20.5 0.1 0.00087 19.4 0.1 1.5 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 KFR07225.1 - 0.006 16.6 0.2 0.024 14.7 0.2 2.0 2 0 0 2 2 2 1 APOBEC2 NAD2 PF18782.1 KFR07225.1 - 0.017 15.3 0.4 0.067 13.3 0.2 2.1 2 0 0 2 2 2 0 Novel AID APOBEC clade 2 NAD1 PF18778.1 KFR07225.1 - 0.039 14.0 0.6 0.09 12.9 0.1 1.8 2 0 0 2 2 2 0 Novel AID APOBEC clade 1 SPT6_acidic PF14632.6 KFR07225.1 - 0.079 13.5 1.2 0.18 12.4 1.2 1.5 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Vps39_1 PF10366.9 KFR07226.1 - 1.1e-32 112.5 3.1 1.1e-32 112.5 3.1 3.2 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KFR07226.1 - 2.1e-31 108.6 4.8 2.1e-31 108.6 4.8 2.8 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 KFR07226.1 - 8.1e-30 104.4 0.1 1.8e-29 103.2 0.1 1.6 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.20 KFR07226.1 - 8e-12 45.2 11.8 1.1e-06 28.6 1.0 4.2 3 1 0 3 3 3 2 Region in Clathrin and VPS PLA2_B PF01735.18 KFR07227.1 - 4.8e-40 137.4 0.2 2e-33 115.6 0.0 2.9 2 1 0 2 2 2 2 Lysophospholipase catalytic domain cPLA2_C2 PF18695.1 KFR07227.1 - 6.1e-26 90.6 0.5 1.2e-25 89.6 0.5 1.5 1 0 0 1 1 1 1 Cytosolic phospholipases A2 C2-domain C2 PF00168.30 KFR07227.1 - 2.8e-11 43.6 0.0 4.7e-10 39.7 0.0 2.4 2 0 0 2 2 2 1 C2 domain PLA2_B PF01735.18 KFR07228.1 - 2.1e-27 95.7 0.0 2.8e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain cPLA2_C2 PF18695.1 KFR07228.1 - 1.4e-21 76.6 0.0 2.7e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Cytosolic phospholipases A2 C2-domain C2 PF00168.30 KFR07229.1 - 9.2e-16 58.0 0.9 1.5e-15 57.3 0.4 1.6 1 1 1 2 2 2 1 C2 domain PLA2_B PF01735.18 KFR07230.1 - 2.8e-27 95.3 0.0 1.8e-26 92.6 0.0 2.1 1 1 0 1 1 1 1 Lysophospholipase catalytic domain cPLA2_C2 PF18695.1 KFR07230.1 - 1.4e-19 70.1 1.5 5.7e-19 68.1 0.0 2.3 2 1 0 2 2 2 1 Cytosolic phospholipases A2 C2-domain C2 PF00168.30 KFR07230.1 - 5.3e-15 55.6 0.6 1.1e-14 54.6 0.6 1.5 1 0 0 1 1 1 1 C2 domain PLA2_B PF01735.18 KFR07231.1 - 1.3e-31 109.6 0.0 3e-28 98.5 0.0 2.7 2 1 1 3 3 3 2 Lysophospholipase catalytic domain cPLA2_C2 PF18695.1 KFR07231.1 - 1.3e-18 67.0 1.8 7.1e-18 64.6 0.2 2.5 2 0 0 2 2 2 1 Cytosolic phospholipases A2 C2-domain C2 PF00168.30 KFR07231.1 - 9.9e-14 51.5 0.3 2.2e-13 50.4 0.3 1.6 1 0 0 1 1 1 1 C2 domain PLA2_B PF01735.18 KFR07232.1 - 5.3e-35 120.8 0.1 8.1e-32 110.3 0.0 2.3 2 0 0 2 2 2 2 Lysophospholipase catalytic domain cPLA2_C2 PF18695.1 KFR07232.1 - 5.8e-24 84.2 1.8 7.7e-23 80.6 0.2 2.4 2 0 0 2 2 2 1 Cytosolic phospholipases A2 C2-domain C2 PF00168.30 KFR07232.1 - 4.7e-18 65.4 1.6 6e-18 65.0 0.2 1.9 2 0 0 2 2 2 1 C2 domain PLA2_B PF01735.18 KFR07233.1 - 1.6e-27 96.1 0.0 2.2e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain cPLA2_C2 PF18695.1 KFR07233.1 - 1.4e-16 60.5 0.0 3.6e-16 59.1 0.0 1.8 1 1 0 1 1 1 1 Cytosolic phospholipases A2 C2-domain DUF5600 PF18150.1 KFR07234.1 - 1.1e-45 154.5 2.0 2.2e-45 153.6 2.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 KFR07234.1 - 6.2e-16 58.2 0.0 2.8e-15 56.2 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Dynamin_N PF00350.23 KFR07234.1 - 6.7e-06 26.3 0.0 3.3e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 Dynamin family EF-hand_1 PF00036.32 KFR07234.1 - 0.00041 19.7 0.6 0.0017 17.8 0.1 2.3 2 0 0 2 2 2 1 EF hand MMR_HSR1 PF01926.23 KFR07234.1 - 0.0023 18.0 0.0 0.0058 16.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_7 PF13499.6 KFR07234.1 - 0.0088 16.5 0.0 0.064 13.7 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair RcsD_ABL PF16359.5 KFR07234.1 - 0.018 15.1 0.1 0.039 14.1 0.1 1.5 1 0 0 1 1 1 0 RcsD-ABL domain EF-hand_8 PF13833.6 KFR07234.1 - 0.07 13.0 0.7 1.7 8.5 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain pair WD40 PF00400.32 KFR07235.1 - 2.7e-34 116.6 19.3 0.0014 19.5 0.3 12.0 11 0 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR07235.1 - 5.7e-11 42.6 1.2 0.0025 18.1 0.0 6.3 7 0 0 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFR07235.1 - 0.11 11.8 4.7 2.1 7.6 0.1 3.8 4 0 0 4 4 4 0 WD40-like domain Pkinase_Tyr PF07714.17 KFR07238.1 - 1.6e-87 293.1 0.0 2.1e-87 292.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR07238.1 - 7.2e-38 130.4 0.0 1.1e-37 129.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ig_3 PF13927.6 KFR07238.1 - 1.2e-17 64.3 0.3 1.7e-09 38.1 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFR07238.1 - 3.9e-16 58.9 1.1 6.3e-13 48.6 0.1 2.8 2 1 0 2 2 2 2 Immunoglobulin I-set domain fn3 PF00041.21 KFR07238.1 - 1.5e-15 57.3 0.7 1.9e-09 37.7 0.3 2.6 2 0 0 2 2 2 2 Fibronectin type III domain Ig_2 PF13895.6 KFR07238.1 - 1.3e-13 51.1 0.0 2.9e-09 37.1 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFR07238.1 - 7e-12 45.4 0.3 7.5e-09 35.6 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFR07238.1 - 9.7e-06 25.7 0.0 0.0021 18.2 0.0 2.8 1 1 0 1 1 1 1 Immunoglobulin V-set domain Kinase-like PF14531.6 KFR07238.1 - 0.2 10.9 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF4381 PF14316.6 KFR07238.1 - 1.6 9.0 3.9 0.6 10.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) TMEM151 PF14857.6 KFR07239.1 - 3.2e-198 658.9 15.0 3.6e-198 658.8 15.0 1.0 1 0 0 1 1 1 1 TMEM151 family RPAP1_C PF08620.10 KFR07240.1 - 3.2e-27 94.4 1.9 6.6e-27 93.4 0.7 2.2 2 0 0 2 2 2 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KFR07240.1 - 9.6e-17 60.5 4.0 2.6e-16 59.1 4.0 1.8 1 0 0 1 1 1 1 RPAP1-like, N-terminal Pkinase_Tyr PF07714.17 KFR07241.1 - 9.6e-89 297.1 0.0 1.2e-88 296.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR07241.1 - 1.5e-33 116.3 0.0 2.2e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Gly_rich PF12810.7 KFR07241.1 - 3e-21 76.5 24.5 4.9e-21 75.8 24.5 1.2 1 0 0 1 1 1 1 Glycine rich protein FXa_inhibition PF14670.6 KFR07241.1 - 1.2 9.4 9.9 1.1 9.5 7.5 2.3 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site IPK PF03770.16 KFR07242.1 - 1.2e-42 146.1 0.0 2.7e-42 144.9 0.0 1.6 1 1 0 1 1 1 1 Inositol polyphosphate kinase Sulfotransfer_2 PF03567.14 KFR07243.1 - 2.3e-44 152.2 1.9 2.7e-44 152.0 1.9 1.0 1 0 0 1 1 1 1 Sulfotransferase family Pkip-1 PF06878.11 KFR07243.1 - 0.043 13.9 0.8 0.076 13.1 0.1 1.6 2 1 0 2 2 2 0 Pkip-1 protein EF-hand_1 PF00036.32 KFR07243.1 - 0.15 11.7 0.1 0.99 9.1 0.1 2.3 2 0 0 2 2 2 0 EF hand Plus-3 PF03126.18 KFR07245.1 - 1.4e-36 125.3 0.1 1.4e-36 125.3 0.1 2.8 2 0 0 2 2 2 1 Plus-3 domain NUSAP PF16006.5 KFR07246.1 - 3.6e-117 391.4 26.2 3.6e-117 391.4 26.2 2.1 2 0 0 2 2 2 1 Nucleolar and spindle-associated protein EF-hand_11 PF08976.11 KFR07246.1 - 0.038 14.9 0.0 0.1 13.5 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain TRAUB PF08164.12 KFR07246.1 - 0.12 12.9 0.0 0.12 12.9 0.0 4.1 3 2 0 3 3 3 0 Apoptosis-antagonizing transcription factor, C-terminal EF-hand_7 PF13499.6 KFR07247.1 - 8.7e-18 64.5 3.1 3.7e-13 49.7 0.9 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFR07247.1 - 1.7e-16 58.6 1.3 5.9e-07 28.9 0.3 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 KFR07247.1 - 1.7e-16 58.4 2.7 1.9e-06 27.0 0.4 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KFR07247.1 - 1.1e-07 31.6 1.6 3.2e-05 23.7 0.3 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KFR07247.1 - 2.1e-07 30.1 3.7 0.014 14.9 0.2 3.4 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 KFR07247.1 - 3.2e-05 24.2 0.0 0.0014 18.9 0.1 2.4 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region RST PF12174.8 KFR07247.1 - 0.00084 19.2 0.3 0.0039 17.1 0.0 2.2 3 0 0 3 3 3 1 RCD1-SRO-TAF4 (RST) plant domain EF-hand_4 PF12763.7 KFR07247.1 - 0.062 13.3 1.3 2.1 8.3 0.2 2.4 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand SNF2_N PF00176.23 KFR07248.1 - 7.4e-69 232.1 0.6 1.6e-68 231.0 0.6 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 KFR07248.1 - 3.5e-48 163.4 22.9 3.5e-48 163.4 22.9 3.9 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.31 KFR07248.1 - 5e-18 65.5 0.6 2.6e-17 63.2 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFR07248.1 - 2.7e-08 34.0 5.1 5e-06 26.6 0.0 3.8 2 1 1 3 3 3 2 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KFR07248.1 - 1.7e-05 24.1 0.1 1.7e-05 24.1 0.1 3.7 5 0 0 5 5 5 1 Class II histone deacetylase complex subunits 2 and 3 POTRA PF07244.15 KFR07248.1 - 8.7 7.0 6.8 2.8 8.6 0.3 3.1 3 0 0 3 3 3 0 Surface antigen variable number repeat EGF PF00008.27 KFR07249.1 - 6.4e-33 112.7 138.5 5.9e-09 36.1 9.9 9.2 8 1 0 8 8 8 7 EGF-like domain hEGF PF12661.7 KFR07249.1 - 1.1e-23 82.9 104.6 3e-07 30.8 6.5 10.3 9 0 0 9 9 9 7 Human growth factor-like EGF MNNL PF07657.13 KFR07249.1 - 2.8e-17 62.5 0.1 2.8e-17 62.5 0.1 5.4 5 3 1 6 6 6 1 N terminus of Notch ligand EGF_2 PF07974.13 KFR07249.1 - 3.5e-16 59.2 147.8 0.0047 17.3 11.9 9.0 8 1 0 8 8 8 8 EGF-like domain cEGF PF12662.7 KFR07249.1 - 0.00048 20.0 80.8 0.013 15.4 2.4 8.9 8 1 0 8 8 8 5 Complement Clr-like EGF-like EGF_CA PF07645.15 KFR07249.1 - 0.00073 19.7 11.0 0.00073 19.7 11.0 9.7 4 2 4 8 8 8 3 Calcium-binding EGF domain EGF_3 PF12947.7 KFR07249.1 - 0.00078 19.6 7.7 0.00078 19.6 7.7 9.3 6 3 2 8 8 8 4 EGF domain DUF4381 PF14316.6 KFR07249.1 - 0.059 13.6 0.0 0.095 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Ly49 PF08391.10 KFR07249.1 - 0.092 13.1 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Laminin_EGF PF00053.24 KFR07249.1 - 0.18 12.0 119.0 0.79 9.9 8.2 9.1 2 2 6 8 8 8 0 Laminin EGF domain Pep3_Vps18 PF05131.14 KFR07251.1 - 1.7e-41 141.5 0.2 2.6e-40 137.6 0.0 2.4 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KFR07251.1 - 2.8e-11 43.4 20.2 3.4e-09 36.7 4.1 3.0 3 1 0 3 3 2 2 Region in Clathrin and VPS zf-C3HC4_2 PF13923.6 KFR07251.1 - 0.0014 18.4 1.3 0.0014 18.4 1.3 2.9 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KFR07251.1 - 0.0019 17.8 0.1 0.0019 17.8 0.1 2.4 3 0 0 3 3 2 1 Zinc-ribbon, C4HC2 type Vps39_2 PF10367.9 KFR07251.1 - 0.0025 18.2 1.7 0.0047 17.3 0.4 2.2 2 0 0 2 2 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.6 KFR07251.1 - 0.0067 16.4 0.3 0.028 14.4 0.3 2.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFR07251.1 - 0.015 15.3 0.5 0.055 13.5 0.5 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 KFR07251.1 - 0.021 15.1 0.5 0.021 15.1 0.5 2.7 2 0 0 2 2 2 0 Ring finger domain zf-RING_11 PF17123.5 KFR07251.1 - 0.025 14.3 0.9 0.025 14.3 0.9 2.6 2 0 0 2 2 2 0 RING-like zinc finger zf-ANAPC11 PF12861.7 KFR07251.1 - 0.038 14.0 0.2 0.13 12.4 0.2 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF5600 PF18150.1 KFR07251.1 - 0.038 14.6 0.1 0.27 11.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5600) Nup54_57_C PF18570.1 KFR07251.1 - 0.053 13.1 2.3 0.1 12.2 0.6 2.3 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain zf-rbx1 PF12678.7 KFR07251.1 - 0.062 13.6 0.2 0.062 13.6 0.2 2.2 2 0 0 2 2 1 0 RING-H2 zinc finger domain DUF2229 PF09989.9 KFR07251.1 - 0.064 12.9 0.0 0.2 11.3 0.0 1.8 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Taxilin PF09728.9 KFR07251.1 - 0.083 12.1 4.2 0.049 12.8 0.4 2.1 2 0 0 2 2 2 0 Myosin-like coiled-coil protein Dzip-like_N PF13815.6 KFR07251.1 - 0.087 12.8 1.6 7.9 6.5 0.2 2.6 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF1664 PF07889.12 KFR07251.1 - 0.09 12.8 1.4 0.23 11.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) KNOX2 PF03791.13 KFR07251.1 - 0.1 12.1 1.1 0.3 10.6 0.3 2.3 2 0 0 2 2 1 0 KNOX2 domain Exonuc_VII_S PF02609.16 KFR07251.1 - 2.9 8.0 6.8 23 5.1 1.5 3.5 3 0 0 3 3 3 0 Exonuclease VII small subunit XhlA PF10779.9 KFR07251.1 - 5.6 7.3 6.9 0.85 9.9 2.3 2.1 2 0 0 2 2 1 0 Haemolysin XhlA Ras PF00071.22 KFR07252.1 - 2.7e-47 160.4 0.0 3.5e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR07252.1 - 1.7e-22 79.9 0.0 2.7e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR07252.1 - 2.3e-05 23.9 0.0 3.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFR07252.1 - 0.046 13.8 0.0 0.081 13.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SNARE PF05739.19 KFR07252.1 - 0.11 12.5 0.2 0.21 11.6 0.2 1.4 1 0 0 1 1 1 0 SNARE domain AAA_7 PF12775.7 KFR07252.1 - 0.17 11.4 0.1 0.62 9.6 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Kunitz_BPTI PF00014.23 KFR07253.1 - 2.9e-32 110.6 23.2 1.3e-18 66.9 8.7 3.3 4 0 0 4 4 4 2 Kunitz/Bovine pancreatic trypsin inhibitor domain MANEC PF07502.14 KFR07253.1 - 7e-28 96.7 1.6 7e-28 96.7 1.6 3.0 3 1 1 4 4 4 1 MANEC domain Ldl_recept_a PF00057.18 KFR07253.1 - 9.9e-08 32.1 11.6 4.7e-07 29.9 11.6 2.3 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Orf78 PF06024.12 KFR07253.1 - 0.00069 19.9 0.1 0.0017 18.6 0.0 1.6 2 0 0 2 2 2 1 Orf78 (ac78) REJ PF02010.15 KFR07253.1 - 0.017 13.9 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 REJ domain Chordopox_A13L PF05961.11 KFR07253.1 - 0.032 14.4 0.2 0.27 11.5 0.0 2.2 2 0 0 2 2 2 0 Chordopoxvirus A13L protein DUF3377 PF11857.8 KFR07253.1 - 0.054 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) PKD PF00801.20 KFR07253.1 - 0.067 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 PKD domain Y_Y_Y PF07495.13 KFR07253.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Y_Y_Y domain EphA2_TM PF14575.6 KFR07253.1 - 0.16 12.9 0.1 0.48 11.3 0.1 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PP1_inhibitor PF05361.12 KFR07254.1 - 9e-15 54.9 1.7 9.2e-15 54.9 1.7 1.0 1 0 0 1 1 1 1 PKC-activated protein phosphatase-1 inhibitor Cluap1 PF10234.9 KFR07255.1 - 0.012 15.0 0.3 0.012 15.0 0.3 2.3 2 1 0 2 2 2 0 Clusterin-associated protein-1 Cytochrome_CBB3 PF13442.6 KFR07255.1 - 0.27 11.6 0.2 0.27 11.6 0.2 2.2 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III FYVE PF01363.21 KFR07255.1 - 2.9 8.1 26.8 0.079 13.1 12.4 2.5 2 0 0 2 2 2 0 FYVE zinc finger CUB PF00431.20 KFR07256.1 - 1.6e-63 211.9 0.2 7.8e-31 106.7 0.0 2.8 3 0 0 3 3 3 2 CUB domain Astacin PF01400.24 KFR07256.1 - 4.2e-56 189.6 0.0 6.4e-56 189.0 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB_2 PF02408.20 KFR07256.1 - 0.0077 16.0 3.3 0.12 12.1 0.1 2.6 2 0 0 2 2 2 2 CUB-like domain UPF0444 PF15475.6 KFR07257.1 - 1.9e-44 149.8 13.4 2.1e-44 149.7 13.4 1.0 1 0 0 1 1 1 1 Transmembrane protein C12orf23, UPF0444 APC1_C PF18122.1 KFR07258.1 - 0.041 13.8 0.0 0.047 13.6 0.0 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain Sulfotransfer_1 PF00685.27 KFR07259.1 - 1.1e-56 192.3 0.0 1.3e-56 192.0 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFR07259.1 - 1.4e-15 58.2 0.0 1e-10 42.3 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase family TPT PF03151.16 KFR07260.1 - 5.7e-23 81.7 6.9 6.6e-23 81.5 6.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFR07260.1 - 3.3e-08 33.8 26.6 0.0001 22.5 9.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family FAD_binding_7 PF03441.14 KFR07261.1 - 3.3e-78 261.8 0.1 5.3e-78 261.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KFR07261.1 - 2.4e-29 102.4 0.0 6.1e-29 101.1 0.0 1.6 2 0 0 2 2 2 1 DNA photolyase Peripla_BP_6 PF13458.6 KFR07261.1 - 0.013 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein Pex16 PF08610.10 KFR07263.1 - 1.8e-66 224.6 3.9 2e-66 224.4 3.9 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) BESS PF02944.20 KFR07263.1 - 0.13 12.1 0.2 0.31 10.9 0.2 1.6 1 0 0 1 1 1 0 BESS motif PHD PF00628.29 KFR07264.1 - 1.8e-12 46.9 6.6 3.9e-12 45.9 6.6 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KFR07264.1 - 0.0036 17.5 0.1 0.015 15.6 0.1 2.0 1 0 0 1 1 1 1 PHD-like zinc-binding domain C1_1 PF00130.22 KFR07264.1 - 0.005 16.7 2.0 0.005 16.7 2.0 1.8 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) AT_hook PF02178.19 KFR07264.1 - 0.0088 15.8 1.8 0.026 14.4 1.8 1.8 1 0 0 1 1 1 1 AT hook motif PHD_2 PF13831.6 KFR07264.1 - 0.023 14.2 1.0 0.023 14.2 1.0 1.9 2 0 0 2 2 2 0 PHD-finger zf-HC5HC2H_2 PF13832.6 KFR07264.1 - 0.043 14.0 0.1 0.14 12.3 0.1 1.8 1 0 0 1 1 1 0 PHD-zinc-finger like domain Phage_fiber_2 PF03406.13 KFR07264.1 - 0.15 11.6 2.1 0.52 9.9 2.1 2.0 1 0 0 1 1 1 0 Phage tail fibre repeat DUF1664 PF07889.12 KFR07264.1 - 0.19 11.8 11.3 0.03 14.3 4.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-RING_2 PF13639.6 KFR07264.1 - 0.23 11.8 7.8 0.43 11.0 7.8 1.5 1 0 0 1 1 1 0 Ring finger domain Zf_RING PF16744.5 KFR07264.1 - 0.26 11.4 7.0 1.1 9.4 7.0 2.1 1 1 0 1 1 1 0 KIAA1045 RING finger Seryl_tRNA_N PF02403.22 KFR07264.1 - 0.33 11.2 15.4 0.83 9.9 4.5 2.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain C1_2 PF03107.16 KFR07264.1 - 0.47 10.8 4.2 0.18 12.2 1.4 1.7 2 0 0 2 2 1 0 C1 domain Zn_ribbon_17 PF17120.5 KFR07264.1 - 1.1 8.9 5.2 1.1 8.9 3.4 1.8 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 KFR07264.1 - 1.4 9.3 4.6 2.8 8.3 4.6 1.6 1 0 0 1 1 1 0 RING-like domain OmpH PF03938.14 KFR07264.1 - 1.5 9.2 28.7 0.042 14.2 4.8 2.6 3 0 0 3 3 2 0 Outer membrane protein (OmpH-like) Prok-RING_1 PF14446.6 KFR07264.1 - 2.1 8.4 6.7 1.8 8.5 3.0 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 ADK_lid PF05191.14 KFR07264.1 - 5.5 7.1 8.4 1.2 9.2 3.6 2.4 2 1 0 2 2 2 0 Adenylate kinase, active site lid PhnA_Zn_Ribbon PF08274.12 KFR07264.1 - 5.7 7.0 6.0 6.4 6.8 0.2 2.4 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-PHD-like PF15446.6 KFR07264.1 - 6.2 6.4 10.0 0.12 11.9 0.9 2.7 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain DZR PF12773.7 KFR07264.1 - 6.2 6.9 7.2 2e+02 2.1 7.3 2.4 1 1 0 1 1 1 0 Double zinc ribbon Hormone_1 PF00103.20 KFR07264.1 - 7.4 6.2 11.2 0.3 10.8 3.8 2.1 2 0 0 2 2 2 0 Somatotropin hormone family bZIP_1 PF00170.21 KFR07265.1 - 4.4e-16 58.7 14.5 7.6e-16 58.0 14.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFR07265.1 - 8e-09 35.5 9.4 8e-09 35.5 9.4 2.2 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.17 KFR07265.1 - 2.9e-05 24.5 10.1 6.2e-05 23.4 10.1 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Spc29 PF17082.5 KFR07265.1 - 0.0097 15.8 0.3 0.016 15.0 0.3 1.3 1 0 0 1 1 1 1 Spindle Pole Component 29 LMBR1 PF04791.16 KFR07265.1 - 0.019 13.9 0.1 0.025 13.5 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Tcf25 PF04910.14 KFR07265.1 - 0.05 12.7 0.2 0.07 12.2 0.2 1.1 1 0 0 1 1 1 0 Transcriptional repressor TCF25 HAUS-augmin3 PF14932.6 KFR07265.1 - 0.054 13.1 5.5 0.094 12.3 5.5 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4337 PF14235.6 KFR07265.1 - 0.063 13.4 0.7 0.13 12.4 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) TPR_MLP1_2 PF07926.12 KFR07265.1 - 0.076 13.1 11.0 0.13 12.4 11.0 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein JMY PF15871.5 KFR07265.1 - 0.078 12.3 4.8 0.14 11.4 4.8 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein APG6_N PF17675.1 KFR07265.1 - 0.09 13.3 7.7 0.21 12.1 7.7 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 KFR07265.1 - 0.15 12.2 6.7 0.28 11.4 6.7 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ADIP PF11559.8 KFR07265.1 - 0.17 12.0 11.5 0.31 11.1 11.5 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Goodbye PF17109.5 KFR07265.1 - 0.21 12.0 0.2 0.21 12.0 0.2 1.8 2 0 0 2 2 1 0 fungal STAND N-terminal Goodbye domain DUF4404 PF14357.6 KFR07265.1 - 0.46 11.2 2.6 0.67 10.6 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF3552 PF12072.8 KFR07265.1 - 0.68 9.3 9.2 1.1 8.7 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DAGK_acc PF00609.19 KFR07267.1 - 6e-48 163.2 0.0 1.1e-47 162.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KFR07267.1 - 7.1e-29 100.0 0.0 1.7e-28 98.7 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ank_2 PF12796.7 KFR07267.1 - 7.5e-13 48.9 0.1 2.1e-12 47.4 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) C1_1 PF00130.22 KFR07267.1 - 2.2e-12 46.6 26.0 3e-10 39.8 14.0 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Ank_3 PF13606.6 KFR07267.1 - 2e-09 36.9 0.0 0.0006 20.1 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KFR07267.1 - 1.6e-08 34.9 0.0 0.00042 20.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFR07267.1 - 1.5e-07 31.6 0.0 0.0014 18.8 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFR07267.1 - 0.00051 20.4 0.1 0.11 12.9 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat zf-C2H2_4 PF13894.6 KFR07267.1 - 8.9 7.5 9.1 42 5.3 0.6 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger PTN_MK_N PF05196.13 KFR07268.1 - 2.1e-27 95.1 18.4 2.1e-27 95.1 18.4 2.5 2 1 0 2 2 2 1 PTN/MK heparin-binding protein family, N-terminal domain PTN_MK_C PF01091.18 KFR07268.1 - 5.5e-25 87.5 3.5 5.5e-25 87.5 3.5 2.8 2 1 0 2 2 2 1 PTN/MK heparin-binding protein family, C-terminal domain 7tm_1 PF00001.21 KFR07269.1 - 3.6e-75 252.7 6.6 5e-75 252.2 6.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFR07269.1 - 1.4e-08 34.7 9.1 1.4e-08 34.7 9.1 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFR07269.1 - 4.3e-06 26.3 15.9 1.2e-05 24.9 6.6 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFR07269.1 - 0.00023 21.0 8.7 0.00023 21.0 8.7 2.4 2 1 0 2 2 2 1 Olfactory receptor Orf78 PF06024.12 KFR07269.1 - 1.9 8.9 4.9 4.6 7.6 0.0 3.4 3 0 0 3 3 3 0 Orf78 (ac78) ANAPC4_WD40 PF12894.7 KFR07270.1 - 1.2e-05 25.5 0.0 0.099 12.9 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFR07270.1 - 5.2e-05 23.9 10.1 0.00031 21.5 0.5 4.9 7 0 0 7 7 7 1 WD domain, G-beta repeat eIF2A PF08662.11 KFR07270.1 - 0.054 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A CAP_N PF01213.19 KFR07270.1 - 0.14 11.6 6.7 0.39 10.2 6.7 1.7 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 KFR07270.1 - 0.31 11.1 7.5 0.8 9.8 7.5 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DDE_Tnp_4 PF13359.6 KFR07272.1 - 4.6e-37 127.1 0.0 6.3e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFR07272.1 - 1.4e-06 28.1 0.0 6.8e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 KFR07272.1 - 0.00037 20.2 0.1 0.14 11.8 0.0 2.1 1 1 1 2 2 2 2 Transposase DDE domain ATG13 PF10033.9 KFR07273.1 - 3.4e-14 53.1 0.3 7.6e-07 29.1 0.3 3.0 1 1 1 2 2 2 2 Autophagy-related protein 13 RhoGAP PF00620.27 KFR07274.1 - 7.9e-44 149.2 0.2 1.7e-43 148.1 0.2 1.5 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 KFR07274.1 - 4.6e-40 137.0 3.1 4.7e-40 136.9 1.2 1.9 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KFR07274.1 - 1.2e-09 38.0 0.2 2.6e-09 37.0 0.2 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Trypsin PF00089.26 KFR07275.1 - 4.6e-67 226.1 0.0 6.4e-67 225.6 0.0 1.2 1 0 0 1 1 1 1 Trypsin Kringle PF00051.18 KFR07275.1 - 1.4e-43 147.1 12.9 4.6e-23 81.3 3.9 2.6 2 0 0 2 2 2 2 Kringle domain Thrombin_light PF09396.10 KFR07275.1 - 1.3e-24 85.7 3.7 1.7e-24 85.3 2.6 1.8 2 0 0 2 2 2 1 Thrombin light chain Gla PF00594.20 KFR07275.1 - 5.7e-18 64.8 7.6 1.3e-17 63.7 7.6 1.7 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain DUF1986 PF09342.11 KFR07275.1 - 8.5e-06 26.1 0.1 1.8e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) CLASP_N PF12348.8 KFR07276.1 - 1.1e-33 116.7 4.3 7.2e-07 29.0 0.0 5.5 5 0 0 5 5 5 5 CLASP N terminal HEAT PF02985.22 KFR07276.1 - 4.8e-12 45.0 4.0 0.055 13.7 0.0 9.8 10 0 0 10 10 10 3 HEAT repeat Cnd1 PF12717.7 KFR07276.1 - 1.1e-08 35.3 9.6 0.18 11.8 0.0 8.1 7 1 1 8 8 8 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFR07276.1 - 1.2e-08 35.2 0.7 2.4 8.6 0.0 7.8 7 0 0 7 7 7 2 HEAT repeats TAN PF11640.8 KFR07276.1 - 0.023 14.8 9.4 0.48 10.6 0.2 5.5 6 1 0 6 6 6 0 Telomere-length maintenance and DNA damage repair ParcG PF10274.9 KFR07276.1 - 0.057 13.5 2.9 0.38 10.9 0.1 3.6 4 0 0 4 4 4 0 Parkin co-regulated protein Ldl_recept_b PF00058.17 KFR07277.1 - 2.4e-191 620.0 65.2 8.3e-14 51.8 0.3 20.6 20 0 0 20 20 20 20 Low-density lipoprotein receptor repeat class B Ldl_recept_a PF00057.18 KFR07277.1 - 3.1e-90 296.1 171.0 8.1e-13 48.4 16.2 9.1 8 0 0 8 8 8 8 Low-density lipoprotein receptor domain class A FXa_inhibition PF14670.6 KFR07277.1 - 4.1e-46 154.9 115.2 5.5e-12 45.8 6.9 8.6 8 0 0 8 8 6 6 Coagulation Factor Xa inhibitory site SGL PF08450.12 KFR07277.1 - 2e-32 112.7 28.5 3.4e-08 33.4 4.0 11.3 3 3 4 9 9 9 7 SMP-30/Gluconolactonase/LRE-like region DUF5050 PF16472.5 KFR07277.1 - 1.1e-20 74.0 0.0 0.00056 19.2 0.0 5.2 5 1 0 5 5 5 4 Domain of unknown function (DUF5050) cEGF PF12662.7 KFR07277.1 - 1.1e-14 54.0 40.7 1.2e-08 34.7 0.8 7.6 6 0 0 6 6 6 5 Complement Clr-like EGF-like EGF_CA PF07645.15 KFR07277.1 - 3.2e-06 27.2 10.9 3.2e-06 27.2 10.9 11.3 9 2 1 11 11 6 1 Calcium-binding EGF domain Str_synth PF03088.16 KFR07277.1 - 0.0022 18.0 0.0 13 6.0 0.0 5.6 6 0 0 6 6 6 1 Strictosidine synthase EGF_3 PF12947.7 KFR07277.1 - 0.0078 16.4 9.3 0.0078 16.4 9.3 9.9 11 1 0 11 11 7 2 EGF domain SBBP PF06739.11 KFR07277.1 - 0.043 13.8 1.9 10 6.2 0.0 4.7 5 0 0 5 5 5 0 Beta-propeller repeat SL4P PF17618.2 KFR07277.1 - 1.2 9.2 19.7 7.2 6.7 0.1 8.4 10 0 0 10 10 10 0 Uncharacterized Strongylid L4 protein ArfGap PF01412.18 KFR07279.1 - 3e-27 95.0 1.4 7.4e-27 93.7 1.4 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DBINO PF13892.6 KFR07279.1 - 0.39 11.1 7.2 0.12 12.8 4.0 1.7 2 0 0 2 2 2 0 DNA-binding domain WD40 PF00400.32 KFR07280.1 - 2.8e-11 43.8 9.9 0.00013 22.7 0.1 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KFR07280.1 - 0.12 11.1 0.0 0.27 9.9 0.0 1.5 1 0 0 1 1 1 0 Nup133 N terminal like His_Phos_2 PF00328.22 KFR07281.1 - 1.9e-20 73.6 0.0 2.3e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) zf-C4 PF00105.18 KFR07282.1 - 8.4e-28 96.6 15.5 1.4e-27 95.9 15.5 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFR07282.1 - 1.8e-27 96.3 2.0 3.5e-27 95.3 2.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DENN PF02141.21 KFR07283.1 - 2.1e-33 115.8 2.1 5.2e-33 114.6 2.1 1.7 1 1 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KFR07283.1 - 8.9e-19 68.0 0.7 2.8e-18 66.4 0.7 2.0 1 0 0 1 1 1 1 uDENN domain I-set PF07679.16 KFR07284.1 - 4.3e-104 340.8 15.9 6.7e-17 61.3 0.0 9.1 8 1 0 8 8 8 8 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR07284.1 - 5.8e-71 235.1 1.2 6.4e-13 49.1 0.0 8.6 8 0 0 8 8 8 8 Immunoglobulin domain ig PF00047.25 KFR07284.1 - 3e-41 139.5 5.2 4.7e-08 33.1 0.0 8.5 8 0 0 8 8 8 8 Immunoglobulin domain fn3 PF00041.21 KFR07284.1 - 7e-40 135.3 0.0 2.8e-12 46.8 0.0 4.2 3 0 0 3 3 3 3 Fibronectin type III domain Ig_2 PF13895.6 KFR07284.1 - 1.7e-32 111.6 0.3 3.8e-05 23.9 0.0 8.9 7 2 1 8 8 8 7 Immunoglobulin domain THB PF18362.1 KFR07284.1 - 7e-22 76.7 0.0 1.4e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Tri-helix bundle domain V-set PF07686.17 KFR07284.1 - 6.5e-21 74.6 8.5 0.045 13.9 0.0 10.8 7 4 1 8 8 8 6 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFR07284.1 - 9.1e-09 35.3 0.3 0.27 11.3 0.0 6.3 5 1 0 5 5 5 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFR07284.1 - 3.2e-05 24.2 4.4 22 5.5 0.0 6.4 5 1 1 6 6 6 0 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 KFR07284.1 - 0.00042 20.3 1.8 48 4.1 0.0 6.5 7 0 0 7 7 7 0 Izumo-like Immunoglobulin domain PKD_3 PF16820.5 KFR07284.1 - 0.015 15.1 10.8 0.31 10.8 0.1 5.4 6 0 0 6 6 6 0 PKD-like domain Ets PF00178.22 KFR07285.1 - 1.8e-23 82.8 2.9 3.1e-23 82.0 2.9 1.4 1 0 0 1 1 1 1 Ets-domain Zip PF02535.22 KFR07286.1 - 1.3e-55 189.0 10.6 8.4e-55 186.3 10.6 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter ABC2_membrane_3 PF12698.7 KFR07286.1 - 0.92 8.5 6.6 0.053 12.6 0.4 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein Claudin_2 PF13903.6 KFR07287.1 - 9.4e-13 48.4 5.0 1e-12 48.2 5.0 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFR07287.1 - 0.023 14.6 8.3 0.036 13.9 8.3 1.3 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF3961 PF13106.6 KFR07287.1 - 0.14 11.8 1.1 0.27 10.9 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) AAA PF00004.29 KFR07288.1 - 5.8e-42 143.2 0.0 1.2e-41 142.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KFR07288.1 - 5.7e-20 71.0 0.1 1.1e-19 70.1 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KFR07288.1 - 2.5e-10 40.0 1.1 4.1e-10 39.3 0.3 1.8 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 KFR07288.1 - 4.5e-06 26.7 0.1 2e-05 24.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFR07288.1 - 1.5e-05 25.4 0.3 0.0036 17.7 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KFR07288.1 - 4.4e-05 23.3 0.0 0.00013 21.7 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KFR07288.1 - 0.00019 21.6 0.0 0.00062 19.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFR07288.1 - 0.0005 20.4 0.3 0.082 13.2 0.1 2.5 1 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 KFR07288.1 - 0.0029 16.8 0.0 0.0053 15.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 KFR07288.1 - 0.0029 17.8 0.1 0.0064 16.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 KFR07288.1 - 0.0041 16.6 0.1 0.019 14.4 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 KFR07288.1 - 0.0051 16.2 0.1 0.015 14.7 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Prot_ATP_OB_N PF17758.1 KFR07288.1 - 0.0097 15.5 0.0 1 9.1 0.0 2.5 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain IstB_IS21 PF01695.17 KFR07288.1 - 0.021 14.6 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 KFR07288.1 - 0.038 13.7 0.0 0.25 11.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 KFR07288.1 - 0.038 13.7 0.2 0.13 12.0 0.2 2.0 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 KFR07288.1 - 0.055 12.8 0.2 0.18 11.2 0.0 1.9 3 0 0 3 3 3 0 KaiC TIP49 PF06068.13 KFR07288.1 - 0.08 12.1 0.1 0.2 10.8 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_7 PF12775.7 KFR07288.1 - 0.082 12.4 0.0 0.19 11.2 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KFR07288.1 - 0.15 12.5 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 KFR07288.1 - 0.16 11.5 0.9 1.3 8.5 0.2 2.2 1 1 1 2 2 2 0 AAA domain Rapsyn_N PF10579.9 KFR07289.1 - 8.7e-44 147.5 0.2 1e-42 144.1 0.1 2.5 2 0 0 2 2 2 1 Rapsyn N-terminal myristoylation and linker region TPR_1 PF00515.28 KFR07289.1 - 4.2e-21 73.8 12.5 0.00016 21.3 0.1 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 KFR07289.1 - 1.8e-20 73.0 4.8 8.8e-07 29.1 0.0 5.3 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 KFR07289.1 - 5.2e-16 57.4 11.6 0.0044 17.0 0.1 6.7 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFR07289.1 - 3.5e-12 45.5 6.5 0.035 14.3 0.1 6.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFR07289.1 - 5.7e-11 41.6 2.0 0.057 13.5 0.0 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFR07289.1 - 1.8e-08 34.1 2.4 5.5e-07 29.3 0.3 2.8 2 1 1 3 3 3 1 MalT-like TPR region TPR_10 PF13374.6 KFR07289.1 - 1.3e-06 28.0 1.1 0.0013 18.6 0.2 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF3856 PF12968.7 KFR07289.1 - 2.4e-05 24.5 1.9 0.37 10.8 0.0 3.8 3 1 1 4 4 3 2 Domain of Unknown Function (DUF3856) TPR_19 PF14559.6 KFR07289.1 - 0.00013 22.4 0.4 2.5 8.7 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat zf-RING_11 PF17123.5 KFR07289.1 - 0.00026 20.7 0.6 0.00026 20.7 0.6 2.9 3 0 0 3 3 2 1 RING-like zinc finger TPR_11 PF13414.6 KFR07289.1 - 0.00043 19.9 0.4 7.8 6.3 0.0 4.8 5 0 0 5 5 5 0 TPR repeat TPR_16 PF13432.6 KFR07289.1 - 0.00097 19.7 0.6 27 5.5 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFR07289.1 - 0.0013 19.3 2.5 2.7 9.0 0.1 5.1 5 1 1 6 6 5 1 Tetratricopeptide repeat SNAP PF14938.6 KFR07289.1 - 0.0018 17.8 0.5 0.61 9.5 0.1 2.3 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 KFR07289.1 - 0.0028 18.2 5.0 1.7 9.5 0.1 5.2 6 0 0 6 6 5 1 Tetratricopeptide repeat RPN7 PF10602.9 KFR07289.1 - 0.0058 16.3 5.5 1.1 9.0 1.2 3.7 2 1 2 4 4 4 1 26S proteasome subunit RPN7 Fis1_TPR_C PF14853.6 KFR07289.1 - 0.009 16.1 4.4 0.38 10.9 0.0 4.2 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat zf-RING_2 PF13639.6 KFR07289.1 - 0.024 15.0 0.3 0.024 15.0 0.3 3.9 4 0 0 4 4 4 0 Ring finger domain PCYCGC PF13798.6 KFR07289.1 - 0.037 13.9 2.1 0.11 12.4 0.9 2.4 3 0 0 3 3 3 0 Protein of unknown function with PCYCGC motif ANAPC5 PF12862.7 KFR07289.1 - 0.063 13.3 1.2 13 5.9 0.6 3.6 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 5 ANAPC3 PF12895.7 KFR07289.1 - 0.36 11.1 8.4 6.8 7.0 0.7 3.8 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KFR07289.1 - 0.53 10.8 6.2 22 5.7 0.8 4.9 4 1 0 4 4 3 0 Tetratricopeptide repeat RRM_1 PF00076.22 KFR07290.1 - 1.5e-51 172.1 0.0 2.3e-18 65.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 KFR07290.1 - 7.2e-10 38.8 0.0 0.1 12.7 0.0 3.9 3 2 0 3 3 3 3 RNA binding domain RRM_7 PF16367.5 KFR07290.1 - 0.0002 21.4 0.0 0.75 10.0 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif PHM7_cyt PF14703.6 KFR07290.1 - 0.0036 17.5 5.9 4.2 7.6 1.4 4.3 3 2 1 4 4 4 2 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 KFR07290.1 - 0.016 15.2 0.0 0.56 10.3 0.0 2.9 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif AID PF18767.1 KFR07290.1 - 0.073 13.1 0.0 2.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Activation induced deaminase BRAP2 PF07576.12 KFR07290.1 - 0.084 13.1 0.1 4.3 7.6 0.0 2.8 3 0 0 3 3 3 0 BRCA1-associated protein 2 DSPc PF00782.20 KFR07291.1 - 2.8e-19 69.3 0.1 3.1e-19 69.1 0.1 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFR07291.1 - 9.9e-06 25.3 0.8 0.0001 22.0 0.4 1.9 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPn PF14671.6 KFR07291.1 - 0.0019 18.6 0.0 0.0026 18.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half Y_phosphatase2 PF03162.13 KFR07291.1 - 0.004 16.8 0.1 0.0041 16.7 0.1 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFR07291.1 - 0.0042 17.2 0.0 0.0069 16.5 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate BTB PF00651.31 KFR07292.1 - 2.5e-26 92.1 2.3 4.6e-26 91.2 2.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.6 KFR07292.1 - 1e-17 63.7 5.0 5.2e-06 26.5 0.0 5.2 3 2 2 5 5 5 3 Kelch motif BACK PF07707.15 KFR07292.1 - 5.3e-10 39.3 0.7 5.7e-08 32.8 0.1 2.5 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 KFR07292.1 - 3.9e-07 29.8 0.4 0.048 13.6 0.1 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 KFR07292.1 - 2e-06 27.3 1.0 0.026 14.1 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 KFR07292.1 - 0.00045 20.2 0.4 0.1 12.6 0.0 3.4 3 0 0 3 3 3 1 Galactose oxidase, central domain Complex1_30kDa PF00329.19 KFR07293.1 - 1.5e-43 148.3 0.0 2e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit C1q PF00386.21 KFR07294.1 - 1.3e-71 238.7 1.6 2.2e-38 131.3 0.1 2.1 2 0 0 2 2 2 2 C1q domain BclA_C PF18573.1 KFR07294.1 - 1.1e-06 28.6 0.0 0.041 13.8 0.0 2.1 2 0 0 2 2 2 2 BclA C-terminal domain Rhodanese PF00581.20 KFR07294.1 - 0.00066 20.2 0.0 0.65 10.5 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain DUF3531 PF12049.8 KFR07294.1 - 0.043 13.7 0.1 11 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3531) SH3_9 PF14604.6 KFR07295.1 - 7.7e-11 41.7 0.0 1.5e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFR07295.1 - 0.00012 21.6 0.0 0.00024 20.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain NodZ PF05830.11 KFR07295.1 - 0.0084 15.0 0.4 0.017 13.9 0.0 1.6 2 0 0 2 2 2 1 Nodulation protein Z (NodZ) Wtap PF17098.5 KFR07295.1 - 0.076 12.9 0.5 1.3 8.9 0.1 2.3 2 0 0 2 2 2 0 WTAP/Mum2p family SKI PF01202.22 KFR07295.1 - 0.13 12.4 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase Astacin PF01400.24 KFR07297.1 - 1.1e-59 201.3 0.0 1.9e-59 200.5 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB PF00431.20 KFR07297.1 - 6.5e-30 103.7 0.1 2.4e-29 101.9 0.0 2.0 2 0 0 2 2 2 1 CUB domain C2 PF00168.30 KFR07298.1 - 4.1e-23 81.6 0.0 8.7e-14 51.7 0.1 2.3 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 KFR07298.1 - 2.1e-05 24.4 0.1 0.06 13.3 0.0 2.9 2 1 1 3 3 3 2 Phosphoinositide 3-kinase C2 2OG-FeII_Oxy_4 PF13661.6 KFR07298.1 - 0.016 15.9 0.1 0.043 14.5 0.1 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily SET PF00856.28 KFR07299.1 - 6.6e-06 26.6 0.4 3e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 SET domain zf_PR_Knuckle PF18445.1 KFR07299.1 - 9.8e-05 22.1 1.7 0.00023 20.9 1.7 1.6 1 0 0 1 1 1 1 PR zinc knuckle motif GMAP PF06540.11 KFR07391.1 - 3.4e-26 91.1 0.0 4.6e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Galanin message associated peptide (GMAP) Galanin PF01296.18 KFR07391.1 - 1.8e-20 72.6 1.4 2.6e-20 72.1 1.4 1.3 1 0 0 1 1 1 1 Galanin TCR PF03638.15 KFR07392.1 - 2.6e-16 59.6 53.1 4.6e-13 49.2 23.5 3.2 3 0 0 3 3 3 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 KFR07392.1 - 0.039 14.1 38.1 0.26 11.4 10.4 3.5 3 0 0 3 3 3 0 CXC domain of E3 ubiquitin-protein ligase MSL2 Carn_acyltransf PF00755.20 KFR07393.1 - 3.2e-200 666.7 0.0 3.7e-200 666.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CPT_N PF16484.5 KFR07393.1 - 5.8e-28 96.6 0.2 1.2e-27 95.6 0.2 1.6 1 0 0 1 1 1 1 Carnitine O-palmitoyltransferase N-terminus Trypsin PF00089.26 KFR07394.1 - 4.3e-12 46.3 0.0 4.6e-12 46.2 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF4497 PF14924.6 KFR07394.1 - 0.058 13.9 0.0 0.067 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4497) RVT_1 PF00078.27 KFR07395.1 - 0.0041 16.7 0.0 0.011 15.3 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Yae1_N PF09811.9 KFR07396.1 - 3.7e-14 52.1 58.9 1.8e+04 -24.0 58.9 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Ig_3 PF13927.6 KFR07428.1 - 6.5e-16 58.7 0.0 9.3e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFR07428.1 - 7.2e-15 54.8 0.0 1.3e-14 54.0 0.0 1.4 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFR07428.1 - 1.3e-10 41.3 0.0 1.8e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFR07428.1 - 4.5e-10 39.7 0.0 7.1e-10 39.1 0.0 1.3 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFR07428.1 - 4.2e-06 26.9 0.1 0.00031 20.9 0.1 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFR07428.1 - 0.0018 18.3 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.12 KFR07428.1 - 0.045 13.8 0.0 0.1 12.7 0.0 1.6 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family Ig_6 PF18452.1 KFR07428.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain Bcl-2 PF00452.19 KFR07436.1 - 6.7e-19 68.4 0.3 9.2e-19 68.0 0.3 1.2 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family BALF1 PF06861.11 KFR07436.1 - 0.041 13.5 0.0 0.052 13.2 0.0 1.1 1 0 0 1 1 1 0 BALF1 protein Endosulfine PF04667.17 KFR07437.1 - 1e-10 41.6 1.2 1.3e-10 41.3 1.2 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Ntox30 PF15532.6 KFR07437.1 - 0.062 13.7 0.0 0.069 13.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin 30 GPP34 PF05719.11 KFR07438.1 - 8.5e-50 169.6 1.2 9.8e-50 169.4 1.2 1.0 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) HORMA PF02301.18 KFR07439.1 - 1.3e-53 181.7 0.0 2e-53 181.1 0.0 1.3 1 0 0 1 1 1 1 HORMA domain GCN5L1 PF06320.13 KFR07440.1 - 0.092 12.9 1.1 0.26 11.5 0.3 2.1 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) Apelin PF15360.6 KFR07440.1 - 1.4 9.6 6.0 2.2 8.9 2.2 3.2 3 0 0 3 3 3 0 APJ endogenous ligand DUF2756 PF10956.8 KFR07441.1 - 0.071 13.6 3.5 0.26 11.8 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2756) C2 PF00168.30 KFR07442.1 - 8.5e-46 154.5 0.1 2.1e-21 76.1 0.0 2.4 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 KFR07442.1 - 0.00031 20.4 0.0 0.1 12.2 0.0 2.6 2 1 0 2 2 2 2 CEP76 C2 domain PTEN_C2 PF10409.9 KFR07442.1 - 0.016 14.9 0.1 0.032 14.0 0.1 1.5 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein CoatB PF10389.9 KFR07442.1 - 0.36 10.7 4.0 0.75 9.7 4.0 1.5 1 0 0 1 1 1 0 Bacteriophage coat protein B PAH PF02671.21 KFR07443.1 - 4.2e-11 42.8 4.3 1.1e-06 28.6 0.2 3.5 3 0 0 3 3 3 2 Paired amphipathic helix repeat Myb_DNA-bind_6 PF13921.6 KFR07443.1 - 0.00082 19.6 0.1 0.033 14.4 0.1 3.3 2 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFR07443.1 - 0.006 16.7 0.0 0.043 14.0 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain DAP3 PF10236.9 KFR07444.1 - 3.3e-86 289.3 0.0 3.9e-86 289.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 ATPase_2 PF01637.18 KFR07444.1 - 0.011 15.6 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KFR07444.1 - 0.019 14.5 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFR07444.1 - 0.022 15.1 0.0 0.039 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 KFR07444.1 - 0.029 14.4 0.0 0.039 14.0 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.12 KFR07444.1 - 0.048 13.6 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain RUN PF02759.19 KFR07445.1 - 1.3e-17 64.0 0.0 2.9e-17 62.9 0.0 1.6 2 0 0 2 2 2 1 RUN domain SH3_1 PF00018.28 KFR07445.1 - 1.3e-09 37.5 0.0 3e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFR07445.1 - 2e-08 33.8 0.1 8e-08 31.8 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KFR07445.1 - 6e-08 32.4 0.0 1.3e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain polyprenyl_synt PF00348.17 KFR07446.1 - 8e-83 277.4 0.0 9.8e-83 277.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Ion_trans PF00520.31 KFR07447.1 - 9.6e-24 83.9 13.0 1.6e-23 83.2 13.0 1.4 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KFR07447.1 - 2.1e-18 66.1 0.0 4.3e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KFR07447.1 - 6.1e-05 22.9 0.1 0.00021 21.2 0.1 1.9 2 0 0 2 2 2 1 Ion channel Pkinase PF00069.25 KFR07448.1 - 2.3e-51 174.7 0.1 2.9e-51 174.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR07448.1 - 4.3e-21 75.4 0.1 1.5e-20 73.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase SCAMP PF04144.13 KFR07449.1 - 5.4e-65 218.9 18.4 6e-65 218.8 18.4 1.0 1 0 0 1 1 1 1 SCAMP family CD20 PF04103.15 KFR07450.1 - 3.6e-18 66.1 7.8 4.2e-18 65.9 7.8 1.1 1 0 0 1 1 1 1 CD20-like family UPF0139 PF03669.13 KFR07450.1 - 0.89 9.5 4.0 0.76 9.7 0.6 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) Glyco_hydro_30 PF02055.16 KFR07451.1 - 7.9e-162 538.1 0.7 3.6e-161 536.0 0.7 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 KFR07451.1 - 1.8e-08 34.0 0.0 2.7e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30C PF17189.4 KFR07451.1 - 3.3e-08 33.6 0.0 5.4e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain DUF229 PF02995.17 KFR07451.1 - 0.22 10.1 0.0 0.31 9.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Glyco_hydro_30 PF02055.16 KFR07452.1 - 1.7e-149 497.5 0.1 2e-149 497.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 KFR07452.1 - 3.4e-06 26.5 0.0 4.6e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30C PF17189.4 KFR07452.1 - 0.00026 21.2 0.0 0.00044 20.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain DUF229 PF02995.17 KFR07452.1 - 0.064 11.9 0.0 0.089 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Glyco_hydro_30 PF02055.16 KFR07453.1 - 1e-32 113.5 0.1 1.3e-32 113.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30 PF02055.16 KFR07454.1 - 1.1e-81 274.5 0.0 1.3e-81 274.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 KFR07454.1 - 5.5e-07 29.1 0.0 6.3e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 GST_C_6 PF17171.4 KFR07455.1 - 1.8e-22 78.9 0.2 2.2e-22 78.6 0.2 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFR07455.1 - 0.00017 21.6 0.1 0.00021 21.3 0.1 1.3 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TSP_C PF05735.12 KFR07456.1 - 3.4e-70 236.0 0.7 4.6e-70 235.6 0.7 1.2 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.18 KFR07456.1 - 1.3e-61 203.9 132.8 1.4e-14 53.4 10.3 9.6 7 2 1 8 8 8 7 Thrombospondin type 3 repeat COMP PF11598.8 KFR07456.1 - 1.3e-19 70.3 4.3 2.5e-19 69.4 4.3 1.5 1 0 0 1 1 1 1 Cartilage oligomeric matrix protein EGF_CA PF07645.15 KFR07456.1 - 1.1e-12 48.0 21.0 5.9e-08 32.8 1.9 5.7 5 0 0 5 5 5 2 Calcium-binding EGF domain cEGF PF12662.7 KFR07456.1 - 2.4e-08 33.7 31.6 0.0002 21.2 1.8 5.6 4 1 0 4 4 4 2 Complement Clr-like EGF-like EGF_3 PF12947.7 KFR07456.1 - 3.3e-06 27.2 5.2 3.3e-06 27.2 5.2 7.0 4 3 1 5 5 5 3 EGF domain EGF PF00008.27 KFR07456.1 - 0.0005 20.3 5.5 0.0005 20.3 5.5 5.2 4 0 0 4 4 4 2 EGF-like domain Laminin_G_2 PF02210.24 KFR07456.1 - 0.017 15.7 0.0 0.029 14.9 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain TMEM52 PF14979.6 KFR07457.1 - 0.023 14.6 0.3 0.025 14.5 0.3 1.2 1 0 0 1 1 1 0 Transmembrane 52 TMEM132D_C PF15706.5 KFR07457.1 - 0.14 12.0 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Keratin_assoc PF09775.9 KFR07458.1 - 4.9e-56 187.9 5.9 5.6e-56 187.7 5.9 1.0 1 0 0 1 1 1 1 Keratinocyte-associated protein 2 DUF5408 PF17402.2 KFR07458.1 - 0.36 10.7 2.9 0.25 11.3 0.6 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5408) EptA_B_N PF08019.12 KFR07458.1 - 1.6 8.6 7.8 6.1 6.7 2.8 2.0 2 0 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB MtN3_slv PF03083.16 KFR07459.1 - 4.9e-21 74.6 1.0 7.8e-21 73.9 1.0 1.3 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 KFR07459.1 - 0.0017 18.1 1.5 0.0053 16.5 0.1 2.2 2 0 0 2 2 2 1 PQ loop repeat YobH PF13996.6 KFR07459.1 - 0.039 14.0 1.1 0.06 13.4 0.6 1.6 2 0 0 2 2 2 0 YobH-like protein Ephrin PF00812.17 KFR07460.1 - 1.1e-27 96.7 0.8 1.2e-27 96.6 0.8 1.0 1 0 0 1 1 1 1 Ephrin DnaJ PF00226.31 KFR07488.1 - 7.9e-16 57.9 0.3 2.1e-15 56.6 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.22 KFR07488.1 - 1.5e-05 24.7 0.0 3.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFR07488.1 - 0.059 13.0 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BORG_CEP PF14957.6 KFR07489.1 - 5e-08 34.2 1.2 7.4e-08 33.6 1.2 1.5 1 1 0 1 1 1 1 Cdc42 effector GFRP PF06399.13 KFR07490.1 - 3.1e-34 116.7 0.0 3.3e-34 116.6 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I feedback regulatory protein (GFRP) TPR_11 PF13414.6 KFR07491.1 - 0.00057 19.5 0.0 0.033 13.9 0.0 2.8 3 0 0 3 3 3 1 TPR repeat TPR_17 PF13431.6 KFR07491.1 - 0.01 16.2 0.2 0.11 13.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat RPW8 PF05659.11 KFR07491.1 - 0.074 12.7 0.3 0.21 11.3 0.3 1.7 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TPR_2 PF07719.17 KFR07491.1 - 0.37 11.0 3.5 1.4e+02 2.9 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Rad51 PF08423.11 KFR07492.1 - 6.5e-130 431.9 0.0 7.9e-130 431.6 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KFR07492.1 - 2e-11 43.8 0.0 2.9e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KFR07492.1 - 2.2e-09 37.2 0.1 3.4e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 KFR07492.1 - 6e-09 36.4 0.2 2.4e-08 34.5 0.3 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 KFR07492.1 - 2.2e-05 23.9 1.7 0.00013 21.5 1.1 2.4 2 1 0 2 2 2 1 KaiC HHH PF00633.23 KFR07492.1 - 0.017 15.0 0.1 0.039 13.8 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif AAA_22 PF13401.6 KFR07492.1 - 0.018 15.3 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFR07492.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ssDNA_TraI_N PF18272.1 KFR07492.1 - 0.087 12.8 0.2 0.18 11.8 0.2 1.5 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain Knl1_RWD_C PF18210.1 KFR07493.1 - 8.5e-47 157.7 0.1 2e-46 156.5 0.1 1.7 1 0 0 1 1 1 1 Knl1 RWD C-terminal domain Spc7 PF08317.11 KFR07493.1 - 0.00038 19.4 18.3 0.0013 17.7 18.3 1.9 1 1 0 1 1 1 1 Spc7 kinetochore protein SOGA PF11365.8 KFR07493.1 - 0.016 16.3 13.2 0.32 12.2 1.2 3.2 2 1 0 2 2 2 0 Protein SOGA DUF19 PF01579.18 KFR07493.1 - 0.21 11.4 3.6 29 4.4 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF19) AAA_15 PF13175.6 KFR07493.1 - 0.76 9.4 4.9 1.2 8.8 4.7 1.4 1 1 0 1 1 1 0 AAA ATPase domain DUF2508 PF10704.9 KFR07493.1 - 1.4 9.2 15.7 0.36 11.0 3.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) PspB PF06667.12 KFR07493.1 - 2.5 8.2 5.8 1.7 8.8 0.4 2.7 2 0 0 2 2 2 0 Phage shock protein B PMC2NT PF08066.12 KFR07493.1 - 3 8.6 6.4 2.4 8.9 0.6 3.1 2 1 1 3 3 3 0 PMC2NT (NUC016) domain XhlA PF10779.9 KFR07493.1 - 3.2 8.0 8.8 3.6 7.9 0.0 3.4 3 0 0 3 3 3 0 Haemolysin XhlA DUF1664 PF07889.12 KFR07493.1 - 8.6 6.4 6.7 4.1 7.5 0.9 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 KFR07493.1 - 9.1 6.5 21.3 3.4 7.9 5.7 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding PseudoU_synth_2 PF00849.22 KFR07495.1 - 1.4e-30 106.5 0.2 2.4e-30 105.7 0.2 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase PCMT PF01135.19 KFR07496.1 - 4.5e-81 271.6 0.0 5.3e-81 271.4 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KFR07496.1 - 1.3e-06 29.0 0.0 2.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFR07496.1 - 5.3e-06 26.3 0.0 7.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFR07496.1 - 2.2e-05 25.0 0.0 4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFR07496.1 - 0.00024 20.5 0.0 0.00034 20.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GCD14 PF08704.10 KFR07496.1 - 0.00081 19.1 0.0 0.00097 18.9 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit MTS PF05175.14 KFR07496.1 - 0.013 15.0 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 KFR07496.1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KFR07496.1 - 0.084 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 KFR07496.1 - 0.094 13.8 0.0 0.17 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KFR07496.1 - 0.1 12.0 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KFR07496.1 - 0.1 12.5 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CCDC32 PF14989.6 KFR07497.1 - 4.2e-60 202.2 0.2 5.1e-60 201.9 0.2 1.0 1 0 0 1 1 1 1 Coiled-coil domain containing 32 BAH PF01426.18 KFR07498.1 - 6.8e-15 55.0 0.1 2.9e-14 53.0 0.1 1.9 1 1 0 1 1 1 1 BAH domain Acyl-CoA_dh_1 PF00441.24 KFR07499.1 - 4.8e-38 130.7 0.1 7.4e-38 130.1 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFR07499.1 - 1.4e-33 115.9 0.0 2.4e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFR07499.1 - 1.5e-26 92.4 0.0 2.6e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFR07499.1 - 6.5e-10 39.4 0.0 1e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Patched PF02460.18 KFR07500.1 - 0.16 10.0 24.9 0.0042 15.2 2.6 2.5 2 0 0 2 2 2 0 Patched family Sterol-sensing PF12349.8 KFR07500.1 - 2.2 8.1 32.4 0.013 15.3 13.8 2.6 2 0 0 2 2 2 0 Sterol-sensing domain of SREBP cleavage-activation DUF4594 PF15266.6 KFR07501.1 - 2.1e-25 90.1 7.3 2.1e-25 90.1 7.3 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4594) Atg14 PF10186.9 KFR07501.1 - 0.38 9.8 1.9 0.56 9.2 1.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4594 PF15266.6 KFR07502.1 - 2.3e-05 24.8 0.3 2.3e-05 24.8 0.3 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF4594) PI-PLC-X PF00388.19 KFR07503.1 - 8.4e-59 197.3 0.0 2e-58 196.1 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFR07503.1 - 1.7e-39 134.8 1.7 1.7e-39 134.8 1.7 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain PH_14 PF17787.1 KFR07503.1 - 6.2e-39 132.9 0.0 1.1e-38 132.0 0.0 1.5 1 0 0 1 1 1 1 PH domain EF-hand_like PF09279.11 KFR07503.1 - 1.2e-08 35.3 0.0 3.6e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 KFR07503.1 - 3.1e-07 30.6 0.0 6.5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain MMACHC PF16690.5 KFR07503.1 - 0.096 12.3 0.0 0.28 10.8 0.0 1.8 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type C family Pkinase PF00069.25 KFR07504.1 - 3.6e-66 223.2 0.0 4.6e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR07504.1 - 2.4e-44 151.6 0.0 3.3e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KFR07504.1 - 7.3e-16 58.3 0.1 1.6e-15 57.2 0.1 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KFR07504.1 - 5e-06 26.0 0.0 7.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFR07504.1 - 0.00031 19.6 0.0 0.0005 19.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFR07504.1 - 0.16 11.3 0.1 0.26 10.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cadherin PF00028.17 KFR07505.1 - 1.7e-17 63.6 2.1 9.2e-09 35.6 0.1 2.3 2 0 0 2 2 2 2 Cadherin domain Hormone_2 PF00123.20 KFR07506.1 - 2.7e-23 81.5 0.1 3.3e-12 46.1 0.0 2.3 2 0 0 2 2 2 2 Peptide hormone 7tm_1 PF00001.21 KFR07507.1 - 2.1e-54 184.6 2.0 2.4e-54 184.4 2.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR07507.1 - 5.2e-09 35.9 4.8 8.4e-05 22.1 0.0 2.0 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFR07507.1 - 0.0015 18.2 2.6 0.0015 18.2 2.6 1.8 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFR07507.1 - 0.018 14.8 3.4 1.4 8.6 0.2 2.1 2 0 0 2 2 2 0 Olfactory receptor SAND PF01342.21 KFR07508.1 - 2.2e-26 91.3 0.4 6.4e-26 89.9 0.0 2.0 2 0 0 2 2 2 1 SAND domain zf-MYND PF01753.18 KFR07508.1 - 6.4e-10 39.0 15.7 6.4e-10 39.0 15.7 2.0 2 0 0 2 2 2 1 MYND finger Transmemb_17 PF09799.9 KFR07509.1 - 5.7e-30 104.1 10.3 8.7e-30 103.5 10.3 1.3 1 0 0 1 1 1 1 Predicted membrane protein PTB PF08416.13 KFR07510.1 - 3.6e-47 159.8 3.3 6.9e-47 158.9 3.3 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SAM_3 PF18016.1 KFR07510.1 - 6.3e-26 90.0 0.1 1.3e-25 88.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 KFR07510.1 - 1.6e-10 40.4 0.1 4.8e-10 38.9 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFR07510.1 - 4.8e-08 32.7 0.0 1.1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PID PF00640.23 KFR07510.1 - 5.9e-06 26.4 0.8 5.9e-06 26.4 0.8 2.0 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) SH3_2 PF07653.17 KFR07510.1 - 1.3e-05 24.8 0.0 2.6e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFR07510.1 - 0.048 14.0 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain SAM_PNT PF02198.16 KFR07510.1 - 0.092 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain TAL_FSA PF00923.19 KFR07511.1 - 5.2e-98 327.9 0.0 5.7e-98 327.8 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase DJ-1_PfpI PF01965.24 KFR07512.1 - 9.7e-05 22.2 0.0 0.00012 21.9 0.0 1.3 1 1 0 1 1 1 1 DJ-1/PfpI family BTRD1 PF17660.1 KFR07512.1 - 0.086 12.7 0.0 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Bacterial tandem repeat domain 1 ThiJ_like PF17124.5 KFR07512.1 - 0.12 12.1 0.0 0.16 11.6 0.0 1.3 1 1 0 1 1 1 0 ThiJ/PfpI family-like CEND1 PF15677.5 KFR07513.1 - 3.4e-51 173.6 13.9 3.8e-51 173.5 13.9 1.0 1 0 0 1 1 1 1 Cell cycle exit and neuronal differentiation protein 1 Alpha_GJ PF03229.13 KFR07513.1 - 0.0097 16.5 2.2 0.0097 16.5 2.2 1.5 1 1 1 2 2 2 1 Alphavirus glycoprotein J NACHT PF05729.12 KFR07514.1 - 1.8e-34 119.1 0.0 4.7e-34 117.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain NLRC4_HD2 PF17776.1 KFR07514.1 - 3.2e-22 79.4 0.1 1.3e-21 77.5 0.1 2.1 1 0 0 1 1 1 1 NLRC4 helical domain HD2 NOD2_WH PF17779.1 KFR07514.1 - 2e-16 60.0 0.0 5.6e-16 58.6 0.0 1.8 1 0 0 1 1 1 1 NOD2 winged helix domain PYRIN PF02758.16 KFR07514.1 - 3.5e-16 59.1 0.8 1.2e-15 57.3 0.0 2.4 3 0 0 3 3 2 1 PAAD/DAPIN/Pyrin domain AAA_16 PF13191.6 KFR07514.1 - 0.00011 22.7 0.0 0.00039 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KFR07514.1 - 0.00045 20.6 0.0 0.001 19.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KFR07514.1 - 0.0038 17.6 0.0 0.0095 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFR07514.1 - 0.0045 17.3 0.0 0.016 15.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain FISNA PF14484.6 KFR07514.1 - 0.012 15.8 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 0 Fish-specific NACHT associated domain T6SS_VasJ PF16989.5 KFR07514.1 - 0.022 14.2 0.3 0.058 12.9 0.0 1.8 2 0 0 2 2 2 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ AAA_14 PF13173.6 KFR07514.1 - 0.025 14.6 0.0 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KFR07514.1 - 0.025 13.9 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.18 KFR07514.1 - 0.041 13.2 0.1 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.6 KFR07514.1 - 0.087 13.0 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KFR07514.1 - 0.1 12.6 0.0 0.86 9.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KFR07514.1 - 0.13 11.4 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 KFR07514.1 - 0.14 11.8 0.2 0.52 10.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain TPR_2 PF07719.17 KFR07515.1 - 1.6e-07 30.9 2.4 0.00033 20.5 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat PaREP1 PF05942.11 KFR07515.1 - 0.014 15.3 0.4 0.033 14.1 0.0 1.7 2 0 0 2 2 2 0 Archaeal PaREP1/PaREP8 family TPR_11 PF13414.6 KFR07515.1 - 0.015 14.9 8.6 0.64 9.7 1.8 3.2 3 0 0 3 3 3 0 TPR repeat TPR_16 PF13432.6 KFR07515.1 - 0.17 12.5 4.1 2.5 8.8 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFR07515.1 - 0.51 10.3 2.2 3.8 7.5 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFR07515.1 - 0.58 10.1 10.3 0.75 9.7 0.1 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat DDHD PF02862.17 KFR07516.1 - 9e-50 169.9 0.1 7e-47 160.4 0.1 2.2 1 1 0 1 1 1 1 DDHD domain LNS2 PF08235.13 KFR07516.1 - 0.0044 16.5 0.1 0.098 12.1 0.1 2.2 1 1 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Acid_phosphat_B PF03767.14 KFR07516.1 - 0.024 14.2 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) EF-hand_1 PF00036.32 KFR07517.1 - 4.4e-32 107.2 12.2 6e-10 38.0 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KFR07517.1 - 5.9e-26 88.1 4.8 2.4e-08 33.2 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 KFR07517.1 - 4.4e-24 84.7 8.2 8.9e-15 54.9 1.1 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFR07517.1 - 6.4e-23 79.2 9.6 5.4e-09 35.1 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KFR07517.1 - 1.6e-22 79.1 10.4 1.2e-12 47.4 1.0 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 KFR07517.1 - 4.1e-08 33.4 0.3 0.0054 17.0 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KFR07517.1 - 0.00013 22.3 0.2 0.021 15.1 0.0 2.3 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFR07517.1 - 0.00071 19.5 2.1 0.034 14.1 0.2 2.6 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KFR07517.1 - 0.0025 18.0 0.7 0.65 10.2 0.8 3.1 2 1 1 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 KFR07517.1 - 0.0039 15.8 0.0 0.013 14.1 0.0 1.7 1 1 1 2 2 2 1 Family of unknown function (DUF5580) Caleosin PF05042.13 KFR07517.1 - 0.0057 16.6 0.0 0.35 10.8 0.0 2.5 2 1 0 2 2 2 1 Caleosin related protein EFhand_Ca_insen PF08726.10 KFR07517.1 - 0.038 14.1 1.6 0.75 9.9 0.5 2.7 2 2 0 2 2 2 0 Ca2+ insensitive EF hand DUF3349 PF11829.8 KFR07517.1 - 0.052 14.3 0.0 3.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) HMMR_C PF15908.5 KFR07517.1 - 0.13 12.5 0.1 0.28 11.5 0.0 1.6 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal OST-HTH PF12872.7 KFR07517.1 - 0.13 12.1 0.0 3.2 7.7 0.0 2.4 2 0 0 2 2 2 0 OST-HTH/LOTUS domain NADH_4Fe-4S PF10589.9 KFR07518.1 - 4.3e-31 106.8 0.3 1.4e-30 105.2 0.0 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Complex1_51K PF01512.17 KFR07518.1 - 9.4e-14 51.5 0.0 2.4e-13 50.2 0.0 1.7 2 0 0 2 2 2 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit SLBB PF10531.9 KFR07518.1 - 1.3e-07 31.4 0.0 2.3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 SLBB domain Mito_carr PF00153.27 KFR07520.1 - 4.2e-09 36.2 0.0 4e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein WW PF00397.26 KFR07521.1 - 1.9e-19 69.4 19.6 3.2e-10 39.9 4.1 2.4 2 0 0 2 2 2 2 WW domain ASD2 PF08687.11 KFR07521.1 - 0.031 13.8 0.6 0.031 13.8 0.6 2.3 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Acyl-thio_N PF12590.8 KFR07521.1 - 0.079 13.5 0.5 0.079 13.5 0.5 2.2 2 0 0 2 2 2 0 Acyl-ATP thioesterase Glyco_hydro_18 PF00704.28 KFR07521.1 - 0.17 11.6 1.0 0.35 10.6 0.2 1.8 2 0 0 2 2 2 0 Glycosyl hydrolases family 18 Glyco_hyd_101C PF17451.2 KFR07521.1 - 0.35 11.2 8.1 0.5 10.7 1.9 2.6 2 1 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Nup160 PF11715.8 KFR07522.1 - 2.1e-102 343.5 0.0 3.1e-102 343.0 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 RhoGEF PF00621.20 KFR07523.1 - 4e-27 95.6 0.0 1.6e-13 51.3 0.0 2.0 2 0 0 2 2 2 2 RhoGEF domain Churchill PF06573.11 KFR07524.1 - 1.7e-26 92.7 0.2 1.8e-26 92.7 0.2 1.0 1 0 0 1 1 1 1 Churchill protein zf-CHY PF05495.12 KFR07524.1 - 0.039 14.4 0.4 0.048 14.2 0.4 1.1 1 0 0 1 1 1 0 CHY zinc finger TF_Zn_Ribbon PF08271.12 KFR07524.1 - 0.052 13.1 2.4 0.15 11.6 2.4 1.7 1 1 0 1 1 1 0 TFIIB zinc-binding GSHPx PF00255.19 KFR07525.1 - 7.9e-22 76.9 0.3 9.9e-22 76.6 0.3 1.1 1 0 0 1 1 1 1 Glutathione peroxidase UNC-93 PF05978.16 KFR07526.1 - 5.8e-06 26.1 4.0 5.8e-06 26.1 4.0 2.7 3 0 0 3 3 3 2 Ion channel regulatory protein UNC-93 Aldedh PF00171.22 KFR07527.1 - 2.8e-84 283.3 0.0 3.6e-84 282.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TPK_catalytic PF04263.16 KFR07530.1 - 2.1e-39 134.3 0.0 2.3e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain Trypsin_2 PF13365.6 KFR07531.1 - 5e-32 111.9 0.1 7.1e-32 111.4 0.1 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KFR07531.1 - 2e-16 60.5 0.0 2.9e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 KFR07531.1 - 5.8e-13 48.5 0.2 8.3e-12 44.8 0.1 2.3 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 KFR07531.1 - 5.2e-10 39.5 0.2 1.6e-09 38.0 0.2 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFR07531.1 - 5.9e-10 39.3 0.3 2.1e-09 37.6 0.3 2.0 1 0 0 1 1 1 1 PDZ domain Peptidase_S46 PF10459.9 KFR07531.1 - 1.2e-06 27.6 0.7 0.027 13.2 0.0 2.2 2 0 0 2 2 2 2 Peptidase S46 Peptidase_S32 PF05579.13 KFR07531.1 - 2e-05 23.9 0.1 0.088 12.0 0.0 2.1 2 0 0 2 2 2 2 Equine arteritis virus serine endopeptidase S32 DUF150_C PF17384.2 KFR07531.1 - 0.0037 17.4 0.8 0.58 10.3 0.2 2.6 2 0 0 2 2 2 1 RimP C-terminal SH3 domain LSM PF01423.22 KFR07531.1 - 0.0057 16.3 0.5 0.014 15.1 0.1 1.8 2 0 0 2 2 2 1 LSM domain GRASP55_65 PF04495.14 KFR07531.1 - 0.019 15.3 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain ROF PF07073.12 KFR07531.1 - 0.2 11.9 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 Modulator of Rho-dependent transcription termination (ROF) PH PF00169.29 KFR07532.1 - 2e-32 111.8 0.2 5.6e-19 68.6 0.1 2.3 2 0 0 2 2 2 2 PH domain PH_8 PF15409.6 KFR07532.1 - 3.3e-12 46.5 0.1 2.1e-05 24.7 0.0 2.8 2 1 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 KFR07532.1 - 1.3e-08 35.2 1.7 3.5e-05 24.2 0.6 3.7 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 KFR07532.1 - 1.3e-07 32.0 0.3 0.024 15.0 0.1 2.7 2 1 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.7 KFR07532.1 - 1.5e-06 28.3 0.0 0.0024 18.0 0.0 2.4 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology PH_3 PF14593.6 KFR07532.1 - 4.3e-05 23.6 0.9 0.0099 16.0 0.2 2.8 2 2 0 2 2 2 1 PH domain PH_6 PF15406.6 KFR07532.1 - 0.0066 16.7 0.5 5.4 7.3 0.0 3.3 4 0 0 4 4 4 2 Pleckstrin homology domain PH_13 PF16652.5 KFR07532.1 - 0.014 15.2 0.1 2 8.2 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Nse4_C PF08743.10 KFR07534.1 - 6.2e-24 84.1 0.2 1.3e-23 83.1 0.0 1.6 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KFR07534.1 - 1.9e-15 56.7 1.3 4.2e-15 55.6 1.3 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Plant_tran PF04827.14 KFR07534.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Plant transposon protein ATE_C PF04377.15 KFR07535.1 - 1.9e-52 177.4 0.3 1.5e-51 174.5 0.2 2.3 2 1 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KFR07535.1 - 1.7e-13 50.8 4.7 4.4e-13 49.4 4.7 1.8 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus DUF676 PF05057.14 KFR07548.1 - 1.3e-57 194.8 0.0 2.2e-57 194.1 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3657 PF12394.8 KFR07548.1 - 1.3e-18 67.2 3.1 3.8e-18 65.8 1.1 2.7 2 0 0 2 2 2 1 Protein FAM135 Palm_thioest PF02089.15 KFR07548.1 - 1.2e-07 31.8 0.0 3e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 KFR07548.1 - 1.2e-05 25.1 0.0 2.3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 KFR07548.1 - 0.0069 15.6 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Il13Ra_Ig PF18001.1 KFR07548.1 - 1.1 9.4 5.0 7.2 6.8 0.0 3.8 4 0 0 4 4 4 0 Interleukin-13 receptor subunit alpha Ig-like domain Collagen PF01391.18 KFR07550.1 - 2.1e-161 523.8 638.0 4.2e-09 36.0 29.6 20.7 4 4 15 19 19 19 17 Collagen triple helix repeat (20 copies) VWA PF00092.28 KFR07550.1 - 3e-48 164.4 0.1 4.4e-48 163.8 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFR07550.1 - 2.7e-17 63.3 0.0 4.1e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Laminin_G_3 PF13385.6 KFR07550.1 - 0.037 14.2 0.0 0.059 13.5 0.0 1.2 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Ion_trans_2 PF07885.16 KFR07553.1 - 9.2e-38 128.1 16.8 1.8e-18 66.3 8.7 2.9 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KFR07553.1 - 1.5e-07 30.9 3.9 0.019 14.2 0.0 2.2 1 1 0 2 2 2 2 Ion transport protein CLTH PF10607.9 KFR07553.1 - 0.08 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain IRK PF01007.20 KFR07553.1 - 0.19 11.5 4.2 0.31 10.9 0.0 2.6 2 1 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain TRAPPC9-Trs120 PF08626.11 KFR07554.1 - 2e-46 158.0 0.6 2e-20 71.9 0.1 6.6 4 2 1 5 5 5 4 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Vps23_core PF09454.10 KFR07554.1 - 0.05 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Vps23 core domain Sipho_Gp157 PF05565.11 KFR07555.1 - 0.15 12.0 0.0 0.17 11.9 0.0 1.0 1 0 0 1 1 1 0 Siphovirus Gp157 CBFD_NFYB_HMF PF00808.23 KFR07556.1 - 2e-11 44.0 0.0 3.2e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone NOA36 PF06524.12 KFR07556.1 - 0.057 12.7 1.3 0.063 12.6 1.3 1.1 1 0 0 1 1 1 0 NOA36 protein Histone PF00125.24 KFR07556.1 - 0.13 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Pkinase_Tyr PF07714.17 KFR07557.1 - 1.8e-93 312.6 0.0 2.8e-93 311.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Focal_AT PF03623.13 KFR07557.1 - 2.9e-56 189.1 3.0 7.2e-56 187.8 3.0 1.7 1 0 0 1 1 1 1 Focal adhesion targeting region Pkinase PF00069.25 KFR07557.1 - 6.4e-46 156.9 0.0 1.6e-45 155.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain FERM_N_2 PF18038.1 KFR07557.1 - 6.7e-44 148.7 0.2 2e-43 147.2 0.2 1.9 1 0 0 1 1 1 1 FERM N-terminal domain FERM_M PF00373.18 KFR07557.1 - 1.8e-11 44.5 0.1 1.8e-11 44.5 0.1 2.4 3 0 0 3 3 3 1 FERM central domain Haspin_kinase PF12330.8 KFR07557.1 - 0.0013 17.7 0.0 0.0025 16.8 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFR07557.1 - 0.0082 15.5 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FERM_F2 PF18377.1 KFR07557.1 - 0.019 14.9 0.3 0.052 13.5 0.3 1.8 1 0 0 1 1 1 0 FERM F2 acyl-CoA binding protein-like domain uDENN PF03456.18 KFR07560.1 - 3.6e-06 27.6 0.0 8.3e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 uDENN domain DENN PF02141.21 KFR07560.1 - 0.085 12.8 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 DENN (AEX-3) domain dDENN PF03455.19 KFR07561.1 - 3.5e-06 26.9 0.5 1e-05 25.4 0.5 1.8 1 0 0 1 1 1 1 dDENN domain bPH_3 PF14470.6 KFR07561.1 - 0.069 13.5 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 Bacterial PH domain MFS_1 PF07690.16 KFR07562.1 - 6.2e-17 61.5 16.7 6.9e-10 38.4 3.9 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 KFR07562.1 - 1.2e-08 34.0 1.0 1.2e-08 34.0 1.0 2.5 2 1 0 2 2 2 1 MFS/sugar transport protein OATP PF03137.20 KFR07562.1 - 0.0059 15.0 3.7 0.21 9.9 0.1 2.9 4 0 0 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family 7tm_1 PF00001.21 KFR07563.1 - 5e-30 104.7 34.7 8.2e-30 104.0 34.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF5412 PF17428.2 KFR07563.1 - 0.3 10.9 0.1 0.3 10.9 0.1 3.4 2 1 1 3 3 3 0 Family of unknown function (DUF5412) PIRT PF15099.6 KFR07563.1 - 4.9 6.8 7.3 0.16 11.5 0.6 2.0 2 1 0 2 2 2 0 Phosphoinositide-interacting protein family DSPc PF00782.20 KFR07564.1 - 1.8e-08 34.3 0.0 2.4e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFR07564.1 - 4.2e-07 29.8 0.0 6.7e-07 29.1 0.0 1.3 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Syntaxin_2 PF14523.6 KFR07565.1 - 8.1e-23 80.7 9.8 8.1e-23 80.7 9.8 2.2 2 0 0 2 2 2 1 Syntaxin-like protein Syntaxin PF00804.25 KFR07565.1 - 6.7e-08 32.5 16.0 2.4e-06 27.4 10.8 2.7 1 1 1 2 2 2 2 Syntaxin MCPsignal PF00015.21 KFR07565.1 - 0.056 13.2 11.1 1.2 9.0 1.1 2.6 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Cauli_AT PF03233.13 KFR07565.1 - 0.083 12.8 6.6 0.13 12.2 0.2 2.3 1 1 0 2 2 2 0 Aphid transmission protein DUF1664 PF07889.12 KFR07565.1 - 0.084 12.9 11.7 3.1 7.8 1.9 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 KFR07565.1 - 0.12 12.6 12.1 2.6 8.3 0.6 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FUSC PF04632.12 KFR07565.1 - 0.16 10.4 3.1 0.27 9.7 1.2 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family HsbA PF12296.8 KFR07565.1 - 0.18 12.2 5.0 3.1 8.2 1.0 3.0 3 0 0 3 3 3 0 Hydrophobic surface binding protein A Fib_alpha PF08702.10 KFR07565.1 - 0.63 10.2 12.6 0.5 10.5 6.2 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 KFR07565.1 - 0.8 8.9 6.4 1.6 7.9 2.4 2.1 2 0 0 2 2 2 0 TMPIT-like protein DHR10 PF18595.1 KFR07565.1 - 0.93 9.6 17.5 0.24 11.5 7.7 2.5 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain DUF3037 PF11236.8 KFR07565.1 - 0.96 9.9 3.3 1 9.8 0.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3037) CENP-H PF05837.12 KFR07565.1 - 1 9.8 13.1 0.82 10.1 5.4 2.5 2 1 0 2 2 2 0 Centromere protein H (CENP-H) LMBR1 PF04791.16 KFR07565.1 - 1.9 7.3 4.1 2.2 7.1 4.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Noelin-1 PF12308.8 KFR07565.1 - 1.9 8.5 7.5 0.31 11.1 0.5 2.5 2 1 0 2 2 2 0 Neurogenesis glycoprotein DASH_Dad1 PF08649.10 KFR07565.1 - 2.2 8.5 7.4 4.8 7.5 0.4 2.8 3 0 0 3 3 3 0 DASH complex subunit Dad1 MCU PF04678.13 KFR07565.1 - 6.1 6.9 5.7 3.6 7.7 1.2 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF4446 PF14584.6 KFR07565.1 - 7.1 6.6 7.9 3.2 7.7 1.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) Sec34 PF04136.15 KFR07565.1 - 7.8 6.4 10.1 0.78 9.6 2.0 2.6 2 1 1 3 3 3 0 Sec34-like family 7tm_2 PF00002.24 KFR07566.1 - 6.5e-62 209.0 17.5 9e-62 208.5 17.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) TSP_1 PF00090.19 KFR07566.1 - 1.1e-48 163.2 95.2 1.4e-13 50.9 7.2 6.9 7 0 0 7 7 7 5 Thrombospondin type 1 domain GAIN PF16489.5 KFR07566.1 - 1.1e-39 136.0 0.3 2.5e-39 134.9 0.3 1.6 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain GPS PF01825.21 KFR07566.1 - 8.9e-10 39.0 0.1 8.9e-10 39.0 0.1 3.1 3 0 0 3 3 3 1 GPCR proteolysis site, GPS, motif Arc_C PF18162.1 KFR07568.1 - 7e-47 157.2 1.2 1.9e-46 155.8 1.2 1.8 1 0 0 1 1 1 1 Arc C-lobe Retrotrans_gag PF03732.17 KFR07568.1 - 0.001 19.3 2.1 0.0021 18.3 0.5 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein DUF2120 PF09893.9 KFR07568.1 - 0.0062 16.6 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2120) DUF842 PF05811.13 KFR07568.1 - 0.0091 15.7 0.3 0.043 13.5 0.3 2.0 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF842) THOC7 PF05615.13 KFR07568.1 - 0.021 15.1 0.4 0.038 14.3 0.4 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 KxDL PF10241.9 KFR07568.1 - 0.028 14.7 1.2 6.3 7.2 0.1 2.9 4 0 0 4 4 4 0 Uncharacterized conserved protein FH2 PF02181.23 KFR07568.1 - 0.034 13.3 0.5 0.064 12.4 0.5 1.4 1 0 0 1 1 1 0 Formin Homology 2 Domain SYCE1 PF15233.6 KFR07568.1 - 0.15 12.1 5.3 0.59 10.2 0.2 2.7 2 1 0 2 2 2 0 Synaptonemal complex central element protein 1 ThiD2 PF17792.1 KFR07568.1 - 0.18 12.3 1.1 0.37 11.3 1.1 1.5 1 0 0 1 1 1 0 ThiD2 family DDE_Tnp_ISL3 PF01610.17 KFR07568.1 - 0.39 10.4 6.0 9 5.9 2.4 2.7 3 0 0 3 3 3 0 Transposase Toxin_TOLIP PF00087.21 KFR07569.1 - 0.00084 19.5 15.4 0.0011 19.2 15.4 1.2 1 0 0 1 1 1 1 Snake toxin and toxin-like protein RVT_1 PF00078.27 KFR07570.1 - 0.005 16.4 0.0 0.0081 15.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Toxin_TOLIP PF00087.21 KFR07571.1 - 0.00023 21.3 12.7 0.00029 21.0 12.7 1.1 1 0 0 1 1 1 1 Snake toxin and toxin-like protein UPAR_LY6 PF00021.21 KFR07571.1 - 0.00058 20.5 11.9 0.00076 20.1 11.9 1.2 1 0 0 1 1 1 1 u-PAR/Ly-6 domain UPAR_LY6_2 PF16975.5 KFR07571.1 - 0.049 13.8 10.0 0.075 13.2 10.0 1.3 1 1 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 UPAR_LY6 PF00021.21 KFR07572.1 - 5.8e-07 30.1 13.2 7.8e-07 29.7 13.2 1.2 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Toxin_TOLIP PF00087.21 KFR07572.1 - 0.00012 22.2 13.1 0.00019 21.6 13.1 1.3 1 0 0 1 1 1 1 Snake toxin and toxin-like protein BAMBI PF06211.12 KFR07572.1 - 1.7 8.9 8.9 3.1 8.1 8.9 1.5 1 1 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain UPAR_LY6 PF00021.21 KFR07573.1 - 5e-16 59.2 11.2 6.1e-16 58.9 11.2 1.1 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Toxin_TOLIP PF00087.21 KFR07573.1 - 3.9e-10 39.8 10.0 4.7e-10 39.6 10.0 1.1 1 0 0 1 1 1 1 Snake toxin and toxin-like protein UPAR_LY6_2 PF16975.5 KFR07573.1 - 0.036 14.3 7.8 0.056 13.6 7.8 1.4 1 1 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 Toxin_TOLIP PF00087.21 KFR07574.1 - 9.9e-13 48.1 15.8 1.3e-12 47.8 15.8 1.2 1 0 0 1 1 1 1 Snake toxin and toxin-like protein UPAR_LY6 PF00021.21 KFR07574.1 - 5.3e-11 43.1 16.1 6.6e-11 42.8 16.1 1.1 1 0 0 1 1 1 1 u-PAR/Ly-6 domain UPAR_LY6_2 PF16975.5 KFR07574.1 - 4.6e-05 23.6 14.1 0.00011 22.3 14.1 1.6 1 1 0 1 1 1 1 Ly6/PLAUR domain-containing protein 6, Lypd6 Toxin_TOLIP PF00087.21 KFR07575.1 - 5.5e-11 42.6 17.5 7.3e-11 42.2 17.5 1.2 1 0 0 1 1 1 1 Snake toxin and toxin-like protein UPAR_LY6 PF00021.21 KFR07575.1 - 3.3e-09 37.3 17.0 4e-09 37.0 17.0 1.1 1 0 0 1 1 1 1 u-PAR/Ly-6 domain UPAR_LY6 PF00021.21 KFR07576.1 - 3.5e-07 30.8 14.5 9.1e-07 29.5 14.5 1.6 1 1 0 1 1 1 1 u-PAR/Ly-6 domain Toxin_TOLIP PF00087.21 KFR07576.1 - 1.3e-05 25.3 21.7 3.2e-05 24.1 21.0 2.0 1 1 0 1 1 1 1 Snake toxin and toxin-like protein Topoisom_I PF01028.20 KFR07577.1 - 1.7e-102 341.6 8.0 1.7e-102 341.6 8.0 2.4 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KFR07577.1 - 2.2e-100 334.5 4.4 2.2e-100 334.5 4.4 4.0 4 1 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KFR07577.1 - 8.1e-34 115.4 0.4 8.1e-34 115.4 0.4 2.6 2 0 0 2 2 2 1 C-terminal topoisomerase domain Allexi_40kDa PF05549.11 KFR07577.1 - 2 7.9 6.0 4.2 6.8 2.7 2.5 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF2229 PF09989.9 KFR07577.1 - 5.3 6.6 10.1 0.81 9.3 3.4 2.5 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) AAA_27 PF13514.6 KFR07577.1 - 9.6 5.7 11.4 0.11 12.1 2.3 2.4 3 0 0 3 3 3 0 AAA domain BRO1 PF03097.18 KFR07578.1 - 6.1e-96 321.6 0.3 9.3e-96 321.0 0.3 1.2 1 0 0 1 1 1 1 BRO1-like domain HR1 PF02185.16 KFR07578.1 - 2e-20 72.6 4.8 5.5e-20 71.3 4.8 1.8 1 0 0 1 1 1 1 Hr1 repeat PDZ PF00595.24 KFR07578.1 - 1e-13 51.4 0.0 1.9e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFR07578.1 - 1.7e-13 50.2 0.0 3.5e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFR07578.1 - 2.9e-06 27.5 0.0 8.7e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 PDZ domain FAM83 PF07894.12 KFR07578.1 - 0.0018 17.9 0.4 0.004 16.7 0.0 1.8 2 1 0 2 2 2 1 FAM83 A-H Tricorn_PDZ PF14685.6 KFR07578.1 - 0.028 14.4 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain Uds1 PF15456.6 KFR07578.1 - 0.078 13.2 4.3 0.2 11.8 4.3 1.6 1 0 0 1 1 1 0 Up-regulated During Septation UCH PF00443.29 KFR07580.1 - 1e-05 25.2 0.6 6.4e-05 22.6 0.6 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase NAPRTase_C PF17956.1 KFR07581.1 - 3.4e-29 101.5 0.0 5.6e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase_N PF17767.1 KFR07581.1 - 3.6e-10 40.3 0.0 7e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase PF04095.16 KFR07581.1 - 0.0011 18.6 0.0 0.37 10.3 0.0 2.3 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family EF1_GNE PF00736.19 KFR07582.1 - 2.2e-37 127.1 1.1 4.6e-37 126.1 1.1 1.6 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KFR07582.1 - 1.1e-12 48.1 8.4 1.1e-12 48.1 8.4 2.2 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region Lzipper-MIP1 PF14389.6 KFR07582.1 - 0.0038 17.5 0.2 1.1 9.6 0.0 2.9 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 JIP_LZII PF16471.5 KFR07582.1 - 0.025 14.7 0.9 0.059 13.5 0.9 1.6 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II TSC22 PF01166.18 KFR07582.1 - 0.028 14.7 0.3 0.087 13.1 0.2 1.9 1 1 0 1 1 1 0 TSC-22/dip/bun family WD40_alt PF14077.6 KFR07582.1 - 0.15 12.0 0.1 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 Alternative WD40 repeat motif Striatin PF08232.12 KFR07582.1 - 0.17 12.5 5.9 0.036 14.7 1.8 1.9 2 0 0 2 2 2 0 Striatin family CCD48 PF15799.5 KFR07582.1 - 0.84 7.9 7.0 0.084 11.2 0.5 1.9 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 48 DDE_1 PF03184.19 KFR07583.1 - 1.2e-18 67.4 0.0 1.3e-17 64.0 0.0 2.3 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFR07583.1 - 1.2e-17 63.6 0.4 2.5e-17 62.7 0.4 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFR07583.1 - 2.2e-08 33.6 0.0 3.8e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 KFR07583.1 - 2.5e-05 24.3 1.4 0.00023 21.2 0.1 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 KFR07583.1 - 0.00019 21.7 0.2 0.0005 20.3 0.2 1.8 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 KFR07583.1 - 0.0025 17.6 2.3 0.0091 15.8 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain P5CR_dimer PF14748.6 KFR07584.1 - 1.4e-35 121.6 2.2 2.5e-35 120.8 2.2 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KFR07584.1 - 5.4e-16 58.9 0.1 2.9e-15 56.6 0.0 2.2 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 KFR07584.1 - 0.0071 16.2 0.6 0.013 15.3 0.6 1.5 1 0 0 1 1 1 1 Rossmann-like domain ApbA PF02558.16 KFR07584.1 - 0.012 15.3 0.5 0.047 13.3 0.1 2.2 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KFR07584.1 - 0.017 15.1 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Epimerase PF01370.21 KFR07585.1 - 8.5e-46 156.4 0.0 1.1e-45 156.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFR07585.1 - 8.7e-07 28.6 0.0 1.1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Complex1_LYR PF05347.15 KFR07598.1 - 3.6e-08 33.3 0.9 4.9e-08 32.9 0.9 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) HIT PF01230.23 KFR07599.1 - 1.1e-24 87.0 0.0 1.2e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KFR07599.1 - 1.2e-14 54.7 0.0 1.3e-14 54.6 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF4707 PF15806.5 KFR07603.1 - 2.2e-233 775.0 0.1 2.4e-233 774.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4707) STAG PF08514.11 KFR07604.1 - 2.7e-33 114.3 0.0 3e-33 114.1 0.0 1.0 1 0 0 1 1 1 1 STAG domain Cnd3 PF12719.7 KFR07605.1 - 0.013 14.8 0.1 0.023 13.9 0.1 1.5 1 1 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain YcbB PF08664.10 KFR07605.1 - 0.028 14.5 0.0 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 YcbB domain Cnd1 PF12717.7 KFR07605.1 - 0.11 12.5 0.0 0.34 11.0 0.0 1.8 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 CARD_2 PF16739.5 KFR07605.1 - 0.18 11.8 1.0 2.1 8.4 0.3 2.4 2 0 0 2 2 2 0 Caspase recruitment domain Adap_comp_sub PF00928.21 KFR07606.1 - 5.4e-59 199.7 0.0 6e-59 199.6 0.0 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family MCM_OB PF17207.3 KFR07607.1 - 4.5e-35 120.3 0.7 7e-35 119.6 0.7 1.2 1 0 0 1 1 1 1 MCM OB domain zf_UBZ PF18439.1 KFR07607.1 - 0.28 10.8 1.4 5.9 6.6 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger SDF PF00375.18 KFR07611.1 - 2.9e-98 329.5 20.1 3.4e-98 329.2 20.1 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Ras PF00071.22 KFR07635.1 - 2.2e-43 147.6 0.1 2.5e-43 147.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR07635.1 - 2.1e-33 115.1 0.2 2.5e-33 114.9 0.2 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR07635.1 - 4.2e-17 62.1 0.0 4.9e-17 61.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFR07635.1 - 2.4e-10 40.5 0.1 2.9e-10 40.2 0.1 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFR07635.1 - 2.5e-06 27.0 0.0 3e-06 26.8 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFR07635.1 - 4e-05 23.2 0.0 0.00015 21.4 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFR07635.1 - 5.4e-05 22.7 0.0 6.8e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 KFR07635.1 - 0.008 16.3 0.0 0.0094 16.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.18 KFR07635.1 - 0.016 14.7 0.1 0.02 14.4 0.1 1.4 1 1 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.23 KFR07635.1 - 0.017 15.1 0.0 0.049 13.7 0.0 1.6 1 1 1 2 2 2 0 Dynamin family AAA PF00004.29 KFR07635.1 - 0.038 14.4 0.0 0.06 13.8 0.0 1.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 KFR07635.1 - 0.038 13.1 0.5 5.3 6.1 0.1 2.5 1 1 1 2 2 2 0 G-protein alpha subunit ATP_bind_1 PF03029.17 KFR07635.1 - 0.067 13.0 0.0 3.6 7.3 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.18 KFR07635.1 - 0.083 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Septin RsgA_GTPase PF03193.16 KFR07635.1 - 0.099 12.5 0.0 10 6.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase OKR_DC_1_N PF03709.15 KFR07635.1 - 0.13 12.6 0.0 0.22 11.8 0.0 1.4 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain PrmA PF06325.13 KFR07636.1 - 5.3e-09 35.9 0.0 8.5e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KFR07636.1 - 2.5e-08 34.5 0.0 5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFR07636.1 - 8.9e-07 29.5 0.0 2.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFR07636.1 - 0.00018 21.3 0.1 0.0004 20.2 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFR07636.1 - 0.00028 20.7 0.0 0.00051 19.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KFR07636.1 - 0.0013 18.3 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.14 KFR07636.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 KFR07636.1 - 0.0037 16.2 0.0 0.0053 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 KFR07636.1 - 0.0045 17.7 0.0 0.0078 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFR07636.1 - 0.016 15.0 0.2 0.035 13.9 0.1 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 KFR07636.1 - 0.021 14.6 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase CMAS PF02353.20 KFR07636.1 - 0.031 13.6 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 KFR07636.1 - 0.049 13.6 0.1 0.083 12.8 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain PRMT5_C PF17286.2 KFR07636.1 - 0.089 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 PRMT5 oligomerisation domain PRMT5 PF05185.16 KFR07636.1 - 0.09 12.6 0.2 0.18 11.6 0.2 1.5 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.6 KFR07636.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MIF4G PF02854.19 KFR07637.1 - 1e-30 107.0 0.2 1.3e-30 106.6 0.2 1.1 1 0 0 1 1 1 1 MIF4G domain PAM2 PF07145.15 KFR07637.1 - 0.0017 17.9 0.0 0.0041 16.7 0.0 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region DUF4520 PF15016.6 KFR07638.1 - 2.5e-35 120.5 0.0 5.5e-35 119.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4520) DUF4524 PF15025.6 KFR07638.1 - 3.5e-30 104.7 0.0 6.3e-29 100.6 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4524) DUF4964 PF16334.5 KFR07638.1 - 0.046 13.3 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) YdjM PF04307.14 KFR07639.1 - 0.00021 20.6 9.1 0.00065 19.0 9.3 1.7 1 1 1 2 2 2 1 LexA-binding, inner membrane-associated putative hydrolase HMG_CoA_synt_N PF01154.17 KFR07640.1 - 3.6e-108 359.1 0.5 5.1e-108 358.6 0.5 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 KFR07640.1 - 1e-105 353.4 0.4 1.5e-105 352.8 0.4 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III PF08545.10 KFR07640.1 - 0.0032 17.3 0.1 0.0083 16.0 0.1 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Pkinase PF00069.25 KFR07642.1 - 6.8e-71 238.7 0.0 1.1e-70 238.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR07642.1 - 4.8e-40 137.5 0.0 6.8e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR07642.1 - 5.7e-10 39.0 0.0 8.9e-10 38.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFR07642.1 - 0.00027 20.6 0.1 0.00045 19.9 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KFR07642.1 - 0.004 16.5 0.1 0.0068 15.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family IFN-gamma PF00714.17 KFR07642.1 - 0.064 13.1 1.2 0.44 10.4 0.0 2.3 1 1 1 2 2 2 0 Interferon gamma FlgM PF04316.13 KFR07642.1 - 0.11 12.9 0.0 0.37 11.2 0.0 1.9 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM FYRC PF05965.14 KFR07642.1 - 0.14 12.4 0.1 9.2 6.5 0.0 3.1 3 0 0 3 3 3 0 F/Y rich C-terminus BTB PF00651.31 KFR07643.1 - 6.5e-23 81.1 0.5 1.9e-22 79.6 0.5 1.9 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 KFR07643.1 - 4.1e-08 33.3 41.5 0.082 13.4 8.7 5.6 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR07643.1 - 6e-08 32.9 47.2 0.032 15.0 0.2 6.0 6 0 0 6 6 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFR07643.1 - 3.9e-07 30.2 41.0 0.21 12.1 4.9 6.6 6 0 0 6 6 6 5 Zinc-finger double domain zf-met PF12874.7 KFR07643.1 - 1.6e-05 25.1 24.6 0.0034 17.7 0.3 5.6 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFR07643.1 - 0.0064 16.8 0.4 0.0064 16.8 0.4 5.6 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFR07643.1 - 0.0082 16.1 1.8 0.0082 16.1 1.8 5.4 5 1 0 5 5 5 2 C2H2-type zinc finger zf-AD PF07776.15 KFR07643.1 - 0.085 13.1 9.7 2.3 8.5 0.9 3.6 2 1 0 3 3 3 0 Zinc-finger associated domain (zf-AD) GAGA PF09237.11 KFR07643.1 - 0.1 12.4 0.4 2.5 8.0 0.0 2.8 2 0 0 2 2 2 0 GAGA factor PHD_Oberon PF07227.11 KFR07643.1 - 0.35 10.8 9.1 1.8 8.4 2.4 2.8 1 1 1 2 2 2 0 PHD - plant homeodomain finger protein zf-CHCC PF10276.9 KFR07643.1 - 1.3 9.2 4.2 1.6 8.8 0.3 2.8 3 0 0 3 3 3 0 Zinc-finger domain zf-C2HC_2 PF13913.6 KFR07643.1 - 1.8 8.5 12.1 0.35 10.8 0.9 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 KFR07643.1 - 8 6.9 28.7 0.73 10.2 1.5 5.5 3 2 2 5 5 5 0 C2H2 type zinc-finger (2 copies) SelP_N PF04592.14 KFR07644.1 - 1.1e-41 142.7 15.2 1.2e-41 142.6 15.2 1.0 1 0 0 1 1 1 1 Selenoprotein P, N terminal region Zip PF02535.22 KFR07644.1 - 0.49 9.6 6.1 0.48 9.6 6.1 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter COMP PF11598.8 KFR07645.1 - 0.0083 16.6 0.9 0.0083 16.6 0.9 3.0 4 0 0 4 4 4 1 Cartilage oligomeric matrix protein Pox_A_type_inc PF04508.12 KFR07645.1 - 0.019 14.8 1.0 0.019 14.8 1.0 3.9 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Peptidase_Prp PF04327.12 KFR07645.1 - 0.11 12.8 0.7 0.11 12.8 0.7 2.6 2 1 0 2 2 2 0 Cysteine protease Prp Cnn_1N PF07989.11 KFR07645.1 - 0.87 9.8 29.8 0.3 11.3 9.6 3.4 1 1 1 3 3 3 0 Centrosomin N-terminal motif 1 DUF5320 PF17253.2 KFR07645.1 - 2.7 9.1 11.0 2.7 9.1 0.6 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5320) SYCP2_SLD PF18584.1 KFR07645.1 - 3.8 7.8 12.9 0.3 11.3 4.1 2.4 1 1 1 2 2 2 0 Synaptonemal complex 2 Spt16M-like domain GHBP PF12772.7 KFR07646.1 - 2.5e-134 447.5 12.3 2.9e-134 447.3 12.3 1.0 1 0 0 1 1 1 1 Growth hormone receptor binding Nab6_mRNP_bdg PF10567.9 KFR07646.1 - 0.092 12.2 1.8 0.11 11.9 0.3 1.8 2 0 0 2 2 2 0 RNA-recognition motif NinF PF05810.12 KFR07646.1 - 0.35 10.8 4.2 0.89 9.5 1.1 2.6 1 1 1 2 2 2 0 NinF protein Ricin_B_lectin PF00652.22 KFR07646.1 - 0.42 10.9 5.6 0.24 11.6 0.5 2.8 4 0 0 4 4 4 0 Ricin-type beta-trefoil lectin domain zf-RING_2 PF13639.6 KFR07664.1 - 1.7e-05 25.1 9.5 2.8e-05 24.3 9.5 1.4 1 0 0 1 1 1 1 Ring finger domain Zn_ribbon_17 PF17120.5 KFR07664.1 - 0.00018 21.0 6.6 0.0003 20.4 6.6 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KFR07664.1 - 0.00091 19.5 8.9 0.002 18.4 8.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING-like PF08746.11 KFR07664.1 - 0.014 15.6 5.4 0.025 14.9 5.4 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3HC4 PF00097.25 KFR07664.1 - 0.022 14.6 10.4 0.044 13.7 10.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFR07664.1 - 0.12 12.4 8.2 0.26 11.3 8.2 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFR07664.1 - 0.12 12.4 9.8 0.25 11.4 9.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 KFR07664.1 - 0.17 11.9 7.0 0.33 11.0 7.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 KFR07664.1 - 0.21 11.8 8.6 0.39 10.9 8.6 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.6 KFR07664.1 - 0.34 10.8 11.9 0.65 9.9 11.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFR07664.1 - 0.74 9.7 9.3 1.4 8.8 9.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KFR07664.1 - 3.7 7.4 6.0 10 6.0 6.0 1.8 1 0 0 1 1 1 0 RING-like zinc finger Peptidase_S8 PF00082.22 KFR07665.1 - 8.3e-45 153.3 1.9 1.1e-44 153.0 1.9 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KFR07665.1 - 1.9e-27 95.1 0.0 4.2e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KFR07665.1 - 5.3e-07 30.3 0.3 1.1e-06 29.3 0.3 1.6 1 0 0 1 1 1 1 Peptidase S8 pro-domain Peptidase_S8_N PF16361.5 KFR07665.1 - 0.00082 19.9 0.2 0.0017 18.9 0.2 1.4 1 0 0 1 1 1 1 N-terminal of Subtilase family Cohesin_HEAT PF12765.7 KFR07668.1 - 7.7e-12 45.3 0.2 9.8e-12 45.0 0.2 1.1 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 KFR07668.1 - 0.0021 18.2 0.5 1.3 9.5 0.0 2.3 2 0 0 2 2 2 2 HEAT repeat HEAT_EZ PF13513.6 KFR07668.1 - 0.027 15.0 0.3 0.4 11.3 0.2 2.1 1 1 1 2 2 2 0 HEAT-like repeat NRBF2_MIT PF17169.4 KFR07668.1 - 0.076 13.2 0.0 0.088 13.1 0.0 1.1 1 0 0 1 1 1 0 MIT domain of nuclear receptor-binding factor 2 Nipped-B_C PF12830.7 KFR07669.1 - 1.4e-68 230.6 4.1 1.8e-68 230.2 1.3 2.4 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus HEAT_2 PF13646.6 KFR07669.1 - 0.00046 20.5 0.0 2.4 8.6 0.0 3.3 2 1 0 2 2 2 2 HEAT repeats DNA_repr_REX1B PF14966.6 KFR07669.1 - 0.013 16.1 0.0 0.037 14.7 0.0 1.7 1 0 0 1 1 1 0 DNA repair REX1-B HEAT PF02985.22 KFR07669.1 - 0.028 14.7 0.1 1.3e+02 3.3 0.0 5.1 6 0 0 6 6 6 0 HEAT repeat HEAT_EZ PF13513.6 KFR07669.1 - 0.044 14.3 0.0 4.7 7.8 0.0 3.9 4 0 0 4 4 4 0 HEAT-like repeat Cnd1 PF12717.7 KFR07669.1 - 0.048 13.7 5.5 1.3 9.1 0.0 3.4 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 BP28CT PF08146.12 KFR07669.1 - 0.064 13.1 0.3 0.39 10.5 0.1 2.4 2 0 0 2 2 2 0 BP28CT (NUC211) domain T3SS_basalb_I PF17001.5 KFR07669.1 - 0.12 13.0 4.4 0.63 10.7 1.8 2.8 3 0 0 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI RRM_1 PF00076.22 KFR07680.1 - 1.6e-13 50.2 0.1 3e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFR07680.1 - 0.003 17.1 0.1 0.0088 15.6 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1029 PF06269.12 KFR07680.1 - 0.23 11.6 0.3 0.4 10.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1029) BTB PF00651.31 KFR07681.1 - 9.7e-23 80.5 0.0 1.2e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain Tap-RNA_bind PF09162.10 KFR07695.1 - 4.6e-34 116.1 0.1 8.6e-34 115.2 0.1 1.5 1 0 0 1 1 1 1 Tap, RNA-binding NTF2 PF02136.20 KFR07695.1 - 5.3e-25 88.3 0.0 1e-24 87.4 0.0 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_4 PF12799.7 KFR07695.1 - 9.5e-07 29.1 3.3 0.037 14.5 0.1 3.0 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFR07695.1 - 5e-06 26.2 2.5 1.5e-05 24.6 2.5 1.9 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.33 KFR07695.1 - 0.00069 19.8 2.5 30 5.7 0.2 4.4 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.6 KFR07695.1 - 0.094 12.8 2.3 20 5.6 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich repeat TMEM223 PF14640.6 KFR07696.1 - 3.2e-57 193.3 0.0 3.6e-57 193.1 0.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 223 LicD PF04991.13 KFR07704.1 - 2.8e-13 50.5 0.0 1.5e-11 44.9 0.1 2.1 2 0 0 2 2 2 2 LicD family WD40 PF00400.32 KFR07706.1 - 0.11 13.4 0.3 5.8 7.9 0.0 2.2 2 0 0 2 2 2 0 WD domain, G-beta repeat Cadherin PF00028.17 KFR07716.1 - 7.3e-98 321.2 11.4 6.2e-20 71.4 0.1 7.4 7 0 0 7 7 7 7 Cadherin domain Protocadherin PF08374.11 KFR07716.1 - 2.7e-76 256.4 0.6 4.6e-76 255.6 0.6 1.4 1 0 0 1 1 1 1 Protocadherin Cadherin_2 PF08266.12 KFR07716.1 - 5.2e-20 71.1 0.1 3.1e-08 33.3 0.0 6.1 6 0 0 6 6 6 4 Cadherin-like Cadherin_3 PF16184.5 KFR07716.1 - 4.9e-08 32.9 16.9 0.19 11.7 0.1 6.1 6 0 0 6 6 6 4 Cadherin-like RET_CLD1 PF17756.1 KFR07716.1 - 0.00026 21.3 0.0 0.27 11.5 0.0 3.2 3 1 0 3 3 3 1 RET Cadherin like domain 1 EphA2_TM PF14575.6 KFR07716.1 - 0.0031 18.4 0.3 0.0073 17.2 0.3 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Cadherin_4 PF17803.1 KFR07716.1 - 0.012 16.2 26.5 0.032 14.9 0.9 5.6 5 0 0 5 5 5 0 Bacterial cadherin-like domain AP3D1 PF06375.11 KFR07716.1 - 0.019 15.2 0.1 0.042 14.1 0.1 1.5 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 He_PIG PF05345.12 KFR07716.1 - 0.019 15.1 8.0 22 5.3 0.0 5.6 5 0 0 5 5 5 0 Putative Ig domain V_ATPase_I PF01496.19 KFR07716.1 - 0.041 11.8 0.0 0.059 11.3 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Big_9 PF17963.1 KFR07716.1 - 0.074 13.8 0.5 0.074 13.8 0.5 6.3 6 0 0 6 6 6 0 Bacterial Ig domain Shisa PF13908.6 KFR07716.1 - 0.08 13.2 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator LLGL PF08366.13 KFR07729.1 - 3.9e-08 33.6 0.0 1e-07 32.3 0.0 1.7 1 0 0 1 1 1 1 LLGL2 Lgl_C PF08596.10 KFR07729.1 - 0.024 13.3 0.0 0.062 12.0 0.0 1.6 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal tRNA_int_end_N2 PF12928.7 KFR07730.1 - 5.7e-17 61.7 0.1 1.7e-16 60.1 0.1 1.9 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term SH3_1 PF00018.28 KFR07732.1 - 6.6e-36 121.7 0.3 8.4e-17 60.5 0.1 2.6 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 KFR07732.1 - 3.8e-32 109.9 0.2 1.8e-15 56.5 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KFR07732.1 - 3.1e-28 97.2 0.0 1.1e-15 57.0 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH2 PF00017.24 KFR07732.1 - 1.3e-24 86.1 0.0 2.1e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 SH2 domain SH3_10 PF17902.1 KFR07732.1 - 1.6e-06 28.0 0.0 0.00048 20.2 0.0 2.5 2 1 0 2 2 2 1 SH3 domain SH2_2 PF14633.6 KFR07732.1 - 0.0043 16.5 0.0 0.0062 16.0 0.0 1.3 1 0 0 1 1 1 1 SH2 domain hSH3 PF14603.6 KFR07732.1 - 0.0074 16.7 0.0 0.078 13.4 0.0 2.3 2 0 0 2 2 2 1 Helically-extended SH3 domain SH3_3 PF08239.11 KFR07732.1 - 0.0077 16.5 0.1 0.054 13.8 0.0 2.1 2 0 0 2 2 2 1 Bacterial SH3 domain DUF5093 PF17011.5 KFR07732.1 - 0.019 15.2 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5093) SH3_4 PF06347.13 KFR07732.1 - 0.029 14.2 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain Mito_carr PF00153.27 KFR07733.1 - 4e-65 215.8 1.6 2.5e-22 78.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S7 PF00177.21 KFR07734.1 - 1.2e-40 138.6 0.2 1.6e-40 138.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF719 PF05334.13 KFR07734.1 - 0.016 15.4 0.4 0.036 14.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF719) VHS PF00790.19 KFR07735.1 - 1.3e-42 145.0 2.0 5e-42 143.1 0.0 2.4 2 1 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 KFR07735.1 - 3.1e-31 108.0 0.0 8e-31 106.6 0.0 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 KFR07735.1 - 4.6e-21 74.2 6.7 4.6e-21 74.2 6.7 2.0 2 0 0 2 2 2 1 GGA N-GAT domain GAT PF03127.14 KFR07735.1 - 1.4e-20 73.3 2.7 1.4e-20 73.3 2.7 2.5 2 0 0 2 2 2 1 GAT domain AP3B1_C PF14796.6 KFR07735.1 - 0.032 14.5 2.0 0.64 10.3 0.0 2.8 3 0 0 3 3 3 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal HD_2 PF12917.7 KFR07735.1 - 0.039 13.7 1.2 0.077 12.7 1.2 1.5 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme SesA PF17107.5 KFR07735.1 - 0.04 14.1 0.8 0.095 12.9 0.8 1.7 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases HBM PF16591.5 KFR07735.1 - 0.16 11.3 2.8 0.28 10.6 2.8 1.3 1 0 0 1 1 1 0 Helical bimodular sensor domain PCRF PF03462.18 KFR07735.1 - 2.2 8.1 5.5 3.8 7.3 5.5 1.3 1 0 0 1 1 1 0 PCRF domain zf-C4H2 PF10146.9 KFR07735.1 - 3 8.1 9.7 3.9e+02 1.2 9.7 2.5 1 1 0 1 1 1 0 Zinc finger-containing protein Rad60-SLD PF11976.8 KFR07736.1 - 4.2e-26 90.6 0.1 5e-26 90.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KFR07736.1 - 2.2e-12 46.5 0.1 2.6e-12 46.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family JUPITER PF17054.5 KFR07737.1 - 0.00064 19.3 0.7 0.00086 18.9 0.1 1.5 2 0 0 2 2 2 1 Microtubule-Associated protein Jupiter NT5C PF06941.12 KFR07738.1 - 2.9e-17 63.1 0.0 3.5e-17 62.9 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Arm PF00514.23 KFR07739.1 - 1.4e-11 44.0 0.0 5.8e-06 26.2 0.0 3.0 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat RICTOR_N PF14664.6 KFR07739.1 - 0.0019 17.2 0.3 0.0041 16.2 0.2 1.5 1 1 1 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term Arm_2 PF04826.13 KFR07739.1 - 0.01 15.3 0.1 2 7.8 0.1 2.0 1 1 1 2 2 2 0 Armadillo-like Glycoprotein PF03409.15 KFR07739.1 - 0.042 12.7 0.1 0.053 12.4 0.1 1.1 1 0 0 1 1 1 0 Transmembrane glycoprotein HEAT_2 PF13646.6 KFR07739.1 - 0.098 13.1 0.0 2.8 8.4 0.0 2.3 1 1 1 2 2 2 0 HEAT repeats BTB_2 PF02214.22 KFR07740.1 - 9.5e-12 45.1 0.0 1.6e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KFR07740.1 - 0.011 16.0 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain SAM_LFY PF01698.16 KFR07740.1 - 0.058 13.3 0.2 0.37 10.8 0.0 2.0 2 0 0 2 2 2 0 Floricaula / Leafy protein SAM domain Mt_ATP-synt_D PF05873.12 KFR07741.1 - 1.5e-66 223.0 6.5 1.7e-66 222.8 6.5 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) GIDA_assoc PF13932.6 KFR07741.1 - 0.026 14.7 0.3 0.036 14.3 0.3 1.2 1 0 0 1 1 1 0 GidA associated domain DUF4265 PF14085.6 KFR07741.1 - 0.057 13.4 0.0 0.09 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) Gp-FAR-1 PF05823.12 KFR07741.1 - 0.062 13.7 5.9 0.93 9.8 5.9 2.1 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Exonuc_VII_L PF02601.15 KFR07741.1 - 0.062 12.9 0.3 0.076 12.6 0.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Neur_chan_LBD PF02931.23 KFR07742.1 - 1.3e-20 73.8 3.0 1.5e-20 73.6 3.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFR07742.1 - 0.02 15.0 1.1 0.075 13.1 1.7 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RF-1 PF00472.20 KFR07743.1 - 1.6e-18 66.7 4.1 1.8e-18 66.5 4.1 1.0 1 0 0 1 1 1 1 RF-1 domain TFX_C PF14601.6 KFR07743.1 - 0.06 13.3 0.7 0.14 12.1 0.7 1.5 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term Orbi_VP4 PF05059.12 KFR07744.1 - 0.01 13.9 0.1 0.015 13.3 0.1 1.2 1 0 0 1 1 1 0 Orbivirus VP4 core protein zf-ZPR1 PF03367.13 KFR07744.1 - 0.027 14.3 0.3 0.027 14.3 0.3 3.8 3 1 1 4 4 4 0 ZPR1 zinc-finger domain DUF3540 PF12059.8 KFR07744.1 - 0.47 10.3 12.6 0.49 10.2 1.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3540) Lectin_N PF03954.14 KFR07744.1 - 0.54 10.0 23.9 0.052 13.3 1.2 4.6 3 1 0 4 4 4 0 Hepatic lectin, N-terminal domain FliD_C PF07195.12 KFR07744.1 - 4.7 6.6 19.7 0.54 9.6 4.9 3.7 3 1 0 4 4 4 0 Flagellar hook-associated protein 2 C-terminus BLOC1_2 PF10046.9 KFR07744.1 - 5.8 7.3 37.9 0.068 13.5 13.9 4.9 4 2 3 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 KFR07744.1 - 6.4 5.6 49.6 0.37 9.6 17.8 3.2 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF1664 PF07889.12 KFR07744.1 - 6.8 6.7 32.7 1.9 8.5 4.9 4.5 4 2 1 5 5 5 0 Protein of unknown function (DUF1664) AIP3 PF03915.13 KFR07744.1 - 8 5.4 34.7 1.2 8.2 11.5 3.2 3 0 0 3 3 3 0 Actin interacting protein 3 DUF1003 PF06210.11 KFR07744.1 - 9.8 6.3 16.3 1.2 9.3 2.6 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1003) Hid1 PF12722.7 KFR07745.1 - 1e-275 917.0 0.0 1.2e-275 916.7 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KFR07745.1 - 3.2e-258 858.3 0.0 3.6e-258 858.2 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Otopetrin PF03189.13 KFR07746.1 - 2.6e-39 135.3 38.8 3.8e-17 62.3 11.4 4.5 3 1 1 4 4 4 3 Otopetrin REC114-like PF15165.6 KFR07746.1 - 0.043 13.6 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like Otopetrin PF03189.13 KFR07747.1 - 3e-52 177.9 34.5 6e-23 81.4 6.3 4.4 3 1 0 4 4 4 3 Otopetrin SdpI PF13630.6 KFR07747.1 - 0.012 15.7 2.0 0.012 15.7 2.0 4.0 3 0 0 3 3 3 0 SdpI/YhfL protein family DUF5345 PF17280.2 KFR07747.1 - 0.078 13.0 0.1 0.078 13.0 0.1 3.4 3 1 0 3 3 3 0 Family of unknown function (DUF5345) VPDSG-CTERM PF18205.1 KFR07747.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.8 2 0 0 2 2 2 0 VPDSG-CTERM motif Orf78 PF06024.12 KFR07747.1 - 0.21 11.9 3.1 0.95 9.8 0.9 2.8 2 0 0 2 2 2 0 Orf78 (ac78) Adipogenin PF15202.6 KFR07747.1 - 0.48 10.5 5.9 0.11 12.5 0.6 2.7 3 0 0 3 3 3 0 Adipogenin Cation_ATPase_C PF00689.21 KFR07747.1 - 1.2 8.9 14.8 0.81 9.4 1.6 3.3 2 1 0 3 3 3 0 Cation transporting ATPase, C-terminus DUF4149 PF13664.6 KFR07747.1 - 1.3 9.4 11.7 1.8 9.0 1.9 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) Ank_2 PF12796.7 KFR07748.1 - 9.2e-29 99.9 0.5 1.9e-15 57.2 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFR07748.1 - 2.3e-22 79.0 4.5 2.8e-12 46.9 0.2 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFR07748.1 - 3.1e-13 49.5 2.5 3.2e-07 30.5 0.2 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KFR07748.1 - 1.3e-12 47.7 1.1 4.7e-07 30.0 0.3 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFR07748.1 - 1.7e-12 46.4 0.8 4.5e-05 23.5 0.2 4.0 4 0 0 4 4 4 3 Ankyrin repeat SAM_1 PF00536.30 KFR07748.1 - 1.6e-10 41.3 0.1 8.9e-10 38.9 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SR-25 PF10500.9 KFR07748.1 - 3.1 7.3 13.0 5.2 6.6 13.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FA_desaturase PF00487.24 KFR07749.1 - 3.9e-12 46.5 10.9 5.5e-12 46.1 10.9 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Pyr_redox_2 PF07992.14 KFR07750.1 - 3.2e-12 46.3 0.1 8.4e-08 31.8 0.1 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFR07750.1 - 0.00011 22.4 0.0 0.00025 21.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KFR07750.1 - 0.04 13.9 0.0 0.095 12.7 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KFR07750.1 - 0.078 11.7 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Lig_chan-Glu_bd PF10613.9 KFR07751.1 - 6.4e-29 100.5 0.1 9.8e-28 96.7 0.0 2.2 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.28 KFR07751.1 - 6.4e-19 68.3 0.3 9e-18 64.5 0.3 2.1 1 1 0 1 1 1 1 Receptor family ligand binding region SBP_bac_3 PF00497.20 KFR07751.1 - 6.6e-19 68.2 0.0 6.3e-10 38.9 0.0 2.4 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 KFR07751.1 - 9.5e-19 67.7 2.0 4.3e-13 49.4 3.0 2.5 2 0 0 2 2 2 2 Ligand-gated ion channel NMDAR2_C PF10565.9 KFR07751.1 - 5.3e-13 48.7 0.0 6.4e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 N-methyl D-aspartate receptor 2B3 C-terminus MatE PF01554.18 KFR07751.1 - 0.09 12.4 1.2 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 MatE Peripla_BP_4 PF13407.6 KFR07751.1 - 0.13 11.9 0.0 12 5.4 0.0 2.4 1 1 1 2 2 2 0 Periplasmic binding protein domain Aa_trans PF01490.18 KFR07752.1 - 2.2e-19 69.5 32.2 5e-11 41.9 21.0 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KFR07752.1 - 1e-07 31.4 20.6 0.00069 18.8 1.4 2.5 2 1 0 2 2 2 2 Tryptophan/tyrosine permease family Cytomega_UL84 PF06284.11 KFR07752.1 - 0.072 11.5 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Acetyltransf_3 PF13302.7 KFR07753.1 - 5.9e-22 78.8 0.0 8.5e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFR07753.1 - 7.1e-05 22.7 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 KFR07753.1 - 0.0018 18.5 0.0 0.0025 18.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family EBP50_C PF09007.11 KFR07754.1 - 2.9e-38 131.8 0.1 4.2e-38 131.3 0.1 1.3 1 0 0 1 1 1 1 EBP50, C-terminal PDZ_6 PF17820.1 KFR07754.1 - 1.5e-16 59.9 0.5 2.4e-16 59.3 0.5 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFR07754.1 - 4.8e-14 52.5 0.0 7.2e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFR07754.1 - 1.1e-06 28.8 0.1 2e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KFR07754.1 - 0.034 14.5 0.0 0.049 13.9 0.0 1.2 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Ras PF00071.22 KFR07755.1 - 3.4e-59 199.1 0.1 4e-59 198.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR07755.1 - 1.8e-32 112.1 0.1 2.6e-32 111.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR07755.1 - 4.3e-14 52.3 0.1 4.7e-14 52.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFR07755.1 - 4.4e-06 26.2 0.0 5.6e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KFR07755.1 - 0.00023 21.1 0.2 0.14 12.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFR07755.1 - 0.002 18.2 0.0 0.0035 17.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 KFR07755.1 - 0.023 14.4 0.1 0.033 13.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 KFR07755.1 - 0.035 13.4 0.1 0.091 12.0 0.1 1.7 1 1 0 1 1 1 0 Septin DAP3 PF10236.9 KFR07755.1 - 0.063 12.4 0.1 0.14 11.3 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 KFR07755.1 - 0.064 13.6 0.1 0.15 12.5 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain V-set PF07686.17 KFR07756.1 - 8.6e-12 45.2 0.0 9.7e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFR07756.1 - 0.0029 17.8 0.0 0.12 12.6 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 KFR07756.1 - 0.021 15.4 0.1 0.073 13.7 0.1 1.9 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KFR07757.1 - 5.3e-06 26.6 0.0 5.4e-06 26.5 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFR07757.1 - 8e-05 22.7 0.1 8.2e-05 22.7 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFR07757.1 - 0.018 15.7 0.0 0.018 15.7 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFR07757.1 - 0.042 13.9 0.0 0.042 13.9 0.0 1.0 1 0 0 1 1 1 0 Immunoglobulin I-set domain Izumo-Ig PF16706.5 KFR07757.1 - 0.081 13.0 0.1 0.081 13.0 0.1 1.1 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Xylo_C PF12529.8 KFR07758.1 - 2.8e-70 235.6 0.0 4.3e-70 235.0 0.0 1.3 1 0 0 1 1 1 1 Xylosyltransferase C terminal Branch PF02485.21 KFR07758.1 - 3.2e-55 187.3 1.7 4.4e-55 186.9 1.7 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Ribosomal_L27 PF01016.19 KFR07759.1 - 2.4e-24 85.2 0.1 3.1e-24 84.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein ERCC4 PF02732.15 KFR07760.1 - 2.7e-10 40.7 0.0 5.2e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain WASH-7_mid PF14744.6 KFR07760.1 - 0.024 13.8 0.1 0.036 13.2 0.1 1.2 1 0 0 1 1 1 0 WASH complex subunit 7 BRF1 PF07741.13 KFR07760.1 - 4.4 7.7 12.7 1.4 9.3 0.7 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain LRR_8 PF13855.6 KFR07761.1 - 1.1e-13 50.7 17.0 1.5e-10 40.6 8.3 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFR07761.1 - 9.6e-11 41.8 13.5 1.9e-06 28.1 3.0 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFR07761.1 - 5.1e-05 23.3 11.6 6 7.8 0.4 4.7 4 0 0 4 4 4 2 Leucine Rich Repeat GAGA_bind PF06217.12 KFR07761.1 - 0.0075 16.6 8.2 0.0098 16.2 8.2 1.2 1 0 0 1 1 1 1 GAGA binding protein-like family DUF5427 PF10310.9 KFR07761.1 - 0.013 14.5 9.1 0.016 14.2 9.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) GREB1 PF15782.5 KFR07761.1 - 0.045 10.9 8.4 0.051 10.7 8.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LAP1C PF05609.12 KFR07761.1 - 0.062 12.4 10.8 0.078 12.1 10.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) MAJIN PF15077.6 KFR07761.1 - 0.14 11.9 9.8 0.2 11.4 9.8 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein DDHD PF02862.17 KFR07761.1 - 0.14 12.3 3.6 0.17 12.0 3.6 1.2 1 0 0 1 1 1 0 DDHD domain LRR_6 PF13516.6 KFR07761.1 - 0.55 10.4 13.5 4.1 7.7 0.2 4.4 4 0 0 4 4 4 0 Leucine Rich repeat ALMT PF11744.8 KFR07761.1 - 0.83 8.4 7.7 1.1 8.0 7.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Hydin_ADK PF17213.3 KFR07761.1 - 0.96 9.7 10.8 1.5 9.1 10.8 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Atrophin-1 PF03154.15 KFR07761.1 - 1.2 7.3 20.8 1.8 6.7 20.8 1.4 1 0 0 1 1 1 0 Atrophin-1 family Sec62 PF03839.16 KFR07761.1 - 1.3 8.5 10.9 1.9 7.9 10.9 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4366 PF14283.6 KFR07761.1 - 1.8 8.6 7.8 20 5.2 7.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Orf78 PF06024.12 KFR07761.1 - 2.2 8.6 4.5 45 4.4 4.5 2.5 1 1 0 1 1 1 0 Orf78 (ac78) Borrelia_P83 PF05262.11 KFR07761.1 - 2.7 6.4 21.0 3.4 6.1 21.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Neur_chan_memb PF02932.16 KFR07761.1 - 2.9 7.9 6.8 4 7.4 6.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PBP1_TM PF14812.6 KFR07761.1 - 5.3 7.5 16.4 46 4.5 16.4 2.1 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4407 PF14362.6 KFR07761.1 - 6.3 6.1 10.8 9.3 5.5 10.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.12 KFR07761.1 - 6.8 6.4 19.8 9.4 6.0 19.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 XRN_M PF17846.1 KFR07761.1 - 9.4 5.1 13.0 14 4.5 13.0 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Red1 PF07964.11 KFR07761.1 - 9.5 4.3 19.0 13 3.9 19.0 1.1 1 0 0 1 1 1 0 Rec10 / Red1 AMP-binding PF00501.28 KFR07762.1 - 1.5e-99 333.5 0.0 1.8e-99 333.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFR07762.1 - 1.5e-17 64.3 0.1 3.1e-17 63.3 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LRR_8 PF13855.6 KFR07763.1 - 1.3e-61 204.2 33.0 3.8e-18 65.0 0.1 5.4 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFR07763.1 - 1.1e-19 70.2 23.7 4.4e-05 23.8 0.1 6.8 3 2 4 8 8 8 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFR07763.1 - 4.8e-14 52.4 0.0 4.7e-06 26.6 0.0 2.6 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFR07763.1 - 2.8e-09 36.2 18.1 0.068 13.8 0.0 9.6 10 1 0 10 10 10 2 Leucine Rich Repeat LRRNT PF01462.18 KFR07763.1 - 4.6e-08 32.5 4.3 4.6e-08 32.5 4.3 2.5 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 KFR07763.1 - 1.2e-07 31.4 5.8 0.049 13.1 0.0 3.5 1 1 1 3 3 3 3 Leucine-rich repeat Rv2175c_C PF18367.1 KFR07763.1 - 0.0034 17.4 0.1 0.29 11.3 0.0 3.2 2 1 0 2 2 2 1 Rv2175c C-terminal domain of unknown function LRRCT PF01463.24 KFR07763.1 - 0.013 15.9 0.1 0.056 14.0 0.1 2.2 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain ENTH PF01417.20 KFR07764.1 - 2.2e-50 169.9 0.0 3.4e-50 169.3 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KFR07764.1 - 2.2e-05 23.6 0.0 3.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 KFR07764.1 - 0.00057 19.8 0.2 0.0021 17.9 0.1 1.9 2 0 0 2 2 2 1 VHS domain UIM PF02809.20 KFR07764.1 - 0.0096 15.8 2.7 0.0096 15.8 2.7 3.7 4 0 0 4 4 4 2 Ubiquitin interaction motif Thioredox_DsbH PF03190.15 KFR07765.1 - 5.2e-76 254.1 0.0 8.9e-76 253.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 KFR07765.1 - 2.3e-10 40.5 0.0 5.2e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like C5-epim_C PF06662.13 KFR07765.1 - 0.027 14.0 1.4 0.14 11.7 0.1 2.4 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus ERAP1_C PF11838.8 KFR07765.1 - 0.12 11.8 0.1 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 ERAP1-like C-terminal domain Thioredoxin_2 PF13098.6 KFR07765.1 - 0.18 12.3 0.0 0.4 11.2 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain ABC_membrane PF00664.23 KFR07766.1 - 9.5e-86 287.8 30.8 3.3e-47 161.4 8.2 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFR07766.1 - 7.5e-54 182.0 0.1 2.4e-28 99.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFR07766.1 - 1.5e-09 37.6 0.0 0.0013 18.2 0.0 4.0 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KFR07766.1 - 7.4e-06 26.0 0.5 0.03 14.4 0.0 2.9 3 0 0 3 3 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFR07766.1 - 0.00015 21.7 1.1 0.017 15.0 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KFR07766.1 - 0.00046 20.6 0.8 0.092 13.1 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFR07766.1 - 0.0014 18.9 0.3 3.8 7.8 0.1 3.2 2 1 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 KFR07766.1 - 0.0097 16.0 1.4 0.17 12.0 0.0 2.9 3 0 0 3 3 3 1 Dynamin family AAA_29 PF13555.6 KFR07766.1 - 0.019 14.7 1.9 2.6 7.9 0.1 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KFR07766.1 - 0.028 14.0 0.5 0.78 9.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KFR07766.1 - 0.032 14.7 4.8 2.6 8.5 0.0 3.6 4 0 0 4 4 4 0 AAA domain AAA_7 PF12775.7 KFR07766.1 - 0.033 13.7 0.6 0.91 9.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Orthoreo_P10 PF07204.11 KFR07766.1 - 0.075 13.0 1.3 0.62 10.1 0.1 3.0 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 GTP_EFTU PF00009.27 KFR07766.1 - 0.1 12.1 0.1 0.87 9.1 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF815 PF05673.13 KFR07766.1 - 0.17 11.1 1.3 1.3 8.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KFR07766.1 - 0.19 12.2 0.1 11 6.5 0.0 3.0 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 KFR07766.1 - 0.19 11.4 0.1 2.5 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain PRIMA1 PF16101.5 KFR07766.1 - 0.42 10.7 6.0 0.28 11.2 0.4 3.0 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 DUF87 PF01935.17 KFR07766.1 - 2 8.4 7.7 4.1 7.4 0.4 2.7 3 0 0 3 3 2 0 Helicase HerA, central domain NB-ARC PF00931.22 KFR07766.1 - 2.1 7.5 4.0 5.5 6.1 0.0 2.8 2 1 0 2 2 2 0 NB-ARC domain LUC7 PF03194.15 KFR07768.1 - 1.2e-89 300.3 26.9 1.2e-89 300.3 26.9 3.5 1 1 1 2 2 2 1 LUC7 N_terminus FlbD PF06289.11 KFR07769.1 - 0.099 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Flagellar and Swarming motility proteins Kunitz_BPTI PF00014.23 KFR07770.1 - 1.6e-31 108.3 34.0 1.6e-20 73.1 6.7 3.4 3 0 0 3 3 3 2 Kunitz/Bovine pancreatic trypsin inhibitor domain I-set PF07679.16 KFR07770.1 - 4.6e-17 61.9 0.0 8.7e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR07770.1 - 1.3e-14 54.6 0.3 3.6e-14 53.1 0.3 1.9 1 0 0 1 1 1 1 Immunoglobulin domain NTR PF01759.21 KFR07770.1 - 3.7e-11 42.8 0.0 8.1e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 UNC-6/NTR/C345C module ig PF00047.25 KFR07770.1 - 7.4e-10 38.9 0.0 1.5e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFR07770.1 - 9.1e-10 38.8 0.0 2.9e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain WAP PF00095.21 KFR07770.1 - 6e-08 33.0 11.0 6e-08 33.0 11.0 4.5 5 1 0 5 5 5 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' V-set PF07686.17 KFR07770.1 - 2.9e-06 27.4 1.8 2.7e-05 24.3 0.1 2.9 2 1 0 2 2 2 1 Immunoglobulin V-set domain BTG PF07742.12 KFR07771.1 - 1.4e-38 131.3 0.0 2.5e-38 130.5 0.0 1.4 1 0 0 1 1 1 1 BTG family PAM2 PF07145.15 KFR07771.1 - 4.2e-06 26.1 3.2 0.0083 15.8 0.3 2.9 2 0 0 2 2 2 2 Ataxin-2 C-terminal region NDK PF00334.19 KFR07772.1 - 1.4e-54 183.7 0.0 1.6e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Benyvirus_14KDa PF07255.11 KFR07772.1 - 0.065 13.5 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Benyvirus 14KDa protein NDK PF00334.19 KFR07773.1 - 2.9e-56 189.2 0.0 3.2e-56 189.1 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase MBT PF02820.18 KFR07774.1 - 9.6e-92 301.4 2.3 7.3e-28 96.7 0.1 4.3 4 0 0 4 4 4 4 mbt repeat C1_2 PF03107.16 KFR07774.1 - 0.028 14.7 3.0 1.7 9.0 0.0 3.4 3 0 0 3 3 3 0 C1 domain WD40 PF00400.32 KFR07775.1 - 1.7e-08 35.0 0.0 1 10.4 0.0 6.3 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR07775.1 - 4.2e-06 27.0 0.0 2.1 8.7 0.0 4.7 3 2 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Formyl_trans_C PF02911.18 KFR07775.1 - 0.091 13.0 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Formyl transferase, C-terminal domain Carb_anhydrase PF00194.21 KFR07776.1 - 5.9e-36 124.3 0.4 6.7e-36 124.1 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Glyco_transf_49 PF13896.6 KFR07779.1 - 6.8e-58 196.6 4.0 4.9e-45 154.3 1.5 2.4 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_transf_8 PF01501.20 KFR07779.1 - 3.3e-19 69.5 0.7 5.8e-19 68.6 0.7 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KFR07779.1 - 8.4e-07 28.7 3.5 1.4e-06 27.9 3.5 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Mto2_bdg PF12808.7 KFR07779.1 - 0.21 11.9 5.1 0.053 13.8 1.5 1.9 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region WD40_alt PF14077.6 KFR07779.1 - 4.5 7.2 6.5 1.2 9.1 2.3 2.2 2 0 0 2 2 2 0 Alternative WD40 repeat motif Synapsin_C PF02750.14 KFR07780.1 - 1e-132 439.9 0.3 1.4e-132 439.5 0.3 1.1 1 0 0 1 1 1 1 Synapsin, ATP binding domain Synapsin PF02078.16 KFR07780.1 - 7.6e-36 122.4 0.2 9e-35 119.0 0.0 2.5 3 0 0 3 3 3 1 Synapsin, N-terminal domain RimK PF08443.11 KFR07780.1 - 0.00084 19.0 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain TIMP PF00965.17 KFR07781.1 - 1.2e-50 171.9 5.1 1.3e-50 171.7 5.1 1.0 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase F-box-like PF12937.7 KFR07782.1 - 1.7e-10 40.6 2.8 3.3e-10 39.7 2.8 1.5 1 0 0 1 1 1 1 F-box-like PI31_Prot_N PF11566.8 KFR07782.1 - 1.4e-05 24.9 0.1 5e-05 23.2 0.0 2.0 2 1 0 2 2 2 1 PI31 proteasome regulator N-terminal F-box PF00646.33 KFR07782.1 - 3.1e-05 23.7 1.3 5.9e-05 22.8 1.3 1.5 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 KFR07782.1 - 0.011 16.2 0.3 0.011 16.2 0.3 1.6 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box_4 PF15966.5 KFR07782.1 - 0.035 14.0 0.1 0.058 13.3 0.1 1.3 1 0 0 1 1 1 0 F-box LBP_BPI_CETP_C PF02886.17 KFR07783.1 - 3.9e-40 137.8 0.2 4.9e-40 137.5 0.2 1.1 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain RtcB PF01139.17 KFR07784.1 - 1.2e-144 482.5 0.5 1.4e-144 482.3 0.5 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Cu-oxidase_4 PF02578.15 KFR07784.1 - 0.044 13.4 0.2 0.21 11.1 0.2 1.9 2 0 0 2 2 2 0 Multi-copper polyphenol oxidoreductase laccase HLH PF00010.26 KFR07785.1 - 8.6e-18 64.1 2.2 1.2e-17 63.6 2.2 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain zf_PR_Knuckle PF18445.1 KFR07786.1 - 1.2e-28 98.6 13.4 8.5e-28 95.9 3.6 4.0 3 0 0 3 3 3 2 PR zinc knuckle motif zf-H2C2_2 PF13465.6 KFR07786.1 - 4.8e-26 90.0 54.9 1.3e-07 31.7 0.7 8.3 8 1 0 8 8 8 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFR07786.1 - 8.3e-20 70.1 63.1 1.3e-05 25.4 1.8 8.5 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR07786.1 - 4.5e-17 61.3 63.7 0.00094 19.8 1.6 8.8 9 0 0 9 9 9 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFR07786.1 - 0.00011 22.4 51.3 0.027 14.7 0.2 8.1 7 1 1 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFR07786.1 - 0.00011 22.4 44.0 0.00085 19.6 1.1 7.5 7 0 0 7 7 7 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFR07786.1 - 0.0033 17.2 1.2 0.0033 17.2 1.2 6.3 6 1 0 6 6 6 3 C2H2-type zinc-finger domain Mu-like_Com PF10122.9 KFR07786.1 - 0.097 12.1 5.5 0.075 12.5 2.9 2.2 2 1 0 2 2 2 0 Mu-like prophage protein Com zf-C2H2_2 PF12756.7 KFR07786.1 - 2.1 8.7 37.5 11 6.4 10.7 5.9 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) WD40 PF00400.32 KFR07787.1 - 3.5e-13 49.8 3.4 0.0011 19.8 0.1 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR07787.1 - 3.4e-05 24.0 0.2 0.016 15.5 0.1 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain BTB PF00651.31 KFR07788.1 - 1.6e-23 83.0 0.5 9.4e-22 77.4 0.2 3.3 2 1 1 3 3 3 1 BTB/POZ domain Ank_2 PF12796.7 KFR07788.1 - 6.3e-20 71.5 0.0 1.3e-09 38.5 0.0 4.3 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFR07788.1 - 8.2e-19 65.7 0.1 1.7e-05 24.8 0.0 5.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KFR07788.1 - 5.4e-17 61.9 0.0 0.00039 20.9 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFR07788.1 - 1.2e-15 57.1 0.3 1.2e-06 28.7 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KFR07788.1 - 1.2e-14 54.1 0.1 0.0072 16.6 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeats (many copies) BACK PF07707.15 KFR07788.1 - 0.0016 18.5 0.8 0.0064 16.6 0.0 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch RVT_1 PF00078.27 KFR07789.1 - 0.0029 17.2 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAD_binding_7 PF03441.14 KFR07790.1 - 3.8e-80 268.1 0.4 6.4e-80 267.4 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KFR07790.1 - 1.8e-25 89.8 0.0 3.7e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase mTERF PF02536.14 KFR07791.1 - 6e-28 97.7 7.3 7.4e-28 97.4 7.3 1.1 1 0 0 1 1 1 1 mTERF K-box PF01486.17 KFR07791.1 - 0.024 14.8 0.9 7.1 6.9 0.0 3.6 4 0 0 4 4 4 0 K-box region RRF_GI PF12614.8 KFR07791.1 - 0.088 13.0 2.6 0.15 12.2 0.3 2.4 2 1 0 2 2 2 0 Ribosome recycling factor UPF0444 PF15475.6 KFR07792.1 - 1.1e-45 153.8 12.8 1.2e-45 153.6 12.8 1.0 1 0 0 1 1 1 1 Transmembrane protein C12orf23, UPF0444 Ric8 PF10165.9 KFR07793.1 - 6.7e-132 440.8 2.3 7.8e-132 440.6 2.3 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Rif1_N PF12231.8 KFR07793.1 - 0.0056 15.7 0.3 0.012 14.6 0.3 1.5 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal RFX_DNA_binding PF02257.15 KFR07794.1 - 1.4e-34 118.5 0.0 4.3e-34 117.0 0.0 1.9 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 KFR07794.1 - 5.8e-05 23.5 0.0 0.00016 22.1 0.0 1.7 1 0 0 1 1 1 1 Poxvirus D5 protein-like RNA_pol_Rpb2_6 PF00562.28 KFR07795.1 - 3.5e-128 428.0 0.0 1.2e-127 426.3 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KFR07795.1 - 1.3e-54 184.8 0.7 2.2e-54 184.1 0.7 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KFR07795.1 - 5.8e-35 119.6 0.7 1.7e-34 118.1 0.2 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KFR07795.1 - 7.1e-28 97.5 1.6 8e-28 97.4 0.5 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KFR07795.1 - 5.2e-27 93.9 1.1 1.4e-26 92.5 1.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KFR07795.1 - 3.6e-21 75.1 0.0 9e-21 73.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KFR07795.1 - 5.3e-10 39.7 5.5 6.4e-10 39.4 3.1 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 5 Fib_alpha PF08702.10 KFR07796.1 - 8e-07 29.3 44.3 0.035 14.3 3.8 5.5 1 1 5 6 6 6 4 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 KFR07796.1 - 1.6e-05 25.0 31.7 0.081 13.0 1.1 5.1 1 1 4 5 5 5 4 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 KFR07796.1 - 3.2e-05 23.0 51.8 0.016 14.1 11.0 4.7 1 1 4 5 5 5 5 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 KFR07796.1 - 0.00012 22.3 15.8 0.00012 22.3 15.8 5.0 1 1 3 5 5 5 1 Tropomyosin like DUF1664 PF07889.12 KFR07796.1 - 0.0012 18.9 43.5 0.7 9.9 8.2 7.3 1 1 8 9 9 9 3 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 KFR07796.1 - 0.0025 17.9 3.9 0.0025 17.9 3.9 5.4 2 2 3 5 5 5 2 TPR/MLP1/MLP2-like protein Tropomyosin PF00261.20 KFR07796.1 - 0.0034 16.8 46.8 0.012 15.0 5.7 5.1 1 1 4 5 5 5 2 Tropomyosin Filament PF00038.21 KFR07796.1 - 0.0044 16.7 45.5 0.15 11.6 19.8 3.9 1 1 2 3 3 3 2 Intermediate filament protein CENP-F_leu_zip PF10473.9 KFR07796.1 - 0.023 14.7 55.9 0.025 14.6 0.9 5.5 2 1 3 5 5 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EzrA PF06160.12 KFR07796.1 - 0.024 12.8 44.7 1.1 7.3 28.0 4.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA GAS PF13851.6 KFR07796.1 - 0.027 13.8 47.8 0.029 13.7 14.3 4.8 1 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding RPW8 PF05659.11 KFR07796.1 - 0.036 13.8 26.1 0.047 13.4 1.1 5.2 3 2 1 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Fez1 PF06818.15 KFR07796.1 - 0.048 14.1 43.3 0.85 10.0 1.5 3.8 1 1 3 4 4 4 0 Fez1 Syntaxin-6_N PF09177.11 KFR07796.1 - 0.083 13.5 41.3 0.33 11.5 6.9 5.7 2 2 3 5 5 5 0 Syntaxin 6, N-terminal KxDL PF10241.9 KFR07796.1 - 0.1 12.9 37.6 5 7.5 0.2 7.6 1 1 3 7 7 7 0 Uncharacterized conserved protein DUF3584 PF12128.8 KFR07796.1 - 0.2 9.1 41.1 0.096 10.2 26.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) E2R135 PF11570.8 KFR07796.1 - 0.24 11.7 14.9 0.19 12.1 2.9 4.2 3 1 1 4 4 4 0 Coiled-coil receptor-binding R-domain of colicin E2 DUF4172 PF13776.6 KFR07796.1 - 0.27 11.6 5.6 0.34 11.3 1.2 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4172) HMMR_N PF15905.5 KFR07796.1 - 0.27 10.6 53.7 0.19 11.2 2.3 4.3 1 1 3 4 4 4 0 Hyaluronan mediated motility receptor N-terminal TMPIT PF07851.13 KFR07796.1 - 0.4 9.9 38.4 0.44 9.7 11.0 4.6 1 1 3 5 5 5 0 TMPIT-like protein BLOC1_2 PF10046.9 KFR07796.1 - 0.62 10.4 46.3 0.58 10.5 0.4 7.3 2 2 4 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cob_adeno_trans PF01923.18 KFR07796.1 - 0.69 10.0 20.1 1.9 8.6 0.6 5.0 1 1 4 5 5 4 0 Cobalamin adenosyltransferase ADIP PF11559.8 KFR07796.1 - 0.71 9.9 44.4 0.59 10.2 6.7 5.7 1 1 3 6 6 6 0 Afadin- and alpha -actinin-Binding DUF4164 PF13747.6 KFR07796.1 - 1 9.7 31.5 1.2 9.4 0.7 6.7 3 2 3 6 6 6 0 Domain of unknown function (DUF4164) COG2 PF06148.11 KFR07796.1 - 1.1 9.4 42.0 0.27 11.3 1.0 6.4 1 1 6 7 7 7 0 COG (conserved oligomeric Golgi) complex component, COG2 Cytochrom_C_2 PF01322.20 KFR07796.1 - 1.1 10.2 16.6 1.1 10.2 3.5 4.8 2 2 2 4 4 4 0 Cytochrome C' NPV_P10 PF05531.12 KFR07796.1 - 1.1 9.8 37.1 0.22 12.0 2.6 7.1 2 2 3 5 5 4 0 Nucleopolyhedrovirus P10 protein Occludin_ELL PF07303.13 KFR07796.1 - 1.2 9.9 24.5 1.4 9.7 4.4 6.0 1 1 5 6 6 6 0 Occludin homology domain FlaC_arch PF05377.11 KFR07796.1 - 1.6 9.2 52.6 0.44 11.0 3.3 9.5 6 3 1 9 9 9 0 Flagella accessory protein C (FlaC) DUF812 PF05667.11 KFR07796.1 - 1.8 7.4 46.9 5.9 5.6 1.9 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF812) BRE1 PF08647.11 KFR07796.1 - 2.7 8.1 50.9 0.3 11.2 6.6 6.8 5 2 2 7 7 6 0 BRE1 E3 ubiquitin ligase DUF4200 PF13863.6 KFR07796.1 - 2.7 8.4 45.2 10 6.6 3.4 5.5 2 1 3 5 5 5 0 Domain of unknown function (DUF4200) YvrJ PF12841.7 KFR07796.1 - 3.4 7.3 17.5 2.7 7.6 0.0 5.8 7 0 0 7 7 7 0 YvrJ protein family CLZ PF16526.5 KFR07796.1 - 4.2 7.8 40.0 6.1 7.3 0.1 8.4 4 2 5 9 9 9 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PCRF PF03462.18 KFR07796.1 - 5.6 6.8 41.3 0.66 9.8 1.3 4.8 3 1 2 5 5 5 0 PCRF domain THOC7 PF05615.13 KFR07796.1 - 5.8 7.2 42.6 0.25 11.6 11.4 5.3 2 2 3 5 5 5 0 Tho complex subunit 7 DUF5082 PF16888.5 KFR07796.1 - 6.9 7.0 42.6 1.9 8.8 0.3 6.5 1 1 2 4 4 3 0 Domain of unknown function (DUF5082) Atg14 PF10186.9 KFR07796.1 - 7 5.6 35.8 1.6 7.7 5.8 4.6 1 1 4 5 5 5 0 Vacuolar sorting 38 and autophagy-related subunit 14 FUSC PF04632.12 KFR07796.1 - 7.4 5.0 5.6 9.4 4.6 0.7 2.6 1 1 2 3 3 3 0 Fusaric acid resistance protein family APG6_N PF17675.1 KFR07796.1 - 9.5 6.8 50.4 5.3 7.6 0.1 5.0 2 1 1 3 3 2 0 Apg6 coiled-coil region Pkinase PF00069.25 KFR07797.1 - 1.9e-77 260.2 0.0 2.8e-77 259.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR07797.1 - 5.6e-44 150.4 0.0 8.7e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR07797.1 - 3.6e-06 26.5 0.0 5.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFR07797.1 - 9.5e-06 25.1 0.3 2e-05 24.0 0.3 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFR07797.1 - 2.4e-05 23.5 1.6 3.9e-05 22.8 1.6 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KFR07797.1 - 3.9e-05 23.3 0.9 7e-05 22.5 0.9 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KFR07797.1 - 0.18 11.7 0.0 0.43 10.5 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 KFR07797.1 - 0.23 11.1 1.6 2 8.0 0.1 2.4 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RRM_1 PF00076.22 KFR07818.1 - 2.2e-39 133.1 0.3 1e-15 57.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFR07818.1 - 4e-06 26.9 0.3 0.016 15.3 0.1 3.7 3 1 0 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 KFR07818.1 - 0.00018 21.1 0.0 0.05 13.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KFR07818.1 - 0.0011 19.2 0.4 0.52 10.5 0.1 3.1 2 2 1 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter Limkain-b1 PF11608.8 KFR07818.1 - 0.019 15.0 0.1 0.75 9.9 0.0 2.9 3 0 0 3 3 3 0 Limkain b1 Nup35_RRM_2 PF14605.6 KFR07818.1 - 0.021 14.8 1.0 1.4 9.0 0.0 2.7 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif ERp29 PF07749.12 KFR07818.1 - 0.072 14.0 0.0 0.19 12.7 0.0 1.6 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Spo7_2_N PF15407.6 KFR07818.1 - 0.18 11.5 0.0 22 4.8 0.0 2.4 2 0 0 2 2 2 0 Sporulation protein family 7 RRM_occluded PF16842.5 KFR07818.1 - 0.19 11.6 0.0 23 4.9 0.0 2.9 3 0 0 3 3 3 0 Occluded RNA-recognition motif Methyltr_RsmB-F PF01189.17 KFR07820.1 - 2.7e-07 30.4 0.1 1.2e-06 28.3 0.1 2.0 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Tox-PL-2 PF15643.6 KFR07820.1 - 0.13 12.4 0.3 2.3 8.4 0.1 2.4 2 0 0 2 2 2 0 Papain fold toxin 2 Peptidase_C12 PF01088.21 KFR07821.1 - 1.7e-53 181.5 0.0 1.9e-53 181.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF4757 PF15949.5 KFR07822.1 - 7.8e-65 218.5 10.2 7.8e-65 218.5 10.2 3.7 2 1 1 3 3 3 1 Domain of unknown function (DUF4757) LIM PF00412.22 KFR07822.1 - 1.8e-07 31.3 0.3 4.3e-07 30.1 0.3 1.7 1 0 0 1 1 1 1 LIM domain Homeodomain PF00046.29 KFR07823.1 - 5.9e-14 51.7 0.5 9.2e-14 51.0 0.5 1.3 1 0 0 1 1 1 1 Homeodomain Myb_DNA-bind_3 PF12776.7 KFR07823.1 - 0.026 15.5 0.0 1.5 9.9 0.0 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain UPF0121 PF03661.13 KFR07824.1 - 9.8e-94 313.3 17.9 1.1e-93 313.1 17.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Cation_efflux PF01545.21 KFR07825.1 - 1.6e-31 109.6 7.7 2e-31 109.3 7.7 1.1 1 0 0 1 1 1 1 Cation efflux family XPA_C PF05181.12 KFR07825.1 - 0.00014 21.7 0.0 0.00034 20.5 0.0 1.7 1 0 0 1 1 1 1 XPA protein C-terminus ZT_dimer PF16916.5 KFR07825.1 - 0.0028 17.7 1.1 0.099 12.8 0.1 3.0 2 1 1 3 3 3 1 Dimerisation domain of Zinc Transporter Ion_trans_N PF08412.10 KFR07825.1 - 0.032 13.8 0.0 0.078 12.6 0.0 1.6 1 0 0 1 1 1 0 Ion transport protein N-terminal Peptidase_M30 PF10460.9 KFR07825.1 - 0.04 12.9 0.1 0.15 11.0 0.0 1.8 2 0 0 2 2 2 0 Peptidase M30 P2 PF07194.11 KFR07825.1 - 0.064 13.3 0.1 0.3 11.2 0.2 2.1 2 0 0 2 2 2 0 P2 response regulator binding domain Deltameth_res PF16020.5 KFR07825.1 - 0.095 12.6 0.4 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 Deltamethrin resistance BEN PF10523.9 KFR07826.1 - 2.2e-15 56.6 0.0 4.9e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 BEN domain bZIP_1 PF00170.21 KFR07826.1 - 0.0048 17.0 0.2 0.013 15.5 0.2 1.8 1 0 0 1 1 1 1 bZIP transcription factor Uds1 PF15456.6 KFR07826.1 - 0.015 15.5 0.1 0.028 14.6 0.1 1.4 1 0 0 1 1 1 0 Up-regulated During Septation Cep57_CLD_2 PF14197.6 KFR07826.1 - 0.026 14.6 0.6 0.16 12.1 0.2 2.1 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Shugoshin_N PF07558.11 KFR07826.1 - 0.027 14.4 1.6 0.027 14.4 1.6 1.9 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region NYD-SP28_assoc PF14775.6 KFR07826.1 - 0.043 13.9 1.9 0.12 12.5 1.9 1.8 1 0 0 1 1 1 0 Sperm tail C-terminal domain bZIP_2 PF07716.15 KFR07826.1 - 0.043 13.9 3.9 0.097 12.8 3.9 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Herpes_BLRF2 PF05812.12 KFR07826.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Shisa PF13908.6 KFR07827.1 - 8.9e-22 78.3 0.6 1e-21 78.0 0.6 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator PhoLip_ATPase_C PF16212.5 KFR07828.1 - 2.4e-86 289.6 20.0 2.4e-86 289.6 20.0 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFR07828.1 - 8.1e-26 89.5 4.3 2.3e-25 88.1 4.3 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFR07828.1 - 2.3e-13 50.9 0.0 1.9e-05 25.1 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFR07828.1 - 1.3e-12 47.6 0.0 1.7e-11 44.1 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFR07828.1 - 3.1e-11 43.1 0.0 1.3e-10 41.1 0.0 2.1 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFR07828.1 - 0.00019 21.3 0.3 0.012 15.4 0.1 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Glutaredoxin PF00462.24 KFR07829.1 - 4.7e-09 36.3 0.1 2.2e-08 34.2 0.1 2.1 2 0 0 2 2 2 1 Glutaredoxin BTB_2 PF02214.22 KFR07830.1 - 2.1e-16 60.0 0.0 2.4e-15 56.7 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 KFR07830.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain GTP_EFTU PF00009.27 KFR07832.1 - 4.3e-53 179.8 0.1 6.3e-53 179.2 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KFR07832.1 - 6.7e-47 158.1 0.8 2.2e-46 156.4 0.5 2.1 2 0 0 2 2 2 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KFR07832.1 - 8e-21 73.9 0.0 3.1e-20 72.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFR07832.1 - 5.1e-07 30.0 0.1 1.5e-06 28.5 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.22 KFR07832.1 - 2.5e-06 27.2 0.0 4.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Ras family RF3_C PF16658.5 KFR07832.1 - 9.2e-06 25.5 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 KFR07832.1 - 1.1e-05 25.5 0.0 2.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 KFR07832.1 - 2.3e-05 24.4 0.0 7.8e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 KFR07832.1 - 0.0036 16.8 0.0 0.0091 15.4 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 KFR07832.1 - 0.0042 17.1 0.5 0.01 15.8 0.1 1.9 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 KFR07832.1 - 0.034 13.7 0.3 0.11 12.1 0.3 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Glucosamine_iso PF01182.20 KFR07833.1 - 2e-20 73.6 0.0 2.9e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Neur_chan_memb PF02932.16 KFR07834.1 - 3.7e-40 138.5 3.1 1.6e-35 123.3 0.7 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFR07834.1 - 4.4e-37 127.6 1.8 5.6e-37 127.3 1.8 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.23 KFR07835.1 - 6.5e-50 169.6 0.0 9.7e-50 169.0 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFR07835.1 - 5.4e-38 131.4 7.8 7.7e-31 108.0 5.6 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region CytochromB561_N PF09786.9 KFR07835.1 - 0.067 12.2 2.0 0.092 11.7 2.0 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF5522 PF17653.1 KFR07835.1 - 0.11 12.5 0.1 0.32 11.0 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5522) Neur_chan_LBD PF02931.23 KFR07836.1 - 5e-43 147.1 0.0 7.3e-43 146.5 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFR07836.1 - 8.8e-43 147.1 0.7 1.5e-42 146.4 0.7 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF3695 PF12494.8 KFR07836.1 - 0.017 15.0 0.1 8.6 6.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3695) DUF4396 PF14342.6 KFR07836.1 - 0.13 12.7 7.6 1.2 9.5 2.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4396) Neur_chan_memb PF02932.16 KFR07837.1 - 2.4e-48 165.3 0.3 7.7e-48 163.6 0.3 1.7 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFR07837.1 - 1.6e-37 129.1 0.1 2.5e-37 128.4 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain COMM_domain PF07258.14 KFR07838.1 - 1.5e-16 60.3 1.6 2.3e-16 59.6 1.6 1.3 1 0 0 1 1 1 1 COMM domain HOIP-UBA PF16678.5 KFR07838.1 - 0.0017 18.4 0.1 0.0028 17.7 0.1 1.5 1 0 0 1 1 1 1 HOIP UBA domain pair PhoLip_ATPase_C PF16212.5 KFR07839.1 - 4.6e-75 252.6 26.7 4.6e-75 252.6 26.7 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFR07839.1 - 4.2e-23 80.8 2.6 4.2e-23 80.8 2.6 2.1 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFR07839.1 - 3.3e-12 47.1 0.0 3.3e-06 27.5 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFR07839.1 - 2.1e-10 40.5 0.0 1.5e-09 37.8 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFR07839.1 - 0.00088 18.8 0.1 0.0045 16.5 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFR07839.1 - 0.003 17.3 2.1 0.0087 15.8 0.1 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Trypsin PF00089.26 KFR07840.1 - 9.6e-64 215.2 0.1 2.2e-63 214.0 0.1 1.7 1 0 0 1 1 1 1 Trypsin Ldl_recept_a PF00057.18 KFR07840.1 - 1.3e-59 198.1 150.8 1.1e-10 41.5 7.1 9.4 9 1 0 9 9 9 7 Low-density lipoprotein receptor domain class A Fz PF01392.22 KFR07840.1 - 2.7e-44 150.3 17.4 2.2e-25 89.4 5.4 5.6 4 2 1 5 5 5 2 Fz domain SRCR_2 PF15494.6 KFR07840.1 - 1.6e-08 35.0 1.4 1.6e-08 35.0 1.4 2.7 3 0 0 3 3 3 1 Scavenger receptor cysteine-rich domain Trypsin_2 PF13365.6 KFR07840.1 - 2.2e-08 35.1 0.0 3.9e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFR07840.1 - 0.022 15.1 0.3 0.068 13.5 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) zf-NF-X1 PF01422.17 KFR07841.1 - 1.2e-13 50.8 101.8 6.3e-06 26.1 14.9 18.0 19 0 0 19 19 19 9 NF-X1 type zinc finger Casc1_N PF15927.5 KFR07841.1 - 0.11 12.2 8.2 0.25 11.0 8.2 1.5 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Ion_trans PF00520.31 KFR07842.1 - 1.4e-33 116.1 11.9 2e-33 115.7 11.9 1.2 1 0 0 1 1 1 1 Ion transport protein CLZ PF16526.5 KFR07842.1 - 1.3e-27 95.9 7.6 1.6e-27 95.7 6.3 1.9 2 0 0 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels cNMP_binding PF00027.29 KFR07842.1 - 2e-19 69.4 0.0 3.3e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KFR07842.1 - 0.0048 16.8 3.2 0.039 13.9 4.1 2.2 2 0 0 2 2 2 1 Ion channel GrpE PF01025.19 KFR07842.1 - 0.13 11.9 1.6 0.3 10.7 1.6 1.5 1 0 0 1 1 1 0 GrpE SlyX PF04102.12 KFR07842.1 - 0.54 10.9 3.3 1.4 9.6 1.9 2.2 2 0 0 2 2 2 0 SlyX OmpH PF03938.14 KFR07842.1 - 5 7.5 9.1 15 5.9 7.4 2.5 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Occludin_ELL PF07303.13 KFR07842.1 - 6.5 7.5 8.1 5.4 7.8 0.1 2.8 3 0 0 3 3 3 0 Occludin homology domain Mg_trans_NIPA PF05653.14 KFR07843.1 - 7e-134 445.6 14.6 8.4e-134 445.3 14.6 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KFR07843.1 - 1.2e-08 35.2 5.4 1.2e-08 35.2 5.4 4.5 3 1 0 3 3 3 1 EamA-like transporter family Deltameth_res PF16020.5 KFR07843.1 - 0.089 12.7 3.9 4.1 7.3 0.1 3.2 2 1 1 3 3 3 0 Deltamethrin resistance DUF5392 PF17370.2 KFR07843.1 - 0.3 11.2 1.5 0.57 10.3 1.2 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5392) Pkinase_Tyr PF07714.17 KFR07844.1 - 3.5e-96 321.4 0.4 4.2e-96 321.2 0.4 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR07844.1 - 8.1e-49 166.4 0.1 1e-48 166.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFR07844.1 - 5.4e-05 23.2 0.3 0.00014 21.9 0.3 1.7 1 0 0 1 1 1 1 SH2 domain Haspin_kinase PF12330.8 KFR07844.1 - 0.0068 15.4 0.0 0.0085 15.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFR07844.1 - 0.014 15.3 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KFR07844.1 - 0.026 13.9 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KFR07845.1 - 9.4e-95 316.8 0.1 1.3e-94 316.3 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR07845.1 - 5.4e-46 157.1 0.0 8.5e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFR07845.1 - 5.7e-19 68.0 0.1 1.5e-18 66.6 0.1 1.8 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFR07845.1 - 5.7e-16 57.9 0.2 2.3e-15 55.9 0.2 2.1 2 0 0 2 2 2 1 SH3 domain PH PF00169.29 KFR07845.1 - 4.7e-15 56.0 0.6 1.1e-14 54.8 0.2 1.9 2 0 0 2 2 2 1 PH domain BTK PF00779.19 KFR07845.1 - 1.1e-12 47.5 1.9 3e-12 46.1 1.9 1.8 1 0 0 1 1 1 1 BTK motif SH3_9 PF14604.6 KFR07845.1 - 1.4e-09 37.7 0.1 2.8e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFR07845.1 - 4.3e-07 29.5 0.0 1.1e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 KFR07845.1 - 0.0026 18.1 0.0 0.01 16.3 0.0 2.0 1 0 0 1 1 1 1 Helically-extended SH3 domain SH3_3 PF08239.11 KFR07845.1 - 0.02 15.2 1.9 0.32 11.3 1.0 2.5 2 0 0 2 2 2 0 Bacterial SH3 domain SH3_10 PF17902.1 KFR07845.1 - 0.025 14.6 0.0 0.069 13.2 0.0 1.7 1 0 0 1 1 1 0 SH3 domain Kinase-like PF14531.6 KFR07845.1 - 0.079 12.3 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 Kinase-like SLAIN PF15301.6 KFR07846.1 - 1e-168 562.1 40.9 1.1e-168 562.0 40.9 1.0 1 0 0 1 1 1 1 SLAIN motif-containing family SBF PF01758.16 KFR07847.1 - 9.2e-11 41.8 7.4 9.2e-11 41.8 7.4 2.1 3 0 0 3 3 3 1 Sodium Bile acid symporter family DUF3392 PF11872.8 KFR07847.1 - 0.085 13.1 9.1 2.7 8.3 5.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3392) MOR2-PAG1_N PF14222.6 KFR07848.1 - 1.3e-174 582.2 4.7 2.2e-174 581.5 4.7 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KFR07848.1 - 9e-75 251.8 5.0 9e-75 251.8 5.0 3.6 4 0 0 4 4 4 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KFR07848.1 - 5.6e-36 123.7 13.9 2.4e-14 52.0 0.2 6.1 6 0 0 6 6 6 6 Cell morphogenesis central region OCIA PF07051.11 KFR07849.1 - 1e-29 102.3 0.1 1.7e-29 101.7 0.1 1.3 1 0 0 1 1 1 1 Ovarian carcinoma immunoreactive antigen (OCIA) ANAPC1 PF12859.7 KFR07849.1 - 0.092 13.3 3.2 0.12 12.9 3.2 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 OCIA PF07051.11 KFR07850.1 - 7.4e-31 106.0 0.2 7.9e-31 105.9 0.2 1.0 1 0 0 1 1 1 1 Ovarian carcinoma immunoreactive antigen (OCIA) GLTT PF01744.20 KFR07850.1 - 0.042 13.6 0.1 0.069 12.9 0.1 1.4 1 0 0 1 1 1 0 GLTT repeat (6 copies) HCV_NS4a PF01006.20 KFR07851.1 - 0.054 13.3 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a Cullin_binding PF03556.15 KFR07852.1 - 2.2e-31 108.8 0.6 3.9e-31 108.0 0.6 1.4 1 0 0 1 1 1 1 Cullin binding LRR_8 PF13855.6 KFR07853.1 - 1.1e-23 82.7 22.9 7.4e-10 38.5 0.4 3.9 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KFR07853.1 - 2.2e-16 59.7 24.8 1.4e-07 31.7 6.2 4.6 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFR07853.1 - 3.5e-08 33.5 2.9 3.7e-07 30.2 0.0 2.6 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFR07853.1 - 1e-07 31.5 16.1 0.55 11.0 0.9 6.7 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_9 PF14580.6 KFR07853.1 - 2.2e-05 24.0 8.6 0.0073 15.8 3.1 2.4 2 1 1 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 KFR07853.1 - 0.0024 17.8 22.0 9.6 6.6 0.3 6.9 7 0 0 7 7 7 2 Leucine Rich repeat PI-TkoII_IV PF18714.1 KFR07853.1 - 0.072 12.5 0.0 0.16 11.4 0.0 1.5 1 1 0 1 1 1 0 DNA polymerase II intein Domain IV DUF688 PF05097.12 KFR07853.1 - 0.28 10.3 0.3 0.54 9.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF688) Sarcoglycan_1 PF04790.13 KFR07854.1 - 3.7e-63 213.3 0.2 4.7e-63 213.0 0.2 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein Sec62 PF03839.16 KFR07854.1 - 3.3 7.1 4.3 6.8 6.1 4.3 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 MIEAP PF16026.5 KFR07855.1 - 1.3e-60 205.0 0.0 1.5e-60 204.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondria-eating protein Phage_min_tail PF05939.13 KFR07855.1 - 0.099 13.0 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Phage minor tail protein UCH PF00443.29 KFR07856.1 - 2.3e-60 204.2 6.4 2.7e-60 204.0 6.4 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFR07856.1 - 7.3e-30 104.6 10.8 1e-29 104.2 10.8 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KFR07856.1 - 5.4e-05 22.8 14.8 0.00024 20.7 12.3 2.1 2 0 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF3399 PF11879.8 KFR07856.1 - 0.4 11.0 8.7 0.84 10.0 8.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3399) NapB PF03892.14 KFR07856.1 - 3.1 7.8 7.6 7.8 6.5 7.6 1.7 1 1 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) Ras PF00071.22 KFR07857.1 - 1.8e-20 73.2 0.0 2.3e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 KFR07857.1 - 0.0086 16.0 0.0 0.042 13.8 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KFR07857.1 - 0.016 15.3 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF3322 PF11795.8 KFR07859.1 - 0.13 12.3 0.1 0.95 9.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) IZUMO PF15005.6 KFR07859.1 - 0.15 12.6 0.6 0.39 11.2 0.2 1.9 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated Fip1 PF05182.13 KFR07860.1 - 4.4e-25 86.9 2.1 4.4e-25 86.9 2.1 1.8 2 0 0 2 2 2 1 Fip1 motif PDZ PF00595.24 KFR07861.1 - 7.9e-60 199.2 2.5 2.4e-16 59.9 0.0 4.3 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 KFR07861.1 - 1.8e-30 104.5 1.4 2.1e-07 30.7 0.0 4.4 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 KFR07861.1 - 1.2e-15 57.6 0.1 0.0051 17.1 0.0 4.3 4 0 0 4 4 4 4 PDZ domain zf-C3HC4_2 PF13923.6 KFR07861.1 - 2.3e-06 27.3 8.4 8.9e-06 25.5 8.4 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFR07861.1 - 2.8e-06 27.6 5.7 1.5e-05 25.3 5.7 2.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFR07861.1 - 3.4e-06 26.8 6.5 1.2e-05 25.1 6.5 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFR07861.1 - 3.5e-06 26.9 7.4 1.3e-05 25.1 7.4 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFR07861.1 - 2.1e-05 24.4 4.9 9.1e-05 22.3 4.9 2.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFR07861.1 - 0.00024 21.2 6.8 0.00097 19.3 6.8 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KFR07861.1 - 0.00029 20.6 2.1 0.00029 20.6 2.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFR07861.1 - 0.0017 18.6 3.2 0.0077 16.5 3.2 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain DZR PF12773.7 KFR07861.1 - 0.14 12.2 2.7 0.78 9.8 2.7 2.3 1 1 0 1 1 1 0 Double zinc ribbon Pkinase_Tyr PF07714.17 KFR07862.1 - 4.8e-86 288.2 0.0 9.4e-86 287.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR07862.1 - 4.8e-39 134.3 0.0 1.1e-23 84.0 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.6 KFR07862.1 - 1.7e-24 86.2 8.1 7.7e-07 29.6 0.1 5.8 6 0 0 6 6 6 4 Immunoglobulin domain I-set PF07679.16 KFR07862.1 - 1.4e-19 70.0 9.8 5.2e-08 32.8 0.4 5.0 5 1 0 5 5 5 3 Immunoglobulin I-set domain ig PF00047.25 KFR07862.1 - 2.1e-18 66.2 10.7 0.0006 19.9 0.0 5.9 6 0 0 6 6 6 5 Immunoglobulin domain Ig_2 PF13895.6 KFR07862.1 - 2.6e-13 50.1 8.6 3.9e-05 23.9 0.1 5.9 5 2 0 5 5 5 3 Immunoglobulin domain V-set PF07686.17 KFR07862.1 - 5e-05 23.4 6.8 0.031 14.4 0.2 5.6 5 2 0 5 5 5 1 Immunoglobulin V-set domain Herpes_gE PF02480.16 KFR07862.1 - 0.0017 17.2 1.3 0.47 9.1 0.1 3.4 3 1 0 4 4 4 1 Alphaherpesvirus glycoprotein E Gypsy PF07253.11 KFR07862.1 - 0.0097 14.5 0.1 1.4 7.4 0.0 2.3 2 0 0 2 2 2 2 Gypsy protein C2-set_2 PF08205.12 KFR07862.1 - 0.15 12.2 3.5 7.9 6.6 0.0 4.4 5 0 0 5 5 5 0 CD80-like C2-set immunoglobulin domain Adeno_E3_CR1 PF02440.15 KFR07862.1 - 0.51 10.2 3.5 3 7.7 0.3 3.2 3 1 0 3 3 3 0 Adenovirus E3 region protein CR1 Pkinase_Tyr PF07714.17 KFR07863.1 - 4.4e-104 347.3 0.0 6.5e-104 346.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR07863.1 - 2.7e-42 145.0 0.0 2.5e-30 105.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.6 KFR07863.1 - 9.6e-31 106.2 7.4 2.6e-09 37.6 0.1 5.5 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 KFR07863.1 - 3.5e-25 87.9 2.9 1.2e-09 38.1 0.1 5.7 5 1 1 6 6 6 4 Immunoglobulin I-set domain ig PF00047.25 KFR07863.1 - 2.2e-18 66.2 10.9 4.5e-11 42.8 0.2 5.5 5 0 0 5 5 5 4 Immunoglobulin domain Ig_2 PF13895.6 KFR07863.1 - 3.6e-12 46.4 6.6 0.00028 21.2 0.1 5.0 5 0 0 5 5 5 3 Immunoglobulin domain V-set PF07686.17 KFR07863.1 - 1e-08 35.3 8.0 0.32 11.2 0.1 6.9 5 2 1 6 6 6 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFR07863.1 - 6e-06 26.2 0.1 0.089 12.9 0.0 2.9 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFR07863.1 - 0.00058 19.4 0.6 0.55 9.8 0.0 3.5 3 0 0 3 3 3 1 Immunoglobulin domain Ig_5 PF16681.5 KFR07863.1 - 0.0012 19.2 0.5 2.2 8.7 0.1 3.7 3 0 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain APH PF01636.23 KFR07863.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family HTH_38 PF13936.6 KFR07863.1 - 0.16 11.8 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Adeno_E3_CR1 PF02440.15 KFR07863.1 - 2.7 7.8 5.4 6.1 6.7 0.1 3.9 4 1 0 4 4 4 0 Adenovirus E3 region protein CR1 Pkinase_Tyr PF07714.17 KFR07864.1 - 2.4e-106 354.8 0.0 3.2e-106 354.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR07864.1 - 4.9e-43 147.4 0.0 2.7e-30 105.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.6 KFR07864.1 - 1.8e-25 89.4 4.8 4.8e-15 55.9 0.1 3.6 4 0 0 4 4 3 2 Immunoglobulin domain I-set PF07679.16 KFR07864.1 - 1.8e-24 85.6 0.1 1.5e-15 57.0 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain VEGFR-2_TMD PF17988.1 KFR07864.1 - 1.4e-18 66.0 4.6 2.7e-18 65.1 4.6 1.5 1 0 0 1 1 1 1 VEGFR-2 Transmembrane domain Ig_2 PF13895.6 KFR07864.1 - 5.9e-18 65.0 2.7 1.5e-10 41.2 0.0 3.7 3 1 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFR07864.1 - 1.6e-17 63.4 0.9 2.6e-10 40.3 0.1 3.9 4 1 0 4 4 4 2 Immunoglobulin domain V-set PF07686.17 KFR07864.1 - 2e-07 31.1 1.0 0.43 10.8 0.0 4.2 3 1 1 4 4 4 2 Immunoglobulin V-set domain Izumo-Ig PF16706.5 KFR07864.1 - 1.8e-05 24.7 0.5 1 9.5 0.0 3.7 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 KFR07864.1 - 0.00052 20.0 0.0 0.0018 18.3 0.0 2.0 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFR07864.1 - 0.007 16.6 0.7 1.2 9.4 0.0 3.2 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFR07864.1 - 0.016 14.8 0.1 10 5.8 0.0 2.7 2 0 0 2 2 2 0 Immunoglobulin domain Haspin_kinase PF12330.8 KFR07864.1 - 0.022 13.7 1.0 0.036 13.0 0.1 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Adeno_E3_CR1 PF02440.15 KFR07864.1 - 0.42 10.4 2.0 6.6 6.6 0.3 2.8 2 2 0 2 2 2 0 Adenovirus E3 region protein CR1 Ehrlichia_rpt PF09528.10 KFR07864.1 - 1.3 8.5 3.2 0.99 8.9 0.5 2.1 2 0 0 2 2 2 0 Ehrlichia tandem repeat (Ehrlichia_rpt) Steroid_dh PF02544.16 KFR07865.1 - 3.2e-22 79.1 6.8 5.6e-22 78.3 6.4 1.7 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase FB_lectin PF07367.11 KFR07865.1 - 0.028 14.4 0.1 0.05 13.5 0.1 1.3 1 0 0 1 1 1 0 Fungal fruit body lectin SPC25 PF06703.11 KFR07865.1 - 0.059 13.1 2.2 1.1 9.0 0.8 2.4 2 1 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) UPF0016 PF01169.19 KFR07866.1 - 4.4e-45 151.9 19.7 4.7e-23 81.3 3.3 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 PAS_11 PF14598.6 KFR07867.1 - 2.3e-20 72.8 0.0 2.3e-20 72.8 0.0 4.2 3 1 0 4 4 4 1 PAS domain PAS_3 PF08447.12 KFR07867.1 - 3e-17 62.7 1.3 1.3e-15 57.4 0.1 3.0 3 0 0 3 3 3 1 PAS fold HLH PF00010.26 KFR07867.1 - 5.8e-11 42.2 0.9 1.4e-10 41.0 0.9 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS PF00989.25 KFR07867.1 - 3.5e-07 30.2 7.5 1.6e-06 28.1 0.0 3.9 5 0 0 5 5 5 1 PAS fold PAS_9 PF13426.7 KFR07867.1 - 0.00067 19.9 0.0 0.0037 17.5 0.0 2.4 2 0 0 2 2 2 1 PAS domain Phosducin PF02114.16 KFR07868.1 - 4.5e-12 45.5 0.3 5.9e-12 45.1 0.3 1.1 1 0 0 1 1 1 1 Phosducin Sec3_C PF09763.9 KFR07870.1 - 9.4e-179 596.1 27.3 1.2e-178 595.8 27.3 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KFR07870.1 - 1.3e-26 92.5 2.2 5e-26 90.6 2.2 2.0 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH FlaC_arch PF05377.11 KFR07870.1 - 0.06 13.8 5.2 0.27 11.6 2.3 3.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) YabA PF06156.13 KFR07870.1 - 1.1 9.9 8.0 1 10.1 1.8 3.6 2 1 0 2 2 2 0 Initiation control protein YabA Csm2_III-A PF03750.13 KFR07870.1 - 1.1 10.1 6.7 0.89 10.4 2.0 3.2 2 0 0 2 2 2 0 Csm2 Type III-A KASH_CCD PF14662.6 KFR07871.1 - 0.00053 19.9 10.0 0.00053 19.9 10.0 9.5 3 2 3 8 8 8 2 Coiled-coil region of CCDC155 or KASH BLOC1_2 PF10046.9 KFR07871.1 - 0.0052 17.0 6.8 0.0052 17.0 6.8 13.4 8 5 6 15 15 15 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.11 KFR07871.1 - 0.01 16.1 162.4 0.18 12.0 12.4 10.2 4 2 4 10 10 10 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 KFR07871.1 - 3.2 8.1 149.0 0.023 15.1 21.2 8.7 2 1 6 8 8 8 0 Fez1 DUF4592 PF15262.6 KFR07872.1 - 9.9e-40 136.3 3.5 9.9e-40 136.3 3.5 6.8 5 2 0 5 5 5 1 Domain of unknown function (DUF4592) AMP-binding PF00501.28 KFR07873.1 - 1e-43 149.6 0.0 1.7e-43 148.8 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme PQQ_3 PF13570.6 KFR07873.1 - 1.3e-34 117.8 0.0 7.8e-06 26.2 0.1 9.2 9 0 0 9 9 9 6 PQQ-like domain PQQ PF01011.21 KFR07873.1 - 6.4e-25 85.9 5.7 0.0024 17.7 0.0 8.6 8 0 0 8 8 8 7 PQQ enzyme repeat PQQ_2 PF13360.6 KFR07873.1 - 5.8e-19 68.6 0.0 3.7e-11 43.1 0.0 3.0 2 1 1 3 3 3 2 PQQ-like domain AMP-binding_C PF13193.6 KFR07873.1 - 5.7e-06 27.2 0.0 1.4e-05 26.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ANAPC4_WD40 PF12894.7 KFR07873.1 - 0.0028 17.9 0.2 5.2 7.4 0.0 4.5 6 0 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain PP-binding PF00550.25 KFR07873.1 - 0.0069 16.7 0.0 0.018 15.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Meleagrin PF08189.11 KFR07873.1 - 0.018 14.7 0.6 0.1 12.3 0.6 2.3 1 0 0 1 1 1 0 Meleagrin/Cygnin family GATase_6 PF13522.6 KFR07874.1 - 5.8e-15 55.7 0.0 1.1e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KFR07874.1 - 7.5e-13 48.5 0.0 1.3e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KFR07874.1 - 1.8e-08 34.1 0.0 2.8e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KFR07874.1 - 1.4e-06 27.5 0.0 2.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 KFR07874.1 - 0.0059 15.4 0.0 0.0093 14.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II UPRTase PF14681.6 KFR07874.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KFR07874.1 - 0.2 11.2 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase Myb_DNA-bind_4 PF13837.6 KFR07875.1 - 5.9e-19 68.2 1.6 7.5e-19 67.9 1.6 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 KFR07875.1 - 0.0017 18.5 1.8 0.0032 17.6 1.8 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFR07875.1 - 0.02 15.1 2.0 0.058 13.6 2.0 1.7 1 1 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 KFR07875.1 - 0.027 14.6 3.7 0.14 12.2 3.7 2.0 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 KFR07875.1 - 0.12 13.3 1.1 0.19 12.8 1.1 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain SAICAR_synt PF01259.18 KFR07876.1 - 7.9e-55 186.2 0.1 1.1e-54 185.7 0.1 1.2 1 0 0 1 1 1 1 SAICAR synthetase AIRC PF00731.20 KFR07876.1 - 2.7e-39 134.1 0.0 4.6e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 AIR carboxylase LON_substr_bdg PF02190.16 KFR07877.1 - 2.2e-26 93.0 0.0 4.4e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KFR07877.1 - 2.2e-09 37.0 14.3 5.1e-09 35.8 14.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFR07877.1 - 3.4e-09 36.4 8.3 8.3e-09 35.2 8.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFR07877.1 - 2.5e-07 30.4 12.4 6.6e-07 29.1 12.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFR07877.1 - 6e-07 29.7 13.1 1.6e-06 28.3 13.1 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFR07877.1 - 8.7e-07 28.9 10.8 8.7e-07 28.9 10.8 2.8 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFR07877.1 - 7.9e-06 25.7 12.2 1.7e-05 24.7 12.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFR07877.1 - 1.8e-05 24.5 9.9 3.7e-05 23.5 9.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFR07877.1 - 5.7e-05 23.2 11.9 0.00018 21.6 11.9 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KFR07877.1 - 7.4e-05 22.8 6.5 0.00017 21.7 6.5 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 TPR_2 PF07719.17 KFR07877.1 - 0.00024 21.0 0.0 0.088 13.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat U-box PF04564.15 KFR07877.1 - 0.0013 18.9 0.0 0.0031 17.7 0.0 1.6 1 0 0 1 1 1 1 U-box domain NARP1 PF12569.8 KFR07877.1 - 0.011 14.7 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 zf-rbx1 PF12678.7 KFR07877.1 - 0.014 15.7 9.2 0.034 14.4 9.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain TPR_11 PF13414.6 KFR07877.1 - 0.021 14.5 0.0 0.067 12.9 0.0 1.9 2 0 0 2 2 2 0 TPR repeat zf-RING_4 PF14570.6 KFR07877.1 - 0.029 14.2 5.0 0.083 12.7 5.0 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TPR_1 PF00515.28 KFR07877.1 - 0.033 14.0 0.2 16 5.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-RING_6 PF14835.6 KFR07877.1 - 0.071 13.0 6.6 0.17 11.7 6.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_5 PF17121.5 KFR07877.1 - 0.65 9.9 5.9 1.8 8.5 5.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 KFR07877.1 - 0.7 9.8 4.2 1.8 8.5 4.2 1.7 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Methyltransf_11 PF08241.12 KFR07878.1 - 1.3e-14 54.5 0.0 3e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFR07878.1 - 1.7e-13 51.1 0.0 4.1e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFR07878.1 - 1.8e-07 31.1 0.1 1.8e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFR07878.1 - 2.4e-07 30.7 0.1 7.2e-07 29.1 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFR07878.1 - 6e-06 26.9 0.1 2e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 KFR07878.1 - 7.5e-06 26.0 0.0 1.8e-05 24.7 0.1 1.7 2 0 0 2 2 2 1 Hypothetical methyltransferase Ubie_methyltran PF01209.18 KFR07878.1 - 1.2e-05 24.8 0.0 4.8e-05 22.8 0.0 2.0 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KFR07878.1 - 8.1e-05 22.0 0.1 0.0046 16.3 0.2 2.7 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KFR07878.1 - 0.016 14.2 0.0 4.3 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) DUF4518 PF15008.6 KFR07878.1 - 0.1 11.8 0.4 0.16 11.2 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) START PF01852.19 KFR07879.1 - 3.7e-49 167.0 0.1 3.7e-49 167.0 0.1 1.6 2 0 0 2 2 2 1 START domain RhoGAP PF00620.27 KFR07879.1 - 1.2e-41 142.0 0.7 5.5e-41 139.9 0.9 1.9 2 0 0 2 2 2 1 RhoGAP domain Sarcoglycan_1 PF04790.13 KFR07881.1 - 1.2e-86 290.2 0.0 1.4e-86 290.0 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2345 PF10106.9 KFR07881.1 - 3.6e-05 23.7 0.0 0.0012 18.7 0.0 2.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2345) ORF_2_N PF18492.1 KFR07881.1 - 0.15 12.2 0.1 7.7 6.7 0.1 2.2 2 0 0 2 2 2 0 Open reading frame 2 N-terminal domain OST3_OST6 PF04756.13 KFR07883.1 - 1.7e-93 313.2 0.1 1.9e-93 313.1 0.1 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 KFR07883.1 - 2.1e-05 24.5 0.0 3.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Gram_pos_anchor PF00746.21 KFR07883.1 - 0.045 13.7 0.4 0.079 12.9 0.4 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif YhhN PF07947.14 KFR07883.1 - 0.07 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 YhhN family FGF PF00167.18 KFR07885.1 - 4.1e-33 114.2 0.1 4.6e-33 114.0 0.1 1.0 1 0 0 1 1 1 1 Fibroblast growth factor EF-hand_8 PF13833.6 KFR07886.1 - 1.4e-16 60.1 7.4 1.5e-07 31.2 0.0 6.0 6 1 0 6 6 6 2 EF-hand domain pair EF-hand_7 PF13499.6 KFR07886.1 - 1.7e-13 50.8 13.7 1.6e-05 25.3 1.7 5.5 3 3 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KFR07886.1 - 4.9e-11 41.6 9.7 0.00025 20.7 0.4 6.2 8 0 0 8 8 8 2 EF-hand domain EF-hand_1 PF00036.32 KFR07886.1 - 2.8e-09 35.8 21.3 0.0001 21.6 0.7 6.9 8 0 0 8 8 8 2 EF hand EF-hand_4 PF12763.7 KFR07886.1 - 0.0057 16.6 0.7 0.06 13.3 0.1 2.8 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 KFR07886.1 - 0.042 13.4 11.3 2.9 7.6 0.2 5.2 6 0 0 6 6 6 0 EF hand DUF4734 PF15881.5 KFR07886.1 - 0.14 12.3 1.7 22 5.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4734) SinI PF08671.10 KFR07886.1 - 0.26 11.1 1.8 0.61 9.9 1.8 1.7 1 0 0 1 1 1 0 Anti-repressor SinI DHHC PF01529.20 KFR07887.1 - 8.6e-36 123.0 14.2 8.6e-36 123.0 14.2 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Spt4 PF06093.13 KFR07887.1 - 1 9.5 6.8 1.8 8.7 6.8 1.4 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger CAF1 PF04857.20 KFR07888.1 - 1.2e-22 80.5 0.6 1.7e-11 43.8 0.1 2.5 1 1 1 2 2 2 2 CAF1 family ribonuclease Mod_r PF07200.13 KFR07889.1 - 5.8e-39 133.5 15.9 7.7e-39 133.1 15.9 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein UEV PF05743.13 KFR07889.1 - 0.0006 19.7 4.7 0.004 17.0 0.6 2.8 3 0 0 3 3 3 1 UEV domain DUF3535 PF12054.8 KFR07889.1 - 0.0079 15.5 1.5 0.014 14.7 1.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3535) UPF0242 PF06785.11 KFR07889.1 - 2.2 8.3 14.3 4.6 7.3 14.3 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Myotub-related PF06602.14 KFR07890.1 - 5.6e-146 486.0 0.2 7.6e-146 485.6 0.2 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 KFR07890.1 - 0.00083 19.2 0.1 0.0026 17.6 0.0 1.8 2 0 0 2 2 2 1 GRAM domain DSPc PF00782.20 KFR07890.1 - 0.0012 18.7 0.0 0.0034 17.2 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFR07890.1 - 0.0082 15.7 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFR07890.1 - 0.034 14.1 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Vps36_ESCRT-II PF11605.8 KFR07890.1 - 0.099 12.8 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 AA_permease_2 PF13520.6 KFR07891.1 - 1.9e-50 171.9 43.0 4.3e-50 170.8 29.3 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 KFR07891.1 - 3.3e-34 118.3 27.5 3.3e-34 118.3 27.5 2.1 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 KFR07891.1 - 2.9e-14 52.9 4.7 2.9e-14 52.9 4.7 4.1 5 0 0 5 5 5 1 C-terminus of AA_permease MAP17 PF15807.5 KFR07891.1 - 0.027 14.7 1.6 0.057 13.6 1.6 1.5 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Ig_3 PF13927.6 KFR07892.1 - 3e-17 63.0 0.8 1.4e-08 35.2 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFR07892.1 - 3e-14 52.9 0.3 3e-06 27.3 0.0 3.9 3 1 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFR07892.1 - 7.7e-13 48.3 0.0 1.1e-06 28.6 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFR07892.1 - 3.2e-10 40.2 1.7 0.0012 19.1 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFR07892.1 - 0.00016 21.8 0.3 2.6 8.3 0.3 3.6 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_6 PF18452.1 KFR07892.1 - 0.0049 16.4 0.1 0.13 11.8 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain Rotamase_3 PF13616.6 KFR07892.1 - 0.15 12.7 0.1 0.25 11.9 0.1 1.3 1 0 0 1 1 1 0 PPIC-type PPIASE domain zf-CCCH_3 PF15663.5 KFR07894.1 - 0.033 14.4 2.3 0.72 10.1 1.4 2.2 2 0 0 2 2 2 0 Zinc-finger containing family Fibrinogen_C PF00147.18 KFR07895.1 - 4.7e-78 262.0 13.7 5.8e-78 261.7 13.7 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PCM1_C PF15717.5 KFR07896.1 - 1.7e-269 895.9 49.5 1.7e-269 895.9 49.5 7.1 4 3 1 6 6 6 1 Pericentriolar material 1 C terminus DUF5347 PF17282.2 KFR07896.1 - 2.2 8.6 8.8 1.1 9.6 0.2 4.2 4 0 0 4 4 4 0 Family of unknown function (DUF5347) TFIIE_alpha PF02002.17 KFR07897.1 - 4.3e-30 103.7 1.8 9.7e-30 102.5 1.8 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 KFR07897.1 - 2.9e-26 91.6 2.0 2.9e-26 91.6 2.0 2.4 2 0 0 2 2 2 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.12 KFR07897.1 - 6.5e-07 28.8 0.9 1.4e-06 27.7 0.9 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 KFR07897.1 - 0.022 14.7 0.5 0.049 13.5 0.5 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Elf1 PF05129.13 KFR07897.1 - 0.023 14.7 0.6 0.076 13.1 0.6 1.8 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Tau95_N PF17682.1 KFR07897.1 - 0.16 12.1 2.2 0.18 12.0 0.8 1.8 2 0 0 2 2 2 0 Tau95 Triple barrel domain PyrI_C PF02748.15 KFR07897.1 - 1.4 8.8 4.5 2.8 7.9 3.2 2.2 2 1 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain CBAH PF02275.18 KFR07898.1 - 4.2e-39 135.0 0.1 4.3e-37 128.5 0.1 2.1 1 1 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family NAAA-beta PF15508.6 KFR07898.1 - 1.4e-21 76.5 0.1 3.3e-21 75.4 0.1 1.6 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase AAT PF03417.16 KFR07898.1 - 0.04 13.6 0.0 0.094 12.4 0.0 1.6 2 0 0 2 2 2 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase FRG1 PF06229.12 KFR07899.1 - 2e-80 269.0 1.2 2e-80 269.0 1.2 1.5 2 0 0 2 2 2 1 FRG1-like domain Fascin PF06268.13 KFR07899.1 - 2.7e-08 34.0 0.0 1.4e-07 31.7 0.0 2.1 3 0 0 3 3 3 1 Fascin domain DUF569 PF04601.13 KFR07899.1 - 0.00021 21.0 0.1 0.0021 17.8 0.0 2.6 1 1 0 2 2 2 1 Domain of unknown function (DUF569) AIM3 PF17096.5 KFR07899.1 - 0.085 13.8 0.1 0.085 13.8 0.1 2.1 2 1 0 2 2 2 0 Altered inheritance of mitochondria protein 3 Jak1_Phl PF17887.1 KFR07899.1 - 0.094 12.7 0.1 0.094 12.7 0.1 2.2 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain Bromodomain PF00439.25 KFR07902.1 - 6.9e-38 128.6 4.5 2.3e-21 75.6 0.1 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KFR07902.1 - 5.7e-30 103.3 0.2 1.5e-29 101.9 0.2 1.8 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation YL1 PF05764.13 KFR07902.1 - 0.00025 21.3 19.7 0.00025 21.3 19.7 2.5 2 1 0 2 2 2 1 YL1 nuclear protein V_ATPase_I PF01496.19 KFR07902.1 - 1.4 6.8 6.0 2.3 6.0 6.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CDC45 PF02724.14 KFR07902.1 - 8 4.6 16.5 14 3.9 16.5 1.4 1 0 0 1 1 1 0 CDC45-like protein Trefoil PF00088.18 KFR07905.1 - 1.3e-27 95.4 21.2 6.6e-14 51.5 8.1 2.2 2 0 0 2 2 2 2 Trefoil (P-type) domain Trypsin PF00089.26 KFR07906.1 - 5.3e-73 245.5 0.4 7.7e-73 244.9 0.4 1.2 1 0 0 1 1 1 1 Trypsin SRCR_2 PF15494.6 KFR07906.1 - 2.9e-26 91.8 2.2 5.9e-26 90.9 2.2 1.5 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFR07906.1 - 9.8e-10 38.9 1.1 2.4e-09 37.7 1.1 1.6 1 0 0 1 1 1 1 Hepsin, SRCR domain SRCR PF00530.18 KFR07906.1 - 4e-07 30.5 0.3 1.2e-06 29.0 0.3 1.8 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain DUF1986 PF09342.11 KFR07906.1 - 1e-06 29.1 0.1 2.1e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Ldl_recept_a PF00057.18 KFR07906.1 - 7.2e-06 26.1 8.0 2.3e-05 24.5 8.0 1.9 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Trypsin_2 PF13365.6 KFR07906.1 - 4.7e-05 24.3 0.0 9.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain MORN PF02493.20 KFR07907.1 - 9.1e-36 119.6 45.6 1.8e-09 36.9 3.2 7.4 7 0 0 7 7 7 7 MORN repeat MFS_1 PF07690.16 KFR07908.1 - 8.5e-36 123.6 33.9 6.6e-31 107.5 23.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KFR07908.1 - 0.00024 19.5 7.3 0.00061 18.2 2.3 2.9 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF2985 PF11204.8 KFR07908.1 - 0.009 16.1 2.2 3.1 8.0 0.0 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2985) MFS_1_like PF12832.7 KFR07908.1 - 0.027 13.3 16.0 0.028 13.3 8.1 2.6 2 1 0 2 2 2 0 MFS_1 like family Sugar_tr PF00083.24 KFR07908.1 - 2.9 6.6 28.0 0.042 12.7 5.4 2.8 2 2 0 2 2 2 0 Sugar (and other) transporter PDEase_I PF00233.19 KFR07909.1 - 1.9e-87 292.9 8.1 3.9e-87 291.9 4.1 2.1 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase DUF4897 PF16238.5 KFR07909.1 - 0.067 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) 4HB_MCP_1 PF12729.7 KFR07909.1 - 0.092 12.3 1.1 0.2 11.2 0.2 1.9 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction WD40 PF00400.32 KFR07910.1 - 1.7e-05 25.5 0.0 2 9.4 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat CNH PF00780.22 KFR07910.1 - 0.015 14.9 0.0 0.044 13.4 0.0 1.8 2 0 0 2 2 2 0 CNH domain HPS3_N PF14761.6 KFR07910.1 - 0.1 12.1 0.0 3.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 NDUFV3 PF15880.5 KFR07911.1 - 2e-14 53.3 0.6 3.2e-14 52.6 0.6 1.3 1 0 0 1 1 1 1 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial Meis_PKNOX_N PF16493.5 KFR07912.1 - 4.2e-37 126.3 0.1 8e-37 125.5 0.1 1.5 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 Homeobox_KN PF05920.11 KFR07912.1 - 7.5e-20 70.5 1.2 1.8e-19 69.3 1.2 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFR07912.1 - 4.8e-08 32.7 0.3 9.5e-08 31.8 0.3 1.5 1 0 0 1 1 1 1 Homeodomain CBS PF00571.28 KFR07913.1 - 9.4e-09 35.6 0.0 1.5e-05 25.3 0.0 2.2 2 0 0 2 2 2 2 CBS domain Poxvirus_B22R_C PF13168.6 KFR07913.1 - 0.0044 16.5 0.0 0.0051 16.3 0.0 1.1 1 0 0 1 1 1 1 Poxvirus B22R protein C-terminal PALP PF00291.25 KFR07914.1 - 1.5e-17 63.9 0.0 1.6e-17 63.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Glyco_tran_WecB PF03808.13 KFR07914.1 - 0.012 15.6 0.0 0.02 14.8 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family CbiG_N PF11760.8 KFR07914.1 - 0.03 14.3 0.0 0.036 14.1 0.0 1.1 1 0 0 1 1 1 0 Cobalamin synthesis G N-terminal Methyltransf_12 PF08242.12 KFR07914.1 - 0.056 14.2 0.0 0.25 12.1 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain DAGK_cat PF00781.24 KFR07914.1 - 0.058 13.0 0.1 0.067 12.8 0.1 1.1 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain LSDAT_prok PF18171.1 KFR07914.1 - 0.083 12.1 0.1 0.097 11.9 0.1 1.1 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote Methyltransf_25 PF13649.6 KFR07914.1 - 0.094 13.4 0.1 0.18 12.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Tubulin PF00091.25 KFR07914.1 - 0.12 12.5 0.1 0.14 12.3 0.1 1.1 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain Bmp PF02608.14 KFR07914.1 - 0.17 10.8 0.0 0.18 10.8 0.0 1.0 1 0 0 1 1 1 0 ABC transporter substrate-binding protein PnrA-like PALP PF00291.25 KFR07915.1 - 0.035 13.5 0.0 0.04 13.3 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme PALP PF00291.25 KFR07916.1 - 2.2e-67 227.5 0.0 2.9e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KFR07916.1 - 2.6e-10 40.6 0.5 5.5e-08 33.1 0.1 3.2 3 0 0 3 3 3 2 CBS domain zf-CCCH PF00642.24 KFR07917.1 - 4.5e-14 51.9 17.1 8.9e-07 28.7 3.3 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KFR07917.1 - 6.7e-07 29.0 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 KFR07917.1 - 6.4e-06 26.8 3.8 0.056 14.2 0.1 2.4 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KFR07917.1 - 1.2e-05 25.2 14.4 0.011 15.8 2.9 2.8 2 0 0 2 2 2 2 Zinc finger domain KMP11 PF03037.16 KFR07917.1 - 0.0098 16.7 0.5 0.53 11.1 0.3 2.2 2 0 0 2 2 2 1 Kinetoplastid membrane protein 11 Nup35_RRM_2 PF14605.6 KFR07917.1 - 0.042 13.8 0.1 0.078 13.0 0.1 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCCH_3 PF15663.5 KFR07917.1 - 0.14 12.4 7.0 1.4 9.1 0.8 2.4 2 0 0 2 2 2 0 Zinc-finger containing family Crystallin PF00525.18 KFR07918.1 - 2.1e-27 95.1 1.6 3.6e-27 94.3 1.6 1.4 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal HSP20 PF00011.21 KFR07918.1 - 6.2e-24 84.1 0.0 7.6e-24 83.8 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Pkinase PF00069.25 KFR07919.1 - 7.4e-69 232.0 0.1 1.9e-68 230.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR07919.1 - 8.5e-35 120.3 0.0 1.5e-34 119.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR07919.1 - 8.3e-08 31.9 0.0 1.4e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFR07919.1 - 2.1e-06 27.0 0.1 4.1e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFR07919.1 - 0.079 12.3 0.3 0.16 11.3 0.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family VHS PF00790.19 KFR07920.1 - 0.0069 16.2 0.1 0.51 10.2 0.0 2.6 2 0 0 2 2 2 1 VHS domain DUF383 PF04063.14 KFR07920.1 - 0.0074 16.0 0.2 0.015 15.0 0.2 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF383) RasGEF_N_2 PF14663.6 KFR07920.1 - 0.01 16.2 0.7 0.073 13.5 0.1 2.5 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Exonuc_VII_L PF02601.15 KFR07920.1 - 0.016 14.8 1.2 0.022 14.3 1.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mis14 PF08641.12 KFR07920.1 - 0.022 15.1 4.9 0.022 15.1 4.9 1.8 2 0 0 2 2 2 0 Kinetochore protein Mis14 like YabA PF06156.13 KFR07920.1 - 0.025 15.2 5.2 0.096 13.3 5.0 2.1 1 1 0 1 1 1 0 Initiation control protein YabA CCCAP PF15964.5 KFR07920.1 - 0.081 11.2 11.1 0.2 9.9 9.2 2.0 2 0 0 2 2 2 0 Centrosomal colon cancer autoantigen protein family Atg14 PF10186.9 KFR07920.1 - 0.29 10.2 5.7 0.67 9.0 3.5 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 KFR07920.1 - 0.35 10.9 6.7 5.1 7.2 0.2 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 KFR07920.1 - 0.49 10.5 11.0 0.049 13.7 6.6 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PEP-utilisers_N PF05524.13 KFR07920.1 - 0.66 10.2 5.2 1.2 9.3 2.8 2.2 1 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF724 PF05266.14 KFR07920.1 - 0.8 9.5 7.6 0.15 11.9 3.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4201 PF13870.6 KFR07920.1 - 1 9.1 13.5 0.21 11.3 9.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) YlqD PF11068.8 KFR07920.1 - 1.8 8.9 9.5 0.45 10.9 5.7 1.9 2 0 0 2 2 2 0 YlqD protein STAT_alpha PF01017.20 KFR07920.1 - 2.4 8.0 12.1 3.3 7.6 9.6 2.2 1 1 1 2 2 2 0 STAT protein, all-alpha domain Lectin_N PF03954.14 KFR07920.1 - 2.8 7.7 7.8 5 6.9 4.1 2.8 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain FlaC_arch PF05377.11 KFR07920.1 - 3.3 8.2 5.5 3.4 8.1 0.8 3.1 3 1 0 3 3 2 0 Flagella accessory protein C (FlaC) LPP PF04728.13 KFR07920.1 - 8.6 6.8 7.3 1.4 9.4 0.3 3.0 4 0 0 4 4 4 0 Lipoprotein leucine-zipper Nop52 PF05997.12 KFR07921.1 - 7.1e-64 215.5 2.1 7.1e-64 215.5 2.1 1.8 2 0 0 2 2 2 1 Nucleolar protein,Nop52 Phos_pyr_kin PF08543.12 KFR07922.1 - 8e-19 68.0 0.1 1.4e-18 67.2 0.1 1.3 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KFR07922.1 - 3.1e-11 43.1 0.0 1e-10 41.5 0.0 1.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HpcH_HpaI PF03328.14 KFR07922.1 - 0.0052 16.0 0.1 0.014 14.5 0.0 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family SRR1 PF07985.12 KFR07922.1 - 0.14 12.2 0.1 0.68 10.0 0.0 2.1 2 0 0 2 2 2 0 SRR1 Acyltransf_C PF16076.5 KFR07923.1 - 2.3e-28 98.1 0.2 4.4e-28 97.2 0.2 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 KFR07923.1 - 7.9e-15 54.7 0.0 1.2e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase TRAPPC10 PF12584.8 KFR07925.1 - 0.00022 20.9 0.3 0.00047 19.9 0.0 1.7 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 TRAPPC10 PF12584.8 KFR07926.1 - 6.3e-28 97.4 0.0 7.5e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.7 KFR07926.1 - 0.19 11.8 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking WD40 PF00400.32 KFR07927.1 - 3.5e-33 113.1 23.4 7e-08 33.0 0.0 11.4 13 0 0 13 13 13 4 WD domain, G-beta repeat Utp12 PF04003.12 KFR07927.1 - 4.4e-24 84.8 0.4 7e-24 84.2 0.4 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KFR07927.1 - 3e-20 72.3 0.0 0.0074 16.6 0.0 9.4 5 3 4 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFR07927.1 - 1.8e-08 34.5 0.6 0.0097 15.8 0.0 5.0 2 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFR07927.1 - 2.7e-07 29.9 0.2 0.41 9.6 0.1 4.3 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFR07927.1 - 2.5e-05 23.7 0.5 0.00023 20.6 0.2 2.6 2 1 0 2 2 2 1 WD40-like domain PD40 PF07676.12 KFR07927.1 - 4.2e-05 23.3 0.1 0.33 10.9 0.0 4.8 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Utp13 PF08625.11 KFR07927.1 - 0.013 15.4 0.3 0.044 13.7 0.3 2.0 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain Osmo_MPGsynth PF09488.10 KFR07927.1 - 0.019 13.7 0.0 0.03 13.0 0.0 1.2 1 0 0 1 1 1 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) Nup160 PF11715.8 KFR07927.1 - 0.12 11.0 4.2 0.088 11.4 0.2 2.4 2 1 0 2 2 2 0 Nucleoporin Nup120/160 DJ-1_PfpI PF01965.24 KFR07928.1 - 1.2e-06 28.4 0.3 3.8e-06 26.8 0.3 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family V-set PF07686.17 KFR07929.1 - 1.4e-13 50.9 0.7 4.1e-11 43.0 0.1 2.4 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.6 KFR07929.1 - 4.4e-11 43.2 2.8 5.9e-05 23.6 0.1 2.7 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFR07929.1 - 2.5e-09 37.2 1.6 0.00019 21.5 0.1 3.6 2 2 1 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 KFR07929.1 - 3.1e-09 36.8 0.0 1.3e-08 34.8 0.0 2.0 2 0 0 2 2 1 1 CD80-like C2-set immunoglobulin domain I-set PF07679.16 KFR07929.1 - 4.5e-08 33.1 0.0 0.0067 16.5 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFR07929.1 - 1.5e-06 28.5 1.5 0.0022 18.3 0.2 2.8 2 1 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.15 KFR07929.1 - 9.3e-05 22.7 0.7 0.0075 16.6 0.0 3.1 2 1 1 3 3 3 1 Immunoglobulin C1-set domain MLANA PF14991.6 KFR07929.1 - 0.00047 20.4 2.5 0.00075 19.8 0.9 2.1 2 1 0 2 2 2 1 Protein melan-A Lep_receptor_Ig PF06328.11 KFR07929.1 - 0.0012 18.8 2.5 0.033 14.1 0.0 3.3 3 1 1 4 4 4 1 Ig-like C2-type domain DUF4366 PF14283.6 KFR07929.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF2987 PF11205.8 KFR07929.1 - 0.097 12.6 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2987) DUF2207 PF09972.9 KFR07929.1 - 0.11 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PIP49_C PF12260.8 KFR07931.1 - 3.5e-43 147.4 0.0 6.1e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Glyco_trans_4_4 PF13579.6 KFR07931.1 - 0.1 13.0 0.2 0.16 12.4 0.2 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Pentapeptide_4 PF13599.6 KFR07932.1 - 0.019 15.1 0.3 0.13 12.4 0.3 1.9 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) Phenol_monoox PF04663.12 KFR07932.1 - 8.9 6.5 23.6 19 5.5 1.2 4.0 1 1 3 4 4 4 0 Phenol hydroxylase conserved region FUN14 PF04930.15 KFR07933.1 - 1.5e-29 102.2 2.7 1.9e-29 101.9 2.7 1.1 1 0 0 1 1 1 1 FUN14 family EutA PF06277.11 KFR07933.1 - 0.053 12.4 0.1 0.063 12.1 0.1 1.0 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA SPC12 PF06645.13 KFR07933.1 - 0.56 10.3 2.9 0.96 9.6 0.9 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF1126 PF06565.12 KFR07934.1 - 4.8e-103 338.1 2.5 9.4e-33 112.2 0.1 4.2 3 1 1 4 4 4 4 DUF1126 PH-like domain DUF5580 PF17743.1 KFR07934.1 - 0.038 12.6 0.0 0.059 11.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Cys_knot PF00007.22 KFR07935.1 - 2.4e-06 27.8 13.0 3.5e-06 27.3 13.0 1.3 1 0 0 1 1 1 1 Cystine-knot domain DAN PF03045.15 KFR07935.1 - 5.1e-06 26.5 9.3 6.1e-06 26.2 9.3 1.1 1 0 0 1 1 1 1 DAN domain SRCR PF00530.18 KFR07937.1 - 1.8e-118 387.8 31.7 4.7e-32 110.5 0.9 4.1 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFR07937.1 - 1.7e-15 57.3 18.4 0.00016 22.1 0.3 4.5 4 1 0 4 4 4 4 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFR07937.1 - 0.00017 22.1 6.0 2.7 8.6 0.0 4.6 5 0 0 5 5 5 2 Hepsin, SRCR domain Bac_chlorC PF02043.17 KFR07937.1 - 0.072 13.1 0.8 8.9 6.4 0.1 2.8 3 0 0 3 3 3 0 Bacteriochlorophyll C binding protein zf-NADH-PPase PF09297.11 KFR07937.1 - 1.1 9.0 9.7 13 5.5 0.2 4.9 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Aminotran_5 PF00266.19 KFR07945.1 - 3.3e-63 213.9 0.0 3.8e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V LRR_6 PF13516.6 KFR07946.1 - 1.9e-12 46.2 8.7 0.0045 16.9 0.1 6.8 7 0 0 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.33 KFR07946.1 - 0.052 14.1 2.1 2.3e+02 3.0 0.0 5.5 6 1 0 6 6 6 0 Leucine Rich Repeat LBP_BPI_CETP PF01273.25 KFR07946.1 - 0.074 12.7 0.1 0.81 9.3 0.1 2.2 2 0 0 2 2 2 0 LBP / BPI / CETP family, N-terminal domain G-alpha PF00503.20 KFR07947.1 - 1.2e-81 274.6 3.8 1.9e-81 274.0 3.8 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFR07947.1 - 2.3e-07 30.5 0.1 5.5e-07 29.2 0.1 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KFR07948.1 - 1.8e-107 359.5 4.3 2.1e-107 359.4 4.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFR07948.1 - 3.4e-12 46.2 2.1 5.3e-11 42.3 0.1 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family Condensation PF00668.20 KFR07948.1 - 0.025 13.3 0.2 0.038 12.7 0.2 1.2 1 0 0 1 1 1 0 Condensation domain BNIP2 PF12496.8 KFR07949.1 - 8.3e-43 146.1 3.9 1.1e-42 145.7 3.9 1.1 1 0 0 1 1 1 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CRAL_TRIO_2 PF13716.6 KFR07949.1 - 2.7e-31 108.6 0.4 4.5e-31 107.8 0.4 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KFR07949.1 - 3.8e-10 39.7 0.6 6.9e-10 38.9 0.6 1.4 1 1 0 1 1 1 1 CRAL/TRIO domain Flavokinase PF01687.17 KFR07951.1 - 6e-25 87.7 0.0 6.7e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase CD20 PF04103.15 KFR07952.1 - 0.00087 19.4 0.9 0.0016 18.5 0.9 1.4 1 0 0 1 1 1 1 CD20-like family PPTA PF01239.22 KFR07953.1 - 8e-23 79.4 10.1 1.9e-07 30.6 0.2 6.4 6 0 0 6 6 6 4 Protein prenyltransferase alpha subunit repeat MAM PF00629.23 KFR07954.1 - 1.3e-131 434.7 0.0 3.7e-43 147.2 0.0 4.0 4 0 0 4 4 4 4 MAM domain, meprin/A5/mu CBM_4_9 PF02018.17 KFR07954.1 - 0.067 13.5 1.2 0.6 10.4 0.0 2.7 3 0 0 3 3 3 0 Carbohydrate binding domain Hydrolase_4 PF12146.8 KFR07955.1 - 5.5e-13 48.7 0.0 5.6e-07 29.1 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFR07955.1 - 6.9e-08 33.4 0.0 4.2e-05 24.3 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KFR07955.1 - 6.9e-08 32.2 0.0 1e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KFR07955.1 - 2.1e-07 30.9 0.1 0.0066 16.1 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 KFR07955.1 - 0.0011 18.5 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family UPF0227 PF05728.12 KFR07955.1 - 0.0022 17.9 0.0 0.054 13.4 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) FSH1 PF03959.13 KFR07955.1 - 0.0036 17.0 0.0 0.0055 16.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 KFR07955.1 - 0.0042 16.9 0.0 0.011 15.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF818 PF05677.12 KFR07955.1 - 0.0044 16.0 0.1 0.0062 15.5 0.1 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Asp2 PF16929.5 KFR07955.1 - 0.0047 16.0 0.0 0.0066 15.5 0.0 1.1 1 0 0 1 1 1 1 Accessory Sec system GspB-transporter Abhydrolase_2 PF02230.16 KFR07955.1 - 0.025 14.4 0.0 0.26 11.1 0.0 2.1 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2039 PF10217.9 KFR07956.1 - 1.3e-24 86.4 11.6 1.4e-24 86.2 11.6 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Cript PF10235.9 KFR07956.1 - 0.0008 19.9 7.1 0.0008 19.9 7.1 1.7 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT zinc-ribbons_6 PF07191.12 KFR07956.1 - 0.0017 18.3 8.3 0.0025 17.8 8.3 1.2 1 0 0 1 1 1 1 zinc-ribbons DZR PF12773.7 KFR07956.1 - 0.18 11.8 9.5 13 5.9 9.5 2.4 1 1 0 1 1 1 0 Double zinc ribbon Amidohydro_1 PF01979.20 KFR07957.1 - 3.4e-69 233.8 0.0 3.9e-69 233.6 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFR07957.1 - 1.6e-11 44.4 0.0 3.6e-09 36.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family zf-A20 PF01754.16 KFR07958.1 - 7.1e-13 48.2 8.7 2.4e-12 46.6 8.7 2.0 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.16 KFR07958.1 - 1.7e-09 37.7 8.2 1.7e-09 37.7 8.2 1.9 2 0 0 2 2 2 1 AN1-like Zinc finger FAM53 PF15242.6 KFR07958.1 - 0.11 12.3 10.8 0.15 11.9 10.8 1.1 1 0 0 1 1 1 0 Family of FAM53 Aldedh PF00171.22 KFR07960.1 - 9.4e-167 555.2 0.0 1.1e-166 555.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Annexin PF00191.20 KFR07961.1 - 1.8e-87 287.4 12.7 1.4e-23 82.7 0.4 4.0 4 0 0 4 4 4 4 Annexin Myb_DNA-bind_7 PF15963.5 KFR07961.1 - 0.0021 17.9 0.6 2.2 8.2 0.0 3.3 2 1 1 3 3 3 2 Myb DNA-binding like GT-D PF08759.11 KFR07961.1 - 0.067 12.8 1.5 0.24 11.1 0.1 2.1 2 1 0 2 2 2 0 Glycosyltransferase GT-D fold Acetyltransf_11 PF13720.6 KFR07961.1 - 0.58 10.7 3.0 4 8.0 0.2 3.1 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Pkinase PF00069.25 KFR07964.1 - 1.9e-35 122.5 0.0 2.7e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR07964.1 - 1.4e-18 67.1 0.0 2e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR07964.1 - 2.2e-05 23.9 0.0 3.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FAM83 PF07894.12 KFR07967.1 - 8.5e-107 356.8 0.1 2.2e-106 355.4 0.1 1.8 1 0 0 1 1 1 1 FAM83 A-H PLDc_2 PF13091.6 KFR07967.1 - 7.9e-10 38.7 0.2 1.6e-09 37.7 0.2 1.5 1 0 0 1 1 1 1 PLD-like domain Regulator_TrmB PF11495.8 KFR07967.1 - 0.011 14.9 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB 7tm_1 PF00001.21 KFR07969.1 - 6.8e-58 196.0 22.0 8.5e-58 195.7 22.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Orexin_rec2 PF03827.13 KFR07969.1 - 6e-29 99.8 1.8 6e-29 99.8 1.8 2.5 3 0 0 3 3 3 1 Orexin receptor type 2 7TM_GPCR_Srsx PF10320.9 KFR07969.1 - 0.00026 20.4 20.7 0.00093 18.6 20.7 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFR07969.1 - 0.0005 19.9 10.1 0.0005 19.9 10.1 1.8 2 0 0 2 2 2 1 Olfactory receptor GDNF PF02351.16 KFR07970.1 - 1.2e-21 77.5 51.4 9.9e-11 42.5 12.9 3.7 3 1 0 3 3 3 3 GDNF/GAS1 domain HMGL-like PF00682.19 KFR07972.1 - 1.4e-66 224.8 0.0 1.5e-66 224.6 0.0 1.0 1 0 0 1 1 1 1 HMGL-like TGFb_propeptide PF00688.18 KFR07974.1 - 2.1e-93 312.6 0.0 3.4e-93 311.9 0.0 1.3 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 KFR07974.1 - 2e-37 128.3 0.6 5.6e-37 126.9 0.5 1.9 2 0 0 2 2 2 1 Transforming growth factor beta like domain YkuD_2 PF13645.6 KFR07974.1 - 0.092 12.2 1.1 0.2 11.1 0.2 1.9 2 0 0 2 2 2 0 L,D-transpeptidase catalytic domain Spectrin PF00435.21 KFR07975.1 - 3.4e-222 721.7 485.2 1.3e-16 61.0 7.0 42.2 40 3 4 44 44 43 33 Spectrin repeat CH PF00307.31 KFR07975.1 - 1.1e-37 128.5 8.2 1.7e-19 70.0 0.0 6.1 6 0 0 6 6 6 2 Calponin homology (CH) domain GAS2 PF02187.17 KFR07975.1 - 3.6e-30 103.9 0.3 1.4e-29 101.9 0.3 2.2 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Spectrin_like PF18373.1 KFR07975.1 - 1.2e-29 102.2 1.0 1.2e-29 102.2 1.0 9.7 11 0 0 11 11 8 1 Spectrin like domain SH3_10 PF17902.1 KFR07975.1 - 2.8e-20 72.2 0.2 1.1e-19 70.3 0.2 2.1 1 0 0 1 1 1 1 SH3 domain EF-hand_1 PF00036.32 KFR07975.1 - 8.8e-12 43.7 2.3 0.0001 21.6 0.8 3.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFR07975.1 - 7.9e-11 41.0 1.6 0.00037 20.2 0.4 3.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KFR07975.1 - 1.2e-09 38.5 1.0 1.2e-09 38.5 1.0 5.4 5 0 0 5 5 5 1 EF-hand domain pair EF-hand_8 PF13833.6 KFR07975.1 - 1.5e-08 34.3 0.6 3.4e-06 26.8 0.1 4.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KFR07975.1 - 1.4e-07 30.7 4.5 5e-05 22.6 1.1 3.1 2 0 0 2 2 2 2 EF hand CAMSAP_CH PF11971.8 KFR07975.1 - 2.8e-06 27.1 0.2 0.0054 16.5 0.0 3.9 3 0 0 3 3 3 2 CAMSAP CH domain Laminin_II PF06009.12 KFR07975.1 - 0.0062 16.6 0.3 0.0062 16.6 0.3 31.1 23 7 7 35 35 34 3 Laminin Domain II BEN PF10523.9 KFR07979.1 - 1e-12 48.1 0.0 2e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 BEN domain DUF1087 PF06465.13 KFR07979.1 - 0.054 13.5 0.4 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) Staufen_C PF16482.5 KFR07979.1 - 0.095 12.9 0.8 1 9.5 0.0 2.4 1 1 1 2 2 2 0 Staufen C-terminal domain bZIP_2 PF07716.15 KFR07979.1 - 0.2 11.7 0.2 0.2 11.7 0.2 1.9 2 0 0 2 2 2 0 Basic region leucine zipper PIN_11 PF18479.1 KFR07980.1 - 4.3e-64 214.0 2.5 2.1e-63 211.7 0.0 3.1 3 0 0 3 3 3 1 PIN like domain PIN7 PF18475.1 KFR07980.1 - 4.4e-05 24.0 0.2 0.00039 21.0 0.0 2.6 4 0 0 4 4 4 1 PIN domain zf-H2C2_2 PF13465.6 KFR07980.1 - 0.051 14.0 0.1 0.051 14.0 0.1 9.5 10 0 0 10 10 10 0 Zinc-finger double domain zf-C2H2_3rep PF18868.1 KFR07980.1 - 0.17 12.6 0.2 0.17 12.6 0.2 6.3 5 3 0 6 6 6 0 Zinc finger C2H2-type, 3 repeats Lipocalin PF00061.23 KFR07980.1 - 1.3 9.2 5.2 0.19 11.9 0.7 1.9 2 0 0 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family zf-C2H2_4 PF13894.6 KFR07980.1 - 1.7 9.7 94.2 1 10.4 0.6 13.7 15 0 0 15 15 15 0 C2H2-type zinc finger ORC_WH_C PF18137.1 KFR07980.1 - 2 8.5 7.6 9.4 6.3 0.2 2.8 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal DUF5100 PF17029.5 KFR07980.1 - 4.2 7.2 7.5 21 5.0 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5100) Big_3_3 PF13750.6 KFR07981.1 - 0.06 13.0 0.1 0.089 12.4 0.1 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) DUF775 PF05603.12 KFR07981.1 - 0.12 11.9 1.7 1.9 8.0 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF775) DUF3247 PF11607.8 KFR07981.1 - 0.14 12.4 2.4 1.2 9.5 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3247) Ras PF00071.22 KFR07982.1 - 5.2e-53 179.0 1.3 8.2e-53 178.3 1.3 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR07982.1 - 3.7e-33 114.3 0.4 7.2e-33 113.3 0.4 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR07982.1 - 2.7e-10 40.0 0.7 3.7e-10 39.5 0.7 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFR07982.1 - 1e-06 28.8 0.1 2.1e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFR07982.1 - 8.9e-05 22.1 0.3 0.00016 21.2 0.3 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFR07982.1 - 9.1e-05 22.4 2.4 0.014 15.3 0.2 2.3 1 1 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 KFR07982.1 - 0.00062 19.6 2.6 0.0014 18.5 0.3 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 KFR07982.1 - 0.00067 19.1 0.2 0.00086 18.7 0.2 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region YwhD PF08741.10 KFR07982.1 - 0.021 14.5 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 YwhD family FeoB_N PF02421.18 KFR07982.1 - 0.026 14.1 0.2 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B HGTP_anticodon2 PF12745.7 KFR07982.1 - 0.039 13.5 0.4 0.056 12.9 0.4 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs MMR_HSR1_Xtn PF16897.5 KFR07982.1 - 0.085 12.9 0.3 0.17 11.9 0.3 1.6 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DNA_primase_lrg PF04104.14 KFR07983.1 - 2.8e-95 318.7 0.0 5.2e-95 317.9 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Sam68-YY PF16568.5 KFR07985.1 - 1.4e-19 70.6 32.7 2.7e-19 69.7 32.7 1.5 1 0 0 1 1 1 1 Tyrosine-rich domain of Sam68 KH_1 PF00013.29 KFR07985.1 - 3e-09 36.5 0.0 5.5e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 KH domain Qua1 PF16274.5 KFR07985.1 - 6e-07 29.2 4.7 6e-07 29.2 4.7 2.1 2 0 0 2 2 2 1 Qua1 domain Gln-synt_C PF00120.24 KFR07988.1 - 1.6e-73 247.7 0.0 2.6e-73 247.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KFR07988.1 - 4.2e-07 29.6 0.1 1.4e-05 24.7 0.1 2.7 3 0 0 3 3 3 1 Glutamine synthetase, beta-Grasp domain Gln-synt_N_2 PF16952.5 KFR07988.1 - 8.1e-06 25.6 0.0 8e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 Glutamine synthetase N-terminal domain Y_phosphatase PF00102.27 KFR07989.1 - 2.3e-08 33.9 0.0 1.1e-07 31.7 0.0 1.8 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFR07989.1 - 1e-07 31.8 0.0 1.5e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain TFIIS_M PF07500.14 KFR07990.1 - 2e-31 108.8 3.6 2e-31 108.8 3.6 3.2 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 KFR07990.1 - 2.2e-28 99.1 0.0 8.3e-28 97.2 0.0 2.1 1 0 0 1 1 1 1 SPOC domain PHD PF00628.29 KFR07990.1 - 4.3e-09 36.1 9.8 1.4e-08 34.5 9.8 2.0 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.6 KFR07990.1 - 0.024 14.8 5.1 0.086 13.0 5.1 2.0 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFR07990.1 - 0.14 12.4 6.5 0.27 11.5 3.5 2.9 2 0 0 2 2 2 0 PHD-like zinc-binding domain Laminin_G_2 PF02210.24 KFR07991.1 - 6.9e-37 126.8 0.4 2e-17 63.9 0.1 2.1 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 KFR07991.1 - 2.5e-33 115.1 0.1 2.7e-17 63.2 0.0 2.1 2 0 0 2 2 2 2 Laminin G domain EGF PF00008.27 KFR07991.1 - 1e-08 35.3 19.7 0.00031 21.0 2.6 2.9 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 KFR07991.1 - 0.0036 17.9 5.2 0.0036 17.9 5.2 5.0 5 0 0 5 5 5 2 Human growth factor-like EGF Laminin_G_3 PF13385.6 KFR07991.1 - 0.0038 17.4 0.1 2.4 8.3 0.1 2.4 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily FXa_inhibition PF14670.6 KFR07991.1 - 0.011 16.0 21.5 0.058 13.7 5.2 2.7 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site EGF_2 PF07974.13 KFR07991.1 - 0.015 15.6 12.4 0.015 15.6 12.4 2.9 2 1 0 2 2 2 0 EGF-like domain NPCBM_assoc PF10633.9 KFR07991.1 - 0.16 12.2 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase EGF_3 PF12947.7 KFR07991.1 - 0.26 11.5 17.0 0.43 10.8 3.0 2.9 2 0 0 2 2 2 0 EGF domain EGF_CA PF07645.15 KFR07991.1 - 9.8 6.5 23.9 2.2e+02 2.2 18.3 2.8 1 1 1 2 2 2 0 Calcium-binding EGF domain Laminin_G_2 PF02210.24 KFR07992.1 - 1.4e-23 83.8 1.6 2.7e-19 70.0 0.2 2.1 2 0 0 2 2 2 2 Laminin G domain EGF PF00008.27 KFR07992.1 - 2.8e-21 75.5 53.3 1.3e-05 25.3 10.9 4.7 4 0 0 4 4 4 4 EGF-like domain Laminin_G_1 PF00054.23 KFR07992.1 - 1.2e-20 74.0 0.2 6.1e-16 58.8 0.1 2.1 2 0 0 2 2 2 2 Laminin G domain hEGF PF12661.7 KFR07992.1 - 3.7e-09 36.9 47.3 0.0013 19.3 7.4 5.8 5 0 0 5 5 5 4 Human growth factor-like EGF EGF_2 PF07974.13 KFR07992.1 - 1.9e-05 24.9 57.0 0.02 15.2 11.2 4.9 4 1 0 4 4 4 3 EGF-like domain EGF PF00008.27 KFR07993.1 - 3e-93 305.5 199.2 1.5e-09 38.0 8.6 15.3 15 0 0 15 15 15 14 EGF-like domain hEGF PF12661.7 KFR07993.1 - 3.7e-64 211.3 185.4 1.2e-06 28.9 2.7 17.4 18 0 0 18 18 18 14 Human growth factor-like EGF EGF_CA PF07645.15 KFR07993.1 - 3.5e-41 139.2 203.4 9.1e-08 32.2 4.7 14.6 13 2 1 14 14 14 14 Calcium-binding EGF domain EGF_2 PF07974.13 KFR07993.1 - 1.7e-19 69.9 212.9 0.00085 19.6 5.2 14.6 14 0 0 14 14 14 11 EGF-like domain EGF_3 PF12947.7 KFR07993.1 - 3.3e-08 33.6 176.4 0.0099 16.1 5.4 15.6 11 2 3 14 14 14 9 EGF domain Laminin_EGF PF00053.24 KFR07993.1 - 1.5e-05 25.0 172.3 0.34 11.1 4.1 14.4 4 2 10 14 14 14 9 Laminin EGF domain cEGF PF12662.7 KFR07993.1 - 0.004 17.1 1.6 0.004 17.1 1.6 18.1 17 3 1 18 18 18 8 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 KFR07993.1 - 0.016 15.3 5.0 0.016 15.3 5.0 14.4 14 0 0 14 14 14 0 MSP1 EGF domain 1 nos_propeller_2 PF18793.1 KFR07993.1 - 0.04 14.3 0.0 35 4.8 0.0 4.0 5 0 0 5 5 5 0 Nitrous oxide reductase propeller repeat 2 EGF PF00008.27 KFR07995.1 - 1.3e-25 89.4 56.2 1.9e-07 31.3 7.8 5.4 5 0 0 5 5 5 5 EGF-like domain hEGF PF12661.7 KFR07995.1 - 9.3e-13 48.3 60.2 0.00038 21.0 4.2 6.8 7 1 0 7 7 7 5 Human growth factor-like EGF EGF_2 PF07974.13 KFR07995.1 - 1.8e-10 41.0 61.7 9.1e-05 22.7 4.1 5.6 5 1 0 5 5 5 4 EGF-like domain EGF_CA PF07645.15 KFR07995.1 - 2.1e-06 27.8 56.9 0.053 13.7 0.0 5.5 3 2 2 5 5 5 4 Calcium-binding EGF domain EGF_3 PF12947.7 KFR07995.1 - 1.4e-05 25.2 44.9 0.027 14.7 5.6 5.5 4 2 1 5 5 5 4 EGF domain Laminin_EGF PF00053.24 KFR07995.1 - 0.0005 20.2 47.5 0.46 10.7 8.6 4.6 1 1 3 4 4 4 3 Laminin EGF domain Plasmod_Pvs28 PF06247.11 KFR07995.1 - 0.022 15.1 38.7 0.26 11.6 6.0 4.5 4 0 0 4 4 4 0 Pvs28 EGF domain FXa_inhibition PF14670.6 KFR07995.1 - 0.068 13.5 51.1 0.56 10.5 6.7 5.4 4 2 1 5 5 5 0 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFR07995.1 - 0.079 12.9 1.0 0.079 12.9 1.0 5.5 5 1 1 6 6 6 0 Complement Clr-like EGF-like DUF2165 PF09933.9 KFR07996.1 - 0.11 12.5 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) WD40 PF00400.32 KFR07999.1 - 1 10.3 5.5 8.3 7.5 0.0 4.1 4 1 0 4 4 4 0 WD domain, G-beta repeat AMOP PF03782.17 KFR08006.1 - 9.9e-52 174.9 7.3 2.2e-51 173.7 7.3 1.6 1 0 0 1 1 1 1 AMOP domain VWD PF00094.25 KFR08006.1 - 1.8e-17 64.1 0.3 5.8e-17 62.4 0.3 1.9 2 0 0 2 2 2 1 von Willebrand factor type D domain Sushi PF00084.20 KFR08006.1 - 1.3e-08 35.3 1.0 5.5e-08 33.3 0.9 2.3 2 0 0 2 2 2 1 Sushi repeat (SCR repeat) Somatomedin_B PF01033.17 KFR08006.1 - 1.2e-05 25.6 12.3 1.2e-05 25.6 12.3 2.4 2 0 0 2 2 2 1 Somatomedin B domain ZNRF_3_ecto PF18212.1 KFR08007.1 - 5.1e-47 158.2 0.0 8.8e-47 157.4 0.0 1.4 1 0 0 1 1 1 1 ZNRF-3 Ectodomain zf-RING_2 PF13639.6 KFR08007.1 - 1.3e-11 44.6 9.5 1.3e-11 44.6 9.5 3.0 3 0 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 KFR08007.1 - 1.8e-11 43.6 3.5 1.3e-10 40.8 2.5 2.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFR08007.1 - 7.5e-08 32.1 9.1 7.5e-08 32.1 9.1 3.0 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFR08007.1 - 3.4e-06 26.8 8.7 3.4e-06 26.8 8.7 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFR08007.1 - 6.5e-05 22.7 6.9 0.00014 21.6 5.7 2.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFR08007.1 - 9.2e-05 22.3 7.7 0.00044 20.2 7.7 2.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFR08007.1 - 0.00037 20.5 7.5 0.00077 19.4 5.7 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFR08007.1 - 0.00074 19.3 6.7 0.00074 19.3 6.7 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFR08007.1 - 0.00087 19.5 12.7 0.00087 19.5 12.7 2.8 3 1 0 3 3 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFR08007.1 - 0.021 14.9 3.3 0.091 12.8 3.3 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PA PF02225.22 KFR08007.1 - 0.045 13.8 0.1 0.12 12.4 0.0 1.7 2 0 0 2 2 1 0 PA domain Baculo_RING PF05883.11 KFR08007.1 - 0.15 12.1 1.0 0.83 9.6 0.2 2.4 2 1 0 2 2 2 0 Baculovirus U-box/Ring-like domain Cadherin_C_2 PF16492.5 KFR08007.1 - 0.18 12.6 2.1 0.19 12.5 0.2 2.1 2 0 0 2 2 1 0 Cadherin cytoplasmic C-terminal WD40 PF00400.32 KFR08025.1 - 5.8e-28 96.6 15.1 2.8e-05 24.8 0.0 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR08025.1 - 5e-13 49.2 0.0 8e-05 22.9 0.0 4.8 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 KFR08025.1 - 4.7e-09 35.8 1.4 2.4e-08 33.5 0.0 2.4 2 0 0 2 2 2 1 LisH-like dimerisation domain CAMSAP_CKK PF08683.11 KFR08026.1 - 3.1e-54 182.2 0.1 6e-54 181.3 0.1 1.5 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated CAMSAP_CH PF11971.8 KFR08026.1 - 2.1e-36 123.6 2.0 5.7e-36 122.2 2.0 1.8 1 0 0 1 1 1 1 CAMSAP CH domain CAMSAP_CC1 PF17095.5 KFR08026.1 - 1.1e-24 86.0 4.9 1.1e-24 86.0 4.9 3.1 2 0 0 2 2 2 1 Spectrin-binding region of Ca2+-Calmodulin CH PF00307.31 KFR08026.1 - 0.037 14.2 0.0 0.19 12.0 0.0 2.2 1 0 0 1 1 1 0 Calponin homology (CH) domain DEAD PF00270.29 KFR08028.1 - 1.6e-43 148.5 2.2 2e-43 148.2 0.7 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFR08028.1 - 3.3e-21 75.7 0.0 1.9e-19 70.0 0.0 3.0 1 1 2 3 3 3 1 Helicase conserved C-terminal domain zf-HIT PF04438.16 KFR08028.1 - 1.5e-07 31.2 1.3 2.6e-07 30.4 1.3 1.4 1 0 0 1 1 1 1 HIT zinc finger ResIII PF04851.15 KFR08028.1 - 2.2e-05 24.5 0.0 5.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 KFR08028.1 - 0.017 14.5 0.2 0.53 9.5 0.0 2.4 2 0 0 2 2 2 0 SecA DEAD-like domain CMS1 PF14617.6 KFR08028.1 - 0.033 13.5 0.2 0.1 11.9 0.2 1.9 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA PF00004.29 KFR08028.1 - 0.034 14.6 0.3 0.11 13.0 0.2 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 KFR08028.1 - 0.039 13.5 0.6 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Toprim_C_rpt PF13368.6 KFR08028.1 - 0.14 12.2 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat AMP-binding PF00501.28 KFR08028.1 - 0.18 10.4 0.0 1.3 7.5 0.0 2.1 2 0 0 2 2 2 0 AMP-binding enzyme Kinesin PF00225.23 KFR08029.1 - 2.6e-107 358.6 0.1 2.6e-107 358.6 0.1 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFR08029.1 - 1.7e-25 89.7 0.1 1.7e-25 89.7 0.1 2.8 2 0 0 2 2 2 1 Microtubule binding Kinesin_assoc PF16183.5 KFR08029.1 - 5.9e-14 52.6 21.0 9.6e-12 45.4 0.6 4.3 3 1 1 4 4 4 2 Kinesin-associated FHA PF00498.26 KFR08029.1 - 1.3e-08 35.0 0.2 3.6e-08 33.6 0.2 1.8 1 0 0 1 1 1 1 FHA domain KIF1B PF12423.8 KFR08029.1 - 0.02 15.3 1.7 0.15 12.5 0.1 3.0 2 0 0 2 2 2 0 Kinesin protein 1B Gluconate_2-dh3 PF13618.6 KFR08029.1 - 4.5 7.5 9.8 0.47 10.7 3.9 2.4 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 zf-C4 PF00105.18 KFR08030.1 - 2.5e-32 111.2 12.0 4.2e-32 110.4 12.0 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFR08030.1 - 6.1e-31 107.6 5.7 9.5e-31 107.0 5.7 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DUF2431 PF10354.9 KFR08030.1 - 0.12 12.7 0.0 0.31 11.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2431) Y_phosphatase PF00102.27 KFR08031.1 - 3.9e-159 527.4 1.7 7.6e-83 277.7 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFR08031.1 - 1.2e-06 28.7 0.0 0.066 13.2 0.0 2.3 2 0 0 2 2 2 2 Tyrosine phosphatase family fn3 PF00041.21 KFR08031.1 - 4e-05 23.9 6.0 0.0024 18.2 0.1 5.2 6 0 0 6 6 6 1 Fibronectin type III domain PTPlike_phytase PF14566.6 KFR08031.1 - 0.0016 18.6 0.0 0.52 10.4 0.0 3.3 3 0 0 3 3 3 1 Inositol hexakisphosphate DSPc PF00782.20 KFR08031.1 - 0.0071 16.2 0.0 0.044 13.6 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 KFR08031.1 - 0.038 13.6 0.0 13 5.3 0.0 2.7 2 0 0 2 2 2 0 Tyrosine phosphatase family SCIMP PF15050.6 KFR08031.1 - 0.044 14.2 0.1 0.18 12.3 0.1 2.1 1 0 0 1 1 1 0 SCIMP protein Anti-adapt_IraP PF10796.9 KFR08031.1 - 0.12 13.0 0.0 0.34 11.5 0.0 1.7 1 0 0 1 1 1 0 Sigma-S stabilisation anti-adaptor protein ATE_N PF04376.13 KFR08031.1 - 0.33 11.4 2.0 0.64 10.5 0.0 2.4 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, N terminus V-ATPase_G PF03179.15 KFR08032.1 - 1.4e-34 118.7 14.0 1.6e-34 118.6 14.0 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit FdhE PF04216.12 KFR08032.1 - 0.0031 17.4 3.3 0.0036 17.2 3.3 1.0 1 0 0 1 1 1 1 Protein involved in formate dehydrogenase formation DUF3552 PF12072.8 KFR08032.1 - 0.023 14.1 17.0 0.042 13.3 17.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4407 PF14362.6 KFR08032.1 - 0.11 11.8 6.0 0.12 11.7 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF760 PF05542.11 KFR08032.1 - 0.14 12.5 1.1 0.33 11.3 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF760) Prominin PF05478.11 KFR08032.1 - 0.18 9.7 6.1 0.2 9.6 6.1 1.0 1 0 0 1 1 1 0 Prominin Gti1_Pac2 PF09729.9 KFR08032.1 - 0.21 11.7 8.5 0.24 11.5 8.5 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family V-ATPase_G_2 PF16999.5 KFR08032.1 - 0.27 11.7 15.0 5.5 7.5 11.2 2.1 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit OmpH PF03938.14 KFR08032.1 - 0.32 11.3 16.1 0.43 10.9 16.1 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Muted PF14942.6 KFR08032.1 - 0.42 11.0 14.0 0.97 9.8 14.0 1.7 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein ATP-synt_B PF00430.18 KFR08032.1 - 0.92 9.6 13.8 1.6 8.8 13.8 1.4 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) DUF883 PF05957.13 KFR08032.1 - 1 10.0 8.9 2.5 8.8 6.3 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) P4Ha_N PF08336.11 KFR08032.1 - 2.1 8.4 10.6 16 5.5 10.8 1.9 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region RabGAP-TBC PF00566.18 KFR08032.1 - 3.2 7.3 6.7 15 5.1 6.7 1.8 1 1 0 1 1 1 0 Rab-GTPase-TBC domain Exonuc_VII_L PF02601.15 KFR08032.1 - 5.7 6.4 9.8 6.3 6.3 9.8 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit EMC3_TMCO1 PF01956.16 KFR08032.1 - 7.8 6.2 11.3 13 5.5 11.3 1.4 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like CENP-H PF05837.12 KFR08032.1 - 8.3 6.9 14.2 12 6.3 14.2 1.4 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Pkinase PF00069.25 KFR08033.1 - 1.5e-65 221.2 0.0 1.9e-65 220.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR08033.1 - 4.6e-48 163.7 0.0 5.7e-48 163.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR08033.1 - 5.3e-06 26.0 0.0 8.4e-06 25.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFR08033.1 - 1.7e-05 23.9 0.0 3.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KFR08033.1 - 0.00026 19.9 0.0 0.00033 19.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PIP49_C PF12260.8 KFR08033.1 - 0.0039 16.9 0.3 0.22 11.1 0.1 2.2 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 Kdo PF06293.14 KFR08033.1 - 0.0051 16.2 0.1 0.0082 15.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF309 PF03745.14 KFR08033.1 - 0.12 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF309) Gln_deamidase_2 PF18626.1 KFR08033.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutaminase APH PF01636.23 KFR08033.1 - 0.16 11.9 0.0 0.58 10.0 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family DENN PF02141.21 KFR08034.1 - 1.3e-48 165.4 3.5 2.2e-48 164.7 3.5 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 KFR08034.1 - 2.8e-10 40.0 1.0 7.2e-10 38.7 1.0 1.8 1 0 0 1 1 1 1 dDENN domain EGF PF00008.27 KFR08035.1 - 6.4e-93 304.5 282.6 4.3e-08 33.3 7.4 20.1 19 1 0 19 19 19 17 EGF-like domain Laminin_G_2 PF02210.24 KFR08035.1 - 2.3e-51 173.6 0.7 3e-21 76.3 0.0 3.3 3 0 0 3 3 3 3 Laminin G domain hEGF PF12661.7 KFR08035.1 - 2.3e-50 167.6 231.5 0.00012 22.5 2.3 20.9 20 0 0 20 20 20 17 Human growth factor-like EGF Laminin_G_1 PF00054.23 KFR08035.1 - 3.9e-38 130.6 0.3 1.9e-14 54.0 0.0 3.7 4 0 0 4 4 4 3 Laminin G domain EGF_CA PF07645.15 KFR08035.1 - 1.4e-17 63.6 273.8 9.5e-05 22.5 8.0 20.0 17 3 3 20 20 20 14 Calcium-binding EGF domain EGF_2 PF07974.13 KFR08035.1 - 1.5e-13 50.9 296.0 0.1 13.0 6.6 19.2 18 1 0 18 18 18 14 EGF-like domain Laminin_G_3 PF13385.6 KFR08035.1 - 5.9e-07 29.7 0.0 0.0088 16.2 0.0 3.3 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily cEGF PF12662.7 KFR08035.1 - 0.00043 20.2 14.7 0.0022 17.9 2.7 17.8 18 1 0 18 18 18 9 Complement Clr-like EGF-like EGF_3 PF12947.7 KFR08035.1 - 0.012 15.8 2.3 0.012 15.8 2.3 19.8 19 0 0 19 19 19 0 EGF domain zf-H2C2_2 PF13465.6 KFR08036.1 - 6.7e-48 159.1 128.0 1.9e-06 28.0 2.3 15.6 16 0 0 16 16 16 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFR08036.1 - 9.2e-47 155.0 137.5 0.00013 22.2 1.3 14.7 14 0 0 14 14 14 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR08036.1 - 2.6e-35 118.0 131.4 0.0059 17.3 2.6 14.7 14 0 0 14 14 14 14 C2H2-type zinc finger BTB PF00651.31 KFR08036.1 - 4.5e-21 75.1 0.5 1.3e-20 73.7 0.5 1.8 1 0 0 1 1 1 1 BTB/POZ domain zf-met PF12874.7 KFR08036.1 - 5.2e-09 36.2 87.1 0.00045 20.5 1.4 13.9 14 0 0 14 14 14 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFR08036.1 - 2.5e-07 30.5 118.9 0.019 14.9 2.9 13.7 14 0 0 14 14 14 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFR08036.1 - 1e-05 25.6 88.6 0.027 14.8 2.5 13.7 14 0 0 14 14 14 5 Zinc-finger double-stranded RNA-binding SDA1 PF05285.12 KFR08036.1 - 0.025 14.0 15.3 0.052 13.0 15.3 1.5 1 0 0 1 1 1 0 SDA1 zf-C2H2_2 PF12756.7 KFR08036.1 - 0.037 14.4 0.2 0.037 14.4 0.2 13.1 3 1 7 11 11 11 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 KFR08036.1 - 0.039 13.8 17.6 4.9 7.0 0.1 6.5 4 2 3 7 7 7 0 GAGA factor zf-C2HC_2 PF13913.6 KFR08036.1 - 0.09 12.7 0.2 0.073 13.0 1.9 12.3 14 0 0 14 14 13 0 zinc-finger of a C2HC-type Thioredoxin_2 PF13098.6 KFR08036.1 - 0.16 12.4 1.7 1.1 9.8 1.7 2.5 1 0 0 1 1 1 0 Thioredoxin-like domain BolA PF01722.18 KFR08036.1 - 0.29 11.4 9.9 15 6.0 0.1 5.2 3 2 1 5 5 5 0 BolA-like protein Sushi PF00084.20 KFR08037.1 - 6.2e-57 190.0 60.3 4.9e-10 39.9 1.2 9.3 9 0 0 9 9 9 8 Sushi repeat (SCR repeat) Sushi_2 PF09014.10 KFR08037.1 - 0.00037 20.3 18.1 0.0046 16.8 0.9 5.6 5 2 1 6 6 6 2 Beta-2-glycoprotein-1 fifth domain DUF1962 PF09227.10 KFR08037.1 - 0.09 13.2 10.7 3.7 8.0 0.1 4.8 5 0 0 5 5 5 0 Domain of unknown function (DUF1962) RMI1_N PF08585.12 KFR08044.1 - 5.3e-30 104.8 3.2 6.4e-23 81.6 0.0 3.6 2 2 1 3 3 3 2 RecQ mediated genome instability protein SMN PF06003.12 KFR08044.1 - 3.3e-10 39.7 0.0 3.3e-10 39.7 0.0 2.5 2 1 0 2 2 2 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 KFR08044.1 - 6.6e-10 39.1 0.0 1.3e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Tudor domain UBA PF00627.31 KFR08044.1 - 1.2e-07 31.5 0.1 2.3e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain COE1_DBD PF16422.5 KFR08051.1 - 3.5e-125 416.0 5.0 1.4e-124 414.1 5.0 1.8 1 1 0 1 1 1 1 Transcription factor COE1 DNA-binding domain COE1_HLH PF16423.5 KFR08051.1 - 3.3e-25 87.5 3.6 3.4e-18 65.1 0.5 3.1 3 0 0 3 3 3 2 Transcription factor COE1 helix-loop-helix domain AP-5_subunit_s1 PF15001.6 KFR08052.1 - 5.6e-41 140.7 0.0 6.1e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 AP-5 complex subunit sigma-1 DUF4517 PF15006.6 KFR08053.1 - 6.4e-52 175.8 0.0 7.6e-52 175.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4517) TrpBP PF02081.15 KFR08053.1 - 0.0078 16.0 0.4 4.7 7.1 0.0 2.3 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein HSP70 PF00012.20 KFR08054.1 - 3.4e-05 22.2 0.1 0.085 11.0 0.0 2.2 2 0 0 2 2 2 2 Hsp70 protein SPATA19 PF15212.6 KFR08054.1 - 0.041 14.1 0.1 0.16 12.2 0.0 2.0 3 0 0 3 3 3 0 Spermatogenesis-associated protein 19, mitochondrial SMI1_KNR4 PF09346.10 KFR08054.1 - 0.17 12.3 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) Ig_2 PF13895.6 KFR08055.1 - 1.9e-53 178.7 6.9 5.1e-13 49.2 0.1 6.1 6 0 0 6 6 6 6 Immunoglobulin domain Ig_3 PF13927.6 KFR08055.1 - 4.5e-45 152.1 10.5 1.1e-12 48.4 0.1 6.3 6 0 0 6 6 6 5 Immunoglobulin domain I-set PF07679.16 KFR08055.1 - 9e-40 134.6 2.3 1.3e-07 31.6 0.1 7.4 6 3 0 6 6 6 5 Immunoglobulin I-set domain ig PF00047.25 KFR08055.1 - 2.4e-28 98.1 7.5 1.4e-05 25.2 0.0 6.8 6 3 0 6 6 6 5 Immunoglobulin domain V-set PF07686.17 KFR08055.1 - 1.1e-25 89.9 5.9 0.012 15.8 0.1 8.7 6 3 3 9 9 9 8 Immunoglobulin V-set domain Ig_4 PF16680.5 KFR08055.1 - 1.6e-14 53.9 0.0 0.028 14.7 0.0 4.8 5 0 0 5 5 5 3 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFR08055.1 - 1.1e-13 51.4 0.1 0.028 14.8 0.0 5.5 5 0 0 5 5 5 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFR08055.1 - 3.7e-13 49.3 0.0 0.053 13.6 0.0 5.3 5 0 0 5 5 5 3 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 KFR08055.1 - 1.9e-10 40.7 2.8 7.5e-06 25.9 0.7 3.9 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFR08055.1 - 3.1e-10 39.4 0.0 0.16 11.5 0.0 5.2 5 0 0 5 5 5 3 Immunoglobulin domain C1-set PF07654.15 KFR08055.1 - 9.9e-09 35.5 1.8 0.053 13.9 0.0 4.8 4 1 0 4 4 4 3 Immunoglobulin C1-set domain C2-set PF05790.15 KFR08055.1 - 5.4e-05 23.3 0.1 0.91 9.8 0.0 5.3 6 0 0 6 6 6 1 Immunoglobulin C2-set domain Receptor_2B4 PF11465.8 KFR08055.1 - 0.0016 18.7 0.0 4.7 7.5 0.0 4.3 4 0 0 4 4 4 1 Natural killer cell receptor 2B4 Homeodomain PF00046.29 KFR08056.1 - 2.2e-13 49.8 2.4 2.6e-13 49.6 2.4 1.1 1 0 0 1 1 1 1 Homeodomain HTH_AsnC-type PF13404.6 KFR08056.1 - 0.045 13.6 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain ATP-synt_ab PF00006.25 KFR08057.1 - 8.2e-67 225.0 0.0 1.1e-66 224.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KFR08057.1 - 2.9e-10 40.5 0.2 5.3e-10 39.7 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF188 PF02639.14 KFR08057.1 - 0.17 11.6 0.0 0.44 10.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized BCR, YaiI/YqxD family COG1671 RRM_1 PF00076.22 KFR08059.1 - 0.0025 17.6 0.0 0.0061 16.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-met PF12874.7 KFR08059.1 - 0.45 11.0 3.5 1 9.9 3.5 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Alpha_kinase PF02816.18 KFR08063.1 - 3.4e-33 115.3 0.0 4.4e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Tsg PF04668.12 KFR08063.1 - 0.0048 17.6 0.3 0.0068 17.1 0.3 1.4 1 0 0 1 1 1 1 Twisted gastrulation (Tsg) protein conserved region Peptidase_C14 PF00656.22 KFR08064.1 - 2.2e-21 77.0 0.0 3.7e-20 72.9 0.0 1.9 1 1 0 1 1 1 1 Caspase domain Trehalose_PPase PF02358.16 KFR08064.1 - 0.079 12.1 0.0 0.35 10.0 0.0 2.0 2 0 0 2 2 2 0 Trehalose-phosphatase CIF PF16374.5 KFR08064.1 - 0.086 12.9 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Cycle inhibiting factor (CIF) zf-C2H2 PF00096.26 KFR08065.1 - 2.2e-22 78.2 120.3 0.0025 18.2 0.5 15.5 15 0 0 15 15 15 11 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KFR08065.1 - 2.1e-17 62.6 70.5 2.2e-16 59.3 3.8 10.1 12 0 0 12 12 12 5 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KFR08065.1 - 3.4e-16 58.6 111.8 0.0033 18.1 0.3 15.5 15 0 0 15 15 15 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFR08065.1 - 9.1e-07 29.0 0.4 0.00028 21.1 0.1 10.5 14 0 0 14 14 14 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFR08065.1 - 5e-06 26.4 0.1 5e-06 26.4 0.1 11.0 12 0 0 12 12 12 3 C2H2-type zinc finger zf-met PF12874.7 KFR08065.1 - 0.001 19.4 3.2 0.019 15.4 0.3 12.2 14 0 0 14 14 14 4 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KFR08065.1 - 0.018 15.5 91.4 0.036 14.5 3.0 14.4 16 1 0 16 16 16 0 Zinc-finger double domain DUF3079 PF11278.8 KFR08065.1 - 0.042 13.7 1.8 0.15 11.9 1.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3079) zf_ZIC PF18366.1 KFR08065.1 - 0.74 10.0 8.0 3.6 7.8 1.6 3.6 2 1 1 3 3 3 0 Zic proteins zinc finger domain Peptidase_S24 PF00717.23 KFR08066.1 - 5.1e-11 42.4 0.2 8e-11 41.7 0.2 1.3 1 0 0 1 1 1 1 Peptidase S24-like Synaphin PF05835.12 KFR08067.1 - 1.2e-47 161.7 10.6 1.7e-47 161.3 10.6 1.2 1 0 0 1 1 1 1 Synaphin protein Lectin_leg-like PF03388.13 KFR08068.1 - 5e-79 264.9 0.1 6.9e-79 264.4 0.1 1.2 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 KFR08068.1 - 6.6e-10 39.3 0.3 1.3e-09 38.4 0.3 1.4 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 KFR08068.1 - 0.00076 19.1 0.0 0.0019 17.8 0.0 1.7 1 1 0 1 1 1 1 Legume lectin domain Abi_C PF14355.6 KFR08068.1 - 0.13 12.4 0.1 0.37 10.9 0.0 1.8 2 0 0 2 2 2 0 Abortive infection C-terminus DUF3175 PF11373.8 KFR08068.1 - 0.16 12.2 0.0 28 5.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3175) DUF3086 PF11285.8 KFR08068.1 - 0.17 10.9 3.9 0.29 10.2 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) Mis14 PF08641.12 KFR08068.1 - 0.19 12.0 3.8 0.77 10.1 0.4 2.4 2 0 0 2 2 2 0 Kinetochore protein Mis14 like V-SNARE PF05008.15 KFR08068.1 - 0.21 12.0 4.7 0.37 11.2 1.2 2.9 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DASH_Dad1 PF08649.10 KFR08068.1 - 0.58 10.4 4.7 0.99 9.6 0.8 2.9 3 0 0 3 3 3 0 DASH complex subunit Dad1 DUF148 PF02520.17 KFR08068.1 - 0.79 9.8 7.4 4.3 7.5 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF148 AAA_32 PF13654.6 KFR08068.1 - 1.2 7.8 10.2 2.3 6.9 6.6 2.0 1 1 1 2 2 2 0 AAA domain KxDL PF10241.9 KFR08068.1 - 2.3 8.6 10.3 0.31 11.4 0.4 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein WXG100 PF06013.12 KFR08068.1 - 2.3 8.5 4.6 3.3 8.0 0.3 2.9 3 1 1 4 4 4 0 Proteins of 100 residues with WXG DUF4404 PF14357.6 KFR08068.1 - 3.5 8.3 8.3 16 6.2 1.5 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) SHE3 PF17078.5 KFR08068.1 - 5.9 6.5 8.7 11 5.6 0.2 2.3 1 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 Xan_ur_permease PF00860.20 KFR08077.1 - 1.1e-49 169.2 17.3 4.3e-28 98.1 5.9 2.2 2 0 0 2 2 2 2 Permease family MFS_MOT1 PF16983.5 KFR08077.1 - 0.034 14.6 11.5 3 8.3 0.6 3.5 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily PAX PF00292.18 KFR08100.1 - 2.9e-66 221.1 0.2 4.5e-66 220.5 0.2 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 KFR08100.1 - 7.3e-07 28.8 0.2 2e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 KFR08100.1 - 1.3e-05 25.7 0.3 0.00028 21.5 0.0 2.3 1 1 1 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KFR08100.1 - 0.0086 16.1 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 KFR08100.1 - 0.042 14.0 0.0 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Mito_carr PF00153.27 KFR08101.1 - 3.5e-46 155.1 1.1 9.7e-15 54.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Forkhead PF00250.18 KFR08103.1 - 3.4e-39 133.0 0.3 3.9e-39 132.8 0.3 1.0 1 0 0 1 1 1 1 Forkhead domain DpnI_C PF17726.1 KFR08103.1 - 0.039 14.1 0.3 0.057 13.6 0.3 1.2 1 0 0 1 1 1 0 Dam-replacing HTH domain PAP_fibrillin PF04755.12 KFR08103.1 - 0.19 11.6 0.0 0.24 11.3 0.0 1.0 1 0 0 1 1 1 0 PAP_fibrillin TPR_1 PF00515.28 KFR08104.1 - 2.4e-66 217.0 60.2 4e-06 26.4 0.2 17.9 19 1 0 19 19 18 14 Tetratricopeptide repeat TPR_2 PF07719.17 KFR08104.1 - 3.4e-57 186.0 46.8 1.5e-06 27.8 0.0 18.6 18 2 0 18 18 17 13 Tetratricopeptide repeat TPR_11 PF13414.6 KFR08104.1 - 3e-49 164.4 29.4 1.9e-06 27.5 1.0 14.9 9 5 6 15 15 15 9 TPR repeat TPR_9 PF13371.6 KFR08104.1 - 1.3e-39 134.2 0.1 6.7e-06 26.2 0.0 9.2 2 2 7 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 KFR08104.1 - 5.4e-39 129.1 44.5 6.8e-06 25.9 0.0 16.7 18 1 1 19 19 17 10 Tetratricopeptide repeat TPR_17 PF13431.6 KFR08104.1 - 9.8e-32 107.0 25.1 0.00029 21.0 0.9 12.6 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_16 PF13432.6 KFR08104.1 - 2e-27 95.5 0.3 0.00065 20.3 0.0 10.5 6 4 5 12 12 12 6 Tetratricopeptide repeat TPR_12 PF13424.6 KFR08104.1 - 2.1e-25 88.8 27.3 6e-07 29.7 0.0 12.4 7 3 5 12 12 12 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFR08104.1 - 6.9e-22 76.3 2.4 0.17 12.8 0.0 12.4 7 4 6 13 13 12 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFR08104.1 - 4.2e-19 68.8 14.8 5.6e-07 30.0 0.0 9.2 6 3 4 10 10 9 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFR08104.1 - 5.2e-15 54.3 10.0 0.13 12.4 0.0 10.4 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFR08104.1 - 3.6e-10 39.8 28.5 1.6 9.5 0.0 12.6 15 0 0 15 15 12 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFR08104.1 - 1.7e-09 37.7 34.8 0.001 19.3 2.0 7.0 7 0 0 7 7 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KFR08104.1 - 9.8e-08 31.5 2.3 1.1 8.5 0.0 6.3 2 1 1 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFR08104.1 - 4e-05 23.3 17.9 6.8 6.7 0.0 9.0 10 0 0 10 10 10 1 Tetratricopeptide repeat NARP1 PF12569.8 KFR08104.1 - 6.7e-05 22.0 6.4 2.4 7.0 0.1 5.7 3 2 3 6 6 6 2 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 KFR08104.1 - 0.0014 18.9 0.6 13 6.2 0.0 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFR08104.1 - 0.0094 16.0 12.3 1.3 9.2 0.0 5.9 5 1 1 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat ANAPC5 PF12862.7 KFR08104.1 - 0.016 15.3 10.3 5 7.3 0.1 5.9 5 2 0 5 5 5 0 Anaphase-promoting complex subunit 5 COPI_C PF06957.11 KFR08104.1 - 0.03 13.1 0.2 0.38 9.5 0.1 2.5 3 0 0 3 3 3 0 Coatomer (COPI) alpha subunit C-terminus CPG4 PF15481.6 KFR08104.1 - 0.033 14.8 3.1 0.18 12.5 1.4 3.1 1 1 1 2 2 2 0 Chondroitin proteoglycan 4 BTAD PF03704.17 KFR08104.1 - 0.08 13.4 2.1 35 4.8 0.0 5.0 5 2 0 5 5 5 0 Bacterial transcriptional activator domain RPN13_C PF16550.5 KFR08104.1 - 0.092 12.9 0.0 3.3 7.9 0.0 3.0 3 0 0 3 3 2 0 UCH-binding domain SHNi-TPR PF10516.9 KFR08104.1 - 0.25 10.8 16.1 0.28 10.7 0.1 7.5 10 0 0 10 10 10 0 SHNi-TPR 7tm_1 PF00001.21 KFR08105.1 - 1.2e-63 214.9 27.0 1.6e-63 214.5 27.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR08105.1 - 4.5e-14 52.4 23.8 5.6e-14 52.1 23.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFR08105.1 - 6e-10 39.2 22.7 1.8e-09 37.6 22.7 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFR08105.1 - 6.8e-09 35.5 14.7 6.8e-09 35.5 14.7 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFR08105.1 - 0.00026 20.8 22.8 0.00054 19.8 22.8 1.5 1 1 0 1 1 1 1 Olfactory receptor Piezo_RRas_bdg PF12166.8 KFR08105.1 - 0.0044 16.4 1.1 0.14 11.4 0.2 2.3 2 0 0 2 2 2 1 Piezo non-specific cation channel, R-Ras-binding domain T2SSM PF04612.12 KFR08105.1 - 0.076 13.1 0.2 0.076 13.1 0.2 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M COX7C PF02935.16 KFR08105.1 - 0.35 11.1 8.1 0.52 10.6 0.3 2.8 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIIc DUF3995 PF13160.6 KFR08105.1 - 6.4 7.2 11.5 8.5 6.8 3.3 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF3995) Sec23_trunk PF04811.15 KFR08106.1 - 1.5e-79 267.0 0.0 2.1e-79 266.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KFR08106.1 - 4.6e-33 113.8 0.0 1e-32 112.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KFR08106.1 - 1.1e-27 95.9 0.1 2.7e-27 94.6 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 KFR08106.1 - 2.7e-15 56.0 0.0 8.6e-15 54.4 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 KFR08106.1 - 2.8e-15 56.1 6.7 5.1e-15 55.2 6.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger APP_E2 PF12925.7 KFR08106.1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein SIP1 PF04938.12 KFR08107.1 - 2.7e-68 230.0 0.4 3e-68 229.8 0.4 1.0 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) TRAPP PF04051.16 KFR08108.1 - 3.9e-44 149.9 0.1 4.4e-44 149.7 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Pinin_SDK_memA PF04696.13 KFR08109.1 - 5.8e-34 117.0 21.6 5.8e-34 117.0 21.6 6.1 5 2 1 7 7 7 1 pinin/SDK/memA/ protein conserved region Pinin_SDK_N PF04697.13 KFR08109.1 - 3.7e-29 102.1 3.7 3.7e-29 102.1 3.7 5.1 4 2 2 6 6 6 1 pinin/SDK conserved region zf-H2C2_2 PF13465.6 KFR08111.1 - 1.5e-23 82.1 31.5 1.8e-06 28.1 0.3 6.3 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFR08111.1 - 3.5e-23 80.7 26.7 2.8e-05 24.3 0.1 5.5 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR08111.1 - 2.5e-14 52.8 28.1 0.0012 19.5 4.0 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFR08111.1 - 3.5e-05 23.5 13.4 0.4 10.5 0.1 3.7 3 0 0 3 3 3 3 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFR08111.1 - 7.7e-05 22.5 8.5 0.21 11.5 0.0 4.8 5 0 0 5 5 5 2 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.5 KFR08111.1 - 8.7e-05 22.8 7.8 0.012 15.9 1.5 3.6 2 1 3 5 5 5 2 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KFR08111.1 - 0.00013 22.2 7.9 2.1 8.5 0.1 4.3 1 1 3 4 4 4 2 Aberrant zinc-finger zf-met PF12874.7 KFR08111.1 - 0.0017 18.7 7.5 0.94 10.0 0.1 4.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFR08111.1 - 0.014 15.6 8.5 2.4 8.5 0.0 4.5 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding CpXC PF14353.6 KFR08111.1 - 0.12 12.4 0.9 9 6.4 0.0 2.9 2 1 1 3 3 3 0 CpXC protein CHORD PF04968.12 KFR08111.1 - 0.25 12.1 13.6 4.4 8.1 0.1 4.9 2 1 3 5 5 5 0 CHORD zf-DNA_Pol PF08996.10 KFR08111.1 - 0.41 10.4 3.3 3 7.5 0.6 2.5 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf-C2H2_6 PF13912.6 KFR08111.1 - 0.6 10.2 31.1 6.2 6.9 0.2 6.1 5 1 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFR08111.1 - 1.4 9.3 9.8 0.79 10.1 1.0 3.6 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) UPF0564 PF10595.9 KFR08112.1 - 2.6e-76 257.1 45.1 3.4e-76 256.7 45.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0564 FAD_binding_3 PF01494.19 KFR08113.1 - 8.2e-19 68.0 0.7 1.5e-10 40.9 0.2 3.0 3 0 0 3 3 3 2 FAD binding domain SE PF08491.10 KFR08113.1 - 0.00015 20.9 0.0 0.00031 19.9 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.14 KFR08113.1 - 0.00047 19.1 0.5 0.42 9.4 0.0 3.1 3 0 0 3 3 3 2 Tryptophan halogenase GDA1_CD39 PF01150.17 KFR08114.1 - 2e-78 263.9 0.0 7.8e-78 262.0 0.0 1.7 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Aldedh PF00171.22 KFR08115.1 - 6.1e-121 404.1 0.0 6.9e-121 404.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KFR08115.1 - 0.079 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) LIN52 PF10044.9 KFR08117.1 - 1.6e-17 64.0 0.0 1.7e-17 63.9 0.0 1.0 1 0 0 1 1 1 1 Retinal tissue protein Homeodomain PF00046.29 KFR08118.1 - 2.6e-23 81.6 1.5 3.4e-23 81.2 1.5 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFR08118.1 - 0.002 18.0 0.1 0.0033 17.3 0.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain AMP-binding PF00501.28 KFR08119.1 - 6e-20 71.2 0.0 6.4e-20 71.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DUF1967 PF09269.11 KFR08119.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) AMP-binding_C PF13193.6 KFR08120.1 - 7e-17 62.2 0.2 1.1e-16 61.5 0.2 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KFR08120.1 - 5.6e-10 38.4 0.1 1e-09 37.5 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme ABC_membrane_2 PF06472.15 KFR08121.1 - 9.2e-79 264.6 1.7 1.3e-78 264.2 1.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KFR08121.1 - 1.7e-17 64.2 0.0 3e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_30 PF13604.6 KFR08121.1 - 0.00043 20.0 0.3 0.003 17.3 0.3 2.0 1 1 0 1 1 1 1 AAA domain SbmA_BacA PF05992.12 KFR08121.1 - 0.0042 16.6 2.2 0.0068 15.9 2.2 1.4 1 1 0 1 1 1 1 SbmA/BacA-like family AAA_16 PF13191.6 KFR08121.1 - 0.0057 17.1 0.1 0.014 15.8 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KFR08121.1 - 0.0069 16.2 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KFR08121.1 - 0.012 15.1 0.1 0.022 14.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DEAD PF00270.29 KFR08121.1 - 0.034 13.9 0.2 0.41 10.4 0.2 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.6 KFR08121.1 - 0.062 13.6 0.5 0.29 11.4 0.2 2.2 2 0 0 2 2 2 0 AAA domain IRK PF01007.20 KFR08121.1 - 0.1 12.4 0.9 0.19 11.6 0.9 1.4 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain RsgA_GTPase PF03193.16 KFR08121.1 - 0.11 12.4 0.3 0.21 11.5 0.3 1.3 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 KFR08121.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 KFR08121.1 - 0.16 12.5 0.2 0.31 11.5 0.2 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KFR08121.1 - 0.16 12.0 0.1 0.93 9.6 0.2 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase Roc PF08477.13 KFR08121.1 - 0.18 12.0 0.5 0.71 10.1 0.2 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PhoH PF02562.16 KFR08121.1 - 0.21 11.0 0.0 0.76 9.2 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein HTH_Tnp_1 PF01527.20 KFR08122.1 - 9.4e-09 35.5 0.7 0.019 15.2 0.1 4.6 4 0 0 4 4 4 2 Transposase HTH_Tnp_1_2 PF13022.6 KFR08122.1 - 1.9e-06 28.1 1.7 2 8.6 0.1 4.3 4 0 0 4 4 4 2 Helix-turn-helix of insertion element transposase HTH_23 PF13384.6 KFR08122.1 - 6.4e-05 22.6 7.7 0.66 9.8 0.1 4.6 5 0 0 5 5 5 2 Homeodomain-like domain DUF1492 PF07374.11 KFR08122.1 - 0.00012 22.2 2.1 2.7 8.2 0.0 4.2 4 0 0 4 4 4 1 Protein of unknown function (DUF1492) Cnl2_NKP2 PF09447.10 KFR08122.1 - 0.038 14.1 1.7 5.9 7.1 0.0 3.6 3 0 0 3 3 3 0 Cnl2/NKP2 family protein Cbl_N2 PF02761.14 KFR08122.1 - 0.051 14.3 0.4 6.4 7.6 0.0 3.1 3 0 0 3 3 3 0 CBL proto-oncogene N-terminus, EF hand-like domain OTU PF02338.19 KFR08122.1 - 0.057 13.9 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 OTU-like cysteine protease Creb_binding PF09030.10 KFR08122.1 - 0.08 13.6 0.1 0.26 12.0 0.1 1.9 1 0 0 1 1 1 0 Creb binding HTH_28 PF13518.6 KFR08122.1 - 0.19 11.9 8.6 13 6.0 0.0 4.9 5 0 0 5 5 5 0 Helix-turn-helix domain HTH_29 PF13551.6 KFR08122.1 - 0.24 11.5 2.5 5.3 7.2 0.0 3.5 4 0 0 4 4 4 0 Winged helix-turn helix CD225 PF04505.12 KFR08123.1 - 9.2e-18 64.2 0.2 1.5e-17 63.5 0.2 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein Fe-S_biosyn PF01521.20 KFR08124.1 - 1.1e-08 35.2 0.0 2.5e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis E1_DerP2_DerF2 PF02221.15 KFR08125.1 - 8.3e-28 97.5 0.1 9.8e-28 97.2 0.1 1.0 1 0 0 1 1 1 1 ML domain HECT PF00632.25 KFR08126.1 - 2.1e-71 240.9 0.2 3.4e-71 240.3 0.2 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Filamin PF00630.19 KFR08126.1 - 1.6e-11 45.0 0.5 3.2e-07 31.1 0.0 3.7 3 1 0 3 3 3 2 Filamin/ABP280 repeat PLU-1 PF08429.11 KFR08126.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 PLU-1-like protein Fcf1 PF04900.12 KFR08127.1 - 9.3e-40 135.0 2.3 1.2e-39 134.6 2.3 1.2 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KFR08127.1 - 3.1e-11 43.6 0.0 3.8e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 PIN like domain Imm-NTF2 PF15655.6 KFR08127.1 - 0.057 13.7 0.0 0.094 13.0 0.0 1.3 1 0 0 1 1 1 0 NTF2 fold immunity protein 2-oxoacid_dh PF00198.23 KFR08128.1 - 8.3e-81 270.9 0.2 1e-80 270.6 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFR08128.1 - 2.3e-22 78.6 0.5 4.1e-22 77.8 0.5 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KFR08128.1 - 0.0049 16.7 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like HlyD_D23 PF16576.5 KFR08128.1 - 0.087 12.0 0.0 0.61 9.3 0.0 2.0 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion GCV_H PF01597.19 KFR08128.1 - 0.17 11.8 0.8 0.42 10.5 0.8 1.7 1 1 0 1 1 1 0 Glycine cleavage H-protein PDGF PF00341.17 KFR08129.1 - 1.5e-26 92.5 5.3 1.7e-26 92.3 5.3 1.0 1 0 0 1 1 1 1 PDGF/VEGF domain IF-2B PF01008.17 KFR08130.1 - 6.7e-82 274.9 0.1 7.5e-82 274.7 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family MSC PF09402.10 KFR08130.1 - 0.14 11.6 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Acylphosphatase PF00708.18 KFR08131.1 - 5.2e-15 55.6 0.0 6.2e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase zf-C2HC_2 PF13913.6 KFR08132.1 - 9.1e-15 54.1 10.8 2.9e-07 30.2 1.6 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-CHCC PF10276.9 KFR08132.1 - 8.3e-05 22.6 2.6 0.033 14.2 0.3 2.4 2 0 0 2 2 2 2 Zinc-finger domain zf-H2C2_2 PF13465.6 KFR08132.1 - 0.035 14.5 3.1 2.7 8.6 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2HC5 PF06221.13 KFR08132.1 - 0.039 13.9 1.2 1 9.4 0.5 2.4 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-C2H2_4 PF13894.6 KFR08132.1 - 0.074 13.9 10.0 3 8.9 0.4 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger Nairovirus_M PF07948.11 KFR08132.1 - 0.079 11.2 0.3 0.14 10.3 0.3 1.3 1 0 0 1 1 1 0 Nairovirus M polyprotein-like zinc_ribbon_9 PF14369.6 KFR08132.1 - 0.086 13.1 2.7 0.59 10.5 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon zf-CpG_bind_C PF12269.8 KFR08132.1 - 0.14 11.9 4.7 3.1 7.5 1.9 2.2 1 1 0 2 2 2 0 CpG binding protein zinc finger C terminal domain Prok-RING_4 PF14447.6 KFR08132.1 - 0.34 10.8 3.1 0.82 9.6 0.1 2.5 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-AN1 PF01428.16 KFR08132.1 - 0.45 10.7 4.2 14 5.9 0.3 2.7 3 0 0 3 3 3 0 AN1-like Zinc finger zf-Di19 PF05605.12 KFR08132.1 - 0.54 10.6 4.6 2.2 8.6 0.4 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FYVE PF01363.21 KFR08132.1 - 0.62 10.2 8.3 0.65 10.2 3.1 2.3 2 1 0 2 2 2 0 FYVE zinc finger zf-C4_ClpX PF06689.13 KFR08132.1 - 0.98 9.4 5.3 7.2 6.6 2.0 2.6 2 0 0 2 2 2 0 ClpX C4-type zinc finger zf-C2H2 PF00096.26 KFR08132.1 - 2.6 8.7 8.3 8.2 7.1 0.0 3.1 2 1 1 3 3 3 0 Zinc finger, C2H2 type zf_C2H2_6 PF18450.1 KFR08132.1 - 6.3 6.6 6.5 21 4.9 0.1 2.5 2 0 0 2 2 2 0 Zinc Finger domain Pkinase PF00069.25 KFR08133.1 - 3.8e-47 160.9 0.0 5.7e-47 160.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RCC1 PF00415.18 KFR08133.1 - 6.7e-47 157.9 23.7 1e-12 48.5 0.1 8.0 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFR08133.1 - 2e-33 113.5 16.8 2e-08 33.8 0.3 7.3 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.17 KFR08133.1 - 7e-30 104.2 0.0 1.5e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFR08133.1 - 1.8e-05 23.7 0.0 2.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFR08133.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFR08133.1 - 0.17 11.2 0.1 0.3 10.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EMP24_GP25L PF01105.24 KFR08134.1 - 8.7e-37 126.8 0.1 1.1e-36 126.5 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD bZIP_1 PF00170.21 KFR08135.1 - 8.8e-11 41.7 21.5 1.4e-10 41.1 21.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFR08135.1 - 5e-08 32.9 22.4 8.7e-08 32.1 22.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFR08135.1 - 3.3e-07 30.7 15.2 5.2e-07 30.1 15.2 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Macoilin PF09726.9 KFR08135.1 - 0.079 11.5 9.8 0.096 11.2 9.8 1.0 1 0 0 1 1 1 0 Macoilin family bZIP_1 PF00170.21 KFR08136.1 - 4.2e-11 42.8 9.0 5.8e-11 42.3 9.0 1.1 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFR08136.1 - 8.8e-10 38.5 12.4 1.1e-09 38.3 12.4 1.1 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFR08136.1 - 4.1e-07 30.4 9.5 5.6e-07 30.0 9.5 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor Phlebovirus_NSM PF07246.11 KFR08136.1 - 0.00056 19.4 0.2 0.00065 19.2 0.2 1.2 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M TMCO5 PF14992.6 KFR08136.1 - 0.014 15.0 2.7 0.017 14.7 2.7 1.1 1 0 0 1 1 1 0 TMCO5 family APG6_N PF17675.1 KFR08136.1 - 0.025 15.1 4.4 0.03 14.8 4.4 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region HALZ PF02183.18 KFR08136.1 - 0.036 14.3 2.6 0.036 14.3 2.6 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper SR-25 PF10500.9 KFR08136.1 - 0.11 12.1 8.8 0.13 11.9 8.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AAA_11 PF13086.6 KFR08136.1 - 0.16 11.7 3.9 0.19 11.5 3.9 1.1 1 0 0 1 1 1 0 AAA domain DivIC PF04977.15 KFR08136.1 - 3 7.7 7.3 9.8 6.0 7.3 1.8 1 1 0 1 1 1 0 Septum formation initiator MFS_1 PF07690.16 KFR08137.1 - 1.2e-31 110.0 45.2 5.6e-30 104.5 29.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KFR08137.1 - 0.002 16.5 7.5 0.002 16.5 7.5 2.4 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family SYS1 PF09801.9 KFR08137.1 - 6.8 6.8 13.7 0.1 12.7 3.2 2.8 3 1 0 3 3 3 0 Integral membrane protein S linking to the trans Golgi network Erg28 PF03694.13 KFR08138.1 - 3.9e-09 36.9 4.7 5.1e-09 36.5 4.7 1.2 1 0 0 1 1 1 1 Erg28 like protein DUF1427 PF07235.11 KFR08138.1 - 0.054 13.4 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1427) TGF_beta PF00019.20 KFR08140.1 - 2.4e-24 86.3 1.0 4.1e-24 85.6 1.0 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFR08140.1 - 1.3e-20 74.2 0.0 1.7e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide IFT43 PF15305.6 KFR08141.1 - 3.3e-44 150.3 3.1 4e-44 150.1 3.1 1.1 1 0 0 1 1 1 1 Intraflagellar transport protein 43 Hormone_recep PF00104.30 KFR08143.1 - 6.4e-31 107.6 0.6 1e-30 106.9 0.6 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFR08143.1 - 6.9e-31 106.5 12.3 1.3e-30 105.7 12.3 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Vasohibin PF14822.6 KFR08144.1 - 4.2e-99 330.7 0.0 4.9e-99 330.5 0.0 1.0 1 0 0 1 1 1 1 Vasohibin zf-C3HC4 PF00097.25 KFR08146.1 - 0.00018 21.3 7.4 0.00036 20.4 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFR08146.1 - 0.019 14.8 8.6 0.053 13.4 8.6 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFR08146.1 - 0.03 14.2 8.4 0.052 13.4 8.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFR08146.1 - 0.49 10.8 10.1 0.82 10.1 10.1 1.4 1 0 0 1 1 1 0 Ring finger domain CiPC PF15800.5 KFR08147.1 - 8.3e-110 367.7 9.5 9.9e-110 367.4 9.5 1.1 1 0 0 1 1 1 1 Clock interacting protein circadian DHHC PF01529.20 KFR08148.1 - 3.8e-21 75.6 8.5 3.8e-21 75.6 8.5 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase InaF-motif PF15018.6 KFR08148.1 - 0.11 12.4 3.6 0.26 11.2 3.6 1.7 1 0 0 1 1 1 0 TRP-interacting helix RSN1_7TM PF02714.15 KFR08149.1 - 1.2e-58 198.6 27.9 1.2e-58 198.6 27.9 2.0 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KFR08149.1 - 9.6e-50 169.2 0.4 1.4e-49 168.7 0.4 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KFR08149.1 - 8.8e-24 84.0 3.0 8.8e-24 84.0 3.0 5.3 5 2 1 6 6 6 2 Late exocytosis, associated with Golgi transport Globin PF00042.22 KFR08150.1 - 4.5e-10 40.1 0.0 1.1e-09 38.9 0.0 1.6 2 0 0 2 2 2 1 Globin PMT PF02366.18 KFR08152.1 - 2.4e-79 266.4 13.8 2.4e-79 266.4 13.8 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KFR08152.1 - 2.7e-54 183.8 6.7 2.7e-54 183.8 6.7 1.8 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KFR08152.1 - 5.3e-23 81.8 0.2 7.8e-23 81.3 0.2 1.1 1 0 0 1 1 1 1 MIR domain GST_N_3 PF13417.6 KFR08153.1 - 2.5e-16 59.8 0.0 4e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFR08153.1 - 9.3e-16 57.9 0.0 2e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFR08153.1 - 6.3e-14 52.0 0.0 1.1e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFR08153.1 - 2.4e-08 34.1 0.0 4e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFR08153.1 - 0.00045 20.4 0.0 0.00092 19.4 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFR08153.1 - 0.0049 16.9 0.0 0.0083 16.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KFR08153.1 - 0.057 14.0 0.0 0.086 13.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KFR08153.1 - 0.11 12.7 0.0 0.39 11.0 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin Kelch_4 PF13418.6 KFR08154.1 - 1.6e-25 88.8 0.1 3.2e-06 27.0 0.0 4.4 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KFR08154.1 - 1.5e-20 73.0 0.7 4.1e-05 23.8 0.0 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFR08154.1 - 2.2e-16 59.4 0.0 0.0022 17.9 0.0 4.4 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.25 KFR08154.1 - 8e-13 47.8 0.0 0.0079 15.8 0.1 3.5 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 KFR08154.1 - 1.1e-12 47.7 0.3 0.013 15.8 0.1 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 KFR08154.1 - 8.2e-10 38.3 1.3 0.00031 20.6 0.0 4.4 3 2 1 4 4 4 2 Kelch motif GOLD_2 PF13897.6 KFR08155.1 - 1.5e-70 236.0 1.4 1.5e-70 236.0 1.4 1.8 2 0 0 2 2 2 1 Golgi-dynamics membrane-trafficking Vps16_C PF04840.12 KFR08157.1 - 5.9e-10 38.7 1.2 0.00069 18.8 0.2 2.2 2 0 0 2 2 2 2 Vps16, C-terminal region Aha1_N PF09229.11 KFR08158.1 - 1.6e-42 145.0 0.8 2.5e-42 144.4 0.8 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KFR08158.1 - 6.8e-24 84.5 0.6 6.8e-24 84.5 0.6 1.8 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein AMOP PF03782.17 KFR08159.1 - 2.1e-26 92.7 1.2 2.1e-26 92.7 1.2 1.9 2 0 0 2 2 2 1 AMOP domain TSP_1 PF00090.19 KFR08159.1 - 2.6e-07 30.8 11.8 2.6e-07 30.8 11.8 2.3 2 0 0 2 2 2 1 Thrombospondin type 1 domain CDC45 PF02724.14 KFR08159.1 - 0.089 11.1 9.8 0.12 10.6 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 KFR08159.1 - 0.1 12.2 10.2 0.16 11.5 10.2 1.3 1 0 0 1 1 1 0 PPP4R2 Bac_transf PF02397.16 KFR08159.1 - 0.11 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial sugar transferase PTPRCAP PF15713.5 KFR08159.1 - 0.12 12.7 22.7 0.33 11.2 22.7 1.7 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CobT PF06213.12 KFR08159.1 - 0.47 9.8 14.6 0.69 9.2 14.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Merozoite_SPAM PF07133.11 KFR08159.1 - 0.5 10.3 27.8 0.79 9.7 27.8 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) BUD22 PF09073.10 KFR08159.1 - 0.74 9.1 12.1 1.1 8.6 12.1 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KFR08159.1 - 1.2 7.3 17.9 1.5 7.0 17.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KFR08159.1 - 1.3 8.4 16.9 1.8 7.9 16.9 1.2 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.13 KFR08159.1 - 2.5 7.9 13.9 3.8 7.4 13.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 KFR08159.1 - 6.3 4.8 23.2 9.6 4.2 23.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi Aminotran_1_2 PF00155.21 KFR08160.1 - 3.8e-60 204.0 0.0 4.4e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFR08160.1 - 0.0023 16.9 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFR08160.1 - 0.021 14.1 0.0 0.033 13.5 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase 2OG-FeII_Oxy_2 PF13532.6 KFR08161.1 - 6.5e-38 130.9 0.0 1.3e-37 129.9 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SKIP_SNW PF02731.15 KFR08162.1 - 2.5e-74 248.3 7.6 2.5e-74 248.3 7.6 2.2 2 0 0 2 2 2 1 SKIP/SNW domain SIR4_SID PF16991.5 KFR08162.1 - 0.36 10.8 3.1 0.87 9.6 3.1 1.6 1 0 0 1 1 1 0 Sir4 SID domain ABC1 PF03109.16 KFR08163.1 - 2.1e-38 131.1 0.0 3.7e-38 130.4 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 KFR08163.1 - 2.6e-06 27.0 0.0 0.0011 18.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 KFR08163.1 - 0.0015 18.5 0.1 0.16 11.9 0.2 2.7 2 0 0 2 2 2 2 Phosphotransferase enzyme family CENP-T_C PF15511.6 KFR08207.1 - 1.8e-08 34.5 0.1 2.2e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KFR08207.1 - 2.6e-05 24.3 0.2 3.5e-05 23.9 0.2 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KFR08207.1 - 4.8e-05 23.7 0.1 6.4e-05 23.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 KFR08207.1 - 0.00017 21.9 0.3 0.0002 21.7 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFR08207.1 - 0.00029 21.1 0.1 0.00044 20.5 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFR08207.1 - 0.006 16.7 0.0 0.0067 16.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KFR08207.1 - 0.024 14.6 0.1 0.037 14.0 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KFR08207.1 - 0.21 11.4 0.1 0.26 11.0 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone PF00125.24 KFR08209.1 - 6.8e-54 181.7 2.3 7.6e-54 181.6 2.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KFR08209.1 - 8.4e-05 22.6 0.3 0.00015 21.8 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KFR08209.1 - 0.00019 22.0 1.2 0.00023 21.8 1.2 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 KFR08209.1 - 0.00042 20.6 0.0 0.00064 20.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KFR08209.1 - 0.011 16.0 0.1 0.022 15.0 0.1 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFR08209.1 - 0.11 12.6 0.1 0.21 11.7 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit PXT1 PF15214.6 KFR08210.1 - 0.13 12.6 0.4 0.31 11.4 0.1 1.8 2 0 0 2 2 2 0 Peroxisomal testis-specific protein 1 CENP-T_C PF15511.6 KFR08211.1 - 1.8e-08 34.5 0.1 2.2e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KFR08211.1 - 2.5e-05 24.4 0.2 3.5e-05 23.9 0.2 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KFR08211.1 - 4.6e-05 23.7 0.1 6.1e-05 23.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 KFR08211.1 - 0.00017 21.9 0.3 0.00019 21.8 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFR08211.1 - 0.00028 21.1 0.1 0.00046 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFR08211.1 - 0.0059 16.7 0.0 0.0067 16.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KFR08211.1 - 0.024 14.6 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KFR08211.1 - 0.21 11.4 0.1 0.25 11.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) LRR_8 PF13855.6 KFR08213.1 - 7.7e-16 57.6 13.4 7.3e-11 41.7 5.9 2.6 1 1 1 2 2 2 2 Leucine rich repeat GPS PF01825.21 KFR08213.1 - 1.3e-07 32.0 0.0 1.3e-07 32.0 0.0 3.4 4 0 0 4 4 4 1 GPCR proteolysis site, GPS, motif I-set PF07679.16 KFR08213.1 - 2.1e-06 27.7 0.0 5.6e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_4 PF12799.7 KFR08213.1 - 8.5e-05 22.8 14.7 0.0011 19.4 1.7 2.9 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) ig PF00047.25 KFR08213.1 - 0.00065 19.8 0.2 0.0022 18.1 0.1 2.0 2 0 0 2 2 2 1 Immunoglobulin domain HRM PF02793.22 KFR08213.1 - 0.0011 19.2 1.0 0.003 17.8 1.0 1.8 1 0 0 1 1 1 1 Hormone receptor domain LRR_5 PF13306.6 KFR08213.1 - 0.0027 17.7 0.0 0.0083 16.1 0.0 1.9 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFR08213.1 - 0.0083 16.5 4.1 1.4 9.7 0.3 3.8 2 0 0 2 2 2 1 Leucine Rich Repeat LRR_9 PF14580.6 KFR08213.1 - 0.079 12.5 0.3 0.15 11.6 0.3 1.4 1 0 0 1 1 1 0 Leucine-rich repeat TPKR_C2 PF16920.5 KFR08213.1 - 0.76 10.0 4.0 1.4 9.1 1.3 2.8 2 0 0 2 2 2 0 Tyrosine-protein kinase receptor C2 Ig-like domain RRM_1 PF00076.22 KFR08214.1 - 1.1e-06 28.3 0.0 2.2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Yae1_N PF09811.9 KFR08215.1 - 1.8e-16 59.5 56.8 1.8e+04 -21.6 56.8 5.4 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Sod_Cu PF00080.20 KFR08216.1 - 2.4e-33 115.3 0.2 2.9e-33 115.0 0.2 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF2353 PF09789.9 KFR08217.1 - 1.8e-91 306.8 24.2 2.8e-91 306.2 24.2 1.3 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Baculo_VP39 PF04501.12 KFR08217.1 - 0.012 15.2 0.6 0.02 14.4 0.6 1.3 1 0 0 1 1 1 0 Baculovirus major capsid protein VP39 Csm1_N PF18504.1 KFR08217.1 - 0.016 15.5 26.3 0.023 15.0 1.9 5.3 5 0 0 5 5 5 0 Csm1 N-terminal domain CorA PF01544.18 KFR08217.1 - 0.043 13.1 17.1 0.011 15.1 7.9 2.4 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein TSC22 PF01166.18 KFR08217.1 - 0.049 13.9 0.1 0.049 13.9 0.1 5.3 5 0 0 5 5 5 0 TSC-22/dip/bun family THP2 PF09432.10 KFR08217.1 - 0.078 13.0 6.9 0.21 11.6 4.9 2.4 2 0 0 2 2 2 0 Tho complex subunit THP2 TPR_MLP1_2 PF07926.12 KFR08217.1 - 0.11 12.6 28.1 0.19 11.8 0.9 4.5 4 1 0 4 4 4 0 TPR/MLP1/MLP2-like protein Peptidase_M27 PF01742.17 KFR08217.1 - 0.11 11.6 0.2 0.16 11.0 0.2 1.2 1 0 0 1 1 1 0 Clostridial neurotoxin zinc protease LPP PF04728.13 KFR08217.1 - 0.12 12.7 7.5 12 6.3 0.1 4.3 4 0 0 4 4 4 0 Lipoprotein leucine-zipper HrpB7 PF09486.10 KFR08217.1 - 0.17 12.3 12.4 0.032 14.6 6.6 2.6 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) FapA PF03961.13 KFR08217.1 - 0.17 10.4 17.5 0.021 13.5 1.2 3.1 2 1 0 3 3 3 0 Flagellar Assembly Protein A CALCOCO1 PF07888.11 KFR08217.1 - 0.23 10.3 24.3 0.031 13.2 19.8 1.8 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4482 PF14818.6 KFR08217.1 - 0.32 11.9 21.4 0.64 10.9 1.9 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4482) DivIVA PF05103.13 KFR08217.1 - 0.44 10.6 18.4 0.22 11.6 5.9 3.0 3 0 0 3 3 3 0 DivIVA protein COG2 PF06148.11 KFR08217.1 - 0.56 10.3 10.5 1.6 8.9 0.3 3.2 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 GAS PF13851.6 KFR08217.1 - 1 8.6 32.5 0.052 12.9 5.6 4.0 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding LMBR1 PF04791.16 KFR08217.1 - 1.1 8.0 6.9 1.9 7.3 6.9 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein OEP PF02321.18 KFR08217.1 - 1.2 8.9 10.9 3 7.6 10.9 1.7 1 0 0 1 1 1 0 Outer membrane efflux protein HAP1_N PF04849.13 KFR08217.1 - 1.4 8.0 28.4 0.053 12.7 11.6 3.7 2 1 1 4 4 4 0 HAP1 N-terminal conserved region KLRAQ PF10205.9 KFR08217.1 - 1.7 8.9 20.1 8 6.8 8.9 4.0 3 1 0 3 3 3 0 Predicted coiled-coil domain-containing protein dCache_2 PF08269.11 KFR08217.1 - 1.9 7.6 7.7 0.15 11.2 2.1 2.0 2 0 0 2 2 2 0 Cache domain Chibby PF14645.6 KFR08217.1 - 2.2 8.7 7.4 5.4 7.4 2.5 3.1 2 1 0 2 2 2 0 Chibby family Lebercilin PF15619.6 KFR08217.1 - 2.5 7.7 32.1 2.6 7.6 13.9 3.9 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease GIT_CC PF16559.5 KFR08217.1 - 3.2 7.7 25.5 0.37 10.7 1.1 4.8 5 0 0 5 5 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor SlyX PF04102.12 KFR08217.1 - 3.9 8.2 28.8 1.9 9.1 0.3 5.2 4 1 1 5 5 5 0 SlyX Laminin_II PF06009.12 KFR08217.1 - 4.2 7.4 21.0 2.1 8.4 0.4 4.4 4 1 1 5 5 5 0 Laminin Domain II ZapB PF06005.12 KFR08217.1 - 4.3 7.8 34.2 0.73 10.3 4.2 4.8 3 1 2 5 5 4 0 Cell division protein ZapB DUF4164 PF13747.6 KFR08217.1 - 5.3 7.4 17.5 4.5 7.6 5.4 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4164) Syntaxin-6_N PF09177.11 KFR08217.1 - 5.5 7.6 14.2 9.7 6.8 0.8 4.3 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF2959 PF11172.8 KFR08217.1 - 5.7 7.0 11.3 2.4 8.3 7.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2959) FlaC_arch PF05377.11 KFR08217.1 - 8.3 6.9 15.2 29 5.2 0.1 5.1 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) DUF4686 PF15742.5 KFR08217.1 - 9 5.3 37.2 15 4.6 22.0 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4686) Phlebovirus_NSM PF07246.11 KFR08217.1 - 9.7 5.5 10.8 6.8 6.0 0.7 2.9 1 1 0 2 2 2 0 Phlebovirus nonstructural protein NS-M bZIP_1 PF00170.21 KFR08217.1 - 9.9 6.3 20.1 0.39 10.9 1.4 4.9 4 0 0 4 4 4 0 bZIP transcription factor EPTP PF03736.17 KFR08218.1 - 1.1e-70 233.4 22.2 5.3e-13 48.7 0.1 7.3 7 0 0 7 7 7 7 EPTP domain LRR_8 PF13855.6 KFR08218.1 - 4.8e-23 80.7 8.7 5.8e-14 51.6 2.0 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFR08218.1 - 1.7e-08 34.6 3.1 0.00047 20.5 0.6 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFR08218.1 - 6.6e-08 32.6 0.2 4e-07 30.0 0.0 2.2 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFR08218.1 - 0.00042 19.9 0.3 0.02 14.4 0.1 1.7 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFR08218.1 - 0.005 17.2 5.7 41 5.3 0.0 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat SepSecS PF05889.13 KFR08219.1 - 9.4e-179 594.1 0.0 1.1e-178 593.9 0.0 1.0 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 KFR08219.1 - 3.2e-05 23.4 0.0 7.8e-05 22.1 0.0 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 KFR08219.1 - 0.063 12.0 0.1 0.38 9.4 0.0 2.0 1 1 1 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain PI3_PI4_kinase PF00454.27 KFR08220.1 - 3.7e-67 226.8 0.0 4.4e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase N6-adenineMlase PF10237.9 KFR08221.1 - 1.4e-20 73.7 0.8 2.6e-20 72.9 0.8 1.4 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase zf-GRF PF06839.12 KFR08221.1 - 1.5e-13 50.6 2.2 1.5e-13 50.6 2.2 2.8 2 1 0 2 2 2 1 GRF zinc finger RNA_POL_M_15KD PF02150.16 KFR08221.1 - 0.031 14.2 0.3 0.031 14.2 0.3 5.6 4 1 2 6 6 6 0 RNA polymerases M/15 Kd subunit ANAPC4 PF12896.7 KFR08222.1 - 3.5e-57 193.2 11.2 5.6e-57 192.5 11.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KFR08222.1 - 5.7e-26 90.6 0.0 1.3e-25 89.5 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Na_Pi_cotrans PF02690.15 KFR08223.1 - 8.9e-41 139.3 19.9 8.3e-25 87.5 6.2 2.6 2 0 0 2 2 2 2 Na+/Pi-cotransporter Sel1 PF08238.12 KFR08224.1 - 1.5e-21 76.3 32.3 0.00013 22.6 0.1 8.6 8 0 0 8 8 8 6 Sel1 repeat BTD PF09270.10 KFR08226.1 - 1.4e-75 252.7 0.0 2.2e-75 252.0 0.0 1.3 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.11 KFR08226.1 - 2.4e-50 171.1 0.7 5.9e-50 169.8 0.7 1.7 1 0 0 1 1 1 1 LAG1, DNA binding TIG PF01833.24 KFR08226.1 - 1.6e-05 24.9 1.2 0.00042 20.4 0.0 2.6 2 0 0 2 2 2 1 IPT/TIG domain RHD_dimer PF16179.5 KFR08226.1 - 0.017 15.1 0.0 0.071 13.1 0.0 2.2 1 1 0 1 1 1 0 Rel homology dimerisation domain 7tm_1 PF00001.21 KFR08227.1 - 2.6e-62 210.5 17.1 4.1e-62 209.9 17.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CholecysA-Rec_N PF09193.10 KFR08227.1 - 2.6e-28 97.7 0.4 6.3e-28 96.5 0.4 1.7 1 0 0 1 1 1 1 Cholecystokinin A receptor, N-terminal 7tm_4 PF13853.6 KFR08227.1 - 2.4e-10 40.6 8.9 2.4e-10 40.6 8.9 1.7 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KFR08227.1 - 6.7e-08 32.2 24.3 4e-07 29.7 24.3 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4834 PF16118.5 KFR08227.1 - 6.3 7.8 0.0 6.3 7.8 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) RabGAP-TBC PF00566.18 KFR08228.1 - 6.2e-15 55.4 6.8 1.4e-12 47.8 2.5 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain SOAR PF16533.5 KFR08229.1 - 1.2e-40 137.5 3.9 1.2e-40 137.5 3.9 3.0 2 1 1 3 3 3 1 STIM1 Orai1-activating region SAM_2 PF07647.17 KFR08229.1 - 3.2e-12 46.4 0.1 8.3e-12 45.0 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFR08229.1 - 3.9e-07 30.4 0.1 1.2e-06 28.8 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF4446 PF14584.6 KFR08229.1 - 0.34 10.9 4.6 0.086 12.8 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) ESSS PF10183.9 KFR08229.1 - 0.4 10.9 0.0 0.4 10.9 0.0 2.9 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Orbi_NS3 PF01616.16 KFR08229.1 - 0.79 9.4 3.3 2.1 8.0 0.1 2.3 2 0 0 2 2 2 0 Orbivirus NS3 DEP PF00610.21 KFR08239.1 - 2.4e-16 59.5 0.1 3.1e-15 56.0 0.0 2.5 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.27 KFR08239.1 - 2.1e-07 30.9 0.4 7.9e-07 29.0 0.1 2.2 2 0 0 2 2 2 1 RhoGAP domain ELO PF01151.18 KFR08240.1 - 2.6e-59 200.8 25.7 3e-59 200.6 25.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family UT PF03253.14 KFR08242.1 - 1.5e-98 329.5 26.9 1.7e-98 329.4 26.9 1.0 1 0 0 1 1 1 1 Urea transporter VWD PF00094.25 KFR08243.1 - 8.8e-33 113.8 2.4 8.8e-33 113.8 2.4 1.9 2 0 0 2 2 2 1 von Willebrand factor type D domain C8 PF08742.11 KFR08243.1 - 6.6e-19 68.1 16.7 6.6e-19 68.1 16.7 2.1 2 0 0 2 2 2 1 C8 domain TIL PF01826.17 KFR08243.1 - 0.0014 18.9 5.4 0.0014 18.9 5.4 4.9 3 1 0 3 3 3 1 Trypsin Inhibitor like cysteine rich domain VWD PF00094.25 KFR08244.1 - 2.4e-25 89.6 0.5 2.4e-25 89.6 0.5 1.7 2 0 0 2 2 2 1 von Willebrand factor type D domain C8 PF08742.11 KFR08244.1 - 6.4e-19 68.2 13.1 6.4e-19 68.2 13.1 2.4 2 0 0 2 2 2 1 C8 domain VWC PF00093.18 KFR08244.1 - 1.8e-06 28.2 6.7 1.8e-06 28.2 6.7 4.1 3 1 1 4 4 4 1 von Willebrand factor type C domain TIL PF01826.17 KFR08244.1 - 1.4e-05 25.2 4.1 1.4e-05 25.2 4.1 4.8 3 1 0 3 3 3 1 Trypsin Inhibitor like cysteine rich domain Pacifastin_I PF05375.13 KFR08244.1 - 0.016 14.9 16.1 0.016 14.9 16.1 3.6 4 0 0 4 4 4 0 Pacifastin inhibitor (LCMII) VWD PF00094.25 KFR08245.1 - 7.8e-35 120.5 3.5 7.8e-35 120.5 3.5 2.6 3 1 0 3 3 3 1 von Willebrand factor type D domain C8 PF08742.11 KFR08245.1 - 1.1e-16 60.9 3.0 1.1e-16 60.9 3.0 5.4 5 1 1 6 6 6 1 C8 domain Cys_knot PF00007.22 KFR08245.1 - 3.4e-10 40.1 16.2 3.4e-10 40.1 16.2 6.3 5 1 2 7 7 7 1 Cystine-knot domain TIL PF01826.17 KFR08245.1 - 0.00046 20.4 12.2 0.00046 20.4 12.2 10.9 6 3 4 10 10 10 1 Trypsin Inhibitor like cysteine rich domain VWC PF00093.18 KFR08245.1 - 0.0024 18.1 15.0 0.0024 18.1 15.0 9.0 5 2 2 7 7 7 4 von Willebrand factor type C domain Pkinase_Tyr PF07714.17 KFR08315.1 - 8.6e-106 353.0 0.0 1.3e-105 352.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR08315.1 - 7e-42 143.6 0.1 8.4e-29 100.7 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain I-set PF07679.16 KFR08315.1 - 4.4e-34 116.4 1.3 1.9e-19 69.5 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR08315.1 - 2.4e-29 101.7 7.2 1.7e-14 54.2 0.1 3.5 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFR08315.1 - 5.2e-24 84.2 4.0 1.4e-11 44.4 0.7 3.7 3 1 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KFR08315.1 - 2.2e-22 79.2 3.8 1.9e-10 41.0 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain VEGFR-2_TMD PF17988.1 KFR08315.1 - 3.4e-18 64.8 0.7 7.7e-18 63.6 0.7 1.6 1 0 0 1 1 1 1 VEGFR-2 Transmembrane domain V-set PF07686.17 KFR08315.1 - 4.6e-13 49.3 6.9 3.5e-05 23.9 0.9 5.2 3 2 1 4 4 4 2 Immunoglobulin V-set domain Ig_4 PF16680.5 KFR08315.1 - 5.9e-09 36.1 0.9 0.00075 19.7 0.0 3.4 3 0 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFR08315.1 - 4.2e-08 33.5 2.5 0.0014 18.9 0.0 3.7 3 0 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFR08315.1 - 0.00013 21.5 0.0 2.1 8.0 0.0 3.4 3 0 0 3 3 3 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFR08315.1 - 0.00081 19.4 0.6 2.5 8.2 0.1 3.4 4 0 0 4 4 4 2 Izumo-like Immunoglobulin domain Adeno_E3_CR1 PF02440.15 KFR08315.1 - 0.0014 18.4 2.0 0.11 12.3 0.4 3.3 3 0 0 3 3 3 1 Adenovirus E3 region protein CR1 Haspin_kinase PF12330.8 KFR08315.1 - 0.0052 15.8 0.1 0.022 13.7 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Ig_C17orf99 PF17736.1 KFR08315.1 - 0.0087 16.1 0.2 17 5.5 0.0 3.5 3 0 0 3 3 3 0 C17orf99 Ig domain C2-set_2 PF08205.12 KFR08315.1 - 0.011 15.7 0.1 0.052 13.6 0.0 2.1 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain ADH_N PF08240.12 KFR08315.1 - 0.053 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Herpes_gE PF02480.16 KFR08315.1 - 0.084 11.6 0.1 6.7 5.3 0.0 2.5 1 1 0 2 2 2 0 Alphaherpesvirus glycoprotein E PMC2NT PF08066.12 KFR08315.1 - 0.11 13.2 0.3 0.31 11.8 0.3 1.7 1 0 0 1 1 1 0 PMC2NT (NUC016) domain RhoGEF PF00621.20 KFR08316.1 - 8.1e-44 150.0 2.4 8.1e-44 150.0 2.4 1.9 2 1 0 2 2 2 1 RhoGEF domain SH3_1 PF00018.28 KFR08316.1 - 1.9e-10 40.2 1.8 3.9e-10 39.2 1.8 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFR08316.1 - 1.2e-09 37.7 0.0 2.9e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFR08316.1 - 3.6e-09 36.3 0.1 7.5e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 KFR08316.1 - 3.2e-07 30.8 0.3 6.9e-07 29.7 0.3 1.5 1 0 0 1 1 1 1 PH domain WTX PF09422.10 KFR08318.1 - 4.1e-72 243.8 19.1 2.9e-31 109.1 0.9 3.0 1 1 2 3 3 3 3 WTX protein Ank_2 PF12796.7 KFR08319.1 - 1.8e-27 95.7 2.0 3.2e-11 43.6 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFR08319.1 - 6.1e-23 78.4 0.5 0.00023 21.3 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 KFR08319.1 - 1.3e-21 76.0 1.5 0.0053 17.1 0.1 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KFR08319.1 - 1.6e-18 66.8 0.3 1.6e-08 34.9 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFR08319.1 - 8.9e-17 60.9 0.7 5.9e-05 23.3 0.0 4.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFR08319.1 - 1.8e-05 25.0 0.7 1.8e-05 25.0 0.7 1.8 2 0 0 2 2 2 1 SOCS box Myotub-related PF06602.14 KFR08320.1 - 6.8e-146 485.7 0.0 9.1e-146 485.3 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 KFR08320.1 - 0.00042 20.0 0.0 0.00084 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase GRAM PF02893.20 KFR08320.1 - 0.00092 19.1 0.0 0.0025 17.7 0.0 1.7 2 0 0 2 2 2 1 GRAM domain Y_phosphatase2 PF03162.13 KFR08320.1 - 0.0018 17.9 0.1 0.15 11.6 0.1 2.5 2 0 0 2 2 2 1 Tyrosine phosphatase family Vps36_ESCRT-II PF11605.8 KFR08320.1 - 0.0022 18.1 0.1 0.0038 17.4 0.1 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 DSPc PF00782.20 KFR08320.1 - 0.0032 17.3 0.1 0.018 14.8 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFR08320.1 - 0.0093 16.0 0.1 0.028 14.4 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family Shisa PF13908.6 KFR08321.1 - 2e-36 126.1 0.2 2.8e-36 125.6 0.2 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM52 PF14979.6 KFR08321.1 - 2.3 8.1 10.8 0.061 13.2 1.0 2.2 2 1 0 2 2 2 0 Transmembrane 52 DUF4606 PF15379.6 KFR08322.1 - 6.9e-32 109.8 0.4 7.5e-32 109.7 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4606) Gtr1_RagA PF04670.12 KFR08323.1 - 3.4e-108 360.4 1.2 4.1e-108 360.1 1.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KFR08323.1 - 3e-08 33.9 0.0 1.1e-07 32.1 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFR08323.1 - 3.5e-08 33.2 0.0 8e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KFR08323.1 - 2.6e-07 30.3 0.1 6.5e-07 29.0 0.0 1.5 1 1 1 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFR08323.1 - 9.3e-07 28.9 0.0 3.1e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFR08323.1 - 0.0015 18.1 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFR08323.1 - 0.024 14.1 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF815 PF05673.13 KFR08323.1 - 0.031 13.4 1.7 0.47 9.6 0.5 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF815) SecA_DEAD PF07517.14 KFR08323.1 - 0.051 12.9 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain RsgA_GTPase PF03193.16 KFR08323.1 - 0.15 12.0 0.2 10 6.0 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KFR08323.1 - 0.18 12.3 0.1 0.31 11.6 0.1 1.7 1 1 0 1 1 1 0 ABC transporter DUF5099 PF17025.5 KFR08323.1 - 2.7 8.4 6.0 18 5.8 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5099) zf-C2H2 PF00096.26 KFR08324.1 - 3.6e-11 42.9 10.4 2.7e-06 27.5 3.9 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFR08324.1 - 2.9e-08 33.8 1.2 2.9e-08 33.8 1.2 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR08324.1 - 7.1e-06 26.4 8.6 0.009 16.8 1.8 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFR08324.1 - 0.13 12.3 0.8 0.3 11.1 0.8 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger DUF3850 PF12961.7 KFR08324.1 - 0.19 11.8 0.0 0.29 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) zf-H2C2_5 PF13909.6 KFR08324.1 - 3.5 7.5 9.8 0.76 9.6 2.3 2.9 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFR08325.1 - 3.1e-14 52.5 25.4 4.4e-05 23.7 0.6 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFR08325.1 - 1.8e-09 37.6 10.8 1.1e-05 25.6 3.5 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR08325.1 - 2.1e-06 28.1 23.4 0.044 14.6 4.1 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFR08325.1 - 0.0075 16.9 5.9 0.35 11.5 0.2 2.5 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 KFR08325.1 - 0.15 11.8 5.3 0.086 12.6 2.7 2.0 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 KFR08325.1 - 1.8 8.7 5.6 17 5.5 2.0 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger BTB_2 PF02214.22 KFR08326.1 - 1e-14 54.7 0.0 1.9e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KFR08326.1 - 0.011 15.8 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Sec3_C PF09763.9 KFR08327.1 - 1.1e-78 265.4 4.2 1.4e-78 265.0 4.2 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Helicase_C_4 PF13871.6 KFR08327.1 - 0.045 13.4 0.2 12 5.4 0.2 2.6 2 1 1 3 3 3 0 C-terminal domain on Strawberry notch homologue Glyoxalase PF00903.25 KFR08328.1 - 2e-10 41.0 0.0 3.6e-09 36.9 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 KFR08328.1 - 0.0039 17.1 0.1 2.7 7.9 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KFR08328.1 - 0.021 15.0 0.0 0.033 14.3 0.0 1.4 1 1 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KFR08328.1 - 0.052 13.8 0.0 0.1 12.9 0.0 1.7 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MmgE_PrpD PF03972.14 KFR08329.1 - 3.9e-126 421.1 0.0 4.4e-126 421.0 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DJ-1_PfpI PF01965.24 KFR08330.1 - 0.00018 21.3 1.5 0.00045 20.0 1.5 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family DUF587 PF04532.12 KFR08330.1 - 0.037 13.3 0.1 0.056 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF587) EF-hand_1 PF00036.32 KFR08331.1 - 6e-31 103.7 17.2 1.2e-08 33.9 0.8 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFR08331.1 - 2.2e-28 98.5 9.2 3.1e-14 53.2 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFR08331.1 - 9.2e-24 81.3 10.6 2.2e-08 33.3 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KFR08331.1 - 2.7e-23 81.6 14.0 7.1e-12 45.0 0.7 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 KFR08331.1 - 9.2e-17 61.1 0.3 4.1e-07 30.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFR08331.1 - 4.1e-09 35.5 17.6 0.0033 16.9 1.2 4.6 4 1 1 5 5 5 3 EF hand EF-hand_4 PF12763.7 KFR08331.1 - 7e-07 29.2 6.4 0.053 13.5 0.0 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 KFR08331.1 - 2.4e-05 24.6 1.8 0.17 12.3 0.3 2.6 1 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KFR08331.1 - 0.0034 17.7 2.0 0.81 10.0 0.5 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF853 PF05872.12 KFR08331.1 - 0.0041 15.8 0.6 0.019 13.6 0.3 1.8 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF853) Dockerin_1 PF00404.18 KFR08331.1 - 0.0041 17.3 0.3 0.26 11.5 0.1 2.5 2 1 0 2 2 2 1 Dockerin type I domain EF-hand_11 PF08976.11 KFR08331.1 - 0.0091 16.9 0.3 1.4 9.8 0.1 2.1 1 1 1 2 2 2 1 EF-hand domain SurA_N_3 PF13624.6 KFR08331.1 - 0.011 15.5 3.7 0.38 10.5 0.7 2.2 1 1 1 2 2 2 0 SurA N-terminal domain SUB1_ProdP9 PF18213.1 KFR08331.1 - 0.035 13.9 2.1 0.049 13.5 0.4 1.9 1 1 1 2 2 2 0 SUB1 protease Prodomain ProdP9 Sigma54_CBD PF04963.13 KFR08331.1 - 0.036 13.9 0.5 0.049 13.5 0.5 1.1 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain SurA_N_2 PF13623.6 KFR08331.1 - 0.044 13.6 4.5 1 9.2 0.2 2.8 1 1 2 3 3 3 0 SurA N-terminal domain DUF1542 PF07564.11 KFR08331.1 - 0.39 10.9 4.9 8.6 6.6 0.3 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) Gp-FAR-1 PF05823.12 KFR08331.1 - 0.4 11.0 0.2 0.4 11.0 0.2 3.1 1 1 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) SRI PF08236.11 KFR08331.1 - 0.93 9.7 7.6 1 9.6 0.1 3.3 2 1 1 3 3 3 0 SRI (Set2 Rpb1 interacting) domain DUF2757 PF10955.8 KFR08331.1 - 1.7 9.0 4.1 4.9 7.5 0.4 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF2757) 3Beta_HSD PF01073.19 KFR08332.1 - 7.3e-68 228.6 0.0 8.9e-68 228.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFR08332.1 - 1.3e-35 123.0 0.0 1.7e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFR08332.1 - 2.4e-19 69.9 0.0 1.3e-17 64.2 0.0 2.4 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KFR08332.1 - 4e-15 56.2 0.0 5.2e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KFR08332.1 - 2.1e-12 46.7 0.0 3e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KFR08332.1 - 1.7e-08 34.0 0.0 0.00098 18.4 0.0 2.4 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KFR08332.1 - 3.9e-08 32.8 0.0 7.3e-07 28.6 0.0 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KFR08332.1 - 2e-07 30.8 0.0 3.3e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_2 PF03446.15 KFR08332.1 - 0.016 15.4 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.10 KFR08332.1 - 0.044 13.7 0.2 1.1 9.1 0.0 2.2 1 1 0 2 2 2 0 KR domain 3HCDH_N PF02737.18 KFR08332.1 - 0.086 12.7 0.0 0.13 12.1 0.0 1.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SLAIN PF15301.6 KFR08333.1 - 9.9e-137 456.7 60.9 2.5e-116 389.5 55.2 2.3 1 1 1 2 2 2 2 SLAIN motif-containing family Synaptobrevin PF00957.21 KFR08334.1 - 1.9e-28 98.0 2.8 3e-28 97.4 2.8 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KFR08334.1 - 2.6e-27 94.7 0.7 4.8e-27 93.8 0.7 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain RIFIN PF02009.16 KFR08334.1 - 0.0085 16.0 1.3 0.011 15.7 1.3 1.2 1 0 0 1 1 1 1 Rifin Pox_EPC_I2-L1 PF12575.8 KFR08334.1 - 1.3 9.3 7.6 0.89 9.8 2.2 2.8 2 1 1 3 3 3 0 Poxvirus entry protein complex L1 and I2 RNA_pol_L_2 PF13656.6 KFR08335.1 - 3.2e-29 100.5 0.0 3.7e-29 100.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KFR08335.1 - 3.3e-13 48.9 0.0 4.2e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain 7tm_1 PF00001.21 KFR08336.1 - 1e-35 123.3 13.0 1.4e-35 122.9 13.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR08336.1 - 0.0003 20.3 13.5 0.0028 17.1 13.5 2.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFR08336.1 - 0.099 12.4 9.1 0.13 12.0 9.1 1.3 1 0 0 1 1 1 0 Olfactory receptor LEP503 PF15221.6 KFR08336.1 - 0.12 12.7 2.8 0.34 11.2 2.8 1.8 1 0 0 1 1 1 0 Lens epithelial cell protein LEP503 Sprouty PF05210.13 KFR08337.1 - 3.8e-25 88.3 32.1 7.4e-25 87.3 32.1 1.5 1 0 0 1 1 1 1 Sprouty protein (Spry) TauD PF02668.16 KFR08338.1 - 4.4e-39 134.9 0.1 6.3e-39 134.4 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KFR08338.1 - 4.5e-13 49.6 0.1 8.9e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KFR08338.1 - 0.00092 18.4 0.0 0.0048 16.1 0.0 1.9 2 0 0 2 2 2 1 CsiD V-set PF07686.17 KFR08339.1 - 7.1e-06 26.2 0.0 3.7e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin V-set domain V-set PF07686.17 KFR08340.1 - 2.7e-05 24.3 0.0 0.00015 21.9 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFR08341.1 - 5.4e-14 52.0 0.0 1.6e-09 37.7 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR08341.1 - 3.1e-13 50.1 0.2 8.5e-09 35.9 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFR08341.1 - 5.7e-12 45.8 0.0 2.2e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 KFR08341.1 - 7.7e-07 29.4 0.1 2.2e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 KFR08341.1 - 5e-05 23.4 0.1 0.035 14.3 0.1 2.4 2 1 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 KFR08341.1 - 0.0062 16.1 0.0 0.61 9.7 0.1 2.3 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFR08342.1 - 1.4e-11 44.3 0.0 1.1e-09 38.2 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR08342.1 - 3e-10 40.5 0.2 3.1e-08 34.1 0.1 2.2 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFR08342.1 - 3.7e-09 36.7 0.2 9.3e-05 22.6 0.0 3.0 2 1 1 3 3 3 2 Immunoglobulin V-set domain Ig_2 PF13895.6 KFR08342.1 - 5.7e-09 36.2 0.1 2.2e-06 27.9 0.2 2.2 1 1 1 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFR08342.1 - 0.00031 20.9 0.1 0.06 13.5 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Receptor_2B4 PF11465.8 KFR08342.1 - 0.011 16.0 0.2 3.6 7.8 0.0 2.9 2 1 1 3 3 3 0 Natural killer cell receptor 2B4 Ig_5 PF16681.5 KFR08342.1 - 0.029 14.8 0.0 0.12 12.8 0.0 2.1 2 1 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain TNF PF00229.18 KFR08343.1 - 2.3e-38 131.0 0.1 3.9e-38 130.2 0.1 1.4 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Voltage_CLC PF00654.20 KFR08344.1 - 3.7e-108 361.9 22.3 3.7e-108 361.9 22.3 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KFR08344.1 - 7.3e-15 55.2 2.5 2e-06 28.2 0.1 2.5 2 0 0 2 2 2 2 CBS domain RGCC PF15151.6 KFR08345.1 - 4.9e-44 149.9 1.1 5.4e-44 149.7 1.1 1.0 1 0 0 1 1 1 1 Response gene to complement 32 protein family DUF4769 PF15992.5 KFR08345.1 - 0.14 12.0 0.1 0.2 11.4 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4769) Mst1_SARAH PF11629.8 KFR08345.1 - 6.5 6.9 7.9 21 5.3 0.2 3.4 4 0 0 4 4 4 0 C terminal SARAH domain of Mst1 RhoGAP PF00620.27 KFR08346.1 - 1.2e-41 142.1 0.0 5e-41 140.0 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain RRM_1 PF00076.22 KFR08347.1 - 1e-07 31.6 0.0 2.4e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFR08347.1 - 0.016 15.3 0.1 0.25 11.5 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif APC_N_CC PF16689.5 KFR08347.1 - 0.052 13.6 0.6 0.052 13.6 0.6 3.1 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain 7tm_1 PF00001.21 KFR08348.1 - 5.5e-40 137.4 7.5 6.7e-40 137.1 7.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFR08348.1 - 0.051 13.3 6.5 0.12 12.1 6.5 1.7 1 1 0 1 1 1 0 Olfactory receptor zf-LITAF-like PF10601.9 KFR08348.1 - 5.9 7.2 8.2 11 6.3 0.4 3.7 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain Mito_carr PF00153.27 KFR08349.1 - 2.1e-47 159.0 0.3 1.1e-21 76.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.22 KFR08350.1 - 2.2e-15 56.2 0.1 3.9e-15 55.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1314 PF07013.11 KFR08350.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) Ras PF00071.22 KFR08351.1 - 1.3e-48 164.6 0.0 1.5e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR08351.1 - 9.6e-32 109.7 0.0 1.3e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR08351.1 - 2.1e-14 53.3 0.0 2.4e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFR08351.1 - 3.1e-08 33.3 0.0 3.9e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFR08351.1 - 8.2e-08 32.3 0.0 1.1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFR08351.1 - 3e-05 23.5 0.0 5.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KFR08351.1 - 0.0021 17.7 0.7 0.091 12.3 0.7 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 KFR08351.1 - 0.0022 17.2 0.3 0.0041 16.3 0.3 1.7 1 1 0 1 1 1 1 G-protein alpha subunit PduV-EutP PF10662.9 KFR08351.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 KFR08351.1 - 0.08 12.5 0.1 0.14 11.7 0.1 1.5 1 1 0 1 1 1 0 Ferrous iron transport protein B tRNA-synt_1g PF09334.11 KFR08352.1 - 6.1e-88 295.2 0.0 2.5e-87 293.2 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KFR08352.1 - 4.6e-13 48.3 0.2 1.1e-10 40.4 0.0 2.9 1 1 2 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KFR08352.1 - 8.3e-06 25.8 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KFR08352.1 - 5e-05 22.8 0.0 7.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain EB1 PF03271.17 KFR08356.1 - 3.1e-18 65.7 0.4 8.5e-18 64.3 0.2 1.9 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.31 KFR08356.1 - 3e-15 56.3 0.4 4.3e-15 55.8 0.4 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFR08356.1 - 0.012 15.4 0.1 0.028 14.2 0.1 1.5 1 0 0 1 1 1 0 CAMSAP CH domain CH_2 PF06294.11 KFR08356.1 - 0.075 13.2 0.1 0.13 12.4 0.0 1.4 1 1 0 1 1 1 0 CH-like domain in sperm protein EGF_3 PF12947.7 KFR08357.1 - 0.12 12.6 2.9 0.26 11.5 3.0 1.5 1 1 0 1 1 1 0 EGF domain Amidohydro_1 PF01979.20 KFR08358.1 - 3.1e-22 79.4 1.0 4.9e-22 78.7 1.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFR08358.1 - 2.3e-11 43.8 3.2 1e-05 25.2 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family TIR-like PF10137.9 KFR08358.1 - 0.05 13.5 0.0 0.75 9.8 0.0 2.3 2 0 0 2 2 2 0 Predicted nucleotide-binding protein containing TIR-like domain AP_endonuc_2 PF01261.24 KFR08358.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel SNAP PF14938.6 KFR08359.1 - 4.4e-104 347.9 20.6 4.9e-104 347.7 20.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KFR08359.1 - 1.1e-07 32.0 13.0 0.0027 18.0 0.7 3.6 1 1 3 4 4 4 4 Tetratricopeptide repeat NSF PF02071.20 KFR08359.1 - 1.9e-05 24.5 36.8 0.52 11.3 2.7 9.1 8 2 1 9 9 9 2 Aromatic-di-Alanine (AdAR) repeat TPR_7 PF13176.6 KFR08359.1 - 0.0002 21.1 9.0 0.14 12.2 0.0 5.2 5 1 1 6 6 5 2 Tetratricopeptide repeat Spatacsin_C PF14649.6 KFR08359.1 - 0.0024 17.1 12.9 0.0074 15.4 2.9 2.7 1 1 2 3 3 3 2 Spatacsin C-terminus TPR_10 PF13374.6 KFR08359.1 - 0.015 15.2 7.5 6.1 6.9 0.1 4.8 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFR08359.1 - 0.032 14.4 18.1 3.2 8.2 0.3 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFR08359.1 - 0.035 14.9 3.5 55 5.0 0.0 4.8 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFR08359.1 - 0.053 13.7 17.2 4.6 7.6 0.3 5.3 4 1 3 7 7 6 0 Tetratricopeptide repeat DUF4368 PF14287.6 KFR08359.1 - 0.056 13.8 0.2 3.5 8.0 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4368) TPR_16 PF13432.6 KFR08359.1 - 0.11 13.2 5.4 1.1 9.9 1.0 3.9 2 1 2 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFR08359.1 - 0.24 12.1 13.3 2.3 9.0 0.3 5.6 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFR08359.1 - 0.37 10.5 11.9 3.6 7.3 0.5 4.6 4 0 0 4 4 4 0 TPR repeat TPR_1 PF00515.28 KFR08359.1 - 1 9.3 19.2 2.4 8.1 0.1 4.8 5 1 0 5 5 4 0 Tetratricopeptide repeat RPN7 PF10602.9 KFR08359.1 - 1.1 8.9 8.5 1.2 8.9 2.9 2.7 1 1 2 3 3 3 0 26S proteasome subunit RPN7 Sel1 PF08238.12 KFR08359.1 - 2 9.2 0.1 2 9.2 0.1 3.7 5 0 0 5 5 3 0 Sel1 repeat TPR_3 PF07720.12 KFR08359.1 - 8.1 6.6 10.9 33 4.6 1.5 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat EHD_N PF16880.5 KFR08361.1 - 1.1e-17 63.5 3.1 1.9e-17 62.9 3.1 1.4 1 0 0 1 1 1 1 N-terminal EH-domain containing protein DUF5600 PF18150.1 KFR08361.1 - 1.7e-17 64.0 0.1 8.9e-17 61.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5600) Dynamin_N PF00350.23 KFR08361.1 - 1.2e-09 38.5 0.0 6e-07 29.7 0.0 2.1 2 0 0 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 KFR08361.1 - 0.00094 19.3 0.0 0.14 12.2 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 KFR08361.1 - 0.00097 19.3 0.0 0.93 9.7 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KFR08361.1 - 0.005 16.4 0.0 0.42 10.1 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Septin PF00735.18 KFR08361.1 - 0.063 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_28 PF13521.6 KFR08361.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFR08361.1 - 0.12 12.8 0.0 0.32 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KFR08361.1 - 0.13 12.5 0.1 0.6 10.4 0.0 2.0 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 KFR08361.1 - 0.17 11.5 0.0 16 5.1 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Vps4_C PF09336.10 KFR08362.1 - 2e-12 46.9 1.4 3.5e-12 46.1 1.4 1.4 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 KFR08362.1 - 4e-10 39.3 0.0 7.7e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 KFR08362.1 - 0.00018 22.0 0.0 0.00032 21.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arb2 PF09757.9 KFR08363.1 - 2.3e-10 40.1 1.5 1.6e-07 30.8 1.5 2.2 1 1 0 1 1 1 1 Arb2 domain Hydrolase_4 PF12146.8 KFR08363.1 - 0.0034 16.7 0.0 0.0063 15.8 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 WGG PF10273.9 KFR08363.1 - 0.1 13.3 0.0 2.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Pre-rRNA-processing protein TSR2 BAR_3 PF16746.5 KFR08438.1 - 6.4e-47 160.3 19.4 5.9e-40 137.5 13.1 2.3 1 1 1 2 2 2 2 BAR domain of APPL family RhoGAP PF00620.27 KFR08438.1 - 1.4e-40 138.6 0.3 7.9e-40 136.2 0.1 2.2 2 0 0 2 2 2 1 RhoGAP domain SH3_9 PF14604.6 KFR08438.1 - 8.2e-09 35.2 0.0 1.7e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFR08438.1 - 1.2e-05 24.8 0.0 2.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFR08438.1 - 0.062 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain Hormone_recep PF00104.30 KFR08439.1 - 6.7e-28 97.7 7.3 1.1e-27 97.0 7.3 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFR08439.1 - 1.1e-26 93.0 15.7 1.1e-26 93.0 15.7 1.6 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Prog_receptor PF02161.15 KFR08439.1 - 0.0035 16.1 0.8 0.0046 15.8 0.8 1.1 1 0 0 1 1 1 1 Progesterone receptor DUF1422 PF07226.11 KFR08439.1 - 0.12 12.4 0.2 16 5.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) Steroid_dh PF02544.16 KFR08526.1 - 2.2e-19 69.9 6.7 2.2e-19 69.9 6.7 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Pkinase_Tyr PF07714.17 KFR08527.1 - 7.1e-100 333.6 0.0 8.3e-100 333.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR08527.1 - 1.7e-49 168.6 0.0 2e-49 168.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.6 KFR08527.1 - 1.3e-15 58.0 0.3 2.4e-15 57.2 0.3 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Haspin_kinase PF12330.8 KFR08527.1 - 0.0033 16.4 0.0 0.0051 15.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFR08527.1 - 0.0097 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFR08527.1 - 0.032 13.0 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SH2 PF00017.24 KFR08528.1 - 2.6e-05 24.2 0.0 5.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 SH2 domain PH PF00169.29 KFR08528.1 - 3.7e-05 24.2 0.1 6.5e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFR08528.1 - 0.012 16.0 0.1 0.028 14.8 0.1 1.7 1 1 0 1 1 1 0 Pleckstrin homology domain ThiF PF00899.21 KFR08529.1 - 3.1e-96 321.5 0.0 3.2e-64 216.6 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KFR08529.1 - 3.5e-80 269.6 1.6 5.5e-80 268.9 1.6 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 KFR08529.1 - 8e-26 90.0 0.0 1.8e-25 88.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 KFR08529.1 - 5.4e-16 58.5 0.3 2.2e-15 56.6 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_UFD PF09358.10 KFR08529.1 - 2.1e-14 54.0 0.0 5.8e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin fold domain Trypsin PF00089.26 KFR08531.1 - 1.4e-32 113.3 0.0 3.2e-32 112.1 0.0 1.4 1 1 0 1 1 1 1 Trypsin YTH PF04146.15 KFR08533.1 - 2.3e-41 141.5 0.1 2.3e-41 141.5 0.1 3.8 2 2 0 2 2 2 1 YT521-B-like domain UDPGT PF00201.18 KFR08534.1 - 7.5e-222 737.5 0.1 8.4e-222 737.4 0.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KFR08534.1 - 1.3e-06 28.5 0.0 2.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Pro_3_hydrox_C PF05373.11 KFR08534.1 - 0.00098 19.2 0.0 0.0025 17.9 0.0 1.6 1 0 0 1 1 1 1 L-proline 3-hydroxylase, C-terminal Glyco_transf_4 PF13439.6 KFR08534.1 - 0.073 13.1 0.0 0.67 9.9 0.0 2.3 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Sulfotransfer_1 PF00685.27 KFR08535.1 - 6.7e-85 284.8 0.0 7.7e-85 284.6 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFR08535.1 - 5.4e-06 27.0 0.3 0.011 16.1 0.1 2.3 2 0 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 KFR08536.1 - 8.6e-76 254.9 0.0 1.4e-75 254.2 0.0 1.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFR08536.1 - 0.1 13.0 0.1 2.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Sulfotransferase family Sulfotransfer_1 PF00685.27 KFR08537.1 - 2e-92 309.5 0.2 2.2e-92 309.3 0.2 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFR08537.1 - 1.4e-11 45.2 0.0 3.8e-08 34.0 0.0 2.4 2 0 0 2 2 2 2 Sulfotransferase family HTH_Tnp_Tc3_2 PF01498.18 KFR08537.1 - 0.00049 20.3 0.0 0.00088 19.5 0.0 1.3 1 0 0 1 1 1 1 Transposase B5 PF03484.15 KFR08537.1 - 0.11 12.8 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetase B5 domain DnaG_DnaB_bind PF08278.11 KFR08537.1 - 0.13 12.9 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding DUF4576 PF15144.6 KFR08537.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) SH2 PF00017.24 KFR08538.1 - 1.8e-13 50.4 0.7 2.8e-13 49.8 0.1 1.7 2 0 0 2 2 2 1 SH2 domain BDV_P10 PF06515.11 KFR08538.1 - 0.74 9.9 4.4 0.2 11.7 1.2 1.7 2 0 0 2 2 2 0 Borna disease virus P10 protein CHGN PF05679.16 KFR08539.1 - 6.5e-74 249.6 1.1 8.4e-74 249.2 1.1 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 KFR08539.1 - 3.6e-09 36.2 1.2 8.3e-09 35.0 1.2 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KFR08539.1 - 0.00016 21.3 0.9 0.00061 19.3 0.9 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KFR08539.1 - 0.0041 16.9 0.0 0.0081 16.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF4094 PF13334.6 KFR08539.1 - 0.035 14.5 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Cnn_1N PF07989.11 KFR08539.1 - 0.69 10.1 7.2 0.37 11.0 1.9 2.9 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 Mod_r PF07200.13 KFR08539.1 - 0.74 9.9 5.9 0.2 11.8 2.5 1.7 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Csm1_N PF18504.1 KFR08539.1 - 1.9 8.9 7.1 0.74 10.2 3.4 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain TPR_19 PF14559.6 KFR08540.1 - 0.13 12.7 0.2 0.41 11.2 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1624 PF07786.12 KFR08541.1 - 2.2e-07 30.7 0.9 2.2e-07 30.7 0.9 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1624) DUF5009 PF16401.5 KFR08541.1 - 3.6e-06 26.7 4.8 5.3e-06 26.1 0.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF5009) DUF5531 PF17671.1 KFR08541.1 - 0.16 11.9 2.9 7.4 6.4 0.8 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5531) Pkinase_Tyr PF07714.17 KFR08542.1 - 2.2e-09 37.0 0.1 3.4e-08 33.1 0.2 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KFR08542.1 - 1.7e-05 24.4 0.0 0.00031 20.2 0.1 2.1 2 0 0 2 2 2 1 Protein kinase domain PIP49_C PF12260.8 KFR08542.1 - 0.0022 17.6 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 PIP49_N PF14875.6 KFR08542.1 - 0.083 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 N-term cysteine-rich ER, FAM69 PHO4 PF01384.20 KFR08543.1 - 2.6e-139 464.0 8.7 3.4e-139 463.6 8.7 1.1 1 0 0 1 1 1 1 Phosphate transporter family Vpu PF00558.19 KFR08543.1 - 0.028 14.2 0.2 0.028 14.2 0.2 2.2 2 0 0 2 2 2 0 Vpu protein DUF4605 PF15378.6 KFR08544.1 - 1.9e-25 88.4 6.3 1.9e-25 88.4 6.3 1.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4605) OAR PF03826.17 KFR08545.1 - 4.4e-09 35.9 1.2 1e-08 34.7 1.2 1.7 1 0 0 1 1 1 1 OAR domain Homeodomain PF00046.29 KFR08545.1 - 0.084 12.7 7.7 0.14 12.0 7.7 1.4 1 0 0 1 1 1 0 Homeodomain Peptidase_M1 PF01433.20 KFR08546.1 - 4e-89 297.9 1.0 7e-89 297.1 1.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KFR08546.1 - 6.1e-79 265.8 3.8 7.8e-79 265.5 2.6 1.8 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KFR08546.1 - 5.2e-55 186.5 0.3 1.6e-54 184.9 0.3 1.8 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF1570 PF07607.11 KFR08546.1 - 0.035 14.4 0.1 0.11 12.8 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1570) ELO PF01151.18 KFR08547.1 - 6.9e-68 228.9 22.6 7.9e-68 228.7 22.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Ldl_recept_b PF00058.17 KFR08548.1 - 2.5e-47 159.1 11.5 5.1e-10 39.7 0.0 8.7 10 0 0 10 10 10 6 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 KFR08548.1 - 2.4e-32 110.9 151.2 1.7e-08 34.6 6.5 11.6 11 0 0 11 11 11 7 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFR08548.1 - 1.6e-31 107.9 77.6 1.7e-05 24.7 4.2 11.4 11 0 0 11 11 11 9 Complement Clr-like EGF-like EGF_CA PF07645.15 KFR08548.1 - 1.2e-19 70.2 53.7 1.7e-07 31.4 10.1 11.4 11 0 0 11 11 11 5 Calcium-binding EGF domain EGF PF00008.27 KFR08548.1 - 2.2e-18 66.2 123.2 8.2e-05 22.8 4.7 11.3 11 0 0 11 11 11 8 EGF-like domain DUF5050 PF16472.5 KFR08548.1 - 3.4e-11 42.9 0.0 2.4e-05 23.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF5050) EGF_3 PF12947.7 KFR08548.1 - 5e-11 42.6 132.8 5.7e-06 26.4 12.0 11.0 10 0 0 10 10 10 6 EGF domain SGL PF08450.12 KFR08548.1 - 1.3e-09 38.1 0.2 0.016 14.8 0.0 4.8 2 1 2 4 4 4 3 SMP-30/Gluconolactonase/LRE-like region hEGF PF12661.7 KFR08548.1 - 0.026 15.1 98.0 0.026 15.2 6.8 10.7 9 0 0 9 9 9 0 Human growth factor-like EGF LRR_8 PF13855.6 KFR08549.1 - 3.5e-25 87.5 10.6 1.5e-10 40.7 0.5 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFR08549.1 - 5.3e-15 55.3 5.2 4.1e-10 39.8 1.0 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) Ig_3 PF13927.6 KFR08549.1 - 2.5e-14 53.6 0.4 6.4e-14 52.3 0.4 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFR08549.1 - 9.2e-11 41.7 0.0 1.9e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFR08549.1 - 1.7e-09 37.9 0.4 7.3e-09 35.9 0.1 2.1 2 0 0 2 2 2 1 Immunoglobulin domain LRR_1 PF00560.33 KFR08549.1 - 3.2e-07 30.0 2.1 0.56 11.0 0.1 4.8 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_5 PF13306.6 KFR08549.1 - 2.4e-06 27.5 0.0 4.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) ig PF00047.25 KFR08549.1 - 2.6e-05 24.3 0.2 7e-05 22.9 0.0 1.9 2 1 0 2 2 2 1 Immunoglobulin domain LRR_9 PF14580.6 KFR08549.1 - 8.2e-05 22.2 0.2 0.02 14.4 0.1 2.2 1 1 1 2 2 2 2 Leucine-rich repeat V-set PF07686.17 KFR08549.1 - 0.00056 20.1 0.1 0.011 15.9 0.1 2.4 1 1 0 1 1 1 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFR08549.1 - 0.015 15.4 0.1 0.025 14.7 0.1 1.3 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain LRRNT PF01462.18 KFR08549.1 - 0.056 13.1 7.3 0.33 10.6 1.3 3.7 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 KFR08549.1 - 0.19 11.8 0.2 0.19 11.8 0.2 3.7 4 0 0 4 4 4 0 Leucine Rich repeat 7tm_1 PF00001.21 KFR08550.1 - 1.7e-43 148.9 15.0 2.2e-43 148.5 15.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR08550.1 - 3.5e-11 43.0 12.8 4.3e-11 42.7 12.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srt PF10321.9 KFR08550.1 - 0.058 12.4 18.7 0.18 10.8 18.7 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt NOT2_3_5 PF04153.18 KFR08550.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family TMEM223 PF14640.6 KFR08550.1 - 0.71 10.0 6.4 0.53 10.4 1.7 2.8 2 1 1 3 3 3 0 Transmembrane protein 223 SafA PF17073.5 KFR08550.1 - 5.5 7.0 6.3 1.4 9.0 0.2 2.8 3 0 0 3 3 3 0 Two-component-system connector protein Gar1 PF04410.14 KFR08551.1 - 1.4e-39 135.3 0.0 1.8e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Trypsin PF00089.26 KFR08552.1 - 3.7e-58 196.9 0.8 6.7e-58 196.1 0.8 1.4 1 0 0 1 1 1 1 Trypsin Ldl_recept_a PF00057.18 KFR08552.1 - 1.4e-15 57.2 27.4 3.7e-09 36.6 6.4 4.1 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A SRCR PF00530.18 KFR08552.1 - 6.8e-11 42.6 6.3 5e-10 39.8 1.7 3.2 3 0 0 3 3 3 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFR08552.1 - 2e-06 28.2 2.8 6.8e-06 26.5 1.0 2.5 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Trypsin_2 PF13365.6 KFR08552.1 - 0.00013 22.9 0.0 0.00028 21.8 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain PLA2G12 PF06951.11 KFR08553.1 - 1.1e-63 214.4 9.9 1.2e-63 214.3 9.9 1.0 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) Phospholip_A2_2 PF05826.12 KFR08553.1 - 0.75 10.1 14.9 1.7 8.9 2.6 2.5 1 1 1 2 2 2 0 Phospholipase A2 Peptidase_C14 PF00656.22 KFR08554.1 - 1.2e-54 185.9 0.0 1.4e-54 185.7 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Sec23_trunk PF04811.15 KFR08555.1 - 1.6e-85 286.6 0.2 3.3e-85 285.5 0.1 1.6 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KFR08555.1 - 1.2e-27 95.7 3.3 4.5e-27 93.9 3.3 2.1 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KFR08555.1 - 3.6e-21 75.7 0.0 9.1e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KFR08555.1 - 1.1e-14 54.2 5.3 2.2e-14 53.2 5.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KFR08555.1 - 1.9e-10 40.5 0.0 4.2e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Sen15 PF09631.10 KFR08555.1 - 0.071 13.4 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Sen15 protein HpaB PF03241.13 KFR08555.1 - 0.21 10.7 0.0 0.43 9.6 0.0 1.4 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal OST3_OST6 PF04756.13 KFR08556.1 - 1.4e-08 34.5 1.2 1.7e-08 34.2 1.2 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Ribosomal_L34e PF01199.18 KFR08557.1 - 6e-43 145.1 7.3 7.6e-43 144.8 7.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e CTNNB1_binding PF08347.11 KFR08558.1 - 5.1e-52 177.0 8.2 5.1e-52 177.0 8.2 2.1 2 0 0 2 2 2 1 N-terminal CTNNB1 binding HMG_box PF00505.19 KFR08558.1 - 5.3e-22 78.0 0.7 5.3e-22 78.0 0.7 2.5 3 1 1 4 4 4 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFR08558.1 - 6.3e-09 36.3 0.8 1.8e-08 34.9 0.8 1.7 1 0 0 1 1 1 1 HMG-box domain 3HCDH_N PF02737.18 KFR08559.1 - 5.7e-53 179.5 3.4 7.5e-53 179.1 3.4 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KFR08559.1 - 1.8e-35 121.4 0.0 4e-35 120.3 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain p450 PF00067.22 KFR08560.1 - 9.3e-107 357.6 0.2 1e-106 357.5 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 PAP2_C PF14360.6 KFR08561.1 - 8.5e-28 96.7 14.3 8.5e-28 96.7 14.3 2.3 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 KFR08561.1 - 2.9e-05 23.9 12.7 2.9e-05 23.9 12.7 2.1 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KFR08561.1 - 0.29 10.8 16.6 0.2 11.3 12.1 2.2 2 1 0 2 2 2 0 PAP2 superfamily APS_kinase PF01583.20 KFR08562.1 - 4.8e-75 250.8 0.0 7.5e-75 250.1 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.17 KFR08562.1 - 8.6e-70 234.5 0.1 1.3e-69 234.0 0.1 1.3 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 KFR08562.1 - 3.9e-50 169.6 0.0 7.1e-50 168.8 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.6 KFR08562.1 - 2.1e-07 31.2 0.0 4.7e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFR08562.1 - 0.00042 20.9 0.0 0.0016 19.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain 6PF2K PF01591.18 KFR08562.1 - 0.03 13.6 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase KTI12 PF08433.10 KFR08562.1 - 0.039 13.4 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Thymidylate_kin PF02223.17 KFR08562.1 - 0.041 13.5 0.0 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase PEPCK_ATP PF01293.20 KFR08562.1 - 0.049 12.3 0.2 0.68 8.5 0.1 2.0 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase AAA_28 PF13521.6 KFR08562.1 - 0.057 13.7 0.1 0.53 10.5 0.0 2.6 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.12 KFR08562.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 KFR08562.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Prokineticin PF06607.11 KFR08564.1 - 0.0023 18.2 7.2 0.0028 17.9 7.2 1.1 1 0 0 1 1 1 1 Prokineticin Dickkopf_N PF04706.12 KFR08564.1 - 0.027 14.9 5.9 0.027 14.9 5.9 2.1 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Toxin_21 PF08091.11 KFR08564.1 - 3 7.9 12.4 0.075 13.0 4.7 2.2 2 1 0 2 2 2 0 Spider insecticidal peptide AIG1 PF04548.16 KFR08565.1 - 8e-26 90.7 0.0 1.1e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 KFR08565.1 - 0.0019 18.3 0.0 0.0039 17.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KFR08565.1 - 0.0035 16.7 0.2 0.0073 15.7 0.1 1.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family Septin PF00735.18 KFR08565.1 - 0.011 15.0 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Septin Rep_2 PF01719.17 KFR08565.1 - 0.07 12.9 0.2 0.11 12.3 0.2 1.1 1 0 0 1 1 1 0 Plasmid replication protein tRNA_bind PF01588.20 KFR08566.1 - 8e-31 106.0 0.8 1.2e-30 105.4 0.1 1.7 2 0 0 2 2 2 1 Putative tRNA binding domain Ribosomal_60s PF00428.19 KFR08566.1 - 0.076 13.6 7.1 0.2 12.3 7.1 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein Suf PF05843.14 KFR08566.1 - 0.14 12.1 2.1 0.17 11.9 2.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SR-25 PF10500.9 KFR08566.1 - 0.63 9.6 13.6 1.1 8.8 13.6 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC53 PF10152.9 KFR08566.1 - 0.64 10.4 5.2 1.1 9.6 5.2 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex SlyX PF04102.12 KFR08566.1 - 2 9.1 5.5 21 5.8 5.5 2.5 1 1 0 1 1 1 0 SlyX YabA PF06156.13 KFR08566.1 - 2.2 9.0 7.7 7.7 7.2 7.7 2.0 1 1 0 1 1 1 0 Initiation control protein YabA TSGP1 PF07771.11 KFR08566.1 - 3.3 7.9 8.9 7.6 6.7 8.9 1.5 1 0 0 1 1 1 0 Tick salivary peptide group 1 RR_TM4-6 PF06459.12 KFR08566.1 - 8.4 6.1 11.2 12 5.7 11.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RabGAP-TBC PF00566.18 KFR08567.1 - 1.3e-42 145.9 0.2 2.1e-42 145.2 0.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 KFR08567.1 - 5.6e-36 124.3 0.0 8.3e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR08567.1 - 1.1e-25 90.4 0.0 1.9e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Rhodanese PF00581.20 KFR08567.1 - 1.2e-13 51.5 0.0 2.5e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Kinase-like PF14531.6 KFR08567.1 - 5.1e-05 22.7 0.0 8.5e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like EGF_CA PF07645.15 KFR08568.1 - 3.6e-24 84.7 62.2 1.8e-10 40.8 3.5 5.7 4 1 1 5 5 5 3 Calcium-binding EGF domain MAM PF00629.23 KFR08568.1 - 2.4e-20 73.1 0.0 5.3e-20 71.9 0.0 1.6 1 1 0 1 1 1 1 MAM domain, meprin/A5/mu cEGF PF12662.7 KFR08568.1 - 8.3e-19 67.2 45.9 1.8e-07 30.9 0.8 5.9 6 0 0 6 6 6 5 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFR08568.1 - 2e-09 37.5 77.1 4.6e-05 23.6 9.3 5.5 5 0 0 5 5 5 4 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 KFR08568.1 - 7.4e-06 26.1 65.9 4.6e-05 23.5 13.2 6.0 4 1 1 5 5 5 3 EGF domain EGF PF00008.27 KFR08568.1 - 8.8e-05 22.7 76.6 0.1 12.9 9.1 6.5 5 1 0 5 5 5 5 EGF-like domain Plasmod_Pvs28 PF06247.11 KFR08568.1 - 0.00035 20.8 7.3 0.00035 20.8 7.3 4.6 4 1 0 4 4 4 3 Pvs28 EGF domain EGF_MSP1_1 PF12946.7 KFR08568.1 - 0.0027 17.7 37.3 0.033 14.3 7.5 4.8 4 0 0 4 4 4 3 MSP1 EGF domain 1 EGF_2 PF07974.13 KFR08568.1 - 0.014 15.7 14.7 0.014 15.7 14.7 6.2 5 1 0 5 5 5 0 EGF-like domain hEGF PF12661.7 KFR08568.1 - 4.2 8.1 61.8 0.19 12.4 5.0 7.7 8 1 0 8 8 8 0 Human growth factor-like EGF Methyltransf_32 PF13679.6 KFR08569.1 - 1.4e-10 41.4 3.6 3.2e-09 37.0 3.6 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFR08569.1 - 9.5e-07 28.7 0.0 1.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.14 KFR08569.1 - 6.2e-06 25.9 1.2 0.11 12.0 1.4 2.8 1 1 1 2 2 2 2 Methyltransferase TRM13 GidB PF02527.15 KFR08569.1 - 0.00013 21.4 0.0 0.00024 20.5 0.0 1.4 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G GST_C_2 PF13410.6 KFR08569.1 - 0.00014 21.8 0.0 0.022 14.8 0.0 2.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Methyltransf_4 PF02390.17 KFR08569.1 - 0.0017 17.9 0.0 0.003 17.0 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KFR08569.1 - 0.0035 16.9 0.0 0.0065 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KFR08569.1 - 0.011 16.5 0.1 0.026 15.2 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KFR08569.1 - 0.03 13.7 0.0 0.065 12.6 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family GST_C_3 PF14497.6 KFR08569.1 - 0.031 14.5 0.0 0.076 13.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Methyltransf_16 PF10294.9 KFR08569.1 - 0.065 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase PHD PF00628.29 KFR08570.1 - 1.3e-09 37.8 9.7 2.1e-09 37.1 9.7 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 KFR08570.1 - 5.7e-05 22.9 2.9 5.7e-05 22.9 2.9 1.9 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 KFR08570.1 - 0.00094 18.8 3.0 0.0028 17.3 3.0 1.8 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 KFR08570.1 - 0.0027 17.2 5.4 0.0061 16.1 5.4 1.6 1 0 0 1 1 1 1 PHD-finger zf-RING_9 PF13901.6 KFR08570.1 - 0.0041 17.1 5.7 0.0079 16.2 5.7 1.4 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon Prok-RING_1 PF14446.6 KFR08570.1 - 0.013 15.4 3.8 0.013 15.4 3.8 1.5 2 0 0 2 2 1 0 Prokaryotic RING finger family 1 PHD_4 PF16866.5 KFR08570.1 - 0.019 15.1 9.8 0.073 13.2 9.8 2.0 1 1 0 1 1 1 0 PHD-finger zf-4CXXC_R1 PF10497.9 KFR08570.1 - 0.14 12.4 4.8 0.28 11.4 4.8 1.5 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 FYVE_2 PF02318.16 KFR08570.1 - 0.17 12.1 5.7 0.35 11.1 5.7 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger zinc_ribbon_15 PF17032.5 KFR08570.1 - 0.28 12.0 3.7 0.6 10.9 3.7 1.6 1 0 0 1 1 1 0 zinc-ribbon family Cytochrom_c3_2 PF14537.6 KFR08570.1 - 0.55 10.7 9.0 8.7 6.9 9.0 2.6 1 1 0 1 1 1 0 Cytochrome c3 Zf_RING PF16744.5 KFR08570.1 - 9.8 6.4 9.7 36 4.6 9.6 2.0 1 1 0 1 1 1 0 KIAA1045 RING finger RhoGEF PF00621.20 KFR08571.1 - 8e-15 55.5 0.2 8e-15 55.5 0.2 2.6 2 1 0 2 2 2 1 RhoGEF domain BAR PF03114.18 KFR08571.1 - 1.3e-12 47.9 3.2 3.6e-12 46.5 3.2 1.8 1 0 0 1 1 1 1 BAR domain SH3_2 PF07653.17 KFR08571.1 - 4.1e-11 42.4 0.0 4.9e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 KFR08571.1 - 1e-09 38.1 0.0 2.2e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFR08571.1 - 2.3e-08 33.5 0.5 6.5e-08 32.1 0.1 2.0 2 0 0 2 2 2 1 SH3 domain tRNA_bind_3 PF17176.4 KFR08571.1 - 0.044 14.1 0.5 0.16 12.2 0.1 2.2 2 0 0 2 2 2 0 tRNA-binding domain SH3_3 PF08239.11 KFR08571.1 - 0.077 13.3 0.4 0.83 10.0 0.1 2.2 2 0 0 2 2 2 0 Bacterial SH3 domain RhoGEF PF00621.20 KFR08572.1 - 4.4e-19 69.4 0.7 5.9e-19 69.0 0.7 1.2 1 0 0 1 1 1 1 RhoGEF domain Tet_JBP PF12851.7 KFR08573.1 - 8.3e-136 452.7 4.5 8.3e-136 452.7 4.5 2.3 2 1 0 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily 7tm_1 PF00001.21 KFR08574.1 - 3.4e-58 197.0 19.5 4.5e-58 196.6 19.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR08574.1 - 3.7e-11 42.9 19.8 4.9e-11 42.5 19.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFR08574.1 - 4e-05 23.5 19.0 0.00019 21.3 19.0 2.0 1 1 0 1 1 1 1 Olfactory receptor zf_C2H2_ZHX PF18387.1 KFR08574.1 - 0.079 12.6 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain PsbX PF06596.11 KFR08574.1 - 4.2 7.5 10.0 0.17 11.9 2.3 2.8 3 0 0 3 3 3 0 Photosystem II reaction centre X protein (PsbX) Radial_spoke PF04712.12 KFR08575.1 - 1.1e-204 680.9 13.2 1.1e-204 680.9 13.2 1.9 1 1 1 2 2 2 1 Radial spokehead-like protein TBPIP PF07106.13 KFR08575.1 - 0.00074 19.4 0.0 0.0022 17.9 0.0 1.7 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain SpoIIIAH PF12685.7 KFR08575.1 - 0.026 14.3 7.2 1.1 9.1 0.1 3.0 3 0 0 3 3 3 0 SpoIIIAH-like protein CPSF100_C PF13299.6 KFR08575.1 - 0.56 10.4 13.4 0.5 10.5 0.8 3.3 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal FYDLN_acid PF09538.10 KFR08575.1 - 2.6 8.8 26.8 8.4 7.1 1.4 3.6 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) adh_short_C2 PF13561.6 KFR08576.1 - 1.2e-57 195.2 0.0 1.3e-57 195.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFR08576.1 - 1.6e-41 141.9 0.1 2.1e-41 141.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFR08576.1 - 3.6e-05 23.8 0.1 5.4e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 KR domain AlaDh_PNT_C PF01262.21 KFR08576.1 - 0.0071 15.7 0.1 0.014 14.7 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF2325 PF10087.9 KFR08576.1 - 0.037 14.2 0.1 0.07 13.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) ADH_zinc_N PF00107.26 KFR08576.1 - 0.039 13.9 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 KFR08576.1 - 0.042 14.1 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KFR08576.1 - 0.066 13.1 0.0 0.072 13.0 0.0 1.4 1 1 0 1 1 1 0 NAD(P)H-binding DUF1776 PF08643.10 KFR08576.1 - 0.093 12.1 0.2 0.18 11.2 0.1 1.5 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) FtsJ PF01728.19 KFR08576.1 - 0.14 12.3 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Na_H_Exchanger PF00999.21 KFR08577.1 - 2.4e-25 89.1 36.5 3.8e-25 88.5 36.5 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family zf-CDGSH PF09360.10 KFR08578.1 - 4.4e-10 39.6 0.2 7.4e-10 38.9 0.2 1.4 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type MitoNEET_N PF10660.9 KFR08578.1 - 3.8e-09 36.4 0.0 5.3e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus UQ_con PF00179.26 KFR08579.1 - 2.3e-47 160.1 0.1 2.6e-47 160.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFR08579.1 - 0.011 16.1 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 KFR08579.1 - 0.021 14.5 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 KFR08579.1 - 0.054 13.3 0.1 0.086 12.7 0.1 1.3 1 1 0 1 1 1 0 UEV domain Ig_mannosidase PF17753.1 KFR08580.1 - 2.5e-21 75.2 0.1 8.1e-21 73.6 0.1 2.0 1 0 0 1 1 1 1 Ig-fold domain Mannosidase_ig PF17786.1 KFR08580.1 - 1.6e-12 47.8 0.0 5e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2_C PF02836.17 KFR08580.1 - 2.5e-08 33.4 0.8 1.2e-07 31.2 0.8 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KFR08580.1 - 2.1e-05 24.5 0.5 5e-05 23.3 0.5 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain VP40 PF07447.12 KFR08580.1 - 0.037 13.2 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Matrix protein VP40 RHD_DNA_bind PF00554.22 KFR08581.1 - 6.8e-71 237.7 0.0 1.6e-70 236.5 0.0 1.6 1 0 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.5 KFR08581.1 - 2.9e-40 136.4 0.0 6.1e-40 135.4 0.0 1.6 1 0 0 1 1 1 1 Rel homology dimerisation domain Ank_2 PF12796.7 KFR08581.1 - 5.6e-25 87.7 9.0 1.6e-11 44.6 0.3 4.4 4 1 0 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFR08581.1 - 2.1e-24 85.5 1.2 2.6e-08 34.3 0.1 5.8 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 KFR08581.1 - 1.9e-20 72.3 14.3 0.00017 21.9 0.0 7.4 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 KFR08581.1 - 2.7e-19 67.2 6.5 0.011 16.2 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KFR08581.1 - 1.2e-18 66.9 6.6 7.8e-07 29.3 0.2 5.5 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Death PF00531.22 KFR08581.1 - 3.1e-13 49.7 0.1 6.2e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 Death domain Zip PF02535.22 KFR08582.1 - 1e-69 235.4 3.3 1.2e-69 235.1 3.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4271 PF14093.6 KFR08582.1 - 0.0021 18.0 3.0 0.0021 18.0 3.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4271) DUF5638 PF18688.1 KFR08583.1 - 0.0025 18.1 0.1 0.0042 17.4 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5638) TIR_3 PF18567.1 KFR08585.1 - 4.8e-46 156.0 0.8 9.6e-46 155.0 0.8 1.5 1 0 0 1 1 1 1 Toll/interleukin-1 receptor domain DBB PF14545.6 KFR08585.1 - 3.9e-39 133.8 0.0 6.2e-39 133.1 0.0 1.3 1 0 0 1 1 1 1 Dof, BCAP, and BANK (DBB) motif, Ank_2 PF12796.7 KFR08585.1 - 0.0027 18.3 0.0 0.0062 17.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFR08585.1 - 0.3 11.6 1.4 0.61 10.6 0.1 2.2 2 0 0 2 2 2 0 Ankyrin repeat Metallophos PF00149.28 KFR08588.1 - 1.8e-38 133.1 0.0 2.9e-38 132.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Sel1 PF08238.12 KFR08589.1 - 8.1e-08 32.7 0.2 8.1e-08 32.7 0.2 2.0 3 0 0 3 3 3 1 Sel1 repeat Histone PF00125.24 KFR08590.1 - 1.8e-19 70.4 0.0 2e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFR08590.1 - 0.003 17.8 0.0 0.0042 17.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone_H2A_C PF16211.5 KFR08590.1 - 0.0056 16.4 0.2 0.014 15.1 0.2 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A DUF1977 PF09320.11 KFR08591.1 - 7.9e-27 93.6 2.3 1.4e-26 92.8 2.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 KFR08591.1 - 8.7e-27 93.0 0.6 8.7e-27 93.0 0.6 1.8 2 0 0 2 2 2 1 DnaJ domain DUF1830 PF08865.11 KFR08592.1 - 0.15 12.1 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) MAPKK1_Int PF08923.10 KFR08593.1 - 9.5e-47 157.7 0.0 1e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting SH2 PF00017.24 KFR08594.1 - 6.7e-20 71.0 0.5 1.2e-19 70.2 0.5 1.4 1 0 0 1 1 1 1 SH2 domain PH PF00169.29 KFR08594.1 - 7.5e-19 68.2 0.7 1.4e-18 67.3 0.7 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFR08594.1 - 0.00035 21.0 1.6 0.0017 18.7 1.6 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain Vitellogenin_N PF01347.22 KFR08595.1 - 3.9e-67 227.1 7.6 4.6e-67 226.8 7.6 1.1 1 0 0 1 1 1 1 Lipoprotein amino terminal region HEAT_2 PF13646.6 KFR08595.1 - 0.017 15.5 0.7 5.1 7.6 0.1 2.7 2 1 0 2 2 2 0 HEAT repeats tRNA_m1G_MT PF01746.21 KFR08596.1 - 2.8e-29 102.2 0.3 4.9e-29 101.4 0.3 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase ASC PF00858.24 KFR08596.1 - 0.013 14.5 1.2 0.016 14.2 1.2 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel TAN PF11640.8 KFR08596.1 - 0.034 14.3 4.1 0.079 13.1 4.1 1.5 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair NARP1 PF12569.8 KFR08596.1 - 0.041 12.8 9.1 0.06 12.2 9.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FAM199X PF15814.5 KFR08596.1 - 6.8 5.6 8.8 11 5.0 8.8 1.2 1 0 0 1 1 1 0 Protein family FAM199X SPATIAL PF15256.6 KFR08597.1 - 8.2e-21 75.3 1.0 9.5e-21 75.0 1.0 1.0 1 0 0 1 1 1 1 SPATIAL RNA_pol_Rpb1_R PF05001.13 KFR08597.1 - 0.32 11.4 3.2 3.6 8.1 1.0 2.6 2 0 0 2 2 2 0 RNA polymerase Rpb1 C-terminal repeat ADH_zinc_N PF00107.26 KFR08598.1 - 3.9e-26 91.6 0.1 7.2e-26 90.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFR08598.1 - 2.7e-25 88.4 3.3 3.9e-25 87.9 1.7 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain IGFBP PF00219.18 KFR08598.1 - 0.0088 16.7 0.2 0.026 15.2 0.2 1.8 1 0 0 1 1 1 1 Insulin-like growth factor binding protein UDPG_MGDP_dh_N PF03721.14 KFR08598.1 - 0.01 15.5 0.2 0.021 14.4 0.2 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 KFR08598.1 - 0.06 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 KFR08598.1 - 0.084 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KFR08599.1 - 6.7e-26 90.8 0.1 1.1e-25 90.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFR08599.1 - 2.7e-25 88.3 1.5 8.2e-25 86.8 1.5 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KFR08599.1 - 0.00013 21.6 0.4 0.00052 19.6 0.2 2.1 1 1 1 2 2 2 1 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 KFR08599.1 - 0.022 14.3 0.1 0.034 13.7 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KFR08599.1 - 0.054 12.8 0.1 0.087 12.2 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KFR08599.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ADH_zinc_N PF00107.26 KFR08600.1 - 8.2e-25 87.3 0.6 1.6e-24 86.3 0.6 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFR08600.1 - 8.3e-25 86.8 1.9 2.1e-24 85.5 1.9 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFR08600.1 - 0.00018 22.5 0.0 0.00029 21.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 KFR08600.1 - 0.031 13.8 0.1 0.053 13.1 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KFR08600.1 - 0.18 11.2 0.1 0.31 10.4 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peptidase_M24 PF00557.24 KFR08601.1 - 1.8e-53 181.3 0.4 2.3e-53 181.0 0.4 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KFR08601.1 - 0.0043 17.3 1.1 0.0043 17.3 1.1 1.8 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding Pyr_redox_dim PF02852.22 KFR08601.1 - 0.021 15.1 0.2 0.038 14.3 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain IF4E PF01652.18 KFR08602.1 - 3e-56 189.6 0.2 3.5e-56 189.4 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Tetraspanin PF00335.20 KFR08603.1 - 3e-62 210.3 9.7 3.5e-62 210.1 9.7 1.0 1 0 0 1 1 1 1 Tetraspanin family Arm PF00514.23 KFR08604.1 - 1.6e-36 123.2 13.4 1.9e-08 34.1 0.1 6.9 6 0 0 6 6 6 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KFR08604.1 - 2.5e-05 24.6 5.1 0.46 10.9 0.0 4.3 2 2 2 4 4 4 2 HEAT repeats KAP PF05804.12 KFR08604.1 - 6.8e-05 21.2 7.7 0.00079 17.7 0.2 2.5 2 1 0 2 2 2 2 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 KFR08604.1 - 0.00049 19.5 7.2 0.1 11.9 1.9 4.1 1 1 1 2 2 2 1 V-ATPase subunit H HEAT_EZ PF13513.6 KFR08604.1 - 0.0034 17.9 10.8 0.41 11.2 0.2 4.6 5 1 0 5 5 5 2 HEAT-like repeat Adaptin_N PF01602.20 KFR08604.1 - 0.004 15.8 8.8 0.47 8.9 0.2 3.3 2 1 1 3 3 3 2 Adaptin N terminal region Atx10homo_assoc PF09759.9 KFR08604.1 - 0.0041 17.1 1.7 0.022 14.8 0.1 2.8 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 KFR08604.1 - 0.0077 16.4 2.4 7.1 7.2 0.1 4.4 3 1 0 3 3 3 1 HEAT repeat SNase PF00565.17 KFR08604.1 - 0.019 15.5 0.1 3.8 8.0 0.1 2.8 2 0 0 2 2 2 0 Staphylococcal nuclease homologue RICTOR_V PF14668.6 KFR08604.1 - 0.025 14.8 2.5 5.7 7.2 0.1 4.3 3 2 2 5 5 5 0 Rapamycin-insensitive companion of mTOR, domain 5 Nitr_red_bet_C PF14711.6 KFR08604.1 - 0.074 12.8 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal RNaseH_C PF09293.10 KFR08604.1 - 0.17 12.3 0.1 0.59 10.5 0.0 1.9 2 0 0 2 2 2 0 T4 RNase H, C terminal Wap1 PF16997.5 KFR08604.1 - 1.7 7.7 7.4 0.24 10.5 1.4 2.4 2 1 0 2 2 2 0 Wap1 domain UPA PF17217.3 KFR08607.1 - 9.1e-72 239.5 0.6 1.7e-71 238.6 0.6 1.4 1 0 0 1 1 1 1 UPA domain ZU5 PF00791.20 KFR08607.1 - 2.6e-34 117.5 0.1 7e-34 116.1 0.1 1.7 1 0 0 1 1 1 1 ZU5 domain Death PF00531.22 KFR08607.1 - 1.3e-14 54.1 0.2 3.7e-14 52.6 0.0 1.9 2 0 0 2 2 2 1 Death domain Ig_3 PF13927.6 KFR08607.1 - 1.3e-13 51.3 0.3 3.7e-09 37.0 0.0 3.6 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFR08607.1 - 2.5e-12 46.7 2.1 6.3e-11 42.2 0.1 3.2 3 0 0 3 3 3 1 Immunoglobulin I-set domain TSP_1 PF00090.19 KFR08607.1 - 3e-10 40.2 29.7 4e-08 33.3 8.8 2.8 2 0 0 2 2 2 2 Thrombospondin type 1 domain Ig_2 PF13895.6 KFR08607.1 - 4.6e-08 33.3 0.1 7.3e-06 26.2 0.0 3.6 3 0 0 3 3 3 1 Immunoglobulin domain ig PF00047.25 KFR08607.1 - 8.8e-07 29.0 0.0 3.6e-05 23.9 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin domain V-set PF07686.17 KFR08607.1 - 0.01 16.0 0.4 1.8 8.8 0.1 3.3 2 1 0 2 2 2 0 Immunoglobulin V-set domain AtuA PF07287.11 KFR08607.1 - 0.031 13.0 0.0 0.053 12.2 0.0 1.2 1 0 0 1 1 1 0 Acyclic terpene utilisation family protein AtuA Pkinase_Tyr PF07714.17 KFR08608.1 - 9.6e-38 129.9 0.0 1.3e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR08608.1 - 3.9e-36 124.8 0.0 6.3e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.12 KFR08608.1 - 4.3e-16 58.1 0.5 9.1e-16 57.1 0.5 1.6 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.23 KFR08608.1 - 6.5e-10 40.0 2.1 7.5e-10 39.8 0.8 1.9 2 0 0 2 2 2 1 Activin types I and II receptor domain FTA2 PF13095.6 KFR08608.1 - 0.008 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 LRRC37AB_C PF14914.6 KFR08608.1 - 0.068 13.1 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Haspin_kinase PF12330.8 KFR08608.1 - 0.079 11.9 0.1 0.13 11.1 0.1 1.4 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KFR08608.1 - 0.2 11.5 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFR08608.1 - 0.28 10.7 0.7 26 4.3 0.1 2.5 2 1 1 3 3 3 0 Choline/ethanolamine kinase LIM PF00412.22 KFR08609.1 - 1.1e-39 134.5 28.2 6.1e-14 52.0 4.3 3.3 3 0 0 3 3 3 3 LIM domain PDZ PF00595.24 KFR08609.1 - 1.6e-12 47.6 0.0 3.1e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain DUF4749 PF15936.5 KFR08609.1 - 1.1e-08 36.1 0.2 2.4e-08 35.0 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4749) PDZ_6 PF17820.1 KFR08609.1 - 0.00011 22.0 0.1 0.00024 20.9 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFR08609.1 - 0.087 13.2 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 PDZ domain 7tm_1 PF00001.21 KFR08610.1 - 1.6e-54 185.0 17.4 1.9e-54 184.7 17.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR08610.1 - 4.5e-16 59.0 14.1 5.7e-16 58.7 14.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFR08610.1 - 3.9e-14 52.9 17.2 6.1e-14 52.3 17.2 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFR08610.1 - 3.5e-10 39.7 6.8 6.1e-10 38.9 6.8 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFR08610.1 - 8.5e-07 29.0 5.1 8.5e-07 29.0 5.1 2.5 2 1 0 2 2 2 1 Olfactory receptor Git3 PF11710.8 KFR08610.1 - 0.0051 16.6 11.9 0.0051 16.6 11.9 1.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 CcmH PF03918.14 KFR08610.1 - 0.093 12.0 0.1 0.25 10.6 0.0 1.7 2 0 0 2 2 2 0 Cytochrome C biogenesis protein SNARE PF05739.19 KFR08610.1 - 0.66 10.0 3.4 12 6.0 0.4 2.7 2 0 0 2 2 2 0 SNARE domain DUF4282 PF14110.6 KFR08610.1 - 0.73 10.6 9.4 0.17 12.6 0.6 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4282) Baculo_11_kDa PF06143.11 KFR08610.1 - 6.2 6.5 6.7 1.1 8.9 0.3 2.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family GST_C_3 PF14497.6 KFR08611.1 - 2.2e-17 63.1 0.0 3.7e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFR08611.1 - 4.3e-12 46.2 0.0 9.5e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFR08611.1 - 1.2e-05 25.5 0.0 1.8e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFR08611.1 - 0.00068 20.0 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KFR08611.1 - 0.0021 18.8 0.0 0.0036 18.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N_2 PF13409.6 KFR08611.1 - 0.0044 17.3 0.0 0.0084 16.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KFR08611.1 - 0.049 13.4 0.0 0.15 11.9 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SNF2_N PF00176.23 KFR08612.1 - 9.4e-59 198.9 1.7 1.5e-58 198.2 1.7 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFR08612.1 - 3.9e-18 65.8 0.0 2.2e-17 63.4 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFR08612.1 - 4.8e-09 36.5 0.0 2.1e-08 34.3 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CUE PF02845.16 KFR08612.1 - 1.7e-07 30.8 0.3 0.013 15.2 0.0 2.6 2 0 0 2 2 2 2 CUE domain ERCC3_RAD25_C PF16203.5 KFR08612.1 - 4.7e-07 29.3 0.1 1.6e-06 27.6 0.1 1.9 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 KFR08612.1 - 4.4e-05 23.3 0.0 0.00018 21.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase HHH_3 PF12836.7 KFR08612.1 - 0.01 16.1 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Pre-PUA PF17832.1 KFR08612.1 - 0.11 13.2 2.8 30 5.4 0.0 3.9 4 0 0 4 4 4 0 Pre-PUA-like domain Lig_chan PF00060.26 KFR08613.1 - 2.2e-41 141.1 0.6 3.6e-41 140.5 0.6 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.28 KFR08613.1 - 2.4e-39 135.5 0.1 6.7e-39 134.0 0.0 1.7 2 0 0 2 2 2 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.9 KFR08613.1 - 1.1e-35 122.3 0.0 2e-35 121.4 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFR08613.1 - 2.5e-21 76.2 0.0 4.8e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Desmo_N PF06771.11 KFR08613.1 - 0.01 16.2 0.1 0.026 14.9 0.1 1.7 1 0 0 1 1 1 0 Viral Desmoplakin N-terminus P5-ATPase PF12409.8 KFR08613.1 - 1.2 9.3 3.2 20 5.3 1.5 2.6 2 0 0 2 2 2 0 P5-type ATPase cation transporter ANF_receptor PF01094.28 KFR08615.1 - 0.0039 16.4 0.0 0.0039 16.3 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region TMF_DNA_bd PF12329.8 KFR08617.1 - 0.0056 16.6 0.4 0.01 15.8 0.2 1.6 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding C1q PF00386.21 KFR08619.1 - 2e-25 89.5 0.3 3e-24 85.6 0.0 3.1 2 0 0 2 2 2 1 C1q domain EMI PF07546.13 KFR08619.1 - 2.5e-13 50.5 3.6 2.5e-13 50.5 3.6 2.2 2 0 0 2 2 2 1 EMI domain EGF PF00008.27 KFR08619.1 - 9.2e-06 25.9 7.2 9.2e-06 25.9 7.2 1.7 2 0 0 2 2 2 1 EGF-like domain hEGF PF12661.7 KFR08619.1 - 0.015 15.9 5.7 0.038 14.6 5.7 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF Topo-VIb_trans PF09239.11 KFR08619.1 - 0.029 14.2 1.0 0.12 12.2 0.1 2.5 2 0 0 2 2 2 0 Topoisomerase VI B subunit, transducer BclA_C PF18573.1 KFR08619.1 - 0.046 13.6 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 BclA C-terminal domain DUF2521 PF10730.9 KFR08619.1 - 0.1 12.6 2.1 0.4 10.7 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2521) EGF_CA PF07645.15 KFR08619.1 - 0.13 12.5 6.1 0.48 10.7 6.1 1.9 1 0 0 1 1 1 0 Calcium-binding EGF domain DUF4023 PF13215.6 KFR08619.1 - 1.6 8.8 4.8 2 8.5 1.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) YvrJ PF12841.7 KFR08619.1 - 2.2 7.9 4.6 9.4 5.9 0.1 4.0 4 0 0 4 4 4 0 YvrJ protein family Synuclein PF01387.17 KFR08621.1 - 1.2e-55 187.4 17.3 1.4e-55 187.1 17.3 1.0 1 0 0 1 1 1 1 Synuclein RhoGAP PF00620.27 KFR08622.1 - 1.1e-44 151.9 0.6 5.9e-44 149.6 0.0 2.4 2 0 0 2 2 2 1 RhoGAP domain DUF4314 PF14192.6 KFR08622.1 - 0.13 12.2 0.6 0.42 10.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4314) HBM PF16591.5 KFR08622.1 - 2.9 7.3 10.1 0.46 9.9 0.4 3.2 3 0 0 3 3 3 0 Helical bimodular sensor domain Dsh_C PF12316.8 KFR08622.1 - 4.3 7.7 9.5 13 6.2 9.5 1.7 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal RCC1 PF00415.18 KFR08624.1 - 8e-86 282.5 30.6 4.6e-14 52.8 0.1 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.25 KFR08624.1 - 8.4e-82 275.1 0.3 1.2e-81 274.6 0.3 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1_2 PF13540.6 KFR08624.1 - 3.2e-48 160.6 41.9 7.4e-10 38.4 0.1 7.7 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat Peptidase_C25_C PF03785.14 KFR08624.1 - 0.08 12.8 0.0 0.82 9.5 0.0 2.6 1 1 1 2 2 2 0 Peptidase family C25, C terminal ig-like domain HECT PF00632.25 KFR08625.1 - 4.9e-33 114.9 0.0 5.4e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Trm112p PF03966.16 KFR08626.1 - 0.0012 19.4 0.0 0.0016 19.0 0.0 1.2 1 0 0 1 1 1 1 Trm112p-like protein CwsA PF10814.8 KFR08626.1 - 0.043 14.0 0.0 0.05 13.8 0.0 1.0 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA YaaC PF14175.6 KFR08626.1 - 0.22 10.8 0.0 0.22 10.7 0.0 1.0 1 0 0 1 1 1 0 YaaC-like Protein RCC1 PF00415.18 KFR08627.1 - 4e-47 158.6 14.3 3.5e-14 53.1 0.1 4.2 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFR08627.1 - 3.1e-18 65.1 28.9 2.7e-08 33.4 1.3 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat X PF00739.19 KFR08627.1 - 0.057 13.5 0.1 2.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Trans-activation protein X RNA_pol_Rpb2_6 PF00562.28 KFR08628.1 - 2.5e-128 428.5 0.2 3.6e-128 427.9 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KFR08628.1 - 3e-68 229.3 0.1 6.6e-68 228.2 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KFR08628.1 - 3e-56 190.1 0.0 8.9e-56 188.5 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KFR08628.1 - 4e-34 116.9 1.5 7.6e-34 116.0 0.2 2.2 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 KFR08628.1 - 3e-24 85.1 0.8 7.6e-24 83.8 0.8 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KFR08628.1 - 6.4e-24 83.9 0.0 1.6e-23 82.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KFR08628.1 - 7.8e-19 68.0 0.5 1.9e-18 66.7 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Amidoligase_2 PF12224.8 KFR08628.1 - 0.022 14.5 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme zf-H2C2_2 PF13465.6 KFR08629.1 - 2.8e-29 100.2 67.4 3.4e-08 33.5 1.3 11.4 11 1 0 11 11 11 7 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFR08629.1 - 7.9e-28 95.9 64.1 1.3e-06 28.0 4.3 8.7 9 0 0 9 9 9 6 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFR08629.1 - 3.7e-18 64.9 78.7 0.00037 20.8 4.0 9.5 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR08629.1 - 5e-12 45.6 72.4 0.049 14.5 0.8 9.7 9 0 0 9 9 9 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFR08629.1 - 0.013 15.8 0.9 0.013 15.8 0.9 7.5 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFR08629.1 - 1 9.8 43.0 0.61 10.4 7.7 6.1 2 1 5 7 7 7 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 KFR08629.1 - 2.1 8.2 11.6 8.1 6.3 0.1 5.5 3 1 1 5 5 5 0 GAGA factor SARAF PF06682.12 KFR08630.1 - 5.3e-83 279.4 1.1 5.9e-83 279.3 1.1 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Vps55 PF04133.14 KFR08631.1 - 7.1e-40 135.6 6.1 8e-40 135.5 6.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF4231 PF14015.6 KFR08631.1 - 0.067 13.7 0.4 0.11 12.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) YwiC PF14256.6 KFR08631.1 - 0.089 13.1 6.4 0.2 12.0 6.4 1.6 1 1 0 1 1 1 0 YwiC-like protein SRP72 PF08492.12 KFR08632.1 - 2.6e-22 79.0 10.3 2.6e-22 79.0 10.3 3.0 2 0 0 2 2 2 1 SRP72 RNA-binding domain SRP_TPR_like PF17004.5 KFR08632.1 - 1.2e-20 73.7 3.5 1.2e-20 73.7 3.5 3.1 2 1 0 3 3 3 1 Putative TPR-like repeat TPR_19 PF14559.6 KFR08632.1 - 5e-14 52.6 12.0 0.0018 18.7 0.1 7.0 4 3 2 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFR08632.1 - 5.1e-13 48.1 21.1 0.0063 16.5 0.0 8.1 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFR08632.1 - 4.2e-12 45.8 4.3 0.38 11.7 0.0 7.0 6 2 1 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFR08632.1 - 1.6e-10 40.3 10.5 0.026 14.3 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFR08632.1 - 1.9e-09 37.6 21.6 8.7e-05 22.7 2.5 6.2 4 3 3 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KFR08632.1 - 6.8e-08 32.1 12.7 0.14 12.4 0.9 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFR08632.1 - 1.2e-07 31.9 22.2 0.00024 21.3 0.9 7.0 7 3 1 8 8 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFR08632.1 - 1.7e-05 25.1 20.0 0.51 11.1 0.1 7.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFR08632.1 - 2.3e-05 24.0 10.8 0.18 11.5 0.0 5.5 6 0 0 6 6 5 2 TPR repeat HrpB1_HrpK PF09613.10 KFR08632.1 - 0.00014 21.5 5.0 0.0038 16.9 0.6 4.4 4 2 0 5 5 5 1 Bacterial type III secretion protein (HrpB1_HrpK) PPR PF01535.20 KFR08632.1 - 0.00021 21.3 0.1 25 5.4 0.0 5.5 6 0 0 6 6 5 0 PPR repeat TPR_16 PF13432.6 KFR08632.1 - 0.00073 20.1 3.9 14 6.5 0.4 6.1 6 1 2 8 8 7 0 Tetratricopeptide repeat BTAD PF03704.17 KFR08632.1 - 0.001 19.5 8.4 0.054 13.9 0.3 4.8 4 2 0 4 4 4 1 Bacterial transcriptional activator domain TPR_9 PF13371.6 KFR08632.1 - 0.0018 18.4 1.7 22 5.3 0.0 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFR08632.1 - 0.0039 17.1 9.0 32 4.9 0.0 6.1 7 0 0 7 7 5 0 Tetratricopeptide repeat CorA PF01544.18 KFR08632.1 - 0.018 14.4 0.4 0.049 12.9 0.4 1.7 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein PMEI PF04043.15 KFR08632.1 - 0.029 14.7 8.9 0.13 12.6 0.5 3.8 3 1 0 3 3 3 0 Plant invertase/pectin methylesterase inhibitor HemY_N PF07219.13 KFR08632.1 - 0.029 14.5 1.9 28 5.0 0.0 4.1 3 0 0 3 3 3 0 HemY protein N-terminus ATP13 PF12921.7 KFR08632.1 - 0.047 13.5 0.1 4.3 7.2 0.0 3.3 2 1 1 3 3 3 0 Mitochondrial ATPase expression PPR_2 PF13041.6 KFR08632.1 - 0.049 13.8 0.3 87 3.4 0.0 4.6 5 0 0 5 5 4 0 PPR repeat family TPR_17 PF13431.6 KFR08632.1 - 0.23 12.0 3.9 41 4.9 0.0 5.2 6 0 0 6 6 4 0 Tetratricopeptide repeat DUF4298 PF14131.6 KFR08632.1 - 0.54 10.3 5.5 2.5 8.1 0.6 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) TPR_10 PF13374.6 KFR08632.1 - 0.89 9.5 5.9 36 4.4 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 KFR08632.1 - 5.3 7.1 5.4 28 4.8 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat CCDC-167 PF15188.6 KFR08632.1 - 5.8 7.3 6.9 0.64 10.4 0.5 2.6 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Arf PF00025.21 KFR08633.1 - 4.7e-38 130.4 0.0 5.3e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFR08633.1 - 2e-12 46.9 0.0 2.4e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KFR08633.1 - 2.1e-10 40.9 0.0 3.5e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFR08633.1 - 2.1e-09 37.2 0.0 2.4e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KFR08633.1 - 1e-05 25.0 0.0 1.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KFR08633.1 - 0.0006 19.1 0.1 0.032 13.4 0.0 2.2 1 1 1 2 2 2 1 G-protein alpha subunit AAA_22 PF13401.6 KFR08633.1 - 0.00097 19.4 0.2 0.0068 16.7 0.2 2.1 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KFR08633.1 - 0.0012 18.9 0.0 0.0018 18.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFR08633.1 - 0.0031 17.9 0.1 0.0058 17.0 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KFR08633.1 - 0.015 15.7 0.1 0.067 13.6 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KFR08633.1 - 0.045 14.3 0.1 0.064 13.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KFR08633.1 - 0.051 13.4 0.2 2.5 7.8 0.1 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SRP54 PF00448.22 KFR08633.1 - 0.066 12.8 0.1 0.14 11.8 0.0 1.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain cobW PF02492.19 KFR08633.1 - 0.084 12.5 0.1 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NOG1 PF06858.14 KFR08633.1 - 0.087 12.6 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) NACHT PF05729.12 KFR08633.1 - 0.15 12.0 0.6 1.8 8.5 0.6 2.1 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KFR08633.1 - 0.15 12.6 0.1 0.34 11.4 0.1 1.8 1 1 0 1 1 1 0 ABC transporter Homeodomain PF00046.29 KFR08634.1 - 1.3e-09 37.7 0.1 1.5e-09 37.5 0.1 1.1 1 0 0 1 1 1 1 Homeodomain Colicin_Pyocin PF01320.18 KFR08634.1 - 0.017 15.2 0.0 0.023 14.8 0.0 1.2 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein GlgS PF08971.11 KFR08634.1 - 0.13 12.4 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycogen synthesis protein Homez PF11569.8 KFR08634.1 - 0.13 11.7 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Kazal_1 PF00050.21 KFR08635.1 - 8e-14 51.4 5.8 8.5e-14 51.3 5.8 1.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KFR08635.1 - 2e-09 37.4 2.8 2.4e-09 37.2 2.8 1.1 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain DSPc PF00782.20 KFR08636.1 - 1.4e-44 151.1 0.1 1.8e-44 150.8 0.1 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFR08636.1 - 4e-06 26.6 0.0 5.1e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KFR08636.1 - 0.031 14.0 0.1 0.046 13.4 0.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 KFR08636.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF1610 PF07754.11 KFR08636.1 - 4.9 7.2 7.7 0.52 10.3 0.2 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF1610) Ank_5 PF13857.6 KFR08637.1 - 7.2e-112 364.0 40.0 4.4e-13 49.2 0.3 14.8 5 5 10 15 15 15 14 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFR08637.1 - 8.4e-111 362.8 52.6 7.9e-15 55.2 0.3 11.3 4 4 7 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFR08637.1 - 2.5e-109 356.4 46.3 3.4e-13 49.8 0.2 14.8 7 5 9 17 17 17 16 Ankyrin repeats (many copies) Ank PF00023.30 KFR08637.1 - 1.5e-108 350.9 50.4 9.2e-08 32.2 0.1 18.6 18 0 0 18 18 18 15 Ankyrin repeat Ank_3 PF13606.6 KFR08637.1 - 2.4e-94 297.8 30.9 8.1e-07 28.9 0.1 19.0 20 0 0 20 20 20 16 Ankyrin repeat PARP PF00644.20 KFR08637.1 - 7.2e-27 94.3 4.8 1.7e-24 86.5 4.8 2.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SAM_2 PF07647.17 KFR08637.1 - 8.7e-15 54.6 0.4 1.9e-14 53.5 0.4 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFR08637.1 - 3.2e-12 46.7 0.6 7.2e-12 45.6 0.6 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Vps39_1 PF10366.9 KFR08637.1 - 0.019 15.2 1.8 16 5.9 0.1 4.3 4 1 1 5 5 5 0 Vacuolar sorting protein 39 domain 1 LRR_8 PF13855.6 KFR08638.1 - 3.2e-20 71.7 12.0 1.8e-11 43.6 3.8 3.9 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KFR08638.1 - 3.8e-19 68.4 9.2 1.2e-06 28.8 2.0 4.9 1 1 0 4 4 4 4 Leucine Rich repeats (2 copies) COR PF16095.5 KFR08638.1 - 2.9e-13 50.1 0.0 1.1e-12 48.1 0.0 1.9 1 1 0 1 1 1 1 C-terminal of Roc, COR, domain LRR_9 PF14580.6 KFR08638.1 - 4.5e-07 29.5 1.9 0.039 13.5 0.5 3.3 1 1 2 3 3 3 3 Leucine-rich repeat Roc PF08477.13 KFR08638.1 - 0.0001 22.5 0.0 0.0067 16.6 0.0 2.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase LRR_1 PF00560.33 KFR08638.1 - 0.00032 20.8 13.3 1.9 9.3 0.6 7.3 7 0 0 7 7 7 1 Leucine Rich Repeat RsmF_methylt_CI PF17126.5 KFR08638.1 - 0.00032 20.7 0.6 16 5.6 0.0 4.6 3 1 1 4 4 4 1 RsmF rRNA methyltransferase first C-terminal domain LRR_6 PF13516.6 KFR08638.1 - 0.094 12.8 2.6 41 4.6 0.0 4.1 3 0 0 3 3 3 0 Leucine Rich repeat RNase_T PF00929.24 KFR08639.1 - 8.2e-30 104.5 0.0 1.8e-29 103.4 0.0 1.5 2 0 0 2 2 2 1 Exonuclease SAP PF02037.27 KFR08639.1 - 6.1e-08 32.2 0.7 1.2e-07 31.3 0.7 1.5 1 0 0 1 1 1 1 SAP domain CBM_21 PF03370.13 KFR08640.1 - 2.4e-32 111.4 0.3 4.4e-32 110.6 0.3 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KFR08640.1 - 6.3e-13 49.1 0.3 1.3e-12 48.1 0.3 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Ldl_recept_a PF00057.18 KFR08641.1 - 4.7e-41 138.7 107.4 1.6e-09 37.8 9.7 7.2 8 0 0 8 8 8 6 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 KFR08641.1 - 1.5e-20 73.4 3.8 2e-09 37.8 0.0 5.7 5 0 0 5 5 5 4 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 KFR08641.1 - 1.8e-10 40.9 23.0 5e-08 33.1 6.6 7.9 6 1 2 8 8 8 3 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFR08641.1 - 1.6e-09 37.5 7.1 3.9e-06 26.7 0.3 4.9 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF_CA PF07645.15 KFR08641.1 - 9.2e-08 32.2 3.9 9.2e-08 32.2 3.9 7.8 6 1 2 8 8 8 1 Calcium-binding EGF domain PMP22_Claudin PF00822.20 KFR08642.1 - 1.8e-16 60.5 0.0 2.3e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Clc-like PF07062.12 KFR08642.1 - 0.00075 19.0 0.4 0.0017 17.8 0.0 1.7 2 0 0 2 2 2 1 Clc-like L_HMGIC_fpl PF10242.9 KFR08642.1 - 0.0046 17.2 0.9 0.0067 16.7 0.9 1.4 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 KFR08642.1 - 0.015 15.1 9.5 0.039 13.7 6.5 2.7 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF1282 PF06930.12 KFR08642.1 - 0.027 14.2 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) DUF4383 PF14325.6 KFR08642.1 - 0.038 14.3 3.9 3 8.1 2.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4383) DUF202 PF02656.15 KFR08642.1 - 0.072 13.5 5.6 2.1 8.9 3.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF4064 PF13273.6 KFR08642.1 - 0.15 12.4 1.2 0.56 10.5 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) SUR7 PF06687.12 KFR08642.1 - 0.15 11.7 1.1 1.1 8.9 0.1 2.3 1 1 1 2 2 2 0 SUR7/PalI family DUF1418 PF07214.12 KFR08642.1 - 0.56 10.1 3.8 1 9.3 0.4 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1418) DUF4131 PF13567.6 KFR08642.1 - 5.4 6.6 8.6 1.2 8.7 5.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Caskin-Pro-rich PF16907.5 KFR08643.1 - 0.032 14.7 0.3 0.032 14.7 0.3 2.9 3 0 0 3 3 3 0 Proline rich region of Caskin proteins MBOAT PF03062.19 KFR08644.1 - 2.3e-14 53.5 7.8 2.3e-11 43.7 5.7 2.3 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family RnaseA PF00074.20 KFR08645.1 - 0.00054 20.4 0.0 0.00061 20.2 0.0 1.1 1 0 0 1 1 1 1 Pancreatic ribonuclease DUF5505 PF17610.2 KFR08645.1 - 0.066 13.2 0.0 0.067 13.2 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5505) Ribosomal_S3Ae PF01015.18 KFR08646.1 - 1.5e-99 331.6 7.0 1.8e-99 331.4 7.0 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 KFR08646.1 - 0.0048 16.5 0.2 0.026 14.1 0.1 2.2 1 1 1 2 2 2 1 Partial alpha/beta-hydrolase lipase region NLRC4_HD2 PF17776.1 KFR08646.1 - 0.01 16.4 0.2 0.014 15.9 0.2 1.2 1 0 0 1 1 1 0 NLRC4 helical domain HD2 GatB_N PF02934.15 KFR08647.1 - 9.5e-83 277.7 0.1 1.3e-82 277.3 0.1 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KFR08647.1 - 5.1e-40 136.8 7.2 8.6e-40 136.0 7.2 1.4 1 0 0 1 1 1 1 GatB domain EMP24_GP25L PF01105.24 KFR08647.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD WD40 PF00400.32 KFR08650.1 - 1.2e-43 146.2 36.0 2.6e-07 31.2 0.1 8.2 7 1 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 KFR08650.1 - 4e-13 49.0 1.7 6.9e-13 48.3 1.7 1.4 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KFR08650.1 - 7.3e-13 48.6 6.4 0.35 11.2 0.1 6.4 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFR08650.1 - 1.1e-11 44.1 19.1 0.027 13.1 0.1 7.0 5 3 3 8 8 8 5 Nucleoporin Nup120/160 F-box PF00646.33 KFR08650.1 - 1.3e-08 34.5 0.3 2.2e-08 33.8 0.3 1.4 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.6 KFR08650.1 - 0.00012 21.7 3.2 0.0022 17.6 1.5 3.5 2 1 0 2 2 2 1 PQQ-like domain Ge1_WD40 PF16529.5 KFR08650.1 - 0.001 18.1 11.1 1 8.3 0.2 5.3 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KFR08650.1 - 0.037 13.0 8.7 0.5 9.2 0.1 4.9 2 2 3 6 6 6 0 Partner and localizer of BRCA2 WD40 domain CDtoxinA PF03498.14 KFR08650.1 - 0.051 13.2 3.4 3.7 7.1 0.5 3.5 1 1 3 4 4 4 0 Cytolethal distending toxin A/C domain PQQ PF01011.21 KFR08650.1 - 0.087 12.8 0.0 1.6e+02 2.5 0.0 4.9 5 0 0 5 5 5 0 PQQ enzyme repeat Nop14 PF04147.12 KFR08650.1 - 0.12 10.6 19.4 0.15 10.2 19.4 1.1 1 0 0 1 1 1 0 Nop14-like family Hira PF07569.11 KFR08650.1 - 0.21 11.3 6.4 13 5.4 0.0 4.5 4 2 2 6 6 6 0 TUP1-like enhancer of split Cwf_Cwc_15 PF04889.12 KFR08650.1 - 2.5 7.8 21.4 4.3 7.0 21.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TMEM154 PF15102.6 KFR08651.1 - 2.2e-37 128.1 2.2 2.5e-37 127.9 2.2 1.1 1 0 0 1 1 1 1 TMEM154 protein family Orf78 PF06024.12 KFR08651.1 - 0.00022 21.5 0.1 0.00038 20.7 0.1 1.4 1 0 0 1 1 1 1 Orf78 (ac78) RIFIN PF02009.16 KFR08651.1 - 0.0092 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Rifin DUF3377 PF11857.8 KFR08651.1 - 0.017 15.1 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) FliP PF00813.20 KFR08651.1 - 0.026 14.4 0.1 0.035 14.0 0.1 1.2 1 0 0 1 1 1 0 FliP family Ac76 PF05814.11 KFR08651.1 - 0.032 14.2 0.1 0.06 13.4 0.1 1.5 1 0 0 1 1 1 0 Orf76 (Ac76) CcmH PF03918.14 KFR08651.1 - 0.038 13.3 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein LAX PF15681.5 KFR08651.1 - 0.047 12.5 1.1 0.071 11.9 0.5 1.5 1 1 0 1 1 1 0 Lymphocyte activation family X DUF2207 PF09972.9 KFR08651.1 - 0.062 12.1 0.0 0.064 12.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4448 PF14610.6 KFR08651.1 - 0.078 12.7 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) EphA2_TM PF14575.6 KFR08651.1 - 0.12 13.3 0.0 0.16 12.9 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CcmD PF04995.14 KFR08651.1 - 0.15 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DDE_1 PF03184.19 KFR08652.1 - 2.6e-34 118.4 0.1 4.4e-34 117.6 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFR08652.1 - 9.5e-21 73.6 0.0 1.7e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFR08652.1 - 1.2e-08 34.4 2.2 2.2e-08 33.6 2.2 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain CENP-B_dimeris PF09026.10 KFR08652.1 - 0.0011 19.3 1.5 0.0025 18.1 1.5 1.6 1 0 0 1 1 1 1 Centromere protein B dimerisation domain HTH_23 PF13384.6 KFR08652.1 - 0.01 15.6 0.0 0.071 12.9 0.0 2.4 3 0 0 3 3 3 0 Homeodomain-like domain HTH_Tnp_1 PF01527.20 KFR08652.1 - 0.031 14.6 0.1 0.11 12.8 0.1 2.0 1 0 0 1 1 1 0 Transposase DDE_3 PF13358.6 KFR08652.1 - 0.035 13.9 0.0 2.5 7.9 0.1 2.3 2 0 0 2 2 2 0 DDE superfamily endonuclease UPF0122 PF04297.14 KFR08652.1 - 0.13 12.5 0.1 0.36 11.1 0.1 1.7 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like Arfaptin PF06456.13 KFR08653.1 - 4.5e-82 275.1 9.6 6.2e-82 274.6 9.6 1.1 1 0 0 1 1 1 1 Arfaptin-like domain TPR_MLP1_2 PF07926.12 KFR08653.1 - 0.048 13.7 5.3 3.3 7.8 0.9 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DHR10 PF18595.1 KFR08653.1 - 6.4 6.9 10.8 0.34 11.0 1.1 2.6 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain FH2 PF02181.23 KFR08654.1 - 2.6e-93 313.1 7.1 3.8e-93 312.6 7.1 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain NHL PF01436.21 KFR08655.1 - 4.8e-52 171.5 19.8 8.9e-10 38.1 0.2 6.6 6 0 0 6 6 6 6 NHL repeat DUF5128 PF17170.4 KFR08655.1 - 1.2e-19 70.6 8.7 1.2e-08 34.5 0.4 4.1 2 2 1 3 3 3 3 6-bladed beta-propeller Filamin PF00630.19 KFR08655.1 - 1e-17 64.8 0.0 3.9e-17 63.0 0.0 2.1 2 0 0 2 2 1 1 Filamin/ABP280 repeat SGL PF08450.12 KFR08655.1 - 6.4e-12 45.6 3.4 0.00011 21.9 0.1 5.6 1 1 4 6 6 6 3 SMP-30/Gluconolactonase/LRE-like region zf-B_box PF00643.24 KFR08655.1 - 9.3e-11 41.7 3.3 9.3e-11 41.7 3.3 2.9 3 1 0 3 3 1 1 B-box zinc finger zf-RING_UBOX PF13445.6 KFR08655.1 - 5.9e-10 39.0 5.8 5.9e-10 39.0 5.8 2.5 2 1 1 3 3 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFR08655.1 - 2e-08 33.9 10.0 2e-08 33.9 10.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFR08655.1 - 5.1e-08 32.6 10.2 5.1e-08 32.6 10.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFR08655.1 - 1.2e-07 31.4 7.8 1.2e-07 31.4 7.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFR08655.1 - 5.2e-07 29.5 8.5 5.2e-07 29.5 8.5 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFR08655.1 - 7e-07 29.5 9.6 7e-07 29.5 9.6 2.6 2 0 0 2 2 2 1 Ring finger domain DUF4934 PF16288.5 KFR08655.1 - 1.7e-06 27.8 2.0 0.053 13.4 0.4 3.4 2 1 1 3 3 3 3 Domain of unknown function (DUF4934) Prok-RING_4 PF14447.6 KFR08655.1 - 1.5e-05 24.7 8.8 1.5e-05 24.7 8.8 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFR08655.1 - 0.0001 22.4 11.1 0.0001 22.4 11.1 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KFR08655.1 - 0.0065 16.5 1.4 0.017 15.2 1.4 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger SBBP PF06739.11 KFR08655.1 - 0.0076 16.2 1.7 0.5 10.4 0.3 3.4 4 0 0 4 4 3 1 Beta-propeller repeat Caskin-tail PF16632.5 KFR08655.1 - 0.011 16.2 0.5 0.024 15.0 0.5 1.6 1 0 0 1 1 1 0 C-terminal region of Caskin Invasin_D3 PF09134.10 KFR08655.1 - 0.013 15.7 0.0 0.047 14.0 0.0 1.9 1 0 0 1 1 1 0 Invasin, domain 3 Ldl_recept_b PF00058.17 KFR08655.1 - 0.026 15.0 0.0 28 5.3 0.0 3.9 4 0 0 4 4 4 0 Low-density lipoprotein receptor repeat class B zf-RING_11 PF17123.5 KFR08655.1 - 0.032 14.0 3.9 0.089 12.6 3.9 1.8 1 0 0 1 1 1 0 RING-like zinc finger Cadherin_5 PF17892.1 KFR08655.1 - 0.22 11.5 0.9 0.48 10.4 0.0 2.1 2 0 0 2 2 1 0 Cadherin-like domain NPV_P10 PF05531.12 KFR08655.1 - 0.8 10.2 2.9 1.5 9.3 1.5 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein VCBS PF13517.6 KFR08655.1 - 3 8.5 9.0 27 5.4 0.1 4.5 2 1 3 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella zf-RING_10 PF16685.5 KFR08655.1 - 3.2 8.0 11.7 4.4 7.5 4.7 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 Mnd1 PF03962.15 KFR08656.1 - 2.2e-29 101.5 0.2 2.2e-29 101.5 0.2 2.2 3 0 0 3 3 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 KFR08656.1 - 4.8e-24 84.2 1.3 4.8e-24 84.2 1.3 2.5 3 0 0 3 3 3 1 Leucine zipper with capping helix domain DivIC PF04977.15 KFR08656.1 - 4.1e-07 29.7 11.2 0.00017 21.3 2.0 3.3 1 1 2 3 3 3 3 Septum formation initiator Penicillinase_R PF03965.16 KFR08656.1 - 1.8e-06 28.3 0.5 3.4e-06 27.4 0.5 1.4 1 0 0 1 1 1 1 Penicillinase repressor FapA PF03961.13 KFR08656.1 - 0.021 13.4 4.2 0.031 12.9 4.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A SHE3 PF17078.5 KFR08656.1 - 0.041 13.6 6.7 0.063 13.0 6.7 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 GAS PF13851.6 KFR08656.1 - 0.084 12.2 9.7 0.15 11.4 9.7 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DsrD PF08679.11 KFR08656.1 - 0.088 13.1 0.1 0.088 13.1 0.1 2.3 3 0 0 3 3 2 0 Dissimilatory sulfite reductase D (DsrD) TrmB PF01978.19 KFR08656.1 - 0.099 12.5 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DASH_Spc19 PF08287.11 KFR08656.1 - 0.25 11.2 9.3 0.46 10.4 9.3 1.4 1 0 0 1 1 1 0 Spc19 APG6_N PF17675.1 KFR08656.1 - 0.34 11.5 12.8 0.58 10.7 12.8 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4200 PF13863.6 KFR08656.1 - 0.72 10.3 15.0 5.7 7.4 15.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) ABC_tran_CTD PF16326.5 KFR08656.1 - 1.8 8.9 15.8 1.5 9.2 13.3 2.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain Spc7 PF08317.11 KFR08656.1 - 2.6 6.8 17.6 0.16 10.8 2.2 2.4 2 1 1 3 3 3 0 Spc7 kinetochore protein ZapB PF06005.12 KFR08656.1 - 2.9 8.4 14.2 1 9.9 3.2 2.3 1 1 1 2 2 2 0 Cell division protein ZapB DUF4140 PF13600.6 KFR08656.1 - 4 7.9 9.5 7.1 7.1 0.6 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) TPR_MLP1_2 PF07926.12 KFR08656.1 - 4 7.5 15.8 0.9 9.6 2.5 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein AAA_23 PF13476.6 KFR08656.1 - 6.5 7.2 12.3 10 6.6 12.4 1.4 1 1 0 1 1 1 0 AAA domain Seryl_tRNA_N PF02403.22 KFR08656.1 - 7.6 6.8 13.4 4.1 7.7 3.2 1.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMEM131_like PF12371.8 KFR08657.1 - 1.4e-17 63.7 0.9 1.7e-16 60.3 0.2 3.0 3 0 0 3 3 3 1 Transmembrane protein 131-like ASH PF15780.5 KFR08657.1 - 2.8e-10 40.3 0.0 3.6e-06 27.1 0.0 4.4 4 0 0 4 4 4 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin LRR_8 PF13855.6 KFR08658.1 - 7.7e-39 131.3 42.8 1.1e-15 57.1 8.2 9.0 5 3 4 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 KFR08658.1 - 2.9e-22 78.4 42.9 3.6e-05 24.0 4.9 9.3 6 3 1 8 8 8 6 Leucine Rich repeats (2 copies) TIR PF01582.20 KFR08658.1 - 3.6e-22 79.0 0.6 5.6e-22 78.4 0.6 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 KFR08658.1 - 2e-15 57.5 0.2 6.1e-15 55.9 0.1 1.9 2 0 0 2 2 2 1 TIR domain LRR_9 PF14580.6 KFR08658.1 - 2.1e-07 30.6 11.1 0.0022 17.5 0.0 4.6 2 2 1 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 KFR08658.1 - 3.1e-07 30.0 40.6 0.051 14.1 0.3 12.4 8 2 1 9 9 9 2 Leucine Rich Repeat LRR_5 PF13306.6 KFR08658.1 - 3.7e-05 23.7 0.0 0.00091 19.2 0.0 3.0 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KFR08658.1 - 0.0016 18.3 32.4 3 8.1 0.2 10.8 11 0 0 11 11 11 2 Leucine Rich repeat DUF1863 PF08937.11 KFR08658.1 - 0.071 13.4 0.1 0.32 11.3 0.1 2.0 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) HTS PF04204.16 KFR08658.1 - 0.13 11.2 0.2 1.5 7.7 0.1 2.3 2 0 0 2 2 2 0 Homoserine O-succinyltransferase zf-RING_2 PF13639.6 KFR08659.1 - 0.00013 22.2 12.9 0.00045 20.5 13.0 2.0 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFR08659.1 - 0.0022 18.2 11.6 0.0058 16.9 11.6 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KFR08659.1 - 0.0086 15.9 5.4 0.0086 15.9 5.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFR08659.1 - 0.0091 15.9 10.9 0.024 14.6 10.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KFR08659.1 - 0.023 14.4 5.9 0.025 14.3 3.7 2.3 2 1 0 2 2 2 0 RING-like zinc finger zf-RING_UBOX PF13445.6 KFR08659.1 - 0.46 10.6 10.4 1.1 9.4 10.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 KFR08659.1 - 0.48 10.3 13.6 1.6 8.7 13.6 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFR08659.1 - 0.58 10.2 8.6 3.6 7.7 8.6 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KFR08659.1 - 3.1 7.7 11.8 14 5.7 11.8 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFR08659.1 - 3.8 7.5 12.9 31 4.5 13.0 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KFR08659.1 - 9.3 6.5 12.1 3.5e+02 1.4 12.1 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain Fz PF01392.22 KFR08660.1 - 1.5e-29 102.8 2.8 3.4e-29 101.7 2.8 1.6 1 0 0 1 1 1 1 Fz domain NTR PF01759.21 KFR08660.1 - 3.3e-12 46.2 0.2 5.6e-12 45.4 0.2 1.4 1 0 0 1 1 1 1 UNC-6/NTR/C345C module TBP PF00352.21 KFR08660.1 - 0.15 12.0 0.0 12 5.9 0.0 2.3 2 0 0 2 2 2 0 Transcription factor TFIID (or TATA-binding protein, TBP) Cadherin PF00028.17 KFR08661.1 - 3.5e-108 354.3 2.2 7.1e-20 71.3 0.0 6.3 6 0 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.12 KFR08661.1 - 3.4e-13 49.2 0.0 0.24 11.3 0.0 6.5 6 0 0 6 6 6 4 Cadherin-like Cadherin_3 PF16184.5 KFR08661.1 - 1.2e-11 44.6 8.3 0.0035 17.3 0.0 6.5 5 2 3 8 8 8 4 Cadherin-like RET_CLD1 PF17756.1 KFR08661.1 - 9.1e-05 22.7 0.5 20 5.5 0.0 5.5 4 1 0 5 5 5 1 RET Cadherin like domain 1 Cadherin_pro PF08758.11 KFR08661.1 - 0.0087 16.2 0.0 2.4 8.4 0.0 3.6 4 0 0 4 4 4 1 Cadherin prodomain like Cadherin_4 PF17803.1 KFR08661.1 - 0.032 14.9 13.3 0.25 12.0 0.1 5.2 5 1 0 5 5 5 0 Bacterial cadherin-like domain DUF3364 PF11844.8 KFR08661.1 - 0.078 13.2 2.6 49 4.3 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF3364) Big_9 PF17963.1 KFR08661.1 - 0.24 12.2 16.0 0.45 11.3 0.2 5.0 6 0 0 6 6 6 0 Bacterial Ig domain WD40 PF00400.32 KFR08663.1 - 1e-40 136.9 20.8 2e-09 37.9 0.6 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR08663.1 - 1.7e-05 25.0 4.6 0.25 11.7 0.1 4.9 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KFR08663.1 - 9.1e-05 21.4 0.6 0.73 8.5 0.0 3.7 2 1 1 4 4 4 2 Nup133 N terminal like BBS2_Mid PF14783.6 KFR08663.1 - 0.0012 18.9 0.1 6 7.0 0.0 4.3 3 1 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 KFR08663.1 - 0.0035 16.1 4.1 0.51 8.9 0.4 3.8 1 1 3 4 4 4 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KFR08663.1 - 0.062 12.6 0.0 0.28 10.5 0.0 2.0 2 1 1 3 3 3 0 WD40-like domain Fibrinogen_C PF00147.18 KFR08664.1 - 6.7e-101 336.7 13.4 9.6e-101 336.2 13.4 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fib_alpha PF08702.10 KFR08664.1 - 6.5e-42 143.1 3.0 8.7e-42 142.7 3.0 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF1465 PF07323.12 KFR08664.1 - 0.0013 18.6 1.2 0.048 13.5 0.2 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1465) DUF5082 PF16888.5 KFR08664.1 - 0.01 16.1 6.4 0.059 13.7 2.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) EF-hand_6 PF13405.6 KFR08664.1 - 0.076 13.0 0.3 0.64 10.1 0.3 2.4 2 0 0 2 2 2 0 EF-hand domain DNA_methylase PF00145.17 KFR08664.1 - 0.097 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase DUF1664 PF07889.12 KFR08664.1 - 0.13 12.3 1.2 0.29 11.2 1.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Bacillus_HBL PF05791.11 KFR08664.1 - 0.64 9.8 5.1 4.1 7.2 3.0 2.4 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Fibrinogen_C PF00147.18 KFR08665.1 - 1.6e-34 119.7 0.6 1.7e-34 119.5 0.6 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fib_alpha PF08702.10 KFR08666.1 - 3e-43 147.4 4.6 3e-43 147.4 4.6 1.8 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family DUF2935 PF11155.8 KFR08666.1 - 0.005 17.2 0.4 0.026 14.9 0.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF2935) Cu-oxidase_4 PF02578.15 KFR08666.1 - 0.028 14.0 0.5 3.5 7.2 0.0 2.2 1 1 1 2 2 2 0 Multi-copper polyphenol oxidoreductase laccase TGF_beta PF00019.20 KFR08666.1 - 0.052 14.5 0.3 0.2 12.7 0.1 2.0 2 0 0 2 2 2 0 Transforming growth factor beta like domain DUF4407 PF14362.6 KFR08666.1 - 0.22 10.9 5.5 0.65 9.3 5.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF16 PF01519.16 KFR08666.1 - 4.6 7.8 9.2 53 4.4 9.2 2.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 AtuA PF07287.11 KFR08667.1 - 2.5e-95 319.2 0.0 2.9e-95 319.0 0.0 1.0 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA LRAT PF04970.13 KFR08668.1 - 2.6e-26 92.4 0.0 3.3e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Lecithin retinol acyltransferase RRM_1 PF00076.22 KFR08669.1 - 1.9e-36 123.7 2.1 7.9e-14 51.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DND1_DSRM PF14709.7 KFR08669.1 - 6.7e-25 87.2 0.0 1.8e-24 85.8 0.0 1.8 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 RRM_7 PF16367.5 KFR08669.1 - 2.5e-06 27.5 2.6 0.035 14.2 0.1 4.0 2 2 1 3 3 3 2 RNA recognition motif RRM_5 PF13893.6 KFR08669.1 - 0.018 14.6 0.1 8.2 6.0 0.1 2.6 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 7tm_1 PF00001.21 KFR08670.1 - 2.6e-54 184.3 14.7 3.4e-54 183.9 14.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR08670.1 - 7.5e-15 55.0 13.9 1e-14 54.5 13.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFR08670.1 - 3.8e-06 26.7 8.7 3.8e-06 26.7 8.7 1.8 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFR08670.1 - 6.6e-05 22.8 15.5 9.4e-05 22.3 15.5 1.2 1 0 0 1 1 1 1 Olfactory receptor DUF5409 PF17421.2 KFR08670.1 - 0.72 10.6 0.1 0.72 10.6 0.1 2.8 4 0 0 4 4 4 0 Family of unknown function (DUF5409) DUF4207 PF13904.6 KFR08671.1 - 0.067 12.9 90.3 0.23 11.1 54.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4207) Methyltransf_29 PF03141.16 KFR08671.1 - 4 5.9 25.3 9.6 4.6 25.3 1.6 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase AHJR-like PF18743.1 KFR08672.1 - 0.0084 15.7 0.3 0.011 15.3 0.3 1.2 1 0 0 1 1 1 1 REase_AHJR-like DUF3218 PF11508.8 KFR08672.1 - 0.15 11.5 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3218) Guanylate_cyc PF00211.20 KFR08673.1 - 3.4e-63 212.6 0.0 5.4e-63 211.9 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KFR08673.1 - 3.3e-46 157.5 2.3 2.8e-44 151.2 2.3 2.3 1 1 0 1 1 1 1 Heme NO binding associated HNOB PF07700.15 KFR08673.1 - 1.3e-06 28.5 0.0 2.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Haem-NO-binding Guanylate_cyc PF00211.20 KFR08674.1 - 1.2e-65 220.6 0.0 1.7e-65 220.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KFR08674.1 - 2.8e-57 193.7 0.0 6.3e-57 192.5 0.0 1.6 1 1 0 1 1 1 1 Heme NO binding associated HNOB PF07700.15 KFR08674.1 - 6.9e-46 156.2 0.0 1e-45 155.6 0.0 1.3 1 0 0 1 1 1 1 Haem-NO-binding Trp_dioxygenase PF03301.13 KFR08676.1 - 5.9e-163 542.2 5.3 6.9e-163 541.9 5.3 1.0 1 0 0 1 1 1 1 Tryptophan 2,3-dioxygenase Peptidase_C1 PF00112.23 KFR08677.1 - 2.6e-58 197.7 4.5 3e-58 197.5 4.5 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KFR08677.1 - 1.8e-07 30.3 0.2 0.00057 18.8 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Inhibitor_I29 PF08246.12 KFR08677.1 - 0.11 12.9 0.7 0.21 12.0 0.2 1.7 2 0 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) CUB PF00431.20 KFR08678.1 - 1e-17 64.5 0.0 1.7e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 CUB domain PDGF PF00341.17 KFR08678.1 - 1.9e-13 50.5 12.4 2.9e-13 49.9 12.4 1.3 1 0 0 1 1 1 1 PDGF/VEGF domain Neur_chan_LBD PF02931.23 KFR08679.1 - 4.5e-53 179.9 0.2 5.7e-53 179.5 0.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFR08679.1 - 5.6e-35 121.5 0.0 1.1e-34 120.6 0.0 1.4 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF3267 PF11667.8 KFR08679.1 - 0.0091 16.3 1.8 0.12 12.7 1.8 2.3 1 1 0 1 1 1 1 Putative zincin peptidase FAM198 PF15051.6 KFR08680.1 - 1.3e-147 490.9 1.6 1.5e-147 490.6 1.6 1.1 1 0 0 1 1 1 1 FAM198 protein TMEM144 PF07857.12 KFR08681.1 - 2.3e-131 437.8 15.9 2.6e-131 437.6 15.9 1.0 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 KFR08681.1 - 5.9e-12 45.5 12.0 8.4e-11 41.7 3.3 2.4 2 0 0 2 2 2 2 Sugar transport protein Hormone_4 PF00220.17 KFR08681.1 - 2.7 8.2 4.9 0.69 10.0 0.6 2.3 2 0 0 2 2 2 0 Neurohypophysial hormones, N-terminal Domain LRR_8 PF13855.6 KFR08682.1 - 3e-43 145.4 30.4 4.9e-14 51.8 5.0 5.4 2 2 3 5 5 5 5 Leucine rich repeat 7tm_1 PF00001.21 KFR08682.1 - 3.8e-26 92.0 17.7 5.6e-26 91.4 17.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_5 PF13306.6 KFR08682.1 - 1.4e-18 67.1 5.8 1.2e-08 35.0 1.3 2.5 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFR08682.1 - 1.5e-17 63.4 31.7 1e-06 28.9 3.3 6.6 3 1 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFR08682.1 - 7.4e-10 38.6 18.6 0.0031 17.0 0.6 4.1 1 1 3 4 4 4 4 Leucine-rich repeat Ldl_recept_a PF00057.18 KFR08682.1 - 5.2e-07 29.8 5.6 5.2e-07 29.8 5.6 2.3 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A LRRNT PF01462.18 KFR08682.1 - 0.00017 21.2 0.1 0.00039 20.0 0.1 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KFR08682.1 - 0.067 13.8 25.9 2 9.3 0.1 8.7 9 1 1 10 10 10 0 Leucine Rich Repeat LRR_6 PF13516.6 KFR08682.1 - 0.75 10.0 14.4 36 4.8 0.3 6.2 6 0 0 6 6 6 0 Leucine Rich repeat RCDG1 PF15725.5 KFR08683.1 - 4.8e-18 65.4 0.7 5.9e-18 65.1 0.7 1.1 1 0 0 1 1 1 1 Renal cancer differentiation gene 1 protein ETF_QO PF05187.13 KFR08684.1 - 9.6e-49 163.9 0.0 1.6e-48 163.1 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 KFR08684.1 - 1.8e-09 37.7 0.2 2e-05 24.4 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 KFR08684.1 - 3.1e-08 33.1 0.0 1.1e-05 24.8 0.0 2.1 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.24 KFR08684.1 - 3.4e-08 33.0 0.6 3.8e-05 23.0 1.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KFR08684.1 - 8.7e-07 29.1 0.1 6.1e-06 26.4 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFR08684.1 - 2.8e-06 26.8 0.0 3.6e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFR08684.1 - 1.7e-05 24.2 0.1 4.1e-05 23.0 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KFR08684.1 - 6.3e-05 22.2 0.1 9e-05 21.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KFR08684.1 - 0.0001 22.3 0.0 0.00036 20.6 0.1 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KFR08684.1 - 0.0002 20.2 0.5 0.00029 19.7 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KFR08684.1 - 0.00048 20.6 0.0 0.45 11.1 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFR08684.1 - 0.0026 17.1 0.2 0.0041 16.4 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KFR08684.1 - 0.0034 16.3 0.1 0.028 13.3 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.7 KFR08684.1 - 0.0057 16.1 0.1 0.0087 15.5 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KFR08684.1 - 0.02 14.0 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 KFR08684.1 - 0.043 12.9 0.3 0.07 12.2 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KFR08684.1 - 0.044 13.1 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fer4_7 PF12838.7 KFR08684.1 - 0.11 13.1 0.5 0.29 11.8 0.5 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Pro_isomerase PF00160.21 KFR08685.1 - 6.3e-46 156.5 0.5 7e-46 156.4 0.5 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.6 KFR08685.1 - 0.12 12.4 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin domain FNIP_M PF14637.6 KFR08686.1 - 7.6e-92 307.4 0.6 1.3e-91 306.6 0.6 1.4 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain FNIP_C PF14638.6 KFR08686.1 - 1.1e-72 243.7 0.5 2.6e-72 242.5 0.5 1.6 1 0 0 1 1 1 1 Folliculin-interacting protein C-terminus FNIP_N PF14636.6 KFR08686.1 - 2e-27 97.1 1.5 2e-27 97.1 1.5 4.3 3 2 0 3 3 3 1 Folliculin-interacting protein N-terminus RasGEF_N PF00618.20 KFR08687.1 - 3.5e-13 49.7 0.2 8.9e-12 45.2 0.2 2.5 1 1 0 1 1 1 1 RasGEF N-terminal motif RA PF00788.23 KFR08687.1 - 3.5e-11 43.6 0.0 1.1e-10 42.0 0.0 1.9 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PDZ PF00595.24 KFR08687.1 - 1.1e-10 41.8 0.0 2.1e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFR08687.1 - 1.1e-09 38.0 0.0 2.3e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain cNMP_binding PF00027.29 KFR08687.1 - 2e-07 31.0 0.0 0.00015 21.8 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PDZ_2 PF13180.6 KFR08687.1 - 6.9e-05 23.1 0.0 0.00021 21.5 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Ig_3 PF13927.6 KFR08691.1 - 1.2e-30 105.9 0.9 6.3e-16 58.7 0.1 3.1 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFR08691.1 - 2.5e-29 101.2 0.0 3.7e-15 55.8 0.0 3.3 4 0 0 4 4 4 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFR08691.1 - 1.7e-19 70.0 0.1 2.2e-08 34.3 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFR08691.1 - 2.7e-18 65.9 0.4 2.4e-07 30.8 0.0 3.8 4 0 0 4 4 4 2 Immunoglobulin domain Kazal_2 PF07648.15 KFR08691.1 - 6.5e-08 32.6 6.1 6.5e-08 32.6 6.1 2.4 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain V-set PF07686.17 KFR08691.1 - 4.1e-07 30.1 4.5 0.064 13.4 0.1 4.4 2 2 0 2 2 2 2 Immunoglobulin V-set domain Kazal_1 PF00050.21 KFR08691.1 - 4.9e-05 23.3 7.2 8e-05 22.6 6.1 1.9 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.6 KFR08691.1 - 0.00059 20.2 4.5 0.0018 18.7 4.5 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFR08691.1 - 0.00077 18.8 0.4 0.0028 17.1 0.2 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KFR08691.1 - 0.0017 18.1 0.7 0.028 14.3 0.3 2.9 2 0 0 2 2 2 1 EF-hand domain C2-set_2 PF08205.12 KFR08691.1 - 0.0022 18.0 0.6 3.1 7.9 0.0 3.2 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFR08691.1 - 0.0032 17.0 0.0 0.61 9.7 0.0 2.8 2 0 0 2 2 2 1 Immunoglobulin domain C1-set PF07654.15 KFR08691.1 - 0.01 16.2 0.0 0.46 10.9 0.0 2.9 2 0 0 2 2 2 1 Immunoglobulin C1-set domain SPARC_Ca_bdg PF10591.9 KFR08691.1 - 0.011 16.0 1.4 0.026 14.8 1.0 1.8 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Gar1 PF04410.14 KFR08692.1 - 8.2e-46 155.6 0.3 1.3e-45 155.0 0.3 1.3 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region 7tm_1 PF00001.21 KFR08694.1 - 2e-54 184.7 20.6 2.5e-54 184.3 20.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR08694.1 - 1.2e-09 37.9 20.5 1.9e-09 37.3 20.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFR08694.1 - 0.00011 21.9 14.3 0.00011 21.9 14.3 2.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Git3 PF11710.8 KFR08694.1 - 0.022 14.5 10.6 0.062 13.1 10.6 1.7 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 TRP PF06011.12 KFR08694.1 - 0.45 9.2 15.0 0.52 9.0 4.9 2.5 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel PLAC8 PF04749.17 KFR08694.1 - 7.4 7.7 9.7 9.3 7.3 0.0 3.0 3 1 0 3 3 3 0 PLAC8 family Tma16 PF11176.8 KFR08695.1 - 1.3e-46 158.1 6.4 1.6e-46 157.8 6.4 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 HipN PF18253.1 KFR08695.1 - 0.016 14.9 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Hsp70-interacting protein N N-terminal domain Use1 PF09753.9 KFR08695.1 - 0.072 12.8 5.8 0.12 12.1 5.8 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 Ion_trans_N PF08412.10 KFR08695.1 - 1.4 8.6 0.0 1.4 8.6 0.0 2.6 4 0 0 4 4 4 0 Ion transport protein N-terminal RINGv PF12906.7 KFR08696.1 - 6e-16 58.3 15.7 1.7e-15 56.9 15.7 1.8 1 0 0 1 1 1 1 RING-variant domain TMEM192 PF14802.6 KFR08697.1 - 2.2e-85 285.5 2.8 2.5e-85 285.3 2.8 1.0 1 0 0 1 1 1 1 TMEM192 family PAP2 PF01569.21 KFR08697.1 - 0.019 14.7 1.2 0.31 10.8 0.2 2.5 2 1 0 2 2 2 0 PAP2 superfamily Kelch_1 PF01344.25 KFR08698.1 - 1.6e-88 290.1 26.3 1.3e-16 59.9 1.9 6.6 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 KFR08698.1 - 1.8e-40 135.9 4.2 9.4e-08 32.1 0.0 6.3 4 2 2 6 6 6 6 Kelch motif BTB PF00651.31 KFR08698.1 - 8.7e-32 109.7 0.1 1.9e-31 108.5 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 KFR08698.1 - 3.2e-31 106.1 10.6 3.2e-05 23.7 0.2 6.3 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 KFR08698.1 - 1.7e-30 105.2 2.1 6.9e-30 103.2 2.1 2.1 1 1 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 KFR08698.1 - 8.4e-30 102.5 15.6 8.1e-06 26.0 0.2 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.6 KFR08698.1 - 7.8e-23 80.2 5.9 0.00059 19.8 0.1 6.4 4 1 2 6 6 6 5 Galactose oxidase, central domain PQQ_3 PF13570.6 KFR08698.1 - 0.00043 20.7 11.3 0.46 11.0 0.0 5.1 5 0 0 5 5 5 2 PQQ-like domain Kelch_5 PF13854.6 KFR08698.1 - 0.0006 19.7 17.3 0.69 10.0 0.1 5.1 5 0 0 5 5 5 4 Kelch motif FA_hydroxylase PF04116.13 KFR08699.1 - 1e-26 93.8 16.3 1e-26 93.8 16.3 1.7 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily QueT PF06177.11 KFR08699.1 - 0.079 13.3 0.9 0.83 10.0 0.0 2.5 2 1 0 2 2 2 0 QueT transporter DUF4886 PF16227.5 KFR08699.1 - 0.094 11.9 0.1 0.19 10.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4886) CLAMP PF14769.6 KFR08699.1 - 0.41 11.1 4.6 0.59 10.6 3.4 1.9 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 CUB PF00431.20 KFR08700.1 - 1.6e-188 614.3 6.9 1.5e-40 137.9 0.2 5.3 5 0 0 5 5 5 5 CUB domain Astacin PF01400.24 KFR08700.1 - 3.9e-73 245.1 0.1 9.8e-73 243.9 0.0 1.7 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) FXa_inhibition PF14670.6 KFR08700.1 - 1.3e-19 70.2 28.4 1.2e-09 38.3 9.8 3.0 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 KFR08700.1 - 2.8e-12 46.6 30.7 4.4e-07 30.0 8.5 2.9 2 0 0 2 2 2 2 Calcium-binding EGF domain cEGF PF12662.7 KFR08700.1 - 1.1e-09 38.0 7.9 4.1e-05 23.4 2.3 3.2 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF PF00008.27 KFR08700.1 - 3.5e-07 30.4 21.3 0.00065 20.0 6.7 2.9 2 0 0 2 2 2 2 EGF-like domain CUB_2 PF02408.20 KFR08700.1 - 3.1e-05 23.7 4.4 0.85 9.4 0.0 4.3 4 0 0 4 4 4 3 CUB-like domain EGF_3 PF12947.7 KFR08700.1 - 3.4e-05 24.0 24.8 0.00042 20.4 4.8 3.6 2 1 1 3 3 3 2 EGF domain hEGF PF12661.7 KFR08700.1 - 0.00028 21.4 19.9 0.068 13.8 5.5 3.1 2 0 0 2 2 2 2 Human growth factor-like EGF Peptidase_M10 PF00413.24 KFR08700.1 - 0.0023 17.8 0.1 0.72 9.7 0.0 2.6 2 0 0 2 2 2 1 Matrixin Reprolysin_4 PF13583.6 KFR08700.1 - 0.018 14.7 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like AWS PF17907.1 KFR08700.1 - 3.4 7.8 10.2 9 6.4 1.2 3.0 2 0 0 2 2 2 0 AWS domain SPARC_Ca_bdg PF10591.9 KFR08702.1 - 5.9e-34 116.8 1.8 1e-33 116.0 1.8 1.4 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Thyroglobulin_1 PF00086.18 KFR08702.1 - 8e-18 63.9 6.8 8e-18 63.9 6.8 3.2 4 0 0 4 4 4 1 Thyroglobulin type-1 repeat Kazal_2 PF07648.15 KFR08702.1 - 2.5e-13 49.9 16.5 1.8e-12 47.1 10.6 3.1 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFR08702.1 - 5.5e-06 26.3 7.6 5.5e-06 26.3 7.6 3.6 3 1 0 3 3 3 1 Kazal-type serine protease inhibitor domain TFIIA PF03153.13 KFR08702.1 - 8.2 6.3 10.7 11 5.9 10.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Annexin PF00191.20 KFR08705.1 - 5.2e-78 257.1 8.3 5.3e-21 74.5 0.2 4.1 4 0 0 4 4 4 4 Annexin RuvC_1 PF18516.1 KFR08706.1 - 0.036 13.2 1.2 0.046 12.9 1.2 1.1 1 0 0 1 1 1 0 RuvC nuclease domain PIN_2 PF10130.9 KFR08706.1 - 0.039 14.2 0.3 0.092 13.0 0.2 1.6 1 1 0 1 1 1 0 PIN domain DUF5442 PF17514.2 KFR08706.1 - 0.14 12.4 2.7 0.44 10.8 0.7 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5442) zf-B_box PF00643.24 KFR08706.1 - 1.8 8.8 5.9 0.22 11.7 0.8 2.0 2 0 0 2 2 2 0 B-box zinc finger DEAD PF00270.29 KFR08707.1 - 1.1e-17 64.3 0.1 3.8e-17 62.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KFR08707.1 - 7.2e-14 52.1 6.8 4.1e-11 43.2 0.0 4.0 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFR08707.1 - 1.7e-06 28.4 0.3 1.8e-05 25.0 0.0 2.9 1 1 0 2 2 2 1 Helicase conserved C-terminal domain Reprolysin PF01421.19 KFR08707.1 - 0.028 14.3 0.2 0.6 10.0 0.1 2.9 3 0 0 3 3 3 0 Reprolysin (M12B) family zinc metalloprotease BNIP2 PF12496.8 KFR08707.1 - 0.059 13.8 0.6 0.21 12.0 0.6 1.9 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 TAtT PF16811.5 KFR08707.1 - 0.64 9.3 4.9 0.12 11.7 0.8 1.8 2 0 0 2 2 2 0 TRAP transporter T-component DUF812 PF05667.11 KFR08707.1 - 1.4 7.7 24.5 0.021 13.7 9.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF812) I-set PF07679.16 KFR08708.1 - 5.1e-109 356.6 0.0 2.9e-22 78.5 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR08708.1 - 5e-73 241.7 0.0 1.8e-15 57.3 0.0 6.1 5 0 0 5 5 5 5 Immunoglobulin domain Ig_2 PF13895.6 KFR08708.1 - 2.6e-53 178.3 0.2 1.6e-10 41.1 0.0 5.5 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 KFR08708.1 - 5.9e-51 170.6 0.2 2.2e-09 37.4 0.0 5.7 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.17 KFR08708.1 - 1.6e-19 70.1 7.2 0.047 13.9 0.0 9.2 5 5 0 5 5 5 5 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFR08708.1 - 2e-14 53.4 1.5 0.059 13.4 0.0 6.4 5 1 0 5 5 5 5 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFR08708.1 - 8e-06 26.2 0.1 1.6 9.1 0.0 4.7 5 0 0 5 5 5 2 Immunoglobulin C1-set domain Receptor_2B4 PF11465.8 KFR08708.1 - 0.00024 21.3 0.0 0.22 11.7 0.0 4.0 5 0 0 5 5 5 1 Natural killer cell receptor 2B4 Ig_6 PF18452.1 KFR08708.1 - 0.00055 19.4 0.3 0.24 11.0 0.0 3.7 4 0 0 4 4 4 1 Immunoglobulin domain PKD_3 PF16820.5 KFR08708.1 - 0.017 14.8 0.0 8.6 6.2 0.0 3.4 3 0 0 3 3 3 0 PKD-like domain C2-set PF05790.15 KFR08708.1 - 0.031 14.5 0.2 11 6.3 0.1 4.2 4 0 0 4 4 4 0 Immunoglobulin C2-set domain adh_short_C2 PF13561.6 KFR08709.1 - 2.3e-61 207.3 1.1 2.8e-61 207.1 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFR08709.1 - 1.3e-55 187.9 3.1 1.5e-55 187.7 3.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFR08709.1 - 2.2e-17 63.5 2.3 1.1e-16 61.2 1.7 1.9 1 1 1 2 2 2 1 KR domain NAD_binding_10 PF13460.6 KFR08709.1 - 0.006 16.5 1.2 0.0084 16.0 1.2 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFR08709.1 - 0.0066 15.9 0.1 0.017 14.6 0.2 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KFR08709.1 - 0.01 16.1 0.1 0.03 14.6 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KFR08709.1 - 0.04 14.0 0.4 0.85 9.7 0.1 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SH3_9 PF14604.6 KFR08710.1 - 5.5e-54 179.8 1.3 5.3e-15 55.0 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_1 PF00018.28 KFR08710.1 - 4.4e-50 167.1 1.8 3.8e-12 45.6 0.0 4.3 4 0 0 4 4 4 4 SH3 domain SH3_2 PF07653.17 KFR08710.1 - 2.5e-35 119.9 2.0 5.5e-09 35.6 0.1 4.4 4 0 0 4 4 4 4 Variant SH3 domain zf-C3HC4 PF00097.25 KFR08710.1 - 4.2e-09 36.1 7.0 8.2e-09 35.2 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFR08710.1 - 5.8e-09 35.8 5.5 1.4e-08 34.6 5.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFR08710.1 - 7.8e-09 35.2 7.4 1.6e-08 34.2 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFR08710.1 - 1.9e-08 34.5 7.6 4.1e-08 33.4 7.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFR08710.1 - 1.3e-06 28.2 6.6 2.5e-06 27.4 6.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFR08710.1 - 1.9e-06 27.6 8.8 3.5e-06 26.8 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFR08710.1 - 0.0001 22.4 7.6 0.00021 21.4 7.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KFR08710.1 - 0.00045 19.9 5.0 0.00045 19.9 5.0 1.7 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KFR08710.1 - 0.00081 19.2 8.3 0.0059 16.4 8.7 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KFR08710.1 - 0.0073 16.0 2.8 0.02 14.6 2.8 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-Nse PF11789.8 KFR08710.1 - 0.12 12.2 2.3 0.29 11.0 2.3 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.20 KFR08710.1 - 0.13 12.1 5.2 0.25 11.1 5.2 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.7 KFR08710.1 - 0.33 11.3 3.7 0.89 9.9 3.7 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain HPIP PF15226.6 KFR08710.1 - 0.46 10.9 4.9 14 6.1 0.6 3.2 2 0 0 2 2 2 0 HCF-1 beta-propeller-interacting protein family Trm112p PF03966.16 KFR08710.1 - 1.7 9.3 5.9 5.4 7.7 5.9 1.9 1 0 0 1 1 1 0 Trm112p-like protein Voltage_CLC PF00654.20 KFR08711.1 - 1.5e-105 353.3 20.4 2.3e-105 352.7 20.4 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 KFR08711.1 - 8.3e-14 51.8 0.5 7.1e-07 29.6 0.1 2.5 2 0 0 2 2 2 2 CBS domain DUF2228 PF10228.9 KFR08712.1 - 5.4e-106 353.9 0.3 8.7e-106 353.3 0.3 1.3 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2228) Nrf1_DNA-bind PF10491.9 KFR08712.1 - 0.12 12.1 0.2 0.33 10.6 0.1 1.8 2 0 0 2 2 2 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 I-set PF07679.16 KFR08713.1 - 1.2e-06 28.5 0.0 3.2e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR08713.1 - 7.5e-05 23.3 0.1 0.00023 21.7 0.1 1.8 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFR08713.1 - 0.00071 19.7 0.1 0.002 18.3 0.1 1.8 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFR08713.1 - 0.0028 17.8 0.1 0.0066 16.6 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFR08713.1 - 0.0029 17.9 0.1 0.006 16.9 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain DUF5362 PF17319.2 KFR08713.1 - 0.0094 15.8 0.9 0.02 14.7 0.8 1.6 1 1 0 1 1 1 1 Family of unknown function (DUF5362) DUF4446 PF14584.6 KFR08713.1 - 0.071 13.1 0.8 0.13 12.2 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Ig_6 PF18452.1 KFR08713.1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Glycos_transf_2 PF00535.26 KFR08714.1 - 1.5e-08 34.7 0.0 2.1e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFR08715.1 - 1.3e-24 86.9 0.9 1.7e-24 86.4 0.9 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glycos_transf_2 PF00535.26 KFR08715.1 - 1.3e-16 60.9 0.0 2.4e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 KFR08715.1 - 7.6e-06 25.5 0.3 1.8e-05 24.3 0.3 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KFR08715.1 - 0.0051 16.3 0.0 0.038 13.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.6 KFR08715.1 - 0.13 13.0 0.0 14 6.5 0.0 2.4 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Glycos_transf_2 PF00535.26 KFR08716.1 - 5.4e-25 88.2 0.0 8.8e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFR08716.1 - 2.7e-23 82.6 1.2 4.5e-23 81.9 1.2 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 KFR08716.1 - 5.9e-05 23.1 0.0 9.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KFR08716.1 - 0.00064 19.3 0.0 0.0018 17.9 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase HMG_box PF00505.19 KFR08717.1 - 1.5e-28 99.0 9.7 6.2e-26 90.6 1.5 2.5 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KFR08717.1 - 2.9e-22 79.0 9.1 7.3e-15 55.3 0.9 2.4 2 0 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.6 KFR08717.1 - 0.058 13.4 10.1 0.19 11.7 1.2 2.3 2 0 0 2 2 2 0 HMG (high mobility group) box 5 Nucleo_P87 PF07267.11 KFR08717.1 - 0.14 11.0 6.4 0.13 11.1 6.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 YABBY PF04690.13 KFR08717.1 - 5.5 7.5 5.8 0.96 10.0 0.6 2.0 1 1 1 2 2 2 0 YABBY protein SAP30_Sin3_bdg PF13867.6 KFR08718.1 - 2.5e-23 82.1 0.1 3.9e-23 81.5 0.1 1.3 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 zf-SAP30 PF13866.6 KFR08718.1 - 2.6e-13 49.9 1.3 6.1e-13 48.7 1.2 1.7 2 0 0 2 2 2 1 SAP30 zinc-finger SCRG1 PF15224.6 KFR08719.1 - 1.2e-48 163.1 5.3 1.4e-48 162.9 5.3 1.0 1 0 0 1 1 1 1 Scrapie-responsive protein 1 HLH PF00010.26 KFR08720.1 - 1.1e-18 67.0 0.5 1.1e-18 67.0 0.5 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain HTH_51 PF18558.1 KFR08720.1 - 0.098 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF733 PF05306.11 KFR08720.1 - 1.1 9.6 7.4 0.073 13.4 2.6 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF733) Sec7 PF01369.20 KFR08721.1 - 1.1e-39 136.1 0.1 1.5e-39 135.6 0.1 1.1 1 0 0 1 1 1 1 Sec7 domain F-box-like PF12937.7 KFR08721.1 - 3.3e-07 30.1 0.5 8.4e-07 28.8 0.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFR08721.1 - 0.0046 16.8 1.3 0.0085 16.0 0.2 2.0 2 0 0 2 2 2 1 F-box domain CEP44 PF15007.6 KFR08722.1 - 2.7e-52 176.2 1.5 3.4e-52 175.9 0.2 1.9 2 0 0 2 2 2 1 Centrosomal spindle body, CEP44 LELP1 PF15042.6 KFR08722.1 - 0.33 11.4 1.8 0.42 11.0 0.3 1.9 2 0 0 2 2 2 0 Late cornified envelope-like proline-rich protein 1 adh_short PF00106.25 KFR08723.1 - 6.6e-46 156.2 0.0 8.1e-46 155.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFR08723.1 - 4.2e-38 131.2 0.0 5.1e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFR08723.1 - 4.6e-07 29.9 0.0 6.1e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFR08723.1 - 0.02 14.3 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Neur_chan_LBD PF02931.23 KFR08724.1 - 9.9e-52 175.5 0.1 1.5e-51 174.9 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFR08724.1 - 7.5e-38 130.9 5.3 2.3e-33 116.2 1.2 2.2 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Myelin_PLP PF01275.19 KFR08727.1 - 8.7e-92 307.3 23.9 9.9e-92 307.1 23.9 1.0 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) DUF2701 PF10857.8 KFR08727.1 - 0.11 12.6 2.1 0.33 11.0 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2701) WD40 PF00400.32 KFR08729.1 - 1.2e-32 111.4 35.8 5.8e-07 30.1 0.2 10.6 12 0 0 12 12 12 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR08729.1 - 7.9e-23 80.6 0.1 0.00024 21.3 0.0 6.5 3 2 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFR08729.1 - 0.002 16.8 6.8 0.84 8.2 0.0 5.6 6 1 1 7 7 7 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFR08729.1 - 0.056 12.4 0.3 4.5 6.1 0.0 3.1 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ank_2 PF12796.7 KFR08730.1 - 8.8e-43 144.8 5.6 2.9e-14 53.4 0.2 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFR08730.1 - 4.9e-30 103.5 2.3 1.5e-10 41.4 0.1 5.2 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFR08730.1 - 7.1e-27 90.5 5.8 3.3e-05 23.9 0.1 7.5 7 1 1 8 8 8 6 Ankyrin repeat Ank PF00023.30 KFR08730.1 - 1.3e-25 88.6 9.0 2.6e-06 27.6 0.2 6.7 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KFR08730.1 - 2.9e-20 72.0 4.5 1.4e-06 28.5 0.1 5.3 2 2 3 5 5 5 3 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFR08730.1 - 3.4e-10 40.1 7.5 5.9e-10 39.3 6.4 1.9 2 0 0 2 2 2 1 SOCS box SPC22 PF04573.12 KFR08731.1 - 2.6e-43 147.5 0.1 7e-43 146.1 0.1 1.6 1 1 0 1 1 1 1 Signal peptidase subunit CBM_3 PF00942.18 KFR08731.1 - 0.06 13.8 0.0 0.082 13.3 0.0 1.3 1 0 0 1 1 1 0 Cellulose binding domain PDGF PF00341.17 KFR08732.1 - 8.7e-24 83.6 6.8 8.7e-24 83.6 6.8 3.3 2 1 0 2 2 2 1 PDGF/VEGF domain CXCXC PF03128.14 KFR08732.1 - 1.2e-08 34.7 62.2 0.00059 20.1 5.0 8.9 8 0 0 8 8 8 6 CXCXC repeat zf-GRF PF06839.12 KFR08733.1 - 7.8e-36 121.9 27.1 7.6e-20 70.7 5.9 4.2 4 0 0 4 4 4 2 GRF zinc finger H2TH PF06831.14 KFR08733.1 - 2.9e-11 43.2 0.0 5.5e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain zf-RanBP PF00641.18 KFR08733.1 - 0.00014 21.0 1.4 0.00014 21.0 1.4 2.4 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Fapy_DNA_glyco PF01149.24 KFR08733.1 - 0.00026 21.6 0.0 0.00064 20.3 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain MIT_LIKE_ACTX PF17556.2 KFR08733.1 - 0.081 13.5 0.4 0.081 13.5 0.4 3.4 2 1 0 3 3 3 0 MIT-like atracotoxin family DZR PF12773.7 KFR08733.1 - 2.7 8.1 16.4 1.4 9.0 1.5 3.2 2 1 1 3 3 3 0 Double zinc ribbon zf-FPG_IleRS PF06827.14 KFR08733.1 - 3.9 7.4 11.1 1 9.3 3.5 3.7 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS Asparaginase_2 PF01112.18 KFR08734.1 - 3.5e-83 279.1 0.3 4.6e-83 278.8 0.3 1.0 1 0 0 1 1 1 1 Asparaginase DUF3444 PF11926.8 KFR08734.1 - 0.11 12.1 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3444) Ten_N PF06484.12 KFR08735.1 - 2.2e-35 123.2 4.9 2.4e-35 123.1 4.9 1.0 1 0 0 1 1 1 1 Teneurin Intracellular Region dCMP_cyt_deam_1 PF00383.23 KFR08736.1 - 1.5e-28 98.6 0.1 2.4e-28 98.0 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFR08736.1 - 8.2e-15 54.8 0.0 9.7e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC3 PF18771.1 KFR08736.1 - 0.022 14.9 0.2 0.048 13.8 0.1 1.7 2 0 0 2 2 2 0 APOBEC3 APOBEC4_like PF18774.1 KFR08736.1 - 0.037 14.0 0.3 0.1 12.6 0.2 1.6 1 1 1 2 2 2 0 APOBEC4-like -AID/APOBEC-deaminase WW PF00397.26 KFR08737.1 - 9.7e-08 32.0 0.2 1.9e-07 31.1 0.2 1.5 1 0 0 1 1 1 1 WW domain CENP-B_dimeris PF09026.10 KFR08737.1 - 2.9 8.4 0.0 2.9 8.4 0.0 3.2 3 0 0 3 3 3 0 Centromere protein B dimerisation domain PMP22_Claudin PF00822.20 KFR08738.1 - 3e-24 85.7 0.6 3.6e-24 85.5 0.6 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFR08738.1 - 2.7e-07 30.6 4.9 5e-06 26.4 4.9 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction XTBD PF11952.8 KFR08739.1 - 1.4e-22 79.3 0.0 1.9e-20 72.4 0.0 2.5 2 0 0 2 2 2 2 XRN-Two Binding Domain, XTBD ING PF12998.7 KFR08740.1 - 5.1e-12 46.3 3.8 5.1e-12 46.3 3.8 1.7 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KFR08740.1 - 2.8e-06 27.1 7.6 2.8e-06 27.1 7.6 2.3 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KFR08740.1 - 0.0026 17.3 2.8 0.007 15.9 2.8 1.8 1 0 0 1 1 1 1 PHD-finger zf-RING-like PF08746.11 KFR08740.1 - 0.011 16.0 4.9 0.15 12.4 2.6 2.6 2 0 0 2 2 2 0 RING-like domain zf-HC5HC2H PF13771.6 KFR08740.1 - 0.6 10.4 8.0 0.16 12.2 4.1 2.2 2 1 0 2 2 2 0 PHD-like zinc-binding domain RWD PF05773.22 KFR08741.1 - 1.1e-14 54.7 0.1 2.9e-14 53.4 0.0 1.7 2 0 0 2 2 2 1 RWD domain Inhibitor_I71 PF12628.7 KFR08741.1 - 0.0067 16.3 0.4 0.0086 15.9 0.4 1.1 1 0 0 1 1 1 1 Falstatin, cysteine peptidase inhibitor Foie-gras_1 PF11817.8 KFR08742.1 - 1.6e-77 260.6 0.7 3.3e-77 259.6 0.7 1.6 1 0 0 1 1 1 1 Foie gras liver health family 1 Gryzun-like PF12742.7 KFR08742.1 - 2.4e-23 81.9 0.1 1.3e-22 79.5 0.0 2.1 2 0 0 2 2 2 1 Gryzun, putative Golgi trafficking Gryzun PF07919.12 KFR08742.1 - 4.3e-10 39.0 0.1 2.6e-08 33.1 0.2 2.2 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi Prefoldin PF02996.17 KFR08742.1 - 0.061 13.2 0.1 0.38 10.7 0.1 2.3 2 0 0 2 2 2 0 Prefoldin subunit RVT_1 PF00078.27 KFR08743.1 - 0.0039 16.7 0.0 0.0062 16.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4462 PF14692.6 KFR08744.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Phosphodiest PF01663.22 KFR08745.1 - 8e-76 255.9 0.6 9.2e-76 255.7 0.6 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KFR08745.1 - 0.0017 17.7 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KFR08745.1 - 0.0033 16.9 0.0 0.0058 16.1 0.0 1.4 1 0 0 1 1 1 1 Sulfatase PglZ PF08665.12 KFR08745.1 - 0.016 15.3 0.9 0.025 14.7 0.1 1.7 2 0 0 2 2 2 0 PglZ domain DUF229 PF02995.17 KFR08745.1 - 0.038 12.6 0.0 0.049 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF1501 PF07394.12 KFR08745.1 - 0.19 10.7 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) IRF PF00605.17 KFR08746.1 - 3.8e-42 142.8 1.0 7.5e-42 141.9 1.0 1.5 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor Heme_oxygenase PF01126.20 KFR08746.1 - 0.082 12.7 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Heme oxygenase CENP-U PF13097.6 KFR08747.1 - 1.6e-57 194.4 10.1 1.6e-57 194.4 10.1 1.8 2 0 0 2 2 2 1 CENP-A nucleosome associated complex (NAC) subunit Mt_ATP-synt_B PF05405.14 KFR08747.1 - 0.0079 15.8 4.3 0.02 14.5 4.3 1.7 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Prefoldin PF02996.17 KFR08747.1 - 0.033 14.1 0.7 0.033 14.1 0.7 2.8 2 0 0 2 2 2 0 Prefoldin subunit GAS PF13851.6 KFR08747.1 - 0.067 12.5 14.9 0.1 11.9 13.2 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Sec8_exocyst PF04048.14 KFR08747.1 - 0.27 11.1 5.8 1.1 9.2 5.0 2.2 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain TSC22 PF01166.18 KFR08747.1 - 0.44 10.9 4.3 30 5.0 0.5 3.6 3 1 1 4 4 4 0 TSC-22/dip/bun family ZapB PF06005.12 KFR08747.1 - 0.53 10.8 18.1 0.6 10.6 4.2 3.1 3 0 0 3 3 3 0 Cell division protein ZapB Mod_r PF07200.13 KFR08747.1 - 0.8 9.8 14.2 6.8 6.8 10.6 2.6 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Tex_N PF09371.10 KFR08747.1 - 1 9.0 9.6 1.6 8.4 8.8 1.7 1 1 0 1 1 1 0 Tex-like protein N-terminal domain Leu_zip PF15294.6 KFR08747.1 - 1.6 8.2 16.0 0.048 13.2 8.8 2.1 2 1 0 2 2 2 0 Leucine zipper DUF4570 PF15134.6 KFR08747.1 - 3.9 7.5 11.7 0.19 11.7 3.4 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4570) ACCA PF03255.14 KFR08747.1 - 5.7 6.8 8.4 0.78 9.6 3.6 2.0 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit AAA_23 PF13476.6 KFR08747.1 - 6.4 7.2 14.2 11 6.5 14.2 1.5 1 1 0 1 1 1 0 AAA domain BRE1 PF08647.11 KFR08747.1 - 7.6 6.7 16.1 2.5 8.2 11.6 2.6 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase I_LWEQ PF01608.17 KFR08747.1 - 9 6.5 14.3 0.12 12.6 5.2 2.3 3 0 0 3 3 3 0 I/LWEQ domain V_ATPase_I PF01496.19 KFR08747.1 - 9.6 4.0 11.9 0.04 11.8 2.4 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family AMP-binding PF00501.28 KFR08748.1 - 7.5e-112 374.0 0.0 9.3e-112 373.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFR08748.1 - 2.2e-06 28.5 0.0 6e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BKACE PF05853.12 KFR08748.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme Hairy_orange PF07527.13 KFR08749.1 - 1.2e-08 35.0 0.8 2.8e-08 33.8 0.3 1.9 2 0 0 2 2 2 1 Hairy Orange Mito_carr PF00153.27 KFR08750.1 - 6.5e-58 192.7 4.0 5.9e-24 83.8 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 KFR08750.1 - 0.0085 15.3 0.1 0.24 10.6 0.0 2.1 2 0 0 2 2 2 2 Fuseless Sel1 PF08238.12 KFR08751.1 - 2.4e-27 94.8 21.2 5.1e-06 27.0 1.8 5.6 6 0 0 6 6 6 5 Sel1 repeat TENA_THI-4 PF03070.16 KFR08751.1 - 0.00016 21.6 0.1 0.015 15.1 0.0 2.1 2 0 0 2 2 2 2 TENA/THI-4/PQQC family TPR_6 PF13174.6 KFR08751.1 - 0.0007 20.1 9.2 9.7 7.1 0.8 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFR08751.1 - 0.078 13.2 11.5 0.94 9.9 0.3 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Peptidase_C78 PF07910.13 KFR08752.1 - 9.7e-53 178.8 0.1 1.6e-52 178.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase family C78 DUF4586 PF15239.6 KFR08753.1 - 6.9e-113 377.8 10.7 7.9e-113 377.6 10.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) DUF4749 PF15936.5 KFR08754.1 - 3.5e-26 92.2 0.3 6.1e-26 91.4 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4749) PDZ PF00595.24 KFR08754.1 - 4.7e-17 62.1 0.0 9.6e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain LIM PF00412.22 KFR08754.1 - 7.4e-14 51.7 3.4 1.2e-13 51.0 3.4 1.4 1 0 0 1 1 1 1 LIM domain PDZ_6 PF17820.1 KFR08754.1 - 1.6e-08 34.3 0.0 2.6e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFR08754.1 - 0.00089 19.5 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Lar_restr_allev PF14354.6 KFR08754.1 - 0.28 11.6 2.0 0.63 10.5 2.0 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar SH3_1 PF00018.28 KFR08755.1 - 1.6e-42 142.9 0.3 6.8e-14 51.2 0.0 3.5 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.6 KFR08755.1 - 1.3e-39 133.8 1.1 1.2e-14 53.9 0.1 4.2 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 KFR08755.1 - 4.1e-29 100.0 1.0 1.6e-13 50.1 0.1 3.5 3 0 0 3 3 3 3 Variant SH3 domain Sorb PF02208.16 KFR08755.1 - 6.5e-26 89.9 4.1 1.4e-22 79.2 0.3 2.7 2 0 0 2 2 2 2 Sorbin homologous domain LRR_8 PF13855.6 KFR08756.1 - 8.9e-80 262.4 172.6 1e-12 47.6 2.0 11.8 3 3 11 14 14 14 14 Leucine rich repeat LRR_4 PF12799.7 KFR08756.1 - 7.1e-31 105.7 116.7 0.00014 22.2 5.6 13.4 5 2 12 18 18 18 17 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFR08756.1 - 9.7e-27 93.5 29.3 5.8e-10 39.2 7.1 6.2 2 1 5 7 7 7 6 BspA type Leucine rich repeat region (6 copies) Tlr3_TMD PF17968.1 KFR08756.1 - 2.6e-18 65.9 3.8 6.2e-18 64.7 3.8 1.7 1 0 0 1 1 1 1 Toll-like receptor 3 trans-membrane domain LRR_9 PF14580.6 KFR08756.1 - 2e-11 43.7 39.3 0.001 18.6 0.7 7.4 1 1 5 7 7 7 6 Leucine-rich repeat TIR PF01582.20 KFR08756.1 - 3.2e-11 43.3 3.0 5e-11 42.7 3.0 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 KFR08756.1 - 1.1e-07 32.5 0.4 4e-07 30.7 0.2 2.0 2 0 0 2 2 2 1 TIR domain LRR_1 PF00560.33 KFR08756.1 - 4.4e-06 26.5 102.5 0.33 11.7 0.3 21.4 23 1 0 23 23 23 3 Leucine Rich Repeat LRRNT PF01462.18 KFR08756.1 - 0.0012 18.4 0.3 0.0061 16.2 0.3 2.3 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain DUF3719 PF12516.8 KFR08757.1 - 3e-22 78.1 0.0 1.4e-21 76.0 0.0 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3719) p450 PF00067.22 KFR08758.1 - 4.7e-127 424.5 0.0 5.5e-127 424.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Trypsin PF00089.26 KFR08759.1 - 1.8e-72 243.8 0.0 2.5e-72 243.3 0.0 1.2 1 0 0 1 1 1 1 Trypsin PAN_1 PF00024.26 KFR08759.1 - 5.9e-27 93.4 35.4 6.8e-09 35.6 0.7 4.8 5 0 0 5 5 5 4 PAN domain PAN_4 PF14295.6 KFR08759.1 - 1.6e-12 47.1 33.3 4.1e-05 23.4 1.0 6.3 6 1 1 7 7 7 4 PAN domain Trypsin_2 PF13365.6 KFR08759.1 - 1.2e-06 29.5 0.0 2.9e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFR08759.1 - 0.00011 22.6 0.1 0.00023 21.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) 7tm_1 PF00001.21 KFR08760.1 - 1.2e-41 142.9 21.6 1.4e-41 142.6 21.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFR08760.1 - 1.8e-06 27.8 24.8 4.9e-06 26.4 24.5 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFR08760.1 - 0.0096 15.7 13.8 0.35 10.6 13.8 2.1 1 1 0 1 1 1 1 Olfactory receptor DUF4233 PF14017.6 KFR08760.1 - 0.62 10.4 14.4 0.24 11.8 1.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF4233) Cadherin PF00028.17 KFR08761.1 - 0 1701.6 97.8 5.4e-24 84.5 0.3 34.3 34 0 0 34 34 34 34 Cadherin domain Laminin_G_2 PF02210.24 KFR08761.1 - 3.5e-28 98.7 0.2 2.7e-27 95.8 0.3 2.6 2 0 0 2 2 2 1 Laminin G domain Cadherin_3 PF16184.5 KFR08761.1 - 9.7e-25 86.7 60.5 0.011 15.7 0.1 20.0 22 0 0 22 22 22 8 Cadherin-like Cadherin_2 PF08266.12 KFR08761.1 - 4.8e-20 71.2 6.8 3.4 7.6 0.0 18.9 22 0 0 22 22 22 1 Cadherin-like Laminin_G_1 PF00054.23 KFR08761.1 - 9.6e-19 67.9 0.0 4.8e-18 65.6 0.0 2.4 1 0 0 1 1 1 1 Laminin G domain RET_CLD1 PF17756.1 KFR08761.1 - 4.4e-13 49.6 1.1 2.1 8.6 0.0 11.4 9 2 2 11 11 11 2 RET Cadherin like domain 1 EGF PF00008.27 KFR08761.1 - 3.5e-12 46.4 59.6 6.9e-05 23.1 9.9 4.8 5 0 0 5 5 4 3 EGF-like domain Cadherin_pro PF08758.11 KFR08761.1 - 2.8e-09 37.0 1.1 6.6 7.0 0.0 12.4 15 0 0 15 15 14 1 Cadherin prodomain like EGF_CA PF07645.15 KFR08761.1 - 9.5e-06 25.7 10.4 9.5e-06 25.7 10.4 4.5 3 1 1 4 4 4 1 Calcium-binding EGF domain Y_Y_Y PF07495.13 KFR08761.1 - 0.00044 20.2 5.9 50 3.9 0.0 10.1 12 1 0 12 12 12 0 Y_Y_Y domain MBF2 PF15868.5 KFR08761.1 - 0.006 17.1 0.6 31 5.2 0.0 6.8 6 0 0 6 6 4 0 Transcription activator MBF2 Laminin_G_3 PF13385.6 KFR08761.1 - 0.022 14.9 0.1 0.11 12.7 0.1 2.2 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily DUF3324 PF11797.8 KFR08761.1 - 0.055 13.4 2.3 6.8 6.7 0.3 4.1 3 0 0 3 3 3 0 Protein of unknown function C-terminal (DUF3324) hEGF PF12661.7 KFR08761.1 - 0.13 12.9 47.3 0.089 13.5 5.5 5.0 5 0 0 5 5 5 0 Human growth factor-like EGF Cadherin_4 PF17803.1 KFR08761.1 - 0.34 11.6 117.3 0.25 12.0 5.5 20.4 24 0 0 24 24 22 0 Bacterial cadherin-like domain SOCS PF12610.8 KFR08782.1 - 8.6e-16 58.1 2.0 8.6e-16 58.1 2.0 2.7 3 0 0 3 3 3 1 Suppressor of cytokine signalling SOCS_box PF07525.16 KFR08782.1 - 2e-09 37.7 0.1 4e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 SOCS box SH2 PF00017.24 KFR08782.1 - 5.4e-09 36.0 0.0 1.3e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 SH2 domain EF-hand_6 PF13405.6 KFR08783.1 - 1.3e-09 37.1 0.3 0.00036 20.2 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KFR08783.1 - 1.3e-08 35.2 3.3 1.9e-08 34.6 1.9 1.8 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFR08783.1 - 3.4e-07 29.4 0.4 0.0007 19.0 0.2 2.9 2 1 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KFR08783.1 - 0.00089 18.7 2.8 0.0069 15.8 0.7 2.8 2 1 1 3 3 3 1 EF hand EF-hand_8 PF13833.6 KFR08783.1 - 0.011 15.5 1.1 0.053 13.4 0.4 2.4 2 1 0 2 2 2 0 EF-hand domain pair PBECR3 PF18812.1 KFR08783.1 - 0.37 10.7 5.3 1.9 8.5 0.4 2.1 1 1 1 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 EF-hand_1 PF00036.32 KFR08784.1 - 5.9e-44 144.4 9.7 3.8e-10 38.6 0.4 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFR08784.1 - 5.9e-37 126.0 3.0 2.1e-19 69.7 0.8 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFR08784.1 - 4.7e-35 119.2 9.9 4.2e-15 55.3 0.3 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KFR08784.1 - 6e-32 106.8 5.0 1.1e-09 37.4 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFR08784.1 - 7.3e-28 94.8 6.8 1.1e-06 27.8 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KFR08784.1 - 5.6e-16 58.6 0.2 1.9e-09 37.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KFR08784.1 - 1.5e-09 37.7 0.5 4.3e-05 23.4 0.1 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFR08784.1 - 5.4e-08 33.2 0.0 0.003 17.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 KFR08784.1 - 2.1e-06 28.5 0.0 0.0008 20.3 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 KFR08784.1 - 9.8e-06 25.5 0.0 0.037 14.0 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KFR08784.1 - 2.1e-05 24.5 0.2 6.9e-05 22.9 0.1 2.0 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 KFR08784.1 - 0.00015 21.8 4.3 0.026 14.7 0.3 2.9 1 1 1 2 2 2 2 Dockerin type I domain DUF1103 PF06513.11 KFR08784.1 - 0.00074 19.2 1.6 0.00087 19.0 1.6 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.13 KFR08784.1 - 0.00078 19.4 0.8 0.65 9.9 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein TerB PF05099.13 KFR08784.1 - 0.0018 18.2 0.4 0.49 10.4 0.0 2.1 1 1 1 2 2 2 1 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.16 KFR08784.1 - 0.0039 17.5 1.2 1.5 9.2 0.1 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb4 DUF5580 PF17743.1 KFR08784.1 - 0.0052 15.4 0.0 0.0053 15.4 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 KFR08784.1 - 0.0062 16.4 0.7 0.33 10.8 0.2 2.2 1 1 1 2 2 2 1 SurA N-terminal domain Poly_export PF02563.16 KFR08784.1 - 0.0089 16.2 0.1 0.55 10.5 0.0 3.0 1 1 1 2 2 2 1 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 KFR08784.1 - 0.011 16.2 0.0 0.78 10.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4497) EF-hand_14 PF17959.1 KFR08784.1 - 0.019 15.3 0.1 8 6.9 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain SurA_N_3 PF13624.6 KFR08784.1 - 0.043 13.6 0.3 0.65 9.8 0.3 2.0 1 1 1 2 2 2 0 SurA N-terminal domain MotA_activ PF09114.10 KFR08784.1 - 0.047 13.8 0.4 0.78 9.9 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain Fe_hyd_lg_C PF02906.14 KFR08784.1 - 0.063 12.9 0.5 0.25 11.0 0.5 1.9 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain TetR_C_7 PF14246.6 KFR08784.1 - 0.066 13.2 0.1 6.8 6.8 0.0 2.7 2 1 1 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain dCache_2 PF08269.11 KFR08784.1 - 0.079 12.1 0.1 6.2 5.9 0.1 2.4 1 1 1 2 2 2 0 Cache domain RuvA_C PF07499.13 KFR08784.1 - 0.1 13.1 0.1 11 6.5 0.0 2.9 3 0 0 3 3 3 0 RuvA, C-terminal domain CMD PF02627.20 KFR08784.1 - 0.18 11.8 0.1 6.2 7.0 0.0 2.5 1 1 1 2 2 2 0 Carboxymuconolactone decarboxylase family Metallophos PF00149.28 KFR08785.1 - 1.4e-39 136.7 0.1 1.7e-39 136.4 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFR08785.1 - 1.1e-16 61.0 0.8 1.8e-16 60.3 0.4 1.6 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Lipase_GDSL PF00657.22 KFR08786.1 - 9.3e-74 247.7 0.0 7.9e-24 84.7 0.0 3.2 3 0 0 3 3 3 3 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KFR08786.1 - 1.6e-24 87.3 3.6 3.2e-09 37.5 0.7 4.6 3 3 0 3 3 3 3 GDSL-like Lipase/Acylhydrolase family DUF4278 PF14105.6 KFR08786.1 - 0.00036 20.9 3.6 0.32 11.5 0.1 4.5 3 3 0 3 3 3 1 Domain of unknown function (DUF4278) PLDc PF00614.22 KFR08786.1 - 0.069 13.4 0.5 49 4.3 0.0 3.3 3 0 0 3 3 3 0 Phospholipase D Active site motif zf-C6H2 PF15801.5 KFR08786.1 - 1.3 9.4 3.5 21 5.5 0.1 3.5 3 0 0 3 3 3 0 zf-MYND-like zinc finger, mRNA-binding bZIP_1 PF00170.21 KFR08787.1 - 5.7e-09 35.9 19.7 9.4e-09 35.3 19.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFR08787.1 - 1.1e-05 25.4 19.3 2e-05 24.6 19.3 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFR08787.1 - 3e-05 24.5 14.1 5e-05 23.7 14.1 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor ASD2 PF08687.11 KFR08787.1 - 0.0051 16.4 3.9 0.0073 15.9 3.9 1.2 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 UPF0242 PF06785.11 KFR08787.1 - 0.027 14.6 5.4 0.04 14.0 5.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF5320 PF17253.2 KFR08787.1 - 0.29 12.2 1.6 0.49 11.5 1.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5320) PEHE PF15275.6 KFR08787.1 - 1.4 9.6 8.2 0.2 12.3 3.7 1.9 2 0 0 2 2 2 0 PEHE domain APG6_N PF17675.1 KFR08787.1 - 1.6 9.3 13.9 2.9 8.4 13.9 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Spc7 PF08317.11 KFR08787.1 - 2.7 6.8 10.6 3.7 6.3 10.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Pox_G5 PF04599.12 KFR08787.1 - 4.7 6.1 4.3 6.4 5.7 4.3 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein BRE PF06113.12 KFR08788.1 - 2e-140 467.2 0.0 2.3e-140 467.0 0.0 1.0 1 0 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) UQ_con PF00179.26 KFR08788.1 - 0.013 15.1 2.7 1.5 8.4 0.1 2.7 3 0 0 3 3 3 0 Ubiquitin-conjugating enzyme Ank PF00023.30 KFR08788.1 - 0.091 13.3 0.1 5.8 7.5 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat UL17 PF17640.2 KFR08788.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized UL17 PfkB PF00294.24 KFR08789.1 - 1.2e-58 198.8 0.1 1.5e-58 198.5 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KFR08789.1 - 1.5e-06 27.8 0.0 2.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Ribosomal_L33 PF00471.20 KFR08790.1 - 0.07 13.6 0.0 0.071 13.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L33 Dicer_dimer PF03368.14 KFR08792.1 - 0.0012 19.0 0.0 0.0025 17.9 0.0 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain dsrm PF00035.26 KFR08792.1 - 0.0044 17.7 0.0 0.011 16.4 0.0 1.8 1 0 0 1 1 1 1 Double-stranded RNA binding motif Bromo_TP PF07524.13 KFR08793.1 - 6.8e-22 77.3 0.3 1.4e-21 76.3 0.0 1.6 2 0 0 2 2 2 1 Bromodomain associated MAGE_N PF12440.8 KFR08793.1 - 1.1 10.0 5.1 11 6.8 0.1 2.6 2 1 0 2 2 2 0 Melanoma associated antigen family N terminal LRR_8 PF13855.6 KFR08794.1 - 2.2e-38 129.8 39.9 1.5e-12 47.0 3.2 3.5 1 1 3 4 4 4 4 Leucine rich repeat I-set PF07679.16 KFR08794.1 - 6.3e-15 55.0 0.0 1.4e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_4 PF12799.7 KFR08794.1 - 1.3e-13 50.9 22.1 5.6e-06 26.6 1.6 4.7 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) Ig_3 PF13927.6 KFR08794.1 - 2.8e-13 50.2 0.1 1.1e-12 48.4 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain LRR_5 PF13306.6 KFR08794.1 - 2.2e-12 47.1 0.0 1.3e-10 41.4 0.0 2.2 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) ig PF00047.25 KFR08794.1 - 8e-10 38.8 0.0 1.6e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.21 KFR08794.1 - 1.6e-07 31.5 0.1 1.2e-06 28.8 0.0 2.4 2 0 0 2 2 2 1 Fibronectin type III domain LRR_9 PF14580.6 KFR08794.1 - 1e-06 28.4 6.3 0.00019 21.0 1.0 2.3 1 1 1 2 2 2 2 Leucine-rich repeat Ig_2 PF13895.6 KFR08794.1 - 8.3e-06 26.1 0.2 5.4e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain LRR_1 PF00560.33 KFR08794.1 - 0.00029 21.0 16.7 3.6 8.5 0.5 6.8 6 1 1 7 7 6 2 Leucine Rich Repeat Ig_C17orf99 PF17736.1 KFR08794.1 - 0.0013 18.8 0.1 0.035 14.1 0.0 2.5 2 0 0 2 2 2 1 C17orf99 Ig domain LRRCT PF01463.24 KFR08794.1 - 0.038 14.5 0.0 0.14 12.8 0.0 2.0 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain Mob_synth_C PF06463.13 KFR08796.1 - 3.9e-42 143.2 0.0 6e-42 142.6 0.0 1.3 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KFR08796.1 - 2.1e-32 112.8 0.1 3.1e-32 112.2 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KFR08796.1 - 5.2e-10 39.7 0.0 1e-09 38.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KFR08796.1 - 9.2e-06 25.8 0.0 2.8e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain Lipoprotein_9 PF03180.14 KFR08796.1 - 0.14 11.2 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 NLPA lipoprotein MoaC PF01967.21 KFR08797.1 - 1.4e-28 99.7 0.0 2e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 MoaC family Kinesin PF00225.23 KFR08798.1 - 3.5e-98 328.6 0.2 3.5e-98 328.6 0.2 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFR08798.1 - 5.7e-30 104.2 1.0 4e-29 101.5 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding FAD-SLDH PF12318.8 KFR08798.1 - 7.2 6.7 5.5 6.2 6.9 2.3 2.5 3 0 0 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase Ion_trans_2 PF07885.16 KFR08799.1 - 5.1e-33 112.9 17.5 1.5e-18 66.5 0.2 2.8 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KFR08799.1 - 2e-06 27.2 9.8 1.6e-05 24.3 1.0 2.4 2 1 0 2 2 2 2 Ion transport protein Ion_trans_2 PF07885.16 KFR08800.1 - 2.9e-23 81.6 8.6 2.8e-13 49.6 3.8 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans_2 PF07885.16 KFR08801.1 - 2.6e-30 104.2 19.6 8.5e-18 64.1 2.1 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 KFR08801.1 - 0.0053 16.0 10.0 0.018 14.3 0.5 2.3 2 1 0 2 2 2 2 Ion transport protein 7tm_2 PF00002.24 KFR08802.1 - 3.5e-81 272.1 24.5 5.5e-81 271.5 24.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFR08802.1 - 5.2e-16 58.7 3.9 1.3e-15 57.4 3.9 1.7 1 0 0 1 1 1 1 Hormone receptor domain Dicty_CAR PF05462.11 KFR08802.1 - 4.8e-06 25.9 17.0 9.2e-06 25.0 17.0 1.5 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Glyoxalase PF00903.25 KFR08804.1 - 7.3e-26 90.9 0.0 8.7e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KFR08804.1 - 1.5e-09 38.1 0.0 5.6e-09 36.3 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KFR08804.1 - 1.4e-06 29.0 0.0 2.3e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KFR08804.1 - 0.011 15.7 0.0 0.96 9.4 0.0 2.2 1 1 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KFR08804.1 - 0.067 13.3 0.0 0.2 11.8 0.0 1.8 2 1 0 2 2 2 0 Glyoxalase-like domain BTB PF00651.31 KFR08805.1 - 9.8e-28 96.6 0.3 4.2e-26 91.4 0.0 2.5 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFR08805.1 - 6.1e-24 84.1 0.4 1.5e-22 79.7 0.4 2.4 1 1 1 2 2 2 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 KFR08805.1 - 1.6e-22 80.0 0.1 1.1e-10 41.7 0.1 2.2 2 0 0 2 2 2 2 F5/8 type C domain DUF3342 PF11822.8 KFR08805.1 - 0.019 15.1 0.0 0.98 9.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) zf-AN1 PF01428.16 KFR08806.1 - 1.2e-08 34.9 8.0 2.8e-08 33.8 8.0 1.6 1 0 0 1 1 1 1 AN1-like Zinc finger Ig_3 PF13927.6 KFR08807.1 - 3e-72 239.2 17.9 4.7e-13 49.5 0.3 6.7 7 0 0 7 7 6 6 Immunoglobulin domain I-set PF07679.16 KFR08807.1 - 6.1e-64 212.1 0.2 4.6e-12 45.8 0.0 6.4 6 0 0 6 6 6 6 Immunoglobulin I-set domain MAM PF00629.23 KFR08807.1 - 2.1e-50 170.8 0.0 5.3e-50 169.5 0.0 1.8 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu ig PF00047.25 KFR08807.1 - 8.4e-50 166.9 5.8 8.1e-09 35.5 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin domain Ig_2 PF13895.6 KFR08807.1 - 4.1e-49 164.8 7.8 4.8e-08 33.2 0.1 6.6 6 0 0 6 6 6 6 Immunoglobulin domain V-set PF07686.17 KFR08807.1 - 1.5e-25 89.5 17.6 0.0033 17.6 0.1 11.3 7 5 2 9 9 9 5 Immunoglobulin V-set domain Ig_5 PF16681.5 KFR08807.1 - 3.4e-10 40.2 0.0 1.2 9.6 0.0 6.0 5 0 0 5 5 5 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KFR08807.1 - 5.8e-10 39.1 4.2 0.29 11.2 0.0 5.4 5 0 0 5 5 5 4 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFR08807.1 - 3.8e-09 36.7 0.1 0.43 10.9 0.0 6.0 5 1 0 5 5 5 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFR08807.1 - 2.5e-08 33.4 1.4 0.35 10.5 0.0 6.0 6 0 0 6 6 6 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFR08807.1 - 8.4e-06 25.8 0.8 9.1 6.4 0.0 5.8 6 0 0 6 6 6 1 Izumo-like Immunoglobulin domain C1-set PF07654.15 KFR08807.1 - 0.00022 21.5 0.6 1.2 9.6 0.0 4.8 4 0 0 4 4 4 1 Immunoglobulin C1-set domain CCDC-167 PF15188.6 KFR08808.1 - 5.2e-28 97.2 3.8 5.8e-28 97.1 3.8 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 FtsJ PF01728.19 KFR08809.1 - 6.6e-38 130.6 0.0 1.2e-37 129.7 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase G-patch PF01585.23 KFR08809.1 - 8.1e-13 48.1 2.3 2.2e-12 46.6 2.3 1.8 1 0 0 1 1 1 1 G-patch domain WW PF00397.26 KFR08809.1 - 0.00017 21.6 1.1 0.00074 19.6 0.0 2.3 2 0 0 2 2 2 1 WW domain mRNA_cap_enzyme PF01331.19 KFR08809.1 - 0.0027 17.5 0.1 0.007 16.2 0.1 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.21 KFR08809.1 - 0.026 14.2 0.1 0.059 13.0 0.1 1.6 1 0 0 1 1 1 0 ATP dependent DNA ligase domain G-patch_2 PF12656.7 KFR08809.1 - 0.08 13.0 3.4 0.09 12.9 1.6 2.0 2 0 0 2 2 2 0 G-patch domain zf-C3HC4_3 PF13920.6 KFR08810.1 - 9.8e-11 41.3 9.7 1.7e-10 40.6 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFR08810.1 - 7e-10 38.6 14.1 1.3e-09 37.7 12.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFR08810.1 - 6.3e-09 35.5 10.2 6.3e-09 35.5 10.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFR08810.1 - 8.9e-09 35.4 9.9 3.7e-08 33.4 7.7 2.5 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFR08810.1 - 3.6e-08 33.6 12.7 4.6e-08 33.3 11.6 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KFR08810.1 - 9.8e-08 31.9 7.1 1.6e-07 31.3 3.5 2.3 1 1 1 2 2 2 2 RING-type zinc-finger zf-RING_5 PF14634.6 KFR08810.1 - 4.8e-07 29.6 11.4 4.8e-07 29.6 11.4 1.6 2 0 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFR08810.1 - 8.2e-07 28.8 9.2 1.6e-06 27.9 9.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFR08810.1 - 2.2e-06 27.8 11.2 3.3e-05 24.1 11.2 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFR08810.1 - 0.0005 20.1 4.2 0.0011 18.9 4.2 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 KFR08810.1 - 0.00057 19.7 4.7 0.001 18.9 4.7 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KFR08810.1 - 0.013 15.6 7.6 0.023 14.8 7.6 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KFR08810.1 - 0.2 11.5 10.2 1.3 8.9 10.4 2.3 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc-ribbons_6 PF07191.12 KFR08810.1 - 0.56 10.2 8.8 0.97 9.5 8.0 1.8 1 1 0 1 1 1 0 zinc-ribbons DUF1644 PF07800.12 KFR08810.1 - 0.86 9.6 11.3 10 6.1 1.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1644) zf-RING_11 PF17123.5 KFR08810.1 - 2.2 8.1 18.3 2.3 8.0 1.0 2.8 2 1 0 2 2 2 0 RING-like zinc finger zf-C2H2_4 PF13894.6 KFR08810.1 - 5.1 8.2 10.0 14 6.8 0.7 3.4 1 1 2 3 3 3 0 C2H2-type zinc finger FHA PF00498.26 KFR08811.1 - 1.9e-16 60.2 0.0 3.1e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFR08811.1 - 1.7e-05 25.0 0.0 3.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain tRNA-synt_2c PF01411.19 KFR08812.1 - 3e-170 567.4 0.0 4.8e-170 566.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KFR08812.1 - 2.7e-07 30.6 0.7 1.9e-06 27.9 0.1 2.7 3 0 0 3 3 3 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KFR08812.1 - 4.7e-06 27.1 0.0 1.3e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 DHHA1 domain LRR_6 PF13516.6 KFR08813.1 - 8e-21 72.3 27.1 1.8e-05 24.4 0.3 8.3 9 0 0 9 9 9 6 Leucine Rich repeat LRR_8 PF13855.6 KFR08813.1 - 0.0016 18.1 19.4 0.0019 17.9 1.4 5.7 2 1 3 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 KFR08813.1 - 0.016 15.7 15.1 2 9.3 0.0 6.8 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_4 PF12799.7 KFR08813.1 - 0.034 14.6 3.4 0.034 14.6 3.4 5.9 4 1 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_3 PF07725.12 KFR08813.1 - 1.4 8.9 6.1 10 6.2 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat TMEM151 PF14857.6 KFR08814.1 - 5e-216 717.6 19.9 6.5e-216 717.2 19.9 1.1 1 0 0 1 1 1 1 TMEM151 family UAA PF08449.11 KFR08815.1 - 2.2e-78 263.5 19.8 2.7e-78 263.3 19.8 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KFR08815.1 - 3.8e-08 33.6 22.5 0.00018 21.7 15.5 2.6 2 1 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 KFR08815.1 - 0.0039 16.2 15.2 0.031 13.2 4.3 2.1 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 KFR08815.1 - 0.059 12.7 12.0 0.074 12.4 6.0 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family MNHE PF01899.16 KFR08815.1 - 0.39 10.5 4.5 0.67 9.7 0.4 2.5 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit DUF983 PF06170.12 KFR08815.1 - 5.8 7.4 8.0 0.74 10.3 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF983) HSP90 PF00183.18 KFR08816.1 - 2.3e-235 782.4 28.5 2.9e-235 782.0 28.5 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KFR08816.1 - 1.2e-12 48.3 0.0 2.7e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFR08816.1 - 1.4e-09 37.9 0.1 4.3e-09 36.3 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Med26 PF08711.11 KFR08816.1 - 1.2 9.2 6.7 1.9 8.6 0.0 3.5 4 0 0 4 4 4 0 TFIIS helical bundle-like domain Nucleoside_tran PF01733.18 KFR08817.1 - 6.2e-102 341.1 11.6 1.2e-101 340.2 11.6 1.4 1 0 0 1 1 1 1 Nucleoside transporter DUF2304 PF10066.9 KFR08817.1 - 0.022 15.0 3.1 0.022 15.0 3.1 4.6 4 1 2 6 6 6 0 Uncharacterized conserved protein (DUF2304) Spectrin PF00435.21 KFR08819.1 - 0.085 13.4 3.8 10 6.7 1.7 2.8 2 2 0 2 2 2 0 Spectrin repeat Peptidase_C2 PF00648.21 KFR08820.1 - 1.6e-127 424.7 0.0 2.1e-127 424.3 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KFR08820.1 - 2.2e-53 180.3 0.0 3.7e-53 179.6 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_8 PF13833.6 KFR08820.1 - 3.7e-07 29.9 0.4 7.3e-05 22.5 0.2 3.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KFR08820.1 - 3e-06 26.4 0.4 0.043 13.4 0.0 3.9 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 KFR08820.1 - 3.6e-06 26.5 0.4 0.0031 17.3 0.0 4.5 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.6 KFR08820.1 - 0.0013 19.2 3.4 5.8 7.5 1.2 4.0 4 1 0 4 4 4 2 EF-hand domain pair RSN1_7TM PF02714.15 KFR08821.1 - 5e-62 209.7 23.1 1.3e-61 208.4 23.1 1.7 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KFR08821.1 - 4.3e-39 134.5 0.2 6.4e-39 134.0 0.2 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KFR08821.1 - 2.7e-19 69.5 0.0 2.7e-19 69.5 0.0 5.6 6 1 1 7 7 7 1 Late exocytosis, associated with Golgi transport RRM_1 PF00076.22 KFR08821.1 - 0.085 12.7 0.1 3.9 7.4 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4006 PF13179.6 KFR08821.1 - 8 6.5 7.1 29 4.7 0.5 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF4006) Ribosomal_L14 PF00238.19 KFR08822.1 - 4.3e-17 62.3 0.0 3.4e-16 59.4 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein L14p/L23e Homeodomain PF00046.29 KFR08841.1 - 1.5e-14 53.5 0.5 2.5e-14 52.9 0.5 1.3 1 0 0 1 1 1 1 Homeodomain VHS PF00790.19 KFR08843.1 - 6.7e-45 152.4 0.0 1.2e-44 151.6 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KFR08843.1 - 1.9e-24 85.8 4.0 4e-24 84.7 4.0 1.5 1 0 0 1 1 1 1 GAT domain Heme_oxygenase PF01126.20 KFR08844.1 - 1.1e-80 270.2 1.8 1.6e-80 269.7 1.8 1.2 1 0 0 1 1 1 1 Heme oxygenase DctP PF03480.13 KFR08844.1 - 0.02 14.2 0.5 0.12 11.7 0.1 1.9 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 DUF2680 PF10925.8 KFR08844.1 - 0.032 14.2 0.1 0.21 11.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) DUF1796 PF08795.10 KFR08844.1 - 0.12 12.3 0.2 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) MCM PF00493.23 KFR08845.1 - 1.8e-100 334.6 0.0 3.1e-100 333.9 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFR08845.1 - 3e-40 137.0 0.7 5.8e-40 136.0 0.7 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFR08845.1 - 2.6e-25 88.7 0.9 7.2e-25 87.2 0.3 2.1 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 KFR08845.1 - 3.5e-18 66.1 1.2 8.4e-18 64.9 1.2 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFR08845.1 - 1.2e-06 28.1 0.0 0.00048 19.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFR08845.1 - 0.00044 20.3 0.0 0.0014 18.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFR08845.1 - 0.011 15.7 0.0 0.034 14.0 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TrmB PF01978.19 KFR08845.1 - 0.029 14.2 1.3 0.56 10.1 0.4 2.5 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Sigma54_activat PF00158.26 KFR08845.1 - 0.034 13.9 0.0 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Ras PF00071.22 KFR08846.1 - 3.5e-40 137.2 0.0 5.5e-40 136.6 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR08846.1 - 5.9e-14 52.3 0.0 1.1e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR08846.1 - 2.8e-08 33.4 0.0 3.9e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFR08846.1 - 0.00089 19.3 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFR08846.1 - 0.0016 18.0 0.0 0.0048 16.5 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFR08846.1 - 0.025 14.0 0.0 0.074 12.5 0.0 1.7 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KFR08846.1 - 0.068 12.6 0.1 0.28 10.6 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA_16 PF13191.6 KFR08846.1 - 0.1 12.9 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KFR08846.1 - 0.14 12.0 0.2 2.4 8.0 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase Globin PF00042.22 KFR08847.1 - 1.3e-22 80.4 0.2 2.2e-22 79.7 0.2 1.3 1 0 0 1 1 1 1 Globin AbiJ_NTD5 PF18865.1 KFR08847.1 - 0.06 13.2 0.0 0.24 11.3 0.0 1.9 1 1 1 2 2 2 0 AbiJ N-terminal domain 5 TPR_8 PF13181.6 KFR08847.1 - 0.085 13.1 0.1 3.3 8.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Fox-1_C PF12414.8 KFR08848.1 - 5.6e-26 90.8 6.6 5.6e-26 90.8 6.6 2.6 3 0 0 3 3 3 1 Calcitonin gene-related peptide regulator C terminal RRM_1 PF00076.22 KFR08848.1 - 1.4e-18 66.5 0.1 2.2e-18 65.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFR08848.1 - 0.037 13.6 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myosin_tail_1 PF01576.19 KFR08849.1 - 0 1686.1 312.8 0 1685.8 312.8 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_head PF00063.21 KFR08849.1 - 6.8e-300 996.2 0.3 6.8e-300 996.2 0.3 4.3 4 3 2 6 6 6 1 Myosin head (motor domain) Myosin_N PF02736.19 KFR08849.1 - 1.6e-12 47.0 1.7 4.2e-12 45.7 1.7 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain IQ PF00612.27 KFR08849.1 - 0.00038 20.0 0.1 0.0013 18.4 0.1 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif CC2-LZ PF16516.5 KFR08849.1 - 0.0047 17.3 18.9 0.0047 17.3 18.9 17.6 3 2 13 16 16 16 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator AAA_22 PF13401.6 KFR08849.1 - 0.015 15.6 0.0 0.015 15.6 0.0 6.3 4 2 4 8 8 8 0 AAA domain Thioredoxin PF00085.20 KFR08851.1 - 2.8e-28 97.9 0.1 3.3e-28 97.7 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KFR08851.1 - 3.9e-08 33.7 0.1 6.7e-07 29.7 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFR08851.1 - 1.7e-05 24.9 0.0 2.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 KFR08851.1 - 0.00025 21.1 0.1 0.00035 20.6 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_8 PF13905.6 KFR08851.1 - 0.00079 19.7 0.0 0.085 13.2 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 KFR08851.1 - 0.0061 16.5 0.0 0.0079 16.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DSBA PF01323.20 KFR08851.1 - 0.014 15.2 0.0 0.31 10.8 0.0 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_9 PF14595.6 KFR08851.1 - 0.044 13.6 0.0 0.055 13.2 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin DUF836 PF05768.14 KFR08851.1 - 0.14 12.6 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Pyr_redox_3 PF13738.6 KFR08852.1 - 1.4e-33 116.5 0.0 5e-31 108.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFR08852.1 - 8.3e-09 35.1 0.0 1.6e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFR08852.1 - 2.3e-07 30.3 0.0 2e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KFR08852.1 - 5.2e-06 26.6 0.0 1.3e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KFR08852.1 - 1.5e-05 23.9 0.0 0.009 14.8 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 KFR08852.1 - 1.9e-05 24.5 0.0 0.0054 16.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FMO-like PF00743.19 KFR08852.1 - 3.1e-05 22.6 0.0 8.3e-05 21.2 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Thi4 PF01946.17 KFR08852.1 - 0.00037 19.8 0.0 0.00077 18.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KFR08852.1 - 0.0022 18.5 0.0 0.77 10.4 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KFR08852.1 - 0.0045 16.3 0.0 2.5 7.3 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KFR08852.1 - 0.017 14.2 0.0 0.033 13.3 0.0 1.5 1 1 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KFR08852.1 - 0.03 14.3 0.1 0.12 12.4 0.1 2.0 1 1 0 1 1 1 0 FAD-NAD(P)-binding LigT_PEase PF02834.16 KFR08852.1 - 0.031 14.5 0.0 12 6.1 0.0 2.5 2 0 0 2 2 2 0 LigT like Phosphoesterase ISET-FN3_linker PF16625.5 KFR08852.1 - 0.04 14.4 0.1 0.092 13.3 0.1 1.5 1 0 0 1 1 1 0 Unstructured linking region I-set and fnIII on Brother of CDO FAD_binding_3 PF01494.19 KFR08852.1 - 0.051 12.8 0.0 0.079 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain DSPn PF14671.6 KFR08852.1 - 0.08 13.4 0.1 0.47 10.9 0.0 2.0 2 0 0 2 2 2 0 Dual specificity protein phosphatase, N-terminal half eIF-3_zeta PF05091.12 KFR08853.1 - 1.6e-216 720.3 4.3 1.8e-216 720.1 4.3 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 KFR08853.1 - 0.00037 20.1 0.0 0.0066 16.0 0.0 2.3 1 1 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus UPF0697 PF15117.6 KFR08853.1 - 0.41 10.8 2.5 14 5.8 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family UPF0697 PMP22_Claudin PF00822.20 KFR08854.1 - 1e-57 194.6 1.8 1.4e-57 194.2 1.8 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFR08854.1 - 3.1e-21 76.0 0.8 5.1e-21 75.3 0.8 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Ras PF00071.22 KFR08855.1 - 1.2e-35 122.6 0.0 1.3e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR08855.1 - 1.6e-16 60.6 0.0 3.2e-16 59.6 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR08855.1 - 0.00026 20.5 0.0 0.00029 20.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFR08855.1 - 0.00056 19.5 0.0 0.00067 19.2 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFR08855.1 - 0.017 15.2 0.0 0.027 14.6 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase EF-hand_1 PF00036.32 KFR08856.1 - 1.7e-12 45.9 6.6 1.4e-06 27.4 0.8 2.4 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 KFR08856.1 - 2.3e-12 45.8 1.1 6e-05 22.3 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFR08856.1 - 5.4e-12 46.0 0.1 7.3e-12 45.6 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFR08856.1 - 1.2e-10 40.4 1.2 1.4e-05 24.6 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KFR08856.1 - 4.2e-09 36.1 1.2 1.1e-05 25.2 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFR08856.1 - 0.066 13.5 0.0 0.095 13.0 0.0 1.3 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Skp1 PF01466.19 KFR08856.1 - 0.081 13.1 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 Skp1 family, dimerisation domain EFhand_Ca_insen PF08726.10 KFR08856.1 - 0.11 12.5 0.3 0.23 11.6 0.0 1.6 2 0 0 2 2 2 0 Ca2+ insensitive EF hand PX PF00787.24 KFR08857.1 - 8.3e-18 64.4 0.0 1.4e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 KFR08857.1 - 1.8e-14 53.4 1.6 7.3e-14 51.5 0.7 2.2 2 0 0 2 2 2 1 PB1 domain SH3_1 PF00018.28 KFR08857.1 - 3.3e-11 42.6 0.1 7.7e-11 41.4 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFR08857.1 - 1.2e-10 41.1 0.2 3.2e-10 39.7 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KFR08857.1 - 1.1e-07 31.4 0.0 4.6e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain fn3 PF00041.21 KFR08858.1 - 2.4e-13 50.2 6.3 1.8e-07 31.4 0.0 5.1 5 1 1 6 6 6 2 Fibronectin type III domain IL4Ra_N PF09238.10 KFR08858.1 - 3.9e-11 43.1 1.8 0.00021 21.5 0.0 2.9 3 0 0 3 3 3 2 Interleukin-4 receptor alpha chain, N-terminal IL6Ra-bind PF09240.10 KFR08858.1 - 5.2e-10 39.6 3.0 1.9e-05 25.0 0.0 2.5 2 0 0 2 2 2 2 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.10 KFR08858.1 - 1.1e-06 28.8 2.4 0.00062 19.9 0.0 3.3 4 0 0 4 4 4 2 Erythropoietin receptor, ligand binding Tissue_fac PF01108.17 KFR08858.1 - 6.8e-06 25.9 0.2 3.3e-05 23.7 0.0 2.2 3 0 0 3 3 3 1 Tissue factor IL2RB_N1 PF18707.1 KFR08858.1 - 0.0019 18.7 7.6 0.015 15.9 0.9 3.2 4 0 0 4 4 4 1 Interleukin-2 receptor subunit beta N-terminal domain 1 IL12p40_C PF10420.9 KFR08858.1 - 0.015 15.8 4.0 0.15 12.6 0.3 2.9 3 0 0 3 3 3 0 Cytokine interleukin-12p40 C-terminus FAM183 PF14886.6 KFR08858.1 - 0.028 15.1 0.1 0.054 14.2 0.1 1.5 1 0 0 1 1 1 0 FAM183A and FAM183B related TcdB_toxin_midC PF12255.8 KFR08858.1 - 0.12 12.4 0.7 0.26 11.3 0.7 1.5 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/C-terminal region TEX33 PF15400.6 KFR08859.1 - 1.5e-33 116.2 0.0 1.6e-33 116.1 0.0 1.0 1 0 0 1 1 1 1 Testis-expressed sequence 33 protein family Rhodanese PF00581.20 KFR08860.1 - 2e-30 105.4 0.0 6.9e-15 55.5 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain TTSSLRR PF12468.8 KFR08860.1 - 0.014 15.6 0.1 0.43 10.9 0.0 2.4 2 0 0 2 2 2 0 Type III secretion system leucine rich repeat protein Rhodanese PF00581.20 KFR08862.1 - 1.5e-31 109.1 0.0 4.1e-18 65.9 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain B12D PF06522.11 KFR08862.1 - 0.13 12.1 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit BTB_2 PF02214.22 KFR08863.1 - 6.2e-23 81.0 0.0 9.8e-23 80.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KFR08863.1 - 0.01 16.0 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Peptidase_M90 PF06167.12 KFR08863.1 - 0.064 12.9 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 zf-RING_9 PF13901.6 KFR08863.1 - 0.075 13.0 0.8 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon SAM_LFY PF01698.16 KFR08863.1 - 0.076 13.0 0.1 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 Floricaula / Leafy protein SAM domain Trypsin PF00089.26 KFR08864.1 - 2.8e-71 239.8 0.0 4.2e-71 239.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin SEA PF01390.20 KFR08864.1 - 4.2e-14 52.5 0.2 7e-14 51.8 0.2 1.3 1 0 0 1 1 1 1 SEA domain Ldl_recept_a PF00057.18 KFR08864.1 - 2.2e-13 50.2 42.9 3e-07 30.6 4.7 3.9 4 0 0 4 4 4 3 Low-density lipoprotein receptor domain class A CUB PF00431.20 KFR08864.1 - 1.1e-07 32.2 0.0 1.1e-05 25.8 0.0 2.5 2 0 0 2 2 2 1 CUB domain DUF1986 PF09342.11 KFR08864.1 - 6.7e-07 29.7 0.0 1.5e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF3709 PF12493.8 KFR08864.1 - 0.055 13.5 0.4 0.17 11.9 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3709) fn3 PF00041.21 KFR08865.1 - 8.3e-06 26.1 1.3 1.5e-05 25.2 1.3 1.5 1 1 0 1 1 1 1 Fibronectin type III domain C1q PF00386.21 KFR08866.1 - 3.5e-36 124.2 1.9 4.1e-36 124.0 1.9 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFR08866.1 - 4.8e-09 35.8 15.2 6.7e-09 35.4 15.2 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) 7tm_1 PF00001.21 KFR08867.1 - 8.2e-63 212.2 19.2 9.9e-63 211.9 19.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR08867.1 - 1.7e-11 44.0 11.9 2e-11 43.7 11.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFR08867.1 - 6.2e-08 32.6 9.9 8.1e-08 32.2 9.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFR08867.1 - 2.8e-06 26.9 5.5 2.8e-06 26.9 5.5 1.8 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.9 KFR08867.1 - 0.00025 20.4 12.2 0.046 13.0 12.2 2.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Serpentine_r_xa PF03383.15 KFR08867.1 - 0.00043 20.3 1.3 0.00043 20.3 1.3 2.8 2 1 1 3 3 3 1 Caenorhabditis serpentine receptor-like protein, class xa TAS2R PF05296.13 KFR08867.1 - 0.098 11.8 11.4 0.29 10.2 11.4 1.8 1 1 0 1 1 1 0 Taste receptor protein (TAS2R) Rab5ip PF07019.12 KFR08867.1 - 0.57 10.8 5.2 0.21 12.2 1.0 2.5 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) 7tm_4 PF13853.6 KFR08867.1 - 3.8 7.2 15.2 30 4.2 15.2 2.4 1 1 0 1 1 1 0 Olfactory receptor Ras PF00071.22 KFR08868.1 - 3.8e-54 182.7 0.0 4.3e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFR08868.1 - 2.7e-22 79.2 0.0 3.7e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFR08868.1 - 2.3e-07 30.5 0.0 3.8e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Sec7 PF01369.20 KFR08869.1 - 1.4e-69 233.5 0.0 2.2e-69 232.8 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 KFR08869.1 - 2.2e-27 95.6 0.1 3.5e-27 95.0 0.1 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFR08869.1 - 5.5e-05 23.5 0.3 0.00017 22.0 0.3 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 KFR08869.1 - 0.0035 17.6 0.0 0.34 11.2 0.1 2.4 1 1 1 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 KFR08869.1 - 0.022 14.9 0.0 0.06 13.4 0.0 1.8 1 1 0 1 1 1 0 PH domain Pilosulin PF17499.2 KFR08869.1 - 0.15 12.2 0.1 0.52 10.5 0.0 1.9 2 0 0 2 2 2 0 Ant venom peptides LRR_8 PF13855.6 KFR08870.1 - 2.4e-24 84.8 15.7 6.4e-15 54.7 2.1 3.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_5 PF13306.6 KFR08870.1 - 2.8e-07 30.6 1.1 8.6e-07 29.0 0.5 2.1 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFR08870.1 - 1.1e-06 28.8 12.9 0.007 16.8 0.1 3.8 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) fn3 PF00041.21 KFR08870.1 - 0.01 16.1 0.1 0.028 14.8 0.1 1.7 1 0 0 1 1 1 0 Fibronectin type III domain LRR_9 PF14580.6 KFR08870.1 - 0.029 13.9 1.2 0.13 11.7 0.6 2.0 1 1 1 2 2 2 0 Leucine-rich repeat CD34_antigen PF06365.12 KFR08870.1 - 0.081 12.5 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family LRR_1 PF00560.33 KFR08870.1 - 1 10.2 6.8 12 6.9 0.4 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat Fringe PF02434.16 KFR08871.1 - 3e-113 377.4 0.0 3.5e-113 377.2 0.0 1.0 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 KFR08871.1 - 0.001 18.9 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase CARD PF00619.21 KFR08872.1 - 5.3e-21 74.4 0.4 3.1e-20 72.0 0.0 2.7 3 0 0 3 3 3 1 Caspase recruitment domain Guanylate_kin PF00625.21 KFR08872.1 - 0.013 15.1 1.8 0.016 14.9 0.0 1.9 2 0 0 2 2 2 0 Guanylate kinase APG6_N PF17675.1 KFR08872.1 - 0.27 11.7 54.4 1.8 9.1 13.7 4.2 1 1 1 3 3 3 0 Apg6 coiled-coil region Mit_KHE1 PF10173.9 KFR08872.1 - 0.98 9.5 6.3 0.41 10.7 2.4 2.2 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related WD40_alt PF14077.6 KFR08872.1 - 1.3 8.9 7.9 2.1 8.3 0.1 4.0 4 0 0 4 4 4 0 Alternative WD40 repeat motif ERM PF00769.19 KFR08872.1 - 9.6 5.9 41.1 0.95 9.2 13.4 2.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family BORG_CEP PF14957.6 KFR08873.1 - 2.6e-15 57.7 1.3 1.2e-10 42.6 0.8 2.2 1 1 1 2 2 2 2 Cdc42 effector PBD PF00786.28 KFR08873.1 - 5.8e-07 29.8 0.5 1.1e-06 28.9 0.5 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain Gal-bind_lectin PF00337.22 KFR08874.1 - 1.9e-30 105.1 0.0 2.2e-30 104.9 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin Ribosomal_L19 PF01245.20 KFR08874.1 - 0.13 12.3 0.0 15 5.6 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L19 SH3_1 PF00018.28 KFR08874.1 - 0.18 11.4 0.2 6.3 6.5 0.0 2.3 2 0 0 2 2 2 0 SH3 domain VHS PF00790.19 KFR08875.1 - 2.5e-37 127.9 1.8 3.8e-36 124.0 0.0 2.5 2 1 1 3 3 3 1 VHS domain GAT PF03127.14 KFR08875.1 - 1.2e-22 80.0 6.1 1.2e-22 80.0 6.1 2.6 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 KFR08875.1 - 6.3e-21 73.7 3.7 6.3e-21 73.7 3.7 2.4 3 0 0 3 3 3 1 GGA N-GAT domain Ferritin PF00210.24 KFR08875.1 - 0.00046 20.1 1.3 0.014 15.3 1.1 2.2 2 0 0 2 2 2 1 Ferritin-like domain Elf4 PF07011.11 KFR08875.1 - 0.0025 17.7 5.1 0.07 13.0 1.5 2.4 2 0 0 2 2 2 2 Early Flowering 4 domain DNA_ligase_A_N PF04675.14 KFR08875.1 - 0.0041 17.5 2.6 2.4 8.4 0.5 2.9 2 1 1 3 3 3 2 DNA ligase N terminus DUF1910 PF08928.10 KFR08875.1 - 0.064 13.3 0.9 0.14 12.1 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) Cytochrom_C_2 PF01322.20 KFR08875.1 - 0.074 13.9 0.1 0.17 12.8 0.0 1.7 1 1 0 1 1 1 0 Cytochrome C' PCRF PF03462.18 KFR08875.1 - 0.077 12.9 4.7 0.15 11.9 4.7 1.5 1 0 0 1 1 1 0 PCRF domain RsbU_N PF08673.10 KFR08875.1 - 0.077 13.1 1.3 0.24 11.5 0.6 2.2 2 1 0 2 2 2 0 Phosphoserine phosphatase RsbU, N-terminal domain MCPsignal PF00015.21 KFR08875.1 - 0.083 12.7 2.4 0.12 12.2 2.4 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3450 PF11932.8 KFR08875.1 - 0.44 9.8 7.9 0.76 9.0 7.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DASH_Dad4 PF08650.10 KFR08875.1 - 0.71 9.9 10.4 0.17 11.9 3.6 3.1 3 1 0 3 3 3 0 DASH complex subunit Dad4 RhoGAP PF00620.27 KFR08876.1 - 2e-43 147.8 0.5 5.3e-43 146.5 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain BAR PF03114.18 KFR08876.1 - 5.4e-24 85.2 3.6 8.7e-24 84.5 3.6 1.3 1 0 0 1 1 1 1 BAR domain Hydrolase_like PF13242.6 KFR08876.1 - 3.1e-20 72.0 0.0 6.2e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 KFR08876.1 - 8.7e-08 32.4 2.4 0.00015 21.9 0.0 3.8 4 0 0 4 4 4 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFR08876.1 - 3.5e-05 24.2 0.0 0.00012 22.4 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Sec5 PF15469.6 KFR08876.1 - 0.0039 17.0 0.6 0.0089 15.9 0.6 1.6 1 0 0 1 1 1 1 Exocyst complex component Sec5 PGP_phosphatase PF09419.10 KFR08876.1 - 0.015 14.9 0.0 0.036 13.7 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase BAR_2 PF10455.9 KFR08876.1 - 0.047 12.8 2.6 0.091 11.9 2.6 1.4 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF2076 PF09849.9 KFR08876.1 - 0.1 12.6 5.3 0.25 11.4 5.3 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TRPM_tetra PF16519.5 KFR08876.1 - 0.23 11.6 1.2 27 4.9 0.2 2.6 2 0 0 2 2 2 0 Tetramerisation domain of TRPM DUF1216 PF06746.11 KFR08876.1 - 0.48 10.4 3.0 1.5 8.8 0.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1216) Gal-bind_lectin PF00337.22 KFR08877.1 - 2.5e-26 91.8 0.0 2.9e-26 91.6 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin ArfGap PF01412.18 KFR08878.1 - 8.4e-37 125.8 0.1 1.7e-36 124.8 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 KFR08878.1 - 1.8e-21 76.6 0.1 6.1e-11 42.8 0.0 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KFR08878.1 - 2.7e-06 27.8 2.5 0.00049 20.5 0.6 3.5 2 2 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 KFR08878.1 - 4.3e-06 26.9 1.1 0.023 15.0 0.0 3.0 3 1 0 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.6 KFR08878.1 - 6.8e-05 22.9 1.0 0.0062 16.6 0.1 3.1 2 2 0 2 2 2 1 PH domain EloA-BP1 PF15870.5 KFR08879.1 - 0.045 14.0 3.4 0.11 12.7 3.4 1.8 1 1 0 1 1 1 0 ElonginA binding-protein 1 NYD-SP28_assoc PF14775.6 KFR08879.1 - 0.12 12.5 0.8 0.23 11.6 0.8 1.4 1 0 0 1 1 1 0 Sperm tail C-terminal domain PH PF00169.29 KFR08880.1 - 6.7e-17 61.9 0.2 3.2e-16 59.7 0.1 2.3 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KFR08880.1 - 0.00059 20.2 5.3 0.0073 16.7 0.9 3.7 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 KFR08880.1 - 0.029 14.5 0.0 0.08 13.1 0.0 1.7 1 0 0 1 1 1 0 PH domain Zn_ribbon_2 PF12674.7 KFR08880.1 - 0.2 12.3 1.2 0.96 10.2 0.1 2.5 2 0 0 2 2 2 0 Putative zinc ribbon domain DUF1640 PF07798.11 KFR08880.1 - 0.98 9.4 33.4 4.3 7.4 11.0 4.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1640) Linker_histone PF00538.19 KFR08881.1 - 3e-14 53.1 0.1 9e-14 51.6 0.1 1.8 1 0 0 1 1 1 1 linker histone H1 and H5 family Aminotran_1_2 PF00155.21 KFR08882.1 - 2.4e-70 237.5 0.0 2.8e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFR08882.1 - 1.5e-07 30.7 0.0 3.8e-07 29.4 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KFR08882.1 - 5.9e-05 21.8 0.0 8.6e-05 21.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KFR08882.1 - 0.0026 17.1 0.1 0.0093 15.3 0.1 1.7 1 1 1 2 2 2 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KFR08882.1 - 0.053 12.8 0.2 0.34 10.2 0.2 2.0 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family ScsC_N PF18312.1 KFR08882.1 - 0.076 12.8 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain OKR_DC_1 PF01276.20 KFR08882.1 - 0.16 10.7 0.0 2 7.1 0.0 2.1 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Noggin PF05806.12 KFR08883.1 - 3.7e-30 105.4 18.4 1.4e-23 84.0 15.3 2.0 1 1 1 2 2 2 2 Noggin 7tm_1 PF00001.21 KFR08884.1 - 4.8e-50 170.3 20.4 5.6e-50 170.1 20.4 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFR08884.1 - 1e-07 31.6 15.5 8.4e-06 25.3 15.5 2.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 KFR08884.1 - 1.1e-07 31.9 11.6 2.2e-06 27.6 11.6 2.1 1 1 0 1 1 1 1 Olfactory receptor Ank PF00023.30 KFR08885.1 - 1.4e-21 75.9 7.1 2.9e-09 37.0 0.2 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 KFR08885.1 - 5.9e-18 65.2 0.2 7.1e-09 36.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFR08885.1 - 4.7e-17 62.1 0.6 6e-08 33.1 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFR08885.1 - 2e-14 53.5 1.9 1.4e-10 41.2 0.4 2.5 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFR08885.1 - 2.5e-14 51.9 2.9 4.1e-06 26.7 0.0 4.2 5 0 0 5 5 5 2 Ankyrin repeat Paf67 PF10255.9 KFR08886.1 - 1.2e-171 571.2 9.5 1.8e-171 570.6 9.5 1.3 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KFR08886.1 - 0.0027 17.7 0.4 0.056 13.6 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFR08886.1 - 0.014 15.2 0.3 0.54 10.2 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFR08886.1 - 0.028 14.6 0.1 0.08 13.2 0.1 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3585 PF12130.8 KFR08887.1 - 4.2e-47 159.7 14.7 6.8e-47 159.0 14.7 1.3 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain LIM PF00412.22 KFR08887.1 - 2.3e-08 34.2 4.0 4.2e-08 33.3 4.0 1.4 1 0 0 1 1 1 1 LIM domain CH PF00307.31 KFR08887.1 - 6.6e-07 29.5 0.0 1.2e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Roughex PF06020.11 KFR08887.1 - 0.029 13.5 4.5 0.075 12.1 4.5 1.6 1 0 0 1 1 1 0 Drosophila roughex protein UPF0193 PF05250.11 KFR08888.1 - 9.3e-68 228.3 6.5 1e-67 228.1 6.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) TMPIT PF07851.13 KFR08888.1 - 0.42 9.8 2.1 0.55 9.4 2.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein RNA_pol_Rpb6 PF01192.22 KFR08889.1 - 4.2e-16 58.6 0.2 7.4e-16 57.8 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 Sox_N PF12444.8 KFR08890.1 - 1.4e-30 106.3 0.4 1.4e-30 106.3 0.4 2.9 3 0 0 3 3 3 1 Sox developmental protein N terminal HMG_box PF00505.19 KFR08890.1 - 4.9e-25 87.7 1.5 8.5e-25 87.0 1.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFR08890.1 - 7.7e-10 39.2 0.9 7.7e-10 39.2 0.9 1.8 2 0 0 2 2 2 1 HMG-box domain Arfaptin PF06456.13 KFR08891.1 - 2e-84 282.7 1.5 3.3e-84 282.0 1.5 1.3 1 0 0 1 1 1 1 Arfaptin-like domain PDZ PF00595.24 KFR08891.1 - 3.7e-11 43.2 0.2 6.5e-11 42.4 0.2 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFR08891.1 - 4.6e-08 32.8 0.1 8.7e-08 31.9 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFR08891.1 - 7.1e-06 26.3 1.0 1.4e-05 25.3 0.1 2.0 3 0 0 3 3 3 1 PDZ domain BAR PF03114.18 KFR08891.1 - 1.6e-05 24.7 1.1 0.00025 20.8 1.2 2.3 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 KFR08891.1 - 4.3e-05 23.3 0.9 0.051 13.3 0.1 2.3 2 0 0 2 2 2 2 BAR domain of APPL family GRASP55_65 PF04495.14 KFR08891.1 - 0.025 14.9 0.0 0.69 10.2 0.0 2.3 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain MFS_1 PF07690.16 KFR08892.1 - 3e-33 115.2 22.4 3.7e-33 114.9 22.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CbtA PF09490.10 KFR08892.1 - 0.038 13.8 5.3 9.2 5.9 0.2 3.2 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtA) Ank_2 PF12796.7 KFR08893.1 - 3.3e-44 149.4 10.9 5.3e-10 39.8 0.1 4.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 KFR08893.1 - 1.4e-31 107.6 5.7 0.00015 22.1 0.1 6.9 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.6 KFR08893.1 - 2.8e-30 104.3 5.8 2.9e-08 34.1 0.0 7.0 2 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFR08893.1 - 1.2e-28 98.8 4.1 6.5e-08 32.7 0.0 6.9 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFR08893.1 - 5.5e-26 87.8 8.1 0.00046 20.4 0.1 8.7 9 1 0 9 9 9 5 Ankyrin repeat Patatin PF01734.22 KFR08893.1 - 9.7e-19 68.4 1.7 6.8e-18 65.6 1.7 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase bZIP_Maf PF03131.17 KFR08894.1 - 1.1e-32 112.4 8.4 1.4e-32 112.0 8.4 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 KFR08894.1 - 0.00031 20.8 12.5 0.0021 18.1 12.5 2.1 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFR08894.1 - 0.0077 16.3 10.2 0.0099 15.9 8.5 2.1 1 1 2 3 3 3 1 Basic region leucine zipper DUF1192 PF06698.11 KFR08894.1 - 0.02 14.9 0.1 0.02 14.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DivIC PF04977.15 KFR08894.1 - 0.027 14.2 1.1 0.027 14.2 1.1 2.2 1 1 1 2 2 2 0 Septum formation initiator Q_salvage PF10343.9 KFR08894.1 - 0.061 12.9 0.1 0.078 12.6 0.1 1.2 1 0 0 1 1 1 0 Potential Queuosine, Q, salvage protein family Cnn_1N PF07989.11 KFR08894.1 - 0.079 13.1 3.6 0.23 11.6 3.6 1.8 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 Nup54 PF13874.6 KFR08894.1 - 0.094 12.8 4.2 0.13 12.3 4.2 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 YabA PF06156.13 KFR08894.1 - 0.65 10.7 4.1 0.48 11.1 0.5 2.0 1 1 0 2 2 2 0 Initiation control protein YabA Solute_trans_a PF03619.16 KFR08895.1 - 1.2e-93 313.5 21.4 1.4e-93 313.2 21.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Pkinase PF00069.25 KFR08896.1 - 1.4e-20 73.8 0.0 1.7e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR08896.1 - 1.8e-12 47.1 0.0 2.4e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFR08896.1 - 6.3e-10 38.4 0.1 9.7e-10 37.8 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFR08896.1 - 0.00022 21.2 0.1 0.0014 18.6 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KFR08896.1 - 0.042 12.8 0.1 0.07 12.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KFR08896.1 - 0.096 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IRK_C PF17655.1 KFR08897.1 - 1.2e-76 256.2 0.0 2e-76 255.5 0.0 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFR08897.1 - 1.4e-62 209.7 2.9 1.9e-62 209.2 2.9 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain IRK_N PF08466.10 KFR08897.1 - 0.019 15.1 5.2 0.019 15.1 5.2 1.9 2 0 0 2 2 2 0 Inward rectifier potassium channel N-terminal Ion_trans_2 PF07885.16 KFR08897.1 - 0.11 12.5 12.6 0.18 11.8 11.0 2.1 1 1 1 2 2 2 0 Ion channel DUF92 PF01940.16 KFR08897.1 - 0.13 11.7 0.2 0.23 10.9 0.2 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF92 KASH_CCD PF14662.6 KFR08898.1 - 0.00015 21.6 9.6 0.0019 18.1 9.6 1.9 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Golgin_A5 PF09787.9 KFR08898.1 - 0.0012 18.4 8.1 0.0013 18.3 8.1 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 Tropomyosin PF00261.20 KFR08898.1 - 0.0031 16.9 8.8 0.0043 16.5 8.8 1.3 1 0 0 1 1 1 1 Tropomyosin TSC22 PF01166.18 KFR08898.1 - 0.0038 17.5 5.2 0.042 14.2 0.2 3.1 3 1 1 4 4 3 1 TSC-22/dip/bun family Laminin_II PF06009.12 KFR08898.1 - 0.0038 17.2 5.1 0.047 13.7 4.9 2.0 1 1 1 2 2 2 1 Laminin Domain II GAS PF13851.6 KFR08898.1 - 0.0039 16.6 7.0 0.0054 16.1 7.0 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Uso1_p115_C PF04871.13 KFR08898.1 - 0.012 16.0 7.7 0.017 15.5 7.7 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region TolA_bind_tri PF16331.5 KFR08898.1 - 0.019 15.0 13.3 1 9.5 12.6 2.6 1 1 0 1 1 1 0 TolA binding protein trimerisation Rab5-bind PF09311.11 KFR08898.1 - 0.022 14.2 11.0 0.022 14.1 3.6 1.9 1 1 1 2 2 2 0 Rabaptin-like protein DUF4200 PF13863.6 KFR08898.1 - 0.026 14.9 6.9 0.036 14.5 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) FapA PF03961.13 KFR08898.1 - 0.11 11.1 3.1 0.13 10.8 3.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A JIP_LZII PF16471.5 KFR08898.1 - 0.12 12.6 8.2 1.9 8.7 0.4 2.9 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF1664 PF07889.12 KFR08898.1 - 0.28 11.2 5.1 0.81 9.7 4.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) bZIP_Maf PF03131.17 KFR08898.1 - 0.34 11.4 13.0 0.8 10.3 7.2 2.2 1 1 1 2 2 2 0 bZIP Maf transcription factor Fib_alpha PF08702.10 KFR08898.1 - 0.55 10.4 6.6 0.97 9.6 4.8 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 KFR08898.1 - 0.61 9.6 5.6 0.7 9.4 5.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF745 PF05335.13 KFR08898.1 - 0.71 9.6 7.2 0.79 9.4 5.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF745) YabA PF06156.13 KFR08898.1 - 0.94 10.1 8.5 0.44 11.2 1.8 2.5 1 1 0 2 2 2 0 Initiation control protein YabA DUF16 PF01519.16 KFR08898.1 - 1.1 9.7 7.3 7 7.2 6.0 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF641 PF04859.12 KFR08898.1 - 1.7 9.0 10.0 8.8 6.7 4.9 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Csm1_N PF18504.1 KFR08898.1 - 2 8.8 11.9 2.5 8.5 1.5 2.8 1 1 1 2 2 2 0 Csm1 N-terminal domain GIT_CC PF16559.5 KFR08898.1 - 2.6 8.0 8.7 3.3e+02 1.2 6.9 3.2 1 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor BST2 PF16716.5 KFR08898.1 - 3.6 8.2 13.7 11 6.6 2.3 2.3 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Syntaxin-6_N PF09177.11 KFR08898.1 - 3.6 8.2 8.7 1.5e+02 3.0 0.3 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal CENP-Q PF13094.6 KFR08898.1 - 3.8 7.7 12.9 52 4.0 13.0 2.1 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TMF_DNA_bd PF12329.8 KFR08898.1 - 3.9 7.5 12.1 3.3 7.8 0.3 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding ER_lumen_recept PF00810.18 KFR08899.1 - 3.9e-54 183.5 10.9 7.2e-54 182.6 10.9 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KFR08899.1 - 0.0043 16.8 7.4 0.045 13.5 0.6 3.2 2 1 0 2 2 2 2 PQ loop repeat DUF3810 PF12725.7 KFR08899.1 - 9.3 5.5 13.4 42 3.3 12.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) DEAD PF00270.29 KFR08900.1 - 3.6e-50 170.1 0.0 2.1e-49 167.7 0.0 2.0 1 1 1 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFR08900.1 - 3.6e-31 107.8 0.0 1.1e-30 106.3 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFR08900.1 - 5.9e-05 23.1 0.0 0.00021 21.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF5335 PF17269.2 KFR08900.1 - 0.064 13.1 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) AAA_19 PF13245.6 KFR08900.1 - 0.076 13.3 0.0 8.3 6.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain Ferritin PF00210.24 KFR08900.1 - 0.11 12.4 1.0 0.26 11.2 1.0 1.7 1 1 0 1 1 1 0 Ferritin-like domain Microtub_bind PF13931.6 KFR08900.1 - 0.19 12.1 0.1 0.35 11.3 0.1 1.4 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding Rad51 PF08423.11 KFR08901.1 - 3.7e-109 363.9 0.0 4.8e-109 363.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KFR08901.1 - 5.7e-11 42.4 0.0 7.8e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KFR08901.1 - 2.9e-06 26.8 0.1 6e-06 25.8 0.1 1.6 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 KFR08901.1 - 5.5e-06 26.1 0.0 8.3e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 KFR08901.1 - 2.4e-05 24.9 1.1 4.6e-05 23.9 0.4 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain NRD1_2 PF01995.16 KFR08901.1 - 0.0032 16.8 0.0 0.0062 15.8 0.0 1.4 1 0 0 1 1 1 1 NrpR regulatory domains NRD1 and 2 DnaB_C PF03796.15 KFR08901.1 - 0.036 13.4 0.1 0.13 11.6 0.1 1.8 1 1 1 2 2 2 0 DnaB-like helicase C terminal domain Chibby PF14645.6 KFR08902.1 - 1e-35 122.6 1.9 1.2e-35 122.4 1.9 1.0 1 0 0 1 1 1 1 Chibby family Taxilin PF09728.9 KFR08902.1 - 7e-05 22.2 2.6 8.5e-05 21.9 2.6 1.0 1 0 0 1 1 1 1 Myosin-like coiled-coil protein JIP_LZII PF16471.5 KFR08902.1 - 0.12 12.5 8.7 0.16 12.2 8.7 1.2 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II LapA_dom PF06305.11 KFR08902.1 - 0.13 12.1 1.3 0.14 12.0 0.2 1.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain TSC22 PF01166.18 KFR08902.1 - 1.4 9.3 9.7 0.24 11.7 3.5 2.2 1 1 1 2 2 2 0 TSC-22/dip/bun family DivIC PF04977.15 KFR08902.1 - 3.1 7.6 6.7 1.6 8.6 3.2 1.9 1 1 1 2 2 2 0 Septum formation initiator Josephin PF02099.17 KFR08903.1 - 5.4e-29 101.4 0.5 1.3e-27 96.9 0.5 2.0 1 1 0 1 1 1 1 Josephin AhpC-TSA PF00578.21 KFR08903.1 - 0.12 12.3 0.1 0.72 9.8 0.0 2.1 2 0 0 2 2 2 0 AhpC/TSA family GTP_EFTU PF00009.27 KFR08904.1 - 1e-23 83.9 0.0 1.7e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KFR08904.1 - 6.1e-07 29.7 0.7 2.2e-06 27.9 0.1 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KFR08904.1 - 0.00041 20.6 0.4 0.0022 18.3 0.2 2.3 2 1 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KFR08904.1 - 0.0013 18.7 0.1 0.0041 17.2 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KFR08904.1 - 0.0019 18.0 0.0 3.2 7.5 0.0 3.6 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KFR08904.1 - 0.028 14.3 0.1 4.4 7.2 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 KFR08904.1 - 0.11 12.6 0.2 0.69 10.0 0.1 2.2 1 1 1 2 2 2 0 Dynamin family Arf PF00025.21 KFR08904.1 - 0.16 11.4 0.1 15 5.0 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family Sad1_UNC PF07738.13 KFR08905.1 - 1.2e-44 151.6 0.0 1.7e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Sun2_CC2 PF18580.1 KFR08905.1 - 1.9e-23 82.4 4.1 1.9e-23 82.4 4.1 2.8 2 0 0 2 2 2 1 SUN2 coiled coil domain 2 DUF1640 PF07798.11 KFR08905.1 - 0.0049 16.9 0.3 0.016 15.3 0.0 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1640) ZapB PF06005.12 KFR08905.1 - 0.017 15.5 0.6 0.017 15.5 0.6 3.0 4 0 0 4 4 3 0 Cell division protein ZapB FAM184 PF15665.5 KFR08905.1 - 0.034 13.9 4.2 0.064 13.0 4.2 1.4 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B FlaC_arch PF05377.11 KFR08905.1 - 0.051 14.0 0.2 0.2 12.1 0.1 2.0 2 0 0 2 2 1 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.21 KFR08905.1 - 0.067 13.3 2.4 0.3 11.2 0.3 2.7 2 1 0 2 2 2 0 bZIP transcription factor Gp58 PF07902.11 KFR08905.1 - 0.12 10.6 0.2 0.18 10.1 0.2 1.1 1 0 0 1 1 1 0 gp58-like protein DUF4407 PF14362.6 KFR08905.1 - 0.13 11.6 4.0 0.38 10.0 4.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4618 PF15397.6 KFR08905.1 - 0.16 11.4 1.6 0.31 10.4 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Apolipoprotein PF01442.18 KFR08905.1 - 0.2 11.5 13.8 0.45 10.4 13.8 1.6 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain ThiD2 PF17792.1 KFR08905.1 - 0.24 11.9 2.0 0.73 10.3 0.1 2.4 1 1 1 3 3 3 0 ThiD2 family DUF1664 PF07889.12 KFR08905.1 - 0.29 11.2 0.9 1.2 9.1 0.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 KFR08905.1 - 0.31 11.5 6.2 0.53 10.7 6.2 1.3 1 0 0 1 1 1 0 Fez1 Spc7 PF08317.11 KFR08905.1 - 0.36 9.7 2.8 0.67 8.8 2.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein YlqD PF11068.8 KFR08905.1 - 0.97 9.8 4.2 2.4 8.6 4.2 1.6 1 0 0 1 1 1 0 YlqD protein Mod_r PF07200.13 KFR08905.1 - 2.9 8.0 5.7 1.6 8.8 3.0 1.9 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein WXG100 PF06013.12 KFR08905.1 - 4.5 7.6 6.4 18 5.6 4.9 2.7 1 1 2 3 3 3 0 Proteins of 100 residues with WXG DivIC PF04977.15 KFR08905.1 - 9.5 6.1 7.2 6.1 6.7 0.2 3.5 3 0 0 3 3 3 0 Septum formation initiator Fam20C PF06702.12 KFR08906.1 - 1.2e-102 342.4 0.0 1.6e-102 341.9 0.0 1.2 1 0 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 FAM198 PF15051.6 KFR08906.1 - 0.038 12.9 0.0 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 FAM198 protein Dynein_light PF01221.18 KFR08907.1 - 7.4e-28 96.7 0.2 9.3e-28 96.4 0.2 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 DUF3109 PF11307.8 KFR08907.1 - 0.018 14.8 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3109) GARS_A PF01071.19 KFR08907.1 - 0.047 13.4 0.0 0.054 13.3 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Pentaxin PF00354.17 KFR08908.1 - 3.3e-34 118.3 0.0 4.7e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 Pentaxin family CBX7_C PF17218.3 KFR08908.1 - 2.4e-14 52.8 1.2 4.9e-14 51.8 1.2 1.6 1 0 0 1 1 1 1 CBX family C-terminal motif Laminin_G_3 PF13385.6 KFR08908.1 - 2.8e-12 47.0 0.0 4.7e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Chromo PF00385.24 KFR08909.1 - 1.5e-11 44.0 0.7 2.7e-11 43.2 0.7 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CBX7_C PF17218.3 KFR08909.1 - 5.3e-11 42.0 2.1 1e-10 41.1 2.1 1.4 1 0 0 1 1 1 1 CBX family C-terminal motif PDGF PF00341.17 KFR08910.1 - 8.7e-25 86.8 12.6 1.6e-24 86.0 12.6 1.4 1 0 0 1 1 1 1 PDGF/VEGF domain PDGF_N PF04692.13 KFR08910.1 - 9.4e-13 48.8 0.3 9.4e-13 48.8 0.3 2.0 2 0 0 2 2 2 1 Platelet-derived growth factor, N terminal region Ribosomal_L3 PF00297.22 KFR08911.1 - 1e-190 633.4 11.4 1.2e-190 633.3 11.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 RTX PF02382.15 KFR08911.1 - 0.021 14.5 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in RTX protein DUF3903 PF13043.6 KFR08911.1 - 0.2 11.4 0.7 0.67 9.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3903) Glyco_transf_17 PF04724.13 KFR08913.1 - 1.5e-29 103.2 2.2 6.4e-25 87.9 0.0 3.3 4 0 0 4 4 4 3 Glycosyltransferase family 17 EGF_2 PF07974.13 KFR08913.1 - 0.26 11.7 0.8 0.69 10.3 0.8 1.7 1 0 0 1 1 1 0 EGF-like domain Mab-21 PF03281.14 KFR08914.1 - 7.5e-16 58.3 0.0 4.2e-15 55.8 0.0 2.0 1 1 0 1 1 1 1 Mab-21 protein bZIP_1 PF00170.21 KFR08915.1 - 6.2e-16 58.3 14.8 6.2e-16 58.3 14.8 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KFR08915.1 - 3.3e-07 30.3 12.4 6.5e-07 29.3 12.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper ZapB PF06005.12 KFR08915.1 - 0.032 14.7 4.9 0.032 14.7 4.9 2.2 1 1 1 2 2 2 0 Cell division protein ZapB DUF3450 PF11932.8 KFR08915.1 - 0.047 13.0 8.1 0.085 12.1 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Atg14 PF10186.9 KFR08915.1 - 0.077 12.1 12.2 0.14 11.2 12.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Syntaxin-6_N PF09177.11 KFR08915.1 - 0.23 12.1 3.6 0.39 11.3 2.8 1.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Laminin_II PF06009.12 KFR08915.1 - 0.23 11.5 6.3 0.44 10.6 6.3 1.4 1 0 0 1 1 1 0 Laminin Domain II Fez1 PF06818.15 KFR08915.1 - 0.25 11.7 11.8 0.42 11.0 11.8 1.3 1 0 0 1 1 1 0 Fez1 DUF2009 PF09418.10 KFR08915.1 - 0.43 9.6 4.1 0.59 9.1 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) SOBP PF15279.6 KFR08915.1 - 0.47 11.0 6.3 0.8 10.3 6.3 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein UPF0242 PF06785.11 KFR08915.1 - 0.63 10.1 8.8 0.95 9.5 8.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Baculo_F PF12259.8 KFR08915.1 - 0.69 8.4 5.8 1 7.8 5.8 1.1 1 0 0 1 1 1 0 Baculovirus F protein bZIP_Maf PF03131.17 KFR08915.1 - 0.75 10.4 10.2 1.3 9.6 10.2 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF724 PF05266.14 KFR08915.1 - 0.97 9.2 12.2 2 8.2 12.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) AAA_13 PF13166.6 KFR08915.1 - 1.5 7.4 11.9 1.9 7.0 11.9 1.1 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 KFR08915.1 - 2 7.7 8.9 2.9 7.2 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAUS6_N PF14661.6 KFR08915.1 - 2.5 7.6 8.9 3.9 7.0 8.9 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus OmpH PF03938.14 KFR08915.1 - 3.5 8.0 15.1 5.5 7.3 15.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AROS PF15684.5 KFR08916.1 - 7.6e-34 117.1 2.5 8.6e-34 116.9 2.5 1.1 1 0 0 1 1 1 1 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 Ion_trans PF00520.31 KFR08917.1 - 8.7e-255 840.6 82.9 1.2e-77 260.5 16.4 4.1 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 KFR08917.1 - 1e-16 60.7 86.6 3.3e-09 35.9 3.2 9.8 6 3 3 9 9 9 7 Polycystin cation channel TMEM208_SND2 PF05620.11 KFR08917.1 - 0.032 14.0 1.0 2.5 7.9 0.0 3.3 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 DUF3043 PF11241.8 KFR08917.1 - 1 9.4 10.1 2.9 7.9 0.0 4.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3043) SieB PF14163.6 KFR08917.1 - 1.6 8.2 11.7 1.5 8.3 0.1 3.8 3 0 0 3 3 3 0 Super-infection exclusion protein B FAM83 PF07894.12 KFR08918.1 - 4.7e-109 364.2 0.0 6.7e-109 363.7 0.0 1.2 1 0 0 1 1 1 1 FAM83 A-H PLDc_2 PF13091.6 KFR08918.1 - 1.5e-07 31.4 0.0 2.7e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 PLD-like domain Clathrin_bdg PF15045.6 KFR08918.1 - 0.098 12.7 0.3 9.6 6.3 0.0 2.6 2 0 0 2 2 2 0 Clathrin-binding box of Aftiphilin, vesicle trafficking DUF1465 PF07323.12 KFR08918.1 - 0.35 10.7 4.1 3.5 7.5 3.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) TNRC6-PABC_bdg PF16608.5 KFR08919.1 - 1e-105 353.6 26.8 1e-105 353.6 26.8 8.5 4 2 5 10 10 10 1 TNRC6-PABC binding domain SUIM_assoc PF16619.5 KFR08919.1 - 5.4e-07 29.6 0.0 0.18 11.9 0.8 4.8 3 1 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 RRM_occluded PF16842.5 KFR08919.1 - 0.00013 21.7 0.0 0.0003 20.6 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_1 PF00076.22 KFR08919.1 - 0.00075 19.3 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lyase_1 PF00206.20 KFR08920.1 - 1.8e-26 93.3 0.0 2.6e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KFR08920.1 - 3.5e-18 65.9 0.0 1e-17 64.4 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF1331 PF07048.11 KFR08920.1 - 0.06 13.0 0.2 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) DUF4089 PF13318.6 KFR08920.1 - 0.073 13.5 0.0 0.21 12.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4089) RabGAP-TBC PF00566.18 KFR08921.1 - 1e-50 172.4 1.5 1.5e-50 171.9 1.5 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RUN PF02759.19 KFR08921.1 - 2.5e-31 108.4 0.1 6.7e-31 107.0 0.1 1.8 1 0 0 1 1 1 1 RUN domain SH3_1 PF00018.28 KFR08921.1 - 5.8e-12 45.0 0.1 1.3e-11 43.9 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFR08921.1 - 7e-10 38.6 0.0 1.6e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFR08921.1 - 1.3e-09 37.6 0.0 2.7e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain RPEL PF02755.15 KFR08922.1 - 3.4e-24 83.8 8.7 2.8e-08 33.2 0.1 3.9 3 0 0 3 3 3 3 RPEL repeat SAP PF02037.27 KFR08922.1 - 6.3e-12 45.0 0.5 1.5e-11 43.7 0.5 1.7 1 0 0 1 1 1 1 SAP domain DUF722 PF05263.11 KFR08922.1 - 0.051 13.8 0.5 0.11 12.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF722) MPS2 PF17060.5 KFR08922.1 - 0.27 10.5 3.1 0.15 11.3 0.4 1.9 2 0 0 2 2 2 0 Monopolar spindle protein 2 Mito_carr PF00153.27 KFR08923.1 - 2e-53 178.3 1.0 1.7e-22 79.1 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein ECF_trnsprt PF12822.7 KFR08923.1 - 0.17 11.9 1.8 1.1 9.3 0.5 2.4 2 1 0 2 2 2 0 ECF transporter, substrate-specific component TPR_1 PF00515.28 KFR08924.1 - 1.3e-12 47.0 1.5 3.2e-05 23.6 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat STI1 PF17830.1 KFR08924.1 - 3e-12 46.3 3.3 3e-12 46.3 3.3 2.6 3 0 0 3 3 2 1 STI1 domain TPR_2 PF07719.17 KFR08924.1 - 4e-11 42.1 7.8 0.0042 17.1 1.3 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFR08924.1 - 6.7e-09 35.3 0.2 0.00043 19.9 0.0 3.3 1 1 2 3 3 3 2 TPR repeat TPR_16 PF13432.6 KFR08924.1 - 1.2e-06 29.0 0.1 0.00022 21.8 0.1 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFR08924.1 - 1.4e-06 28.2 0.2 0.028 14.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFR08924.1 - 2.6e-06 27.5 1.0 7.6e-06 26.0 0.8 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFR08924.1 - 6.5e-06 26.5 5.3 0.025 15.4 0.0 4.0 2 1 2 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFR08924.1 - 1.1e-05 25.3 0.5 0.028 14.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFR08924.1 - 0.0071 16.8 1.0 0.54 10.8 0.0 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat Rrn6 PF10214.9 KFR08924.1 - 0.01 14.4 0.8 0.012 14.1 0.8 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor TPR_6 PF13174.6 KFR08924.1 - 0.014 16.0 0.3 77 4.3 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFR08924.1 - 0.02 15.2 3.1 0.13 12.6 0.2 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFR08924.1 - 0.034 14.2 0.2 13 6.1 0.2 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat RhoGEF67_u2 PF16614.5 KFR08924.1 - 0.84 9.7 3.6 3.3 7.8 2.1 2.6 3 0 0 3 3 3 0 Unstructured region two on RhoGEF 6 and 7 baeRF_family3 PF18845.1 KFR08924.1 - 1.2 9.4 7.8 2.3 8.4 1.5 3.0 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 3 D5_N PF08706.11 KFR08924.1 - 7.6 6.8 9.5 53 4.0 9.5 2.2 1 1 0 1 1 1 0 D5 N terminal like DUF2203 PF09969.9 KFR08924.1 - 9.1 7.0 9.3 5.7 7.7 6.5 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Peptidase_M24 PF00557.24 KFR08925.1 - 1.8e-57 194.4 0.0 2.4e-57 194.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KFR08925.1 - 4.5e-37 126.5 0.0 8.2e-37 125.7 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain zf-rbx1 PF12678.7 KFR08926.1 - 6.6e-26 90.4 12.9 7.8e-26 90.1 12.9 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFR08926.1 - 1.1e-15 57.5 10.7 1.3e-15 57.2 10.7 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KFR08926.1 - 5.4e-07 29.8 14.9 2.9e-05 24.3 14.9 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFR08926.1 - 2.3e-05 24.1 3.2 2.3e-05 24.1 3.2 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFR08926.1 - 0.00038 20.3 12.2 0.0083 16.0 12.2 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFR08926.1 - 0.031 14.1 11.4 0.17 11.8 5.2 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KFR08926.1 - 0.039 13.6 5.3 0.039 13.6 5.3 2.2 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KFR08926.1 - 0.14 12.4 9.4 0.87 9.8 9.6 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_11 PF17123.5 KFR08926.1 - 0.14 11.9 16.6 17 5.2 16.6 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 KFR08926.1 - 0.17 11.9 8.3 0.71 9.9 8.3 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFR08926.1 - 3.1 8.0 9.4 0.39 10.9 0.7 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KFR08926.1 - 3.9 7.5 13.6 40 4.3 13.6 2.5 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING-like PF08746.11 KFR08926.1 - 4.2 7.7 13.0 52 4.3 13.0 2.3 1 1 0 1 1 1 0 RING-like domain MBT PF02820.18 KFR08928.1 - 8.6e-99 324.0 4.8 1.2e-27 96.0 0.2 4.4 4 0 0 4 4 4 4 mbt repeat RanGAP1_C PF07834.11 KFR08929.1 - 2.1e-66 223.0 0.8 2.1e-66 223.0 0.8 1.5 2 0 0 2 2 1 1 RanGAP1 C-terminal domain LRR_6 PF13516.6 KFR08929.1 - 2.6e-16 58.2 8.8 0.16 12.1 0.0 9.1 9 0 0 9 9 9 4 Leucine Rich repeat LRR_1 PF00560.33 KFR08929.1 - 3.6e-06 26.8 0.6 5.9 7.8 0.1 5.8 6 0 0 6 6 5 1 Leucine Rich Repeat LRR_4 PF12799.7 KFR08929.1 - 3.1e-05 24.3 3.5 8.2 7.0 0.0 5.2 4 2 2 6 6 6 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFR08929.1 - 6.3e-05 22.7 0.6 5.8 6.8 0.4 5.0 4 1 0 4 4 4 1 Leucine rich repeat CPSF100_C PF13299.6 KFR08929.1 - 0.0076 16.4 2.4 0.015 15.5 2.4 1.4 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Nop14 PF04147.12 KFR08929.1 - 0.015 13.6 5.3 0.019 13.2 5.3 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KFR08929.1 - 0.081 12.3 5.8 0.13 11.6 5.8 1.3 1 0 0 1 1 1 0 BUD22 MCR_beta_N PF02783.15 KFR08929.1 - 0.083 12.5 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain PI3K_1B_p101 PF10486.9 KFR08929.1 - 0.11 10.3 2.3 0.16 9.7 2.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit THOC2_N PF16134.5 KFR08929.1 - 0.21 10.1 7.3 0.92 8.1 2.7 2.2 2 0 0 2 2 2 0 THO complex subunit 2 N-terminus DUF1840 PF08895.11 KFR08929.1 - 0.64 10.4 3.6 4.9 7.5 1.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Nse4-Nse3_bdg PF15412.6 KFR08929.1 - 1.1 9.5 0.0 1.1 9.5 0.0 2.5 2 1 0 2 2 1 0 Binding domain of Nse4/EID3 to Nse3-MAGE NOA36 PF06524.12 KFR08929.1 - 1.3 8.3 10.1 2 7.7 10.1 1.2 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 KFR08929.1 - 2 6.6 9.0 3.2 6.0 9.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 KFR08929.1 - 2 8.3 12.3 5.2 6.9 12.3 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region Paf1 PF03985.13 KFR08929.1 - 3.2 6.6 12.7 5.4 5.9 12.7 1.3 1 0 0 1 1 1 0 Paf1 Ribosomal_60s PF00428.19 KFR08929.1 - 3.9 8.1 13.3 0.38 11.4 7.6 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein RNA_pol_3_Rpc31 PF11705.8 KFR08929.1 - 8.6 6.5 15.6 11 6.2 13.5 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 zf-CCCH PF00642.24 KFR08930.1 - 7.3e-13 48.1 27.3 2.1e-05 24.3 2.4 4.7 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TPR_1 PF00515.28 KFR08930.1 - 2.5e-08 33.4 0.9 3.6e-06 26.5 0.6 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFR08930.1 - 6.3e-05 23.2 1.2 0.00053 20.2 0.5 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFR08930.1 - 8.4e-05 22.4 2.6 0.00058 19.8 0.5 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFR08930.1 - 0.00074 19.5 1.0 0.0042 17.2 0.5 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-C2H2_2 PF12756.7 KFR08930.1 - 0.0019 18.5 0.8 0.0082 16.5 0.8 2.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-CCCH_4 PF18044.1 KFR08930.1 - 0.021 14.6 0.9 0.021 14.6 0.9 4.6 4 0 0 4 4 4 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFR08930.1 - 0.022 14.8 0.8 0.022 14.8 0.8 4.7 4 0 0 4 4 4 0 Zinc finger domain TPR_11 PF13414.6 KFR08930.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 TPR repeat zf-C2H2_jaz PF12171.8 KFR08930.1 - 0.59 10.5 12.9 0.066 13.5 7.5 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-CCCH_2 PF14608.6 KFR08930.1 - 6.6 7.4 22.5 7 7.3 1.2 4.8 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger bZIP_2 PF07716.15 KFR08931.1 - 9.6e-16 57.6 11.9 9.6e-16 57.6 11.9 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KFR08931.1 - 3.2e-06 27.1 7.9 6.1e-06 26.2 7.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor Cnn_1N PF07989.11 KFR08931.1 - 0.011 15.8 0.5 0.026 14.7 0.5 1.7 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 bZIP_Maf PF03131.17 KFR08931.1 - 0.037 14.5 5.4 0.087 13.3 5.4 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor BTG PF07742.12 KFR08932.1 - 1.1e-37 128.4 0.0 1.6e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 BTG family PAM2 PF07145.15 KFR08932.1 - 7.3e-13 47.2 1.6 1.8e-05 24.1 0.1 3.6 3 0 0 3 3 3 2 Ataxin-2 C-terminal region PHF5 PF03660.14 KFR08933.1 - 2.1e-39 133.9 14.1 2.3e-39 133.8 14.1 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 KFR08933.1 - 0.087 10.7 7.8 0.088 10.7 7.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Aconitase PF00330.20 KFR08934.1 - 1.3e-148 495.9 0.0 1.6e-148 495.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KFR08934.1 - 4.6e-46 156.4 0.0 9.1e-46 155.4 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain RNA_pol_Rbc25 PF08292.12 KFR08935.1 - 1e-43 148.7 0.1 1.6e-43 148.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KFR08935.1 - 4.3e-20 71.8 0.1 9.1e-20 70.8 0.0 1.6 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 CSD PF00313.22 KFR08936.1 - 1.7e-13 50.2 0.1 2.2e-13 49.8 0.1 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KFR08936.1 - 0.0026 17.4 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease B OB domain PMM PF03332.13 KFR08937.1 - 3.3e-96 321.3 0.2 3.7e-96 321.2 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Peptidase_C97 PF05903.14 KFR08938.1 - 4.2e-44 150.0 0.0 4.8e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain Ku_N PF03731.15 KFR08939.1 - 1.7e-71 240.5 0.0 3.7e-71 239.4 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.16 KFR08939.1 - 3e-57 193.6 0.3 4.9e-57 192.9 0.3 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain SAP PF02037.27 KFR08939.1 - 2.4e-11 43.1 0.0 4.7e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 SAP domain Ku_C PF03730.14 KFR08939.1 - 5.8e-11 42.9 0.5 2.5e-07 31.3 0.1 3.0 2 0 0 2 2 2 2 Ku70/Ku80 C-terminal arm TSC22 PF01166.18 KFR08939.1 - 0.14 12.5 1.1 0.34 11.2 0.0 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family Ribosomal_L7Ae PF01248.26 KFR08940.1 - 5.3e-26 90.2 0.1 6.6e-26 89.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KFR08940.1 - 0.00031 20.8 0.1 0.00035 20.6 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KFR08940.1 - 0.0069 16.2 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 PELOTA RNA binding domain DUF2111 PF09884.9 KFR08941.1 - 0.21 11.7 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2111) TisB_toxin PF13939.6 KFR08941.1 - 3.9 7.3 7.1 7.7 6.4 1.1 3.1 2 0 0 2 2 2 0 Toxin TisB, type I toxin-antitoxin system ERK-JNK_inhib PF15002.6 KFR08942.1 - 3.5e-54 183.5 0.0 4e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 ERK and JNK pathways, inhibitor HLH PF00010.26 KFR08943.1 - 3.2e-17 62.2 0.6 8.4e-17 60.9 0.6 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain BaffR-Tall_bind PF09256.10 KFR08944.1 - 1.4e-05 24.8 2.4 3.4e-05 23.5 2.4 1.7 1 0 0 1 1 1 1 BAFF-R, TALL-1 binding TMEM154 PF15102.6 KFR08944.1 - 0.079 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family CENP-M PF11111.8 KFR08945.1 - 1.7e-70 235.7 0.0 1.9e-70 235.6 0.0 1.0 1 0 0 1 1 1 1 Centromere protein M (CENP-M) Septin PF00735.18 KFR08946.1 - 6.3e-115 383.3 1.1 8.3e-115 382.9 1.1 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFR08946.1 - 4.7e-08 33.1 0.0 1.1e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFR08946.1 - 6.5e-06 26.2 4.2 2.9e-05 24.1 1.4 2.5 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KFR08946.1 - 3.4e-05 23.5 0.6 0.018 14.6 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KFR08946.1 - 5.1e-05 22.7 0.1 9.3e-05 21.8 0.1 1.5 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KFR08946.1 - 0.00032 20.8 7.8 0.1 12.7 0.8 3.6 2 2 1 3 3 3 2 Dynamin family AAA_16 PF13191.6 KFR08946.1 - 0.0011 19.3 0.0 0.002 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 KFR08946.1 - 0.0017 18.5 0.2 0.0038 17.4 0.2 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KFR08946.1 - 0.0019 18.8 0.3 0.0063 17.0 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 KFR08946.1 - 0.0022 18.3 0.0 0.0057 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 KFR08946.1 - 0.0028 17.0 0.1 0.0055 16.1 0.1 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Ras PF00071.22 KFR08946.1 - 0.0059 16.2 0.1 0.015 14.9 0.0 1.8 2 0 0 2 2 2 1 Ras family AAA_24 PF13479.6 KFR08946.1 - 0.0073 16.1 0.1 0.26 11.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KFR08946.1 - 0.011 14.9 0.2 0.011 14.9 0.2 1.5 2 0 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.6 KFR08946.1 - 0.021 14.6 0.1 0.041 13.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 KFR08946.1 - 0.031 13.4 3.4 0.089 11.9 3.4 1.8 1 1 0 1 1 1 0 G-protein alpha subunit Sigma54_activat PF00158.26 KFR08946.1 - 0.042 13.6 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.13 KFR08946.1 - 0.052 12.7 0.0 0.097 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 KFR08946.1 - 0.055 13.2 0.1 1.5 8.6 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation IIGP PF05049.13 KFR08946.1 - 0.055 12.5 0.7 0.11 11.6 0.1 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_32 PF13654.6 KFR08946.1 - 0.069 11.9 0.9 0.088 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 KFR08946.1 - 0.07 12.7 0.1 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 KFR08946.1 - 0.075 12.5 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region GRAM PF02893.20 KFR08947.1 - 3.3e-14 52.8 0.0 4.2e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 GRAM domain Melibiase_2 PF16499.5 KFR08948.1 - 1.9e-155 516.2 0.2 2.1e-155 516.0 0.2 1.0 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase PF02065.18 KFR08948.1 - 2.2e-05 23.6 0.0 3.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Melibiase Complex1_LYR PF05347.15 KFR08949.1 - 2.1e-08 34.1 0.0 3.2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF4252 PF14060.6 KFR08949.1 - 0.038 13.9 0.1 0.045 13.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) p450 PF00067.22 KFR08950.1 - 1.9e-130 435.7 0.1 2.2e-130 435.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1229 PF06797.11 KFR08950.1 - 0.084 13.1 0.0 0.24 11.6 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1229) zf-HC5HC2H PF13771.6 KFR08951.1 - 7.1e-09 35.8 5.9 2.1e-08 34.3 5.9 1.9 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFR08951.1 - 3.7e-08 33.5 1.4 1e-07 32.0 1.4 1.7 1 0 0 1 1 1 1 PHD-zinc-finger like domain SH2 PF00017.24 KFR08952.1 - 3e-06 27.2 0.0 3.7e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 SH2 domain Abhydrolase_1 PF00561.20 KFR08953.1 - 6.7e-21 75.1 0.6 3.5e-20 72.7 0.6 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFR08953.1 - 3.7e-17 63.7 0.4 5.3e-17 63.2 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFR08953.1 - 5.3e-12 45.5 0.0 1.2e-11 44.4 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KFR08953.1 - 0.00071 19.7 1.0 0.0077 16.4 0.1 2.3 2 1 0 2 2 2 1 Thioesterase domain Lipase_3 PF01764.25 KFR08953.1 - 0.022 14.6 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 KFR08953.1 - 0.036 13.8 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_5 PF12695.7 KFR08953.1 - 0.11 12.2 0.0 0.35 10.6 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Esterase PF00756.20 KFR08953.1 - 0.17 11.5 0.1 0.29 10.7 0.1 1.6 1 1 0 1 1 1 0 Putative esterase CitT PF12431.8 KFR08953.1 - 0.24 11.8 0.6 1.6 9.2 0.1 2.4 3 0 0 3 3 3 0 Transcriptional regulator RRP7 PF12923.7 KFR08954.1 - 3.6e-35 120.7 10.2 5.4e-35 120.1 10.2 1.3 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_1 PF00076.22 KFR08954.1 - 9.6e-07 28.5 0.0 0.00018 21.3 0.0 2.6 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5093 PF17011.5 KFR08954.1 - 0.02 15.1 0.6 0.044 14.1 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5093) RRM_Rrp7 PF17799.1 KFR08954.1 - 0.12 12.2 0.0 0.44 10.3 0.0 1.9 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain Trans_reg_C PF00486.28 KFR08954.1 - 0.18 11.9 1.9 0.4 10.8 0.7 2.0 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal MIEAP PF16026.5 KFR08955.1 - 0.0033 17.7 1.5 0.0045 17.2 1.5 1.2 1 0 0 1 1 1 1 Mitochondria-eating protein Globin PF00042.22 KFR08956.1 - 1.8e-30 105.7 0.1 3.1e-30 105.0 0.0 1.4 2 0 0 2 2 2 1 Globin BEN PF10523.9 KFR08956.1 - 0.025 14.8 0.1 0.062 13.5 0.0 1.7 2 0 0 2 2 2 0 BEN domain IL12 PF03039.14 KFR08956.1 - 0.033 13.5 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 Interleukin-12 alpha subunit Sulfotransfer_3 PF13469.6 KFR08956.1 - 0.16 12.3 0.0 0.2 12.0 0.0 1.3 1 1 0 1 1 1 0 Sulfotransferase family LUC7 PF03194.15 KFR08957.1 - 4.4e-70 236.2 13.6 4.4e-70 236.2 13.6 2.5 1 1 1 2 2 2 1 LUC7 N_terminus UBN_AB PF14075.6 KFR08959.1 - 6.3e-82 274.4 4.1 6.3e-82 274.4 4.1 2.4 2 1 0 2 2 2 1 Ubinuclein conserved middle domain HUN PF08729.10 KFR08959.1 - 1.7e-19 69.5 0.4 4e-19 68.3 0.4 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain TPR_19 PF14559.6 KFR08960.1 - 5e-17 62.2 10.9 2.4e-05 24.8 0.5 5.7 5 1 1 6 6 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KFR08960.1 - 2.4e-10 40.5 23.6 0.00062 19.9 0.4 5.4 4 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KFR08960.1 - 2e-08 33.7 30.2 0.028 14.5 0.3 8.5 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFR08960.1 - 2.1e-08 34.3 6.6 0.98 10.4 0.1 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFR08960.1 - 3.4e-08 33.1 8.4 0.0024 18.0 0.0 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFR08960.1 - 3e-06 27.3 2.2 0.013 15.6 0.3 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFR08960.1 - 2.8e-05 24.2 6.1 0.0057 17.0 0.0 5.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFR08960.1 - 3.1e-05 24.5 7.7 0.15 12.7 0.4 5.5 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFR08960.1 - 3.7e-05 24.1 12.7 0.059 14.0 0.0 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFR08960.1 - 5.3e-05 23.0 10.3 1.2 9.3 0.3 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFR08960.1 - 0.00019 21.1 21.5 0.0041 16.9 0.1 6.2 7 0 0 7 7 6 3 Tetratricopeptide repeat PPR PF01535.20 KFR08960.1 - 0.00073 19.6 0.3 5.3 7.5 0.0 4.6 4 0 0 4 4 4 1 PPR repeat TPR_4 PF07721.14 KFR08960.1 - 0.00094 19.6 0.0 24 5.9 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFR08960.1 - 0.0014 18.9 16.4 1 9.7 0.0 6.4 6 2 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFR08960.1 - 0.0057 16.3 0.1 0.065 12.9 0.0 2.7 2 0 0 2 2 2 1 TPR repeat PyocinActivator PF11112.8 KFR08960.1 - 0.019 15.1 0.1 0.049 13.8 0.1 1.7 1 0 0 1 1 1 0 Pyocin activator protein PrtN PPR_2 PF13041.6 KFR08960.1 - 0.021 15.0 0.6 4.8 7.5 0.1 3.5 3 1 1 4 4 4 0 PPR repeat family Fis1_TPR_C PF14853.6 KFR08960.1 - 0.54 10.4 5.1 6 7.0 0.2 3.9 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KFR08960.1 - 0.67 9.9 14.8 14 5.7 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Guanylate_cyc PF00211.20 KFR08961.1 - 9.2e-67 224.2 0.0 2.3e-66 222.9 0.0 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 KFR08961.1 - 5.3e-36 124.2 0.1 1.6e-35 122.7 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR08961.1 - 3.3e-29 102.1 0.1 7.6e-29 100.9 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain ANF_receptor PF01094.28 KFR08961.1 - 2.6e-08 33.4 0.0 5e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 Receptor family ligand binding region Peripla_BP_6 PF13458.6 KFR08961.1 - 0.22 11.1 0.0 0.37 10.4 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Phospholip_B PF04916.13 KFR08962.1 - 6.3e-181 602.6 3.5 7.6e-181 602.3 3.5 1.1 1 0 0 1 1 1 1 Phospholipase B Nucleo_LEF-12 PF06256.11 KFR08962.1 - 0.0016 18.3 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 Nucleopolyhedrovirus LEF-12 protein NMDAR2_C PF10565.9 KFR08963.1 - 2.1e-227 757.2 12.8 2.5e-227 756.9 12.8 1.1 1 0 0 1 1 1 1 N-methyl D-aspartate receptor 2B3 C-terminus Lig_chan PF00060.26 KFR08963.1 - 1.3e-33 116.0 0.1 2.1e-33 115.3 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFR08963.1 - 7.9e-31 106.6 0.1 5.5e-30 103.9 0.1 2.1 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFR08963.1 - 1.1e-24 87.1 0.0 1.8e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 KFR08963.1 - 9.2e-11 41.4 0.0 8.3e-09 35.0 0.0 2.3 1 1 0 1 1 1 1 Receptor family ligand binding region DUF4013 PF13197.6 KFR08963.1 - 3.2 7.5 6.9 3.5 7.4 4.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4013) PMP22_Claudin PF00822.20 KFR08964.1 - 8.1e-46 155.9 18.8 9.3e-46 155.7 18.8 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFR08964.1 - 0.00018 21.4 15.2 0.00018 21.4 15.2 3.0 1 1 2 3 3 3 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.11 KFR08964.1 - 0.00074 19.4 13.2 0.00074 19.4 13.2 1.9 1 1 1 2 2 2 1 Amastin surface glycoprotein DUF4064 PF13273.6 KFR08964.1 - 0.00085 19.6 19.6 0.0032 17.7 9.2 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF4064) SUR7 PF06687.12 KFR08964.1 - 0.0013 18.4 13.7 0.0013 18.4 13.7 2.4 1 1 1 2 2 2 1 SUR7/PalI family DUF1422 PF07226.11 KFR08964.1 - 0.004 17.2 4.0 0.004 17.2 4.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1422) 7TMR-DISM_7TM PF07695.11 KFR08964.1 - 0.061 13.2 24.5 0.85 9.5 22.1 2.4 1 1 1 2 2 2 0 7TM diverse intracellular signalling Claudin_3 PF06653.11 KFR08964.1 - 0.38 10.7 21.3 0.99 9.3 21.3 1.7 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DUF998 PF06197.13 KFR08964.1 - 0.47 10.0 12.9 0.025 14.2 3.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF998) PalH PF08733.10 KFR08964.1 - 7.4 5.5 17.5 0.43 9.5 8.2 2.0 2 0 0 2 2 2 0 PalH/RIM21 GSG-1 PF07803.11 KFR08965.1 - 3.8e-50 168.7 0.0 6.6e-50 167.9 0.0 1.4 1 0 0 1 1 1 1 GSG1-like protein PMP22_Claudin PF00822.20 KFR08965.1 - 1.2e-07 31.7 2.3 1.2e-07 31.7 2.3 2.3 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFR08965.1 - 4.5e-07 29.8 2.4 8.1e-07 29.0 2.4 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 KFR08965.1 - 0.023 14.6 6.3 0.3 11.0 4.5 2.2 2 0 0 2 2 2 0 Tight junction protein, Claudin-like Clc-like PF07062.12 KFR08965.1 - 0.81 9.1 0.0 0.81 9.1 0.0 2.8 3 1 0 3 3 3 0 Clc-like PQQ_2 PF13360.6 KFR08966.1 - 5e-07 29.5 0.1 0.0054 16.3 0.0 2.4 2 0 0 2 2 2 2 PQQ-like domain VCBS PF13517.6 KFR08966.1 - 4.5e-06 27.2 0.1 0.23 12.1 0.0 3.4 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KFR08966.1 - 0.00012 22.1 6.0 0.047 13.8 0.3 3.0 2 1 0 2 2 2 2 FG-GAP repeat DUF1409 PF07197.12 KFR08967.1 - 0.0067 16.3 0.1 0.016 15.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1409) RPW8 PF05659.11 KFR08967.1 - 0.062 13.0 0.4 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 I_LWEQ PF01608.17 KFR08967.1 - 0.079 13.2 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 I/LWEQ domain HxlR PF01638.17 KFR08967.1 - 0.12 12.3 1.9 0.22 11.4 0.5 2.0 2 0 0 2 2 2 0 HxlR-like helix-turn-helix SOUL PF04832.12 KFR08968.1 - 4.5e-38 131.0 0.0 5.1e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein 7tm_3 PF00003.22 KFR08969.1 - 1.1e-25 90.7 33.4 1.4e-25 90.4 33.4 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF4131 PF13567.6 KFR08969.1 - 0.013 15.2 5.2 0.013 15.2 5.2 3.6 1 1 3 4 4 4 0 Domain of unknown function (DUF4131) DUF1772 PF08592.11 KFR08969.1 - 0.61 10.4 14.8 0.48 10.7 0.2 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF1772) 7TMR-DISM_7TM PF07695.11 KFR08969.1 - 0.84 9.5 35.9 2.6 7.9 35.4 1.9 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF1345 PF07077.11 KFR08969.1 - 1 9.1 13.6 2.5 7.8 1.8 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1345) Glucos_trans_II PF14264.6 KFR08969.1 - 2.5 7.4 29.1 0.37 10.1 6.9 2.6 1 1 1 2 2 2 0 Glucosyl transferase GtrII DEAD PF00270.29 KFR08970.1 - 9.6e-48 162.3 0.2 1.5e-47 161.6 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFR08970.1 - 4.2e-32 110.8 0.6 2.7e-31 108.2 0.0 2.6 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFR08970.1 - 4.9e-06 26.7 0.0 9.7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KFR08970.1 - 0.0086 15.8 0.0 0.043 13.5 0.0 2.0 2 1 0 2 2 2 1 SWI2/SNF2 ATPase ApoL PF05461.11 KFR08971.1 - 4.2e-14 52.6 1.9 4.2e-14 52.6 1.9 1.6 2 0 0 2 2 2 1 Apolipoprotein L SseC PF04888.12 KFR08971.1 - 0.0049 16.5 2.7 1.5 8.3 0.0 2.1 1 1 1 2 2 2 2 Secretion system effector C (SseC) like family Prefoldin PF02996.17 KFR08971.1 - 0.099 12.6 1.5 8.5 6.3 0.0 2.7 3 0 0 3 3 3 0 Prefoldin subunit CENP-K PF11802.8 KFR08971.1 - 0.1 12.1 0.1 0.34 10.5 0.1 1.7 2 0 0 2 2 2 0 Centromere-associated protein K StbA PF06406.11 KFR08971.1 - 0.18 11.0 0.1 0.25 10.6 0.1 1.3 1 1 0 1 1 1 0 StbA protein Takusan PF04822.13 KFR08971.1 - 0.61 10.0 2.8 0.45 10.4 0.3 2.0 3 0 0 3 3 3 0 Takusan Linker_histone PF00538.19 KFR08972.1 - 9.9e-11 41.9 0.8 9.9e-11 41.9 0.8 2.1 2 1 0 2 2 2 1 linker histone H1 and H5 family Histone_H2A_C PF16211.5 KFR08973.1 - 3.1e-20 71.6 1.1 6.7e-20 70.5 1.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFR08973.1 - 9.1e-14 51.9 0.0 1.2e-13 51.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFR08973.1 - 0.016 15.5 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribosomal_L27A PF00828.19 KFR08973.1 - 0.076 13.7 0.1 0.094 13.4 0.1 1.2 1 0 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Frtz PF11768.8 KFR08981.1 - 0.11 10.8 0.0 0.25 9.6 0.0 1.5 1 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz cwf18 PF08315.12 KFR08982.1 - 7.8e-15 55.7 8.6 8.4e-15 55.6 8.6 1.0 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor 7tm_2 PF00002.24 KFR08986.1 - 2.2e-92 308.8 13.4 2.7e-92 308.5 13.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFR08986.1 - 2.1e-19 69.6 2.9 3.9e-19 68.7 2.9 1.5 1 0 0 1 1 1 1 Hormone receptor domain EF-hand_6 PF13405.6 KFR08989.1 - 1.2e-09 37.3 0.1 0.0086 15.9 0.0 4.3 5 1 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 KFR08989.1 - 1.4e-07 30.5 0.7 0.015 14.8 0.0 4.8 6 1 0 6 6 6 2 EF hand EF-hand_7 PF13499.6 KFR08989.1 - 0.00018 21.9 0.1 0.0039 17.6 0.0 2.7 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KFR08989.1 - 0.006 16.4 3.4 1.6 8.6 0.1 3.0 2 1 1 3 3 3 2 EF-hand domain pair DUF2267 PF10025.9 KFR08989.1 - 0.018 15.3 0.2 0.17 12.2 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) DED PF01335.21 KFR08989.1 - 0.14 12.5 0.1 1 9.7 0.0 2.3 3 0 0 3 3 3 0 Death effector domain UPF0154 PF03672.13 KFR08989.1 - 0.14 12.2 0.0 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) TMIE PF16038.5 KFR08990.1 - 6.3e-33 112.5 0.5 7.2e-33 112.3 0.5 1.0 1 0 0 1 1 1 1 TMIE protein Shisa PF13908.6 KFR08990.1 - 0.03 14.5 0.1 0.031 14.5 0.1 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DAG1 PF05454.11 KFR08990.1 - 0.054 12.9 0.1 0.056 12.8 0.1 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) EphA2_TM PF14575.6 KFR08990.1 - 0.056 14.3 0.1 0.085 13.7 0.1 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 KFR08990.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator LST1 PF05083.13 KFR08990.1 - 0.14 12.5 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 LST-1 protein MORN PF02493.20 KFR08991.1 - 8.1e-22 75.8 34.5 9.5e-07 28.4 2.4 8.9 8 1 0 8 8 8 7 MORN repeat VPS9 PF02204.18 KFR08991.1 - 1.7e-18 66.8 0.0 3.9e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Cupin_8 PF13621.6 KFR08992.1 - 5.5e-21 75.4 3.6 8.1e-21 74.9 3.6 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KFR08992.1 - 3.2e-20 72.7 0.4 1e-19 71.1 0.4 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 KFR08992.1 - 0.062 12.8 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Cupin superfamily protein GRAM PF02893.20 KFR08993.1 - 0.00027 20.8 0.2 0.00081 19.2 0.1 1.8 2 0 0 2 2 2 1 GRAM domain DUF5089 PF17002.5 KFR08993.1 - 0.0033 17.3 8.7 0.56 10.0 6.8 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF5089) wnt PF00110.19 KFR08997.1 - 5.7e-125 417.0 18.8 6.3e-125 416.8 18.8 1.0 1 0 0 1 1 1 1 wnt family Guanylate_kin PF00625.21 KFR08999.1 - 4.3e-69 231.8 0.0 5e-69 231.6 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 KFR08999.1 - 4.1e-07 30.5 0.4 1.5e-06 28.7 0.4 1.8 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 KFR08999.1 - 2.2e-05 24.5 0.1 6.2e-05 23.0 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KFR08999.1 - 2.4e-05 24.9 0.1 5.3e-05 23.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KFR08999.1 - 4.7e-05 23.9 0.0 6.5e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_33 PF13671.6 KFR08999.1 - 0.00031 20.9 0.2 0.0018 18.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KFR08999.1 - 0.00034 20.5 0.0 0.00079 19.4 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 KFR08999.1 - 0.0007 19.9 0.1 0.0022 18.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KFR08999.1 - 0.0016 18.3 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 NTPase AAA_14 PF13173.6 KFR08999.1 - 0.0022 18.0 0.1 0.0058 16.7 0.0 1.9 1 1 0 2 2 2 1 AAA domain NACHT PF05729.12 KFR08999.1 - 0.0053 16.7 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain cobW PF02492.19 KFR08999.1 - 0.0055 16.3 0.1 0.015 14.8 0.0 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 KFR08999.1 - 0.0063 16.9 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_29 PF13555.6 KFR08999.1 - 0.0082 15.9 0.1 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.6 KFR08999.1 - 0.0092 16.4 2.3 0.04 14.3 0.8 2.6 1 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFR08999.1 - 0.012 15.4 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFR08999.1 - 0.016 15.5 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KFR08999.1 - 0.016 15.6 0.3 0.04 14.3 0.0 1.8 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KFR08999.1 - 0.016 15.7 1.0 0.44 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFR08999.1 - 0.017 14.6 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 KFR08999.1 - 0.023 14.6 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain dNK PF01712.19 KFR08999.1 - 0.029 14.2 0.4 0.59 10.0 0.0 2.3 2 1 0 2 2 2 0 Deoxynucleoside kinase ATPase_2 PF01637.18 KFR08999.1 - 0.038 13.9 1.0 0.16 11.8 1.0 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 KFR08999.1 - 0.04 13.2 0.0 0.09 12.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 KFR08999.1 - 0.042 13.0 0.0 0.065 12.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.14 KFR08999.1 - 0.044 13.0 0.0 0.077 12.2 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain AAA_24 PF13479.6 KFR08999.1 - 0.054 13.2 0.2 0.22 11.3 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KFR08999.1 - 0.058 13.4 0.4 0.33 10.9 0.0 2.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 KFR08999.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF3734 PF12536.8 KFR08999.1 - 0.093 13.1 0.2 0.33 11.3 0.0 1.9 2 0 0 2 2 2 0 Patatin phospholipase TsaE PF02367.17 KFR08999.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Connexin PF00029.19 KFR09000.1 - 6.9e-109 363.1 3.8 6.9e-109 363.1 3.8 1.4 2 0 0 2 2 2 1 Connexin Apc13p PF05839.11 KFR09000.1 - 0.032 14.4 1.4 0.083 13.1 1.4 1.6 1 0 0 1 1 1 0 Apc13p protein Connexin40_C PF16791.5 KFR09000.1 - 0.29 12.4 5.1 1.7 10.0 5.1 2.3 1 1 0 1 1 1 0 Connexin 40 C-terminal domain MEIOC PF15189.6 KFR09003.1 - 2.7e-87 290.6 1.7 3.3e-87 290.3 1.7 1.1 1 0 0 1 1 1 1 Meiosis-specific coiled-coil domain-containing protein MEIOC CAMSAP_CC1 PF17095.5 KFR09003.1 - 0.032 14.1 0.4 0.078 12.8 0.4 1.6 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin I-set PF07679.16 KFR09005.1 - 3.6e-37 126.3 0.0 2.3e-17 62.8 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFR09005.1 - 5.3e-29 100.7 0.1 5.1e-13 49.4 0.0 3.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFR09005.1 - 2.1e-19 69.6 0.3 1.3e-08 35.0 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFR09005.1 - 6e-18 64.8 0.0 1.7e-07 31.3 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain PH PF00169.29 KFR09005.1 - 5.3e-09 36.5 0.2 1.7e-08 34.9 0.2 1.9 1 0 0 1 1 1 1 PH domain C2-set_2 PF08205.12 KFR09005.1 - 2.3e-08 34.0 0.3 0.00064 19.7 0.0 3.2 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFR09005.1 - 2.8e-08 33.9 0.7 0.023 14.9 0.3 4.7 2 2 0 2 2 2 2 Immunoglobulin V-set domain RhoGEF PF00621.20 KFR09005.1 - 0.00021 21.6 0.4 0.00046 20.5 0.4 1.6 1 0 0 1 1 1 1 RhoGEF domain BiPBP_C PF06832.12 KFR09005.1 - 0.00092 19.2 0.0 0.85 9.7 0.0 2.6 2 0 0 2 2 2 2 Penicillin-Binding Protein C-terminus Family IQ_SEC7_PH PF16453.5 KFR09005.1 - 0.017 15.1 0.1 0.033 14.2 0.1 1.4 1 0 0 1 1 1 0 PH domain DUF1722 PF08349.11 KFR09005.1 - 0.14 12.4 0.1 0.32 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Pkinase PF00069.25 KFR09006.1 - 3.1e-48 164.5 0.0 3.7e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR09006.1 - 4.5e-29 101.5 0.0 5.7e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR09006.1 - 0.00054 19.4 0.1 0.0012 18.2 0.0 1.6 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KFR09006.1 - 0.0042 17.0 0.0 0.0055 16.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family HIG_1_N PF04588.13 KFR09007.1 - 2.3e-18 66.1 0.7 3.8e-18 65.5 0.7 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF998 PF06197.13 KFR09007.1 - 0.049 13.2 0.2 0.06 12.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) DUF5353 PF17304.2 KFR09007.1 - 0.13 12.0 1.1 0.25 11.1 1.1 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5353) Pox_A_type_inc PF04508.12 KFR09008.1 - 0.011 15.5 5.5 1.1 9.2 0.0 4.4 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF3848 PF12959.7 KFR09008.1 - 0.028 14.5 1.1 0.028 14.5 1.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3848) BRI3BP PF14965.6 KFR09008.1 - 3.5 7.1 7.3 7.7 6.0 0.4 3.4 3 0 0 3 3 3 0 Negative regulator of p53/TP53 MBOAT PF03062.19 KFR09009.1 - 2.1e-13 50.4 16.4 3.4e-13 49.7 16.4 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family BTB PF00651.31 KFR09010.1 - 1e-34 119.1 1.8 1.9e-34 118.2 0.7 2.0 2 0 0 2 2 2 1 BTB/POZ domain Kelch_1 PF01344.25 KFR09010.1 - 1.6e-34 117.2 0.1 4.9e-10 38.8 0.0 5.7 6 0 0 6 6 6 4 Kelch motif BACK PF07707.15 KFR09010.1 - 6.1e-29 100.2 0.2 2.7e-28 98.1 0.1 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFR09010.1 - 2.2e-26 91.2 0.0 4.3e-06 26.8 0.0 5.4 3 1 2 5 5 5 5 Kelch motif Kelch_4 PF13418.6 KFR09010.1 - 7.7e-22 77.0 0.0 3.3e-06 27.0 0.0 5.6 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KFR09010.1 - 7.6e-15 54.8 0.3 0.0018 18.5 0.0 5.7 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KFR09010.1 - 1.6e-14 53.5 0.8 0.0017 18.3 0.1 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 KFR09010.1 - 4.1e-14 51.9 0.5 0.009 16.0 0.0 5.5 5 0 0 5 5 5 3 Kelch motif DUF3342 PF11822.8 KFR09010.1 - 0.00046 20.3 0.9 0.55 10.5 0.2 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF3342) RNase_H2-Ydr279 PF09468.10 KFR09010.1 - 0.42 10.8 4.2 18 5.5 4.2 2.3 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain Pro_isomerase PF00160.21 KFR09011.1 - 6.1e-46 156.6 0.1 1.7e-45 155.2 0.1 1.8 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SR-25 PF10500.9 KFR09011.1 - 0.00019 21.1 24.5 0.00019 21.1 24.5 9.7 4 3 6 10 10 10 1 Nuclear RNA-splicing-associated protein Longin PF13774.6 KFR09012.1 - 6.8e-16 58.1 0.1 1.4e-15 57.1 0.1 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain 7tm_2 PF00002.24 KFR09013.1 - 3e-84 282.2 21.2 3.9e-84 281.8 21.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFR09013.1 - 7.3e-22 77.4 3.7 1.7e-21 76.3 3.7 1.7 1 0 0 1 1 1 1 Hormone receptor domain 7tm_2 PF00002.24 KFR09014.1 - 3.7e-84 281.9 16.5 4.6e-84 281.6 16.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFR09014.1 - 8.9e-19 67.5 2.9 8.9e-19 67.5 2.9 1.8 2 0 0 2 2 2 1 Hormone receptor domain 7tm_2 PF00002.24 KFR09015.1 - 1.2e-86 290.0 12.0 1.2e-86 290.0 12.0 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFR09015.1 - 1.1e-28 99.2 1.7 1.1e-28 99.2 1.7 2.2 2 0 0 2 2 2 1 Hormone receptor domain Na_Ca_ex PF01699.24 KFR09015.1 - 0.0061 16.5 2.2 0.0061 16.5 2.2 2.3 2 0 0 2 2 2 1 Sodium/calcium exchanger protein Insulin_TMD PF17870.1 KFR09015.1 - 0.047 13.8 0.6 0.17 12.0 0.6 2.0 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment 7tm_2 PF00002.24 KFR09016.1 - 7.6e-85 284.1 18.9 9.7e-85 283.8 18.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFR09016.1 - 8.9e-21 74.0 1.3 2.1e-20 72.8 1.3 1.7 1 0 0 1 1 1 1 Hormone receptor domain Dicty_CAR PF05462.11 KFR09016.1 - 0.00023 20.4 15.9 0.00035 19.8 15.9 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor MIP PF00230.20 KFR09018.1 - 2.8e-80 269.3 10.0 3.3e-80 269.0 10.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF4205 PF13898.6 KFR09019.1 - 3.2e-143 476.8 0.0 3.7e-143 476.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) FAS_meander PF17951.1 KFR09020.1 - 0.11 12.4 0.0 3.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Fatty acid synthase meander beta sheet domain 7tm_2 PF00002.24 KFR09021.1 - 1.8e-76 256.7 23.5 2.2e-76 256.4 23.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFR09021.1 - 5.2e-19 68.3 2.4 1.2e-18 67.2 2.4 1.6 1 0 0 1 1 1 1 Hormone receptor domain zf-C2H2 PF00096.26 KFR09022.1 - 2.6e-66 216.5 104.4 5.5e-08 32.9 1.5 12.1 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFR09022.1 - 4.9e-52 172.1 96.7 1.3e-09 38.1 0.7 13.1 13 0 0 13 13 13 11 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR09022.1 - 2.4e-41 136.8 97.2 0.00017 22.2 0.7 12.1 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFR09022.1 - 1.7e-13 50.0 73.4 0.00087 19.0 0.7 11.9 12 0 0 12 12 12 7 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFR09022.1 - 1.9e-11 43.6 92.6 0.0034 17.4 0.5 13.2 12 3 0 12 12 11 7 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFR09022.1 - 5.7e-11 42.6 46.2 9.8e-05 22.6 4.8 6.1 1 1 5 6 6 6 5 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KFR09022.1 - 1.5e-10 41.1 33.3 0.26 11.6 0.2 10.0 10 0 0 10 10 10 4 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFR09022.1 - 2.5e-07 30.1 61.3 0.62 9.7 0.5 11.8 11 1 1 12 12 12 7 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFR09022.1 - 3.5e-05 23.8 69.1 0.00052 20.1 3.5 8.5 5 4 3 9 9 9 3 Zinc ribbon domain C1_4 PF07975.12 KFR09022.1 - 6e-05 23.2 50.3 0.0028 17.8 3.6 6.9 2 2 4 7 7 7 4 TFIIH C1-like domain ADK_lid PF05191.14 KFR09022.1 - 0.0091 16.0 46.7 0.027 14.5 3.0 8.2 5 4 1 6 6 6 1 Adenylate kinase, active site lid zinc_ribbon_15 PF17032.5 KFR09022.1 - 0.021 15.6 50.4 0.3 11.9 3.1 6.2 3 2 3 6 6 6 0 zinc-ribbon family zf-H2C2_5 PF13909.6 KFR09022.1 - 0.021 14.6 1.3 0.021 14.6 1.3 11.7 11 2 0 11 11 11 0 C2H2-type zinc-finger domain Elf1 PF05129.13 KFR09022.1 - 0.034 14.2 0.6 0.034 14.2 0.6 7.9 2 2 7 9 9 9 0 Transcription elongation factor Elf1 like BolA PF01722.18 KFR09022.1 - 0.18 12.1 13.3 5 7.5 0.3 5.7 4 2 1 5 5 5 0 BolA-like protein GAGA PF09237.11 KFR09022.1 - 0.18 11.6 28.0 0.56 10.0 0.1 6.7 4 1 4 8 8 8 0 GAGA factor Zn_ribbon_recom PF13408.6 KFR09022.1 - 0.96 10.0 0.1 0.96 10.0 0.1 8.9 6 3 1 7 7 5 0 Recombinase zinc beta ribbon domain zf-met PF12874.7 KFR09022.1 - 2.9 8.4 63.3 1.8 9.0 0.7 10.1 10 1 0 10 10 9 0 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 KFR09022.1 - 8.2 6.4 10.3 16 5.4 0.0 4.6 5 1 1 6 6 6 0 C2H2 type zinc-finger (1 copy) LIM PF00412.22 KFR09022.1 - 9.7 6.5 62.2 0.32 11.3 1.6 9.3 2 2 5 9 9 7 0 LIM domain zf-H2C2_2 PF13465.6 KFR09024.1 - 1.7e-68 224.2 69.1 9.3e-08 32.2 0.1 12.7 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFR09024.1 - 1.6e-62 204.6 83.3 4.5e-06 26.8 1.0 12.1 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR09024.1 - 1.9e-37 124.7 80.3 0.0026 18.4 0.7 12.1 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFR09024.1 - 1.1e-12 47.9 44.5 0.017 15.4 0.1 12.0 12 0 0 12 12 12 4 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFR09024.1 - 2.1e-06 27.2 43.9 0.43 10.2 0.1 11.1 11 0 0 11 11 11 3 Ubiquitin-Binding Zinc Finger zf-C2H2_8 PF15909.5 KFR09024.1 - 3.2e-06 27.3 33.7 0.078 13.3 1.4 6.1 1 1 4 6 6 6 3 C2H2-type zinc ribbon zf-LYAR PF08790.11 KFR09024.1 - 3.3e-05 23.7 57.0 0.15 12.0 0.2 11.5 12 0 0 12 12 12 5 LYAR-type C2HC zinc finger zf-C2H2_11 PF16622.5 KFR09024.1 - 9.2e-05 22.1 56.4 0.14 11.9 0.1 11.1 11 0 0 11 11 11 4 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFR09024.1 - 0.0065 16.5 1.0 0.0065 16.5 1.0 11.8 13 0 0 13 13 13 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFR09024.1 - 0.014 15.5 53.7 0.13 12.4 2.3 9.0 4 4 5 9 9 9 0 Zinc ribbon domain zf-C2H2_3rep PF18868.1 KFR09024.1 - 0.031 15.0 39.1 0.38 11.4 1.9 8.7 2 1 3 6 6 6 0 Zinc finger C2H2-type, 3 repeats Adhesin_P1 PF03257.13 KFR09024.1 - 0.056 14.0 0.0 9.5 6.8 0.0 3.4 3 1 1 4 4 4 0 Mycoplasma adhesin P1 zinc_ribbon_15 PF17032.5 KFR09024.1 - 0.061 14.1 36.8 2.5 8.9 0.5 5.9 1 1 5 7 7 7 0 zinc-ribbon family LIM PF00412.22 KFR09024.1 - 0.22 11.8 56.0 0.44 10.8 2.5 9.4 3 3 5 9 9 9 0 LIM domain BolA PF01722.18 KFR09024.1 - 0.27 11.5 13.7 11 6.3 0.4 6.3 2 2 4 6 6 6 0 BolA-like protein zf-C2HE PF16278.5 KFR09024.1 - 1 9.9 65.0 1 9.9 0.8 10.9 4 4 5 10 10 9 0 C2HE / C2H2 / C2HC zinc-binding finger zf-AN1 PF01428.16 KFR09024.1 - 2.7 8.2 68.5 1.9 8.8 4.5 11.7 9 3 2 12 12 12 0 AN1-like Zinc finger HGTP_anticodon PF03129.20 KFR09026.1 - 9.9e-24 83.3 0.1 4.6e-23 81.2 0.0 2.2 2 1 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KFR09026.1 - 2.8e-10 40.4 0.1 1.1e-09 38.5 0.0 2.2 3 1 0 3 3 3 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 KFR09026.1 - 1.5e-08 34.6 6.1 5.8e-08 32.8 6.1 2.1 1 0 0 1 1 1 1 WHEP-TRS domain EcoRII-C PF09019.11 KFR09026.1 - 0.051 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 EcoRII C terminal OS-D PF03392.13 KFR09026.1 - 0.053 13.6 1.1 0.091 12.9 0.1 1.9 2 0 0 2 2 2 0 Insect pheromone-binding family, A10/OS-D NIF PF03031.18 KFR09029.1 - 6.6e-53 178.7 0.0 8.6e-53 178.3 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Gelsolin PF00626.22 KFR09030.1 - 2.8e-85 280.3 0.0 1.7e-17 63.0 0.0 6.6 6 0 0 6 6 6 6 Gelsolin repeat PI-PLC-X PF00388.19 KFR09031.1 - 4.7e-68 227.3 0.1 1e-67 226.2 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFR09031.1 - 5.4e-45 152.5 0.0 1.1e-44 151.5 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 KFR09031.1 - 3.1e-35 120.5 1.5 9.1e-35 119.0 0.2 2.6 3 0 0 3 3 3 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 KFR09031.1 - 3.3e-20 72.3 0.2 7.5e-20 71.1 0.2 1.6 1 0 0 1 1 1 1 C2 domain EF-hand_10 PF14788.6 KFR09031.1 - 0.00041 20.1 0.5 0.00088 19.1 0.5 1.6 1 0 0 1 1 1 1 EF hand BDM PF10684.9 KFR09031.1 - 0.093 13.1 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Putative biofilm-dependent modulation protein Thiolase_N PF00108.23 KFR09032.1 - 2.7e-79 266.2 1.0 4.3e-79 265.6 1.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFR09032.1 - 5.5e-50 168.1 0.3 1.1e-49 167.1 0.3 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KFR09032.1 - 9.2e-05 22.2 1.5 0.023 14.5 0.1 2.8 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 KFR09032.1 - 0.00022 21.3 0.0 0.00069 19.7 0.0 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.26 KFR09032.1 - 0.01 15.5 2.6 0.027 14.0 0.6 2.3 2 1 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Pkinase PF00069.25 KFR09033.1 - 1.8e-65 221.0 0.0 2.6e-65 220.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR09033.1 - 1.2e-39 136.2 0.0 1.8e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.24 KFR09033.1 - 1e-12 47.8 0.0 3e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 PB1 domain Kinase-like PF14531.6 KFR09033.1 - 9.6e-05 21.8 0.0 0.0062 15.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.11 KFR09033.1 - 0.045 12.8 0.2 1.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Seadornavirus VP7 DUF1830 PF08865.11 KFR09034.1 - 0.018 15.0 0.1 0.019 14.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) TIR_2 PF13676.6 KFR09035.1 - 1.3e-12 48.4 0.0 1.7e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 KFR09035.1 - 9e-11 41.9 0.2 1.8e-10 40.9 0.1 1.5 1 1 1 2 2 2 1 TIR domain MFS_1 PF07690.16 KFR09037.1 - 1.5e-32 112.9 37.1 1e-28 100.3 24.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFR09037.1 - 2.1e-32 112.6 19.8 5.7e-32 111.2 19.8 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 KFR09037.1 - 3.4e-05 22.6 13.4 0.00031 19.5 3.6 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein TPR_8 PF13181.6 KFR09037.1 - 0.025 14.8 0.0 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Sugar_tr PF00083.24 KFR09038.1 - 8.9e-37 127.0 12.3 1.1e-36 126.8 12.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFR09038.1 - 4.5e-31 108.1 18.1 4.5e-31 108.1 18.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 KFR09038.1 - 4.8e-07 28.7 10.4 8.5e-05 21.3 2.1 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein TPR_8 PF13181.6 KFR09038.1 - 0.023 14.9 0.0 0.1 12.8 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat LIM PF00412.22 KFR09039.1 - 2.7e-08 33.9 11.1 3e-08 33.7 11.1 1.0 1 0 0 1 1 1 1 LIM domain CSRNP_N PF16019.5 KFR09041.1 - 2.3e-104 348.1 9.5 3.7e-104 347.4 9.5 1.3 1 0 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus CxC2 PF18803.1 KFR09133.1 - 4.9e-05 23.4 0.0 0.00014 22.0 0.0 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases LRR_6 PF13516.6 KFR09133.1 - 0.013 15.5 4.6 2.1 8.6 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 KFR09133.1 - 0.097 13.3 8.2 23 6.0 0.1 5.3 5 1 0 5 5 5 0 Leucine Rich Repeat Peptidase_M26_N PF05342.14 KFR09133.1 - 0.14 11.6 0.2 0.28 10.6 0.0 1.5 2 0 0 2 2 2 0 M26 IgA1-specific Metallo-endopeptidase N-terminal region p25-alpha PF05517.12 KFR09135.1 - 1.2e-67 227.0 4.9 1.3e-67 226.8 4.9 1.0 1 0 0 1 1 1 1 p25-alpha Rep_3 PF01051.21 KFR09135.1 - 0.024 14.4 0.3 0.031 14.1 0.3 1.1 1 0 0 1 1 1 0 Initiator Replication protein HGD-D PF06050.13 KFR09135.1 - 0.065 13.0 0.0 0.067 12.9 0.0 1.0 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component DUF3512 PF12024.8 KFR09137.1 - 1.6e-83 279.8 0.5 1.6e-83 279.8 0.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3512) Bromodomain PF00439.25 KFR09137.1 - 6.8e-25 86.9 0.1 1.3e-23 82.9 0.1 2.4 2 0 0 2 2 2 1 Bromodomain Zip PF02535.22 KFR09137.1 - 0.14 11.3 1.7 0.23 10.7 1.7 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter CPSF100_C PF13299.6 KFR09137.1 - 0.59 10.3 7.9 0.55 10.4 4.5 2.5 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal NPR3 PF03666.13 KFR09137.1 - 0.6 8.8 8.8 0.086 11.6 4.2 1.8 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 PPL5 PF18168.1 KFR09137.1 - 2.1 7.5 7.3 4.1 6.6 7.3 1.4 1 0 0 1 1 1 0 Prim-pol family 5 NARP1 PF12569.8 KFR09137.1 - 2.2 7.1 16.2 4.2 6.2 16.2 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SR-25 PF10500.9 KFR09137.1 - 4.3 6.9 23.8 0.044 13.4 14.7 2.3 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 KFR09137.1 - 4.6 5.4 14.8 7.8 4.7 14.8 1.3 1 0 0 1 1 1 0 CDC45-like protein AAA PF00004.29 KFR09138.1 - 6e-31 107.6 0.0 9.5e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFR09138.1 - 4.2e-07 30.3 0.2 2.4e-06 27.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFR09138.1 - 4.4e-06 27.3 0.1 3.7e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFR09138.1 - 1.4e-05 25.5 0.0 3e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KFR09138.1 - 4.1e-05 23.6 0.0 9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFR09138.1 - 0.0002 21.5 0.1 0.00035 20.7 0.1 1.5 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KFR09138.1 - 0.00026 20.8 0.6 0.0026 17.5 0.0 2.5 2 1 0 2 2 2 1 Cytidylate kinase RuvB_N PF05496.12 KFR09138.1 - 0.0007 19.4 0.0 0.0045 16.7 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 KFR09138.1 - 0.00078 19.1 0.1 0.1 12.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFR09138.1 - 0.0008 19.4 0.1 0.002 18.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 KFR09138.1 - 0.0013 18.7 0.8 1.1 9.1 0.0 2.4 1 1 1 2 2 2 2 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KFR09138.1 - 0.0014 18.4 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 KFR09138.1 - 0.0019 17.9 0.0 0.0047 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 KFR09138.1 - 0.0024 17.9 0.0 0.0049 16.9 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KFR09138.1 - 0.0025 17.8 0.2 0.01 15.8 0.2 2.1 1 1 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 KFR09138.1 - 0.0025 18.2 0.0 0.0062 16.9 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 KFR09138.1 - 0.0025 17.5 0.1 0.0064 16.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KFR09138.1 - 0.0026 18.0 0.0 0.0067 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFR09138.1 - 0.0029 17.4 0.0 0.006 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 KFR09138.1 - 0.003 16.8 0.4 0.82 8.8 0.1 2.3 1 1 1 2 2 2 1 KAP family P-loop domain AAA_7 PF12775.7 KFR09138.1 - 0.0037 16.8 0.0 0.014 15.0 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region Viral_helicase1 PF01443.18 KFR09138.1 - 0.0042 16.9 0.0 0.0086 15.8 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 KFR09138.1 - 0.0047 16.1 0.1 0.017 14.3 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF815) PduV-EutP PF10662.9 KFR09138.1 - 0.005 16.6 0.0 0.013 15.3 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 KFR09138.1 - 0.0052 17.3 0.1 0.013 16.0 0.0 1.7 2 0 0 2 2 1 1 ABC transporter TIP49 PF06068.13 KFR09138.1 - 0.0094 15.2 0.1 0.017 14.3 0.0 1.5 2 0 0 2 2 2 1 TIP49 P-loop domain ATPase PF06745.13 KFR09138.1 - 0.012 15.0 0.1 0.66 9.3 0.0 2.4 2 0 0 2 2 2 0 KaiC FtsK_SpoIIIE PF01580.18 KFR09138.1 - 0.012 15.0 0.1 2 7.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.6 KFR09138.1 - 0.022 15.2 0.0 0.054 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KFR09138.1 - 0.028 13.8 0.0 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 KFR09138.1 - 0.037 13.9 1.6 0.08 12.8 0.5 2.2 2 1 0 2 2 1 0 Rad17 P-loop domain AAA_19 PF13245.6 KFR09138.1 - 0.039 14.3 0.0 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KFR09138.1 - 0.042 13.3 0.0 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_2 PF07724.14 KFR09138.1 - 0.046 13.8 0.0 0.098 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF2075 PF09848.9 KFR09138.1 - 0.078 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zot PF05707.12 KFR09138.1 - 0.1 12.2 0.3 2.1 8.0 0.3 2.3 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_3 PF07726.11 KFR09138.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Endostatin PF06482.11 KFR09140.1 - 5e-90 302.2 0.1 5.6e-90 302.0 0.1 1.0 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin DUF1554 PF07588.11 KFR09140.1 - 0.031 14.1 0.6 1 9.1 0.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1554) Pkinase PF00069.25 KFR09141.1 - 4e-35 121.5 0.0 6.2e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR09141.1 - 3.8e-32 111.6 0.0 5.1e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.12 KFR09141.1 - 2.5e-17 62.0 0.4 4.9e-17 61.1 0.4 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.23 KFR09141.1 - 8.9e-09 36.3 8.0 8.9e-09 36.3 8.0 1.7 2 0 0 2 2 2 1 Activin types I and II receptor domain Pkinase_fungal PF17667.1 KFR09141.1 - 2.3e-05 23.3 0.5 0.00022 20.2 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFR09141.1 - 0.01 15.7 0.0 0.021 14.7 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFR09141.1 - 0.033 13.1 0.0 0.17 10.8 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain FTA2 PF13095.6 KFR09141.1 - 0.097 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kazal_2 PF07648.15 KFR09142.1 - 1.6e-11 44.1 39.0 2.5e-05 24.3 0.6 5.6 5 0 0 5 5 5 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFR09142.1 - 2.1e-11 43.6 21.2 0.0013 18.7 1.9 5.1 2 1 1 3 3 3 3 Kazal-type serine protease inhibitor domain Ldl_recept_a PF00057.18 KFR09142.1 - 0.0051 17.0 3.0 0.0051 17.0 3.0 7.1 6 0 0 6 6 6 1 Low-density lipoprotein receptor domain class A VWC PF00093.18 KFR09142.1 - 0.015 15.6 5.3 0.015 15.6 5.3 9.7 7 3 4 11 11 11 0 von Willebrand factor type C domain DNA_pol_E_B PF04042.16 KFR09142.1 - 0.018 14.4 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B zf-C2H2_3rep PF18868.1 KFR09143.1 - 0.00062 20.5 2.0 0.00062 20.5 2.0 4.4 3 1 2 5 5 5 1 Zinc finger C2H2-type, 3 repeats Homeodomain PF00046.29 KFR09143.1 - 0.0036 17.1 0.1 0.01 15.7 0.1 1.7 1 0 0 1 1 1 1 Homeodomain Zn-C2H2_12 PF18112.1 KFR09143.1 - 0.02 15.3 0.4 0.02 15.3 0.4 2.8 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain DUF2719 PF10891.8 KFR09143.1 - 0.085 12.8 4.8 0.74 9.7 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2719) zf-C2H2_4 PF13894.6 KFR09143.1 - 0.17 12.8 67.5 0.095 13.6 0.7 9.8 10 0 0 10 10 10 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KFR09143.1 - 0.27 10.9 26.6 0.17 11.6 1.1 5.3 5 0 0 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain PRP21_like_P PF12230.8 KFR09143.1 - 0.34 10.8 3.1 1.1 9.1 0.1 2.8 3 0 0 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein GAGA PF09237.11 KFR09143.1 - 6.1 6.7 6.0 21 5.0 0.1 3.5 4 0 0 4 4 4 0 GAGA factor RBFA PF02033.18 KFR09144.1 - 1.4e-12 47.9 0.3 4.9e-12 46.2 0.0 2.0 2 0 0 2 2 2 1 Ribosome-binding factor A HTH_OrfB_IS605 PF12323.8 KFR09144.1 - 0.18 11.3 0.7 4.7 6.8 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Colicin_immun PF09204.10 KFR09144.1 - 1.9 9.1 6.5 6.1 7.4 0.0 3.0 3 0 0 3 3 3 0 Bacterial self-protective colicin-like immunity 2-Hacid_dh_C PF02826.19 KFR09145.1 - 2.5e-58 196.4 0.0 4.3e-58 195.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFR09145.1 - 3.4e-18 65.6 0.0 3.8e-18 65.5 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFR09145.1 - 3.5e-09 37.0 0.1 5.7e-09 36.3 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 KFR09145.1 - 0.00036 19.9 0.0 0.00062 19.1 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 KFR09145.1 - 0.016 16.0 0.0 0.026 15.4 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold AdoHcyase_NAD PF00670.21 KFR09145.1 - 0.019 15.0 0.0 3.6 7.7 0.0 2.2 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.17 KFR09145.1 - 0.044 14.4 0.0 0.087 13.4 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 KFR09145.1 - 0.05 13.2 0.1 0.071 12.7 0.1 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 KFR09146.1 - 2.1e-59 199.9 0.1 2.8e-59 199.4 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFR09146.1 - 4.9e-20 71.6 0.1 5.5e-20 71.4 0.1 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFR09146.1 - 1.8e-10 41.2 0.3 4e-10 40.1 0.2 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 KFR09146.1 - 9.7e-05 21.8 0.0 0.00015 21.1 0.0 1.4 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 KFR09146.1 - 0.00043 21.1 0.0 0.00087 20.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 KFR09146.1 - 0.0012 19.4 0.0 0.0028 18.2 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_N PF05222.15 KFR09146.1 - 0.0049 17.2 0.0 0.0093 16.3 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain IlvN PF07991.12 KFR09146.1 - 0.011 15.4 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 KFR09146.1 - 0.035 14.2 0.1 0.081 13.0 0.1 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KFR09146.1 - 0.041 14.2 2.1 0.37 11.1 0.0 2.8 3 0 0 3 3 3 0 TrkA-N domain AdoHcyase_NAD PF00670.21 KFR09146.1 - 0.051 13.6 0.0 12 5.9 0.0 2.3 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DIM1 PF02966.16 KFR09147.1 - 3.3e-70 234.0 0.2 3.7e-70 233.9 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KFR09147.1 - 3.1e-06 27.1 0.0 3.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KFR09147.1 - 0.016 15.5 0.3 0.025 14.9 0.3 1.4 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_7 PF13899.6 KFR09147.1 - 0.064 13.4 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like PQ-loop PF04193.14 KFR09148.1 - 5.3e-32 109.4 8.5 2.2e-19 69.0 0.1 3.6 3 1 1 4 4 4 2 PQ loop repeat ER_lumen_recept PF00810.18 KFR09148.1 - 1.1e-06 29.5 2.9 0.0078 17.0 0.8 2.5 2 1 0 2 2 2 2 ER lumen protein retaining receptor MtN3_slv PF03083.16 KFR09148.1 - 0.016 15.2 8.5 0.054 13.5 2.3 2.8 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Ion_trans PF00520.31 KFR09149.1 - 3.3e-38 131.3 3.5 4.6e-38 130.8 3.5 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFR09149.1 - 4.4e-28 97.5 0.0 9.4e-28 96.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFR09149.1 - 1.8e-14 53.5 4.5 5.5e-14 51.9 2.3 2.5 2 0 0 2 2 2 1 Ion channel RHD_DNA_bind PF00554.22 KFR09151.1 - 9.4e-26 90.8 0.1 3.4e-25 88.9 0.1 2.0 1 1 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.5 KFR09151.1 - 2.9e-24 85.1 0.1 4.9e-24 84.3 0.1 1.4 1 0 0 1 1 1 1 Rel homology dimerisation domain TIG PF01833.24 KFR09151.1 - 1.7e-06 28.0 0.0 6.2e-06 26.2 0.0 2.1 1 0 0 1 1 1 1 IPT/TIG domain PhoLip_ATPase_C PF16212.5 KFR09152.1 - 1.5e-52 178.9 19.9 1.5e-52 178.9 19.9 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFR09152.1 - 5.2e-20 70.9 1.2 1.5e-19 69.4 1.2 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFR09152.1 - 1.2e-14 55.1 0.1 1.2e-11 45.4 0.1 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFR09152.1 - 1.3e-13 50.8 0.0 3.7e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 KFR09152.1 - 1.1e-07 31.8 0.0 7.8e-07 29.1 0.0 2.4 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFR09152.1 - 0.00063 19.6 0.0 0.0018 18.1 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4174 PF13778.6 KFR09152.1 - 0.1 13.1 0.1 0.3 11.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) zf-C2H2 PF00096.26 KFR09153.1 - 3.3e-31 106.0 73.7 5.9e-05 23.3 0.2 10.0 10 0 0 10 10 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR09153.1 - 1e-29 100.6 74.5 0.00072 20.2 1.1 10.5 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFR09153.1 - 3.8e-27 93.5 57.6 4.9e-07 29.9 1.1 10.8 11 0 0 11 11 11 7 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFR09153.1 - 4.8e-19 68.1 42.8 0.00096 19.4 1.0 9.9 10 0 0 10 10 10 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFR09153.1 - 2.1e-18 66.0 59.8 0.0027 18.0 0.4 9.9 10 0 0 10 10 10 8 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KFR09153.1 - 0.00037 20.9 36.4 0.00045 20.6 2.9 6.7 5 3 1 6 6 6 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 KFR09153.1 - 0.0012 18.8 66.8 0.0075 16.2 1.6 10.0 10 0 0 10 10 10 5 C2H2-type zinc finger DUF3268 PF11672.8 KFR09153.1 - 0.0046 17.3 17.9 0.4 11.0 0.2 4.3 4 0 0 4 4 4 2 zinc-finger-containing domain zf-Di19 PF05605.12 KFR09153.1 - 0.0097 16.2 36.6 0.075 13.3 2.6 5.2 4 1 1 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding NinF PF05810.12 KFR09153.1 - 0.094 12.6 0.1 0.49 10.3 0.1 2.2 1 0 0 1 1 1 0 NinF protein zf-C2H2_2 PF12756.7 KFR09153.1 - 0.21 12.0 45.1 0.55 10.6 2.2 8.8 4 4 5 9 9 9 0 C2H2 type zinc-finger (2 copies) BolA PF01722.18 KFR09153.1 - 0.35 11.2 6.5 16 5.9 0.1 4.3 4 0 0 4 4 4 0 BolA-like protein DUF2225 PF09986.9 KFR09153.1 - 0.48 10.1 0.0 0.48 10.1 0.0 2.7 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) Y_Y_Y PF07495.13 KFR09155.1 - 4.8e-17 61.7 0.0 0.0017 18.2 0.0 5.4 5 0 0 5 5 5 4 Y_Y_Y domain Big_9 PF17963.1 KFR09155.1 - 4.5e-12 46.5 18.8 0.0046 17.7 0.3 5.3 5 0 0 5 5 5 4 Bacterial Ig domain PKD PF00801.20 KFR09155.1 - 1.1e-11 44.4 7.5 0.17 11.7 0.0 5.5 5 0 0 5 5 5 4 PKD domain REJ PF02010.15 KFR09155.1 - 1.1e-10 40.9 2.5 3.6e-07 29.3 0.3 3.8 1 1 2 3 3 3 2 REJ domain DUF4625 PF15418.6 KFR09155.1 - 1.3e-07 31.9 0.2 3.3 8.0 0.0 4.5 4 0 0 4 4 4 2 Domain of unknown function (DUF4625) DUF5013 PF16405.5 KFR09155.1 - 2e-05 24.9 0.1 0.14 12.4 0.0 4.5 5 0 0 5 5 4 1 Domain of unknown function (DUF5013) Wzt_C PF14524.6 KFR09155.1 - 2.5e-05 24.4 0.1 0.62 10.1 0.0 5.0 6 0 0 6 6 6 1 Wzt C-terminal domain He_PIG PF05345.12 KFR09155.1 - 2.7e-05 24.3 5.9 5.2 7.3 0.0 4.9 5 0 0 5 5 4 1 Putative Ig domain DUF4998 PF16389.5 KFR09155.1 - 4.7e-05 23.1 1.9 2.2 7.9 0.0 4.7 5 0 0 5 5 5 2 Domain of unknown function MANEC PF07502.14 KFR09155.1 - 0.00092 19.4 4.0 0.00092 19.4 4.0 2.1 2 0 0 2 2 2 1 MANEC domain Cadherin PF00028.17 KFR09155.1 - 0.007 16.8 1.4 41 4.7 0.1 4.3 4 0 0 4 4 4 0 Cadherin domain DUF5011 PF16403.5 KFR09155.1 - 0.026 14.6 0.7 1.1e+02 3.0 0.0 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF5011) FixG_C PF11614.8 KFR09155.1 - 0.043 14.0 4.8 24 5.2 0.1 4.4 5 0 0 5 5 4 0 IG-like fold at C-terminal of FixG, putative oxidoreductase DUF4388 PF14332.6 KFR09155.1 - 0.048 13.9 0.0 0.91 9.8 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4388) DUF1180 PF06679.12 KFR09155.1 - 0.077 13.4 0.2 0.36 11.2 0.0 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF1180) Cadherin_5 PF17892.1 KFR09155.1 - 0.11 12.5 8.0 12 6.0 0.1 4.8 5 0 0 5 5 4 0 Cadherin-like domain PAN_4 PF14295.6 KFR09155.1 - 0.27 11.2 5.6 0.31 11.0 3.1 2.3 2 0 0 2 2 2 0 PAN domain Invasin_D3 PF09134.10 KFR09155.1 - 0.32 11.3 7.1 33 4.9 0.7 4.5 2 1 2 4 4 4 0 Invasin, domain 3 Big_3_5 PF16640.5 KFR09155.1 - 6.7 7.0 11.8 48 4.2 2.6 4.5 4 1 0 4 4 4 0 Bacterial Ig-like domain (group 3) Aldedh PF00171.22 KFR09156.1 - 1.1e-132 442.8 0.7 1.4e-132 442.5 0.7 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FG-GAP PF01839.23 KFR09157.1 - 6.2e-27 93.4 32.4 2.1e-09 37.3 2.0 5.5 5 1 0 5 5 5 4 FG-GAP repeat Zn_dep_PLPC PF00882.18 KFR09157.1 - 2e-23 83.3 2.1 4.3e-23 82.2 2.1 1.6 1 0 0 1 1 1 1 Zinc dependent phospholipase C VCBS PF13517.6 KFR09157.1 - 1.9e-14 54.0 10.7 3.8e-07 30.6 0.7 4.3 3 1 1 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BBS2_Mid PF14783.6 KFR09157.1 - 0.021 14.8 0.1 20 5.3 0.0 4.2 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region TcdB_toxin_midN PF12256.8 KFR09157.1 - 0.038 13.3 3.0 1.1 8.6 0.1 3.4 3 1 1 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region CcmB PF03379.13 KFR09158.1 - 0.062 12.8 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 CcmB protein Neurensin PF14927.6 KFR09159.1 - 2.8e-51 172.7 0.1 3.5e-51 172.4 0.1 1.1 1 0 0 1 1 1 1 Neurensin DUF624 PF04854.14 KFR09159.1 - 0.075 13.1 1.4 0.26 11.4 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF624 COX8 PF02285.15 KFR09159.1 - 9.5 6.2 7.3 0.39 10.6 1.0 1.8 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII Hormone_1 PF00103.20 KFR09160.1 - 8.5e-72 241.4 0.0 9.6e-72 241.2 0.0 1.0 1 0 0 1 1 1 1 Somatotropin hormone family KIAA1430 PF13879.6 KFR09160.1 - 0.047 14.4 0.1 0.39 11.5 0.0 2.1 2 0 0 2 2 2 0 KIAA1430 homologue UPF0004 PF00919.20 KFR09161.1 - 2.9e-21 75.3 0.0 5.9e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 KFR09161.1 - 6.4e-19 68.9 0.1 1.7e-18 67.6 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily TRAM PF01938.20 KFR09161.1 - 1.5e-05 24.9 0.0 3.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 TRAM domain Styelin PF17562.2 KFR09161.1 - 0.0098 16.2 0.0 0.07 13.5 0.0 2.3 2 0 0 2 2 2 1 Styelin E2F_CC-MB PF16421.5 KFR09162.1 - 7.4e-34 116.0 0.5 1.2e-33 115.3 0.5 1.3 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 KFR09162.1 - 5e-26 90.5 0.7 1.3e-25 89.2 0.2 1.9 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain MBOAT PF03062.19 KFR09163.1 - 2.5e-30 106.0 12.3 2.5e-30 106.0 12.3 2.1 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family HLH PF00010.26 KFR09164.1 - 5.2e-14 51.9 0.1 7.2e-14 51.5 0.1 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain IBR PF01485.21 KFR09166.1 - 1.4e-18 66.8 23.1 2.3e-13 50.1 7.6 4.8 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KFR09166.1 - 0.019 15.3 58.5 0.044 14.1 8.4 5.1 4 1 0 4 4 4 0 Ring finger domain DEK_C PF08766.11 KFR09167.1 - 9.4e-18 63.9 0.2 2.2e-17 62.7 0.2 1.7 1 0 0 1 1 1 1 DEK C terminal domain SAP PF02037.27 KFR09167.1 - 6e-06 25.9 1.6 1.6e-05 24.5 0.1 2.7 2 0 0 2 2 2 1 SAP domain DUF2052 PF09747.9 KFR09167.1 - 0.021 14.9 32.9 0.16 12.1 14.0 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) ORC6 PF05460.13 KFR09167.1 - 2.5 7.3 35.0 0.034 13.4 21.6 2.1 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) MDM1 PF15501.6 KFR09167.1 - 3.6 6.6 47.1 0.064 12.4 27.1 2.1 2 0 0 2 2 2 0 Nuclear protein MDM1 eIF-3c_N PF05470.12 KFR09167.1 - 8.3 4.6 27.7 0.52 8.5 3.4 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.14 KFR09167.1 - 8.5 4.5 36.7 1.8 6.7 7.9 2.2 2 0 0 2 2 2 0 CDC45-like protein Hid1 PF12722.7 KFR09167.1 - 10 4.1 26.9 0.81 7.7 12.7 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Amino_oxidase PF01593.24 KFR09168.1 - 9.5e-89 298.7 0.0 1.5e-88 298.1 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFR09168.1 - 1.3e-11 44.6 0.1 3e-11 43.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain zf-CW PF07496.15 KFR09168.1 - 7.2e-11 41.9 1.9 2.8e-10 40.1 1.9 2.1 1 0 0 1 1 1 1 CW-type Zinc Finger Thi4 PF01946.17 KFR09168.1 - 1.6e-08 34.1 0.1 8.4e-08 31.7 0.1 2.0 2 0 0 2 2 2 1 Thi4 family SWIRM PF04433.17 KFR09168.1 - 4e-08 33.5 0.1 1e-07 32.2 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain Pyr_redox_2 PF07992.14 KFR09168.1 - 2.7e-07 30.1 0.1 1.4e-05 24.5 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFR09168.1 - 5.5e-07 30.1 0.9 7.8e-05 23.2 0.3 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFR09168.1 - 2e-06 27.2 1.1 1.1e-05 24.7 1.7 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KFR09168.1 - 2.2e-06 26.6 1.7 2e-05 23.5 0.8 2.6 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 KFR09168.1 - 6.7e-06 25.6 0.3 8e-05 22.0 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KFR09168.1 - 8.6e-06 25.2 4.3 0.00038 19.8 1.7 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFR09168.1 - 4.4e-05 23.2 3.4 0.00037 20.2 3.5 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFR09168.1 - 9e-05 21.7 0.2 0.00016 20.8 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KFR09168.1 - 0.00014 21.4 0.4 0.00024 20.6 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KFR09168.1 - 0.00019 20.8 0.0 0.0007 19.0 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KFR09168.1 - 0.00087 18.5 0.7 0.0015 17.7 0.7 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KFR09168.1 - 0.0014 18.7 0.8 0.082 12.9 0.2 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KFR09168.1 - 0.01 15.2 0.2 0.018 14.3 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 KFR09168.1 - 0.013 15.1 0.3 0.024 14.2 0.3 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ThiF PF00899.21 KFR09168.1 - 0.091 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 ThiF family zf-C3HC4 PF00097.25 KFR09168.1 - 0.098 12.5 4.0 0.39 10.6 4.0 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NAD_binding_7 PF13241.6 KFR09168.1 - 0.12 12.9 2.3 0.33 11.4 0.2 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KFR09168.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase YjeF_N PF03853.15 KFR09168.1 - 0.17 11.8 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus Attractin PF08037.11 KFR09168.1 - 1 9.4 5.2 0.51 10.4 2.1 2.1 2 0 0 2 2 1 0 Attractin family zf-RING_2 PF13639.6 KFR09168.1 - 3.8 7.9 12.6 0.39 11.1 7.3 2.2 2 0 0 2 2 1 0 Ring finger domain TPMT PF05724.11 KFR09169.1 - 4.3e-72 242.3 0.0 5.3e-72 242.0 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 KFR09169.1 - 0.01 16.5 0.0 0.1 13.3 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KFR09169.1 - 0.024 15.3 0.0 0.093 13.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain NHL PF01436.21 KFR09170.1 - 2.1e-24 84.3 4.6 0.00017 21.5 0.0 6.4 6 0 0 6 6 6 6 NHL repeat SGL PF08450.12 KFR09170.1 - 0.066 12.8 0.1 0.64 9.6 0.1 2.6 1 1 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Kinesin PF00225.23 KFR09171.1 - 2.2e-106 355.5 0.3 3.9e-106 354.7 0.3 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 KFR09171.1 - 5.6e-30 105.0 0.0 2.5e-29 102.9 0.0 2.2 1 1 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 KFR09171.1 - 2e-24 86.7 22.9 9.4e-20 71.5 1.8 4.3 4 1 1 5 5 5 2 Kinesin-associated CAP_GLY PF01302.25 KFR09171.1 - 1.4e-23 82.6 2.3 5e-23 80.9 2.3 2.0 2 0 0 2 2 2 1 CAP-Gly domain Microtub_bd PF16796.5 KFR09171.1 - 2.8e-21 76.0 0.0 9.1e-21 74.4 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 KFR09171.1 - 2.9e-16 59.6 0.0 1e-15 57.9 0.0 2.1 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.26 KFR09171.1 - 0.00015 22.1 0.1 0.0021 18.4 0.0 2.5 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KFR09171.1 - 0.0076 16.5 0.0 0.027 14.8 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Dynamin_N PF00350.23 KFR09171.1 - 0.014 15.4 1.5 0.34 11.0 0.0 3.5 3 0 0 3 3 3 0 Dynamin family KMP11 PF03037.16 KFR09171.1 - 0.17 12.7 7.4 0.26 12.1 1.4 2.9 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 Fib_alpha PF08702.10 KFR09171.1 - 8.6 6.5 15.9 11 6.2 2.0 4.5 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family SIR2 PF02146.17 KFR09173.1 - 2.3e-49 167.7 0.0 3.7e-49 167.0 0.0 1.3 1 1 0 1 1 1 1 Sir2 family PNTB PF02233.16 KFR09173.1 - 0.00021 20.4 0.1 0.0034 16.4 0.0 2.0 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit TPP_enzyme_M PF00205.22 KFR09173.1 - 0.12 12.1 0.0 17 5.1 0.0 2.6 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain CLTH PF10607.9 KFR09174.1 - 4.5e-48 162.9 0.0 6.5e-48 162.4 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 KFR09174.1 - 1.9e-25 89.3 0.2 4e-25 88.3 0.2 1.6 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 KFR09174.1 - 1.3e-06 28.1 0.0 3e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 LisH zf-RING_2 PF13639.6 KFR09176.1 - 9e-06 25.9 12.7 9e-06 25.9 12.7 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KFR09176.1 - 0.00016 21.5 13.2 0.00016 21.5 13.2 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFR09176.1 - 0.0041 17.1 10.2 0.015 15.3 10.2 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFR09176.1 - 0.01 15.7 13.2 0.026 14.4 13.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4462 PF14692.6 KFR09177.1 - 0.12 11.8 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) JmjC PF02373.22 KFR09179.1 - 2.4e-28 98.8 0.3 1.5e-27 96.3 0.2 2.4 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.21 KFR09179.1 - 4.9e-13 49.6 0.0 1.8e-12 47.8 0.0 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 KFR09179.1 - 7.7e-13 48.2 0.0 3e-12 46.3 0.1 2.0 2 0 0 2 2 2 1 jmjN domain zf-C5HC2 PF02928.16 KFR09179.1 - 6.3e-08 32.9 9.5 1e-07 32.3 7.1 2.5 2 0 0 2 2 2 1 C5HC2 zinc finger zf-C3HC4_2 PF13923.6 KFR09179.1 - 6.9 6.6 7.9 20 5.1 7.9 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Dysbindin PF04440.16 KFR09180.1 - 3.4e-69 231.6 9.1 7.8e-69 230.5 9.1 1.6 1 0 0 1 1 1 1 Dysbindin (Dystrobrevin binding protein 1) AIP3 PF03915.13 KFR09180.1 - 0.81 8.7 13.9 0.11 11.5 9.3 1.7 2 0 0 2 2 2 0 Actin interacting protein 3 FERM_M PF00373.18 KFR09182.1 - 2.1e-17 63.6 2.1 4.4e-17 62.6 2.1 1.5 1 0 0 1 1 1 1 FERM central domain zf-C3HC4_3 PF13920.6 KFR09182.1 - 6.4e-11 41.9 20.5 1.7e-10 40.6 20.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FERM_N PF09379.10 KFR09182.1 - 3.1e-09 36.7 0.0 6.7e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 FERM N-terminal domain FERM_C PF09380.10 KFR09182.1 - 1.7e-05 25.1 0.0 6.8e-05 23.2 0.0 2.0 2 1 0 2 2 2 1 FERM C-terminal PH-like domain Prok-RING_4 PF14447.6 KFR09182.1 - 0.0037 17.1 21.4 0.011 15.6 21.4 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Rab_eff_C PF04698.12 KFR09182.1 - 3.8 5.7 6.0 0.27 9.5 0.4 1.7 2 0 0 2 2 2 0 Rab effector MyRIP/melanophilin C-terminus IMPDH PF00478.25 KFR09183.1 - 1.2e-75 254.6 5.8 3.9e-75 253.0 5.8 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KFR09183.1 - 6.7e-05 22.1 0.6 0.00011 21.4 0.6 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase AXH PF08517.12 KFR09184.1 - 3.4e-42 143.6 0.1 6.5e-42 142.7 0.1 1.5 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) ATXN-1_C PF12547.8 KFR09184.1 - 2.3e-21 75.9 2.3 2.3e-21 75.9 2.3 3.7 3 1 0 3 3 3 1 Capicua transcriptional repressor modulator DUF759 PF05537.11 KFR09185.1 - 0.35 9.7 0.0 0.43 9.4 0.0 1.0 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) RDD PF06271.12 KFR09186.1 - 3.8e-12 46.6 5.1 1e-10 42.0 5.1 2.0 1 1 0 1 1 1 1 RDD family Trnau1ap PF17654.1 KFR09187.1 - 4.6e-36 123.8 16.6 7.5e-36 123.1 16.6 1.3 1 0 0 1 1 1 1 Selenocysteine tRNA 1 associated proteins RRM_1 PF00076.22 KFR09187.1 - 5.6e-11 42.1 0.0 9.1e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_assoc PF14363.6 KFR09187.1 - 0.19 12.1 1.7 11 6.5 0.0 2.2 2 0 0 2 2 2 0 Domain associated at C-terminal with AAA WD40 PF00400.32 KFR09188.1 - 3.9e-23 81.3 6.3 1.8e-05 25.4 0.4 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR09188.1 - 6.3e-08 32.8 2.1 0.022 15.0 0.0 4.9 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFR09188.1 - 8.4e-06 25.8 0.5 0.12 12.3 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFR09188.1 - 4.3e-05 22.6 4.4 0.0083 15.1 0.5 2.8 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 KFR09188.1 - 9.5e-05 22.4 0.3 0.2 11.7 0.1 3.2 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 KFR09188.1 - 0.0047 15.6 3.5 0.32 9.6 0.2 3.4 2 1 2 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KFR09188.1 - 0.027 13.8 2.7 0.48 9.7 0.0 2.5 1 1 1 2 2 2 0 WD40-like domain RNA_pol_Rpc4 PF05132.14 KFR09188.1 - 2.7 8.4 7.0 10 6.5 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 Tmemb_14 PF03647.13 KFR09189.1 - 6.2e-30 103.8 10.5 7e-30 103.6 10.5 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C CytB6-F_Fe-S PF08802.10 KFR09189.1 - 0.28 11.2 4.5 4 7.5 0.2 2.9 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit GFO_IDH_MocA_C PF02894.17 KFR09190.1 - 0.032 14.2 0.2 0.07 13.1 0.2 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain RabGAP-TBC PF00566.18 KFR09191.1 - 3.1e-05 23.7 6.8 0.00067 19.4 4.7 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DrrA_P4M PF14860.6 KFR09191.1 - 0.053 13.4 0.1 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain RPEL PF02755.15 KFR09192.1 - 2.1e-32 109.9 29.0 2.3e-09 36.6 2.9 4.6 4 0 0 4 4 4 4 RPEL repeat Endothelin PF00322.17 KFR09193.1 - 0.0031 17.1 2.1 0.0062 16.1 2.1 1.4 1 0 0 1 1 1 1 Endothelin family zf-C2H2 PF00096.26 KFR09194.1 - 3.1e-18 65.1 41.1 0.00017 21.9 1.6 6.1 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFR09194.1 - 2.2e-09 37.3 11.0 9.7e-07 28.9 0.6 5.6 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFR09194.1 - 2.3e-07 31.0 35.5 0.042 14.7 1.8 6.1 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFR09194.1 - 4e-06 27.0 41.1 0.014 15.7 1.4 5.8 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFR09194.1 - 0.00097 18.8 5.8 0.00097 18.8 5.8 5.8 5 0 0 5 5 5 3 C2H2-type zinc-finger domain NOA36 PF06524.12 KFR09194.1 - 0.006 16.0 25.0 0.016 14.5 1.6 3.2 3 0 0 3 3 3 2 NOA36 protein zf-met PF12874.7 KFR09194.1 - 0.41 11.1 38.5 1.5 9.3 0.5 5.5 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Far-17a_AIG1 PF04750.14 KFR09195.1 - 1e-58 198.0 16.2 1.2e-58 197.8 16.2 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Tmemb_170 PF10190.9 KFR09196.1 - 7.5e-36 122.7 12.3 8.2e-36 122.6 12.3 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 Gly_kinase PF02595.15 KFR09196.1 - 0.0038 16.3 0.1 0.0041 16.2 0.1 1.0 1 0 0 1 1 1 1 Glycerate kinase family CAS_C PF12026.8 KFR09197.1 - 9.6e-83 277.4 6.6 2.4e-82 276.1 6.6 1.6 1 0 0 1 1 1 1 Crk-Associated Substrate C-terminal domain Serine_rich PF08824.10 KFR09197.1 - 8.7e-58 194.8 3.5 8.7e-58 194.8 3.5 2.8 3 0 0 3 3 3 1 Serine rich protein interaction domain SH3_9 PF14604.6 KFR09197.1 - 2.1e-13 49.9 0.0 3.9e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFR09197.1 - 3.3e-11 42.6 0.0 5.8e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFR09197.1 - 4.2e-11 42.4 0.0 7.6e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain ELO PF01151.18 KFR09198.1 - 2.5e-59 200.8 23.3 2.8e-59 200.7 23.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family SYCP2_ARLD PF18581.1 KFR09199.1 - 4.1e-70 235.2 5.5 4.1e-70 235.2 5.5 2.2 2 0 0 2 2 2 1 Synaptonemal complex 2 armadillo-repeat-like domain SYCP2_SLD PF18584.1 KFR09199.1 - 8e-46 154.9 0.3 1.8e-45 153.7 0.3 1.7 1 0 0 1 1 1 1 Synaptonemal complex 2 Spt16M-like domain EF-hand_10 PF14788.6 KFR09199.1 - 0.033 14.1 0.5 0.11 12.4 0.5 1.9 1 0 0 1 1 1 0 EF hand GCM PF03615.15 KFR09200.1 - 3.7e-72 240.7 1.3 3.7e-72 240.7 1.3 1.6 2 0 0 2 2 2 1 GCM motif protein Pkinase PF00069.25 KFR09201.1 - 1.4e-75 254.1 0.0 1.8e-75 253.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR09201.1 - 1.8e-35 122.5 0.2 9.2e-35 120.2 0.2 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Tmemb_14 PF03647.13 KFR09202.1 - 9.2e-18 64.8 2.5 1e-17 64.6 2.5 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF308 PF03729.13 KFR09202.1 - 0.046 14.1 0.2 0.046 14.1 0.2 1.7 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) ETRAMP PF09716.10 KFR09202.1 - 1.4 9.0 4.9 7.4 6.7 0.4 2.8 1 1 2 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) OFCC1 PF15680.5 KFR09203.1 - 8.3e-60 200.1 3.2 1.3e-59 199.5 3.2 1.3 1 0 0 1 1 1 1 Orofacial cleft 1 candidate gene 1 protein DUF3674 PF12426.8 KFR09203.1 - 0.079 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA dependent RNA polymerase DUF4193 PF13834.6 KFR09203.1 - 0.4 11.2 2.5 2.7 8.5 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4193) UAA PF08449.11 KFR09204.1 - 5.5e-96 321.3 24.1 6.6e-96 321.1 24.1 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KFR09204.1 - 0.0028 17.8 30.7 0.0056 16.9 16.1 2.6 2 1 1 3 3 3 2 EamA-like transporter family GST_C PF00043.25 KFR09205.1 - 2.5e-08 34.0 0.3 6.2e-08 32.7 0.1 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFR09205.1 - 3.5e-05 23.9 0.1 5.5e-05 23.3 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFR09205.1 - 5.8e-05 23.0 0.0 0.00013 21.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Muted PF14942.6 KFR09206.1 - 7.8e-43 146.3 20.6 8.6e-43 146.2 20.6 1.0 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein Hydrolase_4 PF12146.8 KFR09206.1 - 0.021 14.1 0.2 0.027 13.7 0.2 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF148 PF02520.17 KFR09206.1 - 0.024 14.7 9.3 0.1 12.7 5.1 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF148 YkyA PF10368.9 KFR09206.1 - 0.039 13.6 15.4 0.055 13.1 15.4 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein FliD_C PF07195.12 KFR09206.1 - 0.1 12.0 6.1 0.21 11.0 6.1 1.7 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF802 PF05650.11 KFR09206.1 - 0.22 12.0 1.5 0.23 11.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF802) T3SSipB PF16535.5 KFR09206.1 - 0.34 11.4 6.6 2.6 8.5 2.8 2.1 1 1 1 2 2 2 0 Type III cell invasion protein SipB EcsC PF12787.7 KFR09206.1 - 0.45 10.1 8.8 0.13 11.9 0.9 1.9 1 1 1 2 2 2 0 EcsC protein family TMPIT PF07851.13 KFR09206.1 - 1.1 8.5 8.7 1.2 8.3 8.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein AAA_11 PF13086.6 KFR09206.1 - 1.2 8.8 9.6 1.4 8.7 9.6 1.0 1 0 0 1 1 1 0 AAA domain FUSC PF04632.12 KFR09206.1 - 2.8 6.4 4.3 3 6.3 4.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 KFR09206.1 - 4.8 6.7 10.3 5.4 6.5 10.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Thioredoxin PF00085.20 KFR09207.1 - 2.6e-82 271.5 0.1 3.8e-29 100.7 0.0 3.0 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_2 PF13098.6 KFR09207.1 - 5.2e-13 49.4 0.9 0.0067 16.9 0.1 3.6 3 1 0 3 3 3 3 Thioredoxin-like domain OST3_OST6 PF04756.13 KFR09207.1 - 6.2e-13 48.7 0.1 0.0041 16.5 0.0 3.1 3 0 0 3 3 3 3 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KFR09207.1 - 1.8e-08 34.6 0.3 0.91 9.9 0.0 5.2 3 3 3 6 6 6 3 Thioredoxin-like HyaE PF07449.11 KFR09207.1 - 9.7e-07 28.7 0.0 0.015 15.3 0.0 3.2 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE TraF PF13728.6 KFR09207.1 - 0.00023 21.1 9.7 0.43 10.4 0.0 4.4 3 2 2 5 5 5 3 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 KFR09207.1 - 0.00089 19.4 3.3 7.6 6.8 0.1 3.6 3 1 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 KFR09207.1 - 0.00095 19.1 1.0 1.2 9.1 0.0 2.8 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_9 PF14595.6 KFR09207.1 - 0.0097 15.7 0.1 3.9 7.3 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Ribosomal_L40e PF01020.17 KFR09207.1 - 0.46 10.4 3.7 23 4.9 0.4 3.5 3 0 0 3 3 3 0 Ribosomal L40e family Mu-like_Com PF10122.9 KFR09207.1 - 1.8 8.1 5.7 6.1 6.4 1.1 3.1 3 0 0 3 3 3 0 Mu-like prophage protein Com TGFb_propeptide PF00688.18 KFR09208.1 - 4.4e-61 206.8 0.1 6.5e-61 206.2 0.1 1.3 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 KFR09208.1 - 8.5e-39 132.7 0.9 2.1e-38 131.5 0.9 1.7 1 0 0 1 1 1 1 Transforming growth factor beta like domain Plectin PF00681.20 KFR09209.1 - 1.4e-129 421.7 8.4 1.9e-16 59.6 0.1 14.4 12 2 2 14 14 14 11 Plectin repeat Spectrin_like PF18373.1 KFR09209.1 - 4.9e-32 109.8 2.1 4.9e-32 109.8 2.1 6.1 5 1 0 5 5 5 1 Spectrin like domain SH3_10 PF17902.1 KFR09209.1 - 3.6e-19 68.6 0.0 1.4e-18 66.7 0.0 2.1 1 0 0 1 1 1 1 SH3 domain SOGA PF11365.8 KFR09209.1 - 0.0026 18.9 9.4 0.0026 18.9 9.4 13.6 6 1 5 13 13 13 4 Protein SOGA RIO1 PF01163.22 KFR09210.1 - 2.9e-76 255.3 0.5 2.9e-76 255.3 0.5 2.0 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KFR09210.1 - 0.0083 16.1 0.0 0.077 12.9 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family TRAP_alpha PF03896.16 KFR09211.1 - 2.3e-111 371.6 1.3 2.6e-111 371.4 1.3 1.0 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit zf-C2H2 PF00096.26 KFR09212.1 - 2.5e-43 144.2 122.5 7.9e-05 22.9 2.5 16.2 16 0 0 16 16 16 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR09212.1 - 1.8e-38 127.9 116.9 0.00045 20.8 1.1 16.0 16 0 0 16 16 16 15 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFR09212.1 - 5.7e-25 86.6 115.9 5e-08 33.0 1.1 19.3 20 0 0 20 20 20 7 Zinc-finger double domain zf-met PF12874.7 KFR09212.1 - 8.9e-12 45.0 75.1 0.012 15.9 0.4 13.1 13 0 0 13 13 13 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFR09212.1 - 7.8e-09 35.6 53.0 0.064 13.6 1.5 12.9 14 0 0 14 14 14 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFR09212.1 - 1.8e-08 34.2 98.6 4.9e-06 26.4 0.2 15.0 17 0 0 17 17 17 6 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFR09212.1 - 2.4e-07 30.4 0.0 2.4e-07 30.4 0.0 11.5 12 0 0 12 12 12 5 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KFR09212.1 - 0.0034 17.6 5.1 0.0034 17.6 5.1 9.4 7 4 3 10 10 10 5 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 KFR09212.1 - 0.0074 16.6 1.8 0.0074 16.6 1.8 6.4 7 0 0 7 7 7 3 C2H2-type zinc ribbon E1_DerP2_DerF2 PF02221.15 KFR09214.1 - 8.6e-08 32.7 0.4 1.3e-07 32.1 0.4 1.4 1 1 0 1 1 1 1 ML domain DUF3324 PF11797.8 KFR09214.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminal (DUF3324) Transglut_N PF00868.20 KFR09215.1 - 1.2e-36 125.7 0.2 2.1e-34 118.4 0.0 3.2 3 0 0 3 3 3 1 Transglutaminase family Transglut_C PF00927.22 KFR09215.1 - 2.2e-35 121.0 0.3 2e-16 60.1 0.0 2.5 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 KFR09215.1 - 5.2e-17 62.3 0.2 1.2e-16 61.2 0.2 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF11 PF01345.18 KFR09215.1 - 0.02 15.2 0.4 1.7 9.0 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function DUF11 TssD PF17642.1 KFR09215.1 - 0.079 12.8 0.1 0.21 11.4 0.1 1.7 1 0 0 1 1 1 0 Hemolysin coregulated protein Hcp (TssD) NRN1 PF15056.6 KFR09218.1 - 2.2e-23 82.2 0.5 2.6e-23 81.9 0.5 1.1 1 0 0 1 1 1 1 Neuritin protein family tRNA-synt_2d PF01409.20 KFR09220.1 - 8.9e-49 166.2 2.2 3.3e-30 105.4 0.2 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KFR09220.1 - 1.4e-21 76.7 0.0 5.4e-21 74.8 0.0 2.1 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.20 KFR09220.1 - 0.0074 15.4 0.1 1.2 8.1 0.1 2.6 3 0 0 3 3 3 2 tRNA synthetases class II (D, K and N) YdjM PF04307.14 KFR09220.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase Complex1_LYR PF05347.15 KFR09221.1 - 1.5e-11 44.2 1.7 1.6e-11 44.1 1.7 1.0 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFR09221.1 - 0.0002 22.1 0.6 0.0002 22.0 0.6 1.0 1 0 0 1 1 1 1 Complex1_LYR-like Noc2 PF03715.13 KFR09221.1 - 0.075 12.3 0.3 0.075 12.3 0.3 1.0 1 0 0 1 1 1 0 Noc2p family Ribonuc_P_40 PF08584.11 KFR09222.1 - 1.4e-94 316.6 0.0 1.5e-94 316.4 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit ECH_1 PF00378.20 KFR09224.1 - 1.5e-32 112.9 0.0 2.4e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Chromo PF00385.24 KFR09224.1 - 1.7e-18 66.2 3.7 4.4e-18 64.9 3.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ECH_2 PF16113.5 KFR09224.1 - 1.9e-16 60.5 0.8 9.7e-16 58.2 0.0 2.0 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Mtf2_C PF14061.6 KFR09224.1 - 0.012 15.8 0.2 0.023 14.9 0.2 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Tudor-knot PF11717.8 KFR09224.1 - 5.2 7.0 8.5 0.28 11.1 0.8 2.7 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain ECH_1 PF00378.20 KFR09225.1 - 8.7e-43 146.4 0.0 1.3e-42 145.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ACBP PF00887.19 KFR09225.1 - 4.9e-29 100.4 0.4 9.4e-29 99.5 0.4 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein ECH_2 PF16113.5 KFR09225.1 - 8.2e-19 68.3 0.0 2.5e-18 66.7 0.0 1.7 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase TPR_21 PF09976.9 KFR09225.1 - 0.045 13.4 1.6 4.7 6.9 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain NYN PF01936.18 KFR09225.1 - 0.067 13.7 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 NYN domain Pkinase PF00069.25 KFR09226.1 - 6.5e-49 166.7 0.7 6.5e-49 166.7 0.7 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR09226.1 - 9.6e-23 80.8 0.1 3e-22 79.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KFR09226.1 - 0.0012 18.0 0.3 0.002 17.2 0.3 1.4 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Sugar_tr PF00083.24 KFR09227.1 - 1.1e-23 83.8 19.8 1.5e-23 83.4 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFR09227.1 - 1.1e-17 64.1 19.9 3.4e-15 55.8 23.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PAC4 PF16093.5 KFR09228.1 - 0.0037 17.4 0.1 0.0058 16.8 0.1 1.4 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 DUF3974 PF13120.6 KFR09228.1 - 0.049 13.7 0.1 0.053 13.6 0.1 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3974) Tubulin PF00091.25 KFR09229.1 - 1.5e-59 201.5 0.0 2.2e-59 201.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFR09229.1 - 5e-25 88.1 0.8 4.7e-20 72.0 0.1 2.3 1 1 1 2 2 2 2 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFR09229.1 - 0.017 14.8 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 KFR09229.1 - 0.018 14.2 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 Tubulin like Tubulin PF00091.25 KFR09231.1 - 1.6e-59 201.4 0.0 2.6e-59 200.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFR09231.1 - 8.6e-44 148.7 0.1 1.4e-43 148.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 KFR09231.1 - 0.017 14.3 0.0 0.037 13.2 0.0 1.5 1 0 0 1 1 1 0 Tubulin like Tubulin_3 PF14881.6 KFR09231.1 - 0.019 14.7 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Abhydrolase_1 PF00561.20 KFR09233.1 - 9.6e-23 81.1 0.0 6e-16 58.9 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFR09233.1 - 8.7e-14 51.4 0.0 1.8e-08 34.0 0.0 2.1 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFR09233.1 - 4.4e-10 40.5 0.0 6.1e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KFR09233.1 - 0.00021 20.9 0.0 0.014 14.9 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.13 KFR09233.1 - 0.0017 18.1 0.1 0.0099 15.6 0.0 2.3 2 1 0 2 2 2 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 KFR09233.1 - 0.0029 17.6 0.0 0.0042 17.0 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 KFR09233.1 - 0.0029 17.1 0.0 0.028 13.9 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KFR09233.1 - 0.01 15.7 0.0 1 9.1 0.1 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.20 KFR09233.1 - 0.039 13.6 0.3 0.26 10.9 0.0 2.1 1 1 1 3 3 3 0 Putative esterase Abhydrolase_4 PF08386.10 KFR09233.1 - 0.15 12.2 0.0 0.34 11.0 0.0 1.6 2 0 0 2 2 2 0 TAP-like protein LIP PF03583.14 KFR09233.1 - 0.16 11.2 0.0 14 4.9 0.0 2.2 2 0 0 2 2 2 0 Secretory lipase Pkinase_Tyr PF07714.17 KFR09234.1 - 7.3e-51 172.9 0.1 1e-50 172.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR09234.1 - 1.8e-50 171.8 0.1 2.7e-50 171.2 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Death PF00531.22 KFR09234.1 - 2.8e-20 72.3 0.9 2.8e-19 69.0 0.3 2.7 2 0 0 2 2 2 1 Death domain RHIM PF12721.7 KFR09234.1 - 7e-08 32.8 3.7 7e-08 32.8 3.7 2.3 2 0 0 2 2 2 1 RIP homotypic interaction motif RIO1 PF01163.22 KFR09234.1 - 0.0026 17.4 0.1 0.0049 16.5 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KFR09234.1 - 0.0082 15.5 0.0 0.023 14.0 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFR09234.1 - 0.057 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFR09234.1 - 0.13 12.2 0.0 0.43 10.4 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Flavodoxin_2 PF02525.17 KFR09235.1 - 5.9e-51 173.0 0.0 6.9e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 KFR09235.1 - 5.8e-12 45.6 0.0 1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.7 KFR09235.1 - 0.0091 15.7 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin DSPc PF00782.20 KFR09236.1 - 3.4e-26 91.6 0.5 1.3e-24 86.5 0.1 2.3 1 1 1 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFR09236.1 - 0.00057 19.5 0.4 0.0008 19.0 0.1 1.5 1 1 1 2 2 2 1 Protein-tyrosine phosphatase Complex1_LYR PF05347.15 KFR09236.1 - 0.0054 16.8 1.2 0.017 15.2 1.2 1.9 1 1 0 1 1 1 1 Complex 1 protein (LYR family) IRF-3 PF10401.9 KFR09237.1 - 3.4e-65 219.2 0.1 4.5e-65 218.8 0.1 1.1 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.17 KFR09237.1 - 1.9e-42 143.8 0.2 2.9e-42 143.2 0.2 1.3 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor MH2 PF03166.14 KFR09237.1 - 0.005 17.1 0.0 0.0076 16.5 0.0 1.2 1 0 0 1 1 1 1 MH2 domain Sec5 PF15469.6 KFR09238.1 - 5.9e-55 186.0 0.8 1.7e-54 184.5 0.1 2.2 2 0 0 2 2 2 1 Exocyst complex component Sec5 TIG PF01833.24 KFR09238.1 - 1.7e-08 34.4 0.6 3.4e-08 33.5 0.6 1.5 1 0 0 1 1 1 1 IPT/TIG domain SAM_2 PF07647.17 KFR09238.1 - 0.016 15.3 0.1 0.066 13.3 0.1 2.0 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Forkhead PF00250.18 KFR09239.1 - 1.7e-38 130.7 0.0 2e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 Forkhead domain GDP_Man_Dehyd PF16363.5 KFR09240.1 - 3.1e-143 477.2 0.0 3.4e-143 477.0 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFR09240.1 - 2.5e-69 233.4 0.0 3.1e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFR09240.1 - 0.00026 20.2 0.0 0.00036 19.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain MgsA_C PF12002.8 KFR09241.1 - 5.3e-59 198.9 0.0 1.8e-58 197.2 0.0 1.8 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KFR09241.1 - 1.1e-25 89.8 0.0 2.5e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KFR09241.1 - 2.8e-09 37.5 0.4 5.2e-09 36.6 0.4 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFR09241.1 - 5.5e-05 23.0 0.2 0.00014 21.6 0.2 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 KFR09241.1 - 0.0043 16.8 0.0 0.012 15.3 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.6 KFR09241.1 - 0.019 15.0 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta2 PF13177.6 KFR09241.1 - 0.084 12.7 0.6 0.14 11.9 0.2 1.5 2 0 0 2 2 2 0 DNA polymerase III, delta subunit ResIII PF04851.15 KFR09241.1 - 0.099 12.6 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Serpin PF00079.20 KFR09242.1 - 7.7e-131 436.8 0.1 8.7e-131 436.6 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFR09243.1 - 9.9e-133 443.0 0.6 1.1e-132 442.8 0.6 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Flu_B_NS1 PF02942.14 KFR09243.1 - 0.093 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) Serpin PF00079.20 KFR09244.1 - 6.4e-133 443.6 4.8 7.2e-133 443.5 4.8 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) JHBP PF06585.11 KFR09244.1 - 0.04 13.1 0.0 0.43 9.7 0.0 2.1 2 0 0 2 2 2 0 Haemolymph juvenile hormone binding protein (JHBP) Serpin PF00079.20 KFR09245.1 - 1.2e-127 426.3 8.0 1.3e-127 426.1 8.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFR09246.1 - 2.8e-130 435.0 1.4 3.1e-130 434.8 1.4 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFR09247.1 - 4.3e-80 269.8 0.2 4.7e-80 269.7 0.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Sec-ASP3 PF15432.6 KFR09247.1 - 0.0055 16.8 0.1 0.013 15.7 0.0 1.6 2 0 0 2 2 2 1 Accessory Sec secretory system ASP3 EF1_GNE PF00736.19 KFR09247.1 - 0.059 13.5 0.2 0.12 12.6 0.2 1.7 1 1 0 1 1 1 0 EF-1 guanine nucleotide exchange domain DUF3161 PF11362.8 KFR09247.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) Serpin PF00079.20 KFR09248.1 - 1.6e-79 267.9 0.4 1.8e-79 267.7 0.4 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Sec-ASP3 PF15432.6 KFR09248.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Accessory Sec secretory system ASP3 Serpin PF00079.20 KFR09249.1 - 3.8e-78 263.4 0.6 4.2e-78 263.2 0.6 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Sec-ASP3 PF15432.6 KFR09249.1 - 0.076 13.2 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Accessory Sec secretory system ASP3 Serpin PF00079.20 KFR09250.1 - 1.8e-125 419.1 0.5 2e-125 419.0 0.5 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFR09251.1 - 2.1e-78 264.2 0.0 2.3e-78 264.1 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFR09252.1 - 9.2e-122 406.9 4.2 1e-121 406.8 4.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFR09253.1 - 1.4e-99 333.9 6.4 1.6e-99 333.7 6.4 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Toprim_Crpt PF13342.6 KFR09253.1 - 0.041 13.9 1.6 0.72 9.9 0.1 3.1 3 0 0 3 3 3 0 C-terminal repeat of topoisomerase AAA PF00004.29 KFR09254.1 - 2.3e-31 109.0 0.0 3.8e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KFR09254.1 - 2.6e-06 26.9 0.0 3.4e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KFR09254.1 - 2.7e-06 27.2 0.0 3.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KFR09254.1 - 3.1e-06 27.5 0.1 0.0006 20.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFR09254.1 - 3.1e-06 27.7 0.0 0.00086 19.7 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KFR09254.1 - 1.2e-05 25.1 0.0 1.5e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KFR09254.1 - 1.6e-05 24.9 0.0 2.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFR09254.1 - 2e-05 24.6 0.0 5e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KFR09254.1 - 5.4e-05 22.5 0.0 0.00011 21.5 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KFR09254.1 - 7.2e-05 23.3 0.0 0.00014 22.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KFR09254.1 - 0.00013 21.7 0.1 0.37 10.4 0.1 2.2 1 1 0 2 2 2 2 AAA domain AAA_2 PF07724.14 KFR09254.1 - 0.00028 21.0 0.0 0.00048 20.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KFR09254.1 - 0.0011 19.2 0.0 0.0016 18.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 KFR09254.1 - 0.0021 17.4 0.1 0.88 8.9 0.0 2.1 1 1 1 2 2 2 2 KaiC AAA_24 PF13479.6 KFR09254.1 - 0.0022 17.8 0.0 0.0037 17.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KFR09254.1 - 0.0027 18.1 0.0 0.004 17.5 0.0 1.4 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.12 KFR09254.1 - 0.0034 17.3 0.0 0.078 12.9 0.0 2.1 1 1 1 2 2 2 1 NACHT domain TniB PF05621.11 KFR09254.1 - 0.0035 16.8 0.0 1.7 8.0 0.0 2.2 1 1 0 2 2 2 1 Bacterial TniB protein AAA_7 PF12775.7 KFR09254.1 - 0.0045 16.5 0.0 0.012 15.1 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region PhoH PF02562.16 KFR09254.1 - 0.0068 15.9 0.1 0.018 14.5 0.0 1.6 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 KFR09254.1 - 0.0078 15.6 0.1 0.018 14.4 0.0 1.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KFR09254.1 - 0.012 15.3 0.0 0.051 13.3 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 KFR09254.1 - 0.023 14.0 0.0 0.6 9.3 0.0 2.3 1 1 1 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 KFR09254.1 - 0.028 14.4 0.0 1.7 8.5 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea MCM PF00493.23 KFR09254.1 - 0.029 13.5 0.0 0.05 12.7 0.0 1.4 2 0 0 2 2 2 0 MCM P-loop domain AAA_17 PF13207.6 KFR09254.1 - 0.036 14.5 0.0 0.077 13.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 KFR09254.1 - 0.04 13.6 0.0 0.073 12.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KFR09254.1 - 0.041 14.0 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase Torsin PF06309.11 KFR09254.1 - 0.045 13.9 0.0 0.083 13.0 0.0 1.5 1 1 0 1 1 1 0 Torsin Sigma54_activ_2 PF14532.6 KFR09254.1 - 0.054 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 KFR09254.1 - 0.056 13.4 0.0 0.087 12.8 0.0 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit KAP_NTPase PF07693.14 KFR09254.1 - 0.068 12.4 0.1 1.2 8.3 0.0 1.9 1 1 1 2 2 2 0 KAP family P-loop domain Viral_helicase1 PF01443.18 KFR09254.1 - 0.068 12.9 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.17 KFR09254.1 - 0.074 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KFR09254.1 - 0.08 13.2 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 KFR09254.1 - 0.098 11.5 0.0 0.098 11.5 0.0 1.1 1 0 0 1 1 1 0 AFG1-like ATPase ABC_tran PF00005.27 KFR09254.1 - 0.11 13.0 0.0 0.18 12.3 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Guanylate_kin PF00625.21 KFR09254.1 - 0.11 12.2 0.0 0.33 10.6 0.0 1.7 1 1 0 2 2 2 0 Guanylate kinase AAA_29 PF13555.6 KFR09254.1 - 0.13 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 KFR09254.1 - 0.15 11.8 0.6 12 5.5 0.1 2.1 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system EF-1_beta_acid PF10587.9 KFR09254.1 - 1.1 9.8 3.7 26 5.4 0.1 2.7 3 0 0 3 3 2 0 Eukaryotic elongation factor 1 beta central acidic region Vps4_C PF09336.10 KFR09255.1 - 3.5e-30 103.8 0.3 5.8e-30 103.1 0.3 1.4 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 KFR09255.1 - 5.7e-09 35.6 0.0 2.2e-08 33.8 0.0 1.9 2 0 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 KFR09255.1 - 0.00012 22.5 0.0 0.00038 20.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) adh_short PF00106.25 KFR09256.1 - 1.1e-53 181.6 0.0 1.4e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFR09256.1 - 2.4e-30 105.8 0.0 3.2e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFR09256.1 - 1.1e-13 51.5 0.0 1.6e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFR09256.1 - 0.0011 18.9 0.0 0.0026 17.7 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KFR09256.1 - 0.0017 18.6 0.1 0.0031 17.8 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 KFR09256.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Bcl-2 PF00452.19 KFR09257.1 - 9.4e-21 74.4 0.0 1.6e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family BH4 PF02180.17 KFR09257.1 - 1.8e-12 46.7 0.3 3.5e-12 45.8 0.3 1.5 1 0 0 1 1 1 1 Bcl-2 homology region 4 Bcl-2_3 PF15286.6 KFR09257.1 - 0.026 15.2 0.0 0.039 14.6 0.0 1.3 1 0 0 1 1 1 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like MARVEL PF01284.23 KFR09258.1 - 0.0022 18.0 3.5 0.0032 17.5 3.5 1.3 1 0 0 1 1 1 1 Membrane-associating domain zf-CCHC PF00098.23 KFR09260.1 - 3.1e-06 27.0 2.4 9.9e-06 25.4 2.4 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KFR09260.1 - 0.28 11.0 2.6 0.69 9.8 2.6 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 KFR09260.1 - 1.9 8.3 5.1 0.33 10.7 1.1 1.9 2 0 0 2 2 2 0 Zinc knuckle RANK_CRD_2 PF18278.1 KFR09261.1 - 1.7e-27 95.3 7.6 1.7e-27 95.3 7.6 2.7 2 0 0 2 2 2 1 Receptor activator of the NF-KB cysteine-rich repeat domain 2 TNFR_c6 PF00020.18 KFR09261.1 - 9.1e-15 54.8 43.3 6.5e-05 23.3 0.2 4.7 5 0 0 5 5 5 4 TNFR/NGFR cysteine-rich region HEAT PF02985.22 KFR09262.1 - 3.2e-16 58.0 0.8 0.011 16.0 0.0 6.7 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 KFR09262.1 - 1e-08 35.4 0.1 0.00058 20.2 0.0 3.8 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 KFR09262.1 - 0.00025 21.5 2.3 0.28 11.8 0.0 4.7 5 0 0 5 5 5 1 HEAT-like repeat Cnd1 PF12717.7 KFR09262.1 - 0.049 13.7 0.4 3 7.9 0.0 2.9 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 KFR09262.1 - 0.088 12.7 1.8 0.79 9.6 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) Nuc_H_symport PF03825.16 KFR09262.1 - 0.12 11.3 0.1 5.3 5.9 0.0 2.3 2 0 0 2 2 2 0 Nucleoside H+ symporter DUF4128 PF13554.6 KFR09262.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function TMF_TATA_bd PF12325.8 KFR09262.1 - 0.35 11.1 5.2 0.64 10.2 0.3 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4140 PF13600.6 KFR09262.1 - 0.37 11.3 1.4 31 5.1 0.0 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 KFR09262.1 - 1.2 8.9 5.6 1.6 8.6 0.2 2.6 2 0 0 2 2 2 0 Septum formation initiator PigN PF04987.14 KFR09263.1 - 7.2e-138 460.3 47.6 9.5e-138 459.9 47.6 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KFR09263.1 - 9.8e-16 58.3 0.3 6.8e-14 52.2 0.3 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KFR09263.1 - 2e-06 27.3 0.0 3.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KFR09263.1 - 0.00021 20.8 0.1 0.00041 19.9 0.0 1.5 2 0 0 2 2 2 1 Sulfatase zf-RING_5 PF14634.6 KFR09264.1 - 1.2e-07 31.6 11.6 1.2e-07 31.6 11.6 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFR09264.1 - 5e-07 29.5 12.7 9.4e-07 28.6 12.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFR09264.1 - 9.7e-07 29.0 13.1 2.2e-06 27.9 13.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFR09264.1 - 2.4e-05 24.3 10.7 4.9e-05 23.3 10.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 KFR09264.1 - 9.3e-05 22.1 4.2 0.073 12.8 0.1 2.6 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFR09264.1 - 0.00066 19.5 12.9 0.0014 18.4 12.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFR09264.1 - 0.0025 17.9 11.7 0.0025 17.9 11.7 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFR09264.1 - 0.0078 16.0 8.5 0.023 14.6 8.5 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 VMA21 PF09446.10 KFR09264.1 - 0.058 13.5 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 VMA21-like domain zf-RING_10 PF16685.5 KFR09264.1 - 0.072 13.2 8.6 0.13 12.4 8.6 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KFR09264.1 - 2.4 8.0 13.8 9.3 6.1 13.8 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Cadherin PF00028.17 KFR09265.1 - 4.6e-82 270.6 2.6 2.1e-18 66.6 0.0 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFR09265.1 - 5.2e-52 176.0 0.2 1.1e-51 175.0 0.2 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_3 PF16184.5 KFR09265.1 - 8.7e-07 28.9 4.5 0.35 10.9 0.0 4.9 5 0 0 5 5 5 2 Cadherin-like Cadherin_2 PF08266.12 KFR09265.1 - 1.2e-05 25.1 0.0 0.68 9.8 0.0 4.4 4 0 0 4 4 4 2 Cadherin-like Cadherin_4 PF17803.1 KFR09265.1 - 0.11 13.1 15.0 0.28 11.8 0.4 4.5 4 1 0 4 4 4 0 Bacterial cadherin-like domain Invasin_D3 PF09134.10 KFR09265.1 - 0.74 10.2 3.9 46 4.4 0.0 4.1 6 0 0 6 6 6 0 Invasin, domain 3 7tm_1 PF00001.21 KFR09266.1 - 5.2e-36 124.3 34.3 1.3e-34 119.7 34.3 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFR09266.1 - 5.3e-11 42.8 24.9 1.6e-10 41.2 17.0 2.5 1 1 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KFR09266.1 - 1.3e-10 41.1 33.8 2.6e-10 40.1 33.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFR09266.1 - 0.00094 18.9 24.6 0.00094 18.9 24.6 2.8 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx UPF0489 PF12640.7 KFR09267.1 - 5.7e-57 192.8 0.0 1.2e-56 191.8 0.0 1.6 1 0 0 1 1 1 1 UPF0489 domain Ribonucleas_3_3 PF14622.6 KFR09268.1 - 5.4e-44 149.4 0.7 4.7e-24 85.0 0.0 3.2 3 0 0 3 3 3 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KFR09268.1 - 1.1e-42 144.9 0.3 1.1e-20 74.2 0.0 3.2 2 0 0 2 2 2 2 Ribonuclease III domain dsrm PF00035.26 KFR09268.1 - 5.6e-15 55.8 0.0 2.1e-14 54.0 0.0 2.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif Cadherin PF00028.17 KFR09269.1 - 7.9e-77 253.8 9.6 4e-19 68.8 0.2 5.4 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFR09269.1 - 6.7e-59 198.4 0.7 1.4e-58 197.3 0.7 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_3 PF16184.5 KFR09269.1 - 3.2e-08 33.5 5.8 0.24 11.4 0.1 5.4 5 1 0 5 5 5 3 Cadherin-like Cadherin_4 PF17803.1 KFR09269.1 - 4.6e-05 24.0 19.1 0.016 15.8 1.0 5.0 4 0 0 4 4 4 2 Bacterial cadherin-like domain Cadherin_2 PF08266.12 KFR09269.1 - 6.3e-05 22.7 0.0 1.2 9.0 0.0 3.6 3 0 0 3 3 3 2 Cadherin-like ASFV_J13L PF05568.11 KFR09269.1 - 0.005 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 African swine fever virus J13L protein Stevor PF17410.2 KFR09269.1 - 0.041 13.4 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Invasin_D3 PF09134.10 KFR09269.1 - 0.053 13.8 5.5 28 5.1 0.1 4.8 4 1 0 4 4 4 0 Invasin, domain 3 Cadherin_pro PF08758.11 KFR09269.1 - 0.056 13.6 0.0 3.8 7.7 0.0 3.0 3 0 0 3 3 3 0 Cadherin prodomain like 7TM_GPCR_Srw PF10324.9 KFR09269.1 - 0.13 11.5 0.2 0.21 10.8 0.2 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Big_9 PF17963.1 KFR09269.1 - 1.1 10.0 19.0 0.14 12.9 0.7 4.7 5 0 0 5 5 5 0 Bacterial Ig domain Pentapeptide_4 PF13599.6 KFR09286.1 - 0.004 17.3 0.0 1.1 9.4 0.0 2.0 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) DUF2924 PF11149.8 KFR09286.1 - 0.62 10.4 3.9 3.2 8.1 3.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2924) ANF_receptor PF01094.28 KFR09289.1 - 3.5e-82 276.3 0.0 5e-82 275.8 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 KFR09289.1 - 3.5e-55 186.0 0.2 5.4e-55 185.3 0.2 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFR09289.1 - 8.6e-47 158.1 0.0 4.7e-46 155.7 0.0 2.3 3 0 0 3 3 3 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFR09289.1 - 1e-17 64.3 0.0 1.9e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.6 KFR09289.1 - 5.7e-09 36.1 0.0 1.4e-08 34.8 0.0 1.5 2 0 0 2 2 2 1 Periplasmic binding protein SIM_C PF06621.12 KFR09291.1 - 2.9e-111 372.2 17.0 4.3e-111 371.7 17.0 1.2 1 0 0 1 1 1 1 Single-minded protein C-terminus PAS_3 PF08447.12 KFR09291.1 - 2.3e-18 66.3 2.1 4.4e-11 42.9 0.0 3.2 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 KFR09291.1 - 3.5e-17 62.4 0.0 6.9e-12 45.4 0.0 2.8 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.6 KFR09291.1 - 4.7e-12 46.0 0.5 4.8e-06 26.7 0.1 2.8 3 0 0 3 3 3 2 PAS domain HLH PF00010.26 KFR09291.1 - 3.3e-06 26.9 0.9 5.4e-05 23.1 0.7 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 KFR09291.1 - 0.00076 19.7 0.0 0.017 15.3 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 KFR09291.1 - 0.0012 19.1 0.0 0.03 14.6 0.0 2.8 3 0 0 3 3 3 1 PAS fold SET PF00856.28 KFR09292.1 - 0.0002 21.8 0.0 0.0002 21.8 0.0 1.3 1 1 0 1 1 1 1 SET domain Cyclin_N PF00134.23 KFR09293.1 - 2.4e-14 53.2 3.7 7.9e-13 48.3 0.7 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KFR09293.1 - 5.9e-07 29.8 0.3 2.2e-06 28.0 0.3 2.0 1 1 0 1 1 1 1 Cyclin C-terminal domain TFIIB PF00382.19 KFR09293.1 - 0.007 16.4 0.1 0.11 12.6 0.0 2.2 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C PF02984.19 KFR09293.1 - 0.0081 16.2 0.7 0.065 13.3 0.1 2.5 2 1 1 3 3 3 1 Cyclin, C-terminal domain Rhodanese PF00581.20 KFR09294.1 - 5.2e-08 33.4 0.0 5.8e-08 33.2 0.0 1.0 1 0 0 1 1 1 1 Rhodanese-like domain UCH PF00443.29 KFR09295.1 - 6e-46 157.0 2.4 9.3e-46 156.4 2.4 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFR09295.1 - 7.8e-18 64.6 8.9 7.8e-18 64.6 8.9 2.7 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein THOC7 PF05615.13 KFR09295.1 - 1.4 9.2 8.5 0.057 13.7 0.8 2.5 3 0 0 3 3 3 0 Tho complex subunit 7 zf-4CXXC_R1 PF10497.9 KFR09295.1 - 4 7.7 14.2 0.082 13.1 3.8 2.9 2 1 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zinc_ribbon_9 PF14369.6 KFR09295.1 - 4.6 7.6 6.6 2.8 8.3 0.8 3.2 3 0 0 3 3 3 0 zinc-ribbon PNISR PF15996.5 KFR09296.1 - 3e-53 181.1 25.5 3e-53 181.1 25.5 5.8 2 2 2 4 4 4 1 Arginine/serine-rich protein PNISR Methyltransf_23 PF13489.6 KFR09297.1 - 2.2e-21 76.4 0.0 3.4e-21 75.8 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFR09297.1 - 8.2e-19 68.1 0.0 1.4e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFR09297.1 - 3.1e-15 56.7 0.0 4.8e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFR09297.1 - 1.7e-14 54.3 0.0 3.1e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFR09297.1 - 5.3e-13 49.0 0.0 7e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KFR09297.1 - 2.8e-08 33.4 0.0 3.9e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KFR09297.1 - 9.2e-07 28.5 0.0 1.3e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 KFR09297.1 - 3.7e-05 23.4 0.0 5.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 KFR09297.1 - 4.3e-05 23.0 0.0 6.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KFR09297.1 - 6.8e-05 22.5 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 KFR09297.1 - 0.00089 18.3 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.14 KFR09297.1 - 0.0026 17.2 0.0 0.0038 16.7 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_16 PF10294.9 KFR09297.1 - 0.0029 17.4 0.0 0.0049 16.6 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_PK PF05891.12 KFR09297.1 - 0.0078 15.7 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_32 PF13679.6 KFR09297.1 - 0.059 13.4 0.1 0.14 12.1 0.0 1.6 1 1 1 2 2 2 0 Methyltransferase domain GST_N_4 PF17172.4 KFR09298.1 - 1.3e-31 109.2 0.0 2.4e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KFR09298.1 - 3.2e-19 68.5 0.0 5.7e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KFR09298.1 - 1.3e-14 54.6 0.1 3.7e-14 53.1 0.0 1.7 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 KFR09298.1 - 4e-05 23.5 0.0 8.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFR09298.1 - 0.0023 18.3 0.0 0.037 14.4 0.0 2.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain LRR_4 PF12799.7 KFR09299.1 - 4.6e-09 36.4 16.1 0.0058 17.0 0.0 7.2 5 1 4 9 9 9 4 Leucine Rich repeats (2 copies) F-box PF00646.33 KFR09299.1 - 4e-08 32.9 0.4 4e-08 32.9 0.4 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KFR09299.1 - 6.6e-08 32.3 2.8 2.6e-07 30.4 2.8 2.2 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 KFR09299.1 - 0.00022 21.0 8.1 1.9 8.8 0.2 6.4 6 0 0 6 6 6 1 Leucine Rich repeat LRR_9 PF14580.6 KFR09299.1 - 0.00052 19.6 0.2 0.48 9.9 0.1 2.5 2 0 0 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KFR09299.1 - 0.0013 18.5 6.0 0.61 9.9 0.0 4.7 3 2 2 5 5 5 3 Leucine rich repeat F-box_4 PF15966.5 KFR09299.1 - 0.0024 17.8 0.1 0.007 16.2 0.1 1.8 1 0 0 1 1 1 1 F-box LRR_1 PF00560.33 KFR09299.1 - 0.0051 17.2 17.9 2.3 9.1 0.2 7.4 7 1 0 7 7 7 2 Leucine Rich Repeat Adeno_E3_CR2 PF02439.15 KFR09299.1 - 0.26 11.1 0.9 0.5 10.2 0.9 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Pou PF00157.17 KFR09300.1 - 4.8e-38 129.0 0.3 9.2e-38 128.1 0.3 1.5 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KFR09300.1 - 1e-19 70.1 0.3 2.4e-19 68.9 0.3 1.6 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 KFR09300.1 - 0.00014 22.1 0.0 0.023 15.1 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain Homeobox_KN PF05920.11 KFR09300.1 - 0.003 17.4 0.0 0.007 16.3 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain DUF521 PF04412.13 KFR09300.1 - 0.12 11.1 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) MMS22L_N PF14910.6 KFR09301.1 - 0 1266.5 25.1 0 1266.0 25.1 1.2 1 0 0 1 1 1 1 S-phase genomic integrity recombination mediator, N-terminal MMS22L_C PF14911.6 KFR09301.1 - 4.8e-145 483.4 4.5 4.8e-145 483.4 4.5 1.7 2 0 0 2 2 2 1 S-phase genomic integrity recombination mediator, C-terminal Kelch_1 PF01344.25 KFR09302.1 - 8.4e-37 124.5 15.6 6.6e-10 38.4 0.0 6.8 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KFR09302.1 - 3.7e-33 112.7 8.5 2.8e-06 27.4 0.0 7.4 4 2 2 6 6 6 5 Kelch motif BTB PF00651.31 KFR09302.1 - 6e-27 94.1 1.9 1.9e-26 92.5 0.3 2.4 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.6 KFR09302.1 - 2.2e-17 62.8 0.7 0.062 13.3 0.0 6.6 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KFR09302.1 - 5e-17 61.1 2.8 0.033 14.2 0.0 5.7 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 KFR09302.1 - 8.2e-17 61.0 4.1 0.0017 18.6 0.0 6.9 6 1 0 6 6 6 5 Galactose oxidase, central domain BACK PF07707.15 KFR09302.1 - 2.7e-16 59.5 1.7 7.1e-16 58.2 1.7 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 KFR09302.1 - 2.4e-14 53.0 3.1 0.12 12.4 0.1 6.5 6 0 0 6 6 6 4 Kelch motif UPF0240 PF06784.11 KFR09304.1 - 3.8e-36 124.8 0.1 4.2e-36 124.6 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0240) 7tm_1 PF00001.21 KFR09305.1 - 4.4e-50 170.4 23.7 6.7e-50 169.8 23.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR09305.1 - 4.7e-07 29.5 25.1 7.7e-07 28.8 25.1 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFR09305.1 - 0.0013 18.5 9.5 0.0013 18.5 9.5 3.0 3 0 0 3 3 3 1 Olfactory receptor DUF5527 PF17665.1 KFR09305.1 - 0.022 14.3 0.9 0.06 12.9 0.9 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5527) LIM PF00412.22 KFR09306.1 - 4.9e-48 161.2 68.5 1.4e-12 47.6 7.2 5.1 5 0 0 5 5 5 5 LIM domain E3_UFM1_ligase PF09743.9 KFR09307.1 - 1.7e-107 359.1 0.1 1.7e-107 359.1 0.1 2.2 3 0 0 3 3 3 1 E3 UFM1-protein ligase 1 Tn7_Tnp_TnsA_C PF08721.11 KFR09307.1 - 0.37 11.4 6.2 1.2 9.9 0.0 4.2 4 0 0 4 4 4 0 TnsA endonuclease C terminal Glyco_hydro_99 PF16317.5 KFR09308.1 - 1.2e-170 567.2 10.9 1.4e-170 567.0 10.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 99 DUF4434 PF14488.6 KFR09308.1 - 0.046 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) RVT_1 PF00078.27 KFR09312.1 - 0.034 13.6 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.17 KFR09313.1 - 1.8e-97 325.7 0.0 2.8e-97 325.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.19 KFR09313.1 - 7.6e-72 241.1 0.3 1.4e-71 240.2 0.3 1.5 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.25 KFR09313.1 - 4.9e-46 157.2 0.0 8.3e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 KFR09313.1 - 1.7e-29 102.0 8.1 1.9e-15 56.9 1.3 3.7 4 0 0 4 4 4 2 Fibronectin type III domain SAM_1 PF00536.30 KFR09313.1 - 3.1e-22 78.8 0.0 5.4e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFR09313.1 - 5e-21 74.6 0.0 9.6e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EphA2_TM PF14575.6 KFR09313.1 - 2.6e-20 73.1 0.0 6.3e-20 71.8 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Ephrin_rec_like PF07699.13 KFR09313.1 - 9.5e-06 25.3 10.4 9.5e-06 25.3 10.4 2.6 2 0 0 2 2 2 1 Putative ephrin-receptor like Pur_ac_phosph_N PF16656.5 KFR09313.1 - 0.00028 21.4 3.0 0.00061 20.3 0.7 2.6 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.5 KFR09313.1 - 0.0043 17.2 0.8 2.6 8.3 0.0 2.6 2 0 0 2 2 2 2 Fibronectin type III domain Tissue_fac PF01108.17 KFR09313.1 - 0.0045 16.8 0.2 0.43 10.4 0.0 2.6 2 0 0 2 2 2 1 Tissue factor DUF2318 PF10080.9 KFR09313.1 - 0.0095 16.0 1.9 0.034 14.3 1.9 1.9 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) Interfer-bind PF09294.10 KFR09313.1 - 0.01 16.1 0.3 0.17 12.2 0.1 2.7 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III DUF4998 PF16389.5 KFR09313.1 - 0.012 15.2 0.0 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function Haspin_kinase PF12330.8 KFR09313.1 - 0.013 14.5 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain SusE PF14292.6 KFR09313.1 - 0.044 14.0 0.1 9.8 6.5 0.1 2.6 2 0 0 2 2 2 0 SusE outer membrane protein Y_Y_Y PF07495.13 KFR09313.1 - 0.047 13.7 0.4 0.95 9.5 0.6 2.5 2 0 0 2 2 2 0 Y_Y_Y domain Kdo PF06293.14 KFR09313.1 - 0.085 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GPI-anchored PF10342.9 KFR09313.1 - 0.13 13.1 0.1 1.2 9.9 0.2 2.4 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PRIMA1 PF16101.5 KFR09313.1 - 1.7 8.7 5.1 11 6.1 0.0 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 EGF_MSP1_1 PF12946.7 KFR09313.1 - 2.7 8.1 6.6 0.38 10.9 1.7 2.1 2 0 0 2 2 2 0 MSP1 EGF domain 1 Gyro_capsid PF04162.12 KFR09317.1 - 0.034 12.6 0.4 0.036 12.6 0.4 1.0 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) Pkinase_Tyr PF07714.17 KFR09318.1 - 2.6e-59 200.6 0.0 4.3e-59 199.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFR09318.1 - 8.2e-55 186.0 0.0 2.3e-54 184.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 KFR09318.1 - 0.0053 16.7 0.3 0.014 15.4 0.0 1.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Lectin_N PF03954.14 KFR09318.1 - 3.3 7.5 7.5 0.15 11.8 0.7 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain CENP-H PF05837.12 KFR09318.1 - 8.7 6.8 15.8 2.7 8.4 11.0 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) BTB PF00651.31 KFR09319.1 - 3.8e-28 97.9 0.3 6.4e-28 97.2 0.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain bZIP_Maf PF03131.17 KFR09319.1 - 4.5e-13 49.5 2.5 1.1e-12 48.3 2.5 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 KFR09319.1 - 1.3e-09 38.0 6.7 2.4e-09 37.1 6.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFR09319.1 - 1.8e-05 24.7 7.5 3e-05 24.0 7.5 1.4 1 0 0 1 1 1 1 Basic region leucine zipper DUF3342 PF11822.8 KFR09319.1 - 0.039 14.1 0.0 0.15 12.3 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) Connexin PF00029.19 KFR09320.1 - 2.1e-89 299.3 0.1 2.3e-89 299.2 0.1 1.0 1 0 0 1 1 1 1 Connexin AAA_5 PF07728.14 KFR09321.1 - 9.4e-124 407.9 0.0 6.7e-25 87.7 0.0 8.8 7 1 1 8 8 8 8 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KFR09321.1 - 4.8e-64 213.2 2.8 8e-26 90.3 0.1 6.4 6 0 0 6 6 6 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 KFR09321.1 - 1.9e-32 111.5 0.0 1.5e-31 108.6 0.0 2.7 2 0 0 2 2 1 1 Midasin AAA lid domain AAA PF00004.29 KFR09321.1 - 3e-25 89.2 0.6 0.00094 19.6 0.1 7.0 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 KFR09321.1 - 5.6e-24 84.5 0.0 2.1e-07 30.8 0.0 7.2 7 0 0 7 7 7 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KFR09321.1 - 1.7e-22 79.8 3.0 0.00016 21.3 0.0 6.8 6 0 0 6 6 6 4 P-loop containing dynein motor region AAA_16 PF13191.6 KFR09321.1 - 6.3e-22 78.8 27.1 0.00065 20.1 0.1 10.4 10 2 1 11 11 9 6 AAA ATPase domain TsaE PF02367.17 KFR09321.1 - 1.3e-16 60.7 3.0 0.38 10.8 0.0 7.0 6 0 0 6 6 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynein_heavy PF03028.15 KFR09321.1 - 2e-16 60.2 0.0 0.0016 18.5 0.0 7.5 7 0 0 7 7 6 3 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 KFR09321.1 - 2.4e-16 60.2 6.5 0.0038 17.5 0.0 8.3 8 0 0 8 8 6 4 AAA domain AAA_18 PF13238.6 KFR09321.1 - 8.1e-16 58.7 10.1 0.14 12.8 0.0 9.8 10 0 0 10 10 7 4 AAA domain AAA_14 PF13173.6 KFR09321.1 - 4.7e-15 55.8 0.0 0.011 15.8 0.0 7.4 6 1 1 7 7 7 3 AAA domain Sigma54_activat PF00158.26 KFR09321.1 - 3.3e-14 52.9 0.7 0.74 9.5 0.0 7.1 7 0 0 7 7 7 3 Sigma-54 interaction domain ABC_tran PF00005.27 KFR09321.1 - 9.2e-14 52.1 9.9 0.02 15.4 0.0 8.2 8 0 0 8 8 6 2 ABC transporter Sigma54_activ_2 PF14532.6 KFR09321.1 - 2.4e-13 50.4 2.1 0.00051 20.2 0.0 7.4 7 0 0 7 7 7 1 Sigma-54 interaction domain AAA_6 PF12774.7 KFR09321.1 - 1.6e-11 43.8 1.5 0.083 11.8 0.0 6.5 6 0 0 6 6 6 3 Hydrolytic ATP binding site of dynein motor region RsgA_GTPase PF03193.16 KFR09321.1 - 4.7e-11 42.9 6.4 0.21 11.5 0.0 6.8 6 0 0 6 6 6 2 RsgA GTPase NACHT PF05729.12 KFR09321.1 - 1.2e-09 38.3 6.6 2 8.3 0.0 7.3 7 0 0 7 7 6 2 NACHT domain Mg_chelatase PF01078.21 KFR09321.1 - 1.4e-09 37.7 6.6 1.1 8.6 0.0 8.0 7 2 1 8 8 7 1 Magnesium chelatase, subunit ChlI Roc PF08477.13 KFR09321.1 - 8.3e-09 35.7 1.1 4.3 7.6 0.0 6.7 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 KFR09321.1 - 1.2e-08 34.4 1.8 0.085 12.0 0.0 5.7 6 0 0 6 6 6 2 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KFR09321.1 - 1.3e-08 35.2 0.5 5.5 7.4 0.0 6.9 6 0 0 6 6 6 0 RNA helicase AAA_33 PF13671.6 KFR09321.1 - 1.4e-08 35.0 1.9 0.36 11.0 0.0 6.6 6 0 0 6 6 6 2 AAA domain AAA_8 PF12780.7 KFR09321.1 - 1.4e-07 31.1 0.3 0.42 9.9 0.0 5.8 5 0 0 5 5 5 1 P-loop containing dynein motor region D4 PduV-EutP PF10662.9 KFR09321.1 - 3.5e-07 30.1 3.1 0.33 10.7 0.0 6.2 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 KFR09321.1 - 5.2e-07 29.8 1.8 8.3 6.3 0.0 6.1 5 0 0 5 5 5 0 Rad17 P-loop domain AAA_19 PF13245.6 KFR09321.1 - 5.9e-07 29.9 1.5 1.4 9.2 0.0 6.0 5 0 0 5 5 5 1 AAA domain AAA_28 PF13521.6 KFR09321.1 - 8e-07 29.4 6.9 3.1 8.0 0.0 7.2 7 0 0 7 7 6 1 AAA domain SRP54 PF00448.22 KFR09321.1 - 1.8e-06 27.8 1.0 2.9 7.5 0.0 5.2 5 0 0 5 5 5 1 SRP54-type protein, GTPase domain RuvB_N PF05496.12 KFR09321.1 - 1.8e-06 27.8 4.9 5.4 6.8 0.0 6.4 6 0 0 6 6 6 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 KFR09321.1 - 2.5e-06 27.1 0.9 13 5.6 0.0 6.3 6 0 0 6 6 6 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KFR09321.1 - 1.1e-05 25.5 0.6 12 6.1 0.0 6.4 6 0 0 6 6 6 0 50S ribosome-binding GTPase T2SSE PF00437.20 KFR09321.1 - 6.9e-05 22.0 1.7 26 3.7 0.1 5.9 6 0 0 6 6 6 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 KFR09321.1 - 9.9e-05 22.1 2.3 5.4 6.7 0.0 5.8 6 0 0 6 6 6 0 IstB-like ATP binding protein TniB PF05621.11 KFR09321.1 - 0.00021 20.8 0.3 1.1 8.6 0.0 5.1 6 0 0 6 6 5 1 Bacterial TniB protein SRPRB PF09439.10 KFR09321.1 - 0.00029 20.3 2.8 15 5.0 0.0 5.7 6 0 0 6 6 6 0 Signal recognition particle receptor beta subunit MCM PF00493.23 KFR09321.1 - 0.00031 19.9 0.0 0.52 9.4 0.0 4.4 4 0 0 4 4 4 1 MCM P-loop domain CPT PF07931.12 KFR09321.1 - 0.00043 20.2 2.5 13 5.5 0.0 6.0 7 0 0 7 7 6 0 Chloramphenicol phosphotransferase-like protein AAA_25 PF13481.6 KFR09321.1 - 0.00047 19.8 12.9 1.5 8.3 0.0 5.8 7 0 0 7 7 5 1 AAA domain DEAD PF00270.29 KFR09321.1 - 0.0013 18.6 0.1 5.5 6.7 0.0 4.3 4 0 0 4 4 4 0 DEAD/DEAH box helicase dNK PF01712.19 KFR09321.1 - 0.015 15.2 7.3 2.4 8.0 0.0 5.5 6 0 0 6 6 5 0 Deoxynucleoside kinase ATPase PF06745.13 KFR09321.1 - 0.02 14.2 0.9 3 7.1 0.0 3.6 3 0 0 3 3 3 0 KaiC ATP-synt_ab PF00006.25 KFR09321.1 - 0.033 13.8 0.0 9.7 5.8 0.0 3.5 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain CbiA PF01656.23 KFR09321.1 - 0.048 13.7 0.2 58 3.8 0.0 4.7 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 KFR09321.1 - 0.59 9.9 4.9 67 3.1 0.1 4.9 5 0 0 5 5 4 0 Conserved hypothetical ATP binding protein Ras PF00071.22 KFR09321.1 - 0.7 9.5 5.1 24 4.5 0.0 4.5 5 0 0 5 5 5 0 Ras family cobW PF02492.19 KFR09321.1 - 1.8 8.1 6.1 38 3.8 0.0 4.5 5 0 0 5 5 4 0 CobW/HypB/UreG, nucleotide-binding domain FNIP_M PF14637.6 KFR09321.1 - 2.4 8.1 7.3 0.44 10.5 0.2 3.1 3 0 0 3 3 2 0 Folliculin-interacting protein middle domain AAA_21 PF13304.6 KFR09321.1 - 3.6 7.3 7.3 23 4.6 0.0 4.5 4 0 0 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Complex1_LYR PF05347.15 KFR09322.1 - 3.8e-20 71.7 1.7 4.7e-20 71.4 1.7 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFR09322.1 - 3.4e-08 34.1 2.4 4.7e-08 33.7 2.4 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KFR09322.1 - 3.2e-05 24.4 0.5 3.8e-05 24.2 0.5 1.2 1 0 0 1 1 1 1 Complex1_LYR-like FERM_M PF00373.18 KFR09322.1 - 0.036 14.5 0.5 0.061 13.7 0.2 1.5 1 1 0 1 1 1 0 FERM central domain Ank_2 PF12796.7 KFR09323.1 - 4.3e-37 126.6 13.1 5.7e-14 52.5 0.3 3.7 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFR09323.1 - 8.6e-32 108.8 12.8 3.5e-09 36.8 0.1 5.5 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KFR09323.1 - 2.9e-30 103.4 20.3 7.8e-08 32.4 0.7 7.7 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 KFR09323.1 - 5.1e-30 103.5 12.8 3.7e-09 37.0 0.2 6.1 3 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFR09323.1 - 3.5e-28 94.5 7.1 1.4e-05 25.0 0.1 7.3 7 0 0 7 7 7 5 Ankyrin repeat Phasin PF05597.11 KFR09323.1 - 0.017 15.1 6.7 0.52 10.3 1.4 3.3 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) EccE PF11203.8 KFR09323.1 - 0.041 14.2 3.9 3.8 7.9 0.3 2.9 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE DUF5320 PF17253.2 KFR09323.1 - 0.4 11.8 2.1 1.4 10.1 2.1 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5320) CLZ PF16526.5 KFR09323.1 - 4.1 7.8 13.3 2.1 8.8 2.5 3.4 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Syntaxin_2 PF14523.6 KFR09323.1 - 7.5 7.0 11.4 2.5 8.5 2.6 2.8 2 0 0 2 2 2 0 Syntaxin-like protein Gtr1_RagA PF04670.12 KFR09324.1 - 3.4e-73 245.8 0.6 4.9e-73 245.3 0.6 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KFR09324.1 - 1e-06 28.3 0.0 1.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFR09324.1 - 1.5e-05 24.5 0.1 3.2e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KFR09324.1 - 2.5e-05 24.5 0.0 4.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFR09324.1 - 0.0016 18.0 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KFR09324.1 - 0.0082 16.2 0.0 0.025 14.7 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFR09324.1 - 0.14 12.5 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Neur_chan_LBD PF02931.23 KFR09326.1 - 6.9e-52 176.0 0.4 1.1e-51 175.3 0.4 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFR09326.1 - 3.5e-36 125.4 5.7 1.9e-31 110.0 4.3 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFR09327.1 - 1e-51 175.4 0.6 1.6e-51 174.8 0.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFR09327.1 - 3.1e-36 125.6 5.0 2.9e-31 109.3 2.3 2.4 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region M20_dimer PF07687.14 KFR09328.1 - 1.2e-09 38.1 0.0 2.1e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KFR09328.1 - 2.4e-06 27.4 0.1 3.4e-06 26.9 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 LytB_WW PF18342.1 KFR09328.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Endo-beta-N-acetylglucosaminidase LytB WW domain PNRC PF15365.6 KFR09329.1 - 3.4e-07 29.9 6.9 6.2e-07 29.0 6.9 1.5 1 0 0 1 1 1 1 Proline-rich nuclear receptor coactivator motif mRNA_cap_enzyme PF01331.19 KFR09330.1 - 1.9e-77 259.5 0.2 2.7e-77 259.0 0.2 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KFR09330.1 - 8.4e-20 71.4 0.0 1.7e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DSPc PF00782.20 KFR09330.1 - 1.6e-10 40.9 0.0 3.5e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DNA_ligase_A_M PF01068.21 KFR09330.1 - 1.2e-06 28.4 0.0 0.0093 15.6 0.0 2.4 1 1 1 2 2 2 2 ATP dependent DNA ligase domain Y_phosphatase PF00102.27 KFR09330.1 - 0.00033 20.3 0.0 0.00058 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFR09330.1 - 0.033 14.2 0.0 0.05 13.6 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KFR09330.1 - 0.042 13.4 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family 7tm_1 PF00001.21 KFR09331.1 - 2.1e-45 155.1 16.8 3.1e-45 154.5 16.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR09331.1 - 2e-12 47.1 16.9 2.9e-12 46.5 16.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFR09331.1 - 1.1e-09 38.4 13.7 1.5e-05 24.9 6.2 2.5 2 1 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFR09331.1 - 3.5e-07 30.1 9.5 3.5e-07 30.1 9.5 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx YlaC PF10777.9 KFR09331.1 - 0.038 13.8 3.5 0.1 12.4 0.3 2.6 3 0 0 3 3 3 0 Inner membrane protein YlaC Yae1_N PF09811.9 KFR09332.1 - 1.3e-09 37.6 32.1 6.3e+02 0.2 32.1 3.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal PET10 PF17316.2 KFR09333.1 - 0.035 13.6 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Petite colonies protein 10 DUF885 PF05960.11 KFR09333.1 - 0.057 13.1 0.1 0.063 12.9 0.1 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) ORC3_N PF07034.11 KFR09334.1 - 5e-127 423.6 6.1 1.1e-126 422.5 6.1 1.6 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 KFR09334.1 - 7.4e-29 100.6 0.0 4.6e-26 91.6 0.0 3.0 2 1 0 2 2 2 1 Origin recognition complex winged helix C-terminal Vac14_Fab1_bd PF12755.7 KFR09334.1 - 0.093 13.3 0.1 1.3 9.7 0.0 2.8 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Pex19 PF04614.12 KFR09334.1 - 0.88 9.3 4.4 2.5 7.8 1.8 2.4 2 0 0 2 2 2 0 Pex19 protein family tRNA-synt_1d PF00750.19 KFR09335.1 - 1.9e-90 303.3 3.5 2.4e-90 303.0 3.5 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KFR09335.1 - 1.3e-21 76.9 2.5 1.3e-21 76.9 0.3 2.2 2 0 0 2 2 2 1 DALR anticodon binding domain tRNA-synt_1g PF09334.11 KFR09335.1 - 0.0097 14.7 0.4 0.3 9.8 0.1 2.4 1 1 1 2 2 2 2 tRNA synthetases class I (M) Nuc_sug_transp PF04142.15 KFR09336.1 - 1.7e-122 408.5 24.8 1.9e-122 408.3 24.8 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KFR09336.1 - 0.018 15.2 33.6 0.57 10.4 7.8 2.9 2 1 0 2 2 2 0 EamA-like transporter family DUF202 PF02656.15 KFR09336.1 - 0.21 12.0 0.2 0.21 12.0 0.2 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF202) FAP206 PF12018.8 KFR09337.1 - 1.7e-97 326.2 4.6 3.9e-97 325.1 4.6 1.6 1 0 0 1 1 1 1 Domain of unknown function PMD PF10536.9 KFR09337.1 - 0.04 13.0 0.1 0.084 12.0 0.1 1.4 1 0 0 1 1 1 0 Plant mobile domain DUF2258 PF10015.9 KFR09338.1 - 4.9 7.4 6.9 1.2 9.3 1.7 2.6 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2258) DUF4500 PF14937.6 KFR09339.1 - 7.4e-28 96.4 0.0 7.9e-28 96.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4500) Spore_YhaL PF14147.6 KFR09339.1 - 0.055 13.2 0.0 0.068 12.9 0.0 1.1 1 0 0 1 1 1 0 Sporulation protein YhaL DDDD PF10161.9 KFR09339.1 - 0.12 12.2 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative mitochondrial precursor protein Connexin PF00029.19 KFR09340.1 - 1.9e-76 256.9 13.0 1.8e-43 149.0 0.5 2.0 1 1 1 2 2 2 2 Connexin zf-C2H2 PF00096.26 KFR09341.1 - 2.2e-15 56.2 96.4 0.0066 16.9 0.2 16.2 16 0 0 16 16 16 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFR09341.1 - 5.1e-12 45.6 96.5 0.22 12.5 2.3 16.1 16 0 0 16 16 16 9 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFR09341.1 - 0.00012 22.0 39.4 0.26 11.3 0.6 8.3 9 0 0 9 9 8 4 C2H2-type zinc finger zinc_ribbon_11 PF11682.8 KFR09341.1 - 0.0024 17.9 0.4 0.014 15.4 0.4 2.4 1 0 0 1 1 1 1 Probable zinc-ribbon Zn-C2H2_12 PF18112.1 KFR09341.1 - 0.0056 17.1 5.2 0.65 10.5 0.2 3.6 2 0 0 2 2 2 2 Autophagy receptor zinc finger-C2H2 domain zf-H2C2_5 PF13909.6 KFR09341.1 - 0.03 14.1 6.9 1.6 8.6 0.1 4.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf_Hakai PF18408.1 KFR09341.1 - 0.047 13.4 24.7 0.56 10.0 0.1 6.3 6 0 0 6 6 6 0 C2H2 Hakai zinc finger domain zf_C2H2_ZHX PF18387.1 KFR09341.1 - 0.05 13.2 1.3 0.36 10.5 0.1 3.3 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain FOXP-CC PF16159.5 KFR09341.1 - 0.092 13.4 44.4 3.3 8.4 0.0 12.3 9 2 3 13 13 13 0 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KFR09341.1 - 0.21 11.9 49.5 3.3 8.1 2.4 10.4 9 2 2 11 11 11 0 C2H2-type zinc ribbon Zn_ribbon_SprT PF17283.2 KFR09341.1 - 0.29 11.1 5.4 0.76 9.7 1.7 3.0 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Zf_RING PF16744.5 KFR09341.1 - 0.49 10.5 3.8 1.4 9.1 0.1 3.8 3 0 0 3 3 3 0 KIAA1045 RING finger zf-C2HE PF16278.5 KFR09341.1 - 4.7 7.7 13.2 4.6 7.8 3.9 4.4 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Hormone_6 PF00236.18 KFR09342.1 - 6.7e-53 176.7 8.9 8e-53 176.4 8.9 1.1 1 0 0 1 1 1 1 Glycoprotein hormone PDGF PF00341.17 KFR09342.1 - 0.07 13.4 8.9 0.13 12.6 8.9 1.5 1 1 0 1 1 1 0 PDGF/VEGF domain 7tm_1 PF00001.21 KFR09343.1 - 9.6e-74 248.0 11.8 1.2e-73 247.7 11.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFR09343.1 - 1.2e-08 34.9 17.2 2.1e-08 34.2 17.2 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFR09343.1 - 4.9e-07 29.4 13.0 1e-06 28.3 13.0 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFR09343.1 - 6.4e-05 22.8 12.9 0.00093 19.0 12.9 2.1 1 1 0 1 1 1 1 Olfactory receptor RRM_1 PF00076.22 KFR09344.1 - 2e-45 152.5 1.3 8.6e-16 57.5 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) hnRNP_Q_AcD PF18360.1 KFR09344.1 - 3.2e-33 113.5 0.3 1.9e-32 111.0 0.1 2.2 2 0 0 2 2 2 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain RRM_5 PF13893.6 KFR09344.1 - 6.3e-07 29.0 0.0 0.00027 20.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFR09344.1 - 3e-06 27.2 0.3 0.92 9.7 0.0 4.3 3 2 0 3 3 3 2 RNA recognition motif Limkain-b1 PF11608.8 KFR09344.1 - 7.7e-05 22.7 0.1 0.31 11.1 0.1 3.6 3 1 0 3 3 3 2 Limkain b1 RRM_occluded PF16842.5 KFR09344.1 - 0.0039 17.0 0.1 0.081 12.8 0.0 2.9 3 0 0 3 3 3 1 Occluded RNA-recognition motif Calcipressin PF04847.12 KFR09344.1 - 0.019 14.7 0.1 0.14 11.9 0.3 2.3 3 0 0 3 3 3 0 Calcipressin PHM7_cyt PF14703.6 KFR09344.1 - 0.02 15.1 2.4 7.5 6.8 0.1 4.3 3 2 0 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter PXA PF02194.15 KFR09345.1 - 1.3e-37 129.5 0.4 5.2e-37 127.6 0.3 2.1 2 0 0 2 2 2 1 PXA domain PX PF00787.24 KFR09345.1 - 2.2e-20 72.7 1.1 2.2e-20 72.7 1.1 2.8 3 0 0 3 3 3 1 PX domain Nexin_C PF08628.12 KFR09345.1 - 8e-15 55.4 0.0 2.8e-14 53.7 0.0 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal RGS PF00615.19 KFR09345.1 - 4.7e-12 46.2 1.6 1.6e-11 44.5 1.6 2.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain dDENN PF03455.19 KFR09345.1 - 0.4 10.7 3.2 3.8 7.6 0.4 3.7 4 0 0 4 4 4 0 dDENN domain 5_nucleotid_C PF02872.18 KFR09346.1 - 3.8e-40 137.7 0.0 7.5e-40 136.7 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KFR09346.1 - 1.6e-07 32.0 0.0 3.1e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.25 KFR09347.1 - 2.2e-73 246.9 0.0 2.7e-73 246.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR09347.1 - 3.5e-42 144.5 0.0 5e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR09347.1 - 2.2e-11 43.6 0.1 7e-10 38.7 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 KFR09347.1 - 2.6e-05 23.7 0.1 4.7e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFR09347.1 - 0.00011 21.3 0.3 0.00015 20.9 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KFR09347.1 - 0.00045 19.9 0.3 0.00078 19.1 0.3 1.4 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 KFR09347.1 - 0.0013 18.8 0.3 0.0029 17.5 0.3 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KFR09347.1 - 0.04 13.5 0.1 0.059 13.0 0.1 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 WaaY PF06176.11 KFR09347.1 - 0.075 12.6 0.8 0.34 10.5 0.8 1.9 1 1 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) T-box PF00907.22 KFR09348.1 - 6.2e-78 261.3 0.0 7e-78 261.1 0.0 1.0 1 0 0 1 1 1 1 T-box Glyco_hydro_36C PF16874.5 KFR09348.1 - 0.16 12.5 0.0 0.33 11.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 36 C-terminal domain MRAP PF15183.6 KFR09349.1 - 5.4e-34 116.0 0.1 8.5e-34 115.4 0.1 1.2 1 0 0 1 1 1 1 Melanocortin-2 receptor accessory protein family SelK_SelG PF10961.8 KFR09349.1 - 0.18 12.4 0.7 0.51 11.0 0.2 1.9 1 1 1 2 2 2 0 Selenoprotein SelK_SelG Cyt-b5 PF00173.28 KFR09350.1 - 4.1e-24 84.5 0.0 1e-23 83.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.24 KFR09350.1 - 1.4e-18 67.1 0.0 5.8e-18 65.1 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KFR09350.1 - 4.3e-17 62.7 0.0 1.4e-16 61.1 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain CS PF04969.16 KFR09350.1 - 1e-07 32.9 1.4 3e-07 31.4 1.4 1.9 1 0 0 1 1 1 1 CS domain NAD_binding_6 PF08030.12 KFR09350.1 - 0.00022 21.4 0.0 0.0056 16.8 0.0 2.3 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Ripply PF14998.6 KFR09351.1 - 3.8e-24 85.1 0.4 4.3e-24 85.0 0.4 1.0 1 0 0 1 1 1 1 Transcription Regulator ANTH PF07651.16 KFR09352.1 - 6.5e-85 284.5 0.5 7.8e-85 284.2 0.5 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KFR09352.1 - 7.1e-15 55.2 0.0 1.2e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 ENTH domain VHS PF00790.19 KFR09352.1 - 0.054 13.3 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 VHS domain TALPID3 PF15324.6 KFR09352.1 - 4.9 4.7 9.3 8.2 3.9 9.3 1.3 1 0 0 1 1 1 0 Hedgehog signalling target Trypsin PF00089.26 KFR09353.1 - 3.3e-11 43.4 0.0 6.7e-09 35.9 0.0 2.5 3 0 0 3 3 3 2 Trypsin Trypsin_2 PF13365.6 KFR09353.1 - 2.3e-06 28.6 0.0 4.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain LAP1C PF05609.12 KFR09353.1 - 0.0099 15.0 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) DUF316 PF03761.15 KFR09353.1 - 0.085 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 Malic_M PF03949.15 KFR09354.1 - 1.4e-100 335.8 0.3 1.8e-100 335.5 0.3 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KFR09354.1 - 6.8e-81 270.4 0.0 1.1e-80 269.8 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain RWD PF05773.22 KFR09355.1 - 2.2e-15 57.0 0.1 3.9e-15 56.1 0.1 1.4 1 0 0 1 1 1 1 RWD domain DUF1115 PF06544.12 KFR09355.1 - 8.3e-15 55.2 0.1 3.7e-14 53.1 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) Acylphosphatase PF00708.18 KFR09355.1 - 0.028 14.8 0.0 0.068 13.6 0.0 1.7 1 0 0 1 1 1 0 Acylphosphatase PGM_PMM_I PF02878.16 KFR09356.1 - 4e-20 71.9 0.2 1e-08 35.0 0.0 3.6 2 2 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KFR09356.1 - 3.1e-11 43.3 0.3 3.1e-11 43.3 0.3 2.6 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 KFR09356.1 - 0.00047 20.3 0.5 0.0015 18.7 0.5 1.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III CinA_KH PF18146.1 KFR09356.1 - 0.003 17.7 0.9 0.48 10.6 0.0 2.8 2 0 0 2 2 2 1 Damage-inducible protein CinA KH domain DUF4385 PF14328.6 KFR09356.1 - 0.026 14.6 0.1 3.7 7.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4385) Terminase_2 PF03592.16 KFR09356.1 - 0.19 12.2 3.4 0.089 13.3 1.0 1.7 2 0 0 2 2 2 0 Terminase small subunit Histone_HNS PF00816.21 KFR09356.1 - 0.72 10.7 2.9 9.4 7.1 0.4 2.7 3 0 0 3 3 3 0 H-NS histone family Dopey_N PF04118.14 KFR09357.1 - 6e-106 354.0 0.5 4.1e-105 351.3 0.1 2.7 3 0 0 3 3 3 1 Dopey, N-terminal HECT_2 PF09814.9 KFR09359.1 - 1.3e-70 238.2 0.4 1.6e-70 237.9 0.4 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Ribosomal_S27e PF01667.17 KFR09359.1 - 0.12 12.1 1.4 6 6.6 0.1 2.5 2 0 0 2 2 2 0 Ribosomal protein S27 RCC1 PF00415.18 KFR09364.1 - 4.5e-36 123.2 12.8 1.5e-11 44.7 0.1 4.9 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KFR09364.1 - 1.1e-31 109.4 7.0 8.6e-16 58.2 1.2 3.1 2 1 1 3 3 3 2 BTB/POZ domain RCC1_2 PF13540.6 KFR09364.1 - 1.1e-10 41.0 13.7 6.1e-05 22.7 0.0 6.3 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat Ank_5 PF13857.6 KFR09364.1 - 4.9e-10 39.5 0.0 8.3e-06 26.0 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFR09364.1 - 1e-08 35.5 0.0 3.8e-05 24.2 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFR09364.1 - 2.9e-08 34.2 0.0 8.2e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFR09364.1 - 0.00019 21.6 0.0 1.7 9.4 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KFR09364.1 - 0.001 19.4 0.0 0.29 11.7 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Bcr-Abl_Oligo PF09036.10 KFR09364.1 - 0.041 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain DUF1265 PF06887.14 KFR09364.1 - 0.13 12.2 0.5 0.34 10.9 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1265) NTP_transf_7 PF07984.12 KFR09365.1 - 1e-132 442.3 0.7 1.2e-132 442.1 0.7 1.0 1 0 0 1 1 1 1 Nucleotidyltransferase DUF1803 PF08820.10 KFR09365.1 - 0.051 13.6 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1803) Transket_pyr PF02779.24 KFR09368.1 - 2.5e-39 134.8 0.0 3.4e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFR09368.1 - 5.9e-36 123.1 0.0 1.1e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Pkinase PF00069.25 KFR09371.1 - 2.2e-64 217.4 0.7 3.8e-64 216.6 0.7 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFR09371.1 - 2.2e-33 115.7 0.1 3.8e-33 114.9 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFR09371.1 - 1.6e-08 34.2 0.0 1.1e-05 24.9 0.0 2.8 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KFR09371.1 - 1.6e-05 25.0 0.4 0.31 10.9 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KFR09371.1 - 0.00022 20.6 0.1 0.00047 19.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KFR09371.1 - 0.0006 19.5 0.1 0.33 10.5 0.0 2.6 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KFR09371.1 - 0.0013 18.4 2.7 0.011 15.3 0.1 2.3 1 1 0 2 2 2 1 RIO1 family Mad3_BUB1_I_2 PF17014.5 KFR09371.1 - 0.0088 16.2 0.1 0.03 14.4 0.1 1.9 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Tubulin PF00091.25 KFR09371.1 - 0.011 15.9 0.2 0.037 14.2 0.0 1.8 2 0 0 2 2 2 0 Tubulin/FtsZ family, GTPase domain Mad3_BUB1_I PF08311.12 KFR09371.1 - 0.013 15.5 0.0 0.044 13.8 0.0 2.0 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 Kinase-PolyVal PF18762.1 KFR09371.1 - 0.038 14.0 0.9 0.1 12.5 0.9 1.7 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins ELO PF01151.18 KFR09373.1 - 9.1e-65 218.6 24.5 1.1e-64 218.4 24.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Lebercilin PF15619.6 KFR09374.1 - 4e-69 232.2 51.6 4e-69 232.2 51.6 2.3 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease Tantalus PF15386.6 KFR09374.1 - 0.087 12.9 1.6 0.39 10.9 1.6 2.2 1 0 0 1 1 1 0 Drosophila Tantalus-like FUSC PF04632.12 KFR09374.1 - 5.1 5.5 11.7 8.4 4.8 11.7 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family HMG14_17 PF01101.18 KFR09376.1 - 1.6e-21 77.1 22.4 1.7e-21 77.0 22.4 1.0 1 0 0 1 1 1 1 HMG14 and HMG17 TT_ORF2 PF02957.15 KFR09376.1 - 0.13 13.2 9.9 0.15 13.0 9.9 1.0 1 0 0 1 1 1 0 TT viral ORF2 DUF2477 PF10631.9 KFR09376.1 - 0.33 11.6 3.3 0.35 11.5 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) Bromodomain PF00439.25 KFR09377.1 - 5.7e-38 128.9 1.2 3.3e-18 65.5 0.0 3.2 3 0 0 3 3 3 2 Bromodomain WD40 PF00400.32 KFR09377.1 - 3.6e-33 113.0 15.1 3.2e-05 24.6 0.1 8.7 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFR09377.1 - 0.00068 19.9 0.3 0.5 10.7 0.1 4.1 3 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain YccV-like PF08755.11 KFR09378.1 - 3.7e-20 72.3 0.0 7.2e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like DUF4542 PF15075.6 KFR09378.1 - 0.0079 16.6 0.1 0.013 15.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4542) DUF5623 PF18536.1 KFR09378.1 - 0.071 13.4 0.5 0.18 12.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5623) Mei4 PF13971.6 KFR09379.1 - 3e-79 267.0 11.9 3.6e-79 266.8 11.9 1.0 1 0 0 1 1 1 1 Meiosis-specific protein Mei4 7tm_1 PF00001.21 KFR09381.1 - 4.3e-83 278.7 11.8 5.1e-83 278.4 11.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFR09381.1 - 1e-10 41.4 10.5 9.3e-10 38.3 10.5 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFR09381.1 - 4e-07 30.0 9.5 2e-05 24.5 5.5 2.2 2 0 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFR09381.1 - 1.1e-06 28.5 8.2 1.1e-06 28.5 8.2 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF1761 PF08570.10 KFR09381.1 - 1 9.6 10.2 1.1 9.5 0.0 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1761) SEA PF01390.20 KFR09383.1 - 4.1e-32 110.4 2.3 4.2e-16 58.9 0.2 2.6 2 0 0 2 2 2 2 SEA domain DUF4214 PF13946.6 KFR09383.1 - 0.028 14.5 0.0 0.063 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4214) Plasmod_Pvs28 PF06247.11 KFR09383.1 - 0.19 12.1 1.8 0.46 10.8 1.8 1.6 1 0 0 1 1 1 0 Pvs28 EGF domain Peptidase_C48 PF02902.19 KFR09384.1 - 1.2e-33 116.8 3.1 6.2e-20 72.0 0.8 2.5 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain CortBP2 PF09727.9 KFR09385.1 - 1.1e-50 172.2 20.8 1.1e-50 172.2 20.8 7.2 2 1 4 7 7 7 2 Cortactin-binding protein-2 Arm-DNA-bind_2 PF12167.8 KFR09385.1 - 0.033 14.1 0.3 0.14 12.1 0.3 2.1 1 0 0 1 1 1 0 Arm DNA-binding domain T2SSF PF00482.23 KFR09385.1 - 5.5 7.0 5.6 12 5.9 0.1 3.8 4 0 0 4 4 4 0 Type II secretion system (T2SS), protein F BAAT_C PF08840.11 KFR09385.1 - 8.9 6.2 11.7 0.14 12.0 2.3 2.8 2 1 0 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal CDC50 PF03381.15 KFR09386.1 - 2.2e-93 312.8 0.2 2.6e-93 312.6 0.2 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family VWA PF00092.28 KFR09387.1 - 2.1e-08 34.6 0.3 5e-08 33.4 0.1 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain Toxin_R_bind_N PF07953.12 KFR09387.1 - 0.016 14.9 0.1 0.027 14.2 0.1 1.3 1 0 0 1 1 1 0 Clostridium neurotoxin, N-terminal receptor binding Pfk_N PF18468.1 KFR09387.1 - 0.052 14.0 0.1 1.6 9.2 0.0 2.3 2 0 0 2 2 2 0 Phosphofructokinase N-terminal domain yeast Laminin_G_3 PF13385.6 KFR09387.1 - 0.08 13.1 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily MFS_1 PF07690.16 KFR09388.1 - 5.1e-57 193.4 34.8 7.9e-57 192.8 26.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cas1_AcylT PF07779.12 KFR09388.1 - 0.0053 15.7 2.1 0.0098 14.8 2.1 1.3 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p GTP_EFTU PF00009.27 KFR09389.1 - 1.8e-54 184.2 0.0 2.6e-54 183.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFR09389.1 - 2.3e-40 137.4 0.0 5e-40 136.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KFR09389.1 - 4.1e-15 55.9 1.9 6.3e-15 55.3 0.6 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFR09389.1 - 0.00031 20.8 0.2 0.0083 16.2 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KFR09389.1 - 0.017 15.0 1.2 0.031 14.2 0.2 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Dynamin_N PF00350.23 KFR09389.1 - 0.079 13.0 0.1 17 5.4 0.1 2.4 2 0 0 2 2 2 0 Dynamin family G-alpha PF00503.20 KFR09389.1 - 0.24 10.5 0.2 0.7 9.0 0.1 1.8 2 0 0 2 2 2 0 G-protein alpha subunit GIDA PF01134.22 KFR09390.1 - 2.7e-105 352.7 0.0 3.6e-105 352.3 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KFR09390.1 - 1.9e-65 221.0 0.0 2.8e-65 220.5 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain Hexapep_2 PF14602.6 KFR09390.1 - 0.019 14.7 0.6 0.036 13.8 0.6 1.5 1 0 0 1 1 1 0 Hexapeptide repeat of succinyl-transferase Mab-21 PF03281.14 KFR09391.1 - 5.4e-77 259.0 6.1 6e-77 258.8 6.1 1.0 1 0 0 1 1 1 1 Mab-21 protein DEAD PF00270.29 KFR09392.1 - 2.3e-38 131.7 0.0 5.4e-38 130.5 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFR09392.1 - 5.9e-29 100.6 0.0 9.1e-28 96.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain KH_1 PF00013.29 KFR09392.1 - 3.3e-10 39.6 0.1 7.6e-10 38.5 0.1 1.6 1 0 0 1 1 1 1 KH domain MOEP19 PF16005.5 KFR09392.1 - 2.8e-07 30.4 0.0 3.9e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 KH-like RNA-binding domain ResIII PF04851.15 KFR09392.1 - 0.0052 16.8 0.0 0.015 15.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit KH_2 PF07650.17 KFR09392.1 - 0.0068 16.2 0.2 0.034 14.0 0.2 2.2 1 0 0 1 1 1 1 KH domain KH_5 PF13184.6 KFR09392.1 - 0.13 12.4 0.7 0.38 10.9 0.1 2.1 2 0 0 2 2 2 0 NusA-like KH domain KCNQ_channel PF03520.14 KFR09393.1 - 4.6e-94 313.6 1.5 4.6e-94 313.6 1.5 1.6 2 0 0 2 2 2 1 KCNQ voltage-gated potassium channel Ion_trans PF00520.31 KFR09393.1 - 2.9e-26 92.2 10.7 4.1e-26 91.7 10.7 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFR09393.1 - 3e-14 52.8 5.7 8.1e-14 51.4 5.7 1.8 1 0 0 1 1 1 1 Ion channel IQ PF00612.27 KFR09393.1 - 1.7 8.7 5.1 1.1 9.2 0.1 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif LLC1 PF14945.6 KFR09393.1 - 1.8 9.2 4.1 0.84 10.2 0.6 2.3 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein C2 PF00168.30 KFR09395.1 - 1.3e-39 134.7 0.0 5e-19 68.5 0.0 2.8 2 0 0 2 2 2 2 C2 domain PDZ PF00595.24 KFR09395.1 - 6e-10 39.3 0.0 1.3e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFR09395.1 - 1.6e-09 37.5 0.0 3.2e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain FYVE_2 PF02318.16 KFR09395.1 - 1.1e-07 32.0 7.0 3.5e-07 30.4 7.0 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger zf-piccolo PF05715.13 KFR09395.1 - 9.2 6.5 11.3 25 5.1 11.3 1.8 1 0 0 1 1 1 0 Piccolo Zn-finger Asparaginase_2 PF01112.18 KFR09396.1 - 4e-116 387.3 3.8 4.7e-116 387.1 3.8 1.0 1 0 0 1 1 1 1 Asparaginase Glyco_transf_43 PF03360.16 KFR09397.1 - 9.9e-37 126.8 0.1 1.1e-36 126.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 ArfGap PF01412.18 KFR09398.1 - 6e-33 113.4 0.2 6e-33 113.4 0.2 1.9 1 1 1 2 2 2 1 Putative GTPase activating protein for Arf DUF2151 PF10221.9 KFR09398.1 - 0.018 13.6 3.2 0.019 13.6 2.5 1.3 1 1 0 1 1 1 0 Cell cycle and development regulator Afi1 PF07792.12 KFR09398.1 - 0.16 12.4 5.6 0.35 11.3 5.6 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking EMC3_TMCO1 PF01956.16 KFR09398.1 - 0.17 11.6 1.3 0.32 10.7 0.0 2.1 2 1 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Presenilin PF01080.17 KFR09398.1 - 2 7.1 5.7 3.3 6.4 5.7 1.3 1 0 0 1 1 1 0 Presenilin Sec62 PF03839.16 KFR09398.1 - 6.6 6.2 9.6 12 5.3 9.6 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 PcfK PF14058.6 KFR09398.1 - 7.6 6.8 17.0 2.7 8.3 13.5 2.0 2 0 0 2 2 2 0 PcfK-like protein PWWP PF00855.17 KFR09398.1 - 9.5 6.7 8.7 20 5.7 7.4 2.2 1 1 1 2 2 2 0 PWWP domain DUF1674 PF07896.12 KFR09399.1 - 5.4e-19 68.4 5.3 5.4e-19 68.4 5.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) DUF676 PF05057.14 KFR09400.1 - 5.8e-61 205.8 0.0 1.1e-60 204.8 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3657 PF12394.8 KFR09400.1 - 2.3e-19 69.7 3.8 3.8e-19 69.0 1.9 2.6 2 0 0 2 2 2 1 Protein FAM135 Palm_thioest PF02089.15 KFR09400.1 - 2.2e-08 34.3 0.0 5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 KFR09400.1 - 2.8e-05 24.0 0.0 6.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 KFR09400.1 - 0.001 18.3 0.1 0.002 17.4 0.1 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase LMBR1 PF04791.16 KFR09402.1 - 2e-23 83.1 21.2 5e-22 78.5 21.2 2.3 1 1 0 1 1 1 1 LMBR1-like membrane protein Spore_YhaL PF14147.6 KFR09402.1 - 0.8 9.4 3.5 32 4.3 0.1 3.5 2 0 0 2 2 2 0 Sporulation protein YhaL 7tm_2 PF00002.24 KFR09403.1 - 4.6e-59 199.7 15.3 7.2e-59 199.0 15.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) TSP_1 PF00090.19 KFR09403.1 - 5.3e-40 135.4 79.2 1.2e-12 47.9 10.7 5.1 5 0 0 5 5 5 4 Thrombospondin type 1 domain GAIN PF16489.5 KFR09403.1 - 3.3e-35 121.4 0.2 5.3e-35 120.7 0.2 1.3 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain GPS PF01825.21 KFR09403.1 - 4.6e-14 52.7 3.1 4.6e-14 52.7 3.1 2.6 3 0 0 3 3 3 1 GPCR proteolysis site, GPS, motif HRM PF02793.22 KFR09403.1 - 3.4e-07 30.5 0.4 3.4e-07 30.5 0.4 4.1 3 1 0 3 3 3 1 Hormone receptor domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Chordates/Nipponia_nippon-ASM70822v1/GCA_000708225.1_ASM70822v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Chordates/Nipponia_nippon-ASM70822v1/GCA_000708225.1_ASM70822v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Chordates/Nipponia_nippon-ASM70822v1/GCA_000708225.1_ASM70822v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Chordates/Nipponia_nippon-ASM70822v1/GCA_000708225.1_ASM70822v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 18:09:56 2019 # [ok]